# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- WYL PF13280.6 EMT49933.1 - 2.1e-23 83.3 0.0 3e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 EMT49933.1 - 2.4e-13 49.8 0.0 4.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_DeoR PF08220.12 EMT49933.1 - 6.6e-10 38.6 0.0 1.5e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 EMT49933.1 - 0.00035 20.9 0.0 0.00064 20.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator HTH_Mga PF08280.11 EMT49933.1 - 0.024 14.6 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HrcA_DNA-bdg PF03444.15 EMT49933.1 - 0.028 14.1 0.1 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding SpoIIID PF12116.8 EMT49933.1 - 0.035 14.2 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D GntR PF00392.21 EMT49933.1 - 0.043 13.5 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_36 PF13730.6 EMT49933.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_ECF PF07638.11 EMT49933.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor HTH_10 PF04967.12 EMT49933.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain DinB PF05163.12 EMT49934.1 - 1.6e-10 41.2 1.1 1.9e-10 40.9 1.1 1.2 1 0 0 1 1 1 1 DinB family DinB_2 PF12867.7 EMT49934.1 - 9.5e-10 39.1 0.8 1.2e-09 38.8 0.8 1.1 1 0 0 1 1 1 1 DinB superfamily CENP-F_leu_zip PF10473.9 EMT49934.1 - 0.0043 17.1 2.3 0.33 11.0 0.6 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3417 PF11897.8 EMT49934.1 - 0.019 15.4 0.3 2 8.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) Mo25 PF08569.11 EMT49934.1 - 0.03 13.7 0.4 0.076 12.4 0.1 1.6 1 1 1 2 2 2 0 Mo25-like DUF1706 PF08020.11 EMT49934.1 - 0.057 13.3 0.3 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) Sec2p PF06428.11 EMT49934.1 - 0.2 11.7 1.0 0.48 10.4 0.2 2.0 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p HTH_25 PF13413.6 EMT49934.1 - 0.68 9.8 2.6 0.89 9.5 0.2 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain FIVAR PF07554.13 EMT49935.1 - 6.3e-40 135.8 34.6 9.2e-11 42.4 2.9 4.6 4 0 0 4 4 4 4 FIVAR domain SLH PF00395.20 EMT49935.1 - 2.4e-37 126.7 8.2 5.5e-13 48.7 0.3 5.1 4 0 0 4 4 4 4 S-layer homology domain CAMP_factor PF07373.11 EMT49935.1 - 7.2e-12 45.4 10.4 0.013 15.1 0.1 4.4 4 0 0 4 4 4 4 CAMP factor (Cfa) Big_6 PF17936.1 EMT49935.1 - 6.8e-08 32.7 3.7 6.8e-08 32.7 3.7 3.1 3 0 0 3 3 3 1 Bacterial Ig domain DUF148 PF02520.17 EMT49935.1 - 1.7e-06 28.1 14.0 0.029 14.5 0.7 4.6 3 1 1 4 4 4 3 Domain of unknown function DUF148 DUF3080 PF11279.8 EMT49935.1 - 2.9e-05 23.5 12.1 0.032 13.5 3.1 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3080) Big_3_3 PF13750.6 EMT49935.1 - 0.00033 20.3 1.5 0.3 10.7 0.1 2.5 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 3) Bep_C_terminal PF17841.1 EMT49935.1 - 0.0012 19.0 7.5 3.6 7.9 0.3 4.3 4 0 0 4 4 4 1 BID domain of Bartonella effector protein (Bep) Phage_TAC_12 PF12363.8 EMT49935.1 - 0.014 15.8 10.6 0.48 10.8 0.6 4.6 3 1 1 4 4 4 0 Phage tail assembly chaperone protein, TAC DUF1542 PF07564.11 EMT49935.1 - 0.015 15.4 6.0 0.015 15.4 6.0 6.0 5 2 1 6 6 6 0 Domain of Unknown Function (DUF1542) ZapD PF07072.11 EMT49935.1 - 0.015 15.0 16.9 1.1 9.0 0.8 4.4 4 0 0 4 4 4 0 Cell division protein Retrotrans_gag PF03732.17 EMT49935.1 - 0.019 15.2 6.7 10 6.5 0.5 4.2 3 1 1 4 4 4 0 Retrotransposon gag protein Spectrin PF00435.21 EMT49935.1 - 0.021 15.3 18.4 2.4 8.7 0.7 4.4 2 1 2 4 4 4 0 Spectrin repeat NPCBM_assoc PF10633.9 EMT49935.1 - 0.043 14.1 5.5 0.28 11.4 0.6 3.3 2 1 1 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SapB_1 PF05184.15 EMT49935.1 - 0.049 13.7 4.2 42 4.3 0.1 4.4 4 0 0 4 4 4 0 Saposin-like type B, region 1 RecG_N PF17190.4 EMT49935.1 - 0.093 13.5 6.5 33 5.3 0.3 4.5 3 1 2 6 6 5 0 RecG N-terminal helical domain Tex_N PF09371.10 EMT49935.1 - 0.14 11.8 17.1 1.2 8.8 0.2 4.1 1 1 3 4 4 4 0 Tex-like protein N-terminal domain EF1_GNE PF00736.19 EMT49935.1 - 0.22 11.7 15.1 1.2 9.4 0.3 4.3 3 1 1 4 4 4 0 EF-1 guanine nucleotide exchange domain V-SNARE PF05008.15 EMT49935.1 - 0.24 11.8 18.8 2 8.8 1.1 4.8 5 0 0 5 5 5 0 Vesicle transport v-SNARE protein N-terminus NYD-SP28_assoc PF14775.6 EMT49935.1 - 0.32 11.1 13.3 27 4.9 0.2 5.0 5 1 0 5 5 5 0 Sperm tail C-terminal domain CENP-H PF05837.12 EMT49935.1 - 1.2 9.6 29.8 3.4 8.1 1.4 4.2 3 1 1 4 4 4 0 Centromere protein H (CENP-H) PemK_toxin PF02452.17 EMT49935.1 - 2.1 8.8 5.4 5.5 7.4 0.1 3.6 4 0 0 4 4 3 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system DUF3160 PF11369.8 EMT49935.1 - 3.1 6.1 14.8 1.9 6.9 2.1 3.4 1 1 2 4 4 4 0 Protein of unknown function (DUF3160) ATP-synt_DE PF00401.20 EMT49935.1 - 7.6 6.9 32.1 5.1 7.4 1.7 5.1 4 0 0 4 4 4 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DEDD_Tnp_IS110 PF01548.17 EMT49936.1 - 1.7e-22 80.0 0.0 4.3e-22 78.6 0.0 1.7 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.16 EMT49936.1 - 2.5e-21 75.8 0.0 4.1e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family HTH_26 PF13443.6 EMT49937.1 - 3.1e-20 72.4 0.9 3.4e-20 72.2 0.9 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 EMT49937.1 - 8.5e-13 48.2 0.1 1e-12 47.9 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EMT49937.1 - 6.9e-09 35.6 0.2 8.9e-09 35.2 0.2 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EMT49937.1 - 3.6e-07 30.4 0.1 4.2e-07 30.2 0.1 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 EMT49937.1 - 4.7e-07 29.7 0.2 5.2e-07 29.5 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 EMT49937.1 - 1.1e-05 24.9 0.6 2.5e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 EMT49937.1 - 0.0021 17.8 0.3 0.0033 17.2 0.3 1.5 1 1 0 1 1 1 1 IclR helix-turn-helix domain HTH_35 PF13693.6 EMT49937.1 - 0.018 15.1 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_25 PF13413.6 EMT49937.1 - 0.022 14.6 0.3 0.033 14.0 0.3 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 EMT49937.1 - 0.028 14.3 0.4 0.067 13.0 0.1 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain YdaS_antitoxin PF15943.5 EMT49937.1 - 0.036 13.9 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Crp_2 PF13545.6 EMT49937.1 - 0.037 14.0 0.2 0.053 13.5 0.1 1.5 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 EMT49937.1 - 0.038 13.9 0.2 0.055 13.4 0.2 1.3 1 1 0 1 1 1 0 MarR family RHH_1 PF01402.21 EMT49937.1 - 0.057 13.4 0.9 0.8 9.7 0.0 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HNF-1_N PF04814.13 EMT49937.1 - 0.058 14.0 0.0 0.065 13.9 0.0 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Rep_trans PF02486.19 EMT49938.1 - 7.5e-06 25.8 0.1 1e-05 25.3 0.1 1.3 1 1 0 1 1 1 1 Replication initiation factor DUF1153 PF06627.11 EMT49938.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) RHS_repeat PF05593.14 EMT49941.1 - 7.1e-11 42.4 54.4 0.00017 22.0 0.2 11.3 10 2 3 13 13 13 7 RHS Repeat SPARC_Ca_bdg PF10591.9 EMT49942.1 - 0.033 14.5 0.3 0.063 13.6 0.2 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Transposase_20 PF02371.16 EMT49944.1 - 5.2e-07 29.9 0.0 6.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family Transposase_mut PF00872.18 EMT49945.1 - 6.3e-15 54.9 0.0 7.6e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family EFG_C PF00679.24 EMT49945.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 1 0 1 1 1 0 Elongation factor G C-terminus Glucosaminidase PF01832.20 EMT49947.1 - 0.1 13.1 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase HTH_28 PF13518.6 EMT49949.1 - 0.0043 17.1 0.0 4.6 7.4 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain rve PF00665.26 EMT49950.1 - 3.8e-21 75.5 0.0 9.9e-21 74.1 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_2 PF13333.6 EMT49950.1 - 2.3e-17 62.9 0.2 5.1e-17 61.8 0.2 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EMT49950.1 - 8.2e-13 47.9 0.0 2.7e-12 46.3 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 EMT49950.1 - 1.5e-10 41.0 1.5 4.4e-10 39.6 1.5 1.8 1 0 0 1 1 1 1 HTH-like domain DUF155 PF02582.14 EMT49950.1 - 0.044 13.9 0.9 0.43 10.6 0.5 2.3 2 1 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 DEDD_Tnp_IS110 PF01548.17 EMT49951.1 - 5.7e-24 84.7 0.6 8.4e-24 84.2 0.1 1.5 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.16 EMT49951.1 - 2e-17 63.3 0.0 4.5e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family MetOD2 PF18548.1 EMT49951.1 - 0.007 16.4 0.5 0.02 15.0 0.5 1.7 1 0 0 1 1 1 1 Metanogen output domain 2 HhH-GPD PF00730.25 EMT49951.1 - 0.017 15.6 0.0 0.26 11.7 0.0 2.7 2 1 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein PHP PF02811.19 EMT49951.1 - 0.086 13.1 0.1 0.17 12.2 0.1 1.4 1 1 0 1 1 1 0 PHP domain Resolvase PF00239.21 EMT49952.1 - 2.2e-24 86.2 0.5 2.9e-24 85.8 0.5 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain Recombinase PF07508.13 EMT49952.1 - 6.8e-10 39.3 0.1 3e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Recombinase HTH_32 PF13565.6 EMT49952.1 - 0.00015 22.3 0.3 0.00078 20.0 0.1 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_WhiA PF02650.14 EMT49952.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 WhiA C-terminal HTH domain IstB_IS21 PF01695.17 EMT49953.1 - 4.8e-09 36.2 0.0 9.9e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein PIF1 PF05970.14 EMT49953.1 - 0.015 14.5 0.2 0.12 11.5 0.1 1.9 2 0 0 2 2 2 0 PIF1-like helicase zf-CRD PF17979.1 EMT49953.1 - 0.062 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Kinesin PF00225.23 EMT49953.1 - 0.1 11.5 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 Kinesin motor domain DUF2791 PF10923.8 EMT49953.1 - 0.19 10.5 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) HTH_36 PF13730.6 EMT49955.1 - 6.9e-12 45.1 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 EMT49955.1 - 1.7e-07 31.1 0.1 4.1e-07 29.8 0.1 1.7 1 1 0 1 1 1 1 MarR family LexA_DNA_bind PF01726.16 EMT49955.1 - 8.7e-06 25.4 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 LexA DNA binding domain MarR_2 PF12802.7 EMT49955.1 - 1.2e-05 25.1 0.0 8.1e-05 22.4 0.0 2.1 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 EMT49955.1 - 1.2e-05 25.1 0.0 5.5e-05 23.1 0.0 1.8 1 1 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_5 PF01022.20 EMT49955.1 - 0.0003 20.6 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 EMT49955.1 - 0.00031 20.9 0.0 0.00069 19.8 0.0 1.7 2 0 0 2 2 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 EMT49955.1 - 0.00053 19.5 0.0 0.0039 16.7 0.0 2.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 EMT49955.1 - 0.00054 19.6 0.0 0.0016 18.1 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_12 PF08461.10 EMT49955.1 - 0.00077 19.4 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease R winged-helix domain TrmB PF01978.19 EMT49955.1 - 0.00086 19.1 0.0 0.0023 17.8 0.0 1.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 EMT49955.1 - 0.0071 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_34 PF13601.6 EMT49955.1 - 0.0077 16.4 0.1 0.042 14.0 0.0 2.3 3 0 0 3 3 3 1 Winged helix DNA-binding domain HTH_27 PF13463.6 EMT49955.1 - 0.0089 16.5 0.0 0.058 13.9 0.0 2.1 1 1 1 2 2 2 1 Winged helix DNA-binding domain HTH_20 PF12840.7 EMT49955.1 - 0.022 14.8 0.0 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Rrf2 PF02082.20 EMT49955.1 - 0.024 15.0 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_1 PF00126.27 EMT49955.1 - 0.079 12.9 0.0 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family PTS_2-RNA PF01885.16 EMT49957.1 - 1.6e-32 113.0 0.1 1.9e-32 112.8 0.1 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family COX16 PF14138.6 EMT49958.1 - 0.08 13.5 0.2 0.4 11.2 0.0 2.1 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 RHS_repeat PF05593.14 EMT49959.1 - 2.9e-07 30.8 12.6 8.8e-05 22.9 0.2 4.4 3 1 0 4 4 4 3 RHS Repeat MerR-DNA-bind PF09278.11 EMT49960.1 - 0.062 13.8 1.3 0.14 12.7 1.3 1.6 1 0 0 1 1 1 0 MerR, DNA binding RIX1 PF08167.12 EMT49960.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Flp_Fap PF04964.14 EMT49961.1 - 7.6e-09 35.3 0.7 8.8e-09 35.1 0.7 1.1 1 0 0 1 1 1 1 Flp/Fap pilin component Flp1_like PF16982.5 EMT49961.1 - 0.045 13.1 0.8 0.11 12.0 0.8 1.7 1 1 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Peptidase_A24 PF01478.18 EMT49962.1 - 1.5e-11 44.6 14.8 1.5e-11 44.6 14.8 1.6 2 1 0 2 2 2 1 Type IV leader peptidase family TadE PF07811.12 EMT49963.1 - 2.8e-13 49.9 2.0 4.4e-13 49.3 2.0 1.3 1 0 0 1 1 1 1 TadE-like protein ZT_dimer PF16916.5 EMT49963.1 - 0.023 14.8 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter Tad PF13400.6 EMT49963.1 - 0.44 10.9 4.9 1.9 8.9 4.9 2.0 1 1 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Tad PF13400.6 EMT49964.1 - 1.8e-10 40.9 0.8 2.8e-10 40.4 0.4 1.5 2 0 0 2 2 2 1 Putative Flp pilus-assembly TadE/G-like TadE PF07811.12 EMT49964.1 - 0.00032 20.9 3.9 0.00052 20.2 3.9 1.4 1 0 0 1 1 1 1 TadE-like protein Tad_C PF09977.9 EMT49964.1 - 0.0094 17.2 0.3 0.021 16.1 0.3 1.7 1 1 0 1 1 1 1 Putative Tad-like Flp pilus-assembly Fumarate_red_D PF02313.17 EMT49964.1 - 0.11 12.6 0.3 0.22 11.7 0.3 1.4 1 0 0 1 1 1 0 Fumarate reductase subunit D UPF0259 PF06790.11 EMT49965.1 - 0.0019 18.0 11.4 0.0026 17.5 11.4 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0259) DUF192 PF02643.15 EMT49966.1 - 2.5e-20 72.4 0.0 2.9e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 AAA PF00004.29 EMT49967.1 - 2.7e-40 137.8 0.0 4.3e-19 69.2 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EMT49967.1 - 3.7e-26 91.1 9.3 2.2e-14 53.4 1.0 3.8 3 0 0 3 3 3 2 AAA lid domain RuvB_N PF05496.12 EMT49967.1 - 4e-12 46.2 0.9 0.00019 21.2 0.1 3.9 3 2 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EMT49967.1 - 1.5e-11 45.0 5.6 0.0081 16.6 0.0 5.1 4 2 0 4 4 4 3 AAA ATPase domain AAA_22 PF13401.6 EMT49967.1 - 4.1e-11 43.3 2.1 0.071 13.4 0.1 6.0 5 1 0 5 5 4 2 AAA domain AAA_5 PF07728.14 EMT49967.1 - 1.1e-10 41.6 0.2 0.056 13.4 0.0 4.2 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMT49967.1 - 4.5e-10 39.3 2.4 0.017 14.5 0.1 5.3 3 2 2 5 5 5 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EMT49967.1 - 1.6e-08 34.4 0.8 0.02 14.6 0.1 5.0 4 2 0 4 4 3 2 Sigma-54 interaction domain AAA_30 PF13604.6 EMT49967.1 - 5.7e-08 32.7 1.4 0.0023 17.7 0.3 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EMT49967.1 - 2e-07 31.6 0.1 0.031 14.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain Torsin PF06309.11 EMT49967.1 - 2.5e-07 30.9 0.0 0.0011 19.1 0.0 3.1 3 0 0 3 3 3 2 Torsin AAA_19 PF13245.6 EMT49967.1 - 1e-06 29.2 1.4 0.25 11.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain DUF815 PF05673.13 EMT49967.1 - 1.8e-06 27.3 0.6 0.27 10.4 0.0 4.6 5 0 0 5 5 5 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EMT49967.1 - 4.2e-06 27.1 0.0 0.11 12.9 0.0 3.4 3 0 0 3 3 3 2 RNA helicase NTPase_1 PF03266.15 EMT49967.1 - 5.7e-06 26.4 0.2 0.027 14.4 0.2 3.0 3 0 0 3 3 3 2 NTPase AAA_7 PF12775.7 EMT49967.1 - 7.8e-06 25.5 0.2 2.4 7.6 0.0 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_33 PF13671.6 EMT49967.1 - 2.4e-05 24.5 1.2 0.14 12.3 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_2 PF07724.14 EMT49967.1 - 3.2e-05 24.1 0.0 0.39 10.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 EMT49967.1 - 6.1e-05 23.0 0.3 0.53 10.2 0.1 3.1 2 0 0 2 2 2 2 NACHT domain Zeta_toxin PF06414.12 EMT49967.1 - 0.00018 20.8 0.1 4.2 6.6 0.0 3.6 3 0 0 3 3 3 0 Zeta toxin AAA_11 PF13086.6 EMT49967.1 - 0.00021 21.2 1.9 0.25 11.1 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 EMT49967.1 - 0.00025 21.4 1.7 1.1 9.5 0.0 4.0 4 0 0 4 4 2 2 AAA domain TsaE PF02367.17 EMT49967.1 - 0.00026 21.0 1.3 0.52 10.3 0.0 3.1 4 0 0 4 4 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EMT49967.1 - 0.0007 19.4 0.0 0.85 9.3 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase SKI PF01202.22 EMT49967.1 - 0.0007 19.7 0.8 0.11 12.6 0.0 3.0 3 0 0 3 3 3 1 Shikimate kinase AAA_3 PF07726.11 EMT49967.1 - 0.0012 18.7 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EMT49967.1 - 0.0014 19.2 0.4 2.9 8.4 0.0 3.2 3 0 0 3 3 3 1 ABC transporter TrwB_AAD_bind PF10412.9 EMT49967.1 - 0.0018 17.3 2.5 1.9 7.3 0.1 4.1 4 0 0 4 4 4 1 Type IV secretion-system coupling protein DNA-binding domain APS_kinase PF01583.20 EMT49967.1 - 0.0019 18.1 0.2 1.6 8.6 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_17 PF13207.6 EMT49967.1 - 0.0021 18.5 0.4 2.6 8.5 0.1 3.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EMT49967.1 - 0.0022 18.0 0.1 4.4 7.3 0.0 3.9 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit MCM PF00493.23 EMT49967.1 - 0.0028 16.8 0.2 0.28 10.2 0.0 2.5 2 0 0 2 2 2 1 MCM P-loop domain DUF2075 PF09848.9 EMT49967.1 - 0.0033 16.7 0.0 2.7 7.1 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 EMT49967.1 - 0.0055 16.8 0.0 1.4 9.0 0.0 3.5 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 EMT49967.1 - 0.0098 15.6 0.0 11 5.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EMT49967.1 - 0.016 14.3 0.0 27 3.7 0.0 3.3 3 0 0 3 3 3 0 Type II/IV secretion system protein NB-ARC PF00931.22 EMT49967.1 - 0.019 14.2 0.6 5.4 6.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DNA_pol3_delta2 PF13177.6 EMT49967.1 - 0.027 14.3 0.0 8.5 6.1 0.0 3.6 4 0 0 4 4 4 0 DNA polymerase III, delta subunit TIP49 PF06068.13 EMT49967.1 - 0.033 13.4 3.1 20 4.3 0.1 4.4 4 1 0 5 5 5 0 TIP49 P-loop domain KTI12 PF08433.10 EMT49967.1 - 0.034 13.6 0.0 7.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CbiA PF01656.23 EMT49967.1 - 0.036 14.1 0.2 11 6.1 0.0 2.9 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 EMT49967.1 - 0.057 13.1 0.2 17 5.0 0.0 2.9 2 0 0 2 2 2 0 Thymidylate kinase ATPase PF06745.13 EMT49967.1 - 0.065 12.6 0.3 8.8 5.6 0.0 3.3 4 0 0 4 4 4 0 KaiC IstB_IS21 PF01695.17 EMT49967.1 - 0.071 12.8 0.2 14 5.3 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 EMT49967.1 - 0.1 12.2 6.1 6.7 6.2 0.0 4.8 3 1 2 5 5 5 0 AAA domain PhoH PF02562.16 EMT49967.1 - 0.12 11.9 0.3 7.2 6.0 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein DUF853 PF05872.12 EMT49967.1 - 0.14 10.7 2.9 3.5 6.1 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) cobW PF02492.19 EMT49967.1 - 0.15 11.6 0.3 7.2 6.2 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Asp-Al_Ex PF06826.12 EMT49968.1 - 0.0043 16.9 2.7 0.0043 16.9 2.7 1.6 1 1 1 2 2 2 1 Predicted Permease Membrane Region Phage_holin_2_1 PF04971.12 EMT49968.1 - 0.089 12.8 5.5 0.082 12.9 1.1 2.2 2 0 0 2 2 2 0 Bacteriophage P21 holin S FtsK_SpoIIIE PF01580.18 EMT49969.1 - 9.4e-05 21.9 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 EMT49969.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain WG_beta_rep PF14903.6 EMT49970.1 - 2.8e-22 78.6 0.8 4.3e-12 46.1 0.1 4.0 3 1 1 4 4 4 3 WG containing repeat Big_2 PF02368.18 EMT49970.1 - 2.4e-06 27.3 1.1 9.6e-06 25.4 0.2 2.3 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 2) RR_TM4-6 PF06459.12 EMT49970.1 - 0.84 9.4 5.2 1.2 8.8 5.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLH PF00395.20 EMT49971.1 - 9.2e-14 51.2 0.1 1.5e-06 28.1 0.0 3.7 3 0 0 3 3 3 3 S-layer homology domain APH PF01636.23 EMT49972.1 - 6.6e-30 104.8 0.3 1e-29 104.2 0.2 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EMT49972.1 - 2.8e-05 23.5 0.1 0.056 12.6 0.0 2.1 2 0 0 2 2 2 2 Fructosamine kinase DUF1679 PF07914.11 EMT49972.1 - 4.3e-05 22.6 0.0 0.0001 21.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EMT49972.1 - 0.00014 21.5 0.0 0.0042 16.7 0.0 2.1 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EMT49972.1 - 0.0021 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 EMT49972.1 - 0.039 13.3 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EMT49972.1 - 0.11 12.1 0.0 4.8 6.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Peripla_BP_4 PF13407.6 EMT49973.1 - 3.7e-38 131.6 10.6 4.4e-38 131.3 10.6 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 EMT49973.1 - 9.4e-13 48.2 0.6 1.3e-12 47.8 0.6 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 EMT49973.1 - 1.9e-10 41.3 0.0 1.5e-08 35.2 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Lipid_DES PF08557.10 EMT49973.1 - 0.12 11.9 0.5 6.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) Chorion_3 PF05387.11 EMT49973.1 - 0.36 10.4 4.4 7.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Chorion family 3 ABC_tran PF00005.27 EMT49974.1 - 1.3e-46 158.6 0.0 5.5e-24 85.2 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMT49974.1 - 1.8e-09 37.9 0.6 0.0027 17.6 0.0 3.8 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EMT49974.1 - 2.2e-05 24.3 1.0 0.0049 16.6 0.3 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMT49974.1 - 9.7e-05 22.7 0.4 0.7 10.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EMT49974.1 - 0.0001 22.7 0.6 0.12 12.8 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EMT49974.1 - 0.00012 21.6 0.3 0.29 10.5 0.0 2.9 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMT49974.1 - 0.00037 20.5 0.1 0.063 13.2 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 EMT49974.1 - 0.00038 20.2 0.5 3.1 7.5 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein MMR_HSR1 PF01926.23 EMT49974.1 - 0.0006 19.9 0.0 0.31 11.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EMT49974.1 - 0.0008 19.1 0.2 0.0067 16.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EMT49974.1 - 0.0056 16.8 1.0 4.2 7.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EMT49974.1 - 0.0058 16.2 0.0 0.022 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EMT49974.1 - 0.0064 15.8 0.7 1.2 8.4 0.2 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 EMT49974.1 - 0.0076 16.8 0.9 4.3 7.9 0.0 2.8 2 1 1 3 3 3 1 AAA domain Ploopntkinase3 PF18751.1 EMT49974.1 - 0.012 15.6 0.1 0.56 10.1 0.0 2.6 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 EMT49974.1 - 0.014 15.9 0.0 0.044 14.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EMT49974.1 - 0.019 14.5 0.2 0.74 9.4 0.1 3.1 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 EMT49974.1 - 0.02 14.9 0.3 9.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EMT49974.1 - 0.034 14.4 0.0 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EMT49974.1 - 0.065 12.8 0.5 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MukB PF04310.12 EMT49974.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 MukB N-terminal Dynamin_N PF00350.23 EMT49974.1 - 0.092 12.8 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 EMT49974.1 - 0.13 12.3 2.5 0.32 11.0 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain VirE PF05272.11 EMT49974.1 - 0.18 11.5 0.0 0.47 10.2 0.0 1.6 2 0 0 2 2 1 0 Virulence-associated protein E SbcCD_C PF13558.6 EMT49974.1 - 0.21 11.9 0.4 45 4.4 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit BPD_transp_2 PF02653.16 EMT49975.1 - 7.7e-42 143.3 36.2 1.1e-41 142.7 36.2 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component AcrZ PF10766.9 EMT49975.1 - 0.042 13.4 2.1 0.25 11.0 2.1 2.4 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ Catalase PF00199.19 EMT49976.1 - 1.1e-174 581.1 0.5 1.3e-174 580.8 0.5 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EMT49976.1 - 1.3e-23 83.0 0.2 6.1e-22 77.6 0.0 2.5 2 0 0 2 2 2 1 Catalase-related immune-responsive YqzH PF14164.6 EMT49976.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 YqzH-like protein AAA PF00004.29 EMT49977.1 - 6.5e-38 130.2 0.0 1.1e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMT49977.1 - 2.4e-10 40.0 0.0 4.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EMT49977.1 - 9.5e-05 22.8 0.7 0.0032 17.9 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EMT49977.1 - 0.00016 21.4 0.0 0.00053 19.8 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EMT49977.1 - 0.001 19.2 0.0 0.011 15.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EMT49977.1 - 0.0014 18.7 0.0 0.0054 16.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EMT49977.1 - 0.006 16.6 0.0 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMT49977.1 - 0.019 15.1 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EMT49977.1 - 0.033 14.4 0.3 0.18 12.1 0.2 2.2 1 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 EMT49977.1 - 0.036 14.2 0.0 0.16 12.1 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 EMT49977.1 - 0.069 13.7 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EMT49977.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_16 PF13432.6 EMT49977.1 - 0.096 13.4 0.1 0.22 12.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Mg_chelatase PF01078.21 EMT49977.1 - 0.1 12.0 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EMT49977.1 - 0.12 12.8 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 EMT49977.1 - 0.13 11.8 0.3 0.29 10.7 0.3 1.5 1 0 0 1 1 1 0 AAA domain Cwf_Cwc_15 PF04889.12 EMT49977.1 - 1.2 8.8 10.5 1 9.0 9.2 1.5 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 EMT49977.1 - 1.7 9.1 9.3 3 8.3 9.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_2 PF07719.17 EMT49978.1 - 1e-24 84.6 17.5 2.5e-07 30.3 0.8 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 EMT49978.1 - 8.5e-23 78.6 16.2 1.5e-05 24.8 0.3 7.5 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 EMT49978.1 - 2.5e-19 68.2 12.7 9.7e-07 28.4 0.4 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EMT49978.1 - 1.3e-18 66.0 6.0 0.00099 19.7 1.0 7.7 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMT49978.1 - 2.3e-18 66.5 6.9 2.6e-06 27.8 0.4 5.6 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EMT49978.1 - 2.2e-15 56.1 11.4 5e-06 26.1 4.8 5.6 4 1 1 5 5 5 3 TPR repeat TPR_9 PF13371.6 EMT49978.1 - 5.9e-15 55.2 3.1 3e-05 24.1 0.1 5.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EMT49978.1 - 1.5e-14 54.0 10.6 0.001 19.3 1.2 5.0 3 2 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 EMT49978.1 - 1.6e-14 54.3 7.3 0.00011 22.8 5.7 5.2 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 EMT49978.1 - 1.1e-12 47.4 2.5 0.25 11.8 0.0 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EMT49978.1 - 7.9e-11 42.0 6.0 0.007 16.6 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EMT49978.1 - 4.7e-09 35.6 7.8 0.015 15.3 0.4 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EMT49978.1 - 6.7e-09 35.8 13.0 0.029 15.0 0.3 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 EMT49978.1 - 1e-05 25.2 17.4 0.066 13.1 2.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EMT49978.1 - 0.00041 19.7 4.6 0.012 14.8 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 EMT49978.1 - 0.0017 18.1 0.7 0.019 14.6 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 EMT49978.1 - 0.0018 18.5 1.7 0.71 10.2 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF4919 PF16266.5 EMT49978.1 - 0.0034 17.4 4.6 0.43 10.5 0.1 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4919) Coatomer_E PF04733.14 EMT49978.1 - 0.0081 15.6 0.3 0.049 13.0 0.0 2.2 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_4 PF07721.14 EMT49978.1 - 0.022 15.4 0.3 7.9 7.4 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMT49978.1 - 0.053 13.6 8.2 18 5.5 0.3 5.8 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 EMT49978.1 - 0.069 12.6 0.6 3.1 7.3 0.0 3.2 3 0 0 3 3 3 0 SHNi-TPR DUF627 PF04781.12 EMT49978.1 - 0.076 13.0 0.3 3.9 7.5 0.0 3.4 4 1 0 4 4 4 0 Protein of unknown function (DUF627) DUF4810 PF16068.5 EMT49978.1 - 0.077 13.6 3.1 55 4.4 0.0 4.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4810) HemY_N PF07219.13 EMT49978.1 - 0.57 10.4 2.0 14 6.0 0.0 3.0 3 0 0 3 3 2 0 HemY protein N-terminus TPR_3 PF07720.12 EMT49978.1 - 2.2 8.4 11.4 4.3 7.4 0.4 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EMT49978.1 - 6.4 6.9 11.8 43 4.3 0.0 5.2 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain GYF_2 PF14237.6 EMT49979.1 - 2.1e-07 30.6 1.3 3.6e-07 29.9 1.3 1.4 1 0 0 1 1 1 1 GYF domain 2 CNTF PF01110.17 EMT49979.1 - 0.066 12.6 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor Arginase PF00491.21 EMT49980.1 - 2.9e-82 276.3 0.3 3.4e-82 276.1 0.3 1.0 1 0 0 1 1 1 1 Arginase family SpoOE-like PF09388.10 EMT49981.1 - 5.1e-09 35.9 1.0 6.7e-09 35.5 1.0 1.2 1 0 0 1 1 1 1 Spo0E like sporulation regulatory protein Mod_r PF07200.13 EMT49981.1 - 0.019 15.0 0.2 0.02 15.0 0.2 1.0 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Takusan PF04822.13 EMT49981.1 - 0.047 13.6 0.6 0.056 13.3 0.6 1.2 1 0 0 1 1 1 0 Takusan IF-2B PF01008.17 EMT49981.1 - 0.11 11.7 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Initiation factor 2 subunit family Sigma70_r2 PF04542.14 EMT49982.1 - 1e-21 76.4 0.7 2.1e-21 75.4 0.3 1.7 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT49982.1 - 1.1e-15 57.0 0.2 2.6e-15 55.8 0.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT49982.1 - 2.9e-11 42.7 0.3 6.3e-11 41.6 0.3 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_16 PF12645.7 EMT49982.1 - 1.5e-06 28.2 0.9 3.7e-06 26.9 0.4 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 EMT49982.1 - 2.4e-05 24.3 0.6 0.00033 20.6 0.6 2.0 1 1 0 1 1 1 1 ECF sigma factor UPF0122 PF04297.14 EMT49982.1 - 0.0052 17.0 0.3 0.015 15.6 0.1 1.9 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like zf-HC2 PF13490.6 EMT49983.1 - 1.9e-08 34.4 0.3 3.8e-08 33.4 0.3 1.6 1 0 0 1 1 1 1 Putative zinc-finger Bactofilin PF04519.13 EMT49983.1 - 5.3e-07 29.8 1.0 8.9e-07 29.1 1.0 1.3 1 0 0 1 1 1 1 Polymer-forming cytoskeletal Med20 PF08612.11 EMT49983.1 - 0.0041 16.5 0.7 0.0052 16.2 0.7 1.4 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex MYO10_CC PF16735.5 EMT49983.1 - 0.077 13.1 0.6 0.13 12.3 0.6 1.3 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain ThrE PF06738.12 EMT49983.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF3379 PF11859.8 EMT49983.1 - 0.11 11.8 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) DisA_N PF02457.16 EMT49984.1 - 1.4e-43 147.3 0.3 2.2e-43 146.6 0.3 1.3 1 0 0 1 1 1 1 DisA bacterial checkpoint controller nucleotide-binding TPM_phosphatase PF04536.14 EMT49984.1 - 0.0085 16.3 0.0 0.059 13.5 0.0 2.0 2 0 0 2 2 2 1 TPM domain FANCI_S1-cap PF14674.6 EMT49984.1 - 0.37 10.9 3.9 0.82 9.8 0.1 3.0 3 0 0 3 3 3 0 FANCI solenoid 1 cap YbbR PF07949.12 EMT49985.1 - 1.4e-25 89.4 24.0 6.5e-11 42.4 4.6 4.6 4 0 0 4 4 4 4 YbbR-like protein PGM_PMM_I PF02878.16 EMT49986.1 - 2.2e-43 147.3 0.0 4.6e-43 146.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EMT49986.1 - 6.1e-34 116.6 0.2 1.2e-33 115.7 0.2 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EMT49986.1 - 6e-18 64.8 2.2 1.7e-17 63.4 2.2 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 EMT49986.1 - 1.9e-16 60.5 0.0 4.5e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II CinA_KH PF18146.1 EMT49986.1 - 0.22 11.7 3.8 0.17 12.1 0.4 2.6 3 1 1 4 4 4 0 Damage-inducible protein CinA KH domain SIS PF01380.22 EMT49987.1 - 4e-56 188.4 1.0 4.8e-31 107.3 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EMT49987.1 - 4.4e-22 78.7 0.0 9.2e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EMT49987.1 - 5.1e-17 61.9 0.0 2e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain SIS_2 PF13580.6 EMT49987.1 - 9.5e-05 22.4 0.0 0.00025 21.1 0.0 1.7 1 0 0 1 1 1 1 SIS domain GATase_4 PF13230.6 EMT49987.1 - 0.0003 19.8 0.0 0.00046 19.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II zf-HC2 PF13490.6 EMT49987.1 - 0.26 11.6 2.3 4.7 7.5 0.1 3.6 4 0 0 4 4 4 0 Putative zinc-finger ABC_tran PF00005.27 EMT49988.1 - 5.1e-33 114.5 0.0 8.3e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT49988.1 - 1.6e-05 24.9 0.1 0.031 14.1 0.2 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT49988.1 - 2.5e-05 23.9 0.1 4.7e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT49988.1 - 6e-05 23.5 0.0 0.0001 22.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EMT49988.1 - 0.00013 22.6 0.1 0.00021 21.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EMT49988.1 - 0.00015 21.3 0.0 0.0018 17.7 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 EMT49988.1 - 0.0012 18.8 0.0 0.21 11.5 0.1 2.3 2 1 0 2 2 2 1 NTPase T2SSE PF00437.20 EMT49988.1 - 0.002 17.2 0.0 0.0038 16.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EMT49988.1 - 0.003 17.3 0.0 0.015 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT49988.1 - 0.0075 16.2 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 EMT49988.1 - 0.0097 16.3 0.1 0.084 13.3 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMT49988.1 - 0.012 15.9 0.1 0.091 13.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EMT49988.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 EMT49988.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 EMT49988.1 - 0.025 14.5 0.1 0.088 12.7 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EMT49988.1 - 0.033 14.4 2.2 2.2 8.5 0.3 2.5 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 EMT49988.1 - 0.036 14.0 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 EMT49988.1 - 0.036 14.4 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EMT49988.1 - 0.047 13.4 0.0 0.22 11.2 0.0 2.0 2 1 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.19 EMT49988.1 - 0.05 13.2 0.2 0.096 12.3 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EMT49988.1 - 0.057 13.0 0.1 0.59 9.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMT49988.1 - 0.07 13.7 0.0 0.6 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EMT49988.1 - 0.095 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EMT49988.1 - 0.11 11.6 0.1 0.21 10.7 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 EMT49988.1 - 0.12 12.1 0.1 0.62 9.8 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.18 EMT49988.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EMT49988.1 - 0.17 11.6 0.1 0.4 10.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMT49988.1 - 0.19 12.1 0.0 0.9 10.0 0.0 2.0 2 0 0 2 2 2 0 RNA helicase FtsX PF02687.21 EMT49989.1 - 1e-08 35.5 21.7 1.5e-08 35.0 11.6 5.6 5 1 0 5 5 5 2 FtsX-like permease family Response_reg PF00072.24 EMT49990.1 - 2.8e-29 101.5 0.1 5.5e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT49990.1 - 3.3e-20 72.0 1.0 1.6e-19 69.8 0.8 2.2 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal B12-binding PF02310.19 EMT49990.1 - 0.075 13.1 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 B12 binding domain Peripla_BP_6 PF13458.6 EMT49990.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Rrf2 PF02082.20 EMT49990.1 - 0.13 12.6 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HATPase_c PF02518.26 EMT49991.1 - 3.3e-10 40.4 0.0 5.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT49991.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF2518 PF10726.9 EMT49991.1 - 0.53 9.9 5.7 6.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of function (DUF2518) DUF92 PF01940.16 EMT49992.1 - 3.3e-65 219.8 6.8 4e-65 219.5 6.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Sgf11 PF08209.11 EMT49992.1 - 0.053 13.1 1.0 0.15 11.6 1.0 1.8 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) zinc-ribbons_6 PF07191.12 EMT49992.1 - 0.057 13.4 0.2 0.096 12.7 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbons zf-ribbon_3 PF13248.6 EMT49992.1 - 0.11 11.9 0.4 0.21 11.1 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EMT49992.1 - 0.23 11.6 0.9 0.47 10.6 0.9 1.5 1 1 0 1 1 1 0 Zinc ribbon domain Desulfoferrod_N PF06397.12 EMT49992.1 - 0.27 10.9 1.8 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF2306 PF10067.9 EMT49993.1 - 2.4e-31 108.9 14.0 2.4e-31 108.9 14.0 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 EMT49993.1 - 8.3e-09 35.8 8.4 1.6e-06 28.5 2.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF420) TetR_N PF00440.23 EMT49994.1 - 7.4e-12 44.9 0.1 1.3e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 EMT49994.1 - 1.9e-07 31.0 0.0 3.9e-07 30.0 0.0 1.5 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_17 PF17922.1 EMT49994.1 - 5e-07 29.7 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 EMT49994.1 - 0.0007 19.8 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_36 PF18598.1 EMT49994.1 - 0.0016 18.4 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 EMT49994.1 - 0.012 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_IclR PF09339.10 EMT49994.1 - 0.041 13.7 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain TetR_C_24 PF17932.1 EMT49994.1 - 0.07 13.4 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_25 PF17933.1 EMT49994.1 - 0.094 13.1 0.2 0.36 11.2 0.1 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 EMT49996.1 - 2.3e-40 138.6 53.3 3.2e-30 105.3 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT49996.1 - 6e-14 51.8 42.4 5.7e-10 38.6 18.0 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EMT49996.1 - 3.9e-06 25.7 29.4 0.00034 19.3 11.7 2.7 1 1 2 3 3 3 2 MFS/sugar transport protein LysR_substrate PF03466.20 EMT49997.1 - 2.3e-42 144.7 0.0 3.1e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT49997.1 - 8e-21 73.8 0.2 1.4e-20 72.9 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EMT49997.1 - 0.031 14.1 0.1 0.073 12.9 0.1 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_5 PF01022.20 EMT49997.1 - 0.081 12.8 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 EMT49997.1 - 0.1 12.6 0.1 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 HTH domain MarR_2 PF12802.7 EMT49997.1 - 0.14 12.0 0.4 0.51 10.3 0.1 2.1 2 0 0 2 2 2 0 MarR family MFS_1 PF07690.16 EMT49998.1 - 2.8e-40 138.4 50.3 8.5e-29 100.6 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT49998.1 - 8.9e-11 41.3 22.2 4.2e-07 29.2 8.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 EMT49998.1 - 5.5e-09 35.0 5.8 5.5e-09 35.0 5.8 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector PTR2 PF00854.21 EMT49998.1 - 3.6e-05 22.8 4.4 0.053 12.3 0.1 2.6 2 1 0 2 2 2 2 POT family ASCH PF04266.14 EMT49999.1 - 0.00014 22.4 0.1 0.00017 22.1 0.1 1.2 1 0 0 1 1 1 1 ASCH domain Rhamno_transf PF11316.8 EMT50000.1 - 2.5e-12 46.7 0.1 3.9e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Putative rhamnosyl transferase Glycos_transf_2 PF00535.26 EMT50000.1 - 0.002 18.0 0.2 0.004 17.0 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 DUF1460 PF07313.12 EMT50000.1 - 0.067 12.6 5.7 0.035 13.5 3.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1460) Response_reg PF00072.24 EMT50001.1 - 1.1e-24 86.8 0.4 2.4e-24 85.6 0.1 1.7 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT50001.1 - 5.3e-19 68.1 0.1 9.6e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal PhaC_N PF07167.13 EMT50001.1 - 0.048 13.3 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus HATPase_c PF02518.26 EMT50002.1 - 1.3e-19 70.7 0.2 2.5e-19 69.8 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMT50002.1 - 3.9e-05 23.5 0.0 7.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT50002.1 - 0.00016 21.6 0.0 0.00067 19.6 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 EMT50002.1 - 0.013 15.3 0.7 0.045 13.7 0.1 2.1 2 0 0 2 2 2 0 GHKL domain HisKA PF00512.25 EMT50002.1 - 0.057 13.5 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain CreD PF06123.12 EMT50002.1 - 0.75 8.5 4.3 1.1 7.9 4.3 1.3 1 0 0 1 1 1 0 Inner membrane protein CreD ABC_tran PF00005.27 EMT50003.1 - 4.2e-32 111.5 0.0 5.8e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT50003.1 - 8.6e-11 42.2 0.8 4.9e-06 26.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT50003.1 - 7.9e-05 22.2 0.7 0.00054 19.5 0.7 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMT50003.1 - 0.00013 21.9 0.1 0.0009 19.2 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 EMT50003.1 - 0.0018 17.4 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 EMT50003.1 - 0.0027 18.2 1.1 0.0056 17.2 1.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT50003.1 - 0.0033 17.8 0.0 0.0044 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT50003.1 - 0.0041 17.4 0.1 0.1 12.8 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.6 EMT50003.1 - 0.0057 16.4 0.3 0.011 15.5 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EMT50003.1 - 0.0064 17.0 0.0 0.023 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EMT50003.1 - 0.011 15.8 0.4 0.031 14.4 0.4 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EMT50003.1 - 0.032 14.5 0.0 0.11 12.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 EMT50003.1 - 0.033 13.8 0.1 0.077 12.6 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 EMT50003.1 - 0.039 13.4 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 EMT50003.1 - 0.041 13.5 0.0 0.76 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMT50003.1 - 0.079 12.7 0.0 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EMT50003.1 - 0.094 12.5 0.2 0.75 9.5 0.1 2.1 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Rad17 PF03215.15 EMT50003.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 EMT50003.1 - 0.11 13.0 0.8 1.1 9.7 0.8 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 EMT50003.1 - 0.12 12.4 0.2 0.18 11.8 0.2 1.6 1 1 0 1 1 1 0 Dynamin family PhoH PF02562.16 EMT50003.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 EMT50003.1 - 0.15 11.8 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EMT50003.1 - 0.17 11.1 0.1 0.31 10.2 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain FtsX PF02687.21 EMT50004.1 - 1.6e-06 28.5 4.6 1.6e-06 28.5 4.6 5.5 5 1 0 5 5 5 3 FtsX-like permease family Wzz PF02706.15 EMT50004.1 - 0.45 10.9 3.8 1.4 9.3 0.1 3.4 3 0 0 3 3 3 0 Chain length determinant protein YitT_membrane PF02588.15 EMT50005.1 - 2.8e-06 26.9 16.0 0.00014 21.3 8.5 2.1 1 1 1 2 2 2 2 Uncharacterised 5xTM membrane BCR, YitT family COG1284 rve PF00665.26 EMT50006.1 - 2.1e-19 69.9 0.0 2.8e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 EMT50006.1 - 8.9e-15 54.6 0.6 1.4e-14 53.9 0.6 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EMT50006.1 - 4.2e-13 48.9 0.0 6.7e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EMT50006.1 - 0.005 17.1 0.1 0.0057 16.9 0.1 1.1 1 0 0 1 1 1 1 DDE domain HTH_33 PF13592.6 EMT50006.1 - 0.03 14.0 0.6 8.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix rve PF00665.26 EMT50007.1 - 1.9e-17 63.5 0.0 2.5e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 EMT50007.1 - 8.2e-15 54.7 0.6 1.3e-14 54.0 0.6 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EMT50007.1 - 3.8e-13 49.0 0.0 6.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EMT50007.1 - 0.0093 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 DDE domain HTH_33 PF13592.6 EMT50007.1 - 0.024 14.3 0.4 7.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix DUF2633 PF11119.8 EMT50008.1 - 0.14 12.1 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Cu-oxidase_3 PF07732.15 EMT50009.1 - 1.2e-37 128.5 6.6 1.3e-32 112.3 0.6 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMT50009.1 - 5.2e-30 104.0 11.7 1.5e-23 83.1 4.4 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EMT50009.1 - 9.2e-19 68.1 0.9 2.1e-08 34.4 0.1 3.4 2 1 1 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 EMT50009.1 - 3.6e-06 27.0 0.1 0.0083 16.2 0.0 3.3 3 0 0 3 3 3 2 Cupredoxin-like domain UPF0093 PF03653.13 EMT50010.1 - 9.4e-07 29.2 8.6 1.5e-06 28.5 8.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) DUF2269 PF10027.9 EMT50010.1 - 2.2e-06 27.8 13.2 3.6e-06 27.1 13.2 1.5 1 1 0 1 1 1 1 Predicted integral membrane protein (DUF2269) SirB PF04247.12 EMT50010.1 - 0.49 10.5 16.5 11 6.2 16.6 2.5 1 1 0 1 1 1 0 Invasion gene expression up-regulator, SirB Response_reg PF00072.24 EMT50011.1 - 6.6e-30 103.6 0.0 1e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT50011.1 - 5.2e-27 93.7 0.1 1.5e-26 92.3 0.1 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal GerE PF00196.19 EMT50011.1 - 0.013 15.1 0.3 0.43 10.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family 3HCDH_RFF PF18321.1 EMT50011.1 - 0.019 15.4 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain HATPase_c PF02518.26 EMT50012.1 - 4.2e-25 88.4 0.0 1.4e-24 86.7 0.0 1.8 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT50012.1 - 2.1e-12 46.9 1.4 6.8e-12 45.3 0.8 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EMT50012.1 - 3.2e-07 30.6 0.0 6.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.6 EMT50012.1 - 0.00084 19.2 0.0 0.0017 18.2 0.0 1.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Afaf PF15339.6 EMT50012.1 - 0.23 11.2 0.3 0.4 10.4 0.3 1.4 1 0 0 1 1 1 0 Acrosome formation-associated factor ADH_zinc_N PF00107.26 EMT50013.1 - 7e-17 61.6 0.1 8e-17 61.4 0.1 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMT50013.1 - 3.9e-05 24.7 0.0 5.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMT50013.1 - 0.0013 18.0 0.1 0.0019 17.6 0.1 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EMT50013.1 - 0.13 12.7 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding Fic PF02661.18 EMT50014.1 - 1.2e-16 61.4 0.1 1.9e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 Fic/DOC family VbhA PF18495.1 EMT50015.1 - 0.00054 19.8 0.0 0.00073 19.3 0.0 1.2 1 0 0 1 1 1 1 Antitoxin VbhA Transposase_mut PF00872.18 EMT50017.1 - 5.1e-116 387.7 2.0 6.3e-116 387.4 2.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 EMT50017.1 - 0.0025 18.2 0.0 0.0056 17.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Bac_DNA_binding PF00216.21 EMT50017.1 - 2.2 8.5 4.3 5.6 7.2 0.7 2.5 2 0 0 2 2 2 0 Bacterial DNA-binding protein AAA_16 PF13191.6 EMT50018.1 - 0.00027 21.4 0.0 0.0033 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EMT50018.1 - 0.00043 19.6 1.0 0.31 10.2 0.0 3.1 2 1 1 3 3 3 2 NB-ARC domain AAA_14 PF13173.6 EMT50018.1 - 0.00055 20.0 0.0 0.0016 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMT50018.1 - 0.0076 16.5 0.0 0.048 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EMT50018.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 EMT50018.1 - 0.017 14.5 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 EMT50018.1 - 0.022 14.6 0.0 0.076 12.9 0.0 2.0 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 EMT50018.1 - 0.028 14.4 0.0 0.095 12.7 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 EMT50018.1 - 0.031 14.8 0.0 0.11 13.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 EMT50018.1 - 0.041 13.6 0.0 7.3 6.3 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF1539 PF07560.11 EMT50018.1 - 0.088 12.9 2.0 0.74 9.9 0.1 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) AAA_33 PF13671.6 EMT50018.1 - 0.18 12.0 0.0 0.66 10.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain NgoMIV_restric PF09015.10 EMT50019.1 - 0.051 12.7 0.1 0.069 12.3 0.1 1.2 1 0 0 1 1 1 0 NgoMIV restriction enzyme Tn7_Tnp_TnsA_N PF08722.11 EMT50019.1 - 0.059 13.6 0.4 0.18 12.0 0.1 1.9 1 1 1 2 2 2 0 TnsA endonuclease N terminal UvrD-helicase PF00580.21 EMT50020.1 - 1e-33 117.2 1.1 1.4e-30 106.9 0.0 3.1 2 2 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EMT50020.1 - 4e-29 102.1 2.0 1.1e-16 61.2 0.1 2.3 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EMT50020.1 - 4.2e-18 66.1 0.0 3.4e-17 63.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EMT50020.1 - 1.2e-07 31.4 0.0 3.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EMT50020.1 - 1.5e-05 24.9 0.0 0.0037 17.1 0.0 3.3 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EMT50020.1 - 0.0021 17.8 0.0 0.074 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EMT50021.1 - 8.5e-32 111.3 4.8 1.2e-29 104.3 4.8 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EMT50021.1 - 3.2e-18 66.6 0.2 5.4e-11 42.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMT50021.1 - 6.1e-10 39.9 2.1 7.3e-09 36.4 0.9 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EMT50021.1 - 4.2e-08 32.9 0.3 3.3e-07 30.0 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF2813 PF11398.8 EMT50021.1 - 6.4e-08 32.2 0.1 5.7e-07 29.1 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2813) AAA_29 PF13555.6 EMT50021.1 - 0.00018 21.1 0.1 0.00066 19.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EMT50021.1 - 0.0076 15.9 0.1 0.024 14.3 0.1 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EMT50021.1 - 0.033 14.7 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EMT50021.1 - 0.16 11.5 0.6 12 5.4 0.0 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region Resolvase PF00239.21 EMT50022.1 - 6.2e-34 117.2 0.1 1.4e-33 116.1 0.1 1.6 1 0 0 1 1 1 1 Resolvase, N terminal domain Recombinase PF07508.13 EMT50022.1 - 1.7e-31 108.7 4.2 1.7e-31 108.7 4.2 2.4 3 0 0 3 3 3 1 Recombinase Zn_ribbon_recom PF13408.6 EMT50022.1 - 1.9e-11 44.3 3.9 5.1e-11 42.9 3.9 1.8 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Med9 PF07544.13 EMT50022.1 - 0.00062 19.8 1.3 0.0019 18.3 1.3 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF4407 PF14362.6 EMT50022.1 - 0.0075 15.7 1.1 0.012 15.0 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) UPF0172 PF03665.13 EMT50022.1 - 0.03 14.4 0.5 0.094 12.8 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) P3A PF08727.11 EMT50022.1 - 0.047 13.1 0.6 0.16 11.3 0.0 2.3 3 0 0 3 3 3 0 Poliovirus 3A protein like Resolvase PF00239.21 EMT50023.1 - 2.8e-34 118.3 0.0 3.7e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain Recombinase PF07508.13 EMT50023.1 - 6.2e-25 87.6 0.1 1.2e-24 86.7 0.1 1.5 1 0 0 1 1 1 1 Recombinase CRISPR_Cas2 PF09827.9 EMT50024.1 - 0.021 15.0 0.0 0.07 13.3 0.0 1.8 2 0 0 2 2 2 0 CRISPR associated protein Cas2 RusA PF05866.11 EMT50024.1 - 0.063 13.8 0.1 1.2 9.7 0.1 2.7 2 2 0 2 2 2 0 Endodeoxyribonuclease RusA DUF3116 PF11313.8 EMT50025.1 - 0.013 15.3 0.5 3.7 7.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3116) Tox-MPTase5 PF15641.6 EMT50025.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 5 RadC PF04002.15 EMT50026.1 - 3e-18 65.9 0.0 6.2e-18 64.9 0.0 1.5 2 0 0 2 2 2 1 RadC-like JAB domain DUF3014 PF11219.8 EMT50026.1 - 0.022 15.0 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) SopD PF11047.8 EMT50026.1 - 0.037 13.2 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Salmonella outer protein D DUF4769 PF15992.5 EMT50026.1 - 0.074 12.8 0.6 0.14 11.9 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4769) RadC PF04002.15 EMT50027.1 - 2.7e-33 114.5 0.0 3.9e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 RadC-like JAB domain HHH_2 PF12826.7 EMT50027.1 - 0.00018 21.5 0.0 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EMT50027.1 - 0.00065 20.3 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 EMT50027.1 - 0.011 15.6 0.1 0.039 13.8 0.1 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif HhH-GPD PF00730.25 EMT50027.1 - 0.052 14.0 0.0 0.064 13.7 0.0 1.3 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Prok-JAB PF14464.6 EMT50027.1 - 0.06 13.1 0.1 0.089 12.6 0.1 1.4 1 1 0 1 1 1 0 Prokaryotic homologs of the JAB domain DUF3701 PF12482.8 EMT50027.1 - 0.064 13.3 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Phage integrase protein ArdA PF07275.11 EMT50031.1 - 1.6e-33 116.6 3.4 1.9e-33 116.3 3.4 1.0 1 0 0 1 1 1 1 Antirestriction protein (ArdA) HTH_3 PF01381.22 EMT50032.1 - 1e-16 60.7 0.1 1.4e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EMT50032.1 - 6.8e-12 45.2 0.3 1.2e-11 44.5 0.1 1.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 EMT50032.1 - 2.1e-11 44.0 0.0 3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 EMT50032.1 - 2e-07 30.8 0.1 5.6e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 EMT50032.1 - 6.5e-07 29.7 0.0 2.9e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EMT50032.1 - 0.0014 18.5 0.0 0.004 17.0 0.0 1.8 1 1 1 2 2 2 1 Helix-turn-helix domain Flagellin_N PF00669.20 EMT50033.1 - 2e-36 125.2 13.2 2e-36 125.2 13.2 2.2 2 1 0 2 2 2 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 EMT50033.1 - 1.8e-21 76.2 2.9 1.8e-21 76.2 2.9 3.0 4 0 0 4 4 4 1 Bacterial flagellin C-terminal helical region UPF0547 PF10571.9 EMT50034.1 - 1.6e-07 31.3 4.3 1.6e-07 31.3 4.3 1.7 2 0 0 2 2 1 1 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 EMT50034.1 - 2.3e-06 26.8 0.7 5.5e-06 25.6 0.7 1.7 1 0 0 1 1 1 1 zinc-ribbon domain DUF4064 PF13273.6 EMT50034.1 - 0.0022 18.3 0.5 0.0041 17.4 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) CD20 PF04103.15 EMT50034.1 - 0.0025 17.9 2.5 0.0045 17.1 2.5 1.6 1 1 0 1 1 1 1 CD20-like family zinc_ribbon_2 PF13240.6 EMT50034.1 - 0.0032 17.1 2.0 0.0063 16.2 2.0 1.5 1 0 0 1 1 1 1 zinc-ribbon domain TctB PF07331.11 EMT50034.1 - 0.0063 16.8 0.1 0.0098 16.2 0.1 1.4 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family Phage_holin_3_6 PF07332.11 EMT50034.1 - 0.0078 16.2 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III YiaAB PF05360.14 EMT50034.1 - 0.011 16.0 6.3 0.03 14.5 6.2 1.7 1 1 0 1 1 1 0 yiaA/B two helix domain DUF3169 PF11368.8 EMT50034.1 - 0.011 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF2232 PF09991.9 EMT50034.1 - 0.016 14.4 2.8 0.035 13.3 2.8 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) MFS_2 PF13347.6 EMT50034.1 - 0.02 13.4 0.2 0.026 13.1 0.2 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Ly49 PF08391.10 EMT50034.1 - 0.035 14.4 5.3 0.084 13.2 1.5 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF1218 PF06749.12 EMT50034.1 - 0.043 14.3 3.8 0.7 10.5 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) DZR PF12773.7 EMT50034.1 - 0.057 13.5 5.0 0.12 12.5 5.0 1.6 1 1 0 1 1 1 0 Double zinc ribbon DUF1201 PF06716.11 EMT50034.1 - 0.078 13.0 0.7 0.11 12.5 0.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1201) DUF2207 PF09972.9 EMT50034.1 - 0.081 11.7 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FapA PF03961.13 EMT50034.1 - 0.09 11.4 3.3 0.031 12.9 0.4 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A zinc_ribbon_15 PF17032.5 EMT50034.1 - 0.11 13.3 5.4 0.25 12.1 5.4 1.7 1 1 0 1 1 1 0 zinc-ribbon family Prefoldin_2 PF01920.20 EMT50034.1 - 0.17 11.8 9.4 0.28 11.2 0.3 2.8 3 0 0 3 3 3 0 Prefoldin subunit DUF202 PF02656.15 EMT50034.1 - 0.18 12.2 4.0 0.31 11.5 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Saf_2TM PF18303.1 EMT50034.1 - 0.25 10.9 4.4 2 8.0 4.4 2.0 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain OrfB_Zn_ribbon PF07282.11 EMT50034.1 - 0.25 11.3 2.5 0.73 9.8 0.9 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF3021 PF11457.8 EMT50034.1 - 0.29 11.5 4.7 0.45 10.8 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) tRNA-synt_1g PF09334.11 EMT50034.1 - 0.69 8.6 3.8 0.95 8.1 3.8 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) DUF5362 PF17319.2 EMT50034.1 - 1.4 8.8 10.2 0.19 11.6 0.9 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5362) OmpH PF03938.14 EMT50034.1 - 2 8.7 13.6 2.1 8.7 7.1 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spc24 PF08286.11 EMT50034.1 - 2.8 8.2 8.9 5.8 7.2 4.1 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2929 PF11151.8 EMT50034.1 - 3.8 7.9 6.6 56 4.1 6.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2929) DUF4140 PF13600.6 EMT50034.1 - 5.8 7.4 6.6 0.48 10.9 0.3 2.2 3 0 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) FlxA PF14282.6 EMT50034.1 - 6.7 6.8 10.8 1.1 9.3 6.9 1.6 2 0 0 2 2 2 0 FlxA-like protein Tetraspanin PF00335.20 EMT50034.1 - 7.3 6.2 7.3 9 5.9 6.6 1.5 1 1 0 1 1 1 0 Tetraspanin family DHHC PF01529.20 EMT50034.1 - 9.9 6.3 10.3 3.4 7.8 1.2 2.5 2 1 0 2 2 2 0 DHHC palmitoyltransferase QueH PF02677.14 EMT50036.1 - 0.18 11.9 2.1 10 6.2 0.1 2.2 2 0 0 2 2 2 0 Epoxyqueuosine reductase QueH Transposase_mut PF00872.18 EMT50038.1 - 1.8e-27 96.2 0.3 1.9e-27 96.1 0.3 1.0 1 0 0 1 1 1 1 Transposase, Mutator family SRP68 PF16969.5 EMT50038.1 - 0.014 14.4 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 Rep_2 PF01719.17 EMT50038.1 - 0.035 13.9 0.6 0.037 13.8 0.6 1.1 1 0 0 1 1 1 0 Plasmid replication protein TssO PF17561.2 EMT50038.1 - 0.24 11.5 3.0 0.17 12.0 1.7 1.4 2 0 0 2 2 2 0 Type VI secretion system, TssO ATP-synt_ab PF00006.25 EMT50040.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SSF PF00482.23 EMT50041.1 - 1.8e-13 50.6 1.8 1.8e-13 50.6 1.8 2.1 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein F Peptidase_U4 PF03419.13 EMT50041.1 - 0.12 11.6 3.3 0.22 10.8 3.3 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA T2SSF PF00482.23 EMT50042.1 - 8.7e-12 45.1 2.3 8.7e-12 45.1 2.3 3.3 3 2 0 3 3 3 1 Type II secretion system (T2SS), protein F Thr_synth_N PF14821.6 EMT50042.1 - 0.025 14.8 0.2 0.33 11.2 0.0 2.6 2 1 1 3 3 3 0 Threonine synthase N terminus RseC_MucC PF04246.12 EMT50042.1 - 0.19 11.7 0.2 0.19 11.7 0.2 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SirB PF04247.12 EMT50042.1 - 5.9 7.0 10.8 25 5.0 0.3 3.2 3 0 0 3 3 3 0 Invasion gene expression up-regulator, SirB T2SSE PF00437.20 EMT50043.1 - 2.6e-74 249.7 1.2 4e-74 249.1 1.2 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein dsDNA_bind PF01984.20 EMT50043.1 - 0.00052 20.3 5.2 0.0013 19.0 5.2 1.7 1 0 0 1 1 1 1 Double-stranded DNA-binding domain AAA_28 PF13521.6 EMT50043.1 - 0.0016 18.7 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EMT50043.1 - 0.0016 17.9 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 EMT50043.1 - 0.0028 17.0 0.0 0.0061 15.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.27 EMT50043.1 - 0.004 17.7 0.0 0.03 14.8 0.0 2.2 2 1 0 2 2 2 1 ABC transporter ATP_bind_1 PF03029.17 EMT50043.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein IIGP PF05049.13 EMT50043.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 EMT50043.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT50043.1 - 0.02 15.2 0.1 0.075 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EMT50043.1 - 0.045 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 EMT50043.1 - 0.054 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 EMT50043.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EMT50043.1 - 0.056 13.9 0.2 0.056 13.9 0.2 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EMT50043.1 - 0.061 12.9 0.4 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DNA_pol_A_exoN PF18305.1 EMT50043.1 - 0.084 13.2 0.5 0.22 11.9 0.5 1.7 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain AAA_30 PF13604.6 EMT50043.1 - 0.093 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EMT50043.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase Dynamin_N PF00350.23 EMT50043.1 - 0.1 12.6 0.3 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 EMT50043.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMT50043.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 EMT50043.1 - 0.13 12.0 0.8 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain CbiA PF01656.23 EMT50043.1 - 0.19 11.8 0.1 0.44 10.6 0.0 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EMT50044.1 - 1.7e-13 50.8 0.4 1.7e-13 50.8 0.4 1.5 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EMT50044.1 - 1.7e-11 44.2 0.0 8.5e-11 42.0 0.0 2.1 2 2 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EMT50044.1 - 4e-07 29.5 3.4 5.2e-07 29.1 1.0 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase ParA PF10609.9 EMT50044.1 - 7.8e-07 28.8 0.1 1.4e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 EMT50044.1 - 0.00093 18.7 0.3 0.013 15.0 0.3 2.3 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Response_reg PF00072.24 EMT50044.1 - 0.0019 18.3 0.8 0.0083 16.3 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain Snf7 PF03357.21 EMT50044.1 - 0.024 14.3 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 Snf7 Fer4_NifH PF00142.18 EMT50044.1 - 0.037 13.5 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 EMT50044.1 - 0.09 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 EMT50044.1 - 0.11 12.0 2.9 0.25 10.9 1.0 2.2 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 EMT50044.1 - 0.13 11.9 1.7 4.7 6.8 0.3 2.2 1 1 0 2 2 2 0 SRP54-type protein, GTPase domain RcpC PF16976.5 EMT50045.1 - 2.8e-18 66.1 0.1 4.6e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 Flp pilus assembly protein RcpC/CpaB SAF PF08666.12 EMT50045.1 - 5.2e-05 23.8 0.9 0.00011 22.8 0.9 1.6 1 0 0 1 1 1 1 SAF domain RES PF08808.11 EMT50045.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 RES domain p450 PF00067.22 EMT50046.1 - 2.3e-41 142.0 0.0 4.5e-39 134.5 0.0 2.8 1 1 0 1 1 1 1 Cytochrome P450 DinB PF05163.12 EMT50047.1 - 1.6e-35 122.5 1.2 1.9e-35 122.3 1.2 1.0 1 0 0 1 1 1 1 DinB family DinB_2 PF12867.7 EMT50047.1 - 1.5e-09 38.5 0.2 1.8e-09 38.2 0.2 1.1 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 EMT50047.1 - 3.2e-07 30.9 0.1 4.3e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF664) YkyA PF10368.9 EMT50047.1 - 0.088 12.5 0.3 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein VRR_NUC PF08774.11 EMT50047.1 - 0.096 12.8 0.0 0.65 10.1 0.0 2.1 1 1 1 2 2 2 0 VRR-NUC domain DUF5304 PF17230.2 EMT50047.1 - 0.17 12.1 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5304) WYL PF13280.6 EMT50048.1 - 8e-35 120.4 0.1 1.1e-34 120.0 0.1 1.2 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 EMT50048.1 - 2e-12 46.8 0.0 3.7e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 EMT50048.1 - 0.00075 19.2 0.1 0.0021 17.8 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 EMT50048.1 - 0.0011 18.5 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 EMT50048.1 - 0.004 17.1 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix Rrf2 PF02082.20 EMT50048.1 - 0.0088 16.4 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator MarR PF01047.22 EMT50048.1 - 0.011 15.7 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 EMT50048.1 - 0.056 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 EMT50048.1 - 0.1 12.5 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 EMT50048.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_32 PF13565.6 EMT50048.1 - 0.15 12.7 1.1 7 7.3 0.1 2.9 3 1 1 4 4 3 0 Homeodomain-like domain HTH_17 PF12728.7 EMT50048.1 - 0.15 12.2 2.3 0.19 11.9 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain TrmB PF01978.19 EMT50048.1 - 0.15 11.9 0.0 0.43 10.5 0.0 1.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HSDR_N_2 PF13588.6 EMT50049.1 - 0.021 14.8 0.3 0.029 14.4 0.3 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF1640 PF07798.11 EMT50049.1 - 0.038 14.0 0.6 0.063 13.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) SlyX PF04102.12 EMT50050.1 - 1e-06 29.2 4.3 3.8e-05 24.2 2.7 2.3 2 0 0 2 2 2 1 SlyX DUF16 PF01519.16 EMT50050.1 - 6.5e-06 26.6 5.0 7.6e-05 23.1 4.0 2.2 1 1 1 2 2 2 1 Protein of unknown function DUF16 NPV_P10 PF05531.12 EMT50050.1 - 8.7e-06 26.1 0.3 0.0013 19.2 0.0 2.2 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein HrpB7 PF09486.10 EMT50050.1 - 8.7e-05 23.0 2.8 8.7e-05 23.0 2.8 1.5 2 0 0 2 2 1 1 Bacterial type III secretion protein (HrpB7) EzrA PF06160.12 EMT50050.1 - 0.00014 20.3 3.0 0.00017 19.9 3.0 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Jnk-SapK_ap_N PF09744.9 EMT50050.1 - 0.00018 21.7 5.2 0.00022 21.5 5.2 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 XhlA PF10779.9 EMT50050.1 - 0.0002 21.5 7.7 0.035 14.3 0.2 3.0 1 1 2 3 3 3 1 Haemolysin XhlA Fib_alpha PF08702.10 EMT50050.1 - 0.0002 21.6 1.6 0.0006 20.0 0.2 1.9 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family PspA_IM30 PF04012.12 EMT50050.1 - 0.00028 20.5 3.9 0.0014 18.3 3.9 1.8 1 1 0 1 1 1 1 PspA/IM30 family ERM PF00769.19 EMT50050.1 - 0.00039 20.3 4.6 0.00046 20.1 4.6 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.7 EMT50050.1 - 0.00039 20.6 6.6 0.0008 19.6 6.5 1.6 1 1 0 1 1 1 1 Tropomyosin like Trimer_CC PF08954.11 EMT50050.1 - 0.0015 18.1 10.3 0.008 15.7 3.4 2.5 1 1 1 2 2 2 1 Trimerisation motif BLOC1_2 PF10046.9 EMT50050.1 - 0.0018 18.5 1.3 0.0049 17.1 0.3 2.0 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Not3 PF04065.15 EMT50050.1 - 0.0019 17.6 2.6 0.0023 17.4 2.6 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component DASH_Spc19 PF08287.11 EMT50050.1 - 0.0035 17.2 3.6 0.033 14.1 3.6 2.0 1 1 0 1 1 1 1 Spc19 Exonuc_VII_L PF02601.15 EMT50050.1 - 0.0042 16.7 1.6 0.0046 16.6 1.6 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit TMPIT PF07851.13 EMT50050.1 - 0.0043 16.4 1.2 0.0046 16.2 1.2 1.0 1 0 0 1 1 1 1 TMPIT-like protein CENP-F_leu_zip PF10473.9 EMT50050.1 - 0.0045 17.0 7.8 0.0059 16.6 7.8 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLZ PF16526.5 EMT50050.1 - 0.0047 17.3 5.6 0.057 13.8 2.5 2.8 1 1 2 3 3 3 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADIP PF11559.8 EMT50050.1 - 0.0053 16.9 2.9 0.0075 16.4 1.8 1.6 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding HAP1_N PF04849.13 EMT50050.1 - 0.0073 15.5 6.8 0.0081 15.4 6.8 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Phage_GP20 PF06810.11 EMT50050.1 - 0.0078 16.0 1.4 0.0091 15.8 1.4 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 FPP PF05911.11 EMT50050.1 - 0.0093 14.2 3.4 0.011 14.0 3.4 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil HalX PF08663.10 EMT50050.1 - 0.01 16.1 8.3 2.1 8.7 8.4 2.5 1 1 0 1 1 1 0 HalX domain DUF3552 PF12072.8 EMT50050.1 - 0.011 15.2 9.5 0.0096 15.4 8.5 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) CENP-Q PF13094.6 EMT50050.1 - 0.012 15.8 2.4 0.014 15.6 2.4 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.12 EMT50050.1 - 0.013 15.5 3.3 0.18 11.8 3.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EMT50050.1 - 0.014 15.8 3.8 0.2 12.1 0.5 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 EMT50050.1 - 0.014 15.4 2.4 0.036 14.1 1.4 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.8 EMT50050.1 - 0.015 14.6 2.3 0.018 14.3 1.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UPF0184 PF03670.13 EMT50050.1 - 0.02 15.3 2.7 1.3 9.5 0.3 2.6 1 1 2 3 3 2 0 Uncharacterised protein family (UPF0184) DUF2203 PF09969.9 EMT50050.1 - 0.022 15.5 3.4 0.032 15.0 1.5 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Snapin_Pallidin PF14712.6 EMT50050.1 - 0.023 15.1 4.2 1.7 9.1 4.2 2.3 1 1 0 1 1 1 0 Snapin/Pallidin Phage_GPO PF05929.11 EMT50050.1 - 0.023 14.3 0.4 0.028 14.1 0.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Lebercilin PF15619.6 EMT50050.1 - 0.026 14.2 8.1 0.067 12.9 4.3 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Cep57_CLD PF14073.6 EMT50050.1 - 0.026 14.5 3.5 0.026 14.5 3.5 1.5 2 0 0 2 2 1 0 Centrosome localisation domain of Cep57 Spectrin PF00435.21 EMT50050.1 - 0.029 14.9 3.2 0.43 11.1 3.1 2.4 1 1 0 1 1 1 0 Spectrin repeat Occludin_ELL PF07303.13 EMT50050.1 - 0.029 15.1 2.5 0.83 10.4 0.9 2.1 1 1 1 2 2 2 0 Occludin homology domain Fez1 PF06818.15 EMT50050.1 - 0.029 14.8 4.4 0.04 14.4 4.4 1.3 1 1 0 1 1 1 0 Fez1 DUF2730 PF10805.8 EMT50050.1 - 0.03 14.4 2.6 0.73 10.0 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) ABC_tran_CTD PF16326.5 EMT50050.1 - 0.031 14.5 3.5 0.53 10.6 2.6 2.7 1 1 2 3 3 3 0 ABC transporter C-terminal domain Spc29 PF17082.5 EMT50050.1 - 0.032 14.1 3.9 0.067 13.0 3.7 1.6 1 1 0 1 1 1 0 Spindle Pole Component 29 ZapB PF06005.12 EMT50050.1 - 0.035 14.5 5.1 0.58 10.6 4.9 3.0 1 1 0 1 1 1 0 Cell division protein ZapB DUF4164 PF13747.6 EMT50050.1 - 0.036 14.3 6.4 0.1 12.9 6.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Vps5 PF09325.10 EMT50050.1 - 0.037 13.6 6.9 0.061 12.9 6.5 1.6 1 1 0 1 1 1 0 Vps5 C terminal like HSBP1 PF06825.12 EMT50050.1 - 0.038 13.8 6.7 1.4 8.8 0.3 3.4 2 1 1 3 3 3 0 Heat shock factor binding protein 1 DUF1241 PF06840.11 EMT50050.1 - 0.04 13.6 3.2 0.077 12.6 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1241) Troponin PF00992.20 EMT50050.1 - 0.045 14.0 8.0 0.026 14.8 5.9 1.7 1 1 0 1 1 1 0 Troponin Tropomyosin PF00261.20 EMT50050.1 - 0.046 13.1 9.2 0.03 13.7 6.0 1.9 1 1 1 2 2 2 0 Tropomyosin DASH_Spc34 PF08657.10 EMT50050.1 - 0.051 13.4 3.0 0.093 12.5 3.0 1.5 1 1 0 1 1 1 0 DASH complex subunit Spc34 Osmo_CC PF08946.10 EMT50050.1 - 0.053 13.8 5.6 1.1 9.6 0.7 3.3 1 1 2 3 3 3 0 Osmosensory transporter coiled coil YkyA PF10368.9 EMT50050.1 - 0.054 13.2 3.6 0.092 12.4 3.6 1.5 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Dynactin_p22 PF07426.11 EMT50050.1 - 0.056 13.3 3.5 1.8 8.4 0.6 2.6 1 1 2 3 3 3 0 Dynactin subunit p22 GAS PF13851.6 EMT50050.1 - 0.057 12.8 7.5 0.039 13.3 4.8 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 EMT50050.1 - 0.064 13.3 3.2 0.23 11.5 2.0 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein OmpH PF03938.14 EMT50050.1 - 0.067 13.5 1.9 0.078 13.3 1.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 EMT50050.1 - 0.07 13.1 2.0 0.18 11.8 1.9 1.7 1 1 0 1 1 1 0 Laminin Domain II DivIC PF04977.15 EMT50050.1 - 0.082 12.7 7.4 0.49 10.2 4.0 2.9 1 1 2 3 3 3 0 Septum formation initiator bZIP_1 PF00170.21 EMT50050.1 - 0.094 12.8 4.4 2.9 8.1 0.2 2.7 1 1 1 2 2 2 0 bZIP transcription factor TelA PF05816.11 EMT50050.1 - 0.11 11.6 3.9 0.57 9.2 3.9 1.9 1 1 0 1 1 1 0 Toxic anion resistance protein (TelA) Spc7 PF08317.11 EMT50050.1 - 0.11 11.4 4.4 0.13 11.2 4.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 EMT50050.1 - 0.13 12.6 0.1 0.59 10.4 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2802 PF10975.8 EMT50050.1 - 0.13 12.4 2.2 4.5 7.5 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) Vac_Fusion PF02346.16 EMT50050.1 - 0.17 11.5 4.9 0.34 10.6 0.4 2.5 2 1 1 3 3 2 0 Chordopoxvirus multifunctional envelope protein A27 TraF_2 PF13729.6 EMT50050.1 - 0.21 10.9 1.4 0.45 9.8 1.4 1.6 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein YabA PF06156.13 EMT50050.1 - 0.23 12.1 3.0 0.91 10.2 3.0 1.9 1 1 1 2 2 2 0 Initiation control protein YabA YvrJ PF12841.7 EMT50050.1 - 0.27 10.8 0.8 18 4.9 0.0 3.0 1 1 1 3 3 2 0 YvrJ protein family Fzo_mitofusin PF04799.13 EMT50050.1 - 0.36 10.4 2.4 1 8.9 2.3 1.8 1 1 0 1 1 1 0 fzo-like conserved region TMF_TATA_bd PF12325.8 EMT50050.1 - 0.4 10.9 7.9 0.48 10.7 5.7 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 EMT50050.1 - 0.52 10.6 5.3 3.1 8.1 0.9 2.9 2 1 1 3 3 2 0 Homeobox associated leucine zipper DUF5446 PF17522.2 EMT50050.1 - 0.54 10.5 5.7 2.4 8.4 3.3 2.6 2 1 0 2 2 1 0 Family of unknown function (DUF5446) bZIP_2 PF07716.15 EMT50050.1 - 0.75 9.9 7.9 5.8 7.1 1.1 2.7 2 1 1 3 3 2 0 Basic region leucine zipper UPF0242 PF06785.11 EMT50050.1 - 0.75 9.9 5.2 1.4 9.0 5.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BMFP PF04380.13 EMT50050.1 - 1.8 9.1 10.5 4.9 7.7 4.3 2.7 2 1 1 3 3 2 0 Membrane fusogenic activity CorA PF01544.18 EMT50050.1 - 4.5 6.5 7.1 15 4.8 0.3 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein MtrG PF04210.13 EMT50050.1 - 4.8 7.1 6.8 6.8 6.6 1.0 3.0 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Peripla_BP_2 PF01497.18 EMT50051.1 - 1.2e-35 123.2 0.6 1.5e-35 122.9 0.6 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ABC_tran PF00005.27 EMT50052.1 - 2.4e-32 112.3 0.0 3.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT50052.1 - 8.3e-09 35.7 0.1 0.00016 21.6 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT50052.1 - 2e-08 34.0 1.3 1e-05 25.1 1.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT50052.1 - 8.9e-08 32.2 0.2 6.4e-07 29.4 0.1 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EMT50052.1 - 0.00011 21.8 0.1 0.00021 20.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT50052.1 - 0.00049 20.7 1.2 0.0011 19.5 1.2 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT50052.1 - 0.00065 19.6 0.1 0.0013 18.7 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase ATP_bind_1 PF03029.17 EMT50052.1 - 0.0012 18.6 0.1 0.78 9.5 0.1 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 EMT50052.1 - 0.0014 18.7 1.4 1.3 9.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EMT50052.1 - 0.0034 17.6 0.1 0.041 14.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMT50052.1 - 0.0039 16.8 0.2 0.047 13.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMT50052.1 - 0.0095 15.7 0.0 0.019 14.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMT50052.1 - 0.018 15.4 0.0 0.037 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 EMT50052.1 - 0.019 13.8 3.4 0.24 10.2 0.1 3.2 2 2 1 3 3 3 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 EMT50052.1 - 0.02 15.1 0.0 1.2 9.4 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EMT50052.1 - 0.052 13.3 0.7 0.32 10.7 0.3 2.1 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EMT50052.1 - 0.06 13.6 0.4 0.21 11.9 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EMT50052.1 - 0.072 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EMT50052.1 - 0.087 12.3 0.3 0.49 9.8 0.0 2.2 2 1 0 2 2 2 0 PhoH-like protein Corona_M PF01635.18 EMT50052.1 - 0.094 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein FecCD PF01032.18 EMT50053.1 - 4.4e-53 180.3 30.7 5.7e-53 179.9 30.7 1.2 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 EMT50053.1 - 0.0017 17.9 20.2 0.0017 17.9 20.2 1.6 2 0 0 2 2 2 1 ABC 3 transport family DUF4024 PF13216.6 EMT50053.1 - 0.03 14.2 2.2 0.093 12.7 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4024) FMP23 PF17315.2 EMT50053.1 - 0.16 12.1 0.8 0.31 11.2 0.3 1.7 2 0 0 2 2 2 0 Found in mitochondrial proteome DUF1689 PF07954.11 EMT50053.1 - 0.31 11.4 10.2 1.2 9.5 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1689) FecCD PF01032.18 EMT50054.1 - 6e-66 222.6 27.9 6.8e-66 222.4 27.9 1.0 1 0 0 1 1 1 1 FecCD transport family Phage_holin_5_1 PF06946.11 EMT50054.1 - 0.26 11.7 4.8 0.3 11.5 0.5 2.8 2 1 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 DUF1449 PF07290.11 EMT50054.1 - 3.2 7.3 12.9 0.21 11.2 1.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1449) FMN_red PF03358.15 EMT50055.1 - 6.3e-28 97.5 0.0 8.2e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EMT50055.1 - 5.8e-08 32.7 0.0 7.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold MFS_1 PF07690.16 EMT50056.1 - 2.4e-06 26.7 1.3 2.6e-06 26.6 1.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 EMT50057.1 - 0.00059 18.4 0.2 0.00062 18.3 0.2 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 EMT50057.1 - 0.053 12.4 0.8 0.051 12.5 0.8 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Fe-S_biosyn PF01521.20 EMT50058.1 - 1.4e-05 25.2 0.0 1.7e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis EamA PF00892.20 EMT50059.1 - 8.1e-43 145.9 38.5 5.9e-23 81.5 16.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EMT50059.1 - 3e-10 39.9 21.4 3.6e-10 39.7 21.4 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 EMT50059.1 - 0.00061 18.8 16.7 0.021 13.8 6.1 2.4 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 EMT50059.1 - 4.4 7.4 10.9 0.33 11.0 3.3 2.6 1 1 1 3 3 3 0 Putative transmembrane family 234 Aminotran_1_2 PF00155.21 EMT50060.1 - 1.9e-23 83.2 0.0 2.6e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EMT50060.1 - 2.3e-13 49.6 0.0 2.6e-12 46.2 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 EMT50060.1 - 1e-05 24.6 0.0 1.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase HTH_36 PF13730.6 EMT50060.1 - 2.3e-05 24.2 0.0 9.8e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 EMT50060.1 - 4.3e-05 23.4 0.2 0.0015 18.4 0.0 3.2 3 0 0 3 3 3 1 HTH domain HTH_Crp_2 PF13545.6 EMT50060.1 - 0.00071 19.5 0.0 0.0074 16.2 0.0 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_50 PF18024.1 EMT50060.1 - 0.0021 17.6 0.0 0.0072 15.9 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_41 PF14502.6 EMT50060.1 - 0.0069 16.0 0.0 0.025 14.3 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 EMT50060.1 - 0.036 13.6 0.2 0.17 11.5 0.0 2.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 EMT50060.1 - 0.13 12.1 0.5 0.52 10.2 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Oxidored_FMN PF00724.20 EMT50061.1 - 1.3e-88 297.6 0.0 1.5e-88 297.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DHO_dh PF01180.21 EMT50061.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF1877 PF08974.10 EMT50061.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) GGDEF_2 PF17853.1 EMT50061.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 GGDEF-like domain Bac_luciferase PF00296.20 EMT50062.1 - 5.2e-40 137.8 0.3 2.5e-39 135.5 0.3 1.8 1 1 0 1 1 1 1 Luciferase-like monooxygenase HTH_20 PF12840.7 EMT50063.1 - 1.3e-11 44.4 0.0 1.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EMT50063.1 - 6.6e-08 32.3 0.2 2.2e-05 24.2 0.3 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 EMT50063.1 - 1.1e-06 28.3 0.4 4e-06 26.5 0.1 2.1 2 1 0 2 2 2 1 IclR helix-turn-helix domain MarR PF01047.22 EMT50063.1 - 0.00069 19.5 0.1 0.014 15.3 0.0 2.4 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 EMT50063.1 - 0.00095 18.7 0.2 0.0045 16.5 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_46 PF15977.5 EMT50063.1 - 0.0019 18.2 0.0 0.004 17.1 0.0 1.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA binding HTH_40 PF14493.6 EMT50063.1 - 0.0039 17.6 0.0 0.008 16.6 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 EMT50063.1 - 0.0047 16.8 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 EMT50063.1 - 0.0085 16.1 0.0 0.015 15.3 0.0 1.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 EMT50063.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.7 1 1 0 1 1 1 0 Homeodomain-like domain HTH_36 PF13730.6 EMT50063.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 EMT50063.1 - 0.025 14.5 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 EMT50063.1 - 0.025 14.8 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 EMT50063.1 - 0.028 14.8 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator Phage_int_SAM_1 PF02899.17 EMT50063.1 - 0.029 14.7 0.0 3.4 8.0 0.1 2.3 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain FUR PF01475.19 EMT50063.1 - 0.04 14.0 0.0 0.099 12.8 0.0 1.5 1 1 0 1 1 1 0 Ferric uptake regulator family LacI PF00356.21 EMT50063.1 - 0.23 11.3 0.0 0.64 9.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family ADH_zinc_N PF00107.26 EMT50064.1 - 8.2e-27 93.7 0.2 1.4e-26 93.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMT50064.1 - 2.5e-23 83.6 0.1 7.4e-23 82.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMT50064.1 - 9.1e-12 44.8 0.1 1e-10 41.5 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Corona_7 PF02398.16 EMT50065.1 - 0.044 14.3 0.4 0.05 14.2 0.4 1.1 1 0 0 1 1 1 0 Coronavirus protein 7 ABC_membrane PF00664.23 EMT50066.1 - 1.2e-56 192.4 8.4 1.5e-56 192.1 8.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMT50066.1 - 1.5e-36 125.9 0.0 4.1e-36 124.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EMT50066.1 - 5.6e-10 39.0 0.0 6.7e-09 35.5 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMT50066.1 - 0.00013 22.4 0.0 0.00039 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain ABC_membrane_3 PF13748.6 EMT50066.1 - 0.00075 18.8 5.6 0.0058 15.9 0.7 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_22 PF13401.6 EMT50066.1 - 0.0017 18.7 0.1 0.014 15.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EMT50066.1 - 0.0036 17.7 0.1 0.059 13.8 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EMT50066.1 - 0.0089 16.0 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase DEAD PF00270.29 EMT50066.1 - 0.01 15.6 0.0 0.03 14.1 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_24 PF13479.6 EMT50066.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EMT50066.1 - 0.032 14.0 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase Claudin_2 PF13903.6 EMT50066.1 - 0.051 13.3 0.2 0.051 13.3 0.2 1.7 2 0 0 2 2 1 0 PMP-22/EMP/MP20/Claudin tight junction AAA_30 PF13604.6 EMT50066.1 - 0.054 13.2 0.1 0.21 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EMT50066.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 EMT50066.1 - 0.059 13.1 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EMT50066.1 - 0.072 13.6 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMT50066.1 - 0.082 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EMT50066.1 - 0.12 11.9 0.0 0.37 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMT50066.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region APS_kinase PF01583.20 EMT50066.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Acetyltransf_7 PF13508.7 EMT50067.1 - 1.3e-09 38.3 0.0 2.1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT50067.1 - 1.2e-06 28.5 0.0 2.3e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT50067.1 - 1.7e-05 25.0 0.0 3.6e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 EMT50067.1 - 0.0029 17.1 0.0 0.038 13.5 0.0 2.1 1 1 1 2 2 2 1 Putative acetyl-transferase TFIIE_alpha PF02002.17 EMT50067.1 - 0.073 12.9 3.4 0.1 12.5 0.3 2.2 1 1 1 2 2 2 0 TFIIE alpha subunit FR47 PF08445.10 EMT50067.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein AA_permease PF00324.21 EMT50068.1 - 1.4e-92 310.8 50.3 1.7e-92 310.5 50.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMT50068.1 - 3.7e-42 144.7 53.0 4.4e-42 144.4 53.0 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 EMT50068.1 - 0.0032 18.2 0.3 0.0032 18.2 0.3 5.0 1 1 2 4 4 4 1 PrgI family protein 2TM PF13239.6 EMT50068.1 - 0.052 13.9 0.4 0.052 13.9 0.4 4.8 4 1 1 5 5 5 0 2TM domain Tautomerase PF01361.21 EMT50069.1 - 9.3e-18 63.9 1.2 1e-17 63.8 1.2 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.6 EMT50069.1 - 2.2e-09 37.3 0.0 2.5e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Peptidase_M20 PF01546.28 EMT50070.1 - 1.1e-31 110.2 0.6 1.5e-31 109.8 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT50070.1 - 3e-11 43.2 0.1 1.7e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain OSR1_C PF12202.8 EMT50070.1 - 0.0058 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Peptidase_M28 PF04389.17 EMT50070.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M28 DinB PF05163.12 EMT50071.1 - 1.2e-36 126.2 1.4 1.3e-36 126.1 1.4 1.0 1 0 0 1 1 1 1 DinB family DinB_2 PF12867.7 EMT50071.1 - 1.1e-06 29.2 0.0 1.3e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 EMT50071.1 - 0.00025 21.5 0.0 0.00032 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF664) MFS_1 PF07690.16 EMT50072.1 - 3e-43 148.1 91.9 8.8e-37 126.8 51.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMT50072.1 - 0.074 11.6 42.2 0.025 13.2 22.6 2.5 1 1 1 2 2 2 0 MFS/sugar transport protein EamA PF00892.20 EMT50073.1 - 3.3e-33 114.8 40.9 5.2e-17 62.3 12.5 2.0 2 0 0 2 2 2 2 EamA-like transporter family Aminotran_1_2 PF00155.21 EMT50074.1 - 2.3e-24 86.3 0.0 3.3e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EMT50074.1 - 7.1e-14 51.2 0.0 1.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 EMT50074.1 - 1.5e-05 24.0 0.0 4.2e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase HTH_36 PF13730.6 EMT50074.1 - 0.0024 17.8 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 EMT50074.1 - 0.0099 15.8 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 HTH domain GNAT_acetyltran PF12746.7 EMT50075.1 - 1.7e-16 60.6 0.0 2.8e-16 59.8 0.0 1.4 1 1 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_3 PF13302.7 EMT50075.1 - 5.3e-05 23.9 0.1 0.00011 22.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT50075.1 - 0.021 15.0 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TPR_5 PF12688.7 EMT50075.1 - 0.077 13.2 0.1 0.69 10.2 0.0 2.1 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_8 PF13181.6 EMT50075.1 - 0.27 11.6 2.5 0.53 10.6 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMT50075.1 - 0.46 11.2 1.9 18 6.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMT50075.1 - 1.4 9.2 8.8 0.82 9.9 1.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C39_2 PF13529.6 EMT50076.1 - 4e-08 33.9 0.0 5.2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 EMT50076.1 - 0.0017 18.3 0.0 0.0028 17.7 0.0 1.5 1 1 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Guanylate_cyc_2 PF09778.9 EMT50076.1 - 0.0092 15.4 0.1 1.1 8.6 0.1 2.1 2 0 0 2 2 2 2 Guanylylate cyclase Acetyltransf_1 PF00583.25 EMT50077.1 - 3.8e-19 69.0 0.1 5.7e-19 68.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT50077.1 - 1.8e-13 50.7 0.0 3.1e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT50077.1 - 4.3e-12 46.1 0.0 5.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT50077.1 - 3.6e-05 23.9 0.1 4.9e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT50077.1 - 0.012 15.7 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EMT50077.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein PanZ PF12568.8 EMT50077.1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_8 PF13523.6 EMT50077.1 - 0.085 12.5 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain UbiA PF01040.18 EMT50079.1 - 8.2e-59 198.9 16.0 1.2e-58 198.4 16.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3040 PF11239.8 EMT50079.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Popeye PF04831.13 EMT50079.1 - 1.5 9.0 6.4 4.5 7.4 6.4 1.8 1 0 0 1 1 1 0 Popeye protein conserved region TetR_N PF00440.23 EMT50080.1 - 7.6e-16 57.6 2.1 1.5e-15 56.7 2.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 EMT50080.1 - 0.00052 20.2 0.9 0.00091 19.4 0.0 1.8 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal HAD_2 PF13419.6 EMT50080.1 - 0.049 13.7 1.1 0.51 10.4 0.1 2.1 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Hemerythrin PF01814.23 EMT50080.1 - 0.062 13.9 1.8 0.12 13.0 1.6 1.7 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain HAD_2 PF13419.6 EMT50081.1 - 2.5e-14 53.8 0.0 3.1e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMT50081.1 - 1.9e-10 40.7 0.2 4.2e-10 39.5 0.2 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EMT50081.1 - 8.3e-06 26.2 0.0 1.3e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3802 PF12290.8 EMT50081.1 - 0.0088 16.5 0.0 0.013 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3802) HTH_19 PF12844.7 EMT50081.1 - 0.043 13.8 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Metallophos_2 PF12850.7 EMT50082.1 - 6.9e-26 91.4 0.0 9.3e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EMT50082.1 - 7.8e-11 42.9 0.1 4.8e-10 40.3 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 EMT50082.1 - 7.8e-05 22.1 0.1 0.0082 15.5 0.0 2.4 2 0 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily PknH_C PF14032.6 EMT50082.1 - 0.11 12.3 0.2 0.17 11.8 0.2 1.2 1 0 0 1 1 1 0 PknH-like extracellular domain HTH_29 PF13551.6 EMT50083.1 - 0.00016 21.6 0.1 0.035 14.1 0.5 2.4 2 0 0 2 2 2 2 Winged helix-turn helix HTH_28 PF13518.6 EMT50083.1 - 0.0027 17.8 0.1 1.3 9.2 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EMT50083.1 - 0.0039 17.5 1.9 0.064 13.6 1.9 2.6 1 1 0 1 1 1 1 Transposase HTH_32 PF13565.6 EMT50083.1 - 0.011 16.3 0.5 0.019 15.6 0.5 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_23 PF13384.6 EMT50083.1 - 0.017 14.9 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain YaaC PF14175.6 EMT50084.1 - 4.9e-80 269.2 0.1 5.5e-80 269.0 0.1 1.0 1 0 0 1 1 1 1 YaaC-like Protein Mgr1 PF08602.10 EMT50084.1 - 0.072 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit IMPDH PF00478.25 EMT50085.1 - 7e-167 554.7 4.0 8.2e-167 554.5 4.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EMT50085.1 - 2.3e-17 63.2 0.2 2.7e-07 30.9 0.0 2.8 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 EMT50085.1 - 1.6e-10 40.9 11.3 3.2e-05 23.5 3.3 3.0 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 EMT50085.1 - 4.6e-05 23.0 1.7 0.00076 19.0 1.7 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 EMT50085.1 - 9.6e-05 21.7 7.2 0.0036 16.6 0.8 2.6 2 1 1 3 3 3 2 Dihydroorotate dehydrogenase Aldolase PF01081.19 EMT50085.1 - 0.00061 19.3 1.3 0.0016 17.9 1.1 1.8 1 1 0 1 1 1 1 KDPG and KHG aldolase FMN_dh PF01070.18 EMT50085.1 - 0.001 18.2 11.9 0.003 16.6 9.0 2.8 3 1 0 3 3 3 1 FMN-dependent dehydrogenase QRPTase_C PF01729.19 EMT50085.1 - 0.0067 16.2 0.1 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Flavodoxin_4 PF12682.7 EMT50085.1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin TMP-TENI PF02581.17 EMT50085.1 - 0.015 14.7 3.3 0.46 9.8 2.4 2.4 1 1 1 2 2 2 0 Thiamine monophosphate synthase PEP_mutase PF13714.6 EMT50085.1 - 0.03 13.8 1.2 0.073 12.5 0.4 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase ThiG PF05690.14 EMT50085.1 - 0.04 13.2 0.5 0.04 13.2 0.5 2.4 3 1 0 4 4 4 0 Thiazole biosynthesis protein ThiG Dus PF01207.17 EMT50085.1 - 0.065 12.3 0.2 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 EMT50085.1 - 0.16 11.4 2.8 1 8.7 0.0 3.0 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator Peptidase_S11 PF00768.20 EMT50086.1 - 1.1e-84 283.7 0.1 1.5e-84 283.2 0.1 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 EMT50086.1 - 1.9e-14 53.7 0.0 4.7e-14 52.5 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase enzyme family PBP5_C PF07943.13 EMT50086.1 - 2.6e-10 40.4 2.7 6e-10 39.2 2.7 1.6 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase PF00144.24 EMT50086.1 - 0.00079 18.8 0.0 0.002 17.4 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S13 PF02113.15 EMT50086.1 - 0.016 14.0 0.1 0.034 12.9 0.1 1.5 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family SOR_SNZ PF01680.17 EMT50087.1 - 1.9e-107 357.7 5.4 2.4e-107 357.4 5.4 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EMT50087.1 - 3.3e-10 39.7 4.0 9.1e-08 31.7 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EMT50087.1 - 4.5e-05 22.7 0.1 0.026 13.6 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 EMT50087.1 - 0.00014 21.4 3.3 0.0065 15.9 0.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase NanE PF04131.14 EMT50087.1 - 0.00019 20.7 0.3 0.022 13.9 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 EMT50087.1 - 0.0011 18.5 0.5 0.028 13.9 0.0 2.4 2 0 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 EMT50087.1 - 0.0017 17.5 0.0 0.051 12.7 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase IMPDH PF00478.25 EMT50087.1 - 0.018 14.0 0.3 0.051 12.6 0.0 1.5 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain OMPdecase PF00215.24 EMT50087.1 - 0.019 14.6 0.0 1.6 8.3 0.0 2.4 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TetR_C_27 PF17935.1 EMT50087.1 - 0.025 14.6 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Milton PF12448.8 EMT50087.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 Kinesin associated protein SNO PF01174.19 EMT50088.1 - 5.1e-67 225.4 0.0 5.7e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EMT50088.1 - 2.2e-09 37.2 0.0 2.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 EMT50088.1 - 1.2e-07 31.6 0.0 1.7e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 EMT50088.1 - 1.5e-06 28.1 0.1 2.5e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EMT50088.1 - 3.8e-06 26.8 0.3 1.4e-05 25.0 0.3 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EMT50088.1 - 0.05 13.3 1.0 1.9 8.2 1.0 2.7 1 1 0 1 1 1 0 Peptidase C26 tRNA-synt_2b PF00587.25 EMT50089.1 - 3.8e-36 124.7 0.0 6.2e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EMT50089.1 - 2.7e-32 111.2 10.1 5.5e-32 110.2 10.1 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF4795 PF16043.5 EMT50089.1 - 0.00063 19.4 0.3 0.0012 18.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DUF5082 PF16888.5 EMT50089.1 - 0.0027 18.0 0.9 0.0059 16.9 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) UPF0242 PF06785.11 EMT50089.1 - 0.096 12.8 4.0 0.18 11.9 4.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 EMT50089.1 - 0.099 12.0 2.5 0.16 11.3 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HMMR_N PF15905.5 EMT50089.1 - 0.11 12.0 7.1 0.16 11.4 7.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DegS PF05384.11 EMT50089.1 - 0.26 10.7 8.0 0.38 10.2 6.9 1.8 2 0 0 2 2 2 0 Sensor protein DegS PCRF PF03462.18 EMT50089.1 - 0.38 10.6 4.1 0.36 10.7 2.3 1.8 2 0 0 2 2 2 0 PCRF domain FapA PF03961.13 EMT50089.1 - 0.55 8.8 5.4 0.92 8.0 5.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ax_dynein_light PF10211.9 EMT50089.1 - 0.58 10.1 7.2 0.92 9.4 7.2 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain DUF3450 PF11932.8 EMT50089.1 - 0.74 9.1 6.1 1.3 8.3 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 EMT50089.1 - 0.77 8.6 6.8 1.4 7.7 6.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 EMT50089.1 - 0.84 9.7 4.7 1.6 8.8 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 EMT50089.1 - 0.86 8.4 9.8 0.066 12.1 4.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) TMPIT PF07851.13 EMT50089.1 - 0.88 8.7 2.6 1.4 8.1 2.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cauli_AT PF03233.13 EMT50089.1 - 1 9.3 3.9 2 8.3 3.9 1.4 1 0 0 1 1 1 0 Aphid transmission protein DUF1465 PF07323.12 EMT50089.1 - 1.1 9.1 4.3 2.3 8.1 2.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) GAS PF13851.6 EMT50089.1 - 1.2 8.4 11.9 0.56 9.5 8.8 1.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 EMT50089.1 - 1.9 9.0 6.2 2.5 8.6 3.0 2.5 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 EMT50089.1 - 2.2 8.1 8.0 0.29 10.9 3.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Sec34 PF04136.15 EMT50089.1 - 2.3 8.1 5.3 5.6 6.8 0.5 2.6 2 1 1 3 3 3 0 Sec34-like family BLOC1_2 PF10046.9 EMT50089.1 - 9.3 6.6 8.6 6 7.2 5.2 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Malate_synthase PF01274.22 EMT50090.1 - 3.1e-211 702.2 0.0 3.5e-211 702.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 EMT50090.1 - 0.12 11.5 0.0 0.46 9.6 0.0 1.8 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family YdaS_antitoxin PF15943.5 EMT50090.1 - 0.21 11.5 1.0 3.2 7.7 0.3 2.6 2 1 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT ICL PF00463.21 EMT50091.1 - 7.7e-108 361.3 0.9 2.6e-56 191.2 0.0 2.1 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 EMT50091.1 - 6.7e-17 61.7 0.0 1.7e-16 60.4 0.0 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF3338 PF11819.8 EMT50091.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) ADH_zinc_N PF00107.26 EMT50092.1 - 1.1e-13 51.3 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMT50092.1 - 2.7e-13 51.1 0.0 5.2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMT50092.1 - 1.5e-07 31.3 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peptidase_S8 PF00082.22 EMT50093.1 - 5.6e-45 153.9 3.6 5.6e-45 153.9 3.6 1.9 2 0 0 2 2 2 1 Subtilase family PPC PF04151.15 EMT50093.1 - 1.6e-05 25.9 1.2 1.6e-05 25.9 1.2 3.4 2 1 0 2 2 2 1 Bacterial pre-peptidase C-terminal domain Flagellin_D3 PF08884.11 EMT50093.1 - 0.15 12.4 6.7 0.16 12.4 0.3 3.2 3 0 0 3 3 3 0 Flagellin D3 domain CBM_35 PF16990.5 EMT50093.1 - 2.5 8.4 6.6 0.22 11.8 0.7 2.2 3 0 0 3 3 3 0 Carbohydrate binding module (family 35) Tox-ART-HYD1 PF15633.6 EMT50094.1 - 0.2 12.4 1.8 1.1 10.0 0.1 2.3 2 1 1 3 3 3 0 HYD1 signature containing ADP-ribosyltransferase Sigma_reg_N PF13800.6 EMT50094.1 - 0.43 10.9 5.6 0.84 10.0 5.6 1.5 1 1 0 1 1 1 0 Sigma factor regulator N-terminal Cu_amine_oxidN1 PF07833.11 EMT50095.1 - 1.5e-18 67.1 0.1 3.5e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase N-terminal domain DUF4901 PF16244.5 EMT50095.1 - 0.0053 16.2 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4901) SeleniumBinding PF11524.8 EMT50096.1 - 8.9e-06 26.1 0.0 9.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Selenium binding protein YbjQ_1 PF01906.17 EMT50096.1 - 0.017 15.8 0.1 0.043 14.5 0.0 1.7 1 1 0 1 1 1 0 Putative heavy-metal-binding Phage_holin_4_1 PF05105.12 EMT50097.1 - 2.4e-10 40.5 0.1 3e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Bacteriophage holin family Glyco_hydro_56 PF01630.18 EMT50097.1 - 0.2 10.6 0.9 0.24 10.4 0.9 1.1 1 0 0 1 1 1 0 Hyaluronidase Amidase_3 PF01520.18 EMT50098.1 - 1.3e-46 158.9 0.0 1.7e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Cu_amine_oxidN1 PF07833.11 EMT50098.1 - 2e-11 44.2 0.0 4.3e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Copper amine oxidase N-terminal domain ATP_transf PF09830.9 EMT50098.1 - 0.1 12.7 0.1 7.9 6.7 0.0 2.7 3 0 0 3 3 3 0 ATP adenylyltransferase Sigma70_r2 PF04542.14 EMT50099.1 - 1e-11 44.4 0.6 2e-11 43.5 0.6 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT50099.1 - 4e-11 42.4 1.1 8.9e-11 41.3 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT50099.1 - 1.1e-06 28.0 0.0 1.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 GerE PF00196.19 EMT50099.1 - 9.8e-05 21.8 0.2 0.00017 21.1 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_ECF PF07638.11 EMT50099.1 - 0.00049 20.0 0.3 0.0011 18.9 0.3 1.6 1 1 0 1 1 1 1 ECF sigma factor KORA PF16509.5 EMT50099.1 - 0.0052 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 TrfB plasmid transcriptional repressor HTH_38 PF13936.6 EMT50099.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_antitermQ PF06530.12 EMT50099.1 - 0.027 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Phage antitermination protein Q DUF1743 PF08489.11 EMT50099.1 - 0.049 13.7 0.5 0.45 10.6 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1743) HTH_23 PF13384.6 EMT50099.1 - 0.088 12.6 0.7 0.3 10.9 0.0 2.2 3 0 0 3 3 3 0 Homeodomain-like domain DUF4179 PF13786.6 EMT50100.1 - 0.00052 20.4 0.2 0.0013 19.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) Abhydrolase_1 PF00561.20 EMT50101.1 - 7.5e-27 94.6 0.0 3.8e-23 82.4 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMT50101.1 - 4e-20 72.1 0.0 5.7e-19 68.3 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMT50101.1 - 2.3e-15 57.8 0.1 2.9e-15 57.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EMT50101.1 - 0.0018 18.1 0.1 0.22 11.3 0.0 2.8 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase DUF915 PF06028.11 EMT50101.1 - 0.0023 17.3 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 EMT50101.1 - 0.0087 15.8 0.0 0.063 13.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EMT50101.1 - 0.0095 15.7 0.0 0.75 9.5 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_4 PF08386.10 EMT50101.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Peptidase_S15 PF02129.18 EMT50101.1 - 0.018 14.6 0.1 0.21 11.1 0.1 2.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 EMT50101.1 - 0.022 14.9 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Ndr PF03096.14 EMT50101.1 - 0.024 13.4 0.0 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 Ndr family Chlorophyllase2 PF12740.7 EMT50101.1 - 0.029 13.3 0.0 0.07 12.0 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme FSH1 PF03959.13 EMT50101.1 - 0.073 12.7 0.0 13 5.4 0.0 2.8 3 0 0 3 3 3 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EMT50101.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 EMT50101.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1057 PF06342.12 EMT50101.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.25 EMT50101.1 - 0.19 11.6 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Isochorismatase PF00857.20 EMT50102.1 - 5.9e-38 130.8 0.3 7.1e-38 130.5 0.3 1.0 1 0 0 1 1 1 1 Isochorismatase family HD_5 PF13487.6 EMT50102.1 - 0.0022 18.2 0.0 0.085 13.1 0.0 2.2 2 0 0 2 2 2 1 HD domain DUF2786 PF10979.8 EMT50102.1 - 0.15 12.0 0.1 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) SKI PF01202.22 EMT50103.1 - 0.0039 17.3 0.0 0.0043 17.2 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase DUF3562 PF12085.8 EMT50103.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) ORF11CD3 PF10549.9 EMT50103.1 - 0.097 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 ORF11CD3 domain DUF4777 PF16007.5 EMT50103.1 - 0.15 12.3 0.1 0.36 11.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) YmcE_antitoxin PF15939.5 EMT50104.1 - 0.014 15.6 0.2 0.02 15.1 0.2 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system YkuD PF03734.14 EMT50105.1 - 9.7e-22 78.0 0.1 1.3e-21 77.5 0.1 1.2 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Polysacc_deac_1 PF01522.21 EMT50106.1 - 3e-37 127.3 0.0 5.9e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EMT50106.1 - 0.0081 15.8 0.3 0.11 12.2 0.2 2.5 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) CactinC_cactus PF09732.9 EMT50106.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein LPAM_1 PF08139.12 EMT50106.1 - 0.093 13.3 1.6 0.26 11.9 1.6 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DoxX PF07681.12 EMT50107.1 - 1.9e-20 73.3 14.1 1.9e-20 73.3 14.1 1.4 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 EMT50107.1 - 1.2e-05 25.3 3.8 0.00046 20.1 1.8 2.1 2 0 0 2 2 2 2 TQO small subunit DoxD DoxX_2 PF13564.6 EMT50107.1 - 1.5e-05 25.1 11.8 1.9e-05 24.7 11.8 1.2 1 0 0 1 1 1 1 DoxX-like family HxlR PF01638.17 EMT50108.1 - 4.7e-28 96.9 0.1 5.4e-28 96.7 0.1 1.0 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_5 PF01022.20 EMT50108.1 - 1.3e-06 28.2 0.1 1.9e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family PadR PF03551.14 EMT50108.1 - 0.00094 19.1 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_12 PF08461.10 EMT50108.1 - 0.0077 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_27 PF13463.6 EMT50108.1 - 0.013 16.0 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_34 PF13601.6 EMT50108.1 - 0.022 15.0 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_45 PF14947.6 EMT50108.1 - 0.089 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix MarR_2 PF12802.7 EMT50108.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 MarR family MarR PF01047.22 EMT50108.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 MarR family Peptidase_M78 PF06114.13 EMT50109.1 - 2e-10 40.6 0.0 2.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 IrrE N-terminal-like domain HTH_3 PF01381.22 EMT50110.1 - 1.2e-13 50.9 0.0 2.2e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EMT50110.1 - 3.5e-08 33.7 0.0 5.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EMT50110.1 - 4.6e-08 33.0 0.0 6.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EMT50110.1 - 3.3e-05 24.2 0.0 6.6e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EMT50110.1 - 0.00016 21.5 0.1 0.00024 20.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 EMT50110.1 - 0.00054 19.9 0.1 0.00083 19.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_8 PF02954.19 EMT50110.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_3 PF01381.22 EMT50111.1 - 7e-06 26.0 0.0 7.9e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EMT50111.1 - 8.7e-05 22.5 0.0 0.0001 22.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EMT50111.1 - 0.00072 19.8 0.0 0.00082 19.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EMT50111.1 - 0.00082 19.8 0.0 0.001 19.4 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain DeoC PF01791.9 EMT50113.1 - 0.018 14.7 0.2 0.033 13.8 0.2 1.5 1 0 0 1 1 1 0 DeoC/LacD family aldolase AP_endonuc_2 PF01261.24 EMT50113.1 - 0.07 12.6 0.0 7.1 6.0 0.0 2.9 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel PTS_EIIC PF02378.18 EMT50114.1 - 2.1e-74 250.5 39.9 2.1e-74 250.5 39.9 1.5 2 0 0 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 EMT50114.1 - 2e-14 52.8 0.4 3.5e-14 52.0 0.4 1.4 1 0 0 1 1 1 1 phosphotransferase system, EIIB CMV_1a_C PF12503.8 EMT50114.1 - 0.11 12.6 0.2 0.28 11.2 0.1 1.7 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein C terminal PEP-utilizers_C PF02896.18 EMT50115.1 - 4.1e-115 383.9 0.0 5.5e-115 383.5 0.0 1.1 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 EMT50115.1 - 1e-31 109.5 1.2 3.2e-31 107.9 0.7 2.1 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 EMT50115.1 - 2.5e-23 81.6 0.1 6.9e-23 80.2 0.1 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HpcH_HpaI PF03328.14 EMT50115.1 - 0.00096 18.4 0.0 0.0023 17.1 0.0 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Lipase_GDSL PF00657.22 EMT50115.1 - 0.11 12.4 0.1 0.39 10.7 0.0 1.9 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase SopD PF11047.8 EMT50115.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Salmonella outer protein D PTS-HPr PF00381.19 EMT50116.1 - 1.9e-27 95.3 0.1 2e-27 95.2 0.1 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site PTS_EIIA_1 PF00358.20 EMT50117.1 - 8e-52 174.3 0.4 1e-51 174.0 0.4 1.1 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Biotin_lipoyl_2 PF13533.6 EMT50117.1 - 0.017 14.9 0.2 0.017 14.9 0.2 2.6 4 0 0 4 4 4 0 Biotin-lipoyl like YqfD PF06898.11 EMT50117.1 - 0.032 13.1 0.1 0.043 12.7 0.1 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD PRD PF00874.20 EMT50118.1 - 2.6e-48 162.3 1.5 8.9e-24 83.6 1.4 2.3 2 0 0 2 2 2 2 PRD domain CAT_RBD PF03123.15 EMT50118.1 - 6.9e-19 67.5 0.0 1.4e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 CAT RNA binding domain RNaseH_like PF04308.12 EMT50119.1 - 1.6e-43 148.1 0.0 1.8e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease H-like Nitroreductase PF00881.24 EMT50120.1 - 3.2e-27 95.7 1.6 1e-14 55.0 0.3 2.1 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 EMT50120.1 - 1.1e-10 41.5 0.1 5.3e-05 22.9 0.2 2.5 2 1 1 3 3 3 2 Putative TM nitroreductase MafB19-deam PF14437.6 EMT50121.1 - 3.8e-43 146.5 0.0 4.4e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EMT50121.1 - 6e-32 109.5 0.0 7.8e-32 109.2 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 EMT50121.1 - 1.2e-05 25.4 0.2 0.00037 20.6 0.2 2.3 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 EMT50121.1 - 0.00049 20.2 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EMT50121.1 - 0.0028 17.8 0.0 0.011 15.9 0.0 1.8 1 1 1 2 2 2 1 APOBEC3 APOBEC2 PF18772.1 EMT50121.1 - 0.0064 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 EMT50121.1 - 0.01 15.9 0.0 0.022 14.9 0.0 1.5 1 1 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 EMT50121.1 - 0.028 14.3 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD1 PF18778.1 EMT50121.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 PseudoU_synth_2 PF00849.22 EMT50122.1 - 1.5e-18 67.4 0.0 2.1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EMT50122.1 - 5.9e-14 51.5 0.6 8.1e-13 47.9 0.2 2.8 2 1 1 3 3 3 1 S4 domain DUF2100 PF09873.9 EMT50122.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) DUF2089 PF09862.9 EMT50122.1 - 0.065 13.3 0.1 5.6 7.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2089) Response_reg PF00072.24 EMT50123.1 - 3.6e-16 59.3 0.0 8.2e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain BTAD PF03704.17 EMT50123.1 - 1.2e-12 48.5 1.5 3.5e-12 47.0 1.6 1.7 2 0 0 2 2 2 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 EMT50123.1 - 1.5e-07 31.4 0.3 2.9e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Big_6 PF17936.1 EMT50124.1 - 7.8e-10 38.9 11.4 1.7e-07 31.4 3.0 5.0 5 2 0 5 5 5 2 Bacterial Ig domain Laminin_G_3 PF13385.6 EMT50124.1 - 2.3e-09 37.6 13.7 7.5e-05 22.9 0.0 4.5 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily SWM_repeat PF13753.6 EMT50124.1 - 7.5e-09 35.6 0.1 7.5e-09 35.6 0.1 3.6 4 0 0 4 4 4 1 Putative flagellar system-associated repeat FIVAR PF07554.13 EMT50124.1 - 1.8e-06 28.6 5.9 5.9e-06 27.0 5.9 2.0 1 0 0 1 1 1 1 FIVAR domain CopC PF04234.12 EMT50124.1 - 0.019 16.0 4.9 0.51 11.4 0.0 4.1 2 1 1 3 3 3 0 CopC domain HU-CCDC81_euk_1 PF14908.6 EMT50124.1 - 0.02 15.0 0.4 0.054 13.6 0.0 1.9 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 1 HYR PF02494.16 EMT50124.1 - 0.37 11.1 6.6 0.16 12.3 1.0 3.4 3 0 0 3 3 3 0 HYR domain TPR_2 PF07719.17 EMT50125.1 - 3.5e-20 70.4 15.8 0.00036 20.4 0.1 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EMT50125.1 - 4.2e-19 67.5 1.1 0.006 16.9 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMT50125.1 - 5.8e-12 45.9 13.4 5.5e-05 23.6 0.0 5.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EMT50125.1 - 7.5e-12 44.5 16.4 0.0018 18.0 0.1 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EMT50125.1 - 9.3e-12 44.7 14.1 0.00034 21.2 0.0 7.8 3 2 6 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 EMT50125.1 - 1.2e-10 40.8 0.4 3.6e-06 26.5 0.0 4.0 4 0 0 4 4 4 1 TPR repeat ANAPC3 PF12895.7 EMT50125.1 - 6.6e-10 39.1 12.0 1.2e-06 28.6 1.1 4.3 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EMT50125.1 - 7.4e-09 35.1 12.5 0.09 13.0 0.1 7.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EMT50125.1 - 2.4e-08 34.5 13.4 0.0004 21.0 0.0 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMT50125.1 - 3.9e-07 30.3 20.1 0.084 13.2 0.5 6.1 3 2 4 7 7 7 4 Tetratricopeptide repeat HEAT_2 PF13646.6 EMT50125.1 - 8.7e-07 29.2 0.5 2.8e-05 24.4 0.6 3.0 2 0 0 2 2 2 1 HEAT repeats TPR_20 PF14561.6 EMT50125.1 - 9.5e-07 29.1 9.5 0.055 13.8 0.0 6.1 4 2 1 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 EMT50125.1 - 1.9e-05 24.0 8.5 0.0093 15.2 1.1 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat BTAD PF03704.17 EMT50125.1 - 0.00084 19.8 4.2 0.27 11.7 0.0 3.8 2 1 2 4 4 4 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 EMT50125.1 - 0.0013 18.8 8.8 0.21 11.8 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EMT50125.1 - 0.0021 17.7 0.7 4.9 6.8 0.1 4.0 2 2 2 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 EMT50125.1 - 0.0025 18.3 14.9 6.3 7.7 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMT50125.1 - 0.0073 16.4 10.3 0.53 10.4 0.1 4.4 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TAtT PF16811.5 EMT50125.1 - 0.019 14.3 2.7 0.051 12.9 0.8 2.5 2 0 0 2 2 2 0 TRAP transporter T-component PPR PF01535.20 EMT50125.1 - 0.023 14.9 6.7 1.9 8.9 0.1 4.9 4 0 0 4 4 4 0 PPR repeat TPR_10 PF13374.6 EMT50125.1 - 0.028 14.3 23.0 0.082 12.8 0.2 7.4 7 1 0 7 7 7 0 Tetratricopeptide repeat HTH_24 PF13412.6 EMT50125.1 - 0.041 13.4 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TPR_7 PF13176.6 EMT50125.1 - 0.044 13.8 22.6 1.9 8.7 0.1 7.6 7 2 0 7 7 7 0 Tetratricopeptide repeat HTH_28 PF13518.6 EMT50125.1 - 0.067 13.3 0.0 0.27 11.4 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain Coatomer_E PF04733.14 EMT50125.1 - 0.07 12.5 0.1 0.07 12.5 0.1 2.6 3 0 0 3 3 3 0 Coatomer epsilon subunit PPR_2 PF13041.6 EMT50125.1 - 0.086 13.1 0.9 0.47 10.7 0.0 2.8 4 0 0 4 4 1 0 PPR repeat family Pyr_redox_2 PF07992.14 EMT50126.1 - 1.5e-53 182.0 1.6 1.7e-53 181.8 1.6 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT50126.1 - 2.8e-27 95.8 1.2 8.2e-22 77.8 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMT50126.1 - 4.5e-21 75.2 3.4 8.6e-20 71.1 0.6 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMT50126.1 - 3.6e-08 32.9 1.5 0.00054 19.1 0.1 4.1 3 1 1 4 4 4 1 Glucose inhibited division protein A DAO PF01266.24 EMT50126.1 - 5e-07 29.6 2.2 0.0098 15.5 0.1 3.7 2 2 2 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 EMT50126.1 - 1.6e-06 27.6 0.1 6e-05 22.4 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EMT50126.1 - 1.8e-06 27.3 3.9 0.00083 18.5 0.1 4.1 4 1 1 5 5 5 1 FAD binding domain NAD_binding_8 PF13450.6 EMT50126.1 - 7.3e-06 26.1 0.1 0.00013 22.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMT50126.1 - 1.2e-05 24.9 7.9 1.5e-05 24.6 0.3 3.3 3 1 1 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMT50126.1 - 1.3e-05 24.1 1.7 0.0023 16.7 0.3 3.3 4 0 0 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 EMT50126.1 - 1.8e-05 24.0 0.1 0.012 14.8 0.0 2.8 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EMT50126.1 - 0.001 18.4 0.1 0.014 14.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 EMT50126.1 - 0.003 18.0 1.3 0.0075 16.7 0.6 2.1 2 1 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EMT50126.1 - 0.047 12.7 0.2 2.1 7.3 0.2 2.4 2 1 1 3 3 3 0 Lycopene cyclase protein FMO-like PF00743.19 EMT50126.1 - 0.072 11.5 0.0 0.11 10.8 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like SPESP1 PF15754.5 EMT50126.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Trp_halogenase PF04820.14 EMT50126.1 - 0.36 9.6 2.6 1.2 7.9 0.1 2.5 2 1 1 3 3 3 0 Tryptophan halogenase ATP_bind_2 PF03668.15 EMT50127.1 - 5.7e-114 380.2 0.0 6.5e-114 380.0 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_18 PF13238.6 EMT50127.1 - 0.0014 19.1 0.1 0.11 13.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMT50127.1 - 0.017 15.4 0.0 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMT50127.1 - 0.044 13.9 0.1 0.44 10.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMT50127.1 - 0.051 13.9 0.1 0.09 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 EMT50127.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain UPF0052 PF01933.18 EMT50128.1 - 2.6e-109 365.0 0.1 3.1e-109 364.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 WhiA_N PF10298.9 EMT50129.1 - 3.8e-38 129.4 2.5 1.1e-36 124.8 1.1 2.5 2 0 0 2 2 2 1 WhiA N-terminal LAGLIDADG-like domain LAGLIDADG_WhiA PF14527.6 EMT50129.1 - 1.8e-37 127.3 3.1 3.5e-36 123.1 0.1 2.7 3 0 0 3 3 3 1 WhiA LAGLIDADG-like domain HTH_WhiA PF02650.14 EMT50129.1 - 1e-34 118.7 2.4 2.8e-34 117.3 2.4 1.8 1 0 0 1 1 1 1 WhiA C-terminal HTH domain LAGLIDADG_3 PF14528.6 EMT50129.1 - 1.9e-07 31.3 0.3 8.7e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 LAGLIDADG-like domain DUF3486 PF11985.8 EMT50129.1 - 0.0089 16.5 0.1 0.018 15.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3486) zf-C4H2 PF10146.9 EMT50129.1 - 0.017 15.4 2.4 0.035 14.4 2.4 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein PTS-HPr PF00381.19 EMT50130.1 - 1.8e-30 105.0 0.5 1.9e-30 104.9 0.5 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site SspH PF08141.12 EMT50132.1 - 2.2e-22 78.9 0.6 2.4e-22 78.8 0.6 1.0 1 0 0 1 1 1 1 Small acid-soluble spore protein H family Thioredoxin_10 PF17991.1 EMT50132.1 - 0.052 14.1 0.2 0.057 14.0 0.2 1.0 1 0 0 1 1 1 0 Thioredoxin like C-terminal domain QueT PF06177.11 EMT50133.1 - 2.3e-31 109.0 19.8 2.6e-31 108.9 19.8 1.0 1 0 0 1 1 1 1 QueT transporter CLP_protease PF00574.23 EMT50134.1 - 1.9e-90 301.7 0.2 2.2e-90 301.5 0.2 1.0 1 0 0 1 1 1 1 Clp protease Bactofilin PF04519.13 EMT50135.1 - 1e-09 38.6 15.7 3e-05 24.2 1.4 3.2 1 1 2 3 3 3 3 Polymer-forming cytoskeletal RCC1_2 PF13540.6 EMT50135.1 - 0.19 11.6 0.6 12 5.9 0.1 2.6 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat zf-HC2 PF13490.6 EMT50136.1 - 1.9e-06 28.0 0.6 3.6e-06 27.1 0.6 1.5 1 0 0 1 1 1 1 Putative zinc-finger ASC PF00858.24 EMT50136.1 - 0.35 9.8 3.1 0.49 9.3 3.1 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Sigma70_r2 PF04542.14 EMT50137.1 - 7.3e-19 67.3 0.1 1.8e-18 66.0 0.1 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT50137.1 - 6.5e-17 61.0 0.0 1.2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT50137.1 - 2.3e-12 46.2 0.0 4.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT50137.1 - 0.00058 19.8 0.0 0.00085 19.3 0.0 1.5 1 1 0 1 1 1 1 ECF sigma factor HTH_AsnC-type PF13404.6 EMT50137.1 - 0.013 15.4 0.0 0.045 13.6 0.0 2.0 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain LisH_TPL PF17814.1 EMT50137.1 - 0.031 13.9 1.0 0.23 11.2 0.0 2.7 3 0 0 3 3 3 0 LisH-like dimerisation domain DUF134 PF02001.16 EMT50137.1 - 0.045 14.3 0.0 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF134 HTH_23 PF13384.6 EMT50137.1 - 0.099 12.5 0.1 1.3 8.9 0.0 2.7 2 1 0 2 2 2 0 Homeodomain-like domain Peripla_BP_6 PF13458.6 EMT50139.1 - 2.2e-51 175.5 10.8 2.7e-51 175.3 10.8 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 EMT50139.1 - 2.7e-22 79.3 0.3 3.5e-22 79.0 0.3 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 EMT50139.1 - 1.1e-06 27.9 1.7 1.1e-06 27.9 1.7 1.6 2 0 0 2 2 2 1 Periplasmic binding protein domain Glyco_tran_WecB PF03808.13 EMT50139.1 - 0.013 15.4 0.1 0.036 14.0 0.1 1.7 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Cas_Csx8 PF09657.10 EMT50139.1 - 0.032 13.3 0.7 0.044 12.8 0.7 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) DUF4023 PF13215.6 EMT50140.1 - 1.2e-15 57.2 1.9 1.4e-15 57.0 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4023) DUF4115 PF13464.6 EMT50142.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4115) Peripla_BP_2 PF01497.18 EMT50143.1 - 1.6e-34 119.5 0.1 2e-34 119.2 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Oxidored_nitro PF00148.19 EMT50143.1 - 0.0013 17.6 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase DUF3646 PF12362.8 EMT50143.1 - 0.093 13.1 0.0 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal FecCD PF01032.18 EMT50144.1 - 3.1e-92 308.9 36.7 3.7e-92 308.6 36.7 1.0 1 0 0 1 1 1 1 FecCD transport family FecCD PF01032.18 EMT50145.1 - 4e-91 305.3 34.3 4.9e-91 305.0 34.3 1.0 1 0 0 1 1 1 1 FecCD transport family Sigma54_DBD PF04552.13 EMT50146.1 - 2.9e-65 218.9 4.3 4.9e-65 218.1 4.3 1.4 1 0 0 1 1 1 1 Sigma-54, DNA binding domain Sigma54_CBD PF04963.13 EMT50146.1 - 1.1e-57 194.8 1.1 2.4e-57 193.7 0.2 2.0 2 0 0 2 2 2 1 Sigma-54 factor, core binding domain Sigma54_AID PF00309.20 EMT50146.1 - 4.9e-16 58.3 1.0 4.9e-16 58.3 1.0 2.3 2 0 0 2 2 2 1 Sigma-54 factor, Activator interacting domain (AID) HTH_Crp_2 PF13545.6 EMT50146.1 - 7.4e-06 25.8 3.4 0.0021 18.0 0.0 4.3 4 1 0 4 4 4 1 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 EMT50146.1 - 9.5e-06 25.3 0.2 0.18 11.7 0.0 3.6 3 0 0 3 3 3 2 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 EMT50146.1 - 0.00011 21.8 0.1 0.068 12.9 0.0 3.7 3 1 1 4 4 4 1 Sigma-70, region 4 HTH_6 PF01418.17 EMT50146.1 - 0.00011 22.1 0.6 1.3 9.1 0.0 3.6 3 0 0 3 3 3 2 Helix-turn-helix domain, rpiR family HTH_24 PF13412.6 EMT50146.1 - 0.00012 21.5 0.3 0.031 13.8 0.0 3.7 4 0 0 4 4 4 1 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 EMT50146.1 - 0.00036 20.5 2.6 0.01 15.9 0.0 3.5 4 0 0 4 4 3 1 Helix-turn-helix HTH_38 PF13936.6 EMT50146.1 - 0.00036 20.2 0.2 0.0037 17.0 0.0 2.7 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 EMT50146.1 - 0.00063 19.5 0.5 0.12 12.2 0.0 3.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_36 PF13730.6 EMT50146.1 - 0.00078 19.4 0.7 0.28 11.2 0.0 3.7 4 0 0 4 4 3 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 EMT50146.1 - 0.0014 18.1 2.8 0.009 15.5 0.0 3.4 4 0 0 4 4 3 1 Sigma-70, region 4 MarR PF01047.22 EMT50146.1 - 0.0015 18.4 0.0 0.0057 16.6 0.0 2.0 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EMT50146.1 - 0.0037 17.1 0.7 0.37 10.7 0.0 3.6 4 0 0 4 4 4 1 MarR family HTH_26 PF13443.6 EMT50146.1 - 0.0052 17.2 0.3 1.4 9.4 0.0 3.0 3 0 0 3 3 3 1 Cro/C1-type HTH DNA-binding domain HTH_Tnp_ISL3 PF13542.6 EMT50146.1 - 0.01 15.3 0.0 0.14 11.6 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_IclR PF09339.10 EMT50146.1 - 0.014 15.2 0.1 0.072 12.9 0.0 2.3 2 0 0 2 2 1 0 IclR helix-turn-helix domain Phage_CII PF05269.11 EMT50146.1 - 0.017 15.3 0.1 0.25 11.6 0.0 2.6 3 0 0 3 3 3 0 Bacteriophage CII protein HTH_28 PF13518.6 EMT50146.1 - 0.027 14.6 0.1 0.18 11.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_12 PF08461.10 EMT50146.1 - 0.029 14.3 0.4 5.9 6.9 0.1 3.5 2 1 1 3 3 3 0 Ribonuclease R winged-helix domain HTH_31 PF13560.6 EMT50146.1 - 0.039 14.3 0.4 0.53 10.7 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_11 PF08279.12 EMT50146.1 - 0.045 13.7 2.4 8.4 6.4 0.0 3.7 3 1 1 4 4 4 0 HTH domain HTH_29 PF13551.6 EMT50146.1 - 0.064 13.3 0.1 2.4 8.2 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn helix HTH_17 PF12728.7 EMT50146.1 - 0.069 13.4 0.2 5.4 7.3 0.0 3.1 3 0 0 3 3 2 0 Helix-turn-helix domain DUF836 PF05768.14 EMT50147.1 - 5.1e-16 58.9 0.0 5.8e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EMT50147.1 - 0.00066 19.8 1.3 0.0012 19.0 0.4 1.9 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin_3 PF13192.6 EMT50147.1 - 0.0027 17.7 0.0 0.0033 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.6 EMT50147.1 - 0.0078 16.1 0.0 0.02 14.7 0.0 1.6 1 1 1 2 2 2 1 F plasmid transfer operon protein Sugar-bind PF04198.13 EMT50148.1 - 7.3e-69 231.7 0.3 9e-69 231.4 0.3 1.1 1 0 0 1 1 1 1 Putative sugar-binding domain Metallophos_2 PF12850.7 EMT50148.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DeoRC PF00455.22 EMT50148.1 - 0.063 13.2 0.0 0.18 11.7 0.0 1.8 1 1 0 1 1 1 0 DeoR C terminal sensor domain RuvB_C PF05491.13 EMT50148.1 - 0.14 12.1 0.1 0.35 10.8 0.1 1.7 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain Na_H_antiporter PF03553.14 EMT50149.1 - 6.5e-15 55.2 41.3 1.1e-11 44.6 19.6 2.1 1 1 1 2 2 2 2 Na+/H+ antiporter family Gp_dh_C PF02800.20 EMT50150.1 - 1.3e-74 249.1 0.0 3.1e-74 247.8 0.0 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EMT50150.1 - 2.5e-41 140.1 0.7 8.1e-41 138.5 0.1 2.2 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EMT50150.1 - 5.9e-05 23.2 0.3 0.00029 21.0 0.1 2.3 1 1 1 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EMT50150.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PGK PF00162.19 EMT50151.1 - 8.1e-166 551.6 0.8 9.1e-166 551.4 0.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase TIM PF00121.18 EMT50152.1 - 2.3e-95 318.6 0.3 2.5e-95 318.5 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF3860 PF12976.7 EMT50152.1 - 0.042 13.8 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) Creatinase_N PF01321.18 EMT50152.1 - 0.05 14.2 0.2 0.94 10.1 0.0 2.6 3 0 0 3 3 3 0 Creatinase/Prolidase N-terminal domain iPGM_N PF06415.13 EMT50153.1 - 4.6e-89 297.5 0.1 6.3e-89 297.1 0.1 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EMT50153.1 - 5.1e-81 271.7 0.0 5.8e-81 271.5 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 EMT50153.1 - 0.042 13.9 0.1 0.12 12.4 0.1 1.7 2 0 0 2 2 2 0 PglZ domain DUF3213 PF11491.8 EMT50153.1 - 0.053 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Sulfatase PF00884.23 EMT50153.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Sulfatase Enolase_C PF00113.22 EMT50154.1 - 1.6e-134 447.8 0.3 2e-134 447.5 0.3 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EMT50154.1 - 1.3e-63 213.0 0.3 3e-63 211.8 0.3 1.7 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.11 EMT50154.1 - 0.00011 21.5 0.3 0.00021 20.5 0.0 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.6 EMT50154.1 - 0.00028 20.5 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like DUF4083 PF13314.6 EMT50155.1 - 6.6e-13 48.4 1.9 8.2e-13 48.1 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) Sarcoglycan_1 PF04790.13 EMT50155.1 - 0.0038 16.6 0.0 0.0042 16.5 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein Vpu PF00558.19 EMT50155.1 - 0.0047 16.7 0.1 0.006 16.3 0.1 1.1 1 0 0 1 1 1 1 Vpu protein DUF2254 PF10011.9 EMT50155.1 - 0.015 14.1 0.0 0.015 14.1 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) SUa-2TM PF18179.1 EMT50155.1 - 0.026 13.8 0.1 0.03 13.6 0.1 1.1 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain DUF4446 PF14584.6 EMT50155.1 - 0.083 12.9 0.1 0.092 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3139 PF11337.8 EMT50155.1 - 0.12 13.1 0.0 0.15 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) ODV-E18 PF10717.9 EMT50155.1 - 2.8 7.9 5.1 5.2 7.0 5.1 1.4 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 ABC_tran PF00005.27 EMT50156.1 - 2e-30 106.1 0.0 4.1e-30 105.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT50156.1 - 6.4e-10 39.3 0.1 7.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EMT50156.1 - 1.7e-08 34.6 0.0 3e-06 27.2 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 EMT50156.1 - 1.4e-06 27.9 0.0 0.031 13.7 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMT50156.1 - 8.3e-06 26.3 0.6 2.8e-05 24.6 0.6 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EMT50156.1 - 5.1e-05 22.9 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EMT50156.1 - 6.3e-05 22.0 0.2 0.02 13.7 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EMT50156.1 - 9.6e-05 22.3 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 EMT50156.1 - 0.00024 21.3 0.0 0.00046 20.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMT50156.1 - 0.00032 21.2 0.1 0.00076 20.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMT50156.1 - 0.0029 17.3 0.1 0.0043 16.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMT50156.1 - 0.0043 17.0 0.6 0.13 12.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 EMT50156.1 - 0.0047 16.8 0.3 0.013 15.4 0.1 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EMT50156.1 - 0.005 17.1 0.6 0.015 15.5 0.6 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMT50156.1 - 0.0065 16.1 0.1 0.024 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EMT50156.1 - 0.0073 16.6 0.2 0.016 15.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 EMT50156.1 - 0.0085 16.1 0.1 0.051 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EMT50156.1 - 0.027 14.1 0.0 0.099 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EMT50156.1 - 0.036 13.8 0.1 0.098 12.4 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2813 PF11398.8 EMT50156.1 - 0.042 13.1 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Zeta_toxin PF06414.12 EMT50156.1 - 0.051 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 EMT50156.1 - 0.053 13.9 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EMT50156.1 - 0.056 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PTH2 PF01981.16 EMT50156.1 - 0.062 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 SRP54 PF00448.22 EMT50156.1 - 0.069 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.25 EMT50156.1 - 0.074 12.7 0.0 0.091 12.4 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 EMT50156.1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EMT50156.1 - 0.096 12.2 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 EMT50156.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 EMT50156.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea APS_kinase PF01583.20 EMT50156.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase FecCD PF01032.18 EMT50157.1 - 1.1e-90 303.9 35.0 1.3e-90 303.6 35.0 1.0 1 0 0 1 1 1 1 FecCD transport family UPF0182 PF03699.13 EMT50157.1 - 4.7 5.2 8.4 9.5 4.2 8.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) FecCD PF01032.18 EMT50158.1 - 2e-85 286.6 31.2 2.4e-85 286.3 31.2 1.0 1 0 0 1 1 1 1 FecCD transport family Peripla_BP_2 PF01497.18 EMT50159.1 - 5.6e-32 111.2 0.3 6.7e-32 110.9 0.3 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Oxidored_nitro PF00148.19 EMT50159.1 - 0.0086 14.9 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase VanZ PF04892.12 EMT50159.1 - 0.16 12.6 0.0 0.62 10.7 0.1 1.9 2 0 0 2 2 2 0 VanZ like family Gram_pos_anchor PF00746.21 EMT50160.1 - 0.15 12.0 0.2 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Tetraspanin PF00335.20 EMT50160.1 - 0.27 10.9 1.9 0.62 9.7 1.8 1.5 1 1 0 1 1 1 0 Tetraspanin family DUF4309 PF14172.6 EMT50161.1 - 1.8e-61 206.0 3.8 2e-35 121.7 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4309) Sigma70_r2 PF04542.14 EMT50162.1 - 2.2e-18 65.8 1.6 3.3e-18 65.2 0.7 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT50162.1 - 4.8e-11 42.2 0.3 7.9e-11 41.5 0.3 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT50162.1 - 9.6e-07 28.2 0.1 1.8e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT50162.1 - 0.00029 20.8 0.3 0.00035 20.5 0.3 1.2 1 0 0 1 1 1 1 ECF sigma factor KRAB PF01352.27 EMT50162.1 - 0.13 12.0 2.4 0.26 11.0 2.4 1.5 1 0 0 1 1 1 0 KRAB box UvrD_C PF13361.6 EMT50164.1 - 6.2e-17 62.0 10.8 1.9e-10 40.7 0.1 3.6 2 2 2 4 4 4 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EMT50164.1 - 6.6e-14 52.5 0.0 4.6e-05 23.8 0.0 3.4 3 0 0 3 3 3 3 AAA domain UvrD_C_2 PF13538.6 EMT50164.1 - 3.4e-11 42.8 0.0 7e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EMT50164.1 - 2.9e-09 37.0 0.3 2.7e-05 24.0 0.3 3.2 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EMT50164.1 - 2.5e-07 30.5 9.4 2.1e-05 24.2 5.1 3.6 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 EMT50164.1 - 1.3e-05 24.7 0.2 0.068 12.6 0.0 2.8 3 0 0 3 3 3 2 PhoH-like protein DEAD PF00270.29 EMT50164.1 - 8.1e-05 22.5 0.0 0.00035 20.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EMT50164.1 - 0.00017 21.0 0.9 0.0085 15.4 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_12 PF13087.6 EMT50164.1 - 0.00038 20.1 0.0 0.00038 20.1 0.0 3.3 3 2 0 4 4 4 1 AAA domain AAA_30 PF13604.6 EMT50164.1 - 0.00091 19.0 0.0 0.005 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EMT50164.1 - 0.0013 18.7 0.0 0.0048 16.9 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 EMT50164.1 - 0.0047 16.1 0.0 0.014 14.6 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 EMT50164.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 EMT50164.1 - 1.6 8.7 8.5 1.6 8.8 0.1 3.8 3 1 2 5 5 5 0 Helicase HerA, central domain UPF0014 PF03649.13 EMT50165.1 - 1.1e-78 264.0 18.4 1.2e-78 263.8 18.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) YlaH PF14036.6 EMT50165.1 - 0.036 14.4 3.1 0.036 14.4 3.1 2.3 2 1 0 2 2 2 0 YlaH-like protein DUF5480 PF17576.2 EMT50165.1 - 0.53 10.3 0.0 0.53 10.3 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5480) ABC_tran PF00005.27 EMT50166.1 - 2.4e-26 92.9 0.0 3.1e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT50166.1 - 1.7e-05 24.8 0.3 0.15 11.8 0.3 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT50166.1 - 0.00012 21.7 0.1 0.00026 20.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT50166.1 - 0.00039 20.8 0.4 0.001 19.5 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT50166.1 - 0.00051 20.3 0.8 0.0045 17.3 0.8 2.1 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMT50166.1 - 0.0021 18.6 0.0 0.0033 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT50166.1 - 0.0024 17.8 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EMT50166.1 - 0.0033 16.9 0.0 0.55 9.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EMT50166.1 - 0.027 14.4 1.4 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EMT50166.1 - 0.047 13.4 0.1 0.73 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EMT50166.1 - 0.076 12.7 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 EMT50166.1 - 0.15 10.8 0.1 0.76 8.5 0.1 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 EMT50166.1 - 0.15 12.3 0.3 2.7 8.3 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Cytochrome_CBB3 PF13442.6 EMT50167.1 - 8e-12 45.3 0.1 1.4e-11 44.6 0.1 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EMT50167.1 - 3.2e-07 31.4 0.1 8.8e-07 30.0 0.1 1.8 1 1 0 1 1 1 1 Cytochrome c YqzM PF14141.6 EMT50167.1 - 4.7e-07 29.7 3.1 7.8e-07 29.0 3.1 1.3 1 0 0 1 1 1 1 YqzM-like protein OppC_N PF12911.7 EMT50167.1 - 0.12 12.3 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C SecG PF03840.14 EMT50168.1 - 2.6e-22 78.7 9.4 2.9e-22 78.5 9.4 1.0 1 0 0 1 1 1 1 Preprotein translocase SecG subunit SPC12 PF06645.13 EMT50168.1 - 0.9 9.7 6.8 1.7 8.8 0.4 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) RNB PF00773.19 EMT50169.1 - 4.7e-114 381.1 0.0 6.4e-114 380.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain CSD2 PF17876.1 EMT50169.1 - 9.2e-38 128.3 6.4 1e-30 105.7 1.3 3.5 3 0 0 3 3 3 2 Cold shock domain OB_RNB PF08206.11 EMT50169.1 - 2e-31 107.4 8.9 1.3e-20 72.8 0.2 3.3 3 0 0 3 3 3 2 Ribonuclease B OB domain S1 PF00575.23 EMT50169.1 - 1.5e-13 50.9 1.3 1.5e-13 50.9 1.3 2.4 2 0 0 2 2 2 1 S1 RNA binding domain OB_Dis3 PF17849.1 EMT50169.1 - 2.3e-05 24.3 0.0 5.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD PF00313.22 EMT50169.1 - 0.00024 20.9 0.4 0.042 13.7 0.0 2.7 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain RNase_II_C_S1 PF18614.1 EMT50169.1 - 0.01 15.8 0.1 0.034 14.1 0.1 1.9 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain RNA_pol_Rbc25 PF08292.12 EMT50169.1 - 0.029 14.6 0.0 0.082 13.1 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 SmpB PF01668.18 EMT50170.1 - 3.7e-62 208.4 1.6 4.3e-62 208.3 1.6 1.0 1 0 0 1 1 1 1 SmpB protein HATPase_c_3 PF13589.6 EMT50171.1 - 1.4e-16 60.5 0.0 2.9e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EMT50171.1 - 0.00069 20.1 0.0 0.0061 17.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Transposase_mut PF00872.18 EMT50172.1 - 0.076 11.9 0.0 0.091 11.6 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family HTH_29 PF13551.6 EMT50173.1 - 0.00015 21.7 0.1 0.034 14.2 0.5 2.4 2 0 0 2 2 2 2 Winged helix-turn helix HTH_28 PF13518.6 EMT50173.1 - 0.0026 17.8 0.1 1.2 9.3 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EMT50173.1 - 0.0038 17.5 2.0 0.062 13.6 2.0 2.6 1 1 0 1 1 1 1 Transposase HTH_32 PF13565.6 EMT50173.1 - 0.011 16.3 0.5 0.019 15.6 0.5 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_23 PF13384.6 EMT50173.1 - 0.018 14.9 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain DUF1027 PF06265.11 EMT50174.1 - 2.5e-37 126.7 0.6 4e-37 126.1 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1027) Spore_YhcN_YlaJ PF09580.10 EMT50175.1 - 1e-09 38.7 13.3 1e-09 38.7 13.3 2.2 1 1 1 2 2 2 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Radical_SAM PF04055.21 EMT50176.1 - 5.2e-16 59.5 0.1 7.3e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 EMT50176.1 - 3.4e-09 37.1 0.2 4.2e-08 33.6 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Sugar-bind PF04198.13 EMT50176.1 - 0.029 13.5 0.0 0.068 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative sugar-binding domain Saccharop_dh_N PF04455.12 EMT50177.1 - 9.5e-22 77.3 0.0 2.8e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region DS PF01916.17 EMT50177.1 - 0.0092 15.3 0.1 0.11 11.7 0.0 2.1 1 1 1 2 2 2 1 Deoxyhypusine synthase Tudor_4 PF18358.1 EMT50177.1 - 0.12 12.0 0.0 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain AAA_23 PF13476.6 EMT50178.1 - 7.8e-13 49.4 6.7 7.8e-13 49.4 6.7 3.5 2 2 0 2 2 1 1 AAA domain AAA_27 PF13514.6 EMT50178.1 - 2.6e-09 37.0 0.8 2.6e-09 37.0 0.8 4.9 2 2 3 5 5 5 1 AAA domain AAA_15 PF13175.6 EMT50178.1 - 8.9e-05 22.3 0.0 0.0011 18.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 EMT50178.1 - 0.0002 20.9 0.2 0.2 11.1 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EMT50178.1 - 0.0087 16.3 0.0 0.039 14.2 0.0 2.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MA3 PF02847.17 EMT50178.1 - 0.015 15.3 0.0 0.047 13.7 0.0 1.8 2 0 0 2 2 2 0 MA3 domain AAA_29 PF13555.6 EMT50178.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain UbiA PF01040.18 EMT50178.1 - 0.03 13.6 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family AAA_21 PF13304.6 EMT50178.1 - 0.085 12.6 0.0 0.28 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TMCO5 PF14992.6 EMT50178.1 - 0.095 12.3 17.1 0.019 14.6 1.3 2.6 2 0 0 2 2 2 0 TMCO5 family TPR_7 PF13176.6 EMT50178.1 - 6.8 7.0 9.1 6.4 7.1 0.2 4.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Metallophos PF00149.28 EMT50179.1 - 2.5e-12 47.8 0.7 9.6e-12 45.8 0.7 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMT50179.1 - 1.3e-08 35.2 0.1 9.1e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF111 PF01969.17 EMT50180.1 - 9.7e-91 304.6 11.1 3.4e-90 302.9 11.1 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF111 DJ-1_PfpI PF01965.24 EMT50181.1 - 4.5e-36 124.1 0.0 5.3e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EMT50181.1 - 0.00011 22.0 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EMT50181.1 - 0.0013 18.3 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 EMT50181.1 - 0.0036 17.0 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like Peptidase_C26 PF07722.13 EMT50181.1 - 0.016 15.0 0.0 0.036 13.8 0.0 1.6 1 1 0 1 1 1 0 Peptidase C26 SNO PF01174.19 EMT50181.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 1 0 1 1 1 0 SNO glutamine amidotransferase family HTS PF04204.16 EMT50181.1 - 0.19 10.6 0.0 0.39 9.6 0.0 1.5 1 1 1 2 2 2 0 Homoserine O-succinyltransferase DUF111 PF01969.17 EMT50182.1 - 5.1e-44 150.9 0.0 6.7e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF111 Transcrip_reg PF01709.20 EMT50182.1 - 0.21 10.9 0.0 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator Peptidase_M23 PF01551.22 EMT50183.1 - 1.2e-20 73.5 0.1 1.7e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M23 SLT_2 PF13406.6 EMT50183.1 - 3.9e-05 23.0 0.2 0.0039 16.5 0.1 2.1 2 0 0 2 2 2 2 Transglycosylase SLT domain TetR_N PF00440.23 EMT50184.1 - 1.2e-15 57.0 0.1 2.2e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 EMT50184.1 - 4.7e-08 33.2 0.8 4.7e-08 33.2 0.8 1.5 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 EMT50184.1 - 7.9e-07 29.3 4.4 2e-06 28.0 0.3 2.3 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 EMT50184.1 - 0.0041 17.9 1.2 0.01 16.6 0.2 2.2 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Aldedh PF00171.22 EMT50185.1 - 3.1e-145 484.3 0.1 3.9e-145 483.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EMT50185.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EMT50185.1 - 0.07 12.6 0.0 0.39 10.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Spore_GerAC PF05504.11 EMT50186.1 - 8.3e-24 84.7 0.1 2.3e-23 83.2 0.0 1.7 2 0 0 2 2 2 1 Spore germination B3/ GerAC like, C-terminal DUF2278 PF10042.9 EMT50186.1 - 0.21 11.6 0.0 0.54 10.2 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) Spore_permease PF03845.13 EMT50187.1 - 5e-51 173.4 32.3 6.4e-51 173.1 32.3 1.1 1 0 0 1 1 1 1 Spore germination protein GerA PF03323.13 EMT50188.1 - 7.2e-150 499.5 0.4 8.3e-150 499.3 0.4 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein DMRL_synthase PF00885.19 EMT50189.1 - 2.5e-62 208.9 0.2 2.8e-62 208.7 0.2 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DHBP_synthase PF00926.19 EMT50190.1 - 3.6e-86 287.6 0.8 4.8e-86 287.2 0.8 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 EMT50190.1 - 1.6e-78 262.0 0.0 4.6e-78 260.5 0.0 1.7 2 0 0 2 2 2 1 GTP cyclohydrolase II Lum_binding PF00677.17 EMT50191.1 - 4.2e-52 174.1 1.0 5.3e-25 87.2 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain RibD_C PF01872.17 EMT50192.1 - 4e-50 170.4 0.2 7.4e-50 169.6 0.2 1.4 2 0 0 2 2 2 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 EMT50192.1 - 3.2e-20 71.9 0.1 5.3e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMT50192.1 - 6.5e-12 45.4 0.1 1.1e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 EMT50192.1 - 8e-08 32.2 0.1 2.4e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Invertebrate-AID/APOBEC-deaminase NAD_binding_8 PF13450.6 EMT50193.1 - 2.6e-06 27.5 0.0 6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMT50193.1 - 0.00082 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMT50193.1 - 0.0034 16.5 0.0 0.0067 15.6 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EMT50193.1 - 0.0048 16.2 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DUF3782 PF12644.7 EMT50193.1 - 0.023 14.9 0.2 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Pyr_redox PF00070.27 EMT50193.1 - 0.19 12.3 0.0 0.42 11.2 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT50193.1 - 0.21 10.8 0.1 0.66 9.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT50193.1 - 0.21 10.3 0.0 0.38 9.4 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Spore_YunB PF09560.10 EMT50194.1 - 4.3e-30 103.6 0.3 7.2e-30 102.9 0.3 1.4 1 0 0 1 1 1 1 Sporulation protein YunB (Spo_YunB) GIDA PF01134.22 EMT50194.1 - 0.023 13.8 0.3 0.032 13.3 0.3 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A FlgT_N PF16548.5 EMT50194.1 - 0.096 13.3 1.6 0.15 12.6 1.6 1.3 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain T2SSM PF04612.12 EMT50194.1 - 0.26 11.3 2.5 0.52 10.4 0.6 2.0 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Aminotran_5 PF00266.19 EMT50196.1 - 1.5e-25 89.9 0.0 1.9e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 EMT50196.1 - 0.073 11.8 0.0 3.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain DctM PF06808.12 EMT50197.1 - 3.3e-101 339.1 53.0 3.9e-101 338.9 53.0 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component Na_H_antiporter PF03553.14 EMT50197.1 - 0.00039 19.7 5.7 0.00039 19.7 5.7 3.1 1 1 2 3 3 3 1 Na+/H+ antiporter family DctQ PF04290.12 EMT50198.1 - 1.1e-29 103.0 8.0 1.1e-29 103.0 8.0 1.5 1 1 1 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component Gemini_mov PF01708.16 EMT50198.1 - 0.14 11.9 0.5 0.34 10.7 0.5 1.6 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF3464 PF11947.8 EMT50198.1 - 3.2 7.5 6.7 0.5 10.1 2.3 1.8 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Bac_export_2 PF01312.19 EMT50198.1 - 4.8 6.3 5.3 14 4.8 5.2 1.8 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family DctP PF03480.13 EMT50199.1 - 7.5e-78 261.8 0.9 8.9e-78 261.5 0.9 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 SSB PF00436.25 EMT50199.1 - 0.039 14.0 0.1 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Single-strand binding protein family Protamine_like PF06382.11 EMT50199.1 - 0.058 13.6 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Protamine and protamine like HMGL-like PF00682.19 EMT50200.1 - 1.5e-47 162.4 0.0 1.7e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 HMGL-like CoA_transf_3 PF02515.17 EMT50201.1 - 2.9e-124 414.9 0.0 3.3e-124 414.7 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DeoC PF01791.9 EMT50201.1 - 0.084 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase FCD PF07729.12 EMT50202.1 - 2.4e-31 108.8 5.2 3.8e-31 108.1 5.2 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EMT50202.1 - 5e-19 67.7 0.5 1.1e-18 66.6 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EMT50202.1 - 7.1e-06 25.5 0.1 2.3e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EMT50202.1 - 3.2e-05 23.7 0.2 0.00028 20.7 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 EMT50202.1 - 0.00026 21.4 0.1 0.00079 19.9 0.0 1.9 2 0 0 2 2 1 1 Winged helix DNA-binding domain PaaX PF07848.12 EMT50202.1 - 0.00037 20.7 0.0 0.00093 19.4 0.0 1.6 2 0 0 2 2 1 1 PaaX-like protein HTH_11 PF08279.12 EMT50202.1 - 0.0012 18.7 0.1 0.0031 17.4 0.1 1.6 1 0 0 1 1 1 1 HTH domain Fe_dep_repress PF01325.19 EMT50202.1 - 0.0012 19.0 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 EMT50202.1 - 0.0018 18.1 0.1 0.0057 16.5 0.1 1.9 1 1 0 1 1 1 1 MarR family HTH_29 PF13551.6 EMT50202.1 - 0.0047 16.9 0.0 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix Penicillinase_R PF03965.16 EMT50202.1 - 0.0097 16.2 0.0 0.1 13.0 0.0 2.5 1 1 0 1 1 1 1 Penicillinase repressor HTH_CodY PF08222.11 EMT50202.1 - 0.012 15.1 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_5 PF01022.20 EMT50202.1 - 0.022 14.6 0.0 0.067 13.1 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_41 PF14502.6 EMT50202.1 - 0.025 14.2 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 EMT50202.1 - 0.029 14.3 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_DeoR PF08220.12 EMT50202.1 - 0.037 13.8 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain YaiA PF16362.5 EMT50202.1 - 0.055 13.6 0.2 0.59 10.3 0.1 2.3 2 0 0 2 2 2 0 YaiA protein FadR_C PF07840.12 EMT50202.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 FadR C-terminal domain Rrf2 PF02082.20 EMT50202.1 - 0.094 13.1 0.0 0.78 10.1 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator MFS_3 PF05977.13 EMT50203.1 - 9.9e-23 80.3 31.4 1.2e-22 80.0 31.4 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 EMT50203.1 - 1.4e-20 73.5 46.2 7.3e-20 71.2 35.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT50203.1 - 0.00028 19.9 24.8 0.0055 15.6 1.0 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter CDO_I PF05995.12 EMT50204.1 - 7.3e-15 54.7 0.0 8.3e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I Cupin_2 PF07883.11 EMT50204.1 - 8.7e-07 28.6 0.2 0.0075 16.0 0.0 2.2 2 0 0 2 2 2 2 Cupin domain PCO_ADO PF07847.12 EMT50204.1 - 0.0006 19.3 0.0 0.0023 17.4 0.0 1.7 1 1 0 1 1 1 1 PCO_ADO Cupin_1 PF00190.22 EMT50204.1 - 0.00068 19.3 0.2 0.00094 18.8 0.2 1.2 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 EMT50204.1 - 0.046 13.6 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Ectoine_synth PF06339.12 EMT50204.1 - 0.07 13.3 0.0 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Ectoine synthase cNMP_binding PF00027.29 EMT50205.1 - 2.1e-11 43.7 0.0 5e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 EMT50205.1 - 4.8e-06 26.5 0.1 1.1e-05 25.3 0.1 1.7 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 EMT50205.1 - 9.3e-06 25.2 0.7 1.7e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, crp family Sigma70_r4 PF04545.16 EMT50205.1 - 0.00059 19.3 0.1 0.0016 17.9 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 DUF1323 PF07037.11 EMT50205.1 - 0.11 12.8 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) Protoglobin PF11563.8 EMT50206.1 - 2.3e-44 151.1 0.5 2.3e-44 151.1 0.5 1.9 2 0 0 2 2 2 1 Protoglobin MCPsignal PF00015.21 EMT50206.1 - 9.1e-39 133.0 23.1 9.1e-39 133.0 23.1 2.8 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 EMT50206.1 - 0.0017 18.6 23.6 0.22 11.8 1.9 4.7 1 1 4 5 5 5 4 Bacterial protein of unknown function (DUF948) PSDC PF12588.8 EMT50206.1 - 0.018 15.0 0.4 0.018 15.0 0.4 2.6 2 1 1 3 3 3 0 Phophatidylserine decarboxylase Mce4_CUP1 PF11887.8 EMT50206.1 - 0.26 10.7 8.1 0.12 11.8 0.6 2.3 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative BMFP PF04380.13 EMT50206.1 - 0.48 10.9 0.1 0.48 10.9 0.1 4.3 4 1 0 4 4 4 0 Membrane fusogenic activity APG17 PF04108.12 EMT50206.1 - 0.76 8.8 22.5 0.51 9.4 12.0 2.4 2 0 0 2 2 2 0 Autophagy protein Apg17 MCM6_C PF18263.1 EMT50206.1 - 0.91 9.8 9.4 0.36 11.1 1.5 2.7 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain BLOC1_2 PF10046.9 EMT50206.1 - 1.9 8.8 29.8 0.92 9.8 4.5 4.6 3 2 2 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EMT50206.1 - 2.4 8.7 21.6 1 9.9 2.0 4.9 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein PMC2NT PF08066.12 EMT50206.1 - 3.5 8.4 9.1 1.1 10.0 1.9 3.3 2 2 0 2 2 2 0 PMC2NT (NUC016) domain Spc7 PF08317.11 EMT50206.1 - 3.6 6.4 24.9 1.7 7.4 1.5 2.7 2 0 0 2 2 2 0 Spc7 kinetochore protein AdoHcyase PF05221.17 EMT50206.1 - 4.4 6.4 11.8 0.26 10.4 1.0 2.9 3 1 1 4 4 4 0 S-adenosyl-L-homocysteine hydrolase DUF745 PF05335.13 EMT50206.1 - 7.3 6.3 33.3 0.035 13.8 5.1 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF745) CorA PF01544.18 EMT50207.1 - 9.6e-71 238.5 1.9 1.3e-70 238.0 1.9 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ni_hydr_CYTB PF01292.20 EMT50207.1 - 0.054 13.1 0.2 2.1 7.9 0.2 2.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Regulator_TrmB PF11495.8 EMT50207.1 - 0.12 11.5 0.5 0.22 10.7 0.5 1.4 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB HD PF01966.22 EMT50208.1 - 2.5e-19 69.7 0.0 4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 EMT50208.1 - 1.7e-14 53.8 0.1 3.6e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 HD domain DUF4953 PF16313.5 EMT50208.1 - 0.02 14.1 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Met-zincin DUF1805 PF08827.11 EMT50209.1 - 2.6e-22 78.9 0.8 3.5e-22 78.5 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1805) MiaE PF06175.11 EMT50210.1 - 0.012 15.3 0.2 0.013 15.2 0.2 1.0 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 5_nucleotid_C PF02872.18 EMT50211.1 - 2.9e-17 63.3 0.0 5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EMT50211.1 - 1.6e-08 35.3 1.2 2.4e-08 34.7 1.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 EMT50211.1 - 0.0037 16.7 0.1 0.015 14.7 0.1 2.1 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap TauE PF01925.19 EMT50212.1 - 9.4e-53 179.3 34.5 1.1e-52 179.0 34.5 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF72 PF01904.18 EMT50213.1 - 6.2e-66 222.6 0.4 7e-66 222.5 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 Prok-JAB PF14464.6 EMT50214.1 - 1.5e-13 50.6 0.2 1.8e-13 50.3 0.2 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Band_7 PF01145.25 EMT50215.1 - 5.6e-22 78.6 11.6 5.6e-22 78.6 11.6 4.3 1 1 1 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 EMT50215.1 - 4.9e-15 55.8 3.7 4.9e-15 55.8 3.7 5.0 4 1 1 5 5 5 1 Flotillin NfeD PF01957.18 EMT50216.1 - 1.5e-06 28.4 0.4 2.7e-06 27.6 0.4 1.4 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding SseC PF04888.12 EMT50216.1 - 0.094 12.3 0.2 0.12 11.9 0.2 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF1449 PF07290.11 EMT50216.1 - 0.22 11.1 6.2 0.43 10.2 6.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1449) DUF4131 PF13567.6 EMT50216.1 - 2.6 7.7 6.2 8.5 6.0 6.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) NUDIX PF00293.28 EMT50217.1 - 6.2e-15 55.4 0.3 7.5e-15 55.1 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_1c PF00749.21 EMT50217.1 - 0.25 10.2 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain SUFU PF05076.13 EMT50218.1 - 4.5e-07 30.0 0.0 2e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Suppressor of fused protein (SUFU) MTS PF05175.14 EMT50219.1 - 8.1e-12 45.0 0.0 2.4e-11 43.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EMT50219.1 - 8.2e-08 32.0 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EMT50219.1 - 1.7e-06 28.6 0.0 3.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT50219.1 - 4.1e-06 26.6 0.0 6.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EMT50219.1 - 0.00053 19.7 0.0 0.0036 17.0 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 EMT50219.1 - 0.00088 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 EMT50219.1 - 0.00096 19.9 0.0 0.0025 18.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 EMT50219.1 - 0.0013 19.3 0.1 0.37 11.4 0.0 2.6 1 1 1 2 2 2 1 PrmC N-terminal domain Methyltransf_23 PF13489.6 EMT50219.1 - 0.0016 18.3 0.0 0.02 14.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EMT50219.1 - 0.0018 18.1 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 EMT50219.1 - 0.0081 16.1 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT50219.1 - 0.013 16.1 0.0 0.032 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 EMT50219.1 - 0.019 14.3 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_15 PF09445.10 EMT50219.1 - 0.048 13.2 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 EMT50219.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 EMT50219.1 - 0.092 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EMT50219.1 - 0.15 11.4 0.0 0.4 10.0 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family SMI1_KNR4 PF09346.10 EMT50220.1 - 2.3e-10 41.0 0.1 3.7e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 EMT50220.1 - 8.3e-09 35.3 0.1 1.4e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 SMI1-KNR4 cell-wall SUKH_6 PF14568.6 EMT50220.1 - 2.5e-08 34.3 0.2 9.1e-08 32.6 0.2 1.9 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall UPF0051 PF01458.17 EMT50221.1 - 1e-72 244.4 0.1 1.3e-72 244.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) NifU_N PF01592.16 EMT50222.1 - 4.5e-35 120.6 0.1 1.7e-32 112.3 0.0 1.7 1 1 1 2 2 2 2 NifU-like N terminal domain TSCPD PF12637.7 EMT50222.1 - 0.021 15.1 0.1 0.055 13.7 0.1 1.6 1 1 1 2 2 2 0 TSCPD domain Aminotran_5 PF00266.19 EMT50223.1 - 8.1e-158 525.2 0.3 9.2e-158 525.0 0.3 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMT50223.1 - 1.7e-12 47.2 0.1 2.9e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMT50223.1 - 4.5e-10 38.6 1.6 3.4e-09 35.7 0.8 2.0 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EMT50223.1 - 1.4e-09 37.7 0.1 1.8e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EMT50223.1 - 1e-08 34.9 3.6 1.2e-08 34.7 2.5 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EMT50223.1 - 0.0016 17.0 0.1 0.0025 16.4 0.1 1.4 1 0 0 1 1 1 1 Methionine gamma-lyase Pyridoxal_deC PF00282.19 EMT50223.1 - 0.0081 14.9 0.1 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SelA PF03841.13 EMT50223.1 - 0.091 11.7 0.0 0.3 10.0 0.0 1.8 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase Glyco_trans_4_4 PF13579.6 EMT50223.1 - 0.16 12.4 0.3 0.34 11.4 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain UPF0051 PF01458.17 EMT50224.1 - 2.5e-62 210.4 4.1 2.5e-62 210.4 4.1 1.6 2 0 0 2 2 2 1 Uncharacterized protein family (UPF0051) ABC_tran PF00005.27 EMT50225.1 - 3e-20 73.1 0.0 4.1e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT50225.1 - 4.4e-09 36.1 0.6 7.6e-08 32.1 0.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT50225.1 - 3.9e-05 23.6 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EMT50225.1 - 0.00024 21.6 0.2 0.0098 16.3 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EMT50225.1 - 0.00055 20.5 0.1 0.23 12.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EMT50225.1 - 0.00057 19.8 0.1 0.00093 19.1 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EMT50225.1 - 0.0016 18.0 0.0 0.0027 17.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EMT50225.1 - 0.002 18.4 0.0 0.034 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMT50225.1 - 0.0026 17.4 0.1 0.0055 16.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EMT50225.1 - 0.0067 16.6 0.0 0.0097 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMT50225.1 - 0.0084 16.4 0.3 0.038 14.3 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMT50225.1 - 0.0086 16.1 0.2 3.9 7.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EMT50225.1 - 0.01 16.3 0.1 0.018 15.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMT50225.1 - 0.021 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EMT50225.1 - 0.053 13.1 0.1 0.093 12.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EMT50225.1 - 0.098 12.7 0.0 0.71 9.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 EMT50225.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 EMT50225.1 - 0.13 12.6 0.0 0.17 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 EMT50225.1 - 0.18 12.2 0.0 0.52 10.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_13 PF13166.6 EMT50225.1 - 0.27 9.8 0.0 0.38 9.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 EMT50226.1 - 1.6e-227 755.8 0.0 1.8e-227 755.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 EMT50226.1 - 0.072 13.5 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EMT50226.1 - 0.18 12.0 0.1 0.55 10.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMT50226.1 - 0.34 10.6 1.2 20 4.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain Metallophos PF00149.28 EMT50227.1 - 1.1e-15 58.7 0.0 1.6e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMT50227.1 - 1.4e-09 38.4 0.0 2.9e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 EMT50227.1 - 0.00079 17.9 0.1 0.27 9.5 0.0 2.2 1 1 1 2 2 2 2 Firmicute fructose-1,6-bisphosphatase Metallophos_3 PF14582.6 EMT50227.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Aldo_ket_red PF00248.21 EMT50228.1 - 1.8e-39 135.7 0.1 7.7e-37 127.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Fer4_17 PF13534.6 EMT50228.1 - 0.0094 16.5 7.5 0.022 15.3 7.5 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMT50228.1 - 0.33 11.1 8.0 4.7 7.4 8.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Glyoxalase PF00903.25 EMT50230.1 - 3.2e-10 40.3 0.1 3.8e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MCPsignal PF00015.21 EMT50232.1 - 5e-43 146.9 51.2 1.7e-41 141.9 22.9 4.2 1 1 4 5 5 5 4 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 EMT50232.1 - 9.9e-28 97.6 0.4 9.9e-28 97.6 0.4 4.1 2 1 0 3 3 3 1 Cache domain HAMP PF00672.25 EMT50232.1 - 7.6e-10 39.0 0.1 7.6e-10 39.0 0.1 4.0 5 0 0 5 5 5 1 HAMP domain dCache_2 PF08269.11 EMT50232.1 - 0.00017 20.9 0.1 0.00017 20.9 0.1 3.1 3 0 0 3 3 3 1 Cache domain DUF948 PF06103.11 EMT50232.1 - 0.00078 19.7 33.3 0.21 11.9 2.6 5.8 4 1 2 6 6 6 4 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 EMT50232.1 - 0.02 13.8 22.4 0.0095 14.8 2.5 2.8 1 1 1 3 3 3 0 Spc7 kinetochore protein UPF0240 PF06784.11 EMT50232.1 - 0.22 11.5 1.7 0.62 10.1 1.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) Cauli_AT PF03233.13 EMT50232.1 - 1.1 9.1 3.0 10 6.0 0.6 2.9 2 1 1 3 3 3 0 Aphid transmission protein Sec34 PF04136.15 EMT50232.1 - 1.7 8.5 17.8 0.6 10.0 2.1 4.2 3 1 1 4 4 4 0 Sec34-like family Fib_alpha PF08702.10 EMT50232.1 - 3.1 8.0 19.2 7.4 6.8 4.1 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 EMT50232.1 - 3.3 8.3 21.9 3 8.4 3.4 4.6 3 2 0 3 3 3 0 Syntaxin 6, N-terminal Acetyltransf_11 PF13720.6 EMT50232.1 - 4.5 7.8 6.8 90 3.6 0.1 4.0 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Noelin-1 PF12308.8 EMT50232.1 - 7 6.7 9.8 2.8 8.0 0.4 3.7 2 2 1 3 3 3 0 Neurogenesis glycoprotein Transposase_mut PF00872.18 EMT50233.1 - 1.7e-28 99.6 0.5 1.8e-28 99.5 0.5 1.0 1 0 0 1 1 1 1 Transposase, Mutator family SRP68 PF16969.5 EMT50233.1 - 0.015 14.3 0.1 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 TssO PF17561.2 EMT50233.1 - 0.033 14.3 1.9 0.033 14.3 1.9 1.5 2 0 0 2 2 2 0 Type VI secretion system, TssO Laps PF10169.9 EMT50233.1 - 0.063 13.9 2.8 0.1 13.2 2.8 1.3 1 0 0 1 1 1 0 Learning-associated protein HTH_23 PF13384.6 EMT50233.1 - 0.18 11.7 0.2 1.7 8.5 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain RHS_repeat PF05593.14 EMT50234.1 - 1.2e-16 60.8 51.4 9.6e-05 22.8 0.4 11.7 9 3 3 12 12 12 7 RHS Repeat Holin_BhlA PF10960.8 EMT50236.1 - 8.7e-14 51.3 0.0 1.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 BhlA holin family DUF1839 PF08893.10 EMT50236.1 - 0.05 12.8 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) Caps_synth PF05704.12 EMT50237.1 - 0.16 11.3 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein HTH_3 PF01381.22 EMT50238.1 - 1e-17 63.9 0.0 1.7e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EMT50238.1 - 1e-16 60.7 0.1 2.3e-16 59.6 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 EMT50238.1 - 1.6e-13 50.7 0.0 2.5e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EMT50238.1 - 0.00014 22.2 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EMT50238.1 - 0.00077 19.3 0.2 0.0036 17.1 0.2 2.2 1 1 0 1 1 1 1 Helix-turn-helix domain Phage_CI_repr PF07022.13 EMT50238.1 - 0.0018 18.3 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain Sigma70_r4 PF04545.16 EMT50238.1 - 0.0086 15.6 0.1 0.071 12.6 0.1 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 MarR PF01047.22 EMT50238.1 - 0.019 14.9 0.3 0.067 13.1 0.0 2.0 3 0 0 3 3 3 0 MarR family HTH_24 PF13412.6 EMT50238.1 - 0.065 12.8 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2316 PF10078.9 EMT50238.1 - 0.093 13.0 0.9 3.1 8.1 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) HTH_37 PF13744.6 EMT50238.1 - 0.1 12.6 2.4 0.13 12.2 0.1 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EMT50238.1 - 0.11 12.5 0.1 8.1 6.5 0.1 2.5 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain Peptidase_M78 PF06114.13 EMT50239.1 - 5.2e-15 55.5 0.1 6.8e-15 55.1 0.1 1.1 1 0 0 1 1 1 1 IrrE N-terminal-like domain PhetRS_B1 PF18262.1 EMT50239.1 - 0.22 11.8 0.0 0.44 10.8 0.0 1.5 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Abhydrolase_5 PF12695.7 EMT50241.1 - 5.9e-60 201.8 0.0 7.6e-60 201.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMT50241.1 - 2.3e-09 37.3 0.0 3e-06 27.1 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMT50241.1 - 2.4e-07 30.3 0.0 0.00029 20.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMT50241.1 - 0.00024 21.8 1.2 0.00044 20.9 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EMT50241.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 EMT50241.1 - 0.0019 18.4 0.2 0.0038 17.4 0.2 1.6 1 1 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 EMT50241.1 - 0.0022 17.9 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.18 EMT50241.1 - 0.023 14.2 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2974 PF11187.8 EMT50241.1 - 0.21 11.1 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) IclR PF01614.18 EMT50242.1 - 6.7e-39 132.7 0.0 1.1e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EMT50242.1 - 2.1e-11 43.5 0.0 4.3e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 EMT50242.1 - 0.001 18.9 0.1 0.012 15.4 0.0 2.7 5 0 0 5 5 5 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 EMT50242.1 - 0.0012 18.6 0.1 0.0055 16.5 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 EMT50242.1 - 0.0014 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EMT50242.1 - 0.005 16.7 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EMT50242.1 - 0.0064 16.0 0.0 0.016 14.7 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Penicillinase_R PF03965.16 EMT50242.1 - 0.011 16.0 0.0 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Penicillinase repressor Fe_dep_repress PF01325.19 EMT50242.1 - 0.012 15.8 0.0 0.039 14.2 0.0 1.9 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain LexA_DNA_bind PF01726.16 EMT50242.1 - 0.072 12.9 0.2 0.48 10.2 0.0 2.3 3 0 0 3 3 3 0 LexA DNA binding domain GatB_Yqey PF02637.18 EMT50242.1 - 0.097 12.5 0.4 0.86 9.5 0.1 2.1 2 0 0 2 2 2 0 GatB domain Rrf2 PF02082.20 EMT50242.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator Phage_int_SAM_1 PF02899.17 EMT50242.1 - 0.13 12.6 0.0 2.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain HTH_Crp_2 PF13545.6 EMT50242.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TctC PF03401.14 EMT50243.1 - 1.8e-59 201.0 0.2 2.1e-59 200.8 0.2 1.0 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter family receptor SBP_bac_8 PF13416.6 EMT50243.1 - 0.00085 19.2 2.5 0.0062 16.4 2.5 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF5569 PF17729.1 EMT50243.1 - 0.086 12.7 0.0 8.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5569) Cyclase_polyket PF04673.12 EMT50243.1 - 0.14 12.4 0.1 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 Polyketide synthesis cyclase TctB PF07331.11 EMT50244.1 - 2.4e-23 82.9 20.4 3e-23 82.6 20.4 1.0 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family DUF2070 PF09843.9 EMT50244.1 - 0.29 9.4 7.8 0.35 9.1 7.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2142 PF09913.9 EMT50244.1 - 0.94 8.3 10.5 0.17 10.7 7.1 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) Ferlin_C PF16165.5 EMT50244.1 - 1.1 9.2 2.9 2.1 8.3 2.9 1.4 1 0 0 1 1 1 0 Ferlin C-terminus DUF3040 PF11239.8 EMT50244.1 - 6.3 7.1 9.2 0.15 12.3 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) TctA PF01970.16 EMT50245.1 - 4.6e-148 493.3 43.5 5.6e-148 493.0 43.5 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctA family Nucleoporin_FG2 PF15967.5 EMT50245.1 - 0.97 7.9 11.9 2.1 6.8 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin FG repeated region PfkB PF00294.24 EMT50246.1 - 1.1e-64 218.6 0.0 1.3e-64 218.4 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EMT50246.1 - 9.2e-06 25.2 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Aldolase PF01081.19 EMT50247.1 - 5.6e-42 143.4 1.9 6.8e-42 143.1 1.9 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase TMP-TENI PF02581.17 EMT50247.1 - 0.0028 17.0 0.5 0.37 10.1 0.2 3.0 1 1 1 2 2 2 1 Thiamine monophosphate synthase DUF561 PF04481.12 EMT50247.1 - 0.045 12.9 1.1 15 4.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF561) IMPDH PF00478.25 EMT50247.1 - 0.051 12.6 1.0 0.63 9.0 0.1 2.2 2 1 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 EMT50247.1 - 0.086 12.0 3.1 0.52 9.5 0.1 2.5 1 1 2 3 3 3 0 Dihydroorotate dehydrogenase 2-Hacid_dh_C PF02826.19 EMT50248.1 - 1.8e-66 222.9 0.0 4.8e-66 221.5 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMT50248.1 - 2.4e-33 114.6 0.0 2.9e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMT50248.1 - 7.1e-07 29.5 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EMT50248.1 - 0.0017 18.9 0.0 0.0038 17.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EMT50248.1 - 0.0017 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 EMT50248.1 - 0.045 14.6 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Gp_dh_N PF00044.24 EMT50248.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.16 EMT50249.1 - 1.1e-30 106.8 48.1 2.1e-18 66.4 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT50249.1 - 1.1e-20 73.6 28.1 1.3e-20 73.4 28.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector VCH_CASS14 PF18315.1 EMT50249.1 - 0.0065 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Integron cassette protein VCH_CASS1 chain DUF1358 PF07096.11 EMT50249.1 - 0.02 14.9 0.3 0.02 14.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) MFS_4 PF06779.14 EMT50249.1 - 0.02 14.2 28.2 0.027 13.8 9.6 2.3 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EMT50249.1 - 0.085 11.7 21.3 2.1 7.1 19.0 2.9 1 1 1 2 2 2 0 MFS_1 like family Acetyltransf_18 PF18014.1 EMT50250.1 - 1.8e-25 89.2 0.0 1.9e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT50251.1 - 6.3e-10 39.1 0.0 9.9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT50251.1 - 2e-07 31.3 0.0 3.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT50251.1 - 1.7e-06 27.9 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EMT50251.1 - 3.7e-06 27.1 0.0 5.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EMT50251.1 - 0.00024 21.2 0.0 0.0028 17.7 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 EMT50251.1 - 0.00041 20.2 0.0 0.0011 18.7 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT50251.1 - 0.0082 16.2 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DM4_12 PF07841.13 EMT50251.1 - 0.037 14.7 0.0 0.066 13.9 0.0 1.4 1 0 0 1 1 1 0 DM4/DM12 family zf-CGNR PF11706.8 EMT50252.1 - 9.9e-18 63.7 7.5 1.9e-17 62.8 7.5 1.5 1 0 0 1 1 1 1 CGNR zinc finger ABATE PF07336.11 EMT50252.1 - 2.4e-16 60.6 0.0 3.7e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Putative stress-induced transcription regulator Oxidored_nitro PF00148.19 EMT50252.1 - 0.24 10.1 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DinB_2 PF12867.7 EMT50253.1 - 9.4e-12 45.6 0.1 1.2e-11 45.2 0.1 1.1 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 EMT50253.1 - 0.00015 21.7 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 DinB family PilO PF04350.13 EMT50254.1 - 3.2e-05 24.1 1.8 0.0029 17.8 0.0 2.3 2 0 0 2 2 2 2 Pilus assembly protein, PilO T2SSM PF04612.12 EMT50254.1 - 0.0076 16.3 0.1 0.019 15.1 0.1 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M T2SSM_b PF10741.9 EMT50254.1 - 0.01 15.6 0.1 0.037 13.8 0.0 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b TssO PF17561.2 EMT50254.1 - 0.64 10.1 2.6 0.82 9.8 1.3 1.8 1 1 1 2 2 2 0 Type VI secretion system, TssO PilN PF05137.13 EMT50255.1 - 2.9e-07 30.5 0.0 5.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Fimbrial assembly protein (PilN) LapA_dom PF06305.11 EMT50255.1 - 0.0086 15.9 0.6 0.0086 15.9 0.6 1.6 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain DUF4199 PF13858.6 EMT50255.1 - 0.12 12.8 0.1 0.17 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DivIC PF04977.15 EMT50255.1 - 0.86 9.4 4.7 0.18 11.6 0.6 2.0 3 0 0 3 3 3 0 Septum formation initiator PilM_2 PF11104.8 EMT50256.1 - 4.5e-19 68.7 0.1 3.2e-13 49.4 0.0 2.8 1 1 1 2 2 2 2 Type IV pilus assembly protein PilM; DiS_P_DiS PF06750.13 EMT50257.1 - 1.7e-30 105.0 0.9 1.7e-30 105.0 0.9 1.7 2 0 0 2 2 2 1 Bacterial Peptidase A24 N-terminal domain Peptidase_A24 PF01478.18 EMT50257.1 - 4.9e-19 68.7 20.0 6.1e-19 68.4 17.1 2.2 2 0 0 2 2 2 1 Type IV leader peptidase family zf_C2HC_14 PF18574.1 EMT50257.1 - 0.32 10.8 2.1 1.4 8.8 0.1 2.1 2 0 0 2 2 2 0 C2HC Zing finger domain N_methyl PF07963.12 EMT50258.1 - 5.4e-08 32.1 2.1 8.2e-08 31.5 2.1 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif MacB_PCD PF12704.7 EMT50258.1 - 0.049 14.0 0.3 0.062 13.7 0.3 1.2 1 0 0 1 1 1 0 MacB-like periplasmic core domain MFS_1_like PF12832.7 EMT50258.1 - 0.13 11.0 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 MFS_1 like family T2SSF PF00482.23 EMT50259.1 - 6.1e-59 197.4 6.6 2.3e-29 101.9 0.8 2.3 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F DUF2207 PF09972.9 EMT50259.1 - 0.00057 18.8 0.5 0.00057 18.8 0.5 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) SPX PF03105.19 EMT50259.1 - 0.097 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 SPX domain DUF3899 PF13038.6 EMT50259.1 - 0.14 12.6 3.1 64 4.2 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) T2SSE PF00437.20 EMT50260.1 - 1.3e-40 139.2 0.7 1.9e-40 138.7 0.7 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EMT50260.1 - 5.5e-05 22.6 0.2 0.013 14.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.6 EMT50260.1 - 0.00012 21.9 0.4 0.00049 19.9 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMT50260.1 - 0.00017 21.3 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT50260.1 - 0.0009 19.5 0.2 0.0025 18.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EMT50260.1 - 0.0012 18.1 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.17 EMT50260.1 - 0.0021 18.2 0.0 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 EMT50260.1 - 0.0027 18.2 0.0 0.0056 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT50260.1 - 0.0029 18.0 0.0 0.0046 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EMT50260.1 - 0.0031 18.1 0.0 0.0062 17.0 0.0 1.6 1 1 0 1 1 1 1 ABC transporter TrwB_AAD_bind PF10412.9 EMT50260.1 - 0.0064 15.5 0.1 0.031 13.2 0.1 2.0 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Rad17 PF03215.15 EMT50260.1 - 0.0073 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain ResIII PF04851.15 EMT50260.1 - 0.0088 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 EMT50260.1 - 0.009 15.9 0.8 0.76 9.7 0.3 2.4 1 1 1 2 2 2 1 NTPase ATP_bind_1 PF03029.17 EMT50260.1 - 0.0095 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SRP54 PF00448.22 EMT50260.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EMT50260.1 - 0.016 15.6 2.5 0.043 14.1 0.1 2.5 2 1 1 3 3 3 0 AAA domain TK PF00265.18 EMT50260.1 - 0.019 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase AAA_27 PF13514.6 EMT50260.1 - 0.028 14.0 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EMT50260.1 - 0.037 13.8 0.5 0.094 12.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMT50260.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 EMT50260.1 - 0.087 13.2 0.0 0.25 11.8 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EMT50260.1 - 0.097 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EMT50260.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EMT50260.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EMT50260.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 EMT50261.1 - 2e-85 286.2 3.3 3.3e-85 285.4 3.3 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 EMT50261.1 - 3.3e-27 94.9 0.9 8.9e-26 90.3 0.1 2.6 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_16 PF13191.6 EMT50261.1 - 7.2e-05 23.2 0.0 0.00017 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT50261.1 - 0.00012 22.4 0.0 0.00034 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMT50261.1 - 0.0004 20.2 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMT50261.1 - 0.00051 20.4 1.0 0.0018 18.6 0.0 2.3 3 0 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 EMT50261.1 - 0.00083 19.3 0.0 0.0041 17.1 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EMT50261.1 - 0.00085 18.9 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 EMT50261.1 - 0.00097 19.0 0.2 0.0029 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EMT50261.1 - 0.0016 18.4 0.0 0.0044 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT50261.1 - 0.0022 17.7 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT50261.1 - 0.0054 17.3 0.1 0.016 15.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EMT50261.1 - 0.0059 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EMT50261.1 - 0.0062 16.5 0.2 0.033 14.1 0.1 2.2 1 1 1 2 2 2 1 NTPase PhoH PF02562.16 EMT50261.1 - 0.011 15.2 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_21 PF13304.6 EMT50261.1 - 0.013 15.3 0.0 0.036 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EMT50261.1 - 0.016 15.6 0.0 0.062 13.7 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EMT50261.1 - 0.022 15.3 0.1 0.09 13.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Rad17 PF03215.15 EMT50261.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Herpes_ori_bp PF02399.15 EMT50261.1 - 0.026 12.6 0.0 0.042 11.9 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein ResIII PF04851.15 EMT50261.1 - 0.048 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.17 EMT50261.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF815 PF05673.13 EMT50261.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EMT50261.1 - 0.15 12.6 0.1 0.66 10.5 0.0 2.2 3 0 0 3 3 1 0 AAA domain DAP3 PF10236.9 EMT50261.1 - 0.16 11.1 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SecA_DEAD PF07517.14 EMT50261.1 - 0.28 10.5 0.8 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 SecA DEAD-like domain FumaraseC_C PF10415.9 EMT50261.1 - 0.37 11.3 1.8 31 5.1 0.0 2.9 2 1 1 3 3 2 0 Fumarase C C-terminus VanW PF04294.13 EMT50262.1 - 3.2e-28 98.0 0.0 5.2e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 VanW like protein PG_binding_4 PF12229.8 EMT50262.1 - 8.5e-14 51.8 0.1 1.5e-13 51.0 0.1 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain G5 PF07501.12 EMT50262.1 - 7.2e-06 26.4 0.1 2.4e-05 24.6 0.1 1.9 1 0 0 1 1 1 1 G5 domain N_methyl PF07963.12 EMT50264.1 - 5.4e-07 28.9 1.1 9.3e-07 28.2 1.1 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif YesK PF14150.6 EMT50264.1 - 0.052 13.8 0.1 0.086 13.0 0.1 1.3 1 0 0 1 1 1 0 YesK-like protein N_methyl PF07963.12 EMT50265.1 - 0.00011 21.6 0.4 0.00018 20.9 0.4 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Bactofilin PF04519.13 EMT50266.1 - 0.092 13.0 0.5 1.6 9.1 0.1 2.4 2 0 0 2 2 2 0 Polymer-forming cytoskeletal Cadherin-like PF12733.7 EMT50267.1 - 6.9e-18 65.0 5.7 2.5e-17 63.2 0.3 4.0 3 0 0 3 3 3 1 Cadherin-like beta sandwich domain Big_2 PF02368.18 EMT50267.1 - 8.6e-14 51.2 2.9 8.6e-14 51.2 2.9 3.3 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 2) CarboxypepD_reg PF13620.6 EMT50267.1 - 2.9e-11 43.5 3.7 1.9e-09 37.7 0.1 4.4 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EMT50267.1 - 3.4e-06 27.0 0.2 3.3e-05 23.8 0.0 2.7 2 0 0 2 2 2 1 CarboxypepD_reg-like domain DUF5018 PF16410.5 EMT50267.1 - 0.084 11.6 0.3 0.15 10.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) AA_permease PF00324.21 EMT50269.1 - 2.6e-143 478.1 44.8 2.9e-143 478.0 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMT50269.1 - 1e-46 159.6 48.4 1.5e-46 159.1 48.4 1.3 1 0 0 1 1 1 1 Amino acid permease Aminotran_1_2 PF00155.21 EMT50270.1 - 4.9e-71 239.8 0.0 5.6e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMT50270.1 - 2.7e-11 43.4 0.0 4.5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EMT50270.1 - 2.4e-07 30.0 0.0 6.2e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EMT50270.1 - 2.9e-05 23.0 0.0 4.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 EMT50270.1 - 0.00092 17.8 0.0 0.0014 17.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme AsnC_trans_reg PF01037.21 EMT50271.1 - 1.2e-13 50.8 0.8 2.8e-13 49.6 0.2 1.9 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 EMT50271.1 - 5.6e-07 29.3 3.3 1.2e-06 28.3 3.3 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 EMT50271.1 - 1.1e-05 24.9 0.9 2.4e-05 23.8 0.7 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EMT50271.1 - 0.00083 19.4 0.3 0.0015 18.6 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EMT50271.1 - 0.0021 17.9 0.3 0.0037 17.1 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 EMT50271.1 - 0.004 17.1 0.1 0.0088 16.0 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 EMT50271.1 - 0.004 17.1 0.8 0.0075 16.2 0.8 1.4 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 EMT50271.1 - 0.0069 16.2 0.4 0.22 11.4 0.3 2.8 3 0 0 3 3 3 1 Homeodomain-like domain MarR_2 PF12802.7 EMT50271.1 - 0.0082 16.0 0.4 0.024 14.5 0.4 1.8 1 0 0 1 1 1 1 MarR family DUF4423 PF14394.6 EMT50271.1 - 0.01 15.6 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) MarR PF01047.22 EMT50271.1 - 0.014 15.3 0.5 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 MarR family HTH_27 PF13463.6 EMT50271.1 - 0.016 15.7 0.1 0.039 14.4 0.1 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain GntR PF00392.21 EMT50271.1 - 0.042 13.5 0.4 0.074 12.7 0.4 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_38 PF13936.6 EMT50271.1 - 0.058 13.2 0.2 5.6 6.8 0.5 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain Phage_rep_O PF04492.13 EMT50271.1 - 0.062 13.9 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage replication protein O HTH_IclR PF09339.10 EMT50271.1 - 0.069 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.12 EMT50271.1 - 0.12 12.1 1.0 0.68 9.7 0.6 2.4 2 1 0 2 2 2 0 Sigma-70, region 4 DprA_WH PF17782.1 EMT50271.1 - 0.13 12.4 0.2 0.28 11.3 0.2 1.7 1 0 0 1 1 1 0 DprA winged helix domain Rubrerythrin PF02915.17 EMT50272.1 - 7.4e-11 42.6 0.2 1.4e-10 41.7 0.2 1.4 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 EMT50272.1 - 0.00034 20.6 0.1 0.00077 19.4 0.1 1.5 1 1 0 1 1 1 1 Ferritin-like domain DUF455 PF04305.14 EMT50272.1 - 0.0015 18.2 0.3 0.04 13.5 0.0 2.5 1 1 2 3 3 3 1 Protein of unknown function (DUF455) DUF2383 PF09537.10 EMT50272.1 - 0.0038 17.5 0.3 0.11 12.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) FA_desaturase_2 PF03405.14 EMT50272.1 - 0.093 11.6 0.1 0.51 9.1 0.0 2.0 2 0 0 2 2 2 0 Fatty acid desaturase EAL PF00563.20 EMT50273.1 - 2.6e-80 269.4 0.5 5.1e-80 268.4 0.1 1.6 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 EMT50273.1 - 6.2e-53 178.9 0.0 1.2e-52 177.9 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 EMT50273.1 - 2.7e-27 95.0 0.4 1.2e-15 57.6 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 EMT50273.1 - 3.8e-26 91.2 0.3 3.5e-14 52.8 0.1 2.6 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 EMT50273.1 - 4.2e-26 91.1 0.6 3e-12 46.6 0.2 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 EMT50273.1 - 1e-18 67.5 0.0 3e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 EMT50273.1 - 2.5e-09 36.9 0.1 0.00045 20.2 0.0 3.3 4 0 0 4 4 4 2 PAS domain PAS_11 PF14598.6 EMT50273.1 - 0.00062 19.9 0.4 0.005 17.0 0.1 2.8 2 1 1 3 3 3 1 PAS domain PAS_12 PF18095.1 EMT50273.1 - 0.08 12.6 0.1 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain HTH_20 PF12840.7 EMT50274.1 - 8e-11 41.8 0.1 2.6e-10 40.2 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EMT50274.1 - 8.1e-08 32.0 2.6 3.7e-06 26.7 0.1 3.0 3 0 0 3 3 3 1 MarR family HTH_5 PF01022.20 EMT50274.1 - 2.7e-06 27.2 1.2 3.8e-06 26.7 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_27 PF13463.6 EMT50274.1 - 6.4e-06 26.6 0.2 0.11 13.0 0.0 3.2 3 0 0 3 3 3 2 Winged helix DNA-binding domain MarR PF01047.22 EMT50274.1 - 2.1e-05 24.3 0.3 0.024 14.6 0.0 3.1 3 0 0 3 3 3 2 MarR family HTH_24 PF13412.6 EMT50274.1 - 0.0027 17.2 0.5 0.01 15.4 0.1 2.2 2 1 1 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EMT50274.1 - 0.0081 16.1 0.1 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 EMT50274.1 - 0.013 15.3 1.6 0.044 13.6 0.1 2.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain TrmB PF01978.19 EMT50274.1 - 0.042 13.7 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 EMT50274.1 - 0.042 13.5 0.0 7.3 6.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4423) HTH_28 PF13518.6 EMT50274.1 - 0.05 13.7 0.1 0.18 12.0 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1129 PF06570.11 EMT50276.1 - 0.024 14.1 4.1 0.041 13.4 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2157 PF09925.9 EMT50276.1 - 0.031 14.1 6.0 0.039 13.7 6.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF3397 PF11877.8 EMT50276.1 - 0.048 13.9 11.0 0.04 14.1 6.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) DUF3593 PF12159.8 EMT50276.1 - 0.066 13.3 6.2 0.029 14.4 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3593) TssN PF17555.2 EMT50276.1 - 0.18 11.2 12.7 0.2 11.0 12.7 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF3754 PF12576.8 EMT50276.1 - 0.22 11.5 1.8 0.25 11.3 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3754) EamA PF00892.20 EMT50276.1 - 0.24 11.6 11.2 0.067 13.4 6.1 2.0 1 1 1 2 2 2 0 EamA-like transporter family DUF420 PF04238.12 EMT50276.1 - 0.32 11.3 8.5 1.3 9.3 8.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF420) LapA_dom PF06305.11 EMT50276.1 - 0.56 10.1 0.1 0.56 10.1 0.1 3.0 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF1043 PF06295.12 EMT50276.1 - 0.63 10.1 0.1 0.63 10.1 0.1 2.2 3 0 0 3 3 2 0 Protein of unknown function (DUF1043) DUF2463 PF09591.10 EMT50276.1 - 1.1 9.1 10.6 0.035 14.0 4.8 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) DUF2070 PF09843.9 EMT50276.1 - 3.5 5.8 8.1 4.5 5.4 8.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cation_ATPase_C PF00689.21 EMT50276.1 - 3.7 7.2 12.7 1.3 8.8 0.9 2.3 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF3149 PF11346.8 EMT50276.1 - 5.4 6.7 15.2 0.21 11.2 2.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) PDR_CDR PF06422.12 EMT50276.1 - 6.7 6.7 13.8 1.7 8.6 0.2 3.4 1 1 3 4 4 4 0 CDR ABC transporter Longin_2 PF18639.1 EMT50278.1 - 0.099 12.5 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Yeast longin domain AHSA1 PF08327.11 EMT50279.1 - 1.4e-19 70.6 0.0 1.6e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EMT50279.1 - 7.9e-06 26.2 0.0 1.3e-05 25.5 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Clenterotox PF03505.14 EMT50279.1 - 0.09 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Clostridium enterotoxin DUF444 PF04285.12 EMT50280.1 - 7.5e-108 361.3 11.0 8.4e-73 245.8 0.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF444) AAA_PrkA PF08298.11 EMT50281.1 - 1.9e-146 487.6 0.0 3.3e-146 486.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain PrkA PF06798.12 EMT50281.1 - 4.5e-95 318.1 8.9 4.5e-95 318.1 8.9 2.0 2 0 0 2 2 2 1 PrkA serine protein kinase C-terminal domain AAA_16 PF13191.6 EMT50281.1 - 0.0028 18.0 0.0 0.012 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EMT50281.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Phage_T7_Capsid PF05396.11 EMT50281.1 - 0.019 15.4 0.1 0.067 13.6 0.0 1.9 2 0 0 2 2 2 0 Phage T7 capsid assembly protein Sigma54_activat PF00158.26 EMT50281.1 - 0.04 13.6 0.0 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain YppF PF14178.6 EMT50281.1 - 0.051 13.4 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 YppF-like protein UPF0180 PF03698.13 EMT50282.1 - 0.013 15.7 4.6 14 5.9 0.1 3.8 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0180) DUF2347 PF09804.9 EMT50282.1 - 1.4 8.5 20.1 2.4 7.7 1.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DUF4287 PF14117.6 EMT50282.1 - 4.5 7.5 12.7 3.5 7.8 0.3 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4287) DUF2120 PF09893.9 EMT50282.1 - 6 7.0 10.8 0.7 10.0 2.2 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) HAD_2 PF13419.6 EMT50283.1 - 1.2e-17 64.6 0.0 1.6e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMT50283.1 - 4.1e-12 46.9 0.0 3.1e-08 34.2 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMT50283.1 - 9e-08 32.1 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EMT50283.1 - 7.1e-07 29.8 0.0 1.4e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EMT50283.1 - 0.012 15.7 0.2 0.55 10.4 0.1 3.0 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMT50283.1 - 0.026 14.3 0.8 19 4.9 0.4 3.3 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase SpoU_methylase PF00588.19 EMT50284.1 - 1.6e-32 112.6 0.0 1.8e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family PALP PF00291.25 EMT50284.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Ferric_reduct PF01794.19 EMT50285.1 - 2.8e-11 43.6 8.5 2.8e-11 43.6 8.5 2.2 2 1 1 3 3 3 1 Ferric reductase like transmembrane component OST3_OST6 PF04756.13 EMT50285.1 - 2 7.7 4.8 9.8 5.4 0.6 2.5 2 1 0 2 2 2 0 OST3 / OST6 family, transporter family Amidase_6 PF12671.7 EMT50286.1 - 2.1e-32 112.5 0.1 2.1e-32 112.5 0.1 1.5 2 0 0 2 2 2 1 Putative amidase domain CHAP PF05257.16 EMT50286.1 - 0.00094 19.7 0.1 0.0049 17.4 0.1 2.2 2 0 0 2 2 2 1 CHAP domain SPECT1 PF18680.1 EMT50286.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 DNA_binding_1 PF01035.20 EMT50287.1 - 1.1e-30 105.6 0.0 1.6e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 EMT50287.1 - 1.9e-11 44.6 0.0 4.2e-11 43.5 0.0 1.5 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DUF1730 PF08331.10 EMT50288.1 - 4e-20 71.5 0.0 7.7e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1730) Fer4_16 PF13484.6 EMT50288.1 - 1.3e-15 58.1 4.7 3e-15 56.9 4.7 1.7 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain HEAT_2 PF13646.6 EMT50288.1 - 7.6e-13 48.7 0.1 2e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 HEAT repeats HEAT_PBS PF03130.16 EMT50288.1 - 8e-09 35.4 1.4 8.2e-05 22.9 0.8 2.9 2 0 0 2 2 2 2 PBS lyase HEAT-like repeat Fer4_10 PF13237.6 EMT50288.1 - 1.4e-05 25.1 3.0 0.015 15.4 0.9 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EMT50288.1 - 1.5e-05 25.1 2.4 0.0093 16.1 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 EMT50288.1 - 2.3e-05 24.0 13.3 0.00021 21.0 4.4 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain HEAT_EZ PF13513.6 EMT50288.1 - 2.3e-05 24.8 1.5 4.3e-05 23.9 0.1 2.3 2 1 0 2 2 2 1 HEAT-like repeat Fer4_6 PF12837.7 EMT50288.1 - 0.00011 22.1 9.2 0.014 15.4 3.6 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EMT50288.1 - 0.00012 22.6 9.9 0.00057 20.4 10.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 EMT50288.1 - 0.00022 21.3 7.6 0.12 12.5 2.9 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain RICTOR_V PF14668.6 EMT50288.1 - 0.0023 18.1 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 Fer4_3 PF12798.7 EMT50288.1 - 0.0032 18.3 14.1 0.099 13.6 5.3 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain HEAT PF02985.22 EMT50288.1 - 0.027 14.7 0.0 0.096 13.0 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat Fer4_2 PF12797.7 EMT50288.1 - 0.046 13.8 15.2 0.5 10.6 4.6 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain Arm PF00514.23 EMT50288.1 - 0.1 12.7 0.8 0.4 10.8 0.0 2.5 2 1 1 3 3 2 0 Armadillo/beta-catenin-like repeat Fer4_13 PF13370.6 EMT50288.1 - 0.21 12.2 6.5 2.3 8.8 2.7 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 EMT50288.1 - 0.41 11.3 9.3 6.2 7.6 2.2 2.6 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 EMT50288.1 - 0.5 10.6 10.1 0.13 12.5 3.0 2.5 1 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 EMT50288.1 - 0.65 10.5 11.6 6.8 7.2 11.7 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain SCIFF PF13165.6 EMT50288.1 - 0.73 9.8 3.8 15 5.6 0.2 2.4 2 0 0 2 2 2 0 Six-cysteine peptide SCIFF Fer4_17 PF13534.6 EMT50288.1 - 4.8 7.8 11.4 4.9 7.8 2.5 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain RNase_H PF00075.24 EMT50289.1 - 3.1e-43 147.4 0.0 3.4e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EMT50289.1 - 0.021 14.6 0.0 0.045 13.6 0.0 1.6 1 1 1 2 2 2 0 Reverse transcriptase-like B3_4 PF03483.17 EMT50290.1 - 7.9e-15 55.0 0.0 1.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain Xan_ur_permease PF00860.20 EMT50291.1 - 2.6e-60 204.2 43.7 3.2e-60 203.9 43.7 1.1 1 0 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EMT50291.1 - 0.00069 20.0 0.3 0.00069 20.0 0.3 4.4 2 2 1 4 4 4 2 Molybdate transporter of MFS superfamily DUF2157 PF09925.9 EMT50291.1 - 0.044 13.6 0.1 0.044 13.6 0.1 3.8 3 1 1 4 4 4 0 Predicted membrane protein (DUF2157) DUF4850 PF16142.5 EMT50292.1 - 8e-24 84.1 0.0 1.1e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4850) SpoIIM PF01944.17 EMT50294.1 - 4.1e-28 98.4 15.0 5.2e-28 98.0 15.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein M EI24 PF07264.11 EMT50294.1 - 0.28 11.4 13.9 0.08 13.2 6.3 2.1 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Polysacc_deac_1 PF01522.21 EMT50295.1 - 5.9e-30 103.7 0.0 9.3e-30 103.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EMT50295.1 - 5.6e-07 29.1 0.0 8.9e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 EMT50295.1 - 0.0065 16.1 0.0 0.012 15.2 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Nif11 PF07862.11 EMT50295.1 - 0.069 13.5 0.0 13 6.2 0.0 3.2 4 0 0 4 4 4 0 Nif11 domain 2-Hacid_dh_C PF02826.19 EMT50295.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KbaA PF14089.6 EMT50296.1 - 6.3e-58 195.6 16.1 7.5e-58 195.3 16.1 1.0 1 0 0 1 1 1 1 KinB-signalling pathway activation in sporulation GerD PF17898.1 EMT50297.1 - 6.3e-42 142.1 23.4 1.4e-39 134.6 16.3 2.1 1 1 1 2 2 2 2 Spore germination GerD central core domain DUF3549 PF12069.8 EMT50297.1 - 0.0018 17.4 0.7 0.0031 16.6 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3549) STI1 PF17830.1 EMT50297.1 - 0.0046 16.9 17.8 0.16 11.9 1.0 4.0 1 1 3 4 4 4 3 STI1 domain RPN13_C PF16550.5 EMT50297.1 - 0.013 15.7 3.1 0.035 14.3 1.4 2.2 1 1 1 2 2 2 0 UCH-binding domain IZUMO PF15005.6 EMT50297.1 - 2.2 8.8 12.0 5 7.6 1.9 2.6 1 1 2 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated ParA PF10609.9 EMT50298.1 - 3.3e-81 272.4 0.1 4.2e-81 272.0 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 EMT50298.1 - 8.2e-20 70.8 0.7 8.2e-20 70.8 0.7 1.7 2 0 0 2 2 1 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 EMT50298.1 - 1e-12 48.2 0.0 1.6e-12 47.6 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EMT50298.1 - 9.3e-12 45.2 0.2 2.8e-10 40.4 0.2 2.3 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 EMT50298.1 - 1.6e-07 31.1 0.0 1.5e-05 24.6 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EMT50298.1 - 5.1e-07 29.3 0.3 1.1e-06 28.1 0.1 1.7 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 EMT50298.1 - 2e-06 27.2 0.1 3.9e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EMT50298.1 - 9.4e-05 22.0 0.1 0.0078 15.7 0.1 2.3 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 EMT50298.1 - 0.00022 20.3 0.2 0.00038 19.5 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 EMT50298.1 - 0.0004 20.0 0.1 0.00075 19.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EMT50298.1 - 0.0042 16.9 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 EMT50298.1 - 0.006 15.9 0.2 0.017 14.4 0.2 1.7 2 0 0 2 2 2 1 VirC1 protein FTHFS PF01268.19 EMT50298.1 - 0.032 12.4 0.4 0.053 11.7 0.4 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase SRP54 PF00448.22 EMT50298.1 - 0.044 13.4 0.1 0.081 12.5 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Amidase_3 PF01520.18 EMT50299.1 - 1.6e-48 165.1 0.0 1.9e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Rap1_C PF11626.8 EMT50299.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ribosomal_S9 PF00380.19 EMT50300.1 - 1.9e-46 157.5 0.3 2.1e-46 157.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Flg_hook PF02120.16 EMT50300.1 - 0.0028 17.5 0.0 0.0056 16.5 0.0 1.5 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK Ribosomal_L13 PF00572.18 EMT50301.1 - 1.1e-57 193.7 0.0 1.3e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 DUF3659 PF12396.8 EMT50301.1 - 0.058 13.3 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) PseudoU_synth_1 PF01416.20 EMT50302.1 - 2.5e-44 150.2 0.0 6.5e-30 103.8 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 EMT50302.1 - 0.012 15.5 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Bactofilin PF04519.13 EMT50302.1 - 0.12 12.7 0.3 0.53 10.6 0.1 2.0 2 0 0 2 2 2 0 Polymer-forming cytoskeletal CbiQ PF02361.16 EMT50303.1 - 2.3e-54 184.3 14.7 2.9e-54 184.0 14.7 1.1 1 0 0 1 1 1 1 Cobalt transport protein DUF2614 PF11023.8 EMT50303.1 - 5.2 7.2 7.1 5.6 7.1 5.6 1.8 1 1 0 1 1 1 0 Zinc-ribbon containing domain ABC_tran PF00005.27 EMT50304.1 - 2.8e-29 102.4 0.0 5.6e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT50304.1 - 2.4e-11 44.0 0.3 7.9e-07 29.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT50304.1 - 3.6e-06 26.6 0.1 0.00013 21.5 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMT50304.1 - 7.7e-05 22.4 0.2 0.00015 21.4 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT50304.1 - 0.00021 21.6 0.3 0.0073 16.6 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT50304.1 - 0.0031 17.9 0.2 0.014 15.8 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EMT50304.1 - 0.0034 17.9 0.1 0.0056 17.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain DLIC PF05783.11 EMT50304.1 - 0.019 13.8 0.1 0.03 13.2 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 EMT50304.1 - 0.021 14.7 0.1 0.035 14.0 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EMT50304.1 - 0.026 14.1 0.2 2 7.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EMT50304.1 - 0.032 14.6 1.1 0.1 12.9 0.2 2.0 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EMT50304.1 - 0.035 13.4 0.1 0.071 12.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 EMT50304.1 - 0.04 14.0 0.1 0.1 12.7 0.1 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 EMT50304.1 - 0.042 13.8 0.4 0.14 12.1 0.0 2.0 3 0 0 3 3 3 0 NACHT domain DUF87 PF01935.17 EMT50304.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain NB-ARC PF00931.22 EMT50304.1 - 0.059 12.6 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 EMT50304.1 - 0.066 12.5 0.7 1.4 8.2 0.1 2.4 2 1 0 2 2 2 0 KaiC Adeno_IVa2 PF02456.15 EMT50304.1 - 0.069 11.9 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_30 PF13604.6 EMT50304.1 - 0.075 12.7 0.1 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EMT50304.1 - 0.099 12.3 0.0 0.75 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 EMT50304.1 - 0.12 12.1 0.0 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase MeaB PF03308.16 EMT50304.1 - 0.13 11.3 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 EMT50304.1 - 0.21 11.3 0.1 0.34 10.6 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EMT50305.1 - 1.7e-30 106.4 0.0 2.6e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT50305.1 - 4.4e-08 32.8 0.2 1.9e-06 27.5 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT50305.1 - 1e-05 25.8 0.2 8e-05 22.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT50305.1 - 0.00015 21.4 0.1 0.00031 20.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain TniB PF05621.11 EMT50305.1 - 0.00092 18.7 0.7 0.0025 17.2 0.1 2.1 3 0 0 3 3 3 1 Bacterial TniB protein AAA_33 PF13671.6 EMT50305.1 - 0.0014 18.8 0.0 0.0038 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 EMT50305.1 - 0.0031 17.7 0.1 0.14 12.5 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EMT50305.1 - 0.0031 17.9 0.0 0.0062 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 EMT50305.1 - 0.0049 17.0 0.3 0.031 14.3 0.3 2.1 1 1 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 EMT50305.1 - 0.0062 16.4 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ATPase PF06745.13 EMT50305.1 - 0.0084 15.5 0.1 0.36 10.2 0.0 2.1 1 1 1 2 2 2 1 KaiC AAA_25 PF13481.6 EMT50305.1 - 0.015 14.9 0.9 0.42 10.1 0.9 2.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMT50305.1 - 0.026 14.5 0.0 0.099 12.6 0.0 1.9 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EMT50305.1 - 0.033 13.9 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EMT50305.1 - 0.097 12.4 0.7 0.42 10.3 0.7 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EMT50305.1 - 0.11 12.9 0.1 0.18 12.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMT50305.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EMT50305.1 - 0.14 12.6 0.0 19 5.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L17 PF01196.19 EMT50306.1 - 3.9e-40 136.7 0.3 4.6e-40 136.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 DUF3306 PF11748.8 EMT50306.1 - 0.0027 18.6 0.3 0.004 18.0 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3306) NAS PF03059.16 EMT50306.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein RNA_pol_A_CTD PF03118.15 EMT50307.1 - 7.4e-30 102.5 6.0 7.9e-30 102.4 4.7 1.8 1 1 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_L PF01193.24 EMT50307.1 - 2.4e-25 87.8 0.0 6.1e-25 86.4 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 EMT50307.1 - 1.5e-24 86.5 0.5 3.6e-24 85.3 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain HHH_5 PF14520.6 EMT50307.1 - 0.044 14.4 0.2 0.27 11.9 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF211 PF02680.14 EMT50307.1 - 0.075 13.2 3.0 0.59 10.3 0.4 3.0 2 1 1 3 3 3 0 Uncharacterized ArCR, COG1888 PASTA PF03793.19 EMT50307.1 - 0.63 9.9 3.5 4.1 7.3 0.0 3.1 4 0 0 4 4 4 0 PASTA domain Ribosomal_S11 PF00411.19 EMT50308.1 - 3.2e-51 172.4 0.7 3.8e-51 172.1 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 LPD7 PF18821.1 EMT50308.1 - 0.061 13.5 0.3 0.13 12.5 0.3 1.7 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 7 E3_UbLigase_EDD PF11547.8 EMT50308.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD Ribosomal_S13 PF00416.22 EMT50309.1 - 7e-36 123.5 3.6 3e-34 118.2 3.6 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EMT50309.1 - 0.04 12.7 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Pepsin-I3 PF06394.13 EMT50309.1 - 0.055 13.7 0.1 0.079 13.2 0.1 1.2 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain SieB PF14163.6 EMT50309.1 - 0.15 11.5 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF4431 PF14485.6 EMT50309.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) Ribosomal_L36 PF00444.18 EMT50310.1 - 2.6e-19 69.1 10.2 2.8e-19 69.0 10.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 eIF-1a PF01176.19 EMT50311.1 - 2.7e-29 100.8 0.0 3e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 EMT50311.1 - 0.031 14.0 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 RsgA N-terminal domain TOBE_2 PF08402.10 EMT50311.1 - 0.051 13.7 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 TOBE domain S1 PF00575.23 EMT50311.1 - 0.062 13.7 0.1 0.2 12.0 0.1 1.7 1 1 0 1 1 1 0 S1 RNA binding domain Peptidase_M24 PF00557.24 EMT50312.1 - 1.6e-56 191.3 0.1 1.9e-56 191.1 0.1 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 ADK PF00406.22 EMT50313.1 - 4.5e-58 195.6 0.0 5.3e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EMT50313.1 - 8.5e-29 100.7 0.0 1.4e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EMT50313.1 - 1.4e-18 66.5 0.3 2.2e-18 65.9 0.3 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 EMT50313.1 - 2.2e-07 31.4 0.2 0.00085 19.7 0.2 2.2 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 EMT50313.1 - 5.4e-05 23.4 0.0 8.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMT50313.1 - 0.0006 20.4 0.1 0.0027 18.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain Prok-RING_1 PF14446.6 EMT50313.1 - 0.071 13.1 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Cytidylate_kin PF02224.18 EMT50313.1 - 0.085 12.6 0.0 0.11 12.2 0.0 1.4 2 0 0 2 2 2 0 Cytidylate kinase zf-RanBP PF00641.18 EMT50313.1 - 0.13 11.6 0.2 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-RRN7 PF11781.8 EMT50313.1 - 0.14 11.9 0.3 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 SecY PF00344.20 EMT50314.1 - 9.4e-115 383.1 31.4 1.2e-114 382.7 31.4 1.1 1 0 0 1 1 1 1 SecY translocase Ribosomal_L27A PF00828.19 EMT50315.1 - 1.4e-37 129.2 2.5 1.8e-37 128.9 2.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L30 PF00327.20 EMT50316.1 - 1.4e-22 79.3 1.7 1.6e-22 79.2 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5 PF00333.20 EMT50317.1 - 8e-32 109.0 3.0 1.2e-31 108.4 3.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EMT50317.1 - 8.1e-31 105.3 0.1 1.3e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain AAA_34 PF13872.6 EMT50317.1 - 0.055 12.3 0.1 0.073 12.0 0.1 1.1 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Ribosomal_L18p PF00861.22 EMT50318.1 - 2.5e-49 166.5 2.5 2.8e-49 166.3 2.5 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_L5e PF17144.4 EMT50318.1 - 0.02 14.9 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L6 PF00347.23 EMT50319.1 - 4.2e-42 142.7 6.0 1.3e-22 80.2 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S8 PF00410.19 EMT50320.1 - 1.4e-54 183.4 0.2 1.5e-54 183.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S14 PF00253.21 EMT50321.1 - 1.7e-25 88.5 4.2 2e-25 88.3 4.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_L5_C PF00673.21 EMT50322.1 - 2.2e-42 143.1 0.0 3.2e-42 142.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EMT50322.1 - 5.3e-28 97.1 0.9 1e-27 96.2 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 ribosomal_L24 PF17136.4 EMT50323.1 - 1.3e-30 105.6 0.4 1.3e-30 105.6 0.4 1.9 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 EMT50323.1 - 3e-09 36.5 2.1 6.1e-09 35.5 2.1 1.6 1 0 0 1 1 1 1 KOW motif Ribosomal_L14 PF00238.19 EMT50324.1 - 7e-55 184.3 2.2 7.8e-55 184.2 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_S17 PF00366.20 EMT50325.1 - 2.7e-33 113.9 2.1 2.7e-33 113.9 2.1 1.3 2 0 0 2 2 2 1 Ribosomal protein S17 BBL5 PF07289.11 EMT50325.1 - 0.028 13.5 0.1 0.031 13.3 0.1 1.0 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein Ribosomal_L29 PF00831.23 EMT50326.1 - 1.1e-24 86.2 4.0 1.2e-24 86.0 4.0 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein DUF2046 PF09755.9 EMT50326.1 - 0.0023 17.2 0.6 0.0025 17.1 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) DUF1192 PF06698.11 EMT50326.1 - 0.0055 16.7 1.7 1 9.4 0.5 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1192) DUF1664 PF07889.12 EMT50326.1 - 0.043 13.8 0.3 0.05 13.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) cwf21 PF08312.12 EMT50326.1 - 0.085 13.0 0.2 0.76 10.0 0.0 2.1 2 0 0 2 2 2 0 cwf21 domain Cnn_1N PF07989.11 EMT50326.1 - 0.4 10.9 4.2 1.1 9.5 0.8 2.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Ribosomal_L16 PF00252.18 EMT50327.1 - 5.4e-53 178.5 1.1 6e-53 178.4 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e fn3_PAP PF17808.1 EMT50327.1 - 0.085 13.0 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase Ribosomal_S3_C PF00189.20 EMT50328.1 - 1.7e-38 131.0 1.1 3.2e-38 130.1 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EMT50328.1 - 6e-20 70.9 2.7 6e-20 70.9 2.7 1.7 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 EMT50328.1 - 0.00031 20.6 0.3 0.00073 19.4 0.3 1.7 1 1 0 1 1 1 1 KH domain MRP-S24 PF14955.6 EMT50328.1 - 0.0075 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S24 LeuA_dimer PF08502.10 EMT50328.1 - 0.097 12.6 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain Ribosomal_L22 PF00237.19 EMT50329.1 - 2.7e-34 117.5 0.1 3e-34 117.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S19 PF00203.21 EMT50330.1 - 2.9e-37 126.4 0.3 3.4e-37 126.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L2_C PF03947.18 EMT50331.1 - 2.7e-57 192.4 1.2 5.9e-57 191.3 1.2 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EMT50331.1 - 2e-35 120.6 3.7 4.1e-35 119.6 3.7 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L23 PF00276.20 EMT50332.1 - 1.6e-33 114.9 4.2 1.9e-33 114.7 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 ATP-synt_D PF01813.17 EMT50332.1 - 0.026 14.3 0.1 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 ATP synthase subunit D Ubiquitin_2 PF14560.6 EMT50332.1 - 0.094 13.2 0.2 2.4 8.6 0.2 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain Ribosomal_L4 PF00573.22 EMT50333.1 - 3e-72 242.3 1.3 3.4e-72 242.2 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DLEU7 PF15760.5 EMT50333.1 - 0.2 11.1 0.6 0.4 10.1 0.6 1.5 1 1 0 1 1 1 0 Leukemia-associated protein 7 Ribosomal_L3 PF00297.22 EMT50334.1 - 7.3e-21 74.6 1.2 7.9e-18 64.6 0.2 2.4 1 1 1 2 2 2 2 Ribosomal protein L3 Ribosomal_S10 PF00338.22 EMT50335.1 - 1e-36 125.1 0.1 1.1e-36 124.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF384 PF04064.13 EMT50335.1 - 0.0034 17.2 0.1 0.007 16.2 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF384) PriA_C PF18074.1 EMT50335.1 - 0.034 15.0 0.1 0.36 11.7 0.0 2.0 1 1 1 2 2 2 0 Primosomal protein N C-terminal domain Bac_globin PF01152.21 EMT50336.1 - 3.6e-33 114.3 0.0 4.1e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 EMT50336.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Protoglobin EamA PF00892.20 EMT50337.1 - 6e-41 139.8 38.5 1.1e-23 84.0 15.5 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EMT50337.1 - 1.6e-05 24.4 6.5 0.00057 19.3 1.1 2.1 1 1 0 2 2 2 2 Triose-phosphate Transporter family Plug PF07715.15 EMT50337.1 - 0.12 12.9 0.0 0.4 11.3 0.0 1.7 1 1 1 2 2 2 0 TonB-dependent Receptor Plug Domain Sigma70_r2 PF04542.14 EMT50338.1 - 1.2e-17 63.4 0.2 3.2e-17 62.1 0.1 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT50338.1 - 7.1e-11 41.6 0.1 2e-10 40.2 0.1 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 SnoaL_2 PF12680.7 EMT50338.1 - 0.0013 19.3 0.0 0.005 17.5 0.0 2.0 1 1 0 1 1 1 1 SnoaL-like domain Sigma70_r4 PF04545.16 EMT50338.1 - 0.03 13.9 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4440 PF14534.6 EMT50338.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Amino_oxidase PF01593.24 EMT50339.1 - 1e-17 64.6 0.5 1.3e-16 61.0 0.5 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EMT50339.1 - 3.4e-13 49.9 4.1 2e-12 47.4 4.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMT50339.1 - 1.4e-11 44.5 0.8 3.7e-11 43.1 0.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMT50339.1 - 1.4e-09 37.8 1.8 2.4e-09 37.1 1.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMT50339.1 - 1e-07 31.4 2.2 1.8e-06 27.3 2.2 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EMT50339.1 - 1.2e-07 31.3 1.8 0.00011 21.6 1.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EMT50339.1 - 1.4e-07 31.1 1.0 0.005 16.1 0.5 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT50339.1 - 1.8e-05 23.7 3.6 0.0045 15.7 1.2 2.5 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 EMT50339.1 - 9.4e-05 22.9 1.3 0.0045 17.5 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMT50339.1 - 0.0011 18.2 0.8 0.0029 16.7 0.8 1.7 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMT50339.1 - 0.0022 17.3 0.5 0.26 10.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMT50339.1 - 0.01 15.1 0.2 0.019 14.2 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EMT50339.1 - 0.014 14.4 0.8 0.14 11.2 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 EMT50339.1 - 0.051 13.1 0.7 0.094 12.3 0.7 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GTP_EFTU PF00009.27 EMT50340.1 - 2.4e-61 206.7 0.1 3.2e-61 206.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EMT50340.1 - 1.1e-33 115.9 1.6 1.3e-33 115.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EMT50340.1 - 1.4e-19 70.2 4.4 3e-19 69.2 4.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMT50340.1 - 8.2e-06 25.9 0.0 1.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EMT50340.1 - 0.011 15.3 0.1 0.039 13.5 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EMT50340.1 - 0.058 13.3 0.0 0.18 11.7 0.0 1.9 1 1 1 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EMT50341.1 - 9.8e-68 227.5 0.2 1.5e-67 226.9 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EMT50341.1 - 4.8e-48 161.9 0.1 1.1e-47 160.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EMT50341.1 - 1.4e-36 124.4 0.2 3.3e-36 123.2 0.2 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EMT50341.1 - 5e-32 109.8 0.1 1.9e-31 108.0 0.1 2.1 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMT50341.1 - 2.1e-15 56.8 0.4 7e-15 55.2 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EMT50341.1 - 2e-06 27.6 0.0 4.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EMT50341.1 - 0.00015 21.8 0.0 0.00041 20.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EMT50341.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Ribosomal_S7 PF00177.21 EMT50342.1 - 4.2e-68 227.7 0.9 4.7e-68 227.5 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.25 EMT50343.1 - 4.3e-38 129.4 2.1 4.7e-38 129.3 1.3 1.5 1 1 1 2 2 2 1 Ribosomal protein S12/S23 Ribosomal_L7Ae PF01248.26 EMT50344.1 - 1.6e-18 66.3 2.0 1.8e-18 66.1 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Peptidase_S76 PF13611.6 EMT50344.1 - 0.056 13.8 0.2 0.063 13.6 0.2 1.1 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 SpoU_sub_bind PF08032.12 EMT50344.1 - 0.067 13.5 0.1 0.098 12.9 0.1 1.4 1 1 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Glutaredoxin PF00462.24 EMT50344.1 - 0.078 13.2 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 Glutaredoxin RNA_pol_Rpb1_1 PF04997.12 EMT50345.1 - 1.5e-90 303.7 0.0 2.5e-90 303.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EMT50345.1 - 4.3e-68 229.6 3.3 1.2e-65 221.7 3.3 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EMT50345.1 - 2.6e-41 141.6 0.0 2.9e-38 131.7 0.0 2.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EMT50345.1 - 8.6e-33 113.5 0.0 2e-32 112.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EMT50345.1 - 5.8e-16 58.4 0.2 1.7e-15 56.9 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Peptidase_M23 PF01551.22 EMT50345.1 - 0.073 13.3 0.2 1.8 8.8 0.0 2.9 2 0 0 2 2 2 0 Peptidase family M23 ApbA_C PF08546.11 EMT50345.1 - 0.11 12.7 0.4 0.53 10.5 0.1 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal RNA_pol_Rpb2_6 PF00562.28 EMT50346.1 - 1.4e-169 564.3 0.0 3.4e-169 563.0 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.14 EMT50346.1 - 1.6e-40 138.8 0.6 8.6e-30 103.8 0.1 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 EMT50346.1 - 5e-31 106.7 0.0 1.2e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 EMT50346.1 - 6.5e-31 107.4 0.0 2.3e-30 105.7 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EMT50346.1 - 1.1e-27 96.2 0.0 2.4e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_45 PF10385.9 EMT50346.1 - 1.9e-26 92.1 0.1 3.7e-25 88.0 0.2 3.1 2 0 0 2 2 2 1 RNA polymerase beta subunit external 1 domain MTS PF05175.14 EMT50347.1 - 2e-51 173.9 0.0 2.2e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EMT50347.1 - 7.2e-19 68.1 0.0 1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT50347.1 - 6.1e-13 49.3 0.0 1e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMT50347.1 - 8.9e-13 48.3 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EMT50347.1 - 1.3e-08 35.4 0.0 5e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EMT50347.1 - 1.2e-07 31.6 0.0 1.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 EMT50347.1 - 2e-07 31.0 0.2 2.7e-07 30.6 0.2 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 EMT50347.1 - 5.6e-07 29.5 0.0 7.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 EMT50347.1 - 7.6e-07 29.1 0.0 9.6e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT50347.1 - 1e-06 28.3 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 EMT50347.1 - 2.2e-06 27.7 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT50347.1 - 8.7e-06 26.4 0.0 1.4e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EMT50347.1 - 3e-05 23.4 0.1 5.6e-05 22.5 0.1 1.4 1 1 1 2 2 2 1 rRNA small subunit methyltransferase G DUF43 PF01861.16 EMT50347.1 - 3.1e-05 23.3 0.0 4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain CMAS PF02353.20 EMT50347.1 - 4.5e-05 22.9 0.0 5.8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 EMT50347.1 - 8.1e-05 22.3 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 EMT50347.1 - 0.00012 21.9 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase N6_Mtase PF02384.16 EMT50347.1 - 0.00033 20.0 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.18 EMT50347.1 - 0.00043 20.0 0.1 0.00065 19.4 0.1 1.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 TehB PF03848.14 EMT50347.1 - 0.00052 19.5 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB TRM PF02005.16 EMT50347.1 - 0.0015 17.8 0.0 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_4 PF02390.17 EMT50347.1 - 0.003 17.0 0.1 0.005 16.3 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 EMT50347.1 - 0.0033 17.4 0.0 0.0057 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EMT50347.1 - 0.0034 17.0 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F SPOUT_MTase_2 PF14419.6 EMT50347.1 - 0.0051 16.2 0.2 0.007 15.8 0.2 1.2 1 0 0 1 1 1 1 AF2226-like SPOUT RNA Methylase fused to THUMP Methyltransf_15 PF09445.10 EMT50347.1 - 0.0072 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.11 EMT50347.1 - 0.0098 14.9 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase FmrO PF07091.11 EMT50347.1 - 0.014 15.0 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_3 PF01596.17 EMT50347.1 - 0.02 14.1 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.20 EMT50347.1 - 0.023 13.8 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GCV_H PF01597.19 EMT50347.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage H-protein TrkA_N PF02254.18 EMT50347.1 - 0.069 13.4 0.2 0.15 12.3 0.1 1.7 2 0 0 2 2 1 0 TrkA-N domain FtsJ PF01728.19 EMT50347.1 - 0.093 12.8 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.12 EMT50347.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PRMT5 PF05185.16 EMT50347.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Ribosomal_L12 PF00542.19 EMT50348.1 - 2.1e-31 108.1 6.0 2.1e-31 108.1 6.0 2.1 2 1 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EMT50348.1 - 3.6e-21 74.6 8.1 3.6e-21 74.6 8.1 2.7 3 0 0 3 3 3 2 Ribosomal protein L7/L12 dimerisation domain Ribosomal_L10 PF00466.20 EMT50349.1 - 1e-29 102.6 1.0 1.4e-29 102.2 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Amidohydro_1 PF01979.20 EMT50349.1 - 0.026 13.9 0.8 0.15 11.4 0.3 1.9 1 1 1 2 2 2 0 Amidohydrolase family DNA_photolyase PF00875.18 EMT50349.1 - 0.026 14.5 0.3 0.16 12.0 0.3 1.9 1 1 0 1 1 1 0 DNA photolyase Hydrolase_6 PF13344.6 EMT50349.1 - 0.027 14.6 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribosomal_L1 PF00687.21 EMT50350.1 - 2.5e-57 193.9 0.0 3.4e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L11_N PF03946.14 EMT50351.1 - 6.7e-33 112.3 0.3 1.1e-32 111.6 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EMT50351.1 - 1.3e-26 92.8 1.2 2.1e-26 92.2 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NusG PF02357.19 EMT50352.1 - 5.9e-30 103.6 0.5 9.9e-30 102.9 0.1 1.5 2 0 0 2 2 2 1 Transcription termination factor nusG KOW PF00467.29 EMT50352.1 - 6.8e-08 32.2 0.1 1.7e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 KOW motif CopK PF11525.8 EMT50352.1 - 0.015 14.9 0.4 0.033 13.8 0.4 1.5 1 0 0 1 1 1 0 Copper resistance protein K SecE PF00584.20 EMT50353.1 - 1.1e-23 82.9 1.8 1.3e-23 82.6 1.8 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex SafA PF17073.5 EMT50353.1 - 0.0036 17.2 0.1 0.0043 17.0 0.1 1.2 1 0 0 1 1 1 1 Two-component-system connector protein Ribosomal_L33 PF00471.20 EMT50354.1 - 1.5e-20 73.4 9.3 1.6e-20 73.2 9.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 Sigma70_r2 PF04542.14 EMT50355.1 - 5.4e-14 51.7 0.1 1.2e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT50355.1 - 2.3e-09 36.8 0.5 4.1e-09 36.0 0.5 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 GerE PF00196.19 EMT50355.1 - 1.8e-05 24.1 0.1 2.9e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 EMT50355.1 - 0.0012 18.6 0.1 0.0024 17.6 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_16 PF12645.7 EMT50355.1 - 0.0014 18.7 0.3 0.0043 17.1 0.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 EMT50355.1 - 0.0026 17.5 0.1 0.006 16.3 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 EMT50355.1 - 0.031 14.3 0.1 0.075 13.1 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Terminase_5 PF06056.12 EMT50355.1 - 0.11 12.4 0.1 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) DUF1676 PF07898.13 EMT50355.1 - 0.13 12.3 0.2 0.36 10.9 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1676) NYN_YacP PF05991.11 EMT50356.1 - 3.2e-53 180.1 1.0 3.7e-53 179.9 1.0 1.0 1 0 0 1 1 1 1 YacP-like NYN domain cwf21 PF08312.12 EMT50356.1 - 0.0032 17.6 0.0 4.5 7.5 0.0 2.5 2 1 0 2 2 2 2 cwf21 domain NTS PF15447.6 EMT50356.1 - 0.0088 16.5 0.4 0.029 14.9 0.0 2.1 2 0 0 2 2 2 1 N-terminal segments of PfEMP1 YflT PF11181.8 EMT50356.1 - 0.023 15.2 0.8 0.042 14.4 0.8 1.5 1 0 0 1 1 1 0 Heat induced stress protein YflT Oxidored_nitro PF00148.19 EMT50356.1 - 0.035 12.9 0.0 0.35 9.6 0.0 1.9 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase LUD_dom PF02589.15 EMT50356.1 - 0.042 13.6 0.3 0.064 13.0 0.3 1.2 1 0 0 1 1 1 0 LUD domain SWIRM-assoc_1 PF16495.5 EMT50356.1 - 0.052 13.5 1.1 0.23 11.4 0.3 2.1 2 0 0 2 2 2 0 SWIRM-associated region 1 SpoU_methylase PF00588.19 EMT50357.1 - 1.1e-38 132.7 0.0 1.6e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EMT50357.1 - 2.6e-23 82.1 0.0 6.6e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Ribonuclease_3 PF00636.26 EMT50358.1 - 1.3e-15 57.9 0.1 1.6e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease III domain tRNA-synt_1e PF01406.19 EMT50359.1 - 9.3e-139 461.9 0.0 7.2e-138 459.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EMT50359.1 - 3e-18 65.8 0.0 4.2e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EMT50359.1 - 7.6e-17 61.5 0.2 2.1e-16 60.2 0.2 1.8 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.22 EMT50359.1 - 8.7e-09 34.2 0.0 1.1e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 EMT50359.1 - 7e-08 31.8 0.0 0.00048 19.2 0.0 2.6 2 1 1 3 3 3 2 tRNA synthetases class I (K) Hexapep PF00132.24 EMT50360.1 - 1.9e-16 59.1 10.1 8.6e-09 34.8 1.3 2.7 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) SATase_N PF06426.14 EMT50360.1 - 7.4e-07 29.5 0.1 3.2e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Serine acetyltransferase, N-terminal Hexapep_2 PF14602.6 EMT50360.1 - 9.4e-05 22.1 16.1 0.0047 16.7 3.6 3.8 4 1 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase ZapB PF06005.12 EMT50360.1 - 0.0074 16.7 0.2 0.011 16.1 0.2 1.2 1 0 0 1 1 1 1 Cell division protein ZapB tRNA-synt_1c PF00749.21 EMT50361.1 - 9.8e-117 389.3 0.0 1.2e-116 389.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 EMT50361.1 - 0.023 13.6 0.0 3.3 6.5 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (K) CobN-Mg_chel PF02514.16 EMT50361.1 - 0.032 12.0 0.1 0.08 10.7 0.1 1.5 2 0 0 2 2 2 0 CobN/Magnesium Chelatase DsrC PF04358.13 EMT50361.1 - 0.089 13.3 0.2 2.7 8.5 0.1 2.8 3 0 0 3 3 3 0 DsrC like protein Tox-HNH-HHH PF15637.6 EMT50361.1 - 0.14 12.3 0.0 22 5.3 0.0 2.5 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif YgbB PF02542.16 EMT50362.1 - 2e-65 219.8 0.0 2.3e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 YgbB family IspD PF01128.19 EMT50363.1 - 1.4e-74 250.6 0.3 1.6e-74 250.4 0.3 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 EMT50363.1 - 4.2e-17 63.0 0.9 5.4e-17 62.6 0.9 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EMT50363.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.3 1 1 0 1 1 1 0 Nucleotidyl transferase PIN_9 PF18477.1 EMT50364.1 - 1.1e-05 25.7 0.1 2.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 PIN like domain TRAM PF01938.20 EMT50364.1 - 3.3e-05 23.8 0.3 3.3e-05 23.8 0.3 1.9 2 0 0 2 2 2 1 TRAM domain PIN PF01850.21 EMT50364.1 - 0.001 19.5 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 PIN domain PIN_4 PF13638.6 EMT50364.1 - 0.0012 19.1 0.3 0.0019 18.5 0.3 1.3 1 0 0 1 1 1 1 PIN domain PIN_5 PF08745.11 EMT50364.1 - 0.016 14.7 0.4 0.098 12.1 0.1 2.1 1 1 1 3 3 3 0 PINc domain ribonuclease MORN PF02493.20 EMT50364.1 - 0.63 10.1 1.9 0.68 9.9 0.1 2.0 2 0 0 2 2 2 0 MORN repeat Cauli_DNA-bind PF03310.13 EMT50365.1 - 0.00038 20.5 0.1 0.00055 20.0 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus DNA-binding protein MazG PF03819.17 EMT50365.1 - 0.0047 17.1 0.1 0.0075 16.4 0.1 1.5 1 1 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain CtIP_N PF10482.9 EMT50365.1 - 0.058 13.4 1.1 0.1 12.6 0.9 1.7 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain PCYCGC PF13798.6 EMT50365.1 - 0.075 12.9 0.1 0.084 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif CDP-OH_P_transf PF01066.21 EMT50366.1 - 1e-15 58.2 0.1 1e-15 58.2 0.1 2.9 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DisA-linker PF10635.9 EMT50367.1 - 1.5e-54 183.7 5.7 2.1e-54 183.2 5.7 1.2 1 0 0 1 1 1 1 DisA bacterial checkpoint controller linker region DisA_N PF02457.16 EMT50367.1 - 2.8e-25 88.2 0.0 5.5e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 DisA bacterial checkpoint controller nucleotide-binding HHH_2 PF12826.7 EMT50367.1 - 2.7e-08 33.8 0.5 4.9e-07 29.7 0.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.23 EMT50367.1 - 3.3e-05 23.5 0.1 0.00011 21.8 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EMT50367.1 - 0.00077 20.0 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.6 EMT50368.1 - 1.6e-17 63.7 0.3 7.7e-17 61.5 0.3 2.1 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 EMT50368.1 - 2.5e-17 63.0 1.3 2.7e-09 36.7 0.1 2.2 1 1 0 2 2 2 2 KaiC Rubredoxin_2 PF18073.1 EMT50368.1 - 1.1e-13 50.7 6.8 1.6e-13 50.1 6.8 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain ChlI PF13541.6 EMT50368.1 - 3.7e-11 42.9 0.1 1.1e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase Lon_C PF05362.13 EMT50368.1 - 1.2e-09 38.0 2.3 1.6e-08 34.3 0.2 2.2 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain DnaB_C PF03796.15 EMT50368.1 - 8.7e-06 25.2 0.0 2.1e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EMT50368.1 - 0.00047 20.6 0.3 0.0011 19.3 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EMT50368.1 - 0.00053 19.8 0.0 0.0025 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMT50368.1 - 0.0023 18.2 0.0 0.0058 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EMT50368.1 - 0.0054 16.7 0.3 0.094 12.6 0.1 2.8 2 1 0 2 2 2 1 NTPase AAA PF00004.29 EMT50368.1 - 0.0055 17.1 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad51 PF08423.11 EMT50368.1 - 0.011 15.0 0.6 0.14 11.4 0.6 2.2 1 1 0 1 1 1 0 Rad51 NACHT PF05729.12 EMT50368.1 - 0.018 15.0 0.3 0.041 13.8 0.3 1.7 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EMT50368.1 - 0.037 13.8 0.2 0.11 12.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EMT50368.1 - 0.078 12.7 0.2 0.22 11.2 0.2 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.23 EMT50368.1 - 0.082 13.0 0.0 0.25 11.4 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 EMT50368.1 - 0.11 12.2 0.6 1.6 8.5 0.2 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EMT50368.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EMT50368.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain HypA PF01155.19 EMT50368.1 - 0.27 11.3 1.5 0.66 10.0 0.9 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA AAA_2 PF07724.14 EMT50369.1 - 1.6e-60 204.1 0.4 1.1e-57 194.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EMT50369.1 - 7.3e-38 128.7 3.3 2.8e-37 126.8 3.3 2.1 1 0 0 1 1 1 1 AAA lid domain Clp_N PF02861.20 EMT50369.1 - 1.5e-34 117.9 9.5 1.3e-17 63.7 0.3 3.5 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component ClpB_D2-small PF10431.9 EMT50369.1 - 6.2e-28 96.7 0.8 6.2e-28 96.7 0.8 2.9 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EMT50369.1 - 8.7e-27 94.1 0.1 2.4e-13 50.6 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMT50369.1 - 1.1e-18 67.6 0.4 1.3e-12 47.9 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EMT50369.1 - 5.5e-12 45.7 0.0 5.1e-07 29.5 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 EMT50369.1 - 3.5e-11 43.8 9.2 8.5e-05 23.0 0.0 4.8 4 2 0 6 6 4 2 AAA ATPase domain AAA_22 PF13401.6 EMT50369.1 - 2.3e-09 37.6 5.4 0.01 16.1 0.1 5.8 3 2 1 4 4 4 2 AAA domain IstB_IS21 PF01695.17 EMT50369.1 - 2.9e-08 33.6 0.0 0.0024 17.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EMT50369.1 - 9.1e-08 32.2 0.1 0.03 14.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain UVR PF02151.19 EMT50369.1 - 1.7e-07 30.7 7.1 8e-07 28.6 7.1 2.3 1 0 0 1 1 1 1 UvrB/uvrC motif TniB PF05621.11 EMT50369.1 - 2.1e-07 30.5 0.0 0.00035 20.0 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 EMT50369.1 - 4e-07 30.6 1.7 0.28 11.8 0.0 4.6 3 1 1 4 4 4 2 AAA domain RuvB_N PF05496.12 EMT50369.1 - 4.7e-06 26.4 2.3 0.28 10.9 0.0 4.3 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EMT50369.1 - 8.4e-06 25.3 0.2 0.68 9.3 0.0 3.7 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EMT50369.1 - 2.1e-05 24.6 9.7 0.42 10.5 0.1 4.6 3 2 1 4 4 4 3 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EMT50369.1 - 9.3e-05 22.0 0.0 0.31 10.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Roc PF08477.13 EMT50369.1 - 9.9e-05 22.6 0.0 0.8 9.9 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EMT50369.1 - 0.00011 22.4 0.0 0.52 10.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 EMT50369.1 - 0.00013 21.8 0.2 0.14 11.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EMT50369.1 - 0.00014 22.2 0.1 0.72 10.3 0.0 3.1 3 0 0 3 3 3 2 RNA helicase ResIII PF04851.15 EMT50369.1 - 0.00029 20.9 0.0 1.9 8.5 0.0 4.1 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit NACHT PF05729.12 EMT50369.1 - 0.0003 20.8 0.0 0.27 11.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 EMT50369.1 - 0.00046 20.1 0.2 1.1 9.1 0.0 3.3 3 1 1 4 4 4 1 RsgA GTPase DNA_pol3_delta2 PF13177.6 EMT50369.1 - 0.00049 19.9 0.0 0.062 13.1 0.0 3.2 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Zeta_toxin PF06414.12 EMT50369.1 - 0.00049 19.4 0.0 0.27 10.5 0.0 3.0 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 EMT50369.1 - 0.00053 20.0 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 EMT50369.1 - 0.00062 20.3 21.9 0.00072 20.1 0.2 3.5 2 2 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EMT50369.1 - 0.00069 19.5 0.1 0.37 10.7 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 EMT50369.1 - 0.001 19.2 0.0 0.14 12.2 0.0 2.8 2 0 0 2 2 2 1 Torsin NB-ARC PF00931.22 EMT50369.1 - 0.0017 17.6 0.0 0.46 9.6 0.0 2.8 2 0 0 2 2 2 1 NB-ARC domain TIP49 PF06068.13 EMT50369.1 - 0.0022 17.3 1.9 1.2 8.3 0.1 3.8 3 1 1 4 4 4 1 TIP49 P-loop domain AAA_28 PF13521.6 EMT50369.1 - 0.0023 18.2 0.0 3.5 7.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EMT50369.1 - 0.0038 16.7 0.5 7.5 6.0 0.0 3.7 4 0 0 4 4 4 0 PhoH-like protein KTI12 PF08433.10 EMT50369.1 - 0.0074 15.8 0.0 4.1 6.8 0.0 3.3 3 0 0 3 3 3 1 Chromatin associated protein KTI12 NTPase_1 PF03266.15 EMT50369.1 - 0.028 14.3 0.4 13 5.6 0.0 3.2 3 0 0 3 3 2 0 NTPase ABC_tran PF00005.27 EMT50369.1 - 0.034 14.7 0.8 6.7 7.2 0.0 3.2 3 1 0 3 3 2 0 ABC transporter AAA_25 PF13481.6 EMT50369.1 - 0.094 12.3 0.0 3.8 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EMT50369.1 - 0.097 12.4 0.8 16 5.2 0.1 3.5 4 0 0 4 4 3 0 Cytidylate kinase YfcL PF08891.11 EMT50369.1 - 0.51 10.7 2.5 14 6.2 0.0 3.5 2 1 0 2 2 2 0 YfcL protein AAA_19 PF13245.6 EMT50369.1 - 0.61 10.4 2.6 6.7 7.0 0.2 3.5 2 2 0 3 3 3 0 AAA domain ATP-gua_Ptrans PF00217.19 EMT50370.1 - 6.8e-72 241.4 0.9 9.3e-72 240.9 0.9 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain UVR PF02151.19 EMT50371.1 - 6.6e-09 35.2 8.8 9.7e-09 34.7 8.8 1.3 1 0 0 1 1 1 1 UvrB/uvrC motif zf-C2H2_3 PF13878.6 EMT50371.1 - 0.14 12.0 0.2 0.14 12.0 0.2 2.9 3 1 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO PhnA_Zn_Ribbon PF08274.12 EMT50371.1 - 1.9 8.5 7.8 21 5.2 0.1 3.8 4 0 0 4 4 4 0 PhnA Zinc-Ribbon Nudix_N_2 PF14803.6 EMT50371.1 - 2.4 8.2 9.2 0.37 10.7 1.3 3.0 3 0 0 3 3 3 0 Nudix N-terminal CtsR PF05848.11 EMT50372.1 - 1.8e-36 123.8 1.4 2.7e-36 123.3 0.7 1.6 2 0 0 2 2 2 1 CtsR N-terminal HTH domain CtsR_C PF17727.1 EMT50372.1 - 7.6e-22 77.2 3.2 1.3e-21 76.4 3.2 1.4 1 0 0 1 1 1 1 CtsR C-terminal dimerization domain ATP-grasp_6 PF18419.1 EMT50372.1 - 0.11 12.1 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp-like domain HAD_2 PF13419.6 EMT50373.1 - 5.7e-26 91.7 0.0 6.8e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EMT50373.1 - 2.3e-15 57.5 0.0 3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMT50373.1 - 1.8e-12 48.0 0.1 2.3e-11 44.4 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMT50373.1 - 2.2e-06 27.6 0.1 4.1e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EMT50373.1 - 4e-06 26.9 0.0 0.062 13.4 0.0 2.9 2 2 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMT50373.1 - 0.00018 21.3 0.0 0.033 13.9 0.0 3.0 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EMT50373.1 - 0.015 15.1 0.0 0.81 9.5 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase DUF4331 PF14224.6 EMT50373.1 - 0.031 13.5 0.0 0.031 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4331) Put_Phosphatase PF06888.12 EMT50373.1 - 0.073 12.5 0.0 0.28 10.5 0.0 2.0 1 1 1 2 2 2 0 Putative Phosphatase MGDG_synth PF06925.11 EMT50374.1 - 5.1e-30 104.8 1.4 8e-30 104.2 1.4 1.3 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 EMT50374.1 - 7.4e-08 32.5 0.1 1.4e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.20 EMT50374.1 - 5e-06 26.2 0.0 9.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 EMT50374.1 - 0.00065 18.7 0.0 0.00099 18.1 0.0 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase HisK_N PF09385.10 EMT50374.1 - 0.0025 17.8 0.6 0.0095 15.9 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase N terminal DUF2179 PF10035.9 EMT50374.1 - 0.0094 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2179) Ntox47 PF15540.6 EMT50375.1 - 1.5e-45 154.1 0.8 3.7e-45 152.8 0.8 1.7 1 0 0 1 1 1 1 Bacterial toxin 47 MT0933_antitox PF14013.6 EMT50375.1 - 0.033 14.5 0.3 0.033 14.5 0.3 3.9 4 1 0 4 4 4 0 MT0933-like antitoxin protein DUF3316 PF11777.8 EMT50375.1 - 0.096 12.7 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) ApoLp-III PF07464.11 EMT50375.1 - 0.81 9.8 4.2 5.8 7.0 0.2 3.2 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) LysE PF01810.18 EMT50376.1 - 4.5e-37 127.4 10.7 5.3e-37 127.2 10.7 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 EMT50376.1 - 0.0032 17.2 1.9 0.0032 17.2 1.9 1.9 1 1 1 2 2 2 1 Integral membrane protein TerC family DUF373 PF04123.13 EMT50376.1 - 0.34 10.3 2.9 0.55 9.6 2.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Phage_holin_3_6 PF07332.11 EMT50376.1 - 2.4 8.2 13.5 2.4 8.2 3.4 2.5 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III VKOR PF07884.14 EMT50376.1 - 3.2 8.0 11.2 6.2 7.0 2.2 2.4 2 0 0 2 2 2 0 Vitamin K epoxide reductase family DHHC PF01529.20 EMT50376.1 - 8 6.6 10.2 5 7.2 5.5 2.5 1 1 2 3 3 3 0 DHHC palmitoyltransferase Formyl_trans_N PF00551.19 EMT50378.1 - 2.8e-41 141.2 0.1 4e-41 140.7 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 EMT50378.1 - 2.4e-08 33.6 0.0 5.8e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EMT50378.1 - 0.036 14.1 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 ACT domain ACT_4 PF13291.6 EMT50378.1 - 0.042 14.4 0.0 0.12 13.0 0.0 1.7 2 0 0 2 2 2 0 ACT domain Glutaredoxin PF00462.24 EMT50378.1 - 0.18 12.1 0.8 1 9.6 0.0 2.5 3 0 0 3 3 3 0 Glutaredoxin Glyoxalase PF00903.25 EMT50379.1 - 1.5e-07 31.7 0.0 5.5e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EMT50379.1 - 0.0084 16.9 0.0 0.011 16.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EMT50379.1 - 0.036 14.0 0.0 0.077 12.9 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase-like domain CppA_N PF14506.6 EMT50379.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 2 0 0 2 2 2 0 CppA N-terminal DUF779 PF05610.11 EMT50380.1 - 5.2e-50 167.7 0.0 6.1e-50 167.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF779) Aldedh PF00171.22 EMT50381.1 - 1.7e-166 554.3 0.0 1.9e-166 554.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 EMT50381.1 - 0.016 15.2 0.3 0.049 13.6 0.3 1.8 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated ADH_N PF08240.12 EMT50382.1 - 4.6e-36 123.0 2.8 4.6e-36 123.0 2.8 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMT50382.1 - 1.5e-31 109.1 0.6 2.3e-31 108.5 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMT50382.1 - 4.3e-07 31.0 0.3 6.8e-07 30.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMT50382.1 - 0.00038 19.8 2.5 0.00061 19.1 2.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CoA_binding PF02629.19 EMT50382.1 - 0.0018 18.9 2.3 0.11 13.2 0.7 2.7 2 0 0 2 2 2 1 CoA binding domain 2-Hacid_dh_C PF02826.19 EMT50382.1 - 0.0035 16.7 0.1 0.0057 16.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EMT50382.1 - 0.0046 17.6 0.1 0.013 16.2 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT50382.1 - 0.018 15.7 0.2 0.14 12.8 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 EMT50382.1 - 0.024 14.9 0.5 0.05 13.9 0.5 1.5 1 0 0 1 1 1 0 TrkA-N domain ADH_N_2 PF16884.5 EMT50382.1 - 0.029 14.3 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase AP_endonuc_2 PF01261.24 EMT50382.1 - 0.068 12.6 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel PglD_N PF17836.1 EMT50382.1 - 0.1 13.3 1.9 0.11 13.1 0.6 1.8 2 0 0 2 2 2 0 PglD N-terminal domain Fe-ADH PF00465.19 EMT50383.1 - 1.8e-119 398.8 1.7 2e-119 398.7 1.7 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMT50383.1 - 9.7e-19 68.0 2.6 5.9e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase HATPase_c PF02518.26 EMT50384.1 - 2.3e-17 63.5 0.0 5e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT50384.1 - 1.1e-16 60.6 0.4 7.3e-16 58.0 0.0 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF1018 PF06252.12 EMT50384.1 - 0.0008 20.4 0.4 0.0059 17.6 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1018) HATPase_c_5 PF14501.6 EMT50384.1 - 0.012 15.5 0.0 0.05 13.5 0.0 2.1 2 1 0 2 2 2 0 GHKL domain GAF_3 PF13492.6 EMT50384.1 - 0.064 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 GAF domain HATPase_c_3 PF13589.6 EMT50384.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sigma54_activat PF00158.26 EMT50385.1 - 8e-63 211.1 0.1 1.2e-62 210.5 0.1 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT50385.1 - 2.3e-20 73.1 0.0 2e-19 70.1 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain Response_reg PF00072.24 EMT50385.1 - 2.8e-20 72.6 0.0 5.9e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Mg_chelatase PF01078.21 EMT50385.1 - 1.8e-06 27.5 0.1 0.00036 20.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI HTH_8 PF02954.19 EMT50385.1 - 4.8e-06 26.3 0.2 1.5e-05 24.6 0.2 1.9 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 EMT50385.1 - 1.2e-05 25.3 0.0 3.6e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMT50385.1 - 2.2e-05 24.7 0.0 3.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EMT50385.1 - 0.00049 20.5 0.0 0.0013 19.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 EMT50385.1 - 0.026 14.4 0.0 0.065 13.1 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EMT50385.1 - 0.035 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2220 PF09983.9 EMT50385.1 - 0.041 13.3 0.1 0.093 12.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) MCM PF00493.23 EMT50385.1 - 0.048 12.7 0.0 0.26 10.4 0.0 2.1 2 1 0 2 2 2 0 MCM P-loop domain Gp-FAR-1 PF05823.12 EMT50385.1 - 0.089 13.1 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) HTH_10 PF04967.12 EMT50385.1 - 0.13 12.0 0.3 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain TetR_N PF00440.23 EMT50386.1 - 9.9e-17 60.5 1.0 1.7e-16 59.7 1.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 EMT50386.1 - 2.7e-05 24.5 0.4 9.8e-05 22.6 0.4 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 EMT50386.1 - 0.0011 19.1 0.1 0.0033 17.6 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase TetR_C_24 PF17932.1 EMT50386.1 - 0.0016 18.7 0.4 0.0044 17.3 0.1 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Sigma70_ECF PF07638.11 EMT50386.1 - 0.0027 17.6 0.3 0.71 9.7 0.0 2.2 2 0 0 2 2 2 2 ECF sigma factor TetR_C_17 PF17922.1 EMT50386.1 - 0.031 14.4 0.2 0.072 13.2 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Sigma70_r4_2 PF08281.12 EMT50386.1 - 0.039 13.6 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 TetR_C_10 PF16295.5 EMT50386.1 - 0.051 13.9 0.3 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HrcA_DNA-bdg PF03444.15 EMT50386.1 - 0.088 12.5 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Sigma54_CBD PF04963.13 EMT50386.1 - 0.14 12.0 2.0 0.36 10.7 2.0 1.7 1 1 0 1 1 1 0 Sigma-54 factor, core binding domain ABC2_membrane_3 PF12698.7 EMT50387.1 - 6.2e-48 163.7 14.1 7.5e-48 163.4 14.1 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 EMT50387.1 - 2.3e-34 118.6 27.1 9.1e-32 110.2 19.6 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 EMT50387.1 - 1.7e-22 80.1 10.6 2.4e-22 79.6 10.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 EMT50387.1 - 0.00013 22.0 22.3 0.00018 21.6 14.2 3.1 2 1 1 3 3 3 2 ABC-2 family transporter protein DUF2938 PF11158.8 EMT50387.1 - 0.017 14.6 0.8 0.035 13.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) ABC_tran PF00005.27 EMT50388.1 - 1.8e-30 106.3 0.0 2.4e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT50388.1 - 3.4e-11 43.5 0.6 1.6e-06 28.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMT50388.1 - 0.00025 21.6 0.0 0.00038 21.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EMT50388.1 - 0.00049 19.6 0.0 0.012 15.1 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT50388.1 - 0.0018 18.1 0.0 1.2 8.7 0.0 2.2 1 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EMT50388.1 - 0.0036 17.0 0.3 0.0073 16.0 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CLP1_P PF16575.5 EMT50388.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 EMT50388.1 - 0.048 14.1 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 EMT50388.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EMT50388.1 - 0.089 12.9 0.1 0.15 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMT50388.1 - 0.22 11.5 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain HlyD_3 PF13437.6 EMT50389.1 - 2.8e-20 73.0 11.7 1e-17 64.8 0.3 3.3 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 EMT50389.1 - 6.5e-20 71.3 23.2 3.9e-18 65.5 9.6 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 EMT50389.1 - 1.9e-10 40.4 4.4 1.2e-09 37.8 3.0 5.2 6 1 0 6 6 6 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 EMT50389.1 - 8.8e-06 25.5 1.6 0.00074 19.3 0.7 2.8 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD PF00529.20 EMT50389.1 - 0.0013 18.5 13.5 1.3 9.0 13.0 3.1 1 1 1 2 2 2 2 HlyD membrane-fusion protein of T1SS DUF2353 PF09789.9 EMT50389.1 - 0.041 13.2 7.7 0.056 12.8 7.7 1.4 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) CSD2 PF17876.1 EMT50389.1 - 0.044 14.0 0.1 0.14 12.4 0.1 1.9 1 0 0 1 1 1 0 Cold shock domain HlyD_2 PF12700.7 EMT50389.1 - 0.18 10.5 3.7 0.77 8.4 0.3 2.6 2 1 0 2 2 2 0 HlyD family secretion protein SHOCT PF09851.9 EMT50389.1 - 0.61 9.9 2.9 1.4 8.7 0.5 2.6 2 0 0 2 2 2 0 Short C-terminal domain DUF3006 PF11213.8 EMT50389.1 - 1.3 9.3 5.1 4.7 7.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3006) Spc7 PF08317.11 EMT50389.1 - 2 7.2 18.3 0.36 9.7 14.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein TFIIA PF03153.13 EMT50389.1 - 2.3 8.1 14.7 2.9 7.8 14.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TSNAXIP1_N PF15739.5 EMT50389.1 - 5.2 7.5 15.1 6.5 7.2 4.1 3.0 2 2 1 3 3 3 0 Translin-associated factor X-interacting N-terminus OEP PF02321.18 EMT50389.1 - 7.9 6.2 44.2 9.3 6.0 0.9 3.5 1 1 2 3 3 3 0 Outer membrane efflux protein MeMO_Hyd_G PF02964.16 EMT50389.1 - 9.3 6.2 10.5 0.82 9.7 4.4 2.3 2 1 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain DUF402 PF04167.13 EMT50390.1 - 8.8e-20 70.7 2.1 1.3e-19 70.1 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF402) FTP PF07504.13 EMT50391.1 - 1.6e-05 24.6 0.3 0.15 11.9 0.1 3.2 3 0 0 3 3 3 2 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 EMT50391.1 - 0.0036 17.8 0.1 8.3 7.1 0.0 3.8 3 0 0 3 3 3 2 Peptidase propeptide and YPEB domain DUF4901 PF16244.5 EMT50391.1 - 0.004 16.6 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4901) IMS_C PF11799.8 EMT50391.1 - 0.09 13.5 0.0 0.32 11.7 0.0 1.9 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Sigma70_r2 PF04542.14 EMT50392.1 - 6e-21 74.0 1.7 1.1e-20 73.2 1.7 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT50392.1 - 9.7e-14 50.8 1.2 2.2e-13 49.6 1.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT50392.1 - 3.9e-06 26.3 1.2 7.3e-06 25.4 0.4 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT50392.1 - 0.00015 21.8 1.2 0.00022 21.2 1.2 1.3 1 1 0 1 1 1 1 ECF sigma factor HTH_17 PF12728.7 EMT50392.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4901 PF16244.5 EMT50393.1 - 2.6e-10 40.1 1.7 0.001 18.5 0.0 4.5 2 2 0 2 2 2 2 Domain of unknown function (DUF4901) PepSY PF03413.19 EMT50393.1 - 4.5e-08 33.5 10.7 0.0001 22.8 1.0 5.7 5 2 0 5 5 5 2 Peptidase propeptide and YPEB domain MT0933_antitox PF14013.6 EMT50393.1 - 1.3 9.3 4.6 70 3.8 0.0 4.0 3 0 0 3 3 3 0 MT0933-like antitoxin protein UvrD-helicase PF00580.21 EMT50394.1 - 8.2e-79 265.4 0.0 1.8e-78 264.3 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EMT50394.1 - 7.1e-29 101.3 0.0 3.1e-27 95.9 0.0 3.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EMT50394.1 - 5.7e-22 78.6 0.2 1e-20 74.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EMT50394.1 - 3.8e-11 42.6 1.2 1.7e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 EMT50394.1 - 8.9e-10 38.9 5.0 2e-09 37.7 0.1 3.3 3 0 0 3 3 3 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 EMT50394.1 - 0.00042 20.1 0.1 2.2 8.0 0.0 3.8 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 EMT50394.1 - 0.0035 17.1 0.0 0.0087 15.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_12 PF13087.6 EMT50394.1 - 0.0043 16.7 0.0 0.013 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMT50394.1 - 0.005 16.6 0.2 0.015 15.0 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT50394.1 - 0.011 16.2 0.4 0.076 13.4 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 EMT50394.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PDDEXK_1 PF12705.7 EMT50395.1 - 4.7e-60 203.6 0.1 9.7e-58 196.1 0.0 2.6 2 0 0 2 2 2 2 PD-(D/E)XK nuclease superfamily UvrD_C PF13361.6 EMT50395.1 - 2.3e-08 33.8 0.0 0.0054 16.1 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Exonuc_V_gamma PF04257.14 EMT50395.1 - 8.2e-08 31.0 0.0 2.4e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Exodeoxyribonuclease V, gamma subunit AAA_19 PF13245.6 EMT50395.1 - 0.024 15.0 0.1 0.16 12.3 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EMT50396.1 - 2.2e-21 77.3 13.2 2.2e-21 77.3 13.2 7.7 2 2 3 5 5 1 1 AAA domain SbcCD_C PF13558.6 EMT50396.1 - 3.6e-13 49.5 0.1 1.1e-12 47.9 0.1 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EMT50396.1 - 3.3e-12 46.3 0.9 4.1e-06 26.4 0.3 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMT50396.1 - 7.1e-07 28.9 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EMT50396.1 - 0.00059 19.7 4.2 0.00064 19.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EMT50396.1 - 0.014 15.9 0.0 0.014 15.9 0.0 6.4 5 3 0 6 6 6 0 ABC transporter DUF87 PF01935.17 EMT50396.1 - 0.28 11.2 0.0 0.28 11.2 0.0 6.8 5 2 1 6 6 4 0 Helicase HerA, central domain DUF1460 PF07313.12 EMT50396.1 - 0.31 10.4 4.1 0.1 12.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1460) AAA_22 PF13401.6 EMT50396.1 - 0.79 10.0 0.0 0.79 10.0 0.0 3.8 3 1 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EMT50396.1 - 1.1 8.9 0.0 1.1 8.9 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Bacillus_HBL PF05791.11 EMT50396.1 - 1.3 8.8 5.7 0.24 11.2 0.9 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Metallophos PF00149.28 EMT50397.1 - 1.6e-12 48.4 0.0 4e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SbcD_C PF12320.8 EMT50397.1 - 6e-10 39.3 2.0 9.1e-10 38.7 0.6 2.0 2 0 0 2 2 2 1 Type 5 capsule protein repressor C-terminal domain Metallophos_2 PF12850.7 EMT50397.1 - 2.4e-09 37.6 0.0 1.1e-07 32.2 0.0 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain baeRF_family2 PF18844.1 EMT50397.1 - 0.29 11.2 6.9 1.5 8.8 0.1 3.6 4 0 0 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 2 COX15-CtaA PF02628.15 EMT50399.1 - 3.5e-34 118.3 36.8 1.2e-25 90.2 27.6 4.0 1 1 1 2 2 2 2 Cytochrome oxidase assembly protein DUF2070 PF09843.9 EMT50399.1 - 0.16 10.2 12.6 0.29 9.4 2.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Fzo_mitofusin PF04799.13 EMT50399.1 - 0.43 10.1 1.6 0.9 9.1 1.6 1.6 1 0 0 1 1 1 0 fzo-like conserved region DUF1648 PF07853.11 EMT50399.1 - 0.55 9.9 0.0 0.55 9.9 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1648) FeoB_associated PF12669.7 EMT50399.1 - 3.3 8.2 10.3 0.48 10.9 0.6 3.5 4 0 0 4 4 4 0 FeoB-associated Cys-rich membrane protein Frag1 PF10277.9 EMT50399.1 - 6.2 6.3 21.5 0.25 10.8 4.6 2.6 3 0 0 3 3 3 0 Frag1/DRAM/Sfk1 family UbiA PF01040.18 EMT50400.1 - 1.4e-65 221.1 24.7 1.8e-65 220.8 24.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF373 PF04123.13 EMT50400.1 - 0.011 15.3 13.3 0.11 11.9 2.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF373) DUF1980 PF09323.10 EMT50400.1 - 0.065 13.1 1.1 0.2 11.6 1.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3040 PF11239.8 EMT50400.1 - 0.91 9.8 0.0 0.91 9.8 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) DUF420 PF04238.12 EMT50401.1 - 6.6e-40 136.5 7.1 7.7e-40 136.2 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF420) DUF2306 PF10067.9 EMT50401.1 - 0.00011 22.4 2.1 0.086 13.0 0.2 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2306) DUF3112 PF11309.8 EMT50401.1 - 0.00064 19.2 3.7 0.0076 15.7 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) DUF4064 PF13273.6 EMT50401.1 - 0.031 14.5 4.7 0.041 14.2 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DHHC PF01529.20 EMT50401.1 - 0.067 13.3 6.1 0.11 12.6 0.3 2.3 2 1 0 2 2 2 0 DHHC palmitoyltransferase DUF3149 PF11346.8 EMT50401.1 - 0.091 12.4 3.0 0.83 9.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) CbiM PF01891.16 EMT50401.1 - 0.1 12.4 6.2 0.042 13.7 2.3 2.1 1 1 1 2 2 2 0 Cobalt uptake substrate-specific transmembrane region DUF4149 PF13664.6 EMT50401.1 - 0.11 12.8 3.3 0.14 12.5 1.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DUF2569 PF10754.9 EMT50401.1 - 0.13 12.7 7.7 0.22 12.0 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF2663 PF10864.8 EMT50401.1 - 0.16 12.4 1.2 1.4 9.3 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Tetraspanin PF00335.20 EMT50401.1 - 0.19 11.4 5.5 0.24 11.1 5.5 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF4271 PF14093.6 EMT50401.1 - 0.22 11.4 10.6 0.8 9.6 10.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) NDUF_B4 PF07225.12 EMT50401.1 - 0.37 10.7 0.9 11 5.9 0.1 2.5 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DMT_YdcZ PF04657.13 EMT50401.1 - 1.2 9.5 12.1 0.85 9.9 1.8 2.2 2 0 0 2 2 2 0 Putative inner membrane exporter, YdcZ Wzy_C PF04932.15 EMT50401.1 - 3.6 7.2 12.2 85 2.7 12.2 2.5 1 1 0 1 1 1 0 O-Antigen ligase DUF373 PF04123.13 EMT50401.1 - 4.5 6.6 8.1 1.3 8.4 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Caa3_CtaG PF09678.10 EMT50402.1 - 5.4e-60 202.7 17.5 6.5e-60 202.5 17.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Chromate_transp PF02417.15 EMT50402.1 - 0.00082 19.5 16.0 0.0039 17.4 8.9 2.5 1 1 1 2 2 2 2 Chromate transporter DUF5643 PF18705.1 EMT50403.1 - 3.8e-15 55.9 5.1 5.5e-07 29.6 0.0 3.6 3 1 0 3 3 3 3 Family of unknown function (DUF5643) DUF4179 PF13786.6 EMT50403.1 - 6.8e-14 52.1 0.4 4.4e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4179) zf-HC2 PF13490.6 EMT50403.1 - 8.2e-07 29.2 0.8 2.3e-06 27.8 0.8 1.8 1 0 0 1 1 1 1 Putative zinc-finger Nsp1_C PF05064.13 EMT50403.1 - 0.11 12.3 0.4 0.21 11.4 0.4 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region Nha1_C PF08619.10 EMT50403.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Spore_SspJ PF09575.10 EMT50403.1 - 2.6 8.5 4.2 0.94 9.9 0.2 2.4 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) Sigma70_r2 PF04542.14 EMT50404.1 - 1.6e-20 72.6 0.6 3.9e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT50404.1 - 2.3e-11 43.2 1.0 5.7e-11 41.9 1.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT50404.1 - 1.4e-06 27.7 0.8 3.4e-06 26.5 0.1 2.1 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT50404.1 - 3.2e-06 27.2 0.5 5.2e-06 26.5 0.5 1.4 1 1 0 1 1 1 1 ECF sigma factor Phage_antitermQ PF06530.12 EMT50404.1 - 0.0013 18.6 0.6 0.089 12.7 0.1 2.2 2 0 0 2 2 2 1 Phage antitermination protein Q HTH_16 PF12645.7 EMT50404.1 - 0.0047 16.9 0.3 0.0089 16.1 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.19 EMT50404.1 - 0.0051 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Bap31_Bap29_C PF18035.1 EMT50404.1 - 0.02 14.9 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain HTH_AsnC-type PF13404.6 EMT50404.1 - 0.023 14.5 0.7 0.057 13.3 0.3 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HU-CCDC81_euk_2 PF18289.1 EMT50404.1 - 0.056 13.6 0.0 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 DUF1492 PF07374.11 EMT50404.1 - 0.072 13.3 0.7 0.25 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) Gag_p24 PF00607.20 EMT50404.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.6 1 1 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) COX4_pro PF03626.14 EMT50405.1 - 8.4e-12 45.3 17.5 1.1e-11 44.9 17.5 1.2 1 0 0 1 1 1 1 Prokaryotic Cytochrome C oxidase subunit IV PsbL PF02419.17 EMT50405.1 - 0.23 11.5 1.5 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 PsbL protein COX3 PF00510.18 EMT50406.1 - 2.9e-20 73.2 21.7 6e-20 72.2 21.7 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Jagunal PF07086.12 EMT50406.1 - 0.0064 16.6 1.5 0.0064 16.6 1.5 1.9 1 1 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis MARVEL PF01284.23 EMT50406.1 - 0.48 10.4 15.2 0.044 13.8 1.8 2.5 1 1 1 2 2 2 0 Membrane-associating domain COX1 PF00115.20 EMT50407.1 - 7.1e-154 512.8 72.0 7.1e-154 512.8 72.0 1.9 2 0 0 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I SpoIIIAC PF06686.11 EMT50407.1 - 0.43 10.8 11.6 0.81 9.9 0.6 4.2 4 0 0 4 4 4 0 Stage III sporulation protein AC/AD protein family COX2 PF00116.20 EMT50408.1 - 3.9e-25 88.1 0.2 1.2e-22 80.0 0.0 2.3 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain Cytochrom_C PF00034.21 EMT50408.1 - 2.5e-13 51.0 0.0 4.8e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c COX2_TM PF02790.15 EMT50408.1 - 7.9e-11 42.0 1.4 1.4e-10 41.1 1.4 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain Cytochrome_CBB3 PF13442.6 EMT50408.1 - 1.6e-08 34.7 0.0 2.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III RDD PF06271.12 EMT50408.1 - 0.0048 17.1 0.5 0.0079 16.4 0.5 1.3 1 0 0 1 1 1 1 RDD family Cytochrom_C550 PF14495.6 EMT50408.1 - 0.039 13.6 0.3 0.26 11.0 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c-550 domain AA_permease_2 PF13520.6 EMT50408.1 - 0.046 12.6 0.3 0.061 12.1 0.3 1.1 1 0 0 1 1 1 0 Amino acid permease MscS_TM PF12794.7 EMT50408.1 - 0.082 11.8 0.7 0.12 11.2 0.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 LPAM_2 PF13627.6 EMT50408.1 - 0.49 10.3 3.1 1.3 9.0 3.1 1.8 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site RIFIN PF02009.16 EMT50408.1 - 0.52 10.2 1.7 0.82 9.5 1.1 1.6 2 0 0 2 2 2 0 Rifin adh_short PF00106.25 EMT50409.1 - 2.8e-52 177.0 0.0 3.8e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMT50409.1 - 2e-38 132.3 0.0 2.5e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMT50409.1 - 1.4e-12 47.9 0.1 2e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMT50409.1 - 1.9e-08 34.0 0.0 2.6e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EMT50409.1 - 0.034 14.1 0.1 0.046 13.6 0.1 1.4 1 1 0 1 1 1 0 NAD(P)H-binding EmrE PF13536.6 EMT50410.1 - 1e-104 349.7 19.7 1.5e-104 349.2 19.7 1.2 1 0 0 1 1 1 1 Putative multidrug resistance efflux transporter DUF2512 PF10710.9 EMT50411.1 - 1.2e-08 34.7 5.1 1.3e-08 34.5 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2512) Phage_holin_4_2 PF04020.13 EMT50411.1 - 1 10.1 11.6 3.7 8.3 11.5 1.7 1 1 0 1 1 1 0 Mycobacterial 4 TMS phage holin, superfamily IV MFS_1 PF07690.16 EMT50412.1 - 8.6e-51 172.9 62.6 3.5e-50 170.9 59.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT50412.1 - 1.1e-15 57.4 35.4 2.9e-13 49.5 14.3 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EMT50412.1 - 6.3e-11 41.4 15.4 6.3e-11 41.4 15.4 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2583 PF10762.9 EMT50412.1 - 0.16 12.4 0.1 0.16 12.4 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2583) DUF983 PF06170.12 EMT50412.1 - 0.91 10.0 0.0 0.91 10.0 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF983) SurA_N_3 PF13624.6 EMT50413.1 - 5.4e-14 52.3 2.6 8.1e-12 45.2 0.4 2.7 2 1 1 3 3 3 2 SurA N-terminal domain SurA_N PF09312.11 EMT50413.1 - 0.00011 22.3 0.4 0.00032 20.8 0.2 1.8 2 0 0 2 2 2 1 SurA N-terminal domain SurA_N_2 PF13623.6 EMT50413.1 - 0.001 18.9 3.9 0.0017 18.2 1.6 2.3 1 1 2 3 3 3 1 SurA N-terminal domain Rotamase_2 PF13145.6 EMT50413.1 - 0.0023 18.7 0.4 0.0023 18.7 0.4 3.0 2 1 1 3 3 3 1 PPIC-type PPIASE domain DnaG_DnaB_bind PF08278.11 EMT50413.1 - 0.0033 18.0 1.0 0.022 15.4 0.1 2.1 2 0 0 2 2 2 1 DNA primase DnaG DnaB-binding Trans_reg_C PF00486.28 EMT50413.1 - 0.097 12.8 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Trigger_C PF05698.14 EMT50413.1 - 0.18 11.8 11.1 0.034 14.1 1.6 3.0 1 1 2 3 3 3 0 Bacterial trigger factor protein (TF) C-terminus PetM PF08041.11 EMT50413.1 - 0.57 9.8 6.7 0.86 9.2 6.7 1.2 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 XhlA PF10779.9 EMT50414.1 - 3.6e-06 27.1 1.2 3.6e-06 27.1 1.2 2.0 1 1 0 2 2 2 1 Haemolysin XhlA Cep57_CLD PF14073.6 EMT50414.1 - 0.0033 17.5 7.8 0.0033 17.5 7.8 1.5 2 0 0 2 2 2 1 Centrosome localisation domain of Cep57 Spc7 PF08317.11 EMT50414.1 - 0.0091 14.9 12.0 0.01 14.7 12.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF812 PF05667.11 EMT50414.1 - 0.014 14.3 14.2 0.018 14.0 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TMPIT PF07851.13 EMT50414.1 - 0.032 13.5 4.2 0.04 13.2 4.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein Ubiquitin_2 PF14560.6 EMT50414.1 - 0.04 14.4 1.3 0.075 13.5 1.3 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF3323 PF11796.8 EMT50414.1 - 0.17 11.7 1.6 0.21 11.5 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) FlaC_arch PF05377.11 EMT50414.1 - 0.23 11.9 4.4 0.11 12.9 1.4 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CR6_interact PF10147.9 EMT50414.1 - 0.25 11.0 11.1 0.072 12.8 4.5 2.0 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 COG2 PF06148.11 EMT50414.1 - 0.27 11.3 5.6 0.31 11.1 4.6 1.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MerR-DNA-bind PF09278.11 EMT50414.1 - 0.53 10.8 6.2 2.6 8.6 0.7 2.6 1 1 1 2 2 2 0 MerR, DNA binding AAA_11 PF13086.6 EMT50414.1 - 0.56 9.9 5.4 0.48 10.2 4.4 1.3 1 1 0 1 1 1 0 AAA domain EF-G-binding_N PF07299.11 EMT50414.1 - 0.67 10.5 6.0 0.84 10.2 0.8 2.4 1 1 1 2 2 2 0 Elongation factor G-binding protein, N-terminal SlyX PF04102.12 EMT50414.1 - 0.94 10.1 8.1 1.1 10.0 6.5 2.1 1 1 0 1 1 1 0 SlyX DUF724 PF05266.14 EMT50414.1 - 0.99 9.2 10.3 1.8 8.3 10.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Exonuc_VII_L PF02601.15 EMT50414.1 - 1 8.8 5.9 1.3 8.6 5.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Snapin_Pallidin PF14712.6 EMT50414.1 - 1.1 9.7 11.0 8.2 6.9 5.4 2.3 2 1 0 2 2 2 0 Snapin/Pallidin DUF16 PF01519.16 EMT50414.1 - 1.5 9.3 10.2 12 6.4 10.2 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1366 PF07104.11 EMT50414.1 - 1.6 8.4 6.3 2.2 8.0 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1366) DUF4795 PF16043.5 EMT50414.1 - 1.8 8.1 11.8 2.6 7.6 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Fungal_TACC PF12709.7 EMT50414.1 - 3 8.3 13.7 0.49 10.9 5.3 2.8 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins CorA PF01544.18 EMT50414.1 - 3.8 6.7 7.8 9.3 5.5 7.8 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein YabA PF06156.13 EMT50414.1 - 3.9 8.2 6.7 4.7 7.9 6.3 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DUF3498 PF12004.8 EMT50414.1 - 7.5 5.6 9.6 8.6 5.4 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Patatin PF01734.22 EMT50415.1 - 7.4e-19 68.7 0.6 1.4e-17 64.5 0.2 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase DegV PF02645.16 EMT50416.1 - 2.8e-79 266.4 0.2 3.2e-79 266.2 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 Dak1_2 PF13684.6 EMT50416.1 - 9.1e-05 21.7 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Dihydroxyacetone kinase family Methyltransf_11 PF08241.12 EMT50417.1 - 1.8e-08 34.9 0.0 3.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT50417.1 - 9.3e-07 29.5 0.0 1.8e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT50417.1 - 0.00095 19.0 0.0 0.0017 18.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EMT50417.1 - 0.0045 16.6 0.0 0.0075 15.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 EMT50417.1 - 0.031 14.1 0.0 0.044 13.6 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain VWA PF00092.28 EMT50418.1 - 1.6e-31 109.9 0.2 2.9e-22 79.8 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 EMT50418.1 - 1.5e-28 99.5 0.2 6.6e-17 62.1 0.0 2.7 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 EMT50418.1 - 4.5e-15 55.9 0.1 3e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain GATase1_like PF07090.11 EMT50418.1 - 6.8e-12 45.3 2.3 1.5e-07 31.1 0.5 2.9 2 1 0 2 2 2 2 Putative glutamine amidotransferase VWA_CoxE PF05762.14 EMT50418.1 - 4e-06 26.4 0.3 0.0013 18.2 0.0 3.2 2 2 0 2 2 2 2 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 EMT50418.1 - 0.0003 21.0 0.1 0.00065 19.9 0.1 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus FixH PF05751.11 EMT50418.1 - 0.072 13.1 0.2 0.49 10.4 0.1 2.4 2 0 0 2 2 2 0 FixH BatA PF07584.11 EMT50419.1 - 5.8e-18 65.0 11.3 5.8e-18 65.0 11.3 2.1 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal VWA_2 PF13519.6 EMT50419.1 - 3.2e-14 53.5 0.0 6.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EMT50419.1 - 8.6e-05 22.8 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF58 PF01882.18 EMT50420.1 - 3.6e-21 75.2 0.1 9.8e-20 70.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function DUF58 VWA_2 PF13519.6 EMT50420.1 - 0.028 15.1 0.0 0.066 13.9 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain AAA_3 PF07726.11 EMT50421.1 - 1.2e-63 212.9 0.2 1.8e-63 212.2 0.2 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMT50421.1 - 1e-14 54.7 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EMT50421.1 - 2.2e-12 46.6 0.4 5.4e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 EMT50421.1 - 2.6e-07 31.1 0.0 5.6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 EMT50421.1 - 5.9e-05 22.3 0.0 0.00011 21.4 0.0 1.4 1 1 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 EMT50421.1 - 0.00067 19.4 0.0 0.0091 15.7 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 EMT50421.1 - 0.0012 18.6 0.0 0.019 14.7 0.0 2.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EMT50421.1 - 0.0032 17.9 0.1 0.0093 16.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EMT50421.1 - 0.008 15.6 0.1 0.021 14.2 0.0 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EMT50421.1 - 0.018 15.3 0.0 0.072 13.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EMT50421.1 - 0.018 15.2 0.0 0.056 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) FtsK_SpoIIIE PF01580.18 EMT50421.1 - 0.033 13.5 0.0 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF4131 PF13567.6 EMT50422.1 - 0.086 12.5 4.1 0.1 12.2 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_S64 PF08192.11 EMT50422.1 - 5.3 5.4 14.9 7.2 5.0 14.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 ABC2_membrane_2 PF12679.7 EMT50423.1 - 1.8e-12 47.2 18.0 5e-12 45.7 18.0 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 EMT50423.1 - 1.3e-07 31.0 22.1 1.3e-07 31.0 22.1 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 EMT50423.1 - 6.4e-05 23.0 21.0 7e-05 22.9 15.1 2.3 2 1 0 2 2 2 1 ABC-2 family transporter protein Stevor PF17410.2 EMT50423.1 - 0.0097 15.5 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF2474 PF10617.9 EMT50423.1 - 0.74 9.7 6.4 0.25 11.2 0.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) ABC_tran PF00005.27 EMT50424.1 - 4.2e-30 105.0 0.0 3.9e-28 98.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EMT50424.1 - 2.1e-11 44.2 1.6 7.7e-08 32.5 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EMT50424.1 - 2.8e-08 34.4 0.6 6.5e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 EMT50424.1 - 7.4e-05 22.6 0.0 0.055 13.2 0.0 2.1 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EMT50424.1 - 0.00048 19.6 0.1 0.19 11.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT50424.1 - 0.00075 19.8 0.2 0.0052 17.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT50424.1 - 0.0014 18.3 0.2 0.0034 17.1 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT50424.1 - 0.015 15.8 0.1 0.032 14.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EMT50424.1 - 0.027 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMT50424.1 - 0.028 14.1 0.6 0.2 11.3 0.1 2.4 3 0 0 3 3 3 0 AAA domain MukB PF04310.12 EMT50424.1 - 0.029 14.2 0.2 0.41 10.4 0.1 2.1 2 0 0 2 2 2 0 MukB N-terminal Rad17 PF03215.15 EMT50424.1 - 0.065 13.2 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 EMT50424.1 - 0.13 11.8 0.2 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 EMT50424.1 - 0.2 12.1 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF308 PF03729.13 EMT50425.1 - 0.046 14.1 2.6 0.15 12.4 1.9 2.1 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF4350 PF14258.6 EMT50425.1 - 0.075 13.5 0.1 0.2 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) CARDB PF07705.11 EMT50425.1 - 0.08 13.2 2.3 0.7 10.2 0.7 2.5 2 0 0 2 2 2 0 CARDB Glyco_hydro_42M PF08532.10 EMT50425.1 - 0.082 12.4 0.5 0.21 11.1 0.1 1.8 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain DUF4115 PF13464.6 EMT50425.1 - 0.085 13.1 2.3 0.49 10.6 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4115) MOSC PF03473.17 EMT50426.1 - 3.5e-22 78.8 0.0 6e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EMT50426.1 - 1.6e-09 37.7 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF3316 PF11777.8 EMT50427.1 - 0.029 14.5 1.6 0.051 13.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) ABM PF03992.16 EMT50430.1 - 1e-20 73.6 0.2 1.3e-20 73.3 0.2 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Nitroreductase PF00881.24 EMT50431.1 - 2.9e-31 108.8 0.0 4e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EMT50431.1 - 9.4e-11 41.7 0.0 3.5e-05 23.5 0.1 2.2 1 1 0 2 2 2 2 Putative TM nitroreductase MarR PF01047.22 EMT50432.1 - 6.1e-16 58.1 0.6 5.1e-15 55.2 0.1 2.2 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EMT50432.1 - 6.2e-14 51.6 0.5 9.9e-13 47.8 0.2 2.2 2 0 0 2 2 2 1 MarR family HTH_34 PF13601.6 EMT50432.1 - 4.5e-11 42.8 0.1 6.6e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EMT50432.1 - 8.5e-08 31.6 0.0 1.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EMT50432.1 - 1.8e-06 27.9 1.1 2.8e-06 27.3 0.2 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 EMT50432.1 - 2.7e-06 27.2 0.4 6e-06 26.1 0.4 1.6 1 0 0 1 1 1 1 HTH domain HTH_27 PF13463.6 EMT50432.1 - 4.3e-06 27.1 0.1 1.7e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain HxlR PF01638.17 EMT50432.1 - 0.00027 20.7 0.2 0.00068 19.4 0.1 1.8 1 1 0 1 1 1 1 HxlR-like helix-turn-helix HTH_5 PF01022.20 EMT50432.1 - 0.00056 19.7 0.2 0.0014 18.5 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family Mga PF05043.13 EMT50432.1 - 0.0044 17.6 0.6 0.011 16.4 0.1 1.9 2 0 0 2 2 2 1 Mga helix-turn-helix domain PadR PF03551.14 EMT50432.1 - 0.0062 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family RTP PF02334.16 EMT50432.1 - 0.0072 16.9 0.0 0.015 15.9 0.0 1.7 1 1 0 1 1 1 1 Replication terminator protein HTH_12 PF08461.10 EMT50432.1 - 0.0094 15.9 0.2 0.018 15.0 0.2 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain DUF1323 PF07037.11 EMT50432.1 - 0.016 15.6 1.1 0.025 15.0 0.6 1.6 1 1 0 1 1 1 0 Putative transcription regulator (DUF1323) TFIIE_alpha PF02002.17 EMT50432.1 - 0.025 14.4 0.2 0.052 13.4 0.1 1.7 1 1 1 2 2 2 0 TFIIE alpha subunit FUR PF01475.19 EMT50432.1 - 0.048 13.8 0.1 0.092 12.9 0.0 1.5 1 1 0 1 1 1 0 Ferric uptake regulator family HTH_28 PF13518.6 EMT50432.1 - 0.071 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain GntR PF00392.21 EMT50432.1 - 0.084 12.5 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family B-block_TFIIIC PF04182.12 EMT50432.1 - 0.099 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_1 PF00126.27 EMT50432.1 - 0.3 11.1 6.5 0.061 13.3 1.5 2.4 2 1 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Nitroreductase PF00881.24 EMT50434.1 - 3.8e-28 98.7 0.0 5.5e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EMT50434.1 - 2.8e-05 23.8 0.0 0.082 12.5 0.0 2.6 2 1 0 2 2 2 2 Putative TM nitroreductase UBA_3 PF09288.10 EMT50434.1 - 0.12 12.3 0.0 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain HxlR PF01638.17 EMT50435.1 - 7.2e-40 134.7 0.1 9.2e-40 134.4 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 EMT50435.1 - 0.0078 16.2 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_12 PF08461.10 EMT50435.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_34 PF13601.6 EMT50435.1 - 0.18 12.0 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain DJ-1_PfpI PF01965.24 EMT50436.1 - 6.5e-32 110.6 0.0 7.5e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Glyoxalase PF00903.25 EMT50437.1 - 7.6e-14 52.0 0.0 8.7e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMT50437.1 - 0.0015 18.7 0.0 0.0022 18.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EMT50437.1 - 0.0017 19.1 0.0 0.0026 18.5 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EMT50437.1 - 0.0045 17.2 0.0 0.0057 16.8 0.0 1.2 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EMT50437.1 - 0.017 15.2 0.0 0.24 11.5 0.0 2.1 1 1 0 1 1 1 0 Glyoxalase-like domain HTH_24 PF13412.6 EMT50438.1 - 7e-13 47.9 0.1 1.4e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EMT50438.1 - 1.6e-12 47.1 0.0 2.3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 EMT50438.1 - 5.9e-10 39.0 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain MarR PF01047.22 EMT50438.1 - 4.7e-05 23.2 0.3 8.3e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 EMT50438.1 - 0.00013 21.9 0.1 0.00027 20.8 0.1 1.5 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 EMT50438.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 MarR family Lactamase_B_2 PF12706.7 EMT50439.1 - 8.4e-10 38.5 0.1 2.1e-09 37.2 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMT50439.1 - 1.5e-09 38.0 0.2 2.1e-09 37.5 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMT50439.1 - 8.8e-06 25.9 0.2 2.5e-05 24.4 0.2 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF4417 PF14386.6 EMT50439.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4417) tRNA_U5-meth_tr PF05958.11 EMT50440.1 - 1.9e-26 92.9 0.0 1.9e-24 86.4 0.0 2.8 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 EMT50440.1 - 4e-12 46.0 0.4 9.8e-12 44.7 0.4 1.7 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.6 EMT50440.1 - 6.9e-11 42.2 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT50440.1 - 7.5e-08 33.0 0.0 2.5e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EMT50440.1 - 8.2e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EMT50440.1 - 1.5e-05 25.6 0.0 5.1e-05 23.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 EMT50440.1 - 4.6e-05 23.0 0.0 0.00012 21.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EMT50440.1 - 0.00023 20.8 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EMT50440.1 - 0.0043 16.8 0.6 0.26 11.0 0.6 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 EMT50440.1 - 0.0049 16.3 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EMT50440.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 EMT50440.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 EMT50440.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EMT50440.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.12 EMT50440.1 - 0.043 14.5 0.0 0.14 12.9 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain NodS PF05401.11 EMT50440.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 EMT50440.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Sigma70_r2 PF04542.14 EMT50441.1 - 7.8e-20 70.4 0.4 1.5e-19 69.5 0.4 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT50441.1 - 5.9e-15 54.7 2.0 1.2e-14 53.7 0.7 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT50441.1 - 2.7e-11 42.8 0.9 2.7e-11 42.8 0.9 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_16 PF12645.7 EMT50441.1 - 4.4e-05 23.5 0.2 8.3e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 EMT50441.1 - 0.00012 22.0 1.5 0.00098 19.1 1.5 2.0 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 EMT50441.1 - 0.00024 20.8 0.9 0.00042 20.0 0.2 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 EMT50441.1 - 0.02 14.4 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EMT50441.1 - 0.021 14.6 0.1 0.067 13.0 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Phage_antitermQ PF06530.12 EMT50441.1 - 0.031 14.2 0.5 0.14 12.0 0.1 2.0 2 1 0 2 2 2 0 Phage antitermination protein Q GerE PF00196.19 EMT50441.1 - 0.047 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_17 PF12728.7 EMT50441.1 - 0.1 12.8 0.4 1.4 9.2 0.1 2.8 3 1 0 3 3 3 0 Helix-turn-helix domain DUF4179 PF13786.6 EMT50442.1 - 6.6e-19 68.2 3.2 1.3e-18 67.2 1.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4179) DUF5643 PF18705.1 EMT50442.1 - 3.3e-16 59.3 8.3 2.7e-06 27.3 0.1 5.2 2 1 0 3 3 3 3 Family of unknown function (DUF5643) zf-HC2 PF13490.6 EMT50442.1 - 0.0018 18.5 0.5 0.0035 17.6 0.5 1.5 1 0 0 1 1 1 1 Putative zinc-finger Annexin_like PF18411.1 EMT50442.1 - 0.095 13.0 0.5 0.89 9.8 0.0 2.9 4 1 1 5 5 5 0 Annexin-like domain DUF2604 PF10790.9 EMT50442.1 - 0.12 12.7 2.2 14 6.1 0.0 3.3 3 0 0 3 3 3 0 Protein of Unknown function (DUF2604) Sigma70_r2 PF04542.14 EMT50443.1 - 4.2e-17 61.7 0.6 7.5e-17 60.9 0.6 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT50443.1 - 2e-15 56.2 1.7 2e-15 56.2 1.7 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT50443.1 - 9.8e-10 37.8 0.8 9.8e-10 37.8 0.8 2.2 2 1 1 3 3 3 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT50443.1 - 2.5e-05 24.3 2.3 3.1e-05 24.0 2.3 1.2 1 0 0 1 1 1 1 ECF sigma factor DUF1492 PF07374.11 EMT50443.1 - 0.0018 18.4 0.9 0.0034 17.5 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1492) HTH_AsnC-type PF13404.6 EMT50443.1 - 0.0098 15.7 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain GerE PF00196.19 EMT50443.1 - 0.014 14.9 0.2 0.037 13.6 0.1 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 EMT50443.1 - 0.016 15.0 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Mga PF08280.11 EMT50443.1 - 0.034 14.2 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain DUF1495 PF07381.11 EMT50443.1 - 0.071 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) DUF4179 PF13786.6 EMT50444.1 - 3.6e-19 69.0 1.2 3.6e-19 69.0 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4179) DUF5643 PF18705.1 EMT50444.1 - 1.4e-14 54.0 16.4 1.7e-07 31.2 0.6 4.8 2 1 1 3 3 3 3 Family of unknown function (DUF5643) zf-HC2 PF13490.6 EMT50444.1 - 0.00036 20.7 0.1 0.00086 19.5 0.1 1.6 1 0 0 1 1 1 1 Putative zinc-finger DUF4710 PF15828.5 EMT50445.1 - 0.03 14.4 0.3 0.058 13.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) PALP PF00291.25 EMT50446.1 - 1.7e-80 270.6 0.2 2e-80 270.4 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EMT50446.1 - 4.5e-29 100.1 0.0 7.6e-29 99.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal regulatory domain of Threonine dehydratase YhfH PF14149.6 EMT50447.1 - 1.8e-15 56.6 5.0 2.9e-15 56.0 5.0 1.3 1 0 0 1 1 1 1 YhfH-like protein DZR PF12773.7 EMT50447.1 - 0.0022 18.0 4.0 0.0026 17.7 4.0 1.1 1 0 0 1 1 1 1 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 EMT50447.1 - 0.003 17.4 1.7 0.0035 17.2 1.7 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Ribosomal_L37ae PF01780.19 EMT50447.1 - 0.011 15.9 2.2 0.011 15.8 2.2 1.1 1 0 0 1 1 1 0 Ribosomal L37ae protein family NOB1_Zn_bind PF08772.11 EMT50447.1 - 0.41 10.8 0.2 0.41 10.8 0.2 2.0 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like C1_2 PF03107.16 EMT50447.1 - 0.92 9.9 7.6 1.9 8.9 0.5 2.1 1 1 1 2 2 2 0 C1 domain Peptidase_M29 PF02073.15 EMT50449.1 - 9.4e-179 594.4 0.0 1.1e-178 594.2 0.0 1.0 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) DUF1471 PF07338.13 EMT50449.1 - 0.13 12.2 0.1 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) BioY PF02632.14 EMT50451.1 - 5.1e-36 123.7 18.1 7.6e-36 123.2 18.1 1.2 1 0 0 1 1 1 1 BioY family p450 PF00067.22 EMT50452.1 - 2.6e-96 323.2 0.0 2.9e-96 323.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HATPase_c PF02518.26 EMT50453.1 - 6.1e-29 100.8 0.2 2e-28 99.1 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 EMT50453.1 - 1.1e-10 41.7 0.0 8.4e-09 35.7 0.0 2.6 3 0 0 3 3 3 1 HAMP domain HisKA PF00512.25 EMT50453.1 - 2.8e-10 40.1 0.0 1e-09 38.3 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 EMT50453.1 - 8.6e-06 25.6 0.1 1.9e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 EMT50453.1 - 0.0039 17.0 0.0 0.0091 15.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TetR_C_2 PF08361.11 EMT50453.1 - 0.004 17.2 0.1 0.011 15.9 0.1 1.7 1 0 0 1 1 1 1 MAATS-type transcriptional repressor, C-terminal region HATPase_c_2 PF13581.6 EMT50453.1 - 0.042 13.8 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain BLOC1_2 PF10046.9 EMT50453.1 - 0.047 14.0 1.1 0.11 12.8 1.1 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Takusan PF04822.13 EMT50453.1 - 0.048 13.5 0.8 0.18 11.7 0.8 2.0 1 0 0 1 1 1 0 Takusan MCPsignal PF00015.21 EMT50453.1 - 0.096 12.5 0.0 1.2 9.0 0.2 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain MutS_III PF05192.18 EMT50453.1 - 0.97 9.6 3.6 1.2 9.3 2.5 1.8 1 1 1 2 2 2 0 MutS domain III Response_reg PF00072.24 EMT50454.1 - 2.4e-31 108.2 0.1 3.6e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT50454.1 - 1.2e-25 89.4 1.1 2.1e-25 88.6 0.1 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal GerE PF00196.19 EMT50454.1 - 0.083 12.4 0.3 0.45 10.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Glyco_hydro_20b PF02838.15 EMT50454.1 - 0.11 13.3 0.0 1.9 9.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, domain 2 NLPC_P60 PF00877.19 EMT50455.1 - 3.6e-29 100.9 0.1 6.2e-29 100.1 0.1 1.4 1 0 0 1 1 1 1 NlpC/P60 family CHAP PF05257.16 EMT50455.1 - 0.0003 21.3 0.0 0.00069 20.1 0.0 1.5 1 0 0 1 1 1 1 CHAP domain DUF1175 PF06672.11 EMT50455.1 - 0.018 14.7 1.8 0.17 11.5 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1175) Amidase_6 PF12671.7 EMT50455.1 - 0.029 14.5 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative amidase domain LRAT PF04970.13 EMT50455.1 - 0.032 14.5 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF1287 PF06940.11 EMT50455.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) DUF4059 PF13268.6 EMT50456.1 - 0.01 16.3 0.1 0.021 15.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4059) PspA_IM30 PF04012.12 EMT50457.1 - 5.8e-48 163.4 28.2 7e-48 163.1 28.2 1.0 1 0 0 1 1 1 1 PspA/IM30 family FTHFS PF01268.19 EMT50457.1 - 0.0025 16.1 2.7 0.0038 15.5 2.7 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase VSG_B PF13206.6 EMT50457.1 - 0.0031 16.8 7.6 0.0039 16.5 7.6 1.2 1 0 0 1 1 1 1 Trypanosomal VSG domain O-FucT PF10250.9 EMT50457.1 - 0.0061 16.3 1.3 0.008 15.9 1.3 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Tup_N PF08581.10 EMT50457.1 - 1.2 9.5 14.6 0.31 11.3 2.2 3.3 3 1 0 3 3 3 0 Tup N-terminal RrnaAD PF00398.20 EMT50458.1 - 9.4e-06 24.9 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EMT50458.1 - 0.0015 19.2 0.0 0.0023 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT50458.1 - 0.0045 17.7 0.0 0.0083 16.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMT50458.1 - 0.0069 16.0 0.0 0.012 15.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_28 PF02636.17 EMT50458.1 - 0.01 15.5 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 EMT50458.1 - 0.026 14.3 0.0 5.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EMT50458.1 - 0.029 15.0 0.0 0.053 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EMT50458.1 - 0.07 13.0 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EMT50458.1 - 0.22 10.8 0.0 2.6 7.3 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain DUF2154 PF09922.9 EMT50459.1 - 6.4e-33 113.0 0.4 8.7e-33 112.6 0.4 1.2 1 0 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF HisKA_3 PF07730.13 EMT50460.1 - 1.4e-19 70.3 9.1 1.4e-19 70.3 9.1 2.3 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 EMT50460.1 - 4.6e-09 36.8 0.1 2.1e-08 34.6 0.1 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 EMT50460.1 - 4.9e-05 23.6 0.0 0.0003 21.1 0.0 2.5 2 0 0 2 2 2 1 HAMP domain HATPase_c_2 PF13581.6 EMT50460.1 - 0.018 15.0 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF4310 PF14187.6 EMT50460.1 - 0.021 14.5 0.5 0.049 13.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4310) Raco_middle PF17651.1 EMT50460.1 - 0.036 13.7 0.4 0.072 12.8 0.2 1.6 2 0 0 2 2 2 0 RACo middle region ERM PF00769.19 EMT50460.1 - 0.068 13.0 10.6 0.085 12.7 10.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UPF0242 PF06785.11 EMT50460.1 - 0.16 12.1 10.0 0.031 14.4 4.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HATPase_c_3 PF13589.6 EMT50460.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Bestrophin PF01062.21 EMT50460.1 - 0.19 11.1 1.6 0.33 10.3 1.6 1.5 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF1664 PF07889.12 EMT50460.1 - 0.23 11.5 2.1 3.4 7.7 0.7 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) OSCP PF00213.18 EMT50460.1 - 0.43 10.7 7.3 0.74 9.9 7.3 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit YueH PF14166.6 EMT50460.1 - 2.2 8.2 8.2 3.9 7.4 0.1 2.9 2 1 1 3 3 3 0 YueH-like protein Response_reg PF00072.24 EMT50461.1 - 4.2e-25 88.1 0.1 6.7e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EMT50461.1 - 2e-21 75.3 0.1 3.7e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EMT50461.1 - 2.8e-06 26.9 0.5 5.7e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT50461.1 - 0.0003 20.2 0.1 0.00064 19.2 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 EMT50461.1 - 0.028 14.9 0.4 0.18 12.3 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain CENP-B_N PF04218.13 EMT50461.1 - 0.034 13.8 0.1 0.082 12.5 0.1 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF2089 PF09862.9 EMT50461.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Metallophos PF00149.28 EMT50462.1 - 5.3e-07 30.3 0.0 8.6e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Amidase_3 PF01520.18 EMT50464.1 - 1.3e-21 77.5 0.0 1.6e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase UPF0154 PF03672.13 EMT50465.1 - 6.8e-19 67.7 3.9 8.2e-19 67.4 3.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0154) EMC3_TMCO1 PF01956.16 EMT50465.1 - 0.005 16.6 0.3 0.0056 16.4 0.3 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like LapA_dom PF06305.11 EMT50465.1 - 0.11 12.3 0.3 0.29 11.0 0.3 1.7 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3188 PF11384.8 EMT50466.1 - 0.0009 18.9 1.8 0.002 17.8 1.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3188) TauE PF01925.19 EMT50467.1 - 2.1e-40 138.8 38.0 2.6e-40 138.6 38.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF3482 PF11981.8 EMT50467.1 - 0.6 9.5 1.4 0.97 8.8 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Sod_Fe_C PF02777.18 EMT50468.1 - 1.2e-43 147.5 0.0 2e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EMT50468.1 - 4.7e-32 110.3 3.0 7.5e-32 109.7 3.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF3221 PF11518.8 EMT50469.1 - 2.9e-07 30.7 0.0 4.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3221) LigB PF02900.18 EMT50470.1 - 4.3e-46 157.2 0.0 5e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Phage_tail_S PF05069.13 EMT50470.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Phage virion morphogenesis family CMD PF02627.20 EMT50471.1 - 2.7e-23 81.8 0.9 4.1e-23 81.2 0.9 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family CRS1_YhbY PF01985.21 EMT50471.1 - 0.036 14.2 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain CmcI PF04989.12 EMT50471.1 - 0.1 12.3 0.0 3 7.5 0.0 2.0 1 1 0 2 2 2 0 Cephalosporin hydroxylase Pyridox_ox_2 PF12900.7 EMT50472.1 - 8.2e-29 100.4 0.0 9.8e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EMT50472.1 - 3.4e-09 36.8 0.0 5.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EMT50472.1 - 0.0043 16.7 0.0 0.03 13.9 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like FMN_bind_2 PF04299.12 EMT50472.1 - 0.014 15.2 0.0 0.06 13.1 0.0 1.8 1 1 0 1 1 1 0 Putative FMN-binding domain Protoglobin PF11563.8 EMT50472.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.4 2 0 0 2 2 2 0 Protoglobin YdjM PF04307.14 EMT50473.1 - 1.5e-24 86.3 15.5 1.8e-24 86.0 15.0 1.3 1 1 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase MFS_3 PF05977.13 EMT50474.1 - 1.5e-06 27.0 0.0 1.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector NUDIX_4 PF14815.6 EMT50475.1 - 1.7e-27 95.6 0.1 3.5e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 EMT50475.1 - 8.2e-23 80.9 0.0 1.3e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EMT50475.1 - 1e-09 37.8 0.3 2.6e-09 36.5 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EMT50475.1 - 0.0012 19.1 4.2 0.0021 18.3 4.2 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 EMT50475.1 - 0.0066 17.0 0.0 1.9 9.1 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain KorB_C PF06613.11 EMT50475.1 - 0.047 13.7 0.1 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain PG_binding_2 PF08823.11 EMT50475.1 - 0.15 12.4 0.0 0.56 10.6 0.0 1.9 2 0 0 2 2 2 0 Putative peptidoglycan binding domain HHH_2 PF12826.7 EMT50475.1 - 0.17 12.0 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Bac_small_YrzI PF09501.10 EMT50476.1 - 2.5e-06 27.5 0.5 3.1e-06 27.2 0.5 1.1 1 0 0 1 1 1 1 Probable sporulation protein (Bac_small_yrzI) MCPsignal PF00015.21 EMT50477.1 - 2.7e-45 154.3 27.9 2.7e-45 154.3 27.9 4.1 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 EMT50477.1 - 5.2e-30 105.1 0.0 5.2e-30 105.1 0.0 3.9 3 1 0 3 3 3 1 Cache domain HAMP PF00672.25 EMT50477.1 - 9e-15 54.8 0.2 9e-15 54.8 0.2 5.2 7 1 0 7 7 6 1 HAMP domain Cache_3-Cache_2 PF17201.4 EMT50477.1 - 8.1e-08 31.9 0.0 8.1e-08 31.9 0.0 3.8 3 2 1 4 4 4 1 Cache 3/Cache 2 fusion domain dCache_2 PF08269.11 EMT50477.1 - 0.089 12.0 0.0 0.089 12.0 0.0 4.6 3 1 1 5 5 5 0 Cache domain sCache_2 PF17200.4 EMT50477.1 - 0.41 10.5 0.0 0.41 10.5 0.0 3.4 4 0 0 4 4 4 0 Single Cache domain 2 Syntaxin_2 PF14523.6 EMT50477.1 - 0.87 10.0 25.1 0.24 11.8 0.9 4.7 2 1 2 4 4 4 0 Syntaxin-like protein ApoLp-III PF07464.11 EMT50477.1 - 0.92 9.6 35.9 1.1 9.3 0.8 4.3 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) BLOC1_2 PF10046.9 EMT50477.1 - 2.9 8.3 27.5 2.1 8.7 0.9 5.6 3 2 4 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EMT50477.1 - 4.7 7.3 31.3 0.61 10.1 3.6 5.3 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EMT50477.1 - 9.3 6.6 35.0 0.59 10.4 2.9 6.2 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) HTH_27 PF13463.6 EMT50478.1 - 0.013 16.0 0.0 0.015 15.8 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain adh_short_C2 PF13561.6 EMT50479.1 - 3.5e-70 236.2 0.6 4.2e-70 236.0 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT50479.1 - 1.4e-47 161.7 0.2 1.7e-47 161.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT50479.1 - 1.1e-12 48.2 0.1 1.9e-12 47.5 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMT50479.1 - 2.3e-05 24.0 0.1 4.5e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMT50479.1 - 0.00028 20.8 3.2 0.00045 20.2 0.4 2.2 1 1 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMT50479.1 - 0.00042 19.8 0.0 0.00069 19.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EMT50479.1 - 0.0015 18.2 0.2 0.016 14.8 0.3 2.2 1 1 1 2 2 2 1 NmrA-like family Aminotran_5 PF00266.19 EMT50479.1 - 0.015 14.3 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Polysacc_synt_2 PF02719.15 EMT50479.1 - 0.036 13.2 0.1 0.056 12.6 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 EMT50479.1 - 0.077 13.6 0.6 0.18 12.4 0.2 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Acetyltransf_1 PF00583.25 EMT50480.1 - 1.8e-16 60.4 0.1 2.2e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT50480.1 - 7.4e-16 58.2 0.0 8.8e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT50480.1 - 1.3e-12 47.9 0.1 1.8e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT50480.1 - 3.7e-07 30.0 0.1 5.2e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 EMT50480.1 - 5.9e-07 29.7 0.0 7.3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT50480.1 - 5.6e-05 23.3 0.0 8.3e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT50480.1 - 0.00013 22.0 0.2 0.0029 17.7 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT50480.1 - 0.0057 16.8 0.1 0.0091 16.1 0.1 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EMT50480.1 - 0.03 15.0 0.0 0.041 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CBS PF00571.28 EMT50480.1 - 0.053 14.0 0.2 16 6.1 0.0 2.2 2 0 0 2 2 2 0 CBS domain DUF402 PF04167.13 EMT50481.1 - 1.7e-16 60.2 0.1 3.4e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF402) ABC_membrane PF00664.23 EMT50482.1 - 7.2e-50 170.2 6.6 9.3e-50 169.8 6.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMT50482.1 - 1.1e-30 106.9 0.0 1.9e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT50482.1 - 1.3e-06 28.0 2.0 4.4e-05 23.0 2.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMT50482.1 - 0.032 14.1 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EMT50482.1 - 0.052 13.9 0.4 0.25 11.7 0.2 2.3 2 1 0 2 2 2 0 AAA ATPase domain ABC_membrane_3 PF13748.6 EMT50482.1 - 0.17 11.1 2.5 0.17 11.1 0.6 1.9 2 0 0 2 2 2 0 ABC transporter transmembrane region MFS_1 PF07690.16 EMT50483.1 - 3.3e-57 194.0 51.6 2.1e-35 122.3 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT50483.1 - 2.7e-16 59.4 25.9 1.6e-07 30.5 8.7 3.2 1 1 2 3 3 3 3 MFS_1 like family Sugar_tr PF00083.24 EMT50483.1 - 1.2e-12 47.4 37.0 3.3e-07 29.6 13.2 3.4 1 1 1 3 3 3 3 Sugar (and other) transporter MFS_3 PF05977.13 EMT50483.1 - 1.8e-12 46.5 20.7 2.4e-12 46.0 20.7 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 EMT50483.1 - 9.2e-11 40.9 29.1 5.7e-08 31.7 12.6 2.8 1 1 2 3 3 3 2 MFS/sugar transport protein BT1 PF03092.16 EMT50483.1 - 1.1 7.5 12.4 0.31 9.2 0.1 2.9 3 0 0 3 3 3 0 BT1 family DUF3042 PF11240.8 EMT50483.1 - 3.4 7.8 7.7 6.9 6.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) MFS_1 PF07690.16 EMT50484.1 - 8.5e-10 38.1 47.3 4.7e-07 29.0 35.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT50484.1 - 0.014 13.8 33.0 0.035 12.5 33.0 1.5 1 1 0 1 1 1 0 Transmembrane secretion effector FixQ PF05545.11 EMT50485.1 - 0.51 10.3 3.0 0.67 10.0 3.0 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ NAD_binding_2 PF03446.15 EMT50486.1 - 2.5e-51 174.0 0.1 3.5e-51 173.5 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMT50486.1 - 1.6e-22 80.0 0.5 2.5e-22 79.4 0.5 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EMT50486.1 - 1.1e-08 35.6 0.0 2.8e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EMT50486.1 - 2.8e-07 30.7 0.3 7.8e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EMT50486.1 - 1.3e-06 27.9 0.0 2.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EMT50486.1 - 0.0013 18.3 0.0 0.0031 17.2 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EMT50486.1 - 0.0019 18.1 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EMT50486.1 - 0.0077 16.5 0.0 0.069 13.4 0.0 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain IlvN PF07991.12 EMT50486.1 - 0.013 15.1 0.0 0.034 13.7 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 EMT50486.1 - 0.026 15.0 0.0 0.066 13.6 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EMT50486.1 - 0.044 13.4 0.1 1 8.9 0.1 2.4 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EMT50486.1 - 0.11 12.5 0.1 0.27 11.2 0.1 1.7 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EMT50487.1 - 1.7e-16 60.5 0.0 4.9e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent P5CR_dimer PF14748.6 EMT50487.1 - 1.8e-14 53.8 0.7 3.2e-14 53.0 0.7 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation NAD_binding_2 PF03446.15 EMT50487.1 - 1.4e-05 25.3 0.0 2.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EMT50487.1 - 1.6e-05 25.0 0.0 4.4e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EMT50487.1 - 0.00024 21.4 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EMT50487.1 - 0.0029 17.3 0.3 0.033 13.8 0.3 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EMT50487.1 - 0.0053 17.0 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 EMT50487.1 - 0.0091 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EMT50487.1 - 0.025 15.4 0.0 0.057 14.2 0.0 1.6 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 EMT50487.1 - 0.04 14.3 0.0 0.093 13.2 0.0 1.7 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Zn_peptidase_2 PF04298.12 EMT50488.1 - 2.1e-85 285.6 1.3 2.3e-85 285.4 1.3 1.0 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase OAM_dimer PF16554.5 EMT50488.1 - 0.068 13.6 0.1 7.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Glu_synthase PF01645.17 EMT50489.1 - 6.8e-106 354.5 5.6 9.4e-104 347.5 3.1 2.9 3 0 0 3 3 3 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EMT50489.1 - 1e-68 231.9 0.0 1.3e-65 221.6 0.0 2.2 2 0 0 2 2 2 2 Glutamate synthase central domain GATase_2 PF00310.21 EMT50489.1 - 3.4e-55 187.5 0.0 4.6e-54 183.7 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GXGXG PF01493.19 EMT50489.1 - 6.4e-23 81.3 7.6 2.4e-21 76.2 7.6 2.3 1 1 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 EMT50489.1 - 2e-06 27.1 11.8 0.00041 19.5 5.9 3.2 3 0 0 3 3 3 2 FMN-dependent dehydrogenase GATase_6 PF13522.6 EMT50489.1 - 0.00089 19.5 0.0 0.011 15.9 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase domain IMPDH PF00478.25 EMT50489.1 - 0.0034 16.4 5.2 0.0053 15.8 3.1 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EMT50489.1 - 0.042 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Aminotran_3 PF00202.21 EMT50491.1 - 3.6e-66 223.5 0.0 4.3e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PP2C_2 PF13672.6 EMT50492.1 - 4.5e-08 33.0 0.0 8.9e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EMT50492.1 - 0.0025 17.5 0.0 0.0036 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C ABC_tran PF00005.27 EMT50493.1 - 1.9e-28 99.7 0.0 4.5e-28 98.5 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EMT50493.1 - 2.1e-09 37.6 3.8 2e-05 24.6 0.2 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMT50493.1 - 0.00036 21.0 0.0 0.0006 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EMT50493.1 - 0.00054 19.6 0.1 0.00098 18.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EMT50493.1 - 0.00089 19.1 0.8 0.017 14.8 0.2 2.1 1 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMT50493.1 - 0.0025 17.8 0.1 0.0064 16.4 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EMT50493.1 - 0.003 18.1 0.0 0.0067 17.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 EMT50493.1 - 0.014 15.7 0.7 0.065 13.5 0.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EMT50493.1 - 0.021 13.8 0.1 0.051 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 EMT50493.1 - 0.031 14.0 0.1 0.075 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMT50493.1 - 0.037 13.7 1.4 0.72 9.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain NTF2 PF02136.20 EMT50493.1 - 0.041 14.4 0.0 0.093 13.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF4162 PF13732.6 EMT50493.1 - 0.061 14.1 0.1 2 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) DUF2813 PF11398.8 EMT50493.1 - 0.085 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_7 PF12775.7 EMT50493.1 - 0.088 12.3 0.1 0.72 9.3 0.0 2.3 2 1 1 3 3 3 0 P-loop containing dynein motor region Folliculin_C PF16692.5 EMT50493.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Folliculin C-terminal domain SMC_N PF02463.19 EMT50493.1 - 0.14 11.5 0.1 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF815 PF05673.13 EMT50493.1 - 0.17 11.0 0.5 4.1 6.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF815) ABC2_membrane_6 PF06182.11 EMT50494.1 - 9.4e-20 71.4 16.2 9.4e-20 71.4 16.2 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_6 PF06182.11 EMT50495.1 - 1.2e-51 175.8 16.2 1.4e-51 175.5 16.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Erg28 PF03694.13 EMT50495.1 - 0.38 11.2 4.5 0.6 10.5 3.1 2.1 1 1 1 2 2 2 0 Erg28 like protein UPF0242 PF06785.11 EMT50495.1 - 2 8.5 6.0 0.2 11.8 0.7 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF202 PF02656.15 EMT50495.1 - 2.1 8.9 13.2 9.3 6.8 0.2 3.5 2 2 0 2 2 2 0 Domain of unknown function (DUF202) ECF_trnsprt PF12822.7 EMT50497.1 - 1.9e-24 86.7 16.9 2.1e-24 86.5 16.9 1.0 1 0 0 1 1 1 1 ECF transporter, substrate-specific component Thia_YuaJ PF09515.10 EMT50497.1 - 0.0004 20.4 8.6 0.0004 20.4 8.6 1.9 1 1 1 2 2 2 1 Thiamine transporter protein (Thia_YuaJ) DUF3180 PF11377.8 EMT50497.1 - 0.00043 20.4 0.8 0.00043 20.4 0.8 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF3180) ECF-ribofla_trS PF07155.12 EMT50497.1 - 0.00073 19.6 18.0 0.0064 16.5 18.0 2.3 1 1 0 1 1 1 1 ECF-type riboflavin transporter, S component 5TM-5TMR_LYT PF07694.12 EMT50497.1 - 0.039 13.5 11.2 0.027 14.0 9.8 1.5 1 1 0 1 1 1 0 5TMR of 5TMR-LYT NDUF_B12 PF08122.12 EMT50497.1 - 1.9 8.6 3.6 2.1 8.4 0.9 2.5 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family tRNA-synt_2b PF00587.25 EMT50498.1 - 3.3e-21 76.0 0.1 5.8e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EMT50498.1 - 4.4e-20 71.6 0.0 9.8e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.11 EMT50498.1 - 3.3e-19 68.8 2.6 7.6e-19 67.7 2.6 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal DUF2381 PF09544.10 EMT50498.1 - 0.046 13.3 0.1 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) HAD_2 PF13419.6 EMT50499.1 - 9.1e-46 156.2 0.0 1e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMT50499.1 - 4.2e-21 76.2 0.2 3.1e-20 73.4 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMT50499.1 - 1.4e-11 45.2 0.0 2.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMT50499.1 - 1.9e-09 37.5 0.0 4.5e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 EMT50499.1 - 0.003 17.4 0.0 5.8 6.6 0.0 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EMT50499.1 - 0.17 11.2 0.1 5.7 6.3 0.0 2.6 2 1 1 3 3 3 0 Putative Phosphatase HTH_20 PF12840.7 EMT50500.1 - 1e-08 35.1 0.3 1.9e-08 34.3 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EMT50500.1 - 1.4e-05 24.8 0.1 6.3e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 EMT50500.1 - 0.00026 20.7 0.1 0.0005 19.8 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain DUF2250 PF10007.9 EMT50500.1 - 0.0019 18.3 0.8 0.004 17.2 0.2 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) WASH-7_mid PF14744.6 EMT50500.1 - 0.0085 15.2 0.5 0.01 15.0 0.5 1.1 1 0 0 1 1 1 1 WASH complex subunit 7 MarR_2 PF12802.7 EMT50500.1 - 0.013 15.3 0.3 0.033 14.1 0.1 1.7 2 0 0 2 2 2 0 MarR family HTH_27 PF13463.6 EMT50500.1 - 0.13 12.7 0.2 0.44 11.1 0.1 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain AhpC-TSA PF00578.21 EMT50501.1 - 9.2e-44 148.3 0.0 1.1e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMT50501.1 - 4.3e-26 91.4 0.0 5.2e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EMT50501.1 - 0.00013 22.1 0.0 0.00021 21.4 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme SCO1-SenC PF02630.14 EMT50501.1 - 0.046 13.6 0.1 0.083 12.8 0.1 1.5 1 1 0 1 1 1 0 SCO1/SenC PSY3 PF16836.5 EMT50501.1 - 0.047 13.2 0.0 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description Peptidase_M42 PF05343.14 EMT50502.1 - 4.9e-86 288.4 0.4 5.7e-86 288.1 0.4 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 EMT50502.1 - 3.3e-10 40.0 0.1 1.1e-09 38.3 0.1 1.8 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EMT50502.1 - 0.00057 19.6 0.0 0.79 9.4 0.0 2.5 2 0 0 2 2 2 2 Peptidase family M28 DUF3247 PF11607.8 EMT50502.1 - 0.038 14.2 0.1 0.96 9.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3247) Methyltransf_25 PF13649.6 EMT50503.1 - 9e-21 74.4 0.0 3.1e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT50503.1 - 1.1e-16 61.2 0.1 6.3e-16 58.8 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT50503.1 - 1.7e-16 60.4 0.0 2.1e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT50503.1 - 6.4e-14 52.1 0.0 1.3e-13 51.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT50503.1 - 1.7e-13 51.1 0.0 3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT50503.1 - 3e-10 39.8 0.0 4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EMT50503.1 - 5.9e-08 32.4 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EMT50503.1 - 1.1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase CMAS PF02353.20 EMT50503.1 - 9e-07 28.5 0.1 5.8e-06 25.8 0.1 2.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 EMT50503.1 - 2.1e-06 27.3 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 EMT50503.1 - 6.2e-06 26.0 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) UPF0020 PF01170.18 EMT50503.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 EMT50503.1 - 0.0012 17.9 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 EMT50503.1 - 0.0018 18.2 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EMT50503.1 - 0.004 16.9 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TPMT PF05724.11 EMT50503.1 - 0.0055 16.4 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.13 EMT50503.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 EMT50503.1 - 0.013 16.5 0.0 0.03 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EMT50503.1 - 0.031 14.4 0.0 0.49 10.5 0.0 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ntox28 PF15605.6 EMT50503.1 - 0.043 14.1 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Bacterial toxin 28 tRNA_U5-meth_tr PF05958.11 EMT50503.1 - 0.066 12.2 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_4 PF02390.17 EMT50503.1 - 0.12 11.8 0.0 0.35 10.3 0.0 1.8 1 1 0 2 2 2 0 Putative methyltransferase Methyltransf_18 PF12847.7 EMT50503.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cob_adeno_trans PF01923.18 EMT50504.1 - 6e-58 195.6 0.0 6.9e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DinB_2 PF12867.7 EMT50505.1 - 6.8e-10 39.5 0.2 1.1e-09 38.8 0.2 1.3 1 0 0 1 1 1 1 DinB superfamily MDMPI_N PF11716.8 EMT50505.1 - 0.0001 23.0 0.1 0.00017 22.3 0.1 1.4 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain DUF664 PF04978.12 EMT50505.1 - 0.00039 20.9 0.6 0.0014 19.0 0.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF664) DinB PF05163.12 EMT50505.1 - 0.00053 20.0 0.8 0.0023 17.9 0.8 1.9 1 1 0 1 1 1 1 DinB family DUF1572 PF07609.11 EMT50505.1 - 0.035 13.9 0.5 9.9 5.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) NAD_binding_10 PF13460.6 EMT50506.1 - 6.4e-29 101.1 0.0 9.5e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMT50506.1 - 8.3e-25 87.6 0.0 5.4e-24 85.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMT50506.1 - 3.6e-22 78.7 0.0 6.9e-17 61.4 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMT50506.1 - 3.3e-19 69.1 0.2 9.8e-11 41.3 0.1 3.0 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 EMT50506.1 - 8.2e-17 61.5 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EMT50506.1 - 8.9e-12 45.0 0.0 1.6e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EMT50506.1 - 8e-10 38.3 0.0 0.00026 20.2 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EMT50506.1 - 1.1e-06 28.0 0.0 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EMT50506.1 - 0.0001 22.3 0.1 0.00031 20.7 0.1 1.8 2 1 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 EMT50506.1 - 0.00019 21.7 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 EMT50506.1 - 0.0021 17.5 0.0 0.0033 16.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase ApbA PF02558.16 EMT50506.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EMT50506.1 - 0.11 13.1 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HhH-GPD PF00730.25 EMT50507.1 - 6.2e-24 84.5 0.3 1.1e-23 83.7 0.0 1.5 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EMT50507.1 - 4e-09 35.9 0.0 1.1e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EMT50507.1 - 0.0024 18.2 6.3 0.0024 18.2 6.3 2.2 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III DUF2400 PF09674.10 EMT50507.1 - 0.057 13.4 0.1 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) HHH_5 PF14520.6 EMT50507.1 - 0.058 14.0 0.0 0.74 10.5 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain FUR PF01475.19 EMT50508.1 - 5.5e-38 129.8 0.0 7.2e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_20 PF12840.7 EMT50508.1 - 0.012 15.6 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Type2_restr_D3 PF16902.5 EMT50508.1 - 0.044 13.7 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain HTH_5 PF01022.20 EMT50508.1 - 0.15 11.9 0.0 0.56 10.1 0.0 2.0 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family Glyco_hydro_18 PF00704.28 EMT50509.1 - 2.4e-24 86.6 1.8 3.4e-24 86.2 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cu_amine_oxidN1 PF07833.11 EMT50509.1 - 7.3e-11 42.4 0.0 2.6e-10 40.6 0.0 2.0 1 0 0 1 1 1 1 Copper amine oxidase N-terminal domain SH3_3 PF08239.11 EMT50509.1 - 8.3e-08 32.4 0.3 4.8e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.13 EMT50509.1 - 0.00026 20.7 0.0 0.0027 17.5 0.0 2.6 3 0 0 3 3 3 1 Bacterial SH3 domain DUF4015 PF13200.6 EMT50509.1 - 0.0066 15.5 0.2 0.03 13.4 0.1 1.9 2 0 0 2 2 2 1 Putative glycosyl hydrolase domain DUF4131 PF13567.6 EMT50509.1 - 0.02 14.6 0.0 0.051 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SH3_16 PF18348.1 EMT50509.1 - 0.092 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF2614 PF11023.8 EMT50510.1 - 2.6e-25 88.7 3.8 2.1e-23 82.5 3.8 2.0 1 1 0 1 1 1 1 Zinc-ribbon containing domain zf-ribbon_3 PF13248.6 EMT50510.1 - 0.06 12.8 2.0 1.9 8.0 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC5 PF06221.13 EMT50510.1 - 0.066 13.2 1.4 0.13 12.2 1.4 1.5 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DZR PF12773.7 EMT50510.1 - 0.076 13.0 1.0 0.12 12.4 1.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-LITAF-like PF10601.9 EMT50510.1 - 0.1 12.9 4.2 0.27 11.5 0.9 2.7 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain DUF485 PF04341.12 EMT50510.1 - 0.13 12.2 3.3 0.18 11.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF4112 PF13430.6 EMT50510.1 - 0.17 12.1 1.6 5.6 7.3 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4112) DUF4674 PF15719.5 EMT50510.1 - 0.34 10.9 2.0 8.7 6.3 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4674) zf-H2C2_2 PF13465.6 EMT50510.1 - 0.37 11.3 1.7 0.91 10.1 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double domain CrgA PF06781.12 EMT50510.1 - 1.5 9.0 6.2 1.3 9.1 0.2 2.3 1 1 1 2 2 2 0 Cell division protein CrgA DUF2721 PF11026.8 EMT50510.1 - 6.6 6.6 7.3 24 4.8 7.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) NTF-like PF14540.6 EMT50511.1 - 4.9e-14 52.1 1.4 1.4e-13 50.6 0.2 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase-like HTH_52 PF18576.1 EMT50511.1 - 1.7e-06 28.1 0.1 5e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4037 PF13228.6 EMT50511.1 - 0.0013 19.4 0.0 0.0035 18.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4037) Bunya_G1 PF03557.15 EMT50512.1 - 0.039 12.0 0.0 0.041 11.9 0.0 1.0 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 OMS28_porin PF03532.13 EMT50513.1 - 0.35 10.1 1.2 0.56 9.4 0.8 1.5 1 1 0 1 1 1 0 OMS28 porin MutS_II PF05188.17 EMT50514.1 - 0.0045 17.3 0.0 0.0054 17.0 0.0 1.0 1 0 0 1 1 1 1 MutS domain II DIX PF00778.17 EMT50514.1 - 0.059 13.2 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 DIX domain Abhydrolase_9_N PF15420.6 EMT50515.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus LysR_substrate PF03466.20 EMT50517.1 - 2.8e-38 131.4 0.7 3.6e-38 131.0 0.7 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT50517.1 - 3.5e-20 71.7 0.6 1.1e-19 70.1 0.6 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EMT50517.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Phosphonate-bd PF12974.7 EMT50517.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein MarR_2 PF12802.7 EMT50517.1 - 0.094 12.6 1.5 0.67 9.9 0.1 2.9 3 0 0 3 3 3 0 MarR family HTH_5 PF01022.20 EMT50517.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MFS_1 PF07690.16 EMT50518.1 - 1.1e-30 106.8 52.2 6.9e-19 68.0 32.8 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT50518.1 - 7.6e-05 21.8 9.7 7.6e-05 21.8 9.7 2.9 1 1 0 2 2 2 1 Sugar (and other) transporter S_4TM PF18159.1 EMT50518.1 - 1.1 8.4 3.7 0.31 10.3 0.2 1.9 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Hydrolase_4 PF12146.8 EMT50519.1 - 3.1e-17 62.6 0.0 5e-10 39.1 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMT50519.1 - 1.3e-11 45.6 1.9 5.6e-11 43.5 1.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMT50519.1 - 8.8e-09 35.4 0.1 1.8e-06 27.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 EMT50519.1 - 0.00012 21.7 0.0 0.14 11.7 0.0 2.5 2 1 0 2 2 2 2 Dienelactone hydrolase family PGAP1 PF07819.13 EMT50519.1 - 0.00068 19.4 0.0 0.0032 17.2 0.0 2.0 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_2 PF02230.16 EMT50519.1 - 0.0008 19.3 0.0 0.0032 17.3 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Palm_thioest PF02089.15 EMT50519.1 - 0.0083 16.0 0.0 0.014 15.2 0.0 1.3 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Peptidase_S9 PF00326.21 EMT50519.1 - 0.016 14.7 0.0 0.24 10.8 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 EMT50519.1 - 0.025 14.2 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase LAL_C2 PF18603.1 EMT50519.1 - 0.041 14.1 0.4 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 Abhydrolase_3 PF07859.13 EMT50519.1 - 0.043 13.7 0.0 0.18 11.7 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold UPF0227 PF05728.12 EMT50519.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) FSH1 PF03959.13 EMT50519.1 - 0.18 11.4 0.2 1.2 8.7 0.2 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) CoA_trans PF01144.23 EMT50520.1 - 8.6e-43 146.2 1.2 1e-42 146.0 1.2 1.0 1 0 0 1 1 1 1 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EMT50520.1 - 0.0015 18.5 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DeoRC PF00455.22 EMT50520.1 - 0.039 13.9 0.0 4.9 7.1 0.0 2.5 2 1 0 2 2 2 0 DeoR C terminal sensor domain CoA_trans PF01144.23 EMT50521.1 - 4.2e-81 271.5 0.1 4.7e-81 271.3 0.1 1.0 1 0 0 1 1 1 1 Coenzyme A transferase Mal_decarbox_Al PF16957.5 EMT50521.1 - 0.11 10.7 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter HlyD_3 PF13437.6 EMT50522.1 - 8.4e-15 55.4 4.4 9e-13 48.9 0.4 2.6 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 EMT50522.1 - 1.1e-11 44.4 14.6 7.2e-10 38.4 14.6 2.2 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 EMT50522.1 - 5.1e-09 35.8 0.2 5.1e-09 35.8 0.2 3.7 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 EMT50522.1 - 1.1e-05 25.1 0.8 0.0072 16.1 0.0 3.3 3 0 0 3 3 3 2 Biotin-requiring enzyme RnfC_N PF13375.6 EMT50522.1 - 0.00092 19.1 0.8 0.019 14.9 0.2 2.6 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_2 PF12700.7 EMT50522.1 - 0.0022 16.8 0.8 0.044 12.5 0.0 2.4 1 1 0 2 2 2 1 HlyD family secretion protein PTS_EIIA_1 PF00358.20 EMT50522.1 - 0.0085 15.8 0.1 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ACR_tran PF00873.19 EMT50523.1 - 6e-51 173.2 6.5 5.3e-50 170.1 6.5 2.4 1 1 0 1 1 1 1 AcrB/AcrD/AcrF family VanZ PF04892.12 EMT50524.1 - 8.6e-15 55.5 0.4 1.2e-14 55.1 0.4 1.1 1 0 0 1 1 1 1 VanZ like family Flp1_like PF16982.5 EMT50524.1 - 1.7 8.1 8.6 5.4 6.5 0.3 2.7 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain DUF2568 PF10823.8 EMT50524.1 - 5.7 7.3 11.5 1.9 8.9 0.4 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2568) S1 PF00575.23 EMT50525.1 - 1.5e-17 63.7 2.7 2e-17 63.3 2.7 1.2 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.6 EMT50525.1 - 0.0016 18.5 0.1 0.019 15.0 0.1 2.2 1 1 0 1 1 1 1 S1 domain Peptidase_S9 PF00326.21 EMT50526.1 - 5.3e-25 88.1 0.0 7e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EMT50526.1 - 3.1e-15 56.3 0.0 7.3e-14 51.8 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EMT50526.1 - 1.7e-11 44.2 0.0 5.1e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 EMT50526.1 - 1.6e-09 38.0 0.0 3.4e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 EMT50526.1 - 4.4e-07 29.9 0.0 0.0078 16.0 0.1 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.12 EMT50526.1 - 2.4e-06 26.5 0.0 0.007 15.1 0.0 2.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 EMT50526.1 - 5.3e-06 25.9 0.0 0.0099 15.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMT50526.1 - 9.2e-05 23.1 2.3 0.0012 19.5 2.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EMT50526.1 - 0.00043 20.0 0.0 0.00083 19.1 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EMT50526.1 - 0.0012 18.5 0.2 0.029 14.0 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EMT50526.1 - 0.002 18.0 0.0 0.044 13.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 EMT50526.1 - 0.006 16.1 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 Esterase PHB depolymerase LIP PF03583.14 EMT50526.1 - 0.039 13.3 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Esterase PF00756.20 EMT50526.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.4 1 1 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 EMT50526.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2235 PF09994.9 EMT50526.1 - 0.2 11.0 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF1100 PF06500.11 EMT50526.1 - 0.27 10.0 0.0 0.38 9.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) HATPase_c PF02518.26 EMT50527.1 - 3.1e-23 82.4 0.0 5.3e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT50527.1 - 1.4e-18 66.7 0.5 6e-18 64.6 0.2 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EMT50527.1 - 1.7e-09 37.9 0.0 4.2e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 HAMP domain PAS_9 PF13426.7 EMT50527.1 - 0.0005 20.3 0.0 0.0037 17.5 0.0 2.5 2 1 0 2 2 2 1 PAS domain 4HB_MCP_1 PF12729.7 EMT50527.1 - 0.0095 15.5 0.8 0.0095 15.5 0.8 2.7 3 0 0 3 3 3 1 Four helix bundle sensory module for signal transduction PAS_4 PF08448.10 EMT50527.1 - 0.023 15.0 0.0 0.23 11.7 0.0 2.5 1 1 0 1 1 1 0 PAS fold HATPase_c_3 PF13589.6 EMT50527.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase betaPIX_CC PF16523.5 EMT50527.1 - 0.065 13.1 1.8 0.26 11.2 0.8 2.5 2 0 0 2 2 2 0 betaPIX coiled coil PAS PF00989.25 EMT50527.1 - 0.13 12.3 0.0 28 4.7 0.0 3.1 3 0 0 3 3 3 0 PAS fold Bmp PF02608.14 EMT50528.1 - 2e-46 158.4 0.0 2.4e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Peripla_BP_4 PF13407.6 EMT50528.1 - 1.1e-05 25.2 1.5 0.0023 17.6 1.3 2.1 2 0 0 2 2 2 2 Periplasmic binding protein domain ATP19 PF11022.8 EMT50530.1 - 0.28 11.6 0.8 0.48 10.8 0.8 1.3 1 0 0 1 1 1 0 ATP synthase subunit K Response_reg PF00072.24 EMT50532.1 - 6.8e-27 93.9 1.6 7.5e-27 93.7 1.6 1.0 1 0 0 1 1 1 1 Response regulator receiver domain TadZ_N PF16968.5 EMT50532.1 - 0.093 12.4 0.0 0.17 11.6 0.0 1.6 1 1 1 2 2 2 0 Pilus assembly protein TadZ N-terminal HTH_30 PF13556.6 EMT50533.1 - 2.6e-21 75.2 0.9 5.1e-21 74.2 0.9 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 EMT50533.1 - 4.2e-15 56.0 3.2 5.9e-15 55.5 0.1 2.7 4 0 0 4 4 4 1 GGDEF-like domain Rap1_C PF11626.8 EMT50533.1 - 0.0066 16.5 0.1 0.018 15.1 0.1 1.8 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain CodY PF06018.14 EMT50533.