# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF2248 PF10005.4 AJZ75045.1 - 0.00019 20.4 3.0 0.00043 19.3 2.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2248) Plasmid_stabil PF05016.9 AJZ75046.1 - 5.1e-13 49.2 0.1 5.7e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Plasmid stabilisation system protein KH_2 PF07650.12 AJZ75046.1 - 0.044 13.3 0.7 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 KH domain Gag_p24 PF00607.15 AJZ75047.1 - 0.011 15.2 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) V-ATPase_G PF03179.10 AJZ75047.1 - 0.021 15.1 0.8 0.064 13.5 0.1 1.8 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF217 PF02697.9 AJZ75047.1 - 0.045 14.0 1.2 0.066 13.4 0.8 1.5 1 1 0 1 1 1 0 Uncharacterized ACR, COG1753 RNA_pol_A_CTD PF03118.10 AJZ75047.1 - 0.047 13.1 2.4 0.3 10.5 0.1 2.4 2 1 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain QRPTase_C PF01729.14 AJZ75048.1 - 4.7e-53 179.1 1.4 6.4e-53 178.7 1.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 AJZ75048.1 - 2e-25 88.4 0.3 6.1e-25 86.8 0.1 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.14 AJZ75048.1 - 0.00074 18.6 0.1 0.0016 17.5 0.1 1.6 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.12 AJZ75048.1 - 0.023 13.7 0.1 0.05 12.7 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Spt4 PF06093.8 AJZ75049.1 - 1.5e-12 47.2 0.5 2e-12 46.8 0.3 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-RING_6 PF14835.1 AJZ75049.1 - 0.075 12.8 1.2 0.085 12.6 0.8 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Sar8_2 PF03058.9 AJZ75049.1 - 0.11 12.8 1.4 0.16 12.3 1.0 1.3 1 0 0 1 1 1 0 Sar8.2 family ParA PF10609.4 AJZ75050.1 - 3.7e-36 122.8 0.2 1.8e-35 120.6 0.1 2.1 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 AJZ75050.1 - 7.7e-20 71.1 0.1 1.2e-19 70.5 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF59 PF01883.14 AJZ75050.1 - 1.3e-19 69.9 1.3 1e-18 67.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF59 AAA_31 PF13614.1 AJZ75050.1 - 1.4e-11 44.5 0.1 5.5e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 AJZ75050.1 - 1e-08 34.5 0.0 1.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 AJZ75050.1 - 1.4e-07 30.9 0.0 0.0002 20.6 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 AJZ75050.1 - 2.3e-05 23.5 0.7 2.3e-05 23.5 0.5 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.1 AJZ75050.1 - 0.00014 21.5 0.2 0.36 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain VirC1 PF07015.6 AJZ75050.1 - 0.00078 18.5 0.1 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 VirC1 protein AAA_25 PF13481.1 AJZ75050.1 - 0.011 15.1 0.4 0.028 13.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 AJZ75050.1 - 0.016 13.9 0.3 0.025 13.3 0.2 1.3 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 AJZ75050.1 - 0.071 12.5 0.3 0.19 11.1 0.1 1.7 2 0 0 2 2 2 0 AAA-like domain APS_kinase PF01583.15 AJZ75050.1 - 0.087 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF359 PF04019.7 AJZ75051.1 - 2.3e-34 117.3 0.0 2.9e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF359) Pyrophosphatase PF00719.14 AJZ75052.1 - 9.8e-59 197.2 0.3 1.1e-58 197.0 0.2 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase SprT-like PF10263.4 AJZ75053.1 - 9.3e-05 22.1 0.0 0.00011 21.9 0.0 1.1 1 0 0 1 1 1 1 SprT-like family DUF45 PF01863.12 AJZ75053.1 - 0.00019 21.2 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_MA_2 PF13485.1 AJZ75053.1 - 0.021 14.8 0.0 0.036 14.1 0.0 1.4 1 1 0 1 1 1 0 Peptidase MA superfamily Peptidase_M76 PF09768.4 AJZ75053.1 - 0.022 14.2 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase M76 family Sigma70_r3 PF04539.11 AJZ75054.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 region 3 UPF0262 PF06793.7 AJZ75055.1 - 0.079 12.6 0.0 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Cyclophil_like PF04126.8 AJZ75056.1 - 5.5e-34 116.3 0.0 6.1e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin-like Prok-JAB PF14464.1 AJZ75057.1 - 1.7e-19 69.3 0.0 2e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.16 AJZ75057.1 - 1.1e-10 41.2 0.0 1.9e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Toxin-JAB1 PF15659.1 AJZ75057.1 - 0.034 14.0 0.1 0.036 13.9 0.1 1.2 1 0 0 1 1 1 0 JAB-like toxin 1 RadC PF04002.10 AJZ75057.1 - 0.081 12.6 0.6 0.15 11.7 0.3 1.9 1 1 1 2 2 2 0 RadC-like JAB domain UbiA PF01040.13 AJZ75058.1 - 5.2e-29 101.2 24.6 6.5e-29 100.9 17.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1129 PF06570.6 AJZ75058.1 - 0.064 12.5 10.7 0.55 9.5 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3593 PF12159.3 AJZ75058.1 - 2.1 8.1 8.1 1.4 8.7 0.0 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF3593) Cnd2 PF05786.9 AJZ75059.1 - 0.0039 15.7 0.1 0.0044 15.6 0.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF1456 PF07308.8 AJZ75059.1 - 0.022 14.7 2.3 0.095 12.7 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1456) EF1_GNE PF00736.14 AJZ75060.1 - 1.6e-17 62.9 0.0 1.8e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain DAO PF01266.19 AJZ75061.1 - 1e-07 31.1 1.1 6.1e-05 22.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AJZ75061.1 - 6.3e-07 28.7 4.6 4.9e-05 22.5 1.5 3.0 1 1 1 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 AJZ75061.1 - 6.6e-06 25.2 0.0 0.0016 17.4 0.1 2.3 2 1 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 AJZ75061.1 - 1.4e-05 25.0 0.4 3.2e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AJZ75061.1 - 2e-05 23.2 1.2 6.2e-05 21.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 AJZ75061.1 - 4.6e-05 22.4 0.4 8.4e-05 21.5 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 AJZ75061.1 - 0.00013 21.1 0.3 0.00027 20.1 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 AJZ75061.1 - 0.00013 21.1 0.1 0.00019 20.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AJZ75061.1 - 0.0016 18.3 0.5 0.0053 16.7 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 AJZ75061.1 - 0.0086 14.7 0.1 1.8 7.0 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_7 PF13241.1 AJZ75061.1 - 0.032 14.4 1.0 0.097 12.9 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 AJZ75061.1 - 0.15 12.4 2.9 2.6 8.5 0.2 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PTH2 PF01981.11 AJZ75062.1 - 2.9e-44 149.4 0.1 3.2e-44 149.3 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SGL PF08450.7 AJZ75063.1 - 5.2e-09 35.8 3.1 0.52 9.6 0.0 4.6 3 2 1 4 4 4 4 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 AJZ75063.1 - 0.01 15.7 0.4 0.58 10.2 0.0 3.3 3 0 0 3 3 3 0 NHL repeat Reg_prop PF07494.6 AJZ75063.1 - 0.19 11.8 3.7 18 5.8 0.0 3.8 3 0 0 3 3 3 0 Two component regulator propeller TruD PF01142.13 AJZ75064.1 - 2.5e-64 217.3 0.0 2.7e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Glycos_transf_2 PF00535.21 AJZ75065.1 - 6.7e-33 113.7 0.0 1.8e-32 112.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 GtrA PF04138.9 AJZ75065.1 - 4.7e-21 74.9 11.8 7.6e-21 74.2 7.1 2.1 2 1 0 2 2 2 1 GtrA-like protein Glyco_tranf_2_3 PF13641.1 AJZ75065.1 - 2.7e-09 37.1 0.0 3.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 AJZ75065.1 - 4.4e-06 25.9 0.1 6.8e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AJZ75065.1 - 0.0025 17.0 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 NTP_transf_3 PF12804.2 AJZ75065.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain NHL PF01436.16 AJZ75067.1 - 9.5e-35 116.8 1.0 4.7e-06 26.2 0.0 7.3 8 0 0 8 8 8 5 NHL repeat AhpC-TSA PF00578.16 AJZ75067.1 - 3e-13 49.5 0.0 8e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 AJZ75067.1 - 1e-12 47.9 0.0 2.6e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 AJZ75067.1 - 1.2e-11 44.3 0.0 2.8e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 AJZ75067.1 - 7e-06 26.2 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 AJZ75067.1 - 0.00036 20.1 0.0 0.05 13.2 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin SGL PF08450.7 AJZ75067.1 - 0.00082 18.8 0.4 0.65 9.3 0.1 4.1 3 1 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region PQQ_3 PF13570.1 AJZ75067.1 - 0.014 15.6 10.1 0.96 9.8 0.5 5.9 5 1 1 6 6 6 0 PQQ-like domain OLF PF02191.11 AJZ75067.1 - 0.018 14.3 0.2 17 4.5 0.0 3.9 2 2 2 4 4 4 0 Olfactomedin-like domain AsnC_trans_reg PF01037.16 AJZ75068.1 - 8.7e-12 44.5 0.2 9.5e-12 44.4 0.1 1.0 1 0 0 1 1 1 1 AsnC family GYD PF08734.6 AJZ75068.1 - 0.0025 17.4 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 GYD domain Tup_N PF08581.5 AJZ75068.1 - 0.051 13.7 1.1 0.28 11.3 0.3 1.9 1 1 1 2 2 2 0 Tup N-terminal DUF2561 PF10812.3 AJZ75069.1 - 0.0034 17.0 0.2 0.0037 16.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) DUF4536 PF15055.1 AJZ75069.1 - 0.047 13.7 0.7 0.047 13.7 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) ABC2_membrane_4 PF12730.2 AJZ75069.1 - 0.18 10.9 2.4 0.19 10.8 1.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2905 PF11146.3 AJZ75069.1 - 2.5 8.0 6.8 1.1 9.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) HMG_box_2 PF09011.5 AJZ75070.1 - 0.0051 17.1 0.3 0.013 15.8 0.2 1.8 1 0 0 1 1 1 1 HMG-box domain SYF2 PF08231.7 AJZ75070.1 - 0.21 11.6 4.8 0.12 12.4 1.9 1.6 1 1 0 1 1 1 0 SYF2 splicing factor Vps54 PF07928.7 AJZ75070.1 - 0.99 9.5 4.4 6.6 6.8 0.1 2.2 1 1 1 2 2 2 0 Vps54-like protein PMT_2 PF13231.1 AJZ75071.1 - 7e-17 61.7 20.7 7e-17 61.7 14.4 2.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.13 AJZ75071.1 - 5.2e-09 35.8 18.3 5.2e-09 35.8 12.7 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase EpsG PF14897.1 AJZ75071.1 - 4.9e-05 22.4 37.5 0.00041 19.3 15.7 2.2 2 0 0 2 2 2 2 EpsG family DUF3506 PF12014.3 AJZ75071.1 - 0.039 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) DUF2029 PF09594.5 AJZ75071.1 - 0.33 10.4 14.2 0.012 15.1 5.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) Viral_Beta_CD PF04530.7 AJZ75073.1 - 0.026 14.6 0.1 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Viral Beta C/D like family MutS_II PF05188.12 AJZ75075.1 - 0.067 13.2 0.1 0.075 13.1 0.1 1.1 1 0 0 1 1 1 0 MutS domain II NPV_P10 PF05531.7 AJZ75075.1 - 0.33 11.2 2.1 4.6 7.5 0.1 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SpoOE-like PF09388.5 AJZ75076.1 - 0.09 12.3 0.9 8 6.0 0.1 2.5 2 1 0 2 2 2 0 Spo0E like sporulation regulatory protein Chordopox_A30L PF06015.7 AJZ75076.1 - 0.096 12.2 2.7 6 6.5 0.6 2.4 1 1 1 2 2 2 0 Chordopoxvirus A30L protein Dimerisation PF08100.6 AJZ75076.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Dimerisation domain Thioredox_DsbH PF03190.10 AJZ75077.1 - 3.3e-77 257.7 0.3 5.4e-77 257.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 AJZ75077.1 - 1.4e-14 53.8 0.0 3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.8 AJZ75077.1 - 6.2e-09 35.4 4.1 0.00085 18.6 0.2 3.4 3 0 0 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_76 PF03663.9 AJZ75077.1 - 2.3e-05 23.9 2.3 6.7e-05 22.4 0.7 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 AJZ75077.1 - 3.3e-05 23.0 0.2 0.22 10.5 0.2 3.1 2 2 0 2 2 2 2 Glycosyl Hydrolase Family 88 Thioredoxin_2 PF13098.1 AJZ75077.1 - 0.00022 21.3 0.0 0.00057 20.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain GlcNAc_2-epim PF07221.6 AJZ75077.1 - 0.0003 19.9 0.9 0.23 10.4 0.4 2.7 2 1 0 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF1680 PF07944.7 AJZ75077.1 - 0.01 14.1 3.0 0.033 12.4 0.2 2.4 2 1 1 3 3 3 0 Putative glycosyl hydrolase of unknown function (DUF1680) ACP_syn_III_C PF08541.5 AJZ75077.1 - 0.14 12.2 0.0 3.2 7.8 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal TOBE_3 PF12857.2 AJZ75078.1 - 0.077 12.8 0.1 1.7 8.5 0.0 2.6 2 1 0 2 2 2 0 TOBE-like domain FATC PF02260.15 AJZ75079.1 - 0.12 11.8 0.6 0.23 10.9 0.4 1.4 1 0 0 1 1 1 0 FATC domain DUF4296 PF14129.1 AJZ75079.1 - 0.39 10.8 4.4 0.2 11.8 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) DUF2681 PF10883.3 AJZ75081.1 - 0.026 14.7 0.2 0.18 12.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF3316 PF11777.3 AJZ75081.1 - 0.064 13.0 0.4 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) MLANA PF14991.1 AJZ75081.1 - 0.072 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A A2M_N PF01835.14 AJZ75082.1 - 2.2e-07 31.0 0.1 6.3e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 MG2 domain B_lectin PF01453.19 AJZ75082.1 - 0.026 14.4 0.2 0.059 13.2 0.0 1.7 2 0 0 2 2 2 0 D-mannose binding lectin AsnC_trans_reg PF01037.16 AJZ75084.1 - 6.8e-13 48.1 0.1 7.2e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 AsnC family GYD PF08734.6 AJZ75084.1 - 0.031 13.9 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 GYD domain ATG22 PF11700.3 AJZ75085.1 - 0.13 10.7 4.0 0.16 10.4 2.8 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Abi PF02517.11 AJZ75086.1 - 0.039 14.0 4.9 0.039 14.0 3.4 2.9 2 1 1 3 3 3 0 CAAX protease self-immunity PvlArgDC PF01862.11 AJZ75087.1 - 6.7e-60 201.4 0.0 7.4e-60 201.2 0.0 1.0 1 0 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Peptidase_M3 PF01432.15 AJZ75088.1 - 3.4e-42 145.0 0.9 6e-42 144.2 0.6 1.4 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.5 AJZ75088.1 - 6.4e-08 32.5 0.3 3e-07 30.3 0.1 2.2 2 0 0 2 2 2 1 Oligopeptidase F Peptidase_MA_2 PF13485.1 AJZ75088.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily DUF955 PF06114.8 AJZ75088.1 - 0.03 14.0 0.0 0.091 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF955) HTH_45 PF14947.1 AJZ75089.1 - 5e-08 32.6 1.9 6.3e-08 32.3 1.3 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.17 AJZ75089.1 - 0.00041 19.9 0.1 0.00063 19.3 0.1 1.3 1 0 0 1 1 1 1 MarR family DUF505 PF04458.7 AJZ75089.1 - 0.025 12.7 0.1 0.028 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) TrmB PF01978.14 AJZ75089.1 - 0.043 13.5 0.1 0.066 12.9 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 AJZ75089.1 - 0.046 13.1 0.4 0.071 12.5 0.3 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2250 PF10007.4 AJZ75089.1 - 0.07 13.0 0.4 0.11 12.4 0.3 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PadR PF03551.9 AJZ75089.1 - 0.089 12.5 0.1 0.2 11.4 0.0 1.5 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family YbgT_YccB PF08173.6 AJZ75090.1 - 0.091 12.5 2.4 0.14 12.0 1.2 1.7 1 1 0 1 1 1 0 Membrane bound YbgT-like protein DUF2207 PF09972.4 AJZ75090.1 - 0.16 10.5 1.6 0.18 10.3 1.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1049 PF06305.6 AJZ75090.1 - 0.49 9.9 4.1 0.38 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Cupredoxin_1 PF13473.1 AJZ75091.1 - 1.3e-09 37.9 0.1 1.7e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain COX2 PF00116.15 AJZ75091.1 - 0.054 13.3 0.1 0.066 13.0 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain Copper-bind PF00127.15 AJZ75091.1 - 0.16 12.2 0.7 0.4 10.9 0.4 1.7 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Response_reg PF00072.19 AJZ75092.1 - 2.1e-18 66.3 0.0 2.3e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.14 AJZ75092.1 - 0.0028 17.5 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain DUF356 PF04009.7 AJZ75092.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF356) WSN PF02206.13 AJZ75092.1 - 0.12 12.1 0.4 0.28 10.9 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function ADH_zinc_N PF00107.21 AJZ75094.1 - 8.8e-29 99.6 0.0 1.4e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AJZ75094.1 - 1.5e-21 76.1 0.0 2.6e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AJZ75094.1 - 4.8e-17 63.0 0.0 7.8e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.5 AJZ75094.1 - 0.012 15.6 0.2 0.03 14.3 0.0 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Aldo_ket_red PF00248.16 AJZ75095.1 - 1e-52 178.7 0.0 1.1e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MCPsignal PF00015.16 AJZ75096.1 - 6.3e-52 176.2 67.6 9.9e-49 165.7 26.2 4.0 3 1 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.20 AJZ75096.1 - 5.8e-12 45.6 13.7 1.1e-11 44.6 0.0 4.4 6 1 0 6 6 6 2 HAMP domain Cache_3 PF14827.1 AJZ75096.1 - 0.0012 18.7 0.1 0.0012 18.7 0.0 3.7 4 1 0 4 4 4 1 Sensory domain of two-component sensor kinase Cache_1 PF02743.13 AJZ75096.1 - 0.0051 16.3 0.5 0.79 9.3 0.0 3.9 4 0 0 4 4 4 1 Cache domain Hormone_1 PF00103.15 AJZ75096.1 - 1.9 7.7 23.9 0.025 13.9 1.7 4.9 3 2 3 6 6 6 0 Somatotropin hormone family MCPsignal PF00015.16 AJZ75098.1 - 1.9e-11 43.9 0.6 2.9e-11 43.3 0.4 1.2 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Cache_1 PF02743.13 AJZ75098.1 - 0.027 14.0 0.3 0.25 10.9 0.0 2.6 3 1 0 3 3 3 0 Cache domain TerC PF03741.11 AJZ75099.1 - 6.8e-54 182.0 12.9 1e-53 181.5 7.7 2.0 2 0 0 2 2 2 1 Integral membrane protein TerC family DUF475 PF04332.10 AJZ75099.1 - 0.00092 18.8 14.1 0.0053 16.3 9.3 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF475) TauE PF01925.14 AJZ75099.1 - 0.15 11.4 27.0 3.2 7.1 3.5 3.3 1 1 2 3 3 3 0 Sulfite exporter TauE/SafE DUF3464 PF11947.3 AJZ75099.1 - 4.1 6.8 6.1 3.2 7.1 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) CxxCxxCC PF03692.10 AJZ75100.1 - 5.5e-08 33.1 3.9 8.1e-08 32.6 2.7 1.3 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain DUF4284 PF14112.1 AJZ75100.1 - 0.0092 16.4 0.1 0.038 14.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4284) Auto_anti-p27 PF06677.7 AJZ75101.1 - 0.0011 18.6 0.6 1.4 8.7 0.1 2.1 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.2 AJZ75101.1 - 0.0072 16.1 0.6 0.0086 15.8 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4_3 PF13920.1 AJZ75101.1 - 0.028 14.1 1.7 0.03 13.9 1.2 1.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_3 PF13878.1 AJZ75101.1 - 0.049 13.2 1.7 0.051 13.1 0.7 1.4 1 1 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO zf-RING_4 PF14570.1 AJZ75101.1 - 0.051 13.1 1.8 0.071 12.6 1.2 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CTV_P23 PF04808.7 AJZ75101.1 - 0.13 11.5 0.8 0.14 11.4 0.6 1.0 1 0 0 1 1 1 0 Citrus tristeza virus (CTV) P23 protein Ribosomal_L40e PF01020.12 AJZ75101.1 - 0.25 10.9 6.6 2.9 7.5 4.7 2.0 1 1 1 2 2 2 0 Ribosomal L40e family zinc_ribbon_2 PF13240.1 AJZ75101.1 - 0.32 10.5 1.6 1.3 8.5 1.3 1.8 1 1 1 2 2 2 0 zinc-ribbon domain zf-RanBP PF00641.13 AJZ75101.1 - 0.38 9.9 3.7 0.53 9.4 2.5 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DNA_RNApol_7kD PF03604.8 AJZ75101.1 - 1 8.8 5.6 2.2 7.8 3.9 1.7 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit ATP-grasp_2 PF08442.5 AJZ75102.1 - 2e-43 148.1 0.6 4.2e-43 147.1 0.4 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 AJZ75102.1 - 1.6e-14 53.6 0.2 6.5e-14 51.6 0.1 2.0 1 1 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 AJZ75102.1 - 8.6e-14 51.4 1.0 1.9e-13 50.3 0.7 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_4 PF13535.1 AJZ75102.1 - 1.4e-06 28.1 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AJZ75102.1 - 1.8e-05 24.1 0.0 3.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 AJZ75102.1 - 0.0001 21.7 0.1 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain AdoHcyase_NAD PF00670.16 AJZ75103.1 - 0.052 13.3 0.0 0.063 13.1 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain tRNA-synt_1 PF00133.17 AJZ75104.1 - 7.6e-145 483.2 0.1 1e-144 482.8 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AJZ75104.1 - 5.9e-28 97.5 0.4 1.4e-27 96.3 0.3 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AJZ75104.1 - 3e-25 88.6 0.7 1.9e-10 39.9 0.1 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 AJZ75104.1 - 2.2e-06 27.0 0.0 3.2e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 AJZ75104.1 - 0.00034 19.3 0.0 0.0016 17.1 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1_2 PF13603.1 AJZ75104.1 - 0.0031 16.8 0.2 0.0069 15.7 0.1 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 zinc_ribbon_2 PF13240.1 AJZ75104.1 - 0.042 13.3 0.5 8.5 6.0 0.0 2.8 2 0 0 2 2 2 0 zinc-ribbon domain GARS_A PF01071.14 AJZ75105.1 - 1.2e-76 256.6 0.1 1.6e-76 256.2 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 AJZ75105.1 - 2.7e-31 108.0 0.0 6.6e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 AJZ75105.1 - 1.1e-30 105.6 0.0 2e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 AJZ75105.1 - 5.3e-11 42.5 0.0 1.4e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 AJZ75105.1 - 1.2e-07 31.7 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AJZ75105.1 - 1.4e-07 31.0 0.0 3.4e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 AJZ75105.1 - 8.1e-07 28.0 0.0 9.3e-05 21.3 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AJZ75105.1 - 8.9e-07 28.4 0.0 1.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AJZ75105.1 - 3.8e-05 23.1 0.0 6.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 AJZ75105.1 - 8.1e-05 22.1 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 AJZ75105.1 - 0.00014 21.3 0.0 0.00033 20.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 AJZ75105.1 - 0.0034 16.6 0.0 0.0061 15.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain 5-FTHF_cyc-lig PF01812.15 AJZ75106.1 - 1.2e-39 136.0 0.0 1.3e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family THF_DHG_CYH_C PF02882.14 AJZ75107.1 - 8.8e-60 200.4 0.6 1.5e-59 199.6 0.4 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 AJZ75107.1 - 4.7e-40 136.2 0.2 8.3e-40 135.4 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Shikimate_DH PF01488.15 AJZ75107.1 - 0.012 15.7 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Vps16_N PF04841.8 AJZ75107.1 - 0.041 12.4 0.0 0.059 11.8 0.0 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region DUF1884 PF08967.5 AJZ75107.1 - 0.091 12.8 0.0 0.57 10.2 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1884) Semialdhyde_dh PF01118.19 AJZ75107.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Trypsin_2 PF13365.1 AJZ75108.1 - 3.3e-21 75.4 0.7 6.5e-21 74.5 0.2 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 AJZ75108.1 - 5.1e-15 55.6 0.1 1e-14 54.6 0.1 1.5 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 AJZ75108.1 - 6.7e-15 54.7 0.4 2e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 AJZ75108.1 - 6.5e-07 29.4 1.0 0.036 14.2 0.0 3.6 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Peptidase_S29 PF02907.10 AJZ75108.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S7 PF00949.16 AJZ75108.1 - 0.013 14.9 0.2 0.05 13.0 0.1 2.0 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 AJZ75108.1 - 0.025 13.0 0.4 0.038 12.4 0.3 1.2 1 0 0 1 1 1 0 Peptidase S46 Cupin_2 PF07883.6 AJZ75109.1 - 7.9e-11 41.3 0.0 1.4e-10 40.5 0.0 1.4 2 0 0 2 2 2 1 Cupin domain CENP-C_C PF11699.3 AJZ75109.1 - 2.1e-05 24.4 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.14 AJZ75109.1 - 0.0012 18.5 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.9 AJZ75109.1 - 0.079 12.9 0.1 0.13 12.2 0.0 1.5 2 0 0 2 2 2 0 ARD/ARD' family Cupin_1 PF00190.17 AJZ75109.1 - 0.084 12.3 0.0 0.12 11.8 0.0 1.3 1 1 0 1 1 1 0 Cupin Formyl_trans_N PF00551.14 AJZ75110.1 - 5.4e-50 169.4 0.0 6.2e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase HAD PF12710.2 AJZ75110.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.5 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Vps51 PF08700.6 AJZ75112.1 - 0.0015 18.3 0.8 0.0075 16.0 0.6 1.9 1 1 0 1 1 1 1 Vps51/Vps67 SCP-1 PF05483.7 AJZ75112.1 - 0.045 11.5 0.2 0.047 11.4 0.2 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) PSDC PF12588.3 AJZ75112.1 - 0.14 11.7 0.2 0.16 11.6 0.1 1.1 1 0 0 1 1 1 0 Phophatidylserine decarboxylase Response_reg PF00072.19 AJZ75113.1 - 1.8e-17 63.3 0.1 2.1e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain 2-Hacid_dh_C PF02826.14 AJZ75113.1 - 0.02 14.0 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain B12-binding PF02310.14 AJZ75113.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 B12 binding domain ArsR PF09824.4 AJZ75114.1 - 0.013 14.8 0.0 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 ArsR transcriptional regulator HTH_20 PF12840.2 AJZ75114.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_21 PF05050.7 AJZ75115.1 - 2.7e-21 76.2 0.0 3.7e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.6 AJZ75115.1 - 1.1e-05 24.6 0.3 1.6e-05 24.1 0.2 1.1 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein DUF3240 PF11582.3 AJZ75115.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) DUF2454 PF10521.4 AJZ75116.1 - 0.024 13.6 0.1 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) YCII PF03795.9 AJZ75116.1 - 0.028 14.6 0.0 0.037 14.2 0.0 1.1 1 0 0 1 1 1 0 YCII-related domain VHS PF00790.14 AJZ75116.1 - 0.096 12.3 0.2 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 VHS domain Methyltransf_14 PF08484.6 AJZ75117.1 - 0.041 13.4 0.8 0.056 12.9 0.3 1.4 1 1 1 2 2 2 0 C-methyltransferase C-terminal domain zf-CpG_bind_C PF12269.3 AJZ75117.1 - 0.045 13.2 0.7 0.047 13.1 0.5 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DUF3502 PF12010.3 AJZ75117.1 - 0.055 13.4 0.1 0.062 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) DUF2968 PF11180.3 AJZ75117.1 - 0.063 12.6 1.5 0.077 12.3 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Hamartin PF04388.7 AJZ75117.1 - 0.071 11.7 0.6 0.074 11.7 0.4 1.0 1 0 0 1 1 1 0 Hamartin protein Phage_GP20 PF06810.6 AJZ75117.1 - 0.092 12.1 4.6 0.11 11.9 3.2 1.3 1 1 0 1 1 1 0 Phage minor structural protein GP20 Mnd1 PF03962.10 AJZ75117.1 - 0.75 9.4 5.6 0.83 9.2 3.9 1.0 1 0 0 1 1 1 0 Mnd1 family zf-DHHC PF01529.15 AJZ75118.1 - 6.3 6.1 5.3 13 5.1 3.7 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase A2M_N PF01835.14 AJZ75119.1 - 0.0012 19.0 0.0 0.0012 19.0 0.0 3.5 1 1 3 4 4 4 1 MG2 domain CarboxypepD_reg PF13620.1 AJZ75119.1 - 0.019 15.0 4.7 0.21 11.6 0.1 3.4 2 1 1 3 3 3 0 Carboxypeptidase regulatory-like domain DUF4320 PF14208.1 AJZ75119.1 - 0.17 11.8 6.6 0.081 12.8 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) Bap31 PF05529.7 AJZ75120.1 - 0.49 9.8 1.9 0.69 9.3 1.3 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Hemerythrin PF01814.18 AJZ75121.1 - 1.5e-12 47.8 0.4 3.2e-10 40.2 0.0 2.2 1 1 0 2 2 2 2 Hemerythrin HHE cation binding domain FAA_hydrolase PF01557.13 AJZ75121.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family DUF4473 PF14747.1 AJZ75121.1 - 0.19 12.0 1.0 3.6 7.8 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4473) Copper-bind PF00127.15 AJZ75122.1 - 5.2e-07 29.8 1.6 8.4e-07 29.1 0.1 2.1 2 1 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJZ75122.1 - 7e-05 22.6 0.0 0.00024 20.9 0.0 1.8 1 1 0 1 1 1 1 Cupredoxin-like domain Daxx PF03344.10 AJZ75122.1 - 0.17 10.3 9.3 0.19 10.1 6.4 1.0 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 AJZ75122.1 - 2.6 6.9 9.2 3.9 6.3 6.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2890 PF11081.3 AJZ75122.1 - 4.8 7.1 16.5 6.5 6.7 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nit_Regul_Hom PF10126.4 AJZ75124.1 - 0.011 15.5 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII Clc-like PF07062.7 AJZ75124.1 - 0.03 13.5 0.4 0.033 13.4 0.3 1.1 1 0 0 1 1 1 0 Clc-like AsnC_trans_reg PF01037.16 AJZ75125.1 - 0.00017 21.2 0.1 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 AsnC family YyzF PF14116.1 AJZ75125.1 - 0.18 11.8 0.8 0.3 11.0 0.5 1.4 1 0 0 1 1 1 0 YyzF-like protein UvrC_HhH_N PF08459.6 AJZ75126.1 - 3e-48 163.2 0.1 1e-47 161.5 0.0 1.9 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.19 AJZ75126.1 - 3e-12 46.7 6.0 3.4e-12 46.5 1.5 2.5 2 0 0 2 2 2 1 GIY-YIG catalytic domain UVR PF02151.14 AJZ75126.1 - 5e-08 32.2 0.1 1.5e-07 30.6 0.1 1.9 1 0 0 1 1 1 1 UvrB/uvrC motif ABC_tran PF00005.22 AJZ75127.1 - 6.2e-25 88.0 1.1 5.2e-10 39.7 0.1 4.9 4 1 0 4 4 4 3 ABC transporter SMC_N PF02463.14 AJZ75127.1 - 9.3e-11 41.3 0.5 0.012 14.8 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AJZ75127.1 - 1.4e-08 35.1 7.9 0.0012 18.8 0.1 4.1 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 AJZ75127.1 - 5.8e-08 32.1 0.3 0.013 14.9 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_14 PF13173.1 AJZ75127.1 - 7.5e-08 32.3 0.1 0.071 13.0 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 AJZ75127.1 - 6e-07 29.6 0.0 0.0045 16.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 AJZ75127.1 - 1.4e-06 28.1 0.1 0.091 12.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 AJZ75127.1 - 3.6e-06 26.2 0.2 0.029 13.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 AJZ75127.1 - 3.9e-06 27.1 0.0 0.054 13.8 0.0 3.2 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 AJZ75127.1 - 4.6e-06 25.7 0.3 1.7 7.4 0.0 4.2 4 0 0 4 4 4 2 NB-ARC domain AAA_10 PF12846.2 AJZ75127.1 - 4.9e-06 26.2 0.3 0.039 13.3 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 AJZ75127.1 - 1.4e-05 25.2 5.0 0.14 12.3 0.0 4.6 4 1 0 4 4 4 2 AAA domain AAA_25 PF13481.1 AJZ75127.1 - 2.5e-05 23.7 0.1 0.17 11.2 0.0 3.1 4 0 0 4 4 2 2 AAA domain DnaJ_CXXCXGXG PF00684.14 AJZ75127.1 - 3.4e-05 23.7 7.7 0.0043 17.0 0.3 4.0 3 1 1 4 4 4 1 DnaJ central domain AAA_17 PF13207.1 AJZ75127.1 - 6.8e-05 23.6 9.6 0.066 14.0 0.0 4.4 6 1 0 6 6 3 2 AAA domain NACHT PF05729.7 AJZ75127.1 - 0.00016 21.3 0.0 0.095 12.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.1 AJZ75127.1 - 0.00022 21.6 11.0 0.00047 20.5 0.2 3.4 4 0 0 4 4 3 1 AAA domain T2SE PF00437.15 AJZ75127.1 - 0.00023 20.1 0.2 0.47 9.3 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein KaiC PF06745.8 AJZ75127.1 - 0.00033 19.8 0.0 0.81 8.7 0.0 2.5 2 0 0 2 2 2 2 KaiC FtsK_SpoIIIE PF01580.13 AJZ75127.1 - 0.00039 19.9 0.2 0.41 10.0 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_19 PF13245.1 AJZ75127.1 - 0.00051 19.7 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain APS_kinase PF01583.15 AJZ75127.1 - 0.00062 19.4 0.7 1.2 8.7 0.0 2.8 3 0 0 3 3 2 2 Adenylylsulphate kinase Viral_helicase1 PF01443.13 AJZ75127.1 - 0.001 18.6 0.0 0.16 11.5 0.0 2.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.18 AJZ75127.1 - 0.0019 18.1 3.4 0.13 12.2 0.0 3.6 3 1 0 3 3 3 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 AJZ75127.1 - 0.0024 17.6 1.2 1.2 8.8 0.0 3.0 3 0 0 3 3 2 1 Archaeal ATPase MobB PF03205.9 AJZ75127.1 - 0.0028 17.3 0.4 0.33 10.6 0.1 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 AJZ75127.1 - 0.0028 16.6 0.1 1.4 7.8 0.0 2.6 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 AJZ75127.1 - 0.0047 16.6 0.3 0.72 9.5 0.0 3.4 3 0 0 3 3 3 1 NTPase cobW PF02492.14 AJZ75127.1 - 0.0059 16.0 1.4 0.51 9.7 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 AJZ75127.1 - 0.0068 15.2 0.1 0.16 10.6 0.1 2.4 2 0 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 AJZ75127.1 - 0.0068 16.5 0.0 1.9 8.6 0.0 3.0 2 0 0 2 2 2 1 RNA helicase BCA_ABC_TP_C PF12399.3 AJZ75127.1 - 0.029 14.0 0.2 0.2 11.3 0.0 2.5 3 0 0 3 3 2 0 Branched-chain amino acid ATP-binding cassette transporter Miro PF08477.8 AJZ75127.1 - 0.047 14.1 0.3 15 6.0 0.1 3.2 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 AJZ75127.1 - 0.059 12.4 0.0 2.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 AJZ75127.1 - 0.06 12.9 0.0 16 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 AJZ75127.1 - 0.077 12.1 0.0 12 5.0 0.0 2.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_28 PF13521.1 AJZ75127.1 - 0.082 12.8 0.1 17 5.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain RNA12 PF10443.4 AJZ75127.1 - 0.091 11.2 0.0 6.1 5.2 0.0 2.2 2 0 0 2 2 2 0 RNA12 protein UPF0079 PF02367.12 AJZ75127.1 - 0.093 12.3 0.1 16 5.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 AJZ75127.1 - 0.094 12.6 3.8 12 5.9 0.0 4.2 4 2 0 4 4 3 0 Putative exonuclease SbcCD, C subunit DAP3 PF10236.4 AJZ75127.1 - 0.11 11.3 0.1 9.4 5.0 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 E6 PF00518.12 AJZ75127.1 - 0.19 12.0 2.7 0.44 10.8 0.0 2.9 3 0 0 3 3 2 0 Early Protein (E6) UvrB PF12344.3 AJZ75128.1 - 1.1e-20 72.8 1.8 1.1e-20 72.8 1.2 2.4 2 0 0 2 2 2 1 Ultra-violet resistance protein B Helicase_C PF00271.26 AJZ75128.1 - 1.3e-15 56.9 0.1 6.4e-15 54.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AJZ75128.1 - 2.5e-10 40.4 5.3 3.7e-10 39.9 0.2 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UVR PF02151.14 AJZ75128.1 - 6.1e-07 28.7 4.7 4.1e-06 26.1 3.3 2.6 1 0 0 1 1 1 1 UvrB/uvrC motif DEAD PF00270.24 AJZ75128.1 - 1.9e-06 27.4 0.6 0.00011 21.6 0.1 3.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.1 AJZ75128.1 - 1.7e-05 24.4 0.1 0.0013 18.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 AJZ75128.1 - 0.0038 16.8 0.1 0.19 11.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain Met_synt_B12 PF02965.12 AJZ75128.1 - 0.018 14.2 0.2 0.04 13.0 0.1 1.5 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain UB2H PF14814.1 AJZ75128.1 - 0.047 13.4 0.0 0.18 11.5 0.0 2.1 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain AAA_33 PF13671.1 AJZ75128.1 - 0.065 13.1 0.0 0.37 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Methyltransf_25 PF13649.1 AJZ75128.1 - 0.1 13.0 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain UvrD-helicase PF00580.16 AJZ75128.1 - 4.1 6.6 14.0 11 5.2 1.0 3.1 2 2 0 2 2 2 0 UvrD/REP helicase N-terminal domain Pyridox_ox_2 PF12900.2 AJZ75130.1 - 4.4e-21 75.2 0.0 6.2e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 AJZ75130.1 - 2e-14 53.3 0.0 3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.7 AJZ75130.1 - 0.063 12.7 0.0 0.097 12.1 0.0 1.3 1 1 0 1 1 1 0 Putative FMN-binding domain BNR PF02012.15 AJZ75131.1 - 2.8e-11 41.4 16.5 0.016 14.8 0.3 5.8 5 0 0 5 5 5 5 BNR/Asp-box repeat PSII_BNR PF14870.1 AJZ75131.1 - 3.6e-09 36.0 1.4 1.1e-05 24.5 0.3 3.3 1 1 1 3 3 3 3 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.1 AJZ75131.1 - 6.8e-05 22.2 0.6 0.0007 18.9 0.4 2.4 1 1 0 1 1 1 1 BNR repeat-like domain DUF4185 PF13810.1 AJZ75131.1 - 0.00078 18.4 3.1 0.82 8.5 0.0 3.7 2 2 3 5 5 5 2 Domain of unknown function (DUF4185) SBBP PF06739.6 AJZ75131.1 - 0.0021 17.7 0.8 0.0087 15.8 0.1 2.4 2 0 0 2 2 2 1 Beta-propeller repeat Reg_prop PF07494.6 AJZ75131.1 - 0.0084 16.0 0.1 17 5.8 0.0 3.7 4 0 0 4 4 4 2 Two component regulator propeller End_beta_propel PF12217.3 AJZ75131.1 - 0.016 13.9 0.1 1.9 7.0 0.0 3.1 1 1 1 3 3 3 0 Catalytic beta propeller domain of bacteriophage endosialidase YtkA PF13115.1 AJZ75132.1 - 1.5e-10 41.2 0.3 2.1e-10 40.7 0.2 1.2 1 0 0 1 1 1 1 YtkA-like Big_1 PF02369.11 AJZ75132.1 - 0.00063 19.6 0.1 0.00075 19.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) Filamin PF00630.14 AJZ75132.1 - 0.036 14.6 0.0 0.044 14.3 0.0 1.2 1 0 0 1 1 1 0 Filamin/ABP280 repeat DUF824 PF05688.6 AJZ75132.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) DUF3185 PF11381.3 AJZ75133.1 - 2.8 7.7 0.0 2.8 7.7 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3185) RusA PF05866.6 AJZ75134.1 - 0.0015 18.8 0.2 0.002 18.5 0.2 1.2 1 0 0 1 1 1 1 Endodeoxyribonuclease RusA Borrelia_REV PF03978.8 AJZ75134.1 - 0.02 14.6 0.6 0.025 14.2 0.4 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein DUF2508 PF10704.4 AJZ75134.1 - 0.42 10.8 2.8 0.98 9.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Bac_luciferase PF00296.15 AJZ75135.1 - 1.2e-57 195.3 0.0 1.5e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Fe-ADH PF00465.14 AJZ75136.1 - 4.1e-50 170.4 0.0 1.2e-49 168.8 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 AJZ75136.1 - 2.8e-17 62.8 0.0 4.8e-17 62.0 0.0 1.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 AJZ75136.1 - 7.8e-05 21.7 0.0 0.019 13.8 0.0 2.2 2 0 0 2 2 2 2 3-dehydroquinate synthase Citrate_synt PF00285.16 AJZ75139.1 - 2.5e-136 454.1 0.1 2.8e-136 453.9 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase DHHA1 PF02272.14 AJZ75141.1 - 3.1e-11 42.8 2.2 3.7e-11 42.5 0.4 2.0 2 0 0 2 2 2 1 DHHA1 domain DHH PF01368.15 AJZ75141.1 - 0.0045 16.6 3.2 0.021 14.4 1.1 2.5 2 1 0 2 2 2 1 DHH family DFP PF04127.10 AJZ75141.1 - 0.06 12.9 0.6 0.22 11.0 0.1 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein YjgF_endoribonc PF14588.1 AJZ75142.1 - 4.5e-37 127.2 0.0 5.1e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 AJZ75142.1 - 1.7e-19 69.7 0.0 2.1e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP BON PF04972.12 AJZ75142.1 - 0.082 12.6 0.0 0.47 10.2 0.0 2.3 2 1 1 3 3 3 0 BON domain TM_helix PF05552.7 AJZ75143.1 - 4.5e-11 42.2 9.9 4.7e-08 32.5 2.0 3.2 4 0 0 4 4 4 2 Conserved TM helix MS_channel PF00924.13 AJZ75143.1 - 1.1e-08 34.7 5.3 1.1e-08 34.7 3.7 2.4 3 1 0 3 3 3 1 Mechanosensitive ion channel SseC PF04888.7 AJZ75143.1 - 0.0027 17.1 1.3 0.0027 17.1 0.9 2.2 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family Colicin_V PF02674.11 AJZ75143.1 - 0.062 13.1 21.6 0.23 11.3 5.3 3.1 2 1 1 3 3 3 0 Colicin V production protein DUF502 PF04367.8 AJZ75143.1 - 0.062 13.0 2.8 4.7 7.0 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF502) DUF1043 PF06295.7 AJZ75143.1 - 0.21 11.2 2.4 3.5 7.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) FA_desaturase PF00487.19 AJZ75143.1 - 1.2 8.4 7.9 0.43 9.9 3.4 1.9 1 1 0 1 1 1 0 Fatty acid desaturase FtsX PF02687.16 AJZ75143.1 - 1.8 8.3 27.4 0.33 10.7 0.3 3.5 3 1 1 4 4 4 0 FtsX-like permease family TrmB PF01978.14 AJZ75144.1 - 2.8e-14 52.5 0.2 7.8e-14 51.1 0.1 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 AJZ75144.1 - 0.012 14.5 0.1 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB OstA PF03968.9 AJZ75144.1 - 0.09 12.7 0.1 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 OstA-like protein DUF4351 PF14261.1 AJZ75146.1 - 0.004 17.0 1.5 0.0043 16.8 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4351) ASL_C PF08328.6 AJZ75146.1 - 0.0067 16.2 0.4 0.0089 15.8 0.3 1.3 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal AAA_14 PF13173.1 AJZ75146.1 - 0.073 12.9 0.4 0.099 12.5 0.3 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 AJZ75147.1 - 8.8e-37 126.2 0.0 1.6e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 AJZ75147.1 - 6.3e-09 35.5 1.4 6.3e-09 35.5 1.0 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_2 PF07724.9 AJZ75147.1 - 2.2e-08 34.1 0.0 7.1e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 AJZ75147.1 - 4.5e-06 26.5 0.0 1.9e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AJZ75147.1 - 1.1e-05 24.6 0.0 3.7e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AJZ75147.1 - 2.3e-05 24.4 0.0 0.0018 18.2 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AJZ75147.1 - 3.2e-05 24.0 0.0 0.00028 21.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AJZ75147.1 - 0.00017 20.7 0.0 0.00035 19.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 AJZ75147.1 - 0.00036 21.3 0.3 0.0013 19.