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 CodY GAF-like domain DUF2653 PF10850.8 EMT50533.1 - 0.023 14.9 0.2 0.057 13.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) HTH_8 PF02954.19 EMT50533.1 - 0.039 13.7 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_1 PF00126.27 EMT50533.1 - 0.04 13.9 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Sipho_Gp157 PF05565.11 EMT50533.1 - 0.081 12.9 0.3 0.081 12.9 0.3 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 AlaDh_PNT_C PF01262.21 EMT50534.1 - 3.4e-84 281.4 3.9 3.4e-84 281.4 3.9 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EMT50534.1 - 5.1e-48 162.8 0.1 9e-48 162.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Pyr_redox PF00070.27 EMT50534.1 - 2.2e-06 28.1 0.2 5.8e-06 26.8 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.19 EMT50534.1 - 3.5e-05 23.2 2.7 0.0032 16.8 2.2 3.0 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox_2 PF07992.14 EMT50534.1 - 4.4e-05 22.9 0.1 7.7e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EMT50534.1 - 4.9e-05 22.8 0.1 0.00011 21.6 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMT50534.1 - 0.00015 21.9 0.2 0.00064 19.8 0.1 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EMT50534.1 - 0.00043 20.2 0.3 0.00088 19.2 0.3 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EMT50534.1 - 0.0018 18.5 0.8 0.0047 17.1 0.7 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 EMT50534.1 - 0.006 17.0 0.2 0.012 16.0 0.2 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding GIDA PF01134.22 EMT50534.1 - 0.011 14.8 0.2 0.016 14.3 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 EMT50534.1 - 0.033 14.5 0.5 0.081 13.2 0.3 1.9 2 0 0 2 2 2 0 TrkA-N domain ADH_zinc_N PF00107.26 EMT50534.1 - 0.15 12.1 2.7 0.22 11.5 0.2 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase DAO PF01266.24 EMT50534.1 - 0.25 10.9 5.0 0.35 10.4 2.6 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EMT50534.1 - 0.74 9.1 4.5 1.1 8.5 4.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Spore_GerAC PF05504.11 EMT50535.1 - 2.8e-20 73.2 0.0 4e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal GerA PF03323.13 EMT50536.1 - 7.8e-127 423.6 0.0 1.1e-126 423.1 0.0 1.2 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein ATP-synt_C PF00137.21 EMT50536.1 - 0.85 10.0 5.0 17 5.9 5.0 2.6 1 1 0 1 1 1 0 ATP synthase subunit C Spore_permease PF03845.13 EMT50537.1 - 6.6e-25 87.6 22.9 6.6e-25 87.6 22.9 1.7 1 1 1 2 2 2 1 Spore germination protein TRAP_alpha PF03896.16 EMT50537.1 - 0.52 9.5 1.3 1.2 8.3 0.3 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DHO_dh PF01180.21 EMT50538.1 - 3.3e-93 312.1 0.0 3.9e-93 311.9 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EMT50538.1 - 0.001 18.2 0.6 0.021 13.8 0.7 2.6 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 EMT50538.1 - 0.0019 17.7 0.5 0.0043 16.5 0.2 1.7 2 0 0 2 2 2 1 Nitronate monooxygenase CbiM PF01891.16 EMT50539.1 - 7.5e-54 182.7 18.8 1e-53 182.3 18.8 1.1 1 0 0 1 1 1 1 Cobalt uptake substrate-specific transmembrane region CbiN PF02553.15 EMT50540.1 - 3.4e-32 110.2 0.6 4e-32 110.0 0.6 1.1 1 0 0 1 1 1 1 Cobalt transport protein component CbiN Gram_pos_anchor PF00746.21 EMT50540.1 - 1.5 8.9 3.6 5.9 6.9 0.5 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif CbiQ PF02361.16 EMT50541.1 - 3.9e-39 134.5 14.1 4.9e-39 134.2 14.1 1.1 1 0 0 1 1 1 1 Cobalt transport protein DUF4516 PF14990.6 EMT50541.1 - 0.017 14.8 0.3 0.06 13.1 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) DUF2793 PF10983.8 EMT50541.1 - 0.022 14.6 1.4 0.033 14.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) ABC_tran PF00005.27 EMT50542.1 - 8.1e-28 97.6 0.0 1.2e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT50542.1 - 9.3e-11 42.1 0.2 4.3e-09 36.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EMT50542.1 - 0.00085 19.0 0.1 0.07 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EMT50542.1 - 0.0052 16.2 0.2 0.11 12.0 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT50542.1 - 0.03 14.1 0.1 6.8 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EMT50542.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 EMT50542.1 - 0.18 11.0 0.1 0.3 10.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Radical_SAM PF04055.21 EMT50543.1 - 3.8e-15 56.7 0.0 5.9e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EMT50543.1 - 6.9e-07 29.6 0.0 1.2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EMT50543.1 - 3.9e-05 23.7 0.0 7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain SPASM PF13186.6 EMT50543.1 - 0.00027 21.4 0.0 0.00073 20.0 0.0 1.7 2 0 0 2 2 2 1 Iron-sulfur cluster-binding domain YwiC PF14256.6 EMT50544.1 - 2.6e-40 137.6 20.0 4.6e-40 136.8 8.8 2.2 2 0 0 2 2 2 2 YwiC-like protein DUF5134 PF17197.4 EMT50544.1 - 0.059 13.3 1.7 0.2 11.6 1.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) MFS_1 PF07690.16 EMT50545.1 - 3e-51 174.4 47.1 3e-51 174.4 47.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT50545.1 - 1.6e-07 30.5 13.4 1.6e-07 30.5 13.4 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EMT50545.1 - 0.34 9.3 18.6 0.096 11.1 5.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.20 EMT50545.1 - 3.2 5.9 19.7 0.57 8.4 0.1 3.6 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family YjbR PF04237.13 EMT50546.1 - 5.7e-21 74.9 0.0 6.7e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 YjbR Phage_Gp17 PF17549.2 EMT50546.1 - 0.062 13.3 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Gene Product 17 Kelch_1 PF01344.25 EMT50547.1 - 3.8e-46 154.4 0.0 3.3e-08 33.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EMT50547.1 - 8.4e-35 117.9 0.0 3.8e-05 23.8 0.0 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EMT50547.1 - 5.4e-24 83.2 0.0 0.00039 20.3 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EMT50547.1 - 6.7e-20 70.8 0.0 0.0031 17.5 0.0 6.2 5 1 1 6 6 6 5 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 EMT50547.1 - 3.1e-14 52.7 0.0 0.0011 18.2 0.0 3.5 1 1 3 4 4 4 4 Glyoxal oxidase N-terminus Kelch_3 PF13415.6 EMT50547.1 - 5.9e-14 51.9 0.2 0.011 16.0 0.0 5.9 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EMT50547.1 - 1.2e-08 34.7 0.0 1.7 8.7 0.0 6.1 6 0 0 6 6 6 2 Kelch motif DUF5122 PF17164.4 EMT50547.1 - 1.2e-06 28.7 7.9 7.7 6.9 0.0 6.2 6 0 0 6 6 6 3 Domain of unknown function (DUF5122) beta-propeller WD40 PF00400.32 EMT50547.1 - 0.047 14.6 0.0 27 5.9 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF218 PF02698.17 EMT50547.1 - 0.061 13.4 0.0 16 5.6 0.0 3.7 1 1 2 4 4 4 0 DUF218 domain NHL PF01436.21 EMT50547.1 - 0.15 12.2 4.6 95 3.3 0.0 5.2 6 0 0 6 6 6 0 NHL repeat Bac_globin PF01152.21 EMT50548.1 - 5.7e-27 94.3 0.2 6.3e-27 94.1 0.2 1.0 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 EMT50548.1 - 0.089 12.7 0.6 0.23 11.3 0.6 1.7 1 1 0 1 1 1 0 Protoglobin Gln-synt_C PF00120.24 EMT50549.1 - 7.5e-133 442.8 0.0 8.9e-133 442.5 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EMT50549.1 - 1.8e-26 91.6 0.0 3.5e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain ApbA PF02558.16 EMT50550.1 - 2e-38 131.4 0.0 2.9e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EMT50550.1 - 2e-25 89.4 0.0 2.7e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal FAD_binding_3 PF01494.19 EMT50550.1 - 0.024 13.9 0.6 0.055 12.7 0.3 1.7 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EMT50550.1 - 0.027 14.1 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EMT50550.1 - 0.042 14.4 0.0 0.14 12.7 0.0 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 EMT50550.1 - 0.078 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EMT50550.1 - 0.082 13.6 0.0 0.21 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.6 EMT50550.1 - 0.082 12.8 0.3 0.35 10.7 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H-binding NAD_binding_8 PF13450.6 EMT50550.1 - 0.12 12.6 0.3 0.31 11.3 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMT50550.1 - 0.15 12.7 1.0 0.47 11.0 0.2 2.3 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase LYTB PF02401.18 EMT50551.1 - 8e-83 277.7 0.0 9.1e-83 277.5 0.0 1.0 1 0 0 1 1 1 1 LytB protein CoA_binding_2 PF13380.6 EMT50551.1 - 0.018 15.5 0.4 0.39 11.2 0.0 2.8 2 2 0 2 2 2 0 CoA binding domain LysR_substrate PF03466.20 EMT50551.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 LysR substrate binding domain MFS_1_like PF12832.7 EMT50552.1 - 1.8e-52 178.5 34.1 2.8e-52 177.9 34.1 1.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EMT50552.1 - 1.7e-24 86.4 70.4 1.3e-18 67.1 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 EMT50552.1 - 2.6e-23 82.7 27.3 3.2e-23 82.4 27.3 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 EMT50552.1 - 2.7e-15 56.0 25.8 4e-15 55.5 25.8 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_2 PF13347.6 EMT50552.1 - 2.3e-08 33.0 27.6 2.3e-08 33.0 27.6 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein Cupredoxin_1 PF13473.6 EMT50553.1 - 2.8e-17 62.7 0.0 3.1e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 EMT50553.1 - 0.0032 17.9 0.0 0.0057 17.1 0.0 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu-oxidase_3 PF07732.15 EMT50553.1 - 0.019 14.9 0.4 0.29 11.1 0.4 2.0 1 1 0 1 1 1 0 Multicopper oxidase LysE PF01810.18 EMT50554.1 - 1.5e-26 93.1 17.4 1.7e-26 92.9 17.4 1.0 1 0 0 1 1 1 1 LysE type translocator DUF4079 PF13301.6 EMT50554.1 - 0.078 13.1 3.4 0.11 12.6 2.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) SirB PF04247.12 EMT50554.1 - 0.38 10.9 11.4 0.039 14.1 3.2 2.3 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB CoatB PF10389.9 EMT50554.1 - 7.3 6.5 8.3 0.57 10.1 3.1 1.8 2 0 0 2 2 2 0 Bacteriophage coat protein B Aminotran_1_2 PF00155.21 EMT50555.1 - 1.1e-31 110.3 0.0 1.4e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EMT50555.1 - 3.5e-17 61.8 0.1 3.5e-17 61.8 0.1 2.3 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 EMT50555.1 - 2.1e-05 23.5 0.0 0.00011 21.1 0.0 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase HTH_Crp_2 PF13545.6 EMT50555.1 - 2.6e-05 24.1 0.0 0.0002 21.3 0.0 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 EMT50555.1 - 0.00024 20.9 0.0 0.00077 19.3 0.0 1.8 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EMT50555.1 - 0.0051 16.7 0.0 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 MarR family Rrf2 PF02082.20 EMT50555.1 - 0.0094 16.3 0.0 0.06 13.7 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator HTH_11 PF08279.12 EMT50555.1 - 0.018 14.9 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_CodY PF08222.11 EMT50555.1 - 0.034 13.7 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_36 PF13730.6 EMT50555.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain LisH_2 PF16045.5 EMT50555.1 - 0.21 10.7 1.0 0.51 9.4 0.2 2.2 2 0 0 2 2 2 0 LisH MCPsignal PF00015.21 EMT50556.1 - 2.3e-34 118.7 38.2 1.7e-33 115.8 15.9 3.7 2 2 2 4 4 4 3 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 EMT50556.1 - 6.2e-09 36.0 25.1 0.022 15.0 1.5 5.8 2 2 3 5 5 5 3 Bacterial protein of unknown function (DUF948) HAMP PF00672.25 EMT50556.1 - 6.9e-07 29.5 0.1 6.9e-07 29.5 0.1 3.8 4 2 0 4 4 4 1 HAMP domain BLOC1_2 PF10046.9 EMT50556.1 - 0.0025 18.1 17.7 0.28 11.5 1.0 5.5 3 2 2 5 5 5 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 sCache_3_3 PF17202.4 EMT50556.1 - 0.0029 18.0 0.0 0.014 15.9 0.0 2.2 1 0 0 1 1 1 1 Single cache domain 3 dCache_1 PF02743.18 EMT50556.1 - 0.007 16.2 0.1 0.007 16.2 0.1 3.1 4 0 0 4 4 4 1 Cache domain Arfaptin PF06456.13 EMT50556.1 - 0.029 13.9 11.4 0.35 10.4 1.0 3.2 1 1 1 3 3 3 0 Arfaptin-like domain DUF1664 PF07889.12 EMT50556.1 - 0.036 14.1 25.8 0.94 9.5 4.2 4.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) SfLAP PF11139.8 EMT50556.1 - 0.045 13.2 0.1 0.14 11.6 0.1 1.8 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein HsbA PF12296.8 EMT50556.1 - 0.049 14.1 14.3 0.36 11.3 1.1 3.3 2 1 1 3 3 3 0 Hydrophobic surface binding protein A DUF3739 PF12545.8 EMT50556.1 - 0.085 13.3 1.2 0.27 11.8 0.5 2.2 2 0 0 2 2 1 0 Filamentous haemagglutinin family outer membrane protein Sec34 PF04136.15 EMT50556.1 - 0.11 12.3 11.6 8.1 6.3 0.3 4.4 2 2 1 4 4 4 0 Sec34-like family SIKE PF05769.11 EMT50556.1 - 0.28 11.1 21.3 0.033 14.1 9.1 2.6 1 1 1 2 2 2 0 SIKE family Laminin_II PF06009.12 EMT50556.1 - 0.32 11.0 28.6 1.2 9.2 2.5 4.7 3 2 1 5 5 5 0 Laminin Domain II DUF4200 PF13863.6 EMT50556.1 - 0.48 10.8 14.5 0.95 9.9 1.5 4.1 2 1 1 4 4 3 0 Domain of unknown function (DUF4200) Hormone_1 PF00103.20 EMT50556.1 - 0.88 9.3 2.4 2.1 8.0 0.1 2.6 2 2 1 3 3 3 0 Somatotropin hormone family Fib_alpha PF08702.10 EMT50556.1 - 1 9.5 19.8 3.6 7.8 1.3 4.1 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 EMT50556.1 - 1.3 7.5 18.7 1.5 7.3 8.6 2.4 1 1 0 2 2 2 0 Fusaric acid resistance protein family LXG PF04740.12 EMT50556.1 - 1.4 8.6 19.9 6.4 6.4 2.6 4.5 2 2 3 5 5 5 0 LXG domain of WXG superfamily Mce4_CUP1 PF11887.8 EMT50556.1 - 3.8 6.9 9.8 1.5 8.2 1.2 2.6 1 1 2 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative Syntaxin_2 PF14523.6 EMT50556.1 - 5 7.6 14.8 1.2e+02 3.2 0.3 4.7 1 1 1 3 3 3 0 Syntaxin-like protein DUF2203 PF09969.9 EMT50556.1 - 5.3 7.8 21.2 5.1 7.8 1.6 4.2 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) AAA_13 PF13166.6 EMT50556.1 - 9 4.8 17.4 73 1.8 17.4 1.9 1 1 0 1 1 1 0 AAA domain Coat_F PF07875.12 EMT50557.1 - 5.6e-23 80.9 0.7 9.7e-23 80.2 0.7 1.4 1 0 0 1 1 1 1 Coat F domain DUF1911 PF08929.10 EMT50557.1 - 0.02 15.7 1.1 0.024 15.5 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) DUF3231 PF11553.8 EMT50558.1 - 3.2e-05 23.6 0.4 5.2e-05 22.9 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3231) Coat_F PF07875.12 EMT50558.1 - 0.052 13.8 3.0 0.24 11.6 0.0 2.1 1 1 0 2 2 2 0 Coat F domain AAA_22 PF13401.6 EMT50559.1 - 0.00022 21.5 0.1 0.0018 18.5 0.0 2.3 2 2 0 2 2 2 1 AAA domain IPT PF01745.16 EMT50559.1 - 0.00035 20.1 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase Cytidylate_kin PF02224.18 EMT50559.1 - 0.00042 20.1 1.0 0.58 9.9 0.1 2.2 1 1 1 2 2 2 2 Cytidylate kinase Asp23 PF03780.13 EMT50559.1 - 0.00056 20.3 0.0 1.1 9.8 0.0 2.5 1 1 1 2 2 2 2 Asp23 family, cell envelope-related function ABC_tran PF00005.27 EMT50559.1 - 0.0025 18.3 0.0 0.004 17.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 EMT50559.1 - 0.0063 16.7 0.1 0.019 15.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EMT50559.1 - 0.018 15.3 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMT50559.1 - 0.02 14.5 0.4 0.041 13.4 0.4 1.6 1 1 0 1 1 1 0 AAA domain Radical_SAM_N PF08497.10 EMT50559.1 - 0.028 13.6 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal AAA PF00004.29 EMT50559.1 - 0.054 13.9 0.1 0.13 12.7 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EMT50559.1 - 0.075 12.8 0.1 0.16 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 EMT50559.1 - 0.079 12.5 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_18 PF13238.6 EMT50559.1 - 0.088 13.4 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMT50559.1 - 0.13 12.7 0.2 0.23 11.8 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 EMT50559.1 - 0.21 11.7 0.4 0.65 10.1 0.1 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain P5CR_dimer PF14748.6 EMT50560.1 - 2.3e-37 127.4 1.1 4.7e-37 126.4 1.1 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EMT50560.1 - 4.3e-17 62.5 0.0 1.2e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 EMT50560.1 - 0.0021 18.0 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EMT50560.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Aldedh PF00171.22 EMT50561.1 - 7.5e-25 87.3 0.6 2e-18 66.2 0.2 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family AA_kinase PF00696.28 EMT50562.1 - 3.4e-42 144.7 0.2 4.6e-42 144.3 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EMT50562.1 - 1.1e-14 54.2 0.0 3.2e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 PUA domain Endopep_inhib PF16800.5 EMT50563.1 - 3.8e-09 36.6 0.0 4.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 IseA DL-endopeptidase inhibitor LPAM_1 PF08139.12 EMT50563.1 - 0.016 15.7 0.4 0.033 14.7 0.4 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Aminotran_4 PF01063.19 EMT50563.1 - 0.03 14.2 0.2 0.15 11.9 0.0 2.0 1 1 2 3 3 3 0 Amino-transferase class IV ABC_tran PF00005.27 EMT50566.1 - 8.7e-28 97.5 0.0 1.2e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT50566.1 - 1.8e-09 37.8 0.7 0.00014 21.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMT50566.1 - 0.0017 18.9 0.1 0.0025 18.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EMT50566.1 - 0.053 13.9 0.0 0.09 13.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EMT50566.1 - 0.065 12.9 0.1 0.3 10.8 0.1 1.9 2 1 1 3 3 3 0 AAA domain SRP54 PF00448.22 EMT50566.1 - 0.078 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EMT50566.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EMT50566.1 - 0.19 11.0 0.1 0.73 9.1 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin ABC_tran_2 PF16949.5 EMT50567.1 - 4.3e-16 58.9 30.4 8.4e-16 57.9 30.4 1.5 1 1 0 1 1 1 1 Putative ATP-binding cassette ABC2_membrane PF01061.24 EMT50567.1 - 0.0014 18.1 10.8 0.0014 18.1 10.8 4.3 2 2 2 4 4 4 2 ABC-2 type transporter DUF218 PF02698.17 EMT50567.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 DUF218 domain SLH PF00395.20 EMT50568.1 - 4.3e-13 49.0 0.8 9.6e-09 35.1 0.0 3.5 4 0 0 4 4 4 2 S-layer homology domain 3HCDH_N PF02737.18 EMT50569.1 - 1.9e-44 151.7 0.0 5.5e-44 150.2 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EMT50569.1 - 3.1e-16 59.8 0.4 4.4e-09 36.8 0.0 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 EMT50569.1 - 3.4e-09 36.4 3.5 4.6e-09 36.0 0.1 2.7 4 0 0 4 4 4 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMT50569.1 - 8.6e-08 32.0 0.5 1.5e-07 31.3 0.5 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pyr_redox_2 PF07992.14 EMT50569.1 - 0.001 18.4 1.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 EMT50569.1 - 0.0011 19.1 0.1 0.01 16.0 0.1 2.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EMT50569.1 - 0.011 15.3 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 EMT50569.1 - 0.083 12.9 0.1 3.4 7.6 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thiolase_N PF00108.23 EMT50570.1 - 8.3e-76 254.8 3.3 1.4e-75 254.1 3.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMT50570.1 - 3.4e-52 175.3 0.7 7e-52 174.2 0.7 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMT50570.1 - 2.8e-05 23.8 1.2 6e-05 22.8 0.4 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 EMT50570.1 - 0.038 14.1 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Phage_holin_2_4 PF16082.5 EMT50570.1 - 1.4 8.8 4.7 0.4 10.4 0.4 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Acyl-CoA_dh_1 PF00441.24 EMT50571.1 - 1.6e-36 125.7 3.0 5.8e-36 123.9 0.0 2.7 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMT50571.1 - 2e-27 96.1 0.0 5.7e-27 94.6 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EMT50571.1 - 2.8e-24 85.2 0.0 5.8e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EMT50571.1 - 8.5e-14 52.0 0.3 2.3e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_L18p PF00861.22 EMT50571.1 - 0.22 11.9 1.6 4.3 7.7 0.0 2.7 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Spore_GerAC PF05504.11 EMT50572.1 - 8.8e-20 71.6 0.0 1.8e-19 70.5 0.0 1.5 2 0 0 2 2 2 1 Spore germination B3/ GerAC like, C-terminal GerA PF03323.13 EMT50573.1 - 7.6e-145 483.0 1.5 8.6e-145 482.8 1.5 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein Spore_permease PF03845.13 EMT50574.1 - 7.8e-29 100.5 27.9 7.8e-29 100.5 27.9 1.3 2 0 0 2 2 2 1 Spore germination protein DUF3007 PF11460.8 EMT50574.1 - 0.093 13.0 1.0 0.46 10.8 1.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) DUF4229 PF14012.6 EMT50574.1 - 0.15 12.2 0.3 0.15 12.2 0.3 4.7 5 1 1 6 6 6 0 Protein of unknown function (DUF4229) DUF5422 PF17459.2 EMT50574.1 - 0.17 12.1 7.8 3.1 8.0 7.9 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5422) GerA PF03323.13 EMT50575.1 - 7e-173 575.4 3.9 7.8e-173 575.2 3.9 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein GTP-bdg_N PF13167.6 EMT50575.1 - 0.13 12.9 0.0 0.27 11.9 0.0 1.5 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal Spore_permease PF03845.13 EMT50576.1 - 7.7e-66 222.1 36.5 9.7e-66 221.8 36.5 1.0 1 0 0 1 1 1 1 Spore germination protein Spore_GerAC PF05504.11 EMT50577.1 - 4.4e-28 98.6 0.1 6.3e-28 98.0 0.1 1.2 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal ARD PF03079.14 EMT50578.1 - 4e-40 137.6 0.3 4.4e-40 137.4 0.3 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EMT50578.1 - 3.2e-10 39.6 0.1 5.5e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EMT50578.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_1 PF00190.22 EMT50578.1 - 0.03 13.9 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_4 PF08007.12 EMT50578.1 - 0.14 11.6 0.4 0.26 10.7 0.2 1.5 2 0 0 2 2 2 0 Cupin superfamily protein Aldolase_II PF00596.21 EMT50579.1 - 3e-36 125.1 0.0 3.4e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HAD PF12710.7 EMT50580.1 - 4.4e-18 66.4 0.0 6.3e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EMT50580.1 - 1.2e-11 44.5 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 EMT50580.1 - 3.2e-06 27.6 0.0 0.0004 20.7 0.0 2.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMT50580.1 - 0.055 13.2 0.0 0.84 9.3 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMT50580.1 - 0.093 12.8 1.1 20 5.2 0.0 3.1 2 2 1 3 3 3 0 Haloacid dehalogenase-like hydrolase RuBisCO_large PF00016.20 EMT50581.1 - 5.5e-47 160.4 0.0 3.6e-46 157.7 0.0 1.9 1 1 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain RuBisCO_large_N PF02788.16 EMT50581.1 - 8.5e-06 25.9 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, N-terminal domain PEP_mutase PF13714.6 EMT50581.1 - 0.021 14.3 0.6 0.077 12.4 0.1 2.1 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase Sigma70_r2 PF04542.14 EMT50582.1 - 8.1e-18 64.0 2.5 1.3e-17 63.4 2.5 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT50582.1 - 2.3e-14 52.8 1.1 4.8e-14 51.8 0.3 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT50582.1 - 7.7e-07 28.5 0.4 2.3e-06 27.0 0.4 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 EMT50582.1 - 0.0017 18.1 0.2 0.0088 15.8 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EMT50582.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_17 PF12728.7 EMT50582.1 - 0.017 15.3 0.2 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain GerE PF00196.19 EMT50582.1 - 0.037 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Sigma70_ECF PF07638.11 EMT50582.1 - 0.052 13.4 0.1 0.07 13.0 0.1 1.2 1 0 0 1 1 1 0 ECF sigma factor HTH_38 PF13936.6 EMT50582.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TnsD PF15978.5 EMT50582.1 - 0.062 12.3 0.1 0.13 11.2 0.0 1.5 1 1 0 1 1 1 0 Tn7-like transposition protein D DUF2774 PF11242.8 EMT50582.1 - 0.093 12.9 0.4 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Sigma_reg_C PF13791.6 EMT50583.1 - 9e-36 123.5 0.0 1.3e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Sigma factor regulator C-terminal Sigma_reg_N PF13800.6 EMT50583.1 - 1.4e-12 47.7 0.0 2.3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Sigma factor regulator N-terminal zf-HC2 PF13490.6 EMT50583.1 - 0.024 14.9 1.3 0.069 13.4 1.3 1.8 1 0 0 1 1 1 0 Putative zinc-finger APH PF01636.23 EMT50584.1 - 9.5e-16 58.4 0.0 1.6e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH_6_hur PF04655.14 EMT50584.1 - 0.0044 16.4 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase Choline_kinase PF01633.20 EMT50584.1 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EMT50584.1 - 0.064 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Fructosamine kinase IF-2B PF01008.17 EMT50585.1 - 2.9e-88 295.8 0.0 3.3e-88 295.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Acetyltransf_3 PF13302.7 EMT50586.1 - 2.6e-22 80.0 0.4 3e-22 79.8 0.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT50586.1 - 3.9e-07 30.3 0.0 4.5e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT50586.1 - 5.3e-06 26.6 0.0 7.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EMT50586.1 - 0.0014 18.3 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 EMT50587.1 - 5.4e-40 137.8 7.0 6.9e-40 137.4 7.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMT50587.1 - 2.5e-30 105.8 0.0 5e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT50587.1 - 4e-05 23.1 0.0 0.013 15.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMT50587.1 - 0.00019 21.9 0.2 0.00061 20.2 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT50587.1 - 0.0002 21.6 0.4 0.00088 19.6 0.4 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT50587.1 - 0.002 18.1 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Adeno_IVa2 PF02456.15 EMT50587.1 - 0.003 16.4 0.0 0.55 9.0 0.0 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein IstB_IS21 PF01695.17 EMT50587.1 - 0.0041 16.9 0.1 3.1 7.5 0.1 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein MMR_HSR1 PF01926.23 EMT50587.1 - 0.0043 17.1 0.1 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 EMT50587.1 - 0.0049 17.0 0.2 0.013 15.7 0.1 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain NB-ARC PF00931.22 EMT50587.1 - 0.014 14.6 0.5 0.091 11.9 0.5 2.0 1 1 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EMT50587.1 - 0.04 13.7 2.4 0.058 13.1 0.1 2.4 3 0 0 3 3 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EMT50587.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.6 EMT50587.1 - 0.079 13.5 0.1 1.3 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EMT50587.1 - 0.11 12.2 0.1 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 EMT50587.1 - 0.13 12.6 0.0 0.54 10.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 EMT50587.1 - 0.21 11.2 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 EMT50587.1 - 0.37 11.3 0.8 1 9.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 EMT50588.1 - 7.4e-43 147.2 9.7 7.4e-43 147.2 9.7 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMT50588.1 - 2.2e-30 106.0 0.0 4.5e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT50588.1 - 7.1e-07 28.9 0.1 0.0014 18.1 0.0 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT50588.1 - 0.00022 21.2 0.3 0.069 12.9 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EMT50588.1 - 0.00038 20.5 0.1 0.0018 18.4 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMT50588.1 - 0.0005 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EMT50588.1 - 0.0032 17.7 0.1 0.033 14.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT50588.1 - 0.0049 17.3 1.2 0.037 14.4 1.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 EMT50588.1 - 0.0085 16.2 0.3 0.024 14.7 0.1 1.9 2 0 0 2 2 2 1 Dynamin family Oleosin PF01277.17 EMT50588.1 - 0.0097 15.7 0.5 0.027 14.2 0.5 1.7 1 0 0 1 1 1 1 Oleosin AAA_29 PF13555.6 EMT50588.1 - 0.014 15.1 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 EMT50588.1 - 0.11 12.6 0.4 0.25 11.4 0.4 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_10 PF12846.7 EMT50588.1 - 0.13 11.2 0.1 0.24 10.3 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain MFS_1 PF07690.16 EMT50589.1 - 4.2e-43 147.6 52.9 1e-23 83.8 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT50589.1 - 1.4e-13 50.6 19.5 7.4e-09 35.0 5.3 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EMT50589.1 - 3.1e-11 42.7 22.2 3.1e-07 29.6 8.1 2.0 1 1 1 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 EMT50589.1 - 1.9e-07 30.0 9.3 1.9e-07 30.0 9.3 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 EMT50589.1 - 8.7e-07 28.6 24.4 1.3e-06 28.0 24.4 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB RDD PF06271.12 EMT50591.1 - 4.4e-23 82.1 7.4 7.2e-23 81.3 7.4 1.3 1 1 0 1 1 1 1 RDD family Pex2_Pex12 PF04757.14 EMT50591.1 - 0.003 17.2 0.1 0.0039 16.8 0.1 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Peptidase_S49 PF01343.18 EMT50592.1 - 4.7e-50 169.5 0.0 6.8e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 EMT50592.1 - 1.3e-05 25.2 0.0 0.00074 19.4 0.0 2.2 2 0 0 2 2 2 1 Clp protease PTE PF02126.18 EMT50592.1 - 0.026 14.0 0.0 5.5 6.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotriesterase family SDH_sah PF01972.16 EMT50592.1 - 0.04 12.9 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase ECH_1 PF00378.20 EMT50592.1 - 0.13 11.6 0.5 38 3.5 0.5 3.0 2 1 0 2 2 2 0 Enoyl-CoA hydratase/isomerase ABC_tran PF00005.27 EMT50593.1 - 1.3e-34 119.7 0.0 1.7e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT50593.1 - 1.1e-13 51.7 0.0 7.4e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT50593.1 - 4.5e-09 36.1 0.1 3.6e-05 23.3 0.0 2.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT50593.1 - 8.6e-05 22.4 0.0 0.0028 17.4 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 EMT50593.1 - 0.0002 20.2 0.0 0.0071 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMT50593.1 - 0.00064 20.1 0.0 0.00082 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT50593.1 - 0.00066 20.0 0.0 0.002 18.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMT50593.1 - 0.00067 20.2 0.0 0.0016 19.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMT50593.1 - 0.0007 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EMT50593.1 - 0.00076 18.4 0.1 0.51 9.1 0.1 3.0 2 1 0 2 2 2 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EMT50593.1 - 0.00081 19.3 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 EMT50593.1 - 0.0023 17.1 0.0 0.0044 16.1 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 EMT50593.1 - 0.0028 17.8 0.0 0.0035 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMT50593.1 - 0.0028 17.4 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMT50593.1 - 0.0048 17.4 0.0 0.0076 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EMT50593.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMT50593.1 - 0.019 14.9 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 EMT50593.1 - 0.028 14.2 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA12 PF10443.9 EMT50593.1 - 0.029 13.1 0.0 0.045 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein NACHT PF05729.12 EMT50593.1 - 0.033 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 EMT50593.1 - 0.036 14.5 0.1 0.6 10.5 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EMT50593.1 - 0.09 12.3 0.1 0.91 9.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMT50593.1 - 0.092 13.0 0.0 0.48 10.6 0.0 2.1 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 EMT50593.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea CobU PF02283.16 EMT50593.1 - 0.15 11.7 0.0 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase IstB_IS21 PF01695.17 EMT50593.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Polysacc_deac_1 PF01522.21 EMT50594.1 - 2.1e-31 108.4 0.0 2.8e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EMT50594.1 - 0.011 15.4 0.5 0.018 14.7 0.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_2 PF04748.13 EMT50594.1 - 0.018 14.2 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase DUF2194 PF09960.9 EMT50594.1 - 0.082 11.2 0.1 0.1 10.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Glyco_tran_WecB PF03808.13 EMT50594.1 - 0.15 12.0 0.0 0.78 9.7 0.0 1.9 1 1 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family DUF2797 PF10977.8 EMT50595.1 - 6.6e-84 281.4 0.0 7.7e-84 281.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2797) PDEase_I_N PF08499.12 EMT50597.1 - 0.038 13.9 0.1 0.14 12.0 0.1 2.0 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal ArsC PF03960.15 EMT50598.1 - 3.3e-17 62.2 0.0 3.7e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 EMT50598.1 - 2.7e-06 27.5 0.0 4.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Ish1 PF10281.9 EMT50598.1 - 0.042 14.2 0.3 8.1 6.8 0.1 3.2 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Aminotran_1_2 PF00155.21 EMT50599.1 - 7.5e-60 203.0 0.0 8.7e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2888 PF11135.8 EMT50599.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2888) DegT_DnrJ_EryC1 PF01041.17 EMT50599.1 - 0.048 13.0 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AhpC-TSA PF00578.21 EMT50600.1 - 2.8e-40 137.1 0.0 3.3e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMT50600.1 - 2.2e-15 56.6 0.0 2.5e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 EMT50600.1 - 0.0025 17.7 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC 1-cysPrx_C PF10417.9 EMT50600.1 - 0.0033 17.2 0.0 0.0074 16.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.21 EMT50601.1 - 6.2e-14 52.0 0.0 7.1e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMT50601.1 - 1.1e-08 34.9 0.0 1.3e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 EMT50601.1 - 1.5e-05 25.4 0.0 2.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMT50601.1 - 3.7e-05 24.0 0.0 4.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 EMT50601.1 - 9e-05 22.4 0.3 0.025 14.6 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin GCV_H PF01597.19 EMT50602.1 - 9.2e-49 164.4 1.2 1e-48 164.3 1.2 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EMT50602.1 - 0.00024 20.9 0.2 0.00063 19.5 0.2 1.7 1 1 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 EMT50602.1 - 0.078 12.9 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain MT0933_antitox PF14013.6 EMT50603.1 - 0.016 15.5 0.3 0.016 15.5 0.3 3.7 3 1 0 3 3 3 0 MT0933-like antitoxin protein ApoLp-III PF07464.11 EMT50603.1 - 0.94 9.6 3.2 2.8 8.0 0.1 2.5 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Transposase_mut PF00872.18 EMT50604.1 - 7.9e-19 67.7 0.0 9.6e-19 67.5 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family IL10 PF00726.17 EMT50604.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 1 1 2 2 2 0 Interleukin 10 Acetyltransf_1 PF00583.25 EMT50605.1 - 1.1e-19 70.7 0.0 1.4e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT50605.1 - 5.2e-15 55.5 0.0 6.5e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT50605.1 - 6.9e-13 48.8 0.0 9.1e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EMT50605.1 - 1.3e-06 28.6 0.1 1.6e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT50605.1 - 4e-06 26.9 0.0 0.0002 21.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EMT50605.1 - 7.1e-06 25.8 0.0 8.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 EMT50605.1 - 8.9e-06 25.6 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EMT50605.1 - 3.7e-05 23.9 0.0 4.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMT50605.1 - 3.9e-05 24.4 0.0 4.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FMN_dh PF01070.18 EMT50605.1 - 0.017 14.1 0.1 0.023 13.7 0.1 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Acetyltransf_CG PF14542.6 EMT50605.1 - 0.088 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 EMT50605.1 - 0.1 12.3 0.1 0.45 10.2 0.0 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain DUF1491 PF07372.12 EMT50605.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1491) DAO PF01266.24 EMT50607.1 - 4.8e-52 177.7 0.0 5.4e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMT50607.1 - 3.5e-08 33.0 0.0 0.0017 17.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT50607.1 - 1.3e-06 27.9 0.0 0.044 13.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT50607.1 - 5.7e-06 25.3 0.1 0.033 12.9 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 EMT50607.1 - 5.9e-06 26.4 0.3 4.9e-05 23.5 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EMT50607.1 - 1.4e-05 24.5 0.1 2.4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EMT50607.1 - 3.1e-05 23.4 0.1 5e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EMT50607.1 - 0.00034 19.8 0.2 0.00056 19.1 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EMT50607.1 - 0.0011 18.2 0.1 0.0021 17.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EMT50607.1 - 0.0017 17.8 0.5 0.0017 17.8 0.5 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 EMT50607.1 - 0.0019 17.8 0.1 0.0029 17.3 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EMT50607.1 - 0.018 15.6 0.0 1.2 9.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EMT50607.1 - 0.088 12.7 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 EMT50607.1 - 0.13 11.5 0.0 0.47 9.7 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EMT50607.1 - 0.23 10.5 0.1 0.49 9.4 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein MCPsignal PF00015.21 EMT50608.1 - 4.4e-50 169.9 58.4 4.7e-49 166.5 25.7 4.3 2 1 2 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 EMT50608.1 - 1.8e-18 66.7 10.5 1.8e-18 66.7 10.5 5.2 2 2 2 4 4 4 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 EMT50608.1 - 6.2e-10 39.3 0.1 6.2e-10 39.3 0.1 5.5 5 1 1 6 6 5 1 HAMP domain BLOC1_2 PF10046.9 EMT50608.1 - 0.0021 18.3 31.3 0.039 14.3 0.1 6.2 4 3 2 6 6 6 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 EMT50608.1 - 0.0032 16.8 7.3 0.0032 16.8 7.3 4.8 2 2 1 4 4 4 1 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 EMT50608.1 - 0.029 14.6 1.0 0.029 14.6 1.0 5.6 5 1 1 6 6 6 0 Seryl-tRNA synthetase N-terminal domain Sec34 PF04136.15 EMT50608.1 - 0.031 14.2 25.2 0.65 9.9 0.4 5.3 4 2 1 5 5 5 0 Sec34-like family cNMP_binding PF00027.29 EMT50608.1 - 0.078 13.1 0.0 2.7 8.1 0.0 2.9 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain DUF1664 PF07889.12 EMT50608.1 - 0.088 12.8 29.7 0.033 14.2 4.4 5.1 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) DUF1848 PF08902.11 EMT50608.1 - 0.11 12.3 2.3 0.29 10.8 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1848) DUF948 PF06103.11 EMT50608.1 - 0.12 12.6 39.5 0.11 12.8 6.2 6.9 4 3 3 7 7 7 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 EMT50608.1 - 2.2 8.7 26.3 4.8 7.6 4.4 6.2 2 2 2 4 4 4 0 Syntaxin-like protein Laminin_II PF06009.12 EMT50608.1 - 2.6 8.1 37.9 0.49 10.4 3.5 5.7 3 3 3 6 6 6 0 Laminin Domain II Tweety PF04906.13 EMT50608.1 - 5 5.7 24.4 1.2 7.7 4.4 4.2 3 2 0 3 3 3 0 Tweety Folliculin PF11704.8 EMT50608.1 - 9.2 6.1 20.0 0.058 13.3 2.6 3.4 3 1 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport FhuF PF06276.12 EMT50609.1 - 2.3e-13 50.9 0.3 3.5e-13 50.3 0.3 1.3 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter FhuF_C PF11575.8 EMT50609.1 - 0.019 14.9 11.3 0.04 13.8 11.3 1.6 1 0 0 1 1 1 0 FhuF 2Fe-2S C-terminal domain Zip PF02535.22 EMT50610.1 - 8.9e-17 61.3 21.9 2.8e-13 49.8 8.8 2.1 1 1 0 2 2 2 2 ZIP Zinc transporter Mntp PF02659.15 EMT50610.1 - 0.034 13.9 0.3 0.034 13.9 0.3 2.7 2 1 0 2 2 2 0 Putative manganese efflux pump Phage_holin_3_7 PF05449.11 EMT50610.1 - 0.47 10.5 5.4 2.6 8.1 0.2 3.0 2 1 1 3 3 3 0 Putative 3TM holin, Phage_holin_3 DUF1129 PF06570.11 EMT50610.1 - 0.59 9.6 2.9 2.7 7.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Peptidase_U4 PF03419.13 EMT50610.1 - 3.2 6.9 12.8 3.3 6.9 2.1 2.1 1 1 0 2 2 2 0 Sporulation factor SpoIIGA MotA_ExbB PF01618.16 EMT50611.1 - 1.2e-30 105.9 5.2 2.8e-29 101.5 0.0 3.1 2 1 1 3 3 3 1 MotA/TolQ/ExbB proton channel family DUF3054 PF11255.8 EMT50611.1 - 0.039 14.5 6.6 0.2 12.2 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) YwiC PF14256.6 EMT50611.1 - 0.045 14.1 0.4 0.045 14.1 0.4 2.3 2 0 0 2 2 2 0 YwiC-like protein DsbD_2 PF13386.6 EMT50611.1 - 0.066 13.1 5.2 2.4 8.0 0.5 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region SNARE_assoc PF09335.11 EMT50611.1 - 0.17 12.3 0.2 0.17 12.3 0.2 2.5 2 1 0 2 2 2 0 SNARE associated Golgi protein DUF2207 PF09972.9 EMT50611.1 - 0.23 10.2 2.3 6.2 5.5 1.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) BCLP PF12304.8 EMT50611.1 - 0.87 9.1 4.5 1.9 8.0 0.6 2.6 2 1 1 3 3 3 0 Beta-casein like protein MgtE PF01769.16 EMT50611.1 - 1.2 9.5 8.3 12 6.3 3.8 2.2 2 0 0 2 2 2 0 Divalent cation transporter RseC_MucC PF04246.12 EMT50611.1 - 2.1 8.3 4.2 1.7 8.6 0.2 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SpoIIIAC PF06686.11 EMT50611.1 - 5.4 7.3 13.1 0.8 9.9 2.4 3.1 2 1 1 3 3 3 0 Stage III sporulation protein AC/AD protein family MotB_plug PF13677.6 EMT50612.1 - 4e-20 71.2 0.9 1e-19 69.9 0.5 1.9 2 0 0 2 2 2 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 EMT50612.1 - 2.4e-19 69.5 0.0 4.5e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 OmpA family Pex24p PF06398.11 EMT50612.1 - 0.12 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin O-antigen_lig PF13425.6 EMT50612.1 - 0.28 9.9 0.0 0.38 9.5 0.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Hydrolase_4 PF12146.8 EMT50613.1 - 1.7e-15 57.0 0.1 2.5e-13 49.9 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMT50613.1 - 3.2e-10 40.1 0.2 7.4e-08 32.3 0.1 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 EMT50613.1 - 2.3e-09 36.4 0.0 3.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 EMT50613.1 - 5.4e-09 37.0 2.3 1.4e-08 35.6 2.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 EMT50613.1 - 2.7e-05 23.4 0.0 6.3e-05 22.2 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 EMT50613.1 - 5.2e-05 22.8 0.0 0.00012 21.6 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 EMT50613.1 - 0.00062 19.6 0.0 0.0088 15.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EMT50613.1 - 0.00062 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF818 PF05677.12 EMT50613.1 - 0.001 18.1 0.0 0.0015 17.6 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) UPF0227 PF05728.12 EMT50613.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 EMT50613.1 - 0.0057 16.5 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.18 EMT50613.1 - 0.0097 15.5 0.0 0.093 12.3 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF676 PF05057.14 EMT50613.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 EMT50613.1 - 0.032 14.1 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_2 PF02230.16 EMT50613.1 - 0.12 12.2 0.1 3.7 7.3 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase APH PF01636.23 EMT50614.1 - 2.1e-27 96.6 3.0 2.4e-27 96.4 3.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EMT50614.1 - 0.024 13.5 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 EMT50614.1 - 0.23 10.7 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase LMWPc PF01451.21 EMT50616.1 - 3.5e-42 144.2 0.0 3.9e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase HATPase_c PF02518.26 EMT50617.1 - 9.6e-16 58.3 0.0 2.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT50617.1 - 2.1e-13 50.1 2.4 3.8e-13 49.3 0.1 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 EMT50617.1 - 2.9e-12 46.6 0.0 7.5e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EMT50617.1 - 5.9e-08 32.6 0.0 2.1e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EMT50617.1 - 3.6e-07 30.4 0.1 1.4e-06 28.5 0.1 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EMT50617.1 - 8e-07 29.3 0.0 1.9e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 EMT50617.1 - 1.3e-05 25.0 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 GHKL domain PAS_7 PF12860.7 EMT50617.1 - 0.0041 17.3 0.0 0.029 14.5 0.0 2.4 2 0 0 2 2 2 1 PAS fold Cytadhesin_P30 PF07271.11 EMT50617.1 - 0.071 12.7 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 Spore_III_AB PF09548.10 EMT50617.1 - 0.099 12.7 4.9 1.8 8.7 0.0 2.9 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Sigma54_activat PF00158.26 EMT50618.1 - 1.4e-71 239.6 0.0 2.8e-71 238.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 EMT50618.1 - 1.4e-27 96.0 0.2 3.4e-27 94.8 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 EMT50618.1 - 1e-21 77.5 0.0 3.4e-21 75.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 EMT50618.1 - 9.1e-12 44.6 2.1 9.1e-12 44.6 2.1 2.4 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 EMT50618.1 - 6.3e-08 32.7 0.0 2e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMT50618.1 - 3.5e-05 23.3 0.3 0.0081 15.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI HTH_50 PF18024.1 EMT50618.1 - 5.3e-05 22.8 0.3 0.00015 21.3 0.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain AAA PF00004.29 EMT50618.1 - 6.6e-05 23.3 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EMT50618.1 - 0.0073 16.4 0.0 0.02 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) HTH_30 PF13556.6 EMT50618.1 - 0.008 16.0 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 EMT50618.1 - 0.015 15.1 0.3 0.051 13.4 0.3 1.9 1 0 0 1 1 1 0 Homeodomain-like domain AAA_16 PF13191.6 EMT50618.1 - 0.02 15.3 0.4 0.05 14.0 0.1 2.0 2 0 0 2 2 1 0 AAA ATPase domain MCM PF00493.23 EMT50618.1 - 0.031 13.4 0.0 0.097 11.8 0.0 1.7 1 1 0 1 1 1 0 MCM P-loop domain Parvo_NS1 PF01057.17 EMT50618.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF3479 PF11965.8 EMT50618.1 - 0.097 12.8 0.5 0.27 11.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3479) TIP49 PF06068.13 EMT50618.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain SCFA_trans PF02667.14 EMT50619.1 - 1.6e-159 531.7 27.4 1.8e-159 531.6 27.4 1.0 1 0 0 1 1 1 1 Short chain fatty acid transporter ABG_transport PF03806.13 EMT50619.1 - 5.3e-07 28.2 3.2 5.3e-07 28.2 3.2 2.1 2 0 0 2 2 2 1 AbgT putative transporter family DcuC PF03606.15 EMT50619.1 - 4.8e-05 22.0 12.6 4.8e-05 22.0 12.6 2.8 2 1 0 2 2 2 2 C4-dicarboxylate anaerobic carrier ABC_tran PF00005.27 EMT50620.1 - 5.3e-40 137.1 4.4 1.1e-20 74.6 0.1 3.6 3 2 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EMT50620.1 - 5.2e-09 36.4 15.2 3.4e-06 27.1 0.1 4.2 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT50620.1 - 1.2e-06 28.1 0.5 0.013 15.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EMT50620.1 - 2.7e-06 27.0 7.3 0.00053 19.5 0.4 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMT50620.1 - 3.4e-05 24.4 9.9 0.023 15.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EMT50620.1 - 0.00017 21.6 0.0 0.31 11.1 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMT50620.1 - 0.00051 20.0 0.6 0.67 9.8 0.1 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 EMT50620.1 - 0.001 19.6 0.6 0.024 15.2 0.0 2.9 3 1 0 3 3 3 1 AAA domain Roc PF08477.13 EMT50620.1 - 0.002 18.3 0.6 1.6 9.0 0.1 3.5 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EMT50620.1 - 0.0041 16.9 0.5 1.6 8.4 0.1 3.1 3 0 0 3 3 3 1 AAA domain Pox_A32 PF04665.12 EMT50620.1 - 0.0051 16.3 0.2 2.9 7.3 0.0 2.5 2 0 0 2 2 2 2 Poxvirus A32 protein NACHT PF05729.12 EMT50620.1 - 0.0056 16.6 1.7 2.9 7.8 0.2 2.8 2 2 0 3 3 3 2 NACHT domain MobB PF03205.14 EMT50620.1 - 0.0062 16.4 0.0 0.7 9.8 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 EMT50620.1 - 0.0067 16.8 1.3 0.2 12.1 0.0 3.0 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 EMT50620.1 - 0.0075 16.3 5.0 0.39 10.8 0.0 3.1 3 1 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 EMT50620.1 - 0.012 16.0 0.0 0.67 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 EMT50620.1 - 0.014 15.4 0.0 3.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EMT50620.1 - 0.021 14.4 0.1 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EMT50620.1 - 0.021 15.2 1.0 15 6.1 0.1 3.4 3 1 0 3 3 3 0 RNA helicase cobW PF02492.19 EMT50620.1 - 0.026 14.1 0.2 8.3 6.0 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EMT50620.1 - 0.04 13.8 0.5 5.2 6.9 0.0 2.6 2 0 0 2 2 2 0 NTPase SbcCD_C PF13558.6 EMT50620.1 - 0.041 14.1 0.0 6.6 7.0 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EMT50620.1 - 0.045 13.5 0.5 0.045 13.5 0.5 3.9 1 1 1 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 EMT50620.1 - 0.052 13.3 3.0 0.14 11.9 0.1 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran_Xtn PF12848.7 EMT50620.1 - 0.061 13.4 9.0 0.47 10.5 8.6 2.3 1 1 1 2 2 2 0 ABC transporter ATP-synt_ab PF00006.25 EMT50620.1 - 0.064 12.9 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 EMT50620.1 - 0.081 13.0 0.8 17 5.4 0.0 3.3 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EMT50620.1 - 0.09 12.0 2.8 2.9 7.1 0.0 2.5 2 1 0 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.6 EMT50620.1 - 0.12 12.6 0.0 30 4.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain TIR-like PF10137.9 EMT50621.1 - 2e-27 95.5 0.0 7.5e-27 93.6 0.0 1.9 2 0 0 2 2 2 1 Predicted nucleotide-binding protein containing TIR-like domain PA28_alpha PF02251.18 EMT50622.1 - 0.13 12.3 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit DUF21 PF01595.20 EMT50623.1 - 2.6e-53 180.3 2.9 2.6e-53 180.3 2.9 1.7 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 EMT50623.1 - 1.7e-15 56.8 0.2 3.5e-15 55.8 0.2 1.5 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 EMT50623.1 - 6.6e-15 55.3 0.5 2.5e-08 34.2 0.1 2.6 2 0 0 2 2 2 2 CBS domain Peptidase_M50 PF02163.22 EMT50624.1 - 6.8e-12 45.2 8.4 7e-06 25.5 0.8 3.1 2 1 1 4 4 4 2 Peptidase family M50 Fe-S_biosyn PF01521.20 EMT50625.1 - 6.9e-08 32.7 0.0 8.7e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3905 PF13045.6 EMT50626.1 - 6.6e-46 154.2 1.1 1.2e-45 153.3 1.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3905) SspK PF08176.12 EMT50627.1 - 2.5e-07 30.8 0.5 4.9e-07 29.9 0.5 1.4 1 1 0 1 1 1 1 Small acid-soluble spore protein K family DUF3886 PF13025.6 EMT50628.1 - 6e-11 42.4 17.4 6e-11 42.4 17.4 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3886) Herpes_UL56 PF04534.12 EMT50628.1 - 0.1 12.1 0.3 0.1 12.1 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein tRNA_bind_2 PF13725.6 EMT50628.1 - 1 9.0 8.8 1.1 8.9 8.8 1.1 1 0 0 1 1 1 0 Possible tRNA binding domain DUF2975 PF11188.8 EMT50630.1 - 0.17 11.8 0.5 0.17 11.8 0.5 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2975) MRAP PF15183.6 EMT50630.1 - 1.4 8.9 4.1 0.26 11.3 0.8 1.4 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family MacB_PCD PF12704.7 EMT50631.1 - 6.1e-35 121.3 6.3 1.1e-34 120.5 0.0 2.3 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 EMT50631.1 - 5.8e-17 61.9 7.1 1.5e-16 60.6 2.6 2.9 3 0 0 3 3 3 1 FtsX-like permease family DUF4064 PF13273.6 EMT50631.1 - 0.0059 16.9 12.8 0.037 14.3 10.1 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF4064) Med29 PF11568.8 EMT50631.1 - 0.061 13.6 0.4 0.12 12.5 0.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 29 ABC2_membrane_3 PF12698.7 EMT50631.1 - 0.08 12.0 14.9 0.32 10.1 15.0 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4118 PF13493.6 EMT50631.1 - 0.63 9.9 3.9 2.5 8.0 3.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4118) DUF2207 PF09972.9 EMT50631.1 - 2.6 6.7 6.7 11 4.6 6.7 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC2_membrane_2 PF12679.7 EMT50631.1 - 8.2 5.6 9.5 51 3.0 9.7 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 EMT50632.1 - 1.2e-33 116.5 0.0 1.8e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT50632.1 - 3.1e-08 33.3 0.3 7e-06 25.6 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT50632.1 - 1.2e-06 28.5 0.1 0.0023 17.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT50632.1 - 0.00048 19.8 0.0 0.0009 18.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EMT50632.1 - 0.0013 18.9 0.5 0.012 15.8 0.5 2.2 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EMT50632.1 - 0.0014 17.7 0.1 0.019 14.0 0.0 2.0 1 1 1 2 2 2 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EMT50632.1 - 0.0018 18.2 0.2 0.0057 16.6 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EMT50632.1 - 0.0024 18.1 0.2 0.016 15.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EMT50632.1 - 0.0031 17.2 0.1 0.025 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EMT50632.1 - 0.0056 16.3 0.0 0.16 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Resolvase PF00239.21 EMT50632.1 - 0.017 15.2 0.5 0.1 12.7 0.4 2.1 1 1 1 2 2 2 0 Resolvase, N terminal domain MMR_HSR1 PF01926.23 EMT50632.1 - 0.023 14.8 0.1 0.09 12.9 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EMT50632.1 - 0.025 15.0 0.0 0.039 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 EMT50632.1 - 0.036 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_23 PF13476.6 EMT50632.1 - 0.044 14.3 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMT50632.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EMT50632.1 - 0.084 12.6 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain IIGP PF05049.13 EMT50632.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RNA_helicase PF00910.22 EMT50632.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase HlyD_D23 PF16576.5 EMT50633.1 - 1.4e-18 67.0 14.5 1.8e-16 60.0 14.5 2.6 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EMT50633.1 - 1.5e-18 67.5 4.4 1.2e-15 58.1 1.2 3.0 3 0 0 3 3 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EMT50633.1 - 2.2e-10 40.2 9.4 6e-08 32.4 0.1 4.0 3 1 0 3 3 3 2 Biotin-lipoyl like HlyD_2 PF12700.7 EMT50633.1 - 1.4e-08 33.9 14.5 1.2e-06 27.5 14.5 2.7 1 1 0 1 1 1 1 HlyD family secretion protein Biotin_lipoyl PF00364.22 EMT50633.1 - 1.1e-07 31.5 2.3 0.0058 16.4 0.0 3.3 3 0 0 3 3 3 2 Biotin-requiring enzyme Peptidase_M23 PF01551.22 EMT50633.1 - 5.1e-06 26.6 0.2 0.00012 22.2 0.1 2.5 2 0 0 2 2 2 1 Peptidase family M23 PTS_EIIA_1 PF00358.20 EMT50633.1 - 0.001 18.9 0.9 2.6 7.8 0.1 3.8 2 1 1 3 3 3 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 OEP PF02321.18 EMT50633.1 - 0.0041 16.9 10.9 0.0041 16.9 10.9 3.0 3 0 0 3 3 3 1 Outer membrane efflux protein QRPTase_N PF02749.16 EMT50633.1 - 0.006 16.6 0.1 0.21 11.6 0.1 2.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain RnfC_N PF13375.6 EMT50633.1 - 0.0061 16.5 0.7 0.31 11.0 0.1 2.9 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain Atg14 PF10186.9 EMT50633.1 - 0.0097 15.0 11.2 0.013 14.6 11.2 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 EMT50633.1 - 0.025 13.9 15.6 0.045 13.1 15.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2218 PF09981.9 EMT50633.1 - 0.1 13.0 1.8 0.26 11.7 1.8 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) SYF2 PF08231.12 EMT50633.1 - 0.13 12.7 6.1 0.19 12.1 6.1 1.2 1 0 0 1 1 1 0 SYF2 splicing factor Spc7 PF08317.11 EMT50633.1 - 0.14 11.1 14.8 0.21 10.4 14.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 EMT50633.1 - 0.87 9.9 18.3 4.5 7.6 0.8 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain Syntaxin-6_N PF09177.11 EMT50633.1 - 1.3 9.6 7.0 9 6.9 3.4 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal BRE1 PF08647.11 EMT50633.1 - 2.8 8.1 15.8 3.1 7.9 5.2 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TMPIT PF07851.13 EMT50633.1 - 9.4 5.4 6.4 15 4.7 6.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein PGI PF00342.19 EMT50634.1 - 1.7e-22 79.7 0.0 2.5e-21 75.8 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucose isomerase HTH_17 PF12728.7 EMT50635.1 - 2.8e-07 30.6 0.0 3.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MerR_2 PF13591.6 EMT50635.1 - 0.053 13.4 0.6 0.071 13.0 0.6 1.2 1 0 0 1 1 1 0 MerR HTH family regulatory protein DAO PF01266.24 EMT50636.1 - 6.9e-68 229.8 2.5 7.7e-68 229.6 2.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMT50636.1 - 3.2e-06 27.3 0.1 6.6e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMT50636.1 - 5.7e-06 25.7 7.1 0.00011 21.5 7.1 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EMT50636.1 - 0.00041 20.9 1.3 0.0012 19.4 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMT50636.1 - 0.00085 18.6 0.8 0.041 13.1 0.8 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT50636.1 - 0.0013 17.5 0.8 0.12 11.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 EMT50636.1 - 0.0016 17.8 0.8 0.0025 17.1 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMT50636.1 - 0.0044 16.3 0.2 0.42 9.8 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMT50636.1 - 0.011 15.1 3.0 0.36 10.1 3.0 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EMT50636.1 - 0.13 11.5 0.5 0.29 10.4 0.5 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 EMT50636.1 - 0.14 12.6 0.0 0.62 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EMT50636.1 - 0.14 11.1 0.6 0.29 10.1 0.2 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein HHH PF00633.23 EMT50637.1 - 0.2 11.6 9.0 76 3.5 0.1 4.7 5 0 0 5 5 5 0 Helix-hairpin-helix motif YugN PF08868.10 EMT50638.1 - 1.7e-42 144.4 0.0 1.9e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 YugN-like family NUDIX PF00293.28 EMT50639.1 - 1e-18 67.6 0.6 1.2e-18 67.4 0.6 1.1 1 0 0 1 1 1 1 NUDIX domain NAD_kinase PF01513.21 EMT50640.1 - 6.5e-24 84.6 0.0 7.7e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EMT50640.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MOSC PF03473.17 EMT50641.1 - 6e-20 71.6 0.0 8.8e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EMT50641.1 - 3.1e-07 30.3 0.0 4.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain tRNA_edit PF04073.15 EMT50642.1 - 2e-27 95.7 0.0 2.3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain RNase_T PF00929.24 EMT50643.1 - 7.7e-24 85.1 0.0 1.2e-23 84.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF294 PF03445.13 EMT50644.1 - 1.3e-29 102.8 0.0 2.6e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 DUF294_C PF10335.9 EMT50644.1 - 4.3e-25 88.2 0.0 9e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Putative nucleotidyltransferase substrate binding domain Ammonium_transp PF00909.21 EMT50645.1 - 1.1e-116 389.8 36.6 1.3e-116 389.7 36.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 EMT50645.1 - 0.21 11.6 0.2 0.21 11.6 0.2 2.8 2 0 0 2 2 2 0 Bacteriophage P21 holin S Phage_holin_2_3 PF16080.5 EMT50645.1 - 2 8.2 8.9 7 6.5 0.4 3.5 3 0 0 3 3 3 0 Bacteriophage holin family HP1 MFS_1 PF07690.16 EMT50646.1 - 1.6e-23 83.2 73.9 1.6e-21 76.6 43.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT50646.1 - 1.5e-21 76.4 27.8 1.8e-21 76.1 27.8 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector Toprim PF01751.22 EMT50648.1 - 7.5e-05 22.9 0.1 0.00019 21.6 0.1 1.6 1 1 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 EMT50648.1 - 0.0002 21.7 0.0 0.00025 21.4 0.0 1.3 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 EMT50648.1 - 0.00041 20.8 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Toprim domain MerC PF03203.14 EMT50649.1 - 0.012 16.0 1.8 0.012 16.0 1.8 1.0 1 0 0 1 1 1 0 MerC mercury resistance protein Phage_holin_3_6 PF07332.11 EMT50649.1 - 0.052 13.6 4.2 0.057 13.5 4.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF997 PF06196.12 EMT50649.1 - 0.069 13.2 2.0 0.08 12.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF997) DUF4131 PF13567.6 EMT50649.1 - 0.083 12.5 1.8 0.091 12.4 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) BacA PF02673.18 EMT50650.1 - 9.2e-73 245.1 16.5 1.1e-72 244.9 16.5 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA S1_2 PF13509.6 EMT50651.1 - 1.4e-23 82.7 0.0 2.9e-19 68.9 0.0 3.2 3 0 0 3 3 3 2 S1 domain CvfB_WH PF17783.1 EMT50651.1 - 5.8e-22 77.2 0.0 1e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 CvfB-like winged helix domain S1 PF00575.23 EMT50651.1 - 0.027 14.8 0.0 0.41 11.0 0.0 2.7 3 0 0 3 3 3 0 S1 RNA binding domain Na_H_Exchanger PF00999.21 EMT50652.1 - 1.8e-75 254.1 48.2 2.1e-75 253.9 48.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HlyE PF06109.13 EMT50652.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Haemolysin E (HlyE) DctM PF06808.12 EMT50653.1 - 2.7e-99 332.8 41.2 4.6e-99 332.0 41.2 1.3 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component FxsA PF04186.13 EMT50653.1 - 0.018 15.2 6.2 0.018 15.2 6.2 4.7 3 3 0 3 3 3 0 FxsA cytoplasmic membrane protein DUF1850 PF08905.11 EMT50654.1 - 1.9e-24 85.8 0.0 2.7e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1850) NMT1_3 PF16868.5 EMT50655.1 - 2.9e-96 322.3 6.5 3.3e-96 322.1 6.5 1.0 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 EMT50655.1 - 3.3e-12 46.8 1.7 7.4e-12 45.7 1.2 1.8 1 1 1 2 2 2 1 NMT1/THI5 like Phosphonate-bd PF12974.7 EMT50655.1 - 2e-08 34.2 5.2 5.2e-08 32.8 5.2 1.7 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 EMT50655.1 - 3e-06 26.8 3.6 9.4e-06 25.2 3.6 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF4969 PF16339.5 EMT50655.1 - 0.025 14.9 0.0 0.097 13.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) DUF4431 PF14485.6 EMT50655.1 - 0.043 13.6 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) Chorion_3 PF05387.11 EMT50655.1 - 2.4 7.8 6.7 3.8 7.1 6.7 1.3 1 0 0 1 1 1 0 Chorion family 3 HATPase_c PF02518.26 EMT50656.1 - 1.9e-14 54.1 0.0 3.8e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EMT50656.1 - 0.0062 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 EMT50656.1 - 0.0073 16.1 0.0 0.02 14.7 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT50656.1 - 0.051 13.5 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain YcbB PF08664.10 EMT50657.1 - 1.2e-48 164.6 0.0 2e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 YcbB domain Response_reg PF00072.24 EMT50657.1 - 4.9e-18 65.3 0.7 1.3e-17 63.9 0.5 1.8 2 0 0 2 2 2 1 Response regulator receiver domain DUF2600 PF10776.9 EMT50658.1 - 6.6e-138 459.0 0.1 7.6e-138 458.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2600) DUF5325 PF17259.2 EMT50659.1 - 3.3e-18 65.3 0.2 3.5e-18 65.2 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5325) Cyt_c_ox_IV PF12270.8 EMT50659.1 - 0.0036 17.4 0.2 0.0038 17.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV NiFe_hyd_3_EhaA PF17367.2 EMT50659.1 - 0.039 14.1 1.1 0.046 13.9 1.1 1.1 1 0 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A PilZ PF07238.14 EMT50660.1 - 2.8e-12 46.8 0.3 3.6e-11 43.3 0.1 2.0 2 0 0 2 2 2 1 PilZ domain MFS_1 PF07690.16 EMT50661.1 - 3.7e-27 95.2 51.6 2.8e-16 59.4 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT50661.1 - 2.1e-23 82.5 27.5 3e-23 82.0 27.5 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Phage_holin_3_6 PF07332.11 EMT50661.1 - 0.017 15.2 0.7 0.017 15.2 0.7 5.3 3 2 2 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III Trans_reg_C PF00486.28 EMT50662.1 - 8.4e-23 80.3 0.3 2.1e-22 79.0 0.3 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal ComR_TPR PF18710.1 EMT50662.1 - 0.044 13.3 0.2 0.074 12.6 0.2 1.4 1 0 0 1 1 1 0 ComR tetratricopeptide Sigma54_activat PF00158.26 EMT50663.1 - 8.3e-72 240.4 0.2 1.3e-71 239.7 0.2 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT50663.1 - 1.2e-20 74.0 0.0 4.4e-20 72.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 EMT50663.1 - 2.3e-13 49.7 2.6 2.5e-13 49.6 1.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family PAS_9 PF13426.7 EMT50663.1 - 7.8e-11 42.2 0.0 2.3e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EMT50663.1 - 1.4e-10 41.4 0.2 3.4e-10 40.2 0.2 1.7 1 0 0 1 1 1 1 PAS fold PAS_10 PF13596.6 EMT50663.1 - 6.7e-09 36.3 0.1 1.6e-08 35.1 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EMT50663.1 - 1.8e-08 34.4 0.1 6.9e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 PAS fold AAA_5 PF07728.14 EMT50663.1 - 1.3e-06 28.5 0.0 5.6e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMT50663.1 - 5.1e-06 26.0 0.2 0.00032 20.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PAS_8 PF13188.7 EMT50663.1 - 5.2e-06 26.4 0.1 2.2e-05 24.4 0.0 2.1 2 0 0 2 2 1 1 PAS domain HTH_50 PF18024.1 EMT50663.1 - 0.00029 20.4 0.1 0.00074 19.1 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain AAA PF00004.29 EMT50663.1 - 0.0025 18.2 0.0 0.0069 16.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PAS_7 PF12860.7 EMT50663.1 - 0.0047 17.1 0.0 0.028 14.6 0.0 2.3 1 1 0 1 1 1 1 PAS fold OKR_DC_1 PF01276.20 EMT50663.1 - 0.0094 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain SpoVT_C PF15714.5 EMT50663.1 - 0.044 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor NACHT PF05729.12 EMT50663.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain HTH_28 PF13518.6 EMT50663.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Pro_dh PF01619.18 EMT50664.1 - 6e-34 117.9 0.8 8.8e-34 117.4 0.8 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Coat_F PF07875.12 EMT50665.1 - 1.4e-23 82.8 0.6 1.5e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 Coat F domain DUF2383 PF09537.10 EMT50665.1 - 0.075 13.4 0.1 0.14 12.5 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) HhH-GPD PF00730.25 EMT50666.1 - 9e-20 71.1 0.0 1.7e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein OGG_N PF07934.12 EMT50666.1 - 0.00018 21.6 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain Branch_AA_trans PF05525.13 EMT50667.1 - 4e-160 533.4 35.7 4.5e-160 533.2 35.7 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein EamA PF00892.20 EMT50668.1 - 6.6e-46 155.9 49.5 5.8e-23 81.6 19.0 2.0 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 EMT50668.1 - 0.00057 18.9 8.7 0.00057 18.9 8.7 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Acetyltransf_3 PF13302.7 EMT50669.1 - 1.2e-12 48.6 0.0 1.5e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT50669.1 - 1.5e-11 44.5 0.0 4e-11 43.2 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT50669.1 - 1.5e-08 34.6 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT50669.1 - 1.1e-06 28.9 0.0 4.1e-06 27.0 0.0 1.9 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT50669.1 - 3e-06 27.6 0.0 4.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT50669.1 - 0.00035 20.5 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DinB_2 PF12867.7 EMT50670.1 - 1.4e-21 77.3 0.0 1.6e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 EMT50670.1 - 2.2e-11 44.4 0.0 4.1e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF664) DinB PF05163.12 EMT50670.1 - 7.7e-11 42.2 0.0 8.3e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 DinB family DUF1572 PF07609.11 EMT50670.1 - 3e-08 33.6 0.0 0.003 17.4 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1572) MDMPI_N PF11716.8 EMT50670.1 - 0.00032 21.4 0.0 0.15 12.7 0.0 2.1 2 0 0 2 2 2 2 Mycothiol maleylpyruvate isomerase N-terminal domain DUF717 PF05338.12 EMT50670.1 - 0.025 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF717) 4HBT_2 PF13279.6 EMT50671.1 - 4.3e-24 85.4 0.1 5.2e-24 85.1 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 EMT50671.1 - 1.2e-17 64.0 1.3 1.3e-09 37.7 0.1 2.0 1 1 1 2 2 2 2 Acyl-ACP thioesterase 4HBT PF03061.22 EMT50671.1 - 2.2e-15 56.8 0.0 4.3e-15 55.8 0.0 1.5 1 1 0 1 1 1 1 Thioesterase superfamily HAD_2 PF13419.6 EMT50672.1 - 3.9e-26 92.2 0.0 5.4e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMT50672.1 - 3.9e-15 56.7 0.0 5.4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMT50672.1 - 1.5e-10 41.0 0.0 2.6e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EMT50672.1 - 2.8e-07 31.2 0.1 4.3e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EMT50672.1 - 0.0043 16.8 0.0 0.68 9.7 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase NT5C PF06941.12 EMT50672.1 - 0.011 15.7 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) ABC_tran PF00005.27 EMT50673.1 - 2e-28 99.6 0.0 3.5e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT50673.1 - 1.7e-09 37.9 4.3 2.1e-06 27.8 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EMT50673.1 - 4.8e-05 24.0 0.0 0.00016 22.3 0.0 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 EMT50673.1 - 0.00056 19.9 0.1 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EMT50673.1 - 0.005 16.6 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT50673.1 - 0.0051 17.3 0.2 0.0099 16.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EMT50673.1 - 0.0084 16.2 0.5 0.026 14.6 0.4 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.7 EMT50673.1 - 0.048 12.6 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_15 PF13175.6 EMT50673.1 - 0.24 11.1 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_2 PF12679.7 EMT50674.1 - 6.8e-10 38.7 15.9 8.7e-09 35.1 15.9 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 EMT50674.1 - 0.00019 20.7 20.0 0.00019 20.7 20.0 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF1189 PF06691.11 EMT50674.1 - 0.53 9.8 9.5 0.04 13.5 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) PRP9_N PF16958.5 EMT50675.1 - 0.0076 16.3 1.2 0.015 15.3 1.2 1.5 1 1 1 2 2 2 1 Pre-mRNA-splicing factor PRP9 N-terminus Acetyltransf_10 PF13673.7 EMT50676.1 - 6.7e-15 55.2 0.0 8.2e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT50676.1 - 8.1e-12 45.4 0.0 9.6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT50676.1 - 1.5e-10 41.4 0.0 2.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT50676.1 - 0.19 11.9 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase tRNA_edit PF04073.15 EMT50677.1 - 4.2e-21 75.3 0.0 5.3e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain YitT_membrane PF02588.15 EMT50678.1 - 1e-66 224.2 21.6 1.4e-66 223.8 21.6 1.2 1 0 0 1 1 1 1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DUF2179 PF10035.9 EMT50678.1 - 5.9e-22 77.2 0.0 1.1e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2179) Zn_ribbon_2 PF12674.7 EMT50679.1 - 6.5e-32 110.0 1.9 7.3e-32 109.9 1.9 1.0 1 0 0 1 1 1 1 Putative zinc ribbon domain Auto_anti-p27 PF06677.12 EMT50679.1 - 0.26 11.5 3.2 0.21 11.8 1.3 2.0 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) WYL PF13280.6 EMT50680.1 - 5.7e-31 107.9 0.2 1e-30 107.1 0.2 1.4 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 EMT50680.1 - 1.6e-13 50.4 0.1 3.7e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 HTH domain HTH_DeoR PF08220.12 EMT50680.1 - 4.3e-05 23.2 0.0 9.5e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_23 PF13384.6 EMT50680.1 - 0.0018 18.0 0.1 0.0036 17.0 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain PuR_N PF09182.10 EMT50680.1 - 0.0054 16.6 0.4 0.019 14.9 0.4 2.0 1 1 0 1 1 1 1 Bacterial purine repressor, N-terminal Mga PF05043.13 EMT50680.1 - 0.027 15.0 0.0 0.16 12.5 0.0 2.2 2 0 0 2 2 2 0 Mga helix-turn-helix domain Rrf2 PF02082.20 EMT50680.1 - 0.054 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_29 PF13551.6 EMT50680.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_3 PF01381.22 EMT50680.1 - 0.14 12.3 0.0 17 5.5 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix Acetyltransf_1 PF00583.25 EMT50681.1 - 3.6e-07 30.4 0.0 4.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT50681.1 - 0.0017 18.3 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT50681.1 - 0.0027 18.1 0.0 0.0043 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_16 PF05301.11 EMT50681.1 - 0.035 13.9 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 DUF2334 PF10096.9 EMT50682.1 - 0.012 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Glycos_transf_1 PF00534.20 EMT50683.1 - 1.8e-24 86.2 0.0 4e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT50683.1 - 5.2e-20 72.2 0.0 3.5e-19 69.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT50683.1 - 1e-12 48.4 1.0 2.4e-12 47.2 1.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EMT50683.1 - 4.6e-09 36.9 1.5 1.7e-08 35.0 1.5 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EMT50683.1 - 1.9e-05 24.9 0.1 9.4e-05 22.7 0.0 2.1 1 1 1 2 2 2 1 Glycosyl transferases group 1 DUF563 PF04577.14 EMT50684.1 - 2.5e-50 171.5 0.0 3.2e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Methyltransf_11 PF08241.12 EMT50685.1 - 3.7e-19 69.2 0.0 5.7e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT50685.1 - 2.1e-18 66.8 0.0 3.1e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT50685.1 - 2.7e-17 63.1 0.0 3.3e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT50685.1 - 1e-16 61.1 0.0 1.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT50685.1 - 8.4e-14 52.1 0.0 1.4e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EMT50685.1 - 1.2e-05 24.1 0.0 1.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 EMT50685.1 - 4.5e-05 22.9 0.0 6.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 EMT50685.1 - 0.0017 17.3 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 EMT50685.1 - 0.0039 16.6 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EMT50685.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 EMT50685.1 - 0.023 14.0 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 EMT50685.1 - 0.037 13.6 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DREV PF05219.12 EMT50685.1 - 0.079 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase CheR PF01739.18 EMT50685.1 - 0.16 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_8 PF05148.15 EMT50685.1 - 0.17 11.7 0.0 0.66 9.8 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase DUF43 PF01861.16 EMT50686.1 - 1.1e-44 152.4 0.0 1.6e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain HTH_24 PF13412.6 EMT50686.1 - 0.012 15.2 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DnaJ_CXXCXGXG PF00684.19 EMT50686.1 - 0.037 14.4 1.5 0.078 13.3 1.5 1.5 1 0 0 1 1 1 0 DnaJ central domain Zn_Tnp_IS91 PF14319.6 EMT50686.1 - 0.15 12.1 1.5 0.35 10.9 1.5 1.6 1 1 0 1 1 1 0 Transposase zinc-binding domain PNP_UDP_1 PF01048.20 EMT50687.1 - 7.1e-18 64.7 4.0 8.2e-18 64.5 4.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily VitK2_biosynth PF02621.14 EMT50688.1 - 9.3e-85 284.3 0.0 1.1e-84 284.2 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis NMT1 PF09084.11 EMT50688.1 - 0.011 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like AP_endonuc_2 PF01261.24 EMT50689.1 - 5.2e-05 22.8 0.0 0.00049 19.6 0.0 2.1 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel Lac_bphage_repr PF06543.12 EMT50689.1 - 0.094 12.7 1.4 0.27 11.2 0.9 2.0 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor Mgr1 PF08602.10 EMT50690.1 - 0.033 13.0 0.1 0.044 12.6 0.1 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit AXE1 PF05448.12 EMT50691.1 - 5.3e-34 117.3 0.0 6.1e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Mrr_cat PF04471.12 EMT50692.1 - 2.8e-26 91.8 0.0 4.3e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Mrr_cat_2 PF13156.6 EMT50692.1 - 7.4e-07 29.1 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease MTES_1575 PF18741.1 EMT50692.1 - 0.0014 18.7 0.1 0.0036 17.5 0.1 1.7 1 0 0 1 1 1 1 REase_MTES_1575 DUF3519 PF12033.8 EMT50692.1 - 0.02 15.3 0.3 0.061 13.7 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) DUF4143 PF13635.6 EMT50692.1 - 0.048 13.8 0.1 0.099 12.8 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4143) ArsP_1 PF03773.13 EMT50692.1 - 0.052 12.7 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 Predicted permease DUF3929 PF13066.6 EMT50692.1 - 0.074 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) Sre PF03125.18 EMT50692.1 - 0.13 11.3 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor DUF2034 PF10356.9 EMT50692.1 - 1.8 7.9 5.4 13 5.1 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2034) NERD PF08378.11 EMT50693.1 - 1.6e-30 105.8 0.4 2.9e-30 104.9 0.4 1.4 1 0 0 1 1 1 1 Nuclease-related domain zf-C4_Topoisom PF01396.19 EMT50693.1 - 1.7e-16 59.7 4.4 2.9e-16 58.9 4.4 1.4 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger DUF1272 PF06906.11 EMT50693.1 - 0.012 15.7 0.3 0.022 14.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DNA_ligase_ZBD PF03119.16 EMT50693.1 - 0.051 13.6 1.3 0.15 12.1 1.3 1.8 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain ADK_lid PF05191.14 EMT50693.1 - 0.096 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid Swi6_N PF18530.1 EMT50693.1 - 0.13 12.4 1.6 7.6 6.7 0.8 2.9 2 1 0 2 2 2 0 Swi6 N-terminal domain ANT PF03374.14 EMT50694.1 - 3.9e-05 23.9 0.0 0.0034 17.7 0.0 2.3 2 0 0 2 2 2 1 Phage antirepressor protein KilAC domain IBD PF10416.9 EMT50694.1 - 0.0033 17.4 0.6 1 9.4 0.0 2.9 2 1 1 3 3 3 2 Transcription-initiator DNA-binding domain IBD RuvB_C PF05491.13 EMT50694.1 - 0.0045 16.8 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 1 RuvB C-terminal winged helix domain Transposase_24 PF03004.14 EMT50694.1 - 0.005 17.0 0.1 0.0098 16.0 0.1 1.5 1 0 0 1 1 1 1 Plant transposase (Ptta/En/Spm family) HTH_45 PF14947.6 EMT50694.1 - 0.014 15.4 0.1 0.3 11.1 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix Sin_N PF04801.13 EMT50694.1 - 0.075 12.2 0.3 11 5.1 0.1 2.3 1 1 0 2 2 2 0 Sin-like protein conserved region NUMOD1 PF07453.13 EMT50694.1 - 0.19 12.0 0.8 3.5 8.0 0.1 2.4 2 0 0 2 2 2 0 NUMOD1 domain Acetyltransf_3 PF13302.7 EMT50695.1 - 9.1e-25 87.9 0.0 1.2e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT50695.1 - 1.1e-12 48.4 0.0 1.2e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT50695.1 - 8.6e-09 35.7 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EMT50695.1 - 5.4e-06 26.1 0.0 9.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mfa1 PF17445.2 EMT50696.1 - 0.009 16.0 0.8 1.5 8.9 0.1 2.1 2 0 0 2 2 2 2 Mating factor A1 Acetyltransf_3 PF13302.7 EMT50697.1 - 1.1e-24 87.7 0.0 1.3e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT50697.1 - 1.6e-17 64.1 0.0 1.8e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT50697.1 - 4.3e-11 43.1 0.0 5.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EMT50697.1 - 3.7e-08 33.2 0.0 2.4e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT50697.1 - 7.5e-06 26.3 0.0 1.3e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT50697.1 - 1.9e-05 24.6 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT50697.1 - 0.025 14.5 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein TetR_C_17 PF17922.1 EMT50698.1 - 2e-36 124.1 0.4 4.2e-36 123.1 0.1 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EMT50698.1 - 9.2e-16 57.4 0.1 1.6e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 EMT50698.1 - 2.4e-06 27.7 0.8 3.9e-06 27.0 0.7 1.4 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase TetR_C_6 PF13977.6 EMT50698.1 - 0.00028 21.1 0.0 0.00097 19.3 0.0 1.8 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 EMT50698.1 - 0.0058 16.8 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain UPF0122 PF04297.14 EMT50698.1 - 0.069 13.4 0.3 0.13 12.5 0.3 1.5 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Y1_Tnp PF01797.16 EMT50699.1 - 1.5e-40 138.1 0.3 1.7e-40 137.9 0.3 1.0 1 0 0 1 1 1 1 Transposase IS200 like Peroxin-22 PF12827.7 EMT50699.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family OrfB_IS605 PF01385.19 EMT50700.1 - 6.2e-28 97.4 0.7 6.2e-28 97.4 0.7 1.8 2 0 0 2 2 2 1 Probable transposase OrfB_Zn_ribbon PF07282.11 EMT50700.1 - 1.8e-22 79.0 0.3 3.8e-22 78.0 0.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 EMT50700.1 - 5e-19 67.5 1.9 5e-19 67.5 1.9 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain DUF4127 PF13552.6 EMT50700.1 - 0.001 17.7 1.0 0.0019 16.9 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4127) zf-ISL3 PF14690.6 EMT50700.1 - 0.015 16.0 1.6 1.1 9.9 0.4 3.5 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 CpXC PF14353.6 EMT50700.1 - 0.018 15.1 0.6 0.087 12.9 0.0 2.3 2 0 0 2 2 2 0 CpXC protein TF_Zn_Ribbon PF08271.12 EMT50700.1 - 0.034 13.7 0.3 0.087 12.3 0.3 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 EMT50700.1 - 0.036 13.8 3.8 0.38 10.5 3.4 2.5 1 1 1 2 2 2 0 zinc-ribbon domain ING PF12998.7 EMT50700.1 - 0.24 12.0 0.1 0.24 12.0 0.1 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding zf-ribbon_3 PF13248.6 EMT50700.1 - 0.45 10.0 3.0 0.95 9.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-RanBP PF00641.18 EMT50700.1 - 7 6.1 6.8 0.82 9.1 0.7 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others HTH_18 PF12833.7 EMT50701.1 - 6.2e-24 84.1 0.1 7.6e-24 83.8 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EMT50701.1 - 4.9e-22 77.5 0.1 9.3e-11 41.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 EMT50701.1 - 0.0085 15.9 0.0 0.019 14.7 0.0 1.6 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 EMT50701.1 - 0.031 13.7 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Rrf2 PF02082.20 EMT50701.1 - 0.037 14.4 0.0 0.13 12.6 0.0 1.8 1 1 1 2 2 2 0 Transcriptional regulator HhH-GPD PF00730.25 EMT50702.1 - 1.3e-14 54.6 0.0 2.2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein OGG_N PF07934.12 EMT50702.1 - 2.7e-05 24.2 0.0 4.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain BsuBI_PstI_RE PF06616.11 EMT50702.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain DNA_binding_1 PF01035.20 EMT50703.1 - 4.9e-30 103.5 0.1 6.3e-30 103.1 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 EMT50703.1 - 0.0094 16.7 0.0 0.042 14.6 0.0 2.1 2 1 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain PAP2 PF01569.21 EMT50704.1 - 4.2e-16 59.0 6.7 4.2e-16 59.0 6.7 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EMT50704.1 - 5.1e-09 36.1 13.2 8.5e-08 32.1 13.2 2.0 1 1 0 1 1 1 1 PAP2 superfamily Phage_holin_2_4 PF16082.5 EMT50704.1 - 0.05 13.3 0.6 0.37 10.6 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF2645 PF10840.8 EMT50704.1 - 0.054 14.1 0.4 0.054 14.1 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) 7TM-7TMR_HD PF07698.11 EMT50704.1 - 0.14 11.9 9.5 1.2 8.8 9.4 2.1 1 1 0 1 1 1 0 7TM receptor with intracellular HD hydrolase CPP1-like PF11833.8 EMT50704.1 - 0.16 11.6 4.4 2.7 7.6 0.3 2.2 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PAP2_C PF14360.6 EMT50704.1 - 0.38 11.3 6.6 0.16 12.5 1.6 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal AHSA1 PF08327.11 EMT50705.1 - 4.1e-14 52.9 0.9 5.3e-14 52.5 0.9 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EMT50705.1 - 0.0055 17.0 0.1 0.008 16.5 0.1 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Peptidase_M3 PF01432.20 EMT50706.1 - 2.8e-37 129.1 0.2 5.1e-37 128.2 0.1 1.4 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M3_N PF08439.10 EMT50706.1 - 3.3e-20 72.1 0.2 1.1e-19 70.4 0.2 2.0 1 0 0 1 1 1 1 Oligopeptidase F NifW PF03206.14 EMT50706.1 - 0.18 12.3 1.2 25 5.4 0.4 3.1 3 0 0 3 3 3 0 Nitrogen fixation protein NifW 3-dmu-9_3-mt PF06983.13 EMT50707.1 - 1e-11 45.4 0.0 1.3e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyoxalase PF00903.25 EMT50707.1 - 3.2e-08 33.8 0.0 3.8e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3467 PF11950.8 EMT50707.1 - 0.039 14.1 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) TPR_19 PF14559.6 EMT50707.1 - 0.053 14.0 0.0 9.7 6.8 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4268 PF14088.6 EMT50707.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) TPR_8 PF13181.6 EMT50707.1 - 0.11 12.8 0.1 13 6.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase_6 PF18029.1 EMT50707.1 - 0.15 12.9 0.0 0.21 12.4 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Isochorismatase PF00857.20 EMT50708.1 - 3.3e-37 128.3 0.3 3.8e-37 128.1 0.3 1.0 1 0 0 1 1 1 1 Isochorismatase family CsgE PF10627.9 EMT50708.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Curli assembly protein CsgE HxlR PF01638.17 EMT50709.1 - 5.9e-23 80.5 0.6 7.2e-23 80.3 0.6 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_5 PF01022.20 EMT50709.1 - 1e-05 25.3 0.3 1.9e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_45 PF14947.6 EMT50709.1 - 0.0019 18.1 1.3 0.048 13.7 1.3 2.5 1 1 0 1 1 1 1 Winged helix-turn-helix HTH_20 PF12840.7 EMT50709.1 - 0.0042 17.1 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_33 PF13592.6 EMT50709.1 - 0.017 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Cdc6_C PF09079.11 EMT50709.1 - 0.042 13.8 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Replic_Relax PF13814.6 EMT50709.1 - 0.064 13.3 0.0 0.075 13.1 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation Methyltransf_31 PF13847.6 EMT50710.1 - 9.2e-23 80.7 0.0 1.2e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT50710.1 - 1.3e-16 61.1 0.0 2.2e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT50710.1 - 5e-15 55.9 0.0 7.9e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT50710.1 - 5.2e-13 49.2 0.0 8e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT50710.1 - 3.3e-12 47.0 0.0 5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT50710.1 - 1.8e-10 40.5 0.0 2.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EMT50710.1 - 4.9e-09 36.3 0.0 7.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 EMT50710.1 - 3.1e-08 33.5 0.0 4.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.19 EMT50710.1 - 1.4e-06 28.5 0.0 2.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EMT50710.1 - 3.4e-05 23.2 0.0 4.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EMT50710.1 - 0.00011 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EMT50710.1 - 0.00014 21.9 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EMT50710.1 - 0.0002 21.2 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.20 EMT50710.1 - 0.00071 18.7 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.11 EMT50710.1 - 0.00099 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 EMT50710.1 - 0.0012 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.20 EMT50710.1 - 0.0025 17.1 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EMT50710.1 - 0.0056 16.1 0.3 0.011 15.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EMT50710.1 - 0.016 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CheR PF01739.18 EMT50710.1 - 0.016 14.7 0.0 5.5 6.4 0.0 2.7 2 1 1 3 3 3 0 CheR methyltransferase, SAM binding domain TrkA_N PF02254.18 EMT50710.1 - 0.023 15.0 0.0 0.04 14.2 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain Methyltransf_19 PF04672.12 EMT50710.1 - 0.024 14.1 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl methyltransferase Methyltransf_4 PF02390.17 EMT50710.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MT0933_antitox PF14013.6 EMT50711.1 - 0.022 15.0 0.1 0.022 15.0 0.1 3.2 2 1 0 2 2 2 0 MT0933-like antitoxin protein Exo_endo_phos PF03372.23 EMT50712.1 - 2e-19 70.0 0.0 2.8e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EMT50712.1 - 0.00033 20.5 0.0 0.013 15.3 0.0 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF1462 PF07315.11 EMT50712.1 - 0.061 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Phosphodiest PF01663.22 EMT50713.1 - 1.5e-24 87.3 0.0 3e-24 86.3 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EMT50713.1 - 0.028 13.0 0.0 0.039 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF5500 PF17604.2 EMT50713.1 - 0.17 12.0 0.1 0.57 10.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5500) Peptidase_S41 PF03572.18 EMT50714.1 - 9.7e-43 145.6 0.0 1.7e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.6 EMT50714.1 - 5.9e-13 48.9 0.0 2e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EMT50714.1 - 7.1e-10 38.6 0.0 1.5e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EMT50714.1 - 3.5e-08 33.7 0.0 8.7e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EMT50714.1 - 0.0023 17.9 0.1 0.0078 16.2 0.0 1.9 2 0 0 2 2 2 1 Tricorn protease PDZ domain DUF1442 PF07279.11 EMT50714.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) SLH PF00395.20 EMT50715.1 - 2.6e-13 49.7 2.1 7.3e-07 29.1 0.0 3.8 4 0 0 4 4 4 2 S-layer homology domain TPR_19 PF14559.6 EMT50715.1 - 0.0071 16.8 2.4 0.024 15.1 2.4 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat NIF3 PF01784.18 EMT50716.1 - 1.5e-79 267.1 0.4 2.1e-79 266.6 0.4 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF1949 PF09186.11 EMT50716.1 - 0.069 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) TrmK PF04816.12 EMT50717.1 - 7.9e-65 218.2 0.1 9.3e-65 218.0 0.1 1.0 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_18 PF12847.7 EMT50717.1 - 3.5e-50 169.8 0.3 7.8e-50 168.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain N_Asn_amidohyd PF14736.6 EMT50717.1 - 0.0042 16.3 0.0 0.0068 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase AAR2 PF05282.11 EMT50717.1 - 0.047 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 AAR2 protein Acyl-CoA_dh_1 PF00441.24 EMT50718.1 - 1.2e-52 178.1 6.4 2.3e-52 177.2 6.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMT50718.1 - 1.6e-37 128.6 0.1 4.7e-37 127.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EMT50718.1 - 5.3e-26 90.7 0.1 9.9e-26 89.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EMT50718.1 - 8.9e-25 87.5 3.4 1.5e-24 86.7 3.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EMT50718.1 - 7.5e-05 22.5 0.7 0.001 18.8 0.0 2.3 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Sigma70_r3 PF04539.16 EMT50721.1 - 2.3e-31 107.7 2.3 2.3e-31 107.7 2.3 3.2 3 0 0 3 3 3 1 Sigma-70 region 3 Sigma70_r4 PF04545.16 EMT50721.1 - 1.1e-23 82.5 3.9 5.3e-20 70.7 1.7 2.9 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT50721.1 - 2.2e-22 78.6 0.3 4e-22 77.8 0.3 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r1_2 PF00140.20 EMT50721.1 - 3.7e-19 68.4 2.8 7.2e-19 67.5 0.7 2.5 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 Sigma70_r1_1 PF03979.14 EMT50721.1 - 2.6e-14 53.0 8.5 2.6e-14 53.0 8.5 2.8 3 1 0 3 3 3 1 Sigma-70 factor, region 1.1 Exonuc_VII_L PF02601.15 EMT50721.1 - 0.011 15.4 0.0 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit HTH_10 PF04967.12 EMT50721.1 - 0.011 15.5 0.1 1.6 8.6 0.1 2.8 2 1 0 2 2 2 0 HTH DNA binding domain tify PF06200.14 EMT50721.1 - 0.05 12.9 0.1 0.099 12.0 0.1 1.5 1 0 0 1 1 1 0 tify domain DUF2316 PF10078.9 EMT50721.1 - 0.07 13.4 0.8 0.65 10.3 0.1 2.9 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) Toprim_N PF08275.11 EMT50722.1 - 4.4e-44 149.6 0.0 1.1e-43 148.3 0.0 1.7 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 EMT50722.1 - 4.8e-39 132.1 0.0 1.5e-38 130.6 0.0 1.9 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_2 PF13155.6 EMT50722.1 - 2.1e-21 76.1 0.0 5e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 EMT50722.1 - 4.6e-15 55.9 0.1 1.4e-14 54.3 0.1 1.9 2 0 0 2 2 2 1 Toprim domain Toprim_3 PF13362.6 EMT50722.1 - 2.3e-11 43.9 0.1 9.3e-11 42.0 0.1 2.1 2 0 0 2 2 2 1 Toprim domain DnaB_bind PF10410.9 EMT50722.1 - 2.5e-09 37.2 0.3 2.5e-09 37.2 0.3 2.5 3 0 0 3 3 3 1 DnaB-helicase binding domain of primase Toprim PF01751.22 EMT50722.1 - 0.00062 20.0 0.0 0.0025 18.0 0.0 2.1 1 0 0 1 1 1 1 Toprim domain Thioredoxin_14 PF18402.1 EMT50722.1 - 0.032 14.2 0.5 0.21 11.5 0.1 2.3 2 1 0 3 3 3 0 Thioredoxin-like domain Peripla_BP_6 PF13458.6 EMT50722.1 - 0.035 13.8 0.2 0.063 12.9 0.2 1.3 1 0 0 1 1 1 0 Periplasmic binding protein DnaB PF00772.21 EMT50722.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain Kinase-PPPase PF03618.14 EMT50723.1 - 3e-102 341.8 0.0 3.4e-102 341.6 0.0 1.0 1 0 0 1 1 1 1 Kinase/pyrophosphorylase ANF_receptor PF01094.28 EMT50723.1 - 0.048 12.8 0.4 0.076 12.1 0.4 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region CBS PF00571.28 EMT50724.1 - 1.3e-15 57.6 0.1 5.5e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain HTH_11 PF08279.12 EMT50724.1 - 3.1e-13 49.4 0.0 6.6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_DeoR PF08220.12 EMT50724.1 - 8.5e-07 28.6 0.1 1.7e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR PF01047.22 EMT50724.1 - 0.00088 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EMT50724.1 - 0.0012 18.3 0.2 0.0023 17.5 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 EMT50724.1 - 0.0013 18.3 0.0 0.011 15.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_Mga PF08280.11 EMT50724.1 - 0.0039 17.2 0.0 0.0082 16.1 0.0 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Sigma70_r4 PF04545.16 EMT50724.1 - 0.0061 16.1 0.3 0.013 15.0 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 LexA_DNA_bind PF01726.16 EMT50724.1 - 0.03 14.1 0.2 0.099 12.4 0.2 1.8 1 1 0 1 1 1 0 LexA DNA binding domain HTH_7 PF02796.15 EMT50724.1 - 0.03 14.4 0.4 0.07 13.2 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Crp_2 PF13545.6 EMT50724.1 - 0.031 14.3 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_20 PF12840.7 EMT50724.1 - 0.037 14.1 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Put_DNA-bind_N PF06971.13 EMT50724.1 - 0.046 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Fe_dep_repress PF01325.19 EMT50724.1 - 0.057 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DprA_WH PF17782.1 EMT50724.1 - 0.068 13.3 0.1 0.2 11.8 0.1 1.7 2 0 0 2 2 2 0 DprA winged helix domain DUF3320 PF11784.8 EMT50724.1 - 0.083 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) Rrf2 PF02082.20 EMT50724.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator tRNA_synt_2f PF02092.17 EMT50725.1 - 5.4e-217 721.9 0.0 7e-217 721.6 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit DALR_1 PF05746.15 EMT50725.1 - 0.00017 21.7 0.4 0.00059 20.0 0.4 2.0 1 0 0 1 1 1 1 DALR anticodon binding domain Myb_DNA-bind_5 PF13873.6 EMT50725.1 - 0.14 12.3 0.7 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RAC_head PF16717.5 EMT50725.1 - 0.84 10.7 3.7 1.5 9.8 0.1 2.9 2 0 0 2 2 2 0 Ribosome-associated complex head domain tRNA-synt_2e PF02091.15 EMT50726.1 - 2.2e-152 506.1 0.1 2.5e-152 505.9 0.1 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit RecO_C PF02565.15 EMT50728.1 - 1.4e-41 141.9 0.4 1.7e-41 141.6 0.4 1.1 1 0 0 1 1 1 1 Recombination protein O C terminal RecO_N PF11967.8 EMT50728.1 - 6.3e-24 83.8 0.1 1.3e-23 82.8 0.0 1.6 2 0 0 2 2 2 1 Recombination protein O N terminal RecO_N_2 PF13114.6 EMT50728.1 - 6.1e-07 29.1 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 RecO N terminal ArfGap PF01412.18 EMT50728.1 - 0.036 14.1 0.1 0.069 13.2 0.1 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 EMT50728.1 - 0.1 12.8 0.5 0.21 11.7 0.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain YqzL PF14006.6 EMT50729.1 - 1.6e-14 53.9 0.1 1.8e-14 53.8 0.1 1.0 1 0 0 1 1 1 1 YqzL-like protein MMR_HSR1 PF01926.23 EMT50730.1 - 2.4e-25 88.8 0.3 4.2e-25 88.1 0.3 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 EMT50730.1 - 2.7e-20 72.0 3.1 5.7e-20 70.9 3.1 1.6 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 EMT50730.1 - 1.2e-15 57.4 0.3 1.7e-15 56.9 0.3 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EMT50730.1 - 1.8e-12 47.2 0.2 9.2e-11 41.6 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EMT50730.1 - 1.9e-11 44.3 0.7 5.9e-05 23.2 0.1 2.3 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 EMT50730.1 - 3.3e-08 33.6 1.3 3e-05 24.0 0.3 2.3 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EMT50730.1 - 1e-06 28.3 0.1 1.7e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 AIG1 family cobW PF02492.19 EMT50730.1 - 1.7e-06 27.8 1.4 0.00065 19.3 0.0 2.4 2 1 1 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1_Xtn PF16897.5 EMT50730.1 - 0.00014 21.8 0.0 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 EMT50730.1 - 0.00015 21.6 0.2 0.00043 20.1 0.2 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 EMT50730.1 - 0.00065 19.1 0.0 0.0009 18.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EMT50730.1 - 0.0012 19.1 0.1 0.01 16.1 0.1 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EMT50730.1 - 0.0022 17.4 0.1 0.0034 16.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NOG1 PF06858.14 EMT50730.1 - 0.0092 15.7 0.3 0.044 13.6 0.3 2.1 1 1 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) ABC_tran PF00005.27 EMT50730.1 - 0.018 15.5 0.3 0.063 13.8 0.1 2.0 2 1 0 2 2 2 0 ABC transporter SRP54 PF00448.22 EMT50730.1 - 0.019 14.6 0.1 0.036 13.7 0.1 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Lact-deh-memb PF09330.11 EMT50730.1 - 0.035 13.4 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding AAA_22 PF13401.6 EMT50730.1 - 0.042 14.1 0.0 0.13 12.6 0.0 1.8 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 EMT50730.1 - 0.042 13.0 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Arf PF00025.21 EMT50730.1 - 0.11 11.9 0.2 0.37 10.2 0.2 1.8 1 1 0 1 1 1 0 ADP-ribosylation factor family dCMP_cyt_deam_1 PF00383.23 EMT50731.1 - 6.1e-17 61.4 0.1 7.1e-17 61.1 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EMT50731.1 - 1.3e-11 44.8 0.5 5.1e-11 42.9 0.4 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EMT50731.1 - 0.011 15.4 1.7 0.28 10.7 0.5 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases DUF502 PF04367.13 EMT50732.1 - 3.5e-28 97.6 0.2 3.5e-28 97.6 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF502) DUF1866 PF08952.11 EMT50732.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) DAGK_prokar PF01219.19 EMT50733.1 - 7.1e-36 122.1 7.3 8.2e-36 121.9 7.3 1.0 1 0 0 1 1 1 1 Prokaryotic diacylglycerol kinase NrsF PF06532.11 EMT50733.1 - 0.00077 19.2 5.0 0.001 18.8 5.0 1.2 1 0 0 1 1 1 1 Negative regulator of sigma F DUF2892 PF11127.8 EMT50733.1 - 0.1 12.6 5.7 0.13 12.3 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) YiaAB PF05360.14 EMT50733.1 - 0.89 9.9 9.9 0.34 11.2 0.3 2.8 3 0 0 3 3 3 0 yiaA/B two helix domain UPF0054 PF02130.17 EMT50734.1 - 8.2e-49 164.7 0.5 9.6e-49 164.4 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 PhoH PF02562.16 EMT50735.1 - 4e-97 323.6 0.0 8.6e-97 322.5 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 EMT50735.1 - 2.6e-07 30.6 0.0 5.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMT50735.1 - 7.7e-06 26.3 0.2 3.7e-05 24.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EMT50735.1 - 9.6e-05 22.2 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.12 EMT50735.1 - 0.0023 17.6 0.0 0.52 9.9 0.0 2.2 2 0 0 2 2 2 2 Zonular occludens toxin (Zot) AAA_22 PF13401.6 EMT50735.1 - 0.0047 17.2 0.1 0.033 14.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMT50735.1 - 0.025 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EMT50735.1 - 0.07 12.9 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 EMT50735.1 - 0.077 12.5 0.9 1.7 8.1 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain YqfD PF06898.11 EMT50736.1 - 4.1e-121 404.4 4.1 4.6e-121 404.2 4.1 1.0 1 0 0 1 1 1 1 Putative stage IV sporulation protein YqfD DUF2922 PF11148.8 EMT50736.1 - 0.15 11.8 0.2 0.53 10.0 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) YabP PF07873.11 EMT50737.1 - 2.2e-18 65.8 0.3 2.8e-18 65.4 0.3 1.2 1 0 0 1 1 1 1 YabP family HTH_23 PF13384.6 EMT50738.1 - 0.00024 20.8 0.5 0.00034 20.3 0.5 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EMT50738.1 - 0.0077 15.9 0.0 0.0093 15.6 0.0 1.1 1 0 0 1 1 1 1 Sigma-70, region 4 Crp PF00325.20 EMT50738.1 - 0.015 14.9 0.0 0.038 13.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family HTH_28 PF13518.6 EMT50738.1 - 0.017 15.2 0.2 0.023 14.8 0.2 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 EMT50738.1 - 0.035 13.6 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Sigma-70, region 4 TnsD PF15978.5 EMT50738.1 - 0.054 12.5 0.2 0.059 12.4 0.2 1.0 1 0 0 1 1 1 0 Tn7-like transposition protein D YdfA_immunity PF12127.8 EMT50740.1 - 4.1e-165 548.4 17.5 4.9e-165 548.2 17.5 1.0 1 0 0 1 1 1 1 SigmaW regulon antibacterial Seryl_tRNA_N PF02403.22 EMT50740.1 - 0.00018 21.7 4.2 0.00041 20.6 4.2 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain FtsH_ext PF06480.15 EMT50740.1 - 0.11 12.9 0.0 0.29 11.5 0.0 1.9 1 1 0 1 1 1 0 FtsH Extracellular NfeD PF01957.18 EMT50741.1 - 2.2e-13 50.4 1.5 8.2e-13 48.5 1.5 2.0 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding SDH_sah PF01972.16 EMT50741.1 - 3.6e-07 29.5 0.2 6.5e-07 28.6 0.2 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.23 EMT50741.1 - 1.4e-05 25.1 0.9 1.4e-05 25.1 0.9 1.9 2 1 0 2 2 2 1 Clp protease Peptidase_S49 PF01343.18 EMT50741.1 - 0.00031 20.7 0.2 0.00031 20.7 0.2 2.9 3 0 0 3 3 3 1 Peptidase family S49 YqeY PF09424.10 EMT50742.1 - 3.1e-55 186.2 9.5 3.4e-55 186.0 9.5 1.0 1 0 0 1 1 1 1 Yqey-like protein GatB_Yqey PF02637.18 EMT50742.1 - 6.3e-05 22.9 1.2 6.3e-05 22.9 1.2 1.9 1 1 0 1 1 1 1 GatB domain Ribosomal_S21 PF01165.20 EMT50743.1 - 4.2e-21 74.4 11.8 4.5e-21 74.3 11.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S21 HIT PF01230.23 EMT50744.1 - 4.8e-26 91.4 0.5 5.4e-26 91.2 0.5 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EMT50744.1 - 6.6e-23 81.4 1.2 7e-23 81.3 1.2 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Mur_ligase_M PF08245.12 EMT50745.1 - 1.9e-45 155.3 0.0 2.9e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EMT50745.1 - 7.1e-15 55.0 0.0 4.3e-14 52.5 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 EMT50745.1 - 2.4e-07 31.0 0.0 5.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, catalytic domain SDH_alpha PF03313.15 EMT50745.1 - 0.034 13.8 0.1 0.062 13.0 0.1 1.4 1 0 0 1 1 1 0 Serine dehydratase alpha chain DPPIV_N PF00930.21 EMT50746.1 - 0.00072 18.4 0.2 0.2 10.4 0.2 3.7 2 1 0 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region ANAPC4_WD40 PF12894.7 EMT50746.1 - 0.12 12.7 0.0 25 5.2 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Dala_Dala_lig_C PF07478.13 EMT50747.1 - 1.3e-76 256.7 0.0 1.6e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 EMT50747.1 - 1.3e-30 105.9 0.0 3.1e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 EMT50747.1 - 2.9e-12 46.5 0.2 4.6e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EMT50747.1 - 3.2e-08 33.3 0.2 6.1e-08 32.4 0.2 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 EMT50747.1 - 9.4e-06 25.8 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EMT50747.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EMT50747.1 - 0.0027 17.3 0.0 0.008 15.8 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain MCR_beta_N PF02783.15 EMT50747.1 - 0.065 12.9 0.0 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Amidase_5 PF05382.13 EMT50748.1 - 0.062 13.2 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase DUF4177 PF13783.6 EMT50749.1 - 2.2e-16 59.9 0.0 2.4e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4177) BTRD1 PF17660.1 EMT50749.1 - 0.0018 18.0 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial tandem repeat domain 1 PUA_3 PF17785.1 EMT50750.1 - 5.4e-22 77.4 0.0 1.1e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain Methyltrans_SAM PF10672.9 EMT50750.1 - 4.7e-20 71.9 0.0 3.2e-13 49.5 0.0 2.3 2 0 0 2 2 2 2 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 EMT50750.1 - 8.4e-10 38.6 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 EMT50750.1 - 1.5e-08 34.6 0.0 3.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT50750.1 - 8.3e-08 32.8 0.0 1.7e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMT50750.1 - 5.8e-06 25.9 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PUA PF01472.20 EMT50750.1 - 8.8e-06 25.6 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 PUA domain Met_10 PF02475.16 EMT50750.1 - 2.5e-05 24.1 0.0 0.0032 17.3 0.0 2.3 2 0 0 2 2 2 1 Met-10+ like-protein TRM PF02005.16 EMT50750.1 - 5e-05 22.6 0.0 6.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.10 EMT50750.1 - 0.00053 19.6 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 EMT50750.1 - 0.00065 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EMT50750.1 - 0.0016 19.0 0.2 0.0042 17.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.18 EMT50750.1 - 0.015 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 EMT50750.1 - 0.015 16.0 0.0 0.036 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EMT50750.1 - 0.016 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0113 PF03657.13 EMT50750.1 - 0.075 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 UPF0113 PUA domain tRNA_U5-meth_tr PF05958.11 EMT50750.1 - 0.11 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF4388 PF14332.6 EMT50750.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4388) Na_Pi_cotrans PF02690.15 EMT50751.1 - 2.1e-58 196.3 28.7 4.2e-40 137.1 10.0 2.1 1 1 1 2 2 2 2 Na+/Pi-cotransporter DUF2127 PF09900.9 EMT50751.1 - 0.87 9.8 14.5 0.12 12.6 1.5 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2127) DPM2 PF07297.12 EMT50751.1 - 7.6 6.9 6.8 1.5 9.2 0.1 3.2 4 0 0 4 4 4 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) LrgB PF04172.16 EMT50752.1 - 1.2e-60 204.7 15.7 1.4e-60 204.5 15.7 1.0 1 0 0 1 1 1 1 LrgB-like family NiFe_hyd_3_EhaA PF17367.2 EMT50752.1 - 1.6 9.0 12.5 0.56 10.4 2.9 2.7 3 0 0 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A LrgA PF03788.14 EMT50753.1 - 1.6e-26 92.1 10.1 1.6e-26 92.1 10.1 1.3 2 0 0 2 2 2 1 LrgA family 2HCT PF03390.15 EMT50753.1 - 0.00044 19.0 6.5 0.00052 18.8 6.5 1.0 1 0 0 1 1 1 1 2-hydroxycarboxylate transporter family NADH_oxidored PF08040.11 EMT50753.1 - 0.095 12.4 0.5 2 8.2 0.0 2.7 3 0 0 3 3 3 0 MNLL subunit DUF2070 PF09843.9 EMT50753.1 - 0.34 9.1 2.2 0.39 9.0 2.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DeoC PF01791.9 EMT50754.1 - 9.1e-23 81.1 5.5 1e-22 80.9 5.5 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase IMPDH PF00478.25 EMT50754.1 - 0.012 14.7 2.4 0.013 14.5 2.4 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 EMT50754.1 - 0.029 13.6 2.2 0.058 12.6 2.2 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Sacchrp_dh_NADP PF03435.18 EMT50754.1 - 0.042 14.1 0.6 0.18 12.0 0.3 2.2 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NUDIX PF00293.28 EMT50755.1 - 5.3e-16 58.9 0.4 5.7e-16 58.8 0.4 1.0 1 0 0 1 1 1 1 NUDIX domain Arm-DNA-bind_1 PF09003.10 EMT50755.1 - 0.056 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage lambda integrase, Arm DNA-binding domain Radical_SAM PF04055.21 EMT50756.1 - 6.5e-27 94.9 0.4 1.9e-26 93.4 0.1 2.0 3 0 0 3 3 3 1 Radical SAM superfamily UPF0004 PF00919.20 EMT50756.1 - 1.6e-26 92.2 0.0 3.7e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 EMT50756.1 - 0.00016 21.6 0.0 0.00034 20.5 0.0 1.6 1 0 0 1 1 1 1 TRAM domain B12-binding PF02310.19 EMT50756.1 - 0.0053 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain DUF4862 PF16154.5 EMT50756.1 - 0.19 11.1 0.0 0.38 10.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4862) Methyltrans_RNA PF04452.14 EMT50757.1 - 6.3e-75 251.4 0.1 7.1e-75 251.2 0.1 1.0 1 0 0 1 1 1 1 RNA methyltransferase PrmA PF06325.13 EMT50758.1 - 9.8e-103 343.6 0.4 1.1e-102 343.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EMT50758.1 - 5.5e-11 42.3 0.4 2.5e-10 40.2 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EMT50758.1 - 1.9e-10 40.8 0.1 3.7e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT50758.1 - 5.8e-10 39.7 0.1 2.1e-09 38.0 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT50758.1 - 3.4e-08 33.4 0.1 6.6e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT50758.1 - 1.2e-07 32.3 0.1 3.7e-07 30.7 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EMT50758.1 - 1.2e-06 28.1 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EMT50758.1 - 3.4e-06 27.7 0.1 3.7e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 EMT50758.1 - 2.5e-05 24.1 0.1 4.1e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 EMT50758.1 - 0.00054 19.8 0.0 0.014 15.2 0.0 2.6 2 1 0 3 3 3 1 Methyltransferase domain TrmK PF04816.12 EMT50758.1 - 0.0032 17.0 0.5 0.0065 16.0 0.5 1.5 1 1 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase UPF0020 PF01170.18 EMT50758.1 - 0.0037 17.0 0.1 0.0063 16.2 0.1 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 EMT50758.1 - 0.0054 16.4 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 RrnaAD PF00398.20 EMT50758.1 - 0.024 13.7 0.0 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EMT50758.1 - 0.053 13.3 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EMT50758.1 - 0.054 13.2 0.5 0.091 12.5 0.1 1.5 2 0 0 2 2 2 0 Lysine methyltransferase Transket_pyr PF02779.24 EMT50758.1 - 0.065 12.9 0.0 0.5 10.0 0.0 2.1 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain N6_N4_Mtase PF01555.18 EMT50758.1 - 0.085 12.5 0.0 8 6.1 0.0 2.1 2 0 0 2 2 2 0 DNA methylase GCD14 PF08704.10 EMT50758.1 - 0.087 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DnaJ_C PF01556.18 EMT50759.1 - 1e-42 145.7 0.0 1.8e-42 144.9 0.0 1.4 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMT50759.1 - 5.7e-27 93.6 5.5 1.3e-26 92.4 5.5 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EMT50759.1 - 6.2e-14 52.1 18.8 1.1e-13 51.3 18.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EMT50759.1 - 0.0054 16.7 17.4 0.19 11.7 4.1 3.4 1 1 2 3 3 3 3 Tryptophan RNA-binding attenuator protein inhibitory protein Rubredoxin PF00301.20 EMT50759.1 - 0.026 14.5 3.3 0.044 13.8 0.5 2.7 3 0 0 3 3 3 0 Rubredoxin PaaX_C PF08223.11 EMT50759.1 - 0.18 12.1 0.7 2 8.7 0.2 2.1 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain DUF5351 PF17302.2 EMT50759.1 - 0.61 10.3 26.9 0.25 11.6 4.6 4.5 4 0 0 4 4 4 0 Family of unknown function (DUF5351) zf-RING_10 PF16685.5 EMT50759.1 - 2.8 8.1 8.1 2.4 8.3 5.7 2.0 1 1 1 2 2 2 0 zinc RING finger of MSL2 TackOD1 PF18551.1 EMT50759.1 - 4.9 6.8 8.3 1.4 8.5 1.5 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Cytochrom_c3_2 PF14537.6 EMT50759.1 - 9.2 6.8 10.0 55 4.3 10.1 2.1 1 1 1 2 2 2 0 Cytochrome c3 HSP70 PF00012.20 EMT50760.1 - 1.4e-255 849.2 21.1 8.3e-224 744.2 15.4 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EMT50760.1 - 5.3e-21 74.8 2.4 5.3e-21 74.8 2.4 2.6 2 2 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EMT50760.1 - 0.005 16.6 0.1 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EMT50760.1 - 0.38 11.2 7.3 0.58 10.6 0.9 3.7 2 1 0 2 2 2 0 Cell division protein FtsA hDGE_amylase PF14701.6 EMT50760.1 - 1.4 7.9 5.3 2.3 7.2 5.3 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF1664 PF07889.12 EMT50760.1 - 2.8 8.0 7.1 1.1 9.3 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GrpE PF01025.19 EMT50761.1 - 2e-56 190.2 3.7 2.4e-56 189.9 3.7 1.1 1 0 0 1 1 1 1 GrpE GST_C_3 PF14497.6 EMT50761.1 - 0.03 14.5 0.2 0.064 13.5 0.1 1.7 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain CoA_transf_3 PF02515.17 EMT50761.1 - 0.041 13.0 1.8 0.05 12.7 1.8 1.1 1 0 0 1 1 1 0 CoA-transferase family III DDRGK PF09756.9 EMT50761.1 - 0.074 12.6 8.4 0.09 12.4 8.4 1.2 1 0 0 1 1 1 0 DDRGK domain PEPcase PF00311.17 EMT50761.1 - 0.14 10.2 4.2 0.17 9.9 4.2 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Uso1_p115_C PF04871.13 EMT50761.1 - 0.28 11.6 11.7 0.5 10.7 11.7 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region MIF4G_like_2 PF09090.11 EMT50761.1 - 0.73 9.3 6.1 0.94 8.9 6.1 1.1 1 0 0 1 1 1 0 MIF4G like Alanine_zipper PF11839.8 EMT50761.1 - 1.6 9.1 10.6 0.63 10.4 7.9 1.7 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Mitoc_mL59 PF18126.1 EMT50761.1 - 4.5 7.6 7.1 7.8 6.8 0.1 2.7 1 1 2 3 3 3 0 Mitochondrial ribosomal protein mL59 HrcA PF01628.21 EMT50762.1 - 8e-68 228.6 1.0 1e-67 228.3 1.0 1.1 1 0 0 1 1 1 1 HrcA protein C terminal domain HrcA_DNA-bdg PF03444.15 EMT50762.1 - 1.6e-05 24.5 0.2 6.5e-05 22.5 0.0 2.2 3 0 0 3 3 3 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding LexA_DNA_bind PF01726.16 EMT50762.1 - 0.033 14.0 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 LexA DNA binding domain HTH_11 PF08279.12 EMT50762.1 - 0.067 13.2 0.1 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 HTH domain Radical_SAM PF04055.21 EMT50763.1 - 3.9e-27 95.7 0.0 5.5e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 EMT50763.1 - 1e-16 60.7 0.3 3.7e-16 58.9 0.3 2.1 1 0 0 1 1 1 1 HemN C-terminal domain SelB-wing_2 PF09106.11 EMT50763.1 - 0.065 13.4 0.1 0.2 11.9 0.1 1.9 1 0 0 1 1 1 0 Elongation factor SelB, winged helix GTP_EFTU PF00009.27 EMT50764.1 - 5.9e-55 185.8 0.1 8.8e-55 185.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EMT50764.1 - 1.8e-53 179.2 0.6 3.4e-53 178.3 0.6 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EMT50764.1 - 1.5e-25 89.0 0.0 3.8e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMT50764.1 - 3.9e-13 49.6 3.4 3.9e-13 49.6 3.4 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EMT50764.1 - 7.3e-07 29.2 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EMT50764.1 - 9.1e-05 22.5 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 EMT50764.1 - 0.00058 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ras PF00071.22 EMT50764.1 - 0.0008 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.9 EMT50764.1 - 0.0038 17.0 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EMT50764.1 - 0.036 13.5 0.0 0.084 12.3 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Sigma70_r4_2 PF08281.12 EMT50766.1 - 4.4e-18 64.7 0.4 8.1e-18 63.8 0.4 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT50766.1 - 4.9e-14 51.8 0.1 1e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EMT50766.1 - 8.1e-12 44.5 0.2 1.4e-11 43.7 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT50766.1 - 1.3e-05 25.2 0.6 2.2e-05 24.5 0.1 1.6 2 0 0 2 2 2 1 ECF sigma factor HTH_AsnC-type PF13404.6 EMT50766.1 - 0.00012 21.9 1.1 0.00023 20.9 0.1 2.1 3 0 0 3 3 2 1 AsnC-type helix-turn-helix domain HTH_30 PF13556.6 EMT50766.1 - 0.00019 21.2 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 EMT50766.1 - 0.00024 21.1 0.3 0.00064 19.8 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EMT50766.1 - 0.00045 19.6 0.1 0.00093 18.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 EMT50766.1 - 0.00066 19.6 0.2 0.0014 18.6 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 EMT50766.1 - 0.00083 19.1 0.1 0.0026 17.5 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Mga PF08280.11 EMT50766.1 - 0.0027 17.7 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_DeoR PF08220.12 EMT50766.1 - 0.0054 16.4 0.2 0.071 12.9 0.0 2.7 3 0 0 3 3 3 1 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 EMT50766.1 - 0.0058 16.2 0.0 0.018 14.6 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_17 PF12728.7 EMT50766.1 - 0.013 15.7 0.9 0.032 14.4 0.1 2.1 3 0 0 3 3 2 0 Helix-turn-helix domain Phage_antitermQ PF06530.12 EMT50766.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.5 2 0 0 2 2 1 0 Phage antitermination protein Q UPF0122 PF04297.14 EMT50766.1 - 0.025 14.8 0.0 0.098 12.9 0.0 1.8 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like DUF746 PF05344.11 EMT50766.1 - 0.026 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) DUF4567 PF15131.6 EMT50766.1 - 0.049 13.7 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) HTH_38 PF13936.6 EMT50766.1 - 0.051 13.3 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MerR_1 PF13411.6 EMT50766.1 - 0.078 13.1 0.1 0.22 11.6 0.1 1.8 1 1 0 1 1 1 0 MerR HTH family regulatory protein MerR PF00376.23 EMT50766.1 - 0.093 12.5 0.2 0.28 11.0 0.2 1.8 2 0 0 2 2 1 0 MerR family regulatory protein DUF134 PF02001.16 EMT50766.1 - 0.11 13.1 0.1 0.24 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF134 HTH_7 PF02796.15 EMT50766.1 - 0.11 12.6 0.1 0.4 10.8 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain of resolvase TnsD PF15978.5 EMT50766.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.5 2 0 0 2 2 2 0 Tn7-like transposition protein D Methyltransf_25 PF13649.6 EMT50767.1 - 1.8e-12 47.8 0.0 2.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT50767.1 - 8.9e-11 42.3 0.0 1.3e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT50767.1 - 8.8e-09 36.0 0.0 1.3e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rubredoxin PF00301.20 EMT50767.1 - 1.2e-08 34.8 0.3 3e-08 33.5 0.3 1.7 1 0 0 1 1 1 1 Rubredoxin Methyltransf_23 PF13489.6 EMT50767.1 - 1.1e-07 31.8 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT50767.1 - 1.7e-07 31.2 0.0 2.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT50767.1 - 0.029 13.7 0.0 0.06 12.7 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Rubredoxin_2 PF18073.1 EMT50767.1 - 0.052 13.3 5.5 0.086 12.6 0.6 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain VATC PF18716.1 EMT50767.1 - 0.073 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Vms1-associating treble clef domain EcoEI_R_C PF08463.10 EMT50767.1 - 0.13 12.4 0.5 0.47 10.5 0.1 1.9 1 1 1 2 2 2 0 EcoEI R protein C-terminal Methyltransf_32 PF13679.6 EMT50767.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.12 EMT50767.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein ABC_tran PF00005.27 EMT50768.1 - 1.5e-33 116.2 0.0 2.2e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT50768.1 - 7.8e-12 45.6 1.1 7.4e-06 26.0 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT50768.1 - 1.5e-07 31.1 0.5 7.7e-07 28.8 0.5 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT50768.1 - 3.2e-05 23.8 0.0 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EMT50768.1 - 0.00031 20.4 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT50768.1 - 0.002 18.5 0.1 0.0036 17.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EMT50768.1 - 0.0039 16.4 0.2 0.015 14.5 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 EMT50768.1 - 0.004 17.3 0.0 0.0096 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMT50768.1 - 0.0059 17.1 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 EMT50768.1 - 0.0071 16.6 0.1 0.095 13.0 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 EMT50768.1 - 0.0094 15.9 0.4 0.19 11.6 0.0 2.6 2 1 1 3 3 3 1 NACHT domain AAA_30 PF13604.6 EMT50768.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EMT50768.1 - 0.016 15.3 0.0 0.15 12.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 EMT50768.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EMT50768.1 - 0.029 14.6 2.3 0.39 11.0 2.3 2.2 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EMT50768.1 - 0.031 13.5 0.0 0.031 13.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 EMT50768.1 - 0.051 12.8 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 EMT50768.1 - 0.059 13.3 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 EMT50768.1 - 0.076 13.4 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EMT50768.1 - 0.077 13.3 0.1 0.16 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain RNA12 PF10443.9 EMT50768.1 - 0.084 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein AAA_24 PF13479.6 EMT50768.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain FecCD PF01032.18 EMT50769.1 - 5.4e-98 327.8 35.9 6.5e-98 327.6 35.9 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 EMT50769.1 - 0.0032 17.0 20.2 0.0032 17.0 20.2 2.0 2 1 0 2 2 2 1 ABC 3 transport family Peripla_BP_2 PF01497.18 EMT50770.1 - 2.7e-31 109.0 0.5 3.6e-31 108.6 0.5 1.1 1 0 0 1 1 1 1 Periplasmic binding protein DUF3155 PF11352.8 EMT50770.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) Peptidase_M24 PF00557.24 EMT50771.1 - 5.5e-69 232.0 0.3 7e-69 231.7 0.3 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EMT50771.1 - 4.1e-28 98.6 0.0 1e-27 97.3 0.0 1.7 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Abhydrolase_1 PF00561.20 EMT50772.1 - 4.9e-22 78.8 0.5 1e-15 58.1 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMT50772.1 - 2.2e-15 56.6 0.6 3.4e-15 56.0 0.6 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMT50772.1 - 5.4e-13 50.1 1.0 7.2e-13 49.6 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EMT50772.1 - 7.4e-09 34.7 0.0 9e-09 34.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 EMT50772.1 - 2.3e-07 30.8 0.1 1.9e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EMT50772.1 - 0.00071 19.1 0.5 0.081 12.4 0.5 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EMT50772.1 - 0.0041 16.7 0.0 1.6 8.2 0.1 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.13 EMT50772.1 - 0.006 16.3 0.3 0.044 13.5 0.3 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EMT50772.1 - 0.0082 16.0 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EMT50772.1 - 0.011 15.9 1.0 0.034 14.2 0.2 1.9 2 0 0 2 2 2 0 Thioesterase domain Esterase PF00756.20 EMT50772.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 EMT50772.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase BAAT_C PF08840.11 EMT50772.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.13 EMT50772.1 - 0.024 14.5 1.1 0.19 11.6 0.3 2.4 1 1 1 2 2 2 0 Serine hydrolase Peptidase_S15 PF02129.18 EMT50772.1 - 0.033 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 EMT50772.1 - 0.042 14.0 0.1 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein VirJ PF06057.11 EMT50772.1 - 0.044 13.6 0.0 0.38 10.6 0.0 2.1 2 1 0 2 2 2 0 Bacterial virulence protein (VirJ) DUF3530 PF12048.8 EMT50772.1 - 0.046 13.1 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Cutinase PF01083.22 EMT50772.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase BPD_transp_1 PF00528.22 EMT50773.1 - 1.6e-32 112.7 7.3 1.6e-32 112.7 7.3 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT50773.1 - 1e-18 67.0 0.3 1e-18 67.0 0.3 3.2 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C DUF3593 PF12159.8 EMT50773.1 - 0.016 15.2 0.3 0.063 13.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) Cation_ATPase_C PF00689.21 EMT50773.1 - 0.13 12.0 4.4 2.8 7.6 0.0 3.3 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Wzz PF02706.15 EMT50773.1 - 0.32 11.3 0.0 0.32 11.3 0.0 2.5 3 0 0 3 3 3 0 Chain length determinant protein BPD_transp_1 PF00528.22 EMT50774.1 - 8.1e-45 152.8 8.8 8.1e-45 152.8 8.8 2.0 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3561 PF12084.8 EMT50774.1 - 0.085 12.9 0.2 0.085 12.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3561) DUF4022 PF13214.6 EMT50774.1 - 0.18 12.1 0.3 0.18 12.1 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4022) DUF2157 PF09925.9 EMT50774.1 - 0.5 10.2 5.3 5.9 6.7 0.0 3.3 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) SBP_bac_5 PF00496.22 EMT50775.1 - 7.8e-123 410.2 4.1 9.9e-123 409.8 4.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF2786 PF10979.8 EMT50775.1 - 0.081 12.9 0.1 0.27 11.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) DUF3558 PF12079.8 EMT50775.1 - 0.14 12.1 1.2 0.23 11.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) ABC_tran PF00005.27 EMT50776.1 - 1.2e-32 113.3 0.0 1.6e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT50776.1 - 1.8e-18 66.8 0.4 3.2e-18 66.0 0.4 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_16 PF13191.6 EMT50776.1 - 0.002 18.5 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EMT50776.1 - 0.0064 16.3 0.7 0.16 11.7 0.1 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 EMT50776.1 - 0.03 14.0 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 EMT50776.1 - 0.042 14.1 0.5 0.11 12.7 0.5 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMT50776.1 - 0.11 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EMT50776.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 EMT50776.1 - 0.16 11.3 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 AIG1 family Mg_chelatase PF01078.21 EMT50776.1 - 0.16 11.3 0.0 0.72 9.2 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 EMT50776.1 - 0.19 11.6 0.1 0.33 10.9 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 EMT50776.1 - 0.21 11.6 0.1 0.41 10.7 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_13 PF13166.6 EMT50776.1 - 0.27 9.8 0.0 0.4 9.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMT50777.1 - 1.3e-27 97.0 0.0 1.8e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT50777.1 - 8.5e-20 71.0 0.0 1.6e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT50777.1 - 0.00014 21.8 0.2 0.00033 20.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT50777.1 - 0.00015 21.3 0.0 0.00034 20.1 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.25 EMT50777.1 - 0.091 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 EMT50777.1 - 0.13 12.6 0.7 2.2 8.5 0.2 2.1 2 0 0 2 2 2 0 AAA domain DUF3679 PF12438.8 EMT50778.1 - 5.4e-17 61.2 0.2 7.3e-17 60.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3679) SpoIIP PF07454.11 EMT50779.1 - 4.7e-65 219.7 0.1 5.6e-65 219.4 0.1 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DUF3123 PF11321.8 EMT50779.1 - 0.18 12.5 0.7 0.38 11.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) ptaRNA1_toxin PF12703.7 EMT50779.1 - 0.92 9.6 3.0 4.2 7.5 0.1 2.9 3 0 0 3 3 3 0 Toxin of toxin-antitoxin type 1 system Peptidase_A25 PF03418.14 EMT50780.1 - 3.5e-166 552.5 0.8 4e-166 552.3 0.8 1.0 1 0 0 1 1 1 1 Germination protease DUF1256 PF06866.11 EMT50780.1 - 9.7e-05 21.8 0.1 0.39 10.1 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1256) DNA_pol_B_thumb PF14791.6 EMT50780.1 - 0.016 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta thumb Ribosomal_S20p PF01649.18 EMT50781.1 - 1.1e-26 93.2 15.2 1.3e-26 93.1 15.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 PPR_long PF17177.4 EMT50781.1 - 0.017 14.5 0.7 0.018 14.4 0.7 1.0 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP C-C_Bond_Lyase PF15617.6 EMT50781.1 - 0.028 13.6 0.4 0.03 13.5 0.4 1.1 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold DNA_pol3_delta PF06144.13 EMT50782.1 - 5e-35 120.8 0.0 8e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delta2 PF13177.6 EMT50782.1 - 0.031 14.1 0.0 0.18 11.6 0.0 2.2 1 1 1 2 2 2 0 DNA polymerase III, delta subunit TPR_14 PF13428.6 EMT50782.1 - 0.57 11.1 0.1 0.57 11.1 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-HC2 PF13490.6 EMT50783.1 - 0.015 15.6 0.2 0.029 14.6 0.2 1.5 1 0 0 1 1 1 0 Putative zinc-finger CDC27 PF09507.10 EMT50783.1 - 0.034 13.5 31.6 0.056 12.8 31.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ECM1 PF05782.11 EMT50783.1 - 0.88 8.4 19.8 1.2 7.9 19.8 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Sigma70_r4_2 PF08281.12 EMT50784.1 - 8.6e-21 73.4 0.2 1.9e-20 72.3 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT50784.1 - 2.1e-14 53.0 0.3 4.2e-14 52.1 0.3 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EMT50784.1 - 6.1e-12 44.9 0.1 1.1e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT50784.1 - 7.2e-07 29.3 1.1 2.2e-06 27.7 1.1 1.7 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 EMT50784.1 - 0.0009 19.0 0.0 0.0044 16.8 0.0 2.2 1 1 0 1 1 1 1 Homeodomain-like domain UPF0122 PF04297.14 EMT50784.1 - 0.0035 17.5 0.8 0.01 16.0 0.2 2.0 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_16 PF12645.7 EMT50784.1 - 0.0041 17.1 0.9 0.012 15.6 0.3 2.2 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_40 PF14493.6 EMT50784.1 - 0.011 16.1 0.1 0.09 13.2 0.0 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 EMT50784.1 - 0.012 15.7 0.0 0.86 9.8 0.0 2.6 1 1 1 2 2 2 0 Helix-turn-helix domain GerE PF00196.19 EMT50784.1 - 0.012 15.1 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF2795 PF11387.8 EMT50784.1 - 0.064 13.5 0.8 0.72 10.1 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2795) Terminase_5 PF06056.12 EMT50784.1 - 0.069 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Competence PF03772.16 EMT50785.1 - 3.4e-59 200.4 30.5 3.4e-59 200.4 30.5 1.7 2 0 0 2 2 2 1 Competence protein DUF4131 PF13567.6 EMT50785.1 - 6.5e-23 81.2 0.0 6.5e-23 81.2 0.0 4.2 4 1 0 4 4 4 2 Domain of unknown function (DUF4131) Lactamase_B PF00753.27 EMT50785.1 - 3.5e-21 76.1 2.1 1.1e-20 74.5 1.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMT50785.1 - 0.00082 18.9 0.0 0.0018 17.8 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain YlaH PF14036.6 EMT50785.1 - 0.17 12.2 3.6 0.21 11.9 0.6 2.4 2 0 0 2 2 2 0 YlaH-like protein Asn_synthase PF00733.21 EMT50786.1 - 2.3e-102 343.3 0.3 3e-102 342.9 0.3 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EMT50786.1 - 3.9e-42 143.1 0.0 7e-42 142.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EMT50786.1 - 9.1e-35 119.8 0.0 1.5e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EMT50786.1 - 4e-05 23.2 0.0 9.7e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 Aluminium induced protein HHH_3 PF12836.7 EMT50787.1 - 1.2e-23 83.1 0.0 1.9e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif SLBB PF10531.9 EMT50787.1 - 5.4e-14 51.8 0.0 1.2e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 SLBB domain HHH PF00633.23 EMT50787.1 - 8.7e-14 50.6 0.0 1.7e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.6 EMT50787.1 - 8.3e-07 29.5 0.2 6.5e-06 26.7 0.2 2.4 1 1 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EMT50787.1 - 0.0012 18.9 0.0 0.071 13.2 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif T2SSK PF03934.13 EMT50787.1 - 0.0017 17.8 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_8 PF14716.6 EMT50787.1 - 0.014 15.7 0.1 3.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain HRDC PF00570.23 EMT50787.1 - 0.04 13.9 0.0 7.6 6.6 0.0 2.6 3 0 0 3 3 3 0 HRDC domain Serglycin PF04360.12 EMT50787.1 - 0.048 13.6 0.3 0.048 13.6 0.3 2.4 2 1 0 2 2 1 0 Serglycin FixQ PF05545.11 EMT50787.1 - 0.055 13.4 0.1 0.16 12.0 0.2 1.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ HHH_6 PF14579.6 EMT50787.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF655 PF04919.12 EMT50787.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF655) Cdd1 PF11731.8 EMT50787.1 - 0.19 12.0 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Pathogenicity locus F420_oxidored PF03807.17 EMT50788.1 - 2e-17 63.5 0.1 4e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent P5CR_dimer PF14748.6 EMT50788.1 - 2.2e-17 63.2 0.0 5.1e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation NAD_binding_2 PF03446.15 EMT50788.1 - 1.8e-07 31.5 0.0 2.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EMT50788.1 - 6.5e-06 26.3 0.1 1.8e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EMT50788.1 - 0.031 14.5 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EMT50788.1 - 0.036 13.7 0.3 0.081 12.6 0.3 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EMT50788.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Prenylcys_lyase PF07156.14 EMT50788.1 - 0.086 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase tRNA-synt_1_2 PF13603.6 EMT50789.1 - 4e-71 238.4 0.0 6.4e-71 237.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 EMT50789.1 - 1.3e-69 235.0 5.7 1e-45 156.2 5.6 4.6 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EMT50789.1 - 3.8e-27 95.1 2.8 6.7e-18 64.6 0.0 4.7 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EMT50789.1 - 1.1e-22 80.7 1.0 5.8e-22 78.3 1.0 2.1 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EMT50789.1 - 9.9e-05 21.8 0.0 0.038 13.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EMT50789.1 - 0.0052 15.7 0.0 0.029 13.3 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (K) DUF3094 PF11293.8 EMT50789.1 - 0.092 12.5 0.3 3.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) DUF2744 PF10910.8 EMT50789.1 - 0.11 12.5 0.1 33 4.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2744) tRNA-synt_1d PF00750.19 EMT50789.1 - 0.13 11.2 0.1 1.4 7.8 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class I (R) Methyltransf_25 PF13649.6 EMT50790.1 - 2.7e-20 72.9 0.0 4.8e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT50790.1 - 9.8e-16 58.2 0.0 1.6e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT50790.1 - 1.6e-12 47.6 0.0 2.6e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT50790.1 - 2.6e-12 47.3 0.0 4.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT50790.1 - 4.5e-11 42.8 0.0 5.4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT50790.1 - 7.2e-09 35.3 0.0 9.5e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EMT50790.1 - 4.3e-08 32.9 0.0 6.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EMT50790.1 - 2e-07 30.8 0.0 2.8e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 EMT50790.1 - 2.7e-06 26.6 0.0 3.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.14 EMT50790.1 - 1.1e-05 25.0 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 EMT50790.1 - 8e-05 22.1 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 EMT50790.1 - 0.00059 19.9 0.0 0.00083 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMT50790.1 - 0.0017 17.8 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EMT50790.1 - 0.0043 16.7 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TPMT PF05724.11 EMT50790.1 - 0.0093 15.6 0.0 0.018 14.7 0.0 1.5 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_2 PF00891.18 EMT50790.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain N2227 PF07942.12 EMT50790.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein FtsJ PF01728.19 EMT50790.1 - 0.011 15.8 0.1 0.11 12.6 0.1 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase AdoMet_MTase PF07757.13 EMT50790.1 - 0.03 14.7 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_24 PF13578.6 EMT50790.1 - 0.035 15.1 0.0 0.072 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 EMT50790.1 - 0.065 13.1 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SAM_MT PF04445.13 EMT50790.1 - 0.082 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase MethyltransfD12 PF02086.15 EMT50790.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_4 PF02390.17 EMT50790.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF4904 PF16247.5 EMT50790.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) tRNA_U5-meth_tr PF05958.11 EMT50790.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase RsfS PF02410.15 EMT50791.1 - 9.2e-27 93.4 0.6 1.1e-26 93.2 0.6 1.0 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation DUF5461 PF17545.2 EMT50791.1 - 0.092 13.1 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5461) AsnC_trans_reg2 PF17805.1 EMT50791.1 - 0.17 12.0 0.8 0.56 10.4 0.0 2.1 3 0 0 3 3 3 0 AsnC-like ligand binding domain HD PF01966.22 EMT50792.1 - 6.4e-17 61.9 0.0 9.8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 EMT50792.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 HDOD domain CTP_transf_like PF01467.26 EMT50793.1 - 1.7e-31 109.3 0.0 2e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like CRS1_YhbY PF01985.21 EMT50794.1 - 2e-23 82.4 0.3 2.3e-23 82.1 0.3 1.0 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain NBD_C PF17042.5 EMT50794.1 - 0.029 14.9 0.1 0.037 14.6 0.1 1.1 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain Shikimate_dh_N PF08501.11 EMT50795.1 - 5.2e-33 113.1 0.0 8.9e-33 112.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EMT50795.1 - 1.4e-14 53.6 0.5 2.7e-14 52.6 0.5 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EMT50795.1 - 4.4e-10 39.8 0.1 7.8e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EMT50795.1 - 0.00012 22.5 0.2 0.00032 21.2 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EMT50795.1 - 0.00023 21.4 0.1 0.00064 20.0 0.1 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 EMT50795.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 EMT50795.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MMR_HSR1 PF01926.23 EMT50796.1 - 2.4e-13 50.2 0.0 5.6e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMT50796.1 - 4.3e-08 33.2 0.0 7.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase Roc PF08477.13 EMT50796.1 - 5.7e-06 26.5 0.0 0.1 12.8 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EMT50796.1 - 8.1e-05 22.2 0.0 0.00022 20.8 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EMT50796.1 - 0.00047 19.7 0.0 0.23 11.0 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.22 EMT50796.1 - 0.00062 19.4 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 2 Ras family Dynamin_N PF00350.23 EMT50796.1 - 0.0032 17.6 0.2 0.38 10.8 0.0 2.3 1 1 0 2 2 2 1 Dynamin family Arf PF00025.21 EMT50796.1 - 0.023 14.1 0.1 4.3 6.8 0.0 2.4 1 1 1 2 2 2 0 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 EMT50796.1 - 0.027 14.5 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 EMT50796.1 - 0.031 14.8 0.1 0.048 14.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EMT50796.1 - 0.092 13.1 0.1 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain HAD_2 PF13419.6 EMT50797.1 - 8.7e-13 48.7 0.0 3.3e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMT50797.1 - 4.6e-12 46.7 0.2 1.3e-11 45.2 0.2 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EMT50797.1 - 1.7e-10 40.8 0.7 2.3e-09 37.1 0.7 2.0 1 1 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EMT50797.1 - 4.5e-10 39.5 0.0 7.9e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EMT50797.1 - 2.7e-06 27.4 0.0 9.3e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMT50797.1 - 4.1e-06 26.7 0.0 6e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMT50797.1 - 0.0021 18.5 0.1 0.0099 16.3 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Diphthami_syn_2 PF01902.17 EMT50797.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Diphthamide synthase 5_nucleotid PF05761.14 EMT50797.1 - 0.013 14.5 0.0 0.45 9.4 0.0 2.3 1 1 1 2 2 2 0 5' nucleotidase family DUF2608 PF11019.8 EMT50797.1 - 0.025 14.1 0.1 0.031 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Glyco_trans_4_2 PF13477.6 EMT50797.1 - 0.034 14.2 0.0 0.075 13.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase 4-like rve_3 PF13683.6 EMT50797.1 - 0.12 12.2 0.0 13 5.6 0.0 2.6 3 0 0 3 3 3 0 Integrase core domain IMS PF00817.20 EMT50800.1 - 1.5e-46 158.1 0.0 2.9e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EMT50800.1 - 7.9e-15 55.6 0.0 1.8e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EMT50800.1 - 0.00029 21.0 0.0 0.0008 19.6 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Pro-NT_NN PF07421.11 EMT50800.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor AhpC-TSA PF00578.21 EMT50801.1 - 1.2e-28 99.5 0.0 1.4e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMT50801.1 - 2e-19 69.7 0.0 2.4e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin DUF4174 PF13778.6 EMT50801.1 - 0.042 14.3 0.0 0.059 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) DUF899 PF05988.12 EMT50801.1 - 0.047 13.2 0.0 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Peptidase_C26 PF07722.13 EMT50802.1 - 1.4e-58 198.2 0.0 1.6e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 EMT50802.1 - 5e-16 59.0 0.0 7.6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_5 PF13507.6 EMT50802.1 - 0.021 13.9 0.0 3.7 6.6 0.0 2.1 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 EMT50802.1 - 0.17 11.5 0.2 0.33 10.5 0.1 1.5 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain SBP_bac_5 PF00496.22 EMT50803.1 - 1.2e-89 301.0 10.8 1.7e-89 300.5 10.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Beta-lactamase2 PF13354.6 EMT50804.1 - 8.2e-59 198.6 0.0 9.8e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 EMT50804.1 - 0.0005 19.6 0.1 0.00072 19.1 0.1 1.3 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Transpeptidase PF00905.22 EMT50804.1 - 0.0011 18.3 0.1 0.0087 15.3 0.0 1.9 1 1 1 2 2 2 1 Penicillin binding protein transpeptidase domain ECF-ribofla_trS PF07155.12 EMT50805.1 - 4.4e-20 72.4 14.3 5.4e-20 72.1 14.3 1.0 1 0 0 1 1 1 1 ECF-type riboflavin transporter, S component ECF_trnsprt PF12822.7 EMT50805.1 - 4.4e-07 30.2 13.6 5.6e-07 29.8 13.6 1.1 1 0 0 1 1 1 1 ECF transporter, substrate-specific component ABC2_membrane_5 PF13346.6 EMT50805.1 - 0.57 9.7 10.4 0.11 12.1 0.3 2.5 1 1 2 3 3 3 0 ABC-2 family transporter protein Phage_holin_5_1 PF06946.11 EMT50805.1 - 10 6.6 8.7 0.87 10.0 2.5 2.2 1 1 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 Amino_oxidase PF01593.24 EMT50806.1 - 4.7e-21 75.6 0.0 1.6e-20 73.9 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMT50806.1 - 1.5e-12 47.6 0.5 4.5e-12 46.0 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMT50806.1 - 1e-11 45.1 1.1 2.2e-07 30.8 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMT50806.1 - 5e-08 32.4 3.7 1.3e-06 27.7 4.0 2.1 2 0 0 2 2 2 1 FAD binding domain GDI PF00996.18 EMT50806.1 - 4.2e-07 28.9 1.1 0.0056 15.3 0.3 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor FAD_oxidored PF12831.7 EMT50806.1 - 5.9e-07 29.2 0.3 2.2e-06 27.3 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMT50806.1 - 9.1e-07 28.4 0.7 2.3e-06 27.0 0.1 2.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMT50806.1 - 1.7e-06 28.5 3.9 0.00036 21.0 0.9 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMT50806.1 - 3.9e-06 26.4 1.2 3.9e-06 26.4 1.2 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EMT50806.1 - 4.8e-06 25.5 1.4 4.8e-05 22.2 0.7 2.3 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EMT50806.1 - 7.5e-06 25.3 1.3 1.4e-05 24.5 0.3 1.8 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EMT50806.1 - 7.5e-05 22.0 0.8 0.00016 20.9 0.8 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EMT50806.1 - 0.00013 21.2 4.4 0.0012 17.9 1.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EMT50806.1 - 0.0027 16.6 0.5 0.015 14.1 0.4 1.9 2 0 0 2 2 2 1 Tryptophan halogenase AlaDh_PNT_C PF01262.21 EMT50806.1 - 0.01 15.2 0.8 0.023 14.0 0.8 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 EMT50806.1 - 0.015 14.1 0.3 0.029 13.2 0.3 1.4 1 0 0 1 1 1 0 MCRA family Pyr_redox_3 PF13738.6 EMT50806.1 - 0.018 14.3 1.3 0.018 14.3 1.3 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ubiquitin_5 PF18037.1 EMT50806.1 - 0.085 13.2 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain GMC_oxred_N PF00732.19 EMT50806.1 - 0.16 11.3 0.1 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Virulence_fact PF13769.6 EMT50807.1 - 1.6e-31 108.3 0.7 4.1e-31 107.1 0.1 2.0 2 0 0 2 2 2 1 Virulence factor HEAT_2 PF13646.6 EMT50807.1 - 1.6e-24 86.1 3.3 7.7e-15 55.1 0.8 2.4 1 1 1 2 2 2 2 HEAT repeats Nfu_N PF08712.11 EMT50807.1 - 2.2e-16 59.7 0.0 4.6e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal HEAT PF02985.22 EMT50807.1 - 5.5e-13 48.0 1.0 0.011 15.9 0.0 5.1 5 0 0 5 5 5 4 HEAT repeat HEAT_PBS PF03130.16 EMT50807.1 - 5.2e-10 39.0 4.2 0.0035 17.9 0.6 4.4 4 0 0 4 4 4 3 PBS lyase HEAT-like repeat Cnd1 PF12717.7 EMT50807.1 - 0.0001 22.4 0.0 0.0033 17.5 0.0 2.9 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EMT50807.1 - 0.0016 18.9 1.5 3.1 8.4 0.0 4.0 4 0 0 4 4 4 2 HEAT-like repeat Acetyltransf_1 PF00583.25 EMT50808.1 - 2.2e-23 82.7 0.0 2.3e-16 60.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT50808.1 - 3.7e-18 65.7 0.0 1.3e-11 44.7 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT50808.1 - 6.1e-17 61.7 0.0 4.1e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMT50808.1 - 4.8e-16 59.7 0.5 2.5e-11 44.4 0.0 3.0 1 1 2 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT50808.1 - 2.8e-09 36.8 0.0 1e-07 31.8 0.0 2.8 3 0 0 3 3 3 1 FR47-like protein Acetyltransf_9 PF13527.7 EMT50808.1 - 2.6e-07 30.8 0.0 0.028 14.5 0.0 3.6 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT50808.1 - 5.6e-06 26.6 0.0 0.00062 19.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMT50808.1 - 0.0058 16.3 0.0 0.033 13.9 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF727 PF05303.12 EMT50808.1 - 0.006 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Acetyltransf_15 PF17013.5 EMT50808.1 - 0.011 15.2 0.0 0.29 10.6 0.0 2.4 2 1 0 2 2 2 0 Putative acetyl-transferase GNAT_acetyltr_2 PF13718.6 EMT50808.1 - 0.11 11.9 0.1 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 GNAT acetyltransferase 2 DUF4931 PF16285.5 EMT50809.1 - 3.3e-112 373.7 0.0 3.7e-112 373.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) GalP_UDP_transf PF01087.22 EMT50809.1 - 0.015 15.7 0.0 0.038 14.4 0.0 1.6 1 1 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain zf-ribbon_3 PF13248.6 EMT50811.1 - 3.1e-07 29.6 1.7 4.8e-07 29.0 1.7 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 EMT50811.1 - 1e-06 28.2 4.7 1.7e-06 27.5 4.7 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EMT50811.1 - 2.9e-06 27.2 1.1 4.4e-06 26.6 1.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 EMT50811.1 - 1.4e-05 25.8 0.4 1.8e-05 25.4 0.4 1.3 1 0 0 1 1 1 1 zinc-ribbon family zf-NADH-PPase PF09297.11 EMT50811.1 - 6.6e-05 22.5 5.7 0.064 12.9 0.2 2.3 1 1 1 2 2 2 2 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 EMT50811.1 - 0.0026 17.6 7.9 0.093 12.7 0.2 2.7 3 0 0 3 3 3 2 Nudix N-terminal zf_UBZ PF18439.1 EMT50811.1 - 0.011 15.3 2.9 0.11 12.1 0.3 2.2 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 EMT50811.1 - 0.024 14.7 3.7 0.043 13.9 3.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.12 EMT50811.1 - 0.05 13.6 0.3 0.083 12.9 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbons DUF4199 PF13858.6 EMT50811.1 - 0.053 13.9 3.5 0.067 13.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) GFA PF04828.14 EMT50811.1 - 0.069 13.5 2.4 1.4 9.3 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.10 EMT50811.1 - 0.07 12.9 2.4 0.38 10.5 2.4 2.1 1 1 0 1 1 1 0 A2L zinc ribbon domain zf_C2H2_13 PF18508.1 EMT50811.1 - 0.071 12.7 6.0 0.31 10.7 0.8 2.3 1 1 1 2 2 2 0 Zinc finger domain NOB1_Zn_bind PF08772.11 EMT50811.1 - 0.078 13.1 5.6 3.1 8.0 0.2 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF2116 PF09889.9 EMT50811.1 - 0.1 12.6 0.7 0.1 12.6 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) OrfB_Zn_ribbon PF07282.11 EMT50811.1 - 0.11 12.5 2.2 0.18 11.7 2.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain HypA PF01155.19 EMT50811.1 - 0.11 12.5 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RNA_POL_M_15KD PF02150.16 EMT50811.1 - 0.13 12.2 4.7 1.2 9.0 0.3 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit YtpI PF14007.6 EMT50811.1 - 0.17 12.0 2.4 0.37 11.0 2.4 1.5 1 0 0 1 1 1 0 YtpI-like protein DNA_ligase_ZBD PF03119.16 EMT50811.1 - 0.23 11.5 3.7 1.8 8.7 0.2 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.10 EMT50811.1 - 0.25 11.5 3.9 4.4 7.5 0.1 2.4 1 1 1 2 2 2 0 Zinc ribbon domain DHHC PF01529.20 EMT50811.1 - 0.78 9.9 5.6 7.3 6.7 0.4 2.6 2 1 0 2 2 2 0 DHHC palmitoyltransferase Ogr_Delta PF04606.12 EMT50811.1 - 0.83 9.7 3.4 14 5.8 0.1 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Cys_rich_CPXG PF14255.6 EMT50811.1 - 1.5 8.8 5.7 0.71 9.8 0.8 2.1 2 0 0 2 2 2 0 Cysteine-rich CPXCG DUF1610 PF07754.11 EMT50811.1 - 2 8.4 7.0 7 6.7 1.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Zn_Tnp_IS1595 PF12760.7 EMT50811.1 - 3.4 7.7 7.2 11 6.1 0.7 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-C2HC_2 PF13913.6 EMT50811.1 - 7.9 6.5 7.3 12 5.9 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Gmad2 PF10648.9 EMT50813.1 - 1.1e-20 73.6 0.5 1.8e-20 72.9 0.5 1.3 1 0 0 1 1 1 1 Immunoglobulin-like domain of bacterial spore germination DUF1180 PF06679.12 EMT50813.1 - 0.084 13.3 0.1 0.098 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) LPAM_1 PF08139.12 EMT50813.1 - 0.19 12.3 2.3 0.37 11.4 2.3 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Hamartin PF04388.12 EMT50813.1 - 0.26 9.9 1.5 0.28 9.8 1.5 1.0 1 0 0 1 1 1 0 Hamartin protein MSA-2c PF12238.8 EMT50813.1 - 1.6 8.7 8.9 2.6 8.0 8.9 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c MFS_1 PF07690.16 EMT50815.1 - 4e-27 95.1 91.2 2.7e-22 79.2 52.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT50815.1 - 0.0036 16.2 3.1 0.0036 16.2 3.1 2.5 1 1 2 3 3 3 2 MFS_1 like family FCD PF07729.12 EMT50816.1 - 6.1e-20 71.9 9.2 1e-19 71.2 9.2 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EMT50816.1 - 1.2e-18 66.5 0.3 4.2e-18 64.8 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family FadR_C PF07840.12 EMT50816.1 - 6.8e-05 22.8 0.1 9.9e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 FadR C-terminal domain HTH_IclR PF09339.10 EMT50816.1 - 7.3e-05 22.5 1.3 0.0015 18.2 0.1 3.0 3 0 0 3 3 3 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EMT50816.1 - 0.003 17.4 0.2 0.073 13.0 0.0 2.6 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 EMT50816.1 - 0.0037 17.1 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_41 PF14502.6 EMT50816.1 - 0.02 14.5 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 EMT50816.1 - 0.023 14.9 0.4 0.44 10.8 0.0 3.2 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_DeoR PF08220.12 EMT50816.1 - 0.034 13.9 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EMT50816.1 - 0.053 13.5 0.0 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 HTH domain Penicillinase_R PF03965.16 EMT50816.1 - 0.063 13.6 0.6 1.4 9.3 0.1 2.3 2 0 0 2 2 2 0 Penicillinase repressor HTH_36 PF13730.6 EMT50816.1 - 0.084 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain PaaX PF07848.12 EMT50816.1 - 0.11 12.8 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 PaaX-like protein SIR2 PF02146.17 EMT50818.1 - 3.7e-47 160.5 0.0 4.4e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EMT50818.1 - 0.0025 17.5 0.0 0.039 13.7 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Metallophos PF00149.28 EMT50819.1 - 6.8e-18 65.9 0.0 1.2e-17 65.2 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 EMT50819.1 - 1.8e-06 26.6 0.1 0.0054 15.1 0.0 3.0 3 0 0 3 3 3 3 Firmicute fructose-1,6-bisphosphatase Metallophos_2 PF12850.7 EMT50819.1 - 1.9e-06 28.2 0.0 1.1e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CopC PF04234.12 EMT50820.1 - 3.7e-19 69.6 0.2 3.7e-19 69.6 0.2 2.1 2 1 0 2 2 2 1 CopC domain CopD PF05425.13 EMT50820.1 - 8.7e-17 61.4 10.6 8.7e-17 61.4 10.6 3.4 2 1 0 3 3 3 1 Copper resistance protein D Big_5 PF13205.6 EMT50820.1 - 0.0018 18.9 0.1 0.0052 17.5 0.1 1.7 1 0 0 1 1 1 1 Bacterial Ig-like domain UvrB_inter PF17757.1 EMT50820.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 UvrB interaction domain Macoilin PF09726.9 EMT50820.1 - 0.98 7.9 5.2 1.3 7.5 5.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF4198 PF10670.9 EMT50821.1 - 1.1e-24 88.0 0.1 2.7e-24 86.8 0.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4198) bMG3 PF11974.8 EMT50821.1 - 8.8e-06 25.7 0.0 5.9e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 Bacterial alpha-2-macroglobulin MG3 domain OprD PF03573.13 EMT50821.1 - 0.015 14.4 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 outer membrane porin, OprD family SpaA PF17802.1 EMT50821.1 - 0.058 13.7 0.1 0.058 13.7 0.1 2.9 2 1 1 3 3 3 0 Prealbumin-like fold domain Y_Y_Y PF07495.13 EMT50821.1 - 0.065 13.2 0.3 0.85 9.6 0.1 2.6 1 1 1 2 2 2 0 Y_Y_Y domain CarboxypepD_reg PF13620.6 EMT50821.1 - 0.069 13.4 7.1 0.2 12.0 0.3 3.9 3 1 1 4 4 4 0 Carboxypeptidase regulatory-like domain Cu_amine_oxidN1 PF07833.11 EMT50821.1 - 0.098 13.2 0.2 1.8 9.1 0.0 2.8 2 1 0 2 2 2 0 Copper amine oxidase N-terminal domain DsbB PF02600.16 EMT50822.1 - 8.7e-14 52.2 10.2 8.7e-13 48.9 10.2 1.9 1 1 0 1 1 1 1 Disulfide bond formation protein DsbB Asp_Glu_race PF01177.22 EMT50822.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase DUF2070 PF09843.9 EMT50822.1 - 0.81 7.9 3.1 0.94 7.7 3.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Thioredoxin PF00085.20 EMT50823.1 - 7.8e-14 51.5 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMT50823.1 - 2.5e-06 27.9 0.2 0.00044 20.7 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EMT50823.1 - 0.00016 21.7 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_6 PF13848.6 EMT50823.1 - 0.0056 16.6 0.1 0.0077 16.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 EMT50823.1 - 0.0087 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 EMT50823.1 - 0.033 14.0 0.0 0.073 12.9 0.0 1.6 1 1 0 1 1 1 0 F plasmid transfer operon protein PIRT PF15099.6 EMT50823.1 - 0.034 13.7 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family TilS_C PF11734.8 EMT50823.1 - 0.13 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 TilS substrate C-terminal domain YtkA PF13115.6 EMT50824.1 - 7.6e-27 93.8 13.0 4e-14 53.0 0.7 2.8 3 0 0 3 3 3 2 YtkA-like Invasin_D3 PF09134.10 EMT50824.1 - 5.6e-08 33.0 1.2 0.0081 16.5 0.1 2.4 2 1 0 2 2 2 2 Invasin, domain 3 DUF3823 PF12866.7 EMT50824.1 - 9.9e-07 29.0 0.9 0.0005 20.3 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3823) N-terminal domain CopC PF04234.12 EMT50824.1 - 0.00011 23.2 7.4 0.00083 20.3 0.2 2.7 2 1 0 2 2 2 1 CopC domain PKD PF00801.20 EMT50824.1 - 0.0025 17.6 1.9 1.1 9.1 0.3 2.9 2 1 0 2 2 2 2 PKD domain DUF5006 PF16397.5 EMT50824.1 - 0.0043 16.3 0.1 0.0095 15.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5006) MG2 PF01835.19 EMT50824.1 - 0.008 16.6 3.6 1.5 9.3 0.3 2.4 2 0 0 2 2 2 2 MG2 domain DUF3324 PF11797.8 EMT50824.1 - 0.023 14.7 6.2 2.4 8.2 1.4 3.1 2 2 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) FixG_C PF11614.8 EMT50824.1 - 1.2 9.4 3.4 31 4.8 0.1 3.0 3 1 1 4 4 4 0 IG-like fold at C-terminal of FixG, putative oxidoreductase EMP24_GP25L PF01105.24 EMT50824.1 - 1.2 9.0 9.1 0.8 9.6 4.4 2.5 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Cu_amine_oxidN1 PF07833.11 EMT50825.1 - 9.1e-31 106.2 0.0 1.5e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase N-terminal domain Glyco_hydro_18 PF00704.28 EMT50825.1 - 5.4e-13 49.4 0.0 2.8e-09 37.1 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 DUF1749 PF08538.10 EMT50825.1 - 0.065 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) GreA_GreB PF01272.19 EMT50826.1 - 2e-15 56.4 0.0 3.3e-15 55.7 0.0 1.3 1 1 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term DNA_pol_lambd_f PF10391.9 EMT50826.1 - 0.11 12.3 0.1 0.32 10.9 0.1 1.7 1 1 1 2 2 2 0 Fingers domain of DNA polymerase lambda NLPC_P60 PF00877.19 EMT50828.1 - 1.5e-30 105.3 5.9 2.9e-14 53.0 0.1 2.7 2 1 0 2 2 2 2 NlpC/P60 family Peptidase_C92 PF05708.12 EMT50828.1 - 6e-08 33.0 0.0 0.00018 21.7 0.0 3.2 3 1 0 3 3 3 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF1175 PF06672.11 EMT50828.1 - 5.6e-05 22.9 0.1 0.028 14.1 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1175) CHAP PF05257.16 EMT50828.1 - 0.0018 18.8 0.2 0.5 11.0 0.1 2.4 2 0 0 2 2 2 2 CHAP domain EVE PF01878.18 EMT50828.1 - 0.052 13.6 0.2 5.4 7.0 0.0 2.3 2 0 0 2 2 2 0 EVE domain Mur_ligase_M PF08245.12 EMT50829.1 - 1.1e-35 123.4 0.0 1.6e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EMT50829.1 - 1e-09 38.5 0.0 2.5e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain SBD_N PF07005.11 EMT50829.1 - 0.13 12.0 0.0 0.88 9.2 0.0 2.0 2 0 0 2 2 2 0 Sugar-binding N-terminal domain Phosphodiest PF01663.22 EMT50830.1 - 2.4e-20 73.4 0.0 6.3e-20 72.1 0.0 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Na_H_Exchanger PF00999.21 EMT50831.1 - 4.3e-57 193.6 51.9 5.2e-57 193.4 51.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_C PF02080.21 EMT50831.1 - 3.4e-11 42.8 0.0 6.2e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-C domain TRAM1 PF08390.11 EMT50831.1 - 0.044 13.4 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 TRAM1-like protein DUF3176 PF11374.8 EMT50831.1 - 0.066 13.4 0.5 0.066 13.4 0.5 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3176) TetR_N PF00440.23 EMT50832.1 - 6.6e-12 45.0 0.0 1.6e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 EMT50832.1 - 0.019 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal DUF2306 PF10067.9 EMT50833.1 - 9e-08 32.4 4.0 9e-08 32.4 4.0 2.0 2 1 0 2 2 2 1 Predicted membrane protein (DUF2306) PelG PF16933.5 EMT50833.1 - 1.2e-05 24.3 6.5 1.2e-05 24.3 6.5 1.5 2 0 0 2 2 2 1 Putative exopolysaccharide Exporter (EPS-E) DUF1129 PF06570.11 EMT50833.1 - 1.6 8.1 10.9 0.16 11.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) MazG PF03819.17 EMT50834.1 - 7.9e-10 38.8 0.5 1.1e-09 38.4 0.5 1.1 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 EMT50834.1 - 0.00058 20.1 0.1 0.00078 19.7 0.1 1.4 1 1 0 1 1 1 1 MazG-like family PRA-PH PF01503.17 EMT50834.1 - 0.0014 19.0 0.0 0.0018 18.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Lysine_decarbox PF03641.14 EMT50835.1 - 3.2e-38 130.8 0.0 3.8e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EMT50835.1 - 1.3e-15 57.3 0.0 1.7e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 SLOG cluster4 family DAGK_cat PF00781.24 EMT50835.1 - 0.02 14.5 0.1 3.4 7.3 0.0 2.1 1 1 1 2 2 2 0 Diacylglycerol kinase catalytic domain TrkA_C PF02080.21 EMT50836.1 - 4.9e-15 55.1 0.0 9.7e-15 54.2 0.0 1.5 2 0 0 2 2 2 1 TrkA-C domain Na_H_Exchanger PF00999.21 EMT50837.1 - 1.6e-60 205.0 50.6 2e-60 204.6 50.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_C PF02080.21 EMT50838.1 - 2.3e-14 53.0 0.0 6.4e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 TrkA-C domain Spore_YhcN_YlaJ PF09580.10 EMT50840.1 - 5.8e-07 29.7 0.0 7.4e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Conotoxin PF02950.17 EMT50840.1 - 0.08 14.0 1.3 0.42 11.7 0.0 2.2 2 0 0 2 2 2 0 Conotoxin IlvGEDA_leader PF08046.11 EMT50840.1 - 0.086 12.3 0.5 0.14 11.6 0.5 1.3 1 0 0 1 1 1 0 IlvGEDA operon leader peptide DUF5446 PF17522.2 EMT50840.1 - 0.31 11.2 3.9 2 8.6 0.3 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5446) Sigma70_r4 PF04545.16 EMT50841.1 - 2.6e-16 58.9 0.8 4.2e-16 58.2 0.8 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 EMT50841.1 - 8.3e-07 28.6 0.1 1.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_3 PF01381.22 EMT50841.1 - 2.5e-06 27.5 0.4 6e-06 26.2 0.2 1.7 2 0 0 2 2 2 1 Helix-turn-helix MarR_2 PF12802.7 EMT50841.1 - 1.6e-05 24.7 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_19 PF12844.7 EMT50841.1 - 0.00014 21.8 0.1 0.00034 20.6 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 EMT50841.1 - 0.0002 20.9 0.0 0.00035 20.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 EMT50841.1 - 0.00021 21.6 0.2 0.0007 19.9 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.6 EMT50841.1 - 0.00028 21.0 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 EMT50841.1 - 0.00035 20.3 0.2 0.0007 19.3 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain KORA PF16509.5 EMT50841.1 - 0.00075 19.7 0.1 0.0012 19.1 0.1 1.6 1 1 0 1 1 1 1 TrfB plasmid transcriptional repressor Trp_repressor PF01371.19 EMT50841.1 - 0.0017 18.4 0.4 0.0024 17.9 0.4 1.3 1 0 0 1 1 1 1 Trp repressor protein Sigma70_r4_2 PF08281.12 EMT50841.1 - 0.0023 17.6 1.7 0.017 14.8 1.2 2.4 1 1 1 2 2 2 1 Sigma-70, region 4 HTH_10 PF04967.12 EMT50841.1 - 0.0034 17.2 0.1 0.0067 16.2 0.1 1.5 1 0 0 1 1 1 1 HTH DNA binding domain HTH_29 PF13551.6 EMT50841.1 - 0.0036 17.3 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix GerE PF00196.19 EMT50841.1 - 0.01 15.4 0.1 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_Crp_2 PF13545.6 EMT50841.1 - 0.011 15.7 0.1 0.025 14.6 0.1 1.7 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain HTH_25 PF13413.6 EMT50841.1 - 0.016 15.0 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 EMT50841.1 - 0.026 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 EMT50841.1 - 0.043 13.7 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 MarR family KorB PF08535.10 EMT50841.1 - 0.052 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 KorB domain CENP-B_N PF04218.13 EMT50841.1 - 0.056 13.1 0.3 0.12 12.0 0.3 1.7 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 EMT50841.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_AsnC-type PF13404.6 EMT50841.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 EMT50841.1 - 0.076 12.9 3.0 0.08 12.8 0.0 2.3 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family HTH_AraC PF00165.23 EMT50841.1 - 0.081 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family TrmB PF01978.19 EMT50841.1 - 0.11 12.4 0.1 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_6 PF01418.17 EMT50841.1 - 0.12 12.4 0.2 0.39 10.7 0.1 1.9 2 1 0 2 2 2 0 Helix-turn-helix domain, rpiR family Resolvase PF00239.21 EMT50842.1 - 2.6e-33 115.2 0.3 2.6e-33 115.2 0.3 2.4 2 0 0 2 2 2 1 Resolvase, N terminal domain Recombinase PF07508.13 EMT50842.1 - 4.8e-19 68.7 0.1 1.3e-18 67.3 0.1 1.8 1 0 0 1 1 1 1 Recombinase Zn_ribbon_recom PF13408.6 EMT50842.1 - 1.4e-11 44.7 1.0 2.8e-11 43.8 1.0 1.5 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain 4HB_MCP_1 PF12729.7 EMT50842.1 - 0.015 14.8 1.9 0.028 14.0 1.9 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction CPSase_L_D3 PF02787.19 EMT50842.1 - 0.085 13.2 1.0 2.9 8.3 0.0 2.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Seryl_tRNA_N PF02403.22 EMT50842.1 - 0.16 12.2 8.2 0.12 12.6 5.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 EMT50842.1 - 1.3 7.6 5.5 1.9 7.0 5.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A GTP-bdg_M PF16360.5 EMT50842.1 - 2.4 8.8 13.2 0.27 11.9 8.0 2.1 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region DivIC PF04977.15 EMT50842.1 - 4.1 7.2 12.4 7.1 6.5 7.5 2.6 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 EMT50842.1 - 6.3 7.3 19.8 3 8.4 15.4 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region ParBc PF02195.18 EMT50843.1 - 0.00015 22.0 0.0 0.00021 21.5 0.0 1.2 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_Crp_2 PF13545.6 EMT50844.1 - 0.02 14.8 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Ribos_L4_asso_C PF14374.6 EMT50844.1 - 0.1 12.7 0.1 0.67 10.1 0.1 2.1 1 1 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain Peptidase_C39_2 PF13529.6 EMT50846.1 - 5.7e-13 49.6 0.1 9.1e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 EMT50846.1 - 7.6e-13 48.7 0.0 1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C10 PF01640.17 EMT50846.1 - 0.0019 18.6 0.4 0.0026 18.1 0.4 1.3 1 1 0 1 1 1 1 Peptidase C10 family ABA_WDS PF02496.16 EMT50849.1 - 0.033 14.7 0.0 0.034 14.6 0.0 1.1 1 0 0 1 1 1 0 ABA/WDS induced protein Amino_oxidase PF01593.24 EMT50850.1 - 1.6e-70 238.7 0.0 3.9e-70 237.4 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMT50850.1 - 6.5e-11 42.3 0.2 1.3e-10 41.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMT50850.1 - 4.6e-05 22.7 0.1 7.6e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EMT50850.1 - 6.5e-05 22.3 0.0 9.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMT50850.1 - 0.00018 20.9 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT50850.1 - 0.0052 15.5 0.5 0.0079 14.9 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EMT50850.1 - 0.0059 17.1 0.6 0.012 16.2 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMT50850.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EMT50850.1 - 0.021 14.2 0.1 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EMT50850.1 - 0.022 14.0 0.2 0.05 12.8 0.0 1.6 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 EMT50850.1 - 0.081 12.6 0.9 0.16 11.6 0.9 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MtrD PF04207.12 EMT50850.1 - 0.12 12.0 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D Pyr_redox_3 PF13738.6 EMT50850.1 - 0.15 11.3 0.8 0.23 10.7 0.4 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMT50850.1 - 0.5 9.9 2.1 1 8.8 2.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ribosomal_S14 PF00253.21 EMT50851.1 - 2e-25 88.3 4.3 2.2e-25 88.1 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4025 PF13217.6 EMT50852.1 - 1.5e-21 75.9 0.8 2.2e-21 75.4 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4025) Peptidase_M42 PF05343.14 EMT50853.1 - 3.1e-108 361.2 0.0 3.8e-108 361.0 0.0 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 EMT50853.1 - 9.4e-09 35.3 0.0 2.2e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M18 PF02127.15 EMT50853.1 - 0.06 12.1 0.0 7.8 5.2 0.0 2.1 2 0 0 2 2 2 0 Aminopeptidase I zinc metalloprotease (M18) DHOR PF06537.11 EMT50854.1 - 0.0054 15.4 0.1 0.014 14.0 0.0 1.6 2 0 0 2 2 2 1 Di-haem oxidoreductase, putative peroxidase Cytochrome_C7 PF14522.6 EMT50854.1 - 0.0081 16.1 0.3 2.9 7.9 0.1 2.3 2 0 0 2 2 2 2 Cytochrome c7 and related cytochrome c Cytochrom_C PF00034.21 EMT50854.1 - 0.011 16.9 2.3 31 5.8 0.0 3.9 3 1 1 4 4 4 0 Cytochrome c Cytochrome_CBB3 PF13442.6 EMT50854.1 - 0.014 15.7 0.1 2.6 8.5 0.0 3.2 3 0 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III Paired_CXXCH_1 PF09699.10 EMT50854.1 - 0.066 13.0 0.3 9.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C554 PF13435.6 EMT50854.1 - 0.11 13.4 0.9 40 5.2 0.0 2.9 3 0 0 3 3 3 0 Cytochrome c554 and c-prime DUF3365 PF11845.8 EMT50854.1 - 0.11 12.8 0.0 2.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) BcrAD_BadFG PF01869.20 EMT50856.1 - 1.4e-67 228.0 3.0 5.8e-44 150.6 0.1 2.5 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family DUF2229 PF09989.9 EMT50856.1 - 1.1e-54 185.3 0.0 2.1e-54 184.4 0.0 1.5 1 0 0 1 1 1 1 CoA enzyme activase uncharacterised domain (DUF2229) FGGY_N PF00370.21 EMT50856.1 - 1.7e-06 27.8 0.6 0.039 13.5 0.0 2.6 3 0 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain ROK PF00480.20 EMT50856.1 - 0.00027 20.5 2.6 0.011 15.3 0.1 3.0 3 0 0 3 3 3 1 ROK family DEDD_Tnp_IS110 PF01548.17 EMT50856.1 - 0.00034 20.5 0.7 0.82 9.5 0.1 2.9 2 0 0 2 2 2 2 Transposase Hydant_A_N PF05378.13 EMT50856.1 - 0.09 12.5 1.5 7.3 6.3 0.1 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region FtsA PF14450.6 EMT50856.1 - 0.17 12.3 0.6 18 5.8 0.0 3.7 4 1 0 4 4 4 0 Cell division protein FtsA MarR_2 PF12802.7 EMT50859.1 - 8.1e-14 51.3 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 EMT50859.1 - 1.7e-06 27.9 0.2 3.5e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 EMT50859.1 - 2.6e-06 27.2 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 EMT50859.1 - 1.7e-05 24.6 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 EMT50859.1 - 4.2e-05 23.5 0.0 6.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_24 PF13412.6 EMT50859.1 - 0.0012 18.4 0.0 0.0025 17.3 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 EMT50859.1 - 0.0012 19.0 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_28 PF13518.6 EMT50859.1 - 0.0043 17.1 0.0 0.0084 16.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_27 PF13463.6 EMT50859.1 - 0.0045 17.5 0.0 0.007 16.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain AphA_like PF14557.6 EMT50859.1 - 0.0068 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator HTH_20 PF12840.7 EMT50859.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain SMC_ScpB PF04079.16 EMT50859.1 - 0.036 13.7 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB DUF4364 PF14277.6 EMT50859.1 - 0.05 13.3 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) LZ_Tnp_IS481 PF13011.6 EMT50859.1 - 0.061 13.9 0.0 0.097 13.2 0.0 1.3 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DprA_WH PF17782.1 EMT50859.1 - 0.062 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 DprA winged helix domain HTH_IclR PF09339.10 EMT50859.1 - 0.067 13.0 0.1 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain GntR PF00392.21 EMT50859.1 - 0.091 12.4 0.2 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.15 EMT50859.1 - 0.12 12.4 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_34 PF13601.6 EMT50859.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF4037 PF13228.6 EMT50860.1 - 1.7e-06 28.8 0.0 3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4037) MFS_1 PF07690.16 EMT50861.1 - 3.5e-53 180.8 48.0 5e-39 134.2 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT50861.1 - 5.3e-19 68.3 28.8 1e-10 41.1 12.0 2.1 1 1 1 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 EMT50861.1 - 7.2e-12 44.5 16.6 7.2e-12 44.5 16.6 1.6 1 1 1 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.6 EMT50861.1 - 3.4e-11 42.4 32.3 5.4e-08 31.8 10.6 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 EMT50861.1 - 2.3e-09 37.0 27.4 3.2e-09 36.6 27.4 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 EMT50861.1 - 1.5e-06 27.4 39.0 0.00013 21.0 36.9 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EMT50861.1 - 0.003 15.9 17.3 0.082 11.2 2.5 3.4 2 2 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family UNC-93 PF05978.16 EMT50861.1 - 0.17 11.6 9.7 0.042 13.6 5.1 2.2 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Adenyl_transf PF04439.12 EMT50862.1 - 2.3e-129 430.5 1.8 2.6e-129 430.3 1.8 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Peptidase_M4_C PF02868.15 EMT50864.1 - 3.9e-61 205.8 0.3 8.9e-61 204.6 0.3 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 EMT50864.1 - 2.3e-50 170.9 6.5 5.7e-50 169.6 6.5 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain FTP PF07504.13 EMT50864.1 - 5.8e-14 51.7 0.2 2.1e-13 49.9 0.2 2.1 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 EMT50864.1 - 5.2e-12 46.1 0.5 1.2e-11 44.9 0.5 1.7 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain DUF4157 PF13699.6 EMT50864.1 - 0.13 12.5 0.1 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) KNTase_C PF07827.11 EMT50865.1 - 1.4e-56 189.9 0.0 1.9e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 KNTase C-terminal domain NTP_transf_2 PF01909.23 EMT50865.1 - 0.00071 19.8 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EMT50865.1 - 0.0017 18.4 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Glyco_hydro_18 PF00704.28 EMT50866.1 - 1.6e-28 100.4 0.3 2e-28 100.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EMT50866.1 - 1.1e-24 86.2 0.0 2e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 LysM domain Glyoxalase PF00903.25 EMT50867.1 - 1.2e-33 116.0 1.9 4e-33 114.3 1.9 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMT50867.1 - 0.016 15.5 0.1 3.7 7.9 0.0 2.7 2 1 1 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EMT50867.1 - 0.085 13.0 0.2 11 6.1 0.0 2.7 2 1 1 3 3 3 0 Glyoxalase-like domain DLH PF01738.18 EMT50868.1 - 1.2e-10 41.4 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EMT50868.1 - 1.4e-07 31.6 0.0 2e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EMT50868.1 - 3.1e-07 29.9 0.0 0.012 14.9 0.0 2.4 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMT50868.1 - 0.00059 19.4 0.0 0.32 10.4 0.0 2.4 2 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EMT50868.1 - 0.00063 19.7 0.0 0.015 15.2 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 EMT50868.1 - 0.029 14.0 0.0 0.17 11.5 0.0 2.2 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 EMT50868.1 - 0.035 14.2 0.0 0.071 13.2 0.0 1.5 2 0 0 2 2 2 0 TAP-like protein DSBA PF01323.20 EMT50868.1 - 0.057 13.2 0.0 4.4 7.0 0.0 2.1 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Rrf2 PF02082.20 EMT50869.1 - 1e-28 99.5 0.5 1.4e-28 99.1 0.1 1.4 2 0 0 2 2 1 1 Transcriptional regulator MarR_2 PF12802.7 EMT50869.1 - 6.1e-08 32.4 0.0 1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EMT50869.1 - 7.3e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 EMT50869.1 - 2.5e-05 24.1 0.0 4.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_5 PF01022.20 EMT50869.1 - 3.8e-05 23.5 0.1 0.00021 21.1 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 EMT50869.1 - 6.8e-05 23.0 0.2 0.00013 22.1 0.2 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HrcA_DNA-bdg PF03444.15 EMT50869.1 - 7.3e-05 22.3 0.4 0.0038 16.8 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_24 PF13412.6 EMT50869.1 - 0.0001 21.8 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EMT50869.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 EMT50869.1 - 0.00018 21.4 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_27 PF13463.6 EMT50869.1 - 0.00045 20.7 0.0 0.0012 19.3 0.0 1.7 2 0 0 2 2 1 1 Winged helix DNA-binding domain GntR PF00392.21 EMT50869.1 - 0.00081 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 EMT50869.1 - 0.00086 19.1 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PuR_N PF09182.10 EMT50869.1 - 0.0026 17.7 0.3 0.011 15.6 0.3 1.9 1 1 0 1 1 1 1 Bacterial purine repressor, N-terminal RP-C PF03428.13 EMT50869.1 - 0.0034 17.0 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Replication protein C N-terminal domain DUF4423 PF14394.6 EMT50869.1 - 0.0077 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) FeoC PF09012.10 EMT50869.1 - 0.012 15.7 0.6 0.038 14.0 0.0 2.1 2 1 0 2 2 2 0 FeoC like transcriptional regulator HTH_3 PF01381.22 EMT50869.1 - 0.02 15.0 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix Linker_histone PF00538.19 EMT50869.1 - 0.02 15.2 1.3 0.034 14.5 0.1 1.9 2 0 0 2 2 2 0 linker histone H1 and H5 family YdaS_antitoxin PF15943.5 EMT50869.1 - 0.029 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_34 PF13601.6 EMT50869.1 - 0.035 14.3 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain YjcQ PF09639.10 EMT50869.1 - 0.052 13.8 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 YjcQ protein HTH_36 PF13730.6 EMT50869.1 - 0.058 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 EMT50869.1 - 0.076 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Phage_rep_O PF04492.13 EMT50869.1 - 0.11 13.1 0.0 0.38 11.4 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage replication protein O HTH_AraC PF00165.23 EMT50869.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 2 0 0 2 2 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_10 PF04967.12 EMT50869.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain FTH PF01827.27 EMT50870.1 - 0.0047 16.7 0.3 0.0053 16.6 0.3 1.1 1 0 0 1 1 1 1 FTH domain Thioredoxin_3 PF13192.6 EMT50871.1 - 0.00082 19.4 0.5 0.0026 17.8 0.4 2.0 1 1 0 1 1 1 1 Thioredoxin domain ATPgrasp_YheCD PF14398.6 EMT50873.1 - 5.1e-52 176.7 0.5 6.9e-52 176.2 0.5 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 EMT50873.1 - 0.00013 22.0 0.1 0.19 11.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_ST PF14397.6 EMT50873.1 - 0.0038 16.5 0.1 0.57 9.4 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 EMT50873.1 - 0.028 14.0 0.3 0.11 12.1 0.3 2.0 1 1 0 1 1 1 0 RimK-like ATP-grasp domain CP_ATPgrasp_2 PF14403.6 EMT50873.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.4 2 0 0 2 2 2 0 Circularly permuted ATP-grasp type 2 GSH-S_ATP PF02955.16 EMT50873.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain GTP_EFTU_D3 PF03143.17 EMT50875.1 - 0.023 15.0 0.0 0.29 11.4 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu C-terminal domain SNARE_assoc PF09335.11 EMT50878.1 - 1.2e-17 64.5 5.5 1.2e-17 64.5 5.5 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein UPF0239 PF06783.11 EMT50878.1 - 0.26 11.5 0.1 0.58 10.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) PNP_UDP_1 PF01048.20 EMT50879.1 - 9.4e-41 139.6 0.1 1.1e-40 139.4 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily GDP_Man_Dehyd PF16363.5 EMT50880.1 - 8.2e-65 219.4 0.1 2.5e-64 217.8 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMT50880.1 - 1.3e-61 208.1 0.0 1.6e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMT50880.1 - 9.9e-24 83.8 0.1 1.6e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EMT50880.1 - 3.2e-23 82.3 0.1 9.7e-23 80.7 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EMT50880.1 - 5.7e-20 71.6 1.0 8.4e-19 67.8 1.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EMT50880.1 - 4.9e-16 58.7 0.9 2.2e-11 43.4 0.0 2.7 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EMT50880.1 - 4e-07 30.1 0.0 6.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMT50880.1 - 2.2e-05 24.1 0.8 9.5e-05 22.1 0.3 2.0 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.14 EMT50880.1 - 0.0016 18.1 0.1 0.1 12.1 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.25 EMT50880.1 - 0.0057 16.1 1.6 0.046 13.2 1.6 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT50880.1 - 0.0064 16.4 1.2 0.13 12.2 1.0 2.7 1 1 1 2 2 2 1 KR domain 3HCDH_N PF02737.18 EMT50880.1 - 0.019 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EMT50880.1 - 0.063 13.8 0.1 0.14 12.8 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMT50880.1 - 0.073 13.3 0.6 0.33 11.2 0.5 2.1 1 1 0 1 1 1 0 TrkA-N domain Glyco_trans_4_4 PF13579.6 EMT50880.1 - 0.16 12.4 0.5 0.28 11.6 0.2 1.6 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Epimerase PF01370.21 EMT50881.1 - 1.4e-58 198.3 0.0 3.1e-58 197.1 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMT50881.1 - 8.5e-57 193.0 0.0 1e-56 192.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMT50881.1 - 7.4e-21 74.4 0.0 1.2e-19 70.4 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EMT50881.1 - 2.1e-20 73.1 0.0 9.7e-14 51.2 0.0 2.0 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EMT50881.1 - 1.6e-17 63.5 0.0 1.7e-10 40.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EMT50881.1 - 1.7e-10 40.5 0.0 2.3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EMT50881.1 - 1.8e-09 37.8 0.0 2.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMT50881.1 - 3.4e-07 30.1 0.0 5.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EMT50881.1 - 1.3e-05 24.8 0.0 2.8e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMT50881.1 - 0.024 14.5 0.1 0.052 13.5 0.1 1.5 1 1 0 1 1 1 0 KR domain TrkA_N PF02254.18 EMT50881.1 - 0.062 13.6 0.0 0.18 12.1 0.0 1.9 2 1 0 2 2 2 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EMT50881.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EMT50882.1 - 2.5e-42 144.6 0.0 5.4e-42 143.5 0.0 1.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EMT50882.1 - 1.4e-30 105.3 0.0 2.6e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EMT50882.1 - 1.1e-18 67.5 0.0 4.3e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 EMT50882.1 - 1.9e-05 24.9 0.0 8.1e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EMT50882.1 - 0.00085 19.2 0.1 0.0063 16.4 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EMT50882.1 - 0.0024 17.3 0.0 0.48 9.8 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EMT50882.1 - 0.13 12.5 0.0 0.4 11.0 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 EMT50882.1 - 0.2 11.6 0.0 0.81 9.7 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glycos_transf_1 PF00534.20 EMT50883.1 - 1.1e-33 116.2 0.0 1.9e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT50883.1 - 5e-26 91.7 0.0 9.9e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT50883.1 - 8.4e-19 68.2 0.1 1.4e-18 67.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EMT50883.1 - 5.6e-15 56.1 0.0 1.2e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EMT50883.1 - 2.8e-09 37.3 0.0 6.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EMT50883.1 - 1.5e-06 28.1 0.2 2.5e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain LCAT PF02450.15 EMT50883.1 - 0.027 13.6 0.1 0.038 13.2 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Glycos_transf_2 PF00535.26 EMT50885.1 - 3.8e-19 69.1 0.0 6.3e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMT50885.1 - 2.9e-09 37.2 0.0 4.4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EMT50885.1 - 8.2e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EMT50885.1 - 0.011 16.2 0.0 0.025 15.1 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 Osmo_MPGsynth PF09488.10 EMT50885.1 - 0.087 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Glycos_transf_2 PF00535.26 EMT50886.1 - 1.6e-15 57.3 0.0 2.4e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMT50886.1 - 7.3e-07 29.3 0.0 8.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EMT50886.1 - 0.00052 19.6 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Peptidase_S11 PF00768.20 EMT50887.1 - 5.1e-55 186.5 0.1 7.1e-55 186.1 0.1 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 EMT50887.1 - 1.4e-06 28.1 0.0 2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 EMT50887.1 - 0.00018 20.4 0.0 0.009 14.8 0.0 2.2 1 1 1 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family DUF1958 PF09211.10 EMT50887.1 - 0.073 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) RelA_SpoT PF04607.17 EMT50888.1 - 3.2e-33 114.5 0.4 1.2e-32 112.7 0.5 1.8 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins Peptidase_M23 PF01551.22 EMT50889.1 - 4.1e-31 107.0 1.4 6.1e-31 106.5 0.9 1.6 2 0 0 2 2 2 1 Peptidase family M23 NB-LRR PF12061.8 EMT50889.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Late blight resistance protein R1 SASP PF00269.20 EMT50891.1 - 6.3e-24 83.8 0.0 7.5e-24 83.5 0.0 1.1 1 0 0 1 1 1 1 Small, acid-soluble spore proteins, alpha/beta type 5_3_exonuc_N PF02739.16 EMT50892.1 - 2.1e-45 154.5 0.0 2.9e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 EMT50892.1 - 5.6e-32 110.2 0.0 1.1e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 EMT50892.1 - 0.024 14.8 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 EMT50892.1 - 0.052 14.2 0.0 0.23 12.1 0.0 2.1 1 1 0 1 1 1 0 Helix-hairpin-helix domain HHH PF00633.23 EMT50892.1 - 0.071 13.0 0.1 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif OmdA PF13376.6 EMT50893.1 - 0.00023 21.1 0.4 0.00036 20.5 0.4 1.5 1 1 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated VWA_2 PF13519.6 EMT50894.1 - 4.3e-05 24.1 0.4 0.00094 19.8 0.0 2.9 2 1 0 2 2 2 1 von Willebrand factor type A domain AAA_5 PF07728.14 EMT50895.1 - 1.6e-25 89.7 0.0 3.4e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_8 PF17868.1 EMT50895.1 - 4.1e-21 74.7 0.4 5e-20 71.2 0.0 2.6 2 0 0 2 2 2 1 AAA lid domain AAA_3 PF07726.11 EMT50895.1 - 7e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT50895.1 - 0.00053 20.4 0.1 0.0013 19.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EMT50895.1 - 0.0011 19.3 0.0 0.0048 17.3 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EMT50895.1 - 0.0086 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EMT50895.1 - 0.017 14.5 0.1 0.068 12.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MCM PF00493.23 EMT50895.1 - 0.039 13.0 0.0 0.28 10.2 0.0 1.9 1 1 0 2 2 2 0 MCM P-loop domain Sigma54_activat PF00158.26 EMT50895.1 - 0.051 13.3 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.13 EMT50895.1 - 0.063 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 EMT50895.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TRIQK PF15168.6 EMT50896.1 - 0.25 11.2 2.2 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family 40S_S4_C PF16121.5 EMT50897.1 - 0.0088 15.7 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus UPF0061 PF02696.14 EMT50898.1 - 1.2e-123 413.4 0.0 1.5e-123 413.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family COX5A PF02284.16 EMT50898.1 - 0.069 13.2 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va SMI1_KNR4 PF09346.10 EMT50899.1 - 1.1e-30 106.8 0.1 1.9e-30 106.0 0.1 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) LRR_4 PF12799.7 EMT50899.1 - 2.2e-22 78.7 8.9 1.6e-06 28.3 0.1 5.6 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMT50899.1 - 1.6e-13 50.2 5.7 0.00021 21.0 0.1 5.4 2 1 4 6 6 6 4 Leucine rich repeat SUKH_6 PF14568.6 EMT50899.1 - 7.9e-09 36.0 0.1 1.4e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall LRR_6 PF13516.6 EMT50899.1 - 0.0001 22.0 6.8 38 4.7 0.0 6.6 7 0 0 7 7 7 0 Leucine Rich repeat LRR_9 PF14580.6 EMT50899.1 - 0.00037 20.0 1.7 0.039 13.4 0.0 3.3 1 1 2 4 4 4 2 Leucine-rich repeat SUKH_5 PF14567.6 EMT50899.1 - 0.00063 19.5 0.5 0.0088 15.8 0.1 2.2 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall LRR_1 PF00560.33 EMT50899.1 - 0.074 13.6 7.4 20 6.2 0.0 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat Lactamase_B PF00753.27 EMT50900.1 - 3.7e-17 63.0 0.1 1e-16 61.6 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMT50900.1 - 9.2e-05 22.0 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_5 PF14597.6 EMT50900.1 - 0.003 17.1 0.0 0.0067 15.9 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EMT50900.1 - 0.088 12.2 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Methyltransf_11 PF08241.12 EMT50901.1 - 7.6e-25 87.4 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT50901.1 - 1.1e-22 80.6 0.0 1.5e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT50901.1 - 3.9e-17 62.5 0.0 5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT50901.1 - 4.9e-17 62.3 0.0 6.3e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT50901.1 - 8.2e-16 58.6 0.0 1.1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT50901.1 - 2.4e-13 50.0 0.0 3.5e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EMT50901.1 - 2.1e-09 37.1 0.0 3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EMT50901.1 - 5.3e-08 32.1 0.0 8.7e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EMT50901.1 - 1e-06 28.2 0.0 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EMT50901.1 - 2.2e-05 24.0 0.0 3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 EMT50901.1 - 6e-05 22.8 0.0 0.00012 21.7 0.0 1.4 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 EMT50901.1 - 0.00077 20.5 0.0 0.0012 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EMT50901.1 - 0.001 18.6 0.0 0.0066 15.9 0.0 2.2 1 1 1 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 EMT50901.1 - 0.0026 17.9 0.0 0.007 16.5 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 EMT50901.1 - 0.0029 17.2 0.0 0.004 16.8 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EMT50901.1 - 0.0067 16.4 0.0 0.0092 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMT50901.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 EMT50901.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 EMT50901.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB N6_N4_Mtase PF01555.18 EMT50901.1 - 0.021 14.5 0.0 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 DNA methylase Methyltransf_18 PF12847.7 EMT50901.1 - 0.031 14.2 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Csm1_N PF18504.1 EMT50901.1 - 0.055 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain Methyltransf_8 PF05148.15 EMT50901.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase Mor PF08765.11 EMT50902.1 - 7.4e-09 35.6 1.5 1.6e-07 31.3 1.5 2.0 1 1 0 1 1 1 1 Mor transcription activator family Baculo_LEF-11 PF06385.12 EMT50902.1 - 0.05 14.1 0.4 0.16 12.5 0.4 1.9 1 1 0 1 1 1 0 Baculovirus LEF-11 protein DUF433 PF04255.14 EMT50902.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) MFS_1 PF07690.16 EMT50903.1 - 8.9e-34 117.0 56.2 2.6e-23 82.5 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 EMT50903.1 - 0.00015 20.2 5.8 0.00015 20.2 5.8 1.9 2 0 0 2 2 2 1 BT1 family MFS_4 PF06779.14 EMT50903.1 - 0.0032 16.8 38.1 0.0053 16.1 38.1 1.4 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EMT50903.1 - 1.8 6.7 10.4 0.077 11.3 0.7 2.9 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TetR_N PF00440.23 EMT50904.1 - 1.4e-14 53.6 0.1 2.4e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 EMT50904.1 - 0.00025 21.3 0.1 0.0079 16.5 0.0 2.2 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 EMT50904.1 - 0.0021 18.2 0.0 0.0054 16.9 0.0 1.6 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_13 PF16925.5 EMT50904.1 - 0.0061 16.5 0.1 0.016 15.2 0.0 1.7 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Lipid_DES PF08557.10 EMT50904.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) TetR_C_17 PF17922.1 EMT50904.1 - 0.029 14.4 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 EMT50904.1 - 0.047 13.9 0.6 0.42 10.9 0.1 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_25 PF17933.1 EMT50904.1 - 0.061 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4261 PF14080.6 EMT50905.1 - 6.8e-25 87.0 0.0 1.3e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4261) Tiam_CC_Ex PF18385.1 EMT50905.1 - 0.0061 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain AHSA1 PF08327.11 EMT50906.1 - 7.4e-12 45.6 0.4 8.4e-12 45.4 0.4 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Metallophos PF00149.28 EMT50907.1 - 0.011 16.2 0.0 0.014 15.9 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMT50907.1 - 0.04 14.1 0.0 0.041 14.1 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Desulfoferrod_N PF06397.12 EMT50907.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain HTH_18 PF12833.7 EMT50909.1 - 1.5e-19 70.0 0.1 3e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EMT50909.1 - 8.1e-06 25.8 0.0 0.00053 20.0 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family PqqA PF08042.11 EMT50909.1 - 0.15 12.2 0.3 0.57 10.3 0.1 2.0 2 0 0 2 2 2 0 PqqA family MFS_1 PF07690.16 EMT50910.1 - 3.2e-45 154.6 77.1 6.8e-38 130.5 51.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_20 PF12840.7 EMT50911.1 - 1.7e-12 47.2 0.1 2.4e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EMT50911.1 - 2.6e-12 46.4 0.2 3.9e-12 45.8 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 EMT50911.1 - 0.00013 21.8 0.1 0.00025 20.9 0.1 1.4 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 EMT50911.1 - 0.0027 17.6 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 EMT50911.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EMT50911.1 - 0.031 13.8 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 EMT50911.1 - 0.045 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Rrf2 PF02082.20 EMT50911.1 - 0.053 13.9 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_28 PF13518.6 EMT50911.1 - 0.054 13.6 0.0 0.093 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_12 PF08461.10 EMT50911.1 - 0.064 13.2 0.7 1.3 9.0 0.7 2.2 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain RP-C PF03428.13 EMT50911.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_45 PF14947.6 EMT50911.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix UPF0122 PF04297.14 EMT50911.1 - 0.14 12.4 0.1 0.33 11.2 0.0 1.6 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like AHSA1 PF08327.11 EMT50912.1 - 5.2e-17 62.2 0.1 6.6e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EMT50912.1 - 1.6e-06 28.5 0.2 2.2e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport T2SSM PF04612.12 EMT50913.1 - 0.00018 21.6 0.4 0.00023 21.2 0.4 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M Calc_CGRP_IAPP PF00214.19 EMT50913.1 - 0.0019 18.5 0.2 0.0022 18.3 0.2 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family Serinc PF03348.15 EMT50913.1 - 0.0033 16.4 0.2 0.0036 16.3 0.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Peptidase_S49_N PF08496.10 EMT50913.1 - 0.0036 17.4 2.9 0.0043 17.1 2.9 1.0 1 0 0 1 1 1 1 Peptidase family S49 N-terminal EMC3_TMCO1 PF01956.16 EMT50913.1 - 0.005 16.6 2.5 0.0054 16.5 2.5 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF4834 PF16118.5 EMT50913.1 - 0.0056 17.6 0.2 0.0077 17.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) TMEM208_SND2 PF05620.11 EMT50913.1 - 0.012 15.4 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF4446 PF14584.6 EMT50913.1 - 0.012 15.6 2.1 0.015 15.2 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Connexin PF00029.19 EMT50913.1 - 0.013 15.3 0.4 0.015 15.1 0.4 1.0 1 0 0 1 1 1 0 Connexin RIC3 PF15361.6 EMT50913.1 - 0.032 14.6 3.5 0.044 14.2 3.5 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 RecA PF00154.21 EMT50913.1 - 0.037 13.5 0.1 0.043 13.3 0.1 1.0 1 0 0 1 1 1 0 recA bacterial DNA recombination protein DUF4665 PF15679.5 EMT50913.1 - 0.056 14.1 6.6 0.07 13.8 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) Roughex PF06020.11 EMT50913.1 - 0.063 12.4 2.1 0.068 12.3 2.1 1.0 1 0 0 1 1 1 0 Drosophila roughex protein YMF19 PF02326.15 EMT50913.1 - 0.067 14.0 0.1 0.079 13.7 0.1 1.1 1 0 0 1 1 1 0 Plant ATP synthase F0 zf-ZPR1 PF03367.13 EMT50913.1 - 0.082 12.8 2.4 0.086 12.7 2.4 1.0 1 0 0 1 1 1 0 ZPR1 zinc-finger domain SID-1_RNA_chan PF13965.6 EMT50913.1 - 0.11 10.8 0.3 0.13 10.7 0.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 60KD_IMP PF02096.20 EMT50913.1 - 0.12 12.2 2.6 0.14 12.0 2.6 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein Nucleoside_tran PF01733.18 EMT50913.1 - 0.13 11.6 0.6 0.15 11.4 0.6 1.0 1 0 0 1 1 1 0 Nucleoside transporter CLN3 PF02487.17 EMT50913.1 - 0.15 11.1 0.3 0.16 11.0 0.3 1.0 1 0 0 1 1 1 0 CLN3 protein Ureide_permease PF07168.11 EMT50913.1 - 0.15 10.8 0.1 0.16 10.7 0.1 1.0 1 0 0 1 1 1 0 Ureide permease TIP120 PF08623.10 EMT50913.1 - 0.17 11.6 4.2 0.19 11.5 4.2 1.1 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) DUF2254 PF10011.9 EMT50913.1 - 0.17 10.6 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) AAA_23 PF13476.6 EMT50913.1 - 3.6 8.0 12.1 4.1 7.9 12.1 1.0 1 0 0 1 1 1 0 AAA domain SseC PF04888.12 EMT50913.1 - 9.2 5.8 10.6 11 5.6 10.6 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Acetyltransf_3 PF13302.7 EMT50914.1 - 2.8e-05 24.8 0.0 3.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3669 PF12417.8 EMT50914.1 - 0.039 14.1 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 Zinc finger protein Methyltransf_25 PF13649.6 EMT50916.1 - 2.1e-08 34.7 0.0 5e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT50916.1 - 2.6e-06 27.3 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT50916.1 - 9.3e-06 26.2 0.0 4.3e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT50916.1 - 0.1 13.3 0.0 0.29 11.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EMT50916.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EMT50916.1 - 0.15 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DinB PF05163.12 EMT50917.1 - 3.5e-28 98.7 0.1 3.9e-28 98.5 0.1 1.0 1 0 0 1 1 1 1 DinB family DinB_2 PF12867.7 EMT50917.1 - 1.8e-13 51.1 0.0 2.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 EMT50917.1 - 2.5e-07 31.2 0.2 3.4e-06 27.6 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF664) DUF2268 PF10026.9 EMT50917.1 - 0.066 12.8 0.1 0.095 12.3 0.1 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) HATPase_c PF02518.26 EMT50918.1 - 1e-22 80.7 0.1 2e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT50918.1 - 1.3e-16 60.3 0.2 5.6e-16 58.3 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EMT50918.1 - 6.9e-15 55.1 0.0 2e-14 53.7 0.0 1.7 2 0 0 2 2 1 1 PAS fold PAS PF00989.25 EMT50918.1 - 3.6e-13 49.5 0.0 8.2e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EMT50918.1 - 1.6e-11 44.5 0.0 2.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EMT50918.1 - 3.7e-10 40.0 0.0 8.8e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 EMT50918.1 - 6e-05 22.9 0.1 0.00012 22.0 0.1 1.5 1 0 0 1 1 1 1 GHKL domain PAS_8 PF13188.7 EMT50918.1 - 0.00037 20.4 0.0 0.00092 19.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 EMT50918.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT50918.1 - 0.067 13.2 0.1 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain PAS_11 PF14598.6 EMT50918.1 - 0.12 12.5 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 PAS domain DUF2294 PF10057.9 EMT50919.1 - 3.6e-27 94.7 2.9 5.3e-20 71.6 0.1 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2294) DUF2294 PF10057.9 EMT50920.1 - 4.3e-25 88.0 0.6 9.2e-17 61.2 0.0 2.3 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2294) APH PF01636.23 EMT50921.1 - 1.7e-25 90.3 0.0 2.4e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family LBR_tudor PF09465.10 EMT50921.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain LepB_N PF18640.1 EMT50921.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 LepB N-terminal domain THB PF18362.1 EMT50921.1 - 0.063 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Tri-helix bundle domain CSD PF00313.22 EMT50922.1 - 1.4e-30 105.0 2.2 1.5e-30 104.8 2.2 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EMT50922.1 - 0.001 18.7 1.0 0.0014 18.2 1.0 1.6 1 1 0 1 1 1 1 Ribonuclease B OB domain CusF_Ec PF11604.8 EMT50922.1 - 0.064 13.2 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF DUF11 PF01345.18 EMT50922.1 - 0.14 12.5 0.0 0.14 12.4 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function DUF11 Inositol_P PF00459.25 EMT50923.1 - 5.6e-67 226.1 0.0 7.4e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Rhodanese PF00581.20 EMT50924.1 - 2.1e-10 41.0 0.1 6e-10 39.6 0.1 1.6 1 1 0 1 1 1 1 Rhodanese-like domain TetR_N PF00440.23 EMT50924.1 - 0.03 14.1 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Nif11 PF07862.11 EMT50924.1 - 0.12 12.7 0.0 0.56 10.6 0.0 2.0 1 1 0 1 1 1 0 Nif11 domain ABG_transport PF03806.13 EMT50925.1 - 1.1e-200 667.2 37.2 1.3e-200 667.0 37.2 1.0 1 0 0 1 1 1 1 AbgT putative transporter family PAS_6 PF08348.11 EMT50926.1 - 3.9e-40 136.3 0.1 5.9e-40 135.7 0.1 1.3 1 0 0 1 1 1 1 YheO-like PAS domain HTH_22 PF13309.6 EMT50926.1 - 2e-22 79.0 0.0 3.2e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_17 PF12728.7 EMT50926.1 - 0.026 14.7 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 EMT50926.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Acetyltransf_19 PF18015.1 EMT50926.1 - 0.13 12.4 0.2 1.5 9.0 0.1 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Amidohydro_1 PF01979.20 EMT50927.1 - 5.8e-56 190.3 0.1 6.7e-56 190.1 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMT50927.1 - 2.4e-15 57.0 4.8 1.7e-12 47.6 0.3 2.3 1 1 1 2 2 2 2 Amidohydrolase family DUF4580 PF15162.6 EMT50927.1 - 0.16 11.5 0.0 0.88 9.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4580) PALP PF00291.25 EMT50928.1 - 2.4e-84 283.2 5.0 2.7e-84 283.0 5.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Lactamase_B_3 PF13483.6 EMT50928.1 - 0.089 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain LpxI_N PF17930.1 EMT50928.1 - 0.12 12.3 1.8 14 5.5 0.1 3.2 2 1 1 3 3 3 0 LpxI N-terminal domain YjgF_endoribonc PF14588.6 EMT50929.1 - 1e-30 106.8 0.0 1.2e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 EMT50929.1 - 3.9e-15 55.9 0.0 4.6e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP CAP PF00188.26 EMT50930.1 - 1.7e-24 87.0 0.9 1.7e-24 87.0 0.9 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF4106 PF13388.6 EMT50930.1 - 0.59 9.3 11.4 0.86 8.8 11.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) adh_short_C2 PF13561.6 EMT50931.1 - 9.8e-71 238.0 1.9 1.1e-70 237.8 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT50931.1 - 1.6e-59 200.7 6.9 1.8e-59 200.5 6.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT50931.1 - 1.9e-13 50.7 1.6 3e-13 50.1 1.6 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMT50931.1 - 0.00012 22.0 1.1 0.00018 21.5 1.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF881 PF05949.12 EMT50931.1 - 0.0052 16.7 0.6 0.0084 16.0 0.2 1.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF881) DUF2840 PF11000.8 EMT50931.1 - 0.035 13.9 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) TetR_C_8 PF14278.6 EMT50932.1 - 5.7e-21 74.6 0.0 2.4e-20 72.6 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator C-terminal region TetR_N PF00440.23 EMT50932.1 - 3.7e-11 42.6 0.0 1.4e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family Glyco_transf_11 PF01531.16 EMT50932.1 - 0.0014 17.9 0.1 0.0024 17.1 0.1 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 11 HTH_Tnp_1_2 PF13022.6 EMT50932.1 - 0.024 14.8 0.2 0.039 14.1 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Homoserine_dh PF00742.19 EMT50933.1 - 3e-45 154.2 0.0 4.8e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EMT50933.1 - 4.2e-11 43.5 0.0 8.8e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EMT50933.1 - 0.0022 17.8 0.1 0.0084 15.8 0.0 2.1 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Gp_dh_N PF00044.24 EMT50933.1 - 0.043 14.1 0.1 0.093 13.1 0.1 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain HTH_Tnp_1 PF01527.20 EMT50933.1 - 0.096 13.0 0.2 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 Transposase Pep_deformylase PF01327.21 EMT50934.1 - 1.3e-43 148.3 0.0 1.6e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Aminotran_1_2 PF00155.21 EMT50935.1 - 7.3e-33 114.2 0.0 1e-32 113.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II EamA PF00892.20 EMT50937.1 - 2.9e-43 147.3 44.1 1.4e-22 80.3 14.6 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EMT50937.1 - 9.9e-06 25.1 22.3 0.00085 18.7 15.6 2.1 1 1 1 2 2 2 2 Triose-phosphate Transporter family DMT_6 PF04342.12 EMT50937.1 - 0.013 15.7 14.2 1.8 8.8 1.7 3.7 3 0 0 3 3 3 0 Putative member of DMT superfamily (DUF486) Acyl_transf_3 PF01757.22 EMT50938.1 - 1.2e-36 126.5 48.6 1.4e-36 126.2 48.6 1.0 1 0 0 1 1 1 1 Acyltransferase family DUF418 PF04235.12 EMT50939.1 - 6.3e-42 143.3 12.7 6.3e-42 143.3 12.7 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF418) Acyl_transf_3 PF01757.22 EMT50939.1 - 0.034 13.2 35.2 0.26 10.3 20.7 3.0 1 1 2 3 3 3 0 Acyltransferase family Ephrin_lbd PF01404.19 EMT50940.1 - 0.059 13.4 0.0 0.091 12.8 0.0 1.3 1 1 0 1 1 1 0 Ephrin receptor ligand binding domain LPAM_1 PF08139.12 EMT50940.1 - 0.75 10.4 2.1 1.2 9.7 2.1 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Branch_AA_trans PF05525.13 EMT50941.1 - 5.5e-142 473.6 32.0 6.8e-142 473.3 32.0 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein TMEM40 PF15817.5 EMT50941.1 - 1.7 8.4 8.6 19 5.1 3.4 3.1 3 0 0 3 3 3 0 Transmembrane protein 40 family Cytochrom_B561 PF03188.16 EMT50942.1 - 0.033 14.3 0.8 0.035 14.2 0.8 1.0 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 BioY PF02632.14 EMT50942.1 - 0.051 13.6 2.3 0.059 13.4 2.3 1.0 1 0 0 1 1 1 0 BioY family VIT1 PF01988.19 EMT50942.1 - 0.091 12.6 2.2 0.096 12.5 2.2 1.0 1 0 0 1 1 1 0 VIT family ABC2_membrane_3 PF12698.7 EMT50942.1 - 0.13 11.3 3.2 0.15 11.2 3.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3043 PF11241.8 EMT50942.1 - 1.8 8.6 3.8 1.9 8.5 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Insulin_TMD PF17870.1 EMT50942.1 - 5.9 7.0 13.6 1.2 9.3 5.8 2.1 1 1 1 2 2 2 0 Insulin receptor trans-membrane segment MFS_1 PF07690.16 EMT50943.1 - 3.5e-21 75.5 18.0 3.7e-21 75.4 18.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 EMT50943.1 - 2.8e-12 45.8 8.6 3.5e-12 45.5 8.6 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 EMT50943.1 - 0.0096 14.8 10.7 0.013 14.4 10.7 1.2 1 0 0 1 1 1 1 MFS_1 like family EI24 PF07264.11 EMT50943.1 - 3.1 8.0 17.1 31 4.7 17.1 2.1 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) MFS_1 PF07690.16 EMT50944.1 - 3e-10 39.6 9.3 3.5e-10 39.3 9.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT50944.1 - 7.9e-05 21.7 14.2 0.00014 20.9 14.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter BT1 PF03092.16 EMT50944.1 - 0.00031 19.1 8.7 0.0004 18.7 8.7 1.1 1 0 0 1 1 1 1 BT1 family MFS_3 PF05977.13 EMT50944.1 - 0.01 14.3 2.7 0.013 14.0 2.7 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector TMCCDC2 PF15844.5 EMT50944.1 - 0.038 13.9 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 LamB_YcsF PF03746.16 EMT50945.1 - 2.3e-102 341.7 0.2 2.6e-102 341.6 0.2 1.0 1 0 0 1 1 1 1 LamB/YcsF family Esterase_phd PF10503.9 EMT50945.1 - 0.013 15.0 0.3 0.82 9.1 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase CT_A_B PF02626.15 EMT50946.1 - 4.9e-98 328.0 0.1 5.7e-98 327.7 0.1 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CT_C_D PF02682.16 EMT50947.1 - 5.6e-75 251.5 0.0 6.6e-75 251.3 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D IclR PF01614.18 EMT50948.1 - 1.8e-38 131.3 0.0 2.5e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EMT50948.1 - 8.9e-11 41.4 0.7 1.9e-10 40.4 0.7 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 EMT50948.1 - 0.00038 20.3 0.1 0.0021 17.9 0.0 2.3 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB DUF2111 PF09884.9 EMT50948.1 - 0.023 14.8 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) PadR PF03551.14 EMT50948.1 - 0.11 12.4 0.1 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family ATPgrasp_YheCD PF14398.6 EMT50949.1 - 4.9e-51 173.4 0.0 5.8e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EMT50949.1 - 1.5e-08 34.2 0.0 0.00014 21.2 0.0 2.1 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp TTL PF03133.15 EMT50949.1 - 1.2e-05 24.7 0.0 0.0089 15.2 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family GSH-S_ATP PF02955.16 EMT50949.1 - 0.0075 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 EMT50949.1 - 0.045 13.8 0.0 0.65 10.0 0.0 2.3 1 1 0 1 1 1 0 ATP-grasp domain Asp_decarbox PF02261.16 EMT50950.1 - 3.4e-45 152.7 0.0 4e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 Aspartate decarboxylase Redoxin PF08534.10 EMT50950.1 - 0.051 13.3 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin Ldh_2 PF02615.14 EMT50951.1 - 4.6e-128 427.1 0.4 5.2e-128 426.9 0.4 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Peptidase_S13 PF02113.15 EMT50952.1 - 3.8e-242 803.7 5.3 3.9e-121 404.9 0.9 2.0 2 0 0 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase2 PF13354.6 EMT50952.1 - 6.4e-10 39.0 2.6 0.0077 15.9 0.1 5.0 4 2 0 4 4 4 3 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 EMT50952.1 - 5.3e-06 26.0 1.4 0.6 9.5 0.3 3.4 3 0 0 3 3 3 3 D-alanyl-D-alanine carboxypeptidase Recombinase PF07508.13 EMT50952.1 - 0.11 12.9 0.0 2.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Recombinase TxDE PF18711.1 EMT50952.1 - 0.14 12.3 0.0 3.2 7.9 0.0 3.2 4 0 0 4 4 4 0 Toxoflavin-degrading enzyme L_lactis_RepB_C PF06430.12 EMT50953.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Lactococcus lactis RepB C-terminus Glycos_transf_1 PF00534.20 EMT50954.1 - 4.7e-37 127.2 0.0 6.9e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT50954.1 - 1.1e-27 97.1 0.0 2.1e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EMT50954.1 - 1.2e-13 51.3 0.0 2.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT50954.1 - 8.3e-06 25.9 1.2 2e-05 24.7 1.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 ABC_sub_bind PF04392.12 EMT50954.1 - 0.026 13.7 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter substrate binding protein NMT1 PF09084.11 EMT50955.1 - 1.3e-64 218.1 0.9 1.6e-64 217.8 0.9 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EMT50955.1 - 6.9e-07 29.2 0.1 1.3e-05 25.1 0.1 2.1 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 EMT50955.1 - 9.3e-06 25.4 0.3 4.3e-05 23.2 0.1 2.1 2 1 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 EMT50955.1 - 0.00036 20.0 0.1 0.00077 18.9 0.1 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DLH PF01738.18 EMT50955.1 - 0.16 11.5 0.0 0.16 11.5 0.0 2.7 4 0 0 4 4 4 0 Dienelactone hydrolase family BPD_transp_1 PF00528.22 EMT50956.1 - 1.8e-29 102.8 10.4 1.8e-29 102.8 10.4 1.4 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.21 EMT50956.1 - 0.012 16.0 0.8 0.012 16.0 0.8 3.2 2 1 0 2 2 2 0 FtsX-like permease family ABC_tran PF00005.27 EMT50957.1 - 2.3e-29 102.7 0.0 3.1e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT50957.1 - 3.5e-05 23.8 0.8 0.016 15.0 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMT50957.1 - 0.00011 22.4 0.1 0.0009 19.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT50957.1 - 0.00079 19.4 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EMT50957.1 - 0.0012 19.3 0.1 0.0018 18.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EMT50957.1 - 0.0018 17.9 0.2 0.0046 16.7 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EMT50957.1 - 0.0045 17.2 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMT50957.1 - 0.0056 16.7 0.0 0.021 14.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 EMT50957.1 - 0.027 13.3 0.3 0.055 12.3 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 EMT50957.1 - 0.1 12.1 0.1 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EMT50957.1 - 0.13 12.2 0.0 0.51 10.2 0.0 2.0 3 0 0 3 3 3 0 NTPase TENA_THI-4 PF03070.16 EMT50958.1 - 2.8e-52 177.6 4.5 3.2e-52 177.4 4.5 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family DUF3102 PF11300.8 EMT50958.1 - 0.018 15.3 0.6 0.018 15.3 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3102) Peptidase_M20 PF01546.28 EMT50959.1 - 8.5e-34 117.1 0.8 1.2e-33 116.6 0.8 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT50959.1 - 6.7e-25 87.1 0.0 1.5e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT50959.1 - 0.022 14.5 0.1 0.85 9.3 0.1 2.2 2 0 0 2 2 2 0 Peptidase family M28 ThiG PF05690.14 EMT50960.1 - 5.2e-107 356.8 0.1 5.8e-107 356.6 0.1 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EMT50960.1 - 8.3e-05 22.2 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein FMN_dh PF01070.18 EMT50960.1 - 0.00016 20.9 0.2 0.00023 20.3 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EMT50960.1 - 0.0021 17.1 0.5 0.003 16.6 0.5 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NanE PF04131.14 EMT50960.1 - 0.0049 16.1 0.2 0.076 12.2 0.1 2.2 1 1 1 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 EMT50960.1 - 0.028 13.5 0.1 0.04 13.1 0.1 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase Dus PF01207.17 EMT50960.1 - 0.043 12.9 0.2 0.11 11.6 0.2 1.6 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) ThiS PF02597.20 EMT50961.1 - 1.1e-16 61.3 0.6 1.2e-16 61.1 0.6 1.0 1 0 0 1 1 1 1 ThiS family TrkA_N PF02254.18 EMT50961.1 - 0.038 14.2 0.2 0.047 13.9 0.2 1.1 1 0 0 1 1 1 0 TrkA-N domain ThiS-like PF14453.6 EMT50961.1 - 0.045 13.8 0.1 0.13 12.3 0.1 1.8 1 1 0 1 1 1 0 ThiS-like ubiquitin Flg_bbr_C PF06429.13 EMT50961.1 - 0.056 13.6 0.2 0.077 13.1 0.2 1.2 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal KapB PF08810.10 EMT50962.1 - 2.1e-41 140.6 0.0 2.5e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Kinase associated protein B DHHA1 PF02272.19 EMT50963.1 - 6.3e-12 46.1 0.3 1.1e-11 45.4 0.3 1.4 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 EMT50963.1 - 2.3e-10 40.4 0.3 6.3e-09 35.8 0.3 2.4 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 EMT50963.1 - 5.8e-10 38.3 0.0 1.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (A) NuA4 PF09340.10 EMT50963.1 - 0.017 15.0 0.6 0.041 13.8 0.6 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 LUC7 PF03194.15 EMT50963.1 - 0.022 14.4 0.6 0.034 13.8 0.6 1.2 1 0 0 1 1 1 0 LUC7 N_terminus OmpH PF03938.14 EMT50963.1 - 0.66 10.3 5.6 1.3 9.4 5.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FliT PF05400.13 EMT50963.1 - 3.2 8.6 12.4 4.6 8.1 5.1 2.7 1 1 1 2 2 2 0 Flagellar protein FliT DUF2203 PF09969.9 EMT50964.1 - 1.5e-37 129.0 0.0 1.7e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) DnaB_bind PF10410.9 EMT50965.1 - 0.0054 16.9 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 DnaB-helicase binding domain of primase Glyco_hydro_18 PF00704.28 EMT50966.1 - 5.5e-24 85.4 0.0 6.9e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EMT50966.1 - 2.1e-22 78.9 0.0 6.3e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 LysM domain DUF4015 PF13200.6 EMT50966.1 - 0.089 11.8 0.0 0.27 10.2 0.0 1.9 1 1 0 1 1 1 0 Putative glycosyl hydrolase domain Thioredoxin PF00085.20 EMT50967.1 - 1.8e-08 34.3 0.0 1.9e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMT50967.1 - 0.033 14.6 0.0 3 8.3 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like domain Redoxin PF08534.10 EMT50967.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 2 0 0 2 2 2 0 Redoxin HTH_30 PF13556.6 EMT50968.1 - 3.8e-20 71.4 1.5 5.5e-20 70.9 1.5 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 EMT50968.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_8 PF02954.19 EMT50968.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_50 PF18024.1 EMT50968.1 - 0.077 12.6 0.8 0.13 11.9 0.8 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2085 PF09858.9 EMT50969.1 - 1.1e-27 96.3 0.7 1.5e-27 95.9 0.7 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2085) Phage_holin_3_6 PF07332.11 EMT50970.1 - 1.4 9.0 8.8 1.6 8.8 8.8 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2244 PF10003.9 EMT50970.1 - 7.2 6.3 6.2 7.9 6.2 6.2 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) ACT PF01842.25 EMT50971.1 - 6.3e-09 35.5 0.1 1.6e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 EMT50971.1 - 1.3e-06 28.9 0.7 4.9e-06 27.1 0.2 2.0 2 0 0 2 2 2 1 ACT domain Polysacc_deac_2 PF04748.13 EMT50971.1 - 0.092 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase tRNA_Me_trans PF03054.16 EMT50973.1 - 9.5e-149 495.0 0.0 1.1e-148 494.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 EMT50973.1 - 1.4e-07 30.9 0.0 3.5e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 NAD synthase ATP_bind_3 PF01171.20 EMT50973.1 - 9.4e-05 22.2 0.0 0.00032 20.5 0.0 1.8 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 EMT50973.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 EMT50973.1 - 0.00021 20.9 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 EMT50973.1 - 0.0021 17.6 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 EMT50973.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF3592 PF12158.8 EMT50973.1 - 0.057 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Arginosuc_synth PF00764.19 EMT50973.1 - 0.1 11.9 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase FlaG PF03646.15 EMT50973.1 - 0.15 12.2 0.2 0.34 11.1 0.2 1.5 1 0 0 1 1 1 0 FlaG protein FlgM PF04316.13 EMT50974.1 - 0.0073 16.6 3.8 1.8 9.0 1.1 2.2 2 0 0 2 2 2 2 Anti-sigma-28 factor, FlgM DUF2004 PF09406.10 EMT50974.1 - 0.0086 16.4 1.8 0.0099 16.2 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2004) Cortex-I_coil PF09304.10 EMT50974.1 - 0.028 14.6 4.8 0.031 14.5 4.8 1.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil YtxH PF12732.7 EMT50974.1 - 0.036 14.6 3.3 0.15 12.6 3.3 1.8 1 1 0 1 1 1 0 YtxH-like protein TetR_C_24 PF17932.1 EMT50974.1 - 0.041 14.1 1.8 0.042 14.1 1.8 1.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Alg14 PF08660.11 EMT50974.1 - 0.14 12.1 0.4 0.17 11.8 0.4 1.1 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like ING PF12998.7 EMT50974.1 - 0.18 12.4 5.5 0.2 12.3 5.5 1.1 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding THOC7 PF05615.13 EMT50974.1 - 0.74 10.1 10.1 5.1 7.4 10.1 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 DUF952 PF06108.12 EMT50975.1 - 1.7e-21 76.0 0.0 2e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Speriolin_C PF15059.6 EMT50976.1 - 0.0068 16.5 0.0 0.0072 16.5 0.0 1.0 1 0 0 1 1 1 1 Speriolin C-terminus Intg_mem_TP0381 PF09529.10 EMT50977.1 - 1.1e-58 198.4 23.9 1.2e-58 198.2 23.9 1.0 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) DUF2070 PF09843.9 EMT50977.1 - 7.6 4.7 16.5 9.7 4.3 16.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YjbR PF04237.13 EMT50978.1 - 9.3e-12 45.3 0.0 1.2e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 YjbR PHAT PF09246.10 EMT50979.1 - 0.17 11.7 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 PHAT Hydrolase_4 PF12146.8 EMT50981.1 - 7.7e-13 48.3 0.0 1.7e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMT50981.1 - 3.4e-11 43.3 0.0 3.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMT50981.1 - 6.9e-10 39.9 0.8 8.3e-10 39.6 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EMT50981.1 - 0.0055 16.9 0.0 0.015 15.4 0.0 1.8 1 1 1 2 2 2 1 Thioesterase domain Peptidase_S9 PF00326.21 EMT50981.1 - 0.027 14.0 0.0 0.07 12.6 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 EMT50981.1 - 0.061 13.5 0.0 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein Abhydrolase_5 PF12695.7 EMT50981.1 - 0.067 13.0 0.0 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EMT50981.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Inositol_P PF00459.25 EMT50981.1 - 0.13 11.7 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family LIDHydrolase PF10230.9 EMT50981.1 - 0.14 11.6 0.0 0.33 10.5 0.0 1.5 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase YjbR PF04237.13 EMT50983.1 - 1.1e-26 93.1 0.0 1.4e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 YjbR Mur_ligase_C PF02875.21 EMT50985.1 - 0.00078 19.7 0.1 0.0057 16.9 0.0 2.4 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain CDC45 PF02724.14 EMT50985.1 - 3.2 5.9 10.3 4.8 5.4 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein PAH PF02671.21 EMT50986.1 - 0.045 13.9 0.1 0.43 10.8 0.1 2.0 1 1 0 1 1 1 0 Paired amphipathic helix repeat Band_7 PF01145.25 EMT50987.1 - 1.6e-30 106.4 10.1 2.2e-30 106.0 10.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EMT50987.1 - 0.00035 20.3 0.3 0.00066 19.4 0.3 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family DUF737 PF05300.11 EMT50987.1 - 0.0069 16.8 5.6 0.0082 16.5 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) Phage_GP20 PF06810.11 EMT50987.1 - 0.052 13.3 9.5 0.06 13.2 5.8 2.5 1 1 2 3 3 3 0 Phage minor structural protein GP20 Adeno_E3_CR2 PF02439.15 EMT50987.1 - 0.56 10.0 3.9 0.95 9.3 3.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AAA_23 PF13476.6 EMT50987.1 - 3.2 8.2 10.0 4.1 7.9 10.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2512 PF10710.9 EMT50990.1 - 1.9e-17 63.2 7.6 2.2e-17 63.0 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2512) BTP PF05232.12 EMT50990.1 - 0.038 14.0 2.7 0.038 14.0 2.7 2.4 2 1 0 2 2 2 0 Chlorhexidine efflux transporter Polysacc_synt_C PF14667.6 EMT50990.1 - 0.13 12.3 13.3 0.16 12.0 13.3 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain GtrA PF04138.14 EMT50990.1 - 3.6 7.9 13.8 2.9 8.2 2.6 2.0 1 1 1 2 2 2 0 GtrA-like protein MOSC PF03473.17 EMT50991.1 - 0.00076 19.5 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 MOSC domain Acetyltransf_3 PF13302.7 EMT50992.1 - 4.1e-24 85.8 0.0 4.8e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT50992.1 - 1.3e-06 28.6 0.0 1.6e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EMT50992.1 - 0.00027 20.6 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3681 PF12442.8 EMT50993.1 - 0.00029 21.2 1.1 0.00047 20.6 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3681) TipE PF16972.5 EMT50993.1 - 0.57 9.3 1.5 0.7 9.0 1.5 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE DUF4064 PF13273.6 EMT50993.1 - 2.2 8.6 9.1 0.16 12.3 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF2208 PF09973.9 EMT50993.1 - 2.6 7.6 10.0 0.063 12.9 3.4 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2208) ADH_zinc_N PF00107.26 EMT50994.1 - 3.5e-27 94.9 0.1 5.6e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMT50994.1 - 1.7e-21 77.7 0.0 3.4e-21 76.7 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMT50994.1 - 1e-07 31.8 0.1 5.2e-07 29.5 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain YjeF_N PF03853.15 EMT50994.1 - 0.0008 19.3 0.0 0.002 18.1 0.0 1.6 2 0 0 2 2 2 1 YjeF-related protein N-terminus ADH_N_2 PF16884.5 EMT50994.1 - 0.002 18.0 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase TrkA_N PF02254.18 EMT50994.1 - 0.0095 16.2 0.4 0.21 11.9 0.1 1.9 1 1 1 2 2 2 2 TrkA-N domain DUF4024 PF13216.6 EMT50994.1 - 0.057 13.3 0.4 0.7 9.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4024) DUF4952 PF16310.5 EMT50995.1 - 0.21 11.9 0.1 2.9 8.2 0.0 2.7 2 1 2 4 4 4 0 Domian of unknown function (DUF4952) LPAM_1 PF08139.12 EMT50995.1 - 0.37 11.4 1.7 0.8 10.3 1.7 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Cu_amine_oxidN1 PF07833.11 EMT50996.1 - 1.9e-09 37.8 0.0 4.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase N-terminal domain TMEMspv1-c74-12 PF11044.8 EMT50997.1 - 0.03 14.3 9.5 0.03 14.3 9.5 1.7 1 1 1 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein SPC12 PF06645.13 EMT50997.1 - 0.18 11.9 3.6 0.21 11.7 3.6 1.1 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) CrgA PF06781.12 EMT50997.1 - 0.2 11.8 2.5 0.58 10.3 2.8 1.8 1 1 0 1 1 1 0 Cell division protein CrgA MS_channel PF00924.18 EMT50997.1 - 1 8.9 4.4 1.1 8.7 4.4 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel Acetyltransf_1 PF00583.25 EMT50998.1 - 6.1e-12 45.8 0.0 9.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT50998.1 - 2.7e-10 40.3 0.0 3.5e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT50998.1 - 4.8e-08 33.3 0.0 7.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT50998.1 - 0.0028 17.7 0.0 0.017 15.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT50998.1 - 0.0079 16.3 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase V-set_2 PF15910.5 EMT50998.1 - 0.041 14.0 0.1 0.41 10.8 0.0 2.0 1 1 1 2 2 2 0 ICOS V-set domain Acetyltransf_13 PF13880.6 EMT50998.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase FR47 PF08445.10 EMT50998.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein G3P_acyltransf PF02660.15 EMT50999.1 - 3.6e-49 167.0 22.6 4.2e-49 166.7 22.6 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase YtkA PF13115.6 EMT51003.1 - 0.0055 17.3 0.0 0.0081 16.7 0.0 1.3 1 0 0 1 1 1 1 YtkA-like Transposase_mut PF00872.18 EMT51004.1 - 7e-31 107.4 0.4 7.4e-31 107.3 0.4 1.0 1 0 0 1 1 1 1 Transposase, Mutator family SRP68 PF16969.5 EMT51004.1 - 0.017 14.2 0.1 0.017 14.2 0.1 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 TssO PF17561.2 EMT51004.1 - 0.037 14.1 1.8 0.037 14.1 1.8 1.6 2 0 0 2 2 2 0 Type VI secretion system, TssO Laps PF10169.9 EMT51004.1 - 0.072 13.7 2.8 0.12 13.0 2.8 1.3 1 0 0 1 1 1 0 Learning-associated protein Linker_histone PF00538.19 EMT51004.1 - 0.27 11.6 1.6 2.5 8.5 0.1 2.6 3 0 0 3 3 3 0 linker histone H1 and H5 family NosD PF05048.13 EMT51005.1 - 4.9e-38 130.8 11.9 6e-38 130.5 8.8 2.0 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 EMT51005.1 - 1.8e-21 76.6 8.3 1.2e-12 48.0 0.8 2.3 1 1 0 2 2 2 2 Right handed beta helix region HlyD PF00529.20 EMT51005.1 - 0.15 11.9 0.3 0.39 10.6 0.3 1.6 1 0 0 1 1 1 0 HlyD membrane-fusion protein of T1SS NosL PF05573.12 EMT51006.1 - 1.4e-15 57.8 0.8 2.2e-15 57.2 0.8 1.3 1 0 0 1 1 1 1 NosL ABC2_membrane_2 PF12679.7 EMT51007.1 - 2e-14 53.6 22.4 8e-13 48.3 22.4 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 EMT51007.1 - 4.5e-05 23.5 21.2 4.5e-05 23.5 21.2 2.3 1 1 2 3 3 3 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 EMT51007.1 - 0.0035 16.5 40.0 0.0044 16.2 39.4 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 EMT51007.1 - 2.4 7.5 39.2 0.59 9.5 31.5 2.4 1 1 2 3 3 3 0 ABC-2 type transporter ABC_tran PF00005.27 EMT51008.1 - 1e-31 110.3 0.0 2.6e-31 109.0 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EMT51008.1 - 2.1e-17 63.9 0.0 5.6e-11 42.8 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51008.1 - 8.2e-06 25.4 0.2 0.018 14.5 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT51008.1 - 5.8e-05 23.0 0.0 0.018 14.7 0.0 2.1 1 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EMT51008.1 - 0.00075 20.1 0.2 0.00093 19.8 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT51008.1 - 0.0022 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT51008.1 - 0.0022 18.2 0.1 0.0095 16.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMT51008.1 - 0.0046 17.1 0.1 0.014 15.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMT51008.1 - 0.0052 16.5 1.0 0.026 14.3 0.9 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT51008.1 - 0.012 15.5 0.3 0.033 14.1 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 EMT51008.1 - 0.014 14.7 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EMT51008.1 - 0.029 14.7 0.1 0.08 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 EMT51008.1 - 0.043 12.5 0.0 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 EMT51008.1 - 0.077 12.8 0.2 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 MukB N-terminal G-alpha PF00503.20 EMT51008.1 - 0.16 11.1 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA PF00004.29 EMT51008.1 - 0.17 12.3 0.4 2.7 8.4 0.4 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EMT51008.1 - 0.19 10.9 0.2 5.3 6.1 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain TIP41 PF04176.13 EMT51010.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 TIP41-like family Glyoxalase PF00903.25 EMT51011.1 - 2.5e-15 56.8 0.1 3.1e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EMT51011.1 - 6.2e-06 26.9 0.2 8e-06 26.6 0.2 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EMT51011.1 - 3.5e-05 24.0 0.1 0.0083 16.4 0.1 2.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PepSY_2 PF13670.6 EMT51011.1 - 0.018 15.0 0.2 0.029 14.4 0.2 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF2071 PF09844.9 EMT51011.1 - 0.058 13.0 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) HTH_5 PF01022.20 EMT51012.1 - 2.7e-16 59.2 1.1 2.7e-16 59.2 1.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EMT51012.1 - 1.4e-11 44.3 0.0 2.1e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 EMT51012.1 - 3.9e-07 29.5 0.0 6.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 EMT51012.1 - 4e-05 23.5 0.1 7.9e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 EMT51012.1 - 0.00019 21.6 0.0 0.00028 21.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 EMT51012.1 - 0.00021 21.1 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 MarR family DUF2513 PF10711.9 EMT51012.1 - 0.0047 17.2 0.0 0.0057 16.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2513) TFIIE_alpha PF02002.17 EMT51012.1 - 0.018 14.9 0.1 0.025 14.5 0.1 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit DUF4423 PF14394.6 EMT51012.1 - 0.023 14.4 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) TrmB PF01978.19 EMT51012.1 - 0.032 14.1 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 EMT51012.1 - 0.038 14.5 0.1 0.064 13.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain B-block_TFIIIC PF04182.12 EMT51012.1 - 0.04 14.1 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC RP-C PF03428.13 EMT51012.1 - 0.04 13.6 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain Mnd1 PF03962.15 EMT51012.1 - 0.088 13.1 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Mnd1 HTH domain E3_UFM1_ligase PF09743.9 EMT51012.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 BLACT_WH PF17778.1 EMT51012.1 - 0.11 12.5 1.6 0.19 11.7 0.1 1.8 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain GUN4_N PF16416.5 EMT51012.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 ARM-like repeat domain, GUN4-N terminal HTH_micro PF17007.5 EMT51012.1 - 0.16 10.8 0.0 0.17 10.6 0.0 1.0 1 0 0 1 1 1 0 HTH-like DUF4870 PF09685.10 EMT51013.1 - 3.8e-12 46.3 8.0 4.1e-12 46.2 8.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4870) SBF PF01758.16 EMT51013.1 - 0.01 15.6 4.2 0.016 14.9 4.2 1.4 1 1 0 1 1 1 0 Sodium Bile acid symporter family DUF412 PF04217.13 EMT51013.1 - 2.5 8.0 4.8 25 4.8 4.8 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF412 DUF2070 PF09843.9 EMT51013.1 - 3.9 5.7 6.2 4.1 5.6 6.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cation_efflux PF01545.21 EMT51014.1 - 1.1e-28 100.4 13.6 1.3e-28 100.1 13.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EMT51014.1 - 4.7e-08 33.0 0.1 1.3e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter BcrAD_BadFG PF01869.20 EMT51014.1 - 0.031 13.8 0.7 9.4 5.6 0.1 2.7 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family NAD_binding_1 PF00175.21 EMT51015.1 - 4.5e-18 65.9 0.0 9.4e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 EMT51015.1 - 1.3e-14 54.7 0.6 1.6e-12 48.0 0.1 2.4 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 EMT51015.1 - 4e-08 33.5 0.0 1.9e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 EMT51015.1 - 3.2e-05 23.9 0.1 6.1e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 EMT51015.1 - 5.4e-05 23.4 0.0 0.0015 18.7 0.0 2.7 3 0 0 3 3 3 1 Ferric reductase NAD binding domain EamA PF00892.20 EMT51016.1 - 9.3e-39 132.7 30.4 1.8e-19 70.3 10.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EMT51016.1 - 0.0002 20.7 6.9 0.09 12.0 2.3 2.6 2 1 1 3 3 3 2 Purine nucleobase transmembrane transport Phage_holin_3_1 PF05106.12 EMT51016.1 - 0.021 15.2 2.0 1.7 9.1 0.1 2.9 2 1 1 3 3 3 0 Phage holin family (Lysis protein S) UAA PF08449.11 EMT51016.1 - 0.023 13.9 5.7 0.077 12.2 6.0 1.8 1 1 0 1 1 1 0 UAA transporter family TMEM234 PF10639.9 EMT51016.1 - 0.14 12.2 2.5 0.3 11.1 0.4 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 YqfD PF06898.11 EMT51016.1 - 5.2 5.8 4.3 9.8 4.9 0.6 2.1 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD Xan_ur_permease PF00860.20 EMT51017.1 - 1.5e-62 211.5 41.1 1.8e-62 211.2 41.1 1.1 1 0 0 1 1 1 1 Permease family TraL PF07178.11 EMT51017.1 - 0.067 13.7 0.4 0.067 13.7 0.4 4.2 3 2 2 5 5 5 0 TraL protein EamA PF00892.20 EMT51018.1 - 8.8e-24 84.2 42.0 2.1e-12 47.4 20.5 2.0 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 EMT51018.1 - 0.0026 16.8 0.2 0.0057 15.6 0.2 1.7 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like DUF2157 PF09925.9 EMT51018.1 - 5.9 6.7 20.7 0.085 12.6 2.8 3.4 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) HD PF01966.22 EMT51019.1 - 3e-19 69.4 1.6 6.4e-19 68.4 1.6 1.6 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 EMT51019.1 - 1.2e-16 60.7 0.1 3.4e-16 59.3 0.1 1.9 1 0 0 1 1 1 1 HD domain HAMP PF00672.25 EMT51019.1 - 8.9e-12 45.2 0.1 3.4e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 HAMP domain dCache_1 PF02743.18 EMT51019.1 - 1.6e-05 24.8 0.0 5.4e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Cache domain HDOD PF08668.12 EMT51019.1 - 0.054 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 HDOD domain DASH_Dad2 PF08654.10 EMT51019.1 - 0.25 11.8 1.3 0.59 10.6 0.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad2 PAS PF00989.25 EMT51020.1 - 2e-22 79.3 0.1 9.1e-10 38.5 0.0 2.6 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.26 EMT51020.1 - 2.6e-22 79.4 0.1 5.3e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 EMT51020.1 - 5.5e-19 68.4 0.0 5.8e-10 39.4 0.1 2.5 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 EMT51020.1 - 2.3e-15 56.2 0.2 2.7e-07 30.4 0.0 3.1 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 EMT51020.1 - 5.6e-14 52.3 0.0 3.2e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 EMT51020.1 - 1.2e-13 50.9 0.4 4.4e-13 49.1 0.0 2.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 EMT51020.1 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 EMT51020.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_pol3_delta2 PF13177.6 EMT51021.1 - 1.1e-47 161.8 0.0 3.8e-47 160.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 EMT51021.1 - 1.1e-13 51.8 0.0 2.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_gamma3 PF12169.8 EMT51021.1 - 3.8e-13 49.6 2.3 5.2e-13 49.1 0.2 2.3 3 0 0 3 3 3 1 DNA polymerase III subunits gamma and tau domain III RuvB_N PF05496.12 EMT51021.1 - 4.1e-07 29.9 0.1 1e-05 25.3 0.0 2.4 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EMT51021.1 - 2.7e-06 26.8 0.0 0.016 14.4 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_30 PF13604.6 EMT51021.1 - 7.3e-05 22.6 0.5 0.00056 19.7 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EMT51021.1 - 0.00016 21.7 0.0 0.0016 18.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 EMT51021.1 - 0.0005 20.4 0.1 0.0016 18.7 0.1 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 EMT51021.1 - 0.00096 19.4 0.1 0.012 15.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EMT51021.1 - 0.0054 16.8 0.4 3.8 7.5 0.0 3.0 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 EMT51021.1 - 0.0065 16.2 0.0 0.025 14.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 EMT51021.1 - 0.015 14.9 0.1 0.36 10.3 0.1 2.4 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EMT51021.1 - 0.025 15.0 1.9 0.076 13.4 0.1 2.9 3 1 0 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.21 EMT51021.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EMT51021.1 - 0.051 14.1 0.0 0.86 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EMT51021.1 - 0.054 13.5 0.0 0.32 11.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain Glyco_tranf_2_5 PF13712.6 EMT51021.1 - 0.072 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family Rad17 PF03215.15 EMT51021.1 - 0.09 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activat PF00158.26 EMT51021.1 - 0.12 12.1 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain YbaB_DNA_bd PF02575.16 EMT51022.1 - 1.3e-32 111.8 7.2 1.3e-32 111.8 7.2 1.3 2 0 0 2 2 2 1 YbaB/EbfC DNA-binding family DUF1048 PF06304.11 EMT51022.1 - 0.054 13.9 0.8 0.45 11.0 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1048) SIS_2 PF13580.6 EMT51022.1 - 0.059 13.4 0.1 0.068 13.2 0.1 1.1 1 0 0 1 1 1 0 SIS domain DUF4533 PF15047.6 EMT51022.1 - 0.18 11.3 6.9 0.089 12.3 4.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) ERM PF00769.19 EMT51022.1 - 0.83 9.4 6.0 1.1 9.0 6.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LIN52 PF10044.9 EMT51022.1 - 0.85 10.4 3.4 12 6.7 0.1 2.1 1 1 1 2 2 2 0 Retinal tissue protein Toprim_4 PF13662.6 EMT51023.1 - 1.6e-26 92.6 0.0 2.5e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 EMT51023.1 - 4.8e-17 61.2 4.3 7.6e-17 60.6 4.3 1.3 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 EMT51023.1 - 5.5e-08 33.0 0.0 1.5e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Toprim domain HHH PF00633.23 EMT51023.1 - 0.00024 20.8 1.0 0.00043 20.0 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EMT51023.1 - 0.015 15.9 0.2 0.17 12.5 0.0 2.6 2 1 0 2 2 2 0 Helix-hairpin-helix domain HHH_8 PF14716.6 EMT51023.1 - 0.023 15.1 0.0 0.06 13.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain IMS_HHH PF11798.8 EMT51023.1 - 0.14 12.6 0.1 0.43 11.0 0.1 1.8 1 0 0 1 1 1 0 IMS family HHH motif zf-CXXC PF02008.20 EMT51023.1 - 0.3 11.1 2.4 0.47 10.5 2.4 1.2 1 0 0 1 1 1 0 CXXC zinc finger domain CPBP PF02517.16 EMT51024.1 - 5.5e-18 65.1 8.3 5.5e-18 65.1 8.3 2.8 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF2508 PF10704.9 EMT51025.1 - 8.7e-08 32.2 0.0 1.1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2508) Vps23_core PF09454.10 EMT51025.1 - 0.11 12.4 0.1 0.26 11.2 0.0 1.7 1 1 0 1 1 1 0 Vps23 core domain BofA PF07441.11 EMT51026.1 - 5.7e-20 71.3 9.0 7.6e-20 70.9 9.0 1.2 1 0 0 1 1 1 1 SigmaK-factor processing regulatory protein BofA Herpes_pp38 PF04846.13 EMT51026.1 - 0.12 12.3 0.4 0.12 12.3 0.4 1.7 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein Phage_holin_3_6 PF07332.11 EMT51027.1 - 2.5 8.2 12.9 7.4 6.7 4.8 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III UDPG_MGDP_dh_C PF03720.15 EMT51028.1 - 0.0017 18.7 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain PPR_1 PF12854.7 EMT51028.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 PPR repeat Gin PF10764.9 EMT51029.1 - 3.8e-19 68.3 3.9 4.5e-19 68.1 3.9 1.1 1 0 0 1 1 1 1 Inhibitor of sigma-G Gin OKR_DC_1 PF01276.20 EMT51030.1 - 3.8e-81 272.9 0.0 1.5e-80 271.0 0.0 1.7 1 1 1 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 EMT51030.1 - 1.5e-11 44.7 0.1 4.7e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, C-terminal domain Aminotran_1_2 PF00155.21 EMT51030.1 - 2.1e-05 23.9 0.0 4.7e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EMT51030.1 - 3.5e-05 23.2 0.3 4.9e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EMT51030.1 - 0.001 17.7 0.0 0.0015 17.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SepSecS PF05889.13 EMT51030.1 - 0.0031 16.3 0.0 0.0055 15.5 0.0 1.4 2 0 0 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Thymidylate_kin PF02223.17 EMT51031.1 - 7.2e-54 182.3 0.0 8.1e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EMT51031.1 - 1.5e-06 28.6 0.1 2.1e-06 28.1 0.1 1.3 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EMT51031.1 - 0.00018 21.5 0.0 0.00028 20.8 0.0 1.4 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_22 PF13401.6 EMT51031.1 - 0.00079 19.7 0.0 0.0019 18.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 EMT51031.1 - 0.0048 17.3 0.1 0.077 13.4 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EMT51031.1 - 0.0059 17.0 0.1 0.0077 16.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain SKI PF01202.22 EMT51031.1 - 0.014 15.5 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase AAA_33 PF13671.6 EMT51031.1 - 0.014 15.6 0.0 0.047 13.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMT51031.1 - 0.017 15.7 0.0 0.031 14.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EMT51031.1 - 0.021 14.7 0.0 0.051 13.5 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase TIR_2 PF13676.6 EMT51031.1 - 0.044 14.4 0.0 0.15 12.6 0.0 1.9 1 1 0 1 1 1 0 TIR domain PRK PF00485.18 EMT51031.1 - 0.045 13.5 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Ploopntkinase3 PF18751.1 EMT51031.1 - 0.046 13.6 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 EMT51031.1 - 0.055 14.0 0.0 0.081 13.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 EMT51031.1 - 0.059 12.3 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 EMT51031.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 EMT51031.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NTPase TrwB_AAD_bind PF10412.9 EMT51031.1 - 0.12 11.3 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 EMT51031.1 - 0.12 11.7 0.0 0.21 10.8 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 EMT51031.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CdAMP_rec PF06153.11 EMT51032.1 - 9.5e-49 164.1 0.1 1e-48 164.0 0.1 1.0 1 0 0 1 1 1 1 Cyclic-di-AMP receptor DUF327 PF03885.13 EMT51033.1 - 2e-37 128.4 0.9 2.3e-37 128.1 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF327) DNA_pol3_delta2 PF13177.6 EMT51034.1 - 6.9e-61 204.8 0.2 1.3e-60 203.9 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNApol3-delta_C PF09115.10 EMT51034.1 - 3.4e-06 27.5 10.3 9.8e-06 26.1 10.0 2.0 1 1 1 2 2 2 1 DNA polymerase III, delta subunit, C terminal AAA PF00004.29 EMT51034.1 - 2.6e-05 24.6 0.1 6.6e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMT51034.1 - 3.1e-05 24.0 0.0 0.00011 22.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 EMT51034.1 - 0.11 12.4 0.1 0.73 9.7 0.0 2.1 2 1 0 2 2 2 0 Adenylylsulphate kinase PSP1 PF04468.12 EMT51035.1 - 9.3e-34 115.6 5.2 1.5e-33 115.0 5.2 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region YabA PF06156.13 EMT51036.1 - 1.8e-37 128.1 0.8 2.3e-37 127.7 0.8 1.2 1 0 0 1 1 1 1 Initiation control protein YabA HOOK PF05622.12 EMT51036.1 - 0.00035 18.9 1.4 0.00037 18.8 1.4 1.0 1 0 0 1 1 1 1 HOOK protein TSC22 PF01166.18 EMT51036.1 - 0.0015 18.8 0.5 0.0024 18.1 0.5 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family Cep57_CLD_2 PF14197.6 EMT51036.1 - 0.0037 17.3 1.3 2.1 8.5 0.7 2.3 1 1 1 2 2 2 2 Centrosome localisation domain of PPC89 SNAPc19 PF15497.6 EMT51036.1 - 0.0076 16.7 0.5 0.0098 16.3 0.5 1.3 1 0 0 1 1 1 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF3450 PF11932.8 EMT51036.1 - 0.021 14.1 0.5 0.023 14.0 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.12 EMT51036.1 - 0.023 15.1 3.4 0.04 14.4 3.4 1.4 1 1 0 1 1 1 0 Cell division protein ZapB CCDC85 PF10226.9 EMT51036.1 - 0.026 14.2 0.5 0.031 14.0 0.5 1.1 1 0 0 1 1 1 0 CCDC85 family Herpes_BLRF2 PF05812.12 EMT51036.1 - 0.06 13.5 1.8 0.086 13.0 1.6 1.3 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein NRBF2 PF08961.10 EMT51036.1 - 0.14 11.8 2.2 0.17 11.4 1.5 1.4 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator SlyX PF04102.12 EMT51036.1 - 0.19 12.4 1.5 0.25 12.0 1.5 1.2 1 0 0 1 1 1 0 SlyX MTS PF05175.14 EMT51037.1 - 1.8e-12 47.1 0.0 2.5e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EMT51037.1 - 1.6e-06 28.0 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT51037.1 - 4e-06 27.4 0.0 6.6e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EMT51037.1 - 1.4e-05 24.8 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 EMT51037.1 - 2.9e-05 23.7 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EMT51037.1 - 0.00058 19.7 0.0 0.00099 18.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_10 PF05971.12 EMT51037.1 - 0.0017 17.8 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_23 PF13489.6 EMT51037.1 - 0.0026 17.6 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EMT51037.1 - 0.0038 16.9 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 EMT51037.1 - 0.0038 17.2 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 EMT51037.1 - 0.0039 16.5 0.0 0.0054 16.0 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_4 PF02390.17 EMT51037.1 - 0.027 13.9 0.0 0.083 12.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.19 EMT51037.1 - 0.048 13.4 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EMT51037.1 - 0.08 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GIY-YIG PF01541.24 EMT51038.1 - 5.6e-17 61.8 0.3 6.4e-17 61.6 0.3 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain HmuY PF14064.6 EMT51038.1 - 0.079 13.2 0.0 0.089 13.0 0.0 1.2 1 0 0 1 1 1 0 HmuY protein T5orf172 PF10544.9 EMT51038.1 - 0.088 13.4 0.1 0.1 13.2 0.1 1.2 1 0 0 1 1 1 0 T5orf172 domain Unstab_antitox PF09720.10 EMT51038.1 - 0.39 10.8 2.0 0.72 9.9 0.2 2.1 2 0 0 2 2 2 0 Putative addiction module component TP_methylase PF00590.20 EMT51039.1 - 5.2e-28 98.5 0.1 6.5e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MazE_antitoxin PF04014.18 EMT51040.1 - 1.2e-11 44.2 0.0 1.6e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin MraZ PF02381.18 EMT51040.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.4 1 1 0 1 1 1 0 MraZ protein, putative antitoxin-like tRNA-synt_1g PF09334.11 EMT51041.1 - 3.7e-115 384.8 0.0 1.3e-114 383.1 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 EMT51041.1 - 4.6e-30 103.6 0.1 7.5e-30 102.9 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 EMT51041.1 - 3.2e-28 98.4 0.8 2.6e-14 52.4 0.0 4.0 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EMT51041.1 - 7.6e-12 45.2 0.0 8.3e-07 28.6 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EMT51041.1 - 5.4e-07 29.7 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 EMT51041.1 - 0.0017 17.4 0.0 0.1 11.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) DUF2724 PF10893.8 EMT51041.1 - 0.18 11.7 0.5 0.92 9.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2724) TatD_DNase PF01026.21 EMT51042.1 - 1.1e-90 303.4 0.0 1.3e-90 303.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EMT51042.1 - 0.0067 16.2 0.3 0.16 11.8 0.2 2.5 1 1 1 2 2 2 1 Amidohydrolase DUF348 PF03990.14 EMT51043.1 - 1.3e-19 69.7 15.3 3.3e-12 45.9 0.7 4.2 6 0 0 6 6 6 2 G5-linked-Ubiquitin-like domain G5 PF07501.12 EMT51043.1 - 1.2e-18 67.3 5.1 1.2e-18 67.3 5.1 2.1 2 1 0 2 2 2 1 G5 domain 3D PF06725.11 EMT51043.1 - 1.5e-15 57.1 1.7 4.5e-15 55.6 1.0 2.2 2 0 0 2 2 2 1 3D domain DUF4093 PF13331.6 EMT51044.1 - 5e-28 97.4 0.4 1.2e-27 96.2 0.2 1.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4093) Toprim PF01751.22 EMT51044.1 - 9.2e-08 32.2 0.5 5.2e-07 29.8 0.2 2.0 2 0 0 2 2 2 1 Toprim domain Toprim_4 PF13662.6 EMT51044.1 - 1.7e-07 31.6 0.5 3.3e-07 30.7 0.2 1.6 1 1 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 EMT51044.1 - 0.0091 16.3 0.1 0.023 15.0 0.1 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 EMT51044.1 - 0.0097 16.3 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Toprim-like DUF2017 PF09438.10 EMT51044.1 - 0.049 13.5 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) PMBR PF09373.10 EMT51044.1 - 0.12 12.6 0.1 10 6.5 0.0 3.1 2 1 1 3 3 3 0 Pseudomurein-binding repeat RrnaAD PF00398.20 EMT51045.1 - 2.6e-68 230.0 0.0 2.9e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EMT51045.1 - 0.0026 18.4 0.0 0.0045 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT51045.1 - 0.0069 17.0 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EMT51045.1 - 0.084 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) VEG PF06257.11 EMT51046.1 - 2.4e-30 104.4 0.0 2.9e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Biofilm formation stimulator VEG SASP PF00269.20 EMT51047.1 - 3.5e-06 26.9 0.0 5.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Small, acid-soluble spore proteins, alpha/beta type Sun2_CC2 PF18580.1 EMT51047.1 - 0.042 14.1 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 GHMP_kinases_N PF00288.26 EMT51048.1 - 3.7e-12 46.3 0.4 6.8e-12 45.4 0.4 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMT51048.1 - 1.9e-11 44.1 0.0 3.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal PuR_N PF09182.10 EMT51049.1 - 3.4e-30 103.8 0.0 6.9e-30 102.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial purine repressor, N-terminal Pribosyltran PF00156.27 EMT51049.1 - 5.2e-22 78.1 0.4 7.7e-22 77.5 0.4 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ribonuc_L-PSP PF01042.21 EMT51050.1 - 1.2e-46 157.7 0.0 1.3e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.6 EMT51050.1 - 0.045 13.9 0.1 0.061 13.5 0.0 1.5 1 1 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease SpoVG PF04026.12 EMT51051.1 - 3.3e-36 123.3 0.2 3.8e-36 123.1 0.2 1.0 1 0 0 1 1 1 1 SpoVG cobW PF02492.19 EMT51052.1 - 3.1e-45 153.9 0.0 3.9e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EMT51052.1 - 1.2e-16 60.3 0.0 3.1e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 EMT51052.1 - 8.9e-05 22.9 0.1 0.004 17.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.14 EMT51052.1 - 0.00027 20.8 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 EMT51052.1 - 0.00053 19.8 0.2 0.28 10.9 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein SRP54 PF00448.22 EMT51052.1 - 0.00057 19.6 0.5 0.0015 18.2 0.5 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 EMT51052.1 - 0.00082 19.9 0.6 0.0084 16.6 0.1 2.2 2 0 0 2 2 2 1 ABC transporter NTPase_1 PF03266.15 EMT51052.1 - 0.0013 18.7 0.1 0.0044 17.0 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_30 PF13604.6 EMT51052.1 - 0.0023 17.7 0.1 0.0043 16.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EMT51052.1 - 0.0029 16.7 0.0 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EMT51052.1 - 0.0039 17.1 1.0 1.5 8.7 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase TrwB_AAD_bind PF10412.9 EMT51052.1 - 0.0039 16.2 0.1 0.0058 15.6 0.1 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 EMT51052.1 - 0.0056 17.0 0.1 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EMT51052.1 - 0.0068 16.4 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EMT51052.1 - 0.0081 15.5 0.1 0.018 14.3 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 EMT51052.1 - 0.0085 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MeaB PF03308.16 EMT51052.1 - 0.0096 14.9 0.8 0.23 10.4 0.0 2.7 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 EMT51052.1 - 0.01 15.9 0.2 0.021 14.8 0.2 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EMT51052.1 - 0.013 16.1 0.3 0.037 14.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EMT51052.1 - 0.02 14.4 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain KTI12 PF08433.10 EMT51052.1 - 0.029 13.8 0.2 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MMR_HSR1_Xtn PF16897.5 EMT51052.1 - 0.034 14.1 0.2 0.12 12.4 0.2 1.9 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ATPase_2 PF01637.18 EMT51052.1 - 0.036 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DAP3 PF10236.9 EMT51052.1 - 0.051 12.8 0.5 0.084 12.0 0.2 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Thymidylate_kin PF02223.17 EMT51052.1 - 0.051 13.3 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_29 PF13555.6 EMT51052.1 - 0.062 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT51052.1 - 0.069 13.7 0.0 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EMT51052.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EMT51052.1 - 0.078 13.4 0.4 10 6.5 0.2 3.2 2 1 1 3 3 3 0 AAA domain Arf PF00025.21 EMT51052.1 - 0.086 12.3 1.9 1.8 8.0 0.2 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family PIF1 PF05970.14 EMT51052.1 - 0.087 12.0 0.1 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 PIF1-like helicase APS_kinase PF01583.20 EMT51052.1 - 0.089 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 EMT51052.1 - 0.099 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EMT51052.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain CLP1_P PF16575.5 EMT51052.1 - 0.13 12.0 0.1 4.6 7.0 0.0 2.4 2 1 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_28 PF13521.6 EMT51052.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hexapep PF00132.24 EMT51053.1 - 3e-29 99.6 9.1 5.4e-06 25.9 0.5 5.5 3 1 2 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EMT51053.1 - 6.6e-24 85.1 1.5 1.1e-23 84.4 1.5 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EMT51053.1 - 3.3e-23 82.5 0.2 4.8e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase IspD PF01128.19 EMT51053.1 - 8.7e-11 42.0 4.5 2.2e-10 40.6 4.5 1.7 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 EMT51053.1 - 2.6e-08 33.5 10.0 0.0065 16.2 0.5 5.2 4 1 1 5 5 5 3 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 EMT51053.1 - 3.3e-05 23.9 0.0 4.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase CofC PF01983.16 EMT51053.1 - 0.00012 21.4 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Guanylyl transferase CofC like DUF1694 PF07997.11 EMT51053.1 - 0.037 14.1 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) Smr PF01713.21 EMT51053.1 - 0.055 13.8 0.2 0.27 11.6 0.3 2.1 2 0 0 2 2 2 0 Smr domain DUF4350 PF14258.6 EMT51053.1 - 0.097 13.1 0.2 0.44 11.0 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4350) KorB_C PF06613.11 EMT51053.1 - 0.1 12.6 0.0 9.7 6.3 0.0 2.6 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain Pribosyltran_N PF13793.6 EMT51054.1 - 3.8e-51 171.9 0.2 2.3e-50 169.4 0.0 2.2 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EMT51054.1 - 1.6e-26 93.5 7.5 2.6e-25 89.5 2.8 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EMT51054.1 - 7.4e-21 74.3 1.9 1.4e-19 70.1 0.4 2.7 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EMT51054.1 - 0.043 13.2 0.1 0.072 12.5 0.1 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ribosomal_L25p PF01386.19 EMT51055.1 - 1.1e-20 73.9 0.2 5.9e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal L25p family Ribosomal_TL5_C PF14693.6 EMT51055.1 - 5.1e-18 65.2 3.8 8.7e-18 64.5 3.8 1.4 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Pept_tRNA_hydro PF01195.19 EMT51057.1 - 1.6e-62 210.5 0.0 1.8e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF433 PF04255.14 EMT51057.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF433) DUF2757 PF10955.8 EMT51058.1 - 1.3e-18 67.0 0.1 1.4e-18 66.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2757) CarD_CdnL_TRCF PF02559.16 EMT51059.1 - 2.3e-30 105.1 0.6 8.9e-30 103.3 0.6 2.1 1 0 0 1 1 1 1 CarD-like/TRCF domain TRCF PF03461.15 EMT51059.1 - 1.1e-26 93.0 0.4 3.8e-26 91.3 0.1 2.1 2 0 0 2 2 2 1 TRCF domain UvrB_inter PF17757.1 EMT51059.1 - 2.6e-23 82.0 0.0 8e-23 80.4 0.0 2.0 1 0 0 1 1 1 1 UvrB interaction domain Helicase_C PF00271.31 EMT51059.1 - 8.4e-21 74.4 0.3 1.8e-16 60.5 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EMT51059.1 - 4.4e-19 68.9 1.7 3e-18 66.2 0.1 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 EMT51059.1 - 3.1e-09 37.1 0.0 1e-08 35.4 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EMT51059.1 - 7.8e-06 24.8 0.0 2.4e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain AroM PF07302.11 EMT51059.1 - 0.03 13.7 0.0 0.11 11.9 0.0 2.0 1 0 0 1 1 1 0 AroM protein Glyco_tran_WecB PF03808.13 EMT51059.1 - 0.11 12.4 0.0 0.4 10.6 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family AAA_22 PF13401.6 EMT51059.1 - 0.61 10.4 3.1 4.8 7.5 0.3 3.8 5 1 0 5 5 5 0 AAA domain Rotamase_3 PF13616.6 EMT51060.1 - 6e-28 97.7 3.2 4.2e-27 95.0 0.1 3.1 1 1 0 3 3 3 1 PPIC-type PPIASE domain Rotamase PF00639.21 EMT51060.1 - 3.3e-22 79.2 7.1 9.9e-22 77.7 0.1 3.3 2 1 0 3 3 3 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EMT51060.1 - 1.6e-13 51.5 1.3 1.6e-13 51.5 1.3 3.0 3 0 0 3 3 3 1 PPIC-type PPIASE domain Get5_C PF18514.1 EMT51060.1 - 0.1 12.3 0.1 0.29 10.9 0.1 1.8 1 0 0 1 1 1 0 Get5 C-terminal domain DUF4907 PF16250.5 EMT51060.1 - 0.14 12.1 0.5 1.5 8.7 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4907) HJURP_C PF12347.8 EMT51060.1 - 0.22 11.6 1.5 0.94 9.6 0.7 2.3 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat SpoVT_C PF15714.5 EMT51061.1 - 1.9e-46 157.2 0.1 2.6e-46 156.8 0.1 1.2 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor MazE_antitoxin PF04014.18 EMT51061.1 - 8.3e-11 41.6 2.1 1.4e-10 40.8 2.1 1.4 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin PrlF_antitoxin PF15937.5 EMT51061.1 - 0.024 15.1 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin GAF PF01590.26 EMT51061.1 - 0.094 13.3 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 GAF domain Polysacc_synt PF01943.17 EMT51062.1 - 1.3e-35 123.1 13.0 1.3e-35 123.1 13.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 EMT51062.1 - 4.2e-32 111.2 24.0 4.2e-32 111.2 24.0 3.8 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 EMT51062.1 - 2.9e-15 55.8 23.8 1.3e-14 53.7 23.5 2.0 1 1 0 1 1 1 1 Lipid II flippase MurJ MatE PF01554.18 EMT51062.1 - 2.5e-11 43.5 31.1 8.2e-09 35.3 4.6 3.6 3 1 0 3 3 3 2 MatE Polysacc_synt_3 PF13440.6 EMT51062.1 - 0.00026 20.3 18.1 0.0013 18.0 3.4 3.1 2 1 1 3 3 3 3 Polysaccharide biosynthesis protein GtrA PF04138.14 EMT51062.1 - 0.018 15.2 10.6 0.018 15.2 10.6 4.0 3 1 0 3 3 3 0 GtrA-like protein MazG PF03819.17 EMT51063.1 - 1.3e-33 115.0 1.8 3.1e-26 91.3 0.2 3.0 2 1 1 3 3 3 2 MazG nucleotide pyrophosphohydrolase domain TP_methylase PF00590.20 EMT51063.1 - 5.9e-21 75.4 2.0 1.8e-20 73.8 2.0 1.9 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PRA-PH PF01503.17 EMT51063.1 - 7.6e-07 29.5 5.6 0.0017 18.8 0.3 2.9 3 0 0 3 3 3 2 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 EMT51063.1 - 0.002 18.4 0.2 0.48 10.7 0.0 2.8 2 0 0 2 2 2 2 MazG-like family Acetone_carb_G PF08882.11 EMT51063.1 - 0.12 12.5 0.1 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 Acetone carboxylase gamma subunit S4 PF01479.25 EMT51064.1 - 1.2e-09 37.8 0.3 1.7e-09 37.2 0.3 1.3 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EMT51064.1 - 0.051 13.4 0.1 0.12 12.2 0.1 1.8 1 1 0 1 1 1 0 S4 domain NfeD PF01957.18 EMT51064.1 - 0.058 13.8 0.1 0.092 13.1 0.1 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding TPR_2 PF07719.17 EMT51065.1 - 3.4e-17 61.1 15.8 3.3e-05 23.7 1.9 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EMT51065.1 - 4.6e-16 57.6 11.8 1.4e-07 31.2 1.6 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EMT51065.1 - 5.9e-16 57.5 14.0 4.1e-05 23.2 2.2 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMT51065.1 - 1.5e-15 57.5 9.8 1.2e-07 32.2 1.4 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMT51065.1 - 1.6e-12 47.5 7.7 3.1e-05 24.2 1.6 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EMT51065.1 - 2.7e-12 47.1 7.5 3.9e-05 24.2 1.3 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EMT51065.1 - 1.4e-09 38.0 3.6 9e-05 22.5 0.4 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMT51065.1 - 3.9e-09 36.6 9.6 0.048 14.5 0.1 5.0 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMT51065.1 - 2.7e-08 33.6 3.5 0.0034 17.7 0.1 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EMT51065.1 - 1e-07 32.1 14.4 0.00036 21.0 1.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMT51065.1 - 3.6e-07 29.8 5.4 0.0087 16.0 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMT51065.1 - 2e-06 27.9 5.8 0.0005 20.2 0.4 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EMT51065.1 - 4.1e-06 26.2 3.3 0.0028 16.9 0.3 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 EMT51065.1 - 2.9e-05 24.3 4.6 6e-05 23.3 0.6 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat FAT PF02259.23 EMT51065.1 - 4.8e-05 22.7 1.5 6.2e-05 22.4 1.5 1.1 1 0 0 1 1 1 1 FAT domain TPR_11 PF13414.6 EMT51065.1 - 0.0001 21.9 11.0 0.23 11.2 0.1 4.7 3 2 2 5 5 5 3 TPR repeat NARP1 PF12569.8 EMT51065.1 - 0.00019 20.5 7.5 0.0084 15.1 0.4 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 EMT51065.1 - 0.00025 20.8 7.5 0.035 13.8 0.3 2.2 1 1 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 EMT51065.1 - 0.00033 20.4 5.6 0.17 11.8 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Clathrin PF00637.20 EMT51065.1 - 0.00035 20.4 0.8 0.014 15.2 0.1 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS SNAP PF14938.6 EMT51065.1 - 0.0022 17.4 6.0 0.0099 15.3 1.2 2.2 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP DUF3808 PF10300.9 EMT51065.1 - 0.0025 16.6 1.8 0.088 11.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) Sec16_C PF12931.7 EMT51065.1 - 0.0045 16.7 0.7 0.0099 15.6 0.1 1.8 2 0 0 2 2 2 1 Sec23-binding domain of Sec16 PPR PF01535.20 EMT51065.1 - 0.0076 16.4 0.8 1.4 9.4 0.1 3.5 4 0 0 4 4 2 1 PPR repeat HrpB1_HrpK PF09613.10 EMT51065.1 - 0.0086 15.7 0.2 0.043 13.4 0.1 1.9 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_MalT PF17874.1 EMT51065.1 - 0.0096 15.3 1.7 0.87 8.9 0.5 2.4 1 1 1 2 2 2 1 MalT-like TPR region DegV PF02645.16 EMT51065.1 - 0.021 14.2 0.3 0.028 13.8 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 PknG_TPR PF16918.5 EMT51065.1 - 0.032 13.0 0.1 0.088 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat IKKbetaNEMObind PF12179.8 EMT51065.1 - 0.09 12.8 0.5 0.2 11.7 0.1 1.7 2 0 0 2 2 1 0 I-kappa-kinase-beta NEMO binding domain DUF2225 PF09986.9 EMT51065.1 - 0.12 12.1 2.4 0.14 11.9 0.6 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Ubiq-assoc PF09145.10 EMT51065.1 - 0.56 10.2 4.1 0.23 11.5 0.7 2.0 2 0 0 2 2 2 0 Ubiquitin-associated Cu_amine_oxidN1 PF07833.11 EMT51066.1 - 1.5e-17 63.8 5.0 5.8e-12 45.9 0.5 4.5 3 1 1 4 4 4 2 Copper amine oxidase N-terminal domain DUF2808 PF10989.8 EMT51066.1 - 4.9e-06 26.6 9.6 4.8e-05 23.4 0.1 4.8 4 2 1 5 5 5 1 Protein of unknown function (DUF2808) Big_8 PF17961.1 EMT51066.1 - 0.0004 20.5 1.6 0.0004 20.5 1.6 3.9 1 1 0 2 2 2 1 Bacterial Ig domain Cupredoxin_1 PF13473.6 EMT51066.1 - 0.0017 18.4 3.4 0.16 12.1 0.0 4.0 2 1 2 4 4 4 1 Cupredoxin-like domain DUF5065 PF16723.5 EMT51066.1 - 0.018 15.1 0.8 9.5 6.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5065) BcsB PF03170.13 EMT51066.1 - 0.078 11.3 0.2 0.46 8.8 0.5 2.1 2 1 0 2 2 2 0 Bacterial cellulose synthase subunit PapC_N PF13954.6 EMT51066.1 - 0.2 11.7 0.6 31 4.6 0.1 3.6 3 1 1 4 4 4 0 PapC N-terminal domain YabP PF07873.11 EMT51067.1 - 3e-21 75.0 0.4 3.5e-21 74.7 0.4 1.1 1 0 0 1 1 1 1 YabP family Peptidase_C30 PF05409.13 EMT51067.1 - 0.16 11.3 0.0 0.18 11.1 0.0 1.0 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 Spore_YabQ PF09578.10 EMT51068.1 - 3.4e-18 65.6 10.1 3.4e-18 65.6 10.1 2.4 2 1 0 2 2 2 1 Spore cortex protein YabQ (Spore_YabQ) DivIC PF04977.15 EMT51069.1 - 7.2e-17 60.9 0.2 1.1e-16 60.4 0.2 1.3 1 0 0 1 1 1 1 Septum formation initiator ABC_tran_CTD PF16326.5 EMT51069.1 - 0.016 15.5 1.7 0.028 14.6 1.7 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain RNase_Zc3h12a PF11977.8 EMT51069.1 - 0.073 12.8 0.4 0.092 12.5 0.4 1.3 1 1 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain FtsL PF04999.13 EMT51069.1 - 0.081 12.9 0.1 0.13 12.3 0.1 1.4 1 1 0 1 1 1 0 Cell division protein FtsL S1 PF00575.23 EMT51070.1 - 1.3e-18 67.1 1.6 2.1e-18 66.4 1.6 1.2 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.6 EMT51070.1 - 0.0094 16.0 0.1 0.14 12.2 0.1 2.3 1 1 0 1 1 1 1 S1 domain CsrA PF02599.16 EMT51070.1 - 0.01 15.8 0.3 0.016 15.1 0.3 1.3 1 0 0 1 1 1 0 Global regulator protein family POC1 PF10450.9 EMT51070.1 - 0.16 10.9 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 POC1 chaperone SpoIIE PF07228.12 EMT51071.1 - 4.1e-37 128.0 0.3 7.4e-37 127.1 0.3 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EMT51071.1 - 0.0051 16.5 0.0 1.4 8.6 0.0 2.7 1 1 0 1 1 1 1 Protein phosphatase 2C DUF805 PF05656.14 EMT51071.1 - 7.1 7.1 6.2 43 4.6 6.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF485 PF04341.12 EMT51071.1 - 8.5 6.4 8.7 1.3 9.0 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DeoRC PF00455.22 EMT51072.1 - 3.7e-51 173.2 0.2 5.1e-51 172.8 0.2 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EMT51072.1 - 1.9e-17 62.8 0.7 3e-17 62.1 0.7 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_5 PF01022.20 EMT51072.1 - 2.7e-05 23.9 0.3 6.7e-05 22.7 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 EMT51072.1 - 9e-05 22.2 0.2 0.00018 21.2 0.2 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.12 EMT51072.1 - 0.00075 19.4 0.7 0.0015 18.4 0.3 1.7 2 0 0 2 2 2 1 HTH domain GntR PF00392.21 EMT51072.1 - 0.0024 17.5 0.5 0.0051 16.4 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EMT51072.1 - 0.0038 16.8 0.2 0.0079 15.7 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Put_DNA-bind_N PF06971.13 EMT51072.1 - 0.0038 17.2 0.1 0.0077 16.2 0.1 1.5 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus HTH_Crp_2 PF13545.6 EMT51072.1 - 0.0085 16.1 0.7 0.27 11.2 0.3 2.5 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_29 PF13551.6 EMT51072.1 - 0.067 13.2 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Rrf2 PF02082.20 EMT51072.1 - 0.087 13.2 0.2 0.18 12.2 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator PfkB PF00294.24 EMT51073.1 - 1.2e-52 179.1 0.0 1.5e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EMT51073.1 - 6.5e-05 22.4 0.0 9.3e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PTS_EIIA_2 PF00359.22 EMT51074.1 - 7.9e-39 132.8 0.5 1.3e-38 132.1 0.5 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PTS_IIB PF02302.17 EMT51074.1 - 1e-16 61.4 0.5 1e-16 61.4 0.5 1.9 2 0 0 2 2 2 1 PTS system, Lactose/Cellobiose specific IIB subunit Nif11 PF07862.11 EMT51074.1 - 0.008 16.5 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 Nif11 domain PTS-HPr PF00381.19 EMT51075.1 - 2.2e-30 104.7 0.0 2.4e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site PEP-utilizers_C PF02896.18 EMT51076.1 - 8.3e-127 422.3 0.1 1.6e-126 421.4 0.1 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 EMT51076.1 - 1.8e-35 121.6 6.0 7.4e-35 119.6 6.0 2.1 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 EMT51076.1 - 1.5e-25 88.7 0.7 3.4e-25 87.6 0.7 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HpcH_HpaI PF03328.14 EMT51076.1 - 0.00079 18.6 0.0 0.0019 17.4 0.0 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family VWA PF00092.28 EMT51077.1 - 4.9e-12 46.4 0.1 1.5e-06 28.6 0.1 2.4 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 EMT51077.1 - 2.5e-07 31.3 0.1 9.9e-07 29.4 0.0 2.0 3 0 0 3 3 3 1 von Willebrand factor type A domain DUF1194 PF06707.11 EMT51077.1 - 5.8e-05 22.4 1.3 0.0098 15.1 0.1 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1194) VWA_3 PF13768.6 EMT51077.1 - 0.0015 18.5 0.1 0.49 10.3 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain YjeF_N PF03853.15 EMT51077.1 - 0.093 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Pkinase PF00069.25 EMT51078.1 - 3.8e-17 62.5 0.0 5.1e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EMT51078.1 - 4.9e-09 36.5 0.5 0.00028 20.9 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EMT51078.1 - 0.002 17.5 0.0 0.0048 16.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase ThrE PF06738.12 EMT51079.1 - 5.1e-69 232.3 4.4 5.7e-69 232.1 4.4 1.0 1 0 0 1 1 1 1 Putative threonine/serine exporter ThrE_2 PF12821.7 EMT51079.1 - 7.7e-10 39.0 7.9 1.3e-09 38.3 7.9 1.3 1 0 0 1 1 1 1 Threonine/Serine exporter, ThrE ThrE_2 PF12821.7 EMT51080.1 - 2.6e-31 108.4 14.9 3.1e-31 108.2 14.9 1.0 1 0 0 1 1 1 1 Threonine/Serine exporter, ThrE ThrE PF06738.12 EMT51080.1 - 5e-09 35.9 17.8 5.7e-09 35.7 17.8 1.0 1 0 0 1 1 1 1 Putative threonine/serine exporter ATP_bind_3 PF01171.20 EMT51081.1 - 2.1e-48 164.5 0.0 3.8e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 PP-loop family TilS_C PF11734.8 EMT51081.1 - 1.4e-16 59.6 0.6 3.9e-16 58.2 0.6 1.7 1 0 0 1 1 1 1 TilS substrate C-terminal domain TilS PF09179.11 EMT51081.1 - 4.2e-07 30.3 0.1 1.6e-06 28.5 0.1 2.0 1 0 0 1 1 1 1 TilS substrate binding domain B3_4 PF03483.17 EMT51081.1 - 0.008 15.9 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain QueC PF06508.13 EMT51081.1 - 0.0086 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EMT51081.1 - 0.017 13.9 0.0 0.036 12.9 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase NAD_synthase PF02540.17 EMT51081.1 - 0.05 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD synthase Pribosyltran PF00156.27 EMT51082.1 - 1.3e-30 106.1 0.0 1.5e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EMT51082.1 - 0.062 12.7 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Peptidase_M41 PF01434.18 EMT51083.1 - 1.3e-74 250.2 0.2 2.3e-74 249.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EMT51083.1 - 4.9e-46 156.4 0.0 1.1e-45 155.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMT51083.1 - 3.3e-11 42.8 0.2 7e-11 41.8 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EMT51083.1 - 2.4e-08 34.3 4.6 1.4e-05 25.4 0.4 2.8 3 0 0 3 3 2 2 FtsH Extracellular AAA_5 PF07728.14 EMT51083.1 - 1.9e-05 24.7 0.0 0.00025 21.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMT51083.1 - 6.1e-05 23.5 0.3 0.0018 18.7 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 EMT51083.1 - 9.7e-05 21.7 0.1 0.00024 20.4 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 EMT51083.1 - 0.00029 20.6 0.0 0.00082 19.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMT51083.1 - 0.002 18.4 0.1 0.062 13.6 0.1 2.7 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMT51083.1 - 0.0029 17.8 0.0 0.0088 16.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 EMT51083.1 - 0.0075 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EMT51083.1 - 0.014 14.8 0.1 0.03 13.7 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EMT51083.1 - 0.021 15.4 0.2 0.14 12.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EMT51083.1 - 0.023 14.8 0.2 0.13 12.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EMT51083.1 - 0.058 13.8 0.0 0.21 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMT51083.1 - 0.062 13.5 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMT51083.1 - 0.087 12.7 0.4 1.5 8.7 0.1 2.5 3 0 0 3 3 3 0 NACHT domain Orf78 PF06024.12 EMT51083.1 - 0.099 13.0 0.0 0.099 13.0 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) TsaE PF02367.17 EMT51083.1 - 0.099 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EMT51083.1 - 0.11 12.0 0.2 0.4 10.2 0.2 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EMT51083.1 - 0.13 12.3 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain YMF19 PF02326.15 EMT51083.1 - 0.29 12.0 1.0 0.67 10.8 0.0 2.1 2 0 0 2 2 1 0 Plant ATP synthase F0 Pox_EPC_I2-L1 PF12575.8 EMT51083.1 - 2.7 8.3 4.2 0.68 10.2 0.3 2.0 2 0 0 2 2 1 0 Poxvirus entry protein complex L1 and I2 SBP_bac_5 PF00496.22 EMT51084.1 - 5.9e-83 278.9 3.5 5.9e-83 278.9 3.5 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle BES1_N PF05687.13 EMT51084.1 - 0.11 12.9 0.5 0.57 10.6 0.0 2.1 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal BPD_transp_1 PF00528.22 EMT51085.1 - 6e-39 133.7 17.9 1.7e-38 132.2 15.9 2.0 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EMT51086.1 - 3.9e-31 108.2 5.8 3.9e-31 108.2 5.8 2.3 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT51086.1 - 1.1e-14 54.2 0.2 1.1e-14 54.2 0.2 3.3 3 1 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C DUF4731 PF15875.5 EMT51086.1 - 9.1 6.6 9.3 1.7 8.9 2.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4731) ABC_tran PF00005.27 EMT51087.1 - 2.8e-27 95.9 0.0 3.8e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT51087.1 - 6.8e-17 61.8 0.1 1.2e-16 61.0 0.1 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT51087.1 - 2.5e-05 24.2 1.3 6.7e-05 22.8 0.2 2.1 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51087.1 - 0.00023 20.6 0.0 0.00056 19.4 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT51087.1 - 0.0029 17.9 0.9 0.049 13.9 0.9 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT51087.1 - 0.0043 17.5 0.0 0.0065 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EMT51087.1 - 0.0066 16.0 0.0 0.28 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EMT51087.1 - 0.017 14.8 0.0 0.019 14.6 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 EMT51087.1 - 0.024 14.3 0.3 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase PF06745.13 EMT51087.1 - 0.037 13.4 0.3 0.41 9.9 0.0 2.0 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 EMT51087.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 EMT51087.1 - 0.06 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EMT51087.1 - 0.067 12.6 0.0 6.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 EMT51087.1 - 0.072 12.5 0.4 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 EMT51087.1 - 0.09 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 EMT51087.1 - 0.15 12.0 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AIG1 PF04548.16 EMT51087.1 - 0.2 11.0 0.1 0.43 9.9 0.1 1.5 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.27 EMT51088.1 - 2.8e-29 102.4 0.0 3.8e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT51088.1 - 1.7e-19 70.1 0.3 2.8e-19 69.4 0.3 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT51088.1 - 2.5e-05 24.3 0.8 0.026 14.3 0.1 2.3 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMT51088.1 - 0.007 16.6 0.2 0.015 15.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT51088.1 - 0.023 14.4 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT51088.1 - 0.03 14.7 0.1 0.046 14.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AIG1 PF04548.16 EMT51088.1 - 0.091 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 AIG1 family SMC_N PF02463.19 EMT51088.1 - 0.11 11.9 0.0 0.56 9.6 0.0 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EMT51088.1 - 0.2 11.7 0.3 0.38 10.8 0.3 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain G-alpha PF00503.20 EMT51088.1 - 0.26 10.4 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_13 PF13166.6 EMT51088.1 - 0.32 9.6 0.7 1.5 7.4 0.3 1.8 2 0 0 2 2 2 0 AAA domain Hydrolase_3 PF08282.12 EMT51089.1 - 3.2e-50 171.3 0.0 1.1e-49 169.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EMT51089.1 - 7.7e-17 61.6 0.0 1.1e-11 44.8 0.0 2.4 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EMT51089.1 - 6.1e-10 39.7 0.0 0.00056 20.3 0.0 3.1 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMT51089.1 - 1.2e-06 28.8 0.0 0.077 13.1 0.0 3.1 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 EMT51089.1 - 2.2e-05 23.7 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase HAD PF12710.7 EMT51089.1 - 0.00046 20.6 0.1 0.85 10.0 0.0 3.1 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EMT51089.1 - 0.00086 19.4 0.0 0.019 15.1 0.0 2.6 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase NadA PF02445.16 EMT51090.1 - 1.9e-121 404.8 1.4 2.2e-121 404.6 1.4 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein HIN PF02760.15 EMT51090.1 - 0.034 13.9 0.1 7.3 6.3 0.0 2.8 3 0 0 3 3 3 0 HIN-200/IF120x domain FTSW_RODA_SPOVE PF01098.19 EMT51091.1 - 1.1e-42 146.4 27.2 1.3e-42 146.1 27.2 1.0 1 0 0 1 1 1 1 Cell cycle protein PadR PF03551.14 EMT51092.1 - 2.3e-26 91.6 2.3 2.9e-26 91.2 2.3 1.1 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family RTP PF02334.16 EMT51092.1 - 0.0041 17.7 0.2 0.0052 17.4 0.2 1.1 1 0 0 1 1 1 1 Replication terminator protein HTH_34 PF13601.6 EMT51092.1 - 0.0073 16.5 0.1 0.012 15.8 0.1 1.4 1 1 0 1 1 1 1 Winged helix DNA-binding domain DUF2250 PF10007.9 EMT51092.1 - 0.024 14.7 2.1 1.2 9.3 2.1 2.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Acyl_transf_3 PF01757.22 EMT51093.1 - 3e-23 82.4 24.8 3e-23 82.4 24.8 1.8 2 0 0 2 2 2 1 Acyltransferase family VirB8 PF04335.13 EMT51093.1 - 0.047 13.5 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 VirB8 protein PCYCGC PF13798.6 EMT51094.1 - 4e-70 234.6 0.9 4.7e-70 234.4 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function with PCYCGC motif LPAM_1 PF08139.12 EMT51094.1 - 0.14 12.7 0.4 0.32 11.6 0.4 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site ZnuA PF01297.17 EMT51095.1 - 1.9e-80 270.0 5.9 2.3e-80 269.7 5.9 1.1 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic DUF1640 PF07798.11 EMT51095.1 - 0.067 13.2 1.7 0.15 12.1 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Zip PF02535.22 EMT51095.1 - 0.63 9.2 6.0 0.75 9.0 6.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter WG_beta_rep PF14903.6 EMT51096.1 - 1.9e-86 283.9 2.4 6.9e-14 51.8 0.0 9.1 6 2 3 9 9 9 9 WG containing repeat DsbC_N PF10411.9 EMT51096.1 - 0.032 13.7 0.1 7.5 6.1 0.0 3.4 3 0 0 3 3 3 0 Disulfide bond isomerase protein N-terminus MFS_1 PF07690.16 EMT51097.1 - 6e-39 133.9 47.8 6e-39 133.9 47.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT51097.1 - 3.5e-06 26.1 37.8 9.2e-06 24.8 17.0 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.7 EMT51097.1 - 0.0024 16.8 13.3 0.0024 16.8 13.3 2.1 1 1 1 2 2 2 2 MFS_1 like family HTH_20 PF12840.7 EMT51098.1 - 6.1e-13 48.6 0.0 8.2e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EMT51098.1 - 5.1e-11 42.3 0.1 3.5e-09 36.4 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 EMT51098.1 - 0.00015 21.6 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EMT51098.1 - 0.00062 19.3 0.2 0.0016 18.0 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 EMT51098.1 - 0.00098 19.3 0.1 0.0015 18.7 0.1 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_23 PF13384.6 EMT51098.1 - 0.0015 18.2 0.1 0.0045 16.7 0.1 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 EMT51098.1 - 0.0021 18.0 0.2 0.0026 17.7 0.2 1.4 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 EMT51098.1 - 0.0022 17.7 0.0 0.0036 17.1 0.0 1.4 1 1 0 1 1 1 1 IclR helix-turn-helix domain HTH_40 PF14493.6 EMT51098.1 - 0.0028 18.1 0.2 0.0058 17.1 0.1 1.5 1 1 1 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 EMT51098.1 - 0.003 17.4 0.1 0.005 16.7 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB FUR PF01475.19 EMT51098.1 - 0.0097 16.0 0.2 0.021 15.0 0.2 1.5 1 1 0 1 1 1 1 Ferric uptake regulator family Mnd1 PF03962.15 EMT51098.1 - 0.011 16.0 0.0 0.034 14.4 0.0 1.9 1 1 0 1 1 1 0 Mnd1 HTH domain HTH_11 PF08279.12 EMT51098.1 - 0.012 15.6 0.2 0.33 10.9 0.1 2.1 2 0 0 2 2 2 0 HTH domain Rrf2 PF02082.20 EMT51098.1 - 0.021 15.1 0.1 0.035 14.5 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_27 PF13463.6 EMT51098.1 - 0.03 14.8 0.0 0.045 14.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF4423 PF14394.6 EMT51098.1 - 0.032 13.9 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) MarR PF01047.22 EMT51098.1 - 0.042 13.8 0.4 0.082 12.8 0.1 1.6 2 0 0 2 2 2 0 MarR family Drf_FH3 PF06367.16 EMT51098.1 - 0.044 13.4 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Diaphanous FH3 Domain Penicillinase_R PF03965.16 EMT51098.1 - 0.046 14.1 0.2 0.067 13.6 0.2 1.3 1 0 0 1 1 1 0 Penicillinase repressor HTH_17 PF12728.7 EMT51098.1 - 0.091 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2250 PF10007.9 EMT51098.1 - 0.093 12.9 0.2 0.25 11.5 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) ABC_tran PF00005.27 EMT51099.1 - 5e-33 114.5 0.0 7.8e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT51099.1 - 4.4e-11 43.2 0.4 2.4e-05 24.3 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51099.1 - 5.2e-07 29.3 0.2 0.0052 16.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMT51099.1 - 5.9e-05 23.0 0.2 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EMT51099.1 - 8.3e-05 23.2 0.2 0.00017 22.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EMT51099.1 - 0.00021 21.4 0.1 0.009 16.2 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EMT51099.1 - 0.00057 19.6 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT51099.1 - 0.00081 19.7 0.2 0.0045 17.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EMT51099.1 - 0.0015 18.6 0.1 0.099 12.7 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EMT51099.1 - 0.002 17.9 0.2 0.0089 15.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMT51099.1 - 0.0059 16.4 0.1 0.014 15.2 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 EMT51099.1 - 0.0061 16.5 0.1 0.049 13.5 0.1 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EMT51099.1 - 0.01 15.0 0.5 0.057 12.6 0.5 2.4 1 1 0 1 1 1 0 NB-ARC domain ABC_ATPase PF09818.9 EMT51099.1 - 0.017 13.9 0.4 1.7 7.3 0.0 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_27 PF13514.6 EMT51099.1 - 0.019 14.6 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMT51099.1 - 0.035 13.7 0.1 3.9 7.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMT51099.1 - 0.04 14.3 0.2 0.072 13.5 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EMT51099.1 - 0.043 14.0 0.1 0.073 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMT51099.1 - 0.063 13.8 0.4 0.26 11.8 0.1 2.1 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EMT51099.1 - 0.066 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Adeno_IVa2 PF02456.15 EMT51099.1 - 0.081 11.7 0.0 0.47 9.2 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATP_bind_1 PF03029.17 EMT51099.1 - 0.082 12.7 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 EMT51099.1 - 0.084 12.8 1.0 0.53 10.2 1.0 2.1 1 1 0 1 1 1 0 NTPase NACHT PF05729.12 EMT51099.1 - 0.09 12.7 0.2 0.48 10.3 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 EMT51099.1 - 0.09 12.8 0.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EMT51099.1 - 0.11 12.6 0.2 0.22 11.6 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 EMT51099.1 - 0.14 12.6 0.3 0.96 9.9 0.3 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMT51099.1 - 0.14 12.2 0.2 0.34 10.9 0.2 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC-3 PF00950.17 EMT51100.1 - 4.4e-63 213.2 29.8 5.2e-63 212.9 29.8 1.1 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 EMT51100.1 - 5.7e-09 35.4 27.4 5.7e-09 35.4 27.4 1.5 1 1 0 1 1 1 1 FecCD transport family FUR PF01475.19 EMT51101.1 - 8.8e-27 93.6 0.0 1.1e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family RRM_5 PF13893.6 EMT51102.1 - 0.068 12.8 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_2 PF00890.24 EMT51103.1 - 2.6e-99 333.1 1.5 3.4e-99 332.7 1.5 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EMT51103.1 - 1.6e-18 66.9 5.4 1.8e-18 66.8 1.7 2.7 2 1 0 2 2 2 1 Fumarate reductase flavoprotein C-term DAO PF01266.24 EMT51103.1 - 7.1e-10 39.0 3.8 2.4e-09 37.3 3.8 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMT51103.1 - 3.8e-07 29.6 3.6 0.0011 18.3 2.5 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT51103.1 - 2.8e-06 26.3 0.1 0.00065 18.5 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 EMT51103.1 - 4e-05 22.9 0.4 0.048 12.7 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EMT51103.1 - 0.00029 20.3 3.3 0.0015 18.0 3.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMT51103.1 - 0.017 15.3 0.1 0.071 13.4 0.1 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EMT51103.1 - 0.11 11.8 0.8 0.37 10.0 0.3 1.9 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EMT51103.1 - 0.16 11.2 0.9 2.3 7.4 0.1 2.6 2 1 1 3 3 3 0 Thi4 family QRPTase_C PF01729.19 EMT51104.1 - 1.8e-66 223.1 3.6 2.4e-66 222.7 3.6 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EMT51104.1 - 2.4e-28 98.0 0.1 4.3e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.19 EMT51104.1 - 0.18 11.2 2.5 0.31 10.4 1.0 1.9 1 1 2 3 3 3 0 Ribulose-phosphate 3 epimerase family Pan_kinase PF03309.14 EMT51105.1 - 4e-73 245.7 0.0 4.7e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Type III pantothenate kinase MFS_1 PF07690.16 EMT51106.1 - 5.5e-59 199.9 59.3 5.8e-54 183.4 54.3 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT51106.1 - 2.2e-07 30.1 12.2 2.2e-07 30.1 12.2 2.8 1 1 0 2 2 2 1 Sugar (and other) transporter Myc_target_1 PF15179.6 EMT51106.1 - 0.38 10.6 0.1 0.38 10.6 0.1 2.7 3 0 0 3 3 3 0 Myc target protein 1 Claudin_2 PF13903.6 EMT51106.1 - 7.5 6.3 12.0 4.6 7.0 1.6 3.6 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction TetR_N PF00440.23 EMT51107.1 - 3.8e-10 39.4 0.0 8.3e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 EMT51107.1 - 2.4e-06 27.8 0.9 3.7e-06 27.2 0.9 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 EMT51107.1 - 2.4e-06 27.7 0.7 4.7e-06 26.8 0.7 1.4 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_13 PF16925.5 EMT51107.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.5 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 EMT51107.1 - 0.0071 16.4 0.4 0.013 15.5 0.3 1.5 1 1 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_24 PF17932.1 EMT51107.1 - 0.02 15.2 0.5 0.052 13.8 0.3 1.7 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Zn-ribbon_8 PF09723.10 EMT51108.1 - 7.9e-10 38.7 1.4 7.9e-10 38.7 1.4 2.0 3 0 0 3 3 3 1 Zinc ribbon domain CLIP1_ZNF PF16641.5 EMT51108.1 - 3.8 7.5 7.2 4.7 7.2 2.6 2.6 2 0 0 2 2 2 0 CLIP1 zinc knuckle FmdA_AmdA PF03069.15 EMT51109.1 - 3.6e-181 602.0 0.0 4.1e-181 601.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Lysis_col PF02402.16 EMT51110.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Lysis protein TraB PF01963.17 EMT51111.1 - 2.2e-65 221.2 0.5 3.2e-65 220.7 0.5 1.2 1 0 0 1 1 1 1 TraB family Cofac_haem_bdg PF04187.13 EMT51111.1 - 0.018 15.0 0.5 0.09 12.8 0.5 2.0 1 1 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN DUF4491 PF14898.6 EMT51112.1 - 1.2 9.6 4.8 1.1 9.8 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) TraB PF01963.17 EMT51114.1 - 2.6e-12 47.2 0.0 2.8e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 TraB family Cofac_haem_bdg PF04187.13 EMT51114.1 - 0.017 15.1 0.0 0.019 15.0 0.0 1.0 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN DoxX_2 PF13564.6 EMT51115.1 - 3.3e-09 36.8 0.3 4e-09 36.5 0.3 1.1 1 0 0 1 1 1 1 DoxX-like family DoxX PF07681.12 EMT51115.1 - 1.1e-07 32.4 1.2 1.3e-07 32.1 1.2 1.1 1 0 0 1 1 1 1 DoxX RcpC PF16976.5 EMT51116.1 - 5.3e-07 29.7 0.0 1.4e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Flp pilus assembly protein RcpC/CpaB Glyco_hydro_8 PF01270.17 EMT51116.1 - 0.23 10.2 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 AAA_31 PF13614.6 EMT51117.1 - 2.5e-12 47.1 0.0 1.5e-11 44.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 EMT51117.1 - 3.5e-10 40.0 0.0 7.2e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EMT51117.1 - 1.2e-08 34.7 0.1 0.001 18.6 0.0 2.2 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 EMT51117.1 - 8.1e-05 21.9 0.0 0.00093 18.5 0.0 2.2 1 1 0 1 1 1 1 Anion-transporting ATPase Response_reg PF00072.24 EMT51117.1 - 9.1e-05 22.6 0.0 0.0018 18.4 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain GFO_IDH_MocA PF01408.22 EMT51117.1 - 0.002 19.0 0.0 0.0048 17.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CBP_BcsQ PF06564.12 EMT51117.1 - 0.0088 15.5 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ NACHT PF05729.12 EMT51117.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Peptidase_M32 PF02074.15 EMT51117.1 - 0.16 10.7 0.1 0.22 10.2 0.1 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase T2SSE PF00437.20 EMT51118.1 - 5.9e-48 163.3 0.0 9.9e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 EMT51118.1 - 0.0023 17.2 0.0 0.0055 16.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.27 EMT51118.1 - 0.15 12.6 0.2 0.48 10.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter T2SSF PF00482.23 EMT51119.1 - 3.3e-09 36.8 3.6 7.3e-09 35.6 3.6 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F T2SSF PF00482.23 EMT51120.1 - 1.4e-09 38.0 1.6 1.4e-09 38.0 1.6 2.7 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein F MREG PF15812.5 EMT51120.1 - 0.016 15.5 0.1 0.031 14.6 0.1 1.4 1 0 0 1 1 1 0 Melanoregulin TIR PF01582.20 EMT51120.1 - 0.063 13.1 0.1 0.098 12.5 0.1 1.3 1 0 0 1 1 1 0 TIR domain TctB PF07331.11 EMT51120.1 - 0.4 10.9 6.9 0.12 12.7 2.0 2.2 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family BPD_transp_1 PF00528.22 EMT51120.1 - 4.6 6.9 9.8 8.1 6.1 2.6 2.5 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component Flp1_like PF16982.5 EMT51121.1 - 3.2e-06 26.4 4.3 5e-06 25.8 4.3 1.3 1 0 0 1 1 1 1 Putative Flagellin, Flp1-like, domain Flp_Fap PF04964.14 EMT51121.1 - 0.00019 21.2 0.5 0.00021 21.0 0.5 1.2 1 0 0 1 1 1 1 Flp/Fap pilin component N_methyl PF07963.12 EMT51121.1 - 0.002 17.6 2.1 0.0031 17.0 2.1 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Peptidase_A24 PF01478.18 EMT51122.1 - 9.2e-16 58.2 12.1 1.5e-15 57.5 12.1 1.3 1 0 0 1 1 1 1 Type IV leader peptidase family DUF3149 PF11346.8 EMT51122.1 - 0.066 12.8 0.0 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TadE PF07811.12 EMT51123.1 - 9.3e-06 25.8 0.3 1.5e-05 25.2 0.3 1.4 1 0 0 1 1 1 1 TadE-like protein ERG2_Sigma1R PF04622.12 EMT51125.1 - 0.015 14.7 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein DisA-linker PF10635.9 EMT51125.1 - 0.26 11.0 1.5 14 5.4 0.0 3.0 3 0 0 3 3 3 0 DisA bacterial checkpoint controller linker region DUF1722 PF08349.11 EMT51127.1 - 0.0016 18.7 0.7 0.0039 17.5 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) DUF682 PF05081.12 EMT51128.1 - 0.057 13.2 0.0 7.2 6.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF682) SAF PF08666.12 EMT51129.1 - 0.00069 20.2 0.1 0.0014 19.2 0.1 1.5 1 0 0 1 1 1 1 SAF domain AAA_31 PF13614.6 EMT51130.1 - 2.1e-06 27.8 0.0 2.5e-05 24.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain Beta_protein PF14350.6 EMT51130.1 - 0.0006 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Beta protein DUF1612 PF07756.12 EMT51130.1 - 0.02 15.2 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) Cas_VVA1548 PF09652.10 EMT51130.1 - 0.051 13.8 0.2 0.16 12.2 0.1 1.8 2 0 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) T2SSE PF00437.20 EMT51131.1 - 3e-25 88.8 0.0 4.8e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein TK PF00265.18 EMT51131.1 - 0.0021 17.9 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Thymidine kinase AAA_16 PF13191.6 EMT51131.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EMT51131.1 - 0.013 16.0 0.0 0.044 14.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 EMT51131.1 - 0.049 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ras PF00071.22 EMT51131.1 - 0.054 13.1 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 EMT51131.1 - 0.056 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EMT51131.1 - 0.075 13.1 0.0 0.32 11.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain HHH_2 PF12826.7 EMT51131.1 - 0.1 12.7 0.1 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF2730 PF10805.8 EMT51131.1 - 0.15 12.2 0.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) T2SSF PF00482.23 EMT51132.1 - 0.0012 18.8 0.4 0.0036 17.3 0.0 2.1 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein F DUF3169 PF11368.8 EMT51132.1 - 0.0026 17.3 5.9 0.36 10.3 0.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3169) DUF2207 PF09972.9 EMT51132.1 - 0.028 13.2 8.7 0.18 10.5 0.1 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 EMT51132.1 - 0.21 11.9 0.0 0.21 11.9 0.0 2.8 3 0 0 3 3 3 0 Orf78 (ac78) RPN6_N PF18055.1 EMT51133.1 - 0.032 14.6 0.1 0.088 13.2 0.0 1.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF3172 PF11371.8 EMT51134.1 - 0.05 13.3 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) 4HB_MCP_1 PF12729.7 EMT51135.1 - 0.012 15.2 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction ELO PF01151.18 EMT51135.1 - 0.1 12.1 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 GNS1/SUR4 family PhrC_PhrF PF11131.8 EMT51135.1 - 0.95 9.1 2.7 1.5 8.5 2.7 1.3 1 0 0 1 1 1 0 Rap-phr extracellular signalling RIIa PF02197.17 EMT51136.1 - 0.0048 16.5 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Form-deh_trans PF09163.11 EMT51136.1 - 0.087 12.6 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Xan_ur_permease PF00860.20 EMT51139.1 - 2e-57 194.6 43.3 2.8e-57 194.2 43.3 1.2 1 0 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EMT51139.1 - 0.54 10.7 38.1 0.032 14.6 2.9 5.0 3 2 2 5 5 5 0 Molybdate transporter of MFS superfamily LysR_substrate PF03466.20 EMT51140.1 - 7.6e-35 120.2 0.0 1e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT51140.1 - 2e-25 88.5 0.8 4.4e-25 87.4 0.4 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EMT51140.1 - 0.0023 17.7 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_5 PF01022.20 EMT51140.1 - 0.089 12.7 0.2 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Sigma70_r4 PF04545.16 EMT51141.1 - 6.8e-19 67.1 7.5 3.2e-17 61.8 0.9 3.2 3 1 0 3 3 3 2 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT51141.1 - 1.6e-14 53.4 0.2 1.6e-14 53.4 0.2 2.6 3 0 0 3 3 3 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 EMT51141.1 - 3.6e-05 23.8 3.3 0.00019 21.5 0.9 2.6 2 1 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 EMT51141.1 - 0.018 14.7 2.6 0.13 12.0 0.2 2.9 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_25 PF13413.6 EMT51141.1 - 0.03 14.2 0.5 8.9 6.3 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain DUF928 PF06051.12 EMT51141.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) HSP33 PF01430.19 EMT51142.1 - 2.1e-86 289.7 0.0 2.3e-86 289.5 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein Elf1 PF05129.13 EMT51142.1 - 0.088 12.9 0.3 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Rotamase_2 PF13145.6 EMT51143.1 - 1.6e-19 70.9 0.6 3e-19 70.0 0.1 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain SurA_N_3 PF13624.6 EMT51143.1 - 1.4e-13 51.0 9.5 2.3e-09 37.3 1.2 3.8 2 1 2 4 4 4 3 SurA N-terminal domain Rotamase_3 PF13616.6 EMT51143.1 - 2e-09 38.0 0.0 9.7e-09 35.8 0.0 2.1 2 1 1 3 3 3 1 PPIC-type PPIASE domain SurA_N PF09312.11 EMT51143.1 - 7.6e-09 35.7 5.6 7.3e-06 26.1 0.6 3.1 2 2 1 3 3 3 2 SurA N-terminal domain Rotamase PF00639.21 EMT51143.1 - 1e-08 36.0 0.0 6e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 PPIC-type PPIASE domain SurA_N_2 PF13623.6 EMT51143.1 - 1.5e-07 31.4 7.8 0.0093 15.8 0.6 3.5 2 1 2 4 4 4 3 SurA N-terminal domain Trigger_C PF05698.14 EMT51143.1 - 0.0018 18.3 5.4 0.077 13.0 0.2 3.4 2 1 1 3 3 3 2 Bacterial trigger factor protein (TF) C-terminus Tweety PF04906.13 EMT51143.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Tweety PALP PF00291.25 EMT51144.1 - 3.7e-71 239.9 0.5 4.2e-71 239.8 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 EMT51144.1 - 0.0023 17.9 0.1 0.01 15.8 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase LAL_C2 PF18603.1 EMT51144.1 - 0.076 13.2 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 Chorismate_bind PF00425.18 EMT51145.1 - 3.8e-101 338.0 1.1 5.7e-101 337.4 0.1 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EMT51145.1 - 1.6e-30 106.2 0.0 1.2e-29 103.3 0.0 2.3 2 1 1 3 3 3 1 Anthranilate synthase component I, N terminal region GATase PF00117.28 EMT51146.1 - 2.8e-56 190.3 0.0 3.1e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EMT51146.1 - 6.8e-11 42.3 0.2 1.8e-10 40.9 0.2 1.6 1 1 0 1 1 1 1 Peptidase C26 DUF839 PF05787.13 EMT51147.1 - 7.9e-135 451.0 0.2 2.3e-134 449.4 0.2 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF839) TAT_signal PF10518.9 EMT51147.1 - 0.0011 18.7 0.5 0.0029 17.4 0.5 1.8 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence CytB6-F_Fe-S PF08802.10 EMT51147.1 - 0.067 13.2 0.5 0.2 11.7 0.5 1.8 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit MttA_Hcf106 PF02416.16 EMT51148.1 - 3.2e-21 74.4 0.2 4.1e-21 74.1 0.2 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family DUF4834 PF16118.5 EMT51148.1 - 0.019 16.0 0.0 0.02 15.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TatC PF00902.18 EMT51149.1 - 4e-53 180.3 17.8 4.6e-53 180.1 17.8 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) Aminotran_4 PF01063.19 EMT51150.1 - 4.4e-52 177.1 0.0 5.2e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Pterin_bind PF00809.22 EMT51151.1 - 9e-86 287.5 0.6 1.2e-85 287.1 0.6 1.1 1 0 0 1 1 1 1 Pterin binding enzyme PEP_mutase PF13714.6 EMT51151.1 - 0.0004 19.9 2.7 1.3 8.4 0.9 3.4 1 1 2 3 3 3 2 Phosphoenolpyruvate phosphomutase CAT_RBD PF03123.15 EMT51151.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 CAT RNA binding domain FolB PF02152.18 EMT51152.1 - 1.1e-34 119.3 0.0 1.2e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase DinI PF06183.13 EMT51152.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 DinI-like family HPPK PF01288.20 EMT51153.1 - 1.8e-40 137.9 0.0 2.1e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) HTH_3 PF01381.22 EMT51154.1 - 5.5e-16 58.4 0.1 6.2e-16 58.2 0.1 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EMT51154.1 - 4.7e-14 52.5 0.1 5.3e-14 52.3 0.1 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EMT51154.1 - 5.4e-10 39.2 0.0 6.5e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EMT51154.1 - 9.8e-06 25.9 0.0 1.1e-05 25.8 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EMT51154.1 - 6.5e-05 22.7 0.0 0.00011 22.0 0.0 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 EMT51154.1 - 0.0015 18.0 0.1 0.0025 17.3 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_37 PF13744.6 EMT51154.1 - 0.0057 16.6 0.0 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain GntR PF00392.21 EMT51154.1 - 0.044 13.4 0.2 1.8 8.2 0.0 2.2 1 1 1 2 2 2 0 Bacterial regulatory proteins, gntR family YdaS_antitoxin PF15943.5 EMT51154.1 - 0.057 13.3 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Phage_CI_repr PF07022.13 EMT51154.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Dus PF01207.17 EMT51155.1 - 1.7e-106 355.9 0.2 2e-106 355.6 0.2 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EMT51155.1 - 3.1e-06 26.8 0.4 6.4e-06 25.8 0.1 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 EMT51155.1 - 0.00017 21.1 1.2 0.00024 20.6 1.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 EMT51155.1 - 0.00039 19.7 0.2 0.32 10.2 0.1 2.2 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase Oxidored_FMN PF00724.20 EMT51155.1 - 0.00082 18.7 0.3 0.061 12.6 0.1 2.5 2 1 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family SOR_SNZ PF01680.17 EMT51155.1 - 0.002 17.9 2.6 0.053 13.3 0.2 2.7 2 1 1 3 3 3 1 SOR/SNZ family PEP_mutase PF13714.6 EMT51155.1 - 0.0021 17.6 0.4 0.0058 16.1 0.3 1.7 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase MR_MLE_C PF13378.6 EMT51155.1 - 0.0027 17.3 0.3 0.0092 15.6 0.3 2.0 1 1 0 1 1 1 1 Enolase C-terminal domain-like FMN_dh PF01070.18 EMT51155.1 - 0.007 15.4 0.1 0.009 15.1 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 EMT51155.1 - 0.0087 15.3 0.1 0.027 13.6 0.1 1.7 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 EMT51155.1 - 0.018 14.4 0.1 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG GreA_GreB_N PF03449.15 EMT51156.1 - 3.1e-30 104.1 4.4 4.1e-30 103.7 4.4 1.2 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 EMT51156.1 - 2.9e-26 91.2 0.8 5.3e-26 90.3 0.8 1.4 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term Gal4_dimer PF03902.13 EMT51156.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain tRNA-synt_2 PF00152.20 EMT51157.1 - 4.1e-84 282.3 1.1 5.7e-84 281.9 1.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMT51157.1 - 1.2e-15 57.2 0.2 2.6e-15 56.2 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMT51157.1 - 5.9e-06 25.9 0.3 0.014 14.9 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF1129 PF06570.11 EMT51158.1 - 0.052 13.0 1.5 0.049 13.1 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) TPR_7 PF13176.6 EMT51159.1 - 3.2e-05 23.7 0.3 0.0064 16.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMT51159.1 - 0.0025 17.5 11.1 0.013 15.3 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMT51159.1 - 0.0054 17.0 0.7 0.16 12.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMT51159.1 - 0.019 15.1 0.1 0.019 15.1 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMT51159.1 - 0.021 15.5 0.7 2.4 9.0 0.0 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMT51159.1 - 0.023 15.5 0.3 1.2 10.2 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMT51159.1 - 0.15 12.4 4.7 1.8 9.0 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Peptidase_M10 PF00413.24 EMT51161.1 - 4.4e-05 23.4 0.1 5.8e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 EMT51161.1 - 0.0017 17.4 0.0 0.0056 15.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase M66 Peptidase_M43 PF05572.13 EMT51161.1 - 0.0022 17.9 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A SprT-like PF10263.9 EMT51161.1 - 0.0025 17.6 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_M54 PF07998.11 EMT51161.1 - 0.0066 16.4 0.0 0.0095 15.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M54 Astacin PF01400.24 EMT51161.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 EMT51161.1 - 0.025 14.2 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EMT51161.1 - 0.058 13.9 0.0 0.074 13.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 EMT51161.1 - 0.096 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M7 PF02031.16 EMT51161.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.6 1 1 1 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M57 PF12388.8 EMT51161.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF4953 PF16313.5 EMT51161.1 - 1.1 8.4 3.6 2.7 7.1 3.6 1.7 1 1 0 1 1 1 0 Met-zincin Ribonuc_red_sm PF00268.21 EMT51163.1 - 1.1e-13 51.3 1.3 1.2e-13 51.1 1.3 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain HTH_Tnp_1 PF01527.20 EMT51164.1 - 3.9e-14 52.7 2.2 4.6e-14 52.5 2.2 1.1 1 0 0 1 1 1 1 Transposase CENP-B_N PF04218.13 EMT51164.1 - 5.9e-06 25.8 1.3 7.9e-06 25.4 0.0 1.8 2 1 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 EMT51164.1 - 5.8e-05 22.8 0.1 0.00015 21.4 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EMT51164.1 - 8.7e-05 22.6 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 EMT51164.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase DUF1670 PF07900.11 EMT51164.1 - 0.016 14.5 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) HTH_Tnp_ISL3 PF13542.6 EMT51164.1 - 0.043 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF433 PF04255.14 EMT51164.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF433) rve_3 PF13683.6 EMT51165.1 - 0.034 13.9 0.0 0.037 13.8 0.0 1.0 1 0 0 1 1 1 0 Integrase core domain rve_2 PF13333.6 EMT51165.1 - 0.061 13.5 0.2 0.074 13.2 0.2 1.1 1 0 0 1 1 1 0 Integrase core domain CRISPR_Cas2 PF09827.9 EMT51166.1 - 7.5e-19 67.7 0.2 9.1e-19 67.4 0.2 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas2 Cas_Cas1 PF01867.16 EMT51167.1 - 3.1e-84 282.5 0.0 4.1e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas1 Cas_Cas4 PF01930.17 EMT51167.1 - 5.5e-27 94.9 0.0 3.9e-26 92.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 EMT51167.1 - 2.4e-13 50.6 0.2 1.3e-12 48.2 0.0 1.9 1 1 1 2 2 2 1 PD-(D/E)XK nuclease superfamily Cas_Cas5d PF09704.10 EMT51168.1 - 1.5e-07 31.5 0.0 7.7e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 CRISPR-associated protein (Cas_Cas5) Cas_Cmr3 PF09700.10 EMT51168.1 - 0.063 12.7 0.0 8.9 5.6 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr3) DevR PF01905.16 EMT51169.1 - 5.5e-09 35.5 0.2 1.2e-07 31.1 0.2 2.2 1 1 0 1 1 1 1 CRISPR-associated negative auto-regulator DevR/Csa2 Herpes_BLLF1 PF05109.13 EMT51169.1 - 0.18 9.7 0.0 0.23 9.4 0.0 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) ABC_tran_Xtn PF12848.7 EMT51170.1 - 0.012 15.6 1.2 0.15 12.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter HD_6 PF18019.1 EMT51171.1 - 4e-09 36.9 0.0 8.1e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 HD domain Helicase_C PF00271.31 EMT51171.1 - 5.8e-07 29.8 0.1 2.5e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HD PF01966.22 EMT51171.1 - 2e-05 24.8 0.1 5.7e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 HD domain DEAD PF00270.29 EMT51171.1 - 0.00052 19.8 0.0 0.0021 17.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Cas6 PF09559.10 EMT51172.1 - 5.2e-39 134.2 0.0 6.5e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Cas6 Crispr Pro_dh PF01619.18 EMT51173.1 - 2.1e-16 60.3 0.6 1e-15 58.1 0.6 2.0 1 1 0 1 1 1 1 Proline dehydrogenase Gemin7 PF11095.8 EMT51173.1 - 0.05 13.5 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) Thy1 PF02511.15 EMT51173.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Thymidylate synthase complementing protein Cdc6_C PF09079.11 EMT51173.1 - 0.11 12.5 0.0 1.8 8.6 0.0 2.8 3 0 0 3 3 3 0 CDC6, C terminal winged helix domain HEPN_AbiV PF18728.1 EMT51173.1 - 0.12 12.5 0.9 0.31 11.2 0.9 1.6 1 1 0 1 1 1 0 AbiV Aminotran_1_2 PF00155.21 EMT51174.1 - 9.7e-18 64.5 0.0 1.2e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EMT51174.1 - 6.1e-17 61.0 0.1 1.3e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_5 PF00266.19 EMT51174.1 - 0.02 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V HTH_24 PF13412.6 EMT51174.1 - 0.089 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Diacid_rec PF05651.13 EMT51175.1 - 5.2e-52 175.1 1.0 8.9e-52 174.3 1.0 1.4 1 0 0 1 1 1 1 Putative sugar diacid recognition HTH_30 PF13556.6 EMT51175.1 - 2.6e-20 72.0 0.0 6.3e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 EMT51175.1 - 1.8e-09 37.9 0.0 3.6e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 GGDEF-like domain GAF_2 PF13185.6 EMT51175.1 - 0.001 19.3 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 GAF domain HTH_8 PF02954.19 EMT51175.1 - 0.0019 17.9 0.0 0.0055 16.5 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family DUF2089 PF09862.9 EMT51175.1 - 0.044 13.8 1.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) SatD PF16264.5 EMT51175.1 - 0.57 9.7 4.0 15 5.1 0.3 2.7 3 0 0 3 3 3 0 SatD family (SatD) Gly_kinase PF02595.15 EMT51176.1 - 2.1e-151 504.1 3.7 2.4e-151 503.9 3.7 1.0 1 0 0 1 1 1 1 Glycerate kinase family PS_pyruv_trans PF04230.13 EMT51176.1 - 0.0059 16.6 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase KdgT PF03812.13 EMT51177.1 - 1.6e-88 297.0 32.9 4.2e-87 292.3 32.9 2.1 1 1 0 1 1 1 1 2-keto-3-deoxygluconate permease Diphtheria_T PF02764.14 EMT51177.1 - 0.14 12.2 1.4 0.23 11.5 1.4 1.3 1 0 0 1 1 1 0 Diphtheria toxin, T domain Lar_N PF09861.9 EMT51178.1 - 1.6e-71 239.7 0.0 2.3e-70 235.9 0.0 2.1 2 0 0 2 2 2 1 Lactate racemase N-terminal domain DUF362 PF04015.12 EMT51178.1 - 0.00024 21.4 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF362) GerA PF03323.13 EMT51179.1 - 2.3e-199 662.7 4.2 2.6e-199 662.5 4.2 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein Spore_GerAC PF05504.11 EMT51180.1 - 4.9e-42 144.0 1.6 9.8e-42 143.0 1.5 1.5 2 0 0 2 2 2 1 Spore germination B3/ GerAC like, C-terminal LPAM_1 PF08139.12 EMT51180.1 - 5.4 7.7 5.6 18 6.0 5.6 2.0 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site TctB PF07331.11 EMT51181.1 - 0.021 15.1 1.8 0.025 14.8 1.8 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Spore_permease PF03845.13 EMT51182.1 - 2.4e-61 207.3 30.1 3.3e-61 206.9 30.1 1.2 1 0 0 1 1 1 1 Spore germination protein Ribophorin_II PF05817.14 EMT51182.1 - 0.29 9.6 2.5 0.47 9.0 2.5 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II MFS_MOT1 PF16983.5 EMT51183.1 - 0.029 14.8 0.4 0.063 13.7 0.3 1.6 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily MASE4 PF17158.4 EMT51183.1 - 0.057 12.7 0.4 0.082 12.2 0.4 1.2 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain DUF4131 PF13567.6 EMT51183.1 - 9.3 5.9 6.0 2.4e+02 1.2 6.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) SieB PF14163.6 EMT51184.1 - 2.3 7.7 12.6 2.1 7.8 0.6 2.0 1 1 1 2 2 2 0 Super-infection exclusion protein B DUF3611 PF12263.8 EMT51184.1 - 3.5 7.5 10.4 4.6 7.1 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) MAPEG PF01124.18 EMT51184.1 - 4.3 7.3 10.4 1.6 8.7 2.0 2.1 1 1 1 2 2 2 0 MAPEG family DUF2070 PF09843.9 EMT51184.1 - 4.8 5.3 8.7 5.3 5.2 8.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2417 PF10329.9 EMT51184.1 - 9.1 5.6 12.5 19 4.6 12.7 1.4 1 1 0 1 1 1 0 Region of unknown function (DUF2417) DUF5360 PF17314.2 EMT51185.1 - 8.3e-50 168.1 10.1 9.3e-50 168.0 10.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5360) DUF485 PF04341.12 EMT51185.1 - 0.17 11.8 2.7 0.24 11.4 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF485 TetR_N PF00440.23 EMT51186.1 - 8e-12 44.8 0.3 2.2e-11 43.4 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 EMT51186.1 - 0.004 17.2 0.1 0.032 14.3 0.0 2.3 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_27 PF17935.1 EMT51186.1 - 0.014 15.4 0.1 0.095 12.8 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_4 PF08359.11 EMT51186.1 - 0.017 15.3 0.3 0.044 13.9 0.1 1.8 2 0 0 2 2 2 0 YsiA-like protein, C-terminal region HTH_Tnp_1_2 PF13022.6 EMT51186.1 - 0.018 15.2 0.1 0.21 11.7 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix of insertion element transposase HTH_3 PF01381.22 EMT51186.1 - 0.093 12.8 0.2 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix GntR PF00392.21 EMT51187.1 - 4.2e-16 58.3 0.0 1.1e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_1_2 PF00155.21 EMT51187.1 - 2e-14 53.6 0.0 3.3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EMT51187.1 - 0.001 18.0 0.0 0.25 10.1 0.0 2.6 3 0 0 3 3 3 2 Alanine-glyoxylate amino-transferase HTH_50 PF18024.1 EMT51187.1 - 0.0015 18.1 0.0 0.0041 16.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 EMT51187.1 - 0.0029 17.1 0.1 0.012 15.1 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Acetyltransf_3 PF13302.7 EMT51188.1 - 1.4e-20 74.4 0.0 1.8e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT51188.1 - 1.8e-09 37.8 0.0 2.6e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EMT51188.1 - 8.7e-09 35.7 0.0 9.6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT51188.1 - 8.3e-07 29.4 0.0 1.4e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMT51188.1 - 0.00033 20.4 0.0 0.00078 19.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT51188.1 - 0.00049 20.0 0.1 0.00075 19.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT51188.1 - 0.13 12.3 0.1 0.36 10.8 0.1 1.8 1 1 0 1 1 1 0 FR47-like protein Multi_Drug_Res PF00893.19 EMT51189.1 - 3.7e-23 82.0 3.7 4.5e-23 81.7 3.7 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein DUF308 PF03729.13 EMT51189.1 - 0.024 15.0 8.2 0.46 10.8 1.0 2.1 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF3796 PF12676.7 EMT51189.1 - 0.052 14.0 1.1 0.22 12.0 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3796) DUF2530 PF10745.9 EMT51189.1 - 0.45 10.8 3.4 0.17 12.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF4131 PF13567.6 EMT51189.1 - 4 7.1 5.8 3.9 7.1 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Multi_Drug_Res PF00893.19 EMT51190.1 - 8.2e-16 58.5 8.9 8.2e-16 58.5 8.9 1.9 2 0 0 2 2 2 1 Small Multidrug Resistance protein MerR_1 PF13411.6 EMT51191.1 - 1.5e-21 76.2 0.4 1.5e-21 76.2 0.4 2.0 3 0 0 3 3 3 1 MerR HTH family regulatory protein MerR PF00376.23 EMT51191.1 - 5.5e-13 48.5 1.9 1.2e-12 47.4 1.9 1.6 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 EMT51191.1 - 2.6e-07 31.0 4.9 7.7e-07 29.6 3.0 2.3 2 0 0 2 2 2 1 MerR, DNA binding TipAS PF07739.13 EMT51191.1 - 0.0047 17.4 0.0 0.017 15.7 0.0 1.9 2 0 0 2 2 2 1 TipAS antibiotic-recognition domain ARD PF03079.14 EMT51191.1 - 0.011 15.9 0.1 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 ARD/ARD' family DUF1836 PF08876.11 EMT51191.1 - 0.16 12.0 0.1 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) AHSA1 PF08327.11 EMT51192.1 - 1.4e-13 51.2 0.0 1.5e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein TetR_N PF00440.23 EMT51193.1 - 4.6e-14 51.9 0.3 7.9e-14 51.2 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 EMT51193.1 - 9.2e-06 25.7 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain HTH_Tnp_1_2 PF13022.6 EMT51193.1 - 0.0031 17.7 0.1 0.15 12.2 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 EMT51193.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain TetR_C_33 PF13305.6 EMT51193.1 - 0.11 13.2 0.0 1 10.1 0.0 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_27 PF13463.6 EMT51194.1 - 0.0014 19.1 0.4 0.0037 17.7 0.2 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain DUF1803 PF08820.10 EMT51194.1 - 0.013 15.5 0.1 0.027 14.5 0.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1803) MarR PF01047.22 EMT51194.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 MarR family Acetyltransf_1 PF00583.25 EMT51195.1 - 2e-15 57.1 0.1 2.3e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT51195.1 - 1.7e-13 50.6 0.0 2.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT51195.1 - 3.1e-11 43.5 0.2 4.8e-11 42.9 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT51195.1 - 3.3e-08 33.4 0.0 4.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EMT51195.1 - 2e-05 24.8 0.1 3.1e-05 24.1 0.0 1.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT51195.1 - 0.00046 20.3 0.0 0.00062 19.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMT51195.1 - 0.03 15.0 0.0 0.033 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMT51195.1 - 0.059 13.0 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT51195.1 - 0.067 13.3 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase XhlA PF10779.9 EMT51196.1 - 1.3e-10 41.3 12.7 0.0056 16.9 0.2 4.7 2 2 2 5 5 5 3 Haemolysin XhlA BLOC1_2 PF10046.9 EMT51196.1 - 2.3e-07 31.0 3.1 0.059 13.7 0.0 3.7 1 1 1 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EMT51196.1 - 2.3e-07 31.2 2.1 0.055 13.9 0.0 3.9 1 1 2 4 4 4 2 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 EMT51196.1 - 2.4e-07 31.0 17.6 0.068 13.5 1.9 5.1 1 1 3 4 4 4 3 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin-5_N PF11416.8 EMT51196.1 - 2.7e-07 29.6 0.2 3.9 6.8 0.0 4.7 4 0 0 4 4 4 0 Syntaxin-5 N-terminal, Sly1p-binding domain DUF1664 PF07889.12 EMT51196.1 - 2.9e-07 30.6 9.9 4.8e-06 26.6 2.5 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EMT51196.1 - 4e-07 30.2 1.7 7.6e-05 22.8 0.1 2.4 1 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 EMT51196.1 - 1.3e-06 28.6 13.4 0.034 14.5 0.1 4.3 2 2 3 5 5 4 3 Flagella accessory protein C (FlaC) Spc7 PF08317.11 EMT51196.1 - 2.7e-06 26.5 10.8 0.00017 20.6 0.8 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein AAA_13 PF13166.6 EMT51196.1 - 7.1e-06 25.0 3.5 8e-06 24.8 3.5 1.0 1 0 0 1 1 1 1 AAA domain MscS_porin PF12795.7 EMT51196.1 - 7.9e-06 25.6 3.4 0.052 13.1 0.1 2.6 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 EMT51196.1 - 8.4e-06 25.9 4.4 3.1e-05 24.1 0.2 2.2 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein SlyX PF04102.12 EMT51196.1 - 1.1e-05 25.9 4.7 0.001 19.6 0.2 4.1 1 1 3 4 4 4 2 SlyX Fib_alpha PF08702.10 EMT51196.1 - 1.5e-05 25.2 10.1 8.7e-05 22.7 2.2 2.9 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 EMT51196.1 - 1.7e-05 25.0 2.2 0.23 11.8 0.2 3.7 2 1 1 3 3 3 1 ABC transporter C-terminal domain DUF5082 PF16888.5 EMT51196.1 - 2e-05 24.9 2.3 0.035 14.4 0.4 3.0 1 1 0 2 2 2 1 Domain of unknown function (DUF5082) Prefoldin_2 PF01920.20 EMT51196.1 - 2.5e-05 24.2 11.2 0.24 11.4 0.3 4.5 1 1 6 7 7 7 1 Prefoldin subunit EzrA PF06160.12 EMT51196.1 - 2.8e-05 22.5 6.7 4.1e-05 22.0 6.7 1.3 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA DUF3829 PF12889.7 EMT51196.1 - 3.3e-05 23.5 1.3 0.00075 19.1 1.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3829) DUF3584 PF12128.8 EMT51196.1 - 3.5e-05 21.6 7.0 4.3e-05 21.3 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF16 PF01519.16 EMT51196.1 - 4.9e-05 23.8 8.9 0.00041 20.8 0.9 3.2 1 1 2 3 3 3 1 Protein of unknown function DUF16 Tropomyosin PF00261.20 EMT51196.1 - 6.4e-05 22.4 13.2 0.0035 16.7 2.8 2.2 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 EMT51196.1 - 8.3e-05 22.8 10.4 0.026 14.7 10.4 2.8 1 1 0 1 1 1 1 Tropomyosin like RmuC PF02646.16 EMT51196.1 - 9.1e-05 21.7 6.0 0.04 13.1 1.2 3.0 1 1 2 3 3 3 2 RmuC family Nup54 PF13874.6 EMT51196.1 - 0.00016 21.8 7.5 0.00017 21.7 3.6 2.6 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 Sec34 PF04136.15 EMT51196.1 - 0.00017 21.5 6.8 0.0016 18.3 1.6 2.6 1 1 2 3 3 3 2 Sec34-like family COG2 PF06148.11 EMT51196.1 - 0.00018 21.6 12.5 0.046 13.8 0.5 2.9 1 1 2 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 Snapin_Pallidin PF14712.6 EMT51196.1 - 0.00019 21.8 12.7 0.097 13.1 0.3 3.5 1 1 1 3 3 3 1 Snapin/Pallidin FemAB PF02388.16 EMT51196.1 - 0.00022 20.3 4.2 0.0095 14.9 0.1 2.0 2 0 0 2 2 2 1 FemAB family PspA_IM30 PF04012.12 EMT51196.1 - 0.00027 20.6 5.6 0.071 12.7 2.8 3.5 1 1 1 2 2 2 2 PspA/IM30 family YvrJ PF12841.7 EMT51196.1 - 0.00028 20.4 6.3 0.41 10.2 0.1 5.5 3 2 4 7 7 6 1 YvrJ protein family THOC7 PF05615.13 EMT51196.1 - 0.00028 21.2 4.0 0.00028 21.2 4.0 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 FPP PF05911.11 EMT51196.1 - 0.00029 19.2 12.8 0.00083 17.7 1.7 2.0 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil Syntaxin-6_N PF09177.11 EMT51196.1 - 0.0004 20.9 8.5 1.1 9.8 8.5 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal COG5 PF10392.9 EMT51196.1 - 0.0004 20.5 3.9 2.4 8.3 0.0 3.5 1 1 2 3 3 3 0 Golgi transport complex subunit 5 H-kinase_dim PF02895.14 EMT51196.1 - 0.00041 20.7 10.3 0.25 11.8 0.7 3.6 2 1 1 4 4 3 1 Signal transducing histidine kinase, homodimeric domain TMPIT PF07851.13 EMT51196.1 - 0.00044 19.6 9.8 0.0011 18.3 2.4 2.0 1 1 1 2 2 2 1 TMPIT-like protein HSBP1 PF06825.12 EMT51196.1 - 0.00053 19.8 23.2 0.21 11.5 0.2 4.7 3 1 1 4 4 3 1 Heat shock factor binding protein 1 Sec3_C PF09763.9 EMT51196.1 - 0.0006 18.3 7.0 0.13 10.7 0.1 2.9 2 1 1 3 3 3 1 Exocyst complex component Sec3 Lebercilin PF15619.6 EMT51196.1 - 0.00071 19.3 13.6 0.0023 17.6 1.8 2.2 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease KASH_CCD PF14662.6 EMT51196.1 - 0.00076 19.4 1.7 0.00076 19.4 1.7 2.2 2 1 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Med2 PF11214.8 EMT51196.1 - 0.00079 19.5 5.6 0.24 11.6 0.6 2.9 1 1 1 2 2 2 1 Mediator complex subunit 2 CENP-F_leu_zip PF10473.9 EMT51196.1 - 0.00079 19.5 16.8 0.012 15.6 4.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 EMT51196.1 - 0.00082 19.0 7.6 0.0024 17.5 7.6 1.7 1 1 0 1 1 1 1 Exonuclease VII, large subunit DUF4407 PF14362.6 EMT51196.1 - 0.0011 18.4 1.7 0.0042 16.5 1.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Laminin_II PF06009.12 EMT51196.1 - 0.0012 18.9 8.9 0.063 13.3 0.4 2.7 1 1 2 3 3 3 1 Laminin Domain II Occludin_ELL PF07303.13 EMT51196.1 - 0.0014 19.3 6.4 0.01 16.6 1.3 2.6 1 1 2 3 3 3 1 Occludin homology domain CCDC-167 PF15188.6 EMT51196.1 - 0.0016 18.8 11.9 2.2 8.7 3.1 4.1 1 1 3 4 4 4 0 Coiled-coil domain-containing protein 167 CEP63 PF17045.5 EMT51196.1 - 0.0016 18.4 8.1 0.021 14.7 3.0 2.0 1 1 0 1 1 1 1 Centrosomal protein of 63 kDa COG6 PF06419.11 EMT51196.1 - 0.0017 16.7 8.8 0.0048 15.2 2.5 2.1 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 YkyA PF10368.9 EMT51196.1 - 0.0017 18.1 6.7 0.0038 16.9 5.8 1.8 1 1 0 1 1 1 1 Putative cell-wall binding lipoprotein IFT20 PF14931.6 EMT51196.1 - 0.0017 18.5 10.6 0.031 14.4 0.8 3.0 1 1 2 3 3 3 1 Intraflagellar transport complex B, subunit 20 Matrilin_ccoil PF10393.9 EMT51196.1 - 0.0018 18.1 9.8 0.14 12.0 0.0 4.6 2 1 2 4 4 4 1 Trimeric coiled-coil oligomerisation domain of matrilin RRF_GI PF12614.8 EMT51196.1 - 0.0018 18.4 4.8 0.53 10.4 0.6 2.8 2 1 1 3 3 3 1 Ribosome recycling factor DUF4298 PF14131.6 EMT51196.1 - 0.0019 18.1 2.8 8.6 6.4 0.1 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) RPW8 PF05659.11 EMT51196.1 - 0.0019 17.9 10.2 0.038 13.7 3.0 3.5 1 1 2 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF724 PF05266.14 EMT51196.1 - 0.002 18.0 10.9 0.0026 17.6 1.9 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF724) DASH_Duo1 PF08651.10 EMT51196.1 - 0.0021 17.8 4.1 2.2 8.1 0.1 3.9 3 1 1 4 4 4 0 DASH complex subunit Duo1 ADIP PF11559.8 EMT51196.1 - 0.0022 18.1 10.1 0.13 12.4 0.9 3.4 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding FliD_N PF02465.18 EMT51196.1 - 0.0023 18.6 5.2 0.88 10.3 5.2 2.9 1 1 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus Gp58 PF07902.11 EMT51196.1 - 0.0023 16.3 4.2 0.0032 15.8 4.2 1.2 1 0 0 1 1 1 1 gp58-like protein DUF2730 PF10805.8 EMT51196.1 - 0.0025 17.9 9.4 0.035 14.2 1.2 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF2730) HrpB7 PF09486.10 EMT51196.1 - 0.0025 18.2 8.2 0.065 13.6 0.8 3.3 1 1 2 3 3 3 1 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.8 EMT51196.1 - 0.0027 17.7 7.5 7.9 6.6 0.7 4.0 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Spectrin PF00435.21 EMT51196.1 - 0.0031 18.0 5.9 0.11 13.0 1.3 2.5 1 1 1 2 2 2 2 Spectrin repeat SOAR PF16533.5 EMT51196.1 - 0.0032 17.4 10.8 0.1 12.6 1.1 3.1 1 1 0 2 2 2 1 STIM1 Orai1-activating region DUF2203 PF09969.9 EMT51196.1 - 0.0037 18.0 7.5 0.0084 16.8 0.6 2.2 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2203) HMMR_N PF15905.5 EMT51196.1 - 0.0038 16.8 7.7 0.0071 15.9 5.6 1.9 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal DUF3450 PF11932.8 EMT51196.1 - 0.004 16.5 14.0 0.026 13.8 5.1 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF3450) PEARLI-4 PF05278.12 EMT51196.1 - 0.0046 16.6 3.7 0.0046 16.6 3.7 2.7 1 1 2 3 3 3 2 Arabidopsis phospholipase-like protein (PEARLI 4) DUF3552 PF12072.8 EMT51196.1 - 0.0046 16.4 11.6 0.13 11.6 0.3 2.9 1 1 2 3 3 3 2 Domain of unknown function (DUF3552) IFT57 PF10498.9 EMT51196.1 - 0.0049 15.9 3.2 0.0049 15.9 3.2 1.9 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 CALCOCO1 PF07888.11 EMT51196.1 - 0.005 15.8 14.2 0.0071 15.3 14.2 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Nsp1_C PF05064.13 EMT51196.1 - 0.0052 16.6 7.8 2.4 8.0 0.2 3.7 1 1 3 4 4 3 0 Nsp1-like C-terminal region FapA PF03961.13 EMT51196.1 - 0.0055 15.4 6.7 0.025 13.2 0.2 2.0 1 1 1 2 2 2 1 Flagellar Assembly Protein A V-SNARE PF05008.15 EMT51196.1 - 0.0069 16.7 12.7 0.88 10.0 2.8 3.5 2 1 3 5 5 4 1 Vesicle transport v-SNARE protein N-terminus Trimer_CC PF08954.11 EMT51196.1 - 0.0069 15.9 12.4 0.67 9.6 0.3 4.1 2 1 1 3 3 3 2 Trimerisation motif GAS PF13851.6 EMT51196.1 - 0.0074 15.7 10.3 0.058 12.7 8.6 2.0 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spc24 PF08286.11 EMT51196.1 - 0.0074 16.5 12.8 2.1 8.6 2.4 3.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 APG17 PF04108.12 EMT51196.1 - 0.0075 15.4 8.6 0.033 13.3 5.5 2.2 1 1 1 2 2 2 2 Autophagy protein Apg17 MafB PF06255.13 EMT51196.1 - 0.0076 15.7 0.4 0.51 9.7 0.2 2.1 1 1 1 2 2 2 1 Neisseria toxin MafB Syntaxin PF00804.25 EMT51196.1 - 0.0078 15.9 4.0 0.0078 15.9 4.0 2.1 1 1 1 2 2 2 1 Syntaxin Filament PF00038.21 EMT51196.1 - 0.008 15.8 3.1 0.008 15.8 3.1 2.0 1 1 1 2 2 2 1 Intermediate filament protein PI3K_P85_iSH2 PF16454.5 EMT51196.1 - 0.0094 15.6 6.2 0.024 14.2 6.2 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SKA2 PF16740.5 EMT51196.1 - 0.0096 15.7 11.2 0.079 12.7 3.1 3.3 1 1 2 3 3 3 1 Spindle and kinetochore-associated protein 2 FliJ PF02050.16 EMT51196.1 - 0.01 16.1 6.7 0.078 13.2 0.5 2.9 1 1 2 3 3 3 0 Flagellar FliJ protein HsbA PF12296.8 EMT51196.1 - 0.01 16.3 0.0 0.15 12.5 0.0 2.2 1 1 1 2 2 2 0 Hydrophobic surface binding protein A FH2 PF02181.23 EMT51196.1 - 0.01 15.0 11.3 0.088 11.9 1.5 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain ISG65-75 PF11727.8 EMT51196.1 - 0.011 15.0 2.9 0.46 9.7 0.5 2.0 2 0 0 2 2 2 0 Invariant surface glycoprotein WXG100 PF06013.12 EMT51196.1 - 0.011 16.0 6.2 1.3 9.3 0.8 3.7 1 1 3 4 4 4 0 Proteins of 100 residues with WXG DUF4618 PF15397.6 EMT51196.1 - 0.011 15.2 13.4 0.31 10.4 1.4 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) ERM PF00769.19 EMT51196.1 - 0.012 15.5 4.6 0.012 15.5 4.6 2.0 1 1 0 2 2 2 0 Ezrin/radixin/moesin family NiFeSe_Hases PF00374.19 EMT51196.1 - 0.013 14.4 0.3 0.015 14.2 0.3 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Atg14 PF10186.9 EMT51196.1 - 0.014 14.5 5.7 0.016 14.3 5.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 EMT51196.1 - 0.015 15.9 0.7 0.015 15.9 0.7 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 UPF0184 PF03670.13 EMT51196.1 - 0.016 15.6 6.7 1.5 9.3 0.3 3.6 1 1 3 4 4 3 0 Uncharacterised protein family (UPF0184) DUF812 PF05667.11 EMT51196.1 - 0.016 14.1 10.6 0.054 12.4 10.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Prefoldin PF02996.17 EMT51196.1 - 0.017 15.1 10.6 7.4 6.5 0.2 4.4 2 2 3 5 5 5 0 Prefoldin subunit CENP-K PF11802.8 EMT51196.1 - 0.017 14.7 2.3 0.017 14.7 2.3 2.0 1 1 1 2 2 2 0 Centromere-associated protein K DUF2968 PF11180.8 EMT51196.1 - 0.018 14.7 1.0 0.018 14.7 1.0 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) Jnk-SapK_ap_N PF09744.9 EMT51196.1 - 0.021 15.1 11.0 0.04 14.2 2.5 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 EMT51196.1 - 0.022 15.2 10.8 0.095 13.1 10.8 1.8 1 1 0 1 1 1 0 Fez1 CorA PF01544.18 EMT51196.1 - 0.022 14.1 10.6 0.3 10.3 2.7 3.0 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein EMP24_GP25L PF01105.24 EMT51196.1 - 0.022 14.7 16.0 0.6 10.0 8.6 3.1 1 1 2 3 3 2 0 emp24/gp25L/p24 family/GOLD GIT_CC PF16559.5 EMT51196.1 - 0.022 14.6 6.6 0.6 10.0 0.1 4.0 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Leu_zip PF15294.6 EMT51196.1 - 0.023 14.2 10.0 0.011 15.2 6.1 1.9 1 1 1 2 2 2 0 Leucine zipper BRE1 PF08647.11 EMT51196.1 - 0.023 14.7 8.8 1.3 9.2 0.1 3.2 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF148 PF02520.17 EMT51196.1 - 0.026 14.6 2.3 0.74 10.0 0.1 3.0 1 1 3 4 4 4 0 Domain of unknown function DUF148 DHR10 PF18595.1 EMT51196.1 - 0.027 14.5 14.4 2.7 8.1 6.4 3.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TACC_C PF05010.14 EMT51196.1 - 0.028 14.2 10.0 0.21 11.3 10.0 2.2 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1054 PF06335.12 EMT51196.1 - 0.028 14.3 2.6 1.5 8.7 0.0 2.9 1 1 2 3 3 2 0 Protein of unknown function (DUF1054) Sas10_Utp3 PF04000.15 EMT51196.1 - 0.029 15.0 3.0 1.7 9.4 0.6 3.3 2 2 0 2 2 2 0 Sas10/Utp3/C1D family TBCC_N PF16752.5 EMT51196.1 - 0.03 14.8 6.4 0.28 11.7 2.8 2.9 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DASH_Dam1 PF08653.10 EMT51196.1 - 0.031 14.1 5.9 11 5.9 0.2 3.8 2 1 2 4 4 4 0 DASH complex subunit Dam1 DUF4337 PF14235.6 EMT51196.1 - 0.033 14.3 0.6 0.44 10.6 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) T3SSipB PF16535.5 EMT51196.1 - 0.034 14.6 0.5 1.8 9.0 0.5 3.0 1 1 0 1 1 1 0 Type III cell invasion protein SipB TFR_dimer PF04253.15 EMT51196.1 - 0.036 14.2 3.9 5.1 7.2 0.3 2.8 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain DASH_Dad3 PF08656.10 EMT51196.1 - 0.037 14.1 5.1 37 4.5 5.1 3.2 1 1 0 1 1 1 0 DASH complex subunit Dad3 TraF_2 PF13729.6 EMT51196.1 - 0.037 13.4 1.0 1.9 7.8 0.2 2.4 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein MtrG PF04210.13 EMT51196.1 - 0.042 13.7 4.5 2.5 8.0 0.0 4.0 3 1 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4164 PF13747.6 EMT51196.1 - 0.043 14.1 12.4 0.046 14.0 2.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Bacillus_HBL PF05791.11 EMT51196.1 - 0.044 13.6 2.6 0.46 10.3 0.2 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Laminin_I PF06008.14 EMT51196.1 - 0.052 13.2 11.1 0.098 12.3 1.1 2.7 1 1 2 3 3 3 0 Laminin Domain I DUF4349 PF14257.6 EMT51196.1 - 0.068 12.6 9.6 0.56 9.6 4.0 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF4349) DUF3540 PF12059.8 EMT51196.1 - 0.072 12.9 5.7 0.59 9.9 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) DUF641 PF04859.12 EMT51196.1 - 0.087 13.2 10.7 0.064 13.6 1.8 3.2 1 1 2 3 3 2 0 Plant protein of unknown function (DUF641) DUF4795 PF16043.5 EMT51196.1 - 0.097 12.3 14.9 0.44 10.1 6.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Vps51 PF08700.11 EMT51196.1 - 0.1 12.7 10.8 11 6.2 1.9 4.2 2 1 2 4 4 3 0 Vps51/Vps67 DUF4763 PF15960.5 EMT51196.1 - 0.1 11.9 6.2 0.11 11.8 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Prominin PF05478.11 EMT51196.1 - 0.11 10.5 5.1 0.19 9.6 5.1 1.5 1 1 0 1 1 1 0 Prominin CENP-H PF05837.12 EMT51196.1 - 0.12 12.8 8.7 2.4 8.6 1.8 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) CC2-LZ PF16516.5 EMT51196.1 - 0.12 12.7 9.3 3 8.2 0.3 3.7 1 1 3 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF5446 PF17522.2 EMT51196.1 - 0.13 12.5 9.4 2.9 8.1 0.3 3.9 1 1 3 4 4 4 0 Family of unknown function (DUF5446) LXG PF04740.12 EMT51196.1 - 0.13 11.9 7.8 1.5 8.5 1.0 3.0 1 1 0 1 1 1 0 LXG domain of WXG superfamily MCPsignal PF00015.21 EMT51196.1 - 0.14 12.0 5.7 0.14 12.0 1.5 2.2 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4140 PF13600.6 EMT51196.1 - 0.14 12.6 7.5 18 5.8 0.2 3.9 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 EMT51196.1 - 0.16 12.1 9.1 0.031 14.4 1.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rx_N PF18052.1 EMT51196.1 - 0.17 12.2 5.4 2 8.7 1.0 2.8 1 1 1 2 2 2 0 Rx N-terminal domain PTRF_SDPR PF15237.6 EMT51196.1 - 0.17 11.5 12.8 0.21 11.2 3.4 2.8 1 1 2 3 3 3 0 PTRF/SDPR family DUF4200 PF13863.6 EMT51196.1 - 0.2 12.1 10.0 0.093 13.1 4.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Not3 PF04065.15 EMT51196.1 - 0.25 10.8 9.6 0.38 10.2 1.0 2.1 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Tweety PF04906.13 EMT51196.1 - 0.25 10.0 5.7 0.6 8.7 0.5 2.5 1 1 2 3 3 3 0 Tweety Cluap1 PF10234.9 EMT51196.1 - 0.26 10.7 8.7 0.51 9.7 0.8 2.6 1 1 2 3 3 3 0 Clusterin-associated protein-1 DUF745 PF05335.13 EMT51196.1 - 0.26 11.0 4.5 0.74 9.5 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) V_ATPase_I PF01496.19 EMT51196.1 - 0.27 9.1 12.6 0.072 11.0 5.8 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF2802 PF10975.8 EMT51196.1 - 0.28 11.3 10.0 14 5.9 0.2 4.3 3 1 0 3 3 2 0 Protein of unknown function (DUF2802) DUF4988 PF16378.5 EMT51196.1 - 0.29 10.8 2.1 6.9 6.3 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function APG6_N PF17675.1 EMT51196.1 - 0.31 11.6 10.6 0.43 11.1 1.2 2.2 1 1 0 2 2 2 0 Apg6 coiled-coil region LTXXQ PF07813.12 EMT51196.1 - 0.32 11.7 10.8 0.34 11.7 1.3 3.0 1 1 2 3 3 2 0 LTXXQ motif family protein Phage_tail_NK PF16532.5 EMT51196.1 - 0.32 10.6 2.0 0.93 9.1 0.4 2.5 1 1 3 4 4 3 0 Sf6-type phage tail needle knob or tip of some Caudovirales TolA_bind_tri PF16331.5 EMT51196.1 - 0.32 11.1 10.6 0.047 13.8 2.8 2.9 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF4446 PF14584.6 EMT51196.1 - 0.32 11.0 8.1 3 7.8 2.8 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF4446) DUF948 PF06103.11 EMT51196.1 - 0.33 11.2 7.9 4.2 7.7 0.7 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Tup_N PF08581.10 EMT51196.1 - 0.34 11.2 10.7 0.43 10.9 4.4 3.0 1 1 3 4 4 4 0 Tup N-terminal Swi5 PF07061.11 EMT51196.1 - 0.39 10.8 4.3 1.3e+02 2.7 4.3 3.7 1 1 0 1 1 1 0 Swi5 TRAF_BIRC3_bd PF16673.5 EMT51196.1 - 0.43 10.4 7.9 4.4 7.2 0.7 3.5 2 1 2 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain Fzo_mitofusin PF04799.13 EMT51196.1 - 0.46 10.0 11.6 0.24 11.0 3.7 2.8 1 1 0 2 2 2 0 fzo-like conserved region KfrA_N PF11740.8 EMT51196.1 - 0.49 11.1 4.9 2.2 9.0 0.4 3.1 1 1 2 4 4 2 0 Plasmid replication region DNA-binding N-term REC1 PF18501.1 EMT51196.1 - 0.54 10.1 4.9 15 5.4 4.9 2.0 1 1 0 1 1 1 0 Alpha helical recognition lobe domain YabA PF06156.13 EMT51196.1 - 0.56 10.9 10.0 66 4.2 10.0 3.0 1 1 0 1 1 1 0 Initiation control protein YabA Lectin_N PF03954.14 EMT51196.1 - 0.59 9.9 5.4 2.5 7.9 0.6 2.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain FUSC PF04632.12 EMT51196.1 - 0.61 8.6 4.5 0.69 8.4 4.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family STAT_alpha PF01017.20 EMT51196.1 - 0.8 9.6 10.9 8 6.3 10.5 2.2 1 1 0 1 1 1 0 STAT protein, all-alpha domain Phage_GPO PF05929.11 EMT51196.1 - 0.81 9.3 9.1 0.23 11.0 3.1 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase KxDL PF10241.9 EMT51196.1 - 0.86 9.9 11.7 7 7.0 4.6 3.6 1 1 2 3 3 3 0 Uncharacterized conserved protein DLP_helical PF18709.1 EMT51196.1 - 0.86 8.7 8.6 2.4 7.3 4.6 2.7 1 1 1 2 2 2 0 Dynamin-like helical domain Taxilin PF09728.9 EMT51196.1 - 0.92 8.6 16.3 0.064 12.4 7.1 2.1 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DegS PF05384.11 EMT51196.1 - 0.93 9.0 13.6 0.4 10.1 2.3 3.4 1 1 3 4 4 4 0 Sensor protein DegS PRKG1_interact PF15898.5 EMT51196.1 - 1.1 10.2 16.2 1.1 10.2 5.1 2.4 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DMPK_coil PF08826.10 EMT51196.1 - 1.2 9.3 12.6 6 7.1 0.5 3.9 2 2 2 4 4 3 0 DMPK coiled coil domain like MutS_IV PF05190.18 EMT51196.1 - 1.2 9.5 7.2 10 6.6 0.2 3.8 2 2 2 4 4 3 0 MutS family domain IV ATG16 PF08614.11 EMT51196.1 - 1.5 9.0 13.4 0.25 11.6 4.6 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fmp27_WPPW PF10359.9 EMT51196.1 - 1.6 7.5 11.9 0.53 9.1 2.9 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain GTP-bdg_M PF16360.5 EMT51196.1 - 1.9 9.2 5.6 9.4 6.9 0.3 3.0 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region DUF773 PF05600.12 EMT51196.1 - 2.2 6.9 10.7 0.48 9.1 2.3 2.2 1 1 1 2 2 2 0 CDK5 regulatory subunit-associated protein 3 DUF3782 PF12644.7 EMT51196.1 - 2.5 8.3 10.5 9.6 6.4 1.3 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF3782) Cnn_1N PF07989.11 EMT51196.1 - 2.9 8.1 11.8 9 6.5 2.6 2.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 FAM76 PF16046.5 EMT51196.1 - 3.6 6.9 8.5 22 4.3 8.5 2.0 1 1 0 1 1 1 0 FAM76 protein HIP1_clath_bdg PF16515.5 EMT51196.1 - 5.2 7.7 15.2 2.9 8.6 2.2 2.9 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TEX13 PF15186.6 EMT51196.1 - 5.9 6.6 9.9 1.3 8.7 1.4 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family RNase_H_2 PF13482.6 EMT51197.1 - 2.1e-38 132.0 0.0 4.3e-38 130.9 0.0 1.5 2 0 0 2 2 2 1 RNase_H superfamily TPR_6 PF13174.6 EMT51197.1 - 5.8e-06 26.6 0.6 0.023 15.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMT51197.1 - 2.5e-05 24.5 1.4 0.00062 20.0 0.1 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat DNA_pol_B_exo1 PF03104.19 EMT51197.1 - 0.0016 17.6 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 EMT51197.1 - 0.0098 15.6 0.0 0.063 12.9 0.0 2.1 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB TPR_7 PF13176.6 EMT51197.1 - 0.025 14.6 1.3 4.5 7.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMT51197.1 - 0.061 13.5 2.9 5.7 7.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMT51197.1 - 0.088 13.1 0.6 2 8.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMT51197.1 - 0.51 11.3 5.0 0.28 12.1 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.29 EMT51198.1 - 2e-28 99.3 0.0 5.7e-28 97.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EMT51198.1 - 4.2e-22 78.7 0.1 9.8e-22 77.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EMT51198.1 - 1.1e-14 54.8 0.0 9.2e-13 48.5 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMT51198.1 - 1.4e-07 31.6 0.0 3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AP_endonuc_2 PF01261.24 EMT51199.1 - 1.1e-40 139.4 0.4 1.5e-40 138.9 0.4 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PRMT5_TIM PF17285.2 EMT51199.1 - 0.082 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 PRMT5 TIM barrel domain DUF570 PF04489.13 EMT51199.1 - 0.18 10.4 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF570) ABC_membrane PF00664.23 EMT51200.1 - 4.5e-60 203.6 10.3 5.9e-60 203.2 10.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMT51200.1 - 3.8e-32 111.7 0.0 7.9e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EMT51200.1 - 0.0002 21.8 0.1 0.0011 19.4 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EMT51200.1 - 0.00038 21.0 0.0 0.00072 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMT51200.1 - 0.00067 19.9 0.1 0.0049 17.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain ABC_membrane_3 PF13748.6 EMT51200.1 - 0.0011 18.3 0.5 0.0046 16.2 0.1 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA PF00004.29 EMT51200.1 - 0.0014 19.0 0.0 0.015 15.7 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 EMT51200.1 - 0.0035 17.2 0.4 3 7.6 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EMT51200.1 - 0.0038 17.2 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EMT51200.1 - 0.0069 15.8 0.7 1.5 8.2 0.1 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EMT51200.1 - 0.011 15.8 0.1 0.043 13.9 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EMT51200.1 - 0.016 14.9 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EMT51200.1 - 0.024 14.3 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EMT51200.1 - 0.031 13.3 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 EMT51200.1 - 0.032 13.5 0.1 0.092 12.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AdoHcyase PF05221.17 EMT51200.1 - 0.043 12.9 0.1 0.099 11.8 0.0 1.5 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase DUF87 PF01935.17 EMT51200.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TsaE PF02367.17 EMT51200.1 - 0.049 13.6 0.1 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EMT51200.1 - 0.049 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TrkA_N PF02254.18 EMT51200.1 - 0.055 13.7 0.1 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain cobW PF02492.19 EMT51200.1 - 0.065 12.8 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EMT51200.1 - 0.069 13.4 0.3 0.35 11.1 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 EMT51200.1 - 0.092 12.9 0.1 0.31 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EMT51200.1 - 0.093 12.5 0.1 0.67 9.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_membrane_2 PF06472.15 EMT51200.1 - 0.097 12.1 2.1 0.19 11.1 2.1 1.5 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 ABC_membrane PF00664.23 EMT51201.1 - 2.9e-49 168.2 16.4 4.1e-49 167.7 16.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMT51201.1 - 1.5e-27 96.8 0.0 3.1e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT51201.1 - 1.9e-06 27.5 2.3 0.00019 21.0 0.1 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EMT51201.1 - 0.0051 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.8 EMT51201.1 - 0.0078 13.8 0.1 0.012 13.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_30 PF13604.6 EMT51201.1 - 0.013 15.2 0.2 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EMT51201.1 - 0.028 14.2 1.6 0.065 13.0 0.7 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 EMT51201.1 - 0.028 14.5 0.3 0.071 13.2 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_19 PF13245.6 EMT51201.1 - 0.033 14.5 0.8 0.1 12.9 0.8 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EMT51201.1 - 0.043 14.3 1.0 0.087 13.3 1.0 1.4 1 0 0 1 1 1 0 AAA domain TrkA_N PF02254.18 EMT51201.1 - 0.048 13.9 0.1 0.27 11.5 0.0 2.4 1 1 1 2 2 2 0 TrkA-N domain NTPase_1 PF03266.15 EMT51201.1 - 0.082 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_21 PF13304.6 EMT51201.1 - 0.27 11.0 0.4 1 9.1 0.5 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TetR_N PF00440.23 EMT51202.1 - 7.7e-12 44.8 0.4 1.4e-11 43.9 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family MerR_1 PF13411.6 EMT51202.1 - 0.092 12.8 0.1 8.2 6.6 0.0 2.8 3 0 0 3 3 3 0 MerR HTH family regulatory protein DUF2201_N PF13203.6 EMT51203.1 - 1.7e-25 90.2 1.4 8.6e-16 58.3 1.4 3.1 2 1 0 2 2 2 2 Putative metallopeptidase domain DUF2201 PF09967.9 EMT51203.1 - 2.3e-06 27.7 0.0 4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 VWA-like domain (DUF2201) Peptidase_M48 PF01435.18 EMT51203.1 - 0.0032 17.3 0.1 0.058 13.2 0.1 2.1 2 0 0 2 2 2 1 Peptidase family M48 VWA_2 PF13519.6 EMT51203.1 - 0.18 12.5 0.0 0.48 11.1 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain AAA_5 PF07728.14 EMT51204.1 - 7.9e-12 45.4 0.0 1.6e-11 44.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EMT51204.1 - 8.7e-08 32.7 0.0 1.7e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT51204.1 - 3.2e-06 27.6 0.0 0.0011 19.4 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_3 PF07726.11 EMT51204.1 - 2.8e-05 24.0 0.0 5.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EMT51204.1 - 0.00058 19.1 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 EMT51204.1 - 0.016 15.2 0.0 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 EMT51204.1 - 0.019 14.7 0.0 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 EMT51204.1 - 0.031 14.5 0.0 0.091 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMT51204.1 - 0.039 14.4 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 RNA helicase RuvB_N PF05496.12 EMT51204.1 - 0.045 13.5 0.0 4.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EMT51204.1 - 0.07 12.5 0.0 6.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 EMT51204.1 - 0.084 13.0 0.1 1.7 8.8 0.0 2.8 3 1 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 EMT51204.1 - 0.12 11.9 0.0 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region IPT PF01745.16 EMT51204.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase AAA_24 PF13479.6 EMT51204.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EMT51204.1 - 0.19 11.8 0.0 0.62 10.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF3520 PF12034.8 EMT51205.1 - 3.2e-44 151.3 4.1 9.1e-43 146.5 4.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3520) vWF_A PF12450.8 EMT51205.1 - 1.4e-28 98.6 0.0 2.8e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor VWA PF00092.28 EMT51205.1 - 1.1e-21 77.9 0.0 1.9e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EMT51205.1 - 5e-17 62.3 0.0 8.1e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EMT51205.1 - 4.5e-16 59.4 0.0 1.3e-15 57.9 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Sec23_trunk PF04811.15 EMT51205.1 - 7.9e-06 25.6 0.0 3e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain VWA_CoxE PF05762.14 EMT51205.1 - 0.0051 16.2 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein TssR PF17643.1 EMT51205.1 - 0.059 11.3 0.0 0.083 10.8 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR vWA-TerF-like PF10138.9 EMT51205.1 - 0.09 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus DUF2167 PF09935.9 EMT51206.1 - 7.4e-75 251.2 0.2 9.1e-75 250.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2167) DAO PF01266.24 EMT51207.1 - 2.7e-51 175.2 0.0 3.1e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMT51207.1 - 2.9e-09 36.6 0.0 9.6e-06 25.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMT51207.1 - 1.4e-07 31.1 0.6 0.0004 19.7 0.4 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EMT51207.1 - 1.8e-06 28.1 0.6 6.6e-06 26.3 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMT51207.1 - 2.4e-06 26.5 0.8 0.039 12.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EMT51207.1 - 3.6e-06 26.3 2.1 2.8e-05 23.4 2.1 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMT51207.1 - 4.2e-05 23.0 3.4 0.011 15.0 1.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMT51207.1 - 6.7e-05 23.4 0.5 0.0013 19.2 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMT51207.1 - 0.00033 20.0 0.0 0.00093 18.5 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EMT51207.1 - 0.0039 16.6 0.6 0.0078 15.6 0.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EMT51207.1 - 0.016 14.3 1.6 0.034 13.2 0.7 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EMT51207.1 - 0.022 13.8 0.5 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EMT51207.1 - 0.076 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 EMT51207.1 - 0.089 12.4 0.3 0.18 11.4 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Mqo PF06039.15 EMT51207.1 - 0.097 11.2 0.1 1.9 6.9 0.1 2.3 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) MCPsignal PF00015.21 EMT51208.1 - 1.4e-51 174.7 45.7 1.6e-48 164.8 22.8 3.7 2 1 2 4 4 4 3 Methyl-accepting chemotaxis protein (MCP) signalling domain sCache_2 PF17200.4 EMT51208.1 - 5.7e-34 117.2 0.3 5.7e-34 117.2 0.3 4.1 5 1 0 5 5 5 1 Single Cache domain 2 dCache_2 PF08269.11 EMT51208.1 - 1.8e-18 66.8 0.0 1.8e-18 66.8 0.0 3.1 3 2 1 4 4 4 1 Cache domain HAMP PF00672.25 EMT51208.1 - 2.1e-13 50.4 7.0 2.3e-13 50.3 0.0 4.5 5 2 0 5 5 3 1 HAMP domain Cache_3-Cache_2 PF17201.4 EMT51208.1 - 4.4e-13 49.2 0.4 4.4e-13 49.2 0.4 3.9 4 0 0 4 4 4 1 Cache 3/Cache 2 fusion domain DUF948 PF06103.11 EMT51208.1 - 4.5e-06 26.8 26.8 0.15 12.3 0.6 5.3 2 2 2 4 4 4 3 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 EMT51208.1 - 0.00022 21.5 15.5 0.055 13.8 0.7 4.8 2 2 1 4 4 4 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 MAD PF05557.13 EMT51208.1 - 0.0013 17.2 0.5 0.0013 17.2 0.5 2.2 1 1 0 2 2 2 1 Mitotic checkpoint protein Laminin_II PF06009.12 EMT51208.1 - 0.0031 17.6 25.6 0.21 11.6 0.4 4.5 2 2 3 5 5 5 3 Laminin Domain II Med9 PF07544.13 EMT51208.1 - 0.0036 17.4 6.6 0.8 9.8 0.0 4.4 4 0 0 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.12 EMT51208.1 - 0.025 14.6 27.5 0.022 14.8 3.1 4.8 4 1 1 5 5 4 0 Protein of unknown function (DUF1664) Lipoprotein_7 PF01540.16 EMT51208.1 - 0.032 13.5 11.9 0.18 11.0 1.0 2.2 1 1 1 2 2 2 0 Adhesin lipoprotein Goodbye PF17109.5 EMT51208.1 - 0.043 14.3 0.9 0.043 14.3 0.9 3.9 2 2 2 4 4 4 0 fungal STAND N-terminal Goodbye domain Poty_PP PF08440.10 EMT51208.1 - 0.1 11.7 3.5 0.2 10.7 3.5 1.5 1 0 0 1 1 1 0 Potyviridae polyprotein Fib_alpha PF08702.10 EMT51208.1 - 0.11 12.7 12.0 6.5 6.9 0.8 4.5 3 1 0 4 4 4 0 Fibrinogen alpha/beta chain family T7SS_ESX_EspC PF10824.8 EMT51208.1 - 0.21 12.1 33.0 0.091 13.3 1.4 4.7 3 1 1 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm ApoLp-III PF07464.11 EMT51208.1 - 0.27 11.3 30.2 0.42 10.7 9.4 4.0 2 2 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Sec34 PF04136.15 EMT51208.1 - 0.27 11.1 12.0 15 5.4 0.2 4.5 4 1 1 5 5 4 0 Sec34-like family DotA PF11388.8 EMT51208.1 - 0.3 11.3 3.1 21 5.4 0.0 3.6 2 1 2 4 4 4 0 Phagosome trafficking protein DotA DASH_Dam1 PF08653.10 EMT51208.1 - 0.77 9.6 3.2 13 5.6 0.2 3.7 5 0 0 5 5 4 0 DASH complex subunit Dam1 Spc7 PF08317.11 EMT51208.1 - 0.93 8.3 17.8 1.8 7.3 0.3 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein JUPITER PF17054.5 EMT51208.1 - 0.96 8.9 6.4 0.11 11.9 0.7 2.0 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter DUF4473 PF14747.6 EMT51208.1 - 0.99 10.0 5.4 14 6.3 1.2 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Mod_r PF07200.13 EMT51208.1 - 1.2 9.3 14.1 5.7 7.0 0.2 3.8 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein AIP3 PF03915.13 EMT51208.1 - 1.3 8.0 21.7 0.17 10.9 2.4 2.2 1 1 0 2 2 2 0 Actin interacting protein 3 EF-G-binding_N PF07299.11 EMT51208.1 - 1.4 9.5 4.6 4.2 8.0 0.1 3.5 4 0 0 4 4 4 0 Elongation factor G-binding protein, N-terminal eIF3_N PF09440.10 EMT51208.1 - 1.8 9.0 10.3 8.9 6.8 0.3 3.7 2 2 2 4 4 4 0 eIF3 subunit 6 N terminal domain DASH_Dad1 PF08649.10 EMT51208.1 - 2.1 8.6 13.8 18 5.6 0.1 5.2 5 1 1 6 6 5 0 DASH complex subunit Dad1 ISG65-75 PF11727.8 EMT51208.1 - 3.6 6.7 21.8 3.5 6.8 3.6 3.0 1 1 2 3 3 3 0 Invariant surface glycoprotein DUF3450 PF11932.8 EMT51208.1 - 4.4 6.5 27.7 0.41 9.9 2.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Glu-tRNAGln PF02686.15 EMT51208.1 - 4.6 7.6 6.8 25 5.2 0.0 4.6 6 0 0 6 6 4 0 Glu-tRNAGln amidotransferase C subunit COG2 PF06148.11 EMT51208.1 - 5.2 7.2 21.0 4.9 7.3 1.9 5.1 3 2 4 7 7 6 0 COG (conserved oligomeric Golgi) complex component, COG2 CheZ PF04344.13 EMT51208.1 - 7.8 6.4 19.9 0.48 10.3 1.3 3.7 1 1 2 3 3 3 0 Chemotaxis phosphatase, CheZ Tup_N PF08581.10 EMT51208.1 - 9.6 6.6 6.5 8.5 6.8 0.1 3.5 4 0 0 4 4 3 0 Tup N-terminal zf-C4_ClpX PF06689.13 EMT51209.1 - 1.8e-10 40.5 0.7 3.5e-10 39.6 0.7 1.6 1 0 0 1 1 1 1 ClpX C4-type zinc finger Hpt PF01627.23 EMT51209.1 - 0.0056 16.9 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 1 Hpt domain zf-ribbon_3 PF13248.6 EMT51209.1 - 0.12 11.9 1.5 2.9 7.4 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain FTHFS PF01268.19 EMT51210.1 - 2.1e-248 825.1 0.0 2.3e-248 824.9 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase CbiA PF01656.23 EMT51210.1 - 0.029 14.4 0.0 0.18 11.8 0.4 2.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Bac_luciferase PF00296.20 EMT51211.1 - 5.2e-32 111.5 2.8 7.3e-32 111.0 2.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Methyltransf_PK PF05891.12 EMT51212.1 - 0.13 11.8 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MCPsignal PF00015.21 EMT51213.1 - 1e-30 106.8 11.9 1e-30 106.8 11.9 3.6 1 1 2 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 EMT51213.1 - 8.3e-05 22.9 0.6 0.00063 20.1 0.1 2.9 3 0 0 3 3 3 1 HAMP domain ApoLp-III PF07464.11 EMT51213.1 - 0.0081 16.3 7.0 0.0081 16.3 7.0 3.7 2 2 1 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Peptidase_M61 PF05299.12 EMT51213.1 - 0.0082 16.5 0.2 0.0082 16.5 0.2 2.7 2 1 0 2 2 2 1 M61 glycyl aminopeptidase Baculo_PEP_C PF04513.12 EMT51213.1 - 0.012 15.7 5.6 0.012 15.7 5.6 3.5 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Y1_Tnp PF01797.16 EMT51213.1 - 0.026 14.6 0.9 0.2 11.8 0.2 2.7 3 0 0 3 3 3 0 Transposase IS200 like Rep_trans PF02486.19 EMT51213.1 - 0.043 13.5 0.4 0.33 10.6 0.3 2.3 2 0 0 2 2 2 0 Replication initiation factor DUF2385 PF09539.10 EMT51213.1 - 0.16 12.5 2.1 0.87 10.1 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2385) DUF948 PF06103.11 EMT51213.1 - 0.53 10.6 28.6 0.85 9.9 3.0 5.7 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Serine_rich PF08824.10 EMT51213.1 - 1.5 8.9 16.7 0.33 10.9 1.5 4.2 2 1 3 5 5 5 0 Serine rich protein interaction domain Mt_ATP-synt_D PF05873.12 EMT51213.1 - 1.8 8.4 8.9 0.66 9.8 0.3 3.1 3 1 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Fez1 PF06818.15 EMT51213.1 - 3.1 8.2 19.8 0.67 10.4 9.9 2.7 1 1 1 2 2 2 0 Fez1 DASH_Duo1 PF08651.10 EMT51213.1 - 6.3 6.6 15.4 0.5 10.2 0.1 5.3 5 1 0 5 5 5 0 DASH complex subunit Duo1 Mce4_CUP1 PF11887.8 EMT51213.1 - 7.3 6.0 12.3 0.28 10.6 2.2 2.8 1 1 2 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative MCPsignal PF00015.21 EMT51214.1 - 1.2e-48 165.2 52.4 9.1e-47 159.1 23.1 4.2 2 1 2 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 EMT51214.1 - 2.4e-16 59.8 0.5 2.4e-16 59.8 0.5 4.1 5 1 0 5 5 3 1 HAMP domain 4HB_MCP_1 PF12729.7 EMT51214.1 - 2.9e-11 43.3 4.0 2.9e-11 43.3 4.0 3.9 3 2 1 4 4 4 1 Four helix bundle sensory module for signal transduction CHASE3 PF05227.13 EMT51214.1 - 4.2e-08 33.2 4.0 4.2e-08 33.2 4.0 4.0 2 1 2 4 4 4 1 CHASE3 domain BLOC1_2 PF10046.9 EMT51214.1 - 1.4e-07 31.7 24.4 0.00048 20.4 0.7 5.5 3 2 2 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EMT51214.1 - 5.1e-07 29.9 27.1 0.0042 17.3 1.5 6.5 3 3 3 6 6 6 5 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 EMT51214.1 - 0.0062 16.7 24.2 0.013 15.7 0.8 4.7 2 1 1 4 4 4 2 Seryl-tRNA synthetase N-terminal domain DASH_Dad4 PF08650.10 EMT51214.1 - 0.018 15.0 7.2 6.8 6.7 0.1 4.9 4 1 1 5 5 5 0 DASH complex subunit Dad4 Vps5 PF09325.10 EMT51214.1 - 0.019 14.5 1.0 0.019 14.5 1.0 3.8 2 1 1 4 4 4 0 Vps5 C terminal like DUF1871 PF08958.10 EMT51214.1 - 0.18 12.2 1.0 8.1 6.8 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF1871) Vip3A_N PF12495.8 EMT51214.1 - 0.27 11.1 5.3 0.48 10.3 0.0 3.4 4 1 0 5 5 4 0 Vegetative insecticide protein 3A N terminal SCO1-SenC PF02630.14 EMT51214.1 - 0.32 10.9 1.8 3.2 7.7 0.3 3.2 2 1 1 3 3 3 0 SCO1/SenC Glycophorin_A PF01102.18 EMT51214.1 - 0.5 10.6 0.0 0.5 10.6 0.0 3.0 3 1 0 3 3 3 0 Glycophorin A NPV_P10 PF05531.12 EMT51214.1 - 0.6 10.6 12.9 0.42 11.1 1.4 4.5 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 EMT51214.1 - 0.72 9.7 13.7 0.65 9.9 0.2 4.7 3 3 2 5 5 5 0 Sec34-like family BCDHK_Adom3 PF10436.9 EMT51214.1 - 1 9.2 12.4 0.13 12.1 0.3 3.3 2 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Flagellar_rod PF05149.12 EMT51214.1 - 1.1 8.7 19.7 0.019 14.5 2.6 3.5 2 1 0 3 3 3 0 Paraflagellar rod protein Syntaxin_2 PF14523.6 EMT51214.1 - 1.1 9.6 22.4 2.7 8.4 2.5 5.5 2 2 2 4 4 4 0 Syntaxin-like protein Sec8_exocyst PF04048.14 EMT51214.1 - 2.1 8.2 19.0 1.1 9.1 1.3 5.0 3 2 2 5 5 5 0 Sec8 exocyst complex component specific domain UPF0242 PF06785.11 EMT51214.1 - 3 7.9 19.1 4.5 7.3 1.3 3.5 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus ISG65-75 PF11727.8 EMT51214.1 - 3.8 6.7 23.0 0.025 13.8 4.9 3.5 3 2 1 4 4 4 0 Invariant surface glycoprotein Syntaxin-6_N PF09177.11 EMT51214.1 - 5.1 7.7 17.1 3.8 8.1 0.9 4.5 3 2 2 5 5 5 0 Syntaxin 6, N-terminal DUF2400 PF09674.10 EMT51214.1 - 6 6.8 9.9 1.6 8.7 0.3 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2400) DUF1043 PF06295.12 EMT51214.1 - 6.8 6.7 15.8 0.15 12.1 0.3 4.8 3 3 0 3 3 3 0 Protein of unknown function (DUF1043) DUF3818 PF12825.7 EMT51214.1 - 7.7 5.4 12.8 0.44 9.5 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function in PX-proteins (DUF3818) hemP PF10636.9 EMT51215.1 - 0.053 13.3 0.3 0.81 9.5 0.0 2.3 2 0 0 2 2 2 0 Hemin uptake protein hemP Amidase PF01425.21 EMT51216.1 - 4.8e-117 391.7 0.0 1e-116 390.6 0.0 1.5 1 1 0 1 1 1 1 Amidase Peptidase_M20 PF01546.28 EMT51217.1 - 1.3e-26 93.6 1.8 1.8e-26 93.1 1.8 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT51217.1 - 3.3e-09 36.6 0.1 8.4e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain ABC_tran PF00005.27 EMT51218.1 - 6.7e-33 114.1 0.0 8.9e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT51218.1 - 9.5e-20 70.9 0.2 1.6e-19 70.2 0.2 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EMT51218.1 - 0.001 18.5 0.0 0.0026 17.2 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT51218.1 - 0.0011 18.9 0.0 0.32 10.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMT51218.1 - 0.0045 17.4 0.0 0.0075 16.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Adeno_IVa2 PF02456.15 EMT51218.1 - 0.025 13.4 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Zeta_toxin PF06414.12 EMT51218.1 - 0.027 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 EMT51218.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EMT51218.1 - 0.066 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 EMT51218.1 - 0.093 12.8 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain PRK PF00485.18 EMT51218.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 EMT51218.1 - 0.15 11.7 0.1 0.13 11.9 0.1 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AIG1 PF04548.16 EMT51218.1 - 0.2 11.0 0.1 0.3 10.4 0.1 1.2 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.27 EMT51219.1 - 6.4e-27 94.7 0.0 9.6e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT51219.1 - 1.4e-20 73.6 0.1 2.5e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT51219.1 - 1.9e-05 24.6 0.1 5.6e-05 23.1 0.0 1.6 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51219.1 - 3.3e-05 23.4 0.0 7e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT51219.1 - 0.048 13.9 0.5 4.1 7.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EMT51219.1 - 0.089 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1177 PF06675.11 EMT51220.1 - 1.2e-137 457.2 0.7 1.3e-137 457.0 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1177) Peptidase_M20 PF01546.28 EMT51221.1 - 3.1e-35 121.8 0.0 9.5e-35 120.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT51221.1 - 3.8e-21 75.0 0.0 7.1e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT51221.1 - 0.0019 17.9 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M28 MORN PF02493.20 EMT51221.1 - 0.17 11.9 0.0 11 6.1 0.1 2.6 2 0 0 2 2 2 0 MORN repeat SBP_bac_5 PF00496.22 EMT51222.1 - 7.9e-101 337.7 4.9 1.1e-100 337.3 4.9 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 EMT51223.1 - 1.8e-31 109.3 8.8 1.8e-31 109.3 8.8 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT51223.1 - 5.3e-07 29.5 2.3 5.3e-07 29.5 2.3 2.3 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 EMT51224.1 - 3.7e-42 144.2 11.2 3.7e-42 144.2 11.2 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component EIF_2_alpha PF07541.12 EMT51225.1 - 0.025 14.7 0.1 0.035 14.2 0.1 1.3 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit PucR PF07905.11 EMT51227.1 - 4e-35 120.6 0.3 1.3e-34 119.0 0.1 2.0 2 0 0 2 2 2 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 EMT51227.1 - 1.9e-18 66.0 1.1 3.4e-18 65.2 0.2 1.9 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 EMT51227.1 - 2.1e-14 53.7 3.0 2.2e-14 53.7 0.4 2.3 2 1 0 2 2 2 1 GGDEF-like domain LpxI_C PF06230.11 EMT51227.1 - 0.054 13.3 0.1 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 LpxI C-terminal domain AroM PF07302.11 EMT51228.1 - 1.5e-82 276.2 0.0 1.7e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 AroM protein Hydrolase PF00702.26 EMT51228.1 - 0.028 14.7 0.0 0.032 14.5 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase S-methyl_trans PF02574.16 EMT51228.1 - 0.028 14.3 0.0 0.46 10.2 0.0 2.1 1 1 0 1 1 1 0 Homocysteine S-methyltransferase Asp_Glu_race PF01177.22 EMT51229.1 - 1.6e-12 47.7 0.2 8.5e-08 32.3 0.1 2.1 2 0 0 2 2 2 2 Asp/Glu/Hydantoin racemase Pantoate_transf PF02548.15 EMT51229.1 - 1.5e-07 31.1 1.6 1.4e-05 24.7 0.3 2.1 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase AroM PF07302.11 EMT51229.1 - 4.6e-05 22.9 0.2 7.3e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 AroM protein Amdase PF17645.1 EMT51229.1 - 0.0011 18.7 0.5 1.4 8.5 0.2 2.3 2 0 0 2 2 2 2 Arylmalonate decarboxylase DUF1266 PF06889.11 EMT51230.1 - 1.5e-38 132.6 3.7 1.5e-38 132.6 3.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1266) AIF-MLS PF14962.6 EMT51230.1 - 0.082 12.9 13.9 0.12 12.3 13.9 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence TPR_2 PF07719.17 EMT51231.1 - 3e-44 145.6 47.8 1.4e-05 24.8 0.0 15.9 15 1 1 16 16 15 10 Tetratricopeptide repeat TPR_1 PF00515.28 EMT51231.1 - 2.4e-36 122.1 33.2 1.6e-06 27.7 0.0 15.0 14 1 1 15 15 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 EMT51231.1 - 9.1e-36 122.2 28.4 1e-10 41.9 0.1 9.6 8 2 2 10 10 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 EMT51231.1 - 8.5e-35 116.0 27.3 3.8e-05 23.5 0.0 14.0 14 1 1 15 15 12 6 Tetratricopeptide repeat TPR_12 PF13424.6 EMT51231.1 - 3.6e-31 107.3 35.1 7.2e-08 32.6 1.5 10.5 7 4 3 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EMT51231.1 - 8.9e-31 106.0 22.0 5.7e-06 26.5 0.0 7.3 4 2 2 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EMT51231.1 - 5.1e-24 84.2 18.4 7.1e-05 22.9 0.0 8.4 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 EMT51231.1 - 2.4e-23 80.8 37.6 0.0016 19.1 0.0 14.3 8 4 7 15 15 13 7 Tetratricopeptide repeat TPR_16 PF13432.6 EMT51231.1 - 4.5e-23 81.6 23.5 4.2e-07 30.5 0.0 9.7 7 2 2 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 EMT51231.1 - 1.4e-20 72.7 24.6 4.5e-06 26.2 0.1 11.2 8 4 3 11 11 11 2 TPR repeat TPR_17 PF13431.6 EMT51231.1 - 2.4e-13 49.5 9.8 0.26 11.8 0.0 9.5 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMT51231.1 - 1.6e-12 46.5 41.7 0.38 10.9 0.0 13.4 15 1 0 15 15 12 6 Tetratricopeptide repeat TPR_6 PF13174.6 EMT51231.1 - 1.3e-11 44.4 28.6 1.3 9.8 0.0 13.1 12 2 1 13 13 12 2 Tetratricopeptide repeat TPR_15 PF13429.6 EMT51231.1 - 1e-09 38.0 7.0 0.0028 16.9 0.0 5.0 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 EMT51231.1 - 6.7e-07 29.3 5.3 3.6 8.5 0.1 8.0 9 0 0 9 9 6 1 Tetratricopeptide repeat DnaJ PF00226.31 EMT51231.1 - 1e-06 28.8 0.0 3.2e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_10 PF13374.6 EMT51231.1 - 4e-06 26.5 40.5 0.042 13.7 0.0 11.3 14 0 0 14 14 11 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMT51231.1 - 9.3e-06 25.6 27.3 0.031 14.3 0.2 8.4 8 0 0 8 8 8 1 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 EMT51231.1 - 2.6e-05 23.6 0.5 0.12 11.9 0.0 4.2 3 0 0 3 3 3 1 SHNi-TPR NARP1 PF12569.8 EMT51231.1 - 3.3e-05 23.0 8.6 0.17 10.8 0.1 4.4 4 1 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 EMT51231.1 - 3.8e-05 23.2 14.6 1.5 8.1 2.1 6.8 2 2 3 7 7 7 1 MalT-like TPR region Coatomer_E PF04733.14 EMT51231.1 - 6.5e-05 22.5 2.3 3.4 7.0 0.0 4.4 3 2 1 4 4 4 1 Coatomer epsilon subunit TPR_21 PF09976.9 EMT51231.1 - 8.9e-05 22.3 1.4 0.85 9.3 0.0 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat-like domain DUF627 PF04781.12 EMT51231.1 - 0.00031 20.7 0.1 0.012 15.6 0.1 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF627) PknG_TPR PF16918.5 EMT51231.1 - 0.00038 19.3 4.0 0.0029 16.4 0.0 3.0 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_20 PF14561.6 EMT51231.1 - 0.00075 19.8 8.8 0.024 15.0 0.0 5.0 4 1 3 7 7 6 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EMT51231.1 - 0.00087 19.8 0.2 1.9 8.9 0.0 3.5 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation BTAD PF03704.17 EMT51231.1 - 0.015 15.7 16.0 1 9.8 0.1 5.7 4 3 2 6 6 5 0 Bacterial transcriptional activator domain DUF1958 PF09211.10 EMT51231.1 - 0.029 14.7 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) DUF3856 PF12968.7 EMT51231.1 - 0.059 13.4 4.7 5.4 7.1 0.0 5.1 4 1 1 5 5 5 0 Domain of Unknown Function (DUF3856) DUF4698 PF15769.5 EMT51231.1 - 0.066 12.3 0.3 0.1 11.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) ChAPs PF09295.10 EMT51231.1 - 0.2 10.6 1.3 17 4.2 0.0 2.9 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.20 EMT51231.1 - 1.2 9.5 10.0 21 5.6 0.0 6.6 9 0 0 9 9 6 0 PPR repeat R3H-assoc PF13902.6 EMT51231.1 - 1.5 9.2 3.3 2.1 8.8 1.3 2.2 2 0 0 2 2 1 0 R3H-associated N-terminal domain HSP70 PF00012.20 EMT51232.1 - 1e-128 430.2 0.1 1.7e-118 396.4 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EMT51232.1 - 4.2e-12 45.5 0.0 7e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 EMT51232.1 - 0.00026 20.8 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 EMT51232.1 - 0.0068 15.7 0.0 0.027 13.7 0.0 2.0 2 0 0 2 2 2 1 StbA protein WG_beta_rep PF14903.6 EMT51233.1 - 1e-42 144.0 6.6 2.9e-10 40.2 0.1 8.8 9 0 0 9 9 9 6 WG containing repeat DUF3298 PF11738.8 EMT51233.1 - 1.5e-20 74.0 3.6 7.5e-19 68.6 2.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3298) PdaC PF13739.6 EMT51233.1 - 0.0002 22.2 0.6 0.00084 20.3 0.1 2.3 2 1 0 2 2 2 1 Deacetylase PdaC TPR_9 PF13371.6 EMT51233.1 - 0.012 15.7 0.9 0.044 13.9 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EMT51233.1 - 0.025 15.1 4.6 0.072 13.6 0.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 EMT51233.1 - 0.062 13.6 0.9 0.14 12.5 0.9 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMT51233.1 - 0.1 13.5 0.7 0.43 11.5 0.2 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF2375 PF09558.10 EMT51233.1 - 0.18 11.9 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2375) HATPase_c PF02518.26 EMT51234.1 - 2.8e-22 79.3 0.3 6e-22 78.3 0.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT51234.1 - 2.9e-13 49.7 0.2 1.7e-12 47.1 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain STAS PF01740.21 EMT51234.1 - 5.7e-07 29.2 0.2 2e-06 27.4 0.1 1.9 2 0 0 2 2 2 1 STAS domain HATPase_c_5 PF14501.6 EMT51234.1 - 6.1e-07 29.3 0.0 1.7e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 EMT51234.1 - 5.5e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NOG1 PF06858.14 EMT51234.1 - 0.099 12.4 0.2 2.1 8.2 0.0 3.1 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) HATPase_c_2 PF13581.6 EMT51234.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Cass2 PF14526.6 EMT51235.1 - 7.1e-22 78.2 0.0 8.4e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Integron-associated effector binding protein GyrI-like PF06445.15 EMT51235.1 - 8.2e-20 71.7 0.2 9.1e-20 71.5 0.2 1.0 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Adenine_glyco PF03352.13 EMT51236.1 - 2.1e-85 284.9 0.1 2.5e-85 284.7 0.1 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase HhH-GPD PF00730.25 EMT51236.1 - 0.03 14.8 0.0 0.038 14.5 0.0 1.3 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein adh_short_C2 PF13561.6 EMT51237.1 - 1.3e-51 175.5 0.0 1.4e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT51237.1 - 4e-51 173.3 0.1 4.7e-51 173.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT51237.1 - 2.7e-13 50.2 0.1 3.8e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMT51237.1 - 0.0006 19.3 0.0 0.0027 17.2 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EMT51237.1 - 0.0014 18.9 0.1 0.0026 18.0 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EMT51237.1 - 0.0016 18.3 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EMT51237.1 - 0.0037 16.5 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EMT51237.1 - 0.0039 16.3 0.0 0.0076 15.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 EMT51237.1 - 0.0059 17.2 0.0 0.0099 16.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent QSOX_Trx1 PF18108.1 EMT51237.1 - 0.14 12.3 0.1 0.9 9.7 0.0 2.2 2 0 0 2 2 2 0 QSOX Trx-like domain 3HCDH_N PF02737.18 EMT51237.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PEP-utilizers_C PF02896.18 EMT51237.1 - 0.16 11.1 0.0 0.31 10.1 0.0 1.4 2 0 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain Acyl_transf_3 PF01757.22 EMT51238.1 - 5.1e-12 45.5 54.3 6.9e-12 45.1 54.3 1.1 1 0 0 1 1 1 1 Acyltransferase family EII-Sor PF03609.14 EMT51238.1 - 0.17 11.3 12.8 0.071 12.5 1.3 2.9 2 1 0 2 2 2 0 PTS system sorbose-specific iic component DNA_binding_1 PF01035.20 EMT51239.1 - 3e-22 78.5 0.1 3.6e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Isochorismatase PF00857.20 EMT51240.1 - 8.4e-33 114.0 1.0 9.7e-33 113.8 1.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Acetyltransf_1 PF00583.25 EMT51241.1 - 8.5e-10 38.9 0.0 8.2e-07 29.3 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EMT51241.1 - 3.7e-06 27.7 0.0 0.0023 18.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT51241.1 - 0.0015 18.6 0.0 0.011 15.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMT51241.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT51241.1 - 0.077 13.4 0.0 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SnoaL_2 PF12680.7 EMT51242.1 - 1.2e-09 38.7 0.0 1.4e-09 38.5 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EMT51242.1 - 9.7e-07 28.6 0.0 2.2e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 EMT51242.1 - 0.0026 18.2 0.0 0.0036 17.7 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) NTF2 PF02136.20 EMT51242.1 - 0.041 14.5 0.0 0.05 14.2 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Nitroreductase PF00881.24 EMT51243.1 - 7.4e-24 84.7 0.0 9.1e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family CytB6-F_Fe-S PF08802.10 EMT51243.1 - 0.35 10.9 5.0 13 5.9 0.2 3.5 4 0 0 4 4 4 0 Cytochrome B6-F complex Fe-S subunit LysR_substrate PF03466.20 EMT51244.1 - 4e-31 108.0 0.0 5.6e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT51244.1 - 1.6e-21 76.0 0.3 2.6e-21 75.3 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 EMT51244.1 - 0.0097 15.8 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 EMT51244.1 - 0.11 12.8 0.2 0.45 10.7 0.0 2.0 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Cu_amine_oxidN1 PF07833.11 EMT51245.1 - 3.5e-13 49.9 5.4 4.5e-07 30.3 1.1 1.8 1 1 1 2 2 2 2 Copper amine oxidase N-terminal domain ABC_tran_CTD PF16326.5 EMT51245.1 - 9.7e-05 22.5 1.1 0.00025 21.2 1.1 1.7 1 0 0 1 1 1 1 ABC transporter C-terminal domain PKcGMP_CC PF16808.5 EMT51245.1 - 0.0003 20.6 3.8 0.0003 20.6 3.8 2.7 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DivIC PF04977.15 EMT51245.1 - 0.00037 20.2 3.9 0.00074 19.2 3.2 1.9 1 1 0 1 1 1 1 Septum formation initiator DUF5082 PF16888.5 EMT51245.1 - 0.0005 20.4 3.2 0.001 19.3 3.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) TMF_DNA_bd PF12329.8 EMT51245.1 - 0.00055 19.9 0.7 0.00055 19.9 0.7 1.8 2 0 0 2 2 1 1 TATA element modulatory factor 1 DNA binding Cast PF10174.9 EMT51245.1 - 0.0013 17.0 1.4 0.0019 16.5 1.4 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Med4 PF10018.9 EMT51245.1 - 0.0035 17.0 0.4 0.0057 16.4 0.4 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 ATG16 PF08614.11 EMT51245.1 - 0.012 15.9 1.2 0.018 15.3 1.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1192 PF06698.11 EMT51245.1 - 0.012 15.7 2.2 0.2 11.7 0.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Csm1_N PF18504.1 EMT51245.1 - 0.012 15.9 1.0 0.012 15.9 1.0 1.7 2 0 0 2 2 1 0 Csm1 N-terminal domain SlyX PF04102.12 EMT51245.1 - 0.014 16.0 2.6 0.12 13.0 0.6 2.5 2 1 2 4 4 3 0 SlyX DUF16 PF01519.16 EMT51245.1 - 0.018 15.5 4.1 0.02 15.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 BBP1_C PF15272.6 EMT51245.1 - 0.032 14.1 6.6 0.1 12.4 6.6 1.8 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF4407 PF14362.6 EMT51245.1 - 0.034 13.5 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 EMT51245.1 - 0.035 14.2 3.4 0.11 12.7 3.5 1.6 1 1 0 1 1 1 0 Tropomyosin like BRE1 PF08647.11 EMT51245.1 - 0.042 13.9 1.1 0.076 13.1 0.3 1.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase MPS2 PF17060.5 EMT51245.1 - 0.05 12.9 6.0 1.1 8.4 0.4 2.1 2 0 0 2 2 2 0 Monopolar spindle protein 2 MnmE_helical PF12631.7 EMT51245.1 - 0.052 13.7 4.3 2.6 8.2 1.6 2.3 2 0 0 2 2 2 0 MnmE helical domain SseC PF04888.12 EMT51245.1 - 0.053 13.1 0.1 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Lebercilin PF15619.6 EMT51245.1 - 0.057 13.1 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 EMT51245.1 - 0.058 12.3 1.2 0.064 12.1 0.2 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein GrpE PF01025.19 EMT51245.1 - 0.063 12.9 3.4 0.096 12.3 0.5 2.1 2 0 0 2 2 2 0 GrpE ACCA PF03255.14 EMT51245.1 - 0.08 12.8 0.6 0.14 12.1 0.2 1.6 2 0 0 2 2 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Fib_alpha PF08702.10 EMT51245.1 - 0.08 13.1 1.2 0.31 11.2 0.1 2.3 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family Shugoshin_N PF07558.11 EMT51245.1 - 0.093 12.6 0.2 0.26 11.2 0.0 1.8 2 0 0 2 2 1 0 Shugoshin N-terminal coiled-coil region FlaC_arch PF05377.11 EMT51245.1 - 0.095 13.1 2.2 0.54 10.7 0.4 2.8 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) FlxA PF14282.6 EMT51245.1 - 0.11 12.5 1.3 0.16 11.9 0.4 1.7 2 0 0 2 2 1 0 FlxA-like protein CEP209_CC5 PF16574.5 EMT51245.1 - 0.13 12.4 1.9 0.22 11.7 1.3 1.6 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 Herpes_UL25 PF01499.16 EMT51245.1 - 0.14 10.6 0.1 0.2 10.1 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Swi5 PF07061.11 EMT51245.1 - 0.16 12.1 1.3 0.25 11.4 0.4 1.8 2 0 0 2 2 1 0 Swi5 DMPK_coil PF08826.10 EMT51245.1 - 0.18 11.9 0.8 0.54 10.4 0.8 1.8 1 1 0 1 1 1 0 DMPK coiled coil domain like UPF0242 PF06785.11 EMT51245.1 - 0.19 11.8 0.3 0.19 11.8 0.3 1.7 3 0 0 3 3 1 0 Uncharacterised protein family (UPF0242) N-terminus CLZ PF16526.5 EMT51245.1 - 0.2 12.0 2.2 0.81 10.1 2.0 2.0 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fez1 PF06818.15 EMT51245.1 - 0.22 12.0 1.2 0.38 11.2 1.2 1.3 1 1 0 1 1 1 0 Fez1 Prefoldin_2 PF01920.20 EMT51245.1 - 0.29 11.1 2.3 0.74 9.8 0.8 2.1 2 1 1 3 3 2 0 Prefoldin subunit DUF3375 PF11855.8 EMT51245.1 - 0.35 9.7 4.8 0.76 8.6 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Atg14 PF10186.9 EMT51245.1 - 0.37 9.8 0.4 0.55 9.3 0.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 EMT51245.1 - 0.4 11.2 3.2 0.4 11.2 2.0 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4140 PF13600.6 EMT51245.1 - 0.98 9.9 5.3 0.52 10.8 2.8 1.9 2 1 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) HSBP1 PF06825.12 EMT51245.1 - 1.7 8.6 13.2 3.5 7.6 1.8 2.7 1 1 1 2 2 2 0 Heat shock factor binding protein 1 DUF465 PF04325.13 EMT51245.1 - 2 8.5 12.5 0.2 11.7 2.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF465) NPV_P10 PF05531.12 EMT51245.1 - 9.2 6.8 11.1 12 6.5 6.8 2.8 3 1 1 4 4 2 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 EMT51245.1 - 9.3 6.5 11.4 0.66 10.2 1.0 2.9 2 1 2 4 4 4 0 Haemolysin XhlA Response_reg PF00072.24 EMT51246.1 - 4.3e-26 91.3 0.0 6.5e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT51246.1 - 2.1e-24 85.4 0.4 4.8e-24 84.2 0.4 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal RELT PF12606.8 EMT51246.1 - 5.9e-05 22.0 0.0 0.042 12.8 0.0 2.3 2 0 0 2 2 2 2 Tumour necrosis factor receptor superfamily member 19 HTH_11 PF08279.12 EMT51246.1 - 0.00029 20.7 2.3 0.00069 19.5 0.6 2.6 2 1 0 2 2 2 1 HTH domain GerE PF00196.19 EMT51246.1 - 0.09 12.3 0.0 4.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Transglut_core2 PF13369.6 EMT51246.1 - 0.13 11.8 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily HATPase_c PF02518.26 EMT51247.1 - 1.3e-28 99.7 0.0 2.3e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT51247.1 - 2.6e-12 46.6 0.6 5.9e-12 45.4 0.1 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EMT51247.1 - 0.00042 20.2 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EMT51247.1 - 0.0062 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 GHKL domain bPH_5 PF10882.8 EMT51247.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial PH domain DUF4220 PF13968.6 EMT51247.1 - 0.12 11.8 0.6 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) DUF347 PF03988.12 EMT51247.1 - 0.36 11.1 3.8 0.46 10.7 0.1 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) PDR_CDR PF06422.12 EMT51247.1 - 0.38 10.7 0.1 0.38 10.7 0.1 2.2 2 0 0 2 2 2 0 CDR ABC transporter TarH PF02203.15 EMT51247.1 - 0.38 10.7 2.6 0.28 11.1 0.2 1.9 2 0 0 2 2 2 0 Tar ligand binding domain homologue Sigma_reg_N PF13800.6 EMT51247.1 - 0.61 10.4 4.8 4.4 7.7 0.5 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal MatE PF01554.18 EMT51247.1 - 0.72 9.5 5.7 0.56 9.9 1.4 2.2 2 0 0 2 2 2 0 MatE ABC_tran PF00005.27 EMT51248.1 - 5.9e-22 78.7 0.0 8.3e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT51248.1 - 0.00098 18.6 0.2 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT51248.1 - 0.0012 19.1 0.2 0.0052 17.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMT51248.1 - 0.0013 18.5 0.2 0.0067 16.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT51248.1 - 0.0031 17.9 0.1 0.0047 17.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EMT51248.1 - 0.012 16.1 0.1 0.032 14.7 0.1 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EMT51248.1 - 0.012 16.2 0.6 0.023 15.3 0.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EMT51248.1 - 0.014 15.3 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EMT51248.1 - 0.018 14.6 0.3 0.038 13.6 0.2 1.9 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 EMT51248.1 - 0.065 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EMT51248.1 - 0.068 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 EMT51248.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain PduV-EutP PF10662.9 EMT51248.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EMT51248.1 - 0.11 12.7 0.3 0.12 12.6 0.3 1.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EMT51248.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 EMT51248.1 - 0.13 12.0 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EMT51248.1 - 0.13 12.2 0.0 1.8 8.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EMT51248.1 - 0.16 12.0 0.2 0.41 10.7 0.2 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EMT51248.1 - 0.21 10.8 1.5 0.75 8.9 0.3 1.9 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 EMT51249.1 - 5.6e-21 75.5 0.0 8e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT51249.1 - 1e-13 51.6 0.2 2.5e-13 50.3 0.1 1.8 2 0 0 2 2 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT51249.1 - 3.6e-05 23.7 0.5 0.0059 16.5 0.0 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMT51249.1 - 0.00092 19.6 0.2 0.0015 19.0 0.2 1.3 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EMT51249.1 - 0.0022 17.5 0.1 0.023 14.1 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 EMT51249.1 - 0.0074 15.7 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EMT51249.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 EMT51249.1 - 0.027 14.2 0.3 0.051 13.3 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT51249.1 - 0.18 12.1 0.1 0.44 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EMT51249.1 - 0.22 11.4 0.1 0.35 10.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 EMT51249.1 - 0.23 10.6 0.1 0.33 10.1 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain BPD_transp_1 PF00528.22 EMT51250.1 - 8.6e-22 77.8 12.5 8.6e-22 77.8 12.5 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EMT51251.1 - 5.6e-40 137.0 9.8 5.6e-40 137.0 9.8 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 EMT51252.1 - 2.5e-76 257.1 3.7 4e-76 256.4 3.7 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DcrB PF08786.11 EMT51254.1 - 0.002 18.3 0.1 0.0034 17.5 0.1 1.4 1 0 0 1 1 1 1 DcrB LPAM_1 PF08139.12 EMT51254.1 - 0.15 12.6 4.3 0.39 11.3 4.3 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site LAGLIDADG_3 PF14528.6 EMT51254.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 LAGLIDADG-like domain DUF2680 PF10925.8 EMT51254.1 - 1 9.4 4.9 1.3 9.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) FTP PF07504.13 EMT51255.1 - 3e-10 39.8 3.3 5.3e-06 26.2 0.2 3.1 3 0 0 3 3 3 2 Fungalysin/Thermolysin Propeptide Motif DUF4901 PF16244.5 EMT51255.1 - 1e-09 38.1 0.4 0.033 13.5 0.0 4.3 2 2 0 3 3 3 3 Domain of unknown function (DUF4901) PepSY PF03413.19 EMT51255.1 - 0.00088 19.8 14.4 0.66 10.6 0.1 6.3 7 1 0 7 7 7 2 Peptidase propeptide and YPEB domain HTH_Tnp_Tc5 PF03221.16 EMT51255.1 - 0.0031 17.5 0.0 0.27 11.3 0.0 2.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain KR PF08659.10 EMT51255.1 - 0.0043 17.0 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 KR domain tRNA-synt_His PF13393.6 EMT51255.1 - 0.049 12.9 1.0 0.12 11.7 0.6 1.8 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Sigma70_r4_2 PF08281.12 EMT51256.1 - 1.4e-15 56.6 1.4 4.3e-15 55.1 0.9 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT51256.1 - 3.2e-13 49.2 0.2 6.5e-13 48.3 0.2 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EMT51256.1 - 7e-11 41.5 1.7 2.7e-10 39.6 0.5 2.4 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT51256.1 - 0.00012 22.1 2.2 0.00012 22.0 0.2 1.9 2 1 0 2 2 2 1 ECF sigma factor UPF0122 PF04297.14 EMT51256.1 - 0.00014 22.0 1.0 0.0005 20.3 0.1 2.1 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_23 PF13384.6 EMT51256.1 - 0.00025 20.8 1.1 0.0013 18.5 0.3 2.5 2 1 0 2 2 2 1 Homeodomain-like domain Phage_antitermQ PF06530.12 EMT51256.1 - 0.00025 20.9 0.1 0.00046 20.1 0.1 1.5 1 0 0 1 1 1 1 Phage antitermination protein Q GerE PF00196.19 EMT51256.1 - 0.0011 18.5 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family DUF134 PF02001.16 EMT51256.1 - 0.018 15.6 0.1 0.039 14.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF134 IF2_N PF04760.15 EMT51256.1 - 0.018 14.8 1.3 3.7 7.5 0.2 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region HTH_38 PF13936.6 EMT51256.1 - 0.028 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TnsD PF15978.5 EMT51256.1 - 0.035 13.1 0.6 0.63 9.0 0.1 2.2 2 0 0 2 2 2 0 Tn7-like transposition protein D HTH_29 PF13551.6 EMT51256.1 - 0.038 14.0 0.1 0.076 13.0 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Phage_terminase PF10668.9 EMT51256.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Phage terminase small subunit HTH_11 PF08279.12 EMT51256.1 - 0.052 13.5 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 HTH domain PHZA_PHZB PF03284.13 EMT51256.1 - 0.068 12.8 0.2 1.6 8.3 0.0 2.3 1 1 0 2 2 2 0 Phenazine biosynthesis protein A/B MADF_DNA_bdg PF10545.9 EMT51256.1 - 0.14 12.5 2.5 0.61 10.4 0.2 2.5 2 2 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PCI PF01399.27 EMT51256.1 - 0.21 12.1 1.6 0.9 10.1 0.1 2.2 2 1 0 2 2 2 0 PCI domain Ribosomal_L5 PF00281.19 EMT51257.1 - 0.094 13.1 1.6 2.4 8.5 0.2 3.0 3 0 0 3 3 3 0 Ribosomal protein L5 DoxX PF07681.12 EMT51258.1 - 3.4e-10 40.4 7.0 3.4e-10 40.4 7.0 2.2 1 1 1 2 2 2 1 DoxX DoxD PF04173.13 EMT51258.1 - 0.00037 20.4 5.9 0.00099 19.1 5.9 1.7 1 1 0 1 1 1 1 TQO small subunit DoxD Polysacc_deac_1 PF01522.21 EMT51259.1 - 1.4e-52 176.8 2.0 1.5e-30 105.7 0.2 2.6 3 0 0 3 3 3 2 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EMT51259.1 - 6e-05 22.4 2.9 0.14 11.3 0.2 3.0 2 2 0 2 2 2 2 Glycosyl hydrolase family 57 Polysacc_deac_2 PF04748.13 EMT51259.1 - 0.0042 16.3 1.2 0.035 13.3 0.1 2.8 3 1 0 3 3 3 1 Divergent polysaccharide deacetylase UPF0180 PF03698.13 EMT51259.1 - 0.023 14.9 0.1 0.44 10.7 0.0 3.2 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0180) GFRP PF06399.13 EMT51259.1 - 0.025 14.4 0.0 3.1 7.7 0.0 2.9 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) MucBP_2 PF17965.1 EMT51259.1 - 0.034 14.7 0.8 22 5.7 0.0 3.4 2 1 1 3 3 3 0 Mucin binding domain AlaDh_PNT_N PF05222.15 EMT51259.1 - 0.046 14.0 0.1 4.6 7.5 0.0 3.5 4 1 1 5 5 5 0 Alanine dehydrogenase/PNT, N-terminal domain DUF2334 PF10096.9 EMT51259.1 - 0.52 9.9 3.7 6.2 6.4 0.4 3.2 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2334) FGGY_N PF00370.21 EMT51260.1 - 1.3e-63 214.9 0.0 1.7e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EMT51260.1 - 1.3e-37 129.4 0.1 2.1e-37 128.8 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EMT51260.1 - 0.028 13.9 0.0 0.088 12.3 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family HTH_6 PF01418.17 EMT51261.1 - 7.9e-22 77.0 0.0 7.4e-21 73.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 EMT51261.1 - 1.5e-19 70.1 0.1 3.1e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 EMT51261.1 - 4.7e-08 33.1 0.9 5.9e-06 26.3 0.3 2.4 1 1 1 2 2 2 2 SIS domain PHP PF02811.19 EMT51261.1 - 0.044 14.1 0.0 0.26 11.6 0.0 2.2 2 0 0 2 2 2 0 PHP domain DUF2529 PF10740.9 EMT51261.1 - 0.086 12.5 0.1 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2529) NAD_binding_2 PF03446.15 EMT51262.1 - 5.5e-43 146.9 0.0 7.8e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.19 EMT51262.1 - 2.4e-22 79.7 0.5 1.4e-21 77.2 0.5 2.8 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EMT51262.1 - 4.2e-05 23.2 0.2 6.9e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EMT51262.1 - 0.00013 22.4 0.0 0.00024 21.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EMT51262.1 - 0.0082 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 EMT51262.1 - 0.032 14.5 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Rossmann-like PF10727.9 EMT51262.1 - 0.039 13.8 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain HTH_11 PF08279.12 EMT51262.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 HTH domain ApbA PF02558.16 EMT51262.1 - 0.071 12.7 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA BPD_transp_1 PF00528.22 EMT51263.1 - 2.4e-30 105.7 12.7 2.6e-30 105.6 9.5 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT51263.1 - 3e-13 49.5 0.1 3e-13 49.5 0.1 3.5 3 1 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 EMT51264.1 - 3.4e-42 144.3 9.7 3.4e-42 144.3 9.7 1.7 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2157 PF09925.9 EMT51264.1 - 0.024 14.4 4.8 2.6 7.8 0.0 2.7 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) DUF1304 PF06993.12 EMT51264.1 - 0.48 10.4 5.6 0.22 11.5 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) ABC_tran PF00005.27 EMT51265.1 - 6.6e-32 110.9 0.0 9.1e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT51265.1 - 1.9e-19 69.9 0.3 3.5e-19 69.1 0.3 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EMT51265.1 - 0.0002 20.9 0.1 0.0004 19.9 0.1 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT51265.1 - 0.0055 16.5 0.6 0.14 11.9 0.1 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMT51265.1 - 0.008 16.6 0.0 0.019 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 EMT51265.1 - 0.012 15.0 0.0 0.029 13.7 0.0 1.7 2 0 0 2 2 2 0 AIG1 family ATP-synt_ab PF00006.25 EMT51265.1 - 0.023 14.3 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.6 EMT51265.1 - 0.041 12.5 0.0 0.072 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EMT51265.1 - 0.088 13.2 0.1 0.45 10.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMT51265.1 - 0.19 12.0 1.0 0.47 10.7 1.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMT51266.1 - 1e-30 107.0 0.0 1.5e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT51266.1 - 1.7e-22 79.7 0.2 3.6e-22 78.6 0.2 1.6 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EMT51266.1 - 3.8e-05 23.2 0.1 9.1e-05 22.0 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT51266.1 - 7.5e-05 22.7 0.1 0.00016 21.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMT51266.1 - 0.0081 16.4 0.9 3.1 8.1 0.1 2.2 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 EMT51266.1 - 0.35 10.2 1.8 0.94 8.9 0.2 2.3 2 1 1 3 3 3 0 Bacterial TniB protein Peptidase_M20 PF01546.28 EMT51267.1 - 2.1e-33 115.8 1.5 3.3e-33 115.1 1.5 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT51267.1 - 2.1e-11 43.7 0.1 4.7e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT51267.1 - 0.0013 18.5 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 OSR1_C PF12202.8 EMT51267.1 - 0.16 12.2 0.0 0.46 10.7 0.0 1.7 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain SBP_bac_5 PF00496.22 EMT51268.1 - 3.1e-111 372.0 5.0 4e-111 371.6 5.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF3558 PF12079.8 EMT51268.1 - 0.11 12.5 0.3 0.18 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) LPAM_1 PF08139.12 EMT51268.1 - 0.44 11.1 3.6 1.1 9.9 3.6 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF2207 PF09972.9 EMT51269.1 - 1.2 7.8 2.6 1.4 7.6 2.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SBP_bac_5 PF00496.22 EMT51270.1 - 1.3e-84 284.4 9.8 1.3e-84 284.4 9.8 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF3841 PF12952.7 EMT51270.1 - 0.1 12.4 1.3 0.87 9.4 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3841) Response_reg PF00072.24 EMT51272.1 - 0.00012 22.2 0.9 0.0095 16.1 0.0 2.0 1 1 1 2 2 2 2 Response regulator receiver domain EF-G-binding_N PF07299.11 EMT51273.1 - 4e-24 84.9 1.2 8.5e-24 83.9 1.2 1.6 1 0 0 1 1 1 1 Elongation factor G-binding protein, N-terminal FBP_C PF16571.5 EMT51273.1 - 9.6e-12 44.7 0.0 1.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 FBP C-terminal treble-clef zinc-finger NfI_DNAbd_pre-N PF10524.9 EMT51273.1 - 0.019 14.8 0.5 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 Nuclear factor I protein pre-N-terminus DUF3306 PF11748.8 EMT51273.1 - 0.15 13.0 0.1 0.22 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Mor PF08765.11 EMT51274.1 - 0.00021 21.2 0.1 0.0033 17.4 0.1 2.0 1 1 0 1 1 1 1 Mor transcription activator family LLC1 PF14945.6 EMT51274.1 - 0.009 16.6 0.1 0.011 16.4 0.1 1.1 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein DNA_pol3_a_NI PF14480.6 EMT51274.1 - 0.49 10.4 3.0 3 7.9 0.1 2.6 2 1 1 3 3 3 0 DNA polymerase III polC-type N-terminus I Ribosom_S30AE_C PF16321.5 EMT51275.1 - 5.3e-29 99.7 0.1 9.9e-29 98.8 0.1 1.5 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus Ribosomal_S30AE PF02482.19 EMT51275.1 - 7.8e-29 100.3 0.2 1.2e-28 99.7 0.2 1.3 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein DUF3810 PF12725.7 EMT51275.1 - 0.064 12.6 0.1 0.079 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) CorA PF01544.18 EMT51275.1 - 0.1 11.9 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Herpes_LMP1 PF05297.11 EMT51276.1 - 0.045 13.0 6.0 0.051 12.8 6.0 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Pox_A14 PF05767.12 EMT51276.1 - 0.1 12.8 2.1 0.13 12.4 2.1 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Peptidase_U32 PF01136.19 EMT51277.1 - 7e-97 323.2 0.0 1e-96 322.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family U32 Peptidase_U32_C PF16325.5 EMT51277.1 - 1.8e-27 95.4 0.0 3.8e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family U32 C-terminal domain Peptidase_U32 PF01136.19 EMT51278.1 - 7.4e-57 192.2 0.0 2.1e-56 190.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family U32 UDG PF03167.19 EMT51279.1 - 9.3e-23 80.9 0.0 1.1e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Nramp PF01566.18 EMT51280.1 - 5.8e-115 384.1 27.0 8.7e-115 383.5 27.0 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Pyr_redox_2 PF07992.14 EMT51281.1 - 1.1e-65 221.8 6.7 1.4e-65 221.4 6.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EMT51281.1 - 1.2e-32 112.5 0.3 2.4e-32 111.5 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EMT51281.1 - 1.7e-23 83.0 7.9 1.5e-19 70.3 0.5 3.1 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMT51281.1 - 3.4e-16 59.3 4.9 2e-11 43.6 0.2 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMT51281.1 - 1.1e-15 57.8 2.0 3.2e-15 56.2 2.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMT51281.1 - 4.2e-11 42.9 9.7 6.6e-10 38.9 1.3 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EMT51281.1 - 5.1e-10 38.6 11.5 2e-06 26.8 1.0 3.8 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 EMT51281.1 - 2.4e-09 37.3 2.6 0.00039 20.6 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EMT51281.1 - 5.3e-09 35.7 7.0 0.00018 20.8 0.5 3.1 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EMT51281.1 - 2.2e-08 34.1 18.7 0.0047 16.6 3.6 4.2 2 2 2 4 4 4 4 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMT51281.1 - 1.3e-07 31.1 16.7 2.6e-07 30.1 2.0 3.8 3 1 1 4 4 4 2 FAD binding domain Lycopene_cycl PF05834.12 EMT51281.1 - 2.2e-06 27.0 5.2 0.25 10.3 0.1 3.3 2 1 1 3 3 3 3 Lycopene cyclase protein FAD_binding_3 PF01494.19 EMT51281.1 - 3.5e-06 26.5 10.5 0.00096 18.5 0.4 3.3 2 1 1 3 3 3 2 FAD binding domain Trp_halogenase PF04820.14 EMT51281.1 - 3.4e-05 22.9 5.0 7.8e-05 21.7 0.7 2.3 2 0 0 2 2 2 1 Tryptophan halogenase 3HCDH_N PF02737.18 EMT51281.1 - 0.00013 21.9 2.9 0.0064 16.4 0.4 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EMT51281.1 - 0.00037 20.9 3.5 0.19 12.1 0.1 2.8 3 0 0 3 3 2 2 Putative NAD(P)-binding Thi4 PF01946.17 EMT51281.1 - 0.0019 17.5 2.4 0.011 14.9 0.3 2.5 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 EMT51281.1 - 0.0035 16.7 0.3 0.043 13.2 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EMT51281.1 - 0.0039 16.8 1.1 2 7.9 0.1 2.5 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 EMT51281.1 - 0.0066 16.9 0.1 1.5 9.3 0.0 2.5 2 0 0 2 2 2 1 XdhC Rossmann domain TrkA_N PF02254.18 EMT51281.1 - 0.023 15.0 2.3 3.4 8.0 0.4 3.1 2 0 0 2 2 2 0 TrkA-N domain 2-oxoacid_dh PF00198.23 EMT51282.1 - 3.2e-80 268.9 0.0 4.7e-80 268.4 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EMT51282.1 - 7.4e-16 57.7 2.7 1.7e-15 56.6 2.7 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EMT51282.1 - 1.9e-15 56.9 0.1 4.4e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain HlyD_3 PF13437.6 EMT51282.1 - 0.069 13.8 1.1 2.7 8.7 0.1 2.8 1 1 1 2 2 2 0 HlyD family secretion protein DUF3597 PF12200.8 EMT51282.1 - 0.27 11.8 11.4 1.7 9.2 2.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Transket_pyr PF02779.24 EMT51283.1 - 6.3e-57 192.1 0.1 8.6e-57 191.7 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMT51283.1 - 4.3e-43 146.2 0.1 8.3e-43 145.2 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EMT51283.1 - 2e-05 24.8 0.0 3.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Alba PF01918.21 EMT51283.1 - 0.17 11.7 0.4 0.5 10.2 0.1 1.8 2 0 0 2 2 2 0 Alba E1_dh PF00676.20 EMT51284.1 - 1.5e-91 306.5 0.0 1.7e-91 306.3 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EMT51284.1 - 3.2e-08 33.5 0.4 1.6e-07 31.3 0.4 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 EMT51284.1 - 0.00053 19.0 0.0 0.00078 18.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 EMT51284.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.6 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase BPL_LplA_LipB PF03099.19 EMT51285.1 - 5.3e-10 39.3 0.0 7.5e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Sigma54_activat PF00158.26 EMT51286.1 - 7.1e-66 221.1 0.0 1.9e-65 219.6 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT51286.1 - 1.7e-20 73.6 0.0 1.4e-19 70.6 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 EMT51286.1 - 6.7e-14 51.4 0.1 1.6e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family GAF PF01590.26 EMT51286.1 - 9.8e-09 35.9 0.0 3.3e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 GAF domain AAA_5 PF07728.14 EMT51286.1 - 2.3e-06 27.6 0.0 4.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMT51286.1 - 0.00019 20.9 0.0 0.0056 16.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI HTH_23 PF13384.6 EMT51286.1 - 0.00035 20.3 0.0 0.00086 19.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain AAA PF00004.29 EMT51286.1 - 0.001 19.5 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 EMT51286.1 - 0.0014 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_28 PF13518.6 EMT51286.1 - 0.003 17.6 0.0 0.0071 16.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0175 PF03683.13 EMT51286.1 - 0.03 14.0 0.1 0.065 13.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) IclR PF01614.18 EMT51286.1 - 0.064 13.1 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial transcriptional regulator PAS_4 PF08448.10 EMT51286.1 - 0.069 13.4 0.0 14 6.0 0.0 2.8 2 0 0 2 2 2 0 PAS fold dCache_1 PF02743.18 EMT51286.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cache domain sCache_3_2 PF17203.4 EMT51286.1 - 0.17 12.0 0.0 0.64 10.1 0.0 1.9 2 0 0 2 2 2 0 Single cache domain 3 Sigma70_r4 PF04545.16 EMT51287.1 - 4.8e-16 58.0 0.0 9.9e-16 57.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EMT51287.1 - 4.8e-14 51.8 0.0 2.7e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT51287.1 - 3.3e-08 33.2 1.1 5.9e-08 32.4 1.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 EMT51287.1 - 2.9e-07 30.5 1.0 6.8e-07 29.4 1.0 1.5 1 1 0 1 1 1 1 ECF sigma factor UPF0122 PF04297.14 EMT51287.1 - 0.0031 17.7 0.3 0.032 14.5 0.0 2.4 2 1 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_23 PF13384.6 EMT51287.1 - 0.11 12.3 0.5 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain RPAP1_N PF08621.10 EMT51288.1 - 0.033 14.0 1.1 7.1 6.5 0.1 3.9 4 0 0 4 4 4 0 RPAP1-like, N-terminal DUF2383 PF09537.10 EMT51288.1 - 0.06 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) TCTP PF00838.17 EMT51288.1 - 0.099 13.0 3.4 0.41 11.0 0.1 2.2 2 0 0 2 2 2 0 Translationally controlled tumour protein UPF0122 PF04297.14 EMT51288.1 - 0.13 12.5 0.9 0.34 11.2 0.3 2.0 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_40 PF14493.6 EMT51288.1 - 1.4 9.4 4.9 4.4 7.8 0.5 3.6 5 0 0 5 5 5 0 Helix-turn-helix domain DUF4179 PF13786.6 EMT51289.1 - 2.4e-14 53.6 0.3 5.8e-14 52.3 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) zf-HC2 PF13490.6 EMT51289.1 - 4.3e-07 30.1 0.2 1e-06 28.9 0.2 1.6 1 0 0 1 1 1 1 Putative zinc-finger DUF5643 PF18705.1 EMT51289.1 - 1.4e-05 25.0 1.0 0.0041 17.1 0.0 4.0 3 1 1 4 4 4 1 Family of unknown function (DUF5643) Glyco_hydro_2 PF00703.21 EMT51289.1 - 0.055 14.1 1.5 3.2 8.5 0.0 3.3 3 0 0 3 3 3 0 Glycosyl hydrolases family 2 Sigma70_r4_2 PF08281.12 EMT51290.1 - 1.4e-14 53.5 0.4 3.5e-14 52.2 0.4 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT51290.1 - 2.8e-14 52.6 0.1 4.4e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EMT51290.1 - 1.3e-12 47.1 0.6 3e-12 45.9 0.6 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT51290.1 - 7.4e-06 26.0 0.4 4.2e-05 23.5 0.4 2.0 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 EMT51290.1 - 0.0014 18.4 0.3 0.0031 17.2 0.0 1.7 2 0 0 2 2 1 1 Homeodomain-like domain HTH_24 PF13412.6 EMT51290.1 - 0.0024 17.4 0.2 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding DUF1492 PF07374.11 EMT51290.1 - 0.015 15.4 0.3 0.028 14.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) HTH_16 PF12645.7 EMT51290.1 - 0.02 14.9 0.1 0.051 13.6 0.1 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain Trp_repressor PF01371.19 EMT51290.1 - 0.02 15.0 0.7 0.045 13.9 0.2 1.9 2 0 0 2 2 2 0 Trp repressor protein HTH_AsnC-type PF13404.6 EMT51290.1 - 0.02 14.7 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Creatinase_N PF01321.18 EMT51290.1 - 0.022 15.4 0.0 0.032 14.9 0.0 1.2 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain GerE PF00196.19 EMT51290.1 - 0.025 14.1 0.7 0.054 13.1 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Phage_antitermQ PF06530.12 EMT51290.1 - 0.083 12.8 0.6 0.26 11.2 0.2 2.1 2 1 0 2 2 2 0 Phage antitermination protein Q HTH_17 PF12728.7 EMT51290.1 - 0.096 12.9 0.2 0.26 11.5 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_20 PF12840.7 EMT51290.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain SDF PF00375.18 EMT51291.1 - 5.3e-98 328.6 32.8 5.3e-98 328.6 32.8 1.4 2 0 0 2 2 2 1 Sodium:dicarboxylate symporter family Rhodanese PF00581.20 EMT51293.1 - 2.2e-19 70.0 0.0 3.9e-14 53.1 0.0 2.5 2 0 0 2 2 2 2 Rhodanese-like domain Lactamase_B PF00753.27 EMT51293.1 - 3.1e-12 46.9 0.8 7.7e-12 45.6 0.8 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Pyr_redox_2 PF07992.14 EMT51294.1 - 8.9e-17 61.2 0.1 2e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMT51294.1 - 5.1e-05 23.0 2.0 0.025 14.1 0.2 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMT51294.1 - 0.00078 19.5 0.1 0.02 14.9 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EMT51294.1 - 0.0013 17.9 0.3 0.047 12.7 0.1 2.3 1 1 1 2 2 2 1 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 EMT51294.1 - 0.0076 16.5 0.0 0.029 14.6 0.0 2.0 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 EMT51294.1 - 0.03 14.9 1.8 2.7 8.6 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMT51294.1 - 0.073 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EMT51294.1 - 0.079 12.2 0.2 4.1 6.6 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMT51294.1 - 0.16 10.8 0.1 0.25 10.1 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 EMT51294.1 - 0.21 10.3 0.2 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein TauE PF01925.19 EMT51295.1 - 1.2e-06 28.3 0.8 1.3e-06 28.2 0.8 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF3335 PF11814.8 EMT51295.1 - 0.13 11.7 0.2 0.16 11.4 0.2 1.1 1 0 0 1 1 1 0 Peptidase_C39 like family SRAP PF02586.14 EMT51296.1 - 3.2e-69 232.8 0.0 3.7e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Ank_5 PF13857.6 EMT51297.1 - 3.3e-13 49.6 1.0 1.2e-08 35.1 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMT51297.1 - 1.4e-08 35.2 0.0 1.9e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMT51297.1 - 7.2e-07 29.6 0.0 1e-05 26.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EMT51297.1 - 7.8e-06 26.1 0.0 0.00037 20.8 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EMT51297.1 - 2.3e-05 24.4 0.1 0.00065 20.0 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat SpoIISA_toxin PF14171.6 EMT51297.1 - 0.036 13.7 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Erythro_esteras PF05139.14 EMT51299.1 - 1.3e-73 248.7 1.7 1.6e-73 248.5 1.7 1.0 1 0 0 1 1 1 1 Erythromycin esterase HeLo PF14479.6 EMT51299.1 - 0.086 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation 3-dmu-9_3-mt PF06983.13 EMT51300.1 - 7.5e-09 36.2 0.0 9.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyoxalase PF00903.25 EMT51300.1 - 2.7e-05 24.3 0.0 3.1e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_8 PF13181.6 EMT51300.1 - 0.043 14.0 0.1 1.5 9.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Syncollin PF15138.6 EMT51300.1 - 0.073 13.3 0.0 0.17 12.1 0.0 1.5 2 0 0 2 2 2 0 Syncollin TPR_7 PF13176.6 EMT51300.1 - 0.19 11.9 0.1 1.7 8.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_20 PF12840.7 EMT51301.1 - 1.2e-13 50.9 1.1 1.7e-13 50.4 1.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EMT51301.1 - 2.6e-12 46.4 0.1 4.9e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 EMT51301.1 - 0.00016 21.5 0.2 0.00024 20.9 0.2 1.3 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 EMT51301.1 - 0.00048 19.9 0.9 0.0011 18.7 0.9 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 EMT51301.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 EMT51301.1 - 0.0015 18.5 0.1 0.0022 17.9 0.1 1.3 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 EMT51301.1 - 0.0018 18.2 0.1 0.0029 17.5 0.1 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 EMT51301.1 - 0.0077 16.6 0.1 0.011 16.0 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator RP-C PF03428.13 EMT51301.1 - 0.012 15.3 0.1 0.035 13.8 0.0 1.7 2 0 0 2 2 2 0 Replication protein C N-terminal domain TrmB PF01978.19 EMT51301.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 EMT51301.1 - 0.037 14.5 0.3 0.061 13.8 0.3 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain PaaX PF07848.12 EMT51301.1 - 0.047 13.9 0.3 0.12 12.6 0.1 1.7 1 1 1 2 2 2 0 PaaX-like protein Cdc6_C PF09079.11 EMT51301.1 - 0.063 13.3 0.2 0.52 10.3 0.0 2.0 1 1 1 2 2 2 0 CDC6, C terminal winged helix domain FUR PF01475.19 EMT51301.1 - 0.072 13.2 0.1 0.11 12.6 0.1 1.3 1 1 0 1 1 1 0 Ferric uptake regulator family AHSA1 PF08327.11 EMT51302.1 - 3e-23 82.4 1.7 3.4e-23 82.2 1.7 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EMT51302.1 - 2.3e-06 27.9 0.2 2.7e-06 27.7 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF3284 PF11687.8 EMT51302.1 - 0.15 12.0 0.0 0.19 11.6 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3284) SBP_bac_5 PF00496.22 EMT51303.1 - 3.4e-83 279.7 13.5 4.8e-83 279.2 13.5 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Endonuc-BglII PF09195.11 EMT51303.1 - 0.069 13.0 1.2 0.097 12.5 0.1 1.7 2 0 0 2 2 2 0 Restriction endonuclease BglII ABC_tran PF00005.27 EMT51304.1 - 2.6e-31 109.0 0.0 4e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT51304.1 - 2.3e-17 63.3 0.4 4e-17 62.5 0.4 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EMT51304.1 - 1.2e-05 24.8 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT51304.1 - 0.0085 16.4 1.0 0.053 13.8 1.0 2.0 1 1 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 EMT51304.1 - 0.019 14.6 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 EMT51304.1 - 0.04 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 EMT51304.1 - 0.04 13.7 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 EMT51304.1 - 0.048 13.6 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 EMT51304.1 - 0.054 13.6 0.0 0.079 13.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 EMT51304.1 - 0.055 13.3 0.3 1.5 8.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMT51304.1 - 0.059 13.8 0.7 0.096 13.1 0.7 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF2813 PF11398.8 EMT51304.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) ABC_tran PF00005.27 EMT51305.1 - 5.3e-32 111.2 0.0 8.5e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT51305.1 - 5.9e-23 81.2 0.1 1.1e-22 80.3 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EMT51305.1 - 7.3e-08 32.1 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT51305.1 - 1.1e-07 32.0 0.0 1.7e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMT51305.1 - 0.00044 20.5 1.2 0.0072 16.6 1.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT51305.1 - 0.00047 20.6 0.1 0.00095 19.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EMT51305.1 - 0.00098 19.6 0.6 0.017 15.6 0.0 2.2 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EMT51305.1 - 0.0011 18.4 0.0 0.0091 15.4 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 EMT51305.1 - 0.0069 15.8 0.8 0.64 9.4 0.4 2.4 2 1 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 EMT51305.1 - 0.02 14.6 0.2 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EMT51305.1 - 0.05 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 EMT51305.1 - 0.078 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EMT51305.1 - 0.078 12.7 0.3 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EMT51305.1 - 0.11 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.25 EMT51305.1 - 0.14 11.8 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 EMT51305.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EMT51305.1 - 0.16 11.6 0.2 6.3 6.4 0.1 2.1 1 1 0 2 2 2 0 AAA ATPase domain BPD_transp_1 PF00528.22 EMT51306.1 - 3.2e-31 108.5 9.9 3.2e-31 108.5 9.9 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT51306.1 - 2.7e-16 59.3 0.0 2.7e-16 59.3 0.0 3.6 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 EMT51307.1 - 1.2e-36 126.2 16.9 1.2e-36 126.2 16.9 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Renin_r PF07850.14 EMT51307.1 - 0.065 13.8 1.0 0.065 13.8 1.0 2.7 3 0 0 3 3 3 0 Renin receptor-like protein HTH_29 PF13551.6 EMT51308.1 - 0.0001 22.2 0.1 0.027 14.5 0.5 2.4 2 0 0 2 2 2 2 Winged helix-turn helix HTH_28 PF13518.6 EMT51308.1 - 0.002 18.2 0.1 0.99 9.6 0.1 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EMT51308.1 - 0.0047 17.2 0.5 0.048 14.0 0.5 2.4 1 1 0 1 1 1 1 Transposase HTH_32 PF13565.6 EMT51308.1 - 0.011 16.3 0.7 0.017 15.7 0.7 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_23 PF13384.6 EMT51308.1 - 0.013 15.3 0.0 0.94 9.4 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HAD_2 PF13419.6 EMT51309.1 - 1.6e-10 41.3 0.1 1.6e-09 38.1 0.1 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMT51309.1 - 1.7e-07 31.7 0.0 8.1e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMT51309.1 - 8.2e-05 23.1 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMT51309.1 - 0.00034 20.6 0.0 0.00094 19.2 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like 5_nucleotid PF05761.14 EMT51309.1 - 0.015 14.2 0.0 4.2 6.2 0.0 2.3 2 1 0 2 2 2 0 5' nucleotidase family PGP_phosphatase PF09419.10 EMT51309.1 - 0.048 13.3 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase BID PF06393.11 EMT51309.1 - 0.058 12.9 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) BPD_transp_1 PF00528.22 EMT51310.1 - 6.6e-18 65.1 15.5 6.6e-18 65.1 15.5 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component UL41A PF17591.2 EMT51310.1 - 0.25 11.4 1.7 1.6 8.9 0.6 2.5 1 1 1 2 2 2 0 Herpesvirus UL41A BPD_transp_1 PF00528.22 EMT51311.1 - 9e-14 51.6 26.2 9e-14 51.6 26.2 2.0 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_1 PF01547.25 EMT51312.1 - 2.8e-44 152.4 5.0 3.9e-44 151.9 5.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EMT51312.1 - 1.1e-42 146.8 0.8 1.4e-42 146.4 0.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EMT51312.1 - 2.3e-07 30.5 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EMT51312.1 - 0.00014 21.7 0.0 0.00053 19.8 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein LPAM_1 PF08139.12 EMT51312.1 - 0.17 12.4 1.4 0.32 11.6 1.4 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Cpn60_TCP1 PF00118.24 EMT51313.1 - 2.1e-101 340.0 21.1 3.1e-101 339.4 21.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FrhB_FdhB_N PF04422.13 EMT51313.1 - 0.0074 16.4 0.6 0.69 10.1 0.2 2.8 2 0 0 2 2 2 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term ATP-cone PF03477.16 EMT51313.1 - 0.82 10.3 4.3 38 5.0 0.9 3.4 2 1 0 2 2 2 0 ATP cone domain FliT PF05400.13 EMT51313.1 - 1.5 9.7 5.2 8.9 7.2 0.1 2.7 2 0 0 2 2 2 0 Flagellar protein FliT Cpn10 PF00166.21 EMT51314.1 - 1.2e-37 127.9 0.5 1.3e-37 127.7 0.5 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit MazE_antitoxin PF04014.18 EMT51314.1 - 0.057 13.4 0.5 5.8 7.0 0.0 2.7 3 0 0 3 3 3 0 Antidote-toxin recognition MazE, bacterial antitoxin CAP_assoc_N PF14504.6 EMT51315.1 - 3.7e-35 120.7 0.0 5.4e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 CAP-associated N-terminal CAP PF00188.26 EMT51315.1 - 1.9e-17 64.3 0.1 5.5e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family SmpA_OmlA PF04355.13 EMT51315.1 - 0.02 14.6 0.0 0.059 13.2 0.0 1.8 1 0 0 1 1 1 0 SmpA / OmlA family TatC PF00902.18 EMT51317.1 - 1.3e-53 181.9 22.8 1.5e-53 181.7 22.8 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) ASC PF00858.24 EMT51317.1 - 0.31 9.9 0.0 0.45 9.4 0.0 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel MttA_Hcf106 PF02416.16 EMT51318.1 - 3.1e-21 74.4 1.7 4.4e-21 73.9 1.7 1.6 1 1 0 1 1 1 1 mttA/Hcf106 family SART-1 PF03343.13 EMT51318.1 - 0.004 15.8 12.7 0.0042 15.7 12.7 1.0 1 0 0 1 1 1 1 SART-1 family APH PF01636.23 EMT51318.1 - 0.0096 15.9 1.4 0.011 15.6 1.4 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4834 PF16118.5 EMT51318.1 - 0.024 15.6 0.0 0.035 15.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2220 PF09983.9 EMT51318.1 - 0.31 10.4 6.4 0.36 10.2 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Spore_III_AF PF09581.10 EMT51318.1 - 0.81 9.7 8.3 1.2 9.1 8.3 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) MoCF_biosynth PF00994.24 EMT51319.1 - 1.8e-20 73.0 0.2 1e-19 70.6 0.1 2.0 2 0 0 2 2 2 1 Probable molybdopterin binding domain MoCF_biosynth PF00994.24 EMT51320.1 - 8.6e-31 106.5 0.0 1.1e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain 5-FTHF_cyc-lig PF01812.20 EMT51321.1 - 6.9e-41 140.2 0.0 7.7e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family ABC_tran PF00005.27 EMT51322.1 - 2.1e-52 177.2 4.9 4.5e-27 95.2 0.0 3.4 4 0 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EMT51322.1 - 2e-31 107.8 30.1 1.2e-27 95.8 8.3 3.0 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EMT51322.1 - 1.2e-18 68.0 12.8 3e-06 27.3 0.0 4.8 4 2 1 6 6 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51322.1 - 3.8e-12 46.1 0.0 0.0003 20.3 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_CTD PF16326.5 EMT51322.1 - 1.9e-09 37.7 11.9 1.9e-09 37.7 11.9 4.6 3 1 1 4 4 4 2 ABC transporter C-terminal domain AAA_22 PF13401.6 EMT51322.1 - 1.4e-08 35.1 0.0 0.0019 18.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 EMT51322.1 - 2.9e-08 33.8 0.5 0.0012 18.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 EMT51322.1 - 1.7e-07 31.5 2.9 0.035 14.3 0.0 3.7 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 EMT51322.1 - 3.6e-07 30.3 1.3 0.012 15.7 0.1 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EMT51322.1 - 6.6e-07 29.0 0.3 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 EMT51322.1 - 1.8e-05 24.6 0.0 0.088 12.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 EMT51322.1 - 1.8e-05 23.9 0.4 0.011 14.7 0.1 2.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 EMT51322.1 - 1.8e-05 25.1 0.2 0.4 11.1 0.0 3.9 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT51322.1 - 2.7e-05 24.6 4.8 0.026 14.9 0.0 3.4 4 0 0 4 4 3 2 AAA ATPase domain NACHT PF05729.12 EMT51322.1 - 3.7e-05 23.7 0.7 0.027 14.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 EMT51322.1 - 6e-05 23.6 0.8 0.14 12.8 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 EMT51322.1 - 7.5e-05 22.8 0.4 0.088 12.8 0.0 3.8 3 2 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EMT51322.1 - 0.00015 21.3 0.1 0.071 12.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 EMT51322.1 - 0.00016 21.7 0.1 1 9.3 0.0 3.1 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EMT51322.1 - 0.00016 22.0 0.0 0.35 11.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 EMT51322.1 - 0.00029 20.1 6.8 0.003 16.8 0.0 3.1 3 1 0 3 3 2 1 NB-ARC domain AAA_30 PF13604.6 EMT51322.1 - 0.00044 20.0 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EMT51322.1 - 0.00053 20.0 0.0 0.94 9.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EMT51322.1 - 0.0018 18.2 0.0 0.84 9.5 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain Roc PF08477.13 EMT51322.1 - 0.0032 17.7 0.1 0.69 10.1 0.0 3.2 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EMT51322.1 - 0.0038 17.2 0.7 0.25 11.3 0.1 2.6 2 0 0 2 2 2 1 NTPase Dynamin_N PF00350.23 EMT51322.1 - 0.0059 16.7 5.8 1.3 9.0 0.6 4.1 3 1 0 3 3 3 1 Dynamin family AAA_11 PF13086.6 EMT51322.1 - 0.0093 15.8 2.6 6.8 6.4 1.2 3.2 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EMT51322.1 - 0.0096 15.7 0.0 0.75 9.5 0.0 3.0 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.13 EMT51322.1 - 0.011 15.0 0.0 5.5 6.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 EMT51322.1 - 0.013 15.8 8.7 0.31 11.3 0.0 3.6 4 0 0 4 4 3 0 AAA domain AAA_27 PF13514.6 EMT51322.1 - 0.021 14.4 6.0 1.4 8.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 EMT51322.1 - 0.033 13.8 0.5 5.1 6.7 0.1 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Septin PF00735.18 EMT51322.1 - 0.041 13.2 0.0 2.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.12 EMT51322.1 - 0.042 13.1 3.2 0.36 10.1 0.1 3.0 3 0 0 3 3 3 0 Zeta toxin RuvB_N PF05496.12 EMT51322.1 - 0.054 13.2 0.3 8.6 6.1 0.0 2.9 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain MukB PF04310.12 EMT51322.1 - 0.057 13.2 0.1 12 5.7 0.1 2.6 2 0 0 2 2 2 0 MukB N-terminal MobB PF03205.14 EMT51322.1 - 0.079 12.9 0.4 19 5.1 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 EMT51322.1 - 0.083 12.5 0.7 5.4 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 EMT51322.1 - 0.083 12.3 0.0 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 EMT51322.1 - 0.13 12.0 0.4 18 5.0 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EMT51322.1 - 0.14 11.9 0.2 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 EMT51322.1 - 0.14 11.8 0.0 7.4 6.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 EMT51322.1 - 0.15 11.9 0.0 0.15 11.9 0.0 3.5 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea cobW PF02492.19 EMT51322.1 - 0.15 11.6 1.6 9.7 5.7 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 EMT51322.1 - 0.3 10.8 0.0 0.3 10.8 0.0 4.5 3 2 1 5 5 4 0 AAA ATPase domain DUF87 PF01935.17 EMT51322.1 - 0.49 10.5 14.4 1.8 8.6 0.1 4.4 4 1 0 4 4 4 0 Helicase HerA, central domain Cytidylate_kin PF02224.18 EMT51322.1 - 0.63 9.7 10.0 3 7.5 0.0 3.9 4 0 0 4 4 3 0 Cytidylate kinase AAA_23 PF13476.6 EMT51322.1 - 1.1 9.8 39.6 2.2 8.7 0.2 4.9 3 2 1 4 4 3 0 AAA domain RNA_pol_Rpb2_2 PF04561.14 EMT51322.1 - 1.1 8.9 6.7 7.2 6.2 0.3 2.7 2 1 0 2 2 2 0 RNA polymerase Rpb2, domain 2 Exonuc_VII_L PF02601.15 EMT51322.1 - 4 6.9 13.1 1.4 8.4 0.5 2.5 3 0 0 3 3 2 0 Exonuclease VII, large subunit Mitoc_mL59 PF18126.1 EMT51322.1 - 5 7.4 6.9 0.42 10.9 1.6 1.9 2 0 0 2 2 1 0 Mitochondrial ribosomal protein mL59 AAA_17 PF13207.6 EMT51322.1 - 5.5 7.4 13.9 3.3 8.1 0.1 4.0 4 0 0 4 4 3 0 AAA domain DUF1980 PF09323.10 EMT51323.1 - 0.47 10.3 1.4 6.3 6.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Peptidase_M22 PF00814.25 EMT51324.1 - 4.2e-106 354.6 0.1 4.9e-106 354.4 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EMT51324.1 - 5.6e-05 22.9 0.1 0.00019 21.2 0.0 1.8 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus BcrAD_BadFG PF01869.20 EMT51324.1 - 0.0027 17.2 0.0 0.0051 16.3 0.0 1.5 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family DUF3526 PF12040.8 EMT51324.1 - 0.014 15.9 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) baeRF_family2 PF18844.1 EMT51324.1 - 0.028 14.5 0.2 0.087 12.9 0.2 1.8 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 Dodecin PF07311.12 EMT51324.1 - 0.059 13.6 0.4 1.5 9.1 0.0 3.1 4 0 0 4 4 4 0 Dodecin Acetyltransf_1 PF00583.25 EMT51325.1 - 1.4e-18 67.3 0.0 1.7e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT51325.1 - 5.2e-14 52.4 0.0 7.2e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT51325.1 - 9.3e-13 48.2 0.0 1.2e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT51325.1 - 1e-08 35.0 0.1 1.3e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EMT51325.1 - 3.4e-06 27.2 0.1 9.2e-05 22.5 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMT51325.1 - 0.00048 20.8 0.0 0.00065 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EMT51325.1 - 0.00075 19.7 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMT51325.1 - 0.00095 18.9 0.1 0.0026 17.4 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT51325.1 - 0.029 14.5 0.0 0.036 14.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT51325.1 - 0.033 14.3 0.0 0.093 12.9 0.0 1.8 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 EMT51325.1 - 0.054 13.1 0.0 0.091 12.3 0.0 1.5 1 1 0 1 1 1 0 GNAT acetyltransferase Peptidase_M22 PF00814.25 EMT51326.1 - 1.3e-30 107.0 0.0 1.9e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family TsaE PF02367.17 EMT51327.1 - 1.7e-35 121.8 0.0 2e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 EMT51327.1 - 0.023 14.5 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase NACHT PF05729.12 EMT51327.1 - 0.028 14.3 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 EMT51327.1 - 0.1 12.1 0.1 0.18 11.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMT51327.1 - 0.11 13.0 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMT51327.1 - 0.14 12.7 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AIRS PF00586.24 EMT51328.1 - 1.5e-21 76.8 1.0 3.5e-21 75.6 1.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 EMT51328.1 - 8.3e-09 35.8 0.4 1.4e-08 35.0 0.4 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain SprT-like PF10263.9 EMT51329.1 - 3.5e-12 46.2 0.1 4.8e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 EMT51329.1 - 5.1e-05 23.1 9.2 5.1e-05 23.1 9.2 1.9 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zinc_ribbon_10 PF10058.9 EMT51329.1 - 0.00033 20.3 0.4 0.0006 19.5 0.4 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.10 EMT51329.1 - 0.047 13.8 2.0 0.098 12.8 2.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Trimer_CC PF08954.11 EMT51330.1 - 0.035 13.7 0.6 10 5.8 0.0 2.7 2 1 1 3 3 3 0 Trimerisation motif GreA_GreB_N PF03449.15 EMT51330.1 - 0.12 12.5 0.8 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal GIT_CC PF16559.5 EMT51330.1 - 0.33 10.9 2.4 9.4 6.2 0.1 2.5 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor LINES_C PF14695.6 EMT51330.1 - 0.34 10.4 2.1 2.7 7.5 0.1 2.6 2 1 0 2 2 2 0 Lines C-terminus Tex_N PF09371.10 EMT51332.1 - 9.9e-73 243.7 9.4 2.1e-72 242.6 9.4 1.6 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 EMT51332.1 - 1.6e-56 190.2 0.9 3e-56 189.3 0.2 1.9 2 0 0 2 2 2 1 Tex protein YqgF-like domain HHH_3 PF12836.7 EMT51332.1 - 2.2e-25 88.7 0.0 5.6e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 EMT51332.1 - 7.4e-22 78.0 0.1 6.5e-21 75.0 0.1 2.8 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 EMT51332.1 - 2.4e-11 43.8 1.4 4.6e-11 42.9 0.5 2.0 2 0 0 2 2 2 1 S1 RNA binding domain HHH_7 PF14635.6 EMT51332.1 - 5.6e-08 33.1 0.1 1.6e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif YqgF PF14639.6 EMT51332.1 - 7.7e-07 29.0 0.2 3e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_6 PF14579.6 EMT51332.1 - 0.0046 17.2 0.0 0.019 15.2 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF4164 PF13747.6 EMT51332.1 - 2 8.7 9.9 0.25 11.6 4.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Sigma70_r4 PF04545.16 EMT51333.1 - 4.9e-17 61.2 3.2 2.7e-16 58.8 1.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT51333.1 - 5.5e-17 61.3 0.0 1.2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 EMT51333.1 - 4.4e-14 52.3 0.6 9.6e-14 51.2 0.2 1.8 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 EMT51333.1 - 3.2e-07 29.9 2.5 5.3e-06 26.0 0.5 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 DUF134 PF02001.16 EMT51333.1 - 0.00014 22.3 0.1 0.0034 17.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function DUF134 HTH_37 PF13744.6 EMT51333.1 - 0.0007 19.5 0.3 0.0045 16.9 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EMT51333.1 - 0.00099 18.8 0.2 0.02 14.7 0.1 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 EMT51333.1 - 0.003 17.5 0.6 0.12 12.4 0.2 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_3 PF01381.22 EMT51333.1 - 0.0049 16.9 0.1 0.081 13.0 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 EMT51333.1 - 0.0098 16.2 0.3 0.083 13.3 0.1 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain KORA PF16509.5 EMT51333.1 - 0.039 14.2 0.1 0.14 12.5 0.1 1.9 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor HATPase_c_2 PF13581.6 EMT51334.1 - 2.4e-28 98.6 0.0 2.8e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 EMT51334.1 - 4.4e-07 30.4 0.0 5.7e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase STAS_2 PF13466.6 EMT51335.1 - 3.4e-17 62.6 0.0 3.9e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 EMT51335.1 - 3.4e-16 58.9 0.0 4.1e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 STAS domain SpoIIE PF07228.12 EMT51336.1 - 2.1e-45 155.0 0.0 2.8e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) RsbU_N PF08673.10 EMT51336.1 - 1.5e-21 76.3 0.0 3.4e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoserine phosphatase RsbU, N-terminal domain HATPase_c PF02518.26 EMT51337.1 - 3.4e-05 24.3 0.0 5.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT51337.1 - 3.5e-05 23.8 0.0 4.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PemK_toxin PF02452.17 EMT51338.1 - 3.3e-33 114.4 0.1 3.6e-33 114.3 0.1 1.0 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system HicB_lk_antitox PF15919.5 EMT51339.1 - 3.9e-06 27.0 0.1 7e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_1 PF01402.21 EMT51339.1 - 1.6e-05 24.7 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RHH_8 PF17723.1 EMT51339.1 - 0.0086 16.3 0.1 0.0088 16.2 0.1 1.1 1 0 0 1 1 1 1 Ribbon-Helix-Helix transcriptional regulator family PCI PF01399.27 EMT51339.1 - 0.0093 16.5 0.2 0.01 16.3 0.2 1.1 1 0 0 1 1 1 1 PCI domain PIN_4 PF13638.6 EMT51339.1 - 0.016 15.5 0.2 0.017 15.4 0.2 1.1 1 0 0 1 1 1 0 PIN domain RHH_3 PF12651.7 EMT51339.1 - 0.032 14.2 0.0 0.064 13.2 0.0 1.6 1 1 0 1 1 1 0 Ribbon-helix-helix domain RHH_5 PF07878.11 EMT51339.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Ala_racemase_N PF01168.20 EMT51340.1 - 6.5e-66 222.1 0.1 9.2e-66 221.6 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 EMT51340.1 - 4.4e-43 146.0 0.4 7.6e-43 145.3 0.1 1.6 2 0 0 2 2 2 1 Alanine racemase, C-terminal domain Wzz PF02706.15 EMT51341.1 - 0.15 12.4 0.2 1.9 8.9 0.0 2.2 2 0 0 2 2 2 0 Chain length determinant protein Spermine_synt_N PF17284.2 EMT51341.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain DUF4367 PF14285.6 EMT51342.1 - 2.7e-06 27.8 0.5 9.8e-06 26.0 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4367) ACPS PF01648.20 EMT51343.1 - 1.2e-21 76.9 0.0 1.4e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EMT51343.1 - 1.1e-06 28.7 2.4 0.0018 18.3 0.2 2.4 1 1 1 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain SASP_gamma PF04259.14 EMT51344.1 - 1.8e-08 34.8 12.6 2.4e-08 34.4 12.6 1.3 1 0 0 1 1 1 1 Small, acid-soluble spore protein, gamma-type Glutaredoxin PF00462.24 EMT51345.1 - 8.1e-07 29.2 0.0 1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EMT51345.1 - 0.02 15.3 0.1 0.033 14.6 0.1 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) ING PF12998.7 EMT51345.1 - 0.094 13.3 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding HTH_5 PF01022.20 EMT51346.1 - 1.1e-13 50.9 0.3 2.2e-13 49.8 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EMT51346.1 - 4.4e-10 39.5 0.0 6.2e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 EMT51346.1 - 2.3e-06 27.4 0.1 5.1e-06 26.3 0.0 1.7 2 1 0 2 2 2 1 MarR family Fe_dep_repress PF01325.19 EMT51346.1 - 4.4e-05 23.6 0.7 0.00051 20.2 0.7 2.2 1 1 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain BLACT_WH PF17778.1 EMT51346.1 - 9.7e-05 22.3 0.1 0.0066 16.4 0.1 2.8 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain TrmB PF01978.19 EMT51346.1 - 0.00027 20.8 0.0 0.00046 20.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EMT51346.1 - 0.0018 18.6 0.1 0.0032 17.8 0.1 1.4 1 1 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 EMT51346.1 - 0.0025 17.7 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 EMT51346.1 - 0.0071 16.5 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_27 PF13463.6 EMT51346.1 - 0.011 16.2 0.0 0.021 15.3 0.0 1.7 1 1 0 1 1 1 0 Winged helix DNA-binding domain DUF4423 PF14394.6 EMT51346.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) MarR PF01047.22 EMT51346.1 - 0.016 15.1 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 MarR family Tfb2 PF03849.14 EMT51346.1 - 0.018 14.1 0.1 0.02 13.8 0.1 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 TFIIE_alpha PF02002.17 EMT51346.1 - 0.026 14.4 0.1 0.042 13.7 0.1 1.5 1 1 0 1 1 1 0 TFIIE alpha subunit S10_plectin PF03501.15 EMT51346.1 - 0.035 14.2 0.0 0.062 13.4 0.0 1.4 1 1 0 1 1 1 0 Plectin/S10 domain HTH_IclR PF09339.10 EMT51346.1 - 0.058 13.2 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.6 EMT51346.1 - 0.06 12.9 0.9 0.14 11.8 0.1 2.1 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HxlR PF01638.17 EMT51346.1 - 0.063 13.1 0.0 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 HxlR-like helix-turn-helix PaaX PF07848.12 EMT51346.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 PaaX-like protein GntR PF00392.21 EMT51346.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_1 PF00126.27 EMT51346.1 - 0.15 12.0 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family ArsB PF02040.15 EMT51347.1 - 1.2e-183 611.3 26.5 1.4e-183 611.1 26.5 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.16 EMT51347.1 - 1.6e-23 83.3 35.4 1.6e-23 83.3 35.4 1.7 1 1 1 2 2 2 1 Citrate transporter Na_sulph_symp PF00939.19 EMT51347.1 - 0.0002 20.5 13.4 0.0002 20.5 13.4 2.5 2 1 0 2 2 2 1 Sodium:sulfate symporter transmembrane region Sec61_beta PF03911.16 EMT51347.1 - 2.1 8.5 8.7 2 8.5 0.1 3.4 3 0 0 3 3 3 0 Sec61beta family ABC_tran PF00005.27 EMT51348.1 - 6.5e-33 114.1 0.0 9.5e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT51348.1 - 1.8e-12 47.7 0.0 6.8e-06 26.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51348.1 - 3.4e-07 29.9 0.1 1.8e-05 24.3 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMT51348.1 - 4.9e-05 23.3 0.1 0.00015 21.7 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 EMT51348.1 - 6.6e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EMT51348.1 - 0.00062 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT51348.1 - 0.00069 19.9 0.1 0.0025 18.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EMT51348.1 - 0.0028 17.6 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 EMT51348.1 - 0.0034 17.6 0.0 0.0058 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMT51348.1 - 0.0045 16.7 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMT51348.1 - 0.0056 17.1 0.0 0.016 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EMT51348.1 - 0.0095 15.1 0.0 0.01 15.0 0.0 1.2 1 1 0 1 1 1 1 NB-ARC domain Adeno_IVa2 PF02456.15 EMT51348.1 - 0.0097 14.7 0.0 0.45 9.3 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_18 PF13238.6 EMT51348.1 - 0.014 15.9 0.0 0.038 14.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 EMT51348.1 - 0.018 14.6 0.1 0.046 13.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EMT51348.1 - 0.019 15.5 0.0 0.047 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EMT51348.1 - 0.024 15.1 0.0 0.29 11.6 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EMT51348.1 - 0.07 13.5 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 EMT51348.1 - 0.078 12.9 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EMT51348.1 - 0.087 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMT51348.1 - 0.096 12.4 0.1 0.23 11.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMT51348.1 - 0.1 12.2 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EMT51348.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 EMT51348.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit SbcCD_C PF13558.6 EMT51348.1 - 0.19 12.0 0.0 2.9 8.2 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit BPD_transp_1 PF00528.22 EMT51349.1 - 4.5e-26 91.7 18.1 4.5e-26 91.7 18.1 2.3 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3333 PF11812.8 EMT51349.1 - 0.19 11.9 0.2 0.19 11.9 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3333) BPD_transp_1 PF00528.22 EMT51350.1 - 1.4e-19 70.6 11.2 1.4e-19 70.6 11.2 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Sigma_reg_N PF13800.6 EMT51350.1 - 8.5 6.7 7.5 3.4 8.0 0.0 2.9 3 0 0 3 3 3 0 Sigma factor regulator N-terminal PBP_like PF12727.7 EMT51351.1 - 5.7e-40 136.5 0.0 9e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain PBP_like_2 PF12849.7 EMT51351.1 - 8.3e-38 130.7 4.0 3e-37 128.8 4.0 1.8 1 1 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.25 EMT51351.1 - 1.3e-05 25.3 11.4 2.4e-05 24.5 11.4 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein NAD_binding_2 PF03446.15 EMT51351.1 - 0.075 13.2 0.7 4.7 7.4 0.0 2.3 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF378 PF04070.12 EMT51352.1 - 9.6e-29 99.1 7.6 1.1e-28 98.9 7.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF378) Germane PF10646.9 EMT51352.1 - 0.07 13.9 0.0 0.077 13.8 0.0 1.1 1 0 0 1 1 1 0 Sporulation and spore germination Germane PF10646.9 EMT51353.1 - 5.3e-11 43.2 0.0 7.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Sporulation and spore germination RskA PF10099.9 EMT51353.1 - 0.014 15.7 1.0 0.019 15.3 1.0 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF3558 PF12079.8 EMT51353.1 - 0.042 13.8 0.4 0.059 13.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) LPAM_2 PF13627.6 EMT51353.1 - 0.18 11.7 1.4 0.28 11.1 1.4 1.3 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Amidase_3 PF01520.18 EMT51354.1 - 1.1e-54 185.2 0.1 1.8e-54 184.5 0.1 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Cu_amine_oxidN1 PF07833.11 EMT51354.1 - 6.6e-36 122.7 0.1 1.2e-30 105.8 0.1 4.2 3 2 1 5 5 5 3 Copper amine oxidase N-terminal domain AMIN PF11741.8 EMT51354.1 - 3.3e-12 46.4 0.6 7.6e-05 22.8 0.1 2.5 2 0 0 2 2 2 2 AMIN domain DUF5343 PF17278.2 EMT51354.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5343) CDC45 PF02724.14 EMT51354.1 - 0.41 8.9 14.9 0.58 8.4 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 EMT51354.1 - 1.1 8.0 5.8 1.6 7.4 5.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.15 EMT51354.1 - 1.8 7.3 8.0 2.5 6.8 8.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 EMT51354.1 - 2.8 7.3 21.7 3.9 6.8 21.7 1.1 1 0 0 1 1 1 0 SDA1 CCDC53 PF10152.9 EMT51354.1 - 3.5 8.0 6.8 6 7.3 6.8 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Nop14 PF04147.12 EMT51354.1 - 5.4 5.1 20.9 7.6 4.6 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 EMT51354.1 - 5.8 5.6 6.8 8.2 5.1 6.8 1.1 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 EMT51354.1 - 6 4.8 21.5 6.5 4.7 20.7 1.4 2 0 0 2 2 2 0 DNA polymerase phi Acetyltransf_2 PF00797.17 EMT51355.1 - 6.7e-46 157.0 0.2 7.6e-46 156.8 0.2 1.0 1 0 0 1 1 1 1 N-acetyltransferase SH2 PF00017.24 EMT51355.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 SH2 domain Peptidase_M28 PF04389.17 EMT51356.1 - 4.3e-43 147.3 0.2 1.2e-42 145.9 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 EMT51356.1 - 3.8e-18 65.3 0.1 9.5e-18 64.0 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EMT51356.1 - 0.00013 21.8 0.4 0.0003 20.5 0.4 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4910 PF16254.5 EMT51356.1 - 0.00017 20.5 0.0 0.00073 18.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4910) Peptidase_M16_M PF16187.5 EMT51356.1 - 0.12 11.6 0.1 0.55 9.5 0.0 1.9 2 0 0 2 2 2 0 Middle or third domain of peptidase_M16 DegS PF05384.11 EMT51357.1 - 0.0065 16.0 1.3 0.0097 15.4 1.3 1.2 1 0 0 1 1 1 1 Sensor protein DegS ALIX_LYPXL_bnd PF13949.6 EMT51357.1 - 0.012 14.9 0.1 0.013 14.9 0.1 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Herpes_IE2_3 PF03361.14 EMT51357.1 - 0.017 15.0 0.6 0.031 14.2 0.6 1.4 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 DUF4618 PF15397.6 EMT51357.1 - 0.018 14.5 3.6 0.024 14.1 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Spem1 PF15670.5 EMT51357.1 - 0.047 13.3 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF3562 PF12085.8 EMT51357.1 - 0.066 12.8 1.0 0.13 11.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) PRKG1_interact PF15898.5 EMT51357.1 - 0.092 13.7 2.5 0.11 13.4 1.6 1.5 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF2334 PF10096.9 EMT51357.1 - 0.13 11.8 0.1 0.31 10.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF3381 PF11861.8 EMT51357.1 - 0.36 10.6 4.3 0.49 10.2 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) SpoVIF PF14069.6 EMT51358.1 - 0.002 17.9 0.3 0.0044 16.8 0.1 1.6 1 1 0 1 1 1 1 Stage VI sporulation protein F Linker_histone PF00538.19 EMT51358.1 - 0.017 15.5 0.3 0.023 15.1 0.3 1.2 1 0 0 1 1 1 0 linker histone H1 and H5 family Acetyltransf_16 PF05301.11 EMT51358.1 - 0.03 14.1 0.1 0.03 14.1 0.1 1.0 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 DUF1002 PF06207.11 EMT51358.1 - 0.033 13.7 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) IMP2_N PF18590.1 EMT51358.1 - 0.039 14.5 0.1 0.052 14.1 0.1 1.2 1 0 0 1 1 1 0 Immune Mapped Protein 2 (IMP2) N-terminal domain DUF2087 PF09860.9 EMT51358.1 - 0.16 12.1 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) SBP_bac_5 PF00496.22 EMT51359.1 - 2.6e-93 313.0 11.2 3.4e-93 312.6 11.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF3558 PF12079.8 EMT51359.1 - 0.44 10.5 2.2 0.7 9.9 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) NPCBM PF08305.11 EMT51360.1 - 9.7e-15 55.0 0.5 1.4e-14 54.4 0.5 1.3 1 0 0 1 1 1 1 NPCBM/NEW2 domain Cu_amine_oxidN1 PF07833.11 EMT51360.1 - 0.00096 19.6 0.0 0.0022 18.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase N-terminal domain AtpR PF12966.7 EMT51360.1 - 0.095 13.2 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 N-ATPase, AtpR subunit SBP_bac_5 PF00496.22 EMT51361.1 - 1.5e-89 300.6 12.6 1.9e-89 300.3 12.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle SBP_bac_5 PF00496.22 EMT51362.1 - 1.2e-86 291.1 8.5 1.9e-86 290.4 8.5 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF3558 PF12079.8 EMT51362.1 - 4.8 7.1 6.4 7.9 6.4 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) DinB_2 PF12867.7 EMT51363.1 - 8.7e-20 71.5 0.1 1.1e-19 71.2 0.1 1.1 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 EMT51363.1 - 1.1e-14 54.8 0.1 1.2e-14 54.6 0.1 1.1 1 0 0 1 1 1 1 DinB family DUF664 PF04978.12 EMT51363.1 - 5.6e-05 23.6 0.1 0.00016 22.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF664) DUF1572 PF07609.11 EMT51363.1 - 0.0012 18.6 0.0 0.0053 16.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1572) 14-3-3 PF00244.20 EMT51363.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 14-3-3 protein SBP_bac_5 PF00496.22 EMT51364.1 - 1.5e-85 287.5 12.0 2.2e-85 286.9 12.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF3558 PF12079.8 EMT51364.1 - 5.1 7.1 5.6 8.7 6.3 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Pentapeptide PF00805.22 EMT51365.1 - 4.5e-23 80.5 3.4 6e-12 45.0 0.3 3.1 2 1 1 3 3 3 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 EMT51365.1 - 8.4e-07 29.1 0.1 0.00032 20.8 0.0 3.1 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 EMT51365.1 - 1.7e-06 28.1 0.0 2.2e-05 24.6 0.0 2.4 3 0 0 3 3 3 1 Pentapeptide repeats (9 copies) Lipoprotein_9 PF03180.14 EMT51366.1 - 8.1e-101 336.1 6.3 9.2e-101 335.9 6.3 1.0 1 0 0 1 1 1 1 NLPA lipoprotein BPD_transp_1 PF00528.22 EMT51367.1 - 1.5e-19 70.4 11.6 1.5e-19 70.4 11.6 1.4 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Comm PF15957.5 EMT51367.1 - 0.14 12.5 0.6 0.38 11.1 0.6 1.8 1 0 0 1 1 1 0 Commissureless ABC_tran PF00005.27 EMT51368.1 - 1.3e-36 126.2 0.0 2.2e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter NIL PF09383.10 EMT51368.1 - 1.4e-20 72.9 0.2 2.5e-20 72.1 0.2 1.4 1 0 0 1 1 1 1 NIL domain AAA_21 PF13304.6 EMT51368.1 - 4.8e-07 29.9 0.0 0.023 14.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51368.1 - 7.7e-05 22.2 0.4 0.00057 19.4 0.4 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMT51368.1 - 0.0004 21.0 1.2 0.00079 20.0 0.4 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMT51368.1 - 0.00055 20.2 0.4 0.0055 17.0 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT51368.1 - 0.0013 18.4 0.1 0.0026 17.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT51368.1 - 0.0025 18.2 0.2 0.0069 16.8 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMT51368.1 - 0.0051 16.7 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase WHEP-TRS PF00458.20 EMT51368.1 - 0.0073 16.4 0.3 0.022 14.9 0.3 1.8 1 0 0 1 1 1 1 WHEP-TRS domain GTP_EFTU PF00009.27 EMT51368.1 - 0.014 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.9 EMT51368.1 - 0.025 13.4 0.3 2.3 6.9 0.2 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 EMT51368.1 - 0.028 14.5 0.1 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase TniB PF05621.11 EMT51368.1 - 0.11 11.8 0.3 1.6 8.1 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 EMT51368.1 - 0.14 12.4 0.1 0.36 11.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain KIP1 PF07765.12 EMT51368.1 - 0.19 11.9 0.0 0.5 10.5 0.0 1.7 1 0 0 1 1 1 0 KIP1-like protein Spore_GerAC PF05504.11 EMT51369.1 - 4.5e-30 105.0 1.3 5.6e-30 104.7 0.1 1.7 3 0 0 3 3 3 1 Spore germination B3/ GerAC like, C-terminal Spore_permease PF03845.13 EMT51370.1 - 2.4e-76 256.6 35.3 3e-76 256.3 35.3 1.1 1 0 0 1 1 1 1 Spore germination protein GerA PF03323.13 EMT51371.1 - 2.4e-155 517.6 3.6 2.7e-155 517.4 3.6 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein SspH PF08141.12 EMT51371.1 - 0.13 12.4 0.4 0.59 10.3 0.0 2.2 2 0 0 2 2 2 0 Small acid-soluble spore protein H family LytR_cpsA_psr PF03816.14 EMT51372.1 - 7.4e-47 159.3 0.3 1e-46 158.8 0.3 1.2 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain MFS_1 PF07690.16 EMT51373.1 - 4.1e-28 98.3 67.8 1.3e-24 86.8 38.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMT51373.1 - 8.6e-06 24.6 34.6 0.0011 17.6 9.1 2.3 1 1 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 EMT51373.1 - 0.00031 20.2 29.6 0.001 18.5 17.4 2.1 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EMT51373.1 - 0.0024 16.3 17.2 0.045 12.1 15.2 2.4 1 1 1 2 2 2 2 Transmembrane secretion effector Aldo_ket_red PF00248.21 EMT51374.1 - 7.7e-29 100.8 0.0 5.6e-27 94.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family ThiC-associated PF13667.6 EMT51374.1 - 0.042 13.7 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain Disulph_isomer PF06491.11 EMT51375.1 - 1.6e-64 216.1 0.1 1.8e-64 215.9 0.1 1.0 1 0 0 1 1 1 1 Disulphide isomerase SBF PF01758.16 EMT51376.1 - 1.5e-48 165.0 14.5 3.2e-48 164.0 14.5 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 EMT51376.1 - 1.3e-24 87.1 21.8 1.6e-24 86.8 21.8 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 EMT51376.1 - 0.0026 16.2 3.4 0.0026 16.2 3.4 3.1 1 1 2 3 3 3 1 Membrane transport protein RNase_J_C PF17770.1 EMT51377.1 - 2.9e-25 89.1 0.2 5.6e-25 88.2 0.2 1.5 1 0 0 1 1 1 1 Ribonuclease J C-terminal domain Lactamase_B PF00753.27 EMT51377.1 - 4e-13 49.8 0.0 8.7e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EMT51377.1 - 1.5e-11 44.0 0.6 2.4e-10 40.2 0.1 2.6 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EMT51377.1 - 2.8e-10 40.0 0.0 5.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EMT51377.1 - 0.038 13.4 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain SCO1-SenC PF02630.14 EMT51379.1 - 1.1e-36 125.7 0.4 1.4e-36 125.3 0.4 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EMT51379.1 - 8.2e-08 32.2 0.4 2.3e-07 30.8 0.4 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMT51379.1 - 1.5e-07 31.2 0.4 4.2e-07 29.8 0.4 1.6 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EMT51379.1 - 0.00026 21.2 0.0 0.00098 19.4 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like TPR_21 PF09976.9 EMT51379.1 - 0.012 15.4 0.3 0.026 14.3 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF4307 PF14155.6 EMT51379.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Rhodanese PF00581.20 EMT51380.1 - 1.1e-13 51.6 0.0 1.3e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Cyt_bd_oxida_II PF02322.15 EMT51381.1 - 1.4e-38 133.0 34.5 1.6e-38 132.8 34.5 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II Cyt_bd_oxida_I PF01654.17 EMT51382.1 - 7.2e-126 420.2 24.6 8.1e-126 420.0 24.6 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I TraL PF07178.11 EMT51382.1 - 0.033 14.7 0.5 0.033 14.7 0.5 5.0 5 1 1 6 6 6 0 TraL protein Methyltransf_25 PF13649.6 EMT51383.1 - 6.6e-15 55.6 0.0 1.2e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT51383.1 - 9.3e-12 45.5 0.0 1.7e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT51383.1 - 1.1e-10 41.5 0.0 1.5e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT51383.1 - 6.1e-07 29.0 0.0 1.2e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMT51383.1 - 5.6e-06 27.0 0.0 1e-05 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EMT51383.1 - 0.00066 20.7 0.0 0.0015 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EMT51383.1 - 0.0011 18.6 0.0 0.0029 17.3 0.0 1.6 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F MTS PF05175.14 EMT51383.1 - 0.0017 17.9 0.0 0.0066 16.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EMT51383.1 - 0.0021 17.9 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMT51383.1 - 0.013 15.0 0.0 0.034 13.5 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 EMT51383.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 EMT51383.1 - 0.051 13.1 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 EMT51383.1 - 0.054 13.3 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EMT51383.1 - 0.083 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EMT51383.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.7 EMT51383.1 - 0.22 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cys_Met_Meta_PP PF01053.20 EMT51385.1 - 1.2e-151 504.6 0.0 1.4e-151 504.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EMT51385.1 - 1.8e-11 44.0 0.1 3.3e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EMT51385.1 - 1.9e-08 33.9 0.0 2.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMT51385.1 - 2e-08 33.6 0.0 3.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 EMT51385.1 - 0.00019 20.4 0.0 0.00028 19.9 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein SepSecS PF05889.13 EMT51385.1 - 0.0029 16.4 0.0 0.0041 15.9 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 EMT51385.1 - 0.011 15.1 0.0 0.031 13.6 0.0 1.9 1 1 0 1 1 1 0 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EMT51385.1 - 0.14 10.6 0.4 0.39 9.2 0.4 1.8 1 1 0 1 1 1 0 Methionine gamma-lyase Acetyltransf_1 PF00583.25 EMT51386.1 - 1e-15 58.0 0.0 1.4e-15 57.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT51386.1 - 1.2e-13 51.1 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT51386.1 - 2.5e-12 47.0 0.0 4.1e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT51386.1 - 1.4e-09 38.1 0.0 2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT51386.1 - 2.8e-07 30.4 0.0 5.8e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein PanZ PF12568.8 EMT51386.1 - 9.7e-05 22.1 0.1 0.00012 21.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 EMT51386.1 - 0.0003 21.0 0.0 0.0031 17.7 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT51386.1 - 0.00066 19.8 0.1 0.0013 18.8 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EMT51386.1 - 0.00078 20.1 0.0 0.00088 20.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TetR_C_27 PF17935.1 EMT51386.1 - 0.0056 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Acetyltransf_13 PF13880.6 EMT51386.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase MarR PF01047.22 EMT51387.1 - 2.3e-13 49.9 0.1 1.2e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EMT51387.1 - 6.2e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EMT51387.1 - 3e-05 24.4 0.2 7e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EMT51387.1 - 9.8e-05 21.8 0.1 0.00016 21.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EMT51387.1 - 0.00021 21.1 0.1 0.00047 20.0 0.1 1.6 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 EMT51387.1 - 0.0015 18.3 0.1 0.0046 16.7 0.0 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain DUF2250 PF10007.9 EMT51387.1 - 0.02 15.0 0.0 2.8 8.1 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Fe_dep_repress PF01325.19 EMT51387.1 - 0.032 14.4 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_34 PF13601.6 EMT51387.1 - 0.038 14.2 0.1 0.061 13.5 0.1 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.20 EMT51387.1 - 0.044 14.1 0.0 0.09 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HxlR PF01638.17 EMT51387.1 - 0.059 13.2 0.1 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 HxlR-like helix-turn-helix MFS_1 PF07690.16 EMT51388.1 - 2.6e-60 204.2 80.3 2.6e-51 174.6 44.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT51388.1 - 3.3e-09 36.1 8.7 3.3e-09 36.1 8.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EMT51388.1 - 1.1e-08 34.0 24.6 1.4e-08 33.6 24.6 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 EMT51388.1 - 2.1e-07 30.1 9.7 2.1e-07 30.1 9.7 2.5 2 1 1 3 3 3 2 MFS_1 like family Saf_2TM PF18303.1 EMT51388.1 - 1.8 8.1 10.3 0.056 13.0 2.1 2.5 2 1 0 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_M73 PF12389.8 EMT51389.1 - 3.9e-49 167.2 0.2 4.4e-49 167.0 0.2 1.0 1 0 0 1 1 1 1 Camelysin metallo-endopeptidase Peptidase_S24 PF00717.23 EMT51390.1 - 2.3e-09 37.1 0.2 4e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 Peptidase S24-like FlgD_ig PF13860.6 EMT51392.1 - 0.012 15.4 0.2 0.047 13.6 0.1 1.9 2 0 0 2 2 2 0 FlgD Ig-like domain Peptidase_M73 PF12389.8 EMT51393.1 - 2.4e-07 30.8 0.5 5.1e-06 26.5 0.1 2.3 1 1 1 2 2 2 1 Camelysin metallo-endopeptidase Beta_helix PF13229.6 EMT51393.1 - 0.00062 19.6 0.4 0.0025 17.7 0.4 1.9 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EMT51393.1 - 0.021 14.1 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Pentapeptide_3 PF13576.6 EMT51393.1 - 0.16 12.2 2.4 4.2 7.6 0.3 3.1 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Peptidase_S24 PF00717.23 EMT51394.1 - 1.1e-06 28.5 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like DUF4229 PF14012.6 EMT51394.1 - 0.56 10.3 4.4 0.85 9.8 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) HD_5 PF13487.6 EMT51395.1 - 6.6e-12 45.5 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 HD domain ATPase_gene1 PF09527.10 EMT51395.1 - 0.063 13.5 2.3 0.8 9.9 0.2 2.9 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter HD PF01966.22 EMT51395.1 - 0.09 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 HD domain SLATT_1 PF18181.1 EMT51395.1 - 0.6 10.0 5.9 0.36 10.8 0.8 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Response_reg PF00072.24 EMT51396.1 - 3.6e-25 88.3 0.6 6.7e-25 87.4 0.4 1.5 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 EMT51396.1 - 1.1e-15 57.0 0.1 2e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EMT51396.1 - 3.3e-08 33.1 0.9 9.8e-08 31.6 0.2 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT51396.1 - 6.6e-05 22.4 0.3 0.00016 21.2 0.3 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 EMT51396.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 EMT51396.1 - 0.0099 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_40 PF14493.6 EMT51396.1 - 0.015 15.7 0.2 0.06 13.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 EMT51396.1 - 0.044 13.7 0.1 0.079 12.9 0.1 1.5 1 0 0 1 1 1 0 HTH domain MgtE_N PF03448.17 EMT51396.1 - 0.096 13.3 0.5 2.3 8.9 0.2 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain HisKA_3 PF07730.13 EMT51397.1 - 1.8e-12 47.6 0.8 6.1e-12 45.9 0.8 2.0 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 EMT51397.1 - 4.8e-09 36.7 0.1 1.8e-08 34.8 0.1 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT51397.1 - 8.5e-05 22.5 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain GAF PF01590.26 EMT51397.1 - 0.011 16.4 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 GAF domain GH97_N PF14508.6 EMT51397.1 - 0.083 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal HTH_20 PF12840.7 EMT51398.1 - 3e-11 43.2 4.3 5.6e-11 42.3 2.3 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 EMT51398.1 - 1.4e-08 34.5 2.6 2.5e-08 33.6 2.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 EMT51398.1 - 0.00037 20.2 4.2 0.0006 19.6 1.9 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_10 PF04967.12 EMT51398.1 - 0.022 14.5 0.3 0.082 12.7 0.1 2.0 2 0 0 2 2 2 0 HTH DNA binding domain HTH_24 PF13412.6 EMT51398.1 - 0.037 13.6 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 EMT51398.1 - 0.13 12.7 0.6 0.38 11.2 0.3 1.9 2 0 0 2 2 2 0 Transcriptional regulator MarR_2 PF12802.7 EMT51398.1 - 0.18 11.7 3.8 0.15 12.0 0.6 2.3 2 0 0 2 2 2 0 MarR family MFS_3 PF05977.13 EMT51399.1 - 2.4e-30 105.4 29.1 3.1e-30 105.1 29.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 EMT51399.1 - 1.8e-29 102.8 49.2 1.4e-15 57.1 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT51399.1 - 8.6e-05 21.5 4.5 8.6e-05 21.5 4.5 1.9 2 0 0 2 2 2 1 MFS_1 like family AAA_3 PF07726.11 EMT51400.1 - 1.5e-61 206.0 0.0 2.5e-61 205.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EMT51400.1 - 1.9e-21 75.7 1.4 4.6e-21 74.4 0.8 2.0 2 0 0 2 2 2 1 AAA lid domain AAA_5 PF07728.14 EMT51400.1 - 1.8e-12 47.4 0.0 4.3e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMT51400.1 - 9.4e-07 28.7 0.2 0.00054 19.7 0.1 3.1 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 EMT51400.1 - 4.3e-06 26.0 0.0 6.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 EMT51400.1 - 2.3e-05 23.9 0.3 0.016 14.6 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 EMT51400.1 - 0.00018 21.9 0.0 0.00082 19.8 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMT51400.1 - 0.00024 20.9 0.0 0.0023 17.6 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EMT51400.1 - 0.0055 17.1 0.1 0.011 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF2993 PF11209.8 EMT51400.1 - 0.013 15.8 3.9 0.12 12.6 3.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2993) MCM_lid PF17855.1 EMT51400.1 - 0.046 14.1 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 MCM AAA-lid domain DUF58 PF01882.18 EMT51401.1 - 2.4e-13 50.2 0.0 6.5e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF58 DUF4131 PF13567.6 EMT51401.1 - 0.14 11.8 1.6 0.5 10.0 1.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2892 PF11127.8 EMT51401.1 - 2.8 8.1 4.6 6 7.0 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) DUF4129 PF13559.6 EMT51402.1 - 1e-09 38.5 3.4 2.8e-09 37.1 3.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) TPR_21 PF09976.9 EMT51402.1 - 0.021 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF4381 PF14316.6 EMT51402.1 - 0.062 13.5 0.1 0.062 13.5 0.1 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4381) PHO4 PF01384.20 EMT51402.1 - 1.9 7.5 7.4 2.5 7.1 7.4 1.3 1 1 0 1 1 1 0 Phosphate transporter family Multi_Drug_Res PF00893.19 EMT51403.1 - 4.2e-27 94.7 9.7 5.8e-27 94.2 9.7 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein Sugar_transport PF06800.12 EMT51403.1 - 0.00039 19.8 4.5 0.00046 19.6 4.5 1.1 1 0 0 1 1 1 1 Sugar transport protein EamA PF00892.20 EMT51403.1 - 0.00049 20.3 14.5 0.0006 20.0 14.5 1.2 1 0 0 1 1 1 1 EamA-like transporter family YwiC PF14256.6 EMT51403.1 - 0.0082 16.4 2.6 0.01 16.1 2.6 1.1 1 0 0 1 1 1 1 YwiC-like protein PUNUT PF16913.5 EMT51403.1 - 0.028 13.6 6.0 0.096 11.9 6.0 1.8 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport TMEM100 PF16311.5 EMT51403.1 - 0.059 13.0 1.5 0.096 12.3 1.5 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 DUF1011 PF06237.12 EMT51403.1 - 0.097 13.0 3.0 0.11 12.8 2.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1011) SLATT_6 PF18169.1 EMT51403.1 - 0.11 12.1 0.3 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 DUF5381 PF17353.2 EMT51403.1 - 1.9 8.2 5.4 0.74 9.5 2.9 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5381) Multi_Drug_Res PF00893.19 EMT51404.1 - 1.2e-28 99.7 7.4 1.6e-28 99.2 7.4 1.2 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 EMT51404.1 - 0.0011 19.1 12.7 0.0015 18.7 12.7 1.3 1 0 0 1 1 1 1 EamA-like transporter family Sugar_transport PF06800.12 EMT51404.1 - 0.0049 16.2 5.5 0.0055 16.1 5.5 1.0 1 0 0 1 1 1 1 Sugar transport protein TMEM234 PF10639.9 EMT51404.1 - 0.0054 16.7 1.2 0.0058 16.6 1.2 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 EmrE PF13536.6 EMT51404.1 - 0.0062 16.2 5.4 0.0062 16.2 5.4 1.1 1 0 0 1 1 1 1 Putative multidrug resistance efflux transporter UPF0060 PF02694.15 EMT51404.1 - 0.039 14.2 4.9 0.038 14.2 3.3 1.6 1 1 1 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Glucos_trans_II PF14264.6 EMT51404.1 - 0.042 13.2 6.0 0.048 13.0 6.0 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII SLATT_6 PF18169.1 EMT51404.1 - 0.75 9.4 2.8 0.85 9.2 2.7 1.3 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 TetR_C_28 PF17937.1 EMT51405.1 - 3e-22 78.9 0.0 5.6e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EMT51405.1 - 6e-14 51.6 1.0 9.3e-14 51.0 1.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family MA3 PF02847.17 EMT51405.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 MA3 domain NIF3 PF01784.18 EMT51408.1 - 0.0002 21.1 0.0 0.00026 20.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF2292 PF10055.9 EMT51409.1 - 9.8e-17 60.3 1.1 1.2e-16 60.0 1.1 1.1 1 0 0 1 1 1 1 Uncharacterized small protein (DUF2292) DUF2325 PF10087.9 EMT51410.1 - 2.5e-16 59.6 0.8 3.3e-16 59.2 0.8 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2325) Oxidored_FMN PF00724.20 EMT51412.1 - 9.1e-69 232.3 0.0 1.7e-68 231.4 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EMT51412.1 - 0.0018 17.5 0.0 0.01 14.9 0.0 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EMT51412.1 - 0.0088 15.5 0.0 0.14 11.6 0.0 2.7 3 1 1 4 4 4 1 Histidine biosynthesis protein NMO PF03060.15 EMT51412.1 - 0.11 11.9 0.5 0.17 11.3 0.5 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase LPAM_1 PF08139.12 EMT51413.1 - 0.00061 20.1 0.4 0.0013 19.1 0.4 1.6 1 0 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site Citrate_synt PF00285.21 EMT51414.1 - 1.6e-119 399.2 0.0 1.8e-119 399.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF418 PF04235.12 EMT51415.1 - 2.7e-31 108.7 9.3 2.7e-31 108.7 9.3 2.9 1 1 3 4 4 4 2 Protein of unknown function (DUF418) Acyl_transf_3 PF01757.22 EMT51415.1 - 0.031 13.4 36.6 0.44 9.5 22.6 2.9 1 1 1 2 2 2 0 Acyltransferase family FA_desaturase PF00487.24 EMT51415.1 - 9.4 6.0 20.2 0.15 11.9 7.0 2.2 2 0 0 2 2 2 0 Fatty acid desaturase LysR_substrate PF03466.20 EMT51416.1 - 2.5e-33 115.2 0.3 3.4e-33 114.8 0.3 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT51416.1 - 6.1e-19 67.7 0.4 1.4e-18 66.6 0.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 EMT51416.1 - 0.00069 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_30 PF13556.6 EMT51416.1 - 0.0073 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Lipoprotein_17 PF04200.12 EMT51418.1 - 1.7 9.1 7.8 6.8 7.1 2.2 3.8 1 1 2 3 3 3 0 Lipoprotein associated domain Peptidase_S8 PF00082.22 EMT51419.1 - 1.2e-58 198.8 1.9 2e-58 198.0 1.9 1.4 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 EMT51419.1 - 1.2e-13 50.8 0.5 1.2e-13 50.8 0.5 2.4 2 0 0 2 2 2 1 PA domain fn3_5 PF06280.12 EMT51419.1 - 1.3e-10 41.9 0.4 1.3e-10 41.9 0.4 3.4 3 1 0 3 3 3 1 Fn3-like domain Inhibitor_I9 PF05922.16 EMT51419.1 - 6.3e-07 30.0 0.2 2.2e-06 28.2 0.2 2.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 fn3_6 PF17766.1 EMT51419.1 - 7.9e-05 22.8 0.0 0.00042 20.4 0.0 2.3 1 0 0 1 1 1 1 Fibronectin type-III domain DUF1616 PF07760.11 EMT51419.1 - 0.037 13.4 0.6 0.066 12.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF916 PF06030.12 EMT51419.1 - 0.11 12.6 2.6 4.8 7.3 0.7 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF916) FixG_C PF11614.8 EMT51419.1 - 0.26 11.5 3.7 7.6 6.8 0.1 3.1 3 0 0 3 3 3 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Epimerase PF01370.21 EMT51420.1 - 8.5e-16 58.1 0.2 3.1e-14 53.0 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMT51420.1 - 2.7e-06 26.6 0.0 0.011 14.7 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMT51420.1 - 5.3e-05 22.8 0.0 0.2 11.0 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMT51420.1 - 0.00013 21.9 0.0 0.00031 20.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EMT51420.1 - 0.018 14.2 0.0 0.054 12.6 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 EMT51420.1 - 0.043 13.4 0.0 0.32 10.5 0.1 2.0 2 0 0 2 2 2 0 NmrA-like family NAD_binding_2 PF03446.15 EMT51420.1 - 0.077 13.2 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 EMT51420.1 - 0.24 10.9 0.1 0.48 9.8 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase CLP_protease PF00574.23 EMT51421.1 - 5.5e-86 287.1 0.0 6.3e-86 286.9 0.0 1.0 1 0 0 1 1 1 1 Clp protease Pro_Al_protease PF02983.14 EMT51422.1 - 0.15 12.2 1.3 0.17 11.9 0.3 1.6 2 0 0 2 2 2 0 Alpha-lytic protease prodomain HTH_20 PF12840.7 EMT51423.1 - 1.1e-12 47.8 0.2 2.1e-12 46.9 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.10 EMT51423.1 - 0.00047 20.1 0.1 0.001 19.0 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain MarR_2 PF12802.7 EMT51423.1 - 0.0029 17.5 0.4 0.014 15.2 0.2 2.3 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.20 EMT51423.1 - 0.0089 15.9 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 EMT51423.1 - 0.012 15.4 0.2 0.1 12.5 0.1 2.3 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.16 EMT51423.1 - 0.02 14.6 0.1 0.046 13.5 0.1 1.6 1 0 0 1 1 1 0 LexA DNA binding domain HTH_24 PF13412.6 EMT51423.1 - 0.054 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF429 PF04250.13 EMT51423.1 - 0.14 11.9 0.5 0.35 10.6 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF429) Na_H_Exchanger PF00999.21 EMT51426.1 - 4.6e-80 269.2 47.7 5.3e-80 269.0 47.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ribosomal_L33 PF00471.20 EMT51427.1 - 2.6e-24 85.4 5.1 2.8e-24 85.3 5.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 cobW PF02492.19 EMT51428.1 - 2.3e-58 196.7 0.3 3e-58 196.3 0.3 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EMT51428.1 - 2.7e-30 104.2 0.3 8.7e-30 102.5 0.3 1.9 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EMT51428.1 - 8.2e-05 22.6 0.1 0.068 13.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 EMT51428.1 - 0.00094 18.2 0.3 0.043 12.8 0.2 2.7 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EMT51428.1 - 0.0078 16.6 0.7 0.024 15.0 0.2 2.2 2 1 0 2 2 2 1 AAA ATPase domain MobB PF03205.14 EMT51428.1 - 0.024 14.5 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 EMT51428.1 - 0.026 14.4 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 EMT51428.1 - 0.032 14.2 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EMT51428.1 - 0.036 13.1 0.1 0.067 12.2 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein GTP_EFTU PF00009.27 EMT51428.1 - 0.057 13.0 0.0 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMT51428.1 - 0.091 12.9 0.2 0.45 10.6 0.2 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EMT51428.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMT51428.1 - 0.17 12.4 0.3 1.1 9.8 0.1 2.2 1 1 0 2 2 2 0 AAA domain Nitr_red_bet_C PF14711.6 EMT51428.1 - 0.19 11.5 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal VCBS PF13517.6 EMT51430.1 - 0.00044 20.8 0.4 0.13 12.8 0.0 4.2 3 1 1 5 5 5 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SurA_N_3 PF13624.6 EMT51430.1 - 0.078 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain FG-GAP PF01839.23 EMT51430.1 - 0.32 11.2 1.8 1.6 8.9 0.5 2.8 3 0 0 3 3 3 0 FG-GAP repeat Response_reg PF00072.24 EMT51431.1 - 3.9e-26 91.4 0.0 7.6e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT51431.1 - 1.6e-25 89.0 0.0 3.4e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 EMT51432.1 - 6.6e-28 97.5 0.1 2.1e-27 95.9 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT51432.1 - 3.1e-15 55.9 0.1 9.8e-15 54.4 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EMT51432.1 - 1.3e-13 51.1 0.0 2.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 HAMP domain HATPase_c_5 PF14501.6 EMT51432.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 EMT51432.1 - 0.00024 21.1 0.0 0.00075 19.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EMT51432.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nitroreductase PF00881.24 EMT51433.1 - 1.5e-34 119.5 0.2 1.9e-34 119.2 0.2 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EMT51433.1 - 1.8e-10 40.7 0.0 0.0039 16.8 0.0 3.5 2 2 2 4 4 4 3 Putative TM nitroreductase adh_short_C2 PF13561.6 EMT51434.1 - 9.7e-71 238.0 0.0 1.1e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT51434.1 - 7.9e-56 188.6 0.0 9.2e-56 188.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT51434.1 - 2e-08 34.4 0.3 2.9e-08 33.9 0.3 1.2 1 0 0 1 1 1 1 KR domain DFP PF04127.15 EMT51434.1 - 0.027 14.3 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.21 EMT51434.1 - 0.045 13.2 0.1 0.1 12.1 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EMT51434.1 - 0.077 12.9 0.5 0.12 12.3 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMT51434.1 - 0.4 10.7 1.0 0.85 9.7 1.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase COX1 PF00115.20 EMT51435.1 - 4.9e-89 299.1 72.8 4.9e-89 299.1 72.8 2.0 1 1 1 2 2 2 2 Cytochrome C and Quinol oxidase polypeptide I BatA PF07584.11 EMT51435.1 - 1.2 9.5 6.2 0.93 9.9 0.2 3.6 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal COX2 PF00116.20 EMT51436.1 - 9.4e-14 51.3 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.6 EMT51436.1 - 2e-05 24.7 0.0 2.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain CoxIIa PF08113.11 EMT51437.1 - 0.00064 19.5 5.2 0.00077 19.2 5.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IIa family CrgA PF06781.12 EMT51437.1 - 0.04 14.0 0.0 0.042 13.9 0.0 1.1 1 0 0 1 1 1 0 Cell division protein CrgA Response_reg PF00072.24 EMT51438.1 - 1.1e-25 89.9 0.3 2.2e-25 89.0 0.1 1.6 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 EMT51438.1 - 1.6e-21 75.6 0.4 3.4e-21 74.5 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EMT51438.1 - 1.1e-09 37.8 0.2 2.2e-09 36.8 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT51438.1 - 0.00013 21.4 0.3 0.00031 20.2 0.3 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT51438.1 - 0.00014 21.8 0.2 0.0016 18.4 0.1 2.0 1 1 1 2 2 2 1 ECF sigma factor HTH_38 PF13936.6 EMT51438.1 - 0.0055 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EMT51438.1 - 0.0086 15.8 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_40 PF14493.6 EMT51438.1 - 0.013 16.0 0.7 0.036 14.5 0.3 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 EMT51438.1 - 0.015 15.4 0.4 0.084 13.0 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 EMT51438.1 - 0.03 14.3 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Terminase_5 PF06056.12 EMT51438.1 - 0.036 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_11 PF08279.12 EMT51438.1 - 0.07 13.1 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 HTH domain HisKA_3 PF07730.13 EMT51439.1 - 4.9e-15 55.8 0.6 4.9e-15 55.8 0.6 2.0 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 EMT51439.1 - 3.5e-13 50.0 0.4 8.5e-13 48.8 0.1 1.9 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 EMT51439.1 - 4.2e-11 42.9 0.3 8.5e-10 38.6 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EMT51439.1 - 1.3e-10 41.4 0.0 3.7e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EMT51439.1 - 8.1e-09 35.7 0.2 6.9e-08 32.7 0.0 2.6 3 1 0 3 3 3 1 PAS fold PAS_8 PF13188.7 EMT51439.1 - 5.2e-08 32.7 0.0 1.3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 EMT51439.1 - 1.2e-05 25.2 0.0 2.9e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_3 PF08447.12 EMT51439.1 - 0.00042 20.5 0.0 0.00092 19.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold DUF2616 PF11077.8 EMT51439.1 - 0.075 12.7 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) HATPase_c_3 PF13589.6 EMT51439.1 - 0.08 12.8 0.2 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_7 PF12860.7 EMT51439.1 - 0.23 11.7 3.4 0.39 10.9 0.1 2.9 2 1 2 4 4 4 0 PAS fold OmpH PF03938.14 EMT51439.1 - 8.1 6.8 10.0 7.2 7.0 3.8 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) MFS_1 PF07690.16 EMT51440.1 - 4.6e-40 137.6 56.8 6.6e-26 91.1 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT51440.1 - 3e-09 36.3 25.0 2.6e-07 29.9 10.9 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 EMT51440.1 - 1.3e-08 34.6 31.3 1.8e-08 34.1 31.3 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EMT51440.1 - 0.043 12.1 0.1 0.043 12.1 0.1 2.5 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Acetyltransf_1 PF00583.25 EMT51441.1 - 9.1e-15 54.9 0.0 1.1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT51441.1 - 4.9e-14 52.4 0.0 6.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT51441.1 - 2.1e-13 50.7 0.0 2.6e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT51441.1 - 3e-09 37.2 0.0 4.4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT51441.1 - 1.3e-08 34.7 0.1 1.8e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EMT51441.1 - 2.5e-07 31.5 0.0 3.6e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT51441.1 - 2.5e-05 24.3 0.0 4.7e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT51441.1 - 0.00038 20.5 0.1 0.00071 19.7 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EMT51441.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.3 1 1 0 1 1 1 1 Putative acetyl-transferase GNAT_acetyltran PF12746.7 EMT51441.1 - 0.0033 17.0 0.0 0.0075 15.9 0.0 1.5 1 1 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_8 PF13523.6 EMT51441.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EMT51441.1 - 0.096 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PTAC PF06130.12 EMT51441.1 - 0.17 12.1 0.0 7.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Phosphate propanoyltransferase Cu_amine_oxidN1 PF07833.11 EMT51442.1 - 2.7e-16 59.8 0.6 8.8e-16 58.2 0.2 2.1 2 0 0 2 2 2 1 Copper amine oxidase N-terminal domain DUF3221 PF11518.8 EMT51442.1 - 0.01 16.2 0.1 0.11 12.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3221) FeoA PF04023.14 EMT51442.1 - 0.017 15.4 0.3 11 6.3 0.0 2.9 3 0 0 3 3 3 0 FeoA domain NusG_II PF07009.11 EMT51442.1 - 0.18 12.0 2.1 2.5 8.3 0.0 3.4 2 1 2 4 4 4 0 NusG domain II Spore_YunB PF09560.10 EMT51443.1 - 2.5e-29 101.1 2.8 4.7e-29 100.3 2.8 1.5 1 0 0 1 1 1 1 Sporulation protein YunB (Spo_YunB) KH_5 PF13184.6 EMT51443.1 - 0.051 13.7 0.2 0.099 12.7 0.2 1.5 1 0 0 1 1 1 0 NusA-like KH domain GIDA PF01134.22 EMT51443.1 - 0.063 12.3 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A E1-E2_ATPase PF00122.20 EMT51444.1 - 1.4e-54 184.4 2.0 1.4e-54 184.4 2.0 3.3 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMT51444.1 - 1.4e-51 174.8 1.8 1.4e-51 174.8 1.8 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EMT51444.1 - 4.9e-25 89.1 1.2 3.1e-24 86.4 1.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMT51444.1 - 4.9e-20 71.4 0.0 1.1e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EMT51444.1 - 1.3e-18 66.5 0.1 3.2e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 EMT51444.1 - 8.8e-05 23.0 0.1 0.00024 21.6 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMT51444.1 - 0.00013 21.8 0.8 0.0013 18.5 0.6 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PGM1_C PF18105.1 EMT51444.1 - 0.018 14.5 2.1 0.35 10.4 0.1 3.7 4 0 0 4 4 4 0 PGM1 C-terminal domain HTH_AsnC-type PF13404.6 EMT51444.1 - 0.14 12.0 3.9 59 3.6 0.0 4.5 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain Mntp PF02659.15 EMT51445.1 - 1.1e-17 64.2 14.8 3.6e-11 43.0 0.6 2.1 2 0 0 2 2 2 2 Putative manganese efflux pump Spo0M PF07070.11 EMT51446.1 - 5e-44 150.4 0.1 6.8e-44 149.9 0.1 1.2 1 0 0 1 1 1 1 SpoOM protein Rgp1 PF08737.10 EMT51446.1 - 0.00019 20.8 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.22 EMT51446.1 - 0.018 15.5 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain DUF2076 PF09849.9 EMT51446.1 - 0.055 13.5 0.9 0.077 13.0 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cadherin_C PF01049.17 EMT51446.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic region KdpC PF02669.15 EMT51448.1 - 4.1e-75 251.6 0.0 4.6e-75 251.5 0.0 1.0 1 0 0 1 1 1 1 K+-transporting ATPase, c chain E1-E2_ATPase PF00122.20 EMT51449.1 - 6.2e-37 126.9 4.7 6.2e-37 126.9 4.7 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMT51449.1 - 1.3e-35 123.6 1.3 2.6e-35 122.6 1.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMT51449.1 - 2.5e-07 30.7 0.8 0.00033 20.5 0.6 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMT51449.1 - 0.00013 22.5 0.0 0.001 19.5 0.0 2.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase KdpA PF03814.15 EMT51450.1 - 3.8e-241 801.0 36.0 4.4e-241 800.8 36.0 1.0 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit DUF2818 PF10993.8 EMT51450.1 - 0.079 13.5 0.1 0.079 13.5 0.1 3.7 4 1 2 6 6 6 0 Protein of unknown function (DUF2818) DUF2768 PF10966.8 EMT51450.1 - 0.11 12.9 0.2 0.11 12.9 0.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2768) Smim3 PF17307.2 EMT51450.1 - 1.5 8.4 4.6 3.1 7.4 1.0 2.8 2 0 0 2 2 2 0 Small integral membrane protein 3 DUF2294 PF10057.9 EMT51451.1 - 5.9e-37 126.2 1.5 6.8e-37 126.0 1.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2294) CDC37_C PF08564.10 EMT51451.1 - 0.043 14.0 0.1 0.11 12.6 0.1 1.8 1 1 0 1 1 1 0 Cdc37 C terminal domain S1 PF00575.23 EMT51451.1 - 0.047 14.0 0.4 0.76 10.2 0.4 2.4 1 1 0 1 1 1 0 S1 RNA binding domain DUF3267 PF11667.8 EMT51452.1 - 7.6e-23 80.9 3.9 7.6e-23 80.9 3.9 1.9 1 1 1 2 2 2 1 Putative zincin peptidase HMA PF00403.26 EMT51453.1 - 7.4e-14 51.9 2.0 1.1e-13 51.3 2.0 1.3 1 1 0 1 1 1 1 Heavy-metal-associated domain TusA PF01206.17 EMT51453.1 - 0.0072 16.1 0.0 0.0086 15.9 0.0 1.1 1 0 0 1 1 1 1 Sulfurtransferase TusA Tox-PL-2 PF15643.6 EMT51453.1 - 0.0084 16.2 0.0 0.0094 16.1 0.0 1.2 1 0 0 1 1 1 1 Papain fold toxin 2 DUF211 PF02680.14 EMT51453.1 - 0.022 14.9 0.4 2.3 8.4 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 Thiamine_BP PF01910.17 EMT51453.1 - 0.063 13.2 0.2 0.064 13.2 0.2 1.0 1 0 0 1 1 1 0 Thiamine-binding protein TubC_N PF18563.1 EMT51453.1 - 0.11 12.5 0.0 0.45 10.5 0.0 1.9 3 0 0 3 3 3 0 TubC N-terminal docking domain E1-E2_ATPase PF00122.20 EMT51454.1 - 6.1e-59 198.6 3.8 9e-59 198.0 2.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMT51454.1 - 2.8e-49 168.3 6.9 6.3e-49 167.1 6.9 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EMT51454.1 - 1.6e-37 127.7 0.9 4.6e-18 65.4 0.2 2.8 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EMT51454.1 - 7.6e-08 32.4 3.8 0.00033 20.5 1.1 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMT51454.1 - 3.3e-05 24.4 0.1 0.00015 22.2 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase YscJ_FliF PF01514.17 EMT51454.1 - 0.00016 21.4 0.1 0.094 12.4 0.0 2.9 2 0 0 2 2 2 2 Secretory protein of YscJ/FliF family SAM_Exu PF18609.1 EMT51454.1 - 0.022 14.9 0.2 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 Exuperantia SAM-like domain PCP_red PF08369.10 EMT51454.1 - 0.14 12.4 0.3 0.46 10.7 0.3 1.9 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Fer4_11 PF13247.6 EMT51454.1 - 0.15 12.2 1.0 4.4 7.5 0.3 2.9 1 1 2 3 3 3 0 4Fe-4S dicluster domain Tox-PL-2 PF15643.6 EMT51454.1 - 0.45 10.7 1.5 21 5.3 0.1 2.5 1 1 1 2 2 2 0 Papain fold toxin 2 DUF4128 PF13554.6 EMT51454.1 - 2.8 8.0 4.4 9.6 6.3 0.0 3.2 4 0 0 4 4 4 0 Bacteriophage related domain of unknown function GGDEF PF00990.21 EMT51455.1 - 6.4e-46 156.0 0.0 9.6e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain 5TM-5TMR_LYT PF07694.12 EMT51455.1 - 4.1e-12 45.9 19.5 6.4e-12 45.3 19.5 1.3 1 0 0 1 1 1 1 5TMR of 5TMR-LYT PAS_8 PF13188.7 EMT51455.1 - 5.6e-10 39.0 0.0 2.8e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EMT51455.1 - 1e-09 38.4 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EMT51455.1 - 6.7e-08 32.7 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EMT51455.1 - 1.5e-05 25.2 0.3 3.8e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 PAS fold PAS_7 PF12860.7 EMT51455.1 - 0.0012 19.0 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold GGDEF_2 PF17853.1 EMT51455.1 - 0.037 14.3 0.1 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 GGDEF-like domain PAS_3 PF08447.12 EMT51455.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 PAS fold Indigoidine_A PF04227.12 EMT51456.1 - 3.9e-136 453.1 1.1 4.4e-136 453.0 1.1 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EMT51457.1 - 8.4e-66 222.3 0.0 1.1e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HTH_24 PF13412.6 EMT51457.1 - 6.7e-11 41.6 0.0 1.4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Phos_pyr_kin PF08543.12 EMT51457.1 - 8.5e-09 35.1 0.0 1.7e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HTH_11 PF08279.12 EMT51457.1 - 3.8e-08 33.1 0.0 8.8e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 EMT51457.1 - 1.4e-05 24.9 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EMT51457.1 - 1.6e-05 24.7 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 EMT51457.1 - 0.00045 20.0 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 EMT51457.1 - 0.0008 19.3 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_3 PF01381.22 EMT51457.1 - 0.0012 18.9 0.7 0.0024 17.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_AsnC-type PF13404.6 EMT51457.1 - 0.0015 18.3 0.0 0.004 17.0 0.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.16 EMT51457.1 - 0.0024 17.4 0.0 0.0056 16.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 FaeA PF04703.12 EMT51457.1 - 0.0062 16.9 0.1 0.017 15.5 0.1 1.7 1 0 0 1 1 1 1 FaeA-like protein FeoC PF09012.10 EMT51457.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_36 PF13730.6 EMT51457.1 - 0.024 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_WhiA PF02650.14 EMT51457.1 - 0.039 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 WhiA C-terminal HTH domain DDRGK PF09756.9 EMT51457.1 - 0.045 13.4 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 DDRGK domain Mga PF05043.13 EMT51457.1 - 0.054 14.1 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 Mga helix-turn-helix domain Phage_CI_repr PF07022.13 EMT51457.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Fe_dep_repress PF01325.19 EMT51457.1 - 0.11 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_5 PF01022.20 EMT51457.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_19 PF12844.7 EMT51457.1 - 0.13 12.3 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain EamA PF00892.20 EMT51458.1 - 1e-36 126.2 38.0 2.7e-18 66.5 13.6 2.0 2 0 0 2 2 2 2 EamA-like transporter family 7TM_GPCR_Srz PF10325.9 EMT51458.1 - 0.049 12.9 0.5 0.049 12.9 0.5 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz DHHC PF01529.20 EMT51458.1 - 7.1 6.7 7.3 0.49 10.5 0.5 2.4 2 1 0 2 2 2 0 DHHC palmitoyltransferase FCD PF07729.12 EMT51459.1 - 2.5e-23 82.9 6.4 2.6e-23 82.8 5.6 1.5 1 1 0 1 1 1 1 FCD domain GntR PF00392.21 EMT51459.1 - 3.5e-16 58.6 0.8 5.9e-16 57.9 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 EMT51459.1 - 0.0003 20.6 0.0 0.00074 19.4 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EMT51459.1 - 0.0012 18.3 0.0 0.0031 17.0 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EMT51459.1 - 0.0053 16.6 0.0 0.05 13.4 0.0 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 EMT51459.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_IclR PF09339.10 EMT51459.1 - 0.024 14.4 0.0 0.089 12.6 0.0 2.0 1 0 0 1 1 1 0 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 EMT51459.1 - 0.041 14.1 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 EMT51459.1 - 0.077 13.0 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 EMT51459.1 - 0.1 13.0 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_CodY PF08222.11 EMT51459.1 - 0.14 11.8 0.0 0.62 9.7 0.0 2.1 2 0 0 2 2 2 0 CodY helix-turn-helix domain HrcA_DNA-bdg PF03444.15 EMT51459.1 - 0.15 11.7 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Acetyltransf_10 PF13673.7 EMT51460.1 - 4.7e-15 55.7 0.1 8e-15 54.9 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT51460.1 - 2e-13 50.6 0.0 2.5e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT51460.1 - 1.3e-12 47.9 0.0 2.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT51460.1 - 3.8e-06 27.1 0.0 4.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT51460.1 - 7e-05 22.7 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EMT51460.1 - 0.00041 21.0 0.0 0.00049 20.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EMT51460.1 - 0.00071 19.3 0.0 0.00088 19.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 EMT51460.1 - 0.0095 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 EMT51460.1 - 0.026 14.2 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT51460.1 - 0.097 12.7 0.0 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EMT51460.1 - 0.18 11.2 0.0 0.65 9.4 0.0 1.8 1 1 0 1 1 1 0 Putative acetyl-transferase MarR PF01047.22 EMT51462.1 - 1e-16 60.6 0.0 2.4e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EMT51462.1 - 5.1e-12 45.5 0.0 1.6e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 EMT51462.1 - 6e-09 36.3 0.0 2.7e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EMT51462.1 - 6.5e-06 25.6 0.0 2.6e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 EMT51462.1 - 6.9e-05 23.0 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 EMT51462.1 - 0.0059 16.5 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 EMT51462.1 - 0.036 14.1 0.0 0.33 11.0 0.0 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain PadR PF03551.14 EMT51462.1 - 0.048 13.6 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family B-block_TFIIIC PF04182.12 EMT51462.1 - 0.064 13.4 0.1 0.12 12.5 0.1 1.6 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC Flavodoxin_2 PF02525.17 EMT51463.1 - 1.7e-42 145.4 0.1 2e-42 145.2 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EMT51463.1 - 6.4e-06 26.0 0.0 7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 EMT51463.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin DoxX PF07681.12 EMT51464.1 - 3.8e-20 72.3 12.6 3.8e-20 72.3 12.6 1.7 2 0 0 2 2 2 1 DoxX Pirin PF02678.16 EMT51465.1 - 1.6e-18 66.6 0.6 3.4e-18 65.6 0.6 1.6 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EMT51465.1 - 0.0077 15.9 0.4 3.8 7.3 0.2 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding_2 PF14525.6 EMT51465.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 AraC-binding-like domain Pirin_C PF05726.13 EMT51465.1 - 0.069 13.5 0.0 0.35 11.3 0.0 2.0 2 0 0 2 2 2 0 Pirin C-terminal cupin domain Cyt_bd_oxida_I PF01654.17 EMT51466.1 - 2.7e-122 408.4 21.4 3.1e-122 408.2 21.4 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I Cyt_bd_oxida_II PF02322.15 EMT51467.1 - 1.6e-34 119.7 38.1 1.9e-34 119.4 38.1 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II AcetylCoA_hyd_C PF13336.6 EMT51468.1 - 1.3e-45 155.1 0.0 2.9e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 EMT51468.1 - 1.2e-26 93.9 0.1 5.6e-26 91.7 0.1 2.0 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain CitF PF04223.12 EMT51468.1 - 3.1e-07 29.7 2.7 1.1e-06 27.8 1.2 2.4 2 2 1 3 3 3 1 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.23 EMT51468.1 - 0.0013 18.2 0.7 0.0088 15.5 0.0 2.2 2 1 1 3 3 3 1 Coenzyme A transferase Multi_Drug_Res PF00893.19 EMT51470.1 - 2.7e-20 72.8 4.7 3.5e-20 72.5 4.7 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein TetR_N PF00440.23 EMT51470.1 - 0.0001 22.0 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_40 PF14493.6 EMT51470.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain LytTR PF04397.15 EMT51471.1 - 9.7e-28 96.3 0.0 1.3e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 LytTr DNA-binding domain PIG-X PF08320.12 EMT51471.1 - 0.044 13.7 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 PIG-X / PBN1 Na_Ala_symp PF01235.17 EMT51472.1 - 1.3e-164 548.2 28.1 1.6e-164 547.9 28.1 1.0 1 0 0 1 1 1 1 Sodium:alanine symporter family HCO3_cotransp PF00955.21 EMT51472.1 - 0.0063 15.4 0.5 0.017 14.0 0.5 1.6 1 0 0 1 1 1 1 HCO3- transporter family DUF4519 PF15012.6 EMT51472.1 - 8.7 6.6 5.5 62 3.9 2.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Sulfate_transp PF00916.20 EMT51474.1 - 1.1e-63 215.2 33.0 2.5e-34 118.7 8.1 2.3 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 EMT51474.1 - 1.4e-09 37.6 0.0 2.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EMT51474.1 - 1.1e-05 25.8 3.7 1.1e-05 25.8 3.7 4.1 3 1 1 4 4 4 3 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EMT51474.1 - 0.0002 21.7 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain SafA PF17073.5 EMT51474.1 - 0.26 11.3 2.2 0.34 10.9 0.1 2.4 2 0 0 2 2 2 0 Two-component-system connector protein MFS_3 PF05977.13 EMT51475.1 - 4e-30 104.7 22.6 5.2e-30 104.3 22.6 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 EMT51475.1 - 9.3e-30 103.7 77.0 2e-24 86.2 38.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Hemerythrin PF01814.23 EMT51476.1 - 7e-15 55.8 5.7 7.6e-15 55.7 5.1 1.4 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain TetR_C_15 PF17918.1 EMT51476.1 - 0.0051 17.5 0.5 0.021 15.6 0.1 2.0 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain LPD39 PF18858.1 EMT51476.1 - 0.05 13.7 0.1 0.066 13.3 0.1 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 GlutR_dimer PF00745.20 EMT51476.1 - 0.073 13.5 3.1 0.28 11.7 0.1 2.5 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF1627 PF07789.12 EMT51476.1 - 0.14 11.8 0.1 0.22 11.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1627) YgaB PF14182.6 EMT51476.1 - 0.44 11.0 8.9 0.97 9.9 4.0 2.7 1 1 0 2 2 2 0 YgaB-like protein cNMP_binding PF00027.29 EMT51477.1 - 1.3e-18 66.9 0.0 2.1e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 EMT51477.1 - 2e-17 62.9 0.1 3.7e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 EMT51477.1 - 2.9e-11 42.8 0.0 5.5e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family HTH_24 PF13412.6 EMT51477.1 - 0.00024 20.6 0.0 0.00052 19.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HKR_ArcB_TM PF18415.1 EMT51478.1 - 0.029 15.1 1.9 0.035 14.9 1.9 1.1 1 0 0 1 1 1 0 Histidine kinase receptor ArcB trans-membrane domain Rieske PF00355.26 EMT51479.1 - 2.3e-12 46.7 0.1 3.6e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fer4_11 PF13247.6 EMT51480.1 - 7.6e-22 77.3 11.5 7.6e-22 77.3 11.5 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EMT51480.1 - 2.6e-10 40.7 31.9 0.00021 21.8 11.2 3.8 2 2 2 4 4 4 4 4Fe-4S dicluster domain Fer4_9 PF13187.6 EMT51480.1 - 2e-08 34.3 30.7 1.9e-05 24.8 11.5 3.2 1 1 4 5 5 5 5 4Fe-4S dicluster domain Fer4_21 PF14697.6 EMT51480.1 - 2.4e-08 34.0 27.9 5.5e-05 23.2 11.0 3.7 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMT51480.1 - 2.5e-08 33.9 32.9 5.4e-06 26.4 11.9 3.4 1 1 3 4 4 4 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 EMT51480.1 - 1.5e-07 31.1 35.3 0.00099 19.1 2.0 4.6 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4 PF00037.27 EMT51480.1 - 2.2e-07 30.4 40.2 0.00023 20.8 5.2 5.4 6 0 0 6 6 6 4 4Fe-4S binding domain Fer4_6 PF12837.7 EMT51480.1 - 5.8e-07 29.3 42.4 0.0032 17.5 4.5 5.0 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_4 PF12800.7 EMT51480.1 - 2.3e-05 24.5 38.8 0.006 17.0 4.1 5.1 5 0 0 5 5 5 3 4Fe-4S binding domain Fer4_17 PF13534.6 EMT51480.1 - 6.2e-05 23.5 30.0 0.19 12.3 11.5 3.8 1 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 EMT51480.1 - 9.5e-05 23.1 3.6 9.5e-05 23.1 3.6 3.0 3 0 0 3 3 3 1 4Fe-4S single cluster domain Fer4_16 PF13484.6 EMT51480.1 - 0.0021 18.9 33.8 0.85 10.6 3.7 4.8 3 1 1 5 5 5 3 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 EMT51480.1 - 0.0026 18.2 30.6 0.053 14.0 2.5 3.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 EMT51480.1 - 0.012 16.4 42.9 0.082 13.9 3.6 4.4 4 0 0 4 4 4 0 4Fe-4S binding domain ETF_QO PF05187.13 EMT51480.1 - 2.7 8.2 14.6 5.8 7.1 5.0 3.2 1 1 1 3 3 3 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 EMT51480.1 - 4.7 8.1 25.0 1.8 9.4 2.7 4.0 3 1 0 4 4 4 0 4Fe-4S dicluster domain Molybdopterin PF00384.22 EMT51481.1 - 6.3e-81 272.5 0.0 7.6e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EMT51481.1 - 1.7e-30 105.3 0.0 3.1e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 EMT51481.1 - 1.1e-13 50.9 3.5 2.1e-13 50.0 3.5 1.5 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Nitrate_red_gam PF02665.14 EMT51482.1 - 0.00034 20.2 13.4 0.0024 17.4 0.9 2.8 2 1 1 3 3 3 2 Nitrate reductase gamma subunit MFS_1 PF07690.16 EMT51483.1 - 1.3e-46 159.2 66.9 8.6e-39 133.4 41.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PAS_9 PF13426.7 EMT51483.1 - 3.9e-17 62.4 0.0 6e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EMT51483.1 - 3.8e-16 59.1 0.0 6.1e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EMT51483.1 - 1.5e-07 31.6 0.0 2.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EMT51483.1 - 4e-07 29.9 0.0 9.2e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EMT51483.1 - 4.8e-05 23.6 0.1 8.1e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 PAS fold OATP PF03137.20 EMT51483.1 - 0.00089 17.7 1.1 0.00089 17.7 1.1 2.6 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family PAS_12 PF18095.1 EMT51483.1 - 0.013 15.1 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain HATPase_c PF02518.26 EMT51484.1 - 2.9e-30 105.0 0.1 5.4e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT51484.1 - 1.1e-18 67.0 1.7 2e-18 66.2 0.2 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EMT51484.1 - 9.2e-15 54.8 0.1 2.7e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 HAMP domain HATPase_c_5 PF14501.6 EMT51484.1 - 3.5e-05 23.6 0.0 8.8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 EMT51484.1 - 0.0009 19.1 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT51484.1 - 0.00093 19.2 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain sCache_like PF16736.5 EMT51484.1 - 0.0046 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Single Cache-like DUF4635 PF15466.6 EMT51484.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) bPH_5 PF10882.8 EMT51484.1 - 0.022 14.8 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial PH domain SIN1 PF05422.12 EMT51484.1 - 0.2 12.2 0.1 25 5.4 0.0 2.3 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) CbtA PF09490.10 EMT51484.1 - 0.2 11.4 0.1 20 4.9 0.0 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Spc24 PF08286.11 EMT51484.1 - 0.31 11.3 1.8 2.5 8.4 1.8 2.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Response_reg PF00072.24 EMT51485.1 - 2.5e-33 114.6 0.2 4.1e-33 113.9 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT51485.1 - 1.1e-23 83.1 0.1 3.7e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Transposase_mut PF00872.18 EMT51488.1 - 7.3e-15 54.7 0.0 8.8e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family EFG_C PF00679.24 EMT51488.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.4 1 1 0 1 1 1 0 Elongation factor G C-terminus RuvC PF02075.17 EMT51489.1 - 0.086 12.7 0.2 0.23 11.4 0.2 1.7 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC Peptidase_C97 PF05903.14 EMT51489.1 - 0.098 12.5 2.7 0.13 12.1 0.1 2.2 2 1 0 2 2 2 0 PPPDE putative peptidase domain ArAE_1_C PF11728.8 EMT51490.1 - 2.5e-51 174.0 4.7 3.1e-51 173.7 4.7 1.1 1 0 0 1 1 1 1 Putative aromatic acid exporter C-terminal domain ArAE_1 PF06081.11 EMT51490.1 - 1.1e-47 161.8 14.3 1.5e-47 161.3 14.3 1.2 1 0 0 1 1 1 1 Aromatic acid exporter family member 1 FUSC_2 PF13515.6 EMT51490.1 - 4.6e-09 36.5 14.5 5.3e-09 36.3 13.5 1.6 1 1 1 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 EMT51490.1 - 0.4 9.1 17.1 2.8 6.4 17.1 2.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family Colicin_V PF02674.16 EMT51490.1 - 5.7 6.9 15.6 2.1 8.3 3.4 3.0 3 0 0 3 3 3 0 Colicin V production protein SLH PF00395.20 EMT51491.1 - 3.1e-19 68.7 1.3 3.4e-08 33.4 0.0 3.2 3 0 0 3 3 3 2 S-layer homology domain DUF637 PF04830.13 EMT51491.1 - 0.00065 19.6 3.4 0.0038 17.1 3.4 2.4 1 1 0 1 1 1 1 Possible hemagglutinin (DUF637) ATP-synt_B PF00430.18 EMT51491.1 - 0.0081 16.2 10.1 0.015 15.4 10.1 1.4 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Response_reg PF00072.24 EMT51492.1 - 9.3e-28 96.6 0.0 1.3e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT51492.1 - 1.5e-27 95.4 0.0 3.2e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Fibroin_P25 PF07294.11 EMT51492.1 - 0.21 11.6 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Fibroin P25 HATPase_c PF02518.26 EMT51493.1 - 4.4e-26 91.6 0.0 7.7e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT51493.1 - 1e-16 60.7 0.0 3.1e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EMT51493.1 - 2.7e-15 56.5 0.0 6.1e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 EMT51493.1 - 7.9e-08 32.3 0.0 3.6e-07 30.2 0.0 2.0 1 1 1 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EMT51493.1 - 6.8e-05 22.7 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EMT51493.1 - 0.0003 20.6 0.0 0.00077 19.3 0.0 1.6 1 0 0 1 1 1 1 GHKL domain Apolipoprotein PF01442.18 EMT51493.1 - 0.017 15.0 0.7 0.081 12.8 0.5 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain adh_short PF00106.25 EMT51494.1 - 4.1e-31 107.9 0.0 2.3e-30 105.5 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMT51494.1 - 4.9e-31 108.1 0.1 8.5e-31 107.3 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMT51494.1 - 4e-06 26.9 0.2 8.1e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMT51494.1 - 0.067 12.6 0.5 0.15 11.5 0.2 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF2255 PF10012.9 EMT51494.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) SLH PF00395.20 EMT51495.1 - 1e-22 79.8 0.1 1.8e-08 34.2 0.0 3.6 3 0 0 3 3 3 3 S-layer homology domain DUF4901 PF16244.5 EMT51495.1 - 2.6e-08 33.5 0.8 2.9e-05 23.5 0.0 2.9 3 1 0 3 3 3 2 Domain of unknown function (DUF4901) PepSY PF03413.19 EMT51495.1 - 0.00078 20.0 8.2 0.2 12.2 0.0 6.0 6 0 0 6 6 6 1 Peptidase propeptide and YPEB domain DUF4901 PF16244.5 EMT51496.1 - 1.7e-16 60.3 0.1 2.1e-09 37.1 0.0 3.9 1 1 0 3 3 3 2 Domain of unknown function (DUF4901) PepSY PF03413.19 EMT51496.1 - 2.1e-06 28.2 4.0 1.7 9.3 0.0 5.8 5 2 0 5 5 5 3 Peptidase propeptide and YPEB domain FTP PF07504.13 EMT51496.1 - 0.00049 19.9 0.6 0.0013 18.5 0.6 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif TonB_2 PF13103.6 EMT51496.1 - 0.073 13.3 0.2 0.39 11.0 0.0 2.3 2 0 0 2 2 2 0 TonB C terminal Chlor_dismutase PF06778.12 EMT51497.1 - 7e-76 254.1 0.1 8.3e-76 253.9 0.1 1.0 1 0 0 1 1 1 1 Chlorite dismutase Glucosamine_iso PF01182.20 EMT51498.1 - 3.1e-24 86.1 0.0 5.4e-24 85.3 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.13 EMT51498.1 - 0.0002 20.6 0.3 0.092 11.9 0.1 2.5 2 1 0 2 2 2 2 Putative sugar-binding domain HTH_6 PF01418.17 EMT51499.1 - 1.2e-22 79.7 0.0 2.6e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 EMT51499.1 - 7.8e-22 77.5 0.8 1.1e-21 77.0 0.3 1.5 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 EMT51499.1 - 2.1e-07 31.0 0.5 8.7e-06 25.8 0.1 2.6 1 1 1 2 2 2 1 SIS domain HTH_50 PF18024.1 EMT51499.1 - 0.099 12.3 0.3 8.5 6.1 0.0 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain DUF1516 PF07457.11 EMT51500.1 - 2e-26 92.3 11.5 2.2e-26 92.1 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) SirB PF04247.12 EMT51500.1 - 3.5e-05 23.9 9.1 4.5e-05 23.5 9.1 1.1 1 0 0 1 1 1 1 Invasion gene expression up-regulator, SirB Ni_hydr_CYTB PF01292.20 EMT51500.1 - 0.00096 18.8 6.2 0.00096 18.8 6.2 1.6 1 1 1 2 2 2 1 Prokaryotic cytochrome b561 DUF998 PF06197.13 EMT51500.1 - 0.0036 16.9 3.7 0.0036 16.9 3.7 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF998) Cytochrom_B561 PF03188.16 EMT51500.1 - 0.016 15.4 4.9 0.053 13.6 4.8 2.0 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 DUF2678 PF10856.8 EMT51500.1 - 0.58 10.1 5.2 0.19 11.6 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) DUF3810 PF12725.7 EMT51500.1 - 5.7 6.2 10.6 1.6 8.0 5.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) dCMP_cyt_deam_1 PF00383.23 EMT51501.1 - 2.5e-25 88.3 2.7 5.2e-25 87.3 1.4 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMT51501.1 - 2.4e-24 85.6 0.2 5.7e-24 84.4 0.1 1.6 2 0 0 2 2 2 1 MafB19-like deaminase SNAD4 PF18750.1 EMT51501.1 - 0.028 14.6 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 OTT_1508_deam PF14441.6 EMT51501.1 - 0.063 13.3 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 OTT_1508-like deaminase Bd3614-deam PF14439.6 EMT51501.1 - 0.51 10.4 1.7 3.1 7.9 2.0 1.9 1 1 1 2 2 2 0 Bd3614-like deaminase YitT_membrane PF02588.15 EMT51502.1 - 8.1e-66 221.3 8.5 1e-65 221.0 8.5 1.1 1 0 0 1 1 1 1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DUF2179 PF10035.9 EMT51502.1 - 6.5e-20 70.6 0.0 1.1e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2179) Beta-lactamase2 PF13354.6 EMT51503.1 - 2.4e-58 197.1 0.1 3.1e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 EMT51503.1 - 2.1e-07 30.6 0.2 3.3e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Transpeptidase PF00905.22 EMT51503.1 - 0.00021 20.6 0.1 0.0023 17.2 0.0 2.0 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain Glutaminase PF04960.15 EMT51503.1 - 0.0015 17.8 0.2 0.021 14.0 0.0 2.0 1 1 0 2 2 2 1 Glutaminase Aldedh PF00171.22 EMT51504.1 - 9.7e-188 624.4 0.1 1.1e-187 624.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EMT51504.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EMT51504.1 - 0.21 11.0 0.0 4.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Arginase PF00491.21 EMT51505.1 - 3.7e-82 276.0 0.0 4.6e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family Prismane PF03063.20 EMT51507.1 - 3.9e-120 402.0 0.0 2.8e-102 343.1 0.0 2.0 1 1 1 2 2 2 2 Prismane/CO dehydrogenase family CutC PF03932.14 EMT51508.1 - 4.3e-61 205.9 0.4 5.1e-61 205.7 0.4 1.0 1 0 0 1 1 1 1 CutC family NMO PF03060.15 EMT51508.1 - 0.00082 18.9 0.5 0.0015 18.0 0.5 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase BtpA PF03437.15 EMT51508.1 - 0.0099 15.3 2.4 0.6 9.5 2.4 2.8 1 1 0 1 1 1 1 BtpA family PdxJ PF03740.13 EMT51508.1 - 0.059 12.5 0.3 0.54 9.3 0.0 2.4 3 0 0 3 3 3 0 Pyridoxal phosphate biosynthesis protein PdxJ HEPN PF05168.14 EMT51508.1 - 0.076 13.2 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 HEPN domain Peptidase_M17 PF00883.21 EMT51509.1 - 1.6e-94 316.7 0.0 2e-94 316.4 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EMT51509.1 - 1.3e-11 44.5 0.1 2.9e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Asparaginase_II PF06089.12 EMT51510.1 - 2.7e-94 315.8 0.0 3.1e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 L-asparaginase II WG_beta_rep PF14903.6 EMT51511.1 - 6.3e-14 52.0 0.2 5.2e-05 23.4 0.0 7.1 7 0 0 7 7 7 3 WG containing repeat NAD_binding_2 PF03446.15 EMT51512.1 - 7.3e-54 182.2 1.7 1.1e-53 181.7 1.7 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMT51512.1 - 4.1e-34 117.4 0.1 8.5e-34 116.4 0.1 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EMT51512.1 - 5.7e-10 39.7 0.1 1.1e-09 38.7 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EMT51512.1 - 6.4e-10 38.7 0.1 9.1e-10 38.2 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMT51512.1 - 1.4e-09 38.2 0.1 2e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EMT51512.1 - 1.5e-05 25.0 0.4 2.8e-05 24.1 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EMT51512.1 - 0.0001 22.0 0.1 0.00024 20.8 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 EMT51512.1 - 0.00015 21.4 1.4 0.00017 21.2 0.2 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 EMT51512.1 - 0.00041 19.7 0.6 0.00091 18.6 0.6 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EMT51512.1 - 0.00065 20.1 0.1 0.0028 18.1 0.1 2.1 1 1 0 1 1 1 1 Putative NAD(P)-binding adh_short PF00106.25 EMT51512.1 - 0.0075 15.7 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase OMPdecase PF00215.24 EMT51512.1 - 0.018 14.6 0.3 0.036 13.6 0.3 1.5 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Epimerase PF01370.21 EMT51512.1 - 0.024 14.1 0.0 1.4 8.3 0.0 2.1 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family DpaA_N PF16924.5 EMT51512.1 - 0.044 13.9 0.1 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain THF_DHG_CYH_C PF02882.19 EMT51512.1 - 0.044 13.1 0.3 0.55 9.5 0.3 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain POR PF01558.18 EMT51512.1 - 0.059 13.4 0.2 0.1 12.7 0.2 1.5 1 1 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase TrkA_N PF02254.18 EMT51512.1 - 0.095 13.0 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 EMT51512.1 - 0.097 12.6 0.2 0.31 11.0 0.2 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NmrA PF05368.13 EMT51512.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family AdoHcyase_NAD PF00670.21 EMT51512.1 - 0.11 12.5 0.4 0.21 11.7 0.4 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sigma54_activat PF00158.26 EMT51513.1 - 2.2e-72 242.2 0.0 5.1e-72 241.0 0.0 1.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT51513.1 - 2.6e-19 69.7 0.0 1e-18 67.7 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain PAS_9 PF13426.7 EMT51513.1 - 6.4e-12 45.7 0.1 5e-11 42.8 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EMT51513.1 - 1.9e-09 37.8 0.2 1.7e-08 34.7 0.0 2.7 3 0 0 3 3 3 1 PAS fold HTH_50 PF18024.1 EMT51513.1 - 8.6e-08 31.7 0.0 1.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain PAS PF00989.25 EMT51513.1 - 2.7e-07 30.6 0.0 1.5e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold AAA_5 PF07728.14 EMT51513.1 - 4.9e-06 26.6 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EMT51513.1 - 9.1e-05 22.9 0.0 0.00018 21.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EMT51513.1 - 0.00033 20.1 0.2 0.0047 16.3 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PAS_8 PF13188.7 EMT51513.1 - 0.0004 20.3 0.0 0.0016 18.4 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EMT51513.1 - 0.0066 16.7 0.1 0.15 12.4 0.0 2.9 3 0 0 3 3 2 1 PAS fold Sec8_exocyst PF04048.14 EMT51513.1 - 0.0099 15.8 0.5 2.5 8.0 0.2 2.9 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Fe_dep_repress PF01325.19 EMT51513.1 - 0.012 15.8 0.2 0.075 13.2 0.0 2.5 3 0 0 3 3 2 0 Iron dependent repressor, N-terminal DNA binding domain AAA_2 PF07724.14 EMT51513.1 - 0.023 14.8 0.0 0.066 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Phage_CII PF05269.11 EMT51513.1 - 0.04 14.1 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage CII protein HTH_38 PF13936.6 EMT51513.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EMT51513.1 - 0.11 12.5 0.5 0.43 10.6 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain AAA_7 PF12775.7 EMT51513.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_M20 PF01546.28 EMT51514.1 - 3.6e-36 124.8 0.1 4.8e-36 124.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT51514.1 - 4e-28 97.5 0.0 7.3e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT51514.1 - 7e-10 38.9 0.0 1.6e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.14 EMT51514.1 - 0.00014 21.0 0.0 0.00033 19.8 0.0 1.5 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase MFS_1 PF07690.16 EMT51515.1 - 9e-67 225.5 36.5 1.3e-59 201.9 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT51515.1 - 4.8e-19 68.6 18.2 2.4e-14 53.0 2.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EMT51515.1 - 3.4e-07 29.5 22.9 3.2e-05 23.0 13.5 2.3 2 0 0 2 2 2 2 MFS_1 like family Thioesterase PF00975.20 EMT51516.1 - 4.2e-44 151.4 0.0 4.7e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EMT51516.1 - 2.3e-05 25.1 0.0 3.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EMT51516.1 - 0.00024 20.8 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EMT51516.1 - 0.0019 17.5 0.0 0.025 13.8 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF900 PF05990.12 EMT51516.1 - 0.021 14.4 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Esterase PF00756.20 EMT51516.1 - 0.043 13.5 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 EMT51516.1 - 0.11 12.2 0.0 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold LAL_C2 PF18603.1 EMT51517.1 - 3.7e-23 81.5 0.1 6.5e-23 80.7 0.1 1.4 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_N PF18130.1 EMT51517.1 - 1.1e-08 35.5 0.0 1.9e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp PF02222.22 EMT51517.1 - 0.0041 16.7 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EMT51517.1 - 0.046 13.3 0.0 0.092 12.3 0.0 1.5 2 0 0 2 2 2 0 RimK-like ATP-grasp domain PALP PF00291.25 EMT51518.1 - 2.1e-45 155.4 0.0 2.4e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GHMP_kinases_N PF00288.26 EMT51519.1 - 1e-08 35.3 0.0 2.6e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMT51519.1 - 0.00011 22.5 0.1 0.00021 21.6 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Condensation PF00668.20 EMT51520.1 - 0 1198.2 0.3 6.7e-123 410.7 0.0 3.1 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 EMT51520.1 - 0 1008.3 0.0 6.8e-106 354.4 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme PP-binding PF00550.25 EMT51520.1 - 7.4e-48 160.8 0.3 1.2e-14 54.4 0.1 4.6 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EMT51520.1 - 2.4e-42 143.7 1.0 3.1e-13 50.5 0.0 4.7 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 EMT51520.1 - 1.9e-40 139.4 0.0 4.4e-40 138.2 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EMT51520.1 - 2.2e-06 28.4 0.0 5.3e-05 23.9 0.0 3.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family OmpA PF00691.20 EMT51520.1 - 0.038 14.4 0.1 41 4.6 0.0 3.3 3 0 0 3 3 3 0 OmpA family Abhydrolase_3 PF07859.13 EMT51520.1 - 0.044 13.6 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMT51520.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CTP_transf_like PF01467.26 EMT51520.1 - 0.21 11.8 1.0 1.2 9.4 0.1 2.6 3 0 0 3 3 3 0 Cytidylyltransferase-like AMP-binding PF00501.28 EMT51521.1 - 2.6e-292 968.5 0.0 3.7e-107 358.5 0.0 3.1 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EMT51521.1 - 9.5e-173 575.1 8.3 8.4e-115 384.0 0.0 2.8 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 EMT51521.1 - 1.7e-38 130.8 2.2 7.1e-16 58.3 0.0 4.0 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EMT51521.1 - 2.3e-28 99.0 0.1 1.9e-12 48.0 0.0 3.7 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Dehyd-heme_bind PF09098.10 EMT51521.1 - 0.053 13.1 0.0 6.1 6.4 0.0 3.1 3 0 0 3 3 3 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Penicil_amidase PF01804.18 EMT51522.1 - 2.8e-215 717.3 0.7 3.2e-215 717.1 0.7 1.0 1 0 0 1 1 1 1 Penicillin amidase HEPN_RnaseLS PF18869.1 EMT51522.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 RnaseLS-like HEPN MFS_1 PF07690.16 EMT51523.1 - 3.5e-43 147.9 53.9 7e-35 120.6 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT51523.1 - 4e-12 45.7 5.2 4e-12 45.7 5.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EMT51523.1 - 2.3e-11 43.2 24.0 2.6e-10 39.7 24.0 2.0 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 EMT51523.1 - 8.3e-05 21.2 9.0 0.0011 17.4 0.9 2.5 1 1 2 3 3 3 2 Transmembrane secretion effector Asn_synthase PF00733.21 EMT51524.1 - 4.8e-79 266.6 0.2 7.2e-79 266.0 0.2 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EMT51524.1 - 1.4e-41 141.3 0.0 2.8e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EMT51524.1 - 2.6e-34 118.3 0.1 8.6e-34 116.6 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain QueC PF06508.13 EMT51524.1 - 0.00021 20.8 0.0 0.00074 19.1 0.0 1.8 1 1 1 2 2 2 1 Queuosine biosynthesis protein QueC DUF3700 PF12481.8 EMT51524.1 - 0.02 14.4 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein NAD_synthase PF02540.17 EMT51524.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD synthase ATP_bind_3 PF01171.20 EMT51524.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 PP-loop family OpuAC PF04069.12 EMT51525.1 - 3.2e-71 239.9 4.0 3.7e-71 239.7 4.0 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system BPD_transp_1 PF00528.22 EMT51526.1 - 2.4e-20 73.0 21.6 2.4e-20 73.0 21.6 1.4 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EMT51527.1 - 4.7e-35 121.1 0.0 1.2e-34 119.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter CBS PF00571.28 EMT51527.1 - 6.8e-20 71.3 4.0 3e-09 37.2 0.1 3.3 4 0 0 4 4 3 2 CBS domain AAA_21 PF13304.6 EMT51527.1 - 2.3e-11 44.1 0.1 1.2e-06 28.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51527.1 - 1.3e-05 24.7 0.1 0.019 14.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMT51527.1 - 0.0002 21.8 0.0 0.00068 20.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT51527.1 - 0.00045 20.5 1.0 0.0021 18.3 0.1 2.4 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 EMT51527.1 - 0.0011 17.9 0.3 0.43 9.3 0.0 3.0 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 EMT51527.1 - 0.0012 18.6 0.0 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EMT51527.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EMT51527.1 - 0.0025 17.8 0.1 0.0044 17.0 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EMT51527.1 - 0.0034 17.8 0.3 0.024 15.1 0.3 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EMT51527.1 - 0.012 16.1 0.1 0.023 15.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EMT51527.1 - 0.014 15.3 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 EMT51527.1 - 0.014 15.8 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 EMT51527.1 - 0.015 14.9 0.1 0.069 12.7 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EMT51527.1 - 0.016 14.9 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EMT51527.1 - 0.018 14.3 0.1 1 8.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 EMT51527.1 - 0.021 14.8 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EMT51527.1 - 0.041 13.6 1.3 0.28 10.9 0.2 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EMT51527.1 - 0.1 12.5 0.3 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 EMT51527.1 - 0.12 11.8 0.4 1.1 8.6 0.1 2.4 3 0 0 3 3 3 0 KaiC AAA_7 PF12775.7 EMT51527.1 - 0.15 11.6 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EMT51527.1 - 0.22 11.7 0.5 1.2 9.2 0.3 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EMT51527.1 - 0.25 10.5 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 EMT51527.1 - 0.47 10.7 1.7 0.74 10.0 0.6 1.8 2 0 0 2 2 2 0 AAA domain DUF1116 PF06545.11 EMT51528.1 - 7.3e-05 22.3 3.9 0.24 10.9 0.1 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF1116) DUF4979 PF16351.5 EMT51528.1 - 0.0019 18.5 5.6 8.1 6.6 0.1 5.1 4 2 1 5 5 5 2 Domain of unknown function (DUF4979) End_beta_barrel PF12195.8 EMT51528.1 - 0.03 14.2 5.9 6.7 6.7 0.2 3.7 3 0 0 3 3 3 0 Beta barrel domain of bacteriophage endosialidase DUF2644 PF10841.8 EMT51528.1 - 0.038 14.2 0.8 18 5.6 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2644) GCV_T_C PF08669.11 EMT51528.1 - 0.086 12.8 6.0 2.6 8.0 0.1 3.8 4 1 0 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain Cerato-platanin PF07249.12 EMT51528.1 - 0.82 9.8 6.7 13 5.9 0.3 3.8 4 1 1 5 5 5 0 Cerato-platanin ABC_tran PF00005.27 EMT51529.1 - 1.5e-33 116.2 0.0 2.1e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT51529.1 - 2.4e-18 66.4 0.3 4.2e-18 65.6 0.3 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.6 EMT51529.1 - 0.00063 20.0 0.4 0.0037 17.6 0.4 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EMT51529.1 - 0.001 18.6 0.1 0.0034 16.9 0.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.25 EMT51529.1 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_21 PF13304.6 EMT51529.1 - 0.011 15.6 0.0 0.56 10.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMT51529.1 - 0.017 15.5 0.1 0.029 14.8 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EMT51529.1 - 0.031 13.7 0.4 0.52 9.7 0.1 2.3 2 1 0 2 2 2 0 Bacterial TniB protein PRK PF00485.18 EMT51529.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 EMT51529.1 - 0.17 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EMT51530.1 - 2.6e-30 105.7 0.0 3.7e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT51530.1 - 2.5e-20 72.7 0.1 4.9e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EMT51530.1 - 5.5e-08 32.5 0.7 2.1e-07 30.6 0.7 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT51530.1 - 2.3e-05 24.4 0.3 5.1e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMT51530.1 - 0.013 15.8 2.4 2.1 8.6 0.5 2.3 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EMT51530.1 - 0.018 14.4 1.2 0.24 10.8 0.1 2.4 2 1 0 2 2 2 0 Bacterial TniB protein ATP-synt_ab PF00006.25 EMT51530.1 - 0.033 13.8 0.2 0.051 13.2 0.2 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.9 EMT51530.1 - 0.13 11.1 0.3 0.51 9.1 0.3 1.7 1 1 0 1 1 1 0 Predicted ATPase of the ABC class BPD_transp_1 PF00528.22 EMT51531.1 - 1.3e-31 109.8 14.2 1.3e-31 109.8 14.2 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT51531.1 - 1.2e-08 34.8 0.2 1.2e-08 34.8 0.2 3.6 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 EMT51532.1 - 2.7e-43 147.9 12.9 2.7e-43 147.9 12.9 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2711 PF10924.8 EMT51532.1 - 0.025 14.2 0.0 0.046 13.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2711) SBP_bac_5 PF00496.22 EMT51533.1 - 8.3e-93 311.3 1.8 1.1e-92 310.9 1.8 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle SUZ PF12752.7 EMT51533.1 - 7 7.5 5.4 0.65 10.8 0.5 1.8 2 0 0 2 2 2 0 SUZ domain Peptidase_M20 PF01546.28 EMT51534.1 - 5.7e-36 124.2 0.4 9.3e-36 123.5 0.4 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT51534.1 - 1.7e-11 44.0 1.2 3.5e-11 43.0 0.3 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EMT51535.1 - 5.4e-38 130.8 0.0 7.1e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT51535.1 - 1.8e-15 56.8 0.0 2.9e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EMT51536.1 - 1.2e-23 83.9 1.1 1.9e-23 83.2 1.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT51536.1 - 6.6e-12 45.3 0.5 1.4e-11 44.3 0.5 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain PadR PF03551.14 EMT51537.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_28 PF13518.6 EMT51537.1 - 0.0061 16.7 0.1 0.016 15.3 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EMT51537.1 - 0.014 15.3 0.2 0.074 12.9 0.0 2.1 2 0 0 2 2 2 0 MarR family HTH_Crp_2 PF13545.6 EMT51537.1 - 0.032 14.2 1.5 0.064 13.2 0.1 2.2 3 1 0 3 3 3 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 EMT51537.1 - 0.048 14.0 0.3 6.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulator UPF0175 PF03683.13 EMT51537.1 - 0.094 12.4 0.0 3.9 7.2 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0175) HTH_29 PF13551.6 EMT51537.1 - 0.14 12.2 0.5 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn helix Peptidase_M20 PF01546.28 EMT51538.1 - 5.5e-27 94.8 0.4 1.2e-26 93.7 0.3 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT51538.1 - 6.2e-20 71.1 1.1 1.3e-19 70.2 1.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT51538.1 - 3e-05 23.8 0.0 0.00047 19.9 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M28 Trans_reg_C PF00486.28 EMT51539.1 - 7.3e-24 83.6 0.1 1.2e-23 82.9 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 EMT51539.1 - 1.3e-20 73.6 0.0 3.3e-20 72.3 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EMT51540.1 - 1e-11 44.7 0.9 1e-11 44.7 0.9 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 EMT51540.1 - 3.2e-07 30.9 0.0 9.9e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 EMT51540.1 - 1.3e-06 28.7 0.1 5.2e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 HAMP domain DUF5527 PF17665.1 EMT51540.1 - 0.038 13.5 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Macoilin PF09726.9 EMT51540.1 - 0.078 11.5 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Macoilin family HATPase_c_2 PF13581.6 EMT51540.1 - 0.093 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF3328 PF11807.8 EMT51540.1 - 0.11 12.2 0.1 0.71 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) FtsX PF02687.21 EMT51540.1 - 0.97 9.9 4.1 1.4 9.4 0.4 2.3 2 0 0 2 2 2 0 FtsX-like permease family ABC_tran PF00005.27 EMT51541.1 - 3.8e-30 105.2 0.0 2.1e-29 102.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EMT51541.1 - 6.6e-12 45.8 0.1 7.3e-07 29.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EMT51541.1 - 8.8e-06 26.4 0.0 1.8e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 EMT51541.1 - 0.014 15.8 0.0 0.023 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EMT51541.1 - 0.021 15.3 0.4 0.026 15.0 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMT51541.1 - 0.041 13.6 0.1 0.41 10.3 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EMT51541.1 - 0.054 13.8 0.0 0.34 11.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EMT51541.1 - 0.12 12.3 0.4 0.95 9.5 0.1 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EMT51541.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 EMT51541.1 - 0.16 12.4 0.1 1.9 8.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 EMT51541.1 - 0.17 11.3 0.0 9.7 5.6 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane_4 PF12730.7 EMT51542.1 - 4e-18 66.0 7.9 5.7e-18 65.5 7.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EMT51542.1 - 4.4e-05 22.9 10.2 4.4e-05 22.9 10.2 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 EMT51542.1 - 0.1 12.1 6.3 0.15 11.6 6.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 EMT51543.1 - 1.2e-23 84.0 7.2 1.2e-23 84.0 7.2 1.5 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EMT51543.1 - 5.3e-07 29.2 15.0 3e-06 26.7 15.0 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 EMT51543.1 - 8.3 5.4 19.1 43 3.1 19.1 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein Acetyltransf_1 PF00583.25 EMT51544.1 - 2.3e-23 82.6 0.4 2.9e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT51544.1 - 4.2e-16 59.1 0.1 1.1e-08 35.4 0.1 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT51544.1 - 1.4e-11 44.5 0.0 0.00018 21.4 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT51544.1 - 1.1e-05 25.5 0.0 0.0004 20.4 0.0 2.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT51544.1 - 3.7e-05 23.6 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_4 PF13420.7 EMT51544.1 - 0.0084 16.3 0.0 4.1 7.5 0.0 2.5 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain PanZ PF12568.8 EMT51544.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ BPD_transp_1 PF00528.22 EMT51545.1 - 1.4e-17 64.0 10.6 1.4e-17 64.0 10.6 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EMT51546.1 - 4.7e-12 46.0 23.0 1.2e-11 44.6 23.0 1.8 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF2207 PF09972.9 EMT51546.1 - 0.26 10.0 5.0 2.3 6.9 2.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SBP_bac_1 PF01547.25 EMT51547.1 - 4.1e-36 125.5 12.1 7e-36 124.8 12.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EMT51547.1 - 7.4e-30 104.7 5.9 1e-29 104.3 5.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EMT51547.1 - 4.8e-06 26.5 0.0 2.2e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein EFG_II PF14492.6 EMT51547.1 - 0.12 12.4 0.0 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Elongation Factor G, domain II SIS PF01380.22 EMT51548.1 - 8.9e-25 87.1 2.6 1.3e-24 86.5 2.6 1.3 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 EMT51548.1 - 5.8e-22 77.5 0.0 1.7e-21 76.0 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS_2 PF13580.6 EMT51548.1 - 2e-07 31.1 0.9 0.00028 20.9 0.2 2.6 1 1 1 2 2 2 2 SIS domain MarR_2 PF12802.7 EMT51548.1 - 0.00056 19.8 0.1 0.0059 16.5 0.0 2.6 3 0 0 3 3 3 1 MarR family IF2_N PF04760.15 EMT51548.1 - 0.0041 16.9 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region HTH_IclR PF09339.10 EMT51548.1 - 0.0082 15.9 0.0 0.068 13.0 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 EMT51548.1 - 0.015 14.8 0.0 0.059 12.9 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EMT51548.1 - 0.025 14.5 0.1 0.21 11.6 0.0 2.5 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain MarR PF01047.22 EMT51548.1 - 0.092 12.7 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 MarR family TusA PF01206.17 EMT51549.1 - 1.8e-24 85.4 0.0 1.9e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF3148 PF11347.8 EMT51549.1 - 0.14 12.0 0.0 0.64 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) DUF2249 PF10006.9 EMT51549.1 - 0.2 11.6 0.0 1.2 9.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Lactamase_B PF00753.27 EMT51550.1 - 2.2e-16 60.5 1.9 1e-15 58.3 1.9 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Rhodanese PF00581.20 EMT51550.1 - 6.1e-09 36.4 0.0 2.4e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Lactamase_B_2 PF12706.7 EMT51550.1 - 0.0018 17.8 0.1 0.0041 16.7 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DrsE_2 PF13686.6 EMT51551.1 - 7.3e-63 211.1 3.8 8.2e-63 210.9 3.8 1.0 1 0 0 1 1 1 1 DsrE/DsrF/DrsH-like family DrsE PF02635.15 EMT51551.1 - 7.3e-11 42.5 0.4 2.4e-09 37.6 0.4 2.0 1 1 0 1 1 1 1 DsrE/DsrF-like family DUF2048 PF09752.9 EMT51551.1 - 0.036 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Flavodoxin_5 PF12724.7 EMT51551.1 - 0.051 13.8 0.2 0.087 13.1 0.2 1.3 1 0 0 1 1 1 0 Flavodoxin domain Rho_N PF07498.12 EMT51551.1 - 0.068 13.1 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Trns_repr_metal PF02583.17 EMT51552.1 - 2e-23 82.6 3.0 2.2e-23 82.4 3.0 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor YojJ PF10372.9 EMT51552.1 - 0.12 12.5 0.1 0.28 11.3 0.1 1.6 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus Peripla_BP_6 PF13458.6 EMT51553.1 - 1.7e-47 162.8 3.7 2.1e-47 162.5 3.7 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 EMT51553.1 - 1.4e-08 34.3 0.0 2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 EMT51553.1 - 0.0006 18.9 0.9 0.0051 15.8 0.9 2.2 1 1 0 1 1 1 1 Periplasmic binding protein domain Fe-ADH PF00465.19 EMT51553.1 - 0.0044 15.9 0.0 0.012 14.4 0.0 1.7 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase TetR_C_28 PF17937.1 EMT51553.1 - 0.17 12.3 0.1 0.36 11.3 0.1 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PALP PF00291.25 EMT51554.1 - 3.8e-54 184.1 0.8 4.8e-54 183.8 0.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M14 PF00246.24 EMT51556.1 - 2.2e-45 155.7 0.2 3.7e-45 155.0 0.2 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Deltameth_res PF16020.5 EMT51556.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Deltamethrin resistance GGDEF PF00990.21 EMT51557.1 - 3.6e-42 143.9 0.0 1.4e-41 141.9 0.0 1.9 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain dCache_1 PF02743.18 EMT51557.1 - 1.6e-26 93.6 1.6 5.6e-26 91.8 0.3 2.0 2 0 0 2 2 2 1 Cache domain Cache_3-Cache_2 PF17201.4 EMT51557.1 - 7.4e-10 38.6 0.1 7.4e-10 38.6 0.1 1.6 2 0 0 2 2 2 1 Cache 3/Cache 2 fusion domain sCache_3_2 PF17203.4 EMT51557.1 - 1.7e-07 31.5 0.0 0.01 16.0 0.0 2.4 2 0 0 2 2 2 2 Single cache domain 3 GGDEF_2 PF17853.1 EMT51557.1 - 0.00034 20.9 0.0 0.00094 19.4 0.0 1.8 1 0 0 1 1 1 1 GGDEF-like domain CHASE4 PF05228.13 EMT51557.1 - 0.0024 18.1 0.0 0.38 11.0 0.0 2.7 3 0 0 3 3 3 1 CHASE4 domain sCache_2 PF17200.4 EMT51557.1 - 0.037 13.9 0.1 0.08 12.8 0.1 1.5 1 0 0 1 1 1 0 Single Cache domain 2 dCache_2 PF08269.11 EMT51557.1 - 0.048 12.8 0.4 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Cache domain GRDA PF04723.14 EMT51557.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A Phage_Mu_Gam PF07352.12 EMT51557.1 - 0.27 11.1 3.8 3.2 7.6 0.2 2.7 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein PGA_cap PF09587.10 EMT51558.1 - 2.4e-72 243.5 0.1 3.1e-72 243.1 0.1 1.2 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Metallophos PF00149.28 EMT51558.1 - 0.0009 19.8 0.0 0.0022 18.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AMP-binding PF00501.28 EMT51560.1 - 6.9e-108 361.0 0.0 9.5e-108 360.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMT51560.1 - 2.4e-23 82.9 2.0 6.3e-23 81.6 2.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LytR_cpsA_psr PF03816.14 EMT51561.1 - 1.6e-45 155.0 0.1 2.7e-45 154.2 0.1 1.4 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain adh_short_C2 PF13561.6 EMT51562.1 - 3.3e-63 213.4 1.8 3.8e-63 213.2 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT51562.1 - 7.5e-58 195.2 3.7 1.1e-57 194.7 3.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT51562.1 - 5.2e-09 36.3 0.3 7.6e-09 35.7 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMT51562.1 - 0.005 16.3 0.8 0.13 11.7 0.8 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EMT51562.1 - 0.012 16.3 0.1 0.055 14.2 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain PALP PF00291.25 EMT51562.1 - 0.03 13.7 2.9 0.055 12.9 0.3 2.0 1 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme 3HCDH_N PF02737.18 EMT51562.1 - 0.055 13.4 0.3 0.098 12.5 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_S11 PF00411.19 EMT51562.1 - 0.54 10.7 2.7 0.47 10.9 0.7 1.9 2 0 0 2 2 2 0 Ribosomal protein S11 MarR PF01047.22 EMT51563.1 - 7e-11 41.9 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EMT51563.1 - 2.8e-09 36.7 0.0 5.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EMT51563.1 - 5.5e-09 36.4 0.0 8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EMT51563.1 - 2.1e-06 27.2 0.0 3.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 EMT51563.1 - 1.2e-05 25.3 0.1 2.1e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 EMT51563.1 - 0.0015 18.3 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 EMT51563.1 - 0.002 18.3 0.2 0.005 17.0 0.2 1.7 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 EMT51563.1 - 0.0039 17.0 0.1 0.0065 16.3 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EMT51563.1 - 0.024 15.0 0.4 0.052 13.9 0.1 1.7 2 0 0 2 2 1 0 Transcriptional regulator RQC PF09382.10 EMT51563.1 - 0.051 13.4 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 RQC domain HTH_6 PF01418.17 EMT51563.1 - 0.054 13.5 0.3 0.3 11.1 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family HTH_45 PF14947.6 EMT51563.1 - 0.055 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_5 PF01022.20 EMT51563.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TFIIE_alpha PF02002.17 EMT51563.1 - 0.069 13.0 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 TFIIE alpha subunit DUF2313 PF10076.9 EMT51563.1 - 0.13 12.1 0.1 0.4 10.5 0.0 1.6 1 1 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) FCD PF07729.12 EMT51563.1 - 0.14 12.6 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 FCD domain Na_H_antiporter PF03553.14 EMT51564.1 - 1.9e-56 191.5 23.1 1.9e-56 191.5 23.1 2.3 1 1 1 2 2 2 1 Na+/H+ antiporter family DcuC PF03606.15 EMT51564.1 - 2.6e-07 29.5 21.3 1e-06 27.5 16.0 2.4 2 0 0 2 2 2 2 C4-dicarboxylate anaerobic carrier CitMHS PF03600.16 EMT51564.1 - 0.039 13.2 44.4 20 4.3 27.9 2.3 1 1 1 2 2 2 0 Citrate transporter Arc_PepC_II PF06847.11 EMT51564.1 - 0.065 13.7 0.5 14 6.3 0.1 2.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II AlaDh_PNT_C PF01262.21 EMT51565.1 - 1.7e-55 187.7 0.1 2.2e-55 187.3 0.1 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EMT51565.1 - 2.4e-33 115.3 0.0 4.3e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 EMT51565.1 - 2.9e-08 33.3 0.0 3.1e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMT51565.1 - 0.00015 21.8 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EMT51565.1 - 0.00023 21.1 0.0 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EMT51565.1 - 0.0003 21.3 0.2 0.0013 19.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 EMT51565.1 - 0.00033 20.9 0.3 0.0006 20.0 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.6 EMT51565.1 - 0.00078 19.6 0.6 0.15 12.3 0.5 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AdoHcyase_NAD PF00670.21 EMT51565.1 - 0.0036 17.4 0.6 0.012 15.7 0.6 1.8 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 EMT51565.1 - 0.0072 16.8 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EMT51565.1 - 0.0092 15.3 1.4 0.014 14.6 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMT51565.1 - 0.013 14.7 0.4 0.032 13.5 0.3 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EMT51565.1 - 0.02 14.5 0.6 0.098 12.2 0.6 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EMT51565.1 - 0.027 14.7 0.1 0.076 13.3 0.1 1.9 1 1 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 EMT51565.1 - 0.042 13.5 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 EMT51565.1 - 0.068 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain GIDA PF01134.22 EMT51565.1 - 0.15 11.1 0.2 0.25 10.4 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 EMT51565.1 - 0.16 12.2 0.1 0.43 10.8 0.1 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sigma54_activat PF00158.26 EMT51567.1 - 3.7e-61 205.7 0.0 5.4e-61 205.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT51567.1 - 3.9e-23 82.1 0.0 1.7e-22 80.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 EMT51567.1 - 5e-11 42.2 0.2 1.7e-10 40.5 0.2 2.0 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 EMT51567.1 - 5.4e-09 36.2 0.0 1.3e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMT51567.1 - 1.7e-05 24.3 0.0 0.019 14.4 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM PF00493.23 EMT51567.1 - 4e-05 22.8 0.0 7.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain dCache_3 PF14827.6 EMT51567.1 - 0.00014 21.6 0.0 0.00035 20.3 0.0 1.6 1 1 0 1 1 1 1 Double sensory domain of two-component sensor kinase AAA PF00004.29 EMT51567.1 - 0.00015 22.2 0.0 0.00035 21.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EMT51567.1 - 0.00032 20.8 0.0 0.0012 18.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PAS_9 PF13426.7 EMT51567.1 - 0.0044 17.3 0.1 0.011 15.9 0.1 1.8 1 0 0 1 1 1 1 PAS domain H_kinase_N PF12282.8 EMT51567.1 - 0.014 15.4 0.0 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 Signal transduction histidine kinase PAS_4 PF08448.10 EMT51567.1 - 0.045 14.0 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 PAS fold sCache_3_2 PF17203.4 EMT51567.1 - 0.14 12.3 0.0 0.87 9.7 0.0 2.2 1 1 0 1 1 1 0 Single cache domain 3 Lyase_1 PF00206.20 EMT51568.1 - 1.2e-109 366.5 0.6 1.5e-109 366.2 0.6 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EMT51568.1 - 5.1e-21 74.8 0.1 1.4e-20 73.4 0.1 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus MFS_1 PF07690.16 EMT51569.1 - 4e-47 160.9 44.3 1e-39 136.5 36.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT51569.1 - 4.9e-07 29.0 22.0 2.9e-06 26.4 22.0 1.9 1 1 0 1 1 1 1 MFS_1 like family MarR PF01047.22 EMT51570.1 - 2.6e-17 62.5 0.1 5.7e-17 61.4 0.0 1.6 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EMT51570.1 - 7e-12 45.1 0.1 1.1e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EMT51570.1 - 3.1e-10 40.4 0.1 7.6e-10 39.2 0.1 1.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_34 PF13601.6 EMT51570.1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 EMT51570.1 - 0.0028 17.5 0.0 0.0083 16.0 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HxlR PF01638.17 EMT51570.1 - 0.0051 16.6 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_24 PF13412.6 EMT51570.1 - 0.0082 15.7 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding PadR PF03551.14 EMT51570.1 - 0.011 15.7 0.1 0.025 14.5 0.1 1.7 1 1 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 EMT51570.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4423 PF14394.6 EMT51570.1 - 0.037 13.7 0.0 0.084 12.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) DUF2250 PF10007.9 EMT51570.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) FeoC PF09012.10 EMT51570.1 - 0.1 12.7 0.1 0.59 10.2 0.0 1.9 2 0 0 2 2 2 0 FeoC like transcriptional regulator Fe_dep_repress PF01325.19 EMT51570.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HATPase_c PF02518.26 EMT51571.1 - 1.1e-28 99.9 0.1 2.9e-28 98.6 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT51571.1 - 7.6e-16 57.9 1.1 2e-15 56.6 1.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EMT51571.1 - 0.00011 22.1 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EMT51571.1 - 0.0005 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 EMT51571.1 - 0.062 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain SCP2 PF02036.17 EMT51571.1 - 0.12 12.9 0.0 21 5.6 0.0 2.7 2 0 0 2 2 2 0 SCP-2 sterol transfer family Response_reg PF00072.24 EMT51572.1 - 3.5e-28 98.0 0.0 5.6e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT51572.1 - 4.4e-22 78.0 0.2 2e-21 75.8 0.1 2.0 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal ACR_tran PF00873.19 EMT51573.1 - 4.3e-279 928.5 30.3 4.9e-279 928.3 30.3 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EMT51573.1 - 5.5e-14 51.8 25.2 5.3e-09 35.5 11.0 2.7 2 0 0 2 2 2 2 MMPL family Asp23 PF03780.13 EMT51573.1 - 0.8 10.1 6.7 14 6.2 0.1 4.3 5 0 0 5 5 5 0 Asp23 family, cell envelope-related function HlyD_D23 PF16576.5 EMT51574.1 - 3.8e-22 78.6 14.2 2.3e-20 72.8 14.2 2.3 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EMT51574.1 - 1e-17 64.8 9.2 2.5e-14 53.9 2.2 3.0 3 0 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EMT51574.1 - 2.1e-10 40.3 2.2 2.1e-10 40.3 2.2 4.0 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_2 PF12700.7 EMT51574.1 - 1.6e-09 37.0 8.8 9.6e-09 34.5 8.8 2.2 1 1 0 1 1 1 1 HlyD family secretion protein Biotin_lipoyl PF00364.22 EMT51574.1 - 7.6e-09 35.3 3.3 1.2e-05 25.0 0.1 3.1 2 1 0 2 2 2 2 Biotin-requiring enzyme OEP PF02321.18 EMT51574.1 - 0.0008 19.3 18.7 0.0008 19.3 18.7 2.8 1 1 1 2 2 2 1 Outer membrane efflux protein SHOCT PF09851.9 EMT51574.1 - 0.0016 18.1 0.6 0.0016 18.1 0.6 2.3 2 0 0 2 2 2 1 Short C-terminal domain PTS_EIIA_1 PF00358.20 EMT51574.1 - 0.0046 16.7 0.6 0.036 13.8 0.0 2.3 2 0 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PYNP_C PF07831.13 EMT51574.1 - 0.043 13.5 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain RnfC_N PF13375.6 EMT51574.1 - 0.091 12.7 3.4 0.17 11.9 0.5 3.0 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain She9_MDM33 PF05546.11 EMT51574.1 - 1.4 8.7 6.1 2.4 7.9 6.1 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family DUF2680 PF10925.8 EMT51575.1 - 5.8e-13 48.6 18.5 0.00022 21.2 3.3 3.9 3 1 1 4 4 4 3 Protein of unknown function (DUF2680) Phage_XkdX PF09693.10 EMT51575.1 - 3.2e-09 36.6 1.6 0.12 12.4 0.0 3.6 3 0 0 3 3 3 3 Phage uncharacterised protein (Phage_XkdX) RHH_4 PF13467.6 EMT51575.1 - 1.9e-07 30.9 1.5 0.28 11.1 0.0 3.5 3 0 0 3 3 3 2 Ribbon-helix-helix domain CT_C_D PF02682.16 EMT51575.1 - 8.7e-06 25.6 2.4 0.5 10.1 0.0 3.8 3 2 0 3 3 3 2 Carboxyltransferase domain, subdomain C and D TnsD PF15978.5 EMT51575.1 - 6.5e-05 22.1 14.2 0.14 11.1 1.1 3.1 3 0 0 3 3 3 3 Tn7-like transposition protein D ScdA_N PF04405.14 EMT51575.1 - 0.00022 20.8 3.4 1.3 8.8 0.1 4.1 3 0 0 3 3 3 1 Domain of Unknown function (DUF542) LpxI_N PF17930.1 EMT51575.1 - 0.0022 17.9 6.8 0.51 10.2 0.4 3.3 2 1 1 3 3 3 2 LpxI N-terminal domain DUF1707 PF08044.11 EMT51575.1 - 0.0048 16.9 7.1 9.8 6.3 0.1 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) HTH_Tnp_1 PF01527.20 EMT51575.1 - 0.006 16.9 11.6 0.88 9.9 0.9 3.4 3 0 0 3 3 3 2 Transposase HTH_38 PF13936.6 EMT51575.1 - 0.0086 15.8 0.0 34 4.3 0.0 3.6 3 0 0 3 3 3 0 Helix-turn-helix domain ODC_AZ PF02100.17 EMT51575.1 - 0.0092 15.9 1.3 6 6.9 0.0 3.3 3 0 0 3 3 3 1 Ornithine decarboxylase antizyme SRP_SPB PF02978.19 EMT51575.1 - 0.015 15.9 6.6 2.9 8.6 0.3 3.9 3 3 0 3 3 3 0 Signal peptide binding domain Mg_chelatase_C PF13335.6 EMT51575.1 - 0.19 12.4 7.5 5.7 7.6 0.1 4.4 2 2 3 5 5 5 0 Magnesium chelatase, subunit ChlI C-terminal PAS_4 PF08448.10 EMT51575.1 - 0.22 11.8 0.8 28 5.0 0.0 3.1 3 0 0 3 3 3 0 PAS fold IF2_N PF04760.15 EMT51575.1 - 0.36 10.7 13.8 2.7 7.9 0.1 5.3 4 3 1 5 5 4 0 Translation initiation factor IF-2, N-terminal region His_Phos_2 PF00328.22 EMT51575.1 - 0.4 10.0 7.0 0.14 11.4 0.1 2.6 1 1 2 3 3 3 0 Histidine phosphatase superfamily (branch 2) DUF3071 PF11268.8 EMT51575.1 - 0.41 10.7 19.3 2.7 8.0 2.4 3.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3071) KdpC PF02669.15 EMT51575.1 - 0.47 10.3 8.3 10 5.9 0.1 3.9 3 1 0 3 3 3 0 K+-transporting ATPase, c chain FumaraseC_C PF10415.9 EMT51575.1 - 0.47 10.9 16.6 3.2 8.3 1.3 6.0 3 3 1 4 4 4 0 Fumarase C C-terminus DUF952 PF06108.12 EMT51575.1 - 0.6 10.1 3.8 95 3.1 0.1 3.8 3 2 0 3 3 3 0 Protein of unknown function (DUF952) Ribosomal_S13 PF00416.22 EMT51575.1 - 0.8 10.1 9.8 21 5.5 0.5 3.5 3 0 0 3 3 3 0 Ribosomal protein S13/S18 FCSD-flav_bind PF09242.11 EMT51575.1 - 0.86 10.0 8.1 12 6.3 0.2 3.7 4 0 0 4 4 4 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding UreF PF01730.16 EMT51575.1 - 1.1 9.8 11.7 4.5 7.9 0.1 3.8 4 1 0 4 4 3 0 UreF NLRC4_HD2 PF17776.1 EMT51575.1 - 1.1 9.8 8.5 18 5.9 0.4 3.4 3 1 0 3 3 3 0 NLRC4 helical domain HD2 Arg_decarbox_C PF17944.1 EMT51575.1 - 2.7 8.6 19.7 3.2 8.4 0.5 5.6 4 2 2 6 6 6 0 Arginine decarboxylase C-terminal helical extension Sigma70_r3 PF04539.16 EMT51575.1 - 2.7 8.1 17.9 0.94 9.6 1.3 4.4 3 2 1 4 4 4 0 Sigma-70 region 3 PAS_7 PF12860.7 EMT51575.1 - 4.8 7.4 5.6 12 6.1 0.4 3.4 3 2 0 3 3 3 0 PAS fold TFIID-31kDa PF02291.15 EMT51575.1 - 5.1 7.2 8.4 8.2 6.5 0.2 2.9 3 0 0 3 3 3 0 Transcription initiation factor IID, 31kD subunit DUF2774 PF11242.8 EMT51575.1 - 6.7 7.0 6.3 13 6.0 0.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2774) TctC PF03401.14 EMT51576.1 - 4.2e-47 160.5 0.2 5.1e-47 160.2 0.2 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter family receptor STI1 PF17830.1 EMT51576.1 - 0.0058 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 STI1 domain TACC_C PF05010.14 EMT51576.1 - 0.033 14.0 0.1 0.045 13.5 0.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TctA PF01970.16 EMT51577.1 - 7.1e-145 482.8 40.0 1.1e-144 482.2 40.0 1.3 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctA family Ca_hom_mod PF14798.6 EMT51577.1 - 0.17 11.0 1.9 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Calcium homeostasis modulator TctB PF07331.11 EMT51578.1 - 1.9e-20 73.5 7.6 2.3e-20 73.2 7.6 1.0 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family CrgA PF06781.12 EMT51578.1 - 0.079 13.0 0.1 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 Cell division protein CrgA TM_helix PF05552.12 EMT51578.1 - 0.47 10.5 8.9 0.36 10.8 3.2 2.4 2 0 0 2 2 2 0 Conserved TM helix TPR_MalT PF17874.1 EMT51579.1 - 2.6e-27 96.1 4.3 2.6e-27 96.1 4.3 2.2 2 0 0 2 2 2 1 MalT-like TPR region GerE PF00196.19 EMT51579.1 - 9e-16 57.2 0.2 2.9e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EMT51579.1 - 0.00033 20.3 0.0 0.0011 18.6 0.0 2.0 1 0 0 1 1 1 1 Sigma-70, region 4 AAA_16 PF13191.6 EMT51579.1 - 0.00067 20.1 0.0 0.0034 17.8 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain HTH_24 PF13412.6 EMT51579.1 - 0.0092 15.5 0.0 0.026 14.1 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 EMT51579.1 - 0.017 14.7 0.0 0.046 13.2 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 EMT51579.1 - 0.017 14.9 0.3 0.23 11.3 0.0 3.1 2 1 0 2 2 2 0 Homeodomain-like domain AAA_22 PF13401.6 EMT51579.1 - 0.024 14.9 0.0 0.075 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain HTH_Tnp_ISL3 PF13542.6 EMT51579.1 - 0.027 13.9 0.2 5.3 6.5 0.0 3.7 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 EMT51579.1 - 0.04 14.0 0.3 8.3 6.5 0.0 3.2 3 0 0 3 3 3 0 Winged helix-turn helix ANAPC5 PF12862.7 EMT51579.1 - 0.047 13.8 0.0 22 5.2 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 HTH_10 PF04967.12 EMT51579.1 - 0.047 13.5 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain HSBP1 PF06825.12 EMT51579.1 - 0.076 12.9 0.3 0.26 11.2 0.0 2.1 2 0 0 2 2 1 0 Heat shock factor binding protein 1 HTH_7 PF02796.15 EMT51579.1 - 0.094 12.8 0.0 0.84 9.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase TPR_19 PF14559.6 EMT51579.1 - 0.14 12.7 6.0 19 5.8 0.1 4.3 3 1 2 5 5 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMT51579.1 - 5.2 7.4 9.3 6.7 7.1 0.3 4.4 5 1 1 6 6 4 0 Tetratricopeptide repeat TBK1_CCD1 PF18394.1 EMT51581.1 - 0.074 12.6 0.3 0.24 10.9 0.1 1.7 1 1 1 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 zf-C2H2_4 PF13894.6 EMT51581.1 - 0.14 13.0 1.1 0.14 13.0 1.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger DisA_N PF02457.16 EMT51582.1 - 4.3e-39 132.8 0.0 6.2e-39 132.3 0.0 1.2 1 0 0 1 1 1 1 DisA bacterial checkpoint controller nucleotide-binding YojJ PF10372.9 EMT51582.1 - 2.1e-17 63.0 0.6 2.9e-17 62.5 0.6 1.2 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus Aminotran_5 PF00266.19 EMT51583.1 - 1.5e-74 251.2 0.0 4.1e-74 249.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EMT51583.1 - 5.1e-08 31.9 0.0 8.1e-08 31.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EMT51583.1 - 0.0037 16.6 0.1 0.0057 16.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family WYL PF13280.6 EMT51584.1 - 1.5e-39 135.8 2.4 2e-39 135.4 2.4 1.2 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 EMT51584.1 - 3.8e-15 55.6 0.0 7.1e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_DeoR PF08220.12 EMT51584.1 - 1.3e-06 28.0 0.1 3.4e-06 26.7 0.1 1.7 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 EMT51584.1 - 1.4e-05 25.4 0.1 3e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_AsnC-type PF13404.6 EMT51584.1 - 0.00011 22.0 0.4 0.00023 20.9 0.4 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 EMT51584.1 - 0.00017 21.0 0.3 0.00034 20.1 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 EMT51584.1 - 0.0051 16.8 0.1 0.013 15.5 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 EMT51584.1 - 0.012 15.4 0.1 0.047 13.5 0.1 2.0 1 0 0 1 1 1 0 Homeodomain-like domain TrmB PF01978.19 EMT51584.1 - 0.034 14.0 0.1 0.72 9.8 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 EMT51584.1 - 0.07 13.1 0.5 0.22 11.5 0.5 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TetR_N PF00440.23 EMT51585.1 - 4.1e-11 42.5 0.1 8.5e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_N PF00440.23 EMT51586.1 - 4.5e-13 48.8 0.4 2e-12 46.7 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 EMT51586.1 - 0.031 14.4 0.1 0.41 10.8 0.0 2.3 1 1 0 2 2 2 0 Helix-turn-helix of insertion element transposase Symplekin_C PF12295.8 EMT51586.1 - 0.057 13.5 0.1 0.11 12.6 0.1 1.5 1 1 0 1 1 1 0 Symplekin tight junction protein C terminal IPPT PF01715.17 EMT51586.1 - 0.067 13.0 0.3 0.083 12.7 0.3 1.3 1 0 0 1 1 1 0 IPP transferase HD PF01966.22 EMT51586.1 - 0.19 11.9 0.8 0.78 10.0 0.6 2.1 1 1 1 2 2 2 0 HD domain Y_phosphatase3 PF13350.6 EMT51587.1 - 7.9e-61 206.0 0.0 8.9e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EMT51587.1 - 4.3e-07 29.6 0.1 8.4e-07 28.7 0.1 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 EMT51587.1 - 0.00025 20.8 0.1 0.0019 17.9 0.1 2.2 2 1 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Myotub-related PF06602.14 EMT51587.1 - 0.0014 17.7 0.1 0.0038 16.2 0.0 1.6 1 1 1 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 EMT51587.1 - 0.058 13.0 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DoxX PF07681.12 EMT51588.1 - 0.00051 20.6 10.9 0.0016 19.0 10.9 1.8 1 1 0 1 1 1 1 DoxX DUF485 PF04341.12 EMT51588.1 - 0.49 10.4 3.9 1.4 8.9 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Flavin_Reduct PF01613.18 EMT51589.1 - 4.5e-11 43.0 0.0 5.9e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Putative_PNPOx PF01243.20 EMT51589.1 - 2.9e-06 27.4 0.0 4.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.12 EMT51589.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF447) SnoaL_2 PF12680.7 EMT51590.1 - 7.9e-17 61.8 0.6 9.8e-17 61.5 0.6 1.1 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 EMT51590.1 - 6.4e-07 30.0 0.0 9.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL PF07366.12 EMT51590.1 - 1.7e-06 27.8 0.2 0.0039 17.0 0.0 2.1 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase DUF4440 PF14534.6 EMT51590.1 - 6.1e-05 23.4 0.1 8.2e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 EMT51590.1 - 8.2e-05 22.9 0.1 0.00024 21.4 0.1 1.8 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 EMT51590.1 - 0.0012 19.0 0.1 0.0014 18.7 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.7 EMT51590.1 - 0.019 15.6 0.0 0.024 15.3 0.0 1.3 1 1 0 1 1 1 0 Putative lumazine-binding CBM_11 PF03425.13 EMT51590.1 - 0.076 12.9 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) DUF4272 PF14094.6 EMT51591.1 - 3.3e-78 261.7 0.6 4.7e-78 261.2 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4272) SUFU PF05076.13 EMT51592.1 - 3.3e-22 79.3 0.1 6.3e-22 78.4 0.0 1.4 2 0 0 2 2 2 1 Suppressor of fused protein (SUFU) HicA_toxin PF07927.12 EMT51594.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, B3 PF02362.21 EMT51594.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 B3 DNA binding domain Peptidase_M28 PF04389.17 EMT51595.1 - 3.2e-24 85.7 0.0 7e-24 84.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 EMT51595.1 - 4.3e-22 78.5 1.6 9.8e-22 77.3 0.1 2.1 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain PA PF02225.22 EMT51595.1 - 1.1e-10 41.3 0.1 4.4e-10 39.4 0.1 2.1 1 1 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EMT51595.1 - 0.0031 17.2 0.6 0.012 15.3 0.1 2.1 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 SpoIISA_toxin PF14171.6 EMT51595.1 - 0.023 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system HTH_52 PF18576.1 EMT51595.1 - 0.063 13.5 0.1 18 5.7 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain RP-C PF03428.13 EMT51595.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF4347 PF14252.6 EMT51595.1 - 0.14 12.0 0.2 0.33 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) PPR_3 PF13812.6 EMT51595.1 - 0.22 11.6 0.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Sod_Cu PF00080.20 EMT51597.1 - 3.3e-33 114.8 0.0 4.3e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Cupin_2 PF07883.11 EMT51598.1 - 3.9e-12 45.7 0.9 5.3e-12 45.3 0.9 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.7 EMT51598.1 - 2.6e-05 24.1 0.2 3.7e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain ARD PF03079.14 EMT51598.1 - 4.2e-05 23.8 0.6 5.2e-05 23.5 0.6 1.2 1 0 0 1 1 1 1 ARD/ARD' family AraC_binding PF02311.19 EMT51598.1 - 0.00026 20.9 0.1 0.00031 20.6 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain 3-HAO PF06052.12 EMT51598.1 - 0.0037 16.9 0.1 0.0045 16.6 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase MannoseP_isomer PF01050.18 EMT51598.1 - 0.0065 16.4 0.1 0.0068 16.3 0.1 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Colicin-DNase PF12639.7 EMT51598.1 - 0.01 16.6 0.0 0.017 15.9 0.0 1.3 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin DUF4863 PF16155.5 EMT51598.1 - 0.015 15.2 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4863) WHH PF14414.6 EMT51598.1 - 0.02 14.7 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH EutQ PF06249.12 EMT51598.1 - 0.022 14.5 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_1 PF00190.22 EMT51598.1 - 0.025 14.2 0.0 0.042 13.4 0.0 1.5 1 1 0 1 1 1 0 Cupin Cupin_3 PF05899.12 EMT51598.1 - 0.099 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Mem_trans PF03547.18 EMT51600.1 - 4.2e-24 84.7 31.9 6.5e-15 54.4 13.8 2.0 1 1 1 2 2 2 2 Membrane transport protein Sulf_transp PF04143.14 EMT51601.1 - 4e-97 325.5 32.2 4.8e-97 325.2 32.2 1.1 1 0 0 1 1 1 1 Sulphur transport DUF2534 PF10749.9 EMT51601.1 - 0.19 11.9 4.3 1.3 9.2 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2534) TusA PF01206.17 EMT51602.1 - 1.4e-19 69.6 0.0 1.6e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 EMT51602.1 - 0.012 15.5 0.3 0.12 12.2 0.3 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Catalase PF00199.19 EMT51603.1 - 8.7e-204 676.8 0.5 2.7e-203 675.2 0.4 1.7 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.12 EMT51603.1 - 1.5e-27 95.6 0.1 2.8e-27 94.7 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Protoglobin PF11563.8 EMT51604.1 - 5.1e-32 110.9 1.3 5.1e-32 110.9 1.3 2.0 2 0 0 2 2 2 1 Protoglobin MCPsignal PF00015.21 EMT51604.1 - 3.6e-29 101.8 6.0 3.6e-29 101.8 6.0 1.8 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Cyt_bd_oxida_I PF01654.17 EMT51604.1 - 0.05 12.2 0.1 0.057 12.0 0.1 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I BLOC1_2 PF10046.9 EMT51604.1 - 0.27 11.6 15.5 1.6 9.1 3.5 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 EMT51604.1 - 0.4 10.7 9.7 2.5 8.1 1.1 2.5 2 0 0 2 2 2 0 Laminin Domain II Fez1 PF06818.15 EMT51604.1 - 0.46 10.9 6.8 0.41 11.1 5.1 1.8 2 0 0 2 2 2 0 Fez1 EMP24_GP25L PF01105.24 EMT51604.1 - 0.49 10.3 7.0 2 8.4 5.2 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF948 PF06103.11 EMT51604.1 - 0.77 10.1 9.7 2.9 8.2 0.7 2.8 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 EMT51604.1 - 0.83 10.2 5.8 32 5.1 5.8 2.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 WXG100 PF06013.12 EMT51604.1 - 0.92 9.8 7.7 5.8 7.2 1.5 3.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Seryl_tRNA_N PF02403.22 EMT51604.1 - 1.7 8.9 6.7 17 5.7 0.9 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 EMT51604.1 - 1.8 7.8 10.5 1.6 7.9 1.5 2.3 1 1 1 2 2 2 0 TMPIT-like protein Flagellin_N PF00669.20 EMT51604.1 - 2.3 8.3 10.7 0.36 10.9 1.9 2.6 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region Cob_adeno_trans PF01923.18 EMT51604.1 - 3.9 7.6 7.5 5.7 7.0 0.9 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Phosphodiest PF01663.22 EMT51605.1 - 5.5e-15 55.8 0.6 7.6e-15 55.4 0.6 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EMT51605.1 - 0.0097 15.3 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 Sulfatase DUF881 PF05949.12 EMT51605.1 - 0.1 12.5 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) CrgA PF06781.12 EMT51606.1 - 0.0021 18.1 0.1 0.0031 17.5 0.1 1.3 1 0 0 1 1 1 1 Cell division protein CrgA Trep_Strep PF09605.10 EMT51606.1 - 0.0086 16.1 0.0 0.0092 16.0 0.0 1.0 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) Trp_oprn_chp PF09534.10 EMT51606.1 - 0.01 15.6 0.2 0.013 15.4 0.2 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4366 PF14283.6 EMT51606.1 - 0.027 14.5 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) UL45 PF05473.12 EMT51606.1 - 0.078 12.6 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like SNARE PF05739.19 EMT51606.1 - 0.087 12.8 0.1 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 SNARE domain HTH_Crp_2 PF13545.6 EMT51608.1 - 1.3e-10 41.0 0.1 1.5e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 EMT51608.1 - 0.0074 16.4 0.2 0.013 15.6 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 EMT51608.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.4 1 1 0 1 1 1 0 Winged helix-turn helix SgrR_N PF12793.7 EMT51608.1 - 0.045 14.0 0.0 0.057 13.6 0.0 1.1 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term MarR PF01047.22 EMT51608.1 - 0.094 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 MarR family DUF2935 PF11155.8 EMT51609.1 - 1.9e-54 183.2 18.2 1e-28 100.1 6.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF2935) KAP_NTPase PF07693.14 EMT51609.1 - 0.023 14.0 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Oxidored_molyb PF00174.19 EMT51610.1 - 6.5e-35 120.3 0.1 8.4e-35 119.9 0.1 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain CoA_binding_2 PF13380.6 EMT51611.1 - 1.1e-36 125.8 0.3 1.2e-36 125.7 0.3 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 EMT51611.1 - 0.011 16.5 0.6 0.015 16.0 0.2 1.5 2 0 0 2 2 2 0 CoA binding domain DUF4304 PF14137.6 EMT51611.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4304) Peptidase_M17 PF00883.21 EMT51612.1 - 2.8e-116 388.2 1.4 4.1e-116 387.6 1.4 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EMT51612.1 - 2.4e-17 63.0 0.2 4.8e-17 62.0 0.2 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DUF309 PF03745.14 EMT51613.1 - 3.4e-23 81.1 0.2 4.6e-23 80.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF309) Xin PF08043.12 EMT51613.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Xin repeat DUF212 PF02681.14 EMT51614.1 - 6.4e-50 168.6 0.5 7.4e-50 168.4 0.5 1.0 1 0 0 1 1 1 1 Divergent PAP2 family ApoL PF05461.11 EMT51614.1 - 1.6 8.0 3.4 1.7 7.9 0.1 2.0 1 1 0 2 2 2 0 Apolipoprotein L Peripla_BP_2 PF01497.18 EMT51615.1 - 8.6e-28 97.5 0.0 1e-27 97.2 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein 3D PF06725.11 EMT51616.1 - 4.2e-19 68.5 0.2 6.7e-19 67.9 0.2 1.3 1 0 0 1 1 1 1 3D domain YuiB PF14068.6 EMT51617.1 - 2.3e-19 69.9 14.4 2.7e-09 37.5 9.2 2.0 1 1 1 2 2 2 2 Putative membrane protein Bacteriocin_IIc PF10439.9 EMT51617.1 - 0.0027 17.8 1.9 0.0027 17.8 1.9 2.0 2 0 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide SPC12 PF06645.13 EMT51617.1 - 0.35 11.0 8.5 2.2 8.4 5.2 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF1700 PF08006.11 EMT51617.1 - 1.6 8.2 8.1 1.8 8.1 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) RseC_MucC PF04246.12 EMT51617.1 - 3.3 7.7 6.5 2.1 8.3 0.6 2.0 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4407 PF14362.6 EMT51617.1 - 6.9 5.9 5.8 10 5.4 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5351 PF17302.2 EMT51618.1 - 8.6e-15 54.6 9.9 1e-14 54.4 9.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5351) DnaJ_CXXCXGXG PF00684.19 EMT51618.1 - 0.0002 21.6 5.4 0.0015 18.8 5.4 1.8 1 1 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EMT51618.1 - 0.0023 17.9 4.4 0.004 17.1 4.4 1.5 1 1 0 1 1 1 1 Tryptophan RNA-binding attenuator protein inhibitory protein PADR1 PF08063.12 EMT51618.1 - 0.59 10.0 7.1 2.7 7.9 1.0 2.1 1 1 1 2 2 2 0 PADR1 (NUC008) domain NUDIX PF00293.28 EMT51619.1 - 2e-20 73.2 0.2 2.9e-20 72.7 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EMT51619.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.4 1 1 0 1 1 1 0 NUDIX domain Pyr_redox_2 PF07992.14 EMT51621.1 - 2.6e-48 164.7 0.0 3.1e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMT51621.1 - 9e-08 32.6 0.0 1.6e-06 28.5 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMT51621.1 - 5.1e-05 23.3 0.2 1.1 9.3 0.0 3.4 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 EMT51621.1 - 0.00037 20.2 0.1 0.36 10.3 0.0 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMT51621.1 - 0.14 11.0 0.0 0.41 9.4 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 EMT51622.1 - 9e-34 117.0 0.1 1.1e-33 116.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT51622.1 - 1.1e-28 100.5 1.6 5.3e-26 91.6 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMT51622.1 - 2.4e-16 60.1 0.5 1.3e-11 44.8 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT51622.1 - 9.5e-12 44.3 0.4 1.7e-05 23.8 0.1 3.4 5 0 0 5 5 5 2 HI0933-like protein K_oxygenase PF13434.6 EMT51622.1 - 3e-08 33.2 0.3 1.4e-05 24.4 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EMT51622.1 - 6.1e-06 26.1 1.4 0.017 14.7 0.1 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMT51622.1 - 2.3e-05 24.5 0.1 8.9e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMT51622.1 - 0.00038 19.9 0.0 0.00066 19.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMT51622.1 - 0.0031 16.8 0.1 0.013 14.8 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EMT51622.1 - 0.0054 15.9 0.1 0.37 9.8 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EMT51622.1 - 0.042 12.9 0.4 0.59 9.1 0.0 2.4 2 1 1 3 3 3 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EMT51622.1 - 0.051 12.8 0.2 0.16 11.2 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 EMT51622.1 - 0.09 11.8 3.3 8.6 5.3 0.1 3.3 3 1 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EMT51622.1 - 0.2 11.7 0.3 22 5.0 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding TF_Zn_Ribbon PF08271.12 EMT51623.1 - 0.016 14.7 2.5 1.7 8.3 0.0 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding zf-C3HC4_3 PF13920.6 EMT51623.1 - 0.017 15.0 8.1 0.98 9.3 0.4 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.15 EMT51623.1 - 0.026 14.1 4.7 0.041 13.4 1.1 2.1 2 0 0 2 2 2 0 RecR protein zinc-ribbons_6 PF07191.12 EMT51623.1 - 0.028 14.4 2.7 0.33 11.0 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbons PADR1 PF08063.12 EMT51623.1 - 0.15 11.8 3.8 15 5.4 0.1 3.0 2 1 1 3 3 3 0 PADR1 (NUC008) domain Rad50_zn_hook PF04423.14 EMT51623.1 - 0.17 11.8 0.6 0.17 11.8 0.6 2.6 2 1 1 3 3 3 0 Rad50 zinc hook motif DZR PF12773.7 EMT51623.1 - 0.21 11.6 4.2 2.7 8.1 4.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon Redoxin PF08534.10 EMT51623.1 - 0.32 10.7 1.4 0.54 10.0 0.0 1.9 2 1 0 2 2 2 0 Redoxin zf-RING_4 PF14570.6 EMT51623.1 - 0.4 10.5 4.9 15 5.5 0.1 3.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EMT51623.1 - 1.5 8.8 11.5 0.56 10.1 2.9 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 DUF3090 PF11290.8 EMT51623.1 - 1.9 8.3 3.6 0.76 9.6 0.8 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3090) zf-FPG_IleRS PF06827.14 EMT51623.1 - 4.1 7.3 8.5 27 4.7 0.3 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-C4_Topoisom PF01396.19 EMT51623.1 - 4.4 7.2 8.6 6.7 6.6 0.2 3.1 2 1 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DUF1272 PF06906.11 EMT51623.1 - 5.7 7.1 9.2 24 5.1 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1272) HATPase_c PF02518.26 EMT51624.1 - 2.1e-13 50.8 0.0 4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 EMT51624.1 - 2.6e-12 46.9 0.3 5.1e-12 46.0 0.3 1.5 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 EMT51624.1 - 1.7e-08 34.4 0.0 5.9e-08 32.6 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 EMT51624.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 EMT51624.1 - 0.0033 17.4 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Response_reg PF00072.24 EMT51625.1 - 4.7e-24 84.7 0.0 8.4e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT51625.1 - 6e-22 77.5 0.2 1.3e-21 76.5 0.2 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal OKR_DC_1_N PF03709.15 EMT51625.1 - 0.16 12.2 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF4194 PF13835.6 EMT51626.1 - 0.019 14.7 0.1 0.028 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) Chalcone_3 PF16036.5 EMT51626.1 - 0.048 13.8 1.5 0.061 13.4 1.5 1.2 1 0 0 1 1 1 0 Chalcone isomerase-like DUF4363 PF14276.6 EMT51626.1 - 0.064 13.4 3.3 0.12 12.5 3.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) Spt5_N PF11942.8 EMT51626.1 - 7.3 7.6 10.9 39 5.3 10.9 2.1 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Fibrillarin PF01269.17 EMT51627.1 - 0.074 12.2 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin ketoacyl-synt PF00109.26 EMT51628.1 - 2.7e-66 223.8 2.3 2.7e-66 223.8 2.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMT51628.1 - 3.8e-36 123.7 3.1 1.3e-35 122.0 1.6 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EMT51628.1 - 2.8e-05 23.6 3.1 0.00073 19.0 0.7 2.7 2 1 1 3 3 3 2 Thiolase, N-terminal domain MLTR_LBD PF17765.1 EMT51629.1 - 3.5e-39 134.6 0.0 5.1e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 EMT51629.1 - 2.2e-18 66.3 2.3 6.7e-18 64.8 2.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EMT51629.1 - 0.00026 21.0 0.1 0.00072 19.6 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix HTH_26 PF13443.6 EMT51629.1 - 0.054 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Sel_put PF04328.13 EMT51629.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Selenoprotein, putative PepSY PF03413.19 EMT51630.1 - 1.4e-06 28.8 3.7 0.057 14.0 0.1 5.2 4 1 0 4 4 4 3 Peptidase propeptide and YPEB domain Sigma70_r2 PF04542.14 EMT51631.1 - 3e-20 71.7 0.8 4.4e-20 71.2 0.8 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT51631.1 - 5.6e-14 51.6 0.6 1.5e-13 50.2 0.6 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT51631.1 - 2e-05 24.0 0.0 8.7e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT51631.1 - 2.4e-05 24.3 0.1 4e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 ECF sigma factor HTH_28 PF13518.6 EMT51631.1 - 0.031 14.4 0.4 0.12 12.5 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain GerE PF00196.19 EMT51631.1 - 0.15 11.6 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family YPEB PF14620.6 EMT51632.1 - 0.00037 19.9 1.2 0.00044 19.7 0.0 1.7 2 0 0 2 2 2 1 YpeB sporulation DUF4901 PF16244.5 EMT51632.1 - 0.0016 17.8 0.0 0.0059 16.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4901) FTP PF07504.13 EMT51632.1 - 0.029 14.2 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Fungalysin/Thermolysin Propeptide Motif Spc29 PF17082.5 EMT51632.1 - 0.092 12.6 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Spindle Pole Component 29 Peptidase_M20 PF01546.28 EMT51633.1 - 7.9e-11 42.0 0.0 3.7e-10 39.8 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT51633.1 - 0.015 15.2 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Peptidase dimerisation domain IclR PF01614.18 EMT51634.1 - 7.4e-21 74.3 0.0 1.3e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EMT51634.1 - 3.5e-12 45.9 0.0 7.4e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain Rrf2 PF02082.20 EMT51634.1 - 0.00067 20.0 0.0 0.0018 18.6 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 EMT51634.1 - 0.0078 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 EMT51634.1 - 0.041 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 EMT51634.1 - 0.048 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EMT51634.1 - 0.078 13.1 0.0 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 EMT51634.1 - 0.099 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_9 PF08221.11 EMT51634.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain PA26 PF04636.13 EMT51634.1 - 0.23 10.3 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) BPD_transp_1 PF00528.22 EMT51635.1 - 7.5e-25 87.7 7.3 1.1e-24 87.2 7.3 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_3 PF00497.20 EMT51636.1 - 2.6e-67 226.6 0.7 3e-67 226.4 0.7 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EMT51636.1 - 4.4e-07 30.1 0.0 1.3e-06 28.6 0.0 1.8 1 1 1 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 EMT51636.1 - 5.1e-06 26.6 0.1 8.3e-06 25.9 0.1 1.4 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 EMT51636.1 - 0.0027 17.2 0.2 0.0039 16.6 0.2 1.1 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 EMT51636.1 - 0.0081 15.8 0.3 0.015 14.9 0.3 1.6 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF1565 PF07602.11 EMT51636.1 - 0.035 13.5 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) Av_adeno_fibre PF06536.11 EMT51636.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Avian adenovirus fibre, N-terminal ABC_tran PF00005.27 EMT51637.1 - 2.5e-37 128.5 0.0 3.4e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT51637.1 - 1.5e-14 54.5 0.0 1.7e-07 31.4 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51637.1 - 1.9e-10 40.6 0.0 7.2e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 EMT51637.1 - 8e-05 21.5 0.0 0.019 13.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EMT51637.1 - 0.0002 21.0 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EMT51637.1 - 0.00054 18.9 0.2 0.42 9.3 0.0 3.0 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 EMT51637.1 - 0.00071 20.0 0.1 0.00094 19.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EMT51637.1 - 0.00078 20.0 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT51637.1 - 0.0014 18.5 0.1 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 EMT51637.1 - 0.0019 18.0 0.0 0.28 10.9 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 EMT51637.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 EMT51637.1 - 0.012 15.8 0.2 0.078 13.2 0.0 2.2 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EMT51637.1 - 0.012 15.0 0.2 0.048 13.0 0.0 2.0 2 1 1 3 3 3 0 FtsK/SpoIIIE family AAA_33 PF13671.6 EMT51637.1 - 0.016 15.4 0.2 0.034 14.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EMT51637.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EMT51637.1 - 0.03 14.2 0.0 0.23 11.4 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EMT51637.1 - 0.032 13.8 0.1 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMT51637.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EMT51637.1 - 0.04 13.8 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EMT51637.1 - 0.043 13.0 0.1 1.2 8.3 0.0 2.6 2 1 1 3 3 3 0 NB-ARC domain SbcCD_C PF13558.6 EMT51637.1 - 0.082 13.1 0.1 0.87 9.9 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit CPT PF07931.12 EMT51637.1 - 0.1 12.4 0.1 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 EMT51637.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EMT51637.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cupredoxin_1 PF13473.6 EMT51638.1 - 2.3e-10 40.5 0.0 3.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 EMT51638.1 - 0.0098 16.3 0.7 0.51 10.8 0.7 2.4 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family MLTD_N PF06474.12 EMT51638.1 - 0.34 11.1 3.0 0.54 10.5 3.0 1.3 1 0 0 1 1 1 0 MltD lipid attachment motif LPAM_2 PF13627.6 EMT51638.1 - 0.51 10.3 3.5 0.78 9.7 3.5 1.3 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site YolD PF08863.10 EMT51639.1 - 0.00021 21.3 0.0 0.00032 20.7 0.0 1.2 1 0 0 1 1 1 1 YolD-like protein Sigma70_r2 PF04542.14 EMT51640.1 - 9.8e-20 70.1 1.2 1.7e-19 69.3 1.2 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT51640.1 - 4.5e-15 55.1 0.0 8.2e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT51640.1 - 2.4e-10 39.8 0.2 5.1e-10 38.7 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 EMT51640.1 - 0.0053 16.9 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.19 EMT51640.1 - 0.014 14.9 0.0 0.043 13.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_17 PF12728.7 EMT51640.1 - 0.022 14.9 1.5 0.042 14.0 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 EMT51640.1 - 0.087 12.6 0.3 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain Phage_antitermQ PF06530.12 EMT51640.1 - 0.091 12.7 0.1 0.24 11.3 0.0 1.7 2 1 0 2 2 2 0 Phage antitermination protein Q HTH_AsnC-type PF13404.6 EMT51640.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain PSK_trans_fac PF07704.11 EMT51641.1 - 8.1 7.3 6.5 0.92 10.3 1.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor MFS_1 PF07690.16 EMT51643.1 - 0.007 15.3 1.7 0.0078 15.2 1.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Fe-S_biosyn PF01521.20 EMT51644.1 - 1.2e-20 73.7 0.0 1.4e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SpoOE-like PF09388.10 EMT51645.1 - 5.3e-10 39.0 0.8 8.3e-10 38.4 0.8 1.4 1 0 0 1 1 1 1 Spo0E like sporulation regulatory protein Radical_SAM PF04055.21 EMT51646.1 - 7.2e-16 59.0 0.3 9.9e-16 58.6 0.3 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EMT51646.1 - 0.013 15.7 0.0 0.03 14.4 0.0 1.7 1 1 0 1 1 1 0 4Fe-4S single cluster domain Fer4_12 PF13353.6 EMT51646.1 - 0.043 14.1 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain MFS_1 PF07690.16 EMT51647.1 - 1.9e-18 66.5 47.3 6.1e-17 61.6 33.3 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_3 PF05977.13 EMT51647.1 - 0.97 7.8 23.9 0.083 11.3 17.7 1.7 1 1 0 2 2 2 0 Transmembrane secretion effector DUF1450 PF07293.11 EMT51648.1 - 3.5e-33 113.2 0.2 4.3e-33 112.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1450) 2Fe-2S_thioredx PF01257.19 EMT51648.1 - 0.015 15.1 0.1 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Pyr_redox_2 PF07992.14 EMT51649.1 - 2.5e-35 122.1 0.0 3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMT51649.1 - 3.2e-08 34.0 0.1 1.3e-06 28.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMT51649.1 - 2.2e-06 27.7 0.0 0.089 12.8 0.0 3.2 2 1 1 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMT51649.1 - 9.5e-06 25.1 0.0 1.5e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMT51649.1 - 0.00019 20.6 0.0 0.00078 18.6 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 EMT51649.1 - 0.0004 19.6 0.0 0.00093 18.4 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EMT51649.1 - 0.0009 19.4 0.0 0.021 15.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMT51649.1 - 0.027 14.0 0.8 3.6 7.1 0.1 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase Spo12 PF05032.12 EMT51649.1 - 0.14 12.0 0.1 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Spo12 family TetR_N PF00440.23 EMT51651.1 - 1.9e-05 24.4 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EMT51651.1 - 0.00015 22.0 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 EMT51651.1 - 0.0018 18.3 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Pec_lyase_N PF04431.13 EMT51652.1 - 0.12 12.7 0.2 0.61 10.4 0.0 2.2 2 0 0 2 2 2 0 Pectate lyase, N terminus ATPase_gene1 PF09527.10 EMT51652.1 - 1.3 9.3 9.7 65 3.8 9.7 2.3 1 1 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Glyco_transf_90 PF05686.12 EMT51653.1 - 0.016 14.2 0.1 0.017 14.0 0.1 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 90 TIMP PF00965.17 EMT51654.1 - 0.0077 16.1 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase DUF805 PF05656.14 EMT51655.1 - 0.0077 16.6 4.9 0.015 15.7 4.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF805) DUF2070 PF09843.9 EMT51655.1 - 0.13 10.5 2.4 0.13 10.5 2.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Fungus-induced PF10917.8 EMT51655.1 - 0.22 11.9 0.5 7 7.1 0.0 2.3 2 0 0 2 2 2 0 Fungus-induced protein TMEM251 PF15190.6 EMT51655.1 - 3.1 7.8 7.6 0.21 11.6 1.6 1.9 1 1 1 2 2 2 0 Transmembrane protein 251 DinB_2 PF12867.7 EMT51656.1 - 5.9e-17 62.4 1.6 6.7e-17 62.2 1.6 1.0 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 EMT51656.1 - 3.6e-05 24.2 0.4 0.00022 21.6 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF664) DinB PF05163.12 EMT51656.1 - 0.00015 21.8 0.3 0.0002 21.3 0.3 1.1 1 0 0 1 1 1 1 DinB family Sld5 PF05916.11 EMT51656.1 - 0.01 16.3 0.1 0.017 15.6 0.1 1.4 1 1 0 1 1 1 0 GINS complex protein MDMPI_N PF11716.8 EMT51656.1 - 0.029 15.1 0.0 0.048 14.3 0.0 1.4 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF1572 PF07609.11 EMT51656.1 - 0.074 12.8 0.0 0.35 10.7 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1572) IFP_35_N PF07334.13 EMT51657.1 - 0.079 13.0 0.8 0.13 12.3 0.8 1.3 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus VCBS PF13517.6 EMT51658.1 - 0.00045 20.7 5.5 0.064 13.9 2.1 3.0 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EMT51658.1 - 0.13 12.4 3.0 7.8 6.7 0.3 3.3 3 0 0 3 3 3 0 FG-GAP repeat DUF1462 PF07315.11 EMT51660.1 - 2.6e-39 133.4 0.0 3.1e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1462) Cys_Met_Meta_PP PF01053.20 EMT51661.1 - 5.6e-159 528.8 0.0 6.3e-159 528.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EMT51661.1 - 3.3e-11 43.1 0.2 1.2e-10 41.2 0.2 2.1 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EMT51661.1 - 9.9e-10 38.1 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMT51661.1 - 1.4e-06 27.6 0.0 2.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 EMT51661.1 - 0.00083 18.3 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EMT51661.1 - 0.0051 16.1 0.0 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EMT51661.1 - 0.0052 15.4 0.0 0.0074 14.9 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase PALP PF00291.25 EMT51662.1 - 3.6e-68 230.1 0.3 4.4e-68 229.8 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thi4 PF01946.17 EMT51662.1 - 0.0013 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Abhydrolase_3 PF07859.13 EMT51662.1 - 0.12 12.3 0.3 2.4 7.9 0.1 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold NifU PF01106.17 EMT51663.1 - 4.4e-30 103.6 0.3 4.9e-30 103.5 0.3 1.0 1 0 0 1 1 1 1 NifU-like domain Abhydrolase_1 PF00561.20 EMT51664.1 - 7e-16 58.6 0.0 1.7e-11 44.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMT51664.1 - 7.6e-15 54.8 0.0 4.1e-09 36.1 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMT51664.1 - 2.5e-11 44.6 1.2 2.2e-10 41.5 1.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EMT51664.1 - 6.4e-11 42.1 0.0 1.4e-10 41.0 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EMT51664.1 - 1.9e-10 40.8 0.0 3.7e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 EMT51664.1 - 9.9e-08 31.9 0.0 2.5e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EMT51664.1 - 7.2e-07 29.2 0.0 0.05 13.4 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase DLH PF01738.18 EMT51664.1 - 1.7e-05 24.5 0.0 0.00013 21.6 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EMT51664.1 - 0.00013 22.0 0.1 0.0013 18.7 0.1 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 EMT51664.1 - 0.00026 19.8 0.0 0.0048 15.6 0.0 2.2 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.10 EMT51664.1 - 0.001 19.2 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein LIP PF03583.14 EMT51664.1 - 0.095 12.0 0.0 12 5.2 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase 2-Hacid_dh_C PF02826.19 EMT51665.1 - 5.5e-64 214.8 0.0 1.8e-63 213.1 0.0 1.9 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMT51665.1 - 3.2e-35 120.7 0.1 3.8e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMT51665.1 - 1.1e-06 28.9 0.1 2.8e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EMT51665.1 - 1.2e-05 24.9 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 EMT51665.1 - 0.0024 18.4 0.1 0.0099 16.4 0.0 2.1 2 1 0 2 2 2 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 EMT51665.1 - 0.0024 17.2 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 EMT51665.1 - 0.0049 17.4 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_16 PF00722.21 EMT51666.1 - 0.016 14.7 0.1 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 PgpA PF04608.13 EMT51667.1 - 1.1e-16 61.1 0.0 1.3e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylglycerophosphatase A DUF826 PF05696.11 EMT51667.1 - 0.032 14.3 0.7 1.8 8.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF826) Hydrolase_6 PF13344.6 EMT51668.1 - 4.1e-27 94.2 0.0 7.4e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMT51668.1 - 6.2e-18 64.6 0.0 1.8e-17 63.2 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EMT51668.1 - 1.8e-10 41.5 1.7 1e-09 39.0 1.7 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMT51668.1 - 2.5e-10 40.7 0.1 9.5e-08 32.3 0.0 2.8 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase HTH_DeoR PF08220.12 EMT51669.1 - 1.5e-07 31.1 1.9 2.2e-07 30.5 0.3 2.0 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_5 PF01022.20 EMT51669.1 - 3.9e-07 29.8 4.2 5.2e-07 29.4 0.2 2.8 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 EMT51669.1 - 8.4e-07 28.5 0.1 1.8e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EMT51669.1 - 9e-06 25.7 0.1 2.1e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 EMT51669.1 - 2.5e-05 24.1 0.2 6e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 EMT51669.1 - 4.4e-05 23.3 0.2 8.1e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 MarR family V4R PF02830.18 EMT51669.1 - 0.0001 22.2 1.6 0.00018 21.5 1.6 1.5 1 0 0 1 1 1 1 V4R domain MetOD1 PF18546.1 EMT51669.1 - 0.00034 20.6 0.2 0.00052 20.0 0.2 1.4 1 0 0 1 1 1 1 Metanogen output domain 1 FaeA PF04703.12 EMT51669.1 - 0.00089 19.6 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 FaeA-like protein HTH_12 PF08461.10 EMT51669.1 - 0.0011 18.8 0.8 0.026 14.5 0.0 2.5 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain TFIIE_alpha PF02002.17 EMT51669.1 - 0.0021 17.9 0.1 0.0045 16.8 0.1 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_29 PF13551.6 EMT51669.1 - 0.0026 17.8 0.0 0.0069 16.4 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix PadR PF03551.14 EMT51669.1 - 0.0066 16.4 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_AsnC-type PF13404.6 EMT51669.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain GntR PF00392.21 EMT51669.1 - 0.018 14.7 0.1 0.039 13.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 EMT51669.1 - 0.02 14.8 0.2 0.052 13.5 0.2 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 EMT51669.1 - 0.024 14.5 0.1 0.059 13.3 0.1 1.6 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.10 EMT51669.1 - 0.026 14.3 0.1 0.062 13.1 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Rrf2 PF02082.20 EMT51669.1 - 0.053 13.9 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator Sigma70_r4_2 PF08281.12 EMT51669.1 - 0.082 12.6 0.1 0.72 9.6 0.0 2.4 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_34 PF13601.6 EMT51669.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_9 PF08221.11 EMT51669.1 - 0.16 12.1 0.2 0.32 11.1 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF86 PF01934.17 EMT51670.1 - 1.7e-20 73.1 0.1 2e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF86 FBPase_glpX PF03320.13 EMT51671.1 - 3.1e-138 459.8 10.2 3.5e-138 459.7 10.2 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded DUF3055 PF11256.8 EMT51672.1 - 6.6e-38 128.8 0.7 7.6e-38 128.7 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3055) CesT PF05932.13 EMT51672.1 - 0.1 12.8 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family SDF PF00375.18 EMT51673.1 - 1.9e-80 270.8 43.3 2.1e-80 270.6 43.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4499 PF14934.6 EMT51673.1 - 0.012 15.9 1.5 0.14 12.5 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4499) DUF5453 PF17534.2 EMT51673.1 - 0.81 9.6 5.4 0.096 12.6 0.7 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5453) Nitroreductase PF00881.24 EMT51674.1 - 1.1e-12 48.3 0.1 1.3e-12 48.1 0.1 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EMT51674.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative TM nitroreductase rve_2 PF13333.6 EMT51677.1 - 5.3e-15 55.3 0.6 8.4e-15 54.7 0.6 1.3 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 EMT51677.1 - 1.1e-13 51.4 0.0 1.5e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EMT51677.1 - 2.5e-13 49.6 0.0 3.6e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Transposase_mut PF00872.18 EMT51678.1 - 1.8e-31 109.4 0.3 1.9e-31 109.3 0.3 1.0 1 0 0 1 1 1 1 Transposase, Mutator family SRP68 PF16969.5 EMT51678.1 - 0.017 14.1 0.1 0.017 14.1 0.1 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 Ish1 PF10281.9 EMT51678.1 - 0.1 12.9 0.1 0.4 11.0 0.1 2.2 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein TssO PF17561.2 EMT51678.1 - 0.13 12.4 3.7 0.1 12.7 2.0 1.6 2 0 0 2 2 2 0 Type VI secretion system, TssO HTH_23 PF13384.6 EMT51678.1 - 0.21 11.4 0.3 1.9 8.4 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain Linker_histone PF00538.19 EMT51678.1 - 0.31 11.4 1.7 3.4 8.1 0.1 2.6 3 0 0 3 3 3 0 linker histone H1 and H5 family HTH_3 PF01381.22 EMT51679.1 - 2.6e-12 46.6 0.1 6.5e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EMT51679.1 - 7.4e-08 32.3 0.3 3.9e-07 30.0 0.0 2.4 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_31 PF13560.6 EMT51679.1 - 6.3e-07 29.6 0.0 1.4e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain TPR_8 PF13181.6 EMT51679.1 - 1e-05 25.3 3.4 0.033 14.4 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMT51679.1 - 1.3e-05 24.8 3.6 0.074 12.9 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat HTH_25 PF13413.6 EMT51679.1 - 2.4e-05 24.1 0.2 0.00059 19.6 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain TPR_12 PF13424.6 EMT51679.1 - 4.4e-05 23.7 0.3 0.0082 16.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMT51679.1 - 5.1e-05 23.1 2.6 0.052 13.7 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat HTH_26 PF13443.6 EMT51679.1 - 0.00069 20.0 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain TPR_7 PF13176.6 EMT51679.1 - 0.00077 19.3 0.4 0.0084 16.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EMT51679.1 - 0.0036 17.1 0.1 0.12 12.3 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 EMT51679.1 - 0.0059 16.3 4.0 0.12 12.1 1.2 2.5 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TPR_14 PF13428.6 EMT51679.1 - 0.044 14.6 0.0 1.7 9.6 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 EMT51679.1 - 0.13 12.1 8.3 0.22 11.4 0.1 3.6 2 1 1 3 3 3 0 Region in Clathrin and VPS LrgB PF04172.16 EMT51680.1 - 3.6e-55 186.8 13.9 4.1e-55 186.6 13.9 1.0 1 0 0 1 1 1 1 LrgB-like family TMEM239 PF15841.5 EMT51680.1 - 0.058 13.3 2.0 0.077 12.9 1.2 1.6 1 1 0 1 1 1 0 Transmembrane protein 239 family DUF3042 PF11240.8 EMT51680.1 - 3.2 7.9 4.4 1 9.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) LrgA PF03788.14 EMT51681.1 - 6.4e-23 80.5 10.5 8.8e-23 80.1 10.5 1.2 1 0 0 1 1 1 1 LrgA family DUF4689 PF15755.5 EMT51681.1 - 0.023 14.3 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) LysR_substrate PF03466.20 EMT51682.1 - 5.4e-51 172.9 1.1 6.7e-51 172.6 1.1 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT51682.1 - 3e-22 78.3 0.1 6.1e-22 77.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 EMT51682.1 - 0.0096 15.1 0.0 0.55 9.3 0.0 2.4 2 1 0 2 2 2 2 PBP superfamily domain Fe_dep_repress PF01325.19 EMT51682.1 - 0.019 15.1 1.0 0.038 14.2 0.2 1.9 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 EMT51682.1 - 0.18 11.8 0.3 0.48 10.4 0.1 1.8 2 0 0 2 2 2 0 MarR family DrsE PF02635.15 EMT51683.1 - 7e-06 26.4 0.1 8.2e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 DsrE/DsrF-like family Peptidase_M20 PF01546.28 EMT51684.1 - 4.6e-33 114.7 0.0 6.1e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EMT51684.1 - 6.6e-06 25.9 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 EMT51684.1 - 0.0038 17.1 0.0 0.7 9.8 0.0 2.4 2 1 0 2 2 2 2 Peptidase dimerisation domain ABC_tran PF00005.27 EMT51685.1 - 8.4e-31 107.3 0.1 1.2e-30 106.8 0.1 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT51685.1 - 2e-19 69.8 0.0 3.7e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT51685.1 - 2.9e-08 33.9 0.0 9.1e-08 32.3 0.0 1.7 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51685.1 - 2.8e-07 30.2 0.1 4.5e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT51685.1 - 5.6e-05 23.4 0.3 0.00072 19.9 0.3 2.1 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 EMT51685.1 - 0.0019 17.6 0.2 0.12 11.7 0.1 2.2 2 0 0 2 2 2 1 Bacterial TniB protein DUF87 PF01935.17 EMT51685.1 - 0.0022 18.1 0.2 0.005 17.0 0.2 1.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA PF00004.29 EMT51685.1 - 0.0023 18.4 0.3 0.11 12.9 0.3 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EMT51685.1 - 0.0044 16.8 0.0 0.53 9.9 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EMT51685.1 - 0.014 15.1 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EMT51685.1 - 0.018 14.4 0.1 0.081 12.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EMT51685.1 - 0.044 13.3 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EMT51685.1 - 0.11 12.9 0.1 0.15 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 EMT51685.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.7 EMT51685.1 - 0.14 11.1 0.3 0.51 9.2 0.0 1.9 2 1 0 2 2 2 0 AAA-like domain Pox_A32 PF04665.12 EMT51685.1 - 0.15 11.5 0.1 0.61 9.5 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.6 EMT51685.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain Myosin_head PF00063.21 EMT51685.1 - 0.2 9.8 0.0 0.26 9.5 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) BPD_transp_1 PF00528.22 EMT51686.1 - 4e-29 101.7 15.9 4e-29 101.7 15.9 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT51686.1 - 4.9e-13 48.8 0.2 4.9e-13 48.8 0.2 3.9 5 0 0 5 5 5 1 N-terminal TM domain of oligopeptide transport permease C DUF872 PF05915.12 EMT51686.1 - 1.3 9.2 0.0 1.3 9.2 0.0 2.9 3 2 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) EI24 PF07264.11 EMT51686.1 - 1.7 8.9 13.8 1.1 9.5 10.9 2.0 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) BPD_transp_1 PF00528.22 EMT51687.1 - 3e-37 128.2 16.4 3e-37 128.2 16.4 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component MARVEL PF01284.23 EMT51687.1 - 1.1 9.3 12.5 1.3 9.1 4.0 2.8 3 1 0 3 3 3 0 Membrane-associating domain SBP_bac_5 PF00496.22 EMT51688.1 - 9.8e-78 261.7 10.5 1.2e-77 261.4 10.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle ROK PF00480.20 EMT51689.1 - 1.4e-53 182.3 3.0 1.8e-53 182.0 3.0 1.1 1 0 0 1 1 1 1 ROK family HTH_24 PF13412.6 EMT51689.1 - 1.1e-07 31.3 0.1 2.7e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 EMT51689.1 - 0.00037 20.3 0.1 0.00071 19.5 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 EMT51689.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 EMT51689.1 - 0.0013 18.7 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_27 PF13463.6 EMT51689.1 - 0.0031 18.0 0.0 0.0071 16.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 EMT51689.1 - 0.0055 16.9 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 EMT51689.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 MarR family SMC_ScpB PF04079.16 EMT51689.1 - 0.025 14.2 0.2 0.043 13.4 0.2 1.4 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB HTH_11 PF08279.12 EMT51689.1 - 0.046 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 HTH domain HRDC PF00570.23 EMT51689.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 HRDC domain Hexokinase_2 PF03727.16 EMT51689.1 - 0.088 12.2 1.4 0.11 11.9 0.1 1.9 3 0 0 3 3 3 0 Hexokinase RPA_C PF08784.11 EMT51689.1 - 0.1 13.2 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 Replication protein A C terminal HTS PF04204.16 EMT51690.1 - 2e-142 473.5 0.0 2.3e-142 473.3 0.0 1.0 1 0 0 1 1 1 1 Homoserine O-succinyltransferase DUF903 PF06004.12 EMT51690.1 - 0.0021 17.9 0.1 0.0042 16.9 0.0 1.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF903) MFS_1 PF07690.16 EMT51691.1 - 1.6e-16 60.2 27.1 5.1e-16 58.5 22.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT51691.1 - 1.2 7.9 11.8 0.42 9.4 9.4 1.5 2 0 0 2 2 2 0 MFS_1 like family MFS_1 PF07690.16 EMT51692.1 - 5.7e-33 114.3 26.1 8.2e-33 113.8 26.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2976 PF11190.8 EMT51692.1 - 0.26 11.1 8.5 0.089 12.6 1.7 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF2976) MFS_3 PF05977.13 EMT51692.1 - 0.55 8.6 11.2 0.68 8.2 11.2 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector MFS_1 PF07690.16 EMT51695.1 - 1.3e-15 57.2 30.3 4.8e-10 38.9 18.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT51695.1 - 0.04 12.3 0.0 0.04 12.3 0.0 3.1 2 1 0 3 3 3 0 Transmembrane secretion effector HTH_18 PF12833.7 EMT51696.1 - 7.1e-20 71.1 0.0 1.2e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Cass2 PF14526.6 EMT51696.1 - 5.7e-15 55.8 0.9 1e-14 55.0 0.9 1.5 1 0 0 1 1 1 1 Integron-associated effector binding protein GyrI-like PF06445.15 EMT51696.1 - 3.8e-13 50.0 1.7 5.5e-13 49.5 1.7 1.3 1 0 0 1 1 1 1 GyrI-like small molecule binding domain HTH_AraC PF00165.23 EMT51696.1 - 4.9e-12 45.6 0.0 5.4e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family N_Asn_amidohyd PF14736.6 EMT51696.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase CybS PF05328.12 EMT51696.1 - 0.13 11.9 1.0 0.45 10.2 0.3 2.1 2 0 0 2 2 2 0 CybS, succinate dehydrogenase cytochrome B small subunit Amidohydro_3 PF07969.11 EMT51697.1 - 4.3e-52 178.1 0.2 5.8e-51 174.4 0.2 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EMT51697.1 - 1.1e-19 70.9 0.0 1.5e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family RP-C PF03428.13 EMT51697.1 - 0.0021 17.7 0.1 0.0036 17.0 0.1 1.3 1 0 0 1 1 1 1 Replication protein C N-terminal domain Transp_cyt_pur PF02133.15 EMT51698.1 - 9.1e-53 179.6 46.6 1.2e-52 179.2 46.6 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2101 PF09874.9 EMT51698.1 - 8 6.1 8.6 0.15 11.8 1.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) NAPRTase_N PF17767.1 EMT51699.1 - 6.6e-38 129.9 1.1 3.2e-37 127.7 0.2 2.4 3 0 0 3 3 3 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 EMT51699.1 - 7.9e-30 103.5 0.2 1.4e-29 102.8 0.2 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 EMT51699.1 - 2.3e-09 37.2 0.0 3.5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Peptidase_M24 PF00557.24 EMT51700.1 - 4.4e-56 189.9 0.4 5e-56 189.7 0.4 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 ATP-cone PF03477.16 EMT51700.1 - 0.0088 16.6 0.0 0.033 14.8 0.0 1.8 2 0 0 2 2 2 1 ATP cone domain DUF3215 PF11503.8 EMT51700.1 - 0.011 15.5 0.1 0.042 13.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) PerC PF06069.11 EMT51700.1 - 0.072 13.4 0.0 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 PerC transcriptional activator TetR_N PF00440.23 EMT51701.1 - 8.9e-08 31.8 0.1 1.5e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family LacI PF00356.21 EMT51701.1 - 0.059 13.2 0.1 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family EutH PF04346.12 EMT51702.1 - 3e-121 404.9 32.0 3.5e-121 404.7 32.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH DUF262 PF03235.14 EMT51703.1 - 5.5e-35 121.5 5.4 5.5e-35 121.5 5.4 2.9 3 1 0 3 3 3 1 Protein of unknown function DUF262 DUF1524 PF07510.11 EMT51703.1 - 1.5e-25 89.7 3.8 1.5e-25 89.7 3.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1524) NUDIX PF00293.28 EMT51704.1 - 7e-20 71.4 0.3 7.6e-20 71.3 0.3 1.0 1 0 0 1 1 1 1 NUDIX domain TetR_N PF00440.23 EMT51705.1 - 3e-19 68.5 0.5 5.1e-19 67.8 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 EMT51705.1 - 7.8e-07 29.8 0.1 1.8e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_38 PF13936.6 EMT51705.1 - 0.0022 17.7 0.1 0.0056 16.4 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 EMT51705.1 - 0.0024 18.0 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 EMT51705.1 - 0.0064 16.3 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain LacI PF00356.21 EMT51705.1 - 0.12 12.1 0.0 0.73 9.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family CENP-B_N PF04218.13 EMT51705.1 - 0.14 11.8 0.1 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.15 EMT51705.1 - 0.15 12.1 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Lactamase_B PF00753.27 EMT51706.1 - 7.9e-27 94.6 0.2 9.1e-27 94.3 0.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMT51706.1 - 4.7e-07 29.5 0.0 1e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF3524 PF12038.8 EMT51706.1 - 0.21 11.4 0.0 8.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3524) DLH PF01738.18 EMT51707.1 - 5.2e-11 42.5 0.0 3.3e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 EMT51707.1 - 2.4e-10 39.6 0.0 3.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EMT51707.1 - 3.3e-05 23.5 0.1 5e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EMT51707.1 - 9.6e-05 22.1 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMT51707.1 - 0.00014 22.5 0.2 0.00021 22.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 EMT51707.1 - 0.0088 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 EMT51707.1 - 0.026 14.1 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) bPH_4 PF06713.11 EMT51708.1 - 1.5e-24 85.9 0.0 2e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial PH domain bPH_5 PF10882.8 EMT51708.1 - 0.00012 22.1 0.0 0.19 11.8 0.0 2.2 1 1 1 2 2 2 2 Bacterial PH domain bPH_2 PF03703.14 EMT51708.1 - 0.028 14.6 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain PALP PF00291.25 EMT51709.1 - 2.5e-54 184.7 0.0 3e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PFK PF00365.20 EMT51709.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase Acetyltransf_1 PF00583.25 EMT51710.1 - 1.4e-16 60.8 0.1 1.6e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT51710.1 - 2.4e-15 56.6 0.0 3e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT51710.1 - 4e-12 46.4 0.2 5.5e-12 45.9 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT51710.1 - 4.8e-09 36.4 0.0 7.3e-09 35.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT51710.1 - 1.5e-07 31.3 0.1 2.3e-07 30.7 0.1 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 EMT51710.1 - 3.4e-06 26.7 0.1 1.1e-05 25.0 0.1 1.8 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EMT51710.1 - 3.8e-05 23.7 0.0 6.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 EMT51710.1 - 0.0036 17.0 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_6 PF13480.7 EMT51710.1 - 0.017 15.3 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5535 PF17687.1 EMT51710.1 - 0.069 13.3 0.0 0.095 12.9 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5535) Acetyltransf_13 PF13880.6 EMT51710.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase CPBP PF02517.16 EMT51711.1 - 6.5e-16 58.5 6.8 9.9e-16 57.9 6.8 1.3 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease DUF2087 PF09860.9 EMT51712.1 - 1.3e-28 98.9 1.8 1.1e-27 96.0 1.3 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2087) GerE PF00196.19 EMT51712.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family TetR_C_10 PF16295.5 EMT51712.1 - 0.055 13.8 0.4 0.12 12.7 0.0 1.8 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LexA_DNA_bind PF01726.16 EMT51712.1 - 0.081 12.7 0.1 10 5.9 0.1 3.2 1 1 1 2 2 2 0 LexA DNA binding domain DUF2318 PF10080.9 EMT51712.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) HTH_23 PF13384.6 EMT51712.1 - 0.3 10.9 2.6 0.71 9.7 0.0 2.7 3 0 0 3 3 3 0 Homeodomain-like domain GIY-YIG PF01541.24 EMT51713.1 - 4.2e-06 26.9 2.4 6.9e-06 26.2 2.4 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain Cupin_2 PF07883.11 EMT51716.1 - 1.4e-09 37.5 0.0 2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 EMT51716.1 - 0.016 15.1 0.8 0.022 14.6 0.6 1.5 1 1 0 1 1 1 0 Mannose-6-phosphate isomerase Pectinesterase PF01095.19 EMT51716.1 - 0.13 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Pectinesterase GHL10 PF02638.15 EMT51717.1 - 2.7e-92 309.2 4.7 3.6e-92 308.8 4.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase-like 10 GHL6 PF14871.6 EMT51717.1 - 1.4e-05 25.3 0.3 0.00023 21.3 0.0 2.8 2 1 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 Melibiase PF02065.18 EMT51717.1 - 3.2e-05 23.1 0.0 6.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Melibiase Glyco_hydro_66 PF13199.6 EMT51717.1 - 0.0027 16.4 0.1 0.0042 15.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 Glyco_hydro_18 PF00704.28 EMT51717.1 - 0.0055 16.5 3.0 0.0094 15.7 2.1 1.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 DUF4434 PF14488.6 EMT51717.1 - 0.0057 16.7 0.0 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4434) EII-Sor PF03609.14 EMT51717.1 - 0.14 11.6 3.0 0.2 11.1 3.0 1.2 1 0 0 1 1 1 0 PTS system sorbose-specific iic component ALG3 PF05208.13 EMT51719.1 - 0.032 13.7 0.8 0.039 13.4 0.8 1.4 1 1 0 1 1 1 0 ALG3 protein TMEMspv1-c74-12 PF11044.8 EMT51719.1 - 0.041 13.9 0.9 0.053 13.5 0.0 1.6 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Acetyltransf_1 PF00583.25 EMT51720.1 - 6.8e-16 58.5 0.1 8.8e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT51720.1 - 2.2e-12 47.2 0.0 2.8e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT51720.1 - 1.7e-10 41.1 0.1 2.2e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT51720.1 - 2.9e-10 40.1 0.0 6.4e-10 39.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT51720.1 - 4.9e-06 26.4 0.0 1.1e-05 25.3 0.0 1.6 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_15 PF17013.5 EMT51720.1 - 0.00021 20.8 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_8 PF13523.6 EMT51720.1 - 0.0037 16.9 0.0 0.008 15.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMT51720.1 - 0.0063 17.2 0.0 0.0073 17.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EMT51720.1 - 0.023 14.8 0.5 0.061 13.5 0.2 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT51720.1 - 0.095 12.8 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NMT PF01233.19 EMT51720.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.4 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain AMP-binding PF00501.28 EMT51721.1 - 4.7e-98 328.5 0.0 5.5e-98 328.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMT51721.1 - 4.7e-16 59.5 0.7 9.3e-16 58.6 0.7 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 EMT51721.1 - 0.052 13.9 0.1 0.22 11.9 0.1 2.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Response_reg PF00072.24 EMT51722.1 - 3.1e-25 88.5 0.0 7.4e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EMT51722.1 - 4e-18 66.0 0.0 9.4e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 EMT51722.1 - 1.8e-15 57.1 0.5 9.9e-07 29.0 0.0 3.1 2 1 0 2 2 2 2 PAS domain HisKA PF00512.25 EMT51722.1 - 9.1e-13 48.0 0.0 2.6e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 EMT51722.1 - 1.7e-10 40.7 0.1 0.00091 19.2 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 EMT51722.1 - 1.9e-10 40.7 0.2 1.1e-05 25.4 0.0 3.0 2 1 0 2 2 2 2 PAS fold PAS_4 PF08448.10 EMT51722.1 - 3.1e-06 27.4 0.0 0.045 14.0 0.0 3.3 2 1 0 2 2 2 2 PAS fold PAS_3 PF08447.12 EMT51722.1 - 0.0019 18.4 0.1 1.5 9.1 0.0 3.0 3 0 0 3 3 3 2 PAS fold HPTransfase PF10090.9 EMT51722.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain DUF2521 PF10730.9 EMT51722.1 - 0.28 11.2 3.6 0.18 11.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2521) CheR PF01739.18 EMT51723.1 - 1.1e-39 135.9 0.0 1.7e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 EMT51723.1 - 2e-14 53.0 1.0 7.3e-14 51.2 0.3 2.1 2 0 0 2 2 2 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.12 EMT51723.1 - 0.0011 19.6 0.1 0.03 15.1 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT51723.1 - 0.0055 17.4 0.1 0.31 11.8 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT51723.1 - 0.0059 16.4 0.0 0.055 13.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT51723.1 - 0.18 12.5 0.1 0.71 10.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain HATPase_c PF02518.26 EMT51724.1 - 9.6e-31 106.6 0.1 2.4e-30 105.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMT51724.1 - 1.1e-27 96.4 1.4 4.8e-27 94.4 1.4 2.2 1 0 0 1 1 1 1 Response regulator receiver domain GAF_2 PF13185.6 EMT51724.1 - 4.9e-17 62.5 0.0 1e-16 61.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 EMT51724.1 - 3.5e-15 55.8 0.1 3.5e-15 55.8 0.1 3.9 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain 4HB_MCP_1 PF12729.7 EMT51724.1 - 6e-15 55.3 10.3 6e-15 55.3 10.3 3.2 3 1 1 4 4 4 1 Four helix bundle sensory module for signal transduction GAF PF01590.26 EMT51724.1 - 5.1e-09 36.9 0.0 1.1e-08 35.8 0.0 1.6 1 0 0 1 1 1 1 GAF domain HAMP PF00672.25 EMT51724.1 - 3.1e-08 33.8 0.1 2.1e-07 31.2 0.0 2.6 2 0 0 2 2 2 1 HAMP domain TarH PF02203.15 EMT51724.1 - 1.6e-06 28.2 4.7 1.6e-06 28.2 4.7 2.2 2 0 0 2 2 2 1 Tar ligand binding domain homologue OKR_DC_1_N PF03709.15 EMT51724.1 - 0.00048 20.4 0.7 0.004 17.4 0.0 2.7 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, N-terminal domain EcsC PF12787.7 EMT51724.1 - 0.00091 19.0 0.0 1.2 8.8 0.0 3.9 3 1 1 4 4 4 1 EcsC protein family AI-2E_transport PF01594.16 EMT51724.1 - 1.6 7.8 4.2 12 4.9 0.4 2.7 2 0 0 2 2 2 0 AI-2E family transporter DUF948 PF06103.11 EMT51724.1 - 2 8.7 17.0 1.5 9.2 0.5 4.8 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Hormone_1 PF00103.20 EMT51724.1 - 3.8 7.2 14.1 1.3 8.7 0.2 2.7 2 1 0 2 2 2 0 Somatotropin hormone family FRG PF08867.11 EMT51724.1 - 4 8.5 6.1 2 9.4 0.0 2.9 3 0 0 3 3 3 0 FRG domain UPF0242 PF06785.11 EMT51724.1 - 4.6 7.3 25.5 3.2 7.8 14.2 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Neur_chan_memb PF02932.16 EMT51724.1 - 6.3 6.8 5.6 24 4.9 4.4 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ABC_tran PF00005.27 EMT51726.1 - 7e-37 127.0 0.0 9.6e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT51726.1 - 1.5e-11 44.7 0.1 2.5e-07 30.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51726.1 - 5.5e-10 39.1 0.1 5.2e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMT51726.1 - 0.00016 21.4 0.1 0.00029 20.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT51726.1 - 0.00019 21.9 0.1 0.00035 21.0 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT51726.1 - 0.00022 21.5 0.1 0.0011 19.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT51726.1 - 0.00062 19.7 0.3 0.0011 18.8 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 EMT51726.1 - 0.0019 18.4 0.1 0.0028 17.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMT51726.1 - 0.0021 17.8 0.4 0.0048 16.6 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 EMT51726.1 - 0.0034 16.1 0.0 0.035 12.7 0.0 1.9 1 1 1 2 2 2 1 AAA domain ATPase_2 PF01637.18 EMT51726.1 - 0.0072 16.3 0.1 0.07 13.0 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EMT51726.1 - 0.0073 16.8 0.1 0.019 15.5 0.1 1.7 2 0 0 2 2 1 1 AAA domain ABC_ATPase PF09818.9 EMT51726.1 - 0.0087 14.9 0.8 3.5 6.3 0.1 2.9 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 EMT51726.1 - 0.0096 15.5 0.4 0.15 11.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain CobU PF02283.16 EMT51726.1 - 0.013 15.0 0.4 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ATP_bind_1 PF03029.17 EMT51726.1 - 0.014 15.2 0.4 0.042 13.6 0.1 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 EMT51726.1 - 0.02 13.9 0.2 0.041 12.9 0.2 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EMT51726.1 - 0.02 15.4 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EMT51726.1 - 0.022 14.8 0.3 0.053 13.6 0.1 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 EMT51726.1 - 0.026 14.2 0.1 2.7 7.6 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 EMT51726.1 - 0.026 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 EMT51726.1 - 0.033 13.8 0.4 0.062 12.9 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RecA PF00154.21 EMT51726.1 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein FtsK_SpoIIIE PF01580.18 EMT51726.1 - 0.043 13.2 0.1 0.1 12.0 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 EMT51726.1 - 0.059 13.1 0.1 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 EMT51726.1 - 0.062 13.7 0.5 0.45 10.9 0.2 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EMT51726.1 - 0.066 12.4 0.3 0.16 11.2 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 EMT51726.1 - 0.066 12.9 0.2 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EMT51726.1 - 0.076 12.7 0.1 0.17 11.6 0.1 1.7 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 EMT51726.1 - 0.097 13.0 0.5 0.17 12.2 0.4 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMT51726.1 - 0.11 12.7 0.1 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EMT51726.1 - 0.11 12.5 0.0 0.56 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EMT51726.1 - 0.12 12.6 0.1 1.2 9.4 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.15 EMT51726.1 - 0.12 11.1 0.3 0.21 10.4 0.0 1.4 2 0 0 2 2 1 0 Adenovirus IVa2 protein DUF87 PF01935.17 EMT51726.1 - 0.14 12.2 0.3 0.25 11.4 0.2 1.6 1 1 0 1 1 1 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 EMT51726.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain BPD_transp_1 PF00528.22 EMT51727.1 - 5.7e-22 78.3 13.2 5.7e-22 78.3 13.2 1.6 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Flu_M2 PF00599.17 EMT51727.1 - 0.14 12.3 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 Influenza Matrix protein (M2) DUF2567 PF10821.8 EMT51727.1 - 0.35 10.9 6.6 0.048 13.7 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) SBP_bac_3 PF00497.20 EMT51728.1 - 2.3e-69 233.3 3.7 2.6e-69 233.1 3.7 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EMT51728.1 - 4.2e-08 33.1 0.7 8.5e-08 32.1 0.7 1.4 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EMT51728.1 - 9.9e-05 22.4 0.4 0.00071 19.6 0.3 2.0 1 1 1 2 2 2 1 NMT1/THI5 like Lig_chan-Glu_bd PF10613.9 EMT51728.1 - 0.00018 21.7 0.0 0.0004 20.6 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site 120_Rick_ant PF12574.8 EMT51728.1 - 0.0078 15.4 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 120 KDa Rickettsia surface antigen Methyltransf_31 PF13847.6 EMT51728.1 - 0.058 13.2 0.1 0.27 11.0 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain DUF1421 PF07223.11 EMT51728.1 - 0.093 12.6 0.2 11 5.9 0.0 3.2 2 1 0 2 2 2 0 UBA-like domain (DUF1421) MFS_1 PF07690.16 EMT51729.1 - 0.001 18.1 4.9 0.0014 17.7 4.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Bac_rhodopsin PF01036.18 EMT51729.1 - 0.019 14.6 0.9 0.022 14.4 0.9 1.1 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein SBP_bac_5 PF00496.22 EMT51730.1 - 3.1e-38 131.7 0.0 4.9e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle CdiI_2 PF18593.1 EMT51730.1 - 0.053 14.2 1.4 0.16 12.7 0.1 2.4 3 0 0 3 3 3 0 CdiI immunity protein AdoMet_dc PF02675.15 EMT51731.1 - 1.4e-31 108.8 0.1 4.3e-31 107.3 0.1 1.8 1 1 0 1 1 1 1 S-adenosylmethionine decarboxylase FAM92 PF06730.11 EMT51731.1 - 0.024 14.1 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 FAM92 protein DUF2812 PF11193.8 EMT51732.1 - 3.6e-23 81.9 0.2 6.5e-23 81.0 0.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2812) TMEM43 PF07787.12 EMT51732.1 - 1.1 8.6 3.7 1.6 8.1 3.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 PadR PF03551.14 EMT51733.1 - 5.3e-14 51.9 1.4 9.9e-14 51.1 1.4 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 EMT51733.1 - 0.0005 20.2 0.4 0.0017 18.5 0.2 1.9 1 1 1 2 2 2 1 Winged helix DNA-binding domain HTH_27 PF13463.6 EMT51733.1 - 0.00094 19.6 0.3 0.0034 17.8 0.1 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_45 PF14947.6 EMT51733.1 - 0.027 14.5 0.2 0.057 13.4 0.1 1.6 1 1 0 1 1 1 0 Winged helix-turn-helix Response_reg PF00072.24 EMT51734.1 - 1.1e-25 89.9 0.1 1.6e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EMT51734.1 - 1e-17 63.4 0.0 1.6e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EMT51734.1 - 6.4e-06 25.7 0.0 1.6e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT51734.1 - 0.00047 19.6 0.0 0.00089 18.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 EMT51734.1 - 0.0021 18.0 0.0 0.0072 16.3 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 EMT51734.1 - 0.028 14.2 0.0 0.13 12.1 0.0 2.1 1 1 0 2 2 2 0 Homeodomain-like domain HTH_11 PF08279.12 EMT51734.1 - 0.032 14.2 0.1 0.091 12.7 0.1 1.8 1 0 0 1 1 1 0 HTH domain HTH_40 PF14493.6 EMT51734.1 - 0.064 13.7 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HisKA_3 PF07730.13 EMT51735.1 - 4.3e-21 75.2 2.7 8.7e-21 74.2 1.6 2.0 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 EMT51735.1 - 9.3e-07 29.3 0.3 6.6e-06 26.6 0.3 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT51735.1 - 0.0058 16.6 0.1 0.012 15.5 0.1 1.6 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain DUF883 PF05957.13 EMT51735.1 - 0.79 10.4 3.4 1.2 9.8 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) S_4TM PF18159.1 EMT51735.1 - 9.8 5.4 8.9 0.21 10.9 0.4 2.1 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain FA_desaturase PF00487.24 EMT51736.1 - 1.5e-38 133.1 11.6 1.5e-38 133.1 11.6 1.3 1 1 0 1 1 1 1 Fatty acid desaturase RELT PF12606.8 EMT51736.1 - 0.16 11.0 1.9 0.34 9.9 1.9 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 GPI2 PF06432.11 EMT51736.1 - 0.44 9.9 4.9 0.4 10.1 0.8 2.3 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase MFS_1 PF07690.16 EMT51736.1 - 8.5 5.2 17.3 0.21 10.5 3.7 2.4 1 1 0 2 2 2 0 Major Facilitator Superfamily HTH_42 PF06224.12 EMT51737.1 - 1.1e-75 255.2 1.3 1.3e-75 255.0 1.3 1.0 1 0 0 1 1 1 1 Winged helix DNA-binding domain UvrD_C PF13361.6 EMT51738.1 - 4e-26 92.2 1.2 2.9e-12 46.6 0.1 2.2 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain NERD PF08378.11 EMT51738.1 - 6.9e-14 52.2 0.0 2.4e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Nuclease-related domain AAA_19 PF13245.6 EMT51738.1 - 1.3e-11 45.0 0.0 2.6e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EMT51738.1 - 9.2e-10 38.5 0.0 0.00018 21.1 0.0 2.5 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 EMT51738.1 - 4.1e-08 32.9 0.0 8.9e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 EMT51738.1 - 5.6e-06 26.5 0.0 1.8e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMT51738.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EMT51738.1 - 3.2e-05 23.6 1.3 0.00025 20.7 1.3 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EMT51738.1 - 7e-05 22.7 0.0 0.17 11.6 0.0 2.8 2 1 1 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EMT51738.1 - 0.0012 19.1 0.0 0.009 16.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF2949 PF11165.8 EMT51738.1 - 0.0053 17.0 0.1 2.4 8.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2949) NACHT PF05729.12 EMT51738.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain FAA_hydrolase PF01557.18 EMT51739.1 - 9.1e-08 32.0 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Adeno_Penton_B PF01686.17 EMT51739.1 - 0.17 10.3 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein HMGL-like PF00682.19 EMT51740.1 - 8e-57 192.8 6.2 1.1e-56 192.4 6.2 1.1 1 0 0 1 1 1 1 HMGL-like DmpG_comm PF07836.11 EMT51740.1 - 1.8e-32 110.6 0.3 5.3e-32 109.1 0.3 1.9 1 0 0 1 1 1 1 DmpG-like communication domain Glyco_trans_4_5 PF16994.5 EMT51740.1 - 0.028 14.1 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 Glycosyl-transferase family 4 AcetDehyd-dimer PF09290.11 EMT51741.1 - 2.7e-64 215.5 0.3 4.8e-64 214.7 0.3 1.4 1 0 0 1 1 1 1 Prokaryotic acetaldehyde dehydrogenase, dimerisation Semialdhyde_dh PF01118.24 EMT51741.1 - 1.4e-13 51.3 0.0 3.7e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EMT51741.1 - 0.00017 21.7 0.0 0.00051 20.2 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 EMT51741.1 - 0.00026 21.8 0.0 0.00056 20.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 EMT51741.1 - 0.001 19.6 0.5 0.0022 18.5 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EMT51741.1 - 0.0047 17.0 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EMT51741.1 - 0.008 16.4 0.0 0.072 13.4 0.0 2.3 1 1 1 2 2 2 1 TrkA-N domain IlvN PF07991.12 EMT51741.1 - 0.039 13.5 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ldh_1_N PF00056.23 EMT51741.1 - 0.052 13.6 0.0 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 EMT51741.1 - 0.055 14.1 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.19 EMT51741.1 - 0.074 13.8 0.0 0.25 12.1 0.0 2.0 1 1 0 1 1 1 0 CoA binding domain FAA_hydrolase PF01557.18 EMT51742.1 - 3.4e-11 43.2 0.0 5.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Aldedh PF00171.22 EMT51743.1 - 1.7e-176 587.3 0.0 1.9e-176 587.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EMT51743.1 - 0.00024 20.6 0.0 0.72 9.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) PRANC PF09372.10 EMT51743.1 - 0.033 14.5 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 PRANC domain YjgF_endoribonc PF14588.6 EMT51744.1 - 2.9e-34 118.3 0.1 3.4e-34 118.1 0.1 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 EMT51744.1 - 5.2e-20 71.7 0.0 6.6e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Amidohydro_2 PF04909.14 EMT51745.1 - 1.3e-59 202.3 0.2 1.5e-59 202.2 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase Terminase_1 PF03354.15 EMT51745.1 - 0.17 10.4 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Phage Terminase 3-HAO PF06052.12 EMT51746.1 - 2.6e-51 173.2 0.3 3e-51 173.0 0.3 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase AraC_binding PF02311.19 EMT51746.1 - 2.6e-06 27.4 0.0 4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 EMT51746.1 - 2.9e-06 26.9 0.0 4.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EMT51746.1 - 0.00064 19.3 0.0 0.00097 18.8 0.0 1.2 1 0 0 1 1 1 1 Cupin OrfB_Zn_ribbon PF07282.11 EMT51746.1 - 0.002 18.0 1.8 1.9 8.5 0.4 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain ARD PF03079.14 EMT51746.1 - 0.0041 17.3 0.1 0.0072 16.5 0.1 1.3 1 0 0 1 1 1 1 ARD/ARD' family Cupin_8 PF13621.6 EMT51746.1 - 0.016 14.9 0.0 0.46 10.2 0.0 2.2 1 1 1 2 2 2 0 Cupin-like domain DZR PF12773.7 EMT51746.1 - 0.018 15.0 0.9 0.039 14.0 0.9 1.5 1 1 0 1 1 1 0 Double zinc ribbon CpXC PF14353.6 EMT51746.1 - 0.047 13.7 0.7 0.1 12.7 0.7 1.5 1 0 0 1 1 1 0 CpXC protein DUF35_N PF12172.8 EMT51746.1 - 0.14 12.1 0.6 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf_UBZ PF18439.1 EMT51746.1 - 0.16 11.6 4.4 5.9 6.6 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger A2L_zn_ribbon PF08792.10 EMT51746.1 - 0.43 10.4 3.7 5.2 6.9 0.1 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain PHD PF00628.29 EMT51746.1 - 1.2 9.0 6.1 7 6.6 6.1 2.2 1 1 0 1 1 1 0 PHD-finger FMN_red PF03358.15 EMT51747.1 - 5.2e-31 107.5 0.0 6.9e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EMT51747.1 - 2.2e-07 30.8 0.0 5.6e-07 29.5 0.0 1.7 1 1 0 2 2 2 1 Flavodoxin-like fold HpaB_N PF11794.8 EMT51748.1 - 6.5e-94 314.6 0.0 8.6e-94 314.2 0.0 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 EMT51748.1 - 1.9e-54 183.8 0.0 2.7e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal DctM PF06808.12 EMT51749.1 - 8.2e-118 393.8 53.6 9.9e-118 393.5 53.6 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component CitMHS PF03600.16 EMT51749.1 - 4.1 6.5 66.0 9.2 5.4 33.6 2.2 1 1 1 2 2 2 0 Citrate transporter DctQ PF04290.12 EMT51750.1 - 8.6e-27 93.6 12.0 1.2e-26 93.2 12.0 1.2 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component FixQ PF05545.11 EMT51750.1 - 7.4 6.6 9.3 1.3 9.0 0.8 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DctP PF03480.13 EMT51751.1 - 3.5e-67 226.7 0.0 4.3e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 MCPsignal PF00015.21 EMT51752.1 - 2.6e-24 85.9 5.7 2.6e-24 85.9 5.7 1.9 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc7 PF08317.11 EMT51752.1 - 0.25 10.2 6.0 1.3 7.8 0.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein T7SS_ESX_EspC PF10824.8 EMT51752.1 - 0.25 11.8 2.6 13 6.4 0.0 3.1 2 2 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm AIP3 PF03915.13 EMT51752.1 - 0.31 10.1 5.6 0.41 9.7 5.6 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Laminin_II PF06009.12 EMT51752.1 - 1.8 8.6 6.7 0.31 11.0 0.6 2.1 2 0 0 2 2 2 0 Laminin Domain II Sec34 PF04136.15 EMT51752.1 - 1.8 8.4 7.4 4.1 7.3 1.1 2.2 2 0 0 2 2 2 0 Sec34-like family WXG100 PF06013.12 EMT51752.1 - 2.6 8.4 6.9 3.8 7.8 0.1 3.3 3 1 0 3 3 3 0 Proteins of 100 residues with WXG LPP PF04728.13 EMT51752.1 - 4.1 7.9 5.8 3.2 8.2 1.2 2.8 3 1 0 3 3 3 0 Lipoprotein leucine-zipper COG2 PF06148.11 EMT51752.1 - 5.5 7.1 6.5 5.4 7.1 1.2 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HTH_Crp_2 PF13545.6 EMT51753.1 - 5.9e-16 58.2 0.0 1.2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 EMT51753.1 - 2.7e-15 56.2 0.0 6e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_23 PF13384.6 EMT51753.1 - 0.00048 19.9 0.1 0.0027 17.4 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain TrmB PF01978.19 EMT51753.1 - 0.00059 19.7 0.0 0.0014 18.5 0.0 1.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Crp PF00325.20 EMT51753.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family MarR_2 PF12802.7 EMT51753.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 MarR family RepL PF05732.11 EMT51753.1 - 0.034 13.6 0.1 0.097 12.1 0.0 1.7 2 1 0 2 2 2 0 Firmicute plasmid replication protein (RepL) HTH_28 PF13518.6 EMT51753.1 - 0.1 12.7 0.2 0.22 11.7 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 EMT51753.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding cNMP_binding PF00027.29 EMT51754.1 - 3.5e-15 55.8 0.0 5.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 EMT51754.1 - 1.6e-13 50.4 0.1 2.6e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 EMT51754.1 - 0.00016 21.8 0.0 0.00029 21.0 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Phage_rep_org_N PF09681.10 EMT51754.1 - 0.048 13.6 0.1 0.095 12.6 0.1 1.4 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) Rrf2 PF02082.20 EMT51754.1 - 0.061 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_28 PF13518.6 EMT51754.1 - 0.093 12.9 0.1 0.81 9.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain FtsX PF02687.21 EMT51755.1 - 6.4e-11 42.6 14.5 1.5e-10 41.4 5.1 6.0 6 0 0 6 6 6 3 FtsX-like permease family ABC_tran PF00005.27 EMT51756.1 - 7.6e-34 117.2 0.1 1.3e-33 116.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT51756.1 - 1.5e-07 31.6 0.2 0.012 15.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EMT51756.1 - 0.00037 20.3 0.0 0.00084 19.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT51756.1 - 0.00038 20.1 0.2 0.00071 19.3 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EMT51756.1 - 0.00052 19.5 0.7 0.003 17.0 0.7 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMT51756.1 - 0.0013 19.2 0.4 0.0039 17.6 0.4 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT51756.1 - 0.0021 18.4 0.1 0.21 11.9 0.0 2.6 2 1 1 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EMT51756.1 - 0.0035 17.3 0.1 0.0067 16.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 EMT51756.1 - 0.0047 16.7 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EMT51756.1 - 0.005 17.3 0.1 0.057 13.8 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EMT51756.1 - 0.0055 15.8 0.0 0.0093 15.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 EMT51756.1 - 0.0085 15.7 0.3 0.28 10.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 EMT51756.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 EMT51756.1 - 0.024 13.8 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 EMT51756.1 - 0.025 15.1 0.2 0.025 15.1 0.2 1.7 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 EMT51756.1 - 0.028 14.0 0.1 0.056 13.0 0.1 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EMT51756.1 - 0.038 13.9 0.0 0.06 13.3 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EMT51756.1 - 0.044 13.7 0.3 0.94 9.4 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.6 EMT51756.1 - 0.048 14.2 0.0 0.092 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMT51756.1 - 0.051 13.8 0.0 0.29 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EMT51756.1 - 0.067 13.3 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 EMT51756.1 - 0.089 12.8 0.1 0.2 11.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_13 PF13166.6 EMT51756.1 - 0.093 11.4 0.1 0.26 9.9 0.1 1.6 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 EMT51756.1 - 0.096 12.6 0.1 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain SRPRB PF09439.10 EMT51756.1 - 0.12 11.8 0.2 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EMT51756.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RrnaAD PF00398.20 EMT51757.1 - 4.3e-45 153.9 0.0 5.8e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EMT51757.1 - 6.1e-07 30.1 0.0 1.9e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 EMT51757.1 - 0.00017 21.4 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 EMT51757.1 - 0.0002 21.2 0.0 0.00023 21.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT51757.1 - 0.00057 20.5 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EMT51757.1 - 0.0053 16.7 0.0 0.0085 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EMT51757.1 - 0.0069 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EMT51757.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 EMT51757.1 - 0.045 12.8 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase FtsJ PF01728.19 EMT51757.1 - 0.058 13.5 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 EMT51757.1 - 0.074 13.8 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EMT51757.1 - 0.2 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FeS_assembly_P PF01883.19 EMT51758.1 - 7.2e-23 80.5 0.7 9.7e-23 80.1 0.7 1.2 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein ACR_tran PF00873.19 EMT51758.1 - 0.12 10.0 0.0 0.12 10.0 0.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Collagen_bind PF05737.12 EMT51759.1 - 9.4e-76 252.3 36.1 4.1e-23 82.0 1.7 6.0 5 1 0 5 5 5 5 Collagen binding domain SpaA PF17802.1 EMT51759.1 - 2.9e-52 174.9 32.2 5.8e-17 61.8 0.1 7.5 7 1 0 7 7 7 4 Prealbumin-like fold domain SdrD_B PF17210.3 EMT51759.1 - 4.4e-10 39.8 8.6 0.031 14.5 0.0 6.0 4 1 0 5 5 5 2 SdrD B-like domain Big_9 PF17963.1 EMT51759.1 - 3.7e-09 37.2 1.8 3.7e-09 37.2 1.8 4.9 5 0 0 5 5 5 1 Bacterial Ig domain Big_8 PF17961.1 EMT51759.1 - 1.1e-07 31.9 0.1 1.1e-07 31.9 0.1 5.4 6 0 0 6 6 6 1 Bacterial Ig domain CarboxypepD_reg PF13620.6 EMT51759.1 - 2.1e-06 27.9 2.1 0.57 10.5 0.0 5.6 6 1 0 6 6 4 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EMT51759.1 - 0.00042 20.3 0.8 4.7 7.3 0.0 5.3 5 0 0 5 5 5 1 CarboxypepD_reg-like domain Gram_pos_anchor PF00746.21 EMT51759.1 - 0.00053 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 LPXTG cell wall anchor motif Cadherin_4 PF17803.1 EMT51759.1 - 0.0015 19.1 1.0 1.8 9.2 0.0 5.1 4 0 0 4 4 4 1 Bacterial cadherin-like domain DUF11 PF01345.18 EMT51759.1 - 0.0028 17.9 0.1 0.063 13.6 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF11 Cupredoxin_1 PF13473.6 EMT51759.1 - 0.051 13.7 0.1 8.6 6.5 0.0 3.9 3 0 0 3 3 3 0 Cupredoxin-like domain Cadherin_5 PF17892.1 EMT51759.1 - 0.14 12.1 10.7 0.16 11.9 0.1 5.1 5 1 0 5 5 5 0 Cadherin-like domain Big_6 PF17936.1 EMT51759.1 - 2.3 8.5 6.3 3.5 8.0 0.0 4.4 5 0 0 5 5 5 0 Bacterial Ig domain Transglut_core PF01841.19 EMT51760.1 - 1.8e-26 92.8 0.1 2.9e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 EMT51760.1 - 5.6e-08 32.5 1.2 6.5e-07 29.0 1.0 2.3 1 1 0 1 1 1 1 Transglutaminase-like domain Transglut_core3 PF13471.6 EMT51760.1 - 2e-05 24.5 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 EMT51760.1 - 0.0043 16.7 0.5 0.0043 16.7 0.5 2.0 1 1 1 2 2 2 1 Rad4 transglutaminase-like domain EDR1 PF14381.6 EMT51760.1 - 0.08 12.7 0.0 0.48 10.1 0.0 2.1 1 1 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Phage_holin_7_1 PF16081.5 EMT51760.1 - 0.12 12.6 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Sortase PF04203.13 EMT51761.1 - 1.7e-28 98.9 0.0 2.4e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Sortase domain Response_reg PF00072.24 EMT51762.1 - 4.5e-22 78.3 0.4 9e-22 77.4 0.4 1.5 1 0 0 1 1 1 1 Response regulator receiver domain BTAD PF03704.17 EMT51762.1 - 1.6e-12 48.1 0.2 3e-12 47.2 0.2 1.4 1 0 0 1 1 1 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 EMT51762.1 - 1.4e-07 31.4 0.5 1e-06 28.7 0.1 2.5 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal Sigma70_r2 PF04542.14 EMT51764.1 - 4e-16 58.5 0.7 1.3e-15 56.9 0.5 1.9 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT51764.1 - 5.5e-14 51.6 0.0 9.9e-14 50.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT51764.1 - 4.1e-06 26.2 0.0 8.3e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT51764.1 - 0.00042 20.3 0.1 0.0018 18.2 0.1 1.8 1 1 0 1 1 1 1 ECF sigma factor GerE PF00196.19 EMT51764.1 - 0.026 14.1 0.3 0.076 12.6 0.2 1.8 1 1 1 2 2 2 0 Bacterial regulatory proteins, luxR family ACPS PF01648.20 EMT51765.1 - 2.5e-12 46.9 0.0 4.8e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PP-binding PF00550.25 EMT51766.1 - 1.4e-06 28.5 0.1 1.9e-06 28.1 0.1 1.3 1 1 0 1 1 1 1 Phosphopantetheine attachment site ImmE5 PF11480.8 EMT51766.1 - 0.1 13.1 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Colicin-E5 Imm protein ACP_syn_III_C PF08541.10 EMT51767.1 - 6.2e-32 109.6 0.2 1.1e-30 105.7 0.1 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EMT51767.1 - 1.2e-19 69.9 0.2 3e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EMT51767.1 - 3.3e-07 30.0 0.1 0.0001 21.8 0.0 2.1 2 0 0 2 2 2 2 Thiolase, N-terminal domain Chal_sti_synt_N PF00195.19 EMT51767.1 - 8.8e-07 28.6 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain SpoVAD PF07451.11 EMT51767.1 - 8.5e-06 24.7 0.1 0.0054 15.5 0.1 2.4 2 1 0 2 2 2 2 Stage V sporulation protein AD (SpoVAD) Thiolase_C PF02803.18 EMT51767.1 - 0.0015 18.1 0.1 0.052 13.2 0.0 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain FAE1_CUT1_RppA PF08392.12 EMT51767.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.15 EMT51767.1 - 0.094 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain TPP_enzyme_N PF02776.18 EMT51768.1 - 5.4e-44 149.8 0.0 8.4e-42 142.7 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMT51768.1 - 1.9e-26 92.4 0.0 5.4e-26 91.0 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EMT51768.1 - 4.5e-18 65.5 0.1 2.2e-16 60.0 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M_2 PF16582.5 EMT51768.1 - 0.00095 18.9 0.0 0.004 16.9 0.0 1.9 2 0 0 2 2 2 1 Middle domain of thiamine pyrophosphate DUF3088 PF11287.8 EMT51768.1 - 0.01 15.6 0.0 0.72 9.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3088) Aldedh PF00171.22 EMT51769.1 - 2.2e-27 95.7 0.0 4.5e-27 94.7 0.0 1.4 2 0 0 2 2 2 1 Aldehyde dehydrogenase family LuxC PF05893.14 EMT51769.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) AMP-binding PF00501.28 EMT51770.1 - 9.8e-69 232.0 0.0 1.3e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMT51770.1 - 5.5e-05 24.1 0.0 0.0003 21.7 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Acyl_transf_1 PF00698.21 EMT51771.1 - 0.11 12.0 0.1 0.31 10.5 0.1 1.8 1 1 0 1 1 1 0 Acyl transferase domain Acyl_transf_1 PF00698.21 EMT51772.1 - 0.0067 16.0 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 Acyl transferase domain adh_short_C2 PF13561.6 EMT51773.1 - 7.9e-68 228.5 3.1 9e-68 228.3 3.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT51773.1 - 2e-60 203.6 1.8 2.4e-60 203.4 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT51773.1 - 5.4e-15 55.8 0.6 7.2e-15 55.3 0.6 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMT51773.1 - 3.4e-07 30.0 0.5 1.6e-06 27.7 0.5 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMT51773.1 - 5.6e-07 29.3 0.6 2e-06 27.5 0.6 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMT51773.1 - 4.6e-05 22.7 0.5 8.3e-05 21.9 0.5 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1161 PF06649.12 EMT51773.1 - 0.031 14.5 1.4 0.084 13.1 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) NmrA PF05368.13 EMT51773.1 - 0.049 13.2 0.7 0.088 12.3 0.7 1.4 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 EMT51773.1 - 0.05 12.6 0.7 0.1 11.6 0.7 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ATP-synt_ab PF00006.25 EMT51773.1 - 0.053 13.2 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NAD_binding_10 PF13460.6 EMT51773.1 - 0.065 13.1 2.0 0.15 12.0 1.9 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Acetyltransf_3 PF13302.7 EMT51774.1 - 2.6e-06 28.2 0.2 5.3e-06 27.2 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT51774.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF2007 PF09413.10 EMT51774.1 - 0.16 12.1 0.1 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein GerE PF00196.19 EMT51775.1 - 2.4e-15 55.8 1.3 2.9e-15 55.6 0.4 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_24 PF13412.6 EMT51775.1 - 0.014 15.0 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 EMT51775.1 - 0.043 13.6 0.2 0.3 10.9 0.0 2.5 3 1 1 4 4 4 0 HTH DNA binding domain HTH_30 PF13556.6 EMT51775.1 - 0.048 13.5 0.2 0.12 12.2 0.1 1.7 1 1 1 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 EMT51775.1 - 0.07 13.2 0.1 3 8.0 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 EMT51776.1 - 4.2e-10 39.5 0.0 8.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix TPR_2 PF07719.17 EMT51776.1 - 7.4e-10 38.2 4.7 0.0012 18.8 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMT51776.1 - 3.3e-09 36.9 14.7 1.2e-06 28.7 4.2 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EMT51776.1 - 1.5e-08 34.2 7.4 0.00061 19.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMT51776.1 - 9.9e-08 31.6 5.5 0.00012 22.0 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat HTH_19 PF12844.7 EMT51776.1 - 1.2e-07 31.6 0.1 7.9e-07 29.0 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain TPR_MalT PF17874.1 EMT51776.1 - 1.8e-06 27.6 5.2 6.9e-06 25.7 1.4 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_4 PF07721.14 EMT51776.1 - 4e-05 23.9 0.4 10 7.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat HTH_31 PF13560.6 EMT51776.1 - 4.1e-05 23.8 0.0 9.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain TPR_1 PF00515.28 EMT51776.1 - 0.00019 21.1 5.3 0.15 12.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMT51776.1 - 0.0021 18.7 0.5 0.81 10.7 0.0 3.9 4 1 1 5 5 4 1 Tetratricopeptide repeat ComR_TPR PF18710.1 EMT51776.1 - 0.0024 17.5 0.7 0.0047 16.5 0.2 1.7 2 0 0 2 2 2 1 ComR tetratricopeptide TPR_6 PF13174.6 EMT51776.1 - 0.0026 18.3 1.9 14 6.6 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EMT51776.1 - 0.0052 17.3 3.5 1.5 9.4 0.1 3.5 2 2 2 4 4 4 1 Tetratricopeptide repeat HTH_26 PF13443.6 EMT51776.1 - 0.0055 17.1 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain TPR_7 PF13176.6 EMT51776.1 - 7 6.9 6.5 18 5.7 0.2 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Beta_elim_lyase PF01212.21 EMT51777.1 - 6.4e-93 311.2 0.3 7.8e-93 310.9 0.3 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EMT51777.1 - 9.6e-09 34.9 0.0 1.7e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMT51777.1 - 0.00065 19.1 0.3 0.59 9.4 0.0 2.6 3 0 0 3 3 3 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EMT51777.1 - 0.0027 16.3 0.5 0.11 11.0 0.1 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 EMT51777.1 - 0.012 14.3 0.4 0.34 9.5 0.0 2.7 3 0 0 3 3 3 0 Aminotransferase class-III ATP-grasp_4 PF13535.6 EMT51778.1 - 1.9e-23 82.8 0.0 3.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 EMT51778.1 - 3.8e-18 65.4 0.0 8.2e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_N PF18130.1 EMT51778.1 - 7.6e-08 32.8 0.0 1.3e-06 28.8 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp N-terminal domain ATP-grasp_3 PF02655.14 EMT51778.1 - 1.9e-07 31.3 0.0 3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EMT51778.1 - 0.00036 20.1 0.1 0.00063 19.3 0.1 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EMT51778.1 - 0.00048 19.9 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 EMT51778.1 - 0.00084 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 EMT51778.1 - 0.004 16.7 0.0 0.029 13.9 0.0 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_TupA PF14305.6 EMT51778.1 - 0.092 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 TupA-like ATPgrasp PALP PF00291.25 EMT51779.1 - 1.3e-48 165.9 0.0 1.5e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA_22 PF13401.6 EMT51779.1 - 0.02 15.2 0.1 0.11 12.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain PTS-HPr PF00381.19 EMT51779.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 PTS HPr component phosphorylation site GHMP_kinases_N PF00288.26 EMT51780.1 - 5.4e-05 23.4 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMT51780.1 - 0.079 13.3 0.0 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 GHMP kinases C terminal DUF2209 PF09974.9 EMT51780.1 - 0.1 12.9 0.2 0.22 11.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) Lyase_1 PF00206.20 EMT51781.1 - 7e-31 107.8 0.1 3.8e-30 105.4 0.0 1.9 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 EMT51781.1 - 6e-06 26.9 0.1 2.2e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal DUF3347 PF11827.8 EMT51781.1 - 0.48 10.6 3.1 0.24 11.6 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Condensation PF00668.20 EMT51782.1 - 3.8e-111 372.0 4.0 5.6e-111 371.4 4.0 1.2 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 EMT51782.1 - 7.7e-93 311.4 0.0 1.1e-92 310.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 EMT51782.1 - 1.4e-33 117.0 0.0 4.1e-33 115.4 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 EMT51782.1 - 4.6e-14 52.5 0.1 1.3e-13 51.1 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EMT51782.1 - 4.5e-09 37.2 1.1 2.6e-08 34.7 0.5 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.7 EMT51782.1 - 0.0078 16.8 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EMT51782.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMT51782.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.28 EMT51783.1 - 7.2e-288 953.9 0.0 3.9e-107 358.5 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EMT51783.1 - 6.9e-206 684.3 22.1 6.7e-104 348.1 7.3 2.6 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 EMT51783.1 - 3.8e-39 132.9 0.0 2.6e-14 53.3 0.0 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EMT51783.1 - 1.3e-27 96.6 0.1 9.1e-10 39.4 0.0 4.6 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain AATase PF07247.12 EMT51783.1 - 0.00077 18.1 2.6 0.0015 17.1 1.0 2.2 2 1 0 2 2 2 1 Alcohol acetyltransferase DUF3134 PF11332.8 EMT51783.1 - 0.14 12.5 0.1 0.64 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) DUF2935 PF11155.8 EMT51783.1 - 0.17 12.2 1.7 0.54 10.