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain Vps4_C PF09336.5 AJZ75147.1 - 0.00052 19.8 0.2 0.0023 17.7 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.1 AJZ75147.1 - 0.00059 19.2 0.2 0.014 14.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 AJZ75147.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AJZ75147.1 - 0.0019 17.9 0.0 0.022 14.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 AJZ75147.1 - 0.0025 16.8 0.0 0.1 11.5 0.0 2.3 1 1 1 2 2 2 1 KAP family P-loop domain Arch_ATPase PF01637.13 AJZ75147.1 - 0.0027 17.4 1.2 0.28 10.8 0.0 2.7 2 1 1 3 3 2 1 Archaeal ATPase ResIII PF04851.10 AJZ75147.1 - 0.004 17.0 0.0 0.0087 15.9 0.0 1.6 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit TIP49 PF06068.8 AJZ75147.1 - 0.0078 14.9 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_28 PF13521.1 AJZ75147.1 - 0.0095 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AJZ75147.1 - 0.011 15.8 0.0 0.043 13.9 0.0 2.2 1 1 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 AJZ75147.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 AJZ75147.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 AJZ75147.1 - 0.013 15.7 0.1 0.044 14.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 AJZ75147.1 - 0.017 14.8 0.1 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 AJZ75147.1 - 0.022 14.2 0.0 0.074 12.5 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 AJZ75147.1 - 0.028 13.5 0.2 2.2 7.3 0.0 2.8 2 1 1 3 3 3 0 KaiC Mg_chelatase PF01078.16 AJZ75147.1 - 0.031 13.4 0.0 0.068 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 AJZ75147.1 - 0.039 13.4 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TPR_11 PF13414.1 AJZ75147.1 - 0.042 13.4 0.5 0.11 12.2 0.3 1.7 1 1 0 1 1 1 0 TPR repeat NACHT PF05729.7 AJZ75147.1 - 0.068 12.8 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 AJZ75147.1 - 0.072 12.5 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 AJZ75147.1 - 0.08 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.1 AJZ75147.1 - 0.15 11.6 0.0 2 7.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain Peptidase_M10 PF00413.19 AJZ75148.1 - 6.5e-11 42.1 0.8 1.4e-10 41.1 0.6 1.6 1 1 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.1 AJZ75148.1 - 0.00012 22.1 0.3 0.00017 21.6 0.2 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 AJZ75148.1 - 0.00037 20.4 0.2 0.00061 19.7 0.0 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 AJZ75148.1 - 0.0025 17.2 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 AJZ75148.1 - 0.051 13.0 0.2 0.1 12.1 0.1 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 AJZ75148.1 - 0.051 14.0 0.3 0.13 12.7 0.2 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 AJZ75148.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF3152 PF11350.3 AJZ75148.1 - 0.11 12.0 0.2 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) GIY-YIG PF01541.19 AJZ75149.1 - 4.5e-07 30.1 0.4 5.7e-07 29.8 0.3 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain Ribosomal_L18_c PF14204.1 AJZ75149.1 - 0.0025 18.3 0.4 0.0034 17.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region GH97_C PF14509.1 AJZ75149.1 - 0.059 13.4 0.0 0.072 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation RNA_pol_Rpb5_C PF01191.14 AJZ75149.1 - 0.073 12.6 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain CPSase_sm_chain PF00988.17 AJZ75151.1 - 1.1e-49 167.2 0.0 2.4e-49 166.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 AJZ75151.1 - 1.6e-43 148.3 0.0 2.6e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AJZ75151.1 - 4.8e-08 32.7 0.2 3e-06 26.8 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 AsnC_trans_reg PF01037.16 AJZ75152.1 - 2.1e-07 30.5 0.1 2.3e-07 30.4 0.1 1.0 1 0 0 1 1 1 1 AsnC family YkyA PF10368.4 AJZ75152.1 - 0.013 14.8 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein PMBR PF09373.5 AJZ75153.1 - 0.067 13.1 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Pseudomurein-binding repeat HTH_45 PF14947.1 AJZ75155.1 - 4.9e-10 39.0 1.8 8e-10 38.4 1.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix PHO4 PF01384.15 AJZ75156.1 - 0.0006 18.5 6.8 0.00068 18.3 4.7 1.2 1 0 0 1 1 1 1 Phosphate transporter family PetM PF08041.6 AJZ75156.1 - 0.57 9.7 6.8 3.9 7.0 0.0 4.1 4 0 0 4 4 4 0 PetM family of cytochrome b6f complex subunit 7 Ycf4 PF02392.11 AJZ75156.1 - 7 5.9 13.6 0.029 13.6 1.4 2.6 1 1 3 4 4 4 0 Ycf4 Copper-bind PF00127.15 AJZ75157.1 - 5e-06 26.6 0.2 2e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJZ75157.1 - 5.3e-05 23.0 0.0 0.00018 21.3 0.0 1.9 2 0 0 2 2 2 1 Cupredoxin-like domain Big_1 PF02369.11 AJZ75157.1 - 0.0038 17.1 4.0 0.02 14.7 1.0 2.5 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) DUF824 PF05688.6 AJZ75157.1 - 0.061 12.9 0.3 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) Big_3_4 PF13754.1 AJZ75157.1 - 8 6.8 10.7 0.18 12.1 1.0 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DUF365 PF04033.7 AJZ75158.1 - 0.029 14.3 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF365) TFIIB PF00382.14 AJZ75159.1 - 2.5e-35 120.1 3.9 3.8e-18 65.0 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJZ75159.1 - 2.9e-06 26.5 1.1 4.9e-06 25.7 0.8 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 AJZ75159.1 - 0.00023 20.7 0.5 0.003 17.1 0.1 2.1 1 1 0 2 2 2 1 Cyclin, N-terminal domain HTH_AsnC-type PF13404.1 AJZ75159.1 - 0.00042 19.8 0.0 0.034 13.6 0.0 2.6 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.7 AJZ75159.1 - 0.005 16.4 0.2 0.08 12.5 0.0 2.6 3 0 0 3 3 3 1 HTH domain A2L_zn_ribbon PF08792.5 AJZ75159.1 - 0.026 13.9 0.6 0.046 13.1 0.4 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain HTH_Crp_2 PF13545.1 AJZ75159.1 - 0.062 13.0 0.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain zf-ribbon_3 PF13248.1 AJZ75159.1 - 0.064 12.4 0.7 0.14 11.4 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain HTH_24 PF13412.1 AJZ75159.1 - 0.065 12.6 0.0 1.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding OrfB_Zn_ribbon PF07282.6 AJZ75159.1 - 0.28 10.8 2.4 0.25 11.0 0.3 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF1059 PF06348.6 AJZ75161.1 - 3.6e-08 33.1 0.6 7.9e-08 32.0 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1059) UBA_3 PF09288.5 AJZ75162.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain MtlR PF05068.7 AJZ75162.1 - 0.059 12.7 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Mannitol repressor GXWXG PF14231.1 AJZ75162.1 - 0.073 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 GXWXG protein ATP-synt_F PF01990.12 AJZ75163.1 - 6.6e-16 58.4 0.0 7.3e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Trp_syntA PF00290.15 AJZ75163.1 - 0.017 13.6 0.0 0.017 13.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain DUF4469 PF14734.1 AJZ75163.1 - 0.032 14.0 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold YqhR PF11085.3 AJZ75164.1 - 0.0044 16.5 4.2 0.0053 16.3 2.9 1.4 1 1 0 1 1 1 1 Conserved membrane protein YqhR DUF1761 PF08570.5 AJZ75164.1 - 0.048 13.6 5.6 0.073 13.0 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) DUF2938 PF11158.3 AJZ75164.1 - 0.54 9.5 10.3 13 5.0 7.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2938) SPC12 PF06645.8 AJZ75164.1 - 0.7 9.7 0.0 0.7 9.7 0.0 2.5 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) ABC2_membrane_3 PF12698.2 AJZ75164.1 - 1.1 8.2 10.0 1.3 8.0 7.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Fic PF02661.13 AJZ75165.1 - 9.2e-24 83.9 0.0 1.9e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family ADH_N PF08240.7 AJZ75166.1 - 1.6e-23 82.5 2.3 3.2e-23 81.5 1.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AJZ75166.1 - 2.5e-20 72.3 0.0 4.5e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AJZ75166.1 - 5.3e-06 27.3 0.1 9.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SnoaL_3 PF13474.1 AJZ75167.1 - 1.3e-07 31.6 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.5 AJZ75167.1 - 0.00024 20.9 0.0 0.00055 19.8 0.0 1.6 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association DUF4440 PF14534.1 AJZ75167.1 - 0.0034 17.5 0.0 0.0047 17.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) TPP_enzyme_N PF02776.13 AJZ75169.1 - 1.9e-60 203.2 0.0 1.7e-59 200.1 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 AJZ75169.1 - 2.5e-44 150.3 0.0 5.9e-44 149.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 AJZ75169.1 - 5.8e-44 149.3 0.8 1.3e-43 148.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HMGL-like PF00682.14 AJZ75170.1 - 2.7e-75 253.0 1.2 4.4e-75 252.3 0.8 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 AJZ75170.1 - 1e-25 90.0 1.3 2e-25 89.1 0.9 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Glyco_hydro_97 PF10566.4 AJZ75170.1 - 0.028 13.5 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase 97 UPF0154 PF03672.8 AJZ75170.1 - 0.053 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Iso_dh PF00180.15 AJZ75171.1 - 7.4e-103 344.1 0.2 9.3e-103 343.8 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 AJZ75171.1 - 0.00085 18.6 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA DUF4271 PF14093.1 AJZ75172.1 - 0.0064 16.1 4.2 0.0067 16.1 2.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) Mem_trans PF03547.13 AJZ75172.1 - 0.15 10.3 5.1 0.052 11.8 1.7 1.4 1 1 0 1 1 1 0 Membrane transport protein DUF996 PF06195.8 AJZ75172.1 - 0.6 10.0 5.5 1.2 9.1 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF996) AAA_21 PF13304.1 AJZ75174.1 - 6.9e-19 68.8 30.1 1.7e-18 67.6 15.8 3.0 2 2 0 2 2 2 1 AAA domain SMC_N PF02463.14 AJZ75174.1 - 1.3e-06 27.7 2.2 0.0021 17.3 0.6 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 AJZ75174.1 - 2.5e-06 26.8 18.4 2.5e-06 26.8 12.7 3.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 AJZ75174.1 - 0.0085 15.5 0.1 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 AJZ75174.1 - 7.4 6.8 22.8 4.2e+02 1.1 15.8 3.0 1 1 0 1 1 1 0 AAA domain HTH_29 PF13551.1 AJZ75176.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.1 AJZ75176.1 - 0.088 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain zf-ribbon_3 PF13248.1 AJZ75177.1 - 0.027 13.6 0.1 0.027 13.6 0.1 1.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 AJZ75177.1 - 4.6 7.7 7.3 19 5.7 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain DUF4201 PF13870.1 AJZ75179.1 - 0.044 13.2 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF1250 PF06855.7 AJZ75179.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1250) YicC_N PF03755.8 AJZ75179.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 YicC-like family, N-terminal region tRNA-synt_2 PF00152.15 AJZ75180.1 - 5.6e-89 298.2 0.0 1e-88 297.3 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AJZ75180.1 - 8.3e-10 38.3 0.6 1.5e-09 37.5 0.4 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AJZ75180.1 - 0.0082 15.3 0.5 0.29 10.2 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) KH_5 PF13184.1 AJZ75181.1 - 1.4e-05 24.7 0.1 4.1e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 NusA-like KH domain ABC_tran PF00005.22 AJZ75182.1 - 1.2e-26 93.6 0.1 1.8e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.7 AJZ75182.1 - 1.1e-19 70.5 0.2 1.9e-19 69.7 0.1 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.1 AJZ75182.1 - 3.4e-11 43.6 1.6 4.1e-10 40.1 0.2 2.1 1 1 1 2 2 2 1 AAA domain SMC_N PF02463.14 AJZ75182.1 - 0.0017 17.5 0.3 0.0017 17.5 0.2 1.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 AJZ75182.1 - 0.0094 15.4 0.3 0.88 8.9 0.0 2.3 1 1 0 2 2 2 2 AAA-like domain BsuBI_PstI_RE PF06616.6 AJZ75182.1 - 0.05 12.3 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus SNARE_assoc PF09335.6 AJZ75184.1 - 1.7e-16 60.5 3.0 1.7e-16 60.5 2.1 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein COG7 PF10191.4 AJZ75184.1 - 0.13 10.1 0.0 0.17 9.7 0.0 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Fumarate_red_D PF02313.12 AJZ75184.1 - 0.28 11.0 2.9 0.17 11.8 0.4 1.7 2 0 0 2 2 2 0 Fumarate reductase subunit D DUF2418 PF10332.4 AJZ75184.1 - 0.52 10.6 2.1 1 9.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) DUF1230 PF06799.6 AJZ75184.1 - 0.87 9.4 2.8 2.3 8.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1230) Polysacc_synt_C PF14667.1 AJZ75184.1 - 0.96 9.2 12.2 1 9.1 2.2 2.4 1 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain NfeD PF01957.13 AJZ75184.1 - 1.7 8.7 6.1 6.3 6.9 0.1 2.6 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding zf-DHHC PF01529.15 AJZ75184.1 - 5.3 6.4 6.5 0.41 10.0 1.1 1.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase Pur_DNA_glyco PF02245.11 AJZ75185.1 - 1.1e-60 203.9 0.0 1.2e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) UDG PF03167.14 AJZ75186.1 - 4.5e-38 130.1 0.0 5.4e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Epimerase_2 PF02350.14 AJZ75186.1 - 0.038 12.7 0.0 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase PmbA_TldD PF01523.11 AJZ75187.1 - 6.9e-62 209.3 0.1 8.2e-62 209.1 0.1 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase HATPase_c PF02518.21 AJZ75188.1 - 6.2e-30 103.1 0.0 1.5e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJZ75188.1 - 1.1e-15 57.3 2.4 1.7e-15 56.7 0.1 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 AJZ75188.1 - 1.1e-11 44.6 0.0 1.1e-11 44.6 0.0 2.9 4 0 0 4 4 4 1 HAMP domain PilJ PF13675.1 AJZ75188.1 - 4.8e-08 33.2 0.5 5e-05 23.5 0.0 3.1 3 0 0 3 3 3 2 Type IV pili methyl-accepting chemotaxis transducer N-term HATPase_c_3 PF13589.1 AJZ75188.1 - 2.3e-06 27.2 0.1 7.7e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJZ75188.1 - 0.032 14.0 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Response_reg PF00072.19 AJZ75189.1 - 1.5e-26 92.6 0.3 1.6e-26 92.4 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Lipase_GDSL_3 PF14606.1 AJZ75189.1 - 0.078 12.7 0.1 0.14 11.8 0.1 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CoA_binding_2 PF13380.1 AJZ75189.1 - 0.099 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain Response_reg PF00072.19 AJZ75190.1 - 6e-20 71.3 0.3 1.6e-18 66.7 0.0 2.2 1 1 1 2 2 2 2 Response regulator receiver domain zf-DHHC PF01529.15 AJZ75190.1 - 0.0019 17.6 0.2 0.0019 17.6 0.2 2.2 3 0 0 3 3 3 1 DHHC palmitoyltransferase Tn7_Tnp_TnsA_C PF08721.6 AJZ75190.1 - 0.065 13.2 1.9 1.5 8.8 0.0 3.0 1 1 2 3 3 3 0 TnsA endonuclease C terminal DUF2893 PF11459.3 AJZ75190.1 - 0.11 12.2 0.8 1.5 8.6 0.0 3.0 3 1 0 3 3 3 0 Protein of unknwon function (DUF2893) FYVE_2 PF02318.11 AJZ75190.1 - 0.16 11.8 14.7 0.68 9.8 2.1 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger Zn-ribbon_8 PF09723.5 AJZ75190.1 - 0.19 11.6 22.6 1.6 8.7 0.2 5.3 3 2 2 5 5 5 0 Zinc ribbon domain zinc-ribbons_6 PF07191.7 AJZ75190.1 - 0.2 11.4 16.4 0.11 12.2 2.8 3.3 1 1 2 3 3 3 0 zinc-ribbons Spt4 PF06093.8 AJZ75190.1 - 0.55 10.1 13.4 1.3 8.9 0.5 3.0 1 1 2 3 3 3 0 Spt4/RpoE2 zinc finger DZR PF12773.2 AJZ75190.1 - 0.64 9.8 14.7 2.4 8.0 2.0 2.9 1 1 2 3 3 3 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 AJZ75190.1 - 0.91 9.3 18.8 0.49 10.2 0.6 3.7 3 1 1 4 4 4 0 Transposase zinc-ribbon domain DnaJ_CXXCXGXG PF00684.14 AJZ75190.1 - 1.5 8.9 14.1 4.4 7.4 1.5 2.9 1 1 2 3 3 3 0 DnaJ central domain zf-Mss51 PF13824.1 AJZ75190.1 - 1.6 8.6 9.0 7.1 6.5 1.3 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 TFIIS_C PF01096.13 AJZ75190.1 - 1.7 8.3 15.9 23 4.7 0.2 5.3 5 0 0 5 5 5 0 Transcription factor S-II (TFIIS) zf-Di19 PF05605.7 AJZ75190.1 - 3.3 7.9 12.2 31 4.7 6.8 3.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.1 AJZ75190.1 - 4.8 6.8 16.6 17 5.0 0.0 5.0 4 1 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AJZ75190.1 - 9.1 6.0 16.5 21 4.8 0.0 5.0 4 1 0 4 4 4 0 zinc-ribbon domain T2SE PF00437.15 AJZ75191.1 - 8.5e-13 47.8 0.0 1.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein KH_1 PF00013.24 AJZ75191.1 - 4.7e-08 32.5 3.0 8.7e-08 31.6 0.3 2.7 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 AJZ75191.1 - 5.7e-06 25.8 1.2 1.8e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 KH domain KH_2 PF07650.12 AJZ75191.1 - 6.7e-05 22.3 0.0 0.00022 20.7 0.0 1.9 1 0 0 1 1 1 1 KH domain AAA_22 PF13401.1 AJZ75191.1 - 0.00013 22.0 0.2 0.059 13.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 AJZ75191.1 - 0.00014 22.6 0.0 0.00062 20.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 AJZ75191.1 - 0.00023 21.0 0.1 0.00068 19.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 AJZ75191.1 - 0.00027 21.2 0.1 0.0025 18.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain KH_5 PF13184.1 AJZ75191.1 - 0.00029 20.5 0.4 0.0015 18.2 0.3 2.3 1 0 0 1 1 1 1 NusA-like KH domain PIN_4 PF13638.1 AJZ75191.1 - 0.00032 20.7 0.2 0.00093 19.3 0.1 1.8 1 0 0 1 1 1 1 PIN domain AAA_16 PF13191.1 AJZ75191.1 - 0.00071 19.6 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 AJZ75191.1 - 0.0014 17.8 0.1 0.0037 16.3 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 AJZ75191.1 - 0.0014 18.0 0.0 0.0036 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AJZ75191.1 - 0.0017 18.0 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 AJZ75191.1 - 0.003 17.0 0.0 0.0072 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 AJZ75191.1 - 0.0041 17.4 0.0 0.023 15.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ArgK PF03308.11 AJZ75191.1 - 0.0053 15.5 0.0 0.011 14.5 0.0 1.5 1 0 0 1 1 1 1 ArgK protein NB-ARC PF00931.17 AJZ75191.1 - 0.0065 15.3 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.10 AJZ75191.1 - 0.0073 16.0 0.0 0.042 13.5 0.0 2.4 1 0 0 1 1 1 1 NTPase AAA_29 PF13555.1 AJZ75191.1 - 0.011 15.3 0.1 0.026 14.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 AJZ75191.1 - 0.011 15.3 0.0 0.072 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AJZ75191.1 - 0.023 14.3 0.0 0.058 13.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 AJZ75191.1 - 0.024 14.0 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.24 AJZ75191.1 - 0.032 14.4 0.1 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 AJZ75191.1 - 0.037 14.0 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 AJZ75191.1 - 0.04 13.4 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CbiA PF01656.18 AJZ75191.1 - 0.043 13.2 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RuvB_N PF05496.7 AJZ75191.1 - 0.046 12.7 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 AJZ75191.1 - 0.064 12.2 1.3 0.25 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.5 AJZ75191.1 - 0.065 12.4 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 AJZ75191.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AJZ75191.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Fe_dep_repress PF01325.14 AJZ75192.1 - 3.6e-20 71.6 1.2 6.2e-20 70.9 0.8 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.10 AJZ75192.1 - 1.5e-14 53.4 0.0 3e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain HTH_27 PF13463.1 AJZ75192.1 - 2.3e-06 27.8 0.0 9.1e-06 25.9 0.0 2.0 2 1 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.1 AJZ75192.1 - 4.5e-05 22.7 0.0 9.4e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AJZ75192.1 - 7.7e-05 22.2 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.17 AJZ75192.1 - 0.00012 21.7 0.0 0.00035 20.2 0.0 1.8 1 1 1 2 2 2 1 MarR family TrmB PF01978.14 AJZ75192.1 - 0.00016 21.3 0.1 0.00026 20.6 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.11 AJZ75192.1 - 0.00042 19.8 0.0 0.0012 18.3 0.0 1.8 2 0 0 2 2 1 1 LexA DNA binding domain DUF2250 PF10007.4 AJZ75192.1 - 0.0041 16.9 0.2 0.01 15.7 0.1 1.7 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) DUF4423 PF14394.1 AJZ75192.1 - 0.0043 16.6 0.0 0.012 15.1 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_34 PF13601.1 AJZ75192.1 - 0.0078 16.2 0.1 0.025 14.6 0.0 1.9 1 1 1 2 2 2 1 Winged helix DNA-binding domain HTH_5 PF01022.15 AJZ75192.1 - 0.014 15.0 0.1 0.04 13.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family FeoC PF09012.5 AJZ75192.1 - 0.019 14.6 0.1 0.055 13.1 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_28 PF13518.1 AJZ75192.1 - 0.02 14.8 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_S19e PF01090.14 AJZ75192.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S19e HTH_45 PF14947.1 AJZ75192.1 - 0.023 14.4 1.0 0.036 13.8 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix PAX PF00292.13 AJZ75192.1 - 0.026 14.2 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain HTH_Crp_2 PF13545.1 AJZ75192.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_6 PF01418.12 AJZ75192.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 1 0 Helix-turn-helix domain, rpiR family HTH_12 PF08461.5 AJZ75192.1 - 0.063 13.0 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain Rrf2 PF02082.15 AJZ75192.1 - 0.089 12.9 0.1 0.29 11.2 0.0 1.9 2 1 1 3 3 2 0 Transcriptional regulator TFIIE_alpha PF02002.12 AJZ75192.1 - 0.11 12.0 0.2 0.83 9.1 0.0 2.1 1 1 1 2 2 2 0 TFIIE alpha subunit YjcQ PF09639.5 AJZ75192.1 - 0.13 12.3 0.2 5.1 7.2 0.0 2.7 2 1 0 2 2 2 0 YjcQ protein DUF192 PF02643.10 AJZ75193.1 - 1e-30 105.5 0.0 1.3e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 Na_H_antiport_2 PF13726.1 AJZ75193.1 - 0.056 13.3 0.1 0.086 12.7 0.1 1.3 1 0 0 1 1 1 0 Na+-H+ antiporter family TauE PF01925.14 AJZ75194.1 - 8.6e-53 179.2 31.3 1.1e-52 178.9 21.7 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE 7TM-7TMR_HD PF07698.6 AJZ75194.1 - 0.0049 16.3 27.4 0.13 11.6 2.4 2.2 1 1 1 2 2 2 2 7TM receptor with intracellular HD hydrolase Nepo_coat PF03391.10 AJZ75194.1 - 0.078 12.2 1.5 3.2 6.9 0.1 2.3 2 0 0 2 2 2 0 Nepovirus coat protein, central domain DUF3206 PF11472.3 AJZ75195.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3206) adh_short PF00106.20 AJZ75196.1 - 1.1e-20 74.2 0.0 1.3e-16 60.9 0.0 3.4 3 1 1 4 4 4 2 short chain dehydrogenase adh_short_C2 PF13561.1 AJZ75196.1 - 1e-10 41.7 0.1 3.9e-07 30.1 0.0 3.2 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AJZ75196.1 - 3.7e-08 33.2 0.0 4.7e-07 29.6 0.0 2.6 2 1 1 3 3 3 1 KR domain Epimerase PF01370.16 AJZ75196.1 - 0.0062 16.0 0.0 0.044 13.1 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 7TMR-HDED PF07697.6 AJZ75196.1 - 0.0073 16.0 4.9 0.23 11.1 3.4 2.3 1 1 0 1 1 1 1 7TM-HD extracellular 3HCDH_N PF02737.13 AJZ75196.1 - 0.012 15.2 1.0 0.032 13.8 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CW_binding_2 PF04122.7 AJZ75196.1 - 0.029 14.5 0.0 0.16 12.1 0.0 2.3 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 DUF1904 PF08921.6 AJZ75196.1 - 0.51 10.4 3.2 1.2 9.2 0.2 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1904) tRNA_int_endo PF01974.12 AJZ75199.1 - 1.9e-28 98.0 0.2 3.6e-28 97.1 0.1 1.5 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 AJZ75199.1 - 7e-16 57.5 0.0 1.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain PhoU_div PF01865.11 AJZ75200.1 - 1.3e-17 63.7 11.6 1.6e-17 63.4 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF47 PhoU PF01895.14 AJZ75200.1 - 0.0013 19.1 15.2 0.0039 17.5 1.6 3.2 2 2 1 3 3 3 2 PhoU domain DUF3731 PF12531.3 AJZ75200.1 - 0.0052 16.3 0.6 0.01 15.4 0.4 1.4 1 0 0 1 1 1 1 DNA-K related protein COG5 PF10392.4 AJZ75200.1 - 0.0057 16.6 3.2 1.2 9.1 0.0 2.4 2 0 0 2 2 2 2 Golgi transport complex subunit 5 DUF677 PF05055.7 AJZ75200.1 - 0.011 14.4 1.3 0.011 14.4 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF677) UPF0081 PF03652.10 AJZ75200.1 - 0.03 14.4 1.1 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0081) Laminin_I PF06008.9 AJZ75200.1 - 0.052 12.8 0.4 0.052 12.8 0.3 2.7 1 1 1 2 2 2 0 Laminin Domain I Reo_sigmaC PF04582.7 AJZ75200.1 - 0.079 12.1 1.4 1 8.4 0.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 AJZ75200.1 - 0.12 12.2 8.1 0.17 11.7 0.5 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TerB PF05099.8 AJZ75200.1 - 0.14 11.8 1.8 0.3 10.8 0.1 2.1 2 1 0 2 2 2 0 Tellurite resistance protein TerB DUF4515 PF14988.1 AJZ75200.1 - 0.82 9.2 6.8 5.1 6.7 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4515) FlxA PF14282.1 AJZ75200.1 - 0.87 9.5 6.0 5.2 7.0 0.1 2.8 2 1 0 2 2 2 0 FlxA-like protein DUF1664 PF07889.7 AJZ75200.1 - 0.94 9.2 10.0 0.99 9.2 0.1 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF1836 PF08876.6 AJZ75200.1 - 0.95 9.2 4.2 1 9.1 1.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1836) NPV_P10 PF05531.7 AJZ75200.1 - 1.2 9.4 10.3 0.64 10.3 0.1 3.9 1 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein AHH PF14412.1 AJZ75200.1 - 1.3 9.0 5.5 2.6 8.0 0.2 2.8 2 2 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF3919 PF13057.1 AJZ75200.1 - 2.3 7.6 10.1 0.26 10.7 2.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3919) COG2 PF06148.6 AJZ75200.1 - 4.1 7.2 9.8 1.7 8.5 0.3 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SLS PF14611.1 AJZ75200.1 - 4.3 6.6 8.8 17 4.7 0.3 2.8 1 1 1 2 2 2 0 Mitochondrial inner-membrane-bound regulator Spectrin PF00435.16 AJZ75200.1 - 5.1 7.4 7.8 2 8.7 0.5 2.8 2 2 0 2 2 2 0 Spectrin repeat ORF6C PF10552.4 AJZ75200.1 - 7.1 6.3 8.3 5.3 6.8 0.2 2.9 3 1 0 3 3 2 0 ORF6C domain DASH_Dad4 PF08650.5 AJZ75200.1 - 9.7 6.1 7.4 1.6 8.6 0.8 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad4 DNA_ligase_A_M PF01068.16 AJZ75201.1 - 1.1e-57 194.6 0.4 1.1e-57 194.6 0.2 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AJZ75201.1 - 1.8e-50 171.2 1.4 1.8e-50 171.2 0.9 2.0 3 0 0 3 3 3 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 AJZ75201.1 - 2.8e-22 78.9 0.0 6.7e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 AJZ75201.1 - 0.077 12.6 0.1 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 DNA ligase OB-like domain DUF4117 PF13491.1 AJZ75203.1 - 0.025 14.0 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) NfI_DNAbd_pre-N PF10524.4 AJZ75203.1 - 0.1 12.1 1.1 0.18 11.4 0.7 1.4 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus TcpE PF12648.2 AJZ75203.1 - 0.65 10.1 5.6 0.14 12.2 1.6 1.6 2 0 0 2 2 2 0 TcpE family FBPase_3 PF01950.11 AJZ75204.1 - 3.3e-152 506.6 0.0 3.8e-152 506.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase GTP_EFTU PF00009.22 AJZ75205.1 - 4e-48 163.3 0.0 5.7e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AJZ75205.1 - 1.6e-30 105.1 0.2 6e-30 103.3 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AJZ75205.1 - 1.6e-18 66.5 2.1 4.3e-18 65.2 0.5 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AJZ75205.1 - 2.7e-06 26.9 0.5 5.7e-06 25.8 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 AJZ75205.1 - 0.0039 17.1 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AJZ75205.1 - 0.055 13.9 0.0 0.29 11.6 0.0 2.3 1 1 1 2 2 2 0 Miro-like protein Ferritin_2 PF13668.1 AJZ75205.1 - 0.1 12.5 0.4 0.3 11.0 0.2 1.7 1 1 0 1 1 1 0 Ferritin-like domain Ribosomal_S10 PF00338.17 AJZ75206.1 - 1.7e-26 91.8 0.0 1.9e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DNA_RNApol_7kD PF03604.8 AJZ75207.1 - 0.0001 21.6 2.1 0.00019 20.8 1.4 1.5 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-C4pol PF14260.1 AJZ75208.1 - 0.0085 16.0 11.0 0.79 9.7 2.8 3.4 1 1 1 3 3 3 1 C4-type zinc-finger of DNA polymerase delta zf-CHY PF05495.7 AJZ75208.1 - 0.0088 16.1 17.8 0.2 11.8 3.4 3.1 2 1 1 3 3 3 2 CHY zinc finger YabP PF07873.6 AJZ75208.1 - 0.062 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 YabP family FYVE PF01363.16 AJZ75208.1 - 0.088 12.7 21.4 0.043 13.7 4.4 3.4 2 2 1 3 3 3 0 FYVE zinc finger GATA PF00320.22 AJZ75208.1 - 1.2 8.4 15.6 0.17 11.2 0.5 4.6 5 0 0 5 5 5 0 GATA zinc finger DZR PF12773.2 AJZ75208.1 - 1.7 8.5 18.8 0.85 9.4 3.5 3.6 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.1 AJZ75208.1 - 6.6 6.5 20.9 1.7 8.4 1.6 4.0 4 0 0 4 4 4 0 zinc-RING finger domain Lysine_decarbox PF03641.9 AJZ75209.1 - 1.3e-05 25.0 0.1 5.3e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Possible lysine decarboxylase DNA_processg_A PF02481.10 AJZ75209.1 - 0.001 18.0 0.1 0.048 12.5 0.0 2.3 2 1 0 2 2 2 2 DNA recombination-mediator protein A DAGK_cat PF00781.19 AJZ75209.1 - 0.13 11.6 1.7 0.59 9.5 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain 3HCDH_N PF02737.13 AJZ75210.1 - 3.9e-68 228.6 0.7 6e-68 228.0 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 AJZ75210.1 - 8.6e-32 109.4 0.0 1.7e-24 86.0 0.0 2.6 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 AJZ75210.1 - 1.4e-08 34.5 0.1 2.5e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 AJZ75210.1 - 2.9e-05 23.9 0.1 5.5e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 AJZ75210.1 - 0.00029 20.2 0.5 0.00062 19.1 0.3 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 AJZ75210.1 - 0.00044 20.6 0.9 0.0014 19.0 0.7 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 AJZ75210.1 - 0.039 13.3 2.7 3.1 7.1 1.9 2.3 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Herpes_BLRF2 PF05812.7 AJZ75210.1 - 0.14 11.9 1.6 0.58 9.9 0.8 2.2 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein Saccharop_dh PF03435.13 AJZ75210.1 - 0.15 11.0 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DnaJ PF00226.26 AJZ75211.1 - 7.4e-16 57.6 1.3 1.4e-15 56.7 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain Fer4_15 PF13459.1 AJZ75211.1 - 8.2e-10 39.1 1.3 1.7e-09 38.0 0.9 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.1 AJZ75211.1 - 1.1e-09 38.5 2.5 2.5e-09 37.3 1.7 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.6 AJZ75211.1 - 0.00047 19.9 3.4 0.0011 18.6 2.4 1.6 1 1 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Caudal_act PF04731.7 AJZ75211.1 - 0.086 13.1 7.0 0.14 12.4 4.4 1.7 1 1 0 1 1 1 0 Caudal like protein activation region Fer4 PF00037.22 AJZ75211.1 - 0.46 10.1 7.2 4.7 6.9 2.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain DUF4548 PF15081.1 AJZ75211.1 - 0.48 9.9 4.4 5.7 6.4 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4548) AsnC_trans_reg PF01037.16 AJZ75213.1 - 2.2e-08 33.6 0.1 2.4e-08 33.5 0.1 1.0 1 0 0 1 1 1 1 AsnC family RimK PF08443.6 AJZ75213.1 - 0.015 14.7 0.2 0.017 14.6 0.1 1.1 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF2129 PF09902.4 AJZ75213.1 - 0.1 12.4 0.8 0.18 11.5 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) Pyr_redox_2 PF07992.9 AJZ75214.1 - 9.1e-20 71.3 0.0 3.7e-19 69.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AJZ75214.1 - 7.7e-06 24.9 2.1 0.0001 21.3 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 AJZ75214.1 - 2.1e-05 24.6 0.8 0.0098 15.9 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AJZ75214.1 - 4.2e-05 22.6 0.2 0.018 13.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 AJZ75214.1 - 0.00011 21.4 0.3 0.00032 19.8 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 AJZ75214.1 - 0.0036 17.6 2.1 0.034 14.5 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AJZ75214.1 - 0.0075 14.7 1.2 0.27 9.6 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 AJZ75214.1 - 0.014 15.4 0.0 0.039 13.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 AJZ75214.1 - 0.016 14.1 0.2 15 4.3 0.0 3.0 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 AJZ75214.1 - 0.017 14.2 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 AJZ75214.1 - 0.076 11.8 2.3 0.095 11.5 0.1 2.2 2 1 1 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 AJZ75214.1 - 0.14 11.2 0.2 0.74 8.8 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AJZ75214.1 - 0.19 11.4 0.2 22 4.7 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Ferritin PF00210.19 AJZ75215.1 - 7.9e-18 64.5 0.0 1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 AJZ75215.1 - 0.00099 19.4 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 Rubrerythrin Abhydrolase_6 PF12697.2 AJZ75216.1 - 2.8e-42 145.1 0.0 3.3e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AJZ75216.1 - 2.1e-26 92.9 0.0 1.2e-25 90.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AJZ75216.1 - 4.3e-20 71.9 0.1 6.9e-20 71.2 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AJZ75216.1 - 6.2e-06 25.9 0.0 2.1e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Ser_hydrolase PF06821.8 AJZ75216.1 - 1.5e-05 24.6 0.0 0.019 14.5 0.0 2.3 2 1 0 2 2 2 2 Serine hydrolase Abhydrolase_2 PF02230.11 AJZ75216.1 - 2.7e-05 23.7 0.0 0.081 12.3 0.0 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Ndr PF03096.9 AJZ75216.1 - 0.00018 20.0 0.0 0.00036 19.1 0.0 1.5 1 1 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.5 AJZ75216.1 - 0.00035 20.4 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.8 AJZ75216.1 - 0.0016 18.0 0.0 0.0049 16.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 AJZ75216.1 - 0.0017 17.8 0.0 0.019 14.4 0.0 2.4 1 1 1 2 2 2 1 Serine hydrolase (FSH1) DUF3530 PF12048.3 AJZ75216.1 - 0.0039 16.2 0.1 0.0064 15.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) DUF676 PF05057.9 AJZ75216.1 - 0.007 15.6 0.1 0.014 14.6 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) UPF0227 PF05728.7 AJZ75216.1 - 0.02 14.5 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.6 AJZ75216.1 - 0.033 13.2 0.0 0.31 10.0 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PAC2 PF09754.4 AJZ75216.1 - 0.081 12.7 0.0 0.35 10.6 0.0 2.0 2 1 0 2 2 2 0 PAC2 family DLH PF01738.13 AJZ75216.1 - 0.1 11.8 0.0 7.5 5.7 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family EF1G PF00647.14 AJZ75216.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain PhaC_N PF07167.8 AJZ75217.1 - 3e-13 49.5 0.1 5.3e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Abhydrolase_1 PF00561.15 AJZ75217.1 - 5.5e-11 42.4 0.0 1.8e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3141 PF11339.3 AJZ75217.1 - 1.8e-08 33.2 0.1 3.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3141) Abhydrolase_6 PF12697.2 AJZ75217.1 - 1.4e-07 31.6 0.0 2.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AJZ75217.1 - 1.8e-05 24.4 0.0 9.1e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 AJZ75217.1 - 0.00019 21.1 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PHB_depo_C PF06850.6 AJZ75217.1 - 0.00039 19.6 0.0 0.0029 16.8 0.0 2.3 1 1 0 1 1 1 1 PHB de-polymerase C-terminus DLH PF01738.13 AJZ75217.1 - 0.0014 17.9 0.0 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family PHA_synth_III_E PF09712.5 AJZ75218.1 - 1.3e-17 64.1 0.1 1.6e-17 63.8 0.1 1.2 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Myb_DNA-bind_5 PF13873.1 AJZ75218.1 - 6.8e-05 22.6 2.9 0.0059 16.4 0.3 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Phasin PF05597.6 AJZ75218.1 - 0.00056 19.6 0.6 0.0086 15.8 0.1 2.1 2 0 0 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF972 PF06156.8 AJZ75218.1 - 0.00078 19.7 0.9 0.12 12.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF972) BMFP PF04380.8 AJZ75218.1 - 0.0015 18.5 0.7 0.019 15.0 0.1 2.4 2 1 0 2 2 2 1 Membrane fusogenic activity Bacillus_HBL PF05791.6 AJZ75218.1 - 0.0018 17.6 5.7 0.0044 16.4 1.0 2.2 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF4631 PF15450.1 AJZ75218.1 - 0.0047 15.2 2.7 0.0094 14.2 1.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4631) Snapin_Pallidin PF14712.1 AJZ75218.1 - 0.0057 16.9 4.0 0.89 9.9 0.3 2.2 2 0 0 2 2 2 2 Snapin/Pallidin TelA PF05816.6 AJZ75218.1 - 0.0058 15.3 0.8 1.1 7.8 0.0 2.1 2 0 0 2 2 2 2 Toxic anion resistance protein (TelA) Lge1 PF11488.3 AJZ75218.1 - 0.015 15.4 0.9 1.7 8.8 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DASH_Spc19 PF08287.6 AJZ75218.1 - 0.026 14.1 0.3 0.051 13.1 0.2 1.5 1 0 0 1 1 1 0 Spc19 ATP-synt_B PF00430.13 AJZ75218.1 - 0.027 14.2 0.3 0.077 12.7 0.0 1.7 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF2408 PF10303.4 AJZ75218.1 - 0.045 13.8 3.7 0.27 11.3 1.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Rota_Capsid_VP6 PF00980.12 AJZ75218.1 - 0.079 11.5 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 TPR_MLP1_2 PF07926.7 AJZ75218.1 - 0.082 12.6 3.1 3.5 7.3 0.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mhr1 PF12829.2 AJZ75218.1 - 0.11 12.3 0.4 0.61 9.9 0.1 2.2 1 1 1 2 2 2 0 Transcriptional regulation of mitochondrial recombination DivIC PF04977.10 AJZ75218.1 - 0.11 11.9 3.2 0.37 10.3 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator PilJ PF13675.1 AJZ75218.1 - 0.12 12.6 0.2 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Baculo_PEP_C PF04513.7 AJZ75218.1 - 0.12 12.1 0.0 0.83 9.4 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2130 PF09903.4 AJZ75218.1 - 0.13 10.9 7.0 0.098 11.3 0.4 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) GP41 PF00517.12 AJZ75218.1 - 0.14 11.7 1.9 4.5 6.7 0.1 2.3 2 0 0 2 2 2 0 Retroviral envelope protein IncA PF04156.9 AJZ75218.1 - 0.2 11.2 0.5 8 6.0 0.0 2.1 2 0 0 2 2 2 0 IncA protein DUF2730 PF10805.3 AJZ75218.1 - 0.27 10.9 2.9 0.58 9.9 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Phlebovirus_NSM PF07246.6 AJZ75218.1 - 0.28 10.3 2.0 0.58 9.2 0.1 1.9 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M MutS_IV PF05190.13 AJZ75218.1 - 0.28 11.3 3.0 4.2 7.6 0.8 2.3 2 0 0 2 2 2 0 MutS family domain IV Retrotrans_gag PF03732.12 AJZ75218.1 - 0.3 11.1 2.4 1.3 9.1 0.2 2.6 1 1 1 2 2 2 0 Retrotransposon gag protein BBS2_C PF14782.1 AJZ75218.1 - 0.33 9.4 4.5 0.048 12.2 0.4 1.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal Laminin_II PF06009.7 AJZ75218.1 - 0.34 10.6 2.0 1.6 8.4 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II Spc24 PF08286.6 AJZ75218.1 - 0.46 10.2 5.6 1.1 8.9 0.3 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 BLOC1_2 PF10046.4 AJZ75218.1 - 0.81 9.8 4.7 9.1 6.4 0.2 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC-167 PF15188.1 AJZ75218.1 - 1.1 9.3 4.8 0.94 9.4 1.0 2.2 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Phage_GP20 PF06810.6 AJZ75218.1 - 1.3 8.4 5.5 7.9 5.8 0.2 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Fib_alpha PF08702.5 AJZ75218.1 - 3 7.9 5.4 5.7 7.0 0.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HATPase_c PF02518.21 AJZ75220.1 - 4.9e-24 84.1 0.1 8.4e-24 83.4 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJZ75220.1 - 1.1e-11 44.5 0.0 2.3e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJZ75220.1 - 2.3e-10 40.0 0.4 4.7e-10 39.0 0.3 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 AJZ75220.1 - 5.6e-07 29.3 0.4 1.2e-06 28.2 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJZ75220.1 - 1.3e-05 24.9 0.0 3.5e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain DUF1859 PF08948.5 AJZ75220.1 - 0.094 12.4 0.0 8 6.