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) ketoacyl-synt PF00109.26 EMT51784.1 - 1.3e-51 175.7 1.4 1.6e-50 172.0 0.5 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMT51784.1 - 4.3e-39 133.2 1.9 1.1e-38 131.8 0.8 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EMT51784.1 - 0.0028 17.1 3.6 0.01 15.2 0.8 2.6 3 0 0 3 3 3 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EMT51784.1 - 0.045 14.2 0.1 0.14 12.6 0.1 1.8 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension 2TM PF13239.6 EMT51785.1 - 0.00026 21.2 0.8 0.00026 21.2 0.8 3.1 2 1 0 2 2 2 1 2TM domain FixP_N PF14715.6 EMT51785.1 - 1.3 8.8 0.1 1.3 8.8 0.1 3.9 5 0 0 5 5 5 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Beta-lactamase PF00144.24 EMT51786.1 - 1.1e-32 113.6 0.0 1.6e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Nop14 PF04147.12 EMT51786.1 - 5.8 5.0 12.6 8 4.5 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family Acetyltransf_10 PF13673.7 EMT51787.1 - 1.3e-05 25.2 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT51787.1 - 5.7e-05 23.5 0.0 0.00039 20.8 0.0 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT51787.1 - 0.0089 16.3 0.0 0.014 15.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EMT51788.1 - 4.4e-25 89.0 0.0 5.4e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT51788.1 - 2.4e-11 43.9 0.1 3.1e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EMT51788.1 - 8.7e-11 42.2 0.3 1.2e-10 41.8 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMT51788.1 - 1e-05 25.3 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT51789.1 - 8.6e-15 55.0 0.0 1.4e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT51789.1 - 7e-10 38.9 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT51789.1 - 6.6e-09 36.0 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT51789.1 - 1.2e-07 32.1 0.0 2.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EMT51789.1 - 9.7e-06 25.2 0.2 1.8e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 Putative acetyl-transferase FR47 PF08445.10 EMT51789.1 - 0.0046 16.9 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF5416 PF17437.2 EMT51789.1 - 0.015 15.1 0.3 0.025 14.4 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5416) Acetyltransf_CG PF14542.6 EMT51789.1 - 0.094 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TetR_N PF00440.23 EMT51791.1 - 3.2e-13 49.2 0.5 7.3e-13 48.1 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EMT51791.1 - 0.02 15.2 4.5 0.047 14.0 0.1 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CRF PF00473.17 EMT51791.1 - 0.44 10.7 2.0 6.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Corticotropin-releasing factor family Glyoxalase PF00903.25 EMT51794.1 - 4.3e-05 23.7 0.1 6.3e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EMT51794.1 - 0.00034 20.5 0.0 0.00053 19.9 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EMT51794.1 - 0.0037 18.0 0.0 0.0056 17.4 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain TPR_5 PF12688.7 EMT51795.1 - 1.3e-15 57.7 0.0 2.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Tetratrico peptide repeat TPR_16 PF13432.6 EMT51795.1 - 4.3e-13 49.7 1.2 1.7e-06 28.5 0.0 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMT51795.1 - 1.5e-09 37.8 5.2 4.4e-05 24.0 0.0 4.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMT51795.1 - 1.9e-09 37.9 2.6 2.1e-07 31.3 0.0 2.8 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMT51795.1 - 1.3e-08 35.0 4.7 4.2e-07 30.2 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMT51795.1 - 1.3e-08 34.3 10.6 0.00043 20.2 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMT51795.1 - 1.8e-08 33.8 2.3 0.002 17.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMT51795.1 - 7e-08 32.1 1.0 0.0065 16.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMT51795.1 - 1.1e-07 31.4 5.0 0.00033 20.5 0.3 4.0 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EMT51795.1 - 1.1e-05 25.8 1.7 0.35 11.6 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMT51795.1 - 1.2e-05 25.4 0.8 0.06 13.6 0.1 2.5 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EMT51795.1 - 6.9e-05 22.6 5.9 1.2 9.1 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 EMT51795.1 - 0.0048 16.9 0.5 2.3 8.3 0.0 3.3 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 EMT51795.1 - 0.0075 16.6 0.3 0.12 12.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 EMT51795.1 - 0.016 15.2 2.9 0.59 10.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SIX1_SD PF16878.5 EMT51795.1 - 0.049 14.2 0.1 0.086 13.4 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain SRP_TPR_like PF17004.5 EMT51795.1 - 0.059 13.4 0.7 0.12 12.3 0.3 1.7 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_11 PF13414.6 EMT51795.1 - 0.35 10.6 8.5 19 5.1 0.0 4.5 4 1 0 4 4 4 0 TPR repeat TPR_17 PF13431.6 EMT51795.1 - 0.58 10.7 5.2 4.2 8.0 0.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMT51795.1 - 1.1 10.1 0.1 1.1 10.1 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat tRNA_U5-meth_tr PF05958.11 EMT51796.1 - 1.1e-24 87.1 0.0 5.1e-24 84.9 0.0 1.9 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 EMT51796.1 - 7.9e-14 51.4 0.3 7.9e-14 51.4 0.3 1.8 2 0 0 2 2 2 1 TRAM domain Methyltransf_31 PF13847.6 EMT51796.1 - 1.1e-11 44.7 0.0 2.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT51796.1 - 3.8e-07 30.7 0.0 1.2e-06 29.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EMT51796.1 - 1.9e-06 27.5 0.0 3.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EMT51796.1 - 3.5e-06 26.9 0.5 1.1e-05 25.3 0.5 1.8 1 1 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EMT51796.1 - 1.1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EMT51796.1 - 0.0011 19.6 0.0 0.0034 18.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMT51796.1 - 0.0016 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EMT51796.1 - 0.012 15.6 3.5 0.051 13.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain TPMT PF05724.11 EMT51796.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) N6_N4_Mtase PF01555.18 EMT51796.1 - 0.055 13.2 0.0 0.055 13.2 0.0 2.2 3 0 0 3 3 2 0 DNA methylase UPF0020 PF01170.18 EMT51796.1 - 0.081 12.6 0.2 1.6 8.4 0.2 2.4 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 EMT51796.1 - 0.11 13.3 1.1 0.74 10.6 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain DAGK_cat PF00781.24 EMT51797.1 - 1.6e-37 127.9 0.0 3e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EMT51797.1 - 1.4e-05 24.5 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase TP_methylase PF00590.20 EMT51797.1 - 0.042 13.8 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Chaperone_III PF07824.12 EMT51797.1 - 0.17 12.1 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Type III secretion chaperone domain ROK PF00480.20 EMT51798.1 - 1e-70 238.5 3.6 1.2e-70 238.3 3.6 1.0 1 0 0 1 1 1 1 ROK family FGGY_N PF00370.21 EMT51798.1 - 0.00075 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EMT51798.1 - 0.0012 18.4 2.4 0.0022 17.5 0.5 2.2 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Cdd1 PF11731.8 EMT51799.1 - 2.2e-29 101.5 0.0 6.8e-29 99.9 0.0 1.7 1 1 1 2 2 2 1 Pathogenicity locus DUF4332 PF14229.6 EMT51799.1 - 0.011 16.0 0.1 0.015 15.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) DNA_pol_lambd_f PF10391.9 EMT51799.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 EMT51799.1 - 0.12 13.0 0.1 0.19 12.3 0.1 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain EamA PF00892.20 EMT51800.1 - 4.8e-42 143.4 40.7 6.5e-26 91.1 14.6 2.0 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EMT51800.1 - 0.0052 16.0 0.5 0.0052 16.0 0.5 2.4 2 1 0 2 2 2 1 UAA transporter family TPT PF03151.16 EMT51800.1 - 0.042 13.2 12.9 0.17 11.2 0.4 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family Neurensin PF14927.6 EMT51800.1 - 0.089 12.5 8.4 2.2 8.0 0.0 3.9 3 1 1 4 4 4 0 Neurensin AWPM-19 PF05512.11 EMT51800.1 - 0.091 12.9 10.1 0.23 11.7 0.9 3.4 2 1 1 3 3 3 0 AWPM-19-like family TssN PF17555.2 EMT51800.1 - 2.2 7.6 8.1 4.7 6.5 8.1 1.6 1 0 0 1 1 1 0 Type VI secretion system, TssN ABC2_membrane_3 PF12698.7 EMT51801.1 - 1.1e-30 107.0 4.9 1.2e-30 106.8 4.9 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EMT51801.1 - 8e-29 100.8 4.5 1.4e-28 100.0 4.5 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 EMT51801.1 - 1.8e-10 40.6 12.2 1.2e-09 37.9 8.1 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_4 PF12730.7 EMT51801.1 - 1.8e-05 24.7 6.3 1.8e-05 24.7 6.3 3.1 2 1 2 4 4 4 1 ABC-2 family transporter protein ABC_tran PF00005.27 EMT51802.1 - 2.2e-30 106.0 0.0 4.2e-30 105.0 0.0 1.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EMT51802.1 - 3.6e-08 33.6 0.0 6.5e-05 22.9 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MukB PF04310.12 EMT51802.1 - 0.0095 15.8 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 MukB N-terminal AAA PF00004.29 EMT51802.1 - 0.012 16.1 0.0 0.13 12.6 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EMT51802.1 - 0.013 15.3 0.9 0.98 9.1 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EMT51802.1 - 0.017 15.6 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMT51802.1 - 0.021 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT51802.1 - 0.026 14.8 0.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMT51802.1 - 0.032 13.9 0.5 0.062 13.0 0.5 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EMT51802.1 - 0.059 13.0 0.1 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_27 PF13514.6 EMT51802.1 - 0.064 12.8 0.2 0.36 10.4 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EMT51802.1 - 0.26 11.0 0.0 3.9 7.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MOSC PF03473.17 EMT51804.1 - 1.2e-25 90.0 0.0 1.8e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 MOSC domain 3-alpha PF03475.14 EMT51804.1 - 5.8e-18 64.5 0.1 1.3e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 3-alpha domain Sigma70_r2 PF04542.14 EMT51805.1 - 3.9e-14 52.2 0.7 1.1e-13 50.7 0.7 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT51805.1 - 9.9e-13 47.6 0.0 2.4e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT51805.1 - 1.3e-08 34.3 0.1 4.1e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT51805.1 - 8.1e-05 22.6 0.2 0.00066 19.6 0.1 2.3 2 0 0 2 2 2 1 ECF sigma factor UPF0122 PF04297.14 EMT51805.1 - 0.0002 21.6 0.8 0.00047 20.3 0.1 2.0 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like FliT PF05400.13 EMT51805.1 - 0.0036 18.1 4.6 11 6.9 0.0 4.4 4 0 0 4 4 4 2 Flagellar protein FliT DUF4872 PF16169.5 EMT51805.1 - 0.057 13.2 0.0 0.21 11.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4872) HTH_16 PF12645.7 EMT51805.1 - 0.079 13.0 0.6 1 9.5 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 EMT51805.1 - 0.095 12.5 0.0 3.8 7.4 0.0 3.3 3 0 0 3 3 3 0 Homeodomain-like domain GatB_N PF02934.15 EMT51806.1 - 1.2e-118 395.4 0.0 1.6e-118 395.0 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EMT51806.1 - 1.7e-59 200.0 0.9 2.9e-59 199.2 0.9 1.4 1 0 0 1 1 1 1 GatB domain ApbA_C PF08546.11 EMT51806.1 - 0.074 13.3 0.2 0.14 12.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Amidase PF01425.21 EMT51807.1 - 5.3e-162 539.9 0.0 6e-162 539.7 0.0 1.0 1 0 0 1 1 1 1 Amidase Glu-tRNAGln PF02686.15 EMT51808.1 - 1.9e-23 82.5 0.7 2.7e-23 82.0 0.7 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit YflT PF11181.8 EMT51808.1 - 0.021 15.3 0.7 0.071 13.6 0.2 1.9 1 1 1 2 2 2 0 Heat induced stress protein YflT CHZ PF09649.10 EMT51808.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Histone chaperone domain CHZ AHSA1 PF08327.11 EMT51810.1 - 4.6e-22 78.6 0.2 5.4e-22 78.3 0.2 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EMT51810.1 - 0.00033 21.0 0.9 0.00049 20.4 0.9 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF3450 PF11932.8 EMT51810.1 - 0.018 14.3 0.0 0.018 14.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DsbC_N PF10411.9 EMT51810.1 - 0.11 12.0 0.1 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Disulfide bond isomerase protein N-terminus PS_Dcarbxylase PF02666.15 EMT51811.1 - 5.2e-63 212.2 0.0 6.2e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF3422 PF11902.8 EMT51811.1 - 0.0047 16.1 0.0 0.0069 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3422) GGDEF PF00990.21 EMT51812.1 - 4e-58 195.7 0.1 9.5e-58 194.5 0.1 1.6 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 EMT51812.1 - 4.2e-10 39.9 0.0 1.1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold GGDEF_2 PF17853.1 EMT51812.1 - 0.059 13.6 0.1 0.17 12.2 0.1 2.0 1 1 0 1 1 1 0 GGDEF-like domain PAS_9 PF13426.7 EMT51812.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 PAS domain Glycos_transf_4 PF00953.21 EMT51813.1 - 8.9e-36 123.3 15.0 8.9e-36 123.3 15.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 4 Aldedh PF00171.22 EMT51814.1 - 7.9e-158 525.8 0.1 1e-157 525.4 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4126 PF13548.6 EMT51814.1 - 0.21 11.3 2.3 0.21 11.3 1.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) CamS PF07537.11 EMT51815.1 - 8.5e-68 228.8 0.4 3.6e-67 226.8 0.4 1.7 1 1 0 1 1 1 1 CamS sex pheromone cAM373 precursor Sortilin-Vps10 PF15902.5 EMT51816.1 - 0.065 12.0 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, BNR PF02012.20 EMT51816.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.4 5 0 0 5 5 5 0 BNR/Asp-box repeat DNA_ligase_aden PF01653.18 EMT51817.1 - 3.2e-131 437.1 0.0 4.4e-131 436.7 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 EMT51817.1 - 6.3e-33 112.5 1.3 1.5e-32 111.3 1.3 1.7 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 EMT51817.1 - 9.3e-23 80.1 0.1 2.7e-22 78.6 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif BRCT PF00533.26 EMT51817.1 - 3.4e-14 53.0 0.0 1.3e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_ZBD PF03119.16 EMT51817.1 - 1.2e-11 44.4 3.9 1.2e-11 44.4 3.9 2.1 2 0 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain HHH_5 PF14520.6 EMT51817.1 - 3.8e-11 43.4 0.3 0.00036 21.1 0.1 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix domain PTCB-BRCT PF12738.7 EMT51817.1 - 1.5e-05 24.9 0.2 3.3e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 twin BRCT domain HHH PF00633.23 EMT51817.1 - 0.00047 19.9 0.0 0.0035 17.1 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif zf-IS66 PF13005.7 EMT51817.1 - 0.052 14.0 0.9 0.13 12.7 0.9 1.7 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 zf-NADH-PPase PF09297.11 EMT51817.1 - 0.14 11.8 0.6 0.28 10.9 0.6 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.10 EMT51817.1 - 0.16 12.1 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain UvrD-helicase PF00580.21 EMT51818.1 - 5.2e-83 279.2 0.8 1.5e-82 277.6 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EMT51818.1 - 6.7e-74 249.3 6.8 4e-73 246.8 6.8 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EMT51818.1 - 3.2e-34 118.4 0.1 2.6e-33 115.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EMT51818.1 - 4.6e-12 45.6 0.0 1.5e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EMT51818.1 - 7e-08 32.5 0.1 0.016 14.9 0.1 3.5 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EMT51818.1 - 3.1e-07 30.3 0.0 5.3e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Exonuc_V_gamma PF04257.14 EMT51818.1 - 0.00044 18.6 0.3 0.0011 17.3 0.0 1.7 2 0 0 2 2 2 1 Exodeoxyribonuclease V, gamma subunit AAA_11 PF13086.6 EMT51818.1 - 0.0096 15.7 1.8 0.048 13.4 0.0 2.7 3 1 0 3 3 3 1 AAA domain DUF2067 PF09840.9 EMT51818.1 - 0.077 12.6 2.2 0.1 12.2 0.5 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) DEAD PF00270.29 EMT51818.1 - 0.12 12.2 0.3 0.46 10.2 0.3 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase VanW PF04294.13 EMT51819.1 - 9.3e-38 128.8 0.0 1.2e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 VanW like protein GDPD PF03009.17 EMT51820.1 - 5.3e-57 193.5 0.0 6.6e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EMT51820.1 - 1.6e-06 28.3 0.0 0.00093 19.6 0.0 2.6 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 EMT51820.1 - 0.087 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain PcrB PF01884.17 EMT51821.1 - 1.7e-71 240.3 0.0 1.9e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 PcrB family Trp_syntA PF00290.20 EMT51821.1 - 0.00081 18.3 0.3 0.0053 15.6 0.1 2.1 2 1 0 2 2 2 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 EMT51821.1 - 0.036 13.5 0.0 0.082 12.3 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein Trp_repressor PF01371.19 EMT51822.1 - 4.5e-34 116.4 0.1 5.5e-34 116.2 0.1 1.0 1 0 0 1 1 1 1 Trp repressor protein HTH_23 PF13384.6 EMT51822.1 - 7e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 EMT51822.1 - 0.00025 20.8 0.5 0.00049 19.8 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EMT51822.1 - 0.0026 17.9 0.1 0.0036 17.4 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Arabinose_Isome PF02610.15 EMT51822.1 - 0.016 14.5 0.1 0.018 14.3 0.1 1.0 1 0 0 1 1 1 0 L-arabinose isomerase HTH_7 PF02796.15 EMT51822.1 - 0.02 15.0 0.2 0.041 14.0 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF5338 PF17273.2 EMT51822.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5338) HTH_49 PF18010.1 EMT51822.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain DUF3048 PF11258.8 EMT51823.1 - 9.6e-50 168.5 0.0 1.7e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3048) N-terminal domain DUF3048_C PF17479.2 EMT51823.1 - 2.6e-24 85.8 0.0 3.8e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3048) C-terminal domain Response_reg PF00072.24 EMT51824.1 - 4.9e-25 87.9 0.0 8.2e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT51824.1 - 9.5e-20 70.5 0.2 2.4e-19 69.2 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 EMT51825.1 - 1.5e-13 51.3 0.0 2.5e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT51825.1 - 2.3e-13 50.0 0.0 5.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EMT51825.1 - 2.7e-13 50.1 0.0 6.1e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 HAMP domain HATPase_c_5 PF14501.6 EMT51825.1 - 0.00029 20.7 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 EMT51825.1 - 0.014 15.3 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain FtsX PF02687.21 EMT51825.1 - 0.045 14.2 0.3 3.9 8.0 0.0 2.3 2 0 0 2 2 2 0 FtsX-like permease family BNIP3 PF06553.12 EMT51825.1 - 2.1 8.0 5.6 0.29 10.8 0.3 1.9 2 0 0 2 2 2 0 BNIP3 Peripla_BP_6 PF13458.6 EMT51826.1 - 1.6e-51 176.0 9.3 1.9e-51 175.8 9.3 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 EMT51826.1 - 1.9e-18 66.7 0.0 2.2e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 EMT51826.1 - 2.2e-10 40.1 1.4 4.1e-10 39.2 1.4 1.4 1 1 0 1 1 1 1 Periplasmic binding protein domain O-FucT PF10250.9 EMT51826.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase RTP PF02334.16 EMT51826.1 - 0.21 12.2 0.8 18 6.0 0.0 3.0 3 1 1 4 4 4 0 Replication terminator protein Peptidase_M20 PF01546.28 EMT51827.1 - 6.3e-30 104.4 0.2 8.5e-30 104.0 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT51827.1 - 3.6e-18 65.5 0.0 8.1e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT51827.1 - 1.1e-05 25.2 0.0 0.00018 21.3 0.0 2.3 2 1 0 2 2 2 1 Peptidase family M28 BPD_transp_1 PF00528.22 EMT51828.1 - 1.9e-18 66.9 19.9 1.9e-18 66.9 19.9 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EMT51829.1 - 7.2e-12 45.4 34.3 2.9e-10 40.2 34.3 2.2 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EMT51830.1 - 6.4e-35 120.6 0.0 1.3e-34 119.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 EMT51830.1 - 2.6e-11 43.5 0.0 5.7e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 EMT51830.1 - 5.3e-09 36.3 0.5 2.8e-06 27.4 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51830.1 - 0.00019 20.9 0.2 0.0015 18.0 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMT51830.1 - 0.0039 17.6 0.0 0.0081 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMT51830.1 - 0.0049 16.8 0.1 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 EMT51830.1 - 0.007 16.8 0.1 0.049 14.1 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMT51830.1 - 0.0084 16.4 0.7 0.065 13.5 0.7 2.1 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EMT51830.1 - 0.039 13.9 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_ATPase PF09818.9 EMT51830.1 - 0.043 12.6 0.0 0.26 10.0 0.0 2.0 1 1 0 1 1 1 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 EMT51830.1 - 0.052 13.3 0.1 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain MIT_C PF16565.5 EMT51830.1 - 0.062 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT AAA_23 PF13476.6 EMT51830.1 - 0.09 13.3 0.3 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EMT51830.1 - 0.13 12.0 0.1 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain TOBE PF03459.17 EMT51830.1 - 0.13 12.6 0.0 7 7.0 0.0 2.6 2 1 0 2 2 2 0 TOBE domain CysA_C_terminal PF17850.1 EMT51830.1 - 0.15 12.6 0.0 0.38 11.4 0.0 1.8 1 0 0 1 1 1 0 CysA C-terminal regulatory domain SBP_bac_6 PF13343.6 EMT51831.1 - 1.8e-31 109.5 1.9 3e-31 108.7 1.9 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EMT51831.1 - 7.2e-31 108.0 8.5 1.1e-30 107.5 8.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EMT51831.1 - 2e-21 76.8 0.2 3e-21 76.2 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT51831.1 - 2.3e-15 57.4 7.5 3.7e-15 56.7 7.5 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like_2 PF12849.7 EMT51831.1 - 0.0021 17.8 1.4 0.29 10.8 0.0 2.6 1 1 0 2 2 2 2 PBP superfamily domain IclR PF01614.18 EMT51832.1 - 1.1e-24 86.7 0.0 1.9e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EMT51832.1 - 2.7e-12 46.3 0.0 5.7e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EMT51832.1 - 3.2e-06 26.9 0.0 2.8e-05 23.9 0.0 2.4 3 0 0 3 3 3 1 MarR family MarR PF01047.22 EMT51832.1 - 3.6e-06 26.8 0.0 7.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EMT51832.1 - 0.00022 20.7 0.0 0.00045 19.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF4423 PF14394.6 EMT51832.1 - 0.00088 19.0 0.0 0.0079 15.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) HTH_Mga PF08280.11 EMT51832.1 - 0.0011 18.9 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_5 PF01022.20 EMT51832.1 - 0.0013 18.6 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 EMT51832.1 - 0.0025 17.7 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 HTH domain TrmB PF01978.19 EMT51832.1 - 0.0032 17.3 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_54 PF18607.1 EMT51832.1 - 0.014 15.4 0.1 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 ParA helix turn helix domain HTH_27 PF13463.6 EMT51832.1 - 0.017 15.6 0.0 0.045 14.2 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain PadR PF03551.14 EMT51832.1 - 0.017 15.1 0.3 0.035 14.1 0.3 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_41 PF14502.6 EMT51832.1 - 0.022 14.5 0.1 0.096 12.4 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain FeoC PF09012.10 EMT51832.1 - 0.041 14.0 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator Fe_dep_repress PF01325.19 EMT51832.1 - 0.055 13.7 0.0 0.55 10.5 0.1 2.3 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_34 PF13601.6 EMT51832.1 - 0.077 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_45 PF14947.6 EMT51832.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_20 PF12840.7 EMT51832.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 EMT51832.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Rio2_N PF09202.11 EMT51832.1 - 0.14 12.4 0.2 0.45 10.8 0.2 1.9 1 1 0 1 1 1 0 Rio2, N-terminal MerR_1 PF13411.6 EMT51833.1 - 4e-19 68.5 1.0 9.9e-19 67.2 0.4 1.9 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 EMT51833.1 - 2.4e-15 56.0 0.6 4.4e-15 55.2 0.6 1.5 1 0 0 1 1 1 1 MerR family regulatory protein CREPT PF16566.5 EMT51833.1 - 0.031 14.4 4.3 0.056 13.6 4.2 1.6 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour MukF_M PF17192.4 EMT51833.1 - 0.047 13.4 1.1 0.075 12.8 1.1 1.4 1 0 0 1 1 1 0 MukF middle domain FAM76 PF16046.5 EMT51833.1 - 0.053 12.9 2.3 0.046 13.1 2.3 1.1 1 0 0 1 1 1 0 FAM76 protein DegS PF05384.11 EMT51833.1 - 0.054 13.0 6.5 0.12 11.8 6.5 1.7 1 1 0 1 1 1 0 Sensor protein DegS Spc7 PF08317.11 EMT51833.1 - 0.062 12.2 8.0 0.075 11.9 8.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HTH_3 PF01381.22 EMT51833.1 - 0.15 12.2 2.3 0.22 11.6 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix CC2-LZ PF16516.5 EMT51833.1 - 0.3 11.5 6.5 1.6 9.1 0.4 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator MerR-DNA-bind PF09278.11 EMT51833.1 - 0.65 10.6 6.9 1.2 9.7 3.5 2.8 1 1 1 2 2 2 0 MerR, DNA binding Sigma70_r3 PF04539.16 EMT51833.1 - 0.92 9.6 0.0 0.92 9.6 0.0 3.4 4 0 0 4 4 4 0 Sigma-70 region 3 MFS_1 PF07690.16 EMT51834.1 - 1.2e-42 146.1 64.6 1.3e-30 106.5 32.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMT51834.1 - 0.18 10.3 37.5 0.093 11.3 18.5 2.9 1 1 2 3 3 3 0 MFS/sugar transport protein Peptidase_M29 PF02073.15 EMT51836.1 - 1.4e-06 27.3 0.2 0.00028 19.8 0.0 2.1 2 0 0 2 2 2 2 Thermophilic metalloprotease (M29) NMO PF03060.15 EMT51836.1 - 0.011 15.2 0.4 0.031 13.7 0.2 1.6 1 1 1 2 2 2 0 Nitronate monooxygenase PTS-HPr PF00381.19 EMT51836.1 - 0.024 14.9 0.0 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 PTS HPr component phosphorylation site Aminotran_5 PF00266.19 EMT51837.1 - 3.7e-91 305.8 0.0 4.3e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMT51837.1 - 2.6e-11 43.5 0.0 6.2e-11 42.2 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EMT51837.1 - 1.6e-07 30.9 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EMT51837.1 - 1.7e-05 24.1 0.0 2.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMT51837.1 - 0.00032 19.4 0.0 0.00055 18.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme LPAM_2 PF13627.6 EMT51837.1 - 0.22 11.4 0.4 0.5 10.3 0.4 1.6 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Peptidase_M24 PF00557.24 EMT51838.1 - 7e-65 218.6 0.4 9.7e-65 218.2 0.4 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EMT51838.1 - 4.4e-19 69.4 0.0 7.1e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain OPT PF03169.15 EMT51839.1 - 1.7e-36 126.1 41.3 3.2e-24 85.5 29.0 2.1 1 1 1 2 2 2 2 OPT oligopeptide transporter protein IclR PF01614.18 EMT51840.1 - 5.8e-31 107.0 0.0 8.6e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EMT51840.1 - 1.6e-13 50.2 0.0 7.3e-13 48.1 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain Rrf2 PF02082.20 EMT51840.1 - 0.00021 21.6 0.0 0.64 10.4 0.0 2.4 2 0 0 2 2 2 2 Transcriptional regulator HTH_23 PF13384.6 EMT51840.1 - 0.0014 18.3 0.0 0.0065 16.2 0.0 2.1 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 EMT51840.1 - 0.0033 17.3 0.0 0.0096 15.8 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 EMT51840.1 - 0.014 15.3 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_32 PF13565.6 EMT51840.1 - 0.025 15.2 0.0 0.16 12.6 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain MarR PF01047.22 EMT51840.1 - 0.03 14.2 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 MarR family FeoC PF09012.10 EMT51840.1 - 0.046 13.8 0.0 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_38 PF13936.6 EMT51840.1 - 0.074 12.8 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2100 PF09873.9 EMT51840.1 - 0.082 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) UPF0240 PF06784.11 EMT51840.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) AzlD PF05437.12 EMT51841.1 - 9.5e-20 70.6 9.3 1.1e-19 70.5 9.3 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein (AzlD) TraL PF07178.11 EMT51841.1 - 0.14 12.7 0.6 0.14 12.7 0.6 2.1 2 1 0 2 2 2 0 TraL protein PhoR PF11808.8 EMT51841.1 - 9.9 6.7 13.9 0.16 12.4 5.3 2.1 2 1 0 2 2 2 0 Phosphate regulon sensor protein PhoR AzlC PF03591.14 EMT51842.1 - 1.3e-35 122.7 5.8 1.3e-35 122.7 5.8 2.2 2 1 0 2 2 2 1 AzlC protein PT-VENN PF04829.13 EMT51842.1 - 0.078 13.1 6.0 2.1 8.5 4.1 2.7 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif ATP-synt_J PF04911.12 EMT51842.1 - 0.086 12.4 0.1 0.28 10.8 0.1 1.9 1 0 0 1 1 1 0 ATP synthase j chain Aminotran_1_2 PF00155.21 EMT51843.1 - 9.2e-22 77.7 0.0 1.4e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EMT51843.1 - 1.1e-13 50.7 1.2 3.3e-13 49.1 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 EMT51843.1 - 0.00047 19.1 0.0 0.00071 18.5 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase MarR_2 PF12802.7 EMT51843.1 - 0.058 13.3 0.7 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 MarR family HTH_41 PF14502.6 EMT51843.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain ABC_tran PF00005.27 EMT51844.1 - 4.6e-34 117.9 0.1 7.5e-34 117.2 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT51844.1 - 1.3e-07 31.7 0.1 0.013 15.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMT51844.1 - 0.0016 18.9 0.0 0.002 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMT51844.1 - 0.0019 18.0 0.1 0.0086 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EMT51844.1 - 0.002 17.8 0.1 0.0053 16.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EMT51844.1 - 0.0027 17.2 0.6 0.12 11.8 0.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain TrwB_AAD_bind PF10412.9 EMT51844.1 - 0.0028 16.6 0.3 0.005 15.8 0.3 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 EMT51844.1 - 0.004 17.1 0.1 0.0072 16.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_10 PF12846.7 EMT51844.1 - 0.005 15.8 0.4 0.022 13.7 0.1 1.9 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.23 EMT51844.1 - 0.0061 16.6 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EMT51844.1 - 0.0073 16.6 0.4 0.62 10.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMT51844.1 - 0.014 15.1 2.4 0.078 12.7 2.4 2.1 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMT51844.1 - 0.037 13.3 0.1 0.064 12.5 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin BCA_ABC_TP_C PF12399.8 EMT51844.1 - 0.042 13.8 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter AAA_16 PF13191.6 EMT51844.1 - 0.057 13.8 0.0 0.08 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EMT51844.1 - 0.075 13.5 0.3 0.34 11.3 0.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MukB PF04310.12 EMT51844.1 - 0.093 12.5 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 MukB N-terminal AAA_24 PF13479.6 EMT51844.1 - 0.11 12.2 0.1 0.71 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 EMT51844.1 - 0.14 11.8 0.3 0.48 10.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMT51844.1 - 0.18 11.9 0.3 0.43 10.7 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMT51844.1 - 0.23 11.8 3.2 0.84 10.0 3.2 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMT51845.1 - 6.9e-32 110.8 0.0 9.1e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 EMT51845.1 - 2e-13 49.9 0.1 4.8e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 EMT51845.1 - 2.8e-07 30.6 1.4 0.0049 16.7 0.3 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMT51845.1 - 0.00042 20.6 0.2 0.044 14.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EMT51845.1 - 0.00043 20.9 1.0 0.00056 20.5 1.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT51845.1 - 0.0014 18.4 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EMT51845.1 - 0.0035 16.8 0.1 0.037 13.5 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT51845.1 - 0.0041 16.9 0.2 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EMT51845.1 - 0.0076 16.0 0.1 0.027 14.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EMT51845.1 - 0.014 15.2 0.1 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EMT51845.1 - 0.018 14.5 0.7 0.66 9.5 0.1 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA PF00004.29 EMT51845.1 - 0.034 14.6 0.1 8.6 6.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT51845.1 - 0.043 14.2 0.0 0.092 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 EMT51845.1 - 0.069 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EMT51845.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EMT51845.1 - 0.11 12.1 0.3 3.4 7.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EMT51845.1 - 0.11 12.5 0.2 0.37 10.9 0.2 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase BPD_transp_2 PF02653.16 EMT51846.1 - 3.6e-49 167.3 28.4 3.6e-49 167.3 28.4 1.9 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component ASFV_J13L PF05568.11 EMT51846.1 - 0.49 10.1 1.6 0.56 9.9 0.0 1.8 2 0 0 2 2 2 0 African swine fever virus J13L protein BPD_transp_2 PF02653.16 EMT51847.1 - 1.5e-46 158.7 38.1 1.8e-46 158.5 38.1 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component NDUF_B12 PF08122.12 EMT51847.1 - 0.038 14.0 4.0 2.6 8.2 0.1 3.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Adenine_deam_C PF13382.6 EMT51848.1 - 1.6e-31 108.9 0.0 2.4e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 EMT51848.1 - 6e-13 48.8 0.1 8.7e-12 45.0 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMT51848.1 - 3.8e-09 36.5 0.1 9.5e-06 25.3 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF2892 PF11127.8 EMT51849.1 - 4.4e-15 55.5 0.6 7.1e-15 54.8 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) COX14 PF14880.6 EMT51850.1 - 0.0072 16.2 0.1 0.0085 15.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly FeoB_associated PF12669.7 EMT51850.1 - 0.0098 16.3 0.3 0.013 15.9 0.3 1.2 1 0 0 1 1 1 1 FeoB-associated Cys-rich membrane protein NVEALA PF14055.6 EMT51850.1 - 0.048 13.7 0.2 0.055 13.5 0.2 1.1 1 0 0 1 1 1 0 NVEALA protein MarR PF01047.22 EMT51851.1 - 9.2e-12 44.7 0.1 1.4e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EMT51851.1 - 6.8e-10 38.7 0.3 1.1e-09 38.0 0.3 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EMT51851.1 - 5e-06 26.9 0.1 8.1e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EMT51851.1 - 0.00015 21.3 0.7 0.00031 20.2 0.7 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EMT51851.1 - 0.0022 17.9 0.0 0.004 17.0 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MOZART1 PF12554.8 EMT51851.1 - 0.016 15.0 0.4 0.29 10.9 0.1 2.8 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated NIR_SIR_ferr PF03460.17 EMT51851.1 - 0.033 14.0 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain GatB_Yqey PF02637.18 EMT51851.1 - 0.043 13.7 0.2 0.26 11.2 0.2 2.1 1 1 0 1 1 1 0 GatB domain HTH_45 PF14947.6 EMT51851.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_IclR PF09339.10 EMT51851.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_23 PF13384.6 EMT51851.1 - 0.1 12.4 0.2 2.2 8.2 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain Glyco_transf_34 PF05637.12 EMT51851.1 - 0.13 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family MFS_1 PF07690.16 EMT51852.1 - 3.9e-38 131.3 45.9 1.2e-22 80.3 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT51852.1 - 7.1e-10 38.3 26.4 2.3e-07 30.0 9.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter PTR2 PF00854.21 EMT51852.1 - 1.5e-05 24.1 6.4 1.5e-05 24.1 6.4 3.3 4 0 0 4 4 4 1 POT family MFS_1_like PF12832.7 EMT51852.1 - 4e-05 22.6 28.0 0.0036 16.2 9.5 2.4 1 1 1 2 2 2 2 MFS_1 like family TssN PF17555.2 EMT51852.1 - 0.00027 20.4 1.3 0.00027 20.4 1.3 2.4 2 0 0 2 2 2 1 Type VI secretion system, TssN MFS_3 PF05977.13 EMT51852.1 - 0.017 13.5 19.9 0.17 10.3 0.7 2.8 2 1 0 2 2 2 0 Transmembrane secretion effector PUCC PF03209.15 EMT51852.1 - 0.022 13.8 23.2 0.086 11.8 3.1 2.4 2 0 0 2 2 2 0 PUCC protein MFS_4 PF06779.14 EMT51852.1 - 0.03 13.6 25.0 0.45 9.7 12.1 2.2 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB DUF2148 PF09918.9 EMT51852.1 - 0.11 12.6 0.2 0.29 11.2 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) GARS_A PF01071.19 EMT51853.1 - 5.7e-82 274.2 0.1 7.7e-82 273.8 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EMT51853.1 - 1.1e-35 122.3 0.0 4.7e-35 120.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EMT51853.1 - 3.8e-33 113.6 2.2 8.4e-32 109.3 0.5 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_3 PF02655.14 EMT51853.1 - 2e-06 28.0 0.0 4.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EMT51853.1 - 7.9e-06 25.5 0.1 1.5e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EMT51853.1 - 0.00034 20.2 0.0 0.00069 19.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EMT51853.1 - 0.00054 19.6 0.0 0.0009 18.9 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 EMT51853.1 - 0.049 13.2 0.1 0.084 12.4 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain PGM1_C PF18105.1 EMT51853.1 - 0.068 12.7 4.4 2.6 7.6 0.1 2.6 2 0 0 2 2 2 0 PGM1 C-terminal domain ATP-grasp_5 PF13549.6 EMT51853.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain AICARFT_IMPCHas PF01808.18 EMT51854.1 - 5.5e-120 400.3 0.9 6.9e-120 400.0 0.9 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EMT51854.1 - 2.6e-30 104.4 0.0 6.2e-30 103.3 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain PrpR_N PF06506.11 EMT51854.1 - 0.045 13.3 0.2 0.36 10.4 0.1 2.5 2 1 0 2 2 2 0 Propionate catabolism activator Sigma70_r1_1 PF03979.14 EMT51855.1 - 0.0076 16.3 0.3 0.014 15.5 0.2 1.6 1 1 0 1 1 1 1 Sigma-70 factor, region 1.1 AHSA1 PF08327.11 EMT51856.1 - 9.8e-19 67.8 0.3 1.1e-18 67.6 0.3 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EMT51856.1 - 1.3e-05 25.5 0.2 1.6e-05 25.2 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Sigma70_r2 PF04542.14 EMT51857.1 - 1.3e-12 47.3 0.1 2.3e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT51857.1 - 4.8e-09 35.7 0.1 9.4e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT51857.1 - 1.1e-05 24.9 0.1 2.3e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Formyl_trans_N PF00551.19 EMT51859.1 - 4.8e-57 192.6 0.0 5.6e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase AIRS_C PF02769.22 EMT51860.1 - 6.2e-36 123.9 0.1 1.4e-35 122.8 0.0 1.6 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EMT51860.1 - 8.4e-18 64.8 1.8 2e-17 63.6 1.3 1.8 1 1 1 2 2 2 1 AIR synthase related protein, N-terminal domain GATase_7 PF13537.6 EMT51861.1 - 1.1e-22 80.2 0.0 2.4e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EMT51861.1 - 1.6e-21 76.9 0.0 5e-21 75.3 0.1 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EMT51861.1 - 1.4e-07 30.7 0.0 2.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Pribosyltran PF00156.27 EMT51861.1 - 9.5e-07 28.5 0.4 1.8e-06 27.6 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_2 PF00310.21 EMT51861.1 - 1.1e-05 24.4 0.1 0.03 13.0 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II AIRS_C PF02769.22 EMT51862.1 - 3.1e-57 193.1 11.6 3.9e-35 121.3 2.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EMT51862.1 - 5.9e-54 180.7 2.3 2.3e-26 92.3 0.3 2.5 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain FGAR-AT_linker PF18072.1 EMT51862.1 - 5.9e-17 61.9 0.1 1.3e-16 60.9 0.1 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain GATase_5 PF13507.6 EMT51863.1 - 4e-47 160.5 0.0 5.4e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EMT51863.1 - 6.2e-09 35.9 0.0 9.6e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 EMT51863.1 - 5e-08 32.8 0.0 1.4e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EMT51863.1 - 7.8e-06 25.8 0.0 1.4e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I ThiJ_like PF17124.5 EMT51863.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like Glyco_hydro_42M PF08532.10 EMT51863.1 - 0.057 12.9 0.0 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain SNO PF01174.19 EMT51863.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 SNO glutamine amidotransferase family PurS PF02700.14 EMT51864.1 - 2e-34 117.6 0.1 2.2e-34 117.5 0.1 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase Fe_hyd_lg_C PF02906.14 EMT51864.1 - 0.025 14.2 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain SAICAR_synt PF01259.18 EMT51865.1 - 4.3e-70 236.2 0.0 4.9e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase MCPsignal PF00015.21 EMT51866.1 - 7.3e-31 107.3 24.5 1.6e-30 106.2 9.8 3.5 1 1 2 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 EMT51866.1 - 8.9e-10 38.8 0.1 5.3e-09 36.3 0.1 2.5 1 0 0 1 1 1 1 HAMP domain DUF948 PF06103.11 EMT51866.1 - 5.6e-05 23.3 12.6 0.65 10.3 0.1 5.6 1 1 2 5 5 5 2 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 EMT51866.1 - 0.0035 17.4 14.8 0.069 13.2 0.7 3.9 2 2 2 4 4 4 2 Laminin Domain II DUF745 PF05335.13 EMT51866.1 - 0.0056 16.4 0.4 0.0056 16.4 0.4 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF745) Baculo_PEP_C PF04513.12 EMT51866.1 - 0.0097 16.0 12.6 0.015 15.4 0.6 4.3 3 2 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus T7SS_ESX_EspC PF10824.8 EMT51866.1 - 0.056 13.9 14.4 0.29 11.6 2.1 4.0 4 1 1 5 5 5 0 Excreted virulence factor EspC, type VII ESX diderm NPV_P10 PF05531.12 EMT51866.1 - 0.09 13.3 2.1 33 5.0 0.2 4.3 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DASH_Dad2 PF08654.10 EMT51866.1 - 0.39 11.2 11.5 2.7 8.5 0.1 4.4 3 1 2 6 6 5 0 DASH complex subunit Dad2 WXG100 PF06013.12 EMT51866.1 - 0.44 10.8 12.0 5.6 7.3 0.1 5.3 2 2 0 4 4 4 0 Proteins of 100 residues with WXG Pup PF05639.11 EMT51866.1 - 0.47 11.4 2.9 3.5 8.6 0.0 3.0 2 1 0 2 2 2 0 Pup-like protein Dynactin_p22 PF07426.11 EMT51866.1 - 0.55 10.1 0.0 0.55 10.1 0.0 4.1 4 2 1 5 5 5 0 Dynactin subunit p22 DUF1664 PF07889.12 EMT51866.1 - 0.62 10.1 19.6 3.5 7.7 2.6 5.0 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 EMT51866.1 - 0.78 7.6 7.6 3.3 5.5 7.6 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.9 EMT51866.1 - 0.94 9.8 16.0 6.5 7.1 0.8 5.0 3 2 2 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Flg_hook PF02120.16 EMT51866.1 - 0.94 9.4 4.6 16 5.5 0.1 3.2 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK TACC_C PF05010.14 EMT51866.1 - 1.2 8.9 19.6 0.78 9.5 3.7 3.5 3 1 1 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Vps53_N PF04100.12 EMT51866.1 - 1.2 8.0 12.5 1.4 7.8 0.5 2.8 2 1 1 3 3 3 0 Vps53-like, N-terminal DisA-linker PF10635.9 EMT51866.1 - 2.4 7.9 9.1 0.046 13.5 0.7 2.5 3 0 0 3 3 3 0 DisA bacterial checkpoint controller linker region Sec20 PF03908.13 EMT51866.1 - 2.9 7.9 11.5 4.2 7.3 0.5 4.4 3 1 0 4 4 4 0 Sec20 COG2 PF06148.11 EMT51866.1 - 3.2 7.9 20.8 0.77 9.9 0.5 4.6 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 DegS PF05384.11 EMT51866.1 - 5.7 6.4 11.8 0.84 9.1 0.3 3.9 2 2 3 5 5 5 0 Sensor protein DegS Filament PF00038.21 EMT51866.1 - 6.5 6.2 22.5 0.21 11.1 4.9 3.1 3 1 0 3 3 3 0 Intermediate filament protein IFT57 PF10498.9 EMT51866.1 - 7.4 5.4 12.3 1 8.3 2.1 3.1 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Allexi_40kDa PF05549.11 EMT51866.1 - 8.6 5.8 9.3 4.1 6.8 1.2 3.3 1 1 2 3 3 3 0 Allexivirus 40kDa protein Lactamase_B PF00753.27 EMT51867.1 - 7.5e-37 127.2 2.0 9.6e-37 126.9 2.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMT51867.1 - 3e-07 30.2 0.1 4.3e-07 29.6 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HupF_HypC PF01455.18 EMT51867.1 - 0.024 14.8 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 HupF/HypC family Fe-ADH PF00465.19 EMT51869.1 - 1.5e-103 346.4 0.4 1.9e-103 346.1 0.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMT51869.1 - 8.2e-19 68.3 1.6 5.1e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase rve_3 PF13683.6 EMT51869.1 - 0.096 12.5 0.0 7.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain PGM_PMM_II PF02879.16 EMT51869.1 - 0.15 12.7 0.0 0.45 11.2 0.0 1.8 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Peptidase_M29 PF02073.15 EMT51870.1 - 2.4e-52 178.1 0.0 2.8e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) DUF169 PF02596.15 EMT51871.1 - 5.3e-51 173.5 0.0 6.3e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ArCR, COG2043 PepSY PF03413.19 EMT51872.1 - 0.0059 17.1 0.4 0.03 14.9 0.1 2.1 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain LPAM_2 PF13627.6 EMT51872.1 - 0.042 13.7 1.2 0.073 12.9 1.2 1.3 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site G_glu_transpept PF01019.21 EMT51873.1 - 3.8e-160 534.0 0.0 4.3e-160 533.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Chromate_transp PF02417.15 EMT51874.1 - 8.2e-34 117.0 14.7 9.4e-34 116.8 14.7 1.0 1 0 0 1 1 1 1 Chromate transporter Abhydrolase_1 PF00561.20 EMT51874.1 - 0.051 13.2 0.0 0.069 12.8 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold TctB PF07331.11 EMT51874.1 - 0.23 11.7 12.4 0.37 11.1 12.4 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF3487 PF11990.8 EMT51874.1 - 0.43 10.5 10.8 0.72 9.8 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Chromate_transp PF02417.15 EMT51875.1 - 6.3e-39 133.6 11.5 7.7e-39 133.3 11.5 1.0 1 0 0 1 1 1 1 Chromate transporter SUR7 PF06687.12 EMT51875.1 - 0.021 14.5 0.3 0.028 14.0 0.3 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF4191 PF13829.6 EMT51875.1 - 0.42 9.9 5.0 0.55 9.5 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2304 PF10066.9 EMT51875.1 - 1.2 9.4 5.2 0.39 10.9 1.9 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) FeoB_associated PF12669.7 EMT51875.1 - 4.2 7.9 4.5 9.3 6.7 0.0 3.3 4 0 0 4 4 4 0 FeoB-associated Cys-rich membrane protein DUF3099 PF11298.8 EMT51875.1 - 4.5 7.5 6.6 32 4.8 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) DUF1772 PF08592.11 EMT51875.1 - 7.4 6.9 10.3 45 4.3 8.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF4006 PF13179.6 EMT51875.1 - 7.8 6.5 7.8 18 5.4 0.6 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF4006) HTH_AsnC-type PF13404.6 EMT51876.1 - 1.5e-12 47.2 0.0 2.5e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 EMT51876.1 - 3.6e-12 46.1 0.1 6.2e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 EMT51876.1 - 8.5e-09 34.8 0.0 1.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 EMT51876.1 - 0.0015 17.9 0.0 0.0036 16.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 EMT51876.1 - 0.0026 17.4 0.1 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Mga PF08280.11 EMT51876.1 - 0.0032 17.5 0.0 0.01 15.9 0.0 1.8 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_11 PF08279.12 EMT51876.1 - 0.0032 17.4 0.1 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 HTH domain Sigma70_r4 PF04545.16 EMT51876.1 - 0.0057 16.2 0.0 0.018 14.5 0.0 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_20 PF12840.7 EMT51876.1 - 0.0057 16.7 0.0 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.19 EMT51876.1 - 0.0057 16.2 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 EMT51876.1 - 0.0065 16.2 0.2 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain Rho_N PF07498.12 EMT51876.1 - 0.013 15.4 0.2 0.094 12.7 0.1 2.3 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain MarR_2 PF12802.7 EMT51876.1 - 0.036 14.0 0.1 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 MarR family HTH_1 PF00126.27 EMT51876.1 - 0.065 13.2 0.5 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family SgrR_N PF12793.7 EMT51876.1 - 0.1 12.8 0.2 0.53 10.5 0.2 2.0 1 1 0 1 1 1 0 Sugar transport-related sRNA regulator N-term HTH_28 PF13518.6 EMT51876.1 - 0.11 12.7 0.1 0.57 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TPR_4 PF07721.14 EMT51876.1 - 1.2 10.0 4.3 0.45 11.3 1.5 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat FtsX PF02687.21 EMT51877.1 - 3.5e-13 49.8 16.6 2.3e-12 47.2 4.5 6.2 6 1 0 6 6 6 2 FtsX-like permease family Sid-5 PF17204.3 EMT51877.1 - 0.043 14.0 0.2 0.27 11.4 0.2 2.4 1 0 0 1 1 1 0 Sid-5 family ABC_tran PF00005.27 EMT51878.1 - 1.5e-36 125.9 0.0 2.1e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT51878.1 - 2.6e-05 24.2 0.3 0.17 11.6 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMT51878.1 - 0.00038 21.0 1.0 0.00066 20.2 0.9 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT51878.1 - 0.00042 20.0 0.2 0.001 18.8 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMT51878.1 - 0.00075 19.4 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EMT51878.1 - 0.00091 18.7 0.7 0.015 14.8 0.7 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMT51878.1 - 0.0019 18.6 0.0 0.0024 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT51878.1 - 0.0061 16.8 0.2 0.079 13.2 0.0 2.4 2 1 1 3 3 3 1 AAA domain cobW PF02492.19 EMT51878.1 - 0.0098 15.5 0.2 0.022 14.4 0.1 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 EMT51878.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 EMT51878.1 - 0.022 14.5 0.2 0.043 13.5 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMT51878.1 - 0.023 14.3 0.3 0.43 10.1 0.2 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EMT51878.1 - 0.031 14.6 1.1 0.4 11.0 1.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EMT51878.1 - 0.039 13.7 0.1 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 EMT51878.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 EMT51878.1 - 0.059 12.4 0.1 0.092 11.8 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EMT51878.1 - 0.061 13.6 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EMT51878.1 - 0.07 12.3 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 EMT51878.1 - 0.094 12.8 0.7 0.17 12.0 0.7 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EMT51878.1 - 0.097 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EMT51878.1 - 0.12 12.6 0.0 1.5 9.1 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF4088 PF13317.6 EMT51878.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) NACHT PF05729.12 EMT51878.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 EMT51878.1 - 0.16 12.5 0.6 0.36 11.4 0.4 1.7 1 1 0 2 2 2 0 AAA domain HATPase_c PF02518.26 EMT51879.1 - 2.3e-18 66.8 0.0 3.4e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT51879.1 - 2.7e-05 24.1 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HisKA PF00512.25 EMT51879.1 - 0.006 16.6 0.1 0.018 15.1 0.1 1.8 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF2070 PF09843.9 EMT51879.1 - 0.016 13.5 0.1 0.021 13.1 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YbhQ PF11076.8 EMT51879.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ SpoIISA_toxin PF14171.6 EMT51879.1 - 0.02 14.6 1.6 0.036 13.8 1.6 1.5 1 1 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system HATPase_c_3 PF13589.6 EMT51879.1 - 0.02 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phage_holin_3_6 PF07332.11 EMT51879.1 - 0.15 12.1 0.9 0.34 11.0 0.9 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Response_reg PF00072.24 EMT51880.1 - 3.8e-25 88.2 0.0 6e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT51880.1 - 1.8e-23 82.4 1.3 3.6e-23 81.4 0.5 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Sigma70_r2 PF04542.14 EMT51881.1 - 5.8e-17 61.2 2.2 7.5e-17 60.9 1.4 1.6 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EMT51881.1 - 3.1e-11 42.6 0.2 7.1e-11 41.5 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EMT51881.1 - 2.2e-09 36.8 0.0 3.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 EMT51881.1 - 0.00029 20.5 0.0 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0122 PF04297.14 EMT51881.1 - 0.00078 19.6 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_ECF PF07638.11 EMT51881.1 - 0.0014 18.6 0.2 0.0028 17.6 0.2 1.6 1 1 0 1 1 1 1 ECF sigma factor Peptidase_M1 PF01433.20 EMT51882.1 - 3.4e-08 33.3 0.3 6.7e-08 32.4 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain FtsX PF02687.21 EMT51882.1 - 0.00011 22.6 9.6 0.00011 22.6 9.6 4.4 4 2 0 4 4 4 2 FtsX-like permease family DUF21 PF01595.20 EMT51882.1 - 5.4 6.7 10.1 6.2 6.5 0.2 3.3 3 1 1 4 4 4 0 Cyclin M transmembrane N-terminal domain ABC_tran PF00005.27 EMT51883.1 - 2.7e-34 118.6 0.0 3.9e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT51883.1 - 5.1e-08 32.6 0.0 0.0032 17.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT51883.1 - 1.6e-07 31.4 0.2 0.00032 20.6 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT51883.1 - 7.4e-06 25.6 0.1 1.7e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT51883.1 - 7.9e-05 23.2 0.2 0.00012 22.6 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMT51883.1 - 0.0004 20.7 0.0 0.0017 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EMT51883.1 - 0.0015 18.5 0.1 0.0029 17.5 0.0 1.5 2 0 0 2 2 1 1 RsgA GTPase AAA_15 PF13175.6 EMT51883.1 - 0.0036 17.1 0.0 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 EMT51883.1 - 0.0069 16.8 0.1 0.01 16.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EMT51883.1 - 0.024 15.2 0.0 0.31 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EMT51883.1 - 0.027 14.2 0.0 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EMT51883.1 - 0.038 14.1 0.2 0.12 12.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMT51883.1 - 0.041 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EMT51883.1 - 0.073 13.2 0.0 0.66 10.1 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 EMT51883.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 EMT51883.1 - 0.13 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EMT51883.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Thioredoxin PF00085.20 EMT51884.1 - 2.1e-06 27.7 0.1 7.9e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EMT51884.1 - 2.2e-06 27.6 0.1 1e-05 25.5 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 EMT51884.1 - 1.4e-05 25.5 0.0 2.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMT51884.1 - 1.6e-05 25.1 0.4 0.0028 18.0 0.1 3.0 2 1 0 2 2 2 1 Thioredoxin-like TraF PF13728.6 EMT51884.1 - 0.00087 19.2 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 EMT51884.1 - 0.0036 17.5 0.0 0.24 11.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 EMT51884.1 - 0.0076 16.0 0.1 0.031 14.0 0.1 1.8 1 1 0 1 1 1 1 Redoxin Toxin-deaminase PF14424.6 EMT51884.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases DUF836 PF05768.14 EMT51884.1 - 0.025 15.0 0.1 0.039 14.4 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TMEM154 PF15102.6 EMT51884.1 - 0.031 14.2 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family GSHPx PF00255.19 EMT51884.1 - 0.044 13.4 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione peroxidase Thioredoxin_9 PF14595.6 EMT51884.1 - 0.06 13.1 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin MauE PF07291.11 EMT51885.1 - 3.7e-22 79.0 4.9 3.7e-22 79.0 4.9 1.5 1 1 1 2 2 2 1 Methylamine utilisation protein MauE DoxX PF07681.12 EMT51885.1 - 1e-08 35.6 7.1 1e-08 35.6 7.1 2.3 2 1 0 2 2 2 1 DoxX ABC_tran PF00005.27 EMT51886.1 - 2.9e-34 118.5 0.0 4.9e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EMT51886.1 - 4.2e-10 39.7 5.4 7.5e-10 38.9 5.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 EMT51886.1 - 6.7e-08 32.7 0.4 0.0032 17.3 0.1 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT51886.1 - 3.4e-06 26.7 0.4 0.00063 19.2 0.4 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMT51886.1 - 0.00038 21.0 0.0 0.0009 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT51886.1 - 0.00061 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EMT51886.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ABC_ATPase PF09818.9 EMT51886.1 - 0.0022 16.9 0.1 1.3 7.8 0.0 2.9 2 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 EMT51886.1 - 0.0025 17.6 0.0 0.0097 15.6 0.0 1.7 1 1 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 EMT51886.1 - 0.012 14.7 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_13 PF13166.6 EMT51886.1 - 0.017 13.8 0.1 0.043 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EMT51886.1 - 0.017 15.4 0.0 0.18 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EMT51886.1 - 0.032 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMT51886.1 - 0.034 14.1 0.5 0.11 12.4 0.2 2.0 3 0 0 3 3 1 0 NACHT domain AAA_5 PF07728.14 EMT51886.1 - 0.041 13.9 0.0 0.27 11.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.21 EMT51886.1 - 0.045 13.4 0.0 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase GTP_EFTU PF00009.27 EMT51886.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EMT51886.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 EMT51886.1 - 0.062 13.7 0.1 0.53 10.7 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 EMT51886.1 - 0.068 13.4 0.2 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EMT51886.1 - 0.074 13.4 0.0 0.21 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EMT51886.1 - 0.16 11.3 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AhpC-TSA PF00578.21 EMT51887.1 - 0.00014 21.7 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 EMT51887.1 - 0.00018 21.9 0.1 0.00032 21.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMT51887.1 - 0.0011 19.3 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EMT51887.1 - 0.0038 16.9 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin SNAD4 PF18750.1 EMT51887.1 - 0.073 13.2 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 TraF PF13728.6 EMT51887.1 - 0.12 12.1 0.0 0.51 10.1 0.0 1.8 1 1 0 1 1 1 0 F plasmid transfer operon protein APOBEC2 PF18772.1 EMT51887.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 Lyase_1 PF00206.20 EMT51888.1 - 3.5e-79 266.4 0.0 5.8e-79 265.7 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EMT51888.1 - 2.5e-28 98.4 0.1 6.8e-28 97.0 0.1 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus HTH_39 PF14090.6 EMT51888.1 - 0.043 13.6 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain ATP-grasp PF02222.22 EMT51889.1 - 3.9e-61 205.6 0.0 6.1e-61 204.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EMT51889.1 - 1.3e-17 63.2 0.0 2.3e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EMT51889.1 - 8.9e-10 38.4 0.0 6.4e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 EMT51889.1 - 4.3e-06 26.4 0.0 6.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 EMT51889.1 - 0.00023 20.6 0.0 0.00038 19.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-grasp_5 PF13549.6 EMT51889.1 - 0.00053 19.5 0.1 0.0012 18.3 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EMT51889.1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRC PF00731.20 EMT51890.1 - 1.4e-66 222.6 0.6 1.5e-66 222.5 0.6 1.0 1 0 0 1 1 1 1 AIR carboxylase Peptidase_M1 PF01433.20 EMT51891.1 - 1e-20 74.2 0.0 1e-20 74.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M1 domain Death PF00531.22 EMT51891.1 - 0.053 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Death domain DUF4402 PF14352.6 EMT51891.1 - 0.12 13.1 2.7 0.37 11.5 2.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4402) EBP50_C PF09007.11 EMT51891.1 - 0.22 12.5 4.8 0.62 11.1 4.8 1.7 1 0 0 1 1 1 0 EBP50, C-terminal Peptidase_M1 PF01433.20 EMT51892.1 - 8.9e-19 67.9 0.1 1.5e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain DUF1570 PF07607.11 EMT51892.1 - 0.0065 16.8 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1570) tRNA-synt_His PF13393.6 EMT51893.1 - 4.3e-13 49.2 0.4 6.2e-13 48.7 0.4 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EMT51893.1 - 8.1e-10 38.7 0.1 1.4e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.6 EMT51894.1 - 6e-29 101.3 0.0 7.1e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 EMT51894.1 - 5e-08 33.1 0.0 6.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EMT51894.1 - 0.002 17.7 0.0 0.0027 17.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 EMT51894.1 - 0.02 14.0 0.0 0.26 10.3 0.0 2.1 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) Xan_ur_permease PF00860.20 EMT51895.1 - 1.2e-42 146.0 45.9 1.9e-42 145.3 45.9 1.3 1 0 0 1 1 1 1 Permease family TraL PF07178.11 EMT51895.1 - 0.038 14.4 0.2 0.038 14.4 0.2 4.6 4 2 0 4 4 4 0 TraL protein GMP_synt_C PF00958.22 EMT51896.1 - 7.9e-46 154.1 0.2 1.7e-45 153.0 0.2 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EMT51896.1 - 3.7e-43 147.5 0.0 5.6e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EMT51896.1 - 1.1e-11 44.9 0.1 4.2e-11 43.0 0.0 2.1 3 0 0 3 3 3 1 Peptidase C26 NAD_synthase PF02540.17 EMT51896.1 - 1.2e-11 44.2 0.1 9.6e-07 28.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.16 EMT51896.1 - 1e-05 24.5 0.1 6.9e-05 21.8 0.0 2.2 3 0 0 3 3 3 1 tRNA methyl transferase Asn_synthase PF00733.21 EMT51896.1 - 3.9e-05 23.5 0.0 9.7e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.13 EMT51896.1 - 0.00016 21.3 0.0 0.0067 15.9 0.0 2.2 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 EMT51896.1 - 0.00059 19.7 0.0 0.00086 19.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family ThiI PF02568.14 EMT51896.1 - 0.0022 17.6 0.1 0.0043 16.7 0.1 1.6 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 EMT51896.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 EMT51896.1 - 0.029 14.4 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family SpoVAE PF14097.6 EMT51896.1 - 0.057 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AE1 Transglut_core PF01841.19 EMT51897.1 - 6e-31 107.2 0.0 1.8e-30 105.7 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF4129 PF13559.6 EMT51897.1 - 1.7e-07 31.4 0.2 3.9e-07 30.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) DUF5493 PF17597.2 EMT51897.1 - 0.18 12.1 2.2 0.37 11.1 1.7 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5493) Transglut_core3 PF13471.6 EMT51897.1 - 1.2 9.1 4.2 0.6 10.0 0.3 2.4 2 1 0 2 2 2 0 Transglutaminase-like superfamily DUF58 PF01882.18 EMT51898.1 - 1.7e-21 76.3 0.2 3.4e-21 75.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF58 AAA_3 PF07726.11 EMT51899.1 - 2.5e-66 221.5 0.0 3.8e-66 220.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EMT51899.1 - 1.3e-21 76.2 0.2 2.5e-21 75.3 0.2 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 EMT51899.1 - 1.9e-14 53.8 0.0 3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EMT51899.1 - 2.1e-06 28.2 0.0 6.1e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 EMT51899.1 - 1.5e-05 24.2 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain RuvB_N PF05496.12 EMT51899.1 - 0.00012 21.8 0.0 0.00071 19.4 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EMT51899.1 - 0.00036 20.3 0.0 0.029 14.1 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EMT51899.1 - 0.0022 17.4 0.1 0.44 9.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EMT51899.1 - 0.0096 16.3 0.0 0.022 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain MCM_lid PF17855.1 EMT51899.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 MCM AAA-lid domain Transposase_mut PF00872.18 EMT51900.1 - 1.7e-30 106.2 0.3 1.8e-30 106.1 0.3 1.0 1 0 0 1 1 1 1 Transposase, Mutator family SRP68 PF16969.5 EMT51900.1 - 0.017 14.2 0.1 0.017 14.2 0.1 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 TssO PF17561.2 EMT51900.1 - 0.1 12.7 3.5 0.08 13.0 1.8 1.6 2 0 0 2 2 2 0 Type VI secretion system, TssO Ish1 PF10281.9 EMT51900.1 - 0.11 12.8 0.1 0.39 11.1 0.1 2.1 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein HTH_23 PF13384.6 EMT51900.1 - 0.19 11.5 0.2 1.9 8.4 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain OCD_Mu_crystall PF02423.15 EMT51902.1 - 5.7e-75 252.2 5.1 1.2e-41 142.7 2.4 2.0 1 1 1 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EMT51902.1 - 1.6e-11 44.4 0.1 8.6e-06 25.9 0.0 2.5 1 1 1 2 2 2 2 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 EMT51902.1 - 1.2e-05 24.7 0.4 3.3e-05 23.3 0.5 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TPP_enzyme_C PF02775.21 EMT51902.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Aminotran_1_2 PF00155.21 EMT51903.1 - 6.2e-39 134.2 0.0 7.4e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMT51903.1 - 6.4e-08 31.9 0.0 9.6e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.7 EMT51903.1 - 1.3e-05 24.2 0.0 0.00016 20.6 0.0 2.0 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 EMT51903.1 - 3.4e-05 22.6 0.0 4.7e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EMT51903.1 - 0.00015 21.2 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EMT51903.1 - 0.0045 16.4 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3447 PF11929.8 EMT51903.1 - 0.26 11.2 1.2 1 9.4 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) DcuC PF03606.15 EMT51904.1 - 3.4e-113 378.6 43.4 4.2e-113 378.3 43.4 1.0 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier ABG_transport PF03806.13 EMT51904.1 - 1.7e-07 29.8 15.9 1.7e-07 29.8 15.9 2.3 2 0 0 2 2 2 2 AbgT putative transporter family Fungus-induced PF10917.8 EMT51904.1 - 0.44 10.9 4.3 21 5.6 0.5 3.4 2 0 0 2 2 2 0 Fungus-induced protein CitMHS PF03600.16 EMT51904.1 - 5.1 6.2 56.3 77 2.3 34.4 2.4 1 1 1 2 2 2 0 Citrate transporter DUF5383 PF17355.2 EMT51904.1 - 5.9 7.3 6.7 0.58 10.5 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5383) Peptidase_M20 PF01546.28 EMT51905.1 - 2.2e-29 102.7 0.7 2.7e-29 102.4 0.7 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT51905.1 - 4.4e-12 45.9 0.8 7.5e-12 45.1 0.2 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT51905.1 - 0.0036 17.0 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PALP PF00291.25 EMT51906.1 - 1.4e-81 274.2 5.9 1.6e-81 274.0 5.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ApoO PF09769.9 EMT51906.1 - 0.059 13.3 0.1 7.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein O MR_MLE_C PF13378.6 EMT51907.1 - 1.6e-52 178.2 3.7 2.4e-52 177.7 3.7 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EMT51907.1 - 2e-22 79.6 0.0 5.2e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EMT51907.1 - 0.0036 16.5 0.1 0.0062 15.7 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus LysR_substrate PF03466.20 EMT51908.1 - 2.7e-33 115.1 0.0 3.7e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT51908.1 - 1.5e-20 72.9 0.2 3.2e-20 71.8 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EMT51908.1 - 0.0086 15.9 0.2 0.019 14.7 0.2 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 EMT51908.1 - 0.12 12.5 0.0 0.43 10.7 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Abhydrolase_1 PF00561.20 EMT51909.1 - 2.1e-21 76.7 0.2 1.9e-16 60.5 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMT51909.1 - 1.6e-18 66.9 0.1 8.1e-18 64.6 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMT51909.1 - 7.3e-17 62.7 0.0 9.5e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EMT51909.1 - 0.00027 21.1 0.0 0.00038 20.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF1057 PF06342.12 EMT51909.1 - 0.0055 15.8 0.0 0.0072 15.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.14 EMT51909.1 - 0.11 11.2 0.0 0.54 8.9 0.0 1.9 2 0 0 2 2 2 0 Ndr family Peptidase_S9 PF00326.21 EMT51909.1 - 0.14 11.6 0.0 4.1 6.8 0.0 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family ROK PF00480.20 EMT51910.1 - 1.7e-45 155.8 0.0 2.3e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 ROK family HTH_24 PF13412.6 EMT51910.1 - 0.00068 19.1 0.2 0.0015 18.0 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EMT51910.1 - 0.0038 17.1 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EMT51910.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 MarR family DnaB_2 PF07261.11 EMT51910.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Replication initiation and membrane attachment FeoC PF09012.10 EMT51910.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_54 PF18607.1 EMT51910.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 ParA helix turn helix domain SBP_bac_6 PF13343.6 EMT51911.1 - 1.9e-38 132.2 3.5 2.4e-38 132.0 3.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EMT51911.1 - 1e-24 87.8 2.2 1.5e-24 87.3 2.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EMT51911.1 - 4.4e-20 72.4 0.0 6.1e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT51911.1 - 2.1e-15 57.5 6.8 5.3e-15 56.2 6.8 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 EMT51911.1 - 0.056 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain ABC_tran PF00005.27 EMT51912.1 - 4.9e-35 121.0 0.0 8e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 EMT51912.1 - 2.6e-08 33.9 0.1 1.8e-07 31.2 0.0 2.5 1 1 1 2 2 2 1 TOBE domain AAA_21 PF13304.6 EMT51912.1 - 5.9e-07 29.6 0.1 0.00023 21.1 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE PF03459.17 EMT51912.1 - 6.9e-07 29.5 0.6 0.009 16.3 0.2 2.8 2 1 0 2 2 2 2 TOBE domain AAA PF00004.29 EMT51912.1 - 0.018 15.5 0.5 0.079 13.4 0.5 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMT51912.1 - 0.019 15.2 0.1 0.042 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EMT51912.1 - 0.02 15.1 0.1 0.44 10.8 0.1 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EMT51912.1 - 0.029 14.3 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 EMT51912.1 - 0.034 14.7 1.0 0.062 13.8 1.0 1.5 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 EMT51912.1 - 0.038 13.4 0.6 0.3 10.5 0.6 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMT51912.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EMT51912.1 - 0.12 12.8 0.1 0.21 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EMT51912.1 - 0.14 11.6 0.7 0.63 9.4 0.4 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 EMT51912.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EMT51912.1 - 0.24 11.1 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain BPD_transp_1 PF00528.22 EMT51913.1 - 9.9e-34 116.7 46.1 8.6e-21 74.5 20.4 3.6 2 2 2 4 4 4 2 Binding-protein-dependent transport system inner membrane component SHR3_chaperone PF08229.11 EMT51913.1 - 0.085 11.8 2.7 0.13 11.3 0.5 2.3 1 1 1 2 2 2 0 ER membrane protein SH3 NPCBM_assoc PF10633.9 EMT51914.1 - 4.1e-25 87.8 12.9 6.3e-15 55.2 2.7 3.2 2 1 0 2 2 2 2 NPCBM-associated, NEW3 domain of alpha-galactosidase PIG-L PF02585.17 EMT51914.1 - 3.1e-15 57.0 0.0 9.1e-15 55.4 0.0 1.9 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF11 PF01345.18 EMT51914.1 - 0.00073 19.8 7.0 0.042 14.1 1.5 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF11 CARDB PF07705.11 EMT51914.1 - 0.0028 17.9 1.5 0.41 10.9 0.0 2.8 3 0 0 3 3 3 2 CARDB MG2 PF01835.19 EMT51914.1 - 0.077 13.5 0.2 2.9 8.4 0.1 2.7 2 0 0 2 2 2 0 MG2 domain Lyase_1 PF00206.20 EMT51915.1 - 5.2e-40 137.8 1.1 6.6e-40 137.4 0.2 1.6 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 EMT51915.1 - 5.4e-17 62.3 1.7 2e-16 60.5 0.8 2.4 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal BcrAD_BadFG PF01869.20 EMT51916.1 - 3.9e-40 138.0 2.4 4.7e-40 137.8 2.4 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 EMT51916.1 - 0.037 13.5 0.2 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 ROK family YdaT_toxin PF06254.11 EMT51916.1 - 0.12 13.0 0.0 0.42 11.2 0.0 1.9 2 0 0 2 2 2 0 Putative bacterial toxin ydaT PIG-L PF02585.17 EMT51917.1 - 3.4e-32 111.8 0.0 4.8e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Asp_Glu_race PF01177.22 EMT51918.1 - 1.8e-60 204.6 0.4 2e-60 204.4 0.4 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Pantoate_transf PF02548.15 EMT51918.1 - 9.5e-05 21.9 0.1 0.00019 20.9 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Peripla_BP_1 PF00532.21 EMT51918.1 - 0.045 13.2 0.1 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family Redoxin PF08534.10 EMT51918.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Redoxin LysR_substrate PF03466.20 EMT51919.1 - 2.1e-44 151.4 0.2 2.6e-44 151.1 0.2 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT51919.1 - 4e-21 74.7 0.0 9.3e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_34 PF13601.6 EMT51919.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain DinB_2 PF12867.7 EMT51920.1 - 2.5e-18 66.8 0.0 3.1e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 EMT51920.1 - 0.0001 22.3 0.0 0.00017 21.5 0.0 1.3 1 1 0 1 1 1 1 DinB family DUF664 PF04978.12 EMT51920.1 - 0.00039 20.9 0.0 0.00048 20.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF664) DUF1993 PF09351.10 EMT51920.1 - 0.097 12.8 0.0 0.18 11.9 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) HxlR PF01638.17 EMT51921.1 - 1.9e-35 120.6 0.3 2.5e-35 120.2 0.3 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.22 EMT51921.1 - 0.00027 20.8 0.0 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 EMT51921.1 - 0.035 14.2 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_45 PF14947.6 EMT51921.1 - 0.052 13.5 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DJ-1_PfpI PF01965.24 EMT51922.1 - 8.2e-35 120.0 0.4 9.1e-35 119.9 0.4 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family DAGK_cat PF00781.24 EMT51922.1 - 0.00076 19.1 0.8 0.0019 17.8 0.3 1.8 1 1 1 2 2 2 1 Diacylglycerol kinase catalytic domain Peptidase_S51 PF03575.17 EMT51922.1 - 0.002 17.8 0.2 0.0028 17.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase family S51 SBP_bac_6 PF13343.6 EMT51923.1 - 3.1e-36 125.0 0.6 5.1e-36 124.3 0.5 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EMT51923.1 - 1e-21 78.0 1.6 1.3e-21 77.7 1.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EMT51923.1 - 2.4e-15 56.9 0.1 3.5e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT51923.1 - 2e-11 44.4 4.4 2.9e-11 43.9 4.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein MitoNEET_N PF10660.9 EMT51923.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus ABC_tran PF00005.27 EMT51924.1 - 2.7e-36 125.1 0.0 5.1e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT51924.1 - 6.4e-11 42.6 0.0 6.6e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 EMT51924.1 - 1.2e-10 41.4 0.2 3.4e-10 39.9 0.0 2.0 2 0 0 2 2 1 1 TOBE domain SMC_N PF02463.19 EMT51924.1 - 7.3e-07 28.8 0.1 1.1e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 EMT51924.1 - 4.4e-05 23.9 0.2 0.00076 19.9 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EMT51924.1 - 9.3e-05 22.4 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EMT51924.1 - 0.00024 21.5 0.2 0.00063 20.2 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EMT51924.1 - 0.00094 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_ATPase PF09818.9 EMT51924.1 - 0.0013 17.6 2.2 0.025 13.4 0.2 3.2 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 EMT51924.1 - 0.0022 18.3 0.8 0.014 15.6 0.8 2.1 1 1 0 1 1 1 1 AAA domain TOBE_3 PF12857.7 EMT51924.1 - 0.0027 17.6 0.8 0.0056 16.6 0.1 2.0 2 0 0 2 2 1 1 TOBE-like domain AAA_28 PF13521.6 EMT51924.1 - 0.0036 17.6 0.2 0.0077 16.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT51924.1 - 0.0054 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EMT51924.1 - 0.0058 17.2 0.1 0.021 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EMT51924.1 - 0.008 16.2 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TOBE PF03459.17 EMT51924.1 - 0.0097 16.2 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 1 TOBE domain AAA_33 PF13671.6 EMT51924.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EMT51924.1 - 0.012 16.2 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EMT51924.1 - 0.017 14.8 0.2 0.06 13.1 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 EMT51924.1 - 0.023 14.3 0.1 0.67 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMT51924.1 - 0.031 14.0 0.1 0.29 10.8 0.0 2.1 2 1 1 3 3 3 0 AAA domain NACHT PF05729.12 EMT51924.1 - 0.034 14.1 0.2 0.13 12.2 0.1 2.0 3 0 0 3 3 2 0 NACHT domain Mg_chelatase PF01078.21 EMT51924.1 - 0.043 13.2 0.1 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 EMT51924.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase PhoH PF02562.16 EMT51924.1 - 0.05 13.1 0.1 0.4 10.1 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 EMT51924.1 - 0.069 13.5 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EMT51924.1 - 0.12 12.3 0.8 6.1 6.7 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_15 PF13175.6 EMT51924.1 - 0.13 11.9 0.0 0.78 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 EMT51924.1 - 0.14 11.8 0.1 8.3 6.0 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATPase PF06745.13 EMT51924.1 - 0.15 11.4 0.1 2.6 7.3 0.1 2.1 2 0 0 2 2 2 0 KaiC BPD_transp_1 PF00528.22 EMT51925.1 - 2.8e-20 72.9 39.7 2.3e-12 47.0 16.6 3.5 2 2 2 4 4 4 2 Binding-protein-dependent transport system inner membrane component DUF2852 PF11014.8 EMT51925.1 - 0.45 10.7 3.4 1.5 9.0 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Renin_r PF07850.14 EMT51925.1 - 0.55 10.9 2.1 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 Renin receptor-like protein HAD_2 PF13419.6 EMT51926.1 - 5.5e-12 46.1 0.0 8.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMT51926.1 - 1.4e-09 38.5 0.8 1.5e-08 35.2 0.1 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMT51926.1 - 1.2e-05 25.2 0.1 3.1e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 EMT51926.1 - 0.00042 20.8 0.1 0.0017 18.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NTPase_1 PF03266.15 EMT51926.1 - 0.12 12.3 0.1 0.81 9.6 0.0 2.1 2 0 0 2 2 2 0 NTPase DUF3394 PF11874.8 EMT51926.1 - 0.16 11.7 0.0 0.33 10.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) Aminotran_5 PF00266.19 EMT51927.1 - 8.8e-25 87.4 0.0 1.1e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EMT51927.1 - 1.7e-05 23.5 0.0 2.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DeoRC PF00455.22 EMT51928.1 - 1e-44 152.3 0.5 1.5e-44 151.8 0.5 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EMT51928.1 - 7.8e-15 54.4 1.1 1.4e-14 53.5 0.5 1.8 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain FaeA PF04703.12 EMT51928.1 - 1.6e-06 28.4 0.1 3.5e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 FaeA-like protein HTH_11 PF08279.12 EMT51928.1 - 1.6e-05 24.8 0.7 3.4e-05 23.7 0.7 1.6 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 EMT51928.1 - 0.0012 18.5 0.5 0.0025 17.4 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Helicase_RecD PF05127.14 EMT51928.1 - 0.013 15.4 0.5 0.064 13.1 0.1 2.0 2 0 0 2 2 2 0 Helicase HTH_24 PF13412.6 EMT51928.1 - 0.023 14.3 0.7 0.039 13.5 0.7 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 EMT51928.1 - 0.024 14.6 0.1 0.051 13.6 0.1 1.7 1 1 0 1 1 1 0 Winged helix-turn helix TFIIE_alpha PF02002.17 EMT51928.1 - 0.029 14.2 0.5 0.065 13.1 0.5 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit Fe_dep_repress PF01325.19 EMT51928.1 - 0.052 13.8 0.2 0.15 12.3 0.2 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_5 PF01022.20 EMT51928.1 - 0.065 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 EMT51928.1 - 0.11 12.4 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 MarR family Glyoxalase PF00903.25 EMT51929.1 - 8.7e-10 38.9 0.0 8.3e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EMT51929.1 - 0.00062 19.7 0.0 0.0021 18.0 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EMT51929.1 - 0.0019 18.4 0.0 0.0069 16.5 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EMT51929.1 - 0.032 15.0 0.0 0.054 14.3 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EMT51929.1 - 0.035 14.4 0.0 0.12 12.7 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3352 PF11832.8 EMT51929.1 - 0.19 10.3 0.0 0.24 10.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) NUDIX PF00293.28 EMT51930.1 - 5.5e-16 58.8 0.0 8.8e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NMO PF03060.15 EMT51931.1 - 1.2e-93 314.1 4.2 1.4e-93 313.9 4.2 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EMT51931.1 - 3.1e-09 36.3 1.0 0.00031 19.9 0.6 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 EMT51931.1 - 1.1e-05 24.9 1.2 4.4e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EMT51931.1 - 1.8e-05 23.9 2.7 6.2e-05 22.2 2.5 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EMT51931.1 - 0.004 16.6 0.1 0.0084 15.6 0.1 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein Glu_synthase PF01645.17 EMT51931.1 - 0.0042 16.3 4.8 0.016 14.4 0.3 2.5 3 0 0 3 3 3 1 Conserved region in glutamate synthase DUF561 PF04481.12 EMT51931.1 - 0.18 11.0 0.2 0.43 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF561) SBP_bac_1 PF01547.25 EMT51933.1 - 5e-36 125.3 6.4 6.6e-36 124.8 6.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EMT51933.1 - 9.8e-33 114.2 0.7 1.4e-32 113.7 0.7 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Propeptide_C1 PF08127.13 EMT51933.1 - 0.15 11.9 0.5 0.85 9.6 0.4 2.2 2 0 0 2 2 2 0 Peptidase family C1 propeptide BPD_transp_1 PF00528.22 EMT51934.1 - 1.1e-18 67.7 21.5 1.1e-18 67.7 21.5 2.6 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EMT51935.1 - 9.6e-19 67.8 20.9 9.6e-19 67.8 20.9 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component His_kinase PF06580.13 EMT51936.1 - 3.4e-24 85.0 3.5 2e-23 82.5 2.4 2.3 2 0 0 2 2 2 1 Histidine kinase dCache_1 PF02743.18 EMT51936.1 - 4.8e-21 75.7 0.1 8.4e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Cache domain HAMP PF00672.25 EMT51936.1 - 5.4e-10 39.5 0.1 1.2e-09 38.4 0.1 1.6 1 0 0 1 1 1 1 HAMP domain HATPase_c PF02518.26 EMT51936.1 - 2.8e-08 34.2 0.0 1.7e-07 31.8 0.0 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMT51936.1 - 0.0062 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4798 PF16055.5 EMT51936.1 - 0.014 15.7 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) HATPase_c_2 PF13581.6 EMT51936.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF1993 PF09351.10 EMT51936.1 - 0.061 13.5 0.2 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Response_reg PF00072.24 EMT51937.1 - 1.4e-27 96.1 0.6 8e-27 93.6 0.2 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HTH_18 PF12833.7 EMT51937.1 - 4.2e-22 78.2 0.7 1.3e-21 76.7 0.7 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EMT51937.1 - 2.6e-21 75.2 0.2 6.4e-11 42.1 0.0 2.8 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 EMT51937.1 - 0.011 15.5 0.1 1.2 9.0 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain DUF3323 PF11796.8 EMT51937.1 - 0.088 12.7 0.7 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Glyco_hydro_3 PF00933.21 EMT51938.1 - 1.9e-105 352.8 0.0 2.6e-105 352.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EMT51938.1 - 3.4e-05 23.9 0.0 0.00016 21.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.25 EMT51939.1 - 1.2e-13 51.3 0.0 1.6e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT51939.1 - 1.5e-07 31.4 0.0 2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT51939.1 - 7.9e-07 29.4 0.0 1.1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT51939.1 - 0.0001 22.5 0.0 0.00012 22.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT51939.1 - 0.00046 20.1 0.1 0.00061 19.7 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Amidohydro_1 PF01979.20 EMT51940.1 - 9.8e-28 97.4 1.8 1.2e-27 97.1 1.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMT51940.1 - 3.8e-14 53.0 1.4 2.6e-08 33.8 0.0 2.9 2 1 1 3 3 3 2 Amidohydrolase family DctA-YdbH PF11739.8 EMT51940.1 - 0.022 14.5 0.1 0.034 13.9 0.1 1.2 1 0 0 1 1 1 0 Dicarboxylate transport Xan_ur_permease PF00860.20 EMT51941.1 - 6.3e-57 193.0 36.8 9.2e-57 192.5 36.8 1.2 1 0 0 1 1 1 1 Permease family DUF2754 PF10953.8 EMT51941.1 - 0.026 14.8 0.3 0.026 14.8 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2754) IU_nuc_hydro PF01156.19 EMT51942.1 - 3.2e-81 273.2 0.8 3.9e-81 273.0 0.8 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase BPD_transp_2 PF02653.16 EMT51943.1 - 1.3e-36 126.2 35.7 1.5e-36 125.9 35.7 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component FecCD PF01032.18 EMT51943.1 - 1.5e-05 24.2 10.6 1.5e-05 24.2 10.6 2.5 1 1 1 2 2 2 1 FecCD transport family TRIQK PF15168.6 EMT51943.1 - 0.52 10.2 2.2 26 4.8 0.1 2.5 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family BPD_transp_2 PF02653.16 EMT51944.1 - 9.2e-44 149.6 21.9 9.2e-44 149.6 21.9 2.0 1 1 1 2 2 2 2 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 EMT51945.1 - 5.1e-50 169.5 0.5 2.1e-30 106.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMT51945.1 - 5.4e-09 36.3 0.3 0.00063 19.6 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EMT51945.1 - 0.00041 20.2 1.1 0.054 13.2 0.1 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EMT51945.1 - 0.00067 19.3 0.5 0.0027 17.4 0.1 2.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain SMC_N PF02463.19 EMT51945.1 - 0.00075 19.0 0.5 0.01 15.3 0.5 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMT51945.1 - 0.001 19.0 0.8 0.06 13.3 0.0 2.9 2 1 1 3 3 3 1 RsgA GTPase AAA_27 PF13514.6 EMT51945.1 - 0.002 17.7 0.1 0.0055 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMT51945.1 - 0.0031 17.8 0.1 0.44 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EMT51945.1 - 0.0047 17.0 0.1 33 4.5 0.0 3.5 2 1 0 3 3 3 0 AAA domain TrkA_C PF02080.21 EMT51945.1 - 0.0053 16.6 0.2 12 5.8 0.0 3.9 4 0 0 4 4 4 1 TrkA-C domain AAA_10 PF12846.7 EMT51945.1 - 0.0069 15.3 0.2 0.016 14.2 0.2 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_23 PF13476.6 EMT51945.1 - 0.013 16.0 2.3 0.015 15.8 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 EMT51945.1 - 0.025 14.3 0.5 0.66 9.7 0.1 2.8 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 EMT51945.1 - 0.057 12.6 0.1 0.17 11.0 0.1 1.8 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 EMT51945.1 - 0.12 12.4 0.1 0.61 10.2 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Bmp PF02608.14 EMT51946.1 - 2.2e-56 191.1 5.3 2.6e-56 190.8 5.3 1.1 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Peripla_BP_4 PF13407.6 EMT51946.1 - 1.6e-09 37.7 1.5 2.4e-09 37.2 1.5 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 EMT51946.1 - 0.00081 18.9 0.0 0.0026 17.2 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family PfkB PF00294.24 EMT51947.1 - 8.6e-64 215.7 0.6 9.7e-64 215.5 0.6 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EMT51947.1 - 6.4e-07 29.0 0.1 1.2e-06 28.1 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Peripla_BP_1 PF00532.21 EMT51948.1 - 3.9e-35 121.6 0.0 5.3e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 EMT51948.1 - 1.2e-29 103.8 0.0 2.2e-26 93.2 0.0 2.5 2 1 1 3 3 3 2 Periplasmic binding protein-like domain Peripla_BP_4 PF13407.6 EMT51948.1 - 3.2e-27 95.7 0.0 8.1e-27 94.4 0.0 1.6 2 0 0 2 2 2 1 Periplasmic binding protein domain LacI PF00356.21 EMT51948.1 - 6.2e-20 70.7 1.2 6.2e-20 70.7 1.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family DUF3853 PF12964.7 EMT51948.1 - 0.0015 18.7 0.1 0.04 14.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3853) CbiJ PF02571.14 EMT51948.1 - 0.0042 16.6 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK HTH_Tnp_ISL3 PF13542.6 EMT51948.1 - 0.0063 15.9 0.3 0.047 13.1 0.3 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EMT51948.1 - 0.012 15.4 0.0 0.048 13.5 0.0 2.1 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 EMT51948.1 - 0.024 14.4 0.1 0.063 13.1 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 EMT51948.1 - 0.024 14.7 0.0 0.068 13.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix TnsD PF15978.5 EMT51948.1 - 0.029 13.4 0.1 0.038 13.0 0.1 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_31 PF13560.6 EMT51948.1 - 0.03 14.7 0.1 0.093 13.1 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 EMT51948.1 - 0.036 14.1 0.3 0.17 12.0 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Trp_repressor PF01371.19 EMT51948.1 - 0.036 14.2 0.2 0.071 13.3 0.2 1.5 1 0 0 1 1 1 0 Trp repressor protein HTH_17 PF12728.7 EMT51948.1 - 0.042 14.0 0.1 0.19 12.0 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain MerR PF00376.23 EMT51948.1 - 0.059 13.1 0.2 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 MerR family regulatory protein PucR PF07905.11 EMT51948.1 - 0.069 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family SpoIIID PF12116.8 EMT51948.1 - 0.23 11.6 0.9 0.4 10.8 0.3 1.7 2 0 0 2 2 2 0 Stage III sporulation protein D PfkB PF00294.24 EMT51949.1 - 1.5e-72 244.4 1.1 1.7e-72 244.3 1.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EMT51949.1 - 2.3e-12 46.8 0.2 3.3e-12 46.3 0.2 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Rod-binding PF10135.9 EMT51949.1 - 0.038 14.6 0.3 0.27 11.9 0.0 2.2 2 0 0 2 2 2 0 Rod binding protein Vir_act_alpha_C PF10400.9 EMT51950.1 - 1.7e-17 63.8 0.6 1.7e-17 63.8 0.6 1.6 2 1 0 2 2 2 1 Virulence activator alpha C-term PadR PF03551.14 EMT51950.1 - 3e-16 59.2 0.0 5.1e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 EMT51950.1 - 8.1e-05 22.7 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain RTP PF02334.16 EMT51950.1 - 0.03 15.0 0.0 0.12 13.1 0.0 1.8 2 0 0 2 2 2 0 Replication terminator protein Mrr_N PF14338.6 EMT51950.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Mrr N-terminal domain HTH_27 PF13463.6 EMT51950.1 - 0.085 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Multi_Drug_Res PF00893.19 EMT51951.1 - 4.8e-32 110.5 10.6 6.9e-32 110.0 10.6 1.2 1 0 0 1 1 1 1 Small Multidrug Resistance protein FPN1 PF06963.12 EMT51951.1 - 0.076 11.6 3.7 0.051 12.1 1.6 1.5 1 1 1 2 2 2 0 Ferroportin1 (FPN1) DUF3754 PF12576.8 EMT51951.1 - 0.1 12.6 4.1 0.1 12.6 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3754) ABC_tran PF00005.27 EMT51952.1 - 1.3e-38 132.6 0.0 2.9e-38 131.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 EMT51952.1 - 3.5e-12 46.3 0.0 7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 EMT51952.1 - 8.4e-08 32.4 0.0 0.0093 15.8 0.0 2.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMT51952.1 - 3e-05 24.5 0.0 5.5e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EMT51952.1 - 5.5e-05 22.7 0.7 0.0028 17.1 0.5 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 EMT51952.1 - 0.0011 18.4 0.0 0.02 14.3 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 EMT51952.1 - 0.0014 19.1 0.3 0.013 15.9 0.3 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMT51952.1 - 0.0015 18.8 0.5 0.0044 17.3 0.5 1.9 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EMT51952.1 - 0.0042 17.0 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EMT51952.1 - 0.0053 16.7 0.1 0.016 15.2 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EMT51952.1 - 0.034 13.7 0.2 0.27 10.8 0.1 2.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EMT51952.1 - 0.039 14.3 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.12 EMT51952.1 - 0.043 13.7 0.4 0.093 12.6 0.1 1.7 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 EMT51952.1 - 0.053 13.4 0.0 0.081 12.8 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EMT51952.1 - 0.054 13.5 0.0 0.39 10.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EMT51952.1 - 0.056 12.2 0.1 2.8 6.6 0.0 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 EMT51952.1 - 0.06 12.5 0.3 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 EMT51952.1 - 0.072 12.5 0.2 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 EMT51952.1 - 0.081 13.2 0.8 0.29 11.3 0.1 2.2 3 0 0 3 3 3 0 AAA domain FeoB_N PF02421.18 EMT51952.1 - 0.083 12.4 0.1 9.4 5.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 EMT51952.1 - 0.097 11.8 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 EMT51952.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT51952.1 - 0.57 10.6 0.1 0.57 10.6 0.1 2.2 2 1 0 2 2 1 0 AAA domain BPD_transp_1 PF00528.22 EMT51953.1 - 3.2e-13 49.8 29.9 4.2e-12 46.2 29.9 2.2 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EMT51954.1 - 5.7e-20 71.8 11.6 5.7e-20 71.8 11.6 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.21 EMT51954.1 - 0.52 10.8 18.0 0.64 10.5 0.4 3.2 3 1 0 3 3 3 0 FtsX-like permease family SBP_bac_8 PF13416.6 EMT51955.1 - 1.7e-40 139.6 7.0 2.2e-40 139.2 7.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EMT51955.1 - 2.4e-37 128.7 1.4 3.4e-37 128.2 1.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT51955.1 - 7.5e-18 65.5 13.2 9.5e-18 65.2 10.5 2.2 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EMT51955.1 - 1.6e-13 51.0 0.0 2.7e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein BsuBI_PstI_RE PF06616.11 EMT51955.1 - 0.049 12.9 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease domain Abhydrolase_1 PF00561.20 EMT51956.1 - 1.1e-24 87.5 0.0 2.3e-23 83.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMT51956.1 - 4.6e-22 79.7 0.1 5.8e-22 79.4 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMT51956.1 - 6.1e-11 42.0 0.1 7.8e-10 38.4 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EMT51956.1 - 0.00053 19.6 0.0 0.00073 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Esterase PF00756.20 EMT51956.1 - 0.0021 17.8 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 EMT51956.1 - 0.0089 14.8 0.0 0.013 14.2 0.0 1.4 1 1 0 1 1 1 1 Ndr family PGAP1 PF07819.13 EMT51956.1 - 0.12 12.1 0.0 0.52 10.0 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein LysR_substrate PF03466.20 EMT51957.1 - 1.4e-43 148.7 0.0 1.9e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT51957.1 - 3.2e-19 68.6 0.0 6.7e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF2089 PF09862.9 EMT51957.1 - 0.00094 19.2 0.0 0.0029 17.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2089) HTH_30 PF13556.6 EMT51957.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 EMT51957.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Aminotran_4 PF01063.19 EMT51958.1 - 5.8e-48 163.7 0.0 6.9e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV PGM_PMM_I PF02878.16 EMT51958.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Peptidase_M19 PF01244.21 EMT51959.1 - 2.4e-101 339.1 0.0 2.9e-101 338.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Peptidase_S58 PF03576.14 EMT51960.1 - 2.5e-109 365.4 1.3 2.9e-109 365.2 1.3 1.0 1 0 0 1 1 1 1 Peptidase family S58 Beta-lactamase PF00144.24 EMT51961.1 - 1.1e-68 232.0 0.0 1.4e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EMT51961.1 - 0.01 16.3 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Peptidase_S11 PF00768.20 EMT51961.1 - 0.014 14.9 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 EMT51961.1 - 0.031 13.9 0.0 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase enzyme family WYL PF13280.6 EMT51962.1 - 0.0082 16.2 0.8 0.014 15.5 0.8 1.3 1 1 0 1 1 1 1 WYL domain Glyoxalase PF00903.25 EMT51963.1 - 2.9e-14 53.4 0.0 3.3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EMT51963.1 - 2.7e-06 28.1 0.0 3.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EMT51963.1 - 2.2e-05 24.3 0.0 6.9e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EMT51963.1 - 0.0052 17.0 0.2 0.31 11.3 0.2 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EMT51963.1 - 0.12 12.4 0.0 3.6 7.7 0.0 2.0 1 1 0 2 2 2 0 Glyoxalase-like domain Fungus-induced PF10917.8 EMT51964.1 - 0.31 11.4 0.2 0.31 11.4 0.2 2.3 2 0 0 2 2 2 0 Fungus-induced protein RsgA_GTPase PF03193.16 EMT51965.1 - 1.1e-51 175.0 0.0 1.6e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EMT51965.1 - 4.1e-08 33.3 0.0 9.2e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMT51965.1 - 2.4e-06 27.2 0.2 0.017 14.7 0.1 2.4 2 1 0 2 2 2 2 Ferrous iron transport protein B ABC_tran PF00005.27 EMT51965.1 - 1.6e-05 25.4 0.0 3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 EMT51965.1 - 0.00056 20.2 1.2 0.001 19.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 EMT51965.1 - 0.0037 17.0 0.6 0.53 10.0 0.1 3.2 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 EMT51965.1 - 0.0041 16.1 0.1 0.0077 15.2 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EMT51965.1 - 0.0077 16.3 0.6 0.041 14.0 0.3 2.3 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 EMT51965.1 - 0.011 16.2 0.2 0.03 14.7 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 EMT51965.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EMT51965.1 - 0.018 14.8 0.2 0.042 13.6 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EMT51965.1 - 0.028 15.0 0.0 0.087 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMT51965.1 - 0.034 13.9 0.0 0.076 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 EMT51965.1 - 0.035 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 EMT51965.1 - 0.044 13.1 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 Septin cobW PF02492.19 EMT51965.1 - 0.063 12.9 0.2 6.8 6.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EMT51965.1 - 0.1 12.9 0.4 0.24 11.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 EMT51965.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Pribosyltran PF00156.27 EMT51966.1 - 6.4e-12 45.3 0.9 1.7e-11 43.9 0.9 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EMT51966.1 - 0.08 12.4 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase Xan_ur_permease PF00860.20 EMT51967.1 - 8.4e-113 377.0 45.2 1.2e-112 376.5 45.2 1.2 1 0 0 1 1 1 1 Permease family MCPsignal PF00015.21 EMT51968.1 - 9.9e-41 139.4 31.3 1.2e-38 132.7 21.7 3.1 1 1 2 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Protoglobin PF11563.8 EMT51968.1 - 1.5e-40 138.7 0.0 4.8e-40 137.0 0.0 1.9 1 0 0 1 1 1 1 Protoglobin CZB PF13682.6 EMT51968.1 - 4.8e-14 52.5 4.0 1.1e-13 51.4 4.0 1.7 1 0 0 1 1 1 1 Chemoreceptor zinc-binding domain WXG100 PF06013.12 EMT51968.1 - 0.04 14.1 0.6 0.04 14.1 0.6 4.9 3 2 2 6 6 6 0 Proteins of 100 residues with WXG Transcrip_act PF04949.13 EMT51968.1 - 0.053 13.4 4.2 3.3 7.6 0.0 3.8 1 1 2 3 3 3 0 Transcriptional activator RepL PF05732.11 EMT51968.1 - 0.054 12.9 2.3 0.53 9.7 0.4 2.4 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) DUF1664 PF07889.12 EMT51968.1 - 0.068 13.2 17.2 0.62 10.1 0.7 4.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 EMT51968.1 - 0.07 13.5 13.6 5.4 7.4 4.5 4.6 3 1 1 5 5 5 0 Syntaxin-like protein Med9 PF07544.13 EMT51968.1 - 0.14 12.3 3.8 1.1 9.4 0.2 3.5 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.11 EMT51968.1 - 0.64 10.3 21.4 0.53 10.6 3.3 4.8 3 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 EMT51968.1 - 0.7 10.1 14.0 0.44 10.7 1.5 3.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Alanine_zipper PF11839.8 EMT51968.1 - 0.86 10.0 17.3 2.8 8.4 0.5 4.0 4 0 0 4 4 3 0 Alanine-zipper, major outer membrane lipoprotein DUF2203 PF09969.9 EMT51968.1 - 1.8 9.3 15.6 0.81 10.4 0.5 4.0 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) Sec34 PF04136.15 EMT51968.1 - 2 8.3 10.1 2.6 7.9 0.7 3.8 2 2 1 3 3 3 0 Sec34-like family AIP3 PF03915.13 EMT51968.1 - 3.4 6.6 18.1 25 3.8 17.8 2.3 2 1 0 2 2 2 0 Actin interacting protein 3 FIVAR PF07554.13 EMT51968.1 - 4.5 8.1 8.9 0.69 10.7 3.5 2.5 2 0 0 2 2 2 0 FIVAR domain Laminin_II PF06009.12 EMT51968.1 - 6.8 6.7 22.0 2.8 8.0 1.8 4.3 2 2 2 4 4 4 0 Laminin Domain II RAC_head PF16717.5 EMT51968.1 - 7.5 7.6 6.8 1.4 10.0 0.5 2.9 1 1 2 3 3 3 0 Ribosome-associated complex head domain Glyoxalase PF00903.25 EMT51969.1 - 2.8e-16 59.8 0.0 4.3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EMT51969.1 - 1.2e-08 35.7 0.0 1.5e-08 35.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EMT51969.1 - 6.3e-06 26.1 0.0 8.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EMT51969.1 - 0.025 14.8 0.0 0.43 10.9 0.0 2.1 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 EMT51969.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 CppA N-terminal CP12 PF02672.15 EMT51970.1 - 1.4 9.7 7.2 2.1 9.2 7.2 1.3 1 0 0 1 1 1 0 CP12 domain Endopep_inhib PF16800.5 EMT51971.1 - 5.2e-05 23.2 0.0 6.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 IseA DL-endopeptidase inhibitor HipA_C PF07804.12 EMT51972.1 - 0.0049 16.6 0.2 0.09 12.5 0.2 2.3 1 1 0 1 1 1 1 HipA-like C-terminal domain PI3_PI4_kinase PF00454.27 EMT51972.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase CotH PF08757.11 EMT51972.1 - 0.024 14.2 0.6 0.042 13.4 0.6 1.4 1 1 0 1 1 1 0 CotH kinase protein Gate PF07670.14 EMT51973.1 - 9.1e-22 77.5 18.5 2.3e-15 56.8 3.4 3.2 3 1 0 3 3 3 2 Nucleoside recognition FeoB_C PF07664.12 EMT51973.1 - 5.3e-13 48.4 2.0 1.1e-12 47.4 0.5 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B C terminus FeoB_N PF02421.18 EMT51974.1 - 6.2e-60 201.3 0.3 7.6e-60 201.0 0.3 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EMT51974.1 - 2.3e-19 69.5 0.0 3.5e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_Cyto PF17910.1 EMT51974.1 - 3.1e-10 40.4 0.0 6.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 FeoB cytosolic helical domain GTP_EFTU PF00009.27 EMT51974.1 - 7.8e-08 32.1 0.2 6.6e-06 25.8 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EMT51974.1 - 1.2e-05 25.4 0.2 0.046 13.8 0.1 2.2 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.10 EMT51974.1 - 5.3e-05 22.7 0.0 7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EMT51974.1 - 5.6e-05 23.1 0.3 0.052 13.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EMT51974.1 - 0.00022 20.6 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 EMT51974.1 - 0.0065 17.0 0.2 0.0093 16.5 0.2 1.5 1 1 0 1 1 1 1 ABC transporter PduV-EutP PF10662.9 EMT51974.1 - 0.043 13.5 0.2 0.15 11.8 0.2 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 EMT51974.1 - 0.085 11.8 0.3 4 6.3 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 EMT51974.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 EMT51974.1 - 0.12 12.8 0.1 0.33 11.3 0.1 1.8 1 1 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 EMT51974.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoA PF04023.14 EMT51975.1 - 4.2e-16 59.0 0.1 4.6e-16 58.8 0.1 1.0 1 0 0 1 1 1 1 FeoA domain HTH_5 PF01022.20 EMT51976.1 - 9e-18 63.9 0.2 1.6e-17 63.1 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EMT51976.1 - 5.5e-08 32.7 0.1 9.3e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EMT51976.1 - 0.0087 15.8 0.7 0.1 12.4 0.0 2.2 1 1 1 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 EMT51976.1 - 0.054 13.4 0.2 0.11 12.4 0.2 1.5 1 1 0 1 1 1 0 MarR family HxlR PF01638.17 EMT51976.1 - 0.062 13.2 0.1 0.086 12.7 0.1 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_IclR PF09339.10 EMT51976.1 - 0.084 12.7 1.0 0.23 11.3 0.1 2.1 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_1 PF00126.27 EMT51976.1 - 0.088 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family E1-E2_ATPase PF00122.20 EMT51977.1 - 1.1e-56 191.2 0.9 1.1e-56 191.2 0.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMT51977.1 - 2e-47 162.2 1.0 2e-47 162.2 1.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EMT51977.1 - 5.6e-12 45.9 0.4 1.3e-11 44.8 0.4 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Peptidase_M17_N PF02789.17 EMT51977.1 - 0.0024 17.7 0.4 0.0081 16.0 0.4 1.9 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Hydrolase_3 PF08282.12 EMT51977.1 - 0.0056 16.4 2.6 0.018 14.8 1.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DJ-1_PfpI PF01965.24 EMT51978.1 - 6.5e-47 159.4 0.0 7.2e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EMT51978.1 - 0.16 11.6 0.0 1.5 8.5 0.0 2.0 1 1 0 1 1 1 0 ThiJ/PfpI family-like DUF3082 PF11282.8 EMT51979.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) Spore_GerAC PF05504.11 EMT51980.1 - 1.2e-31 110.2 0.6 2e-31 109.4 0.6 1.4 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal MukF_M PF17192.4 EMT51980.1 - 0.097 12.4 0.2 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 MukF middle domain Spore_permease PF03845.13 EMT51981.1 - 1.5e-70 237.6 31.0 1.9e-70 237.2 31.0 1.1 1 0 0 1 1 1 1 Spore germination protein Proton_antipo_N PF00662.20 EMT51981.1 - 0.044 13.9 0.1 0.044 13.9 0.1 3.3 4 0 0 4 4 4 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF5472 PF17566.2 EMT51981.1 - 9 6.3 7.2 3.8 7.5 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5472) UL41A PF17591.2 EMT51981.1 - 9.8 6.4 7.2 9.2 6.5 0.3 3.4 2 1 2 4 4 4 0 Herpesvirus UL41A GerA PF03323.13 EMT51982.1 - 3.2e-185 616.1 0.6 3.7e-185 615.9 0.6 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein Dynamin_N PF00350.23 EMT51983.1 - 3.1e-25 89.2 0.1 1.5e-24 86.9 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EMT51983.1 - 3.8e-10 39.8 1.0 1.5e-09 37.9 0.0 2.6 2 2 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMT51983.1 - 3.9e-08 33.1 0.2 1.2e-07 31.5 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EMT51983.1 - 6.6e-06 25.7 3.9 0.0005 19.6 0.1 2.6 3 0 0 3 3 3 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EMT51983.1 - 0.00069 19.5 0.0 0.035 14.0 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase IIGP PF05049.13 EMT51983.1 - 0.0023 17.0 0.4 1.4 7.9 0.5 2.5 2 1 0 2 2 2 2 Interferon-inducible GTPase (IIGP) Septin PF00735.18 EMT51983.1 - 0.0044 16.3 0.1 0.013 14.8 0.0 1.8 2 0 0 2 2 2 1 Septin T4_Gp59_N PF08993.10 EMT51983.1 - 0.019 15.3 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase DUF5324 PF17258.2 EMT51983.1 - 0.02 14.6 0.7 6.1 6.5 0.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5324) NOG1 PF06858.14 EMT51983.1 - 0.023 14.5 1.5 0.26 11.1 0.1 2.7 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) DUF2357 PF09823.9 EMT51983.1 - 0.025 13.8 2.5 0.1 11.9 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2357) FtsK_SpoIIIE PF01580.18 EMT51983.1 - 0.073 12.4 2.4 0.25 10.7 0.1 2.6 2 1 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.27 EMT51983.1 - 0.29 11.6 1.5 5.4 7.5 0.0 3.1 2 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 EMT51984.1 - 3.4e-39 134.6 0.0 6.3e-39 133.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EMT51984.1 - 2.6e-08 33.9 0.0 2.7e-07 30.6 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMT51984.1 - 0.03 14.2 0.0 0.53 10.2 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Sec7_N PF12783.7 EMT51984.1 - 0.1 12.5 0.1 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RcpB PF16971.5 EMT51985.1 - 0.53 10.2 3.3 0.71 9.7 3.3 1.1 1 0 0 1 1 1 0 Rough colony protein B, tight adherence - tad - subunit SSF PF00474.17 EMT51987.1 - 2e-111 372.7 31.8 2e-111 372.7 31.8 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family SPATA24 PF15175.6 EMT51988.1 - 0.0035 17.3 0.5 0.0055 16.6 0.5 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 SMBP PF16785.5 EMT51988.1 - 0.035 14.3 2.2 0.084 13.1 2.2 1.6 1 1 0 1 1 1 0 Small metal-binding protein LPAM_1 PF08139.12 EMT51988.1 - 0.12 12.9 3.6 0.2 12.2 3.6 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Dynein_light PF01221.18 EMT51988.1 - 0.32 11.3 1.1 0.71 10.2 1.1 1.6 1 1 0 1 1 1 0 Dynein light chain type 1 CSD PF00313.22 EMT51989.1 - 1.5e-28 98.4 0.1 1.7e-28 98.3 0.1 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EMT51989.1 - 0.0036 17.0 0.1 0.0059 16.3 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain Thymidylat_synt PF00303.19 EMT51990.1 - 2.4e-124 413.8 0.0 2.7e-124 413.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DUF3630 PF12305.8 EMT51990.1 - 0.051 13.7 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) DHFR_1 PF00186.19 EMT51991.1 - 2.1e-59 199.9 0.0 2.3e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase DUF1122 PF06557.11 EMT51991.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) ATPgrasp_YheCD PF14398.6 EMT51992.1 - 3.1e-81 272.4 0.0 3.7e-81 272.2 0.0 1.0 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EMT51992.1 - 1.3e-06 27.9 0.0 0.0075 15.6 0.0 2.7 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 EMT51992.1 - 0.0019 17.6 0.0 0.0058 16.0 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain TTL PF03133.15 EMT51992.1 - 0.014 14.6 0.1 0.079 12.1 0.0 2.1 2 1 1 3 3 3 0 Tubulin-tyrosine ligase family Hydrolase_4 PF12146.8 EMT51993.1 - 1.4e-09 37.6 0.0 1e-06 28.2 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMT51993.1 - 1.9e-07 30.8 0.1 8.5e-07 28.7 0.1 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EMT51993.1 - 1.1e-05 25.5 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 EMT51993.1 - 0.00079 19.0 0.1 0.025 14.1 0.1 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 EMT51993.1 - 0.00095 17.8 0.0 0.22 10.0 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 EMT51993.1 - 0.00097 18.9 0.1 0.0042 16.8 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold ZNRF_3_ecto PF18212.1 EMT51993.1 - 0.0038 17.2 0.1 0.0078 16.2 0.1 1.5 1 0 0 1 1 1 1 ZNRF-3 Ectodomain BAAT_C PF08840.11 EMT51993.1 - 0.0041 17.1 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF676 PF05057.14 EMT51993.1 - 0.009 15.5 0.0 0.29 10.6 0.0 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 EMT51993.1 - 0.032 13.1 0.0 0.062 12.2 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 EMT51993.1 - 0.038 13.8 0.0 0.71 9.6 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EMT51993.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF1749 PF08538.10 EMT51993.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) HMGL-like PF00682.19 EMT51994.1 - 1.3e-47 162.6 0.0 3e-47 161.4 0.0 1.6 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 EMT51994.1 - 9.2e-30 103.3 0.0 1.7e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain SDF PF00375.18 EMT51995.1 - 1.2e-137 459.1 40.8 1.4e-137 458.9 40.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF1128 PF06569.11 EMT51996.1 - 2.3e-32 110.8 0.3 2.5e-32 110.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1128) DUF3861 PF12977.7 EMT51996.1 - 0.084 13.0 0.0 0.26 11.5 0.0 1.7 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) Peptidase_U32 PF01136.19 EMT51997.1 - 2e-108 361.0 0.1 5.6e-85 284.2 0.0 3.0 3 0 0 3 3 3 2 Peptidase family U32 DUF3656 PF12392.8 EMT51997.1 - 1.3e-24 86.9 0.0 2.9e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Collagenase Integrin_B_tail PF07965.12 EMT51997.1 - 0.61 10.6 2.2 4 8.0 0.3 2.3 2 0 0 2 2 2 0 Integrin beta tail domain HATPase_c PF02518.26 EMT51998.1 - 3.4e-07 30.7 0.0 4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SBD PF17882.1 EMT51998.1 - 0.0044 16.9 0.1 0.0059 16.4 0.1 1.2 1 0 0 1 1 1 1 OAA-family lectin sugar binding domain HATPase_c_3 PF13589.6 EMT51998.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TetR_N PF00440.23 EMT51999.1 - 2.1e-16 59.5 0.3 3.8e-16 58.6 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EMT51999.1 - 8.9e-07 29.2 0.0 1.6e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_4 PF08359.11 EMT51999.1 - 0.022 14.9 0.1 0.036 14.2 0.1 1.5 1 1 0 1 1 1 0 YsiA-like protein, C-terminal region TetR_C_10 PF16295.5 EMT51999.1 - 0.04 14.2 0.1 0.089 13.1 0.1 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Acetyltransf_1 PF00583.25 EMT52000.1 - 1.7e-12 47.6 0.0 2.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT52000.1 - 6.5e-09 35.8 0.0 8.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT52000.1 - 2e-08 34.5 0.1 3.2e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT52000.1 - 0.0039 17.3 0.0 0.12 12.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EMT52000.1 - 0.018 15.2 0.2 0.026 14.7 0.2 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT52000.1 - 0.052 13.5 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 EMT52000.1 - 0.074 13.2 0.1 0.47 10.6 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3959 PF13105.6 EMT52000.1 - 0.077 12.5 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Acetyltransf_CG PF14542.6 EMT52000.1 - 0.093 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EMT52000.1 - 0.13 12.9 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sigma70_r4_2 PF08281.12 EMT52001.1 - 1.6e-14 53.3 0.6 3.5e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT52001.1 - 5.3e-12 45.3 1.6 9.1e-12 44.6 1.6 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EMT52001.1 - 5.2e-09 35.5 0.2 1.2e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT52001.1 - 3.4e-05 23.8 0.3 0.011 15.6 0.0 2.3 2 0 0 2 2 2 2 ECF sigma factor HTH_16 PF12645.7 EMT52001.1 - 0.00049 20.1 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 EMT52001.1 - 0.0064 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EMT52001.1 - 0.021 14.3 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Phage_antitermQ PF06530.12 EMT52001.1 - 0.029 14.3 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 Phage antitermination protein Q HTH_23 PF13384.6 EMT52001.1 - 0.037 13.8 0.7 0.28 11.0 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain UPF0122 PF04297.14 EMT52001.1 - 0.037 14.3 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_24 PF13412.6 EMT52001.1 - 0.07 12.7 0.0 0.21 11.2 0.0 1.8 1 1 1 2 2 2 0 Winged helix-turn-helix DNA-binding GNAT_acetyltran PF12746.7 EMT52002.1 - 4.7e-54 183.5 0.0 5.9e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_1 PF00583.25 EMT52002.1 - 8.7e-06 26.0 0.6 2.3e-05 24.6 0.6 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EMT52002.1 - 0.0004 21.1 0.0 0.00058 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT52002.1 - 0.026 14.5 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein MCPsignal PF00015.21 EMT52003.1 - 1.2e-42 145.7 42.6 4.1e-40 137.4 24.6 3.6 1 1 3 4 4 4 4 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 EMT52003.1 - 1.2e-19 71.1 4.6 3.3e-19 69.7 0.0 3.0 2 1 2 4 4 4 1 Cache domain DUF948 PF06103.11 EMT52003.1 - 1.3e-06 28.6 16.3 0.0029 17.8 0.1 5.1 3 1 1 4 4 4 2 Bacterial protein of unknown function (DUF948) HAMP PF00672.25 EMT52003.1 - 1.2e-05 25.6 0.1 1.2e-05 25.6 0.1 4.7 6 0 0 6 6 5 1 HAMP domain DUF1664 PF07889.12 EMT52003.1 - 0.00017 21.6 13.7 0.21 11.6 0.0 4.4 2 2 2 4 4 4 2 Protein of unknown function (DUF1664) DUF1043 PF06295.12 EMT52003.1 - 0.0054 16.7 1.0 0.36 10.8 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1043) Mce4_CUP1 PF11887.8 EMT52003.1 - 0.028 13.9 4.1 0.052 13.0 0.8 2.6 2 1 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative Med30 PF11315.8 EMT52003.1 - 0.029 14.6 2.9 0.097 12.9 0.2 2.6 2 1 0 2 2 2 0 Mediator complex subunit 30 Prominin PF05478.11 EMT52003.1 - 0.059 11.3 5.7 0.73 7.7 0.2 2.5 1 1 0 2 2 2 0 Prominin Sec34 PF04136.15 EMT52003.1 - 0.1 12.5 2.9 9.1 6.1 0.0 4.0 2 2 2 5 5 5 0 Sec34-like family DUF3450 PF11932.8 EMT52003.1 - 0.47 9.7 24.7 0.3 10.4 4.7 4.8 3 3 2 5 5 5 0 Protein of unknown function (DUF3450) DASH_Dad1 PF08649.10 EMT52003.1 - 0.56 10.4 2.8 3.2 8.0 0.1 3.3 2 1 1 3 3 2 0 DASH complex subunit Dad1 Prefoldin_3 PF13758.6 EMT52003.1 - 1.3 9.2 4.0 11 6.1 0.1 3.6 3 1 1 4 4 4 0 Prefoldin subunit Fib_alpha PF08702.10 EMT52003.1 - 2.2 8.4 9.4 9.3 6.4 0.2 3.9 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 EMT52003.1 - 2.8 8.3 13.4 27 5.2 0.1 5.3 3 2 4 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Corona_S2 PF01601.16 EMT52003.1 - 3.5 6.0 11.7 0.084 11.3 1.3 2.3 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein COG2 PF06148.11 EMT52003.1 - 3.5 7.7 15.1 8.5 6.5 1.1 4.5 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 RelA_SpoT PF04607.17 EMT52004.1 - 1.3e-34 118.9 0.2 2.6e-34 118.0 0.2 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins DUF4364 PF14277.6 EMT52004.1 - 0.064 13.0 0.5 0.064 13.0 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Med9 PF07544.13 EMT52004.1 - 0.068 13.3 0.8 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.12 EMT52004.1 - 0.08 13.0 0.2 3.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2730 PF10805.8 EMT52004.1 - 0.11 12.6 0.6 4.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) HU-CCDC81_bac_2 PF18175.1 EMT52004.1 - 0.15 11.9 3.1 4.6 7.2 0.1 3.0 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 FlaC_arch PF05377.11 EMT52004.1 - 0.18 12.2 1.9 12 6.4 0.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Peptidase_M20 PF01546.28 EMT52005.1 - 8.3e-31 107.3 0.1 1.3e-30 106.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT52005.1 - 1.1e-06 28.5 0.0 0.0005 20.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT52005.1 - 0.00044 20.0 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 DEAD PF00270.29 EMT52006.1 - 1.3e-52 178.1 0.7 1.3e-52 178.1 0.7 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMT52006.1 - 3.5e-35 120.7 1.3 4.8e-32 110.6 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EMT52006.1 - 1.5e-06 28.3 1.5 3.1e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EMT52006.1 - 0.039 13.8 2.4 0.34 10.8 0.0 3.0 2 1 0 3 3 3 0 Helicase AAA_22 PF13401.6 EMT52006.1 - 0.093 13.0 1.0 0.46 10.7 0.8 2.4 1 1 0 1 1 1 0 AAA domain DUF573 PF04504.14 EMT52006.1 - 0.42 11.3 4.7 1.6 9.4 3.1 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF573 AAA_11 PF13086.6 EMT52006.1 - 4.4 7.0 7.7 32 4.2 4.0 2.8 2 1 1 3 3 3 0 AAA domain Beta-lactamase PF00144.24 EMT52008.1 - 9.5e-64 215.7 2.7 1.2e-63 215.3 2.7 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EMT52008.1 - 0.035 13.7 0.0 0.083 12.5 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase enzyme family RCR PF12273.8 EMT52008.1 - 0.34 11.6 3.7 0.92 10.2 3.7 1.8 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF3810 PF12725.7 EMT52008.1 - 0.41 9.9 3.7 0.91 8.8 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Glucos_trans_II PF14264.6 EMT52008.1 - 0.97 8.7 13.3 0.012 15.0 5.5 1.6 2 0 0 2 2 2 0 Glucosyl transferase GtrII YfhO PF09586.10 EMT52008.1 - 3.2 5.8 6.2 6.7 4.8 6.2 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1129 PF06570.11 EMT52008.1 - 3.5 7.1 6.1 6.1 6.3 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2070 PF09843.9 EMT52008.1 - 4.4 5.5 7.9 6.5 4.9 7.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HTH_24 PF13412.6 EMT52009.1 - 0.0012 18.3 0.1 0.0074 15.8 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding DZR PF12773.7 EMT52009.1 - 0.0038 17.2 1.3 0.0056 16.7 1.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF2116 PF09889.9 EMT52009.1 - 0.01 15.8 0.5 0.014 15.3 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) HTH_7 PF02796.15 EMT52009.1 - 0.094 12.8 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Methyltr_RsmB-F PF01189.17 EMT52010.1 - 7.2e-52 175.9 0.0 9.4e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EMT52010.1 - 2.2e-34 117.8 0.0 5.3e-34 116.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltranf_PUA PF13636.6 EMT52010.1 - 6.2e-22 77.3 0.6 1.1e-21 76.5 0.6 1.5 1 0 0 1 1 1 1 RNA-binding PUA-like domain of methyltransferase RsmF RsmF_methylt_CI PF17126.5 EMT52010.1 - 9.8e-21 73.6 0.0 2e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 RsmF rRNA methyltransferase first C-terminal domain FtsJ PF01728.19 EMT52010.1 - 1.2e-06 28.8 0.0 3.8e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.16 EMT52010.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.17 EMT52010.1 - 0.022 14.2 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_31 PF13847.6 EMT52010.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EMT52010.1 - 0.096 13.4 0.0 0.48 11.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EMT52010.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CcmH PF03918.14 EMT52011.1 - 0.086 12.1 0.6 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF4010 PF13194.6 EMT52011.1 - 0.097 12.3 3.3 0.17 11.5 3.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4010) DUF3278 PF11683.8 EMT52011.1 - 0.29 11.2 3.3 0.18 11.9 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) DUF2304 PF10066.9 EMT52011.1 - 2.8 8.2 11.5 0.31 11.3 1.5 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) MCPsignal PF00015.21 EMT52012.1 - 6.4e-43 146.5 32.6 6.4e-43 146.5 25.9 2.6 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.9 EMT52012.1 - 0.02 15.2 20.9 1.9 8.8 0.3 4.2 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_24 PF13479.6 EMT52012.1 - 0.02 14.6 0.6 0.033 13.9 0.6 1.5 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 EMT52012.1 - 0.029 14.6 19.6 0.17 12.1 4.6 3.6 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family Phage_clamp_A PF16790.5 EMT52012.1 - 0.043 14.3 0.1 0.081 13.4 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage clamp loader A subunit APG17 PF04108.12 EMT52012.1 - 0.1 11.7 19.7 1.2 8.2 8.0 3.2 1 1 1 3 3 3 0 Autophagy protein Apg17 DUF948 PF06103.11 EMT52012.1 - 0.14 12.4 16.1 0.38 11.0 2.3 4.6 2 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CheZ PF04344.13 EMT52012.1 - 0.48 10.3 15.5 2.1 8.2 7.3 2.5 2 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF1657 PF07870.11 EMT52012.1 - 0.61 10.0 4.5 7.1 6.6 0.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1657) Syntaxin-6_N PF09177.11 EMT52012.1 - 0.96 10.0 14.1 6.1 7.5 5.9 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Occludin_ELL PF07303.13 EMT52012.1 - 1.1 10.0 7.3 3.9 8.3 2.2 3.6 2 2 2 4 4 4 0 Occludin homology domain LXG PF04740.12 EMT52012.1 - 1.7 8.3 18.5 0.13 11.9 8.8 2.9 2 1 0 2 2 2 0 LXG domain of WXG superfamily Spc7 PF08317.11 EMT52012.1 - 2.4 6.9 27.6 1 8.2 15.1 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein HMMR_N PF15905.5 EMT52012.1 - 4.7 6.6 24.3 0.32 10.4 12.3 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Med9 PF07544.13 EMT52012.1 - 5.5 7.2 12.3 62 3.8 6.4 4.1 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 KxDL PF10241.9 EMT52012.1 - 8.1 6.8 10.3 1.4 9.3 0.7 3.7 3 2 2 5 5 5 0 Uncharacterized conserved protein DUF1043 PF06295.12 EMT52012.1 - 8.2 6.5 13.5 0.79 9.7 5.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) Peptidase_M14 PF00246.24 EMT52013.1 - 1.3e-21 77.7 0.0 4e-21 76.1 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EMT52013.1 - 0.03 13.4 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Methyltransf_11 PF08241.12 EMT52015.1 - 2.3e-22 79.4 0.0 3.5e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT52015.1 - 5.1e-20 72.0 0.0 8.2e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT52015.1 - 3.7e-17 62.5 0.0 5.1e-17 62.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT52015.1 - 8e-17 61.6 0.0 1.5e-16 60.7 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT52015.1 - 1.3e-12 48.3 0.0 1.8e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT52015.1 - 1.7e-09 37.4 0.0 2.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 EMT52015.1 - 0.00062 19.5 0.0 0.0014 18.3 0.0 1.6 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 EMT52015.1 - 0.00071 19.0 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 EMT52015.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EMT52015.1 - 0.0019 18.2 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EMT52015.1 - 0.0043 16.0 0.0 0.0057 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MF_alpha_N PF05436.11 EMT52015.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus CMAS PF02353.20 EMT52015.1 - 0.052 12.8 0.1 0.13 11.6 0.0 1.6 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase NodS PF05401.11 EMT52015.1 - 0.075 12.6 0.0 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) CheR PF01739.18 EMT52015.1 - 0.14 11.7 0.0 1.4 8.4 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.7 EMT52015.1 - 0.16 11.9 0.0 0.66 9.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Glyoxalase PF00903.25 EMT52016.1 - 4.4e-26 91.6 0.3 3.8e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMT52016.1 - 5.4e-16 58.8 0.0 1.3e-07 31.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EMT52016.1 - 1.2e-12 48.2 0.2 3.5e-11 43.4 0.1 2.5 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EMT52016.1 - 3.6e-08 33.7 0.0 0.12 12.4 0.0 3.3 3 1 0 3 3 3 3 Glyoxalase-like domain 5TM-5TMR_LYT PF07694.12 EMT52017.1 - 2.8e-57 192.9 13.3 4.4e-57 192.3 13.3 1.3 1 0 0 1 1 1 1 5TMR of 5TMR-LYT His_kinase PF06580.13 EMT52017.1 - 2.5e-26 91.8 1.0 4.2e-26 91.1 0.2 1.8 2 0 0 2 2 2 1 Histidine kinase GAF_3 PF13492.6 EMT52017.1 - 9.2e-17 61.6 0.1 2e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EMT52017.1 - 3.6e-07 30.6 0.0 1e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.26 EMT52017.1 - 5.1e-07 30.2 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SpoVT_C PF15714.5 EMT52017.1 - 1.1e-06 28.7 0.1 2.5e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor GAF PF01590.26 EMT52017.1 - 2.9e-05 24.7 0.0 8.4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 GAF domain ECF_trnsprt PF12822.7 EMT52017.1 - 9e-05 22.6 12.8 0.00017 21.7 12.8 1.4 1 0 0 1 1 1 1 ECF transporter, substrate-specific component HATPase_c_2 PF13581.6 EMT52017.1 - 0.00088 19.2 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain ThiW PF09512.10 EMT52017.1 - 0.0025 17.9 8.7 0.006 16.7 8.7 1.7 1 0 0 1 1 1 1 Thiamine-precursor transporter protein (ThiW) HATPase_c_3 PF13589.6 EMT52017.1 - 0.049 13.5 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC_cobalt PF09819.9 EMT52017.1 - 1.6 8.9 15.7 0.1 12.7 7.3 2.5 1 1 1 2 2 2 0 ABC-type cobalt transport system, permease component LytTR PF04397.15 EMT52018.1 - 2.2e-25 88.7 0.0 4.4e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 LytTr DNA-binding domain Response_reg PF00072.24 EMT52018.1 - 1.9e-21 76.3 0.1 3.6e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain CstA PF02554.14 EMT52019.1 - 5.8e-168 558.6 26.7 5.8e-168 558.6 26.7 2.0 2 1 0 2 2 2 1 Carbon starvation protein CstA CstA_5TM PF13722.6 EMT52019.1 - 9.8e-34 116.2 7.5 9.8e-34 116.2 7.5 3.2 3 0 0 3 3 3 1 5TM C-terminal transporter carbon starvation CstA Sel_put PF04328.13 EMT52020.1 - 1.6e-19 69.7 0.5 2e-19 69.4 0.5 1.1 1 0 0 1 1 1 1 Selenoprotein, putative Inositol_P PF00459.25 EMT52021.1 - 5.8e-64 216.2 0.0 6.9e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family GerA PF03323.13 EMT52022.1 - 2.3e-185 616.5 0.4 2.9e-185 616.2 0.4 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein Spore_GerAC PF05504.11 EMT52023.1 - 3.9e-28 98.7 0.2 6.6e-28 98.0 0.2 1.4 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal DUF5006 PF16397.5 EMT52023.1 - 0.079 12.1 0.1 0.16 11.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5006) Spore_permease PF03845.13 EMT52025.1 - 4.2e-41 140.8 26.7 5.1e-41 140.6 26.7 1.1 1 0 0 1 1 1 1 Spore germination protein PTR2 PF00854.21 EMT52026.1 - 2.3e-62 211.1 19.0 7.5e-34 117.2 5.4 2.2 1 1 0 2 2 2 2 POT family MFS_1 PF07690.16 EMT52026.1 - 7.9e-25 87.5 42.5 5.6e-22 78.1 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipase_GDSL_2 PF13472.6 EMT52027.1 - 2.8e-24 86.5 1.1 6.6e-24 85.3 1.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMT52027.1 - 1.3e-09 38.3 0.1 7e-09 35.9 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ribosomal_L10 PF00466.20 EMT52027.1 - 0.0059 16.7 0.0 0.0097 16.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 OSK PF17182.4 EMT52027.1 - 0.0065 15.7 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 OSK domain NPH3 PF03000.14 EMT52027.1 - 0.035 13.8 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 NPH3 family Lipase_GDSL_3 PF14606.6 EMT52027.1 - 0.16 12.1 0.0 0.33 11.0 0.0 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Holin_BhlA PF10960.8 EMT52028.1 - 0.0029 17.6 0.0 0.14 12.2 0.0 2.2 2 0 0 2 2 2 2 BhlA holin family ABC_tran PF00005.27 EMT52029.1 - 7.3e-37 126.9 0.0 9.9e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT52029.1 - 2.9e-12 47.0 0.0 4.5e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT52029.1 - 2.4e-07 30.4 0.1 0.0006 19.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EMT52029.1 - 2.3e-05 24.2 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMT52029.1 - 5.1e-05 23.9 0.1 7.3e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT52029.1 - 0.00011 21.9 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EMT52029.1 - 0.00012 21.0 2.0 0.13 11.0 0.2 3.0 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 EMT52029.1 - 0.00016 22.1 0.1 0.00022 21.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT52029.1 - 0.00031 21.0 0.1 0.00057 20.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EMT52029.1 - 0.00047 20.5 0.0 0.003 17.8 0.0 2.2 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EMT52029.1 - 0.0013 18.6 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EMT52029.1 - 0.0019 17.9 0.5 0.0045 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMT52029.1 - 0.0033 17.6 0.0 0.0086 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 EMT52029.1 - 0.0035 16.1 0.0 1.1 7.8 0.0 2.0 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EMT52029.1 - 0.0064 16.4 0.1 0.012 15.5 0.0 1.5 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EMT52029.1 - 0.0092 16.3 0.4 0.014 15.8 0.3 1.6 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EMT52029.1 - 0.01 14.9 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 EMT52029.1 - 0.011 16.3 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMT52029.1 - 0.011 15.6 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 EMT52029.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 EMT52029.1 - 0.012 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 EMT52029.1 - 0.013 15.2 0.0 0.13 11.9 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 EMT52029.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DEAD PF00270.29 EMT52029.1 - 0.026 14.3 0.1 0.039 13.7 0.1 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.6 EMT52029.1 - 0.031 13.8 0.2 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 EMT52029.1 - 0.033 13.0 0.2 0.38 9.5 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_14 PF13173.6 EMT52029.1 - 0.038 14.0 0.0 0.08 13.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 EMT52029.1 - 0.043 13.3 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EMT52029.1 - 0.047 14.1 0.5 0.44 11.0 0.2 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EMT52029.1 - 0.051 13.1 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EMT52029.1 - 0.055 12.8 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SRPRB PF09439.10 EMT52029.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.17 EMT52029.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DLIC PF05783.11 EMT52029.1 - 0.13 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_5 PF07728.14 EMT52029.1 - 0.14 12.2 0.1 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 EMT52029.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase BPD_transp_1 PF00528.22 EMT52030.1 - 2.6e-22 79.5 9.8 2.6e-22 79.5 9.8 1.4 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component LapA_dom PF06305.11 EMT52030.1 - 0.44 10.4 5.5 1.9 8.4 1.9 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SBP_bac_3 PF00497.20 EMT52031.1 - 6e-62 209.0 0.4 7.2e-62 208.7 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EMT52031.1 - 3.6e-05 23.9 0.0 0.00058 20.0 0.0 2.6 1 1 1 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 EMT52032.1 - 5.5e-62 209.1 0.1 6.4e-62 208.9 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EMT52032.1 - 6.9e-05 23.0 0.0 0.0016 18.6 0.0 2.6 2 1 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Phosphonate-bd PF12974.7 EMT52032.1 - 0.0014 18.2 0.0 0.003 17.2 0.0 1.7 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein TTRAP PF14203.6 EMT52032.1 - 0.0057 16.6 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative tranposon-transfer assisting protein ADH_zinc_N PF00107.26 EMT52032.1 - 0.024 14.6 0.0 3 7.9 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF1059 PF06348.11 EMT52032.1 - 0.14 12.4 0.0 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) Vut_1 PF02592.15 EMT52033.1 - 1.2e-51 175.0 7.3 1.2e-51 175.0 7.3 1.4 2 0 0 2 2 2 1 Putative vitamin uptake transporter DUF4229 PF14012.6 EMT52033.1 - 0.64 10.2 17.2 1.3 9.2 1.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) QueF PF14489.6 EMT52034.1 - 2.1e-28 98.3 0.0 3e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 QueF-like protein QueF_N PF14819.6 EMT52034.1 - 0.0004 20.7 0.0 0.00065 20.0 0.0 1.3 1 0 0 1 1 1 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term GTP_cyclohydroI PF01227.22 EMT52034.1 - 0.04 13.3 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase I Imm1 PF14430.6 EMT52035.1 - 0.0025 18.5 0.0 0.0028 18.3 0.0 1.1 1 0 0 1 1 1 1 Immunity protein Imm1 Mem_trans PF03547.18 EMT52036.1 - 5.9e-22 77.6 25.8 2.8e-15 55.6 2.7 2.1 1 1 1 2 2 2 2 Membrane transport protein DUF3341 PF11821.8 EMT52036.1 - 0.68 9.6 12.1 5.2 6.7 0.0 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3341) Cu_amine_oxidN1 PF07833.11 EMT52037.1 - 3e-18 66.1 0.8 1.1e-10 41.8 0.3 2.8 2 1 1 3 3 3 2 Copper amine oxidase N-terminal domain PrcB_C PF14343.6 EMT52037.1 - 5.5e-13 48.8 0.4 1.1e-12 47.9 0.4 1.5 1 0 0 1 1 1 1 PrcB C-terminal PapC_C PF13953.6 EMT52037.1 - 0.098 12.5 0.2 0.48 10.3 0.0 2.3 2 1 0 2 2 2 0 PapC C-terminal domain PCC_BT PF18140.1 EMT52037.1 - 0.15 12.4 0.6 1.5 9.2 0.5 2.3 1 1 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain ABC_tran PF00005.27 EMT52038.1 - 2.6e-50 170.5 1.8 8.4e-26 91.1 0.0 3.5 4 0 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EMT52038.1 - 7.2e-25 86.8 17.9 2.5e-24 85.1 4.4 3.5 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EMT52038.1 - 3.7e-18 66.4 9.5 7.1e-06 26.0 0.0 4.5 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT52038.1 - 7e-11 42.0 1.0 0.029 13.8 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_tran_CTD PF16326.5 EMT52038.1 - 6e-08 32.8 11.0 6e-08 32.8 11.0 4.1 3 1 0 3 3 3 1 ABC transporter C-terminal domain AAA_22 PF13401.6 EMT52038.1 - 9.2e-07 29.2 1.4 0.028 14.7 0.0 3.9 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 EMT52038.1 - 8.8e-06 25.7 0.2 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EMT52038.1 - 1e-05 25.5 0.2 1.2 8.8 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 EMT52038.1 - 1.3e-05 25.7 0.1 0.12 12.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EMT52038.1 - 2.8e-05 23.8 0.3 0.3 10.9 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT52038.1 - 3.3e-05 24.3 1.4 0.29 11.5 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EMT52038.1 - 0.00013 22.0 0.0 0.85 9.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.22 EMT52038.1 - 0.00015 22.1 0.0 0.24 11.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 EMT52038.1 - 0.00015 22.3 29.7 0.052 14.1 0.2 5.6 3 2 1 4 4 4 2 AAA domain AAA_18 PF13238.6 EMT52038.1 - 0.00017 22.2 0.4 0.22 12.1 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EMT52038.1 - 0.00055 20.2 0.0 1 9.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EMT52038.1 - 0.0012 18.3 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 EMT52038.1 - 0.0017 18.3 0.2 0.17 11.8 0.0 2.9 3 0 0 3 3 2 1 Rad17 P-loop domain SbcCD_C PF13558.6 EMT52038.1 - 0.0019 18.4 0.2 1.4 9.2 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 EMT52038.1 - 0.002 16.9 7.4 0.1 11.2 0.0 4.4 4 1 1 5 5 5 1 AAA domain NACHT PF05729.12 EMT52038.1 - 0.0025 17.7 0.0 2.7 7.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 EMT52038.1 - 0.0046 17.1 5.0 0.99 9.6 0.1 3.3 3 1 0 3 3 2 2 AAA domain AAA_30 PF13604.6 EMT52038.1 - 0.0053 16.5 0.1 1.7 8.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain DUF3584 PF12128.8 EMT52038.1 - 0.0075 13.8 0.1 0.0075 13.8 0.1 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3584) AAA_24 PF13479.6 EMT52038.1 - 0.011 15.5 0.9 2.6 7.7 0.1 2.7 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 EMT52038.1 - 0.011 15.9 0.1 4.9 7.4 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 EMT52038.1 - 0.025 14.2 8.3 0.11 12.0 0.0 4.0 5 1 0 5 5 4 0 AAA domain T2SSE_N PF05157.15 EMT52038.1 - 0.055 13.7 0.3 0.21 11.9 0.3 2.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain AAA_14 PF13173.6 EMT52038.1 - 0.057 13.4 0.8 9.2 6.3 0.0 3.5 4 0 0 4 4 3 0 AAA domain SRP54 PF00448.22 EMT52038.1 - 0.078 12.6 0.4 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 EMT52038.1 - 0.092 12.7 0.5 19 5.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 EMT52038.1 - 0.094 12.5 0.2 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EMT52038.1 - 0.1 12.6 1.2 2.1 8.4 0.0 3.2 3 0 0 3 3 3 0 Dynamin family Viral_helicase1 PF01443.18 EMT52038.1 - 0.12 12.1 0.0 4.5 7.0 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EMT52038.1 - 0.17 11.9 4.1 6.8 6.7 0.1 3.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CLP1_P PF16575.5 EMT52038.1 - 0.19 11.5 0.1 4.2 7.1 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FeoB_N PF02421.18 EMT52038.1 - 0.2 11.2 0.1 5.9 6.4 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 EMT52038.1 - 0.33 10.5 0.9 4.5 6.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DASH_Dad3 PF08656.10 EMT52038.1 - 0.4 10.8 2.9 14 5.9 0.0 3.4 4 0 0 4 4 2 0 DASH complex subunit Dad3 ATPase_2 PF01637.18 EMT52038.1 - 0.51 10.2 2.8 15 5.4 0.0 3.3 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 EMT52038.1 - 0.59 9.9 1.6 30 4.3 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DUF4349 PF14257.6 EMT52038.1 - 0.65 9.4 9.8 0.027 13.9 3.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF87 PF01935.17 EMT52038.1 - 0.71 9.9 3.3 18 5.3 0.0 3.6 4 0 0 4 4 3 0 Helicase HerA, central domain DivIC PF04977.15 EMT52038.1 - 0.83 9.5 13.9 3 7.7 0.2 3.9 3 1 1 4 4 3 0 Septum formation initiator DUF16 PF01519.16 EMT52038.1 - 0.95 10.0 4.4 1.1 9.8 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF16 Occludin_ELL PF07303.13 EMT52038.1 - 1.6 9.5 9.2 2.7 8.8 1.2 3.4 3 0 0 3 3 3 0 Occludin homology domain Spc29 PF17082.5 EMT52038.1 - 3.7 7.3 7.7 0.24 11.2 1.1 2.2 3 0 0 3 3 2 0 Spindle Pole Component 29 Mst1_SARAH PF11629.8 EMT52038.1 - 5.8 7.1 10.5 5.2 7.2 5.0 2.8 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 MFS_1 PF07690.16 EMT52039.1 - 9.9e-60 202.3 61.1 5.7e-48 163.6 33.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT52039.1 - 5.8e-14 51.7 29.4 2.6e-08 33.2 9.9 2.1 1 1 1 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 EMT52039.1 - 6.8e-12 44.7 30.8 3.5e-08 32.4 8.8 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 EMT52039.1 - 2e-08 33.5 9.9 2e-08 33.5 9.9 3.2 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 EMT52039.1 - 5.6e-06 25.0 14.0 8.1e-06 24.5 14.0 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_4 PF06779.14 EMT52039.1 - 9.3e-05 21.9 25.9 0.00012 21.5 25.9 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF2755 PF10954.8 EMT52039.1 - 1.4 8.9 5.9 6.6 6.7 0.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2755) DDE_Tnp_1_assoc PF13808.6 EMT52040.1 - 0.0015 18.5 0.0 2.6 8.1 0.0 2.5 2 1 0 2 2 2 2 DDE_Tnp_1-associated Bac_RepA_C PF18008.1 EMT52040.1 - 0.021 15.2 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 Replication initiator protein A C-terminal domain Prim-Pol PF09250.11 EMT52040.1 - 0.085 13.2 0.0 0.16 12.3 0.0 1.3 1 1 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal DUF910 PF06014.11 EMT52041.1 - 1.2e-15 57.2 0.6 1.3e-15 57.1 0.6 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF910) Methyltransf_25 PF13649.6 EMT52042.1 - 4.5e-05 24.1 0.0 7.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT52042.1 - 0.00015 22.4 0.0 0.00023 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMT52042.1 - 0.00078 19.0 0.0 0.0018 17.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EMT52042.1 - 0.0042 17.7 0.0 0.0065 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EMT52042.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 EMT52042.1 - 0.039 13.7 0.0 0.29 10.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Flu_PB2 PF00604.17 EMT52042.1 - 0.11 10.4 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 SNARE_assoc PF09335.11 EMT52043.1 - 7.9e-20 71.5 9.7 1.8e-19 70.4 5.3 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein Response_reg PF00072.24 EMT52044.1 - 4.3e-31 107.4 0.8 6.6e-31 106.8 0.8 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT52044.1 - 1.2e-29 102.2 0.1 2.7e-29 101.1 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HTH_36 PF13730.6 EMT52044.1 - 0.023 14.7 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 EMT52044.1 - 0.037 13.6 0.0 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EMT52044.1 - 0.057 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HATPase_c PF02518.26 EMT52045.1 - 8e-20 71.4 0.0 2.2e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT52045.1 - 4.8e-15 55.3 0.1 4.8e-15 55.3 0.1 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EMT52045.1 - 8.4e-10 38.9 0.8 2.6e-09 37.3 0.2 2.2 2 0 0 2 2 2 1 HAMP domain HATPase_c_5 PF14501.6 EMT52045.1 - 8.5e-07 28.8 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 GHKL domain DUF4510 PF14971.6 EMT52045.1 - 0.0011 19.3 0.6 0.0026 18.1 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4510) sCache_like PF16736.5 EMT52045.1 - 0.0089 16.1 0.1 0.023 14.8 0.1 1.6 1 0 0 1 1 1 1 Single Cache-like dCache_1 PF02743.18 EMT52045.1 - 0.012 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Cache domain PocR PF10114.9 EMT52045.1 - 0.066 13.0 0.3 0.31 10.8 0.0 2.2 3 0 0 3 3 3 0 Sensory domain found in PocR DUF3600 PF12207.8 EMT52045.1 - 0.094 12.7 0.0 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) CENP-K PF11802.8 EMT52045.1 - 0.1 12.1 2.9 0.13 11.8 0.8 2.2 2 1 0 2 2 2 0 Centromere-associated protein K HATPase_c_2 PF13581.6 EMT52045.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain KASH_CCD PF14662.6 EMT52045.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.6 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH NUDIX PF00293.28 EMT52046.1 - 1.7e-18 66.9 0.1 2e-18 66.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EMT52046.1 - 0.0032 17.4 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4574 PF15141.6 EMT52047.1 - 0.014 15.2 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 LapA_dom PF06305.11 EMT52047.1 - 0.097 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain T2SSM PF04612.12 EMT52047.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Transketolase_N PF00456.21 EMT52048.1 - 1.1e-153 511.1 0.2 1.6e-153 510.6 0.2 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EMT52048.1 - 1.4e-47 161.6 0.9 3.6e-47 160.3 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMT52048.1 - 5.3e-10 39.2 0.1 1.8e-08 34.3 0.0 3.1 3 1 0 3 3 3 1 Transketolase, C-terminal domain E1_dh PF00676.20 EMT52048.1 - 4.7e-07 29.1 0.0 8.9e-06 24.9 0.0 2.1 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EMT52048.1 - 5.7e-06 25.7 0.1 0.0057 15.9 0.4 2.4 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EMT52048.1 - 0.00085 19.1 6.0 0.011 15.6 1.9 3.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transgly PF00912.22 EMT52049.1 - 1.3e-65 220.2 0.0 3.1e-65 219.0 0.0 1.6 2 0 0 2 2 2 1 Transglycosylase Transpeptidase PF00905.22 EMT52049.1 - 2e-40 138.9 2.6 5e-40 137.6 2.6 1.7 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain Beta-lactamase2 PF13354.6 EMT52049.1 - 0.012 15.3 0.1 0.16 11.6 0.1 2.2 1 1 0 1 1 1 0 Beta-lactamase enzyme family YkuD PF03734.14 EMT52051.1 - 4.9e-18 66.0 0.1 9.3e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain TPR_1 PF00515.28 EMT52051.1 - 0.00044 19.9 0.1 0.00099 18.8 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF2633 PF11119.8 EMT52051.1 - 0.0017 18.2 0.9 0.0032 17.3 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2633) TPR_2 PF07719.17 EMT52051.1 - 0.0038 17.2 0.4 0.011 15.8 0.4 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMT52051.1 - 0.031 14.5 0.1 0.095 13.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMT52051.1 - 0.031 14.6 0.6 0.092 13.1 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_21 PF13304.6 EMT52052.1 - 2e-16 60.7 0.0 3.5e-08 33.6 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EMT52052.1 - 2.8e-14 53.6 0.0 6.3e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EMT52052.1 - 1.8e-10 40.6 0.0 2.6e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMT52052.1 - 4.6e-10 40.3 0.0 6.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT52052.1 - 3.2e-06 26.8 0.0 6.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EMT52052.1 - 1.6e-05 25.4 0.0 0.00017 22.1 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EMT52052.1 - 0.00096 19.4 0.1 0.013 15.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EMT52052.1 - 0.0086 14.9 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class NACHT PF05729.12 EMT52052.1 - 0.0097 15.8 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 EMT52052.1 - 0.013 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EMT52052.1 - 0.02 15.3 0.1 0.027 14.9 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 EMT52052.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EMT52052.1 - 0.07 13.7 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EMT52052.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MukB PF04310.12 EMT52052.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 MukB N-terminal GTP_EFTU PF00009.27 EMT52052.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 EMT52052.1 - 0.18 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 EMT52052.1 - 0.18 11.0 0.0 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) DUF1963 PF09234.10 EMT52053.1 - 3.3e-44 151.9 0.0 4.4e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) Choline_transpo PF04515.12 EMT52054.1 - 0.036 13.3 0.0 0.036 13.3 0.0 1.0 1 0 0 1 1 1 0 Plasma-membrane choline transporter LapA_dom PF06305.11 EMT52054.1 - 0.04 13.7 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4083 PF13314.6 EMT52054.1 - 0.062 13.3 8.0 0.15 12.0 8.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4083) 7TM_transglut PF14402.6 EMT52054.1 - 0.089 12.2 1.3 0.1 12.1 1.3 1.2 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Methyltransf_4 PF02390.17 EMT52055.1 - 8.9e-49 165.3 0.1 1e-48 165.1 0.1 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 EMT52055.1 - 4e-09 36.4 0.0 1.3e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT52055.1 - 3.1e-08 34.2 0.0 7.3e-08 33.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT52055.1 - 6.3e-08 33.3 0.0 2.8e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT52055.1 - 1e-05 26.1 0.0 3.3e-05 24.5 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 EMT52055.1 - 0.00014 21.6 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 EMT52055.1 - 0.0031 17.4 0.0 0.014 15.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain TssO PF17561.2 EMT52055.1 - 0.0035 17.5 0.1 0.0077 16.3 0.0 1.6 2 0 0 2 2 2 1 Type VI secretion system, TssO MTS PF05175.14 EMT52055.1 - 0.006 16.1 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EMT52055.1 - 0.052 12.8 0.0 0.25 10.6 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Inhibitor_I29 PF08246.12 EMT52055.1 - 0.081 13.4 0.7 0.081 13.4 0.7 1.7 2 0 0 2 2 1 0 Cathepsin propeptide inhibitor domain (I29) Methyltransf_32 PF13679.6 EMT52055.1 - 0.097 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SSrecog PF03531.14 EMT52055.1 - 0.11 12.4 0.7 0.24 11.3 0.7 1.5 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) Methyltransf_2 PF00891.18 EMT52055.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain NLPC_P60 PF00877.19 EMT52056.1 - 6.7e-27 93.6 0.1 8.6e-27 93.2 0.1 1.1 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C92 PF05708.12 EMT52056.1 - 1.9e-09 37.8 0.1 8e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family CHAP PF05257.16 EMT52056.1 - 0.0033 18.0 0.0 0.0063 17.1 0.0 1.5 1 0 0 1 1 1 1 CHAP domain Amidase_5 PF05382.13 EMT52056.1 - 0.03 14.2 0.5 0.089 12.7 0.5 1.8 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase SIS PF01380.22 EMT52057.1 - 2.6e-17 62.9 0.1 4.3e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 EMT52057.1 - 9.7e-14 51.1 0.3 3e-13 49.5 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family SBP_bac_5 PF00496.22 EMT52058.1 - 9.9e-100 334.1 2.9 1.2e-99 333.9 2.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 EMT52059.1 - 1.6e-43 148.6 11.6 1.6e-43 148.6 11.6 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF373 PF04123.13 EMT52059.1 - 2.8 7.3 9.1 0.44 10.0 2.3 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF373) Sigma_reg_N PF13800.6 EMT52059.1 - 3.2 8.1 6.3 3.6 7.9 0.0 3.4 4 0 0 4 4 4 0 Sigma factor regulator N-terminal BPD_transp_1 PF00528.22 EMT52060.1 - 3.7e-31 108.3 14.5 6.2e-31 107.6 12.3 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT52060.1 - 5.7e-10 39.0 0.1 5.7e-10 39.0 0.1 4.4 6 0 0 6 6 6 1 N-terminal TM domain of oligopeptide transport permease C MR_MLE_C PF13378.6 EMT52061.1 - 1.2e-44 152.5 0.0 2.1e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EMT52061.1 - 5.5e-13 49.2 0.0 9.6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Enolase_C PF00113.22 EMT52061.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain MAAL_C PF07476.11 EMT52061.1 - 0.025 13.7 0.0 0.052 12.7 0.0 1.6 1 1 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus His_biosynth PF00977.21 EMT52061.1 - 0.12 11.8 0.0 15 4.9 0.0 2.7 2 1 0 3 3 3 0 Histidine biosynthesis protein Peptidase_M20 PF01546.28 EMT52062.1 - 1e-22 80.8 0.7 1.4e-22 80.4 0.7 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT52062.1 - 1.1e-13 51.0 0.1 2.3e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT52062.1 - 0.08 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 ABC_tran PF00005.27 EMT52063.1 - 2.3e-29 102.7 0.0 3.5e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT52063.1 - 4.2e-22 78.5 0.2 7.4e-22 77.7 0.2 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT52063.1 - 8.5e-07 29.1 0.2 4.8e-06 26.6 0.0 1.9 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT52063.1 - 8.1e-06 25.4 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EMT52063.1 - 0.13 11.0 0.1 0.41 9.4 0.1 1.7 1 1 0 1 1 1 0 Predicted ATPase of the ABC class AAA_22 PF13401.6 EMT52063.1 - 0.17 12.2 1.5 3.4 7.9 1.5 2.2 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EMT52063.1 - 0.2 11.1 0.7 0.94 8.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 EMT52064.1 - 9.2e-32 110.4 0.0 1.2e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT52064.1 - 4.7e-18 65.5 0.4 8.4e-18 64.7 0.4 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT52064.1 - 1.8e-06 28.0 1.5 0.00062 19.7 0.5 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT52064.1 - 0.0002 20.9 0.0 0.00036 20.0 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMT52064.1 - 0.0014 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT52064.1 - 0.002 18.4 1.2 0.033 14.5 1.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT52064.1 - 0.0061 17.0 0.1 0.0097 16.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EMT52064.1 - 0.041 13.9 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EMT52064.1 - 0.11 12.9 0.0 0.22 12.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 EMT52064.1 - 0.16 11.6 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 EMT52064.1 - 0.17 11.8 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase tRNA_lig_kinase PF08303.11 EMT52064.1 - 0.19 11.8 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain AAA_7 PF12775.7 EMT52064.1 - 0.23 11.0 0.1 0.36 10.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MaoC_dehydratas PF01575.19 EMT52067.1 - 1.8e-06 27.5 0.1 6.8e-06 25.7 0.1 1.9 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EMT52067.1 - 1.7e-05 24.9 0.2 0.00022 21.3 0.2 2.2 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 EMT52067.1 - 0.0037 17.6 0.0 0.0054 17.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily ILVD_EDD PF00920.21 EMT52068.1 - 4.4e-230 764.7 0.2 4.9e-230 764.5 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family 4HBT PF03061.22 EMT52069.1 - 1.1e-17 64.2 0.0 1.5e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EMT52069.1 - 3.9e-09 36.7 0.0 5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 EMT52069.1 - 0.0038 17.5 0.0 0.0053 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Inositol_P PF00459.25 EMT52071.1 - 7.5e-49 166.7 0.0 8.3e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family GAD-like PF08887.11 EMT52071.1 - 0.082 12.7 0.0 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 GAD-like domain Ion_trans_2 PF07885.16 EMT52072.1 - 6.3e-17 61.3 6.8 6.3e-17 61.3 6.8 2.2 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EMT52072.1 - 6.5e-17 61.6 12.4 1.7e-16 60.2 12.4 1.6 1 1 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 EMT52072.1 - 0.2 11.5 2.5 0.61 9.9 2.5 2.0 1 1 0 1 1 1 0 Ligand-gated ion channel HSP9_HSP12 PF04119.12 EMT52073.1 - 0.26 11.7 2.5 0.4 11.1 0.1 2.3 2 0 0 2 2 2 0 Heat shock protein 9/12 FtsK_SpoIIIE PF01580.18 EMT52074.1 - 1.6e-63 214.3 0.9 4.9e-47 160.3 0.0 3.0 2 1 1 3 3 3 2 FtsK/SpoIIIE family FtsK_alpha PF17854.1 EMT52074.1 - 9.3e-33 112.4 0.3 2.3e-32 111.1 0.3 1.7 1 0 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 EMT52074.1 - 3.9e-25 87.4 0.5 1.1e-24 86.0 0.0 2.1 2 0 0 2 2 2 1 Ftsk gamma domain AAA_10 PF12846.7 EMT52074.1 - 0.00014 20.9 0.0 0.0032 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.17 EMT52074.1 - 0.00014 22.1 0.2 0.00065 19.9 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 EMT52074.1 - 0.0028 18.0 0.0 0.0081 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Adeno_IVa2 PF02456.15 EMT52074.1 - 0.015 14.1 0.1 0.036 12.9 0.1 1.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_29 PF13555.6 EMT52074.1 - 0.059 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 EMT52074.1 - 0.085 11.8 0.0 0.35 9.7 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 EMT52074.1 - 0.093 12.5 0.1 0.29 10.9 0.0 1.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase AIMP2_LysRS_bd PF16780.5 EMT52076.1 - 0.059 13.1 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain DUF5517 PF17639.2 EMT52076.1 - 0.078 13.3 0.0 0.083 13.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5517) AA_kinase PF00696.28 EMT52077.1 - 7e-39 133.9 0.0 1.6e-38 132.6 0.0 1.6 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 EMT52077.1 - 1e-06 28.4 0.2 4.4e-05 23.1 0.0 3.2 3 1 1 4 4 4 1 ACT domain ACT_7 PF13840.6 EMT52077.1 - 2.5e-06 27.2 0.1 5.7e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 ACT domain PALP PF00291.25 EMT52078.1 - 2.5e-57 194.5 0.7 3.3e-57 194.2 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TPR_4 PF07721.14 EMT52078.1 - 0.95 10.3 3.6 15 6.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Sigma54_activat PF00158.26 EMT52079.1 - 1.1e-68 230.2 0.0 2.4e-68 229.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT52079.1 - 1.3e-22 80.4 0.0 3.7e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain GAF_2 PF13185.6 EMT52079.1 - 1.7e-07 31.6 0.0 3.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 GAF domain AAA_5 PF07728.14 EMT52079.1 - 3.7e-06 27.0 0.1 1.7e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EMT52079.1 - 6.2e-06 26.7 0.0 1.7e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_8 PF02954.19 EMT52079.1 - 1.2e-05 25.0 1.0 4.2e-05 23.2 1.0 2.0 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family GAF PF01590.26 EMT52079.1 - 0.00027 21.6 0.2 0.0025 18.5 0.1 2.5 2 0 0 2 2 2 1 GAF domain Mg_chelatase PF01078.21 EMT52079.1 - 0.00031 20.2 0.3 0.015 14.7 0.3 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Bep_C_terminal PF17841.1 EMT52079.1 - 0.0047 17.1 0.8 0.023 14.9 0.4 2.2 2 0 0 2 2 2 1 BID domain of Bartonella effector protein (Bep) MCM PF00493.23 EMT52079.1 - 0.0068 15.5 0.0 0.08 12.0 0.0 2.3 1 1 0 1 1 1 1 MCM P-loop domain HTH_Crp_2 PF13545.6 EMT52079.1 - 0.0073 16.3 0.3 0.18 11.8 0.1 3.0 2 1 1 3 3 3 1 Crp-like helix-turn-helix domain AAA_30 PF13604.6 EMT52079.1 - 0.015 15.0 0.1 0.11 12.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMT52079.1 - 0.038 14.4 0.4 0.14 12.5 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 EMT52079.1 - 0.041 13.4 0.0 0.12 11.9 0.0 1.7 1 1 1 2 2 2 0 P-loop containing dynein motor region HTH_23 PF13384.6 EMT52079.1 - 0.045 13.6 1.0 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_17 PF12728.7 EMT52079.1 - 0.071 13.3 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain RWP-RK PF02042.15 EMT52079.1 - 0.089 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 RWP-RK domain DUF134 PF02001.16 EMT52079.1 - 0.12 12.9 0.0 0.42 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF134 SpoVT_C PF15714.5 EMT52079.1 - 0.13 12.3 0.1 0.6 10.2 0.1 2.2 1 1 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor AAA_19 PF13245.6 EMT52079.1 - 0.72 10.2 2.6 6.1 7.2 0.1 3.0 3 1 0 3 3 2 0 AAA domain HTH_IclR PF09339.10 EMT52079.1 - 0.87 9.4 6.2 12 5.8 0.1 3.9 4 0 0 4 4 4 0 IclR helix-turn-helix domain Peptidase_S24 PF00717.23 EMT52080.1 - 1.3e-12 47.5 1.2 1.2e-10 41.1 0.8 2.5 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EMT52080.1 - 2.9e-09 36.8 0.0 4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 HTH_18 PF12833.7 EMT52081.1 - 6.8e-19 67.9 2.4 1.6e-18 66.7 1.9 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EMT52081.1 - 8e-14 51.3 0.1 1.8e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_31 PF13560.6 EMT52081.1 - 1.1e-06 28.9 0.2 0.02 15.2 0.7 2.8 1 1 1 2 2 2 2 Helix-turn-helix domain Response_reg PF00072.24 EMT52081.1 - 3.5e-06 27.2 0.0 8.6e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain Urocanase_C PF17392.2 EMT52082.1 - 1.5e-93 311.7 0.1 2.9e-93 310.8 0.1 1.5 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 EMT52082.1 - 7.2e-92 306.8 0.1 1.1e-91 306.1 0.1 1.3 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 EMT52082.1 - 2.1e-60 202.0 0.0 3.5e-60 201.3 0.0 1.4 1 0 0 1 1 1 1 Urocanase N-terminal domain PPR_2 PF13041.6 EMT52082.1 - 0.014 15.6 0.0 0.085 13.1 0.0 2.4 2 0 0 2 2 2 0 PPR repeat family Amidohydro_1 PF01979.20 EMT52083.1 - 6.5e-20 71.7 4.6 7.5e-19 68.2 4.6 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMT52083.1 - 9.1e-19 68.3 5.5 2.7e-09 37.0 1.1 2.3 1 1 1 2 2 2 2 Amidohydrolase family Gate PF07670.14 EMT52084.1 - 8.7e-09 35.7 5.1 8.7e-09 35.7 5.1 3.5 4 1 0 4 4 4 1 Nucleoside recognition GDPD PF03009.17 EMT52085.1 - 6.3e-22 78.5 0.0 8.5e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DAGK_cat PF00781.24 EMT52085.1 - 0.079 12.6 0.0 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain G3P_antiterm PF04309.12 EMT52086.1 - 1.3e-60 203.8 0.0 1.4e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 EMT52086.1 - 0.0051 16.3 0.0 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 EMT52086.1 - 0.041 13.3 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DAO PF01266.24 EMT52087.1 - 1.2e-54 186.2 0.0 1.8e-54 185.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EMT52087.1 - 2.7e-26 91.9 0.0 7e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EMT52087.1 - 1.8e-05 24.0 2.1 0.0032 16.6 0.7 2.5 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 EMT52087.1 - 0.00031 19.9 0.9 0.066 12.3 0.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EMT52087.1 - 0.00061 19.1 1.6 0.0017 17.7 1.6 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMT52087.1 - 0.0015 18.0 4.4 0.0072 15.7 4.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMT52087.1 - 0.0023 18.1 0.3 0.0068 16.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMT52087.1 - 0.017 15.6 1.6 0.024 15.2 0.3 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EMT52087.1 - 0.025 14.5 0.6 0.048 13.5 0.6 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EMT52087.1 - 0.048 12.9 0.5 0.24 10.6 0.5 1.8 1 1 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EMT52087.1 - 0.1 11.7 1.9 1.2 8.1 0.2 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein EamA PF00892.20 EMT52088.1 - 6.2e-28 97.7 41.8 1.3e-20 73.9 14.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family LysR_substrate PF03466.20 EMT52089.1 - 1.6e-45 155.1 0.1 2e-45 154.7 0.1 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT52089.1 - 6.2e-19 67.7 0.0 1.7e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Aldo_ket_red PF00248.21 EMT52090.1 - 6.9e-57 192.9 0.1 1.6e-44 152.3 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family ATPgrasp_YheCD PF14398.6 EMT52091.1 - 4.1e-56 190.1 0.1 5.1e-56 189.8 0.1 1.0 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EMT52091.1 - 5.9e-10 38.9 0.0 0.00015 21.1 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp TTL PF03133.15 EMT52091.1 - 2.4e-07 30.2 0.0 0.00046 19.4 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family GSH-S_ATP PF02955.16 EMT52091.1 - 9.6e-05 21.9 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain CP_ATPgrasp_2 PF14403.6 EMT52091.1 - 0.00027 20.0 0.1 0.035 13.0 0.0 2.4 1 1 2 3 3 3 3 Circularly permuted ATP-grasp type 2 ATP-grasp_3 PF02655.14 EMT52091.1 - 0.0031 17.6 0.0 0.0082 16.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Imm-NTF2-2 PF15631.6 EMT52091.1 - 0.067 13.5 0.0 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 NTF2 fold immunity protein R2K_3 PF14243.6 EMT52091.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 IclR PF01614.18 EMT52092.1 - 1.8e-23 82.8 0.1 3.4e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EMT52092.1 - 5e-16 58.2 0.3 1e-15 57.2 0.3 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.22 EMT52092.1 - 8.7e-07 28.8 0.1 1.7e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EMT52092.1 - 0.00036 20.3 0.1 0.00081 19.2 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 EMT52092.1 - 0.00076 19.4 0.1 0.0017 18.3 0.1 1.6 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 EMT52092.1 - 0.0057 16.4 0.0 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 EMT52092.1 - 0.006 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EMT52092.1 - 0.012 15.4 0.0 0.043 13.7 0.0 1.9 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EMT52092.1 - 0.014 15.8 0.1 0.046 14.1 0.0 1.9 2 0 0 2 2 1 0 Transcriptional regulator HTH_36 PF13730.6 EMT52092.1 - 0.016 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 EMT52092.1 - 0.021 14.6 0.1 0.087 12.6 0.1 1.9 2 0 0 2 2 2 0 LexA DNA binding domain Fe_dep_repress PF01325.19 EMT52092.1 - 0.024 14.8 0.0 0.35 11.1 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Penicillinase_R PF03965.16 EMT52092.1 - 0.03 14.7 0.0 0.075 13.4 0.0 1.6 1 0 0 1 1 1 0 Penicillinase repressor HTH_38 PF13936.6 EMT52092.1 - 0.048 13.4 0.4 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_20 PF12840.7 EMT52092.1 - 0.081 13.0 0.2 0.24 11.5 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EMT52092.1 - 0.082 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain FeoC PF09012.10 EMT52092.1 - 0.12 12.5 0.3 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 FeoC like transcriptional regulator Glycos_transf_1 PF00534.20 EMT52093.1 - 1.4e-05 24.7 0.0 4.2e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT52093.1 - 0.0016 18.9 0.0 0.0038 17.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EMT52093.1 - 0.0056 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 TetR_N PF00440.23 EMT52094.1 - 3.5e-10 39.5 0.3 3.8e-09 36.2 0.0 2.5 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 EMT52094.1 - 0.0065 16.8 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_13 PF16925.5 EMT52094.1 - 0.009 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF5055 PF16478.5 EMT52094.1 - 0.038 14.2 0.0 0.28 11.4 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5055) HTH_Tnp_1_2 PF13022.6 EMT52094.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.6 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase DUF4188 PF13826.6 EMT52095.1 - 2.2e-31 108.6 0.1 2.6e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 EMT52095.1 - 1.8e-06 27.6 0.1 2.3e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase MCPsignal PF00015.21 EMT52096.1 - 7.9e-28 97.4 13.8 7.9e-28 97.4 13.8 2.1 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_4 PF08448.10 EMT52096.1 - 9.6e-11 41.9 0.0 2.2e-10 40.8 0.0 1.6 2 0 0 2 2 1 1 PAS fold PAS_9 PF13426.7 EMT52096.1 - 1.9e-10 40.9 0.0 5.1e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EMT52096.1 - 6.8e-08 32.7 0.0 1.2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EMT52096.1 - 4.1e-07 30.0 0.0 1.2e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 PAS fold DUF1664 PF07889.12 EMT52096.1 - 0.0025 17.8 15.3 0.011 15.7 6.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) EzrA PF06160.12 EMT52096.1 - 0.0061 14.8 1.1 0.0061 14.8 1.1 2.1 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA PAS_8 PF13188.7 EMT52096.1 - 0.019 15.0 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 PAS domain DUF948 PF06103.11 EMT52096.1 - 0.025 14.8 17.8 0.55 10.5 4.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 EMT52096.1 - 0.041 12.8 12.7 0.047 12.6 10.1 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Sec34 PF04136.15 EMT52096.1 - 0.057 13.3 7.6 1.8 8.4 1.2 2.5 2 0 0 2 2 2 0 Sec34-like family MEKHLA PF08670.11 EMT52096.1 - 0.071 13.0 0.6 0.2 11.6 0.0 2.0 2 1 0 2 2 2 0 MEKHLA domain Fib_alpha PF08702.10 EMT52096.1 - 0.13 12.5 11.8 0.12 12.6 1.2 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DASH_Dad2 PF08654.10 EMT52096.1 - 0.18 12.2 12.7 1.1 9.7 1.9 2.6 1 1 1 2 2 2 0 DASH complex subunit Dad2 Syntaxin-6_N PF09177.11 EMT52096.1 - 0.27 11.8 8.4 1.2 9.8 2.4 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal APG17 PF04108.12 EMT52096.1 - 0.35 9.9 15.5 0.11 11.6 6.3 2.1 1 1 0 2 2 2 0 Autophagy protein Apg17 Laminin_II PF06009.12 EMT52096.1 - 0.68 9.9 19.1 1.9 8.5 6.1 2.2 2 0 0 2 2 2 0 Laminin Domain II COG5 PF10392.9 EMT52096.1 - 0.74 10.0 11.6 0.18 12.0 2.0 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 BAR_3 PF16746.5 EMT52096.1 - 0.77 9.4 9.0 0.82 9.3 2.4 2.2 2 0 0 2 2 2 0 BAR domain of APPL family COG2 PF06148.11 EMT52096.1 - 1.7 8.8 7.9 3.3 7.8 0.6 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 T7SS_ESX_EspC PF10824.8 EMT52096.1 - 2 9.0 10.2 0.23 12.0 2.6 2.6 2 1 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm IFT57 PF10498.9 EMT52096.1 - 2.1 7.2 12.2 1.6 7.6 3.5 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Vps53_N PF04100.12 EMT52096.1 - 3.6 6.4 12.4 0.31 10.0 2.9 2.2 2 0 0 2 2 2 0 Vps53-like, N-terminal Cauli_AT PF03233.13 EMT52096.1 - 4.4 7.2 7.0 3 7.7 2.7 2.3 2 0 0 2 2 2 0 Aphid transmission protein BLOC1_2 PF10046.9 EMT52096.1 - 4.6 7.6 12.8 7.7 6.9 1.1 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SKA1 PF07160.12 EMT52096.1 - 6.9 6.4 13.4 0.58 10.0 2.1 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 YabA PF06156.13 EMT52096.1 - 7.3 7.3 8.5 26 5.5 0.2 2.7 2 2 0 2 2 2 0 Initiation control protein YabA EPO_TPO PF00758.18 EMT52096.1 - 8 6.5 8.0 16 5.5 1.5 2.2 1 1 0 2 2 2 0 Erythropoietin/thrombopoietin Cluap1 PF10234.9 EMT52096.1 - 8.9 5.6 13.7 9.2 5.6 4.0 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 SNF2_assoc PF08455.10 EMT52097.1 - 1.3e-94 317.3 0.0 3.1e-94 316.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial SNF2 helicase associated SNF2_N PF00176.23 EMT52097.1 - 2.4e-52 177.8 0.0 4.3e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMT52097.1 - 2.5e-22 79.3 0.0 2.9e-21 75.9 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SWIM PF04434.17 EMT52097.1 - 0.0043 16.7 0.5 0.01 15.5 0.5 1.6 1 0 0 1 1 1 1 SWIM zinc finger SWI2_SNF2 PF18766.1 EMT52097.1 - 0.032 13.9 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 EMT52097.1 - 0.051 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF3892 PF13031.6 EMT52098.1 - 2.2e-16 60.2 0.1 3.2e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3892) Aconitase PF00330.20 EMT52100.1 - 3.6e-183 609.8 0.0 4.5e-183 609.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EMT52100.1 - 8.1e-47 158.8 0.0 1.5e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ABC_membrane PF00664.23 EMT52101.1 - 1.2e-47 162.9 13.4 1.5e-47 162.6 13.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMT52101.1 - 5.8e-36 124.0 0.0 1.5e-35 122.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT52101.1 - 8.8e-07 28.6 0.1 0.0047 16.4 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT52101.1 - 0.0001 22.2 0.1 0.003 17.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT52101.1 - 0.00015 21.5 0.1 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT52101.1 - 0.001 19.6 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT52101.1 - 0.0012 19.2 0.0 0.0032 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 EMT52101.1 - 0.0043 15.9 0.0 1.3 7.7 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 EMT52101.1 - 0.0048 16.6 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMT52101.1 - 0.005 17.1 1.2 0.084 13.2 1.2 2.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EMT52101.1 - 0.0057 17.1 0.1 0.2 12.1 0.1 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_membrane_3 PF13748.6 EMT52101.1 - 0.0089 15.3 10.2 0.0095 15.2 1.1 2.9 2 1 1 3 3 3 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 EMT52101.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 EMT52101.1 - 0.033 14.4 0.1 0.083 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMT52101.1 - 0.05 12.9 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Arteri_Gl PF00951.18 EMT52101.1 - 0.067 13.0 0.6 0.19 11.5 0.6 1.7 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein NB-ARC PF00931.22 EMT52101.1 - 0.1 11.7 0.2 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.6 EMT52101.1 - 0.19 12.0 0.3 1.7 8.9 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Response_reg PF00072.24 EMT52102.1 - 1.1e-32 112.5 0.2 1.5e-32 112.0 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT52102.1 - 1.2e-23 83.0 0.0 2.2e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal SSXRD PF09514.10 EMT52102.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 SSXRD motif HATPase_c PF02518.26 EMT52103.1 - 6e-31 107.3 0.6 1.5e-30 106.0 0.6 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT52103.1 - 1.3e-15 57.2 1.6 1.3e-15 57.2 1.6 2.3 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EMT52103.1 - 0.00038 20.8 0.0 0.00088 19.6 0.0 1.6 1 0 0 1 1 1 1 HAMP domain HATPase_c_5 PF14501.6 EMT52103.1 - 0.011 15.6 0.1 0.048 13.6 0.0 1.9 2 0 0 2 2 2 0 GHKL domain HATPase_c_2 PF13581.6 EMT52103.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PurA PF04845.13 EMT52103.1 - 0.06 12.7 0.1 0.088 12.1 0.1 1.2 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein Exonuc_VII_L PF02601.15 EMT52103.1 - 0.1 12.1 0.8 0.13 11.8 0.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HATPase_c_3 PF13589.6 EMT52103.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SOR_SNZ PF01680.17 EMT52103.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 SOR/SNZ family DUF2975 PF11188.8 EMT52103.1 - 0.21 11.5 0.7 0.45 10.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF1451 PF07295.11 EMT52103.1 - 0.25 11.4 1.1 0.37 10.8 1.1 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain ARA70 PF12489.8 EMT52103.1 - 0.67 10.1 5.1 0.2 11.8 1.9 1.7 2 0 0 2 2 2 0 Nuclear coactivator Vma12 PF11712.8 EMT52103.1 - 3 7.9 4.0 0.98 9.5 0.8 1.7 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ThiF PF00899.21 EMT52104.1 - 3.4e-64 216.5 0.0 4.5e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 EMT52104.1 - 0.0017 18.8 0.1 0.0077 16.6 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EMT52104.1 - 0.0069 16.5 0.1 0.018 15.1 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EMT52104.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EMT52104.1 - 0.02 14.9 0.1 0.051 13.6 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EMT52104.1 - 0.035 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 EMT52104.1 - 0.049 14.0 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2072 PF09845.9 EMT52104.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein MoaE PF02391.17 EMT52105.1 - 1.3e-37 128.6 0.6 1.8e-37 128.1 0.6 1.2 1 0 0 1 1 1 1 MoaE protein ThiS PF02597.20 EMT52105.1 - 1.7e-19 70.2 0.0 7.2e-19 68.2 0.0 2.1 3 0 0 3 3 3 1 ThiS family Lambda_tail_I PF06805.12 EMT52105.1 - 0.13 12.6 0.0 0.74 10.2 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I MoaC PF01967.21 EMT52106.1 - 1.5e-56 190.3 5.2 1.7e-56 190.1 5.2 1.0 1 0 0 1 1 1 1 MoaC family MFS_1 PF07690.16 EMT52107.1 - 3.8e-34 118.2 55.3 5.5e-22 78.2 32.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_1_2 PF00155.21 EMT52108.1 - 1.1e-58 199.2 0.0 1.3e-58 199.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 EMT52110.1 - 4.2e-38 131.5 0.0 4.8e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EMT52110.1 - 5.9e-13 48.4 0.0 7.8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 EMT52110.1 - 0.074 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 EMT52110.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III Linocin_M18 PF04454.12 EMT52111.1 - 5.4e-84 281.5 0.0 6e-84 281.3 0.0 1.0 1 0 0 1 1 1 1 Encapsulating protein for peroxidase DUF2184 PF09950.9 EMT52111.1 - 0.0064 15.9 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2184) UvrD_C PF13361.6 EMT52112.1 - 0.047 13.1 0.2 0.077 12.4 0.2 1.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2325 PF10087.9 EMT52113.1 - 2.8e-18 65.8 0.1 3.3e-18 65.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2325) RecU PF03838.14 EMT52114.1 - 0.098 12.7 0.0 0.1 12.6 0.0 1.0 1 0 0 1 1 1 0 Recombination protein U Trypsin_2 PF13365.6 EMT52115.1 - 4.4e-11 43.9 0.0 5.5e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EMT52115.1 - 4.7e-08 33.1 0.0 5.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 EMT52115.1 - 0.0012 17.6 0.1 0.0013 17.5 0.1 1.0 1 0 0 1 1 1 1 Peptidase S46 Peptidase_S7 PF00949.21 EMT52115.1 - 0.037 13.9 0.2 0.052 13.4 0.1 1.5 1 1 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Resolvase PF00239.21 EMT52116.1 - 5.2e-42 143.4 1.2 5.2e-42 143.4 1.2 1.9 2 0 0 2 2 2 1 Resolvase, N terminal domain Recombinase PF07508.13 EMT52116.1 - 1.3e-27 96.2 0.0 4e-27 94.7 0.0 1.9 1 0 0 1 1 1 1 Recombinase Zn_ribbon_recom PF13408.6 EMT52116.1 - 2.9e-12 46.9 1.3 6.2e-12 45.9 1.3 1.6 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain HxlR PF01638.17 EMT52117.1 - 4.8e-33 112.9 0.5 5.7e-33 112.6 0.5 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 EMT52117.1 - 0.0033 17.3 0.0 0.0048 16.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 EMT52117.1 - 0.033 14.4 0.0 0.045 13.9 0.0 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain Replic_Relax PF13814.6 EMT52117.1 - 0.066 13.3 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation HTH_12 PF08461.10 EMT52117.1 - 0.069 13.1 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain ATPgrasp_YheCD PF14398.6 EMT52118.1 - 3.5e-80 269.0 0.0 4.2e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EMT52118.1 - 1.3e-06 27.9 0.0 0.0062 15.8 0.0 2.4 1 1 1 2 2 2 2 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 EMT52118.1 - 0.0065 15.9 0.0 0.13 11.7 0.0 2.4 2 1 0 2 2 2 1 Prokaryotic glutathione synthetase, ATP-grasp domain TTL PF03133.15 EMT52118.1 - 0.076 12.1 0.0 0.3 10.2 0.0 1.8 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family Trypsin_2 PF13365.6 EMT52119.1 - 3.9e-15 57.1 0.0 7.2e-15 56.2 0.0 1.4 2 0 0 2 2 2 1 Trypsin-like peptidase domain PadR PF03551.14 EMT52120.1 - 2.8e-16 59.2 0.0 4.3e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 EMT52120.1 - 9.1e-08 32.2 0.0 1.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain Vir_act_alpha_C PF10400.9 EMT52120.1 - 6.4e-05 23.6 0.2 9.6e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Virulence activator alpha C-term HTH_27 PF13463.6 EMT52120.1 - 0.0014 19.1 0.0 0.0023 18.4 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain RTP PF02334.16 EMT52120.1 - 0.0028 18.3 0.2 0.0068 17.0 0.0 1.6 2 0 0 2 2 2 1 Replication terminator protein HxlR PF01638.17 EMT52120.1 - 0.003 17.4 0.1 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 HxlR-like helix-turn-helix AphA_like PF14557.6 EMT52120.1 - 0.0078 15.9 0.0 0.01 15.6 0.0 1.0 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator Med15_fungi PF05397.12 EMT52120.1 - 0.019 15.2 0.2 0.026 14.8 0.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 15 TrmB PF01978.19 EMT52120.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 EMT52120.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Peptidase_M24 PF00557.24 EMT52120.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M24 Peptidase_M29 PF02073.15 EMT52121.1 - 5.2e-59 200.0 0.0 6e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) Zn_Tnp_IS1595 PF12760.7 EMT52122.1 - 0.023 14.7 0.6 1.6 8.8 0.7 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain P2 PF07194.11 EMT52123.1 - 0.0051 16.8 0.5 0.0076 16.3 0.5 1.2 1 0 0 1 1 1 1 P2 response regulator binding domain DUF5406 PF17400.2 EMT52123.1 - 0.029 14.8 0.6 0.055 13.9 0.5 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5406) FANCL_C PF11793.8 EMT52123.1 - 0.036 14.2 0.2 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain DUF4404 PF14357.6 EMT52123.1 - 1.4 9.6 6.4 0.47 11.1 3.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF2847 PF11009.8 EMT52124.1 - 5.3e-34 116.2 0.1 5.9e-34 116.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Redoxin PF08534.10 EMT52124.1 - 0.031 14.0 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Redoxin Cpta_toxin PF07254.12 EMT52124.1 - 0.036 14.0 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system FtsA PF14450.6 EMT52125.1 - 5.2e-13 49.3 0.3 2e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Cell division protein FtsA PilM_2 PF11104.8 EMT52125.1 - 2.7e-10 39.8 0.3 4.7e-07 29.2 0.3 3.0 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; Ub-Mut7C PF14451.6 EMT52125.1 - 1.7e-07 31.0 0.1 1.5 8.7 0.0 5.9 6 0 0 6 6 6 2 Mut7-C ubiquitin MreB_Mbl PF06723.13 EMT52125.1 - 6.2e-07 28.5 4.4 6.4e-05 21.9 4.4 2.6 1 1 0 1 1 1 1 MreB/Mbl protein DDR PF08841.10 EMT52125.1 - 0.002 17.2 4.6 0.0021 17.1 0.3 2.8 3 0 0 3 3 3 1 Diol dehydratase reactivase ATPase-like domain DAHP_synth_1 PF00793.20 EMT52126.1 - 1.1e-79 267.1 0.0 1.6e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family CM_2 PF01817.21 EMT52126.1 - 3.6e-19 68.9 0.8 7.3e-19 67.9 0.8 1.6 1 0 0 1 1 1 1 Chorismate mutase type II NeuB PF03102.14 EMT52126.1 - 1.7e-05 24.4 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 NeuB family Bclx_interact PF08945.10 EMT52126.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain DUF3951 PF13131.6 EMT52127.1 - 2.1e-12 47.0 0.1 2.4e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3951) Trns_repr_metal PF02583.17 EMT52128.1 - 3e-29 101.2 2.4 4e-29 100.8 2.4 1.2 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor V-ATPase_H_C PF11698.8 EMT52128.1 - 0.0028 17.7 0.3 0.0032 17.6 0.3 1.1 1 0 0 1 1 1 1 V-ATPase subunit H Peripla_BP_3 PF13377.6 EMT52129.1 - 1.1e-37 129.9 0.1 2.8e-37 128.6 0.1 1.6 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EMT52129.1 - 3.9e-34 118.4 0.1 4.6e-34 118.1 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 EMT52129.1 - 2.1e-22 80.0 0.0 2.7e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 EMT52129.1 - 3.2e-11 42.8 0.1 9.1e-11 41.4 0.1 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family PNP_UDP_1 PF01048.20 EMT52130.1 - 1.1e-54 185.2 0.7 1.4e-54 184.9 0.7 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Glutaredoxin PF00462.24 EMT52130.1 - 3.8e-11 43.0 0.1 8.2e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 EMT52130.1 - 0.0011 18.9 0.1 0.0038 17.3 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin domain DUF2464 PF10240.9 EMT52130.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Multivesicular body subunit 12 Hist_deacetyl PF00850.19 EMT52131.1 - 5.9e-80 269.0 0.0 6.9e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain CBS PF00571.28 EMT52132.1 - 1.6e-31 108.5 1.6 3.8e-17 62.5 0.1 2.7 3 0 0 3 3 3 2 CBS domain ACT PF01842.25 EMT52132.1 - 6.9e-09 35.3 0.0 1.7e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 EMT52132.1 - 0.00062 20.3 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 ACT domain MreC PF04085.14 EMT52132.1 - 0.019 14.8 0.1 0.11 12.4 0.2 1.9 2 0 0 2 2 2 0 rod shape-determining protein MreC DUF727 PF05303.12 EMT52132.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF727) Acetyltransf_1 PF00583.25 EMT52133.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Transgly PF00912.22 EMT52134.1 - 5.4e-57 192.1 0.1 8.2e-57 191.5 0.1 1.3 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 EMT52134.1 - 7.1e-33 114.1 0.3 1.3e-32 113.2 0.3 1.4 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain RGI_lyase PF18370.1 EMT52134.1 - 5.1e-06 26.7 2.6 0.032 14.5 0.8 3.0 2 0 0 2 2 2 2 Rhamnogalacturonan I lyases beta-sheet domain Tissue_fac PF01108.17 EMT52134.1 - 0.0043 16.9 0.1 0.28 11.0 0.1 2.6 2 0 0 2 2 2 1 Tissue factor Chitin_synth_1N PF08407.11 EMT52134.1 - 0.066 13.2 0.1 8 6.5 0.0 2.6 2 0 0 2 2 2 0 Chitin synthase N-terminal tRNA-synt_1b PF00579.25 EMT52136.1 - 4.5e-77 259.3 0.1 6.4e-77 258.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 EMT52136.1 - 2.3e-08 33.6 0.1 5.2e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 S4 domain Unstab_antitox PF09720.10 EMT52136.1 - 0.011 15.8 1.1 0.017 15.2 0.2 1.9 2 0 0 2 2 2 0 Putative addiction module component TyrRSs_C PF16714.5 EMT52136.1 - 0.028 14.2 0.0 0.087 12.6 0.0 1.8 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain S4_2 PF13275.6 EMT52136.1 - 0.13 12.1 0.7 0.36 10.7 0.7 1.8 1 0 0 1 1 1 0 S4 domain DinB_2 PF12867.7 EMT52137.1 - 3.1e-19 69.8 0.6 3.7e-19 69.5 0.6 1.0 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 EMT52137.1 - 0.00017 21.6 0.3 0.0002 21.3 0.3 1.1 1 0 0 1 1 1 1 DinB family DUF664 PF04978.12 EMT52137.1 - 0.00074 20.0 0.4 0.001 19.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF664) MDMPI_N PF11716.8 EMT52137.1 - 0.0012 19.6 0.1 0.0017 19.0 0.1 1.3 1 1 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain Ribosomal_S4 PF00163.19 EMT52138.1 - 2.1e-30 105.5 1.2 3.4e-30 104.8 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EMT52138.1 - 6.7e-23 80.2 0.0 1.1e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EMT52138.1 - 0.04 13.7 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 S4 domain Ub-Mut7C PF14451.6 EMT52138.1 - 0.048 13.5 0.2 0.13 12.1 0.0 1.8 2 1 0 2 2 2 0 Mut7-C ubiquitin E1-E2_ATPase PF00122.20 EMT52138.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 E1-E2 ATPase SLH PF00395.20 EMT52139.1 - 1.6e-15 56.8 0.0 2.5e-06 27.4 0.0 3.6 3 0 0 3 3 3 3 S-layer homology domain PepSY PF03413.19 EMT52139.1 - 3.5e-06 27.5 9.5 0.78 10.3 0.1 6.7 6 1 0 6 6 6 3 Peptidase propeptide and YPEB domain DUF4901 PF16244.5 EMT52139.1 - 0.0012 18.2 0.0 0.0042 16.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4901) YPEB PF14620.6 EMT52139.1 - 0.0015 18.0 0.2 0.031 13.6 0.1 2.3 2 0 0 2 2 2 1 YpeB sporulation His_Phos_1 PF00300.22 EMT52140.1 - 7.2e-57 192.2 2.2 8.9e-57 191.9 2.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HTH_23 PF13384.6 EMT52140.1 - 0.066 13.0 0.7 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain CE2_N PF17996.1 EMT52140.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal GGDEF PF00990.21 EMT52141.1 - 7.7e-41 139.5 0.0 2.1e-40 138.1 0.0 1.8 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GAF_2 PF13185.6 EMT52141.1 - 2.7e-22 79.6 0.0 1e-09 38.8 0.0 4.8 4 0 0 4 4 4 3 GAF domain GAF_3 PF13492.6 EMT52141.1 - 3e-18 66.4 0.1 4.7e-11 43.2 0.0 3.8 4 0 0 4 4 4 3 GAF domain GAF PF01590.26 EMT52141.1 - 4.4e-18 66.2 0.0 3.1e-09 37.6 0.0 3.6 3 0 0 3 3 3 3 GAF domain DUF3369 PF11849.8 EMT52141.1 - 0.0024 18.1 0.6 0.99 9.6 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3369) Trans_reg_C PF00486.28 EMT52141.1 - 0.01 15.9 0.2 1.4 9.0 0.1 3.3 3 1 0 3 3 3 0 Transcriptional regulatory protein, C terminal Lactamase_B PF00753.27 EMT52142.1 - 4.3e-25 88.9 0.1 5.7e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMT52142.1 - 0.00021 20.9 0.1 0.0004 19.9 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Adhesin_Dr PF04619.12 EMT52143.1 - 0.064 13.2 0.2 10 6.1 0.1 2.6 2 0 0 2 2 2 0 Dr-family adhesin TIMELESS PF04821.14 EMT52143.1 - 0.086 12.1 0.1 0.17 11.1 0.1 1.3 1 1 0 1 1 1 0 Timeless protein TetR_N PF00440.23 EMT52144.1 - 1.5e-15 56.7 0.7 1.5e-15 56.7 0.7 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 EMT52144.1 - 1.2e-07 31.8 0.1 2.2e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 EMT52144.1 - 4e-05 23.8 0.1 7.7e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_27 PF17935.1 EMT52144.1 - 0.0013 18.7 0.2 0.0036 17.3 0.0 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_5 PF01022.20 EMT52144.1 - 0.0058 16.5 0.1 0.046 13.6 0.0 2.5 2 1 0 2 2 2 1 Bacterial regulatory protein, arsR family DUF5377 PF17347.2 EMT52144.1 - 0.045 14.1 0.3 6.2 7.3 0.0 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5377) Oest_recep PF02159.15 EMT52144.1 - 0.1 13.1 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 Oestrogen receptor EzrA PF06160.12 EMT52145.1 - 3.1e-54 184.1 32.2 3.1e-32 111.5 8.4 2.8 3 0 0 3 3 3 2 Septation ring formation regulator, EzrA TPM_phosphatase PF04536.14 EMT52145.1 - 1.8e-07 31.4 1.4 1.4e-06 28.4 0.2 2.8 2 0 0 2 2 2 1 TPM domain DUF1771 PF08590.10 EMT52145.1 - 0.11 12.9 1.4 0.55 10.7 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) DUF1664 PF07889.12 EMT52145.1 - 0.15 12.1 4.5 0.6 10.2 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Lipase_GDSL PF00657.22 EMT52145.1 - 0.18 11.7 0.1 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase Sec34 PF04136.15 EMT52145.1 - 0.58 10.0 4.8 12 5.7 0.4 3.5 2 1 1 3 3 3 0 Sec34-like family DUF948 PF06103.11 EMT52145.1 - 0.93 9.8 5.9 2.7 8.3 0.1 4.4 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF3185 PF11381.8 EMT52146.1 - 2 8.5 6.6 88 3.2 7.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) HI0933_like PF03486.14 EMT52147.1 - 5.3e-144 479.9 0.0 6e-144 479.7 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EMT52147.1 - 1.6e-16 60.4 0.9 5.9e-11 42.1 0.1 3.1 2 1 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 EMT52147.1 - 8.4e-14 51.5 0.4 9.5e-07 28.3 0.1 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMT52147.1 - 2e-11 43.6 5.5 1.4e-07 31.0 1.7 2.8 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EMT52147.1 - 3.4e-11 43.1 0.0 4.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EMT52147.1 - 5.7e-08 32.7 3.2 0.0011 18.6 1.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMT52147.1 - 9.9e-07 29.2 2.3 0.034 14.7 0.2 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMT52147.1 - 1.3e-06 27.8 0.5 0.0015 17.7 0.3 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 EMT52147.1 - 2.5e-06 27.0 1.0 5.1e-06 26.0 1.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMT52147.1 - 8.1e-06 25.3 1.2 0.0012 18.2 0.9 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMT52147.1 - 0.00014 21.3 0.7 0.0013 18.1 0.0 2.3 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMT52147.1 - 0.00044 20.4 2.7 0.00061 20.0 1.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMT52147.1 - 0.0012 18.2 1.9 0.046 13.0 0.9 2.5 1 1 1 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 EMT52147.1 - 0.0048 15.8 0.5 0.13 11.1 0.2 2.2 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 EMT52147.1 - 0.017 15.1 0.7 6.8 6.7 0.2 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EMT52147.1 - 0.034 13.4 0.1 0.089 12.1 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Acetyltransf_1 PF00583.25 EMT52148.1 - 0.0002 21.5 0.0 0.00039 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 EMT52148.1 - 0.0026 17.9 0.1 0.0092 16.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT52148.1 - 0.02 14.9 0.0 0.055 13.4 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf_Rg PF17915.1 EMT52148.1 - 0.026 13.9 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Reverse gyrase zinc finger Acetyltransf_7 PF13508.7 EMT52148.1 - 0.074 13.5 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M42 PF05343.14 EMT52149.1 - 1.1e-104 349.5 0.0 1.3e-104 349.3 0.0 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 EMT52149.1 - 3.9e-08 33.2 0.1 1.2e-07 31.6 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1294 PF06961.13 EMT52149.1 - 0.18 12.1 0.1 0.37 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) sCache_2 PF17200.4 EMT52151.1 - 7.5e-28 97.3 0.0 1.6e-27 96.2 0.0 1.5 2 0 0 2 2 2 1 Single Cache domain 2 HD PF01966.22 EMT52151.1 - 1.5e-20 73.6 0.5 3.2e-20 72.6 0.2 1.8 2 0 0 2 2 2 1 HD domain HD_5 PF13487.6 EMT52151.1 - 2.1e-16 59.9 0.3 5.7e-16 58.5 0.3 1.8 1 0 0 1 1 1 1 HD domain dCache_2 PF08269.11 EMT52151.1 - 7.3e-16 58.2 0.0 1.8e-14 53.7 0.0 2.1 1 1 0 1 1 1 1 Cache domain Cache_3-Cache_2 PF17201.4 EMT52151.1 - 1.9e-15 56.9 0.0 7.3e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 Cache 3/Cache 2 fusion domain HDOD PF08668.12 EMT52151.1 - 5.5e-06 26.0 0.0 9.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 HDOD domain AphA_like PF14557.6 EMT52151.1 - 0.0057 16.4 0.0 0.0099 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator MFS_1 PF07690.16 EMT52153.1 - 6.1e-37 127.4 47.9 1.1e-26 93.6 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT52153.1 - 4.4e-08 32.4 10.1 4.4e-08 32.4 10.1 2.8 2 2 1 3 3 3 1 Sugar (and other) transporter Spore_YtrH PF14034.6 EMT52154.1 - 1.2e-36 124.9 3.5 1.3e-36 124.8 3.5 1.0 1 0 0 1 1 1 1 Sporulation protein YtrH Nairo_nucleo PF02477.15 EMT52155.1 - 0.03 13.2 0.3 0.048 12.5 0.2 1.3 1 1 0 1 1 1 0 Nucleocapsid N protein MACPF PF01823.19 EMT52155.1 - 0.093 12.8 0.2 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 MAC/Perforin domain DUF5101 PF17031.5 EMT52155.1 - 0.51 10.5 8.0 0.62 10.2 7.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5101) Spo0M PF07070.11 EMT52156.1 - 1.4e-81 273.0 0.0 1.7e-81 272.8 0.0 1.0 1 0 0 1 1 1 1 SpoOM protein Arrestin_C PF02752.22 EMT52156.1 - 0.022 15.2 0.0 0.03 14.8 0.0 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain SHMT PF00464.19 EMT52158.1 - 9.8e-178 590.8 0.1 1.1e-177 590.6 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EMT52158.1 - 5e-11 42.4 0.0 7.5e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EMT52158.1 - 1.3e-09 37.7 0.1 2e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EMT52158.1 - 5.5e-07 29.2 0.3 9.4e-07 28.5 0.2 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EMT52158.1 - 0.00027 19.6 0.0 0.00042 19.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMT52158.1 - 0.00031 19.8 0.0 0.00058 18.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V PhoU_div PF01865.16 EMT52158.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 CodY PF06018.14 EMT52159.1 - 1.9e-43 148.0 0.0 2.4e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 CodY GAF-like domain HTH_CodY PF08222.11 EMT52159.1 - 2e-32 110.5 0.1 4.5e-32 109.4 0.1 1.6 1 0 0 1 1 1 1 CodY helix-turn-helix domain HTH_11 PF08279.12 EMT52159.1 - 0.00021 21.1 0.2 0.00048 20.0 0.2 1.5 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 EMT52159.1 - 0.00046 19.8 0.7 0.0014 18.2 0.5 2.0 1 1 1 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 EMT52159.1 - 0.0014 18.5 0.1 0.0034 17.3 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 EMT52159.1 - 0.0019 18.0 0.2 0.0037 17.1 0.2 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 EMT52159.1 - 0.0039 17.2 0.2 0.0069 16.4 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 EMT52159.1 - 0.0055 16.5 0.2 0.011 15.5 0.2 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.22 EMT52159.1 - 0.016 15.2 0.1 0.034 14.1 0.1 1.6 1 1 0 1 1 1 0 MarR family Rrf2 PF02082.20 EMT52159.1 - 0.02 15.2 0.4 0.056 13.8 0.3 1.7 1 1 0 1 1 1 0 Transcriptional regulator HTH_5 PF01022.20 EMT52159.1 - 0.021 14.7 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TrmB PF01978.19 EMT52159.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EMT52159.1 - 0.13 11.8 0.2 0.24 11.0 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.16 EMT52161.1 - 3.1e-33 115.2 45.6 3.1e-33 115.2 45.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 EMT52161.1 - 9.1e-20 70.5 19.6 1.2e-19 70.1 19.6 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 EMT52161.1 - 8.9e-05 21.2 6.0 8.9e-05 21.2 6.0 2.7 1 1 2 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 EMT52161.1 - 0.00091 18.2 13.5 0.00091 18.2 13.5 2.1 2 0 0 2 2 2 2 MFS_1 like family DUF3681 PF12442.8 EMT52161.1 - 0.35 11.4 5.7 0.36 11.3 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3681) HTH_20 PF12840.7 EMT52162.1 - 8.3e-13 48.2 1.1 1.4e-12 47.5 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 EMT52162.1 - 5e-09 35.9 0.3 1.3e-08 34.5 0.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 EMT52162.1 - 3.3e-06 26.8 0.1 6.5e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 EMT52162.1 - 4.6e-06 26.1 0.0 1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EMT52162.1 - 1.6e-05 24.7 0.2 0.00014 21.6 0.0 2.4 2 0 0 2 2 2 1 MarR family HTH_micro PF17007.5 EMT52162.1 - 4.2e-05 22.6 0.2 5.8e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 HTH-like MarR PF01047.22 EMT52162.1 - 0.00011 22.0 0.0 0.00033 20.5 0.0 1.8 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 EMT52162.1 - 0.0006 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 EMT52162.1 - 0.0035 17.2 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 HTH domain LexA_DNA_bind PF01726.16 EMT52162.1 - 0.0038 17.0 0.0 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 LexA DNA binding domain HTS PF04204.16 EMT52162.1 - 0.0049 15.9 0.1 0.0065 15.4 0.1 1.2 1 0 0 1 1 1 1 Homoserine O-succinyltransferase HTH_10 PF04967.12 EMT52162.1 - 0.0067 16.2 0.7 0.13 12.1 0.0 2.7 3 0 0 3 3 3 1 HTH DNA binding domain HTH_34 PF13601.6 EMT52162.1 - 0.0083 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain B-block_TFIIIC PF04182.12 EMT52162.1 - 0.017 15.2 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC TFIIE_alpha PF02002.17 EMT52162.1 - 0.023 14.6 0.8 0.07 13.0 0.1 2.1 2 1 1 3 3 3 0 TFIIE alpha subunit DUF2513 PF10711.9 EMT52162.1 - 0.063 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_Crp_2 PF13545.6 EMT52162.1 - 0.07 13.1 0.1 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 EMT52162.1 - 0.082 13.3 0.1 0.21 12.0 0.1 1.7 2 0 0 2 2 1 0 Transcriptional regulator HTH_40 PF14493.6 EMT52162.1 - 0.099 13.1 0.8 0.31 11.5 0.2 2.2 2 1 1 3 3 2 0 Helix-turn-helix domain HTH_28 PF13518.6 EMT52162.1 - 0.16 12.1 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MFS_3 PF05977.13 EMT52163.1 - 1.6e-23 82.9 23.0 2.1e-23 82.5 23.0 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 EMT52163.1 - 8.1e-21 74.3 64.0 1e-19 70.7 35.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMT52163.1 - 9.7e-05 21.1 12.4 9.7e-05 21.1 12.4 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 EMT52164.1 - 7.2e-27 94.2 39.6 7.2e-27 94.2 39.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT52164.1 - 1.5e-25 89.6 29.5 2e-25 89.2 29.5 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 EMT52164.1 - 1.1e-07 30.8 24.6 1.2e-06 27.4 6.3 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EMT52164.1 - 0.00031 19.7 18.5 0.0035 16.2 10.6 2.1 2 0 0 2 2 2 2 MFS_1 like family adh_short PF00106.25 EMT52165.1 - 6.7e-53 179.1 0.0 8.3e-53 178.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMT52165.1 - 1.4e-36 126.3 0.0 1.7e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMT52165.1 - 3e-13 50.1 0.2 3.6e-13 49.8 0.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMT52165.1 - 3.5e-05 23.1 0.0 0.0029 16.8 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMT52165.1 - 0.00018 21.0 0.0 0.00031 20.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMT52165.1 - 0.0033 17.4 0.1 0.0053 16.7 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EMT52165.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 EMT52165.1 - 0.014 14.6 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EMT52165.1 - 0.033 13.6 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EMT52165.1 - 0.17 11.5 1.5 0.4 10.2 1.4 2.0 1 1 0 1 1 1 0 NmrA-like family DUF1540 PF07561.11 EMT52166.1 - 5e-17 61.9 6.7 6.4e-17 61.6 6.7 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1540) NT5C PF06941.12 EMT52167.1 - 4.7e-08 33.1 0.1 5.7e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Ala_racemase_N PF01168.20 EMT52167.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain DUF5353 PF17304.2 EMT52168.1 - 0.0018 18.0 2.8 0.0021 17.8 1.9 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF5353) DUF4267 PF14087.6 EMT52168.1 - 0.011 15.9 0.4 0.021 14.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) Phage_holin_3_6 PF07332.11 EMT52168.1 - 0.015 15.3 0.8 0.025 14.6 0.8 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Phage_holin_2_3 PF16080.5 EMT52168.1 - 0.028 14.2 1.2 0.045 13.5 1.2 1.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 DUF4190 PF13828.6 EMT52168.1 - 0.2 11.4 6.7 4.2 7.2 7.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4190) MerC PF03203.14 EMT52168.1 - 0.48 10.9 2.5 0.77 10.2 2.5 1.3 1 0 0 1 1 1 0 MerC mercury resistance protein DUF4538 PF15061.6 EMT52168.1 - 1.3 8.8 3.3 27 4.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) NTPase_I-T PF01931.18 EMT52169.1 - 2.9e-39 134.5 0.0 3.3e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 MetJ PF01340.20 EMT52169.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Met Apo-repressor, MetJ DAP_epimerase PF01678.19 EMT52170.1 - 1.6e-67 225.2 0.2 3e-33 114.5 0.1 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase LysM PF01476.20 EMT52171.1 - 1.1e-59 198.2 7.0 1.5e-15 57.0 0.3 4.2 4 0 0 4 4 4 4 LysM domain Sigma70_r4 PF04545.16 EMT52171.1 - 0.061 12.9 0.0 0.4 10.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 TMF_TATA_bd PF12325.8 EMT52172.1 - 0.0048 17.1 1.3 0.0048 17.1 1.3 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding FapA PF03961.13 EMT52172.1 - 0.0073 15.0 1.1 0.0075 14.9 1.1 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A FlxA PF14282.6 EMT52172.1 - 0.011 15.8 0.6 0.011 15.7 0.6 1.0 1 0 0 1 1 1 0 FlxA-like protein DUF612 PF04747.12 EMT52172.1 - 0.017 14.3 2.5 0.018 14.2 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Strep_SA_rep PF06696.11 EMT52172.1 - 0.018 15.0 1.2 0.04 13.9 1.2 1.7 1 1 0 1 1 1 0 Streptococcal surface antigen repeat OmpH PF03938.14 EMT52172.1 - 0.025 14.9 3.2 0.025 14.9 3.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3496 PF12001.8 EMT52172.1 - 0.027 14.8 2.2 0.029 14.8 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) ABC_tran_CTD PF16326.5 EMT52172.1 - 0.06 13.6 3.4 0.072 13.4 3.4 1.2 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF1192 PF06698.11 EMT52172.1 - 0.064 13.3 1.9 0.076 13.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3251 PF11622.8 EMT52172.1 - 0.074 12.7 1.0 0.073 12.7 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Spc24 PF08286.11 EMT52172.1 - 0.093 13.0 1.4 0.093 13.0 1.4 1.0 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 NuA4 PF09340.10 EMT52172.1 - 0.72 9.8 2.8 2.3 8.2 2.8 1.7 1 1 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Aminotran_5 PF00266.19 EMT52173.1 - 1.8e-81 274.0 0.0 2.1e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMT52173.1 - 0.00016 21.0 0.0 0.018 14.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EMT52173.1 - 0.019 14.3 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.21 EMT52173.1 - 0.079 11.6 0.0 0.19 10.3 0.0 1.6 1 0 0 1 1 1 0 Aminotransferase class-III T2SSF PF00482.23 EMT52173.1 - 0.19 11.7 0.5 7.9 6.5 0.1 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F ThiI PF02568.14 EMT52174.1 - 3.2e-68 229.2 0.0 4.4e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) THUMP PF02926.17 EMT52174.1 - 5.2e-22 78.5 0.4 1.6e-21 76.9 0.4 1.8 2 0 0 2 2 2 1 THUMP domain QueC PF06508.13 EMT52174.1 - 9e-06 25.3 0.0 0.0058 16.1 0.0 2.2 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 EMT52174.1 - 0.002 17.9 0.0 0.027 14.2 0.0 2.3 1 1 0 1 1 1 1 PP-loop family NAD_synthase PF02540.17 EMT52174.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.16 EMT52174.1 - 0.06 12.1 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase FAA_hydrolase PF01557.18 EMT52175.1 - 5.4e-67 225.7 0.0 6.4e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 EMT52175.1 - 3e-09 37.6 0.0 1e-08 35.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2437) DctM PF06808.12 EMT52177.1 - 3.7e-101 339.0 42.8 3.7e-101 339.0 42.8 1.6 1 1 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component DUF3394 PF11874.8 EMT52177.1 - 0.027 14.1 8.2 0.067 12.9 8.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Tmemb_cc2 PF10267.9 EMT52177.1 - 0.034 13.3 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF4884 PF16225.5 EMT52177.1 - 0.17 11.9 0.6 0.36 10.9 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4884) Alba PF01918.21 EMT52177.1 - 0.19 11.6 0.1 0.37 10.7 0.1 1.4 1 0 0 1 1 1 0 Alba DUF1850 PF08905.11 EMT52178.1 - 9.4e-16 57.9 0.2 1.3e-15 57.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1850) NMT1_3 PF16868.5 EMT52179.1 - 6.4e-96 321.2 3.2 7.4e-96 321.0 3.2 1.0 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 EMT52179.1 - 1.6e-10 41.0 1.2 2.5e-10 40.4 1.2 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EMT52179.1 - 2.2e-10 40.9 0.5 4.7e-10 39.8 0.5 1.6 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 EMT52179.1 - 8.1e-09 35.2 1.2 5.2e-07 29.3 1.1 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 EMT52179.1 - 0.00045 20.0 0.3 0.00045 20.0 0.3 1.5 2 0 0 2 2 2 1 NMT1-like family DUF3578 PF12102.8 EMT52179.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3578) Sigma54_activat PF00158.26 EMT52180.1 - 1.2e-70 236.6 0.1 1.9e-70 236.0 0.1 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 EMT52180.1 - 1.6e-24 86.2 0.1 3.5e-24 85.1 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 EMT52180.1 - 1.1e-23 83.9 0.0 5.2e-23 81.7 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 EMT52180.1 - 1.2e-12 47.4 3.3 1.7e-12 46.9 0.8 2.5 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 EMT52180.1 - 2.3e-06 27.7 0.0 5.8e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EMT52180.1 - 4.7e-05 23.8 0.0 0.00017 22.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT52180.1 - 0.00053 20.4 0.6 0.00095 19.6 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EMT52180.1 - 0.0019 18.0 0.1 0.0049 16.6 0.1 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EMT52180.1 - 0.0023 18.1 0.0 0.0068 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EMT52180.1 - 0.0043 16.5 0.1 0.25 10.7 0.1 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EMT52180.1 - 0.011 15.0 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain HTH_23 PF13384.6 EMT52180.1 - 0.014 15.2 0.1 0.027 14.3 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain AAA_3 PF07726.11 EMT52180.1 - 0.039 13.8 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HTH_30 PF13556.6 EMT52180.1 - 0.056 13.3 0.7 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Met_gamma_lyase PF06838.11 EMT52180.1 - 0.067 11.7 0.1 0.096 11.2 0.1 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase HTH_50 PF18024.1 EMT52180.1 - 0.068 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_7 PF12775.7 EMT52180.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SBP_bac_3 PF00497.20 EMT52181.1 - 3e-52 177.3 0.0 4.2e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 HATPase_c PF02518.26 EMT52181.1 - 4e-24 85.3 0.1 1.8e-23 83.1 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT52181.1 - 2.5e-16 59.4 0.1 8.4e-16 57.8 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 EMT52181.1 - 0.00011 22.0 0.0 0.00059 19.7 0.0 2.0 2 0 0 2 2 2 1 GHKL domain PAS PF00989.25 EMT52181.1 - 0.00012 22.1 0.0 0.00035 20.5 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EMT52181.1 - 0.00032 20.9 0.0 0.00095 19.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 EMT52181.1 - 0.00085 19.3 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EMT52181.1 - 0.0034 17.2 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Big_3_3 PF13750.6 EMT52181.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) P53_tetramer PF07710.11 EMT52181.1 - 0.097 12.0 0.2 0.43 9.9 0.0 2.1 2 0 0 2 2 2 0 P53 tetramerisation motif Lig_chan-Glu_bd PF10613.9 EMT52181.1 - 0.13 12.5 0.1 0.74 10.0 0.1 2.2 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site DUF1097 PF06496.11 EMT52182.1 - 0.19 11.8 4.7 1.3 9.2 4.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1097) Ribonuc_L-PSP PF01042.21 EMT52183.1 - 3e-19 69.2 0.0 3.5e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PRA-CH PF01502.18 EMT52184.1 - 7.7e-34 115.4 0.2 1.2e-33 114.7 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EMT52184.1 - 2.5e-19 69.5 1.2 4.3e-19 68.7 1.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 EMT52184.1 - 3.7e-05 23.8 0.4 6.7e-05 23.0 0.4 1.4 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain His_biosynth PF00977.21 EMT52185.1 - 3.2e-87 291.8 1.6 3.7e-87 291.6 1.6 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 EMT52185.1 - 8.8e-09 35.2 1.8 7e-05 22.4 0.4 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase TMP-TENI PF02581.17 EMT52185.1 - 6.8e-06 25.5 0.4 0.016 14.5 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase DHO_dh PF01180.21 EMT52185.1 - 7.9e-05 22.0 0.1 0.23 10.6 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 EMT52185.1 - 0.0001 21.8 0.4 0.0035 16.8 0.1 2.2 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 EMT52185.1 - 0.00017 20.8 0.1 0.0038 16.4 0.0 2.1 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 EMT52185.1 - 0.0011 18.3 0.5 0.15 11.3 0.1 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EMT52185.1 - 0.0015 17.6 1.7 0.21 10.5 0.1 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain SBP_bac_3 PF00497.20 EMT52185.1 - 0.026 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Diphthami_syn_2 PF01902.17 EMT52185.1 - 0.069 12.7 0.0 0.23 10.9 0.0 1.8 1 1 0 1 1 1 0 Diphthamide synthase PcrB PF01884.17 EMT52185.1 - 0.075 12.5 0.2 0.61 9.5 0.0 2.0 2 0 0 2 2 2 0 PcrB family His_biosynth PF00977.21 EMT52186.1 - 8.7e-78 260.9 0.3 9.8e-78 260.7 0.3 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 EMT52186.1 - 0.0003 20.0 0.0 0.027 13.6 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 EMT52186.1 - 0.00052 19.5 3.0 0.0028 17.1 0.0 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.14 EMT52186.1 - 0.00069 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 EMT52186.1 - 0.0029 17.1 0.2 0.0067 15.9 0.1 1.6 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 EMT52186.1 - 0.0036 16.8 0.4 0.028 13.9 0.0 2.0 2 0 0 2 2 2 1 PcrB family Trp_syntA PF00290.20 EMT52186.1 - 0.0051 15.7 0.3 0.013 14.3 0.0 1.8 2 1 0 2 2 2 1 Tryptophan synthase alpha chain TMP-TENI PF02581.17 EMT52186.1 - 0.0062 15.9 0.4 0.034 13.5 0.1 2.1 2 0 0 2 2 2 1 Thiamine monophosphate synthase DHO_dh PF01180.21 EMT52186.1 - 0.0067 15.7 0.1 0.025 13.8 0.0 1.8 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase IMPDH PF00478.25 EMT52186.1 - 0.0077 15.3 0.4 0.28 10.1 0.0 2.6 1 1 2 3 3 3 1 IMP dehydrogenase / GMP reductase domain IGPS PF00218.21 EMT52186.1 - 0.03 13.5 0.1 2.7 7.1 0.0 2.8 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase BtpA PF03437.15 EMT52186.1 - 0.06 12.8 0.1 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 BtpA family GATase PF00117.28 EMT52187.1 - 1.4e-23 83.7 0.0 1.7e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EMT52187.1 - 3.2e-07 30.1 0.6 4.1e-07 29.8 0.1 1.4 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 EMT52187.1 - 1.3e-06 28.4 0.0 0.002 18.0 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 EMT52187.1 - 0.00012 21.9 2.3 0.00079 19.2 2.3 1.9 1 1 0 1 1 1 1 Peptidase C26 IGPD PF00475.18 EMT52188.1 - 1.4e-63 213.5 0.1 1.8e-63 213.2 0.1 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DS PF01916.17 EMT52188.1 - 0.041 13.1 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase Asp23 PF03780.13 EMT52188.1 - 0.054 13.9 0.0 0.16 12.4 0.0 1.7 2 0 0 2 2 2 0 Asp23 family, cell envelope-related function Histidinol_dh PF00815.20 EMT52189.1 - 5.8e-176 585.5 0.4 6.9e-176 585.2 0.4 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase DUF1340 PF07067.11 EMT52189.1 - 0.074 12.4 0.3 0.12 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) HisG PF01634.18 EMT52190.1 - 3.1e-53 180.0 0.1 2.1e-52 177.3 0.0 1.9 2 0 0 2 2 2 1 ATP phosphoribosyltransferase tRNA-synt_His PF13393.6 EMT52191.1 - 3.3e-86 289.4 0.6 3.9e-86 289.1 0.6 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2d PF01409.20 EMT52191.1 - 2e-05 24.2 0.0 3.5e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 EMT52191.1 - 4e-05 23.7 0.0 5.5e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EMT52191.1 - 0.0043 16.2 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Hexapep_2 PF14602.6 EMT52192.1 - 8.2e-15 54.3 5.7 9.7e-12 44.4 0.8 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EMT52192.1 - 9.8e-14 50.5 6.8 1.1e-09 37.6 1.3 2.7 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) ABC_export PF16962.5 EMT52192.1 - 0.012 14.1 1.7 0.016 13.7 1.7 1.1 1 0 0 1 1 1 0 Putative ABC exporter Hpr_kinase_C PF07475.12 EMT52193.1 - 3.1e-75 251.4 1.4 3.1e-75 251.4 1.4 1.6 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain Hpr_kinase_N PF02603.16 EMT52193.1 - 8.8e-39 132.4 0.0 1.5e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 HPr Serine kinase N terminus DRTGG PF07085.12 EMT52193.1 - 0.00037 20.3 0.0 0.00091 19.0 0.0 1.7 1 0 0 1 1 1 1 DRTGG domain PucR PF07905.11 EMT52193.1 - 0.0013 19.0 0.1 0.009 16.3 0.0 2.3 2 1 0 2 2 2 1 Purine catabolism regulatory protein-like family AAA_28 PF13521.6 EMT52193.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain HATPase_c_5 PF14501.6 EMT52194.1 - 2.5e-15 56.2 0.0 5.8e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c PF02518.26 EMT52194.1 - 4.3e-15 56.2 0.0 7.8e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPOB_a PF14689.6 EMT52194.1 - 2.2e-07 30.5 0.2 5.2e-07 29.3 0.2 1.6 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain KAR9 PF08580.10 EMT52194.1 - 0.19 10.2 0.1 0.26 9.8 0.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 PHO4 PF01384.20 EMT52194.1 - 0.24 10.4 4.8 0.31 10.0 4.8 1.3 1 0 0 1 1 1 0 Phosphate transporter family AgrB PF04647.15 EMT52195.1 - 2.6e-27 95.3 15.4 3.1e-27 95.1 15.4 1.0 1 0 0 1 1 1 1 Accessory gene regulator B DUF3810 PF12725.7 EMT52195.1 - 2.8 7.2 8.0 0.077 12.3 1.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Orf78 PF06024.12 EMT52195.1 - 9.2 6.6 7.2 3.8 7.9 1.9 2.3 2 1 0 2 2 2 0 Orf78 (ac78) Phage_holin_4_2 PF04020.13 EMT52197.1 - 1.5e-26 93.1 20.2 1.7e-26 92.9 20.2 1.0 1 0 0 1 1 1 1 Mycobacterial 4 TMS phage holin, superfamily IV DUF2070 PF09843.9 EMT52197.1 - 8.5 4.5 10.9 9.3 4.4 10.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HD PF01966.22 EMT52198.1 - 1.6e-16 60.7 0.6 2.5e-16 60.0 0.2 1.5 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 EMT52198.1 - 0.0046 16.5 0.0 0.01 15.4 0.0 1.5 1 1 0 1 1 1 1 HDOD domain DUF4202 PF13875.6 EMT52198.1 - 0.012 15.5 0.0 0.039 13.8 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4202) MIOX PF05153.15 EMT52198.1 - 0.043 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol oxygenase UvrA_inter PF17760.1 EMT52199.1 - 5.3e-43 145.5 2.7 5.3e-42 142.3 2.4 2.5 2 0 0 2 2 2 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 EMT52199.1 - 3.7e-38 130.3 0.0 5.2e-36 123.3 0.0 3.3 3 0 0 3 3 3 1 UvrA DNA-binding domain ABC_tran PF00005.27 EMT52199.1 - 9.7e-22 78.0 0.2 5e-11 43.3 0.1 4.4 3 1 0 3 3 3 3 ABC transporter SMC_N PF02463.19 EMT52199.1 - 9.5e-12 44.8 0.0 0.24 10.8 0.0 4.1 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMT52199.1 - 4.1e-09 37.0 0.1 0.0017 18.8 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 EMT52199.1 - 4.2e-08 33.3 1.2 0.0045 16.8 0.0 4.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT52199.1 - 1.9e-07 30.7 0.1 0.0076 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMT52199.1 - 9e-07 28.9 0.0 0.0088 16.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EMT52199.1 - 2.7e-06 27.7 0.0 0.017 15.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EMT52199.1 - 2.6e-05 24.4 0.0 0.72 10.0 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 EMT52199.1 - 8.5e-05 23.1 0.0 0.13 12.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 EMT52199.1 - 0.00011 22.1 0.1 0.57 10.1 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_23 PF13476.6 EMT52199.1 - 0.00012 22.7 1.1 2.3 8.7 0.2 3.5 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 EMT52199.1 - 0.00024 21.2 0.1 0.021 14.9 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 EMT52199.1 - 0.00044 19.9 2.9 0.068 12.7 0.0 3.3 3 1 0 3 3 2 1 AAA domain DnaJ_CXXCXGXG PF00684.19 EMT52199.1 - 0.00048 20.4 5.4 0.11 12.9 0.2 3.6 3 1 0 3 3 3 1 DnaJ central domain AAA_14 PF13173.6 EMT52199.1 - 0.00074 19.6 0.0 1.1 9.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain BCA_ABC_TP_C PF12399.8 EMT52199.1 - 0.00099 19.0 1.2 0.0046 16.8 0.1 2.5 2 0 0 2 2 2 1 Branched-chain amino acid ATP-binding cassette transporter cobW PF02492.19 EMT52199.1 - 0.0012 18.5 0.2 0.098 12.2 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 EMT52199.1 - 0.0012 18.7 0.0 0.0091 15.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EMT52199.1 - 0.0013 18.7 0.0 0.46 10.4 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EMT52199.1 - 0.0015 17.8 0.1 0.045 12.9 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 EMT52199.1 - 0.0016 18.4 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EMT52199.1 - 0.0026 17.5 0.2 1.7 8.3 0.0 3.7 4 0 0 4 4 4 1 AAA domain NTPase_1 PF03266.15 EMT52199.1 - 0.0046 16.9 3.1 0.44 10.4 0.0 3.9 3 1 1 4 4 4 1 NTPase AAA_15 PF13175.6 EMT52199.1 - 0.0048 16.6 0.1 0.87 9.2 0.0 3.6 3 1 1 4 4 4 1 AAA ATPase domain Sigma54_activat PF00158.26 EMT52199.1 - 0.018 14.8 0.1 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EMT52199.1 - 0.021 14.4 0.0 6.5 6.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region RACo_linker PF17650.1 EMT52199.1 - 0.021 14.7 0.4 2.2 8.2 0.0 3.3 3 0 0 3 3 3 0 RACo linker region T2SSE PF00437.20 EMT52199.1 - 0.021 13.9 0.1 0.93 8.5 0.0 2.9 2 0 0 2 2 2 0 Type II/IV secretion system protein MeaB PF03308.16 EMT52199.1 - 0.023 13.7 0.0 0.29 10.1 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 EMT52199.1 - 0.032 13.6 0.0 6.2 6.1 0.0 2.6 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 EMT52199.1 - 0.032 14.0 0.2 1.7 8.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain PRK PF00485.18 EMT52199.1 - 0.036 13.8 0.0 0.53 10.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.9 EMT52199.1 - 0.037 13.3 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EMT52199.1 - 0.043 14.2 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 EMT52199.1 - 0.054 12.8 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.23 EMT52199.1 - 0.068 13.2 0.0 0.068 13.2 0.0 2.1 2 0 0 2 2 1 0 Dynamin family SbcCD_C PF13558.6 EMT52199.1 - 0.11 12.8 0.0 36 4.7 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 EMT52199.1 - 0.12 11.7 0.1 17 4.6 0.0 2.8 3 0 0 3 3 2 0 Zeta toxin CbiA PF01656.23 EMT52199.1 - 0.14 12.2 0.0 58 3.7 0.0 3.8 4 1 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 EMT52199.1 - 0.15 12.3 0.0 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Anti-TRAP PF15777.5 EMT52199.1 - 0.16 12.0 6.7 22 5.1 0.2 3.7 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF463 PF04317.12 EMT52199.1 - 0.17 10.7 0.7 0.4 9.5 0.0 1.8 2 0 0 2 2 2 0 YcjX-like family, DUF463 IstB_IS21 PF01695.17 EMT52199.1 - 0.65 9.7 1.9 26 4.5 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF87 PF01935.17 EMT52199.1 - 0.97 9.5 3.8 0.54 10.3 0.1 2.5 2 0 0 2 2 1 0 Helicase HerA, central domain UvrB_inter PF17757.1 EMT52200.1 - 3.5e-35 120.1 1.3 1.1e-34 118.4 0.2 2.5 3 0 0 3 3 3 1 UvrB interaction domain UvrB PF12344.8 EMT52200.1 - 1.3e-23 82.5 3.6 2.7e-23 81.5 3.6 1.6 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 EMT52200.1 - 5.1e-19 68.7 1.9 2.4e-18 66.5 0.1 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMT52200.1 - 6.7e-12 45.7 0.1 8.7e-11 42.1 0.0 2.6 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit UVR PF02151.19 EMT52200.1 - 1.9e-08 33.8 8.5 1.9e-08 33.8 8.5 2.8 2 0 0 2 2 2 1 UvrB/uvrC motif AAA_30 PF13604.6 EMT52200.1 - 6.2e-05 22.8 0.1 0.0043 16.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EMT52200.1 - 0.00049 20.5 1.5 0.47 10.8 0.4 2.9 2 1 0 2 2 2 2 AAA domain DEAD PF00270.29 EMT52200.1 - 0.00075 19.3 0.1 0.033 14.0 0.0 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_7 PF12775.7 EMT52200.1 - 0.0069 15.9 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 EMT52200.1 - 0.0073 15.9 0.1 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 EMT52200.1 - 0.013 14.4 0.1 0.037 12.9 0.1 1.8 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Arg_repressor_C PF02863.18 EMT52200.1 - 0.047 13.6 0.2 0.15 11.9 0.2 1.9 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain AAA_22 PF13401.6 EMT52200.1 - 0.047 14.0 0.0 0.26 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EMT52200.1 - 0.064 13.2 0.0 0.21 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 EMT52200.1 - 0.16 11.5 10.7 1 8.8 0.2 2.8 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF87 PF01935.17 EMT52200.1 - 0.43 10.6 3.3 0.32 11.1 0.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_11 PF13086.6 EMT52200.1 - 2.5 7.8 9.2 0.75 9.5 0.2 3.5 3 1 1 4 4 4 0 AAA domain FlgD PF03963.14 EMT52201.1 - 2e-13 50.4 10.4 5.3e-13 49.1 10.4 1.8 1 0 0 1 1 1 1 Flagellar hook capping protein - N-terminal region FLgD_tudor PF13861.6 EMT52201.1 - 6.4e-09 35.9 2.0 0.0042 17.3 0.1 3.5 3 0 0 3 3 3 2 FlgD Tudor-like domain Sde2_N_Ubi PF13019.6 EMT52201.1 - 0.14 11.9 0.3 0.25 11.2 0.3 1.3 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain DUF2187 PF09953.9 EMT52201.1 - 0.81 9.7 4.4 1.2 9.2 0.5 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2187) PepSY PF03413.19 EMT52202.1 - 5.4e-07 30.1 0.0 0.091 13.3 0.0 4.3 4 0 0 4 4 4 3 Peptidase propeptide and YPEB domain DUF4901 PF16244.5 EMT52202.1 - 2.5e-05 23.8 0.0 0.00059 19.3 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4901) PDZ_6 PF17820.1 EMT52203.1 - 1.3e-11 44.2 0.0 5.5e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EMT52203.1 - 3.7e-08 33.6 0.0 7.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EMT52203.1 - 6e-07 29.7 0.1 5.7e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EMT52203.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Wza_C PF18412.1 EMT52203.1 - 0.23 11.3 4.7 0.99 9.2 0.3 2.4 2 0 0 2 2 2 0 Outer-membrane lipoprotein Wza C-terminal domain Peptidase_S41 PF03572.18 EMT52204.1 - 2.7e-47 160.4 0.2 5e-47 159.6 0.2 1.5 1 0 0 1 1 1 1 Peptidase family S41 PG_binding_1 PF01471.18 EMT52204.1 - 5.8e-17 61.6 0.2 1.3e-16 60.5 0.2 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PDZ_6 PF17820.1 EMT52204.1 - 3.8e-15 55.5 0.1 8e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EMT52204.1 - 6e-12 45.7 0.1 2.1e-11 44.0 0.1 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EMT52204.1 - 1.7e-11 44.3 0.1 3.8e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain DUF3394 PF11874.8 EMT52204.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Peptidase_M23 PF01551.22 EMT52205.1 - 1.6e-32 111.6 2.7 1.6e-32 111.6 2.7 2.0 2 0 0 2 2 2 1 Peptidase family M23 TMPIT PF07851.13 EMT52205.1 - 0.0013 18.0 6.0 0.0013 18.0 6.0 2.2 2 0 0 2 2 2 1 TMPIT-like protein APG6_N PF17675.1 EMT52205.1 - 0.0022 18.5 13.2 0.0022 18.5 13.2 2.2 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF3450 PF11932.8 EMT52205.1 - 0.01 15.2 12.4 0.01 15.2 12.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 EMT52205.1 - 0.041 12.7 36.8 0.036 13.0 14.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.9 EMT52205.1 - 0.046 12.7 30.1 0.15 11.0 9.2 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 UPF0242 PF06785.11 EMT52205.1 - 0.2 11.7 24.1 0.081 13.0 7.8 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus zf-C4H2 PF10146.9 EMT52205.1 - 0.36 11.1 14.5 0.99 9.7 0.1 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein GAS PF13851.6 EMT52205.1 - 1.6 8.1 37.6 0.14 11.4 16.6 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2547 PF10818.8 EMT52205.1 - 1.6 9.7 8.6 0.94 10.5 3.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2547) Sec34 PF04136.15 EMT52205.1 - 2 8.3 20.5 2.1 8.2 7.4 2.3 2 0 0 2 2 2 0 Sec34-like family CENP-F_leu_zip PF10473.9 EMT52205.1 - 5.7 7.0 34.7 3.5 7.6 13.7 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 EMT52205.1 - 6.1 5.8 30.2 2.2 7.3 4.6 2.6 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FtsX_ECD PF18075.1 EMT52206.1 - 3.3e-25 88.5 0.5 4.6e-25 88.1 0.5 1.2 1 0 0 1 1 1 1 FtsX extracellular domain FtsX PF02687.21 EMT52206.1 - 2.1e-06 28.1 8.2 2.1e-06 28.1 8.2 2.9 3 0 0 3 3 3 1 FtsX-like permease family DUF1297 PF06973.12 EMT52206.1 - 0.013 15.1 0.2 0.024 14.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1297) VMA21 PF09446.10 EMT52206.1 - 0.034 14.2 2.8 2 8.6 0.1 2.7 2 0 0 2 2 2 0 VMA21-like domain YqzM PF14141.6 EMT52206.1 - 0.048 13.7 1.5 0.15 12.1 1.5 1.9 1 0 0 1 1 1 0 YqzM-like protein PAP2_C PF14360.6 EMT52206.1 - 0.078 13.5 4.1 0.18 12.4 0.4 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF5518 PF17647.1 EMT52206.1 - 2.7 8.2 24.5 0.23 11.6 10.5 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5518) Ost4 PF10215.9 EMT52206.1 - 5.5 6.9 9.8 5.9 6.8 0.7 2.7 2 0 0 2 2 2 0 Oligosaccaryltransferase ABC_tran PF00005.27 EMT52207.1 - 1.7e-35 122.5 0.0 2.5e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT52207.1 - 1.1e-09 38.6 0.0 2.3e-06 27.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EMT52207.1 - 9.4e-06 25.8 0.2 0.0086 16.2 0.0 2.3 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.19 EMT52207.1 - 2.6e-05 23.8 0.1 0.02 14.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMT52207.1 - 8.1e-05 23.1 0.0 0.0001 22.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT52207.1 - 0.00034 20.9 0.0 0.00089 19.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT52207.1 - 0.0014 18.6 0.0 0.0037 17.2 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EMT52207.1 - 0.0024 17.6 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 EMT52207.1 - 0.0024 17.8 0.8 0.43 10.5 0.1 2.2 2 0 0 2 2 2 1 NTPase MMR_HSR1 PF01926.23 EMT52207.1 - 0.011 15.8 0.1 0.097 12.8 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EMT52207.1 - 0.012 15.4 0.1 0.022 14.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EMT52207.1 - 0.023 14.4 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EMT52207.1 - 0.028 14.2 0.1 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EMT52207.1 - 0.028 14.3 0.1 0.089 12.7 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EMT52207.1 - 0.034 13.3 0.5 0.38 9.9 0.5 2.1 1 1 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 EMT52207.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Spore_IV_A PF09547.10 EMT52207.1 - 0.048 12.6 0.1 0.083 11.8 0.1 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) RNA_helicase PF00910.22 EMT52207.1 - 0.054 13.9 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EMT52207.1 - 0.06 12.8 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EMT52207.1 - 0.067 13.7 0.0 0.58 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EMT52207.1 - 0.079 12.7 0.1 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 EMT52207.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Septin Rad17 PF03215.15 EMT52207.1 - 0.096 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 EMT52207.1 - 0.1 12.2 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain SH3_2 PF07653.17 EMT52207.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain ATP-synt_ab PF00006.25 EMT52207.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Fe-ADH PF00465.19 EMT52208.1 - 1.3e-103 346.6 0.0 1.5e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMT52208.1 - 4.2e-14 52.9 0.0 5.3e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF4179 PF13786.6 EMT52209.1 - 4.6e-13 49.4 0.1 1.4e-12 47.9 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) DUF5643 PF18705.1 EMT52209.1 - 2.7e-10 40.2 2.4 0.0026 17.7 0.0 3.8 2 1 1 3 3 3 3 Family of unknown function (DUF5643) TetR_C_3 PF08362.11 EMT52209.1 - 0.021 14.8 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 YcdC-like protein, C-terminal region Sigma70_r2 PF04542.14 EMT52210.1 - 4.2e-18 64.9 0.8 6.5e-18 64.3 0.8 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT52210.1 - 4.8e-15 55.0 0.0 1.1e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT52210.1 - 1.3e-09 37.4 0.2 3.5e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 UPF0122 PF04297.14 EMT52210.1 - 0.00019 21.6 0.1 0.0032 17.7 0.0 2.2 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_ECF PF07638.11 EMT52210.1 - 0.00038 20.4 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 ECF sigma factor Terminase_5 PF06056.12 EMT52210.1 - 0.0024 17.7 0.0 0.0055 16.6 0.0 1.8 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) PCI PF01399.27 EMT52210.1 - 0.0037 17.8 0.1 0.66 10.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain Phage_antitermQ PF06530.12 EMT52210.1 - 0.0048 16.8 0.1 0.0098 15.8 0.1 1.5 1 0 0 1 1 1 1 Phage antitermination protein Q DUF134 PF02001.16 EMT52210.1 - 0.01 16.3 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_Tnp_ISL3 PF13542.6 EMT52210.1 - 0.013 14.9 0.1 0.84 9.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.6 EMT52210.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_AsnC-type PF13404.6 EMT52210.1 - 0.022 14.6 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_40 PF14493.6 EMT52210.1 - 0.024 15.1 0.2 19 5.8 0.0 3.1 1 1 2 3 3 3 0 Helix-turn-helix domain GerE PF00196.19 EMT52210.1 - 0.039 13.5 0.0 0.12 11.9 0.0 1.8 1 1 1 2 2 2 0 Bacterial regulatory proteins, luxR family DUF746 PF05344.11 EMT52210.1 - 0.058 13.2 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) HTH_17 PF12728.7 EMT52210.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Lyase_1 PF00206.20 EMT52211.1 - 1.7e-77 260.9 0.0 5.1e-77 259.3 0.0 1.8 3 0 0 3 3 3 1 Lyase ASL_C2 PF14698.6 EMT52211.1 - 8.4e-25 87.3 0.1 2.2e-24 86.0 0.1 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Arginosuc_synth PF00764.19 EMT52212.1 - 4.7e-178 592.4 0.0 5.5e-178 592.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase tRNA_Me_trans PF03054.16 EMT52212.1 - 0.05 12.4 0.0 0.095 11.5 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase QueC PF06508.13 EMT52212.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC TipAS PF07739.13 EMT52213.1 - 7.6e-37 126.4 4.9 7.6e-37 126.4 4.9 1.8 2 0 0 2 2 2 1 TipAS antibiotic-recognition domain MerR_1 PF13411.6 EMT52213.1 - 7.2e-17 61.3 1.1 1.3e-16 60.4 0.3 1.8 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 EMT52213.1 - 4.3e-12 45.6 0.6 7.8e-12 44.8 0.6 1.5 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 EMT52213.1 - 3e-08 34.1 6.6 4.9e-07 30.2 1.5 2.7 3 0 0 3 3 3 2 MerR, DNA binding DUF3287 PF11690.8 EMT52213.1 - 0.45 10.2 3.1 0.52 10.1 1.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) CHASE3 PF05227.13 EMT52213.1 - 0.47 10.4 5.8 2.5 8.0 4.8 2.3 1 1 1 2 2 2 0 CHASE3 domain CEP209_CC5 PF16574.5 EMT52213.1 - 3 8.0 10.7 8.8 6.5 10.7 1.6 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 VanW PF04294.13 EMT52214.1 - 2.3e-38 130.8 0.0 3e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 VanW like protein HTH_50 PF18024.1 EMT52215.1 - 0.046 13.3 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain His_Phos_1 PF00300.22 EMT52216.1 - 1.3e-27 96.8 0.0 1.9e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HD PF01966.22 EMT52217.1 - 2e-22 79.7 0.2 3.4e-22 78.9 0.2 1.4 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 EMT52217.1 - 1.4e-17 63.6 0.3 2.9e-17 62.7 0.3 1.5 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 EMT52217.1 - 1.2e-06 28.1 0.0 2.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 HDOD domain HD_6 PF18019.1 EMT52217.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 HD domain DUF5317 PF17248.2 EMT52218.1 - 7.7e-32 110.4 6.2 9.6e-32 110.1 6.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5317) OTCace PF00185.24 EMT52219.1 - 4.2e-60 202.4 0.0 6.3e-60 201.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EMT52219.1 - 8.4e-52 175.1 0.0 1.3e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain YjeF_N PF03853.15 EMT52219.1 - 0.068 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus CPSase_L_D2 PF02786.17 EMT52220.1 - 4.5e-118 392.3 0.0 2.3e-80 269.0 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EMT52220.1 - 1.8e-37 128.4 0.0 3.3e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATPgrasp_Ter PF15632.6 EMT52220.1 - 2.3e-21 75.9 0.0 6.9e-12 45.2 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EMT52220.1 - 2.8e-16 60.0 0.0 5.8e-09 36.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp PF02222.22 EMT52220.1 - 1.5e-15 57.2 0.0 2.5e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 EMT52220.1 - 6.8e-11 42.3 0.0 2.8e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Dala_Dala_lig_C PF07478.13 EMT52220.1 - 9.3e-10 38.4 0.0 1.2e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 EMT52220.1 - 1.9e-06 28.0 0.2 3.2e-05 24.0 0.0 3.0 4 0 0 4 4 4 1 MGS-like domain ATP-grasp_5 PF13549.6 EMT52220.1 - 3.5e-06 26.6 0.1 0.062 12.8 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_4 PF13535.6 EMT52220.1 - 1.9e-05 24.3 0.0 0.0021 17.7 0.0 2.8 2 1 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 EMT52220.1 - 0.0055 16.3 0.0 0.88 9.1 0.0 3.3 4 1 0 4 4 4 1 RimK-like ATP-grasp domain CoA_binding_2 PF13380.6 EMT52220.1 - 0.065 13.7 0.7 8.9 6.8 0.0 3.4 2 1 0 2 2 2 0 CoA binding domain TrkA_N PF02254.18 EMT52220.1 - 0.069 13.4 0.8 0.38 11.0 0.2 2.5 2 0 0 2 2 2 0 TrkA-N domain GATase PF00117.28 EMT52221.1 - 9.4e-46 156.0 0.0 1.3e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EMT52221.1 - 4e-45 152.8 0.0 1.5e-44 150.9 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EMT52221.1 - 7.8e-09 35.6 0.1 3.2e-06 27.1 0.1 2.8 1 1 1 2 2 2 1 Peptidase C26 Aminotran_3 PF00202.21 EMT52222.1 - 3.1e-113 378.5 0.0 3.7e-113 378.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMT52222.1 - 1.2e-05 24.7 0.0 2.2e-05 23.8 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EMT52222.1 - 2.4e-05 23.8 0.0 0.00025 20.5 0.0 2.1 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EMT52222.1 - 0.0008 18.5 0.1 0.084 11.8 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class-V AA_kinase PF00696.28 EMT52223.1 - 4.1e-43 147.7 1.1 4.7e-43 147.5 1.1 1.0 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 EMT52224.1 - 1.8e-33 115.6 0.0 3.7e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 EMT52224.1 - 6.8e-23 81.7 0.0 9.2e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 EMT52224.1 - 0.0023 18.0 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 EMT52224.1 - 0.0051 17.6 0.0 0.01 16.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Cytochrome_CBB3 PF13442.6 EMT52225.1 - 2.2e-14 53.5 0.0 3.4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EMT52225.1 - 4.1e-09 37.4 2.3 5.6e-08 33.8 0.2 2.5 2 1 0 2 2 2 1 Cytochrome c Cytochrome-c551 PF10643.9 EMT52225.1 - 1.9e-06 27.6 0.2 8.4e-06 25.5 0.0 1.8 1 1 1 2 2 2 1 Photosystem P840 reaction-centre cytochrome c-551 Cytochrom_C550 PF14495.6 EMT52225.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain YCII PF03795.14 EMT52226.1 - 1.2e-14 54.5 0.1 1.4e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 YCII-related domain GDPD PF03009.17 EMT52227.1 - 2.1e-42 145.6 0.0 3.2e-42 145.1 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EAL PF00563.20 EMT52227.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 EAL domain NolB PF17398.2 EMT52227.1 - 0.096 13.1 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein NolB GDPD_2 PF13653.6 EMT52227.1 - 0.13 12.8 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family PCRF PF03462.18 EMT52228.1 - 6.1e-59 199.1 0.2 1.7e-58 197.7 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EMT52228.1 - 4.7e-43 145.8 0.8 7.8e-43 145.1 0.8 1.3 1 0 0 1 1 1 1 RF-1 domain MIR PF02815.19 EMT52228.1 - 0.029 14.2 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 MIR domain Lipoprotein_7 PF01540.16 EMT52228.1 - 0.42 9.8 2.7 0.3 10.3 0.9 1.5 2 0 0 2 2 2 0 Adhesin lipoprotein Peptidase_S8 PF00082.22 EMT52230.1 - 4.3e-52 177.2 0.5 6.2e-52 176.7 0.5 1.2 1 0 0 1 1 1 1 Subtilase family SecA_DEAD PF07517.14 EMT52231.1 - 1.8e-133 444.3 8.1 3e-133 443.6 8.1 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 EMT52231.1 - 3.9e-67 226.2 7.7 3.9e-67 226.2 7.7 1.9 2 0 0 2 2 2 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 EMT52231.1 - 1e-42 145.3 1.8 3e-42 143.8 1.8 1.9 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 EMT52231.1 - 3.9e-05 23.5 0.5 0.00019 21.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMT52231.1 - 3.9e-05 24.0 0.7 0.00016 22.0 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMT52231.1 - 0.059 13.4 0.0 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4497 PF14924.6 EMT52231.1 - 0.14 12.6 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) AAA_19 PF13245.6 EMT52231.1 - 0.17 12.2 5.6 0.12 12.7 0.3 3.0 1 1 1 3 3 3 0 AAA domain Ribosomal_S30AE PF02482.19 EMT52232.1 - 2e-30 105.4 0.6 3.6e-30 104.6 0.6 1.4 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Ribosom_S30AE_C PF16321.5 EMT52232.1 - 2.5e-29 100.8 0.6 4.6e-29 99.9 0.6 1.5 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus DUF3794 PF12673.7 EMT52232.1 - 0.081 13.2 0.1 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3794) HD PF01966.22 EMT52233.1 - 2.2e-19 69.8 1.7 4.5e-19 68.9 1.3 1.7 2 0 0 2 2 2 1 HD domain HD_5 PF13487.6 EMT52233.1 - 1e-12 48.1 0.5 2.4e-12 46.9 0.5 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 EMT52233.1 - 1.1e-05 25.0 0.8 3.6e-05 23.3 0.8 1.8 1 1 0 1 1 1 1 HDOD domain CSD PF00313.22 EMT52234.1 - 9e-33 111.9 1.3 9.6e-33 111.9 1.3 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EMT52234.1 - 0.0064 16.2 1.0 0.0088 15.7 1.0 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.23 EMT52234.1 - 0.015 15.6 0.1 0.016 15.6 0.1 1.1 1 0 0 1 1 1 0 S1 RNA binding domain BPD_transp_1 PF00528.22 EMT52235.1 - 3.5e-19 69.3 7.1 4e-19 69.1 7.1 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_3 PF00497.20 EMT52236.1 - 5e-68 228.9 2.7 5.8e-68 228.7 2.7 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EMT52236.1 - 2.6e-08 34.1 0.0 1.1e-06 28.9 0.0 2.4 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Phosphonate-bd PF12974.7 EMT52236.1 - 1.5e-06 28.0 0.0 3.3e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EMT52236.1 - 1e-05 25.6 0.7 2.4e-05 24.4 0.7 1.6 1 1 1 2 2 2 1 NMT1/THI5 like OpuAC PF04069.12 EMT52236.1 - 3.6e-05 23.5 3.2 0.0037 16.9 0.2 2.2 1 1 1 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system NMT1_3 PF16868.5 EMT52236.1 - 0.00023 20.7 0.0 0.00039 20.0 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family DctP PF03480.13 EMT52236.1 - 0.006 16.0 0.0 0.3 10.4 0.0 2.9 2 1 1 3 3 3 1 Bacterial extracellular solute-binding protein, family 7 OmpA PF00691.20 EMT52237.1 - 1.5e-21 76.5 0.1 3.7e-21 75.3 0.0 1.7 2 0 0 2 2 2 1 OmpA family MotB_plug PF13677.6 EMT52237.1 - 0.00011 21.7 0.1 0.00022 20.8 0.1 1.5 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB PMEI PF04043.15 EMT52237.1 - 0.093 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DUF4686 PF15742.5 EMT52237.1 - 0.1 11.7 11.5 0.2 10.8 11.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) MotA_ExbB PF01618.16 EMT52238.1 - 3.3e-18 65.6 0.0 5.5e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family HisKA_7TM PF16927.5 EMT52238.1 - 0.0036 17.4 0.4 0.098 12.7 0.0 2.1 2 0 0 2 2 2 1 N-terminal 7TM region of histidine kinase YjfB_motility PF14070.6 EMT52239.1 - 3.3e-05 23.9 16.2 0.00013 22.1 16.2 2.1 1 1 0 1 1 1 1 Putative motility protein ZNRF_3_ecto PF18212.1 EMT52239.1 - 0.017 15.1 0.1 0.018 15.0 0.1 1.1 1 0 0 1 1 1 0 ZNRF-3 Ectodomain Ribosomal_L10 PF00466.20 EMT52239.1 - 0.023 14.8 0.1 0.025 14.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L10 STAG PF08514.11 EMT52239.1 - 0.027 14.4 0.8 0.03 14.3 0.8 1.1 1 0 0 1 1 1 0 STAG domain Beta-lactamase PF00144.24 EMT52240.1 - 9.4e-67 225.6 0.0 1.3e-66 225.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EMT52240.1 - 3.5e-06 27.4 0.0 6.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) SBP_bac_5 PF00496.22 EMT52241.1 - 5.9e-82 275.6 12.7 8.3e-82 275.1 12.7 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF327 PF03885.13 EMT52242.1 - 4.4e-39 133.7 5.0 5.1e-39 133.5 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF327) Bac_export_2 PF01312.19 EMT52243.1 - 8e-16 58.2 0.1 9.1e-16 58.0 0.1 1.1 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family Flg_hook PF02120.16 EMT52244.1 - 8.7e-07 28.7 0.1 9.1e-06 25.5 0.0 2.9 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK I_LWEQ PF01608.17 EMT52244.1 - 0.26 11.5 8.4 0.23 11.7 2.6 2.8 2 0 0 2 2 2 0 I/LWEQ domain NPV_P10 PF05531.12 EMT52244.1 - 0.8 10.2 4.1 2.6 8.6 0.3 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EMT52244.1 - 3.1 7.9 9.8 6.7 6.8 0.4 4.4 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) DUF2920 PF11144.8 EMT52245.1 - 2.5e-20 73.0 10.8 1.4e-11 44.2 1.8 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 EMT52245.1 - 0.0014 18.1 0.0 0.0033 16.9 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EMT52245.1 - 0.0085 15.9 0.2 0.04 13.7 0.1 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase FliT PF05400.13 EMT52246.1 - 3.9e-06 27.6 1.9 7.3e-06 26.7 1.9 1.6 1 1 0 1 1 1 1 Flagellar protein FliT FlgN PF05130.12 EMT52246.1 - 0.011 16.3 1.8 0.018 15.5 1.8 1.5 1 1 0 1 1 1 0 FlgN protein FliS PF02561.14 EMT52247.1 - 5.5e-38 129.8 2.0 6.2e-38 129.6 2.0 1.0 1 0 0 1 1 1 1 Flagellar protein FliS DUF1386 PF07138.11 EMT52247.1 - 0.017 14.4 0.0 0.019 14.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1386) FliD_C PF07195.12 EMT52248.1 - 2.4e-46 158.1 1.8 2.4e-46 158.1 1.8 2.1 3 0 0 3 3 3 1 Flagellar hook-associated protein 2 C-terminus FliD_N PF02465.18 EMT52248.1 - 5.7e-21 75.0 0.3 5.7e-21 75.0 0.3 3.1 3 0 0 3 3 3 1 Flagellar hook-associated protein 2 N-terminus CorA PF01544.18 EMT52248.1 - 0.015 14.7 1.0 1.4 8.2 0.2 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein MRFAP1 PF15155.6 EMT52248.1 - 0.024 15.1 0.0 0.05 14.1 0.0 1.5 1 0 0 1 1 1 0 MORF4 family-associated protein1 Adhesin_P1_N PF18652.1 EMT52248.1 - 0.068 13.2 5.2 2 8.5 0.5 3.3 3 0 0 3 3 3 0 Adhesin P1 N-terminal domain PulG PF11773.8 EMT52248.1 - 0.24 11.3 0.8 4.2 7.3 0.1 2.8 3 0 0 3 3 3 0 Type II secretory pathway pseudopilin 4HB_MCP_1 PF12729.7 EMT52248.1 - 0.6 9.6 5.2 0.15 11.6 0.8 2.2 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction FlaG PF03646.15 EMT52249.1 - 4.6e-24 84.5 0.8 5.1e-24 84.4 0.8 1.0 1 0 0 1 1 1 1 FlaG protein CTP_transf_3 PF02348.19 EMT52250.1 - 5.2e-28 98.5 0.0 6.1e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase IspD PF01128.19 EMT52250.1 - 0.00039 20.2 0.0 0.0005 19.9 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 EMT52250.1 - 0.00085 19.7 0.0 0.0012 19.2 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain Epimerase_2 PF02350.19 EMT52251.1 - 8.2e-76 255.1 0.0 9.3e-76 254.9 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_transf_9 PF01075.17 EMT52251.1 - 0.001 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) DUF354 PF04007.12 EMT52251.1 - 0.0069 15.5 0.0 0.02 13.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF354) ptaRNA1_toxin PF12703.7 EMT52251.1 - 0.057 13.5 0.0 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system Glyphos_transf PF04464.14 EMT52251.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase NeuB PF03102.14 EMT52252.1 - 2.7e-75 253.0 0.0 3.2e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 EMT52252.1 - 3.4e-11 43.6 0.0 8.7e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 SAF domain SET PF00856.28 EMT52252.1 - 0.036 14.4 0.1 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 SET domain BRF1 PF07741.13 EMT52252.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain MAF_flag10 PF01973.18 EMT52253.1 - 7.3e-38 129.9 0.1 1.6e-37 128.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF115 DNA_topoisoIV PF00521.20 EMT52253.1 - 0.095 11.6 1.4 0.16 10.8 1.4 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Flagellin_N PF00669.20 EMT52255.1 - 2.6e-42 144.2 11.1 2.6e-42 144.2 11.1 2.5 2 1 0 2 2 2 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 EMT52255.1 - 1.3e-29 102.4 8.8 1.3e-29 102.4 8.8 3.2 2 1 1 3 3 3 1 Bacterial flagellin C-terminal helical region DHR10 PF18595.1 EMT52255.1 - 0.0019 18.3 8.0 0.19 11.8 0.4 2.4 2 1 0 2 2 2 2 Designed helical repeat protein 10 domain FlxA PF14282.6 EMT52255.1 - 0.065 13.2 0.1 0.065 13.2 0.1 3.5 3 1 0 3 3 3 0 FlxA-like protein DUF2408 PF10303.9 EMT52255.1 - 0.068 13.7 1.4 1.6 9.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) XhlA PF10779.9 EMT52255.1 - 0.14 12.3 9.9 4.9 7.4 0.2 3.4 2 2 1 3 3 3 0 Haemolysin XhlA End3 PF12761.7 EMT52255.1 - 0.15 12.2 4.1 0.12 12.5 0.4 2.1 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 HlyD_2 PF12700.7 EMT52255.1 - 0.25 10.1 6.2 0.39 9.4 0.9 2.1 2 0 0 2 2 2 0 HlyD family secretion protein zf-ZPR1 PF03367.13 EMT52255.1 - 0.66 9.8 3.1 0.72 9.7 0.8 2.1 1 1 1 2 2 2 0 ZPR1 zinc-finger domain Cytochrom_B562 PF07361.11 EMT52255.1 - 1.7 9.3 6.2 0.84 10.3 0.6 2.9 2 2 1 3 3 3 0 Cytochrome b562 ERM PF00769.19 EMT52255.1 - 2.5 7.8 9.4 0.36 10.6 0.4 2.5 2 1 0 3 3 3 0 Ezrin/radixin/moesin family FlaC_arch PF05377.11 EMT52255.1 - 3.6 8.1 8.2 11 6.5 0.2 3.6 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) CsrA PF02599.16 EMT52256.1 - 2.7e-27 94.5 3.9 3.6e-27 94.1 3.9 1.2 1 0 0 1 1 1 1 Global regulator protein family YscO-like PF16789.5 EMT52256.1 - 0.011 15.7 0.2 0.011 15.7 0.2 1.1 1 0 0 1 1 1 0 YscO-like protein Med10 PF09748.9 EMT52256.1 - 0.029 14.3 0.1 0.032 14.2 0.1 1.2 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex S1 PF00575.23 EMT52256.1 - 0.05 13.9 0.8 0.084 13.2 0.4 1.5 1 1 0 1 1 1 0 S1 RNA binding domain FliW PF02623.15 EMT52257.1 - 9e-37 125.6 0.1 1.1e-36 125.4 0.1 1.1 1 0 0 1 1 1 1 FliW protein Flagellin_N PF00669.20 EMT52259.1 - 1.5e-25 89.9 2.0 1.5e-25 89.9 2.0 2.0 2 1 0 2 2 2 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 EMT52259.1 - 1.2e-07 32.0 0.5 1.2e-07 32.0 0.5 3.2 3 0 0 3 3 3 1 Bacterial flagellin C-terminal helical region Spectrin PF00435.21 EMT52259.1 - 0.0037 17.7 0.5 0.37 11.3 0.0 2.8 2 1 0 2 2 2 1 Spectrin repeat ECM11 PF15463.6 EMT52259.1 - 0.11 13.1 0.8 14 6.2 0.1 2.5 2 0 0 2 2 2 0 Extracellular mutant protein 11 CdvA PF18822.1 EMT52259.1 - 0.11 12.3 5.1 0.99 9.2 0.1 3.7 2 2 2 4 4 4 0 CdvA-like coiled-coil domain DP PF08781.10 EMT52259.1 - 0.96 9.3 4.5 0.34 10.8 0.9 2.0 2 0 0 2 2 2 0 Transcription factor DP Flg_bbr_C PF06429.13 EMT52260.1 - 2.4e-13 50.0 1.9 2.4e-13 50.0 1.9 2.4 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 EMT52260.1 - 1.7e-07 31.0 0.3 1.7e-07 31.0 0.3 2.4 2 0 0 2 2 2 1 Flagella basal body rod protein Baculo_PEP_C PF04513.12 EMT52260.1 - 0.043 13.8 0.2 3 7.9 0.1 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med11 PF10280.9 EMT52260.1 - 0.074 13.5 0.1 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 Mediator complex protein DUF2408 PF10303.9 EMT52260.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) FlgN PF05130.12 EMT52261.1 - 2.9e-27 96.0 7.9 3.1e-27 95.9 7.9 1.0 1 0 0 1 1 1 1 FlgN protein NMT1_2 PF13379.6 EMT52261.1 - 0.058 13.1 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family Peptidase_S15 PF02129.18 EMT52261.1 - 0.061 12.9 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FliT PF05400.13 EMT52261.1 - 0.17 12.7 9.7 0.51 11.2 4.2 2.4 1 1 1 2 2 2 0 Flagellar protein FliT Succ_DH_flav_C PF02910.20 EMT52261.1 - 0.26 11.3 3.0 0.32 11.0 0.5 2.0 2 0 0 2 2 2 0 Fumarate reductase flavoprotein C-term FlgM PF04316.13 EMT52262.1 - 1.1e-13 51.3 0.2 1.4e-13 50.9 0.2 1.2 1 0 0 1 1 1 1 Anti-sigma-28 factor, FlgM FeoB_Cyto PF17910.1 EMT52262.1 - 0.051 14.1 0.1 0.063 13.8 0.1 1.2 1 0 0 1 1 1 0 FeoB cytosolic helical domain TcdB_N PF12918.7 EMT52262.1 - 0.11 12.8 0.7 0.27 11.5 0.2 1.9 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain zinc-ribbons_6 PF07191.12 EMT52263.1 - 0.00048 20.0 5.1 0.4 10.7 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbons zf-C4pol PF14260.6 EMT52263.1 - 0.024 15.1 10.5 0.43 11.1 2.2 2.2 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta HTH_25 PF13413.6 EMT52263.1 - 0.025 14.4 0.3 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain SVIP PF15811.5 EMT52263.1 - 0.034 14.6 1.8 0.034 14.6 1.8 1.9 2 0 0 2 2 2 0 Small VCP/p97-interacting protein DZR PF12773.7 EMT52263.1 - 0.058 13.4 8.1 0.98 9.5 8.1 2.4 1 1 0 1 1 1 0 Double zinc ribbon MerR PF00376.23 EMT52263.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein HTH_3 PF01381.22 EMT52263.1 - 0.11 12.5 0.3 0.3 11.2 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix PolC_DP2 PF03833.13 EMT52263.1 - 2.5 5.9 7.6 1.7 6.4 0.4 2.0 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 Pribosyltran PF00156.27 EMT52264.1 - 4.7e-07 29.4 0.0 8.2e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain His_Phos_1 PF00300.22 EMT52264.1 - 0.047 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) PRTase_2 PF15609.6 EMT52264.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Helicase_C PF00271.31 EMT52265.1 - 4e-11 43.2 0.0 7.8e-10 39.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMT52265.1 - 5.1e-07 29.9 0.0 9.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMT52265.1 - 2.7e-06 27.3 0.0 5.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EMT52265.1 - 0.067 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EMT52265.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Response_reg PF00072.24 EMT52267.1 - 1.9e-29 102.1 0.1 3.2e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EMT52267.1 - 2.1e-22 78.4 0.8 8.1e-22 76.5 0.5 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EMT52267.1 - 5.6e-07 29.1 0.1 1.1e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT52267.1 - 1.9e-05 24.1 0.3 4e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 EMT52267.1 - 0.0037 17.0 0.0 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain DUF3782 PF12644.7 EMT52267.1 - 0.014 15.5 1.1 13 6.0 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3782) HTH_38 PF13936.6 EMT52267.1 - 0.024 14.4 0.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DegS PF05384.11 EMT52268.1 - 1.5e-60 203.3 13.2 1.5e-60 203.3 13.2 2.2 2 0 0 2 2 2 1 Sensor protein DegS HisKA_3 PF07730.13 EMT52268.1 - 2.3e-14 53.6 11.7 2.8e-14 53.4 3.4 3.6 3 0 0 3 3 3 1 Histidine kinase HATPase_c PF02518.26 EMT52268.1 - 3.2e-09 37.3 0.0 1.4e-08 35.2 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT52268.1 - 0.0015 18.5 0.1 0.0076 16.2 0.0 2.2 2 1 0 2 2 2 1 Histidine kinase-like ATPase domain Pih1_fungal_CS PF18482.1 EMT52268.1 - 0.0019 18.7 1.0 0.0044 17.5 0.4 1.9 2 0 0 2 2 2 1 Fungal Pih1 CS domain HATPase_c_3 PF13589.6 EMT52268.1 - 0.016 15.0 0.0 0.048 13.5 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3450 PF11932.8 EMT52268.1 - 0.046 13.0 10.3 0.99 8.7 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FemAB PF02388.16 EMT52268.1 - 0.049 12.5 0.8 0.084 11.7 0.8 1.5 1 0 0 1 1 1 0 FemAB family DUF1664 PF07889.12 EMT52268.1 - 0.14 12.2 10.6 1.3 9.1 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 EMT52268.1 - 0.14 11.2 11.7 0.34 9.9 10.9 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1043 PF06295.12 EMT52268.1 - 0.18 11.8 4.3 0.19 11.7 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Syntaxin-6_N PF09177.11 EMT52268.1 - 0.35 11.4 11.4 0.68 10.5 2.0 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal SpoIISA_toxin PF14171.6 EMT52268.1 - 0.76 9.4 6.1 0.22 11.2 0.1 2.5 2 1 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system DUF2968 PF11180.8 EMT52268.1 - 1.3 8.7 15.4 0.049 13.3 1.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) TMF_DNA_bd PF12329.8 EMT52268.1 - 2.5 8.1 11.4 3.3 7.8 0.2 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.17 EMT52268.1 - 4 7.4 10.9 2.4 8.1 4.3 3.3 2 1 1 3 3 3 0 Prefoldin subunit DUF4407 PF14362.6 EMT52268.1 - 5.2 6.3 10.4 45 3.3 10.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BRE1 PF08647.11 EMT52268.1 - 9.8 6.3 14.5 0.97 9.5 1.4 3.7 4 0 0 4 4 4 0 BRE1 E3 ubiquitin ligase Polysacc_deac_1 PF01522.21 EMT52269.1 - 1.4e-20 73.4 0.0 2.4e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase S-AdoMet_synt_C PF02773.16 EMT52270.1 - 6.7e-72 239.9 0.6 1.5e-71 238.8 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EMT52270.1 - 8e-52 174.6 0.0 2.1e-51 173.2 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EMT52270.1 - 8.3e-45 151.5 0.1 1.9e-44 150.4 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EMT52270.1 - 0.092 11.5 0.1 0.27 10.0 0.0 1.8 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Peptidase_S8 PF00082.22 EMT52272.1 - 2.2e-46 158.5 1.8 3.5e-46 157.8 1.8 1.3 1 0 0 1 1 1 1 Subtilase family SLH PF00395.20 EMT52272.1 - 1.5e-42 143.4 0.7 8.1e-14 51.4 0.0 3.9 4 0 0 4 4 4 3 S-layer homology domain PPC PF04151.15 EMT52272.1 - 7.4e-06 27.0 1.4 0.39 11.9 0.1 4.0 3 0 0 3 3 3 2 Bacterial pre-peptidase C-terminal domain Peripla_BP_4 PF13407.6 EMT52272.1 - 0.012 15.2 1.2 0.026 14.1 0.4 1.9 1 1 1 2 2 2 0 Periplasmic binding protein domain GDPD PF03009.17 EMT52272.1 - 0.043 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Asparaginase_C PF17763.1 EMT52272.1 - 0.071 13.3 0.3 22 5.3 0.1 2.7 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain Lipin_N PF04571.14 EMT52272.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 lipin, N-terminal conserved region Ku PF02735.16 EMT52273.1 - 0.072 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain DUF3426 PF11906.8 EMT52273.1 - 0.17 12.0 0.0 17 5.5 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3426) MutL_C PF08676.11 EMT52274.1 - 0.081 12.7 0.3 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 MutL C terminal dimerisation domain LEA_2 PF03168.13 EMT52274.1 - 0.1 13.1 0.0 0.53 10.8 0.0 2.1 2 0 0 2 2 2 0 Late embryogenesis abundant protein Rtt102p PF09510.10 EMT52274.1 - 4.7 7.4 5.4 1 9.6 1.3 1.9 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein DUF3426 PF11906.8 EMT52275.1 - 7.5e-06 26.2 0.0 0.0018 18.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3426) Cu_amine_oxidN1 PF07833.11 EMT52276.1 - 1.1e-35 121.9 0.4 5.2e-25 87.8 0.1 3.4 2 1 1 3 3 3 2 Copper amine oxidase N-terminal domain Macoilin PF09726.9 EMT52276.1 - 0.75 8.3 36.2 0.013 14.1 29.3 1.4 2 0 0 2 2 2 0 Macoilin family Peptidase_S64 PF08192.11 EMT52276.1 - 1.2 7.5 18.9 2.1 6.7 18.9 1.4 1 0 0 1 1 1 0 Peptidase family S64 Rrn6 PF10214.9 EMT52276.1 - 6 5.2 11.7 10 4.5 11.7 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Cupin_2 PF07883.11 EMT52277.1 - 2.8e-18 65.4 0.0 4.3e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain HTH_3 PF01381.22 EMT52277.1 - 6.9e-13 48.4 0.4 9.3e-13 48.0 0.4 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EMT52277.1 - 8.1e-09 35.7 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EMT52277.1 - 1.2e-07 31.7 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EMT52277.1 - 5.8e-05 23.5 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EMT52277.1 - 0.00015 21.5 0.9 0.00034 20.4 0.7 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain AraC_binding PF02311.19 EMT52277.1 - 0.0046 16.9 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 EMT52277.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) HTH_35 PF13693.6 EMT52277.1 - 0.011 15.8 0.1 0.022 14.8 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.16 EMT52278.1 - 2.7e-28 98.9 76.5 7.8e-23 81.0 43.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT52278.1 - 1.1e-24 87.1 26.0 3.6e-20 72.3 8.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter GTA_holin_3TM PF11351.8 EMT52278.1 - 0.61 10.6 4.2 1.9 9.1 0.9 2.5 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release OCD_Mu_crystall PF02423.15 EMT52279.1 - 7.5e-78 261.7 0.7 8.4e-78 261.5 0.7 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EMT52279.1 - 2.6e-08 34.0 0.0 4.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EMT52279.1 - 0.0026 18.3 0.2 0.007 16.9 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Gal4_dimer PF03902.13 EMT52279.1 - 0.012 15.7 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain NAD_binding_7 PF13241.6 EMT52279.1 - 0.023 15.1 0.2 0.63 10.5 0.2 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF5616 PF18481.1 EMT52279.1 - 0.034 14.5 0.2 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5616) MFS_4 PF06779.14 EMT52280.1 - 0.0061 15.9 0.1 0.0071 15.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MucBP_2 PF17965.1 EMT52280.1 - 0.66 10.6 5.2 9.3 6.9 0.2 2.3 1 1 1 2 2 2 0 Mucin binding domain MazE_antitoxin PF04014.18 EMT52281.1 - 4.5e-07 29.7 0.0 7.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin T3SS_needle_E PF08988.10 EMT52281.1 - 0.029 14.5 0.2 10 6.4 0.0 2.3 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle MraZ PF02381.18 EMT52281.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like HECA PF15353.6 EMT52281.1 - 0.26 11.5 4.6 1.3 9.3 0.3 2.3 1 1 1 2 2 2 0 Headcase protein family homologue UPF0506 PF11703.8 EMT52281.1 - 6.8 7.2 11.2 0.46 10.9 0.3 2.8 3 0 0 3 3 3 0 UPF0506 Big_2 PF02368.18 EMT52282.1 - 3.2e-11 42.9 15.5 3.4e-07 30.1 4.4 5.6 5 2 2 7 7 7 2 Bacterial Ig-like domain (group 2) Phage_integrase PF00589.22 EMT52283.1 - 6.1e-40 136.8 0.3 5.5e-39 133.7 0.1 2.0 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 EMT52283.1 - 4.2e-13 49.4 0.6 8.6e-13 48.4 0.6 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 EMT52283.1 - 5.5e-11 42.8 1.2 1.2e-10 41.7 1.2 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 EMT52283.1 - 4.5e-08 33.3 1.4 2.3e-07 31.1 1.4 2.2 1 1 0 1 1 1 1 Phage integrase SAM-like domain Hjc PF01870.18 EMT52283.1 - 0.016 15.2 0.3 0.51 10.4 0.2 2.4 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) Titin_Ig-rpts PF06582.12 EMT52283.1 - 0.042 13.8 0.6 0.17 11.9 0.6 2.1 1 0 0 1 1 1 0 Titin repeat YolD PF08863.10 EMT52283.1 - 0.11 12.6 1.4 0.19 11.8 0.2 2.0 2 0 0 2 2 2 0 YolD-like protein HTH_38 PF13936.6 EMT52284.1 - 0.0045 16.7 0.0 0.38 10.5 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_18 PF12833.7 EMT52284.1 - 0.0086 16.3 0.1 1.3 9.3 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain GerE PF00196.19 EMT52284.1 - 0.025 14.1 0.0 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family ATP_bind_3 PF01171.20 EMT52284.1 - 0.059 13.1 1.0 2.8 7.6 0.0 2.3 1 1 1 2 2 2 0 PP-loop family HTH_23 PF13384.6 EMT52284.1 - 0.12 12.2 0.0 6.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain Glug PF07581.12 EMT52285.1 - 9.2e-20 69.7 35.9 0.0074 16.6 0.6 9.9 10 0 0 10 10 10 7 The GLUG motif DUF3704 PF12488.8 EMT52285.1 - 0.063 12.9 0.8 0.15 11.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) T_cell_tran_alt PF15128.6 EMT52285.1 - 0.17 11.7 1.2 12 5.8 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Endotoxin_C2 PF18449.1 EMT52286.1 - 6.4e-29 100.1 25.2 1.3e-17 63.9 8.5 6.7 5 1 2 7 7 7 2 Delta endotoxin CopC PF04234.12 EMT52286.1 - 1.8e-05 25.7 13.8 0.19 12.8 0.1 6.1 5 0 0 5 5 5 3 CopC domain Big_5 PF13205.6 EMT52286.1 - 0.0023 18.6 0.8 0.0023 18.6 0.8 6.8 4 2 1 6 6 6 2 Bacterial Ig-like domain DUF2621 PF11084.8 EMT52286.1 - 0.37 10.8 1.7 2.2 8.2 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2621) Spc7 PF08317.11 EMT52286.1 - 1.2 7.9 26.1 2.2 7.1 5.7 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein SLH PF00395.20 EMT52287.1 - 2.2e-21 75.6 3.0 1.7e-11 43.9 0.4 3.8 3 0 0 3 3 3 2 S-layer homology domain Big_6 PF17936.1 EMT52287.1 - 0.0016 18.6 1.5 0.0016 18.6 1.5 3.3 3 0 0 3 3 3 1 Bacterial Ig domain DUF3244 PF11589.8 EMT52287.1 - 0.018 15.1 2.0 3.1 7.9 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3244) Biotin_lipoyl_2 PF13533.6 EMT52287.1 - 0.082 12.7 0.1 0.55 10.1 0.2 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like OEP PF02321.18 EMT52288.1 - 4.3e-29 101.7 51.7 2.6e-17 63.2 15.0 4.2 3 1 1 4 4 4 3 Outer membrane efflux protein UPF0029 PF01205.19 EMT52289.1 - 1.8e-31 108.6 0.1 3.4e-31 107.7 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 EMT52289.1 - 6.5e-15 54.8 0.6 1.2e-14 53.9 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1949) EFG_C PF00679.24 EMT52289.1 - 0.00081 19.4 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Imm74 PF15603.6 EMT52289.1 - 0.002 18.3 0.1 0.085 13.1 0.0 2.4 2 0 0 2 2 2 1 Immunity protein 74 DUF1664 PF07889.12 EMT52290.1 - 4.6e-10 39.6 4.8 0.00013 22.0 0.1 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) EzrA PF06160.12 EMT52290.1 - 2.9e-09 35.7 6.7 5.9e-09 34.7 6.7 1.5 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA BLOC1_2 PF10046.9 EMT52290.1 - 2.9e-08 33.9 0.3 0.064 13.6 0.1 3.9 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 EMT52290.1 - 1.2e-07 32.1 10.0 0.0014 19.1 8.4 3.5 1 1 0 1 1 1 1 Protein of unknown function DUF16 Exonuc_VII_L PF02601.15 EMT52290.1 - 1.9e-07 30.9 5.6 3.9e-06 26.6 0.4 2.0 1 1 1 2 2 2 2 Exonuclease VII, large subunit RmuC PF02646.16 EMT52290.1 - 3.2e-07 29.8 4.1 0.0032 16.7 0.4 3.0 1 1 3 4 4 4 2 RmuC family Spc7 PF08317.11 EMT52290.1 - 3.6e-07 29.4 7.6 0.00026 20.0 1.7 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 EMT52290.1 - 1.1e-06 28.8 14.3 0.00055 20.1 2.5 3.3 1 1 2 3 3 3 2 Tropomyosin like FlaC_arch PF05377.11 EMT52290.1 - 1.3e-06 28.7 1.0 1.7 9.1 0.0 4.8 1 1 3 4 4 4 1 Flagella accessory protein C (FlaC) Tropomyosin PF00261.20 EMT52290.1 - 1.9e-06 27.5 14.0 2.9e-06 26.8 14.0 1.3 1 0 0 1 1 1 1 Tropomyosin IFT57 PF10498.9 EMT52290.1 - 1.9e-06 27.1 1.8 0.0054 15.7 0.0 2.4 1 1 2 3 3 3 2 Intra-flagellar transport protein 57 Laminin_II PF06009.12 EMT52290.1 - 2.4e-06 27.6 0.4 0.008 16.2 0.0 3.4 1 1 2 3 3 3 1 Laminin Domain II Occludin_ELL PF07303.13 EMT52290.1 - 2.9e-06 27.9 12.9 0.0079 16.9 1.9 3.4 1 1 1 3 3 3 2 Occludin homology domain Nup54 PF13874.6 EMT52290.1 - 4.6e-06 26.8 4.7 7.8e-05 22.8 2.7 2.7 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 ABC_tran_CTD PF16326.5 EMT52290.1 - 1.2e-05 25.5 3.3 0.46 10.8 0.0 4.4 1 1 3 4 4 4 1 ABC transporter C-terminal domain Fib_alpha PF08702.10 EMT52290.1 - 1.7e-05 25.0 2.6 0.035 14.3 1.1 3.1 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family GAS PF13851.6 EMT52290.1 - 2.3e-05 23.8 12.3 0.00025 20.5 8.2 3.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF3552 PF12072.8 EMT52290.1 - 3.8e-05 23.2 16.0 0.061 12.7 10.1 3.5 1 1 0 2 2 2 1 Domain of unknown function (DUF3552) TMPIT PF07851.13 EMT52290.1 - 3.9e-05 23.0 1.6 0.0019 17.5 0.1 2.2 1 1 1 2 2 2 2 TMPIT-like protein SOAR PF16533.5 EMT52290.1 - 6e-05 22.9 14.8 0.13 12.2 1.1 4.5 1 1 3 4 4 4 2 STIM1 Orai1-activating region Hemagglutinin PF00509.18 EMT52290.1 - 6.6e-05 21.5 7.4 0.032 12.6 0.1 3.0 1 1 2 3 3 3 2 Haemagglutinin Matrilin_ccoil PF10393.9 EMT52290.1 - 6.7e-05 22.7 0.4 34 4.4 0.0 5.3 1 1 6 7 7 7 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF948 PF06103.11 EMT52290.1 - 7.7e-05 22.9 0.0 0.7 10.2 0.1 3.6 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) PilJ PF13675.6 EMT52290.1 - 0.00011 22.2 2.6 0.6 10.2 2.7 3.3 1 1 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3450 PF11932.8 EMT52290.1 - 0.00014 21.3 13.8 0.0021 17.4 5.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) FapA PF03961.13 EMT52290.1 - 0.00025 19.8 0.8 0.0068 15.1 0.2 2.2 1 1 2 3 3 3 3 Flagellar Assembly Protein A DUF2959 PF11172.8 EMT52290.1 - 0.0003 21.0 7.6 0.15 12.2 3.4 3.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2959) MCPsignal PF00015.21 EMT52290.1 - 0.00035 20.4 0.0 0.03 14.1 0.0 2.2 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain V-SNARE_C PF12352.8 EMT52290.1 - 0.00038 20.7 0.8 22 5.4 0.0 4.4 2 1 3 5 5 4 0 Snare region anchored in the vesicle membrane C-terminus KxDL PF10241.9 EMT52290.1 - 0.00041 20.6 12.2 0.64 10.3 0.4 4.5 1 1 4 5 5 5 1 Uncharacterized conserved protein DUF745 PF05335.13 EMT52290.1 - 0.00052 19.8 0.0 0.065 12.9 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF745) FH2 PF02181.23 EMT52290.1 - 0.0006 19.0 8.9 0.0055 15.9 3.0 2.1 1 1 1 2 2 2 2 Formin Homology 2 Domain Phage_GPO PF05929.11 EMT52290.1 - 0.00066 19.4 3.9 0.062 12.9 3.9 2.6 1 1 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase NPV_P10 PF05531.12 EMT52290.1 - 0.00072 20.0 1.7 1.8 9.1 0.7 4.1 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF4256 PF14066.6 EMT52290.1 - 0.0013 18.4 4.6 0.12 12.0 0.1 3.5 1 1 1 2 2 2 1 Protein of unknown function (DUF4256) COG6 PF06419.11 EMT52290.1 - 0.0014 17.0 1.0 0.43 8.7 0.1 2.7 1 1 2 3 3 3 2 Conserved oligomeric complex COG6 STAT_alpha PF01017.20 EMT52290.1 - 0.0017 18.3 7.6 0.016 15.1 3.4 2.4 1 1 1 2 2 2 1 STAT protein, all-alpha domain Peptidase_M75 PF09375.10 EMT52290.1 - 0.0026 17.3 7.8 2.1 7.8 0.3 3.9 1 1 3 4 4 4 1 Imelysin CENP-F_leu_zip PF10473.9 EMT52290.1 - 0.0029 17.6 0.9 0.0029 17.6 0.9 2.0 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ISG65-75 PF11727.8 EMT52290.1 - 0.003 16.9 0.3 0.092 12.0 0.1 2.4 1 1 1 2 2 2 1 Invariant surface glycoprotein FPP PF05911.11 EMT52290.1 - 0.0031 15.8 0.5 0.0053 15.0 0.5 1.5 1 1 0 1 1 1 1 Filament-like plant protein, long coiled-coil CLZ PF16526.5 EMT52290.1 - 0.0037 17.6 11.3 8.2 6.9 0.3 5.0 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DHR10 PF18595.1 EMT52290.1 - 0.006 16.6 13.5 0.9 9.6 1.6 3.4 2 1 1 3 3 3 1 Designed helical repeat protein 10 domain Allexi_40kDa PF05549.11 EMT52290.1 - 0.0063 16.1 0.2 0.064 12.8 0.0 2.5 1 1 0 1 1 1 1 Allexivirus 40kDa protein Laminin_I PF06008.14 EMT52290.1 - 0.011 15.5 0.8 0.7 9.6 0.2 2.5 1 1 1 2 2 2 0 Laminin Domain I V_ATPase_I PF01496.19 EMT52290.1 - 0.012 13.5 14.2 0.045 11.7 4.9 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family WXG100 PF06013.12 EMT52290.1 - 0.014 15.6 5.2 8.1 6.8 0.2 4.1 1 1 3 5 5 5 0 Proteins of 100 residues with WXG Prefoldin_2 PF01920.20 EMT52290.1 - 0.027 14.4 5.6 5.3 7.1 0.1 4.3 1 1 1 3 3 3 0 Prefoldin subunit WASH_WAHD PF11945.8 EMT52290.1 - 0.033 13.7 12.0 0.16 11.5 0.1 3.3 1 1 2 3 3 3 0 WAHD domain of WASH complex Mst1_SARAH PF11629.8 EMT52290.1 - 0.038 14.1 12.0 0.63 10.2 0.1 5.5 1 1 1 2 2 1 0 C terminal SARAH domain of Mst1 DUF4363 PF14276.6 EMT52290.1 - 0.039 14.1 0.8 2.3 8.4 0.2 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) DUF3782 PF12644.7 EMT52290.1 - 0.046 13.9 11.0 1.7e+02 2.5 6.8 4.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3782) Imm7 PF15585.6 EMT52290.1 - 0.051 13.9 1.3 5.5 7.3 0.1 3.1 1 1 1 2 2 2 0 Immunity protein 7 MscS_porin PF12795.7 EMT52290.1 - 0.059 12.9 0.0 3.6 7.0 0.0 2.3 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain OSCP PF00213.18 EMT52290.1 - 0.082 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit SHE3 PF17078.5 EMT52290.1 - 0.085 12.6 12.4 1.2 8.8 0.8 3.4 1 1 3 4 4 4 0 SWI5-dependent HO expression protein 3 DUF4795 PF16043.5 EMT52290.1 - 0.1 12.2 14.0 2.8 7.5 0.5 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) TMF_TATA_bd PF12325.8 EMT52290.1 - 0.16 12.2 8.2 0.33 11.2 1.5 3.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Nup88 PF10168.9 EMT52290.1 - 0.17 9.7 7.1 0.2 9.4 6.0 1.7 1 1 0 1 1 1 0 Nuclear pore component DUF730 PF05325.11 EMT52290.1 - 0.18 11.8 13.5 7.5 6.6 0.5 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF730) HAUS4 PF14735.6 EMT52290.1 - 0.2 11.3 14.3 12 5.5 0.5 4.5 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 4 TACC_C PF05010.14 EMT52290.1 - 0.29 10.9 12.0 0.65 9.8 6.9 2.9 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal XhlA PF10779.9 EMT52290.1 - 0.33 11.2 11.8 1 9.6 0.2 4.0 2 1 3 5 5 4 0 Haemolysin XhlA TRPM_tetra PF16519.5 EMT52290.1 - 0.34 11.0 12.4 9.5 6.4 0.4 4.2 1 1 4 5 5 4 0 Tetramerisation domain of TRPM MbeD_MobD PF04899.12 EMT52290.1 - 0.4 10.8 5.1 1.5 9.0 0.5 3.2 2 1 0 2 2 2 0 MbeD/MobD like DUF4665 PF15679.5 EMT52290.1 - 0.46 11.1 3.8 31 5.3 1.9 3.7 1 1 0 2 2 1 0 Domain of unknown function (DUF4665) Prefoldin_3 PF13758.6 EMT52290.1 - 0.51 10.4 16.2 11 6.2 0.6 4.8 1 1 3 5 5 5 0 Prefoldin subunit DUF724 PF05266.14 EMT52290.1 - 1.1 9.1 12.4 1 9.2 3.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) pXO2-34 PF17362.2 EMT52290.1 - 1.3 8.9 7.8 96 3.0 0.1 4.1 1 1 6 7 7 7 0 Family of unknown function Sec2p PF06428.11 EMT52290.1 - 1.9 8.5 9.9 18 5.4 0.3 4.0 1 1 3 4 4 4 0 GDP/GTP exchange factor Sec2p PRKG1_interact PF15898.5 EMT52290.1 - 2.1 9.3 11.9 27 5.7 3.0 3.3 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain MtrG PF04210.13 EMT52290.1 - 2.4 8.1 23.8 39 4.2 1.1 6.2 1 1 3 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G APG6_N PF17675.1 EMT52290.1 - 4.9 7.7 12.8 5.6 7.5 1.9 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Cortex-I_coil PF09304.10 EMT52290.1 - 5.2 7.3 13.4 24 5.2 2.9 3.5 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF4164 PF13747.6 EMT52290.1 - 9.2 6.6 22.2 1.9 8.8 6.9 3.4 2 1 3 5 5 4 0 Domain of unknown function (DUF4164) Jnk-SapK_ap_N PF09744.9 EMT52290.1 - 9.6 6.4 15.6 0.38 11.0 1.2 3.0 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 SLH PF00395.20 EMT52291.1 - 7.8e-28 96.2 5.8 9.2e-12 44.8 0.0 4.4 4 0 0 4 4 4 3 S-layer homology domain Glycos_transf_4 PF00953.21 EMT52292.1 - 2.2e-41 141.5 19.9 2.2e-41 141.5 19.9 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 4 Glyco_tran_WecB PF03808.13 EMT52293.1 - 6.8e-65 218.1 1.8 1e-64 217.5 1.4 1.5 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family STAS_2 PF13466.6 EMT52293.1 - 0.092 13.1 0.4 0.34 11.3 0.2 2.0 2 0 0 2 2 2 0 STAS domain FabA PF07977.13 EMT52294.1 - 1.5e-35 121.8 0.0 1.7e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 EMT52294.1 - 4.2e-05 23.1 0.1 6.2e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 MaoC like domain 4HBT PF03061.22 EMT52294.1 - 0.00049 20.4 0.0 0.00068 19.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydrat_N PF13452.6 EMT52294.1 - 0.086 13.0 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase CDP-OH_P_transf PF01066.21 EMT52295.1 - 1.7e-15 57.6 0.3 1.7e-15 57.6 0.3 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase EpuA PF11772.8 EMT52296.1 - 8.1e-12 44.6 0.5 1.3e-11 44.0 0.5 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase subunit beta Flg_bbr_C PF06429.13 EMT52297.1 - 1.9e-17 63.2 2.7 1.9e-17 63.2 2.7 1.8 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 EMT52297.1 - 2e-06 27.6 4.3 4.9e-06 26.4 4.3 1.7 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 EMT52298.1 - 6.2e-21 74.3 0.8 1.8e-20 72.9 0.8 1.8 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 EMT52298.1 - 1.5e-10 40.8 0.4 4.1e-10 39.4 0.4 1.8 1 0 0 1 1 1 1 Flagella basal body rod protein MreB_Mbl PF06723.13 EMT52299.1 - 1.4e-147 490.7 8.8 1.6e-147 490.6 8.8 1.0 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 EMT52299.1 - 2.2e-10 40.9 2.3 2.4e-10 40.7 0.2 2.1 2 0 0 2 2 2 1 Cell division protein FtsA Actin PF00022.19 EMT52299.1 - 5.2e-10 38.5 0.0 2e-06 26.7 0.0 2.0 2 0 0 2 2 2 2 Actin HSP70 PF00012.20 EMT52299.1 - 6.7e-09 34.5 0.6 1.4e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Hsp70 protein EutA PF06277.11 EMT52299.1 - 2.6e-06 26.6 4.8 8.6e-06 24.9 1.5 2.1 1 1 1 2 2 2 1 Ethanolamine utilisation protein EutA DDR PF08841.10 EMT52299.1 - 9e-05 21.6 1.6 0.0003 19.9 0.7 2.0 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain PilM_2 PF11104.8 EMT52299.1 - 0.00016 20.8 0.1 0.05 12.6 0.0 2.5 3 0 0 3 3 3 2 Type IV pilus assembly protein PilM; Ppx-GppA PF02541.16 EMT52299.1 - 0.01 15.3 0.2 0.029 13.8 0.2 1.6 2 0 0 2 2 2 0 Ppx/GppA phosphatase family MutL PF13941.6 EMT52299.1 - 0.018 13.7 0.1 0.029 13.0 0.1 1.3 1 0 0 1 1 1 0 MutL protein SpoIIID PF12116.8 EMT52300.1 - 4.1e-41 138.9 2.6 4.9e-41 138.7 2.6 1.0 1 0 0 1 1 1 1 Stage III sporulation protein D HTH_7 PF02796.15 EMT52300.1 - 0.00045 20.2 0.1 0.01 15.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 EMT52300.1 - 0.0007 19.5 0.1 0.0012 18.7 0.1 1.4 1 0 0 1 1 1 1 HTH domain HTH_10 PF04967.12 EMT52300.1 - 0.002 17.9 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 HTH DNA binding domain HTH_23 PF13384.6 EMT52300.1 - 0.003 17.3 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain LacI PF00356.21 EMT52300.1 - 0.0061 16.3 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family LZ_Tnp_IS481 PF13011.6 EMT52300.1 - 0.0089 16.5 0.0 0.02 15.4 0.0 1.5 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_22 PF13309.6 EMT52300.1 - 0.0092 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_38 PF13936.6 EMT52300.1 - 0.013 15.3 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_DeoR PF08220.12 EMT52300.1 - 0.014 15.2 0.3 0.035 13.8 0.1 1.9 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_IclR PF09339.10 EMT52300.1 - 0.017 14.9 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_28 PF13518.6 EMT52300.1 - 0.023 14.8 0.4 0.048 13.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain TetR_N PF00440.23 EMT52300.1 - 0.05 13.4 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family GntR PF00392.21 EMT52300.1 - 0.051 13.2 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Sigma70_r4 PF04545.16 EMT52300.1 - 0.054 13.0 0.5 0.25 10.9 0.1 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_40 PF14493.6 EMT52300.1 - 0.057 13.9 0.2 0.081 13.4 0.2 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EMT52300.1 - 0.068 13.2 0.2 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_4 PF13613.6 EMT52300.1 - 0.12 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.6 EMT52300.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Peptidase_M23 PF01551.22 EMT52301.1 - 6.7e-24 83.9 0.2 1.1e-23 83.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M23 Biotin_lipoyl_2 PF13533.6 EMT52301.1 - 0.014 15.2 4.3 0.069 13.0 0.2 3.3 4 0 0 4 4 4 0 Biotin-lipoyl like RnfC_N PF13375.6 EMT52301.1 - 0.033 14.2 0.8 0.75 9.8 0.1 2.9 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EMT52301.1 - 0.061 13.2 1.3 0.48 10.3 0.3 2.8 2 1 0 2 2 2 0 Biotin-requiring enzyme SpoIID PF08486.10 EMT52302.1 - 2.2e-24 85.8 1.1 3.4e-24 85.2 1.1 1.3 1 0 0 1 1 1 1 Stage II sporulation protein Mrr_cat PF04471.12 EMT52302.1 - 0.1 12.6 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Restriction endonuclease DUF2798 PF11391.8 EMT52302.1 - 0.23 11.5 1.9 0.4 10.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) EPSP_synthase PF00275.20 EMT52303.1 - 5.9e-114 381.0 6.1 6.9e-114 380.8 6.1 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DUF1779 PF08680.10 EMT52304.1 - 7.4e-32 111.2 0.0 1e-31 110.8 0.0 1.1 1 0 0 1 1 1 1 TATA-box binding DUF1146 PF06612.11 EMT52305.1 - 1.9e-17 63.0 2.1 2.2e-17 62.8 1.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1146) Proton_antipo_M PF00361.20 EMT52306.1 - 5.6e-67 226.0 29.4 5.6e-67 226.0 29.4 1.9 2 0 0 2 2 2 1 Proton-conducting membrane transporter DUF1358 PF07096.11 EMT52306.1 - 0.15 12.1 2.0 0.43 10.6 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) Proton_antipo_M PF00361.20 EMT52307.1 - 2.7e-67 227.0 33.7 2.7e-67 227.0 33.7 2.1 3 0 0 3 3 3 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 EMT52307.1 - 5.1e-06 26.5 1.4 5.1e-06 26.5 1.4 4.4 2 1 0 3 3 3 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus DUF1294 PF06961.13 EMT52307.1 - 0.098 12.9 0.1 0.55 10.5 0.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) Proton_antipo_M PF00361.20 EMT52308.1 - 3.5e-92 308.7 23.6 3.5e-92 308.7 23.6 2.1 2 0 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 EMT52308.1 - 6e-20 71.1 2.4 1.4e-19 69.9 0.6 2.8 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_C PF01010.19 EMT52308.1 - 2.2e-05 24.2 2.6 0.00095 18.9 2.6 3.0 1 1 0 1 1 1 1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus NADH5_C PF06455.11 EMT52308.1 - 0.027 14.0 0.0 0.027 14.0 0.0 4.0 4 1 0 4 4 4 0 NADH dehydrogenase subunit 5 C-terminus Oxidored_q2 PF00420.24 EMT52309.1 - 2.5e-24 84.9 7.3 3e-24 84.7 7.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Oxidored_q3 PF00499.20 EMT52310.1 - 1.6e-39 134.9 12.9 2.2e-39 134.5 12.9 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF3649 PF12365.8 EMT52310.1 - 0.0063 16.2 0.5 0.0063 16.2 0.5 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3649) DUF4040 PF13244.6 EMT52310.1 - 0.015 15.4 10.0 0.015 15.4 10.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4040) Acyl_transf_3 PF01757.22 EMT52310.1 - 0.071 12.2 13.9 0.1 11.7 13.9 1.3 1 1 0 1 1 1 0 Acyltransferase family DUF3671 PF12420.8 EMT52310.1 - 0.66 10.1 0.1 0.66 10.1 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function TMEM138 PF14935.6 EMT52310.1 - 2.5 8.8 9.2 0.19 12.4 4.7 1.5 2 0 0 2 2 2 0 Transmembrane protein 138 Fer4 PF00037.27 EMT52311.1 - 2.1e-13 49.5 17.3 6.7e-07 28.9 4.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EMT52311.1 - 2.8e-10 40.6 11.1 4.2e-10 40.0 11.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EMT52311.1 - 3.4e-10 40.7 8.3 3.8e-05 24.5 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 EMT52311.1 - 1.4e-08 34.4 17.4 0.00045 20.2 2.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EMT52311.1 - 4.6e-07 29.9 12.0 2.9e-05 24.2 14.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EMT52311.1 - 7.7e-07 29.6 3.7 0.013 16.0 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMT52311.1 - 9.5e-07 28.8 24.8 0.00031 20.8 16.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EMT52311.1 - 1e-06 28.5 11.5 0.0011 18.9 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EMT52311.1 - 1.1e-06 28.7 17.9 4.5e-06 26.7 17.9 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EMT52311.1 - 1.7e-05 25.1 9.8 3.3e-05 24.3 9.8 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 EMT52311.1 - 0.0008 20.2 7.3 0.16 12.8 1.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EMT52311.1 - 0.00086 19.6 15.6 0.057 13.9 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 EMT52311.1 - 0.012 16.5 3.0 0.012 16.5 3.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 EMT52311.1 - 0.092 12.9 14.7 0.44 10.8 2.1 2.2 1 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EMT52311.1 - 0.99 10.0 16.5 2.2 8.9 2.3 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I DUF3654 PF12376.8 EMT52311.1 - 1.5 9.0 4.7 8.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3654) NADHdh PF00146.21 EMT52312.1 - 3.9e-124 413.8 21.2 4.5e-124 413.6 21.2 1.0 1 0 0 1 1 1 1 NADH dehydrogenase DUF4006 PF13179.6 EMT52312.1 - 0.45 10.5 2.7 0.79 9.7 0.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Complex1_49kDa PF00346.19 EMT52313.1 - 1.5e-98 329.3 0.0 1.6e-69 234.1 0.0 2.1 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EMT52313.1 - 0.0091 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase TPR_14 PF13428.6 EMT52313.1 - 0.089 13.7 0.0 0.25 12.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Complex1_30kDa PF00329.19 EMT52314.1 - 4.1e-47 159.8 0.5 6.8e-47 159.1 0.5 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Oxidored_q6 PF01058.22 EMT52315.1 - 1.6e-25 89.5 0.1 2e-25 89.1 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q4 PF00507.19 EMT52316.1 - 1.4e-37 127.8 2.5 1.4e-37 127.8 2.5 1.7 1 1 1 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Arteri_Gl PF00951.18 EMT52316.1 - 5.4 6.8 7.9 0.56 10.0 3.5 1.6 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF4132 PF13569.6 EMT52317.1 - 0.06 13.2 0.1 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4132) S_100 PF01023.19 EMT52317.1 - 4.9 6.9 6.9 0.5 10.1 0.3 2.6 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain ATP-synt_DE_N PF02823.16 EMT52318.1 - 4.6e-33 113.0 0.4 5.9e-33 112.6 0.4 1.1 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.20 EMT52318.1 - 9.8e-17 61.0 7.0 1.5e-16 60.4 7.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain ATP-synt_ab PF00006.25 EMT52319.1 - 1.4e-66 224.2 0.0 2.2e-66 223.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EMT52319.1 - 6.9e-23 80.9 0.5 1.5e-22 79.9 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 EMT52319.1 - 0.00091 19.2 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase T3SS_ATPase_C PF18269.1 EMT52319.1 - 0.0016 18.2 1.2 0.0059 16.4 1.2 1.9 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain AAA_19 PF13245.6 EMT52319.1 - 0.0066 16.8 0.8 0.031 14.6 0.8 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EMT52319.1 - 0.026 15.0 0.1 0.77 10.2 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EMT52319.1 - 0.041 13.2 1.7 0.05 13.0 0.6 1.7 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 EMT52319.1 - 0.051 13.1 0.1 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EMT52319.1 - 0.065 12.1 0.2 0.11 11.4 0.2 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 EMT52319.1 - 0.075 13.5 0.1 0.24 11.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 EMT52319.1 - 0.093 12.4 0.3 0.3 10.8 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EMT52319.1 - 0.16 12.3 0.1 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mitoc_L55 PF09776.9 EMT52319.1 - 0.2 11.4 0.1 23 4.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 NACHT PF05729.12 EMT52319.1 - 0.23 11.4 0.3 1.1 9.2 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 EMT52319.1 - 0.24 11.8 1.1 1.1 9.6 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain ATP-synt PF00231.19 EMT52320.1 - 1.5e-104 349.7 3.9 1.8e-104 349.4 3.9 1.0 1 0 0 1 1 1 1 ATP synthase ATP-synt_ab PF00006.25 EMT52321.1 - 1.1e-73 247.4 0.0 1.6e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EMT52321.1 - 1.1e-49 168.0 0.2 2.2e-49 166.9 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EMT52321.1 - 1.8e-19 70.0 5.1 3.7e-19 69.0 5.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 EMT52321.1 - 2e-05 24.6 1.1 0.00012 22.2 1.2 2.2 2 0 0 2 2 2 1 HAS barrel domain ATPase PF06745.13 EMT52321.1 - 0.00011 21.6 0.3 0.00025 20.5 0.3 1.5 1 0 0 1 1 1 1 KaiC OSCP PF00213.18 EMT52322.1 - 5.7e-55 186.1 2.1 6.3e-55 185.9 2.1 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Gp-FAR-1 PF05823.12 EMT52322.1 - 0.0009 19.6 0.3 0.0013 19.1 0.3 1.3 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GOLGA2L5 PF15070.6 EMT52322.1 - 0.014 14.1 1.4 0.019 13.7 0.5 1.6 1 1 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 WH2 PF02205.20 EMT52322.1 - 0.027 14.3 0.0 0.072 12.9 0.0 1.8 1 0 0 1 1 1 0 WH2 motif DUF1400 PF07176.11 EMT52322.1 - 0.082 13.2 1.0 0.14 12.4 0.3 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) ATP-synt_B PF00430.18 EMT52323.1 - 5.6e-33 113.8 18.5 7.8e-33 113.4 18.5 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) FliH PF02108.16 EMT52323.1 - 0.019 15.0 1.4 0.019 15.0 1.4 2.1 1 1 1 2 2 2 0 Flagellar assembly protein FliH MscL PF01741.18 EMT52323.1 - 0.046 14.0 0.6 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL DUF1103 PF06513.11 EMT52323.1 - 0.076 12.6 2.3 0.095 12.3 2.3 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) DPM3 PF08285.11 EMT52323.1 - 0.26 11.5 2.9 0.57 10.4 1.6 2.3 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FtsL PF04999.13 EMT52323.1 - 0.38 10.8 4.4 0.19 11.7 1.8 1.7 1 1 1 2 2 2 0 Cell division protein FtsL ALMT PF11744.8 EMT52323.1 - 0.41 9.4 4.5 0.51 9.1 4.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CdvA PF18822.1 EMT52323.1 - 0.48 10.2 11.8 2.5 7.9 1.1 2.3 1 1 0 2 2 2 0 CdvA-like coiled-coil domain vATP-synt_E PF01991.18 EMT52323.1 - 1.6 8.1 17.7 0.076 12.4 11.9 1.7 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit DUF2203 PF09969.9 EMT52323.1 - 1.9 9.2 7.9 2.8 8.7 7.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Phage_holin_7_1 PF16081.5 EMT52323.1 - 5.5 7.2 8.6 9.3 6.4 0.2 2.5 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family HemY_N PF07219.13 EMT52323.1 - 5.6 7.2 9.5 0.36 11.0 4.4 1.7 2 0 0 2 2 2 0 HemY protein N-terminus ATP-synt_C PF00137.21 EMT52324.1 - 1.2e-10 41.5 11.1 1.5e-10 41.3 11.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit C MctB PF11382.8 EMT52324.1 - 0.053 13.2 0.7 0.072 12.8 0.7 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Flp1_like PF16982.5 EMT52324.1 - 2.8 7.4 5.6 0.29 10.6 1.5 1.5 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain ATP-synt_A PF00119.20 EMT52325.1 - 4e-49 167.4 8.7 5e-49 167.1 8.7 1.1 1 0 0 1 1 1 1 ATP synthase A chain ATP-synt_I PF03899.15 EMT52326.1 - 2.7e-06 27.7 8.7 3.9e-06 27.2 8.7 1.2 1 0 0 1 1 1 1 ATP synthase I chain ATPase_gene1 PF09527.10 EMT52327.1 - 5e-16 58.6 7.2 5.7e-16 58.4 7.2 1.1 1 0 0 1 1 1 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter TraQ PF09679.10 EMT52327.1 - 0.17 11.9 2.6 2.2 8.3 1.1 2.0 1 1 1 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Thiolase_N PF00108.23 EMT52328.1 - 1.4e-108 362.1 0.5 1.4e-108 362.1 0.5 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMT52328.1 - 1.6e-50 169.9 3.3 1.7e-50 169.8 1.6 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMT52328.1 - 3.3e-09 36.7 3.4 2.7e-08 33.7 0.5 2.6 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EMT52328.1 - 0.065 13.1 4.5 0.13 12.1 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PPC PF04151.15 EMT52329.1 - 1.2e-05 26.3 0.3 3e-05 25.0 0.3 1.7 1 0 0 1 1 1 1 Bacterial pre-peptidase C-terminal domain Methyltransf_12 PF08242.12 EMT52331.1 - 9.6e-17 61.6 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT52331.1 - 3e-16 59.7 0.0 4.1e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT52331.1 - 6.9e-16 58.7 0.0 1.6e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT52331.1 - 1.1e-15 58.0 0.0 2.7e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT52331.1 - 4.5e-10 39.5 0.0 7.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EMT52331.1 - 1.1e-06 28.4 0.0 1.6e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 EMT52331.1 - 3.5e-06 26.5 0.0 4.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EMT52331.1 - 1.4e-05 24.5 0.0 1.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 EMT52331.1 - 0.00011 21.4 0.0 0.00013 21.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_33 PF10017.9 EMT52331.1 - 0.0017 17.6 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_4 PF02390.17 EMT52331.1 - 0.0035 16.8 0.0 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 EMT52331.1 - 0.036 13.8 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 EMT52331.1 - 0.052 13.3 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Abhydrolase_1 PF00561.20 EMT52332.1 - 2.6e-11 43.7 0.0 2.5e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMT52332.1 - 4.9e-10 40.4 0.6 6.4e-10 40.0 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMT52332.1 - 1.9e-09 37.2 0.0 2.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EMT52332.1 - 0.00033 20.9 0.0 0.00067 19.8 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 EMT52332.1 - 0.00075 19.4 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EMT52332.1 - 0.0055 16.2 0.0 0.27 10.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 EMT52332.1 - 0.11 12.7 0.1 0.41 10.8 0.1 1.9 1 1 0 1 1 1 0 TAP-like protein DLH PF01738.18 EMT52332.1 - 0.18 11.4 0.0 7.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Aminotran_1_2 PF00155.21 EMT52333.1 - 1.3e-70 238.4 0.0 1.6e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EMT52333.1 - 0.0011 18.3 0.0 0.0023 17.3 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 EMT52333.1 - 0.0016 17.3 0.0 0.035 12.8 0.0 2.1 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_3 PF00202.21 EMT52333.1 - 0.028 13.1 0.0 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III AtuA PF07287.11 EMT52333.1 - 0.055 12.2 0.1 0.083 11.6 0.1 1.2 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA Cys_Met_Meta_PP PF01053.20 EMT52333.1 - 0.18 10.3 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Radical_SAM PF04055.21 EMT52334.1 - 4.3e-18 66.2 0.2 7.8e-18 65.4 0.2 1.4 1 0 0 1 1 1 1 Radical SAM superfamily BATS PF06968.13 EMT52334.1 - 3.7e-17 62.2 0.1 3.7e-16 59.1 0.0 2.4 2 1 1 3 3 3 1 Biotin and Thiamin Synthesis associated domain Ligase_CoA PF00549.19 EMT52334.1 - 0.00042 20.2 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 2 CoA-ligase DUF5089 PF17002.5 EMT52334.1 - 0.11 12.4 0.0 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) His_biosynth PF00977.21 EMT52334.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.4 1 1 0 1 1 1 0 Histidine biosynthesis protein AAA_26 PF13500.6 EMT52335.1 - 9.3e-53 179.0 0.0 1.1e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EMT52335.1 - 2.1e-13 50.4 0.0 3.3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EMT52335.1 - 0.0029 17.1 0.0 0.006 16.1 0.0 1.5 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1611 PF07755.11 EMT52335.1 - 0.0066 15.8 0.4 0.09 12.0 0.2 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF1611_C) P-loop domain ParA PF10609.9 EMT52335.1 - 0.0068 15.9 0.3 0.11 11.9 0.2 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase MobB PF03205.14 EMT52335.1 - 0.044 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Aminotran_3 PF00202.21 EMT52336.1 - 1.1e-119 399.8 0.0 1.3e-119 399.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SLH PF00395.20 EMT52337.1 - 4.3e-34 116.3 2.4 3.2e-15 55.9 0.1 3.8 3 0 0 3 3 3 3 S-layer homology domain NAGPA PF09992.9 EMT52337.1 - 9.9e-33 113.7 5.9 6e-29 101.4 1.6 2.8 3 0 0 3 3 3 2 Phosphodiester glycosidase Big_2 PF02368.18 EMT52337.1 - 0.0056 16.5 6.1 0.027 14.4 6.1 2.3 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 2) ArabFuran-catal PF09206.11 EMT52337.1 - 0.0097 15.2 0.1 0.022 14.0 0.0 1.6 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic Invasin_D3 PF09134.10 EMT52337.1 - 6 7.3 7.0 4.4 7.7 2.9 3.0 3 0 0 3 3 3 0 Invasin, domain 3 Epimerase_2 PF02350.19 EMT52338.1 - 2.3e-120 401.6 2.5 2.6e-120 401.4 2.5 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_transf_4 PF13439.6 EMT52338.1 - 0.0034 17.4 0.2 0.02 14.9 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 EMT52338.1 - 0.01 15.9 0.1 0.023 14.8 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like UPRTase PF14681.6 EMT52339.1 - 2.6e-75 252.4 0.0 3e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EMT52339.1 - 7.6e-11 41.8 0.2 1.1e-10 41.2 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SHMT PF00464.19 EMT52340.1 - 1.9e-181 603.0 0.3 2.3e-181 602.8 0.3 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EMT52340.1 - 1.2e-12 47.7 0.0 2.2e-12 46.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EMT52340.1 - 0.00022 20.6 0.1 0.001 18.4 0.1 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EMT52340.1 - 0.0084 14.7 0.0 0.012 14.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EMT52340.1 - 0.054 12.8 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EMT52340.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase DUF436 PF04260.12 EMT52341.1 - 1.2e-78 262.6 3.8 1.4e-78 262.4 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF436) LacAB_rpiB PF02502.18 EMT52342.1 - 2.5e-60 202.5 0.0 2.9e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase EF-hand_10 PF14788.6 EMT52342.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 EF hand LMWPc PF01451.21 EMT52343.1 - 8.1e-35 120.3 0.0 9.1e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase HEAT_2 PF13646.6 EMT52343.1 - 0.014 15.7 0.0 0.022 15.2 0.0 1.2 1 0 0 1 1 1 0 HEAT repeats Mntp PF02659.15 EMT52344.1 - 1.3e-43 148.4 27.0 5.3e-41 139.9 17.6 2.0 1 1 1 2 2 2 2 Putative manganese efflux pump Sua5_yciO_yrdC PF01300.18 EMT52345.1 - 1.8e-58 197.0 0.0 2.6e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EMT52345.1 - 1.1e-34 119.8 0.0 1.8e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding PdaC PF13739.6 EMT52346.1 - 2.6e-21 76.4 0.4 4e-21 75.8 0.4 1.3 1 0 0 1 1 1 1 Deacetylase PdaC DUF3298 PF11738.8 EMT52346.1 - 3.4e-16 60.0 3.1 4.5e-16 59.6 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3298) Gmad2 PF10648.9 EMT52346.1 - 0.087 13.1 0.0 0.23 11.7 0.0 1.8 1 1 1 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination Spore_II_R PF09551.10 EMT52347.1 - 2.5e-47 160.5 0.0 5.6e-47 159.4 0.0 1.6 2 0 0 2 2 2 1 Stage II sporulation protein R (spore_II_R) DUF2407_C PF13373.6 EMT52347.1 - 2.2 8.5 4.5 0.6 10.3 1.4 1.7 2 0 0 2 2 2 0 DUF2407 C-terminal domain PrmC_N PF17827.1 EMT52348.1 - 1e-13 51.6 0.1 2.6e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 PrmC N-terminal domain MTS PF05175.14 EMT52348.1 - 1.4e-13 50.7 0.0 2.1e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EMT52348.1 - 6e-12 45.6 0.0 8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT52348.1 - 5.5e-11 43.0 0.0 9.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT52348.1 - 2.7e-06 27.9 0.0 5.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMT52348.1 - 1.5e-05 24.5 0.0 2.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EMT52348.1 - 5.7e-05 22.5 0.0 8.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain UPF0020 PF01170.18 EMT52348.1 - 9.8e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 EMT52348.1 - 0.00034 20.3 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_10 PF05971.12 EMT52348.1 - 0.00043 19.7 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_23 PF13489.6 EMT52348.1 - 0.00048 20.0 0.0 0.00075 19.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EMT52348.1 - 0.00085 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.15 EMT52348.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.12 EMT52348.1 - 0.0021 18.8 0.0 0.0036 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EMT52348.1 - 0.0062 16.5 0.0 0.0086 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EMT52348.1 - 0.0078 16.1 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMT52348.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EMT52348.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PCRF PF03462.18 EMT52349.1 - 2.9e-74 249.1 0.9 2.9e-74 249.1 0.9 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EMT52349.1 - 5e-42 142.5 1.1 5e-42 142.5 1.1 2.1 2 0 0 2 2 2 1 RF-1 domain ABC_tran_CTD PF16326.5 EMT52349.1 - 0.00014 22.0 0.1 0.00014 22.0 0.1 3.2 2 1 1 3 3 3 1 ABC transporter C-terminal domain V_ATPase_I PF01496.19 EMT52349.1 - 0.092 10.7 0.1 0.13 10.1 0.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spore_YhcN_YlaJ PF09580.10 EMT52350.1 - 2.9e-05 24.2 0.5 3.6e-05 23.9 0.5 1.2 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Ala_racemase_C PF00842.21 EMT52350.1 - 0.039 13.8 0.1 0.062 13.1 0.1 1.3 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain ZT_dimer PF16916.5 EMT52350.1 - 0.04 14.0 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter DUF4254 PF14063.6 EMT52350.1 - 0.091 12.6 0.4 1.9 8.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) TK PF00265.18 EMT52351.1 - 1.3e-48 165.2 0.0 1.5e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase UvrC_HhH_N PF08459.11 EMT52351.1 - 0.062 13.2 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal AAA_30 PF13604.6 EMT52351.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain YyzF PF14116.6 EMT52351.1 - 0.19 11.8 1.9 0.38 10.8 0.0 2.3 2 1 1 3 3 3 0 YyzF-like protein Ribosomal_L31 PF01197.18 EMT52352.1 - 2.2e-31 107.9 0.2 2.4e-31 107.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 Radical_SAM PF04055.21 EMT52353.1 - 9.7e-10 39.1 0.0 1.6e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Peptidase_M23 PF01551.22 EMT52354.1 - 2.1e-31 108.0 0.7 3.9e-31 107.1 0.7 1.5 1 0 0 1 1 1 1 Peptidase family M23 LysM PF01476.20 EMT52354.1 - 5.9e-22 77.5 0.0 3.3e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 LysM domain HTH_Tnp_1 PF01527.20 EMT52354.1 - 0.0063 16.8 0.2 5.1 7.5 0.0 3.2 3 0 0 3 3 3 1 Transposase DUF433 PF04255.14 EMT52354.1 - 0.022 14.6 0.1 8.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Phage_tail_X PF05489.12 EMT52354.1 - 0.029 14.0 0.0 0.42 10.3 0.0 2.6 3 0 0 3 3 3 0 Phage Tail Protein X DUF2703 PF10865.8 EMT52354.1 - 0.03 14.5 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) Sigma70_r4 PF04545.16 EMT52354.1 - 0.039 13.5 0.1 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 Rho_RNA_bind PF07497.12 EMT52355.1 - 1.2e-33 114.8 0.0 2.2e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 EMT52355.1 - 1.1e-18 67.7 0.0 1.7e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 EMT52355.1 - 3e-16 59.1 1.5 7.5e-16 57.8 1.5 1.7 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain NACHT PF05729.12 EMT52355.1 - 0.0016 18.4 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 EMT52355.1 - 0.002 18.6 0.1 0.02 15.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) OB_RNB PF08206.11 EMT52355.1 - 0.0036 17.0 0.0 0.0084 15.8 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease B OB domain ATPase_2 PF01637.18 EMT52355.1 - 0.0098 15.8 0.9 0.033 14.1 0.1 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Mor PF08765.11 EMT52355.1 - 0.041 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Mor transcription activator family AAA_25 PF13481.6 EMT52355.1 - 0.043 13.4 0.1 0.14 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EMT52355.1 - 0.048 13.9 0.0 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain FBPase_glpX PF03320.13 EMT52356.1 - 1.7e-145 483.7 10.4 1.9e-145 483.5 10.4 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Peripla_BP_6 PF13458.6 EMT52356.1 - 0.043 13.5 0.9 0.061 13.0 0.1 1.6 2 0 0 2 2 2 0 Periplasmic binding protein EPSP_synthase PF00275.20 EMT52357.1 - 2.7e-93 312.9 0.1 3.1e-93 312.7 0.1 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) TAL_FSA PF00923.19 EMT52358.1 - 1.9e-57 194.8 0.3 1.7e-56 191.7 0.3 2.0 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase F_bP_aldolase PF01116.20 EMT52359.1 - 8.1e-101 337.2 0.5 9e-101 337.0 0.5 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II AP_endonuc_2 PF01261.24 EMT52359.1 - 0.052 13.0 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Response_reg PF00072.24 EMT52360.1 - 1.5e-31 108.8 1.2 1.7e-31 108.7 1.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Amj PF10997.8 EMT52361.1 - 7.1e-93 310.6 11.2 8.1e-93 310.4 11.2 1.0 1 0 0 1 1 1 1 Alternate to MurJ DAD PF02109.16 EMT52361.1 - 0.077 13.3 0.2 0.16 12.3 0.2 1.5 1 0 0 1 1 1 0 DAD family CTP_synth_N PF06418.14 EMT52362.1 - 1.9e-131 437.2 0.5 2.5e-131 436.8 0.5 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EMT52362.1 - 2.7e-56 190.4 0.0 4.4e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EMT52362.1 - 7.8e-08 32.3 0.2 3.4e-06 27.0 0.0 2.8 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.23 EMT52362.1 - 0.0019 18.2 0.0 0.006 16.6 0.0 1.9 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain HARE-HTH PF05066.13 EMT52363.1 - 8.4e-08 32.5 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain MM_CoA_mutase PF01642.22 EMT52364.1 - 2e-143 478.6 0.4 3.7e-143 477.8 0.2 1.5 2 0 0 2 2 2 1 Methylmalonyl-CoA mutase MeaB PF03308.16 EMT52364.1 - 5.6e-41 140.3 0.0 1e-40 139.5 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB B12-binding PF02310.19 EMT52364.1 - 7.8e-13 48.5 0.1 2.2e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 B12 binding domain cobW PF02492.19 EMT52364.1 - 6.5e-08 32.4 0.0 3e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 EMT52364.1 - 0.011 15.4 0.1 0.031 13.9 0.1 1.8 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 EMT52364.1 - 0.035 14.7 1.3 0.17 12.4 0.1 2.6 3 0 0 3 3 3 0 AAA domain Hpr_kinase_C PF07475.12 EMT52364.1 - 0.079 12.5 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Fib_alpha PF08702.10 EMT52364.1 - 3 8.0 8.1 0.28 11.4 0.1 3.0 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family TetR_N PF00440.23 EMT52365.1 - 4.3e-14 52.0 0.2 8.3e-14 51.1 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EMT52365.1 - 2e-10 41.0 0.3 4.4e-10 39.8 0.1 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 EMT52365.1 - 0.00068 19.8 0.0 0.0018 18.4 0.0 1.8 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase ER PF01133.17 EMT52365.1 - 0.0027 17.7 0.2 2.1 8.4 0.1 2.6 1 1 1 2 2 2 2 Enhancer of rudimentary TetR PF13972.6 EMT52365.1 - 0.0068 16.1 0.2 0.012 15.3 0.1 1.6 2 0 0 2 2 2 1 Bacterial transcriptional repressor MeaB PF03308.16 EMT52366.1 - 1.3e-99 332.5 0.2 1.5e-99 332.3 0.2 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 EMT52366.1 - 6.2e-07 29.2 0.9 8.4e-06 25.5 0.9 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EMT52366.1 - 0.00059 19.8 0.0 0.2 11.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EMT52366.1 - 0.0016 18.0 0.0 0.83 9.2 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EMT52366.1 - 0.0018 18.7 2.7 0.013 15.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.17 EMT52366.1 - 0.0025 17.6 0.1 0.056 13.2 0.0 2.3 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EMT52366.1 - 0.0026 18.3 0.1 0.0056 17.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 EMT52366.1 - 0.01 15.9 0.1 0.041 14.0 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EMT52366.1 - 0.01 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 EMT52366.1 - 0.014 15.3 0.1 0.026 14.4 0.1 1.6 1 1 0 1 1 1 0 NTPase AAA_22 PF13401.6 EMT52366.1 - 0.029 14.7 0.2 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EMT52366.1 - 0.029 14.3 0.1 0.15 11.9 0.0 2.1 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 EMT52366.1 - 0.034 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.7 EMT52366.1 - 0.042 12.8 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.22 EMT52366.1 - 0.11 12.1 0.0 0.48 10.0 0.0 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 EMT52366.1 - 0.12 12.5 0.2 0.32 11.0 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain Mac PF12464.8 EMT52366.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Maltose acetyltransferase AAA_23 PF13476.6 EMT52366.1 - 0.17 12.3 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Acyl-CoA_dh_1 PF00441.24 EMT52367.1 - 8.7e-54 181.8 1.9 1.4e-53 181.2 1.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMT52367.1 - 5.5e-43 146.2 0.3 1.1e-42 145.3 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EMT52367.1 - 2.6e-29 102.2 0.5 4.4e-29 101.5 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMT52367.1 - 7.4e-28 96.6 0.1 1.6e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EMT52368.1 - 4.7e-55 185.9 3.6 6.9e-55 185.4 3.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMT52368.1 - 2.9e-39 134.2 0.2 7.1e-39 133.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EMT52368.1 - 1.5e-29 102.9 2.4 2.4e-29 102.3 2.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMT52368.1 - 1.1e-28 99.2 0.0 2.1e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EMT52368.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal 3HCDH_N PF02737.18 EMT52369.1 - 1.1e-68 230.7 2.2 1.4e-68 230.3 2.2 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EMT52369.1 - 1e-37 128.6 0.0 6.1e-37 126.1 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EMT52369.1 - 0.00013 22.0 0.3 0.00019 21.4 0.3 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 EMT52369.1 - 0.00045 20.4 1.9 0.0014 18.8 1.9 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 EMT52369.1 - 0.0059 16.2 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 EMT52369.1 - 0.013 16.0 0.1 0.019 15.5 0.1 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 EMT52369.1 - 0.018 14.4 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EMT52369.1 - 0.15 12.3 0.9 0.29 11.4 0.9 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EMT52369.1 - 0.22 12.1 3.6 0.68 10.6 3.0 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EMT52369.1 - 0.25 11.4 1.8 0.52 10.4 0.3 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EMT52369.1 - 0.4 10.0 2.3 0.98 8.7 2.1 1.7 1 1 0 1 1 1 0 ThiF family Thiolase_N PF00108.23 EMT52370.1 - 3.2e-101 338.1 0.4 4.1e-101 337.7 0.4 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMT52370.1 - 1.8e-44 150.4 3.9 3.4e-44 149.4 1.2 2.3 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMT52370.1 - 0.0054 16.3 0.7 0.0054 16.3 0.7 2.9 3 1 1 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EMT52370.1 - 0.024 14.5 1.8 1.7 8.5 0.2 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1153 PF06627.11 EMT52370.1 - 0.03 14.4 0.6 3.7 7.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) Sigma70_r4_2 PF08281.12 EMT52372.1 - 6.4e-16 57.8 0.3 1.3e-15 56.8 0.3 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT52372.1 - 1.5e-15 56.4 0.9 1.3e-14 53.4 0.3 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT52372.1 - 1.4e-13 50.4 0.7 2.2e-13 49.8 0.1 1.6 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 EMT52372.1 - 6.8e-06 26.1 0.1 1.7e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 ECF sigma factor UPF0122 PF04297.14 EMT52372.1 - 8.4e-05 22.7 0.2 0.00031 20.9 0.0 1.9 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_10 PF04967.12 EMT52372.1 - 0.0021 17.8 0.1 0.0045 16.7 0.1 1.6 1 0 0 1 1 1 1 HTH DNA binding domain Phage_antitermQ PF06530.12 EMT52372.1 - 0.0068 16.3 0.3 0.02 14.8 0.1 1.8 2 0 0 2 2 2 1 Phage antitermination protein Q HTH_AsnC-type PF13404.6 EMT52372.1 - 0.0077 16.0 0.5 0.33 10.8 0.1 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain GerE PF00196.19 EMT52372.1 - 0.019 14.5 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF134 PF02001.16 EMT52372.1 - 0.019 15.5 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_23 PF13384.6 EMT52372.1 - 0.071 12.9 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.12 EMT52372.1 - 0.11 12.5 0.8 0.28 11.1 0.1 2.0 2 0 0 2 2 2 0 HTH domain Mis12 PF05859.12 EMT52372.1 - 0.13 12.3 0.8 0.45 10.6 0.1 2.0 2 1 0 2 2 2 0 Mis12 protein PEP-utilisers_N PF05524.13 EMT52372.1 - 0.34 11.1 1.7 14 5.9 0.0 2.3 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal HTH_24 PF13412.6 EMT52372.1 - 0.52 9.9 0.0 0.52 9.9 0.0 2.7 5 0 0 5 5 5 0 Winged helix-turn-helix DNA-binding CCG PF02754.16 EMT52373.1 - 1.2e-26 92.7 2.3 2.3e-17 63.0 0.4 3.1 3 0 0 3 3 3 2 Cysteine-rich domain Fer4_8 PF13183.6 EMT52373.1 - 2.5e-12 47.0 2.6 2.5e-12 47.0 2.6 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EMT52373.1 - 3.1e-07 31.2 5.0 0.0026 18.6 0.5 2.7 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EMT52373.1 - 5.9e-07 29.5 9.9 5.9e-07 29.5 9.9 2.8 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EMT52373.1 - 1.5e-06 28.7 3.9 0.023 15.2 0.2 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EMT52373.1 - 8.5e-06 26.3 8.4 2e-05 25.1 5.5 2.9 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EMT52373.1 - 1.4e-05 25.2 10.3 1.4e-05 25.2 10.3 2.7 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EMT52373.1 - 7.7e-05 22.7 4.1 0.12 12.5 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 EMT52373.1 - 0.00016 22.4 6.1 0.017 15.9 0.2 3.9 4 0 0 4 4 4 1 4Fe-4S dicluster domain Fer4 PF00037.27 EMT52373.1 - 0.0063 16.3 2.1 0.0063 16.3 2.1 2.7 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 EMT52373.1 - 0.0098 15.9 2.3 0.0098 15.9 2.3 2.8 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EMT52373.1 - 0.013 16.0 16.1 0.06 13.9 1.2 2.9 3 0 0 3 3 2 0 4Fe-4S binding domain DUF1467 PF07330.12 EMT52373.1 - 0.027 14.4 1.1 0.09 12.7 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) DDE_Tnp_1_6 PF13751.6 EMT52373.1 - 0.035 14.3 0.5 0.84 9.9 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain Fer4_18 PF13746.6 EMT52373.1 - 1.1 9.4 5.0 13 6.0 0.3 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 EMT52373.1 - 1.5 9.1 17.6 0.23 11.6 1.8 2.8 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 EMT52373.1 - 1.5 9.4 8.2 5.4 7.6 2.6 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I DUF373 PF04123.13 EMT52373.1 - 2.6 7.4 6.9 4.1 6.8 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Bac_export_2 PF01312.19 EMT52373.1 - 5.1 6.2 6.6 3.8 6.6 1.1 2.4 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family LAM_C PF12544.8 EMT52374.1 - 3e-50 169.6 0.1 5.3e-50 168.8 0.1 1.4 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 EMT52374.1 - 1.9e-06 28.4 0.2 7.9e-06 26.3 0.1 2.1 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 EMT52374.1 - 3.2e-05 24.2 0.6 7.6e-05 23.0 0.0 2.0 3 0 0 3 3 3 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EMT52374.1 - 0.00014 21.9 0.0 0.0022 18.1 0.0 2.4 1 1 1 2 2 2 1 4Fe-4S single cluster domain Sigma54_activat PF00158.26 EMT52375.1 - 4.9e-63 211.8 0.0 7.6e-63 211.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT52375.1 - 2.2e-19 69.9 0.0 1.2e-18 67.6 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 EMT52375.1 - 2e-14 53.1 0.5 2e-14 53.1 0.5 2.2 3 0 0 3 3 2 1 Bacterial regulatory protein, Fis family PAS PF00989.25 EMT52375.1 - 4e-10 39.7 0.0 1.2e-09 38.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EMT52375.1 - 9e-09 35.6 0.0 3.6e-08 33.6 0.0 2.1 2 0 0 2 2 1 1 PAS fold AAA_5 PF07728.14 EMT52375.1 - 4.6e-07 29.9 0.0 1.4e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMT52375.1 - 0.00015 21.2 0.0 0.0041 16.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PAS_9 PF13426.7 EMT52375.1 - 0.0005 20.3 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 PAS domain MCM PF00493.23 EMT52375.1 - 0.0025 17.0 0.0 0.0061 15.7 0.0 1.6 1 1 0 1 1 1 1 MCM P-loop domain AAA PF00004.29 EMT52375.1 - 0.0048 17.3 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_30 PF13556.6 EMT52375.1 - 0.005 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain AAA_16 PF13191.6 EMT52375.1 - 0.007 16.8 0.1 0.014 15.8 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EMT52375.1 - 0.047 13.2 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EMT52375.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Bac_DnaA PF00308.18 EMT52375.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein DUF815 PF05673.13 EMT52375.1 - 0.15 11.2 0.0 0.41 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TraL PF07178.11 EMT52376.1 - 0.011 16.1 1.3 0.011 16.1 1.3 2.4 1 1 0 2 2 2 0 TraL protein DUF3021 PF11457.8 EMT52376.1 - 0.44 10.9 11.4 0.55 10.6 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DUF3810 PF12725.7 EMT52376.1 - 2.5 7.4 6.6 0.63 9.3 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Vma12 PF11712.8 EMT52376.1 - 2.9 8.0 5.1 7.1 6.7 5.1 1.8 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase E1-E2_ATPase PF00122.20 EMT52376.1 - 7.3 6.1 8.8 0.49 9.9 3.1 1.8 1 1 1 2 2 2 0 E1-E2 ATPase DUF1934 PF09148.10 EMT52377.1 - 1.2e-24 86.7 1.2 1.4e-24 86.5 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1934) PAW PF04721.17 EMT52377.1 - 0.011 15.6 2.5 0.015 15.1 2.5 1.3 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW CreA PF05981.12 EMT52377.1 - 0.061 13.3 0.0 0.087 12.8 0.0 1.3 1 1 0 1 1 1 0 CreA protein MFS_1 PF07690.16 EMT52378.1 - 1.7e-29 102.9 71.6 1.1e-25 90.3 42.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT52378.1 - 3e-16 58.9 27.3 3.7e-16 58.6 27.3 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 EMT52378.1 - 1.8e-05 23.5 38.9 0.00014 20.6 8.0 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein DUF3099 PF11298.8 EMT52378.1 - 1.6 9.0 10.6 8.2 6.6 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) Arginase PF00491.21 EMT52379.1 - 1.1e-77 261.3 0.0 1.2e-77 261.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EMT52379.1 - 0.074 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Spermine_synth PF01564.17 EMT52380.1 - 2e-62 210.0 0.0 2.7e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EMT52380.1 - 1.9e-19 69.3 1.4 1.1e-18 66.8 0.9 2.3 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EMT52380.1 - 0.042 14.5 0.0 0.087 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DRE2_N PF16803.5 EMT52380.1 - 0.11 12.7 0.0 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus Transgly PF00912.22 EMT52381.1 - 1.1e-65 220.4 0.5 2e-65 219.5 0.5 1.4 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 EMT52381.1 - 6.6e-34 117.5 0.5 5.5e-33 114.5 0.5 2.1 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain MarR PF01047.22 EMT52382.1 - 0.17 11.8 0.0 0.28 11.2 0.0 1.5 1 1 0 1 1 1 0 MarR family YwhD PF08741.10 EMT52383.1 - 1.1e-76 256.0 0.8 1.3e-76 255.8 0.8 1.0 1 0 0 1 1 1 1 YwhD family SieB PF14163.6 EMT52383.1 - 0.039 13.4 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF2170 PF09938.9 EMT52383.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) DUF2058 PF09831.9 EMT52384.1 - 0.048 13.8 0.1 0.061 13.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) LCAT PF02450.15 EMT52386.1 - 1.8e-77 261.2 0.0 2.5e-77 260.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 EMT52386.1 - 6.8e-10 39.1 0.1 4.2e-09 36.5 0.1 2.0 1 1 0 1 1 1 1 PGAP1-like protein PPC PF04151.15 EMT52386.1 - 4.6e-09 37.2 1.0 3.4e-07 31.3 0.1 3.1 3 0 0 3 3 2 1 Bacterial pre-peptidase C-terminal domain Abhydrolase_1 PF00561.20 EMT52386.1 - 6.6e-05 22.7 0.0 0.00029 20.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 EMT52386.1 - 7.2e-05 22.2 0.1 0.0046 16.3 0.1 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 EMT52386.1 - 0.00099 18.7 0.0 0.0027 17.3 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.7 EMT52386.1 - 0.0012 19.5 0.0 0.0033 18.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMT52386.1 - 0.0015 17.9 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 EMT52386.1 - 0.0031 17.4 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF900 PF05990.12 EMT52386.1 - 0.0062 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 EMT52386.1 - 0.0064 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Flagellin_D3 PF08884.11 EMT52386.1 - 0.016 15.6 0.2 2.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Flagellin D3 domain CBM_4_9 PF02018.17 EMT52387.1 - 0.00072 19.8 0.7 0.029 14.7 0.0 3.9 4 0 0 4 4 4 1 Carbohydrate binding domain CARDB PF07705.11 EMT52387.1 - 0.0018 18.5 0.3 0.012 15.9 0.0 2.6 2 0 0 2 2 2 1 CARDB N_BRCA1_IG PF16158.5 EMT52387.1 - 0.0019 18.9 0.0 0.019 15.7 0.0 2.5 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene A2M_BRD PF07703.14 EMT52387.1 - 0.031 14.6 0.2 8.3 6.8 0.0 3.7 4 0 0 4 4 4 0 Alpha-2-macroglobulin bait region domain SLH PF00395.20 EMT52388.1 - 6.9e-09 35.6 0.0 1.4e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 S-layer homology domain DUF3302 PF11742.8 EMT52388.1 - 0.082 13.0 0.1 0.24 11.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) Thioredoxin PF00085.20 EMT52389.1 - 5.1e-12 45.7 0.0 6.