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1859) DREV PF05219.7 AJZ75220.1 - 0.094 11.5 0.1 0.55 9.0 0.1 1.9 2 0 0 2 2 2 0 DREV methyltransferase DUF1993 PF09351.5 AJZ75220.1 - 0.12 12.3 0.4 0.39 10.6 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) CagY_M PF07337.6 AJZ75220.1 - 0.22 11.0 1.8 0.38 10.2 1.2 1.4 1 0 0 1 1 1 0 DC-EC Repeat EcoEI_R_C PF08463.5 AJZ75221.1 - 0.018 14.9 0.1 0.021 14.7 0.1 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal GIY-YIG PF01541.19 AJZ75221.1 - 0.026 14.9 0.6 0.044 14.1 0.4 1.4 1 1 0 1 1 1 0 GIY-YIG catalytic domain TFIIB PF00382.14 AJZ75222.1 - 1.5e-35 120.7 7.2 3.3e-19 68.4 0.3 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJZ75222.1 - 1.9e-08 33.4 0.3 3.1e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 AJZ75222.1 - 2e-05 24.1 0.3 0.0012 18.3 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 AJZ75222.1 - 0.00029 19.9 1.2 0.00056 19.0 0.9 1.5 1 0 0 1 1 1 1 zinc-ribbon domain Rrf2 PF02082.15 AJZ75222.1 - 0.031 14.3 0.3 3.8 7.6 0.1 2.9 2 1 1 3 3 3 0 Transcriptional regulator DZR PF12773.2 AJZ75222.1 - 0.055 13.2 1.2 0.11 12.3 0.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_S27e PF01667.12 AJZ75222.1 - 0.11 12.0 1.2 0.26 10.8 0.9 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 UPF0547 PF10571.4 AJZ75222.1 - 1.3 8.7 6.3 8.1 6.2 4.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 AJZ75222.1 - 1.5 8.3 3.9 4.9 6.7 2.7 1.8 1 1 0 1 1 1 0 zinc-ribbon domain TrmB PF01978.14 AJZ75224.1 - 2.5e-13 49.4 0.0 1.2e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 AJZ75224.1 - 0.00073 19.1 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Regulator_TrmB PF11495.3 AJZ75224.1 - 0.00096 18.1 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_24 PF13412.1 AJZ75224.1 - 0.0021 17.3 0.0 0.0076 15.6 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding DUF3103 PF11301.3 AJZ75224.1 - 0.049 12.3 0.3 0.081 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) HTH_IclR PF09339.5 AJZ75224.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain RNA_pol_A_CTD PF03118.10 AJZ75224.1 - 0.19 11.1 3.1 0.37 10.2 0.2 2.7 3 0 0 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain TPR_11 PF13414.1 AJZ75226.1 - 5.3e-11 42.0 3.3 6e-07 29.0 0.6 2.5 2 0 0 2 2 2 2 TPR repeat Peptidase_M10 PF00413.19 AJZ75226.1 - 3e-09 36.8 0.2 8.1e-09 35.3 0.2 1.7 1 1 0 1 1 1 1 Matrixin TPR_1 PF00515.23 AJZ75226.1 - 4.1e-09 35.6 4.6 0.034 13.7 0.9 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 AJZ75226.1 - 8.3e-09 34.7 5.8 0.00048 19.8 0.6 3.8 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AJZ75226.1 - 6.4e-08 32.5 0.0 0.0016 18.9 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ75226.1 - 1.9e-07 31.3 0.4 0.0012 19.0 0.1 2.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 AJZ75226.1 - 2.3e-07 30.7 6.7 0.0016 18.7 0.2 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ75226.1 - 4.3e-07 29.7 0.5 0.00081 19.2 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AJZ75226.1 - 7e-07 29.7 0.0 2.9e-05 24.5 0.0 2.5 1 1 2 3 3 3 1 Tetratricopeptide repeat Reprolysin_5 PF13688.1 AJZ75226.1 - 1.8e-05 24.7 0.4 4.4e-05 23.5 0.3 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 AJZ75226.1 - 6.6e-05 23.0 0.7 0.00015 21.8 0.1 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 AJZ75226.1 - 0.00098 18.9 1.6 0.0034 17.1 0.1 2.2 2 0 0 2 2 2 1 Peptidase family M54 Peptidase_M66 PF10462.4 AJZ75226.1 - 0.0013 17.6 0.1 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M66 Fis1_TPR_C PF14853.1 AJZ75226.1 - 0.0024 17.6 0.4 0.067 13.0 0.0 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Reprolysin_3 PF13582.1 AJZ75226.1 - 0.0036 17.8 1.1 0.0098 16.4 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 AJZ75226.1 - 0.0037 16.8 0.1 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TPR_17 PF13431.1 AJZ75226.1 - 0.0071 16.4 5.3 0.08 13.1 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat Peptidase_M57 PF12388.3 AJZ75226.1 - 0.016 14.5 0.1 0.039 13.2 0.1 1.7 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF4363 PF14276.1 AJZ75226.1 - 0.042 13.5 0.2 0.042 13.5 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) TPR_7 PF13176.1 AJZ75226.1 - 0.049 13.4 0.3 0.44 10.4 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_18 PF13512.1 AJZ75226.1 - 0.053 13.5 3.8 0.12 12.3 1.6 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 AJZ75226.1 - 0.057 13.5 0.3 0.057 13.5 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 P4Ha_N PF08336.6 AJZ75226.1 - 0.071 12.9 0.2 3.2 7.5 0.0 2.5 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Alkyl_sulf_dimr PF14863.1 AJZ75226.1 - 0.12 12.5 1.8 0.13 12.4 0.2 1.7 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_8 PF13181.1 AJZ75226.1 - 0.17 11.7 9.8 7.5 6.5 0.8 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 AJZ75226.1 - 2.2 8.1 9.9 0.16 11.7 2.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat BPL_LplA_LipB PF03099.14 AJZ75227.1 - 1.2e-19 70.5 0.1 2.5e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.7 AJZ75227.1 - 6.8e-17 60.8 0.2 1.8e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 HTH domain BPL_C PF02237.12 AJZ75227.1 - 3.6e-07 29.7 0.3 8.5e-07 28.5 0.2 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain HTH_24 PF13412.1 AJZ75227.1 - 0.012 14.9 0.1 0.031 13.6 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding UPF0122 PF04297.9 AJZ75227.1 - 0.016 15.2 0.8 0.046 13.7 0.1 2.1 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4_2 PF08281.7 AJZ75227.1 - 0.033 13.6 0.0 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Complex1_LYR_2 PF13233.1 AJZ75227.1 - 0.12 12.8 0.0 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 Complex1_LYR-like HTH_10 PF04967.7 AJZ75227.1 - 0.12 11.9 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain GalP_UDP_transf PF01087.17 AJZ75227.1 - 0.15 12.1 0.0 7.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain HTH_34 PF13601.1 AJZ75228.1 - 6.6e-08 32.4 0.3 1e-07 31.8 0.2 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.2 AJZ75228.1 - 5.1e-06 26.0 0.0 8.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 AJZ75228.1 - 1.3e-05 25.4 0.0 1.9e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_45 PF14947.1 AJZ75228.1 - 2.3e-05 24.1 0.9 0.00011 21.9 0.6 1.9 1 1 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.14 AJZ75228.1 - 5.3e-05 22.8 0.1 8.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 AJZ75228.1 - 0.00015 21.2 0.7 0.00024 20.5 0.5 1.5 1 1 0 1 1 1 1 TFIIE alpha subunit MarR PF01047.17 AJZ75228.1 - 0.0012 18.5 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 MarR family DUF4423 PF14394.1 AJZ75228.1 - 0.0015 18.1 0.2 0.0027 17.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_24 PF13412.1 AJZ75228.1 - 0.0032 16.8 0.6 0.0061 15.9 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 AJZ75228.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Hydrolase_3 PF08282.7 AJZ75228.1 - 0.012 15.1 0.3 0.016 14.8 0.2 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PadR PF03551.9 AJZ75228.1 - 0.016 14.9 0.2 0.032 13.9 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2250 PF10007.4 AJZ75228.1 - 0.017 15.0 0.3 0.036 13.9 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Rrf2 PF02082.15 AJZ75228.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator DUF1018 PF06252.7 AJZ75228.1 - 0.024 15.1 0.5 0.034 14.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Ribonuclease_3 PF00636.21 AJZ75228.1 - 0.027 14.9 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease III domain HemN_C PF06969.11 AJZ75228.1 - 0.034 14.2 0.1 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 HemN C-terminal domain RB_A PF01858.12 AJZ75228.1 - 0.037 13.7 0.6 0.48 10.0 0.3 2.0 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain DER1 PF04511.10 AJZ75228.1 - 0.077 12.4 0.5 0.1 12.0 0.3 1.1 1 0 0 1 1 1 0 Der1-like family HTH_Crp_2 PF13545.1 AJZ75228.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain CDC37_C PF08564.5 AJZ75228.1 - 0.14 12.0 1.7 0.22 11.3 1.2 1.3 1 0 0 1 1 1 0 Cdc37 C terminal domain ORF6C PF10552.4 AJZ75228.1 - 2.4 7.8 5.8 15 5.3 1.5 2.1 2 0 0 2 2 2 0 ORF6C domain CoA_binding_2 PF13380.1 AJZ75229.1 - 2.9e-40 137.0 0.3 3.3e-40 136.8 0.2 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 AJZ75229.1 - 1.9e-07 31.4 0.0 3.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain TroA PF01297.12 AJZ75229.1 - 0.015 14.5 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Periplasmic solute binding protein family Glyco_hydro_57 PF03065.10 AJZ75229.1 - 0.039 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 SpoU_sub_bind PF08032.7 AJZ75229.1 - 0.14 12.3 0.4 0.51 10.5 0.1 1.9 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Pterin_4a PF01329.14 AJZ75230.1 - 0.069 12.9 0.1 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase MMR_HSR1_C PF08438.5 AJZ75231.1 - 3.3e-34 117.3 0.1 7.2e-34 116.3 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 AJZ75231.1 - 9.6e-17 61.0 0.0 4.6e-16 58.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 AJZ75231.1 - 4.8e-09 35.9 0.0 9.9e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 AJZ75231.1 - 2.5e-05 23.6 0.1 0.00055 19.2 0.1 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 AJZ75231.1 - 0.00062 19.2 0.7 0.19 11.1 0.1 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AJZ75231.1 - 0.00079 19.2 0.9 0.32 10.8 0.0 2.7 2 1 1 3 3 3 2 Dynamin family Miro PF08477.8 AJZ75231.1 - 0.014 15.8 0.0 0.14 12.6 0.0 2.5 3 0 0 3 3 3 0 Miro-like protein tRNA-synt_1e PF01406.14 AJZ75232.1 - 5.6e-120 400.0 1.4 7e-120 399.7 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 AJZ75232.1 - 2e-14 53.0 0.2 7.6e-08 31.4 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 AJZ75232.1 - 5.9e-09 36.0 0.3 1.3e-08 34.9 0.2 1.6 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.17 AJZ75232.1 - 1.8e-07 29.5 0.0 4.9e-06 24.8 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 AJZ75232.1 - 4.7e-07 28.8 0.5 0.0017 17.0 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (K) NAD_synthase PF02540.12 AJZ75233.1 - 2.2e-77 259.2 0.1 2.6e-77 259.0 0.1 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 AJZ75233.1 - 0.00012 20.7 0.0 0.13 10.7 0.0 2.3 2 0 0 2 2 2 2 tRNA methyl transferase Asn_synthase PF00733.16 AJZ75233.1 - 0.0028 17.1 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AJZ75233.1 - 0.022 14.0 0.0 0.057 12.6 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.15 AJZ75233.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 PP-loop family HTH_25 PF13413.1 AJZ75233.1 - 0.081 12.5 0.1 8.9 6.0 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain Rieske PF00355.21 AJZ75234.1 - 1.2e-12 47.2 0.0 1.3e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AJZ75234.1 - 6.6e-11 41.8 0.0 8.2e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain AdoHcyase PF05221.12 AJZ75235.1 - 1e-56 191.8 0.4 1.3e-56 191.5 0.2 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 AJZ75235.1 - 3.5e-55 186.2 1.1 3.5e-55 186.2 0.8 2.1 3 0 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 AJZ75235.1 - 3.2e-09 36.1 1.1 1.4e-08 34.0 0.3 2.3 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 AJZ75235.1 - 6.6e-06 25.5 0.2 1.3e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 AJZ75235.1 - 0.022 14.7 0.1 0.065 13.2 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.16 AJZ75235.1 - 0.11 12.0 1.9 0.23 11.0 0.2 2.2 2 1 1 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase tRNA-synt_1g PF09334.6 AJZ75236.1 - 7.5e-134 446.2 0.3 1e-133 445.8 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AJZ75236.1 - 1.1e-17 63.2 0.4 3.4e-06 25.3 0.0 4.1 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 AJZ75236.1 - 8.9e-12 44.7 0.1 3.2e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 AJZ75236.1 - 1.3e-06 27.3 0.1 0.003 16.2 0.0 3.3 3 0 0 3 3 3 2 tRNA synthetases class I (K) Anticodon_1 PF08264.8 AJZ75236.1 - 4.9e-06 26.3 0.1 9.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA FhuF PF06276.7 AJZ75236.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter tRNA-synt_1d PF00750.14 AJZ75236.1 - 0.062 12.1 0.0 0.35 9.6 0.0 2.1 1 1 1 2 2 2 0 tRNA synthetases class I (R) zf-ribbon_3 PF13248.1 AJZ75236.1 - 0.17 11.1 7.7 11 5.4 5.3 2.4 1 1 0 1 1 1 0 zinc-ribbon domain PolC_DP2 PF03833.8 AJZ75236.1 - 0.28 8.8 0.7 0.38 8.3 0.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF726 PF05277.7 AJZ75237.1 - 1e-10 41.0 0.0 1.3e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.7 AJZ75237.1 - 5.1e-09 35.8 0.0 7.6e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 AJZ75237.1 - 0.0016 18.0 0.1 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 AJZ75237.1 - 0.0016 18.2 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF676 PF05057.9 AJZ75237.1 - 0.0041 16.4 0.3 0.0088 15.3 0.1 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 AJZ75237.1 - 0.0074 16.0 0.0 0.0092 15.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 AJZ75237.1 - 0.012 14.5 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 AJZ75237.1 - 0.087 12.2 0.2 0.16 11.3 0.2 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Tup_N PF08581.5 AJZ75238.1 - 0.023 14.9 4.0 0.7 10.1 1.7 3.1 1 1 1 2 2 2 0 Tup N-terminal DUF3610 PF12272.3 AJZ75238.1 - 0.17 11.4 5.0 1.2 8.8 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3610) Tricorn_C1 PF14684.1 AJZ75238.1 - 0.88 9.4 4.4 16 5.4 0.2 3.0 3 0 0 3 3 3 0 Tricorn protease C1 domain IlvN PF07991.7 AJZ75239.1 - 5.6e-67 224.2 1.0 7.7e-67 223.7 0.7 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 AJZ75239.1 - 8.9e-49 165.1 0.2 1.5e-48 164.4 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 AJZ75239.1 - 7.3e-06 25.2 0.1 1.3e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 AJZ75239.1 - 5e-05 23.1 0.4 0.00012 21.9 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AJZ75239.1 - 6.9e-05 23.1 0.2 0.00015 22.1 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 AJZ75239.1 - 0.0061 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain B12-binding PF02310.14 AJZ75240.1 - 8.3e-18 64.4 0.0 1e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 B12 binding domain Ocnus PF05005.10 AJZ75240.1 - 0.00015 21.5 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Glyco_transf_28 PF03033.15 AJZ75240.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain RsmJ PF04378.8 AJZ75240.1 - 0.16 10.9 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA small subunit methyltransferase D, RsmJ Peptidase_M1 PF01433.15 AJZ75241.1 - 5.8e-140 466.7 2.7 9e-140 466.1 1.9 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 AJZ75241.1 - 3.1e-65 220.5 0.3 1e-64 218.8 0.0 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AJZ75241.1 - 3.2e-17 62.7 0.1 7.7e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2265 PF10023.4 AJZ75241.1 - 0.028 13.5 1.6 0.072 12.2 0.1 2.1 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) HEAT_2 PF13646.1 AJZ75241.1 - 0.19 12.0 0.0 0.53 10.6 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats DUF4198 PF10670.4 AJZ75242.1 - 0.013 15.4 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) DUF3172 PF11371.3 AJZ75242.1 - 0.13 11.8 0.1 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) ArgK PF03308.11 AJZ75243.1 - 5.2e-74 248.3 7.4 6.3e-74 248.1 5.1 1.1 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 AJZ75243.1 - 1.1e-07 31.5 0.1 2.1e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 AJZ75243.1 - 7.1e-06 25.7 0.7 0.017 14.7 0.1 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 AJZ75243.1 - 1.1e-05 24.6 0.0 3.3e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 KAP family P-loop domain DUF258 PF03193.11 AJZ75243.1 - 0.0025 17.0 0.7 0.0069 15.5 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AJZ75243.1 - 0.003 17.5 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 AJZ75243.1 - 0.0056 16.1 0.1 0.0084 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain NB-ARC PF00931.17 AJZ75243.1 - 0.0069 15.2 3.4 0.012 14.4 0.1 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_17 PF13207.1 AJZ75243.1 - 0.0072 17.1 1.9 0.037 14.8 0.2 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 AJZ75243.1 - 0.0085 15.8 0.1 0.018 14.7 0.1 1.7 1 0 0 1 1 1 1 NTPase MobB PF03205.9 AJZ75243.1 - 0.0093 15.6 3.4 0.023 14.3 0.2 2.9 3 1 1 4 4 4 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 AJZ75243.1 - 0.013 15.2 1.8 0.15 11.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 AJZ75243.1 - 0.013 14.5 0.2 0.038 13.0 0.1 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 AJZ75243.1 - 0.02 14.4 0.6 0.042 13.4 0.3 1.6 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 AJZ75243.1 - 0.021 15.2 0.9 1.4 9.4 0.1 2.9 1 1 1 2 2 2 0 Miro-like protein PRK PF00485.13 AJZ75243.1 - 0.028 13.9 1.7 0.039 13.5 0.2 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 AJZ75243.1 - 0.028 14.0 0.2 0.079 12.6 0.1 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_23 PF13476.1 AJZ75243.1 - 0.036 14.3 7.3 1 9.6 0.5 2.3 2 1 0 2 2 2 0 AAA domain CCDC50_N PF15295.1 AJZ75243.1 - 0.051 13.4 3.1 0.097 12.5 2.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus ABC_tran PF00005.22 AJZ75243.1 - 0.055 13.7 3.9 0.099 12.9 0.6 2.4 2 1 0 2 2 2 0 ABC transporter IIGP PF05049.8 AJZ75243.1 - 0.057 12.2 0.3 0.057 12.2 0.2 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_35 PF14516.1 AJZ75243.1 - 0.057 12.0 0.1 0.12 11.0 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 AJZ75243.1 - 0.058 13.3 2.8 0.18 11.7 1.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 AJZ75243.1 - 0.076 12.5 0.8 0.18 11.3 0.6 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 AJZ75243.1 - 0.34 10.7 2.2 0.36 10.6 0.4 1.9 2 0 0 2 2 1 0 Part of AAA domain PNPase PF03726.9 AJZ75243.1 - 0.55 10.5 4.9 3.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain AAA_18 PF13238.1 AJZ75243.1 - 2.8 8.2 5.5 0.73 10.1 0.4 2.5 2 2 0 2 2 2 0 AAA domain MM_CoA_mutase PF01642.17 AJZ75244.1 - 5.5e-189 628.5 1.0 6.6e-189 628.3 0.7 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase DUF2590 PF10761.4 AJZ75244.1 - 0.1 12.3 0.1 0.39 10.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2590) DUF2203 PF09969.4 AJZ75244.1 - 0.13 12.4 1.3 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Glyoxalase_4 PF13669.1 AJZ75245.1 - 3.3e-24 84.9 0.0 3.8e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 AJZ75245.1 - 4.1e-12 46.3 0.0 4.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AJZ75245.1 - 5.7e-12 45.7 0.0 6.2e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 AJZ75245.1 - 5.2e-08 33.4 0.0 6.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain YecM PF06185.7 AJZ75245.1 - 0.078 12.1 0.1 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 YecM protein CBS PF00571.23 AJZ75246.1 - 2.1e-16 59.4 0.6 2e-10 40.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain HTH_3 PF01381.17 AJZ75246.1 - 3.2e-14 52.5 0.4 6.1e-14 51.6 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.2 AJZ75246.1 - 2.1e-10 40.5 0.4 5.2e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.1 AJZ75246.1 - 6e-09 35.9 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 AJZ75246.1 - 0.0012 18.3 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 AJZ75246.1 - 0.0041 16.3 0.9 0.0083 15.4 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_26 PF13443.1 AJZ75246.1 - 0.019 15.1 0.1 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.1 AJZ75246.1 - 0.051 13.3 0.5 0.23 11.3 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 AJZ75246.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MerR PF00376.18 AJZ75246.1 - 0.076 12.5 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein HTH_24 PF13412.1 AJZ75246.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Response_reg PF00072.19 AJZ75247.1 - 5.9e-13 48.7 0.0 1e-12 48.0 0.0 1.5 1 1 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.6 AJZ75247.1 - 0.0021 18.2 0.1 0.0054 16.8 0.1 1.6 1 1 0 1 1 1 1 Flagellar regulatory protein FleQ CobA_CobO_BtuR PF02572.10 AJZ75247.1 - 0.0076 15.8 0.1 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Fibrinogen_aC PF12160.3 AJZ75247.1 - 0.032 13.7 0.1 0.047 13.1 0.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha C domain Glyco_hydro_67C PF07477.7 AJZ75247.1 - 0.032 13.6 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus PEP-utilizers_C PF02896.13 AJZ75248.1 - 3.1e-88 295.4 0.0 5.9e-88 294.5 0.0 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.14 AJZ75248.1 - 2.8e-60 204.1 0.0 8.8e-60 202.4 0.0 1.7 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 AJZ75248.1 - 1.3e-23 82.3 0.9 3.4e-23 81.0 0.6 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Phage_connect_1 PF05135.8 AJZ75248.1 - 0.011 15.9 0.0 0.092 12.9 0.0 2.5 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein TIM PF00121.13 AJZ75249.1 - 8.1e-24 84.0 1.3 1.6e-21 76.5 0.9 2.0 1 1 0 1 1 1 1 Triosephosphate isomerase ThiG PF05690.9 AJZ75249.1 - 0.00035 19.7 0.2 0.00067 18.8 0.1 1.6 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.13 AJZ75249.1 - 0.009 14.8 0.1 0.014 14.2 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IGPS PF00218.16 AJZ75249.1 - 0.026 13.5 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase PcrB PF01884.12 AJZ75249.1 - 0.038 13.2 2.1 0.089 12.0 0.8 2.0 2 1 1 3 3 3 0 PcrB family NMO PF03060.10 AJZ75249.1 - 0.066 12.3 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Keratin PF02422.11 AJZ75249.1 - 0.1 12.6 0.1 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Keratin TrmB PF01978.14 AJZ75250.1 - 1.7e-13 50.0 0.0 3.4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 AJZ75250.1 - 9.4e-05 21.9 0.1 0.00034 20.1 0.1 1.9 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.1 AJZ75250.1 - 9.7e-05 21.6 0.2 0.00019 20.7 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 AJZ75250.1 - 0.00016 21.3 0.0 0.00048 19.7 0.0 1.8 1 0 0 1 1 1 1 MarR family Mig-14 PF07395.6 AJZ75250.1 - 0.00055 19.0 0.2 0.045 12.7 0.0 2.1 2 0 0 2 2 2 1 Mig-14 MarR_2 PF12802.2 AJZ75250.1 - 0.00064 19.3 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.2 AJZ75250.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_34 PF13601.1 AJZ75250.1 - 0.023 14.7 0.1 0.19 11.7 0.0 2.5 3 1 0 3 3 3 0 Winged helix DNA-binding domain HTH_5 PF01022.15 AJZ75250.1 - 0.046 13.3 0.2 0.23 11.1 0.0 2.2 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family B-block_TFIIIC PF04182.7 AJZ75250.1 - 0.077 12.8 0.8 7.8 6.4 0.0 2.9 2 1 0 2 2 2 0 B-block binding subunit of TFIIIC HTH_AsnC-type PF13404.1 AJZ75250.1 - 0.088 12.3 0.1 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Fe_dep_repress PF01325.14 AJZ75250.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain COG5 PF10392.4 AJZ75250.1 - 0.11 12.4 0.7 0.22 11.4 0.5 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 T2SF PF00482.18 AJZ75251.1 - 6.9e-16 58.2 0.2 6.9e-16 58.2 0.1 1.8 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein F T2SF PF00482.18 AJZ75252.1 - 1.1e-13 51.2 0.3 1.1e-13 51.2 0.2 3.4 4 0 0 4 4 4 1 Type II secretion system (T2SS), protein F DUF4064 PF13273.1 AJZ75252.1 - 0.0064 16.5 1.2 0.0064 16.5 0.8 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4064) UPF0104 PF03706.8 AJZ75252.1 - 0.012 14.8 10.9 0.12 11.6 0.9 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) DUF2207 PF09972.4 AJZ75252.1 - 0.54 8.7 7.0 1.7 7.1 0.4 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) NfeD PF01957.13 AJZ75252.1 - 4.4 7.4 17.2 1 9.4 2.3 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Zn-ribbon_8 PF09723.5 AJZ75253.1 - 0.037 13.9 7.6 2.2 8.2 0.2 3.9 4 0 0 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1 PF03811.8 AJZ75253.1 - 0.047 13.1 6.7 0.7 9.4 0.0 3.8 4 0 0 4 4 4 0 InsA N-terminal domain zinc-ribbons_6 PF07191.7 AJZ75253.1 - 0.089 12.5 8.7 1 9.1 3.2 3.0 2 1 0 2 2 2 0 zinc-ribbons zf-Di19 PF05605.7 AJZ75253.1 - 0.091 12.8 0.5 0.091 12.8 0.3 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2197 PF09963.4 AJZ75253.1 - 0.13 12.2 1.4 0.75 9.7 1.0 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) Terminase_GpA PF05876.7 AJZ75253.1 - 0.18 10.1 2.1 0.27 9.5 1.4 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) C1_4 PF07975.7 AJZ75253.1 - 0.77 9.8 6.2 1.2 9.2 1.8 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain HypA PF01155.14 AJZ75253.1 - 2.2 7.9 7.2 12 5.5 0.2 3.0 1 1 3 4 4 4 0 Hydrogenase expression/synthesis hypA family zf-H2C2_2 PF13465.1 AJZ75253.1 - 4.7 7.6 6.5 5.7 7.4 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger double domain DZR PF12773.2 AJZ75253.1 - 7.7 6.4 9.3 45 3.9 2.4 3.0 1 1 1 2 2 2 0 Double zinc ribbon DUF1628 PF07790.6 AJZ75254.1 - 0.006 17.3 6.4 0.018 15.7 3.9 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1628) MIF PF01187.13 AJZ75254.1 - 0.078 13.0 0.3 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) SoxY PF13501.1 AJZ75257.1 - 0.12 12.4 0.0 9.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Sulfur oxidation protein SoxY FG-GAP PF01839.18 AJZ75258.1 - 0.011 15.4 0.2 0.028 14.0 0.1 1.7 1 0 0 1 1 1 0 FG-GAP repeat VCBS PF13517.1 AJZ75258.1 - 0.014 15.6 0.3 0.04 14.2 0.2 1.8 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Glyco_transf_36 PF06165.6 AJZ75259.1 - 0.036 13.8 0.1 13 5.6 0.0 3.2 2 1 1 3 3 3 0 Glycosyltransferase family 36 Head_binding PF09008.5 AJZ75259.1 - 0.59 10.1 4.2 59 3.7 0.1 4.2 4 0 0 4 4 4 0 Head binding DNA_pol_B PF00136.16 AJZ75260.1 - 1.6e-83 281.0 5.4 2.3e-83 280.5 3.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AJZ75260.1 - 2.4e-43 148.2 3.8 4.2e-43 147.4 2.7 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.1 AJZ75260.1 - 5.1e-07 29.6 0.9 2e-06 27.6 0.6 1.9 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 AJZ75260.1 - 1.5e-05 24.6 0.8 6.9e-05 22.4 0.3 2.4 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Rotamase_3 PF13616.1 AJZ75261.1 - 2.5e-27 95.4 0.0 2.8e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 AJZ75261.1 - 1.3e-26 93.1 0.0 1.5e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 AJZ75261.1 - 6.4e-10 39.7 0.0 7.4e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Pyridox_oxidase PF01243.15 AJZ75262.1 - 6.3e-13 48.5 0.0 8.1e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AJZ75262.1 - 7.1e-08 32.3 0.0 8.6e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.7 AJZ75262.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) FMN_bind_2 PF04299.7 AJZ75262.1 - 0.046 13.2 0.0 0.1 12.0 0.0 1.7 1 1 0 1 1 1 0 Putative FMN-binding domain Monellin PF09200.5 AJZ75262.1 - 0.16 11.6 3.8 11 5.8 0.1 3.1 2 1 1 3 3 3 0 Monellin DUF2951 PF11166.3 AJZ75263.1 - 0.017 14.9 0.2 0.028 14.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) PUCC PF03209.10 AJZ75263.1 - 0.024 13.3 0.0 0.026 13.2 0.0 1.0 1 0 0 1 1 1 0 PUCC protein SpoVAB PF13782.1 AJZ75263.1 - 0.052 13.5 0.1 0.086 12.8 0.1 1.3 1 1 0 1 1 1 0 Stage V sporulation protein AB DUF2203 PF09969.4 AJZ75264.1 - 9.7e-36 122.6 0.1 1.1e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) HAS-barrel PF09378.5 AJZ75264.1 - 0.083 12.8 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 HAS barrel domain Aldo_ket_red PF00248.16 AJZ75265.1 - 2.6e-31 108.5 0.0 9.4e-31 106.6 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family DUF321 PF03778.8 AJZ75265.1 - 0.065 12.6 0.8 0.065 12.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF321) Arch_flagellin PF01917.11 AJZ75266.1 - 0.015 14.9 3.3 0.022 14.4 2.3 1.2 1 0 0 1 1 1 0 Archaebacterial flagellin Dus PF01207.12 AJZ75267.1 - 1.4e-71 240.8 0.0 1.6e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 AJZ75267.1 - 4.5e-07 29.1 0.0 1.4e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family NanE PF04131.9 AJZ75267.1 - 0.00016 20.6 0.1 0.00068 18.6 0.0 2.0 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase SOR_SNZ PF01680.12 AJZ75267.1 - 0.031 13.8 0.1 0.063 12.8 0.1 1.4 1 0 0 1 1 1 0 SOR/SNZ family PEP_mutase PF13714.1 AJZ75267.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase YHS PF04945.8 AJZ75268.1 - 4.5e-12 45.6 1.5 5.4e-12 45.3 1.0 1.1 1 0 0 1 1 1 1 YHS domain Arc_trans_TRASH PF08394.5 AJZ75268.1 - 1.7e-06 28.0 2.5 2.3e-06 27.6 1.7 1.2 1 0 0 1 1 1 1 Archaeal TRASH domain ATPase-cat_bd PF12156.3 AJZ75268.1 - 7.2e-05 23.2 0.4 8.7e-05 22.9 0.3 1.1 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase YwqJ-deaminase PF14431.1 AJZ75268.1 - 0.097 12.5 0.3 0.11 12.3 0.2 1.1 1 0 0 1 1 1 0 YwqJ-like deaminase DUF2116 PF09889.4 AJZ75268.1 - 0.48 10.2 4.4 0.55 10.0 1.6 1.9 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Asn_synthase PF00733.16 AJZ75269.1 - 5.5e-26 91.5 0.0 1.1e-24 87.3 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase zf-ribbon_3 PF13248.1 AJZ75269.1 - 3e-05 23.0 2.4 0.00023 20.2 0.6 2.4 2 0 0 2 2 2 1 zinc-ribbon domain ATP_bind_3 PF01171.15 AJZ75269.1 - 4.3e-05 23.0 0.0 7.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 PP-loop family zinc_ribbon_2 PF13240.1 AJZ75269.1 - 9.4e-05 21.7 3.9 0.00045 19.6 0.6 2.4 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 AJZ75269.1 - 0.00025 20.8 1.9 0.00041 20.0 0.6 1.9 2 0 0 2 2 2 1 Double zinc ribbon NAD_synthase PF02540.12 AJZ75269.1 - 0.00069 18.5 0.1 0.0012 17.8 0.0 1.4 2 0 0 2 2 2 1 NAD synthase tRNA_Me_trans PF03054.11 AJZ75269.1 - 0.004 15.7 0.0 0.0067 15.0 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.8 AJZ75269.1 - 0.019 14.2 0.4 0.058 12.6 0.0 2.0 2 1 0 2 2 2 0 Queuosine biosynthesis protein QueC UPF0547 PF10571.4 AJZ75269.1 - 0.07 12.8 2.0 0.098 12.3 0.6 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.7 AJZ75269.1 - 0.9 9.3 6.6 0.85 9.4 0.7 2.6 2 0 0 2 2 2 0 zinc-ribbons HTH_3 PF01381.17 AJZ75270.1 - 5.6e-05 22.9 0.0 0.00016 21.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 AJZ75270.1 - 6e-05 23.0 0.1 0.00018 21.5 0.1 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.7 AJZ75270.1 - 0.028 14.0 0.1 0.072 12.7 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_23 PF13384.1 AJZ75270.1 - 0.035 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain RepB PF07506.6 AJZ75270.1 - 0.076 12.8 0.1 0.59 9.9 0.0 2.2 1 1 2 3 3 3 0 RepB plasmid partitioning protein Alba PF01918.16 AJZ75271.1 - 4.6e-05 22.9 0.0 7.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Alba RNA_pol_Rpb6 PF01192.17 AJZ75272.1 - 8.4e-12 44.6 3.6 1.4e-11 43.9 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb6 Turandot PF07240.6 AJZ75272.1 - 0.0045 16.4 0.1 0.0073 15.7 0.1 1.3 1 0 0 1 1 1 1 Stress-inducible humoral factor Turandot DUF465 PF04325.8 AJZ75272.1 - 0.014 15.0 0.3 0.041 13.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Lebercilin PF15619.1 AJZ75272.1 - 0.065 12.6 0.2 0.1 12.0 0.2 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease RNase_HII PF01351.13 AJZ75272.1 - 0.076 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease HII Cyclophil_like PF04126.8 AJZ75273.1 - 2.6e-13 49.6 0.0 3.4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin-like Ribosomal_S25 PF03297.10 AJZ75274.1 - 0.00015 21.7 3.8 0.00018 21.4 2.6 1.1 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 AJZ75274.1 - 0.00017 20.9 0.3 0.00025 20.3 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 AJZ75274.1 - 0.00027 20.5 0.1 0.00048 19.7 0.1 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 AJZ75274.1 - 0.00032 20.3 0.0 0.00045 19.8 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF977 PF06163.6 AJZ75274.1 - 0.00047 19.8 0.0 0.00062 19.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) MarR_2 PF12802.2 AJZ75274.1 - 0.012 15.2 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.5 AJZ75274.1 - 0.012 15.1 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF3489 PF11994.3 AJZ75274.1 - 0.026 14.4 0.9 0.043 13.7 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3489) EAP30 PF04157.11 AJZ75274.1 - 0.03 13.4 1.7 0.036 13.2 0.0 1.7 1 1 1 2 2 2 0 EAP30/Vps36 family HTH_11 PF08279.7 AJZ75274.1 - 0.052 13.2 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 HTH domain SID-1_RNA_chan PF13965.1 AJZ75274.1 - 0.085 11.0 1.0 0.092 10.8 0.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PY_rept_46 PF09689.5 AJZ75274.1 - 0.092 13.0 1.3 0.092 13.0 0.9 2.2 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) z-alpha PF02295.12 AJZ75274.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain Vfa1 PF08432.5 AJZ75274.1 - 0.51 10.3 7.2 0.57 10.1 5.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4519 PF15012.1 AJZ75274.1 - 1 9.3 3.9 1.9 8.4 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) AAA_22 PF13401.1 AJZ75275.1 - 0.044 13.9 0.2 0.049 13.7 0.2 1.1 1 0 0 1 1 1 0 AAA domain Nsp1_C PF05064.8 AJZ75275.1 - 0.045 13.3 2.3 0.18 11.4 2.2 1.5 2 0 0 2 2 2 0 Nsp1-like C-terminal region SlyX PF04102.7 AJZ75275.1 - 0.051 13.9 2.8 0.088 13.1 1.9 1.4 1 0 0 1 1 1 0 SlyX Serine_rich PF08824.5 AJZ75275.1 - 0.072 12.7 0.1 0.097 12.3 0.1 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain Glutaredoxin2_C PF04399.8 AJZ75275.1 - 0.073 12.6 0.7 0.11 12.0 0.3 1.4 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain Syntaxin_2 PF14523.1 AJZ75275.1 - 0.075 13.0 2.9 0.74 9.8 1.5 2.2 1 1 1 2 2 2 0 Syntaxin-like protein TFIID-18kDa PF02269.11 AJZ75275.1 - 0.081 12.7 0.2 0.081 12.7 0.1 1.7 2 1 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit DUF3139 PF11337.3 AJZ75275.1 - 0.14 12.4 0.3 0.24 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) ERp29 PF07749.7 AJZ75275.1 - 0.26 11.9 2.0 0.28 11.8 0.9 1.5 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Response_reg PF00072.19 AJZ75276.1 - 1.8e-25 89.1 1.6 2e-25 88.9 1.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Mic1 PF07035.7 AJZ75276.1 - 0.098 12.0 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like CBS PF00571.23 AJZ75277.1 - 1.2e-32 111.3 2.3 3.3e-08 33.1 0.1 4.1 4 0 0 4 4 4 4 CBS domain malic PF00390.14 AJZ75277.1 - 0.02 14.4 1.7 0.52 9.8 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain tRNA-Thr_ED PF08915.6 AJZ75280.1 - 2e-47 160.6 0.1 3.9e-47 159.6 0.1 1.5 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase tRNA-synt_2b PF00587.20 AJZ75280.1 - 9.2e-25 87.2 2.1 1.6e-24 86.3 1.5 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AJZ75280.1 - 2e-23 82.1 0.6 4.5e-23 81.0 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain Arginase PF00491.16 AJZ75281.1 - 4.8e-71 239.2 0.1 5.9e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family CDP-OH_P_transf PF01066.16 AJZ75282.1 - 1.1e-15 57.7 5.6 1.8e-15 57.0 3.9 1.5 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Ribosomal_S26e PF01283.14 AJZ75283.1 - 2.4e-31 108.3 0.8 2.6e-31 108.2 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e PHD PF00628.24 AJZ75283.1 - 0.087 12.5 0.2 9.7 5.9 0.0 2.2 2 0 0 2 2 2 0 PHD-finger zf-ribbon_3 PF13248.1 AJZ75283.1 - 0.092 11.9 0.1 0.092 11.9 0.1 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Fer4_10 PF13237.1 AJZ75283.1 - 0.19 11.5 1.4 3.3 7.5 1.0 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain RRN7 PF11781.3 AJZ75283.1 - 0.41 10.1 1.8 3 7.4 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_2 PF13240.1 AJZ75283.1 - 8.6 5.9 6.1 0.36 10.3 0.3 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Guanylate_cyc PF00211.15 AJZ75284.1 - 5.6e-20 71.4 0.2 9e-20 70.7 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HAMP PF00672.20 AJZ75284.1 - 6.2e-19 67.9 0.7 1.9e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 HAMP domain Cache_1 PF02743.13 AJZ75284.1 - 0.0013 18.2 0.2 0.004 16.6 0.0 1.9 2 0 0 2 2 2 1 Cache domain Baculo_PEP_N PF04512.7 AJZ75284.1 - 0.053 13.5 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus PfkB PF00294.19 AJZ75285.1 - 3.3e-08 33.0 0.0 1e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase NAD_kinase PF01513.16 AJZ75286.1 - 6.7e-32 110.4 0.6 8.8e-32 110.0 0.4 1.1 1 0 0 1 1 1 1 ATP-NAD kinase MarR PF01047.17 AJZ75286.1 - 0.00021 20.9 0.4 0.00055 19.5 0.3 1.7 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 AJZ75286.1 - 0.00087 19.5 1.3 0.0015 18.7 0.5 1.8 1 1 1 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.14 AJZ75286.1 - 0.00095 18.8 0.6 0.0033 17.1 0.2 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 AJZ75286.1 - 0.0013 18.0 0.1 0.003 16.9 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AJZ75286.1 - 0.0024 17.4 0.2 0.0055 16.3 0.1 1.6 1 0 0 1 1 1 1 MarR family RNA_pol_Rpc34 PF05158.7 AJZ75286.1 - 0.011 14.9 0.2 0.015 14.4 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit CTP_synth_N PF06418.9 AJZ75287.1 - 1.8e-120 401.1 0.4 2.4e-120 400.7 0.3 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 AJZ75287.1 - 3e-46 157.2 0.0 5.3e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AJZ75287.1 - 1.1e-12 47.9 0.1 2.7e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 AJZ75287.1 - 7.3e-06 25.5 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PQ-loop PF04193.9 AJZ75288.1 - 3.8e-10 39.1 3.6 3.8e-10 39.1 2.5 1.4 2 0 0 2 2 2 1 PQ loop repeat MtN3_slv PF03083.11 AJZ75288.1 - 2.3e-09 37.0 4.4 2.4e-09 36.9 3.0 1.0 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange LAB_N PF07578.6 AJZ75288.1 - 0.0011 18.8 0.8 0.0014 18.5 0.5 1.2 1 0 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain DUF2919 PF11143.3 AJZ75288.1 - 0.0042 16.9 1.6 0.005 16.6 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2919) DUF3054 PF11255.3 AJZ75288.1 - 0.13 12.0 1.7 0.14 12.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) DUF3784 PF12650.2 AJZ75288.1 - 0.56 10.1 4.7 0.59 10.1 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) Chordopox_A13L PF05961.6 AJZ75288.1 - 2.1 8.3 5.2 2.7 8.0 3.1 1.5 1 1 0 1 1 1 0 Chordopoxvirus A13L protein Trp_syntA PF00290.15 AJZ75289.1 - 3.6e-88 294.4 1.2 4e-88 294.2 0.8 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain DHO_dh PF01180.16 AJZ75289.1 - 6e-07 28.7 0.7 8.2e-07 28.2 0.5 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 AJZ75289.1 - 3.9e-06 26.3 0.2 1.1e-05 24.8 0.1 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein PcrB PF01884.12 AJZ75289.1 - 0.00093 18.5 1.4 0.017 14.3 0.9 2.4 1 1 0 1 1 1 1 PcrB family Ribul_P_3_epim PF00834.14 AJZ75289.1 - 0.0014 17.7 0.1 0.0021 17.1 0.1 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family FMN_dh PF01070.13 AJZ75289.1 - 0.0025 16.7 0.0 0.0098 14.7 0.0 1.8 1 1 1 2 2 2 1 FMN-dependent dehydrogenase IGPS PF00218.16 AJZ75289.1 - 0.01 14.9 0.0 0.028 13.4 0.0 1.8 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase NanE PF04131.9 AJZ75289.1 - 0.022 13.7 0.1 0.044 12.7 0.1 1.7 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 AJZ75289.1 - 0.056 12.5 0.1 0.22 10.5 0.0 1.9 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PALP PF00291.20 AJZ75290.1 - 8.9e-44 149.9 1.2 1.1e-43 149.6 0.