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMT52389.1 - 1.9e-05 25.1 0.1 0.0001 22.7 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 EMT52389.1 - 0.00059 20.0 0.2 0.26 11.5 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 EMT52389.1 - 0.00076 19.5 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.6 EMT52389.1 - 0.00096 19.0 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Cyt_bd_oxida_II PF02322.15 EMT52389.1 - 0.048 13.0 0.2 0.06 12.7 0.2 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DNA_ligase_OB PF03120.16 EMT52389.1 - 0.065 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain AhpC-TSA PF00578.21 EMT52389.1 - 0.087 12.7 0.2 0.32 10.9 0.0 1.8 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_8 PF13905.6 EMT52389.1 - 0.099 13.0 0.0 0.44 10.9 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like PBP_N PF17093.5 EMT52389.1 - 0.17 12.1 0.3 0.23 11.7 0.3 1.2 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus DUF1082 PF06449.11 EMT52390.1 - 0.18 11.7 0.1 0.48 10.3 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) HD PF01966.22 EMT52391.1 - 1.1e-16 61.2 0.4 2e-16 60.3 0.4 1.5 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 EMT52391.1 - 0.0013 18.6 0.3 0.002 17.9 0.3 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ACR_tran PF00873.19 EMT52392.1 - 1.7e-181 605.3 10.5 2e-181 605.2 10.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EMT52392.1 - 1.9e-09 37.0 10.6 1.9e-09 37.0 10.6 2.5 2 0 0 2 2 2 1 MMPL family SecD_SecF PF02355.16 EMT52392.1 - 6.5e-06 25.6 29.3 1.5e-05 24.5 6.5 2.9 3 0 0 3 3 3 2 Protein export membrane protein HlyD_D23 PF16576.5 EMT52393.1 - 2.4e-15 56.3 7.5 1.7e-13 50.3 7.0 2.6 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EMT52393.1 - 4.4e-14 53.1 5.0 1.9e-11 44.6 0.2 3.8 2 2 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EMT52393.1 - 5.1e-12 45.4 1.1 6e-11 42.0 0.1 3.3 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 EMT52393.1 - 3.4e-05 23.6 0.1 0.0038 17.0 0.0 3.0 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD PF00529.20 EMT52393.1 - 0.013 15.4 0.3 0.013 15.4 0.3 3.3 2 2 1 3 3 3 0 HlyD membrane-fusion protein of T1SS OEP PF02321.18 EMT52393.1 - 0.036 13.9 9.7 0.12 12.2 9.7 1.9 1 1 0 1 1 1 0 Outer membrane efflux protein QRPTase_N PF02749.16 EMT52393.1 - 0.058 13.5 0.1 0.21 11.6 0.1 2.0 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain RnfC_N PF13375.6 EMT52393.1 - 0.17 11.9 2.3 0.45 10.5 0.1 2.9 3 1 0 3 3 3 0 RnfC Barrel sandwich hybrid domain SecD-TM1 PF13721.6 EMT52393.1 - 2.9 8.4 8.6 1.1 9.8 0.6 3.0 2 1 1 3 3 3 0 SecD export protein N-terminal TM region TetR_N PF00440.23 EMT52394.1 - 2.2e-15 56.2 0.1 2.2e-15 56.2 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 EMT52394.1 - 8.3e-05 22.6 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain HxlR PF01638.17 EMT52394.1 - 0.0073 16.1 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 HxlR-like helix-turn-helix TetR_C_11 PF16859.5 EMT52394.1 - 0.039 14.3 0.1 0.11 12.8 0.0 1.8 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 EMT52394.1 - 0.039 13.8 0.1 0.086 12.7 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 EMT52394.1 - 0.063 13.4 0.0 0.21 11.8 0.0 1.9 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase LacI PF00356.21 EMT52394.1 - 0.085 12.7 0.0 3 7.7 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF910 PF06014.11 EMT52394.1 - 0.091 12.8 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF910) PseudoU_synth_2 PF00849.22 EMT52395.1 - 9.5e-32 110.3 0.1 1.4e-31 109.8 0.1 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase RhlB PF12300.8 EMT52395.1 - 0.17 12.0 3.0 0.76 9.9 0.3 2.6 3 0 0 3 3 3 0 ATP-dependent RNA helicase RhlB Peptidase_M29 PF02073.15 EMT52396.1 - 1.3e-56 192.1 0.0 1.7e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) Rhodanese PF00581.20 EMT52397.1 - 5e-11 43.1 0.0 4.6e-10 40.0 0.0 2.4 2 1 0 2 2 2 1 Rhodanese-like domain AAA_18 PF13238.6 EMT52397.1 - 2.9e-05 24.6 0.0 9e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 EMT52397.1 - 0.0036 17.5 0.0 0.017 15.3 0.0 2.1 1 1 1 2 2 2 1 Cytidylate kinase-like family AAA_16 PF13191.6 EMT52397.1 - 0.0059 17.0 0.3 0.024 15.0 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EMT52397.1 - 0.0087 16.6 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMT52397.1 - 0.035 14.4 0.0 0.11 12.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain DUF736 PF05284.12 EMT52397.1 - 0.064 13.2 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF736) AAA_33 PF13671.6 EMT52397.1 - 0.067 13.4 0.1 0.23 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMT52397.1 - 0.099 12.9 0.0 0.89 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AIRS_C PF02769.22 EMT52398.1 - 1.8e-29 102.9 0.1 3.1e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EMT52398.1 - 3.8e-19 69.1 0.2 9.4e-19 67.9 0.2 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Chlorophyllase PF07224.11 EMT52399.1 - 0.028 13.4 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase MFS_1 PF07690.16 EMT52400.1 - 6.1e-49 166.8 51.5 2.9e-31 108.7 23.8 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT52400.1 - 1.6e-11 43.8 27.1 3.7e-06 26.1 9.3 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EMT52400.1 - 2.6e-05 23.3 26.3 0.0012 17.8 25.9 2.5 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 EMT52400.1 - 4.1e-05 22.2 8.9 0.0002 19.9 3.0 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector PUCC PF03209.15 EMT52400.1 - 0.00041 19.5 10.2 0.0019 17.3 9.9 1.9 1 1 0 1 1 1 1 PUCC protein OATP PF03137.20 EMT52400.1 - 1.1 7.4 12.1 0.091 11.0 2.1 3.2 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF4855 PF16147.5 EMT52404.1 - 2e-94 316.2 6.2 2.8e-94 315.7 6.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4855) SLH PF00395.20 EMT52404.1 - 1.3e-27 95.5 0.1 3.3e-09 36.6 0.0 3.6 3 0 0 3 3 3 3 S-layer homology domain HisKA PF00512.25 EMT52404.1 - 0.044 13.8 0.0 0.69 10.0 0.0 2.3 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Macoilin PF09726.9 EMT52404.1 - 2.9 6.3 13.5 3.9 5.9 13.5 1.1 1 0 0 1 1 1 0 Macoilin family UPF0020 PF01170.18 EMT52405.1 - 1.9e-60 204.0 0.0 2.4e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 EMT52405.1 - 3.8e-13 49.8 0.0 6.2e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 THUMP domain MTS PF05175.14 EMT52405.1 - 7.4e-07 28.9 0.0 5.3e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EMT52405.1 - 3.2e-06 27.0 0.0 0.00013 21.8 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT52405.1 - 3.5e-06 27.6 0.0 1.1e-05 26.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EMT52405.1 - 0.0019 17.7 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.8 EMT52405.1 - 0.018 14.5 0.0 5.7 6.3 0.0 3.0 2 1 1 3 3 3 0 RRNA methyltransferase AviRa N6_N4_Mtase PF01555.18 EMT52405.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Methyltransf_11 PF08241.12 EMT52405.1 - 0.027 15.1 0.0 0.066 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TPR_7 PF13176.6 EMT52405.1 - 0.033 14.2 0.1 0.082 13.0 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat N6_Mtase PF02384.16 EMT52405.1 - 0.042 13.1 0.0 0.11 11.7 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase CheR PF01739.18 EMT52405.1 - 0.11 11.9 0.0 9.3 5.7 0.0 2.5 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Cons_hypoth95 PF03602.15 EMT52405.1 - 0.15 11.7 0.0 15 5.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical protein 95 CCG PF02754.16 EMT52406.1 - 5.6e-38 129.0 5.0 1.9e-18 66.4 0.1 2.7 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 EMT52406.1 - 6.8e-14 52.1 5.3 2.2e-13 50.4 5.3 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EMT52406.1 - 3.3e-12 46.8 7.7 3.8e-12 46.6 5.7 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EMT52406.1 - 1.2e-10 41.8 6.9 3.7e-10 40.2 6.9 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EMT52406.1 - 1.7e-07 30.9 10.9 0.00092 19.2 2.5 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EMT52406.1 - 5.7e-07 29.6 6.9 2.4e-06 27.6 7.2 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EMT52406.1 - 7.4e-07 29.2 6.6 0.0013 18.8 0.9 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 EMT52406.1 - 2.1e-06 27.3 13.8 0.00093 18.9 2.6 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 EMT52406.1 - 1e-05 25.3 14.0 0.00035 20.5 2.9 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EMT52406.1 - 1e-05 25.6 11.0 0.0062 16.9 1.9 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 EMT52406.1 - 0.00011 23.0 8.7 0.00013 22.8 6.7 2.2 2 1 0 2 2 2 1 4Fe-4S double cluster binding domain AP_endonuc_2 PF01261.24 EMT52406.1 - 0.0063 16.0 0.0 0.024 14.1 0.1 1.9 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Fer4_18 PF13746.6 EMT52406.1 - 0.0096 16.1 1.0 4.2 7.6 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 EMT52406.1 - 0.02 15.0 9.6 0.28 11.3 9.6 2.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EMT52406.1 - 0.021 15.7 18.7 0.64 11.1 5.5 3.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EMT52406.1 - 0.53 11.2 11.2 1.7 9.6 1.5 3.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EMT52406.1 - 7.3 7.2 7.6 16 6.1 0.5 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I FAD-oxidase_C PF02913.19 EMT52407.1 - 1.3e-73 247.7 0.5 1.7e-73 247.3 0.5 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMT52407.1 - 1.2e-44 151.4 2.1 4.3e-44 149.6 0.2 2.5 3 0 0 3 3 3 1 FAD binding domain SPAR_C PF11881.8 EMT52407.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of SPAR protein GA-like PF17573.2 EMT52407.1 - 3.2 7.7 5.2 2.3 8.2 0.2 2.9 2 1 0 2 2 2 0 GA-like domain FCD PF07729.12 EMT52408.1 - 3.4e-25 88.9 9.1 5.8e-25 88.1 9.1 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EMT52408.1 - 5.3e-21 74.0 0.1 1.2e-20 72.9 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 EMT52408.1 - 2e-05 24.2 0.1 4.5e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 EMT52408.1 - 0.00046 20.0 0.0 0.0029 17.4 0.0 2.3 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 EMT52408.1 - 0.001 19.0 0.0 0.0031 17.4 0.0 1.8 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 EMT52408.1 - 0.0016 18.3 0.1 0.0046 16.8 0.1 1.7 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 EMT52408.1 - 0.0059 16.9 0.4 0.019 15.3 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator HTH_5 PF01022.20 EMT52408.1 - 0.013 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 EMT52408.1 - 0.017 15.3 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 EMT52408.1 - 0.033 14.0 0.0 0.092 12.6 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain TBPIP PF07106.13 EMT52408.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain BLACT_WH PF17778.1 EMT52408.1 - 0.18 11.8 0.8 0.7 9.9 0.3 2.2 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain Fapy_DNA_glyco PF01149.24 EMT52409.1 - 8.1e-22 78.0 0.1 1.2e-21 77.5 0.1 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EMT52409.1 - 1e-19 70.3 0.0 1.6e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EMT52409.1 - 1.4e-05 24.1 0.0 4.1e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) zf-FPG_IleRS PF06827.14 EMT52409.1 - 6.8e-05 22.6 4.7 0.00016 21.5 4.7 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS FecR PF04773.13 EMT52409.1 - 0.026 15.2 0.0 0.038 14.6 0.0 1.3 1 0 0 1 1 1 0 FecR protein Acetyltransf_1 PF00583.25 EMT52410.1 - 1.8e-12 47.5 0.1 4.3e-11 43.1 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT52410.1 - 6.1e-11 42.4 0.1 2.2e-10 40.6 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT52410.1 - 2.5e-10 40.7 0.2 5.3e-10 39.6 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT52410.1 - 2.1e-09 37.5 0.1 3.7e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT52410.1 - 4.3e-06 26.6 0.1 1.5e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 EMT52410.1 - 0.0014 18.7 0.1 0.0043 17.1 0.1 1.8 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 EMT52410.1 - 0.062 13.0 0.0 0.85 9.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT52410.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1232 PF06803.12 EMT52411.1 - 2.2e-11 43.3 5.0 2.2e-11 43.3 5.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1232) TPK_catalytic PF04263.16 EMT52412.1 - 2.9e-19 69.3 0.0 4.3e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EMT52412.1 - 3.9e-16 58.5 0.1 1.2e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain UDG PF03167.19 EMT52414.1 - 1.8e-27 96.3 0.0 2.6e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Cu_amine_oxidN1 PF07833.11 EMT52415.1 - 2e-07 31.4 0.0 3.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Copper amine oxidase N-terminal domain PepSY PF03413.19 EMT52415.1 - 0.059 13.9 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Sigma54_activat PF00158.26 EMT52416.1 - 1.8e-69 232.7 0.0 2.8e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT52416.1 - 2e-16 60.3 0.0 5.7e-16 58.9 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 EMT52416.1 - 2.6e-06 27.1 0.0 9.4e-06 25.3 0.0 2.1 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Mg_chelatase PF01078.21 EMT52416.1 - 1.8e-05 24.2 0.0 0.0023 17.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 EMT52416.1 - 5.2e-05 23.7 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMT52416.1 - 6e-05 23.1 0.0 0.00025 21.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_7 PF02796.15 EMT52416.1 - 0.0004 20.4 0.0 0.0014 18.6 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase GAF_2 PF13185.6 EMT52416.1 - 0.00099 19.4 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 GAF domain HTH_50 PF18024.1 EMT52416.1 - 0.0011 18.6 0.1 0.0054 16.3 0.1 2.2 1 1 0 1 1 1 1 Helix-turn-helix domain AAA_16 PF13191.6 EMT52416.1 - 0.086 13.2 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain HTH_25 PF13413.6 EMT52416.1 - 0.087 12.7 0.5 0.84 9.5 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 EMT52416.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain NACHT PF05729.12 EMT52416.1 - 0.14 12.1 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 EMT52416.1 - 0.17 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Cys_Met_Meta_PP PF01053.20 EMT52417.1 - 5.7e-147 489.2 0.0 6.4e-147 489.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EMT52417.1 - 2.8e-11 43.2 0.1 4.2e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMT52417.1 - 3.4e-09 36.1 0.0 5.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMT52417.1 - 3.1e-08 33.3 0.1 7.3e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EMT52417.1 - 1.7e-06 27.6 0.1 6.4e-06 25.7 0.1 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 EMT52417.1 - 6.8e-06 25.2 0.0 8.5e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 EMT52417.1 - 6.9e-06 24.8 0.0 1.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.13 EMT52417.1 - 1.7e-05 24.0 0.1 8.1e-05 21.8 0.1 1.8 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Cas3_C PF18395.1 EMT52417.1 - 0.15 12.5 0.0 5.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Cas3 C-terminal domain MafB19-deam PF14437.6 EMT52417.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 MafB19-like deaminase TFA2_Winged_2 PF18121.1 EMT52417.1 - 0.19 11.5 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 GMC_oxred_C PF05199.13 EMT52419.1 - 3.1e-19 69.9 0.0 5.2e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMT52419.1 - 1.8e-09 37.4 0.0 8.7e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMT52419.1 - 0.00033 19.8 0.7 0.39 9.8 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 EMT52419.1 - 0.013 15.1 0.0 0.052 13.1 0.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMT52419.1 - 0.034 13.4 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMT52419.1 - 0.16 11.2 2.0 0.21 10.8 0.6 1.9 2 0 0 2 2 2 0 FAD binding domain Gluconate_2-dh3 PF13618.6 EMT52420.1 - 1e-35 122.9 0.1 1.3e-35 122.5 0.1 1.2 1 0 0 1 1 1 1 Gluconate 2-dehydrogenase subunit 3 Metal_resist PF13801.6 EMT52420.1 - 0.074 13.2 0.5 0.26 11.5 0.3 1.8 2 0 0 2 2 2 0 Heavy-metal resistance TAT_signal PF10518.9 EMT52420.1 - 0.21 11.5 1.0 0.47 10.4 1.0 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Abhydrolase_6 PF12697.7 EMT52422.1 - 1.3e-18 68.5 0.3 1.5e-18 68.2 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMT52422.1 - 1.8e-17 63.9 0.0 6.2e-16 58.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMT52422.1 - 3.3e-09 36.4 0.0 4.3e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EMT52422.1 - 0.0072 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family CbiQ PF02361.16 EMT52423.1 - 1.4e-27 96.7 6.9 1.4e-27 96.7 6.9 1.4 2 0 0 2 2 2 1 Cobalt transport protein GRAS PF03514.14 EMT52423.1 - 0.064 12.2 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 GRAS domain family ABC_tran PF00005.27 EMT52424.1 - 1.6e-28 99.9 0.0 2.5e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT52424.1 - 6.1e-13 49.2 0.9 6.5e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT52424.1 - 2.9e-05 23.6 1.0 0.00052 19.5 1.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EMT52424.1 - 0.00098 19.4 0.3 0.0057 16.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EMT52424.1 - 0.0019 18.8 0.0 0.0025 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMT52424.1 - 0.0022 17.8 0.2 0.022 14.5 0.2 1.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 EMT52424.1 - 0.0025 18.2 0.0 0.0042 17.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EMT52424.1 - 0.009 15.8 0.5 0.11 12.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMT52424.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT52424.1 - 0.01 16.1 0.5 0.042 14.1 0.5 1.9 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EMT52424.1 - 0.017 13.8 0.0 0.65 8.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMT52424.1 - 0.023 14.4 0.7 0.08 12.7 0.7 1.8 1 1 0 1 1 1 0 AAA domain HAD PF12710.7 EMT52424.1 - 0.031 14.7 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase T2SSE PF00437.20 EMT52424.1 - 0.031 13.3 0.1 0.063 12.3 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 EMT52424.1 - 0.041 13.2 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 EMT52424.1 - 0.046 13.9 0.4 0.11 12.7 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMT52424.1 - 0.046 14.1 0.3 0.15 12.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EMT52424.1 - 0.069 13.1 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 EMT52424.1 - 0.093 11.9 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit ATPase PF06745.13 EMT52424.1 - 0.1 12.0 0.5 1 8.7 0.1 2.1 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 EMT52424.1 - 0.12 11.5 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 EMT52425.1 - 4.9e-27 95.1 0.0 7.8e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT52425.1 - 7.3e-15 55.5 1.4 3.8e-09 36.8 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT52425.1 - 1.7e-05 24.4 0.1 8.4e-05 22.1 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EMT52425.1 - 0.0012 19.1 0.1 0.0099 16.1 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EMT52425.1 - 0.0034 17.9 0.0 0.0044 17.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EMT52425.1 - 0.0064 15.3 0.2 0.49 9.1 0.1 3.0 3 1 1 4 4 4 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 EMT52425.1 - 0.012 16.0 0.6 0.022 15.1 0.6 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EMT52425.1 - 0.016 14.6 0.0 0.92 8.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 EMT52425.1 - 0.023 14.5 0.0 3.6 7.3 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 EMT52425.1 - 0.027 14.0 0.0 0.081 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EMT52425.1 - 0.054 13.9 0.3 0.34 11.4 0.3 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EMT52425.1 - 0.072 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EMT52425.1 - 0.078 13.1 0.2 0.14 12.2 0.2 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EMT52425.1 - 0.12 12.6 0.1 0.42 10.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain QueT PF06177.11 EMT52426.1 - 6.6e-09 36.3 17.9 7.8e-09 36.0 17.9 1.1 1 0 0 1 1 1 1 QueT transporter tRNA-synt_1c PF00749.21 EMT52427.1 - 1.2e-111 372.6 0.0 1.5e-111 372.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EMT52427.1 - 5.1e-62 208.8 0.0 8.3e-62 208.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Lactamase_B PF00753.27 EMT52428.1 - 2.9e-20 73.1 0.1 6e-20 72.1 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMT52428.1 - 0.0088 15.6 0.0 0.018 14.6 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Antirestrict PF03230.13 EMT52428.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Antirestriction protein G_glu_transpept PF01019.21 EMT52429.1 - 4.8e-156 520.5 0.0 5.5e-156 520.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MCPsignal PF00015.21 EMT52430.1 - 1.4e-50 171.4 56.8 1.9e-48 164.5 27.4 3.8 1 1 2 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 EMT52430.1 - 3.8e-32 112.0 0.2 3.8e-32 112.0 0.2 3.5 3 2 0 3 3 3 1 Cache domain HAMP PF00672.25 EMT52430.1 - 9e-14 51.6 7.5 1.5e-13 50.9 0.1 4.3 5 0 0 5 5 3 1 HAMP domain DUF948 PF06103.11 EMT52430.1 - 2.6e-06 27.6 32.7 0.0027 17.9 2.6 5.7 3 2 2 5 5 5 3 Bacterial protein of unknown function (DUF948) sCache_2 PF17200.4 EMT52430.1 - 0.0057 16.5 0.0 0.0057 16.5 0.0 4.3 4 2 1 6 6 6 1 Single Cache domain 2 Serine_rich PF08824.10 EMT52430.1 - 0.18 11.8 14.2 0.18 11.8 1.1 2.9 2 2 0 2 2 2 0 Serine rich protein interaction domain Sec34 PF04136.15 EMT52430.1 - 0.27 11.1 16.3 1.3 8.8 0.6 4.3 3 1 2 5 5 5 0 Sec34-like family DUF1664 PF07889.12 EMT52430.1 - 0.53 10.3 29.2 0.022 14.8 3.1 4.6 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) ING PF12998.7 EMT52430.1 - 1.7 9.3 7.0 0.94 10.1 0.2 3.2 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding BLOC1_2 PF10046.9 EMT52430.1 - 1.7 9.0 28.2 3.5 8.0 2.4 5.3 3 2 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 dCache_2 PF08269.11 EMT52430.1 - 1.7 7.7 0.0 1.7 7.7 0.0 3.4 3 1 1 4 4 4 0 Cache domain Rad50_zn_hook PF04423.14 EMT52430.1 - 5.6 6.9 4.9 8.4 6.3 0.1 3.2 3 1 0 3 3 3 0 Rad50 zinc hook motif COG2 PF06148.11 EMT52430.1 - 6.2 6.9 25.7 4.7 7.3 1.8 5.1 2 2 3 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1759 PF03564.15 EMT52430.1 - 8.6 6.3 10.8 0.72 9.8 0.8 3.6 3 1 0 4 4 4 0 Protein of unknown function (DUF1759) Goodbye PF17109.5 EMT52430.1 - 8.8 6.8 17.9 1.1 9.7 3.2 3.7 2 2 1 3 3 3 0 fungal STAND N-terminal Goodbye domain ETC_C1_NDUFA5 PF04716.14 EMT52430.1 - 9 6.2 6.9 32 4.4 0.8 3.2 3 0 0 3 3 3 0 ETC complex I subunit conserved region Acetyltransf_6 PF13480.7 EMT52431.1 - 2.5e-06 27.7 0.4 5.4e-06 26.6 0.4 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Transcript_VP30 PF11507.8 EMT52431.1 - 0.062 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 AMP-binding PF00501.28 EMT52432.1 - 8.9e-05 21.3 0.0 0.00014 20.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme SEC-C PF02810.15 EMT52432.1 - 0.091 12.7 2.8 0.15 12.0 2.8 1.3 1 0 0 1 1 1 0 SEC-C motif Lactamase_B PF00753.27 EMT52433.1 - 3.1e-14 53.4 0.7 5.5e-14 52.6 0.7 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMT52433.1 - 1.3e-05 24.9 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain 3Beta_HSD PF01073.19 EMT52434.1 - 2.8e-41 141.4 0.0 3.6e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMT52434.1 - 9.4e-38 130.0 0.0 1.2e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMT52434.1 - 2.1e-21 76.3 0.2 1e-18 67.5 0.2 2.4 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EMT52434.1 - 4.1e-21 75.7 0.0 6.2e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMT52434.1 - 5.4e-18 65.5 0.0 7.4e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EMT52434.1 - 7.4e-18 64.6 0.0 1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EMT52434.1 - 1.8e-11 43.7 0.0 1.4e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EMT52434.1 - 3e-07 30.1 0.2 5.3e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EMT52434.1 - 1.1e-06 28.5 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EMT52434.1 - 1.9e-06 27.9 0.1 1.8e-05 24.7 0.1 2.1 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 EMT52434.1 - 3.7e-05 24.0 0.2 6.8e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 EMT52434.1 - 0.00013 21.6 0.2 0.00023 20.8 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.6 EMT52434.1 - 0.00052 19.6 0.1 0.0011 18.6 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.15 EMT52434.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 EMT52434.1 - 0.003 16.9 0.2 0.005 16.2 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DFP PF04127.15 EMT52434.1 - 0.0094 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Semialdhyde_dh PF01118.24 EMT52434.1 - 0.018 15.5 0.1 0.038 14.4 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMT52434.1 - 0.02 15.0 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EMT52434.1 - 0.022 15.2 0.1 0.047 14.1 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 EMT52434.1 - 0.03 14.9 0.1 0.058 14.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.23 EMT52434.1 - 0.048 13.8 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EMT52434.1 - 0.057 12.8 0.1 0.088 12.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_trans_4_4 PF13579.6 EMT52434.1 - 0.063 13.7 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EMT52434.1 - 0.069 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like Oxidored_nitro PF00148.19 EMT52434.1 - 0.07 11.9 0.0 4.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Mur_ligase_C PF02875.21 EMT52434.1 - 0.072 13.3 0.0 0.27 11.5 0.0 1.9 2 0 0 2 2 1 0 Mur ligase family, glutamate ligase domain F420_oxidored PF03807.17 EMT52434.1 - 0.086 13.4 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_transf_28 PF03033.20 EMT52434.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain CbiJ PF02571.14 EMT52434.1 - 0.18 11.2 0.1 0.31 10.5 0.1 1.4 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK ATP-grasp_3 PF02655.14 EMT52435.1 - 4.7e-05 23.5 0.0 0.00011 22.3 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EMT52435.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ACP_syn_III_C PF08541.10 EMT52436.1 - 5.5e-27 93.8 0.5 1.7e-25 89.0 0.4 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EMT52436.1 - 4.5e-21 74.5 0.3 1e-20 73.4 0.3 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.19 EMT52436.1 - 1.7e-09 37.5 0.2 2.6e-09 36.9 0.2 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Thiolase_N PF00108.23 EMT52436.1 - 0.00052 19.5 4.5 0.0044 16.4 1.1 2.3 2 0 0 2 2 2 2 Thiolase, N-terminal domain SpoVAD PF07451.11 EMT52436.1 - 0.019 13.7 0.6 0.032 13.0 0.6 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) GDPD PF03009.17 EMT52438.1 - 2.8e-35 122.3 0.0 7.1e-35 121.0 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Sacchrp_dh_NADP PF03435.18 EMT52438.1 - 0.0011 19.2 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDPD_2 PF13653.6 EMT52438.1 - 0.15 12.6 1.5 6.4 7.4 0.1 2.7 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family SBP_bac_8 PF13416.6 EMT52439.1 - 2.2e-48 165.5 7.7 3.3e-48 164.9 7.7 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT52439.1 - 1.4e-37 130.4 7.1 1.4e-37 130.4 7.1 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EMT52439.1 - 6.4e-06 25.7 0.6 0.092 12.1 0.2 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 EMT52440.1 - 1.8e-24 86.5 14.3 1.8e-24 86.5 14.3 2.2 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EMT52441.1 - 3e-17 63.0 17.4 3e-17 63.0 17.4 2.2 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EMT52442.1 - 3.9e-32 111.6 0.0 6.2e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 EMT52442.1 - 3.9e-09 36.6 0.1 1.1e-08 35.1 0.1 1.8 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 EMT52442.1 - 4.4e-08 33.3 0.0 0.0057 16.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT52442.1 - 3.6e-07 29.8 0.1 2.7e-06 27.0 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT52442.1 - 0.00092 19.5 0.2 0.0022 18.3 0.2 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT52442.1 - 0.0018 18.2 0.2 0.0036 17.2 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EMT52442.1 - 0.0028 17.3 0.0 0.0056 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMT52442.1 - 0.0034 17.1 0.0 0.0098 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMT52442.1 - 0.0048 17.3 0.2 0.0081 16.6 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EMT52442.1 - 0.0097 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 EMT52442.1 - 0.015 15.0 0.0 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EMT52442.1 - 0.023 15.1 0.5 0.17 12.3 0.5 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EMT52442.1 - 0.026 15.0 0.0 0.048 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EMT52442.1 - 0.03 14.1 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain OB_MalK PF17912.1 EMT52442.1 - 0.044 14.6 0.7 0.4 11.6 0.1 2.8 2 1 0 2 2 1 0 MalK OB fold domain AAA_33 PF13671.6 EMT52442.1 - 0.15 12.3 0.1 0.31 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain HAD_2 PF13419.6 EMT52443.1 - 5.2e-43 147.2 0.0 6.1e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMT52443.1 - 2.5e-20 73.7 0.8 4.8e-19 69.5 0.8 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMT52443.1 - 2e-11 44.6 1.0 3.1e-11 44.0 1.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMT52443.1 - 6.1e-09 35.8 0.0 1.4e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 EMT52443.1 - 0.00015 21.5 0.0 0.0021 17.8 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.6 EMT52443.1 - 0.00033 20.7 0.0 0.27 11.4 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMT52443.1 - 0.0048 16.7 0.0 0.65 9.7 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase G3P_antiterm PF04309.12 EMT52444.1 - 3.5e-56 189.3 0.0 3.9e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 EMT52444.1 - 8.8e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 EMT52444.1 - 0.00096 18.7 0.0 0.0026 17.2 0.0 1.7 1 1 1 2 2 2 1 Histidine biosynthesis protein IMPDH PF00478.25 EMT52444.1 - 0.0096 15.0 0.0 0.023 13.7 0.0 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain PcrB PF01884.17 EMT52444.1 - 0.031 13.7 0.0 0.52 9.7 0.0 2.3 2 1 0 2 2 2 0 PcrB family PNP_UDP_1 PF01048.20 EMT52445.1 - 1.5e-42 145.4 1.1 1.7e-42 145.3 1.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Oxidored_molyb PF00174.19 EMT52446.1 - 3.9e-39 134.0 0.0 5.3e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain BPD_transp_2 PF02653.16 EMT52447.1 - 2.8e-35 121.8 39.7 3.2e-35 121.6 39.7 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 EMT52448.1 - 3.3e-38 131.4 31.8 3.3e-38 131.4 31.8 2.0 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component DUF2953 PF11167.8 EMT52448.1 - 0.1 12.7 0.7 0.96 9.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) DUF2976 PF11190.8 EMT52448.1 - 6.2 6.7 9.6 0.32 10.8 0.2 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF2976) ABC_tran PF00005.27 EMT52449.1 - 7e-54 182.1 0.0 4.2e-33 114.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMT52449.1 - 5.9e-08 32.9 0.0 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT52449.1 - 3e-06 26.9 0.5 0.01 15.6 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMT52449.1 - 3.6e-06 27.0 0.1 0.018 14.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 EMT52449.1 - 1.3e-05 24.9 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EMT52449.1 - 0.00012 21.6 0.2 0.4 10.1 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT52449.1 - 0.00017 21.4 0.1 0.039 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EMT52449.1 - 0.00051 20.6 0.1 0.0018 18.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EMT52449.1 - 0.0021 18.0 0.7 0.22 11.4 0.2 2.7 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 EMT52449.1 - 0.0036 17.6 1.3 0.026 14.8 0.3 2.6 2 1 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 EMT52449.1 - 0.0038 17.3 0.6 0.66 10.1 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase ABC_ATPase PF09818.9 EMT52449.1 - 0.011 14.5 4.4 4 6.1 0.0 3.9 4 1 0 4 4 4 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 EMT52449.1 - 0.012 15.4 0.2 1 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMT52449.1 - 0.013 15.3 3.2 0.046 13.4 0.5 2.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMT52449.1 - 0.021 15.2 0.2 0.82 10.0 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain DUF3584 PF12128.8 EMT52449.1 - 0.026 12.0 0.0 0.038 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATP-synt_ab PF00006.25 EMT52449.1 - 0.049 13.3 0.1 1.5 8.4 0.0 2.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DLIC PF05783.11 EMT52449.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_13 PF13166.6 EMT52449.1 - 0.068 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EMT52449.1 - 0.081 12.5 0.4 0.51 9.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CobA_CobO_BtuR PF02572.15 EMT52449.1 - 0.1 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP NACHT PF05729.12 EMT52449.1 - 0.1 12.5 0.2 0.42 10.5 0.0 2.1 3 0 0 3 3 3 0 NACHT domain Bmp PF02608.14 EMT52450.1 - 4.6e-59 199.9 3.2 5.2e-59 199.7 3.2 1.0 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Peripla_BP_1 PF00532.21 EMT52450.1 - 4e-13 49.4 0.3 5.1e-13 49.1 0.3 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 EMT52450.1 - 1.9e-11 44.0 5.6 2.8e-11 43.5 5.6 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain ABC_sub_bind PF04392.12 EMT52450.1 - 0.0069 15.7 0.4 0.22 10.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter substrate binding protein tRNA-synt_His PF13393.6 EMT52450.1 - 0.052 12.8 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase LPAM_1 PF08139.12 EMT52450.1 - 2.1 9.0 3.6 6.4 7.5 3.6 1.9 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site PepSY_2 PF13670.6 EMT52450.1 - 6.5 6.8 7.0 4.2 7.4 0.0 2.7 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain MCPsignal PF00015.21 EMT52451.1 - 1.6e-35 122.4 47.7 1.1e-33 116.5 21.2 4.0 1 1 2 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 EMT52451.1 - 0.013 15.8 34.3 0.28 11.5 2.0 5.2 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 EMT52451.1 - 0.057 13.7 34.0 0.64 10.3 6.8 5.2 2 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.11 EMT52451.1 - 0.94 10.1 28.2 0.07 13.7 1.1 4.1 2 2 2 4 4 4 0 Syntaxin 6, N-terminal Laminin_II PF06009.12 EMT52451.1 - 3.2 7.8 36.9 0.17 11.9 11.7 3.8 2 2 2 4 4 4 0 Laminin Domain II DUF1664 PF07889.12 EMT52451.1 - 3.8 7.6 31.3 5 7.2 1.7 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) RPW8 PF05659.11 EMT52451.1 - 4.2 7.0 14.4 1.7 8.3 1.8 3.7 2 2 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Helo_like_N PF17111.5 EMT52451.1 - 4.5 6.6 20.6 0.34 10.2 0.7 4.1 2 1 4 6 6 6 0 Fungal N-terminal domain of STAND proteins GIDA PF01134.22 EMT52452.1 - 7.6e-10 38.4 0.4 0.00033 19.9 0.2 3.2 2 1 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EMT52452.1 - 1.7e-08 34.1 1.7 7.9e-05 22.0 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMT52452.1 - 5.8e-08 32.2 0.8 0.00037 19.7 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 EMT52452.1 - 1.7e-06 27.5 0.2 8.9e-05 21.8 0.0 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EMT52452.1 - 1.9e-06 26.8 0.0 4.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EMT52452.1 - 2.7e-06 27.2 0.2 4.5e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMT52452.1 - 6.9e-06 26.2 0.0 8.5e-05 22.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMT52452.1 - 0.00011 21.5 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EMT52452.1 - 0.0016 17.7 1.0 0.017 14.4 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMT52452.1 - 0.0034 16.8 0.4 0.072 12.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMT52452.1 - 0.0054 16.0 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain zf-CCHC_6 PF15288.6 EMT52452.1 - 0.041 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Zinc knuckle NAD_binding_9 PF13454.6 EMT52452.1 - 0.079 12.9 0.0 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Na_Ala_symp PF01235.17 EMT52454.1 - 1.1e-164 548.4 37.3 1.8e-164 547.7 37.3 1.2 1 0 0 1 1 1 1 Sodium:alanine symporter family Ala_racemase_N PF01168.20 EMT52455.1 - 6.7e-11 42.3 0.0 8.6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain ALO PF04030.14 EMT52456.1 - 1.7e-74 250.9 1.1 2.1e-74 250.6 1.1 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EMT52456.1 - 1.3e-29 102.7 3.7 1.8e-29 102.2 3.7 1.2 1 0 0 1 1 1 1 FAD binding domain OsmC PF02566.19 EMT52457.1 - 1.3e-20 73.7 0.1 1.6e-20 73.4 0.1 1.1 1 0 0 1 1 1 1 OsmC-like protein Xan_ur_permease PF00860.20 EMT52458.1 - 2.4e-76 256.9 47.3 2.9e-76 256.7 47.3 1.1 1 0 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EMT52458.1 - 0.00071 20.0 8.5 0.00071 20.0 8.5 3.7 1 1 1 3 3 3 1 Molybdate transporter of MFS superfamily Rieske PF00355.26 EMT52459.1 - 6.2e-21 74.1 0.0 1.4e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain LPAM_1 PF08139.12 EMT52460.1 - 3.4 8.3 4.4 12 6.6 4.4 1.9 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Peptidase_M29 PF02073.15 EMT52461.1 - 3.3e-13 49.2 0.0 1.7e-11 43.5 0.0 2.1 1 1 1 2 2 2 2 Thermophilic metalloprotease (M29) TIR_2 PF13676.6 EMT52461.1 - 0.013 16.1 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 TIR domain Molybdopterin_N PF18364.1 EMT52461.1 - 0.14 12.2 0.0 0.45 10.6 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain AroM PF07302.11 EMT52462.1 - 3.8e-73 245.5 0.1 4.3e-73 245.3 0.1 1.0 1 0 0 1 1 1 1 AroM protein DUF1177 PF06675.11 EMT52463.1 - 3.4e-139 462.3 2.2 3.9e-139 462.1 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1177) PSP PF04046.16 EMT52463.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 PSP DUF917 PF06032.12 EMT52464.1 - 8.4e-61 205.7 4.1 1e-60 205.5 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF917) OPT PF03169.15 EMT52465.1 - 1e-30 107.0 50.5 4.8e-18 65.2 33.5 2.1 1 1 1 2 2 2 2 OPT oligopeptide transporter protein IclR PF01614.18 EMT52466.1 - 1.7e-27 95.8 0.0 2.3e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EMT52466.1 - 3.8e-11 42.6 0.0 7.2e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 EMT52466.1 - 1.6e-05 24.7 0.1 7.5e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 EMT52466.1 - 0.00031 20.6 0.0 0.034 14.0 0.0 2.4 2 0 0 2 2 2 1 MarR family FeoC PF09012.10 EMT52466.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_11 PF08279.12 EMT52466.1 - 0.0016 18.4 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 EMT52466.1 - 0.0041 17.0 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.6 EMT52466.1 - 0.0042 16.8 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Rrf2 PF02082.20 EMT52466.1 - 0.0042 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator FUR PF01475.19 EMT52466.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family Fe_dep_repress PF01325.19 EMT52466.1 - 0.016 15.4 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain PadR PF03551.14 EMT52466.1 - 0.026 14.5 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_32 PF13565.6 EMT52466.1 - 0.028 15.0 0.2 0.1 13.3 0.0 2.0 2 0 0 2 2 1 0 Homeodomain-like domain HTH_28 PF13518.6 EMT52466.1 - 0.042 14.0 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 EMT52466.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2250 PF10007.9 EMT52466.1 - 0.052 13.7 0.1 0.34 11.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_29 PF13551.6 EMT52466.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix UPF0240 PF06784.11 EMT52466.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) HTH_7 PF02796.15 EMT52466.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 EMT52466.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Mga PF05043.13 EMT52466.1 - 0.12 12.9 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain PucR PF07905.11 EMT52467.1 - 3.8e-30 104.5 0.0 7.9e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 EMT52467.1 - 1.5e-19 69.5 0.1 3.1e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 EMT52467.1 - 2.7e-12 47.0 0.0 7.7e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 GGDEF-like domain HAD PF12710.7 EMT52468.1 - 3.1e-09 37.5 0.0 4.7e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EMT52468.1 - 0.029 13.9 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Ldh_1_N PF00056.23 EMT52470.1 - 9.2e-42 142.5 0.2 1.3e-41 142.0 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EMT52470.1 - 1.8e-27 96.3 0.0 3.9e-27 95.2 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 EMT52470.1 - 3.7e-05 23.4 1.1 0.00013 21.6 1.1 1.8 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.16 EMT52470.1 - 0.00029 20.4 0.3 0.14 11.7 0.0 2.4 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase DAO PF01266.24 EMT52470.1 - 0.00079 19.1 0.5 0.0026 17.4 0.3 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EMT52470.1 - 0.021 14.7 0.9 0.14 12.1 0.3 2.4 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EMT52470.1 - 0.022 14.0 0.1 0.034 13.4 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMT52470.1 - 0.041 14.1 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF1188 PF06690.11 EMT52470.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) EutC PF05985.11 EMT52471.1 - 2.6e-80 269.1 0.0 4.2e-80 268.4 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine ammonia-lyase light chain (EutC) EutB PF06751.11 EMT52472.1 - 5.8e-214 710.8 0.1 6.6e-214 710.6 0.1 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia lyase large subunit (EutB) DUF1192 PF06698.11 EMT52472.1 - 0.077 13.1 0.3 0.18 11.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) EutA PF06277.11 EMT52473.1 - 3.5e-152 507.6 0.2 4.1e-152 507.4 0.2 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutA FtsA PF14450.6 EMT52473.1 - 0.00041 20.7 0.4 0.15 12.5 0.0 2.7 2 2 0 2 2 2 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 EMT52473.1 - 0.026 14.0 0.7 0.56 9.6 0.3 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Response_reg PF00072.24 EMT52474.1 - 9.7e-31 106.2 0.5 2e-30 105.2 0.5 1.5 1 0 0 1 1 1 1 Response regulator receiver domain ANTAR PF03861.14 EMT52474.1 - 8.2e-18 64.0 0.8 2.7e-17 62.3 0.8 1.9 1 0 0 1 1 1 1 ANTAR domain HydF_dimer PF18128.1 EMT52474.1 - 0.028 14.5 0.7 0.056 13.5 0.0 1.9 2 1 0 2 2 2 0 Hydrogen maturase F dimerization domain H_kinase_N PF12282.8 EMT52475.1 - 1.9e-31 108.9 0.4 3.5e-31 108.1 0.4 1.5 1 0 0 1 1 1 1 Signal transduction histidine kinase HisKA_2 PF07568.12 EMT52475.1 - 1.9e-25 88.7 6.2 8.4e-25 86.7 6.2 2.2 1 0 0 1 1 1 1 Histidine kinase HWE_HK PF07536.14 EMT52475.1 - 5.4e-09 36.6 0.9 1.2e-08 35.6 0.9 1.6 1 0 0 1 1 1 1 HWE histidine kinase HATPase_c PF02518.26 EMT52475.1 - 7.5e-08 32.9 0.3 4.1e-07 30.5 0.3 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT52475.1 - 1.6e-07 31.3 0.0 4.2e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_4 PF08448.10 EMT52475.1 - 0.00014 22.1 0.0 0.018 15.2 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 EMT52475.1 - 0.0023 17.9 0.0 0.0066 16.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EMT52475.1 - 0.036 14.1 0.2 0.74 9.8 0.0 3.2 3 1 0 3 3 3 0 PAS fold Capsule_synth PF05159.14 EMT52475.1 - 0.073 12.5 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein PAS_7 PF12860.7 EMT52475.1 - 0.077 13.2 0.2 4.5 7.5 0.0 3.3 4 0 0 4 4 4 0 PAS fold PIN_6 PF17146.4 EMT52475.1 - 0.16 12.5 0.2 0.16 12.5 0.2 2.4 3 0 0 3 3 3 0 PIN domain of ribonuclease SAPIS-gp6 PF16722.5 EMT52475.1 - 0.32 11.4 3.9 1.9 9.0 1.3 2.5 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus Synthase_beta PF11421.8 EMT52475.1 - 0.45 11.3 2.7 1.1 10.1 0.1 2.5 2 0 0 2 2 2 0 ATP synthase F1 beta subunit PduV-EutP PF10662.9 EMT52476.1 - 2e-41 141.1 0.0 2.2e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EMT52476.1 - 4.7e-06 26.7 0.0 7.3e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMT52476.1 - 9.5e-05 22.0 0.0 0.23 11.0 0.0 2.8 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain TniB PF05621.11 EMT52476.1 - 0.00039 19.9 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein Dynamin_N PF00350.23 EMT52476.1 - 0.002 18.2 0.0 0.11 12.5 0.0 2.2 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EMT52476.1 - 0.0063 16.4 0.0 3.4 7.5 0.0 2.9 2 1 1 3 3 3 1 RsgA GTPase Roc PF08477.13 EMT52476.1 - 0.0069 16.6 0.0 0.017 15.4 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EMT52476.1 - 0.014 14.9 0.0 0.66 9.5 0.0 2.4 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 EMT52476.1 - 0.033 14.7 0.0 0.04 14.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EMT52476.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 EMT52476.1 - 0.085 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arf PF00025.21 EMT52476.1 - 0.13 11.7 0.0 10 5.5 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family SRPRB PF09439.10 EMT52476.1 - 0.13 11.6 0.0 0.34 10.3 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit BMC PF00936.19 EMT52477.1 - 1.2e-15 57.3 1.4 1.2e-15 57.3 1.4 1.5 2 0 0 2 2 2 1 BMC domain EutN_CcmL PF03319.13 EMT52478.1 - 2.3e-31 108.2 0.3 2.7e-31 108.0 0.3 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutN/carboxysome PTAC PF06130.12 EMT52480.1 - 7.6e-49 163.8 0.0 7.4e-31 106.2 0.0 2.5 3 0 0 3 3 3 2 Phosphate propanoyltransferase Molydop_binding PF01568.21 EMT52480.1 - 0.0039 17.2 0.8 0.92 9.6 0.0 3.1 4 0 0 4 4 4 2 Molydopterin dinucleotide binding domain BMC PF00936.19 EMT52481.1 - 1.3e-26 92.3 8.9 1.6e-26 92.1 8.9 1.1 1 0 0 1 1 1 1 BMC domain Aldedh PF00171.22 EMT52482.1 - 3.6e-28 98.3 7.2 6.1e-28 97.5 7.2 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3783 PF12646.7 EMT52482.1 - 0.055 13.4 0.2 0.23 11.5 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) LacI PF00356.21 EMT52482.1 - 0.094 12.5 0.0 0.91 9.4 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family LepB_N PF18640.1 EMT52482.1 - 0.23 11.0 0.5 9.6 5.8 0.1 2.4 2 0 0 2 2 2 0 LepB N-terminal domain BMC PF00936.19 EMT52483.1 - 1.2e-25 89.3 5.0 1.2e-25 89.3 5.0 1.5 2 0 0 2 2 2 1 BMC domain SIN1 PF05422.12 EMT52483.1 - 0.045 14.3 0.6 0.064 13.8 0.6 1.3 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Rho_N PF07498.12 EMT52483.1 - 0.072 13.0 0.5 0.37 10.8 0.5 2.0 1 1 0 1 1 1 0 Rho termination factor, N-terminal domain BMC PF00936.19 EMT52484.1 - 4.1e-17 61.9 6.3 9.6e-12 44.7 0.7 2.4 2 1 0 2 2 2 2 BMC domain LysR_substrate PF03466.20 EMT52485.1 - 4e-50 170.1 0.0 5.8e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT52485.1 - 2.8e-22 78.4 1.3 6e-22 77.4 0.7 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 EMT52485.1 - 0.00034 19.8 0.0 0.0005 19.2 0.0 1.4 1 0 0 1 1 1 1 PBP superfamily domain HTH_5 PF01022.20 EMT52485.1 - 0.0034 17.2 0.0 0.013 15.4 0.0 2.0 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 EMT52485.1 - 0.0091 15.9 0.3 0.13 12.1 0.1 2.7 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 EMT52485.1 - 0.014 15.0 0.1 0.11 12.1 0.0 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EMT52485.1 - 0.022 14.8 0.1 0.15 12.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 EMT52485.1 - 0.023 14.5 0.0 0.31 10.9 0.0 2.9 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain SSFA2_C PF14723.6 EMT52485.1 - 0.28 11.1 1.5 1.7 8.6 0.7 2.2 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Cons_hypoth698 PF03601.14 EMT52486.1 - 4.2e-76 255.7 15.8 5e-76 255.5 15.8 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 698 Methyltransf_16 PF10294.9 EMT52486.1 - 0.036 13.8 0.1 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PepSY PF03413.19 EMT52487.1 - 5.6e-15 55.6 2.3 7.1e-15 55.3 2.3 1.1 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY_2 PF13670.6 EMT52487.1 - 3.2e-07 30.3 0.2 5.3e-07 29.6 0.2 1.3 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain GFO_IDH_MocA PF01408.22 EMT52488.1 - 3.8e-32 111.6 0.4 6.3e-32 110.9 0.4 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMT52488.1 - 2.5e-12 46.8 0.1 7.5e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EMT52488.1 - 2.1e-06 28.4 0.1 3.5e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMT52488.1 - 2.2e-05 24.6 0.1 5e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 EMT52488.1 - 0.00025 21.5 0.0 0.00051 20.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EMT52488.1 - 0.00039 19.8 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EMT52488.1 - 0.00056 20.4 0.1 0.0011 19.5 0.1 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EMT52488.1 - 0.0025 18.1 0.6 0.01 16.1 0.1 2.2 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EMT52488.1 - 0.095 12.9 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase OCD_Mu_crystall PF02423.15 EMT52488.1 - 0.14 11.1 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family ABC_tran PF00005.27 EMT52489.1 - 1.4e-25 90.4 0.0 2.6e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT52489.1 - 1.4e-10 41.5 4.1 4.8e-07 29.9 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT52489.1 - 0.0059 16.3 0.8 0.011 15.5 0.5 1.6 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EMT52489.1 - 0.011 15.5 0.0 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 EMT52489.1 - 0.011 16.2 0.0 0.015 15.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 EMT52489.1 - 0.016 15.3 0.0 0.027 14.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 EMT52489.1 - 0.019 15.5 0.2 0.046 14.2 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMT52489.1 - 0.047 13.9 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EMT52489.1 - 0.059 13.3 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EMT52489.1 - 0.079 13.5 0.0 0.2 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EMT52489.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 EMT52489.1 - 0.096 13.0 0.1 0.33 11.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMT52489.1 - 0.1 12.3 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EMT52489.1 - 0.14 11.1 0.8 0.23 10.4 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 EMT52489.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EMT52489.1 - 0.17 11.8 0.1 9.2 6.1 0.0 2.3 2 0 0 2 2 2 0 NTPase EcsB PF05975.12 EMT52490.1 - 1.1e-61 208.8 26.0 1.4e-61 208.5 26.0 1.1 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB SPC12 PF06645.13 EMT52490.1 - 1.5 8.9 17.2 1.3 9.2 0.5 4.2 4 0 0 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3169 PF11368.8 EMT52490.1 - 2.2 7.7 6.6 16 4.9 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) LysR_substrate PF03466.20 EMT52491.1 - 2.2e-53 180.8 0.3 3.1e-53 180.3 0.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT52491.1 - 2.8e-20 72.0 0.1 5.8e-20 71.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 EMT52491.1 - 0.083 12.8 0.2 5.1 7.1 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family ELFV_dehydrog PF00208.21 EMT52492.1 - 1.9e-79 266.9 0.1 1.1e-78 264.3 0.2 1.9 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EMT52492.1 - 1.7e-56 189.7 0.0 3.8e-56 188.5 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 EMT52492.1 - 9.9e-07 28.3 0.0 1.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.19 EMT52492.1 - 0.033 12.9 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Bac_GDH PF05088.12 EMT52492.1 - 0.083 10.4 0.0 0.12 9.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DEAD PF00270.29 EMT52493.1 - 2.6e-51 173.9 1.5 4.3e-51 173.2 0.6 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMT52493.1 - 2.3e-32 111.6 0.3 3.1e-30 104.8 0.0 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMT52493.1 - 1.3e-07 31.7 0.2 4.7e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EMT52493.1 - 0.0003 20.7 0.1 0.00056 19.8 0.1 1.5 1 0 0 1 1 1 1 Helicase SWI2_SNF2 PF18766.1 EMT52493.1 - 0.021 14.5 0.2 0.044 13.5 0.2 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase UvrA_inter PF17760.1 EMT52493.1 - 0.034 14.2 0.0 0.14 12.2 0.0 2.1 1 1 0 1 1 1 0 UvrA interaction domain Flavi_DEAD PF07652.14 EMT52493.1 - 0.045 13.7 0.7 0.19 11.7 0.7 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain ERCC3_RAD25_C PF16203.5 EMT52493.1 - 0.054 12.7 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CSD PF00313.22 EMT52494.1 - 6.5e-33 112.4 1.7 6.9e-33 112.3 1.7 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EMT52494.1 - 0.0041 16.8 1.6 0.0043 16.7 1.1 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain SBP_bac_3 PF00497.20 EMT52495.1 - 8.7e-45 152.9 0.3 8.7e-45 152.9 0.3 1.8 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EMT52495.1 - 4.2e-05 23.7 0.0 0.0016 18.7 0.0 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ETRAMP PF09716.10 EMT52495.1 - 0.67 10.1 4.3 0.33 11.0 1.0 2.1 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) MCPsignal PF00015.21 EMT52496.1 - 2.9e-48 163.9 46.5 1.3e-44 152.0 25.5 3.8 1 1 2 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 EMT52496.1 - 4.1e-28 98.8 3.1 4.1e-28 98.8 3.1 3.5 3 2 2 5 5 5 1 Cache domain HAMP PF00672.25 EMT52496.1 - 9.3e-11 41.9 7.3 1.4e-10 41.4 0.0 4.4 6 1 0 6 6 5 1 HAMP domain dCache_2 PF08269.11 EMT52496.1 - 1.4e-06 27.7 0.1 1.4e-06 27.7 0.1 3.1 2 1 0 2 2 2 1 Cache domain DUF1664 PF07889.12 EMT52496.1 - 2.5e-05 24.3 25.2 0.043 13.8 0.9 4.7 3 1 2 5 5 5 4 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EMT52496.1 - 3.2e-05 24.1 15.9 0.0076 16.5 1.3 4.8 3 2 1 4 4 4 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EMT52496.1 - 0.00095 19.4 37.3 0.0078 16.4 6.6 6.0 3 2 1 5 5 5 3 Bacterial protein of unknown function (DUF948) DUF5420 PF17457.2 EMT52496.1 - 0.012 15.6 0.3 0.056 13.3 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5420) Laminin_II PF06009.12 EMT52496.1 - 0.41 10.7 34.9 0.2 11.7 3.7 4.9 3 2 2 5 5 5 0 Laminin Domain II Sec34 PF04136.15 EMT52496.1 - 1.2 9.0 11.8 4.4 7.2 0.2 4.1 3 1 1 4 4 4 0 Sec34-like family Snapin_Pallidin PF14712.6 EMT52496.1 - 1.3 9.5 8.5 8.2 6.9 0.5 4.9 4 3 1 5 5 5 0 Snapin/Pallidin TF_AP-2 PF03299.14 EMT52496.1 - 2.6 8.0 17.9 0.32 10.9 0.2 4.5 2 1 3 5 5 5 0 Transcription factor AP-2 COG2 PF06148.11 EMT52496.1 - 2.8 8.0 20.4 4 7.5 4.9 4.3 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 SARAF PF06682.12 EMT52497.1 - 0.00067 19.4 0.1 0.0063 16.2 0.0 1.9 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis ECF_trnsprt PF12822.7 EMT52497.1 - 0.011 15.9 1.1 0.011 15.9 1.1 1.6 2 0 0 2 2 2 0 ECF transporter, substrate-specific component DUF2207 PF09972.9 EMT52497.1 - 0.013 14.3 0.2 0.015 14.1 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5326 PF17260.2 EMT52497.1 - 3 8.1 7.8 0.16 12.1 2.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5326) DUF2407_C PF13373.6 EMT52497.1 - 3.4 7.9 4.5 6.6 6.9 0.1 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain Romo1 PF10247.9 EMT52497.1 - 4.3 7.8 8.3 0.18 12.2 1.4 2.0 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Glycophorin_A PF01102.18 EMT52497.1 - 5.8 7.2 9.6 33 4.8 9.6 2.1 1 1 0 1 1 1 0 Glycophorin A Podoplanin PF05808.11 EMT52497.1 - 9.8 6.3 10.4 32 4.6 10.4 1.8 1 1 0 1 1 1 0 Podoplanin DUF2653 PF10850.8 EMT52498.1 - 1e-37 128.2 1.6 1.2e-37 128.0 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2653) RasGEF_N PF00618.20 EMT52498.1 - 0.086 13.1 0.0 0.092 13.0 0.0 1.2 1 0 0 1 1 1 0 RasGEF N-terminal motif Response_reg PF00072.24 EMT52499.1 - 4e-31 107.5 2.1 6.2e-31 106.9 2.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT52499.1 - 8.6e-26 89.8 0.2 1.5e-25 89.1 0.2 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal GerE PF00196.19 EMT52499.1 - 0.0039 16.7 0.5 0.34 10.5 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, luxR family THUMP PF02926.17 EMT52499.1 - 0.018 15.2 1.4 0.02 15.0 0.3 1.6 2 0 0 2 2 2 0 THUMP domain HisKA PF00512.25 EMT52500.1 - 1.4e-15 57.0 0.2 1.7e-14 53.6 0.0 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 EMT52500.1 - 1.3e-10 41.8 0.0 3e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EMT52500.1 - 8.2e-07 28.9 0.0 2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 GHKL domain DUF3429 PF11911.8 EMT52500.1 - 0.21 11.9 2.2 0.3 11.4 0.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3429) Wzy_C PF04932.15 EMT52500.1 - 2.1 8.0 6.5 27 4.4 0.1 2.7 3 0 0 3 3 3 0 O-Antigen ligase OpuAC PF04069.12 EMT52501.1 - 1.1e-68 231.6 8.0 1.8e-45 155.5 0.4 2.0 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system BPD_transp_1 PF00528.22 EMT52502.1 - 1.4e-25 90.1 11.1 1.4e-25 90.1 11.1 2.2 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_membrane_3 PF13748.6 EMT52502.1 - 0.025 13.8 0.4 0.067 12.4 0.4 1.6 1 0 0 1 1 1 0 ABC transporter transmembrane region ABC_tran PF00005.27 EMT52503.1 - 2.6e-35 121.9 0.0 6.7e-35 120.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter CBS PF00571.28 EMT52503.1 - 8.5e-12 45.3 1.0 0.00018 21.9 0.2 2.9 3 0 0 3 3 2 2 CBS domain AAA_16 PF13191.6 EMT52503.1 - 4.8e-05 23.8 0.0 9.9e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EMT52503.1 - 0.00018 21.5 0.3 0.26 11.1 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMT52503.1 - 0.00052 20.3 0.3 0.0032 17.7 0.2 2.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMT52503.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMT52503.1 - 0.0059 16.5 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase DUF3987 PF13148.6 EMT52503.1 - 0.0068 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) ABC_ATPase PF09818.9 EMT52503.1 - 0.0075 15.1 0.1 0.43 9.3 0.1 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.6 EMT52503.1 - 0.012 16.1 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMT52503.1 - 0.013 15.2 0.1 0.075 12.7 0.0 2.4 2 2 1 3 3 3 0 AAA domain AAA_33 PF13671.6 EMT52503.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMT52503.1 - 0.057 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 EMT52503.1 - 0.07 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain SMC_N PF02463.19 EMT52503.1 - 0.074 12.5 1.5 1.8 7.9 1.5 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 EMT52503.1 - 0.075 12.4 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Adeno_IVa2 PF02456.15 EMT52503.1 - 0.084 11.6 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein G-alpha PF00503.20 EMT52503.1 - 0.087 12.0 0.0 0.31 10.2 0.0 1.6 1 1 1 2 2 2 0 G-protein alpha subunit ATPase_2 PF01637.18 EMT52503.1 - 0.14 12.0 0.3 0.5 10.2 0.3 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea MarR PF01047.22 EMT52504.1 - 0.0089 15.9 0.1 0.085 12.8 0.1 2.3 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 EMT52504.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain TrmB PF01978.19 EMT52504.1 - 0.058 13.3 0.1 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF1304 PF06993.12 EMT52504.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) HTH_9 PF08221.11 EMT52504.1 - 0.15 12.2 0.2 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HATPase_c PF02518.26 EMT52505.1 - 1.9e-17 63.8 0.0 3.1e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EMT52505.1 - 1.1e-05 25.3 0.1 0.00013 21.8 0.0 2.5 3 0 0 3 3 3 1 GHKL domain 7tm_3 PF00003.22 EMT52505.1 - 0.0023 17.7 1.5 0.0023 17.7 1.5 2.4 2 1 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR HisKA PF00512.25 EMT52505.1 - 0.024 14.7 0.2 0.061 13.4 0.2 1.7 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Lectin_N PF03954.14 EMT52505.1 - 0.043 13.6 0.1 0.098 12.4 0.1 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain HATPase_c_3 PF13589.6 EMT52505.1 - 0.19 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2663 PF10864.8 EMT52505.1 - 0.21 12.0 2.3 1.4 9.4 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) dCache_2 PF08269.11 EMT52505.1 - 0.37 9.9 2.0 0.61 9.2 2.0 1.2 1 0 0 1 1 1 0 Cache domain DUF4293 PF14126.6 EMT52505.1 - 1.2 9.4 9.1 1.1 9.5 6.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF2157 PF09925.9 EMT52505.1 - 1.8 8.3 10.3 1.9 8.3 1.6 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Response_reg PF00072.24 EMT52506.1 - 1.2e-16 60.8 0.8 2e-16 60.1 0.2 1.7 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 EMT52506.1 - 8e-13 47.7 1.1 1.4e-12 47.0 1.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EMT52506.1 - 1.1e-05 25.0 0.1 2.2e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT52506.1 - 9.2e-05 21.9 0.2 0.00021 20.7 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_20 PF12840.7 EMT52506.1 - 0.00036 20.5 0.0 0.00068 19.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2089 PF09862.9 EMT52506.1 - 0.00071 19.6 0.9 0.0017 18.3 0.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2089) HTH_11 PF08279.12 EMT52506.1 - 0.0018 18.2 2.0 0.0021 18.0 0.8 1.7 2 0 0 2 2 2 1 HTH domain HTH_23 PF13384.6 EMT52506.1 - 0.0034 17.1 0.3 0.0085 15.9 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 EMT52506.1 - 0.0052 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_40 PF14493.6 EMT52506.1 - 0.01 16.3 3.2 0.022 15.2 1.7 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain ABC2_membrane_3 PF12698.7 EMT52506.1 - 0.043 12.9 0.1 0.048 12.8 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3874 PF12990.7 EMT52506.1 - 0.19 12.1 0.6 6.2 7.2 0.3 2.7 2 1 0 2 2 2 0 Domain of unknonw function from B. Theta Gene description (DUF3874) Ribosomal_60s PF00428.19 EMT52506.1 - 0.84 10.3 4.8 4.3 8.0 0.5 2.7 2 1 0 2 2 2 0 60s Acidic ribosomal protein AMP-binding PF00501.28 EMT52507.1 - 1.1e-64 218.6 0.0 1.5e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Acyltransferase PF01553.21 EMT52507.1 - 1.1e-17 63.9 0.1 4.7e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase AMP-binding_C PF13193.6 EMT52507.1 - 0.0074 17.2 0.0 0.015 16.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EMT52508.1 - 4.8e-23 81.6 40.6 4.8e-23 81.6 40.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 EMT52508.1 - 1.1e-06 27.3 24.8 1.4e-06 27.0 24.8 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MMR_HSR1 PF01926.23 EMT52510.1 - 0.0036 17.4 0.0 0.0073 16.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF463 PF04317.12 EMT52510.1 - 0.0076 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 YcjX-like family, DUF463 AAA_14 PF13173.6 EMT52510.1 - 0.0083 16.2 0.7 0.04 14.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EMT52510.1 - 0.032 14.6 0.0 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 EMT52510.1 - 0.086 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family FYDLN_acid PF09538.10 EMT52510.1 - 0.1 13.3 0.1 1.4 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PPV_E1_C PF00519.17 EMT52510.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase AAA_29 PF13555.6 EMT52510.1 - 0.14 11.9 0.2 0.26 11.0 0.2 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain zinc_ribbon_16 PF17034.5 EMT52510.1 - 0.18 12.0 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family VWA PF00092.28 EMT52512.1 - 3.4e-21 76.3 0.1 4.6e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EMT52512.1 - 7.6e-15 55.5 0.1 1.5e-14 54.5 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EMT52512.1 - 5.7e-13 49.1 0.0 7.7e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EMT52512.1 - 8.8e-09 35.1 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 EMT52512.1 - 0.0018 18.4 0.1 0.0032 17.6 0.1 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Gly-zipper_YMGG PF13441.6 EMT52512.1 - 0.012 15.4 5.2 0.014 15.2 1.2 2.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 EMT52512.1 - 0.94 9.5 6.5 9.2 6.4 2.0 2.8 2 0 0 2 2 2 0 Glycine zipper Tubulin_2 PF13809.6 EMT52513.1 - 0.00014 21.1 0.1 0.00024 20.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin like SlyX PF04102.12 EMT52513.1 - 0.0072 16.9 3.1 0.0072 16.9 3.1 2.7 2 0 0 2 2 2 1 SlyX Sec2p PF06428.11 EMT52513.1 - 2.4 8.2 8.5 0.33 10.9 3.4 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Tubulin_2 PF13809.6 EMT52514.1 - 5.6e-82 275.7 0.1 8.9e-82 275.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin PF00091.25 EMT52514.1 - 0.002 18.4 0.3 0.042 14.0 0.2 2.9 3 0 0 3 3 3 1 Tubulin/FtsZ family, GTPase domain HEPN_RES_NTD1 PF18870.1 EMT52514.1 - 0.16 12.2 5.7 9.2 6.5 0.0 3.5 3 1 0 3 3 3 0 HEPN/RES N-terminal domain 1 VWA PF00092.28 EMT52515.1 - 1.1e-17 64.8 2.9 1.9e-17 64.1 2.9 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EMT52515.1 - 5.6e-13 49.5 0.6 1.6e-12 48.0 0.6 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EMT52515.1 - 2.7e-06 27.4 0.1 6.4e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain MG2 PF01835.19 EMT52515.1 - 0.00039 20.8 0.1 0.014 15.9 0.0 2.8 3 0 0 3 3 3 1 MG2 domain Gemini_mov PF01708.16 EMT52515.1 - 0.014 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF1206 PF06724.11 EMT52515.1 - 0.019 15.0 0.1 0.054 13.6 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF1652 PF07865.11 EMT52515.1 - 0.071 12.9 0.0 10 6.0 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1652) DUF2914 PF11141.8 EMT52515.1 - 0.1 12.4 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) BT1 PF03092.16 EMT52516.1 - 0.12 10.6 0.0 0.14 10.4 0.0 1.0 1 0 0 1 1 1 0 BT1 family RecR PF02132.15 EMT52517.1 - 0.032 13.8 1.9 0.09 12.4 1.9 1.8 1 0 0 1 1 1 0 RecR protein TBK1_CCD1 PF18394.1 EMT52517.1 - 0.27 10.8 3.7 13 5.3 0.7 2.7 3 0 0 3 3 3 0 TANK-binding kinase 1 coiled-coil domain 1 SH3_3 PF08239.11 EMT52518.1 - 1.7e-09 37.8 0.2 4.5e-09 36.5 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 EMT52518.1 - 0.0005 19.8 0.1 0.0011 18.7 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain TPR_7 PF13176.6 EMT52518.1 - 0.061 13.4 3.6 0.94 9.7 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMT52518.1 - 0.12 12.5 6.5 1.6 9.1 0.7 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMT52518.1 - 2.7 8.0 4.4 3.3 7.7 2.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RQC PF09382.10 EMT52519.1 - 4.5e-33 113.4 0.0 9.5e-33 112.4 0.0 1.6 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 EMT52519.1 - 2.8e-23 81.7 0.0 8e-23 80.2 0.0 1.8 1 0 0 1 1 1 1 HRDC domain Helicase_C PF00271.31 EMT52519.1 - 4.8e-21 75.2 0.0 3.5e-18 65.9 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EMT52519.1 - 4e-17 62.7 1.5 4e-17 62.7 1.5 2.3 2 0 0 2 2 2 1 RecQ zinc-binding DEAD PF00270.29 EMT52519.1 - 1.6e-16 60.6 0.0 2.6e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EMT52519.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_Sgs1 PF11408.8 EMT52519.1 - 0.097 12.7 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Sgs1 RecQ helicase MgtC PF02308.16 EMT52520.1 - 1.3e-33 115.9 6.9 1.6e-33 115.6 6.9 1.1 1 0 0 1 1 1 1 MgtC family EF1_GNE PF00736.19 EMT52520.1 - 0.0031 17.7 2.5 0.0053 16.9 2.5 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain PrgI PF12666.7 EMT52520.1 - 0.044 14.5 1.2 0.057 14.1 0.2 1.8 2 0 0 2 2 2 0 PrgI family protein MatE PF01554.18 EMT52521.1 - 3.7e-61 205.5 39.8 1.2e-35 122.6 15.4 2.7 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 EMT52521.1 - 3.6e-09 36.8 16.8 3.6e-09 36.8 16.8 4.3 2 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain MCPsignal PF00015.21 EMT52522.1 - 8.1e-48 162.5 29.4 8.1e-48 162.5 29.4 4.1 3 1 2 5 5 5 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 EMT52522.1 - 2.9e-08 34.0 6.8 3.3e-07 30.6 0.0 4.3 5 1 0 5 5 5 1 HAMP domain DUF948 PF06103.11 EMT52522.1 - 0.05 13.9 29.0 2.3 8.5 0.9 6.4 2 1 4 6 6 6 0 Bacterial protein of unknown function (DUF948) PG_binding_1 PF01471.18 EMT52522.1 - 0.1 12.8 1.0 0.72 10.1 0.1 2.6 2 0 0 2 2 2 0 Putative peptidoglycan binding domain KIP1 PF07765.12 EMT52522.1 - 1.8 8.8 11.1 3 8.0 0.2 4.6 4 1 1 5 5 5 0 KIP1-like protein HTH_3 PF01381.22 EMT52523.1 - 4.8e-08 33.0 0.0 1.1e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 EMT52523.1 - 7.9e-06 26.2 0.0 2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 EMT52523.1 - 8.9e-06 25.6 0.0 3e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 EMT52523.1 - 0.00088 19.2 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain TPR_2 PF07719.17 EMT52523.1 - 0.0082 16.2 0.4 17 5.8 0.3 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat HTH_35 PF13693.6 EMT52523.1 - 0.14 12.2 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding T2SSF PF00482.23 EMT52523.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F TPR_8 PF13181.6 EMT52523.1 - 0.37 11.1 1.4 3.6 8.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMT52523.1 - 0.93 9.4 3.1 15 5.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SpoOE-like PF09388.10 EMT52524.1 - 3.7e-13 49.1 0.6 6e-13 48.5 0.5 1.4 1 1 0 1 1 1 1 Spo0E like sporulation regulatory protein Adenine_deam_C PF13382.6 EMT52525.1 - 6.5e-55 185.0 0.0 1.2e-54 184.2 0.0 1.5 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 EMT52525.1 - 1.1e-18 67.7 0.8 6e-17 62.0 0.5 2.5 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMT52525.1 - 2.8e-13 50.2 0.1 1.2e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Alph_Pro_TM PF09608.10 EMT52525.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) ABC_tran PF00005.27 EMT52526.1 - 9e-34 116.9 0.0 1.6e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 EMT52526.1 - 2.3e-10 40.5 0.0 6.6e-10 39.0 0.0 1.8 2 0 0 2 2 1 1 TOBE domain Rad17 PF03215.15 EMT52526.1 - 8e-05 22.6 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_21 PF13304.6 EMT52526.1 - 0.00012 22.1 1.5 0.41 10.4 0.1 2.7 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMT52526.1 - 0.00076 19.9 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain TOBE PF03459.17 EMT52526.1 - 0.00081 19.6 0.0 0.0023 18.2 0.0 1.8 1 1 0 1 1 1 1 TOBE domain AAA PF00004.29 EMT52526.1 - 0.0027 18.1 0.0 0.0089 16.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMT52526.1 - 0.0063 16.8 0.2 0.011 15.9 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMT52526.1 - 0.013 16.0 1.2 0.019 15.5 1.2 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EMT52526.1 - 0.024 14.6 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 EMT52526.1 - 0.044 13.5 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EMT52526.1 - 0.059 13.1 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain GlcV_C_terminal PF17847.1 EMT52526.1 - 0.1 13.1 0.0 0.29 11.6 0.0 1.9 1 0 0 1 1 1 0 Glucose ABC transporter C-terminal domain AAA_5 PF07728.14 EMT52526.1 - 0.11 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EMT52526.1 - 0.11 12.9 0.1 20 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EMT52526.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 EMT52526.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EMT52526.1 - 0.19 11.3 0.0 1.6 8.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain BPD_transp_1 PF00528.22 EMT52527.1 - 1.4e-14 54.3 19.1 1.4e-14 54.3 19.1 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF983 PF06170.12 EMT52527.1 - 5.9 7.4 13.1 4.8 7.7 1.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF983) BPD_transp_1 PF00528.22 EMT52528.1 - 1.4e-15 57.5 17.2 1.4e-15 57.5 17.2 2.1 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component IU_nuc_hydro PF01156.19 EMT52529.1 - 1.3e-89 300.8 0.3 1.5e-89 300.6 0.3 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SBP_bac_6 PF13343.6 EMT52530.1 - 3e-35 121.8 2.1 4.5e-35 121.2 2.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EMT52530.1 - 3.1e-31 109.2 7.0 3.9e-31 108.9 7.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT52530.1 - 3.5e-23 83.1 7.2 4.8e-23 82.6 7.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EMT52530.1 - 2.9e-15 56.6 0.0 4.3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF2294 PF10057.9 EMT52531.1 - 0.0081 16.3 0.1 0.01 16.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2294) WYL PF13280.6 EMT52533.1 - 9.3e-39 133.2 0.4 1.3e-38 132.8 0.4 1.2 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 EMT52533.1 - 3.8e-13 49.2 0.5 6.7e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 HTH domain HTH_DeoR PF08220.12 EMT52533.1 - 3.3e-06 26.7 0.4 8e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_28 PF13518.6 EMT52533.1 - 0.024 14.8 0.1 0.055 13.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 EMT52533.1 - 0.075 13.1 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DinB_2 PF12867.7 EMT52534.1 - 6.3e-14 52.6 0.3 8.3e-14 52.2 0.3 1.1 1 0 0 1 1 1 1 DinB superfamily DUF1569 PF07606.11 EMT52534.1 - 4.4e-07 30.0 0.1 6.4e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1569) ATP_sub_h PF10775.9 EMT52534.1 - 0.64 10.1 2.5 1.4 8.9 0.1 2.5 3 0 0 3 3 3 0 ATP synthase complex subunit h Lip_prot_lig_C PF10437.9 EMT52535.1 - 1.7e-23 82.4 0.0 4.8e-23 80.9 0.0 1.8 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.19 EMT52535.1 - 5.9e-12 45.6 0.0 1.3e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family EFG_IV PF03764.18 EMT52535.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G, domain IV DUF2196 PF09962.9 EMT52536.1 - 8.4e-33 112.2 2.3 9.7e-33 112.0 2.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Methyltransf_11 PF08241.12 EMT52537.1 - 3.2e-20 72.6 0.0 4.7e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT52537.1 - 2.1e-19 69.8 0.0 3.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT52537.1 - 2.6e-18 66.4 0.0 2.9e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT52537.1 - 2.9e-18 66.4 0.0 4.3e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT52537.1 - 4.1e-15 56.3 0.0 6.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT52537.1 - 2.8e-08 33.4 0.0 3.6e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EMT52537.1 - 3.4e-06 26.7 0.0 5.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EMT52537.1 - 6.4e-05 22.4 0.0 9.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EMT52537.1 - 9.8e-05 21.9 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 EMT52537.1 - 0.00011 21.2 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TPMT PF05724.11 EMT52537.1 - 0.00028 20.6 0.0 0.0048 16.6 0.0 2.0 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Pox_MCEL PF03291.16 EMT52537.1 - 0.00032 19.9 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 2 1 mRNA capping enzyme NNMT_PNMT_TEMT PF01234.17 EMT52537.1 - 0.0033 16.7 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family PCMT PF01135.19 EMT52537.1 - 0.007 16.1 0.0 0.013 15.3 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EMT52537.1 - 0.0082 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TrkA_N PF02254.18 EMT52537.1 - 0.0084 16.4 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N PF00107.26 EMT52537.1 - 0.013 15.4 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AviRa PF11599.8 EMT52537.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa CheR PF01739.18 EMT52537.1 - 0.031 13.8 0.0 0.26 10.8 0.0 2.0 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain LolA_2 PF16584.5 EMT52537.1 - 0.037 13.9 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Methyltransf_24 PF13578.6 EMT52537.1 - 0.042 14.9 0.0 0.065 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EMT52537.1 - 0.044 13.2 0.1 0.53 9.7 0.0 2.3 3 0 0 3 3 3 0 Putative methyltransferase N6_N4_Mtase PF01555.18 EMT52537.1 - 0.045 13.5 0.0 5.1 6.7 0.0 2.1 2 0 0 2 2 2 0 DNA methylase Methyltransf_15 PF09445.10 EMT52537.1 - 0.058 13.0 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EMT52537.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein CarD_CdnL_TRCF PF02559.16 EMT52538.1 - 3.7e-15 56.4 0.0 5.4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 CarD-like/TRCF domain DUF4854 PF16146.5 EMT52539.1 - 0.04 14.2 0.2 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) Chitin_synth_1N PF08407.11 EMT52539.1 - 0.17 11.9 0.7 11 6.1 0.1 2.9 2 1 1 3 3 3 0 Chitin synthase N-terminal Sigma70_r2 PF04542.14 EMT52540.1 - 4.8e-17 61.5 0.1 8.8e-17 60.7 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT52540.1 - 4.3e-10 39.1 0.5 8.9e-10 38.1 0.5 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT52540.1 - 2.3e-05 23.8 0.3 4.5e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sds3 PF08598.11 EMT52540.1 - 0.06 13.3 0.1 0.096 12.7 0.1 1.3 1 0 0 1 1 1 0 Sds3-like Peripla_BP_2 PF01497.18 EMT52541.1 - 2e-26 93.0 0.0 2.6e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein HTH_AraC PF00165.23 EMT52541.1 - 3.6e-23 81.1 0.2 6.9e-11 42.0 0.0 2.9 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EMT52541.1 - 1.1e-18 67.3 0.0 2.4e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 EMT52541.1 - 0.02 14.8 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain HTH_3 PF01381.22 EMT52541.1 - 0.038 14.0 0.1 0.56 10.3 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix Peripla_BP_2 PF01497.18 EMT52542.1 - 1.7e-32 112.9 0.7 3e-32 112.1 0.7 1.3 1 0 0 1 1 1 1 Periplasmic binding protein REC1 PF18501.1 EMT52542.1 - 0.051 13.5 0.6 0.088 12.7 0.6 1.4 1 0 0 1 1 1 0 Alpha helical recognition lobe domain FecCD PF01032.18 EMT52543.1 - 1.7e-85 286.8 30.3 2.5e-85 286.2 30.3 1.2 1 0 0 1 1 1 1 FecCD transport family FecCD PF01032.18 EMT52544.1 - 4.2e-87 292.1 25.9 5e-87 291.8 25.9 1.0 1 0 0 1 1 1 1 FecCD transport family Deltameth_res PF16020.5 EMT52544.1 - 0.049 13.5 0.3 0.049 13.5 0.3 2.4 2 0 0 2 2 2 0 Deltamethrin resistance DUF3165 PF11364.8 EMT52544.1 - 5 7.5 6.5 2.4 8.5 1.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3165) Esterase PF00756.20 EMT52545.1 - 1e-22 81.0 0.0 2e-22 80.1 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EMT52545.1 - 2.3e-06 27.3 0.0 1e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EMT52545.1 - 0.00017 20.9 0.0 0.00038 19.8 0.0 1.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMT52545.1 - 0.031 14.9 0.2 0.1 13.2 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMT52545.1 - 0.04 13.6 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EMT52545.1 - 0.084 12.7 0.0 11 5.8 0.0 2.2 1 1 0 2 2 2 0 alpha/beta hydrolase fold LCAT PF02450.15 EMT52545.1 - 0.23 10.6 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase BPD_transp_1 PF00528.22 EMT52546.1 - 4.3e-24 85.3 18.8 4.3e-24 85.3 18.8 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EMT52547.1 - 2.3e-30 105.9 0.0 3.9e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT52547.1 - 9.2e-07 29.0 2.0 0.008 16.0 0.1 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EMT52547.1 - 3.5e-06 27.0 0.1 7.5e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EMT52547.1 - 0.00012 21.8 0.1 0.00031 20.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT52547.1 - 0.00015 22.1 0.1 0.00096 19.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EMT52547.1 - 0.00028 21.3 0.1 0.0018 18.7 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT52547.1 - 0.00056 20.3 0.0 0.00085 19.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EMT52547.1 - 0.00068 19.4 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_23 PF13476.6 EMT52547.1 - 0.001 19.6 0.6 0.002 18.7 0.2 1.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 EMT52547.1 - 0.001 18.5 0.1 0.44 9.9 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EMT52547.1 - 0.0048 16.8 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain ATPase_2 PF01637.18 EMT52547.1 - 0.0052 16.7 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 EMT52547.1 - 0.012 14.5 0.2 0.5 9.1 0.0 2.8 2 1 1 3 3 3 0 Predicted ATPase of the ABC class AAA_15 PF13175.6 EMT52547.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain Adeno_IVa2 PF02456.15 EMT52547.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein MMR_HSR1 PF01926.23 EMT52547.1 - 0.022 14.8 0.7 0.12 12.5 0.7 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EMT52547.1 - 0.025 14.6 0.4 0.15 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EMT52547.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMT52547.1 - 0.029 14.8 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 EMT52547.1 - 0.035 13.2 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EMT52547.1 - 0.048 13.9 0.4 0.24 11.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 EMT52547.1 - 0.06 12.5 0.1 3.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.22 EMT52547.1 - 0.087 12.0 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 EMT52547.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EMT52547.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EMT52547.1 - 0.1 12.8 0.8 0.27 11.4 0.3 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EMT52547.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMT52547.1 - 0.11 12.3 0.3 0.38 10.7 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_27 PF13514.6 EMT52547.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMT52547.1 - 0.14 11.4 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.6 EMT52547.1 - 0.15 12.3 0.2 0.39 11.0 0.2 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 EMT52547.1 - 0.16 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NMT1 PF09084.11 EMT52548.1 - 2.3e-21 76.7 0.5 3.6e-21 76.1 0.5 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EMT52548.1 - 2.8e-19 69.8 0.1 4.2e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 EMT52548.1 - 2.9e-13 49.8 0.0 8.1e-13 48.3 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EMT52548.1 - 7.4e-11 42.1 0.1 1.6e-10 41.0 0.1 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Lipoprotein_9 PF03180.14 EMT52548.1 - 0.00057 19.1 0.0 0.0014 17.8 0.0 1.8 1 1 0 1 1 1 1 NLPA lipoprotein NMT1_3 PF16868.5 EMT52548.1 - 0.00065 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 NMT1-like family DUF4990 PF16380.5 EMT52548.1 - 0.0039 17.3 0.1 0.0084 16.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function Alba PF01918.21 EMT52548.1 - 0.021 14.6 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Alba DUF3834 PF12916.7 EMT52548.1 - 0.034 13.4 0.4 0.22 10.7 0.0 2.3 1 1 1 3 3 3 0 Protein of unknown function (DUF3834) dCache_1 PF02743.18 EMT52548.1 - 0.061 13.1 0.1 0.64 9.8 0.1 2.1 1 1 0 1 1 1 0 Cache domain DUF1572 PF07609.11 EMT52549.1 - 5e-15 55.7 0.0 1.2e-14 54.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1572) DinB PF05163.12 EMT52549.1 - 2.3e-09 37.4 0.0 4.8e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 DinB family DinB_2 PF12867.7 EMT52549.1 - 4.7e-09 36.8 0.0 6.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 EMT52549.1 - 1.2e-08 35.5 0.0 1.5e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF664) MDMPI_N PF11716.8 EMT52549.1 - 0.0092 16.7 0.0 0.074 13.7 0.0 2.0 1 1 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain TPM_phosphatase PF04536.14 EMT52550.1 - 6.8e-09 36.0 0.5 2.6e-08 34.1 0.1 2.3 2 0 0 2 2 2 1 TPM domain MCPsignal PF00015.21 EMT52550.1 - 0.0036 17.1 0.8 0.0036 17.1 0.8 5.1 4 1 1 5 5 5 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Cation_ATPase PF13246.6 EMT52550.1 - 0.037 14.1 0.2 0.13 12.4 0.2 1.9 1 0 0 1 1 1 0 Cation transport ATPase (P-type) COX4 PF02936.14 EMT52550.1 - 0.052 13.6 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF211 PF02680.14 EMT52550.1 - 0.1 12.8 0.0 0.41 10.8 0.0 2.1 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 SOG2 PF10428.9 EMT52550.1 - 0.31 10.2 11.6 0.03 13.6 5.4 2.2 2 1 1 3 3 3 0 RAM signalling pathway protein DUF3618 PF12277.8 EMT52550.1 - 1.3 9.3 5.9 33 4.8 0.2 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) Fzo_mitofusin PF04799.13 EMT52550.1 - 3.5 7.2 14.3 0.2 11.2 1.9 4.3 4 1 1 5 5 5 0 fzo-like conserved region FUSC PF04632.12 EMT52550.1 - 5.1 5.5 27.2 0.013 14.0 3.2 3.4 1 1 2 3 3 3 0 Fusaric acid resistance protein family DUF4363 PF14276.6 EMT52550.1 - 5.2 7.2 10.4 0.77 9.9 0.1 4.6 5 1 1 6 6 6 0 Domain of unknown function (DUF4363) BLOC1_2 PF10046.9 EMT52550.1 - 8.8 6.7 23.9 6.5 7.1 0.6 5.9 4 3 3 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 adh_short_C2 PF13561.6 EMT52551.1 - 6.3e-61 205.9 3.4 7.8e-61 205.6 3.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT52551.1 - 1.5e-55 187.7 1.0 1.8e-55 187.4 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT52551.1 - 2e-13 50.7 0.8 3.2e-13 50.0 0.8 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMT52551.1 - 0.0049 16.8 0.1 0.0086 16.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EMT52551.1 - 0.0069 15.9 0.5 0.011 15.2 0.5 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EMT52551.1 - 0.04 14.2 0.4 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EMT52551.1 - 0.053 13.8 0.1 0.098 12.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain TRM PF02005.16 EMT52551.1 - 0.057 12.6 0.5 0.8 8.8 0.0 2.3 1 1 1 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase NmrA PF05368.13 EMT52551.1 - 0.069 12.7 0.6 0.31 10.6 0.2 2.1 1 1 1 3 3 3 0 NmrA-like family ADH_zinc_N PF00107.26 EMT52551.1 - 0.085 12.8 0.1 1.5 8.8 0.1 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase SBF PF01758.16 EMT52552.1 - 9.8e-24 84.1 12.8 9.8e-24 84.1 12.8 1.8 1 1 1 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 EMT52552.1 - 2.9e-18 66.2 17.2 3.2e-18 66.1 16.6 1.3 1 1 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Pyr_redox_2 PF07992.14 EMT52553.1 - 8.9e-75 251.6 1.2 1.1e-74 251.4 1.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EMT52553.1 - 1e-32 112.6 0.3 3e-32 111.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EMT52553.1 - 4e-23 81.8 5.0 4.9e-20 71.9 0.2 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT52553.1 - 3.7e-18 65.8 0.3 2.8e-17 63.0 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMT52553.1 - 7.6e-10 38.9 1.6 0.00015 21.9 0.4 2.8 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMT52553.1 - 2.6e-08 33.0 11.9 0.00013 20.8 0.5 3.9 3 1 1 4 4 4 3 HI0933-like protein GIDA PF01134.22 EMT52553.1 - 4.4e-08 32.6 9.0 2.3e-06 27.0 0.5 3.4 3 1 1 4 4 4 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EMT52553.1 - 1.5e-07 31.1 8.2 1.1e-06 28.3 0.4 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMT52553.1 - 6.2e-06 25.7 2.3 0.051 12.9 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EMT52553.1 - 7.9e-06 25.7 17.9 0.1 12.2 3.4 4.9 5 0 0 5 5 5 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EMT52553.1 - 2.3e-05 24.8 0.3 0.1 13.0 0.1 2.7 2 1 0 2 2 2 2 Putative NAD(P)-binding 3HCDH_N PF02737.18 EMT52553.1 - 5.7e-05 23.1 0.3 5.7e-05 23.1 0.3 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EMT52553.1 - 7.1e-05 22.1 1.8 7.1e-05 22.1 1.8 3.7 4 0 0 4 4 4 1 FAD binding domain Lycopene_cycl PF05834.12 EMT52553.1 - 0.00013 21.2 3.3 0.41 9.6 0.0 3.2 2 1 1 3 3 3 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 EMT52553.1 - 0.00019 20.8 4.9 0.15 11.2 0.2 2.4 2 1 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 EMT52553.1 - 0.00057 18.8 5.5 0.025 13.5 0.2 3.1 3 0 0 3 3 3 1 Tryptophan halogenase 2-Hacid_dh_C PF02826.19 EMT52553.1 - 0.0072 15.7 0.5 0.052 12.9 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 EMT52553.1 - 0.0098 15.1 0.0 0.021 14.0 0.0 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) XdhC_C PF13478.6 EMT52553.1 - 0.042 14.4 0.0 1.8 9.1 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain Amino_oxidase PF01593.24 EMT52553.1 - 0.072 12.4 0.1 0.34 10.1 0.0 2.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EMT52553.1 - 0.086 12.8 13.6 1.9 8.4 0.0 4.3 3 1 1 4 4 4 0 FAD-NAD(P)-binding TFIIA_gamma_N PF02268.16 EMT52553.1 - 0.11 12.5 0.3 0.43 10.6 0.0 2.1 3 0 0 3 3 2 0 Transcription initiation factor IIA, gamma subunit, helical domain UDPG_MGDP_dh_N PF03721.14 EMT52553.1 - 0.25 10.9 1.0 0.83 9.2 0.0 2.3 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EMT52553.1 - 2.7 8.3 5.4 5.2 7.4 0.2 3.3 3 1 1 4 4 3 0 TrkA-N domain 2-oxoacid_dh PF00198.23 EMT52554.1 - 8.9e-86 287.1 0.1 1.1e-85 286.8 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EMT52554.1 - 3.6e-17 62.0 0.2 8.5e-17 60.8 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EMT52554.1 - 1.2e-15 57.6 1.7 5.5e-10 39.4 0.6 2.7 2 0 0 2 2 2 2 e3 binding domain ATP-gua_Ptrans PF00217.19 EMT52554.1 - 0.038 13.5 0.1 0.62 9.5 0.0 2.1 1 1 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain Transket_pyr PF02779.24 EMT52555.1 - 6.7e-47 159.5 0.1 4.1e-46 156.9 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMT52555.1 - 3.7e-39 133.4 0.2 8.6e-39 132.2 0.2 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EMT52555.1 - 0.085 13.2 0.1 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II E1_dh PF00676.20 EMT52556.1 - 2.9e-95 318.7 0.0 3.3e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EMT52556.1 - 1.3e-06 28.3 1.0 4.7e-06 26.5 1.0 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EMT52556.1 - 7.8e-05 22.0 0.0 0.00022 20.6 0.0 1.6 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 EMT52556.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain FERM_M PF00373.18 EMT52556.1 - 0.18 12.2 0.0 0.27 11.7 0.0 1.2 1 0 0 1 1 1 0 FERM central domain DUF5320 PF17253.2 EMT52556.1 - 6.7 7.8 11.8 18 6.5 4.2 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5320) Aminotran_1_2 PF00155.21 EMT52557.1 - 7.3e-28 97.8 0.0 1.1e-27 97.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EMT52557.1 - 5.1e-17 61.3 0.2 1.4e-16 59.9 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 EMT52557.1 - 1.3e-06 27.5 0.0 4.6e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DctM PF06808.12 EMT52558.1 - 6.7e-118 394.1 57.3 7.6e-118 393.9 57.3 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component DUF2583 PF10762.9 EMT52558.1 - 0.018 15.5 0.8 0.018 15.5 0.8 3.5 4 1 2 6 6 6 0 Protein of unknown function (DUF2583) P5CR_dimer PF14748.6 EMT52558.1 - 0.027 14.7 1.0 0.1 12.8 1.0 2.0 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation CitMHS PF03600.16 EMT52558.1 - 0.068 12.4 65.3 2.7 7.1 37.8 2.3 1 1 1 2 2 2 0 Citrate transporter DcuC PF03606.15 EMT52558.1 - 0.55 8.6 45.5 19 3.5 45.4 2.2 1 1 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DctQ PF04290.12 EMT52559.1 - 3.1e-32 111.3 8.1 4.1e-32 110.9 8.1 1.1 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component Bac_export_2 PF01312.19 EMT52559.1 - 0.04 13.1 3.4 0.044 13.0 2.0 1.6 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family DUF2070 PF09843.9 EMT52559.1 - 0.22 9.8 5.8 0.27 9.5 5.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FtsX PF02687.21 EMT52559.1 - 1.4 9.5 7.2 1.2 9.6 2.4 2.2 2 0 0 2 2 2 0 FtsX-like permease family DUF4818 PF16089.5 EMT52559.1 - 4.7 7.7 12.8 6.2 7.3 1.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4818) Cation_ATPase_C PF00689.21 EMT52559.1 - 7.4 6.2 11.6 1.2 8.8 1.9 2.4 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Syndecan PF01034.20 EMT52559.1 - 8 6.5 5.8 1.8 8.5 0.4 2.3 2 0 0 2 2 2 0 Syndecan domain DctP PF03480.13 EMT52560.1 - 2e-93 312.8 1.7 2.5e-93 312.5 1.7 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 NMT1 PF09084.11 EMT52560.1 - 0.075 13.0 0.0 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 NMT1/THI5 like NDUF_B5 PF09781.9 EMT52560.1 - 0.13 11.9 0.7 0.24 11.0 0.7 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit UbiA PF01040.18 EMT52561.1 - 1e-23 84.0 16.2 1e-23 84.0 16.2 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Multi_Drug_Res PF00893.19 EMT52562.1 - 6.8e-09 36.3 9.5 2.4e-08 34.5 9.5 1.8 1 1 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 EMT52562.1 - 7.7e-06 26.1 14.7 2.4e-05 24.5 14.3 1.8 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EMT52562.1 - 0.0019 18.2 3.5 0.002 18.1 3.5 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 TPT PF03151.16 EMT52562.1 - 0.012 15.0 6.0 0.021 14.2 6.0 1.5 1 1 0 1 1 1 0 Triose-phosphate Transporter family Sugar_transport PF06800.12 EMT52562.1 - 0.033 13.5 7.6 0.041 13.2 7.6 1.1 1 0 0 1 1 1 0 Sugar transport protein TcpE PF12648.7 EMT52562.1 - 0.11 13.0 3.8 0.15 12.6 1.9 1.9 2 0 0 2 2 2 0 TcpE family Phage_holin_3_5 PF16085.5 EMT52562.1 - 0.14 12.3 3.6 0.11 12.6 2.3 1.6 1 1 0 1 1 1 0 Bacteriophage holin Hol, superfamily III DUF4536 PF15055.6 EMT52562.1 - 2.7 8.3 6.3 3 8.2 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DUF202 PF02656.15 EMT52562.1 - 4.3 7.8 13.1 0.81 10.2 3.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF212 PF02681.14 EMT52563.1 - 3.8e-30 104.7 0.3 4.5e-30 104.4 0.3 1.0 1 0 0 1 1 1 1 Divergent PAP2 family PAP2 PF01569.21 EMT52563.1 - 0.0028 17.4 0.8 0.16 11.7 0.1 2.4 2 1 0 2 2 2 2 PAP2 superfamily Caroten_synth PF04240.12 EMT52563.1 - 0.074 12.9 0.1 0.15 11.9 0.1 1.6 1 1 0 1 1 1 0 Carotenoid biosynthesis protein Glucos_trans_II PF14264.6 EMT52564.1 - 0.00044 19.7 20.2 0.00044 19.7 20.2 2.8 2 1 0 2 2 2 1 Glucosyl transferase GtrII Lactamase_B PF00753.27 EMT52565.1 - 1.4e-24 87.2 1.4 3e-24 86.1 1.4 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMT52565.1 - 8.1e-05 22.2 0.0 0.00017 21.2 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EMT52565.1 - 0.0054 16.2 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain G3P_antiterm PF04309.12 EMT52566.1 - 8.4e-60 201.1 0.1 1e-59 200.9 0.1 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 EMT52566.1 - 0.0026 16.9 0.0 0.0066 15.6 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) NMO PF03060.15 EMT52566.1 - 0.0048 16.3 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 EMT52566.1 - 0.0059 15.7 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EMT52566.1 - 0.095 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein AP_endonuc_2 PF01261.24 EMT52567.1 - 8.7e-30 103.7 0.1 1e-29 103.5 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel UvdE PF03851.14 EMT52567.1 - 0.022 14.0 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 UV-endonuclease UvdE BPD_transp_1 PF00528.22 EMT52568.1 - 7.6e-19 68.2 10.9 7.6e-19 68.2 10.9 1.6 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component NADH_B2 PF14813.6 EMT52568.1 - 1.9 8.3 5.1 0.31 10.9 0.2 2.1 2 0 0 2 2 2 0 NADH dehydrogenase 1 beta subcomplex subunit 2 BPD_transp_1 PF00528.22 EMT52569.1 - 2.8e-22 79.4 14.1 2.8e-22 79.4 14.1 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_8 PF13416.6 EMT52570.1 - 6.4e-54 183.7 12.2 8.8e-54 183.2 12.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT52570.1 - 1.6e-40 140.0 14.7 1.6e-40 140.0 14.7 1.7 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EMT52570.1 - 7.9e-08 32.0 0.4 0.007 15.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein ABC_tran PF00005.27 EMT52571.1 - 1.8e-31 109.5 0.0 3.1e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 EMT52571.1 - 2e-09 38.1 0.1 7.2e-09 36.4 0.1 2.0 1 0 0 1 1 1 1 MalK OB fold domain AAA_21 PF13304.6 EMT52571.1 - 2.3e-07 30.9 0.1 0.021 14.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT52571.1 - 1e-06 28.3 0.1 4.4e-06 26.3 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain TOBE_2 PF08402.10 EMT52571.1 - 5.2e-05 23.3 0.1 0.001 19.2 0.1 2.6 1 1 0 1 1 1 1 TOBE domain RsgA_GTPase PF03193.16 EMT52571.1 - 0.0028 17.6 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 EMT52571.1 - 0.0039 17.1 0.1 0.011 15.7 0.1 1.6 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 EMT52571.1 - 0.0063 16.8 0.1 0.013 15.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT52571.1 - 0.012 16.0 0.1 0.022 15.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain TOBE PF03459.17 EMT52571.1 - 0.013 15.7 0.3 0.06 13.7 0.2 2.1 2 0 0 2 2 2 0 TOBE domain MIT_C PF16565.5 EMT52571.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT AAA_29 PF13555.6 EMT52571.1 - 0.037 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EMT52571.1 - 0.042 13.4 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMT52571.1 - 0.048 13.9 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EMT52571.1 - 0.052 14.0 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EMT52571.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EMT52571.1 - 0.08 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain CysA_C_terminal PF17850.1 EMT52571.1 - 0.1 13.2 0.2 0.41 11.2 0.0 2.2 2 0 0 2 2 1 0 CysA C-terminal regulatory domain AAA_23 PF13476.6 EMT52571.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Hydrolase_6 PF13344.6 EMT52572.1 - 2.2e-24 85.5 0.0 5.1e-24 84.3 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMT52572.1 - 2.8e-20 72.1 0.0 1.2e-19 70.1 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 EMT52572.1 - 3.7e-07 30.4 0.6 9e-06 25.9 0.0 2.7 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMT52572.1 - 4.7e-06 27.0 2.1 0.00029 21.2 2.1 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EMT52572.1 - 0.0015 18.1 0.0 0.035 13.7 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase DUF2608 PF11019.8 EMT52572.1 - 0.23 10.9 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Topoisom_bac PF01131.20 EMT52573.1 - 4.6e-119 398.1 2.9 6.4e-119 397.6 2.9 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EMT52573.1 - 2.8e-16 59.6 0.3 1.7e-13 50.7 0.0 3.1 3 0 0 3 3 3 1 Toprim domain zf-C4_Topoisom PF01396.19 EMT52573.1 - 0.018 14.8 10.3 0.066 13.0 3.4 2.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn-ribbon_8 PF09723.10 EMT52573.1 - 0.12 12.5 4.8 3.5 7.8 1.4 3.0 3 0 0 3 3 3 0 Zinc ribbon domain tRNA-synt_1g PF09334.11 EMT52573.1 - 0.29 9.8 5.5 0.18 10.5 3.5 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (M) zf-ISL3 PF14690.6 EMT52573.1 - 0.32 11.7 5.3 3.3 8.5 1.4 2.8 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc-ribbons_6 PF07191.12 EMT52573.1 - 0.44 10.5 7.3 0.86 9.6 7.3 1.5 1 0 0 1 1 1 0 zinc-ribbons DUF2387 PF09526.10 EMT52573.1 - 0.71 10.1 4.9 0.19 11.9 1.1 2.0 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) PADR1 PF08063.12 EMT52573.1 - 7 6.5 6.2 21 5.0 0.4 2.4 2 0 0 2 2 2 0 PADR1 (NUC008) domain HATPase_c PF02518.26 EMT52574.1 - 1.6e-43 147.8 0.9 7.2e-31 107.0 0.1 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMT52574.1 - 8.2e-29 100.0 0.0 1.7e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain His_kinase PF06580.13 EMT52574.1 - 2.4e-22 79.0 0.3 7.8e-22 77.4 0.3 2.0 1 0 0 1 1 1 1 Histidine kinase 7TMR-DISM_7TM PF07695.11 EMT52574.1 - 1.6e-10 41.2 24.8 1.6e-10 41.2 24.8 2.2 2 0 0 2 2 2 1 7TM diverse intracellular signalling HisKA PF00512.25 EMT52574.1 - 1.1e-09 38.1 0.6 1.1e-09 38.1 0.6 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EMT52574.1 - 4.1e-08 33.2 0.0 0.0008 19.4 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EMT52574.1 - 4.5e-06 26.5 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EMT52574.1 - 0.013 15.3 0.0 0.17 11.8 0.0 2.6 3 0 0 3 3 3 0 GHKL domain SdrD_B PF17210.3 EMT52575.1 - 4.5e-165 538.9 34.2 1.8e-34 118.3 1.2 5.6 5 0 0 5 5 5 5 SdrD B-like domain CarboxypepD_reg PF13620.6 EMT52575.1 - 1.6e-28 98.8 13.5 3.4e-05 24.0 0.0 7.2 6 0 0 6 6 6 5 Carboxypeptidase regulatory-like domain DUF11 PF01345.18 EMT52575.1 - 5.5e-18 65.1 6.1 5.4e-07 29.8 0.0 6.3 6 0 0 6 6 5 4 Domain of unknown function DUF11 CarbopepD_reg_2 PF13715.6 EMT52575.1 - 4e-06 26.8 9.1 0.2 11.7 0.0 6.2 6 0 0 6 6 6 1 CarboxypepD_reg-like domain Gram_pos_anchor PF00746.21 EMT52575.1 - 3.6e-05 23.6 0.0 7.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 LPXTG cell wall anchor motif PPC PF04151.15 EMT52575.1 - 0.0011 20.0 23.6 0.34 12.1 1.0 6.9 6 0 0 6 6 6 2 Bacterial pre-peptidase C-terminal domain Cna_B PF05738.13 EMT52575.1 - 0.0012 19.4 11.1 0.45 11.1 0.0 7.7 8 2 1 9 9 8 1 Cna protein B-type domain bMG3 PF11974.8 EMT52575.1 - 0.014 15.4 0.6 9.8 6.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial alpha-2-macroglobulin MG3 domain muHD PF10291.9 EMT52575.1 - 0.023 14.2 0.1 0.058 12.8 0.1 1.6 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain SpaA PF17802.1 EMT52575.1 - 0.078 13.3 44.9 0.083 13.2 0.3 9.0 9 1 1 10 10 9 0 Prealbumin-like fold domain Big_8 PF17961.1 EMT52575.1 - 1.3 9.2 10.0 5.7 7.1 0.3 4.5 4 0 0 4 4 4 0 Bacterial Ig domain Y_Y_Y PF07495.13 EMT52575.1 - 2.1 8.4 6.2 5.4 7.0 0.1 4.0 4 0 0 4 4 4 0 Y_Y_Y domain P_gingi_FimA PF06321.11 EMT52575.1 - 6.7 6.8 8.5 15 5.7 0.2 4.1 3 0 0 3 3 3 0 Major fimbrial subunit protein (FimA) CopC PF04234.12 EMT52575.1 - 8.2 7.5 8.5 1e+02 4.0 0.0 6.0 8 1 1 9 9 4 0 CopC domain Sortase PF04203.13 EMT52576.1 - 4.1e-28 97.7 0.0 5.3e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Sortase domain 7tm_7 PF08395.12 EMT52576.1 - 0.0084 15.4 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor Cupin_2 PF07883.11 EMT52576.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Response_reg PF00072.24 EMT52577.1 - 1.4e-28 99.3 0.8 1.5e-28 99.2 0.8 1.0 1 0 0 1 1 1 1 Response regulator receiver domain PH_13 PF16652.5 EMT52577.1 - 0.01 15.7 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain TadZ_N PF16968.5 EMT52577.1 - 0.087 12.5 0.1 0.093 12.4 0.1 1.3 1 1 0 1 1 1 0 Pilus assembly protein TadZ N-terminal Response_reg PF00072.24 EMT52578.1 - 4.4e-14 52.6 0.0 1e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain BTAD PF03704.17 EMT52578.1 - 5.7e-12 46.3 0.3 1.2e-11 45.2 0.3 1.5 1 0 0 1 1 1 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 EMT52578.1 - 4.4e-05 23.5 0.0 0.00015 21.8 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FYVE_2 PF02318.16 EMT52578.1 - 0.039 14.2 0.2 0.065 13.4 0.2 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger TPR_14 PF13428.6 EMT52578.1 - 0.089 13.7 0.0 1 10.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Response_reg PF00072.24 EMT52579.1 - 1.9e-05 24.8 0.0 1.9e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Polysacc_deac_1 PF01522.21 EMT52580.1 - 1.5e-56 189.6 0.3 6.8e-29 100.3 0.1 2.3 2 0 0 2 2 2 2 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EMT52580.1 - 2e-05 23.9 1.5 0.19 10.9 0.3 3.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 57 UDPG_MGDP_dh_N PF03721.14 EMT52581.1 - 1.6e-35 122.4 0.1 3.1e-35 121.5 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EMT52581.1 - 1.1e-24 86.5 0.1 2.1e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EMT52581.1 - 2e-18 66.7 0.0 5.7e-18 65.3 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain IF2_N PF04760.15 EMT52581.1 - 0.0024 17.6 0.7 7 6.6 0.0 4.1 4 0 0 4 4 4 1 Translation initiation factor IF-2, N-terminal region NAD_binding_2 PF03446.15 EMT52581.1 - 0.0028 17.8 0.0 0.019 15.1 0.0 2.4 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glycos_transf_2 PF00535.26 EMT52582.1 - 1.8e-34 119.0 0.0 3.8e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMT52582.1 - 2.4e-29 102.8 0.0 3.6e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 EMT52582.1 - 3.8e-22 78.6 10.3 3.8e-22 78.6 10.3 3.7 2 1 1 3 3 3 1 Chitin synthase Glyco_transf_21 PF13506.6 EMT52582.1 - 3.5e-11 42.9 0.2 1.7e-10 40.6 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 21 PilZ PF07238.14 EMT52582.1 - 1.7e-06 28.3 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 PilZ domain Glyco_tranf_2_2 PF10111.9 EMT52582.1 - 1.4e-05 24.8 0.1 3.1e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EMT52582.1 - 2.4e-05 24.3 16.8 0.00042 20.3 9.2 3.0 3 1 0 3 3 3 2 Glycosyl transferase family group 2 Osmo_MPGsynth PF09488.10 EMT52582.1 - 0.09 11.5 0.5 2 7.0 0.5 2.2 1 1 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) RIG-I_C PF18119.1 EMT52582.1 - 0.13 12.3 0.4 13 5.8 0.1 2.4 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain CDH1_2_SANT_HL1 PF18375.1 EMT52582.1 - 0.14 12.8 0.0 0.45 11.2 0.0 1.8 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 Glyco_tranf_2_4 PF13704.6 EMT52582.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 Polysacc_deac_1 PF01522.21 EMT52583.1 - 4.4e-05 23.4 0.0 9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase HTH_5 PF01022.20 EMT52583.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Glyco_hydro_18 PF00704.28 EMT52584.1 - 4.6e-10 39.7 0.0 8.5e-10 38.9 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 RHH_3 PF12651.7 EMT52584.1 - 0.057 13.4 0.5 1.5 8.8 0.1 2.7 2 0 0 2 2 2 0 Ribbon-helix-helix domain FliT PF05400.13 EMT52584.1 - 0.081 13.7 1.7 5.4 7.9 0.0 3.5 4 0 0 4 4 4 0 Flagellar protein FliT adh_short_C2 PF13561.6 EMT52585.1 - 2.9e-58 197.2 0.1 3.4e-58 197.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT52585.1 - 1.1e-53 181.6 0.3 1.3e-53 181.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT52585.1 - 3.4e-07 30.3 0.1 5.1e-07 29.8 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMT52585.1 - 0.011 15.2 0.9 0.025 14.0 0.1 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family TauE PF01925.19 EMT52586.1 - 2.4e-30 105.9 23.2 2.9e-30 105.7 23.2 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Pep_deformylase PF01327.21 EMT52587.1 - 2.6e-46 157.1 0.0 3.2e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase HTH_26 PF13443.6 EMT52588.1 - 8.5e-22 77.4 0.0 9.7e-22 77.2 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_31 PF13560.6 EMT52588.1 - 1.8e-05 25.0 0.1 2.1e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_33 PF13592.6 EMT52588.1 - 0.00032 20.3 0.0 0.0006 19.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_3 PF01381.22 EMT52588.1 - 0.049 13.7 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix BacA PF02673.18 EMT52589.1 - 3.4e-80 269.5 13.7 3.9e-80 269.2 13.7 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA Penicillinase_R PF03965.16 EMT52590.1 - 2e-36 124.9 0.1 2.3e-36 124.7 0.1 1.0 1 0 0 1 1 1 1 Penicillinase repressor DUF3489 PF11994.8 EMT52590.1 - 0.0024 17.9 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3489) SMC_ScpB PF04079.16 EMT52590.1 - 0.014 15.0 0.1 0.038 13.6 0.0 1.7 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB MarR PF01047.22 EMT52590.1 - 0.028 14.4 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 MarR family PaaX PF07848.12 EMT52590.1 - 0.035 14.3 0.0 0.052 13.8 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein ANAPC2 PF08672.11 EMT52590.1 - 0.13 12.8 0.6 6.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Peptidase_M56 PF05569.11 EMT52591.1 - 1.4e-54 185.3 1.7 2.4e-53 181.3 1.7 2.1 1 1 0 1 1 1 1 BlaR1 peptidase M56 Peptidase_M48 PF01435.18 EMT52591.1 - 0.0027 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF4367 PF14285.6 EMT52591.1 - 0.0036 17.7 3.5 0.0036 17.7 3.5 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4367) DUF4179 PF13786.6 EMT52591.1 - 0.17 12.4 2.6 2.4 8.7 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) Peripla_BP_2 PF01497.18 EMT52592.1 - 3.2e-35 121.8 0.3 3.9e-35 121.5 0.3 1.1 1 0 0 1 1 1 1 Periplasmic binding protein FecCD PF01032.18 EMT52593.1 - 7.1e-94 314.3 30.5 8.5e-94 314.1 30.5 1.0 1 0 0 1 1 1 1 FecCD transport family FecCD PF01032.18 EMT52594.1 - 1.9e-95 319.5 37.0 2.3e-95 319.2 37.0 1.0 1 0 0 1 1 1 1 FecCD transport family PALP PF00291.25 EMT52595.1 - 2.4e-59 201.2 0.0 2.8e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme VirE2 PF07229.12 EMT52595.1 - 0.05 12.3 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 VirE2 OCD_Mu_crystall PF02423.15 EMT52596.1 - 1.9e-62 211.0 0.2 2.4e-62 210.7 0.2 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EMT52596.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 EMT52596.1 - 0.0022 18.8 0.0 0.0063 17.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EMT52596.1 - 0.025 14.8 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain IucA_IucC PF04183.12 EMT52597.1 - 6.2e-51 173.3 0.0 9.5e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 EMT52597.1 - 2.1e-35 122.6 0.2 4.4e-35 121.5 0.2 1.5 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter IucA_IucC PF04183.12 EMT52598.1 - 1.7e-75 253.6 0.0 2.6e-75 253.1 0.0 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 EMT52598.1 - 3.6e-32 112.0 0.9 7.8e-32 110.9 0.9 1.6 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter SUZ PF12752.7 EMT52598.1 - 5.8 7.8 5.5 2.2 9.1 1.3 2.5 3 0 0 3 3 3 0 SUZ domain Orn_Arg_deC_N PF02784.16 EMT52599.1 - 3.5e-32 111.7 0.0 4.4e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EMT52599.1 - 2.4e-16 59.8 0.0 2.9e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 EMT52599.1 - 7.2e-08 32.3 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain ParBc PF02195.18 EMT52600.1 - 2.3e-11 43.8 0.0 4.6e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 ParB-like nuclease domain CCG PF02754.16 EMT52601.1 - 1.1e-31 108.9 6.4 3.8e-16 59.1 1.1 2.6 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 EMT52601.1 - 4e-14 52.8 4.4 1.1e-13 51.4 4.4 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EMT52601.1 - 8.8e-13 48.6 4.0 3e-12 46.9 4.0 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EMT52601.1 - 3.6e-12 46.7 5.1 1.1e-11 45.1 5.1 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 EMT52601.1 - 2.2e-09 36.8 12.7 0.00016 21.3 2.6 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 EMT52601.1 - 2.3e-09 36.9 11.2 2.9e-05 23.9 2.0 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EMT52601.1 - 5.6e-09 36.0 4.8 1.7e-08 34.5 4.8 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EMT52601.1 - 4.4e-08 32.8 12.5 0.0011 18.9 2.7 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EMT52601.1 - 7.1e-08 32.4 8.1 6.4e-06 26.2 9.9 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EMT52601.1 - 2.9e-07 31.3 5.2 1.4e-06 29.1 5.3 2.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 EMT52601.1 - 3.5e-06 27.1 10.6 0.0027 18.1 1.6 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 EMT52601.1 - 0.00058 20.7 5.1 0.48 11.3 0.2 3.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 EMT52601.1 - 0.00072 19.6 12.1 0.033 14.3 12.3 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 EMT52601.1 - 0.00078 19.6 6.0 0.32 11.2 0.4 2.7 1 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 EMT52601.1 - 0.011 16.6 19.6 0.097 13.7 5.7 3.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 EMT52601.1 - 0.051 14.3 2.5 4.6 8.0 0.1 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 EMT52601.1 - 0.15 12.6 6.5 2.8 8.6 0.7 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I FAD-oxidase_C PF02913.19 EMT52602.1 - 7.3e-76 255.1 0.2 9.5e-76 254.7 0.2 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMT52602.1 - 1.9e-41 141.1 0.0 3.4e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain TMF_TATA_bd PF12325.8 EMT52602.1 - 0.081 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding H2TH PF06831.14 EMT52602.1 - 0.097 12.7 0.0 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase H2TH domain FCD PF07729.12 EMT52603.1 - 6e-24 84.9 5.7 8.5e-24 84.4 5.7 1.2 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EMT52603.1 - 2e-20 72.2 2.0 3.2e-20 71.5 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 EMT52603.1 - 0.0099 16.2 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator FadR_C PF07840.12 EMT52603.1 - 0.013 15.4 0.1 0.018 14.9 0.1 1.2 1 0 0 1 1 1 0 FadR C-terminal domain HTH_41 PF14502.6 EMT52603.1 - 0.016 14.9 0.0 0.061 13.0 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_CodY PF08222.11 EMT52603.1 - 0.029 13.9 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_11 PF08279.12 EMT52603.1 - 0.05 13.6 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 HTH domain HTH_Crp_2 PF13545.6 EMT52603.1 - 0.064 13.2 0.0 0.21 11.6 0.0 1.9 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain PaaX PF07848.12 EMT52603.1 - 0.084 13.1 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 PaaX-like protein TetR_C_28 PF17937.1 EMT52603.1 - 0.097 13.1 2.3 0.16 12.5 0.8 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 EMT52604.1 - 6.4e-51 173.3 53.5 6.4e-39 133.9 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT52604.1 - 3.2e-33 115.3 31.7 1.5e-19 70.2 15.5 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EMT52604.1 - 6e-07 28.4 26.6 3.1e-06 26.0 24.8 2.4 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 EMT52604.1 - 0.0027 16.6 11.2 0.0027 16.6 11.2 3.6 2 2 0 3 3 3 2 MFS_1 like family MFS_4 PF06779.14 EMT52604.1 - 0.0056 16.0 30.6 0.019 14.2 30.7 1.7 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PTE PF02126.18 EMT52605.1 - 0.0026 17.2 0.0 0.0053 16.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotriesterase family Amidohydro_1 PF01979.20 EMT52605.1 - 0.03 13.6 0.0 0.87 8.8 0.0 2.4 2 1 0 2 2 2 0 Amidohydrolase family Lactamase_B PF00753.27 EMT52606.1 - 2e-19 70.4 0.2 2.7e-19 70.0 0.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EMT52606.1 - 0.0055 16.6 0.0 0.038 13.9 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EMT52606.1 - 0.012 15.2 0.1 0.019 14.5 0.1 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF5519 PF17648.1 EMT52606.1 - 0.078 12.8 0.9 0.26 11.2 0.0 2.2 2 1 1 3 3 3 0 Family of unknown function (DUF5519) DAO PF01266.24 EMT52607.1 - 1.3e-68 232.2 0.0 1.6e-68 231.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMT52607.1 - 4.2e-07 29.5 1.0 0.0016 17.7 0.2 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT52607.1 - 2.1e-06 27.2 0.6 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EMT52607.1 - 4.7e-06 25.4 0.1 0.09 11.3 0.0 2.5 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 EMT52607.1 - 0.0001 22.8 1.3 0.69 10.5 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMT52607.1 - 0.00034 20.0 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EMT52607.1 - 0.00051 19.4 0.5 0.0051 16.1 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EMT52607.1 - 0.00074 18.8 0.8 0.002 17.4 0.1 2.1 4 0 0 4 4 4 1 Thi4 family NAD_binding_8 PF13450.6 EMT52607.1 - 0.00077 19.6 0.2 0.0018 18.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMT52607.1 - 0.0073 15.4 0.1 0.086 11.9 0.1 2.3 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EMT52607.1 - 0.02 14.0 0.0 4.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 EMT52607.1 - 0.034 12.9 0.4 3 6.4 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 EMT52607.1 - 0.23 11.5 1.9 0.56 10.2 0.1 2.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EMT52607.1 - 0.26 10.1 0.3 1.6 7.5 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase EAL PF00563.20 EMT52608.1 - 1.1e-76 257.5 0.0 1.6e-76 257.0 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 EMT52608.1 - 5.8e-49 165.9 0.0 9.2e-49 165.3 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MHYT PF03707.16 EMT52608.1 - 5.6e-45 151.3 22.6 1.7e-16 60.1 0.9 4.4 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat PAS_9 PF13426.7 EMT52608.1 - 4e-08 33.5 0.1 1.5e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EMT52608.1 - 0.00021 21.5 0.0 0.00049 20.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EMT52608.1 - 0.00098 19.1 0.0 0.0025 17.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold LysR_substrate PF03466.20 EMT52609.1 - 7.1e-53 179.1 0.0 9.7e-53 178.6 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT52609.1 - 2e-22 78.9 0.0 3.6e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR PF01047.22 EMT52609.1 - 0.017 15.1 0.1 0.13 12.2 0.0 2.4 3 0 0 3 3 3 0 MarR family HTH_50 PF18024.1 EMT52609.1 - 0.036 13.7 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 EMT52609.1 - 0.082 13.1 0.1 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 EMT52609.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding LrgA PF03788.14 EMT52610.1 - 6.2e-26 90.2 9.2 6.2e-26 90.2 9.2 1.3 1 1 0 1 1 1 1 LrgA family DUF5489 PF17592.2 EMT52610.1 - 0.27 11.8 5.9 1.2 9.7 1.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5489) LrgB PF04172.16 EMT52611.1 - 1.3e-76 256.9 13.5 1.5e-76 256.7 13.5 1.0 1 0 0 1 1 1 1 LrgB-like family LrgA PF03788.14 EMT52611.1 - 0.0034 17.3 0.7 0.0034 17.3 0.7 3.0 3 1 0 3 3 3 1 LrgA family HATPase_c PF02518.26 EMT52612.1 - 3.4e-41 140.3 1.2 1.9e-26 92.8 0.1 2.3 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMT52612.1 - 4.4e-27 94.5 0.0 8.8e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain His_kinase PF06580.13 EMT52612.1 - 4.7e-20 71.7 1.3 4.7e-20 71.7 1.3 2.1 2 0 0 2 2 2 1 Histidine kinase HisKA PF00512.25 EMT52612.1 - 1.2e-11 44.4 2.1 3.1e-11 43.2 2.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EMT52612.1 - 2.3e-07 30.7 0.0 0.0069 16.2 0.0 2.3 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT52612.1 - 9.9e-07 28.8 0.1 0.048 13.6 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain 7TMR-DISM_7TM PF07695.11 EMT52612.1 - 6.4e-05 23.0 37.3 6.4e-05 23.0 37.3 1.6 2 0 0 2 2 2 1 7TM diverse intracellular signalling HATPase_c_5 PF14501.6 EMT52612.1 - 0.0013 18.6 0.0 0.024 14.5 0.0 2.4 2 0 0 2 2 2 1 GHKL domain MFS_1 PF07690.16 EMT52613.1 - 1.2e-49 169.2 43.0 4.6e-49 167.2 32.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT52613.1 - 2.9e-05 23.1 1.5 0.00044 19.2 0.1 3.0 1 1 0 2 2 2 1 MFS_1 like family OATP PF03137.20 EMT52613.1 - 0.0053 15.1 0.0 0.0053 15.1 0.0 2.8 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family NCE101 PF11654.8 EMT52613.1 - 0.1 12.3 0.3 0.1 12.3 0.3 2.7 2 0 0 2 2 2 0 Non-classical export protein 1 Pyr_redox_3 PF13738.6 EMT52614.1 - 2.3e-23 82.9 2.7 3.1e-21 75.9 0.6 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMT52614.1 - 2.5e-22 79.5 0.1 3.3e-22 79.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT52614.1 - 3.3e-09 35.9 0.1 0.00011 21.1 0.0 3.2 3 1 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 EMT52614.1 - 4e-08 33.7 0.8 6.3e-05 23.5 0.0 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMT52614.1 - 0.0002 20.6 0.7 0.0012 18.1 0.2 2.2 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EMT52614.1 - 0.00041 18.9 0.0 0.00068 18.2 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EMT52614.1 - 0.00078 19.6 0.0 0.0023 18.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMT52614.1 - 0.00097 18.6 0.0 0.0052 16.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EMT52614.1 - 0.00098 18.3 0.9 0.79 8.7 0.0 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EMT52614.1 - 0.0047 16.1 0.1 0.78 8.7 0.0 3.1 3 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 EMT52614.1 - 0.0069 15.7 0.0 0.086 12.1 0.0 2.4 2 0 0 2 2 2 1 Thi4 family TaqI_C PF12950.7 EMT52614.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain NAD_binding_9 PF13454.6 EMT52614.1 - 0.047 13.7 0.3 2.2 8.2 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 EMT52614.1 - 0.1 12.2 0.8 6.8 6.2 0.1 2.6 1 1 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EMT52614.1 - 0.11 11.8 0.1 2.8 7.1 0.0 2.4 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase ABC_tran PF00005.27 EMT52615.1 - 7.8e-32 110.7 0.0 1.1e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT52615.1 - 5.7e-10 39.0 0.0 0.00012 21.6 0.1 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT52615.1 - 2.4e-08 34.1 2.9 4.1e-07 30.0 0.3 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EMT52615.1 - 4.5e-08 33.3 0.9 3e-05 24.0 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMT52615.1 - 2.9e-06 27.9 1.1 4.1e-06 27.4 1.1 1.5 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EMT52615.1 - 2.9e-05 23.0 0.5 0.0033 16.3 0.1 2.2 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 EMT52615.1 - 3.7e-05 23.4 0.1 8.9e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT52615.1 - 0.00025 21.4 0.6 0.0014 19.0 0.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EMT52615.1 - 0.0017 18.1 0.4 0.0033 17.2 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMT52615.1 - 0.0027 17.7 0.2 2.1 8.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EMT52615.1 - 0.0033 16.7 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 EMT52615.1 - 0.0038 17.2 0.1 0.007 16.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 EMT52615.1 - 0.0047 16.9 0.2 0.063 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMT52615.1 - 0.0072 16.6 0.6 0.037 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EMT52615.1 - 0.011 15.3 0.2 0.018 14.6 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 EMT52615.1 - 0.015 15.3 0.8 0.059 13.3 0.1 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_27 PF13514.6 EMT52615.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 EMT52615.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA PF00004.29 EMT52615.1 - 0.021 15.3 0.9 0.13 12.7 0.9 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EMT52615.1 - 0.021 14.9 0.4 0.2 11.7 0.1 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase MukB PF04310.12 EMT52615.1 - 0.024 14.4 0.3 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 MukB N-terminal NB-ARC PF00931.22 EMT52615.1 - 0.027 13.7 0.1 0.057 12.6 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 EMT52615.1 - 0.031 13.7 0.2 0.22 10.9 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EMT52615.1 - 0.042 13.8 0.2 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 EMT52615.1 - 0.043 13.0 0.3 0.077 12.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 EMT52615.1 - 0.051 13.5 0.8 0.09 12.7 0.2 1.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EMT52615.1 - 0.06 13.6 0.7 0.14 12.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMT52615.1 - 0.061 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 EMT52615.1 - 0.063 13.0 0.2 0.17 11.6 0.1 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.7 EMT52615.1 - 0.067 12.1 0.1 1.8 7.4 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain TrwB_AAD_bind PF10412.9 EMT52615.1 - 0.088 11.7 0.5 0.17 10.8 0.1 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 EMT52615.1 - 0.091 12.9 0.3 0.48 10.6 0.3 2.0 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 EMT52615.1 - 0.12 12.0 0.1 0.17 11.6 0.1 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.20 EMT52615.1 - 0.23 10.6 0.2 0.66 9.1 0.1 1.7 2 0 0 2 2 2 0 G-protein alpha subunit AAA_19 PF13245.6 EMT52615.1 - 1 9.7 3.4 4.2 7.7 3.4 1.9 1 1 0 1 1 1 0 AAA domain Peripla_BP_2 PF01497.18 EMT52616.1 - 1.3e-30 106.8 0.5 1.7e-30 106.3 0.5 1.1 1 0 0 1 1 1 1 Periplasmic binding protein LPAM_1 PF08139.12 EMT52616.1 - 2.6 8.7 3.9 7.9 7.2 3.9 1.8 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site FecCD PF01032.18 EMT52617.1 - 4e-84 282.3 39.4 4.6e-84 282.1 39.4 1.0 1 0 0 1 1 1 1 FecCD transport family DUF2631 PF10939.8 EMT52617.1 - 5.7 6.9 8.1 1.1 9.1 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) FecCD PF01032.18 EMT52618.1 - 1.6e-86 290.1 30.1 2e-86 289.8 30.1 1.0 1 0 0 1 1 1 1 FecCD transport family B12D PF06522.11 EMT52618.1 - 8.6 6.2 5.8 9.3 6.1 0.5 3.5 2 1 1 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit NAD_binding_10 PF13460.6 EMT52619.1 - 1.4e-42 145.7 0.5 1.6e-42 145.5 0.5 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMT52619.1 - 5.7e-14 52.2 0.1 1.5e-13 50.8 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EMT52619.1 - 5.3e-08 32.2 0.0 6.7e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMT52619.1 - 6.7e-08 32.3 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EMT52619.1 - 8.2e-06 26.0 0.7 1.5e-05 25.1 0.6 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 EMT52619.1 - 6.5e-05 23.1 0.5 0.00014 22.0 0.5 1.6 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EMT52619.1 - 0.0068 15.6 0.0 0.92 8.6 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 EMT52619.1 - 0.016 14.7 0.2 0.06 12.8 0.2 2.1 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 EMT52619.1 - 0.021 13.9 0.1 0.031 13.4 0.1 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain HIM1 PF08732.10 EMT52619.1 - 0.031 13.8 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 HIM1 KR PF08659.10 EMT52619.1 - 0.06 13.3 0.0 3.2 7.6 0.1 2.3 2 0 0 2 2 2 0 KR domain TrkA_N PF02254.18 EMT52619.1 - 0.075 13.3 0.7 0.15 12.3 0.1 1.9 2 1 0 2 2 2 0 TrkA-N domain Semialdhyde_dh PF01118.24 EMT52619.1 - 0.091 13.2 0.2 0.15 12.5 0.2 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EMT52619.1 - 0.1 12.0 0.1 0.28 10.5 0.1 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF4179 PF13786.6 EMT52620.1 - 1.8e-17 63.6 0.9 1.5e-16 60.6 0.3 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4179) zf-HC2 PF13490.6 EMT52620.1 - 9.8e-10 38.5 4.6 2e-09 37.5 4.6 1.6 1 0 0 1 1 1 1 Putative zinc-finger DUF5643 PF18705.1 EMT52620.1 - 1.2e-07 31.7 3.7 0.094 12.7 0.0 4.0 3 1 0 3 3 3 3 Family of unknown function (DUF5643) Pyr_redox PF00070.27 EMT52620.1 - 0.058 14.0 0.0 2.1 9.0 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GHL6 PF14871.6 EMT52620.1 - 0.064 13.4 0.1 9.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 ARHGEF5_35 PF15441.6 EMT52620.1 - 0.081 11.9 0.2 0.12 11.3 0.2 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 Sigma70_r2 PF04542.14 EMT52621.1 - 1.3e-16 60.1 0.2 2.1e-16 59.4 0.2 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT52621.1 - 1.6e-16 59.7 0.4 2.6e-16 59.0 0.4 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT52621.1 - 4.3e-11 42.1 0.1 8.1e-11 41.3 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT52621.1 - 2e-05 24.6 0.6 2.7e-05 24.1 0.6 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 EMT52621.1 - 0.0045 16.7 0.0 0.016 15.0 0.0 1.9 1 1 1 2 2 2 1 Homeodomain-like domain GerE PF00196.19 EMT52621.1 - 0.022 14.3 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_WhiA PF02650.14 EMT52621.1 - 0.022 15.1 0.3 0.08 13.3 0.1 2.0 2 0 0 2 2 2 0 WhiA C-terminal HTH domain HTH_16 PF12645.7 EMT52621.1 - 0.065 13.3 3.0 0.094 12.8 0.2 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_10 PF04967.12 EMT52621.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain GED PF02212.18 EMT52621.1 - 0.16 12.1 2.0 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 Dynamin GTPase effector domain DUF4367 PF14285.6 EMT52622.1 - 4.7e-14 52.7 0.0 7.6e-06 26.3 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4367) UPF0128 PF03673.13 EMT52622.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) ABC_tran PF00005.27 EMT52623.1 - 9.8e-37 126.5 0.0 1.4e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT52623.1 - 4.6e-15 56.2 0.0 3.2e-09 37.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT52623.1 - 8.3e-09 35.2 1.6 2e-08 33.9 1.6 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMT52623.1 - 5.1e-06 27.1 0.3 1.1e-05 26.1 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.6 EMT52623.1 - 9.9e-06 24.5 0.0 0.023 13.4 0.0 2.0 1 1 1 2 2 2 2 AAA domain ABC_ATPase PF09818.9 EMT52623.1 - 2.6e-05 23.2 0.7 0.13 11.0 0.1 2.9 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 EMT52623.1 - 6.2e-05 22.9 0.4 0.00091 19.0 0.3 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EMT52623.1 - 8.4e-05 22.2 0.1 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMT52623.1 - 0.00052 20.0 0.2 0.0011 19.0 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 EMT52623.1 - 0.0043 17.3 0.0 0.08 13.2 0.0 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 EMT52623.1 - 0.0046 16.2 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.6 EMT52623.1 - 0.005 17.2 0.1 0.0091 16.4 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT52623.1 - 0.006 16.9 0.5 0.03 14.6 0.5 2.1 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EMT52623.1 - 0.039 13.1 0.1 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 EMT52623.1 - 0.062 13.5 0.2 0.11 12.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EMT52623.1 - 0.073 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EMT52623.1 - 0.095 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMT52623.1 - 0.15 11.6 0.1 0.86 9.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 EMT52624.1 - 2.7e-20 72.9 9.1 2.7e-20 72.9 9.1 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Gly-zipper_YMGG PF13441.6 EMT52624.1 - 0.048 13.4 0.5 0.1 12.4 0.5 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF445 PF04286.12 EMT52624.1 - 1.5 8.5 5.5 2.2 8.0 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) FtsX PF02687.21 EMT52624.1 - 3 8.4 9.6 13 6.3 0.0 3.0 2 1 0 3 3 3 0 FtsX-like permease family SBP_bac_3 PF00497.20 EMT52625.1 - 2.5e-40 138.3 2.6 6e-40 137.1 2.6 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EMT52625.1 - 1.8e-10 41.0 0.1 4.3e-09 36.6 0.0 2.8 2 1 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site LPAM_1 PF08139.12 EMT52625.1 - 0.12 12.9 0.8 0.28 11.7 0.8 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site LPAM_2 PF13627.6 EMT52625.1 - 0.94 9.4 4.0 1.6 8.7 4.0 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF4367 PF14285.6 EMT52626.1 - 0.0092 16.4 1.8 0.04 14.3 1.8 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4367) DUF4245 PF14030.6 EMT52626.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4245) DUF418 PF04235.12 EMT52627.1 - 1.5e-41 142.1 5.4 1.5e-41 142.1 5.4 2.4 3 1 0 3 3 3 1 Protein of unknown function (DUF418) Tom6 PF17112.5 EMT52627.1 - 0.13 11.8 0.4 0.41 10.2 0.4 1.8 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal HisKA_3 PF07730.13 EMT52628.1 - 7e-22 77.7 1.5 1.1e-21 77.0 0.5 1.9 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 EMT52628.1 - 8e-06 26.3 0.1 0.00037 21.0 0.1 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT52628.1 - 0.0005 20.0 0.0 0.0013 18.7 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HisKA PF00512.25 EMT52628.1 - 0.087 12.9 0.2 0.2 11.7 0.2 1.7 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain MadL PF03817.13 EMT52628.1 - 0.21 11.7 2.0 0.55 10.3 1.9 1.8 1 1 0 1 1 1 0 Malonate transporter MadL subunit DUF2070 PF09843.9 EMT52628.1 - 2.4 6.3 8.7 4.5 5.4 8.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Response_reg PF00072.24 EMT52629.1 - 1e-25 90.1 0.3 1.7e-25 89.4 0.1 1.5 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 EMT52629.1 - 1.8e-15 56.2 0.5 7.2e-15 54.3 0.2 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family DUF3489 PF11994.8 EMT52629.1 - 4.6e-05 23.4 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3489) HTH_40 PF14493.6 EMT52629.1 - 0.0011 19.4 1.1 0.0034 17.8 0.2 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 EMT52629.1 - 0.0029 17.1 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EMT52629.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 EMT52629.1 - 0.039 13.7 0.0 0.15 11.9 0.0 1.9 1 1 1 2 2 2 0 Homeodomain-like domain HTH_10 PF04967.12 EMT52629.1 - 0.092 12.6 0.2 0.47 10.3 0.0 2.4 2 0 0 2 2 2 0 HTH DNA binding domain AA_permease PF00324.21 EMT52630.1 - 2.3e-99 333.2 55.1 2.9e-99 332.8 55.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMT52630.1 - 6.4e-41 140.6 58.4 8.6e-41 140.2 58.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF188 PF02639.14 EMT52631.1 - 0.021 14.5 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 HATPase_c PF02518.26 EMT52632.1 - 0.017 15.6 0.1 0.018 15.5 0.1 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMT52632.1 - 0.15 11.9 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3-dmu-9_3-mt PF06983.13 EMT52633.1 - 8.9e-10 39.1 1.4 1.2e-09 38.7 1.4 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase META PF03724.16 EMT52633.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 META domain MarR PF01047.22 EMT52634.1 - 6.2e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 EMT52634.1 - 0.005 16.7 0.0 0.012 15.5 0.0 1.6 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 EMT52634.1 - 0.0055 16.6 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EMT52634.1 - 0.0095 16.4 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 EMT52634.1 - 0.03 14.1 0.0 0.078 12.8 0.0 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF2250 PF10007.9 EMT52634.1 - 0.044 13.9 0.0 1.2 9.3 0.0 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) COesterase PF00135.28 EMT52634.1 - 0.14 11.0 0.4 0.21 10.4 0.1 1.4 2 0 0 2 2 2 0 Carboxylesterase family Nitroreductase PF00881.24 EMT52635.1 - 4.6e-21 75.6 0.8 4e-20 72.6 0.8 2.0 1 1 0 1 1 1 1 Nitroreductase family GvpK PF05121.12 EMT52635.1 - 0.012 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Gas vesicle protein K TM1586_NiRdase PF14512.6 EMT52635.1 - 0.015 14.9 0.0 0.68 9.5 0.1 2.2 2 0 0 2 2 2 0 Putative TM nitroreductase SpoOE-like PF09388.10 EMT52638.1 - 3.1e-12 46.2 0.2 4.3e-12 45.7 0.2 1.2 1 0 0 1 1 1 1 Spo0E like sporulation regulatory protein NYD-SP28 PF14772.6 EMT52638.1 - 0.11 12.6 0.1 0.15 12.1 0.1 1.1 1 0 0 1 1 1 0 Sperm tail HTH_3 PF01381.22 EMT52639.1 - 3e-08 33.6 1.2 9.6e-07 28.8 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix TPR_2 PF07719.17 EMT52639.1 - 8.3e-07 28.7 1.9 0.94 9.8 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMT52639.1 - 9.5e-05 22.3 7.3 0.058 13.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat HTH_19 PF12844.7 EMT52639.1 - 0.00011 22.2 1.8 0.0022 18.0 0.1 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 EMT52639.1 - 0.00042 20.6 0.0 0.0017 18.6 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain TPR_1 PF00515.28 EMT52639.1 - 0.00086 19.0 2.3 12 5.9 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMT52639.1 - 0.0033 18.1 0.3 21 6.3 0.0 4.8 5 1 1 6 6 5 0 Tetratricopeptide repeat HTH_26 PF13443.6 EMT52639.1 - 0.0034 17.8 0.0 0.026 14.9 0.0 2.3 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain TPR_12 PF13424.6 EMT52639.1 - 0.0066 16.7 0.7 1.2 9.4 0.1 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat HTH_25 PF13413.6 EMT52639.1 - 0.0092 15.8 0.1 0.049 13.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Cas9-BH PF16593.5 EMT52639.1 - 0.34 10.7 1.3 17 5.2 0.0 2.9 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 HTH_26 PF13443.6 EMT52640.1 - 6.1e-10 39.4 0.2 6.8e-10 39.2 0.2 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 EMT52640.1 - 7e-06 26.0 0.1 9.7e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EMT52640.1 - 0.00022 21.2 0.4 0.00025 21.0 0.4 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 EMT52640.1 - 0.0016 18.4 0.5 0.0022 17.9 0.4 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_35 PF13693.6 EMT52640.1 - 0.0071 16.4 0.0 0.0084 16.1 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF3744 PF12558.8 EMT52640.1 - 0.1 13.4 0.1 0.14 13.0 0.1 1.3 1 1 0 1 1 1 0 ATP-binding cassette cobalt transporter MazG-like PF12643.7 EMT52642.1 - 6e-22 77.7 2.1 7.4e-22 77.4 2.1 1.1 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 EMT52642.1 - 1.8e-06 28.1 0.4 2.5e-06 27.5 0.4 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain dUTPase_2 PF08761.11 EMT52642.1 - 0.00045 20.4 1.1 0.00045 20.4 1.1 1.1 1 0 0 1 1 1 1 dUTPase Vhr1 PF04001.13 EMT52642.1 - 0.045 14.1 0.8 0.077 13.3 0.8 1.6 1 1 0 1 1 1 0 Transcription factor Vhr1 DUF4830 PF16112.5 EMT52642.1 - 0.091 13.2 0.1 0.16 12.5 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4830) DUF2075 PF09848.9 EMT52643.1 - 2.9e-97 326.2 0.3 4.5e-97 325.5 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EMT52643.1 - 1.2e-05 25.6 0.2 0.00019 21.7 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMT52643.1 - 4.8e-05 23.2 0.0 8.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EMT52643.1 - 0.00015 21.8 1.1 0.0018 18.3 0.1 2.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit NERD PF08378.11 EMT52643.1 - 0.0021 18.5 0.1 0.012 16.1 0.1 2.3 2 0 0 2 2 2 1 Nuclease-related domain AAA_19 PF13245.6 EMT52643.1 - 0.011 16.0 0.1 0.035 14.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMT52643.1 - 0.024 14.8 0.1 0.25 11.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 EMT52643.1 - 0.027 13.8 0.0 0.063 12.6 0.0 1.6 1 0 0 1 1 1 0 KaiC Viral_helicase1 PF01443.18 EMT52643.1 - 0.033 13.9 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 EMT52643.1 - 0.04 14.4 0.2 0.3 11.5 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EMT52643.1 - 0.055 13.2 0.1 4.4 7.0 0.0 2.5 1 1 1 2 2 2 0 AAA domain TIR_2 PF13676.6 EMT52644.1 - 3.2e-09 37.4 0.0 1.3e-08 35.5 0.0 2.0 3 0 0 3 3 3 1 TIR domain AAA_16 PF13191.6 EMT52644.1 - 3.7e-05 24.2 2.1 0.077 13.4 0.6 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA PF00004.29 EMT52644.1 - 0.00022 21.7 0.2 0.00059 20.3 0.2 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMT52644.1 - 0.00044 20.0 0.1 0.01 15.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMT52644.1 - 0.00045 20.5 2.1 0.48 10.7 0.1 3.0 2 1 1 3 3 3 2 AAA domain TniB PF05621.11 EMT52644.1 - 0.046 13.1 0.6 0.35 10.3 0.1 2.1 1 1 0 2 2 2 0 Bacterial TniB protein RdDM_RDM1 PF09187.10 EMT52644.1 - 0.1 12.7 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 RNA-directed DNA methylation 1 LAM_C PF12544.8 EMT52645.1 - 0.08 13.1 1.0 0.15 12.2 1.0 1.4 1 0 0 1 1 1 0 Lysine-2,3-aminomutase DM PF00751.18 EMT52645.1 - 0.39 10.7 2.2 0.52 10.3 0.3 2.1 2 0 0 2 2 2 0 DM DNA binding domain Strep_his_triad PF04270.13 EMT52646.1 - 0.17 11.9 0.0 0.62 10.1 0.0 2.0 1 0 0 1 1 1 0 Streptococcal histidine triad protein SPOUT_MTase PF02590.17 EMT52648.1 - 4.2e-61 205.4 0.2 4.7e-61 205.3 0.2 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase Cas_VVA1548 PF09652.10 EMT52648.1 - 0.093 13.0 0.2 0.28 11.4 0.1 1.7 2 0 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) MadM PF03818.13 EMT52648.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit YyzF PF14116.6 EMT52649.1 - 8.7e-13 48.1 2.7 1.2e-12 47.6 2.7 1.2 1 0 0 1 1 1 1 YyzF-like protein SspH PF08141.12 EMT52650.1 - 9.4e-26 89.7 1.0 1e-25 89.6 1.0 1.0 1 0 0 1 1 1 1 Small acid-soluble spore protein H family DUF4179 PF13786.6 EMT52651.1 - 1.1e-06 29.0 0.2 2.5e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) ATP1G1_PLM_MAT8 PF02038.16 EMT52651.1 - 0.11 12.0 0.7 0.21 11.0 0.7 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family CBX7_C PF17218.3 EMT52651.1 - 1.9 8.3 4.1 5 6.9 4.1 1.6 1 0 0 1 1 1 0 CBX family C-terminal motif DUF4179 PF13786.6 EMT52652.1 - 9.1e-19 67.7 0.1 1.8e-18 66.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) DUF5643 PF18705.1 EMT52652.1 - 2.8e-12 46.6 0.3 3.4e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5643) Lum_binding PF00677.17 EMT52652.1 - 0.063 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Lumazine binding domain Sigma70_r4_2 PF08281.12 EMT52653.1 - 1.2e-14 53.7 0.5 1.2e-14 53.7 0.5 1.9 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT52653.1 - 2.6e-14 52.5 0.2 5.3e-14 51.5 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT52653.1 - 4.5e-10 39.1 1.0 4.5e-10 39.1 1.0 1.7 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 EMT52653.1 - 2.6e-06 27.4 0.3 3.2e-06 27.2 0.3 1.2 1 0 0 1 1 1 1 ECF sigma factor DUF4835 PF16119.5 EMT52653.1 - 0.0019 17.4 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4835) Phage_antitermQ PF06530.12 EMT52653.1 - 0.019 14.9 0.0 0.055 13.4 0.0 1.7 2 0 0 2 2 2 0 Phage antitermination protein Q HTH_WhiA PF02650.14 EMT52653.1 - 0.053 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 WhiA C-terminal HTH domain GerE PF00196.19 EMT52653.1 - 0.079 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF722 PF05263.11 EMT52653.1 - 0.081 13.1 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF722) PLDc_2 PF13091.6 EMT52654.1 - 2.5e-41 140.7 0.0 5.4e-26 91.1 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EMT52654.1 - 1.7e-16 59.6 0.4 3.9e-07 30.0 0.2 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_N PF13396.6 EMT52654.1 - 2.8e-11 43.2 6.4 5.7e-11 42.2 6.4 1.5 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF4260 PF14079.6 EMT52654.1 - 0.094 12.7 1.9 0.17 11.8 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4260) MCPsignal PF00015.21 EMT52655.1 - 2.4e-41 141.4 18.8 2.4e-41 141.4 18.8 4.3 1 1 3 4 4 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 EMT52655.1 - 1.1e-25 90.2 2.7 1.1e-25 90.2 2.7 4.1 2 1 1 3 3 2 2 Four helix bundle sensory module for signal transduction TarH PF02203.15 EMT52655.1 - 0.00016 21.6 0.2 0.00016 21.6 0.2 4.4 3 2 1 5 5 5 1 Tar ligand binding domain homologue DUF948 PF06103.11 EMT52655.1 - 0.03 14.6 38.5 0.16 12.2 1.1 6.4 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF948) AI-2E_transport PF01594.16 EMT52655.1 - 0.067 12.3 16.8 0.012 14.8 6.8 3.1 3 1 0 3 3 3 0 AI-2E family transporter Phage_holin_3_6 PF07332.11 EMT52655.1 - 0.096 12.7 1.5 0.76 9.8 0.1 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1664 PF07889.12 EMT52655.1 - 0.2 11.7 26.2 0.076 13.1 6.7 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) Alanine_zipper PF11839.8 EMT52655.1 - 0.61 10.5 0.0 0.61 10.5 0.0 4.7 6 0 0 6 6 5 0 Alanine-zipper, major outer membrane lipoprotein FliJ PF02050.16 EMT52655.1 - 0.63 10.3 22.5 0.1 12.8 3.3 3.7 4 0 0 4 4 4 0 Flagellar FliJ protein DUF5058 PF16481.5 EMT52655.1 - 0.82 9.3 10.4 0.045 13.4 1.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5058) ISG65-75 PF11727.8 EMT52655.1 - 1.2 8.4 19.2 0.23 10.7 1.6 3.3 3 0 0 3 3 3 0 Invariant surface glycoprotein DASH_Dad2 PF08654.10 EMT52655.1 - 1.7 9.1 28.0 0.28 11.6 1.8 4.6 2 2 1 4 4 4 0 DASH complex subunit Dad2 ATP-synt_ab PF00006.25 EMT52655.1 - 1.9 8.1 11.7 0.091 12.4 3.0 2.6 1 1 1 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2408 PF10303.9 EMT52655.1 - 1.9 9.1 10.6 10 6.7 2.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) NPV_P10 PF05531.12 EMT52655.1 - 5 7.7 28.2 11 6.6 0.5 5.3 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF1043 PF06295.12 EMT52655.1 - 6.3 6.8 10.7 0.71 9.9 1.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Trypsin_2 PF13365.6 EMT52656.1 - 3.4e-29 102.7 0.6 6.5e-29 101.8 0.6 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 EMT52656.1 - 5.2e-16 58.7 0.3 3.9e-15 55.9 0.0 2.5 2 1 0 2 2 2 1 PDZ domain Trypsin PF00089.26 EMT52656.1 - 3.7e-12 46.5 0.1 6e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 EMT52656.1 - 5.4e-06 26.2 0.0 2.2e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EMT52656.1 - 0.0073 16.6 3.8 0.041 14.2 0.1 3.6 4 1 0 4 4 4 1 PDZ domain Peptidase_S32 PF05579.13 EMT52656.1 - 0.018 14.2 0.2 3.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 DUF31 PF01732.16 EMT52656.1 - 0.06 12.9 2.2 2 7.9 0.1 2.7 1 1 1 3 3 3 0 Putative peptidase (DUF31) Cadherin-like PF12733.7 EMT52656.1 - 1.9 9.1 4.3 2.2 8.9 0.0 3.0 3 1 1 4 4 4 0 Cadherin-like beta sandwich domain Lactamase_B_2 PF12706.7 EMT52657.1 - 6.6e-21 74.8 0.0 8.8e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMT52657.1 - 2.9e-20 73.1 0.1 3.5e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EMT52657.1 - 0.00018 21.0 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain YycI PF09648.10 EMT52658.1 - 3.5e-27 95.5 0.0 4.3e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 YycH protein YycH PF07435.11 EMT52659.1 - 4e-58 197.4 0.1 5.1e-58 197.1 0.1 1.1 1 0 0 1 1 1 1 YycH protein YycI PF09648.10 EMT52659.1 - 4.5e-06 26.4 1.2 7.6e-06 25.7 1.2 1.3 1 0 0 1 1 1 1 YycH protein HATPase_c PF02518.26 EMT52660.1 - 1.1e-30 106.4 0.4 3.2e-29 101.7 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT52660.1 - 4.3e-19 68.3 0.2 1.4e-18 66.7 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EMT52660.1 - 2.7e-17 62.9 0.8 6.2e-17 61.7 0.1 2.1 2 0 0 2 2 1 1 HAMP domain PAS_4 PF08448.10 EMT52660.1 - 3.3e-08 33.8 0.0 1.5e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EMT52660.1 - 5.3e-08 33.1 0.0 1.7e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EMT52660.1 - 3.9e-06 26.8 0.2 2.1e-05 24.5 0.2 2.2 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EMT52660.1 - 1.2e-05 25.2 0.0 3.3e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 EMT52660.1 - 0.0001 22.5 1.8 0.0023 18.0 0.6 3.3 3 1 0 3 3 3 1 PAS fold dCache_1 PF02743.18 EMT52660.1 - 0.0002 21.3 0.4 0.016 15.0 0.3 2.4 2 0 0 2 2 2 1 Cache domain HATPase_c_3 PF13589.6 EMT52660.1 - 0.00026 20.8 0.0 0.00055 19.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EMT52660.1 - 0.006 16.5 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 GHKL domain sCache_3_2 PF17203.4 EMT52660.1 - 0.014 15.5 0.2 0.04 14.1 0.2 1.7 1 0 0 1 1 1 0 Single cache domain 3 YscJ_FliF PF01514.17 EMT52660.1 - 0.016 14.9 0.2 0.37 10.4 0.1 2.5 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family dCache_3 PF14827.6 EMT52660.1 - 0.017 14.8 1.0 0.17 11.5 0.1 2.6 3 0 0 3 3 3 0 Double sensory domain of two-component sensor kinase Diacid_rec PF05651.13 EMT52660.1 - 0.074 12.7 0.1 0.28 10.8 0.1 2.1 1 0 0 1 1 1 0 Putative sugar diacid recognition FxsA PF04186.13 EMT52660.1 - 0.1 12.7 2.1 7.8 6.7 0.2 2.6 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein Response_reg PF00072.24 EMT52661.1 - 1.5e-30 105.7 0.1 3.2e-30 104.6 0.1 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT52661.1 - 9.6e-29 99.3 0.2 1.9e-28 98.3 0.2 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Peptidase_M23 PF01551.22 EMT52662.1 - 1.6e-29 102.0 2.0 1.6e-29 102.0 2.0 3.2 3 1 0 3 3 3 1 Peptidase family M23 G5 PF07501.12 EMT52662.1 - 4.5e-21 75.1 13.2 4.9e-21 74.9 10.8 2.4 2 0 0 2 2 2 1 G5 domain LysM PF01476.20 EMT52662.1 - 1.9e-07 31.0 0.1 5.3e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 LysM domain DUF883 PF05957.13 EMT52662.1 - 0.38 11.4 2.9 0.5 11.0 0.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) SPOR PF05036.13 EMT52663.1 - 0.018 15.4 0.1 0.078 13.4 0.0 1.9 2 0 0 2 2 2 0 Sporulation related domain LSM PF01423.22 EMT52664.1 - 0.0052 16.5 0.2 0.006 16.2 0.2 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EMT52664.1 - 0.017 15.2 0.3 0.021 15.0 0.3 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Adenylsucc_synt PF00709.21 EMT52665.1 - 4e-185 615.7 0.1 4.6e-185 615.5 0.1 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DnaB_C PF03796.15 EMT52666.1 - 3.6e-118 393.5 0.1 6.2e-118 392.7 0.1 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 EMT52666.1 - 2.5e-38 130.3 0.1 6.2e-38 129.0 0.1 1.7 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 EMT52666.1 - 3.1e-14 53.0 0.0 6.2e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EMT52666.1 - 7.7e-06 25.4 0.0 8.8e-05 22.0 0.0 2.0 1 1 0 2 2 2 1 KaiC AAA PF00004.29 EMT52666.1 - 3.4e-05 24.3 0.0 9.2e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EMT52666.1 - 0.34 10.6 1.8 1.7 8.3 1.8 2.0 1 1 0 1 1 1 0 AAA domain Ribosomal_L9_C PF03948.14 EMT52667.1 - 1.4e-26 92.7 4.9 2.3e-26 92.1 4.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 EMT52667.1 - 9.2e-21 73.1 0.5 2.2e-20 71.9 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Put_DNA-bind_N PF06971.13 EMT52667.1 - 0.23 11.5 2.0 2.6 8.1 0.2 2.7 3 0 0 3 3 3 0 Putative DNA-binding protein N-terminus DHH PF01368.20 EMT52668.1 - 2.9e-21 75.6 0.1 5.4e-21 74.7 0.1 1.5 1 0 0 1 1 1 1 DHH family DHHA1 PF02272.19 EMT52668.1 - 2.5e-15 57.1 0.7 2.5e-15 57.1 0.7 2.0 2 0 0 2 2 2 1 DHHA1 domain PAS_8 PF13188.7 EMT52668.1 - 0.0021 18.1 0.0 0.0064 16.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 EMT52668.1 - 0.074 13.3 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 PAS domain CFTR_R PF14396.6 EMT52668.1 - 0.12 11.9 0.2 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain DUF4131 PF13567.6 EMT52668.1 - 0.13 11.9 1.0 0.26 10.9 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2232 PF09991.9 EMT52669.1 - 1e-45 156.1 36.9 2.6e-45 154.8 36.9 1.5 1 1 0 1 1 1 1 Predicted membrane protein (DUF2232) SPW PF03779.14 EMT52669.1 - 2.6 7.7 16.4 0.12 11.9 4.0 3.9 2 1 1 3 3 3 0 SPW repeat Ribosomal_S18 PF01084.20 EMT52670.1 - 1e-27 96.1 1.0 1.3e-27 95.8 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S18 SSB PF00436.25 EMT52671.1 - 1e-38 131.5 0.2 1.2e-38 131.3 0.2 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Ribosomal_S6 PF01250.17 EMT52672.1 - 2.9e-32 110.8 0.6 3.2e-32 110.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 Pox_int_trans PF05718.12 EMT52672.1 - 0.065 11.9 0.1 0.067 11.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus intermediate transcription factor YchF-GTPase_C PF06071.13 EMT52673.1 - 2.6e-42 142.9 0.1 4.7e-42 142.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EMT52673.1 - 1.8e-24 86.0 0.1 4.9e-24 84.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMT52673.1 - 2.8e-08 33.4 0.1 7.6e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Acetyltransf_3 PF13302.7 EMT52674.1 - 6.7e-33 114.3 0.0 7.9e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT52674.1 - 9.9e-09 35.5 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EMT52674.1 - 0.0075 16.4 0.0 0.0084 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMT52674.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M3 PF01432.20 EMT52675.1 - 6e-72 243.4 11.7 9.6e-72 242.7 11.7 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 EMT52675.1 - 6.3e-18 64.8 0.0 3.1e-17 62.6 0.0 2.3 1 0 0 1 1 1 1 Oligopeptidase F Snapin_Pallidin PF14712.6 EMT52675.1 - 0.0019 18.6 0.9 0.0058 17.0 0.1 2.3 2 0 0 2 2 2 1 Snapin/Pallidin TetR_C_5 PF08360.11 EMT52675.1 - 2.2 8.4 8.6 8.2 6.6 0.0 4.1 5 0 0 5 5 5 0 QacR-like protein, C-terminal region DUF951 PF06107.11 EMT52676.1 - 2.4e-30 104.2 2.8 2.8e-30 104.0 2.8 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF951) MS_channel PF00924.18 EMT52677.1 - 6.9e-44 149.9 1.9 6.9e-44 149.9 1.9 1.5 2 0 0 2 2 2 1 Mechanosensitive ion channel TIP49 PF06068.13 EMT52677.1 - 0.01 15.1 0.1 0.015 14.5 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain V-ATPase_C PF03223.15 EMT52677.1 - 0.028 13.8 0.2 3.6 6.9 0.0 2.5 3 0 0 3 3 3 0 V-ATPase subunit C DUF5132 PF17195.4 EMT52677.1 - 0.047 13.8 1.0 0.23 11.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) NnrS PF05940.12 EMT52677.1 - 0.05 13.0 1.6 0.069 12.5 1.6 1.1 1 0 0 1 1 1 0 NnrS protein DUF3343 PF11823.8 EMT52678.1 - 4e-18 64.6 0.0 4.8e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3343) DUF1256 PF06866.11 EMT52679.1 - 3.8e-63 211.8 0.0 4.3e-63 211.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1256) Peptidase_A25 PF03418.14 EMT52679.1 - 0.00019 20.5 0.1 0.022 13.7 0.1 2.8 2 1 0 2 2 2 1 Germination protease DAGK_cat PF00781.24 EMT52680.1 - 7.8e-28 96.6 0.0 1.2e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EMT52680.1 - 6.4e-05 22.3 0.0 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_acc PF00609.19 EMT52680.1 - 0.00028 21.2 0.0 0.0019 18.6 0.0 2.1 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain PFK PF00365.20 EMT52680.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphofructokinase DUF554 PF04474.12 EMT52681.1 - 3.4e-76 255.5 27.7 4.3e-76 255.2 27.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF554) Aminotran_5 PF00266.19 EMT52682.1 - 4.5e-91 305.6 0.0 5.1e-91 305.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EMT52682.1 - 2e-10 39.8 0.0 3.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EMT52682.1 - 1.3e-06 27.8 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMT52682.1 - 0.036 13.4 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ParBc PF02195.18 EMT52683.1 - 1.5e-28 98.9 0.3 3.6e-28 97.7 0.3 1.7 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_ParB PF17762.1 EMT52683.1 - 1.4e-19 69.6 5.1 1.4e-19 69.6 5.1 3.1 4 0 0 4 4 4 1 HTH domain found in ParB protein TrmB PF01978.19 EMT52683.1 - 0.00038 20.3 0.4 0.0014 18.5 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB KorB PF08535.10 EMT52683.1 - 0.00063 19.7 1.3 0.019 15.0 0.0 3.0 3 0 0 3 3 3 1 KorB domain HTH_3 PF01381.22 EMT52683.1 - 0.00065 19.7 2.7 0.0043 17.1 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix HTH_37 PF13744.6 EMT52683.1 - 0.0081 16.1 5.2 0.12 12.4 0.1 3.2 2 1 1 3 3 3 1 Helix-turn-helix domain DUF1016_N PF17761.1 EMT52683.1 - 0.032 14.4 0.0 0.22 11.7 0.0 2.2 2 1 1 3 3 3 0 DUF1016 N-terminal domain UPF0175 PF03683.13 EMT52683.1 - 0.033 13.9 0.5 0.14 11.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) HTH_Crp_2 PF13545.6 EMT52683.1 - 0.035 14.1 0.2 0.23 11.5 0.0 2.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain BACK PF07707.15 EMT52683.1 - 0.064 13.4 2.5 0.14 12.2 0.5 2.6 2 1 0 3 3 3 0 BTB And C-terminal Kelch HTH_26 PF13443.6 EMT52683.1 - 0.37 11.2 1.9 8.9 6.8 0.0 3.2 2 1 1 3 3 3 0 Cro/C1-type HTH DNA-binding domain AAA_31 PF13614.6 EMT52684.1 - 5.4e-72 241.4 2.1 7.3e-72 241.0 1.2 1.6 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EMT52684.1 - 4.4e-28 97.9 0.2 5.8e-28 97.5 0.2 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EMT52684.1 - 6.6e-14 51.9 1.1 1.8e-13 50.5 1.1 1.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EMT52684.1 - 5.6e-13 49.0 0.8 7.3e-08 32.2 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EMT52684.1 - 1.6e-12 47.3 1.0 1.8e-06 27.5 0.5 2.2 2 0 0 2 2 2 2 ATPase MipZ CBP_BcsQ PF06564.12 EMT52684.1 - 5e-10 39.3 0.0 1.6e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 EMT52684.1 - 1.9e-08 33.8 5.2 1.4e-06 27.7 5.2 2.9 1 1 0 1 1 1 1 Anion-transporting ATPase SRP54 PF00448.22 EMT52684.1 - 3.3e-05 23.6 1.4 0.086 12.5 0.2 2.6 2 1 0 2 2 2 2 SRP54-type protein, GTPase domain VirC1 PF07015.11 EMT52684.1 - 0.00048 19.5 1.8 0.0014 18.0 0.2 2.1 2 0 0 2 2 2 1 VirC1 protein ATP_bind_1 PF03029.17 EMT52684.1 - 0.012 15.4 0.3 0.8 9.4 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EMT52684.1 - 0.015 15.1 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 EMT52684.1 - 0.036 13.0 0.3 0.067 12.2 0.3 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FTHFS PF01268.19 EMT52684.1 - 0.13 10.5 0.3 0.2 9.8 0.3 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase ParBc PF02195.18 EMT52686.1 - 2e-28 98.5 0.2 4.4e-28 97.4 0.2 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_ParB PF17762.1 EMT52686.1 - 6.9e-17 61.0 3.5 6.9e-17 61.0 3.5 2.2 3 0 0 3 3 3 1 HTH domain found in ParB protein HTH_3 PF01381.22 EMT52686.1 - 0.006 16.6 0.1 0.015 15.4 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_50 PF18024.1 EMT52686.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MgtC PF02308.16 EMT52687.1 - 3.8e-35 120.9 7.3 4.7e-35 120.6 7.3 1.1 1 0 0 1 1 1 1 MgtC family GidB PF02527.15 EMT52688.1 - 4e-56 189.2 0.0 4.7e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.12 EMT52688.1 - 0.0027 18.4 0.0 0.21 12.3 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT52688.1 - 0.0036 18.0 0.0 0.039 14.7 0.0 2.3 2 1 1 3 3 3 1 Methyltransferase domain MTS PF05175.14 EMT52688.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RraB PF06877.11 EMT52688.1 - 0.18 12.5 1.0 0.59 10.9 0.3 2.0 2 0 0 2 2 2 0 Regulator of ribonuclease activity B GIDA PF01134.22 EMT52689.1 - 6.3e-173 575.4 0.0 8.5e-173 574.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EMT52689.1 - 3.4e-79 265.9 2.8 5.7e-79 265.2 2.8 1.4 1 0 0 1 1 1 1 GidA associated domain FAD_binding_2 PF00890.24 EMT52689.1 - 1.2e-07 31.2 5.6 0.003 16.7 0.1 2.9 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 EMT52689.1 - 2e-05 24.0 1.4 0.00016 21.0 1.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMT52689.1 - 2.7e-05 23.7 0.2 7.5e-05 22.2 0.2 1.9 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EMT52689.1 - 0.0019 17.9 1.9 0.2 11.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMT52689.1 - 0.0051 16.1 0.4 0.72 9.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMT52689.1 - 0.017 14.4 0.0 0.059 12.7 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EMT52689.1 - 0.029 13.1 2.6 0.18 10.5 0.2 3.0 4 0 0 4 4 4 0 HI0933-like protein ThiF PF00899.21 EMT52689.1 - 0.076 12.4 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 ThiF family MnmE_helical PF12631.7 EMT52690.1 - 5.7e-63 212.8 5.1 7.2e-63 212.5 5.1 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EMT52690.1 - 3e-41 140.4 0.1 8.1e-41 139.0 0.0 1.8 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EMT52690.1 - 1.8e-24 86.0 0.6 3.8e-24 84.9 0.2 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMT52690.1 - 6.8e-11 41.9 0.3 1.3e-10 41.0 0.3 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EMT52690.1 - 1.2e-07 31.8 0.1 0.002 18.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EMT52690.1 - 1.8e-07 31.3 0.2 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.16 EMT52690.1 - 1.3e-06 27.9 0.1 2.4e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 EMT52690.1 - 2.1e-05 24.2 0.0 7.4e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 EMT52690.1 - 0.00013 21.6 0.0 0.073 12.6 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 EMT52690.1 - 0.00054 19.9 0.1 0.002 18.1 0.1 2.1 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Roc PF08477.13 EMT52690.1 - 0.0056 16.9 0.0 0.016 15.4 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EMT52690.1 - 0.031 14.6 0.9 0.11 12.9 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EMT52690.1 - 0.044 14.3 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Jag_N PF14804.6 EMT52691.1 - 8.8e-21 74.0 0.3 1.5e-20 73.3 0.3 1.4 1 0 0 1 1 1 1 Jag N-terminus KH_4 PF13083.6 EMT52691.1 - 7.7e-16 57.7 2.8 1.1e-15 57.2 0.3 2.5 3 1 1 4 4 4 1 KH domain R3H PF01424.22 EMT52691.1 - 2.4e-15 56.3 0.2 5.1e-15 55.2 0.2 1.6 1 0 0 1 1 1 1 R3H domain KH_2 PF07650.17 EMT52691.1 - 0.0024 17.6 0.1 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 KH domain YwhD PF08741.10 EMT52691.1 - 0.0029 17.3 0.1 0.0054 16.4 0.1 1.5 1 0 0 1 1 1 1 YwhD family SieB PF14163.6 EMT52691.1 - 0.084 12.4 0.2 0.15 11.5 0.2 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B 60KD_IMP PF02096.20 EMT52692.1 - 1.3e-60 204.1 13.7 1.6e-60 203.8 13.7 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Vpu PF00558.19 EMT52692.1 - 0.022 14.5 0.0 0.022 14.5 0.0 1.7 2 0 0 2 2 2 0 Vpu protein LPAM_1 PF08139.12 EMT52692.1 - 0.19 12.3 0.3 0.19 12.3 0.3 2.7 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site DUF4834 PF16118.5 EMT52692.1 - 0.24 12.4 0.9 4.7 8.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) YidD PF01809.18 EMT52693.1 - 1.7e-32 111.1 0.2 1.9e-32 111.0 0.2 1.0 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor Ribonuclease_P PF00825.18 EMT52694.1 - 3e-34 117.4 1.9 3.4e-34 117.2 1.9 1.0 1 0 0 1 1 1 1 Ribonuclease P Ribosomal_L34 PF00468.17 EMT52696.1 - 3.4e-22 78.2 10.0 3.6e-22 78.1 10.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 Bac_DnaA PF00308.18 EMT52697.1 - 5.9e-109 363.0 0.1 1e-108 362.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 EMT52697.1 - 9.5e-31 105.6 0.1 1e-29 102.4 0.0 2.3 2 0 0 2 2 2 1 Bacterial dnaA protein helix-turn-helix DnaA_N PF11638.8 EMT52697.1 - 7.8e-18 64.0 0.3 1.6e-17 63.0 0.3 1.6 1 0 0 1 1 1 1 DnaA N-terminal domain IstB_IS21 PF01695.17 EMT52697.1 - 4.1e-12 46.2 0.0 8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 EMT52697.1 - 1.5e-06 28.7 0.0 4.6e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 EMT52697.1 - 0.00021 20.3 0.3 0.073 11.9 0.1 2.3 1 1 0 2 2 2 2 AFG1-like ATPase ATPase_2 PF01637.18 EMT52697.1 - 0.00053 20.0 0.8 0.0014 18.6 0.3 1.9 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EMT52697.1 - 0.00055 20.3 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EMT52697.1 - 0.00056 19.9 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DNA_pol3_a_NII PF11490.8 EMT52697.1 - 0.0044 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III polC-type N-terminus II AAA_22 PF13401.6 EMT52697.1 - 0.0045 17.3 0.5 4.6 7.5 0.1 3.0 2 1 1 3 3 2 2 AAA domain DUF4780 PF16012.5 EMT52697.1 - 0.05 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) DUF2075 PF09848.9 EMT52697.1 - 0.068 12.4 0.2 2.1 7.5 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EMT52697.1 - 0.085 13.2 0.1 0.43 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_35 PF14516.6 EMT52697.1 - 0.11 11.3 0.0 4.8 5.9 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain DNA_pol3_beta PF00712.19 EMT52698.1 - 1.1e-47 161.1 1.0 4.5e-35 120.4 0.2 3.2 3 0 0 3 3 3 3 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_2 PF02767.16 EMT52698.1 - 9.1e-41 138.7 0.3 1.7e-31 108.8 0.0 2.7 2 1 0 2 2 2 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta_3 PF02768.15 EMT52698.1 - 6.3e-36 122.9 0.7 5.4e-33 113.4 0.0 2.9 3 0 0 3 3 3 2 DNA polymerase III beta subunit, C-terminal domain S4_2 PF13275.6 EMT52699.1 - 8.7e-28 95.9 0.0 9.4e-28 95.8 0.0 1.0 1 0 0 1 1 1 1 S4 domain SMC_N PF02463.19 EMT52700.1 - 3e-15 56.2 0.0 6.6e-15 55.1 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT52700.1 - 1.3e-08 34.9 0.1 5.1e-08 33.0 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EMT52700.1 - 8e-08 33.0 0.1 1.1e-07 32.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EMT52700.1 - 1.6e-05 24.9 0.2 0.041 13.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4570 PF15134.6 EMT52700.1 - 0.037 14.0 0.4 0.087 12.8 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF370 PF04025.12 EMT52701.1 - 1.2e-13 51.0 0.4 1.5e-13 50.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF370) PP-binding_2 PF14573.6 EMT52701.1 - 0.02 15.1 1.1 4.8 7.5 0.0 2.1 1 1 1 2 2 2 0 Acyl-carrier MBD PF01429.19 EMT52701.1 - 0.044 13.5 0.1 4 7.2 0.0 2.1 1 1 1 2 2 2 0 Methyl-CpG binding domain DNA_gyraseB PF00204.25 EMT52702.1 - 5.7e-66 221.3 0.2 1e-65 220.5 0.2 1.4 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 EMT52702.1 - 1.2e-30 105.5 0.1 2.6e-30 104.4 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 EMT52702.1 - 1.8e-23 83.1 0.2 4.2e-23 82.0 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EMT52702.1 - 9.9e-19 67.5 0.0 2.5e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 EMT52702.1 - 0.0027 17.5 0.1 0.0069 16.2 0.1 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LMWPc PF01451.21 EMT52703.1 - 1.4e-23 83.9 0.0 1.6e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase ArsB PF02040.15 EMT52704.1 - 1.7e-209 696.4 31.7 1.9e-209 696.2 31.7 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.16 EMT52704.1 - 5.5e-28 98.0 32.7 5.5e-28 98.0 32.7 1.7 1 1 1 2 2 2 1 Citrate transporter Na_sulph_symp PF00939.19 EMT52704.1 - 1.4e-09 37.5 34.3 2.1e-05 23.8 13.3 2.3 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region T2SSM_b PF10741.9 EMT52704.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b MLTD_N PF06474.12 EMT52704.1 - 4.6 7.5 6.8 0.54 10.5 0.3 2.8 2 0 0 2 2 2 0 MltD lipid attachment motif HTH_5 PF01022.20 EMT52705.1 - 1.1e-15 57.2 0.2 1e-14 54.1 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EMT52705.1 - 1.4e-09 37.8 0.0 1.6e-08 34.4 0.0 2.2 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 EMT52705.1 - 0.022 14.3 0.1 1.5 8.5 0.0 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding PaaX PF07848.12 EMT52705.1 - 0.025 14.8 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein Rrf2 PF02082.20 EMT52705.1 - 0.058 13.7 0.0 0.2 12.0 0.0 2.0 1 1 1 2 2 2 0 Transcriptional regulator HTH_11 PF08279.12 EMT52705.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.6 1 1 0 1 1 1 0 HTH domain ABC_tran PF00005.27 EMT52707.1 - 3.1e-42 144.3 8.7 1.8e-22 80.4 0.1 4.8 4 2 1 5 5 4 3 ABC transporter AAA_21 PF13304.6 EMT52707.1 - 2.6e-10 40.6 15.6 0.013 15.4 0.3 5.1 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT52707.1 - 9e-08 31.8 0.3 0.013 15.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran_Xtn PF12848.7 EMT52707.1 - 1.3e-07 31.5 36.5 3.2e-05 23.9 23.1 4.0 2 2 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EMT52707.1 - 1.9e-07 31.1 0.2 0.026 14.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMT52707.1 - 5.2e-07 29.7 1.6 0.0039 17.3 0.0 3.5 2 2 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 EMT52707.1 - 1.7e-06 27.7 7.7 0.48 9.8 0.0 4.4 4 1 1 5 5 4 3 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.25 EMT52707.1 - 4.6e-06 26.4 0.0 0.0071 16.0 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 EMT52707.1 - 4.4e-05 22.8 0.2 0.04 13.1 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 EMT52707.1 - 6.1e-05 23.0 0.9 0.26 11.2 0.1 2.7 2 1 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EMT52707.1 - 0.00016 21.9 0.4 0.23 11.8 0.0 3.0 2 2 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EMT52707.1 - 0.00034 20.9 6.5 0.0087 16.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_15 PF13175.6 EMT52707.1 - 0.00042 20.1 13.1 0.15 11.7 3.8 3.8 3 1 0 3 3 3 2 AAA ATPase domain Roc PF08477.13 EMT52707.1 - 0.00087 19.5 0.1 1.1 9.6 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EMT52707.1 - 0.0012 18.6 0.1 0.21 11.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EMT52707.1 - 0.0015 17.6 0.6 1.2 8.1 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 EMT52707.1 - 0.0016 18.0 0.1 0.34 10.4 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RNA_helicase PF00910.22 EMT52707.1 - 0.0025 18.2 0.2 2 8.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 EMT52707.1 - 0.0025 18.2 0.1 2.5 8.5 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EMT52707.1 - 0.0039 16.9 0.4 1.4 8.7 0.1 2.7 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 EMT52707.1 - 0.004 17.6 6.0 0.23 11.8 0.7 3.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EMT52707.1 - 0.0066 16.5 0.1 1.6 8.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 EMT52707.1 - 0.011 15.7 0.2 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 SbcCD_C PF13558.6 EMT52707.1 - 0.011 15.9 0.5 3.2 8.0 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.15 EMT52707.1 - 0.012 15.5 0.4 3.4 7.6 0.1 2.8 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 EMT52707.1 - 0.015 15.1 4.4 1.4 8.6 0.1 3.0 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 EMT52707.1 - 0.032 14.6 1.4 0.19 12.1 0.0 2.8 3 1 0 3 3 3 0 AAA domain AFG1_ATPase PF03969.16 EMT52707.1 - 0.046 12.6 1.6 0.11 11.3 0.0 2.3 2 1 0 3 3 3 0 AFG1-like ATPase DAP3 PF10236.9 EMT52707.1 - 0.048 12.8 0.5 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Ras PF00071.22 EMT52707.1 - 0.06 12.9 1.8 6 6.4 0.1 2.6 2 0 0 2 2 2 0 Ras family AAA_7 PF12775.7 EMT52707.1 - 0.073 12.6 0.1 6.4 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 EMT52707.1 - 0.11 12.7 4.6 6.9 6.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EMT52707.1 - 0.12 12.3 0.5 6.8 6.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.27 EMT52707.1 - 0.14 11.7 0.3 16 4.9 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 EMT52707.1 - 0.15 11.6 0.4 25 4.4 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EMT52707.1 - 0.17 12.4 29.9 0.37 11.3 0.0 4.1 3 2 0 3 3 2 0 AAA domain AAA_18 PF13238.6 EMT52707.1 - 0.68 10.5 13.4 3.7 8.1 0.4 4.5 2 2 1 3 3 3 0 AAA domain Dynamin_N PF00350.23 EMT52707.1 - 2.3 8.2 6.8 35 4.4 0.0 3.5 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 EMT52707.1 - 5.6 6.7 4.8 20 4.9 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein MFS_1 PF07690.16 EMT52708.1 - 3.1e-43 148.1 55.1 3.9e-30 105.0 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT52708.1 - 4e-12 45.7 27.5 1.3e-07 30.8 12.8 2.1 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 EMT52708.1 - 1.2e-10 40.8 12.9 1.2e-10 40.8 12.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 EMT52708.1 - 6.8e-06 24.9 12.0 6.8e-06 24.9 12.0 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein PUCC PF03209.15 EMT52708.1 - 2.3e-05 23.6 2.6 2.3e-05 23.6 2.6 2.8 2 1 1 3 3 3 2 PUCC protein MFS_3 PF05977.13 EMT52708.1 - 0.0024 16.3 21.0 0.0098 14.3 21.0 1.8 1 1 0 1 1 1 1 Transmembrane secretion effector DNA_topoisoIV PF00521.20 EMT52709.1 - 2.9e-165 550.3 1.0 3.7e-165 550.0 1.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 EMT52709.1 - 3.5e-79 260.1 18.9 1.9e-14 52.8 0.5 6.5 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller NTase_sub_bind PF08780.11 EMT52709.1 - 0.011 15.7 0.8 0.025 14.5 0.8 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like ANTAR PF03861.14 EMT52709.1 - 0.059 13.2 0.1 2.5 8.0 0.0 3.2 3 0 0 3 3 3 0 ANTAR domain HD_5 PF13487.6 EMT52710.1 - 4.4e-15 55.7 0.1 8.9e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 HD domain HD PF01966.22 EMT52710.1 - 1.6e-14 54.2 0.1 2.8e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 EMT52710.1 - 0.043 13.3 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 HDOD domain HTH_41 PF14502.6 EMT52710.1 - 0.13 11.9 0.0 0.92 9.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain YopX PF09643.10 EMT52711.1 - 2.7e-18 66.3 0.1 3.4e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 YopX protein DUF4873 PF16170.5 EMT52712.1 - 0.15 12.3 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4873) Sigma70_r2 PF04542.14 EMT52715.1 - 4e-15 55.3 0.0 5.4e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Sigma-70 region 2 zf-CCCH_7 PF18586.1 EMT52715.1 - 0.097 13.0 0.0 0.33 11.3 0.0 1.8 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 DUF4131 PF13567.6 EMT52716.1 - 0.82 9.3 5.3 0.94 9.1 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4624 PF15417.6 EMT52717.1 - 0.012 15.4 0.4 0.031 14.1 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4624) DUF2408 PF10303.9 EMT52717.1 - 0.018 15.6 3.6 0.018 15.6 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) CREPT PF16566.5 EMT52717.1 - 0.21 11.8 7.3 0.78 9.9 2.0 2.5 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DHR10 PF18595.1 EMT52717.1 - 0.33 11.0 23.5 1 9.5 8.2 3.3 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 EMT52717.1 - 1.6 7.5 22.6 0.76 8.6 5.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein LUC7 PF03194.15 EMT52717.1 - 3.6 7.2 18.7 6.3 6.4 2.8 2.2 1 1 1 2 2 2 0 LUC7 N_terminus DUF572 PF04502.13 EMT52717.1 - 9.4 5.7 13.1 12 5.4 13.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MCPsignal PF00015.21 EMT52718.1 - 5.9e-50 169.4 27.2 5.9e-50 169.4 27.2 5.0 2 2 4 6 6 6 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 EMT52718.1 - 4.3e-15 55.8 0.1 4.3e-15 55.8 0.1 5.1 6 1 0 6 6 6 1 HAMP domain 4HB_MCP_1 PF12729.7 EMT52718.1 - 1.4e-13 50.8 9.0 1.4e-13 50.8 9.0 5.0 5 0 0 5 5 5 1 Four helix bundle sensory module for signal transduction BLOC1_2 PF10046.9 EMT52718.1 - 0.00056 20.2 0.5 0.00056 20.2 0.5 6.4 4 3 3 7 7 7 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 Abi_C PF14355.6 EMT52718.1 - 0.0038 17.3 3.4 0.9 9.7 0.1 4.3 3 1 1 4 4 4 1 Abortive infection C-terminus RP-C PF03428.13 EMT52718.1 - 0.056 13.1 0.1 0.056 13.1 0.1 4.0 4 1 1 5 5 5 0 Replication protein C N-terminal domain DUF948 PF06103.11 EMT52718.1 - 0.22 11.8 46.6 2.2 8.6 5.6 7.1 3 3 3 6 6 6 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 EMT52718.1 - 2.1 8.7 33.0 0.17 12.3 0.6 6.4 2 2 4 6 6 6 0 Syntaxin-like protein SCO1-SenC PF02630.14 EMT52718.1 - 2.4 8.1 5.1 7.2 6.5 0.3 3.3 4 0 0 4 4 4 0 SCO1/SenC DUF1664 PF07889.12 EMT52718.1 - 3 7.9 40.0 2.2 8.3 1.8 5.8 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.13 EMT52718.1 - 7 7.2 14.9 17 6.0 2.6 4.8 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Herpes_ICP4_N PF03584.15 EMT52718.1 - 7.6 6.3 8.7 17 5.2 1.3 3.3 3 0 0 3 3 3 0 Herpesvirus ICP4-like protein N-terminal region Acetyltransf_1 PF00583.25 EMT52719.1 - 2.8e-17 63.0 0.1 4.5e-17 62.4 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT52719.1 - 1.8e-14 53.8 0.4 3e-13 49.8 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT52719.1 - 4.5e-11 43.0 0.1 7.3e-11 42.3 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT52719.1 - 2.3e-09 37.1 0.0 4.6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EMT52719.1 - 5.6e-06 26.1 0.1 1.1e-05 25.2 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT52719.1 - 0.00038 20.6 0.0 0.00066 19.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMT52719.1 - 0.00057 20.6 0.0 0.001 19.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT52719.1 - 0.00079 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EMT52719.1 - 0.021 14.9 0.1 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EMT52719.1 - 0.13 11.7 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase HD PF01966.22 EMT52720.1 - 2.8e-16 59.8 0.0 6.3e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 EMT52720.1 - 3.3e-12 46.5 0.1 1.9e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 EMT52720.1 - 0.002 17.7 0.1 0.0046 16.5 0.0 1.7 1 1 1 2 2 2 1 HDOD domain Prok-JAB PF14464.6 EMT52721.1 - 1.1e-08 34.9 0.1 1.3e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Transpeptidase PF00905.22 EMT52722.1 - 2.6e-63 214.1 0.0 4.4e-63 213.3 0.0 1.4 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 EMT52722.1 - 7.9e-12 45.9 0.0 1.6e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain Beta-lactamase2 PF13354.6 EMT52722.1 - 5.5e-06 26.1 0.0 2.2e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase enzyme family PRK PF00485.18 EMT52723.1 - 1.2e-46 159.0 0.3 1.4e-46 158.7 0.3 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EMT52723.1 - 2e-07 31.6 0.1 3.4e-07 30.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EMT52723.1 - 1.3e-05 24.6 0.1 5.3e-05 22.6 0.0 2.0 2 1 1 3 3 3 1 Zeta toxin AAA_33 PF13671.6 EMT52723.1 - 0.00012 22.3 0.0 0.00028 21.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain Cytidylate_kin PF02224.18 EMT52723.1 - 0.00033 20.5 0.4 0.086 12.6 0.0 2.3 1 1 1 2 2 2 2 Cytidylate kinase AAA_22 PF13401.6 EMT52723.1 - 0.00034 20.9 0.0 0.00056 20.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 EMT52723.1 - 0.00062 19.5 3.0 0.0086 15.8 3.0 2.1 1 1 0 1 1 1 1 Dephospho-CoA kinase ABC_tran PF00005.27 EMT52723.1 - 0.00079 20.0 0.0 0.001 19.6 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_17 PF13207.6 EMT52723.1 - 0.0011 19.4 0.7 0.33 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMT52723.1 - 0.0013 19.1 0.0 0.0024 18.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 EMT52723.1 - 0.0056 16.7 0.0 0.0087 16.1 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 EMT52723.1 - 0.0066 16.1 0.3 0.27 10.9 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase dNK PF01712.19 EMT52723.1 - 0.0068 16.3 0.3 0.038 13.9 0.3 1.9 1 1 0 1 1 1 1 Deoxynucleoside kinase APS_kinase PF01583.20 EMT52723.1 - 0.0085 16.0 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 2 1 Adenylylsulphate kinase MobB PF03205.14 EMT52723.1 - 0.017 15.0 0.1 0.23 11.4 0.0 2.4 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EMT52723.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EMT52723.1 - 0.023 13.9 0.0 0.043 13.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 EMT52723.1 - 0.026 14.3 0.0 0.056 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMT52723.1 - 0.031 14.7 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 EMT52723.1 - 0.036 13.3 0.0 0.06 12.6 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.6 EMT52723.1 - 0.041 14.1 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EMT52723.1 - 0.053 12.7 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 EMT52723.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EMT52723.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 EMT52723.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Methyltransf_3 PF01596.17 EMT52724.1 - 3.1e-29 101.7 0.0 3.8e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EMT52724.1 - 4.3e-15 56.6 0.0 6.1e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT52724.1 - 3.2e-10 40.0 0.0 4.1e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT52724.1 - 4.2e-10 40.2 0.0 6.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMT52724.1 - 3.5e-09 36.7 0.0 6.1e-09 35.9 0.0 1.3 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EMT52724.1 - 7e-07 29.3 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMT52724.1 - 1.5e-06 27.8 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EMT52724.1 - 4.9e-06 27.1 0.0 8.2e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 EMT52724.1 - 1.2e-05 25.1 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltr_RsmB-F PF01189.17 EMT52724.1 - 2.2e-05 24.2 0.0 3.6e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 EMT52724.1 - 7.4e-05 22.2 0.0 0.00012 21.5 0.0 1.2 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EMT52724.1 - 0.0003 21.5 0.0 0.00058 20.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EMT52724.1 - 0.00052 19.8 0.0 0.0007 19.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.17 EMT52724.1 - 0.00061 19.3 0.0 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase UPF0020 PF01170.18 EMT52724.1 - 0.00077 19.2 0.0 0.00097 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DUF938 PF06080.12 EMT52724.1 - 0.0049 16.7 0.0 0.0069 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 EMT52724.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EMT52724.1 - 0.052 12.9 0.0 0.062 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EMT52724.1 - 0.19 11.5 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EMT52724.1 - 0.23 11.2 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein YceG PF02618.16 EMT52725.1 - 4.8e-92 308.4 0.1 5.6e-92 308.2 0.1 1.0 1 0 0 1 1 1 1 YceG-like family ApbA_C PF08546.11 EMT52725.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DUF1292 PF06949.11 EMT52728.1 - 6.2e-15 55.9 8.3 6.2e-15 55.9 8.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1292) DUF2513 PF10711.9 EMT52728.1 - 0.0048 17.2 0.0 0.0052 17.1 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2513) EPL1 PF10513.9 EMT52728.1 - 7.8 6.9 7.5 10 6.5 7.5 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like RuvX PF03652.15 EMT52729.1 - 3.3e-47 160.2 0.0 3.7e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Holliday junction resolvase IreB PF06135.12 EMT52730.1 - 1.1e-35 121.7 0.1 1.2e-35 121.5 0.1 1.0 1 0 0 1 1 1 1 IreB regulatory phosphoprotein CHASE3 PF05227.13 EMT52730.1 - 0.032 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 CHASE3 domain DYW_deaminase PF14432.6 EMT52730.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.3 1 1 0 1 1 1 0 DYW family of nucleic acid deaminases tRNA-synt_2c PF01411.19 EMT52731.1 - 7.1e-212 704.8 0.0 8.9e-212 704.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 EMT52731.1 - 2.3e-31 109.0 2.5 6.8e-31 107.5 2.5 1.9 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 EMT52731.1 - 1e-18 67.2 0.5 1e-18 67.2 0.5 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain Spc7 PF08317.11 EMT52731.1 - 0.0088 15.0 0.3 0.018 14.0 0.3 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein HAP1_N PF04849.13 EMT52731.1 - 0.047 12.9 1.3 0.078 12.2 1.3 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region GTP_EFTU_D2 PF03144.25 EMT52731.1 - 0.064 13.7 1.3 0.46 10.9 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu domain 2 CENP-F_leu_zip PF10473.9 EMT52731.1 - 0.069 13.2 0.5 0.16 12.0 0.5 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 EMT52731.1 - 7.9 6.6 12.0 13 6.0 2.7 3.4 2 1 1 3 3 3 0 TolA binding protein trimerisation AI-2E_transport PF01594.16 EMT52733.1 - 4.9e-81 272.4 29.5 8e-81 271.7 29.4 1.4 1 1 0 1 1 1 1 AI-2E family transporter TerC PF03741.16 EMT52734.1 - 4.3e-44 150.3 17.4 4.3e-44 150.3 17.4 1.9 1 1 1 2 2 2 1 Integral membrane protein TerC family SIS PF01380.22 EMT52735.1 - 7.4e-14 51.7 0.1 1.2e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 EMT52735.1 - 1.3e-10 41.1 0.0 2.5e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family YtxH PF12732.7 EMT52736.1 - 0.049 14.2 0.1 0.059 13.9 0.1 1.3 1 1 0 1 1 1 0 YtxH-like protein zf-RRPl_C4 PF17026.5 EMT52737.1 - 0.01 15.9 0.6 0.012 15.7 0.6 1.1 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn_Tnp_IS1595 PF12760.7 EMT52737.1 - 0.016 15.2 1.3 0.024 14.6 1.3 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EMT52737.1 - 0.035 13.6 1.2 0.078 12.5 1.2 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 EMT52737.1 - 0.067 13.1 3.1 0.33 10.9 1.1 2.4 2 1 0 2 2 2 0 zinc-ribbon domain PRC PF05239.16 EMT52738.1 - 4.1e-18 65.2 0.5 5.3e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 PRC-barrel domain AAA_30 PF13604.6 EMT52739.1 - 6e-49 166.4 0.0 1.1e-48 165.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMT52739.1 - 1e-38 133.0 0.0 2.4e-38 131.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain HHH_4 PF14490.6 EMT52739.1 - 1.6e-34 117.8 0.1 5.6e-30 103.2 0.1 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix containing domain SH3_13 PF18335.1 EMT52739.1 - 6e-22 77.2 1.0 1.1e-21 76.5 1.0 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain UvrD_C_2 PF13538.6 EMT52739.1 - 1.3e-14 53.7 0.0 4.5e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain HHH_5 PF14520.6 EMT52739.1 - 3.7e-12 46.7 0.4 3.8e-07 30.6 0.1 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix domain AAA_11 PF13086.6 EMT52739.1 - 3.2e-10 40.2 0.1 1.2e-06 28.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EMT52739.1 - 2e-08 34.3 0.7 0.0029 17.4 0.4 3.5 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase HHH PF00633.23 EMT52739.1 - 1.1e-06 28.1 0.3 0.011 15.6 0.1 3.7 3 0 0 3 3 3 1 Helix-hairpin-helix motif AAA PF00004.29 EMT52739.1 - 0.00043 20.7 0.4 0.0097 16.3 0.1 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 EMT52739.1 - 0.0006 19.4 0.1 0.028 13.9 0.0 2.3 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 EMT52739.1 - 0.0012 19.3 0.0 0.0061 16.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT52739.1 - 0.0017 18.6 0.2 0.0069 16.7 0.2 2.0 1 1 0 1 1 1 1 AAA domain HHH_3 PF12836.7 EMT52739.1 - 0.0027 17.9 0.1 5.7 7.3 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_2 PF12826.7 EMT52739.1 - 0.0046 17.0 0.1 0.7 10.0 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif T2SSE PF00437.20 EMT52739.1 - 0.0055 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein TsaE PF02367.17 EMT52739.1 - 0.026 14.5 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 EMT52739.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EMT52739.1 - 0.065 13.1 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 EMT52739.1 - 0.071 12.9 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EMT52739.1 - 0.089 13.0 0.3 0.21 11.8 0.3 1.6 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.6 EMT52739.1 - 0.094 12.3 0.0 0.2 11.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain UvrD_C PF13361.6 EMT52739.1 - 0.099 12.0 0.1 0.35 10.2 0.1 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Ribosomal_S13 PF00416.22 EMT52739.1 - 0.12 12.8 0.4 8.6 6.8 0.1 2.8 1 1 2 3 3 3 0 Ribosomal protein S13/S18 Mg_chelatase PF01078.21 EMT52739.1 - 0.12 11.7 0.1 0.33 10.3 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EMT52739.1 - 0.13 11.5 0.0 0.95 8.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin HTH_IclR PF09339.10 EMT52739.1 - 0.55 10.1 1.9 8.3 6.3 0.5 2.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain MbeD_MobD PF04899.12 EMT52740.1 - 0.011 15.8 0.1 0.013 15.6 0.1 1.2 1 0 0 1 1 1 0 MbeD/MobD like PSD4 PF07631.11 EMT52740.1 - 0.051 14.1 1.1 0.052 14.1 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) Aminotran_5 PF00266.19 EMT52741.1 - 7e-85 285.2 0.1 8.5e-85 284.9 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMT52741.1 - 1.6e-07 30.9 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EMT52741.1 - 0.014 14.6 0.0 0.06 12.5 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class I and II Pyridoxal_deC PF00282.19 EMT52741.1 - 0.027 13.2 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain B12-binding PF02310.19 EMT52741.1 - 0.033 14.2 0.0 0.14 12.2 0.0 2.1 2 1 0 2 2 2 0 B12 binding domain FumaraseC_C PF10415.9 EMT52741.1 - 0.043 14.2 0.1 0.84 10.1 0.0 2.5 2 0 0 2 2 2 0 Fumarase C C-terminus Rrf2 PF02082.20 EMT52742.1 - 2e-29 101.7 0.1 2.8e-29 101.3 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 EMT52742.1 - 0.0021 17.9 0.1 0.016 15.1 0.0 2.1 1 1 1 2 2 2 1 MarR family HrcA_DNA-bdg PF03444.15 EMT52742.1 - 0.011 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding RuvB_C PF05491.13 EMT52742.1 - 0.046 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain MgsA_C PF12002.8 EMT52743.1 - 8e-72 240.6 0.0 1.2e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EMT52743.1 - 5.1e-29 100.4 0.1 4.3e-28 97.5 0.1 2.3 2 0 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 EMT52743.1 - 3e-17 63.3 0.0 1.1e-16 61.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMT52743.1 - 3.5e-14 52.9 0.0 6.6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EMT52743.1 - 6.2e-08 32.5 0.0 0.0004 20.1 0.0 2.3 1 1 1 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 EMT52743.1 - 8.1e-07 29.1 0.1 1.1e-05 25.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMT52743.1 - 4.5e-06 26.2 0.1 0.0095 15.3 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EMT52743.1 - 6.4e-06 26.2 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT52743.1 - 6.8e-06 26.6 1.8 0.00063 20.2 1.8 3.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.11 EMT52743.1 - 4.1e-05 23.4 0.0 0.0001 22.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EMT52743.1 - 0.0001 22.1 0.0 0.1 12.4 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA_2 PF07724.14 EMT52743.1 - 0.00013 22.1 0.0 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EMT52743.1 - 0.00017 21.9 0.3 0.0033 17.7 0.3 2.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EMT52743.1 - 0.00031 21.3 0.0 0.00057 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMT52743.1 - 0.00032 21.0 0.4 0.0012 19.2 0.4 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EMT52743.1 - 0.00048 20.3 0.0 0.00092 19.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 EMT52743.1 - 0.00069 19.4 0.3 0.011 15.4 0.3 2.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EMT52743.1 - 0.0037 17.6 0.0 0.0074 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 EMT52743.1 - 0.0046 17.1 0.3 0.012 15.8 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EMT52743.1 - 0.0047 16.7 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EMT52743.1 - 0.011 15.0 0.0 0.03 13.6 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 EMT52743.1 - 0.011 16.2 0.0 0.024 15.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EMT52743.1 - 0.013 15.8 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EMT52743.1 - 0.015 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EMT52743.1 - 0.016 15.1 0.0 0.65 9.9 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EMT52743.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 EMT52743.1 - 0.022 14.7 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 EMT52743.1 - 0.022 13.9 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.15 EMT52743.1 - 0.045 13.7 0.1 6.1 6.8 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EMT52743.1 - 0.047 13.3 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EMT52743.1 - 0.048 12.3 0.0 0.085 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EMT52743.1 - 0.051 12.7 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 EMT52743.1 - 0.069 13.6 0.2 0.4 11.1 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EMT52743.1 - 0.087 12.6 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EMT52743.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 EMT52743.1 - 0.097 11.8 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ATPase PF06745.13 EMT52743.1 - 0.097 12.0 0.5 9.2 5.5 0.0 2.3 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 EMT52743.1 - 0.14 11.6 0.1 0.5 9.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein SKI PF01202.22 EMT52743.1 - 0.16 12.0 0.0 0.71 10.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase AAA_7 PF12775.7 EMT52743.1 - 0.22 11.0 0.0 0.53 9.8 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region ThiF PF00899.21 EMT52744.1 - 6.8e-38 130.4 0.1 7.5e-38 130.3 0.1 1.1 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 EMT52744.1 - 0.0017 18.0 1.0 0.0027 17.3 1.0 1.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 EMT52744.1 - 0.0065 16.9 0.2 0.022 15.2 0.1 1.8 1 1 1 2 2 2 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EMT52744.1 - 0.016 15.5 1.2 0.032 14.5 1.2 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EMT52744.1 - 0.052 13.6 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EMT52744.1 - 0.077 12.4 1.3 0.35 10.2 1.2 1.9 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EMT52744.1 - 0.08 12.8 0.9 0.15 11.9 0.9 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HHH_5 PF14520.6 EMT52744.1 - 0.13 12.9 0.4 0.33 11.6 0.4 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain tRNA-synt_2 PF00152.20 EMT52745.1 - 5e-112 374.0 0.0 5.9e-112 373.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 EMT52745.1 - 1.6e-28 98.8 0.2 3.1e-28 97.8 0.2 1.5 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 EMT52745.1 - 3.2e-16 59.1 0.6 7.1e-16 58.0 0.6 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMT52745.1 - 2.7e-05 23.8 0.1 0.0046 16.5 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_His PF13393.6 EMT52746.1 - 1.1e-45 156.3 0.2 1.9e-45 155.5 0.0 1.5 2 0 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EMT52746.1 - 6.1e-17 61.6 0.1 1.8e-15 56.9 0.1 2.6 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EMT52746.1 - 9.4e-17 61.6 0.0 3.4e-16 59.7 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_synthFbeta PF17759.1 EMT52746.1 - 4e-06 26.4 0.0 1e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2d PF01409.20 EMT52746.1 - 0.001 18.6 0.0 0.032 13.7 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) zf-tcix PF14952.6 EMT52746.1 - 0.025 14.2 0.5 0.06 13.0 0.5 1.6 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Radical_SAM PF04055.21 EMT52747.1 - 3.5e-17 63.3 0.1 7.3e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily DUF4915 PF16261.5 EMT52747.1 - 0.16 11.2 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4915) YpmT PF17431.2 EMT52747.1 - 0.19 11.8 0.0 0.6 10.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized YmpT-like SH3_3 PF08239.11 EMT52750.1 - 9.6e-59 195.5 21.4 1.9e-15 56.9 0.5 5.6 5 0 0 5 5 5 5 Bacterial SH3 domain Amidase_3 PF01520.18 EMT52750.1 - 1.5e-47 162.0 0.6 2.3e-47 161.3 0.6 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase SH3_4 PF06347.13 EMT52750.1 - 9.9e-43 143.8 7.5 1.4e-09 37.7 0.2 5.4 5 0 0 5 5 5 5 Bacterial SH3 domain SH3_16 PF18348.1 EMT52750.1 - 2.7e-14 52.7 0.0 0.00029 20.6 0.0 5.3 5 0 0 5 5 5 3 Bacterial dipeptidyl-peptidase Sh3 domain SH3_1 PF00018.28 EMT52750.1 - 1.1e-09 37.7 7.8 0.0011 18.6 0.1 5.2 5 0 0 5 5 5 3 SH3 domain Myosin_N PF02736.19 EMT52750.1 - 3.1e-05 23.7 7.4 0.67 9.8 0.1 6.0 5 1 1 6 6 6 2 Myosin N-terminal SH3-like domain GW PF13457.6 EMT52750.1 - 0.0091 16.6 17.0 0.21 12.2 0.2 5.3 5 1 0 5 5 5 2 GW (Gly-Tryp) dipeptide domain DUF4920 PF16267.5 EMT52750.1 - 0.18 11.8 0.4 12 5.9 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4920) TetR_N PF00440.23 EMT52751.1 - 2.9e-28 97.4 2.2 1.4e-18 66.4 0.2 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 EMT52751.1 - 2.2e-07 31.1 1.6 2.8e-07 30.8 0.2 1.8 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 EMT52751.1 - 0.0041 17.3 0.5 0.069 13.4 0.1 2.5 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_ISL3 PF13542.6 EMT52751.1 - 0.0082 15.5 0.1 0.04 13.3 0.2 2.1 2 1 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 Gram_pos_anchor PF00746.21 EMT52751.1 - 0.0095 15.8 0.3 0.019 14.9 0.3 1.5 1 0 0 1 1 1 1 LPXTG cell wall anchor motif HTH_23 PF13384.6 EMT52751.1 - 0.13 12.1 0.1 0.35 10.7 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Abhydrolase_1 PF00561.20 EMT52752.1 - 1.5e-26 93.6 0.0 1.9e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMT52752.1 - 6.1e-26 92.4 4.6 7.6e-26 92.1 4.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMT52752.1 - 5.7e-18 65.1 0.0 1.3e-17 63.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EMT52752.1 - 1.1e-06 28.6 0.0 0.0043 16.9 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase FSH1 PF03959.13 EMT52752.1 - 0.00017 21.3 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Ndr PF03096.14 EMT52752.1 - 0.0042 15.8 0.0 0.016 13.9 0.0 1.7 1 1 0 1 1 1 1 Ndr family Chlorophyllase PF07224.11 EMT52752.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase Abhydrolase_4 PF08386.10 EMT52752.1 - 0.019 15.1 0.0 0.051 13.7 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein Chlorophyllase2 PF12740.7 EMT52752.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 EMT52752.1 - 0.15 11.9 0.1 0.72 9.7 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Tyr_Deacylase PF02580.16 EMT52753.1 - 7.6e-59 198.4 0.0 8.4e-59 198.2 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase HD_4 PF13328.6 EMT52754.1 - 4.2e-53 179.3 1.8 2.3e-52 176.9 2.7 1.8 2 0 0 2 2 2 1 HD domain RelA_SpoT PF04607.17 EMT52754.1 - 2.8e-40 137.2 0.0 2.8e-40 137.2 0.0 3.5 3 1 0 3 3 3 1 Region found in RelA / SpoT proteins TGS PF02824.21 EMT52754.1 - 2.8e-23 81.7 0.0 6.9e-23 80.5 0.0 1.7 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 EMT52754.1 - 3.7e-22 78.7 4.8 3.7e-22 78.7 4.8 2.5 3 0 0 3 3 3 1 ACT domain HD PF01966.22 EMT52754.1 - 6.9e-09 36.0 2.9 6.9e-09 36.0 2.9 2.2 2 0 0 2 2 2 1 HD domain ACT PF01842.25 EMT52754.1 - 2.7e-08 33.4 1.0 6.5e-08 32.2 1.0 1.7 1 0 0 1 1 1 1 ACT domain ThiS PF02597.20 EMT52754.1 - 0.0029 18.2 0.0 0.015 16.0 0.0 2.4 1 1 0 1 1 1 1 ThiS family ACT_6 PF13740.6 EMT52754.1 - 0.009 16.0 0.1 0.023 14.7 0.1 1.6 1 0 0 1 1 1 1 ACT domain Pribosyltran PF00156.27 EMT52755.1 - 3.1e-14 52.8 0.0 4e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EMT52755.1 - 0.016 14.6 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase ssDNA-exonuc_C PF10141.9 EMT52756.1 - 7.2e-40 136.8 0.0 1e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Single-strand DNA-specific exonuclease, C terminal domain RecJ_OB PF17768.1 EMT52756.1 - 5e-28 97.5 0.0 9.5e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 RecJ OB domain DHHA1 PF02272.19 EMT52756.1 - 8.5e-22 78.1 0.0 1.7e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 EMT52756.1 - 5.2e-11 42.7 0.0 1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 DHH family Cation_efflux PF01545.21 EMT52757.1 - 1e-49 169.0 4.3 1.3e-49 168.6 4.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EMT52757.1 - 2.8e-21 75.4 3.0 4.9e-21 74.6 3.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter SecD_SecF PF02355.16 EMT52758.1 - 2.2e-61 206.5 12.4 4.1e-61 205.7 12.4 1.4 1 0 0 1 1 1 1 Protein export membrane protein Sec_GG PF07549.14 EMT52758.1 - 3.3e-05 23.2 0.3 8e-05 22.0 0.3 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif Tox-WTIP PF15654.6 EMT52758.1 - 0.085 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif DUF2207 PF09972.9 EMT52758.1 - 0.21 10.3 8.9 0.24 10.1 3.2 2.8 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SecD_SecF PF02355.16 EMT52759.1 - 8.5e-10 38.3 12.4 1.8e-09 37.3 12.4 1.5 1 0 0 1 1 1 1 Protein export membrane protein MMPL PF03176.15 EMT52759.1 - 0.00064 18.7 15.2 0.0011 18.0 15.2 1.4 1 0 0 1 1 1 1 MMPL family Amnionless PF14828.6 EMT52759.1 - 0.051 12.4 0.2 0.097 11.5 0.2 1.4 1 0 0 1 1 1 0 Amnionless Post_transc_reg PF13797.6 EMT52760.1 - 5.2e-22 77.5 0.1 6.4e-22 77.2 0.1 1.1 1 0 0 1 1 1 1 Post-transcriptional regulator Polysacc_synt PF01943.17 EMT52761.1 - 2.8e-40 138.4 36.7 1.5e-39 136.0 19.0 2.4 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 EMT52761.1 - 1.3e-22 80.4 33.9 4.2e-21 75.5 16.1 4.1 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 EMT52761.1 - 5.7e-14 52.1 22.8 4.1e-10 39.5 9.7 3.7 3 2 0 3 3 3 2 MatE Polysacc_synt_3 PF13440.6 EMT52761.1 - 7.7e-10 38.5 16.5 7.7e-10 38.5 16.5 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein MurJ PF03023.14 EMT52761.1 - 6.1e-08 31.7 30.7 6.1e-08 31.7 30.7 2.2 1 1 1 2 2 2 2 Lipid II flippase MurJ DUF421 PF04239.12 EMT52762.1 - 1.3e-34 118.2 0.0 1.7e-33 114.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF421) DUF3397 PF11877.8 EMT52762.1 - 0.25 11.5 4.3 0.38 11.0 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) CorA PF01544.18 EMT52763.1 - 1.4e-63 214.9 4.2 1.7e-63 214.7 4.2 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Gram_pos_anchor PF00746.21 EMT52763.1 - 0.0063 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 LPXTG cell wall anchor motif DUF2207 PF09972.9 EMT52763.1 - 0.021 13.6 0.3 0.033 12.9 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3792 PF12670.7 EMT52764.1 - 5.9e-20 71.6 20.4 6.6e-20 71.4 20.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) YajC PF02699.15 EMT52765.1 - 1.3e-32 111.5 0.6 1.6e-32 111.2 0.6 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Orf78 PF06024.12 EMT52765.1 - 0.003 17.8 1.0 0.0076 16.5 0.1 1.9 2 0 0 2 2 2 1 Orf78 (ac78) WH2 PF02205.20 EMT52765.1 - 0.062 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 WH2 motif YMF19 PF02326.15 EMT52765.1 - 0.66 10.8 3.0 0.92 10.3 3.0 1.6 1 1 0 1 1 1 0 Plant ATP synthase F0 tRNA_anti-like PF12869.7 EMT52765.1 - 1.3 8.7 4.4 0.46 10.1 0.4 2.1 1 1 2 3 3 3 0 tRNA_anti-like TGT PF01702.18 EMT52766.1 - 3.5e-157 523.0 0.0 4e-157 522.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Longin PF13774.6 EMT52766.1 - 0.18 11.9 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 Regulated-SNARE-like domain Queuosine_synth PF02547.15 EMT52767.1 - 5.4e-145 482.5 0.0 6.2e-145 482.3 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein Lar_N PF09861.9 EMT52767.1 - 0.034 13.3 0.1 0.81 8.8 0.1 2.2 2 0 0 2 2 2 0 Lactate racemase N-terminal domain SpoIID PF08486.10 EMT52768.1 - 2.5e-24 85.7 0.0 7.8e-24 84.1 0.0 1.9 1 0 0 1 1 1 1 Stage II sporulation protein SPOR PF05036.13 EMT52768.1 - 3.4e-13 49.8 7.7 5.8e-08 33.0 4.1 2.8 1 1 1 2 2 2 2 Sporulation related domain SH3_3 PF08239.11 EMT52768.1 - 1.1e-06 28.8 0.5 0.00064 19.9 0.1 2.8 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_4 PF06347.13 EMT52768.1 - 0.0032 17.2 0.0 0.16 11.8 0.0 3.0 2 0 0 2 2 2 1 Bacterial SH3 domain DUF2905 PF11146.8 EMT52769.1 - 6.7e-26 90.3 4.7 7.5e-26 90.1 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2905) Ninjurin PF04923.12 EMT52769.1 - 0.021 14.8 0.1 0.021 14.8 0.1 1.6 2 0 0 2 2 2 0 Ninjurin DUF3094 PF11293.8 EMT52769.1 - 1.3 8.8 4.1 6.3 6.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) RuvB_N PF05496.12 EMT52770.1 - 5e-85 283.1 0.0 7.3e-85 282.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 EMT52770.1 - 4.7e-33 112.8 1.1 9.8e-33 111.7 1.1 1.6 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 EMT52770.1 - 6.2e-26 90.1 0.0 1.1e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 EMT52770.1 - 2.4e-20 73.3 0.0 6.1e-20 72.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMT52770.1 - 5.9e-11 42.5 0.1 2.7e-09 37.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EMT52770.1 - 1.9e-06 27.3 0.0 5.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EMT52770.1 - 3.6e-06 26.5 0.2 0.014 14.7 0.0 2.7 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EMT52770.1 - 0.0003 20.8 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EMT52770.1 - 0.00031 20.5 0.0 0.74 9.5 0.0 2.2 1 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EMT52770.1 - 0.00034 20.9 0.3 0.1 12.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EMT52770.1 - 0.00045 20.6 0.7 0.022 15.2 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain NTPase_1 PF03266.15 EMT52770.1 - 0.0012 18.8 0.3 0.06 13.3 0.0 2.4 1 1 1 2 2 2 1 NTPase Rad17 PF03215.15 EMT52770.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 EMT52770.1 - 0.0016 18.5 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EMT52770.1 - 0.0019 18.5 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.11 EMT52770.1 - 0.0021 17.9 0.0 0.031 14.1 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 EMT52770.1 - 0.0034 17.3 0.1 0.084 12.7 0.0 2.4 3 0 0 3 3 3 1 Bacterial dnaA protein NB-ARC PF00931.22 EMT52770.1 - 0.0041 16.3 0.0 0.023 13.9 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain Resolvase PF00239.21 EMT52770.1 - 0.0043 17.2 0.0 0.024 14.7 0.0 2.2 2 1 1 3 3 3 1 Resolvase, N terminal domain Sigma54_activ_2 PF14532.6 EMT52770.1 - 0.0044 17.2 0.0 0.0071 16.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain MCM PF00493.23 EMT52770.1 - 0.0047 16.1 0.0 0.38 9.8 0.0 2.3 1 1 0 1 1 1 1 MCM P-loop domain AAA_18 PF13238.6 EMT52770.1 - 0.0054 17.3 0.0 0.015 15.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain ResIII PF04851.15 EMT52770.1 - 0.0054 16.7 0.0 2.7 8.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TniB PF05621.11 EMT52770.1 - 0.013 14.9 0.1 0.27 10.6 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 EMT52770.1 - 0.033 13.3 0.0 0.21 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 EMT52770.1 - 0.037 13.7 0.1 0.1 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMT52770.1 - 0.039 14.1 0.0 0.094 12.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 EMT52770.1 - 0.064 13.7 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMT52770.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain HTH_15 PF12324.8 EMT52770.1 - 0.082 12.9 0.1 4.8 7.2 0.0 2.6 3 0 0 3 3 2 0 Helix-turn-helix domain of alkylmercury lyase IstB_IS21 PF01695.17 EMT52770.1 - 0.088 12.5 0.1 0.6 9.8 0.1 2.2 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 EMT52770.1 - 0.089 13.1 0.3 1.9 8.8 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EMT52770.1 - 0.14 12.2 0.0 4 7.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 EMT52770.1 - 0.16 12.2 0.3 0.51 10.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EMT52770.1 - 0.18 10.4 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain RuvA_N PF01330.21 EMT52771.1 - 8.3e-21 73.9 0.7 3.7e-20 71.8 0.0 2.4 4 0 0 4 4 4 1 RuvA N terminal domain HHH_5 PF14520.6 EMT52771.1 - 2.4e-17 63.3 0.8 4.3e-17 62.5 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain RuvA_C PF07499.13 EMT52771.1 - 2.8e-11 43.7 1.6 5.2e-11 42.8 1.6 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain IMS_HHH PF11798.8 EMT52771.1 - 0.00038 20.6 0.3 0.0034 17.6 0.0 2.6 3 0 0 3 3 3 1 IMS family HHH motif HHH PF00633.23 EMT52771.1 - 0.00048 19.9 0.5 0.26 11.2 0.0 2.9 2 1 0 2 2 2 2 Helix-hairpin-helix motif HHH_8 PF14716.6 EMT52771.1 - 0.00094 19.5 0.9 0.23 11.8 0.0 3.2 2 1 1 3 3 3 1 Helix-hairpin-helix domain HHH_3 PF12836.7 EMT52771.1 - 0.031 14.5 0.0 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Tic110 PF16940.5 EMT52771.1 - 0.048 12.1 0.1 0.061 11.8 0.1 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Transposase_20 PF02371.16 EMT52771.1 - 0.1 12.9 0.2 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family HHH_2 PF12826.7 EMT52771.1 - 0.12 12.5 0.2 36 4.6 0.0 3.0 2 1 1 3 3 3 0 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 EMT52771.1 - 0.25 12.0 2.6 2.4 8.8 0.6 2.9 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold RuvC PF02075.17 EMT52772.1 - 1.4e-54 184.0 0.1 1.6e-54 183.8 0.1 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC DUF460 PF04312.13 EMT52772.1 - 0.041 13.6 0.2 0.071 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) LPD11 PF18824.1 EMT52772.1 - 0.14 12.2 0.1 0.41 10.8 0.0 1.7 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 Col_cuticle_N PF01484.17 EMT52773.1 - 0.24 11.5 1.6 0.42 10.7 1.6 1.4 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain BofC_C PF08955.10 EMT52775.1 - 2.1e-28 98.1 0.0 3.5e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 BofC C-terminal domain 5_nucleotid_C PF02872.18 EMT52776.1 - 1.7e-20 73.8 0.2 3.3e-20 72.9 0.2 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EMT52776.1 - 1e-12 49.0 0.9 2e-12 48.1 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase APH PF01636.23 EMT52777.1 - 1.9e-11 44.3 0.1 2.7e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EMT52777.1 - 0.0088 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Bul1_C PF04426.12 EMT52777.1 - 0.24 10.8 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus LysM PF01476.20 EMT52778.1 - 3e-15 56.0 0.0 4.3e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 LysM domain PDT PF00800.18 EMT52779.1 - 2.5e-57 193.7 0.0 3e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EMT52779.1 - 1.6e-07 31.0 0.0 3.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain GHMP_kinases_C PF08544.13 EMT52780.1 - 2.3e-11 43.9 0.1 5.6e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EMT52780.1 - 1.6e-08 34.6 2.6 1.7e-08 34.6 0.4 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain PALP PF00291.25 EMT52781.1 - 7.9e-81 271.7 2.2 9.2e-81 271.5 2.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF5133 PF17196.4 EMT52781.1 - 0.058 13.6 1.7 0.67 10.2 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) Homoserine_dh PF00742.19 EMT52782.1 - 2.2e-67 226.3 0.1 6.4e-67 224.8 0.1 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EMT52782.1 - 2.7e-21 76.4 0.4 7.6e-21 74.9 0.4 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 EMT52782.1 - 4.4e-08 32.7 0.3 1.5e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 ACT domain GFO_IDH_MocA PF01408.22 EMT52782.1 - 6.4e-05 23.8 0.1 0.00026 21.8 0.1 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EMT52782.1 - 0.0016 18.7 0.4 0.0046 17.2 0.4 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ACT_4 PF13291.6 EMT52782.1 - 0.0019 18.7 0.5 0.0071 16.9 0.1 2.1 2 0 0 2 2 2 1 ACT domain ADH_zinc_N_2 PF13602.6 EMT52782.1 - 0.04 15.0 0.5 1.5 9.9 0.0 2.6 2 1 0 2 2 2 0 Zinc-binding dehydrogenase ACT PF01842.25 EMT52783.1 - 1.7e-06 27.7 0.0 2.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 EMT52783.1 - 0.0036 17.9 0.1 0.0067 17.0 0.1 1.4 1 0 0 1 1 1 1 ACT domain HTH_29 PF13551.6 EMT52783.1 - 0.0049 16.9 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.15 EMT52783.1 - 0.005 16.9 0.0 0.0098 15.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase ACT_6 PF13740.6 EMT52783.1 - 0.069 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 ACT domain HTH_28 PF13518.6 EMT52783.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PilZ PF07238.14 EMT52784.1 - 0.00045 20.5 0.1 0.019 15.3 0.0 2.8 1 1 2 3 3 3 1 PilZ domain TOBE_2 PF08402.10 EMT52784.1 - 0.0061 16.7 0.1 0.017 15.3 0.1 1.8 2 0 0 2 2 2 1 TOBE domain GTP1_OBG PF01018.22 EMT52785.1 - 1.1e-59 200.5 6.2 1.5e-59 200.0 6.2 1.2 1 0 0 1 1 1 1 GTP1/OBG DUF1967 PF09269.11 EMT52785.1 - 4.5e-28 97.0 3.4 7.7e-28 96.2 1.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1967) MMR_HSR1 PF01926.23 EMT52785.1 - 5.4e-24 84.5 0.0 1e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMT52785.1 - 1.2e-11 44.4 0.1 6e-11 42.1 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 EMT52785.1 - 0.001 18.5 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 EMT52785.1 - 0.0017 18.2 0.2 0.11 12.3 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1_C PF08438.10 EMT52785.1 - 0.0024 18.4 0.1 0.0058 17.2 0.1 1.7 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MeaB PF03308.16 EMT52785.1 - 0.0032 16.5 1.3 0.55 9.2 0.1 2.8 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EMT52785.1 - 0.0033 17.3 0.4 0.42 10.5 0.1 2.7 2 1 1 3 3 3 1 RsgA GTPase Ras PF00071.22 EMT52785.1 - 0.0051 16.4 0.1 0.4 10.3 0.0 2.5 2 0 0 2 2 2 1 Ras family SPOB_a PF14689.6 EMT52786.1 - 9.8e-21 73.2 0.2 1.6e-20 72.6 0.2 1.3 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain SPOB_ab PF14682.6 EMT52786.1 - 4.7e-15 55.6 0.1 8.4e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 Sporulation initiation phospho-transferase B, C-terminal TPR_14 PF13428.6 EMT52786.1 - 0.11 13.4 0.1 0.47 11.4 0.1 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Ribosomal_L27 PF01016.19 EMT52787.1 - 1.6e-34 117.8 3.5 1.8e-34 117.6 3.5 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Biotin_lipoyl_2 PF13533.6 EMT52787.1 - 0.1 12.4 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like Peptidase_Prp PF04327.12 EMT52788.1 - 7.2e-21 74.2 0.0 8.3e-21 74.0 0.0 1.0 1 0 0 1 1 1 1 Cysteine protease Prp Ribosomal_L21p PF00829.21 EMT52789.1 - 2.1e-42 143.4 6.0 2.4e-42 143.3 6.0 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein RNase_E_G PF10150.9 EMT52790.1 - 5.3e-88 295.0 0.0 6.9e-88 294.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 EMT52790.1 - 0.037 14.4 0.1 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 S1 RNA binding domain RF-1 PF00472.20 EMT52790.1 - 0.14 12.1 0.4 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 RF-1 domain Acetyltransf_8 PF13523.6 EMT52791.1 - 3e-27 95.1 0.0 4.2e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT52791.1 - 9.2e-16 58.1 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EMT52791.1 - 1.6e-14 54.8 0.0 2.1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT52791.1 - 2.1e-06 27.6 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EMT52791.1 - 6e-06 26.6 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT52791.1 - 0.00048 20.1 0.0 0.00066 19.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT52791.1 - 0.016 15.4 0.0 2.8 8.1 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_M50 PF02163.22 EMT52792.1 - 1e-14 54.4 9.1 4.5e-08 32.7 1.9 2.8 1 1 2 3 3 3 2 Peptidase family M50 Peptidase_M50B PF13398.6 EMT52792.1 - 0.0015 18.2 4.6 0.0015 18.2 4.6 2.3 1 1 1 2 2 2 1 Peptidase M50B-like Peptidase_M23 PF01551.22 EMT52793.1 - 5e-09 36.3 0.2 7.3e-09 35.7 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M23 CSD PF00313.22 EMT52794.1 - 1.3e-31 108.2 1.6 1.5e-31 108.1 1.6 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EMT52794.1 - 0.0016 18.1 0.4 0.0023 17.6 0.4 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain Rho_RNA_bind PF07497.12 EMT52794.1 - 0.096 12.6 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain CusF_Ec PF11604.8 EMT52794.1 - 0.097 12.6 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF FTSW_RODA_SPOVE PF01098.19 EMT52795.1 - 8.4e-86 288.2 26.8 1e-85 287.9 26.8 1.0 1 0 0 1 1 1 1 Cell cycle protein AAA_31 PF13614.6 EMT52796.1 - 3.7e-25 88.9 0.1 7.7e-25 87.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EMT52796.1 - 2e-24 86.1 0.2 2.8e-24 85.6 0.2 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EMT52796.1 - 4.5e-22 78.7 2.0 1e-21 77.5 2.0 1.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 EMT52796.1 - 4.7e-14 52.3 0.2 7.2e-14 51.7 0.2 1.3 1 0 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 EMT52796.1 - 1.7e-12 47.3 0.3 5.2e-12 45.8 0.3 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 EMT52796.1 - 2.3e-10 40.2 4.5 5.2e-07 29.1 2.0 2.9 2 1 1 3 3 3 2 Anion-transporting ATPase Fer4_NifH PF00142.18 EMT52796.1 - 2.4e-09 37.1 2.1 4.3e-05 23.1 0.2 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 EMT52796.1 - 0.0001 22.1 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EMT52796.1 - 0.0034 17.2 0.2 0.01 15.6 0.1 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 EMT52796.1 - 0.012 15.3 3.6 0.028 14.0 1.5 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain VirC1 PF07015.11 EMT52796.1 - 0.029 13.7 0.5 0.11 11.8 0.4 1.9 2 0 0 2 2 2 0 VirC1 protein AAA_33 PF13671.6 EMT52796.1 - 0.033 14.4 0.1 0.066 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMT52796.1 - 0.037 13.6 2.4 0.19 11.3 2.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_26 PF13500.6 EMT52796.1 - 0.057 13.2 7.7 0.23 11.2 0.6 2.7 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EMT52796.1 - 0.12 12.2 0.8 0.92 9.2 0.8 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EMT52796.1 - 0.22 11.4 1.6 6.4 6.7 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase MinC_C PF03775.16 EMT52797.1 - 2e-30 104.8 0.1 5.9e-30 103.3 0.0 1.8 2 0 0 2 2 2 1 Septum formation inhibitor MinC, C-terminal domain FapA PF03961.13 EMT52797.1 - 7.4e-05 21.5 0.2 0.003 16.2 0.0 2.2 1 1 1 2 2 2 2 Flagellar Assembly Protein A Transpeptidase PF00905.22 EMT52798.1 - 5e-67 226.3 0.2 7.1e-67 225.8 0.2 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 EMT52798.1 - 5.5e-41 140.9 0.2 1.1e-40 139.9 0.2 1.4 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain MreD PF04093.12 EMT52799.1 - 1.2e-13 51.5 22.0 1.4e-13 51.2 22.0 1.1 1 0 0 1 1 1 1 rod shape-determining protein MreD MreC PF04085.14 EMT52800.1 - 3.1e-43 147.3 0.8 4.3e-43 146.8 0.8 1.2 1 0 0 1 1 1 1 rod shape-determining protein MreC DUF3053 PF11254.8 EMT52800.1 - 0.0047 16.6 0.0 0.0075 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3053) YajC PF02699.15 EMT52800.1 - 0.033 14.1 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 Preprotein translocase subunit MreB_Mbl PF06723.13 EMT52801.1 - 1.9e-151 503.5 10.4 2.2e-151 503.3 10.4 1.0 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 EMT52801.1 - 4.6e-11 43.0 1.7 1.6e-10 41.3 0.1 2.5 2 2 0 2 2 2 1 Cell division protein FtsA Actin PF00022.19 EMT52801.1 - 1.2e-10 40.6 0.2 1e-06 27.7 0.1 2.1 2 0 0 2 2 2 2 Actin HSP70 PF00012.20 EMT52801.1 - 1e-09 37.2 7.4 2.9e-09 35.7 1.7 2.7 1 1 1 2 2 2 2 Hsp70 protein PilM_2 PF11104.8 EMT52801.1 - 2.2e-05 23.7 0.1 0.03 13.4 0.0 2.4 2 1 0 2 2 2 2 Type IV pilus assembly protein PilM; EutA PF06277.11 EMT52801.1 - 0.0016 17.4 1.5 0.0019 17.1 0.1 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutA DDR PF08841.10 EMT52801.1 - 0.0029 16.6 2.7 0.0041 16.1 1.0 1.9 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 EMT52801.1 - 0.014 15.2 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain RadC PF04002.15 EMT52802.1 - 2.6e-47 159.8 0.0 3.8e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 RadC-like JAB domain HHH_2 PF12826.7 EMT52802.1 - 1.4e-05 25.1 0.1 2.4e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EMT52802.1 - 0.00075 20.1 0.1 0.0014 19.2 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Prok-JAB PF14464.6 EMT52802.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain HHH PF00633.23 EMT52802.1 - 0.022 14.6 0.1 0.07 13.0 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Maf PF02545.14 EMT52803.1 - 9.2e-62 207.8 0.1 1e-61 207.6 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein DUF4321 PF14209.6 EMT52804.1 - 1.7e-14 53.3 0.2 3.8e-14 52.2 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4321) ACP_syn_III_C PF08541.10 EMT52806.1 - 4.9e-32 110.0 0.0 1.4e-31 108.5 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EMT52806.1 - 1.4e-29 101.7 0.9 2.3e-29 101.1 0.9 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EMT52806.1 - 4.1e-07 29.6 0.1 7.4e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Chal_sti_synt_N PF00195.19 EMT52806.1 - 4.6e-06 26.2 0.4 8e-05 22.2 0.2 2.1 1 1 1 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 EMT52806.1 - 3.7e-05 23.2 0.0 5.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.15 EMT52806.1 - 0.0067 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain HMG_CoA_synt_N PF01154.17 EMT52806.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal Mur_ligase PF01225.25 EMT52807.1 - 1.9e-28 98.6 0.4 8e-28 96.6 0.4 2.2 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 EMT52807.1 - 1.5e-25 90.4 0.0 2.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EMT52807.1 - 8.9e-22 77.2 0.1 1.3e-20 73.4 0.1 2.5 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain DELLA PF12041.8 EMT52807.1 - 0.092 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal Mur_ligase_M PF08245.12 EMT52808.1 - 2e-13 50.8 0.0 2.7e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EMT52808.1 - 2.2e-06 27.8 0.0 1.4e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain tRNA-synt_1 PF00133.22 EMT52809.1 - 7.6e-225 747.7 0.8 3.3e-223 742.3 0.8 2.7 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMT52809.1 - 5.6e-45 153.0 0.1 1.3e-44 151.8 0.1 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EMT52809.1 - 1.4e-30 106.4 5.3 1.1e-11 44.1 0.0 4.8 3 2 2 5 5 5 4 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 EMT52809.1 - 1.1e-24 86.5 6.3 2.4e-24 85.4 6.3 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 EMT52809.1 - 4.1e-12 46.0 0.0 3.7e-09 36.4 0.0 2.3 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EMT52809.1 - 4.7e-06 26.2 0.0 0.0052 16.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain ABC_tran_CTD PF16326.5 EMT52809.1 - 0.00063 19.9 2.4 0.0017 18.6 2.4 1.7 1 0 0 1 1 1 1 ABC transporter C-terminal domain tRNA-synt_1f PF01921.18 EMT52809.1 - 0.012 14.6 0.0 0.033 13.1 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) TolA_bind_tri PF16331.5 EMT52809.1 - 0.019 15.1 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation HypA PF01155.19 EMT52809.1 - 0.021 14.9 0.5 0.044 13.8 0.5 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EMT52809.1 - 0.073 13.1 0.8 0.14 12.2 0.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon CCDC144C PF14915.6 EMT52809.1 - 0.1 11.7 0.5 0.16 11.0 0.5 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Zn-ribbon_8 PF09723.10 EMT52809.1 - 0.11 12.6 1.6 0.23 11.6 1.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain FliJ PF02050.16 EMT52809.1 - 0.16 12.2 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein CCDC-167 PF15188.6 EMT52809.1 - 0.17 12.3 4.9 0.079 13.3 2.3 1.8 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 tRNA-synt_1b PF00579.25 EMT52809.1 - 0.2 10.9 2.2 5.1 6.3 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) DUF4164 PF13747.6 EMT52809.1 - 0.34 11.2 1.2 1.2 9.5 1.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) zinc_ribbon_2 PF13240.6 EMT52809.1 - 0.53 10.1 2.0 1.1 9.1 2.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain STAS PF01740.21 EMT52810.1 - 7.7e-09 35.2 0.1 9.2e-09 35.0 0.1 1.1 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EMT52810.1 - 8.1e-09 35.7 0.0 9.3e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 STAS domain HATPase_c_2 PF13581.6 EMT52811.1 - 5.2e-12 45.8 0.0 1.2e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 EMT52811.1 - 0.00029 21.3 0.0 0.00084 19.8 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMT52811.1 - 0.0083 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2326 PF10088.9 EMT52811.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) SpoIIE PF07228.12 EMT52812.1 - 1.2e-37 129.8 0.0 2.9e-37 128.5 0.0 1.7 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) S_2TMBeta PF18153.1 EMT52812.1 - 0.016 15.0 0.6 0.037 13.8 0.6 1.5 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain LysM PF01476.20 EMT52816.1 - 3.6e-09 36.5 0.0 6.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain Amino_oxidase PF01593.24 EMT52817.1 - 3.7e-61 207.8 0.0 4.4e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMT52817.1 - 3.3e-13 49.7 0.0 7.6e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMT52817.1 - 1.4e-10 41.3 0.7 5.9e-06 26.1 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMT52817.1 - 1e-07 32.1 0.0 0.0041 17.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EMT52817.1 - 7.7e-05 22.1 0.0 0.044 13.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EMT52817.1 - 0.0028 16.5 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 MCRA family Thi4 PF01946.17 EMT52817.1 - 0.0076 15.5 0.0 0.029 13.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EMT52817.1 - 0.0078 16.7 0.0 0.1 13.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMT52817.1 - 0.047 12.6 0.0 0.087 11.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EMT52817.1 - 0.17 11.1 0.0 18 4.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT52817.1 - 0.18 10.5 0.0 8.8 4.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 EMT52817.1 - 0.27 10.5 0.8 0.82 8.8 0.2 2.0 2 1 0 2 2 2 0 FAD binding domain Ferrochelatase PF00762.19 EMT52818.1 - 1.4e-79 267.5 0.0 1.6e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase URO-D PF01208.17 EMT52819.1 - 5.8e-126 420.3 0.0 6.6e-126 420.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF4097 PF13349.6 EMT52820.1 - 4.7e-28 98.2 13.4 9.2e-20 71.0 5.0 1.6 1 1 1 2 2 2 2 Putative adhesin TamB PF04357.13 EMT52820.1 - 0.01 15.1 4.1 0.031 13.5 1.0 2.1 1 1 1 2 2 2 0 TamB, inner membrane protein subunit of TAM complex DUF1700 PF08006.11 EMT52821.1 - 3.4e-51 173.4 0.0 3.8e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) PadR PF03551.14 EMT52822.1 - 4e-20 71.6 0.2 4.9e-20 71.3 0.2 1.1 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 EMT52822.1 - 0.0023 18.1 0.0 0.0026 17.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 EMT52822.1 - 0.0095 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix TrmB PF01978.19 EMT52822.1 - 0.031 14.1 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 EMT52822.1 - 0.054 13.6 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Mrr_N PF14338.6 EMT52822.1 - 0.085 13.0 0.0 0.32 11.2 0.0 2.0 1 1 0 1 1 1 0 Mrr N-terminal domain PaaX PF07848.12 EMT52822.1 - 0.087 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein Penicillinase_R PF03965.16 EMT52822.1 - 0.15 12.4 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor HTH_IclR PF09339.10 EMT52822.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain 5_nucleotid_C PF02872.18 EMT52823.1 - 2.6e-52 177.2 0.1 6.5e-52 175.9 0.0 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EMT52823.1 - 2e-16 61.1 1.9 3.5e-16 60.3 1.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 EMT52823.1 - 4.9e-05 22.9 0.1 0.00016 21.2 0.1 1.8 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap SLH PF00395.20 EMT52823.1 - 0.00073 19.5 0.0 2 8.5 0.1 3.0 3 0 0 3 3 3 2 S-layer homology domain Flavodoxin_4 PF12682.7 EMT52823.1 - 0.073 12.8 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Flavodoxin Abhydrolase_1 PF00561.20 EMT52824.1 - 2.2e-30 106.2 0.0 8.2e-29 101.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMT52824.1 - 4.2e-23 83.1 0.0 5.1e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMT52824.1 - 4.6e-23 81.7 0.0 6e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EMT52824.1 - 1.5e-11 43.5 0.0 1.9e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 EMT52824.1 - 3.6e-08 33.8 0.0 1.2e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 EMT52824.1 - 3.1e-05 23.8 0.0 0.00068 19.4 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EMT52824.1 - 6.9e-05 22.8 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase BAAT_C PF08840.11 EMT52824.1 - 0.00019 21.4 0.0 0.00041 20.3 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 EMT52824.1 - 0.00039 20.2 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EMT52824.1 - 0.0012 18.4 0.0 0.4 10.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family PGAP1 PF07819.13 EMT52824.1 - 0.0026 17.5 0.0 0.048 13.4 0.0 2.3 1 1 1 2 2 2 1 PGAP1-like protein DLH PF01738.18 EMT52824.1 - 0.0034 17.0 0.0 0.42 10.1 0.0 2.5 1 1 2 3 3 3 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 EMT52824.1 - 0.0066 16.0 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase UPF0227 PF05728.12 EMT52824.1 - 0.008 16.1 0.0 0.063 13.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Chlorophyllase PF07224.11 EMT52824.1 - 0.012 14.7 0.0 0.03 13.3 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase DUF676 PF05057.14 EMT52824.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 EMT52824.1 - 0.042 12.8 0.0 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme Lipase_3 PF01764.25 EMT52824.1 - 0.06 13.2 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 EMT52824.1 - 0.062 12.6 0.0 0.37 10.1 0.0 2.1 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 EMT52824.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.4 2 0 0 2 2 2 0 Palmitoyl protein thioesterase DUF1057 PF06342.12 EMT52824.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 EMT52825.1 - 0.0028 17.0 0.2 0.031 13.5 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EMT52825.1 - 0.027 14.0 0.2 1.2 8.6 0.1 2.1 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase DLH PF01738.18 EMT52825.1 - 0.16 11.5 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family GyrI-like PF06445.15 EMT52826.1 - 9.1e-23 81.3 0.0 1.2e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 EMT52826.1 - 5.3e-20 72.1 0.0 6.9e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Integron-associated effector binding protein DUF493 PF04359.14 EMT52827.1 - 0.099 13.2 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF493) Aminotran_1_2 PF00155.21 EMT52828.1 - 2.9e-35 122.1 0.0 4.5e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EMT52828.1 - 2.1e-14 52.9 0.0 8.2e-14 51.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 EMT52828.1 - 5.2e-09 35.4 0.0 1.6e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 EMT52828.1 - 0.003 16.9 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family HTH_41 PF14502.6 EMT52828.1 - 0.092 12.5 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain EamA PF00892.20 EMT52829.1 - 2e-34 118.7 39.2 3.7e-17 62.8 16.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EMT52829.1 - 1.6e-05 24.4 11.3 2e-05 24.1 11.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Aminotran_3 PF00202.21 EMT52830.1 - 7.9e-83 278.4 0.0 9.2e-83 278.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMT52830.1 - 1.1e-05 24.8 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II ALAD PF00490.21 EMT52831.1 - 2.5e-149 496.7 0.1 2.8e-149 496.6 0.1 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase YAcAr PF10686.9 EMT52831.1 - 0.15 12.0 0.1 1 9.4 0.0 2.4 3 0 0 3 3 3 0 YspA, cpYpsA-related SLOG family HEM4 PF02602.15 EMT52832.1 - 4.2e-67 225.9 0.0 4.8e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Toxin_trans PF07952.12 EMT52832.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Porphobil_deam PF01379.20 EMT52833.1 - 6.2e-84 280.6 0.0 7.9e-84 280.2 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EMT52833.1 - 1.5e-19 70.1 0.0 2.8e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Cytochrom_C_asm PF01578.20 EMT52834.1 - 1.3e-28 100.2 18.5 1.3e-28 100.2 18.5 1.6 2 0 0 2 2 2 1 Cytochrome C assembly protein GlutR_N PF05201.15 EMT52835.1 - 8.9e-50 168.2 0.2 1.6e-49 167.4 0.2 1.4 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 EMT52835.1 - 5.4e-46 156.1 0.0 1.1e-45 155.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 EMT52835.1 - 2.7e-22 79.0 0.1 1.5e-21 76.7 0.0 2.2 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 EMT52835.1 - 4.2e-06 27.3 0.0 1.1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EMT52835.1 - 0.00027 21.2 0.0 0.00063 20.0 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EMT52835.1 - 0.00085 18.7 0.2 0.0017 17.8 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HTH_10 PF04967.12 EMT52835.1 - 0.0012 18.6 0.9 0.045 13.6 0.0 3.6 4 0 0 4 4 4 1 HTH DNA binding domain NAD_binding_10 PF13460.6 EMT52835.1 - 0.0021 17.9 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DBD_HTH PF18430.1 EMT52835.1 - 0.0097 15.7 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 1 Putative DNA-binding domain OCD_Mu_crystall PF02423.15 EMT52835.1 - 0.016 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_7 PF13241.6 EMT52835.1 - 0.024 15.1 0.0 0.057 13.9 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 EMT52835.1 - 0.044 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CvfB_WH PF17783.1 EMT52835.1 - 0.05 13.4 0.0 9.6 6.1 0.0 2.7 2 0 0 2 2 2 0 CvfB-like winged helix domain GFO_IDH_MocA PF01408.22 EMT52835.1 - 0.057 14.2 0.0 0.2 12.5 0.0 2.0 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Staph_opine_DH PF10100.9 EMT52835.1 - 0.061 12.0 0.1 0.1 11.2 0.1 1.3 1 0 0 1 1 1 0 Staphylopine dehydrogenase EamA PF00892.20 EMT52836.1 - 9.7e-36 123.0 46.7 6.3e-18 65.3 23.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 EMT52836.1 - 3.9 7.5 8.8 3 7.9 0.5 3.3 2 1 0 2 2 2 0 Putative transmembrane family 234 AC_N PF16214.5 EMT52836.1 - 8.8 5.3 7.5 12 4.9 7.5 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region NAGidase PF07555.13 EMT52837.1 - 2e-92 309.6 0.0 2.7e-92 309.2 0.0 1.2 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase MMR_HSR1 PF01926.23 EMT52838.1 - 4.3e-23 81.6 0.0 8e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMT52838.1 - 2.8e-08 33.4 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EMT52838.1 - 1.6e-07 31.5 0.9 0.019 15.0 0.1 2.9 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EMT52838.1 - 2.3e-06 27.6 0.0 0.00041 20.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EMT52838.1 - 0.0002 20.8 0.1 0.0004 19.9 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EMT52838.1 - 0.00092 19.4 0.5 0.0038 17.5 0.5 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EMT52838.1 - 0.018 14.4 0.1 0.067 12.6 0.1 1.9 2 1 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 EMT52838.1 - 0.031 14.0 0.1 0.3 10.8 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EMT52838.1 - 0.033 14.4 0.1 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2239 PF09998.9 EMT52838.1 - 0.049 13.4 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) AIG1 PF04548.16 EMT52838.1 - 0.067 12.5 0.1 0.12 11.7 0.1 1.6 1 1 0 1 1 1 0 AIG1 family Lon_C PF05362.13 EMT52839.1 - 1.5e-102 341.5 0.5 3.3e-102 340.3 0.4 1.7 2 0 0 2 2 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EMT52839.1 - 6.7e-44 150.3 3.4 1.4e-43 149.2 3.4 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EMT52839.1 - 9.4e-24 84.3 0.2 5.4e-23 81.9 0.0 2.4 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EMT52839.1 - 1.4e-10 41.0 0.0 2.5e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EMT52839.1 - 7e-10 39.1 0.5 2.8e-09 37.1 0.0 2.4 3 0 0 3 3 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMT52839.1 - 4.6e-07 30.4 0.6 4.3e-06 27.2 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EMT52839.1 - 2.7e-06 27.6 0.0 1.5e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 EMT52839.1 - 3.2e-06 26.3 0.0 5.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain NACHT PF05729.12 EMT52839.1 - 1.8e-05 24.7 0.1 0.014 15.3 0.0 4.1 4 0 0 4 4 4 1 NACHT domain AAA_22 PF13401.6 EMT52839.1 - 2.2e-05 24.7 0.0 0.00044 20.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMT52839.1 - 0.00044 20.8 0.3 0.016 15.7 0.0 3.3 3 1 0 4 4 3 1 AAA domain AAA_3 PF07726.11 EMT52839.1 - 0.00081 19.3 0.0 0.0025 17.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EMT52839.1 - 0.0011 18.7 0.0 0.0035 17.1 0.0 1.9 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EMT52839.1 - 0.0017 18.5 0.0 0.0042 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EMT52839.1 - 0.0025 17.6 0.0 0.01 15.6 0.0 2.1 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EMT52839.1 - 0.0026 17.7 0.0 0.0071 16.3 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 EMT52839.1 - 0.0032 16.7 0.0 0.024 13.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 EMT52839.1 - 0.0038 17.2 0.0 0.0099 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EMT52839.1 - 0.0042 17.1 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EMT52839.1 - 0.0043 17.4 0.0 0.013 15.8 0.0 2.0 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 EMT52839.1 - 0.0065 17.0 2.9 0.087 13.3 0.0 3.2 2 1 0 2 2 2 1 ABC transporter NTPase_1 PF03266.15 EMT52839.1 - 0.01 15.8 0.2 0.067 13.1 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 EMT52839.1 - 0.011 15.5 0.0 0.091 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EMT52839.1 - 0.013 14.7 0.0 0.17 11.0 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.13 EMT52839.1 - 0.016 14.4 2.0 0.23 10.6 0.0 2.8 3 0 0 3 3 3 0 TIP49 P-loop domain AAA_24 PF13479.6 EMT52839.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MIEAP PF16026.5 EMT52839.1 - 0.048 13.9 0.2 0.13 12.4 0.2 1.8 1 0 0 1 1 1 0 Mitochondria-eating protein Sigma54_activat PF00158.26 EMT52839.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EMT52839.1 - 0.064 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 EMT52839.1 - 0.084 13.0 0.1 0.54 10.3 0.1 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 EMT52839.1 - 0.094 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.25 EMT52839.1 - 0.1 12.2 0.0 0.53 9.9 0.0 2.2 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 EMT52839.1 - 0.11 12.9 0.1 0.44 10.9 0.0 2.2 3 0 0 3 3 1 0 AAA domain AAA_7 PF12775.7 EMT52839.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 EMT52839.1 - 0.45 10.9 0.0 0.45 10.9 0.0 3.3 4 1 1 5 5 2 0 AAA domain AAA_23 PF13476.6 EMT52839.1 - 2.1 8.8 0.0 2.1 8.8 0.0 2.8 2 2 0 2 2 1 0 AAA domain Lon_C PF05362.13 EMT52840.1 - 9.1e-31 107.0 2.0 2.3e-30 105.7 2.0 1.7 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EMT52840.1 - 9.3e-17 61.7 0.0 1.7e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EMT52840.1 - 8.2e-16 58.0 0.1 1.9e-15 56.8 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EMT52840.1 - 5.7e-13 48.9 0.0 2.7e-12 46.7 0.0 2.0 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 EMT52840.1 - 2.3e-10 40.6 0.0 1.2e-08 35.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMT52840.1 - 5.1e-09 36.1 0.1 5e-05 23.1 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain ChlI PF13541.6 EMT52840.1 - 5.8e-09 35.8 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EMT52840.1 - 4.8e-07 30.3 0.0 8.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_32 PF13654.6 EMT52840.1 - 1.8e-06 27.0 0.0 0.003 16.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EMT52840.1 - 6e-05 23.3 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EMT52840.1 - 0.00012 22.3 0.1 0.0014 18.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 EMT52840.1 - 0.0046 16.7 0.0 0.021 14.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EMT52840.1 - 0.0062 16.5 0.0 0.019 14.9 0.0 1.7 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EMT52840.1 - 0.01 16.2 0.0 0.38 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 EMT52840.1 - 0.012 14.8 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain Sigma54_activ_2 PF14532.6 EMT52840.1 - 0.014 15.5 0.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EMT52840.1 - 0.031 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EMT52840.1 - 0.037 14.0 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 EMT52840.1 - 0.046 13.6 0.0 0.079 12.9 0.0 1.5 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 EMT52840.1 - 0.056 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EMT52840.1 - 0.11 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 EMT52840.1 - 0.13 12.7 0.0 0.37 11.2 0.0 1.7 2 0 0 2 2 1 0 RNA helicase DNA_pol3_delta2 PF13177.6 EMT52840.1 - 0.24 11.1 0.4 43 3.8 0.0 3.3 4 0 0 4 4 4 0 DNA polymerase III, delta subunit AAA_2 PF07724.14 EMT52841.1 - 9.6e-51 172.3 0.0 2e-50 171.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 EMT52841.1 - 3.2e-20 71.7 4.9 3.2e-20 71.7 4.9 1.8 2 0 0 2 2 1 1 ClpX C4-type zinc finger ClpB_D2-small PF10431.9 EMT52841.1 - 6.5e-18 64.6 0.4 1.7e-17 63.3 0.4 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EMT52841.1 - 3e-16 60.1 0.1 9.5e-16 58.4 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMT52841.1 - 1.9e-07 31.2 0.0 1.9e-06 27.9 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMT52841.1 - 5.6e-06 26.7 0.2 5.2e-05 23.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EMT52841.1 - 5.8e-06 26.1 0.2 1.6e-05 24.7 0.2 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EMT52841.1 - 6.2e-06 25.8 0.0 0.00053 19.4 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI MCM PF00493.23 EMT52841.1 - 2.4e-05 23.5 0.1 4.2e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 EMT52841.1 - 3.7e-05 23.5 0.0 0.016 14.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT52841.1 - 0.00039 20.6 0.0 0.0011 19.1 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EMT52841.1 - 0.00074 19.9 0.2 0.0036 17.7 0.0 2.0 2 1 1 3 3 2 1 AAA ATPase domain T2SSE PF00437.20 EMT52841.1 - 0.0012 17.9 0.1 0.0026 16.9 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 EMT52841.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 EMT52841.1 - 0.0027 17.8 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMT52841.1 - 0.0031 18.1 0.0 0.0085 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EMT52841.1 - 0.0038 17.2 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EMT52841.1 - 0.0049 16.6 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EMT52841.1 - 0.014 14.6 0.1 0.037 13.2 0.1 1.7 1 1 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 EMT52841.1 - 0.017 15.0 0.0 0.064 13.2 0.0 2.0 2 0 0 2 2 1 0 NACHT domain ABC_tran PF00005.27 EMT52841.1 - 0.018 15.6 0.0 0.053 14.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EMT52841.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 EMT52841.1 - 0.021 14.1 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 PduV-EutP PF10662.9 EMT52841.1 - 0.031 14.0 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EMT52841.1 - 0.032 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EMT52841.1 - 0.042 13.7 0.2 0.086 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PhoH PF02562.16 EMT52841.1 - 0.044 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 EMT52841.1 - 0.046 13.7 0.2 0.17 11.9 0.1 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 EMT52841.1 - 0.067 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EMT52841.1 - 0.067 13.0 0.4 0.3 10.8 0.0 2.1 2 1 0 3 3 3 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 EMT52841.1 - 0.069 13.5 0.0 0.19 12.1 0.0 1.9 1 1 0 1 1 1 0 RNA helicase ATPase PF06745.13 EMT52841.1 - 0.075 12.4 0.9 0.9 8.8 0.6 2.2 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.6 EMT52841.1 - 0.17 11.4 0.4 0.72 9.4 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMT52841.1 - 0.17 12.2 0.8 0.8 10.0 0.1 2.3 2 1 1 3 3 2 0 AAA domain C1_2 PF03107.16 EMT52841.1 - 0.22 11.9 1.9 0.46 10.8 1.9 1.5 1 0 0 1 1 1 0 C1 domain CLP_protease PF00574.23 EMT52842.1 - 1.1e-87 292.7 0.0 1.2e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 Clp protease Trigger_N PF05697.13 EMT52843.1 - 8.2e-46 155.8 11.7 4.2e-45 153.5 4.3 3.3 3 1 0 3 3 3 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 EMT52843.1 - 6.9e-43 146.5 7.7 6.9e-43 146.5 7.7 2.4 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 EMT52843.1 - 2.8e-16 59.6 5.3 8.2e-16 58.1 1.1 3.1 2 1 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Osmo_CC PF08946.10 EMT52843.1 - 0.0069 16.6 1.1 0.91 9.8 0.2 2.8 2 0 0 2 2 2 1 Osmosensory transporter coiled coil SurA_N_3 PF13624.6 EMT52843.1 - 0.4 10.5 10.1 0.29 10.9 4.5 2.9 2 1 1 3 3 3 0 SurA N-terminal domain Metallophos_2 PF12850.7 EMT52844.1 - 1.9e-29 103.0 0.0 2.3e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EMT52844.1 - 1.4e-05 25.7 0.4 0.0097 16.4 0.0 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Ham1p_like PF01725.16 EMT52845.1 - 1.1e-61 208.0 0.0 1.2e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AP_endonuc_2 PF01261.24 EMT52845.1 - 0.04 13.3 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel RNase_PH PF01138.21 EMT52846.1 - 1.7e-24 86.8 0.0 2.8e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EMT52846.1 - 8.6e-14 51.3 0.2 1.5e-13 50.5 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Germane PF10646.9 EMT52847.1 - 8.7e-43 145.3 2.7 8.9e-22 77.8 0.2 2.2 2 0 0 2 2 2 2 Sporulation and spore germination Big_7 PF17957.1 EMT52847.1 - 0.037 14.8 0.2 4.3 8.2 0.2 3.3 2 1 1 3 3 3 0 Bacterial Ig domain LPAM_2 PF13627.6 EMT52847.1 - 0.12 12.3 3.1 0.22 11.4 3.1 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Asp_Glu_race PF01177.22 EMT52848.1 - 7.3e-33 114.3 0.1 8.7e-33 114.0 0.1 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Sod_Fe_C PF02777.18 EMT52849.1 - 9.1e-34 115.7 2.1 1.1e-33 115.5 0.7 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EMT52849.1 - 4.9e-27 94.2 1.2 4.9e-27 94.2 1.2 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF2935 PF11155.8 EMT52849.1 - 0.0052 17.1 0.5 0.014 15.7 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) DUF3899 PF13038.6 EMT52850.1 - 7.6e-16 58.4 2.3 7.6e-16 58.4 2.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3899) MscS_TM PF12794.7 EMT52850.1 - 0.88 8.4 9.5 0.048 12.5 3.7 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 ABC_tran PF00005.27 EMT52851.1 - 1.7e-33 116.0 0.0 2.3e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT52851.1 - 1.1e-16 61.1 0.2 2e-16 60.3 0.2 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EMT52851.1 - 7.7e-05 22.2 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.25 EMT52851.1 - 0.00067 19.4 0.0 0.00082 19.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 EMT52851.1 - 0.0033 17.7 0.3 0.012 15.8 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT52851.1 - 0.0035 17.7 0.2 0.0053 17.2 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EMT52851.1 - 0.013 15.3 0.2 4.3 7.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EMT52851.1 - 0.021 15.3 0.0 0.076 13.4 0.0 1.8 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EMT52851.1 - 0.021 14.5 0.2 0.04 13.6 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMT52851.1 - 0.033 14.1 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 EMT52851.1 - 0.07 13.1 0.1 0.27 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EMT52851.1 - 0.19 10.9 0.1 0.29 10.3 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 EMT52852.1 - 1.1e-31 110.1 0.0 1.6e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT52852.1 - 2.9e-21 75.8 0.0 5.1e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT52852.1 - 2e-06 27.8 0.1 3.4e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT52852.1 - 3.9e-06 26.5 0.0 1.2e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT52852.1 - 0.0007 19.9 0.8 0.1 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EMT52852.1 - 0.00087 18.7 2.2 0.2 11.0 1.3 3.0 2 1 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 EMT52852.1 - 0.0061 16.0 0.1 0.078 12.4 0.0 2.3 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EMT52852.1 - 0.011 15.4 0.6 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 EMT52852.1 - 0.032 14.6 0.4 0.093 13.1 0.4 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EMT52852.1 - 0.039 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EMT52852.1 - 0.062 13.7 0.2 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 EMT52852.1 - 0.075 12.7 0.2 0.1 12.2 0.2 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 EMT52852.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EMT52852.1 - 0.099 12.3 0.3 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 EMT52852.1 - 0.11 12.4 0.1 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 EMT52852.1 - 0.19 11.8 0.2 0.78 9.8 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain BPD_transp_1 PF00528.22 EMT52853.1 - 8.3e-33 113.7 15.2 1.5e-32 112.8 10.9 2.3 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT52853.1 - 1.9e-13 50.1 0.1 1.9e-13 50.1 0.1 3.5 5 0 0 5 5 5 1 N-terminal TM domain of oligopeptide transport permease C DUF3169 PF11368.8 EMT52853.1 - 3.4 7.1 9.8 1.8 8.0 6.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) BPD_transp_1 PF00528.22 EMT52854.1 - 1.1e-38 132.8 20.5 1.1e-38 132.8 20.5 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4337 PF14235.6 EMT52854.1 - 0.74 9.9 3.7 1.3 9.1 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Renin_r PF07850.14 EMT52854.1 - 1.4 9.6 7.1 0.36 11.4 0.6 2.7 2 0 0 2 2 2 0 Renin receptor-like protein Peptidase_M20 PF01546.28 EMT52855.1 - 4.8e-30 104.8 0.0 6.4e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT52855.1 - 7e-05 22.7 0.0 0.11 12.4 0.0 3.0 2 1 0 2 2 2 2 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT52855.1 - 0.16 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Sigma54_activat PF00158.26 EMT52856.1 - 7.7e-68 227.4 1.3 1.4e-67 226.6 0.1 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT52856.1 - 1.1e-19 70.9 0.0 4.1e-19 69.1 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EMT52856.1 - 3.9e-09 36.6 0.0 9.8e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_12 PF08461.10 EMT52856.1 - 4.6e-07 29.7 0.7 1.5e-06 28.0 0.7 1.9 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Mg_chelatase PF01078.21 EMT52856.1 - 1.1e-06 28.1 0.1 6e-05 22.5 0.1 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EMT52856.1 - 1.4e-06 28.5 0.0 5e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EMT52856.1 - 2.5e-06 28.0 0.0 5.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EMT52856.1 - 0.0029 17.2 0.0 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region PAS_8 PF13188.7 EMT52856.1 - 0.0092 16.0 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 PAS domain AAA_PrkA PF08298.11 EMT52856.1 - 0.014 14.3 0.0 0.14 11.1 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain MCM PF00493.23 EMT52856.1 - 0.017 14.2 0.0 0.06 12.4 0.0 1.9 1 1 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 EMT52856.1 - 0.019 15.3 0.1 0.059 13.7 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain Parvo_NS1 PF01057.17 EMT52856.1 - 0.022 13.8 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HTH_20 PF12840.7 EMT52856.1 - 0.025 14.6 0.1 0.067 13.3 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain PAS PF00989.25 EMT52856.1 - 0.026 14.5 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 PAS fold IstB_IS21 PF01695.17 EMT52856.1 - 0.029 14.1 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EMT52856.1 - 0.048 13.4 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 EMT52856.1 - 0.061 13.2 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EMT52856.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 EMT52856.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein SBP_bac_5 PF00496.22 EMT52857.1 - 1.2e-85 287.8 10.6 1.9e-85 287.1 10.6 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle HI0933_like PF03486.14 EMT52857.1 - 0.13 10.9 0.0 0.54 8.9 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein ABC2_membrane_3 PF12698.7 EMT52857.1 - 0.14 11.3 3.2 0.81 8.7 3.3 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein Asparaginase_II PF06089.12 EMT52858.1 - 2.8e-122 407.8 0.1 3.2e-122 407.6 0.1 1.0 1 0 0 1 1 1 1 L-asparaginase II DUF2098 PF09871.9 EMT52859.1 - 0.044 14.1 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) ETF_QO PF05187.13 EMT52860.1 - 5.5e-11 42.5 2.4 6.8e-11 42.2 2.4 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_10 PF13237.6 EMT52860.1 - 2.9e-05 24.1 8.0 4.4e-05 23.5 8.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EMT52860.1 - 0.00023 21.3 10.0 0.00078 19.6 10.0 1.8 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EMT52860.1 - 0.0011 18.9 10.7 0.05 13.7 1.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EMT52860.1 - 0.0015 19.0 10.6 0.1 13.2 1.9 2.6 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EMT52860.1 - 0.0032 17.8 13.4 0.015 15.7 1.9 2.8 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4 PF00037.27 EMT52860.1 - 0.027 14.3 2.1 0.027 14.3 2.1 3.1 2 1 1 3 3 3 0 4Fe-4S binding domain Fer4_16 PF13484.6 EMT52860.1 - 0.069 14.1 1.4 0.069 14.1 1.4 2.9 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain zinc_ribbon_6 PF14599.6 EMT52860.1 - 0.25 11.4 4.8 0.48 10.5 4.8 1.5 1 1 0 1 1 1 0 Zinc-ribbon Fer4_17 PF13534.6 EMT52860.1 - 0.25 11.9 12.0 15 6.2 12.2 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 EMT52860.1 - 0.62 10.6 12.5 23 5.5 12.5 2.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain DAO PF01266.24 EMT52861.1 - 1.5e-15 57.7 0.0 5.4e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMT52861.1 - 2.4e-14 53.4 1.4 1.2e-09 37.9 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EMT52861.1 - 6.8e-10 38.6 0.1 3e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EMT52861.1 - 2e-09 37.3 0.0 4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMT52861.1 - 3.8e-09 35.7 0.4 2.1e-08 33.3 0.4 2.1 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EMT52861.1 - 5.1e-09 35.8 0.0 1.4e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMT52861.1 - 7e-09 35.2 0.1 3.1e-06 26.6 0.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EMT52861.1 - 1.4e-08 34.8 0.4 4.4e-08 33.2 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMT52861.1 - 1.1e-07 31.3 0.5 1.1e-07 31.3 0.5 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 EMT52861.1 - 5.1e-06 26.0 0.0 3.4e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMT52861.1 - 6.7e-05 22.1 0.4 0.00016 20.9 0.4 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EMT52861.1 - 0.0002 20.4 0.8 0.39 9.5 0.0 2.4 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.27 EMT52861.1 - 0.0044 17.5 2.9 0.01 16.3 0.1 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 EMT52861.1 - 0.01 14.4 0.0 1.4 7.3 0.0 2.4 2 0 0 2 2 2 0 GDP dissociation inhibitor ApbA PF02558.16 EMT52861.1 - 0.014 15.0 0.2 0.033 13.8 0.1 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.19 EMT52861.1 - 0.023 14.1 0.0 4.9 6.4 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase 3HCDH_N PF02737.18 EMT52861.1 - 0.031 14.1 0.3 0.088 12.7 0.3 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EMT52861.1 - 0.26 11.3 1.3 2 8.4 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding ETF PF01012.21 EMT52862.1 - 2.5e-46 157.9 0.2 6.6e-46 156.5 0.0 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EMT52862.1 - 7.8e-36 122.0 2.8 1.9e-35 120.7 2.8 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 EMT52863.1 - 3.3e-44 151.0 0.0 4.1e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Usp PF00582.26 EMT52863.1 - 0.00073 20.1 0.1 0.31 11.6 0.0 3.1 2 1 0 2 2 2 1 Universal stress protein family Na_Ala_symp PF01235.17 EMT52864.1 - 5.7e-150 500.0 38.9 8.1e-150 499.5 38.9 1.1 1 0 0 1 1 1 1 Sodium:alanine symporter family TrmB PF01978.19 EMT52865.1 - 1.5e-17 63.2 0.0 2.9e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 EMT52865.1 - 2.8e-05 23.4 0.1 3.9e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_IclR PF09339.10 EMT52865.1 - 0.00037 20.3 0.0 0.0007 19.3 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain Penicillinase_R PF03965.16 EMT52865.1 - 0.027 14.8 0.1 0.05 14.0 0.1 1.6 1 0 0 1 1 1 0 Penicillinase repressor PadR PF03551.14 EMT52865.1 - 0.037 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family MarR_2 PF12802.7 EMT52865.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 MarR family MFS_1 PF07690.16 EMT52866.1 - 2.1e-42 145.4 53.1 1e-39 136.5 46.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EMT52866.1 - 2.3e-05 23.9 30.2 3.1e-05 23.4 30.2 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EMT52866.1 - 0.028 13.3 28.4 0.26 10.1 11.1 3.0 1 1 0 2 2 2 0 MFS_1 like family TMEM238 PF15125.6 EMT52866.1 - 0.029 14.6 1.3 0.029 14.6 1.3 4.1 4 1 0 4 4 4 0 TMEM238 protein family APH PF01636.23 EMT52868.1 - 8.3e-06 25.9 1.4 1.1e-05 25.5 1.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Acetyltransf_1 PF00583.25 EMT52869.1 - 9.7e-13 48.4 0.0 1.1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT52869.1 - 1.1e-08 35.0 0.1 1.5e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT52869.1 - 3.2e-08 33.9 0.0 5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT52869.1 - 2.3e-06 27.5 0.0 4.1e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EMT52869.1 - 0.00071 19.8 0.3 0.0011 19.1 0.3 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMT52869.1 - 0.00071 20.3 0.1 0.00085 20.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT52869.1 - 0.042 13.9 0.1 0.098 12.7 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT52869.1 - 0.047 13.8 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase ParBc_2 PF08857.11 EMT52869.1 - 0.05 13.7 0.1 0.056 13.5 0.1 1.2 1 1 0 1 1 1 0 Putative ParB-like nuclease Acetyltransf_8 PF13523.6 EMT52869.1 - 0.071 12.8 0.1 0.1 12.3 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 EMT52869.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region HATPase_c_5 PF14501.6 EMT52870.1 - 4.1e-19 68.4 0.0 2.9e-18 65.6 0.0 2.2 2 0 0 2 2 2 1 GHKL domain HATPase_c PF02518.26 EMT52870.1 - 1e-16 61.4 0.0 2.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPOB_a PF14689.6 EMT52870.1 - 6.9e-16 57.7 0.5 1.7e-15 56.4 0.5 1.8 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain sCache_3_2 PF17203.4 EMT52870.1 - 8.9e-06 25.9 0.3 1.6e-05 25.0 0.3 1.4 1 0 0 1 1 1 1 Single cache domain 3 dCache_1 PF02743.18 EMT52870.1 - 0.00023 21.0 0.2 0.00047 20.0 0.1 1.6 2 0 0 2 2 2 1 Cache domain HATPase_c_2 PF13581.6 EMT52870.1 - 0.00062 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Trypsin_2 PF13365.6 EMT52870.1 - 0.024 15.6 0.0 0.035 15.0 0.0 1.3 1 0 0 1 1 1 0 Trypsin-like peptidase domain sCache_3_3 PF17202.4 EMT52870.1 - 0.083 13.3 0.4 0.32 11.4 0.4 1.9 2 0 0 2 2 2 0 Single cache domain 3 Cache_3-Cache_2 PF17201.4 EMT52870.1 - 0.11 11.8 1.2 0.15 11.3 0.4 1.6 2 0 0 2 2 2 0 Cache 3/Cache 2 fusion domain Peptidase_M20 PF01546.28 EMT52871.1 - 2.5e-09 37.2 0.0 1.1e-08 35.1 0.0 2.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EMT52871.1 - 0.0033 17.2 0.0 0.014 15.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M28 Colicin_Pyocin PF01320.18 EMT52871.1 - 0.035 14.2 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein Peptidase_M20 PF01546.28 EMT52872.1 - 2.8e-32 112.1 0.7 3.6e-32 111.8 0.7 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT52872.1 - 1.6e-14 53.8 0.1 8.6e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain FAD_binding_3 PF01494.19 EMT52873.1 - 1.7e-21 76.9 1.4 9.2e-11 41.6 0.3 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EMT52873.1 - 0.00065 19.9 1.4 0.002 18.3 1.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMT52873.1 - 0.013 15.1 4.7 0.014 15.0 3.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMT52873.1 - 0.064 12.3 3.7 0.11 11.5 3.7 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EMT52873.1 - 0.079 12.2 1.5 0.19 11.0 1.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT52873.1 - 0.14 11.4 1.2 0.74 9.0 2.3 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT52873.1 - 0.46 9.1 2.3 0.67 8.6 2.3 1.2 1 0 0 1 1 1 0 HI0933-like protein PEP-utilizers_C PF02896.18 EMT52874.1 - 2.2e-115 384.8 0.0 2.9e-115 384.4 0.0 1.1 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 EMT52874.1 - 2.8e-29 101.6 3.5 2.8e-29 101.6 3.5 2.1 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 EMT52874.1 - 9.7e-24 82.9 1.8 2.4e-23 81.6 1.8 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Nuc_rec_co-act PF08815.10 EMT52874.1 - 0.056 13.3 0.1 0.16 11.8 0.1 1.8 1 0 0 1 1 1 0 Nuclear receptor coactivator PTS-HPr PF00381.19 EMT52875.1 - 3.3e-30 104.1 0.3 3.6e-30 104.0 0.3 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site KDGP_aldolase PF07071.11 EMT52876.1 - 1.5e-79 266.8 0.5 1.9e-79 266.5 0.5 1.0 1 0 0 1 1 1 1 KDGP aldolase Aldolase PF01081.19 EMT52876.1 - 0.0056 16.1 1.1 0.0092 15.4 0.3 1.7 1 1 1 2 2 2 1 KDPG and KHG aldolase SelA PF03841.13 EMT52877.1 - 4.2e-13 49.0 4.2 1.6e-11 43.9 4.3 3.0 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Cys_Met_Meta_PP PF01053.20 EMT52877.1 - 1.4e-06 27.1 0.0 2.9e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EMT52877.1 - 7.6e-06 25.4 0.4 1.5e-05 24.5 0.4 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EMT52877.1 - 5.5e-05 22.3 0.3 8.8e-05 21.6 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-V SBD_N PF07005.11 EMT52877.1 - 0.0007 19.4 0.2 0.0017 18.2 0.2 1.6 1 0 0 1 1 1 1 Sugar-binding N-terminal domain DegT_DnrJ_EryC1 PF01041.17 EMT52877.1 - 0.0028 17.0 3.1 1.1 8.5 0.3 2.5 3 0 0 3 3 3 2 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EMT52877.1 - 0.01 14.4 0.1 0.015 13.9 0.1 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase peroxidase PF00141.23 EMT52877.1 - 0.027 14.2 0.4 2.5 7.8 0.1 2.2 1 1 1 2 2 2 0 Peroxidase DUF4310 PF14187.6 EMT52878.1 - 6.3e-105 349.4 29.6 7.1e-105 349.2 29.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4310) QCR10 PF09796.9 EMT52878.1 - 0.47 10.6 6.7 2.5 8.2 1.7 3.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF4311 PF14188.6 EMT52879.1 - 1.3e-120 401.0 10.9 1.9e-120 400.4 10.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4311) DUF2232 PF09991.9 EMT52879.1 - 0.073 12.2 6.5 0.057 12.6 4.3 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) Ni_hydr_CYTB PF01292.20 EMT52879.1 - 0.1 12.2 6.5 0.56 9.8 1.1 2.3 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF4312 PF14189.6 EMT52880.1 - 1.4e-26 92.3 0.2 1.8e-26 91.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4312) Gly_rich_SFCGS PF14272.6 EMT52881.1 - 2.3e-59 198.3 5.4 2.6e-59 198.2 5.4 1.0 1 0 0 1 1 1 1 Glycine-rich SFCGS DUF2620 PF10941.8 EMT52881.1 - 0.0037 17.4 3.2 0.013 15.6 2.2 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF2620 PRD PF00874.20 EMT52882.1 - 0.01 16.1 0.1 0.057 13.7 0.1 2.2 1 1 1 2 2 2 0 PRD domain Amidohydro_3 PF07969.11 EMT52883.1 - 1e-18 68.1 0.6 2.4e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EMT52883.1 - 3.6e-15 56.1 0.2 1.4e-13 50.9 0.2 2.4 1 1 0 1 1 1 1 Amidohydrolase family PRD PF00874.20 EMT52884.1 - 2.6e-20 72.5 0.0 6.4e-11 42.4 0.0 3.5 3 0 0 3 3 3 3 PRD domain Mga PF05043.13 EMT52884.1 - 9.8e-12 45.3 0.5 5.5e-06 26.9 0.1 2.9 2 1 0 2 2 2 2 Mga helix-turn-helix domain HTH_11 PF08279.12 EMT52884.1 - 1.6e-11 43.9 0.7 0.00011 22.1 0.1 2.9 3 0 0 3 3 3 2 HTH domain HTH_DeoR PF08220.12 EMT52884.1 - 1.2e-06 28.1 0.3 0.0077 16.0 0.1 2.9 2 0 0 2 2 2 2 DeoR-like helix-turn-helix domain Sigma70_ECF PF07638.11 EMT52884.1 - 0.00087 19.2 0.1 0.0038 17.1 0.0 2.1 3 0 0 3 3 3 1 ECF sigma factor PTS_IIB PF02302.17 EMT52884.1 - 0.0016 19.1 0.1 0.03 15.0 0.0 2.9 3 1 0 3 3 3 1 PTS system, Lactose/Cellobiose specific IIB subunit UPF0122 PF04297.14 EMT52884.1 - 0.0087 16.3 0.7 1.6 9.0 0.0 2.7 1 1 1 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_Mga PF08280.11 EMT52884.1 - 0.011 15.8 0.1 0.026 14.5 0.1 1.7 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_28 PF13518.6 EMT52884.1 - 0.027 14.6 0.0 18 5.6 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 EMT52884.1 - 0.028 14.2 0.0 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 Homeodomain-like domain GerE PF00196.19 EMT52884.1 - 0.032 13.8 0.0 0.25 10.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_AraC PF00165.23 EMT52884.1 - 0.047 13.8 0.0 4.5 7.5 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_10 PF04967.12 EMT52884.1 - 0.05 13.4 0.0 18 5.2 0.0 2.6 2 0 0 2 2 2 0 HTH DNA binding domain SpoIIID PF12116.8 EMT52884.1 - 0.068 13.3 0.1 4.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Stage III sporulation protein D HTH_7 PF02796.15 EMT52884.1 - 0.075 13.1 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DUF746 PF05344.11 EMT52884.1 - 0.079 12.8 0.0 7.8 6.4 0.0 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) HTH_5 PF01022.20 EMT52884.1 - 0.087 12.7 0.0 10 6.0 0.0 3.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family LacI PF00356.21 EMT52884.1 - 0.087 12.6 0.1 6 6.7 0.0 3.2 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family Phage_terminase PF10668.9 EMT52884.1 - 0.098 12.7 0.5 4.4 7.4 0.0 3.1 3 0 0 3 3 3 0 Phage terminase small subunit NUMOD1 PF07453.13 EMT52884.1 - 0.12 12.7 0.0 8.1 6.8 0.0 2.4 2 0 0 2 2 2 0 NUMOD1 domain HTH_47 PF16221.5 EMT52884.1 - 0.12 11.9 0.0 0.36 10.4 0.0 1.8 1 0 0 1 1 1 0 winged helix-turn-helix PALP PF00291.25 EMT52885.1 - 5.4e-70 236.1 0.3 6.2e-70 235.9 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 EMT52885.1 - 0.0043 17.0 0.2 0.012 15.5 0.1 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DFP PF04127.15 EMT52885.1 - 0.049 13.5 0.2 1.1 9.0 0.1 2.2 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein Beta_elim_lyase PF01212.21 EMT52886.1 - 6e-35 120.9 0.0 7.5e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EMT52886.1 - 2.7e-05 23.7 0.0 0.00015 21.2 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.21 EMT52886.1 - 0.048 12.3 0.1 2.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMT52886.1 - 0.061 12.5 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II DUF1495 PF07381.11 EMT52887.1 - 0.039 13.8 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) DUF1843 PF08898.10 EMT52888.1 - 0.022 15.3 0.2 1.1 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF1732 PF08340.11 EMT52888.1 - 0.033 14.2 0.1 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) UPF0184 PF03670.13 EMT52888.1 - 0.037 14.4 0.1 0.54 10.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) FliT PF05400.13 EMT52888.1 - 0.11 13.3 0.0 1.4 9.8 0.0 2.0 2 0 0 2 2 2 0 Flagellar protein FliT CxxCxxCC PF03692.15 EMT52889.1 - 9e-07 29.5 0.2 1.1e-06 29.2 0.2 1.2 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain DUF3231 PF11553.8 EMT52890.1 - 5e-38 130.3 0.0 5.5e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3231) Coat_F PF07875.12 EMT52890.1 - 2.2e-05 24.6 0.0 0.0083 16.3 0.0 2.1 2 0 0 2 2 2 2 Coat F domain Filo_glycop PF01611.16 EMT52890.1 - 0.081 11.9 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein DUF2383 PF09537.10 EMT52890.1 - 0.17 12.3 0.0 0.47 10.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) DUF2243 PF10002.9 EMT52891.1 - 1.1e-36 126.1 12.0 1.2e-36 125.9 12.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) MARVEL PF01284.23 EMT52891.1 - 0.013 15.5 4.6 0.078 13.0 1.0 2.3 1 1 1 2 2 2 0 Membrane-associating domain ECF_trnsprt PF12822.7 EMT52891.1 - 0.06 13.5 3.5 0.077 13.1 3.5 1.2 1 0 0 1 1 1 0 ECF transporter, substrate-specific component DUF2583 PF10762.9 EMT52891.1 - 0.086 13.3 7.2 0.13 12.7 3.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) DUF4383 PF14325.6 EMT52891.1 - 1 9.7 7.9 2.1 8.6 7.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) Spore_YabQ PF09578.10 EMT52891.1 - 1.4 9.2 11.8 0.32 11.3 4.7 2.4 1 1 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) DUF4064 PF13273.6 EMT52891.1 - 8.6 6.7 11.0 4.5 7.6 6.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Methyltransf_3 PF01596.17 EMT52892.1 - 9.7e-42 142.5 0.0 1.2e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EMT52892.1 - 4e-17 63.2 0.0 7.1e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT52892.1 - 8.9e-07 28.8 0.0 6.9e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMT52892.1 - 3.9e-05 23.5 0.0 7.7e-05 22.5 0.0 1.4 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 EMT52892.1 - 0.0062 16.2 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Cons_hypoth95 PF03602.15 EMT52892.1 - 0.0077 15.9 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EMT52892.1 - 0.014 16.0 0.0 0.026 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EMT52892.1 - 0.019 14.6 0.0 0.025 14.2 0.0 1.4 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 EMT52892.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF1442 PF07279.11 EMT52892.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) PadR PF03551.14 EMT52893.1 - 6e-20 71.0 0.3 9.3e-20 70.4 0.3 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.6 EMT52893.1 - 0.0025 17.7 0.1 0.0043 17.0 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DUF505 PF04458.12 EMT52893.1 - 0.0035 15.8 0.4 0.0055 15.1 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF505) DUF4364 PF14277.6 EMT52893.1 - 0.015 15.1 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) RTP PF02334.16 EMT52893.1 - 0.024 15.3 0.2 0.073 13.7 0.1 1.8 2 1 0 2 2 2 0 Replication terminator protein HTH_27 PF13463.6 EMT52893.1 - 0.11 13.0 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain Crystall PF00030.19 EMT52895.1 - 0.03 14.5 0.0 0.062 13.5 0.0 1.5 1 1 0 1 1 1 0 Beta/Gamma crystallin IL4_i_Ig PF18258.1 EMT52895.1 - 0.073 13.3 0.0 5.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Interleukin-4 inducing immunoglobulin-binding domain NOP5NT PF08156.13 EMT52896.1 - 0.55 10.7 7.2 2.5 8.5 1.1 2.2 1 1 1 2 2 2 0 NOP5NT (NUC127) domain DUF4183 PF13799.6 EMT52897.1 - 2.4e-20 72.1 3.4 2.9e-20 71.8 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4183) GerE PF00196.19 EMT52898.1 - 4.1e-24 83.9 0.1 4.7e-24 83.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EMT52898.1 - 1e-10 41.1 0.1 4e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT52898.1 - 1.7e-07 30.6 0.5 6e-07 28.9 0.1 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 EMT52898.1 - 0.00089 18.6 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 EMT52898.1 - 0.0009 19.1 0.1 0.0011 18.9 0.1 1.2 1 0 0 1 1 1 1 HTH domain HTH_10 PF04967.12 EMT52898.1 - 0.001 18.8 0.2 0.004 16.9 0.0 1.8 2 0 0 2 2 2 1 HTH DNA binding domain Trans_reg_C PF00486.28 EMT52898.1 - 0.002 18.2 0.3 0.049 13.7 0.3 2.0 1 1 0 1 1 1 1 Transcriptional regulatory protein, C terminal UPF0122 PF04297.14 EMT52898.1 - 0.0037 17.5 0.0 0.0049 17.1 0.0 1.1 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_23 PF13384.6 EMT52898.1 - 0.0038 17.0 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain KORA PF16509.5 EMT52898.1 - 0.0044 17.3 0.3 0.0055 17.0 0.3 1.2 1 0 0 1 1 1 1 TrfB plasmid transcriptional repressor HTH_40 PF14493.6 EMT52898.1 - 0.0045 17.4 0.1 0.0047 17.4 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2089 PF09862.9 EMT52898.1 - 0.0098 15.9 0.1 0.011 15.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) HTH_DeoR PF08220.12 EMT52898.1 - 0.024 14.4 0.1 0.045 13.5 0.1 1.5 1 1 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 EMT52898.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_30 PF13556.6 EMT52898.1 - 0.025 14.4 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Mga PF05043.13 EMT52898.1 - 0.048 14.2 0.0 0.061 13.9 0.0 1.2 1 0 0 1 1 1 0 Mga helix-turn-helix domain DUF5383 PF17355.2 EMT52898.1 - 0.051 14.0 0.0 0.058 13.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Phage_terminase PF10668.9 EMT52898.1 - 0.082 12.9 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 Phage terminase small subunit HTH_Mga PF08280.11 EMT52898.1 - 0.1 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_38 PF13936.6 EMT52898.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain BPD_transp_1 PF00528.22 EMT52899.1 - 2e-09 37.4 10.7 2e-09 37.4 10.7 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT52899.1 - 0.0002 21.3 0.0 0.0002 21.3 0.0 3.7 5 0 0 5 5 5 2 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 EMT52900.1 - 1.2e-14 54.5 22.5 1.8e-14 53.9 21.4 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component PHO4 PF01384.20 EMT52900.1 - 5.3 6.0 6.9 5.8 5.9 5.6 1.7 1 1 0 1 1 1 0 Phosphate transporter family CheX PF13690.6 EMT52901.1 - 4.8e-13 49.1 0.0 6.5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Chemotaxis phosphatase CheX CheC PF04509.12 EMT52901.1 - 6.4e-12 45.2 0.2 1.3e-11 44.2 0.2 1.5 1 0 0 1 1 1 1 CheC-like family Big_6 PF17936.1 EMT52903.1 - 0.00086 19.5 0.1 0.00093 19.4 0.1 1.0 1 0 0 1 1 1 1 Bacterial Ig domain Resolvase PF00239.21 EMT52903.1 - 0.026 14.6 0.0 0.027 14.6 0.0 1.0 1 0 0 1 1 1 0 Resolvase, N terminal domain MFS_1 PF07690.16 EMT52904.1 - 3e-51 174.4 68.8 1.6e-50 172.0 65.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT52904.1 - 5.7e-08 32.0 48.3 5.3e-06 25.6 18.5 3.7 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 EMT52904.1 - 8.6e-08 31.1 48.0 9.2e-06 24.5 17.8 3.6 3 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 EMT52904.1 - 5.6e-05 21.8 35.0 9.7e-05 21.0 34.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EMT52904.1 - 0.0028 16.0 9.0 0.0028 16.0 9.0 3.0 2 2 2 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family Fer2_3 PF13085.6 EMT52905.1 - 1.6e-30 105.3 0.8 2e-30 105.0 0.0 1.5 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 EMT52905.1 - 1.2e-09 38.4 5.8 1.6e-09 38.0 2.6 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMT52905.1 - 8.3e-09 35.4 2.6 8.3e-09 35.4 2.6 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EMT52905.1 - 3.9e-08 33.8 4.7 0.00053 20.5 0.1 3.2 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EMT52905.1 - 8.8e-08 32.2 3.8 0.00071 19.7 0.1 3.2 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EMT52905.1 - 2.9e-05 24.5 6.4 2.9e-05 24.5 6.4 2.7 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EMT52905.1 - 0.00023 21.1 15.5 0.0011 18.9 1.3 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 EMT52905.1 - 0.00029 21.0 6.3 0.078 13.2 0.0 2.9 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 EMT52905.1 - 0.0018 18.0 17.5 0.0019 17.9 2.8 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_13 PF13370.6 EMT52905.1 - 0.013 16.0 0.1 0.013 16.0 0.1 3.0 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_20 PF14691.6 EMT52905.1 - 0.025 14.3 8.9 0.45 10.3 0.2 2.9 2 1 1 3 3 3 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_16 PF13484.6 EMT52905.1 - 0.025 15.5 14.2 0.43 11.5 11.2 3.2 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain Fer4_15 PF13459.6 EMT52905.1 - 0.049 14.4 2.8 0.32 11.8 0.5 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.7 EMT52905.1 - 0.064 13.8 0.8 0.064 13.8 0.8 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_21 PF14697.6 EMT52905.1 - 0.07 13.3 9.1 0.16 12.1 1.0 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EMT52905.1 - 0.077 14.0 0.8 0.077 14.0 0.8 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_6 PF12837.7 EMT52905.1 - 0.18 12.0 15.5 0.51 10.5 1.8 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain FAD_binding_2 PF00890.24 EMT52906.1 - 6.3e-88 295.6 0.1 9.1e-88 295.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EMT52906.1 - 1e-43 148.4 0.2 1.5e-43 147.8 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EMT52906.1 - 7.5e-07 28.7 0.6 0.0023 17.2 0.2 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMT52906.1 - 1.9e-05 23.9 2.0 0.00011 21.4 0.5 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EMT52906.1 - 0.0022 16.8 0.4 0.0022 16.8 0.4 3.0 4 0 0 4 4 4 1 HI0933-like protein FAD_oxidored PF12831.7 EMT52906.1 - 0.015 14.7 2.5 0.023 14.1 0.3 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMT52906.1 - 0.034 14.7 0.9 8.7 7.0 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMT52906.1 - 0.055 13.7 0.3 0.18 12.1 0.3 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EMT52906.1 - 0.074 12.3 0.4 0.5 9.6 0.9 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Sdh_cyt PF01127.22 EMT52907.1 - 1.1e-15 57.8 20.5 4e-11 43.0 8.3 2.0 1 1 1 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1691 PF07950.11 EMT52907.1 - 0.046 14.4 7.0 0.54 11.0 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) DUF2507 PF10702.9 EMT52908.1 - 2e-24 85.9 0.0 2.4e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2507) YdaS_antitoxin PF15943.5 EMT52908.1 - 0.088 12.7 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT AA_kinase PF00696.28 EMT52909.1 - 4.5e-52 177.0 2.5 7e-52 176.4 2.5 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 EMT52909.1 - 5.8e-19 67.7 1.6 1.3e-13 50.5 0.1 2.8 2 1 0 2 2 2 2 ACT domain ACT PF01842.25 EMT52909.1 - 1.9e-16 59.5 0.6 1.7e-09 37.3 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 EMT52909.1 - 0.00045 20.2 0.7 0.17 11.9 0.0 3.1 3 0 0 3 3 3 2 ACT domain ACT_4 PF13291.6 EMT52909.1 - 0.0012 19.4 2.5 1.8 9.2 0.0 3.4 3 0 0 3 3 3 2 ACT domain UvrC_HhH_N PF08459.11 EMT52910.1 - 7.7e-58 194.8 0.0 1.5e-57 193.8 0.0 1.5 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal UVR PF02151.19 EMT52910.1 - 2.3e-11 43.0 7.8 7.2e-11 41.5 7.8 1.9 1 0 0 1 1 1 1 UvrB/uvrC motif GIY-YIG PF01541.24 EMT52910.1 - 2.8e-10 40.3 0.2 1.7e-09 37.8 0.1 2.3 2 0 0 2 2 2 1 GIY-YIG catalytic domain HHH_5 PF14520.6 EMT52910.1 - 3.8e-07 30.6 0.3 1.5e-06 28.7 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EMT52910.1 - 7.5e-07 29.2 0.0 1.9e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 EMT52910.1 - 0.033 14.0 0.0 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 EMT52910.1 - 0.088 13.4 0.5 0.63 10.7 0.0 2.6 2 1 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold HHH_3 PF12836.7 EMT52910.1 - 0.099 12.9 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF1104 PF06518.11 EMT52910.1 - 3.1 8.2 8.4 0.43 11.0 2.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) DUF2164 PF09932.9 EMT52911.1 - 3.4e-27 94.3 0.3 3.9e-27 94.1 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2164) Thioredoxin PF00085.20 EMT52912.1 - 7.3e-31 106.2 0.0 7.9e-31 106.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EMT52912.1 - 2.1e-09 37.6 0.0 6.9e-07 29.5 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EMT52912.1 - 2.8e-09 37.4 0.0 6.8e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EMT52912.1 - 3e-06 27.0 0.0 3.6e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EMT52912.1 - 3.9e-05 23.4 0.0 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 EMT52912.1 - 0.00021 21.2 0.0 0.00025 20.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 EMT52912.1 - 0.0003 20.7 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EMT52912.1 - 0.00035 20.7 0.0 0.00045 20.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 EMT52912.1 - 0.00073 19.5 0.0 0.00091 19.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain KaiB PF07689.12 EMT52912.1 - 0.0017 18.0 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 KaiB domain Glutaredoxin PF00462.24 EMT52912.1 - 0.0091 16.2 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin OST3_OST6 PF04756.13 EMT52912.1 - 0.02 14.2 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family HyaE PF07449.11 EMT52912.1 - 0.038 13.9 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF836 PF05768.14 EMT52912.1 - 0.045 14.2 0.0 0.061 13.7 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF953 PF06110.11 EMT52912.1 - 0.16 11.6 0.2 0.85 9.3 0.2 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) ETF PF01012.21 EMT52913.1 - 2.4e-44 151.4 3.2 3.2e-44 151.0 3.2 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EMT52913.1 - 6.2e-36 122.3 0.3 1.3e-35 121.3 0.3 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain FbpC_C_terminal PF17845.1 EMT52913.1 - 0.028 14.5 0.5 0.97 9.6 0.1 2.9 3 0 0 3 3 3 0 FbpC C-terminal regulatory nucleotide binding domain ETF PF01012.21 EMT52914.1 - 7.4e-53 179.1 0.4 9.3e-53 178.8 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Usp PF00582.26 EMT52914.1 - 0.016 15.7 0.1 0.14 12.7 0.1 2.2 1 1 0 1 1 1 0 Universal stress protein family ECH_1 PF00378.20 EMT52915.1 - 4.5e-71 239.1 0.0 5.1e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMT52915.1 - 3.2e-38 132.1 0.0 1.5e-33 116.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase TetR_C_4 PF08359.11 EMT52916.1 - 5.8e-49 165.6 0.8 8.9e-49 165.0 0.8 1.3 1 0 0 1 1 1 1 YsiA-like protein, C-terminal region TetR_N PF00440.23 EMT52916.1 - 9.1e-18 63.8 0.1 1.9e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EMT52916.1 - 3.9e-12 46.5 1.0 1e-11 45.1 0.3 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 EMT52916.1 - 7.4e-05 22.8 0.2 0.00014 22.0 0.2 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain EURL PF06937.11 EMT52916.1 - 0.0019 17.6 0.1 0.0022 17.5 0.1 1.1 1 0 0 1 1 1 1 EURL protein TetR_C_27 PF17935.1 EMT52916.1 - 0.0032 17.5 0.2 0.0092 16.0 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_2 PF08361.11 EMT52916.1 - 0.0038 17.3 0.1 0.0068 16.5 0.1 1.5 1 1 0 1 1 1 1 MAATS-type transcriptional repressor, C-terminal region TetR_C_5 PF08360.11 EMT52916.1 - 0.043 14.0 0.5 0.4 10.9 0.1 2.1 2 0 0 2 2 2 0 QacR-like protein, C-terminal region TetR_C_11 PF16859.5 EMT52916.1 - 0.074 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AMP-binding PF00501.28 EMT52917.1 - 4.8e-112 374.6 0.0 5.8e-112 374.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMT52917.1 - 1.1e-22 80.7 0.8 2.4e-22 79.7 0.8 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 EMT52917.1 - 0.13 12.6 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain LytR_cpsA_psr PF03816.14 EMT52918.1 - 2.6e-45 154.3 0.0 3.6e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain Thiolase_N PF00108.23 EMT52920.1 - 4.9e-89 298.1 0.3 7.2e-89 297.6 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMT52920.1 - 3.3e-47 159.2 0.1 3.3e-47 159.2 0.1 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMT52920.1 - 1.6e-07 31.1 0.1 5e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PrmA PF06325.13 EMT52921.1 - 2.5e-41 142.0 0.1 2.5e-41 142.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EMT52921.1 - 2.7e-07 30.3 0.0 4.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EMT52921.1 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EMT52921.1 - 4.2e-06 26.7 0.0 7.5e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 EMT52921.1 - 5.9e-06 26.2 0.0 1.3e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT52921.1 - 8.9e-06 25.6 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT52921.1 - 1.4e-05 25.7 0.0 2.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT52921.1 - 0.0016 19.0 0.0 0.0031 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMT52921.1 - 0.0026 17.6 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EMT52921.1 - 0.019 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 EMT52921.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 EMT52921.1 - 0.036 13.7 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GCD14 PF08704.10 EMT52921.1 - 0.044 13.5 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_12 PF08242.12 EMT52921.1 - 0.1 13.4 0.0 0.24 12.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EMT52921.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PS_pyruv_trans PF04230.13 EMT52922.1 - 3.8e-46 158.3 0.0 4.6e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase Methyltransf_11 PF08241.12 EMT52923.1 - 1.8e-23 83.0 0.0 3e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT52923.1 - 1.8e-20 73.4 0.0 3.2e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT52923.1 - 1.8e-17 63.5 0.0 2.3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT52923.1 - 4.7e-16 59.1 0.0 6.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT52923.1 - 2.2e-13 50.1 0.0 3.1e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMT52923.1 - 1e-11 45.4 0.0 1.7e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EMT52923.1 - 1.1e-05 24.5 0.0 1.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 EMT52923.1 - 2.2e-05 24.1 0.0 4.8e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 EMT52923.1 - 3.2e-05 22.7 0.0 4.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 EMT52923.1 - 4.9e-05 22.8 0.0 6.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase N6_N4_Mtase PF01555.18 EMT52923.1 - 0.00035 20.4 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 2 DNA methylase Methyltransf_24 PF13578.6 EMT52923.1 - 0.00044 21.2 0.0 0.00072 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMT52923.1 - 0.00056 19.7 0.0 0.00085 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 EMT52923.1 - 0.00081 19.3 0.0 0.0047 16.8 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 EMT52923.1 - 0.0036 16.9 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Phage_TTP_13 PF16463.5 EMT52923.1 - 0.0041 16.7 0.0 0.0084 15.6 0.0 1.5 1 0 0 1 1 1 1 Phage tail tube protein family UPF0020 PF01170.18 EMT52923.1 - 0.045 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 EMT52923.1 - 0.048 13.7 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EMT52923.1 - 0.074 12.4 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.16 EMT52923.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme HTH_44 PF14641.6 EMT52923.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 Methyltransf_15 PF09445.10 EMT52923.1 - 0.16 11.5 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GyrI-like PF06445.15 EMT52924.1 - 2.4e-27 96.1 0.0 3.2e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 EMT52924.1 - 2.8e-20 73.0 0.0 4.7e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Integron-associated effector binding protein HTH_18 PF12833.7 EMT52924.1 - 6.1e-18 64.9 0.4 9.3e-18 64.3 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EMT52924.1 - 1.6e-14 53.6 0.0 1.3e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_10 PF04967.12 EMT52924.1 - 0.12 12.2 0.0 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 HTH DNA binding domain Polysacc_synt PF01943.17 EMT52925.1 - 1.1e-36 126.7 25.1 1.6e-36 126.1 15.4 2.3 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 EMT52925.1 - 5.5e-22 78.4 18.6 5.5e-22 78.4 18.6 4.3 3 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Polysacc_synt_3 PF13440.6 EMT52925.1 - 9.2e-08 31.6 6.2 9.2e-08 31.6 6.2 3.9 2 1 2 4 4 4 1 Polysaccharide biosynthesis protein MurJ PF03023.14 EMT52925.1 - 1.9e-06 26.8 21.5 1.9e-06 26.8 21.5 1.7 1 1 1 2 2 2 1 Lipid II flippase MurJ MatE PF01554.18 EMT52925.1 - 3.4e-06 26.8 31.1 2.2e-05 24.2 8.9 4.3 3 2 0 4 4 4 2 MatE AMP-binding PF00501.28 EMT52926.1 - 0.00032 19.4 0.0 0.00057 18.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme MurJ PF03023.14 EMT52927.1 - 3.5e-83 279.7 26.6 4.6e-83 279.3 26.6 1.1 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 EMT52927.1 - 4.6e-24 85.1 33.9 3.1e-14 53.3 19.4 4.2 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 EMT52927.1 - 4.7e-11 42.6 26.3 4.4e-08 32.9 1.9 4.9 2 2 3 5 5 5 3 MatE Polysacc_synt_3 PF13440.6 EMT52927.1 - 1e-10 41.4 6.1 4.1e-07 29.5 0.8 2.7 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Wzy_C PF04932.15 EMT52928.1 - 5e-11 42.5 8.7 5e-11 42.5 8.7 4.2 1 1 2 4 4 4 2 O-Antigen ligase VCBS PF13517.6 EMT52929.1 - 2.3e-06 28.1 3.6 0.088 13.4 1.5 3.9 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EMT52929.1 - 0.00035 20.6 4.6 0.4 10.8 0.2 3.5 3 0 0 3 3 3 2 FG-GAP repeat Itfg2 PF15907.5 EMT52929.1 - 0.036 13.1 0.0 10 5.0 0.0 3.1 3 0 0 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 Peripla_BP_7 PF18610.1 EMT52929.1 - 0.063 13.4 0.0 0.97 9.6 0.0 2.4 2 0 0 2 2 2 0 Periplasmic binding protein domain TrbC PF04956.13 EMT52929.1 - 0.55 10.5 5.4 1.5 9.1 5.4 1.8 1 0 0 1 1 1 0 TrbC/VIRB2 family PrgI PF12666.7 EMT52929.1 - 8.1 7.2 11.0 4.2 8.1 0.8 2.9 2 1 0 3 3 3 0 PrgI family protein MFS_1_like PF12832.7 EMT52931.1 - 8.9e-57 192.7 29.9 1.2e-56 192.2 29.9 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EMT52931.1 - 1.7e-18 66.7 59.1 1.4e-15 57.1 37.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 EMT52931.1 - 1.4e-15 57.0 19.5 8e-14 51.2 9.3 2.0 2 0 0 2 2 2 2 LacY proton/sugar symporter Nuc_H_symport PF03825.16 EMT52931.1 - 2.9e-14 52.9 28.0 3.6e-14 52.6 28.0 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter Transgly_assoc PF04226.13 EMT52931.1 - 0.022 15.0 5.1 0.022 15.0 5.1 3.4 3 0 0 3 3 3 0 Transglycosylase associated protein MFS_4 PF06779.14 EMT52931.1 - 0.031 13.6 26.8 0.048 13.0 25.5 1.8 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB DUF3487 PF11990.8 EMT52931.1 - 8.9 6.2 8.8 17 5.3 1.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3487) Glyco_trans_4_4 PF13579.6 EMT52932.1 - 1.4e-12 48.3 0.2 2.5e-12 47.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EMT52932.1 - 5.3e-11 42.8 0.1 1.3e-09 38.3 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EMT52932.1 - 7.7e-10 38.6 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT52932.1 - 4.3e-07 30.4 0.0 8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EMT52933.1 - 2.9e-40 137.6 0.0 1.3e-39 135.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT52933.1 - 1.7e-30 106.2 0.1 6.1e-30 104.4 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT52933.1 - 8.5e-28 97.5 0.7 2e-27 96.2 0.3 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EMT52933.1 - 4.5e-22 79.2 0.4 4.5e-22 79.2 0.4 2.1 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EMT52933.1 - 4.4e-11 43.0 0.0 9.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EMT52933.1 - 1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Peptidase_M55 PF04951.13 EMT52934.1 - 9.8e-94 313.6 0.1 1.1e-93 313.5 0.1 1.0 1 0 0 1 1 1 1 D-aminopeptidase UDPG_MGDP_dh_N PF03721.14 EMT52935.1 - 4.2e-40 137.3 0.0 1e-39 136.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EMT52935.1 - 3.2e-22 78.5 0.0 8.9e-22 77.1 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EMT52935.1 - 3.1e-19 69.4 0.3 7.8e-19 68.0 0.1 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 EMT52935.1 - 2.5e-06 27.8 0.3 9e-05 22.7 0.1 2.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EMT52935.1 - 4e-06 26.8 1.2 2.4e-05 24.3 0.1 2.5 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMT52935.1 - 0.0055 16.0 0.5 0.028 13.7 0.2 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EMT52935.1 - 0.023 14.0 0.1 3.9 6.8 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EMT52935.1 - 0.027 13.7 0.1 0.049 12.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_11 PF14833.6 EMT52935.1 - 0.044 14.0 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Fer2 PF00111.27 EMT52936.1 - 6.7e-09 35.6 0.0 8.8e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 EMT52936.1 - 0.2 11.5 0.3 0.2 11.5 0.3 2.0 3 0 0 3 3 3 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B DUF350 PF03994.14 EMT52937.1 - 4.7e-25 87.5 3.0 2.2e-12 46.9 0.3 2.1 2 0 0 2 2 2 2 Domain of Unknown Function (DUF350) CrgA PF06781.12 EMT52937.1 - 0.095 12.8 4.5 2.3 8.3 0.3 2.2 2 0 0 2 2 2 0 Cell division protein CrgA CbtA PF09490.10 EMT52937.1 - 0.9 9.3 4.6 0.27 11.0 0.8 1.9 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtA) CoA_binding_3 PF13727.6 EMT52937.1 - 1 9.4 4.5 7 6.6 0.8 2.2 1 1 1 2 2 2 0 CoA-binding domain MutS_V PF00488.21 EMT52938.1 - 1.2e-35 123.2 0.1 2.3e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V Smr PF01713.21 EMT52938.1 - 8.4e-20 70.9 0.8 8.4e-20 70.9 0.8 2.4 2 0 0 2 2 2 1 Smr domain MutS_III PF05192.18 EMT52938.1 - 0.0031 17.8 0.6 0.0031 17.8 0.6 2.7 2 1 0 2 2 2 1 MutS domain III ERM PF00769.19 EMT52938.1 - 0.0078 16.1 23.7 0.0078 16.1 23.7 2.8 2 1 0 2 2 2 1 Ezrin/radixin/moesin family Exonuc_VII_L PF02601.15 EMT52938.1 - 0.01 15.5 9.7 0.062 12.9 5.1 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Imm26 PF15428.6 EMT52938.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 26 zf-C4H2 PF10146.9 EMT52938.1 - 0.38 11.0 11.1 2.2 8.5 5.7 2.5 2 0 0 2 2 2 0 Zinc finger-containing protein GBP_C PF02841.14 EMT52938.1 - 2.3 7.6 17.7 6.6 6.0 17.7 1.8 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Phage_holin_4_2 PF04020.13 EMT52939.1 - 2.4e-14 53.9 18.1 2.8e-14 53.7 18.1 1.1 1 0 0 1 1 1 1 Mycobacterial 4 TMS phage holin, superfamily IV DUF2512 PF10710.9 EMT52939.1 - 0.011 15.4 8.9 0.015 14.9 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) DUF4229 PF14012.6 EMT52939.1 - 0.036 14.2 21.6 0.071 13.2 8.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) UPF0767 PF15990.5 EMT52939.1 - 0.11 12.6 1.8 0.21 11.8 0.1 2.1 1 1 1 2 2 2 0 UPF0767 family EcsB PF05975.12 EMT52939.1 - 0.13 11.1 11.2 0.14 11.0 11.2 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB DUF5455 PF17537.2 EMT52939.1 - 0.2 12.1 21.3 0.11 13.0 6.7 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5455) ThrE PF06738.12 EMT52939.1 - 0.92 8.8 16.5 2.2 7.6 4.7 2.0 1 1 1 2 2 2 0 Putative threonine/serine exporter DUF2427 PF10348.9 EMT52939.1 - 1.1 9.1 9.2 1.5 8.6 9.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) TcpE PF12648.7 EMT52939.1 - 1.7 9.2 11.4 0.26 11.9 7.0 1.7 1 1 1 2 2 2 0 TcpE family Bac_export_2 PF01312.19 EMT52939.1 - 3.1 6.9 6.8 1.1 8.4 4.2 1.4 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family Trep_Strep PF09605.10 EMT52939.1 - 5.9 6.8 17.6 7.6 6.5 17.6 1.2 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF5313 PF17240.2 EMT52939.1 - 6.1 7.3 8.5 0.4 11.1 2.7 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5313) AIRC PF00731.20 EMT52940.1 - 1e-18 67.3 3.3 2.9e-18 65.8 3.4 1.7 2 0 0 2 2 2 1 AIR carboxylase Sigma54_activ_2 PF14532.6 EMT52940.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain NAD_synthase PF02540.17 EMT52941.1 - 1.5e-05 24.2 0.0 3.9e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.21 EMT52941.1 - 4.8e-05 23.2 0.3 9.2e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Asparagine synthase ATP_bind_3 PF01171.20 EMT52941.1 - 0.00019 21.3 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 PP-loop family QueC PF06508.13 EMT52941.1 - 0.00023 20.7 0.0 0.00062 19.3 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EMT52941.1 - 0.11 11.3 0.0 0.65 8.7 0.0 2.0 2 0 0 2 2 2 0 tRNA methyl transferase LigT_PEase PF02834.16 EMT52941.1 - 0.12 12.6 0.5 1.6 8.9 0.0 2.8 3 0 0 3 3 3 0 LigT like Phosphoesterase Arginosuc_synth PF00764.19 EMT52941.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ZapA PF05164.13 EMT52942.1 - 1.7e-16 60.4 0.2 1.9e-16 60.2 0.2 1.1 1 0 0 1 1 1 1 Cell division protein ZapA tRNA_synthFbeta PF17759.1 EMT52943.1 - 5.4e-65 218.8 0.0 8.3e-65 218.2 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 EMT52943.1 - 7.6e-65 217.8 0.0 1.5e-64 216.8 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain FDX-ACB PF03147.14 EMT52943.1 - 1.5e-30 105.5 0.1 3.7e-30 104.2 0.1 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA_bind PF01588.20 EMT52943.1 - 8.2e-26 90.0 0.5 1.7e-25 89.0 0.5 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain B5 PF03484.15 EMT52943.1 - 7.3e-20 71.0 0.0 3.6e-19 68.8 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 EMT52944.1 - 1.3e-107 358.9 0.0 1.6e-107 358.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 EMT52944.1 - 3.8e-27 94.0 2.6 3.8e-27 94.0 2.6 1.7 2 0 0 2 2 2 1 Aminoacyl tRNA synthetase class II, N-terminal domain DUF2225 PF09986.9 EMT52945.1 - 2.9e-58 197.1 2.5 3.5e-58 196.9 2.5 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_12 PF13424.6 EMT52945.1 - 0.0013 19.0 8.7 0.0021 18.3 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMT52945.1 - 0.0016 18.2 0.0 0.0016 18.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMT52945.1 - 0.023 14.8 0.1 0.023 14.8 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat zinc_ribbon_9 PF14369.6 EMT52945.1 - 0.028 14.7 0.1 6 7.2 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon TPR_8 PF13181.6 EMT52945.1 - 0.044 14.0 0.0 0.044 14.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EMT52945.1 - 0.054 13.0 0.2 3.6 7.1 0.0 2.5 2 0 0 2 2 2 0 SHNi-TPR TPR_6 PF13174.6 EMT52945.1 - 0.1 13.3 0.2 0.1 13.3 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-BED PF02892.15 EMT52945.1 - 0.12 12.5 0.2 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger TPR_7 PF13176.6 EMT52945.1 - 0.12 12.5 0.2 0.12 12.5 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 EMT52945.1 - 0.46 11.5 2.6 31 5.7 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger SpoU_methylase PF00588.19 EMT52946.1 - 7.3e-39 133.2 0.0 3.1e-38 131.2 0.0 1.8 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EMT52946.1 - 9.4e-14 51.5 0.6 1.6e-12 47.5 0.0 2.9 3 0 0 3 3 3 1 RNA 2'-O ribose methyltransferase substrate binding TSNR_N PF04705.12 EMT52946.1 - 1.9e-06 27.9 0.1 7e-06 26.1 0.1 1.8 2 0 0 2 2 2 1 Thiostrepton-resistance methylase, N terminus SRP54 PF00448.22 EMT52946.1 - 0.071 12.7 0.0 0.39 10.3 0.0 2.1 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain TrkA_N PF02254.18 EMT52947.1 - 5.9e-31 107.1 1.5 1.4e-30 105.9 1.5 1.6 1 0 0 1 1 1 1 TrkA-N domain TrkA_C PF02080.21 EMT52947.1 - 1.2e-17 63.5 1.1 4.2e-16 58.5 0.1 2.5 2 0 0 2 2 2 1 TrkA-C domain NAD_binding_2 PF03446.15 EMT52947.1 - 9e-06 25.9 0.5 2.2e-05 24.7 0.5 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EMT52947.1 - 0.0001 21.7 0.1 0.00017 21.0 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EMT52947.1 - 0.00017 21.5 1.9 0.21 11.6 0.2 2.5 1 1 2 3 3 3 2 Zinc-binding dehydrogenase Epimerase PF01370.21 EMT52947.1 - 0.00082 18.9 0.1 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EMT52947.1 - 0.00087 19.2 0.3 0.0016 18.3 0.3 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EMT52947.1 - 0.00093 19.2 0.2 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EMT52947.1 - 0.00094 19.7 1.7 0.0024 18.4 0.2 2.4 2 2 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding_2 PF13380.6 EMT52947.1 - 0.005 17.3 0.4 0.023 15.2 0.1 2.0 1 1 1 2 2 2 1 CoA binding domain PglD_N PF17836.1 EMT52947.1 - 0.006 17.2 2.3 0.019 15.6 0.2 2.6 2 1 0 2 2 2 1 PglD N-terminal domain AlaDh_PNT_C PF01262.21 EMT52947.1 - 0.0064 15.8 1.3 0.01 15.1 0.7 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Castor_Poll_mid PF06241.12 EMT52947.1 - 0.0066 16.4 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Castor and Pollux, part of voltage-gated ion channel Shikimate_DH PF01488.20 EMT52947.1 - 0.0071 16.4 1.0 0.018 15.1 0.3 2.0 1 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EMT52947.1 - 0.017 15.4 0.2 0.031 14.5 0.2 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Gp_dh_N PF00044.24 EMT52947.1 - 0.024 15.0 1.3 0.04 14.2 0.4 2.0 2 1 0 2 2 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain XdhC_C PF13478.6 EMT52947.1 - 0.03 14.8 0.1 0.07 13.6 0.0 1.8 1 1 0 1 1 1 0 XdhC Rossmann domain Phycobilisome PF00502.19 EMT52947.1 - 0.034 14.1 0.1 0.052 13.5 0.1 1.2 1 0 0 1 1 1 0 Phycobilisome protein IlvN PF07991.12 EMT52947.1 - 0.05 13.2 1.6 0.33 10.5 0.5 2.3 1 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 EMT52947.1 - 0.083 12.5 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EMT52947.1 - 0.11 12.9 0.5 0.21 12.1 0.2 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Rossmann-like PF10727.9 EMT52947.1 - 0.41 10.5 2.1 8.7 6.2 0.6 2.5 2 1 0 2 2 2 0 Rossmann-like domain SSPI PF14098.6 EMT52948.1 - 1.3e-26 92.5 0.0 1.5e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Small, acid-soluble spore protein I DUF1904 PF08921.11 EMT52948.1 - 0.034 14.4 0.0 0.064 13.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1904) Spore_GerAC PF05504.11 EMT52949.1 - 2.9e-25 89.4 0.0 5e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal Beta-lactamase2 PF13354.6 EMT52949.1 - 0.0016 18.1 0.0 0.027 14.1 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase enzyme family Spore_permease PF03845.13 EMT52950.1 - 1e-58 198.7 39.7 1.4e-58 198.2 39.7 1.3 1 0 0 1 1 1 1 Spore germination protein Trp_Tyr_perm PF03222.13 EMT52950.1 - 0.084 11.9 28.8 0.13 11.2 28.8 1.2 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family PspB PF06667.12 EMT52950.1 - 3.2 7.9 5.3 4.4 7.4 0.0 3.2 2 1 0 2 2 2 0 Phage shock protein B GerA PF03323.13 EMT52951.1 - 4.3e-188 625.5 6.2 5e-188 625.3 6.2 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein DUF417 PF04224.12 EMT52951.1 - 2 8.0 5.8 4.3 6.9 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF417 DUF1294 PF06961.13 EMT52952.1 - 5.5e-21 74.6 0.3 5.5e-21 74.6 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1294) DUF3784 PF12650.7 EMT52952.1 - 0.056 13.7 3.6 0.17 12.1 3.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) RseC_MucC PF04246.12 EMT52952.1 - 0.22 11.5 3.8 1.8 8.5 0.1 2.4 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SNARE_assoc PF09335.11 EMT52953.1 - 2.9e-17 63.3 7.5 2.9e-17 63.3 7.5 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein Pam17 PF08566.10 EMT52953.1 - 0.075 12.9 0.8 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF502 PF04367.13 EMT52953.1 - 0.52 10.2 4.5 2.9 7.8 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF502) DUF1279 PF06916.13 EMT52953.1 - 1.5 9.4 5.5 43 4.8 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1279) DUF4080 PF13311.6 EMT52954.1 - 3.6e-45 154.5 1.3 3.6e-45 154.5 1.3 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4080) B12-binding PF02310.19 EMT52954.1 - 2.2e-16 60.0 0.0 5.3e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain Radical_SAM PF04055.21 EMT52954.1 - 9e-15 55.4 0.1 7.4e-14 52.5 0.0 2.4 2 1 0 2 2 2 1 Radical SAM superfamily Sec7_N PF12783.7 EMT52954.1 - 0.006 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Yop-YscD_ppl PF16693.5 EMT52954.1 - 0.098 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain MULE PF10551.9 EMT52954.1 - 0.14 12.6 0.1 0.37 11.2 0.1 1.7 1 0 0 1 1 1 0 MULE transposase domain MoCF_biosynth PF00994.24 EMT52955.1 - 4.9e-31 107.3 0.2 5.6e-31 107.1 0.2 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ligase_CoA PF00549.19 EMT52955.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 CoA-ligase Aminotran_1_2 PF00155.21 EMT52956.1 - 1.7e-13 50.5 0.0 2.1e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EMT52956.1 - 2.7e-08 33.4 0.0 9.1e-08 31.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family UBA_4 PF14555.6 EMT52956.1 - 0.0023 17.7 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 2 UBA-like domain Rrf2 PF02082.20 EMT52956.1 - 0.037 14.4 0.0 0.1 13.0 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator PT-VENN PF04829.13 EMT52956.1 - 0.22 11.6 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif TrkH PF02386.16 EMT52957.1 - 2.9e-60 204.2 27.5 1.2e-59 202.1 27.5 1.7 1 1 0 1 1 1 1 Cation transport protein SSF PF00474.17 EMT52958.1 - 1.2e-13 50.7 35.4 5.7e-09 35.3 20.6 2.3 2 0 0 2 2 2 2 Sodium:solute symporter family Iso_dh PF00180.20 EMT52959.1 - 1.4e-136 455.3 0.0 1.5e-136 455.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HMGL-like PF00682.19 EMT52960.1 - 1e-97 326.9 4.7 1.4e-97 326.4 4.7 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EMT52960.1 - 1.3e-35 122.2 2.4 1.5e-35 122.0 0.4 2.0 2 0 0 2 2 2 1 LeuA allosteric (dimerisation) domain IlvN PF07991.12 EMT52961.1 - 4.5e-78 260.5 0.9 6e-78 260.1 0.9 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EMT52961.1 - 5.5e-68 227.8 0.2 9.8e-68 227.0 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 EMT52961.1 - 2.3e-10 40.1 0.0 3.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EMT52961.1 - 4e-08 33.5 0.1 1e-07 32.2 0.1 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 EMT52961.1 - 1.1e-07 32.2 0.0 2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EMT52961.1 - 2.8e-07 31.0 0.2 7.3e-07 29.7 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding_2 PF13380.6 EMT52961.1 - 0.0032 17.9 0.1 0.0069 16.9 0.1 1.6 1 1 0 1 1 1 1 CoA binding domain ApbA PF02558.16 EMT52961.1 - 0.011 15.3 0.1 0.025 14.2 0.1 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Oxidored_nitro PF00148.19 EMT52961.1 - 0.02 13.7 0.1 0.042 12.6 0.0 1.6 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase TrkA_N PF02254.18 EMT52961.1 - 0.06 13.6 0.1 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 EMT52961.1 - 0.069 13.6 0.2 0.15 12.5 0.2 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding MukF_M PF17192.4 EMT52961.1 - 0.11 12.2 0.0 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 MukF middle domain CoA_binding PF02629.19 EMT52961.1 - 0.13 13.0 0.1 0.54 11.0 0.0 2.1 2 0 0 2 2 2 0 CoA binding domain ALS_ss_C PF10369.9 EMT52962.1 - 2.6e-30 104.4 0.3 7.1e-28 96.6 0.0 2.2 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT_5 PF13710.6 EMT52962.1 - 2.7e-17 62.4 0.0 7.8e-17 60.9 0.0 1.7 2 0 0 2 2 2 1 ACT domain ACT PF01842.25 EMT52962.1 - 8.6e-15 54.2 0.0 1.6e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 EMT52962.1 - 3.9e-05 24.2 0.1 9.6e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 ACT domain NIL PF09383.10 EMT52962.1 - 0.0083 15.9 0.1 5.2 7.0 0.0 2.4 2 0 0 2 2 2 2 NIL domain TPP_enzyme_N PF02776.18 EMT52963.1 - 9e-55 184.9 0.3 5.1e-54 182.5 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMT52963.1 - 1.6e-54 183.9 0.5 3.1e-53 179.7 0.1 2.9 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMT52963.1 - 1.3e-47 160.9 0.1 2.6e-47 160.0 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EMT52963.1 - 0.02 14.6 0.1 0.049 13.4 0.1 1.6 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ATP-sulfurylase PF01747.17 EMT52965.1 - 1.5e-94 315.4 0.0 1.9e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EMT52965.1 - 1.9e-48 164.2 0.0 2.9e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain PAPS_reduct PF01507.19 EMT52966.1 - 6.6e-50 169.5 0.0 8.2e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family AglB_L1 PF18079.1 EMT52968.1 - 2.6e-06 27.6 0.0 0.067 13.5 0.0 2.7 2 0 0 2 2 2 2 Archaeal glycosylation protein B long peripheral domain LPAM_1 PF08139.12 EMT52968.1 - 0.053 14.0 1.8 0.087 13.4 1.8 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF4684 PF15736.5 EMT52968.1 - 0.18 10.5 0.1 0.23 10.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) Y_phosphatase3 PF13350.6 EMT52969.1 - 6.1e-12 46.0 0.5 6.9e-12 45.8 0.5 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family GerE PF00196.19 EMT52970.1 - 2.7e-14 52.4 0.3 4.3e-14 51.8 0.3 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 EMT52970.1 - 0.0026 17.3 0.1 0.0046 16.5 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 EMT52970.1 - 0.014 15.4 0.1 0.038 14.0 0.0 1.7 1 1 0 1 1 1 0 Winged helix-turn helix GAF_2 PF13185.6 EMT52970.1 - 0.025 14.9 0.0 0.073 13.4 0.0 1.8 1 1 1 2 2 2 0 GAF domain HTH_10 PF04967.12 EMT52970.1 - 0.031 14.1 0.4 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain HTH_28 PF13518.6 EMT52970.1 - 0.072 13.2 0.7 0.2 11.8 0.0 2.0 2 1 1 3 3 3 0 Helix-turn-helix domain 2CSK_N PF08521.10 EMT52970.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal Ribosomal_L20 PF00453.18 EMT52971.1 - 2.2e-48 162.8 5.8 2.5e-48 162.6 5.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 Ribosomal_L35p PF01632.19 EMT52972.1 - 4.9e-26 91.0 9.3 5.3e-26 90.9 9.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 IF3_C PF00707.22 EMT52973.1 - 1.5e-37 127.4 0.6 2.3e-37 126.8 0.6 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 EMT52973.1 - 2.5e-34 117.4 0.9 3.6e-34 116.9 0.1 1.7 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain DUF2813 PF11398.8 EMT52973.1 - 0.026 13.8 0.2 0.031 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Snurportin1 PF11538.8 EMT52973.1 - 1.5 9.0 5.5 0.61 10.3 2.1 2.0 2 0 0 2 2 2 0 Snurportin1 Mob_synth_C PF06463.13 EMT52974.1 - 6.9e-37 126.2 0.0 1e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EMT52974.1 - 2.7e-34 119.0 0.0 4.1e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EMT52974.1 - 1.6e-10 41.4 0.0 3.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EMT52974.1 - 8.6e-09 35.6 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain PBP_like PF12727.7 EMT52975.1 - 1.2e-64 217.0 0.0 3.9e-64 215.3 0.0 1.8 2 0 0 2 2 2 1 PBP superfamily domain MoeA_N PF03453.17 EMT52975.1 - 1.2e-39 135.6 0.5 2e-39 134.9 0.5 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EMT52975.1 - 3.5e-23 81.8 0.0 8.7e-23 80.6 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain MoeA_C PF03454.15 EMT52975.1 - 3.3e-09 36.8 0.1 1.1e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Phosphonate-bd PF12974.7 EMT52975.1 - 0.00097 18.8 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_11 PF13531.6 EMT52975.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein MoeA_N PF03453.17 EMT52976.1 - 7.7e-40 136.2 0.2 1.3e-39 135.5 0.2 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EMT52976.1 - 5.7e-24 84.4 0.1 1.1e-23 83.5 0.1 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 EMT52976.1 - 7.1e-18 64.6 1.2 5.2e-16 58.6 0.1 3.5 4 0 0 4 4 4 1 MoeA C-terminal region (domain IV) ThiS PF02597.20 EMT52977.1 - 1.6e-14 54.3 0.1 1.8e-14 54.1 0.1 1.0 1 0 0 1 1 1 1 ThiS family Urm1 PF09138.11 EMT52977.1 - 0.0062 16.9 0.0 0.0068 16.7 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) AFOR_C PF01314.18 EMT52979.1 - 5.3e-126 420.7 1.6 7.4e-126 420.2 1.6 1.2 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 EMT52979.1 - 1.5e-74 250.2 0.4 2.4e-74 249.5 0.4 1.3 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain Molybdop_Fe4S4 PF04879.16 EMT52979.1 - 0.02 14.9 0.6 0.32 11.0 0.3 2.7 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain PBP_like PF12727.7 EMT52980.1 - 1.2e-57 194.1 0.0 1.7e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 PBP superfamily domain HTH_17 PF12728.7 EMT52980.1 - 8.7e-17 61.1 0.1 1.8e-16 60.1 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_22 PF13309.6 EMT52980.1 - 0.043 13.9 0.1 0.091 12.9 0.1 1.6 1 0 0 1 1 1 0 HTH domain HTH_23 PF13384.6 EMT52980.1 - 0.12 12.2 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Peptidase_S66 PF02016.15 EMT52980.1 - 0.18 11.9 0.0 0.53 10.4 0.0 1.8 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain PBP_like_2 PF12849.7 EMT52981.1 - 9.4e-30 104.2 2.6 1.2e-29 103.9 2.6 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 EMT52981.1 - 1e-11 45.0 0.1 1e-10 41.8 0.1 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT52981.1 - 7.5e-07 29.4 2.4 0.007 16.4 0.0 2.3 1 1 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EMT52981.1 - 1.5e-05 24.6 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EMT52981.1 - 2.8e-05 24.1 6.6 0.00043 20.2 3.4 2.3 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 EMT52981.1 - 0.0027 16.8 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 PBP superfamily domain LysR_substrate PF03466.20 EMT52981.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.5 1 1 0 1 1 1 0 LysR substrate binding domain LPAM_1 PF08139.12 EMT52981.1 - 0.083 13.4 2.4 0.17 12.5 2.4 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site BPD_transp_1 PF00528.22 EMT52982.1 - 2.1e-14 53.7 13.2 2.9e-14 53.2 13.2 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EMT52983.1 - 8.6e-29 100.8 0.0 1.3e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT52983.1 - 5.8e-13 49.3 0.6 2.9e-06 27.3 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT52983.1 - 2.8e-08 33.5 0.0 5.4e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT52983.1 - 4.8e-06 26.9 0.2 3e-05 24.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT52983.1 - 3e-05 23.7 0.0 6.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT52983.1 - 0.0001 22.9 0.0 0.00018 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT52983.1 - 0.0017 18.8 0.2 0.0033 17.8 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EMT52983.1 - 0.0036 17.1 0.1 0.0098 15.6 0.1 1.9 1 1 1 2 2 2 1 AAA domain cobW PF02492.19 EMT52983.1 - 0.0086 15.7 0.1 0.058 13.0 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EMT52983.1 - 0.0097 16.0 0.1 0.034 14.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EMT52983.1 - 0.012 15.4 0.1 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EMT52983.1 - 0.018 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 EMT52983.1 - 0.018 15.2 0.3 0.031 14.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EMT52983.1 - 0.027 14.4 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 EMT52983.1 - 0.036 14.3 0.1 0.65 10.3 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 EMT52983.1 - 0.075 13.3 0.2 0.94 9.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 EMT52983.1 - 0.077 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 EMT52983.1 - 0.091 12.5 0.2 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EMT52983.1 - 0.11 12.3 0.1 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 EMT52983.1 - 0.17 11.9 0.1 0.81 9.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 EMT52983.1 - 0.19 10.5 0.0 0.53 9.0 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein Rad17 PF03215.15 EMT52983.1 - 0.19 11.6 0.1 0.39 10.6 0.0 1.5 2 0 0 2 2 1 0 Rad17 P-loop domain NB-ARC PF00931.22 EMT52983.1 - 0.21 10.7 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ThiF PF00899.21 EMT52984.1 - 1.1e-60 205.1 0.0 2.2e-60 204.0 0.0 1.4 2 0 0 2 2 2 1 ThiF family ApbA PF02558.16 EMT52984.1 - 0.002 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EMT52984.1 - 0.003 17.6 0.2 0.0079 16.3 0.1 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase E1-N PF14463.6 EMT52984.1 - 0.0055 16.5 0.5 0.55 10.0 0.2 3.3 3 1 1 4 4 4 1 E1 N-terminal domain Pyr_redox_2 PF07992.14 EMT52984.1 - 0.021 14.0 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMT52984.1 - 0.026 14.5 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding KR PF08659.10 EMT52984.1 - 0.043 13.7 0.1 0.074 13.0 0.1 1.3 1 0 0 1 1 1 0 KR domain NAD_Gly3P_dh_N PF01210.23 EMT52984.1 - 0.09 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 EMT52984.1 - 0.11 12.4 1.0 0.2 11.5 1.0 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EMT52984.1 - 0.11 11.7 0.0 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 EMT52984.1 - 0.14 12.6 0.2 0.85 10.1 0.1 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding tRNA-synt_2b PF00587.25 EMT52985.1 - 1.4e-40 139.2 0.0 2.7e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EMT52985.1 - 6.8e-24 83.9 1.9 2.1e-23 82.3 1.9 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EMT52985.1 - 1.3e-15 57.2 0.0 2.6e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EMT52985.1 - 2e-15 56.6 0.2 8.3e-15 54.6 0.1 2.2 2 0 0 2 2 2 1 TGS domain YtxC PF08812.11 EMT52986.1 - 6.2e-50 169.8 0.6 7.9e-50 169.5 0.6 1.1 1 0 0 1 1 1 1 YtxC-like family PAH PF02671.21 EMT52986.1 - 0.32 11.2 5.0 0.52 10.5 0.6 3.1 2 2 0 2 2 2 0 Paired amphipathic helix repeat CBM46 PF18448.1 EMT52987.1 - 0.1 12.9 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain Coat_F PF07875.12 EMT52988.1 - 5.3e-19 68.2 0.5 1.4e-18 66.9 0.1 1.9 2 0 0 2 2 2 1 Coat F domain SNARE_assoc PF09335.11 EMT52989.1 - 9.3e-14 52.0 2.2 9.3e-14 52.0 2.2 1.8 1 1 1 2 2 2 1 SNARE associated Golgi protein FixQ PF05545.11 EMT52989.1 - 0.014 15.4 0.7 5.5 7.0 0.0 2.8 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ ThiW PF09512.10 EMT52989.1 - 0.038 14.1 6.5 0.2 11.7 1.3 2.1 1 1 1 2 2 2 0 Thiamine-precursor transporter protein (ThiW) Hydrolase_2 PF07486.12 EMT52990.1 - 4.4e-17 62.8 0.0 5.3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Cell Wall Hydrolase Spore_GerQ PF09671.10 EMT52991.1 - 5.1e-38 129.0 0.4 7.2e-38 128.5 0.4 1.2 1 0 0 1 1 1 1 Spore coat protein (Spore_GerQ) PilZ PF07238.14 EMT52992.1 - 1.2e-08 35.2 0.0 1.6e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 PilZ domain Acetyltransf_9 PF13527.7 EMT52993.1 - 8.1e-26 90.6 0.1 1.9e-25 89.4 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_17 PF17668.1 EMT52993.1 - 3.2e-15 56.9 0.0 3.4e-14 53.6 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain SCP2_2 PF13530.6 EMT52993.1 - 1e-13 51.6 0.0 2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Sterol carrier protein domain Acetyltransf_10 PF13673.7 EMT52993.1 - 5.2e-06 26.4 0.0 0.00018 21.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT52993.1 - 9.7e-06 25.8 0.0 0.052 13.8 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EMT52993.1 - 0.0017 18.5 0.0 0.019 15.1 0.0 2.6 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain NUDIX PF00293.28 EMT52994.1 - 4.8e-11 42.8 0.1 7e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain PilP PF04351.13 EMT52994.1 - 0.039 13.9 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Pilus assembly protein, PilP GFO_IDH_MocA PF01408.22 EMT52995.1 - 2.4e-27 96.1 0.1 3.6e-27 95.6 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 EMT52995.1 - 2.1e-05 25.0 0.0 3.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 EMT52995.1 - 9.6e-05 22.8 0.0 0.00017 22.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Rossmann-like PF10727.9 EMT52995.1 - 0.00014 21.7 0.2 0.0018 18.1 0.3 2.4 2 1 0 2 2 2 1 Rossmann-like domain NAD_binding_3 PF03447.16 EMT52995.1 - 0.0028 18.3 0.1 0.0053 17.4 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EMT52995.1 - 0.0081 16.3 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.15 EMT52995.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EMT52995.1 - 0.083 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SDF PF00375.18 EMT52996.1 - 4.5e-122 407.8 42.1 5.1e-122 407.7 42.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SIS_2 PF13580.6 EMT52997.1 - 2.9e-13 50.0 0.0 5.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 SIS domain UBA_4 PF14555.6 EMT52997.1 - 4.2e-07 29.7 0.1 0.00046 19.9 0.0 2.4 1 1 1 2 2 2 2 UBA-like domain SIS PF01380.22 EMT52997.1 - 8.7e-06 25.6 1.4 5.8e-05 23.0 0.0 2.4 3 0 0 3 3 3 1 SIS domain ANTAR PF03861.14 EMT52997.1 - 0.029 14.2 1.0 8.6 6.3 0.1 2.5 2 0 0 2 2 2 0 ANTAR domain RCC1 PF00415.18 EMT52997.1 - 0.079 13.6 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Laminin_G_1 PF00054.23 EMT52997.1 - 0.11 12.7 0.3 0.24 11.6 0.3 1.5 1 0 0 1 1 1 0 Laminin G domain ABC_tran PF00005.27 EMT52998.1 - 4.5e-31 108.2 0.0 6.2e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT52998.1 - 3.4e-17 62.7 0.5 5.6e-17 62.0 0.5 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT52998.1 - 0.00019 21.4 0.1 0.013 15.3 0.2 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMT52998.1 - 0.00077 19.9 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EMT52998.1 - 0.0092 15.4 0.2 0.61 9.5 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT52998.1 - 0.039 14.2 0.8 0.17 12.2 0.8 2.0 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EMT52998.1 - 0.048 12.3 0.0 0.081 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Spp-24 PF07448.11 EMT52998.1 - 0.065 13.4 0.4 0.12 12.6 0.4 1.4 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain AAA_29 PF13555.6 EMT52998.1 - 0.078 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 EMT52998.1 - 0.18 11.5 0.1 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 EMT52999.1 - 4.6e-30 104.9 0.1 6.9e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT52999.1 - 4.5e-22 78.3 0.1 8.2e-22 77.5 0.1 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EMT52999.1 - 1.4e-08 34.5 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT52999.1 - 4.2e-05 23.5 0.2 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMT52999.1 - 0.0018 18.5 0.2 0.0067 16.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EMT52999.1 - 0.014 15.0 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EMT52999.1 - 0.016 15.6 0.0 0.036 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 EMT52999.1 - 0.016 14.9 0.5 0.026 14.2 0.5 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.18 EMT52999.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Lum_binding PF00677.17 EMT52999.1 - 0.093 12.7 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Lumazine binding domain TniB PF05621.11 EMT52999.1 - 0.1 12.0 0.7 0.51 9.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 EMT52999.1 - 0.16 12.4 1.4 4.2 7.8 1.4 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Beta-lactamase PF00144.24 EMT53000.1 - 7.4e-49 166.8 0.5 9.1e-49 166.5 0.5 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EMT53000.1 - 0.0017 18.0 0.1 0.0038 16.8 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase enzyme family Cupin_6 PF12852.7 EMT53000.1 - 0.075 12.8 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Cupin BPD_transp_1 PF00528.22 EMT53001.1 - 1.9e-31 109.3 8.9 1.9e-31 109.3 8.9 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT53001.1 - 2e-13 50.1 0.1 2e-13 50.1 0.1 3.3 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 EMT53002.1 - 1.1e-44 152.4 10.6 1.1e-44 152.4 10.6 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component bPH_5 PF10882.8 EMT53002.1 - 0.041 14.0 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain DUF5510 PF17629.2 EMT53002.1 - 0.17 11.8 4.0 3.7 7.5 0.0 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5510) SBP_bac_5 PF00496.22 EMT53003.1 - 1.3e-105 353.4 4.7 1.8e-105 353.0 4.7 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle AnmK PF03702.14 EMT53004.1 - 4.2e-107 358.4 0.0 5.3e-107 358.1 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Peptidase_M22 PF00814.25 EMT53004.1 - 0.0011 18.8 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Glycoprotease family BcrAD_BadFG PF01869.20 EMT53004.1 - 0.0045 16.5 0.0 0.0094 15.5 0.0 1.6 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family ATPgrasp_YheCD PF14398.6 EMT53005.1 - 8.3e-55 185.8 0.0 1.1e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EMT53005.1 - 2.6e-07 30.2 0.0 6.4e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 Sugar-transfer associated ATP-grasp TTL PF03133.15 EMT53005.1 - 0.00026 20.2 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family GSH-S_ATP PF02955.16 EMT53005.1 - 0.051 13.0 0.0 0.2 11.1 0.0 2.0 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain MscL PF01741.18 EMT53006.1 - 2.4e-43 147.3 2.5 3e-43 147.0 2.5 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DZR PF12773.7 EMT53006.1 - 0.016 15.2 1.1 0.024 14.6 1.1 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 EMT53006.1 - 0.084 12.9 0.4 0.11 12.5 0.4 1.2 1 0 0 1 1 1 0 zinc-ribbons UPF0547 PF10571.9 EMT53006.1 - 0.094 12.8 5.2 0.16 12.1 5.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 HypA PF01155.19 EMT53006.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Nodulin_late PF07127.11 EMT53006.1 - 0.14 12.5 1.3 0.25 11.7 1.3 1.4 1 0 0 1 1 1 0 Late nodulin protein IU_nuc_hydro PF01156.19 EMT53007.1 - 2.1e-97 326.4 0.6 2.4e-97 326.2 0.6 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase IU_nuc_hydro PF01156.19 EMT53008.1 - 2.2e-31 109.6 0.5 5.7e-29 101.6 0.5 2.9 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RPAP1_N PF08621.10 EMT53009.1 - 0.18 11.6 0.4 0.32 10.8 0.4 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal HrpB_C PF08482.10 EMT53010.1 - 1.3e-55 187.5 0.0 2.6e-55 186.4 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent helicase C-terminal Helicase_C PF00271.31 EMT53010.1 - 1.6e-14 54.1 0.0 4.7e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 EMT53010.1 - 1.6e-10 41.3 0.0 3.8e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 EMT53010.1 - 4.5e-06 26.5 0.0 8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 EMT53010.1 - 0.032 14.2 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain DUF2944 PF11161.8 EMT53010.1 - 0.12 12.2 0.1 0.32 10.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) UvrD-helicase PF00580.21 EMT53011.1 - 3.9e-14 52.9 5.0 1.6e-08 34.4 0.0 3.4 4 1 0 4 4 4 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EMT53011.1 - 2.6e-12 47.3 0.0 2.6e-11 44.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.6 EMT53011.1 - 6.7e-11 42.2 3.1 3.3e-05 23.5 0.0 2.8 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 EMT53011.1 - 4.3e-09 36.1 0.0 1.4e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 EMT53011.1 - 1.4e-05 24.7 0.0 0.18 11.2 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 EMT53011.1 - 3.6e-05 23.2 0.0 0.031 13.5 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EMT53011.1 - 5.1e-05 23.1 0.1 0.13 12.0 0.1 3.0 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EMT53011.1 - 9.5e-05 22.2 0.0 0.028 14.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EMT53011.1 - 0.0072 16.6 0.0 4.8 7.5 0.0 3.8 4 0 0 4 4 3 1 AAA domain DEAD PF00270.29 EMT53011.1 - 0.012 15.4 0.0 0.03 14.1 0.0 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase NACHT PF05729.12 EMT53011.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EMT53011.1 - 0.069 13.5 0.5 0.47 10.8 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain ResIII PF04851.15 EMT53011.1 - 0.092 12.7 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Carbpep_Y_N PF05388.11 EMT53011.1 - 0.12 13.0 0.2 0.35 11.4 0.2 1.7 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide AAA_13 PF13166.6 EMT53011.1 - 0.39 9.3 6.1 0.86 8.2 6.1 1.5 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.12 EMT53011.1 - 0.76 9.8 3.8 2.5 8.1 3.8 1.9 1 0 0 1 1 1 0 Laminin Domain II zinc_ribbon_13 PF09855.9 EMT53014.1 - 6.5e-23 80.7 0.1 6.5e-23 80.7 0.1 1.6 2 0 0 2 2 2 1 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Lar_restr_allev PF14354.6 EMT53014.1 - 0.0049 17.2 0.3 0.0049 17.2 0.3 2.1 1 1 1 2 2 2 1 Restriction alleviation protein Lar Anti-TRAP PF15777.5 EMT53014.1 - 2.1 8.4 9.2 0.4 10.7 3.5 2.3 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn-ribbon_8 PF09723.10 EMT53014.1 - 2.6 8.2 7.8 53 4.0 6.4 2.8 2 1 0 2 2 2 0 Zinc ribbon domain Mut7-C PF01927.16 EMT53014.1 - 3.7 7.7 6.1 2.8 8.0 3.5 1.7 1 1 0 1 1 1 0 Mut7-C RNAse domain DUF4501 PF14946.6 EMT53014.1 - 6 6.9 7.8 7.1 6.7 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) HypA PF01155.19 EMT53014.1 - 7.6 6.6 8.5 7.7 6.6 4.9 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA adh_short_C2 PF13561.6 EMT53015.1 - 6e-62 209.3 0.0 7.3e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT53015.1 - 8.1e-48 162.5 0.0 9.7e-48 162.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT53015.1 - 6.7e-06 26.1 0.0 9.1e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMT53015.1 - 0.093 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MCPsignal PF00015.21 EMT53016.1 - 2.8e-49 167.2 54.2 7.7e-48 162.5 24.8 4.1 1 1 2 4 4 4 3 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 EMT53016.1 - 5.5e-29 101.7 0.3 5.5e-29 101.7 0.3 4.9 3 2 2 5 5 5 1 Cache domain HAMP PF00672.25 EMT53016.1 - 2.9e-13 50.0 0.1 2.9e-13 50.0 0.1 5.0 6 0 0 6 6 5 1 HAMP domain Cache_3-Cache_2 PF17201.4 EMT53016.1 - 1e-08 34.8 0.3 1e-08 34.8 0.3 4.3 3 1 1 4 4 4 1 Cache 3/Cache 2 fusion domain DUF948 PF06103.11 EMT53016.1 - 1.1e-06 28.8 34.1 0.00063 19.9 1.5 5.9 2 2 2 4 4 4 2 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 EMT53016.1 - 1.7e-06 28.3 20.8 0.0044 17.3 1.4 5.2 2 2 2 4 4 4 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EMT53016.1 - 0.0027 17.7 25.8 0.037 14.0 2.6 4.7 3 2 2 5 5 4 3 Protein of unknown function (DUF1664) dCache_2 PF08269.11 EMT53016.1 - 0.0062 15.8 0.0 0.0062 15.8 0.0 3.3 3 1 0 3 3 3 1 Cache domain Lipoprotein_7 PF01540.16 EMT53016.1 - 0.015 14.6 0.8 0.015 14.6 0.8 2.4 1 1 1 2 2 2 0 Adhesin lipoprotein V_ATPase_I PF01496.19 EMT53016.1 - 0.064 11.2 16.7 0.075 10.9 13.9 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.12 EMT53016.1 - 0.07 13.1 28.4 0.076 13.0 3.0 4.2 2 2 3 5 5 5 0 Laminin Domain II sCache_2 PF17200.4 EMT53016.1 - 0.1 12.4 0.0 0.1 12.4 0.0 3.1 3 0 0 3 3 3 0 Single Cache domain 2 TRPM_tetra PF16519.5 EMT53016.1 - 0.25 11.5 4.4 1.7 8.8 0.2 3.6 2 1 1 3 3 3 0 Tetramerisation domain of TRPM Sec34 PF04136.15 EMT53016.1 - 0.39 10.6 14.8 2.2 8.1 0.4 4.4 2 2 2 4 4 4 0 Sec34-like family DASH_Duo1 PF08651.10 EMT53016.1 - 0.46 10.3 10.6 4.3 7.2 0.2 5.4 4 2 1 5 5 5 0 DASH complex subunit Duo1 Occludin_ELL PF07303.13 EMT53016.1 - 0.5 11.1 5.0 12 6.6 0.1 4.0 2 2 2 4 4 4 0 Occludin homology domain Mce4_CUP1 PF11887.8 EMT53016.1 - 0.5 9.8 18.1 2.4 7.5 3.5 3.5 1 1 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative AIP3 PF03915.13 EMT53016.1 - 0.52 9.3 21.2 0.2 10.7 3.5 2.3 1 1 1 2 2 2 0 Actin interacting protein 3 UPF0242 PF06785.11 EMT53016.1 - 1 9.4 14.5 0.22 11.6 3.2 3.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus IFT57 PF10498.9 EMT53016.1 - 1 8.2 18.1 1.5 7.7 5.9 3.0 2 2 1 3 3 3 0 Intra-flagellar transport protein 57 YkyA PF10368.9 EMT53016.1 - 1.4 8.6 19.2 2 8.0 6.3 3.2 2 2 0 2 2 2 0 Putative cell-wall binding lipoprotein DUF4200 PF13863.6 EMT53016.1 - 1.4 9.4 15.5 0.71 10.3 1.7 3.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) DUF1043 PF06295.12 EMT53016.1 - 1.4 8.9 14.8 3.2 7.8 1.3 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1043) ING PF12998.7 EMT53016.1 - 1.6 9.4 6.2 29 5.3 0.2 3.5 3 2 0 3 3 2 0 Inhibitor of growth proteins N-terminal histone-binding ZapB PF06005.12 EMT53016.1 - 1.7 9.2 15.1 3 8.4 0.3 4.5 4 1 0 4 4 4 0 Cell division protein ZapB CLZ PF16526.5 EMT53016.1 - 1.9 8.9 12.5 0.39 11.1 0.6 4.5 4 1 1 5 5 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Osmo_CC PF08946.10 EMT53016.1 - 2.7 8.3 8.3 15 5.9 0.0 4.8 5 0 0 5 5 4 0 Osmosensory transporter coiled coil Spc7 PF08317.11 EMT53016.1 - 2.7 6.8 25.1 0.43 9.4 8.5 2.5 1 1 0 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 EMT53016.1 - 4.5 6.4 16.8 1.1 8.5 2.4 2.8 2 1 1 3 3 3 0 TMPIT-like protein Collagen_mid PF15984.5 EMT53016.1 - 4.7 6.9 26.8 0.42 10.3 3.3 3.8 2 1 2 4 4 4 0 Bacterial collagen, middle region Fib_alpha PF08702.10 EMT53016.1 - 5.2 7.2 19.1 3.1 8.0 1.7 4.1 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.9 EMT53016.1 - 6.8 7.4 21.8 0.79 10.5 0.8 4.4 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.11 EMT53016.1 - 8.9 6.4 19.8 0.68 10.0 0.3 4.6 2 2 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 NUDIX PF00293.28 EMT53017.1 - 4.9e-20 71.9 0.2 5.8e-20 71.7 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain Lar_restr_allev PF14354.6 EMT53018.1 - 0.00067 20.0 0.3 0.00069 19.9 0.3 1.1 1 0 0 1 1 1 1 Restriction alleviation protein Lar zinc_ribbon_13 PF09855.9 EMT53018.1 - 0.00068 19.7 0.2 0.00089 19.4 0.2 1.2 1 0 0 1 1 1 1 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zinc_ribbon_2 PF13240.6 EMT53018.1 - 0.0043 16.7 0.3 2.5 7.9 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EMT53018.1 - 0.013 15.0 0.7 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding DUF1610 PF07754.11 EMT53018.1 - 0.42 10.6 5.9 5.8 7.0 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) SH3_3 PF08239.11 EMT53019.1 - 5.1e-06 26.7 1.0 0.0019 18.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial SH3 domain RtcB PF01139.17 EMT53020.1 - 4e-74 250.3 0.9 9.5e-74 249.0 0.9 1.5 1 1 0 1 1 1 1 tRNA-splicing ligase RtcB Oxidored_FMN PF00724.20 EMT53021.1 - 4.4e-79 266.2 0.0 5e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DHO_dh PF01180.21 EMT53021.1 - 0.00019 20.7 0.0 0.00066 19.0 0.0 1.8 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EMT53021.1 - 0.0061 15.6 1.1 0.078 12.0 0.0 2.5 3 0 0 3 3 3 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EMT53021.1 - 0.058 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Dus PF01207.17 EMT53021.1 - 0.082 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) His_Phos_1 PF00300.22 EMT53022.1 - 2.8e-10 40.2 0.0 6.7e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Epimerase PF01370.21 EMT53023.1 - 5.4e-14 52.2 0.0 5e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DUF1731 PF08338.11 EMT53023.1 - 2.1e-12 46.7 0.0 4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) GDP_Man_Dehyd PF16363.5 EMT53023.1 - 2e-08 34.0 0.1 0.02 14.3 0.0 3.0 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase KR PF08659.10 EMT53023.1 - 0.015 15.3 0.0 0.033 14.1 0.0 1.6 2 0 0 2 2 2 0 KR domain RmlD_sub_bind PF04321.17 EMT53023.1 - 0.016 14.4 0.0 0.028 13.5 0.0 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain RXLR PF16810.5 EMT53024.1 - 0.078 13.4 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity DUF3072 PF11272.8 EMT53024.1 - 0.16 11.9 0.5 0.31 11.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Glyco_tranf_2_3 PF13641.6 EMT53027.1 - 4.1e-32 111.9 0.0 5.2e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EMT53027.1 - 3.3e-24 85.6 0.0 5e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EMT53027.1 - 4.9e-20 72.3 6.1 4.9e-20 72.3 6.1 2.1 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EMT53027.1 - 2.2e-13 50.0 0.1 3.3e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 EMT53027.1 - 2.7e-12 46.1 4.2 4.6e-08 32.1 0.0 3.1 1 1 2 3 3 3 2 Chitin synthase Glyco_tranf_2_2 PF10111.9 EMT53027.1 - 1.2e-06 28.2 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EMT53027.1 - 0.00055 20.4 0.0 0.0014 19.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Trans_reg_C PF00486.28 EMT53028.1 - 2.3e-15 56.4 0.0 3.4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FHA PF00498.26 EMT53028.1 - 7.9e-14 51.8 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EMT53028.1 - 2.4e-05 24.5 0.0 4.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain HSP90 PF00183.18 EMT53029.1 - 3.2e-113 379.4 26.0 1.3e-108 364.2 17.0 2.7 2 1 1 3 3 3 2 Hsp90 protein HATPase_c_3 PF13589.6 EMT53029.1 - 2.9e-12 46.6 0.4 6e-12 45.6 0.4 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EMT53029.1 - 1.2e-11 45.1 0.1 2.5e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SpuA_C PF18033.1 EMT53029.1 - 0.054 13.5 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 SpuA C-terminal GD_AH_C PF04295.13 EMT53029.1 - 0.1 11.3 0.1 0.19 10.5 0.1 1.3 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus PBP_like_2 PF12849.7 EMT53030.1 - 4.2e-22 79.1 0.0 6.7e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 EMT53030.1 - 0.00011 21.4 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 EMT53030.1 - 0.00093 19.0 0.0 0.0016 18.2 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF2157 PF09925.9 EMT53030.1 - 0.29 10.9 5.3 0.49 10.2 5.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Phage_holin_3_6 PF07332.11 EMT53030.1 - 2.4 8.2 6.0 4.9 7.2 6.0 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 EMT53030.1 - 4 7.0 5.4 0.89 9.2 1.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) HMGL-like PF00682.19 EMT53031.1 - 4.2e-87 292.1 1.2 5.9e-87 291.6 1.2 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EMT53031.1 - 5.1e-30 104.1 0.8 1.1e-29 103.0 0.1 1.9 2 0 0 2 2 2 1 LeuA allosteric (dimerisation) domain Hus1 PF04005.12 EMT53031.1 - 0.059 12.5 0.0 3.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Hus1-like protein Glyoxalase PF00903.25 EMT53032.1 - 7.3e-07 29.4 0.0 1.6e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EMT53032.1 - 0.0016 19.2 0.0 0.0021 18.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EMT53032.1 - 0.0019 18.1 0.0 0.012 15.6 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain DoxX_2 PF13564.6 EMT53033.1 - 1.5e-19 70.0 8.6 1.8e-19 69.8 8.6 1.1 1 0 0 1 1 1 1 DoxX-like family Glyoxalase PF00903.25 EMT53034.1 - 1.1e-12 48.2 0.1 1.5e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EMT53034.1 - 0.00038 20.4 0.0 0.0007 19.5 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EMT53034.1 - 0.0023 18.7 0.0 0.005 17.6 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain HTH_18 PF12833.7 EMT53035.1 - 2.2e-15 56.7 0.0 3.5e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EMT53035.1 - 5.5e-11 42.3 0.1 6.4e-08 32.5 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family TniQ PF06527.11 EMT53035.1 - 0.042 14.6 0.2 0.16 12.7 0.2 2.0 1 1 0 1 1 1 0 TniQ DUF3791 PF12668.7 EMT53035.1 - 0.052 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) HTH_DeoR PF08220.12 EMT53035.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Arabinose_bd PF12625.7 EMT53036.1 - 1.3e-33 116.7 0.0 2e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 EMT53036.1 - 4.9e-14 52.4 0.5 1.5e-13 50.8 0.5 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EMT53036.1 - 1.5e-08 34.5 0.8 9.2e-08 32.0 0.1 2.6 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix proteins, AraC family SurA_N PF09312.11 EMT53036.1 - 0.00089 19.3 0.1 0.0042 17.1 0.0 2.2 3 0 0 3 3 3 1 SurA N-terminal domain V-ATPase_C PF03223.15 EMT53036.1 - 0.044 13.2 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit C Flavodoxin_2 PF02525.17 EMT53037.1 - 3.6e-46 157.4 0.0 4.2e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EMT53037.1 - 6.3e-17 61.7 0.0 8.9e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DinB_2 PF12867.7 EMT53039.1 - 5.7e-17 62.4 4.4 6.6e-17 62.2 4.4 1.0 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 EMT53039.1 - 3.8e-06 27.4 1.1 2.1e-05 25.0 0.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF664) DinB PF05163.12 EMT53039.1 - 1.1e-05 25.4 1.7 1.5e-05 25.0 1.7 1.2 1 0 0 1 1 1 1 DinB family MDMPI_N PF11716.8 EMT53039.1 - 0.01 16.5 0.4 0.014 16.1 0.4 1.4 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF1572 PF07609.11 EMT53039.1 - 0.025 14.4 0.1 0.15 11.9 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1572) Sld5 PF05916.11 EMT53039.1 - 0.033 14.7 0.1 0.056 13.9 0.1 1.5 1 1 0 1 1 1 0 GINS complex protein Penicil_amidase PF01804.18 EMT53040.1 - 8.2e-232 771.9 4.8 9.7e-232 771.7 4.8 1.0 1 0 0 1 1 1 1 Penicillin amidase DUF3413 PF11893.8 EMT53040.1 - 0.12 11.5 0.2 0.36 9.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) Sigma_reg_N PF13800.6 EMT53040.1 - 0.19 12.0 0.2 0.51 10.7 0.2 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Type2_restr_D3 PF16902.5 EMT53040.1 - 0.2 11.6 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain DUF3040 PF11239.8 EMT53040.1 - 0.22 11.8 0.4 73 3.7 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Sigma70_r2 PF04542.14 EMT53041.1 - 9.2e-15 54.2 0.0 1.8e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT53041.1 - 4.3e-09 35.9 0.8 7.6e-09 35.1 0.8 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT53041.1 - 0.00047 19.6 0.4 0.00087 18.8 0.4 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT53041.1 - 0.0018 18.2 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 2 ECF sigma factor HTH_38 PF13936.6 EMT53041.1 - 0.053 13.3 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4367 PF14285.6 EMT53042.1 - 0.00027 21.3 2.6 0.00027 21.3 2.6 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4367) Cas_Cas6 PF01881.16 EMT53042.1 - 0.053 14.1 1.7 0.13 12.8 1.6 1.7 1 1 0 1 1 1 0 CRISPR associated protein Cas6 DUF4488 PF14869.6 EMT53042.1 - 0.63 10.0 4.3 0.7 9.8 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4488) DUF1450 PF07293.11 EMT53043.1 - 0.013 15.3 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) Acetyltransf_1 PF00583.25 EMT53044.1 - 8.8e-14 51.8 0.0 3.1e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT53044.1 - 1.6e-12 47.4 0.0 9.5e-12 45.0 0.0 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT53044.1 - 6.2e-11 42.6 0.0 3.2e-10 40.3 0.0 2.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EMT53044.1 - 0.00022 21.4 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMT53044.1 - 0.0004 21.1 0.0 0.0009 19.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT53044.1 - 0.00074 19.7 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT53044.1 - 0.012 15.5 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 EMT53044.1 - 0.068 13.3 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF1947 PF09183.10 EMT53044.1 - 0.086 13.2 0.2 0.46 10.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) Amidohydro_2 PF04909.14 EMT53045.1 - 2.7e-27 96.3 2.3 4e-27 95.8 2.3 1.3 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 EMT53045.1 - 9.9e-10 38.2 0.0 2.8e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 TatD related DNase Isochorismatase PF00857.20 EMT53047.1 - 4e-44 150.9 0.0 4.6e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family WG_beta_rep PF14903.6 EMT53048.1 - 7.3e-32 109.3 6.5 1.8e-09 37.7 0.0 6.0 4 2 2 6 6 6 4 WG containing repeat Sel1 PF08238.12 EMT53048.1 - 8.7e-22 77.1 26.9 5.8e-08 33.2 0.7 7.0 7 0 0 7 7 7 4 Sel1 repeat TPR_7 PF13176.6 EMT53048.1 - 0.014 15.3 13.0 9.3 6.5 0.1 6.7 6 1 1 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EMT53048.1 - 0.19 12.0 6.0 1.4 9.2 0.5 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EMT53048.1 - 0.26 12.0 13.0 3.1 8.5 0.3 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMT53048.1 - 3 8.3 7.7 17 5.9 0.5 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EMT53048.1 - 3.4 8.2 10.9 3.6 8.2 0.2 5.7 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMT53048.1 - 5 8.0 8.1 1.1e+02 3.7 0.0 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 EMT53049.1 - 2.2e-52 178.2 70.5 6.1e-43 147.1 42.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT53049.1 - 1.7e-11 43.7 36.2 2.4e-10 39.9 16.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EMT53049.1 - 6.8e-07 28.5 27.8 0.00012 21.1 11.8 2.5 1 1 1 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 EMT53049.1 - 0.00057 18.6 14.1 0.00057 18.6 14.1 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein MarR_2 PF12802.7 EMT53050.1 - 4.1e-12 45.8 1.4 2.1e-11 43.6 0.2 2.3 2 0 0 2 2 2 1 MarR family MarR PF01047.22 EMT53050.1 - 3.6e-11 42.8 0.4 5.9e-11 42.1 0.4 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EMT53050.1 - 1.7e-05 25.2 0.1 4.3e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_34 PF13601.6 EMT53050.1 - 4.5e-05 23.5 0.0 7.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 EMT53050.1 - 0.0003 20.7 0.4 0.00061 19.7 0.4 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 EMT53050.1 - 0.00043 20.4 0.0 0.00087 19.4 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 EMT53050.1 - 0.00089 19.1 0.0 0.0019 18.0 0.0 1.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 EMT53050.1 - 0.00092 19.0 0.1 0.0019 18.0 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 EMT53050.1 - 0.0013 18.2 0.1 0.0034 16.9 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 EMT53050.1 - 0.015 15.7 0.1 0.044 14.1 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator Ribosomal_S25 PF03297.15 EMT53050.1 - 0.029 14.6 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 S25 ribosomal protein HTH_36 PF13730.6 EMT53050.1 - 0.18 11.8 0.4 0.46 10.5 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3116 PF11313.8 EMT53050.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) Epimerase PF01370.21 EMT53051.1 - 2.7e-11 43.4 0.1 8.7e-11 41.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMT53051.1 - 4.3e-11 43.0 0.0 5.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EMT53051.1 - 6.1e-06 25.8 0.0 8.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EMT53051.1 - 4.8e-05 23.0 0.0 0.00018 21.2 0.0 1.9 3 0 0 3 3 3 1 NmrA-like family RmlD_sub_bind PF04321.17 EMT53051.1 - 5.2e-05 22.5 0.0 0.00011 21.4 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EMT53051.1 - 8.2e-05 22.1 0.1 0.0077 15.7 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMT53051.1 - 0.002 17.2 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EMT53051.1 - 0.19 11.6 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 KR domain TetR_N PF00440.23 EMT53052.1 - 8.9e-15 54.2 1.9 1.9e-14 53.2 1.9 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 EMT53052.1 - 0.017 15.3 0.3 0.041 14.1 0.1 1.8 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CitG PF01874.16 EMT53052.1 - 0.045 13.4 0.1 0.049 13.3 0.1 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase FGE-sulfatase PF03781.16 EMT53053.1 - 7.1e-40 137.2 5.8 1.9e-38 132.6 5.8 2.3 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DUF4180 PF13788.6 EMT53054.1 - 7.7e-45 151.4 0.1 8.7e-45 151.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4180) TetR_N PF00440.23 EMT53055.1 - 6.2e-11 41.9 0.1 3.1e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 EMT53055.1 - 1.8e-07 31.4 0.0 3.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal HTH_3 PF01381.22 EMT53055.1 - 6.8e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix DUF2073 PF09846.9 EMT53055.1 - 0.017 15.0 0.1 0.27 11.1 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) TetR_C_7 PF14246.6 EMT53055.1 - 0.04 14.0 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain SL4P PF17618.2 EMT53055.1 - 0.051 13.6 0.6 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein HTH_31 PF13560.6 EMT53055.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TetR_C_24 PF17932.1 EMT53055.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_19 PF13245.6 EMT53056.1 - 9e-11 42.3 0.0 8e-10 39.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.6 EMT53056.1 - 8.1e-10 38.6 0.4 1.4e-05 24.6 0.0 4.5 2 2 1 4 4 4 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EMT53056.1 - 8.5e-09 35.4 1.8 8.5e-09 35.4 1.8 3.7 1 1 2 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 EMT53056.1 - 9.8e-09 34.9 0.0 2.3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EMT53056.1 - 1.6e-07 31.3 0.2 0.002 17.9 0.1 3.1 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EMT53056.1 - 0.00033 20.2 0.1 0.31 10.4 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_12 PF13087.6 EMT53056.1 - 0.0032 17.1 3.3 0.16 11.6 0.0 3.2 2 1 0 3 3 3 1 AAA domain DUF2075 PF09848.9 EMT53056.1 - 0.005 16.1 1.3 0.12 11.6 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) DUF2205 PF10224.9 EMT53056.1 - 0.025 14.6 3.2 0.2 11.6 1.7 2.9 2 0 0 2 2 2 0 Short coiled-coil protein DEAD PF00270.29 EMT53056.1 - 0.026 14.3 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 EMT53056.1 - 0.065 13.2 1.1 0.19 11.7 0.1 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MnmE_helical PF12631.7 EMT53056.1 - 0.2 11.8 10.5 0.2 11.8 4.0 3.1 2 1 0 2 2 2 0 MnmE helical domain zf-C2H2_aberr PF17017.5 EMT53056.1 - 4.5 7.4 7.5 0.36 11.0 0.4 2.6 3 0 0 3 3 3 0 Aberrant zinc-finger Atg14 PF10186.9 EMT53056.1 - 9.9 5.1 9.2 0.42 9.7 1.1 2.4 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 TetR_N PF00440.23 EMT53057.1 - 2.1e-18 65.8 0.3 4.3e-18 64.8 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family FANCF PF11107.8 EMT53057.1 - 0.0031 16.8 0.1 0.004 16.4 0.1 1.2 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) HTH_Tnp_1_2 PF13022.6 EMT53057.1 - 0.023 14.8 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Sigma70_r4_2 PF08281.12 EMT53057.1 - 0.028 14.1 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 LacI PF00356.21 EMT53057.1 - 0.18 11.6 0.7 6.6 6.6 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Abhydrolase_1 PF00561.20 EMT53058.1 - 1.5e-19 70.7 0.0 7.7e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMT53058.1 - 3.7e-18 67.0 0.4 4.4e-18 66.7 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMT53058.1 - 6.4e-13 48.5 0.0 1.8e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EMT53058.1 - 9e-06 24.6 0.0 1.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 EMT53058.1 - 0.00045 20.1 0.0 0.00063 19.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 EMT53058.1 - 0.0014 18.6 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 EMT53058.1 - 0.014 15.2 0.0 0.028 14.1 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein DUF915 PF06028.11 EMT53058.1 - 0.019 14.3 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 EMT53058.1 - 0.027 14.4 0.1 0.084 12.7 0.0 1.9 2 1 0 2 2 2 0 Lipase (class 3) Esterase PF00756.20 EMT53058.1 - 0.068 12.8 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 EMT53058.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 EMT53058.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 EMT53058.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EMT53058.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase LysE PF01810.18 EMT53059.1 - 2.8e-17 62.8 11.2 3.2e-17 62.6 11.2 1.1 1 0 0 1 1 1 1 LysE type translocator DUF2417 PF10329.9 EMT53059.1 - 0.00016 21.2 4.5 0.00021 20.8 4.5 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF2678 PF10856.8 EMT53059.1 - 0.031 14.2 3.1 0.071 13.0 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) TerC PF03741.16 EMT53059.1 - 0.072 12.8 9.6 0.29 10.8 9.0 2.2 1 1 0 1 1 1 0 Integral membrane protein TerC family LysR_substrate PF03466.20 EMT53060.1 - 1.4e-31 109.5 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT53060.1 - 1.7e-14 53.5 0.0 2.9e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 EMT53060.1 - 0.047 13.3 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ABC_tran PF00005.27 EMT53061.1 - 4e-23 82.5 0.0 2.7e-13 50.6 0.0 3.6 3 1 0 3 3 3 3 ABC transporter SMC_N PF02463.19 EMT53061.1 - 4.9e-09 36.0 1.8 0.26 10.7 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT53061.1 - 8.1e-09 35.7 2.0 0.053 13.3 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT53061.1 - 9e-09 35.0 0.2 0.007 16.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT53061.1 - 1.6e-08 35.1 0.0 0.0013 19.1 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EMT53061.1 - 3.7e-07 30.2 0.3 0.0087 16.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase UvrA_DNA-bind PF17755.1 EMT53061.1 - 4e-07 30.4 0.1 1.9e-06 28.2 0.3 2.1 2 0 0 2 2 1 1 UvrA DNA-binding domain Viral_helicase1 PF01443.18 EMT53061.1 - 9.7e-07 28.8 0.0 0.0003 20.6 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EMT53061.1 - 3.4e-05 24.2 0.2 0.011 15.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMT53061.1 - 8.5e-05 22.7 0.0 0.066 13.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EMT53061.1 - 0.00013 22.6 2.0 0.24 11.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 EMT53061.1 - 0.00033 20.3 0.6 0.039 13.5 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 EMT53061.1 - 0.0004 20.2 4.1 6.9 6.3 0.0 4.5 4 1 0 4 4 4 0 AAA ATPase domain DnaJ_CXXCXGXG PF00684.19 EMT53061.1 - 0.00041 20.7 5.2 0.21 11.9 0.2 3.5 3 0 0 3 3 3 1 DnaJ central domain AAA_7 PF12775.7 EMT53061.1 - 0.00099 18.7 0.4 1.5 8.3 0.0 2.6 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_30 PF13604.6 EMT53061.1 - 0.0013 18.5 0.4 0.19 11.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EMT53061.1 - 0.0014 18.3 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 EMT53061.1 - 0.0026 17.1 0.2 0.22 10.7 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 EMT53061.1 - 0.0028 17.7 0.0 2.3 8.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMT53061.1 - 0.0038 17.8 0.1 1.1 9.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain ATPase PF06745.13 EMT53061.1 - 0.0089 15.4 0.4 2.7 7.3 0.0 2.9 3 0 0 3 3 3 1 KaiC T2SSE PF00437.20 EMT53061.1 - 0.0094 15.0 0.4 2.8 6.9 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_24 PF13479.6 EMT53061.1 - 0.02 14.6 0.1 0.33 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EMT53061.1 - 0.029 14.2 0.2 9.1 6.1 0.0 2.9 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 EMT53061.1 - 0.041 13.1 0.0 0.69 9.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain RNA12 PF10443.9 EMT53061.1 - 0.041 12.6 0.0 0.64 8.7 0.0 2.2 2 0 0 2 2 2 0 RNA12 protein ATP_bind_1 PF03029.17 EMT53061.1 - 0.069 12.9 0.3 0.78 9.5 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 EMT53061.1 - 0.072 13.0 0.1 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 EMT53061.1 - 0.092 12.0 0.0 3.9 6.7 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin MeaB PF03308.16 EMT53061.1 - 0.11 11.5 0.6 2.1 7.2 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3365 PF11845.8 EMT53061.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3365) HTH_5 PF01022.20 EMT53062.1 - 2e-15 56.4 0.0 2.8e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EMT53062.1 - 8.9e-12 44.9 0.0 1.4e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EMT53062.1 - 9e-08 31.9 0.1 1.2e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 EMT53062.1 - 5.1e-07 29.5 0.1 7.6e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 EMT53062.1 - 9e-05 22.3 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 EMT53062.1 - 9.8e-05 22.4 0.1 0.00014 21.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 EMT53062.1 - 0.00017 21.3 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 EMT53062.1 - 0.00038 20.0 0.1 0.00062 19.3 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 EMT53062.1 - 0.00078 19.9 0.0 0.001 19.5 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain Arg_repressor PF01316.21 EMT53062.1 - 0.0012 18.6 0.1 0.0021 17.8 0.1 1.5 1 1 0 1 1 1 1 Arginine repressor, DNA binding domain HTH_23 PF13384.6 EMT53062.1 - 0.003 17.3 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain RP-C PF03428.13 EMT53062.1 - 0.008 15.9 0.1 0.011 15.4 0.1 1.1 1 0 0 1 1 1 1 Replication protein C N-terminal domain HTH_11 PF08279.12 EMT53062.1 - 0.0094 15.9 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 HTH domain Fe_dep_repress PF01325.19 EMT53062.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 EMT53062.1 - 0.015 15.6 0.1 0.024 15.0 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_9 PF08221.11 EMT53062.1 - 0.019 15.0 0.1 0.03 14.4 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_45 PF14947.6 EMT53062.1 - 0.019 14.9 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix LexA_DNA_bind PF01726.16 EMT53062.1 - 0.021 14.6 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 LexA DNA binding domain HTH_Crp_2 PF13545.6 EMT53062.1 - 0.04 13.9 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_29 PF13551.6 EMT53062.1 - 0.045 13.8 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn helix HTH_34 PF13601.6 EMT53062.1 - 0.059 13.6 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_DeoR PF08220.12 EMT53062.1 - 0.062 13.1 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HxlR PF01638.17 EMT53062.1 - 0.063 13.1 0.1 0.1 12.5 0.1 1.3 1 1 0 1 1 1 0 HxlR-like helix-turn-helix GntR PF00392.21 EMT53062.1 - 0.066 12.9 0.3 0.1 12.2 0.3 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_12 PF08461.10 EMT53062.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain CENP-B_N PF04218.13 EMT53062.1 - 0.11 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF1062 PF06353.12 EMT53063.1 - 4e-42 144.2 0.0 4e-42 144.2 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1062) NRDD PF13597.6 EMT53063.1 - 0.0021 16.9 1.2 0.0031 16.4 1.2 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase DZR PF12773.7 EMT53063.1 - 0.032 14.3 0.4 0.069 13.2 0.4 1.5 1 1 0 1 1 1 0 Double zinc ribbon DUF4379 PF14311.6 EMT53063.1 - 0.055 13.8 0.7 0.055 13.8 0.7 2.3 1 1 1 2 2 2 0 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 EMT53063.1 - 0.06 13.5 0.7 11 6.2 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 EMT53063.1 - 2.5 8.1 6.2 14 5.7 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Mor PF08765.11 EMT53064.1 - 3.7e-08 33.3 0.8 4.1e-07 30.0 0.8 2.0 1 1 0 1 1 1 1 Mor transcription activator family GerE PF00196.19 EMT53064.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family WYL PF13280.6 EMT53065.1 - 6.7e-26 91.4 0.3 8.9e-26 91.0 0.3 1.2 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 EMT53065.1 - 6.3e-10 38.9 0.0 1.6e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_Tnp_4 PF13613.6 EMT53065.1 - 0.00023 20.8 0.0 0.00052 19.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Rrf2 PF02082.20 EMT53065.1 - 0.00095 19.5 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_DeoR PF08220.12 EMT53065.1 - 0.0025 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_10 PF04967.12 EMT53065.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain ADH_zinc_N PF00107.26 EMT53066.1 - 1.7e-15 57.2 1.0 2.9e-15 56.4 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMT53066.1 - 1.3e-10 42.4 0.0 2.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMT53066.1 - 1.3e-09 37.9 0.0 4.4e-09 36.2 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 EMT53066.1 - 0.027 14.4 0.4 0.041 13.8 0.4 1.3 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 EMT53066.1 - 0.097 12.1 0.3 0.17 11.3 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 EMT53066.1 - 0.16 11.5 0.2 0.23 11.0 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family DoxX_2 PF13564.6 EMT53067.1 - 1e-06 28.8 2.1 1.5e-06 28.2 2.1 1.5 1 0 0 1 1 1 1 DoxX-like family DoxX PF07681.12 EMT53067.1 - 5.3 7.7 9.5 0.57 10.8 3.6 2.3 2 1 0 2 2 2 0 DoxX SGL PF08450.12 EMT53068.1 - 4.1e-11 42.9 0.9 0.023 14.3 0.0 5.7 1 1 3 5 5 5 4 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 EMT53068.1 - 2.3e-05 24.5 1.5 0.19 11.6 0.0 4.9 1 1 1 3 3 3 1 Esterase-like activity of phytase Reg_prop PF07494.11 EMT53068.1 - 4.7e-05 23.1 0.0 52 4.6 0.0 6.1 6 0 0 6 6 6 0 Two component regulator propeller Sox17_18_mid PF12067.8 EMT53068.1 - 0.0011 18.9 0.0 3.6 7.7 0.0 3.8 4 0 0 4 4 4 1 Sox 17/18 central domain NHL PF01436.21 EMT53068.1 - 0.004 17.1 0.0 0.14 12.3 0.0 3.1 2 0 0 2 2 2 1 NHL repeat DUF5074 PF16819.5 EMT53068.1 - 0.12 12.4 0.1 13 5.9 0.0 3.7 4 2 0 4 4 4 0 Domain of unknown function (DUF5074) MerR PF00376.23 EMT53071.1 - 8.9e-24 83.0 0.1 1.5e-12 47.0 0.1 2.6 2 0 0 2 2 2 2 MerR family regulatory protein MerR_1 PF13411.6 EMT53071.1 - 4.7e-21 74.7 0.0 1.3e-10 41.2 0.0 2.8 2 1 1 3 3 3 2 MerR HTH family regulatory protein DUF1836 PF08876.11 EMT53071.1 - 4.5e-06 26.7 0.1 0.05 13.7 0.0 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF1836) HTH_17 PF12728.7 EMT53071.1 - 0.016 15.4 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain KASH_CCD PF14662.6 EMT53071.1 - 0.023 14.5 2.9 0.026 14.3 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH HTH_3 PF01381.22 EMT53071.1 - 0.035 14.1 0.0 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix HTH_49 PF18010.1 EMT53071.1 - 0.1 12.5 0.1 6.1 6.8 0.0 3.1 3 0 0 3 3 3 0 Cry35Ab1 HTH C-terminal domain Cir_N PF10197.9 EMT53071.1 - 4.4 7.6 7.6 9.1 6.6 7.6 1.5 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Peptidase_M75 PF09375.10 EMT53072.1 - 2.5e-40 138.8 1.0 2.5e-40 138.8 1.0 1.4 1 1 0 1 1 1 1 Imelysin GHL13 PF14883.6 EMT53072.1 - 0.0063 15.6 1.1 0.016 14.3 0.3 1.9 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase family 13 PIF1 PF05970.14 EMT53072.1 - 0.029 13.5 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase LPAM_2 PF13627.6 EMT53072.1 - 0.24 11.3 4.4 0.4 10.6 4.4 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site GCN5L1 PF06320.13 EMT53072.1 - 2 8.6 5.6 10 6.3 0.6 3.6 4 1 1 5 5 5 0 GCN5-like protein 1 (GCN5L1) Dyp_perox PF04261.12 EMT53073.1 - 5.7e-105 350.9 0.0 6.5e-105 350.7 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family TAT_signal PF10518.9 EMT53073.1 - 0.0016 18.2 2.2 0.0035 17.1 2.2 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence FTR1 PF03239.14 EMT53074.1 - 3.3e-26 92.2 15.0 7.2e-26 91.1 15.0 1.5 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4363 PF14276.6 EMT53074.1 - 6.5e-05 23.0 10.2 0.14 12.3 1.2 3.9 4 0 0 4 4 4 3 Domain of unknown function (DUF4363) PDR_assoc PF08370.11 EMT53074.1 - 0.028 14.1 0.2 0.086 12.6 0.2 1.9 1 0 0 1 1 1 0 Plant PDR ABC transporter associated LPD22 PF18834.1 EMT53074.1 - 0.031 14.5 1.1 0.1 12.8 1.1 1.9 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 SesA PF17107.5 EMT53074.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.6 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3347 PF11827.8 EMT53074.1 - 0.56 10.4 2.3 0.94 9.6 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) ATG16 PF08614.11 EMT53074.1 - 0.84 9.8 3.5 1 9.5 1.9 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FKBP_N PF01346.18 EMT53074.1 - 1.3 10.0 4.0 17 6.5 0.0 2.8 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4293 PF14126.6 EMT53074.1 - 8.1 6.7 8.5 9.3 6.5 6.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Cu_amine_oxidN1 PF07833.11 EMT53075.1 - 2.6e-36 124.0 2.2 6.1e-36 122.8 0.3 2.7 3 0 0 3 3 3 1 Copper amine oxidase N-terminal domain FlgD_ig PF13860.6 EMT53075.1 - 2e-08 34.0 2.8 0.032 14.1 0.1 5.7 4 2 0 4 4 4 3 FlgD Ig-like domain Y_Y_Y PF07495.13 EMT53075.1 - 0.00086 19.2 0.2 28 4.8 0.0 4.6 4 0 0 4 4 4 0 Y_Y_Y domain fn3 PF00041.21 EMT53075.1 - 0.0035 17.6 1.3 0.017 15.5 0.4 2.6 2 0 0 2 2 2 1 Fibronectin type III domain TcfC PF16967.5 EMT53075.1 - 0.013 15.0 0.3 5.1 6.7 0.0 3.8 4 0 0 4 4 4 0 E-set like domain DUF4399 PF14347.6 EMT53075.1 - 0.016 15.6 0.0 11 6.5 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4399) DUF2271 PF10029.9 EMT53075.1 - 0.021 14.5 0.0 14 5.3 0.0 4.4 4 1 1 5 5 5 0 Predicted periplasmic protein (DUF2271) DUF2586 PF10758.9 EMT53075.1 - 0.027 13.7 0.3 3 6.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2586) DUF5625 PF18539.1 EMT53075.1 - 0.036 14.4 1.7 4.4 7.6 0.1 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF5625) Cadherin_pro PF08758.11 EMT53075.1 - 0.093 12.9 0.0 47 4.3 0.0 3.4 3 0 0 3 3 3 0 Cadherin prodomain like Arm-DNA-bind_5 PF17293.2 EMT53075.1 - 0.32 11.4 1.1 29 5.2 0.0 4.0 5 0 0 5 5 5 0 Arm DNA-binding domain Big_2 PF02368.18 EMT53076.1 - 4.4e-43 145.1 101.1 7.7e-08 32.1 4.2 10.4 10 0 0 10 10 10 10 Bacterial Ig-like domain (group 2) Big_3 PF07523.12 EMT53076.1 - 0.0017 18.6 79.4 0.63 10.4 0.2 13.3 10 7 0 10 10 10 8 Bacterial Ig-like domain (group 3) DUF190 PF02641.15 EMT53076.1 - 0.034 14.5 0.9 1.7 9.1 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized ACR, COG1993 N36 PF11438.8 EMT53076.1 - 0.18 11.6 0.9 6.3 6.7 0.0 3.1 3 0 0 3 3 3 0 36-mer N-terminal peptide of the N protein (N36) DUF218 PF02698.17 EMT53077.1 - 4e-33 114.2 0.0 6.7e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain CoA_trans PF01144.23 EMT53077.1 - 0.0098 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Coenzyme A transferase AAA_19 PF13245.6 EMT53077.1 - 0.03 14.7 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaI_N PF07319.11 EMT53078.1 - 5.3e-14 52.7 0.2 3.3e-13 50.1 0.0 2.4 3 0 0 3 3 3 1 Primosomal protein DnaI N-terminus IstB_IS21 PF01695.17 EMT53078.1 - 3.8e-13 49.6 0.0 4.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 EMT53078.1 - 2.4e-10 40.6 0.0 3.6e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein AFG1_ATPase PF03969.16 EMT53078.1 - 1.7e-08 33.8 0.0 2.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 AFG1-like ATPase AAA PF00004.29 EMT53078.1 - 1.9e-05 25.1 0.0 3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT53078.1 - 0.0011 19.4 0.1 0.0031 17.9 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EMT53078.1 - 0.0035 17.7 0.0 0.0089 16.4 0.0 1.7 1 1 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 EMT53078.1 - 0.012 15.9 0.1 0.12 12.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 EMT53078.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EMT53078.1 - 0.049 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EMT53078.1 - 0.071 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EMT53078.1 - 0.094 12.6 0.1 0.83 9.6 0.0 2.4 2 1 1 3 3 3 0 NTPase DnaB_2 PF07261.11 EMT53079.1 - 7.8e-09 35.2 0.0 1.8e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Replication initiation and membrane attachment DUF2120 PF09893.9 EMT53079.1 - 0.12 12.5 0.1 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) CCDC53 PF10152.9 EMT53079.1 - 0.22 11.9 3.0 0.5 10.8 3.0 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Ribosomal_S17e PF00833.18 EMT53079.1 - 7.6 6.5 7.6 0.81 9.6 1.8 2.3 3 0 0 3 3 3 0 Ribosomal S17 ATP-cone PF03477.16 EMT53080.1 - 1.3e-18 67.3 0.3 1.7e-18 67.0 0.3 1.1 1 0 0 1 1 1 1 ATP cone domain MAP65_ASE1 PF03999.12 EMT53080.1 - 0.022 13.5 0.1 0.022 13.5 0.1 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TACC_C PF05010.14 EMT53080.1 - 0.031 14.1 0.2 0.035 13.9 0.2 1.0 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TF_AP-2 PF03299.14 EMT53080.1 - 0.047 13.6 0.1 0.078 12.9 0.1 1.4 1 1 1 2 2 2 0 Transcription factor AP-2 POTRA_2 PF08479.11 EMT53080.1 - 0.068 13.0 0.0 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 POTRA domain, ShlB-type HD PF01966.22 EMT53081.1 - 2.2e-12 47.2 0.3 3.9e-12 46.5 0.3 1.4 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 EMT53081.1 - 4.7e-12 46.0 0.1 9.5e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 EMT53081.1 - 0.00038 20.0 0.1 0.00073 19.1 0.1 1.4 1 0 0 1 1 1 1 HDOD domain DUF3391 PF11871.8 EMT53081.1 - 0.01 16.3 0.1 0.032 14.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Gp_dh_C PF02800.20 EMT53082.1 - 1.5e-68 229.3 0.1 2.7e-68 228.5 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EMT53082.1 - 2.5e-38 130.5 1.8 4.1e-38 129.8 0.0 2.3 3 1 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EMT53082.1 - 0.0014 18.7 0.3 0.0088 16.2 0.0 2.4 1 1 1 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EMT53082.1 - 0.038 13.4 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyoxalase PF00903.25 EMT53083.1 - 1.9e-18 66.9 0.0 2.2e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMT53083.1 - 2.8e-06 27.6 0.0 3.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EMT53083.1 - 1.9e-05 25.4 0.0 2.3e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain TPR_7 PF13176.6 EMT53083.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyoxalase_3 PF13468.6 EMT53083.1 - 0.09 12.9 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EMT53083.1 - 0.18 11.7 0.4 19 5.2 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain Lyase_1 PF00206.20 EMT53084.1 - 5.7e-85 285.5 0.0 7.9e-85 285.0 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EMT53084.1 - 2.1e-26 92.5 0.0 5.4e-26 91.1 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal ABC_tran PF00005.27 EMT53085.1 - 2.8e-36 125.0 0.0 4.1e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT53085.1 - 1.4e-11 44.8 0.0 3.9e-05 23.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT53085.1 - 2e-08 33.9 0.1 1.8e-07 30.8 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMT53085.1 - 3.2e-05 23.9 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 EMT53085.1 - 0.00011 22.1 0.0 0.0061 16.3 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EMT53085.1 - 0.00012 21.8 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT53085.1 - 0.0002 21.6 0.0 0.00052 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMT53085.1 - 0.00037 21.1 0.1 0.0011 19.4 0.0 1.8 3 0 0 3 3 2 1 AAA domain ABC_ATPase PF09818.9 EMT53085.1 - 0.0013 17.6 0.1 0.79 8.4 0.0 2.8 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 EMT53085.1 - 0.0013 19.1 0.0 0.0019 18.6 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EMT53085.1 - 0.0049 16.8 0.0 0.096 12.6 0.0 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 EMT53085.1 - 0.0067 16.2 0.1 0.015 15.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EMT53085.1 - 0.0074 16.2 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_13 PF13166.6 EMT53085.1 - 0.015 14.0 0.0 0.87 8.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EMT53085.1 - 0.017 15.3 0.4 0.32 11.2 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EMT53085.1 - 0.02 14.6 0.4 0.099 12.4 0.1 2.2 2 1 1 3 3 3 0 AAA domain AAA PF00004.29 EMT53085.1 - 0.036 14.5 0.1 0.42 11.0 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EMT53085.1 - 0.037 14.1 0.0 0.097 12.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EMT53085.1 - 0.049 12.8 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EMT53085.1 - 0.056 14.0 0.0 0.13 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMT53085.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMT53085.1 - 0.093 12.3 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EMT53085.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_PrkA PF08298.11 EMT53085.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain cobW PF02492.19 EMT53085.1 - 0.11 12.1 0.1 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 EMT53085.1 - 0.14 11.7 0.0 0.42 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMT53085.1 - 0.15 12.3 0.0 0.39 10.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain BPD_transp_1 PF00528.22 EMT53086.1 - 6.5e-25 87.9 16.3 7.7e-25 87.7 16.3 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF2626 PF11117.8 EMT53086.1 - 8.7 7.1 11.4 2 9.2 0.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2626) SBP_bac_3 PF00497.20 EMT53087.1 - 7.7e-57 192.3 1.9 8.8e-57 192.1 1.9 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EMT53087.1 - 2.6e-09 37.3 0.1 3.3e-08 33.7 0.1 2.2 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Phosphonate-bd PF12974.7 EMT53087.1 - 1e-06 28.6 1.1 7.1e-06 25.8 1.1 2.0 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EMT53087.1 - 0.00027 21.0 0.7 0.00049 20.1 0.7 1.5 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_11 PF13531.6 EMT53087.1 - 0.0029 17.4 0.8 0.0062 16.3 0.8 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SLT PF01464.20 EMT53089.1 - 2.7e-32 110.8 0.0 3.4e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.6 EMT53089.1 - 0.0012 18.1 0.1 0.49 9.6 0.0 2.2 1 1 1 2 2 2 2 Transglycosylase SLT domain Glucosaminidase PF01832.20 EMT53089.1 - 0.015 15.8 0.0 0.024 15.1 0.0 1.6 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Phage_lysozyme2 PF18013.1 EMT53089.1 - 0.14 12.2 0.1 0.25 11.4 0.0 1.5 2 0 0 2 2 2 0 Phage tail lysozyme CoaE PF01121.20 EMT53090.1 - 1.2e-65 220.6 0.6 1.4e-65 220.3 0.6 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EMT53090.1 - 7.8e-05 23.2 0.3 0.00032 21.3 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EMT53090.1 - 8.2e-05 22.9 3.9 0.0023 18.2 3.9 2.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMT53090.1 - 0.00014 22.0 0.0 0.031 14.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain XRN1_D1 PF18332.1 EMT53090.1 - 0.026 14.3 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 Exoribonuclease Xrn1 D1 domain DUF2332 PF10094.9 EMT53090.1 - 0.043 13.3 0.6 0.056 12.9 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) Amidase PF01425.21 EMT53090.1 - 0.062 12.3 0.2 0.12 11.3 0.2 1.5 2 0 0 2 2 2 0 Amidase UPF0004 PF00919.20 EMT53090.1 - 0.1 12.7 0.1 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 dNK PF01712.19 EMT53090.1 - 0.15 11.9 0.2 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase Fapy_DNA_glyco PF01149.24 EMT53091.1 - 2.7e-33 115.1 0.4 4.7e-33 114.3 0.4 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EMT53091.1 - 1.9e-30 104.7 0.1 3.8e-30 103.7 0.0 1.5 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 EMT53091.1 - 4.2e-10 39.3 3.2 7.8e-10 38.4 3.2 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS FbpA PF05833.11 EMT53091.1 - 0.0086 14.9 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Zn_ribbon_SprT PF17283.2 EMT53091.1 - 0.072 13.0 0.8 0.14 12.1 0.8 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 EMT53091.1 - 0.11 12.6 1.1 0.22 11.6 1.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DNA_pol_A PF00476.20 EMT53092.1 - 3.4e-164 546.4 0.1 4e-163 542.8 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 EMT53092.1 - 5e-54 182.5 0.0 1.1e-53 181.4 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 EMT53092.1 - 2.3e-34 117.9 0.2 2.3e-34 117.9 0.2 2.7 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 EMT53092.1 - 0.0017 18.4 0.0 0.098 12.8 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EMT53092.1 - 0.0035 17.9 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain UBA_3 PF09288.10 EMT53092.1 - 0.076 12.8 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Polysacc_deac_2 PF04748.13 EMT53093.1 - 2.3e-74 249.2 0.0 2.7e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase S8_pro-domain PF16470.5 EMT53093.1 - 0.013 16.2 0.0 0.042 14.6 0.0 1.8 2 0 0 2 2 2 0 Peptidase S8 pro-domain Amidase_3 PF01520.18 EMT53094.1 - 5.6e-40 137.3 0.0 6.5e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase EamA PF00892.20 EMT53095.1 - 1.6e-31 109.3 44.3 7.5e-16 58.5 20.5 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EMT53095.1 - 0.013 14.8 6.9 0.75 9.1 1.2 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF2534 PF10749.9 EMT53095.1 - 4.1 7.7 9.5 1.1 9.4 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2534) Metallophos_2 PF12850.7 EMT53096.1 - 3.6e-29 102.1 0.0 4e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EMT53096.1 - 0.00032 21.3 0.6 0.43 11.0 0.1 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Aminotran_4 PF01063.19 EMT53097.1 - 1.3e-36 126.5 0.0 1.6e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV UDPGT PF00201.18 EMT53098.1 - 1.8e-21 76.5 0.0 2e-17 63.2 0.0 2.6 3 0 0 3 3 3 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EMT53098.1 - 2.4e-08 34.1 0.0 4.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 EMT53098.1 - 8.8e-07 29.0 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PadR PF03551.14 EMT53099.1 - 9.1e-13 48.0 0.0 1.9e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family AphA_like PF14557.6 EMT53099.1 - 0.05 13.3 0.0 0.082 12.6 0.0 1.4 1 1 0 1 1 1 0 Putative AphA-like transcriptional regulator MFS_1 PF07690.16 EMT53100.1 - 1.8e-53 181.7 50.1 1.8e-53 181.7 50.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 EMT53100.1 - 5.6e-05 21.7 7.0 5.6e-05 21.7 7.0 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector HlyD_D23 PF16576.5 EMT53101.1 - 1e-30 106.5 10.9 1.1e-26 93.4 0.4 2.3 1 1 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EMT53101.1 - 6e-26 91.2 9.2 3.1e-21 76.1 1.2 3.3 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EMT53101.1 - 6.4e-15 54.7 2.7 6.4e-15 54.7 2.7 4.1 4 1 0 4 4 4 2 Biotin-lipoyl like HlyD PF00529.20 EMT53101.1 - 4.3e-06 26.5 0.7 3e-05 23.8 0.7 2.6 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 EMT53101.1 - 3.2e-05 23.7 1.2 0.0036 17.1 0.6 3.0 2 0 0 2 2 2 1 Biotin-requiring enzyme SHOCT PF09851.9 EMT53101.1 - 0.00047 19.8 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 Short C-terminal domain HlyD_2 PF12700.7 EMT53101.1 - 0.0016 17.2 7.3 0.047 12.4 7.3 2.3 1 1 0 1 1 1 1 HlyD family secretion protein YqfD PF06898.11 EMT53101.1 - 0.0052 15.7 0.6 0.0082 15.0 0.6 1.3 1 0 0 1 1 1 1 Putative stage IV sporulation protein YqfD OEP PF02321.18 EMT53101.1 - 0.007 16.2 24.5 0.012 15.4 16.9 3.1 2 1 1 3 3 3 1 Outer membrane efflux protein Fez1 PF06818.15 EMT53101.1 - 0.013 15.9 7.3 0.021 15.3 7.3 1.2 1 0 0 1 1 1 0 Fez1 QRPTase_N PF02749.16 EMT53101.1 - 0.038 14.0 0.4 0.16 12.1 0.2 2.2 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain PASTA PF03793.19 EMT53101.1 - 0.12 12.3 4.1 0.2 11.5 0.3 3.3 3 0 0 3 3 3 0 PASTA domain ABC_tran_CTD PF16326.5 EMT53101.1 - 1.8 8.9 15.7 4 7.8 4.5 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF2564 PF10819.8 EMT53101.1 - 2.1 8.8 16.1 2.7 8.4 1.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) HlyD_D23 PF16576.5 EMT53102.1 - 6e-17 61.6 0.2 1.1e-15 57.5 0.1 2.1 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EMT53102.1 - 4.1e-15 56.4 1.1 9.8e-15 55.2 0.3 2.0 2 1 0 2 2 2 1 HlyD family secretion protein HlyD PF00529.20 EMT53102.1 - 4.3e-06 26.5 0.0 7.5e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 EMT53102.1 - 1.3e-05 24.9 2.0 0.037 13.9 0.5 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_2 PF12700.7 EMT53102.1 - 2e-05 23.6 0.0 2.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 HlyD family secretion protein CSD2 PF17876.1 EMT53102.1 - 0.00011 22.3 0.1 0.33 11.2 0.0 2.6 1 1 1 2 2 2 2 Cold shock domain Biotin_lipoyl PF00364.22 EMT53102.1 - 0.00025 20.8 0.5 0.26 11.2 0.1 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme RnfC_N PF13375.6 EMT53102.1 - 0.0013 18.6 1.0 0.058 13.4 0.1 3.0 2 1 1 3 3 3 1 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 EMT53102.1 - 0.035 14.3 1.1 3.4 7.9 0.2 2.9 1 1 0 2 2 2 0 Peptidase family M23 DUF4307 PF14155.6 EMT53102.1 - 0.041 13.7 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) MarR PF01047.22 EMT53103.1 - 9.5e-13 47.9 1.8 1.5e-12 47.3 0.3 2.1 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 EMT53103.1 - 2.4e-12 47.2 0.8 7.7e-12 45.5 0.5 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 EMT53103.1 - 9.5e-11 41.4 0.3 2e-10 40.4 0.2 1.6 2 0 0 2 2 1 1 MarR family HTH_29 PF13551.6 EMT53103.1 - 2.3e-05 24.3 0.2 5e-05 23.2 0.1 1.6 2 0 0 2 2 1 1 Winged helix-turn helix HTH_24 PF13412.6 EMT53103.1 - 8.8e-05 22.0 0.2 0.00054 19.5 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 EMT53103.1 - 0.00015 21.5 0.1 0.00034 20.4 0.1 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 EMT53103.1 - 0.00021 21.1 0.1 0.00046 20.0 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 EMT53103.1 - 0.00033 20.7 0.1 0.0011 19.0 0.0 1.9 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 EMT53103.1 - 0.00097 19.0 0.5 0.0025 17.6 0.2 1.8 2 0 0 2 2 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EMT53103.1 - 0.00099 19.1 1.0 0.0015 18.6 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Rrf2 PF02082.20 EMT53103.1 - 0.0016 18.8 0.2 0.0091 16.3 0.0 2.2 3 0 0 3 3 3 1 Transcriptional regulator HTH_23 PF13384.6 EMT53103.1 - 0.0018 18.0 0.0 0.0051 16.6 0.0 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 EMT53103.1 - 0.0068 16.4 0.8 0.014 15.4 0.8 1.7 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain Penicillinase_R PF03965.16 EMT53103.1 - 0.0072 16.7 0.1 0.014 15.7 0.1 1.7 1 1 0 1 1 1 1 Penicillinase repressor FtsK_gamma PF09397.10 EMT53103.1 - 0.0092 15.8 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 Ftsk gamma domain HTH_34 PF13601.6 EMT53103.1 - 0.025 14.8 0.0 0.058 13.6 0.0 1.6 2 0 0 2 2 1 0 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 EMT53103.1 - 0.028 14.6 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_45 PF14947.6 EMT53103.1 - 0.034 14.1 0.0 0.091 12.8 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix HAMP PF00672.25 EMT53103.1 - 0.046 14.1 0.0 3.2 8.2 0.0 2.7 2 1 0 2 2 2 0 HAMP domain HTH_1 PF00126.27 EMT53103.1 - 0.054 13.5 0.2 0.19 11.7 0.0 2.1 2 1 1 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family GntR PF00392.21 EMT53103.1 - 0.073 12.7 0.2 0.19 11.4 0.2 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_Tnp_ISL3 PF13542.6 EMT53103.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MerR PF00376.23 EMT53103.1 - 0.088 12.6 0.7 0.79 9.5 0.7 2.3 1 1 0 1 1 1 0 MerR family regulatory protein DprA_WH PF17782.1 EMT53103.1 - 0.092 12.9 0.9 0.13 12.4 0.2 1.6 2 0 0 2 2 2 0 DprA winged helix domain HopW1-1 PF15457.6 EMT53103.1 - 0.12 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA VanW PF04294.13 EMT53104.1 - 7e-52 174.5 0.0 1.1e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 VanW like protein PG_binding_4 PF12229.8 EMT53104.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain MeaB PF03308.16 EMT53105.1 - 0.00064 18.8 0.0 0.015 14.3 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EMT53105.1 - 0.0012 19.1 0.1 0.01 16.1 0.0 2.6 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 EMT53105.1 - 0.0021 17.8 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EMT53105.1 - 0.0029 18.1 0.0 0.01 16.4 0.0 1.7 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 EMT53105.1 - 0.008 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.6 EMT53105.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 EMT53105.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 EMT53105.1 - 0.012 16.1 0.3 0.13 12.9 0.0 2.6 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EMT53105.1 - 0.014 15.3 0.0 0.049 13.6 0.0 1.9 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.18 EMT53105.1 - 0.029 13.7 0.0 0.087 12.2 0.0 1.8 1 1 1 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.9 EMT53105.1 - 0.029 13.6 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EMT53105.1 - 0.03 14.7 0.5 0.18 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 EMT53105.1 - 0.036 13.0 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 EMT53105.1 - 0.039 14.0 0.0 0.098 12.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.6 EMT53105.1 - 0.048 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EMT53105.1 - 0.058 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 EMT53105.1 - 0.08 13.4 0.4 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EMT53105.1 - 0.08 12.2 0.0 0.21 10.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 EMT53105.1 - 0.082 13.1 0.3 0.2 11.8 0.1 1.9 2 1 0 2 2 1 0 AAA domain Ploopntkinase3 PF18751.1 EMT53105.1 - 0.11 12.4 0.0 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 cobW PF02492.19 EMT53105.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EMT53105.1 - 0.21 12.0 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF349 PF03993.12 EMT53105.1 - 0.31 11.4 2.0 0.75 10.1 0.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) PhoU PF01895.19 EMT53106.1 - 4.9e-46 155.1 3.4 2.8e-23 82.2 0.1 2.1 2 0 0 2 2 2 2 PhoU domain DUF5344 PF17279.2 EMT53106.1 - 0.049 14.2 0.3 1.3 9.7 0.0 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5344) HATPase_c PF02518.26 EMT53107.1 - 1.7e-32 112.2 0.6 5.3e-32 110.7 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT53107.1 - 1.1e-19 70.2 0.6 4e-19 68.4 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EMT53107.1 - 5.8e-12 45.8 0.1 1.5e-11 44.5 0.1 1.8 1 0 0 1 1 1 1 HAMP domain PAS PF00989.25 EMT53107.1 - 6.1e-11 42.3 0.1 5.1e-10 39.3 0.0 2.6 2 1 0 2 2 2 1 PAS fold sCache_like PF16736.5 EMT53107.1 - 7.3e-11 42.2 2.2 2.4e-10 40.5 0.0 2.7 3 0 0 3 3 3 1 Single Cache-like PAS_4 PF08448.10 EMT53107.1 - 3.8e-10 40.0 0.0 1.5e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold dCache_1 PF02743.18 EMT53107.1 - 1.3e-09 38.2 0.1 1.6e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Cache domain PAS_9 PF13426.7 EMT53107.1 - 1.6e-08 34.8 0.0 9.9e-08 32.2 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 EMT53107.1 - 8.1e-07 28.9 0.0 2.4e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 EMT53107.1 - 7.6e-05 22.7 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_10 PF13596.6 EMT53107.1 - 0.00027 21.5 0.0 0.0011 19.6 0.0 2.1 2 0 0 2 2 1 1 PAS domain HATPase_c_3 PF13589.6 EMT53107.1 - 0.00031 20.6 0.0 0.00076 19.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EMT53107.1 - 0.00064 19.6 0.0 0.0022 17.8 0.0 2.0 1 0 0 1 1 1 1 GHKL domain PAS_7 PF12860.7 EMT53107.1 - 0.00075 19.6 0.0 0.016 15.3 0.0 3.0 1 1 0 1 1 1 1 PAS fold PocR PF10114.9 EMT53107.1 - 0.063 13.1 0.2 0.73 9.6 0.0 2.4 2 0 0 2 2 2 0 Sensory domain found in PocR MAP65_ASE1 PF03999.12 EMT53107.1 - 0.13 11.0 3.4 4.2 5.9 0.1 3.0 3 0 0 3 3 3 0 Microtubule associated protein (MAP65/ASE1 family) Trans_reg_C PF00486.28 EMT53108.1 - 3.9e-32 110.2 0.2 6.9e-32 109.4 0.2 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 EMT53108.1 - 1.2e-31 109.1 0.3 2.3e-31 108.3 0.3 1.4 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 EMT53108.1 - 0.062 13.7 0.0 0.097 13.0 0.0 1.4 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ OKR_DC_1_N PF03709.15 EMT53108.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Ldh_1_N PF00056.23 EMT53109.1 - 8e-43 145.9 0.1 1.1e-42 145.5 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EMT53109.1 - 4e-28 98.4 0.0 6.6e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 EMT53109.1 - 2.5e-05 23.9 1.0 0.00011 21.8 1.0 1.9 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.16 EMT53109.1 - 3e-05 23.6 0.3 0.0059 16.2 0.1 2.5 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase DAO PF01266.24 EMT53109.1 - 0.00024 20.8 0.5 0.0011 18.7 0.2 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EMT53109.1 - 0.0059 16.5 0.4 0.04 13.8 0.4 2.2 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EMT53109.1 - 0.0099 15.1 0.1 0.02 14.1 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMT53109.1 - 0.024 14.9 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF1188 PF06690.11 EMT53109.1 - 0.052 13.1 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Iso_dh PF00180.20 EMT53110.1 - 6.2e-120 400.5 0.0 7.5e-120 400.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SBP_bac_5 PF00496.22 EMT53110.1 - 0.03 13.3 0.2 0.046 12.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Citrate_synt PF00285.21 EMT53111.1 - 8.9e-129 429.7 0.1 1e-128 429.5 0.1 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain TetR_C_14 PF17754.1 EMT53111.1 - 0.067 13.1 0.6 0.16 11.9 0.6 1.7 1 0 0 1 1 1 0 MftR C-terminal domain AI-2E_transport PF01594.16 EMT53112.1 - 1.4e-60 205.2 35.0 1.9e-60 204.7 35.0 1.1 1 0 0 1 1 1 1 AI-2E family transporter Tom7 PF08038.12 EMT53112.1 - 8.9 6.1 7.5 8.3 6.2 0.7 2.7 2 0 0 2 2 2 0 TOM7 family PsbI PF02532.14 EMT53112.1 - 9.4 6.3 7.6 1.7 8.7 2.3 2.7 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) FxsA PF04186.13 EMT53113.1 - 2.8e-35 120.7 9.2 3.4e-35 120.4 9.2 1.0 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein 4HBT PF03061.22 EMT53114.1 - 6.1e-16 58.5 0.0 9.6e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 EMT53114.1 - 3.3e-12 47.0 0.0 3.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 EMT53114.1 - 1.9e-06 27.4 0.6 9.4e-06 25.1 0.6 1.8 1 1 0 1 1 1 1 Acyl-ACP thioesterase NUDIX PF00293.28 EMT53115.1 - 2e-16 60.2 0.1 3.9e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain NIPSNAP PF07978.13 EMT53115.1 - 5.3e-14 52.3 0.2 1.1e-13 51.3 0.2 1.5 1 0 0 1 1 1 1 NIPSNAP PKHD_C PF18331.1 EMT53115.1 - 0.00097 19.2 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 PKHD-type hydroxylase C-terminal domain Maf PF02545.14 EMT53115.1 - 0.024 14.5 0.0 0.071 13.0 0.0 1.6 2 0 0 2 2 2 0 Maf-like protein HSCB_C PF07743.13 EMT53115.1 - 0.064 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain RNR_Alpha PF17975.1 EMT53116.1 - 1.4e-28 99.4 0.0 1.1e-26 93.2 0.0 2.9 2 0 0 2 2 2 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 EMT53116.1 - 4.6e-16 58.5 0.0 7.7e-14 51.1 0.0 3.2 3 0 0 3 3 3 2 Ribonucleotide reductase, barrel domain PK PF00224.21 EMT53118.1 - 5.3e-156 518.8 8.1 9.8e-156 518.0 8.1 1.4 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EMT53118.1 - 7.5e-37 126.1 1.0 7.5e-37 126.1 1.0 2.3 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain PEP-utilizers PF00391.23 EMT53118.1 - 1.5e-20 72.7 1.6 1.5e-20 72.7 1.6 2.7 3 0 0 3 3 3 1 PEP-utilising enzyme, mobile domain HpcH_HpaI PF03328.14 EMT53118.1 - 1.6e-05 24.2 1.7 2e-05 23.8 0.3 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EMT53118.1 - 0.006 15.6 0.4 0.006 15.6 0.4 2.9 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain IF2_N PF04760.15 EMT53118.1 - 0.0096 15.7 0.0 0.037 13.8 0.0 2.1 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region DRTGG PF07085.12 EMT53118.1 - 0.033 14.0 3.4 0.063 13.1 0.5 3.1 3 1 0 3 3 3 0 DRTGG domain PFK PF00365.20 EMT53119.1 - 9.1e-113 376.3 5.7 1.1e-112 376.1 5.7 1.0 1 0 0 1 1 1 1 Phosphofructokinase Peripla_BP_1 PF00532.21 EMT53119.1 - 0.0092 15.4 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family DAGK_cat PF00781.24 EMT53119.1 - 0.027 14.1 0.6 0.13 11.8 0.1 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EMT53119.1 - 0.047 12.9 0.1 0.078 12.2 0.1 1.3 1 0 0 1 1 1 0 ATP-NAD kinase ACCA PF03255.14 EMT53120.1 - 1.8e-66 222.5 0.0 2.6e-66 221.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 EMT53120.1 - 2.4e-16 59.5 0.2 3e-16 59.1 0.2 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EMT53120.1 - 1.1e-05 25.0 0.1 1.4e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) Carboxyl_trans PF01039.22 EMT53121.1 - 9.6e-15 54.2 0.1 1.2e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain zf-ACC PF17848.1 EMT53121.1 - 3.1e-08 33.5 3.7 1.1e-07 31.8 3.6 1.9 2 0 0 2 2 2 1 Acetyl-coA carboxylase zinc finger domain Zn_ribbon_SprT PF17283.2 EMT53121.1 - 0.027 14.4 1.9 0.04 13.8 1.9 1.3 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-ribbon_3 PF13248.6 EMT53121.1 - 0.028 13.8 0.2 0.062 12.7 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.9 EMT53121.1 - 0.04 14.0 1.9 0.77 9.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.11 EMT53121.1 - 0.071 13.0 1.8 0.14 12.1 1.8 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 EMT53121.1 - 0.17 11.9 1.4 0.29 11.1 1.4 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 EMT53121.1 - 0.39 10.7 5.5 0.12 12.3 1.2 2.2 2 0 0 2 2 2 0 Nudix N-terminal Flavodoxin_5 PF12724.7 EMT53122.1 - 0.009 16.2 0.0 0.01 16.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain YscJ_FliF PF01514.17 EMT53122.1 - 0.026 14.2 0.0 0.027 14.1 0.0 1.0 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family FCD PF07729.12 EMT53123.1 - 1.1e-28 100.1 10.9 1.9e-28 99.4 10.9 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EMT53123.1 - 8.2e-18 63.8 0.9 8.2e-18 63.8 0.9 2.5 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family FadR_C PF07840.12 EMT53123.1 - 0.00017 21.5 0.0 0.00023 21.1 0.0 1.1 1 0 0 1 1 1 1 FadR C-terminal domain TrmB PF01978.19 EMT53123.1 - 0.00019 21.2 0.0 0.0005 19.9 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 EMT53123.1 - 0.0009 19.2 0.2 0.002 18.1 0.2 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 EMT53123.1 - 0.0022 17.8 1.0 0.0061 16.3 0.2 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_CodY PF08222.11 EMT53123.1 - 0.0046 16.5 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 CodY helix-turn-helix domain HTH_20 PF12840.7 EMT53123.1 - 0.0064 16.5 0.2 0.021 14.9 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EMT53123.1 - 0.0081 16.0 0.7 0.021 14.7 0.2 1.9 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 EMT53123.1 - 0.012 15.2 0.4 0.053 13.1 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 EMT53123.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 EMT53123.1 - 0.018 15.4 0.1 0.037 14.4 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_41 PF14502.6 EMT53123.1 - 0.025 14.2 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.6 EMT53123.1 - 0.028 14.9 0.4 0.086 13.4 0.1 2.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain LexA_DNA_bind PF01726.16 EMT53123.1 - 0.046 13.5 0.5 0.12 12.1 0.1 2.0 2 0 0 2 2 1 0 LexA DNA binding domain HTH_5 PF01022.20 EMT53123.1 - 0.048 13.5 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 EMT53123.1 - 0.071 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DprA_WH PF17782.1 EMT53123.1 - 0.15 12.2 2.2 0.41 10.8 2.2 1.8 1 0 0 1 1 1 0 DprA winged helix domain malic PF00390.19 EMT53124.1 - 6.9e-33 114.0 0.1 1.6e-30 106.3 0.1 2.5 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 EMT53124.1 - 3e-24 85.7 10.0 2.9e-23 82.5 10.0 2.2 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain ELFV_dehydrog PF00208.21 EMT53124.1 - 0.00098 18.9 1.5 0.0012 18.7 0.2 1.8 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.21 EMT53124.1 - 0.026 13.9 1.0 0.026 13.9 1.0 2.0 2 0 0 2 2 2 0 ThiF family SWIRM-assoc_3 PF16498.5 EMT53124.1 - 4.5 7.6 8.6 1.4 9.2 5.2 1.9 2 0 0 2 2 2 0 SWIRM-associated domain at the C-terminal DNA_pol3_alpha PF07733.12 EMT53125.1 - 8.4e-104 346.8 0.0 1.4e-103 346.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 EMT53125.1 - 3.1e-61 205.6 0.0 7.3e-61 204.3 0.0 1.7 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 EMT53125.1 - 6.6e-53 179.4 0.0 1.4e-52 178.3 0.0 1.6 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 EMT53125.1 - 1.4e-28 98.9 0.0 3.5e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 EMT53125.1 - 5.9e-09 35.8 0.1 1.3e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EMT53125.1 - 0.0063 16.7 0.1 0.036 14.3 0.1 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CcmE PF03100.15 EMT53125.1 - 0.0079 16.2 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 CcmE YtpI PF14007.6 EMT53126.1 - 2.6e-21 75.5 3.0 3e-21 75.3 3.0 1.0 1 0 0 1 1 1 1 YtpI-like protein SLATT_6 PF18169.1 EMT53126.1 - 0.051 13.2 0.2 0.059 13.0 0.2 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Intg_mem_TP0381 PF09529.10 EMT53126.1 - 0.061 12.8 1.5 0.076 12.5 1.5 1.3 1 1 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) DUF202 PF02656.15 EMT53126.1 - 0.57 10.7 4.8 0.11 13.0 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DRTGG PF07085.12 EMT53127.1 - 2.6e-29 101.1 0.1 5.3e-29 100.1 0.1 1.5 1 0 0 1 1 1 1 DRTGG domain CBS PF00571.28 EMT53127.1 - 9e-16 58.1 0.5 7.3e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain GntR PF00392.21 EMT53127.1 - 9.4e-06 25.2 0.0 3.4e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EMT53127.1 - 2e-05 24.0 0.7 5.7e-05 22.6 0.0 2.2 3 0 0 3 3 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 EMT53127.1 - 5.3e-05 23.1 0.2 0.00015 21.7 0.2 1.9 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 EMT53127.1 - 0.00023 20.9 0.0 0.0007 19.3 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain 4HBT PF03061.22 EMT53127.1 - 0.00029 21.1 0.0 0.00067 20.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily HTH_29 PF13551.6 EMT53127.1 - 0.00045 20.2 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_36 PF13730.6 EMT53127.1 - 0.0022 17.9 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EMT53127.1 - 0.0024 18.0 0.0 0.0067 16.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 EMT53127.1 - 0.0026 17.5 0.1 0.0067 16.2 0.1 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain PucR PF07905.11 EMT53127.1 - 0.0041 17.4 0.0 0.034 14.4 0.0 2.2 1 1 0 1 1 1 1 Purine catabolism regulatory protein-like family 4HBT_3 PF13622.6 EMT53127.1 - 0.0046 17.3 0.1 0.0072 16.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Fe_dep_repress PF01325.19 EMT53127.1 - 0.007 16.5 0.0 0.025 14.8 0.0 1.9 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 EMT53127.1 - 0.0091 15.9 0.1 0.027 14.4 0.0 1.8 2 0 0 2 2 1 1 MarR family Amdase PF17645.1 EMT53127.1 - 0.01 15.4 0.4 0.062 12.9 0.0 2.3 3 0 0 3 3 3 0 Arylmalonate decarboxylase TrmB PF01978.19 EMT53127.1 - 0.022 14.6 0.7 0.054 13.4 0.2 1.9 2 0 0 2 2 1 0 Sugar-specific transcriptional regulator TrmB HTH_Tnp_ISL3 PF13542.6 EMT53127.1 - 0.054 12.9 0.0 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 EMT53127.1 - 0.06 13.1 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_22 PF13309.6 EMT53127.1 - 0.069 13.2 0.0 0.25 11.5 0.0 2.0 1 0 0 1 1 1 0 HTH domain HTH_6 PF01418.17 EMT53127.1 - 0.096 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Hpr_kinase_N PF02603.16 EMT53127.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 HPr Serine kinase N terminus HTH_IclR PF09339.10 EMT53127.1 - 0.11 12.3 0.0 0.98 9.3 0.0 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain 4HBT_2 PF13279.6 EMT53127.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase-like superfamily HTH_AsnC-type PF13404.6 EMT53127.1 - 0.13 12.1 0.0 0.41 10.5 0.0 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 EMT53127.1 - 0.19 11.4 0.3 0.55 9.9 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 DUF445 PF04286.12 EMT53128.1 - 2.3e-64 218.5 0.0 2.7e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF445) MscL PF01741.18 EMT53128.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.7 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL Spo0A_C PF08769.11 EMT53128.1 - 0.13 12.4 0.0 0.8 9.8 0.0 2.1 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal ATPgrasp_YheCD PF14398.6 EMT53129.1 - 1.1e-79 267.3 0.0 1.4e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EMT53129.1 - 1.6e-05 24.3 0.0 0.0046 16.2 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp TTL PF03133.15 EMT53129.1 - 6.7e-05 22.2 0.0 0.0048 16.1 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family GSH-S_ATP PF02955.16 EMT53129.1 - 0.0015 17.9 0.0 0.0052 16.2 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_YheCD PF14398.6 EMT53130.1 - 5.5e-80 268.3 0.0 6.5e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EMT53130.1 - 4.2e-08 32.8 0.0 0.0045 16.3 0.0 2.5 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 EMT53130.1 - 0.00039 20.1 0.0 0.081 12.5 0.0 3.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 EMT53130.1 - 0.0021 17.5 0.1 0.045 13.2 0.1 2.4 1 1 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain TTL PF03133.15 EMT53130.1 - 0.0087 15.2 0.0 2.3 7.3 0.0 3.0 3 0 0 3 3 3 1 Tubulin-tyrosine ligase family ATP-grasp_3 PF02655.14 EMT53130.1 - 0.025 14.6 0.0 3.9 7.5 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EMT53130.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 EMT53130.1 - 0.14 11.8 0.0 5.7 6.5 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_YheCD PF14398.6 EMT53131.1 - 3.3e-83 278.9 0.0 4.8e-83 278.3 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EMT53131.1 - 6.7e-06 25.6 0.0 0.033 13.4 0.0 2.5 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp PEX-2N PF09263.10 EMT53131.1 - 0.0045 17.3 0.0 0.0098 16.2 0.0 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal CDC48_N PF02359.18 EMT53131.1 - 0.07 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain ATPgrasp_YheCD PF14398.6 EMT53132.1 - 2.7e-76 256.2 0.2 3.3e-76 255.9 0.2 1.1 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EMT53132.1 - 1.5e-07 31.0 0.1 0.0022 17.3 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 EMT53132.1 - 0.0025 17.3 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain Acetyltransf_10 PF13673.7 EMT53133.1 - 2.2e-07 30.9 0.0 2.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT53133.1 - 7.4e-07 29.4 0.1 9.5e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT53133.1 - 7.5e-05 23.1 0.0 0.00012 22.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMT53133.1 - 0.00097 19.8 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT53133.1 - 0.0033 17.4 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein SASP_gamma PF04259.14 EMT53134.1 - 0.01 16.3 34.1 0.059 13.9 8.1 4.4 1 1 3 4 4 4 0 Small, acid-soluble spore protein, gamma-type Qn_am_d_aIV PF09100.10 EMT53134.1 - 0.013 15.3 11.7 2.2 8.1 0.2 4.7 3 2 2 5 5 5 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV PTS_EIIA_1 PF00358.20 EMT53134.1 - 0.15 11.8 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF5045 PF16464.5 EMT53135.1 - 0.005 17.1 0.1 0.01 16.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5045) UCR_14kD PF02271.16 EMT53135.1 - 0.031 14.2 0.3 0.18 11.8 0.1 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit AhpC-TSA PF00578.21 EMT53136.1 - 3.9e-40 136.6 0.0 4.7e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMT53136.1 - 6.8e-15 55.0 0.0 8.1e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EMT53136.1 - 0.00078 19.2 0.1 0.0017 18.1 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EMT53136.1 - 0.037 13.9 0.1 0.069 13.1 0.1 1.4 1 0 0 1 1 1 0 SCO1/SenC Glutaredoxin PF00462.24 EMT53137.1 - 6.6e-15 55.1 0.0 8.8e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EMT53137.1 - 0.0013 19.1 0.0 0.0013 19.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 EMT53137.1 - 0.0021 18.1 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 EMT53137.1 - 0.0095 16.4 0.1 0.013 16.0 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain MSV199 PF10553.9 EMT53137.1 - 0.06 13.6 0.0 0.066 13.5 0.0 1.0 1 0 0 1 1 1 0 MSV199 domain Thioredoxin_4 PF13462.6 EMT53137.1 - 0.13 12.4 0.1 11 6.1 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin Pyr_redox_2 PF07992.14 EMT53138.1 - 1.5e-34 119.6 1.8 2.4e-34 118.9 1.8 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT53138.1 - 7.3e-21 74.7 0.2 1e-14 54.5 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMT53138.1 - 1.7e-09 37.3 4.0 1.2e-06 27.9 0.7 3.2 3 1 1 4 4 4 2 FAD binding domain DAO PF01266.24 EMT53138.1 - 3.6e-09 36.7 2.5 0.00031 20.5 0.9 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EMT53138.1 - 4.8e-09 35.4 2.7 1.1e-05 24.4 0.2 2.7 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 EMT53138.1 - 5.1e-09 35.7 5.0 4.4e-05 22.8 0.7 3.0 2 1 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox PF00070.27 EMT53138.1 - 2.7e-07 31.1 2.1 0.0044 17.5 0.1 3.9 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMT53138.1 - 1e-05 25.6 0.1 2.1e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMT53138.1 - 1.7e-05 24.4 0.9 1.7e-05 24.4 0.9 3.3 3 1 0 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMT53138.1 - 3.9e-05 22.9 0.6 0.053 12.6 0.4 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 EMT53138.1 - 9e-05 21.8 0.3 0.00035 19.9 0.2 2.0 2 0 0 2 2 2 1 Thi4 family Catalase_C PF18011.1 EMT53138.1 - 9.1e-05 22.1 0.4 0.00027 20.6 0.0 2.0 3 1 0 3 3 3 1 C-terminal domain found in long catalases FAD_binding_3 PF01494.19 EMT53138.1 - 0.00046 19.5 0.7 0.0031 16.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 EMT53138.1 - 0.0007 18.6 0.7 0.47 9.2 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_7 PF13241.6 EMT53138.1 - 0.0034 17.8 1.7 1.9 9.0 0.5 2.8 2 1 0 2 2 2 2 Putative NAD(P)-binding Band_7 PF01145.25 EMT53138.1 - 0.0045 17.0 0.0 0.5 10.4 0.0 2.2 2 0 0 2 2 2 1 SPFH domain / Band 7 family TrkA_N PF02254.18 EMT53138.1 - 0.011 15.9 1.0 0.84 9.9 0.0 3.2 2 1 2 4 4 4 0 TrkA-N domain NAD_binding_9 PF13454.6 EMT53138.1 - 0.013 15.5 0.9 2.4 8.1 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 EMT53138.1 - 0.12 11.4 0.0 2.6 7.1 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Cation_efflux PF01545.21 EMT53139.1 - 7.4e-47 159.7 23.3 9.1e-47 159.4 23.3 1.1 1 0 0 1 1 1 1 Cation efflux family SUR7 PF06687.12 EMT53139.1 - 0.00037 20.2 2.1 0.00037 20.2 2.1 2.0 1 1 1 2 2 2 1 SUR7/PalI family ZT_dimer PF16916.5 EMT53139.1 - 0.096 12.8 1.1 0.26 11.4 1.1 1.8 1 1 0 1 1 1 0 Dimerisation domain of Zinc Transporter DUF2663 PF10864.8 EMT53139.1 - 0.3 11.5 2.4 0.73 10.2 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) DUF2070 PF09843.9 EMT53139.1 - 0.68 8.1 14.9 3.5 5.8 14.3 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1361 PF07099.11 EMT53139.1 - 7.5 6.5 10.9 38 4.2 0.6 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1361) Glyoxalase PF00903.25 EMT53140.1 - 1.5e-06 28.4 0.2 1.1e-05 25.6 0.2 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Na_H_antiporter PF03553.14 EMT53141.1 - 3.8e-58 197.1 41.7 1.5e-50 172.2 10.1 2.0 1 1 1 2 2 2 2 Na+/H+ antiporter family GGDEF PF00990.21 EMT53142.1 - 5e-35 120.6 0.0 1e-34 119.6 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GAF_3 PF13492.6 EMT53142.1 - 1e-13 51.7 0.0 2.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EMT53142.1 - 6e-13 49.3 0.0 1.6e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EMT53142.1 - 8.2e-09 36.2 0.0 1.6e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain DALR_1 PF05746.15 EMT53142.1 - 0.11 12.7 0.1 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 DALR anticodon binding domain Med3 PF11593.8 EMT53142.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3870 PF12986.7 EMT53143.1 - 4.2e-16 59.0 0.0 4.9e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3870) SIS_2 PF13580.6 EMT53144.1 - 2.5e-12 47.0 0.1 5e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 EMT53144.1 - 1.3e-09 38.0 0.4 1.8e-08 34.3 0.1 2.4 2 0 0 2 2 2 1 SIS domain ANTAR PF03861.14 EMT53144.1 - 0.00012 21.8 2.5 0.41 10.5 0.2 2.8 2 0 0 2 2 2 2 ANTAR domain UBA_4 PF14555.6 EMT53144.1 - 0.00083 19.1 0.0 1.3 8.9 0.0 2.6 1 1 1 2 2 2 2 UBA-like domain GST_C_2 PF13410.6 EMT53144.1 - 0.026 14.5 0.1 0.058 13.4 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HU-CCDC81_bac_2 PF18175.1 EMT53144.1 - 0.056 13.3 0.0 23 4.9 0.0 3.1 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 RCC1 PF00415.18 EMT53144.1 - 0.074 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat BcrAD_BadFG PF01869.20 EMT53145.1 - 4.9e-34 118.0 0.0 5.8e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 EMT53145.1 - 2.2e-05 24.1 0.0 0.0072 15.8 0.0 2.1 2 0 0 2 2 2 2 ROK family FGGY_N PF00370.21 EMT53145.1 - 0.045 13.3 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain BPD_transp_1 PF00528.22 EMT53146.1 - 3.1e-20 72.7 18.0 3.1e-20 72.7 18.0 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EMT53147.1 - 1.2e-16 61.0 20.3 1.2e-16 61.0 20.3 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_8 PF13416.6 EMT53148.1 - 6.9e-40 137.6 0.4 9.2e-40 137.2 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT53148.1 - 2.8e-39 135.9 5.0 4e-39 135.4 5.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EMT53148.1 - 1.6e-08 34.3 0.0 0.00041 19.8 0.0 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein Beta-lactamase PF00144.24 EMT53149.1 - 8.9e-63 212.5 0.0 1.1e-62 212.2 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase HTH_6 PF01418.17 EMT53150.1 - 6.8e-23 80.4 0.1 2.1e-22 78.9 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 EMT53150.1 - 1.3e-21 76.9 0.5 1.8e-21 76.4 0.5 1.2 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 EMT53150.1 - 2.1e-08 34.3 0.4 2.6e-05 24.2 0.0 2.4 1 1 1 2 2 2 2 SIS domain HTH_36 PF13730.6 EMT53150.1 - 0.0032 17.4 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 EMT53150.1 - 0.0046 16.8 0.1 0.031 14.2 0.0 2.4 3 1 0 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 EMT53150.1 - 0.0059 16.6 0.1 0.024 14.6 0.1 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 EMT53150.1 - 0.02 14.7 0.0 0.073 12.9 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain MarR PF01047.22 EMT53150.1 - 0.029 14.3 0.1 0.15 12.0 0.0 2.2 3 0 0 3 3 3 0 MarR family HTH_29 PF13551.6 EMT53150.1 - 0.03 14.3 0.1 0.1 12.6 0.0 1.9 1 1 1 2 2 2 0 Winged helix-turn helix HTH_17 PF12728.7 EMT53150.1 - 0.05 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 EMT53150.1 - 0.085 12.8 0.1 0.085 12.8 0.1 2.6 4 0 0 4 4 4 0 HTH domain HTH_DeoR PF08220.12 EMT53150.1 - 0.085 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain PQQ_2 PF13360.6 EMT53151.1 - 1.8e-14 53.9 1.5 2.4e-05 24.0 0.0 3.5 1 1 2 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 EMT53151.1 - 1.8e-10 41.0 10.7 0.00016 22.0 0.2 5.3 6 1 0 6 6 6 2 PQQ-like domain PQQ PF01011.21 EMT53151.1 - 7.7e-09 35.1 12.4 0.26 11.3 0.1 7.4 7 0 0 7 7 7 2 PQQ enzyme repeat Tachylectin PF14517.6 EMT53151.1 - 0.0077 15.8 4.5 0.42 10.1 0.2 3.0 2 1 0 2 2 2 2 Tachylectin Arylsulfotrans PF05935.11 EMT53151.1 - 0.017 14.1 2.3 1.4 7.7 0.5 3.8 1 1 3 4 4 4 0 Arylsulfotransferase (ASST) RHS PF03527.14 EMT53151.1 - 0.35 10.6 2.6 35 4.3 0.3 3.6 3 0 0 3 3 3 0 RHS protein DUF3048_C PF17479.2 EMT53151.1 - 0.86 10.0 4.0 2.1 8.8 0.1 3.1 4 1 0 4 4 4 0 Protein of unknown function (DUF3048) C-terminal domain Amidohydro_1 PF01979.20 EMT53152.1 - 7e-72 242.6 0.4 8.2e-72 242.4 0.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMT53152.1 - 8.3e-27 94.8 1.7 4.5e-21 75.9 0.1 2.1 1 1 1 2 2 2 2 Amidohydrolase family TatD_DNase PF01026.21 EMT53152.1 - 0.01 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase MFS_1 PF07690.16 EMT53153.1 - 1.5e-28 99.7 49.8 2.2e-17 63.0 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT53153.1 - 2.1e-17 62.7 30.2 2.6e-17 62.4 30.2 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 EMT53153.1 - 7.6e-08 31.3 32.5 4.1e-06 25.6 11.9 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein Kinocilin PF15033.6 EMT53153.1 - 0.44 10.2 5.0 0.29 10.8 2.2 2.1 1 1 0 1 1 1 0 Kinocilin protein MFS_4 PF06779.14 EMT53153.1 - 0.64 9.2 32.9 0.8 8.9 11.5 2.8 2 2 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Phage_holin_1 PF04531.13 EMT53153.1 - 0.67 10.5 3.4 0.6 10.7 0.1 2.6 3 0 0 3 3 3 0 Bacteriophage holin MerR_1 PF13411.6 EMT53154.1 - 2.3e-14 53.2 0.1 4.9e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 MerR HTH family regulatory protein TipAS PF07739.13 EMT53154.1 - 4.6e-12 46.5 1.3 8.8e-12 45.6 0.8 1.7 1 1 0 1 1 1 1 TipAS antibiotic-recognition domain MerR PF00376.23 EMT53154.1 - 6.6e-12 45.0 0.0 1.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 EMT53154.1 - 3.1e-06 27.6 3.4 3.1e-06 27.6 3.4 2.6 4 0 0 4 4 4 1 MerR, DNA binding MscS_porin PF12795.7 EMT53154.1 - 0.39 10.2 8.3 0.031 13.8 2.5 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TspO_MBR PF03073.15 EMT53155.1 - 3.1e-25 88.8 20.1 3.8e-25 88.5 20.1 1.1 1 0 0 1 1 1 1 TspO/MBR family Ank_4 PF13637.6 EMT53156.1 - 1.5e-29 101.9 0.1 2.7e-07 31.0 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMT53156.1 - 2e-27 95.6 1.2 6.9e-15 55.4 0.0 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMT53156.1 - 1.4e-24 85.8 0.9 1.5e-06 28.3 0.1 4.8 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EMT53156.1 - 2.8e-20 71.8 4.7 2.7e-06 27.6 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EMT53156.1 - 3.1e-17 60.9 0.3 0.0057 17.1 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Nitro_FeMo-Co PF02579.17 EMT53156.1 - 0.024 14.9 1.0 1.2 9.5 0.0 3.0 1 1 1 3 3 3 0 Dinitrogenase iron-molybdenum cofactor LysR_substrate PF03466.20 EMT53157.1 - 7.4e-35 120.2 0.1 1.3e-34 119.4 0.0 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 EMT53157.1 - 1.4e-22 79.4 1.1 4e-22 77.9 0.7 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF3196 PF11428.8 EMT53157.1 - 0.0081 15.7 0.1 0.013 15.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3196) PBP_like_2 PF12849.7 EMT53157.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain Lactamase_B_3 PF13483.6 EMT53158.1 - 6.3e-25 88.0 0.0 8.1e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EMT53158.1 - 1.1e-18 67.5 0.2 1.5e-18 67.1 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMT53158.1 - 2.1e-13 50.7 0.9 3.6e-13 50.0 0.9 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Cyclase PF04199.13 EMT53159.1 - 3e-32 111.7 0.0 4.1e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DUF2642 PF10842.8 EMT53160.1 - 0.0011 18.8 0.1 0.0015 18.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2642) DUF3107 PF11305.8 EMT53160.1 - 0.013 15.7 0.1 0.014 15.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) DUF150_C PF17384.2 EMT53160.1 - 0.033 14.3 1.4 0.047 13.8 1.4 1.4 1 1 0 1 1 1 0 RimP C-terminal SH3 domain RmlD_sub_bind PF04321.17 EMT53161.1 - 2.7e-23 82.5 0.0 8.7e-23 80.8 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EMT53161.1 - 3.2e-19 69.3 0.0 8e-19 68.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMT53161.1 - 2.6e-09 37.2 0.0 1.7e-08 34.6 0.0 2.3 1 1 1 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMT53161.1 - 0.00091 18.7 0.0 0.97 8.8 0.0 2.8 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EMT53161.1 - 0.024 13.8 0.0 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein MerR_1 PF13411.6 EMT53162.1 - 1.2e-07 31.7 0.1 3.5e-07 30.2 0.1 1.8 1 1 0 1 1 1 1 MerR HTH family regulatory protein HTH_28 PF13518.6 EMT53162.1 - 6.7e-05 22.9 0.2 0.00016 21.7 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain DUF3585 PF12130.8 EMT53162.1 - 0.0059 16.7 8.0 0.016 15.3 8.0 1.8 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain Spc29 PF17082.5 EMT53162.1 - 0.018 14.9 4.7 0.042 13.7 4.7 1.7 1 1 0 1 1 1 0 Spindle Pole Component 29 HTH_11 PF08279.12 EMT53162.1 - 0.019 14.9 0.3 0.08 12.9 0.0 2.2 2 1 0 2 2 2 0 HTH domain MerR PF00376.23 EMT53162.1 - 0.029 14.1 0.9 0.11 12.3 0.0 2.4 3 0 0 3 3 3 0 MerR family regulatory protein HTH_17 PF12728.7 EMT53162.1 - 0.03 14.5 0.0 0.073 13.3 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain CCDC-167 PF15188.6 EMT53162.1 - 0.03 14.7 6.7 0.074 13.4 6.7 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Phage_T7_tail PF03906.14 EMT53162.1 - 0.037 13.7 0.1 0.061 13.0 0.1 1.2 1 0 0 1 1 1 0 Phage T7 tail fibre protein HTH_29 PF13551.6 EMT53162.1 - 0.04 14.0 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix CENP-B_N PF04218.13 EMT53162.1 - 0.042 13.5 0.1 0.63 9.7 0.0 2.5 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 EMT53162.1 - 0.045 13.6 0.0 0.22 11.4 0.0 2.2 1 0 0 1 1 1 0 Homeodomain-like domain GntR PF00392.21 EMT53162.1 - 0.057 13.1 0.6 0.8 9.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_3 PF01381.22 EMT53162.1 - 0.059 13.4 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix Phage_terminase PF10668.9 EMT53162.1 - 0.078 13.0 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 1 0 Phage terminase small subunit DUF16 PF01519.16 EMT53162.1 - 0.24 11.9 5.6 0.14 12.7 2.9 1.9 2 1 0 2 2 2 0 Protein of unknown function DUF16 5_nucleotid PF05761.14 EMT53162.1 - 0.52 9.1 7.7 0.21 10.4 5.6 1.4 2 0 0 2 2 2 0 5' nucleotidase family MCU PF04678.13 EMT53162.1 - 0.86 9.7 6.9 1.3 9.1 3.0 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Adaptin_binding PF10199.9 EMT53162.1 - 1.2 9.7 6.4 1.8 9.2 6.4 1.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF3967 PF13152.6 EMT53162.1 - 1.4 8.7 9.4 0.98 9.2 5.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3967) Acetyltransf_11 PF13720.6 EMT53162.1 - 3 8.4 5.1 1.1 9.8 0.2 2.4 2 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 SSF PF00474.17 EMT53163.1 - 8.2e-22 77.6 26.4 1.1e-21 77.2 26.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3311 PF11755.8 EMT53164.1 - 2.7e-22 78.5 2.4 2.9e-22 78.4 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3311) Tetraspanin PF00335.20 EMT53164.1 - 0.031 14.0 1.6 0.032 13.9 1.6 1.0 1 0 0 1 1 1 0 Tetraspanin family TRAM1 PF08390.11 EMT53164.1 - 0.038 13.7 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 TRAM1-like protein TraG_N PF07916.11 EMT53164.1 - 0.35 9.7 5.6 0.4 9.5 5.6 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Peptidase_M20 PF01546.28 EMT53165.1 - 6.2e-34 117.5 1.5 7.8e-34 117.2 1.5 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT53165.1 - 1e-09 38.2 0.0 2.6e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT53165.1 - 0.0042 16.8 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Mrpl_C PF18502.1 EMT53165.1 - 0.036 14.4 0.0 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain Peptidase_M20 PF01546.28 EMT53166.1 - 2.2e-34 119.0 1.1 2.4e-34 118.8 0.3 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT53166.1 - 3.1e-08 33.5 0.0 5.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT53166.1 - 3.6e-08 33.3 0.0 5.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 CPBP PF02517.16 EMT53167.1 - 1.1e-13 51.3 8.2 1.1e-13 51.3 8.2 2.6 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease SdpI PF13630.6 EMT53168.1 - 5.2e-23 80.9 0.8 5.2e-23 80.9 0.8 3.4 2 1 0 2 2 2 1 SdpI/YhfL protein family DUF1648 PF07853.11 EMT53168.1 - 4.8e-14 51.8 0.2 4.8e-14 51.8 0.2 3.4 4 1 1 5 5 5 1 Protein of unknown function (DUF1648) YwiC PF14256.6 EMT53168.1 - 0.00077 19.8 5.7 0.0097 16.2 0.2 2.3 1 1 1 2 2 2 2 YwiC-like protein Gaa1 PF04114.14 EMT53168.1 - 0.053 12.5 0.6 0.051 12.6 0.6 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component MARVEL PF01284.23 EMT53168.1 - 0.058 13.4 6.3 0.067 13.2 1.4 2.2 2 0 0 2 2 2 0 Membrane-associating domain DUF2306 PF10067.9 EMT53168.1 - 0.45 10.7 5.4 0.93 9.7 0.3 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) HTH_5 PF01022.20 EMT53169.1 - 5.1e-15 55.1 0.1 8.2e-15 54.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EMT53169.1 - 2.1e-14 53.3 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EMT53169.1 - 4.4e-07 29.7 0.0 5.9e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 EMT53169.1 - 8.2e-05 22.5 0.1 0.00014 21.8 0.1 1.4 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 EMT53169.1 - 0.00013 21.5 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 EMT53169.1 - 0.00013 21.7 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.12 EMT53169.1 - 0.00017 21.5 0.5 0.00029 20.7 0.2 1.6 2 0 0 2 2 2 1 HTH domain Sigma70_r4 PF04545.16 EMT53169.1 - 0.0012 18.3 0.0 0.0031 17.0 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_37 PF13744.6 EMT53169.1 - 0.0063 16.4 0.1 0.0083 16.1 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 EMT53169.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB UPF0122 PF04297.14 EMT53169.1 - 0.014 15.6 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_28 PF13518.6 EMT53169.1 - 0.026 14.6 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 EMT53169.1 - 0.027 14.8 0.0 0.035 14.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator EutK_C PF16365.5 EMT53169.1 - 0.038 14.0 0.1 0.072 13.1 0.1 1.6 1 1 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus Sigma70_r4_2 PF08281.12 EMT53169.1 - 0.043 13.5 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 EMT53169.1 - 0.06 13.2 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_40 PF14493.6 EMT53169.1 - 0.062 13.8 0.1 0.071 13.6 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 EMT53169.1 - 0.073 13.7 0.0 0.11 13.2 0.0 1.5 1 1 0 1 1 1 0 Homeodomain-like domain HTH_10 PF04967.12 EMT53169.1 - 0.084 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain DUF4423 PF14394.6 EMT53169.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF5316 PF17247.2 EMT53170.1 - 0.17 11.9 1.9 12 6.0 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5316) DUF4190 PF13828.6 EMT53170.1 - 1.1 9.0 6.3 1.5 8.6 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) Ribosomal_L5_C PF00673.21 EMT53171.1 - 0.036 14.2 0.0 0.095 12.9 0.0 1.7 1 0 0 1 1 1 0 ribosomal L5P family C-terminus Rrf2 PF02082.20 EMT53171.1 - 0.042 14.2 0.9 0.14 12.5 0.9 1.9 1 1 0 1 1 1 0 Transcriptional regulator MarR PF01047.22 EMT53171.1 - 0.051 13.5 1.0 0.89 9.5 0.3 2.9 2 1 0 2 2 2 0 MarR family HTH_53 PF18606.1 EMT53171.1 - 0.07 12.8 0.2 0.35 10.6 0.0 2.3 3 0 0 3 3 3 0 Zap helix turn helix N-terminal domain FeoC PF09012.10 EMT53171.1 - 0.16 12.1 0.3 0.46 10.6 0.2 1.8 1 1 0 1 1 1 0 FeoC like transcriptional regulator HXXEE PF13787.6 EMT53172.1 - 3e-22 79.5 6.8 3e-22 79.5 6.8 1.5 2 0 0 2 2 2 1 Protein of unknown function with HXXEE motif IncD PF17628.2 EMT53172.1 - 0.0063 16.3 2.6 0.0094 15.7 2.6 1.3 1 0 0 1 1 1 1 Inclusion membrane protein D GPI2 PF06432.11 EMT53172.1 - 0.022 14.2 9.8 0.028 13.9 9.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase tRNA-synt_1b PF00579.25 EMT53173.1 - 2.2e-79 266.9 0.0 2.6e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HTH_18 PF12833.7 EMT53175.1 - 1.6e-20 73.1 0.1 2.4e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EMT53175.1 - 1.1e-11 44.6 0.2 1.2e-05 25.2 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family LTD PF00932.19 EMT53176.1 - 3e-15 56.5 1.9 8.8e-15 55.0 0.7 2.6 2 0 0 2 2 2 1 Lamin Tail Domain Exo_endo_phos PF03372.23 EMT53176.1 - 2.6e-07 30.4 0.0 7.2e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family tRNA_anti-codon PF01336.25 EMT53176.1 - 9.7e-05 22.3 0.1 0.069 13.1 0.0 3.0 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain Exo_endo_phos_2 PF14529.6 EMT53176.1 - 0.00055 19.8 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Big_2 PF02368.18 EMT53176.1 - 2.9 7.8 9.2 0.42 10.5 0.7 3.5 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 2) Lyase_1 PF00206.20 EMT53177.1 - 3.5e-91 305.9 0.3 4.7e-91 305.4 0.3 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EMT53177.1 - 2.8e-17 62.9 0.1 1.7e-16 60.3 0.0 2.4 2 0 0 2 2 2 1 Fumarase C C-terminus ABM PF03992.16 EMT53178.1 - 1.3e-14 54.0 0.4 1.7e-14 53.7 0.4 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.6 EMT53178.1 - 0.0019 18.5 0.0 0.0022 18.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) DUF1330 PF07045.11 EMT53178.1 - 0.012 16.0 0.1 0.074 13.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) DUF5316 PF17247.2 EMT53179.1 - 0.00041 20.3 2.6 0.00049 20.0 0.2 2.2 2 1 0 2 2 2 1 Family of unknown function (DUF5316) DUF2721 PF11026.8 EMT53179.1 - 0.011 15.6 2.8 0.015 15.2 2.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) MscS_TM PF12794.7 EMT53179.1 - 0.022 13.6 0.3 0.024 13.5 0.3 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Xan_ur_permease PF00860.20 EMT53180.1 - 5.7e-35 120.8 42.4 5.7e-35 120.8 42.4 1.4 1 1 1 2 2 2 1 Permease family MFS_MOT1 PF16983.5 EMT53180.1 - 0.14 12.6 29.6 0.99 9.8 5.4 4.3 3 2 0 3 3 3 0 Molybdate transporter of MFS superfamily LysR_substrate PF03466.20 EMT53181.1 - 9.9e-40 136.1 0.2 1.4e-39 135.6 0.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT53181.1 - 2.7e-23 81.7 1.9 3.5e-23 81.3 0.3 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Lact-deh-memb PF09330.11 EMT53181.1 - 0.098 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding BCCT PF02028.17 EMT53182.1 - 6.5e-209 694.4 39.6 7.4e-209 694.2 39.6 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter ATG27 PF09451.10 EMT53182.1 - 0.36 10.6 0.7 0.68 9.7 0.7 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF523 PF04463.12 EMT53183.1 - 5.3e-44 149.6 0.0 6.4e-44 149.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF523) PRK PF00485.18 EMT53184.1 - 4.9e-13 49.3 0.0 7.5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EMT53184.1 - 0.024 15.2 0.0 0.063 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain HTH_IclR PF09339.10 EMT53184.1 - 0.03 14.1 0.2 2.1 8.2 0.1 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain CoaE PF01121.20 EMT53184.1 - 0.094 12.4 0.2 0.22 11.2 0.2 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase Ferritin PF00210.24 EMT53185.1 - 4.9e-35 120.5 0.7 5.7e-35 120.3 0.7 1.0 1 0 0 1 1 1 1 Ferritin-like domain TM1586_NiRdase PF14512.6 EMT53185.1 - 0.089 12.4 0.1 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 Putative TM nitroreductase Peptidase_S66 PF02016.15 EMT53186.1 - 3.8e-38 130.3 0.0 6.6e-38 129.5 0.0 1.4 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 EMT53186.1 - 4e-33 114.6 0.0 5.7e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain SBP_bac_5 PF00496.22 EMT53187.1 - 1.2e-79 268.0 8.4 2.1e-79 267.2 8.4 1.3 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle Sigma54_activat PF00158.26 EMT53188.1 - 5.5e-69 231.2 0.0 1.1e-68 230.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT53188.1 - 8.5e-22 77.8 0.0 6.1e-21 75.0 0.0 2.3 2 1 0 2 2 1 1 Sigma-54 interaction domain PAS_4 PF08448.10 EMT53188.1 - 1.3e-10 41.5 0.0 3.6e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold HTH_50 PF18024.1 EMT53188.1 - 1.1e-09 37.7 0.3 1.1e-09 37.7 0.3 1.9 2 0 0 2 2 1 1 Helix-turn-helix domain PAS PF00989.25 EMT53188.1 - 1.9e-08 34.3 0.0 4.8e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EMT53188.1 - 1.3e-06 28.6 0.1 1.3e-05 25.4 0.1 2.5 2 1 1 3 3 3 1 PAS domain AAA_5 PF07728.14 EMT53188.1 - 2.1e-06 27.8 0.0 5.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EMT53188.1 - 0.00031 21.2 0.0 0.00076 19.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT53188.1 - 0.00032 21.1 0.0 0.00054 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EMT53188.1 - 0.00034 20.1 0.1 0.068 12.5 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI HTH_8 PF02954.19 EMT53188.1 - 0.00046 19.9 0.1 0.001 18.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_1 PF00126.27 EMT53188.1 - 0.0028 17.6 0.2 0.0096 15.9 0.1 2.0 2 0 0 2 2 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MCM PF00493.23 EMT53188.1 - 0.0056 15.8 0.0 0.027 13.5 0.0 1.9 1 1 0 1 1 1 1 MCM P-loop domain AAA_2 PF07724.14 EMT53188.1 - 0.0066 16.6 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) HTH_23 PF13384.6 EMT53188.1 - 0.021 14.6 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain AAA_22 PF13401.6 EMT53188.1 - 0.021 15.1 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EMT53188.1 - 0.025 14.5 0.1 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 EMT53188.1 - 0.044 13.0 0.1 0.16 11.2 0.0 1.9 2 1 0 2 2 2 0 NB-ARC domain PAS_7 PF12860.7 EMT53188.1 - 0.055 13.6 0.0 0.36 11.0 0.0 2.2 1 1 0 1 1 1 0 PAS fold AAA_7 PF12775.7 EMT53188.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region HTH_22 PF13309.6 EMT53188.1 - 0.11 12.7 0.1 0.3 11.2 0.1 1.9 1 0 0 1 1 1 0 HTH domain Sigma70_r4 PF04545.16 EMT53188.1 - 0.11 12.0 0.3 0.31 10.6 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 PAS_10 PF13596.6 EMT53188.1 - 0.12 12.9 0.1 0.43 11.2 0.0 1.9 2 0 0 2 2 1 0 PAS domain PAS_3 PF08447.12 EMT53188.1 - 0.19 12.1 0.3 1.3 9.4 0.0 2.6 3 0 0 3 3 2 0 PAS fold HTH_10 PF04967.12 EMT53188.1 - 0.25 11.2 1.8 0.3 10.9 0.1 2.1 2 1 0 2 2 1 0 HTH DNA binding domain Response_reg PF00072.24 EMT53189.1 - 1e-26 93.3 0.5 1.7e-26 92.6 0.5 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HTH_11 PF08279.12 EMT53189.1 - 5.6e-07 29.4 0.1 1.9e-06 27.7 0.1 1.9 1 0 0 1 1 1 1 HTH domain FaeA PF04703.12 EMT53189.1 - 1.7e-06 28.3 0.5 2.2e-05 24.7 0.1 2.6 3 0 0 3 3 3 1 FaeA-like protein HTH_DeoR PF08220.12 EMT53189.1 - 3.6e-05 23.4 0.5 6.7e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_IclR PF09339.10 EMT53189.1 - 6.2e-05 22.7 0.1 0.00017 21.3 0.1 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 EMT53189.1 - 0.00028 20.4 0.2 0.00081 18.9 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EMT53189.1 - 0.00064 19.6 0.5 0.0024 17.7 0.1 2.2 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 EMT53189.1 - 0.0025 17.7 0.1 0.0079 16.2 0.1 1.9 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 EMT53189.1 - 0.0045 17.3 0.0 0.013 15.8 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulator HTH_17 PF12728.7 EMT53189.1 - 0.012 15.8 0.1 0.098 12.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain PadR PF03551.14 EMT53189.1 - 0.023 14.6 0.3 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 EMT53189.1 - 0.042 13.9 0.1 0.27 11.3 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HATPase_c PF02518.26 EMT53190.1 - 5.8e-17 62.2 0.1 1.2e-16 61.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase sCache_3_2 PF17203.4 EMT53190.1 - 1.7e-14 54.1 0.4 3.8e-14 53.0 0.4 1.6 1 0 0 1 1 1 1 Single cache domain 3 SPOB_a PF14689.6 EMT53190.1 - 2.5e-12 46.3 0.6 5.8e-12 45.1 0.6 1.6 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain HATPase_c_5 PF14501.6 EMT53190.1 - 1.1e-10 41.4 0.0 2.4e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 GHKL domain PAS_8 PF13188.7 EMT53190.1 - 6e-06 26.2 0.0 3.4e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EMT53190.1 - 4.1e-05 23.5 0.0 0.00014 21.8 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EMT53190.1 - 0.0002 21.6 0.1 0.0098 16.1 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_7 PF12860.7 EMT53190.1 - 0.00037 20.6 0.1 0.0026 17.9 0.0 2.4 1 1 1 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 EMT53190.1 - 0.00037 20.3 0.0 0.00069 19.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 EMT53190.1 - 0.0021 18.3 0.1 0.0078 16.5 0.1 2.1 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 EMT53190.1 - 0.0031 17.5 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_10 PF13596.6 EMT53190.1 - 0.02 15.5 0.9 0.18 12.4 0.1 2.8 3 1 0 3 3 2 0 PAS domain sCache_3_3 PF17202.4 EMT53190.1 - 0.025 15.0 0.0 0.59 10.6 0.0 2.4 2 0 0 2 2 2 0 Single cache domain 3 DctP PF03480.13 EMT53191.1 - 5.5e-98 327.8 1.3 6.9e-98 327.5 1.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 MEKHLA PF08670.11 EMT53191.1 - 0.0051 16.7 0.4 0.011 15.6 0.4 1.5 1 0 0 1 1 1 1 MEKHLA domain NMT1 PF09084.11 EMT53191.1 - 0.0073 16.3 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 NMT1/THI5 like PAS_9 PF13426.7 EMT53191.1 - 0.014 15.6 0.1 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 PAS domain ABC_membrane PF00664.23 EMT53192.1 - 4.4e-38 131.5 13.3 2.4e-37 129.1 12.2 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMT53192.1 - 3.5e-32 111.8 0.0 7e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT53192.1 - 3.2e-06 26.7 0.0 0.008 15.6 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMT53192.1 - 0.00025 21.0 0.0 0.00069 19.6 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EMT53192.1 - 0.00078 19.9 0.3 0.004 17.6 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT53192.1 - 0.0023 18.2 0.0 0.011 16.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EMT53192.1 - 0.0036 17.4 0.0 0.012 15.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EMT53192.1 - 0.027 14.2 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 EMT53192.1 - 0.055 13.5 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.6 EMT53192.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EMT53192.1 - 0.064 13.8 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EMT53192.1 - 0.16 11.8 0.2 1.3 8.7 0.1 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 EMT53193.1 - 8.8e-38 130.5 12.4 1.1e-37 130.2 12.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMT53193.1 - 2e-32 112.6 0.1 6.2e-32 111.0 0.1 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EMT53193.1 - 1.4e-05 24.7 0.2 0.0018 17.8 0.1 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 EMT53193.1 - 1.5e-05 24.8 0.2 0.028 14.1 0.1 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein NB-ARC PF00931.22 EMT53193.1 - 0.00058 19.1 0.0 0.0097 15.1 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 EMT53193.1 - 0.00067 19.9 0.4 0.0047 17.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EMT53193.1 - 0.0012 19.2 0.7 0.014 15.8 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 EMT53193.1 - 0.0031 17.6 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain MobB PF03205.14 EMT53193.1 - 0.0037 17.1 0.1 0.026 14.4 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 EMT53193.1 - 0.0056 16.6 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_7 PF12775.7 EMT53193.1 - 0.0084 15.6 0.9 0.016 14.8 0.0 1.8 2 0 0 2 2 1 1 P-loop containing dynein motor region AAA_29 PF13555.6 EMT53193.1 - 0.013 15.2 1.2 0.047 13.4 0.2 2.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 EMT53193.1 - 0.015 15.0 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 EMT53193.1 - 0.018 14.6 0.3 0.085 12.4 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EMT53193.1 - 0.022 15.2 0.2 0.27 11.7 0.2 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EMT53193.1 - 0.029 14.5 1.9 0.13 12.4 0.1 2.8 3 1 0 3 3 3 0 AAA domain TniB PF05621.11 EMT53193.1 - 0.031 13.7 0.2 0.22 10.9 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein MMR_HSR1 PF01926.23 EMT53193.1 - 0.033 14.3 0.1 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 EMT53193.1 - 0.033 14.1 0.1 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 EMT53193.1 - 0.04 14.0 0.0 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EMT53193.1 - 0.059 13.4 0.5 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 EMT53193.1 - 0.13 12.7 0.2 0.13 12.7 0.2 1.6 2 0 0 2 2 1 0 AAA domain Roc PF08477.13 EMT53193.1 - 0.15 12.3 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Guanylate_kin PF00625.21 EMT53193.1 - 0.17 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase Zeta_toxin PF06414.12 EMT53193.1 - 0.18 11.1 0.1 0.59 9.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Glycos_transf_4 PF00953.21 EMT53194.1 - 4.2e-39 134.1 16.0 1.1e-38 132.7 16.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 4 VIT1 PF01988.19 EMT53194.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.5 2 1 1 3 3 3 0 VIT family Halogen_Hydrol PF10112.9 EMT53194.1 - 6.7 6.7 6.1 2.5 8.1 0.4 2.9 2 1 1 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Multi_Drug_Res PF00893.19 EMT53195.1 - 6.6e-27 94.0 6.3 7.8e-27 93.8 6.3 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 EMT53195.1 - 0.0028 17.8 7.2 0.0038 17.4 7.2 1.2 1 0 0 1 1 1 1 EamA-like transporter family DUF308 PF03729.13 EMT53195.1 - 0.033 14.5 11.1 0.092 13.1 1.3 2.1 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DUF5360 PF17314.2 EMT53195.1 - 0.17 11.9 1.6 2.1 8.5 1.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) CPP1-like PF11833.8 EMT53195.1 - 0.89 9.2 3.3 1 9.0 3.3 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SCAMP PF04144.13 EMT53195.1 - 2 8.7 7.8 0.44 10.8 1.4 2.0 1 1 1 2 2 2 0 SCAMP family DUF4131 PF13567.6 EMT53195.1 - 5.6 6.6 9.4 1.5 8.4 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Multi_Drug_Res PF00893.19 EMT53196.1 - 1.1e-19 70.9 9.4 1.6e-19 70.3 9.4 1.2 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 EMT53196.1 - 0.0021 18.3 12.7 0.0032 17.6 12.7 1.3 1 1 0 1 1 1 1 EamA-like transporter family HCV_env PF01539.17 EMT53196.1 - 0.018 14.7 2.6 0.021 14.5 2.6 1.2 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 Peptidase_U4 PF03419.13 EMT53196.1 - 0.34 10.2 5.6 0.36 10.1 5.6 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DctM PF06808.12 EMT53197.1 - 1e-120 403.4 53.1 1.1e-120 403.2 53.1 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component CitMHS PF03600.16 EMT53197.1 - 6.5e-05 22.3 61.3 0.037 13.2 31.0 2.1 1 1 1 2 2 2 2 Citrate transporter DcuC PF03606.15 EMT53197.1 - 0.035 12.6 49.1 0.23 9.8 48.8 2.0 1 1 0 1 1 1 0 C4-dicarboxylate anaerobic carrier FAM176 PF14851.6 EMT53197.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 FAM176 family P5CR_dimer PF14748.6 EMT53197.1 - 7.8 6.8 9.1 1.2 9.4 3.7 2.4 3 0 0 3 3 3 0 Pyrroline-5-carboxylate reductase dimerisation Na_H_antiport_2 PF13726.6 EMT53197.1 - 9.2 6.5 14.4 0.12 12.5 3.9 3.2 3 0 0 3 3 3 0 Na+-H+ antiporter family DctQ PF04290.12 EMT53198.1 - 6.5e-32 110.2 3.1 7.7e-32 110.0 3.1 1.1 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component TMEM208_SND2 PF05620.11 EMT53198.1 - 0.2 11.5 3.0 0.24 11.2 0.6 2.0 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DctP PF03480.13 EMT53199.1 - 8.7e-102 340.3 2.1 1e-101 340.1 2.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 Na_sulph_symp PF00939.19 EMT53200.1 - 3e-57 194.7 41.9 3.8e-57 194.4 41.9 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EMT53200.1 - 1.5e-22 80.2 62.8 1e-20 74.2 38.5 2.1 1 1 1 2 2 2 2 Citrate transporter Peptidase_M61_N PF17899.1 EMT53201.1 - 0.017 15.2 0.1 0.022 14.8 0.1 1.1 1 0 0 1 1 1 0 Peptidase M61 N-terminal domain NAD_binding_7 PF13241.6 EMT53202.1 - 1.4e-29 102.6 0.0 2.2e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 EMT53202.1 - 5.2e-10 38.6 0.1 9.4e-10 37.8 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central TrkA_N PF02254.18 EMT53202.1 - 0.03 14.6 0.1 0.074 13.3 0.1 1.7 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 EMT53202.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TP_methylase PF00590.20 EMT53203.1 - 1.6e-50 172.0 1.4 2e-50 171.7 1.4 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DBI_PRT PF02277.17 EMT53204.1 - 3.1e-140 467.1 8.2 3.5e-140 466.9 8.2 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase GATase_3 PF07685.14 EMT53205.1 - 1.9e-52 177.8 0.0 2.7e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 EMT53205.1 - 1.2e-20 73.8 0.0 2.1e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 EMT53205.1 - 2.4e-19 70.0 0.0 1.4e-18 67.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain POC3_POC4 PF10448.9 EMT53205.1 - 0.23 11.5 0.0 0.39 10.7 0.0 1.3 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 GATase_3 PF07685.14 EMT53206.1 - 1.2e-38 132.7 0.0 1.7e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 EMT53206.1 - 2.9e-22 79.1 0.0 5.1e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 EMT53206.1 - 1.3e-14 54.5 1.9 5.1e-07 29.7 0.0 2.5 1 1 0 2 2 2 2 AAA domain DUF1611 PF07755.11 EMT53206.1 - 0.0078 15.5 2.1 0.041 13.2 2.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1611_C) P-loop domain AAA_19 PF13245.6 EMT53206.1 - 0.016 15.5 0.1 0.024 14.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain FTHFS PF01268.19 EMT53206.1 - 0.027 12.7 0.5 0.042 12.0 0.5 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Fer4_NifH PF00142.18 EMT53206.1 - 0.067 12.6 0.2 4.7 6.6 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NTPase_1 PF03266.15 EMT53206.1 - 0.23 11.4 2.7 0.18 11.7 0.8 1.7 2 0 0 2 2 2 0 NTPase CbiG_C PF01890.16 EMT53207.1 - 2.8e-36 124.6 0.0 4.8e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus CbiG_N PF11760.8 EMT53207.1 - 5.1e-35 119.3 0.1 1.2e-34 118.2 0.1 1.7 1 0 0 1 1 1 1 Cobalamin synthesis G N-terminal CbiG_mid PF11761.8 EMT53207.1 - 3.1e-13 49.6 0.1 6.7e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Cobalamin biosynthesis central region Glyco_tran_WecB PF03808.13 EMT53207.1 - 0.076 13.0 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Peptidase_M3_N PF08439.10 EMT53207.1 - 0.6 10.4 1.8 2.6 8.4 0.1 2.3 2 0 0 2 2 2 0 Oligopeptidase F TP_methylase PF00590.20 EMT53208.1 - 4.2e-51 173.9 3.4 4.9e-51 173.7 3.4 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.21 EMT53208.1 - 0.035 14.5 0.0 0.074 13.4 0.0 1.5 1 1 0 1 1 1 0 Radical SAM superfamily DUF2073 PF09846.9 EMT53208.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) TP_methylase PF00590.20 EMT53209.1 - 1.3e-50 172.3 0.0 1.5e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TP_methylase PF00590.20 EMT53210.1 - 7e-17 62.1 0.0 1.2e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Methyltransf_18 PF12847.7 EMT53210.1 - 1.1e-06 28.7 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT53210.1 - 0.00035 21.2 0.0 0.00077 20.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMT53210.1 - 0.00067 19.2 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EMT53210.1 - 0.026 15.2 0.0 0.058 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EMT53210.1 - 0.028 14.2 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 EMT53210.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CbiD PF01888.17 EMT53211.1 - 6.1e-95 317.3 4.4 7.4e-95 317.0 4.4 1.1 1 0 0 1 1 1 1 CbiD CbiC PF02570.15 EMT53212.1 - 2.5e-79 265.5 0.8 2.8e-79 265.3 0.8 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase Phage_Gp111 PF07410.11 EMT53212.1 - 0.058 13.9 0.2 0.16 12.5 0.2 1.7 2 0 0 2 2 2 0 Streptococcus thermophilus bacteriophage Gp111 protein CbiJ PF02571.14 EMT53213.1 - 1.5e-77 260.3 0.3 1.6e-77 260.1 0.3 1.0 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK MGS PF02142.22 EMT53213.1 - 0.0063 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain CbiX PF01903.17 EMT53214.1 - 1.1e-55 186.5 0.0 6e-28 97.3 0.1 2.2 2 0 0 2 2 2 2 CbiX Zip PF02535.22 EMT53214.1 - 8.9 5.4 32.2 12 5.0 32.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TP_methylase PF00590.20 EMT53215.1 - 6.3e-39 134.1 0.7 9.9e-39 133.5 0.7 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NIR_SIR PF01077.22 EMT53215.1 - 2e-10 40.4 0.0 4.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain GcpE PF04551.14 EMT53215.1 - 0.0042 16.2 0.0 0.007 15.5 0.0 1.4 1 0 0 1 1 1 1 GcpE protein CobD_Cbib PF03186.13 EMT53216.1 - 6.5e-102 340.5 3.1 7.7e-102 340.2 3.1 1.0 1 0 0 1 1 1 1 CobD/Cbib protein His_Phos_1 PF00300.22 EMT53217.1 - 1.8e-47 161.6 0.9 2e-47 161.4 0.9 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CobS PF02654.15 EMT53218.1 - 1.8e-55 188.4 15.4 2.1e-55 188.1 15.4 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase CobU PF02283.16 EMT53219.1 - 8.9e-55 184.8 0.1 1e-54 184.7 0.1 1.0 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_18 PF13238.6 EMT53219.1 - 0.0011 19.5 0.0 0.0017 18.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EMT53219.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 EMT53219.1 - 0.013 15.8 0.0 0.015 15.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Aminotran_1_2 PF00155.21 EMT53220.1 - 1.2e-37 130.0 0.0 1.4e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Nucleoside_tran PF01733.18 EMT53220.1 - 0.27 10.6 0.0 0.43 9.9 0.0 1.3 1 0 0 1 1 1 0 Nucleoside transporter CobA_CobO_BtuR PF02572.15 EMT53221.1 - 2e-61 207.2 0.0 2.4e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA PF00004.29 EMT53221.1 - 0.0013 19.2 0.0 0.0049 17.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 EMT53221.1 - 0.0017 18.4 0.9 0.0037 17.3 0.9 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 EMT53221.1 - 0.0041 16.7 0.6 0.69 9.5 0.0 2.3 2 1 0 2 2 2 2 AAA domain AAA_31 PF13614.6 EMT53221.1 - 0.0083 16.1 0.6 0.046 13.6 0.1 2.0 1 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EMT53221.1 - 0.0097 15.6 0.0 0.038 13.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EMT53221.1 - 0.053 13.5 0.8 1.7 8.6 0.6 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit KdpD PF02702.17 EMT53221.1 - 0.063 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Peptidase_M15 PF01427.17 EMT53222.1 - 1.8e-24 86.6 0.1 2.6e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 D-ala-D-ala dipeptidase VanY PF02557.17 EMT53222.1 - 0.00046 20.0 1.1 0.0028 17.5 1.1 2.0 1 1 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase SBP_bac_5 PF00496.22 EMT53223.1 - 2.7e-91 306.4 4.8 3.6e-91 306.0 4.8 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle SBP_bac_3 PF00497.20 EMT53223.1 - 0.054 12.9 0.2 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 BPD_transp_1 PF00528.22 EMT53224.1 - 7e-36 123.7 12.1 7e-36 123.7 12.1 2.1 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EMT53225.1 - 1.1e-29 103.5 9.8 1.1e-29 103.5 9.8 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT53225.1 - 7.3e-08 32.3 0.9 7.3e-08 32.3 0.9 2.8 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C SLC3A2_N PF16028.5 EMT53225.1 - 0.01 15.4 0.2 0.036 13.6 0.2 1.9 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus ABC_tran PF00005.27 EMT53226.1 - 5.3e-28 98.2 0.0 7.2e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT53226.1 - 1.6e-20 73.3 0.1 3.2e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT53226.1 - 1.8e-08 34.6 2.3 3.2e-07 30.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT53226.1 - 4.7e-05 22.9 0.1 7.7e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT53226.1 - 0.00028 21.2 0.4 0.0042 17.4 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMT53226.1 - 0.0098 15.6 1.0 3.4 7.3 0.0 2.3 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 EMT53226.1 - 0.013 15.2 0.2 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.9 EMT53226.1 - 0.025 13.8 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 EMT53226.1 - 0.048 13.4 0.1 0.097 12.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT53226.1 - 0.1 13.0 0.2 0.16 12.3 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 EMT53226.1 - 0.14 11.8 0.3 0.67 9.6 0.1 2.2 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 EMT53226.1 - 0.16 11.5 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EMT53227.1 - 2.2e-30 105.9 0.0 3.1e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT53227.1 - 6.5e-10 39.3 3.2 8.2e-08 32.4 0.2 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 EMT53227.1 - 2e-06 28.2 0.1 3.7e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EMT53227.1 - 3e-05 23.6 0.1 0.00023 20.7 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMT53227.1 - 0.0055 16.4 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 EMT53227.1 - 0.02 13.6 1.7 0.066 11.8 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.6 EMT53227.1 - 0.035 14.4 1.8 0.56 10.5 1.8 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMT53227.1 - 0.045 13.3 0.0 0.23 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMT53227.1 - 0.26 11.7 1.6 1.2 9.5 1.6 2.0 1 1 0 1 1 1 0 AAA ATPase domain Cupin_2 PF07883.11 EMT53228.1 - 2.8e-15 55.8 0.0 4.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain HTH_3 PF01381.22 EMT53228.1 - 1.3e-12 47.5 0.0 2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EMT53228.1 - 1.1e-10 41.3 0.0 2.8e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 EMT53228.1 - 5.5e-09 36.2 0.0 9.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EMT53228.1 - 1.2e-06 28.9 0.0 9.2e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EMT53228.1 - 5.6e-06 26.1 0.3 1.6e-05 24.7 0.3 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain MannoseP_isomer PF01050.18 EMT53228.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.5 1 1 0 1 1 1 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 EMT53228.1 - 0.0029 17.5 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_37 PF13744.6 EMT53228.1 - 0.042 13.8 0.1 0.08 12.9 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.16 EMT53229.1 - 2e-51 175.0 61.9 8.8e-51 172.9 58.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT53229.1 - 6.9e-20 71.3 40.6 1.9e-15 56.7 12.2 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EMT53229.1 - 6.7e-07 28.1 27.8 9.3e-07 27.6 27.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EMT53229.1 - 0.00051 18.7 46.9 0.007 15.0 8.9 3.8 2 1 2 4 4 4 2 MFS/sugar transport protein 7TMR-DISM_7TM PF07695.11 EMT53229.1 - 0.013 15.4 10.4 0.013 15.4 10.4 4.2 3 1 0 4 4 4 0 7TM diverse intracellular signalling SLATT_1 PF18181.1 EMT53229.1 - 3.9 7.4 7.3 0.24 11.3 1.4 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 OATP PF03137.20 EMT53229.1 - 4.3 5.5 23.3 0.12 10.6 5.8 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Spc7_N PF15402.6 EMT53230.1 - 0.0043 15.4 8.3 0.0045 15.3 8.3 1.1 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Presenilin PF01080.17 EMT53230.1 - 0.05 12.4 4.4 0.059 12.1 4.4 1.1 1 0 0 1 1 1 0 Presenilin TP53IP5 PF15331.6 EMT53230.1 - 0.29 11.3 6.0 0.38 10.9 6.0 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DAG_kinase_N PF14513.6 EMT53230.1 - 0.4 10.9 4.5 0.53 10.5 4.5 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Ndc1_Nup PF09531.10 EMT53230.1 - 1.1 7.9 10.2 1.2 7.7 10.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pyr_redox_2 PF07992.14 EMT53231.1 - 4.9e-14 52.3 5.2 2.3e-11 43.5 1.4 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMT53231.1 - 3e-09 36.5 10.1 6.2e-06 25.6 0.6 3.0 1 1 2 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.6 EMT53231.1 - 5.3e-09 35.8 1.5 0.00056 19.3 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT53231.1 - 8.7e-09 34.6 0.7 3.6e-06 26.0 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 EMT53231.1 - 2.3e-08 34.0 0.6 0.00015 21.5 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EMT53231.1 - 1.1e-07 31.6 4.2 2.6e-06 27.0 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMT53231.1 - 5e-07 29.8 0.2 0.00046 20.2 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EMT53231.1 - 1.4e-06 27.8 0.4 2.2e-05 23.9 0.0 2.0 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 EMT53231.1 - 2.1e-06 27.1 6.7 2.8e-05 23.4 0.2 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EMT53231.1 - 9.7e-05 22.5 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMT53231.1 - 0.0033 16.5 1.3 0.061 12.4 0.2 2.0 1 1 1 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.18 EMT53231.1 - 0.008 16.1 0.3 0.011 15.6 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 EMT53231.1 - 0.017 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 EMT53231.1 - 0.022 13.9 0.1 4.8 6.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) F420_oxidored PF03807.17 EMT53231.1 - 0.12 12.9 3.0 0.11 13.1 0.4 2.4 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 EMT53231.1 - 0.2 10.9 5.3 0.38 10.0 3.2 2.3 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TetR_N PF00440.23 EMT53232.1 - 2.7e-17 62.3 1.5 4.6e-17 61.5 1.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EMT53232.1 - 0.00023 21.4 0.0 0.00049 20.3 0.0 1.7 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_4 PF08359.11 EMT53232.1 - 0.0028 17.8 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 YsiA-like protein, C-terminal region TetR_C_26 PF17934.1 EMT53232.1 - 0.0044 17.3 0.1 0.011 16.0 0.0 1.8 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 EMT53232.1 - 0.0081 16.9 1.2 0.019 15.7 0.1 2.2 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Glyco_hydro_cc PF11790.8 EMT53232.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core COX4_pro PF03626.14 EMT53233.1 - 9.4e-15 54.8 13.5 1.2e-14 54.4 13.5 1.1 1 0 0 1 1 1 1 Prokaryotic Cytochrome C oxidase subunit IV Polysacc_synt PF01943.17 EMT53233.1 - 8.8e-05 22.0 8.1 0.0001 21.8 8.1 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ATG22 PF11700.8 EMT53233.1 - 0.0018 17.0 2.3 0.002 16.8 2.3 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like YwiC PF14256.6 EMT53233.1 - 0.014 15.7 1.9 0.018 15.4 1.9 1.3 1 0 0 1 1 1 0 YwiC-like protein EcsB PF05975.12 EMT53233.1 - 0.039 12.8 9.2 0.049 12.5 9.2 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB CRPA PF05745.11 EMT53233.1 - 0.096 12.7 4.6 0.14 12.2 4.6 1.2 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF1761 PF08570.10 EMT53233.1 - 0.17 12.2 7.7 1.6 9.0 7.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1761) Otopetrin PF03189.13 EMT53233.1 - 1.2 7.9 8.4 1.4 7.7 8.4 1.3 1 1 0 1 1 1 0 Otopetrin DUF4870 PF09685.10 EMT53233.1 - 1.5 8.9 14.0 0.095 12.8 7.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4870) DUF3290 PF11694.8 EMT53233.1 - 5.2 7.0 8.8 2.6 8.0 4.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3290) EVC2_like PF12297.8 EMT53233.1 - 6.2 5.4 8.2 2.5 6.7 1.1 2.0 1 1 1 2 2 2 0 Ellis van Creveld protein 2 like protein COX3 PF00510.18 EMT53234.1 - 1.8e-17 64.0 19.4 6e-17 62.3 19.4 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III ESSS PF10183.9 EMT53234.1 - 0.04 14.1 0.4 0.04 14.1 0.4 1.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CbtA PF09490.10 EMT53234.1 - 0.61 9.8 10.5 0.2 11.4 3.2 2.6 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtA) COX1 PF00115.20 EMT53235.1 - 4.6e-146 487.1 67.9 4.6e-146 487.1 67.9 2.2 2 0 0 2 2 2 2 Cytochrome C and Quinol oxidase polypeptide I E1-E2_ATPase PF00122.20 EMT53235.1 - 8.8 5.8 8.1 17 4.9 6.5 2.3 1 1 0 1 1 1 0 E1-E2 ATPase COX2 PF00116.20 EMT53236.1 - 1.1e-06 28.6 0.0 1.1e-05 25.3 0.0 2.1 1 1 1 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 EMT53236.1 - 1e-05 25.6 1.6 2.2e-05 24.5 1.6 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain COX_ARM PF06481.14 EMT53236.1 - 6e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 COX Aromatic Rich Motif Sulf_transp PF04143.14 EMT53236.1 - 0.039 13.5 3.1 0.16 11.5 2.5 1.9 1 1 1 2 2 2 0 Sulphur transport 7TM_GPCR_Str PF10326.9 EMT53236.1 - 0.048 13.0 0.9 0.067 12.5 0.9 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str CopD PF05425.13 EMT53236.1 - 0.059 13.8 0.1 0.098 13.1 0.1 1.3 1 0 0 1 1 1 0 Copper resistance protein D Orf78 PF06024.12 EMT53236.1 - 0.15 12.4 1.0 0.49 10.7 0.2 2.2 2 0 0 2 2 2 0 Orf78 (ac78) DUF4131 PF13567.6 EMT53236.1 - 0.24 11.1 1.0 0.27 10.9 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) E1-E2_ATPase PF00122.20 EMT53237.1 - 0.028 13.9 1.9 0.033 13.7 1.9 1.0 1 0 0 1 1 1 0 E1-E2 ATPase DUF2304 PF10066.9 EMT53237.1 - 0.1 12.8 4.7 0.11 12.7 4.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DUF2892 PF11127.8 EMT53237.1 - 0.2 11.7 2.7 0.58 10.2 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Ala_racemase_N PF01168.20 EMT53238.1 - 1.9e-58 197.7 0.0 2.7e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 EMT53238.1 - 7e-45 151.8 0.2 1.2e-44 151.0 0.2 1.4 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain Acyl_transf_3 PF01757.22 EMT53239.1 - 6.7e-22 78.0 32.8 7.8e-22 77.8 32.8 1.0 1 0 0 1 1 1 1 Acyltransferase family DUF2070 PF09843.9 EMT53239.1 - 7.6 4.7 19.0 0.036 12.4 9.4 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) VanY PF02557.17 EMT53240.1 - 4.9e-30 104.1 0.0 6.7e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Dala_Dala_lig_C PF07478.13 EMT53241.1 - 9.9e-65 217.9 0.0 1.3e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 EMT53241.1 - 8.1e-30 103.3 0.0 3.3e-29 101.4 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 EMT53241.1 - 2.3e-11 43.6 0.1 4.1e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EMT53241.1 - 5.3e-08 32.6 0.2 1.5e-07 31.2 0.2 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 EMT53241.1 - 2.6e-05 23.9 0.1 0.00019 21.0 0.1 2.2 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EMT53241.1 - 4.6e-05 23.5 0.0 0.00013 22.1 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EMT53241.1 - 0.00051 19.4 0.0 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 EMT53241.1 - 0.022 14.5 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MerR_1 PF13411.6 EMT53242.1 - 4.8e-19 68.2 0.0 8.4e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 EMT53242.1 - 2.5e-17 62.3 0.2 4.5e-17 61.5 0.2 1.4 1 0 0 1 1 1 1 MerR family regulatory protein AbiEi_4 PF13338.6 EMT53242.1 - 1.1e-05 25.5 0.0 4e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin MerR-DNA-bind PF09278.11 EMT53242.1 - 0.00011 22.6 0.3 0.0005 20.6 0.3 1.9 1 1 0 1 1 1 1 MerR, DNA binding CDH1_2_SANT_HL1 PF18375.1 EMT53242.1 - 0.0055 17.3 0.4 0.0072 17.0 0.4 1.2 1 0 0 1 1 1 1 CDH1/2 SANT-Helical linker 1 Phytochelatin PF05023.14 EMT53242.1 - 0.007 15.6 0.0 0.0072 15.6 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase HTH_17 PF12728.7 EMT53242.1 - 0.0076 16.4 0.0 0.028 14.6 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain PI3K_P85_iSH2 PF16454.5 EMT53242.1 - 0.008 15.8 0.4 0.011 15.4 0.4 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Prefoldin_2 PF01920.20 EMT53242.1 - 0.013 15.4 2.1 0.021 14.8 2.1 1.3 1 1 0 1 1 1 0 Prefoldin subunit DASH_Spc19 PF08287.11 EMT53242.1 - 0.014 15.3 0.5 0.025 14.5 0.5 1.3 1 0 0 1 1 1 0 Spc19 HTH_23 PF13384.6 EMT53242.1 - 0.032 14.0 0.0 0.72 9.7 0.0 2.5 3 0 0 3 3 3 0 Homeodomain-like domain DUF4795 PF16043.5 EMT53242.1 - 0.033 13.8 0.4 0.041 13.5 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DASH_Duo1 PF08651.10 EMT53242.1 - 0.042 13.6 0.1 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 TMCCDC2 PF15844.5 EMT53242.1 - 0.19 11.6 0.3 0.23 11.4 0.3 1.2 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 EamA PF00892.20 EMT53243.1 - 6.3e-50 168.9 40.3 2.2e-25 89.4 17.8 2.0 2 0 0 2 2 2 2 EamA-like transporter family Trans_reg_C PF00486.28 EMT53244.1 - 2.1e-27 95.0 0.0 3.5e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 EMT53244.1 - 7.1e-27 93.8 0.0 9.6e-27 93.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HTH_11 PF08279.12 EMT53244.1 - 0.024 14.6 0.0 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 HTH domain GerE PF00196.19 EMT53244.1 - 0.15 11.6 0.6 0.71 9.5 0.2 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family CCB1 PF12046.8 EMT53244.1 - 0.17 11.2 0.0 0.77 9.1 0.0 1.9 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B PALP PF00291.25 EMT53245.1 - 5.7e-84 282.0 0.3 6.5e-84 281.8 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GARS_N PF02844.15 EMT53245.1 - 0.032 15.0 0.1 1.4 9.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain HTH_22 PF13309.6 EMT53245.1 - 0.14 12.3 1.3 4.3 7.5 0.0 3.2 4 0 0 4 4 4 0 HTH domain YjgF_endoribonc PF14588.6 EMT53246.1 - 1.4e-22 80.4 0.0 1.6e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 EMT53246.1 - 2.2e-13 50.3 0.0 2.8e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP MOEP19 PF16005.5 EMT53246.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.6 2 0 0 2 2 2 0 KH-like RNA-binding domain MFS_1 PF07690.16 EMT53247.1 - 4.7e-63 213.3 47.7 5.3e-46 157.2 25.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT53247.1 - 2.7e-18 66.0 31.7 9.7e-10 37.8 12.9 2.1 1 1 1 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 EMT53247.1 - 1.9e-16 59.7 32.7 3.1e-10 39.2 14.7 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 EMT53247.1 - 7.6e-15 54.7 26.7 2.8e-14 52.9 11.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 EMT53247.1 - 5e-13 48.3 12.8 5e-13 48.3 12.8 1.8 1 1 0 2 2 2 1 Transmembrane secretion effector MFS_4 PF06779.14 EMT53247.1 - 7.9e-09 35.3 24.8 1.1e-08 34.8 24.8 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB UNC-93 PF05978.16 EMT53247.1 - 0.00026 20.8 5.7 0.00026 20.8 5.7 2.8 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 OATP PF03137.20 EMT53247.1 - 0.014 13.7 32.4 0.08 11.2 2.5 4.1 1 1 3 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family CobD_Cbib PF03186.13 EMT53247.1 - 0.035 13.3 2.5 3.3 6.9 0.1 2.6 2 1 0 2 2 2 0 CobD/Cbib protein IclR PF01614.18 EMT53248.1 - 2e-29 102.0 0.0 2.9e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EMT53248.1 - 1.1e-10 41.1 0.0 2.5e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.6 EMT53248.1 - 8.1e-05 22.3 0.1 0.00058 19.6 0.0 2.4 3 0 0 3 3 2 1 Homeodomain-like domain HTH_11 PF08279.12 EMT53248.1 - 0.00041 20.2 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 EMT53248.1 - 0.0029 17.5 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 EMT53248.1 - 0.0062 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EMT53248.1 - 0.0067 16.3 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_Mga PF08280.11 EMT53248.1 - 0.009 16.0 0.0 0.058 13.4 0.0 2.3 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain GntR PF00392.21 EMT53248.1 - 0.011 15.4 0.1 0.24 11.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 EMT53248.1 - 0.012 15.9 0.0 0.085 13.2 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator HTH_6 PF01418.17 EMT53248.1 - 0.031 14.3 0.1 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_32 PF13565.6 EMT53248.1 - 0.031 14.9 0.2 0.18 12.4 0.0 2.3 3 0 0 3 3 3 0 Homeodomain-like domain HTH_29 PF13551.6 EMT53248.1 - 0.035 14.1 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_38 PF13936.6 EMT53248.1 - 0.083 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 EMT53248.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain SpoIIID PF12116.8 EMT53248.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D Neugrin PF06413.11 EMT53248.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Neugrin Asp_Glu_race PF01177.22 EMT53249.1 - 1.3e-09 38.2 0.0 0.0002 21.3 0.0 2.0 2 0 0 2 2 2 2 Asp/Glu/Hydantoin racemase Pantoate_transf PF02548.15 EMT53249.1 - 0.0064 15.9 0.8 0.014 14.8 0.3 1.7 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase Peptidase_M29 PF02073.15 EMT53250.1 - 2.8e-11 42.8 0.9 5.8e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 Thermophilic metalloprotease (M29) AroM PF07302.11 EMT53251.1 - 5.3e-71 238.5 0.4 5.9e-71 238.3 0.4 1.0 1 0 0 1 1 1 1 AroM protein Asp_Glu_race PF01177.22 EMT53251.1 - 0.0021 18.0 0.3 0.58 10.0 0.0 2.1 1 1 0 2 2 2 2 Asp/Glu/Hydantoin racemase Ligase_CoA PF00549.19 EMT53251.1 - 0.059 13.2 0.2 1.3 8.8 0.0 2.5 3 0 0 3 3 3 0 CoA-ligase His_Phos_1 PF00300.22 EMT53251.1 - 0.099 12.3 0.0 0.5 10.0 0.0 1.8 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) DUF1177 PF06675.11 EMT53252.1 - 6.4e-136 451.5 0.1 7.6e-136 451.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1177) DUF917 PF06032.12 EMT53253.1 - 2.8e-60 204.0 1.6 3.4e-60 203.7 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF917) OPT PF03169.15 EMT53254.1 - 3.5e-33 115.1 42.9 1.1e-20 73.9 27.6 2.2 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DUF2070 PF09843.9 EMT53254.1 - 0.25 9.6 21.1 0.0042 15.4 6.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Cupredoxin_1 PF13473.6 EMT53255.1 - 8.3e-09 35.5 0.3 1.2e-08 35.0 0.3 1.4 1 1 0 1 1 1 1 Cupredoxin-like domain COX2 PF00116.20 EMT53255.1 - 0.00015 21.7 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Copper-bind PF00127.20 EMT53255.1 - 0.0015 19.0 1.3 0.1 13.0 0.1 2.3 1 1 1 2 2 2 1 Copper binding proteins, plastocyanin/azurin family LPAM_2 PF13627.6 EMT53255.1 - 0.032 14.1 3.5 0.059 13.2 3.5 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site CarbopepD_reg_2 PF13715.6 EMT53255.1 - 0.14 12.2 0.6 6.7 6.8 0.1 2.2 1 1 1 2 2 2 0 CarboxypepD_reg-like domain DUF2850 PF11012.8 EMT53255.1 - 0.19 12.0 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) DUF3558 PF12079.8 EMT53255.1 - 7.4 6.5 9.3 11 5.9 6.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3558) MttA_Hcf106 PF02416.16 EMT53256.1 - 7.9e-21 73.1 0.1 9.2e-21 72.9 0.1 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family TatC PF00902.18 EMT53257.1 - 4.2e-50 170.5 17.5 4.8e-50 170.3 17.5 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) GMC_oxred_C PF05199.13 EMT53258.1 - 3.9e-20 72.8 0.0 7.7e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMT53258.1 - 1.3e-10 41.2 0.0 1.8e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 EMT53258.1 - 0.00068 19.3 0.0 0.0026 17.4 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMT53258.1 - 0.0007 18.9 0.7 0.066 12.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMT53258.1 - 0.0016 17.6 0.7 1.9 7.4 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain FAD_binding_3 PF01494.19 EMT53258.1 - 0.0018 17.6 1.3 0.0086 15.4 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EMT53258.1 - 0.042 12.9 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 EMT53258.1 - 0.054 12.8 0.5 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMT53258.1 - 0.14 12.4 0.6 0.71 10.1 0.2 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 EMT53258.1 - 0.33 10.6 3.1 0.18 11.4 0.4 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Gluconate_2-dh3 PF13618.6 EMT53259.1 - 2e-35 122.0 0.1 2.8e-35 121.5 0.1 1.2 1 0 0 1 1 1 1 Gluconate 2-dehydrogenase subunit 3 MarR PF01047.22 EMT53260.1 - 1.7e-13 50.3 0.0 3.2e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EMT53260.1 - 3.4e-10 40.3 0.0 6.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 EMT53260.1 - 1.4e-09 37.7 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 EMT53260.1 - 7.8e-07 28.9 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EMT53260.1 - 1.4e-05 24.6 0.0 2.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 EMT53260.1 - 2.8e-05 24.2 0.0 9.6e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 EMT53260.1 - 9.5e-05 22.3 0.1 0.00022 21.1 0.0 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 EMT53260.1 - 0.001 18.7 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 EMT53260.1 - 0.0038 16.9 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_5 PF01022.20 EMT53260.1 - 0.0045 16.8 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_34 PF13601.6 EMT53260.1 - 0.011 15.9 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_36 PF13730.6 EMT53260.1 - 0.013 15.5 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 EMT53260.1 - 0.026 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_IclR PF09339.10 EMT53260.1 - 0.029 14.2 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain Rrf2 PF02082.20 EMT53260.1 - 0.046 14.1 0.1 0.77 10.1 0.0 2.5 1 1 1 3 3 3 0 Transcriptional regulator Replic_Relax PF13814.6 EMT53260.1 - 0.047 13.7 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation PadR PF03551.14 EMT53260.1 - 0.11 12.5 0.2 0.38 10.7 0.0 2.0 2 1 0 2 2 2 0 Transcriptional regulator PadR-like family PMT2_N PF17987.1 EMT53260.1 - 0.11 12.7 0.7 0.24 11.6 0.4 1.7 2 0 0 2 2 2 0 Phosphoethanolamine N-methyltransferase 2 N-terminal Peptidase_M56 PF05569.11 EMT53261.1 - 1.9e-59 201.3 3.5 1.3e-58 198.6 3.5 1.9 1 1 0 1 1 1 1 BlaR1 peptidase M56 Peptidase_M48 PF01435.18 EMT53261.1 - 0.00058 19.7 0.0 0.00099 18.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF1935 PF09149.10 EMT53261.1 - 0.15 12.5 0.3 0.42 11.0 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) DUF4173 PF13777.6 EMT53261.1 - 0.58 9.6 3.1 3.4 7.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4173) Penicillinase_R PF03965.16 EMT53262.1 - 5.1e-37 126.8 0.3 5.7e-37 126.6 0.3 1.0 1 0 0 1 1 1 1 Penicillinase repressor ANAPC2 PF08672.11 EMT53262.1 - 0.00088 19.7 0.1 0.089 13.3 0.0 2.4 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 DUF3489 PF11994.8 EMT53262.1 - 0.001 19.1 0.2 0.0022 18.0 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF3489) TFIIE_alpha PF02002.17 EMT53262.1 - 0.0013 18.6 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 1 TFIIE alpha subunit HTH_DeoR PF08220.12 EMT53262.1 - 0.0081 15.9 0.0 0.088 12.6 0.0 2.2 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain TrmB PF01978.19 EMT53262.1 - 0.017 15.0 0.1 0.053 13.4 0.0 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB SMC_ScpB PF04079.16 EMT53262.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.5 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB HTH_20 PF12840.7 EMT53262.1 - 0.024 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PaaX PF07848.12 EMT53262.1 - 0.032 14.4 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein MarR PF01047.22 EMT53262.1 - 0.033 14.1 0.1 0.087 12.8 0.1 1.8 1 1 0 1 1 1 0 MarR family HTH_24 PF13412.6 EMT53262.1 - 0.056 13.0 0.0 0.86 9.2 0.0 2.3 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding NuiA PF07924.11 EMT53262.1 - 0.072 13.5 0.3 0.13 12.6 0.1 1.7 1 1 0 1 1 1 0 Nuclease A inhibitor-like protein Dimerisation PF08100.11 EMT53262.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain ERp29 PF07749.12 EMT53262.1 - 0.18 12.7 2.1 0.66 10.9 2.1 2.0 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain SpoVR PF04293.13 EMT53263.1 - 4.9e-170 565.7 0.0 5.8e-170 565.5 0.0 1.0 1 0 0 1 1 1 1 SpoVR like protein DUF2975 PF11188.8 EMT53264.1 - 0.047 13.6 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) APH PF01636.23 EMT53265.1 - 2.4e-29 103.0 0.1 2.8e-29 102.7 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EMT53265.1 - 0.00012 21.1 0.0 0.00019 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EMT53265.1 - 0.0062 16.1 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EMT53265.1 - 0.0083 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 EMT53265.1 - 0.049 12.8 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Fructosamine kinase DUF423 PF04241.15 EMT53267.1 - 5.9e-31 106.5 5.7 5.9e-31 106.5 5.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF423) DoxX PF07681.12 EMT53269.1 - 5.8e-21 74.9 7.5 8e-21 74.4 7.5 1.2 1 0 0 1 1 1 1 DoxX DoxX_2 PF13564.6 EMT53269.1 - 5e-09 36.2 6.0 5.9e-09 36.0 6.0 1.2 1 0 0 1 1 1 1 DoxX-like family MauE PF07291.11 EMT53269.1 - 0.018 14.8 0.6 0.024 14.4 0.6 1.1 1 0 0 1 1 1 0 Methylamine utilisation protein MauE DoxD PF04173.13 EMT53269.1 - 0.092 12.6 6.2 0.38 10.6 3.9 2.0 1 1 1 2 2 2 0 TQO small subunit DoxD MFS_1 PF07690.16 EMT53270.1 - 1.5e-47 162.3 58.2 1.5e-36 126.1 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT53270.1 - 6.5e-08 31.8 22.3 1.4e-06 27.4 22.3 2.2 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 EMT53270.1 - 2.6e-07 29.4 22.0 1.3e-06 27.1 21.7 1.9 1 1 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.24 EMT53270.1 - 3.9e-07 29.3 26.0 7.9e-06 25.0 12.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.19 EMT53270.1 - 9.4e-05 21.3 18.2 0.00013 20.9 18.2 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter HTH_5 PF01022.20 EMT53271.1 - 2.4e-10 40.1 0.5 4.1e-10 39.3 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EMT53271.1 - 4.2e-09 36.3 2.2 3.6e-08 33.4 3.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 EMT53271.1 - 1.6e-06 27.5 0.1 2.9e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 EMT53271.1 - 1.7e-06 27.8 3.2 3.9e-06 26.6 3.2 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EMT53271.1 - 0.00093 19.0 1.4 0.0031 17.4 0.9 2.0 2 0 0 2 2 2 1 MarR family RP-C PF03428.13 EMT53271.1 - 0.0027 17.4 0.1 0.0071 16.0 0.0 1.6 2 0 0 2 2 2 1 Replication protein C N-terminal domain MarR PF01047.22 EMT53271.1 - 0.0035 17.2 0.3 0.0084 16.0 0.3 1.6 1 0 0 1 1 1 1 MarR family LexA_DNA_bind PF01726.16 EMT53271.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain Rrf2 PF02082.20 EMT53271.1 - 0.031 14.6 0.2 0.064 13.6 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator Sulfolobus_pRN PF05584.11 EMT53271.1 - 0.048 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein HTH_40 PF14493.6 EMT53271.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain OEP PF02321.18 EMT53272.1 - 2.2e-08 34.1 15.0 2.2e-08 34.1 15.0 5.2 4 2 1 5 5 5 3 Outer membrane efflux protein Tup_N PF08581.10 EMT53272.1 - 0.56 10.5 7.8 0.2 12.0 0.5 3.5 3 0 0 3 3 3 0 Tup N-terminal YdjM PF04307.14 EMT53273.1 - 1.1e-26 93.2 12.9 1.7e-26 92.6 12.9 1.3 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase DUF350 PF03994.14 EMT53274.1 - 1.9e-34 117.6 8.5 1.9e-19 69.6 0.2 2.1 2 0 0 2 2 2 2 Domain of Unknown Function (DUF350) DUF202 PF02656.15 EMT53274.1 - 0.046 14.2 1.7 0.43 11.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF202) GSP_synth PF03738.14 EMT53275.1 - 1.6e-71 241.5 0.0 1.9e-71 241.3 0.0 1.0 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CP_ATPgrasp_2 PF14403.6 EMT53275.1 - 8e-05 21.7 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 PRK PF00485.18 EMT53277.1 - 0.022 14.5 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF1258 PF06869.12 EMT53277.1 - 0.2 11.1 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Peptidase_M3 PF01432.20 EMT53278.1 - 7.3e-20 71.7 7.1 4.1e-19 69.2 7.1 1.9 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 EMT53278.1 - 1.6e-11 44.3 0.0 6.2e-11 42.4 0.0 2.2 1 0 0 1 1 1 1 Oligopeptidase F Peptidase_M32 PF02074.15 EMT53278.1 - 0.0017 17.3 0.1 0.003 16.4 0.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase DUF2313 PF10076.9 EMT53278.1 - 0.091 12.6 0.1 5.9 6.7 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein conserved in bacteria (DUF2313) Sipho_Gp157 PF05565.11 EMT53278.1 - 0.1 12.6 0.2 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Siphovirus Gp157 MobB PF03205.14 EMT53279.1 - 3.9e-39 133.6 0.0 4.7e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EMT53279.1 - 0.00062 19.4 0.0 0.0019 17.8 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 EMT53279.1 - 0.0011 19.0 0.0 0.0017 18.4 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 EMT53279.1 - 0.0052 15.8 0.1 0.0065 15.5 0.1 1.4 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 EMT53279.1 - 0.041 13.5 0.1 0.063 12.9 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EMT53279.1 - 0.11 12.2 0.1 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EMT53279.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 NTPase QRPTase_C PF01729.19 EMT53279.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain ATP_bind_1 PF03029.17 EMT53279.1 - 0.23 11.2 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MoeA_N PF03453.17 EMT53280.1 - 5.6e-44 149.7 1.5 7.5e-44 149.3 1.5 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EMT53280.1 - 2.1e-15 56.6 0.0 3.6e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 EMT53280.1 - 1.3e-09 38.1 0.0 5e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Molybdopterin PF00384.22 EMT53281.1 - 4.5e-37 128.0 0.0 6.6e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EMT53281.1 - 4.9e-11 42.6 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Formyl_trans_C PF02911.18 EMT53281.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain DUF2294 PF10057.9 EMT53282.1 - 1.3e-32 112.3 0.0 1.4e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2294) Protamine_like PF06382.11 EMT53282.1 - 0.0048 17.1 0.0 0.0075 16.5 0.0 1.5 1 1 0 1 1 1 1 Protamine and protamine like Amidohydro_3 PF07969.11 EMT53282.1 - 0.046 13.2 0.0 0.049 13.1 0.0 1.0 1 0 0 1 1 1 0 Amidohydrolase family MFS_1 PF07690.16 EMT53283.1 - 4.2e-42 144.3 63.3 3.6e-39 134.7 46.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OAD_gamma PF04277.13 EMT53283.1 - 0.0023 18.5 0.5 0.37 11.4 0.3 3.1 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain DUF2304 PF10066.9 EMT53283.1 - 0.13 12.5 0.2 0.13 12.5 0.2 4.3 4 1 1 5 5 5 0 Uncharacterized conserved protein (DUF2304) FdhD-NarQ PF02634.15 EMT53284.1 - 7.7e-77 258.2 0.0 8.8e-77 258.0 0.0 1.0 1 0 0 1 1 1 1 FdhD/NarQ family TA_inhibitor PF17574.2 EMT53284.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) NTP_transf_3 PF12804.7 EMT53285.1 - 1.7e-19 70.7 0.2 2.2e-19 70.4 0.2 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain MCPsignal PF00015.21 EMT53286.1 - 7.3e-45 152.9 23.2 7.3e-45 152.9 23.2 3.9 1 1 2 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain sCache_3_3 PF17202.4 EMT53286.1 - 2.4e-34 118.0 1.1 7e-34 116.5 1.1 1.9 1 0 0 1 1 1 1 Single cache domain 3 Cache_3-Cache_2 PF17201.4 EMT53286.1 - 9.6e-25 87.4 1.6 9.6e-25 87.4 1.6 2.8 2 1 0 3 3 3 1 Cache 3/Cache 2 fusion domain sCache_3_2 PF17203.4 EMT53286.1 - 1.6e-11 44.5 0.2 1.6e-11 44.5 0.2 3.5 4 1 0 4 4 4 1 Single cache domain 3 HAMP PF00672.25 EMT53286.1 - 5.6e-08 33.0 8.4 5.8e-08 33.0 0.0 4.8 7 0 0 7 7 7 1 HAMP domain dCache_3 PF14827.6 EMT53286.1 - 3.4e-07 30.2 0.1 3.4e-07 30.2 0.1 3.0 3 1 0 3 3 3 1 Double sensory domain of two-component sensor kinase DUF948 PF06103.11 EMT53286.1 - 3.9e-06 27.0 25.2 0.0059 16.8 1.0 5.6 3 2 2 5 5 5 3 Bacterial protein of unknown function (DUF948) Arfaptin PF06456.13 EMT53286.1 - 0.0089 15.6 14.7 1.3 8.6 1.0 3.7 2 1 1 3 3 3 3 Arfaptin-like domain YppG PF14179.6 EMT53286.1 - 0.033 14.9 0.1 0.082 13.6 0.1 1.7 1 0 0 1 1 1 0 YppG-like protein DUF1664 PF07889.12 EMT53286.1 - 0.55 10.3 18.4 6.7 6.8 1.8 4.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 EMT53286.1 - 6.8 5.7 14.9 2.7 7.0 2.9 2.3 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sigma54_activat PF00158.26 EMT53287.1 - 3.3e-69 231.9 0.2 1.1e-68 230.2 0.1 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT53287.1 - 8.8e-21 74.5 0.0 2.7e-20 72.9 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain GAF_2 PF13185.6 EMT53287.1 - 2.1e-10 41.1 0.0 1.5e-09 38.3 0.0 2.2 2 0 0 2 2 2 1 GAF domain PAS PF00989.25 EMT53287.1 - 2.2e-09 37.3 0.1 9.4e-09 35.3 0.1 2.2 2 0 0 2 2 1 1 PAS fold Mg_chelatase PF01078.21 EMT53287.1 - 2.8e-07 30.1 0.4 0.011 15.2 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI PAS_4 PF08448.10 EMT53287.1 - 2.7e-06 27.6 0.3 0.00017 21.8 0.0 3.3 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 EMT53287.1 - 1.2e-05 25.5 0.0 6.2e-05 23.2 0.0 2.3 3 0 0 3 3 1 1 PAS domain PAS_8 PF13188.7 EMT53287.1 - 1.5e-05 24.9 0.0 5.7e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 PAS domain SpoVT_C PF15714.5 EMT53287.1 - 2.9e-05 24.1 0.3 0.00023 21.2 0.0 2.3 2 1 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor AAA_5 PF07728.14 EMT53287.1 - 3.7e-05 23.8 0.0 0.00011 22.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EMT53287.1 - 7.2e-05 23.2 0.1 0.00041 20.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) GAF PF01590.26 EMT53287.1 - 8.7e-05 23.2 0.0 0.00033 21.3 0.0 2.0 2 0 0 2 2 1 1 GAF domain AAA_16 PF13191.6 EMT53287.1 - 8.8e-05 23.0 0.1 0.0037 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain MCM PF00493.23 EMT53287.1 - 0.00014 21.0 0.0 0.00045 19.4 0.0 1.8 2 1 0 2 2 2 1 MCM P-loop domain Diacid_rec PF05651.13 EMT53287.1 - 0.00016 21.3 0.7 0.015 15.0 0.8 3.5 3 1 0 3 3 3 1 Putative sugar diacid recognition DUF815 PF05673.13 EMT53287.1 - 0.0044 16.2 0.0 0.0085 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EMT53287.1 - 0.0089 15.8 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein HTH_8 PF02954.19 EMT53287.1 - 0.028 14.2 0.1 0.088 12.6 0.1 1.9 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family AAA_22 PF13401.6 EMT53287.1 - 0.034 14.4 0.6 0.36 11.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 EMT53287.1 - 0.036 14.2 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EMT53287.1 - 0.039 13.2 0.1 0.073 12.3 0.1 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 EMT53287.1 - 0.077 12.7 0.2 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EMT53287.1 - 0.086 12.3 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 EMT53287.1 - 0.094 13.0 1.5 29 5.0 0.0 3.3 3 1 0 3 3 3 0 AAA domain HTH_22 PF13309.6 EMT53287.1 - 0.11 12.6 0.2 0.49 10.5 0.1 2.2 2 0 0 2 2 2 0 HTH domain HTH_50 PF18024.1 EMT53287.1 - 0.14 11.8 0.3 0.45 10.1 0.3 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain ATP-synt_ab PF00006.25 EMT53287.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Fur_reg_FbpB PF13040.6 EMT53287.1 - 0.57 9.8 2.5 0.46 10.1 0.1 2.1 2 0 0 2 2 1 0 Fur-regulated basic protein B ABC_tran PF00005.27 EMT53288.1 - 1.9e-36 125.6 0.0 4.4e-36 124.4 0.0 1.6 2 0 0 2 2 2 1 ABC transporter TOBE_2 PF08402.10 EMT53288.1 - 1.5e-13 50.7 0.1 4.4e-13 49.2 0.1 1.9 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 EMT53288.1 - 6e-05 23.0 0.1 0.032 14.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EMT53288.1 - 0.00017 21.6 0.0 0.00028 20.9 0.0 1.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EMT53288.1 - 0.00034 21.0 0.1 0.00073 20.0 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT53288.1 - 0.00044 20.5 1.4 0.0024 18.1 1.4 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EMT53288.1 - 0.00051 20.5 0.3 0.077 13.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 EMT53288.1 - 0.00061 19.3 0.3 0.0026 17.2 0.3 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain PhoH PF02562.16 EMT53288.1 - 0.0074 15.8 0.6 2.2 7.7 0.0 2.5 3 0 0 3 3 3 2 PhoH-like protein AAA_25 PF13481.6 EMT53288.1 - 0.014 14.9 0.6 0.42 10.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain sCache_3_2 PF17203.4 EMT53288.1 - 0.021 14.9 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Single cache domain 3 RsgA_GTPase PF03193.16 EMT53288.1 - 0.036 14.0 0.3 0.09 12.7 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 EMT53288.1 - 0.11 12.7 1.3 0.59 10.4 0.5 2.5 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EMT53288.1 - 0.23 11.2 1.0 3.1 7.5 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EMT53288.1 - 5.2 7.5 4.9 15 6.0 4.9 1.8 1 1 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 EMT53289.1 - 2.5e-16 60.0 17.7 2.5e-16 60.0 17.7 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component NUDIX PF00293.28 EMT53290.1 - 1.2e-16 60.9 0.2 1.6e-16 60.5 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain Aminotran_3 PF00202.21 EMT53291.1 - 7.5e-98 327.8 0.0 9.8e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMT53291.1 - 0.0071 15.6 0.0 0.033 13.3 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II GntR PF00392.21 EMT53291.1 - 0.051 13.2 0.0 26 4.6 0.0 3.2 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family Ferritin PF00210.24 EMT53292.1 - 4.3e-34 117.5 0.7 4.6e-34 117.4 0.7 1.0 1 0 0 1 1 1 1 Ferritin-like domain DUF1804 PF08822.11 EMT53292.1 - 0.023 14.7 0.2 0.04 13.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) VPS28 PF03997.12 EMT53292.1 - 0.027 14.2 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 VPS28 protein DUF155 PF02582.14 EMT53292.1 - 0.13 12.4 1.4 1.3 9.1 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 TelA PF05816.11 EMT53293.1 - 0.0068 15.5 0.3 0.0087 15.2 0.3 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) TauE PF01925.19 EMT53294.1 - 9.2e-48 162.9 32.3 1e-47 162.8 32.3 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE CBP_BcsF PF11120.8 EMT53294.1 - 0.041 14.0 0.2 0.17 12.0 0.2 2.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF ABC_tran PF00005.27 EMT53295.1 - 6e-52 175.8 1.1 2.6e-27 96.0 0.0 3.1 4 0 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 EMT53295.1 - 8.3e-17 61.9 18.1 0.001 19.0 0.9 4.7 3 2 0 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_CTD PF16326.5 EMT53295.1 - 6.9e-16 58.3 8.2 6.9e-16 58.3 8.2 3.8 4 0 0 4 4 2 1 ABC transporter C-terminal domain ABC_tran_Xtn PF12848.7 EMT53295.1 - 9.9e-16 57.6 33.3 2.3e-14 53.2 4.9 4.1 3 1 2 5 5 4 2 ABC transporter SMC_N PF02463.19 EMT53295.1 - 7.4e-11 41.9 3.3 0.0016 17.9 0.9 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 EMT53295.1 - 8.3e-08 32.5 1.5 0.00053 20.1 0.0 3.1 3 0 0 3 3 3 2 Dynamin family AAA_29 PF13555.6 EMT53295.1 - 6.6e-07 29.0 0.9 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EMT53295.1 - 2e-06 27.8 0.1 0.0056 16.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EMT53295.1 - 2.2e-06 28.0 1.1 0.62 10.3 1.1 3.6 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EMT53295.1 - 9.7e-06 25.6 0.2 0.048 13.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EMT53295.1 - 1.5e-05 25.5 9.6 0.011 16.1 0.0 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 EMT53295.1 - 1.9e-05 24.5 3.2 0.86 9.3 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 EMT53295.1 - 3.5e-05 23.7 0.4 0.16 11.7 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.6 EMT53295.1 - 5.1e-05 23.8 1.1 0.31 11.6 0.0 3.5 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 EMT53295.1 - 0.00088 19.2 0.1 0.51 10.2 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_28 PF13521.6 EMT53295.1 - 0.00094 19.5 6.7 0.15 12.3 0.0 3.7 3 1 0 4 4 3 2 AAA domain AAA PF00004.29 EMT53295.1 - 0.001 19.5 0.0 4.5 7.7 0.0 3.5 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EMT53295.1 - 0.0016 18.2 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EMT53295.1 - 0.0049 17.4 0.0 0.0049 17.4 0.0 4.4 4 1 0 4 4 4 1 AAA domain AAA_14 PF13173.6 EMT53295.1 - 0.0084 16.2 0.1 1 9.4 0.0 3.5 4 0 0 4 4 4 1 AAA domain Cytidylate_kin PF02224.18 EMT53295.1 - 0.0091 15.7 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase AAA_19 PF13245.6 EMT53295.1 - 0.011 16.1 1.0 0.74 10.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EMT53295.1 - 0.011 15.7 0.5 2 8.4 0.1 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EMT53295.1 - 0.012 16.0 0.0 0.4 11.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase CCM2_C PF16545.5 EMT53295.1 - 0.014 15.9 0.1 0.054 14.0 0.1 2.1 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology Roc PF08477.13 EMT53295.1 - 0.016 15.4 0.1 5.3 7.3 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 EMT53295.1 - 0.017 15.0 0.1 4.2 7.2 0.0 2.8 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea MeaB PF03308.16 EMT53295.1 - 0.026 13.5 7.6 0.94 8.4 0.1 3.4 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_ab PF00006.25 EMT53295.1 - 0.037 13.7 0.0 0.71 9.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF4857 PF16149.5 EMT53295.1 - 0.058 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4857) T2SSE PF00437.20 EMT53295.1 - 0.13 11.3 1.0 0.4 9.7 0.0 2.3 3 0 0 3 3 2 0 Type II/IV secretion system protein cobW PF02492.19 EMT53295.1 - 0.14 11.7 0.4 2.7 7.5 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EMT53295.1 - 0.18 11.3 0.1 24 4.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 EMT53295.1 - 0.21 11.7 6.4 0.64 10.2 0.0 3.4 4 0 0 4 4 2 0 AAA domain Mg_chelatase PF01078.21 EMT53295.1 - 0.34 10.3 1.2 15 4.9 0.1 3.0 2 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_13 PF13166.6 EMT53295.1 - 0.69 8.5 12.5 2.5 6.6 0.0 4.1 4 0 0 4 4 4 0 AAA domain KAP_NTPase PF07693.14 EMT53295.1 - 1.5 7.9 4.1 10 5.2 0.0 3.0 3 1 0 3 3 3 0 KAP family P-loop domain DUF87 PF01935.17 EMT53295.1 - 3.7 7.6 0.0 3.7 7.6 0.0 3.8 4 1 0 4 4 4 0 Helicase HerA, central domain DUF4298 PF14131.6 EMT53295.1 - 5 7.2 6.6 0.39 10.7 0.5 2.4 3 0 0 3 3 1 0 Domain of unknown function (DUF4298) CENP-F_leu_zip PF10473.9 EMT53295.1 - 8.2 6.4 14.5 0.085 12.9 2.1 2.9 3 1 0 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peripla_BP_3 PF13377.6 EMT53296.1 - 3.1e-29 102.4 0.0 2.8e-28 99.3 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 EMT53296.1 - 1e-17 63.6 0.0 4.7e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 EMT53296.1 - 2e-12 47.2 0.0 2.8e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 EMT53296.1 - 1.7e-10 40.9 0.0 4.1e-10 39.7 0.1 1.5 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_3 PF01381.22 EMT53296.1 - 0.0019 18.2 0.1 0.0041 17.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix Trp_repressor PF01371.19 EMT53296.1 - 0.066 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein HTH_23 PF13384.6 EMT53296.1 - 0.095 12.5 0.0 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain TetR_N PF00440.23 EMT53296.1 - 0.14 12.0 0.4 0.38 10.6 0.2 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family ADH_N PF08240.12 EMT53298.1 - 8.8e-36 122.1 3.5 8.8e-36 122.1 3.5 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMT53298.1 - 1.8e-25 89.4 0.0 3.2e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMT53298.1 - 3.6e-11 43.0 0.2 6.7e-11 42.1 0.2 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 EMT53298.1 - 0.012 15.8 0.1 0.022 15.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_N_assoc PF13823.6 EMT53298.1 - 0.021 14.7 0.3 0.076 13.0 0.0 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 EMT53298.1 - 0.11 11.9 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RCC1_2 PF13540.6 EMT53299.1 - 2.8e-09 36.5 0.2 9.2e-09 34.9 0.0 1.8 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EMT53299.1 - 0.011 16.3 0.2 2.5 8.8 0.0 2.6 2 1 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Transposase_mut PF00872.18 EMT53300.1 - 4.8e-20 71.8 0.0 5.7e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family IL10 PF00726.17 EMT53300.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.5 1 1 1 2 2 2 0 Interleukin 10 Coat_F PF07875.12 EMT53302.1 - 7.9e-17 61.3 5.1 1.2e-15 57.4 0.4 2.6 2 0 0 2 2 2 2 Coat F domain PdxJ PF03740.13 EMT53302.1 - 0.057 12.5 0.4 0.084 12.0 0.4 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ Ysc84 PF04366.12 EMT53302.1 - 0.13 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Las17-binding protein actin regulator Glu_synthase PF01645.17 EMT53303.1 - 5.7e-53 180.4 0.1 7.6e-53 180.0 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 EMT53303.1 - 1.1e-12 47.6 2.7 1.5e-07 30.8 0.4 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 EMT53303.1 - 4.9e-10 38.9 0.1 1.3e-06 27.7 0.0 2.4 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EMT53303.1 - 8.3e-10 38.6 0.4 1.5e-09 37.7 0.4 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Lebercilin PF15619.6 EMT53304.1 - 0.012 15.3 0.7 0.062 13.0 0.2 1.8 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease RE_R_Pab1 PF09522.10 EMT53304.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease Transcrip_reg PF01709.20 EMT53305.1 - 7.7e-83 277.6 2.9 8.6e-83 277.4 2.9 1.0 1 0 0 1 1 1 1 Transcriptional regulator NapD PF03927.13 EMT53305.1 - 0.11 12.6 2.0 0.14 12.3 0.3 2.1 2 1 0 2 2 2 0 NapD protein Usp PF00582.26 EMT53306.1 - 0.14 12.6 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Universal stress protein family NUDIX PF00293.28 EMT53307.1 - 3.9e-16 59.3 0.0 6.2e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EMT53307.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain FERM_f0 PF16511.5 EMT53307.1 - 0.084 13.2 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM Isochorismatase PF00857.20 EMT53308.1 - 2.2e-39 135.5 0.0 2.4e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family NAPRTase_N PF17767.1 EMT53309.1 - 8.1e-34 116.7 0.1 1.5e-33 115.8 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 EMT53309.1 - 1.9e-32 112.0 0.2 5.1e-32 110.6 0.2 1.8 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 EMT53309.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family CTP_transf_like PF01467.26 EMT53310.1 - 1.5e-18 67.4 0.0 1.9e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Adeno_E4_ORF3 PF06931.11 EMT53310.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein NAD_synthase PF02540.17 EMT53311.1 - 9.6e-68 227.9 0.0 1.2e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 EMT53311.1 - 0.03 14.1 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 PP-loop family QueC PF06508.13 EMT53311.1 - 0.16 11.4 0.5 0.53 9.7 0.1 2.1 3 1 0 3 3 3 0 Queuosine biosynthesis protein QueC OmdA PF13376.6 EMT53312.1 - 1.3e-18 66.7 0.0 2.4e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated DUF1801 PF08818.11 EMT53312.1 - 1.9e-16 60.4 0.7 3e-16 59.7 0.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DU1801) DUF2573 PF10835.8 EMT53313.1 - 5.6e-34 116.3 0.2 6.5e-34 116.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2573) RasGEF_N_2 PF14663.6 EMT53313.1 - 0.054 13.9 0.1 0.058 13.8 0.1 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Radical_SAM PF04055.21 EMT53314.1 - 1.9e-13 51.1 0.0 2.7e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily DUF5131 PF07505.11 EMT53314.1 - 0.0013 18.3 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF5131) MTBP_mid PF14919.6 EMT53314.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 MDM2-binding DUF1848 PF08902.11 EMT53314.1 - 1.5 8.5 5.3 31 4.2 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1848) Oxygenase-NA PF09859.9 EMT53315.1 - 3e-79 264.5 0.1 4.4e-79 264.0 0.1 1.2 1 0 0 1 1 1 1 Oxygenase, catalysing oxidative methylation of damaged DNA PhyH PF05721.13 EMT53315.1 - 0.025 14.8 0.0 0.036 14.3 0.0 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) DNA_binding_1 PF01035.20 EMT53316.1 - 8.1e-31 106.0 0.0 1.1e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 EMT53316.1 - 1.7e-09 38.4 0.0 2.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Ada_Zn_binding PF02805.16 EMT53317.1 - 6.9e-29 99.7 7.3 6.9e-29 99.7 7.3 1.8 2 0 0 2 2 2 1 Metal binding domain of Ada HTH_18 PF12833.7 EMT53317.1 - 2.3e-26 91.9 0.1 3.6e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EMT53317.1 - 1.2e-25 89.0 0.0 9.6e-12 44.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DUF4129 PF13559.6 EMT53317.1 - 0.04 14.2 0.0 2 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) UPF0302 PF08864.10 EMT53317.1 - 0.11 12.5 0.1 3 7.9 0.0 2.2 1 1 1 2 2 2 0 UPF0302 domain MgtC PF02308.16 EMT53318.1 - 1e-29 103.3 6.5 1.3e-29 103.0 6.5 1.1 1 0 0 1 1 1 1 MgtC family DUF4173 PF13777.6 EMT53318.1 - 0.049 13.1 1.3 0.089 12.2 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4173) Sacchrp_dh_C PF16653.5 EMT53319.1 - 2.1e-20 73.9 0.0 5.1e-20 72.7 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EMT53319.1 - 1.6e-12 47.8 0.1 3.1e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain OCD_Mu_crystall PF02423.15 EMT53319.1 - 0.0029 16.6 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family 3Beta_HSD PF01073.19 EMT53319.1 - 0.053 12.5 0.1 0.097 11.7 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMT53319.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding EamA PF00892.20 EMT53320.1 - 4.4e-20 72.2 34.6 1.1e-10 41.9 15.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.19 EMT53320.1 - 2.9e-10 40.7 24.5 1.2e-07 32.2 2.3 3.9 3 1 1 4 4 4 3 Small Multidrug Resistance protein TPT PF03151.16 EMT53320.1 - 4e-07 29.7 18.3 0.00011 21.7 5.1 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family SLC35F PF06027.12 EMT53320.1 - 0.0061 16.1 14.2 0.032 13.7 1.8 2.2 2 0 0 2 2 2 2 Solute carrier family 35 TMEM234 PF10639.9 EMT53320.1 - 0.014 15.4 13.6 0.057 13.5 1.8 2.6 2 1 0 2 2 2 0 Putative transmembrane family 234 EmrE PF13536.6 EMT53320.1 - 0.056 13.0 23.0 0.41 10.2 6.7 2.9 2 1 1 3 3 3 0 Putative multidrug resistance efflux transporter EutN_CcmL PF03319.13 EMT53321.1 - 2.9e-31 107.9 0.1 3.3e-31 107.7 0.1 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutN/carboxysome PTAC PF06130.12 EMT53323.1 - 1.7e-46 156.3 0.0 2e-29 101.5 0.0 2.2 2 0 0 2 2 2 2 Phosphate propanoyltransferase Molydop_binding PF01568.21 EMT53323.1 - 0.0076 16.3 0.1 4.8 7.3 0.0 2.6 2 0 0 2 2 2 2 Molydopterin dinucleotide binding domain MazE_antitoxin PF04014.18 EMT53323.1 - 0.014 15.3 0.3 2 8.4 0.1 2.5 1 1 1 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin BMC PF00936.19 EMT53324.1 - 1.4e-26 92.3 8.1 1.6e-26 92.1 8.1 1.1 1 0 0 1 1 1 1 BMC domain Aldedh PF00171.22 EMT53325.1 - 1.5e-25 89.7 6.3 6.6e-25 87.5 6.3 1.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Polysacc_deac_2 PF04748.13 EMT53325.1 - 0.028 13.6 0.1 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase BMC PF00936.19 EMT53326.1 - 1.2e-26 92.5 8.9 1.4e-26 92.2 8.9 1.0 1 0 0 1 1 1 1 BMC domain BMC PF00936.19 EMT53327.1 - 8.2e-20 70.6 4.0 1e-19 70.2 4.0 1.1 1 0 0 1 1 1 1 BMC domain Ribosomal_60s PF00428.19 EMT53327.1 - 4 8.1 9.8 0.78 10.4 0.5 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DeoRC PF00455.22 EMT53328.1 - 1.2e-43 148.8 1.5 1.6e-43 148.4 1.5 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EMT53328.1 - 4.9e-16 58.2 0.2 1.1e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain FaeA PF04703.12 EMT53328.1 - 2.5e-06 27.7 0.5 7e-06 26.3 0.2 1.9 2 0 0 2 2 2 1 FaeA-like protein HTH_11 PF08279.12 EMT53328.1 - 5.8e-06 26.1 0.2 2.1e-05 24.4 0.2 1.9 2 0 0 2 2 2 1 HTH domain GntR PF00392.21 EMT53328.1 - 0.00029 20.4 0.1 0.00054 19.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TFIIE_alpha PF02002.17 EMT53328.1 - 0.013 15.3 0.4 0.032 14.1 0.4 1.7 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_28 PF13518.6 EMT53328.1 - 0.035 14.2 0.1 0.07 13.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 EMT53328.1 - 0.067 12.8 0.3 0.17 11.4 0.3 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Asparaginase PF00710.20 EMT53328.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Asparaginase, N-terminal MarR PF01047.22 EMT53328.1 - 0.11 12.4 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.7 EMT53328.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 MarR family MerR PF00376.23 EMT53328.1 - 0.14 11.9 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 MerR family regulatory protein HTH_36 PF13730.6 EMT53328.1 - 0.15 12.1 0.4 0.81 9.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Aminotran_5 PF00266.19 EMT53329.1 - 2e-27 96.1 0.0 2.5e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EMT53329.1 - 2.1e-06 26.6 0.0 2.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EMT53329.1 - 0.0013 18.0 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1048 PF06304.11 EMT53329.1 - 0.011 16.2 0.3 0.25 11.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1048) HAD_2 PF13419.6 EMT53330.1 - 3e-10 40.5 0.0 9.4e-10 38.9 0.0 1.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMT53330.1 - 1.9e-06 28.4 0.0 6.4e-06 26.6 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMT53330.1 - 4.1e-05 23.6 0.0 0.00017 21.6 0.0 2.0 1 1 0 1 1 1 1 HAD-hyrolase-like Flagellin_IN PF07196.13 EMT53330.1 - 0.013 15.6 0.1 0.03 14.5 0.1 1.6 1 0 0 1 1 1 0 Flagellin hook IN motif BPD_transp_1 PF00528.22 EMT53331.1 - 3e-20 72.7 56.5 1.6e-12 47.5 14.1 4.0 2 2 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component Chordopox_A13L PF05961.11 EMT53331.1 - 0.048 13.9 0.2 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Chordopoxvirus A13L protein WASH-7_C PF14746.6 EMT53331.1 - 0.11 12.2 0.3 0.79 9.4 0.1 2.2 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal ABC_tran PF00005.27 EMT53332.1 - 5.9e-34 117.5 0.0 9.7e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT53332.1 - 1.5e-09 38.2 0.6 0.0013 18.6 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 EMT53332.1 - 6.8e-09 35.8 0.1 2e-08 34.2 0.0 1.9 2 0 0 2 2 1 1 TOBE domain SMC_N PF02463.19 EMT53332.1 - 1.2e-06 28.1 0.7 0.0002 20.9 0.4 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EMT53332.1 - 0.00018 20.4 0.7 0.0037 16.1 0.2 2.8 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.29 EMT53332.1 - 0.00081 19.8 0.9 0.01 16.3 0.9 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMT53332.1 - 0.00085 19.6 0.9 0.0048 17.2 0.9 2.1 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EMT53332.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EMT53332.1 - 0.002 18.6 0.1 0.0035 17.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EMT53332.1 - 0.0027 18.3 0.0 0.0063 17.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 EMT53332.1 - 0.0035 17.6 0.2 0.01 16.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EMT53332.1 - 0.0042 17.6 0.6 0.0042 17.6 0.6 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EMT53332.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 1 1 RsgA GTPase AAA_15 PF13175.6 EMT53332.1 - 0.0092 15.7 0.4 0.016 14.9 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EMT53332.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EMT53332.1 - 0.018 15.0 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EMT53332.1 - 0.025 14.3 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 EMT53332.1 - 0.034 13.9 0.4 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 EMT53332.1 - 0.035 14.0 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EMT53332.1 - 0.062 13.0 0.5 0.45 10.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EMT53332.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EMT53332.1 - 0.076 12.7 0.0 0.26 11.0 0.0 1.8 1 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMT53332.1 - 0.096 12.2 0.1 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMT53332.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EMT53332.1 - 0.15 12.2 0.3 0.39 10.9 0.3 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EMT53332.1 - 0.16 12.0 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SBP_bac_6 PF13343.6 EMT53333.1 - 3.7e-31 108.4 0.2 5.2e-31 107.9 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EMT53333.1 - 1.8e-23 83.7 1.5 2.4e-23 83.4 1.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT53333.1 - 3.7e-16 60.0 5.6 4.8e-16 59.6 5.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EMT53333.1 - 3e-12 46.8 0.0 6.3e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein LPAM_2 PF13627.6 EMT53333.1 - 0.24 11.3 3.3 0.45 10.4 3.3 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site PHP PF02811.19 EMT53334.1 - 0.00095 19.5 0.0 0.0014 19.0 0.0 1.4 1 1 0 1 1 1 1 PHP domain PHP_C PF13263.6 EMT53334.1 - 0.0017 18.1 0.0 0.0044 16.8 0.0 1.7 1 0 0 1 1 1 1 PHP-associated HTH_50 PF18024.1 EMT53334.1 - 0.091 12.4 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1445 PF07286.12 EMT53335.1 - 0.075 13.0 0.0 0.74 9.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1445) ADH_N PF08240.12 EMT53336.1 - 2.9e-29 101.1 0.0 2.9e-29 101.1 0.0 1.9 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMT53336.1 - 1.4e-12 47.7 0.7 4.2e-10 39.7 0.1 2.2 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EMT53336.1 - 1.2e-11 44.3 0.5 2.1e-11 43.6 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 EMT53336.1 - 0.0004 19.9 0.1 0.04 13.4 0.1 2.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus FtsJ PF01728.19 EMT53336.1 - 0.0061 16.7 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EMT53336.1 - 0.019 15.6 0.0 0.035 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Sacchrp_dh_NADP PF03435.18 EMT53336.1 - 0.024 14.9 0.1 0.038 14.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_11 PF08241.12 EMT53336.1 - 0.074 13.7 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAA_33 PF13671.6 EMT53337.1 - 6.3e-07 29.6 0.1 1.6e-06 28.3 0.2 1.8 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 EMT53337.1 - 1.9e-06 27.8 0.0 2.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 EMT53337.1 - 2.5e-06 27.9 0.0 3.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMT53337.1 - 3.1e-06 27.8 0.0 8.3e-06 26.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EMT53337.1 - 1.8e-05 24.1 0.0 3.1e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin APS_kinase PF01583.20 EMT53337.1 - 0.0011 18.9 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 EMT53337.1 - 0.0024 18.3 0.0 0.0029 18.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 EMT53337.1 - 0.0035 17.1 0.0 0.0078 16.0 0.0 1.5 2 0 0 2 2 2 1 Cytidylate kinase KTI12 PF08433.10 EMT53337.1 - 0.0049 16.4 0.0 0.0058 16.1 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 EMT53337.1 - 0.015 15.6 0.3 0.035 14.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EMT53337.1 - 0.022 15.0 0.0 0.037 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 EMT53337.1 - 0.028 14.3 0.1 0.068 13.0 0.0 1.6 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_23 PF13476.6 EMT53337.1 - 0.045 14.3 0.1 0.1 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 EMT53337.1 - 0.052 13.7 0.2 0.16 12.0 0.2 2.2 1 1 0 1 1 1 0 Shikimate kinase AAA_29 PF13555.6 EMT53337.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoaE PF01121.20 EMT53337.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase Ploopntkinase1 PF18748.1 EMT53337.1 - 0.079 12.5 0.0 0.83 9.1 0.0 2.1 1 1 0 1 1 1 0 P-loop Nucleotide Kinase1 AAA_14 PF13173.6 EMT53337.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EMT53337.1 - 0.14 12.1 0.1 0.27 11.1 0.1 1.7 1 1 0 1 1 1 0 NTPase HTH_18 PF12833.7 EMT53338.1 - 7.1e-22 77.5 0.1 1e-21 77.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EMT53338.1 - 2.4e-18 65.7 0.0 6.2e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family CarboxypepD_reg PF13620.6 EMT53338.1 - 0.14 12.4 0.0 0.47 10.8 0.0 1.8 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain ADH_zinc_N_2 PF13602.6 EMT53339.1 - 3.8e-17 63.6 0.8 1.1e-16 62.0 0.8 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMT53339.1 - 9.8e-14 51.4 0.2 1.8e-13 50.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMT53339.1 - 1e-12 47.9 0.1 6.6e-11 42.1 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 EMT53340.1 - 6.8e-43 146.9 51.9 6.8e-43 146.9 51.9 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT53340.1 - 5.8e-12 45.2 8.9 5.8e-12 45.2 8.9 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter LysR_substrate PF03466.20 EMT53341.1 - 2.2e-42 144.8 0.0 2.8e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT53341.1 - 3.7e-20 71.6 0.2 1e-19 70.2 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Lin0512_fam PF09585.10 EMT53342.1 - 2.8e-42 143.3 2.0 3.1e-42 143.2 2.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) MatE PF01554.18 EMT53343.1 - 3.1e-57 192.7 38.6 1.2e-29 103.0 9.5 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EMT53343.1 - 2.2e-08 34.3 16.2 2.2e-08 34.3 16.2 4.8 3 2 3 6 6 6 2 Polysaccharide biosynthesis C-terminal domain Asp4 PF16996.5 EMT53343.1 - 0.63 9.9 0.1 0.63 9.9 0.1 2.4 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 DUF2919 PF11143.8 EMT53343.1 - 6.5 7.1 12.1 0.27 11.6 3.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) HTH_3 PF01381.22 EMT53345.1 - 3.5e-12 46.2 0.0 4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EMT53345.1 - 5.2e-09 36.3 0.0 5.9e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EMT53345.1 - 8e-07 29.0 0.0 9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EMT53345.1 - 0.00011 22.6 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EMT53345.1 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 EMT53345.1 - 0.042 13.4 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding UME PF08064.13 EMT53345.1 - 0.045 13.7 0.0 0.054 13.4 0.0 1.1 1 0 0 1 1 1 0 UME (NUC010) domain MqsA_antitoxin PF15731.5 EMT53345.1 - 0.077 13.1 0.0 0.085 13.0 0.0 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_37 PF13744.6 EMT53345.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_2 PF07719.17 EMT53346.1 - 3.3e-07 29.9 1.7 0.065 13.4 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMT53346.1 - 2.4e-05 24.0 8.4 0.032 14.1 0.2 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMT53346.1 - 6.8e-05 23.1 0.7 0.41 11.0 0.5 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMT53346.1 - 0.00026 20.8 3.2 0.011 15.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMT53346.1 - 0.0043 17.2 7.2 0.073 13.3 0.3 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMT53346.1 - 0.018 14.7 0.5 3.6 7.4 0.0 3.8 4 1 0 4 4 4 0 TPR repeat TPR_14 PF13428.6 EMT53346.1 - 0.028 15.2 0.1 30 5.8 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EMT53346.1 - 0.052 13.6 0.5 12 6.0 0.1 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 EMT53346.1 - 0.066 13.5 0.1 0.79 10.1 0.0 2.7 3 0 0 3 3 3 0 PPR repeat TPR_6 PF13174.6 EMT53346.1 - 0.09 13.5 1.1 2 9.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat NTP_transf_2 PF01909.23 EMT53347.1 - 2.3e-10 40.6 0.0 5.5e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EMT53347.1 - 5.3e-09 36.1 0.0 1.2e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase DUF4037 PF13228.6 EMT53347.1 - 0.0027 18.5 0.1 0.0048 17.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4037) DUF4064 PF13273.6 EMT53348.1 - 0.032 14.5 2.8 0.042 14.1 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3270 PF11674.8 EMT53348.1 - 0.24 11.6 6.1 0.47 10.7 6.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3270) Aldo_ket_red PF00248.21 EMT53349.1 - 8.1e-62 209.1 0.0 9.6e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 2TM PF13239.6 EMT53350.1 - 0.06 13.6 2.7 0.072 13.4 2.7 1.2 1 0 0 1 1 1 0 2TM domain GWT1 PF06423.12 EMT53350.1 - 0.15 12.1 1.8 0.16 12.1 1.8 1.1 1 0 0 1 1 1 0 GWT1 Sdh_cyt PF01127.22 EMT53350.1 - 0.19 11.8 6.9 0.23 11.5 6.9 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2304 PF10066.9 EMT53350.1 - 0.37 11.0 9.6 1.4 9.2 9.6 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Spore_permease PF03845.13 EMT53351.1 - 2.6e-74 249.9 24.4 3.2e-74 249.7 24.4 1.1 1 0 0 1 1 1 1 Spore germination protein Collectrin PF16959.5 EMT53351.1 - 0.64 9.8 4.2 1 9.1 2.4 2.1 2 0 0 2 2 2 0 Renal amino acid transporter Spore_GerAC PF05504.11 EMT53352.1 - 4.2e-38 131.1 0.0 5.9e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal P-mevalo_kinase PF04275.14 EMT53352.1 - 0.048 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphomevalonate kinase GerA PF03323.13 EMT53353.1 - 2.1e-188 626.6 1.4 2.4e-188 626.4 1.4 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein Sigma70_r2 PF04542.14 EMT53354.1 - 4.9e-10 39.0 0.2 7.7e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Lactamase_B_2 PF12706.7 EMT53355.1 - 3.8e-40 137.5 0.0 4.9e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMT53355.1 - 2.1e-26 92.8 0.0 2.7e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMT53355.1 - 0.00012 22.2 1.0 0.006 16.6 0.5 2.5 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily TetR_N PF00440.23 EMT53356.1 - 1.1e-16 60.4 0.6 1.9e-16 59.6 0.6 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_36 PF18598.1 EMT53356.1 - 0.00025 21.0 0.4 0.00041 20.3 0.4 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 EMT53356.1 - 0.0042 17.3 0.5 0.0089 16.2 0.5 1.5 1 1 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_24 PF17932.1 EMT53356.1 - 0.0047 17.2 0.1 0.017 15.4 0.1 1.9 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_26 PF17934.1 EMT53356.1 - 0.15 12.4 0.1 0.5 10.7 0.0 1.9 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DoxX_2 PF13564.6 EMT53357.1 - 5.4e-22 77.8 9.7 6.1e-22 77.7 9.7 1.0 1 0 0 1 1 1 1 DoxX-like family DoxX PF07681.12 EMT53357.1 - 0.00081 19.9 7.4 0.00081 19.9 7.4 1.6 2 0 0 2 2 2 1 DoxX FUSC-like PF12805.7 EMT53357.1 - 0.91 8.5 4.4 1.1 8.3 4.4 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Pox_I5 PF04713.12 EMT53357.1 - 1.2 9.2 6.5 1 9.4 0.8 2.4 1 1 1 2 2 2 0 Poxvirus protein I5 SLH PF00395.20 EMT53358.1 - 3.1e-29 100.7 2.2 8.4e-13 48.1 0.1 3.8 3 0 0 3 3 3 2 S-layer homology domain TLP1_add_C PF18313.1 EMT53358.1 - 0.0037 17.2 0.2 0.86 9.6 0.0 3.2 3 0 0 3 3 3 1 Thiolase-like protein type 1 additional C-terminal domain BiPBP_C PF06832.12 EMT53358.1 - 0.09 12.8 0.0 0.7 10.0 0.0 2.6 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family DUF2283 PF10049.9 EMT53358.1 - 0.3 11.3 3.2 17 5.8 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2283) FTP PF07504.13 EMT53358.1 - 2.8 7.8 8.5 6.3 6.7 0.1 5.3 6 0 0 6 6 6 0 Fungalysin/Thermolysin Propeptide Motif IF3_N PF05198.16 EMT53359.1 - 7.7e-19 67.7 0.3 7.7e-19 67.7 0.3 1.9 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 EMT53359.1 - 4.4e-15 55.4 0.2 6.9e-15 54.8 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Pannexin_like PF12534.8 EMT53359.1 - 0.019 14.1 1.1 0.024 13.7 1.1 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF3006 PF11213.8 EMT53359.1 - 0.08 13.2 0.3 0.08 13.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) SWIM PF04434.17 EMT53360.1 - 0.00018 21.1 1.2 0.00031 20.3 1.2 1.4 1 0 0 1 1 1 1 SWIM zinc finger Ku_PK_bind PF08785.11 EMT53360.1 - 0.015 15.5 1.6 0.062 13.4 0.3 2.7 2 1 0 2 2 2 0 Ku C terminal domain like SNF2_N PF00176.23 EMT53361.1 - 1.3e-57 195.2 0.0 1.9e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3670 PF12419.8 EMT53361.1 - 3.9e-34 117.4 0.9 3.9e-34 117.4 0.9 1.8 2 0 0 2 2 2 1 SNF2 Helicase protein Helicase_C PF00271.31 EMT53361.1 - 4.5e-18 65.6 0.0 7.5e-17 61.7 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMT53361.1 - 0.0035 17.3 0.0 0.0061 16.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1801 PF08818.11 EMT53363.1 - 2.7e-06 27.8 0.0 3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DU1801) Endonuclease_NS PF01223.23 EMT53364.1 - 6.6e-35 121.0 0.0 8.5e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease SHMT PF00464.19 EMT53365.1 - 2.3e-52 178.0 0.0 2.9e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EMT53365.1 - 0.00036 19.8 0.0 0.00046 19.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.13 EMT53365.1 - 0.018 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase GntR PF00392.21 EMT53366.1 - 2.1e-20 72.1 0.1 8e-20 70.3 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 EMT53366.1 - 3.4e-19 69.5 9.0 6e-19 68.7 9.0 1.4 1 0 0 1 1 1 1 FCD domain HTH_24 PF13412.6 EMT53366.1 - 2.8e-06 26.8 0.0 5.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EMT53366.1 - 1.5e-05 24.8 0.0 3.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 EMT53366.1 - 1.8e-05 24.5 0.5 3.6e-05 23.5 0.1 1.7 2 0 0 2 2 1 1 MarR family Rrf2 PF02082.20 EMT53366.1 - 7.1e-05 23.1 0.0 0.0002 21.7 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 EMT53366.1 - 0.00012 22.0 0.0 0.00039 20.4 0.0 1.9 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 EMT53366.1 - 0.00022 21.1 0.0 0.00053 19.9 0.0 1.7 1 0 0 1 1 1 1 HTH domain Fe_dep_repress PF01325.19 EMT53366.1 - 0.00026 21.1 0.0 0.00057 20.0 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 EMT53366.1 - 0.00026 20.8 0.0 0.0007 19.5 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_AsnC-type PF13404.6 EMT53366.1 - 0.001 18.9 0.1 0.0031 17.3 0.1 1.9 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 EMT53366.1 - 0.0025 17.6 0.0 0.0071 16.2 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 EMT53366.1 - 0.0045 16.8 0.1 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain FaeA PF04703.12 EMT53366.1 - 0.0052 17.1 0.0 0.028 14.8 0.0 2.0 2 0 0 2 2 2 1 FaeA-like protein HTH_29 PF13551.6 EMT53366.1 - 0.01 15.8 0.2 0.094 12.8 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HemN_C PF06969.16 EMT53366.1 - 0.016 15.3 0.0 0.048 13.7 0.0 1.9 1 0 0 1 1 1 0 HemN C-terminal domain PaaX PF07848.12 EMT53366.1 - 0.021 15.0 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 PaaX-like protein DUF977 PF06163.11 EMT53366.1 - 0.026 14.5 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) HTH_41 PF14502.6 EMT53366.1 - 0.026 14.2 0.0 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.6 EMT53366.1 - 0.027 15.0 0.0 0.058 13.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_10 PF04967.12 EMT53366.1 - 0.032 14.0 0.1 0.39 10.5 0.0 2.7 2 0 0 2 2 2 0 HTH DNA binding domain HTH_CodY PF08222.11 EMT53366.1 - 0.034 13.7 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 1 0 CodY helix-turn-helix domain HrcA_DNA-bdg PF03444.15 EMT53366.1 - 0.036 13.7 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding PCI PF01399.27 EMT53366.1 - 0.048 14.2 0.1 6.8 7.3 0.1 2.2 2 0 0 2 2 2 0 PCI domain HTH_20 PF12840.7 EMT53366.1 - 0.052 13.6 0.1 0.2 11.7 0.0 2.0 2 0 0 2 2 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 EMT53366.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit AbiEi_4 PF13338.6 EMT53366.1 - 0.099 12.8 0.2 0.87 9.8 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin HTH_23 PF13384.6 EMT53366.1 - 0.11 12.3 0.1 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain DUF2250 PF10007.9 EMT53366.1 - 0.11 12.6 0.0 0.42 10.7 0.0 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) YitT_membrane PF02588.15 EMT53367.1 - 9e-67 224.4 25.1 1.2e-66 224.0 25.1 1.2 1 0 0 1 1 1 1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DUF2179 PF10035.9 EMT53367.1 - 5e-23 80.6 0.1 8.6e-23 79.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2179) Radical_SAM PF04055.21 EMT53368.1 - 4.3e-18 66.3 0.0 1.2e-17 64.8 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 EMT53368.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_14 PF13394.6 EMT53368.1 - 0.13 12.5 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain NO_synthase PF02898.15 EMT53370.1 - 1.8e-163 543.8 1.3 2e-163 543.6 1.3 1.0 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain Aldedh PF00171.22 EMT53371.1 - 9.3e-184 611.2 0.0 1e-183 611.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3156 PF11354.8 EMT53372.1 - 0.031 14.2 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3156) Rep_trans PF02486.19 EMT53372.1 - 0.077 12.7 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Replication initiation factor AA_permease_2 PF13520.6 EMT53373.1 - 9.9e-35 120.2 48.6 1.3e-34 119.8 48.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMT53373.1 - 1.6e-15 56.7 48.0 7.2e-15 54.5 48.0 1.8 1 1 0 1 1 1 1 Amino acid permease DUF4579 PF15158.6 EMT53373.1 - 0.56 10.0 2.9 0.58 9.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) Fe-ADH PF00465.19 EMT53374.1 - 1.5e-124 415.5 0.7 1.7e-124 415.4 0.7 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMT53374.1 - 3.2e-18 66.3 1.5 2.8e-11 43.6 0.1 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 EMT53374.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein DinB_2 PF12867.7 EMT53375.1 - 1.9e-15 57.5 0.1 2.3e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 EMT53375.1 - 2.5e-06 28.0 0.3 3.1e-06 27.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF664) DUF1572 PF07609.11 EMT53375.1 - 2.9e-05 23.9 0.4 4.4e-05 23.3 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1572) DinB PF05163.12 EMT53375.1 - 0.0017 18.3 0.4 0.0028 17.6 0.4 1.4 1 1 0 1 1 1 1 DinB family MDMPI_N PF11716.8 EMT53375.1 - 0.0023 18.6 1.1 0.01 16.6 1.1 2.3 1 1 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain Bac_luciferase PF00296.20 EMT53376.1 - 4.1e-62 210.4 0.7 5.7e-62 209.9 0.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase PAS_3 PF08447.12 EMT53376.1 - 0.085 13.2 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 PAS fold Peptidase_M20 PF01546.28 EMT53377.1 - 1.2e-33 116.6 0.6 1.8e-33 116.0 0.6 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT53377.1 - 1.1e-10 41.4 0.1 3.2e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Acetyltransf_1 PF00583.25 EMT53378.1 - 7.1e-11 42.4 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT53378.1 - 1.2e-10 41.7 0.0 2.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT53378.1 - 2.1e-08 34.2 0.0 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMT53378.1 - 0.0013 18.8 0.0 0.0041 17.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT53378.1 - 0.0025 18.0 0.0 0.003 17.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT53378.1 - 0.044 13.7 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein ABC_tran PF00005.27 EMT53379.1 - 2.4e-33 115.6 0.0 3.1e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT53379.1 - 7.6e-13 48.9 0.0 4.3e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT53379.1 - 3.4e-08 33.2 0.1 3.5e-06 26.6 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMT53379.1 - 9.8e-06 26.2 0.3 1.8e-05 25.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMT53379.1 - 3.4e-05 24.3 0.0 4.8e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.6 EMT53379.1 - 7.6e-05 21.6 0.0 0.028 13.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EMT53379.1 - 0.00069 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EMT53379.1 - 0.0015 17.4 0.3 0.8 8.4 0.0 2.9 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 EMT53379.1 - 0.0025 18.1 0.2 0.0064 16.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMT53379.1 - 0.0037 17.0 0.0 0.0089 15.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EMT53379.1 - 0.0046 16.9 0.1 0.014 15.4 0.1 1.9 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EMT53379.1 - 0.0096 15.8 0.1 0.02 14.8 0.1 1.5 1 1 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 EMT53379.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 EMT53379.1 - 0.011 16.2 0.1 1.9 8.9 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EMT53379.1 - 0.019 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EMT53379.1 - 0.026 14.7 0.3 0.069 13.3 0.2 1.7 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 EMT53379.1 - 0.029 13.4 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EMT53379.1 - 0.047 13.9 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EMT53379.1 - 0.048 13.2 0.1 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EMT53379.1 - 0.057 13.7 0.2 0.074 13.4 0.2 1.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMT53379.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EMT53379.1 - 0.061 13.2 0.3 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 EMT53379.1 - 0.095 12.1 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EMT53379.1 - 0.11 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 EMT53379.1 - 0.12 11.6 0.1 0.24 10.6 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.6 EMT53379.1 - 0.12 12.7 0.1 2.3 8.5 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RYDR_ITPR PF01365.21 EMT53379.1 - 0.14 11.6 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 RIH domain G-alpha PF00503.20 EMT53379.1 - 0.14 11.3 0.0 0.32 10.1 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.6 EMT53379.1 - 0.2 12.2 0.3 0.54 10.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 EMT53380.1 - 1e-19 71.0 16.3 1e-19 71.0 16.3 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EMT53381.1 - 6.8e-16 58.5 17.4 9.5e-16 58.1 17.4 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component LST1 PF05083.13 EMT53381.1 - 0.061 13.6 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 LST-1 protein SBP_bac_3 PF00497.20 EMT53382.1 - 9.6e-51 172.4 0.4 1.1e-50 172.1 0.4 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 EMT53382.1 - 4.7e-07 30.0 0.1 7.7e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 EMT53382.1 - 0.00073 19.2 0.1 0.0012 18.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LysR_substrate PF03466.20 EMT53382.1 - 0.048 13.0 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 LysR substrate binding domain Bac_luciferase PF00296.20 EMT53383.1 - 3.8e-40 138.3 1.4 5.7e-40 137.7 1.4 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase LysR_substrate PF03466.20 EMT53384.1 - 4.1e-36 124.3 0.0 5.7e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT53384.1 - 3.4e-18 65.3 0.0 6.3e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EMT53384.1 - 0.0046 16.7 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain MarR PF01047.22 EMT53385.1 - 1.8e-13 50.2 0.0 3.1e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EMT53385.1 - 1e-11 44.5 0.0 1.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EMT53385.1 - 9.3e-10 38.9 0.0 1.9e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 EMT53385.1 - 9.2e-07 29.0 0.0 2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 EMT53385.1 - 3.6e-05 23.2 0.1 6.8e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding B-block_TFIIIC PF04182.12 EMT53385.1 - 0.00085 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Penicillinase_R PF03965.16 EMT53385.1 - 0.0022 18.3 0.8 0.0047 17.3 0.7 1.6 1 1 0 1 1 1 1 Penicillinase repressor TrmB PF01978.19 EMT53385.1 - 0.0023 17.8 0.1 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB FeoC PF09012.10 EMT53385.1 - 0.0049 16.9 0.3 0.013 15.6 0.1 2.0 1 1 0 1 1 1 1 FeoC like transcriptional regulator HTH_Crp_2 PF13545.6 EMT53385.1 - 0.0051 16.8 0.2 0.013 15.5 0.2 1.7 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 EMT53385.1 - 0.0054 16.9 0.1 0.012 15.7 0.0 1.6 2 0 0 2 2 1 1 Winged helix DNA-binding domain NA37 PF04245.13 EMT53385.1 - 0.0059 16.1 0.2 0.0086 15.6 0.2 1.2 1 0 0 1 1 1 1 37-kD nucleoid-associated bacterial protein RGS-like PF09128.11 EMT53385.1 - 0.0087 15.8 2.5 0.011 15.4 2.5 1.2 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain RP-C PF03428.13 EMT53385.1 - 0.011 15.4 0.2 0.021 14.5 0.2 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain HTH_IclR PF09339.10 EMT53385.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF1400 PF07176.11 EMT53385.1 - 0.024 14.9 1.6 0.46 10.8 0.2 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) TFIIE-A_C PF11521.8 EMT53385.1 - 0.024 14.9 0.2 0.038 14.3 0.2 1.6 1 1 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha LuxT_C PF18285.1 EMT53385.1 - 0.057 14.0 0.1 0.11 13.1 0.1 1.6 1 1 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain HTH_micro PF17007.5 EMT53385.1 - 0.059 12.2 0.2 0.072 11.9 0.2 1.2 1 0 0 1 1 1 0 HTH-like HxlR PF01638.17 EMT53385.1 - 0.074 12.9 0.6 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 HxlR-like helix-turn-helix DUF5343 PF17278.2 EMT53385.1 - 0.08 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5343) HTH_20 PF12840.7 EMT53385.1 - 0.08 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TipAS PF07739.13 EMT53385.1 - 0.11 13.1 0.3 0.21 12.2 0.3 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain MFS_1 PF07690.16 EMT53386.1 - 4.6e-47 160.7 45.0 7.6e-47 159.9 45.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMT53386.1 - 6.2e-09 35.6 31.4 9.3e-09 35.0 31.4 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 EMT53386.1 - 1e-08 34.5 10.2 1e-08 34.5 10.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Chromate_transp PF02417.15 EMT53387.1 - 1.8e-74 249.1 33.1 2.1e-40 138.4 13.9 2.2 2 0 0 2 2 2 2 Chromate transporter AzlD PF05437.12 EMT53387.1 - 1.4 9.2 25.0 0.2 11.9 9.6 2.8 2 1 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Aldo_ket_red PF00248.21 EMT53388.1 - 1.7e-53 181.7 0.9 1.7e-51 175.2 0.9 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF2309 PF10070.9 EMT53388.1 - 0.038 12.3 0.1 0.039 12.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) MFS_1 PF07690.16 EMT53389.1 - 1.2e-44 152.7 62.1 3.6e-41 141.3 47.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT53389.1 - 1.1e-09 37.7 50.5 4e-09 35.9 17.9 3.0 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 EMT53389.1 - 5.7e-08 32.5 43.2 7.1e-08 32.1 43.2 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB HxlR PF01638.17 EMT53390.1 - 7.1e-39 131.5 0.2 9.5e-39 131.1 0.2 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.22 EMT53390.1 - 0.086 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 MarR family Utp13 PF08625.11 EMT53390.1 - 0.089 12.7 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain HTH_20 PF12840.7 EMT53390.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HlyD_D23 PF16576.5 EMT53391.1 - 9.2e-27 93.7 16.6 1.8e-19 69.8 6.3 2.2 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EMT53391.1 - 1.5e-18 67.4 15.1 1.6e-16 60.9 3.8 3.6 4 1 0 4 4 4 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EMT53391.1 - 1.9e-14 53.2 0.3 1.9e-14 53.2 0.3 4.4 4 1 0 4 4 4 1 Biotin-lipoyl like HlyD_2 PF12700.7 EMT53391.1 - 4.9e-06 25.5 3.0 4.9e-06 25.5 3.0 2.3 1 1 1 2 2 2 1 HlyD family secretion protein OEP PF02321.18 EMT53391.1 - 4.9e-05 23.2 20.2 4.9e-05 23.2 20.2 2.3 1 1 1 2 2 2 2 Outer membrane efflux protein Biotin_lipoyl PF00364.22 EMT53391.1 - 0.014 15.2 13.5 0.072 12.9 0.1 4.6 5 0 0 5 5 5 0 Biotin-requiring enzyme SHOCT PF09851.9 EMT53391.1 - 0.019 14.7 0.0 0.053 13.3 0.0 1.8 1 0 0 1 1 1 0 Short C-terminal domain DUF2505 PF10698.9 EMT53391.1 - 0.026 14.7 4.9 0.13 12.3 4.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2505) HlyD PF00529.20 EMT53391.1 - 0.043 13.7 1.5 0.16 11.8 1.5 2.3 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS OmpH PF03938.14 EMT53391.1 - 0.085 13.2 18.8 16 5.8 18.8 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) GvpK PF05121.12 EMT53391.1 - 0.16 12.0 1.2 0.64 10.1 0.4 2.4 1 1 1 2 2 2 0 Gas vesicle protein K Atg14 PF10186.9 EMT53391.1 - 0.33 10.0 8.6 0.51 9.4 8.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2564 PF10819.8 EMT53391.1 - 0.43 11.0 19.4 0.55 10.6 1.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2564) UPF0242 PF06785.11 EMT53391.1 - 0.64 10.1 13.6 1 9.4 13.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TFIIA PF03153.13 EMT53391.1 - 1.7 8.5 19.3 2.2 8.2 19.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ACR_tran PF00873.19 EMT53392.1 - 6.8e-249 828.5 32.2 7.7e-249 828.3 32.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EMT53392.1 - 3.6e-11 42.6 20.3 8.9e-10 38.0 3.7 3.0 3 0 0 3 3 3 2 MMPL family DUF2207 PF09972.9 EMT53392.1 - 0.033 13.0 5.9 0.2 10.4 0.3 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) MarR PF01047.22 EMT53393.1 - 2e-10 40.4 0.1 3.9e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EMT53393.1 - 5.1e-10 39.7 0.0 1.1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 EMT53393.1 - 1.9e-08 34.0 0.0 3.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 EMT53393.1 - 4.9e-06 26.2 0.0 8.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 EMT53393.1 - 8.2e-06 25.6 0.2 7.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 EMT53393.1 - 2.2e-05 24.2 0.2 5.5e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EMT53393.1 - 0.0017 17.9 0.4 0.0037 16.8 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_45 PF14947.6 EMT53393.1 - 0.0025 17.8 0.0 0.0068 16.4 0.0 1.8 1 1 0 1 1 1 1 Winged helix-turn-helix Penicillinase_R PF03965.16 EMT53393.1 - 0.021 15.1 0.0 0.034 14.5 0.0 1.6 1 1 0 1 1 1 0 Penicillinase repressor NRho PF16733.5 EMT53393.1 - 0.072 13.2 0.2 0.86 9.7 0.0 2.2 2 0 0 2 2 2 0 Rhomboid N-terminal domain Rrf2 PF02082.20 EMT53393.1 - 0.087 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator HisKA_3 PF07730.13 EMT53394.1 - 1.6e-17 63.8 5.8 2.9e-17 62.9 1.4 2.4 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 EMT53394.1 - 5e-06 27.0 0.0 6.6e-05 23.4 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rogdi_lz PF10259.9 EMT53394.1 - 0.0092 15.5 0.9 0.012 15.1 0.9 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein HATPase_c_2 PF13581.6 EMT53394.1 - 0.013 15.5 1.2 0.15 12.0 0.0 2.4 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain Halogen_Hydrol PF10112.9 EMT53394.1 - 0.013 15.5 0.0 0.013 15.5 0.0 2.2 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF1043 PF06295.12 EMT53394.1 - 0.029 14.4 2.6 0.051 13.6 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) SLATT_5 PF18160.1 EMT53394.1 - 0.039 13.3 0.9 1 8.6 0.0 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 HATPase_c_5 PF14501.6 EMT53394.1 - 0.12 12.3 0.0 0.41 10.6 0.0 2.0 1 1 0 1 1 1 0 GHKL domain DUF3165 PF11364.8 EMT53394.1 - 0.18 12.2 2.7 0.15 12.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) Response_reg PF00072.24 EMT53395.1 - 7.9e-28 96.9 2.1 2.1e-27 95.5 1.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 EMT53395.1 - 1.4e-20 72.5 0.0 2.4e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EMT53395.1 - 1.3e-05 24.8 0.0 2.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT53395.1 - 2.1e-05 23.9 0.3 5.6e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 B12-binding PF02310.19 EMT53395.1 - 0.017 15.1 0.2 0.095 12.7 0.1 2.0 2 0 0 2 2 2 0 B12 binding domain HTH_40 PF14493.6 EMT53395.1 - 0.056 13.9 0.1 1.8 9.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Peripla_BP_2 PF01497.18 EMT53395.1 - 0.087 12.4 0.0 0.43 10.1 0.0 2.1 2 1 1 3 3 3 0 Periplasmic binding protein HTH_30 PF13556.6 EMT53395.1 - 0.1 12.4 0.2 0.21 11.4 0.2 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MFS_1 PF07690.16 EMT53396.1 - 1.3e-57 195.4 44.4 4.5e-32 111.3 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT53396.1 - 2.3e-15 56.4 23.6 3e-06 26.4 8.6 3.4 2 2 1 3 3 3 3 Sugar (and other) transporter MFS_2 PF13347.6 EMT53396.1 - 2.9e-12 45.9 26.4 2.5e-09 36.2 11.5 2.7 1 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 EMT53396.1 - 2.4e-10 39.9 26.6 8.5e-06 24.9 1.1 3.0 1 1 2 3 3 3 3 MFS_1 like family MFS_3 PF05977.13 EMT53396.1 - 2.7e-05 22.8 17.0 0.00017 20.2 17.0 1.8 1 1 0 1 1 1 1 Transmembrane secretion effector MFS_4 PF06779.14 EMT53396.1 - 0.00014 21.3 23.5 0.017 14.4 8.7 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF1751 PF08551.10 EMT53396.1 - 0.11 13.1 0.0 0.11 13.1 0.0 3.5 4 1 0 4 4 4 0 Eukaryotic integral membrane protein (DUF1751) Amidohydro_3 PF07969.11 EMT53397.1 - 2.6e-90 304.2 0.0 3e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EMT53397.1 - 4.5e-14 52.5 0.0 4.3e-09 36.1 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family MannoseP_isomer PF01050.18 EMT53398.1 - 4.8e-22 78.5 0.8 1.2e-21 77.2 0.8 1.6 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NTP_transferase PF00483.23 EMT53398.1 - 1.4e-19 70.7 0.1 2.2e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Cupin_2 PF07883.11 EMT53398.1 - 2.6e-06 27.1 0.0 5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain CBM39 PF15886.5 EMT53398.1 - 0.02 14.8 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) AraC_binding PF02311.19 EMT53398.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain PGM_PMM_I PF02878.16 EMT53399.1 - 3.9e-40 136.8 0.1 8.1e-40 135.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EMT53399.1 - 4.1e-24 85.0 0.0 6.8e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EMT53399.1 - 4.7e-22 78.6 0.0 1.3e-21 77.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EMT53399.1 - 2.5e-08 34.0 0.0 8.9e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Glycos_transf_1 PF00534.20 EMT53400.1 - 9.3e-37 126.2 0.0 1.4e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT53400.1 - 9.2e-29 100.6 0.0 2.3e-28 99.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT53400.1 - 1.5e-22 80.4 0.2 1.5e-22 80.4 0.2 1.8 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EMT53400.1 - 7.8e-18 65.4 2.0 3.7e-17 63.2 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EMT53400.1 - 7e-06 26.3 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 CarboxypepD_reg PF13620.6 EMT53401.1 - 2e-07 31.2 0.0 3.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EMT53401.1 - 3.3e-05 23.8 0.0 5.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain SdrD_B PF17210.3 EMT53401.1 - 0.0003 21.0 0.6 0.0005 20.3 0.1 1.6 2 0 0 2 2 2 1 SdrD B-like domain Glycos_transf_1 PF00534.20 EMT53402.1 - 1.1e-27 96.7 0.0 1.6e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT53402.1 - 5.3e-19 69.0 0.0 7.8e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EMT53402.1 - 2.6e-05 24.5 0.0 6.4e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT53402.1 - 0.13 12.3 0.0 1 9.3 0.0 2.3 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Glycos_transf_2 PF00535.26 EMT53403.1 - 6.6e-22 78.1 0.0 1.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMT53403.1 - 3e-07 30.5 0.0 2.9e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EMT53403.1 - 1e-06 28.4 0.1 2.3e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 EMT53403.1 - 0.0048 16.6 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family Glyco_trans_2_3 PF13632.6 EMT53403.1 - 0.16 11.9 2.3 0.42 10.5 2.3 1.6 1 1 0 1 1 1 0 Glycosyl transferase family group 2 DGF-1_5 PF11038.8 EMT53403.1 - 0.2 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 Glycos_transf_2 PF00535.26 EMT53404.1 - 5.4e-25 88.2 0.0 7.6e-24 84.4 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_trans_1_4 PF13692.6 EMT53404.1 - 1.3e-24 87.1 0.0 3.4e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_tranf_2_3 PF13641.6 EMT53404.1 - 2.3e-16 60.4 0.0 3.8e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EMT53404.1 - 3.9e-09 36.4 0.0 7.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_1 PF00534.20 EMT53404.1 - 5.1e-08 32.6 0.0 1.6e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_tranf_2_5 PF13712.6 EMT53404.1 - 1.3e-07 31.6 0.0 8.4e-07 28.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family Glyco_trans_1_2 PF13524.6 EMT53404.1 - 0.00014 22.2 0.0 0.00043 20.6 0.0 1.8 2 0 0 2 2 1 1 Glycosyl transferases group 1 Glyco_trans_2_3 PF13632.6 EMT53404.1 - 0.0018 18.2 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 EMT53404.1 - 0.0041 17.6 0.0 0.012 16.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_4_4 PF13579.6 EMT53404.1 - 0.046 14.2 0.0 0.32 11.4 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EMT53404.1 - 0.14 12.2 0.0 0.9 9.5 0.0 2.4 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Methyltransf_33 PF10017.9 EMT53404.1 - 0.14 11.2 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Glycos_transf_1 PF00534.20 EMT53405.1 - 2.1e-34 118.5 0.0 4e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT53405.1 - 1.8e-23 83.5 0.0 8.6e-23 81.3 0.0 2.1 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT53405.1 - 5.3e-22 78.6 2.0 2.2e-21 76.6 2.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EMT53405.1 - 2.2e-16 60.7 0.0 6.3e-16 59.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 EMT53405.1 - 3.3e-06 27.0 0.5 4.9e-06 26.4 0.5 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 EMT53405.1 - 8.3e-05 22.9 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EMT53406.1 - 3.4e-27 95.1 0.0 4.9e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT53406.1 - 5.4e-21 75.4 0.1 9.1e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT53406.1 - 9.6e-10 38.7 0.0 1.6e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EMT53406.1 - 3.1e-09 37.1 0.0 6.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EMT53406.1 - 0.00011 22.7 0.0 0.00019 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain RmlD_sub_bind PF04321.17 EMT53407.1 - 2.2e-102 342.0 0.3 2.5e-102 341.8 0.3 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EMT53407.1 - 1e-27 97.2 0.3 1.4e-27 96.7 0.3 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMT53407.1 - 1.5e-17 64.0 1.7 2.1e-15 57.0 0.2 2.2 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMT53407.1 - 1.4e-15 57.2 3.0 3.5e-13 49.4 1.0 2.8 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EMT53407.1 - 7.1e-12 44.9 1.1 1.9e-10 40.2 0.1 2.2 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMT53407.1 - 4.2e-10 39.2 1.5 1.5e-08 34.1 0.3 2.6 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EMT53407.1 - 3.7e-06 26.9 1.1 1.5e-05 24.9 1.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 EMT53407.1 - 0.0084 16.2 0.2 0.024 14.8 0.1 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 EMT53407.1 - 0.03 13.8 0.7 0.43 10.0 0.3 2.6 2 1 1 3 3 3 0 short chain dehydrogenase NmrA PF05368.13 EMT53407.1 - 0.036 13.6 0.2 0.053 13.1 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family KR PF08659.10 EMT53407.1 - 0.092 12.7 0.7 0.27 11.1 0.6 1.8 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 EMT53408.1 - 5.3e-87 292.3 0.0 6.9e-87 291.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMT53408.1 - 3.1e-61 206.9 0.0 6.6e-61 205.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMT53408.1 - 2.2e-14 53.3 0.0 1.9e-12 46.9 0.0 2.8 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EMT53408.1 - 3.6e-13 49.3 0.0 9.6e-13 47.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EMT53408.1 - 6.2e-13 48.4 0.0 1.7e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EMT53408.1 - 1.4e-12 47.4 0.0 2.3e-12 46.6 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EMT53408.1 - 0.00015 21.3 0.0 0.00042 19.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EMT53408.1 - 0.0019 18.1 0.0 0.0075 16.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding dTDP_sugar_isom PF00908.17 EMT53409.1 - 2.5e-25 89.1 0.0 2.8e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase Cupin_2 PF07883.11 EMT53409.1 - 0.00064 19.4 0.1 0.25 11.1 0.0 2.2 2 0 0 2 2 2 2 Cupin domain FdtA PF05523.11 EMT53409.1 - 0.049 13.3 0.0 0.075 12.8 0.0 1.4 1 1 0 1 1 1 0 WxcM-like, C-terminal Methyltransf_23 PF13489.6 EMT53410.1 - 2.3e-05 24.3 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT53410.1 - 0.00016 22.2 0.0 0.00083 20.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT53410.1 - 0.017 15.9 0.0 0.084 13.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EMT53410.1 - 0.11 13.3 0.0 0.5 11.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_21 PF05050.12 EMT53411.1 - 1.1e-05 25.6 0.0 3.2e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase FkbM domain Met_10 PF02475.16 EMT53411.1 - 0.0063 16.3 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 EMT53411.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EMT53411.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EMT53411.1 - 0.19 11.8 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF268 PF03269.14 EMT53412.1 - 0.00015 21.7 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF268 CMAS PF02353.20 EMT53412.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EMT53412.1 - 0.011 16.5 0.0 0.02 15.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EMT53412.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glycos_transf_1 PF00534.20 EMT53413.1 - 4.6e-13 49.1 0.0 9.1e-13 48.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT53413.1 - 1.6e-11 44.8 0.0 2.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EMT53414.1 - 7.4e-49 165.6 0.0 2.5e-30 105.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT53414.1 - 2.1e-35 122.1 0.0 1.6e-22 80.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT53414.1 - 1.5e-11 44.6 0.3 5.7e-10 39.5 0.0 3.1 3 1 1 4 4 4 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EMT53414.1 - 3.6e-11 43.3 0.0 6.9e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 EMT53414.1 - 0.0062 15.3 0.0 0.018 13.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 20 GDP_Man_Dehyd PF16363.5 EMT53415.1 - 8.5e-86 288.4 0.0 2e-85 287.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMT53415.1 - 3.2e-55 187.2 0.0 3.7e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMT53415.1 - 7.8e-11 41.6 0.0 6e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EMT53415.1 - 1.7e-07 30.6 0.0 3.3e-07 29.7 0.0 1.4 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EMT53415.1 - 1.6e-05 24.0 0.0 2.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMT53415.1 - 0.00025 20.3 0.0 0.00041 19.6 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EMT53415.1 - 0.0098 15.8 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EMT53415.1 - 0.16 11.4 0.0 0.34 10.3 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Glycos_transf_1 PF00534.20 EMT53416.1 - 6.8e-12 45.2 0.0 1.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT53416.1 - 1.1e-08 35.6 0.0 1.5e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT53416.1 - 0.00099 19.1 0.0 0.044 13.8 0.0 2.4 1 1 1 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EMT53416.1 - 0.015 15.6 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 NTP_transferase PF00483.23 EMT53417.1 - 9.3e-52 176.1 0.0 1e-51 175.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EMT53417.1 - 1.3e-09 38.6 0.0 1.5e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4444 PF14563.6 EMT53417.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) Inos-1-P_synth PF01658.17 EMT53418.1 - 1.3e-30 105.8 0.0 2e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.12 EMT53418.1 - 2.8e-05 23.7 0.0 0.00015 21.3 0.0 1.9 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase YdjO PF14169.6 EMT53419.1 - 3.2e-26 90.8 7.6 3.5e-26 90.7 7.6 1.0 1 0 0 1 1 1 1 Cold-inducible protein YdjO DNA_ligase_ZBD PF03119.16 EMT53419.1 - 0.064 13.3 1.7 2.9 8.0 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Ogr_Delta PF04606.12 EMT53419.1 - 0.093 12.7 3.2 1 9.4 0.4 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger CobU PF02283.16 EMT53420.1 - 5.7e-54 182.2 0.0 6.7e-54 182.0 0.0 1.0 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase Erf4 PF10256.9 EMT53420.1 - 0.0089 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ABC_tran PF00005.27 EMT53421.1 - 1.9e-32 112.7 0.0 2.5e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT53421.1 - 1.8e-09 37.9 0.0 1e-05 25.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT53421.1 - 6.7e-08 32.2 0.1 0.0017 17.8 0.1 2.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMT53421.1 - 0.00015 21.4 0.1 0.00038 20.2 0.1 1.7 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT53421.1 - 0.0002 21.9 0.1 0.00032 21.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT53421.1 - 0.0016 18.9 0.0 0.0025 18.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT53421.1 - 0.0069 16.7 0.0 0.021 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMT53421.1 - 0.0081 15.9 0.4 0.029 14.1 0.4 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMT53421.1 - 0.0088 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMT53421.1 - 0.036 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EMT53421.1 - 0.064 13.8 0.0 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMT53421.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMT53421.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 EMT53421.1 - 0.16 12.1 0.0 0.82 9.8 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EMT53421.1 - 0.17 12.1 0.0 0.5 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain FecCD PF01032.18 EMT53422.1 - 1.6e-96 323.0 32.6 1.9e-96 322.8 32.6 1.0 1 0 0 1 1 1 1 FecCD transport family Peripla_BP_2 PF01497.18 EMT53423.1 - 2.5e-36 125.5 0.8 3e-36 125.2 0.8 1.1 1 0 0 1 1 1 1 Periplasmic binding protein EutC PF05985.11 EMT53424.1 - 6.7e-75 251.4 0.2 8.2e-75 251.1 0.2 1.1 1 0 0 1 1 1 1 Ethanolamine ammonia-lyase light chain (EutC) EutB PF06751.11 EMT53425.1 - 1e-196 654.0 0.0 1.1e-196 653.8 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia lyase large subunit (EutB) Dehydratase_LU PF02286.15 EMT53425.1 - 0.00034 19.3 0.2 0.05 12.2 0.1 2.1 2 0 0 2 2 2 2 Dehydratase large subunit ACP53EA PF06313.11 EMT53425.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Drosophila ACP53EA protein Response_reg PF00072.24 EMT53426.1 - 3.4e-29 101.3 0.2 3.9e-29 101.1 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CT_A_B PF02626.15 EMT53427.1 - 2e-78 263.7 0.0 2.3e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CT_C_D PF02682.16 EMT53428.1 - 1e-47 162.5 0.0 1.3e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Sigma54_activat PF00158.26 EMT53429.1 - 5.6e-70 234.4 0.0 9.4e-70 233.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT53429.1 - 1.1e-17 64.4 0.0 4.6e-17 62.4 0.0 2.1 2 1 0 2 2 2 1 Sigma-54 interaction domain PAS_9 PF13426.7 EMT53429.1 - 5.1e-09 36.3 0.3 0.004 17.4 0.1 3.2 2 0 0 2 2 2 2 PAS domain HTH_8 PF02954.19 EMT53429.1 - 2.1e-08 33.8 0.2 6e-08 32.3 0.2 1.9 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_50 PF18024.1 EMT53429.1 - 2.2e-08 33.5 0.2 1e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain AAA_5 PF07728.14 EMT53429.1 - 3.9e-07 30.1 0.0 9.3e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EMT53429.1 - 4e-07 30.5 0.1 2e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PAS PF00989.25 EMT53429.1 - 6.7e-07 29.3 0.1 4.2e-05 23.5 0.0 3.6 3 0 0 3 3 3 1 PAS fold Mg_chelatase PF01078.21 EMT53429.1 - 7.5e-06 25.5 0.0 0.00025 20.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PAS_8 PF13188.7 EMT53429.1 - 1e-05 25.4 0.0 5.4e-05 23.1 0.0 2.3 1 0 0 1 1 1 1 PAS domain AAA_2 PF07724.14 EMT53429.1 - 0.0019 18.3 0.1 0.0078 16.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) PAS_4 PF08448.10 EMT53429.1 - 0.002 18.4 0.0 0.6 10.4 0.0 3.4 3 1 0 3 3 3 1 PAS fold RsgA_GTPase PF03193.16 EMT53429.1 - 0.0053 16.7 0.3 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase HTH_24 PF13412.6 EMT53429.1 - 0.01 15.3 0.1 0.031 13.8 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EMT53429.1 - 0.023 14.5 0.9 0.045 13.6 0.1 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PAS_7 PF12860.7 EMT53429.1 - 0.034 14.3 0.2 0.36 11.0 0.0 2.8 2 1 1 3 3 3 0 PAS fold HTH_1 PF00126.27 EMT53429.1 - 0.051 13.5 0.2 0.15 12.0 0.2 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 EMT53429.1 - 0.067 13.1 0.1 0.21 11.5 0.1 1.9 1 1 0 1 1 1 0 MarR family AAA_3 PF07726.11 EMT53429.1 - 0.076 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HTH_38 PF13936.6 EMT53429.1 - 0.083 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 EMT53429.1 - 0.1 12.4 0.2 0.46 10.3 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Fe_dep_repress PF01325.19 EMT53429.1 - 0.11 12.7 0.1 0.41 10.9 0.1 2.0 2 0 0 2 2 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_28 PF13518.6 EMT53429.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_16 PF13191.6 EMT53429.1 - 0.13 12.6 0.0 0.42 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain HTH_Tnp_ISL3 PF13542.6 EMT53429.1 - 0.15 11.5 0.0 0.39 10.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ZapB PF06005.12 EMT53429.1 - 9.4 6.8 12.1 1.7 9.2 2.5 3.8 3 1 0 3 3 3 0 Cell division protein ZapB LamB_YcsF PF03746.16 EMT53430.1 - 7.1e-97 323.8 0.1 8e-97 323.6 0.1 1.0 1 0 0 1 1 1 1 LamB/YcsF family ESP PF16590.5 EMT53430.1 - 0.16 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Exocrine gland-secreting peptide Biotin_lipoyl PF00364.22 EMT53431.1 - 1.5e-10 40.7 0.3 1.7e-10 40.6 0.3 1.0 1 0 0 1 1 1 1 Biotin-requiring enzyme CT_A_B PF02626.15 EMT53432.1 - 3.6e-87 292.4 0.1 4.1e-87 292.2 0.1 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CT_C_D PF02682.16 EMT53433.1 - 1.2e-45 155.7 0.0 1.6e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D YdiH PF15930.5 EMT53433.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function HPPK PF01288.20 EMT53433.1 - 0.17 12.4 0.1 0.29 11.6 0.1 1.4 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NTP_transf_3 PF12804.7 EMT53434.1 - 1.5e-27 96.9 0.0 1.8e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EMT53434.1 - 2.2e-05 24.3 0.0 0.00015 21.6 0.0 1.9 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 EMT53434.1 - 0.1 12.5 0.0 1.3 8.9 0.0 2.4 3 0 0 3 3 3 0 Cytidylyltransferase XdhC_C PF13478.6 EMT53435.1 - 3.9e-35 121.1 0.0 6.2e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 EMT53435.1 - 1.1e-27 96.0 1.9 1.7e-21 76.1 1.2 2.6 2 0 0 2 2 2 2 XdhC and CoxI family VWA_CoxE PF05762.14 EMT53436.1 - 8.8e-47 159.4 2.5 2.8e-22 79.2 0.0 2.3 1 1 1 2 2 2 2 VWA domain containing CoxE-like protein AAA_5 PF07728.14 EMT53437.1 - 3.6e-13 49.7 0.1 6.7e-13 48.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EMT53437.1 - 4.1e-10 40.2 0.0 1.1e-09 38.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 EMT53437.1 - 2.9e-09 36.9 0.0 0.00046 20.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT53437.1 - 4.4e-08 33.7 1.0 8.9e-08 32.7 0.2 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMT53437.1 - 2e-06 28.1 0.1 9.2e-06 26.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EMT53437.1 - 3.6e-05 23.5 0.2 0.03 14.1 0.1 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EMT53437.1 - 4.4e-05 23.6 0.0 6.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_6 PF12774.7 EMT53437.1 - 0.00012 21.1 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region ATPase_2 PF01637.18 EMT53437.1 - 0.0023 17.9 0.0 0.0041 17.1 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EMT53437.1 - 0.0035 17.9 0.0 0.014 15.9 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 EMT53437.1 - 0.0045 17.0 0.1 0.054 13.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EMT53437.1 - 0.0096 15.6 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EMT53437.1 - 0.016 14.6 0.1 0.039 13.3 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EMT53437.1 - 0.017 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EMT53437.1 - 0.026 14.9 0.0 0.09 13.2 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EMT53437.1 - 0.026 14.8 0.1 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Med8 PF10232.9 EMT53437.1 - 0.031 13.9 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 AAA_30 PF13604.6 EMT53437.1 - 0.032 14.0 0.1 0.12 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EMT53437.1 - 0.039 13.9 0.9 0.3 11.0 0.9 2.2 1 1 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 EMT53437.1 - 0.11 12.4 0.0 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 NTPase KAP_NTPase PF07693.14 EMT53437.1 - 0.14 11.4 0.1 1.7 7.8 0.1 2.0 2 0 0 2 2 2 0 KAP family P-loop domain AAA_24 PF13479.6 EMT53437.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain FAD_binding_5 PF00941.21 EMT53438.1 - 1e-46 158.8 0.0 1.4e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EMT53438.1 - 2.6e-19 69.3 0.0 5.1e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain FAD_binding_4 PF01565.23 EMT53438.1 - 0.00071 19.3 0.1 0.0035 17.1 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Ald_Xan_dh_C2 PF02738.18 EMT53439.1 - 9.3e-190 631.7 1.6 1.1e-189 631.5 1.6 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 EMT53439.1 - 2.1e-30 105.3 0.0 2.1e-30 105.3 0.0 1.9 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SHMT PF00464.19 EMT53439.1 - 0.015 14.0 0.0 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Serine hydroxymethyltransferase Fer2_2 PF01799.20 EMT53440.1 - 2.6e-32 110.7 1.4 1.2e-30 105.4 0.1 2.2 2 0 0 2 2 2 2 [2Fe-2S] binding domain Fer2 PF00111.27 EMT53440.1 - 2.5e-06 27.4 0.9 2.5e-06 27.4 0.9 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 EMT53440.1 - 0.0003 20.8 0.3 0.0005 20.1 0.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF2946 PF11162.8 EMT53440.1 - 0.01 16.5 3.1 0.045 14.4 3.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) COXG PF06240.13 EMT53441.1 - 6.7e-24 84.2 0.1 7.8e-24 84.0 0.1 1.0 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) DUF2505 PF10698.9 EMT53441.1 - 0.0001 22.5 0.4 0.044 13.9 0.4 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2505) Polyketide_cyc PF03364.20 EMT53441.1 - 0.00047 20.4 0.0 0.00092 19.4 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 EMT53441.1 - 0.059 13.6 0.0 0.097 12.9 0.0 1.4 1 1 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein MaoC_dehydratas PF01575.19 EMT53442.1 - 1.4e-18 66.7 0.0 1.6e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EMT53442.1 - 0.0021 18.2 0.0 0.0038 17.3 0.0 1.6 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase MaoC_dehydrat_N PF13452.6 EMT53443.1 - 6.3e-25 87.8 0.0 1e-24 87.1 0.0 1.3 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase Response_reg PF00072.24 EMT53444.1 - 2.6e-33 114.6 0.0 3.6e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT53444.1 - 7.6e-27 93.2 0.4 1.5e-26 92.3 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Cu-oxidase_3 PF07732.15 EMT53445.1 - 2.7e-45 153.2 5.4 1.7e-33 115.1 0.4 3.8 3 1 1 4 4 4 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMT53445.1 - 3.4e-43 146.7 1.4 3.7e-29 101.2 0.8 4.2 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 EMT53445.1 - 1.4e-19 70.8 0.1 2.1e-08 34.4 0.0 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EMT53445.1 - 1.6e-13 50.6 0.0 1.8e-05 24.8 0.0 3.9 3 1 1 4 4 4 3 Cupredoxin-like domain SH3_2 PF07653.17 EMT53445.1 - 0.0027 17.3 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain CusF_Ec PF11604.8 EMT53445.1 - 0.011 15.7 3.8 10 6.1 0.1 4.6 4 1 1 5 5 5 0 Copper binding periplasmic protein CusF DUF5060 PF16586.5 EMT53445.1 - 0.034 14.5 0.1 1.9 8.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5060) CT_A_B PF02626.15 EMT53445.1 - 0.049 13.3 0.1 11 5.5 0.0 3.3 3 1 0 3 3 3 0 Carboxyltransferase domain, subdomain A and B Fn3_assoc PF13287.6 EMT53445.1 - 0.14 12.3 0.1 0.54 10.4 0.1 2.0 1 0 0 1 1 1 0 Fn3 associated Pentapeptide_2 PF01469.18 EMT53445.1 - 4.3 7.3 5.7 1.1e+02 2.8 5.7 2.6 1 1 0 1 1 1 0 Pentapeptide repeats (8 copies) SNARE_assoc PF09335.11 EMT53446.1 - 1.5e-20 73.9 5.4 1.5e-20 73.9 5.4 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4212 PF13937.6 EMT53446.1 - 0.25 11.7 13.3 2 8.9 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) DUF2294 PF10057.9 EMT53447.1 - 1.8e-31 108.5 0.5 2e-31 108.4 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2294) EstA_Ig_like PF18435.1 EMT53447.1 - 0.049 13.8 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain DUF1641 PF07849.11 EMT53448.1 - 1.8e-14 53.3 0.7 4.4e-14 52.1 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1641) Sec3_C_2 PF15278.6 EMT53448.1 - 0.0084 16.4 0.1 0.023 15.0 0.0 1.7 2 0 0 2 2 2 1 Sec3 exocyst complex subunit GAPES3 PF17154.4 EMT53448.1 - 0.034 14.1 0.2 0.076 13.0 0.2 1.6 1 1 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Molybdopterin PF00384.22 EMT53449.1 - 2.5e-79 267.3 0.0 3.4e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EMT53449.1 - 2.2e-21 76.0 0.1 4.7e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 EMT53449.1 - 3.5e-19 68.5 0.5 1e-18 67.0 0.5 1.9 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2_4 PF13510.6 EMT53449.1 - 1.5e-13 50.6 0.2 1.5e-13 50.6 0.2 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 EMT53449.1 - 4.2e-10 39.0 19.5 6.5e-06 25.8 3.7 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain NADH-G_4Fe-4S_3 PF10588.9 EMT53449.1 - 7.5e-09 35.0 4.2 7.5e-09 35.0 4.2 2.4 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer4_6 PF12837.7 EMT53449.1 - 1.9e-08 34.0 17.3 0.00031 20.7 5.4 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EMT53449.1 - 2.4e-06 27.6 10.1 2.4e-06 27.6 10.1 2.9 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EMT53449.1 - 3.6e-06 27.5 12.5 3.6e-06 27.5 12.5 4.2 3 1 2 5 5 4 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMT53449.1 - 1e-05 25.5 8.6 0.00034 20.7 3.4 3.7 3 1 0 3 3 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EMT53449.1 - 2.7e-05 24.2 14.1 2.7e-05 24.2 14.1 3.9 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EMT53449.1 - 0.00028 21.3 10.1 0.00028 21.3 10.1 3.4 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EMT53449.1 - 0.0012 19.4 11.1 0.0012 19.4 11.1 3.5 3 1 2 5 5 4 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EMT53449.1 - 0.0048 16.9 12.2 0.0076 16.3 2.6 3.5 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 EMT53449.1 - 0.0067 17.1 6.8 0.91 10.3 0.8 2.7 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_16 PF13484.6 EMT53449.1 - 0.1 13.6 24.6 0.12 13.3 6.9 4.3 4 2 0 4 4 3 0 4Fe-4S double cluster binding domain Fer4_13 PF13370.6 EMT53449.1 - 0.5 11.0 16.4 5.3 7.7 1.7 3.5 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 EMT53449.1 - 7.5 7.3 23.7 0.043 14.3 2.7 3.2 3 0 0 3 3 2 0 4Fe-4S binding domain HIT PF01230.23 EMT53450.1 - 2.2e-26 92.4 1.7 2.5e-26 92.3 1.7 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EMT53450.1 - 6.5e-26 91.1 0.7 7.6e-26 90.8 0.7 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HTH_37 PF13744.6 EMT53450.1 - 0.083 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain CwfJ_C_1 PF04677.15 EMT53450.1 - 0.095 12.6 0.5 0.13 12.1 0.5 1.3 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Pyr_redox_3 PF13738.6 EMT53451.1 - 1.2e-85 287.5 0.0 1.4e-85 287.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMT53451.1 - 1.3e-33 116.6 0.0 1.6e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMT53451.1 - 7e-12 45.7 1.7 1.4e-08 35.2 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMT53451.1 - 6.4e-11 42.1 2.6 2e-07 30.6 0.2 2.6 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 EMT53451.1 - 4.8e-08 32.1 1.2 0.0011 17.8 0.1 3.7 4 0 0 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 EMT53451.1 - 7.4e-08 32.5 0.1 5.4e-05 23.3 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EMT53451.1 - 8.8e-08 31.7 0.3 3.3e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EMT53451.1 - 3.2e-06 26.5 2.0 6.7e-05 22.1 0.1 2.9 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 EMT53451.1 - 4.8e-06 26.9 0.1 0.002 18.5 0.1 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 EMT53451.1 - 5.1e-06 26.3 3.6 0.0049 16.5 0.1 3.8 3 1 1 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 EMT53451.1 - 5.2e-06 25.8 0.1 0.058 12.5 0.0 3.7 4 0 0 4 4 4 2 Glucose inhibited division protein A Thi4 PF01946.17 EMT53451.1 - 8.6e-06 25.2 1.0 0.01 15.1 0.1 2.5 3 0 0 3 3 3 2 Thi4 family FAD_oxidored PF12831.7 EMT53451.1 - 0.0001 21.8 7.1 0.011 15.2 0.2 3.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase ApbA PF02558.16 EMT53451.1 - 0.00074 19.2 0.4 1.2 8.8 0.0 2.9 3 0 0 3 3 3 2 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EMT53451.1 - 0.014 15.7 0.1 5.6 7.3 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.12 EMT53451.1 - 0.017 14.2 0.3 0.087 11.9 0.0 2.2 2 1 1 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EMT53451.1 - 0.024 13.9 2.3 1.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 EMT53451.1 - 0.025 13.0 0.1 0.22 9.9 0.1 2.0 1 1 0 1 1 1 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 EMT53451.1 - 0.034 14.2 0.0 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EMT53451.1 - 0.041 13.9 0.6 3.1 7.8 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Glyco_transf_4 PF13439.6 EMT53451.1 - 0.11 12.4 0.0 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 IlvN PF07991.12 EMT53451.1 - 0.13 11.8 0.2 15 5.1 0.0 2.4 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Amino_oxidase PF01593.24 EMT53451.1 - 0.4 9.9 2.6 0.63 9.3 0.0 2.6 5 0 0 5 5 5 0 Flavin containing amine oxidoreductase SLH PF00395.20 EMT53452.1 - 1.5e-37 127.3 0.7 1.3e-12 47.5 0.0 3.7 3 0 0 3 3 3 3 S-layer homology domain Glyco_hydro_18 PF00704.28 EMT53452.1 - 2.4e-26 93.2 3.3 6.9e-26 91.7 2.1 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EMT53452.1 - 0.00017 21.2 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Epimerase PF01370.21 EMT53453.1 - 1.6e-26 93.3 0.0 1.9e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMT53453.1 - 4.1e-21 75.7 0.0 2.2e-20 73.3 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EMT53453.1 - 5.7e-13 48.6 0.0 8e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EMT53453.1 - 1.2e-07 31.2 0.0 5e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EMT53453.1 - 4.3e-05 22.7 0.0 5.8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMT53453.1 - 0.0033 16.6 0.0 0.011 14.9 0.0 1.9 2 1 0 2 2 2 1 Male sterility protein KR PF08659.10 EMT53453.1 - 0.0075 16.2 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 EMT53453.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Aminotran_1_2 PF00155.21 EMT53454.1 - 2.4e-66 224.4 0.0 2.8e-66 224.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMT53454.1 - 3.4e-06 25.8 0.1 5e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EMT53454.1 - 0.0093 15.3 1.3 0.02 14.2 1.3 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 EMT53454.1 - 0.041 12.6 0.3 0.19 10.4 0.3 1.9 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain 2Fe-2S_thioredx PF01257.19 EMT53455.1 - 3.8e-07 30.1 0.2 4.8e-07 29.7 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Suc_Fer-like PF06999.12 EMT53455.1 - 0.038 13.9 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Sucrase/ferredoxin-like HATPase_c PF02518.26 EMT53456.1 - 9.4e-28 97.0 0.0 1.8e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 EMT53456.1 - 8.3e-11 42.1 0.0 2.1e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 EMT53456.1 - 8.1e-09 35.4 1.2 2.6e-08 33.8 0.5 2.3 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EMT53456.1 - 8.3e-05 22.5 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EMT53456.1 - 0.00013 21.8 0.0 0.00036 20.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EMT53456.1 - 0.00022 21.1 0.0 0.00061 19.7 0.0 1.7 1 0 0 1 1 1 1 GHKL domain DUF2244 PF10003.9 EMT53456.1 - 0.13 11.9 1.5 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) HTH_3 PF01381.22 EMT53457.1 - 1.3e-14 54.0 0.1 1.4e-14 53.8 0.1 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EMT53457.1 - 4e-07 30.0 0.0 4.5e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EMT53457.1 - 1.1e-06 28.9 0.0 1.4e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EMT53457.1 - 4.5e-05 23.2 0.0 6.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EMT53457.1 - 0.00013 22.3 0.0 0.00014 22.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 EMT53457.1 - 0.027 14.4 0.1 0.078 12.9 0.1 1.7 2 0 0 2 2 2 0 HTH domain HTH_28 PF13518.6 EMT53457.1 - 0.087 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3796 PF12676.7 EMT53458.1 - 0.0075 16.7 5.7 0.012 16.0 5.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3796) FA_desaturase PF00487.24 EMT53458.1 - 0.018 14.9 5.7 0.02 14.7 5.7 1.0 1 0 0 1 1 1 0 Fatty acid desaturase DUF2207 PF09972.9 EMT53458.1 - 0.16 10.7 2.8 0.16 10.7 2.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sec62 PF03839.16 EMT53458.1 - 3.3 7.2 5.8 4.2 6.8 5.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4111 PF13427.6 EMT53459.1 - 1.5e-09 37.9 0.2 2.2e-09 37.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) NTP_transf_2 PF01909.23 EMT53459.1 - 3.1e-06 27.4 0.0 6.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EMT53459.1 - 2e-05 24.6 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Adenyl_cycl_N PF12633.7 EMT53459.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 2 0 0 2 2 2 0 Adenylate cyclase NT domain Phage_integrase PF00589.22 EMT53461.1 - 3.4e-28 98.6 0.2 6.2e-28 97.7 0.2 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 EMT53461.1 - 5.7e-06 26.7 4.2 0.097 13.2 0.0 3.6 3 1 0 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 EMT53461.1 - 6.7e-06 26.4 0.4 0.0047 17.2 0.3 3.4 2 1 0 2 2 2 1 Phage integrase SAM-like domain Phage_int_SAM_1 PF02899.17 EMT53461.1 - 1e-05 25.7 1.0 0.027 14.7 1.0 3.0 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain IES5 PF17335.2 EMT53461.1 - 0.02 15.2 0.7 0.75 10.1 0.2 2.7 2 1 0 2 2 2 0 Ino80 complex subunit 5 Transgly PF00912.22 EMT53462.1 - 9e-65 217.4 0.1 1.1e-64 217.2 0.1 1.1 1 0 0 1 1 1 1 Transglycosylase AMP-binding PF00501.28 EMT53463.1 - 8.8e-89 298.0 0.0 1.1e-88 297.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMT53463.1 - 7.7e-25 87.7 1.5 1.7e-24 86.6 1.5 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4131 PF13567.6 EMT53464.1 - 1.2 8.7 15.9 0.55 9.9 0.8 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) AhpC-TSA PF00578.21 EMT53465.1 - 7.2e-28 97.0 0.0 8.9e-28 96.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMT53465.1 - 3.4e-27 94.9 0.0 4.7e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EMT53465.1 - 1.8e-16 60.2 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 EMT53465.1 - 1.9e-11 43.9 0.1 5.8e-09 35.9 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EMT53465.1 - 2.3e-10 40.9 0.0 3.1e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EMT53465.1 - 1.7e-06 28.1 0.1 2.4e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like SCO1-SenC PF02630.14 EMT53465.1 - 0.00043 20.2 0.0 0.00073 19.5 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC TraF PF13728.6 EMT53465.1 - 0.0022 17.9 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein YtfJ_HI0045 PF09695.10 EMT53465.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) T4_deiodinase PF00837.17 EMT53465.1 - 0.035 13.4 0.0 0.064 12.5 0.0 1.5 1 1 1 2 2 2 0 Iodothyronine deiodinase zf_C2H2_10 PF18414.1 EMT53465.1 - 0.062 12.8 0.3 0.43 10.2 0.3 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger GSHPx PF00255.19 EMT53465.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 Glutathione peroxidase NLPC_P60 PF00877.19 EMT53466.1 - 5.9e-44 148.4 1.0 2.4e-26 91.8 0.1 2.1 2 0 0 2 2 2 2 NlpC/P60 family Peptidase_C92 PF05708.12 EMT53466.1 - 3.2e-06 27.4 0.9 0.0061 16.7 0.1 3.2 3 1 0 3 3 3 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Amidase_5 PF05382.13 EMT53466.1 - 2.6e-05 24.1 1.7 0.19 11.6 0.2 2.7 2 2 0 2 2 2 2 Bacteriophage peptidoglycan hydrolase CHAP PF05257.16 EMT53466.1 - 0.00031 21.3 0.0 0.37 11.4 0.0 2.5 2 0 0 2 2 2 2 CHAP domain DUF1175 PF06672.11 EMT53466.1 - 0.0031 17.2 0.0 0.33 10.6 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1175) LRAT PF04970.13 EMT53466.1 - 0.044 14.1 0.1 3.5 7.9 0.0 2.6 2 1 0 2 2 2 0 Lecithin retinol acyltransferase UN_NPL4 PF11543.8 EMT53466.1 - 0.073 13.6 0.0 1.5 9.4 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 EVE PF01878.18 EMT53466.1 - 0.11 12.5 0.1 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 EVE domain FAA_hydrolase PF01557.18 EMT53467.1 - 2.1e-33 115.8 0.0 2.5e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family VanW PF04294.13 EMT53469.1 - 2e-48 163.4 0.1 2.3e-48 163.2 0.1 1.0 1 0 0 1 1 1 1 VanW like protein DSBA PF01323.20 EMT53470.1 - 3.8e-35 121.4 0.0 4.4e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EMT53470.1 - 1.2e-07 32.1 0.0 3.4e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMT53470.1 - 9.1e-05 22.9 0.0 0.0028 18.1 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EMT53470.1 - 0.0003 20.8 0.0 0.0097 15.9 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain ABC2_membrane_4 PF12730.7 EMT53471.1 - 6.5e-23 81.6 10.7 6.5e-23 81.6 10.7 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein TRM13 PF05206.14 EMT53471.1 - 0.25 10.8 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 ABC2_membrane_4 PF12730.7 EMT53472.1 - 6.7e-21 75.0 9.1 8.9e-21 74.6 9.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EMT53472.1 - 6.2e-05 22.4 18.1 0.0013 18.0 18.1 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 EMT53472.1 - 0.087 11.9 20.6 0.021 13.9 15.1 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF2673 PF10880.8 EMT53472.1 - 0.17 12.0 1.3 0.24 11.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) ABC2_membrane_5 PF13346.6 EMT53472.1 - 0.19 11.3 14.4 5 6.6 14.4 2.4 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3671 PF12420.8 EMT53472.1 - 0.26 11.4 3.1 5.5 7.1 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function ABC_tran PF00005.27 EMT53473.1 - 6.9e-28 97.9 0.0 2.2e-27 96.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EMT53473.1 - 2.9e-13 50.3 1.1 2.1e-08 34.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMT53473.1 - 0.0032 17.7 0.0 0.013 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF4162 PF13732.6 EMT53473.1 - 0.012 16.3 0.2 0.027 15.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) AAA_29 PF13555.6 EMT53473.1 - 0.028 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT53473.1 - 0.049 14.1 0.3 0.1 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMT53473.1 - 0.063 13.7 0.1 0.2 12.0 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EMT53473.1 - 0.074 12.8 0.4 0.18 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 EMT53473.1 - 0.27 10.8 1.0 5.9 6.4 0.1 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Response_reg PF00072.24 EMT53474.1 - 1.5e-25 89.5 0.0 2.1e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT53474.1 - 1.4e-23 82.7 0.0 2.4e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 EMT53475.1 - 2.9e-17 63.2 0.0 5e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT53475.1 - 2.6e-13 49.8 0.1 7.1e-13 48.4 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EMT53475.1 - 4e-06 26.7 0.0 7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT53475.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 EMT53475.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 GHKL domain APH PF01636.23 EMT53476.1 - 1.6e-22 80.6 0.1 2e-22 80.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMT53476.1 - 3.3e-09 36.6 0.1 5.6e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EMT53476.1 - 1e-05 25.1 0.2 1.7e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase RIO1 PF01163.22 EMT53476.1 - 0.006 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family DUF4135 PF13575.6 EMT53476.1 - 0.084 12.2 0.1 0.31 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) DUF4404 PF14357.6 EMT53476.1 - 0.29 11.8 2.0 0.76 10.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Pyr_redox_2 PF07992.14 EMT53478.1 - 2.7e-27 95.8 0.0 2.3e-26 92.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT53478.1 - 4.9e-08 32.6 0.1 0.0058 15.9 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMT53478.1 - 2.4e-07 30.2 0.2 4.2e-05 22.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EMT53478.1 - 1.9e-06 26.9 0.2 6.8e-05 21.7 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EMT53478.1 - 2.3e-06 26.9 0.1 0.01 14.9 0.1 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.22 EMT53478.1 - 3.1e-06 26.6 0.5 0.013 14.6 0.3 3.1 2 1 1 3 3 3 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EMT53478.1 - 2e-05 24.6 0.1 0.11 12.4 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 EMT53478.1 - 6.7e-05 22.6 0.1 0.00015 21.5 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMT53478.1 - 0.00012 21.5 0.1 0.00019 20.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMT53478.1 - 0.0021 18.3 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EMT53478.1 - 0.003 16.9 4.0 0.026 13.8 0.2 2.5 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EMT53478.1 - 0.0036 16.6 0.3 0.0096 15.2 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EMT53478.1 - 0.0057 16.1 0.4 0.0091 15.4 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMT53478.1 - 0.02 15.4 0.0 0.11 13.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMT53478.1 - 0.07 12.0 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NLPC_P60 PF00877.19 EMT53479.1 - 1.8e-26 92.2 0.0 3.1e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family LysM PF01476.20 EMT53479.1 - 7.5e-13 48.3 0.0 1.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 LysM domain SH3_3 PF08239.11 EMT53479.1 - 1.9e-11 44.0 0.0 1.7e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Bacterial SH3 domain DUF1175 PF06672.11 EMT53479.1 - 0.00021 21.1 0.1 0.001 18.8 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1175) SH3_4 PF06347.13 EMT53479.1 - 0.00044 20.0 0.0 0.00087 19.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain OapA PF04225.12 EMT53479.1 - 0.009 16.1 0.1 0.035 14.2 0.1 1.9 2 0 0 2 2 2 1 Opacity-associated protein A LysM-like domain CHAP PF05257.16 EMT53479.1 - 0.016 15.8 0.0 0.041 14.4 0.0 1.6 1 0 0 1 1 1 0 CHAP domain LRAT PF04970.13 EMT53479.1 - 0.019 15.3 0.1 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 Lecithin retinol acyltransferase Gp45_2 PF17470.2 EMT53479.1 - 0.034 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Phage gene product 45.2 HRDC PF00570.23 EMT53479.1 - 0.089 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 HRDC domain LysE PF01810.18 EMT53480.1 - 1.9e-14 53.6 12.1 2.2e-14 53.4 12.1 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 EMT53480.1 - 0.083 12.6 11.6 1.9 8.1 11.6 2.3 1 1 0 1 1 1 0 Integral membrane protein TerC family DUF92 PF01940.16 EMT53480.1 - 0.083 12.3 2.6 0.12 11.8 2.5 1.8 1 1 0 1 1 1 0 Integral membrane protein DUF92 HTH_3 PF01381.22 EMT53481.1 - 7.3e-16 58.0 0.2 1e-15 57.5 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix Cupin_2 PF07883.11 EMT53481.1 - 4.6e-15 55.1 0.0 7.9e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain HTH_19 PF12844.7 EMT53481.1 - 2.6e-08 33.8 0.0 4.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EMT53481.1 - 1.1e-07 32.0 0.0 1.8e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 EMT53481.1 - 2.1e-05 24.3 0.0 3.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_3 PF05899.12 EMT53481.1 - 0.0056 16.4 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 EMT53481.1 - 0.0081 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 EMT53481.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Sigma70_r4 PF04545.16 EMT53481.1 - 0.057 13.0 0.2 0.16 11.5 0.2 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 LysM PF01476.20 EMT53481.1 - 0.13 12.3 0.4 15 5.7 0.0 2.4 2 0 0 2 2 2 0 LysM domain UDPG_MGDP_dh_N PF03721.14 EMT53482.1 - 7.8e-42 143.0 0.0 1.2e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EMT53482.1 - 3.2e-30 104.2 0.0 5.4e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EMT53482.1 - 2.7e-20 72.8 0.0 1.1e-19 70.8 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 EMT53482.1 - 4.2e-08 33.5 0.0 3.7e-07 30.5 0.0 2.4 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EMT53482.1 - 0.0017 18.3 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EMT53482.1 - 0.0075 15.6 0.1 0.14 11.5 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMT53482.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 EMT53482.1 - 0.059 12.7 0.1 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 ThiF family Rossmann-like PF10727.9 EMT53482.1 - 0.079 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_11 PF14833.6 EMT53482.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CBM39 PF15886.5 EMT53482.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) Response_reg PF00072.24 EMT53483.1 - 6.5e-22 77.8 0.0 1.3e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Glyco_tranf_2_3 PF13641.6 EMT53484.1 - 1e-25 91.0 0.0 1.3e-24 87.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EMT53484.1 - 8.5e-20 71.2 0.3 1.2e-18 67.5 0.3 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EMT53484.1 - 5e-13 49.4 0.2 1.3e-12 48.1 0.2 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.15 EMT53484.1 - 2e-12 46.5 0.2 1.1e-08 34.1 0.0 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_tranf_2_2 PF10111.9 EMT53484.1 - 2.5e-06 27.2 0.4 0.036 13.6 0.1 3.1 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EMT53484.1 - 0.015 14.7 0.0 3.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 EMT53484.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 HEAT_2 PF13646.6 EMT53485.1 - 1.2e-15 57.6 9.5 1.5e-09 38.1 0.7 3.7 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 EMT53485.1 - 6.4e-09 35.3 5.8 0.073 13.4 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.16 EMT53485.1 - 0.00084 19.8 5.9 0.66 10.8 0.0 4.8 5 0 0 5 5 5 2 PBS lyase HEAT-like repeat Cnd1 PF12717.7 EMT53485.1 - 0.0079 16.2 0.1 1.7 8.7 0.1 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TPR_20 PF14561.6 EMT53485.1 - 0.13 12.6 1.4 4.1 7.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel_put PF04328.13 EMT53486.1 - 0.028 14.4 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 Selenoprotein, putative Peptidase_M3 PF01432.20 EMT53488.1 - 4e-28 98.9 2.4 1.1e-27 97.5 2.4 1.7 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 EMT53488.1 - 6.8e-10 39.1 0.8 6.8e-10 39.1 0.8 3.1 4 0 0 4 4 4 1 Oligopeptidase F Reprolysin_3 PF13582.6 EMT53488.1 - 0.3 11.6 1.4 0.66 10.5 0.3 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Strep_SA_rep PF06696.11 EMT53488.1 - 1.4 9.0 8.3 0.39 10.8 2.1 3.0 2 0 0 2 2 2 0 Streptococcal surface antigen repeat TMF_DNA_bd PF12329.8 EMT53488.1 - 2.5 8.1 9.4 24 5.0 3.2 3.8 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Peptidase_M20 PF01546.28 EMT53489.1 - 3.3e-34 118.4 0.0 4.7e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT53489.1 - 1.3e-20 73.3 0.0 2.2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain SIMPL PF04402.14 EMT53489.1 - 0.076 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Peptidase_M28 PF04389.17 EMT53489.1 - 0.11 12.2 0.0 8.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M28 Peptidase_S58 PF03576.14 EMT53490.1 - 2.8e-60 204.4 8.4 3.6e-60 204.0 8.4 1.0 1 0 0 1 1 1 1 Peptidase family S58 ECF_trnsprt PF12822.7 EMT53491.1 - 1.6e-23 83.7 28.7 1.9e-23 83.4 28.7 1.0 1 0 0 1 1 1 1 ECF transporter, substrate-specific component Romo1 PF10247.9 EMT53491.1 - 0.036 14.4 6.7 0.044 14.2 0.6 2.5 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 XK-related PF09815.9 EMT53491.1 - 0.23 10.5 3.5 0.32 10.0 3.5 1.3 1 0 0 1 1 1 0 XK-related protein NCE101 PF11654.8 EMT53491.1 - 0.27 10.9 2.0 1.6 8.5 0.1 2.6 2 0 0 2 2 2 0 Non-classical export protein 1 CbiQ PF02361.16 EMT53492.1 - 2.6e-33 115.5 10.4 4e-33 114.9 10.4 1.3 1 0 0 1 1 1 1 Cobalt transport protein ABC_tran PF00005.27 EMT53493.1 - 9.4e-32 110.4 0.0 1.4e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT53493.1 - 5.7e-15 55.9 0.3 1.4e-10 41.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT53493.1 - 1.5e-09 37.6 0.0 2.9e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain TniB PF05621.11 EMT53493.1 - 2.7e-06 26.9 0.1 0.038 13.4 0.0 2.2 2 0 0 2 2 2 2 Bacterial TniB protein AAA_29 PF13555.6 EMT53493.1 - 6.4e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT53493.1 - 9.1e-06 26.0 0.0 8.6e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT53493.1 - 5.8e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 EMT53493.1 - 0.00038 20.3 0.0 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMT53493.1 - 0.0017 18.3 0.0 0.0057 16.6 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EMT53493.1 - 0.0025 18.3 0.0 0.0037 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 EMT53493.1 - 0.017 15.2 0.0 0.057 13.5 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 EMT53493.1 - 0.018 14.7 0.1 0.055 13.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 EMT53493.1 - 0.019 15.2 0.0 0.17 12.1 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 EMT53493.1 - 0.019 14.7 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase PF06745.13 EMT53493.1 - 0.02 14.2 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 KaiC MMR_HSR1 PF01926.23 EMT53493.1 - 0.029 14.5 0.1 0.085 12.9 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EMT53493.1 - 0.037 13.3 0.0 0.099 11.9 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EMT53493.1 - 0.051 13.3 0.1 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMT53493.1 - 0.11 12.1 0.0 1.3 8.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 EMT53493.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 EMT53493.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 EMT53493.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 EMT53493.1 - 0.13 12.0 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EMT53493.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EMT53493.1 - 0.16 12.1 0.0 0.51 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF1192 PF06698.11 EMT53493.1 - 0.16 12.0 0.2 13 5.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) ABC_tran PF00005.27 EMT53494.1 - 3e-32 112.0 0.0 4.9e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT53494.1 - 4.1e-11 42.7 0.9 1e-09 38.2 0.5 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EMT53494.1 - 0.00014 22.4 0.1 0.46 11.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EMT53494.1 - 0.00037 20.2 0.0 0.00075 19.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EMT53494.1 - 0.00093 19.1 0.2 0.065 13.0 0.1 2.4 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EMT53494.1 - 0.0013 18.5 0.1 0.016 15.0 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.6 EMT53494.1 - 0.006 17.1 0.0 0.008 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMT53494.1 - 0.012 15.4 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 EMT53494.1 - 0.013 15.2 0.0 3.5 7.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein TniB PF05621.11 EMT53494.1 - 0.017 14.6 0.1 0.49 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 EMT53494.1 - 0.024 15.0 0.0 0.032 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EMT53494.1 - 0.032 14.5 0.1 0.35 11.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain KdpD PF02702.17 EMT53494.1 - 0.033 13.7 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain RsgA_GTPase PF03193.16 EMT53494.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 EMT53494.1 - 0.13 11.9 0.2 0.96 9.1 0.2 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain KTI12 PF08433.10 EMT53494.1 - 0.19 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 adh_short_C2 PF13561.6 EMT53495.1 - 5.7e-65 219.1 0.3 7.3e-65 218.8 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT53495.1 - 7.7e-57 191.9 0.4 1e-56 191.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT53495.1 - 5.3e-06 26.5 1.1 1.9e-05 24.7 1.1 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMT53495.1 - 0.00073 19.1 0.1 0.002 17.7 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EMT53495.1 - 0.013 14.8 0.3 0.98 8.7 0.0 2.5 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EMT53495.1 - 0.017 15.0 0.2 0.024 14.5 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EMT53495.1 - 0.027 13.6 0.1 0.038 13.1 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.15 EMT53495.1 - 0.051 13.4 0.2 0.081 12.8 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF1776 PF08643.10 EMT53495.1 - 0.083 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF1100 PF06500.11 EMT53495.1 - 0.24 10.2 0.0 0.34 9.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Aldedh PF00171.22 EMT53496.1 - 3.9e-154 513.6 0.2 4.4e-154 513.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EMT53496.1 - 0.066 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Iso_dh PF00180.20 EMT53497.1 - 1.4e-87 294.1 0.0 1.6e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sigma54_activat PF00158.26 EMT53498.1 - 5.7e-67 224.6 0.0 8.2e-67 224.1 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT53498.1 - 8.9e-17 61.5 0.0 3.1e-16 59.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 EMT53498.1 - 6.6e-15 54.6 2.7 1.3e-14 53.6 0.8 2.5 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family PAS_8 PF13188.7 EMT53498.1 - 2.3e-09 37.0 0.0 1.7e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 PAS domain Mg_chelatase PF01078.21 EMT53498.1 - 5.5e-09 35.7 0.1 9.1e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI PAS PF00989.25 EMT53498.1 - 1.4e-07 31.5 0.0 6.6e-07 29.3 0.0 2.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EMT53498.1 - 6.3e-05 23.2 0.8 0.00035 20.8 0.1 2.6 4 0 0 4 4 3 1 PAS domain AAA_5 PF07728.14 EMT53498.1 - 7.4e-05 22.8 0.0 0.00029 20.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PAS_7 PF12860.7 EMT53498.1 - 0.00015 21.9 0.1 0.0037 17.4 0.1 2.6 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EMT53498.1 - 0.00016 21.9 0.0 0.0014 18.9 0.0 2.7 2 1 0 2 2 1 1 PAS fold HTH_50 PF18024.1 EMT53498.1 - 0.00031 20.3 0.0 0.0084 15.7 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain PAS_10 PF13596.6 EMT53498.1 - 0.0011 19.5 0.1 0.19 12.3 0.0 2.9 2 1 0 2 2 2 1 PAS domain AAA PF00004.29 EMT53498.1 - 0.0063 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EMT53498.1 - 0.024 14.8 0.0 0.068 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) UPF0175 PF03683.13 EMT53498.1 - 0.024 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_17 PF12728.7 EMT53498.1 - 0.045 13.9 0.0 2.5 8.4 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 EMT53498.1 - 0.07 12.9 0.1 0.5 10.2 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 EMT53498.1 - 0.089 12.9 0.2 0.72 10.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 EMT53498.1 - 0.16 11.9 1.7 35 4.3 0.0 3.6 4 0 0 4 4 3 0 AsnC-type helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EMT53498.1 - 0.17 11.3 0.0 0.41 10.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Gram_pos_anchor PF00746.21 EMT53499.1 - 0.026 14.4 0.4 0.042 13.8 0.4 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Acetyltransf_1 PF00583.25 EMT53501.1 - 2.1e-08 34.4 0.0 3.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EMT53501.1 - 0.029 14.4 0.0 5.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CN_hydrolase PF00795.22 EMT53502.1 - 1.8e-29 102.9 0.0 2.2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_M20 PF01546.28 EMT53503.1 - 2.4e-26 92.7 0.0 3.7e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EMT53503.1 - 4.7e-11 42.7 0.0 7.4e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 EMT53503.1 - 1.4e-08 34.6 0.0 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain PCP_red PF08369.10 EMT53503.1 - 0.28 11.4 1.5 6 7.2 0.2 2.5 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Amidohydro_3 PF07969.11 EMT53504.1 - 5.8e-101 339.3 0.2 6.8e-101 339.1 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EMT53504.1 - 1e-22 81.0 0.0 5.4e-19 68.7 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family SSF PF00474.17 EMT53505.1 - 1.6e-17 63.5 24.6 2.3e-17 62.9 24.6 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF5534 PF17686.1 EMT53505.1 - 0.077 13.3 1.0 0.13 12.5 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5534) Phage_tail_X PF05489.12 EMT53505.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Phage Tail Protein X DUF3311 PF11755.8 EMT53506.1 - 5.6e-23 80.6 2.5 6.1e-23 80.5 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3311) DUF3796 PF12676.7 EMT53506.1 - 0.12 12.8 0.3 0.13 12.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) TRAM1 PF08390.11 EMT53506.1 - 0.12 12.0 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 TRAM1-like protein PucR PF07905.11 EMT53507.1 - 3.5e-21 75.7 0.0 8.4e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 EMT53507.1 - 1e-18 66.9 1.0 2.4e-18 65.7 0.3 2.0 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 EMT53507.1 - 7e-18 65.0 4.6 1.6e-17 63.8 0.2 3.3 3 1 0 3 3 3 1 GGDEF-like domain DUF2089 PF09862.9 EMT53507.1 - 0.092 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Phage_NinH PF06322.11 EMT53507.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Phage NinH protein ABC_tran PF00005.27 EMT53508.1 - 1.4e-44 152.0 0.0 2.6e-22 79.8 0.0 2.7 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EMT53508.1 - 4.2e-21 74.8 3.9 4.2e-21 74.8 3.9 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EMT53508.1 - 6.6e-12 45.8 7.1 0.0007 19.5 0.0 4.4 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT53508.1 - 7e-08 32.2 0.9 0.013 15.0 0.1 3.2 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMT53508.1 - 0.00013 21.6 0.1 0.007 16.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EMT53508.1 - 0.00079 19.5 0.0 0.36 10.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EMT53508.1 - 0.0043 17.6 0.4 0.0043 17.6 0.4 3.6 2 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EMT53508.1 - 0.0077 16.2 0.2 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 EMT53508.1 - 0.02 14.6 0.0 0.02 14.6 0.0 3.2 2 1 2 4 4 3 0 AAA ATPase domain AAA PF00004.29 EMT53508.1 - 0.043 14.2 0.5 33 4.9 0.0 3.7 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EMT53508.1 - 0.057 13.8 0.2 8.6 6.8 0.0 3.2 3 0 0 3 3 3 0 RNA helicase Dynamin_N PF00350.23 EMT53508.1 - 0.083 12.9 0.1 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family RuvB_N PF05496.12 EMT53508.1 - 0.11 12.3 0.0 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EMT53508.1 - 0.12 12.8 0.0 1.4 9.3 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EMT53508.1 - 0.12 12.1 0.1 11 5.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EMT53508.1 - 0.63 10.3 4.5 35 4.7 0.1 3.8 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 EMT53510.1 - 4.5e-35 121.1 0.0 6.4e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter CysA_C_terminal PF17850.1 EMT53510.1 - 1.6e-12 47.8 1.8 2.8e-12 47.0 0.8 2.1 2 0 0 2 2 1 1 CysA C-terminal regulatory domain TOBE_3 PF12857.7 EMT53510.1 - 1.8e-12 46.9 0.1 5.5e-12 45.4 0.1 1.9 1 0 0 1 1 1 1 TOBE-like domain AAA_21 PF13304.6 EMT53510.1 - 8.3e-11 42.2 1.4 3.6e-05 23.7 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT53510.1 - 8.2e-07 28.7 0.0 5e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMT53510.1 - 2.6e-05 24.7 0.4 5.5e-05 23.6 0.4 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT53510.1 - 0.00014 22.1 0.2 0.0013 19.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EMT53510.1 - 0.00016 21.4 0.0 0.44 10.2 0.0 2.5 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EMT53510.1 - 0.0013 18.4 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT53510.1 - 0.0016 19.0 0.0 0.0028 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EMT53510.1 - 0.0018 17.7 0.0 0.47 9.8 0.0 2.4 1 1 1 2 2 2 1 Bacterial TniB protein NACHT PF05729.12 EMT53510.1 - 0.0033 17.4 1.4 0.036 14.0 0.1 2.6 2 1 1 3 3 3 1 NACHT domain AAA_33 PF13671.6 EMT53510.1 - 0.0036 17.5 0.5 0.035 14.3 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMT53510.1 - 0.0042 16.7 0.1 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EMT53510.1 - 0.0055 17.0 0.0 0.02 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EMT53510.1 - 0.0063 16.4 0.0 0.017 15.0 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase ABC_ATPase PF09818.9 EMT53510.1 - 0.0074 15.1 0.2 0.39 9.5 0.0 2.6 2 1 0 2 2 2 1 Predicted ATPase of the ABC class ATPase PF06745.13 EMT53510.1 - 0.0094 15.3 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 1 KaiC SbcCD_C PF13558.6 EMT53510.1 - 0.0099 16.1 0.1 0.088 13.1 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EMT53510.1 - 0.013 15.3 0.0 0.048 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EMT53510.1 - 0.017 15.5 0.0 0.11 12.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EMT53510.1 - 0.025 15.1 0.0 0.087 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain TOBE_2 PF08402.10 EMT53510.1 - 0.028 14.6 0.9 0.33 11.1 0.1 2.7 3 0 0 3 3 2 0 TOBE domain TOBE PF03459.17 EMT53510.1 - 0.033 14.5 0.0 0.24 11.7 0.0 2.3 2 0 0 2 2 2 0 TOBE domain DLIC PF05783.11 EMT53510.1 - 0.055 12.3 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_5 PF07728.14 EMT53510.1 - 0.059 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 EMT53510.1 - 0.092 12.2 0.0 3.4 7.1 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein GIIM PF08388.11 EMT53510.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Group II intron, maturase-specific domain AAA_14 PF13173.6 EMT53510.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EMT53510.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RecA PF00154.21 EMT53510.1 - 0.2 11.1 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein cobW PF02492.19 EMT53510.1 - 0.21 11.2 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain BPD_transp_1 PF00528.22 EMT53511.1 - 5.7e-18 65.3 12.1 5.7e-18 65.3 12.1 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2273 PF10031.9 EMT53511.1 - 0.046 13.7 0.2 0.046 13.7 0.2 4.0 5 0 0 5 5 5 0 Small integral membrane protein (DUF2273) DUF4293 PF14126.6 EMT53511.1 - 2.1 8.6 9.3 1.3 9.3 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) BPD_transp_1 PF00528.22 EMT53512.1 - 1.1e-23 83.9 19.0 1.1e-23 83.9 19.0 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_11 PF13531.6 EMT53513.1 - 3e-44 151.5 0.0 3.6e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT53513.1 - 6.6e-19 69.0 3.7 8.5e-19 68.6 3.7 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EMT53513.1 - 1.2e-08 34.7 0.2 7.5e-07 28.8 0.1 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein PBP_like PF12727.7 EMT53513.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.6 1 1 0 1 1 1 1 PBP superfamily domain PMSR PF01625.21 EMT53513.1 - 0.014 15.5 0.2 4.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Peptide methionine sulfoxide reductase MOSC PF03473.17 EMT53514.1 - 6.5e-23 81.2 0.0 9.3e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 MOSC domain 3-alpha PF03475.14 EMT53514.1 - 9e-15 54.3 0.0 1.6e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 3-alpha domain DUF3846 PF12957.7 EMT53515.1 - 5.1e-06 26.7 0.0 6.4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3846) dUTPase PF00692.19 EMT53516.1 - 1.1e-21 76.9 0.0 2.4e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 dUTPase Ribonuc_red_sm PF00268.21 EMT53517.1 - 7.8e-81 271.6 2.6 9.9e-81 271.2 2.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Phenol_Hydrox PF02332.18 EMT53517.1 - 0.0052 16.4 0.3 0.026 14.1 0.2 2.0 2 0 0 2 2 2 1 Methane/Phenol/Toluene Hydroxylase Acetyltransf_4 PF13420.7 EMT53517.1 - 0.047 13.8 0.6 8.4 6.5 0.1 2.4 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain 2-oxogl_dehyd_N PF16078.5 EMT53517.1 - 0.12 11.9 2.0 0.3 10.7 0.0 2.6 3 0 0 3 3 3 0 2-oxoglutarate dehydrogenase N-terminus Ribonuc_red_lgC PF02867.15 EMT53518.1 - 2.4e-156 521.4 0.0 1.4e-154 515.5 0.0 2.1 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EMT53518.1 - 1.1e-21 76.6 1.6 2.1e-21 75.7 0.0 2.4 3 0 0 3 3 3 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EMT53518.1 - 3.8e-18 65.8 0.9 7.4e-18 64.9 0.1 2.0 2 0 0 2 2 2 1 ATP cone domain RNR_N PF08343.10 EMT53518.1 - 0.053 13.6 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal DUF4830 PF16112.5 EMT53519.1 - 0.043 14.3 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4830) UPF0176_N PF17773.1 EMT53520.1 - 1.3e-26 92.7 0.0 2.8e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 EMT53520.1 - 4.5e-17 62.2 15.6 7.8e-17 61.4 15.6 1.4 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 EMT53520.1 - 1.2e-12 48.3 0.0 2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Amidase PF01425.21 EMT53521.1 - 1.7e-87 294.3 0.0 5e-85 286.2 0.0 2.0 1 1 0 1 1 1 1 Amidase DUF4173 PF13777.6 EMT53522.1 - 0.0092 15.4 0.6 0.011 15.2 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4173) Cyt_c_ox_IV PF12270.8 EMT53522.1 - 0.014 15.5 2.6 0.022 14.9 2.6 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Wzy_C PF04932.15 EMT53522.1 - 0.033 13.8 0.1 0.034 13.8 0.1 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF3093 PF11292.8 EMT53522.1 - 0.047 13.9 0.9 0.055 13.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) CBP_BcsG PF11658.8 EMT53522.1 - 0.075 11.4 0.1 0.084 11.3 0.1 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG VP7 PF00434.18 EMT53522.1 - 0.079 12.1 0.1 0.079 12.1 0.1 1.2 1 0 0 1 1 1 0 Glycoprotein VP7 DUF4389 PF14333.6 EMT53522.1 - 0.64 10.0 4.9 1 9.4 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) ATPgrasp_YheCD PF14398.6 EMT53523.1 - 2.6e-83 279.2 0.1 3e-83 279.0 0.1 1.0 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EMT53523.1 - 1.8e-09 37.3 0.1 1.4e-07 31.1 0.1 2.2 1 1 0 1 1 1 1 Sugar-transfer associated ATP-grasp TTL PF03133.15 EMT53523.1 - 0.0034 16.6 0.0 0.67 9.0 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family GSH-S_ATP PF02955.16 EMT53523.1 - 0.0062 15.9 0.1 0.074 12.4 0.1 2.4 1 1 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain PseudoU_synth_2 PF00849.22 EMT53524.1 - 2.9e-35 121.7 1.9 3.7e-35 121.4 1.9 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase Thioredoxin PF00085.20 EMT53525.1 - 4.5e-21 74.8 0.1 5.5e-21 74.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EMT53525.1 - 2.2e-07 30.7 0.1 2.7e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMT53525.1 - 4.7e-07 30.2 0.2 1.3e-06 28.8 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMT53525.1 - 5.5e-06 26.6 0.0 2.2e-05 24.7 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EMT53525.1 - 1.9e-05 24.6 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EMT53525.1 - 6.5e-05 23.0 0.1 9.6e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EMT53525.1 - 0.00011 22.0 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin DIM1 PF02966.16 EMT53525.1 - 0.0062 16.3 0.0 0.0066 16.2 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 TraF PF13728.6 EMT53525.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein DUF953 PF06110.11 EMT53525.1 - 0.098 12.3 0.4 0.19 11.4 0.4 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) LysR_substrate PF03466.20 EMT53526.1 - 7e-53 179.1 0.7 1.2e-52 178.4 0.7 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT53526.1 - 2.3e-23 81.9 0.4 4.4e-23 81.0 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EMT53526.1 - 0.0022 17.7 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 EMT53526.1 - 0.024 14.7 0.2 0.061 13.4 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 EMT53526.1 - 0.057 13.3 0.7 0.13 12.1 0.3 1.9 2 0 0 2 2 2 0 MarR family Aconitase PF00330.20 EMT53527.1 - 7.6e-163 542.8 0.1 8.6e-163 542.6 0.1 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 EMT53527.1 - 0.0072 15.1 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF521) PT-VENN PF04829.13 EMT53527.1 - 0.12 12.4 0.0 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Aconitase_C PF00694.19 EMT53528.1 - 2.6e-37 128.1 0.0 3.5e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain AMP-binding PF00501.28 EMT53529.1 - 5e-113 377.9 0.0 6.1e-113 377.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMT53529.1 - 6.7e-19 68.7 0.1 1.5e-18 67.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2249 PF10006.9 EMT53529.1 - 0.045 13.6 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) DUF4399 PF14347.6 EMT53530.1 - 0.057 13.8 0.2 0.51 10.8 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4399) DUF2970 PF11174.8 EMT53530.1 - 0.13 12.1 5.1 0.2 11.5 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DUF2846 PF11008.8 EMT53530.1 - 0.17 11.9 0.0 0.56 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2846) DUF520 PF04461.13 EMT53531.1 - 1.8e-62 210.2 7.1 2.1e-62 210.0 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) KH_5 PF13184.6 EMT53531.1 - 0.0066 16.5 2.3 0.018 15.1 2.3 1.7 1 0 0 1 1 1 1 NusA-like KH domain KH_1 PF00013.29 EMT53531.1 - 0.035 13.9 1.5 0.035 13.9 1.5 1.9 2 1 0 2 2 2 0 KH domain adh_short_C2 PF13561.6 EMT53532.1 - 7.3e-59 199.2 0.1 9.7e-59 198.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT53532.1 - 1e-47 162.1 0.1 1.3e-47 161.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT53532.1 - 5.1e-10 39.5 0.3 8.3e-10 38.9 0.3 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMT53532.1 - 0.0095 15.3 0.0 0.019 14.4 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 EMT53532.1 - 0.019 14.3 0.1 0.035 13.4 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 EMT53532.1 - 0.051 13.8 0.0 1.1 9.6 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ACR_tran PF00873.19 EMT53533.1 - 1.2e-191 639.0 36.6 1.4e-191 638.8 36.6 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EMT53533.1 - 2.8e-08 33.1 42.2 1e-05 24.7 13.8 3.2 2 1 0 2 2 2 2 MMPL family HMA PF00403.26 EMT53533.1 - 7.7e-07 29.5 2.5 0.13 12.7 0.9 5.0 5 0 0 5 5 5 1 Heavy-metal-associated domain AsnC_trans_reg PF01037.21 EMT53533.1 - 0.001 19.0 0.0 0.59 10.1 0.0 4.3 5 0 0 5 5 5 1 Lrp/AsnC ligand binding domain POTRA_1 PF08478.10 EMT53533.1 - 0.0033 17.7 0.1 0.073 13.4 0.0 3.2 3 0 0 3 3 3 1 POTRA domain, FtsQ-type YjbH PF06082.11 EMT53533.1 - 0.016 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF4434 PF14488.6 EMT53533.1 - 0.029 14.4 0.1 0.085 12.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) FeS_assembly_P PF01883.19 EMT53533.1 - 0.055 13.6 8.2 21 5.4 0.1 6.0 5 1 1 6 6 6 0 Iron-sulfur cluster assembly protein CinA_KH PF18146.1 EMT53533.1 - 0.22 11.7 1.1 18 5.6 0.7 3.4 2 1 1 3 3 3 0 Damage-inducible protein CinA KH domain DUF4763 PF15960.5 EMT53533.1 - 0.27 10.5 1.6 0.89 8.8 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) Holin_BhlA PF10960.8 EMT53533.1 - 2.5 8.1 5.2 0.85 9.6 0.5 2.7 3 0 0 3 3 2 0 BhlA holin family Spore_YhcN_YlaJ PF09580.10 EMT53533.1 - 6.1 6.9 9.2 1.5 8.9 2.0 2.8 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) HlyD_D23 PF16576.5 EMT53534.1 - 8.1e-19 67.7 13.1 2.5e-17 62.8 10.5 2.9 2 1 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EMT53534.1 - 7.8e-18 65.1 12.1 7.9e-17 61.9 3.3 3.0 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EMT53534.1 - 3.6e-07 29.9 0.1 3.6e-07 29.9 0.1 3.2 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 EMT53534.1 - 2.6e-05 24.0 0.5 0.14 12.0 0.0 3.4 2 0 0 2 2 2 2 Biotin-requiring enzyme ALP_N PF17989.1 EMT53534.1 - 0.016 15.3 0.4 0.035 14.3 0.4 1.6 1 0 0 1 1 1 0 Actin like proteins N terminal domain GGA_N-GAT PF18308.1 EMT53534.1 - 0.05 13.2 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 GGA N-GAT domain OEP PF02321.18 EMT53534.1 - 8 6.2 17.2 13 5.6 12.8 2.8 2 1 0 2 2 2 0 Outer membrane efflux protein Peptidase_M3 PF01432.20 EMT53535.1 - 1.4e-77 261.9 7.4 1.4e-77 261.9 7.4 1.8 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M3_N PF08439.10 EMT53535.1 - 1.2e-26 92.7 0.3 2.2e-25 88.7 0.2 3.1 3 0 0 3 3 3 1 Oligopeptidase F eIF3_N PF09440.10 EMT53535.1 - 0.019 15.4 5.4 0.49 10.8 0.2 3.1 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain HEAT_2 PF13646.6 EMT53535.1 - 0.07 13.5 0.1 0.9 10.0 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats UDPG_MGDP_dh_N PF03721.14 EMT53536.1 - 6e-56 189.0 0.0 9.3e-56 188.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EMT53536.1 - 3.2e-36 123.4 0.0 5.8e-36 122.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EMT53536.1 - 1.6e-31 108.8 0.0 1.4e-29 102.6 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 EMT53536.1 - 1.6e-05 24.9 0.0 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EMT53536.1 - 1.8e-05 25.0 0.1 7e-05 23.0 0.0 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EMT53536.1 - 4.6e-05 23.1 0.0 8.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 EMT53536.1 - 8.1e-05 22.0 0.1 0.00028 20.2 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMT53536.1 - 8.6e-05 22.8 0.1 0.00023 21.4 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 EMT53536.1 - 0.00073 20.1 0.1 0.079 13.6 0.0 3.3 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 EMT53536.1 - 0.0013 18.7 0.0 0.0042 17.1 0.0 1.9 3 0 0 3 3 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 EMT53536.1 - 0.0031 16.9 0.0 0.0051 16.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N PF00107.26 EMT53536.1 - 0.0073 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DAO PF01266.24 EMT53536.1 - 0.0091 15.6 0.5 0.025 14.2 0.5 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMT53536.1 - 0.044 13.0 0.1 0.076 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 EMT53536.1 - 0.055 12.8 0.1 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EMT53536.1 - 0.067 13.8 0.1 0.22 12.1 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.24 EMT53536.1 - 0.071 13.5 0.2 0.37 11.2 0.2 2.2 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EMT53536.1 - 0.094 13.2 0.1 0.46 11.0 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Glycos_transf_1 PF00534.20 EMT53537.1 - 9.8e-36 122.9 0.0 1.6e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT53537.1 - 5.4e-29 101.3 0.0 9.4e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT53537.1 - 5.6e-18 65.5 0.2 3.2e-15 56.6 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EMT53537.1 - 9.1e-11 42.0 0.0 3.2e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EMT53537.1 - 3.6e-09 37.3 0.1 7.5e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EMT53537.1 - 0.14 12.2 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like Epimerase PF01370.21 EMT53538.1 - 3.3e-55 187.2 0.0 4.6e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMT53538.1 - 4.8e-54 184.0 0.0 7.5e-54 183.3 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMT53538.1 - 3e-15 56.0 0.0 4e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMT53538.1 - 7.2e-15 54.8 0.0 9.6e-11 41.3 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EMT53538.1 - 6.3e-13 48.5 0.0 2.5e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EMT53538.1 - 1.6e-10 40.6 0.0 2.8e-10 39.8 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EMT53538.1 - 0.0015 18.4 0.0 0.0034 17.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EMT53538.1 - 0.0027 17.2 0.1 0.0099 15.3 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT53538.1 - 0.13 12.1 0.3 1.4 8.8 0.1 2.4 3 0 0 3 3 3 0 KR domain Ldh_1_N PF00056.23 EMT53538.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Glycos_transf_2 PF00535.26 EMT53539.1 - 1.7e-26 93.0 0.0 3.2e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMT53539.1 - 1.7e-08 34.6 0.0 3.1e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EMT53539.1 - 9.7e-07 28.5 0.8 1.8e-05 24.4 0.8 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EMT53539.1 - 0.003 17.5 0.0 0.0082 16.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 NTP_transferase PF00483.23 EMT53540.1 - 3.4e-44 151.3 0.0 4.3e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EMT53540.1 - 1.4e-11 45.0 0.0 1.9e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EMT53540.1 - 1.3e-05 24.4 0.2 2.2e-05 23.6 0.2 1.4 1 1 0 1 1 1 1 L-fucokinase Hexapep PF00132.24 EMT53540.1 - 0.00015 21.3 4.1 0.0037 16.9 0.5 3.5 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Glycos_transf_1 PF00534.20 EMT53541.1 - 2.7e-36 124.7 0.0 6.8e-36 123.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT53541.1 - 2.2e-23 83.2 0.0 4e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT53541.1 - 3.3e-15 56.5 1.8 9.9e-15 54.9 0.9 2.1 2 1 1 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EMT53541.1 - 8.2e-09 36.1 0.0 2.3e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EMT53541.1 - 6.5e-06 26.5 0.0 2.2e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 L51_S25_CI-B8 PF05047.16 EMT53541.1 - 0.14 12.1 0.9 0.43 10.5 0.1 2.3 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF737 PF05300.11 EMT53542.1 - 0.047 14.0 5.5 0.046 14.1 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) CCDC-167 PF15188.6 EMT53542.1 - 0.12 12.7 5.2 0.096 13.0 4.1 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4047 PF13256.6 EMT53542.1 - 0.38 10.9 4.9 0.47 10.6 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DnaB_2 PF07261.11 EMT53543.1 - 1.7e-24 85.4 1.2 1.2e-23 82.7 0.1 2.5 2 1 0 2 2 2 1 Replication initiation and membrane attachment HTH_36 PF13730.6 EMT53543.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Acetone_carb_G PF08882.11 EMT53543.1 - 0.038 14.1 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit PadR PF03551.14 EMT53543.1 - 0.067 13.2 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PDGF_N PF04692.13 EMT53543.1 - 0.097 13.5 0.5 0.21 12.4 0.1 1.8 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region MarR PF01047.22 EMT53543.1 - 0.16 11.9 1.2 0.33 10.9 0.1 2.1 3 0 0 3 3 3 0 MarR family tRNA-synt_2 PF00152.20 EMT53544.1 - 3.5e-87 292.4 0.0 4.4e-87 292.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMT53544.1 - 1.8e-12 47.1 0.1 3.1e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMT53544.1 - 0.065 12.7 0.0 15 4.9 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Sbi-IV PF11621.8 EMT53545.1 - 0.1 12.9 3.8 0.39 11.1 1.6 3.2 2 0 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI AAA PF00004.29 EMT53546.1 - 1.1e-40 139.1 0.0 5.1e-40 136.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 EMT53546.1 - 6.8e-34 117.4 2.0 1.2e-31 110.0 2.0 2.5 1 1 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 EMT53546.1 - 1.9e-12 46.8 0.0 4.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EMT53546.1 - 1.4e-06 28.6 0.2 4.4e-06 26.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EMT53546.1 - 1.7e-06 28.1 0.3 5.1e-05 23.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMT53546.1 - 1.2e-05 25.8 0.1 7.7e-05 23.1 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EMT53546.1 - 1.2e-05 25.1 0.2 0.00013 21.8 0.1 2.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMT53546.1 - 0.00018 21.8 0.3 0.0022 18.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 EMT53546.1 - 0.00031 20.2 0.3 0.0012 18.2 0.3 1.9 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.6 EMT53546.1 - 0.00043 20.1 0.1 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMT53546.1 - 0.00084 19.1 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EMT53546.1 - 0.00091 18.5 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) MCM PF00493.23 EMT53546.1 - 0.00096 18.3 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 EMT53546.1 - 0.0022 17.7 0.2 0.047 13.4 0.2 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 EMT53546.1 - 0.0038 17.8 0.2 0.028 14.9 0.0 2.6 3 1 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 EMT53546.1 - 0.012 15.6 0.5 0.24 11.3 0.0 2.7 1 1 1 2 2 2 0 NTPase Mg_chelatase PF01078.21 EMT53546.1 - 0.013 14.9 0.0 0.036 13.4 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EMT53546.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EMT53546.1 - 0.02 14.7 0.1 0.074 12.8 0.1 2.1 2 1 0 2 2 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 EMT53546.1 - 0.02 14.9 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EMT53546.1 - 0.036 14.5 0.5 0.72 10.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EMT53546.1 - 0.054 12.7 0.7 0.07 12.3 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain RNA_helicase PF00910.22 EMT53546.1 - 0.056 13.8 0.0 0.15 12.5 0.0 1.7 2 0 0 2 2 1 0 RNA helicase T2SSE PF00437.20 EMT53546.1 - 0.071 12.1 0.0 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.6 EMT53546.1 - 0.074 13.3 0.1 0.28 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EMT53546.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMT53546.1 - 0.082 13.2 0.9 0.37 11.1 0.9 2.4 1 1 0 1 1 1 0 AAA domain DUF5590 PF17881.1 EMT53548.1 - 8.8e-11 41.7 0.3 2.7e-10 40.1 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5590) JSRP PF15312.6 EMT53548.1 - 0.087 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein DUF945 PF06097.11 EMT53548.1 - 0.11 11.5 0.5 0.14 11.2 0.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Amidohydro_1 PF01979.20 EMT53550.1 - 1.5e-72 244.8 0.5 1.5e-72 244.8 0.5 1.4 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMT53550.1 - 1.9e-24 87.0 1.7 1.4e-17 64.3 0.4 2.4 2 0 0 2 2 2 2 Amidohydrolase family Peptidase_M24_C PF16188.5 EMT53550.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 Put_DNA-bind_N PF06971.13 EMT53551.1 - 1.9e-21 75.8 0.3 4.3e-21 74.7 0.3 1.6 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus CoA_binding PF02629.19 EMT53551.1 - 3.6e-20 72.4 0.2 7e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 EMT53551.1 - 0.00012 22.9 0.1 0.00017 22.4 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_3 PF13727.6 EMT53551.1 - 0.00056 20.0 0.1 0.00091 19.3 0.1 1.3 1 0 0 1 1 1 1 CoA-binding domain RFX_DNA_binding PF02257.15 EMT53551.1 - 0.0095 16.5 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain GARS_N PF02844.15 EMT53551.1 - 0.016 15.9 0.1 0.026 15.3 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain F420_oxidored PF03807.17 EMT53551.1 - 0.032 14.8 0.3 0.09 13.4 0.4 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EMT53551.1 - 0.058 13.7 0.1 0.086 13.1 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DNA_photolyase PF00875.18 EMT53551.1 - 0.096 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 DNA photolyase PglD_N PF17836.1 EMT53551.1 - 0.1 13.3 0.1 0.18 12.4 0.1 1.4 1 0 0 1 1 1 0 PglD N-terminal domain Lactamase_B PF00753.27 EMT53552.1 - 1.3e-06 28.6 0.0 2.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EMT53552.1 - 0.11 11.9 0.0 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain Helicase_C_2 PF13307.6 EMT53553.1 - 6.1e-41 140.4 0.0 1.6e-40 139.1 0.0 1.7 2 0 0 2 2 2 1 Helicase C-terminal domain RNase_T PF00929.24 EMT53553.1 - 1.2e-34 120.2 0.0 2.1e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DEAD PF00270.29 EMT53553.1 - 5.3e-09 36.1 0.1 2.4e-05 24.2 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EMT53553.1 - 1.2e-07 31.9 0.0 1.1e-06 28.8 0.1 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF5051 PF16473.5 EMT53553.1 - 5e-07 29.8 0.0 9.7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like DEAD_2 PF06733.15 EMT53553.1 - 6.3e-07 29.2 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C PF00271.31 EMT53553.1 - 9.3e-06 26.0 0.0 0.00018 21.8 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain CofC PF01983.16 EMT53553.1 - 0.068 12.3 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Guanylyl transferase CofC like DUF2075 PF09848.9 EMT53553.1 - 0.078 12.2 0.1 1.2 8.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EMT53553.1 - 0.11 12.8 0.2 4.9 7.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain DNA_pol_A_exo1 PF01612.20 EMT53553.1 - 0.14 11.8 1.4 1.4 8.6 0.0 3.2 4 0 0 4 4 4 0 3'-5' exonuclease TPR_2 PF07719.17 EMT53554.1 - 7.1e-18 63.2 21.6 0.0016 18.4 0.1 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EMT53554.1 - 1e-15 58.1 11.3 2e-05 25.1 0.0 6.3 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 EMT53554.1 - 4.9e-13 48.3 10.1 0.027 14.3 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMT53554.1 - 5.4e-13 48.0 11.1 0.0014 18.7 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMT53554.1 - 3e-12 46.9 13.7 1.8e-07 31.6 0.7 6.4 4 2 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMT53554.1 - 3e-11 43.1 22.6 0.083 13.7 0.3 8.2 6 3 2 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 EMT53554.1 - 8.3e-11 41.8 9.2 0.72 10.6 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMT53554.1 - 3.8e-08 33.2 7.9 0.21 12.1 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMT53554.1 - 1.9e-07 30.6 12.5 0.23 11.6 0.1 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMT53554.1 - 3.6e-07 30.4 16.1 0.12 12.6 0.9 6.6 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EMT53554.1 - 1.1e-05 25.4 14.3 0.00013 22.0 1.5 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMT53554.1 - 1.2e-05 24.9 0.2 0.00091 18.9 0.0 3.7 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 EMT53554.1 - 0.00031 20.9 3.7 0.019 15.2 0.0 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Lambda_Kil PF06301.11 EMT53554.1 - 0.048 13.3 1.1 0.16 11.6 0.0 2.4 3 0 0 3 3 3 0 Bacteriophage lambda Kil protein DUF2462 PF09495.10 EMT53554.1 - 0.1 13.3 1.1 0.21 12.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) TPR_20 PF14561.6 EMT53554.1 - 0.22 11.9 13.4 0.14 12.5 0.4 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat HemY_N PF07219.13 EMT53554.1 - 0.56 10.4 3.6 7.9 6.7 0.0 3.6 3 1 0 3 3 3 0 HemY protein N-terminus GramPos_pilinD1 PF16555.5 EMT53554.1 - 0.85 9.8 3.6 1.4 9.1 3.6 1.3 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain PPR PF01535.20 EMT53554.1 - 1 9.8 5.6 1.6e+02 2.9 0.0 5.3 5 0 0 5 5 5 0 PPR repeat TPR_10 PF13374.6 EMT53554.1 - 6.8 6.7 11.9 1.2 9.1 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Asp_decarbox PF02261.16 EMT53555.1 - 2.5e-55 185.3 0.6 2.9e-55 185.1 0.6 1.0 1 0 0 1 1 1 1 Aspartate decarboxylase Bet_v_1 PF00407.19 EMT53555.1 - 0.0054 16.6 0.1 0.97 9.3 0.0 2.1 2 0 0 2 2 2 2 Pathogenesis-related protein Bet v I family Pantoate_ligase PF02569.15 EMT53556.1 - 2e-109 364.9 0.0 2.3e-109 364.7 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase CTP_transf_like PF01467.26 EMT53556.1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Cytidylyltransferase-like Pantoate_transf PF02548.15 EMT53557.1 - 3.5e-118 393.7 0.2 4e-118 393.5 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EMT53557.1 - 1.9e-06 27.5 0.1 3.1e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.22 EMT53557.1 - 0.095 12.5 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase BPL_LplA_LipB PF03099.19 EMT53558.1 - 2.4e-17 63.1 0.0 4.5e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.12 EMT53558.1 - 6.3e-13 48.5 0.0 1.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 HTH domain BPL_LplA_LipB_2 PF16917.5 EMT53558.1 - 1.1e-09 38.1 0.0 2.1e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EMT53558.1 - 4.7e-06 26.4 0.1 1e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain HTH_24 PF13412.6 EMT53558.1 - 0.00021 20.8 0.0 0.0004 19.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 EMT53558.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PET10 PF17316.2 EMT53558.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Petite colonies protein 10 LexA_DNA_bind PF01726.16 EMT53558.1 - 0.15 11.8 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 LexA DNA binding domain PolyA_pol PF01743.20 EMT53559.1 - 6.8e-33 113.8 0.0 1.1e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.6 EMT53559.1 - 3.2e-26 92.1 0.7 4.9e-26 91.5 0.7 1.3 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative PolyA_pol_RNAbd PF12627.7 EMT53559.1 - 4.2e-14 52.1 1.4 8.3e-14 51.1 0.3 2.2 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A VGCC_alpha2 PF08473.11 EMT53559.1 - 0.14 10.9 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd Glycos_transf_1 PF00534.20 EMT53560.1 - 1.1e-38 132.5 0.0 2.2e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT53560.1 - 1.9e-31 109.3 0.3 3.6e-31 108.3 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT53560.1 - 1.8e-24 86.7 0.5 6.9e-24 84.7 0.3 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EMT53560.1 - 1.8e-14 54.5 0.0 1.9e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EMT53560.1 - 3e-14 53.2 0.0 5.5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EMT53560.1 - 3.1e-07 30.7 0.0 7.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EMT53560.1 - 4.1e-05 23.4 2.1 0.1 12.3 0.0 3.0 1 1 1 2 2 2 2 Starch synthase catalytic domain PIG-L PF02585.17 EMT53561.1 - 5.2e-20 72.4 0.0 7.3e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase MGS PF02142.22 EMT53562.1 - 1.1e-15 57.5 0.0 1.6e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 MGS-like domain DapB_C PF05173.14 EMT53563.1 - 8.1e-33 113.0 0.4 1.2e-32 112.5 0.4 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 EMT53563.1 - 1.1e-26 93.4 0.0 4.8e-26 91.3 0.0 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 EMT53563.1 - 0.016 15.4 0.1 0.14 12.4 0.1 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 EMT53563.1 - 0.037 14.7 0.0 0.12 13.1 0.0 1.8 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 EMT53563.1 - 0.043 14.3 0.0 0.078 13.5 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain Semialdhyde_dh PF01118.24 EMT53563.1 - 0.047 14.1 0.1 0.21 12.0 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EMT53563.1 - 0.07 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain MazG PF03819.17 EMT53564.1 - 1.5e-21 76.4 0.3 2.5e-21 75.6 0.1 1.5 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 EMT53564.1 - 0.00051 20.2 0.0 0.00096 19.4 0.0 1.6 1 1 0 1 1 1 1 MazG-like family PRA-PH PF01503.17 EMT53564.1 - 0.0031 17.9 0.2 0.0049 17.3 0.2 1.5 1 1 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase dUTPase_2 PF08761.11 EMT53564.1 - 0.0058 16.8 0.2 0.0071 16.5 0.2 1.2 1 0 0 1 1 1 1 dUTPase DUF3135 PF11333.8 EMT53564.1 - 0.0099 16.1 0.1 0.015 15.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3135) RRP7 PF12923.7 EMT53564.1 - 0.055 13.6 4.5 2 8.5 1.8 2.7 2 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain YitT_membrane PF02588.15 EMT53565.1 - 6.9e-65 218.3 20.7 9e-65 217.9 20.7 1.1 1 0 0 1 1 1 1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DUF2179 PF10035.9 EMT53565.1 - 9.9e-23 79.7 0.2 2e-22 78.7 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2179) Spore_YpjB PF09577.10 EMT53566.1 - 2.8e-60 204.0 3.3 3.4e-60 203.7 3.3 1.0 1 0 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) RmuC PF02646.16 EMT53566.1 - 0.0012 18.1 1.6 0.0025 17.0 0.3 2.1 2 1 0 2 2 2 1 RmuC family Pox_G5 PF04599.12 EMT53566.1 - 0.026 13.5 0.1 0.034 13.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein Mrr_N PF14338.6 EMT53566.1 - 0.048 13.8 0.5 0.22 11.7 0.1 2.0 2 0 0 2 2 2 0 Mrr N-terminal domain DIRP PF06584.13 EMT53566.1 - 0.21 11.8 1.7 3.8 7.7 0.1 2.6 2 1 0 2 2 2 0 DIRP MetOD2 PF18548.1 EMT53566.1 - 0.84 9.8 5.1 0.67 10.1 1.3 2.5 3 0 0 3 3 3 0 Metanogen output domain 2 PCRF PF03462.18 EMT53566.1 - 1.6 8.6 4.8 0.8 9.5 0.8 2.0 2 0 0 2 2 2 0 PCRF domain DUF1405 PF07187.11 EMT53567.1 - 6e-52 175.8 7.5 8.2e-52 175.4 7.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1405) Cytochrome_CBB3 PF13442.6 EMT53568.1 - 2.3e-10 40.7 1.1 3.3e-10 40.1 0.2 1.7 1 1 1 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_B_C PF00032.17 EMT53568.1 - 1.4e-09 38.1 0.2 1.4e-09 38.1 0.2 1.5 2 0 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_C PF00034.21 EMT53568.1 - 1.3e-06 29.5 0.7 1.9e-05 25.7 0.7 2.4 1 1 0 1 1 1 1 Cytochrome c DUF4131 PF13567.6 EMT53568.1 - 0.046 13.4 1.6 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cytochrome_B PF00033.19 EMT53569.1 - 2.8e-51 174.0 14.2 3.4e-51 173.8 14.2 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 EMT53569.1 - 6.9e-41 140.1 7.5 6.9e-41 140.1 7.5 1.6 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.20 EMT53569.1 - 0.00015 21.4 18.7 0.00025 20.7 5.9 2.2 1 1 1 2 2 2 2 Prokaryotic cytochrome b561 DUF373 PF04123.13 EMT53569.1 - 0.078 12.4 2.8 0.11 11.9 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4079 PF13301.6 EMT53569.1 - 0.088 13.0 2.9 0.15 12.2 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF4405 PF14358.6 EMT53569.1 - 3 8.5 22.2 0.16 12.5 6.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4405) Rieske PF00355.26 EMT53570.1 - 1e-11 44.6 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.10 EMT53570.1 - 3.1e-05 23.9 0.5 5.6e-05 23.1 0.5 1.4 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit UCR_Fe-S_N PF10399.9 EMT53570.1 - 0.0005 19.3 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF2487 PF10673.9 EMT53571.1 - 9.5e-09 35.4 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) IDEAL PF08858.10 EMT53572.1 - 6.3e-13 48.2 4.1 8.1e-13 47.9 4.1 1.2 1 0 0 1 1 1 1 IDEAL domain Gpi1 PF05024.15 EMT53573.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) TPR_19 PF14559.6 EMT53574.1 - 1.1e-21 77.1 27.0 2.5e-07 31.1 0.8 5.8 2 2 3 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EMT53574.1 - 1.3e-20 71.8 24.6 0.00053 19.9 0.1 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EMT53574.1 - 2.4e-20 72.9 15.9 1.7e-05 25.4 1.9 5.5 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 EMT53574.1 - 4.2e-14 52.0 23.1 0.013 16.3 1.0 8.0 2 2 6 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EMT53574.1 - 4.7e-14 51.3 18.6 0.016 15.3 0.1 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMT53574.1 - 5.3e-13 48.0 18.7 0.043 13.8 0.0 7.8 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EMT53574.1 - 1.4e-12 46.8 17.3 0.011 15.5 0.1 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMT53574.1 - 2e-11 44.0 24.9 0.0049 17.1 0.5 6.7 4 3 2 6 6 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EMT53574.1 - 3.8e-11 43.1 10.3 9.5e-05 22.6 1.0 4.7 1 1 5 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EMT53574.1 - 6.1e-08 32.8 18.3 0.037 14.7 0.1 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 EMT53574.1 - 6.8e-08 32.4 10.6 0.0053 17.3 0.6 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 EMT53574.1 - 1.5e-07 31.3 2.6 0.17 11.5 0.2 4.9 1 1 0 3 3 3 2 26S proteasome subunit RPN7 TPR_11 PF13414.6 EMT53574.1 - 2.3e-07 30.3 17.1 0.011 15.4 0.2 6.6 5 2 2 7 7 7 3 TPR repeat NARP1 PF12569.8 EMT53574.1 - 5.1e-07 29.0 7.3 0.009 15.0 0.1 3.9 1 1 4 5 5 5 3 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 EMT53574.1 - 1e-06 28.8 12.1 0.0058 16.7 0.1 4.8 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 EMT53574.1 - 2e-06 27.6 12.5 0.0012 18.6 1.5 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 EMT53574.1 - 2.6e-06 27.7 12.2 0.036 14.4 0.1 5.2 1 1 5 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EMT53574.1 - 2.6e-06 27.0 13.5 0.00015 21.2 3.9 3.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 EMT53574.1 - 4e-06 26.5 19.2 0.011 15.6 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMT53574.1 - 5.5e-06 26.4 4.0 0.3 11.6 0.0 5.2 6 1 0 6 6 3 2 Tetratricopeptide repeat PPR PF01535.20 EMT53574.1 - 7e-05 22.8 2.4 55 4.3 0.0 6.9 8 0 0 8 8 8 0 PPR repeat Clathrin PF00637.20 EMT53574.1 - 0.00031 20.6 6.1 0.00047 20.1 0.7 3.2 3 2 0 3 3 3 1 Region in Clathrin and VPS DUF3808 PF10300.9 EMT53574.1 - 0.0011 17.8 0.2 0.002 17.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) SRP_TPR_like PF17004.5 EMT53574.1 - 0.0032 17.5 5.6 1 9.4 0.9 3.8 2 1 2 4 4 4 1 Putative TPR-like repeat MIT PF04212.18 EMT53574.1 - 0.007 16.4 4.4 0.093 12.8 0.4 4.0 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain HEPN_AbiV PF18728.1 EMT53574.1 - 0.01 16.0 0.3 0.02 15.1 0.3 1.4 1 0 0 1 1 1 0 AbiV DUF2225 PF09986.9 EMT53574.1 - 0.019 14.7 0.7 1.7 8.3 0.1 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC5 PF12862.7 EMT53574.1 - 0.02 15.0 0.6 13 6.0 0.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 Alkyl_sulf_dimr PF14863.6 EMT53574.1 - 0.04 14.4 4.3 2.7 8.4 0.4 4.0 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation T2SSF PF00482.23 EMT53574.1 - 0.069 13.1 3.3 9.6 6.2 0.0 3.6 2 1 2 4 4 4 0 Type II secretion system (T2SS), protein F Fis1_TPR_C PF14853.6 EMT53574.1 - 1 9.5 9.2 23 5.2 0.0 4.8 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 EMT53574.1 - 1.2 9.2 8.1 0.73 9.9 0.6 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-HC2 PF13490.6 EMT53575.1 - 2.6e-13 49.9 2.9 4.5e-13 49.2 2.9 1.4 1 0 0 1 1 1 1 Putative zinc-finger DUF4131 PF13567.6 EMT53575.1 - 0.044 13.4 0.7 0.052 13.2 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Sigma70_r4_2 PF08281.12 EMT53576.1 - 6.8e-17 60.9 0.3 1.3e-16 60.0 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT53576.1 - 1.7e-16 59.8 0.5 3.3e-16 58.8 0.5 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EMT53576.1 - 1.8e-09 37.0 0.1 3.9e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 PCI PF01399.27 EMT53576.1 - 0.0039 17.7 3.8 0.13 12.8 0.2 2.3 2 0 0 2 2 2 2 PCI domain Sigma70_ECF PF07638.11 EMT53576.1 - 0.0088 16.0 1.9 0.018 15.0 1.9 1.4 1 1 0 1 1 1 1 ECF sigma factor HTH_16 PF12645.7 EMT53576.1 - 0.033 14.3 0.7 0.067 13.3 0.7 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r3 PF04539.16 EMT53576.1 - 0.046 13.8 0.5 3.8 7.7 0.0 2.9 3 0 0 3 3 3 0 Sigma-70 region 3 Amidohydro_1 PF01979.20 EMT53577.1 - 1.8e-07 30.8 0.0 2.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EMT53577.1 - 0.0013 19.0 0.2 0.0022 18.3 0.2 1.3 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 EMT53577.1 - 0.0027 17.3 0.0 0.036 13.5 0.0 2.4 3 0 0 3 3 3 1 Amidohydrolase family EPSP_synthase PF00275.20 EMT53578.1 - 2.7e-127 424.9 1.1 3.1e-127 424.7 1.1 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) PDH PF02153.17 EMT53579.1 - 2.6e-76 256.1 0.0 3.2e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Prephenate dehydrogenase ACT PF01842.25 EMT53579.1 - 7e-08 32.1 0.1 2.6e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 ACT domain F420_oxidored PF03807.17 EMT53579.1 - 1.8e-07 31.6 0.1 4.6e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EMT53579.1 - 1.8e-06 28.2 0.1 6.7e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EMT53579.1 - 0.0016 18.0 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 EMT53579.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 EMT53579.1 - 0.0031 16.9 0.1 0.0066 15.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACT_4 PF13291.6 EMT53579.1 - 0.0044 17.6 0.0 0.014 16.0 0.0 1.8 1 0 0 1 1 1 1 ACT domain UDPG_MGDP_dh_N PF03721.14 EMT53579.1 - 0.0076 15.8 1.0 0.091 12.3 0.5 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EMT53579.1 - 0.014 15.3 0.1 0.03 14.2 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EMT53579.1 - 0.027 14.5 0.2 0.7 9.9 0.2 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.24 EMT53579.1 - 0.046 13.3 0.5 0.079 12.5 0.4 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 EMT53579.1 - 0.057 13.7 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Aminotran_1_2 PF00155.21 EMT53580.1 - 1e-65 222.3 0.0 1.1e-65 222.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMT53580.1 - 2.1e-08 33.6 0.0 1.7e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Alliinase_C PF04864.13 EMT53580.1 - 0.00013 21.0 0.0 0.00031 19.8 0.0 1.5 1 1 1 2 2 2 1 Allinase Cys_Met_Meta_PP PF01053.20 EMT53580.1 - 0.0037 15.9 0.0 0.0064 15.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 EMT53580.1 - 0.055 12.0 0.0 0.085 11.4 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Trp_syntA PF00290.20 EMT53581.1 - 1.5e-92 309.1 0.0 1.8e-92 308.9 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 EMT53581.1 - 0.00075 19.0 0.1 0.0023 17.4 0.0 1.8 3 0 0 3 3 3 1 Histidine biosynthesis protein PcrB PF01884.17 EMT53581.1 - 0.016 14.7 0.0 0.1 12.0 0.0 2.0 2 0 0 2 2 2 0 PcrB family Peripla_BP_4 PF13407.6 EMT53581.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain PALP PF00291.25 EMT53582.1 - 1.7e-46 159.0 1.2 2.1e-46 158.7 1.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PRAI PF00697.22 EMT53583.1 - 1.7e-47 161.7 0.0 1.9e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase MlaC PF05494.12 EMT53583.