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IGPS PF00218.16 AJZ75291.1 - 2e-69 233.4 0.5 2.4e-69 233.2 0.4 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.14 AJZ75291.1 - 0.00069 19.1 0.0 0.0015 18.0 0.0 1.6 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain AP_endonuc_2 PF01261.19 AJZ75291.1 - 0.0083 15.4 0.0 0.016 14.4 0.0 1.4 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Cellulase PF00150.13 AJZ75291.1 - 0.012 14.7 0.1 0.019 14.1 0.1 1.4 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF556 PF04476.8 AJZ75291.1 - 0.028 13.6 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF556) His_biosynth PF00977.16 AJZ75291.1 - 0.057 12.6 0.1 1 8.5 0.0 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein Glycos_transf_3 PF00591.16 AJZ75292.1 - 1.4e-83 280.2 1.4 1.4e-83 280.2 1.0 1.4 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 AJZ75292.1 - 6.4e-07 28.8 4.5 9.7e-07 28.2 0.9 2.4 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain GATase PF00117.23 AJZ75293.1 - 2e-56 190.5 0.1 2.2e-56 190.3 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AJZ75293.1 - 1.1e-09 38.0 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 SNO PF01174.14 AJZ75293.1 - 0.00032 20.3 0.1 0.00057 19.5 0.1 1.6 1 1 0 1 1 1 1 SNO glutamine amidotransferase family DJ-1_PfpI PF01965.19 AJZ75293.1 - 0.07 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family YPEB PF14620.1 AJZ75293.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 YpeB sporulation ABM PF03992.11 AJZ75296.1 - 2.3e-11 43.5 0.1 2.9e-11 43.2 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3291 PF11695.3 AJZ75296.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3291) ILVD_EDD PF00920.16 AJZ75297.1 - 7.4e-219 727.4 3.3 8.4e-219 727.2 2.3 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1263 PF06882.7 AJZ75297.1 - 0.0078 15.8 0.0 1 9.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1263) HIT PF01230.18 AJZ75298.1 - 7.8e-25 87.2 0.3 9.6e-25 86.9 0.2 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AJZ75298.1 - 7.8e-14 51.8 0.1 9.7e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AJZ75298.1 - 0.0031 17.1 1.0 0.006 16.2 0.7 1.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Mac PF12464.3 AJZ75299.1 - 0.0045 16.9 0.7 1.3 9.0 0.1 2.5 2 0 0 2 2 2 2 Maltose acetyltransferase DUF899 PF05988.7 AJZ75299.1 - 0.028 13.8 0.4 0.054 12.9 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) PPP5 PF08321.7 AJZ75299.1 - 0.064 13.2 4.6 0.14 12.1 1.4 2.3 1 1 1 2 2 2 0 PPP5 TPR repeat region YejG PF13989.1 AJZ75299.1 - 0.083 12.9 0.3 0.23 11.5 0.1 1.7 1 1 0 1 1 1 0 YejG-like protein DUF1664 PF07889.7 AJZ75299.1 - 1.5 8.5 11.2 0.49 10.1 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Response_reg PF00072.19 AJZ75300.1 - 1.9e-16 60.0 0.1 3.8e-16 59.0 0.1 1.5 1 1 0 1 1 1 1 Response regulator receiver domain HYR PF02494.11 AJZ75301.1 - 2.8e-14 52.8 15.2 4.6e-07 29.7 2.1 4.3 3 1 0 3 3 3 2 HYR domain FlgD_ig PF13860.1 AJZ75301.1 - 0.21 11.3 5.7 1.9 8.2 0.0 4.2 5 0 0 5 5 5 0 FlgD Ig-like domain Big_3_4 PF13754.1 AJZ75301.1 - 0.5 10.7 26.1 0.2 12.0 0.7 5.3 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) HYR PF02494.11 AJZ75302.1 - 2.5e-17 62.6 6.8 1e-08 35.0 0.3 3.1 2 0 0 2 2 2 2 HYR domain TSP_3 PF02412.13 AJZ75302.1 - 1.2e-05 24.6 16.5 0.00036 19.9 3.2 2.6 2 0 0 2 2 2 2 Thrombospondin type 3 repeat Big_3_4 PF13754.1 AJZ75302.1 - 0.00085 19.6 18.2 0.01 16.1 0.8 3.4 3 0 0 3 3 3 2 Bacterial Ig-like domain (group 3) COesterase PF00135.23 AJZ75302.1 - 0.19 10.3 7.4 0.34 9.5 5.2 1.3 1 0 0 1 1 1 0 Carboxylesterase family DUF4239 PF14023.1 AJZ75302.1 - 0.58 9.4 7.3 0.03 13.6 0.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) OppC_N PF12911.2 AJZ75303.1 - 0.081 12.3 0.1 0.097 12.0 0.1 1.1 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Cullin_Nedd8 PF10557.4 AJZ75304.1 - 0.025 14.4 0.2 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Cullin protein neddylation domain Thioredoxin_4 PF13462.1 AJZ75305.1 - 6.7e-33 113.9 0.0 7.9e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 AJZ75305.1 - 1.1e-13 51.1 0.2 1.8e-12 47.2 0.2 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 AJZ75305.1 - 1.4e-08 34.9 0.1 5e-08 33.1 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 AJZ75305.1 - 0.0096 15.5 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF4443 PF14544.1 AJZ75306.1 - 3.6e-06 26.8 0.0 6.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4443) CbtA PF09490.5 AJZ75307.1 - 3.1e-12 46.3 4.4 3.9e-12 45.9 3.0 1.1 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) EpsG PF14897.1 AJZ75307.1 - 0.038 12.9 1.3 0.054 12.4 0.9 1.3 1 0 0 1 1 1 0 EpsG family DUF4401 PF14351.1 AJZ75307.1 - 0.14 11.1 8.7 0.007 15.3 1.7 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4401) 7TMR-DISM_7TM PF07695.6 AJZ75307.1 - 0.73 9.4 13.5 0.015 14.9 4.5 1.8 2 1 0 2 2 2 0 7TM diverse intracellular signalling DUF2108 PF09881.4 AJZ75307.1 - 0.83 9.5 5.3 5.3 6.9 0.3 2.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2108) HTH_20 PF12840.2 AJZ75308.1 - 2.2e-07 30.5 0.1 3.3e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 AJZ75308.1 - 0.00021 20.9 0.1 0.00046 19.8 0.1 1.7 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 AJZ75308.1 - 0.0015 17.9 0.2 0.0018 17.7 0.2 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit DUF742 PF05331.6 AJZ75308.1 - 0.0052 16.3 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_7 PF02796.10 AJZ75308.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_11 PF08279.7 AJZ75308.1 - 0.025 14.2 0.1 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_IclR PF09339.5 AJZ75308.1 - 0.029 13.9 0.0 0.043 13.4 0.0 1.4 1 1 0 1 1 1 0 IclR helix-turn-helix domain PadR PF03551.9 AJZ75308.1 - 0.052 13.3 0.1 0.098 12.4 0.0 1.5 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family HTH_5 PF01022.15 AJZ75308.1 - 0.056 13.1 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF1492 PF07374.6 AJZ75308.1 - 0.057 13.5 0.1 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Mga PF05043.8 AJZ75308.1 - 0.082 13.1 0.1 0.58 10.4 0.0 2.0 2 0 0 2 2 2 0 Mga helix-turn-helix domain Sigma70_r4 PF04545.11 AJZ75308.1 - 0.13 11.5 0.0 0.58 9.5 0.0 2.0 1 1 0 2 2 2 0 Sigma-70, region 4 FUR PF01475.14 AJZ75309.1 - 0.00051 19.9 0.2 0.0007 19.5 0.1 1.4 1 1 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.14 AJZ75309.1 - 0.00052 19.6 0.0 0.00083 19.0 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Antigen_Bd37 PF11641.3 AJZ75309.1 - 0.0017 17.7 0.1 0.0022 17.2 0.1 1.2 1 0 0 1 1 1 1 Glycosylphosphatidylinositol-anchored merozoite surface protein HTH_20 PF12840.2 AJZ75309.1 - 0.0029 17.3 0.0 0.0039 16.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_36 PF13730.1 AJZ75309.1 - 0.0087 16.1 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2250 PF10007.4 AJZ75309.1 - 0.012 15.4 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DUF1492 PF07374.6 AJZ75309.1 - 0.044 13.8 0.7 0.07 13.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) PadR PF03551.9 AJZ75309.1 - 0.063 13.0 0.0 0.28 10.9 0.0 1.9 1 1 1 2 2 2 0 Transcriptional regulator PadR-like family TFIIE_alpha PF02002.12 AJZ75309.1 - 0.068 12.6 0.4 0.083 12.3 0.3 1.1 1 0 0 1 1 1 0 TFIIE alpha subunit Rrf2 PF02082.15 AJZ75309.1 - 0.077 13.1 0.1 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Transcriptional regulator DnaB_2 PF07261.6 AJZ75309.1 - 0.078 12.5 0.4 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 Replication initiation and membrane attachment FTR1 PF03239.9 AJZ75310.1 - 1.8e-19 69.8 20.4 1.2e-18 67.1 13.1 2.6 2 1 0 2 2 2 1 Iron permease FTR1 family DNAJ_related PF12339.3 AJZ75310.1 - 0.033 14.0 1.5 0.067 13.0 0.0 2.3 3 0 0 3 3 3 0 DNA-J related protein Hydantoinase_A PF01968.13 AJZ75311.1 - 3.8e-53 180.4 11.1 6.7e-53 179.6 3.9 3.1 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 AJZ75311.1 - 1.5e-23 83.1 9.4 3.1e-22 78.9 4.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 AJZ75311.1 - 4.2e-08 31.9 7.9 8.5e-06 24.3 0.8 2.8 3 0 0 3 3 3 2 MutL protein FGGY_N PF00370.16 AJZ75311.1 - 2.5e-05 23.7 1.7 7.2e-05 22.2 1.2 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 AJZ75311.1 - 0.00013 21.3 2.7 0.00074 18.8 1.1 2.7 1 1 1 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Peptidase_C30 PF05409.8 AJZ75311.1 - 0.021 13.8 0.1 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 FtsA PF14450.1 AJZ75311.1 - 1.4 8.7 21.3 2.6 7.9 5.8 4.0 3 2 0 3 3 3 0 Cell division protein FtsA Dicty_CAD PF05720.7 AJZ75312.1 - 0.017 14.7 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Cell-cell adhesion domain Cu-binding_MopE PF11617.3 AJZ75313.1 - 0.00025 20.7 4.4 0.00084 19.0 3.1 2.0 1 0 0 1 1 1 1 Protein metal binding site DUF1297 PF06973.7 AJZ75314.1 - 2.7e-72 242.0 0.0 3.5e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.7 AJZ75314.1 - 2.4e-44 150.0 0.0 5.5e-44 148.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) ATP-grasp_4 PF13535.1 AJZ75314.1 - 0.098 12.3 0.0 0.44 10.2 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain HTH_5 PF01022.15 AJZ75316.1 - 8.5e-09 34.9 0.0 1.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 AJZ75316.1 - 3.5e-07 29.9 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 AJZ75316.1 - 8.4e-07 28.2 0.0 1.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.14 AJZ75316.1 - 0.00022 20.8 0.1 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 AJZ75316.1 - 0.0033 16.9 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 TFIIE alpha subunit RepL PF05732.6 AJZ75316.1 - 0.0051 16.0 0.1 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) HTH_11 PF08279.7 AJZ75316.1 - 0.02 14.5 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 HTH domain Sigma70_r4 PF04545.11 AJZ75316.1 - 0.081 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_34 PF13601.1 AJZ75316.1 - 0.11 12.5 0.2 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR_2 PF12802.2 AJZ75316.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 MarR family SIMPL PF04402.9 AJZ75317.1 - 1.5e-50 171.9 1.6 2e-50 171.5 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Internalin_N PF12354.3 AJZ75317.1 - 0.28 10.8 2.8 0.76 9.4 0.1 2.8 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal Pyr_redox_2 PF07992.9 AJZ75320.1 - 1.8e-18 67.1 0.0 1.2e-17 64.4 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AJZ75320.1 - 6.3e-10 39.3 0.2 6.3e-07 29.7 0.2 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AJZ75320.1 - 0.0014 17.5 0.2 3.8 6.3 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AJZ75320.1 - 0.0025 17.6 0.1 0.071 12.8 0.0 2.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AJZ75320.1 - 0.061 13.3 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_2 PF00152.15 AJZ75321.1 - 7.1e-86 288.0 0.8 2e-85 286.5 0.6 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AJZ75321.1 - 1.3e-11 44.1 0.0 2.3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AJZ75321.1 - 0.0019 17.4 0.2 0.14 11.3 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) MotCF PF09158.5 AJZ75321.1 - 0.12 12.0 0.4 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage T4 MotA, C-terminal Glu-tRNAGln PF02686.10 AJZ75322.1 - 0.0065 16.2 0.4 0.013 15.3 0.2 1.6 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Vert_IL3-reg_TF PF06529.6 AJZ75322.1 - 0.028 13.3 0.0 0.031 13.2 0.0 1.0 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor Ubiq-assoc PF09145.5 AJZ75322.1 - 0.11 12.3 0.2 0.26 11.1 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-associated Amidase PF01425.16 AJZ75323.1 - 3.2e-136 454.7 0.0 3.6e-136 454.5 0.0 1.0 1 0 0 1 1 1 1 Amidase RDM PF11002.3 AJZ75323.1 - 0.067 12.8 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 RFPL defining motif (RDM) PTE PF02126.13 AJZ75323.1 - 0.067 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family GatB_N PF02934.10 AJZ75324.1 - 7.5e-99 330.2 0.0 2e-98 328.8 0.0 1.6 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 AJZ75324.1 - 3.4e-32 111.2 3.7 5.6e-32 110.5 2.6 1.4 1 0 0 1 1 1 1 GatB domain TMP_2 PF06791.8 AJZ75324.1 - 0.016 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein Saccharop_dh_N PF04455.7 AJZ75326.1 - 1.7e-36 124.4 0.2 3.4e-36 123.4 0.1 1.5 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region DPBB_1 PF03330.13 AJZ75328.1 - 0.005 16.7 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF576 PF04507.7 AJZ75328.1 - 0.08 11.8 0.0 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF576 Cob_adeno_trans PF01923.13 AJZ75329.1 - 1e-57 194.4 0.0 1.1e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Glyoxalase_2 PF12681.2 AJZ75330.1 - 4.9e-14 52.8 0.0 6.2e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AJZ75330.1 - 3.4e-09 36.7 0.0 4.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily U5_2-snRNA_bdg PF10597.4 AJZ75330.1 - 0.045 13.3 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 3-dmu-9_3-mt PF06983.8 AJZ75330.1 - 0.088 13.1 0.1 0.15 12.3 0.1 1.5 1 1 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase PTPS PF01242.14 AJZ75331.1 - 0.042 13.5 0.1 0.059 13.0 0.1 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase YcgR PF07317.7 AJZ75331.1 - 0.13 11.9 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar regulator YcgR FAM86 PF14904.1 AJZ75331.1 - 0.14 11.9 0.1 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function AsnC_trans_reg PF01037.16 AJZ75332.1 - 1.5e-08 34.2 0.0 1.6e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 AsnC family ACT_4 PF13291.1 AJZ75332.1 - 0.0091 16.3 0.0 0.018 15.3 0.0 1.5 1 1 1 2 2 2 1 ACT domain NB-ARC PF00931.17 AJZ75332.1 - 0.021 13.7 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain GYD PF08734.6 AJZ75332.1 - 0.084 12.6 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 GYD domain Glyoxalase_2 PF12681.2 AJZ75333.1 - 8.3e-18 64.9 0.0 1e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AJZ75333.1 - 1.3e-11 44.5 0.0 2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 AJZ75333.1 - 7.7e-05 22.6 0.0 0.00086 19.3 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF507 PF04368.8 AJZ75335.1 - 0.062 12.9 10.8 0.22 11.1 7.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF507) PALP PF00291.20 AJZ75336.1 - 4.9e-76 255.8 1.3 6.9e-76 255.4 0.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT_4 PF13291.1 AJZ75336.1 - 3.1e-05 24.2 0.3 8.7e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 ACT domain ACT PF01842.20 AJZ75336.1 - 0.00074 18.9 0.1 0.0018 17.6 0.1 1.7 1 0 0 1 1 1 1 ACT domain AIRC PF00731.15 AJZ75337.1 - 1.4e-60 202.9 0.4 1.8e-60 202.5 0.3 1.1 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 AJZ75338.1 - 6.9e-60 201.3 0.1 1e-59 200.7 0.1 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 AJZ75338.1 - 1.3e-16 60.9 0.1 1.9e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AJZ75338.1 - 2.2e-08 33.7 0.2 4.9e-08 32.5 0.1 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 AJZ75338.1 - 1.5e-06 27.2 0.0 6.4e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.6 AJZ75338.1 - 6.7e-06 25.6 0.2 1.8e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain DUF1297 PF06973.7 AJZ75338.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) GARS_A PF01071.14 AJZ75338.1 - 0.046 13.2 0.2 0.099 12.1 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.13 AJZ75338.1 - 0.078 12.9 0.8 0.39 10.7 0.0 2.3 2 1 0 2 2 2 0 TrkA-N domain TrmB PF01978.14 AJZ75339.1 - 4.1e-12 45.6 0.0 1.1e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 AJZ75339.1 - 5.7e-05 22.7 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 AJZ75339.1 - 0.00027 20.6 0.0 0.00053 19.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.2 AJZ75339.1 - 0.00039 20.0 0.0 0.00085 18.9 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.7 AJZ75339.1 - 0.021 14.4 0.2 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 HTH domain HTH_IclR PF09339.5 AJZ75339.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.1 AJZ75339.1 - 0.024 14.0 0.6 0.39 10.1 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding CD20 PF04103.10 AJZ75340.1 - 0.033 14.1 0.3 0.033 14.1 0.2 1.9 2 0 0 2 2 2 0 CD20-like family DUF202 PF02656.10 AJZ75340.1 - 0.041 14.0 0.6 0.26 11.5 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF3188 PF11384.3 AJZ75340.1 - 0.095 12.2 6.6 0.17 11.5 1.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) DUF3185 PF11381.3 AJZ75340.1 - 0.34 10.7 4.1 0.95 9.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) IncA PF04156.9 AJZ75340.1 - 3.5 7.1 7.6 0.9 9.1 0.1 2.2 2 0 0 2 2 2 0 IncA protein DUF4064 PF13273.1 AJZ75340.1 - 4.3 7.5 6.5 22 5.2 4.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) SNARE_assoc PF09335.6 AJZ75341.1 - 7.9e-21 74.5 5.3 7.9e-21 74.5 3.7 2.0 1 1 1 2 2 2 2 SNARE associated Golgi protein NTP_transferase PF00483.18 AJZ75342.1 - 5.9e-29 101.0 0.0 1.3e-28 99.9 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AJZ75342.1 - 5.3e-14 52.6 0.0 6.4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.14 AJZ75342.1 - 0.049 13.2 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase IspD PF01128.14 AJZ75342.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Bac_luciferase PF00296.15 AJZ75343.1 - 7.7e-54 182.8 0.0 9.4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Thiolase_C PF02803.13 AJZ75344.1 - 1.1e-13 50.6 0.1 3.1e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 AJZ75344.1 - 1.1e-06 27.8 0.1 2.9e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 AJZ75344.1 - 0.00031 20.3 0.0 0.00084 18.9 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 AJZ75344.1 - 0.00089 18.8 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 AJZ75344.1 - 0.047 13.5 0.3 0.62 9.9 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF35_N PF12172.3 AJZ75345.1 - 2.5e-07 30.3 0.2 6.7e-07 29.0 0.1 1.7 2 0 0 2 2 2 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF1272 PF06906.6 AJZ75345.1 - 0.0017 18.1 0.9 0.0033 17.2 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) Hjc PF01870.13 AJZ75346.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) Phytase PF02333.10 AJZ75346.1 - 0.046 12.4 0.0 0.053 12.2 0.0 1.1 1 0 0 1 1 1 0 Phytase GIT1_C PF12205.3 AJZ75347.1 - 0.0043 16.8 0.1 0.0053 16.5 0.1 1.2 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term Sec5 PF15469.1 AJZ75347.1 - 0.051 13.3 0.5 0.13 11.9 0.4 1.7 1 1 0 1 1 1 0 Exocyst complex component Sec5 Cortex-I_coil PF09304.5 AJZ75347.1 - 0.076 13.0 1.2 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil FlxA PF14282.1 AJZ75347.1 - 0.085 12.8 4.0 0.095 12.6 0.3 2.0 2 0 0 2 2 2 0 FlxA-like protein DUF3753 PF12575.3 AJZ75347.1 - 0.13 12.0 2.0 3.4 7.5 1.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3753) XPA_N PF01286.13 AJZ75348.1 - 0.015 14.9 0.1 0.035 13.7 0.1 1.6 1 0 0 1 1 1 0 XPA protein N-terminal PhnA_Zn_Ribbon PF08274.7 AJZ75348.1 - 0.31 10.8 1.9 0.87 9.4 1.3 1.9 1 1 0 1 1 1 0 PhnA Zinc-Ribbon DUF1938 PF09153.5 AJZ75349.1 - 0.087 12.6 0.3 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) Cation_efflux PF01545.16 AJZ75350.1 - 1.2e-43 149.2 9.4 1.5e-43 148.9 6.5 1.1 1 0 0 1 1 1 1 Cation efflux family Gp_dh_N PF00044.19 AJZ75351.1 - 5.2e-09 36.2 0.3 1.5e-07 31.4 0.1 2.7 2 1 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 AJZ75351.1 - 0.00039 20.3 0.0 0.00097 19.0 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 AJZ75351.1 - 0.00041 20.6 0.0 0.00073 19.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.7 AJZ75351.1 - 0.07 12.5 0.0 0.21 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_3 PF03447.11 AJZ75351.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Thioredoxin_4 PF13462.1 AJZ75353.1 - 1.5e-38 132.4 1.2 1.9e-38 132.0 0.2 1.5 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.15 AJZ75353.1 - 7.8e-18 64.7 0.4 1.3e-16 60.7 0.3 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 AJZ75353.1 - 2.3e-09 37.4 0.2 7.1e-09 35.8 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 AJZ75353.1 - 0.018 14.5 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.1 AJZ75353.1 - 0.049 13.7 0.4 2.3 8.3 0.3 2.4 1 1 0 1 1 1 0 Thioredoxin-like CxxCxxCC PF03692.10 AJZ75354.1 - 3.8e-09 36.9 5.2 3.4e-08 33.8 2.6 2.3 1 1 1 2 2 2 1 Putative zinc- or iron-chelating domain Haemolytic PF01809.13 AJZ75354.1 - 0.077 12.6 0.4 4.6 6.9 0.6 2.4 2 0 0 2 2 2 0 Haemolytic domain HMG_CoA_synt_C PF08540.5 AJZ75355.1 - 3.8e-33 115.1 0.2 5.5e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 AJZ75355.1 - 8.3e-32 110.1 0.1 1.4e-31 109.4 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal RsbU_N PF08673.5 AJZ75356.1 - 0.018 15.0 0.2 0.036 14.0 0.2 1.4 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain AAA_26 PF13500.1 AJZ75357.1 - 3.4e-41 141.0 0.0 3.8e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 AJZ75357.1 - 6.5e-05 22.4 2.0 0.00017 21.0 1.4 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.10 AJZ75357.1 - 0.038 13.7 0.1 0.69 9.5 0.0 2.2 2 0 0 2 2 2 0 NTPase Fer4_NifH PF00142.13 AJZ75357.1 - 0.077 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Aminotran_3 PF00202.16 AJZ75358.1 - 6.3e-85 285.0 0.8 7.4e-85 284.7 0.6 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 AJZ75358.1 - 0.036 13.1 0.1 0.12 11.4 0.0 1.8 2 1 0 2 2 2 0 Beta-eliminating lyase BATS PF06968.8 AJZ75359.1 - 1.7e-21 75.8 0.0 4.4e-21 74.5 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 AJZ75359.1 - 4.8e-18 65.8 0.4 3e-17 63.2 0.1 2.0 2 0 0 2 2 2 1 Radical SAM superfamily DUF1471 PF07338.8 AJZ75359.1 - 0.072 12.7 0.2 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) Aminotran_1_2 PF00155.16 AJZ75360.1 - 3.4e-52 177.5 0.0 3.9e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AJZ75360.1 - 2.1e-07 30.4 0.0 3.7e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AJZ75360.1 - 0.0011 17.3 0.0 0.0017 16.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.14 AJZ75360.1 - 0.038 12.3 0.1 0.23 9.7 0.0 1.9 2 0 0 2 2 2 0 Serine hydroxymethyltransferase Redoxin PF08534.5 AJZ75361.1 - 1.8e-09 37.2 0.0 3.5e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 AJZ75361.1 - 8.4e-08 31.9 0.1 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 AJZ75361.1 - 8.8e-05 22.5 0.3 0.00016 21.6 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin-like PspC PF04024.7 AJZ75361.1 - 0.11 11.9 0.6 0.47 9.9 0.2 2.0 2 0 0 2 2 2 0 PspC domain Thioredoxin PF00085.15 AJZ75361.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Snf7 PF03357.16 AJZ75362.1 - 0.28 10.5 8.0 0.62 9.4 5.6 1.6 1 1 0 1 1 1 0 Snf7 WbqC PF08889.6 AJZ75363.1 - 0.015 14.7 0.3 0.021 14.3 0.2 1.2 1 0 0 1 1 1 0 WbqC-like protein family SopA_C PF13979.1 AJZ75364.1 - 0.026 14.1 0.4 0.033 13.7 0.3 1.2 1 0 0 1 1 1 0 SopA-like catalytic domain HMD PF03201.11 AJZ75364.1 - 0.028 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase KMP11 PF03037.11 AJZ75364.1 - 0.039 14.5 2.3 0.7 10.5 0.2 2.4 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 Fib_alpha PF08702.5 AJZ75364.1 - 0.65 10.1 3.9 0.76 9.8 0.8 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FANCI_HD1 PF14679.1 AJZ75366.1 - 0.021 14.5 0.1 0.037 13.7 0.0 1.4 1 1 0 1 1 1 0 FANCI helical domain 1 DUF1456 PF07308.8 AJZ75366.1 - 0.074 13.0 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) DUF4577 PF15145.1 AJZ75368.1 - 0.019 14.8 0.5 0.031 14.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF898 PF05987.8 AJZ75368.1 - 0.074 11.9 7.3 0.11 11.3 5.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF1049 PF06305.6 AJZ75368.1 - 0.68 9.4 0.1 0.68 9.4 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) ATP-synt_8 PF00895.15 AJZ75368.1 - 4.3 7.6 5.0 0.65 10.2 0.4 2.0 2 0 0 2 2 2 0 ATP synthase protein 8 zf-IS66 PF13005.2 AJZ75369.1 - 0.014 15.3 3.2 1.2 9.2 0.1 2.7 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 DZR PF12773.2 AJZ75369.1 - 0.02 14.6 0.2 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-LYAR PF08790.6 AJZ75369.1 - 0.054 13.2 0.8 9.1 6.0 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger C1_4 PF07975.7 AJZ75369.1 - 0.057 13.4 0.2 6.6 6.8 0.0 2.1 2 0 0 2 2 2 0 TFIIH C1-like domain DUF35_N PF12172.3 AJZ75369.1 - 0.28 11.1 1.6 11 6.1 0.1 2.2 1 1 1 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Ribosomal_L6 PF00347.18 AJZ75370.1 - 5.6e-12 45.9 5.2 2.2e-05 24.8 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF4649 PF15507.1 AJZ75370.1 - 0.1 12.3 0.0 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4649) BON PF04972.12 AJZ75370.1 - 1.9 8.2 4.8 1.7 8.4 0.4 3.0 4 1 1 5 5 5 0 BON domain Ribosomal_S14 PF00253.16 AJZ75371.1 - 9e-16 56.9 4.2 1e-15 56.8 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-FPG_IleRS PF06827.9 AJZ75371.1 - 0.0097 15.5 2.8 0.02 14.5 1.9 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS IBR PF01485.16 AJZ75371.1 - 0.049 13.5 0.7 0.058 13.2 0.5 1.1 1 0 0 1 1 1 0 IBR domain DZR PF12773.2 AJZ75371.1 - 0.077 12.8 0.2 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Double zinc ribbon DUF1660 PF07874.6 AJZ75371.1 - 4.8 7.5 5.9 79 3.6 4.1 2.1 1 1 0 1 1 1 0 Prophage protein (DUF1660) Ribosomal_L5_C PF00673.16 AJZ75372.1 - 8.7e-24 83.0 0.0 1.8e-23 82.1 0.0 1.5 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AJZ75372.1 - 1.9e-11 43.5 0.3 5.4e-11 42.1 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_S4e PF00900.15 AJZ75373.1 - 8.7e-23 79.7 0.4 1.9e-22 78.7 0.3 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 AJZ75373.1 - 8.6e-13 47.9 1.6 1.6e-12 47.0 1.1 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 AJZ75373.1 - 0.00016 21.0 0.1 0.00052 19.4 0.1 1.9 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 AJZ75374.1 - 1.7e-06 27.4 0.3 5.2e-06 25.9 0.2 1.8 1 0 0 1 1 1 1 KOW motif Menin PF05053.8 AJZ75374.1 - 0.71 7.9 3.8 0.77 7.8 2.6 1.1 1 0 0 1 1 1 0 Menin Ribosomal_L14 PF00238.14 AJZ75375.1 - 5.5e-34 116.5 0.1 6.3e-34 116.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_S17 PF00366.15 AJZ75376.1 - 8.9e-15 54.4 2.8 1.2e-14 54.1 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 AlgF PF11182.3 AJZ75376.1 - 0.0087 15.7 0.1 0.0088 15.7 0.1 1.1 1 0 0 1 1 1 1 Alginate O-acetyl transferase AlgF G2F PF07474.7 AJZ75376.1 - 0.0093 15.3 0.2 0.011 15.0 0.1 1.1 1 0 0 1 1 1 1 G2F domain UPF0086 PF01868.11 AJZ75377.1 - 7.4e-20 70.3 0.1 9.1e-20 70.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_L29 PF00831.18 AJZ75378.1 - 3e-12 46.0 7.0 3.6e-12 45.7 4.8 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein Vps5 PF09325.5 AJZ75378.1 - 0.017 14.3 2.2 0.018 14.3 1.5 1.1 1 0 0 1 1 1 0 Vps5 C terminal like Bacillus_HBL PF05791.6 AJZ75378.1 - 0.018 14.3 0.9 0.02 14.2 0.6 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF3811 PF11656.3 AJZ75378.1 - 0.049 13.6 6.7 0.052 13.6 4.6 1.1 1 0 0 1 1 1 0 YjbD family (DUF3811) Snapin_Pallidin PF14712.1 AJZ75378.1 - 0.17 12.2 4.2 0.21 11.8 2.9 1.2 1 0 0 1 1 1 0 Snapin/Pallidin DUF1192 PF06698.6 AJZ75378.1 - 2.8 7.8 7.1 1.3 8.8 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) KH_2 PF07650.12 AJZ75379.1 - 1.3e-15 56.6 0.2 1.3e-15 56.6 0.1 2.8 3 0 0 3 3 3 1 KH domain Ribosomal_S3_C PF00189.15 AJZ75379.1 - 1.2e-13 51.0 0.2 3.4e-13 49.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_4 PF13083.1 AJZ75379.1 - 0.028 14.0 0.1 0.1 12.2 0.0 2.0 1 0 0 1 1 1 0 KH domain KH_1 PF00013.24 AJZ75379.1 - 0.028 14.0 2.4 0.17 11.5 0.3 2.9 3 0 0 3 3 3 0 KH domain KH_3 PF13014.1 AJZ75379.1 - 0.11 12.2 2.9 0.29 10.8 0.7 2.7 3 0 0 3 3 3 0 KH domain Ribosomal_L22 PF00237.14 AJZ75380.1 - 1e-31 108.9 1.0 1.2e-31 108.7 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S19 PF00203.16 AJZ75381.1 - 3e-24 84.4 0.6 4e-24 84.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Herpes_UL42 PF02282.11 AJZ75381.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) Ribosomal_L23 PF00276.15 AJZ75382.1 - 6.6e-12 45.2 0.9 1.4e-11 44.1 0.6 1.6 1 1 0 1 1 1 1 Ribosomal protein L23 DNA_mis_repair PF01119.14 AJZ75382.1 - 0.032 13.6 0.0 0.042 13.3 0.0 1.3 1 1 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain RRM_5 PF13893.1 AJZ75382.1 - 0.048 13.5 0.1 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L1 PF00687.16 AJZ75382.1 - 0.055 12.8 0.5 0.057 12.7 0.3 1.0 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family RRM_1 PF00076.17 AJZ75382.1 - 0.058 13.0 0.1 0.095 12.3 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) REGB_T4 PF10715.4 AJZ75382.1 - 0.065 13.3 0.1 0.096 12.7 0.1 1.4 1 1 1 2 2 2 0 Endoribonuclease RegB T4-bacteriophage encoded TPP_enzyme_M PF00205.17 AJZ75382.1 - 0.082 12.6 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Ribosomal_L4 PF00573.17 AJZ75383.1 - 6.1e-40 136.6 0.3 7.2e-40 136.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L3 PF00297.17 AJZ75384.1 - 1.2e-55 188.8 0.4 1.3e-55 188.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Methyltrn_RNA_3 PF02598.12 AJZ75385.1 - 1.9e-52 178.4 0.0 2.3e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 AJZ75385.1 - 2.9e-05 23.9 0.0 0.1 12.4 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family DUF371 PF04027.8 AJZ75386.1 - 8.1e-43 145.2 0.0 8.9e-43 145.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF371) HTH_20 PF12840.2 AJZ75387.1 - 2.4e-10 40.0 0.1 3.8e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.15 AJZ75387.1 - 1.8e-06 27.4 0.2 1.3e-05 24.7 0.1 2.1 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family FUR PF01475.14 AJZ75387.1 - 0.00024 21.0 1.1 0.00055 19.8 0.7 1.7 1 1 0 1 1 1 1 Ferric uptake regulator family HTH_12 PF08461.5 AJZ75387.1 - 0.0013 18.3 0.5 0.0045 16.6 0.2 1.9 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain HTH_11 PF08279.7 AJZ75387.1 - 0.0093 15.5 1.8 0.73 9.5 0.1 2.4 2 0 0 2 2 2 1 HTH domain TFIIE_alpha PF02002.12 AJZ75387.1 - 0.05 13.1 0.9 0.58 9.6 0.2 2.2 1 1 1 2 2 2 0 TFIIE alpha subunit DUF2513 PF10711.4 AJZ75387.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) DUF2250 PF10007.4 AJZ75387.1 - 0.12 12.3 2.2 0.22 11.4 0.5 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) SAICAR_synt PF01259.13 AJZ75388.1 - 7.7e-69 231.5 0.1 9.4e-69 231.2 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase DUF3146 PF11344.3 AJZ75388.1 - 0.042 13.2 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) PMT_2 PF13231.1 AJZ75389.1 - 9.3e-15 54.8 17.8 9.3e-15 54.8 12.3 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.13 AJZ75389.1 - 1e-13 51.2 11.6 1e-13 51.2 8.1 2.3 1 1 1 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Glyco_transf_22 PF03901.12 AJZ75389.1 - 0.0002 20.4 12.7 0.0002 20.4 8.8 2.1 1 1 0 2 2 2 2 Alg9-like mannosyltransferase family DUF1729 PF08354.5 AJZ75389.1 - 0.0046 16.7 0.2 0.0091 15.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Peptidase_M50B PF13398.1 AJZ75389.1 - 0.3 10.4 22.6 2.1 7.7 2.6 3.1 2 1 1 3 3 3 0 Peptidase M50B-like DUF4352 PF11611.3 AJZ75391.1 - 0.061 13.4 0.1 0.29 11.2 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4352) DUF4399 PF14347.1 AJZ75391.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) AsnC_trans_reg PF01037.16 AJZ75392.1 - 4.8e-13 48.6 0.2 5.7e-13 48.3 0.2 1.0 1 0 0 1 1 1 1 AsnC family EF1_GNE PF00736.14 AJZ75392.1 - 0.037 13.7 0.1 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain GYD PF08734.6 AJZ75392.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 GYD domain FancD2 PF14631.1 AJZ75392.1 - 0.14 9.2 0.0 0.15 9.1 0.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease GATase_2 PF00310.16 AJZ75393.1 - 4.1e-21 75.0 0.1 5.4e-14 51.6 0.0 3.3 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 AJZ75393.1 - 4.4e-15 55.8 0.0 2.8e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 AJZ75393.1 - 1.3e-13 50.7 0.0 3.7e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 AJZ75393.1 - 4.5e-13 49.0 0.0 1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 AJZ75393.1 - 1.2e-05 24.1 0.0 2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_3 PF15610.1 AJZ75393.1 - 0.043 12.7 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like AIRS_C PF02769.17 AJZ75394.1 - 9.7e-49 165.2 2.9 2.5e-26 92.5 0.2 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 AJZ75394.1 - 6.9e-42 141.6 0.4 3.6e-22 78.4 0.2 2.7 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain Mesothelin PF06060.7 AJZ75394.1 - 0.093 10.7 0.0 0.24 9.3 0.0 1.6 2 0 0 2 2 2 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Nucleoporin_N PF08801.6 AJZ75394.1 - 0.15 10.7 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like Chordopox_RPO7 PF05864.7 AJZ75394.1 - 0.18 11.8 0.7 0.6 10.2 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) GATase_5 PF13507.1 AJZ75395.1 - 1.9e-42 144.9 0.0 5.1e-42 143.5 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.9 AJZ75395.1 - 9.1e-09 35.0 0.0 2.8e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 AJZ75395.1 - 1.8e-08 34.0 0.0 3.3e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 AJZ75395.1 - 6.8e-06 25.6 0.0 9.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 AJZ75395.1 - 0.00094 18.4 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_C26 PF07722.8 AJZ75395.1 - 0.0027 17.1 0.1 0.0073 15.7 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 CBS PF00571.23 AJZ75396.1 - 3.1e-29 100.4 0.8 2.5e-15 55.9 0.0 2.1 2 0 0 2 2 2 2 CBS domain HlyU PF10115.4 AJZ75397.1 - 0.062 13.1 0.2 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Transcriptional activator HlyU TatC PF00902.13 AJZ75398.1 - 6.3e-57 192.4 18.5 7.4e-57 192.2 12.8 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) MttA_Hcf106 PF02416.11 AJZ75399.1 - 8.8e-10 37.5 0.4 1.1e-09 37.2 0.3 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family Polyketide_cyc2 PF10604.4 AJZ75400.1 - 0.0025 17.9 0.0 0.0026 17.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AJZ75400.1 - 0.0065 16.4 0.0 0.0073 16.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.8 AJZ75400.1 - 0.068 12.8 0.0 10 5.7 0.0 2.0 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) Flavoprotein PF02441.14 AJZ75401.1 - 1.3e-27 96.0 0.1 1.7e-27 95.6 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein Bt_P21 PF05560.6 AJZ75401.1 - 0.036 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein HemolysinCabind PF00353.14 AJZ75402.1 - 3.6e-13 48.5 59.4 0.00057 20.0 2.5 8.4 5 1 2 7 7 7 7 Hemolysin-type calcium-binding repeat (2 copies) Calx-beta PF03160.9 AJZ75402.1 - 1.3e-10 41.1 1.0 1.3e-09 37.9 0.0 3.1 2 0 0 2 2 2 1 Calx-beta domain DUF1325 PF07039.6 AJZ75402.1 - 0.14 11.7 3.5 5.3 6.6 0.1 3.7 5 0 0 5 5 5 0 SGF29 tudor-like domain DUF1297 PF06973.7 AJZ75403.1 - 3e-73 245.1 0.1 4.8e-73 244.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.7 AJZ75403.1 - 1.4e-44 150.8 0.0 2.8e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) DNase-RNase PF02577.9 AJZ75404.1 - 7.7e-09 34.8 0.0 8.3e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease DUF4060 PF13269.1 AJZ75404.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4060) UPF0150 PF03681.10 AJZ75405.1 - 6.2e-07 28.9 0.0 7.8e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0150) DUF3832 PF12909.2 AJZ75405.1 - 6.2e-05 22.9 0.0 7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3832) ATP-synt_D PF01813.12 AJZ75405.1 - 0.015 14.8 0.1 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 ATP synthase subunit D YcfA PF07927.7 AJZ75406.1 - 1.6e-07 31.0 0.1 2.2e-07 30.6 0.1 1.3 1 1 0 1 1 1 1 YcfA-like protein PrgI PF12666.2 AJZ75407.1 - 0.014 15.5 0.1 0.014 15.5 0.1 3.6 3 1 0 3 3 3 0 PrgI family protein Mut7-C PF01927.11 AJZ75409.1 - 0.00031 20.7 0.0 0.00032 20.6 0.0 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain IPT PF01745.11 AJZ75410.1 - 0.0018 17.5 0.1 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase DUF460 PF04312.8 AJZ75410.1 - 0.063 12.8 1.0 0.21 11.0 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF460) Methyltransf_3 PF01596.12 AJZ75411.1 - 1.3e-28 99.4 0.3 1.6e-28 99.1 0.2 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 AJZ75411.1 - 1.2e-14 55.0 0.0 1.7e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJZ75411.1 - 3.2e-07 30.8 0.0 4.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 AJZ75411.1 - 2.5e-06 26.9 0.0 3.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_26 PF13659.1 AJZ75411.1 - 0.00094 19.1 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 AJZ75411.1 - 0.0024 17.4 0.0 0.0057 16.2 0.0 1.5 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase zf-RAG1 PF10426.4 AJZ75411.1 - 0.047 13.6 0.3 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain PCMT PF01135.14 AJZ75411.1 - 0.093 12.2 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 AJZ75411.1 - 0.13 11.6 0.1 0.34 10.2 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 CPDase PF07823.6 AJZ75413.1 - 1.3e-15 57.4 1.1 4.8e-15 55.5 0.8 1.9 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 AJZ75413.1 - 0.038 13.7 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily DUF4437 PF14499.1 AJZ75414.1 - 0.01 14.7 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) DUF1971 PF09313.6 AJZ75414.1 - 0.041 13.6 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) PMSR PF01625.16 AJZ75415.1 - 3.2e-63 212.2 0.6 3.8e-63 212.0 0.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Cmc1 PF08583.5 AJZ75417.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Peptidase_M10 PF00413.19 AJZ75418.1 - 1.1e-12 47.9 0.0 2.4e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 AJZ75418.1 - 0.0012 18.2 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_5 PF13688.1 AJZ75418.1 - 0.011 15.7 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.19 AJZ75418.1 - 0.026 13.9 0.0 0.071 12.4 0.0 1.7 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.1 AJZ75418.1 - 0.027 14.5 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3887 PF13026.1 AJZ75418.1 - 0.09 13.0 2.0 2.4 8.5 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3887) Musclin PF11037.3 AJZ75418.1 - 0.13 11.8 0.5 0.24 11.0 0.3 1.5 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Osteoregulin PF07175.6 AJZ75419.1 - 0.028 14.2 0.3 0.037 13.8 0.2 1.1 1 0 0 1 1 1 0 Osteoregulin Cupin_2 PF07883.6 AJZ75420.1 - 2.1e-07 30.3 0.0 1.1e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 AJZ75420.1 - 4.5e-05 22.9 0.0 5.