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 MlaC protein IGPS PF00218.21 EMT53584.1 - 9.6e-90 300.2 0.1 1.1e-89 300.0 0.1 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 EMT53584.1 - 0.0012 18.1 0.1 0.0038 16.5 0.0 1.8 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 EMT53584.1 - 0.033 13.6 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF561 PF04481.12 EMT53584.1 - 0.052 12.7 0.1 0.09 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF561) FMN_dh PF01070.18 EMT53584.1 - 0.063 12.3 0.0 0.33 9.9 0.0 2.1 1 1 0 1 1 1 0 FMN-dependent dehydrogenase Glycos_transf_3 PF00591.21 EMT53585.1 - 6.2e-103 343.8 0.7 1.6e-102 342.4 0.2 1.7 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EMT53585.1 - 5.7e-19 67.7 2.6 5.2e-18 64.7 2.9 2.3 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain DUF348 PF03990.14 EMT53585.1 - 0.25 11.1 1.5 8.6 6.2 0.2 3.0 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain Chorismate_bind PF00425.18 EMT53586.1 - 9.6e-99 330.1 0.0 1.3e-98 329.7 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EMT53586.1 - 3.3e-42 144.1 0.0 8.2e-38 129.8 0.0 3.0 2 1 1 3 3 3 2 Anthranilate synthase component I, N terminal region CM_1 PF07736.11 EMT53587.1 - 7.7e-48 161.7 0.1 8.5e-48 161.6 0.1 1.0 1 0 0 1 1 1 1 Chorismate mutase type I DHQ_synthase PF01761.20 EMT53588.1 - 2.9e-102 341.3 0.1 3.7e-102 341.0 0.1 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EMT53588.1 - 4.1e-14 52.9 0.3 7.9e-14 52.0 0.3 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EMT53588.1 - 4.3e-13 48.8 2.8 8.8e-13 47.8 2.8 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Chorismate_synt PF01264.21 EMT53589.1 - 1.2e-124 415.3 1.8 1.4e-124 415.1 1.8 1.0 1 0 0 1 1 1 1 Chorismate synthase NAD_binding_11 PF14833.6 EMT53589.1 - 0.11 12.7 0.0 0.43 10.8 0.0 1.9 1 1 1 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CheR PF01739.18 EMT53590.1 - 3.6e-59 199.6 0.0 4.6e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 EMT53590.1 - 1.2e-14 53.7 0.5 2.5e-14 52.7 0.5 1.6 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_25 PF13649.6 EMT53590.1 - 6.9e-09 36.3 0.0 2.4e-06 28.2 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT53590.1 - 7.5e-08 33.0 0.0 3.8e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT53590.1 - 4.1e-05 24.2 0.1 0.00068 20.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT53590.1 - 0.00017 21.5 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT53590.1 - 0.00021 21.1 0.0 0.0061 16.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain NDK PF00334.19 EMT53591.1 - 2e-60 202.7 0.0 2.2e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Peptidase_S77 PF03420.13 EMT53591.1 - 0.033 13.8 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Prohead core protein serine protease polyprenyl_synt PF00348.17 EMT53592.1 - 2.7e-66 223.3 0.1 3.4e-66 222.9 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.19 EMT53592.1 - 0.022 14.3 0.4 0.081 12.4 0.4 2.1 1 1 0 1 1 1 0 Squalene/phytoene synthase VitK2_biosynth PF02621.14 EMT53593.1 - 2.9e-66 223.7 0.0 3.3e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis MbeD_MobD PF04899.12 EMT53593.1 - 0.12 12.5 0.2 0.34 11.1 0.2 1.8 1 1 0 1 1 1 0 MbeD/MobD like Flavoprotein PF02441.19 EMT53594.1 - 7.9e-18 64.7 0.0 9.4e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein UbiA PF01040.18 EMT53595.1 - 3e-53 180.7 22.5 3.9e-53 180.3 22.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ubie_methyltran PF01209.18 EMT53596.1 - 6.3e-84 280.9 0.0 7.4e-84 280.7 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EMT53596.1 - 5e-24 84.8 0.3 1.3e-23 83.5 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT53596.1 - 2.2e-23 82.7 0.1 3.5e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT53596.1 - 1.3e-19 70.4 0.0 1.8e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT53596.1 - 1.8e-14 53.9 0.0 2.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT53596.1 - 1.3e-13 51.6 0.0 2e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMT53596.1 - 6e-10 39.2 0.2 1.2e-09 38.2 0.2 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EMT53596.1 - 2.4e-07 30.6 0.0 3.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 EMT53596.1 - 1.4e-05 25.3 0.4 2.6e-05 24.4 0.4 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 EMT53596.1 - 7.6e-05 22.7 0.0 0.00029 20.8 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 EMT53596.1 - 0.00015 21.2 1.1 0.00024 20.5 0.3 1.7 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_20 PF12147.8 EMT53596.1 - 0.00096 18.4 0.1 0.0023 17.1 0.1 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_3 PF01596.17 EMT53596.1 - 0.0021 17.3 0.0 0.0032 16.7 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.17 EMT53596.1 - 0.0038 16.7 0.0 0.043 13.3 0.0 2.4 3 0 0 3 3 3 1 Putative methyltransferase UPF0020 PF01170.18 EMT53596.1 - 0.0051 16.5 0.0 0.052 13.2 0.1 2.4 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 EMT53596.1 - 0.013 15.2 0.2 0.042 13.6 0.1 1.9 1 1 1 2 2 2 0 Met-10+ like-protein GCD14 PF08704.10 EMT53596.1 - 0.014 15.0 0.0 0.036 13.8 0.0 1.6 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 EMT53596.1 - 0.023 14.2 0.1 0.038 13.5 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_29 PF03141.16 EMT53596.1 - 0.034 12.7 0.0 0.071 11.6 0.0 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltr_RsmB-F PF01189.17 EMT53596.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F HEPPP_synt_1 PF07307.11 EMT53597.1 - 9.6e-41 139.7 1.0 1.2e-40 139.4 1.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 polyprenyl_synt PF00348.17 EMT53597.1 - 0.03 13.4 0.3 0.075 12.1 0.1 1.7 2 0 0 2 2 2 0 Polyprenyl synthetase TrpBP PF02081.15 EMT53599.1 - 7.4e-40 134.6 2.5 8.7e-40 134.4 2.5 1.0 1 0 0 1 1 1 1 Tryptophan RNA-binding attenuator protein SLT PF01464.20 EMT53600.1 - 8.1e-28 96.4 0.0 1.2e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain MFS_1 PF07690.16 EMT53601.1 - 2.2e-22 79.5 50.1 1.2e-13 50.7 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT53601.1 - 1.3e-18 66.7 27.0 1.8e-18 66.2 27.0 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 EMT53601.1 - 5.5e-05 21.9 3.7 5.5e-05 21.9 3.7 2.8 1 1 1 2 2 2 2 MFS/sugar transport protein Mtc PF03820.17 EMT53601.1 - 0.0048 16.0 0.7 0.012 14.7 0.7 1.7 1 0 0 1 1 1 1 Tricarboxylate carrier DUF3099 PF11298.8 EMT53601.1 - 0.26 11.4 0.2 0.26 11.4 0.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3099) GTP_cyclohydroI PF01227.22 EMT53603.1 - 4.6e-80 267.3 0.1 5.1e-80 267.1 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EMT53603.1 - 0.011 15.9 0.0 0.035 14.3 0.0 1.7 2 0 0 2 2 2 0 QueF-like protein Adeno_GP19K PF04881.13 EMT53603.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus GP19K Bac_DNA_binding PF00216.21 EMT53604.1 - 2.1e-37 127.2 1.4 2.3e-37 127.0 1.4 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 EMT53604.1 - 1.3e-09 38.2 0.1 1.4e-09 38.1 0.1 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 EMT53604.1 - 0.00094 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 EMT53604.1 - 0.0012 19.0 0.1 0.0017 18.5 0.1 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 DUF2267 PF10025.9 EMT53604.1 - 0.0017 18.7 0.1 0.0023 18.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2267) HU-DNA_bdg PF14848.6 EMT53604.1 - 0.004 17.2 0.1 0.0071 16.3 0.1 1.6 1 1 0 1 1 1 1 DNA-binding domain SIS_2 PF13580.6 EMT53604.1 - 0.0045 17.0 0.1 0.0053 16.8 0.1 1.2 1 0 0 1 1 1 1 SIS domain HU-CCDC81_euk_1 PF14908.6 EMT53604.1 - 0.037 14.2 0.0 0.043 14.0 0.0 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 DUF1512 PF07431.12 EMT53604.1 - 0.076 12.0 0.1 0.085 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) VWA_3 PF13768.6 EMT53604.1 - 0.1 12.5 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain Spore_IV_A PF09547.10 EMT53605.1 - 4.2e-227 754.9 0.1 4.7e-227 754.8 0.1 1.0 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) MMR_HSR1 PF01926.23 EMT53605.1 - 0.0006 19.9 0.0 0.0021 18.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMT53605.1 - 0.0085 15.6 0.0 0.03 13.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EMT53605.1 - 0.011 16.1 0.0 0.16 12.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain Radical_SAM PF04055.21 EMT53605.1 - 0.049 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Radical SAM superfamily Septin PF00735.18 EMT53605.1 - 0.059 12.6 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.22 EMT53605.1 - 0.12 12.7 0.0 12 6.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF3939 PF13075.6 EMT53606.1 - 0.00039 20.5 0.8 0.18 11.8 0.2 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3939) Fer2 PF00111.27 EMT53607.1 - 2.8e-11 43.2 0.9 1.2e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 EMT53607.1 - 0.0075 16.3 0.3 0.017 15.2 0.1 1.7 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 EMT53608.1 - 5.4e-09 35.9 0.4 7.2e-09 35.5 0.4 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rpr2 PF04032.16 EMT53608.1 - 0.0046 17.2 0.1 0.0053 17.0 0.1 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Fer2_3 PF13085.6 EMT53608.1 - 0.07 13.2 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF2768 PF10966.8 EMT53609.1 - 7.4e-13 48.7 16.2 8.2e-13 48.6 16.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2768) Tetraspanin PF00335.20 EMT53609.1 - 1.4 8.6 9.0 1.5 8.5 9.0 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF2663 PF10864.8 EMT53609.1 - 1.7 9.0 6.0 1.9 8.9 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) SUR7 PF06687.12 EMT53609.1 - 4.7 6.8 14.4 5.3 6.6 14.4 1.0 1 0 0 1 1 1 0 SUR7/PalI family Pro-MCH PF05824.12 EMT53610.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.4 1 1 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) SpoVIF PF14069.6 EMT53611.1 - 9.5e-20 70.2 0.5 1.1e-19 69.9 0.5 1.1 1 0 0 1 1 1 1 Stage VI sporulation protein F DUF1002 PF06207.11 EMT53611.1 - 0.013 15.0 0.3 0.013 15.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DUF4942 PF13708.6 EMT53611.1 - 0.035 14.1 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) SPK PF04435.18 EMT53611.1 - 0.089 13.2 0.9 1.9 8.9 0.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF545) NAD_Gly3P_dh_N PF01210.23 EMT53612.1 - 1.6e-54 184.1 0.3 2.4e-54 183.6 0.3 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EMT53612.1 - 4.8e-52 176.0 0.1 7.5e-52 175.4 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus ApbA PF02558.16 EMT53612.1 - 7e-11 42.0 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EMT53612.1 - 7.2e-11 42.5 0.0 2.9e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EMT53612.1 - 2.5e-08 34.3 0.1 4.9e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EMT53612.1 - 3.1e-07 30.5 0.1 1.2e-06 28.5 0.0 2.0 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EMT53612.1 - 2.4e-05 24.0 0.0 0.00023 20.8 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rossmann-like PF10727.9 EMT53612.1 - 9e-05 22.3 0.3 0.00061 19.7 0.2 2.5 2 1 0 2 2 2 1 Rossmann-like domain IlvN PF07991.12 EMT53612.1 - 0.00053 19.6 0.0 0.0024 17.5 0.0 2.0 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain PDH PF02153.17 EMT53612.1 - 0.0032 16.5 0.1 0.0042 16.1 0.1 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase Pyr_redox PF00070.27 EMT53612.1 - 0.019 15.5 0.3 0.11 13.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMT53612.1 - 0.031 14.5 0.0 7.5 6.8 0.0 2.6 2 1 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 EMT53612.1 - 0.11 11.8 0.1 0.15 11.3 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT53612.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.20 EMT53612.1 - 0.16 12.1 0.0 0.5 10.4 0.0 2.0 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase G3P_acyltransf PF02660.15 EMT53613.1 - 4.7e-51 173.1 17.9 5.3e-51 172.9 17.9 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase MMR_HSR1 PF01926.23 EMT53614.1 - 3.7e-55 184.9 0.8 2.3e-26 92.1 0.2 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 EMT53614.1 - 1e-35 121.9 0.3 2.7e-35 120.5 0.2 1.8 2 0 0 2 2 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 EMT53614.1 - 1.4e-29 102.6 0.2 1.9e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EMT53614.1 - 8.4e-19 67.9 1.0 4.5e-08 32.9 0.3 5.1 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EMT53614.1 - 1.7e-14 54.2 1.6 0.0082 16.2 0.0 4.4 2 2 2 4 4 4 3 Dynamin family AIG1 PF04548.16 EMT53614.1 - 1.4e-13 50.6 0.2 8.6e-07 28.5 0.1 2.5 2 1 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 EMT53614.1 - 4.7e-10 39.6 1.0 0.024 14.5 0.0 4.0 4 0 0 4 4 4 3 RsgA GTPase Roc PF08477.13 EMT53614.1 - 4.3e-07 30.2 0.8 0.017 15.3 0.0 4.1 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EMT53614.1 - 1.2e-06 28.3 0.0 0.027 14.2 0.0 3.5 2 2 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EMT53614.1 - 5e-06 27.1 0.0 0.051 14.1 0.0 2.7 2 1 0 2 2 2 2 ABC transporter Nuc_deoxyri_tr2 PF15891.5 EMT53614.1 - 0.00015 22.1 0.8 0.64 10.4 0.0 3.0 2 1 1 3 3 3 2 Nucleoside 2-deoxyribosyltransferase like cobW PF02492.19 EMT53614.1 - 0.00032 20.3 1.2 0.024 14.2 0.2 2.8 2 2 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain SIS PF01380.22 EMT53614.1 - 0.00084 19.2 0.1 0.57 10.0 0.0 2.3 2 0 0 2 2 2 2 SIS domain Ras PF00071.22 EMT53614.1 - 0.00094 18.8 0.7 0.23 11.1 0.2 3.0 2 2 0 2 2 2 1 Ras family MeaB PF03308.16 EMT53614.1 - 0.0014 17.7 1.3 6.3 5.7 0.1 3.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 EMT53614.1 - 0.0017 18.8 0.3 3.4 8.1 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1_Xtn PF16897.5 EMT53614.1 - 0.0019 18.2 0.0 0.24 11.4 0.0 2.8 2 1 0 2 2 2 1 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 EMT53614.1 - 0.0026 18.3 0.1 1.1 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Nuc_deoxyrib_tr PF05014.15 EMT53614.1 - 0.0034 17.4 0.3 0.06 13.4 0.0 2.3 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase AAA_24 PF13479.6 EMT53614.1 - 0.007 16.1 0.0 4.2 7.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EMT53614.1 - 0.012 16.0 0.0 8 6.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase TniB PF05621.11 EMT53614.1 - 0.012 15.0 0.1 2.6 7.4 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein AAA_22 PF13401.6 EMT53614.1 - 0.014 15.6 0.1 18 5.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EMT53614.1 - 0.02 15.3 0.1 15 5.9 0.0 3.3 2 2 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 EMT53614.1 - 0.033 13.4 0.0 3.8 6.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain SRPRB PF09439.10 EMT53614.1 - 0.046 13.1 0.0 6.1 6.2 0.0 2.7 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 EMT53614.1 - 0.077 12.8 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EMT53614.1 - 0.14 11.9 0.1 11 5.6 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain DUF4062 PF13271.6 EMT53614.1 - 0.15 12.4 0.0 4 7.9 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4062) YIEGIA PF14045.6 EMT53616.1 - 5.6e-117 389.6 0.0 6.4e-117 389.4 0.0 1.0 1 0 0 1 1 1 1 YIEGIA protein Wzz PF02706.15 EMT53616.1 - 0.35 11.2 1.1 0.8 10.1 0.0 2.1 2 0 0 2 2 2 0 Chain length determinant protein FMN_dh PF01070.18 EMT53618.1 - 8.2e-20 71.1 0.9 1.1e-19 70.7 0.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EMT53618.1 - 1.9e-08 33.7 6.3 5.4e-06 25.6 3.7 3.0 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EMT53618.1 - 9.8e-07 28.2 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EMT53618.1 - 0.0022 17.3 1.7 0.003 16.8 0.1 1.9 2 1 1 3 3 3 1 Dihydroorotate dehydrogenase NMO PF03060.15 EMT53618.1 - 0.0078 15.6 0.1 0.026 13.9 0.1 1.8 2 0 0 2 2 2 1 Nitronate monooxygenase S1 PF00575.23 EMT53619.1 - 3.6e-80 264.3 37.0 3.1e-27 94.7 2.4 4.1 4 0 0 4 4 4 4 S1 RNA binding domain DUF2110 PF09883.9 EMT53619.1 - 2.2e-05 24.2 7.2 0.29 10.7 0.2 4.0 1 1 3 4 4 4 3 Uncharacterized protein conserved in archaea (DUF2110) S1_2 PF13509.6 EMT53619.1 - 8.6e-05 22.5 12.5 0.053 13.6 0.3 5.6 5 3 0 5 5 5 2 S1 domain PCB_OB PF17092.5 EMT53619.1 - 0.00012 22.7 15.2 0.083 13.7 0.3 4.6 1 1 3 4 4 4 2 Penicillin-binding protein OB-like domain DUF1421 PF07223.11 EMT53619.1 - 0.0062 16.3 1.7 39 4.2 0.0 4.4 4 0 0 4 4 4 0 UBA-like domain (DUF1421) SH3_2 PF07653.17 EMT53619.1 - 0.01 15.5 5.7 3.3 7.4 0.1 5.1 6 0 0 6 6 6 0 Variant SH3 domain SAM_KSR1 PF13543.6 EMT53619.1 - 0.012 15.8 0.1 0.031 14.4 0.1 1.6 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Cofilin_ADF PF00241.20 EMT53619.1 - 0.17 11.7 4.9 4.2 7.2 0.2 3.2 3 0 0 3 3 3 0 Cofilin/tropomyosin-type actin-binding protein RsgI_N PF12791.7 EMT53619.1 - 0.23 11.4 4.9 1 9.3 0.1 3.2 3 0 0 3 3 3 0 Anti-sigma factor N-terminus RuvA_N PF01330.21 EMT53619.1 - 0.46 10.6 3.6 2.3 8.4 0.1 3.5 4 0 0 4 4 4 0 RuvA N terminal domain EXOSC1 PF10447.9 EMT53619.1 - 2 9.1 14.6 0.22 12.1 0.8 4.3 3 2 0 4 4 4 0 Exosome component EXOSC1/CSL4 Acyltransferase PF01553.21 EMT53620.1 - 3.4e-26 91.5 0.0 4.7e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Lip_A_acyltrans PF03279.13 EMT53620.1 - 0.19 10.9 0.0 0.55 9.3 0.0 1.7 1 1 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Cytidylate_kin PF02224.18 EMT53621.1 - 3.1e-81 272.1 3.8 3.5e-81 272.0 3.8 1.0 1 0 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 EMT53621.1 - 1.6e-12 47.9 1.5 3.5e-12 46.8 1.5 1.5 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 EMT53621.1 - 4.3e-09 37.0 0.1 2.1e-08 34.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EMT53621.1 - 3.8e-08 33.8 1.1 1.2e-06 28.9 0.6 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMT53621.1 - 1.7e-06 28.3 2.2 8.9e-05 22.7 2.2 2.7 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EMT53621.1 - 6.8e-06 26.3 3.6 0.00015 21.9 0.0 2.9 1 1 1 3 3 3 1 Shikimate kinase AAA_28 PF13521.6 EMT53621.1 - 4.3e-05 23.8 1.7 0.0027 18.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain CoaE PF01121.20 EMT53621.1 - 7.8e-05 22.4 0.1 0.00017 21.3 0.0 1.6 1 1 0 1 1 1 1 Dephospho-CoA kinase ADK PF00406.22 EMT53621.1 - 0.00084 19.5 0.0 0.0019 18.3 0.0 1.6 1 1 0 1 1 1 1 Adenylate kinase ABC_tran PF00005.27 EMT53621.1 - 0.0012 19.4 0.3 0.0037 17.8 0.3 2.0 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EMT53621.1 - 0.002 18.4 0.0 0.0038 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 EMT53621.1 - 0.0022 17.9 0.1 0.0038 17.1 0.1 1.7 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA PF00004.29 EMT53621.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 EMT53621.1 - 0.023 14.4 0.3 0.17 11.6 0.3 2.2 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EMT53621.1 - 0.045 13.5 0.1 0.11 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMT53621.1 - 0.046 14.1 2.7 0.25 11.7 2.7 2.1 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 EMT53621.1 - 0.047 13.6 0.2 0.89 9.4 0.0 2.4 2 1 0 2 2 2 0 Adenylylsulphate kinase Rad17 PF03215.15 EMT53621.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 EMT53621.1 - 0.053 13.4 0.1 0.13 12.2 0.1 1.8 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EMT53621.1 - 0.08 12.7 4.0 0.21 11.3 0.7 2.6 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EMT53621.1 - 0.09 12.7 0.1 0.34 10.8 0.0 2.0 2 1 0 2 2 2 0 NTPase RNA_helicase PF00910.22 EMT53621.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.6 1 1 0 1 1 1 0 RNA helicase Efg1 PF10153.9 EMT53621.1 - 0.14 12.5 2.4 0.15 12.4 0.4 2.0 2 0 0 2 2 2 0 rRNA-processing protein Efg1 YcgR_2 PF12945.7 EMT53623.1 - 1.2e-18 67.0 0.0 5.1e-18 65.0 0.0 2.0 2 0 0 2 2 2 1 Flagellar protein YcgR PilZ PF07238.14 EMT53623.1 - 3.5e-13 49.7 0.0 4.2e-12 46.3 0.0 2.1 2 1 1 3 3 3 1 PilZ domain YPEB PF14620.6 EMT53624.1 - 7.6e-136 453.2 5.0 7.6e-136 453.2 5.0 1.6 1 1 1 2 2 2 1 YpeB sporulation PepSY PF03413.19 EMT53624.1 - 1.7e-08 34.9 0.2 0.0021 18.6 0.0 3.3 3 0 0 3 3 3 2 Peptidase propeptide and YPEB domain Inhibitor_I69 PF13734.6 EMT53624.1 - 0.057 13.9 0.0 2 8.9 0.0 2.8 2 0 0 2 2 2 0 Spi protease inhibitor DUF1465 PF07323.12 EMT53624.1 - 0.49 10.2 4.4 1.8 8.4 0.8 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1465) Hydrolase_2 PF07486.12 EMT53625.1 - 8.8e-30 103.6 0.0 1.9e-29 102.6 0.0 1.5 2 0 0 2 2 2 1 Cell Wall Hydrolase WW PF00397.26 EMT53625.1 - 0.00035 20.6 0.4 0.0007 19.6 0.4 1.5 1 0 0 1 1 1 1 WW domain SpoIIIAH PF12685.7 EMT53625.1 - 0.026 14.3 0.1 0.031 14.1 0.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein PrsW-protease PF13367.6 EMT53626.1 - 3.2e-36 124.6 14.4 4.9e-36 124.0 14.4 1.2 1 0 0 1 1 1 1 PrsW family intramembrane metalloprotease Pet100 PF09803.9 EMT53626.1 - 0.0022 18.5 0.5 3.8 8.1 0.3 2.6 2 0 0 2 2 2 2 Pet100 Asparaginase PF00710.20 EMT53627.1 - 4.7e-60 202.4 0.1 6.7e-60 201.9 0.1 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EMT53627.1 - 3.8e-29 101.2 0.0 2.9e-28 98.4 0.0 2.2 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain ELFV_dehydrog PF00208.21 EMT53628.1 - 1.4e-77 260.7 0.4 2.6e-77 259.8 0.4 1.4 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EMT53628.1 - 1.1e-54 183.7 0.0 2e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 EMT53628.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EMT53628.1 - 0.14 12.6 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding PIG-L PF02585.17 EMT53629.1 - 1.2e-32 113.3 0.0 1.8e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase MecA PF05389.12 EMT53630.1 - 6.4e-42 143.7 3.1 8.3e-23 81.2 0.1 2.0 1 1 1 2 2 2 2 Negative regulator of genetic competence (MecA) Chal_sti_synt_C PF02797.15 EMT53630.1 - 0.038 14.0 0.1 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain Hemopexin PF00045.19 EMT53630.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Hemopexin Fumarate_red_C PF02300.17 EMT53631.1 - 0.34 11.0 3.0 2.1 8.5 2.9 2.3 1 1 1 2 2 2 0 Fumarate reductase subunit C DUF962 PF06127.11 EMT53631.1 - 0.36 10.9 2.3 0.17 12.0 0.3 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Pyr_redox_2 PF07992.14 EMT53632.1 - 1.7e-24 86.6 0.0 2.9e-23 82.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT53632.1 - 8.1e-14 51.6 0.0 2.8e-09 36.7 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMT53632.1 - 2.6e-07 30.6 5.9 0.0012 18.5 2.6 2.8 1 1 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EMT53632.1 - 3.8e-06 25.9 0.1 0.0018 17.0 0.3 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EMT53632.1 - 6.1e-05 22.3 3.5 0.00028 20.1 2.0 2.2 2 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EMT53632.1 - 0.0001 22.3 1.5 1.2 9.2 0.1 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMT53632.1 - 0.00087 19.5 1.7 0.0019 18.4 1.7 1.6 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EMT53632.1 - 0.001 18.2 1.7 0.007 15.5 0.5 2.2 1 1 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EMT53632.1 - 0.0019 17.2 1.0 0.0025 16.7 0.2 1.6 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 EMT53632.1 - 0.011 15.1 1.0 0.011 15.1 1.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMT53632.1 - 0.013 14.8 0.2 0.026 13.8 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EMT53632.1 - 0.12 13.0 0.5 0.97 10.0 0.2 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMT53632.1 - 0.13 11.3 0.9 1.1 8.2 0.3 2.2 1 1 0 2 2 2 0 Lycopene cyclase protein LysM PF01476.20 EMT53633.1 - 1.9e-08 34.3 0.0 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 LysM domain OapA PF04225.12 EMT53633.1 - 0.12 12.5 0.2 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Opacity-associated protein A LysM-like domain TFIIA PF03153.13 EMT53633.1 - 0.9 9.5 17.0 1 9.3 17.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 EMT53633.1 - 1.4 8.1 10.2 1.5 8.0 10.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RR_TM4-6 PF06459.12 EMT53633.1 - 1.9 8.3 8.5 2.8 7.7 8.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EMT53633.1 - 4.5 5.9 9.1 6.1 5.5 9.1 1.3 1 0 0 1 1 1 0 Presenilin CPBP PF02517.16 EMT53634.1 - 3.6e-13 49.7 3.4 3.6e-13 49.7 3.4 2.0 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DEAD PF00270.29 EMT53635.1 - 1.9e-19 70.1 0.0 6.3e-19 68.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMT53635.1 - 3.8e-19 69.1 0.0 7e-16 58.6 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EMT53635.1 - 9.6e-07 29.4 0.5 2.7e-06 28.0 0.5 1.8 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 EMT53635.1 - 0.00013 22.0 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_40 PF14493.6 EMT53636.1 - 8.1e-21 74.3 0.0 3.9e-20 72.1 0.0 2.1 2 1 1 3 3 3 1 Helix-turn-helix domain GerE PF00196.19 EMT53636.1 - 0.027 14.0 0.0 0.13 11.9 0.0 2.2 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EMT53636.1 - 0.032 13.9 0.5 0.22 11.2 0.0 2.7 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_20 PF12840.7 EMT53636.1 - 0.04 14.0 0.0 17 5.5 0.0 3.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_10 PF04967.12 EMT53636.1 - 0.072 12.9 0.1 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain UPF0154 PF03672.13 EMT53637.1 - 0.068 13.2 0.7 0.17 11.9 0.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Fer4_13 PF13370.6 EMT53638.1 - 1.1e-21 77.1 2.9 1.3e-21 76.9 2.9 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EMT53638.1 - 2.1e-14 54.0 3.4 2.3e-14 53.9 3.4 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4 PF00037.27 EMT53638.1 - 0.00017 21.2 3.1 0.0028 17.4 1.4 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 EMT53638.1 - 0.0024 17.9 1.0 0.0024 17.9 1.0 1.9 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_19 PF06902.11 EMT53638.1 - 0.0028 17.7 0.1 0.0043 17.1 0.1 1.4 1 1 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4_21 PF14697.6 EMT53638.1 - 0.016 15.3 0.4 0.033 14.3 0.1 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 EMT53638.1 - 0.025 14.7 1.6 0.057 13.5 0.4 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain DHH PF01368.20 EMT53639.1 - 2.6e-31 107.8 0.1 4.9e-31 107.0 0.1 1.5 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.14 EMT53639.1 - 1.5e-20 73.8 0.5 3e-20 72.9 0.5 1.5 1 0 0 1 1 1 1 DHHA2 domain Aminotran_5 PF00266.19 EMT53640.1 - 9.9e-43 146.5 0.0 1.2e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMT53640.1 - 3.7e-05 23.1 0.0 6.7e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMT53640.1 - 0.00022 19.9 0.0 0.00032 19.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EMT53640.1 - 0.00046 19.6 0.0 0.0011 18.4 0.0 1.5 1 1 1 2 2 2 1 Beta-eliminating lyase DUF2656 PF10847.8 EMT53640.1 - 0.029 14.5 0.0 0.96 9.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2656) 2-Hacid_dh_C PF02826.19 EMT53641.1 - 3.8e-64 215.3 0.0 7.8e-64 214.3 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMT53641.1 - 3.7e-37 127.0 1.0 7e-36 122.8 0.4 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 EMT53641.1 - 7.5e-10 38.4 0.0 2.3e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 EMT53641.1 - 2.7e-05 24.4 0.1 6.3e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EMT53641.1 - 6.3e-05 22.6 0.6 0.00098 18.7 0.0 2.6 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ACT_4 PF13291.6 EMT53641.1 - 0.00018 22.0 0.4 0.00074 20.1 0.0 2.2 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.6 EMT53641.1 - 0.057 13.3 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 ACT domain F420_oxidored PF03807.17 EMT53641.1 - 0.079 13.6 0.5 0.34 11.5 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CitMHS PF03600.16 EMT53642.1 - 7.7e-56 189.5 34.6 7.7e-56 189.5 34.6 1.9 1 1 1 2 2 2 1 Citrate transporter ArsB PF02040.15 EMT53642.1 - 1.5e-19 70.7 32.3 1.9e-19 70.3 32.3 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein Na_sulph_symp PF00939.19 EMT53642.1 - 5e-16 58.8 36.0 3.3e-07 29.7 8.6 2.9 1 1 2 3 3 3 3 Sodium:sulfate symporter transmembrane region DcuA_DcuB PF03605.14 EMT53642.1 - 0.00029 19.9 17.4 0.00029 19.9 17.4 2.2 2 1 0 2 2 2 1 Anaerobic c4-dicarboxylate membrane transporter DUF3087 PF11286.8 EMT53642.1 - 7.8 5.9 9.2 0.14 11.6 0.9 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3087) Hydrolase_like PF13242.6 EMT53644.1 - 3.8e-13 49.3 0.0 1.5e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 EMT53644.1 - 8.6e-11 42.2 0.0 8.1e-08 32.5 0.0 3.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMT53644.1 - 1.1e-06 29.0 0.0 2.1e-05 24.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMT53644.1 - 0.11 12.2 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HATPase_c PF02518.26 EMT53645.1 - 1.3e-28 99.7 0.3 7.3e-28 97.3 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT53645.1 - 7.5e-20 70.7 0.7 3.2e-19 68.7 0.2 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HisK_sensor PF18698.1 EMT53645.1 - 1.3e-18 67.6 0.1 6.6e-18 65.3 0.0 2.2 2 1 0 2 2 2 1 Histidine kinase sensor domain HAMP PF00672.25 EMT53645.1 - 3.4e-16 59.4 0.0 9.8e-16 57.9 0.0 1.9 1 0 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.6 EMT53645.1 - 9.3e-06 25.5 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 EMT53645.1 - 0.00027 21.2 0.1 0.027 14.7 0.1 2.7 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 EMT53645.1 - 0.0045 17.0 0.0 0.039 13.9 0.0 2.5 2 0 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.6 EMT53645.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 GHKL domain DUF4064 PF13273.6 EMT53645.1 - 0.089 13.1 2.7 4.9 7.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) GAT PF03127.14 EMT53645.1 - 0.39 11.0 2.5 2.9 8.3 0.0 3.4 3 1 1 4 4 4 0 GAT domain DUF948 PF06103.11 EMT53645.1 - 0.43 10.9 5.8 3.8 7.8 0.0 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Response_reg PF00072.24 EMT53646.1 - 3.3e-32 111.0 0.1 5.6e-32 110.2 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT53646.1 - 1.4e-28 98.8 0.0 3.2e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal GerE PF00196.19 EMT53646.1 - 0.012 15.2 0.1 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Cytochrom_C_asm PF01578.20 EMT53647.1 - 2.4e-38 132.0 26.0 2.4e-38 132.0 22.0 2.7 2 1 0 2 2 2 1 Cytochrome C assembly protein TMEM192 PF14802.6 EMT53647.1 - 4.1 6.4 5.1 2 7.4 0.2 2.7 3 0 0 3 3 3 0 TMEM192 family ResB PF05140.14 EMT53648.1 - 1.2e-91 307.9 0.0 1.4e-88 297.8 0.0 2.0 1 1 0 1 1 1 1 ResB-like family CcmF_C PF16327.5 EMT53648.1 - 0.03 13.6 0.1 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal DZR PF12773.7 EMT53648.1 - 0.075 13.1 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf_C2H2_13 PF18508.1 EMT53648.1 - 0.14 11.8 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Zinc finger domain zinc_ribbon_2 PF13240.6 EMT53648.1 - 0.38 10.5 2.5 0.64 9.8 2.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain AhpC-TSA PF00578.21 EMT53649.1 - 2.8e-36 124.2 0.0 3.5e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMT53649.1 - 2.7e-27 95.3 0.0 3.2e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EMT53649.1 - 1.4e-13 51.0 0.0 2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 EMT53649.1 - 2e-08 34.1 0.1 2e-06 27.7 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EMT53649.1 - 2.9e-07 30.9 0.0 4.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain GSHPx PF00255.19 EMT53649.1 - 4.1e-05 23.1 0.0 7.7e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione peroxidase SCO1-SenC PF02630.14 EMT53649.1 - 0.0032 17.4 0.0 0.012 15.5 0.0 1.8 1 1 1 2 2 2 1 SCO1/SenC AhpC-TSA_2 PF13911.6 EMT53649.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme T4_deiodinase PF00837.17 EMT53649.1 - 0.02 14.2 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase PsbN PF02468.15 EMT53649.1 - 0.064 13.1 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) PseudoU_synth_2 PF00849.22 EMT53650.1 - 3.4e-24 85.7 0.0 5.9e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EMT53650.1 - 8.6e-16 57.4 2.4 1.8e-15 56.4 0.7 2.3 1 1 1 2 2 2 1 S4 domain MatE PF01554.18 EMT53651.1 - 7.3e-40 136.3 42.8 2.7e-25 88.9 14.4 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EMT53651.1 - 2.6e-07 30.8 11.1 2.6e-07 30.8 11.1 5.5 2 2 3 5 5 5 2 Polysaccharide biosynthesis C-terminal domain MarR PF01047.22 EMT53652.1 - 7.9e-13 48.1 0.2 1.4e-12 47.3 0.2 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EMT53652.1 - 1.6e-10 40.7 0.0 3e-10 39.8 0.0 1.5 2 0 0 2 2 1 1 MarR family HTH_27 PF13463.6 EMT53652.1 - 1.3e-09 38.4 0.0 3.1e-09 37.2 0.0 1.6 2 0 0 2 2 1 1 Winged helix DNA-binding domain HTH_11 PF08279.12 EMT53652.1 - 9.3e-06 25.5 0.2 1.9e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 EMT53652.1 - 1.2e-05 24.8 0.5 2.9e-05 23.5 0.5 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding B-block_TFIIIC PF04182.12 EMT53652.1 - 7.5e-05 22.8 1.2 0.00052 20.1 0.1 2.2 1 1 1 2 2 2 1 B-block binding subunit of TFIIIC Rrf2 PF02082.20 EMT53652.1 - 0.00021 21.6 0.7 0.00036 20.8 0.2 1.7 2 0 0 2 2 1 1 Transcriptional regulator TrmB PF01978.19 EMT53652.1 - 0.00025 20.9 0.0 0.00049 19.9 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB GntR PF00392.21 EMT53652.1 - 0.00035 20.2 0.8 0.00093 18.8 0.0 2.1 3 0 0 3 3 2 1 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 EMT53652.1 - 0.00035 20.7 0.2 0.0011 19.2 0.1 2.0 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HxlR PF01638.17 EMT53652.1 - 0.00044 20.0 0.3 0.0013 18.5 0.1 1.9 1 1 1 2 2 2 1 HxlR-like helix-turn-helix HTH_Crp_2 PF13545.6 EMT53652.1 - 0.00047 20.1 0.8 0.0016 18.4 0.1 2.1 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 EMT53652.1 - 0.00061 19.9 0.1 0.0014 18.8 0.1 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_10 PF04967.12 EMT53652.1 - 0.00066 19.4 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 HTH DNA binding domain HTH_5 PF01022.20 EMT53652.1 - 0.00083 19.2 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_45 PF14947.6 EMT53652.1 - 0.0047 16.9 0.2 0.011 15.7 0.1 1.6 1 1 0 1 1 1 1 Winged helix-turn-helix UPF0122 PF04297.14 EMT53652.1 - 0.0055 16.9 6.7 0.009 16.2 4.6 2.3 1 1 1 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_Tnp_4 PF13613.6 EMT53652.1 - 0.0061 16.3 0.0 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease HTH_WhiA PF02650.14 EMT53652.1 - 0.013 15.8 1.7 0.04 14.2 0.5 2.1 2 0 0 2 2 2 0 WhiA C-terminal HTH domain Sigma70_r4 PF04545.16 EMT53652.1 - 0.016 14.7 0.1 0.036 13.6 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 CENP-B_N PF04218.13 EMT53652.1 - 0.018 14.6 0.3 0.036 13.7 0.3 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_1 PF00126.27 EMT53652.1 - 0.025 14.5 0.0 0.064 13.2 0.0 1.7 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family TFIIE_alpha PF02002.17 EMT53652.1 - 0.026 14.4 2.6 0.27 11.1 0.1 2.3 1 1 0 2 2 2 0 TFIIE alpha subunit MRP-L20 PF12824.7 EMT53652.1 - 0.029 14.6 0.3 0.036 14.2 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 HTH_IclR PF09339.10 EMT53652.1 - 0.04 13.7 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_20 PF12840.7 EMT53652.1 - 0.055 13.5 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_DeoR PF08220.12 EMT53652.1 - 0.072 12.9 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HemN_C PF06969.16 EMT53652.1 - 0.076 13.1 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 HemN C-terminal domain Mannosyl_trans2 PF04188.13 EMT53652.1 - 0.13 11.6 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) Mga PF05043.13 EMT53652.1 - 0.14 12.7 4.1 0.15 12.6 1.6 2.2 2 1 1 3 3 3 0 Mga helix-turn-helix domain HTH_28 PF13518.6 EMT53652.1 - 0.18 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Gate PF07670.14 EMT53653.1 - 2.6e-06 27.7 0.9 2.6e-06 27.7 0.9 1.7 2 0 0 2 2 2 1 Nucleoside recognition Gate PF07670.14 EMT53654.1 - 1e-09 38.6 0.5 1e-09 38.6 0.5 2.2 2 1 1 3 3 3 1 Nucleoside recognition DUF2545 PF10810.8 EMT53654.1 - 0.21 11.7 2.9 1.1 9.5 2.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2545) MHYT PF03707.16 EMT53654.1 - 0.41 10.9 0.0 0.41 10.9 0.0 2.7 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat MscS_TM PF12794.7 EMT53654.1 - 0.79 8.5 4.5 0.19 10.6 0.3 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Peptidase_S11 PF00768.20 EMT53655.1 - 4e-64 216.3 1.3 5.3e-64 215.9 1.3 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 EMT53655.1 - 1.6e-06 28.3 0.0 3.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 EMT53655.1 - 3.1e-06 26.9 0.0 4.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 EMT53655.1 - 0.0057 15.9 0.1 0.75 9.0 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase Peptidase_S13 PF02113.15 EMT53655.1 - 0.012 14.4 1.3 0.023 13.5 0.4 1.8 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family SMC_ScpB PF04079.16 EMT53656.1 - 4.8e-56 188.8 0.1 5.7e-56 188.6 0.1 1.0 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB SMC_ScpA PF02616.14 EMT53657.1 - 7.7e-45 153.7 9.1 9.2e-45 153.4 9.1 1.1 1 0 0 1 1 1 1 Segregation and condensation protein ScpA Rad21_Rec8 PF04824.16 EMT53657.1 - 0.003 16.8 0.0 0.006 15.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein HxlR PF01638.17 EMT53657.1 - 0.14 12.0 0.8 0.35 10.7 0.4 2.0 1 1 1 2 2 2 0 HxlR-like helix-turn-helix Peptidase_M50 PF02163.22 EMT53658.1 - 2.1e-10 40.3 12.7 7.8e-06 25.3 0.5 2.8 1 1 1 2 2 2 2 Peptidase family M50 AzlD PF05437.12 EMT53659.1 - 1.6e-14 53.8 7.3 1.9e-14 53.6 7.3 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein (AzlD) AzlC PF03591.14 EMT53660.1 - 1e-34 119.9 12.6 1e-34 119.9 12.6 2.0 2 0 0 2 2 2 1 AzlC protein tRNA-synt_2c PF01411.19 EMT53661.1 - 4.1e-14 52.0 0.7 6.2e-14 51.4 0.7 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EMT53661.1 - 9.2e-13 48.1 0.3 1.7e-12 47.2 0.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TrmB PF01978.19 EMT53662.1 - 3.8e-19 68.3 0.1 7.4e-19 67.4 0.1 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF5340 PF17275.2 EMT53662.1 - 0.0024 17.9 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5340) Regulator_TrmB PF11495.8 EMT53662.1 - 0.0033 16.6 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB RHH_3 PF12651.7 EMT53662.1 - 0.065 13.2 0.1 1.1 9.3 0.0 3.0 2 0 0 2 2 2 0 Ribbon-helix-helix domain HTH_11 PF08279.12 EMT53662.1 - 0.077 12.9 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 HTH domain DUF742 PF05331.11 EMT53662.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Pro_isomerase PF00160.21 EMT53663.1 - 1e-45 155.8 0.2 1.1e-45 155.7 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EAL PF00563.20 EMT53664.1 - 2.6e-52 177.7 0.0 4e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 EMT53664.1 - 2.1e-22 79.6 0.1 1.4e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 Diguanylate cyclase, GGDEF domain CBS PF00571.28 EMT53664.1 - 6.8e-14 52.0 1.5 4.2e-08 33.5 0.1 3.2 3 0 0 3 3 3 2 CBS domain Orn_Arg_deC_N PF02784.16 EMT53665.1 - 8.8e-68 228.3 0.0 1.3e-67 227.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EMT53665.1 - 2.8e-19 69.1 0.0 3.6e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 EMT53665.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain GerA PF03323.13 EMT53666.1 - 2.6e-151 504.3 2.0 3e-151 504.1 2.0 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein SpoVAE PF14097.6 EMT53667.1 - 8.8e-79 263.3 2.1 1e-78 263.1 2.1 1.0 1 0 0 1 1 1 1 Stage V sporulation protein AE1 Big_1 PF02369.16 EMT53667.1 - 0.045 13.8 0.4 0.27 11.3 0.2 2.3 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) Toprim_4 PF13662.6 EMT53667.1 - 0.087 13.3 0.1 1.9 9.0 0.0 2.2 1 1 1 2 2 2 0 Toprim domain SpoVAC_SpoVAEB PF03862.13 EMT53668.1 - 1.6e-40 137.9 10.9 1.8e-40 137.8 10.9 1.0 1 0 0 1 1 1 1 SpoVAC/SpoVAEB sporulation membrane protein SpoVAD PF07451.11 EMT53669.1 - 8.8e-154 511.1 0.2 9.9e-154 510.9 0.2 1.0 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 EMT53669.1 - 0.0032 17.1 3.2 0.8 9.2 0.1 2.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 EMT53669.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EMT53669.1 - 0.31 10.9 8.4 11 6.0 4.9 3.1 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAC_SpoVAEB PF03862.13 EMT53670.1 - 9e-40 135.5 10.1 1.1e-39 135.2 10.1 1.1 1 0 0 1 1 1 1 SpoVAC/SpoVAEB sporulation membrane protein DUF3040 PF11239.8 EMT53670.1 - 2.8 8.3 0.0 2.8 8.3 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3040) SpoVAB PF13782.6 EMT53671.1 - 8.8e-34 116.1 3.5 8.8e-34 116.1 3.5 1.9 2 0 0 2 2 2 1 Stage V sporulation protein AB Kinocilin PF15033.6 EMT53671.1 - 0.1 12.2 0.5 0.18 11.5 0.5 1.5 1 0 0 1 1 1 0 Kinocilin protein CAAD PF14159.6 EMT53671.1 - 3.8 7.4 7.4 0.54 10.1 0.3 2.5 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SporV_AA PF12164.8 EMT53672.1 - 4.9e-18 65.3 0.0 8.8e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AA DUF2603 PF10788.9 EMT53672.1 - 0.03 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) TMEMspv1-c74-12 PF11044.8 EMT53672.1 - 0.065 13.2 3.3 0.87 9.6 0.3 2.7 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Sigma70_r3 PF04539.16 EMT53673.1 - 2.2e-18 66.1 0.5 4.4e-15 55.5 0.1 2.5 2 0 0 2 2 2 2 Sigma-70 region 3 Sigma70_r2 PF04542.14 EMT53673.1 - 3.7e-18 65.0 0.0 8.3e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EMT53673.1 - 2.1e-17 62.3 6.2 1.5e-15 56.5 2.7 2.8 2 1 1 3 3 3 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EMT53673.1 - 3e-08 33.2 1.1 3e-08 33.2 1.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_3 PF01381.22 EMT53673.1 - 1.1e-05 25.4 0.3 0.00073 19.5 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix KORA PF16509.5 EMT53673.1 - 2.8e-05 24.3 1.0 6.4e-05 23.2 0.4 1.9 2 0 0 2 2 1 1 TrfB plasmid transcriptional repressor HTH_23 PF13384.6 EMT53673.1 - 0.00018 21.2 1.3 0.0025 17.5 0.6 2.6 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 EMT53673.1 - 0.00057 19.7 0.2 0.036 14.0 0.1 2.6 2 0 0 2 2 2 1 MarR family HTH_28 PF13518.6 EMT53673.1 - 0.00063 19.8 0.3 0.17 12.0 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 EMT53673.1 - 0.00081 19.3 0.4 0.99 9.3 0.0 2.3 2 0 0 2 2 2 2 ECF sigma factor HTH_31 PF13560.6 EMT53673.1 - 0.0009 19.5 0.2 0.014 15.8 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 EMT53673.1 - 0.001 18.6 1.5 0.67 9.6 0.1 4.1 3 1 1 4 4 4 1 Winged helix-turn-helix DNA-binding HTH_37 PF13744.6 EMT53673.1 - 0.002 18.1 0.2 0.0066 16.4 0.1 1.9 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EMT53673.1 - 0.0068 15.8 0.1 3 7.3 0.0 3.1 2 1 1 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 HTH_Crp_2 PF13545.6 EMT53673.1 - 0.0092 15.9 0.5 0.47 10.5 0.2 2.8 2 2 1 3 3 3 1 Crp-like helix-turn-helix domain Trp_repressor PF01371.19 EMT53673.1 - 0.0097 16.0 0.7 0.024 14.7 0.7 1.7 1 0 0 1 1 1 1 Trp repressor protein HTH_AsnC-type PF13404.6 EMT53673.1 - 0.011 15.6 0.8 4.7 7.1 0.0 2.9 3 0 0 3 3 2 0 AsnC-type helix-turn-helix domain HTH_10 PF04967.12 EMT53673.1 - 0.014 15.2 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 HTH DNA binding domain YdaS_antitoxin PF15943.5 EMT53673.1 - 0.016 15.0 0.3 1 9.3 0.0 2.8 3 0 0 3 3 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT P22_Cro PF14549.6 EMT53673.1 - 0.017 15.0 0.1 21 5.0 0.0 3.2 3 0 0 3 3 3 0 DNA-binding transcriptional regulator Cro HTH_8 PF02954.19 EMT53673.1 - 0.019 14.7 0.0 0.63 9.9 0.0 2.8 2 1 1 3 3 3 0 Bacterial regulatory protein, Fis family HTH_19 PF12844.7 EMT53673.1 - 0.028 14.4 0.2 0.52 10.4 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.6 EMT53673.1 - 0.043 14.3 0.0 0.38 11.2 0.1 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain MerR PF00376.23 EMT53673.1 - 0.064 13.0 5.2 0.85 9.4 0.1 3.0 3 0 0 3 3 3 0 MerR family regulatory protein DUF134 PF02001.16 EMT53673.1 - 0.085 13.4 0.1 0.22 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_17 PF12728.7 EMT53673.1 - 0.14 12.3 0.5 2.9 8.1 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain HATPase_c_2 PF13581.6 EMT53674.1 - 2.3e-25 89.0 0.2 2.6e-25 88.8 0.2 1.0 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 EMT53674.1 - 1.6e-11 44.7 0.3 2.2e-11 44.3 0.3 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMT53674.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pcc1 PF09341.10 EMT53674.1 - 0.057 13.6 1.4 0.68 10.1 0.1 2.7 3 0 0 3 3 3 0 Transcription factor Pcc1 HATPase_c_4 PF13749.6 EMT53674.1 - 0.092 12.9 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal STAS PF01740.21 EMT53675.1 - 1.4e-24 86.0 0.1 1.6e-24 85.8 0.1 1.0 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EMT53675.1 - 4.2e-12 46.2 0.0 6.1e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 STAS domain Peptidase_S11 PF00768.20 EMT53676.1 - 3.8e-82 275.3 0.9 5.4e-82 274.9 0.9 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 EMT53676.1 - 7.6e-16 58.1 0.2 1.5e-15 57.2 0.2 1.5 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 EMT53676.1 - 5e-15 55.7 0.2 1.1e-14 54.6 0.1 1.6 2 0 0 2 2 2 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 EMT53676.1 - 0.0021 17.4 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S13 PF02113.15 EMT53676.1 - 0.011 14.6 0.1 0.018 13.8 0.1 1.3 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family MCPsignal PF00015.21 EMT53677.1 - 4.4e-43 147.1 48.7 2.7e-39 134.7 21.5 3.9 2 1 2 4 4 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 EMT53677.1 - 6.5e-23 81.8 0.5 6.5e-23 81.8 0.5 3.1 3 1 0 3 3 3 1 Cache domain HAMP PF00672.25 EMT53677.1 - 1.2e-10 41.6 0.3 3.7e-09 36.8 0.0 3.7 3 0 0 3 3 3 1 HAMP domain BLOC1_2 PF10046.9 EMT53677.1 - 4e-05 23.8 25.2 0.066 13.5 2.2 5.3 3 2 2 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EMT53677.1 - 0.00045 20.4 29.4 0.29 11.4 0.4 6.0 3 2 2 5 5 5 2 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EMT53677.1 - 0.002 18.1 29.8 0.12 12.4 2.5 5.7 3 2 2 5 5 5 3 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 EMT53677.1 - 0.008 16.5 15.7 0.34 11.3 1.5 5.3 1 1 3 4 4 4 1 Syntaxin-like protein DASH_Duo1 PF08651.10 EMT53677.1 - 0.014 15.2 18.9 0.24 11.2 0.4 5.3 5 1 0 5 5 5 0 DASH complex subunit Duo1 EMC3_TMCO1 PF01956.16 EMT53677.1 - 0.035 13.8 0.5 0.035 13.8 0.5 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like IFT57 PF10498.9 EMT53677.1 - 0.059 12.3 20.2 0.11 11.4 4.2 3.4 2 2 1 3 3 3 0 Intra-flagellar transport protein 57 dCache_2 PF08269.11 EMT53677.1 - 0.15 11.2 0.0 0.15 11.2 0.0 3.8 3 1 1 5 5 5 0 Cache domain RPW8 PF05659.11 EMT53677.1 - 0.19 11.4 7.0 1 9.1 0.2 3.9 2 2 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Lipoprotein_7 PF01540.16 EMT53677.1 - 0.35 10.1 22.5 0.2 10.9 18.7 2.3 2 1 0 2 2 2 0 Adhesin lipoprotein Serine_rich PF08824.10 EMT53677.1 - 0.4 10.7 11.7 0.37 10.8 0.5 3.8 3 1 0 3 3 3 0 Serine rich protein interaction domain Med9 PF07544.13 EMT53677.1 - 0.57 10.3 5.9 0.76 9.9 0.2 3.7 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 ISG65-75 PF11727.8 EMT53677.1 - 0.79 8.9 12.3 3 7.0 3.4 2.5 2 0 0 2 2 2 0 Invariant surface glycoprotein Fib_alpha PF08702.10 EMT53677.1 - 1.5 9.0 18.7 0.5 10.5 3.7 3.6 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family T7SS_ESX_EspC PF10824.8 EMT53677.1 - 1.5 9.3 28.0 2.9 8.4 0.4 6.2 1 1 2 5 5 5 0 Excreted virulence factor EspC, type VII ESX diderm MtrB PF05440.12 EMT53677.1 - 3.1 8.3 9.0 0.68 10.4 0.4 4.3 4 2 1 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B Laminin_II PF06009.12 EMT53677.1 - 3.1 7.8 34.1 1.1 9.3 4.1 4.8 2 1 3 5 5 5 0 Laminin Domain II Cor1 PF04803.12 EMT53677.1 - 4 7.7 8.1 1.6 8.9 0.4 3.7 3 2 1 4 4 4 0 Cor1/Xlr/Xmr conserved region Fzo_mitofusin PF04799.13 EMT53677.1 - 4.1 6.9 15.1 0.077 12.5 1.8 3.9 2 2 2 4 4 4 0 fzo-like conserved region Sec34 PF04136.15 EMT53677.1 - 6.6 6.6 14.1 1.4 8.8 0.5 4.4 2 2 3 5 5 5 0 Sec34-like family NPV_P10 PF05531.12 EMT53677.1 - 7.9 7.0 17.4 11 6.5 2.5 4.9 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein SKA1 PF07160.12 EMT53677.1 - 8.4 6.2 16.2 0.88 9.4 4.0 3.2 2 2 1 3 3 3 0 Spindle and kinetochore-associated protein 1 YtxH PF12732.7 EMT53677.1 - 9.3 6.9 17.8 5.6 7.6 0.2 5.5 3 2 2 5 5 5 0 YtxH-like protein ABC_tran PF00005.27 EMT53678.1 - 6.4e-33 114.2 0.0 8.8e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT53678.1 - 1.5e-18 67.1 0.4 2.6e-18 66.3 0.4 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EMT53678.1 - 0.0001 21.8 0.1 0.00018 21.0 0.1 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain PRK PF00485.18 EMT53678.1 - 0.00048 19.9 0.0 0.00069 19.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 EMT53678.1 - 0.008 16.5 0.2 0.022 15.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT53678.1 - 0.02 15.3 0.1 0.036 14.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 EMT53678.1 - 0.046 14.1 0.0 0.07 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EMT53678.1 - 0.06 13.1 0.1 13 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EMT53678.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 EMT53678.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EMT53678.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA PF00004.29 EMT53678.1 - 0.14 12.6 0.1 0.6 10.5 0.0 1.9 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 EMT53678.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 EMT53678.1 - 0.17 12.4 0.0 0.52 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EMT53679.1 - 1.9e-29 102.9 0.0 2.8e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT53679.1 - 3.1e-18 66.0 0.0 5.7e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT53679.1 - 5.9e-08 32.9 0.2 3.6e-07 30.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMT53679.1 - 3.8e-05 24.0 0.4 0.017 15.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EMT53679.1 - 7.3e-05 22.3 0.7 0.00028 20.4 0.7 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 EMT53679.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 EMT53679.1 - 0.0014 18.1 0.3 0.2 11.1 0.1 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 EMT53679.1 - 0.0059 17.0 0.1 0.0081 16.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EMT53679.1 - 0.006 17.0 1.2 0.26 11.7 1.2 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 EMT53679.1 - 0.012 14.6 0.1 0.09 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.22 EMT53679.1 - 0.018 15.5 0.0 0.051 14.0 0.0 1.8 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 EMT53679.1 - 0.019 14.7 0.2 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EMT53679.1 - 0.027 13.9 0.1 0.081 12.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_ATPase PF09818.9 EMT53679.1 - 0.04 12.7 2.2 0.057 12.2 0.3 2.0 2 1 0 2 2 2 0 Predicted ATPase of the ABC class ATP-synt_ab PF00006.25 EMT53679.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 EMT53679.1 - 0.065 12.9 0.4 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 EMT53679.1 - 0.072 13.0 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 EMT53679.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 EMT53679.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain PRK PF00485.18 EMT53679.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family BPD_transp_1 PF00528.22 EMT53680.1 - 2e-33 115.7 12.4 2e-33 115.7 12.4 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT53680.1 - 5.7e-15 55.0 0.4 5.7e-15 55.0 0.4 3.2 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 EMT53681.1 - 7.1e-41 140.0 14.5 7.1e-41 140.0 14.5 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 EMT53682.1 - 1.4e-93 313.8 11.2 1.4e-93 313.8 11.2 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle Inovirus_Gp2 PF11726.8 EMT53682.1 - 0.11 12.4 1.2 5.6 6.9 0.1 2.2 2 0 0 2 2 2 0 Inovirus Gp2 HTH_AsnC-type PF13404.6 EMT53683.1 - 8.3e-16 57.5 1.0 1.5e-15 56.7 1.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 EMT53683.1 - 2.2e-13 49.5 0.1 4.4e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 EMT53683.1 - 8.9e-09 35.2 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_Mga PF08280.11 EMT53683.1 - 6.7e-05 22.8 0.6 0.00017 21.5 0.1 1.9 2 1 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain Sigma70_r4 PF04545.16 EMT53683.1 - 0.00016 21.1 0.2 0.00041 19.8 0.2 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_11 PF08279.12 EMT53683.1 - 0.00056 19.8 0.0 0.00092 19.1 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_Tnp_ISL3 PF13542.6 EMT53683.1 - 0.00068 19.0 0.0 0.0015 17.9 0.0 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 EMT53683.1 - 0.0009 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 EMT53683.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 EMT53683.1 - 0.0045 16.7 0.1 0.0085 15.9 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain GerE PF00196.19 EMT53683.1 - 0.0083 15.6 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_5 PF01022.20 EMT53683.1 - 0.0098 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_DeoR PF08220.12 EMT53683.1 - 0.01 15.6 0.2 0.016 14.9 0.2 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain MarR PF01047.22 EMT53683.1 - 0.011 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 EMT53683.1 - 0.013 15.5 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.6 EMT53683.1 - 0.018 15.5 0.0 0.04 14.4 0.0 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 EMT53683.1 - 0.034 14.0 0.0 0.081 12.8 0.0 1.6 2 0 0 2 2 2 0 TFIIE alpha subunit HTH_29 PF13551.6 EMT53683.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_36 PF13730.6 EMT53683.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Dyp_perox PF04261.12 EMT53683.1 - 0.14 11.2 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Dyp-type peroxidase family PaaX PF07848.12 EMT53683.1 - 0.16 12.2 0.1 0.39 11.0 0.0 1.6 2 0 0 2 2 2 0 PaaX-like protein Glycos_transf_3 PF00591.21 EMT53684.1 - 5.6e-47 160.5 6.4 8.4e-47 159.9 6.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain PYNP_C PF07831.13 EMT53684.1 - 6.8e-25 86.5 0.8 2.1e-24 85.0 0.8 1.9 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain Glycos_trans_3N PF02885.17 EMT53684.1 - 2.3e-22 78.6 0.2 6.3e-22 77.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Ribosomal_S5 PF00333.20 EMT53684.1 - 0.012 15.6 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Biotin_lipoyl PF00364.22 EMT53684.1 - 0.019 14.8 0.2 0.86 9.5 0.0 2.7 2 0 0 2 2 2 0 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EMT53684.1 - 0.029 14.2 0.3 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 Biotin-lipoyl like DUF2254 PF10011.9 EMT53684.1 - 0.062 12.1 0.1 0.41 9.4 0.1 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2254) PNP_UDP_1 PF01048.20 EMT53685.1 - 1.5e-57 194.5 0.6 1.7e-57 194.4 0.6 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Metalloenzyme PF01676.18 EMT53686.1 - 5.3e-36 124.3 0.0 1.6e-35 122.7 0.0 1.7 1 1 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 EMT53686.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EMT53686.1 - 0.14 11.6 0.0 0.91 8.8 0.0 2.2 2 1 1 3 3 3 0 Sulfatase Phage_integrase PF00589.22 EMT53687.1 - 1.7e-54 184.2 0.1 2.3e-54 183.8 0.1 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 EMT53687.1 - 5.4e-19 68.3 1.4 4.1e-18 65.5 0.2 2.5 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 EMT53687.1 - 1.5e-10 41.4 0.9 7.2e-10 39.2 0.1 2.2 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 EMT53687.1 - 1.9e-05 24.9 0.1 0.037 14.4 0.0 2.8 2 1 1 3 3 3 2 Phage integrase SAM-like domain Phage_int_SAM_2 PF12834.7 EMT53687.1 - 0.018 15.7 0.1 0.21 12.3 0.0 2.6 2 1 0 2 2 2 0 Phage integrase, N-terminal Integrase_1 PF12835.7 EMT53687.1 - 0.12 12.5 1.5 0.22 11.6 0.4 2.0 2 1 0 2 2 2 0 Integrase DUF4227 PF14004.6 EMT53688.1 - 8.2e-22 77.0 0.0 9.2e-22 76.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4227) TssO PF17561.2 EMT53688.1 - 0.21 11.7 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO AlaDh_PNT_C PF01262.21 EMT53689.1 - 1.4e-83 279.4 4.0 1.8e-83 279.1 4.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EMT53689.1 - 2.4e-46 157.4 0.0 4.3e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Pyr_redox_2 PF07992.14 EMT53689.1 - 2e-05 24.0 0.2 5.3e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMT53689.1 - 3.4e-05 24.3 0.4 0.0001 22.8 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EMT53689.1 - 5e-05 22.7 0.1 0.00011 21.6 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EMT53689.1 - 0.00023 20.5 1.0 0.0045 16.3 0.2 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EMT53689.1 - 0.00082 19.3 0.2 0.0015 18.5 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EMT53689.1 - 0.0017 18.5 0.6 0.0048 17.1 0.3 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 EMT53689.1 - 0.0038 16.4 0.5 0.0053 15.9 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EMT53689.1 - 0.0061 17.0 0.1 0.012 16.1 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EMT53689.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 EMT53689.1 - 0.035 14.4 1.0 0.17 12.1 0.9 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMT53689.1 - 0.04 13.3 4.1 0.065 12.6 4.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase XdhC_C PF13478.6 EMT53689.1 - 0.11 13.0 0.1 0.28 11.7 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain DAO PF01266.24 EMT53689.1 - 0.52 9.8 8.3 0.13 11.8 4.7 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FUR PF01475.19 EMT53690.1 - 1.6e-37 128.3 0.7 2.1e-37 127.9 0.7 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family TF_Zn_Ribbon PF08271.12 EMT53690.1 - 0.054 13.0 0.3 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding LIM PF00412.22 EMT53690.1 - 1.1 9.5 5.7 0.57 10.5 2.0 2.2 1 1 0 2 2 2 0 LIM domain SpoIIM PF01944.17 EMT53691.1 - 5e-24 85.1 19.0 6.1e-24 84.8 19.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein M Abhydrolase_9_N PF15420.6 EMT53691.1 - 3.6 7.5 10.8 0.71 9.8 7.6 1.6 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus PHP_C PF13263.6 EMT53692.1 - 2.8e-07 30.2 0.0 1.3e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 PHP-associated HHH_5 PF14520.6 EMT53692.1 - 0.0044 17.6 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain IMS_HHH PF11798.8 EMT53692.1 - 0.0048 17.2 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif HHH_2 PF12826.7 EMT53692.1 - 0.055 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HypA PF01155.19 EMT53692.1 - 0.34 10.9 1.4 0.78 9.8 1.4 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin_2 PF18073.1 EMT53692.1 - 6.1 6.7 7.5 16 5.3 7.5 1.7 1 0 0 1 1 1 0 Rubredoxin metal binding domain NUDIX PF00293.28 EMT53693.1 - 2.1e-20 73.1 0.3 2.8e-20 72.7 0.3 1.2 1 0 0 1 1 1 1 NUDIX domain DUF3866 PF12982.7 EMT53694.1 - 1.1e-110 369.8 0.0 1.2e-110 369.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3866) Peptidase_M20 PF01546.28 EMT53695.1 - 1.9e-24 86.5 0.5 1.9e-24 86.5 0.5 1.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EMT53695.1 - 1.3e-15 57.6 0.0 9e-14 51.6 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M28 M20_dimer PF07687.14 EMT53695.1 - 3.4e-14 52.7 0.3 1e-13 51.2 0.2 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 EMT53695.1 - 9.2e-14 51.1 0.0 9e-07 28.2 0.0 3.3 3 0 0 3 3 3 3 M42 glutamyl aminopeptidase Carboxyl_trans PF01039.22 EMT53696.1 - 2.4e-194 646.6 0.3 2.8e-194 646.4 0.3 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EMT53696.1 - 0.00024 20.7 0.1 0.00097 18.7 0.0 2.0 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) Glyoxalase_4 PF13669.6 EMT53697.1 - 2.1e-23 82.7 0.0 1.2e-22 80.2 0.0 2.1 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily B12-binding PF02310.19 EMT53697.1 - 7.3e-23 80.9 0.3 2.7e-22 79.1 0.3 1.9 2 0 0 2 2 2 1 B12 binding domain Glyoxalase PF00903.25 EMT53697.1 - 9.2e-16 58.2 0.0 3.1e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EMT53697.1 - 7.9e-07 29.4 0.1 2e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain CbiX PF01903.17 EMT53697.1 - 0.036 14.4 0.0 0.17 12.2 0.0 2.3 1 1 0 1 1 1 0 CbiX Glyco_tran_WecB PF03808.13 EMT53697.1 - 0.13 12.2 0.0 0.36 10.7 0.0 1.7 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family MM_CoA_mutase PF01642.22 EMT53698.1 - 3e-236 784.9 0.1 3.4e-236 784.7 0.1 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase ROF PF07073.12 EMT53698.1 - 0.069 13.3 0.3 0.22 11.7 0.1 2.0 2 0 0 2 2 2 0 Modulator of Rho-dependent transcription termination (ROF) Met_asp_mut_E PF06368.11 EMT53698.1 - 0.084 11.3 0.2 0.15 10.5 0.2 1.4 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Cu_amine_oxidN1 PF07833.11 EMT53699.1 - 2.4e-23 82.4 14.9 4.6e-16 59.1 0.1 6.1 5 2 2 7 7 7 2 Copper amine oxidase N-terminal domain DUF2808 PF10989.8 EMT53699.1 - 3.8e-07 30.2 5.2 0.00072 19.6 0.0 4.3 3 2 1 4 4 4 2 Protein of unknown function (DUF2808) Peptidase_U32_C PF16325.5 EMT53699.1 - 0.15 12.3 0.1 7.8 6.8 0.1 2.5 2 0 0 2 2 2 0 Peptidase family U32 C-terminal domain Big_8 PF17961.1 EMT53699.1 - 0.93 9.7 23.3 0.43 10.8 0.9 5.0 3 2 2 5 5 5 0 Bacterial Ig domain DEC-1_N PF04625.13 EMT53699.1 - 2.4 7.1 15.1 1.8 7.5 5.7 2.2 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DUF916 PF06030.12 EMT53699.1 - 2.7 8.1 8.5 4.7 7.3 0.2 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF916) PLAT PF01477.23 EMT53699.1 - 4.6 7.8 7.8 9.5 6.8 0.9 3.4 2 1 0 3 3 3 0 PLAT/LH2 domain 2-oxoacid_dh PF00198.23 EMT53700.1 - 2.9e-82 275.6 0.6 4.2e-82 275.1 0.6 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EMT53700.1 - 5.3e-25 87.1 1.4 1.2e-24 85.9 1.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EMT53700.1 - 9.2e-13 48.3 0.0 3.2e-12 46.6 0.0 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EMT53700.1 - 1e-09 38.1 0.4 0.0014 18.4 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 EMT53700.1 - 0.00017 21.5 0.1 0.00063 19.7 0.1 2.0 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EMT53700.1 - 0.017 15.0 0.2 0.043 13.7 0.2 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 EMT53700.1 - 0.019 14.7 0.1 0.099 12.4 0.1 2.1 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Transket_pyr PF02779.24 EMT53701.1 - 1.6e-52 177.7 0.2 3.2e-52 176.8 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMT53701.1 - 3.9e-45 152.7 0.1 1.6e-44 150.7 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EMT53701.1 - 1.6e-05 25.1 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II E1_dh PF00676.20 EMT53702.1 - 4.1e-101 337.9 0.0 4.7e-101 337.7 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 EMT53702.1 - 0.00026 20.0 0.0 0.00039 19.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 EMT53702.1 - 0.00058 19.7 0.0 0.014 15.2 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EMT53702.1 - 0.091 12.0 0.0 0.2 10.8 0.0 1.5 1 1 1 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Pyr_redox_2 PF07992.14 EMT53703.1 - 2.7e-60 204.1 4.1 3.4e-60 203.8 4.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EMT53703.1 - 2.8e-36 124.1 1.5 5.7e-36 123.1 0.0 2.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EMT53703.1 - 4.1e-23 81.7 8.7 8.1e-21 74.4 0.7 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMT53703.1 - 5.2e-09 35.7 3.6 3.1e-07 29.8 0.1 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMT53703.1 - 3.9e-08 32.9 3.5 8.6e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMT53703.1 - 8.1e-07 28.5 3.1 0.0049 16.2 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EMT53703.1 - 1.6e-06 27.8 0.9 1.6e-06 27.8 0.9 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMT53703.1 - 3.5e-06 27.2 4.3 0.0037 17.5 1.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EMT53703.1 - 4.7e-06 26.6 0.1 4.7e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EMT53703.1 - 6e-06 25.6 8.2 9.5e-06 24.9 3.0 2.6 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EMT53703.1 - 8e-05 22.0 2.4 0.0069 15.7 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 EMT53703.1 - 0.00011 21.4 0.0 0.0014 17.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EMT53703.1 - 0.0003 19.6 8.5 0.00097 17.9 1.2 2.8 2 1 1 3 3 3 2 HI0933-like protein 2-Hacid_dh_C PF02826.19 EMT53703.1 - 0.00035 20.0 0.7 0.027 13.8 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 EMT53703.1 - 0.00067 18.6 4.4 0.037 12.9 0.3 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 EMT53703.1 - 0.0018 17.6 1.8 0.14 11.3 0.4 2.5 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EMT53703.1 - 0.0068 16.0 12.0 0.19 11.3 0.8 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EMT53703.1 - 0.012 16.0 2.6 0.13 12.7 0.3 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EMT53703.1 - 0.033 13.2 2.9 2 7.4 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein XdhC_C PF13478.6 EMT53703.1 - 0.039 14.5 0.1 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain AAA_26 PF13500.6 EMT53703.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain UDPG_MGDP_dh_N PF03721.14 EMT53703.1 - 0.41 10.2 3.0 0.6 9.7 0.0 2.5 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EMT53703.1 - 0.84 9.9 4.3 1.2 9.4 0.3 2.9 2 1 0 2 2 2 0 TrkA-N domain ELFV_dehydrog_N PF02812.18 EMT53704.1 - 2.1e-28 98.8 0.0 4.2e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 EMT53704.1 - 7.5e-19 68.4 1.3 2.6e-11 43.7 0.1 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 EMT53704.1 - 0.00018 20.9 0.0 0.00063 19.1 0.0 1.9 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 EMT53704.1 - 0.0002 21.0 0.1 0.001 18.7 0.1 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT53704.1 - 0.002 17.6 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase AdoHcyase_NAD PF00670.21 EMT53704.1 - 0.0026 17.8 0.3 0.0047 17.0 0.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 EMT53704.1 - 0.0054 17.0 0.4 0.015 15.5 0.2 1.8 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 EMT53704.1 - 0.014 15.8 0.2 0.051 14.0 0.1 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 EMT53704.1 - 0.032 14.4 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sigma54_activat PF00158.26 EMT53705.1 - 1.3e-71 239.7 0.2 2.6e-71 238.8 0.2 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain PAS PF00989.25 EMT53705.1 - 3.6e-30 104.2 1.0 2.9e-14 53.0 0.0 3.4 3 0 0 3 3 3 2 PAS fold Sigma54_activ_2 PF14532.6 EMT53705.1 - 2.1e-18 66.8 0.0 1e-17 64.6 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain PAS_4 PF08448.10 EMT53705.1 - 4.5e-18 65.5 1.1 1.1e-08 35.3 0.1 3.7 4 0 0 4 4 3 2 PAS fold PAS_9 PF13426.7 EMT53705.1 - 9.6e-18 64.4 0.1 6e-08 32.9 0.1 3.2 3 0 0 3 3 2 2 PAS domain HTH_8 PF02954.19 EMT53705.1 - 5.2e-11 42.2 3.9 8.1e-11 41.5 1.5 2.7 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family PAS_8 PF13188.7 EMT53705.1 - 1.3e-10 41.0 0.0 0.00099 19.1 0.0 3.3 2 0 0 2 2 2 2 PAS domain PAS_10 PF13596.6 EMT53705.1 - 4.2e-08 33.7 0.1 2.7e-05 24.7 0.1 3.4 3 0 0 3 3 3 1 PAS domain AAA PF00004.29 EMT53705.1 - 1e-07 32.4 0.0 2.8e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMT53705.1 - 6.5e-07 29.4 0.5 3.6e-06 27.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DapB_N PF01113.20 EMT53705.1 - 1.6e-05 25.1 0.0 5.4e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus AAA_2 PF07724.14 EMT53705.1 - 0.00094 19.3 0.1 0.0035 17.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) HTH_50 PF18024.1 EMT53705.1 - 0.0031 17.1 0.3 0.009 15.6 0.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain PAS_7 PF12860.7 EMT53705.1 - 0.0033 17.6 0.1 5.9 7.1 0.0 3.6 2 1 0 2 2 2 1 PAS fold HTH_30 PF13556.6 EMT53705.1 - 0.0045 16.8 1.1 0.0099 15.7 0.1 2.1 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain GFO_IDH_MocA PF01408.22 EMT53705.1 - 0.0062 17.4 0.0 0.028 15.3 0.0 2.2 2 0 0 2 2 1 1 Oxidoreductase family, NAD-binding Rossmann fold AAA_16 PF13191.6 EMT53705.1 - 0.016 15.6 0.3 0.073 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain sCache_3_3 PF17202.4 EMT53705.1 - 0.028 14.9 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Single cache domain 3 Semialdhyde_dh PF01118.24 EMT53705.1 - 0.032 14.7 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AAA_3 PF07726.11 EMT53705.1 - 0.032 14.1 0.0 0.089 12.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EMT53705.1 - 0.062 12.5 0.1 0.3 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) HTH_28 PF13518.6 EMT53705.1 - 0.068 13.3 1.6 0.097 12.8 0.2 2.1 2 0 0 2 2 1 0 Helix-turn-helix domain PglD_N PF17836.1 EMT53705.1 - 0.084 13.5 0.0 0.47 11.1 0.0 2.3 1 1 0 2 2 2 0 PglD N-terminal domain HTH_23 PF13384.6 EMT53705.1 - 0.16 11.8 0.3 0.65 9.9 0.3 2.1 1 0 0 1 1 1 0 Homeodomain-like domain Mg_chelatase PF01078.21 EMT53705.1 - 0.76 9.1 6.9 0.21 11.0 0.8 2.5 2 1 0 2 2 1 0 Magnesium chelatase, subunit ChlI DUF2627 PF11118.8 EMT53706.1 - 2.9e-30 104.6 3.7 3.3e-30 104.5 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2627) UPF0182 PF03699.13 EMT53706.1 - 0.24 9.5 0.3 0.25 9.4 0.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) RseC_MucC PF04246.12 EMT53706.1 - 0.55 10.2 1.7 0.8 9.7 1.7 1.3 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC COX8 PF02285.15 EMT53706.1 - 0.69 9.8 6.2 0.14 12.1 2.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII ABC2_membrane_2 PF12679.7 EMT53706.1 - 0.94 8.7 6.4 1.1 8.4 6.4 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4282 PF14110.6 EMT53706.1 - 1 10.1 7.4 1.3 9.8 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF2516 PF10724.9 EMT53707.1 - 4.4 7.7 10.0 4.5 7.6 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2516) Glycos_transf_2 PF00535.26 EMT53708.1 - 1.5e-23 83.4 0.0 2.2e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMT53708.1 - 6.8e-08 32.7 0.0 3e-05 24.0 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EMT53708.1 - 0.00087 19.8 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EMT53708.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MctB PF11382.8 EMT53709.1 - 1.1e-14 54.9 0.0 1.3e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Copper transport outer membrane protein, MctB Folate_carrier PF01770.18 EMT53709.1 - 0.094 11.4 0.1 0.13 11.0 0.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier Poly_export PF02563.16 EMT53709.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein ZapB PF06005.12 EMT53709.1 - 0.21 12.1 6.5 0.11 13.0 3.3 1.9 2 0 0 2 2 2 0 Cell division protein ZapB TPPK_C PF12555.8 EMT53710.1 - 3.8e-13 49.3 4.9 9.5e-13 48.0 4.9 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal TPK_catalytic PF04263.16 EMT53710.1 - 2.5e-07 30.8 0.2 1.1e-06 28.7 0.1 2.1 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain MAF_flag10 PF01973.18 EMT53710.1 - 0.00043 20.0 0.0 0.00089 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF115 Methyltransf_11 PF08241.12 EMT53712.1 - 4.1e-23 81.8 0.1 1.2e-22 80.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT53712.1 - 1.5e-19 70.5 0.1 3.5e-19 69.3 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT53712.1 - 1.6e-16 60.5 0.0 2.5e-16 59.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT53712.1 - 3.9e-13 49.6 0.0 5.6e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMT53712.1 - 2.4e-11 43.6 0.0 4.2e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EMT53712.1 - 3.3e-10 40.6 0.0 7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT53712.1 - 2.4e-06 27.1 0.0 8.5e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EMT53712.1 - 6.7e-06 25.7 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EMT53712.1 - 8e-05 21.7 0.0 0.00014 20.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 EMT53712.1 - 0.00038 20.1 0.0 0.00055 19.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 EMT53712.1 - 0.00051 19.4 0.0 0.0017 17.7 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase domain PCMT PF01135.19 EMT53712.1 - 0.0029 17.4 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EMT53712.1 - 0.0054 16.1 0.1 0.014 14.7 0.1 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PX PF00787.24 EMT53712.1 - 0.006 16.5 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 PX domain Methyltransf_18 PF12847.7 EMT53712.1 - 0.024 14.5 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 EMT53712.1 - 0.032 12.8 0.2 0.21 10.1 0.0 2.2 3 0 0 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NNMT_PNMT_TEMT PF01234.17 EMT53712.1 - 0.1 11.8 0.0 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Glyoxalase PF00903.25 EMT53713.1 - 1.2e-06 28.7 0.0 1.9e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EMT53713.1 - 0.0022 18.8 0.0 0.0026 18.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Methyltransf_11 PF08241.12 EMT53714.1 - 1e-23 83.8 0.0 1.8e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT53714.1 - 1.3e-21 77.1 0.0 2.2e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT53714.1 - 5.5e-15 55.5 0.0 7.6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT53714.1 - 8.2e-14 51.8 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT53714.1 - 5.4e-13 48.8 0.0 7.5e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMT53714.1 - 1.9e-10 41.4 0.0 3.8e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EMT53714.1 - 2.9e-05 22.8 0.0 2.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 EMT53714.1 - 0.0036 16.9 0.0 0.0075 15.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EMT53714.1 - 0.0051 16.3 0.0 0.19 11.1 0.0 2.4 1 1 0 1 1 1 1 Putative methyltransferase DREV PF05219.12 EMT53714.1 - 0.0098 15.0 0.0 0.04 13.0 0.0 1.6 1 1 1 2 2 2 1 DREV methyltransferase Methyltransf_8 PF05148.15 EMT53714.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_PK PF05891.12 EMT53714.1 - 0.028 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase RFC1 PF08519.12 EMT53714.1 - 0.046 13.9 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain RrnaAD PF00398.20 EMT53714.1 - 0.053 12.6 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.11 EMT53714.1 - 0.087 12.4 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Nodulation protein S (NodS) LysR_substrate PF03466.20 EMT53715.1 - 3.9e-40 137.5 0.3 6.7e-40 136.7 0.3 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT53715.1 - 4.7e-21 74.5 2.1 4.7e-21 74.5 2.1 2.4 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EMT53715.1 - 9.6e-06 25.3 0.5 3e-05 23.7 0.4 1.9 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_50 PF18024.1 EMT53715.1 - 0.058 13.0 0.1 0.2 11.3 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Phosphonate-bd PF12974.7 EMT53715.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Metallophos PF00149.28 EMT53716.1 - 6.2e-14 53.0 1.0 1e-13 52.3 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMT53716.1 - 7.3e-09 36.0 0.5 1.3e-08 35.2 0.5 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EMT53716.1 - 0.0047 16.3 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Pro_CA PF00484.19 EMT53717.1 - 3.3e-17 63.2 0.0 5.5e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Carbonic anhydrase Metallophos_2 PF12850.7 EMT53718.1 - 3.8e-29 102.0 0.0 4.8e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EMT53718.1 - 7.6e-15 56.0 0.3 2.5e-14 54.3 0.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 EMT53718.1 - 0.00033 20.1 0.2 0.23 10.8 0.0 2.7 3 0 0 3 3 3 2 Metallophosphoesterase, calcineurin superfamily Spo0A_C PF08769.11 EMT53720.1 - 1.1e-45 153.9 0.2 3e-45 152.6 0.2 1.7 1 0 0 1 1 1 1 Sporulation initiation factor Spo0A C terminal Response_reg PF00072.24 EMT53720.1 - 2.5e-27 95.2 0.5 4e-27 94.6 0.5 1.3 1 0 0 1 1 1 1 Response regulator receiver domain YtxC PF08812.11 EMT53720.1 - 0.017 14.7 0.2 0.061 12.9 0.1 1.8 2 0 0 2 2 2 0 YtxC-like family Peptidase_S55 PF05580.12 EMT53721.1 - 1.6e-89 299.4 1.1 2.4e-89 298.8 1.1 1.3 1 0 0 1 1 1 1 SpoIVB peptidase S55 PDZ_6 PF17820.1 EMT53721.1 - 9.6e-08 31.8 0.1 5.3e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EMT53721.1 - 2.6e-06 27.7 2.1 4e-05 23.9 0.5 3.1 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 EMT53721.1 - 0.0012 19.2 8.9 0.0097 16.2 0.6 4.1 5 0 0 5 5 5 1 PDZ domain Tricorn_PDZ PF14685.6 EMT53721.1 - 0.059 13.3 3.8 0.061 13.3 0.1 3.0 4 0 0 4 4 4 0 Tricorn protease PDZ domain AAA_23 PF13476.6 EMT53722.1 - 3.3e-17 63.7 9.8 8.8e-16 59.0 9.8 2.4 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EMT53722.1 - 7.4e-17 61.5 0.0 1.8e-16 60.2 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT53722.1 - 2.4e-07 30.8 0.0 8.6e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EMT53722.1 - 8.6e-07 29.1 0.2 0.0053 16.6 0.0 2.5 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT53722.1 - 1.3e-06 28.0 0.1 2.9e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1664 PF07889.12 EMT53722.1 - 0.001 19.1 4.5 0.28 11.2 0.4 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1664) DAO_C PF16901.5 EMT53722.1 - 0.037 13.9 0.4 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 C-terminal domain of alpha-glycerophosphate oxidase NTPase_P4 PF11602.8 EMT53722.1 - 0.039 13.2 0.2 0.093 11.9 0.1 1.5 2 0 0 2 2 2 0 ATPase P4 of dsRNA bacteriophage phi-12 AAA_22 PF13401.6 EMT53722.1 - 0.069 13.4 4.8 0.27 11.5 0.0 3.6 3 1 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EMT53722.1 - 0.12 12.2 0.8 0.76 9.7 0.2 2.4 2 0 0 2 2 2 0 RsgA GTPase NPV_P10 PF05531.12 EMT53722.1 - 0.19 12.2 10.0 0.24 11.9 0.2 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Cob_adeno_trans PF01923.18 EMT53722.1 - 0.85 9.7 7.3 6.9 6.8 0.8 3.1 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Laminin_II PF06009.12 EMT53722.1 - 0.93 9.5 6.4 0.67 10.0 0.8 2.8 1 1 1 3 3 3 0 Laminin Domain II Snapin_Pallidin PF14712.6 EMT53722.1 - 1.2 9.6 12.9 6.6 7.2 4.5 3.2 2 1 0 2 2 2 0 Snapin/Pallidin Seryl_tRNA_N PF02403.22 EMT53722.1 - 1.4 9.1 9.0 0.4 10.9 0.8 3.1 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ABC_tran PF00005.27 EMT53722.1 - 2.1 8.9 7.4 14 6.2 5.0 3.5 2 1 0 2 2 1 0 ABC transporter TMPIT PF07851.13 EMT53722.1 - 2.3 7.4 5.6 7.9 5.6 0.5 2.3 2 0 0 2 2 2 0 TMPIT-like protein RecG_N PF17190.4 EMT53722.1 - 4.8 8.0 8.9 0.35 11.6 0.8 3.1 3 2 0 3 3 3 0 RecG N-terminal helical domain BLOC1_2 PF10046.9 EMT53722.1 - 8.6 6.7 14.3 4 7.8 1.3 3.7 3 1 1 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Arg_repressor PF01316.21 EMT53723.1 - 6e-30 102.8 0.0 9.5e-30 102.2 0.0 1.3 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain Arg_repressor_C PF02863.18 EMT53723.1 - 8e-27 92.9 0.0 1.3e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Arginine repressor, C-terminal domain Flg_hook PF02120.16 EMT53723.1 - 0.13 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK NAD_kinase PF01513.21 EMT53724.1 - 1.1e-58 198.7 0.1 4.6e-58 196.7 0.1 1.7 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EMT53724.1 - 0.00075 19.1 0.5 0.0012 18.4 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain FtsJ PF01728.19 EMT53725.1 - 8e-18 65.2 0.0 9.9e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 EMT53725.1 - 3.6e-08 33.0 0.0 6.9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain Methyltransf_18 PF12847.7 EMT53725.1 - 0.093 12.7 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain DXP_synthase_N PF13292.6 EMT53726.1 - 3.7e-123 410.1 0.3 1.1e-122 408.5 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 EMT53726.1 - 2.8e-42 144.4 0.4 7.9e-42 142.9 0.1 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMT53726.1 - 8.9e-32 109.6 0.9 4.3e-31 107.4 0.0 2.4 3 0 0 3 3 3 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 EMT53726.1 - 8.5e-09 35.4 0.7 4e-07 30.0 0.7 2.5 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 EMT53726.1 - 8.4e-06 25.0 0.1 0.0027 16.7 0.0 2.4 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 EMT53726.1 - 0.0011 18.0 0.3 0.0023 16.9 0.3 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component PFOR_II PF17147.4 EMT53726.1 - 0.04 14.2 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II DUF5532 PF17673.1 EMT53726.1 - 0.18 11.9 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5532) Peptidase_M3 PF01432.20 EMT53727.1 - 9e-28 97.7 9.5 1.8e-20 73.6 2.8 2.1 2 0 0 2 2 2 2 Peptidase family M3 Phage_30_3 PF08010.11 EMT53727.1 - 0.14 11.9 0.4 0.41 10.4 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage protein GP30.3 Zeta_toxin PF06414.12 EMT53727.1 - 0.16 11.2 2.9 0.14 11.4 0.6 1.9 2 0 0 2 2 2 0 Zeta toxin polyprenyl_synt PF00348.17 EMT53728.1 - 7.8e-60 202.1 0.1 9.6e-60 201.8 0.1 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Exonuc_VII_S PF02609.16 EMT53729.1 - 1.3e-21 76.4 2.7 1.7e-21 76.0 2.7 1.2 1 0 0 1 1 1 1 Exonuclease VII small subunit DUF1657 PF07870.11 EMT53729.1 - 0.0044 16.9 1.0 0.0089 15.9 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1657) DUF2802 PF10975.8 EMT53729.1 - 0.019 15.0 1.8 0.25 11.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) HTH_7 PF02796.15 EMT53729.1 - 0.043 13.9 0.4 2.8 8.1 0.4 2.4 1 1 0 1 1 1 0 Helix-turn-helix domain of resolvase Trimer_CC PF08954.11 EMT53729.1 - 0.044 13.3 1.9 0.2 11.2 1.1 2.5 2 1 0 2 2 2 0 Trimerisation motif DUF2089 PF09862.9 EMT53729.1 - 0.055 13.5 0.8 0.1 12.7 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) RPW8 PF05659.11 EMT53729.1 - 0.056 13.1 0.2 0.069 12.8 0.2 1.1 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CM_2 PF01817.21 EMT53729.1 - 0.06 13.7 2.2 3.4 8.1 0.3 2.1 2 0 0 2 2 2 0 Chorismate mutase type II MIT PF04212.18 EMT53729.1 - 0.071 13.2 2.1 0.23 11.6 0.2 2.3 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EMT53729.1 - 0.11 12.4 2.4 1.6 8.7 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Toprim_C_rpt PF13368.6 EMT53729.1 - 0.12 12.3 0.6 2.9 7.9 0.2 2.2 1 1 1 2 2 2 0 Topoisomerase C-terminal repeat Exonuc_VII_L PF02601.15 EMT53730.1 - 3.5e-104 348.6 0.7 4.2e-104 348.4 0.7 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 EMT53730.1 - 4.2e-30 103.8 0.1 1.4e-29 102.2 0.1 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 EMT53730.1 - 1.9e-07 31.0 0.0 4.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Glyco_tran_WecB PF03808.13 EMT53730.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family DUF759 PF05537.11 EMT53730.1 - 0.11 11.4 0.9 0.16 10.8 0.9 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) THF_DHG_CYH_C PF02882.19 EMT53731.1 - 7.5e-72 239.9 3.3 7.5e-72 239.9 3.3 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EMT53731.1 - 5.9e-41 139.4 0.2 9.6e-41 138.7 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Peptidase_M22 PF00814.25 EMT53732.1 - 1.3e-32 113.6 0.0 1.7e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family NusB PF01029.18 EMT53733.1 - 8e-36 123.2 0.6 9.4e-36 123.0 0.6 1.1 1 0 0 1 1 1 1 NusB family DnaB_2 PF07261.11 EMT53733.1 - 0.0046 16.7 0.1 0.057 13.2 0.0 2.1 2 0 0 2 2 2 1 Replication initiation and membrane attachment ANAPC5 PF12862.7 EMT53733.1 - 0.0083 16.2 0.0 0.011 15.8 0.0 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 5 Toprim_C_rpt PF13368.6 EMT53733.1 - 0.13 12.3 0.4 5.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Topoisomerase C-terminal repeat DUF2273 PF10031.9 EMT53734.1 - 1.8e-17 63.1 7.8 2.1e-17 62.8 7.8 1.1 1 0 0 1 1 1 1 Small integral membrane protein (DUF2273) Asp23 PF03780.13 EMT53735.1 - 2.2e-08 34.5 5.0 0.00014 22.2 2.0 2.2 1 1 1 2 2 2 2 Asp23 family, cell envelope-related function CorC_HlyC PF03471.17 EMT53735.1 - 0.011 15.8 0.2 0.026 14.6 0.0 1.7 2 0 0 2 2 2 0 Transporter associated domain ZT_dimer PF16916.5 EMT53735.1 - 0.018 15.2 0.3 0.032 14.4 0.3 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter PTR2 PF00854.21 EMT53735.1 - 0.037 12.9 0.0 0.061 12.1 0.0 1.4 1 1 0 1 1 1 0 POT family DUF2207 PF09972.9 EMT53735.1 - 0.04 12.7 1.1 0.11 11.3 0.4 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MnmE_helical PF12631.7 EMT53735.1 - 0.14 12.3 0.2 0.19 11.8 0.2 1.1 1 0 0 1 1 1 0 MnmE helical domain Asp23 PF03780.13 EMT53736.1 - 6.9e-38 129.4 8.3 8e-38 129.2 8.3 1.0 1 0 0 1 1 1 1 Asp23 family, cell envelope-related function FeS_assembly_P PF01883.19 EMT53736.1 - 0.067 13.4 0.5 0.067 13.4 0.5 1.7 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein CPSase_L_D2 PF02786.17 EMT53737.1 - 1.4e-86 289.3 0.1 2.3e-86 288.7 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EMT53737.1 - 2.7e-48 163.1 0.7 5.8e-48 162.0 0.3 1.8 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EMT53737.1 - 8.3e-45 151.3 0.0 2e-44 150.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EMT53737.1 - 2.2e-12 47.0 0.0 4.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EMT53737.1 - 3.3e-10 39.8 0.1 6.3e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EMT53737.1 - 6.4e-06 26.3 0.0 9.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EMT53737.1 - 8.8e-05 22.4 0.1 0.00019 21.2 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 EMT53737.1 - 0.0029 17.1 0.3 0.0071 15.8 0.3 1.6 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EMT53737.1 - 0.0051 16.4 0.0 0.072 12.7 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 EMT53737.1 - 0.0098 15.5 0.0 0.033 13.8 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EMT53737.1 - 0.01 15.1 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Oxidored_nitro PF00148.19 EMT53737.1 - 0.013 14.2 0.0 0.033 12.9 0.0 1.6 1 1 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ATPgrasp_Ter PF15632.6 EMT53737.1 - 0.027 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_YheCD PF14398.6 EMT53737.1 - 0.22 10.7 0.0 1.7 7.9 0.0 2.0 2 0 0 2 2 2 0 YheC/D like ATP-grasp Biotin_lipoyl PF00364.22 EMT53738.1 - 3.9e-22 77.9 1.7 3.5e-21 74.8 0.3 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EMT53738.1 - 2e-06 27.5 0.5 5.6e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.19 EMT53738.1 - 0.017 15.0 0.3 0.017 15.0 0.3 2.0 2 1 0 2 2 2 0 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 EMT53738.1 - 0.026 14.3 0.3 3.1 7.5 0.1 3.0 2 1 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF2742 PF10888.8 EMT53738.1 - 0.033 14.4 0.4 0.087 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) HlyD_3 PF13437.6 EMT53738.1 - 0.043 14.5 1.7 0.083 13.6 0.1 2.3 3 1 0 3 3 3 0 HlyD family secretion protein RnfC_N PF13375.6 EMT53738.1 - 0.21 11.6 2.6 0.64 10.0 0.2 2.5 1 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain SpoIIIAH PF12685.7 EMT53739.1 - 2.9e-42 144.9 11.7 3.3e-42 144.7 11.7 1.0 1 0 0 1 1 1 1 SpoIIIAH-like protein LAMTOR PF15454.6 EMT53739.1 - 9 7.0 10.3 7 7.3 0.1 3.4 4 0 0 4 4 4 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator GUN4_N PF16416.5 EMT53740.1 - 0.12 12.4 0.0 0.42 10.6 0.0 1.9 1 0 0 1 1 1 0 ARM-like repeat domain, GUN4-N terminal Spore_III_AF PF09581.10 EMT53741.1 - 7e-41 140.3 3.9 8.1e-41 140.1 3.9 1.0 1 0 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) OppC_N PF12911.7 EMT53741.1 - 0.014 15.4 0.8 4.9 7.2 0.1 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Tautomerase_2 PF14552.6 EMT53741.1 - 0.04 14.0 0.2 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Tautomerase enzyme DUF4179 PF13786.6 EMT53741.1 - 0.1 13.1 3.8 0.39 11.2 3.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Spore_III_AE PF09546.10 EMT53742.1 - 1.1e-102 343.6 43.2 1.4e-102 343.2 43.2 1.1 1 0 0 1 1 1 1 Stage III sporulation protein AE (spore_III_AE) PhoLip_ATPase_N PF16209.5 EMT53742.1 - 1.1 9.0 5.0 12 5.6 0.1 3.7 3 0 0 3 3 3 0 Phospholipid-translocating ATPase N-terminal SpoIIIAC PF06686.11 EMT53743.1 - 1.9e-31 108.0 24.6 2.5e-19 69.2 8.7 2.0 2 0 0 2 2 2 2 Stage III sporulation protein AC/AD protein family LysE PF01810.18 EMT53743.1 - 0.02 14.4 3.0 0.086 12.3 0.1 2.2 1 1 1 2 2 2 0 LysE type translocator SpoIIIAC PF06686.11 EMT53744.1 - 1.4e-15 57.2 0.2 1.5e-15 57.1 0.2 1.0 1 0 0 1 1 1 1 Stage III sporulation protein AC/AD protein family TrbL PF04610.14 EMT53744.1 - 0.0048 16.7 0.8 0.0052 16.6 0.8 1.0 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Spore_III_AB PF09548.10 EMT53745.1 - 1.4e-49 168.5 0.7 1.5e-49 168.4 0.7 1.0 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) DGF-1_C PF11040.8 EMT53745.1 - 0.23 11.5 1.1 0.42 10.6 1.1 1.5 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2526 PF10735.9 EMT53745.1 - 0.49 10.6 9.7 0.18 12.0 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2526) TniB PF05621.11 EMT53746.1 - 0.0029 17.1 0.0 0.59 9.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial TniB protein AAA PF00004.29 EMT53746.1 - 0.011 16.2 0.0 0.033 14.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EMT53746.1 - 0.034 14.1 0.0 9.9 6.0 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 EMT53746.1 - 0.043 13.4 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EMT53746.1 - 0.16 11.7 0.0 1.2 8.9 0.0 2.1 1 1 1 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain MitMem_reg PF13012.6 EMT53747.1 - 0.029 14.8 0.0 0.034 14.6 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Zn_Tnp_IS1 PF03811.13 EMT53747.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 InsA N-terminal domain DUF2619 PF10942.8 EMT53748.1 - 4e-29 100.5 6.5 5.1e-29 100.2 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2619) Chloroplast_duf PF14476.6 EMT53748.1 - 0.015 14.3 0.5 0.018 14.0 0.4 1.3 1 1 0 1 1 1 0 Petal formation-expressed ComA PF02679.15 EMT53749.1 - 8.6e-80 267.7 0.0 9.9e-80 267.5 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) 2-ph_phosp PF04029.14 EMT53750.1 - 4.7e-66 222.2 0.0 5.3e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 2-phosphosulpholactate phosphatase DUF441 PF04284.13 EMT53751.1 - 5.4e-47 159.3 17.0 6.1e-47 159.1 17.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF441) CPP1-like PF11833.8 EMT53751.1 - 0.12 12.0 2.2 0.086 12.5 0.9 1.4 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like EFP_N PF08207.12 EMT53752.1 - 5.8e-28 96.7 0.2 1.5e-27 95.4 0.2 1.7 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 EMT53752.1 - 1.6e-27 95.0 2.5 2.6e-27 94.3 0.8 2.2 3 0 0 3 3 3 1 Elongation factor P, C-terminal EFP PF01132.20 EMT53752.1 - 2.2e-20 72.4 3.3 3.6e-20 71.7 3.3 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain gag-asp_proteas PF13975.6 EMT53752.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease TAF8_C PF10406.9 EMT53752.1 - 0.2 12.2 0.1 0.34 11.5 0.1 1.4 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term Peptidase_M24 PF00557.24 EMT53753.1 - 7.9e-64 215.2 0.6 1.8e-63 214.0 0.4 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EMT53753.1 - 3.7e-27 95.6 0.0 6.1e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DHquinase_II PF01220.19 EMT53754.1 - 1.2e-60 203.1 0.1 1.4e-60 203.0 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II YqhR PF11085.8 EMT53755.1 - 2.5e-12 47.1 9.5 4.9e-12 46.1 9.5 1.5 1 1 0 1 1 1 1 Conserved membrane protein YqhR Phage_holin_3_6 PF07332.11 EMT53755.1 - 2.6 8.1 13.3 0.49 10.4 9.0 2.0 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1385 PF07136.11 EMT53756.1 - 7.4e-83 277.3 0.3 8.9e-83 277.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1385) Oxidored_q4 PF00507.19 EMT53756.1 - 0.0015 18.7 0.9 0.0015 18.7 0.9 2.0 1 1 1 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 CAAD PF14159.6 EMT53756.1 - 0.29 11.0 3.6 2.6 7.9 0.0 3.4 4 1 0 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF2062 PF09835.9 EMT53756.1 - 0.81 9.5 7.7 2.3 8.1 7.8 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Lectin_N PF03954.14 EMT53757.1 - 0.086 12.6 0.7 0.17 11.6 0.7 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain CDC73_C PF05179.14 EMT53757.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal Pox_Ag35 PF03286.14 EMT53757.1 - 0.27 11.0 1.8 0.34 10.7 1.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Patatin PF01734.22 EMT53758.1 - 6.4e-26 91.8 0.3 2.3e-25 90.0 0.3 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Fe_dep_repress PF01325.19 EMT53759.1 - 3.9e-25 87.8 1.2 6e-25 87.2 1.2 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.15 EMT53759.1 - 2.2e-18 66.1 0.6 1.2e-17 63.8 0.2 2.1 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain MarR_2 PF12802.7 EMT53759.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EMT53759.1 - 1.6e-05 24.7 0.0 4.2e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 EMT53759.1 - 0.00033 20.1 0.0 0.00057 19.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 EMT53759.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 EMT53759.1 - 0.0023 17.8 0.2 0.013 15.4 0.3 2.1 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 EMT53759.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 EMT53759.1 - 0.016 15.1 0.1 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 HTH domain Rrf2 PF02082.20 EMT53759.1 - 0.029 14.7 0.1 0.068 13.5 0.1 1.7 1 1 0 1 1 1 0 Transcriptional regulator HTH_5 PF01022.20 EMT53759.1 - 0.038 13.9 0.3 0.21 11.5 0.0 2.3 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family HTH_38 PF13936.6 EMT53759.1 - 0.053 13.3 0.1 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain PTS_2-RNA PF01885.16 EMT53759.1 - 0.078 13.0 0.1 0.088 12.9 0.1 1.2 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family TetR_N PF00440.23 EMT53759.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_17 PF12728.7 EMT53759.1 - 0.091 13.0 0.0 1.3 9.3 0.0 2.6 1 1 1 2 2 2 0 Helix-turn-helix domain AbiEi_4 PF13338.6 EMT53759.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin HTH_28 PF13518.6 EMT53759.1 - 0.12 12.5 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain FMN_red PF03358.15 EMT53760.1 - 2.1e-36 125.0 0.0 2.5e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EMT53760.1 - 5.9e-09 35.9 0.0 8.9e-09 35.3 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold PAS_4 PF08448.10 EMT53762.1 - 2.3e-28 98.6 0.0 2.5e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 EMT53762.1 - 1.6e-27 95.6 0.5 2.5e-16 59.8 0.0 3.2 4 0 0 4 4 4 2 PAS fold PAS PF00989.25 EMT53762.1 - 6.1e-26 90.6 0.0 8.7e-12 45.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EMT53762.1 - 2.4e-22 79.1 0.0 1.4e-12 47.8 0.0 2.6 2 0 0 2 2 2 2 PAS domain HATPase_c PF02518.26 EMT53762.1 - 1.2e-21 77.3 0.0 3.2e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT53762.1 - 1.1e-15 57.4 1.2 4.8e-15 55.3 0.1 2.5 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 EMT53762.1 - 1.2e-10 41.1 0.0 9.2e-05 22.4 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS_11 PF14598.6 EMT53762.1 - 4.8e-08 33.1 0.0 1.3e-06 28.5 0.0 2.7 2 1 0 2 2 2 1 PAS domain PAS_10 PF13596.6 EMT53762.1 - 1.2e-05 25.8 0.0 0.044 14.4 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_7 PF12860.7 EMT53762.1 - 0.0075 16.4 0.3 0.7 10.1 0.0 3.7 3 2 0 3 3 3 1 PAS fold HATPase_c_2 PF13581.6 EMT53762.1 - 0.02 14.9 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EMT53762.1 - 0.021 14.7 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Casc1 PF12366.8 EMT53762.1 - 0.097 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 HPTransfase PF10090.9 EMT53762.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain sCache_3_3 PF17202.4 EMT53762.1 - 0.13 12.7 0.0 27 5.3 0.0 2.6 2 0 0 2 2 2 0 Single cache domain 3 dCache_1 PF02743.18 EMT53762.1 - 0.14 12.0 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Cache domain PA PF02225.22 EMT53763.1 - 9.3e-12 44.8 1.5 5.8e-11 42.3 0.6 2.3 2 0 0 2 2 2 1 PA domain Peptidase_M28 PF04389.17 EMT53763.1 - 7.9e-11 42.0 0.2 1.1e-10 41.5 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M28 Aminotran_4 PF01063.19 EMT53764.1 - 2.8e-48 164.7 0.0 3.3e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Citrate_ly_lig PF08218.11 EMT53764.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain BPL_LplA_LipB PF03099.19 EMT53765.1 - 8.4e-27 93.6 0.0 1.2e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GntR PF00392.21 EMT53765.1 - 0.11 12.1 0.1 2.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family SUI1 PF01253.22 EMT53765.1 - 0.13 12.8 0.2 0.33 11.5 0.0 1.7 2 0 0 2 2 2 0 Translation initiation factor SUI1 GDC-P PF02347.16 EMT53766.1 - 2.7e-16 59.4 0.0 1.3e-15 57.2 0.0 1.8 1 1 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EMT53766.1 - 7.2e-09 35.1 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMT53766.1 - 4.2e-05 23.0 0.0 6.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EMT53766.1 - 0.15 10.5 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GDC-P PF02347.16 EMT53767.1 - 1.5e-153 511.6 0.1 1.8e-153 511.5 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EMT53767.1 - 1e-05 24.7 2.2 4.7e-05 22.5 2.2 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMT53767.1 - 0.00087 18.6 0.1 0.049 12.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMT53767.1 - 0.0049 16.2 0.3 0.0078 15.6 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GCV_T PF01571.21 EMT53768.1 - 9e-94 313.6 0.0 1.1e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EMT53768.1 - 7e-25 86.8 0.1 1.2e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 EMT53768.1 - 1.2e-06 28.7 0.0 0.00011 22.4 0.0 2.2 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family SNF2_N PF00176.23 EMT53769.1 - 3.9e-36 124.5 0.1 7.3e-36 123.6 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMT53769.1 - 1.6e-21 76.7 0.7 5.5e-21 75.0 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMT53769.1 - 2.3e-14 53.7 0.7 1.1e-13 51.6 0.1 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMT53769.1 - 1.7e-06 27.9 0.4 1.8e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.6 EMT53769.1 - 0.0032 16.4 0.5 0.051 12.5 0.1 2.4 2 1 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 DUF2075 PF09848.9 EMT53769.1 - 0.011 15.0 0.0 0.029 13.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ribosomal_L31e PF01198.19 EMT53769.1 - 0.031 14.5 2.1 0.031 14.5 0.2 2.0 2 0 0 2 2 2 0 Ribosomal protein L31e IMPDH PF00478.25 EMT53769.1 - 0.032 13.2 0.1 2.8 6.8 0.0 2.3 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain PBECR3 PF18812.1 EMT53769.1 - 0.049 13.6 3.5 3.1 7.8 0.3 2.5 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 AAA_30 PF13604.6 EMT53769.1 - 0.072 12.8 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain BLI1 PF17324.2 EMT53769.1 - 0.077 13.7 4.6 0.43 11.3 0.3 3.5 4 0 0 4 4 4 0 BLOC-1 interactor 1 MSA-2c PF12238.8 EMT53769.1 - 0.29 11.1 2.5 2.2 8.3 0.1 2.8 2 1 1 3 3 3 0 Merozoite surface antigen 2c YqhG PF11079.8 EMT53770.1 - 4.8e-71 238.7 0.2 6e-64 215.5 0.2 2.1 2 0 0 2 2 2 2 Bacterial protein YqhG of unknown function HAUS6_N PF14661.6 EMT53770.1 - 0.042 13.4 0.2 0.097 12.2 0.2 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Gal-bind_lectin PF00337.22 EMT53770.1 - 0.15 11.6 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Galactoside-binding lectin DUF4407 PF14362.6 EMT53770.1 - 3.7 6.8 7.1 4.7 6.5 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0180 PF03698.13 EMT53772.1 - 1e-24 86.5 0.4 1.1e-24 86.3 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0180) LytR_C PF13399.6 EMT53772.1 - 0.0033 18.4 0.1 0.0046 17.9 0.1 1.4 1 1 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator YqzE PF14038.6 EMT53773.1 - 1.6e-19 69.6 0.7 1.9e-19 69.4 0.7 1.1 1 0 0 1 1 1 1 YqzE-like protein SKI PF01202.22 EMT53774.1 - 2.2e-39 135.1 0.1 2.5e-39 135.0 0.1 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 EMT53774.1 - 2.8e-09 37.6 0.0 4.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMT53774.1 - 0.0022 18.1 0.1 0.0053 16.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EMT53774.1 - 0.0025 18.2 0.8 0.25 11.8 0.8 2.3 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 EMT53774.1 - 0.014 15.6 0.7 0.66 10.1 0.1 2.5 1 1 1 3 3 3 0 Cytidylate kinase-like family AAA PF00004.29 EMT53774.1 - 0.019 15.4 0.1 0.028 14.8 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMT53774.1 - 0.029 14.6 0.2 0.052 13.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMT53774.1 - 0.051 14.0 1.0 0.27 11.6 1.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EMT53774.1 - 0.11 12.2 0.1 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cu_amine_oxidN1 PF07833.11 EMT53775.1 - 8.1e-17 61.5 0.0 1.5e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase N-terminal domain Peptidase_M1 PF01433.20 EMT53775.1 - 1.1e-09 38.1 0.4 1.9e-09 37.5 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DUF756 PF05506.12 EMT53775.1 - 0.028 15.3 0.0 4.7 8.2 0.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF756) PBP_like PF12727.7 EMT53776.1 - 1.6e-55 187.3 0.0 2.1e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 PBP superfamily domain HTH_17 PF12728.7 EMT53776.1 - 1.3e-16 60.5 0.2 3.2e-16 59.2 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain SBP_bac_11 PF13531.6 EMT53776.1 - 0.0023 17.7 0.0 0.0057 16.4 0.0 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein HTH_23 PF13384.6 EMT53776.1 - 0.065 13.1 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain UPF0122 PF04297.14 EMT53776.1 - 0.12 12.6 0.1 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_22 PF13309.6 EMT53776.1 - 0.15 12.1 1.2 0.35 11.0 0.1 2.1 2 0 0 2 2 2 0 HTH domain SBP_bac_11 PF13531.6 EMT53777.1 - 4.3e-55 186.9 0.4 5.3e-55 186.7 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT53777.1 - 1e-19 71.7 0.8 1.3e-18 68.0 0.8 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like_2 PF12849.7 EMT53777.1 - 7.9e-06 25.7 2.2 0.00035 20.4 0.2 2.3 2 1 0 2 2 2 2 PBP superfamily domain Phosphonate-bd PF12974.7 EMT53777.1 - 1.7e-05 24.5 0.3 2.4e-05 24.1 0.3 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_6 PF13343.6 EMT53777.1 - 0.0052 16.2 0.4 0.062 12.7 0.4 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 EMT53778.1 - 5.9e-22 78.3 15.2 8.4e-22 77.8 15.2 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component 7tm_7 PF08395.12 EMT53778.1 - 2.4 7.3 7.4 2 7.5 0.9 2.6 2 1 1 3 3 3 0 7tm Chemosensory receptor ABC_tran PF00005.27 EMT53779.1 - 8.8e-34 117.0 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT53779.1 - 2e-10 41.0 0.5 0.0005 20.0 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT53779.1 - 4.8e-07 29.5 0.0 1.6e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMT53779.1 - 1.8e-05 25.4 0.1 2.9e-05 24.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EMT53779.1 - 9.7e-05 22.8 0.0 0.0012 19.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EMT53779.1 - 0.00019 21.4 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EMT53779.1 - 0.00025 21.4 0.1 0.00059 20.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT53779.1 - 0.00038 20.1 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT53779.1 - 0.0004 20.8 0.3 0.0015 18.9 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 EMT53779.1 - 0.0023 17.4 0.0 0.47 9.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein SbcCD_C PF13558.6 EMT53779.1 - 0.0048 17.1 0.2 0.091 13.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.6 EMT53779.1 - 0.0071 16.7 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMT53779.1 - 0.0093 15.7 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EMT53779.1 - 0.016 15.1 0.0 0.017 15.0 0.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 EMT53779.1 - 0.024 13.7 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 EMT53779.1 - 0.026 14.4 0.0 0.07 13.0 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 EMT53779.1 - 0.03 13.9 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMT53779.1 - 0.036 14.3 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMT53779.1 - 0.06 13.9 0.2 1.1 9.8 0.2 2.2 1 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EMT53779.1 - 0.078 12.7 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EMT53779.1 - 0.083 13.1 0.2 0.22 11.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMT53779.1 - 0.092 12.7 0.0 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EMT53779.1 - 0.12 11.6 0.2 0.73 9.0 0.0 2.1 2 1 1 3 3 3 0 NB-ARC domain cobW PF02492.19 EMT53779.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 EMT53779.1 - 0.17 11.3 0.0 0.41 10.0 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EMT53779.1 - 0.19 11.4 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 EMT53779.1 - 0.26 9.9 0.0 0.38 9.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase LamB_YcsF PF03746.16 EMT53780.1 - 5.1e-88 294.8 0.0 6.4e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family DUF2129 PF09902.9 EMT53781.1 - 5.3e-26 90.5 0.2 7.2e-26 90.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2129) Com_YlbF PF06133.11 EMT53783.1 - 1.5e-22 80.2 5.9 1.9e-22 79.8 5.9 1.1 1 0 0 1 1 1 1 Control of competence regulator ComK, YlbF/YmcA Atg14 PF10186.9 EMT53783.1 - 0.0035 16.5 1.2 0.0041 16.3 1.2 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 EMT53783.1 - 0.043 14.2 2.8 1.3 9.5 0.4 2.6 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DUF4363 PF14276.6 EMT53783.1 - 0.048 13.8 2.9 0.16 12.1 2.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) Ribosomal_L30_N PF08079.12 EMT53783.1 - 0.85 9.9 4.7 0.75 10.1 2.9 1.8 1 1 1 2 2 2 0 Ribosomal L30 N-terminal domain Helicase_C_3 PF13625.6 EMT53784.1 - 0.00016 21.8 0.0 0.00038 20.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PrcB_C PF14343.6 EMT53785.1 - 5.9e-16 58.4 1.3 1.1e-15 57.5 1.3 1.5 1 0 0 1 1 1 1 PrcB C-terminal DUF4399 PF14347.6 EMT53786.1 - 0.0025 18.1 0.3 3.3 8.2 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4399) DUF2846 PF11008.8 EMT53786.1 - 0.0027 17.7 0.1 0.0081 16.2 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2846) CARDB PF07705.11 EMT53786.1 - 0.014 15.7 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 CARDB SNase PF00565.17 EMT53787.1 - 1.8e-30 105.6 0.2 4.9e-30 104.2 0.0 1.8 2 0 0 2 2 2 1 Staphylococcal nuclease homologue Presenilin PF01080.17 EMT53787.1 - 4.3 6.0 4.6 6.1 5.5 4.6 1.3 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 EMT53787.1 - 7.5 5.2 6.7 9.3 4.9 6.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MerR_1 PF13411.6 EMT53788.1 - 4.8e-20 71.4 2.6 5.4e-20 71.3 0.3 2.4 3 0 0 3 3 2 1 MerR HTH family regulatory protein Methyltransf_11 PF08241.12 EMT53788.1 - 6.2e-18 65.2 0.0 1.3e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMT53788.1 - 3.4e-17 62.9 0.0 9.9e-17 61.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT53788.1 - 5.3e-15 55.6 0.0 3.2e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT53788.1 - 7.6e-12 45.8 0.0 1.6e-10 41.6 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain MerR PF00376.23 EMT53788.1 - 9.4e-12 44.5 0.0 1.9e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 MerR family regulatory protein Methyltransf_31 PF13847.6 EMT53788.1 - 1.3e-10 41.3 0.0 2.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT53788.1 - 3.3e-08 33.2 0.0 5.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EMT53788.1 - 2.6e-05 23.6 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MerR-DNA-bind PF09278.11 EMT53788.1 - 0.0001 22.8 0.5 0.0011 19.5 0.1 2.9 2 0 0 2 2 2 1 MerR, DNA binding Methyltransf_8 PF05148.15 EMT53788.1 - 0.00056 19.8 0.1 0.69 9.7 0.0 2.5 2 1 1 3 3 3 2 Hypothetical methyltransferase Methyltransf_PK PF05891.12 EMT53788.1 - 0.0012 18.5 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MerR_2 PF13591.6 EMT53788.1 - 0.002 18.0 0.3 0.0091 15.8 0.6 2.0 2 0 0 2 2 2 1 MerR HTH family regulatory protein NNMT_PNMT_TEMT PF01234.17 EMT53788.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family HTH_19 PF12844.7 EMT53788.1 - 0.21 11.6 1.4 31 4.7 0.1 3.4 3 1 0 3 3 3 0 Helix-turn-helix domain DUF4954 PF16314.5 EMT53788.1 - 0.24 9.5 1.2 0.48 8.5 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) CBS PF00571.28 EMT53789.1 - 6.6e-25 87.3 7.7 1.3e-12 47.9 0.3 2.1 2 0 0 2 2 2 2 CBS domain GAF_2 PF13185.6 EMT53789.1 - 0.043 14.1 0.1 0.34 11.2 0.1 2.0 1 1 1 2 2 2 0 GAF domain Rubredoxin_C PF18267.1 EMT53789.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Rubredoxin NAD+ reductase C-terminal domain H_kinase_N PF12282.8 EMT53789.1 - 0.26 11.3 1.8 1.9 8.4 0.3 2.1 1 1 1 2 2 2 0 Signal transduction histidine kinase YugN PF08868.10 EMT53790.1 - 4.1e-19 68.8 0.3 8e-19 67.8 0.2 1.4 1 1 1 2 2 2 1 YugN-like family FTSW_RODA_SPOVE PF01098.19 EMT53791.1 - 9.8e-105 350.5 29.3 1.3e-104 350.0 29.3 1.1 1 0 0 1 1 1 1 Cell cycle protein Asp23 PF03780.13 EMT53792.1 - 1.9e-26 92.6 6.4 2.1e-26 92.5 6.4 1.0 1 0 0 1 1 1 1 Asp23 family, cell envelope-related function FeS_assembly_P PF01883.19 EMT53792.1 - 0.012 15.7 0.8 0.028 14.6 0.7 1.9 1 1 0 1 1 1 0 Iron-sulfur cluster assembly protein TPP_enzyme_N PF02776.18 EMT53793.1 - 4.7e-47 159.8 0.6 1.2e-46 158.4 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMT53793.1 - 1.9e-34 118.7 0.3 5.1e-34 117.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMT53793.1 - 1.9e-23 82.7 0.2 1e-21 77.1 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EMT53793.1 - 0.00046 20.0 0.0 0.0008 19.2 0.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DXP_synthase_N PF13292.6 EMT53793.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 EMT53793.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain Hydrolase_2 PF07486.12 EMT53794.1 - 1.6e-28 99.6 0.0 2.7e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Cell Wall Hydrolase PG_binding_1 PF01471.18 EMT53794.1 - 2.6e-15 56.4 0.0 6.2e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_2 PF08823.11 EMT53794.1 - 0.0014 18.9 0.1 0.0055 17.0 0.1 1.9 2 0 0 2 2 2 1 Putative peptidoglycan binding domain WW PF00397.26 EMT53794.1 - 0.0051 16.9 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 WW domain Baculo_IE-1 PF05290.11 EMT53795.1 - 0.049 13.6 0.4 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) TF_Zn_Ribbon PF08271.12 EMT53795.1 - 0.075 12.6 0.8 7.1 6.2 0.2 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 EMT53795.1 - 0.55 10.6 2.7 1.9 8.9 2.7 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar Na_Ca_ex PF01699.24 EMT53796.1 - 5e-35 120.7 41.6 1.6e-18 67.1 13.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SNF PF00209.18 EMT53797.1 - 1.8e-54 185.4 38.1 1.1e-30 106.9 21.1 2.1 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family DUF5360 PF17314.2 EMT53797.1 - 0.095 12.8 0.1 0.095 12.8 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5360) DUF1507 PF07408.11 EMT53798.1 - 5.3e-39 132.0 0.5 5.9e-39 131.8 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1507) Glutaminase PF04960.15 EMT53799.1 - 2.1e-118 394.7 0.0 2.4e-118 394.5 0.0 1.0 1 0 0 1 1 1 1 Glutaminase Sda PF08970.10 EMT53801.1 - 2.4e-17 62.4 0.1 2.4e-17 62.4 0.1 1.0 1 0 0 1 1 1 1 Sporulation inhibitor A Aminotran_3 PF00202.21 EMT53802.1 - 1.2e-130 435.8 0.0 1.4e-130 435.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMT53802.1 - 0.00073 18.8 0.0 0.0011 18.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMT53802.1 - 0.0022 17.4 0.0 0.007 15.7 0.0 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EMT53802.1 - 0.0035 16.4 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Sigma54_activat PF00158.26 EMT53803.1 - 2.1e-62 209.7 0.0 1.9e-61 206.6 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT53803.1 - 9.5e-19 67.9 0.0 2.5e-18 66.5 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 EMT53803.1 - 9.3e-11 41.3 0.1 9.3e-11 41.3 0.1 1.9 2 0 0 2 2 1 1 Bacterial regulatory protein, Fis family PAS_4 PF08448.10 EMT53803.1 - 1.6e-08 34.7 0.0 4.2e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EMT53803.1 - 2.6e-08 34.1 0.2 9.1e-08 32.3 0.1 2.0 2 0 0 2 2 2 1 PAS domain AAA_5 PF07728.14 EMT53803.1 - 4.7e-07 29.9 0.1 1.9e-06 27.9 0.0 2.1 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) HTH_30 PF13556.6 EMT53803.1 - 1.5e-06 27.9 0.0 4.9e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain PAS PF00989.25 EMT53803.1 - 2.3e-05 24.3 0.0 7e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 PAS fold Mg_chelatase PF01078.21 EMT53803.1 - 0.00018 20.9 0.0 0.0098 15.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EMT53803.1 - 0.0011 19.4 0.1 0.0023 18.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain PAS_7 PF12860.7 EMT53803.1 - 0.0043 17.2 0.0 0.0094 16.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold AAA PF00004.29 EMT53803.1 - 0.0057 17.1 0.0 0.014 15.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_1 PF00126.27 EMT53803.1 - 0.0068 16.3 0.0 0.032 14.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family AAA_3 PF07726.11 EMT53803.1 - 0.0089 15.9 0.0 0.033 14.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) H_kinase_N PF12282.8 EMT53803.1 - 0.012 15.5 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 Signal transduction histidine kinase MCM PF00493.23 EMT53803.1 - 0.018 14.1 0.3 0.047 12.8 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain DUF815 PF05673.13 EMT53803.1 - 0.093 11.9 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AA_permease PF00324.21 EMT53804.1 - 1.6e-123 412.8 40.0 2e-123 412.5 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMT53804.1 - 4.2e-37 128.0 42.4 5.4e-37 127.6 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EMT53804.1 - 0.0019 18.2 6.0 0.0019 18.2 6.0 3.7 3 1 0 3 3 3 1 C-terminus of AA_permease UPF0182 PF03699.13 EMT53804.1 - 7.5 4.5 9.7 14 3.7 9.2 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF1265 PF06887.14 EMT53805.1 - 0.048 13.6 0.1 0.1 12.6 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1265) MFS_1 PF07690.16 EMT53806.1 - 1.2e-34 119.8 46.0 1.8e-19 69.9 27.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT53806.1 - 3e-10 39.5 26.1 8.9e-10 38.0 26.1 1.7 1 1 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.24 EMT53806.1 - 3.7e-09 36.0 28.0 2.1e-07 30.2 10.5 2.3 2 1 1 3 3 3 2 Sugar (and other) transporter Nuc_H_symport PF03825.16 EMT53806.1 - 3.4e-05 23.0 7.5 3.4e-05 23.0 7.5 2.2 2 0 0 2 2 2 1 Nucleoside H+ symporter DUF2371 PF10177.9 EMT53806.1 - 8 6.6 7.6 7.7 6.7 1.4 3.7 3 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) LysR_substrate PF03466.20 EMT53807.1 - 1.1e-31 109.8 0.0 1.5e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT53807.1 - 5.3e-21 74.3 0.6 4.1e-20 71.5 0.2 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 EMT53807.1 - 0.00044 19.8 0.0 0.38 10.3 0.0 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_30 PF13556.6 EMT53807.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain MarR PF01047.22 EMT53807.1 - 0.08 12.9 0.2 0.25 11.3 0.2 1.8 1 0 0 1 1 1 0 MarR family PAP2 PF01569.21 EMT53808.1 - 3.7e-19 68.9 8.1 3.7e-19 68.9 8.1 2.6 1 1 1 2 2 2 2 PAP2 superfamily PAP2_3 PF14378.6 EMT53808.1 - 1.3e-05 25.0 7.2 1.3e-05 25.0 7.2 2.3 2 1 1 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 EMT53808.1 - 4.3 8.0 5.9 1.2 9.7 1.6 2.1 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF188 PF02639.14 EMT53809.1 - 1.9e-34 118.2 0.0 2.1e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 T3SS_HrpK1 PF16937.5 EMT53809.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system translocator protein, HrpF Myosin_tail_1 PF01576.19 EMT53810.1 - 0.13 10.1 0.1 0.15 9.9 0.1 1.0 1 0 0 1 1 1 0 Myosin tail Peptidase_S8 PF00082.22 EMT53811.1 - 6.5e-49 166.8 4.4 1e-46 159.6 4.4 2.1 1 1 0 1 1 1 1 Subtilase family Asparaginase_C PF17763.1 EMT53811.1 - 0.00095 19.4 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain SpoVIF PF14069.6 EMT53812.1 - 2.2e-09 36.9 11.6 2.8e-09 36.6 11.6 1.1 1 0 0 1 1 1 1 Stage VI sporulation protein F DUF1002 PF06207.11 EMT53812.1 - 0.0057 16.2 3.8 0.0064 16.1 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1002) UPF0154 PF03672.13 EMT53812.1 - 0.0072 16.3 0.6 0.0072 16.3 0.6 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0154) Efg1 PF10153.9 EMT53812.1 - 0.026 14.9 10.1 0.031 14.6 10.1 1.0 1 0 0 1 1 1 0 rRNA-processing protein Efg1 DUF5431 PF17496.2 EMT53812.1 - 0.033 14.3 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5431) DUF4795 PF16043.5 EMT53812.1 - 0.054 13.1 5.6 0.086 12.4 5.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PrkA PF06798.12 EMT53812.1 - 0.06 13.0 2.6 0.065 12.9 2.6 1.0 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain Ribosomal_L50 PF10501.9 EMT53812.1 - 0.071 13.3 5.1 0.098 12.8 5.1 1.2 1 0 0 1 1 1 0 Ribosomal subunit 39S TFA2_Winged_2 PF18121.1 EMT53812.1 - 0.16 11.7 5.4 0.79 9.5 0.3 2.2 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 DUF3708 PF12501.8 EMT53812.1 - 0.21 11.3 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter YitT_membrane PF02588.15 EMT53813.1 - 2e-07 30.6 14.0 2.5e-07 30.3 14.0 1.1 1 0 0 1 1 1 1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 RNA_lig_T4_1 PF09511.10 EMT53814.1 - 0.073 12.9 0.0 0.073 12.9 0.0 1.1 1 0 0 1 1 1 0 RNA ligase Lactamase_B_2 PF12706.7 EMT53815.1 - 1.1e-23 83.9 0.0 4.9e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMT53815.1 - 1.4e-07 31.7 0.6 4.6e-07 30.0 0.1 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 EMT53815.1 - 4.3e-07 29.5 0.0 7.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 tRNase Z endonuclease PDEase_II PF02112.15 EMT53815.1 - 0.23 10.5 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II NMT1_2 PF13379.6 EMT53816.1 - 2.5e-23 83.1 0.0 3.8e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 EMT53816.1 - 4.2e-22 79.2 0.4 5.4e-22 78.8 0.4 1.1 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 EMT53816.1 - 0.0036 16.9 0.1 0.0056 16.3 0.1 1.4 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein VitK2_biosynth PF02621.14 EMT53816.1 - 0.17 11.3 0.0 1 8.8 0.0 1.9 2 0 0 2 2 2 0 Menaquinone biosynthesis ABC_tran PF00005.27 EMT53817.1 - 3.1e-33 115.2 0.0 4.3e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT53817.1 - 3.6e-08 33.6 0.8 0.0058 16.5 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EMT53817.1 - 3.5e-05 24.2 0.0 0.00016 22.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT53817.1 - 0.00018 21.9 0.0 0.00026 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMT53817.1 - 0.00067 19.6 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EMT53817.1 - 0.00088 19.6 0.1 0.0016 18.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT53817.1 - 0.0046 16.7 0.2 0.044 13.5 0.0 2.3 2 1 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EMT53817.1 - 0.0055 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMT53817.1 - 0.0086 15.8 0.0 0.079 12.6 0.0 1.9 1 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 EMT53817.1 - 0.0091 15.5 0.0 2.6 7.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 EMT53817.1 - 0.0094 15.9 0.2 0.031 14.3 0.1 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EMT53817.1 - 0.012 16.1 0.0 0.02 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMT53817.1 - 0.016 15.2 0.8 0.043 13.7 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EMT53817.1 - 0.02 15.2 0.6 0.041 14.1 0.5 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EMT53817.1 - 0.02 14.3 0.0 0.099 12.0 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EMT53817.1 - 0.029 14.1 0.1 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 EMT53817.1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.5 2 0 0 2 2 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 EMT53817.1 - 0.033 14.1 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EMT53817.1 - 0.034 14.7 0.0 0.062 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMT53817.1 - 0.038 13.5 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 EMT53817.1 - 0.048 12.8 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 EMT53817.1 - 0.05 13.3 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EMT53817.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 EMT53817.1 - 0.073 13.2 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EMT53817.1 - 0.11 13.0 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.25 EMT53817.1 - 0.12 12.0 0.3 1.1 8.8 0.1 2.1 1 1 1 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 EMT53817.1 - 0.13 12.0 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMT53817.1 - 0.17 12.0 0.4 0.32 11.2 0.4 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EMT53817.1 - 0.2 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 EMT53817.1 - 0.2 11.3 0.1 0.38 10.3 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain BPD_transp_1 PF00528.22 EMT53818.1 - 4.2e-22 78.8 19.6 4.2e-22 78.8 19.6 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.21 EMT53818.1 - 1.1 9.7 29.8 0.12 12.8 8.5 2.7 3 0 0 3 3 3 0 FtsX-like permease family TPR_14 PF13428.6 EMT53819.1 - 7.6e-12 45.0 4.9 5.1e-05 23.8 0.0 5.0 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMT53819.1 - 3.3e-10 39.4 3.3 0.17 12.1 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMT53819.1 - 1.4e-09 37.3 7.8 0.021 14.9 0.0 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMT53819.1 - 3.2e-09 37.2 3.1 0.00039 20.9 0.2 4.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EMT53819.1 - 5e-07 29.3 2.1 0.31 10.9 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMT53819.1 - 6.1e-06 26.8 3.3 0.01 16.5 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EMT53819.1 - 0.00023 20.5 4.3 0.042 13.1 1.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMT53819.1 - 0.00074 19.8 3.1 0.045 14.0 0.5 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMT53819.1 - 0.0016 18.7 1.1 1.2 9.4 0.1 3.2 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EMT53819.1 - 0.0023 18.2 3.1 0.27 11.7 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EMT53819.1 - 0.0038 16.7 2.2 0.046 13.1 0.0 3.0 2 1 2 4 4 4 1 Coatomer epsilon subunit TPR_4 PF07721.14 EMT53819.1 - 0.0044 17.5 0.3 3.1 8.7 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMT53819.1 - 0.0077 16.2 2.5 7.4 6.9 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMT53819.1 - 0.014 16.0 10.3 0.14 12.8 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EMT53819.1 - 0.02 15.2 3.3 2.5 8.5 0.2 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Takusan PF04822.13 EMT53819.1 - 0.02 14.7 4.3 0.03 14.2 0.6 2.3 2 0 0 2 2 2 0 Takusan DUF3808 PF10300.9 EMT53819.1 - 0.031 13.0 2.6 0.28 9.9 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3808) Protoglobin PF11563.8 EMT53819.1 - 0.068 13.1 0.1 0.22 11.4 0.1 1.9 1 0 0 1 1 1 0 Protoglobin ArgJ PF01960.18 EMT53819.1 - 0.16 10.7 0.1 0.32 9.7 0.0 1.5 2 0 0 2 2 2 0 ArgJ family YfdX PF10938.8 EMT53819.1 - 0.19 11.7 1.5 14 5.6 0.6 2.9 2 1 0 2 2 2 0 YfdX protein TPR_10 PF13374.6 EMT53819.1 - 1 9.4 6.2 2.4 8.2 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat SH3_12 PF18129.1 EMT53820.1 - 0.00086 19.4 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Xrn1 SH3-like domain DUF2621 PF11084.8 EMT53821.1 - 1.6e-69 232.2 0.2 1.9e-69 232.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2621) PCP_red PF08369.10 EMT53821.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit DUF2207 PF09972.9 EMT53821.1 - 0.026 13.3 1.5 0.26 10.0 1.5 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) AAA_5 PF07728.14 EMT53823.1 - 1.6e-10 41.1 0.0 2.8e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) CobT_C PF11775.8 EMT53823.1 - 6.9e-06 25.9 0.2 2.1e-05 24.3 0.1 1.8 1 1 1 2 2 2 1 Cobalamin biosynthesis protein CobT VWA domain AAA_3 PF07726.11 EMT53823.1 - 9.3e-05 22.3 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 EMT53823.1 - 0.00013 21.0 0.9 0.16 10.9 0.0 2.7 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 EMT53823.1 - 0.0014 18.7 0.0 0.0062 16.5 0.0 2.1 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EMT53823.1 - 0.0029 18.1 2.5 0.01 16.4 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 EMT53823.1 - 0.0042 17.5 0.0 0.015 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EMT53823.1 - 0.0078 16.6 0.0 0.16 12.4 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMT53823.1 - 0.017 15.4 0.0 0.073 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain VWA_2 PF13519.6 EMT53823.1 - 0.028 15.1 0.2 0.48 11.1 0.1 2.7 2 0 0 2 2 2 0 von Willebrand factor type A domain MMR_HSR1_C PF08438.10 EMT53823.1 - 0.051 14.2 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 GTPase of unknown function C-terminal NACHT PF05729.12 EMT53823.1 - 0.051 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 EMT53823.1 - 0.084 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EMT53823.1 - 0.093 12.5 0.2 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein MFS_1 PF07690.16 EMT53824.1 - 3.8e-25 88.6 39.9 1.9e-16 59.9 14.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT53824.1 - 3e-19 68.8 24.9 3.5e-19 68.6 24.9 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector Rhodanese PF00581.20 EMT53826.1 - 3.4e-36 124.0 0.0 2.3e-20 73.1 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain HATPase_c PF02518.26 EMT53827.1 - 6.7e-20 71.7 0.0 1.6e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT53827.1 - 3.4e-10 39.8 0.0 1.4e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EMT53827.1 - 0.0079 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase sCache_like PF16736.5 EMT53827.1 - 0.041 14.0 0.0 13 5.9 0.0 2.6 2 0 0 2 2 2 0 Single Cache-like HATPase_c_2 PF13581.6 EMT53827.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain TFIID-18kDa PF02269.16 EMT53827.1 - 0.14 12.2 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Response_reg PF00072.24 EMT53828.1 - 1.2e-24 86.7 0.1 1.7e-24 86.2 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EMT53828.1 - 1.5e-21 76.2 0.0 3.2e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF418 PF04235.12 EMT53829.1 - 7.7e-43 146.2 7.0 7.7e-43 146.2 7.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF418) Acyl_transf_3 PF01757.22 EMT53829.1 - 5.3e-08 32.3 26.5 8.6e-06 25.0 16.8 2.3 1 1 1 2 2 2 2 Acyltransferase family Exo_endo_phos PF03372.23 EMT53831.1 - 2.4e-25 89.4 0.0 2.8e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EMT53831.1 - 1.5e-05 24.8 0.0 5.9e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF817 PF05675.12 EMT53832.1 - 2.5e-106 354.7 16.4 2.9e-106 354.5 16.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF817) MFS_1 PF07690.16 EMT53833.1 - 7.8e-36 123.7 51.5 3.3e-27 95.4 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EMT53833.1 - 0.00047 19.6 26.0 0.00068 19.0 26.0 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF2614 PF11023.8 EMT53833.1 - 0.012 15.7 0.0 0.012 15.7 0.0 3.1 3 0 0 3 3 3 0 Zinc-ribbon containing domain Nuc_H_symport PF03825.16 EMT53833.1 - 0.024 13.7 19.0 0.03 13.3 18.6 1.4 1 1 0 1 1 1 0 Nucleoside H+ symporter MFS_1_like PF12832.7 EMT53833.1 - 1.3 7.8 27.2 1.4 7.7 11.6 2.1 1 1 1 2 2 2 0 MFS_1 like family DUF997 PF06196.12 EMT53834.1 - 0.019 15.0 2.3 0.05 13.6 2.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF997) GTP_EFTU PF00009.27 EMT53835.1 - 9.2e-53 178.7 0.0 1.4e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 EMT53835.1 - 6.1e-45 152.3 0.3 1e-44 151.6 0.3 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 EMT53835.1 - 6.5e-07 29.6 0.0 1.3e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMT53835.1 - 6e-06 26.3 0.1 1.4e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.6 EMT53835.1 - 0.0032 17.5 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II FeoB_N PF02421.18 EMT53835.1 - 0.034 13.7 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.22 EMT53835.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Ras family SRPRB PF09439.10 EMT53835.1 - 0.15 11.5 0.1 1 8.8 0.1 2.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Peptidase_M32 PF02074.15 EMT53836.1 - 1.2e-195 651.0 0.1 1.3e-195 650.8 0.1 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase UDG PF03167.19 EMT53837.1 - 1.7e-18 67.1 0.0 2e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily FMN_red PF03358.15 EMT53838.1 - 2.8e-36 124.6 0.0 3.3e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EMT53838.1 - 4.8e-12 46.0 0.0 6.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold NAD_binding_10 PF13460.6 EMT53839.1 - 5.9e-26 91.5 0.2 6.7e-26 91.3 0.2 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMT53839.1 - 4.1e-08 33.1 1.7 1.5e-07 31.3 1.7 2.0 1 1 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 EMT53839.1 - 0.00011 22.7 0.6 0.00021 21.8 0.6 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EMT53839.1 - 0.00029 21.0 0.7 0.00069 19.7 0.4 1.8 1 1 1 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 EMT53839.1 - 0.00034 20.2 0.1 0.00054 19.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 EMT53839.1 - 0.00073 19.4 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 EMT53839.1 - 0.0078 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EMT53839.1 - 0.019 14.0 0.2 0.094 11.8 0.1 2.0 2 1 1 3 3 3 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 EMT53839.1 - 0.019 15.4 1.5 0.44 11.0 0.8 2.7 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EMT53839.1 - 0.044 13.7 0.3 0.061 13.2 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FTCD_C PF04961.12 EMT53839.1 - 0.051 13.3 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase NAD_binding_2 PF03446.15 EMT53839.1 - 0.073 13.2 0.1 0.098 12.8 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase WD40_3 PF15911.5 EMT53839.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat Rrf2 PF02082.20 EMT53840.1 - 2.4e-22 79.1 0.4 7.2e-22 77.5 0.1 1.8 2 0 0 2 2 2 1 Transcriptional regulator HrcA_DNA-bdg PF03444.15 EMT53840.1 - 0.0004 20.0 0.0 0.00073 19.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_Crp_2 PF13545.6 EMT53840.1 - 0.00041 20.3 0.0 0.00075 19.4 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain GntR PF00392.21 EMT53840.1 - 0.0023 17.6 0.1 0.044 13.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family TFIIE_alpha PF02002.17 EMT53840.1 - 0.06 13.2 0.1 0.36 10.7 0.0 2.2 3 0 0 3 3 3 0 TFIIE alpha subunit TrmB PF01978.19 EMT53840.1 - 0.13 12.1 0.0 0.29 11.1 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB His_Phos_1 PF00300.22 EMT53841.1 - 1.1e-26 93.7 0.0 1.4e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) dNK PF01712.19 EMT53842.1 - 6.2e-07 29.5 0.1 0.0053 16.6 0.0 2.3 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_18 PF13238.6 EMT53842.1 - 2.2e-06 28.2 0.2 2.2e-06 28.2 0.2 2.1 2 1 0 2 2 1 1 AAA domain SKI PF01202.22 EMT53842.1 - 3e-05 24.2 0.0 5.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase PRK PF00485.18 EMT53842.1 - 0.00016 21.5 0.3 0.066 13.0 0.0 2.2 1 1 1 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EMT53842.1 - 0.0015 18.7 0.0 0.0066 16.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EMT53842.1 - 0.0044 17.5 0.0 0.0076 16.7 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EMT53842.1 - 0.0054 17.2 0.0 0.011 16.2 0.0 1.6 2 0 0 2 2 1 1 ABC transporter AAA_22 PF13401.6 EMT53842.1 - 0.0088 16.3 0.1 0.014 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EMT53842.1 - 0.0091 16.2 0.3 0.026 14.8 0.2 1.9 2 1 0 2 2 1 1 AAA domain Cytidylate_kin2 PF13189.6 EMT53842.1 - 0.01 16.0 0.0 0.038 14.1 0.0 2.1 1 1 0 1 1 1 0 Cytidylate kinase-like family Cytidylate_kin PF02224.18 EMT53842.1 - 0.013 15.2 0.3 1.3 8.7 0.0 2.2 1 1 0 2 2 2 0 Cytidylate kinase TsaE PF02367.17 EMT53842.1 - 0.018 15.1 0.1 0.058 13.4 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 EMT53842.1 - 0.025 13.7 0.2 0.87 8.7 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.12 EMT53842.1 - 0.033 13.5 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PduV-EutP PF10662.9 EMT53842.1 - 0.037 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EMT53842.1 - 0.058 13.4 0.1 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EMT53842.1 - 0.076 13.4 2.3 0.14 12.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EMT53842.1 - 0.077 12.2 0.1 0.087 12.0 0.1 1.3 1 1 0 1 1 1 0 NB-ARC domain MobB PF03205.14 EMT53842.1 - 0.1 12.5 0.1 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activ_2 PF14532.6 EMT53842.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain CoaE PF01121.20 EMT53842.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase NACHT PF05729.12 EMT53842.1 - 0.38 10.7 0.0 0.38 10.7 0.0 1.8 3 0 0 3 3 2 0 NACHT domain S-methyl_trans PF02574.16 EMT53843.1 - 2.1e-53 181.9 0.0 1.1e-52 179.5 0.0 1.9 2 0 0 2 2 2 1 Homocysteine S-methyltransferase MTHFR PF02219.17 EMT53843.1 - 1.1e-28 100.4 0.0 1.9e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PEP_mutase PF13714.6 EMT53843.1 - 0.00023 20.7 0.1 0.04 13.4 0.0 3.5 2 1 1 3 3 3 1 Phosphoenolpyruvate phosphomutase HrpB1_HrpK PF09613.10 EMT53843.1 - 0.13 11.9 0.7 0.82 9.3 0.1 2.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) S-methyl_trans PF02574.16 EMT53844.1 - 1.2e-76 258.1 0.0 1.9e-76 257.4 0.0 1.3 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.17 EMT53844.1 - 1.6e-60 204.9 0.0 2.8e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.22 EMT53844.1 - 6.3e-42 143.9 0.0 1.2e-41 143.0 0.0 1.5 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.17 EMT53844.1 - 1.5e-21 76.6 0.2 1.5e-21 76.6 0.2 2.5 3 0 0 3 3 3 1 B12 binding domain B12-binding PF02310.19 EMT53844.1 - 2.3e-21 76.1 0.2 1.4e-20 73.5 0.1 2.6 2 0 0 2 2 2 1 B12 binding domain CdhD PF03599.16 EMT53844.1 - 0.00043 19.1 0.0 0.0008 18.2 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit MtrH PF02007.18 EMT53844.1 - 0.032 13.3 0.0 0.072 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit DD_K PF12121.8 EMT53844.1 - 0.16 12.1 0.2 2.9 8.1 0.1 2.6 2 0 0 2 2 2 0 Dermaseptin YjcZ_2 PF09680.10 EMT53845.1 - 1.2e-09 37.7 6.6 1.4e-09 37.4 6.6 1.1 1 0 0 1 1 1 1 Family of unknown function Pelovaterin PF17859.1 EMT53845.1 - 0.025 14.8 0.0 0.028 14.7 0.0 1.0 1 0 0 1 1 1 0 Pelovaterin Cass2 PF14526.6 EMT53846.1 - 9.9e-28 97.2 0.2 1.5e-27 96.6 0.2 1.3 1 0 0 1 1 1 1 Integron-associated effector binding protein HTH_AraC PF00165.23 EMT53846.1 - 2e-21 75.5 0.5 9.3e-11 41.5 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EMT53846.1 - 1.4e-20 73.3 1.7 1.4e-20 73.3 1.7 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain GyrI-like PF06445.15 EMT53846.1 - 1.5e-19 70.8 0.1 2.1e-19 70.4 0.1 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain DUF2851 PF11013.8 EMT53846.1 - 0.045 12.7 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2851) tRNA-synt_1d PF00750.19 EMT53848.1 - 7.8e-98 327.6 0.2 1.1e-97 327.2 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EMT53848.1 - 1.7e-32 112.1 0.0 5e-32 110.6 0.0 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EMT53848.1 - 1.1e-16 61.2 0.3 5.3e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain YppF PF14178.6 EMT53848.1 - 0.0077 16.1 0.0 0.22 11.4 0.2 2.6 2 0 0 2 2 2 1 YppF-like protein PCuAC PF04314.13 EMT53849.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.5 1 1 0 1 1 1 0 Copper chaperone PCu(A)C AP_endonuc_2 PF01261.24 EMT53850.1 - 1.3e-27 96.7 0.1 1.6e-27 96.4 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Acetyltransf_3 PF13302.7 EMT53851.1 - 8.6e-14 52.4 0.0 1e-13 52.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT53851.1 - 2.8e-13 50.1 0.0 3.5e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT53851.1 - 3.4e-10 39.9 0.0 3.9e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT53851.1 - 3.9e-07 30.4 0.0 5.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT53851.1 - 1e-06 28.9 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT53851.1 - 9.1e-06 25.6 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EMT53851.1 - 0.0005 20.1 0.0 0.0014 18.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EMT53851.1 - 0.054 13.0 0.1 0.093 12.2 0.1 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase TetR_C_5 PF08360.11 EMT53852.1 - 4.2e-29 101.4 0.0 7.5e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 QacR-like protein, C-terminal region TetR_N PF00440.23 EMT53852.1 - 5.4e-18 64.5 0.5 1e-17 63.6 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EMT53852.1 - 4e-06 27.1 0.0 3.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_27 PF17935.1 EMT53852.1 - 0.043 13.9 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 EMT53853.1 - 3.2e-29 102.0 29.8 2.2e-22 79.5 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT53853.1 - 2.5e-25 88.9 18.1 3.2e-25 88.5 18.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector ExbD PF02472.16 EMT53853.1 - 0.16 12.2 0.1 0.44 10.7 0.1 1.7 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Serinc PF03348.15 EMT53853.1 - 5.9 5.7 10.4 1.4 7.8 0.3 2.5 2 1 0 2 2 2 0 Serine incorporator (Serinc) Usp PF00582.26 EMT53854.1 - 9.9e-50 168.7 0.0 1.8e-26 93.3 0.0 2.0 2 0 0 2 2 2 2 Universal stress protein family DXP_reductoisom PF02670.16 EMT53854.1 - 0.0031 18.2 0.1 0.21 12.3 0.0 2.9 3 0 0 3 3 3 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase RDV-p3 PF09231.10 EMT53854.1 - 0.21 9.3 0.0 0.35 8.5 0.0 1.3 1 0 0 1 1 1 0 Rice dwarf virus p3 HD_5 PF13487.6 EMT53855.1 - 1.4e-09 38.1 0.0 6e-09 36.0 0.1 2.0 2 0 0 2 2 2 1 HD domain HD PF01966.22 EMT53855.1 - 2.4e-08 34.2 0.2 4.2e-08 33.4 0.2 1.4 1 0 0 1 1 1 1 HD domain SSF PF00474.17 EMT53857.1 - 9.1e-109 364.0 41.6 1.1e-108 363.7 41.6 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2818 PF10993.8 EMT53857.1 - 0.067 13.8 0.4 0.067 13.8 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2818) DUF4244 PF14029.6 EMT53857.1 - 0.11 12.0 6.3 2.9 7.4 2.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4244) SSF PF00474.17 EMT53858.1 - 4.7e-124 414.3 42.4 6.2e-124 413.9 42.4 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family AA_permease_2 PF13520.6 EMT53858.1 - 8.3e-05 21.6 50.2 8.3e-05 21.6 50.2 1.8 1 1 1 2 2 2 1 Amino acid permease DUF2818 PF10993.8 EMT53858.1 - 0.055 14.0 0.1 0.055 14.0 0.1 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF2818) DUF485 PF04341.12 EMT53859.1 - 1.9e-24 85.4 2.8 2.5e-24 85.0 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF485 LytTR PF04397.15 EMT53860.1 - 4.1e-27 94.3 0.2 1.3e-26 92.7 0.0 1.9 2 0 0 2 2 2 1 LytTr DNA-binding domain Response_reg PF00072.24 EMT53860.1 - 2.9e-23 82.2 0.1 4.8e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain MTD PF01993.18 EMT53860.1 - 0.062 12.6 0.2 0.42 9.9 0.0 2.0 1 1 1 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase 5TM-5TMR_LYT PF07694.12 EMT53861.1 - 1.2e-44 151.8 14.0 2.2e-44 151.0 14.0 1.4 1 0 0 1 1 1 1 5TMR of 5TMR-LYT His_kinase PF06580.13 EMT53861.1 - 5.6e-23 81.1 1.4 1.4e-22 79.7 1.4 1.7 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 EMT53861.1 - 1e-11 45.3 0.0 2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 EMT53861.1 - 4.9e-11 43.1 0.0 9.8e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 EMT53861.1 - 1.2e-05 25.4 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor HATPase_c_2 PF13581.6 EMT53861.1 - 0.001 19.0 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain GAF_2 PF13185.6 EMT53861.1 - 0.0016 18.7 0.0 0.0038 17.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain Asn_synthase PF00733.21 EMT53862.1 - 2e-94 317.2 0.1 2.6e-94 316.8 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EMT53862.1 - 3.5e-48 162.6 0.0 6e-48 161.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EMT53862.1 - 1.6e-39 135.2 0.0 2.9e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EMT53862.1 - 0.0004 19.9 0.0 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Aluminium induced protein Hexapep PF00132.24 EMT53864.1 - 9.6e-20 69.5 8.9 2.8e-07 30.0 0.2 4.6 4 1 1 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMT53864.1 - 0.00048 19.8 9.8 0.11 12.3 1.0 3.8 1 1 3 4 4 4 4 Hexapeptide repeat of succinyl-transferase Gas_vesicle PF00741.18 EMT53864.1 - 0.042 14.0 3.4 0.042 14.0 0.6 2.2 2 0 0 2 2 2 0 Gas vesicle protein DUF4954 PF16314.5 EMT53864.1 - 0.073 11.2 0.9 0.092 10.9 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EMT53864.1 - 0.11 11.4 0.0 0.3 10.0 0.0 1.5 1 1 0 1 1 1 0 L-fucokinase DUF1385 PF07136.11 EMT53865.1 - 3.5e-10 39.6 0.1 2.6e-09 36.7 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1385) YfkB PF08756.10 EMT53866.1 - 2.5e-72 241.6 0.1 3.8e-72 241.0 0.1 1.3 1 0 0 1 1 1 1 YfkB-like domain Radical_SAM PF04055.21 EMT53866.1 - 2.1e-10 41.2 0.0 9e-10 39.2 0.0 1.9 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 EMT53866.1 - 3.1e-06 27.5 0.0 8.5e-06 26.1 0.0 1.7 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EMT53866.1 - 1e-05 25.6 0.0 2.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain SASP PF00269.20 EMT53867.1 - 1.2e-21 76.5 2.1 4.7e-21 74.6 2.1 1.9 1 1 0 1 1 1 1 Small, acid-soluble spore proteins, alpha/beta type CN_hydrolase PF00795.22 EMT53869.1 - 1.4e-47 162.2 0.0 1.6e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_1 PF01344.25 EMT53869.1 - 0.0044 16.6 0.3 0.035 13.7 0.0 2.6 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 EMT53869.1 - 0.021 15.1 0.7 1.2 9.5 0.1 2.8 2 1 0 2 2 2 0 Galactose oxidase, central domain LysM PF01476.20 EMT53870.1 - 1.8e-16 59.9 0.2 4.1e-16 58.8 0.1 1.6 2 0 0 2 2 2 1 LysM domain DUF3782 PF12644.7 EMT53870.1 - 0.0045 17.1 1.9 4.2 7.6 3.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3782) Fib_alpha PF08702.10 EMT53870.1 - 0.0053 17.0 0.1 0.007 16.6 0.1 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Tropomyosin PF00261.20 EMT53870.1 - 0.013 14.9 2.4 0.017 14.5 2.4 1.1 1 0 0 1 1 1 0 Tropomyosin CLZ PF16526.5 EMT53870.1 - 0.017 15.5 1.0 0.046 14.1 1.1 1.6 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc29 PF17082.5 EMT53870.1 - 0.025 14.4 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF2802 PF10975.8 EMT53870.1 - 0.032 14.4 0.2 6.2 7.0 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) DHR10 PF18595.1 EMT53870.1 - 0.033 14.2 0.6 0.043 13.9 0.6 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain BLOC1_2 PF10046.9 EMT53870.1 - 0.047 14.0 0.0 0.065 13.5 0.0 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 EMT53870.1 - 0.051 13.7 0.1 0.072 13.3 0.1 1.2 1 0 0 1 1 1 0 Tropomyosin like Laminin_II PF06009.12 EMT53870.1 - 0.054 13.5 0.0 0.067 13.2 0.0 1.1 1 0 0 1 1 1 0 Laminin Domain II SlyX PF04102.12 EMT53870.1 - 0.058 14.0 0.4 0.1 13.2 0.4 1.4 1 0 0 1 1 1 0 SlyX XhlA PF10779.9 EMT53870.1 - 0.078 13.2 1.9 0.22 11.7 2.0 1.7 1 1 0 1 1 1 0 Haemolysin XhlA DivIC PF04977.15 EMT53870.1 - 0.11 12.3 0.3 0.18 11.6 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator SOAR PF16533.5 EMT53870.1 - 0.12 12.3 0.2 0.17 11.9 0.2 1.1 1 0 0 1 1 1 0 STIM1 Orai1-activating region FlaC_arch PF05377.11 EMT53870.1 - 0.13 12.6 0.2 0.22 11.9 0.2 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 EMT53870.1 - 0.22 11.5 0.0 0.29 11.1 0.0 1.1 1 0 0 1 1 1 0 Prefoldin subunit Trimer_CC PF08954.11 EMT53870.1 - 0.28 10.8 6.0 0.63 9.7 6.0 1.6 1 1 0 1 1 1 0 Trimerisation motif LegC3_N PF18654.1 EMT53870.1 - 1.5 8.0 5.1 1.9 7.7 5.1 1.1 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain HipA_C PF07804.12 EMT53871.1 - 0.017 14.8 0.0 0.23 11.1 0.0 2.2 1 1 0 1 1 1 0 HipA-like C-terminal domain PI3_PI4_kinase PF00454.27 EMT53871.1 - 0.019 14.8 0.0 0.061 13.1 0.0 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase CotH PF08757.11 EMT53871.1 - 0.045 13.3 0.3 0.26 10.7 0.0 2.1 2 1 0 2 2 2 0 CotH kinase protein Fumerase PF05681.14 EMT53872.1 - 1.3e-73 247.8 0.0 1.7e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 EMT53872.1 - 2e-62 210.2 0.1 3e-62 209.6 0.1 1.3 1 0 0 1 1 1 1 Fumarase C-terminus Beta_propel PF09826.9 EMT53873.1 - 2.2e-181 604.2 3.7 2.6e-181 604.0 3.7 1.0 1 0 0 1 1 1 1 Beta propeller domain TPR_2 PF07719.17 EMT53874.1 - 8.1e-11 41.2 3.0 0.055 13.6 0.1 5.1 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EMT53874.1 - 3.6e-09 36.1 3.6 0.0094 15.7 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMT53874.1 - 1.6e-07 31.5 4.1 0.049 13.9 0.2 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMT53874.1 - 1.6e-06 27.9 4.3 0.64 10.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMT53874.1 - 8.3e-06 25.5 1.8 1.8 8.8 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMT53874.1 - 2.4e-05 24.4 1.8 0.0064 16.7 0.1 2.3 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EMT53874.1 - 9.6e-05 22.8 0.1 0.19 12.3 0.0 3.1 2 1 3 5 5 5 2 Tetratricopeptide repeat HemY_N PF07219.13 EMT53874.1 - 0.00011 22.3 0.3 0.0057 16.8 0.0 2.5 2 0 0 2 2 2 1 HemY protein N-terminus TPR_14 PF13428.6 EMT53874.1 - 0.00014 22.4 0.5 0.78 10.7 0.1 4.3 3 2 2 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMT53874.1 - 0.00039 20.9 2.1 5.8 7.8 0.1 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMT53874.1 - 0.00072 20.2 0.0 0.33 11.6 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 EMT53874.1 - 0.00083 19.3 0.1 0.57 10.2 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EMT53874.1 - 0.0019 18.0 0.7 0.24 11.3 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMT53874.1 - 0.0019 17.8 3.7 6.1 6.6 0.1 4.0 3 1 1 4 4 4 1 TPR repeat TPR_20 PF14561.6 EMT53874.1 - 0.0028 18.0 0.1 3.9 7.9 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMT53874.1 - 0.035 14.5 1.2 11 6.6 0.0 3.5 5 0 0 5 5 3 0 Tetratricopeptide repeat Paf67 PF10255.9 EMT53874.1 - 0.085 11.8 0.3 0.31 10.0 0.2 1.7 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 TPR_4 PF07721.14 EMT53874.1 - 0.091 13.4 0.0 61 4.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Lactamase_B PF00753.27 EMT53875.1 - 3.2e-14 53.4 3.6 3.1e-13 50.2 3.6 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMT53875.1 - 0.005 16.4 0.5 0.01 15.4 0.5 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ABC_tran PF00005.27 EMT53876.1 - 1.1e-30 107.0 0.0 1.5e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT53876.1 - 5.7e-11 42.8 0.3 5.9e-05 23.0 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMT53876.1 - 0.0016 18.9 0.0 0.0023 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT53876.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EMT53876.1 - 0.0041 17.4 0.3 3.8 7.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EMT53876.1 - 0.0057 16.1 0.0 0.096 12.1 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT53876.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EMT53876.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EMT53876.1 - 0.022 14.5 0.0 0.035 13.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMT53876.1 - 0.036 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMT53876.1 - 0.039 14.3 0.2 0.1 13.0 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EMT53876.1 - 0.067 13.6 0.0 0.2 12.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EMT53876.1 - 0.079 12.9 0.2 0.22 11.4 0.1 1.7 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 EMT53876.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF3584 PF12128.8 EMT53876.1 - 0.13 9.8 0.0 0.18 9.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Roc PF08477.13 EMT53876.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EMT53876.1 - 0.2 11.2 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EMT53876.1 - 0.21 11.7 0.0 0.51 10.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase EAL PF00563.20 EMT53877.1 - 5.5e-80 268.3 0.0 8.5e-80 267.7 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 EMT53877.1 - 1.9e-47 161.0 0.0 3.4e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MASE3 PF17159.4 EMT53877.1 - 3e-46 157.9 12.1 4.6e-46 157.3 12.1 1.3 1 0 0 1 1 1 1 Membrane-associated sensor domain PAS PF00989.25 EMT53877.1 - 3.7e-10 39.8 0.0 9.5e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EMT53877.1 - 1.9e-09 37.7 0.0 4.4e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EMT53877.1 - 7.8e-07 29.3 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EMT53877.1 - 1.8e-05 24.6 0.0 6.6e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 EMT53877.1 - 0.0041 17.3 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 PAS fold PAS_10 PF13596.6 EMT53877.1 - 0.011 16.3 0.0 0.069 13.8 0.0 2.2 2 0 0 2 2 2 0 PAS domain SpoVT_C PF15714.5 EMT53877.1 - 0.026 14.6 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor DUF4131 PF13567.6 EMT53877.1 - 0.32 10.6 10.2 0.69 9.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) GGDEF PF00990.21 EMT53878.1 - 1.8e-44 151.3 0.1 2.4e-44 150.9 0.1 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 EMT53878.1 - 1.3e-16 60.7 0.0 2.9e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EMT53878.1 - 4e-12 46.1 0.0 2.6e-11 43.5 0.0 2.1 1 1 1 2 2 2 2 PAS fold PAS_4 PF08448.10 EMT53878.1 - 2.8e-10 40.4 0.0 2.7e-09 37.3 0.0 2.3 2 1 2 4 4 4 1 PAS fold PAS_8 PF13188.7 EMT53878.1 - 1e-07 31.8 0.0 7.9e-07 29.0 0.0 2.2 2 1 0 2 2 2 1 PAS domain PAS_3 PF08447.12 EMT53878.1 - 3.1e-07 30.6 0.1 6.2e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 PAS fold EAL PF00563.20 EMT53879.1 - 1.2e-75 254.1 0.0 2.1e-75 253.3 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 EMT53879.1 - 2.2e-54 183.6 0.0 3.8e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MHYT PF03707.16 EMT53879.1 - 2.1e-42 143.1 35.3 1.7e-17 63.3 5.1 4.4 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat PAS_4 PF08448.10 EMT53879.1 - 1.2e-05 25.5 0.0 3.6e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EMT53879.1 - 0.00034 20.8 0.0 0.00089 19.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 EMT53879.1 - 0.00075 19.5 0.0 0.0023 17.9 0.0 1.9 1 0 0 1 1 1 1 PAS domain ING PF12998.7 EMT53879.1 - 0.11 13.1 0.0 0.32 11.6 0.0 1.7 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding GGDEF_2 PF17853.1 EMT53879.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 GGDEF-like domain CMD PF02627.20 EMT53880.1 - 4e-16 58.8 0.0 4.8e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family UvdE PF03851.14 EMT53881.1 - 3.2e-73 246.4 0.0 4e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 UV-endonuclease UvdE Ribosomal_S21 PF01165.20 EMT53881.1 - 0.056 13.2 0.3 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein S21 FXR_C3 PF16097.5 EMT53882.1 - 0.26 12.0 7.4 1.7 9.4 3.9 3.1 1 1 1 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 SQAPI PF16845.5 EMT53882.1 - 5.4 7.4 10.6 17 5.8 0.3 4.0 1 1 2 3 3 3 0 Aspartic acid proteinase inhibitor Lyase_aromatic PF00221.19 EMT53883.1 - 2.9e-204 679.0 8.7 3.3e-204 678.8 8.7 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase MOZART1 PF12554.8 EMT53883.1 - 0.063 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated TIG_plexin PF17960.1 EMT53883.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 TIG domain DUF393 PF04134.12 EMT53884.1 - 3.1e-35 121.9 0.1 3.6e-35 121.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Thioredoxin_6 PF13848.6 EMT53884.1 - 0.069 13.1 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain 4HBT PF03061.22 EMT53885.1 - 2.4e-19 69.5 0.1 3.5e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 EMT53885.1 - 0.0058 17.1 0.0 0.0079 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Ald_Xan_dh_C2 PF02738.18 EMT53885.1 - 0.083 11.3 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase DUF3109 PF11307.8 EMT53886.1 - 3e-09 36.9 0.0 4.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3109) Peptidase_C37 PF05416.12 EMT53886.1 - 0.076 11.5 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Copper-fist PF00649.18 EMT53886.1 - 0.39 10.3 6.8 1 8.9 0.2 2.4 2 0 0 2 2 2 0 Copper fist DNA binding domain Pterin_4a PF01329.19 EMT53888.1 - 2.6e-24 85.2 0.0 2.8e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Methyltransf_25 PF13649.6 EMT53889.1 - 6.4e-19 68.5 0.0 1.3e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT53889.1 - 9.8e-16 57.9 0.0 1.4e-15 57.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT53889.1 - 2.8e-15 56.7 0.0 5.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT53889.1 - 2.9e-14 53.2 0.0 3.9e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EMT53889.1 - 1.1e-10 41.2 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB TPMT PF05724.11 EMT53889.1 - 4.4e-07 29.8 0.0 7.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 EMT53889.1 - 6.9e-07 28.8 0.0 5.6e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMT53889.1 - 9e-07 29.6 0.0 1.5e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMT53889.1 - 1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EMT53889.1 - 2.2e-05 24.7 0.0 3.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 EMT53889.1 - 0.00022 20.6 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EMT53889.1 - 0.00065 18.7 0.1 0.0031 16.5 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1698) Pox_MCEL PF03291.16 EMT53889.1 - 0.0028 16.8 0.4 0.023 13.8 0.1 2.3 2 1 0 2 2 2 1 mRNA capping enzyme PCMT PF01135.19 EMT53889.1 - 0.0043 16.8 0.0 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MethyltransfD12 PF02086.15 EMT53889.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.13 EMT53889.1 - 0.044 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) dNK PF01712.19 EMT53891.1 - 4.5e-61 206.3 0.0 5.2e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 EMT53891.1 - 2.7e-06 28.0 0.0 8.6e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EMT53891.1 - 0.0051 17.0 0.0 0.78 9.8 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase Cytidylate_kin2 PF13189.6 EMT53891.1 - 0.024 14.8 0.0 0.46 10.6 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family CbiA PF01656.23 EMT53891.1 - 0.028 14.5 0.0 0.028 14.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 EMT53891.1 - 0.038 13.7 0.2 0.29 10.8 0.0 2.2 2 1 0 2 2 2 0 Thymidylate kinase TsaE PF02367.17 EMT53891.1 - 0.053 13.5 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EMT53891.1 - 0.14 12.4 0.0 2.7 8.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMT53891.1 - 0.15 12.5 0.2 0.99 9.8 0.0 2.3 3 0 0 3 3 3 0 RNA helicase AAA_17 PF13207.6 EMT53891.1 - 0.16 12.4 0.1 12 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMT53891.1 - 0.21 11.2 0.1 0.58 9.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EMT53892.1 - 7.2e-42 143.6 0.7 8.6e-42 143.3 0.7 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase Cytidylate_kin PF02224.18 EMT53892.1 - 4.4e-06 26.6 0.0 0.089 12.5 0.0 2.2 1 1 1 2 2 2 2 Cytidylate kinase AAA_18 PF13238.6 EMT53892.1 - 2.7e-05 24.7 0.2 8e-05 23.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EMT53892.1 - 0.00036 20.3 1.0 0.0017 18.1 1.0 1.9 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 EMT53892.1 - 0.0038 17.4 0.0 0.01 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EMT53892.1 - 0.014 15.4 0.0 0.034 14.1 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EMT53892.1 - 0.018 14.2 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 EMT53892.1 - 0.019 15.4 0.0 0.023 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EMT53892.1 - 0.022 15.0 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 EMT53892.1 - 0.032 14.4 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase ATPase_2 PF01637.18 EMT53892.1 - 0.042 13.8 0.1 0.07 13.0 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Herpes_TK PF00693.18 EMT53892.1 - 0.044 13.0 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Thymidine kinase from herpesvirus AAA_22 PF13401.6 EMT53892.1 - 0.085 13.1 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EMT53892.1 - 0.13 12.2 0.0 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Radical_SAM PF04055.21 EMT53893.1 - 0.00056 20.3 0.3 0.0087 16.5 0.2 2.7 2 1 0 2 2 2 1 Radical SAM superfamily Rhomboid_N PF12122.8 EMT53894.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease Sigma70_r4_2 PF08281.12 EMT53895.1 - 2.4e-12 46.3 0.0 4.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT53895.1 - 1.2e-11 44.0 0.0 2.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT53895.1 - 2.8e-11 43.0 0.2 6.6e-11 41.8 0.1 1.6 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 EMT53895.1 - 4.5e-10 39.7 0.5 1.1e-09 38.4 0.5 1.6 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 EMT53895.1 - 0.00055 19.6 0.1 0.0012 18.5 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EMT53895.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5643 PF18705.1 EMT53896.1 - 1.7e-26 92.4 1.1 1.4e-19 70.2 0.1 3.3 3 0 0 3 3 3 3 Family of unknown function (DUF5643) DUF4179 PF13786.6 EMT53896.1 - 7.9e-17 61.5 0.0 1.1e-13 51.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4179) Lum_binding PF00677.17 EMT53896.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Lumazine binding domain Phos_pyr_kin PF08543.12 EMT53897.1 - 2.8e-99 331.5 0.1 3.1e-99 331.3 0.1 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EMT53897.1 - 1.7e-13 50.5 0.1 2.1e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HisKA_3 PF07730.13 EMT53898.1 - 1.2e-10 41.7 0.4 1.1e-09 38.6 0.4 2.4 1 1 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 EMT53898.1 - 8e-10 39.2 0.1 3.2e-09 37.3 0.1 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FUSC PF04632.12 EMT53898.1 - 0.063 11.8 1.1 0.072 11.6 1.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4229 PF14012.6 EMT53898.1 - 0.099 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF4728 PF15860.5 EMT53898.1 - 0.11 13.1 1.3 0.16 12.7 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) Babuvirus_MP PF07234.11 EMT53898.1 - 0.13 12.4 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Movement and RNA silencing protein Response_reg PF00072.24 EMT53899.1 - 3e-27 95.0 0.1 7.7e-27 93.7 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 EMT53899.1 - 3.8e-19 68.0 0.1 6.3e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EMT53899.1 - 5.1e-06 26.1 0.0 1.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT53899.1 - 9e-06 25.1 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Crp PF00325.20 EMT53899.1 - 0.022 14.4 0.3 0.055 13.1 0.3 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_24 PF13412.6 EMT53899.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 EMT53899.1 - 0.11 12.3 0.5 0.44 10.4 0.2 2.0 2 0 0 2 2 2 0 HTH DNA binding domain ZnuA PF01297.17 EMT53900.1 - 2.9e-74 249.7 0.2 3.4e-74 249.5 0.2 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic LPAM_2 PF13627.6 EMT53900.1 - 0.44 10.5 1.5 0.8 9.6 1.5 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site ABC_tran PF00005.27 EMT53901.1 - 3.9e-29 101.9 0.0 6.5e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT53901.1 - 2e-10 41.0 0.1 4.7e-05 23.4 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT53901.1 - 2.5e-07 30.4 1.8 0.0083 15.6 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMT53901.1 - 4.1e-05 24.2 0.5 0.00047 20.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EMT53901.1 - 0.00019 21.6 0.3 0.002 18.3 0.3 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EMT53901.1 - 0.00021 21.0 0.3 0.0006 19.5 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EMT53901.1 - 0.0009 19.8 0.0 0.15 12.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_27 PF13514.6 EMT53901.1 - 0.0036 16.9 0.0 0.0087 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT53901.1 - 0.0067 16.8 1.2 0.039 14.3 1.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EMT53901.1 - 0.0073 16.4 0.0 0.018 15.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EMT53901.1 - 0.0074 16.0 0.2 0.063 13.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EMT53901.1 - 0.013 15.1 0.1 0.65 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EMT53901.1 - 0.024 14.4 0.4 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Spore_IV_A PF09547.10 EMT53901.1 - 0.028 13.4 0.2 0.26 10.2 0.0 2.0 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) AAA PF00004.29 EMT53901.1 - 0.031 14.7 0.7 4.6 7.7 0.1 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EMT53901.1 - 0.033 13.9 0.1 0.07 12.8 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EMT53901.1 - 0.047 13.4 0.6 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EMT53901.1 - 0.057 13.3 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase Mg_chelatase PF01078.21 EMT53901.1 - 0.058 12.8 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MeaB PF03308.16 EMT53901.1 - 0.066 12.2 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EMT53901.1 - 0.069 13.4 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Resolvase PF00239.21 EMT53901.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Resolvase, N terminal domain ATPase_2 PF01637.18 EMT53901.1 - 0.16 11.8 0.2 16 5.3 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ABC-3 PF00950.17 EMT53902.1 - 1.9e-68 230.8 25.2 2.3e-68 230.5 25.2 1.1 1 0 0 1 1 1 1 ABC 3 transport family RIH_assoc PF08454.11 EMT53902.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 RyR and IP3R Homology associated ABC-3 PF00950.17 EMT53903.1 - 1.7e-52 178.5 34.4 5.8e-52 176.8 34.4 1.7 1 1 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 EMT53903.1 - 5.5e-09 35.5 31.9 1.2e-08 34.4 31.9 1.6 1 1 0 1 1 1 1 FecCD transport family DUF1980 PF09323.10 EMT53904.1 - 1.9e-31 109.4 0.0 3.5e-31 108.5 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1980) ArsP_1 PF03773.13 EMT53905.1 - 5.7e-69 232.5 18.7 7.1e-69 232.2 18.7 1.1 1 0 0 1 1 1 1 Predicted permease HTH_5 PF01022.20 EMT53906.1 - 5e-13 48.7 0.0 7.6e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EMT53906.1 - 2.1e-10 40.5 0.0 3.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_34 PF13601.6 EMT53906.1 - 0.024 14.8 0.0 2.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain Pyr_redox_3 PF13738.6 EMT53908.1 - 4.8e-37 127.8 0.0 3.5e-34 118.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMT53908.1 - 4e-14 52.5 0.0 1.3e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMT53908.1 - 3.3e-13 49.5 0.0 2.2e-12 46.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EMT53908.1 - 1.1e-12 47.2 0.0 4.7e-10 38.5 0.0 2.3 1 1 0 2 2 2 2 Flavin-binding monooxygenase-like DAO PF01266.24 EMT53908.1 - 9.5e-10 38.6 2.6 0.0021 17.7 0.2 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMT53908.1 - 3e-09 36.6 0.8 8.4e-06 25.3 0.2 2.9 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 EMT53908.1 - 6.5e-09 35.9 2.1 1.3e-06 28.5 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMT53908.1 - 7.2e-08 31.5 0.6 0.0071 15.1 0.2 2.8 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.6 EMT53908.1 - 8.2e-07 29.1 0.7 0.37 10.8 0.0 4.5 3 1 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EMT53908.1 - 1.1e-06 28.0 0.7 0.0022 17.2 0.3 3.1 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 EMT53908.1 - 2.8e-06 26.7 0.3 0.026 13.6 0.0 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.17 EMT53908.1 - 2.8e-05 23.5 0.7 0.001 18.3 0.1 2.5 2 1 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EMT53908.1 - 0.00013 22.5 0.0 2.3 8.8 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMT53908.1 - 0.0019 17.3 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein ApbA PF02558.16 EMT53908.1 - 0.016 14.9 0.4 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EMT53908.1 - 0.017 15.0 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 EMT53908.1 - 0.018 14.4 0.0 0.12 11.6 0.0 1.9 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 EMT53908.1 - 0.021 14.9 0.3 6.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EMT53908.1 - 0.023 15.0 0.3 2 8.7 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain DUF4147 PF13660.6 EMT53908.1 - 0.07 12.7 0.0 8.6 5.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Cation_efflux PF01545.21 EMT53909.1 - 9.1e-50 169.2 19.1 1.1e-49 168.8 19.1 1.1 1 0 0 1 1 1 1 Cation efflux family TctB PF07331.11 EMT53909.1 - 2.4 8.4 17.6 37 4.6 15.2 2.4 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family AMP-binding PF00501.28 EMT53910.1 - 1.8e-94 316.7 0.0 2.4e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMT53910.1 - 1.6e-25 89.8 0.6 5.4e-25 88.2 0.4 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EMT53910.1 - 1.9 8.5 6.1 0.14 12.1 0.4 2.1 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus Metallophos PF00149.28 EMT53911.1 - 2.2e-09 38.1 0.1 5.5e-09 36.8 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMT53911.1 - 2.2e-08 34.5 0.2 4.7e-08 33.4 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HTH_30 PF13556.6 EMT53912.1 - 1.2e-18 66.7 2.9 2.6e-18 65.6 2.6 1.7 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_8 PF02954.19 EMT53912.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family DUF2089 PF09862.9 EMT53912.1 - 0.032 14.3 0.1 0.056 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_28 PF13518.6 EMT53912.1 - 0.1 12.7 0.0 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain ABC_tran PF00005.27 EMT53913.1 - 1.9e-29 102.9 0.0 1.7e-28 99.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter OB_MalK PF17912.1 EMT53913.1 - 2.6e-16 60.2 0.0 7.8e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 MalK OB fold domain AAA_21 PF13304.6 EMT53913.1 - 9.3e-09 35.5 0.1 0.0016 18.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 EMT53913.1 - 8e-07 29.1 0.0 2.9e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 TOBE domain SMC_N PF02463.19 EMT53913.1 - 4.1e-05 23.1 0.2 0.00035 20.1 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EMT53913.1 - 4.8e-05 23.4 0.0 7.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain CysA_C_terminal PF17850.1 EMT53913.1 - 6.7e-05 23.4 0.0 0.00015 22.2 0.0 1.7 1 0 0 1 1 1 1 CysA C-terminal regulatory domain AAA_22 PF13401.6 EMT53913.1 - 0.00032 21.0 0.0 0.00062 20.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMT53913.1 - 0.004 16.9 0.0 0.025 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMT53913.1 - 0.0055 16.6 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase ATPase_2 PF01637.18 EMT53913.1 - 0.0081 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EMT53913.1 - 0.01 16.2 0.1 0.017 15.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EMT53913.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMT53913.1 - 0.022 15.3 0.0 0.045 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMT53913.1 - 0.025 14.7 0.2 0.4 10.8 0.3 2.7 2 2 0 2 2 2 0 AAA domain TOBE PF03459.17 EMT53913.1 - 0.026 14.8 0.0 0.083 13.2 0.0 1.9 1 0 0 1 1 1 0 TOBE domain AAA_29 PF13555.6 EMT53913.1 - 0.038 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EMT53913.1 - 0.042 14.3 0.0 0.095 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EMT53913.1 - 0.066 13.6 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EMT53913.1 - 0.14 11.9 0.1 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMT53913.1 - 0.14 12.6 0.0 0.55 10.6 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Hydrolase_3 PF08282.12 EMT53914.1 - 1.7e-59 201.7 0.0 1.9e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EMT53914.1 - 1.7e-12 47.4 0.0 8.4e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EMT53914.1 - 1.7e-12 48.1 1.6 0.00083 19.7 0.0 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMT53914.1 - 9.1e-10 39.2 5.3 0.00024 21.5 0.0 3.4 2 2 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMT53914.1 - 6.1e-06 26.4 0.3 2 8.5 0.4 3.2 2 1 1 3 3 3 3 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EMT53914.1 - 0.00012 22.1 0.0 0.00036 20.6 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 EMT53914.1 - 0.026 13.6 0.0 3.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Trehalose-phosphatase Acid_phosphat_B PF03767.14 EMT53914.1 - 0.1 12.2 0.1 4.4 6.8 0.2 2.2 1 1 1 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Peptidase_S8 PF00082.22 EMT53915.1 - 8.2e-48 163.2 3.5 1.1e-47 162.8 3.5 1.1 1 0 0 1 1 1 1 Subtilase family Lipase_GDSL_2 PF13472.6 EMT53915.1 - 0.053 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Speriolin_C PF15059.6 EMT53915.1 - 0.054 13.6 0.0 7.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Speriolin C-terminus SCAB-PH PF17684.1 EMT53915.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein Flavodoxin_2 PF02525.17 EMT53916.1 - 1e-42 146.1 0.1 1.2e-42 145.9 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EMT53916.1 - 1.8e-13 50.5 0.0 2.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 EMT53916.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.6 2 0 0 2 2 2 0 Flavodoxin DUF3907 PF13047.6 EMT53917.1 - 3.8e-57 192.4 6.8 4.3e-57 192.2 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3907) HTH_51 PF18558.1 EMT53917.1 - 0.016 15.0 0.1 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain ABC2_membrane_3 PF12698.7 EMT53918.1 - 1.8e-35 122.7 14.5 2.3e-35 122.3 14.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 EMT53918.1 - 7.5e-17 61.4 26.1 1.3e-15 57.4 14.4 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 EMT53918.1 - 4.1e-07 29.6 11.6 6.2e-07 29.0 11.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein SQHop_cyclase_C PF13243.6 EMT53918.1 - 0.0016 17.6 0.1 0.0025 17.0 0.1 1.2 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain Phage_Coat_Gp8 PF05371.12 EMT53918.1 - 0.76 9.6 3.6 8.7 6.2 0.0 3.0 3 0 0 3 3 3 0 Phage major coat protein, Gp8 DUF4017 PF13209.6 EMT53918.1 - 0.98 9.4 6.7 1.1 9.2 1.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4017) HlyD_3 PF13437.6 EMT53919.1 - 7.5e-15 55.5 8.1 8.9e-14 52.1 0.6 2.8 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 EMT53919.1 - 2.3e-12 46.6 26.0 1.1e-08 34.5 9.3 2.7 1 1 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 EMT53919.1 - 5.5e-11 42.1 4.3 8.5e-09 35.1 0.3 4.8 4 2 0 4 4 4 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 EMT53919.1 - 1.1e-09 38.0 2.8 0.0026 17.6 0.3 3.7 3 0 0 3 3 3 2 Biotin-requiring enzyme Peptidase_M23 PF01551.22 EMT53919.1 - 9.4e-05 22.6 3.4 0.088 13.0 0.2 2.7 2 0 0 2 2 2 2 Peptidase family M23 PTS_EIIA_1 PF00358.20 EMT53919.1 - 0.0013 18.4 0.2 0.075 12.8 0.1 2.7 2 0 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 EMT53919.1 - 0.016 15.1 3.1 0.069 13.1 0.1 2.8 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain OEP PF02321.18 EMT53919.1 - 0.019 14.8 42.4 0.32 10.8 19.6 3.5 1 1 3 4 4 4 0 Outer membrane efflux protein ATP-synt_ab_Xtn PF16886.5 EMT53919.1 - 0.17 11.8 3.2 4.9 7.1 0.1 3.3 3 1 0 3 3 3 0 ATPsynthase alpha/beta subunit N-term extension HlyD_2 PF12700.7 EMT53919.1 - 0.2 10.4 10.0 0.24 10.1 0.1 2.3 2 0 0 2 2 2 0 HlyD family secretion protein Peptidase_M32 PF02074.15 EMT53919.1 - 1.4 7.6 11.4 2 7.1 11.4 1.2 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase TetR_N PF00440.23 EMT53920.1 - 1.2e-17 63.4 1.2 2.3e-17 62.5 1.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_4 PF08359.11 EMT53920.1 - 3e-05 24.2 0.1 4.6e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 YsiA-like protein, C-terminal region Amidohydro_1 PF01979.20 EMT53920.1 - 0.054 12.8 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family TetR_C_21 PF17926.1 EMT53920.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain BTAD PF03704.17 EMT53921.1 - 2.6e-25 89.5 0.6 2.6e-25 89.5 0.6 4.3 6 0 0 6 6 4 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 EMT53921.1 - 2e-07 31.2 39.6 0.0041 17.4 1.6 9.9 8 3 2 10 10 10 4 Tetratricopeptide repeat NACHT PF05729.12 EMT53921.1 - 5e-06 26.5 0.0 2.1e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EMT53921.1 - 1.5e-05 25.5 0.4 0.00015 22.2 0.0 3.0 3 1 0 3 3 2 1 AAA ATPase domain TPR_10 PF13374.6 EMT53921.1 - 2.7e-05 23.9 8.1 2.3 8.2 0.4 6.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EMT53921.1 - 5.2e-05 22.8 3.9 5.2e-05 22.8 3.9 3.6 2 1 2 4 4 4 2 MalT-like TPR region ANAPC3 PF12895.7 EMT53921.1 - 6.4e-05 23.1 4.3 0.46 10.7 0.2 4.7 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EMT53921.1 - 7.3e-05 22.7 8.0 1.1 9.6 0.0 6.5 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMT53921.1 - 0.00054 20.6 31.9 0.8 10.7 0.5 9.4 6 3 4 10 10 9 2 Tetratricopeptide repeat Trans_reg_C PF00486.28 EMT53921.1 - 0.0012 18.9 1.1 0.0058 16.7 0.1 2.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal AAA_22 PF13401.6 EMT53921.1 - 0.0039 17.5 0.0 0.013 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.28 EMT53921.1 - 0.0061 16.3 11.6 1.3 8.9 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMT53921.1 - 0.011 16.0 3.6 4.5 7.9 0.0 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EMT53921.1 - 0.022 15.3 24.0 0.35 11.4 0.6 7.0 5 3 3 8 8 8 0 Tetratricopeptide repeat 5-nucleotidase PF06189.12 EMT53921.1 - 0.094 11.6 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase TPR_2 PF07719.17 EMT53921.1 - 0.1 12.8 35.1 0.66 10.2 0.1 9.9 10 1 0 11 11 10 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMT53921.1 - 0.23 12.2 0.1 0.23 12.2 0.1 6.6 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EMT53921.1 - 0.24 11.5 21.3 0.2 11.8 0.6 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat NB-ARC PF00931.22 EMT53921.1 - 1.1 8.4 4.5 10 5.2 1.3 3.3 2 1 0 2 2 2 0 NB-ARC domain TPR_16 PF13432.6 EMT53921.1 - 4.8 7.9 29.8 0.16 12.7 1.2 7.4 8 1 0 9 9 7 0 Tetratricopeptide repeat Spore_YhcN_YlaJ PF09580.10 EMT53922.1 - 1.8e-08 34.6 0.4 5.5e-08 33.1 0.4 1.7 1 1 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Cu_amine_oxidN1 PF07833.11 EMT53923.1 - 8.5e-28 96.7 0.0 1.6e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase N-terminal domain P22_AR_N PF10547.9 EMT53923.1 - 0.0053 17.1 0.0 0.12 12.7 0.0 2.1 1 1 1 2 2 2 1 P22_AR N-terminal domain DUF1343 PF07075.11 EMT53924.1 - 5.4e-108 361.5 0.0 8e-108 360.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) Polysacc_deac_1 PF01522.21 EMT53924.1 - 4.3e-31 107.4 0.1 5e-30 104.0 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 EMT53924.1 - 0.0023 17.6 1.0 0.0078 15.9 1.0 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Flg_new PF09479.10 EMT53924.1 - 0.038 14.2 0.8 0.13 12.5 0.8 1.9 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) zf-Di19 PF05605.12 EMT53925.1 - 0.0087 16.3 0.4 0.0096 16.2 0.4 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Herpes_UL52 PF03121.15 EMT53925.1 - 0.049 13.6 0.6 0.056 13.4 0.6 1.0 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase Hemocyanin_N PF03722.14 EMT53925.1 - 0.16 12.5 0.0 0.18 12.3 0.0 1.0 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain AMP-binding PF00501.28 EMT53926.1 - 1.3e-103 346.8 0.0 1.6e-103 346.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMT53926.1 - 3.8e-21 75.9 0.7 7.9e-21 74.8 0.7 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3817 PF12823.7 EMT53927.1 - 8.9e-22 77.7 4.0 1e-21 77.5 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3817) ABC2_membrane_2 PF12679.7 EMT53927.1 - 0.1 11.8 2.6 0.11 11.7 2.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Aldedh PF00171.22 EMT53928.1 - 2.9e-161 537.1 0.7 3.3e-161 536.9 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SbsC_C PF18058.1 EMT53928.1 - 0.41 10.9 1.6 0.73 10.1 1.6 1.3 1 0 0 1 1 1 0 SbsC C-terminal domain Aminotran_3 PF00202.21 EMT53929.1 - 2.2e-131 438.3 0.0 2.6e-131 438.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMT53929.1 - 0.035 13.3 0.0 0.46 9.6 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II Peptidase_M20 PF01546.28 EMT53930.1 - 3.6e-39 134.6 0.1 4.6e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT53930.1 - 5.9e-17 61.6 0.0 1.2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT53930.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 CoA_trans PF01144.23 EMT53931.1 - 9.3e-35 120.0 0.4 1.1e-34 119.7 0.4 1.0 1 0 0 1 1 1 1 Coenzyme A transferase DeoRC PF00455.22 EMT53931.1 - 0.001 19.0 0.1 0.043 13.7 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain CoA_trans PF01144.23 EMT53932.1 - 2.2e-67 226.7 3.3 2.4e-67 226.5 3.3 1.0 1 0 0 1 1 1 1 Coenzyme A transferase Mal_decarbox_Al PF16957.5 EMT53932.1 - 0.003 16.0 0.2 0.0041 15.5 0.2 1.1 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter Aminotran_3 PF00202.21 EMT53933.1 - 1.1e-103 347.0 0.0 1.4e-103 346.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EMT53933.1 - 0.021 14.1 0.0 0.045 13.0 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase PucR PF07905.11 EMT53934.1 - 1e-31 109.6 0.0 2.2e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 EMT53934.1 - 1.7e-21 75.7 2.4 4.2e-21 74.5 2.4 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 EMT53934.1 - 1e-15 58.0 0.4 2.6e-15 56.7 0.4 1.7 1 0 0 1 1 1 1 GGDEF-like domain Acetyltransf_9 PF13527.7 EMT53935.1 - 8e-10 38.9 0.0 4.4e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT53935.1 - 3.3e-05 23.8 0.0 0.0055 16.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT53935.1 - 0.00011 22.4 0.0 0.00055 20.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT53935.1 - 0.00035 20.8 0.0 0.00061 20.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT53935.1 - 0.037 14.4 0.0 0.089 13.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GDPD PF03009.17 EMT53936.1 - 1.1e-45 156.5 0.1 2.5e-45 155.3 0.1 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EMT53936.1 - 0.0011 19.4 0.3 0.0037 17.7 0.2 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family TMP-TENI PF02581.17 EMT53936.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase PI-PLC-X PF00388.19 EMT53936.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Radical_SAM_C PF16199.5 EMT53937.1 - 7.7e-25 86.7 0.1 1.5e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EMT53937.1 - 3.5e-20 73.0 0.2 5.9e-20 72.3 0.2 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DEADboxA PF12343.8 EMT53937.1 - 0.15 12.6 0.9 0.26 11.9 0.9 1.3 1 0 0 1 1 1 0 Cold shock protein DEAD box A Glyco_tranf_2_3 PF13641.6 EMT53938.1 - 1.5e-30 106.8 0.0 1.9e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EMT53938.1 - 7.1e-17 62.0 9.5 1.9e-16 60.6 9.5 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EMT53938.1 - 6.7e-11 42.3 0.0 1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EMT53938.1 - 6.9e-08 32.2 0.7 2.4e-07 30.4 0.1 2.0 2 1 1 3 3 3 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 EMT53938.1 - 7e-08 32.9 0.1 1.5e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.14 EMT53938.1 - 0.039 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Anp1 DUF4179 PF13786.6 EMT53939.1 - 0.1 13.1 0.3 0.6 10.6 0.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Transposase_mut PF00872.18 EMT53941.1 - 6.5e-27 94.4 0.1 7.9e-27 94.1 0.1 1.0 1 0 0 1 1 1 1 Transposase, Mutator family IL10 PF00726.17 EMT53941.1 - 0.12 11.8 0.0 0.23 11.0 0.0 1.5 1 1 0 1 1 1 0 Interleukin 10 AHSA1 PF08327.11 EMT53942.1 - 8.4e-25 87.4 0.3 9.9e-25 87.2 0.3 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EMT53942.1 - 0.0031 17.8 0.3 0.0036 17.6 0.3 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport B3_4 PF03483.17 EMT53943.1 - 6.5e-25 87.8 0.0 8.8e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 B3/4 domain LysE PF01810.18 EMT53944.1 - 2e-32 112.2 10.7 2.7e-32 111.8 10.7 1.2 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 EMT53944.1 - 0.021 14.5 5.9 0.02 14.6 4.1 2.1 1 1 0 1 1 1 0 Integral membrane protein TerC family FMN_bind_2 PF04299.12 EMT53945.1 - 5.1e-50 169.5 0.4 6.9e-50 169.0 0.4 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain Pyridox_ox_2 PF12900.7 EMT53945.1 - 0.064 13.3 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 EMT53946.1 - 1.2e-45 155.2 0.1 1.8e-45 154.7 0.1 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain Aminotran_1_2 PF00155.21 EMT53947.1 - 1.6e-24 86.8 0.0 2.1e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EMT53947.1 - 2.2e-13 49.6 0.0 4.1e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EMT53947.1 - 0.0075 15.8 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EMT53947.1 - 0.087 12.8 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 EMT53947.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 EMT53947.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_11 PF08279.12 EMT53947.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 HTH domain EamA PF00892.20 EMT53948.1 - 2.4e-48 163.8 42.0 1.3e-25 90.2 18.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EMT53948.1 - 1.5e-05 24.5 11.8 1.5e-05 24.5 11.8 1.9 1 1 0 2 2 2 1 Triose-phosphate Transporter family PUNUT PF16913.5 EMT53948.1 - 0.0013 18.0 10.6 0.0013 18.0 10.6 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Pyrophosphatase PF00719.19 EMT53950.1 - 3.8e-07 30.1 0.0 4.4e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase InPase PF18823.1 EMT53950.1 - 0.056 13.1 0.1 0.068 12.9 0.1 1.3 1 0 0 1 1 1 0 Inorganic Pyrophosphatase H_kinase_N PF12282.8 EMT53950.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Signal transduction histidine kinase ABC_tran PF00005.27 EMT53951.1 - 1.9e-29 102.9 0.0 2.9e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EMT53951.1 - 1.4e-18 67.6 0.1 1.9e-18 67.1 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EMT53951.1 - 1.9e-09 37.3 0.0 9.5e-09 35.0 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT53951.1 - 2.4e-06 27.6 0.0 0.00026 20.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMT53951.1 - 0.00024 21.4 0.7 0.0019 18.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EMT53951.1 - 0.00029 20.6 0.1 0.00049 19.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT53951.1 - 0.00047 20.6 0.3 0.00047 20.6 0.3 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EMT53951.1 - 0.00069 20.1 0.0 0.005 17.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EMT53951.1 - 0.0021 17.9 0.0 0.63 9.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMT53951.1 - 0.0023 17.7 3.5 0.0023 17.7 0.5 2.5 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EMT53951.1 - 0.0087 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EMT53951.1 - 0.012 15.3 0.8 0.023 14.4 0.1 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EMT53951.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 EMT53951.1 - 0.025 14.6 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EMT53951.1 - 0.031 14.2 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 EMT53951.1 - 0.032 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 EMT53951.1 - 0.035 14.4 0.4 0.6 10.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EMT53951.1 - 0.039 14.5 0.0 0.062 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EMT53951.1 - 0.041 13.8 0.0 0.85 9.5 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.6 EMT53951.1 - 0.074 13.6 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EMT53951.1 - 0.076 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PRK PF00485.18 EMT53951.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EMT53951.1 - 0.09 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EMT53951.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 EMT53951.1 - 0.1 12.8 0.4 1.4 9.2 0.4 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EMT53952.1 - 3.2e-29 102.2 0.0 5.3e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EMT53952.1 - 3.6e-27 95.7 4.1 5.3e-27 95.2 4.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EMT53952.1 - 1.2e-08 34.6 0.0 3.5e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EMT53952.1 - 0.00037 20.3 0.0 0.00086 19.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 EMT53952.1 - 0.0011 17.9 0.0 0.032 13.0 0.0 2.4 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 EMT53952.1 - 0.0014 19.1 0.4 0.0057 17.1 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EMT53952.1 - 0.0023 17.8 0.1 0.063 13.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMT53952.1 - 0.0025 18.1 0.0 0.021 15.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMT53952.1 - 0.0033 17.0 0.6 0.21 11.2 0.0 2.9 2 1 1 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EMT53952.1 - 0.0038 17.2 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 EMT53952.1 - 0.0099 16.1 0.9 0.39 11.0 0.9 2.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EMT53952.1 - 0.017 15.6 0.0 0.026 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMT53952.1 - 0.051 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EMT53952.1 - 0.056 13.2 3.6 0.092 12.4 0.4 3.0 2 1 0 2 2 2 0 AAA domain DUF3584 PF12128.8 EMT53952.1 - 0.082 10.4 0.1 0.12 9.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Zeta_toxin PF06414.12 EMT53952.1 - 0.083 12.2 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EMT53952.1 - 0.12 12.9 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Spo7_2_N PF15407.6 EMT53952.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 SBP_bac_5 PF00496.22 EMT53953.1 - 5.5e-75 252.7 0.1 7e-75 252.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle ABC_tran PF00005.27 EMT53954.1 - 2.5e-27 96.0 0.0 3.3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EMT53954.1 - 9.5e-06 25.9 0.0 3.2e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT53954.1 - 0.00042 20.0 0.1 0.001 18.8 0.0 1.7 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT53954.1 - 0.0012 19.2 0.1 0.0017 18.8 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EMT53954.1 - 0.0028 17.8 0.0 0.0074 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EMT53954.1 - 0.0031 17.0 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT53954.1 - 0.0052 16.6 0.1 1.7 8.4 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EMT53954.1 - 0.0091 15.3 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.26 EMT53954.1 - 0.011 15.4 0.0 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 EMT53954.1 - 0.012 16.2 0.0 0.026 15.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EMT53954.1 - 0.013 15.4 0.1 0.031 14.2 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 EMT53954.1 - 0.029 14.6 0.0 0.13 12.5 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 EMT53954.1 - 0.033 13.6 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 EMT53954.1 - 0.04 13.1 0.0 0.042 13.0 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit PolyG_pol PF01518.16 EMT53954.1 - 0.046 12.4 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Sigma NS protein AAA_24 PF13479.6 EMT53954.1 - 0.046 13.4 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EMT53954.1 - 0.05 13.7 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain TniB PF05621.11 EMT53954.1 - 0.072 12.5 0.0 1.4 8.3 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 EMT53954.1 - 0.092 12.7 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EMT53954.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Tub_N PF16322.5 EMT53954.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Tubby N-terminal ABC_tran PF00005.27 EMT53955.1 - 4.4e-23 82.3 0.0 6.3e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EMT53955.1 - 3.8e-05 24.0 0.9 0.00032 21.0 0.9 2.3 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EMT53955.1 - 4.2e-05 23.5 0.0 0.0061 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT53955.1 - 0.00014 21.4 0.0 0.00023 20.7 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMT53955.1 - 0.0013 19.1 0.6 0.0027 18.1 0.6 1.6 1 1 0 1 1 1 1 AAA ATPase domain oligo_HPY PF08352.12 EMT53955.1 - 0.0029 18.1 0.1 0.0087 16.6 0.0 1.8 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region AAA PF00004.29 EMT53955.1 - 0.0032 17.9 0.0 0.011 16.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMT53955.1 - 0.0085 16.1 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EMT53955.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EMT53955.1 - 0.022 14.6 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 EMT53955.1 - 0.03 13.7 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EMT53955.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2791 PF10923.8 EMT53955.1 - 0.062 12.1 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_30 PF13604.6 EMT53955.1 - 0.081 12.6 0.3 0.16 11.7 0.3 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 EMT53955.1 - 0.09 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 EMT53955.1 - 0.1 12.7 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain BPD_transp_1 PF00528.22 EMT53956.1 - 1.5e-22 80.2 8.6 1.5e-22 80.2 8.6 1.8 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT53956.1 - 1.8e-05 24.6 1.9 1.8e-05 24.6 1.9 2.8 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C Cytochrom_B559 PF00283.19 EMT53956.1 - 0.21 11.1 1.2 0.45 10.0 1.2 1.5 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits DUF2627 PF11118.8 EMT53956.1 - 4.1 8.1 6.9 1.7 9.3 2.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) BPD_transp_1 PF00528.22 EMT53957.1 - 1.1e-38 132.8 14.3 1.6e-38 132.3 14.3 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component MarR PF01047.22 EMT53958.1 - 6.4e-12 45.2 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EMT53958.1 - 3.1e-08 33.1 0.2 5.2e-08 32.3 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EMT53958.1 - 9.7e-08 31.8 0.0 2.1e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 MarR family HTH_27 PF13463.6 EMT53958.1 - 1e-07 32.3 0.1 2.6e-07 31.0 0.0 1.7 2 0 0 2 2 1 1 Winged helix DNA-binding domain HTH_34 PF13601.6 EMT53958.1 - 0.00014 22.0 0.2 0.00034 20.7 0.1 1.8 2 1 0 2 2 1 1 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 EMT53958.1 - 0.00016 21.8 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain RPA_C PF08784.11 EMT53958.1 - 0.00073 20.2 0.0 0.0011 19.5 0.0 1.3 1 0 0 1 1 1 1 Replication protein A C terminal HTH_Crp_2 PF13545.6 EMT53958.1 - 0.00082 19.3 0.1 0.0026 17.7 0.0 1.7 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 EMT53958.1 - 0.00095 19.5 0.1 0.0022 18.3 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 EMT53958.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DprA_WH PF17782.1 EMT53958.1 - 0.0031 17.6 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 DprA winged helix domain HTH_IclR PF09339.10 EMT53958.1 - 0.0045 16.8 0.1 0.01 15.6 0.0 1.6 2 0 0 2 2 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 EMT53958.1 - 0.0049 16.7 0.1 0.013 15.3 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family BLACT_WH PF17778.1 EMT53958.1 - 0.012 15.6 0.4 0.053 13.5 0.1 2.1 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain PadR PF03551.14 EMT53958.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 EMT53958.1 - 0.025 14.6 0.0 0.062 13.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S25 PF03297.15 EMT53958.1 - 0.029 14.6 0.1 0.029 14.6 0.1 1.7 2 0 0 2 2 1 0 S25 ribosomal protein YdaS_antitoxin PF15943.5 EMT53958.1 - 0.041 13.8 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT SMC_ScpB PF04079.16 EMT53958.1 - 0.041 13.5 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB DUF4423 PF14394.6 EMT53958.1 - 0.044 13.5 0.2 0.064 13.0 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_11 PF08279.12 EMT53958.1 - 0.044 13.7 0.1 0.081 12.9 0.1 1.4 1 0 0 1 1 1 0 HTH domain FeoC PF09012.10 EMT53958.1 - 0.047 13.8 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator Sigma70_r4 PF04545.16 EMT53958.1 - 0.048 13.2 0.1 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_3 PF01381.22 EMT53958.1 - 0.079 13.0 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix Crp PF00325.20 EMT53958.1 - 0.1 12.3 0.3 0.19 11.4 0.3 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_1 PF00126.27 EMT53958.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.6 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family MerR PF00376.23 EMT53958.1 - 0.19 11.5 0.1 1.2 8.9 0.1 2.2 1 1 0 1 1 1 0 MerR family regulatory protein Thioredoxin_9 PF14595.6 EMT53960.1 - 4.9e-40 136.3 0.0 6.8e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin RinB PF06116.12 EMT53960.1 - 0.036 14.2 0.1 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 Transcriptional activator RinB YycC PF14174.6 EMT53961.1 - 4.8e-27 93.5 7.2 5.2e-27 93.4 7.2 1.0 1 0 0 1 1 1 1 YycC-like protein HTH_3 PF01381.22 EMT53961.1 - 0.0044 17.0 0.1 0.0081 16.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix 2-ph_phosp PF04029.14 EMT53962.1 - 4.3e-25 88.2 0.0 5.4e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 2-phosphosulpholactate phosphatase PGA_cap PF09587.10 EMT53964.1 - 4e-78 262.4 0.0 5.5e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap TetR_C_32 PF09209.11 EMT53964.1 - 0.026 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sigma_reg_N PF13800.6 EMT53964.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3328 PF11807.8 EMT53964.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) AhpC-TSA PF00578.21 EMT53965.1 - 5e-25 87.8 0.0 6e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMT53965.1 - 9.3e-21 74.1 0.0 1.1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 EMT53965.1 - 1e-16 60.8 0.0 1.9e-13 50.3 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 EMT53965.1 - 9.8e-12 45.1 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EMT53965.1 - 6.7e-10 39.4 0.0 9.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain T4_deiodinase PF00837.17 EMT53965.1 - 0.00017 21.0 0.0 0.00032 20.1 0.0 1.4 1 1 1 2 2 2 1 Iodothyronine deiodinase Thioredoxin_7 PF13899.6 EMT53965.1 - 0.0008 19.5 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 EMT53965.1 - 0.022 14.6 0.0 0.17 11.6 0.0 2.0 1 1 0 1 1 1 0 F plasmid transfer operon protein SHS2_FTSA PF02491.20 EMT53965.1 - 0.075 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA DsbD PF02683.15 EMT53966.1 - 1.7e-54 184.9 16.0 2e-54 184.7 16.0 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 EMT53966.1 - 3.3e-07 30.5 18.8 5.7e-07 29.7 18.7 1.5 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF5366 PF17328.2 EMT53966.1 - 0.038 14.1 0.3 0.038 14.1 0.3 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5366) RseC_MucC PF04246.12 EMT53966.1 - 0.075 13.0 8.4 0.16 11.9 1.3 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC TMEM100 PF16311.5 EMT53966.1 - 0.13 11.8 3.1 0.084 12.5 1.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 100 COX7C PF02935.16 EMT53966.1 - 0.49 10.7 8.0 3.2 8.1 0.6 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc HisKA PF00512.25 EMT53967.1 - 1e-16 60.7 1.7 1.7e-16 60.0 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 EMT53967.1 - 1.1e-16 61.4 0.0 2.4e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 EMT53967.1 - 8.7e-08 32.4 0.1 2.6e-07 30.8 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EMT53967.1 - 9.1e-07 28.9 0.9 4.5e-06 26.6 0.3 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EMT53967.1 - 3.1e-05 24.2 0.0 9.8e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 EMT53967.1 - 8.8e-05 22.3 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EMT53967.1 - 0.00098 19.0 0.0 0.0028 17.5 0.0 1.7 1 0 0 1 1 1 1 GHKL domain PAS_10 PF13596.6 EMT53967.1 - 0.012 16.2 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 EMT53967.1 - 0.04 14.0 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 PAS domain GAF PF01590.26 EMT53967.1 - 0.061 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 GAF domain Biopterin_H PF00351.21 EMT53968.1 - 4.4e-29 101.6 0.0 1.4e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 Biopterin-dependent aromatic amino acid hydroxylase MIX PF18529.1 EMT53968.1 - 0.0054 16.4 0.2 0.017 14.8 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial membrane-anchored proteins ABM PF03992.16 EMT53969.1 - 5.6e-18 64.8 0.0 6.5e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase TMP-TENI PF02581.17 EMT53971.1 - 3.3e-60 202.5 2.8 3.9e-60 202.3 2.8 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase NMO PF03060.15 EMT53971.1 - 0.00011 21.7 6.5 0.00014 21.4 6.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DUF561 PF04481.12 EMT53971.1 - 0.0031 16.7 1.5 0.14 11.3 0.2 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF561) QRPTase_C PF01729.19 EMT53971.1 - 0.0092 15.8 0.0 0.025 14.3 0.0 1.7 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain DHO_dh PF01180.21 EMT53971.1 - 0.046 12.9 3.2 0.029 13.6 1.6 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.14 EMT53971.1 - 0.38 10.0 8.4 0.13 11.5 4.8 1.9 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 EMT53972.1 - 7.2e-47 159.1 0.2 8.5e-47 158.8 0.2 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase ThiG PF05690.14 EMT53972.1 - 0.00035 20.0 1.1 0.00089 18.6 0.6 2.0 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 EMT53972.1 - 0.0097 15.3 1.4 0.015 14.7 1.4 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase QRPTase_C PF01729.19 EMT53972.1 - 0.081 12.7 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF5616 PF18481.1 EMT53973.1 - 0.029 14.7 0.0 0.034 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5616) Vir_act_alpha_C PF10400.9 EMT53973.1 - 0.063 14.0 0.2 0.091 13.5 0.2 1.2 1 0 0 1 1 1 0 Virulence activator alpha C-term DUF3054 PF11255.8 EMT53974.1 - 7.9e-22 77.9 8.9 9.9e-22 77.5 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3054) DUF4870 PF09685.10 EMT53974.1 - 0.1 12.7 9.8 0.16 12.0 9.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4870) Chromate_transp PF02417.15 EMT53974.1 - 0.14 12.3 10.9 0.18 11.9 10.9 1.1 1 0 0 1 1 1 0 Chromate transporter E1-E2_ATPase PF00122.20 EMT53974.1 - 0.42 10.1 4.7 0.086 12.4 0.6 1.8 1 1 1 2 2 2 0 E1-E2 ATPase FA_desaturase PF00487.24 EMT53974.1 - 1.5 8.6 13.4 2 8.2 13.4 1.3 1 1 0 1 1 1 0 Fatty acid desaturase DUF2070 PF09843.9 EMT53974.1 - 7.4 4.7 7.4 8.4 4.6 7.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Acetyltransf_3 PF13302.7 EMT53975.1 - 9.4e-20 71.7 0.0 1.1e-19 71.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT53975.1 - 0.00017 21.8 0.0 0.00024 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 EMT53975.1 - 0.059 13.5 0.0 0.087 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMT53975.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UbiD PF01977.16 EMT53976.1 - 7.1e-140 466.4 1.2 5.6e-136 453.6 0.1 2.0 2 0 0 2 2 2 2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Transp_cyt_pur PF02133.15 EMT53977.1 - 5.5e-106 355.0 44.6 6.8e-106 354.7 44.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3951 PF13131.6 EMT53977.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3951) MCPsignal PF00015.21 EMT53978.1 - 3.6e-52 176.6 31.4 3.6e-52 176.6 31.4 4.0 2 2 2 4 4 4 3 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 EMT53978.1 - 4.8e-38 130.5 8.1 4.8e-38 130.5 8.1 3.5 4 1 0 4 4 4 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 EMT53978.1 - 3e-10 40.3 0.1 3e-10 40.3 0.1 4.7 4 2 0 4 4 4 1 HAMP domain TarH PF02203.15 EMT53978.1 - 3.2e-08 33.7 4.1 3.2e-08 33.7 4.1 4.8 4 1 0 4 4 4 1 Tar ligand binding domain homologue FadA PF09403.10 EMT53978.1 - 0.0093 16.4 3.0 0.0093 16.4 3.0 4.7 3 2 2 5 5 5 1 Adhesion protein FadA DUF4441 PF14536.6 EMT53978.1 - 0.37 11.0 2.0 1.8 8.8 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) DUF948 PF06103.11 EMT53978.1 - 0.97 9.7 37.5 0.46 10.8 3.8 6.6 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) TMP_2 PF06791.13 EMT53978.1 - 1 9.0 37.2 0.051 13.2 12.8 3.8 1 1 2 3 3 3 0 Prophage tail length tape measure protein DASH_Dad1 PF08649.10 EMT53978.1 - 6.2 7.1 14.0 4.8 7.5 0.3 5.3 5 1 0 5 5 5 0 DASH complex subunit Dad1 CN_hydrolase PF00795.22 EMT53980.1 - 2.6e-58 197.4 0.0 2.9e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Amidohydro_1 PF01979.20 EMT53981.1 - 5.8e-29 101.5 0.0 1.3e-28 100.3 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMT53981.1 - 1.8e-16 60.7 1.9 2e-06 27.6 0.0 3.3 2 1 0 3 3 3 3 Amidohydrolase family TatD_DNase PF01026.21 EMT53981.1 - 0.00016 21.1 0.1 0.00027 20.4 0.1 1.3 1 0 0 1 1 1 1 TatD related DNase DHO_dh PF01180.21 EMT53982.1 - 1.4e-32 113.2 0.0 2e-32 112.6 0.0 1.3 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_21 PF14697.6 EMT53982.1 - 2.4e-23 82.0 15.3 4.2e-23 81.2 15.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Dus PF01207.17 EMT53982.1 - 2.7e-11 43.1 0.3 9.1e-10 38.1 0.0 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Fer4 PF00037.27 EMT53982.1 - 4.9e-07 29.3 15.9 0.0002 21.0 4.7 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EMT53982.1 - 4.1e-06 27.3 13.0 9.3e-06 26.1 13.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMT53982.1 - 9.7e-06 25.6 9.8 0.0042 17.2 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EMT53982.1 - 0.00062 19.7 20.0 0.012 15.7 2.5 2.7 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EMT53982.1 - 0.0011 18.9 13.4 0.045 13.9 2.7 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EMT53982.1 - 0.0012 18.9 12.7 0.0081 16.3 13.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EMT53982.1 - 0.0017 18.8 5.9 0.33 11.5 0.7 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EMT53982.1 - 0.0026 18.1 13.4 0.4 11.3 5.0 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain MtrH PF02007.18 EMT53982.1 - 0.0034 16.5 0.1 0.014 14.5 0.0 1.9 2 0 0 2 2 2 1 Tetrahydromethanopterin S-methyltransferase MtrH subunit NMO PF03060.15 EMT53982.1 - 0.0091 15.4 1.4 0.042 13.2 1.4 2.0 1 1 1 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.18 EMT53982.1 - 0.017 14.2 1.6 0.79 8.7 0.1 2.4 2 1 0 2 2 2 0 FMN-dependent dehydrogenase HMGL-like PF00682.19 EMT53982.1 - 0.032 13.8 0.2 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 HMGL-like His_biosynth PF00977.21 EMT53982.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Fer4_8 PF13183.6 EMT53982.1 - 3.3 8.2 13.9 14 6.2 13.9 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 EMT53982.1 - 4.4 8.3 15.1 5e+02 1.7 15.1 2.5 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_13 PF13370.6 EMT53982.1 - 8.6 7.0 13.9 13 6.4 4.0 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 EMT53982.1 - 8.8 7.3 14.5 8.6 7.3 2.6 2.4 1 1 3 4 4 4 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 EMT53983.1 - 1.1e-38 131.5 2.1 1.6e-38 130.9 2.1 1.2 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 EMT53983.1 - 4.3e-33 114.8 3.6 7e-33 114.1 3.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMT53983.1 - 3.7e-14 53.0 3.3 5e-07 30.2 0.6 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT53983.1 - 1.3e-12 47.6 0.4 3.5e-06 26.5 0.0 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMT53983.1 - 2.2e-09 37.4 0.2 2.2e-09 37.4 0.2 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EMT53983.1 - 2e-08 33.8 0.5 0.00024 20.5 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EMT53983.1 - 1.2e-07 31.7 6.8 8.7e-07 28.8 0.8 2.6 1 1 1 3 3 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EMT53983.1 - 1.5e-06 27.6 1.3 0.00065 18.9 0.2 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EMT53983.1 - 1.5e-06 27.7 1.2 1.7e-06 27.5 0.2 1.5 2 0 0 2 2 1 1 FAD binding domain Amino_oxidase PF01593.24 EMT53983.1 - 1.7e-06 27.6 0.2 1.7e-06 27.6 0.2 2.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EMT53983.1 - 1.7e-06 27.7 5.5 1.8e-06 27.6 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMT53983.1 - 1.2e-05 24.2 2.3 2.2e-05 23.3 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EMT53983.1 - 1.8e-05 24.1 2.3 5.3e-05 22.6 0.3 2.2 1 1 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 EMT53983.1 - 2.7e-05 23.6 0.3 0.0061 15.9 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.19 EMT53983.1 - 2.7e-05 22.8 0.0 0.06 11.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like FAD_binding_2 PF00890.24 EMT53983.1 - 5.1e-05 22.5 0.6 5.1e-05 22.5 0.6 2.6 2 1 1 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 EMT53983.1 - 6.9e-05 23.2 0.4 0.02 15.3 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding YjeF_N PF03853.15 EMT53983.1 - 7.9e-05 22.6 0.2 0.014 15.3 0.1 3.2 3 0 0 3 3 3 1 YjeF-related protein N-terminus PALP PF00291.25 EMT53983.1 - 0.00027 20.5 0.2 0.18 11.2 0.0 2.2 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Lycopene_cycl PF05834.12 EMT53983.1 - 0.0019 17.3 0.4 0.0047 16.0 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EMT53983.1 - 0.0034 17.4 0.1 0.0082 16.1 0.1 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EMT53983.1 - 0.0086 16.1 0.2 2.1 8.4 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.6 EMT53983.1 - 0.0094 16.4 0.9 0.082 13.4 0.0 2.5 3 0 0 3 3 2 1 XdhC Rossmann domain Oxidored_nitro PF00148.19 EMT53983.1 - 0.027 13.2 0.1 1.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase F420_oxidored PF03807.17 EMT53983.1 - 0.052 14.1 0.7 3.3 8.3 0.2 3.6 4 1 0 4 4 2 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.14 EMT53983.1 - 0.062 12.1 0.1 0.062 12.1 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Fer4_7 PF12838.7 EMT53983.1 - 0.07 13.7 0.5 0.07 13.7 0.5 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain TrkA_N PF02254.18 EMT53983.1 - 0.072 13.4 0.3 0.23 11.7 0.0 2.0 2 0 0 2 2 1 0 TrkA-N domain K_oxygenase PF13434.6 EMT53983.1 - 0.098 11.8 0.1 3.5 6.7 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 EMT53983.1 - 0.11 12.3 1.1 0.17 11.7 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tryp_inh PF17983.1 EMT53983.1 - 0.12 12.5 1.3 0.27 11.4 1.3 1.6 1 0 0 1 1 1 0 Trypsin inhibitors 1,2 and 3 Fer4_9 PF13187.6 EMT53983.1 - 0.15 12.2 0.3 0.15 12.2 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain AdoHcyase_NAD PF00670.21 EMT53983.1 - 0.22 11.6 2.6 2.4 8.2 0.1 2.9 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fer4_18 PF13746.6 EMT53983.1 - 0.35 11.1 2.5 0.32 11.2 0.2 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMT53983.1 - 1.9 8.6 9.9 13 6.0 9.7 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain ATP_sub_h PF10775.9 EMT53985.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase complex subunit h PLDc_N PF13396.6 EMT53987.1 - 1.2e-05 25.1 0.2 1.2e-05 25.1 0.2 2.2 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal BCD PF15461.6 EMT53987.1 - 0.0016 18.0 1.0 0.0018 17.8 1.0 1.0 1 0 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase DUF456 PF04306.13 EMT53987.1 - 0.0023 18.2 0.3 0.0026 18.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Glucos_trans_II PF14264.6 EMT53987.1 - 0.0026 17.2 1.9 0.0031 16.9 1.9 1.1 1 0 0 1 1 1 1 Glucosyl transferase GtrII HisKA_7TM PF16927.5 EMT53987.1 - 0.0078 16.3 1.8 0.0083 16.2 1.8 1.0 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase NapE PF06796.11 EMT53987.1 - 0.012 15.1 1.3 0.029 13.9 0.0 2.0 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE DUF4281 PF14108.6 EMT53987.1 - 0.013 15.9 0.3 0.024 15.0 0.2 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4281) DUF4018 PF13210.6 EMT53987.1 - 0.49 10.1 6.3 0.92 9.3 6.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4018) MpPF26 PF07666.11 EMT53987.1 - 0.6 10.2 6.3 3.3 7.8 6.4 1.8 1 1 0 1 1 1 0 M penetrans paralogue family 26 DUF4234 PF14018.6 EMT53987.1 - 0.99 9.6 6.8 3.1 8.0 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) Sid-5 PF17204.3 EMT53987.1 - 8.9 6.6 6.0 9.4 6.5 0.8 2.1 1 1 1 2 2 2 0 Sid-5 family Aminotran_3 PF00202.21 EMT53988.1 - 9.4e-110 367.0 0.0 1.1e-109 366.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EMT53988.1 - 1.1e-07 31.5 0.0 2.6e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EMT53988.1 - 0.052 12.7 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II Prim-Pol PF09250.11 EMT53988.1 - 0.064 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Aldedh PF00171.22 EMT53989.1 - 4e-150 500.4 0.0 4.5e-150 500.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PucR PF07905.11 EMT53990.1 - 1.4e-33 115.7 0.0 2.4e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 EMT53990.1 - 1.1e-21 76.3 2.6 4.6e-21 74.4 2.0 2.1 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 EMT53990.1 - 2.6e-05 24.5 0.0 6.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 GGDEF-like domain HTH_8 PF02954.19 EMT53990.1 - 0.023 14.5 0.9 0.14 12.0 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 EMT53990.1 - 0.079 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Peptidase_S8 PF00082.22 EMT53991.1 - 8e-44 150.1 0.0 1.5e-43 149.2 0.0 1.4 1 0 0 1 1 1 1 Subtilase family PPC PF04151.15 EMT53991.1 - 6.9e-06 27.1 0.0 0.052 14.7 0.0 3.2 2 0 0 2 2 2 2 Bacterial pre-peptidase C-terminal domain ABC_tran PF00005.27 EMT53992.1 - 9.5e-34 116.9 0.0 1.4e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT53992.1 - 4.9e-19 68.6 0.2 7.9e-19 67.9 0.2 1.3 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EMT53992.1 - 1.1e-08 35.3 0.0 8.7e-06 25.8 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMT53992.1 - 0.0059 17.0 0.1 0.0091 16.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT53992.1 - 0.0065 16.7 1.1 0.046 14.0 1.1 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EMT53992.1 - 0.02 14.3 0.5 0.19 11.2 0.5 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.25 EMT53992.1 - 0.034 13.8 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 EMT53992.1 - 0.1 12.3 0.1 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 EMT53992.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EMT53992.1 - 0.24 11.2 0.2 0.42 10.4 0.2 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.6 EMT53992.1 - 0.32 9.6 1.3 0.48 9.0 1.3 1.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMT53993.1 - 4.7e-30 104.9 0.0 6.6e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT53993.1 - 3.1e-17 62.8 0.0 5.5e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EMT53993.1 - 6.6e-05 22.5 0.1 0.00014 21.4 0.1 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT53993.1 - 8.3e-05 22.5 1.5 0.00036 20.4 0.1 2.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 EMT53993.1 - 0.0012 18.5 0.0 0.0013 18.4 0.0 1.3 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 EMT53993.1 - 0.005 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EMT53993.1 - 0.012 15.9 1.2 0.72 10.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMT53993.1 - 0.022 15.1 0.1 0.04 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EMT53993.1 - 0.025 14.6 0.1 0.056 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EMT53993.1 - 0.031 14.7 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EMT53993.1 - 0.039 13.5 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EMT53993.1 - 0.045 13.5 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 EMT53993.1 - 0.066 12.8 0.1 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EMT53993.1 - 0.07 12.8 0.1 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 EMT53993.1 - 0.096 13.1 0.3 0.27 11.7 0.3 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EMT53993.1 - 0.1 11.9 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 EMT53993.1 - 0.12 11.8 0.1 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 EMT53993.1 - 0.12 11.8 0.4 1.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein DUF87 PF01935.17 EMT53993.1 - 0.15 12.1 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_ATPase PF09818.9 EMT53993.1 - 0.19 10.5 0.3 0.48 9.2 0.3 1.7 1 1 0 1 1 1 0 Predicted ATPase of the ABC class AAA_15 PF13175.6 EMT53993.1 - 0.26 11.0 0.1 4.1 7.0 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain BPD_transp_1 PF00528.22 EMT53994.1 - 2.4e-28 99.1 8.0 2.8e-28 98.9 4.9 2.1 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT53994.1 - 2.4e-14 53.0 1.0 2.4e-14 53.0 1.0 2.8 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C DUF4731 PF15875.5 EMT53994.1 - 0.44 10.8 3.2 25 5.1 0.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4731) BPD_transp_1 PF00528.22 EMT53995.1 - 2.9e-44 151.0 14.5 1.7e-41 142.0 15.1 2.1 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component DUF3593 PF12159.8 EMT53995.1 - 0.27 11.3 4.7 2.2 8.4 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3593) T_cell_tran_alt PF15128.6 EMT53995.1 - 4 7.3 6.6 2 8.3 1.7 2.7 3 0 0 3 3 3 0 T-cell leukemia translocation-altered SBP_bac_5 PF00496.22 EMT53996.1 - 5.5e-87 292.2 4.4 9.6e-87 291.4 4.4 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BES1_N PF05687.13 EMT53996.1 - 0.032 14.6 0.4 0.33 11.3 0.0 2.5 3 0 0 3 3 3 0 BES1/BZR1 plant transcription factor, N-terminal UBA_4 PF14555.6 EMT53996.1 - 0.041 13.7 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain SPDY PF03771.16 EMT53996.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF317) AAA PF00004.29 EMT53997.1 - 4.6e-34 117.7 0.0 5.7e-17 62.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EMT53997.1 - 2.1e-23 82.3 3.2 3.9e-11 43.0 0.1 3.2 2 0 0 2 2 2 2 AAA lid domain AAA_22 PF13401.6 EMT53997.1 - 4.1e-12 46.5 0.2 0.0057 16.9 0.0 4.7 2 2 2 4 4 4 2 AAA domain RuvB_N PF05496.12 EMT53997.1 - 4.5e-09 36.3 0.1 0.0018 18.1 0.0 3.3 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EMT53997.1 - 4.6e-09 36.4 0.4 0.00065 19.7 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMT53997.1 - 4.7e-08 32.7 1.5 0.017 14.5 0.0 4.3 2 2 1 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EMT53997.1 - 6.3e-08 33.2 8.9 0.0011 19.4 0.2 4.0 3 2 0 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 EMT53997.1 - 1e-07 31.8 0.5 0.0042 16.8 0.0 4.2 2 2 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 EMT53997.1 - 6.4e-07 29.3 1.0 0.045 13.5 0.2 3.5 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EMT53997.1 - 2.2e-06 28.3 1.2 0.09 13.3 0.0 3.8 4 1 1 5 5 2 2 AAA domain RNA_helicase PF00910.22 EMT53997.1 - 1.2e-05 25.7 0.0 0.14 12.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase NTPase_1 PF03266.15 EMT53997.1 - 2e-05 24.6 0.7 0.043 13.7 0.1 3.0 2 1 1 3 3 3 2 NTPase AAA_33 PF13671.6 EMT53997.1 - 2.4e-05 24.5 0.6 0.31 11.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.14 EMT53997.1 - 3.1e-05 24.2 0.0 0.0043 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 EMT53997.1 - 4.2e-05 23.9 1.2 0.49 10.7 0.3 3.5 3 1 0 3 3 2 2 AAA domain ABC_tran PF00005.27 EMT53997.1 - 6.1e-05 23.5 0.1 0.025 15.1 0.0 2.9 3 0 0 3 3 2 1 ABC transporter Zeta_toxin PF06414.12 EMT53997.1 - 0.00022 20.6 0.2 0.36 10.1 0.0 3.5 3 1 0 3 3 3 1 Zeta toxin Torsin PF06309.11 EMT53997.1 - 0.00026 21.1 0.1 0.21 11.7 0.0 3.3 3 0 0 3 3 3 1 Torsin Viral_helicase1 PF01443.18 EMT53997.1 - 0.00067 19.5 0.0 0.089 12.5 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 EMT53997.1 - 0.0016 18.2 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EMT53997.1 - 0.0019 18.1 0.2 0.91 9.4 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.6 EMT53997.1 - 0.0026 18.2 0.5 3.6 8.0 0.1 3.6 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 EMT53997.1 - 0.0026 18.0 12.3 0.15 12.3 0.0 4.7 5 1 0 5 5 4 2 AAA domain KTI12 PF08433.10 EMT53997.1 - 0.0028 17.2 0.0 2.6 7.4 0.0 2.6 2 0 0 2 2 2 2 Chromatin associated protein KTI12 ResIII PF04851.15 EMT53997.1 - 0.003 17.6 0.0 0.92 9.5 0.0 2.9 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EMT53997.1 - 0.0042 17.1 0.0 1 9.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EMT53997.1 - 0.0046 16.5 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region MCM PF00493.23 EMT53997.1 - 0.0053 15.9 0.0 0.17 11.0 0.0 2.6 2 0 0 2 2 2 1 MCM P-loop domain Thymidylate_kin PF02223.17 EMT53997.1 - 0.0099 15.6 0.7 6.6 6.4 0.0 3.0 3 0 0 3 3 2 0 Thymidylate kinase TsaE PF02367.17 EMT53997.1 - 0.013 15.5 0.0 1.4 8.9 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EMT53997.1 - 0.016 14.8 2.4 11 5.6 0.1 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.6 EMT53997.1 - 0.017 15.2 0.0 0.59 10.3 0.0 3.0 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.13 EMT53997.1 - 0.02 14.1 0.3 0.74 8.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) DUF2075 PF09848.9 EMT53997.1 - 0.024 13.9 3.0 3.1 6.9 0.2 3.6 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) Guanylate_cyc_2 PF09778.9 EMT53997.1 - 0.024 14.0 0.0 0.6 9.4 0.0 2.2 2 0 0 2 2 2 0 Guanylylate cyclase AAA_11 PF13086.6 EMT53997.1 - 0.027 14.2 0.0 6.9 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMT53997.1 - 0.031 13.9 5.9 5.3 6.6 0.0 4.4 3 2 1 4 4 4 0 AAA domain AAA_3 PF07726.11 EMT53997.1 - 0.032 14.1 0.1 5.1 7.0 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EMT53997.1 - 0.034 13.6 1.1 13 5.2 0.1 3.1 2 1 1 3 3 3 0 PhoH-like protein ATPase PF06745.13 EMT53997.1 - 0.038 13.3 0.1 3.2 7.0 0.0 2.6 2 0 0 2 2 2 0 KaiC APS_kinase PF01583.20 EMT53997.1 - 0.044 13.7 0.0 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 EMT53997.1 - 0.062 12.5 0.1 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.13 EMT53997.1 - 0.062 12.5 0.0 8.9 5.4 0.0 3.1 2 1 1 3 3 3 0 TIP49 P-loop domain MMR_HSR1 PF01926.23 EMT53997.1 - 0.071 13.2 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EMT53997.1 - 0.078 12.7 0.3 8.7 6.0 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 EMT53997.1 - 0.11 11.6 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 EMT53997.1 - 0.13 12.0 0.0 23 4.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain CbiA PF01656.23 EMT53997.1 - 0.19 11.8 0.8 28 4.8 0.0 3.1 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1059 PF06348.11 EMT53998.1 - 0.094 13.0 0.2 0.13 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) EMP24_GP25L PF01105.24 EMT54003.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD EamA PF00892.20 EMT54004.1 - 4.3e-50 169.4 43.9 5.6e-25 88.1 19.0 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EMT54004.1 - 0.00083 18.8 14.1 0.003 16.9 14.1 1.8 1 1 0 1 1 1 1 Triose-phosphate Transporter family FCD PF07729.12 EMT54005.1 - 7.2e-21 74.9 5.3 9.8e-21 74.5 4.8 1.4 1 1 0 1 1 1 1 FCD domain GntR PF00392.21 EMT54005.1 - 4.1e-15 55.2 0.0 4.1e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EMT54005.1 - 5.3e-05 22.7 0.0 0.00097 18.7 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EMT54005.1 - 6.1e-05 22.8 0.0 0.00053 19.8 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EMT54005.1 - 0.0018 18.6 0.0 0.02 15.2 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator MarR_2 PF12802.7 EMT54005.1 - 0.0043 16.9 0.2 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 EMT54005.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.10 EMT54005.1 - 0.012 15.4 0.0 0.036 13.9 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 EMT54005.1 - 0.03 14.3 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain LexA_DNA_bind PF01726.16 EMT54005.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain HTH_AsnC-type PF13404.6 EMT54005.1 - 0.11 12.4 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_28 PF13518.6 EMT54005.1 - 0.11 12.6 0.1 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 EMT54005.1 - 0.12 12.3 0.0 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 TFIIE alpha subunit Fe_dep_repress PF01325.19 EMT54005.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DNA_topoisoIV PF00521.20 EMT54007.1 - 2.7e-145 484.5 4.0 3.6e-145 484.1 4.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 EMT54007.1 - 3.6e-28 96.8 1.0 6.3e-12 44.8 0.1 5.5 5 0 0 5 5 5 5 DNA gyrase C-terminal domain, beta-propeller HAP1_N PF04849.13 EMT54007.1 - 0.00065 19.0 2.9 0.0012 18.1 2.9 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF1803 PF08820.10 EMT54007.1 - 0.013 15.6 0.4 0.48 10.5 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) RPW8 PF05659.11 EMT54007.1 - 0.035 13.8 3.1 0.091 12.4 3.1 1.6 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3573 PF12097.8 EMT54007.1 - 0.11 11.4 0.2 0.17 10.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HIP1_clath_bdg PF16515.5 EMT54007.1 - 1.3 9.7 5.5 1.7 9.3 3.4 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DNA_gyraseB PF00204.25 EMT54008.1 - 1.4e-57 194.0 0.2 2.2e-57 193.3 0.2 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 EMT54008.1 - 5.5e-30 103.3 0.1 1.2e-29 102.3 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 EMT54008.1 - 3e-18 66.4 0.2 6.9e-18 65.2 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EMT54008.1 - 1.9e-14 53.7 0.0 3.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain TOPRIM_C PF16898.5 EMT54008.1 - 0.061 13.6 0.0 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 C-terminal associated domain of TOPRIM HATPase_c_3 PF13589.6 EMT54008.1 - 0.067 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ThiF PF00899.21 EMT54009.1 - 3e-17 62.8 0.0 3.9e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family YflT PF11181.8 EMT54011.1 - 9.2e-20 71.0 0.2 1.2e-19 70.7 0.2 1.1 1 0 0 1 1 1 1 Heat induced stress protein YflT DUF1292 PF06949.11 EMT54012.1 - 4e-06 27.7 14.7 4.7e-06 27.5 14.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1292) Spore_Cse60 PF10957.8 EMT54012.1 - 3.1 7.9 6.3 1.1 9.3 2.6 2.2 2 1 1 3 3 3 0 Sporulation protein Cse60 HATPase_c PF02518.26 EMT54013.1 - 4.3e-25 88.4 0.0 1e-24 87.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMT54013.1 - 1.4e-16 60.3 0.2 4.6e-16 58.6 0.0 2.0 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 EMT54013.1 - 1.3e-08 35.1 0.0 0.00096 19.4 0.0 2.8 2 1 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EMT54013.1 - 1.2e-07 32.0 0.0 1.8e-05 24.9 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 EMT54013.1 - 2.8e-07 30.4 0.0 1.8e-06 27.8 0.0 2.4 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 EMT54013.1 - 0.0001 22.3 0.0 0.00052 20.0 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 EMT54013.1 - 0.00011 22.4 0.0 0.00052 20.3 0.0 2.2 2 0 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.6 EMT54013.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 EMT54013.1 - 0.00017 21.5 0.0 0.00056 19.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HPTransfase PF10090.9 EMT54013.1 - 0.00034 20.4 0.0 0.0014 18.5 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphotransferase C-terminal domain RolB_RolC PF02027.17 EMT54013.1 - 0.005 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 RolB/RolC glucosidase family ABC2_membrane_2 PF12679.7 EMT54015.1 - 3.4e-14 52.8 19.7 5.8e-14 52.1 19.7 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 EMT54015.1 - 2.2e-06 27.1 26.5 2.2e-06 27.1 26.5 1.6 1 1 1 2 2 2 1 ABC-2 family transporter protein Ost4 PF10215.9 EMT54015.1 - 0.12 12.2 0.3 0.12 12.2 0.3 2.6 2 0 0 2 2 2 0 Oligosaccaryltransferase ABC_tran PF00005.27 EMT54016.1 - 2.9e-27 95.9 0.0 4.4e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT54016.1 - 1.6e-11 44.5 0.5 4.8e-06 26.6 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EMT54016.1 - 0.00018 21.4 0.0 0.012 15.3 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EMT54016.1 - 0.0026 18.3 0.1 0.0054 17.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMT54016.1 - 0.0031 17.2 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT54016.1 - 0.0037 17.5 0.5 0.031 14.5 0.5 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EMT54016.1 - 0.015 14.7 0.1 3.3 7.1 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 EMT54016.1 - 0.029 15.1 0.0 0.055 14.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) AAA_27 PF13514.6 EMT54016.1 - 0.059 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMT54016.1 - 0.08 12.6 0.0 0.22 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain MukB PF04310.12 EMT54016.1 - 0.15 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 MukB N-terminal Rad17 PF03215.15 EMT54016.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain PD40 PF07676.12 EMT54018.1 - 3.8e-06 26.7 2.0 0.11 12.5 0.0 4.6 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat RskA PF10099.9 EMT54018.1 - 0.00014 22.2 0.4 0.00027 21.3 0.2 1.6 2 0 0 2 2 2 1 Anti-sigma-K factor rskA DPPIV_N PF00930.21 EMT54018.1 - 0.0011 17.8 1.5 0.19 10.4 0.1 3.4 1 1 1 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region ANAPC4_WD40 PF12894.7 EMT54018.1 - 0.0021 18.3 0.1 1.1 9.7 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Sigma70_r2 PF04542.14 EMT54019.1 - 1e-12 47.6 2.8 1e-12 47.6 1.0 1.9 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EMT54019.1 - 1.2e-10 40.7 0.9 1.9e-10 40.1 0.9 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EMT54019.1 - 4.9e-10 38.9 0.6 7.6e-10 38.3 0.6 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 DUF722 PF05263.11 EMT54019.1 - 0.01 16.1 0.2 0.015 15.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF722) UPF0122 PF04297.14 EMT54019.1 - 0.012 15.8 0.1 0.023 14.9 0.1 1.5 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_ECF PF07638.11 EMT54019.1 - 0.05 13.5 1.2 0.27 11.1 1.2 2.0 1 1 0 1 1 1 0 ECF sigma factor Cys_Met_Meta_PP PF01053.20 EMT54020.1 - 1.8e-116 388.8 0.0 2.1e-116 388.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EMT54020.1 - 2.2e-06 27.1 0.0 3.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMT54020.1 - 4.5e-06 25.9 0.0 7.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EMT54020.1 - 5.4e-06 25.2 0.1 1.4e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 EMT54020.1 - 0.00035 19.9 0.0 0.002 17.5 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.13 EMT54020.1 - 0.019 13.9 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Response_reg PF00072.24 EMT54021.1 - 3.1e-32 111.1 1.1 3.4e-32 110.9 1.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.19 EMT54021.1 - 0.037 14.1 0.1 0.081 13.0 0.1 1.5 1 1 1 2 2 2 0 B12 binding domain Pro_isomerase PF00160.21 EMT54022.1 - 1.8e-45 155.0 0.8 2.7e-45 154.5 0.8 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WH2 PF02205.20 EMT54023.1 - 1.5 8.8 4.5 0.24 11.3 0.6 1.8 2 0 0 2 2 2 0 WH2 motif YlaH PF14036.6 EMT54024.1 - 1.2 9.5 13.9 1.1 9.6 3.3 3.0 2 1 0 2 2 2 0 YlaH-like protein Hydrolase_2 PF07486.12 EMT54025.1 - 2.7e-30 105.3 0.1 4.5e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 Cell Wall Hydrolase DUF359 PF04019.12 EMT54025.1 - 0.18 11.5 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF359) adh_short_C2 PF13561.6 EMT54026.1 - 4.1e-67 226.2 1.6 4.8e-67 225.9 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT54026.1 - 1.6e-61 207.2 0.6 1.9e-61 206.9 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT54026.1 - 1.6e-09 37.9 1.8 2.2e-09 37.5 1.8 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EMT54026.1 - 0.00051 19.4 0.1 0.00094 18.5 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EMT54026.1 - 0.0085 15.6 0.2 0.014 14.9 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EMT54026.1 - 0.015 14.6 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EMT54026.1 - 0.033 14.8 0.4 0.073 13.7 0.4 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EMT54026.1 - 0.076 12.7 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EMT54026.1 - 0.13 12.7 1.2 0.2 12.1 1.2 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF1811 PF08838.10 EMT54027.1 - 3.6e-29 100.9 0.0 4.1e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1811) CdiI_4 PF18624.1 EMT54027.1 - 0.1 13.1 0.2 0.13 12.8 0.2 1.1 1 0 0 1 1 1 0 CDI immunity protein DUF441 PF04284.13 EMT54028.1 - 4.3e-47 159.6 21.1 5.3e-47 159.3 21.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF441) Fe-S_biosyn PF01521.20 EMT54029.1 - 1.3e-07 31.8 0.0 1.6e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF2515 PF10720.9 EMT54030.1 - 3.4e-109 364.8 0.1 4.1e-109 364.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2515) Prenyltrans PF00432.21 EMT54031.1 - 0.06 13.1 0.1 0.84 9.4 0.0 2.6 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat DUF1444 PF07285.11 EMT54032.1 - 8.3e-52 176.4 0.0 1e-51 176.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1444) DUF3900 PF13039.6 EMT54033.1 - 9.4e-113 376.3 1.0 1.2e-112 376.0 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3900) DUF3898 PF13037.6 EMT54033.1 - 1.1e-38 131.2 0.1 2.2e-38 130.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3898) YecM PF06185.12 EMT54033.1 - 0.29 10.8 4.7 0.63 9.7 0.9 2.6 2 1 1 3 3 3 0 YecM protein Pkinase PF00069.25 EMT54034.1 - 5.3e-27 94.8 0.0 6.7e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMT54034.1 - 2.7e-15 56.4 0.0 3.5e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMT54034.1 - 5.8e-06 26.4 0.1 0.00018 21.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EMT54034.1 - 0.00076 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EMT54034.1 - 0.0044 16.7 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family DUF4135 PF13575.6 EMT54034.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Kinase-like PF14531.6 EMT54034.1 - 0.078 12.3 0.0 0.95 8.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 EMT54034.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CCDC-167 PF15188.6 EMT54035.1 - 0.025 14.9 0.6 0.028 14.8 0.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DEAD PF00270.29 EMT54036.1 - 2.3e-43 148.0 0.2 3.8e-43 147.3 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMT54036.1 - 1.5e-28 99.3 0.0 2.6e-27 95.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMT54036.1 - 2.9e-10 40.4 0.0 4.8e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMT54036.1 - 8.2e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 EMT54036.1 - 0.00015 21.1 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 EMT54036.1 - 0.00018 20.9 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EMT54036.1 - 0.0015 18.9 0.1 0.0025 18.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 EMT54036.1 - 0.004 16.8 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase CMS1 PF14617.6 EMT54036.1 - 0.0078 15.6 0.4 0.013 14.8 0.4 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_11 PF13086.6 EMT54036.1 - 0.0084 15.9 0.2 0.065 13.0 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMT54036.1 - 0.0098 16.2 0.5 0.027 14.7 0.2 1.9 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 EMT54036.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Helicase THF_DHG_CYH_C PF02882.19 EMT54036.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain eIF-3c_N PF05470.12 EMT54037.1 - 0.05 11.9 2.5 0.047 12.0 2.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NAGPA PF09992.9 EMT54038.1 - 2.2e-37 128.8 0.5 3.2e-37 128.3 0.5 1.2 1 0 0 1 1 1 1 Phosphodiester glycosidase ubiquitin PF00240.23 EMT54038.1 - 0.16 11.8 0.1 62 3.4 0.0 3.7 5 0 0 5 5 5 0 Ubiquitin family ABC_tran PF00005.27 EMT54040.1 - 4.4e-46 156.8 1.5 3.4e-25 89.1 0.0 3.1 3 1 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EMT54040.1 - 3.8e-26 90.9 6.4 3.8e-26 90.9 6.4 1.7 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EMT54040.1 - 1e-14 55.1 0.1 0.012 15.5 0.1 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT54040.1 - 1.7e-12 47.3 0.8 0.00024 20.6 0.0 4.6 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMT54040.1 - 4.4e-08 32.7 0.4 0.0061 16.3 0.0 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT54040.1 - 2.6e-07 31.2 0.0 0.0067 16.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EMT54040.1 - 2.3e-06 27.6 0.0 0.013 15.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 EMT54040.1 - 7.6e-06 26.5 0.8 0.038 14.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EMT54040.1 - 1.9e-05 25.0 0.3 0.47 10.9 0.1 3.4 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 EMT54040.1 - 4.5e-05 23.7 1.6 1.5 9.1 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EMT54040.1 - 4.8e-05 23.7 0.9 0.005 17.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EMT54040.1 - 5e-05 22.4 2.0 0.14 11.1 0.0 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EMT54040.1 - 6.5e-05 22.9 0.0 0.056 13.4 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EMT54040.1 - 0.00019 22.0 10.0 1.9 9.0 0.6 4.0 4 0 0 4 4 4 2 AAA domain AAA_14 PF13173.6 EMT54040.1 - 0.00028 20.9 0.4 5 7.2 0.1 3.8 4 0 0 4 4 4 0 AAA domain MukB PF04310.12 EMT54040.1 - 0.00029 20.7 0.2 0.0068 16.2 0.0 2.6 2 0 0 2 2 2 1 MukB N-terminal AAA_7 PF12775.7 EMT54040.1 - 0.00037 20.1 0.1 0.77 9.2 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 EMT54040.1 - 0.00085 19.1 0.9 0.53 10.0 0.1 3.5 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 EMT54040.1 - 0.0015 18.7 3.3 0.79 9.9 0.1 3.5 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 EMT54040.1 - 0.0049 16.8 0.0 0.68 9.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 EMT54040.1 - 0.0059 16.7 7.3 0.56 10.3 0.0 3.4 3 1 1 4 4 4 2 Helicase HerA, central domain AAA_30 PF13604.6 EMT54040.1 - 0.0065 16.2 2.9 0.53 10.0 0.2 2.8 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EMT54040.1 - 0.01 15.1 9.0 0.073 12.2 1.7 3.9 2 2 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 EMT54040.1 - 0.017 14.3 0.2 9.8 5.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Ploopntkinase3 PF18751.1 EMT54040.1 - 0.028 14.3 0.6 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 EMT54040.1 - 0.041 13.9 1.5 5.1 7.1 0.0 3.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 EMT54040.1 - 0.08 12.3 1.1 2.2 7.6 0.2 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 EMT54040.1 - 0.085 12.6 0.0 20 4.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EMT54040.1 - 0.089 12.2 1.6 4 6.7 0.3 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Septin PF00735.18 EMT54040.1 - 0.093 12.0 1.5 3.9 6.7 0.5 2.4 2 0 0 2 2 2 0 Septin TCL1_MTCP1 PF01840.17 EMT54040.1 - 0.098 12.3 0.4 0.86 9.3 0.0 2.2 2 0 0 2 2 2 0 TCL1/MTCP1 family AAA_15 PF13175.6 EMT54040.1 - 0.14 11.9 10.4 2.4 7.8 0.0 3.8 2 1 0 2 2 2 0 AAA ATPase domain MobB PF03205.14 EMT54040.1 - 0.15 12.0 0.5 26 4.7 0.2 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 EMT54040.1 - 0.16 11.6 3.1 9 5.8 0.1 3.3 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EMT54040.1 - 0.18 11.7 3.2 2.7 7.9 0.2 3.2 3 0 0 3 3 3 0 NTPase Roc PF08477.13 EMT54040.1 - 0.18 12.0 3.3 4 7.7 0.8 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 EMT54040.1 - 0.19 11.3 4.8 6.8 6.3 0.1 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.25 EMT54040.1 - 0.26 10.9 1.1 12 5.5 0.1 2.6 2 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 EMT54040.1 - 0.35 11.3 3.9 6.3 7.2 0.2 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EMT54040.1 - 0.62 10.5 5.6 5.2 7.5 0.1 3.0 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 EMT54040.1 - 0.73 9.6 5.4 3 7.6 0.2 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EMT54040.1 - 0.84 9.7 6.4 3.5 7.7 0.0 3.4 3 1 1 4 4 4 0 Dynamin family ABC_tran_CTD PF16326.5 EMT54040.1 - 1.6 9.0 9.3 0.38 11.0 2.2 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain HEPN_Apea PF18739.1 EMT54041.1 - 6.3e-18 65.1 0.1 1.7e-17 63.7 0.1 1.7 1 0 0 1 1 1 1 Apea-like HEPN SspP PF08179.12 EMT54042.1 - 5e-06 26.9 4.3 6.8e-06 26.4 4.3 1.4 1 1 0 1 1 1 1 Small acid-soluble spore protein P family SpoOE-like PF09388.10 EMT54044.1 - 1.3e-11 44.1 0.1 1.7e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Spo0E like sporulation regulatory protein Pyr_redox_2 PF07992.14 EMT54045.1 - 3.6e-70 236.5 7.4 6.3e-70 235.7 7.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EMT54045.1 - 2.3e-38 130.8 0.2 8.1e-38 129.1 0.2 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EMT54045.1 - 1.5e-21 76.7 13.6 3.3e-20 72.4 2.2 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT54045.1 - 5e-13 49.0 2.4 4.8e-08 32.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMT54045.1 - 3.3e-10 39.6 5.2 6.1e-08 32.2 2.0 2.8 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EMT54045.1 - 6.9e-08 32.3 1.0 6.9e-08 32.3 1.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMT54045.1 - 1.1e-07 31.3 15.3 1.6e-07 30.8 2.2 3.9 3 1 1 4 4 4 1 FAD binding domain HI0933_like PF03486.14 EMT54045.1 - 8.8e-07 28.0 11.9 0.00011 21.1 1.7 3.3 2 1 1 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 EMT54045.1 - 1e-05 25.7 2.5 0.0003 21.0 0.5 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMT54045.1 - 1.1e-05 25.1 10.9 0.014 15.0 0.6 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMT54045.1 - 2.5e-05 23.7 13.2 0.0032 16.8 1.3 3.2 2 1 1 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 EMT54045.1 - 0.00048 19.5 12.8 0.089 12.1 0.4 3.4 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EMT54045.1 - 0.00095 18.8 0.9 0.00095 18.8 0.9 3.2 3 1 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EMT54045.1 - 0.003 17.5 5.3 0.0044 16.9 0.5 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 EMT54045.1 - 0.0041 16.4 3.8 0.052 12.8 0.2 2.7 2 1 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 EMT54045.1 - 0.0068 16.8 2.7 0.48 10.9 0.2 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EMT54045.1 - 0.13 11.3 6.1 2 7.4 0.1 2.6 2 1 0 2 2 2 0 Lycopene cyclase protein DUF2264 PF10022.9 EMT54045.1 - 0.22 10.6 0.0 0.32 10.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Trp_halogenase PF04820.14 EMT54045.1 - 0.89 8.3 5.3 0.068 12.0 0.4 1.6 2 0 0 2 2 2 0 Tryptophan halogenase 2-oxoacid_dh PF00198.23 EMT54046.1 - 8.9e-92 306.7 0.1 1.3e-91 306.2 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EMT54046.1 - 3.8e-23 81.1 1.3 1e-22 79.7 1.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EMT54046.1 - 4.9e-16 58.8 0.4 3.5e-15 56.1 0.4 2.4 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EMT54046.1 - 3.7e-07 29.9 3.6 0.01 15.6 0.1 2.9 3 0 0 3 3 3 2 Biotin-lipoyl like PTS_EIIA_1 PF00358.20 EMT54046.1 - 0.0089 15.8 2.0 4.3 7.1 0.1 3.0 2 1 1 3 3 3 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 GCV_H PF01597.19 EMT54046.1 - 0.011 15.6 0.6 0.025 14.5 0.6 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.6 EMT54046.1 - 0.011 15.6 2.1 0.018 15.0 0.5 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 EMT54046.1 - 0.024 15.3 6.3 2.5 8.8 0.3 3.3 3 1 1 4 4 4 0 HlyD family secretion protein HlyD_D23 PF16576.5 EMT54046.1 - 0.046 12.9 0.2 1.4 8.1 0.0 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Transket_pyr PF02779.24 EMT54047.1 - 4.1e-41 140.6 0.0 6.2e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMT54047.1 - 2.1e-39 134.2 1.6 2.1e-39 134.2 1.6 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain Aminotran_5 PF00266.19 EMT54047.1 - 0.00064 18.8 1.0 0.00095 18.2 1.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V PFOR_II PF17147.4 EMT54047.1 - 0.0012 19.1 0.6 0.0022 18.3 0.4 1.6 1 1 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II E1_dh PF00676.20 EMT54048.1 - 6.6e-93 310.9 0.1 7.6e-93 310.7 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EMT54048.1 - 6.1e-05 22.4 0.3 0.00013 21.3 0.1 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase RNase_J_C PF17770.1 EMT54048.1 - 0.017 16.2 0.1 0.036 15.1 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain TPP_enzyme_C PF02775.21 EMT54048.1 - 0.019 14.7 5.3 0.054 13.3 1.9 2.7 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Esterase PF00756.20 EMT54049.1 - 1.4e-38 132.9 0.0 1.9e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EMT54049.1 - 0.028 13.7 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GerA PF03323.13 EMT54051.1 - 1.4e-180 600.8 0.1 1.6e-180 600.6 0.1 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein Spore_permease PF03845.13 EMT54052.1 - 1.5e-74 250.7 32.0 1.5e-74 250.7 32.0 1.5 2 0 0 2 2 2 1 Spore germination protein Spore_GerAC PF05504.11 EMT54053.1 - 5.7e-36 124.2 0.9 1.1e-35 123.2 0.9 1.5 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal Beta_elim_lyase PF01212.21 EMT54054.1 - 5.2e-96 321.4 0.4 6.4e-96 321.1 0.4 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EMT54054.1 - 4.2e-11 42.6 0.0 6.1e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMT54054.1 - 2e-07 30.6 0.5 3.9e-06 26.4 0.1 2.4 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EMT54054.1 - 0.00084 18.0 0.0 0.0011 17.6 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 EMT54054.1 - 0.004 15.8 0.1 0.044 12.4 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-III RhaA PF06134.11 EMT54054.1 - 0.063 12.4 0.1 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 L-rhamnose isomerase (RhaA) OKR_DC_1 PF01276.20 EMT54054.1 - 0.08 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Fe-S_biosyn PF01521.20 EMT54055.1 - 2.8e-06 27.5 0.6 4.2e-06 26.9 0.6 1.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis UvrD-helicase PF00580.21 EMT54056.1 - 7.8e-12 45.3 2.8 1e-07 31.8 0.5 2.7 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EMT54056.1 - 1.1e-11 45.2 0.0 5.6e-10 39.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain UvrD_C PF13361.6 EMT54056.1 - 8.4e-11 41.8 1.1 0.00027 20.4 0.0 3.2 2 1 1 3 3 3 3 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 EMT54056.1 - 9.7e-06 25.3 0.0 2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EMT54056.1 - 0.00018 21.3 0.0 0.1 12.3 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EMT54056.1 - 0.0015 17.8 0.0 0.015 14.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EMT54056.1 - 0.0015 18.2 0.1 0.056 13.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 EMT54056.1 - 0.0026 17.8 0.1 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EMT54056.1 - 0.013 14.9 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 EMT54056.1 - 0.014 15.8 0.4 0.059 13.8 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain PEP-utilisers_N PF05524.13 EMT54056.1 - 0.019 15.1 1.3 0.54 10.4 0.1 2.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DEAD PF00270.29 EMT54056.1 - 0.027 14.3 0.1 0.093 12.5 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.12 EMT54056.1 - 0.048 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 EMT54056.1 - 3.6 7.3 8.4 13 5.4 0.0 3.4 4 0 0 4 4 4 0 AAA domain RRF PF01765.19 EMT54056.1 - 9.8 6.1 7.2 18 5.2 1.6 2.5 2 0 0 2 2 2 0 Ribosome recycling factor CRCB PF02537.15 EMT54057.1 - 6.3e-24 84.1 10.4 7.7e-24 83.8 10.4 1.0 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) ABC2_membrane_5 PF13346.6 EMT54057.1 - 0.069 12.7 1.1 0.071 12.7 1.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF896 PF05979.12 EMT54058.1 - 1.1e-19 70.1 4.4 1.2e-19 69.9 4.4 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF896) Nore1-SARAH PF16517.5 EMT54058.1 - 0.0048 16.8 0.8 0.0085 16.0 0.8 1.5 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RNA_pol_A_CTD PF03118.15 EMT54058.1 - 0.031 14.0 1.8 1.3 8.8 0.5 2.4 2 1 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain DnaG_DnaB_bind PF08278.11 EMT54058.1 - 0.087 13.4 3.1 0.092 13.4 2.4 1.4 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding LysM PF01476.20 EMT54059.1 - 5.2e-08 32.8 0.1 1.8e-07 31.1 0.1 1.9 1 1 0 1 1 1 1 LysM domain LexA_DNA_bind PF01726.16 EMT54060.1 - 8.4e-29 99.2 0.1 1.2e-28 98.6 0.1 1.2 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 EMT54060.1 - 8.6e-18 64.1 0.1 1.6e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like HTH_IclR PF09339.10 EMT54060.1 - 0.0001 22.0 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EMT54060.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EMT54060.1 - 0.00015 21.2 0.0 0.00038 20.0 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 EMT54060.1 - 0.00043 20.1 0.0 0.00085 19.2 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 EMT54060.1 - 0.0096 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 EMT54060.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 EMT54060.1 - 0.017 14.9 0.1 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 EMT54060.1 - 0.023 14.6 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_20 PF12840.7 EMT54060.1 - 0.031 14.3 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 EMT54060.1 - 0.05 13.7 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain KfrA_N PF11740.8 EMT54060.1 - 0.075 13.7 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term FaeA PF04703.12 EMT54060.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 FaeA-like protein DUF456 PF04306.13 EMT54061.1 - 3.8e-36 124.4 20.8 3.8e-36 124.4 20.8 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF456) Phage_r1t_holin PF16945.5 EMT54061.1 - 0.21 11.8 1.8 0.32 11.2 0.0 2.1 3 0 0 3 3 3 0 Putative lactococcus lactis phage r1t holin DUF4269 PF14091.6 EMT54062.1 - 2.8e-54 183.5 0.0 3.3e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4269) Gln-synt_C PF00120.24 EMT54063.1 - 2.2e-138 461.0 0.0 2.6e-138 460.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EMT54063.1 - 1.8e-31 107.7 0.0 3.2e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 EMT54063.1 - 0.00052 19.8 0.0 0.016 15.0 0.0 2.4 1 1 0 1 1 1 1 Glutamine synthetase N-terminal domain MerR_1 PF13411.6 EMT54064.1 - 1.5e-19 69.9 0.1 2.3e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 EMT54064.1 - 5e-12 45.4 0.0 1.1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 MerR family regulatory protein HTH_17 PF12728.7 EMT54064.1 - 0.061 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5572 PF17733.1 EMT54064.1 - 0.069 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5572) Met_gamma_lyase PF06838.11 EMT54065.1 - 1.8e-197 655.8 0.0 2e-197 655.6 0.0 1.0 1 0 0 1 1 1 1 Methionine gamma-lyase Cys_Met_Meta_PP PF01053.20 EMT54065.1 - 2.6e-08 32.8 0.0 3.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyoxal_oxid_N PF07250.11 EMT54065.1 - 0.11 11.7 0.0 0.43 9.7 0.0 1.8 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus Aminotran_5 PF00266.19 EMT54065.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V GTP-bdg_N PF13167.6 EMT54066.1 - 2.9e-34 117.6 1.4 4.6e-34 116.9 0.2 2.0 2 0 0 2 2 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 EMT54066.1 - 2.3e-31 108.2 8.5 4.7e-31 107.2 8.5 1.6 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 EMT54066.1 - 2.4e-20 72.7 0.0 5.4e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMT54066.1 - 4.9e-07 29.8 0.9 0.0085 16.0 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase Dynamin_N PF00350.23 EMT54066.1 - 2.2e-06 27.8 0.8 0.0015 18.6 0.0 3.0 2 1 1 3 3 3 2 Dynamin family Arf PF00025.21 EMT54066.1 - 1.5e-05 24.5 7.9 3.3e-05 23.4 1.1 3.5 2 1 1 3 3 3 1 ADP-ribosylation factor family FeoB_N PF02421.18 EMT54066.1 - 1.6e-05 24.5 0.7 5.8e-05 22.7 0.1 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EMT54066.1 - 2e-05 24.2 0.0 0.051 13.1 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.19 EMT54066.1 - 0.00037 20.1 0.6 0.35 10.5 0.1 2.8 2 1 1 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EMT54066.1 - 0.00071 20.1 0.0 0.02 15.4 0.0 2.5 1 1 1 2 2 2 1 ABC transporter G-alpha PF00503.20 EMT54066.1 - 0.0024 17.1 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 EMT54066.1 - 0.0037 16.7 0.1 0.0079 15.6 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EMT54066.1 - 0.016 14.8 0.0 0.23 11.1 0.0 2.3 2 1 0 2 2 2 0 Ras family Roc PF08477.13 EMT54066.1 - 0.025 14.8 0.0 0.11 12.7 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pox_A_type_inc PF04508.12 EMT54066.1 - 0.04 13.8 1.1 0.04 13.8 1.1 2.4 2 0 0 2 2 1 0 Viral A-type inclusion protein repeat Sdh5 PF03937.16 EMT54066.1 - 0.046 13.7 0.1 1.9 8.5 0.1 2.6 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase AAA_33 PF13671.6 EMT54066.1 - 0.073 13.2 0.0 0.45 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMT54066.1 - 2.7 7.5 6.6 1.5 8.4 0.1 3.0 3 1 1 4 4 4 0 AAA domain AAA_lid_6 PF17866.1 EMT54067.1 - 3.2e-18 65.7 0.6 7.6e-18 64.5 0.6 1.7 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 EMT54067.1 - 1.3e-17 64.4 0.0 8.8e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMT54067.1 - 3e-05 23.8 0.0 0.00014 21.6 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EMT54067.1 - 0.00058 19.3 0.1 0.1 12.0 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EMT54067.1 - 0.0012 19.1 0.8 0.3 11.4 0.1 3.6 2 1 2 4 4 4 1 AAA domain Sigma54_activat PF00158.26 EMT54067.1 - 0.003 17.3 0.3 0.062 13.0 0.3 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EMT54067.1 - 0.0042 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EMT54067.1 - 0.01 15.6 0.1 0.037 13.7 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 EMT54067.1 - 0.041 14.3 0.1 0.16 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 EMT54067.1 - 0.12 11.5 0.2 1.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ribosomal_S3Ae PF01015.18 EMT54067.1 - 0.14 11.8 0.1 6.5 6.3 0.1 2.2 2 0 0 2 2 2 0 Ribosomal S3Ae family AAA_24 PF13479.6 EMT54067.1 - 0.22 11.2 0.4 2.3 7.9 0.2 2.2 1 1 1 2 2 2 0 AAA domain DUF4184 PF13803.6 EMT54068.1 - 1.3e-65 221.1 3.6 1.5e-65 220.9 3.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4184) Zn_dep_PLPC PF00882.18 EMT54068.1 - 5.8e-23 81.8 0.0 8.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Zinc dependent phospholipase C YdjM PF04307.14 EMT54068.1 - 0.016 14.5 3.6 0.074 12.3 3.6 2.1 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase DUF4536 PF15055.6 EMT54068.1 - 0.21 11.9 6.1 0.97 9.7 4.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4536) Ndc1_Nup PF09531.10 EMT54068.1 - 0.38 9.4 3.1 0.44 9.2 3.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hfq PF17209.3 EMT54069.1 - 1.6e-33 114.1 0.2 2e-33 113.8 0.2 1.1 1 0 0 1 1 1 1 Hfq protein LSM PF01423.22 EMT54069.1 - 0.0064 16.2 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain IPPT PF01715.17 EMT54070.1 - 9.6e-89 297.1 0.3 1.3e-88 296.7 0.3 1.2 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 EMT54070.1 - 4.7e-07 29.4 0.0 1.6e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Isopentenyl transferase AAA_18 PF13238.6 EMT54070.1 - 0.00057 20.4 0.4 0.17 12.5 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EMT54070.1 - 0.0012 19.1 0.0 0.0038 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT54070.1 - 0.0014 19.0 0.1 0.0027 18.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain DNA_alkylation PF08713.11 EMT54070.1 - 0.02 14.6 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 DNA alkylation repair enzyme AAA_22 PF13401.6 EMT54070.1 - 0.021 15.1 0.0 0.084 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EMT54070.1 - 0.096 13.1 0.0 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EMT54070.1 - 0.098 12.6 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SAM_MT PF04445.13 EMT54071.1 - 6.1e-18 65.1 0.0 9.1e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase PCMT PF01135.19 EMT54071.1 - 3.2e-06 27.1 0.1 9.2e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EMT54071.1 - 0.00055 20.6 0.3 0.04 14.6 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Usp PF00582.26 EMT54071.1 - 0.013 16.0 0.5 0.36 11.4 0.0 2.2 2 0 0 2 2 2 0 Universal stress protein family Methyltransf_24 PF13578.6 EMT54071.1 - 0.018 16.1 0.1 0.051 14.6 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 EMT54071.1 - 0.046 13.5 0.0 0.21 11.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain SIMPL PF04402.14 EMT54072.1 - 2.5e-40 139.1 4.0 2.8e-40 138.9 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Biopterin_H PF00351.21 EMT54072.1 - 0.0048 16.0 0.1 0.0083 15.2 0.0 1.3 1 1 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase DUF21 PF01595.20 EMT54073.1 - 3e-51 173.6 1.5 5.2e-51 172.8 1.5 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 EMT54073.1 - 1.7e-12 47.2 0.2 7.6e-12 45.1 0.0 2.2 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 EMT54073.1 - 2.4e-12 47.1 5.7 7.7e-07 29.5 0.3 2.5 2 0 0 2 2 2 2 CBS domain Thioredoxin_8 PF13905.6 EMT54073.1 - 0.00035 20.8 0.1 0.00071 19.9 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like MutL_C PF08676.11 EMT54074.1 - 1.6e-43 148.0 0.4 3e-43 147.1 0.4 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EMT54074.1 - 6.3e-35 119.4 0.0 1.1e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EMT54074.1 - 3.2e-11 43.2 0.0 5.9e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EMT54074.1 - 3.7e-07 30.6 0.0 1.2e-06 29.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mlh1_C PF16413.5 EMT54074.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus MutS_V PF00488.21 EMT54075.1 - 1.3e-85 286.2 0.4 2.4e-85 285.3 0.4 1.5 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 EMT54075.1 - 7.7e-48 161.4 0.0 2.4e-47 159.9 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 EMT54075.1 - 2e-45 155.3 1.4 2e-45 155.3 1.4 1.6 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EMT54075.1 - 1.1e-29 102.6 0.3 2.4e-29 101.5 0.3 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EMT54075.1 - 6.5e-09 36.2 0.0 8.9e-07 29.3 0.0 2.6 1 1 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 EMT54075.1 - 0.0047 16.6 0.0 0.028 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EMT54075.1 - 0.0065 16.5 0.0 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EMT54075.1 - 0.0075 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 EMT54075.1 - 0.013 15.2 0.0 0.042 13.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT54075.1 - 0.032 14.5 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMT54075.1 - 0.05 13.3 0.3 0.11 12.2 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EMT54075.1 - 0.057 13.9 0.1 0.36 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain TatD_DNase PF01026.21 EMT54075.1 - 0.081 12.3 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 TatD related DNase AAA_28 PF13521.6 EMT54075.1 - 0.093 13.0 0.8 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain COOH-NH2_lig PF14395.6 EMT54076.1 - 7.9e-90 300.5 0.0 1.1e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 Phage phiEco32-like COOH.NH2 ligase-type 2 CotE PF10628.9 EMT54077.1 - 3.7e-61 205.8 0.1 4.3e-61 205.6 0.1 1.0 1 0 0 1 1 1 1 Outer spore coat protein E (CotE) zf-TFIIIC PF12660.7 EMT54077.1 - 0.055 13.4 0.4 0.091 12.7 0.2 1.6 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex Com_YlbF PF06133.11 EMT54078.1 - 5.5e-25 88.0 8.0 6.4e-25 87.8 8.0 1.0 1 0 0 1 1 1 1 Control of competence regulator ComK, YlbF/YmcA Phage_sheath_1C PF17482.2 EMT54078.1 - 0.01 15.8 0.3 0.015 15.3 0.3 1.2 1 0 0 1 1 1 0 Phage tail sheath C-terminal domain BST2 PF16716.5 EMT54078.1 - 0.015 15.9 1.4 0.024 15.2 1.4 1.3 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF5600 PF18150.1 EMT54078.1 - 0.026 15.1 1.4 0.048 14.3 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5600) DUF1706 PF08020.11 EMT54078.1 - 0.052 13.5 1.2 0.2 11.6 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1706) ZnuA PF01297.17 EMT54078.1 - 0.09 12.2 0.9 0.1 12.0 0.9 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Enkurin PF13864.6 EMT54078.1 - 0.16 12.4 4.1 0.35 11.3 3.6 1.9 1 1 0 1 1 1 0 Calmodulin-binding TRAM PF01938.20 EMT54079.1 - 1.5e-07 31.2 0.0 1.7e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 EMT54079.1 - 0.024 14.8 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 TRAM domain Radical_SAM PF04055.21 EMT54080.1 - 2e-36 125.9 0.3 4e-36 124.9 0.3 1.6 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 EMT54080.1 - 4.9e-31 106.7 0.2 1.1e-30 105.6 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 SLH PF00395.20 EMT54082.1 - 2e-30 104.5 6.8 1.1e-18 67.0 0.1 4.0 3 1 0 3 3 3 3 S-layer homology domain BPL_LplA_LipB PF03099.19 EMT54083.1 - 2.5e-05 24.2 0.0 3.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Acyl_transf_3 PF01757.22 EMT54084.1 - 4.2e-21 75.4 50.7 4.8e-21 75.2 50.7 1.0 1 0 0 1 1 1 1 Acyltransferase family DUF4516 PF14990.6 EMT54084.1 - 4.4 7.1 5.4 0.51 10.1 0.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) CBS PF00571.28 EMT54086.1 - 1.1e-08 35.4 0.1 0.00018 21.9 0.0 2.2 2 0 0 2 2 2 2 CBS domain ATPgrasp_YheCD PF14398.6 EMT54087.1 - 5e-73 245.5 0.1 6.6e-73 245.1 0.1 1.1 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EMT54087.1 - 1.5e-09 37.6 0.0 0.0011 18.3 0.0 2.4 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 EMT54087.1 - 0.0016 17.8 0.1 0.017 14.5 0.0 2.4 2 1 0 2 2 2 1 Prokaryotic glutathione synthetase, ATP-grasp domain TTL PF03133.15 EMT54087.1 - 0.0037 16.4 0.0 0.018 14.2 0.0 1.8 1 1 1 2 2 2 1 Tubulin-tyrosine ligase family RimK PF08443.11 EMT54087.1 - 0.019 14.6 0.0 0.078 12.6 0.0 2.1 1 1 0 1 1 1 0 RimK-like ATP-grasp domain rRNA_methylase PF06962.12 EMT54088.1 - 1.5e-49 167.5 0.1 1.8e-49 167.2 0.1 1.1 1 0 0 1 1 1 1 Putative rRNA methylase Methyltransf_25 PF13649.6 EMT54088.1 - 3.7e-10 40.4 0.0 7.3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT54088.1 - 2.8e-09 36.7 0.0 4.6e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EMT54088.1 - 1.6e-08 34.5 0.0 2.4e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EMT54088.1 - 0.0002 20.6 0.0 0.00049 19.3 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 EMT54088.1 - 0.00022 21.1 0.2 0.00041 20.2 0.2 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_5 PF01795.19 EMT54088.1 - 0.00032 20.3 0.0 0.0016 18.0 0.0 1.8 2 0 0 2 2 2 1 MraW methylase family PrmA PF06325.13 EMT54088.1 - 0.0014 18.1 0.0 0.0019 17.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltr_RsmB-F PF01189.17 EMT54088.1 - 0.0018 17.9 0.0 0.0052 16.4 0.0 1.6 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Met_10 PF02475.16 EMT54088.1 - 0.0026 17.6 0.0 0.0029 17.4 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_32 PF13679.6 EMT54088.1 - 0.0036 17.3 0.0 0.0039 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT54088.1 - 0.0052 17.4 0.0 0.021 15.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EMT54088.1 - 0.0079 17.2 0.0 0.016 16.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EMT54088.1 - 0.011 15.5 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 EMT54088.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EMT54088.1 - 0.029 15.1 0.0 0.084 13.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EMT54088.1 - 0.034 14.3 0.0 0.12 12.5 0.0 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase GCD14 PF08704.10 EMT54088.1 - 0.043 13.5 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_15 PF09445.10 EMT54088.1 - 0.078 12.5 0.0 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Lactamase_B_2 PF12706.7 EMT54089.1 - 1.6e-23 83.3 0.1 2e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMT54089.1 - 1.9e-10 41.1 0.7 2.2e-10 40.9 0.7 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EMT54089.1 - 0.031 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain UPF0175 PF03683.13 EMT54089.1 - 0.14 11.9 0.2 0.29 10.8 0.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0175) NDUF_B12 PF08122.12 EMT54090.1 - 0.31 11.1 1.4 10 6.3 0.1 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family TPP_enzyme_C PF02775.21 EMT54091.1 - 2.2e-33 115.2 1.1 3.1e-31 108.3 0.4 2.1 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 EMT54091.1 - 2e-20 72.7 0.5 3.2e-20 72.0 0.5 1.3 1 0 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal TRAPP PF04051.16 EMT54091.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component POR_N PF01855.19 EMT54092.1 - 1.1e-63 215.1 0.2 1.9e-63 214.3 0.2 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 EMT54092.1 - 3.5e-42 144.5 0.2 9.2e-42 143.1 0.0 1.8 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 EMT54092.1 - 6.1e-13 49.0 0.1 1.4e-12 47.8 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 EMT54092.1 - 2.3e-07 30.8 0.2 4.9e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_N PF02776.18 EMT54092.1 - 8.4e-07 28.7 0.2 1.8e-06 27.7 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Spore_YhcN_YlaJ PF09580.10 EMT54092.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Peptidase_M19 PF01244.21 EMT54093.1 - 8.5e-101 337.3 0.0 9.5e-101 337.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 EMT54093.1 - 0.0027 17.5 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase SpoVS PF04232.12 EMT54094.1 - 4.3e-40 135.3 1.9 4.7e-40 135.2 1.9 1.0 1 0 0 1 1 1 1 Stage V sporulation protein S (SpoVS) YmdB PF13277.6 EMT54095.1 - 1.7e-111 371.6 0.0 1.9e-111 371.4 0.0 1.0 1 0 0 1 1 1 1 YmdB-like protein Metallophos PF00149.28 EMT54095.1 - 9.9e-08 32.7 0.0 1.3e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Polysacc_deac_1 PF01522.21 EMT54095.1 - 0.019 14.8 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide deacetylase DUF3552 PF12072.8 EMT54096.1 - 3.4e-71 238.8 36.1 3.4e-71 238.8 36.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3552) HD PF01966.22 EMT54096.1 - 8.1e-18 64.8 4.7 8.1e-18 64.8 4.7 2.6 2 1 0 2 2 2 1 HD domain KH_1 PF00013.29 EMT54096.1 - 1.4e-07 31.3 0.1 6.4e-07 29.1 0.1 2.3 1 0 0 1 1 1 1 KH domain HDOD PF08668.12 EMT54096.1 - 1.3e-05 24.8 5.0 0.00014 21.4 0.4 3.5 3 1 0 3 3 3 1 HDOD domain KH_4 PF13083.6 EMT54096.1 - 0.00015 21.6 0.1 0.00015 21.6 0.1 3.3 3 1 1 4 4 4 1 KH domain KH_2 PF07650.17 EMT54096.1 - 0.029 14.2 0.5 0.029 14.2 0.5 4.1 5 1 1 6 6 6 0 KH domain YdiH PF15930.5 EMT54096.1 - 0.042 14.0 0.3 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function Spore_YhcN_YlaJ PF09580.10 EMT54096.1 - 0.18 11.9 0.0 0.18 11.9 0.0 2.5 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF2937 PF11157.8 EMT54096.1 - 1.1 9.0 4.8 2.7 7.7 1.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) Spc7 PF08317.11 EMT54096.1 - 3.6 6.4 27.3 2.9 6.7 25.1 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein RecX PF02631.16 EMT54097.1 - 1.4e-32 112.8 2.3 3.2e-31 108.3 1.8 1.6 1 1 1 2 2 2 2 RecX family RecA PF00154.21 EMT54098.1 - 1e-145 484.1 4.9 1.2e-145 483.8 4.9 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 EMT54098.1 - 1.1e-10 41.2 0.2 7.1e-10 38.6 0.2 1.9 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 EMT54098.1 - 1.6e-07 30.9 0.6 2e-06 27.3 0.6 2.5 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 EMT54098.1 - 1.2e-05 25.3 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EMT54098.1 - 1.6e-05 24.8 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMT54098.1 - 0.00058 19.5 0.2 0.027 14.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT54098.1 - 0.0052 17.2 0.1 0.0095 16.3 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain CobU PF02283.16 EMT54098.1 - 0.0094 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA PF00004.29 EMT54098.1 - 0.013 16.0 0.1 0.022 15.2 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EMT54098.1 - 0.026 15.0 0.0 0.12 12.9 0.0 2.1 2 1 1 3 3 3 0 ABC transporter PT-HINT PF07591.11 EMT54098.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Pretoxin HINT domain AAA_35 PF14516.6 EMT54098.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DEAD PF00270.29 EMT54099.1 - 1.3e-52 178.1 0.0 2.7e-52 177.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMT54099.1 - 7.8e-33 113.1 0.1 2e-31 108.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DbpA PF03880.15 EMT54099.1 - 1.8e-24 85.5 0.1 7.4e-24 83.5 0.0 2.1 3 0 0 3 3 3 1 DbpA RNA binding domain ResIII PF04851.15 EMT54099.1 - 0.00019 21.5 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMT54099.1 - 0.0038 17.0 0.1 0.0095 15.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain RelE PF06296.12 EMT54099.1 - 0.0044 17.1 0.2 0.0087 16.2 0.2 1.4 1 0 0 1 1 1 1 RelE toxin of RelE / RelB toxin-antitoxin system CMS1 PF14617.6 EMT54099.1 - 0.0056 16.1 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 EMT54099.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Helicase Tropomyosin_1 PF12718.7 EMT54099.1 - 0.018 15.2 0.6 0.034 14.3 0.6 1.3 1 0 0 1 1 1 0 Tropomyosin like MgtE_N PF03448.17 EMT54099.1 - 0.031 14.9 2.4 1.8 9.2 0.1 2.7 2 0 0 2 2 2 0 MgtE intracellular N domain UTP25 PF06862.12 EMT54099.1 - 0.044 12.5 0.0 2.7 6.6 0.0 2.9 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CinA PF02464.17 EMT54100.1 - 3.4e-51 172.8 0.3 6.8e-51 171.9 0.3 1.5 1 0 0 1 1 1 1 Competence-damaged protein MoCF_biosynth PF00994.24 EMT54100.1 - 4.7e-35 120.4 0.2 2.4e-34 118.1 0.0 2.0 2 0 0 2 2 2 1 Probable molybdopterin binding domain CinA_KH PF18146.1 EMT54100.1 - 8.3e-30 102.8 1.6 2.4e-29 101.3 0.3 2.4 3 0 0 3 3 3 1 Damage-inducible protein CinA KH domain Cyclotide PF03784.13 EMT54100.1 - 0.11 12.5 1.2 0.22 11.6 1.2 1.4 1 0 0 1 1 1 0 Cyclotide family CDP-OH_P_transf PF01066.21 EMT54101.1 - 1.5e-16 60.9 1.1 1.5e-16 60.9 1.1 2.5 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UPF0004 PF00919.20 EMT54102.1 - 8e-30 102.8 0.2 1.4e-29 102.0 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 EMT54102.1 - 9.2e-27 94.4 0.1 2.1e-26 93.3 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily TRAM_2 PF18693.1 EMT54102.1 - 1.3e-20 73.3 1.4 1.3e-20 73.3 1.4 2.3 2 0 0 2 2 2 1 TRAM domain TRAM PF01938.20 EMT54102.1 - 2.7e-08 33.7 0.6 5.8e-08 32.6 0.6 1.6 1 0 0 1 1 1 1 TRAM domain TraT PF05818.12 EMT54102.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein HTH_25 PF13413.6 EMT54103.1 - 1.6e-22 79.1 0.1 2.9e-22 78.3 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EMT54103.1 - 5.9e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4115 PF13464.6 EMT54103.1 - 1e-06 28.8 0.2 2.6e-06 27.5 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4115) HTH_31 PF13560.6 EMT54103.1 - 1.8e-06 28.2 0.1 8.8e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 EMT54103.1 - 0.00012 22.0 0.1 0.0003 20.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix DUF3388 PF11868.8 EMT54104.1 - 3e-89 297.4 0.3 4.4e-89 296.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) ACT PF01842.25 EMT54104.1 - 2.5e-06 27.1 0.1 9.2e-06 25.3 0.1 2.0 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 EMT54104.1 - 0.011 16.3 0.1 0.035 14.7 0.1 1.9 1 1 0 1 1 1 0 ACT domain Secretin_N PF03958.17 EMT54104.1 - 0.097 13.1 0.3 0.19 12.1 0.3 1.4 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain DUF3243 PF11588.8 EMT54105.1 - 7.1e-35 119.2 1.6 8.1e-35 119.0 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3243) ParD PF09386.10 EMT54105.1 - 0.003 17.9 0.2 0.11 12.8 0.0 2.1 2 0 0 2 2 2 1 Antitoxin ParD adh_short_C2 PF13561.6 EMT54106.1 - 2.3e-47 161.5 0.0 2.7e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT54106.1 - 1.2e-43 148.8 0.0 1.5e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT54106.1 - 3.7e-09 36.8 0.0 4.9e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMT54106.1 - 0.00066 19.2 0.0 0.00082 18.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EMT54106.1 - 0.0017 17.8 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Glyco_trans_4_4 PF13579.6 EMT54106.1 - 0.012 16.1 0.2 7.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Polysacc_synt_2 PF02719.15 EMT54106.1 - 0.031 13.4 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_M16_C PF05193.21 EMT54107.1 - 1.5e-21 77.2 0.0 1.3e-18 67.6 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EMT54107.1 - 9.5e-20 71.1 0.3 2.1e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EMT54108.1 - 2.4e-22 79.8 0.2 1.5e-21 77.3 0.1 2.1 2 1 0 2 2 2 1 Peptidase M16 inactive domain BET PF17035.5 EMT54108.1 - 0.89 9.8 3.6 8 6.7 0.1 2.8 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation ABC_tran PF00005.27 EMT54109.1 - 4.1e-35 121.3 0.1 7.3e-35 120.5 0.1 1.4 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EMT54109.1 - 8.9e-16 58.6 0.1 1.7e-08 34.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMT54109.1 - 5.6e-05 23.7 0.0 8.7e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EMT54109.1 - 9.8e-05 21.9 0.4 0.0099 15.3 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMT54109.1 - 0.00019 21.1 0.0 0.00038 20.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMT54109.1 - 0.00063 19.7 0.1 0.0011 19.0 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EMT54109.1 - 0.00074 19.3 1.3 0.0048 16.6 1.3 2.1 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 EMT54109.1 - 0.0011 19.1 0.6 0.0081 16.4 0.1 2.5 1 1 1 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EMT54109.1 - 0.0012 18.7 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EMT54109.1 - 0.004 17.2 0.1 0.01 15.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TsaE PF02367.17 EMT54109.1 - 0.0053 16.8 0.3 0.014 15.4 0.3 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EMT54109.1 - 0.0088 16.0 0.1 0.5 10.3 0.1 2.2 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 EMT54109.1 - 0.01 16.1 0.6 0.039 14.2 0.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EMT54109.1 - 0.012 14.3 0.0 0.03 13.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EMT54109.1 - 0.016 15.1 1.8 0.025 14.5 0.1 2.1 2 1 1 3 3 3 0 NACHT domain AAA_27 PF13514.6 EMT54109.1 - 0.037 13.6 0.4 0.082 12.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EMT54109.1 - 0.045 12.9 0.1 0.079 12.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_ATPase PF09818.9 EMT54109.1 - 0.055 12.3 0.3 0.16 10.7 0.3 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_16 PF13191.6 EMT54109.1 - 0.066 13.6 1.3 0.19 12.1 1.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 EMT54109.1 - 0.067 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 EMT54109.1 - 0.07 13.5 2.1 0.94 9.8 2.1 2.3 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 EMT54109.1 - 0.072 13.0 0.4 0.23 11.4 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B BCA_ABC_TP_C PF12399.8 EMT54109.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Mg_chelatase PF01078.21 EMT54109.1 - 0.13 11.7 0.3 0.22 10.8 0.3 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EMT54109.1 - 0.14 11.7 2.1 0.23 11.0 0.2 2.2 3 1 0 3 3 3 0 AAA domain cobW PF02492.19 EMT54109.1 - 0.2 11.2 0.4 0.41 10.2 0.2 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain BPD_transp_2 PF02653.16 EMT54110.1 - 6.3e-35 120.6 38.6 9.3e-35 120.1 38.6 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 EMT54110.1 - 1.3e-29 103.5 0.0 1.7e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 EMT54110.1 - 1.2e-10 41.1 0.0 3.2e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_29 PF13555.6 EMT54110.1 - 0.00093 18.9 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EMT54110.1 - 0.0024 17.7 2.4 0.33 10.7 0.7 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT54110.1 - 0.0024 17.3 0.4 0.12 11.8 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EMT54110.1 - 0.0034 17.1 0.1 0.027 14.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMT54110.1 - 0.03 14.0 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EMT54110.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 EMT54110.1 - 0.13 12.7 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMT54110.1 - 0.27 11.1 0.0 0.45 10.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain BPD_transp_2 PF02653.16 EMT54111.1 - 1.1e-38 133.0 46.4 1.2e-38 132.8 46.4 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component FecCD PF01032.18 EMT54111.1 - 0.14 11.1 34.5 0.43 9.5 34.5 1.8 1 1 0 1 1 1 0 FecCD transport family Peripla_BP_6 PF13458.6 EMT54112.1 - 7.9e-62 209.9 6.0 9.2e-62 209.7 6.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 EMT54112.1 - 7.2e-19 68.1 0.1 9.1e-19 67.8 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 EMT54112.1 - 5.4e-16 58.5 3.7 1.5e-15 57.0 3.7 1.6 1 1 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_4 PF13407.6 EMT54112.1 - 0.041 13.5 6.7 0.12 11.9 3.8 2.5 2 1 0 2 2 2 0 Periplasmic binding protein domain Clp_N PF02861.20 EMT54112.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component adh_short PF00106.25 EMT54113.1 - 4.9e-58 195.8 1.9 6.1e-58 195.5 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMT54113.1 - 3.1e-56 190.6 2.5 4.4e-56 190.0 2.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMT54113.1 - 3.2e-10 40.2 1.0 5e-10 39.6 1.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMT54113.1 - 0.0037 16.7 0.0 0.011 15.1 0.0 1.6 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 EMT54113.1 - 0.011 15.7 0.5 0.018 14.9 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 EMT54113.1 - 0.011 15.6 1.1 0.036 13.9 1.1 1.8 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_10 PF13460.6 EMT54113.1 - 0.066 13.1 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMT54113.1 - 0.16 11.4 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sigma54_activat PF00158.26 EMT54114.1 - 7.8e-71 237.2 0.0 1.3e-70 236.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT54114.1 - 1.9e-20 73.4 0.0 6.7e-20 71.6 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain PAS PF00989.25 EMT54114.1 - 4.1e-18 65.4 0.0 9.4e-08 32.1 0.0 3.0 3 0 0 3 3 3 2 PAS fold HTH_8 PF02954.19 EMT54114.1 - 3.4e-15 55.5 0.6 1.1e-14 53.9 0.6 2.0 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family PAS_9 PF13426.7 EMT54114.1 - 4.5e-15 55.8 0.1 4.8e-06 26.8 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 EMT54114.1 - 3.1e-13 49.4 0.1 2.7e-05 24.1 0.0 3.3 3 0 0 3 3 2 2 PAS domain PAS_4 PF08448.10 EMT54114.1 - 1.2e-11 44.8 0.0 8.1e-05 22.8 0.0 3.6 4 0 0 4 4 3 2 PAS fold PAS_7 PF12860.7 EMT54114.1 - 1.2e-06 28.7 0.0 0.019 15.1 0.0 3.1 3 0 0 3 3 3 2 PAS fold Mg_chelatase PF01078.21 EMT54114.1 - 1.6e-06 27.6 0.1 0.00024 20.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 EMT54114.1 - 2.4e-05 24.8 0.0 5.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 EMT54114.1 - 3.9e-05 23.5 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMT54114.1 - 5.6e-05 23.2 0.0 0.0002 21.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_30 PF13556.6 EMT54114.1 - 0.00041 20.1 0.4 0.001 18.8 0.4 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain AAA_16 PF13191.6 EMT54114.1 - 0.0015 18.9 0.1 0.007 16.8 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EMT54114.1 - 0.0036 17.1 0.0 0.015 15.1 0.0 2.0 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EMT54114.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HTH_17 PF12728.7 EMT54114.1 - 0.02 15.1 0.0 0.064 13.5 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 EMT54114.1 - 0.029 14.2 0.2 0.079 12.8 0.2 1.7 1 0 0 1 1 1 0 Homeodomain-like domain PAS_10 PF13596.6 EMT54114.1 - 0.033 14.8 0.0 2.9 8.5 0.0 2.6 2 0 0 2 2 2 0 PAS domain AAA_7 PF12775.7 EMT54114.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SPAN PF02510.14 EMT54114.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Surface presentation of antigens protein Cu_amine_oxidN1 PF07833.11 EMT54115.1 - 3e-26 91.7 0.0 9.5e-26 90.1 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase N-terminal domain Peptidase_M23 PF01551.22 EMT54115.1 - 1.5e-21 76.4 0.0 4.8e-21 74.8 0.0 1.9 1 0 0 1 1 1 1 Peptidase family M23 LysM PF01476.20 EMT54115.1 - 3.6e-06 27.0 0.0 9.5e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 LysM domain BPD_transp_2 PF02653.16 EMT54116.1 - 9e-42 143.1 31.9 1.1e-41 142.9 31.9 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF5337 PF17272.2 EMT54116.1 - 1.5 8.7 5.7 0.26 11.1 1.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5337) BPD_transp_2 PF02653.16 EMT54117.1 - 8.9e-46 156.2 32.2 8.9e-46 156.2 32.2 2.0 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 EMT54118.1 - 3.1e-50 170.3 0.2 1e-30 107.0 0.1 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMT54118.1 - 1.3e-07 31.7 0.9 0.011 15.5 0.1 2.6 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EMT54118.1 - 9.2e-05 22.4 0.4 0.0032 17.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EMT54118.1 - 0.00072 19.3 0.1 0.0067 16.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EMT54118.1 - 0.0056 16.8 0.5 0.16 12.1 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EMT54118.1 - 0.0067 17.0 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMT54118.1 - 0.0078 16.0 4.6 1.3 8.6 0.1 2.2 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EMT54118.1 - 0.023 14.2 1.7 0.21 11.0 1.7 2.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EMT54118.1 - 0.023 14.4 0.1 0.12 12.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EMT54118.1 - 0.025 14.6 0.5 0.071 13.2 0.5 1.8 1 1 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 EMT54118.1 - 0.028 14.7 0.2 0.17 12.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EMT54118.1 - 0.046 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bmp PF02608.14 EMT54119.1 - 1.5e-83 280.3 5.7 1.7e-83 280.1 5.7 1.0 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Peripla_BP_4 PF13407.6 EMT54119.1 - 9.1e-07 28.7 2.8 2.1e-06 27.5 2.8 1.5 1 1 0 1 1 1 1 Periplasmic binding protein domain UTRA PF07702.13 EMT54120.1 - 2.3e-32 111.7 0.1 4.3e-31 107.7 0.0 2.0 2 0 0 2 2 2 1 UTRA domain GntR PF00392.21 EMT54120.1 - 1.3e-22 79.2 0.2 2.8e-22 78.1 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 EMT54120.1 - 1.2e-05 24.8 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 EMT54120.1 - 0.00027 20.6 0.1 0.00057 19.6 0.1 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EMT54120.1 - 0.0031 17.4 0.1 0.0066 16.4 0.1 1.5 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 EMT54120.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 EMT54120.1 - 0.0091 15.5 0.3 0.015 14.8 0.3 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 EMT54120.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain RP-C PF03428.13 EMT54120.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_10 PF04967.12 EMT54120.1 - 0.017 14.9 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_IclR PF09339.10 EMT54120.1 - 0.054 13.3 0.1 0.098 12.5 0.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_5 PF01022.20 EMT54120.1 - 0.057 13.3 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 EMT54120.1 - 0.071 13.3 0.0 0.18 12.0 0.0 1.7 2 0 0 2 2 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 EMT54120.1 - 0.082 12.8 0.2 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 EMT54120.1 - 0.085 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain RepL PF05732.11 EMT54120.1 - 0.088 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) TrmB PF01978.19 EMT54120.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 EMT54120.1 - 0.1 12.5 0.1 0.29 11.1 0.1 1.7 2 0 0 2 2 2 0 MarR family FtsK_SpoIIIE PF01580.18 EMT54121.1 - 3.1e-69 233.0 1.2 7.3e-50 169.6 0.0 2.5 1 1 1 2 2 2 2 FtsK/SpoIIIE family FtsK_alpha PF17854.1 EMT54121.1 - 3.1e-32 110.7 0.1 3.1e-32 110.7 0.1 1.9 2 0 0 2 2 2 1 FtsK alpha domain FtsK_gamma PF09397.10 EMT54121.1 - 9.9e-29 98.9 1.7 1.7e-28 98.2 0.1 2.2 2 0 0 2 2 2 1 Ftsk gamma domain FtsK_4TM PF13491.6 EMT54121.1 - 1.2e-06 28.3 14.7 0.00084 19.1 3.6 2.2 2 0 0 2 2 2 2 4TM region of DNA translocase FtsK/SpoIIIE AAA_10 PF12846.7 EMT54121.1 - 7.1e-05 21.9 0.0 0.0013 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.17 EMT54121.1 - 0.0053 16.9 0.8 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 EMT54121.1 - 0.0069 15.5 0.0 0.017 14.2 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AIG1 PF04548.16 EMT54121.1 - 0.045 13.1 0.5 2.3 7.5 0.0 2.9 3 0 0 3 3 3 0 AIG1 family AAA_22 PF13401.6 EMT54121.1 - 0.064 13.5 0.0 0.27 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EMT54121.1 - 0.068 13.2 0.0 0.51 10.3 0.0 2.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Ribosomal_S25 PF03297.15 EMT54121.1 - 0.072 13.3 2.7 0.13 12.5 0.0 2.4 2 0 0 2 2 2 0 S25 ribosomal protein betaPIX_CC PF16523.5 EMT54121.1 - 0.1 12.4 2.6 0.3 10.9 2.6 1.7 1 0 0 1 1 1 0 betaPIX coiled coil TrwB_AAD_bind PF10412.9 EMT54121.1 - 0.11 11.4 0.0 0.11 11.4 0.0 2.2 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.9 EMT54121.1 - 0.31 10.2 2.9 0.45 9.7 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) TrbC PF04956.13 EMT54121.1 - 3.4 8.0 9.6 0.49 10.6 2.7 2.5 2 0 0 2 2 2 0 TrbC/VIRB2 family YlzJ PF14035.6 EMT54122.1 - 9.4e-21 73.8 0.3 1.1e-20 73.6 0.3 1.0 1 0 0 1 1 1 1 YlzJ-like protein CLP_protease PF00574.23 EMT54123.1 - 6.1e-38 130.5 0.3 8.1e-38 130.1 0.3 1.1 1 0 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.18 EMT54123.1 - 0.0038 17.2 0.5 0.068 13.1 0.0 2.4 2 1 0 2 2 2 1 Peptidase family S49 ECH_1 PF00378.20 EMT54123.1 - 0.062 12.6 0.2 0.88 8.8 0.1 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase CLP1_P PF16575.5 EMT54123.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Phage_Gp23 PF10669.9 EMT54124.1 - 0.15 12.4 1.4 0.68 10.3 0.0 2.5 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) RNase_J_C PF17770.1 EMT54125.1 - 2.7e-30 105.2 0.1 5.2e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease J C-terminal domain Lactamase_B PF00753.27 EMT54125.1 - 1e-16 61.6 0.1 1e-16 61.6 0.1 2.1 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EMT54125.1 - 1.5e-12 47.3 0.4 3.9e-10 39.5 0.0 2.8 3 0 0 3 3 3 2 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EMT54125.1 - 4.9e-12 45.8 0.1 1.8e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EMT54125.1 - 0.036 13.5 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain GerA PF03323.13 EMT54126.1 - 3e-180 599.7 0.2 3.4e-180 599.5 0.2 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein Spore_permease PF03845.13 EMT54127.1 - 1.3e-53 181.9 29.6 1.6e-53 181.6 29.6 1.1 1 0 0 1 1 1 1 Spore germination protein Spore_GerAC PF05504.11 EMT54128.1 - 2.8e-29 102.5 0.0 4.3e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal PIRT PF15099.6 EMT54129.1 - 0.021 14.4 0.3 0.023 14.3 0.3 1.0 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF1129 PF06570.11 EMT54129.1 - 0.12 11.9 0.9 0.13 11.8 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DHDPS PF00701.22 EMT54130.1 - 4.7e-100 334.0 0.1 5.2e-100 333.9 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CutC PF03932.14 EMT54130.1 - 0.0037 16.8 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 CutC family Peripla_BP_1 PF00532.21 EMT54130.1 - 0.083 12.3 0.0 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family PcrB PF01884.17 EMT54130.1 - 0.13 11.7 0.0 0.47 9.9 0.0 1.8 2 0 0 2 2 2 0 PcrB family AA_kinase PF00696.28 EMT54131.1 - 5.1e-48 163.8 0.7 8.4e-48 163.1 0.7 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 EMT54131.1 - 3.3e-22 78.1 0.7 2.6e-21 75.2 0.1 2.8 3 0 0 3 3 3 1 ACT domain ACT PF01842.25 EMT54131.1 - 0.0017 18.1 0.2 1.2 8.9 0.0 2.9 2 1 0 2 2 2 2 ACT domain DUF2007 PF09413.10 EMT54131.1 - 0.11 12.7 1.5 43 4.4 0.1 3.9 4 0 0 4 4 4 0 Putative prokaryotic signal transducing protein Semialdhyde_dhC PF02774.18 EMT54132.1 - 3.4e-58 196.7 0.0 5e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EMT54132.1 - 1.1e-34 119.5 0.1 2.1e-34 118.6 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 EMT54132.1 - 0.015 14.8 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Gp_dh_C PF02800.20 EMT54132.1 - 0.018 14.6 0.1 0.058 13.0 0.1 1.8 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DapB_N PF01113.20 EMT54132.1 - 0.025 14.7 0.5 0.078 13.1 0.2 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 EMT54132.1 - 0.044 13.9 0.1 0.099 12.7 0.1 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain S4 PF01479.25 EMT54132.1 - 0.064 13.0 0.2 0.51 10.1 0.0 2.5 3 0 0 3 3 3 0 S4 domain DXP_reductoisom PF02670.16 EMT54132.1 - 0.098 13.4 0.1 0.24 12.1 0.1 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Flavoprotein PF02441.19 EMT54133.1 - 1.5e-15 57.3 0.2 1.9e-15 56.9 0.2 1.2 1 0 0 1 1 1 1 Flavoprotein DpaA_N PF16924.5 EMT54134.1 - 5.7e-32 110.2 0.2 4.2e-31 107.4 0.1 2.2 2 1 0 2 2 2 1 Dipicolinate synthase subunit A N-terminal domain AlaDh_PNT_C PF01262.21 EMT54134.1 - 7.3e-08 32.0 0.0 2.2e-07 30.4 0.0 1.9 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EMT54134.1 - 1.2e-06 28.0 0.1 2.4e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMT54134.1 - 9.3e-06 25.7 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 EMT54134.1 - 1.4e-05 25.2 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 EMT54134.1 - 2.1e-05 24.7 0.0 4.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 EMT54134.1 - 2.2e-05 24.8 0.0 0.002 18.5 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding IlvN PF07991.12 EMT54134.1 - 0.0001 21.9 0.0 0.00044 19.9 0.0 2.0 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox PF00070.27 EMT54134.1 - 0.0026 18.3 0.1 0.027 15.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sulfotransfer_4 PF17784.1 EMT54134.1 - 0.0038 17.1 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain F420_oxidored PF03807.17 EMT54134.1 - 0.0051 17.4 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh PF00389.30 EMT54134.1 - 0.051 13.2 0.0 0.32 10.7 0.0 2.2 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain THF_DHG_CYH_C PF02882.19 EMT54134.1 - 0.057 12.7 0.2 0.32 10.3 0.2 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox_2 PF07992.14 EMT54134.1 - 0.061 12.5 0.1 0.092 12.0 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMT54134.1 - 0.1 12.8 0.0 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 EMT54134.1 - 0.19 11.7 0.3 2.7 8.0 0.1 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PRC PF05239.16 EMT54135.1 - 3.7e-16 59.0 1.1 4e-16 58.9 1.1 1.0 1 0 0 1 1 1 1 PRC-barrel domain Peptidase_M16 PF00675.20 EMT54136.1 - 2.6e-43 147.5 0.0 2.4e-42 144.4 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EMT54136.1 - 1.5e-38 132.6 0.1 4.4e-38 131.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Cass2 PF14526.6 EMT54136.1 - 0.025 14.8 0.0 11 6.2 0.0 3.1 3 0 0 3 3 3 0 Integron-associated effector binding protein DUF3791 PF12668.7 EMT54136.1 - 0.11 12.6 0.1 2 8.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3791) Polysacc_deac_1 PF01522.21 EMT54137.1 - 2.4e-29 101.7 0.0 5.1e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EMT54137.1 - 0.00029 20.1 0.0 0.00037 19.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 EMT54137.1 - 0.00043 20.0 0.1 0.0014 18.3 0.1 1.9 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) PG_binding_4 PF12229.8 EMT54137.1 - 0.0013 19.0 0.4 0.19 12.0 0.6 3.3 3 1 1 4 4 4 1 Putative peptidoglycan binding domain RNase_PH PF01138.21 EMT54138.1 - 4e-44 150.3 0.0 5e-22 78.8 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EMT54138.1 - 1.4e-21 76.3 3.3 2.5e-12 46.7 0.3 2.8 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.23 EMT54138.1 - 1.6e-18 66.8 0.8 1.6e-18 66.8 0.8 2.5 4 0 0 4 4 4 1 S1 RNA binding domain PNPase PF03726.14 EMT54138.1 - 2e-18 66.7 7.6 2e-18 66.7 7.6 1.9 2 0 0 2 2 2 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_1 PF00013.29 EMT54138.1 - 2.4e-08 33.7 2.6 2.4e-08 33.7 2.6 3.1 3 0 0 3 3 3 1 KH domain ATP-grasp PF02222.22 EMT54138.1 - 0.05 13.2 0.2 0.55 9.8 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain KH_5 PF13184.6 EMT54138.1 - 0.05 13.7 3.9 0.2 11.8 1.0 2.7 2 0 0 2 2 2 0 NusA-like KH domain SPATA25 PF15218.6 EMT54138.1 - 0.17 11.6 0.3 0.33 10.7 0.3 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 Ribosomal_S15 PF00312.22 EMT54139.1 - 5.4e-38 129.1 2.0 6.1e-38 128.9 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 Rep_1 PF01446.17 EMT54139.1 - 0.0025 17.3 0.2 0.0031 17.1 0.2 1.0 1 0 0 1 1 1 1 Replication protein FAD_syn PF06574.12 EMT54140.1 - 6.1e-48 162.7 0.0 1.2e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 FAD synthetase Flavokinase PF01687.17 EMT54140.1 - 2.8e-40 137.1 0.2 4.9e-40 136.3 0.2 1.4 1 0 0 1 1 1 1 Riboflavin kinase CTP_transf_like PF01467.26 EMT54140.1 - 0.0052 17.0 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like Ribosomal_S22 PF08136.11 EMT54140.1 - 0.092 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 30S ribosomal protein subunit S22 family TruB_N PF01509.18 EMT54141.1 - 4.4e-59 199.1 0.1 5.9e-59 198.7 0.1 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EMT54141.1 - 6.5e-17 61.4 0.1 1.5e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain PseudoU_synth_2 PF00849.22 EMT54141.1 - 0.022 14.8 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA pseudouridylate synthase DKCLD PF08068.12 EMT54141.1 - 0.078 13.1 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 DKCLD (NUC011) domain DHH PF01368.20 EMT54142.1 - 4.2e-15 55.8 0.0 6.6e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 DHH family DHHA1 PF02272.19 EMT54142.1 - 7e-14 52.4 0.9 3.2e-13 50.3 0.7 2.2 2 1 0 2 2 2 1 DHHA1 domain RBFA PF02033.18 EMT54143.1 - 1.5e-33 115.4 0.1 1.7e-33 115.2 0.1 1.0 1 0 0 1 1 1 1 Ribosome-binding factor A DUF503 PF04456.12 EMT54144.1 - 2.7e-29 100.9 0.1 2.9e-29 100.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF503) DUF2987 PF11205.8 EMT54144.1 - 0.0066 16.4 0.0 0.0078 16.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2987) DUF1351 PF07083.11 EMT54144.1 - 0.056 13.2 0.1 0.067 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Aldo_ket_red PF00248.21 EMT54144.1 - 0.057 12.6 0.1 0.058 12.6 0.1 1.1 1 0 0 1 1 1 0 Aldo/keto reductase family FUR PF01475.19 EMT54144.1 - 0.13 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Ferric uptake regulator family IF-2 PF11987.8 EMT54145.1 - 2.1e-39 133.9 1.3 7.9e-39 132.0 1.3 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 EMT54145.1 - 3.5e-34 118.0 9.9 4e-34 117.9 3.6 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF2_N PF04760.15 EMT54145.1 - 1.7e-27 95.0 4.4 1.1e-15 57.2 0.1 2.5 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 EMT54145.1 - 2.7e-11 43.5 0.6 7.5e-11 42.1 0.6 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EMT54145.1 - 9.9e-07 28.4 0.2 4.4e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 EMT54145.1 - 3.9e-06 26.5 0.3 1.9e-05 24.3 0.3 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU_D2 PF03144.25 EMT54145.1 - 8.3e-06 26.1 1.6 0.095 13.1 0.3 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 PduV-EutP PF10662.9 EMT54145.1 - 1.7e-05 24.6 0.8 5.4e-05 23.0 0.3 2.2 2 0 0 2 2 1 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 EMT54145.1 - 2e-05 24.3 0.1 3.9e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 EMT54145.1 - 3.1e-05 23.9 0.1 0.019 14.9 0.1 2.7 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EMT54145.1 - 0.00012 21.6 0.5 0.00054 19.4 0.5 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF3791 PF12668.7 EMT54145.1 - 0.0043 17.1 0.3 0.051 13.6 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3791) MeaB PF03308.16 EMT54145.1 - 0.011 14.7 5.0 0.072 12.1 0.4 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EMT54145.1 - 0.015 15.5 0.1 0.03 14.6 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 EMT54145.1 - 0.052 13.6 0.1 0.052 13.6 0.1 3.1 4 0 0 4 4 3 0 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 EMT54145.1 - 0.069 12.9 0.0 0.24 11.1 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 EMT54145.1 - 0.07 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain EF-hand_10 PF14788.6 EMT54145.1 - 0.13 12.1 0.6 0.31 10.9 0.6 1.6 1 0 0 1 1 1 0 EF hand Ribosomal_L7Ae PF01248.26 EMT54146.1 - 5.8e-18 64.4 0.8 7.3e-18 64.1 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NPA PF16469.5 EMT54146.1 - 0.11 13.1 0.0 0.14 12.7 0.0 1.1 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF448 PF04296.13 EMT54147.1 - 8.6e-28 96.0 0.3 1e-27 95.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF448) Transglut_core2 PF13369.6 EMT54147.1 - 0.08 12.5 0.0 0.12 12.0 0.0 1.3 1 1 0 1 1 1 0 Transglutaminase-like superfamily DUF3648 PF12364.8 EMT54147.1 - 0.13 12.4 0.1 0.14 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) GARS_A PF01071.19 EMT54147.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NusA_N PF08529.11 EMT54148.1 - 3.3e-45 153.4 3.4 6.8e-45 152.3 3.4 1.6 1 0 0 1 1 1 1 NusA N-terminal domain KH_5 PF13184.6 EMT54148.1 - 1.3e-30 105.3 0.9 2.8e-29 101.0 0.2 2.5 2 0 0 2 2 2 1 NusA-like KH domain S1 PF00575.23 EMT54148.1 - 9.9e-07 29.0 1.6 2.5e-06 27.7 0.5 2.3 2 0 0 2 2 2 1 S1 RNA binding domain KH_2 PF07650.17 EMT54148.1 - 9.5e-05 22.2 1.9 0.0041 16.9 0.0 3.9 4 0 0 4 4 4 1 KH domain KH_1 PF00013.29 EMT54148.1 - 0.00064 19.5 0.0 0.31 10.9 0.0 2.7 2 0 0 2 2 2 2 KH domain DUF150 PF02576.17 EMT54149.1 - 6.7e-29 100.1 0.2 1.2e-28 99.3 0.1 1.5 2 0 0 2 2 2 1 RimP N-terminal domain DUF150_C PF17384.2 EMT54149.1 - 9.5e-14 51.3 2.4 9.9e-14 51.2 0.9 1.7 2 0 0 2 2 2 1 RimP C-terminal SH3 domain DNA_pol3_alpha PF07733.12 EMT54150.1 - 1.4e-62 211.7 0.0 8.7e-45 153.3 0.0 2.5 1 1 1 2 2 2 2 Bacterial DNA polymerase III alpha NTPase domain PHP PF02811.19 EMT54150.1 - 2.4e-51 174.3 0.1 5.1e-51 173.3 0.1 1.6 1 0 0 1 1 1 1 PHP domain RNase_T PF00929.24 EMT54150.1 - 3.2e-38 131.9 0.0 9.8e-38 130.3 0.0 1.9 1 0 0 1 1 1 1 Exonuclease DNA_pol3_finger PF17657.1 EMT54150.1 - 2.3e-28 98.7 0.1 7.8e-28 96.9 0.0 2.0 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha subunit finger domain DNA_pol3_a_NI PF14480.6 EMT54150.1 - 9.9e-17 60.7 0.2 2.3e-16 59.5 0.2 1.7 1 0 0 1 1 1 1 DNA polymerase III polC-type N-terminus I HHH_6 PF14579.6 EMT54150.1 - 2e-09 37.6 0.0 7.4e-09 35.8 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif DNA_pol3_a_NII PF11490.8 EMT54150.1 - 4.4e-08 33.0 4.5 5.3e-08 32.8 2.8 2.1 2 0 0 2 2 2 1 DNA polymerase III polC-type N-terminus II tRNA_anti-codon PF01336.25 EMT54150.1 - 1.2e-07 31.6 0.3 2.9e-07 30.4 0.3 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RNase_H_2 PF13482.6 EMT54150.1 - 3.9e-05 23.7 0.4 0.00028 20.9 0.0 2.6 2 1 0 2 2 2 1 RNase_H superfamily HHH_3 PF12836.7 EMT54150.1 - 0.00011 22.4 0.1 0.00074 19.7 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif DNA_pol_A_exo1 PF01612.20 EMT54150.1 - 0.0018 18.0 0.1 0.038 13.7 0.1 3.2 3 1 0 3 3 3 1 3'-5' exonuclease zf-ribbon_3 PF13248.6 EMT54150.1 - 0.002 17.5 2.1 0.27 10.7 0.3 2.4 2 0 0 2 2 2 2 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EMT54150.1 - 0.0026 17.8 1.2 0.0062 16.6 1.2 1.7 1 0 0 1 1 1 1 Zinc ribbon domain YhfH PF14149.6 EMT54150.1 - 0.09 12.8 0.3 0.29 11.1 0.3 1.9 1 0 0 1 1 1 0 YhfH-like protein TF_Zn_Ribbon PF08271.12 EMT54150.1 - 0.33 10.5 1.7 1.6 8.3 1.7 2.2 1 1 0 1 1 1 0 TFIIB zinc-binding Rubredoxin PF00301.20 EMT54150.1 - 5.4 7.1 6.4 2.3 8.3 0.2 2.7 3 0 0 3 3 2 0 Rubredoxin tRNA-synt_2b PF00587.25 EMT54151.1 - 1.4e-52 178.3 0.0 5.3e-52 176.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 EMT54151.1 - 3.3e-27 95.0 0.3 5.8e-27 94.2 0.3 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 EMT54151.1 - 3.7e-20 71.9 0.6 8.8e-20 70.7 0.6 1.7 1 0 0 1 1 1 1 Anticodon binding domain GcpE PF04551.14 EMT54152.1 - 3.4e-140 467.1 3.3 3.9e-140 466.9 3.3 1.0 1 0 0 1 1 1 1 GcpE protein DUF1107 PF06526.12 EMT54152.1 - 0.036 14.0 0.3 0.093 12.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1107) CCG PF02754.16 EMT54152.1 - 0.15 12.3 0.0 0.88 9.8 0.0 2.3 2 0 0 2 2 2 0 Cysteine-rich domain Peptidase_M50 PF02163.22 EMT54153.1 - 1.7e-75 253.6 2.8 4.2e-75 252.2 2.8 1.6 1 1 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 EMT54153.1 - 2.7e-09 36.7 0.4 6.1e-09 35.6 0.4 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EMT54153.1 - 4.7e-08 33.2 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EMT54153.1 - 1.7e-06 28.3 0.1 3.5e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EMT54153.1 - 0.028 14.7 0.1 0.049 14.0 0.1 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 EMT54153.1 - 0.06 13.3 0.6 0.2 11.7 0.2 2.0 2 0 0 2 2 2 0 Tricorn protease PDZ domain DXP_reductoisom PF02670.16 EMT54154.1 - 1.3e-45 155.3 3.5 2.1e-45 154.6 3.5 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 EMT54154.1 - 1.7e-43 147.6 0.0 3.1e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 EMT54154.1 - 2.4e-43 146.2 0.0 6.8e-43 144.7 0.0 1.8 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Sacchrp_dh_NADP PF03435.18 EMT54154.1 - 0.037 14.3 0.2 0.12 12.7 0.1 1.9 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain CTP_transf_1 PF01148.20 EMT54155.1 - 1.7e-66 224.7 16.9 1.9e-66 224.6 16.9 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family Prenyltransf PF01255.19 EMT54156.1 - 1.1e-84 283.5 0.0 1.2e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase VbhA PF18495.1 EMT54156.1 - 0.065 13.1 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 Antitoxin VbhA RRF PF01765.19 EMT54157.1 - 6.7e-70 234.2 3.5 8.3e-70 233.9 3.5 1.1 1 0 0 1 1 1 1 Ribosome recycling factor DUF883 PF05957.13 EMT54157.1 - 0.082 13.5 3.9 0.14 12.8 1.6 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4168 PF13767.6 EMT54157.1 - 1.3 10.2 6.3 2.2 9.5 4.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) AA_kinase PF00696.28 EMT54158.1 - 9.7e-29 100.7 0.7 1.1e-28 100.4 0.7 1.0 1 0 0 1 1 1 1 Amino acid kinase family EF_TS PF00889.19 EMT54159.1 - 2.1e-73 246.4 0.5 2.8e-73 245.9 0.5 1.2 1 0 0 1 1 1 1 Elongation factor TS UBA PF00627.31 EMT54159.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain HOIP-UBA PF16678.5 EMT54159.1 - 0.14 12.2 1.3 0.35 10.9 0.1 2.1 3 0 0 3 3 3 0 HOIP UBA domain pair Ribosomal_S2 PF00318.20 EMT54160.1 - 4.2e-101 336.7 0.0 4.7e-101 336.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 LUD_dom PF02589.15 EMT54160.1 - 0.077 12.7 0.1 0.75 9.5 0.1 2.2 1 1 1 2 2 2 0 LUD domain PucR PF07905.11 EMT54160.1 - 0.093 13.0 0.1 2.9 8.2 0.0 2.4 2 1 0 2 2 2 0 Purine catabolism regulatory protein-like family YceG PF02618.16 EMT54161.1 - 0.00063 19.4 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 YceG-like family DUF2802 PF10975.8 EMT54162.1 - 1.5e-06 28.2 0.9 1.5e-06 28.2 0.9 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2802) Sigma70_r4_2 PF08281.12 EMT54162.1 - 0.0011 18.6 1.3 0.002 17.8 0.1 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sec2p PF06428.11 EMT54162.1 - 0.0014 18.6 2.3 0.002 18.0 2.3 1.4 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p DUF2730 PF10805.8 EMT54162.1 - 0.0023 18.0 0.2 0.0078 16.3 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2730) Kre28 PF17097.5 EMT54162.1 - 0.0086 15.1 0.1 0.0098 14.9 0.1 1.0 1 0 0 1 1 1 1 Spindle pole body component TMEM51 PF15345.6 EMT54162.1 - 0.012 15.5 0.5 0.022 14.6 0.1 1.5 1 1 0 1 1 1 0 Transmembrane protein 51 APC_N_CC PF16689.5 EMT54162.1 - 0.012 15.6 0.3 0.026 14.6 0.3 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain CMD PF02627.20 EMT54162.1 - 0.024 14.7 0.5 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family SRC-1 PF08832.10 EMT54162.1 - 0.038 15.0 0.0 0.055 14.5 0.0 1.3 1 0 0 1 1 1 0 Steroid receptor coactivator Peptidase_S49_N PF08496.10 EMT54162.1 - 0.06 13.4 1.6 0.21 11.7 1.6 1.8 1 1 0 1 1 1 0 Peptidase family S49 N-terminal CCDC-167 PF15188.6 EMT54162.1 - 0.064 13.6 1.5 0.13 12.6 1.5 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Gram_pos_anchor PF00746.21 EMT54162.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Cnn_1N PF07989.11 EMT54162.1 - 0.16 12.1 3.4 0.26 11.5 3.4 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 EMT54162.1 - 0.22 12.1 8.8 0.3 11.6 8.8 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF5446 PF17522.2 EMT54162.1 - 0.56 10.4 4.1 7.4 6.8 1.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5446) Menin PF05053.13 EMT54163.1 - 0.046 12.1 2.4 0.051 11.9 2.4 1.0 1 0 0 1 1 1 0 Menin Porph_ging PF09697.10 EMT54163.1 - 0.16 12.5 1.2 0.24 12.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) BRF1 PF07741.13 EMT54163.1 - 0.29 11.5 8.0 0.36 11.2 8.0 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DDHD PF02862.17 EMT54163.1 - 0.37 10.9 4.4 0.42 10.8 4.4 1.0 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 EMT54163.1 - 1.5 6.7 4.5 1.5 6.7 4.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 EMT54163.1 - 1.9 7.8 7.4 2.1 7.6 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TERB2 PF15101.6 EMT54163.1 - 3.8 7.5 7.3 4.5 7.3 7.3 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Sperm_Ag_HE2 PF05324.13 EMT54163.1 - 4.5 7.8 5.3 8 7.0 0.9 2.5 2 1 1 3 3 3 0 Sperm antigen HE2 HAUS6_N PF14661.6 EMT54163.1 - 9.2 5.8 10.0 10 5.6 10.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FapA PF03961.13 EMT54164.1 - 5.1e-120 401.2 16.7 5.7e-120 401.0 16.7 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A MinC_C PF03775.16 EMT54164.1 - 0.00071 19.5 9.4 0.003 17.5 1.8 3.2 1 1 0 2 2 2 2 Septum formation inhibitor MinC, C-terminal domain Sigma70_r2 PF04542.14 EMT54165.1 - 9.7e-17 60.5 0.0 1.9e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EMT54165.1 - 2.9e-16 58.7 0.1 1.3e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EMT54165.1 - 2.8e-09 36.5 0.2 3.4e-08 33.0 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 EMT54165.1 - 2.2e-07 30.9 2.0 9.1e-06 25.7 0.5 2.7 2 1 1 3 3 3 1 Sigma-70 region 3 UPF0122 PF04297.14 EMT54165.1 - 0.0032 17.7 0.1 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_ECF PF07638.11 EMT54165.1 - 0.017 15.0 0.2 0.048 13.6 0.1 1.8 2 0 0 2 2 2 0 ECF sigma factor HTH_5 PF01022.20 EMT54165.1 - 0.063 13.2 0.2 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 EMT54165.1 - 0.065 13.0 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain MarR_2 PF12802.7 EMT54165.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_Mga PF08280.11 EMT54165.1 - 0.15 12.1 0.1 15 5.7 0.0 2.4 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain CheD PF03975.13 EMT54167.1 - 1.8e-35 121.3 0.2 2.4e-35 120.9 0.2 1.2 1 0 0 1 1 1 1 CheD chemotactic sensory transduction Asp_protease_2 PF13650.6 EMT54167.1 - 0.062 13.9 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease CheC PF04509.12 EMT54168.1 - 3.8e-27 93.9 0.1 4e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 CheC-like family CheX PF13690.6 EMT54168.1 - 5.9e-12 45.6 0.0 3.6e-07 30.3 0.0 2.5 3 0 0 3 3 3 2 Chemotaxis phosphatase CheX CheW PF01584.19 EMT54169.1 - 7.9e-36 122.7 1.8 8.9e-36 122.6 1.8 1.0 1 0 0 1 1 1 1 CheW-like domain P2 PF07194.11 EMT54170.1 - 7.3e-30 102.9 1.5 3.4e-29 100.7 1.5 2.3 1 0 0 1 1 1 1 P2 response regulator binding domain CheW PF01584.19 EMT54170.1 - 1.1e-26 93.1 1.1 1.1e-26 93.1 1.1 1.7 2 0 0 2 2 2 1 CheW-like domain Hpt PF01627.23 EMT54170.1 - 2.1e-18 66.4 3.4 2.4e-18 66.2 0.0 2.7 3 0 0 3 3 3 1 Hpt domain HATPase_c PF02518.26 EMT54170.1 - 2.2e-17 63.6 0.2 6.4e-17 62.1 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 EMT54170.1 - 8.2e-17 61.4 2.0 3e-16 59.5 2.0 2.1 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain HATPase_c_3 PF13589.6 EMT54170.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CheB_methylest PF01339.17 EMT54171.1 - 1e-59 201.1 0.1 7.7e-59 198.2 0.0 2.1 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 EMT54171.1 - 1.5e-23 83.1 0.2 3.4e-23 82.0 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain DXP_reductoisom PF02670.16 EMT54171.1 - 0.011 16.4 0.2 0.048 14.4 0.0 2.1 3 0 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Abhydrolase_3 PF07859.13 EMT54171.1 - 0.086 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold ParA PF10609.9 EMT54172.1 - 9.1e-17 61.3 0.7 1.1e-15 57.7 0.7 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EMT54172.1 - 3.7e-14 52.9 0.0 5e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EMT54172.1 - 4.7e-12 46.2 0.0 6.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EMT54172.1 - 3e-05 23.6 0.0 0.0077 15.7 0.0 2.0 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 EMT54172.1 - 0.00026 20.3 0.3 0.00067 18.9 0.1 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EMT54172.1 - 0.00095 18.7 0.1 0.0056 16.2 0.1 2.0 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 EMT54172.1 - 0.013 14.8 0.1 0.031 13.6 0.1 1.8 1 1 0 1 1 1 0 ATPase MipZ AAA_24 PF13479.6 EMT54172.1 - 0.034 13.9 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.11 EMT54172.1 - 0.043 13.1 0.4 2.5 7.4 0.1 2.1 2 0 0 2 2 2 0 VirC1 protein MeaB PF03308.16 EMT54172.1 - 0.059 12.3 0.0 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TrwB_AAD_bind PF10412.9 EMT54172.1 - 0.11 11.4 0.1 0.25 10.2 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 EMT54173.1 - 2.2e-41 141.7 0.0 3.8e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 EMT54173.1 - 0.00085 19.4 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 EMT54173.1 - 0.002 18.2 0.0 0.0051 16.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.23 EMT54173.1 - 0.0023 18.0 0.0 0.013 15.6 0.0 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 EMT54173.1 - 0.0031 17.8 0.5 0.096 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EMT54173.1 - 0.0051 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EMT54173.1 - 0.0061 16.5 0.2 0.023 14.6 0.1 1.9 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.6 EMT54173.1 - 0.012 15.7 0.2 0.35 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EMT54173.1 - 0.017 15.6 0.0 0.04 14.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT54173.1 - 0.021 15.2 1.0 0.11 12.9 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EMT54173.1 - 0.029 14.7 0.1 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.6 EMT54173.1 - 0.03 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMT54173.1 - 0.03 13.9 0.1 0.42 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 EMT54173.1 - 0.046 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein RecX PF02631.16 EMT54173.1 - 0.05 14.0 0.2 0.12 12.8 0.2 1.7 1 0 0 1 1 1 0 RecX family RNA_helicase PF00910.22 EMT54173.1 - 0.08 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EMT54173.1 - 0.086 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EMT54173.1 - 0.094 12.6 0.0 0.34 10.8 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase AAA_34 PF13872.6 EMT54173.1 - 0.095 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 ATPase_2 PF01637.18 EMT54173.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EMT54173.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EMT54173.1 - 0.26 11.8 0.0 0.26 11.8 0.0 2.2 2 1 0 2 2 1 0 AAA domain FHIPEP PF00771.20 EMT54174.1 - 7.5e-278 923.5 10.9 8.5e-278 923.3 10.9 1.0 1 0 0 1 1 1 1 FHIPEP family Bac_export_2 PF01312.19 EMT54175.1 - 2.4e-131 437.9 9.6 2.7e-131 437.7 9.6 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family DUF202 PF02656.15 EMT54175.1 - 0.74 10.3 5.9 1.8 9.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) TRIQK PF15168.6 EMT54175.1 - 0.83 9.6 7.4 1.6 8.7 0.0 3.6 4 0 0 4 4 4 0 Triple QxxK/R motif-containing protein family Bac_export_1 PF01311.20 EMT54176.1 - 1.9e-70 237.0 32.3 2.2e-70 236.8 32.3 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 Bac_export_3 PF01313.19 EMT54177.1 - 1.3e-28 98.7 12.7 1.5e-28 98.5 12.7 1.1 1 0 0 1 1 1 1 Bacterial export proteins, family 3 DUF4282 PF14110.6 EMT54177.1 - 0.00023 21.8 5.8 0.00031 21.4 5.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) FtsX PF02687.21 EMT54177.1 - 2 8.9 9.6 5.4 7.6 9.6 1.6 1 1 0 1 1 1 0 FtsX-like permease family FliP PF00813.20 EMT54178.1 - 2.1e-81 272.4 22.1 3.3e-81 271.7 22.1 1.3 1 0 0 1 1 1 1 FliP family FliO PF04347.13 EMT54179.1 - 1e-11 45.0 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Flagellar biosynthesis protein, FliO Response_reg PF00072.24 EMT54180.1 - 9.6e-35 119.1 1.6 1.1e-34 119.0 1.6 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HydF_dimer PF18128.1 EMT54180.1 - 0.058 13.5 0.1 2.9 8.0 0.0 2.1 1 1 1 2 2 2 0 Hydrogen maturase F dimerization domain DUF2179 PF10035.9 EMT54180.1 - 0.15 11.8 0.5 1 9.2 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2179) CheC PF04509.12 EMT54181.1 - 1.5e-29 101.6 5.5 1.1e-15 57.2 0.1 2.5 2 0 0 2 2 2 2 CheC-like family FliMN_C PF01052.20 EMT54181.1 - 3e-24 84.8 2.3 5.4e-24 84.0 2.3 1.4 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term CheX PF13690.6 EMT54181.1 - 5.8e-08 32.8 2.2 0.011 15.9 0.7 2.5 2 0 0 2 2 2 2 Chemotaxis phosphatase CheX FliM PF02154.15 EMT54181.1 - 9.1e-06 25.7 0.2 1.7e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 Flagellar motor switch protein FliM PRCC PF10253.9 EMT54181.1 - 5.1 7.8 10.5 6.7 7.4 9.4 1.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting FliM PF02154.15 EMT54182.1 - 1.9e-72 243.2 0.2 2.6e-72 242.8 0.2 1.2 1 0 0 1 1 1 1 Flagellar motor switch protein FliM FliMN_C PF01052.20 EMT54182.1 - 1.6e-22 79.3 1.0 2.8e-22 78.5 1.0 1.5 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliL PF03748.14 EMT54183.1 - 4.7e-11 43.2 0.7 6.7e-11 42.7 0.7 1.2 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL TPR_21 PF09976.9 EMT54183.1 - 0.0022 17.7 0.1 0.0029 17.3 0.1 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat-like domain DUF1712 PF08217.11 EMT54183.1 - 0.016 13.7 0.2 0.018 13.5 0.2 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) DUF4083 PF13314.6 EMT54183.1 - 0.019 14.9 1.2 0.7 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) MPS-4 PF17523.2 EMT54183.1 - 0.038 14.1 0.2 0.065 13.4 0.2 1.4 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 FlbD PF06289.11 EMT54184.1 - 1.4e-28 98.2 0.1 1.6e-28 98.1 0.1 1.0 1 0 0 1 1 1 1 Flagellar and Swarming motility proteins Flg_bbr_C PF06429.13 EMT54185.1 - 3.7e-23 81.5 0.4 1.1e-22 79.9 0.2 2.0 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 EMT54185.1 - 1.1e-11 44.4 0.1 1.1e-11 44.4 0.1 3.1 3 0 0 3 3 3 1 Flagella basal body rod protein Flagellar_put PF12611.8 EMT54186.1 - 1e-11 44.4 1.9 1.9e-11 43.5 1.9 1.5 1 0 0 1 1 1 1 Putative flagellar DUF4258 PF14076.6 EMT54186.1 - 0.0044 17.4 0.2 0.016 15.6 0.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4258) Flg_hook PF02120.16 EMT54187.1 - 1.4e-18 66.6 3.3 1.4e-18 66.6 3.3 2.8 2 1 0 2 2 2 1 Flagellar hook-length control protein FliK mTERF PF02536.14 EMT54187.1 - 0.014 14.4 0.2 0.022 13.7 0.2 1.2 1 0 0 1 1 1 0 mTERF DUF4191 PF13829.6 EMT54187.1 - 0.039 13.3 0.4 0.085 12.2 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) Glutaminase PF04960.15 EMT54187.1 - 0.052 12.7 3.5 0.094 11.9 3.3 1.5 1 1 0 1 1 1 0 Glutaminase MgtE_N PF03448.17 EMT54188.1 - 8.5e-13 48.8 9.7 5.2e-08 33.4 2.4 3.4 2 2 0 3 3 3 2 MgtE intracellular N domain FliG_M PF14841.6 EMT54188.1 - 7.3e-05 22.9 7.2 1.8 8.8 0.1 4.6 2 2 2 4 4 4 2 FliG middle domain ThrE PF06738.12 EMT54188.1 - 0.019 14.3 0.6 0.057 12.8 0.0 1.9 2 0 0 2 2 2 0 Putative threonine/serine exporter Fez1 PF06818.15 EMT54188.1 - 0.021 15.3 15.9 0.033 14.6 15.9 1.3 1 0 0 1 1 1 0 Fez1 UPF0242 PF06785.11 EMT54188.1 - 0.026 14.6 5.6 0.026 14.6 5.6 3.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MscS_porin PF12795.7 EMT54188.1 - 0.028 14.0 22.8 0.023 14.2 16.1 2.5 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain DUF2383 PF09537.10 EMT54188.1 - 0.052 13.9 11.9 1.7 9.0 5.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF2383) Pox_A32 PF04665.12 EMT54188.1 - 0.055 12.9 0.7 0.11 12.0 0.3 1.6 1 1 0 1 1 1 0 Poxvirus A32 protein LMBR1 PF04791.16 EMT54188.1 - 0.096 11.6 0.9 0.12 11.2 0.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Njmu-R1 PF15053.6 EMT54188.1 - 0.12 11.5 3.8 0.19 10.8 3.3 1.5 1 1 1 2 2 2 0 Mjmu-R1-like protein family SlyX PF04102.12 EMT54188.1 - 0.15 12.7 16.9 1.2 9.8 0.1 3.0 2 1 1 3 3 3 0 SlyX DUF4795 PF16043.5 EMT54188.1 - 0.23 11.0 23.3 1.2 8.7 23.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4094 PF13334.6 EMT54188.1 - 0.25 11.8 6.3 0.35 11.3 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF4988 PF16378.5 EMT54188.1 - 0.28 10.8 6.1 0.44 10.2 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function Spc7 PF08317.11 EMT54188.1 - 0.51 9.2 23.9 0.13 11.2 12.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EMT54188.1 - 0.62 10.1 21.7 2 8.5 0.1 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3106 PF11304.8 EMT54188.1 - 0.63 10.5 9.1 0.57 10.7 4.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) Lebercilin PF15619.6 EMT54188.1 - 0.74 9.4 20.3 0.79 9.4 14.9 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 EMT54188.1 - 0.93 9.7 21.7 3 8.0 6.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MPS2 PF17060.5 EMT54188.1 - 0.95 8.7 12.4 2.1 7.5 7.7 2.0 1 1 1 2 2 2 0 Monopolar spindle protein 2 Striatin PF08232.12 EMT54188.1 - 1.2 9.8 18.8 1.7 9.2 15.3 2.2 1 1 1 2 2 2 0 Striatin family Tropomyosin_1 PF12718.7 EMT54188.1 - 1.5 9.0 21.9 2.2 8.4 10.8 2.3 2 0 0 2 2 2 0 Tropomyosin like APG6_N PF17675.1 EMT54188.1 - 1.6 9.3 23.0 0.92 10.0 15.9 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-Q PF13094.6 EMT54188.1 - 2 8.6 18.8 0.21 11.8 14.2 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Med4 PF10018.9 EMT54188.1 - 2.2 7.9 15.3 0.19 11.4 9.4 2.0 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4763 PF15960.5 EMT54188.1 - 2.7 7.2 14.1 0.39 10.0 5.