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Cupin Auxin_BP PF02041.11 AJZ75420.1 - 0.0006 19.2 0.1 0.00072 19.0 0.1 1.2 1 0 0 1 1 1 1 Auxin binding protein Cupin_8 PF13621.1 AJZ75420.1 - 0.00075 19.0 0.6 0.0045 16.5 0.3 1.9 1 1 0 1 1 1 1 Cupin-like domain AraC_binding PF02311.14 AJZ75420.1 - 0.0022 17.6 0.0 0.0057 16.3 0.0 1.7 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_4 PF08007.7 AJZ75420.1 - 0.018 14.3 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Cupin superfamily protein zf-C3HC4_4 PF15227.1 AJZ75421.1 - 0.0034 17.2 2.0 0.035 13.9 0.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AJZ75421.1 - 0.015 14.9 1.5 0.56 9.9 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AJZ75421.1 - 0.039 13.9 2.2 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AJZ75421.1 - 0.053 13.2 2.5 4.7 7.0 0.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 AJZ75421.1 - 0.3 10.9 1.6 9.7 6.1 0.1 2.2 2 0 0 2 2 2 0 Ring finger domain DUF2602 PF10782.4 AJZ75421.1 - 0.52 10.1 5.1 9.2 6.1 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2602) TPR_7 PF13176.1 AJZ75422.1 - 0.029 14.1 0.0 4.2 7.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2602 PF10782.4 AJZ75424.1 - 0.0095 15.7 0.8 0.0095 15.7 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2602) SopA PF13981.1 AJZ75424.1 - 0.021 14.8 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 SopA-like central domain Metallothio_Pro PF02069.11 AJZ75424.1 - 0.069 12.9 1.8 0.069 12.9 1.3 1.7 2 0 0 2 2 2 0 Prokaryotic metallothionein DCR PF14047.1 AJZ75424.1 - 0.23 11.7 0.1 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 Dppa2/4 conserved region GTP_EFTU PF00009.22 AJZ75426.1 - 4.5e-52 176.2 0.1 7.3e-52 175.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AJZ75426.1 - 1.3e-29 102.1 0.1 7.4e-29 99.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 AJZ75426.1 - 6.7e-20 70.7 0.0 2.3e-19 69.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 AJZ75426.1 - 1.7e-18 66.1 0.1 4e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 AJZ75426.1 - 1.2e-14 54.1 0.0 3.8e-14 52.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SIS PF01380.17 AJZ75427.1 - 3.1e-08 33.2 2.3 7.1e-05 22.4 0.0 2.6 3 0 0 3 3 3 2 SIS domain SIS_2 PF13580.1 AJZ75427.1 - 0.017 14.8 2.4 0.73 9.5 0.0 3.1 2 1 1 3 3 3 0 SIS domain CBS PF00571.23 AJZ75428.1 - 1.5e-37 127.1 1.5 7.7e-12 44.8 0.1 4.1 4 0 0 4 4 4 4 CBS domain RTP PF02334.11 AJZ75428.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Replication terminator protein VitK2_biosynth PF02621.9 AJZ75429.1 - 5.1e-67 225.7 0.0 5.7e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis DUF77 PF01910.12 AJZ75430.1 - 6.1e-25 86.7 0.1 6.9e-25 86.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Radical_SAM PF04055.16 AJZ75431.1 - 1.1e-17 64.7 0.0 2.5e-17 63.5 0.0 1.6 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 AJZ75431.1 - 0.001 19.1 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AJZ75431.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF849 PF05853.7 AJZ75431.1 - 0.038 12.8 0.0 0.71 8.6 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic protein of unknown function (DUF849) DUF3584 PF12128.3 AJZ75433.1 - 0.84 6.8 47.0 1.1 6.4 32.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Apolipoprotein PF01442.13 AJZ75434.1 - 0.017 14.6 17.5 0.024 14.1 12.1 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Asp-B-Hydro_N PF05279.6 AJZ75434.1 - 0.099 12.4 22.2 0.12 12.1 15.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Exonuc_VII_L PF02601.10 AJZ75434.1 - 0.11 11.6 10.5 0.13 11.4 7.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ARGLU PF15346.1 AJZ75434.1 - 5.9 6.6 31.8 20 4.9 10.9 2.3 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 DUF572 PF04502.8 AJZ75434.1 - 7.7 5.6 25.8 9.5 5.3 17.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2884 PF11101.3 AJZ75434.1 - 8.5 5.6 16.7 16 4.7 11.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) TPR_11 PF13414.1 AJZ75435.1 - 6.4e-25 86.6 13.8 5.5e-12 45.1 0.8 3.2 1 1 3 4 4 4 4 TPR repeat TPR_1 PF00515.23 AJZ75435.1 - 6.5e-19 66.6 3.3 2.9e-07 29.8 0.7 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 AJZ75435.1 - 2.8e-16 58.0 1.5 5e-05 22.9 0.3 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 AJZ75435.1 - 6e-16 58.6 0.0 4e-08 33.7 0.1 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ75435.1 - 2.6e-13 50.0 0.1 0.00011 22.4 0.2 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 AJZ75435.1 - 3.8e-12 45.7 0.0 0.023 15.3 0.0 4.4 2 2 3 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJZ75435.1 - 2e-10 40.4 0.9 0.079 12.8 0.0 4.2 3 1 1 4 4 4 3 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 AJZ75435.1 - 3.9e-10 39.5 2.2 6.8e-05 22.7 0.4 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 AJZ75435.1 - 1.8e-08 33.8 3.0 1.8e-05 24.5 0.2 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 AJZ75435.1 - 1.4e-07 30.7 0.4 0.083 12.7 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ75435.1 - 3.4e-07 29.5 2.9 0.006 16.2 0.3 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 AJZ75435.1 - 3.6e-07 30.2 0.0 1.5 9.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 AJZ75435.1 - 1.5e-05 25.0 5.0 0.0091 16.1 0.3 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AJZ75435.1 - 3e-05 23.7 0.0 0.05 13.4 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat NARP1 PF12569.3 AJZ75435.1 - 0.011 14.5 1.7 0.66 8.6 0.0 2.4 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 M11L PF11099.3 AJZ75435.1 - 0.019 14.6 0.8 0.031 14.0 0.2 1.6 1 1 0 1 1 1 0 Apoptosis regulator M11L like TPR_10 PF13374.1 AJZ75435.1 - 0.047 13.6 0.2 3.5 7.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.5 AJZ75435.1 - 0.085 11.7 0.3 0.12 11.2 0.2 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Alkyl_sulf_dimr PF14863.1 AJZ75435.1 - 0.12 12.6 0.3 6.2 7.0 0.1 2.7 1 1 1 3 3 3 0 Alkyl sulfatase dimerisation MIT PF04212.13 AJZ75435.1 - 0.31 10.9 1.8 27 4.7 0.1 3.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Mu-like_Com PF10122.4 AJZ75436.1 - 0.075 12.0 0.2 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Mu-like prophage protein Com Malic_M PF03949.10 AJZ75437.1 - 6.7e-54 183.1 2.6 9.2e-54 182.6 1.8 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 AJZ75437.1 - 2.9e-22 79.1 0.3 1.1e-19 70.7 0.2 2.6 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain AdoHcyase_NAD PF00670.16 AJZ75437.1 - 0.00014 21.7 2.5 0.0025 17.6 0.7 2.8 2 1 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.16 AJZ75437.1 - 0.0008 19.0 1.6 0.0013 18.3 0.6 1.7 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.16 AJZ75437.1 - 0.0058 16.4 0.7 0.019 14.7 0.6 1.8 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 AJZ75437.1 - 0.0081 16.2 0.2 0.024 14.7 0.1 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Phage_int_SAM_3 PF14659.1 AJZ75437.1 - 0.036 14.3 2.7 2.1 8.6 0.1 3.3 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Pyr_redox_2 PF07992.9 AJZ75437.1 - 0.055 13.3 0.2 0.095 12.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 AJZ75437.1 - 0.07 12.7 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPR_1 PF00515.23 AJZ75438.1 - 2.1e-21 74.5 0.2 9.6e-13 47.1 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 AJZ75438.1 - 9.7e-20 68.8 0.2 1.8e-10 39.9 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 AJZ75438.1 - 1.5e-17 63.0 0.1 1.8e-17 62.7 0.1 1.0 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 AJZ75438.1 - 3.7e-14 52.9 0.4 1.1e-13 51.3 0.2 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ75438.1 - 1.4e-13 49.5 0.2 1.3e-08 34.0 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ75438.1 - 6.8e-13 48.7 0.1 7.6e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 AJZ75438.1 - 2.2e-11 42.6 0.2 1.3e-05 24.5 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 AJZ75438.1 - 2.4e-11 43.2 0.2 1.5e-05 25.2 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ75438.1 - 2.6e-11 43.2 0.3 2.1e-10 40.3 0.2 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 AJZ75438.1 - 1.4e-09 37.3 0.2 4.4e-07 29.5 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 AJZ75438.1 - 9.8e-09 34.9 0.1 1.1e-08 34.7 0.1 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJZ75438.1 - 2.8e-06 27.0 0.0 0.071 12.9 0.0 2.1 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 AJZ75438.1 - 1.1e-05 25.5 0.1 0.064 13.7 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 AJZ75438.1 - 0.00011 22.0 0.1 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.3 AJZ75438.1 - 0.00017 20.5 0.0 0.0002 20.2 0.0 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_3 PF07720.7 AJZ75438.1 - 0.0004 20.1 0.1 0.22 11.3 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.2 AJZ75438.1 - 0.0012 18.6 0.0 0.0016 18.2 0.0 1.2 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) Apc3 PF12895.2 AJZ75438.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 EST1_DNA_bind PF10373.4 AJZ75438.1 - 0.0013 17.9 0.0 0.0014 17.9 0.0 1.0 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain TPR_15 PF13429.1 AJZ75438.1 - 0.0022 17.1 0.0 0.15 11.0 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TOM20_plant PF06552.7 AJZ75438.1 - 0.0053 16.3 0.0 0.026 14.1 0.0 1.8 1 1 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 PPR PF01535.15 AJZ75438.1 - 0.0054 16.6 0.1 2.1 8.4 0.0 2.4 2 1 0 2 2 2 1 PPR repeat BTAD PF03704.12 AJZ75438.1 - 0.0054 17.0 0.0 0.0063 16.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial transcriptional activator domain MIT PF04212.13 AJZ75438.1 - 0.0084 15.9 0.1 0.34 10.8 0.0 2.1 1 1 1 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_5 PF12688.2 AJZ75438.1 - 0.0099 15.9 0.0 0.02 14.9 0.0 1.5 1 1 0 1 1 1 1 Tetratrico peptide repeat SHNi-TPR PF10516.4 AJZ75438.1 - 0.058 12.6 0.3 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 SHNi-TPR PPTA PF01239.17 AJZ75438.1 - 0.11 11.9 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat DUF1250 PF06855.7 AJZ75438.1 - 0.13 11.8 0.1 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) Response_reg PF00072.19 AJZ75439.1 - 1.3e-12 47.6 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain AsnC_trans_reg PF01037.16 AJZ75440.1 - 1.9e-12 46.7 0.2 2.7e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 AsnC family HTH_AsnC-type PF13404.1 AJZ75440.1 - 6.2e-11 41.6 0.6 9.3e-11 41.0 0.4 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 AJZ75440.1 - 1e-10 40.7 1.8 1.9e-10 39.9 1.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 AJZ75440.1 - 0.00022 20.7 0.4 0.00056 19.4 0.3 1.8 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.1 AJZ75440.1 - 0.0055 16.4 0.2 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_10 PF04967.7 AJZ75440.1 - 0.045 13.3 0.1 0.08 12.5 0.1 1.4 1 0 0 1 1 1 0 HTH DNA binding domain MarR PF01047.17 AJZ75440.1 - 0.13 12.0 0.8 0.21 11.3 0.2 1.6 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.1 AJZ75440.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HD PF01966.17 AJZ75441.1 - 0.0015 18.5 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 HD domain Sugar_tr PF00083.19 AJZ75442.1 - 2.4e-35 121.9 36.8 8.5e-29 100.4 6.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 AJZ75442.1 - 1e-32 113.2 37.2 1e-32 113.2 25.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 AJZ75442.1 - 1.2e-06 27.2 28.8 0.0001 20.8 13.4 2.9 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 AJZ75442.1 - 8.4e-06 25.4 3.6 0.0004 20.1 0.3 3.3 2 0 0 2 2 2 1 MFS_1 like family ATG22 PF11700.3 AJZ75442.1 - 1.1e-05 24.1 14.3 1.1e-05 24.1 9.9 2.7 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like DUF791 PF05631.9 AJZ75442.1 - 2.4e-05 23.2 1.3 2.4e-05 23.2 0.9 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF791) UTP15_C PF09384.5 AJZ75443.1 - 0.086 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 UTP15 C terminal PAC2 PF09754.4 AJZ75444.1 - 1.2e-17 64.5 0.0 1.6e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 PAC2 family CarboxypepD_reg PF13620.1 AJZ75446.1 - 1.9e-07 31.0 1.2 3.7e-07 30.1 0.8 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 AJZ75446.1 - 0.00058 19.8 0.6 0.0019 18.2 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Atg14 PF10186.4 AJZ75446.1 - 3.3 6.5 8.3 0.36 9.7 0.5 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 YbaJ PF10757.4 AJZ75447.1 - 0.07 13.2 0.0 0.076 13.1 0.0 1.1 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ DUF4131 PF13567.1 AJZ75448.1 - 0.17 11.3 1.5 0.15 11.4 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) S4 PF01479.20 AJZ75449.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 S4 domain HTH_45 PF14947.1 AJZ75450.1 - 0.00054 19.7 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.14 AJZ75450.1 - 0.008 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PadR PF03551.9 AJZ75450.1 - 0.0098 15.6 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.1 AJZ75450.1 - 0.024 14.6 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HxlR PF01638.12 AJZ75450.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DNA_pol3_a_NI PF14480.1 AJZ75451.1 - 0.059 13.0 0.3 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I Nucleoside_tran PF01733.13 AJZ75451.1 - 0.092 11.8 0.6 0.53 9.3 0.1 1.9 1 1 0 2 2 2 0 Nucleoside transporter PIN PF01850.16 AJZ75452.1 - 8.6e-11 42.2 0.0 1.2e-10 41.7 0.0 1.2 1 1 0 1 1 1 1 PIN domain PIN_4 PF13638.1 AJZ75452.1 - 0.00011 22.2 0.0 0.0003 20.8 0.0 1.7 1 1 0 1 1 1 1 PIN domain DUF4411 PF14367.1 AJZ75452.1 - 0.012 15.3 0.1 0.094 12.4 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) PIN_3 PF13470.1 AJZ75452.1 - 0.058 14.0 0.0 0.11 13.2 0.0 1.5 1 1 0 1 1 1 0 PIN domain IF-2 PF11987.3 AJZ75452.1 - 0.059 13.2 0.1 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Translation-initiation factor 2 Response_reg PF00072.19 AJZ75453.1 - 0.01 15.8 0.1 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Response regulator receiver domain BPD_transp_1 PF00528.17 AJZ75454.1 - 1.8e-35 122.1 17.6 1.8e-35 122.1 12.2 2.0 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component Gly-zipper_Omp PF13488.1 AJZ75454.1 - 0.23 11.1 1.5 0.48 10.1 0.1 2.2 2 0 0 2 2 2 0 Glycine zipper BPD_transp_1 PF00528.17 AJZ75455.1 - 4.7e-26 91.4 6.9 4.7e-26 91.4 4.8 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Phage_int_SAM_4 PF13495.1 AJZ75456.1 - 0.12 12.7 0.4 0.51 10.6 0.1 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain AAA_13 PF13166.1 AJZ75457.1 - 0.00032 19.3 40.1 0.012 14.1 10.1 2.1 1 1 1 2 2 2 2 AAA domain Baculo_PEP_C PF04513.7 AJZ75457.1 - 0.22 11.3 13.7 0.62 9.8 0.3 4.4 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.16 AJZ75457.1 - 0.42 10.1 27.6 0.45 10.0 4.1 3.7 2 1 2 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Exonuc_VII_S PF02609.11 AJZ75457.1 - 1.2 8.9 6.9 5.3 6.8 0.1 3.9 3 0 0 3 3 3 0 Exonuclease VII small subunit NPV_P10 PF05531.7 AJZ75457.1 - 2.3 8.5 25.9 7.5 6.8 1.7 5.9 4 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein RPM2 PF08579.6 AJZ75457.1 - 5.6 7.1 22.2 1.8 8.7 2.4 4.0 3 2 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) Polyketide_cyc2 PF10604.4 AJZ75458.1 - 2e-10 40.9 0.0 2.3e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polysacc_deac_1 PF01522.16 AJZ75459.1 - 1.9e-25 88.8 0.0 6.3e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 AJZ75459.1 - 3.3e-08 32.8 0.0 2.1e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolase family 57 CarboxypepD_reg PF13620.1 AJZ75459.1 - 3e-05 24.0 0.7 0.78 9.8 0.0 3.8 3 1 0 3 3 3 2 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 AJZ75459.1 - 0.0012 18.5 5.3 0.14 11.8 1.1 4.0 3 1 0 3 3 3 2 Cna protein B-type domain DUF4480 PF13715.1 AJZ75459.1 - 0.0078 16.2 3.3 2.2 8.4 0.0 3.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4480) PAN_2 PF08276.6 AJZ75459.1 - 0.02 14.7 0.2 3 7.7 0.0 2.5 2 0 0 2 2 2 0 PAN-like domain DUF1664 PF07889.7 AJZ75460.1 - 0.96 9.2 15.8 0.18 11.6 4.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YkuI_C PF10388.4 AJZ75460.1 - 1 9.0 15.9 0.18 11.5 3.9 2.5 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain DUF651 PF04895.7 AJZ75460.1 - 3.4 7.3 5.8 3.9 7.1 0.1 2.9 2 1 1 3 3 3 0 Archaeal protein of unknown function (DUF651) SlyX PF04102.7 AJZ75460.1 - 4.8 7.6 11.5 0.44 10.9 4.2 2.1 2 1 0 2 2 2 0 SlyX ZYG-11_interact PF05884.7 AJZ75460.1 - 8.5 5.3 7.2 4.3 6.3 1.9 2.0 2 0 0 2 2 2 0 Interactor of ZYG-11 IncA PF04156.9 AJZ75460.1 - 8.9 5.8 20.5 20 4.6 14.2 1.6 1 1 0 1 1 1 0 IncA protein DUF745 PF05335.8 AJZ75460.1 - 9.5 5.6 12.3 2.4 7.6 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) NPV_P10 PF05531.7 AJZ75460.1 - 9.6 6.5 8.8 23 5.3 1.2 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ParBc PF02195.13 AJZ75461.1 - 1e-18 67.2 0.1 2e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_7 PF02796.10 AJZ75461.1 - 0.027 14.3 0.0 0.11 12.3 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Phage_int_SAM_1 PF02899.12 AJZ75461.1 - 5.1 7.3 9.8 1.6 8.9 0.2 3.9 3 2 1 4 4 4 0 Phage integrase, N-terminal SAM-like domain XPG_I PF00867.13 AJZ75462.1 - 1.3e-25 89.2 0.0 2.4e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AJZ75462.1 - 2.8e-20 72.4 0.0 7.5e-20 71.0 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 AJZ75462.1 - 1.9e-05 24.8 0.0 4.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Bul1_C PF04426.7 AJZ75463.1 - 0.0083 15.3 0.3 0.013 14.7 0.1 1.3 1 1 0 1 1 1 1 Bul1 C terminus Pox_I5 PF04713.7 AJZ75463.1 - 0.021 14.5 0.4 0.031 13.9 0.3 1.2 1 0 0 1 1 1 0 Poxvirus protein I5 Ly49 PF08391.5 AJZ75463.1 - 0.049 13.7 0.4 0.059 13.5 0.3 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region IgaA PF07095.6 AJZ75463.1 - 0.057 11.1 0.9 0.06 11.1 0.6 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA TrbC PF04956.8 AJZ75463.1 - 0.093 12.7 0.2 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family DUF106 PF01956.11 AJZ75463.1 - 0.27 10.7 1.7 0.36 10.3 1.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 EntA_Immun PF08951.5 AJZ75463.1 - 0.32 11.1 3.2 4 7.6 0.6 2.3 1 1 1 2 2 2 0 Enterocin A Immunity Lumazine_bd PF12870.2 AJZ75463.1 - 0.41 10.7 6.2 0.5 10.4 4.3 1.1 1 0 0 1 1 1 0 Lumazine-binding domain PEP-utilisers_N PF05524.8 AJZ75463.1 - 1.1 9.0 8.5 1.8 8.4 4.2 1.9 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Toxin_43 PF15604.1 AJZ75463.1 - 3.7 7.5 8.6 6 6.9 6.0 1.4 1 1 0 1 1 1 0 Putative toxin 43 YbaB_DNA_bd PF02575.11 AJZ75463.1 - 4.6 7.1 9.4 0.18 11.7 0.9 2.3 1 1 1 2 2 2 0 YbaB/EbfC DNA-binding family RecR PF02132.10 AJZ75464.1 - 0.011 15.1 1.0 0.08 12.3 0.7 1.9 2 0 0 2 2 2 0 RecR protein zf-RanBP PF00641.13 AJZ75464.1 - 8.4 5.5 6.5 83 2.4 4.5 2.0 1 1 0 1 1 1 0 Zn-finger in Ran binding protein and others AMP-binding PF00501.23 AJZ75465.1 - 2.9e-96 322.4 0.0 3.8e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AJZ75465.1 - 4.2e-19 69.2 0.0 8e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PRC PF05239.11 AJZ75466.1 - 0.011 15.5 1.8 0.025 14.4 1.3 1.5 1 0 0 1 1 1 0 PRC-barrel domain Pox_I1 PF03289.8 AJZ75466.1 - 0.025 13.3 2.6 0.035 12.9 1.8 1.1 1 0 0 1 1 1 0 Poxvirus protein I1 MerR-DNA-bind PF09278.6 AJZ75466.1 - 0.043 14.2 3.7 4.2 7.8 0.0 2.6 1 1 1 2 2 2 0 MerR, DNA binding DUF2203 PF09969.4 AJZ75466.1 - 0.31 11.2 2.6 0.5 10.6 0.4 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Thy1 PF02511.10 AJZ75467.1 - 1.4e-30 106.1 1.3 1.3e-18 67.0 0.6 2.4 2 0 0 2 2 2 2 Thymidylate synthase complementing protein DUF3510 PF12022.3 AJZ75467.1 - 0.039 14.0 0.2 0.039 14.0 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) SelR PF01641.13 AJZ75468.1 - 5.6e-52 174.6 0.3 6.6e-52 174.4 0.2 1.0 1 0 0 1 1 1 1 SelR domain DUF2437 PF10370.4 AJZ75468.1 - 0.009 16.3 0.0 0.024 15.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2437) Yippee-Mis18 PF03226.9 AJZ75468.1 - 0.041 13.9 1.5 0.15 12.0 1.1 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Desulfoferrod_N PF06397.7 AJZ75468.1 - 0.052 12.9 1.3 0.098 12.0 0.9 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain DZR PF12773.2 AJZ75468.1 - 0.12 12.1 3.2 0.88 9.4 2.2 2.4 1 1 0 1 1 1 0 Double zinc ribbon HECT_2 PF09814.4 AJZ75468.1 - 0.18 10.4 0.9 0.24 10.1 0.0 1.6 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF2318 PF10080.4 AJZ75468.1 - 0.31 10.8 3.1 2 8.2 0.3 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Zn_ribbon_recom PF13408.1 AJZ75468.1 - 1.6 9.0 6.6 9.1 6.6 4.4 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Homoserine_dh PF00742.14 AJZ75469.1 - 2.2e-54 183.8 0.2 3.5e-54 183.1 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase ELFV_dehydrog PF00208.16 AJZ75469.1 - 2.6e-05 23.9 0.1 6.8e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_3 PF03447.11 AJZ75469.1 - 3.2e-05 24.2 0.0 9.5e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PUA PF01472.15 AJZ75470.1 - 5.3e-19 67.7 0.2 8.1e-19 67.1 0.2 1.3 1 0 0 1 1 1 1 PUA domain RelA_SpoT PF04607.12 AJZ75472.1 - 5.8e-22 77.8 0.1 5.8e-22 77.8 0.1 2.0 3 0 0 3 3 3 1 Region found in RelA / SpoT proteins ArsB PF02040.10 AJZ75472.1 - 0.14 11.1 0.3 0.19 10.6 0.2 1.1 1 0 0 1 1 1 0 Arsenical pump membrane protein Peptidase_M20 PF01546.23 AJZ75473.1 - 3.3e-30 105.0 0.0 4.4e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AJZ75473.1 - 1.9e-16 59.7 0.0 3.2e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain WG_beta_rep PF14903.1 AJZ75473.1 - 0.032 14.4 0.0 0.49 10.7 0.0 2.5 2 0 0 2 2 2 0 WG containing repeat Nuc_deoxyrib_tr PF05014.10 AJZ75473.1 - 0.033 14.0 0.0 0.52 10.2 0.0 2.6 3 0 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase Carb_kinase PF01256.12 AJZ75474.1 - 3.9e-48 163.8 2.8 4.6e-48 163.6 2.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 AJZ75474.1 - 1.6e-09 37.3 0.1 2.5e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 AJZ75474.1 - 6.5e-06 25.5 0.1 9.4e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Interferon PF00143.14 AJZ75475.1 - 0.094 12.5 8.1 0.041 13.7 3.8 1.7 1 1 0 1 1 1 0 Interferon alpha/beta domain PEP-utilisers_N PF05524.8 AJZ75475.1 - 0.31 10.8 5.1 0.73 9.6 3.5 1.8 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF2175 PF09943.4 AJZ75475.1 - 0.33 11.0 17.6 0.29 11.2 2.9 3.2 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Phage_pRha PF09669.5 AJZ75475.1 - 0.93 9.8 0.1 0.93 9.8 0.0 2.7 2 1 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Occludin_ELL PF07303.8 AJZ75475.1 - 2.1 9.1 10.5 0.94 10.2 5.0 2.0 1 1 0 1 1 1 0 Occludin homology domain Vps39_2 PF10367.4 AJZ75475.1 - 3 8.0 5.8 1.9 8.6 2.2 2.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 ZapA PF05164.8 AJZ75475.1 - 5 7.1 9.2 17 5.4 3.3 3.4 1 1 1 3 3 3 0 Cell division protein ZapA GCD14 PF08704.5 AJZ75476.1 - 8e-32 110.6 0.0 1.3e-31 110.0 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 AJZ75476.1 - 5.9e-11 42.1 0.0 9e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AJZ75476.1 - 3.7e-08 33.1 0.0 5.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 AJZ75476.1 - 3e-07 31.2 0.0 6.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJZ75476.1 - 3.3e-07 30.8 0.0 6.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AJZ75476.1 - 1.5e-06 27.4 0.0 2.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AJZ75476.1 - 4.2e-06 26.7 0.0 1.5e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 AJZ75476.1 - 6.6e-06 25.3 0.0 9e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 AJZ75476.1 - 3.8e-05 24.1 0.0 0.00027 21.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 AJZ75476.1 - 0.0005 19.1 0.0 0.00079 18.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 AJZ75476.1 - 0.00056 19.1 0.0 0.00077 18.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 AJZ75476.1 - 0.0022 18.2 0.0 0.0053 17.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AJZ75476.1 - 0.0024 17.2 0.0 0.0053 16.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 AJZ75476.1 - 0.005 17.2 0.0 0.016 15.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 AJZ75476.1 - 0.0097 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 AJZ75476.1 - 0.011 15.6 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 AJZ75476.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.12 AJZ75476.1 - 0.026 13.4 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin UPF0020 PF01170.13 AJZ75476.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 GCD14_N PF14801.1 AJZ75476.1 - 0.11 12.0 0.2 3.5 7.2 0.0 2.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_23 PF13489.1 AJZ75476.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Response_reg PF00072.19 AJZ75477.1 - 3.1e-16 59.3 0.2 5.3e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain DUF1487 PF07368.6 AJZ75477.1 - 0.0039 16.4 0.4 0.0076 15.5 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Ead_Ea22 PF13935.1 AJZ75477.1 - 0.013 15.8 0.7 0.015 15.5 0.5 1.4 1 1 0 1 1 1 0 Ead/Ea22-like protein FleQ PF06490.6 AJZ75477.1 - 0.032 14.3 0.5 0.071 13.2 0.3 1.6 1 1 0 1 1 1 0 Flagellar regulatory protein FleQ DUF1086 PF06461.6 AJZ75477.1 - 0.082 12.6 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) tRNA-synt_1d PF00750.14 AJZ75478.1 - 6.6e-37 127.1 2.9 7e-29 100.7 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 AJZ75478.1 - 5.8e-27 94.0 0.1 5.8e-27 94.0 0.1 2.2 3 0 0 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 AJZ75478.1 - 3.2e-13 50.0 0.1 1.2e-12 48.1 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 AJZ75478.1 - 0.00033 19.8 0.0 0.00074 18.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Phytoreo_S7 PF07236.6 AJZ75478.1 - 0.021 13.1 0.5 0.15 10.3 0.1 2.0 2 0 0 2 2 2 0 Phytoreovirus S7 protein tRNA-synt_1g PF09334.6 AJZ75478.1 - 0.032 12.9 0.5 0.075 11.6 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (M) TGS PF02824.16 AJZ75479.1 - 4.8e-22 77.5 0.0 8.6e-22 76.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AJZ75479.1 - 5.7e-21 74.6 0.0 1.6e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AJZ75479.1 - 6.1e-15 54.8 1.0 8.8e-14 51.0 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 AJZ75479.1 - 0.00022 20.5 0.5 0.016 14.4 0.0 2.5 1 1 1 2 2 2 1 ADP-ribosylation factor family AIG1 PF04548.11 AJZ75479.1 - 0.00043 19.4 0.1 0.001 18.2 0.0 1.6 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 AJZ75479.1 - 0.00046 20.0 4.7 0.067 13.0 0.3 2.9 3 1 1 4 4 4 2 Dynamin family DUF258 PF03193.11 AJZ75479.1 - 0.0024 17.1 0.1 0.005 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 AJZ75479.1 - 0.0031 17.9 0.0 0.0093 16.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 AJZ75479.1 - 0.0093 15.1 0.6 0.021 14.0 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 AJZ75479.1 - 0.022 13.5 0.1 0.1 11.3 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_28 PF13521.1 AJZ75479.1 - 0.032 14.2 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Acetyltransf_7 PF13508.1 AJZ75479.1 - 0.054 13.6 0.1 21 5.3 0.0 2.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain cobW PF02492.14 AJZ75479.1 - 0.064 12.6 4.8 0.77 9.1 0.5 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 AJZ75479.1 - 0.091 12.6 0.1 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 AJZ75479.1 - 0.1 11.9 1.4 6.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Ras family Collagen PF01391.13 AJZ75482.1 - 1.2e-60 200.8 230.8 6.4e-10 38.4 22.5 7.2 1 1 4 5 5 5 4 Collagen triple helix repeat (20 copies) TPR_2 PF07719.12 AJZ75483.1 - 1.4e-20 71.4 0.0 2.6e-05 23.7 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 AJZ75483.1 - 8.1e-20 70.2 0.1 5.8e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AJZ75483.1 - 1.2e-17 62.6 0.2 0.0022 17.5 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 AJZ75483.1 - 1.8e-17 63.5 0.0 3.1e-08 34.0 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ75483.1 - 5.8e-12 45.7 0.2 2.4e-06 27.8 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 AJZ75483.1 - 8.4e-12 44.3 0.5 0.0069 16.4 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ75483.1 - 2e-09 37.2 2.2 0.00072 19.4 0.2 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 AJZ75483.1 - 2.3e-09 37.0 0.0 0.019 15.5 0.0 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ75483.1 - 8.8e-09 34.5 3.5 0.0025 17.4 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJZ75483.1 - 1.1e-07 31.5 0.0 0.022 14.6 0.0 4.0 1 1 2 3 3 3 3 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 AJZ75483.1 - 3.6e-07 29.9 0.3 0.00027 20.7 0.0 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat Apc3 PF12895.2 AJZ75483.1 - 5.4e-07 29.6 5.5 8e-05 22.6 0.3 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AJZ75483.1 - 2.5e-06 27.5 1.2 0.0087 16.4 0.1 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat YfiO PF13525.1 AJZ75483.1 - 0.00011 21.6 0.6 0.065 12.6 0.0 2.5 3 0 0 3 3 3 2 Outer membrane lipoprotein HTH_27 PF13463.1 AJZ75483.1 - 0.0024 18.1 0.1 0.014 15.7 0.0 2.2 1 1 1 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.14 AJZ75483.1 - 0.0034 17.0 0.1 0.67 9.7 0.1 2.8 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB TPR_18 PF13512.1 AJZ75483.1 - 0.033 14.2 1.1 4.8 7.1 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 AJZ75483.1 - 0.12 12.2 0.6 13 5.8 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Mg-por_mtran_C PF07109.6 AJZ75483.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 Magnesium-protoporphyrin IX methyltransferase C-terminus Rhodanese PF00581.15 AJZ75484.1 - 2.4e-40 137.4 0.1 3.9e-19 69.0 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain TFIIIC_sub6 PF10419.4 AJZ75484.1 - 0.16 11.4 0.7 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 TFIIIC subunit NIR_SIR PF01077.17 AJZ75485.1 - 1.3e-38 131.8 0.0 1.5e-28 99.1 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 AJZ75485.1 - 8.7e-36 121.3 0.0 4.6e-17 61.4 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Thi4 PF01946.12 AJZ75486.1 - 1.2e-64 217.5 0.1 1.5e-64 217.2 0.1 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 AJZ75486.1 - 1.4e-11 43.9 0.0 2.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 AJZ75486.1 - 5e-09 35.7 0.0 7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AJZ75486.1 - 4.8e-08 32.9 0.1 9.1e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AJZ75486.1 - 4.1e-07 29.2 0.4 5.7e-05 22.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AJZ75486.1 - 6.1e-07 28.8 0.1 9.4e-07 28.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AJZ75486.1 - 2e-06 27.8 0.2 3.4e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AJZ75486.1 - 5.4e-06 25.1 0.1 8e-06 24.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 AJZ75486.1 - 7.8e-05 21.7 0.2 0.0078 15.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 AJZ75486.1 - 0.00026 21.0 0.2 0.00049 20.2 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AJZ75486.1 - 0.00084 18.2 0.2 0.0016 17.4 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 AJZ75486.1 - 0.033 12.8 0.1 5.7 5.4 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.22 AJZ75486.1 - 0.055 13.8 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 AJZ75486.1 - 0.064 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 AJZ75486.1 - 0.087 12.6 0.3 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding GDI PF00996.13 AJZ75486.1 - 0.17 10.1 0.1 0.26 9.5 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox_2 PF07992.9 AJZ75488.1 - 1.3e-34 119.8 0.3 6.4e-34 117.5 0.2 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AJZ75488.1 - 4.5e-18 65.4 1.2 3.9e-17 62.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AJZ75488.1 - 5.7e-15 55.9 0.3 7.7e-13 48.9 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AJZ75488.1 - 5.2e-08 32.1 3.1 0.00033 19.6 0.1 4.3 3 1 2 5 5 5 2 FAD binding domain GIDA PF01134.17 AJZ75488.1 - 9.1e-08 31.3 0.4 0.016 14.0 0.0 4.0 4 0 0 4 4 4 2 Glucose inhibited division protein A DAO PF01266.19 AJZ75488.1 - 2.4e-07 29.9 0.4 0.0014 17.6 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 AJZ75488.1 - 9.4e-06 24.3 0.6 0.02 13.3 0.0 3.4 3 1 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.1 AJZ75488.1 - 1.4e-05 24.2 0.0 0.0018 17.2 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 AJZ75488.1 - 1.6e-05 24.1 0.0 0.0041 16.2 0.0 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_7 PF13241.1 AJZ75488.1 - 0.00016 21.8 0.1 0.0025 18.0 0.1 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 AJZ75488.1 - 0.0011 18.7 1.6 0.44 10.2 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 AJZ75488.1 - 0.0014 17.6 0.2 2.5 6.9 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_3 PF01494.14 AJZ75488.1 - 0.0042 16.1 0.7 0.25 10.3 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 AJZ75488.1 - 0.019 14.9 0.2 0.093 12.7 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 AJZ75488.1 - 0.019 13.5 0.3 0.68 8.4 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.2 AJZ75488.1 - 0.13 11.3 0.9 0.17 10.9 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Response_reg PF00072.19 AJZ75489.1 - 1.2e-14 54.2 0.1 1.7e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain PALP PF00291.20 AJZ75490.1 - 2.3e-56 191.3 0.0 2.8e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TusA PF01206.12 AJZ75491.1 - 1.4e-24 85.4 0.0 1.5e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.4 AJZ75491.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) IQ PF00612.22 AJZ75492.1 - 0.022 14.3 0.1 0.043 13.4 0.1 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF1454 PF07305.7 AJZ75492.1 - 0.092 11.8 0.1 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) Ribosomal_S11 PF00411.14 AJZ75492.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S11 F420_ligase PF01996.11 AJZ75493.1 - 1e-61 207.9 0.1 1.1e-61 207.7 0.1 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase HAD PF12710.2 AJZ75494.1 - 7.4e-07 29.5 0.3 9.1e-07 29.2 0.2 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AJZ75494.1 - 9.9e-06 26.1 0.1 2.3e-05 24.9 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AJZ75494.1 - 0.00012 21.7 0.2 0.0022 17.6 0.2 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AJZ75494.1 - 0.00015 22.0 0.0 0.00042 20.5 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase ProRS-C_1 PF09180.6 AJZ75495.1 - 7.6e-20 70.6 2.8 9.2e-20 70.3 0.8 2.0 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 AJZ75495.1 - 1.2e-18 67.3 0.0 2.5e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AJZ75495.1 - 1.3e-16 60.3 0.2 2.8e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain DUF1351 PF07083.6 AJZ75495.1 - 0.011 15.3 1.8 0.011 15.3 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) ABC_tran PF00005.22 AJZ75496.1 - 9.7e-32 110.1 0.1 1.4e-31 109.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJZ75496.1 - 2.4e-07 31.0 2.6 6.7e-06 26.2 1.8 2.1 1 1 0 1 1 1 1 AAA domain oligo_HPY PF08352.7 AJZ75496.1 - 1.8e-06 28.1 0.1 4.2e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.1 AJZ75496.1 - 0.00017 21.7 0.5 0.0023 18.0 0.3 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 AJZ75496.1 - 0.00042 19.6 0.1 0.00066 18.9 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AJZ75496.1 - 0.00043 20.3 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 AJZ75496.1 - 0.00048 19.6 0.1 0.00097 18.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 AJZ75496.1 - 0.0006 18.7 0.1 0.0012 17.8 0.1 1.4 1 1 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 AJZ75496.1 - 0.0027 16.8 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 AJZ75496.1 - 0.003 18.3 0.1 0.0057 17.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AJZ75496.1 - 0.0031 17.8 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AJZ75496.1 - 0.0038 17.4 0.5 0.038 14.2 0.3 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 AJZ75496.1 - 0.013 14.5 0.1 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 AJZ75496.1 - 0.016 14.5 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 AJZ75496.1 - 0.02 14.3 0.1 0.043 13.2 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_15 PF13175.1 AJZ75496.1 - 0.022 13.8 4.2 0.21 10.5 0.4 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 AJZ75496.1 - 0.023 14.1 0.6 0.22 10.9 0.2 2.3 1 1 1 2 2 2 0 AAA-like domain Myosin_head PF00063.16 AJZ75496.1 - 0.03 12.3 0.1 0.044 11.8 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) AAA_13 PF13166.1 AJZ75496.1 - 0.052 12.0 0.0 0.62 8.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 AJZ75496.1 - 0.055 12.9 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 AJZ75496.1 - 0.056 12.2 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.15 AJZ75496.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Mg_chelatase PF01078.16 AJZ75496.1 - 0.072 12.2 0.0 0.16 11.0 0.0 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AJZ75496.1 - 0.085 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 AJZ75496.1 - 0.086 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 AJZ75496.1 - 0.089 12.9 0.5 1 9.5 0.2 2.6 2 1 1 3 3 3 0 RNA helicase KaiC PF06745.8 AJZ75496.1 - 0.094 11.8 0.8 0.13 11.3 0.2 1.6 2 1 0 2 2 1 0 KaiC Sigma54_activ_2 PF14532.1 AJZ75496.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DEAD PF00270.24 AJZ75496.1 - 0.13 11.7 0.1 0.28 10.6 0.1 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase NACHT PF05729.7 AJZ75496.1 - 0.13 11.8 0.1 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain zf-Di19 PF05605.7 AJZ75497.1 - 0.0096 16.0 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding FAM72 PF14976.1 AJZ75497.1 - 0.039 13.7 0.1 0.063 13.1 0.0 1.4 1 1 0 1 1 1 0 FAM72 protein DUF3133 PF11331.3 AJZ75497.