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) bZIP_1 PF00170.21 EMT54188.1 - 2.9 8.1 11.5 20 5.4 2.1 3.4 2 1 1 3 3 3 0 bZIP transcription factor Csm1_N PF18504.1 EMT54188.1 - 3.5 8.0 21.5 0.35 11.2 0.4 3.7 3 1 1 4 4 3 0 Csm1 N-terminal domain FlaC_arch PF05377.11 EMT54188.1 - 4.2 7.8 6.4 3.4 8.1 2.9 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Mod_r PF07200.13 EMT54188.1 - 5.3 7.1 20.3 7.6 6.6 13.7 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FlxA PF14282.6 EMT54188.1 - 6.1 6.9 29.7 2 8.5 0.3 2.8 2 1 0 2 2 2 0 FlxA-like protein TolA_bind_tri PF16331.5 EMT54188.1 - 7 6.8 16.1 26 5.0 13.2 2.9 2 1 0 2 2 2 0 TolA binding protein trimerisation NPV_P10 PF05531.12 EMT54188.1 - 7.2 7.2 17.0 1.7 9.1 2.7 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein FliJ PF02050.16 EMT54189.1 - 5.2e-14 52.5 12.4 6.7e-14 52.2 12.4 1.1 1 0 0 1 1 1 1 Flagellar FliJ protein YscO-like PF16789.5 EMT54189.1 - 4.8e-12 46.2 13.1 2.9e-08 33.9 6.1 2.1 2 0 0 2 2 2 2 YscO-like protein PH_13 PF16652.5 EMT54189.1 - 0.0014 18.4 0.4 0.0022 17.8 0.4 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain DUF974 PF06159.13 EMT54189.1 - 0.085 12.7 3.1 0.1 12.4 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF974) ATP-synt_ab PF00006.25 EMT54190.1 - 4.6e-78 261.7 0.3 6.2e-78 261.3 0.3 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 EMT54190.1 - 2.5e-25 88.1 0.2 4e-25 87.5 0.2 1.3 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATP-synt_ab_N PF02874.23 EMT54190.1 - 2.2e-07 31.3 0.5 2.2e-07 31.3 0.5 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ABC_tran PF00005.27 EMT54190.1 - 0.00067 20.2 0.1 0.0013 19.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EMT54190.1 - 0.013 15.4 0.4 0.032 14.1 0.2 1.7 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 EMT54190.1 - 0.022 14.9 0.6 0.04 14.0 0.6 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain NYN_YacP PF05991.11 EMT54190.1 - 0.18 11.7 0.1 1.1 9.2 0.0 1.9 2 0 0 2 2 2 0 YacP-like NYN domain FliH PF02108.16 EMT54191.1 - 2.8e-20 72.7 0.2 2.8e-20 72.7 0.2 1.9 2 1 0 2 2 2 1 Flagellar assembly protein FliH NolV PF06635.12 EMT54191.1 - 0.00011 21.6 2.8 0.00011 21.6 2.8 1.8 1 1 1 2 2 2 1 Nodulation protein NolV DivIVA PF05103.13 EMT54191.1 - 0.052 13.6 15.6 0.13 12.4 5.7 3.1 1 1 2 3 3 3 0 DivIVA protein Yae1_N PF09811.9 EMT54191.1 - 0.069 12.9 1.0 0.15 11.7 1.0 1.6 1 0 0 1 1 1 0 Essential protein Yae1, N terminal ATP-synt_B PF00430.18 EMT54191.1 - 0.09 12.9 21.5 0.24 11.5 14.8 2.7 1 1 0 2 2 2 0 ATP synthase B/B' CF(0) Ada_Zn_binding PF02805.16 EMT54191.1 - 0.16 12.1 0.0 14 5.8 0.1 2.5 2 0 0 2 2 2 0 Metal binding domain of Ada Ribosomal_L22 PF00237.19 EMT54191.1 - 0.56 10.5 3.4 20 5.5 0.7 2.4 1 1 1 2 2 2 0 Ribosomal protein L22p/L17e V-ATPase_G_2 PF16999.5 EMT54191.1 - 4 7.9 23.4 22 5.5 1.4 3.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit FliG_N PF14842.6 EMT54192.1 - 1.1e-47 160.8 16.8 3.2e-37 127.2 2.0 3.4 2 1 0 3 3 3 2 FliG N-terminal domain FliG_C PF01706.16 EMT54192.1 - 2.6e-47 159.5 19.2 9.2e-44 148.1 8.0 3.2 3 0 0 3 3 3 2 FliG C-terminal domain FliG_M PF14841.6 EMT54192.1 - 8.2e-37 125.3 14.4 4e-32 110.3 3.4 4.0 3 1 1 4 4 4 2 FliG middle domain MgtE_N PF03448.17 EMT54192.1 - 6e-08 33.2 15.7 0.0031 18.1 0.3 4.9 1 1 4 5 5 5 5 MgtE intracellular N domain His_biosynth PF00977.21 EMT54192.1 - 0.0023 17.4 2.5 0.0027 17.2 1.0 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein TFA2_Winged_2 PF18121.1 EMT54192.1 - 0.051 13.3 0.1 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 TRAF_BIRC3_bd PF16673.5 EMT54192.1 - 3.7 7.4 15.7 0.84 9.5 0.9 4.2 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain YscJ_FliF PF01514.17 EMT54193.1 - 2.3e-51 174.2 0.6 2.3e-51 174.2 0.6 2.4 3 0 0 3 3 3 1 Secretory protein of YscJ/FliF family YscJ_FliF_C PF08345.11 EMT54193.1 - 2e-17 63.9 1.1 1.3e-16 61.3 0.1 2.5 2 1 0 2 2 2 1 Flagellar M-ring protein C-terminal FliE PF02049.18 EMT54194.1 - 3e-30 104.2 6.4 3.5e-30 104.0 6.4 1.0 1 0 0 1 1 1 1 Flagellar hook-basal body complex protein FliE Flg_bbr_C PF06429.13 EMT54195.1 - 1.4e-13 50.8 0.2 2.9e-13 49.8 0.2 1.6 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 EMT54195.1 - 3.4e-09 36.4 6.3 6.1e-09 35.6 6.3 1.5 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bb_rod PF00460.20 EMT54196.1 - 1.1e-05 25.3 1.5 1.1e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Flagella basal body rod protein DUF928 PF06051.12 EMT54196.1 - 0.053 13.4 0.2 0.71 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) CodY PF06018.14 EMT54197.1 - 8.7e-76 253.3 0.1 1.1e-75 253.0 0.1 1.1 1 0 0 1 1 1 1 CodY GAF-like domain HTH_CodY PF08222.11 EMT54197.1 - 7.2e-37 124.8 1.1 1.4e-36 123.8 1.1 1.5 1 0 0 1 1 1 1 CodY helix-turn-helix domain HTH_11 PF08279.12 EMT54197.1 - 1.5e-05 24.8 0.4 7.5e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 HTH domain HTH_Crp_2 PF13545.6 EMT54197.1 - 2.1e-05 24.4 0.1 5.2e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 EMT54197.1 - 5.3e-05 23.0 0.1 0.00014 21.7 0.1 1.7 1 0 0 1 1 1 1 MarR family GntR PF00392.21 EMT54197.1 - 0.00032 20.3 0.4 0.001 18.7 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 EMT54197.1 - 0.00034 20.9 0.1 0.0015 18.8 0.1 2.0 2 0 0 2 2 2 1 Transcriptional regulator HTH_20 PF12840.7 EMT54197.1 - 0.00048 20.1 0.1 0.0015 18.5 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.22 EMT54197.1 - 0.00049 20.0 0.4 0.001 19.0 0.0 1.7 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 EMT54197.1 - 0.00094 19.0 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 EMT54197.1 - 0.0024 17.7 0.4 0.023 14.6 0.0 2.5 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 EMT54197.1 - 0.0027 17.2 0.1 0.0027 17.2 0.1 2.4 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_41 PF14502.6 EMT54197.1 - 0.0093 15.6 0.4 0.043 13.5 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Ribosomal_S25 PF03297.15 EMT54197.1 - 0.014 15.6 0.1 0.026 14.7 0.1 1.4 1 0 0 1 1 1 0 S25 ribosomal protein GAF PF01590.26 EMT54197.1 - 0.056 14.1 0.0 0.089 13.4 0.0 1.5 1 0 0 1 1 1 0 GAF domain HTH_46 PF15977.5 EMT54197.1 - 0.12 12.3 0.2 0.32 11.0 0.0 1.8 2 0 0 2 2 1 0 Winged helix-turn-helix DNA binding AAA_2 PF07724.14 EMT54198.1 - 9.4e-48 162.6 3.1 1.6e-39 135.8 0.4 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 EMT54198.1 - 4.1e-16 59.6 0.7 6.4e-07 29.9 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMT54198.1 - 9.4e-08 32.1 0.2 1.7e-05 24.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 EMT54198.1 - 5e-06 26.5 0.1 2.2e-05 24.4 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 EMT54198.1 - 8.4e-06 26.1 0.2 0.0028 17.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 EMT54198.1 - 1.6e-05 24.1 1.1 0.0011 18.2 0.0 2.9 3 0 0 3 3 3 1 MCM P-loop domain Mg_chelatase PF01078.21 EMT54198.1 - 0.00023 20.6 0.4 0.0075 15.7 0.0 3.2 3 1 1 4 4 4 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EMT54198.1 - 0.00035 20.4 0.2 0.0088 15.8 0.1 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EMT54198.1 - 0.00074 19.9 2.3 0.0064 16.9 0.3 2.8 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 EMT54198.1 - 0.0018 18.0 0.4 0.051 13.3 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 EMT54198.1 - 0.0019 18.7 0.0 0.0063 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain IPT PF01745.16 EMT54198.1 - 0.0068 15.8 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 EMT54198.1 - 0.0072 16.5 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EMT54198.1 - 0.0074 15.5 5.1 0.025 13.8 5.1 2.0 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 EMT54198.1 - 0.01 16.1 1.1 0.028 14.7 0.1 2.3 3 0 0 3 3 2 0 AAA domain TniB PF05621.11 EMT54198.1 - 0.011 15.1 1.1 0.028 13.8 0.1 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_lid_3 PF17862.1 EMT54198.1 - 0.012 15.4 0.1 0.054 13.3 0.1 2.2 1 0 0 1 1 1 0 AAA+ lid domain DALR_2 PF09190.11 EMT54198.1 - 0.015 15.8 0.7 0.035 14.6 0.0 1.9 2 0 0 2 2 1 0 DALR domain NTPase_1 PF03266.15 EMT54198.1 - 0.02 14.8 3.2 3.5 7.5 0.1 2.6 2 1 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 EMT54198.1 - 0.03 13.6 0.1 0.09 12.0 0.1 1.7 1 1 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EMT54198.1 - 0.044 13.7 1.4 2.9 7.8 0.0 3.3 3 0 0 3 3 3 0 NACHT domain TsaE PF02367.17 EMT54198.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EMT54198.1 - 0.054 13.2 0.2 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.29 EMT54198.1 - 0.058 13.2 1.9 0.75 9.5 0.3 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 EMT54198.1 - 0.065 12.7 0.1 0.19 11.2 0.0 1.9 2 0 0 2 2 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EMT54198.1 - 0.092 13.3 0.7 0.24 11.9 0.7 1.9 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 EMT54198.1 - 0.094 13.0 2.1 0.27 11.6 2.1 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EMT54198.1 - 0.11 12.3 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 EMT54198.1 - 0.45 10.9 7.1 1.3 9.4 0.4 3.1 3 1 0 3 3 3 0 AAA domain AAA_6 PF12774.7 EMT54198.1 - 0.65 8.9 2.8 1.8 7.4 0.1 2.2 1 1 1 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Proteasome PF00227.26 EMT54199.1 - 3.2e-23 82.2 0.1 5.2e-23 81.5 0.1 1.3 1 1 0 1 1 1 1 Proteasome subunit FtsQ PF03799.15 EMT54199.1 - 0.042 14.7 0.0 0.72 10.7 0.0 2.3 2 1 0 2 2 2 0 Cell division protein FtsQ Phage_integrase PF00589.22 EMT54200.1 - 4.9e-48 163.2 0.0 1.9e-47 161.3 0.0 1.9 3 0 0 3 3 3 1 Phage integrase family Phage_int_SAM_1 PF02899.17 EMT54200.1 - 2.1e-23 82.4 2.4 3.9e-23 81.6 0.6 2.3 2 1 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 EMT54200.1 - 3.6e-10 40.2 0.8 1.8e-09 37.9 0.1 2.4 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 EMT54200.1 - 1.4e-05 25.3 0.0 3.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Phage integrase SAM-like domain Phage_integr_3 PF16795.5 EMT54200.1 - 0.01 15.8 0.1 6 6.7 0.0 2.6 3 0 0 3 3 3 2 Archaeal phage integrase CbiJ PF02571.14 EMT54200.1 - 0.025 14.1 0.5 0.63 9.5 0.0 2.1 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK Acetyltransf_11 PF13720.6 EMT54200.1 - 0.13 12.7 0.4 1.1 9.7 0.1 2.6 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 HTH_23 PF13384.6 EMT54200.1 - 0.33 10.8 1.4 8.8 6.3 0.1 3.6 2 1 2 4 4 4 0 Homeodomain-like domain GIDA PF01134.22 EMT54201.1 - 6e-117 391.0 0.0 7.7e-117 390.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EMT54201.1 - 2e-05 24.7 0.0 6.8e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMT54201.1 - 2.3e-05 23.8 0.1 5.3e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EMT54201.1 - 0.00061 19.7 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 EMT54201.1 - 0.001 18.8 0.1 0.015 14.9 0.1 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMT54201.1 - 0.0019 17.5 0.9 0.0025 17.1 0.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EMT54201.1 - 0.0022 17.4 0.1 0.16 11.3 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMT54201.1 - 0.012 16.1 0.0 0.048 14.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMT54201.1 - 0.022 13.8 0.0 0.081 12.0 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 EMT54201.1 - 0.045 13.0 0.1 0.72 9.0 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase IU_nuc_hydro PF01156.19 EMT54201.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase HSV_VP16_C PF12149.8 EMT54201.1 - 0.1 12.7 0.0 0.63 10.2 0.0 2.1 2 0 0 2 2 2 0 Herpes simplex virus virion protein 16 C terminal HI0933_like PF03486.14 EMT54201.1 - 0.11 11.2 0.0 0.46 9.1 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Topoisom_bac PF01131.20 EMT54202.1 - 1.4e-136 455.8 1.3 2.1e-136 455.2 1.3 1.3 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EMT54202.1 - 5.1e-31 107.0 0.1 1.8e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 EMT54202.1 - 6.2e-31 105.9 19.5 2.4e-13 49.6 2.4 3.5 3 0 0 3 3 3 3 Topoisomerase DNA binding C4 zinc finger RNA_POL_M_15KD PF02150.16 EMT54202.1 - 2.7e-05 23.9 15.2 4.2e-05 23.3 1.8 3.0 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit Toprim_4 PF13662.6 EMT54202.1 - 0.00046 20.6 0.0 0.0017 18.7 0.0 2.1 1 1 0 1 1 1 1 Toprim domain DZR PF12773.7 EMT54202.1 - 0.018 15.1 4.9 2.5 8.2 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon Auto_anti-p27 PF06677.12 EMT54202.1 - 0.036 14.2 8.1 0.065 13.4 2.4 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_4 PF13717.6 EMT54202.1 - 7.5 6.6 8.0 65 3.6 0.1 3.0 2 1 0 2 2 2 0 zinc-ribbon domain DNA_processg_A PF02481.15 EMT54203.1 - 1.3e-78 263.1 0.0 1.8e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 DNA recombination-mediator protein A DprA_WH PF17782.1 EMT54203.1 - 7.5e-10 38.8 0.0 2e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 DprA winged helix domain LDcluster4 PF18306.1 EMT54203.1 - 0.0016 18.1 2.4 0.014 15.0 2.1 2.2 2 0 0 2 2 2 1 SLOG cluster4 family DHquinase_II PF01220.19 EMT54203.1 - 0.19 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Dehydroquinase class II CoA_binding PF02629.19 EMT54204.1 - 3.7e-26 91.6 9.1 1.4e-25 89.8 3.2 2.4 2 0 0 2 2 2 2 CoA binding domain Ligase_CoA PF00549.19 EMT54204.1 - 6.3e-17 61.8 0.7 6.3e-17 61.8 0.7 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 EMT54204.1 - 1.1e-10 41.5 0.0 1.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EMT54204.1 - 0.0002 21.9 0.1 0.00054 20.4 0.1 1.9 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 EMT54205.1 - 7.9e-82 273.7 7.9 7.9e-82 273.7 7.9 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EMT54205.1 - 1.1e-26 93.4 1.3 2.5e-26 92.3 1.3 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EMT54205.1 - 4.1e-18 65.6 3.5 9.3e-18 64.5 3.5 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EMT54205.1 - 1.3e-05 25.0 1.1 3.4e-05 23.7 1.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 EMT54205.1 - 0.096 12.3 1.8 0.16 11.5 1.8 1.5 1 1 0 1 1 1 0 ATP-grasp domain AlbA_2 PF04326.14 EMT54207.1 - 2.2e-17 63.5 0.5 3.3e-17 63.0 0.5 1.3 1 0 0 1 1 1 1 Putative DNA-binding domain SCP2 PF02036.17 EMT54208.1 - 4.5e-23 81.7 0.1 5.2e-23 81.5 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EMT54208.1 - 0.0013 19.1 0.0 0.0013 19.0 0.0 1.0 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal YbjQ_1 PF01906.17 EMT54209.1 - 4.5e-39 133.3 3.1 5e-39 133.1 3.1 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding DUF4156 PF13698.6 EMT54209.1 - 0.074 13.4 0.1 0.15 12.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4156) Hexapep_2 PF14602.6 EMT54209.1 - 0.91 9.3 0.0 0.91 9.3 0.0 2.7 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase ABC2_membrane_3 PF12698.7 EMT54210.1 - 4.8e-24 85.1 14.0 1.8e-14 53.6 10.0 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein DUF3533 PF12051.8 EMT54210.1 - 2.4e-09 36.6 14.6 1.2e-07 31.1 0.0 3.2 3 1 0 3 3 3 2 Protein of unknown function (DUF3533) ABC2_membrane PF01061.24 EMT54210.1 - 2.2e-08 33.8 13.5 4.3e-08 32.8 13.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter IFT57 PF10498.9 EMT54210.1 - 5.4e-05 22.3 7.8 0.0021 17.1 2.4 3.0 2 1 1 3 3 3 2 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 EMT54210.1 - 0.00014 21.9 2.4 0.00014 21.9 2.4 3.5 1 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein Flagellin_C PF00700.21 EMT54210.1 - 0.0036 17.6 2.0 0.0036 17.6 2.0 3.3 3 0 0 3 3 3 1 Bacterial flagellin C-terminal helical region DUF5082 PF16888.5 EMT54210.1 - 0.0038 17.5 10.2 4.4 7.6 0.0 4.1 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) Prominin PF05478.11 EMT54210.1 - 0.0042 15.1 6.6 0.012 13.6 1.0 2.3 1 1 1 2 2 2 1 Prominin Golgin_A5 PF09787.9 EMT54210.1 - 0.0055 16.2 7.4 0.0055 16.2 7.4 2.3 1 1 0 1 1 1 1 Golgin subfamily A member 5 AAA_13 PF13166.6 EMT54210.1 - 0.0057 15.4 7.5 0.0091 14.7 7.5 1.2 1 0 0 1 1 1 1 AAA domain WXG100 PF06013.12 EMT54210.1 - 0.0069 16.6 0.8 0.0069 16.6 0.8 5.9 3 3 3 7 7 5 1 Proteins of 100 residues with WXG YkyA PF10368.9 EMT54210.1 - 0.0079 15.9 5.5 0.081 12.6 3.6 2.5 1 1 1 2 2 2 1 Putative cell-wall binding lipoprotein ABC2_membrane_5 PF13346.6 EMT54210.1 - 0.0079 15.8 8.2 0.015 14.9 8.2 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein Nup88 PF10168.9 EMT54210.1 - 0.009 13.9 3.0 0.15 9.8 2.8 2.1 2 0 0 2 2 2 1 Nuclear pore component APG17 PF04108.12 EMT54210.1 - 0.013 14.7 9.7 0.022 13.9 9.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 FliJ PF02050.16 EMT54210.1 - 0.018 15.2 6.5 0.018 15.2 6.5 3.6 3 1 1 4 4 3 0 Flagellar FliJ protein UPF0449 PF15136.6 EMT54210.1 - 0.022 15.2 4.4 0.039 14.4 0.9 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Atg14 PF10186.9 EMT54210.1 - 0.024 13.8 16.2 0.17 10.9 7.9 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MIP-T3_C PF17749.1 EMT54210.1 - 0.043 13.8 5.5 1.2 9.1 0.1 2.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region NPV_P10 PF05531.12 EMT54210.1 - 0.058 13.9 14.6 1.3 9.6 0.3 4.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF677 PF05055.12 EMT54210.1 - 0.064 12.1 0.4 0.15 10.9 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF677) ApoLp-III PF07464.11 EMT54210.1 - 0.069 13.3 14.1 0.91 9.6 3.2 4.4 2 1 3 5 5 4 0 Apolipophorin-III precursor (apoLp-III) EzrA PF06160.12 EMT54210.1 - 0.09 10.9 4.0 1.8 6.7 2.2 2.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 EMT54210.1 - 0.095 12.2 15.0 1.4 8.4 15.0 2.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit LXG PF04740.12 EMT54210.1 - 0.11 12.1 10.3 0.17 11.6 7.9 2.4 1 1 1 2 2 2 0 LXG domain of WXG superfamily HMMR_N PF15905.5 EMT54210.1 - 0.12 11.8 10.6 0.031 13.8 5.6 2.2 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal CCDC144C PF14915.6 EMT54210.1 - 0.15 11.2 8.3 0.039 13.1 4.4 1.9 1 1 0 2 2 2 0 CCDC144C protein coiled-coil region DUF1664 PF07889.12 EMT54210.1 - 0.18 11.8 10.6 0.45 10.6 2.4 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 EMT54210.1 - 0.19 11.7 12.1 1 9.4 1.0 3.8 2 1 2 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.17 EMT54210.1 - 0.22 11.4 5.1 24 4.8 1.8 3.9 1 1 0 3 3 3 0 Prefoldin subunit Spc7 PF08317.11 EMT54210.1 - 0.29 10.0 16.0 0.55 9.0 7.4 2.9 1 1 0 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 EMT54210.1 - 0.31 10.4 6.7 0.1 11.9 1.1 2.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 EMT54210.1 - 0.35 11.1 11.0 12 6.3 1.5 5.3 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.8 EMT54210.1 - 0.42 10.8 8.1 2.4 8.4 0.7 3.9 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding CREPT PF16566.5 EMT54210.1 - 0.59 10.3 10.2 0.63 10.2 3.0 3.3 2 1 2 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour DASH_Dad2 PF08654.10 EMT54210.1 - 0.8 10.2 14.5 5.7 7.4 0.1 4.6 2 1 1 4 4 4 0 DASH complex subunit Dad2 ZapB PF06005.12 EMT54210.1 - 1 9.9 8.1 15 6.1 1.9 3.7 3 1 0 3 3 2 0 Cell division protein ZapB RRF PF01765.19 EMT54210.1 - 1 9.3 5.4 0.92 9.4 0.9 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Jnk-SapK_ap_N PF09744.9 EMT54210.1 - 1.1 9.5 8.4 0.67 10.2 5.4 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ISG65-75 PF11727.8 EMT54210.1 - 1.2 8.4 8.3 0.2 10.9 2.5 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein Sec8_exocyst PF04048.14 EMT54210.1 - 1.3 8.9 9.9 2.4 8.0 1.3 3.9 2 2 2 4 4 4 0 Sec8 exocyst complex component specific domain DASH_Dam1 PF08653.10 EMT54210.1 - 1.3 8.9 3.9 8.1 6.3 0.0 4.3 4 1 0 4 4 4 0 DASH complex subunit Dam1 KASH_CCD PF14662.6 EMT54210.1 - 1.3 8.8 10.9 16 5.3 0.1 3.3 1 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH TMPIT PF07851.13 EMT54210.1 - 1.4 8.1 9.4 4.5 6.4 2.0 3.0 1 1 2 3 3 3 0 TMPIT-like protein COG5 PF10392.9 EMT54210.1 - 1.5 9.0 14.4 0.65 10.2 2.9 4.4 2 1 5 7 7 7 0 Golgi transport complex subunit 5 Tropomyosin_1 PF12718.7 EMT54210.1 - 1.6 8.8 8.4 3.7 7.7 3.0 3.2 2 1 0 3 3 3 0 Tropomyosin like Baculo_PEP_C PF04513.12 EMT54210.1 - 1.7 8.6 20.7 0.045 13.8 5.3 4.0 1 1 2 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BST2 PF16716.5 EMT54210.1 - 2.2 8.9 12.5 0.29 11.8 3.4 3.4 2 1 0 3 3 3 0 Bone marrow stromal antigen 2 SKA1 PF07160.12 EMT54210.1 - 2.7 7.8 7.4 2.5 7.9 2.4 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 YscO PF07321.12 EMT54210.1 - 3 7.8 12.7 3.9 7.4 2.6 3.3 3 0 0 3 3 3 0 Type III secretion protein YscO Fez1 PF06818.15 EMT54210.1 - 3.7 8.0 12.9 63 3.9 0.1 3.0 1 1 1 2 2 2 0 Fez1 Lebercilin PF15619.6 EMT54210.1 - 3.9 7.1 13.1 2.8 7.6 6.5 2.9 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Sec34 PF04136.15 EMT54210.1 - 4.3 7.2 7.2 11 5.9 3.5 3.1 2 1 1 3 3 3 0 Sec34-like family Fib_alpha PF08702.10 EMT54210.1 - 4.7 7.4 12.1 0.37 11.0 3.9 3.0 3 1 1 4 4 2 0 Fibrinogen alpha/beta chain family DUF4618 PF15397.6 EMT54210.1 - 5 6.5 9.6 5 6.5 6.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Cluap1 PF10234.9 EMT54210.1 - 7.6 5.8 9.2 15 4.9 8.2 2.0 1 1 0 1 1 1 0 Clusterin-associated protein-1 YabA PF06156.13 EMT54210.1 - 9.7 6.9 5.7 81 3.9 0.0 3.6 1 1 1 3 3 3 0 Initiation control protein YabA UPF0242 PF06785.11 EMT54210.1 - 9.7 6.2 14.9 7.3 6.6 0.0 3.3 2 1 0 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus TrkH PF02386.16 EMT54211.1 - 1.2e-58 198.8 31.8 1.8e-58 198.2 31.8 1.3 1 0 0 1 1 1 1 Cation transport protein Mg_chelatase_C PF13335.6 EMT54212.1 - 3.2e-35 120.6 1.7 3.7e-35 120.4 1.7 1.0 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal SRAP PF02586.14 EMT54213.1 - 1e-69 234.4 0.0 1.2e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) PLDc_2 PF13091.6 EMT54214.1 - 1.5e-30 105.8 0.1 2.2e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 EMT54214.1 - 8.8e-07 28.7 0.4 3.2e-05 23.6 0.4 2.1 1 1 0 1 1 1 1 FAM83 A-H Regulator_TrmB PF11495.8 EMT54214.1 - 8.2e-05 21.9 0.0 0.00011 21.5 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB Ada_Zn_binding PF02805.16 EMT54214.1 - 0.00017 21.6 0.2 0.00037 20.4 0.2 1.6 1 0 0 1 1 1 1 Metal binding domain of Ada PLDc PF00614.22 EMT54214.1 - 0.002 18.2 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif PP_kinase_C PF13090.6 EMT54214.1 - 0.15 11.5 0.3 0.48 9.9 0.1 1.8 2 0 0 2 2 2 0 Polyphosphate kinase C-terminal domain 2 E1_dh PF00676.20 EMT54215.1 - 0.049 12.6 0.1 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 Dehydrogenase E1 component DUF2072 PF09845.9 EMT54215.1 - 0.1 12.9 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF1906 PF08924.11 EMT54216.1 - 5.5e-30 105.0 2.6 7.9e-30 104.5 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1906) Alkyl_sulf_dimr PF14863.6 EMT54216.1 - 0.014 15.9 0.1 0.033 14.6 0.1 1.6 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Holin_SPP1 PF04688.13 EMT54217.1 - 0.00079 19.6 0.8 0.00095 19.3 0.8 1.1 1 0 0 1 1 1 1 SPP1 phage holin SLATT_1 PF18181.1 EMT54217.1 - 0.062 13.2 0.4 0.073 13.0 0.4 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Holin_BhlA PF10960.8 EMT54218.1 - 2e-16 59.7 0.1 2.8e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 BhlA holin family DUF2856 PF11043.8 EMT54218.1 - 0.017 15.2 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) ADH_N_assoc PF13823.6 EMT54219.1 - 3.2 7.8 5.3 1 9.4 0.6 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated PQQ_2 PF13360.6 EMT54220.1 - 1.6e-05 24.6 0.2 0.012 15.3 0.1 2.5 1 1 2 3 3 3 2 PQQ-like domain SBBP PF06739.11 EMT54220.1 - 0.025 14.6 0.1 0.23 11.5 0.1 2.8 1 0 0 1 1 1 0 Beta-propeller repeat Reg_prop PF07494.11 EMT54220.1 - 0.034 14.3 0.1 0.46 10.9 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller HZS_alpha PF18582.1 EMT54220.1 - 0.065 13.7 0.1 0.73 10.4 0.0 2.6 3 0 0 3 3 3 0 Hydrazine synthase alpha subunit middle domain DsbG_N PF18257.1 EMT54220.1 - 0.08 13.1 0.3 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Disulfide isomerase DsbG N-terminal PQQ PF01011.21 EMT54220.1 - 0.11 12.5 3.2 0.53 10.3 0.6 3.4 3 1 0 3 3 3 0 PQQ enzyme repeat DUF4376 PF14301.6 EMT54222.1 - 1.6e-13 50.9 0.7 3.2e-13 49.9 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4376) OSCP PF00213.18 EMT54223.1 - 0.043 13.9 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit IL31 PF15209.6 EMT54223.1 - 0.17 11.7 0.3 10 5.9 0.0 2.2 1 1 1 2 2 2 0 Interleukin 31 DUF3751 PF12571.8 EMT54225.1 - 8.2e-63 211.0 0.3 1.5e-62 210.1 0.3 1.5 1 0 0 1 1 1 1 Phage tail-collar fibre protein Queuosine_synth PF02547.15 EMT54225.1 - 0.094 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein DUF2313 PF10076.9 EMT54226.1 - 0.014 15.2 0.0 0.043 13.7 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) Baseplate_J PF04865.14 EMT54227.1 - 1.4e-23 83.3 1.5 6.6e-23 81.2 0.8 2.0 1 1 1 2 2 2 1 Baseplate J-like protein DUF3168 PF11367.8 EMT54227.1 - 0.017 15.3 0.1 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) DUF2634 PF10934.8 EMT54228.1 - 9.7e-18 64.2 0.7 1.1e-17 64.0 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2634) DUF2577 PF10844.8 EMT54229.1 - 0.0011 19.1 0.0 0.1 12.8 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2577) Com_YlbF PF06133.11 EMT54232.1 - 3.6e-05 24.3 4.6 0.0029 18.2 3.6 2.9 2 0 0 2 2 2 1 Control of competence regulator ComK, YlbF/YmcA Gly-zipper_Omp PF13488.6 EMT54232.1 - 0.0059 16.6 26.3 0.0059 16.6 26.3 3.3 4 0 0 4 4 4 1 Glycine zipper Iron_permease PF04120.12 EMT54232.1 - 0.086 12.6 0.8 0.79 9.5 0.4 2.6 2 1 1 3 3 3 0 Low affinity iron permease ABC_tran_CTD PF16326.5 EMT54232.1 - 0.14 12.4 1.1 16 5.8 0.3 3.8 2 1 2 4 4 4 0 ABC transporter C-terminal domain Tup_N PF08581.10 EMT54232.1 - 0.14 12.4 3.5 0.32 11.3 0.7 2.8 3 0 0 3 3 3 0 Tup N-terminal ZapD PF07072.11 EMT54232.1 - 0.41 10.4 2.0 24 4.6 0.0 3.0 3 1 0 3 3 3 0 Cell division protein DUF724 PF05266.14 EMT54232.1 - 0.45 10.3 9.8 0.35 10.7 4.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) HIP1_clath_bdg PF16515.5 EMT54232.1 - 0.51 11.0 5.5 0.64 10.7 2.4 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Syntaxin-6_N PF09177.11 EMT54232.1 - 0.58 10.7 2.7 0.62 10.6 0.6 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal PCRF PF03462.18 EMT54232.1 - 1.2 9.0 6.8 3.4 7.5 1.1 2.5 2 0 0 2 2 2 0 PCRF domain FAM184 PF15665.5 EMT54232.1 - 2.2 8.0 10.0 0.51 10.1 5.4 2.1 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B DUF3450 PF11932.8 EMT54232.1 - 5.3 6.3 9.1 0.12 11.6 1.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DHHC PF01529.20 EMT54233.1 - 5.1 7.2 6.6 5.9 7.0 6.6 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Phage_TAC_5 PF08890.11 EMT54234.1 - 5.4e-08 32.9 0.5 7.4e-08 32.5 0.5 1.3 1 1 0 1 1 1 1 Phage XkdN-like tail assembly chaperone protein, TAC Synaphin PF05835.12 EMT54234.1 - 0.016 15.5 0.2 0.027 14.7 0.2 1.3 1 0 0 1 1 1 0 Synaphin protein DUF4245 PF14030.6 EMT54234.1 - 0.042 13.9 0.5 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) NfeD PF01957.18 EMT54234.1 - 0.044 14.2 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF2001 PF09393.10 EMT54235.1 - 0.00024 21.1 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Phage tail tube protein Porin_4 PF13609.6 EMT54235.1 - 0.065 13.0 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Gram-negative porin Phage_sheath_1 PF04984.14 EMT54236.1 - 9.8e-12 45.1 1.6 1.7e-11 44.3 1.6 1.4 1 0 0 1 1 1 1 Phage tail sheath protein subtilisin-like domain Phage_sheath_1C PF17482.2 EMT54236.1 - 9.7e-10 38.4 0.3 5.9e-09 35.8 0.1 2.4 2 1 0 2 2 2 1 Phage tail sheath C-terminal domain Phage_sheath_1N PF17481.2 EMT54236.1 - 0.0021 18.5 0.7 0.0063 17.0 0.7 1.9 1 0 0 1 1 1 1 Phage tail sheath protein beta-sandwich domain RuBisCO_small PF00101.20 EMT54236.1 - 0.033 14.2 0.1 0.45 10.6 0.0 2.4 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain PND PF17949.1 EMT54237.1 - 0.03 14.6 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 FANCM pseudonuclease domain HK97-gp10_like PF04883.12 EMT54239.1 - 5e-05 24.2 0.1 0.00019 22.3 0.0 1.8 2 0 0 2 2 2 1 Bacteriophage HK97-gp10, putative tail-component DUF3199 PF11436.8 EMT54241.1 - 8.8e-09 35.5 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3199) Phage_cap_P2 PF05125.12 EMT54243.1 - 6.8e-06 25.3 1.7 0.0076 15.3 0.1 2.5 2 1 0 2 2 2 2 Phage major capsid protein, P2 family HTH_30 PF13556.6 EMT54243.1 - 0.078 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Peptidase_S78_2 PF14550.6 EMT54244.1 - 2.1e-42 144.0 5.1 2.1e-42 144.0 5.1 1.9 2 0 0 2 2 2 1 Putative phage serine protease XkdF FlxA PF14282.6 EMT54244.1 - 0.00036 20.5 10.2 0.00058 19.8 4.1 2.6 1 1 1 2 2 2 1 FlxA-like protein Syntaxin-6_N PF09177.11 EMT54244.1 - 0.001 19.6 6.0 0.39 11.3 2.2 2.9 1 1 1 2 2 2 2 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 EMT54244.1 - 0.0037 17.3 3.6 0.009 16.1 1.2 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 EMT54244.1 - 0.004 17.5 5.7 0.4 11.1 0.6 3.0 1 1 1 2 2 2 2 Lipoprotein leucine-zipper DUF948 PF06103.11 EMT54244.1 - 0.035 14.3 4.5 1.2 9.5 1.3 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Glycos_trans_3N PF02885.17 EMT54244.1 - 0.046 13.6 1.0 0.98 9.3 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Allexi_40kDa PF05549.11 EMT54244.1 - 0.059 12.9 3.5 0.1 12.1 2.5 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein ATP-cone PF03477.16 EMT54244.1 - 0.13 12.9 10.1 0.32 11.6 2.4 3.5 3 1 0 3 3 3 0 ATP cone domain GvpL_GvpF PF06386.11 EMT54244.1 - 0.17 11.8 5.5 0.33 10.8 5.5 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF YlqD PF11068.8 EMT54244.1 - 0.18 12.2 6.1 0.11 12.8 1.5 2.6 2 1 0 2 2 2 0 YlqD protein DUF1664 PF07889.12 EMT54244.1 - 0.19 11.8 3.8 0.25 11.4 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) P4Ha_N PF08336.11 EMT54244.1 - 0.36 10.8 4.5 7.4 6.6 0.0 3.4 2 1 3 5 5 5 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region SpecificRecomb PF10136.9 EMT54244.1 - 0.91 7.8 2.6 1.2 7.3 2.6 1.1 1 0 0 1 1 1 0 Site-specific recombinase NPV_P10 PF05531.12 EMT54244.1 - 1.3 9.5 7.3 19 5.8 4.2 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GIT_CC PF16559.5 EMT54244.1 - 1.4 8.9 5.2 5.5 6.9 0.7 3.0 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 EMT54244.1 - 1.6 8.0 9.0 3.3 7.0 9.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.8 EMT54244.1 - 1.7 7.1 6.4 2.5 6.6 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FAM76 PF16046.5 EMT54244.1 - 2 7.7 4.9 3.6 6.9 4.9 1.4 1 0 0 1 1 1 0 FAM76 protein DUF2894 PF11445.8 EMT54244.1 - 2 8.8 7.3 3.6 8.0 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Spc7 PF08317.11 EMT54244.1 - 2.7 6.8 9.8 1.2 8.0 6.4 1.8 1 1 0 2 2 2 0 Spc7 kinetochore protein Sas10_Utp3 PF04000.15 EMT54244.1 - 3.8 8.2 8.6 12 6.6 0.2 3.3 3 0 0 3 3 3 0 Sas10/Utp3/C1D family DUF5339 PF17274.2 EMT54244.1 - 9.1 7.2 7.4 1.5 9.8 0.4 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5339) Phage_Mu_F PF04233.14 EMT54245.1 - 5.1e-10 40.1 0.2 1.4e-09 38.7 0.1 1.9 2 1 0 2 2 2 1 Phage Mu protein F like protein Phage_portal PF04860.12 EMT54246.1 - 1.7e-10 40.6 0.1 2.8e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Phage portal protein tRNA_bind_3 PF17176.4 EMT54246.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 tRNA-binding domain AAA_30 PF13604.6 EMT54247.1 - 2.3e-06 27.5 0.0 3.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMT54247.1 - 9.6e-05 22.8 0.0 0.00022 21.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EMT54247.1 - 0.00058 19.8 0.0 0.00099 19.0 0.0 1.3 1 0 0 1 1 1 1 Helicase Terminase_3 PF04466.13 EMT54247.1 - 0.004 16.7 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 Phage terminase large subunit Terminase_6 PF03237.15 EMT54247.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Terminase-like family PhoH PF02562.16 EMT54247.1 - 0.072 12.5 0.0 0.74 9.2 0.0 2.4 1 1 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 EMT54247.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase Sigma70_r4 PF04545.16 EMT54248.1 - 0.024 14.1 1.6 7.8 6.1 0.1 3.0 3 0 0 3 3 3 0 Sigma-70, region 4 zf-primase PF09329.11 EMT54248.1 - 0.21 11.4 2.0 0.45 10.4 2.0 1.5 1 0 0 1 1 1 0 Primase zinc finger DNA_methylase PF00145.17 EMT54251.1 - 8.4e-40 137.1 0.0 9.4e-34 117.2 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase ParBc PF02195.18 EMT54252.1 - 2.2e-09 37.5 0.0 3.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 ParB-like nuclease domain Peptidase_C70 PF12385.8 EMT54254.1 - 2.5e-15 56.7 0.0 3.2e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 EMT54254.1 - 2e-11 44.6 2.1 5.4e-11 43.2 2.1 1.6 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C10 PF01640.17 EMT54254.1 - 0.016 15.5 0.3 0.025 14.9 0.3 1.4 1 0 0 1 1 1 0 Peptidase C10 family LemA PF04011.12 EMT54255.1 - 0.0051 16.7 2.8 0.007 16.2 2.8 1.1 1 0 0 1 1 1 1 LemA family Glu_cys_ligase PF04262.14 EMT54255.1 - 0.025 13.2 2.3 0.03 13.0 2.3 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase YbaJ PF10757.9 EMT54257.1 - 0.0025 18.4 0.7 0.0042 17.6 0.7 1.6 1 1 0 1 1 1 1 Biofilm formation regulator YbaJ TROVE PF05731.11 EMT54257.1 - 0.05 12.6 0.0 0.063 12.3 0.0 1.0 1 0 0 1 1 1 0 TROVE domain TRF PF08558.10 EMT54257.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Radical_SAM PF04055.21 EMT54260.1 - 0.0019 18.6 0.5 0.013 15.9 0.5 2.4 1 1 0 1 1 1 1 Radical SAM superfamily DNA_methylase PF00145.17 EMT54261.1 - 3.1e-26 92.5 0.0 9.9e-19 67.9 0.0 2.3 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase DUF3474 PF11960.8 EMT54261.1 - 0.1 12.8 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) FLgD_tudor PF13861.6 EMT54263.1 - 0.058 13.6 0.6 0.82 9.9 0.1 2.4 1 1 1 2 2 2 0 FlgD Tudor-like domain SDA1 PF05285.12 EMT54263.1 - 0.11 11.9 8.7 0.12 11.8 8.7 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EMT54263.1 - 0.25 9.6 4.1 0.24 9.7 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 EMT54263.1 - 0.32 10.1 6.6 0.42 9.7 6.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Nop14 PF04147.12 EMT54263.1 - 0.42 8.8 10.9 0.51 8.5 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 EMT54263.1 - 8.3 5.9 12.1 11 5.5 12.1 1.2 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 EMT54263.1 - 9.5 4.9 6.6 1.8 7.2 3.5 1.4 2 0 0 2 2 2 0 Presenilin RusA PF05866.11 EMT54264.1 - 3.7e-08 34.0 1.9 4.9e-08 33.6 1.2 1.6 1 1 0 1 1 1 1 Endodeoxyribonuclease RusA UPF0158 PF03682.13 EMT54264.1 - 0.0098 15.9 0.2 0.019 14.9 0.1 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0158) DnaB_C PF03796.15 EMT54265.1 - 2.3e-77 259.8 0.0 3.1e-77 259.4 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 EMT54265.1 - 8.3e-27 93.3 0.0 2.4e-26 91.8 0.0 1.8 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 EMT54265.1 - 6.9e-10 38.8 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EMT54265.1 - 0.0063 15.8 0.1 0.01 15.1 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Monellin PF09200.10 EMT54265.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Monellin RepL PF05732.11 EMT54266.1 - 0.055 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) GntR PF00392.21 EMT54266.1 - 0.058 13.1 0.0 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family FPP PF05911.11 EMT54267.1 - 0.00019 19.8 1.4 0.00023 19.5 1.4 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Prefoldin_2 PF01920.20 EMT54267.1 - 0.15 12.0 2.6 0.4 10.7 1.6 1.8 2 0 0 2 2 2 0 Prefoldin subunit SSB PF00436.25 EMT54268.1 - 3.1e-39 133.2 0.1 3.6e-39 133.0 0.1 1.0 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 EMT54268.1 - 0.00025 21.0 0.1 0.00036 20.5 0.1 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EMT54268.1 - 0.0055 16.9 0.0 0.007 16.5 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Dehalogenase PF13486.6 EMT54268.1 - 0.018 14.4 0.0 0.021 14.2 0.0 1.0 1 0 0 1 1 1 0 Reductive dehalogenase subunit ERF PF04404.12 EMT54269.1 - 2.7e-25 89.0 4.9 3.6e-25 88.6 4.9 1.2 1 0 0 1 1 1 1 ERF superfamily Phage_Mu_Gam PF07352.12 EMT54270.1 - 1.3e-34 119.4 3.5 1.5e-34 119.2 3.5 1.1 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Sipho_Gp157 PF05565.11 EMT54270.1 - 0.0074 16.3 3.9 0.016 15.2 3.9 1.7 1 1 0 1 1 1 1 Siphovirus Gp157 DUF3253 PF11625.8 EMT54270.1 - 0.15 12.3 1.1 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) HTH_19 PF12844.7 EMT54273.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EMT54273.1 - 0.0075 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix LpxD PF04613.14 EMT54273.1 - 0.097 12.5 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD HTH_3 PF01381.22 EMT54275.1 - 1.4e-13 50.6 0.0 1.8e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EMT54275.1 - 6.9e-13 48.4 0.0 8.6e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EMT54275.1 - 1.2e-08 35.2 0.0 1.5e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 EMT54275.1 - 0.086 12.7 0.1 0.21 11.4 0.1 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 EMT54276.1 - 2.2e-15 56.4 0.0 4.1e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EMT54276.1 - 6.5e-14 51.7 0.3 1.2e-13 50.8 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EMT54276.1 - 8.9e-11 42.0 0.0 1.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EMT54276.1 - 0.0044 17.4 0.0 0.0068 16.8 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HSCB_C PF07743.13 EMT54276.1 - 0.05 14.1 4.2 0.11 13.0 0.6 2.3 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain MTBP_N PF14918.6 EMT54277.1 - 0.08 12.4 0.1 0.13 11.7 0.1 1.4 1 1 0 1 1 1 0 MDM2-binding ACP_PD PF04336.12 EMT54278.1 - 0.055 13.9 1.2 0.66 10.4 0.2 2.7 2 1 1 3 3 3 0 Acyl carrier protein phosphodiesterase YtxH PF12732.7 EMT54278.1 - 0.056 14.0 0.1 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 YtxH-like protein TBPIP PF07106.13 EMT54279.1 - 0.06 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain CdiI_2 PF18593.1 EMT54279.1 - 0.068 13.8 0.3 0.31 11.7 0.1 2.0 2 0 0 2 2 2 0 CdiI immunity protein MarR_2 PF12802.7 EMT54279.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 MarR family Ribosomal_S16 PF00886.19 EMT54279.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S16 CN_hydrolase PF00795.22 EMT54280.1 - 0.0023 17.3 0.0 0.0047 16.3 0.0 1.5 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 EMT54281.1 - 0.14 11.0 16.1 0.11 11.4 13.8 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily COX15-CtaA PF02628.15 EMT54281.1 - 0.18 10.8 4.1 0.22 10.6 1.1 2.0 1 1 1 2 2 2 0 Cytochrome oxidase assembly protein Ost5 PF05251.12 EMT54281.1 - 0.47 10.8 12.4 1.1 9.6 0.9 3.7 3 2 0 3 3 3 0 Oligosaccharyltransferase subunit 5 DUF2157 PF09925.9 EMT54281.1 - 4.1 7.2 10.4 0.22 11.3 2.7 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF2207 PF09972.9 EMT54281.1 - 7.8 5.1 16.4 5.2e+02 -0.9 16.5 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) HNH PF01844.23 EMT54282.1 - 5.5e-09 36.1 0.2 1.1e-08 35.0 0.2 1.6 1 0 0 1 1 1 1 HNH endonuclease DZR PF12773.7 EMT54282.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon EPV_E5 PF08135.11 EMT54283.1 - 0.41 11.1 4.8 0.98 9.8 4.8 1.6 1 0 0 1 1 1 0 Major transforming protein E5 family Peptidase_M78 PF06114.13 EMT54284.1 - 1e-08 35.2 0.2 1.1e-08 35.0 0.2 1.1 1 0 0 1 1 1 1 IrrE N-terminal-like domain DUF493 PF04359.14 EMT54284.1 - 0.034 14.7 0.0 0.29 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF493) Mrr_cat PF04471.12 EMT54285.1 - 6.4e-32 110.0 0.0 1.5e-31 108.8 0.0 1.7 1 0 0 1 1 1 1 Restriction endonuclease DUF3450 PF11932.8 EMT54285.1 - 0.42 9.9 20.6 0.048 13.0 10.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2797 PF10977.8 EMT54285.1 - 2.6 7.9 8.6 0.27 11.1 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) L27_1 PF09058.10 EMT54285.1 - 5.4 7.1 13.2 22 5.1 4.2 3.4 2 1 0 2 2 2 0 L27_1 Pinin_SDK_memA PF04696.13 EMT54285.1 - 7.6 6.6 28.3 0.27 11.3 16.0 2.4 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Resolvase PF00239.21 EMT54286.1 - 2.4e-36 125.1 0.2 6.5e-36 123.6 0.0 1.9 2 0 0 2 2 2 1 Resolvase, N terminal domain Recombinase PF07508.13 EMT54286.1 - 6.8e-21 74.6 0.1 2.6e-20 72.8 0.1 2.0 1 0 0 1 1 1 1 Recombinase Zn_ribbon_recom PF13408.6 EMT54286.1 - 1.4e-10 41.5 4.3 3e-10 40.4 4.3 1.5 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Prefoldin_2 PF01920.20 EMT54286.1 - 0.0049 16.8 8.4 0.007 16.3 2.8 2.6 2 0 0 2 2 2 1 Prefoldin subunit Salt_tol_Pase PF09506.10 EMT54286.1 - 0.01 14.6 2.6 0.017 13.9 2.6 1.2 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) FlaC_arch PF05377.11 EMT54286.1 - 0.096 13.1 6.2 1.2 9.6 1.8 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4349 PF14257.6 EMT54286.1 - 0.22 11.0 4.5 0.4 10.1 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Occludin_ELL PF07303.13 EMT54286.1 - 0.61 10.9 4.5 1.6 9.5 3.5 2.2 1 1 1 2 2 2 0 Occludin homology domain Fungal_TACC PF12709.7 EMT54286.1 - 3.7 8.1 7.9 23 5.5 1.3 2.7 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spc24 PF08286.11 EMT54286.1 - 5 7.4 13.3 0.66 10.2 5.7 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 zf-C4H2 PF10146.9 EMT54286.1 - 10 6.4 8.9 18 5.6 8.9 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Mg_chelatase PF01078.21 EMT54287.1 - 7.5e-70 234.5 0.0 9.8e-70 234.1 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 EMT54287.1 - 5.2e-49 165.1 0.0 7.6e-49 164.6 0.0 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EMT54287.1 - 1.2e-08 35.1 0.0 2.7e-08 33.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) Lon_C PF05362.13 EMT54287.1 - 4.6e-08 32.8 0.0 9.5e-08 31.8 0.0 1.4 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain Sigma54_activat PF00158.26 EMT54287.1 - 6.5e-07 29.2 0.0 0.0019 18.0 0.0 2.1 2 0 0 2 2 2 2 Sigma-54 interaction domain MCM PF00493.23 EMT54287.1 - 2.3e-05 23.6 0.0 0.0024 17.0 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 EMT54287.1 - 0.00052 20.4 0.0 0.002 18.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EMT54287.1 - 0.00052 19.8 0.0 0.075 12.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 EMT54287.1 - 0.0018 18.4 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 EMT54287.1 - 0.003 18.0 0.2 0.014 15.9 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EMT54287.1 - 0.0079 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EMT54287.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EMT54287.1 - 0.048 13.8 0.0 0.73 9.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EMT54287.1 - 0.06 13.6 0.0 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMT54287.1 - 0.062 13.5 0.1 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMT54287.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMT54287.1 - 0.12 12.0 0.1 0.7 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EMT54287.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EMT54287.1 - 0.18 12.3 0.0 0.31 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EMT54287.1 - 0.23 11.0 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Polysacc_deac_1 PF01522.21 EMT54289.1 - 1.3e-37 128.4 0.0 2.2e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EMT54289.1 - 0.00013 21.3 0.4 0.00039 19.7 0.2 1.5 1 1 0 2 2 2 1 Glycosyl hydrolase family 57 RNase_T PF00929.24 EMT54290.1 - 2.5e-09 37.9 0.0 9.4e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 Exonuclease Zn_Tnp_IS91 PF14319.6 EMT54290.1 - 0.013 15.5 3.0 0.024 14.6 3.0 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain RlaP PF10127.9 EMT54291.1 - 2.9e-93 312.0 1.2 3.2e-93 311.8 1.2 1.0 1 0 0 1 1 1 1 RNA repair pathway DNA polymerase beta family TAP_C PF03943.13 EMT54291.1 - 0.043 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 TAP C-terminal domain Polbeta PF18765.1 EMT54291.1 - 0.1 12.7 0.7 0.19 11.8 0.1 1.9 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase IF4E PF01652.18 EMT54292.1 - 0.1 12.4 0.0 9.9 5.9 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic initiation factor 4E UPF0102 PF02021.17 EMT54293.1 - 7.3e-29 99.8 0.3 9.4e-29 99.5 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 NERD PF08378.11 EMT54293.1 - 2.5e-07 31.1 0.0 2.7e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Nuclease-related domain NucS PF01939.16 EMT54293.1 - 0.0024 17.3 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease NucS MliC PF09864.9 EMT54293.1 - 0.02 14.8 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Mrr_cat PF04471.12 EMT54293.1 - 0.03 14.4 0.1 0.046 13.7 0.1 1.5 1 1 0 1 1 1 0 Restriction endonuclease HP_OMP PF01856.17 EMT54293.1 - 0.079 13.0 0.0 0.089 12.9 0.0 1.1 1 0 0 1 1 1 0 Helicobacter outer membrane protein Bac_export_2 PF01312.19 EMT54294.1 - 1.4e-20 73.8 0.8 1.6e-20 73.6 0.8 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family Flg_hook PF02120.16 EMT54295.1 - 0.0012 18.6 0.0 0.0012 18.6 0.0 2.6 3 0 0 3 3 3 1 Flagellar hook-length control protein FliK RNase_HII PF01351.18 EMT54296.1 - 1.4e-35 123.0 0.1 2.5e-35 122.1 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease HII TDRP PF15683.5 EMT54296.1 - 0.13 12.3 1.1 0.21 11.6 1.1 1.3 1 0 0 1 1 1 0 Testis development-related protein MMR_HSR1 PF01926.23 EMT54297.1 - 9.7e-17 61.1 0.0 2.7e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMT54297.1 - 1.3e-07 31.7 0.0 3.6e-05 23.7 0.0 2.4 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EMT54297.1 - 3.7e-07 29.8 0.0 7.7e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 EMT54297.1 - 0.00039 19.9 0.1 0.02 14.4 0.0 2.3 1 1 1 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.23 EMT54297.1 - 0.00096 19.2 0.0 0.083 12.9 0.0 2.4 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.10 EMT54297.1 - 0.0024 17.3 0.0 0.0089 15.5 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 EMT54297.1 - 0.0035 16.4 0.2 0.014 14.4 0.1 1.9 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EMT54297.1 - 0.0048 17.5 0.0 0.017 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMT54297.1 - 0.005 17.2 0.3 0.032 14.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 EMT54297.1 - 0.0067 15.8 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 EMT54297.1 - 0.0086 16.3 0.0 0.024 14.8 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EMT54297.1 - 0.016 14.8 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Ras family TniB PF05621.11 EMT54297.1 - 0.084 12.3 0.4 0.23 10.8 0.0 1.9 3 0 0 3 3 3 0 Bacterial TniB protein AAA_28 PF13521.6 EMT54297.1 - 0.09 13.0 0.0 0.76 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EMT54297.1 - 0.1 12.1 0.0 16 5.0 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Baculo_FP PF03258.14 EMT54297.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Baculovirus FP protein G-alpha PF00503.20 EMT54297.1 - 0.17 11.0 0.0 4.3 6.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 EMT54297.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_S24 PF00717.23 EMT54298.1 - 4.8e-17 61.7 0.2 7.2e-17 61.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EMT54298.1 - 1.5e-13 50.7 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 DUF2798 PF11391.8 EMT54298.1 - 0.047 13.7 0.3 0.073 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) Ribosomal_L19 PF01245.20 EMT54299.1 - 7.2e-54 180.5 6.2 8.1e-54 180.3 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 tRNA_m1G_MT PF01746.21 EMT54300.1 - 2.5e-72 242.7 0.0 2.9e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase SPOUT_MTase PF02590.17 EMT54300.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase RimM PF01782.18 EMT54301.1 - 6.5e-21 74.4 0.0 1.1e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 EMT54301.1 - 4e-12 46.0 0.3 7e-12 45.3 0.3 1.4 1 0 0 1 1 1 1 PRC-barrel domain YlqD PF11068.8 EMT54302.1 - 6.6e-35 120.4 14.1 7.3e-35 120.2 14.1 1.0 1 0 0 1 1 1 1 YlqD protein DUF812 PF05667.11 EMT54302.1 - 0.019 13.8 8.4 0.022 13.7 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ATP-synt_B PF00430.18 EMT54302.1 - 0.065 13.3 8.7 0.087 12.9 8.7 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) HET-s_218-289 PF11558.8 EMT54302.1 - 0.11 12.5 0.1 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 Het-s 218-289 DUF1682 PF07946.14 EMT54302.1 - 5.9 6.0 10.6 7.1 5.7 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) KH_4 PF13083.6 EMT54303.1 - 2.3e-24 85.0 0.8 2.5e-24 84.9 0.8 1.0 1 0 0 1 1 1 1 KH domain KH_1 PF00013.29 EMT54303.1 - 0.00064 19.5 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 KH domain T7SS_ESX_EspC PF10824.8 EMT54303.1 - 0.036 14.5 0.2 0.071 13.6 0.1 1.5 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm KH_2 PF07650.17 EMT54303.1 - 0.073 12.9 0.7 0.11 12.4 0.7 1.4 1 1 0 1 1 1 0 KH domain Ribosomal_S16 PF00886.19 EMT54304.1 - 6.8e-24 83.7 0.1 8.3e-24 83.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 SRP54 PF00448.22 EMT54305.1 - 1.3e-80 269.6 0.7 2.8e-80 268.6 0.7 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EMT54305.1 - 1.5e-32 112.2 6.0 1.5e-32 112.2 6.0 2.6 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 EMT54305.1 - 1.8e-24 85.7 1.5 1.8e-24 85.7 1.5 3.6 4 0 0 4 4 4 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 EMT54305.1 - 3.2e-07 30.4 2.2 2.1e-06 27.8 0.2 2.7 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 EMT54305.1 - 2e-06 27.2 0.1 5.2e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_31 PF13614.6 EMT54305.1 - 3.1e-05 24.0 0.7 0.01 15.8 0.1 3.2 2 1 1 3 3 3 1 AAA domain cobW PF02492.19 EMT54305.1 - 0.00024 20.7 1.6 0.00024 20.7 1.6 2.1 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EMT54305.1 - 0.00039 20.2 1.7 0.00056 19.7 0.3 2.1 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.20 EMT54305.1 - 0.00044 20.2 0.1 0.012 15.6 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase ParA PF10609.9 EMT54305.1 - 0.0013 18.2 0.2 0.0067 15.9 0.0 2.1 1 1 1 2 2 2 1 NUBPL iron-transfer P-loop NTPase AAA_33 PF13671.6 EMT54305.1 - 0.0019 18.3 0.1 0.0064 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EMT54305.1 - 0.0023 17.5 0.6 1.8 8.1 0.0 2.4 1 1 1 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EMT54305.1 - 0.0026 17.8 1.4 0.015 15.4 0.7 2.6 2 1 0 2 2 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EMT54305.1 - 0.0031 17.3 0.9 0.08 12.7 0.0 2.8 3 1 0 3 3 3 1 Conserved hypothetical ATP binding protein Helicase_RecD PF05127.14 EMT54305.1 - 0.0043 16.9 0.7 0.022 14.6 0.1 2.3 2 0 0 2 2 2 1 Helicase CLP1_P PF16575.5 EMT54305.1 - 0.0045 16.8 0.5 4.1 7.2 0.1 2.7 3 0 0 3 3 3 2 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 EMT54305.1 - 0.0046 17.4 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain 6PF2K PF01591.18 EMT54305.1 - 0.008 15.5 0.1 0.027 13.8 0.0 1.9 1 1 1 2 2 2 1 6-phosphofructo-2-kinase AAA_22 PF13401.6 EMT54305.1 - 0.0086 16.3 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 EMT54305.1 - 0.0091 15.7 0.2 0.036 13.7 0.2 1.9 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 EMT54305.1 - 0.011 16.1 0.1 0.011 16.1 0.1 3.5 4 0 0 4 4 4 0 AAA domain KTI12 PF08433.10 EMT54305.1 - 0.017 14.6 1.0 0.46 9.9 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 EMT54305.1 - 0.067 13.1 2.7 1.8 8.5 0.2 2.6 2 0 0 2 2 2 0 NTPase Thymidylate_kin PF02223.17 EMT54305.1 - 0.071 12.8 2.1 0.075 12.7 0.1 2.1 2 0 0 2 2 1 0 Thymidylate kinase Tex_YqgF PF16921.5 EMT54305.1 - 0.11 12.9 0.2 1.7 9.1 0.1 2.3 2 0 0 2 2 2 0 Tex protein YqgF-like domain AAA_28 PF13521.6 EMT54305.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EMT54305.1 - 0.13 12.3 0.3 0.33 11.0 0.3 1.8 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ArsA_ATPase PF02374.15 EMT54305.1 - 0.16 11.1 0.1 0.16 11.1 0.1 3.7 2 2 1 4 4 4 0 Anion-transporting ATPase MeaB PF03308.16 EMT54305.1 - 0.21 10.5 5.8 0.48 9.4 0.4 3.0 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EMT54305.1 - 0.24 10.9 3.7 0.52 9.8 0.6 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_19 PF13245.6 EMT54305.1 - 0.59 10.5 3.3 0.96 9.8 2.5 2.0 1 1 0 1 1 1 0 AAA domain DUF3618 PF12277.8 EMT54305.1 - 1 9.7 3.9 3.1 8.1 0.0 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF3618) ResIII PF04851.15 EMT54305.1 - 1.2 9.2 5.0 0.85 9.6 1.3 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit LTXXQ PF07813.12 EMT54305.1 - 3.6 8.4 11.1 0.81 10.4 4.2 3.0 3 0 0 3 3 2 0 LTXXQ motif family protein UPF0122 PF04297.14 EMT54306.1 - 6e-33 113.1 1.6 6.9e-33 112.9 1.6 1.1 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4_2 PF08281.12 EMT54306.1 - 1.9e-09 37.1 0.2 1.9e-09 37.1 0.2 2.0 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT54306.1 - 8.5e-08 31.6 0.2 1.7e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.12 EMT54306.1 - 5.5e-05 23.0 0.0 9.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_28 PF13518.6 EMT54306.1 - 0.00011 22.2 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 EMT54306.1 - 0.0002 21.1 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 HTH DNA binding domain HTH_40 PF14493.6 EMT54306.1 - 0.00046 20.6 0.2 0.00051 20.5 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0175 PF03683.13 EMT54306.1 - 0.0012 18.5 0.2 0.0021 17.7 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) HTH_29 PF13551.6 EMT54306.1 - 0.0014 18.6 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 EMT54306.1 - 0.008 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Phage_antitermQ PF06530.12 EMT54306.1 - 0.0099 15.8 0.3 0.019 14.9 0.1 1.6 1 1 0 1 1 1 1 Phage antitermination protein Q MarR_2 PF12802.7 EMT54306.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_30 PF13556.6 EMT54306.1 - 0.016 15.0 0.2 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DUF4175 PF13779.6 EMT54306.1 - 0.079 10.9 3.9 0.09 10.7 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) HTH_24 PF13412.6 EMT54306.1 - 0.087 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SRP54 PF00448.22 EMT54307.1 - 2.6e-83 278.5 0.8 4.6e-83 277.7 0.8 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EMT54307.1 - 4.4e-14 52.5 4.4 4.4e-14 52.5 4.4 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 EMT54307.1 - 5.3e-05 23.0 0.9 0.00011 22.0 0.9 1.5 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 EMT54307.1 - 6.8e-05 22.0 0.4 0.00023 20.2 0.4 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EMT54307.1 - 8.2e-05 22.7 0.1 0.00041 20.4 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EMT54307.1 - 0.00013 21.9 0.1 0.00026 20.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMT54307.1 - 0.00032 21.1 1.4 0.0028 18.1 0.3 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EMT54307.1 - 0.0019 18.5 1.5 0.016 15.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EMT54307.1 - 0.0048 17.4 0.0 0.0092 16.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Fer4_NifH PF00142.18 EMT54307.1 - 0.0087 15.5 0.1 0.019 14.4 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.20 EMT54307.1 - 0.011 15.7 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 EMT54307.1 - 0.011 16.2 2.0 0.029 14.8 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EMT54307.1 - 0.013 15.9 0.5 0.059 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EMT54307.1 - 0.014 15.1 1.6 0.2 11.3 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain ArsA_ATPase PF02374.15 EMT54307.1 - 0.022 14.0 0.5 0.022 14.0 0.5 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_5 PF07728.14 EMT54307.1 - 0.025 14.6 0.2 0.09 12.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EMT54307.1 - 0.046 13.8 2.5 0.11 12.6 0.2 2.6 2 2 0 2 2 2 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 EMT54307.1 - 0.046 13.4 0.8 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 Thymidylate kinase AAA_33 PF13671.6 EMT54307.1 - 0.047 13.9 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMT54307.1 - 0.053 12.8 0.1 0.098 11.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.14 EMT54307.1 - 0.055 13.4 0.8 0.22 11.4 0.7 2.0 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PLU-1 PF08429.11 EMT54307.1 - 0.07 12.3 0.4 0.13 11.5 0.4 1.3 1 0 0 1 1 1 0 PLU-1-like protein KdpD PF02702.17 EMT54307.1 - 0.14 11.7 2.9 0.11 12.0 0.5 2.1 2 1 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain ATP_bind_1 PF03029.17 EMT54307.1 - 0.15 11.8 2.4 0.19 11.5 0.4 2.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EMT54307.1 - 0.17 12.4 0.6 6.1 7.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EMT54307.1 - 0.42 10.5 4.5 0.33 10.8 0.8 2.5 2 1 1 3 3 3 0 NTPase KIP1 PF07765.12 EMT54307.1 - 1.7 8.8 4.2 7.1 6.8 0.1 3.1 2 1 1 3 3 3 0 KIP1-like protein SMC_N PF02463.19 EMT54308.1 - 1.9e-78 262.9 0.0 3.5e-78 262.0 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EMT54308.1 - 1e-33 116.1 0.3 3.2e-33 114.5 0.3 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EMT54308.1 - 2.8e-15 57.4 13.4 2.8e-15 57.4 13.4 7.5 2 2 2 5 5 5 1 AAA domain AAA_15 PF13175.6 EMT54308.1 - 7.5e-15 55.5 25.8 4.6e-13 49.6 0.0 4.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EMT54308.1 - 4.9e-13 49.5 1.8 1.4e-05 25.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMT54308.1 - 0.00014 21.5 0.0 0.0003 20.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FhuF PF06276.12 EMT54308.1 - 0.053 13.9 1.2 23 5.4 0.0 3.4 2 1 0 2 2 2 0 Ferric iron reductase FhuF-like transporter Ribonucleas_3_3 PF14622.6 EMT54309.1 - 1.1e-36 125.8 0.0 2.1e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EMT54309.1 - 2.4e-20 73.1 0.0 5.3e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EMT54309.1 - 5.2e-18 65.5 0.0 9.2e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EMT54309.1 - 0.0038 17.5 0.1 0.01 16.1 0.1 1.7 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Phage_P2_GpU PF06995.11 EMT54309.1 - 0.044 13.4 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 Phage P2 GpU ketoacyl-synt PF00109.26 EMT54310.1 - 2.7e-66 223.7 3.5 5.4e-65 219.5 0.2 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMT54310.1 - 1.9e-39 134.3 1.0 1.9e-39 134.3 1.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EMT54310.1 - 0.00047 19.6 1.6 0.02 14.3 0.7 2.4 2 0 0 2 2 2 2 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EMT54310.1 - 0.019 15.4 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EMT54311.1 - 1.3e-16 60.7 1.4 1.5e-16 60.5 1.4 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EMT54311.1 - 2.3e-05 24.6 2.1 2.4e-05 24.5 2.1 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.12 EMT54311.1 - 0.11 12.9 0.3 0.13 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) adh_short_C2 PF13561.6 EMT54312.1 - 3.4e-76 255.9 6.7 3.8e-76 255.7 6.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT54312.1 - 3.9e-66 222.2 5.8 4.6e-66 222.0 5.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT54312.1 - 1.1e-23 84.1 1.5 1.6e-23 83.5 1.4 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMT54312.1 - 5.5e-05 22.7 0.5 0.00015 21.3 0.3 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EMT54312.1 - 0.013 14.8 0.2 0.033 13.5 0.2 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 EMT54312.1 - 0.013 14.8 0.4 0.028 13.8 0.4 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EMT54312.1 - 0.015 14.4 0.6 0.021 14.0 0.6 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SAM_LFY PF01698.16 EMT54312.1 - 0.071 13.1 1.1 10 6.2 0.1 2.6 1 1 1 2 2 2 0 Floricaula / Leafy protein SAM domain Acyl_transf_1 PF00698.21 EMT54313.1 - 2e-40 139.2 5.9 2.4e-40 139.0 5.9 1.0 1 0 0 1 1 1 1 Acyl transferase domain ACP_syn_III_C PF08541.10 EMT54314.1 - 1.6e-39 133.9 0.2 1.5e-38 130.8 0.0 2.5 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EMT54314.1 - 1.8e-27 95.0 0.3 4.4e-27 93.7 0.3 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EMT54314.1 - 2.4e-12 46.8 0.3 1.7e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Chal_sti_synt_C PF02797.15 EMT54314.1 - 0.00025 21.0 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain SpoVAD PF07451.11 EMT54314.1 - 0.00033 19.4 2.6 0.067 11.9 1.0 3.0 1 1 1 2 2 2 2 Stage V sporulation protein AD (SpoVAD) FAE1_CUT1_RppA PF08392.12 EMT54314.1 - 0.0031 16.9 0.1 0.68 9.2 0.0 2.1 2 0 0 2 2 2 2 FAE1/Type III polyketide synthase-like protein ketoacyl-synt PF00109.26 EMT54314.1 - 0.0037 16.9 2.7 0.86 9.1 0.1 2.9 1 1 2 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Peptidase_M22 PF00814.25 EMT54314.1 - 0.06 13.0 0.2 0.46 10.1 0.1 2.1 2 0 0 2 2 2 0 Glycoprotease family Thiolase_C PF02803.18 EMT54314.1 - 0.18 11.5 2.2 0.83 9.3 0.0 2.5 3 0 0 3 3 3 0 Thiolase, C-terminal domain FA_synthesis PF02504.15 EMT54315.1 - 1.4e-115 385.8 0.6 1.8e-115 385.5 0.6 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein HTH_DeoR PF08220.12 EMT54316.1 - 8.8e-05 22.2 0.1 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain 4HBT PF03061.22 EMT54316.1 - 0.00011 22.5 0.5 0.00018 21.8 0.5 1.4 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 EMT54316.1 - 0.0002 20.9 0.2 0.00036 20.1 0.2 1.4 1 0 0 1 1 1 1 MaoC like domain HTH_11 PF08279.12 EMT54316.1 - 0.0024 17.8 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 HTH domain Sigma54_AID PF00309.20 EMT54316.1 - 0.58 10.1 3.1 12 5.8 0.1 2.6 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) DeoRC PF00455.22 EMT54317.1 - 1.4e-42 145.4 0.0 1.8e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EMT54317.1 - 3.7e-17 61.8 0.1 1.4e-16 60.0 0.1 1.9 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EMT54317.1 - 7.9e-08 32.1 0.1 7.8e-07 28.9 0.2 2.2 2 0 0 2 2 2 1 HTH domain GntR PF00392.21 EMT54317.1 - 0.00011 21.8 0.3 0.00032 20.3 0.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family MarR PF01047.22 EMT54317.1 - 0.00013 21.8 0.1 0.00045 20.1 0.1 1.9 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EMT54317.1 - 0.0089 15.9 0.1 0.025 14.5 0.1 1.8 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EMT54317.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 EMT54317.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_36 PF13730.6 EMT54317.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 EMT54317.1 - 0.052 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator HTH_AsnC-type PF13404.6 EMT54317.1 - 0.052 13.4 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_28 PF13518.6 EMT54317.1 - 0.066 13.4 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain FeoC PF09012.10 EMT54317.1 - 0.11 12.5 0.0 0.6 10.2 0.0 2.0 2 0 0 2 2 2 0 FeoC like transcriptional regulator FaeA PF04703.12 EMT54317.1 - 0.24 11.8 1.0 2.9 8.3 0.0 2.3 1 1 1 2 2 2 0 FaeA-like protein Ribosomal_L32p PF01783.23 EMT54318.1 - 3.1e-27 94.6 5.3 3.4e-27 94.5 5.3 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 EMT54318.1 - 0.00047 19.5 6.0 0.014 14.8 5.9 2.1 1 1 1 2 2 2 2 zinc-ribbon domain HypA PF01155.19 EMT54318.1 - 0.001 19.1 0.4 0.001 19.1 0.4 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EMT54318.1 - 0.0019 18.2 0.4 0.0024 17.9 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-tcix PF14952.6 EMT54318.1 - 0.016 14.8 1.7 0.47 10.1 0.1 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Nop10p PF04135.12 EMT54318.1 - 0.019 15.0 0.6 0.019 15.0 0.6 1.8 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family zf-NADH-PPase PF09297.11 EMT54318.1 - 0.02 14.6 3.7 0.11 12.2 0.7 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ACC PF17848.1 EMT54318.1 - 0.11 12.6 4.5 3.4 7.8 0.3 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_4 PF13717.6 EMT54318.1 - 0.13 12.2 2.7 3.3 7.7 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-FPG_IleRS PF06827.14 EMT54318.1 - 0.14 12.0 3.5 4.2 7.3 0.1 2.4 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 EMT54318.1 - 0.14 12.3 4.1 0.71 10.0 4.0 2.0 1 1 1 2 2 2 0 Zinc ribbon domain TFIIS_C PF01096.18 EMT54318.1 - 0.17 11.8 2.2 6.9 6.6 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_2 PF13240.6 EMT54318.1 - 0.17 11.6 4.3 3.1 7.6 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 EMT54318.1 - 0.18 11.8 4.2 1.2 9.2 1.2 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain UPF0547 PF10571.9 EMT54318.1 - 0.44 10.7 4.1 0.54 10.4 0.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_7 PF02591.15 EMT54318.1 - 0.63 10.3 4.6 1.8 8.8 0.2 2.3 2 1 0 2 2 2 0 C4-type zinc ribbon domain Rubredoxin_2 PF18073.1 EMT54318.1 - 1.2 8.9 6.3 13 5.6 6.3 2.0 1 1 0 1 1 1 0 Rubredoxin metal binding domain ADK_lid PF05191.14 EMT54318.1 - 2.8 8.0 9.9 1.9 8.6 0.5 2.5 2 1 1 3 3 3 0 Adenylate kinase, active site lid YceD PF02620.17 EMT54319.1 - 2.1e-31 108.6 2.1 2.9e-31 108.1 2.1 1.2 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD PDZ_2 PF13180.6 EMT54320.1 - 2.1e-14 53.6 0.9 4.8e-14 52.4 0.3 1.9 2 0 0 2 2 2 1 PDZ domain Lon_C PF05362.13 EMT54320.1 - 1.5e-09 37.8 0.1 3e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain PDZ PF00595.24 EMT54320.1 - 7.3e-05 23.0 0.2 0.0002 21.7 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EMT54320.1 - 0.00034 20.4 0.0 0.00083 19.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EMT54320.1 - 0.00042 20.2 0.1 0.00096 19.1 0.1 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain Peptidase_M17 PF00883.21 EMT54320.1 - 0.024 13.9 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 Cytosol aminopeptidase family, catalytic domain DUF4251 PF14059.6 EMT54320.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4251) Patatin PF01734.22 EMT54321.1 - 9.1e-23 81.5 1.9 4e-20 72.9 1.9 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Gate PF07670.14 EMT54322.1 - 3.9e-09 36.8 17.1 7.9e-05 22.9 1.8 3.0 2 1 0 2 2 2 2 Nucleoside recognition CTP_transf_like PF01467.26 EMT54323.1 - 1.4e-19 70.7 0.0 1.6e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 EMT54323.1 - 2.4e-05 24.1 0.0 5.2e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Citrate lyase ligase C-terminal domain Cons_hypoth95 PF03602.15 EMT54324.1 - 2e-58 197.0 0.0 2.4e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 EMT54324.1 - 7.1e-06 25.7 0.0 9.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EMT54324.1 - 4.7e-05 23.0 0.0 6.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.6 EMT54324.1 - 0.0006 20.8 0.0 0.00091 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RsmJ PF04378.13 EMT54324.1 - 0.00071 18.9 0.0 0.00094 18.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ Methyltransf_31 PF13847.6 EMT54324.1 - 0.001 18.9 0.0 0.0014 18.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EMT54324.1 - 0.0012 18.6 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 EMT54324.1 - 0.006 16.3 0.0 0.067 12.9 0.0 2.0 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.13 EMT54324.1 - 0.0079 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 EMT54324.1 - 0.014 14.5 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase TRM PF02005.16 EMT54324.1 - 0.018 14.2 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase SAM_MT PF04445.13 EMT54324.1 - 0.056 12.9 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase N6-adenineMlase PF10237.9 EMT54324.1 - 0.16 11.8 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Ku PF02735.16 EMT54325.1 - 7.8e-43 146.6 0.3 3.3e-42 144.5 0.1 1.8 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Cation_efflux PF01545.21 EMT54326.1 - 1e-50 172.2 6.2 1.3e-50 171.9 6.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EMT54326.1 - 6.6e-18 64.6 4.8 1.2e-17 63.8 4.8 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter AzlD PF05437.12 EMT54326.1 - 8.2 6.7 9.1 6.3 7.0 5.0 2.7 2 1 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DNA_ligase_A_M PF01068.21 EMT54327.1 - 1.1e-30 106.8 0.0 1.6e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 EMT54327.1 - 4.4e-18 65.7 0.0 7.8e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 EMT54327.1 - 2.2e-07 30.9 0.1 0.011 15.6 0.0 2.9 2 1 0 3 3 3 2 mRNA capping enzyme, catalytic domain RNA_ligase PF09414.10 EMT54327.1 - 2.8e-06 27.7 0.0 5.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 RNA ligase MFS_1 PF07690.16 EMT54328.1 - 6.1e-33 114.2 73.4 3.1e-23 82.3 43.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMT54328.1 - 1.6e-08 33.6 25.6 3.1e-06 26.0 5.9 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 EMT54328.1 - 1.4e-06 27.5 30.4 4.8e-06 25.7 9.2 2.7 1 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EMT54328.1 - 4.9e-05 22.0 2.7 4.9e-05 22.0 2.7 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.18 EMT54328.1 - 0.00034 19.5 0.1 0.00034 19.5 0.1 2.2 3 0 0 3 3 3 1 Reduced folate carrier MASE5 PF17178.4 EMT54328.1 - 2.7 7.8 6.2 0.77 9.6 0.4 2.7 1 1 2 3 3 3 0 Membrane-associated sensor Spore_permease PF03845.13 EMT54329.1 - 9.7e-37 126.5 25.7 9.7e-37 126.5 25.7 1.8 2 0 0 2 2 2 1 Spore germination protein Hfq PF17209.3 EMT54330.1 - 0.084 12.5 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Hfq protein Spore_GerAC PF05504.11 EMT54331.1 - 5.5e-27 95.0 0.0 8.3e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal GerA PF03323.13 EMT54332.1 - 2.9e-190 632.7 3.5 3.3e-190 632.5 3.5 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein LGT PF01790.18 EMT54334.1 - 4.6e-77 258.5 16.4 5.2e-77 258.3 16.4 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase PHO4 PF01384.20 EMT54336.1 - 1.5e-87 293.8 42.4 5.3e-87 292.0 42.4 1.7 1 1 0 1 1 1 1 Phosphate transporter family Nbas_N PF15492.6 EMT54336.1 - 0.028 13.8 0.1 0.046 13.0 0.1 1.4 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal NADH_dh_m_C1 PF15088.6 EMT54336.1 - 0.43 10.2 1.2 18 5.1 0.1 2.4 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial PhoU_div PF01865.16 EMT54337.1 - 3e-33 115.0 7.3 3.3e-33 114.8 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 PhoU PF01895.19 EMT54337.1 - 0.014 15.9 4.4 0.088 13.3 0.9 2.3 2 0 0 2 2 2 0 PhoU domain Mating_N PF12731.7 EMT54337.1 - 0.033 14.3 0.0 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 Mating-type protein beta 1 Hormone_recep PF00104.30 EMT54337.1 - 0.072 12.7 0.7 0.19 11.3 0.2 1.8 1 1 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor RecG_N PF17190.4 EMT54337.1 - 0.11 13.3 5.5 1.4 9.7 0.2 3.2 1 1 1 3 3 3 0 RecG N-terminal helical domain Fib_alpha PF08702.10 EMT54337.1 - 0.37 11.0 3.8 4.2 7.5 0.3 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF167 PF02594.16 EMT54338.1 - 6.5e-10 39.0 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 DUF2992 PF11208.8 EMT54338.1 - 1e-07 32.3 0.0 1.4e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2992) DUF1904 PF08921.11 EMT54338.1 - 0.068 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) MarR_2 PF12802.7 EMT54339.1 - 4.8e-13 48.8 0.0 9e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EMT54339.1 - 3e-10 39.9 0.2 6.6e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 EMT54339.1 - 1.6e-06 28.5 0.0 2.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 EMT54339.1 - 0.00015 21.6 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 EMT54339.1 - 0.003 17.9 0.0 0.0033 17.8 0.0 1.2 1 0 0 1 1 1 1 Penicillinase repressor HTH_IclR PF09339.10 EMT54339.1 - 0.01 15.6 0.1 0.022 14.6 0.1 1.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_38 PF13936.6 EMT54339.1 - 0.092 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S13_N PF08069.12 EMT54339.1 - 0.12 12.4 0.0 0.9 9.6 0.0 2.3 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain MFS_1 PF07690.16 EMT54340.1 - 3.3e-54 184.1 47.0 3.7e-45 154.4 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT54340.1 - 9.1e-14 50.7 16.4 1.7e-13 49.8 16.4 1.4 1 1 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 EMT54340.1 - 2.1e-11 43.3 15.4 1.1e-09 37.7 4.5 2.1 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 EMT54340.1 - 3.7e-11 42.6 3.1 3.7e-11 42.6 3.1 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 EMT54340.1 - 0.00013 20.4 0.1 0.0072 14.7 0.0 2.5 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family UNC-93 PF05978.16 EMT54340.1 - 0.007 16.1 0.3 0.019 14.7 0.3 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Chal_sti_synt_N PF00195.19 EMT54341.1 - 5.2e-23 81.7 0.0 9.5e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 EMT54341.1 - 2e-20 73.3 0.0 3.4e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.12 EMT54341.1 - 5.7e-16 58.7 0.0 8.3e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 EMT54341.1 - 1.3e-09 38.0 0.0 3e-08 33.7 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EMT54341.1 - 8.9e-05 22.3 0.2 0.00023 21.0 0.2 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ICMT PF04140.14 EMT54342.1 - 1.8e-29 102.0 1.0 1.8e-29 102.0 1.0 1.8 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EMT54342.1 - 5.5e-07 29.9 0.8 1.1e-06 29.0 0.8 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 EMT54342.1 - 0.016 14.7 0.3 0.016 14.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Peptidase_M29 PF02073.15 EMT54344.1 - 1.7e-58 198.3 0.0 2e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) MarR PF01047.22 EMT54346.1 - 2.2e-13 49.9 0.2 3.9e-13 49.1 0.2 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EMT54346.1 - 8.5e-11 41.6 0.3 1.3e-10 40.9 0.3 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EMT54346.1 - 8.4e-10 39.0 0.1 1.4e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EMT54346.1 - 6.8e-06 25.5 0.0 1.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Penicillinase_R PF03965.16 EMT54346.1 - 0.00033 21.0 0.4 0.0012 19.1 0.4 1.9 1 1 0 1 1 1 1 Penicillinase repressor Replic_Relax PF13814.6 EMT54346.1 - 0.00069 19.7 0.1 0.0011 19.1 0.1 1.3 1 0 0 1 1 1 1 Replication-relaxation HTH_5 PF01022.20 EMT54346.1 - 0.00073 19.4 0.3 0.0023 17.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 EMT54346.1 - 0.0016 18.6 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_34 PF13601.6 EMT54346.1 - 0.002 18.3 0.2 0.0062 16.7 0.1 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.19 EMT54346.1 - 0.0049 16.7 0.1 0.0088 15.9 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 EMT54346.1 - 0.015 15.3 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Na_Pi_cotrans PF02690.15 EMT54346.1 - 0.18 11.9 0.1 0.38 10.9 0.0 1.5 2 0 0 2 2 2 0 Na+/Pi-cotransporter Peptidase_S24 PF00717.23 EMT54347.1 - 1.8e-16 59.8 0.1 4.8e-16 58.5 0.1 1.7 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 EMT54347.1 - 2e-14 53.6 0.0 3.3e-14 52.8 0.0 1.3 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 DUF4248 PF14053.6 EMT54348.1 - 0.00086 19.3 3.7 0.0039 17.2 0.2 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4248) PhoU_div PF01865.16 EMT54348.1 - 0.0089 15.4 1.6 0.011 15.1 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF47 START PF01852.19 EMT54348.1 - 0.015 14.7 0.3 0.02 14.3 0.3 1.2 1 0 0 1 1 1 0 START domain Spc7 PF08317.11 EMT54348.1 - 0.041 12.8 10.6 0.047 12.6 10.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Ntox28 PF15605.6 EMT54348.1 - 0.046 13.9 5.7 2.7 8.3 1.6 2.1 1 1 1 2 2 2 0 Bacterial toxin 28 HTH_50 PF18024.1 EMT54348.1 - 0.11 12.2 0.2 1.5 8.5 0.1 2.6 2 1 1 3 3 3 0 Helix-turn-helix domain Fib_alpha PF08702.10 EMT54348.1 - 0.11 12.7 13.8 0.12 12.6 13.8 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family KAsynt_C_assoc PF16197.5 EMT54348.1 - 0.17 12.4 1.2 0.25 11.8 0.9 1.5 1 1 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension DUF4446 PF14584.6 EMT54348.1 - 0.29 11.1 3.9 0.36 10.8 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) zf-RING_9 PF13901.6 EMT54348.1 - 0.36 10.8 6.6 0.47 10.4 6.6 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PPP1R35_C PF15503.6 EMT54348.1 - 0.37 10.6 7.4 0.79 9.5 0.3 2.3 1 1 1 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus RecQ_Zn_bind PF16124.5 EMT54348.1 - 1.9 9.3 7.3 29 5.5 7.3 2.4 1 1 0 1 1 1 0 RecQ zinc-binding Exonuc_VII_L PF02601.15 EMT54348.1 - 7.2 6.1 12.3 8 5.9 12.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit VanY PF02557.17 EMT54350.1 - 6.3e-45 152.2 0.0 9.2e-45 151.7 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Epimerase PF01370.21 EMT54351.1 - 1.4e-10 41.1 0.2 2.2e-08 33.8 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMT54351.1 - 0.0019 18.1 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_trans_4_2 PF13477.6 EMT54351.1 - 0.019 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like NAD_binding_4 PF07993.12 EMT54351.1 - 0.052 12.7 0.1 4.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein CbiJ PF02571.14 EMT54351.1 - 0.18 11.2 0.0 0.37 10.2 0.0 1.5 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK adh_short PF00106.25 EMT54351.1 - 0.19 11.1 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase G_glu_transpept PF01019.21 EMT54352.1 - 7.8e-172 572.6 0.1 9.3e-172 572.4 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cu_amine_oxidN1 PF07833.11 EMT54352.1 - 1.1e-05 25.8 0.0 3.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase N-terminal domain NAGPA PF09992.9 EMT54353.1 - 8.6e-38 130.2 0.3 1.3e-37 129.6 0.3 1.3 1 0 0 1 1 1 1 Phosphodiester glycosidase 7TMR-HDED PF07697.11 EMT54353.1 - 0.0083 16.3 1.6 0.012 15.7 1.6 1.2 1 0 0 1 1 1 1 7TM-HD extracellular CENP-Q PF13094.6 EMT54353.1 - 0.039 14.2 5.1 0.064 13.5 5.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SesA PF17107.5 EMT54353.1 - 0.07 13.3 1.0 0.12 12.6 1.0 1.3 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_13 PF13166.6 EMT54353.1 - 0.14 10.8 3.2 0.18 10.4 3.2 1.1 1 0 0 1 1 1 0 AAA domain Prominin PF05478.11 EMT54353.1 - 0.39 8.6 1.6 0.52 8.2 1.6 1.1 1 0 0 1 1 1 0 Prominin CorA PF01544.18 EMT54354.1 - 0.00026 20.4 0.2 0.00028 20.3 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF812 PF05667.11 EMT54354.1 - 0.00055 19.0 3.5 0.00061 18.8 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3584 PF12128.8 EMT54354.1 - 0.0021 15.7 7.8 0.0026 15.4 7.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TEX13 PF15186.6 EMT54354.1 - 0.004 16.9 6.1 0.0066 16.1 6.1 1.4 1 0 0 1 1 1 1 Testis-expressed sequence 13 protein family EzrA PF06160.12 EMT54354.1 - 0.0046 15.2 8.5 0.0054 15.0 8.5 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA YlqD PF11068.8 EMT54354.1 - 0.0064 16.9 14.1 0.19 12.1 7.9 2.2 2 0 0 2 2 2 1 YlqD protein Laminin_II PF06009.12 EMT54354.1 - 0.0067 16.4 6.3 0.0067 16.4 6.3 1.9 1 1 0 1 1 1 1 Laminin Domain II FapA PF03961.13 EMT54354.1 - 0.008 14.8 3.3 0.011 14.4 3.3 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 EMT54354.1 - 0.01 15.5 3.1 0.012 15.3 3.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HemX PF04375.14 EMT54354.1 - 0.012 14.9 10.6 0.018 14.4 10.6 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase KELK PF15796.5 EMT54354.1 - 0.014 15.9 6.2 0.014 15.9 6.2 1.9 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4200 PF13863.6 EMT54354.1 - 0.017 15.5 11.9 0.023 15.1 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Golgin_A5 PF09787.9 EMT54354.1 - 0.025 14.1 9.6 0.037 13.5 9.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1664 PF07889.12 EMT54354.1 - 0.025 14.6 12.7 0.12 12.4 11.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EMT54354.1 - 0.028 14.5 9.6 0.043 13.8 9.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 EMT54354.1 - 0.039 14.2 14.5 0.15 12.3 5.1 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ntox28 PF15605.6 EMT54354.1 - 0.039 14.2 2.7 0.093 13.0 2.7 1.8 1 1 0 1 1 1 0 Bacterial toxin 28 FH2 PF02181.23 EMT54354.1 - 0.04 13.0 6.2 0.064 12.4 6.2 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain CENP-F_leu_zip PF10473.9 EMT54354.1 - 0.053 13.6 10.4 0.083 12.9 10.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 EMT54354.1 - 0.058 13.4 1.5 0.058 13.4 1.5 3.2 1 1 2 3 3 3 0 FlxA-like protein Jnk-SapK_ap_N PF09744.9 EMT54354.1 - 0.071 13.3 9.8 0.11 12.7 9.8 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 NBP1 PF08537.10 EMT54354.1 - 0.075 12.4 7.7 0.15 11.4 7.7 1.5 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Prefoldin_2 PF01920.20 EMT54354.1 - 0.082 12.9 17.4 4.9 7.1 8.1 2.5 1 1 0 1 1 1 0 Prefoldin subunit DUF5320 PF17253.2 EMT54354.1 - 0.09 13.9 8.1 3 9.0 0.2 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5320) DUF4199 PF13858.6 EMT54354.1 - 0.11 12.9 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF724 PF05266.14 EMT54354.1 - 0.12 12.2 6.8 0.19 11.5 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) COG2 PF06148.11 EMT54354.1 - 0.14 12.2 6.4 0.2 11.8 5.8 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Cob_adeno_trans PF01923.18 EMT54354.1 - 0.17 12.0 3.6 0.32 11.1 3.6 1.5 1 1 0 1 1 1 0 Cobalamin adenosyltransferase IFT57 PF10498.9 EMT54354.1 - 0.17 10.8 9.3 0.22 10.4 9.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 WHEP-TRS PF00458.20 EMT54354.1 - 0.18 12.0 3.9 0.42 10.8 3.9 1.5 1 0 0 1 1 1 0 WHEP-TRS domain CHDCT2 PF08074.11 EMT54354.1 - 0.2 11.8 5.1 0.33 11.1 5.1 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain CEP63 PF17045.5 EMT54354.1 - 0.22 11.4 13.8 4.9 7.0 13.8 2.0 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa Syntaxin-6_N PF09177.11 EMT54354.1 - 0.22 12.1 4.7 1.1 9.9 4.7 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4665 PF15679.5 EMT54354.1 - 0.23 12.1 7.5 7.6 7.2 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) SlyX PF04102.12 EMT54354.1 - 0.27 11.9 20.4 0.12 13.1 2.1 2.5 1 1 1 2 2 2 0 SlyX HalX PF08663.10 EMT54354.1 - 0.28 11.5 2.0 0.45 10.9 0.1 2.1 2 1 0 2 2 2 0 HalX domain Allexi_40kDa PF05549.11 EMT54354.1 - 0.34 10.4 3.1 0.54 9.7 3.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Spc7 PF08317.11 EMT54354.1 - 0.42 9.4 11.8 0.59 9.0 11.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF745 PF05335.13 EMT54354.1 - 0.44 10.2 12.5 0.64 9.7 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ADIP PF11559.8 EMT54354.1 - 0.49 10.5 11.9 0.47 10.5 10.5 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 EMT54354.1 - 0.51 9.6 15.6 5.9 6.1 15.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 EMT54354.1 - 0.57 8.0 5.5 0.77 7.6 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ApoO PF09769.9 EMT54354.1 - 0.66 9.9 3.0 3.3 7.7 1.8 2.5 2 1 0 2 2 2 0 Apolipoprotein O NPV_P10 PF05531.12 EMT54354.1 - 0.67 10.5 14.7 3.9 8.0 1.3 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 EMT54354.1 - 0.76 9.0 8.7 1.1 8.5 8.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4140 PF13600.6 EMT54354.1 - 0.79 10.2 11.6 6.2 7.3 3.6 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF148 PF02520.17 EMT54354.1 - 1.2 9.3 12.4 12 6.1 12.1 2.1 1 1 0 1 1 1 0 Domain of unknown function DUF148 DUF4763 PF15960.5 EMT54354.1 - 1.2 8.4 12.0 1.9 7.7 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) YkyA PF10368.9 EMT54354.1 - 1.3 8.7 13.2 2.2 7.9 13.2 1.3 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF2408 PF10303.9 EMT54354.1 - 1.4 9.5 8.5 3.8 8.1 8.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Prominin PF05478.11 EMT54354.1 - 1.4 6.7 8.0 1.9 6.3 8.0 1.1 1 0 0 1 1 1 0 Prominin APG6_N PF17675.1 EMT54354.1 - 1.5 9.4 13.2 0.37 11.3 7.7 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region CCDC-167 PF15188.6 EMT54354.1 - 1.6 9.1 6.2 6.4 7.2 6.2 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Filament PF00038.21 EMT54354.1 - 1.7 8.1 13.8 1.8 8.1 10.2 1.9 1 1 1 2 2 2 0 Intermediate filament protein DASH_Dad2 PF08654.10 EMT54354.1 - 2 8.9 10.9 9.2 6.8 4.5 2.5 3 0 0 3 3 2 0 DASH complex subunit Dad2 DUF4407 PF14362.6 EMT54354.1 - 2.2 7.6 15.0 0.92 8.8 11.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DASH_Dam1 PF08653.10 EMT54354.1 - 2.3 8.1 3.8 12 5.7 0.3 2.6 1 1 2 3 3 3 0 DASH complex subunit Dam1 FliD_C PF07195.12 EMT54354.1 - 2.4 7.5 10.7 4.2 6.7 3.6 2.1 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Phage_GPO PF05929.11 EMT54354.1 - 2.7 7.5 10.3 2.1 7.9 5.0 1.7 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase bZIP_1 PF00170.21 EMT54354.1 - 2.8 8.1 9.7 2.7 8.1 1.1 2.6 2 1 0 2 2 2 0 bZIP transcription factor Mt_ATP-synt_D PF05873.12 EMT54354.1 - 2.9 7.7 7.8 11 5.9 4.4 2.1 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Prefoldin PF02996.17 EMT54354.1 - 3.5 7.6 15.6 0.72 9.8 1.8 3.0 2 1 0 2 2 2 0 Prefoldin subunit Rx_N PF18052.1 EMT54354.1 - 3.5 8.0 8.3 6 7.2 2.4 2.2 1 1 1 2 2 2 0 Rx N-terminal domain DUF1690 PF07956.11 EMT54354.1 - 3.6 8.0 10.2 6.7 7.1 10.2 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) THOC7 PF05615.13 EMT54354.1 - 4 7.7 11.9 23 5.3 11.9 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 Fmp27_WPPW PF10359.9 EMT54354.1 - 4.2 6.1 12.1 1.7 7.4 5.3 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain ATG16 PF08614.11 EMT54354.1 - 4.5 7.4 19.1 0.77 10.0 14.7 1.8 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 EMT54354.1 - 4.6 7.7 11.7 6.7 7.2 1.1 3.1 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) YabA PF06156.13 EMT54354.1 - 5.5 7.7 10.6 3.7e+02 1.8 10.7 2.7 1 1 0 1 1 1 0 Initiation control protein YabA PRKG1_interact PF15898.5 EMT54354.1 - 6.2 7.8 14.1 1.3e+03 0.3 14.1 2.3 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CdvA PF18822.1 EMT54354.1 - 6.4 6.6 11.7 12 5.7 0.7 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain MerR-DNA-bind PF09278.11 EMT54354.1 - 8.3 7.0 11.2 0.5 10.9 1.1 2.6 1 1 1 2 2 2 0 MerR, DNA binding UPF0242 PF06785.11 EMT54354.1 - 8.6 6.4 16.6 1.9e+02 2.0 16.7 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 EMT54354.1 - 8.8 6.9 15.4 17 6.0 12.8 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Sec20 PF03908.13 EMT54354.1 - 9.2 6.3 10.8 17 5.4 0.2 2.3 1 1 1 2 2 2 0 Sec20 RDD PF06271.12 EMT54355.1 - 7.9e-24 84.5 3.9 1.3e-23 83.8 3.9 1.3 1 0 0 1 1 1 1 RDD family DUF5493 PF17597.2 EMT54355.1 - 0.044 14.0 4.4 0.08 13.2 4.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5493) SpoIIM PF01944.17 EMT54356.1 - 8.7e-40 136.3 11.4 1.6e-39 135.5 11.4 1.4 1 0 0 1 1 1 1 Stage II sporulation protein M DUF58 PF01882.18 EMT54357.1 - 1.1e-21 76.8 0.0 3.2e-21 75.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function DUF58 VWA_2 PF13519.6 EMT54357.1 - 1.1e-06 29.3 0.0 2.7e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EMT54357.1 - 0.075 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain AAA_3 PF07726.11 EMT54358.1 - 8.1e-65 216.6 0.0 1.2e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EMT54358.1 - 4.8e-19 68.0 0.3 7.8e-19 67.3 0.3 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 EMT54358.1 - 1.3e-16 60.8 0.0 2.9e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMT54358.1 - 2.5e-06 27.0 0.8 0.0015 18.0 0.2 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EMT54358.1 - 7.6e-06 25.8 0.0 3.5e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 EMT54358.1 - 7.6e-06 25.2 0.0 3.7e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 EMT54358.1 - 3e-05 23.8 0.0 0.00014 21.6 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 EMT54358.1 - 3e-05 24.4 0.0 0.00017 22.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT54358.1 - 0.0002 21.8 0.0 0.00027 21.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EMT54358.1 - 0.037 14.6 0.0 0.2 12.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMT54358.1 - 0.059 13.1 0.1 0.18 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMT54358.1 - 0.084 13.2 0.1 1.9 8.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain Urm1 PF09138.11 EMT54358.1 - 0.094 13.1 0.1 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 Urm1 (Ubiquitin related modifier) AAA_22 PF13401.6 EMT54358.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMT54358.1 - 0.13 12.2 0.1 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EMT54358.1 - 0.19 11.7 0.5 0.44 10.6 0.1 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4350 PF14258.6 EMT54359.1 - 2.3e-11 44.0 0.0 6.2e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4350) Fumarate_red_C PF02300.17 EMT54359.1 - 0.022 14.8 1.5 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Fumarate reductase subunit C DUF4129 PF13559.6 EMT54360.1 - 8.1e-09 35.6 0.7 8.1e-09 35.6 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) DUF2561 PF10812.8 EMT54360.1 - 0.035 14.2 0.1 0.044 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) SRP54_N PF02881.19 EMT54360.1 - 0.049 13.8 0.1 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain AraC_N PF06719.13 EMT54360.1 - 0.14 11.8 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus DUF1664 PF07889.12 EMT54360.1 - 0.19 11.7 1.0 0.39 10.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3742 PF12553.8 EMT54360.1 - 1.6 8.8 5.3 8.1 6.6 5.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3742) GPDPase_memb PF10110.9 EMT54361.1 - 4.4e-06 25.7 31.8 5.4e-05 22.1 31.8 2.8 1 1 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase SPC25 PF06703.11 EMT54361.1 - 2.1 8.1 6.6 1.3 8.8 1.2 2.5 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Y_Y_Y PF07495.13 EMT54362.1 - 0.0024 17.8 0.7 0.067 13.2 0.0 2.8 2 0 0 2 2 2 1 Y_Y_Y domain C1q PF00386.21 EMT54362.1 - 0.022 15.0 0.3 0.14 12.3 0.0 2.4 2 1 1 3 3 3 0 C1q domain SoxZ PF08770.11 EMT54362.1 - 0.22 11.3 1.3 5.2 6.9 0.0 3.0 4 0 0 4 4 4 0 Sulphur oxidation protein SoxZ SlpA PF03217.14 EMT54362.1 - 0.68 10.6 5.8 19 6.0 0.1 3.6 4 0 0 4 4 4 0 Surface later protein A domain CBS PF00571.28 EMT54363.1 - 1.2e-20 73.7 0.9 4.7e-09 36.6 0.1 2.6 2 0 0 2 2 2 2 CBS domain GGDEF PF00990.21 EMT54363.1 - 2.7e-18 66.3 0.0 4.6e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Methyltransf_24 PF13578.6 EMT54363.1 - 0.021 15.8 0.0 0.62 11.1 0.0 2.6 1 1 0 2 2 2 0 Methyltransferase domain Ndr PF03096.14 EMT54364.1 - 0.026 13.2 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family EAL PF00563.20 EMT54365.1 - 9.3e-45 153.0 0.0 1e-44 152.8 0.0 1.0 1 0 0 1 1 1 1 EAL domain Peptidase_C39_2 PF13529.6 EMT54367.1 - 4.4e-37 127.8 0.0 5.8e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 EMT54367.1 - 0.00025 21.0 0.0 0.2 11.6 0.0 2.4 2 1 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 BtrH_N PF14399.6 EMT54367.1 - 0.0041 17.4 0.3 0.055 13.7 0.1 2.4 2 1 0 2 2 2 1 Butirosin biosynthesis protein H, N-terminal Peptidase_C39 PF03412.15 EMT54367.1 - 0.058 13.2 0.0 3.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase C39 family HTH_Tnp_Tc3_2 PF01498.18 EMT54367.1 - 0.085 13.1 0.1 6.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Transposase Guanylate_cyc_2 PF09778.9 EMT54367.1 - 0.2 11.0 0.0 0.52 9.6 0.0 1.6 2 0 0 2 2 2 0 Guanylylate cyclase YolD PF08863.10 EMT54368.1 - 1.6e-21 76.2 0.0 1.8e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 YolD-like protein Tudor_4 PF18358.1 EMT54368.1 - 0.033 13.8 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain IMS PF00817.20 EMT54370.1 - 5.7e-43 146.5 0.0 9.5e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EMT54370.1 - 1.9e-19 70.5 0.0 7.5e-19 68.6 0.0 2.0 2 1 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EMT54370.1 - 0.00024 21.2 0.0 0.00062 19.9 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.8 EMT54370.1 - 0.095 12.9 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 Pathogenicity locus Acetyltransf_1 PF00583.25 EMT54371.1 - 2.2e-10 40.8 0.1 2.8e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EMT54371.1 - 3.2e-08 34.3 0.1 4.3e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT54371.1 - 2.6e-05 24.4 0.0 3.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT54371.1 - 9.1e-05 22.4 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT54371.1 - 0.0001 22.6 0.0 0.00015 22.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMT54371.1 - 0.0024 17.6 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT54371.1 - 0.05 13.6 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Helicase_C PF00271.31 EMT54373.1 - 3.8e-25 88.4 0.0 1e-19 70.9 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecG_wedge PF17191.4 EMT54373.1 - 9.7e-20 70.8 0.0 1.9e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 RecG wedge domain DEAD PF00270.29 EMT54373.1 - 3.4e-18 66.0 0.2 7.1e-18 65.0 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EMT54373.1 - 6.7e-08 32.7 0.0 2.6e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Hemerythrin PF01814.23 EMT54373.1 - 0.015 15.9 0.0 0.073 13.7 0.0 2.1 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain SecA_DEAD PF07517.14 EMT54373.1 - 0.023 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain DUF1611_N PF17396.2 EMT54373.1 - 0.13 12.5 0.0 1.9 8.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1611_N) Rossmann-like domain SDH_alpha PF03313.15 EMT54374.1 - 3.4e-77 259.6 16.6 3.9e-77 259.4 16.6 1.0 1 0 0 1 1 1 1 Serine dehydratase alpha chain MmgE_PrpD PF03972.14 EMT54374.1 - 0.0056 15.3 9.2 0.0078 14.8 9.2 1.2 1 0 0 1 1 1 1 MmgE/PrpD family ATG_C PF09333.11 EMT54374.1 - 1.4 9.3 4.6 2.5 8.5 0.2 2.9 2 2 0 2 2 2 0 Autophagy-related protein C terminal domain SDH_beta PF03315.15 EMT54375.1 - 1.6e-15 57.8 0.2 2.2e-10 41.1 0.1 2.2 1 1 1 2 2 2 2 Serine dehydratase beta chain ACT PF01842.25 EMT54375.1 - 4.1e-11 42.4 0.1 1.3e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 EMT54375.1 - 0.00066 20.2 0.0 0.0014 19.2 0.0 1.5 1 0 0 1 1 1 1 ACT domain Gate PF07670.14 EMT54376.1 - 0.0067 16.7 15.3 0.5 10.6 6.0 3.2 2 2 0 2 2 2 2 Nucleoside recognition Amidohydro_1 PF01979.20 EMT54377.1 - 3.6e-09 36.4 0.0 1.9e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMT54377.1 - 5e-09 36.2 0.5 8.2e-08 32.1 0.0 2.3 2 1 0 2 2 2 1 Amidohydrolase family Acetyltransf_3 PF13302.7 EMT54378.1 - 2.1e-32 112.7 0.1 2.4e-32 112.5 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT54378.1 - 2.4e-09 37.4 0.1 3.4e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EMT54378.1 - 3.1e-05 24.2 0.0 3.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DegV PF02645.16 EMT54379.1 - 1.6e-83 280.3 1.5 1.7e-83 280.2 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 Prefoldin_3 PF13758.6 EMT54379.1 - 0.13 12.3 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit Dak1_2 PF13684.6 EMT54380.1 - 3.8e-121 404.0 1.3 3.8e-121 404.0 1.3 1.6 2 0 0 2 2 2 1 Dihydroxyacetone kinase family Dak2 PF02734.17 EMT54380.1 - 1.4e-42 145.6 1.2 2.2e-42 144.9 0.5 1.7 2 0 0 2 2 2 1 DAK2 domain DegV PF02645.16 EMT54380.1 - 0.00097 18.6 0.7 1.2 8.3 0.1 2.9 3 0 0 3 3 3 2 Uncharacterised protein, DegV family COG1307 Nitro_FeMo-Co PF02579.17 EMT54380.1 - 0.097 13.0 0.8 19 5.6 0.1 3.2 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor DUF3656 PF12392.8 EMT54380.1 - 0.1 13.3 0.0 0.41 11.3 0.0 2.0 1 1 1 2 2 2 0 Collagenase Asp23 PF03780.13 EMT54381.1 - 6e-35 119.9 5.2 6.8e-35 119.8 5.2 1.0 1 0 0 1 1 1 1 Asp23 family, cell envelope-related function Ribosomal_L28 PF00830.19 EMT54382.1 - 5.8e-18 64.8 3.6 6.7e-18 64.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L28 family SpoV PF08183.11 EMT54383.1 - 4.2e-17 61.8 1.7 4.6e-17 61.6 1.7 1.0 1 0 0 1 1 1 1 Stage V sporulation protein family Thia_YuaJ PF09515.10 EMT54384.1 - 1.3e-55 188.1 12.9 1.5e-55 187.9 12.9 1.0 1 0 0 1 1 1 1 Thiamine transporter protein (Thia_YuaJ) ECF-ribofla_trS PF07155.12 EMT54384.1 - 0.0014 18.6 11.7 0.002 18.2 11.7 1.1 1 0 0 1 1 1 1 ECF-type riboflavin transporter, S component DUF1691 PF07950.11 EMT54384.1 - 0.28 11.9 3.1 0.46 11.2 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1691) DUF4118 PF13493.6 EMT54384.1 - 1.2 8.9 14.5 0.04 13.7 6.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4118) ABC_tran PF00005.27 EMT54385.1 - 4.2e-38 130.9 0.0 5.7e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT54385.1 - 4.9e-11 43.0 0.0 0.00026 20.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT54385.1 - 1.3e-08 34.5 0.2 9.6e-07 28.5 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMT54385.1 - 1.2e-05 25.0 0.1 2.1e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EMT54385.1 - 6e-05 22.9 0.0 0.0043 16.8 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 EMT54385.1 - 0.00011 22.6 0.0 0.00016 22.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EMT54385.1 - 0.00043 20.9 0.1 0.00062 20.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMT54385.1 - 0.00082 19.7 0.1 0.002 18.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain RNA12 PF10443.9 EMT54385.1 - 0.0027 16.5 0.0 0.0038 16.0 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein AAA_30 PF13604.6 EMT54385.1 - 0.003 17.3 0.1 0.0064 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT54385.1 - 0.0033 17.4 0.1 0.0069 16.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_24 PF13479.6 EMT54385.1 - 0.0054 16.5 0.0 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 EMT54385.1 - 0.008 15.0 0.1 1.5 7.5 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class MeaB PF03308.16 EMT54385.1 - 0.0093 15.0 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_13 PF13166.6 EMT54385.1 - 0.0096 14.6 0.0 0.22 10.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMT54385.1 - 0.011 15.9 0.1 0.017 15.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EMT54385.1 - 0.03 14.5 0.3 0.35 11.1 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.15 EMT54385.1 - 0.036 12.9 0.1 0.31 9.8 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein T4SS-DNA_transf PF02534.14 EMT54385.1 - 0.045 12.6 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DUF87 PF01935.17 EMT54385.1 - 0.049 13.7 0.1 0.082 13.0 0.1 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain NACHT PF05729.12 EMT54385.1 - 0.05 13.5 0.1 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 EMT54385.1 - 0.068 12.7 0.1 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMT54385.1 - 0.076 13.3 0.4 0.24 11.7 0.1 2.0 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.20 EMT54385.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.23 EMT54385.1 - 0.095 12.8 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 EMT54385.1 - 0.1 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EMT54385.1 - 0.13 12.3 0.0 0.67 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EMT54385.1 - 0.13 11.6 0.0 4.1 6.8 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein ATPase_2 PF01637.18 EMT54385.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EMT54385.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain BPD_transp_1 PF00528.22 EMT54386.1 - 1.2e-22 80.6 11.5 1.2e-22 80.6 11.5 1.4 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component RuvB_C PF05491.13 EMT54386.1 - 0.027 14.3 0.1 0.065 13.1 0.1 1.6 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain TetR_N PF00440.23 EMT54386.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family SBP_bac_3 PF00497.20 EMT54387.1 - 4.7e-59 199.5 1.8 5.5e-59 199.3 1.8 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EMT54387.1 - 8.1e-09 35.7 0.1 1.2e-07 31.9 0.1 2.4 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Phosphonate-bd PF12974.7 EMT54387.1 - 3.1e-07 30.2 0.2 9.2e-07 28.7 0.2 1.7 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EMT54387.1 - 2.4e-06 27.7 1.4 0.00016 21.7 0.4 2.2 1 1 1 2 2 2 2 NMT1/THI5 like LPAM_1 PF08139.12 EMT54387.1 - 0.69 10.5 4.4 2.1 9.0 4.4 1.8 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Peptidase_M20 PF01546.28 EMT54388.1 - 1.6e-26 93.3 0.2 2.2e-26 92.8 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT54388.1 - 2.6e-19 69.1 0.3 2.6e-19 69.1 0.3 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMT54388.1 - 5.1e-07 29.6 0.0 1.2e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 RDD PF06271.12 EMT54389.1 - 2e-21 76.7 8.8 7.1e-21 74.9 8.8 1.7 1 1 0 1 1 1 1 RDD family DUF4310 PF14187.6 EMT54389.1 - 0.0091 15.7 6.4 0.013 15.2 6.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4310) Ribul_P_3_epim PF00834.19 EMT54390.1 - 2.8e-90 301.0 0.0 3.2e-90 300.8 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family DUF3237 PF11578.8 EMT54390.1 - 0.003 17.4 0.0 0.73 9.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) LRV PF01816.17 EMT54390.1 - 0.077 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Leucine rich repeat variant RsgA_GTPase PF03193.16 EMT54391.1 - 7.1e-62 208.2 0.0 1e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase RsgA_N PF16745.5 EMT54391.1 - 2.5e-23 81.6 0.7 7.9e-23 80.0 0.3 2.0 2 0 0 2 2 2 1 RsgA N-terminal domain MMR_HSR1 PF01926.23 EMT54391.1 - 1.3e-08 34.9 0.0 2.8e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMT54391.1 - 8.4e-05 22.1 0.2 0.23 11.0 0.0 2.5 2 1 0 2 2 2 2 Ferrous iron transport protein B ABC_tran PF00005.27 EMT54391.1 - 0.002 18.6 0.0 0.0056 17.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter MMR_HSR1_Xtn PF16897.5 EMT54391.1 - 0.0078 16.2 0.1 0.017 15.1 0.0 1.6 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain AAA_29 PF13555.6 EMT54391.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EMT54391.1 - 0.037 14.4 0.0 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EMT54391.1 - 0.048 12.9 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_23 PF13476.6 EMT54391.1 - 0.077 13.5 1.1 0.15 12.5 0.1 1.8 1 1 1 2 2 2 0 AAA domain IIGP PF05049.13 EMT54391.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Pkinase PF00069.25 EMT54392.1 - 5.9e-57 193.0 0.0 8.4e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMT54392.1 - 1.5e-40 139.1 0.0 2.2e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PASTA PF03793.19 EMT54392.1 - 1.6e-27 95.1 10.6 6e-10 38.8 1.1 3.8 3 0 0 3 3 3 3 PASTA domain APH PF01636.23 EMT54392.1 - 6e-07 29.6 0.6 0.0007 19.6 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EMT54392.1 - 7.9e-05 22.1 0.0 0.00036 20.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EMT54392.1 - 0.00014 21.5 0.2 0.0012 18.4 0.1 2.2 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EMT54392.1 - 0.017 14.4 0.4 0.03 13.7 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EMT54392.1 - 0.035 13.1 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EMT54392.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PP2C_2 PF13672.6 EMT54393.1 - 2.3e-20 73.1 0.4 3.3e-20 72.6 0.4 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EMT54393.1 - 2.6e-11 43.7 0.1 8.7e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EMT54393.1 - 1.1e-09 38.6 2.8 7.9e-09 35.7 2.8 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Radical_SAM PF04055.21 EMT54394.1 - 5.9e-18 65.8 0.0 1e-17 65.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EMT54394.1 - 3e-05 24.2 0.0 7.8e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 EMT54394.1 - 0.028 14.7 0.0 0.077 13.3 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF4252 PF14060.6 EMT54394.1 - 0.054 13.4 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Methyltr_RsmB-F PF01189.17 EMT54395.1 - 1.9e-62 210.4 0.0 2.8e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 EMT54395.1 - 3.4e-29 101.8 0.2 6.2e-29 100.9 0.2 1.4 1 0 0 1 1 1 1 NusB family Methyltr_RsmF_N PF17125.5 EMT54395.1 - 2.4e-07 31.1 0.0 4.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_31 PF13847.6 EMT54395.1 - 1.8e-06 27.8 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EMT54395.1 - 1.8e-05 24.9 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EMT54395.1 - 0.00078 20.1 0.0 0.0053 17.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMT54395.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF2431 PF10354.9 EMT54395.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) TRM PF02005.16 EMT54395.1 - 0.031 13.5 0.0 0.07 12.3 0.0 1.5 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Fibrillarin PF01269.17 EMT54395.1 - 0.045 12.9 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin PCMT PF01135.19 EMT54395.1 - 0.2 11.4 0.0 0.45 10.2 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Formyl_trans_N PF00551.19 EMT54396.1 - 6.5e-41 140.1 0.0 1.5e-40 138.9 0.0 1.5 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.18 EMT54396.1 - 2.1e-32 111.4 0.1 3.2e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Glyco_trans_4_4 PF13579.6 EMT54396.1 - 0.085 13.3 0.2 0.14 12.6 0.2 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Pep_deformylase PF01327.21 EMT54397.1 - 3.3e-52 176.3 0.0 4e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase DUF43 PF01861.16 EMT54397.1 - 0.04 13.1 0.2 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain PriA_3primeBD PF17764.1 EMT54398.1 - 1.3e-28 98.8 0.0 3e-28 97.6 0.0 1.7 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) PriA_C PF18074.1 EMT54398.1 - 7e-23 81.3 0.1 2.6e-22 79.4 0.1 2.1 1 0 0 1 1 1 1 Primosomal protein N C-terminal domain ResIII PF04851.15 EMT54398.1 - 2.8e-17 63.3 0.0 4.9e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMT54398.1 - 1.2e-15 57.7 0.0 2.7e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMT54398.1 - 8.5e-13 48.6 0.0 2.4e-08 34.3 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain PriA_CRR PF18319.1 EMT54398.1 - 6.9e-10 38.7 9.9 6.9e-10 38.7 9.9 2.5 3 0 0 3 3 2 1 PriA DNA helicase Cys-rich region (CRR) domain AAA_16 PF13191.6 EMT54398.1 - 0.0097 16.3 2.3 0.02 15.3 0.2 2.7 3 1 0 3 3 2 1 AAA ATPase domain HTH_11 PF08279.12 EMT54398.1 - 0.02 14.8 0.2 0.049 13.6 0.2 1.7 1 0 0 1 1 1 0 HTH domain TrwB_AAD_bind PF10412.9 EMT54398.1 - 0.028 13.3 0.1 0.085 11.8 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 EMT54398.1 - 0.034 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.14 EMT54398.1 - 0.036 13.2 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AbiEi_4 PF13338.6 EMT54398.1 - 0.052 13.7 1.3 0.79 9.9 0.0 3.2 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin DUF2075 PF09848.9 EMT54398.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) zinc-ribbons_6 PF07191.12 EMT54398.1 - 0.086 12.8 7.2 0.2 11.7 7.2 1.6 1 0 0 1 1 1 0 zinc-ribbons AAA_33 PF13671.6 EMT54398.1 - 0.086 13.0 0.1 21 5.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EMT54398.1 - 0.095 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EMT54398.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain HypA PF01155.19 EMT54398.1 - 0.16 12.0 8.2 1.3 9.1 8.2 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EMT54398.1 - 7 6.8 13.3 1.6e+02 2.4 13.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon DFP PF04127.15 EMT54399.1 - 6.9e-76 254.2 0.7 2.3e-75 252.5 0.1 2.0 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 EMT54399.1 - 1.4e-46 158.2 0.2 2.4e-46 157.4 0.2 1.4 1 0 0 1 1 1 1 Flavoprotein Glyco_trans_4_4 PF13579.6 EMT54399.1 - 0.0073 16.8 0.1 0.056 13.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain DUF1485 PF07364.12 EMT54399.1 - 0.025 13.9 0.3 0.052 12.8 0.3 1.5 1 0 0 1 1 1 0 Metallopeptidase family M81 adh_short_C2 PF13561.6 EMT54399.1 - 1.8 8.1 6.0 3.7 7.1 0.7 3.5 4 2 0 4 4 4 0 Enoyl-(Acyl carrier protein) reductase RNA_pol_Rpb6 PF01192.22 EMT54400.1 - 8.4e-14 51.2 0.8 1e-13 51.0 0.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF1609 PF07753.11 EMT54400.1 - 0.045 13.3 0.2 0.046 13.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) Multi_ubiq PF14452.6 EMT54400.1 - 0.088 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Multiubiquitin Guanylate_kin PF00625.21 EMT54401.1 - 4.5e-50 169.8 0.0 5.3e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 EMT54401.1 - 2.6e-06 28.0 0.0 4.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMT54401.1 - 0.00039 20.6 0.0 0.0026 17.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EMT54401.1 - 0.0015 19.0 0.1 0.0091 16.4 0.0 2.2 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 EMT54401.1 - 0.003 18.0 0.0 0.0055 17.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMT54401.1 - 0.0052 17.1 0.0 0.0095 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMT54401.1 - 0.0056 16.6 0.1 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase Thymidylate_kin PF02223.17 EMT54401.1 - 0.0073 16.0 0.1 0.35 10.5 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase AAA PF00004.29 EMT54401.1 - 0.0073 16.7 0.1 0.02 15.3 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EMT54401.1 - 0.01 16.4 0.2 0.12 12.9 0.2 2.2 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.15 EMT54401.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 EMT54401.1 - 0.031 14.4 0.0 0.07 13.2 0.0 1.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 EMT54401.1 - 0.032 14.0 0.4 0.065 13.0 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 EMT54401.1 - 0.036 14.3 0.4 0.22 11.7 0.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMT54401.1 - 0.037 13.7 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 EMT54401.1 - 0.044 13.9 0.1 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase DUF370 PF04025.12 EMT54402.1 - 2.5e-38 130.0 1.3 2.9e-38 129.8 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF370) RII_binding_1 PF10522.9 EMT54402.1 - 0.2 11.9 2.3 33 5.1 0.1 3.9 4 0 0 4 4 4 0 RII binding domain YicC_N PF03755.13 EMT54403.1 - 2.3e-39 135.3 0.4 2.3e-39 135.3 0.4 2.1 2 1 0 2 2 2 1 YicC-like family, N-terminal region DUF1732 PF08340.11 EMT54403.1 - 2.7e-38 129.8 4.2 2.7e-38 129.8 4.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1732) CorA PF01544.18 EMT54403.1 - 1.5 8.1 5.7 1 8.6 0.1 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF2512 PF10710.9 EMT54404.1 - 9.1e-25 86.9 4.9 9.8e-25 86.8 4.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2512) Nmad4 PF18756.1 EMT54405.1 - 0.039 14.3 0.0 0.057 13.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotide modification associated domain 4 SpoIIIAH PF12685.7 EMT54405.1 - 0.083 12.7 1.9 0.11 12.3 1.9 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein ECH_1 PF00378.20 EMT54406.1 - 2.5e-49 167.9 0.5 2.9e-49 167.7 0.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMT54406.1 - 2.9e-35 122.4 1.2 2.5e-34 119.3 0.4 1.8 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Antimicrobial_4 PF08024.11 EMT54406.1 - 0.022 14.8 0.0 0.073 13.1 0.0 2.0 1 0 0 1 1 1 0 Ant antimicrobial peptide CoA_transf_3 PF02515.17 EMT54407.1 - 1.3e-98 330.5 0.0 1.5e-98 330.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III EamA PF00892.20 EMT54408.1 - 1.1e-46 158.4 30.9 2.7e-23 82.6 13.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EMT54408.1 - 1.4e-10 41.1 10.1 2.1e-10 40.5 10.1 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 EMT54408.1 - 2.7e-06 26.6 3.0 9.1e-06 24.8 1.3 2.1 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like DUF4748 PF15932.5 EMT54408.1 - 0.0053 16.5 0.0 0.021 14.5 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) Mg_trans_NIPA PF05653.14 EMT54408.1 - 0.016 14.4 0.6 0.016 14.4 0.6 2.4 2 1 0 2 2 2 0 Magnesium transporter NIPA EptA_B_N PF08019.12 EMT54408.1 - 0.052 13.4 0.4 0.052 13.4 0.4 3.0 2 1 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB Nuc_sug_transp PF04142.15 EMT54408.1 - 0.39 9.9 6.4 0.41 9.8 0.8 3.0 3 1 1 4 4 4 0 Nucleotide-sugar transporter GntR PF00392.21 EMT54409.1 - 2.6e-19 68.6 0.2 4.6e-19 67.8 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 EMT54409.1 - 4.6e-05 23.7 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator HTH_29 PF13551.6 EMT54409.1 - 0.0039 17.2 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix TrmB PF01978.19 EMT54409.1 - 0.012 15.5 0.5 0.05 13.5 0.1 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 EMT54409.1 - 0.015 15.2 0.2 0.25 11.4 0.0 2.6 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain HTH_28 PF13518.6 EMT54409.1 - 0.038 14.1 0.1 0.084 13.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 EMT54409.1 - 0.055 13.3 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 TFIIE alpha subunit HTH_23 PF13384.6 EMT54409.1 - 0.13 12.1 0.0 0.39 10.6 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain YjzC PF14168.6 EMT54410.1 - 2.2e-24 85.6 0.3 2.4e-24 85.4 0.3 1.0 1 0 0 1 1 1 1 YjzC-like protein DUF5615 PF18480.1 EMT54411.1 - 0.0093 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) PglD_N PF17836.1 EMT54411.1 - 0.057 14.1 0.5 0.81 10.4 0.0 2.0 1 1 1 2 2 2 0 PglD N-terminal domain DUF309 PF03745.14 EMT54412.1 - 2e-23 81.8 0.6 3.2e-23 81.2 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF309) TPR_14 PF13428.6 EMT54412.1 - 0.11 13.4 0.0 3.7 8.6 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat FIST_C PF10442.9 EMT54412.1 - 0.16 12.0 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 FIST C domain PTS_2-RNA PF01885.16 EMT54413.1 - 2.6e-15 56.9 0.0 3.8e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF1601 PF07671.11 EMT54413.1 - 0.022 14.6 0.8 0.041 13.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) CPBP PF02517.16 EMT54414.1 - 3.1e-09 37.1 12.0 3.1e-09 37.1 12.0 2.7 2 2 0 2 2 2 1 CPBP intramembrane metalloprotease CYYR1 PF10873.8 EMT54414.1 - 2.2 8.7 4.8 0.4 11.1 0.5 1.8 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 MFS_1 PF07690.16 EMT54415.1 - 1.2e-21 77.0 36.7 3e-14 52.7 12.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT54415.1 - 1.4e-14 53.4 16.4 1.7e-14 53.1 16.4 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 EMT54415.1 - 8.4e-08 31.2 29.1 0.00076 18.1 8.6 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein DUF1453 PF07301.11 EMT54416.1 - 1.1e-50 171.4 14.2 1.3e-50 171.2 14.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1453) Na_Ca_ex PF01699.24 EMT54416.1 - 0.38 10.7 8.2 0.21 11.6 6.5 1.4 1 1 0 1 1 1 0 Sodium/calcium exchanger protein Glyoxalase_3 PF13468.6 EMT54417.1 - 2e-39 135.5 0.2 4.4e-39 134.4 0.2 1.5 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EMT54417.1 - 7.3e-05 23.0 0.0 0.049 13.9 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 EMT54417.1 - 0.00056 20.1 0.0 0.014 15.6 0.0 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DAO PF01266.24 EMT54418.1 - 1.4e-54 186.0 0.2 2e-54 185.5 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EMT54418.1 - 2.5e-19 69.4 0.6 5.3e-19 68.3 0.2 1.8 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_3 PF01494.19 EMT54418.1 - 2.5e-07 30.3 0.1 7.8e-07 28.7 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EMT54418.1 - 0.00081 18.6 0.7 0.031 13.4 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EMT54418.1 - 0.0022 17.3 0.5 0.016 14.5 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMT54418.1 - 0.0045 17.2 3.2 0.011 15.9 0.9 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMT54418.1 - 0.0064 15.9 0.4 0.023 14.1 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EMT54418.1 - 0.015 14.4 0.1 0.079 12.0 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EMT54418.1 - 0.09 13.3 0.3 0.36 11.4 0.3 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EMT54418.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain G3P_antiterm PF04309.12 EMT54419.1 - 1.2e-64 216.9 0.4 1.4e-64 216.7 0.4 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 EMT54419.1 - 7.6e-06 25.5 3.9 8.9e-05 22.0 3.9 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 EMT54419.1 - 0.0019 17.7 0.3 0.018 14.5 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.21 EMT54419.1 - 0.0071 15.6 0.1 0.0085 15.3 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase IMPDH PF00478.25 EMT54419.1 - 0.1 11.6 0.2 0.2 10.6 0.1 1.4 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Hydrolase_6 PF13344.6 EMT54420.1 - 2e-28 98.5 0.0 3.7e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMT54420.1 - 8.4e-25 86.6 0.1 2.8e-22 78.5 0.0 2.6 3 0 0 3 3 3 2 HAD-hyrolase-like Hydrolase PF00702.26 EMT54420.1 - 2e-12 47.9 1.9 1.3e-10 42.0 1.9 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMT54420.1 - 2.5e-08 34.2 2.6 7.7e-05 22.8 0.0 3.4 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EMT54420.1 - 0.00033 20.3 0.0 0.0088 15.7 0.0 2.8 2 1 1 3 3 3 1 Mitochondrial PGP phosphatase Hydrolase_3 PF08282.12 EMT54420.1 - 0.0016 18.2 0.3 0.0034 17.2 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMT54420.1 - 0.0021 18.5 0.9 8 6.8 0.0 3.1 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EMT54420.1 - 0.0075 15.9 0.0 0.017 14.7 0.0 1.6 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) BPD_transp_1 PF00528.22 EMT54421.1 - 2e-22 79.8 52.9 9.2e-16 58.1 22.0 4.2 2 2 2 4 4 4 2 Binding-protein-dependent transport system inner membrane component PgaD PF13994.6 EMT54421.1 - 7.1 6.7 7.1 1.2 9.2 0.7 2.5 2 0 0 2 2 2 0 PgaD-like protein ABC_tran PF00005.27 EMT54422.1 - 1e-33 116.7 0.0 1.9e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 EMT54422.1 - 6.4e-12 45.5 0.0 5e-11 42.6 0.0 2.4 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 EMT54422.1 - 3.8e-07 30.2 0.0 0.00048 20.0 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT54422.1 - 0.00091 18.7 0.1 0.053 12.9 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMT54422.1 - 0.0045 17.5 0.0 0.0096 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EMT54422.1 - 0.0062 17.0 0.2 0.097 13.1 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EMT54422.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TOBE PF03459.17 EMT54422.1 - 0.016 15.5 0.0 2.2 8.6 0.0 3.2 1 1 1 2 2 2 0 TOBE domain AAA_16 PF13191.6 EMT54422.1 - 0.018 15.5 0.0 0.037 14.4 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 EMT54422.1 - 0.026 13.9 0.5 1.6 8.0 0.1 2.2 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 EMT54422.1 - 0.035 14.4 0.3 0.097 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMT54422.1 - 0.046 13.3 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain SBP_bac_6 PF13343.6 EMT54423.1 - 1.2e-37 129.7 2.1 1.6e-37 129.2 2.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EMT54423.1 - 4.1e-24 85.9 5.3 5.4e-24 85.5 5.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT54423.1 - 1.1e-20 74.9 10.2 1.5e-20 74.4 10.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EMT54423.1 - 2.2e-18 66.9 0.0 6.6e-15 55.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein Phosphonate-bd PF12974.7 EMT54423.1 - 0.00034 20.3 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein TrbI PF03743.14 EMT54423.1 - 0.17 11.7 0.5 0.28 11.0 0.5 1.4 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein FGGY_N PF00370.21 EMT54424.1 - 5.8e-83 278.2 0.0 7.6e-83 277.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EMT54424.1 - 4e-64 216.0 0.6 6.8e-64 215.2 0.6 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EMT54424.1 - 0.0038 16.8 0.1 0.012 15.1 0.0 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Homoserine_dh PF00742.19 EMT54425.1 - 1.8e-58 197.3 0.0 2.6e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EMT54425.1 - 6.6e-20 71.9 0.7 1.6e-19 70.6 0.7 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF1611_N PF17396.2 EMT54425.1 - 0.025 14.8 0.1 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain Sacchrp_dh_NADP PF03435.18 EMT54425.1 - 0.043 14.1 0.1 0.087 13.1 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ATP1G1_PLM_MAT8 PF02038.16 EMT54425.1 - 0.15 11.5 0.1 4.9 6.7 0.0 2.4 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family SecA_DEAD PF07517.14 EMT54425.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain Sacchrp_dh_C PF16653.5 EMT54426.1 - 1.8e-24 87.3 0.0 2.3e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EMT54426.1 - 1.7e-16 60.7 0.1 4.1e-16 59.4 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 EMT54426.1 - 0.00012 22.2 0.2 0.0002 21.5 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EMT54426.1 - 0.13 13.1 0.0 0.25 12.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold SBP_bac_8 PF13416.6 EMT54427.1 - 1.8e-31 110.0 0.1 2.2e-31 109.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EMT54427.1 - 1.3e-24 87.0 0.1 1.9e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EMT54427.1 - 2.2e-15 57.5 0.6 1.5e-14 54.7 0.6 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EMT54427.1 - 2.4e-14 53.7 0.0 3.8e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 EMT54427.1 - 3.8e-07 29.2 0.2 0.00011 21.1 0.2 2.9 2 1 0 2 2 2 2 Hypothetical lipoprotein (MG045 family) LPAM_2 PF13627.6 EMT54427.1 - 2.6 8.0 6.1 5.3 7.0 6.1 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Amidohydro_3 PF07969.11 EMT54428.1 - 3.3e-92 310.4 0.0 4.4e-92 310.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EMT54428.1 - 2.7e-09 36.8 0.0 2.3e-05 23.9 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family DAP_epimerase PF01678.19 EMT54429.1 - 8.9e-45 151.8 0.2 1.3e-24 86.7 0.1 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase SDF PF00375.18 EMT54430.1 - 2.3e-95 319.9 30.3 2.8e-95 319.6 30.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family 60KD_IMP PF02096.20 EMT54430.1 - 4.6 7.1 7.6 4.9 7.0 0.3 3.1 2 1 0 2 2 2 0 60Kd inner membrane protein Trp_dioxygenase PF03301.13 EMT54431.1 - 3.7e-22 79.1 0.1 1.3e-14 54.3 0.1 2.0 2 0 0 2 2 2 2 Tryptophan 2,3-dioxygenase Hs1pro-1_C PF07014.12 EMT54431.1 - 0.0036 16.8 0.0 0.044 13.2 0.0 2.0 2 0 0 2 2 2 1 Hs1pro-1 protein C-terminus YfdX PF10938.8 EMT54431.1 - 0.075 13.0 0.0 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 YfdX protein Cyclase PF04199.13 EMT54432.1 - 8.3e-25 87.6 0.0 1.1e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Aminotran_5 PF00266.19 EMT54433.1 - 1.7e-21 76.6 0.0 2e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EMT54433.1 - 0.077 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 EMT54433.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III TetR_N PF00440.23 EMT54434.1 - 2.5e-14 52.8 1.6 1.6e-13 50.2 0.3 2.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family PheRS_DBD3 PF18553.1 EMT54434.1 - 0.12 12.7 0.1 16 5.8 0.0 2.9 3 0 0 3 3 3 0 PheRS DNA binding domain 3 DUF218 PF02698.17 EMT54435.1 - 1e-28 100.0 0.0 1.3e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain TPR_2 PF07719.17 EMT54436.1 - 6.2e-19 66.5 15.2 1.8e-06 27.6 0.4 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMT54436.1 - 4.3e-13 49.6 5.1 0.00015 22.2 0.8 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EMT54436.1 - 2.3e-12 47.3 5.6 0.0013 19.3 0.4 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EMT54436.1 - 5.4e-12 45.0 12.1 7.4e-05 22.4 0.4 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMT54436.1 - 1.7e-10 40.3 9.2 0.0015 18.5 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMT54436.1 - 2.8e-08 33.9 7.4 0.012 15.8 0.7 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMT54436.1 - 3.2e-08 33.7 8.6 0.0071 17.1 0.1 4.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMT54436.1 - 2.3e-07 30.4 3.7 0.019 15.0 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMT54436.1 - 6.8e-05 23.0 3.8 0.00077 19.6 0.1 2.7 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EMT54436.1 - 0.00016 22.0 2.4 0.62 10.9 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EMT54436.1 - 0.00061 19.1 2.3 0.14 11.3 0.0 3.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EMT54436.1 - 0.0022 17.8 11.8 0.52 10.3 0.9 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMT54436.1 - 0.0092 15.6 0.5 0.0092 15.6 0.5 3.2 3 0 0 3 3 3 1 TPR repeat TPR_20 PF14561.6 EMT54436.1 - 0.018 15.3 0.8 5.8 7.3 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EMT54436.1 - 0.04 14.0 8.0 1.1 9.4 0.1 4.2 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EMT54436.1 - 0.05 14.3 8.3 0.29 11.9 0.4 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMT54436.1 - 0.054 13.6 5.7 13 5.9 0.0 3.9 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EMT54436.1 - 0.075 13.2 3.3 4.6 7.5 0.2 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat HDOD PF08668.12 EMT54436.1 - 0.26 10.8 0.3 0.51 9.8 0.3 1.5 1 1 0 1 1 1 0 HDOD domain TPR_17 PF13431.6 EMT54436.1 - 0.32 11.5 8.1 1.6 9.3 0.1 4.9 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 EMT54436.1 - 0.37 10.9 13.2 3.1 7.9 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ABC2_membrane_5 PF13346.6 EMT54437.1 - 0.084 12.4 2.7 0.1 12.1 2.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Oxidored_q2 PF00420.24 EMT54437.1 - 0.1 12.2 1.2 0.22 11.2 1.2 1.6 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF1129 PF06570.11 EMT54437.1 - 0.14 11.6 1.6 0.2 11.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF1453 PF07301.11 EMT54437.1 - 0.46 10.5 5.1 1.4 8.9 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) Nitroreductase PF00881.24 EMT54438.1 - 1.3e-28 100.2 0.3 3.7e-28 98.7 0.3 1.7 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EMT54438.1 - 0.00077 19.1 0.0 0.024 14.2 0.1 2.6 2 1 0 2 2 2 1 Putative TM nitroreductase DUF4644 PF15486.6 EMT54438.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) Pribosyltran PF00156.27 EMT54439.1 - 5.4e-17 61.8 0.1 8.4e-17 61.1 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 EMT54439.1 - 0.11 12.0 0.0 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl transferase OMPdecase PF00215.24 EMT54440.1 - 3.2e-45 154.4 0.1 3.6e-45 154.3 0.1 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DEDD_Tnp_IS110 PF01548.17 EMT54440.1 - 0.054 13.4 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Transposase CPSase_L_D2 PF02786.17 EMT54441.1 - 1.3e-122 407.1 0.3 3.6e-84 281.5 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EMT54441.1 - 4.6e-42 143.2 0.1 1.3e-41 141.7 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATPgrasp_Ter PF15632.6 EMT54441.1 - 3.7e-18 65.5 0.0 6.9e-11 42.0 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 EMT54441.1 - 5.3e-18 65.3 0.1 2.5e-09 36.9 0.0 2.9 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus MGS PF02142.22 EMT54441.1 - 8.3e-18 64.4 0.2 2.5e-16 59.7 0.0 3.6 4 0 0 4 4 4 1 MGS-like domain ATP-grasp_3 PF02655.14 EMT54441.1 - 3e-17 63.1 0.6 1.6e-10 41.3 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp PF02222.22 EMT54441.1 - 1.1e-14 54.4 0.0 2.5e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 EMT54441.1 - 3.3e-13 49.8 0.1 1.1e-08 35.1 0.1 2.8 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 EMT54441.1 - 2.8e-06 27.0 0.1 0.07 12.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 EMT54441.1 - 7.9e-05 22.3 0.2 0.0052 16.4 0.0 3.1 3 1 0 3 3 3 1 ATP-grasp domain NBD_C PF17042.5 EMT54441.1 - 0.0065 17.0 0.1 1.4 9.4 0.0 2.7 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain CoA_binding_2 PF13380.6 EMT54441.1 - 0.0091 16.5 0.0 1.5 9.3 0.0 3.8 3 1 0 3 3 3 1 CoA binding domain ATP-grasp_2 PF08442.10 EMT54441.1 - 0.0093 15.5 0.0 5.3 6.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peripla_BP_6 PF13458.6 EMT54441.1 - 0.041 13.6 0.3 11 5.5 0.0 2.7 3 0 0 3 3 3 0 Periplasmic binding protein CPSase_sm_chain PF00988.22 EMT54442.1 - 9.2e-53 177.5 0.0 1.5e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EMT54442.1 - 4.1e-48 163.7 0.0 5.7e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EMT54442.1 - 4.1e-09 36.5 0.1 9e-07 28.9 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 Amidohydro_1 PF01979.20 EMT54443.1 - 1.1e-48 166.3 0.0 1.8e-48 165.7 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family DHOase PF12890.7 EMT54443.1 - 9.3e-30 103.4 0.0 1.5e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Dihydro-orotase-like Amidohydro_3 PF07969.11 EMT54443.1 - 1.8e-13 50.8 1.4 2.4e-07 30.6 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family OTCace_N PF02729.21 EMT54444.1 - 1e-39 135.9 0.0 1.5e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EMT54444.1 - 5.1e-22 78.6 0.1 1.4e-21 77.2 0.1 1.8 1 1 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Xan_ur_permease PF00860.20 EMT54445.1 - 1.1e-94 317.4 39.1 1.4e-94 317.0 39.1 1.1 1 0 0 1 1 1 1 Permease family Pribosyltran PF00156.27 EMT54446.1 - 8.4e-22 77.4 0.6 9.4e-22 77.2 0.6 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EMT54446.1 - 1e-06 28.4 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EMT54446.1 - 0.00018 21.1 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase PD40 PF07676.12 EMT54447.1 - 3.2e-17 62.0 6.6 0.016 15.1 0.0 6.5 7 0 0 7 7 7 5 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EMT54447.1 - 1.7e-06 27.1 0.6 0.099 11.4 0.0 4.7 5 0 0 5 5 5 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region ANAPC4_WD40 PF12894.7 EMT54447.1 - 7.2e-05 23.0 0.0 0.023 15.0 0.0 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMT54447.1 - 0.0021 18.0 0.0 4.8 7.0 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Glyoxalase PF00903.25 EMT54448.1 - 9.4e-12 45.2 0.2 2.7e-11 43.7 0.2 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EMT54448.1 - 3.1e-08 33.9 0.1 3.8e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EMT54448.1 - 2.3e-05 24.6 0.3 3.6e-05 24.0 0.3 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EMT54448.1 - 0.00041 21.1 0.1 0.00081 20.2 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EMT54448.1 - 0.011 15.7 0.0 0.1 12.5 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain PseudoU_synth_2 PF00849.22 EMT54449.1 - 4.7e-37 127.5 0.1 6.5e-37 127.1 0.1 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EMT54449.1 - 7.3e-11 41.6 0.0 1.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain GSH-S_N PF02951.14 EMT54449.1 - 8.5e-05 22.7 0.0 0.0013 18.8 0.0 2.2 2 0 0 2 2 2 1 Prokaryotic glutathione synthetase, N-terminal domain DUF3892 PF13031.6 EMT54449.1 - 0.018 15.7 0.0 0.034 14.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) S4_2 PF13275.6 EMT54449.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 S4 domain Peptidase_A8 PF01252.18 EMT54450.1 - 6.2e-39 133.4 8.6 7.1e-39 133.3 8.6 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II DUF3488 PF11992.8 EMT54450.1 - 0.01 14.8 0.2 0.013 14.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) ATPase_gene1 PF09527.10 EMT54450.1 - 0.042 14.0 0.2 0.042 14.0 0.2 3.1 2 1 1 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Shigella_OspC PF06128.11 EMT54450.1 - 0.15 11.8 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Shigella flexneri OspC protein RIO1 PF01163.22 EMT54451.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PGM_PMM_I PF02878.16 EMT54452.1 - 3.6e-41 140.1 0.2 9.4e-41 138.8 0.2 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EMT54452.1 - 1.2e-26 93.2 0.0 2.5e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EMT54452.1 - 4.7e-25 88.2 0.0 1.1e-24 87.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EMT54452.1 - 9.6e-12 44.9 0.0 3.1e-11 43.3 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain CpcD PF01383.21 EMT54452.1 - 0.048 13.9 0.2 0.13 12.6 0.1 1.8 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain DUF3638 PF12340.8 EMT54452.1 - 0.13 11.6 0.0 15 4.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3638) NTP_transferase PF00483.23 EMT54453.1 - 4.5e-17 62.4 0.0 8e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase PGM_PMM_I PF02878.16 EMT54453.1 - 1.8e-13 50.3 0.0 3.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Hexapep PF00132.24 EMT54453.1 - 1.2e-09 37.5 9.9 0.00027 20.5 1.4 3.9 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EMT54453.1 - 2.1e-07 31.5 0.0 0.00032 21.1 0.0 2.6 2 0 0 2 2 2 2 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EMT54453.1 - 0.0048 16.6 4.2 0.19 11.5 1.8 3.0 2 1 1 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4912 PF16258.5 EMT54454.1 - 7.3e-17 61.7 0.0 8.9e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4912) 6PF2K PF01591.18 EMT54454.1 - 0.19 11.0 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Mn_catalase PF05067.12 EMT54455.1 - 5.1e-38 130.7 0.3 1.6e-37 129.1 0.3 1.6 1 1 0 1 1 1 1 Manganese containing catalase MSA-2c PF12238.8 EMT54456.1 - 0.32 11.0 1.4 0.35 10.8 1.4 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c MFS_1 PF07690.16 EMT54457.1 - 3.2e-34 118.4 50.6 3.2e-34 118.4 50.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT54457.1 - 2.6e-07 29.9 11.4 2.6e-07 29.9 11.4 3.5 2 2 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.6 EMT54457.1 - 0.00032 19.4 2.8 0.00032 19.4 2.8 2.5 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_4 PF06779.14 EMT54457.1 - 0.43 9.8 30.1 0.8 8.9 29.9 1.4 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Recombinase PF07508.13 EMT54458.1 - 1.8e-24 86.1 2.7 4.5e-24 84.8 0.0 2.9 3 1 0 3 3 3 1 Recombinase Resolvase PF00239.21 EMT54458.1 - 3.4e-09 36.9 5.2 6.7e-09 36.0 0.2 2.8 3 0 0 3 3 3 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 EMT54458.1 - 0.0065 17.0 0.1 0.013 16.0 0.1 1.5 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Atg14 PF10186.9 EMT54458.1 - 0.0096 15.0 6.1 0.015 14.5 6.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 EMT54458.1 - 0.037 14.1 13.3 0.066 13.3 13.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Thioredoxin_11 PF18078.1 EMT54458.1 - 0.062 13.4 1.1 0.13 12.4 1.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain FPP PF05911.11 EMT54458.1 - 0.085 11.0 10.1 0.12 10.6 10.1 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Exonuc_VII_L PF02601.15 EMT54458.1 - 0.32 10.5 6.3 0.57 9.7 6.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Gp-FAR-1 PF05823.12 EMT54458.1 - 0.49 10.8 7.0 0.92 9.8 7.0 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PHM7_cyt PF14703.6 EMT54458.1 - 2.9 8.1 11.1 6.3 7.0 9.6 2.1 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter FapA PF03961.13 EMT54458.1 - 5.4 5.5 8.4 8.7 4.8 8.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A HAUS6_N PF14661.6 EMT54458.1 - 8.7 5.9 12.0 25 4.4 12.0 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Mn_catalase PF05067.12 EMT54459.1 - 1.3e-26 93.3 0.0 1.5e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Manganese containing catalase CotJB PF12652.7 EMT54460.1 - 2.1e-27 95.1 1.9 2.4e-27 94.9 1.9 1.0 1 0 0 1 1 1 1 CotJB protein GspL_C PF12693.7 EMT54460.1 - 0.031 14.1 0.1 0.039 13.8 0.1 1.1 1 0 0 1 1 1 0 GspL periplasmic domain CotJA PF11007.8 EMT54461.1 - 1.3e-11 44.1 1.7 1.3e-11 44.1 1.7 1.6 2 0 0 2 2 2 1 Spore coat associated protein JA (CotJA) DUF4247 PF14042.6 EMT54462.1 - 1.4e-32 113.0 2.5 2.7e-32 112.1 2.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4247) LPAM_1 PF08139.12 EMT54462.1 - 0.078 13.5 0.9 0.14 12.7 0.9 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF4178 PF13785.6 EMT54463.1 - 2.2e-24 86.2 1.0 2.6e-24 86.0 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4178) DUF1344 PF07076.11 EMT54463.1 - 0.0031 17.4 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1344) NlpE PF04170.12 EMT54463.1 - 0.0057 17.6 0.1 0.4 11.7 0.0 2.1 2 0 0 2 2 2 1 NlpE N-terminal domain DUF350 PF03994.14 EMT54464.1 - 5.6e-10 39.2 3.9 1.8e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Domain of Unknown Function (DUF350) DUF3792 PF12670.7 EMT54464.1 - 0.002 18.3 8.3 0.0032 17.6 8.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3792) Ycf70 PF17382.2 EMT54464.1 - 0.3 11.5 1.3 1.1 9.8 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized Ycf70-like Bac_export_2 PF01312.19 EMT54464.1 - 0.65 9.2 5.2 0.51 9.5 0.7 2.0 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family PspA_IM30 PF04012.12 EMT54465.1 - 6.5e-48 163.2 43.6 7.4e-48 163.0 43.6 1.0 1 0 0 1 1 1 1 PspA/IM30 family PRKG1_interact PF15898.5 EMT54465.1 - 0.00075 20.4 14.6 0.00075 20.4 14.6 2.9 1 1 0 2 2 2 1 cGMP-dependent protein kinase interacting domain DUF2431 PF10354.9 EMT54465.1 - 0.2 11.9 1.9 0.27 11.5 0.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2431) DUF4145 PF13643.6 EMT54465.1 - 1.8 8.7 15.8 0.74 10.0 2.1 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4145) DUF3452 PF11934.8 EMT54465.1 - 2.2 7.9 8.3 9.9 5.7 3.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) DUF16 PF01519.16 EMT54465.1 - 2.8 8.5 25.1 2.3 8.8 4.3 3.1 1 1 2 3 3 3 0 Protein of unknown function DUF16 Atg14 PF10186.9 EMT54465.1 - 3.1 6.8 20.4 4.6 6.2 20.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EMT54465.1 - 5.4 5.8 34.7 0.79 8.5 28.1 2.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Sulfatase_C PF14707.6 EMT54465.1 - 7.1 7.4 8.3 1.2 9.8 1.9 2.4 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase V_ATPase_I PF01496.19 EMT54465.1 - 7.8 4.3 22.2 27 2.5 21.2 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Topoisom_bac PF01131.20 EMT54466.1 - 1.4e-124 416.3 2.7 1.4e-124 416.3 2.7 1.4 2 0 0 2 2 2 1 DNA topoisomerase Toprim_Crpt PF13342.6 EMT54466.1 - 8.6e-16 57.7 1.6 8.6e-16 57.7 1.6 2.3 2 0 0 2 2 2 1 C-terminal repeat of topoisomerase Toprim PF01751.22 EMT54466.1 - 7.4e-12 45.4 0.0 1.9e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 EMT54466.1 - 0.024 14.4 1.0 0.051 13.4 1.0 1.6 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger LytR_cpsA_psr PF03816.14 EMT54467.1 - 2.2e-40 138.3 0.1 3.1e-40 137.8 0.1 1.2 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain Ribosomal_L12 PF00542.19 EMT54467.1 - 0.087 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain TetR_N PF00440.23 EMT54468.1 - 3.4e-17 62.0 0.1 8.6e-17 60.7 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 EMT54468.1 - 2.4e-10 40.6 1.7 2.8e-10 40.4 0.4 1.8 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 EMT54468.1 - 0.0059 16.8 0.2 0.014 15.6 0.2 1.7 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_20 PF12840.7 EMT54468.1 - 0.018 15.1 0.0 0.053 13.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.6 EMT54468.1 - 0.034 14.6 0.1 0.099 13.1 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain DUF5367 PF17329.2 EMT54469.1 - 0.0012 19.0 1.7 0.0012 19.0 1.7 1.8 1 1 1 2 2 2 1 Family of unknown function (DUF5367) PrgI PF12666.7 EMT54469.1 - 0.14 12.9 5.9 4.2 8.2 0.0 2.5 2 1 0 2 2 2 0 PrgI family protein DPM3 PF08285.11 EMT54469.1 - 6.4 7.0 6.6 2.1 8.6 0.3 2.2 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pyr_redox_2 PF07992.14 EMT54470.1 - 1.4e-27 96.7 0.0 1.7e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT54470.1 - 1.7e-17 63.7 0.1 2.3e-13 50.1 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMT54470.1 - 2.7e-13 50.3 0.1 3.6e-08 33.9 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMT54470.1 - 2.1e-09 37.3 0.1 6.2e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMT54470.1 - 7.5e-09 35.7 0.1 1.8e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMT54470.1 - 6e-08 32.2 1.8 1.4e-07 30.9 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 EMT54470.1 - 3.5e-07 29.7 0.0 1e-06 28.2 0.0 1.6 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EMT54470.1 - 4.4e-06 26.5 2.2 0.0015 18.1 0.7 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EMT54470.1 - 9.4e-06 25.0 0.8 0.003 16.7 0.4 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EMT54470.1 - 6.3e-05 22.4 1.9 0.001 18.4 0.3 2.6 2 1 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 EMT54470.1 - 8.2e-05 21.5 1.4 0.0031 16.3 0.3 2.5 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EMT54470.1 - 0.00033 20.0 0.0 0.001 18.4 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 EMT54470.1 - 0.0004 19.8 0.2 0.53 9.5 0.0 2.1 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 EMT54470.1 - 0.064 12.5 1.0 1.3 8.2 0.2 2.2 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 EMT54470.1 - 0.12 11.2 0.3 0.82 8.4 0.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FMO-like PF00743.19 EMT54470.1 - 0.19 10.1 0.1 5.8 5.2 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like NUDIX PF00293.28 EMT54471.1 - 9.9e-13 48.3 0.2 1.3e-12 47.9 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain MFS_1 PF07690.16 EMT54472.1 - 3e-60 204.0 50.8 3.2e-50 171.0 34.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT54472.1 - 1.7e-07 30.0 15.2 2.4e-07 29.6 15.2 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.24 EMT54472.1 - 6.2e-06 25.3 12.9 6.2e-06 25.3 12.9 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EMT54472.1 - 7.6e-05 21.3 5.4 7.6e-05 21.3 5.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) INSIG PF07281.12 EMT54472.1 - 0.00045 19.9 0.9 0.07 12.8 0.0 3.7 4 0 0 4 4 4 1 Insulin-induced protein (INSIG) HBS1_N PF08938.10 EMT54472.1 - 0.016 15.5 0.5 0.027 14.8 0.5 1.3 1 0 0 1 1 1 0 HBS1 N-terminus YwcE PF17368.2 EMT54472.1 - 1.5 9.6 6.3 43 4.8 1.1 3.7 3 1 0 3 3 3 0 Spore morphogenesis and germination YwcE DUF3522 PF12036.8 EMT54472.1 - 5.1 7.3 9.6 0.12 12.7 0.3 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3522) MR_MLE_C PF13378.6 EMT54473.1 - 2.1e-46 158.3 0.0 2.9e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EMT54473.1 - 9.8e-07 29.0 0.0 1.6e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain zf-dskA_traR PF01258.17 EMT54474.1 - 1.3e-09 37.9 1.0 2.4e-09 37.0 1.0 1.5 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger Chordopox_RPO7 PF05864.12 EMT54474.1 - 0.15 12.4 0.2 1.4 9.2 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) tRNA-synt_1 PF00133.22 EMT54475.1 - 7e-216 718.1 0.0 8.3e-216 717.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMT54475.1 - 3.1e-30 105.1 0.1 6e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EMT54475.1 - 1.1e-25 90.2 0.1 1.2e-13 50.6 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EMT54475.1 - 5e-10 39.2 0.0 2.7e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 EMT54475.1 - 1.7e-06 27.7 0.0 3.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 EMT54475.1 - 0.00016 21.4 1.1 0.00037 20.3 1.1 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1f PF01921.18 EMT54475.1 - 0.002 17.1 0.0 0.0055 15.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (K) DivIVA PF05103.13 EMT54476.1 - 2.3e-49 166.8 9.4 2.8e-49 166.6 9.4 1.1 1 0 0 1 1 1 1 DivIVA protein Sec34 PF04136.15 EMT54476.1 - 0.0024 17.7 1.9 0.91 9.4 0.0 2.4 1 1 0 2 2 2 2 Sec34-like family V-ATPase_G_2 PF16999.5 EMT54476.1 - 0.0085 16.5 12.2 0.016 15.6 11.3 2.0 1 1 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EMT54476.1 - 0.035 14.2 12.6 0.071 13.2 11.7 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Citrate_synt PF00285.21 EMT54476.1 - 0.041 12.9 0.7 0.048 12.7 0.7 1.1 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain DUF1664 PF07889.12 EMT54476.1 - 0.073 13.1 6.7 0.077 13.0 3.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GCN5L1 PF06320.13 EMT54476.1 - 0.24 11.6 8.6 4.5 7.5 0.1 2.1 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF883 PF05957.13 EMT54476.1 - 0.24 12.0 7.7 0.59 10.8 4.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MDM1 PF15501.6 EMT54476.1 - 0.38 9.9 3.5 0.72 8.9 3.6 1.5 1 1 0 1 1 1 0 Nuclear protein MDM1 vATP-synt_E PF01991.18 EMT54476.1 - 1.4 8.3 18.0 0.098 12.1 10.9 2.0 1 1 0 2 2 2 0 ATP synthase (E/31 kDa) subunit TMPIT PF07851.13 EMT54476.1 - 1.6 7.9 6.5 2 7.6 6.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein YlmH_RBD PF17774.1 EMT54477.1 - 1e-22 80.2 0.0 1.6e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA-binding domain in YlmH S4 PF01479.25 EMT54477.1 - 1.4e-07 31.1 0.1 2.7e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 S4 domain YGGT PF02325.17 EMT54478.1 - 1.3e-21 76.7 2.2 1.8e-21 76.4 2.2 1.2 1 0 0 1 1 1 1 YGGT family SepF PF04472.12 EMT54479.1 - 7.8e-31 106.2 0.1 1e-30 105.8 0.1 1.2 1 0 0 1 1 1 1 Cell division protein SepF Peptidase_C78 PF07910.13 EMT54479.1 - 0.027 13.9 0.0 0.049 13.1 0.0 1.4 2 0 0 2 2 2 0 Peptidase family C78 Ala_racemase_N PF01168.20 EMT54480.1 - 1.6e-18 67.2 0.0 1.8e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Raco_middle PF17651.1 EMT54480.1 - 0.23 11.1 0.3 3.7 7.2 0.1 2.3 1 1 1 2 2 2 0 RACo middle region Cu-oxidase_4 PF02578.15 EMT54481.1 - 3e-77 259.3 0.0 3.5e-77 259.1 0.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase PRC PF05239.16 EMT54482.1 - 1.2e-15 57.4 1.5 1.4e-15 57.1 1.5 1.1 1 0 0 1 1 1 1 PRC-barrel domain Sigma70_r2 PF04542.14 EMT54483.1 - 6.6e-18 64.2 0.0 1.1e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EMT54483.1 - 7.7e-16 57.4 1.8 6.1e-14 51.3 0.7 2.8 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 EMT54483.1 - 9.3e-11 41.7 0.4 1.3e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 EMT54483.1 - 6.2e-07 29.0 1.4 1.4e-06 27.8 0.7 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_31 PF13560.6 EMT54483.1 - 0.0002 21.6 0.3 0.00087 19.6 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain KORA PF16509.5 EMT54483.1 - 0.00022 21.4 0.4 0.00043 20.5 0.4 1.5 1 0 0 1 1 1 1 TrfB plasmid transcriptional repressor HTH_23 PF13384.6 EMT54483.1 - 0.00024 20.8 0.1 0.0036 17.0 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_3 PF01381.22 EMT54483.1 - 0.00025 21.1 0.1 0.001 19.1 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_28 PF13518.6 EMT54483.1 - 0.0005 20.2 0.1 0.0081 16.3 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain Trp_repressor PF01371.19 EMT54483.1 - 0.006 16.7 0.4 0.038 14.1 0.2 2.3 2 0 0 2 2 2 1 Trp repressor protein Sigma70_ECF PF07638.11 EMT54483.1 - 0.017 15.0 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 ECF sigma factor GerE PF00196.19 EMT54483.1 - 0.022 14.3 0.2 0.022 14.3 0.2 2.3 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family HTH_37 PF13744.6 EMT54483.1 - 0.031 14.2 0.1 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 EMT54483.1 - 0.052 13.4 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_26 PF13443.6 EMT54483.1 - 0.16 12.4 0.0 0.61 10.6 0.0 1.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Sigma70_r2 PF04542.14 EMT54484.1 - 5.7e-20 70.9 0.2 1.2e-19 69.8 0.0 1.7 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EMT54484.1 - 2.4e-16 59.0 1.6 5.3e-16 57.9 1.6 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_3 PF01381.22 EMT54484.1 - 5.4e-06 26.4 0.1 1.4e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EMT54484.1 - 0.00011 22.5 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EMT54484.1 - 0.00042 19.9 0.4 0.0018 17.9 0.4 2.1 1 1 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 EMT54484.1 - 0.00092 18.9 0.1 0.0026 17.5 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_37 PF13744.6 EMT54484.1 - 0.0061 16.5 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EMT54484.1 - 0.0062 16.4 0.0 0.022 14.6 0.0 2.0 1 0 0 1 1 1 1 MarR family KORA PF16509.5 EMT54484.1 - 0.0087 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 TrfB plasmid transcriptional repressor HTH_19 PF12844.7 EMT54484.1 - 0.013 15.5 0.6 0.013 15.5 0.6 2.8 3 1 0 3 3 3 0 Helix-turn-helix domain Trp_repressor PF01371.19 EMT54484.1 - 0.026 14.6 0.5 0.053 13.6 0.2 1.7 2 0 0 2 2 2 0 Trp repressor protein Phage_CII PF05269.11 EMT54484.1 - 0.033 14.4 0.2 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage CII protein HTH_17 PF12728.7 EMT54484.1 - 0.042 14.1 0.1 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_25 PF13413.6 EMT54484.1 - 0.045 13.6 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF722 PF05263.11 EMT54484.1 - 0.06 13.6 0.7 0.1 12.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Phage_CI_repr PF07022.13 EMT54484.1 - 0.083 13.0 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain TBPIP PF07106.13 EMT54484.1 - 0.18 11.8 1.1 0.45 10.5 0.1 2.1 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain HTH_Tnp_4 PF13613.6 EMT54484.1 - 0.33 10.7 2.5 2.9 7.7 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix of DDE superfamily endonuclease Peptidase_U4 PF03419.13 EMT54485.1 - 2.7e-85 286.1 0.4 3.1e-85 285.9 0.4 1.0 1 0 0 1 1 1 1 Sporulation factor SpoIIGA Tubulin PF00091.25 EMT54486.1 - 5.1e-41 141.0 0.4 1.1e-40 140.0 0.4 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 EMT54486.1 - 2e-34 117.8 1.9 2e-34 117.8 1.9 2.4 2 0 0 2 2 2 1 FtsZ family, C-terminal domain NAD_binding_10 PF13460.6 EMT54486.1 - 0.029 14.3 0.6 0.13 12.2 0.1 2.3 2 1 0 2 2 2 0 NAD(P)H-binding FtsA PF14450.6 EMT54487.1 - 3.7e-34 117.2 5.3 7.2e-23 81.0 0.2 2.1 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 EMT54487.1 - 1.1e-29 102.6 2.8 2.8e-29 101.3 2.8 1.7 1 0 0 1 1 1 1 SHS2 domain inserted in FTSA MreB_Mbl PF06723.13 EMT54487.1 - 3.1e-10 39.4 6.3 1.8e-09 36.9 1.2 2.4 2 0 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.8 EMT54487.1 - 4.9e-07 29.1 1.2 0.0057 15.7 0.0 3.2 3 0 0 3 3 3 3 Type IV pilus assembly protein PilM; EutA PF06277.11 EMT54487.1 - 1.2e-05 24.4 0.3 1.2e-05 24.4 0.3 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutA Peptidase_C25_C PF03785.14 EMT54487.1 - 0.13 12.1 0.5 0.47 10.3 0.5 1.9 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain DUF1290 PF06947.12 EMT54488.1 - 1.3e-34 118.1 5.9 1.8e-34 117.7 5.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1290) RseC_MucC PF04246.12 EMT54488.1 - 6 6.8 6.8 1.6 8.7 0.5 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF881 PF05949.12 EMT54489.1 - 4e-32 111.1 0.8 4.8e-32 110.8 0.2 1.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF881) DUF4094 PF13334.6 EMT54489.1 - 0.0087 16.5 0.3 0.015 15.7 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) DUF881 PF05949.12 EMT54490.1 - 1.5e-46 157.9 0.9 2.2e-46 157.4 0.9 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF881) HisG_C PF08029.11 EMT54490.1 - 0.027 14.6 0.2 0.06 13.5 0.1 1.7 1 1 0 1 1 1 0 HisG, C-terminal domain Ysc84 PF04366.12 EMT54490.1 - 0.051 13.3 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Las17-binding protein actin regulator POTRA_1 PF08478.10 EMT54491.1 - 8.2e-12 45.3 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 POTRA domain, FtsQ-type FtsQ PF03799.15 EMT54491.1 - 2.2e-05 25.3 0.0 3.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Cell division protein FtsQ SNARE PF05739.19 EMT54491.1 - 0.083 12.9 0.5 0.17 11.9 0.5 1.5 1 0 0 1 1 1 0 SNARE domain EPSP_synthase PF00275.20 EMT54492.1 - 7e-87 291.8 0.3 8e-87 291.6 0.3 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) MurB_C PF02873.16 EMT54493.1 - 1.2e-31 109.2 0.0 2.3e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 EMT54493.1 - 6.7e-21 74.5 0.3 1.2e-20 73.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_transf_28 PF03033.20 EMT54494.1 - 1.1e-47 161.6 0.3 2.3e-47 160.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 EMT54494.1 - 6.7e-40 136.8 0.0 9.6e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_4 PF13579.6 EMT54494.1 - 3.6e-05 24.3 0.2 0.00013 22.4 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EMT54494.1 - 5.9e-05 23.1 0.0 0.00033 20.7 0.0 2.1 2 1 1 3 3 3 1 Glycosyltransferase Family 4 Epimerase_2 PF02350.19 EMT54494.1 - 0.0089 14.9 0.0 0.083 11.7 0.0 2.3 2 1 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase UDPGT PF00201.18 EMT54494.1 - 0.018 13.9 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Alg14 PF08660.11 EMT54494.1 - 0.12 12.3 0.0 0.51 10.2 0.0 2.1 1 1 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like FTSW_RODA_SPOVE PF01098.19 EMT54495.1 - 1e-118 396.4 32.3 1.2e-118 396.2 32.3 1.0 1 0 0 1 1 1 1 Cell cycle protein Mur_ligase_M PF08245.12 EMT54496.1 - 2.2e-26 93.1 0.0 4e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EMT54496.1 - 4.8e-13 49.2 1.1 5.1e-11 42.7 0.0 3.7 4 0 0 4 4 4 1 Mur ligase family, glutamate ligase domain 2-Hacid_dh_C PF02826.19 EMT54496.1 - 0.00026 20.4 0.4 0.00055 19.3 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EMT54496.1 - 0.017 15.3 0.7 0.094 13.0 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain ThiW PF09512.10 EMT54496.1 - 0.039 14.1 1.3 1.3 9.1 0.5 2.3 2 0 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) Pyr_redox PF00070.27 EMT54496.1 - 0.043 14.4 0.3 0.13 12.8 0.3 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 EMT54496.1 - 0.064 13.8 0.0 0.18 12.3 0.0 1.9 1 1 0 1 1 1 0 XdhC Rossmann domain Pyr_redox_3 PF13738.6 EMT54496.1 - 0.12 11.6 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mur_ligase PF01225.25 EMT54496.1 - 0.13 12.6 0.5 0.49 10.7 0.2 2.2 2 0 0 2 2 2 0 Mur ligase family, catalytic domain Glycos_transf_4 PF00953.21 EMT54497.1 - 1.7e-39 135.4 15.3 1.7e-39 135.4 15.3 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 EMT54497.1 - 0.00016 21.0 3.4 0.00016 21.0 3.4 2.3 2 0 0 2 2 2 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 DUF4834 PF16118.5 EMT54497.1 - 2.5 9.1 0.0 2.5 9.1 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) Mur_ligase_M PF08245.12 EMT54498.1 - 2.2e-58 197.5 2.6 3.1e-58 197.0 2.6 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EMT54498.1 - 2.3e-23 82.2 0.0 2.7e-22 78.8 0.0 2.6 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 EMT54498.1 - 2.1e-14 53.6 0.0 5.3e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Transpeptidase PF00905.22 EMT54499.1 - 7e-83 278.3 0.0 1.5e-82 277.3 0.0 1.5 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 EMT54499.1 - 6.8e-23 81.9 0.3 1.9e-21 77.2 0.3 2.4 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain PASTA PF03793.19 EMT54499.1 - 1.4e-07 31.2 0.1 3.6e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 PASTA domain Transpeptidase PF00905.22 EMT54500.1 - 9e-84 281.3 1.0 2.5e-83 279.8 0.7 1.9 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 EMT54500.1 - 1.4e-19 71.1 0.8 6.7e-18 65.7 0.8 2.8 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain PASTA PF03793.19 EMT54500.1 - 1.5e-15 56.8 12.7 6.5e-08 32.3 0.6 4.7 5 0 0 5 5 5 2 PASTA domain IIGP PF05049.13 EMT54500.1 - 0.012 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 EMT54500.1 - 0.023 14.5 0.1 0.064 13.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DivIC PF04977.15 EMT54501.1 - 1.6e-05 24.6 0.3 2.6e-05 23.9 0.3 1.3 1 0 0 1 1 1 1 Septum formation initiator FtsL PF04999.13 EMT54501.1 - 0.0077 16.2 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 Cell division protein FtsL YabA PF06156.13 EMT54501.1 - 0.025 15.2 1.0 0.04 14.5 1.0 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF5305 PF17231.2 EMT54501.1 - 0.034 13.6 0.5 0.059 12.8 0.3 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5305) CCDC106 PF15794.5 EMT54501.1 - 1.3 8.7 8.6 0.18 11.5 4.6 1.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 106 Methyltransf_5 PF01795.19 EMT54502.1 - 5e-130 433.5 0.0 5.7e-130 433.3 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 EMT54502.1 - 0.017 14.9 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain rRNA_methylase PF06962.12 EMT54502.1 - 0.027 14.4 0.0 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Putative rRNA methylase Methyltransf_25 PF13649.6 EMT54502.1 - 0.057 14.1 0.0 0.18 12.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MraZ PF02381.18 EMT54503.1 - 1.1e-51 172.7 0.0 4.1e-25 87.6 0.0 2.0 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like DUF2375 PF09558.10 EMT54503.1 - 0.18 11.8 0.0 0.93 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2375) AdoHcyase_NAD PF00670.21 EMT54504.1 - 1e-54 185.0 1.4 1e-54 185.0 1.4 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 EMT54504.1 - 4.3e-54 183.7 0.0 6.3e-28 97.8 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.19 EMT54504.1 - 7.4e-13 48.2 0.1 1.5e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EMT54504.1 - 4.6e-10 39.3 0.6 9.9e-10 38.2 0.6 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox_2 PF07992.14 EMT54504.1 - 0.027 13.7 0.4 0.046 13.0 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMT54504.1 - 0.069 12.4 2.5 0.22 10.8 2.5 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LysR_substrate PF03466.20 EMT54505.1 - 3.8e-54 183.2 0.0 4.8e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT54505.1 - 1.8e-20 72.6 0.3 3.1e-20 71.9 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family AA_permease_2 PF13520.6 EMT54506.1 - 1.2e-43 149.6 48.3 1.4e-43 149.3 48.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMT54506.1 - 3.4e-30 105.1 44.1 4.7e-30 104.6 44.1 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 EMT54506.1 - 9.5e-10 37.8 14.9 9.5e-10 37.8 14.9 2.2 1 1 1 2 2 2 1 Spore germination protein Trp_Tyr_perm PF03222.13 EMT54506.1 - 0.22 10.5 34.5 0.33 9.9 6.5 2.6 1 1 2 3 3 3 0 Tryptophan/tyrosine permease family TssN PF17555.2 EMT54506.1 - 1.2 8.5 10.5 0.076 12.4 4.0 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN SLH PF00395.20 EMT54508.1 - 3.9e-23 81.2 0.9 6.4e-10 38.9 0.0 3.5 3 0 0 3 3 3 3 S-layer homology domain Mago-bind PF09282.10 EMT54508.1 - 0.09 12.7 0.1 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Mago binding BshC PF10079.9 EMT54509.1 - 1.3e-147 492.8 0.0 1.5e-147 492.7 0.0 1.0 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC Cupin_2 PF07883.11 EMT54510.1 - 3.4e-15 55.5 0.3 5.3e-15 54.9 0.3 1.3 1 0 0 1 1 1 1 Cupin domain HTH_3 PF01381.22 EMT54510.1 - 1e-10 41.5 0.1 1.5e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EMT54510.1 - 3.4e-06 27.3 0.0 5.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EMT54510.1 - 1.3e-05 25.1 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MannoseP_isomer PF01050.18 EMT54510.1 - 2.1e-05 24.4 0.0 2.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 EMT54510.1 - 0.00016 21.6 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_26 PF13443.6 EMT54510.1 - 0.00052 20.4 0.0 0.00078 19.8 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Cupin_3 PF05899.12 EMT54510.1 - 0.0032 17.1 0.8 0.0078 15.9 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF861) HTH_25 PF13413.6 EMT54510.1 - 0.0035 17.2 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Asp_Arg_Hydrox PF05118.15 EMT54510.1 - 0.004 17.0 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase CENP-C_C PF11699.8 EMT54510.1 - 0.006 16.8 0.0 0.016 15.4 0.0 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_1 PF00190.22 EMT54510.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Cupin E1_FCCH PF16190.5 EMT54510.1 - 0.058 13.6 0.1 0.22 11.7 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain KduI PF04962.12 EMT54510.1 - 0.073 12.4 0.1 0.092 12.0 0.1 1.2 1 0 0 1 1 1 0 KduI/IolB family Pirin_C_2 PF17954.1 EMT54510.1 - 0.093 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain DUF3397 PF11877.8 EMT54511.1 - 2.2e-20 72.9 14.6 3.1e-20 72.4 14.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3397) ApbA_C PF08546.11 EMT54512.1 - 1.9e-36 125.0 0.1 1.7e-35 122.0 0.1 2.2 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EMT54512.1 - 9.5e-27 93.5 0.0 1.5e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EMT54512.1 - 2.2e-05 24.9 0.0 8.5e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 EMT54512.1 - 0.0011 19.2 0.0 0.003 17.8 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain DAO PF01266.24 EMT54512.1 - 0.0012 18.5 0.1 0.0018 17.9 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMT54512.1 - 0.0017 18.9 0.0 0.0049 17.4 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EMT54512.1 - 0.0017 18.8 0.0 0.0038 17.6 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EMT54512.1 - 0.0018 17.6 0.4 0.005 16.1 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.23 EMT54512.1 - 0.0044 17.0 0.0 0.0089 16.0 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 EMT54512.1 - 0.014 14.7 0.1 0.025 13.8 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EMT54512.1 - 0.051 13.5 0.1 0.22 11.4 0.0 2.1 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMT54512.1 - 0.06 13.4 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EMT54512.1 - 0.089 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Sacchrp_dh_NADP PF03435.18 EMT54512.1 - 0.11 12.8 0.1 0.22 11.8 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Carboxyl_trans PF01039.22 EMT54513.1 - 2.2e-159 531.2 0.2 2.6e-159 531.0 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EMT54513.1 - 9e-08 31.9 1.7 0.00012 21.6 0.4 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 EMT54513.1 - 0.087 12.1 0.2 0.32 10.3 0.1 1.9 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EMT54514.1 - 2e-69 233.7 0.1 2.2e-69 233.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMT54514.1 - 5.5e-38 131.3 0.3 1.1e-35 123.7 0.4 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 EMT54514.1 - 0.025 13.6 0.0 0.053 12.5 0.0 1.5 1 1 0 1 1 1 0 Serine dehydrogenase proteinase Peptidase_S49 PF01343.18 EMT54514.1 - 0.03 14.3 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 HMGL-like PF00682.19 EMT54515.1 - 1.2e-50 172.5 0.0 1.4e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 HMGL-like ALAD PF00490.21 EMT54515.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase Biotin_lipoyl PF00364.22 EMT54516.1 - 1.1e-19 70.0 6.8 1.2e-19 69.9 6.8 1.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EMT54516.1 - 5.2e-13 48.6 9.3 6.5e-07 29.1 1.6 2.0 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 EMT54516.1 - 1.2e-07 31.2 1.4 0.00083 18.6 0.1 2.0 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 EMT54516.1 - 1.6e-05 24.8 1.4 1.7e-05 24.7 1.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 EMT54516.1 - 1.9e-05 25.3 3.9 0.0061 17.2 0.3 2.0 1 1 1 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.6 EMT54516.1 - 0.00011 22.1 3.1 0.00026 20.9 3.1 1.7 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 EMT54516.1 - 0.0012 18.6 0.8 0.039 13.7 0.1 2.0 1 1 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 NQRA PF05896.11 EMT54516.1 - 0.0016 17.9 1.0 0.0019 17.7 1.0 1.2 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) QRPTase_N PF02749.16 EMT54516.1 - 0.014 15.4 0.9 3.4 7.8 0.1 2.1 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain PASTA PF03793.19 EMT54516.1 - 0.016 15.0 3.4 0.29 11.0 0.3 2.1 1 1 1 2 2 2 0 PASTA domain Peptidase_M23 PF01551.22 EMT54516.1 - 0.022 15.0 6.3 2.4 8.4 1.2 3.1 1 1 1 2 2 2 0 Peptidase family M23 DUF2118 PF09891.9 EMT54516.1 - 0.05 13.6 0.5 0.083 12.8 0.5 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF2254 PF10011.9 EMT54516.1 - 0.07 11.9 0.4 5.4 5.7 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) PYNP_C PF07831.13 EMT54516.1 - 0.075 12.7 2.6 2.1 8.1 0.7 2.1 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain YqfD PF06898.11 EMT54516.1 - 0.76 8.6 6.7 4.1 6.1 2.9 2.0 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD CPSase_L_D2 PF02786.17 EMT54517.1 - 1.7e-78 262.9 0.0 2.7e-78 262.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EMT54517.1 - 1.2e-44 151.4 0.0 3.9e-44 149.7 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EMT54517.1 - 9.1e-39 131.9 0.0 1.6e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EMT54517.1 - 1.8e-12 47.2 0.0 4.7e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EMT54517.1 - 2e-11 43.8 0.0 1.1e-10 41.4 0.0 2.1 3 0 0 3 3 3 1 ATP-grasp domain RimK PF08443.11 EMT54517.1 - 2.1e-06 27.5 0.0 6e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EMT54517.1 - 2.5e-06 27.6 0.0 4.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 EMT54517.1 - 6.5e-05 22.5 0.0 0.00017 21.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EMT54517.1 - 0.0023 17.2 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp LAL_C2 PF18603.1 EMT54517.1 - 0.14 12.3 0.0 0.14 12.3 0.0 2.5 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 Acetyltransf_1 PF00583.25 EMT54518.1 - 5.4e-08 33.1 0.0 7.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT54518.1 - 1.4e-07 31.8 0.0 2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT54518.1 - 3.9e-05 23.6 0.0 7.9e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT54518.1 - 0.082 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Myb_DNA-bind_6 PF13921.6 EMT54519.1 - 0.0004 20.6 0.0 0.0015 18.7 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMT54519.1 - 0.0041 17.3 0.4 0.016 15.4 0.0 2.2 2 1 0 2 2 2 1 Myb-like DNA-binding domain TPR_MLP1_2 PF07926.12 EMT54519.1 - 0.034 14.2 8.1 0.045 13.8 6.5 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4239 PF14023.6 EMT54519.1 - 0.051 13.3 2.4 0.072 12.8 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF4279 PF14106.6 EMT54519.1 - 0.073 13.3 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4279) DASH_Dad4 PF08650.10 EMT54519.1 - 0.14 12.1 4.4 1.6 8.7 0.1 2.5 1 1 1 2 2 2 0 DASH complex subunit Dad4 DUF573 PF04504.14 EMT54519.1 - 0.25 12.0 3.0 26 5.6 0.3 3.0 1 1 1 3 3 3 0 Protein of unknown function, DUF573 YabA PF06156.13 EMT54519.1 - 0.52 11.0 10.1 0.22 12.2 5.5 2.1 2 0 0 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 EMT54519.1 - 0.56 10.3 7.9 0.78 9.8 7.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-Q PF13094.6 EMT54519.1 - 0.71 10.0 11.6 0.13 12.5 6.5 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2570 PF10828.8 EMT54519.1 - 2 8.3 11.0 0.92 9.4 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF745 PF05335.13 EMT54519.1 - 3.4 7.3 10.1 35 4.1 10.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ECH_1 PF00378.20 EMT54520.1 - 1.4e-45 155.6 0.1 1.6e-45 155.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMT54520.1 - 1.2e-31 110.5 0.0 1.4e-31 110.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 EMT54520.1 - 0.0092 15.0 0.1 0.43 9.5 0.1 2.1 1 1 0 1 1 1 1 Serine dehydrogenase proteinase ABATE PF07336.11 EMT54520.1 - 0.053 14.2 1.7 0.058 14.1 0.7 1.6 2 0 0 2 2 2 0 Putative stress-induced transcription regulator CLP_protease PF00574.23 EMT54520.1 - 0.13 12.1 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 Clp protease ArsC PF03960.15 EMT54521.1 - 1.7e-17 63.2 0.0 2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 EMT54521.1 - 2.4e-08 34.0 0.1 1.4e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 EMT54521.1 - 0.015 15.7 0.0 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 EMT54521.1 - 0.072 13.5 0.0 0.2 12.1 0.0 2.0 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N PF02798.20 EMT54521.1 - 0.084 13.2 0.0 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain HTH_20 PF12840.7 EMT54522.1 - 3.1e-09 36.7 0.0 7.6e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain ATC_hydrolase PF14196.6 EMT54522.1 - 0.0013 19.5 0.1 0.0024 18.7 0.1 1.4 1 1 0 1 1 1 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase Rrf2 PF02082.20 EMT54522.1 - 0.0037 17.6 0.0 0.0074 16.6 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator FaeA PF04703.12 EMT54522.1 - 0.017 15.5 0.0 0.069 13.5 0.0 1.9 1 1 1 2 2 2 0 FaeA-like protein XylR_N PF06505.11 EMT54522.1 - 0.054 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Activator of aromatic catabolism HTH_5 PF01022.20 EMT54522.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family V4R PF02830.18 EMT54522.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 V4R domain HTH_11 PF08279.12 EMT54522.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 HTH domain DUF2626 PF11117.8 EMT54523.1 - 6.8e-30 103.6 20.8 8e-30 103.4 20.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2626) NiFe_hyd_3_EhaA PF17367.2 EMT54523.1 - 0.14 12.3 5.0 0.19 11.9 5.0 1.3 1 0 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A ThrE PF06738.12 EMT54523.1 - 2 7.7 8.0 2.1 7.7 8.0 1.0 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF4131 PF13567.6 EMT54523.1 - 7.8 6.1 6.6 11 5.6 6.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Methyltransf_28 PF02636.17 EMT54524.1 - 1.1e-45 156.3 0.0 1.5e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PALP PF00291.25 EMT54524.1 - 0.028 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_12 PF08242.12 EMT54524.1 - 0.15 12.8 0.0 0.31 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RasGEF PF00617.19 EMT54525.1 - 0.078 13.2 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 RasGEF domain DUF4172 PF13776.6 EMT54525.1 - 0.85 10.0 3.5 0.61 10.5 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4172) PGA_cap PF09587.10 EMT54526.1 - 7.8e-74 248.4 0.0 1.1e-73 247.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap PT PF04886.12 EMT54526.1 - 0.00055 19.4 11.2 0.0024 17.4 10.8 2.0 1 1 1 2 2 2 1 PT repeat Lactamase_B PF00753.27 EMT54527.1 - 2.4e-30 106.0 0.2 2.9e-30 105.7 0.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMT54527.1 - 1.1e-10 41.4 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMT54527.1 - 0.00068 19.6 0.0 0.01 15.8 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EMT54527.1 - 0.0041 16.6 0.0 0.037 13.5 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain PDEase_II PF02112.15 EMT54527.1 - 0.075 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II COX7C PF02935.16 EMT54530.1 - 0.15 12.3 0.6 1.7 9.0 1.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc TrbC PF04956.13 EMT54530.1 - 5.2 7.3 7.3 3.1 8.1 3.0 2.3 2 1 0 2 2 2 0 TrbC/VIRB2 family DinB_2 PF12867.7 EMT54531.1 - 1.5e-15 57.8 0.1 2.2e-15 57.3 0.0 1.3 1 1 1 2 2 2 1 DinB superfamily PhoH PF02562.16 EMT54532.1 - 9.1e-55 185.3 0.0 1.2e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein PIN_4 PF13638.6 EMT54532.1 - 2.9e-34 118.2 0.1 4.6e-34 117.5 0.1 1.3 1 0 0 1 1 1 1 PIN domain AAA_30 PF13604.6 EMT54532.1 - 5.2e-10 39.4 0.1 4.7e-09 36.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMT54532.1 - 9.5e-06 26.0 0.0 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMT54532.1 - 0.00021 21.6 0.8 0.0031 17.8 0.8 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMT54532.1 - 0.0035 17.1 0.1 0.44 10.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EMT54532.1 - 0.0071 15.6 0.7 0.091 12.0 0.6 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EMT54532.1 - 0.0074 16.1 0.4 0.013 15.3 0.0 1.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 EMT54532.1 - 0.015 15.1 0.1 0.63 9.8 0.1 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF4411 PF14367.6 EMT54532.1 - 0.044 13.7 0.0 0.75 9.7 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) UvrD-helicase PF00580.21 EMT54532.1 - 0.25 10.8 1.1 0.58 9.6 0.0 1.9 2 1 0 3 3 3 0 UvrD/REP helicase N-terminal domain Spore_YhcN_YlaJ PF09580.10 EMT54533.1 - 1.2e-18 67.7 0.1 2e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Cys_Met_Meta_PP PF01053.20 EMT54534.1 - 7.3e-146 485.6 0.0 8.2e-146 485.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EMT54534.1 - 6.7e-08 32.1 0.1 1.1e-07 31.4 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMT54534.1 - 2.3e-07 30.5 2.1 3.8e-07 29.7 2.1 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EMT54534.1 - 0.00014 20.6 0.1 0.00019 20.1 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 EMT54534.1 - 0.00029 19.9 0.0 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 EMT54534.1 - 0.00048 19.1 0.0 0.00073 18.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Pox_T4_C PF04490.12 EMT54534.1 - 0.085 13.0 0.1 0.59 10.3 0.1 2.0 1 1 1 2 2 2 0 Poxvirus T4 protein, C terminus DUF2498 PF10692.9 EMT54534.1 - 0.1 12.5 0.0 21 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2498) Cys_Met_Meta_PP PF01053.20 EMT54535.1 - 2.3e-144 480.7 0.0 2.6e-144 480.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMT54535.1 - 3.9e-05 22.8 0.0 0.00013 21.0 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMT54535.1 - 8.9e-05 21.9 0.1 0.0069 15.7 0.0 2.6 1 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EMT54535.1 - 0.00017 20.9 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.13 EMT54535.1 - 0.092 11.7 0.0 0.15 11.0 0.0 1.5 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase Putative_PNPOx PF01243.20 EMT54536.1 - 4.7e-07 29.9 0.0 6.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PA-IIL PF07472.11 EMT54538.1 - 0.0047 17.2 7.1 1.9 8.8 0.1 4.1 3 1 1 4 4 4 2 Fucose-binding lectin II (PA-IIL) Big_6 PF17936.1 EMT54538.1 - 0.0056 16.9 5.4 0.81 10.0 0.0 3.8 3 1 0 3 3 3 1 Bacterial Ig domain CBM60 PF16841.5 EMT54538.1 - 0.089 13.2 5.3 4.2 7.9 0.0 3.7 3 1 0 3 3 3 0 Ca-dependent carbohydrate-binding module xylan-binding DBB PF14545.6 EMT54538.1 - 0.45 10.4 2.4 20 5.1 0.3 3.4 3 1 0 3 3 3 0 Dof, BCAP, and BANK (DBB) motif, YlaH PF14036.6 EMT54540.1 - 1.2e-18 67.2 13.0 1.4e-18 66.9 13.0 1.1 1 0 0 1 1 1 1 YlaH-like protein XPC-binding PF09280.11 EMT54541.1 - 0.0099 15.6 0.4 0.016 14.9 0.0 1.5 2 0 0 2 2 2 1 XPC-binding domain GSHPx PF00255.19 EMT54542.1 - 8.5e-43 144.4 0.0 1.1e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EMT54542.1 - 6.8e-05 22.8 0.0 0.00013 21.8 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family GTP_EFTU PF00009.27 EMT54543.1 - 6.8e-58 195.4 0.1 1.1e-57 194.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EMT54543.1 - 1.6e-23 82.5 0.1 4e-23 81.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMT54543.1 - 3.8e-15 56.0 3.0 2.2e-14 53.6 1.9 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EMT54543.1 - 3.7e-07 30.1 0.1 9.3e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EMT54543.1 - 4.4e-06 26.8 0.1 1e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMT54543.1 - 0.003 17.1 0.6 0.034 13.7 0.2 2.9 3 1 0 3 3 3 1 Ferrous iron transport protein B Arf PF00025.21 EMT54543.1 - 0.0055 16.2 0.1 0.02 14.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Septin PF00735.18 EMT54543.1 - 0.0071 15.7 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Septin Ras PF00071.22 EMT54543.1 - 0.042 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Ras family Spore_YhcN_YlaJ PF09580.10 EMT54544.1 - 1.5e-15 57.6 11.8 2.1e-15 57.2 11.8 1.2 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) AdoMet_dc PF02675.15 EMT54545.1 - 2.6e-36 124.1 0.0 3.1e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase DUF2075 PF09848.9 EMT54546.1 - 0.082 12.1 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF4446 PF14584.6 EMT54547.1 - 1.3e-47 161.5 0.0 1.5e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) DUF2118 PF09891.9 EMT54548.1 - 0.035 14.1 0.1 0.045 13.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF1054 PF06335.12 EMT54549.1 - 1.2e-80 270.1 0.0 1.4e-80 269.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1054) NMO PF03060.15 EMT54550.1 - 1.3e-69 235.1 0.7 7.9e-68 229.3 0.7 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EMT54550.1 - 4.7e-09 35.7 1.0 3e-08 33.1 1.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EMT54550.1 - 7.1e-08 31.9 7.1 3.3e-07 29.7 6.5 1.9 1 1 1 2 2 2 1 FMN-dependent dehydrogenase ThiG PF05690.14 EMT54550.1 - 5.8e-06 25.8 0.6 8.9e-06 25.2 0.6 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 EMT54550.1 - 0.00087 18.5 0.7 0.0015 17.8 0.0 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EMT54550.1 - 0.018 14.5 0.2 0.031 13.7 0.2 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein SOR_SNZ PF01680.17 EMT54550.1 - 0.071 12.9 0.3 0.16 11.8 0.3 1.5 1 0 0 1 1 1 0 SOR/SNZ family DUF561 PF04481.12 EMT54550.1 - 0.11 11.6 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) OKR_DC_1 PF01276.20 EMT54551.1 - 3.5e-108 362.0 0.5 2.6e-107 359.2 0.5 1.9 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 EMT54551.1 - 2.8e-12 47.1 0.1 7e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain Aminotran_5 PF00266.19 EMT54551.1 - 3.1e-10 39.6 1.9 4.9e-10 38.9 1.9 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMT54551.1 - 1.1e-09 37.9 0.7 5.7e-09 35.6 0.7 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMT54551.1 - 4.3e-09 36.2 3.4 7.4e-09 35.4 3.4 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 EMT54551.1 - 3.2e-08 32.7 0.0 4.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 EMT54551.1 - 2.4e-07 30.3 1.9 4.9e-07 29.3 1.9 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DUF4904 PF16247.5 EMT54551.1 - 0.11 12.3 0.0 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4904) Herpes_UL69 PF05459.12 EMT54551.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family DHO_dh PF01180.21 EMT54552.1 - 1.1e-19 70.8 0.0 2.3e-19 69.7 0.0 1.6 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase IMPDH PF00478.25 EMT54552.1 - 0.0071 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PD40 PF07676.12 EMT54553.1 - 0.65 10.0 5.8 5.8 7.0 0.4 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SR1P PF13790.6 EMT54554.1 - 9.7e-19 67.2 4.0 1.1e-18 67.1 4.0 1.0 1 0 0 1 1 1 1 SR1 protein Hydrolase_4 PF12146.8 EMT54555.1 - 2.2e-65 220.3 0.0 2.5e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMT54555.1 - 2.2e-16 61.1 4.8 2.6e-16 60.9 4.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMT54555.1 - 6.3e-16 58.8 0.0 1.3e-11 44.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EMT54555.1 - 3.8e-07 30.2 0.0 1.5e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EMT54555.1 - 0.0022 18.1 0.1 0.004 17.3 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 EMT54555.1 - 0.0024 17.7 0.5 0.089 12.6 0.0 2.9 2 2 1 3 3 3 1 Serine hydrolase BCA_ABC_TP_C PF12399.8 EMT54555.1 - 0.0034 17.3 0.2 0.0059 16.5 0.2 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter Abhydrolase_2 PF02230.16 EMT54555.1 - 0.0042 16.9 0.2 0.14 12.0 0.2 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase PGAP1 PF07819.13 EMT54555.1 - 0.0064 16.2 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 EMT54555.1 - 0.0098 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase LCAT PF02450.15 EMT54555.1 - 0.013 14.7 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Palm_thioest PF02089.15 EMT54555.1 - 0.018 14.9 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PhoPQ_related PF10142.9 EMT54555.1 - 0.025 13.2 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein DUF3089 PF11288.8 EMT54555.1 - 0.047 13.2 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_5 PF12695.7 EMT54555.1 - 0.049 13.4 0.0 0.55 10.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF915 PF06028.11 EMT54555.1 - 0.072 12.4 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 EMT54555.1 - 0.096 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 EMT54555.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PAF-AH_p_II PF03403.13 EMT54555.1 - 0.17 10.3 0.1 0.37 9.2 0.0 1.5 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF3055 PF11256.8 EMT54556.1 - 1e-30 105.8 0.1 1.2e-30 105.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3055) MarR PF01047.22 EMT54557.1 - 4.7e-08 32.8 0.0 1.4e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EMT54557.1 - 6.1e-06 26.0 0.0 1.7e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 EMT54557.1 - 5e-05 23.7 0.1 0.00034 21.0 0.0 2.3 3 0 0 3 3 3 1 Winged helix DNA-binding domain HTH_34 PF13601.6 EMT54557.1 - 0.0041 17.3 0.0 0.0065 16.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 EMT54557.1 - 0.013 15.4 0.1 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB E2F_TDP PF02319.20 EMT54557.1 - 0.018 15.1 0.1 0.052 13.6 0.1 1.9 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain DUF1885 PF08968.10 EMT54558.1 - 1.6e-55 186.7 0.0 1.9e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1885) Glucosaminidase PF01832.20 EMT54559.1 - 8.8e-21 74.2 0.1 1.2e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Ub-RnfH PF03658.14 EMT54559.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RnfH family Ubiquitin DUF4912 PF16258.5 EMT54560.1 - 3.5e-12 46.6 0.0 4.6e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4912) MG2 PF01835.19 EMT54561.1 - 0.0079 16.6 0.1 0.014 15.9 0.1 1.4 1 0 0 1 1 1 1 MG2 domain Peptidase_M20 PF01546.28 EMT54562.1 - 3.7e-27 95.4 0.8 5e-27 95.0 0.8 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT54562.1 - 4.5e-10 39.4 0.1 1.1e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Aminotran_3 PF00202.21 EMT54563.1 - 1.5e-100 336.8 0.0 1.8e-100 336.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMT54563.1 - 0.0019 17.4 0.0 0.0029 16.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DUF438 PF04282.13 EMT54563.1 - 0.096 12.6 0.1 0.31 11.0 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF438) DapH_N PF08503.10 EMT54564.1 - 1.9e-35 120.9 0.2 5.8e-35 119.4 0.0 1.9 2 0 0 2 2 2 1 Tetrahydrodipicolinate succinyltransferase N-terminal Hexapep PF00132.24 EMT54564.1 - 5.1e-19 67.2 30.0 1.2e-07 31.1 8.1 3.8 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMT54564.1 - 8.5e-13 47.8 33.0 1.2e-08 34.5 5.8 4.3 3 1 1 4 4 4 4 Hexapeptide repeat of succinyl-transferase Acetyltransf_3 PF13302.7 EMT54565.1 - 5.1e-22 79.0 0.0 6.7e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT54565.1 - 3.5e-07 30.5 0.0 4.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EMT54565.1 - 1.9e-06 28.1 0.0 2.1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMT54565.1 - 0.001 18.8 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EcsC PF12787.7 EMT54566.1 - 5.9e-79 265.2 0.0 6.7e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 EcsC protein family DUF4112 PF13430.6 EMT54566.1 - 0.019 15.2 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) DUF1284 PF06935.11 EMT54568.1 - 1.7e-23 82.9 0.0 2.2e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1284) Methyltransf_25 PF13649.6 EMT54569.1 - 7.8e-21 74.6 0.0 2.7e-20 72.8 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT54569.1 - 2e-20 73.2 0.0 4.4e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT54569.1 - 8.7e-20 71.1 0.0 1.2e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMT54569.1 - 1.9e-16 60.6 0.0 5.9e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMT54569.1 - 2.2e-15 56.9 0.0 3.3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EMT54569.1 - 4.4e-07 29.7 0.0 6.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 EMT54569.1 - 5e-07 29.3 0.0 8.8e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EMT54569.1 - 3.7e-06 26.4 0.0 5.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EMT54569.1 - 6.5e-06 26.0 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EMT54569.1 - 8e-06 25.5 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 EMT54569.1 - 1.1e-05 25.1 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DREV PF05219.12 EMT54569.1 - 5.3e-05 22.4 0.0 7.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_9 PF08003.11 EMT54569.1 - 8.4e-05 21.6 0.0 0.00015 20.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 EMT54569.1 - 0.00039 19.9 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EMT54569.1 - 0.00066 19.7 0.0 0.00094 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EMT54569.1 - 0.0062 16.2 0.1 0.042 13.5 0.1 2.1 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.20 EMT54569.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase AdoMet_MTase PF07757.13 EMT54569.1 - 0.041 14.2 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase N2227 PF07942.12 EMT54569.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 N2227-like protein TehB PF03848.14 EMT54569.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB N6_N4_Mtase PF01555.18 EMT54569.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 DNA methylase GCD14 PF08704.10 EMT54569.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit HlyD_D23 PF16576.5 EMT54571.1 - 1.9e-29 102.5 7.8 2.6e-17 62.8 0.3 4.2 2 2 2 4 4 4 4 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EMT54571.1 - 3.2e-28 98.5 9.3 1.9e-14 54.2 0.2 4.7 3 1 2 5 5 5 3 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EMT54571.1 - 4.2e-22 77.7 19.0 5.8e-11 42.1 0.2 5.0 6 0 0 6 6 5 4 Biotin-lipoyl like Biotin_lipoyl PF00364.22 EMT54571.1 - 2.2e-15 56.2 13.2 0.0015 18.3 0.5 5.4 4 0 0 4 4 4 4 Biotin-requiring enzyme HlyD_2 PF12700.7 EMT54571.1 - 4.1e-10 39.0 18.0 5.4e-05 22.1 0.2 4.1 2 2 2 4 4 4 3 HlyD family secretion protein Peptidase_M23 PF01551.22 EMT54571.1 - 1.4e-06 28.4 2.8 0.22 11.8 0.1 4.7 3 1 1 4 4 4 2 Peptidase family M23 PTS_EIIA_1 PF00358.20 EMT54571.1 - 5e-06 26.3 5.8 0.15 11.8 0.0 4.4 4 0 0 4 4 4 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 EMT54571.1 - 6.2e-05 22.9 7.0 0.42 10.6 0.0 5.6 6 0 0 6 6 6 1 RnfC Barrel sandwich hybrid domain HlyD PF00529.20 EMT54571.1 - 0.00013 21.7 0.0 0.00051 19.9 0.0 2.0 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS ProQ_C PF17516.2 EMT54571.1 - 0.00031 20.1 1.7 0.79 9.2 0.1 3.6 3 0 0 3 3 3 2 ProQ C-terminal domain QRPTase_N PF02749.16 EMT54571.1 - 0.0063 16.5 1.5 2.4 8.2 0.0 3.6 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain PYNP_C PF07831.13 EMT54571.1 - 0.092 12.4 1.2 12 5.6 0.0 3.2 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain RTX_C PF08339.10 EMT54571.1 - 0.64 10.1 3.8 3.2 7.8 1.9 2.4 1 1 0 2 2 2 0 RTX C-terminal domain MacB_PCD PF12704.7 EMT54572.1 - 4.5e-12 46.7 0.1 9.3e-10 39.2 0.0 3.2 4 0 0 4 4 4 2 MacB-like periplasmic core domain FtsX PF02687.21 EMT54572.1 - 1.3e-10 41.5 7.8 1.3e-10 41.5 7.8 2.9 3 0 0 3 3 3 1 FtsX-like permease family ABC_tran PF00005.27 EMT54573.1 - 6.6e-36 123.8 0.0 1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMT54573.1 - 5.8e-08 32.4 0.4 1.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMT54573.1 - 5.3e-07 29.8 0.3 0.026 14.3 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EMT54573.1 - 2.9e-05 24.1 0.1 6.4e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EMT54573.1 - 0.00021 20.9 0.1 0.00038 20.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMT54573.1 - 0.00052 20.3 1.2 0.0025 18.1 1.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMT54573.1 - 0.00077 19.3 2.1 0.0025 17.6 0.2 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EMT54573.1 - 0.0015 18.1 0.0 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMT54573.1 - 0.0022 18.4 0.1 0.0037 17.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 EMT54573.1 - 0.0027 17.8 1.5 0.054 13.6 0.3 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EMT54573.1 - 0.0035 17.4 0.3 0.034 14.2 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EMT54573.1 - 0.0036 17.5 0.1 0.0085 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 EMT54573.1 - 0.012 14.7 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_13 PF13166.6 EMT54573.1 - 0.014 14.1 0.1 2.6 6.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EMT54573.1 - 0.021 14.4 0.0 0.046 13.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EMT54573.1 - 0.021 15.4 0.1 0.16 12.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 EMT54573.1 - 0.024 14.0 0.2 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 KaiC SbcCD_C PF13558.6 EMT54573.1 - 0.034 14.4 0.1 0.91 9.8 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 EMT54573.1 - 0.036 13.7 0.0 0.69 9.5 0.0 2.2 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 EMT54573.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EMT54573.1 - 0.046 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EMT54573.1 - 0.054 12.8 0.1 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 EMT54573.1 - 0.081 13.4 2.4 0.15 12.6 2.4 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EMT54573.1 - 0.088 12.7 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EMT54573.1 - 0.11 12.3 0.1 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EMT54573.1 - 0.12 11.6 0.2 1.2 8.3 0.0 1.9 1 1 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.22 EMT54573.1 - 0.12 12.8 0.0 0.61 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 EMT54573.1 - 0.12 12.1 0.2 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EMT54573.1 - 0.12 12.8 1.1 2.3 8.6 1.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EMT54573.1 - 0.14 12.2 0.7 0.2 11.7 0.1 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain Phos_pyr_kin PF08543.12 EMT54575.1 - 2.4e-90 302.2 1.1 2.8e-90 302.0 1.1 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EMT54575.1 - 2e-09 37.2 0.4 3.3e-09 36.5 0.4 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Nitro_FeMo-Co PF02579.17 EMT54575.1 - 0.069 13.5 0.2 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor EamA PF00892.20 EMT54576.1 - 1.9e-27 96.1 43.2 6.8e-16 58.7 17.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family Prion_bPrPp PF11587.8 EMT54576.1 - 0.088 12.7 2.1 6.9 6.6 1.0 3.3 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal EamA PF00892.20 EMT54577.1 - 4e-22 78.9 37.0 1.2e-11 45.0 14.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EMT54577.1 - 3.6e-05 23.3 8.0 3.6e-05 23.3 8.0 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family IncE PF17627.2 EMT54577.1 - 0.68 10.0 9.9 0.035 14.1 3.5 2.2 2 0 0 2 2 2 0 Inclusion membrane protein E Gram_pos_anchor PF00746.21 EMT54577.1 - 2.6 8.1 0.0 2.6 8.1 0.0 3.6 5 0 0 5 5 5 0 LPXTG cell wall anchor motif Tmemb_18A PF09771.9 EMT54577.1 - 3.5 8.0 5.3 1.2 9.5 1.4 2.2 2 1 1 3 3 3 0 Transmembrane protein 188 YfhO PF09586.10 EMT54577.1 - 4.3 5.5 12.3 0.13 10.4 5.2 2.0 2 1 1 3 3 3 0 Bacterial membrane protein YfhO HK PF02110.15 EMT54579.1 - 1.1e-92 309.8 5.8 1.3e-92 309.7 5.8 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 EMT54579.1 - 7.2e-07 28.8 2.0 9.7e-07 28.4 2.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 EMT54579.1 - 5.1e-06 26.2 4.1 8.8e-06 25.4 4.1 1.4 1 1 0 1 1 1 1 Carbohydrate kinase YitT_membrane PF02588.15 EMT54581.1 - 2.5e-45 154.4 10.2 3e-45 154.1 10.2 1.0 1 0 0 1 1 1 1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 ABC_tran PF00005.27 EMT54582.1 - 1.4e-31 109.8 0.1 2.1e-31 109.3 0.1 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EMT54582.1 - 2.8e-21 75.8 0.0 5.2e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EMT54582.1 - 1.2e-09 38.0 0.1 1.6e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMT54582.1 - 2.8e-06 27.6 0.2 3.2e-05 24.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EMT54582.1 - 7e-06 26.1 0.3 6.1e-05 23.0 0.0 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system TniB PF05621.11 EMT54582.1 - 0.00033 20.1 0.3 0.44 9.9 0.1 2.5 2 1 0 2 2 2 2 Bacterial TniB protein AAA_7 PF12775.7 EMT54582.1 - 0.0016 18.0 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 EMT54582.1 - 0.0029 18.0 0.1 0.0053 17.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EMT54582.1 - 0.0029 17.0 0.0 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 EMT54582.1 - 0.0058 16.8 0.7 0.011 15.9 0.1 1.6 2 0 0 2 2 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 EMT54582.1 - 0.0063 16.3 0.4 0.039 13.7 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 EMT54582.1 - 0.021 14.5 0.1 0.045 13.4 0.1 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 EMT54582.1 - 0.022 15.2 0.7 0.39 11.1 0.7 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EMT54582.1 - 0.025 14.5 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EMT54582.1 - 0.026 14.3 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EMT54582.1 - 0.048 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 EMT54582.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 EMT54582.1 - 0.062 13.0 0.3 0.085 12.5 0.3 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 EMT54582.1 - 0.067 13.3 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EMT54582.1 - 0.068 12.1 0.2 0.15 10.9 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain Myosin_head PF00063.21 EMT54582.1 - 0.08 11.1 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Pox_A32 PF04665.12 EMT54582.1 - 0.083 12.3 0.2 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein BPD_transp_1 PF00528.22 EMT54583.1 - 4.8e-31 107.9 17.6 4.8e-31 107.9 17.6 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EMT54583.1 - 3.1e-14 52.7 0.1 3.1e-14 52.7 0.1 3.2 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C DUF5316 PF17247.2 EMT54583.1 - 9 6.4 8.8 7.8 6.6 1.3 3.2 3 1 0 3 3 3 0 Family of unknown function (DUF5316) BPD_transp_1 PF00528.22 EMT54584.1 - 3.1e-39 134.6 15.8 3.1e-39 134.6 15.8 2.0 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 EMT54585.1 - 9.4e-75 251.9 5.4 1.2e-74 251.6 5.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF3899 PF13038.6 EMT54586.1 - 3.4e-09 37.1 0.5 3.4e-09 37.1 0.5 1.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3899) DUF2007 PF09413.10 EMT54588.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 Putative prokaryotic signal transducing protein Glyoxalase PF00903.25 EMT54589.1 - 0.00012 22.3 0.0 0.00059 20.0 0.0 2.1 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EMT54589.1 - 0.0078 16.1 0.0 0.18 11.8 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase-like domain TxDE PF18711.1 EMT54589.1 - 0.037 14.1 0.0 0.089 12.9 0.0 1.7 1 1 0 1 1 1 0 Toxoflavin-degrading enzyme Glyoxalase_6 PF18029.1 EMT54590.1 - 1.4e-08 35.4 0.0 1.8e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EMT54590.1 - 0.00011 22.4 0.0 0.00048 20.3 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acetyltransf_4 PF13420.7 EMT54591.1 - 4.8e-27 95.0 0.0 5.4e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT54591.1 - 1.7e-16 60.5 0.1 2e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EMT54591.1 - 1.3e-12 48.6 0.0 1.5e-12 48.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT54591.1 - 6.3e-10 39.1 0.1 8.7e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT54591.1 - 2.2e-08 34.4 0.2 3.9e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT54591.1 - 1.7e-05 24.7 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EMT54591.1 - 4.4e-05 23.6 0.1 0.00015 21.9 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EMT54591.1 - 0.0043 16.7 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 EMT54591.1 - 0.057 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GrpB PF04229.14 EMT54592.1 - 8.4e-53 178.8 0.1 9.4e-53 178.7 0.1 1.0 1 0 0 1 1 1 1 GrpB protein MHB PF16525.5 EMT54592.1 - 0.024 14.9 0.4 0.82 10.0 0.1 2.2 1 1 1 2 2 2 0 Haemophore, haem-binding MarR_2 PF12802.7 EMT54593.1 - 7.3e-15 54.6 0.2 1.3e-14 53.8 0.2 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EMT54593.1 - 7.8e-13 48.2 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EMT54593.1 - 2.8e-08 34.1 0.2 5.5e-08 33.2 0.1 1.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EMT54593.1 - 0.00076 19.0 0.1 0.0019 17.7 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HxlR PF01638.17 EMT54593.1 - 0.0031 17.3 0.1 0.0055 16.5 0.1 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix Fe_dep_repress PF01325.19 EMT54593.1 - 0.0085 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_1 PF00126.27 EMT54593.1 - 0.0098 15.8 1.0 0.017 15.0 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family KORA PF16509.5 EMT54593.1 - 0.026 14.8 0.1 0.052 13.8 0.1 1.5 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor GntR PF00392.21 EMT54593.1 - 0.068 12.8 0.3 0.17 11.6 0.3 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family VirE PF05272.11 EMT54593.1 - 0.073 12.8 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 Virulence-associated protein E HTH_Crp_2 PF13545.6 EMT54593.1 - 0.077 13.0 1.9 0.2 11.6 1.2 2.1 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_34 PF13601.6 EMT54593.1 - 0.091 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain YdaS_antitoxin PF15943.5 EMT54593.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF3665 PF12427.8 EMT54593.1 - 0.17 11.6 1.1 0.34 10.6 1.1 1.5 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase MFS_1 PF07690.16 EMT54594.1 - 1.3e-64 218.4 91.6 1.5e-52 178.7 57.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT54594.1 - 1.1e-07 31.1 12.1 6.4e-06 25.3 9.4 3.3 3 1 1 4 4 4 2 MFS_1 like family Sugar_tr PF00083.24 EMT54594.1 - 2e-06 27.0 8.4 2e-06 27.0 8.4 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter DUF1146 PF06612.11 EMT54594.1 - 0.0025 17.8 0.1 0.0025 17.8 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1146) PUCC PF03209.15 EMT54594.1 - 0.0054 15.8 13.5 0.0054 15.8 13.5 3.1 2 1 1 3 3 3 2 PUCC protein OATP PF03137.20 EMT54594.1 - 0.035 12.4 18.9 0.39 9.0 2.1 3.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GWT1 PF06423.12 EMT54594.1 - 0.84 9.8 3.9 0.74 9.9 0.1 2.7 3 1 0 3 3 3 0 GWT1 DUF2627 PF11118.8 EMT54594.1 - 4.6 7.9 7.5 2.5 8.7 2.3 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) GDC-P PF02347.16 EMT54595.1 - 2.4e-12 46.4 0.0 3.9e-10 39.1 0.0 2.0 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EMT54595.1 - 5.4e-05 22.3 0.0 8.1e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMT54595.1 - 0.0043 16.4 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 EMT54596.1 - 7.2e-139 463.3 0.0 8.9e-139 463.0 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein PELOTA_1 PF15608.6 EMT54596.1 - 0.026 14.4 0.2 0.065 13.1 0.2 1.6 1 0 0 1 1 1 0 PELOTA RNA binding domain LysR_substrate PF03466.20 EMT54597.1 - 1.1e-52 178.5 0.0 1.4e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT54597.1 - 1e-22 79.8 0.1 2e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 EMT54597.1 - 0.024 14.5 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 EMT54597.1 - 0.073 12.6 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Thioredoxin_3 PF13192.6 EMT54598.1 - 3.1e-07 30.3 0.0 3.3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain Glutaredoxin PF00462.24 EMT54598.1 - 0.00017 21.7 0.0 0.00025 21.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 EMT54598.1 - 0.00038 20.4 0.0 0.00043 20.2 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 EMT54598.1 - 0.0075 16.4 0.1 0.078 13.1 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin Phos_pyr_kin PF08543.12 EMT54599.1 - 1.9e-86 289.5 0.1 2.1e-86 289.3 0.1 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EMT54599.1 - 4.1e-10 39.5 0.0 6.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Aminotran_5 PF00266.19 EMT54600.1 - 4.1e-143 476.8 0.0 4.6e-143 476.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMT54600.1 - 8.9e-08 31.7 0.0 1.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMT54600.1 - 1.8e-06 27.5 0.9 1.3e-05 24.7 0.7 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EMT54600.1 - 7.9e-06 25.4 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EMT54600.1 - 1.6e-05 23.7 0.0 2.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ThiC_Rad_SAM PF01964.18 EMT54602.1 - 1.4e-205 682.9 0.0 1.7e-205 682.6 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 EMT54602.1 - 1.3e-29 101.8 0.1 3e-29 100.7 0.1 1.6 1 0 0 1 1 1 1 ThiC-associated domain DUF1192 PF06698.11 EMT54603.1 - 0.058 13.5 0.8 0.079 13.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) PEP-utilisers_N PF05524.13 EMT54603.1 - 0.059 13.6 0.0 0.063 13.5 0.0 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal T3SS_needle_E PF08988.10 EMT54603.1 - 0.066 13.4 0.2 0.082 13.1 0.2 1.2 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle AHSA1 PF08327.11 EMT54604.1 - 3.4e-12 46.7 0.0 3.8e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EMT54604.1 - 0.072 13.4 0.0 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ABM PF03992.16 EMT54605.1 - 2.5e-07 30.7 0.0 3.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.6 EMT54605.1 - 0.0001 22.6 0.1 0.00018 21.8 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 EMT54605.1 - 0.008 15.6 0.3 0.0092 15.4 0.3 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase TusA PF01206.17 EMT54605.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Sulfurtransferase TusA MAGE PF01454.19 EMT54606.1 - 0.024 14.3 0.6 0.027 14.2 0.6 1.0 1 0 0 1 1 1 0 MAGE family UTRA PF07702.13 EMT54607.1 - 5.9e-34 116.9 0.0 1.6e-32 112.3 0.0 2.0 2 0 0 2 2 2 1 UTRA domain GntR PF00392.21 EMT54607.1 - 7.1e-17 60.8 0.0 1.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EMT54607.1 - 7e-05 22.3 0.1 0.0002 20.9 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_41 PF14502.6 EMT54607.1 - 8.8e-05 22.1 0.2 0.00019 21.0 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 EMT54607.1 - 0.00022 21.1 0.9 0.00054 19.8 0.1 2.1 3 0 0 3 3 3 1 HTH domain HTH_Crp_2 PF13545.6 EMT54607.1 - 0.0011 18.9 0.1 0.0038 17.2 0.0 1.9 2 0 0 2 2 1 1 Crp-like helix-turn-helix domain HTH_36 PF13730.6 EMT54607.1 - 0.0017 18.3 0.1 0.0037 17.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EMT54607.1 - 0.0024 17.7 0.1 0.034 14.0 0.0 2.5 3 0 0 3 3 3 1 MarR family HTH_28 PF13518.6 EMT54607.1 - 0.0043 17.1 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 EMT54607.1 - 0.0051 16.3 0.2 0.022 14.2 0.1 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 AbiEi_4 PF13338.6 EMT54607.1 - 0.0087 16.2 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin DUF746 PF05344.11 EMT54607.1 - 0.011 15.6 0.1 1.2 9.0 0.1 3.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF746) MarR PF01047.22 EMT54607.1 - 0.011 15.7 0.1 0.12 12.3 0.1 2.3 2 0 0 2 2 2 0 MarR family Phage_rep_O PF04492.13 EMT54607.1 - 0.015 15.9 0.0 0.043 14.4 0.0 1.7 2 0 0 2 2 1 0 Bacteriophage replication protein O DUF1670 PF07900.11 EMT54607.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) Linker_histone PF00538.19 EMT54607.1 - 0.032 14.6 0.1 0.087 13.2 0.1 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family Fe_dep_repress PF01325.19 EMT54607.1 - 0.035 14.3 0.0 0.2 11.8 0.0 2.3 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain HTH_29 PF13551.6 EMT54607.1 - 0.038 14.0 0.0 0.17 11.9 0.0 2.0 3 0 0 3 3 2 0 Winged helix-turn helix HTH_DeoR PF08220.12 EMT54607.1 - 0.077 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_5 PF01022.20 EMT54607.1 - 0.081 12.8 0.5 0.58 10.1 0.0 2.3 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family RbsD_FucU PF05025.13 EMT54608.1 - 3e-38 131.3 0.0 3.5e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family Arc_PepC PF06819.11 EMT54608.1 - 0.0065 16.6 0.1 0.0097 16.0 0.1 1.3 1 0 0 1 1 1 1 Archaeal Peptidase A24 C-terminal Domain Peripla_BP_4 PF13407.6 EMT54609.1 - 3.6e-60 203.7 17.7 4.3e-60 203.5 17.7 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 EMT54609.1 - 8.1e-19 68.1 2.0 1e-18 67.8 2.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_6 PF13458.6 EMT54609.1 - 2.9e-07 30.5 7.4 3.9e-07 30.1 6.2 1.7 1 1 1 2 2 2 1 Periplasmic binding protein Peripla_BP_3 PF13377.6 EMT54609.1 - 5.5e-07 30.1 0.1 9.4e-06 26.1 0.1 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain ATPgrasp_N PF18130.1 EMT54609.1 - 0.038 14.5 3.1 1.7 9.2 0.4 3.4 2 2 1 3 3 3 0 ATP-grasp N-terminal domain PCP_red PF08369.10 EMT54609.1 - 0.26 11.5 1.1 0.98 9.7 0.0 2.3 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit ADH_zinc_N PF00107.26 EMT54609.1 - 1.4 8.9 7.1 10 6.1 0.1 3.3 2 1 1 3 3 3 0 Zinc-binding dehydrogenase BPD_transp_2 PF02653.16 EMT54610.1 - 3.2e-48 164.2 41.9 3.2e-48 164.2 41.9 1.7 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component MS_channel PF00924.18 EMT54610.1 - 1.6 8.3 9.8 3.9 7.0 9.8 1.7 1 0 0 1 1 1 0 Mechanosensitive ion channel ABC_tran PF00005.27 EMT54611.1 - 2.5e-52 177.0 1.3 3.7e-33 114.9 0.1 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMT54611.1 - 5.9e-09 36.1 0.7 0.0049 16.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EMT54611.1 - 0.00016 21.6 0.4 0.0014 18.5 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EMT54611.1 - 0.00074 19.2 0.3 0.0028 17.3 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 EMT54611.1 - 0.0013 19.2 2.3 0.1 13.0 2.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EMT54611.1 - 0.0014 18.4 3.3 0.005 16.6 0.9 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EMT54611.1 - 0.0023 17.9 0.5 1.7 8.7 0.0 3.0 2 1 1 3 3 3 1 AAA domain SMC_N PF02463.19 EMT54611.1 - 0.0031 17.0 2.1 0.044 13.2 0.8 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain MeaB PF03308.16 EMT54611.1 - 0.0069 15.4 0.2 0.26 10.2 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EMT54611.1 - 0.0089 16.6 0.8 0.016 15.7 0.1 1.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EMT54611.1 - 0.011 15.1 0.1 0.025 13.8 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EMT54611.1 - 0.014 15.7 0.7 0.11 12.8 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 EMT54611.1 - 0.017 15.2 0.1 1.7 8.8 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_27 PF13514.6 EMT54611.1 - 0.018 14.6 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EMT54611.1 - 0.037 13.2 0.1 0.16 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 EMT54611.1 - 0.068 13.2 0.3 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EMT54611.1 - 0.085 12.4 0.1 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EMT54611.1 - 0.11 12.2 0.8 0.69 9.6 0.1 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EMT54611.1 - 0.12 12.6 1.4 1.3 9.3 0.7 2.7 2 1 0 2 2 2 0 AAA domain PfkB PF00294.24 EMT54612.1 - 1e-65 222.1 0.0 1.1e-65 221.9 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EMT54612.1 - 6.4e-12 45.4 0.1 9.8e-12 44.8 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 EMT54612.1 - 0.0001 21.9 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate kinase Vac_Fusion PF02346.16 EMT54612.1 - 0.0013 18.3 0.1 0.0023 17.5 0.1 1.3 1 0 0 1 1 1 1 Chordopoxvirus multifunctional envelope protein A27 DeoC PF01791.9 EMT54613.1 - 1e-12 48.2 1.0 1.3e-12 47.9 1.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase NanE PF04131.14 EMT54613.1 - 0.0013 17.9 0.2 0.0021 17.3 0.2 1.3 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 EMT54613.1 - 0.0061 16.1 0.3 0.013 15.0 0.3 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 EMT54613.1 - 0.0069 15.6 0.3 0.072 12.3 0.1 2.1 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EMT54613.1 - 0.022 13.8 0.3 0.043 12.8 0.3 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF455 PF04305.14 EMT54614.1 - 1.5e-13 50.8 0.2 3.4e-13 49.7 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF455) AP_endonuc_2 PF01261.24 EMT54615.1 - 2.1e-05 24.1 0.0 6.2e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Bactofilin PF04519.13 EMT54616.1 - 8.4e-13 48.4 13.6 1.5e-08 34.8 3.2 3.3 2 1 1 3 3 3 2 Polymer-forming cytoskeletal DUF5115 PF17142.4 EMT54616.1 - 0.06 13.0 0.2 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5115) Candida_ALS_N PF11766.8 EMT54616.1 - 0.06 12.6 0.6 0.094 12.0 0.6 1.2 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding DUF2807 PF10988.8 EMT54616.1 - 0.74 9.6 13.1 0.55 10.0 7.8 2.7 2 1 1 3 3 3 0 Putative auto-transporter adhesin, head GIN domain DUF4004 PF13171.6 EMT54617.1 - 5.3e-83 278.1 2.3 6e-83 277.9 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4004) HTH_26 PF13443.6 EMT54617.1 - 0.016 15.7 0.1 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_28 PF13518.6 EMT54617.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 EMT54617.1 - 0.07 13.2 0.0 0.51 10.5 0.0 2.3 1 1 1 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain GGDEF PF00990.21 EMT54619.1 - 1e-48 165.1 0.2 1.5e-48 164.6 0.2 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 EMT54619.1 - 3.4e-07 30.5 0.1 7.1e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 PAS domain GGDEF_2 PF17853.1 EMT54619.1 - 0.0018 18.5 0.1 0.0036 17.6 0.1 1.4 1 0 0 1 1 1 1 GGDEF-like domain PAS_8 PF13188.7 EMT54619.1 - 0.0025 17.8 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EMT54619.1 - 0.0067 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EMT54619.1 - 0.0096 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold DUF1697 PF08002.11 EMT54621.1 - 1.7e-45 154.8 0.1 9e-45 152.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1697) Putative_PNPOx PF01243.20 EMT54622.1 - 1.9e-15 56.8 0.0 2.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Monooxygenase_B PF04744.12 EMT54623.1 - 0.0093 14.8 0.1 0.093 11.5 0.1 1.9 1 1 1 2 2 2 2 Monooxygenase subunit B protein DUF4971 PF16341.5 EMT54623.1 - 0.045 13.6 0.1 0.086 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) Arch_flagellin PF01917.16 EMT54623.1 - 0.081 13.1 0.4 0.12 12.6 0.4 1.4 1 1 0 1 1 1 0 Archaebacterial flagellin Transp_inhibit PF18791.1 EMT54624.1 - 0.22 11.0 1.3 2.6 7.6 0.2 2.3 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain Acetyltransf_1 PF00583.25 EMT54625.1 - 9.3e-12 45.2 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMT54625.1 - 3.2e-11 43.2 0.1 4.3e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT54625.1 - 4.5e-09 36.6 0.0 7.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT54625.1 - 0.00094 19.3 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EMT54625.1 - 0.0018 18.2 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 EMT54625.1 - 0.0071 16.1 0.0 0.0087 15.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 EMT54625.1 - 0.009 16.1 0.2 0.14 12.2 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EMT54625.1 - 0.013 15.0 0.1 0.014 14.9 0.1 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 EMT54625.1 - 0.045 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_16 PF05301.11 EMT54625.1 - 0.079 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Epimerase PF01370.21 EMT54626.1 - 9.9e-25 87.4 0.1 1.4e-24 86.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMT54626.1 - 8.1e-20 71.5 0.2 1.2e-19 70.9 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMT54626.1 - 9.9e-13 48.2 0.2 2.6e-12 46.8 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EMT54626.1 - 2.7e-12 46.7 0.0 3.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMT54626.1 - 4.1e-08 32.6 0.0 6.1e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EMT54626.1 - 1.8e-07 30.6 0.1 2e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EMT54626.1 - 0.0024 17.1 2.2 1 8.5 0.1 3.0 1 1 1 2 2 2 2 Male sterility protein adh_short_C2 PF13561.6 EMT54626.1 - 0.01 15.4 0.3 0.26 10.8 0.1 2.8 4 0 0 4 4 4 0 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 EMT54626.1 - 0.012 15.8 0.1 0.028 14.7 0.1 1.6 1 1 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 EMT54626.1 - 0.013 15.1 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.26 EMT54626.1 - 0.019 14.9 0.2 0.054 13.5 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.25 EMT54626.1 - 0.069 12.6 1.3 0.2 11.1 0.2 2.1 3 0 0 3 3 3 0 short chain dehydrogenase Glyco_trans_4_4 PF13579.6 EMT54626.1 - 0.085 13.3 0.2 0.23 11.9 0.1 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Pyr_redox PF00070.27 EMT54626.1 - 0.086 13.4 0.7 0.23 12.1 0.3 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 EMT54626.1 - 0.14 12.8 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HxlR PF01638.17 EMT54627.1 - 2.2e-33 114.0 0.0 2.6e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_20 PF12840.7 EMT54627.1 - 0.00038 20.5 0.0 0.00062 19.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 EMT54627.1 - 0.00068 19.1 0.1 0.0012 18.3 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 EMT54627.1 - 0.0012 18.7 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_12 PF08461.10 EMT54627.1 - 0.0012 18.7 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain PadR PF03551.14 EMT54627.1 - 0.0035 17.3 0.1 0.0048 16.8 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_Crp_2 PF13545.6 EMT54627.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 EMT54627.1 - 0.024 14.6 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 MarR family Replic_Relax PF13814.6 EMT54627.1 - 0.026 14.6 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation MarR_2 PF12802.7 EMT54627.1 - 0.063 13.2 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_34 PF13601.6 EMT54627.1 - 0.1 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain 60KD_IMP PF02096.20 EMT54628.1 - 3.2e-36 124.7 5.7 3.9e-36 124.4 5.7 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein EMC3_TMCO1 PF01956.16 EMT54628.1 - 0.083 12.6 3.8 0.14 11.9 3.6 1.7 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like 5_nucleotid_C PF02872.18 EMT54629.1 - 6.8e-25 88.1 0.1 1.3e-24 87.2 0.1 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EMT54629.1 - 2.8e-13 50.8 0.1 4.2e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 EMT54629.1 - 0.00081 18.9 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Peptidase_M20 PF01546.28 EMT54630.1 - 5.2e-07 29.6 0.3 9.5e-07 28.7 0.3 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT54630.1 - 0.00053 19.9 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain ScsC_N PF18312.1 EMT54630.1 - 0.081 12.8 1.7 0.26 11.2 1.7 1.9 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Peptidase_M20 PF01546.28 EMT54631.1 - 4e-21 75.7 1.5 5.9e-21 75.1 1.5 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMT54631.1 - 3.6e-14 52.6 1.2 6.5e-14 51.8 1.2 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain ABG_transport PF03806.13 EMT54632.1 - 5e-183 608.9 36.1 5.7e-183 608.7 36.1 1.0 1 0 0 1 1 1 1 AbgT putative transporter family DUF2116 PF09889.9 EMT54632.1 - 2.1 8.4 0.0 2.1 8.4 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TssO PF17561.2 EMT54632.1 - 4.7 7.3 5.2 4.4 7.4 0.4 2.8 2 0 0 2 2 2 0 Type VI secretion system, TssO SBP_bac_3 PF00497.20 EMT54633.1 - 0.0079 15.6 0.2 0.018 14.5 0.2 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peptidase_S58 PF03576.14 EMT54634.1 - 2e-57 195.0 16.7 2.7e-57 194.6 16.7 1.1 1 0 0 1 1 1 1 Peptidase family S58 TAT_signal PF10518.9 EMT54634.1 - 0.018 14.9 0.2 0.018 14.9 0.2 3.7 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence DUF4350 PF14258.6 EMT54634.1 - 0.11 13.0 0.0 1.4 9.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) HTH_17 PF12728.7 EMT54635.1 - 1.6e-08 34.6 0.0 3.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain TM_helix PF05552.12 EMT54635.1 - 2.7 8.1 6.0 6 6.9 6.0 1.5 1 0 0 1 1 1 0 Conserved TM helix PNKP_ligase PF16542.5 EMT54636.1 - 1.1e-25 90.8 0.0 1.8e-24 86.8 0.0 2.5 1 1 0 1 1 1 1 PNKP adenylyltransferase domain, ligase domain Metallophos PF00149.28 EMT54636.1 - 7.9e-07 29.8 0.2 1.9e-06 28.5 0.2 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA_33 PF13671.6 EMT54636.1 - 1.4e-05 25.3 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Metallophos_2 PF12850.7 EMT54636.1 - 1.8e-05 25.0 0.6 4.8e-05 23.6 0.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_14 PF13173.6 EMT54636.1 - 0.0038 17.3 0.0 0.036 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_ligase PF09414.10 EMT54636.1 - 0.017 15.4 3.7 0.15 12.4 0.0 3.8 3 2 0 3 3 3 0 RNA ligase AAA PF00004.29 EMT54636.1 - 0.043 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 EMT54636.1 - 0.094 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit PduV-EutP PF10662.9 EMT54636.1 - 0.16 11.7 0.0 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Methyltransf_25 PF13649.6 EMT54637.1 - 5.1e-10 39.9 0.1 1.5e-09 38.4 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMT54637.1 - 5.9e-10 39.1 0.2 9.4e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMT54637.1 - 4.3e-06 27.3 0.0 8.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMT54637.1 - 7.2e-06 25.6 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EMT54637.1 - 1.2e-05 25.9 0.7 4.1e-05 24.2 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EMT54637.1 - 0.00011 21.8 0.0 0.00022 20.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EMT54637.1 - 0.00045 20.1 0.1 0.0014 18.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EMT54637.1 - 0.0043 16.0 0.0 0.011 14.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 EMT54637.1 - 0.0045 16.5 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 EMT54637.1 - 0.0086 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain L51_S25_CI-B8 PF05047.16 EMT54637.1 - 0.016 15.1 0.0 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Imm8 PF15586.6 EMT54637.1 - 0.096 12.7 0.1 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 8 MetW PF07021.12 EMT54637.1 - 0.11 12.0 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF4087 PF13316.6 EMT54637.1 - 0.14 12.7 0.0 0.69 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4087) PCMT PF01135.19 EMT54637.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TROVE PF05731.11 EMT54638.1 - 2.1e-15 56.7 0.0 3e-12 46.3 0.1 2.2 1 1 1 2 2 2 2 TROVE domain DUF2201 PF09967.9 EMT54638.1 - 0.00061 19.9 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 VWA-like domain (DUF2201) VWA_CoxE PF05762.14 EMT54638.1 - 0.00083 18.8 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 EMT54638.1 - 0.0027 18.3 1.2 0.021 15.4 0.0 3.1 4 1 0 4 4 4 1 von Willebrand factor type A domain WYL PF13280.6 EMT54639.1 - 1.8e-32 112.8 1.8 2.7e-32 112.2 1.8 1.3 1 0 0 1 1 1 1 WYL domain HTH_DeoR PF08220.12 EMT54639.1 - 0.00021 21.0 0.1 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 EMT54639.1 - 0.00044 20.3 0.2 0.88 9.7 0.0 3.0 3 0 0 3 3 3 2 Helix-turn-helix domain Mga PF05043.13 EMT54639.1 - 0.00097 19.7 0.1 0.0034 17.9 0.1 1.9 1 0 0 1 1 1 1 Mga helix-turn-helix domain HTH_11 PF08279.12 EMT54639.1 - 0.0043 17.0 2.7 0.21 11.6 0.1 3.3 3 0 0 3 3 3 1 HTH domain TrmB PF01978.19 EMT54639.1 - 0.007 16.2 0.1 2.8 7.9 0.1 2.6 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 EMT54639.1 - 0.008 16.0 0.2 0.038 13.8 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain Penicillinase_R PF03965.16 EMT54639.1 - 0.032 14.6 0.0 0.14 12.5 0.0 2.1 1 1 0 1 1 1 0 Penicillinase repressor HTH_30 PF13556.6 EMT54639.1 - 0.033 14.0 0.1 0.079 12.8 0.1 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain WYL PF13280.6 EMT54640.1 - 7.6e-15 55.4 3.4 1e-14 55.0 3.4 1.2 1 0 0 1 1 1 1 WYL domain EutC PF05985.11 EMT54640.1 - 0.034 13.4 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) HATPase_c PF02518.26 EMT54641.1 - 3.5e-21 75.8 0.0 2.4e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 5TM-5TMR_LYT PF07694.12 EMT54641.1 - 1.8e-12 47.1 11.2 2.9e-12 46.4 11.2 1.2 1 0 0 1 1 1 1 5TMR of 5TMR-LYT HisKA PF00512.25 EMT54641.1 - 1e-11 44.7 0.2 5.1e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 EMT54641.1 - 1.1e-07 31.7 0.0 2.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 EMT54641.1 - 1.1e-05 25.3 0.1 2.5e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMT54641.1 - 0.0079 16.2 0.1 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain 2-Hacid_dh_C PF02826.19 EMT54642.1 - 5.9e-65 217.9 0.0 8.8e-65 217.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMT54642.1 - 1.9e-30 105.2 0.0 2.2e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMT54642.1 - 2.7e-09 37.4 0.0 2.6e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EMT54642.1 - 0.00092 19.8 0.0 0.002 18.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EMT54642.1 - 0.0019 17.8 0.0 0.0048 16.5 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain PDEase_II PF02112.15 EMT54642.1 - 0.052 12.6 0.0 0.074 12.1 0.0 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II PdxA PF04166.12 EMT54643.1 - 1.2e-108 362.9 0.1 1.4e-108 362.6 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA HGD-D PF06050.13 EMT54643.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component TPR_8 PF13181.6 EMT54643.1 - 0.32 11.3 1.4 32 5.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fe-ADH PF00465.19 EMT54644.1 - 1.5e-117 392.5 0.4 1.8e-117 392.3 0.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMT54644.1 - 4.5e-18 65.9 0.2 3.3e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Toprim PF01751.22 EMT54644.1 - 0.078 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Toprim domain Aldedh PF00171.22 EMT54645.1 - 2.3e-159 530.8 1.1 2.7e-159 530.6 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EMT54645.1 - 0.0069 15.5 0.0 0.063 12.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Lar_N PF09861.9 EMT54646.1 - 2.6e-10 39.8 0.4 4.1e-10 39.2 0.4 1.2 1 0 0 1 1 1 1 Lactate racemase N-terminal domain DUF362 PF04015.12 EMT54646.1 - 1.3e-05 25.5 0.1 2.1e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF362) DctM PF06808.12 EMT54647.1 - 2.1e-126 422.1 56.0 2.4e-126 421.9 56.0 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component CitMHS PF03600.16 EMT54647.1 - 7.8e-05 22.0 63.7 0.014 14.6 30.7 2.1 1 1 1 2 2 2 2 Citrate transporter DcuC PF03606.15 EMT54647.1 - 0.0019 16.7 44.9 0.0031 16.0 18.7 3.1 1 1 1 2 2 2 2 C4-dicarboxylate anaerobic carrier PRA1 PF03208.19 EMT54647.1 - 0.02 14.5 1.8 0.02 14.5 1.8 4.3 2 2 0 3 3 3 0 PRA1 family protein End_beta_barrel PF12195.8 EMT54647.1 - 0.03 14.3 0.8 0.075 13.0 0.8 1.6 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase MLANA PF14991.6 EMT54647.1 - 0.037 14.3 0.2 0.037 14.3 0.2 2.3 2 1 1 3 3 3 0 Protein melan-A DctQ PF04290.12 EMT54648.1 - 8.6e-31 106.6 10.7 8.6e-31 106.6 10.7 1.3 1 1 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component TIP49_C PF17856.1 EMT54648.1 - 0.041 14.0 0.4 3.9 7.7 0.0 2.4 2 0 0 2 2 2 0 TIP49 AAA-lid domain MttA_Hcf106 PF02416.16 EMT54648.1 - 0.053 12.9 0.6 0.15 11.4 0.6 1.8 1 0 0 1 1 1 0 mttA/Hcf106 family DUF4389 PF14333.6 EMT54648.1 - 0.36 10.8 13.5 0.14 12.1 1.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) Colicin_V PF02674.16 EMT54648.1 - 1.9 8.5 12.7 1.5 8.7 11.0 1.7 1 1 1 2 2 2 0 Colicin V production protein Abhydrolase_9_N PF15420.6 EMT54648.1 - 6.2 6.8 12.3 6.7 6.6 5.6 1.8 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DctP PF03480.13 EMT54649.1 - 4.5e-103 344.5 0.3 5.2e-103 344.3 0.3 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 SBP_bac_3 PF00497.20 EMT54649.1 - 0.016 14.6 0.0 0.12 11.8 0.0 2.2 2 1 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 ArgoMid PF16487.5 EMT54649.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Mid domain of argonaute SBD_N PF07005.11 EMT54650.1 - 3.3e-67 226.6 0.3 4.8e-67 226.0 0.3 1.2 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 EMT54650.1 - 3.2e-29 102.6 0.7 1.3e-28 100.6 0.1 2.0 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain Arena_ncap_C PF17290.2 EMT54650.1 - 0.042 13.2 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain PrpR_N PF06506.11 EMT54651.1 - 1.2e-53 181.1 0.2 3.2e-53 179.7 0.2 1.7 1 0 0 1 1 1 1 Propionate catabolism activator Sigma54_activat PF00158.26 EMT54651.1 - 4.7e-43 146.8 0.0 8.8e-43 145.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EMT54651.1 - 2.6e-16 60.0 0.0 1.2e-15 57.9 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain HTH_8 PF02954.19 EMT54651.1 - 1.9e-14 53.2 1.2 5.9e-14 51.6 1.2 1.9 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family PAS PF00989.25 EMT54651.1 - 8.8e-08 32.1 0.0 2.6e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 PAS fold AAA_5 PF07728.14 EMT54651.1 - 1.1e-07 31.9 0.0 6e-07 29.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMT54651.1 - 6.9e-06 25.6 0.2 0.1 12.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EMT54651.1 - 1.6e-05 24.7 0.0 0.014 15.2 0.0 3.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 EMT54651.1 - 3.2e-05 23.1 0.0 0.00014 21.1 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain HTH_23 PF13384.6 EMT54651.1 - 9.5e-05 22.1 0.2 0.00023 20.8 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain AAA PF00004.29 EMT54651.1 - 0.0002 21.8 0.1 0.0014 19.1 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EMT54651.1 - 0.00031 20.5 0.0 0.00073 19.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein HTH_38 PF13936.6 EMT54651.1 - 0.00039 20.1 0.5 0.00093 18.9 0.5 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 EMT54651.1 - 0.00049 19.6 0.2 0.0016 17.9 0.2 2.0 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AAA_16 PF13191.6 EMT54651.1 - 0.00051 20.5 0.0 0.0018 18.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PAS_4 PF08448.10 EMT54651.1 - 0.00061 20.0 0.0 0.0018 18.5 0.0 1.9 1 0 0 1 1 1 1 PAS fold Sigma70_r4 PF04545.16 EMT54651.1 - 0.00077 18.9 0.3 0.0019 17.7 0.3 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 PAS_8 PF13188.7 EMT54651.1 - 0.0011 18.9 0.0 0.0039 17.2 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 EMT54651.1 - 0.0024 18.1 0.0 0.016 15.5 0.0 2.4 2 0 0 2 2 1 1 PAS domain AAA_7 PF12775.7 EMT54651.1 - 0.0036 16.8 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 EMT54651.1 - 0.0044 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EMT54651.1 - 0.0059 16.5 0.0 0.074 13.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain PAS_7 PF12860.7 EMT54651.1 - 0.0059 16.8 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold HTH_Tnp_ISL3 PF13542.6 EMT54651.1 - 0.0077 15.6 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_psq PF05225.16 EMT54651.1 - 0.0079 15.9 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_30 PF13556.6 EMT54651.1 - 0.015 15.1 0.0 0.08 12.8 0.0 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 EMT54651.1 - 0.02 14.9 0.1 0.054 13.5 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 EMT54651.1 - 0.033 14.3 0.1 0.085 13.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 EMT54651.1 - 0.034 14.2 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 1 0 Helix-turn-helix domain of resolvase Bac_DnaA PF00308.18 EMT54651.1 - 0.037 13.9 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein KORA PF16509.5 EMT54651.1 - 0.047 14.0 0.2 0.47 10.8 0.1 2.4 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor DUF134 PF02001.16 EMT54651.1 - 0.054 14.1 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF134 DUF815 PF05673.13 EMT54651.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HTH_10 PF04967.12 EMT54651.1 - 0.068 13.0 0.2 1.8 8.5 0.1 2.8 2 0 0 2 2 2 0 HTH DNA binding domain ATPase_2 PF01637.18 EMT54651.1 - 0.068 13.1 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma70_r4_2 PF08281.12 EMT54651.1 - 0.09 12.5 0.1 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 AAA_22 PF13401.6 EMT54651.1 - 0.093 13.0 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 1 0 AAA domain HTH_50 PF18024.1 EMT54651.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 EMT54651.1 - 0.12 12.1 0.1 1.9 8.2 0.0 2.7 3 0 0 3 3 2 0 CENP-B N-terminal DNA-binding domain Phage_NinH PF06322.11 EMT54651.1 - 0.16 11.8 0.1 0.87 9.5 0.0 2.1 2 0 0 2 2 2 0 Phage NinH protein Ion_trans_2 PF07885.16 EMT54652.1 - 2e-16 59.7 8.1 3.1e-16 59.1 8.1 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EMT54652.1 - 0.1 11.8 4.7 0.17 11.1 4.7 1.5 1 1 0 1 1 1 0 Ion transport protein SpoIIP PF07454.11 EMT54653.1 - 8.5e-61 205.7 0.1 1.1e-60 205.3 0.1 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) SH3_3 PF08239.11 EMT54653.1 - 3.4e-39 132.9 9.6 9.4e-14 51.4 0.4 4.5 4 0 0 4 4 4 4 Bacterial SH3 domain SH3_4 PF06347.13 EMT54653.1 - 3.8e-26 90.7 1.1 9.6e-07 28.5 0.3 4.4 4 0 0 4 4 4 3 Bacterial SH3 domain GW PF13457.6 EMT54653.1 - 0.0011 19.5 9.4 0.013 16.1 0.2 3.9 3 0 0 3 3 3 2 GW (Gly-Tryp) dipeptide domain SH3_16 PF18348.1 EMT54653.1 - 0.0017 18.1 0.0 11 6.0 0.0 3.6 3 0 0 3 3 3 2 Bacterial dipeptidyl-peptidase Sh3 domain DUF4453 PF14627.6 EMT54653.1 - 0.039 14.1 0.7 0.27 11.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4453) PSA_CBD PF18341.1 EMT54653.1 - 0.059 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 PSA endolysin C-terminal cell wall binding domain Sigma70_r4_2 PF08281.12 EMT54654.1 - 5e-15 54.9 0.5 1.2e-14 53.7 0.4 1.7 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT54654.1 - 7.9e-14 50.9 3.8 1.3e-13 50.2 0.9 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EMT54654.1 - 1e-13 50.8 0.0 4.2e-13 48.9 0.1 2.0 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 EMT54654.1 - 3.2e-06 27.1 0.4 3.8e-06 26.9 0.4 1.3 1 1 0 1 1 1 1 ECF sigma factor DUF134 PF02001.16 EMT54654.1 - 0.00038 21.0 0.1 0.00074 20.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF134 UPF0122 PF04297.14 EMT54654.1 - 0.00039 20.6 0.4 0.00098 19.3 0.1 1.7 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_11 PF08279.12 EMT54654.1 - 0.001 19.0 0.1 0.0026 17.7 0.1 1.6 1 0 0 1 1 1 1 HTH domain HTH_10 PF04967.12 EMT54654.1 - 0.0085 15.9 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 HTH DNA binding domain HTH_23 PF13384.6 EMT54654.1 - 0.013 15.2 0.9 0.032 14.0 0.5 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_17 PF12728.7 EMT54654.1 - 0.016 15.4 0.1 0.053 13.7 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 EMT54654.1 - 0.017 14.6 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Phage_antitermQ PF06530.12 EMT54654.1 - 0.023 14.6 0.2 0.044 13.7 0.2 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q HTH_29 PF13551.6 EMT54654.1 - 0.069 13.2 0.4 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 EMT54654.1 - 0.087 13.0 0.7 0.22 11.7 0.3 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain TnsD PF15978.5 EMT54654.1 - 0.32 9.9 5.1 2.3 7.1 0.1 2.7 1 1 2 3 3 3 0 Tn7-like transposition protein D DUF4179 PF13786.6 EMT54655.1 - 1.6e-06 28.5 0.0 3.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) DUF5643 PF18705.1 EMT54655.1 - 7.6e-06 25.9 0.0 1.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5643) DUF1642 PF07852.11 EMT54655.1 - 0.079 13.5 0.3 0.32 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1642) FAD_oxidored PF12831.7 EMT54656.1 - 1.2e-111 374.1 0.0 1.4e-111 374.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMT54656.1 - 1.8e-08 33.9 2.0 4.9e-07 29.2 2.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EMT54656.1 - 9.9e-07 28.9 0.1 6.6e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMT54656.1 - 4.7e-06 26.0 0.0 7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMT54656.1 - 5.1e-06 25.8 0.6 7.8e-06 25.2 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EMT54656.1 - 0.00064 20.2 0.7 0.0077 16.8 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT54656.1 - 0.0012 17.6 1.2 0.0019 17.0 1.2 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EMT54656.1 - 0.0017 18.0 3.0 0.0037 16.9 2.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMT54656.1 - 0.026 13.8 0.6 0.046 13.0 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EMT54656.1 - 0.029 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMT54656.1 - 0.05 12.9 0.7 0.12 11.6 0.7 1.7 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EMT54656.1 - 0.092 12.0 0.1 0.092 12.0 0.1 1.5 2 0 0 2 2 2 0 Thi4 family F5_F8_type_C PF00754.25 EMT54657.1 - 0.056 13.6 0.0 0.061 13.4 0.0 1.1 1 0 0 1 1 1 0 F5/8 type C domain DinB_2 PF12867.7 EMT54658.1 - 3.5e-13 50.2 0.3 4.2e-13 49.9 0.3 1.1 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 EMT54658.1 - 6.7e-06 26.1 0.4 1e-05 25.6 0.4 1.3 1 0 0 1 1 1 1 DinB family DUF1569 PF07606.11 EMT54658.1 - 0.081 12.9 0.5 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1569) DUF4241 PF14025.6 EMT54659.1 - 5.7e-50 170.2 0.0 6.6e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4241) YCII PF03795.14 EMT54661.1 - 5.1e-10 39.6 0.0 5.4e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain NUDIX PF00293.28 EMT54662.1 - 5.8e-21 74.9 0.1 6.7e-21 74.7 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EMT54662.1 - 3e-17 62.6 0.0 3.7e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 EMT54662.1 - 0.025 14.1 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Nucleotide hydrolase UDPG_MGDP_dh_C PF03720.15 EMT54662.1 - 0.1 13.1 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Glt_symporter PF03616.14 EMT54663.1 - 1.8e-133 444.8 33.7 2.1e-133 444.6 33.7 1.0 1 0 0 1 1 1 1 Sodium/glutamate symporter Arginase PF00491.21 EMT54664.1 - 1.9e-63 214.6 0.0 2.2e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family CRISPR_Cas2 PF09827.9 EMT54664.1 - 0.035 14.3 0.1 0.089 13.0 0.1 1.6 1 0 0 1 1 1 0 CRISPR associated protein Cas2 CSTF2_hinge PF14327.6 EMT54664.1 - 0.057 13.9 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 LysR_substrate PF03466.20 EMT54665.1 - 4.1e-42 143.9 0.0 5.2e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EMT54665.1 - 9.1e-22 76.8 0.0 1.7e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_23 PF13384.6 EMT54665.1 - 0.049 13.5 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_37 PF13744.6 EMT54665.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 EMT54665.1 - 0.051 13.4 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DMPK_coil PF08826.10 EMT54665.1 - 0.062 13.4 0.7 0.18 11.9 0.3 2.0 2 0 0 2 2 2 0 DMPK coiled coil domain like HTH_24 PF13412.6 EMT54665.1 - 0.074 12.6 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 EMT54665.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 MarR family GRDP-like PF07173.12 EMT54665.1 - 0.12 13.1 0.1 0.78 10.4 0.1 2.2 2 0 0 2 2 2 0 Glycine-rich domain-containing protein-like Mga PF05043.13 EMT54665.1 - 0.18 12.4 1.8 0.4 11.3 0.1 2.4 2 1 0 2 2 2 0 Mga helix-turn-helix domain Sec8_exocyst PF04048.14 EMT54665.1 - 0.24 11.3 1.7 0.46 10.4 1.7 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Flavin_Reduct PF01613.18 EMT54666.1 - 1.4e-11 44.6 0.0 1.9e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 EMT54666.1 - 0.0063 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 EMT54666.1 - 0.15 12.2 0.0 0.55 10.5 0.0 1.8 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Mqo PF06039.15 EMT54667.1 - 6.5e-240 796.7 0.0 7.5e-240 796.5 0.0 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 EMT54667.1 - 2.6e-08 33.9 0.0 3.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMT54667.1 - 0.044 13.0 0.0 0.44 9.8 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EMT54667.1 - 0.068 11.9 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 EMT54667.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 EMT54667.1 - 0.081 12.0 0.0 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMT54667.1 - 0.1 11.8 0.0 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMT54667.1 - 0.16 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Acetyltransf_1 PF00583.25 EMT54668.1 - 4.6e-16 59.1 0.0 5.6e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EMT54668.1 - 1.7e-12 48.2 0.0 2.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMT54668.1 - 1.4e-10 41.2 0.0 1.7e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMT54668.1 - 1e-09 38.7 0.0 1.5e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT54668.1 - 4.6e-09 36.1 0.0 6.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EMT54668.1 - 2.5e-05 24.0 0.0 4.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT54668.1 - 0.00086 19.5 0.0 0.0011 19.1 0.0 1.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT54668.1 - 0.0026 17.9 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EMT54668.1 - 0.028 13.9 0.1 0.045 13.2 0.1 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase DUF1541 PF07563.11 EMT54668.1 - 0.036 13.9 0.5 0.063 13.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Sigma70_r2 PF04542.14 EMT54670.1 - 1.5e-15 56.7 0.0 3e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT54670.1 - 5.4e-10 38.8 0.4 5.4e-10 38.8 0.4 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 SnoaL_2 PF12680.7 EMT54670.1 - 0.0016 19.1 0.0 0.0028 18.3 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain Sigma70_r4 PF04545.16 EMT54670.1 - 0.002 17.6 1.4 0.0024 17.4 0.3 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Amino_oxidase PF01593.24 EMT54671.1 - 2.4e-20 73.3 0.0 7.7e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 EMT54671.1 - 3.8e-15 56.3 1.0 1.5e-14 54.4 1.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMT54671.1 - 5e-13 49.1 0.3 9.2e-13 48.2 0.3 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMT54671.1 - 2e-07 30.6 2.5 0.0027 17.0 0.4 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMT54671.1 - 2.2e-07 29.9 1.1 0.00017 20.4 0.5 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EMT54671.1 - 5.8e-07 28.9 2.4 6e-07 28.9 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EMT54671.1 - 3.5e-06 26.4 1.4 0.002 17.3 0.9 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 EMT54671.1 - 8e-06 26.3 0.3 0.017 15.7 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMT54671.1 - 1.2e-05 24.9 2.3 2.5e-05 23.8 1.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMT54671.1 - 3.4e-05 23.2 1.3 6.4e-05 22.3 1.3 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EMT54671.1 - 0.00017 21.0 0.5 0.0003 20.2 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMT54671.1 - 0.00017 20.9 0.3 0.12 11.6 0.3 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMT54671.1 - 0.00038 19.4 0.8 0.08 11.8 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 EMT54671.1 - 0.01 14.9 1.1 0.5 9.4 0.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EMT54671.1 - 0.016 15.2 0.6 5.3 7.0 0.2 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding Glug PF07581.12 EMT54672.1 - 0.17 12.4 0.1 0.17 12.4 0.1 2.3 3 0 0 3 3 3 0 The GLUG motif DUF3995 PF13160.6 EMT54673.1 - 1.9e-05 25.0 6.8 1.9e-05 25.0 6.8 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3995) DUF417 PF04224.12 EMT54673.1 - 0.067 12.7 1.2 0.16 11.5 0.4 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF417 DUF2569 PF10754.9 EMT54674.1 - 0.00028 21.3 2.3 0.00032 21.2 1.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2569) DUF2304 PF10066.9 EMT54674.1 - 0.0037 17.5 1.8 0.0037 17.5 1.8 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2304) COPI_assoc PF08507.10 EMT54674.1 - 0.02 15.0 7.1 1.1 9.4 0.3 2.3 1 1 1 2 2 2 0 COPI associated protein HupE_UreJ PF04955.12 EMT54674.1 - 0.03 13.8 5.0 0.039 13.4 5.0 1.2 1 0 0 1 1 1 0 HupE / UreJ protein DUF373 PF04123.13 EMT54674.1 - 0.031 13.7 0.3 0.038 13.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Ferric_reduct PF01794.19 EMT54674.1 - 0.1 12.7 7.3 0.36 11.0 7.3 1.8 1 1 0 1 1 1 0 Ferric reductase like transmembrane component ABC2_membrane_3 PF12698.7 EMT54674.1 - 0.13 11.3 5.4 0.15 11.1 5.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein MFS_MOT1 PF16983.5 EMT54674.1 - 0.19 12.1 4.7 0.62 10.5 4.2 2.0 1 1 0 1 1 1 0 Molybdate transporter of MFS superfamily ArsA_ATPase PF02374.15 EMT54676.1 - 9e-94 314.1 0.0 1.1e-93 313.8 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase ArsA_HSP20 PF17886.1 EMT54676.1 - 6.3e-20 70.5 0.0 1.7e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 HSP20-like domain found in ArsA AAA_31 PF13614.6 EMT54676.1 - 1.7e-09 37.9 0.0 4.2e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EMT54676.1 - 1.1e-08 35.2 2.4 5.5e-07 29.7 2.3 2.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EMT54676.1 - 7e-07 28.9 1.6 1.6e-06 27.7 0.8 2.0 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase PhoH PF02562.16 EMT54676.1 - 0.00052 19.5 0.2 0.00099 18.6 0.2 1.4 1 0 0 1 1 1 1 PhoH-like protein Fer4_NifH PF00142.18 EMT54676.1 - 0.0017 17.8 0.2 0.0039 16.7 0.2 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 EMT54676.1 - 0.0018 17.9 2.3 0.054 13.1 0.4 2.6 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EMT54676.1 - 0.0028 17.4 0.0 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EMT54676.1 - 0.0043 16.7 0.9 0.055 13.1 1.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EMT54676.1 - 0.0081 15.7 0.6 0.029 13.9 0.2 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ CobA_CobO_BtuR PF02572.15 EMT54676.1 - 0.015 15.6 1.7 0.61 10.3 1.4 2.4 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP IstB_IS21 PF01695.17 EMT54676.1 - 0.035 13.9 0.4 0.082 12.6 0.2 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein APS_kinase PF01583.20 EMT54676.1 - 0.041 13.8 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.10 EMT54676.1 - 0.13 11.7 0.1 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 EMT54676.1 - 0.19 11.4 1.5 0.31 10.7 1.5 1.5 1 1 0 1 1 1 0 AAA domain MarR PF01047.22 EMT54677.1 - 9.1e-12 44.7 0.1 1.5e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EMT54677.1 - 4.9e-10 39.2 0.3 1.9e-09 37.3 0.2 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 EMT54677.1 - 2.3e-07 31.2 0.1 3.2e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EMT54677.1 - 9.3e-05 21.9 0.1 0.00016 21.2 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EMT54677.1 - 0.00027 20.8 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 EMT54677.1 - 0.0011 18.9 0.4 0.0045 16.9 0.4 2.1 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 EMT54677.1 - 0.0017 18.5 0.1 0.003 17.7 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 EMT54677.1 - 0.0017 18.1 0.3 0.0031 17.3 0.3 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain Rrf2 PF02082.20 EMT54677.1 - 0.01 16.2 0.2 0.43 10.9 0.1 2.3 2 0 0 2 2 2 1 Transcriptional regulator DED PF01335.21 EMT54677.1 - 0.012 15.9 0.8 0.55 10.6 0.1 2.2 2 0 0 2 2 2 0 Death effector domain HTH_20 PF12840.7 EMT54677.1 - 0.13 12.3 1.4 3.4 7.8 0.3 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain rve PF00665.26 EMT54678.1 - 1.5e-12 47.8 0.0 9.7e-12 45.1 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain HTH_7 PF02796.15 EMT54678.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 EMT54678.1 - 0.15 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 EMT54678.1 - 0.21 11.4 1.2 1.2 9.0 0.0 2.6 2 1 0 2 2 2 0 Homeodomain-like domain UBA_4 PF14555.6 EMT54678.1 - 0.29 11.0 0.7 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 UBA-like domain HTH_Tnp_ISL3 PF13542.6 EMT54678.1 - 0.35 10.3 2.5 5.3 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 rve PF00665.26 EMT54679.1 - 2.3e-27 95.5 0.0 5.9e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_38 PF13936.6 EMT54679.1 - 1.4e-05 24.7 0.1 3.1e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EMT54679.1 - 4.7e-05 23.0 0.0 0.00025 20.7 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EMT54679.1 - 7.1e-05 22.9 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 EMT54679.1 - 0.00016 21.7 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 EMT54679.1 - 0.0014 18.2 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Terminase_5 PF06056.12 EMT54679.1 - 0.0038 17.1 0.0 0.0092 15.9 0.0 1.6 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_Tc3_1 PF11427.8 EMT54679.1 - 0.016 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Tc3 transposase HTH_7 PF02796.15 EMT54679.1 - 0.04 14.0 0.1 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_36 PF13730.6 EMT54679.1 - 0.04 13.9 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_40 PF14493.6 EMT54679.1 - 0.057 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 EMT54679.1 - 0.081 13.0 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_Tnp_1_2 PF13022.6 EMT54679.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase IstB_IS21 PF01695.17 EMT54680.1 - 2.1e-67 226.3 0.0 2.7e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 EMT54680.1 - 8.4e-10 38.9 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein AAA PF00004.29 EMT54680.1 - 8.9e-08 32.6 0.0 4e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMT54680.1 - 2.3e-05 24.4 0.0 3.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 EMT54680.1 - 2.8e-05 23.7 0.0 3.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.6 EMT54680.1 - 0.00022 21.7 0.2 0.00089 19.7 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMT54680.1 - 0.00024 21.4 0.1 0.029 14.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EMT54680.1 - 0.00094 18.7 0.0 0.0024 17.4 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region NTPase_1 PF03266.15 EMT54680.1 - 0.0011 18.9 0.1 0.12 12.3 0.0 2.2 1 1 1 2 2 2 1 NTPase AAA_14 PF13173.6 EMT54680.1 - 0.0012 18.9 0.5 0.0054 16.8 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 EMT54680.1 - 0.0015 18.2 0.0 0.032 13.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EMT54680.1 - 0.002 17.9 0.2 0.0051 16.6 0.2 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EMT54680.1 - 0.0035 17.1 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EMT54680.1 - 0.0093 15.2 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 EMT54680.1 - 0.019 15.4 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EMT54680.1 - 0.02 14.9 0.0 0.059 13.4 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 EMT54680.1 - 0.023 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EMT54680.1 - 0.044 13.6 0.1 0.4 10.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMT54680.1 - 0.056 14.0 0.1 0.15 12.6 0.0 1.9 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.6 EMT54680.1 - 0.056 13.6 0.0 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMT54680.1 - 0.061 13.7 0.0 0.19 12.1 0.0 1.8 2 1 0 2 2 1 0 RNA helicase AAA_19 PF13245.6 EMT54680.1 - 0.077 13.3 0.3 4.5 7.6 0.0 2.3 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.10 EMT54680.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 EMT54680.1 - 0.16 12.4 0.1 2.6 8.6 0.0 2.4 1 1 1 2 2 2 0 ABC transporter IstB_IS21 PF01695.17 EMT54682.1 - 1e-30 106.8 0.1 1.1e-30 106.7 0.1 1.0 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 EMT54682.1 - 0.0041 17.0 0.0 0.0047 16.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial dnaA protein DUF3883 PF13020.6 EMT54683.1 - 2e-11 43.8 0.0 3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) DUF4763 PF15960.5 EMT54683.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) SNF2_N PF00176.23 EMT54684.1 - 1.4e-13 50.3 0.0 1.6e-11 43.6 0.0 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EMT54684.1 - 1.9e-05 25.0 0.0 4.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMT54684.1 - 0.0022 18.0 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Radical_SAM PF04055.21 EMT54684.1 - 0.17 12.3 0.0 0.64 10.4 0.0 2.0 1 1 0 1 1 1 0 Radical SAM superfamily ddrB-ParB PF18763.1 EMT54685.1 - 0.001 19.2 0.0 0.0052 16.9 0.0 2.1 1 1 1 2 2 2 1 ddrB-like ParB superfamily domain ATP_bind_1 PF03029.17 EMT54685.1 - 0.081 12.7 0.7 0.28 10.9 0.0 2.1 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Cyclin_C PF02984.19 EMT54685.1 - 0.11 12.5 0.1 0.36 10.9 0.1 1.9 1 1 0 1 1 1 0 Cyclin, C-terminal domain HTH_36 PF13730.6 EMT54685.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain PAS_10 PF13596.6 EMT54685.1 - 0.32 11.6 2.3 0.6 10.7 0.3 2.5 2 0 0 2 2 2 0 PAS domain Lipoprotein_X PF03305.13 EMT54685.1 - 0.66 9.7 4.5 0.29 10.9 0.2 2.1 2 0 0 2 2 2 0 Mycoplasma MG185/MG260 protein Ead_Ea22 PF13935.6 EMT54685.1 - 1.8 9.2 9.5 18 6.0 9.5 2.4 1 1 0 1 1 1 0 Ead/Ea22-like protein NPV_P10 PF05531.12 EMT54685.1 - 3.6 8.1 5.5 3.2 8.3 0.0 3.4 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Endonuc-BglII PF09195.11 EMT54686.1 - 1.7e-15 57.2 0.0 2.4e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease BglII BamHI PF02923.15 EMT54686.1 - 0.09 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BamHI N6_N4_Mtase PF01555.18 EMT54687.1 - 2.6e-48 164.7 0.5 3.7e-48 164.2 0.5 1.1 1 0 0 1 1 1 1 DNA methylase Methyltransf_15 PF09445.10 EMT54687.1 - 0.00018 21.1 0.0 0.014 14.9 0.0 2.2 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EMT54687.1 - 0.16 11.6 0.0 2.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 HTH_23 PF13384.6 EMT54688.1 - 0.014 15.2 0.2 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Phage_antitermQ PF06530.12 EMT54688.1 - 0.023 14.6 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Phage antitermination protein Q GntR PF00392.21 EMT54688.1 - 0.047 13.3 0.1 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family rve PF00665.26 EMT54689.1 - 4.8e-07 30.0 0.0 6.4e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain IstB_IS21 PF01695.17 EMT54691.1 - 3.6e-26 92.0 0.0 4.8e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 EMT54691.1 - 4.9e-05 22.9 0.0 9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.6 EMT54691.1 - 0.0057 17.1 0.1 0.075 13.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.18 EMT54691.1 - 0.0083 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_7 PF12775.7 EMT54691.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Kinase-PPPase PF03618.14 EMT54691.1 - 0.034 13.9 0.0 0.056 13.2 0.0 1.6 1 1 0 1 1 1 0 Kinase/pyrophosphorylase AAA_28 PF13521.6 EMT54691.1 - 0.073 13.3 0.3 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EMT54691.1 - 0.099 12.9 0.1 0.22 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain PEPCK_ATP PF01293.20 EMT54691.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 EMT54691.1 - 0.12 12.5 0.1 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EMT54691.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 EMT54691.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EMT54691.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 EMT54692.1 - 1.1e-09 38.2 0.4 1.3e-09 38.1 0.4 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein BCD PF15461.6 EMT54694.1 - 0.0015 18.1 0.2 0.0016 18.0 0.2 1.1 1 0 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase RUN PF02759.19 EMT54695.1 - 0.042 13.8 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 RUN domain YolD PF08863.10 EMT54696.1 - 8.6e-10 38.5 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 YolD-like protein Amidase_3 PF01520.18 EMT54698.1 - 7.1e-45 153.3 0.0 9.4e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Holin_BhlA PF10960.8 EMT54699.1 - 9.3e-14 51.2 0.2 1.5e-13 50.5 0.2 1.3 1 1 0 1 1 1 1 BhlA holin family ThiF PF00899.21 EMT54699.1 - 0.016 14.6 0.0 0.018 14.4 0.0 1.0 1 0 0 1 1 1 0 ThiF family DUF2856 PF11043.8 EMT54699.1 - 0.064 13.4 0.2 0.1 12.7 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2856) BAR PF03114.18 EMT54701.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 BAR domain YopE_N PF09020.10 EMT54703.1 - 0.06 13.6 0.1 0.14 12.4 0.1 1.6 1 1 0 1 1 1 0 YopE, N terminal DUF2313 PF10076.9 EMT54704.1 - 7.3e-28 97.5 0.1 2.8e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein conserved in bacteria (DUF2313) Baseplate_J PF04865.14 EMT54705.1 - 2e-74 250.0 12.6 3.7e-74 249.1 12.6 1.4 1 0 0 1 1 1 1 Baseplate J-like protein TOBE PF03459.17 EMT54705.1 - 0.067 13.5 1.2 0.18 12.1 1.2 1.9 1 0 0 1 1 1 0 TOBE domain DUF2634 PF10934.8 EMT54706.1 - 6.9e-26 90.4 0.0 8.2e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2634) EKR PF10371.9 EMT54706.1 - 0.024 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF2577 PF10844.8 EMT54707.1 - 3.7e-18 65.6 0.0 4.3e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2577) PCB_OB PF17092.5 EMT54707.1 - 0.12 13.1 0.0 16 6.3 0.0 2.1 1 1 1 2 2 2 0 Penicillin-binding protein OB-like domain DUF5333 PF17267.2 EMT54708.1 - 0.059 13.6 0.1 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5333) Phage-tail_2 PF09096.10 EMT54708.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Baseplate structural protein, domain 2 LysM PF01476.20 EMT54709.1 - 1e-09 38.3 0.0 3.1e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 LysM domain DUF3862 PF12978.7 EMT54710.1 - 0.00094 19.0 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3862) PhageMin_Tail PF10145.9 EMT54711.1 - 1.4e-48 165.4 22.7 1.4e-48 165.4 22.7 3.5 3 1 2 5 5 5 1 Phage-related minor tail protein Phage_TAC_5 PF08890.11 EMT54712.1 - 3e-24 85.6 0.0 3.3e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Phage XkdN-like tail assembly chaperone protein, TAC DUF2001 PF09393.10 EMT54713.1 - 5e-41 139.9 0.1 5.5e-41 139.8 0.1 1.0 1 0 0 1 1 1 1 Phage tail tube protein YfkD PF14167.6 EMT54713.1 - 0.014 14.6 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 YfkD-like protein DUF4934 PF16288.5 EMT54713.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) Phage_sheath_1 PF04984.14 EMT54714.1 - 1.3e-14 54.4 0.3 2.1e-14 53.7 0.3 1.4 1 0 0 1 1 1 1 Phage tail sheath protein subtilisin-like domain Phage_sheath_1C PF17482.2 EMT54714.1 - 5.4e-13 48.8 0.0 1.4e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Phage tail sheath C-terminal domain Prok_Ub PF14454.6 EMT54714.1 - 0.023 14.3 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic Ubiquitin PTR PF12789.7 EMT54720.1 - 1.9e-05 24.6 1.2 4.2e-05 23.5 1.2 1.7 1 0 0 1 1 1 1 Phage tail repeat like Phage_head_fibr PF11133.8 EMT54720.1 - 2.6e-05 23.8 8.5 2.6e-05 23.8 8.5 2.1 1 1 1 2 2 2 1 Head fiber protein FSA_C PF10479.9 EMT54720.1 - 0.89 7.6 8.2 1 7.4 8.2 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF5309 PF17236.2 EMT54721.1 - 5.9e-32 111.1 1.9 9.6e-30 103.9 0.6 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5309) DUF4355 PF14265.6 EMT54722.1 - 0.0012 19.1 25.4 0.0012 19.1 25.4 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4355) FAM110_N PF14161.6 EMT54722.1 - 0.052 13.8 1.9 0.12 12.6 1.9 1.6 1 0 0 1 1 1 0 Centrosome-associated N terminus eIF3_N PF09440.10 EMT54722.1 - 0.76 10.2 10.4 0.13 12.7 6.5 1.7 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain HHH_6 PF14579.6 EMT54722.1 - 0.97 9.7 6.5 0.35 11.1 1.4 2.6 2 1 1 3 3 3 0 Helix-hairpin-helix motif DivIVA PF05103.13 EMT54722.1 - 1.6 8.8 20.3 7.7 6.6 17.2 2.2 2 0 0 2 2 2 0 DivIVA protein ARGLU PF15346.6 EMT54722.1 - 2.1 8.2 26.0 0.35 10.7 21.9 1.7 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Phage_min_cap2 PF06152.11 EMT54723.1 - 3.1e-18 65.8 0.3 4.1e-18 65.4 0.3 1.1 1 0 0 1 1 1 1 Phage minor capsid protein 2 ACCA PF03255.14 EMT54723.1 - 0.18 11.7 1.9 0.58 10.0 0.1 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Phage_prot_Gp6 PF05133.14 EMT54724.1 - 7.2e-12 45.1 0.0 1.1e-10 41.2 0.0 2.0 1 1 0 1 1 1 1 Phage portal protein, SPP1 Gp6-like HTH_Tnp_1_2 PF13022.6 EMT54726.1 - 6.8e-21 74.7 0.0 8.8e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 EMT54726.1 - 0.00049 19.8 0.4 0.0049 16.6 0.1 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EMT54726.1 - 0.0021 18.1 0.4 0.011 15.9 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_17 PF12728.7 EMT54726.1 - 0.0022 18.1 0.0 0.033 14.4 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain SPOB_ab PF14682.6 EMT54726.1 - 0.0051 16.9 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 Sporulation initiation phospho-transferase B, C-terminal TetR_N PF00440.23 EMT54726.1 - 0.012 15.4 0.6 0.021 14.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_3 PF01381.22 EMT54726.1 - 0.014 15.4 1.5 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix HTH_Tnp_1 PF01527.20 EMT54726.1 - 0.027 14.8 0.2 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_Mga PF08280.11 EMT54726.1 - 0.031 14.3 0.0 0.093 12.8 0.0 1.7 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_AraC PF00165.23 EMT54726.1 - 0.046 13.8 0.0 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_29 PF13551.6 EMT54726.1 - 0.065 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix HTH_11 PF08279.12 EMT54726.1 - 0.12 12.3 0.0 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 HTH domain HTH_31 PF13560.6 EMT54726.1 - 0.58 10.5 4.6 0.45 10.9 0.8 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EMT54728.1 - 1.2e-07 31.6 0.0 0.026 14.5 0.0 2.6 2 0 0 2 2 2 2 Crp-like helix-turn-helix domain HTH_24 PF13412.6 EMT54728.1 - 8.5e-06 25.2 0.3 0.003 17.1 0.0 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EMT54728.1 - 1.4e-05 24.8 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EMT54728.1 - 2.5e-05 24.5 0.0 0.034 14.5 0.0 2.3 2 0 0 2 2 2 2 Transcriptional regulator Replic_Relax PF13814.6 EMT54728.1 - 0.00017 21.7 0.0 0.036 14.1 0.0 2.5 3 0 0 3 3 3 1 Replication-relaxation GntR PF00392.21 EMT54728.1 - 0.00019 21.0 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, gntR family Phage_rep_O PF04492.13 EMT54728.1 - 0.0014 19.2 0.0 0.74 10.4 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage replication protein O SMC_ScpB PF04079.16 EMT54728.1 - 0.0028 17.3 0.0 0.072 12.7 0.0 2.5 3 0 0 3 3 3 1 Segregation and condensation complex subunit ScpB HTH_11 PF08279.12 EMT54728.1 - 0.0035 17.2 0.0 0.0093 15.9 0.0 1.7 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 EMT54728.1 - 0.0042 17.0 0.0 0.33 10.9 0.0 2.6 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 EMT54728.1 - 0.0063 17.0 0.1 7.6 7.1 0.0 2.9 3 0 0 3 3 3 1 Winged helix DNA-binding domain HTH_5 PF01022.20 EMT54728.1 - 0.012 15.5 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_36 PF13730.6 EMT54728.1 - 0.029 14.3 0.0 0.41 10.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 EMT54728.1 - 0.063 13.5 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 EMT54728.1 - 0.071 13.1 0.1 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 MarR family HTH_Tnp_4 PF13613.6 EMT54728.1 - 0.085 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease SAP18 PF06487.12 EMT54733.1 - 0.071 13.3 0.0 0.082 13.1 0.0 1.1 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) HTH_26 PF13443.6 EMT54734.1 - 3.1e-11 43.5 0.0 3.4e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain DUF3562 PF12085.8 EMT54734.1 - 4e-05 23.1 0.2 4.9e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3562) HTH_19 PF12844.7 EMT54734.1 - 9.4e-05 22.4 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EMT54734.1 - 0.00067 19.9 0.0 0.0009 19.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EMT54734.1 - 0.015 15.3 0.1 0.094 12.8 0.1 1.9 1 1 0 1 1 1 0 Helix-turn-helix HTH_38 PF13936.6 EMT54734.1 - 0.058 13.2 0.1 0.086 12.6 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_15 PF12324.8 EMT54734.1 - 0.1 12.6 0.0 0.32 11.0 0.0 1.7 1 1 1 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase TniQ PF06527.11 EMT54734.1 - 0.18 12.5 0.0 0.21 12.3 0.0 1.0 1 0 0 1 1 1 0 TniQ DUF1561 PF07598.11 EMT54735.1 - 0.047 11.9 0.0 0.047 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) Sigma70_r4 PF04545.16 EMT54738.1 - 6.2e-11 41.6 0.1 1.1e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 UPF0122 PF04297.14 EMT54738.1 - 4.8e-05 23.5 0.0 7.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like DUF134 PF02001.16 EMT54738.1 - 9.7e-05 22.9 0.3 0.00034 21.1 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function DUF134 Sigma70_r4_2 PF08281.12 EMT54738.1 - 0.00076 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT54738.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 ECF sigma factor KORA PF16509.5 EMT54738.1 - 0.028 14.7 0.3 0.047 14.0 0.3 1.4 1 1 0 1 1 1 0 TrfB plasmid transcriptional repressor MarR_2 PF12802.7 EMT54738.1 - 0.038 13.9 0.1 0.071 13.0 0.1 1.5 1 0 0 1 1 1 0 MarR family GSH_synthase PF03199.15 EMT54738.1 - 0.079 13.4 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic glutathione synthase HTH_3 PF01381.22 EMT54738.1 - 0.084 12.9 0.0 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix DUF5622 PF18533.1 EMT54739.1 - 0.018 15.2 0.1 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5622) AAA_18 PF13238.6 EMT54741.1 - 5.6e-05 23.7 0.0 0.00027 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EMT54741.1 - 0.01 16.3 0.0 0.041 14.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain HNH_3 PF13392.6 EMT54742.1 - 3e-13 49.3 0.1 5.2e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease MerR_1 PF13411.6 EMT54742.1 - 0.0088 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 MerR HTH family regulatory protein UPF0175 PF03683.13 EMT54742.1 - 0.027 14.2 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) ARGLU PF15346.6 EMT54743.1 - 0.0035 17.2 0.3 0.0071 16.2 0.3 1.4 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 SH3_12 PF18129.1 EMT54743.1 - 0.014 15.5 0.0 0.041 14.0 0.0 1.8 1 0 0 1 1 1 0 Xrn1 SH3-like domain DUF1876 PF08962.11 EMT54743.1 - 0.028 14.4 0.2 0.13 12.2 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1876) 3D PF06725.11 EMT54744.1 - 1.7e-05 24.9 0.0 2.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 3D domain Thy1 PF02511.15 EMT54745.1 - 8e-53 179.0 0.0 9.9e-53 178.7 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase complementing protein dUTPase_2 PF08761.11 EMT54746.1 - 1.3e-20 74.3 2.3 9.3e-16 58.4 0.4 2.0 1 1 1 2 2 2 2 dUTPase DUF308 PF03729.13 EMT54747.1 - 0.00022 21.5 4.1 0.00031 21.0 4.1 1.2 1 0 0 1 1 1 1 Short repeat of unknown function (DUF308) Phage_holin_3_6 PF07332.11 EMT54747.1 - 0.0038 17.3 1.9 0.0045 17.0 1.9 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4064 PF13273.6 EMT54747.1 - 0.057 13.7 4.1 0.11 12.8 4.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) RNR_Alpha PF17975.1 EMT54748.1 - 1.8e-30 105.4 0.3 1.2e-28 99.6 0.1 2.9 3 0 0 3 3 3 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 EMT54748.1 - 5.2e-07 28.6 0.0 6.5e-05 21.7 0.0 3.1 3 0 0 3 3 3 2 Ribonucleotide reductase, barrel domain LemA PF04011.12 EMT54749.1 - 0.031 14.1 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 LemA family Methyltransf_11 PF08241.12 EMT54749.1 - 0.073 13.7 0.0 0.083 13.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain DUF4229 PF14012.6 EMT54750.1 - 2.5 8.3 11.3 19 5.4 11.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4229) FA_desaturase PF00487.24 EMT54750.1 - 3.4 7.4 7.9 3.6 7.4 7.9 1.1 1 0 0 1 1 1 0 Fatty acid desaturase RuvC PF02075.17 EMT54751.1 - 2.9e-07 30.5 0.0 4.2e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC RNase_T PF00929.24 EMT54752.1 - 1.3e-23 84.3 0.1 3.6e-23 82.9 0.1 1.6 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EMT54752.1 - 4.2e-07 29.8 0.0 0.00011 22.0 0.0 2.9 2 1 0 2 2 2 2 3'-5' exonuclease DUF5051 PF16473.5 EMT54752.1 - 5.1e-06 26.6 0.0 2e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DUF848 PF05852.11 EMT54753.1 - 0.014 15.5 0.2 0.018 15.2 0.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) WXG100 PF06013.12 EMT54753.1 - 0.043 14.0 0.1 2.3 8.5 0.2 2.3 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF2555 PF10742.9 EMT54753.1 - 0.064 13.1 0.2 0.16 11.9 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2555) DNA_pol_A PF00476.20 EMT54755.1 - 4.5e-98 328.7 0.0 6.5e-98 328.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EMT54755.1 - 1.8e-18 66.9 0.4 3.6e-18 65.9 0.0 1.7 2 0 0 2 2 2 1 3'-5' exonuclease His_biosynth PF00977.21 EMT54755.1 - 0.03 13.8 0.0 0.077 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF2196 PF09962.9 EMT54756.1 - 0.03 14.3 6.5 0.6 10.1 0.1 4.1 4 2 0 4 4 4 0 Uncharacterized conserved protein (DUF2196) GTP_EFTU_D2 PF03144.25 EMT54756.1 - 0.094 13.1 9.4 10 6.6 0.4 4.1 4 0 0 4 4 4 0 Elongation factor Tu domain 2 HAS-barrel PF09378.10 EMT54756.1 - 0.1 12.8 0.4 0.1 12.8 0.4 3.0 3 1 0 3 3 3 0 HAS barrel domain SH3_2 PF07653.17 EMT54756.1 - 0.1 12.3 8.0 6.8 6.5 0.1 4.6 5 0 0 5 5 5 0 Variant SH3 domain PUA PF01472.20 EMT54756.1 - 0.57 10.2 3.3 5.8 7.0 0.2 3.6 3 1 1 4 4 4 0 PUA domain PDDEXK_5 PF11645.8 EMT54757.1 - 1.8e-06 28.0 0.0 2.3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 PD-(D/E)XK endonuclease DUF1771 PF08590.10 EMT54759.1 - 4.7 7.7 9.9 0.079 13.4 2.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) DASH_Spc19 PF08287.11 EMT54761.1 - 0.0014 18.5 0.7 0.0025 17.7 0.7 1.3 1 0 0 1 1 1 1 Spc19 Osmo_CC PF08946.10 EMT54761.1 - 0.095 13.0 0.3 0.095 13.0 0.3 2.0 2 0 0 2 2 2 0 Osmosensory transporter coiled coil NBP1 PF08537.10 EMT54761.1 - 0.097 12.1 1.5 0.31 10.4 0.1 2.0 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 Siah-Interact_N PF09032.11 EMT54761.1 - 0.43 10.9 3.5 0.43 10.9 0.5 2.3 1 1 1 2 2 2 0 Siah interacting protein, N terminal HTH_Tnp_ISL3 PF13542.6 EMT54762.1 - 0.00025 20.4 0.1 0.06 12.8 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 EMT54762.1 - 0.00058 19.7 0.1 0.0024 17.7 0.1 2.0 1 1 0 1 1 1 1 MarR family HTH_1 PF00126.27 EMT54762.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family TrmB PF01978.19 EMT54762.1 - 0.016 15.0 0.1 0.06 13.2 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.6 EMT54762.1 - 0.031 14.1 0.0 0.093 12.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 EMT54762.1 - 0.036 13.9 0.2 0.065 13.1 0.2 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 EMT54762.1 - 0.038 14.2 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_28 PF13518.6 EMT54762.1 - 0.047 13.8 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 EMT54762.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EMT54762.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Sigma70_r2 PF04542.14 EMT54762.1 - 0.096 12.5 0.0 0.24 11.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-70 region 2 HTH_36 PF13730.6 EMT54762.1 - 0.097 12.6 0.1 0.37 10.8 0.1 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain Hormone_2 PF00123.20 EMT54762.1 - 0.099 12.6 0.1 6.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Peptide hormone MarR PF01047.22 EMT54762.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.20 EMT54762.1 - 0.14 12.0 0.3 0.32 10.9 0.3 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TLP1_add_C PF18313.1 EMT54762.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain Cro PF09048.10 EMT54762.1 - 0.17 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Cro TPR_2 PF07719.17 EMT54763.1 - 1.5e-09 37.3 15.4 0.00094 19.1 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EMT54763.1 - 1.6e-07 31.8 3.1 0.018 15.7 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMT54763.1 - 2.2e-07 31.1 14.4 0.067 13.5 0.8 5.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMT54763.1 - 5.7e-06 26.7 3.0 0.0084 16.6 0.0 4.3 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EMT54763.1 - 1.2e-05 25.0 11.9 0.25 11.3 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat HTH_31 PF13560.6 EMT54763.1 - 0.00026 21.3 0.0 0.0007 19.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain TPR_14 PF13428.6 EMT54763.1 - 0.00032 21.3 5.5 0.82 10.7 0.0 4.8 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMT54763.1 - 0.00088 19.1 1.9 0.055 13.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMT54763.1 - 0.0023 17.7 15.5 0.014 15.1 0.2 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EMT54763.1 - 0.12 13.0 4.9 18 6.3 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMT54763.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.8 3 0 0 3 3 3 0 TPR repeat ANAPC3 PF12895.7 EMT54763.1 - 3.3 8.0 12.1 1.5 9.1 4.6 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EMT54763.1 - 5.6 7.4 15.8 2.1 8.8 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Toprim_2 PF13155.6 EMT54764.1 - 3.2e-10 40.3 0.0 5.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 EMT54764.1 - 0.002 18.6 0.1 0.0033 17.9 0.1 1.3 1 0 0 1 1 1 1 Toprim domain DnaB_C PF03796.15 EMT54766.1 - 4.6e-07 29.4 0.0 1e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 EMT54766.1 - 1.6e-05 24.6 0.2 7.8e-05 22.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain DnaB PF00772.21 EMT54766.1 - 0.068 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain ACT_3 PF10000.9 EMT54767.1 - 0.037 13.9 0.0 5.9 6.9 0.0 2.1 2 0 0 2 2 2 0 ACT domain IstB_IS21 PF01695.17 EMT54768.1 - 1.5e-06 28.1 0.2 7.4e-05 22.6 0.0 2.4 3 0 0 3 3 3 1 IstB-like ATP binding protein ResIII PF04851.15 EMT54768.1 - 0.0016 18.5 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 EMT54768.1 - 0.021 15.2 0.1 0.094 13.1 0.1 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMT54768.1 - 0.037 14.4 0.3 0.55 10.6 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 EMT54768.1 - 0.038 13.0 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Phage_TAC_1 PF06222.11 EMT54768.1 - 0.07 12.9 0.1 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Phage tail assembly chaperone AAA_22 PF13401.6 EMT54768.1 - 0.18 12.1 1.2 0.47 10.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF373 PF04123.13 EMT54773.1 - 0.058 12.8 0.8 0.07 12.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2892 PF11127.8 EMT54773.1 - 0.3 11.1 9.7 0.6 10.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DAGK_prokar PF01219.19 EMT54773.1 - 3.3 7.6 7.0 7 6.5 1.5 2.1 1 1 1 2 2 2 0 Prokaryotic diacylglycerol kinase DUF1192 PF06698.11 EMT54775.1 - 0.02 14.9 0.3 0.047 13.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) WD40_alt PF14077.6 EMT54775.1 - 0.051 13.4 0.1 0.077 12.9 0.1 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif 7tm_3 PF00003.22 EMT54778.1 - 1.7e-05 24.7 0.6 1.8e-05 24.6 0.6 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Cyt_bd_oxida_II PF02322.15 EMT54778.1 - 0.0044 16.4 0.8 0.0048 16.3 0.8 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II DUF4131 PF13567.6 EMT54778.1 - 0.0061 16.2 1.1 0.0083 15.8 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Sdh_cyt PF01127.22 EMT54778.1 - 0.027 14.5 0.8 0.037 14.1 0.8 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PTS_IIB PF02302.17 EMT54778.1 - 0.37 11.5 1.0 4.9 7.9 0.0 2.3 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit Ead_Ea22 PF13935.6 EMT54779.1 - 0.00043 21.0 0.1 0.00052 20.7 0.1 1.2 1 0 0 1 1 1 1 Ead/Ea22-like protein DUF3945 PF13101.6 EMT54780.1 - 0.027 14.2 0.2 0.9 9.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) DUF917 PF06032.12 EMT54780.1 - 0.2 10.5 0.0 0.22 10.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF917) HTH_50 PF18024.1 EMT54783.1 - 0.07 12.8 0.7 3.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain ParBc PF02195.18 EMT54784.1 - 1.7e-08 34.6 2.1 1.8e-08 34.6 0.1 2.1 3 0 0 3 3 3 1 ParB-like nuclease domain DUF1315 PF07023.12 EMT54784.1 - 0.096 12.8 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1315) HTH_36 PF13730.6 EMT54785.1 - 6.2e-10 38.9 0.0 9.8e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 EMT54785.1 - 0.00045 20.0 0.1 0.00076 19.3 0.1 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 EMT54785.1 - 0.0023 17.8 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EMT54785.1 - 0.0024 17.4 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 EMT54785.1 - 0.0043 17.0 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_Tnp_4 PF13613.6 EMT54785.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.6 EMT54785.1 - 0.028 14.2 0.9 0.074 12.9 0.9 1.8 1 1 0 1 1 1 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 EMT54785.1 - 0.031 14.2 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_28 PF13518.6 EMT54785.1 - 0.042 14.0 0.2 0.081 13.1 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_50 PF18024.1 EMT54785.1 - 0.045 13.4 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 EMT54785.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Sigma70_r4 PF04545.16 EMT54785.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_integrase PF00589.22 EMT54787.1 - 3.8e-42 144.0 0.5 6.7e-42 143.2 0.5 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_5 PF13102.6 EMT54787.1 - 1.1e-05 25.6 0.3 3.4e-05 24.1 0.1 1.9 2 0 0 2 2 2 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 EMT54787.1 - 0.00044 20.7 0.2 0.0014 19.1 0.2 1.9 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 EMT54787.1 - 0.0083 16.4 0.1 0.083 13.2 0.1 2.5 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain PgpA PF04608.13 EMT54788.1 - 5.8e-16 58.8 0.0 7.2e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylglycerophosphatase A Esterase PF00756.20 EMT54790.1 - 2e-41 142.3 0.0 3.2e-41 141.6 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EMT54790.1 - 0.0042 16.4 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 OAD_gamma PF04277.13 EMT54791.1 - 0.004 17.7 0.2 0.0041 17.7 0.2 1.1 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain OppC_N PF12911.7 EMT54791.1 - 0.059 13.3 1.3 0.069 13.1 1.3 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Hanta_G2 PF01561.16 EMT54791.1 - 0.44 9.1 1.1 0.46 9.0 1.1 1.0 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 2_5_RNA_ligase2 PF13563.6 EMT54792.1 - 6.3e-23 81.4 0.3 7.2e-23 81.2 0.3 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EMT54792.1 - 3.8e-07 30.2 0.1 0.0032 17.6 0.0 2.6 2 1 0 2 2 2 2 LigT like Phosphoesterase Acetyltransf_10 PF13673.7 EMT54793.1 - 2.1e-24 85.9 0.4 2.5e-24 85.6 0.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMT54793.1 - 1.4e-15 57.5 0.1 1.9e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMT54793.1 - 1.4e-12 47.8 0.1 2.1e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMT54793.1 - 2e-06 27.7 0.1 3.2e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EMT54793.1 - 0.00012 22.2 0.4 0.0006 19.9 0.4 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMT54793.1 - 0.00059 20.0 0.0 0.00089 19.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EMT54793.1 - 0.0021 18.7 0.0 0.0039 17.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMT54793.1 - 0.043 14.0 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PHP PF02811.19 EMT54794.1 - 9.5e-11 42.3 0.0 1.3e-10 41.8 0.0 1.3 1 1 0 1 1 1 1 PHP domain AP_endonuc_2 PF01261.24 EMT54794.1 - 0.00074 19.0 0.2 0.14 11.6 0.0 2.5 2 1 0 2 2 2 2 Xylose isomerase-like TIM barrel PHP_C PF13263.6 EMT54794.1 - 0.0047 16.6 0.0 0.016 14.9 0.0 1.9 1 0 0 1 1 1 1 PHP-associated PRP4 PF08799.11 EMT54794.1 - 0.12 12.0 0.3 3.2 7.4 0.1 2.4 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like Lactamase_B PF00753.27 EMT54796.1 - 3.1e-20 73.0 0.0 5e-20 72.4 0.0 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMT54796.1 - 6.9e-08 32.2 0.0 2.1e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EMT54796.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain YitT_membrane PF02588.15 EMT54797.1 - 7.9e-34 116.8 13.5 9.5e-34 116.6 13.5 1.0 1 0 0 1 1 1 1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DUF21 PF01595.20 EMT54798.1 - 7.8e-51 172.3 2.1 1.2e-50 171.7 2.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 EMT54798.1 - 8.2e-18 64.2 0.1 2.7e-17 62.6 0.1 1.9 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 EMT54798.1 - 6.5e-16 58.5 3.1 4.6e-08 33.4 0.1 2.7 3 0 0 3 3 3 2 CBS domain UvrD-helicase PF00580.21 EMT54799.1 - 5.2e-65 220.0 1.3 4.5e-63 213.7 1.3 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EMT54799.1 - 1.7e-41 142.8 0.0 1.9e-20 73.6 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EMT54799.1 - 2.2e-32 112.4 0.0 1.1e-31 110.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EMT54799.1 - 1.5e-12 47.2 0.4 5.7e-12 45.3 0.4 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EMT54799.1 - 6.9e-08 32.4 1.7 3.3e-05 23.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_12 PF13087.6 EMT54799.1 - 0.0015 18.2 0.0 0.11 12.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 EMT54799.1 - 0.0053 16.5 0.1 0.38 10.5 0.0 3.1 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EMT54799.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MCPsignal PF00015.21 EMT54800.1 - 1e-23 84.0 20.9 2.7e-21 76.1 10.8 2.4 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.9 EMT54800.1 - 0.00018 21.7 7.3 0.00048 20.4 2.0 2.3 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EMT54800.1 - 0.003 17.8 8.6 0.014 15.6 0.7 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) z-alpha PF02295.17 EMT54800.1 - 0.0062 16.6 1.3 0.09 12.8 1.0 2.8 2 0 0 2 2 2 1 Adenosine deaminase z-alpha domain CortBP2 PF09727.9 EMT54800.1 - 0.01 15.8 1.0 0.01 15.8 1.0 1.8 2 0 0 2 2 2 1 Cortactin-binding protein-2 Tex_N PF09371.10 EMT54800.1 - 0.021 14.5 6.2 0.077 12.7 1.6 2.3 2 0 0 2 2 2 0 Tex-like protein N-terminal domain DUF1664 PF07889.12 EMT54800.1 - 0.024 14.7 7.7 0.71 9.9 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DegS PF05384.11 EMT54800.1 - 0.031 13.7 1.4 0.031 13.7 1.4 2.2 2 0 0 2 2 2 0 Sensor protein DegS DUF4200 PF13863.6 EMT54800.1 - 0.036 14.5 5.5 0.036 14.5 5.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_23 PF13476.6 EMT54800.1 - 0.056 13.9 0.2 0.07 13.6 0.2 1.2 1 0 0 1 1 1 0 AAA domain Dor1 PF04124.12 EMT54800.1 - 0.15 10.7 7.1 0.31 9.7 2.0 2.1 1 1 1 2 2 2 0 Dor1-like family KIP1 PF07765.12 EMT54800.1 - 0.17 12.0 3.1 7.3 6.8 1.2 2.5 2 0 0 2 2 2 0 KIP1-like protein HetR_C PF18460.1 EMT54800.1 - 0.2 11.6 0.9 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain COG2 PF06148.11 EMT54800.1 - 0.23 11.6 8.6 0.44 10.6 3.1 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4263 PF14082.6 EMT54800.1 - 0.26 11.5 1.3 8.2 6.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4263) DASH_Dad3 PF08656.10 EMT54800.1 - 0.31 11.2 4.4 5.4 7.2 1.0 3.2 1 1 1 2 2 2 0 DASH complex subunit Dad3 eIF3_N PF09440.10 EMT54800.1 - 0.44 11.0 7.1 5.8 7.4 2.1 2.3 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain MRPL52 PF18699.1 EMT54800.1 - 0.57 10.4 3.7 0.61 10.3 0.7 2.2 2 0 0 2 2 2 0 Mitoribosomal protein mL52 T7SS_ESX_EspC PF10824.8 EMT54800.1 - 0.67 10.5 9.8 0.87 10.1 3.0 2.5 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Serine_rich PF08824.10 EMT54800.1 - 1.5 8.8 7.7 4 7.4 1.1 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain Laminin_II PF06009.12 EMT54800.1 - 2.2 8.3 12.5 0.76 9.8 3.4 2.5 2 0 0 2 2 2 0 Laminin Domain II Sec34 PF04136.15 EMT54800.1 - 2.3 8.1 9.0 0.71 9.8 2.4 2.1 2 0 0 2 2 2 0 Sec34-like family CHDCT2 PF08074.11 EMT54800.1 - 3.9 7.6 8.4 0.67 10.1 1.6 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain NPV_P10 PF05531.12 EMT54800.1 - 4.5 7.8 8.5 0.91 10.0 1.2 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 EMT54800.1 - 5.6 6.1 6.8 5.9 6.0 1.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF2203 PF09969.9 EMT54800.1 - 5.9 7.6 6.3 11 6.7 1.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF812 PF05667.11 EMT54800.1 - 6 5.6 13.4 66 2.2 12.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) MFS_1 PF07690.16 EMT54801.1 - 5.7e-61 206.4 45.2 5.7e-61 206.4 45.2 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT54801.1 - 2.9e-16 59.4 36.9 5.6e-12 45.3 12.6 2.4 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EMT54801.1 - 5e-13 49.1 32.1 6.3e-13 48.7 32.1 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 EMT54801.1 - 4.3e-09 35.4 22.5 4.3e-09 35.4 22.5 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.19 EMT54801.1 - 4.6e-08 32.3 23.8 0.00043 19.2 8.0 3.1 3 0 0 3 3 3 3 LacY proton/sugar symporter MFS_1_like PF12832.7 EMT54801.1 - 6.4e-07 28.6 29.1 1.1e-05 24.5 6.2 2.8 1 1 1 2 2 2 2 MFS_1 like family ATG22 PF11700.8 EMT54801.1 - 1.4e-05 24.0 19.9 1.4e-05 24.0 19.9 2.1 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_3 PF05977.13 EMT54801.1 - 0.00011 20.8 22.2 0.00029 19.4 5.3 2.1 1 1 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.20 EMT54801.1 - 0.00054 18.4 1.5 0.00054 18.4 1.5 3.2 1 1 3 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family DUF4503 PF14951.6 EMT54801.1 - 0.048 12.1 0.0 0.082 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Nuc_H_symport PF03825.16 EMT54801.1 - 0.49 9.3 31.4 0.36 9.8 14.9 3.6 1 1 2 3 3 3 0 Nucleoside H+ symporter DUF3185 PF11381.8 EMT54801.1 - 3.7 7.6 11.6 24 5.1 1.3 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3185) DUF2614 PF11023.8 EMT54801.1 - 5.7 7.1 7.6 0.97 9.5 2.2 2.5 2 0 0 2 2 2 0 Zinc-ribbon containing domain FAD_oxidored PF12831.7 EMT54802.1 - 2.3e-92 310.6 3.7 3.9e-92 309.9 3.7 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMT54802.1 - 3.3e-07 29.8 0.3 8.1e-07 28.5 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMT54802.1 - 5.8e-07 28.9 3.7 5.8e-07 28.9 3.7 2.0 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.24 EMT54802.1 - 5.3e-06 26.3 6.7 1.2e-05 25.1 6.2 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMT54802.1 - 2.6e-05 23.1 4.1 3.7e-05 22.6 1.9 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EMT54802.1 - 8.9e-05 22.6 1.5 0.0003 21.0 1.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EMT54802.1 - 0.00011 21.4 6.2 0.00014 21.1 3.9 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EMT54802.1 - 0.00063 20.2 0.6 0.076 13.6 0.8 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMT54802.1 - 0.022 14.0 0.6 0.06 12.6 0.6 1.7 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 EMT54802.1 - 0.039 13.2 0.7 0.061 12.6 0.7 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 EMT54802.1 - 0.078 12.9 1.8 0.11 12.4 1.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EMT54802.1 - 0.13 11.5 2.1 0.22 10.8 2.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMT54802.1 - 0.16 11.0 3.0 1.4 7.8 3.0 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EMT54802.1 - 0.84 8.9 9.4 0.21 10.8 3.4 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain LysR_substrate PF03466.20 EMT54803.1 - 1.4e-47 161.8 0.4 2.1e-47 161.2 0.1 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 EMT54803.1 - 7.3e-22 77.1 0.7 1.7e-21 75.9 0.3 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 EMT54803.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 EMT54803.1 - 0.017 15.0 0.9 0.028 14.3 0.1 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_30 PF13556.6 EMT54803.1 - 0.044 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_34 PF13601.6 EMT54803.1 - 0.051 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain SBP_bac_3 PF00497.20 EMT54803.1 - 0.054 12.9 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 HTH_24 PF13412.6 EMT54803.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding adh_short_C2 PF13561.6 EMT54804.1 - 8.9e-89 297.1 1.2 1e-88 296.9 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMT54804.1 - 8.1e-23 80.9 0.9 1.1e-22 80.5 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMT54804.1 - 4.2e-06 26.8 0.2 1e-05 25.5 0.1 1.7 2 0 0 2 2 2 1 KR domain AdoHcyase_NAD PF00670.21 EMT54804.1 - 0.08 13.0 0.2 0.21 11.7 0.2 1.8 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Arm-DNA-bind_2 PF12167.8 EMT54804.1 - 0.1 12.5 0.1 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Arm DNA-binding domain Zip PF02535.22 EMT54805.1 - 3.9e-15 55.9 26.4 1.8e-13 50.4 10.2 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter MerR_1 PF13411.6 EMT54806.1 - 3.7e-05 23.7 0.6 6.9e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 MerR HTH family regulatory protein T3SS_needle_F PF09392.10 EMT54806.1 - 0.00013 22.0 1.3 0.0009 19.4 1.5 2.2 2 0 0 2 2 2 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF MerR PF00376.23 EMT54806.1 - 0.00063 19.4 0.0 0.002 17.8 0.0 1.8 2 0 0 2 2 2 1 MerR family regulatory protein HTH_23 PF13384.6 EMT54806.1 - 0.00078 19.2 0.0 0.0025 17.6 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.7 EMT54806.1 - 0.0017 18.5 0.1 0.027 14.7 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain DUF746 PF05344.11 EMT54806.1 - 0.0037 17.0 1.3 0.066 13.0 0.0 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF746) MatP_C PF17414.2 EMT54806.1 - 0.042 14.0 0.9 0.19 11.9 0.9 2.2 1 1 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain HTH_Tnp_1 PF01527.20 EMT54806.1 - 0.066 13.5 0.7 0.89 9.9 0.1 2.5 2 1 0 2 2 2 0 Transposase HTH_30 PF13556.6 EMT54806.1 - 0.21 11.4 1.3 0.7 9.7 0.0 2.4 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain Rootletin PF15035.6 EMT54806.1 - 0.29 11.1 10.9 0.49 10.4 10.9 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion HD_5 PF13487.6 EMT54807.1 - 3.2e-11 43.3 0.2 7.1e-11 42.2 0.2 1.6 1 0 0 1 1 1 1 HD domain HD PF01966.22 EMT54807.1 - 2.2e-10 40.8 0.2 4.6e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 HD domain TerC PF03741.16 EMT54808.1 - 4.4e-44 150.3 15.9 4.4e-44 150.3 15.9 1.4 2 0 0 2 2 2 1 Integral membrane protein TerC family Aminotran_1_2 PF00155.21 EMT54810.1 - 2.1e-34 119.3 0.0 2.5e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EMT54810.1 - 1.6e-19 69.3 0.1 3.6e-19 68.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 EMT54810.1 - 1.1e-13 50.8 0.0 4.7e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase HTH_Crp_2 PF13545.6 EMT54810.1 - 0.00054 19.9 1.6 0.0014 18.6 0.0 2.5 4 0 0 4 4 3 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 EMT54810.1 - 0.0011 18.9 1.1 0.0022 17.9 0.1 2.0 2 0 0 2 2 2 1 HTH domain HTH_36 PF13730.6 EMT54810.1 - 0.0017 18.3 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DegT_DnrJ_EryC1 PF01041.17 EMT54810.1 - 0.0018 17.6 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family HTH_CodY PF08222.11 EMT54810.1 - 0.0042 16.6 0.1 0.015 14.9 0.1 1.9 1 0 0 1 1 1 1 CodY helix-turn-helix domain MarR PF01047.22 EMT54810.1 - 0.024 14.6 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 EMT54810.1 - 0.027 14.8 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_50 PF18024.1 EMT54810.1 - 0.054 13.1 0.0 0.18 11.4 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Aminotran_5 PF00266.19 EMT54810.1 - 0.086 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V HTH_29 PF13551.6 EMT54810.1 - 0.093 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix AzlC PF03591.14 EMT54811.1 - 1.1e-39 135.9 9.3 1.1e-39 135.9 9.3 1.7 2 0 0 2 2 2 1 AzlC protein AzlD PF05437.12 EMT54812.1 - 8.2e-16 58.0 6.6 9.7e-16 57.8 6.6 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport protein (AzlD) DUF1700 PF08006.11 EMT54812.1 - 0.023 14.2 8.4 0.037 13.5 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) PetG PF02529.15 EMT54812.1 - 0.62 10.0 4.0 2.3 8.1 4.0 1.9 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 CheW PF01584.19 EMT54813.1 - 7.5e-32 109.8 0.1 8.4e-32 109.7 0.1 1.0 1 0 0 1 1 1 1 CheW-like domain Peptidase_M23 PF01551.22 EMT54814.1 - 8.5e-16 58.0 0.0 3.2e-15 56.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M23 TruB_C PF09142.11 EMT54814.1 - 0.12 12.2 0.0 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal LigT_PEase PF02834.16 EMT54816.1 - 1.9e-24 85.6 0.0 1.1e-14 54.4 0.0 2.1 2 0 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 EMT54816.1 - 1.4e-14 54.2 0.0 1.7e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.9 EMT54816.1 - 7.1e-05 22.8 0.0 0.00012 22.1 0.0 1.3 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain SurE PF01975.17 EMT54819.1 - 5.6e-50 169.8 0.0 6.7e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE TerB PF05099.13 EMT54820.1 - 5.8e-08 32.8 0.0 4.6e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 Tellurite resistance protein TerB DUF533 PF04391.12 EMT54820.1 - 1e-05 25.2 0.0 1.2e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF533) G_glu_transpept PF01019.21 EMT54820.1 - 0.16 10.7 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase SBP_bac_5 PF00496.22 EMT54821.1 - 1.3e-41 142.9 0.0 1.7e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle SgrR_N PF12793.7 EMT54821.1 - 1.9e-24 86.1 0.3 5.8e-24 84.5 0.1 1.9 2 0 0 2 2 2 1 Sugar transport-related sRNA regulator N-term MarR PF01047.22 EMT54821.1 - 0.0042 17.0 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 EMT54821.1 - 0.014 15.3 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_36 PF13730.6 EMT54821.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FbpA PF05833.11 EMT54821.1 - 0.18 10.5 0.0 8 5.1 0.0 2.1 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) MFS_1 PF07690.16 EMT54822.1 - 2.5e-39 135.2 33.2 1.6e-24 86.5 15.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EMT54822.1 - 4.6e-14 51.7 21.0 8.2e-14 50.9 20.8 1.2 1 1 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 EMT54822.1 - 1.9e-12 46.8 24.3 3.3e-07 29.5 10.4 2.0 1 1 1 2 2 2 2 MFS_1 like family DUF2108 PF09881.9 EMT54822.1 - 0.51 10.3 5.3 1.2 9.2 0.1 3.4 3 1 0 3 3 3 0 Predicted membrane protein (DUF2108) TMEM100 PF16311.5 EMT54822.1 - 0.52 9.9 0.0 0.52 9.9 0.0 2.4 3 0 0 3 3 3 0 Transmembrane protein 100 Ilm1 PF10311.9 EMT54822.1 - 0.79 9.4 6.0 1 9.0 0.1 3.0 1 1 0 2 2 2 0 Increased loss of mitochondrial DNA protein 1 ABC_tran PF00005.27 EMT54823.1 - 2.8e-28 99.1 0.1 4.4e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT54823.1 - 6.1e-10 39.4 0.6 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMT54823.1 - 1.9e-08 34.0 3.1 1.4e-07 31.2 3.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMT54823.1 - 0.00024 20.9 2.1 0.062 13.0 0.6 2.1 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EMT54823.1 - 0.00041 20.3 0.3 0.0016 18.4 0.2 2.0 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EMT54823.1 - 0.00047 20.3 0.9 0.0034 17.5 0.9 2.0 1 1 0 1 1 1 1 Dynamin family AAA_29 PF13555.6 EMT54823.1 - 0.00083 19.1 0.2 0.0022 17.7 0.0 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain MukB PF04310.12 EMT54823.1 - 0.0021 17.9 0.1 0.0043 16.9 0.1 1.5 1 0 0 1 1 1 1 MukB N-terminal SbcCD_C PF13558.6 EMT54823.1 - 0.0061 16.8 0.2 0.11 12.7 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 EMT54823.1 - 0.0077 15.1 1.9 1.4 7.6 0.1 2.7 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 EMT54823.1 - 0.019 15.3 2.5 1.1 9.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EMT54823.1 - 0.029 14.8 4.3 0.068 13.7 4.2 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EMT54823.1 - 0.046 13.8 1.9 0.066 13.3 0.8 1.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase NAD_binding_1 PF00175.21 EMT54823.1 - 0.073 13.7 0.1 1.6 9.4 0.0 2.2 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain DUF87 PF01935.17 EMT54823.1 - 0.08 13.0 0.9 0.14 12.2 0.9 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain Zeta_toxin PF06414.12 EMT54823.1 - 0.14 11.4 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 EMT54823.1 - 0.21 12.0 0.4 1.8 9.0 0.1 2.5 2 1 1 3 3 3 0 RNA helicase BPD_transp_2 PF02653.16 EMT54824.1 - 9.9e-31 106.9 38.0 1.3e-30 106.5 38.0 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component ABC_sub_bind PF04392.12 EMT54825.1 - 1.5e-97 326.4 18.2 1.8e-97 326.2 18.2 1.0 1 0 0 1 1 1 1 ABC transporter substrate binding protein SCAB_CC PF16712.5 EMT54825.1 - 0.27 11.0 6.4 1 9.1 2.5 2.8 2 1 1 3 3 3 0 Coiled-coil regions of plant-specific actin-binding protein ABC_sub_bind PF04392.12 EMT54826.1 - 3.2e-104 348.3 9.9 3.8e-104 348.0 9.9 1.0 1 0 0 1 1 1 1 ABC transporter substrate binding protein AIRC PF00731.20 EMT54826.1 - 0.0019 17.8 0.8 0.026 14.1 0.0 2.3 1 1 1 2 2 2 1 AIR carboxylase DUF3235 PF11574.8 EMT54826.1 - 0.096 13.6 2.8 0.53 11.2 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3235) DUF21 PF01595.20 EMT54827.1 - 1.2e-52 178.1 3.4 1.7e-52 177.6 3.4 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 EMT54827.1 - 3e-20 72.0 1.4 1.5e-19 69.8 0.4 2.4 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 EMT54827.1 - 1e-16 61.1 4.2 7.7e-08 32.7 0.4 2.5 2 0 0 2 2 2 2 CBS domain ERCC3_RAD25_C PF16203.5 EMT54828.1 - 1.7e-52 178.1 0.0 2.4e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EMT54828.1 - 1.5e-39 135.0 0.2 3.4e-39 133.9 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMT54828.1 - 3.1e-12 46.8 0.0 6.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMT54828.1 - 1.9e-11 44.3 0.0 3.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EMT54828.1 - 0.00014 20.7 0.0 0.0003 19.6 0.0 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain SUKH-3 PF14433.6 EMT54828.1 - 0.051 14.0 0.0 0.89 10.0 0.0 2.8 3 0 0 3 3 3 0 SUKH-3 immunity protein Sigma70_r2 PF04542.14 EMT54829.1 - 4.3e-20 71.3 0.4 7.7e-20 70.4 0.4 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EMT54829.1 - 2.8e-11 42.9 1.2 5.3e-11 42.0 1.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EMT54829.1 - 3.5e-07 29.6 0.1 7.6e-07 28.5 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EMT54829.1 - 2.4e-05 24.3 1.4 3.7e-05 23.7 1.4 1.3 1 1 0 1 1 1 1 ECF sigma factor HTH_16 PF12645.7 EMT54829.1 - 0.0014 18.6 2.4 0.0017 18.4 1.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain DUF722 PF05263.11 EMT54829.1 - 0.023 14.9 0.1 0.088 13.0 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF722) HTH_23 PF13384.6 EMT54829.1 - 0.028 14.2 0.1 0.086 12.7 0.1 1.9 1 0 0 1 1 1 0 Homeodomain-like domain NeuB PF03102.14 EMT54829.1 - 0.061 12.8 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 NeuB family CEP209_CC5 PF16574.5 EMT54829.1 - 0.069 13.3 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 DUF134 PF02001.16 EMT54829.1 - 0.11 13.1 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_17 PF12728.7 EMT54829.1 - 0.11 12.7 0.3 0.69 10.1 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain CLTH PF10607.9 EMT54829.1 - 0.11 12.4 0.3 0.17 11.8 0.3 1.4 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain RskA PF10099.9 EMT54830.1 - 9.5e-06 26.0 10.5 9.5e-06 26.0 10.5 3.3 2 2 1 3 3 3 1 Anti-sigma-K factor rskA SOP4 PF17081.5 EMT54830.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein ABC2_membrane_2 PF12679.7 EMT54831.1 - 2e-22 79.8 20.1 4.4e-22 78.7 20.1 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 EMT54831.1 - 2.1e-14 53.9 23.7 1.9e-11 44.3 15.3 3.3 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 EMT54831.1 - 4.9e-09 36.0 0.5 4.9e-09 36.0 0.5 3.1 3 1 0 3 3 3 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 EMT54831.1 - 3e-07 29.9 9.4 3e-07 29.9 9.4 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein Trimer_CC PF08954.11 EMT54831.1 - 0.043 13.4 0.2 0.075 12.6 0.2 1.3 1 0 0 1 1 1 0 Trimerisation motif Spo7 PF03907.13 EMT54831.1 - 3.6 7.0 5.5 0.35 10.3 0.1 2.0 3 0 0 3 3 3 0 Spo7-like protein DUF2705 PF10920.8 EMT54831.1 - 8.5 5.6 17.9 1.8 7.8 10.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2705) ABC_tran PF00005.27 EMT54832.1 - 7.7e-32 110.7 0.0 1.4e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMT54832.1 - 5e-14 52.8 0.8 6e-09 36.1 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMT54832.1 - 0.0051 17.3 0.2 0.012 16.1 0.2 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMT54832.1 - 0.0067 16.7 0.1 0.027 14.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMT54832.1 - 0.0082 15.9 0.4 0.074 12.8 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_15 PF13175.6 EMT54832.1 - 0.014 15.2 0.0 6.6 6.3 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 EMT54832.1 - 0.073 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 EMT54832.1 - 0.096 13.1 0.1 0.22 12.0 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4162 PF13732.6 EMT54832.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) SbcCD_C PF13558.6 EMT54832.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Lipase_GDSL_2 PF13472.6 EMT54833.1 - 4e-27 95.7 0.1 5.1e-27 95.4 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMT54833.1 - 2.1e-20 73.6 0.1 2.4e-20 73.4 0.1 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EMT54833.1 - 0.0022 18.2 0.0 0.003 17.7 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 EMT54834.1 - 3.7e-43 147.8 43.8 1.2e-30 106.7 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMT54834.1 - 1.4e-08 34.1 33.5 3.5e-07 29.4 12.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EMT54834.1 - 1.9e-07 30.3 28.0 2.3e-06 26.7 8.2 2.2 1 1 1 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 EMT54834.1 - 2.4e-07 29.5 22.2 1.3e-06 27.1 16.1 2.3 2 1 0 2 2 2 2 Transmembrane secretion effector OGFr_N PF04664.13 EMT54834.1 - 0.24 10.9 0.1 0.37 10.3 0.1 1.2 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region S_4TM PF18159.1 EMT54834.1 - 1.8 7.8 5.7 0.34 10.2 0.6 2.3 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Lactamase_B PF00753.27 EMT54835.1 - 6.5e-14 52.4 0.0 9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMT54835.1 - 9e-08 31.9 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMT54835.1 - 0.00064 19.6 0.0 0.0011 18.8 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Oxidored_FMN PF00724.20 EMT54837.1 - 1.5e-83 280.9 0.0 2.1e-83 280.4 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 EMT54837.1 - 9.5e-29 100.5 1.4 9.5e-29 100.5 1.4 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMT54837.1 - 5.6e-13 49.3 5.3 6e-06 26.7 0.7 4.5 4 1 0 4 4 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMT54837.1 - 2.3e-12 46.8 1.1 0.00053 19.3 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMT54837.1 - 1.7e-09 37.8 0.4 6.6e-09 35.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMT54837.1 - 6.4e-09 35.0 1.7 1.7e-06 27.0 0.4 2.8 2 1 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EMT54837.1 - 2.1e-07 30.7 0.2 3.4e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMT54837.1 - 3e-07 29.9 1.2 6.7e-07 28.8 0.2 1.8 1 1 0 2 2 2 1 Thi4 family Dus PF01207.17 EMT54837.1 - 3.8e-07 29.5 0.1 6.6e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) FAD_binding_3 PF01494.19 EMT54837.1 - 6.8e-07 28.9 0.5 6.8e-07 28.9 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 EMT54837.1 - 2.3e-06 26.9 1.6 2.3e-06 26.9 1.6 2.6 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 EMT54837.1 - 1.1e-05 25.3 13.6 0.00057 19.6 13.6 3.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EMT54837.1 - 2e-05 23.9 0.4 0.00018 20.7 0.2 2.5 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 EMT54837.1 - 0.0001 21.6 0.7 0.038 13.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 EMT54837.1 - 0.00011 21.7 0.5 0.0023 17.3 0.3 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FMO-like PF00743.19 EMT54837.1 - 0.00018 20.1 0.0 0.026 13.0 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 EMT54837.1 - 0.00025 21.1 0.4 0.048 13.7 0.0 2.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SOR_SNZ PF01680.17 EMT54837.1 - 0.00026 20.8 0.5 0.072 12.9 0.2 2.3 2 0 0 2 2 2 1 SOR/SNZ family ThiF PF00899.21 EMT54837.1 - 0.0003 20.2 0.6 0.37 10.1 0.1 2.3 2 0 0 2 2 2 2 ThiF family NMO PF03060.15 EMT54837.1 - 0.00045 19.7 0.4 0.00099 18.6 0.4 1.6 1 0 0 1 1 1 1 Nitronate monooxygenase NAD_binding_7 PF13241.6 EMT54837.1 - 0.00069 20.0 1.9 0.073 13.5 0.3 3.1 3 1 0 3 3 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 EMT54837.1 - 0.0027 17.6 0.1 0.0027 17.6 0.1 2.3 3 0 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMT54837.1 - 0.0094 15.3 1.7 0.0094 15.3 1.7 2.0 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EMT54837.1 - 0.014 15.0 0.1 0.038 13.6 0.1 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 EMT54837.1 - 0.019 15.0 3.8 0.51 10.3 0.4 3.2 4 0 0 4 4 4 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 EMT54837.1 - 0.023 14.1 0.2 0.42 9.9 0.0 2.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EMT54837.1 - 0.029 14.6 0.4 0.25 11.6 0.1 2.6 3 0 0 3 3 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 EMT54837.1 - 0.034 14.1 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 EMT54837.1 - 0.039 13.0 0.9 0.12 11.4 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Ldh_1_N PF00056.23 EMT54837.1 - 0.09 12.9 0.5 7.6 6.6 0.0 3.3 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain DUF364 PF04016.12 EMT54837.1 - 0.11 12.1 0.0 0.7 9.5 0.0 2.3 2 0 0 2 2 2 0 Putative heavy-metal chelation DUF4625 PF15418.6 EMT54838.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) Nt_Gln_amidase PF09764.9 EMT54839.1 - 0.0093 15.6 0.2 0.01 15.5 0.2 1.1 1 0 0 1 1 1 1 N-terminal glutamine amidase DUF3546 PF12066.8 EMT54839.1 - 0.012 15.8 1.1 0.017 15.3 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) TUDOR PF00567.24 EMT54839.1 - 0.022 14.8 0.1 0.029 14.4 0.1 1.1 1 0 0 1 1 1 0 Tudor domain AAA_18 PF13238.6 EMT54839.1 - 0.14 12.7 0.0 0.17 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain LytR_cpsA_psr PF03816.14 EMT54840.1 - 1.8e-44 151.5 0.5 2.7e-44 151.0 0.5 1.3 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain RAG2 PF03089.14 EMT54840.1 - 0.1 11.6 0.0 0.36 9.8 0.0 1.7 2 0 0 2 2 2 0 Recombination activating protein 2 FGF-BP1 PF06473.12 EMT54840.1 - 0.16 11.7 1.9 0.28 11.0 1.9 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) NP1-WLL PF11733.8 EMT54840.1 - 1.1 9.0 5.0 0.67 9.7 0.8 2.4 3 0 0 3 3 3 0 Non-capsid protein NP1 MFS_1 PF07690.16 EMT54842.1 - 2.2e-30 105.8 34.8 2.2e-30 105.8 34.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMT54842.1 - 6.7e-10 38.4 18.8 1.1e-06 27.7 14.0 2.2 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 EMT54842.1 - 1.2e-06 27.4 21.5 4.5e-06 25.5 21.6 2.2 1 1 0 1 1 1 1 MFS/sugar transport protein OATP PF03137.20 EMT54842.1 - 1e-05 24.1 0.9 1e-05 24.1 0.9 2.8 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.19 EMT54842.1 - 0.0042 15.9 4.8 0.027 13.3 0.1 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter Sugar_tr PF00083.24 EMT54842.1 - 0.0082 15.1 24.1 0.029 13.2 12.0 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter DUF4129 PF13559.6 EMT54842.1 - 0.047 13.9 0.2 0.077 13.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Ceramidase PF05875.12 EMT54842.1 - 0.15 11.5 1.3 0.53 9.7 0.0 2.3 2 0 0 2 2 2 0 Ceramidase SEC-C PF02810.15 EMT54843.1 - 1.7e-09 37.4 11.7 2.6e-09 36.8 11.7 1.3 1 0 0 1 1 1 1 SEC-C motif Abhydrolase_3 PF07859.13 EMT54843.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2730 PF10805.8 EMT54844.1 - 0.01 15.9 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) 7tm_6 PF02949.20 EMT54844.1 - 0.015 14.4 0.6 0.017 14.2 0.6 1.1 1 0 0 1 1 1 0 7tm Odorant receptor Nup54 PF13874.6 EMT54844.1 - 0.026 14.6 1.9 0.028 14.5 1.9 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 NFRKB_winged PF14465.6 EMT54844.1 - 0.044 14.0 0.3 0.19 12.0 0.3 1.8 1 1 0 1 1 1 0 NFRKB Winged Helix-like CCDC53 PF10152.9 EMT54845.1 - 0.19 12.1 8.4 0.37 11.2 8.4 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TCP PF03634.13 EMT54845.1 - 6.4 7.3 9.3 15 6.1 9.3 1.6 1 0 0 1 1 1 0 TCP family transcription factor Cadherin-like PF12733.7 EMT54846.1 - 0.24 12.0 2.0 6.1 7.4 0.2 3.1 3 0 0 3 3 3 0 Cadherin-like beta sandwich domain HD PF01966.22 EMT54847.1 - 1.2e-07 31.9 0.2 2.3e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 HD domain tRNA_anti-codon PF01336.25 EMT54847.1 - 4.3e-06 26.6 0.1 1e-05 25.4 0.1 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain HD_6 PF18019.1 EMT54847.1 - 0.0054 16.9 0.2 0.02 15.0 0.2 1.9 1 1 0 1 1 1 1 HD domain DUF1232 PF06803.12 EMT54848.1 - 3.2e-11 42.8 4.3 6.9e-11 41.8 4.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) SNARE_assoc PF09335.11 EMT54849.1 - 4.7e-20 72.3 8.9 4.7e-20 72.3 8.9 2.3 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF4059 PF13268.6 EMT54849.1 - 0.021 15.2 0.4 0.058 13.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) DUF5337 PF17272.2 EMT54849.1 - 0.18 11.7 6.4 0.38 10.6 4.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5337) DUF2062 PF09835.9 EMT54850.1 - 4.9e-29 101.1 5.6 5.6e-29 100.9 5.6 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) DUF202 PF02656.15 EMT54850.1 - 1.4 9.4 4.1 4.4 7.8 3.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2207 PF09972.9 EMT54850.1 - 2.4 6.8 4.5 9.4 4.9 0.9 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) NAD_synthase PF02540.17 EMT54852.1 - 1.2e-65 221.0 0.0 1.6e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 EMT54852.1 - 0.0015 17.4 0.0 0.0092 14.8 0.0 2.0 2 0 0 2 2 2 1 tRNA methyl transferase GlutR_N PF05201.15 EMT54852.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain Peptidase_M24 PF00557.24 EMT54853.1 - 1e-55 188.7 0.2 1.1e-55 188.5 0.2 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3215 PF11503.8 EMT54853.1 - 0.14 12.1 0.1 1.2 9.0 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3215) BLOC1_2 PF10046.9 EMT54854.1 - 0.013 15.8 1.0 0.015 15.6 1.0 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4635 PF15466.6 EMT54854.1 - 0.049 13.2 1.5 0.053 13.0 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Fzo_mitofusin PF04799.13 EMT54854.1 - 0.053 13.1 2.3 0.06 12.9 2.3 1.0 1 0 0 1 1 1 0 fzo-like conserved region Paralemmin PF03285.15 EMT54854.1 - 0.059 12.9 3.0 0.065 12.8 3.0 1.1 1 0 0 1 1 1 0 Paralemmin DUF1664 PF07889.12 EMT54854.1 - 0.067 13.2 1.2 0.075 13.1 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) KxDL PF10241.9 EMT54854.1 - 0.085 13.1 2.9 0.11 12.8 2.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein UPF0449 PF15136.6 EMT54854.1 - 0.37 11.3 4.9 0.52 10.8 3.6 1.8 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 PspC PF04024.12 EMT54855.1 - 2.4e-17 62.5 1.9 3.1e-17 62.1 1.9 1.2 1 0 0 1 1 1 1 PspC domain DUF2935 PF11155.8 EMT54857.1 - 2.3e-16 60.2 0.2 2.9e-16 59.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) Flavin_Reduct PF01613.18 EMT54858.1 - 7.5e-26 91.0 0.1 9.8e-26 90.6 0.1 1.0 1 0 0 1 1 1 1 Flavin reductase like domain HgmA PF04209.13 EMT54859.1 - 4.2e-25 88.3 0.3 1e-24 87.0 0.3 1.5 1 1 0 1 1 1 1 homogentisate 1,2-dioxygenase Cupin_2 PF07883.11 EMT54859.1 - 4.6e-06 26.2 0.9 0.00014 21.5 0.0 3.0 3 0 0 3 3 3 1 Cupin domain FAA_hydrolase PF01557.18 EMT54860.1 - 6.9e-60 202.4 0.0 8.3e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydro_N_2 PF18288.1 EMT54860.1 - 0.0038 17.6 0.1 0.008 16.6 0.1 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal domain 2 PseudoU_synth_2 PF00849.22 EMT54861.1 - 2.3e-37 128.5 0.1 3.2e-37 128.1 0.1 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase MoeA_C PF03454.15 EMT54861.1 - 0.083 13.1 0.4 3.5 7.9 0.0 3.3 4 0 0 4 4 4 0 MoeA C-terminal region (domain IV) Peptidase_S66 PF02016.15 EMT54863.1 - 1.2e-32 112.6 0.0 1.8e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 EMT54863.1 - 1.7e-31 109.3 0.0 1.4e-30 106.3 0.0 2.0 2 0 0 2 2 2 1 LD-carboxypeptidase C-terminal domain Redoxin PF08534.10 EMT54864.1 - 2.6e-22 79.1 0.1 3.2e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EMT54864.1 - 4.4e-17 62.2 0.0 5.4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family GGACT PF06094.12 EMT54866.1 - 3.7e-24 85.6 0.1 4.2e-24 85.5 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like CPSase_L_D2 PF02786.17 EMT54867.1 - 3.2e-81 271.9 0.1 1e-80 270.2 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EMT54867.1 - 2.1e-77 259.4 0.0 3.4e-77 258.7 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EMT54867.1 - 2.1e-41 140.9 0.5 5.1e-41 139.7 0.1 2.0 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain HMGL-like PF00682.19 EMT54867.1 - 2.4e-31 109.2 0.0 4.6e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.19 EMT54867.1 - 3.3e-31 107.6 0.0 9.8e-31 106.1 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EMT54867.1 - 9.9e-19 67.0 0.9 1.7e-17 63.0 2.4 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EMT54867.1 - 5e-11 42.2 0.2 5.7e-06 26.1 0.0 3.0 2 0 0 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EMT54867.1 - 1.1e-10 41.4 0.0 2.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EMT54867.1 - 4.9e-10 39.2 0.0 1.7e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EMT54867.1 - 1.1e-06 28.8 0.0 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EMT54867.1 - 0.00049 19.7 0.0 0.00097 18.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 EMT54867.1 - 0.0012 18.7 0.1 0.004 17.1 0.1 1.9 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 EMT54867.1 - 0.0047 17.6 0.0 0.17 12.6 0.0 2.9 3 0 0 3 3 3 1 HlyD family secretion protein HlyD_D23 PF16576.5 EMT54867.1 - 0.014 14.6 0.1 1.9 7.7 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion NQRA PF05896.11 EMT54867.1 - 0.018 14.5 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ADH_zinc_N PF00107.26 EMT54867.1 - 0.019 14.9 0.0 5.4 7.0 0.0 2.9 3 0 0 3 3 2 0 Zinc-binding dehydrogenase PTS_EIIA_1 PF00358.20 EMT54867.1 - 0.028 14.2 0.3 10 5.9 0.0 3.0 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ATPgrasp_ST PF14397.6 EMT54867.1 - 0.12 11.6 0.0 0.35 10.1 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 EMT54867.1 - 0.16 11.8 0.1 0.38 10.7 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein FliD_C PF07195.12 EMT54868.1 - 1.8e-06 27.6 0.0 0.013 14.9 0.0 2.3 1 1 1 2 2 2 2 Flagellar hook-associated protein 2 C-terminus FliD_N PF02465.18 EMT54868.1 - 3.7e-05 24.3 0.0 8.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus Spore_YtfJ PF09579.10 EMT54869.1 - 1.3e-30 105.4 1.3 1.4e-30 105.3 0.3 1.5 2 0 0 2 2 2 1 Sporulation protein YtfJ (Spore_YtfJ) DUF2953 PF11167.8 EMT54870.1 - 3.6e-12 46.2 0.3 6.4e-12 45.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2953) DUF382 PF04037.13 EMT54870.1 - 0.1 12.8 0.2 0.16 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF382) ANAPC4_WD40 PF12894.7 EMT54870.1 - 0.12 12.6 0.1 11 6.4 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SLH PF00395.20 EMT54871.1 - 2.5e-26 91.4 0.0 2.4e-08 33.8 0.0 3.9 3 0 0 3 3 3 3 S-layer homology domain 3D PF06725.11 EMT54871.1 - 3.5e-17 62.4 0.5 5.9e-17 61.6 0.5 1.4 1 0 0 1 1 1 1 3D domain YkuD PF03734.14 EMT54872.1 - 9.2e-20 71.5 0.2 2.4e-19 70.2 0.2 1.6 1 1 0 1 1 1 1 L,D-transpeptidase catalytic domain PG_binding_1 PF01471.18 EMT54872.1 - 1.2e-12 47.8 0.1 1.9e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_2 PF08823.11 EMT54872.1 - 0.00041 20.6 0.0 0.00092 19.5 0.0 1.5 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Hydrolase_2 PF07486.12 EMT54873.1 - 4.4e-28 98.2 0.1 7.8e-28 97.4 0.1 1.4 1 0 0 1 1 1 1 Cell Wall Hydrolase PG_binding_1 PF01471.18 EMT54873.1 - 1.8e-15 56.8 0.3 3.8e-15 55.8 0.3 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 EMT54873.1 - 0.014 15.6 0.2 1 9.7 0.1 2.4 1 1 1 2 2 2 0 Predicted Peptidoglycan domain WW PF00397.26 EMT54873.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 WW domain YceG PF02618.16 EMT54873.1 - 0.041 13.4 0.1 0.089 12.3 0.1 1.5 1 1 0 1 1 1 0 YceG-like family SpoVAC_SpoVAEB PF03862.13 EMT54874.1 - 1.8e-41 141.0 10.9 2e-41 140.8 10.9 1.0 1 0 0 1 1 1 1 SpoVAC/SpoVAEB sporulation membrane protein SpoVAD PF07451.11 EMT54875.1 - 2.8e-155 516.0 0.0 3.1e-155 515.8 0.0 1.0 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) Thiolase_N PF00108.23 EMT54875.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EMT54875.1 - 0.45 10.4 2.6 63 3.5 2.5 3.2 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAC_SpoVAEB PF03862.13 EMT54876.1 - 1.2e-39 135.2 8.8 1.4e-39 134.9 8.8 1.1 1 0 0 1 1 1 1 SpoVAC/SpoVAEB sporulation membrane protein DUF2157 PF09925.9 EMT54876.1 - 0.018 14.8 1.5 3.6 7.4 0.2 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) SecE PF00584.20 EMT54876.1 - 0.24 11.4 3.2 4.3 7.3 2.3 2.4 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex DUF421 PF04239.12 EMT54877.1 - 1.1e-34 118.4 0.4 2.4e-34 117.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF421) DUF1657 PF07870.11 EMT54877.1 - 2.8e-16 59.1 4.8 4.6e-16 58.4 4.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1657) DUF4443 PF14544.6 EMT54877.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) DUF1657 PF07870.11 EMT54878.1 - 9.6e-24 83.0 8.9 1.2e-23 82.7 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1657) DUF2383 PF09537.10 EMT54878.1 - 0.0013 19.1 1.2 0.0013 19.0 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) SbcD_C PF12320.8 EMT54878.1 - 0.017 15.4 0.2 0.019 15.2 0.2 1.1 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Coat_F PF07875.12 EMT54878.1 - 0.042 14.1 3.0 0.07 13.4 2.9 1.4 1 1 0 1 1 1 0 Coat F domain DUF2802 PF10975.8 EMT54878.1 - 0.12 12.5 8.8 1.1 9.5 4.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) H-kinase_dim PF02895.14 EMT54878.1 - 0.15 12.5 4.3 0.21 12.0 4.3 1.3 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DUF2203 PF09969.9 EMT54878.1 - 0.15 12.8 1.7 0.16 12.7 1.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Prominin PF05478.11 EMT54878.1 - 0.17 9.8 4.5 0.18 9.7 4.5 1.0 1 0 0 1 1 1 0 Prominin SSTK-IP PF15836.5 EMT54878.1 - 1.6 8.9 7.7 5.1 7.3 7.7 1.8 1 1 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein SASP PF00269.20 EMT54879.1 - 3e-24 84.8 0.0 3.6e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Small, acid-soluble spore proteins, alpha/beta type MGDG_synth PF06925.11 EMT54880.1 - 6.4e-22 78.5 0.0 9.8e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 EMT54880.1 - 1.3e-08 35.0 0.0 2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.20 EMT54880.1 - 1.1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMT54880.1 - 3.3e-05 24.3 0.0 8.3e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMT54880.1 - 0.00059 19.9 0.6 0.0012 18.9 0.6 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Epimerase_2 PF02350.19 EMT54880.1 - 0.0034 16.3 0.0 0.0068 15.3 0.0 1.5 2 0 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 EMT54880.1 - 0.22 11.9 5.3 0.6 10.5 5.3 1.9 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain DUF1106 PF06523.11 EMT54881.1 - 0.0042 17.1 0.1 0.52 10.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1106) TerC PF03741.16 EMT54882.1 - 1.9e-44 151.5 3.8 2.3e-44 151.2 3.8 1.1 1 0 0 1 1 1 1 Integral membrane protein TerC family MarC PF01914.17 EMT54882.1 - 9e-05 21.9 0.4 0.00019 20.9 0.1 1.8 1 1 1 2 2 2 1 MarC family integral membrane protein DUF3099 PF11298.8 EMT54882.1 - 0.29 11.3 2.6 0.39 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) HATPase_c PF02518.26 EMT54883.1 - 1.7e-22 80.0 0.0 2.8e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EMT54883.1 - 1.3e-11 44.3 0.0 3.1e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 GHKL domain HisKA PF00512.25 EMT54883.1 - 1.2e-10 41.3 0.0 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Brevibacillus_borstelensis_AK1-ASM35356v1/GCA_000353565.1_ASM35356v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Brevibacillus_borstelensis_AK1-ASM35356v1/GCA_000353565.1_ASM35356v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Brevibacillus_borstelensis_AK1-ASM35356v1/GCA_000353565.1_ASM35356v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Brevibacillus_borstelensis_AK1-ASM35356v1/GCA_000353565.1_ASM35356v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 02:24:02 2019 # [ok]