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) PAC2 PF09754.4 AJZ75498.1 - 5e-19 69.0 0.0 6e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 PAC2 family LysE PF01810.13 AJZ75499.1 - 1.2e-26 93.1 16.9 1.7e-26 92.6 11.7 1.1 1 0 0 1 1 1 1 LysE type translocator DDE_Tnp_1_7 PF13843.1 AJZ75500.1 - 0.0076 15.3 0.0 0.008 15.2 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DUF1871 PF08958.5 AJZ75500.1 - 0.065 13.3 0.3 0.094 12.7 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1871) IMS PF00817.15 AJZ75501.1 - 1.1e-39 135.5 0.1 2.6e-39 134.4 0.0 1.6 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 AJZ75501.1 - 4.9e-17 62.0 1.3 1.4e-16 60.6 0.3 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 AJZ75501.1 - 2.7e-08 33.3 0.0 6.6e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.1 AJZ75501.1 - 0.001 19.1 0.0 0.0038 17.3 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 AJZ75501.1 - 0.0011 18.5 0.0 0.0036 16.8 0.0 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.3 AJZ75501.1 - 0.12 12.3 0.1 1.8 8.5 0.0 2.4 1 1 0 2 2 2 0 Pathogenicity locus Exosortase_EpsH PF09721.5 AJZ75502.1 - 8.4e-07 28.4 16.5 8.4e-07 28.4 11.5 2.0 1 1 1 2 2 2 1 Transmembrane exosortase (Exosortase_EpsH) DUF998 PF06197.8 AJZ75502.1 - 0.0025 17.1 2.6 0.0025 17.1 1.8 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF998) Seryl_tRNA_N PF02403.17 AJZ75503.1 - 3.3 7.7 6.7 11 6.0 0.1 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tubulin PF00091.20 AJZ75504.1 - 5.7e-15 55.7 0.0 1.3e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF650 PF04894.7 AJZ75505.1 - 1.7e-84 283.5 0.0 2.5e-84 283.0 0.0 1.1 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF650) DUF651 PF04895.7 AJZ75505.1 - 1.1e-37 128.0 0.0 1.8e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF651) NfeD PF01957.13 AJZ75507.1 - 1.3 9.1 5.3 1.1 9.3 2.4 1.9 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding zf-C2H2 PF00096.21 AJZ75509.1 - 0.0007 19.7 1.4 0.0013 18.9 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 AJZ75509.1 - 0.00093 19.2 1.2 0.0028 17.7 0.8 1.8 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 AJZ75509.1 - 0.0068 16.6 0.8 0.013 15.7 0.5 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger BAR PF03114.13 AJZ75509.1 - 0.054 12.9 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 BAR domain zf-Mss51 PF13824.1 AJZ75509.1 - 0.056 13.3 1.1 0.093 12.6 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 FAT PF02259.18 AJZ75509.1 - 0.078 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 FAT domain OrfB_Zn_ribbon PF07282.6 AJZ75509.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1690 PF07956.6 AJZ75510.1 - 0.0014 18.5 2.6 0.0027 17.6 1.8 1.6 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) APG17 PF04108.7 AJZ75510.1 - 0.0062 15.3 3.9 0.0075 15.1 1.9 1.5 1 1 0 1 1 1 1 Autophagy protein Apg17 DUF4404 PF14357.1 AJZ75510.1 - 0.024 15.0 0.3 0.053 13.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF1342 PF07072.6 AJZ75510.1 - 0.1 12.2 2.2 0.13 11.9 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) RFC1 PF08519.7 AJZ75510.1 - 0.44 10.2 5.4 3.3 7.4 3.7 2.3 1 1 0 1 1 1 0 Replication factor RFC1 C terminal domain Leuk-A4-hydro_C PF09127.6 AJZ75510.1 - 0.67 9.5 4.5 0.43 10.1 0.7 2.2 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal ABC2_membrane_3 PF12698.2 AJZ75510.1 - 0.77 8.7 7.7 1.1 8.2 5.4 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein SURF1 PF02104.10 AJZ75511.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 1 0 1 1 1 0 SURF1 family TRAP_alpha PF03896.11 AJZ75511.1 - 0.17 10.8 14.8 0.013 14.4 2.8 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit FYDLN_acid PF09538.5 AJZ75511.1 - 5.1 7.7 10.6 11 6.6 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) NAD_binding_2 PF03446.10 AJZ75512.1 - 1.4e-42 145.2 0.3 2.4e-42 144.5 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 AJZ75512.1 - 1.6e-22 79.8 0.2 2.3e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 AJZ75512.1 - 1.8e-08 34.6 0.2 6.1e-08 32.9 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 AJZ75512.1 - 1.1e-06 27.9 0.0 2.7e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 AJZ75512.1 - 1.2e-05 24.8 0.1 2e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 AJZ75512.1 - 0.0036 17.3 0.1 0.0056 16.7 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 AJZ75512.1 - 0.0054 16.1 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.7 AJZ75512.1 - 0.006 15.9 0.1 0.021 14.1 0.1 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 AJZ75512.1 - 0.01 15.5 0.1 0.026 14.1 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 AJZ75512.1 - 0.014 14.6 0.1 0.029 13.6 0.1 1.5 2 0 0 2 2 2 0 NmrA-like family Rossmann-like PF10727.4 AJZ75512.1 - 0.029 14.0 0.0 0.17 11.5 0.1 2.0 1 1 1 2 2 2 0 Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 AJZ75512.1 - 0.069 12.8 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3797 PF12677.2 AJZ75513.1 - 0.0049 16.4 0.5 0.0074 15.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3797) zf-C2H2_3 PF13878.1 AJZ75513.1 - 0.53 9.9 2.3 2.1 7.9 1.6 2.0 1 1 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO TPR_11 PF13414.1 AJZ75514.1 - 7.2e-24 83.2 2.0 4.8e-09 35.7 0.1 2.9 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 AJZ75514.1 - 1e-19 69.2 0.3 5.8e-07 28.8 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 AJZ75514.1 - 1.5e-13 49.4 0.0 0.0013 18.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ75514.1 - 1e-12 47.7 0.1 3.6e-07 30.0 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AJZ75514.1 - 1.3e-11 44.8 0.0 0.00076 20.0 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ75514.1 - 2.6e-10 39.3 0.4 0.014 15.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 AJZ75514.1 - 9e-09 35.3 0.4 0.003 17.6 0.0 2.5 1 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 AJZ75514.1 - 7.1e-08 31.6 0.1 2.4 8.1 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJZ75514.1 - 7.7e-08 32.0 0.0 0.045 13.6 0.0 3.4 3 1 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 AJZ75514.1 - 2e-07 31.0 0.0 0.84 10.4 0.0 4.0 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ75514.1 - 8.3e-07 29.2 0.2 0.0071 16.6 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 AJZ75514.1 - 1.1e-06 28.3 0.1 0.096 12.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 AJZ75514.1 - 2.7e-06 27.4 0.0 1.4 9.5 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 AJZ75514.1 - 6.6e-06 25.8 0.0 0.035 13.9 0.0 2.9 2 1 1 3 3 3 3 Tetratricopeptide repeat MIT PF04212.13 AJZ75514.1 - 0.00047 19.9 0.3 39 4.2 0.0 4.6 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 AJZ75514.1 - 0.0042 16.9 0.2 0.69 9.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 AJZ75514.1 - 0.0043 16.8 2.6 1.2 9.0 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.3 AJZ75514.1 - 0.047 12.4 0.1 0.61 8.7 0.0 1.9 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 AJZ75514.1 - 0.09 11.8 0.3 1.5 7.8 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF627 PF04781.7 AJZ75514.1 - 0.12 11.9 0.1 14 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF627) DUF1258 PF06869.7 AJZ75515.1 - 0.045 12.8 0.9 0.049 12.7 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Cas_CXXC_CXXC PF09706.5 AJZ75515.1 - 0.17 12.0 0.3 0.17 12.0 0.2 2.5 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) DUF1272 PF06906.6 AJZ75515.1 - 0.2 11.5 8.7 0.32 10.8 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.2 AJZ75515.1 - 0.27 11.0 12.4 6.6 6.6 8.6 2.1 1 1 0 1 1 1 0 Double zinc ribbon SBP_bac_5 PF00496.17 AJZ75516.1 - 6.4e-24 84.4 10.7 6.6e-19 67.9 0.0 4.0 2 2 1 3 3 3 3 Bacterial extracellular solute-binding proteins, family 5 Middle Mrr_cat PF04471.7 AJZ75517.1 - 0.00017 21.3 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Hjc PF01870.13 AJZ75517.1 - 0.0053 16.3 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) NERD PF08378.6 AJZ75517.1 - 0.015 15.5 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Nuclease-related domain DUF2070 PF09843.4 AJZ75518.1 - 7.6e-42 142.7 0.0 1.1e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) DUF2306 PF10067.4 AJZ75518.1 - 0.22 11.6 2.7 0.37 10.9 1.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2306) IncA PF04156.9 AJZ75519.1 - 0.0013 18.3 0.1 0.0018 17.9 0.1 1.2 1 0 0 1 1 1 1 IncA protein Nucleoporin_C PF03177.9 AJZ75519.1 - 0.027 13.0 2.2 0.031 12.7 1.5 1.0 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal DUF948 PF06103.6 AJZ75519.1 - 0.036 13.9 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 AJZ75519.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Auto_anti-p27 PF06677.7 AJZ75520.1 - 1.3e-11 44.0 2.1 1.9e-11 43.5 1.5 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TIP120 PF08623.5 AJZ75520.1 - 0.0016 18.0 0.8 0.002 17.7 0.6 1.2 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) DUF4391 PF14335.1 AJZ75520.1 - 0.0091 15.4 0.6 0.0096 15.3 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) TF_Zn_Ribbon PF08271.7 AJZ75520.1 - 0.024 13.9 1.2 0.037 13.3 0.9 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Matrilin_ccoil PF10393.4 AJZ75520.1 - 0.04 13.2 1.0 0.062 12.6 0.4 1.6 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1178 PF06676.6 AJZ75520.1 - 0.046 13.9 0.3 0.051 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) DUF2031 PF09592.5 AJZ75520.1 - 0.068 12.3 2.1 0.1 11.7 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) COG2 PF06148.6 AJZ75520.1 - 0.081 12.7 0.9 0.1 12.4 0.7 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-C4pol PF14260.1 AJZ75520.1 - 0.093 12.7 1.6 0.39 10.7 1.1 2.0 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta NPV_P10 PF05531.7 AJZ75520.1 - 0.16 12.2 4.2 0.34 11.1 2.9 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Lar_restr_allev PF14354.1 AJZ75520.1 - 0.19 12.0 1.4 1.3 9.3 1.0 2.1 1 1 0 1 1 1 0 Restriction alleviation protein Lar Prim_Zn_Ribbon PF08273.7 AJZ75520.1 - 0.27 11.3 3.1 0.65 10.1 2.2 1.6 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase DUF948 PF06103.6 AJZ75520.1 - 0.36 10.7 2.9 0.3 10.9 1.2 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SUI1 PF01253.17 AJZ75521.1 - 4.6e-20 71.2 0.2 5.5e-20 70.9 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Abi PF02517.11 AJZ75522.1 - 5.9e-10 39.1 20.8 8.4e-10 38.6 12.5 2.6 2 1 0 2 2 2 1 CAAX protease self-immunity DUF3098 PF11297.3 AJZ75522.1 - 0.0091 15.6 0.7 0.0091 15.6 0.5 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF3098) Pox_I5 PF04713.7 AJZ75522.1 - 0.034 13.8 1.2 0.034 13.8 0.8 2.5 2 0 0 2 2 2 0 Poxvirus protein I5 Rifin_STEVOR PF02009.11 AJZ75522.1 - 0.8 9.2 2.1 1.8 8.1 0.5 1.9 2 0 0 2 2 2 0 Rifin/stevor family DUF443 PF04276.7 AJZ75522.1 - 5.1 6.4 14.0 0.17 11.3 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF443) UPF0052 PF01933.13 AJZ75523.1 - 7.1e-46 156.8 0.0 9.3e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 CofC PF01983.11 AJZ75524.1 - 3.2e-26 91.6 0.8 3.7e-26 91.4 0.6 1.0 1 0 0 1 1 1 1 Guanylyl transferase CofC like NTP_transf_3 PF12804.2 AJZ75524.1 - 1.2e-07 31.9 0.0 1.5e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 AJZ75524.1 - 6.4e-05 22.3 0.2 9.9e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase CTP_transf_3 PF02348.14 AJZ75524.1 - 0.0059 16.2 0.1 0.0075 15.9 0.1 1.2 1 0 0 1 1 1 1 Cytidylyltransferase ADH_zinc_N PF00107.21 AJZ75524.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase A2M_N PF01835.14 AJZ75525.1 - 1e-33 115.5 11.4 7.8e-06 26.0 0.0 9.4 8 1 0 8 8 8 6 MG2 domain LTD PF00932.14 AJZ75525.1 - 3.8e-11 43.0 1.2 2.2e-10 40.5 0.8 2.4 1 0 0 1 1 1 1 Lamin Tail Domain Arrestin_C PF02752.17 AJZ75525.1 - 2.1e-05 24.6 5.4 1.7 8.7 0.1 6.0 6 1 0 6 6 6 2 Arrestin (or S-antigen), C-terminal domain Peptidase_M24 PF00557.19 AJZ75526.1 - 1.2e-34 119.6 0.0 1.5e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 XendoU PF09412.5 AJZ75526.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Endoribonuclease XendoU DnaJ_CXXCXGXG PF00684.14 AJZ75527.1 - 0.013 15.5 4.8 0.018 15.0 3.3 1.3 1 0 0 1 1 1 0 DnaJ central domain COMP PF11598.3 AJZ75527.1 - 0.23 11.5 0.5 0.23 11.5 0.4 1.8 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein zf-TFIIB PF13453.1 AJZ75527.1 - 0.89 8.8 4.5 2.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn-ribbon_8 PF09723.5 AJZ75527.1 - 1.2 9.1 7.6 1.2 9.1 0.5 2.0 1 1 1 2 2 2 0 Zinc ribbon domain DUF1512 PF07431.7 AJZ75528.1 - 2e-103 345.8 3.4 2.3e-103 345.6 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1512) tRNA_lig_CPD PF08302.6 AJZ75528.1 - 0.03 13.5 0.3 0.05 12.8 0.2 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain DUF948 PF06103.6 AJZ75528.1 - 0.041 13.7 0.9 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PRANC PF09372.5 AJZ75528.1 - 0.063 13.2 4.2 2 8.4 0.4 2.7 2 0 0 2 2 2 0 PRANC domain TBP PF00352.16 AJZ75529.1 - 1e-61 204.2 0.0 6.3e-31 105.5 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AJZ75529.1 - 1.9e-06 27.8 0.0 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) B3_4 PF03483.12 AJZ75529.1 - 0.075 12.4 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 B3/4 domain tRNA_bind PF01588.15 AJZ75530.1 - 1.2e-19 69.9 0.0 1.4e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Putative tRNA binding domain Polyketide_cyc2 PF10604.4 AJZ75532.1 - 1.5e-15 57.5 0.0 1.7e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AJZ75532.1 - 2.1e-09 37.4 0.0 3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 AJZ75532.1 - 3.2e-05 24.0 0.1 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein COXG PF06240.8 AJZ75532.1 - 0.064 12.9 0.6 0.3 10.7 0.4 1.8 1 1 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) Glycos_transf_2 PF00535.21 AJZ75533.1 - 1.1e-26 93.4 0.0 1.7e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AJZ75533.1 - 1.3e-19 70.9 0.0 1.8e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AJZ75533.1 - 2.9e-09 36.4 0.0 5.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 AJZ75533.1 - 0.00029 20.0 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 AJZ75533.1 - 0.00031 21.0 0.0 0.00068 19.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Trypsin_2 PF13365.1 AJZ75534.1 - 5.4e-23 81.2 0.1 1.1e-22 80.2 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 AJZ75534.1 - 1.1e-14 54.5 0.3 1.1e-13 51.3 0.0 2.4 2 1 0 2 2 2 1 Trypsin PDZ_2 PF13180.1 AJZ75534.1 - 2.6e-10 40.0 1.2 2.6e-10 40.0 0.9 2.8 3 1 0 3 3 3 1 PDZ domain Peptidase_S29 PF02907.10 AJZ75534.1 - 0.0014 18.2 0.0 0.0034 16.8 0.0 1.7 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.4 AJZ75534.1 - 0.0029 16.1 0.1 0.016 13.6 0.1 1.8 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S7 PF00949.16 AJZ75534.1 - 0.087 12.2 0.1 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease PDZ PF00595.19 AJZ75534.1 - 0.99 9.6 5.5 3 8.0 0.0 3.7 4 1 1 5 5 5 0 PDZ domain (Also known as DHR or GLGF) Radical_SAM PF04055.16 AJZ75535.1 - 5.3e-08 33.2 0.0 7.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily BATS PF06968.8 AJZ75535.1 - 0.023 14.5 0.1 0.056 13.2 0.1 1.6 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain SpoU_sub_bind PF08032.7 AJZ75535.1 - 0.11 12.6 0.1 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding PSD1 PF07587.6 AJZ75535.1 - 0.13 11.6 0.1 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) PmbA_TldD PF01523.11 AJZ75536.1 - 6.2e-44 150.4 0.1 7.4e-44 150.1 0.1 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase DUF3658 PF12395.3 AJZ75536.1 - 0.044 13.3 0.1 0.089 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function HTH_45 PF14947.1 AJZ75537.1 - 0.091 12.5 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix PAC2 PF09754.4 AJZ75538.1 - 4.1e-38 131.4 0.0 4.9e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 PAC2 family DUF3410 PF11890.3 AJZ75538.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) Atg8 PF02991.11 AJZ75538.1 - 0.046 13.6 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Autophagy protein Atg8 ubiquitin like AIRS_C PF02769.17 AJZ75539.1 - 5.6e-22 78.3 0.0 8.9e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 AJZ75539.1 - 3.6e-17 62.3 1.5 1e-16 60.9 1.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Na_H_Exchanger PF00999.16 AJZ75540.1 - 5.3e-66 222.7 55.3 6.9e-66 222.3 38.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PspB PF06667.7 AJZ75540.1 - 0.062 13.2 0.4 0.47 10.4 0.1 2.5 2 0 0 2 2 2 0 Phage shock protein B DUF2175 PF09943.4 AJZ75541.1 - 7.4e-05 22.7 1.4 7.4e-05 22.7 1.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) LIM PF00412.17 AJZ75541.1 - 0.00068 19.6 0.3 0.0012 18.8 0.2 1.4 1 0 0 1 1 1 1 LIM domain RNase_H2-Ydr279 PF09468.5 AJZ75541.1 - 0.055 12.6 12.8 0.06 12.5 8.9 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 AJZ75541.1 - 0.53 10.1 9.7 0.54 10.1 6.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SART-1 PF03343.8 AJZ75541.1 - 0.64 8.2 19.9 1.1 7.5 13.8 1.3 1 1 0 1 1 1 0 SART-1 family CENP-H PF05837.7 AJZ75541.1 - 8.3 6.6 10.3 10 6.3 7.1 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Radical_SAM PF04055.16 AJZ75542.1 - 1.4e-20 74.1 0.1 6.1e-20 72.0 0.0 2.1 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 AJZ75542.1 - 1.5e-05 24.9 0.2 7e-05 22.7 0.1 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AJZ75542.1 - 0.12 12.5 0.0 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain tRNA-synt_1f PF01921.13 AJZ75543.1 - 9.3e-109 363.3 0.0 1.2e-108 362.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (K) P2 PF07194.6 AJZ75543.1 - 0.015 15.1 0.7 1.2 9.0 0.4 3.1 2 1 0 2 2 2 0 P2 response regulator binding domain tRNA-synt_1g PF09334.6 AJZ75543.1 - 0.028 13.1 0.5 0.076 11.6 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (M) CLASP_N PF12348.3 AJZ75543.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 CLASP N terminal VPEP PF07589.6 AJZ75544.1 - 0.0033 17.2 1.7 0.05 13.4 0.1 2.2 2 0 0 2 2 2 1 PEP-CTERM motif Polysacc_synt_3 PF13440.1 AJZ75544.1 - 0.0055 16.2 0.2 0.0058 16.1 0.2 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF3953 PF13129.1 AJZ75544.1 - 0.012 15.1 0.1 0.012 15.1 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3953) DUF4131 PF13567.1 AJZ75544.1 - 0.014 14.7 0.2 0.015 14.6 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Peptidase_A8 PF01252.13 AJZ75544.1 - 0.031 13.8 0.2 0.032 13.8 0.1 1.0 1 0 0 1 1 1 0 Signal peptidase (SPase) II DUF1129 PF06570.6 AJZ75544.1 - 0.12 11.6 0.2 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF872 PF05915.7 AJZ75544.1 - 0.27 11.1 2.3 0.69 9.7 1.6 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) SdpI PF13630.1 AJZ75544.1 - 2.9 7.6 7.6 6 6.6 5.2 1.5 1 1 0 1 1 1 0 SdpI/YhfL protein family WEMBL PF05701.6 AJZ75545.1 - 8.4e-09 34.4 56.1 4.7e-06 25.3 13.0 3.6 1 1 2 3 3 3 3 Weak chloroplast movement under blue light DUF3584 PF12128.3 AJZ75545.1 - 0.016 12.5 46.9 0.094 10.0 12.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF869 PF05911.6 AJZ75545.1 - 0.074 11.2 49.0 0.099 10.8 33.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Fez1 PF06818.10 AJZ75545.1 - 0.095 12.7 39.2 0.42 10.6 12.0 3.0 1 1 2 3 3 3 0 Fez1 TPR_MLP1_2 PF07926.7 AJZ75545.1 - 0.33 10.7 55.3 0.04 13.6 16.3 3.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.8 AJZ75545.1 - 0.37 10.3 42.1 0.035 13.6 9.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) LPP PF04728.8 AJZ75545.1 - 0.46 10.3 3.9 1.2 8.9 0.1 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper IncA PF04156.9 AJZ75545.1 - 0.72 9.4 50.5 0.15 11.6 15.2 2.9 1 1 1 2 2 2 0 IncA protein APG6 PF04111.7 AJZ75545.1 - 1.2 8.1 46.3 0.075 12.0 13.4 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 ERM PF00769.14 AJZ75545.1 - 1.3 8.4 55.5 1.8 8.0 17.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Filament PF00038.16 AJZ75545.1 - 1.4 8.2 47.9 1.1 8.6 8.3 2.4 1 1 1 2 2 2 0 Intermediate filament protein LURAP PF14854.1 AJZ75545.1 - 2.4 7.8 8.4 2.9 7.6 1.3 3.0 2 1 0 2 2 2 0 Leucine rich adaptor protein zf-AN1 PF01428.11 AJZ75546.1 - 2.5e-07 30.4 5.2 2.5e-07 30.4 3.6 2.2 3 0 0 3 3 3 1 AN1-like Zinc finger SHOCT PF09851.4 AJZ75546.1 - 0.0001 21.6 0.6 0.00017 20.9 0.4 1.4 1 0 0 1 1 1 1 Short C-terminal domain DNA_RNApol_7kD PF03604.8 AJZ75546.1 - 0.033 13.6 1.2 4.3 6.8 0.1 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-ZPR1 PF03367.8 AJZ75546.1 - 0.26 10.4 1.5 10 5.2 0.4 2.2 2 0 0 2 2 2 0 ZPR1 zinc-finger domain zf-C2H2_4 PF13894.1 AJZ75546.1 - 2.5 8.6 6.1 57 4.3 0.0 2.8 2 2 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AJZ75546.1 - 6.5 7.2 7.5 16 6.0 0.0 3.2 4 0 0 4 4 4 0 Zinc-finger double domain DM13 PF10517.4 AJZ75547.1 - 3.2e-28 98.2 0.0 4.4e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Electron transfer DM13 DM13 PF10517.4 AJZ75548.1 - 1.9e-09 37.8 0.1 3.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Electron transfer DM13 DUF2407_C PF13373.1 AJZ75549.1 - 1.2 9.0 8.5 4 7.3 0.1 2.8 3 0 0 3 3 3 0 DUF2407 C-terminal domain Tim17 PF02466.14 AJZ75550.1 - 0.0053 16.7 3.7 2.6 8.1 3.4 3.0 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF3816 PF12822.2 AJZ75550.1 - 0.085 12.7 16.6 0.38 10.6 11.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF2407_C PF13373.1 AJZ75550.1 - 0.9 9.4 2.7 3 7.7 0.0 2.5 2 1 0 2 2 2 0 DUF2407 C-terminal domain VirB3 PF05101.8 AJZ75550.1 - 2.4 8.2 6.7 23 5.0 0.0 3.1 2 1 1 3 3 3 0 Type IV secretory pathway, VirB3-like protein DnaJ PF00226.26 AJZ75551.1 - 7.5e-11 41.6 0.1 1.6e-10 40.5 0.1 1.7 1 1 0 1 1 1 1 DnaJ domain Toxin_R_bind_N PF07953.7 AJZ75551.1 - 0.053 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding Radical_SAM PF04055.16 AJZ75552.1 - 1.8e-12 47.7 0.2 3.3e-12 46.9 0.1 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 AJZ75552.1 - 2.3e-08 34.0 0.2 6.6e-08 32.6 0.1 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AJZ75552.1 - 8.2e-08 32.4 0.4 1.8e-07 31.3 0.3 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain SSURE PF11966.3 AJZ75552.1 - 0.026 14.0 0.4 0.24 11.0 0.3 2.2 1 1 0 1 1 1 0 Fibronectin-binding repeat TRAM PF01938.15 AJZ75553.1 - 2.3e-15 56.0 0.9 2.8e-15 55.8 0.6 1.1 1 0 0 1 1 1 1 TRAM domain Alpha_kinase PF02816.13 AJZ75554.1 - 0.019 14.6 0.2 0.022 14.3 0.1 1.0 1 0 0 1 1 1 0 Alpha-kinase family KAP_NTPase PF07693.9 AJZ75555.1 - 1.7e-38 132.4 7.3 3.1e-38 131.5 5.1 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.1 AJZ75555.1 - 1e-06 28.8 0.0 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 AJZ75555.1 - 4.9e-06 26.3 0.0 0.002 17.8 0.0 3.6 2 1 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 AJZ75555.1 - 1.1e-05 24.4 0.9 4.6e-05 22.4 0.6 2.1 1 1 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 AJZ75555.1 - 2.8e-05 23.9 9.2 3.8e-05 23.4 3.7 2.7 1 1 1 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 AJZ75555.1 - 3.6e-05 23.9 1.1 0.0014 18.7 0.2 3.0 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 AJZ75555.1 - 5.1e-05 23.4 2.4 0.004 17.3 0.8 3.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AJZ75555.1 - 0.0045 16.8 11.6 0.043 13.7 0.0 3.7 3 1 0 4 4 4 2 AAA domain EIF_2_alpha PF07541.7 AJZ75555.1 - 0.0052 16.4 1.0 0.025 14.3 0.7 2.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit AAA_25 PF13481.1 AJZ75555.1 - 0.0058 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AJZ75555.1 - 0.0064 17.3 1.8 0.068 13.9 0.1 3.3 2 2 1 3 3 2 1 AAA domain RNA_helicase PF00910.17 AJZ75555.1 - 0.0084 16.2 0.2 0.16 12.1 0.0 3.0 2 1 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 AJZ75555.1 - 0.011 16.0 0.2 0.03 14.6 0.1 1.8 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 AJZ75555.1 - 0.021 14.2 0.2 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 AJZ75555.1 - 0.021 15.1 7.6 0.025 14.8 0.9 3.4 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 AJZ75555.1 - 0.06 12.9 0.4 0.13 11.8 0.3 1.7 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 AJZ75555.1 - 0.083 12.5 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 AJZ75555.1 - 0.1 12.3 0.0 9.8 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.7 AJZ75555.1 - 0.17 11.0 4.9 0.13 11.3 1.4 2.4 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Bac_DnaA PF00308.13 AJZ75555.1 - 0.22 11.1 5.8 0.39 10.3 0.0 3.5 3 1 1 4 4 4 0 Bacterial dnaA protein AAA_30 PF13604.1 AJZ75555.1 - 0.25 10.9 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MIP PF00230.15 AJZ75556.1 - 1.1e-53 182.0 19.4 1.5e-53 181.6 13.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein Ldr_toxin PF13940.1 AJZ75556.1 - 0.053 13.3 0.9 0.16 11.7 0.6 1.9 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system AhpC-TSA PF00578.16 AJZ75557.1 - 1e-42 144.6 0.3 1.2e-42 144.5 0.2 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AJZ75557.1 - 1.9e-27 95.6 0.1 2.1e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 AJZ75557.1 - 1e-06 28.6 0.1 2.1e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.7 AJZ75557.1 - 2.2e-06 27.2 0.0 2.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) SCO1-SenC PF02630.9 AJZ75557.1 - 6.4e-06 25.9 1.2 1e-05 25.2 0.8 1.3 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 AJZ75557.1 - 0.00071 19.6 0.1 0.001 19.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like GSHPx PF00255.14 AJZ75557.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase M PF02370.11 AJZ75558.1 - 0.032 14.5 4.4 0.076 13.3 3.0 1.6 1 0 0 1 1 1 0 M protein repeat PAT1 PF09770.4 AJZ75558.1 - 0.061 11.5 14.4 0.074 11.2 10.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Osmo_CC PF08946.5 AJZ75558.1 - 0.26 11.3 1.4 0.51 10.4 1.0 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil UbiD PF01977.11 AJZ75560.1 - 3.7e-154 513.0 0.1 4.3e-154 512.8 0.1 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Radical_SAM PF04055.16 AJZ75561.1 - 2.7e-15 56.9 0.0 3.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily TrmB PF01978.14 AJZ75561.1 - 0.15 11.8 0.1 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DeoC PF01791.4 AJZ75562.1 - 5.4e-46 156.7 0.0 6.4e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase YjeF_N PF03853.10 AJZ75562.1 - 0.0027 17.3 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus PEP_mutase PF13714.1 AJZ75562.1 - 0.096 11.8 0.1 0.35 10.0 0.0 1.9 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase DHQS PF01959.11 AJZ75563.1 - 3.6e-113 377.8 0.4 4.3e-113 377.6 0.3 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase (EC 4.6.1.3) CppA_N PF14506.1 AJZ75563.1 - 0.049 13.3 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 CppA N-terminal DHquinase_I PF01487.10 AJZ75564.1 - 6.8e-53 179.6 0.0 7.6e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Type I 3-dehydroquinase SEFIR PF08357.6 AJZ75564.1 - 0.054 13.5 0.1 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 SEFIR domain Shikimate_dh_N PF08501.6 AJZ75565.1 - 5e-30 103.4 0.0 9.7e-30 102.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 AJZ75565.1 - 5.8e-14 52.3 0.2 9.5e-14 51.6 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 AJZ75565.1 - 0.00081 18.4 0.1 0.0011 18.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 AJZ75565.1 - 0.013 15.9 0.1 0.022 15.1 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GARS_N PF02844.10 AJZ75565.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain NAD_binding_7 PF13241.1 AJZ75565.1 - 0.084 13.1 0.1 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.20 AJZ75565.1 - 0.09 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase GHMP_kinases_N PF00288.21 AJZ75566.1 - 3.2e-10 39.9 1.0 7.6e-10 38.7 0.7 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AJZ75566.1 - 1.5e-05 25.0 0.1 8.3e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal EPSP_synthase PF00275.15 AJZ75567.1 - 2.5e-104 349.0 0.1 3e-104 348.7 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Chorismate_synt PF01264.16 AJZ75568.1 - 1.6e-139 464.2 0.2 1.8e-139 464.0 0.2 1.0 1 0 0 1 1 1 1 Chorismate synthase PDH PF02153.12 AJZ75569.1 - 4.8e-24 84.6 0.2 6.2e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 AJZ75569.1 - 3.4e-06 27.0 0.0 9.7e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 AJZ75569.1 - 1.2e-05 24.5 0.0 2.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AJZ75569.1 - 4.7e-05 23.7 0.4 0.00032 21.0 0.0 2.5 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Phage-tail_1 PF09097.5 AJZ75569.1 - 0.0052 16.3 0.3 0.0098 15.4 0.2 1.4 1 0 0 1 1 1 1 Baseplate structural protein, domain 1 3HCDH_N PF02737.13 AJZ75569.1 - 0.023 14.3 0.0 0.063 12.9 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 AJZ75569.1 - 0.03 14.0 0.9 0.74 9.5 0.0 2.8 2 1 1 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CoA_binding_2 PF13380.1 AJZ75569.1 - 0.076 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain NAD_binding_10 PF13460.1 AJZ75569.1 - 0.088 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding NUDIX PF00293.23 AJZ75570.1 - 2.3e-09 36.9 0.0 2.7e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 AJZ75570.1 - 0.00073 18.9 0.1 0.0015 17.9 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain ThiC PF01964.13 AJZ75571.1 - 3.9e-177 588.9 0.6 4.5e-177 588.7 0.4 1.0 1 0 0 1 1 1 1 ThiC family Plectin PF00681.15 AJZ75571.1 - 0.041 13.4 0.0 54 3.4 0.0 4.0 4 0 0 4 4 4 0 Plectin repeat Phos_pyr_kin PF08543.7 AJZ75572.1 - 8.6e-68 228.1 2.0 8.6e-68 228.1 1.4 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Aldolase_2 PF10120.4 AJZ75572.1 - 6e-57 191.7 0.0 1.1e-56 190.8 0.0 1.5 1 0 0 1 1 1 1 Putative aldolase PfkB PF00294.19 AJZ75572.1 - 2.3e-09 36.8 0.1 3.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 AJZ75572.1 - 5.4e-08 32.4 0.6 9.4e-08 31.6 0.4 1.4 1 1 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 AJZ75572.1 - 3.1e-05 23.2 0.1 7e-05 22.1 0.1 1.5 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family eRF1_2 PF03464.10 AJZ75572.1 - 0.024 14.9 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 eRF1 domain 2 NTP_transferase PF00483.18 AJZ75573.1 - 1.5e-35 122.6 0.0 1.7e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AJZ75573.1 - 2.1e-11 44.1 0.0 2.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 AJZ75573.1 - 0.0037 16.8 0.0 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 AJZ75573.1 - 0.011 15.3 0.0 0.031 13.9 0.0 1.8 1 1 0 1 1 1 0 Cytidylyltransferase Acetyltransf_1 PF00583.19 AJZ75574.1 - 1.1e-15 57.3 0.0 1.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AJZ75574.1 - 2.5e-15 56.4 0.1 3.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AJZ75574.1 - 9.8e-11 41.8 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AJZ75574.1 - 3.5e-08 33.3 0.0 3.8e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AJZ75574.1 - 5.9e-06 26.3 0.0 6.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AJZ75574.1 - 0.00039 20.5 0.0 0.00045 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AJZ75574.1 - 0.0022 17.8 0.2 0.005 16.6 0.1 1.6 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 AJZ75574.1 - 0.0039 16.9 0.0 0.014 15.1 0.0 1.9 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 AJZ75574.1 - 0.012 15.5 0.0 0.041 13.7 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RPAP3_C PF13877.1 AJZ75574.1 - 0.021 14.7 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Diacid_rec PF05651.8 AJZ75574.1 - 0.022 14.1 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Putative sugar diacid recognition B12D PF06522.6 AJZ75575.1 - 0.04 13.6 0.5 2.5 7.8 0.1 2.8 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit CcmE PF03100.10 AJZ75575.1 - 0.049 13.2 0.0 0.065 12.8 0.0 1.5 1 1 0 1 1 1 0 CcmE Cas_Csx9 PF09658.5 AJZ75575.1 - 0.19 10.5 0.6 0.23 10.1 0.1 1.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csx9) Claudin_2 PF13903.1 AJZ75575.1 - 0.24 11.0 4.8 1.8 8.2 3.3 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane_5 PF13346.1 AJZ75575.1 - 0.67 9.2 6.6 0.87 8.8 4.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2975 PF11188.3 AJZ75575.1 - 1.3 8.7 7.7 0.64 9.7 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) DUF423 PF04241.10 AJZ75575.1 - 4.6 7.2 9.6 0.24 11.3 0.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF423) DUF309 PF03745.9 AJZ75576.1 - 1e-19 69.7 0.5 1.5e-19 69.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF309) Ribosomal_S24e PF01282.14 AJZ75577.1 - 0.00049 19.8 0.1 0.00065 19.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S27 PF01599.14 AJZ75578.1 - 1.4e-17 63.1 3.7 1.8e-17 62.9 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27a Ribosomal_L37e PF01907.14 AJZ75578.1 - 0.00033 20.3 7.4 0.00044 19.9 4.7 1.5 1 1 1 2 2 2 1 Ribosomal protein L37e GCC2_GCC3 PF07699.8 AJZ75578.1 - 0.00082 18.9 1.1 0.001 18.6 0.8 1.2 1 0 0 1 1 1 1 GCC2 and GCC3 DZR PF12773.2 AJZ75578.1 - 0.0047 16.7 0.6 0.0061 16.3 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon DUF1451 PF07295.6 AJZ75578.1 - 0.014 15.1 0.6 0.014 15.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) IBR PF01485.16 AJZ75578.1 - 0.021 14.6 0.8 0.022 14.6 0.5 1.1 1 0 0 1 1 1 0 IBR domain zinc_ribbon_2 PF13240.1 AJZ75578.1 - 0.026 13.9 2.4 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 AJZ75578.1 - 0.027 14.1 5.8 0.15 11.7 3.3 2.2 1 1 1 2 2 2 0 Nudix N-terminal GFA PF04828.9 AJZ75578.1 - 0.032 14.1 3.3 0.055 13.4 0.1 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme C1_1 PF00130.17 AJZ75578.1 - 0.052 13.2 1.7 0.066 12.9 1.2 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.14 AJZ75578.1 - 0.056 13.1 0.3 0.06 13.0 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family YhfH PF14149.1 AJZ75578.1 - 0.075 12.8 4.2 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 YhfH-like protein A2L_zn_ribbon PF08792.5 AJZ75578.1 - 0.15 11.5 3.0 0.27 10.7 2.1 1.4 1 1 0 1 1 1 0 A2L zinc ribbon domain DUF2256 PF10013.4 AJZ75578.1 - 0.21 11.3 1.6 9.7 6.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-ribbon_3 PF13248.1 AJZ75578.1 - 0.25 10.6 4.7 0.71 9.1 3.3 1.7 1 1 0 1 1 1 0 zinc-ribbon domain DUF2072 PF09845.4 AJZ75578.1 - 0.32 10.9 2.7 0.4 10.6 1.8 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) OrfB_Zn_ribbon PF07282.6 AJZ75578.1 - 0.48 10.1 4.9 0.6 9.8 3.4 1.3 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2H2_3 PF13878.1 AJZ75578.1 - 0.67 9.5 6.6 1.9 8.0 0.6 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Auto_anti-p27 PF06677.7 AJZ75578.1 - 0.87 9.4 4.1 1.8 8.3 2.9 1.5 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-NADH-PPase PF09297.6 AJZ75578.1 - 3.9 7.0 6.6 24 4.5 4.6 2.1 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF4046 PF13255.1 AJZ75579.1 - 0.0012 17.6 0.5 0.0016 17.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4046) Plectin PF00681.15 AJZ75579.1 - 0.051 13.1 0.1 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Plectin repeat SprT-like PF10263.4 AJZ75579.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 SprT-like family THUMP PF02926.12 AJZ75580.1 - 1.8e-05 24.6 0.2 3.8e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 THUMP domain Rad50_zn_hook PF04423.9 AJZ75580.1 - 0.046 13.1 1.2 0.073 12.5 0.1 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif SRP54 PF00448.17 AJZ75581.1 - 3.8e-68 228.8 0.3 6.3e-68 228.0 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 AJZ75581.1 - 2.1e-30 105.0 2.1 5.4e-30 103.7 0.6 2.3 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.14 AJZ75581.1 - 1e-14 54.4 1.7 3.1e-14 52.8 1.2 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 AJZ75581.1 - 9.3e-09 34.9 0.6 4.5e-08 32.7 0.4 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 AJZ75581.1 - 0.00013 20.8 0.1 0.00034 19.4 0.1 1.6 1 0 0 1 1 1 1 ArgK protein MobB PF03205.9 AJZ75581.1 - 0.00022 20.9 0.7 0.00053 19.7 0.5 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 AJZ75581.1 - 0.00075 18.9 1.8 0.0043 16.5 1.2 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.15 AJZ75581.1 - 0.00087 18.9 0.1 0.0021 17.7 0.1 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 AJZ75581.1 - 0.0009 20.0 1.9 0.0036 18.1 0.2 2.8 3 1 0 3 3 2 1 AAA domain PduV-EutP PF10662.4 AJZ75581.1 - 0.0016 17.9 1.5 1.2 8.6 0.4 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation KTI12 PF08433.5 AJZ75581.1 - 0.0029 16.8 0.1 0.0059 15.8 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NTPase_1 PF03266.10 AJZ75581.1 - 0.0036 17.0 0.9 0.014 15.1 0.1 2.3 2 0 0 2 2 2 1 NTPase AAA_31 PF13614.1 AJZ75581.1 - 0.005 16.7 0.0 0.11 12.4 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 AJZ75581.1 - 0.0065 16.7 1.6 0.02 15.1 1.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AJZ75581.1 - 0.0079 16.1 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 AJZ75581.1 - 0.0085 15.8 0.7 0.042 13.5 0.2 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 AJZ75581.1 - 0.0093 15.5 0.1 0.017 14.6 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein LpxK PF02606.9 AJZ75581.1 - 0.012 14.6 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase 6PF2K PF01591.13 AJZ75581.1 - 0.021 13.9 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_30 PF13604.1 AJZ75581.1 - 0.028 14.0 0.1 0.072 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 AJZ75581.1 - 0.03 13.6 1.8 0.052 12.9 0.6 1.9 2 0 0 2 2 2 0 Thymidylate kinase AAA_10 PF12846.2 AJZ75581.1 - 0.033 13.6 0.3 0.047 13.1 0.2 1.4 1 1 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 AJZ75581.1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 AJZ75581.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.6 AJZ75581.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein ABC_tran PF00005.22 AJZ75581.1 - 0.064 13.5 0.2 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MipZ PF09140.6 AJZ75581.1 - 0.069 12.2 0.3 1.1 8.2 0.2 2.2 1 1 0 1 1 1 0 ATPase MipZ Mur_ligase_M PF08245.7 AJZ75581.1 - 0.093 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Mur ligase middle domain AAA PF00004.24 AJZ75581.1 - 0.13 12.4 0.5 0.55 10.4 0.1 2.4 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 AJZ75581.1 - 0.16 10.6 0.0 0.24 10.0 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.5 AJZ75581.1 - 0.19 10.9 1.5 1.3 8.1 0.3 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ATP_bind_4 PF01902.12 AJZ75582.1 - 1.5e-60 204.3 0.1 1.7e-60 204.1 0.1 1.0 1 0 0 1 1 1 1 ATP-binding region QueC PF06508.8 AJZ75582.1 - 0.0047 16.2 0.2 0.0099 15.1 0.1 1.6 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 AJZ75582.1 - 0.022 14.2 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.11 AJZ75582.1 - 0.071 11.6 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase eIF-5a PF01287.15 AJZ75583.1 - 3.3e-15 55.7 3.2 4.4e-15 55.3 2.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 AJZ75583.1 - 0.011 15.6 0.0 0.043 13.6 0.0 1.9 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain EFP PF01132.15 AJZ75583.1 - 0.06 13.0 0.1 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain HTH_24 PF13412.1 AJZ75584.1 - 1.9e-08 33.5 1.0 5.6e-08 32.0 0.7 1.9 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AJZ75584.1 - 6.6e-08 31.9 1.7 5.6e-07 28.9 1.2 2.3 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_12 PF08461.5 AJZ75584.1 - 4.3e-06 26.3 2.0 4.7e-06 26.2 0.3 1.9 3 0 0 3 3 3 1 Ribonuclease R winged-helix domain HTH_11 PF08279.7 AJZ75584.1 - 5.6e-05 22.7 0.5 0.00019 20.9 0.3 1.9 1 1 0 1 1 1 1 HTH domain HTH_Tnp_Tc3_2 PF01498.13 AJZ75584.1 - 0.00054 19.9 0.2 0.001 19.0 0.1 1.5 1 0 0 1 1 1 1 Transposase Penicillinase_R PF03965.11 AJZ75584.1 - 0.0012 18.9 0.1 0.0021 18.1 0.0 1.6 2 1 0 2 2 2 1 Penicillinase repressor HTH_20 PF12840.2 AJZ75584.1 - 0.0094 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF3369 PF11849.3 AJZ75584.1 - 0.018 15.0 0.1 0.19 11.6 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3369) HTH_DeoR PF08220.7 AJZ75584.1 - 0.024 14.1 0.3 0.05 13.1 0.2 1.6 1 1 0 1 1 1 0 DeoR-like helix-turn-helix domain Myb_DNA-bind_4 PF13837.1 AJZ75584.1 - 0.066 13.3 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain FUR PF01475.14 AJZ75584.1 - 0.066 13.1 0.4 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Ferric uptake regulator family DUF2203 PF09969.4 AJZ75584.1 - 0.076 13.2 0.1 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Response_reg PF00072.19 AJZ75585.1 - 1.3e-14 54.1 0.4 2.8e-13 49.8 0.1 2.3 2 0 0 2 2 2 1 Response regulator receiver domain Apc3 PF12895.2 AJZ75585.1 - 0.00033 20.7 6.1 0.023 14.7 1.4 2.4 1 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.7 AJZ75585.1 - 0.00051 19.6 0.9 0.00091 18.8 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF627) TPR_2 PF07719.12 AJZ75585.1 - 0.012 15.4 0.3 0.048 13.6 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 AJZ75585.1 - 0.023 14.2 0.5 0.023 14.2 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ75585.1 - 0.062 13.1 0.8 0.35 10.7 0.5 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat PK_C PF02887.11 AJZ75585.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain TPR_21 PF09976.4 AJZ75585.1 - 0.13 12.1 6.0 0.76 9.7 3.9 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat PHO4 PF01384.15 AJZ75586.1 - 1.8e-93 312.7 41.1 2.2e-93 312.4 28.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family Myc_target_1 PF15179.1 AJZ75586.1 - 0.057 13.0 0.5 0.057 13.0 0.3 1.7 2 0 0 2 2 2 0 Myc target protein 1 HTH_IclR PF09339.5 AJZ75586.1 - 0.073 12.6 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain PhoU_div PF01865.11 AJZ75587.1 - 2.5e-27 95.4 12.5 3.1e-27 95.1 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 ACCA PF03255.9 AJZ75587.1 - 0.00032 20.2 2.9 0.0019 17.7 0.2 2.3 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Lzipper-MIP1 PF14389.1 AJZ75587.1 - 0.00078 19.4 0.7 1.2 9.2 0.0 3.1 3 0 0 3 3 3 2 Leucine-zipper of ternary complex factor MIP1 PhoU PF01895.14 AJZ75587.1 - 0.002 18.5 14.0 0.065 13.6 1.4 2.5 2 1 0 2 2 2 2 PhoU domain Vps5 PF09325.5 AJZ75587.1 - 0.0088 15.3 0.9 1.6 7.8 0.0 2.5 2 1 1 3 3 3 2 Vps5 C terminal like TMF_TATA_bd PF12325.3 AJZ75587.1 - 0.0099 15.6 1.5 0.0099 15.6 1.0 1.9 2 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DXP_synthase_N PF13292.1 AJZ75587.1 - 0.02 13.8 0.2 0.046 12.6 0.1 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase CENP-R PF06729.7 AJZ75587.1 - 0.056 13.1 0.6 0.1 12.2 0.4 1.5 1 0 0 1 1 1 0 Kinetochore component, CENP-R Sec2p PF06428.6 AJZ75587.1 - 0.07 12.9 0.5 0.07 12.9 0.3 2.0 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF3571 PF12095.3 AJZ75587.1 - 0.086 13.0 1.7 0.23 11.6 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3571) Mer2 PF09074.5 AJZ75587.1 - 0.099 12.5 3.3 0.21 11.4 0.3 2.2 2 0 0 2 2 2 0 Mer2 DUF552 PF04472.7 AJZ75587.1 - 0.1 12.5 1.2 0.33 10.9 0.0 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF552) XendoU PF09412.5 AJZ75587.1 - 0.12 11.4 0.3 0.21 10.5 0.2 1.4 1 0 0 1 1 1 0 Endoribonuclease XendoU DUF972 PF06156.8 AJZ75587.1 - 0.48 10.7 2.5 2.6 8.4 0.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 AJZ75587.1 - 3.6 7.7 9.7 48 4.1 1.9 3.6 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 P-II PF00543.17 AJZ75588.1 - 1.4e-20 73.7 1.6 1.6e-20 73.4 1.1 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II P-II PF00543.17 AJZ75589.1 - 6.3e-10 39.4 1.3 1e-09 38.7 0.7 1.5 2 0 0 2 2 2 1 Nitrogen regulatory protein P-II ADH_N PF08240.7 AJZ75590.1 - 3.5e-36 123.2 1.2 5.8e-36 122.5 0.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AJZ75590.1 - 2.2e-33 114.5 0.2 3.4e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AJZ75590.1 - 1.4e-10 42.1 0.0 2.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_16 PF10294.4 AJZ75590.1 - 0.0056 16.1 0.2 0.0089 15.4 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase DapB_N PF01113.15 AJZ75590.1 - 0.0057 16.5 0.5 0.011 15.5 0.3 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 AJZ75590.1 - 0.022 14.7 0.1 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 AJZ75590.1 - 0.026 14.1 0.2 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 AJZ75590.1 - 0.055 13.3 0.5 0.085 12.6 0.3 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MTS PF05175.9 AJZ75590.1 - 0.089 12.1 0.2 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Malic_M PF03949.10 AJZ75590.1 - 0.12 11.9 1.9 0.94 8.9 0.4 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NADH_4Fe-4S PF10589.4 AJZ75590.1 - 0.23 10.6 1.9 0.47 9.6 1.3 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region ScpA_ScpB PF02616.9 AJZ75591.1 - 1.2e-14 54.4 4.3 3.2e-07 30.1 0.6 2.2 1 1 0 2 2 2 2 ScpA/B protein DUF387 PF04079.11 AJZ75592.1 - 9.4e-34 116.0 0.3 1.1e-33 115.8 0.2 1.0 1 0 0 1 1 1 1 Putative transcriptional regulators (Ypuh-like) HTH_20 PF12840.2 AJZ75592.1 - 0.012 15.3 0.1 0.09 12.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HHH_3 PF12836.2 AJZ75592.1 - 0.067 13.1 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif Ribosomal_S8e PF01201.17 AJZ75593.1 - 3.2e-21 75.8 3.7 3.5e-21 75.7 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SRP19 PF01922.12 AJZ75594.1 - 2.2e-17 63.4 0.0 2.6e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 SRP19 protein TFIIB PF00382.14 AJZ75595.1 - 8.3e-27 92.8 2.2 5.4e-13 48.5 0.2 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJZ75595.1 - 5.4e-09 35.2 2.3 5.4e-09 35.2 1.6 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding Auto_anti-p27 PF06677.7 AJZ75595.1 - 0.041 13.6 2.3 0.041 13.6 1.6 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Cyclin_N PF00134.18 AJZ75595.1 - 0.077 12.5 0.5 0.25 10.9 0.1 1.9 1 1 1 2 2 2 0 Cyclin, N-terminal domain DZR PF12773.2 AJZ75595.1 - 1.2 8.9 6.1 0.29 10.9 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon ABC_tran PF00005.22 AJZ75596.1 - 3.6e-21 75.8 0.0 5.4e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJZ75596.1 - 3.7e-11 43.5 0.1 7.9e-10 39.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 AJZ75596.1 - 1.1e-09 37.8 0.4 1.8e-08 33.8 0.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 AJZ75596.1 - 0.00012 21.5 0.0 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AJZ75596.1 - 0.00065 19.1 0.1 0.0018 17.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 AJZ75596.1 - 0.0014 18.4 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.1 AJZ75596.1 - 0.0063 15.0 0.3 0.14 10.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 AJZ75596.1 - 0.01 16.1 0.6 0.021 15.1 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AJZ75596.1 - 0.014 15.3 0.1 0.1 12.4 0.0 2.2 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AJZ75596.1 - 0.02 14.9 0.1 0.059 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain MutS_V PF00488.16 AJZ75596.1 - 0.021 14.2 0.0 4 6.7 0.0 2.2 2 0 0 2 2 2 0 MutS domain V RNA_helicase PF00910.17 AJZ75596.1 - 0.024 14.7 0.0 0.5 10.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 AJZ75596.1 - 0.028 14.1 0.0 0.07 12.8 0.0 1.6 1 1 1 2 2 2 0 Archaeal ATPase AAA PF00004.24 AJZ75596.1 - 0.03 14.5 0.3 0.7 10.1 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 AJZ75596.1 - 0.037 13.2 0.0 0.081 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Adeno_IVa2 PF02456.10 AJZ75596.1 - 0.049 12.2 0.0 0.094 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_17 PF13207.1 AJZ75596.1 - 0.05 14.4 0.3 0.12 13.1 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AJZ75596.1 - 0.068 13.3 0.1 0.18 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain ANF_receptor PF01094.23 AJZ75596.1 - 0.075 11.8 0.0 1.4 7.6 0.0 2.1 2 1 0 2 2 2 0 Receptor family ligand binding region ArgK PF03308.11 AJZ75596.1 - 0.095 11.4 0.1 0.16 10.7 0.1 1.3 1 0 0 1 1 1 0 ArgK protein T2SE PF00437.15 AJZ75596.1 - 0.13 11.1 0.1 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 AJZ75596.1 - 0.16 12.3 0.3 2.6 8.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF167 PF02594.11 AJZ75597.1 - 7.9e-15 54.5 0.3 8.5e-15 54.4 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 SpoIIIAH PF12685.2 AJZ75597.1 - 0.055 12.9 0.0 0.066 12.6 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Chlor_dismutase PF06778.7 AJZ75598.1 - 6.1e-53 179.4 0.4 7.3e-53 179.1 0.2 1.0 1 0 0 1 1 1 1 Chlorite dismutase DUF1684 PF07920.6 AJZ75598.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) Aldo_ket_red PF00248.16 AJZ75599.1 - 1.1e-50 172.0 0.0 1.3e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Vac_Fusion PF02346.11 AJZ75600.1 - 0.034 13.5 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus fusion protein Acyl_transf_3 PF01757.17 AJZ75601.1 - 0.078 11.7 21.6 0.3 9.8 14.9 1.8 1 1 0 1 1 1 0 Acyltransferase family DUF3366 PF11846.3 AJZ75601.1 - 2.8 7.7 7.5 0.45 10.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) HTH_AsnC-type PF13404.1 AJZ75602.1 - 6.3e-06 25.6 0.0 0.00092 18.6 0.0 2.5 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.16 AJZ75602.1 - 0.00038 20.0 0.0 1.1 8.9 0.0 3.2 2 1 0 2 2 2 2 AsnC family HTH_24 PF13412.1 AJZ75602.1 - 0.01 15.2 0.2 0.091 12.1 0.1 2.4 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding GlutR_N PF05201.10 AJZ75603.1 - 5.1e-43 146.2 0.1 1.1e-42 145.1 0.0 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.15 AJZ75603.1 - 2.3e-24 86.0 0.1 5.4e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.15 AJZ75603.1 - 1.9e-21 75.8 2.7 3.8e-21 74.9 1.9 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.12 AJZ75603.1 - 0.00046 20.5 0.0 0.0014 18.9 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 AJZ75603.1 - 0.0014 17.8 0.1 0.0031 16.7 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 AJZ75603.1 - 0.0083 16.1 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_7 PF13241.1 AJZ75603.1 - 0.022 14.9 0.0 0.061 13.5 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding ALAD PF00490.16 AJZ75604.1 - 1.5e-135 451.3 0.2 1.7e-135 451.1 0.1 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF872 PF05915.7 AJZ75607.1 - 0.0094 15.7 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Neurensin PF14927.1 AJZ75607.1 - 0.012 15.0 0.1 0.08 12.3 0.0 2.1 2 0 0 2 2 2 0 Neurensin DUF2371 PF10177.4 AJZ75607.1 - 0.025 14.4 0.1 0.054 13.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) NfeD PF01957.13 AJZ75607.1 - 0.055 13.6 1.4 0.36 10.9 0.1 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding ABC2_membrane_4 PF12730.2 AJZ75607.1 - 0.086 11.9 5.0 0.22 10.6 3.5 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3040 PF11239.3 AJZ75607.1 - 0.093 12.7 0.3 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) TMEM154 PF15102.1 AJZ75607.1 - 0.15 11.7 1.9 0.31 10.7 1.3 1.6 1 1 0 1 1 1 0 TMEM154 protein family SdpI PF13630.1 AJZ75607.1 - 0.16 11.6 5.0 1.3 8.8 1.5 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family Pox_A14 PF05767.7 AJZ75607.1 - 0.41 10.6 2.9 0.73 9.8 0.7 2.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF3098 PF11297.3 AJZ75607.1 - 2.8 7.7 8.0 2.2 8.0 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) DUF1628 PF07790.6 AJZ75607.1 - 8.7 7.1 7.7 1.7 9.4 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1628) PAP2 PF01569.16 AJZ75609.1 - 1e-19 70.4 0.4 1e-19 70.4 0.2 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 AJZ75609.1 - 1.8e-06 27.6 0.6 5.4e-06 26.0 0.4 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 AJZ75609.1 - 4.9e-06 26.7 3.8 1.4e-05 25.2 0.0 2.8 3 0 0 3 3 3 1 PAP2 superfamily C-terminal NifU_N PF01592.11 AJZ75611.1 - 4.8e-27 94.4 0.0 5.7e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Aminotran_5 PF00266.14 AJZ75612.1 - 5.8e-149 495.8 0.9 6.6e-149 495.6 0.6 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AJZ75612.1 - 2e-05 23.8 0.1 3.7e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Alpha-amylase PF00128.19 AJZ75612.1 - 0.0016 17.8 0.9 1.6 8.0 0.0 2.8 3 0 0 3 3 3 2 Alpha amylase, catalytic domain Cys_Met_Meta_PP PF01053.15 AJZ75612.1 - 0.003 15.9 0.0 0.0049 15.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SelA PF03841.8 AJZ75612.1 - 0.0066 15.2 0.1 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase CYTL1 PF15153.1 AJZ75612.1 - 0.0076 15.9 0.1 2.9 7.5 0.0 2.4 2 0 0 2 2 2 2 Cytokine-like protein 1 DegT_DnrJ_EryC1 PF01041.12 AJZ75612.1 - 0.04 12.9 0.1 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4582 PF15189.1 AJZ75612.1 - 0.056 12.6 0.8 0.11 11.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4582) Rieske PF00355.21 AJZ75613.1 - 5.8e-17 61.0 0.0 6.4e-17 60.9 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AJZ75613.1 - 6.1e-12 45.1 0.0 6.9e-12 45.0 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0051 PF01458.12 AJZ75614.1 - 2.1e-59 200.7 0.7 2.6e-59 200.4 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) TfuA PF07812.7 AJZ75614.1 - 0.064 12.7 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 0 TfuA-like protein UPF0051 PF01458.12 AJZ75615.1 - 3.5e-69 232.7 0.2 4.6e-69 232.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Pico_P1A PF02226.11 AJZ75615.1 - 0.16 11.7 1.3 5.1 6.9 0.1 3.2 3 0 0 3 3 3 0 Picornavirus coat protein (VP4) HEM4 PF02602.10 AJZ75616.1 - 7.1e-42 143.2 0.0 8.1e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD YIEGIA PF14045.1 AJZ75616.1 - 0.036 12.7 0.0 0.36 9.4 0.0 2.1 1 1 0 2 2 2 0 YIEGIA protein TP_methylase PF00590.15 AJZ75617.1 - 8.7e-44 149.7 0.0 1e-43 149.5 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NPL4 PF05021.10 AJZ75617.1 - 0.11 11.6 0.1 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 NPL4 family Porphobil_deam PF01379.15 AJZ75618.1 - 1.7e-72 242.7 0.0 2.2e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 AJZ75618.1 - 4.9e-11 42.5 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Aminotran_3 PF00202.16 AJZ75619.1 - 2e-68 230.7 0.4 3e-68 230.1 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-III z-alpha PF02295.12 AJZ75619.1 - 0.16 11.7 0.1 0.38 10.5 0.1 1.6 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain ABC2_membrane PF01061.19 AJZ75620.1 - 1.7e-34 118.8 20.8 1.7e-34 118.8 14.4 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 AJZ75620.1 - 8.2e-19 67.8 30.7 1.1e-18 67.4 21.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 AJZ75620.1 - 1.6e-08 34.0 29.2 3.8e-08 32.7 20.0 1.6 1 1 1 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 AJZ75620.1 - 3.8e-06 25.9 29.7 1.8e-05 23.7 20.6 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 AJZ75621.1 - 1e-30 106.7 0.0 4.6e-30 104.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 AJZ75621.1 - 5.2e-14 52.8 2.2 6e-10 39.5 0.2 2.3 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 AJZ75621.1 - 1.7e-06 27.3 1.4 1.5e-05 24.2 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 AJZ75621.1 - 5.8e-05 22.5 0.1 0.00012 21.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4162 PF13732.1 AJZ75621.1 - 8e-05 23.0 0.0 0.00021 21.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_23 PF13476.1 AJZ75621.1 - 0.001 19.4 3.3 0.0022 18.3 2.3 1.9 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 AJZ75621.1 - 0.0057 15.9 0.2 0.57 9.3 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 AJZ75621.1 - 0.0085 15.5 0.4 0.07 12.5 0.2 2.0 1 1 1 2 2 2 1 AAA-like domain RRM_6 PF14259.1 AJZ75621.1 - 0.016 15.2 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_30 PF13604.1 AJZ75621.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 AJZ75621.1 - 0.059 13.3 0.0 0.57 10.1 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 AJZ75621.1 - 0.06 12.1 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 AJZ75621.1 - 0.095 12.8 0.5 1.7 8.7 0.4 2.3 1 1 0 1 1 1 0 AAA domain DUF385 PF04075.9 AJZ75622.1 - 7e-08 32.5 0.2 8.8e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF385) DUF2255 PF10012.4 AJZ75622.1 - 0.0084 16.0 0.2 0.01 15.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2255) HTH_Tnp_Tc5 PF03221.11 AJZ75623.1 - 0.0013 18.5 0.1 0.0021 17.8 0.1 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Acetyltransf_1 PF00583.19 AJZ75626.1 - 1.4e-15 57.0 0.0 1.8e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AJZ75626.1 - 1.5e-10 41.0 0.0 1.9e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AJZ75626.1 - 3.1e-09 36.9 0.0 3.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AJZ75626.1 - 2.9e-07 30.5 0.0 3.4e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 AJZ75626.1 - 0.00027 20.5 0.0 0.00031 20.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AJZ75626.1 - 0.0068 16.2 0.0 0.0078 16.1 0.0 1.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AJZ75626.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 AJZ75626.1 - 0.018 14.8 0.0 0.035 13.9 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PLDc_2 PF13091.1 AJZ75627.1 - 4.5e-06 26.4 0.1 6e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 PLD-like domain DUF1391 PF07151.7 AJZ75627.1 - 0.068 12.6 0.5 0.37 10.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1391) tRNA_int_endo PF01974.12 AJZ75628.1 - 2.2e-18 65.8 0.1 4.2e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 AJZ75628.1 - 8.8e-12 44.4 2.9 1.3e-10 40.6 0.1 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain tRNA_int_end_N2 PF12928.2 AJZ75628.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term Sigma70_r3 PF04539.11 AJZ75629.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.6 2 0 0 2 2 2 1 Sigma-70 region 3 Na_H_Exchanger PF00999.16 AJZ75631.1 - 7.4e-60 202.4 58.1 9.1e-60 202.1 40.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AAA_22 PF13401.1 AJZ75632.1 - 0.011 15.8 1.4 0.72 10.0 0.0 3.2 2 1 1 4 4 4 0 AAA domain DUF2791 PF10923.3 AJZ75632.1 - 0.014 14.0 0.1 0.027 13.0 0.1 1.4 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) NACHT PF05729.7 AJZ75632.1 - 0.058 13.0 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DUF1664 PF07889.7 AJZ75635.1 - 0.00021 21.1 29.7 0.0012 18.6 0.4 4.9 1 1 3 4 4 4 1 Protein of unknown function (DUF1664) Laminin_II PF06009.7 AJZ75635.1 - 0.0016 18.1 41.8 0.0039 16.9 1.1 4.5 2 1 2 5 5 5 3 Laminin Domain II TMF_TATA_bd PF12325.3 AJZ75635.1 - 0.0018 17.9 0.4 0.0018 17.9 0.3 4.5 2 2 2 4 4 4 1 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.1 AJZ75635.1 - 0.027 14.5 14.1 0.075 13.1 1.9 3.8 3 2 1 4 4 4 0 Domain of unknown function (DUF4164) GAS PF13851.1 AJZ75635.1 - 0.12 11.5 34.4 0.035 13.3 6.5 4.0 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Cauli_AT PF03233.8 AJZ75635.1 - 0.17 11.5 34.4 0.02 14.6 3.2 4.7 1 1 3 5 5 5 0 Aphid transmission protein Reo_sigmaC PF04582.7 AJZ75635.1 - 0.43 9.7 32.2 0.47 9.5 2.0 3.8 1 1 1 3 3 3 0 Reovirus sigma C capsid protein MCPsignal PF00015.16 AJZ75635.1 - 0.81 9.1 36.5 0.35 10.3 1.3 4.4 1 1 3 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TBCA PF02970.11 AJZ75635.1 - 1.2 9.2 17.9 0.26 11.3 1.3 3.6 4 1 0 4 4 4 0 Tubulin binding cofactor A eIF3_N PF09440.5 AJZ75635.1 - 1.5 8.9 22.4 1.3 9.2 1.1 4.5 2 2 2 4 4 4 0 eIF3 subunit 6 N terminal domain Sec34 PF04136.10 AJZ75635.1 - 1.8 8.2 23.4 0.17 11.6 0.3 4.6 2 2 1 4 4 4 0 Sec34-like family DUF869 PF05911.6 AJZ75635.1 - 3.4 5.7 39.2 0.19 9.9 17.2 2.1 1 1 0 2 2 2 0 Plant protein of unknown function (DUF869) Cob_adeno_trans PF01923.13 AJZ75635.1 - 3.5 7.3 16.3 0.95 9.2 0.1 4.2 1 1 2 5 5 5 0 Cobalamin adenosyltransferase NPV_P10 PF05531.7 AJZ75635.1 - 4.4 7.6 32.9 11 6.3 4.3 6.0 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 AJZ75635.1 - 9.2 6.3 38.2 2.8 8.0 2.5 4.0 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family MCPsignal PF00015.16 AJZ75636.1 - 1.2e-51 175.3 56.7 1.5e-47 161.9 25.5 3.3 2 1 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.20 AJZ75636.1 - 6.5e-13 48.6 8.0 1.5e-11 44.2 0.0 4.9 4 2 0 4 4 4 1 HAMP domain CheZ PF04344.8 AJZ75636.1 - 0.00073 19.2 2.1 0.00073 19.2 1.5 3.4 1 1 2 4 4 4 1 Chemotaxis phosphatase, CheZ DUF745 PF05335.8 AJZ75636.1 - 0.0047 16.4 5.1 0.0047 16.4 3.6 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF745) Coat_F PF07875.7 AJZ75636.1 - 0.78 9.9 3.8 0.94 9.6 0.1 3.0 3 0 0 3 3 3 0 Coat F domain Laminin_II PF06009.7 AJZ75636.1 - 2 8.1 39.6 0.11 12.2 3.0 4.4 1 1 3 4 4 4 0 Laminin Domain II Chlorosome_CsmC PF11098.3 AJZ75636.1 - 2.7 7.7 14.7 2.8 7.6 0.8 4.0 1 1 4 5 5 5 0 Chlorosome envelope protein C DUF948 PF06103.6 AJZ75636.1 - 4.5 7.1 33.3 1.9 8.4 1.6 5.8 3 2 2 7 7 7 0 Bacterial protein of unknown function (DUF948) Glyco_tranf_2_3 PF13641.1 AJZ75637.1 - 1.6e-36 126.2 0.1 2.4e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 AJZ75637.1 - 1e-23 84.0 0.5 1e-23 84.0 0.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 AJZ75637.1 - 1.2e-16 60.8 0.1 2.3e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AJZ75637.1 - 1.5e-13 50.3 1.0 2.3e-13 49.8 0.1 1.7 1 1 1 2 2 2 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 AJZ75637.1 - 0.003 15.9 1.9 0.031 12.5 0.2 2.1 2 0 0 2 2 2 1 Cellulose synthase Glyco_tranf_2_2 PF10111.4 AJZ75637.1 - 0.0037 16.3 0.0 0.0075 15.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 AJZ75637.1 - 0.052 13.8 0.5 0.44 10.8 0.3 2.7 3 0 0 3 3 3 0 Glycosyl transferase family 2 Fer4 PF00037.22 AJZ75638.1 - 2.1e-08 33.4 15.3 6.4e-05 22.3 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AJZ75638.1 - 1.5e-06 28.4 5.5 3.6e-06 27.2 3.9 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AJZ75638.1 - 2.4e-06 27.7 5.8 4.4e-06 26.8 4.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AJZ75638.1 - 1.1e-05 25.1 6.1 2.2e-05 24.1 4.2 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AJZ75638.1 - 0.00012 21.8 4.0 0.0002 21.1 2.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 AJZ75638.1 - 0.00019 21.1 15.4 0.0012 18.6 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 AJZ75638.1 - 0.001 19.4 3.3 0.71 10.3 0.4 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 AJZ75638.1 - 0.0029 17.4 12.2 0.011 15.6 1.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 AJZ75638.1 - 0.0047 17.1 6.9 0.17 12.2 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 AJZ75638.1 - 0.005 16.8 6.0 0.064 13.2 5.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 AJZ75638.1 - 0.45 11.1 9.4 0.83 10.2 0.5 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_17 PF13534.1 AJZ75638.1 - 0.46 10.8 5.8 8.4 6.8 0.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 AJZ75638.1 - 0.55 11.0 8.3 4.1 8.2 1.3 2.7 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 AJZ75638.1 - 0.59 10.8 15.1 1.1 10.0 1.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.1 AJZ75638.1 - 1.5 9.2 9.0 1.4 9.3 0.6 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain NAD_binding_1 PF00175.16 AJZ75639.1 - 3.5e-13 50.0 0.0 8.1e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AJZ75639.1 - 3.2e-10 40.0 0.0 5.3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AJZ75639.1 - 0.011 15.6 0.1 0.027 14.3 0.0 1.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain ISG65-75 PF11727.3 AJZ75640.1 - 0.22 10.5 10.4 0.15 11.1 5.7 1.6 2 0 0 2 2 2 0 Invariant surface glycoprotein TPR_MLP1_2 PF07926.7 AJZ75640.1 - 2.5 7.8 10.2 35 4.1 5.9 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3391 PF11871.3 AJZ75640.1 - 6.9 6.8 8.4 7 6.8 3.9 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Fer4 PF00037.22 AJZ75641.1 - 2.9e-08 32.9 15.2 9.4e-05 21.8 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AJZ75641.1 - 3.4e-06 27.3 5.7 9.3e-06 25.9 4.0 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AJZ75641.1 - 5.3e-06 26.6 5.3 1.1e-05 25.5 3.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AJZ75641.1 - 5.6e-06 26.0 5.0 1.1e-05 25.1 3.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AJZ75641.1 - 9e-05 22.2 4.2 0.00014 21.5 2.9 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 AJZ75641.1 - 0.00056 19.6 15.1 0.0038 17.0 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 AJZ75641.1 - 0.0016 18.8 3.6 0.72 10.3 0.5 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 AJZ75641.1 - 0.0023 17.7 11.9 0.011 15.6 1.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 AJZ75641.1 - 0.0031 17.4 5.7 0.017 15.1 4.4 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 AJZ75641.1 - 0.0054 16.9 6.4 0.23 11.8 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 AJZ75641.1 - 0.16 12.5 8.1 0.59 10.7 0.3 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_17 PF13534.1 AJZ75641.1 - 0.37 11.1 5.4 9 6.7 0.0 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.2 AJZ75641.1 - 0.54 10.9 14.8 1 10.0 1.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_16 PF13484.1 AJZ75641.1 - 0.63 10.8 8.7 3.6 8.4 1.2 3.0 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain NAD_kinase PF01513.16 AJZ75643.1 - 5.1e-32 110.7 1.4 7.4e-32 110.2 1.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 AJZ75643.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain BTB_2 PF02214.17 AJZ75643.1 - 0.0081 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CoA_binding_2 PF13380.1 AJZ75643.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 CoA binding domain WTX PF09422.5 AJZ75643.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 WTX protein NOB1_Zn_bind PF08772.6 AJZ75644.1 - 2.1e-05 24.2 0.4 3.8e-05 23.4 0.3 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF3279 PF11682.3 AJZ75644.1 - 0.0032 17.0 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3279) zf-ribbon_3 PF13248.1 AJZ75644.1 - 0.0032 16.6 5.2 0.0052 15.9 3.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain UPF0278 PF08745.6 AJZ75644.1 - 0.0043 16.3 0.3 0.015 14.5 0.1 1.7 1 1 0 2 2 2 1 UPF0278 family PIN PF01850.16 AJZ75644.1 - 0.0061 16.8 0.2 0.0077 16.5 0.1 1.2 1 0 0 1 1 1 1 PIN domain Nudix_N_2 PF14803.1 AJZ75644.1 - 0.015 14.9 0.0 0.015 14.9 0.0 2.1 2 1 1 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 AJZ75644.1 - 0.019 14.4 0.8 0.048 13.1 0.6 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 AJZ75644.1 - 0.023 14.4 0.1 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 zinc-ribbons DUF1272 PF06906.6 AJZ75644.1 - 0.026 14.3 0.5 0.041 13.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_ribbon_recom PF13408.1 AJZ75644.1 - 0.033 14.4 0.2 0.055 13.7 0.1 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain RNA_POL_M_15KD PF02150.11 AJZ75644.1 - 0.096 12.3 0.6 0.2 11.3 0.4 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Sar8_2 PF03058.9 AJZ75644.1 - 0.11 12.8 0.2 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Sar8.2 family Phage-MuB_C PF09077.6 AJZ75644.1 - 0.14 11.8 0.7 1.3 8.7 0.1 2.2 1 1 0 2 2 2 0 Mu B transposition protein, C terminal zf-LITAF-like PF10601.4 AJZ75644.1 - 0.17 11.7 2.2 7.6 6.4 2.2 2.2 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Rhodanese PF00581.15 AJZ75645.1 - 2.6e-39 134.0 0.0 2.3e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain ERCC4 PF02732.10 AJZ75646.1 - 1e-26 93.3 0.0 1.6e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH PF00633.18 AJZ75646.1 - 2.1e-07 30.2 0.4 0.011 15.4 0.1 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 AJZ75646.1 - 4.7e-07 29.8 0.0 1.8e-06 27.9 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.2 AJZ75646.1 - 2.3e-06 27.3 0.0 1.7e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.2 AJZ75646.1 - 0.00066 19.5 0.1 0.22 11.4 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_8 PF14716.1 AJZ75646.1 - 0.0011 19.0 0.3 0.28 11.4 0.1 2.5 1 1 1 2 2 2 2 Helix-hairpin-helix domain Transposase_20 PF02371.11 AJZ75646.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.3 AJZ75646.1 - 0.052 13.6 0.2 1.1 9.4 0.0 2.7 3 0 0 3 3 3 0 IMS family HHH motif DUF3701 PF12482.3 AJZ75646.1 - 0.056 13.1 0.0 0.85 9.4 0.0 2.2 1 1 1 2 2 2 0 Phage integrase protein Prefoldin_2 PF01920.15 AJZ75647.1 - 4.6e-22 77.7 17.8 5.2e-22 77.6 12.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF3053 PF11254.3 AJZ75647.1 - 0.0074 15.5 4.5 0.011 15.0 3.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3053) SBP_bac_3 PF00497.15 AJZ75647.1 - 0.015 14.5 0.6 0.018 14.3 0.4 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Lipoprotein_7 PF01540.11 AJZ75647.1 - 0.065 12.2 4.6 0.1 11.6 3.2 1.3 1 1 0 1 1 1 0 Adhesin lipoprotein ArsA_ATPase PF02374.10 AJZ75647.1 - 0.21 10.5 4.0 0.34 9.8 2.8 1.4 1 1 0 1 1 1 0 Anion-transporting ATPase AF0941-like PF14591.1 AJZ75647.1 - 1.3 9.1 8.7 5.7 7.0 1.8 2.1 1 1 1 2 2 2 0 AF0941-like Sld5 PF05916.6 AJZ75647.1 - 1.7 8.9 5.5 3 8.1 3.8 1.6 1 1 0 1 1 1 0 GINS complex protein Vir_act_alpha_C PF10400.4 AJZ75647.1 - 1.8 8.9 6.1 1.8 8.9 0.4 2.2 2 0 0 2 2 2 0 Virulence activator alpha C-term SNAPc19 PF15497.1 AJZ75647.1 - 3.5 7.8 12.0 17 5.6 8.3 2.0 1 1 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Nup88 PF10168.4 AJZ75647.1 - 6.8 4.3 10.9 8.3 4.1 7.5 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF919 PF06034.6 AJZ75647.1 - 9 5.9 11.1 0.53 9.9 2.4 2.5 2 2 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Pcc1 PF09341.5 AJZ75648.1 - 3.4e-09 36.6 0.2 3.9e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF4415 PF14384.1 AJZ75648.1 - 0.034 14.3 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4415) UPF0262 PF06793.7 AJZ75648.1 - 0.04 13.6 0.1 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Ribosomal_L37ae PF01780.14 AJZ75649.1 - 2.4e-15 56.1 4.1 2.6e-15 56.0 2.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.17 AJZ75649.1 - 0.0016 18.1 1.9 0.002 17.8 1.3 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RRN7 PF11781.3 AJZ75649.1 - 0.003 17.0 0.7 0.004 16.6 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_2 PF13240.1 AJZ75649.1 - 0.0056 16.1 1.8 1.5 8.3 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 AJZ75649.1 - 0.0062 16.3 2.4 0.0062 16.3 1.7 1.7 2 0 0 2 2 2 1 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 AJZ75649.1 - 0.011 15.3 1.7 0.014 15.0 1.2 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-RanBP PF00641.13 AJZ75649.1 - 0.025 13.6 4.3 1.4 8.0 0.2 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DZR PF12773.2 AJZ75649.1 - 0.03 14.1 1.3 0.053 13.3 0.9 1.4 1 1 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 AJZ75649.1 - 0.057 12.9 2.3 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.1 AJZ75649.1 - 0.06 12.5 2.0 6.3 6.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.11 AJZ75649.1 - 0.16 11.6 3.4 0.76 9.5 2.1 1.9 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C2H2_3 PF13878.1 AJZ75649.1 - 0.22 11.1 2.7 3 7.4 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO YhfH PF14149.1 AJZ75649.1 - 0.28 11.0 4.2 4.8 7.0 0.5 2.2 2 0 0 2 2 2 0 YhfH-like protein Zn-ribbon_8 PF09723.5 AJZ75649.1 - 0.32 10.9 1.7 5.8 6.9 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain FeS PF04060.8 AJZ75649.1 - 0.69 9.5 3.0 3.3 7.3 0.3 2.2 2 0 0 2 2 2 0 Putative Fe-S cluster zf-tcix PF14952.1 AJZ75649.1 - 2.8 7.3 8.5 4.2 6.7 1.1 2.4 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding RNase_PH PF01138.16 AJZ75650.1 - 4.3e-24 85.2 0.0 7.5e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AJZ75650.1 - 7.1e-16 57.9 0.1 1.7e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.16 AJZ75651.1 - 9.8e-33 113.2 0.0 1.3e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AJZ75651.1 - 4.4e-13 48.9 0.3 8.2e-13 48.0 0.2 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KH_1 PF00013.24 AJZ75652.1 - 5.2e-11 42.0 1.6 1.1e-10 40.9 1.1 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 AJZ75652.1 - 0.00019 20.9 0.4 0.00049 19.6 0.3 1.7 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 AJZ75652.1 - 0.0017 17.8 0.5 0.0036 16.8 0.4 1.5 1 0 0 1 1 1 1 KH domain Prim-Pol PF09250.6 AJZ75652.1 - 0.017 15.1 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal KH_4 PF13083.1 AJZ75652.1 - 0.029 14.0 0.1 0.078 12.6 0.1 1.8 1 1 0 1 1 1 0 KH domain ECR1_N PF14382.1 AJZ75652.1 - 0.14 11.4 0.1 0.3 10.4 0.1 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region SBDS PF01172.13 AJZ75653.1 - 6.2e-26 90.0 0.3 1.1e-25 89.2 0.2 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 AJZ75653.1 - 3.4e-22 78.4 0.1 7.1e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain EFG_C PF00679.19 AJZ75653.1 - 0.0088 15.8 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus DUF2760 PF10816.3 AJZ75653.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) RNA_pol_A_bac PF01000.21 AJZ75654.1 - 1e-25 90.0 0.0 1.6e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AJZ75654.1 - 8e-13 47.3 0.0 9.7e-13 47.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.1 AJZ75654.1 - 0.097 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L13 PF00572.13 AJZ75655.1 - 4e-23 81.8 0.0 4.7e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Pox_L5 PF04872.8 AJZ75655.1 - 0.057 13.0 0.1 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus L5 protein family Ribosomal_S9 PF00380.14 AJZ75656.1 - 7.4e-35 119.8 1.2 8.6e-35 119.6 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 NTP_transferase PF00483.18 AJZ75657.1 - 4.9e-20 71.8 0.0 5.8e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AJZ75657.1 - 8.6e-12 45.4 0.0 1.1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 AJZ75657.1 - 3.8e-05 23.3 0.0 5.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 AJZ75657.1 - 0.00076 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase SurA_N_2 PF13623.1 AJZ75657.1 - 0.016 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 SurA N-terminal domain Antimicrobial_7 PF08102.6 AJZ75657.1 - 0.02 14.9 0.2 0.22 11.5 0.1 2.5 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Aconitase_C PF00694.14 AJZ75658.1 - 6e-40 136.3 0.0 8e-40 135.9 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 AJZ75658.1 - 0.0037 16.7 0.0 0.066 12.6 0.0 2.0 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase PF00330.15 AJZ75659.1 - 2.1e-162 540.8 0.0 2.3e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.8 AJZ75659.1 - 0.0069 14.9 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Aconitase_C PF00694.14 AJZ75660.1 - 4e-21 75.5 0.0 6.6e-20 71.5 0.0 2.1 1 1 1 2 2 2 2 Aconitase C-terminal domain Aconitase_2_N PF06434.8 AJZ75660.1 - 0.00049 19.5 0.2 0.0018 17.6 0.1 1.9 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus F420_ligase PF01996.11 AJZ75661.1 - 5.1e-54 182.7 1.3 3.6e-53 179.9 0.1 1.9 1 1 1 2 2 2 2 F420-0:Gamma-glutamyl ligase DUF507 PF04368.8 AJZ75662.1 - 0.048 13.3 0.3 0.092 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Nsp1_C PF05064.8 AJZ75664.1 - 0.13 11.9 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region TPP_enzyme_C PF02775.16 AJZ75665.1 - 5.5e-31 107.1 0.3 1e-30 106.3 0.2 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.3 AJZ75665.1 - 1.4e-08 34.5 0.6 7.8e-06 25.7 0.4 3.1 1 1 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal POR_N PF01855.14 AJZ75666.1 - 2.4e-56 190.8 0.0 3.5e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.13 AJZ75666.1 - 4.4e-34 117.8 0.1 9.5e-34 116.7 0.1 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 AJZ75666.1 - 1.2e-06 28.4 0.0 2.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_N PF02776.13 AJZ75666.1 - 0.0063 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2-Hacid_dh_C PF02826.14 AJZ75667.1 - 1.4e-64 216.5 0.1 2.1e-64 215.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AJZ75667.1 - 7.8e-32 109.5 0.0 8.8e-32 109.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AJZ75667.1 - 1.5e-07 31.4 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 AJZ75667.1 - 4.7e-06 26.0 0.0 9.3e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 AJZ75667.1 - 0.0019 18.5 0.0 0.0048 17.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 AJZ75667.1 - 0.023 14.5 0.1 0.27 11.0 0.0 2.3 2 1 1 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_5 PF07994.7 AJZ75668.1 - 1.5e-42 146.0 0.0 4.2e-42 144.6 0.0 1.6 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 AJZ75668.1 - 3.6e-29 100.8 0.0 6.9e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase AMP-binding_C_2 PF14535.1 AJZ75668.1 - 0.023 14.7 0.2 0.8 9.7 0.0 2.5 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain TruB_N PF01509.13 AJZ75670.1 - 2.7e-24 86.0 2.0 2.4e-14 53.7 0.0 3.5 2 1 1 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 AJZ75670.1 - 7e-17 60.9 0.1 1.4e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 PUA domain DKCLD PF08068.7 AJZ75670.1 - 4.2e-11 42.5 0.0 9.2e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 DKCLD (NUC011) domain Cytidylate_kin2 PF13189.1 AJZ75671.1 - 5e-12 46.0 0.0 6.3e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.1 AJZ75671.1 - 8.8e-12 45.4 0.0 1.4e-11 44.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AJZ75671.1 - 5.9e-09 36.7 0.1 9.9e-09 36.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 AJZ75671.1 - 0.00021 21.2 2.5 0.00057 19.7 0.1 2.2 2 1 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.1 AJZ75671.1 - 0.00042 20.3 0.1 0.00081 19.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 AJZ75671.1 - 0.00058 19.7 0.3 0.002 18.0 0.2 1.8 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 AJZ75671.1 - 0.00097 19.0 0.1 0.0024 17.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 AJZ75671.1 - 0.006 16.7 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 AJZ75671.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Prenylcys_lyase PF07156.9 AJZ75671.1 - 0.013 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Prenylcysteine lyase KTI12 PF08433.5 AJZ75671.1 - 0.029 13.5 0.0 0.049 12.8 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_26 PF13500.1 AJZ75671.1 - 0.039 13.5 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Nif11 PF07862.6 AJZ75671.1 - 0.05 13.5 1.3 1.3 8.9 0.0 3.0 3 0 0 3 3 3 0 Nitrogen fixation protein of unknown function NTPase_1 PF03266.10 AJZ75671.1 - 0.086 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 AJZ75671.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 AJZ75671.1 - 0.12 11.4 0.1 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF106 PF01956.11 AJZ75672.1 - 2.4e-13 49.9 10.7 1.2e-12 47.6 7.4 1.8 1 1 0 1 1 1 1 Integral membrane protein DUF106 AAA_18 PF13238.1 AJZ75673.1 - 4.2e-10 40.0 0.1 5.7e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 AJZ75673.1 - 8e-08 31.9 0.1 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 AJZ75673.1 - 1.5e-06 29.0 0.0 2.7e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AJZ75673.1 - 1.8e-05 24.4 0.5 2.8e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AJZ75673.1 - 3.7e-05 23.7 0.0 7.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 AJZ75673.1 - 0.00011 21.9 0.1 0.00016 21.4 0.1 1.5 1 1 0 1 1 1 1 NACHT domain MobB PF03205.9 AJZ75673.1 - 0.00012 21.7 2.1 0.00025 20.7 1.4 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 AJZ75673.1 - 0.0002 21.1 0.3 0.00036 20.3 0.1 1.4 2 0 0 2 2 1 1 Archaeal ATPase NTPase_1 PF03266.10 AJZ75673.1 - 0.0004 20.1 1.5 0.0004 20.1 1.1 2.1 2 1 0 2 2 2 1 NTPase KTI12 PF08433.5 AJZ75673.1 - 0.00051 19.3 0.4 0.0011 18.1 0.1 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 ATP_bind_1 PF03029.12 AJZ75673.1 - 0.00053 19.6 1.4 0.00091 18.8 0.2 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 AJZ75673.1 - 0.00064 19.7 0.2 0.003 17.5 0.1 1.8 1 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 AJZ75673.1 - 0.00069 19.9 0.5 0.00078 19.7 0.4 1.4 1 1 0 1 1 1 1 ABC transporter cobW PF02492.14 AJZ75673.1 - 0.00088 18.7 0.1 0.0013 18.1 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 AJZ75673.1 - 0.001 18.9 0.1 0.0046 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 AJZ75673.1 - 0.0011 18.8 0.3 0.0014 18.5 0.2 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 AJZ75673.1 - 0.0015 18.2 0.3 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain Miro PF08477.8 AJZ75673.1 - 0.0034 17.8 0.7 0.0063 16.9 0.3 1.7 2 0 0 2 2 1 1 Miro-like protein Viral_helicase1 PF01443.13 AJZ75673.1 - 0.0047 16.4 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 AJZ75673.1 - 0.0051 15.7 0.1 0.0068 15.3 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain UPF0079 PF02367.12 AJZ75673.1 - 0.0055 16.3 0.0 0.009 15.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 AJZ75673.1 - 0.0082 16.0 0.1 0.016 15.0 0.0 1.5 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.15 AJZ75673.1 - 0.0085 15.7 0.3 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_22 PF13401.1 AJZ75673.1 - 0.0089 16.1 1.3 0.03 14.4 0.9 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 AJZ75673.1 - 0.011 15.1 0.7 0.054 12.8 0.3 2.2 2 1 0 2 2 2 0 Thymidylate kinase SRPRB PF09439.5 AJZ75673.1 - 0.012 14.8 0.1 0.017 14.3 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 AJZ75673.1 - 0.014 15.6 2.0 0.036 14.2 1.4 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 AJZ75673.1 - 0.014 14.5 0.8 0.031 13.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 AJZ75673.1 - 0.019 14.4 0.1 0.035 13.5 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 AJZ75673.1 - 0.022 13.5 0.1 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein PRK PF00485.13 AJZ75673.1 - 0.023 14.2 0.1 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.4 AJZ75673.1 - 0.023 13.6 0.2 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_15 PF13175.1 AJZ75673.1 - 0.026 13.5 0.3 0.033 13.2 0.2 1.2 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.9 AJZ75673.1 - 0.028 13.3 0.2 0.043 12.7 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase Zeta_toxin PF06414.7 AJZ75673.1 - 0.046 12.8 0.4 0.084 11.9 0.3 1.5 1 1 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 AJZ75673.1 - 0.056 12.5 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arf PF00025.16 AJZ75673.1 - 0.065 12.4 1.4 0.077 12.2 0.2 1.8 2 1 0 2 2 1 0 ADP-ribosylation factor family AAA_29 PF13555.1 AJZ75673.1 - 0.07 12.6 0.2 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 AJZ75673.1 - 0.07 12.8 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 AJZ75673.1 - 0.078 12.3 0.3 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain LpxK PF02606.9 AJZ75673.1 - 0.09 11.7 0.3 0.15 11.0 0.2 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase DUF463 PF04317.7 AJZ75673.1 - 0.11 10.9 0.1 0.15 10.5 0.1 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 CbiA PF01656.18 AJZ75673.1 - 0.12 11.7 3.0 0.52 9.6 2.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.2 AJZ75673.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 T2SE PF00437.15 AJZ75673.1 - 0.14 10.9 2.5 0.28 10.0 1.6 1.7 1 1 1 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.12 AJZ75673.1 - 0.15 11.8 1.8 0.35 10.6 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_24 PF13479.1 AJZ75673.1 - 0.28 10.7 1.3 0.43 10.1 0.9 1.5 1 1 0 1 1 1 0 AAA domain SecY PF00344.15 AJZ75674.1 - 7.3e-84 281.6 19.8 9.1e-84 281.3 13.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 AJZ75674.1 - 8.3e-11 41.2 1.0 2.8e-10 39.5 0.7 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Phage_holin_5 PF06946.6 AJZ75674.1 - 0.069 13.3 0.1 0.069 13.3 0.1 2.9 3 0 0 3 3 3 0 Phage holin Ribosomal_L18e PF00828.14 AJZ75675.1 - 8.7e-20 71.4 0.4 1.1e-19 71.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L30 PF00327.15 AJZ75676.1 - 2.3e-13 49.5 0.1 4.4e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5 PF00333.15 AJZ75677.1 - 2e-19 69.0 0.3 3.4e-19 68.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 AJZ75677.1 - 2.2e-15 55.6 0.8 3.2e-15 55.1 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_L18p PF00861.17 AJZ75678.1 - 1.8e-22 79.7 0.5 2.4e-22 79.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L18p/L5e family SRP54 PF00448.17 AJZ75679.1 - 3.1e-71 238.8 1.4 4.6e-71 238.3 1.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 AJZ75679.1 - 3e-09 36.8 6.2 7.7e-09 35.5 4.3 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.1 AJZ75679.1 - 7e-07 29.0 0.1 1.2e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 AJZ75679.1 - 1.5e-05 24.5 1.3 5.2e-05 22.7 0.9 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 AJZ75679.1 - 4.4e-05 23.6 0.5 0.00017 21.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 AJZ75679.1 - 5.8e-05 22.8 0.9 0.0003 20.5 0.1 2.4 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 AJZ75679.1 - 6.1e-05 22.5 0.6 0.00012 21.5 0.4 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 AJZ75679.1 - 0.00025 21.0 0.0 0.00044 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.9 AJZ75679.1 - 0.00039 19.4 0.2 0.0006 18.8 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase Zeta_toxin PF06414.7 AJZ75679.1 - 0.00044 19.3 0.1 0.00073 18.6 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin DUF2075 PF09848.4 AJZ75679.1 - 0.00079 18.4 0.1 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.15 AJZ75679.1 - 0.00089 18.9 0.2 0.0083 15.7 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.1 AJZ75679.1 - 0.0016 18.3 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AJZ75679.1 - 0.0021 18.2 0.1 0.0054 16.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 AJZ75679.1 - 0.0039 17.4 0.0 0.0072 16.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Thymidylate_kin PF02223.12 AJZ75679.1 - 0.0052 16.1 0.0 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_19 PF13245.1 AJZ75679.1 - 0.0053 16.4 0.1 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_15 PF13175.1 AJZ75679.1 - 0.017 14.2 2.8 0.021 13.8 0.4 2.0 1 1 1 2 2 2 0 AAA ATPase domain ResIII PF04851.10 AJZ75679.1 - 0.026 14.3 0.5 0.026 14.3 0.4 2.1 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 AJZ75679.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 AJZ75679.1 - 0.032 13.4 0.0 0.082 12.0 0.0 1.8 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ArgK PF03308.11 AJZ75679.1 - 0.035 12.9 0.1 0.1 11.3 0.1 1.7 1 1 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 AJZ75679.1 - 0.037 13.4 0.5 0.44 9.9 0.5 2.5 2 1 0 2 2 2 0 AAA domain TPP_enzyme_M PF00205.17 AJZ75679.1 - 0.039 13.7 0.2 0.76 9.5 0.1 2.6 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain 6PF2K PF01591.13 AJZ75679.1 - 0.04 12.9 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_5 PF07728.9 AJZ75679.1 - 0.042 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 AJZ75679.1 - 0.047 13.3 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.22 AJZ75679.1 - 0.056 12.8 0.1 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 AJZ75679.1 - 0.057 14.2 2.6 0.068 13.9 0.0 2.5 3 1 0 3 3 2 0 AAA domain AAA_24 PF13479.1 AJZ75679.1 - 0.059 12.9 1.4 0.16 11.5 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AJZ75679.1 - 0.077 12.8 0.1 0.18 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain SPOUT_MTase PF02590.12 AJZ75679.1 - 0.087 12.5 0.0 0.23 11.1 0.0 1.7 1 1 0 1 1 1 0 Predicted SPOUT methyltransferase NTPase_1 PF03266.10 AJZ75679.1 - 0.1 12.2 0.8 2.1 8.0 0.5 2.4 1 1 0 1 1 1 0 NTPase G-alpha PF00503.15 AJZ75679.1 - 0.29 9.7 0.0 0.29 9.7 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Cupin_2 PF07883.6 AJZ75680.1 - 6e-08 32.0 0.0 8.5e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 AJZ75680.1 - 1.2e-06 28.3 0.0 1.5e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 AJZ75680.1 - 0.028 14.0 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Sod_Fe_C PF02777.13 AJZ75681.1 - 1e-42 144.2 0.8 2e-42 143.2 0.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AJZ75681.1 - 3.5e-27 94.4 0.9 3.5e-27 94.4 0.6 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Peptidase_S8 PF00082.17 AJZ75682.1 - 1.8e-62 211.0 0.2 2.5e-62 210.5 0.2 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 AJZ75682.1 - 6.7e-11 41.7 0.1 3e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 PA domain DUF2388 PF09498.5 AJZ75682.1 - 0.092 12.3 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) Ribosomal_L32e PF01655.13 AJZ75683.1 - 1.4e-38 131.2 1.5 1.7e-38 131.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 ALMS_motif PF15309.1 AJZ75683.1 - 0.077 12.8 0.2 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 ALMS motif Troponin PF00992.15 AJZ75683.1 - 0.12 12.4 0.5 0.24 11.4 0.2 1.6 2 0 0 2 2 2 0 Troponin NDUF_B12 PF08122.7 AJZ75683.1 - 0.21 11.3 2.9 17 5.2 2.0 2.5 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family Ribosomal_L19e PF01280.15 AJZ75684.1 - 5.2e-42 143.0 10.6 6.2e-42 142.8 7.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e DNA_binding_1 PF01035.15 AJZ75685.1 - 3.4e-28 97.2 0.0 3.8e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain tRNA_deacylase PF04414.7 AJZ75686.1 - 5.8e-58 195.5 0.1 6.9e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase MbeD_MobD PF04899.7 AJZ75686.1 - 0.025 14.4 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 MbeD/MobD like Frag1 PF10277.4 AJZ75687.1 - 0.059 12.8 0.0 0.066 12.6 0.0 1.0 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Ribosomal_L11_N PF03946.9 AJZ75688.1 - 2.6e-23 81.2 1.7 4e-23 80.6 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AJZ75688.1 - 1.4e-19 69.9 1.8 2.4e-19 69.2 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SBP_bac_5 PF00496.17 AJZ75688.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Ribosomal_L1 PF00687.16 AJZ75689.1 - 4.9e-45 153.5 0.3 5.9e-45 153.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L10 PF00466.15 AJZ75690.1 - 1.6e-16 60.0 0.6 3.3e-16 59.0 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 AJZ75691.1 - 5.3e-14 52.3 19.1 6.2e-14 52.1 13.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein NTS_2 PF15448.1 AJZ75691.1 - 0.089 13.1 0.1 7.2 6.9 0.0 2.2 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein tRNA-synt_2c PF01411.14 AJZ75693.1 - 3.9e-82 276.3 0.1 9.3e-82 275.0 0.1 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 AJZ75693.1 - 7.3e-16 57.7 0.9 1.9e-15 56.4 0.6 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 AJZ75693.1 - 7.4e-06 25.5 2.3 1.7e-05 24.4 1.6 1.6 1 0 0 1 1 1 1 DHHA1 domain Sigma70_ner PF04546.8 AJZ75693.1 - 0.04 13.5 0.6 0.096 12.2 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region tRNA-synt_1 PF00133.17 AJZ75694.1 - 2.3e-55 187.7 1.2 1.6e-53 181.6 0.8 2.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AJZ75694.1 - 1.8e-26 92.7 0.3 1.5e-12 46.8 0.0 3.4 2 1 1 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AJZ75694.1 - 1.9e-22 79.6 0.1 4.2e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 AJZ75694.1 - 3.8e-12 45.9 0.0 1.3e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 AJZ75694.1 - 2.2e-09 36.8 0.3 1.2e-07 31.2 0.2 2.7 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 AJZ75694.1 - 0.036 12.8 0.0 0.19 10.5 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (R) SAM_1 PF00536.25 AJZ75694.1 - 0.055 13.6 0.0 0.19 11.9 0.0 2.0 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Trp_halogenase PF04820.9 AJZ75695.1 - 0.00011 21.0 0.0 0.00031 19.4 0.0 1.6 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_2 PF03446.10 AJZ75695.1 - 0.0094 15.8 0.1 0.027 14.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Na_H_Exchanger PF00999.16 AJZ75696.1 - 1.2e-62 211.6 59.9 1.5e-62 211.3 41.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CxxCxxCC PF03692.10 AJZ75697.1 - 1.8e-09 37.9 0.1 3.9e-09 36.8 0.1 1.6 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Ribosomal_S7 PF00177.16 AJZ75699.1 - 1.7e-36 125.0 2.1 2.7e-36 124.3 1.4 1.3 1 1 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.20 AJZ75700.1 - 3.7e-39 132.9 0.5 4.6e-39 132.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 KH_2 PF07650.12 AJZ75701.1 - 8.4e-21 73.3 4.1 1.3e-14 53.5 0.2 2.1 1 1 1 2 2 2 2 KH domain KH_4 PF13083.1 AJZ75701.1 - 8.4e-10 38.1 1.1 0.00071 19.1 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 AJZ75701.1 - 1.9e-09 37.2 3.6 4e-09 36.1 0.2 2.1 2 0 0 2 2 2 1 NusA-like KH domain KH_1 PF00013.24 AJZ75701.1 - 6.2e-08 32.1 1.1 0.00025 20.6 0.0 2.6 3 0 0 3 3 3 2 KH domain DUF310 PF03750.8 AJZ75701.1 - 0.052 13.7 0.1 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF310) Ribosomal_L7Ae PF01248.21 AJZ75702.1 - 2.9e-11 42.7 2.0 3.3e-11 42.5 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Kazal_1 PF00050.16 AJZ75703.1 - 3.9e-07 29.9 1.1 3.9e-07 29.9 0.7 1.7 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 AJZ75703.1 - 1.9e-06 27.7 0.5 4.2e-06 26.5 0.4 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain BiPBP_C PF06832.7 AJZ75703.1 - 0.027 14.3 0.1 11 5.9 0.0 2.5 2 1 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family PD40 PF07676.7 AJZ75703.1 - 0.037 13.7 0.7 9.9 5.9 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat A2M_N PF01835.14 AJZ75704.1 - 0.0017 18.5 0.3 0.28 11.4 0.0 3.3 3 1 1 4 4 4 1 MG2 domain RNA_pol_Rpb1_5 PF04998.12 AJZ75705.1 - 3.3e-84 282.4 3.9 8.7e-84 281.0 2.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 AJZ75705.1 - 4.9e-84 282.4 0.3 2.1e-82 277.1 0.0 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 AJZ75705.1 - 8.3e-69 230.7 0.0 1.6e-68 229.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 AJZ75705.1 - 1.6e-32 112.4 0.0 3.6e-32 111.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AJZ75705.1 - 1.6e-26 92.1 0.3 4.5e-26 90.7 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Spore_III_AF PF09581.5 AJZ75705.1 - 0.13 12.0 3.3 0.25 11.1 0.5 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) zf-ribbon_3 PF13248.1 AJZ75705.1 - 0.27 10.5 2.5 0.27 10.5 0.1 2.2 2 1 0 2 2 2 0 zinc-ribbon domain RNA_pol_Rpb2_6 PF00562.23 AJZ75706.1 - 4e-121 404.4 0.0 8.5e-121 403.3 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AJZ75706.1 - 1.8e-55 187.0 0.0 3.7e-55 185.9 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 AJZ75706.1 - 8.2e-31 106.1 0.1 1.8e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 AJZ75706.1 - 5.2e-28 96.6 0.0 1.2e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 AJZ75706.1 - 3.4e-23 82.0 0.0 7e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 AJZ75706.1 - 6.4e-13 48.3 0.1 2.4e-12 46.4 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 AJZ75706.1 - 7e-12 45.1 0.2 1.5e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 OrfB_Zn_ribbon PF07282.6 AJZ75706.1 - 0.22 11.1 1.2 0.92 9.2 0.9 2.0 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_L37e PF01907.14 AJZ75706.1 - 0.24 11.2 0.9 0.57 10.0 0.6 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e Zn_Tnp_IS1595 PF12760.2 AJZ75706.1 - 0.32 10.8 0.7 0.7 9.7 0.5 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Aminotran_5 PF00266.14 AJZ75707.1 - 8.7e-88 294.5 0.6 1e-87 294.3 0.4 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AJZ75707.1 - 1.5e-10 40.7 0.1 5.5e-10 38.8 0.0 1.6 1 1 0 2 2 2 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 AJZ75707.1 - 0.00031 19.9 0.1 0.001 18.2 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 AJZ75707.1 - 0.0057 15.1 0.0 0.0099 14.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain MR_MLE_C PF13378.1 AJZ75707.1 - 0.081 12.9 0.1 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Enolase C-terminal domain-like tRNA_Me_trans PF03054.11 AJZ75708.1 - 5.6e-09 35.0 0.2 4.4e-07 28.7 0.1 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.8 AJZ75708.1 - 5.8e-09 35.5 0.0 3.6e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 AJZ75708.1 - 7e-09 34.9 0.0 1.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 AJZ75708.1 - 1.2e-08 34.7 0.1 3.6e-08 33.2 0.1 1.7 1 1 1 2 2 2 1 Asparagine synthase ATP_bind_3 PF01171.15 AJZ75708.1 - 1.2e-07 31.4 0.1 8.4e-07 28.6 0.1 2.1 2 0 0 2 2 2 1 PP-loop family DUF4434 PF14488.1 AJZ75708.1 - 0.045 13.4 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) ThiI PF02568.9 AJZ75708.1 - 0.1 12.0 0.1 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Ldh_1_N PF00056.18 AJZ75709.1 - 1.5e-36 125.3 1.0 2.8e-36 124.4 0.7 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AJZ75709.1 - 5.3e-26 91.3 0.0 7.6e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Transaldolase PF00923.14 AJZ75709.1 - 0.12 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Transaldolase AIRC PF00731.15 AJZ75710.1 - 1.5e-23 82.7 3.4 2.2e-23 82.1 2.4 1.3 1 0 0 1 1 1 1 AIR carboxylase Staphylokinase PF02821.11 AJZ75710.1 - 0.056 13.2 0.2 0.095 12.4 0.1 1.3 1 0 0 1 1 1 0 Staphylokinase/Streptokinase family VIT1 PF01988.14 AJZ75711.1 - 6.8e-55 185.8 2.2 8.3e-55 185.5 1.6 1.0 1 0 0 1 1 1 1 VIT family Carbpep_Y_N PF05388.6 AJZ75711.1 - 0.047 13.8 0.1 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide DUF1049 PF06305.6 AJZ75711.1 - 0.79 9.2 8.5 12 5.4 1.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) Radical_SAM PF04055.16 AJZ75712.1 - 2.5e-12 47.2 0.0 4.4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.14 AJZ75712.1 - 0.029 14.2 0.0 0.086 12.7 0.0 1.8 2 0 0 2 2 2 0 B12 binding domain DUF2136 PF09907.4 AJZ75713.1 - 0.031 14.3 0.7 0.068 13.2 0.1 1.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2136) Zip PF02535.17 AJZ75714.1 - 4e-07 29.3 16.8 4e-07 29.3 11.6 2.5 1 1 1 2 2 2 1 ZIP Zinc transporter DUF4342 PF14242.1 AJZ75714.1 - 0.039 13.7 0.1 0.039 13.7 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4342) DUF2374 PF09574.5 AJZ75715.1 - 0.019 14.6 1.5 0.082 12.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) HCV_NS4a PF01006.15 AJZ75715.1 - 0.12 11.9 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a TrmB PF01978.14 AJZ75716.1 - 0.0038 16.8 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DNA_processg_A PF02481.10 AJZ75716.1 - 0.011 14.6 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A DUF4423 PF14394.1 AJZ75716.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) Cullin_Nedd8 PF10557.4 AJZ75716.1 - 0.042 13.6 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Cullin protein neddylation domain VWA_2 PF13519.1 AJZ75717.1 - 7.1e-14 52.2 0.1 7.1e-13 49.0 0.0 2.7 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 AJZ75717.1 - 0.003 17.2 0.1 0.0087 15.7 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain MyTH4 PF00784.12 AJZ75717.1 - 0.013 15.4 1.6 0.024 14.5 0.3 2.2 3 0 0 3 3 3 0 MyTH4 domain AAA_5 PF07728.9 AJZ75718.1 - 2.7e-08 33.6 0.0 0.00022 20.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 AJZ75718.1 - 1.2e-07 30.7 0.0 6e-07 28.4 0.0 1.9 1 1 0 1 1 1 1 PrkA AAA domain AAA_3 PF07726.6 AJZ75718.1 - 7.2e-06 25.6 0.0 0.00014 21.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AJZ75718.1 - 8.5e-06 25.3 0.0 4.8e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.18 AJZ75718.1 - 0.004 16.0 0.0 0.022 13.5 0.0 2.0 2 0 0 2 2 2 1 MCM2/3/5 family Mg_chelatase PF01078.16 AJZ75718.1 - 0.011 14.9 0.0 1 8.4 0.0 2.6 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI FUSC-like PF12805.2 AJZ75718.1 - 0.026 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Ribosomal_S13 PF00416.17 AJZ75719.1 - 6.5e-30 103.7 0.0 7.9e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.1 AJZ75719.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif S4 PF01479.20 AJZ75720.1 - 8.4e-10 37.9 0.0 8.4e-10 37.9 0.0 2.1 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.14 AJZ75720.1 - 2.1e-06 28.0 0.5 3.1e-06 27.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain SIS PF01380.17 AJZ75721.1 - 3.3e-46 156.1 1.7 1.3e-25 89.5 0.7 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 AJZ75721.1 - 4e-24 85.0 0.1 7.2e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 AJZ75721.1 - 1.6e-21 76.4 0.3 2e-17 62.9 0.1 2.6 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 AJZ75721.1 - 1.8e-18 66.4 0.1 5.3e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 AJZ75721.1 - 2.5e-06 26.3 0.1 4e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 AJZ75721.1 - 3.6e-06 26.7 4.4 0.00077 19.1 0.4 3.4 2 1 1 3 3 3 2 SIS domain VWA_2 PF13519.1 AJZ75721.1 - 0.0072 16.4 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain ParA PF10609.4 AJZ75721.1 - 0.053 13.4 0.8 2.1 8.3 0.1 3.0 3 1 1 4 4 4 0 ParA/MinD ATPase like DBI_PRT PF02277.12 AJZ75722.1 - 1.1e-26 93.6 1.6 1.8e-26 93.0 1.1 1.2 1 0 0 1 1 1 1 Phosphoribosyltransferase Lactamase_B PF00753.22 AJZ75723.1 - 6e-27 94.5 0.2 8.2e-27 94.1 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AJZ75723.1 - 8.6e-08 31.9 0.1 1e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CBS PF00571.23 AJZ75723.1 - 0.012 15.3 0.1 0.053 13.3 0.0 2.0 2 0 0 2 2 2 0 CBS domain Lactamase_B_3 PF13483.1 AJZ75723.1 - 0.012 15.2 0.9 0.025 14.3 0.6 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain YjeF_N PF03853.10 AJZ75724.1 - 7.2e-49 165.6 0.1 8.4e-49 165.4 0.1 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus Translin PF01997.11 AJZ75725.1 - 9.8e-26 90.5 2.2 1.5e-25 90.0 1.5 1.3 1 0 0 1 1 1 1 Translin family tRNA_anti-like PF12869.2 AJZ75725.1 - 0.064 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 tRNA_anti-like Snf7 PF03357.16 AJZ75725.1 - 0.11 11.8 7.1 0.28 10.5 4.9 1.6 1 0 0 1 1 1 0 Snf7 Enolase_C PF00113.17 AJZ75726.1 - 1.9e-57 194.4 0.0 3e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 AJZ75726.1 - 1.9e-28 98.9 0.3 3.4e-28 98.2 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain CW_binding_2 PF04122.7 AJZ75726.1 - 0.0012 19.0 1.6 0.002 18.2 0.2 2.1 2 0 0 2 2 2 1 Putative cell wall binding repeat 2 DBP10CT PF08147.7 AJZ75726.1 - 0.02 14.6 2.3 0.028 14.2 0.1 2.1 2 0 0 2 2 2 0 DBP10CT (NUC160) domain Pinin_SDK_N PF04697.8 AJZ75726.1 - 0.1 12.6 0.1 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 pinin/SDK conserved region Ribosomal_S2 PF00318.15 AJZ75727.1 - 5e-36 123.9 0.2 1.9e-17 63.2 0.3 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 Memo PF01875.12 AJZ75728.1 - 2.5e-78 262.7 0.2 2.8e-78 262.5 0.2 1.0 1 0 0 1 1 1 1 Memo-like protein GHMP_kinases_N PF00288.21 AJZ75729.1 - 5.3e-17 61.6 1.5 5.3e-17 61.6 1.1 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AJZ75729.1 - 1.3e-11 44.5 0.0 2.8e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Prenylcys_lyase PF07156.9 AJZ75729.1 - 0.00067 18.6 0.1 0.0012 17.8 0.1 1.4 1 0 0 1 1 1 1 Prenylcysteine lyase AA_kinase PF00696.23 AJZ75730.1 - 1.1e-25 90.5 0.0 1.3e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family Mo25 PF08569.6 AJZ75730.1 - 0.088 11.8 0.8 0.16 10.9 0.1 1.7 2 0 0 2 2 2 0 Mo25-like NUDIX PF00293.23 AJZ75731.1 - 1.7e-13 50.3 0.0 2.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain polyprenyl_synt PF00348.12 AJZ75732.1 - 1.1e-67 227.6 0.0 1.3e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase tRNA-synt_1c PF00749.16 AJZ75733.1 - 7.4e-77 258.0 0.0 9.5e-77 257.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AJZ75733.1 - 1.3e-24 86.8 0.0 3e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 AJZ75733.1 - 0.064 12.3 2.0 0.85 8.6 1.4 2.2 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain FAA_hydrolase PF01557.13 AJZ75734.1 - 1.3e-65 220.9 0.0 1.5e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.4 AJZ75734.1 - 0.0041 17.4 0.0 0.026 14.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2437) Rieske PF00355.21 AJZ75735.1 - 5.8e-17 61.0 0.0 6.1e-17 60.9 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AJZ75735.1 - 3.1e-07 30.0 0.0 3.6e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0147 PF03685.8 AJZ75736.1 - 1.5e-30 104.8 0.8 1.7e-30 104.7 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) UPF0253 PF06786.7 AJZ75736.1 - 0.0014 18.6 0.1 1.2 9.3 0.0 2.2 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0253) DUF1539 PF07560.6 AJZ75736.1 - 0.027 14.3 0.3 0.042 13.7 0.2 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) Adaptin_N PF01602.15 AJZ75736.1 - 0.076 11.3 0.1 0.085 11.1 0.1 1.0 1 0 0 1 1 1 0 Adaptin N terminal region DUF4211 PF13926.1 AJZ75736.1 - 0.081 12.3 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) DUF3783 PF12646.2 AJZ75736.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) DOT1 PF08123.8 AJZ75737.1 - 1.1e-06 28.0 0.1 0.001 18.3 0.0 2.1 1 1 1 2 2 2 2 Histone methylation protein DOT1 Methyltransf_11 PF08241.7 AJZ75737.1 - 3.7e-05 24.1 0.0 8.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJZ75737.1 - 9.2e-05 22.9 0.0 0.00018 22.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJZ75737.1 - 0.00013 21.6 0.4 0.0002 20.9 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJZ75737.1 - 0.0013 19.0 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AJZ75737.1 - 0.0073 15.4 0.0 0.0095 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 AJZ75737.1 - 0.012 15.6 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 AJZ75737.1 - 0.019 14.0 0.0 0.039 13.0 0.0 1.4 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 AJZ75737.1 - 0.076 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GspL_C PF12693.2 AJZ75738.1 - 0.012 15.3 0.0 0.063 13.0 0.0 1.9 2 0 0 2 2 2 0 GspL periplasmic domain CorA PF01544.13 AJZ75739.1 - 1.6e-59 201.3 4.5 2e-59 201.0 3.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TraF_2 PF13729.1 AJZ75739.1 - 0.012 14.4 1.2 0.015 14.0 0.1 1.7 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein Radical_SAM PF04055.16 AJZ75740.1 - 8.2e-19 68.3 0.0 1.3e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 AJZ75740.1 - 1.9e-18 66.3 0.0 5e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Fer4_14 PF13394.1 AJZ75740.1 - 0.0035 17.3 0.0 0.011 15.7 0.0 1.9 1 1 0 1 1 1 1 4Fe-4S single cluster domain Ham1p_like PF01725.11 AJZ75741.1 - 5.3e-43 146.5 0.0 6.1e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RIO1 PF01163.17 AJZ75742.1 - 1.2e-09 37.8 0.0 1.5e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 AJZ75742.1 - 7.9e-07 28.4 0.2 1.1e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 AJZ75742.1 - 5.6e-05 22.2 0.0 0.00025 20.2 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AJZ75742.1 - 0.00027 20.7 0.0 0.00039 20.2 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 AJZ75742.1 - 0.0012 18.1 0.1 0.0014 17.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.12 AJZ75742.1 - 0.0017 17.4 0.1 0.0022 17.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase GRAM PF02893.15 AJZ75743.1 - 0.0095 15.4 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 GRAM domain bPH_3 PF14470.1 AJZ75743.1 - 0.031 14.5 0.2 0.053 13.7 0.2 1.5 1 1 0 1 1 1 0 Bacterial PH domain Peptidase_M22 PF00814.20 AJZ75744.1 - 2.9e-72 243.3 0.0 3.4e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DUF512 PF04459.7 AJZ75744.1 - 0.023 13.7 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) MMR_HSR1_C PF08438.5 AJZ75745.1 - 1.8e-31 108.5 0.4 3.2e-31 107.7 0.3 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 AJZ75745.1 - 1.3e-17 63.7 0.1 4.3e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 AJZ75745.1 - 7.9e-13 48.0 0.1 2e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 AJZ75745.1 - 1.7e-07 30.6 1.9 4.7e-07 29.2 0.2 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B YchF-GTPase_C PF06071.8 AJZ75745.1 - 0.0026 17.4 0.3 0.022 14.5 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF933) AAA_18 PF13238.1 AJZ75746.1 - 3.9e-15 56.3 0.3 5.4e-15 55.8 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AJZ75746.1 - 1.8e-13 51.3 0.1 3.1e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 AJZ75746.1 - 2.5e-07 30.7 0.1 0.001 19.0 0.0 2.2 1 1 1 2 2 2 2 Cytidylate kinase-like family KTI12 PF08433.5 AJZ75746.1 - 0.00015 21.0 0.7 0.00031 20.0 0.5 1.7 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA PF00004.24 AJZ75746.1 - 0.00027 21.1 0.6 0.00067 19.8 0.4 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AJZ75746.1 - 0.0005 19.9 0.0 0.0017 18.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain CoaE PF01121.15 AJZ75746.1 - 0.00056 19.3 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 Dephospho-CoA kinase SKI PF01202.17 AJZ75746.1 - 0.0008 19.3 0.0 0.002 18.0 0.0 1.7 1 1 0 1 1 1 1 Shikimate kinase NTPase_1 PF03266.10 AJZ75746.1 - 0.0018 17.9 0.8 0.0053 16.4 0.2 2.0 1 1 0 1 1 1 1 NTPase APS_kinase PF01583.15 AJZ75746.1 - 0.004 16.8 0.0 0.0096 15.5 0.0 1.7 1 1 0 1 1 1 1 Adenylylsulphate kinase MCM_N PF14551.1 AJZ75746.1 - 0.033 14.6 0.1 0.091 13.2 0.1 1.8 1 1 0 1 1 1 0 MCM N-terminal domain AAA_5 PF07728.9 AJZ75746.1 - 0.052 13.2 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 AJZ75746.1 - 0.052 13.5 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain CUT PF02376.10 AJZ75746.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 CUT domain AAA_22 PF13401.1 AJZ75746.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AJZ75746.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TGT PF01702.13 AJZ75747.1 - 2.1e-45 154.8 0.0 3e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Fer4 PF00037.22 AJZ75748.1 - 5.1e-11 41.6 10.8 6.6e-06 25.5 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AJZ75748.1 - 1e-09 38.6 3.5 1.4e-09 38.1 2.4 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 AJZ75748.1 - 3.3e-09 36.2 10.0 0.00035 20.3 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 AJZ75748.1 - 9.4e-09 34.6 7.7 0.00016 21.3 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 AJZ75748.1 - 9.6e-09 34.9 2.9 1.7e-08 34.0 2.1 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AJZ75748.1 - 4.5e-07 29.6 3.4 7.2e-07 28.9 2.4 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_13 PF13370.1 AJZ75748.1 - 1.5e-06 28.4 5.1 0.0036 17.6 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 AJZ75748.1 - 1.8e-06 28.3 8.6 0.00053 20.5 6.0 2.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_4 PF12800.2 AJZ75748.1 - 1.4e-05 25.0 9.3 0.033 14.5 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 AJZ75748.1 - 2.5e-05 24.4 6.0 0.0001 22.4 4.3 1.8 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 AJZ75748.1 - 6.8e-05 22.8 4.1 0.00019 21.4 2.8 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 AJZ75748.1 - 0.00011 22.8 1.3 0.36 11.6 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 AJZ75748.1 - 0.00032 21.0 11.3 0.068 13.7 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 AJZ75748.1 - 0.00061 20.0 5.6 0.011 16.1 3.9 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 AJZ75748.1 - 0.0063 16.9 7.0 0.32 11.4 1.7 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain DUF3000 PF11452.3 AJZ75749.1 - 0.049 12.8 0.1 0.049 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) Beta-Casp PF10996.3 AJZ75750.1 - 9.4e-23 80.5 0.0 1.8e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 AJZ75750.1 - 2.4e-12 46.8 0.0 5.2e-12 45.7 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AJZ75750.1 - 6.9e-12 45.4 0.3 3.8e-11 43.0 0.2 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 AJZ75750.1 - 5.6e-11 42.0 0.1 2.2e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 AJZ75750.1 - 0.0012 18.6 0.0 0.0033 17.1 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain OGG_N PF07934.7 AJZ75751.1 - 7.6e-13 48.4 0.4 1e-11 44.8 0.3 2.3 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 AJZ75751.1 - 3.1e-11 43.5 0.0 5.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_2 PF12826.2 AJZ75751.1 - 0.0097 15.7 0.1 0.035 13.9 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.18 AJZ75751.1 - 0.054 13.2 0.0 0.64 9.8 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Copper-bind PF00127.15 AJZ75752.1 - 1.9e-08 34.4 0.1 2.7e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJZ75752.1 - 0.0047 16.7 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Cytochrom_B_N_2 PF13631.1 AJZ75753.1 - 2.7e-24 85.8 8.8 2.7e-24 85.8 6.1 4.0 3 1 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 AJZ75753.1 - 5.5e-09 36.1 1.1 5.5e-09 36.1 0.8 3.5 4 2 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD XhlA PF10779.4 AJZ75753.1 - 5.4 7.0 5.5 2.7 7.9 0.1 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Rieske PF00355.21 AJZ75754.1 - 7.4e-09 35.0 0.0 1.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain TAT_signal PF10518.4 AJZ75754.1 - 0.00085 19.1 0.5 0.00085 19.1 0.3 1.9 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.4 AJZ75754.1 - 0.0089 15.1 0.1 0.02 14.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Reo_sigmaC PF04582.7 AJZ75755.1 - 0.00035 19.8 4.7 0.00052 19.3 3.2 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein CCDC144C PF14915.1 AJZ75755.1 - 0.0019 17.1 0.2 0.0027 16.6 0.1 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region EMP24_GP25L PF01105.19 AJZ75755.1 - 0.002 17.8 0.2 0.0044 16.7 0.0 1.6 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD Baculo_PEP_C PF04513.7 AJZ75755.1 - 0.0028 17.4 2.1 0.0056 16.5 1.5 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.2 AJZ75755.1 - 0.0049 16.2 0.4 0.0072 15.6 0.3 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain A2M_N PF01835.14 AJZ75755.1 - 0.0095 16.1 0.1 0.09 13.0 0.1 2.2 2 0 0 2 2 2 1 MG2 domain NPV_P10 PF05531.7 AJZ75755.1 - 0.026 14.7 1.2 1.3 9.2 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 AJZ75755.1 - 0.027 13.4 0.0 0.038 12.9 0.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 AJZ75755.1 - 0.039 13.7 0.5 0.11 12.3 0.4 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 AJZ75755.1 - 0.081 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFT57 PF10498.4 AJZ75755.1 - 0.086 11.5 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-F_leu_zip PF10473.4 AJZ75755.1 - 0.12 12.1 0.2 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 AJZ75755.1 - 0.12 11.7 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein IncA PF04156.9 AJZ75755.1 - 0.13 11.8 0.1 0.13 11.8 0.1 1.7 1 1 1 2 2 2 0 IncA protein TBPIP PF07106.8 AJZ75755.1 - 0.18 11.3 0.2 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cna_B PF05738.8 AJZ75755.1 - 0.2 11.4 2.1 0.46 10.2 0.2 2.3 2 0 0 2 2 2 0 Cna protein B-type domain ThiF PF00899.16 AJZ75757.1 - 1.1e-44 151.6 0.5 1.9e-44 150.7 0.4 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 AJZ75757.1 - 8.2e-17 60.5 0.1 1.4e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain ThiS PF02597.15 AJZ75757.1 - 8.6e-10 38.9 0.0 2.4e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 ThiS family Shikimate_DH PF01488.15 AJZ75757.1 - 0.0013 18.8 0.2 0.0042 17.1 0.1 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 AJZ75757.1 - 0.067 12.3 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AJZ75757.1 - 0.07 13.5 0.2 1.6 9.2 0.1 2.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 AJZ75757.1 - 0.07 13.3 0.3 0.24 11.6 0.1 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding PALP PF00291.20 AJZ75758.1 - 4.2e-63 213.3 0.4 4.9e-63 213.1 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PRA-CH PF01502.13 AJZ75759.1 - 4.4e-35 119.1 0.1 5.5e-35 118.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase His_biosynth PF00977.16 AJZ75760.1 - 8.7e-83 277.0 0.7 1e-82 276.8 0.5 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.12 AJZ75760.1 - 1.4e-07 30.6 0.1 0.00048 19.0 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 AJZ75760.1 - 7e-06 25.2 0.1 0.029 13.5 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase/TENI NMO PF03060.10 AJZ75760.1 - 2.2e-05 23.7 0.3 0.017 14.2 0.0 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.9 AJZ75760.1 - 0.00026 20.1 0.2 0.16 11.0 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG PcrB PF01884.12 AJZ75760.1 - 0.0024 17.1 0.0 0.0053 16.0 0.0 1.5 1 0 0 1 1 1 1 PcrB family DHO_dh PF01180.16 AJZ75760.1 - 0.004 16.1 0.0 0.025 13.5 0.0 1.9 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase IMPDH PF00478.20 AJZ75760.1 - 0.014 14.3 0.2 0.23 10.3 0.1 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.15 AJZ75760.1 - 0.014 13.9 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain His_biosynth PF00977.16 AJZ75761.1 - 2.2e-67 226.7 2.3 2.4e-67 226.5 1.6 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein IGPS PF00218.16 AJZ75761.1 - 1.2e-06 27.7 0.1 0.0069 15.4 0.0 2.9 2 1 1 3 3 3 2 Indole-3-glycerol phosphate synthase NMO PF03060.10 AJZ75761.1 - 1.7e-06 27.4 0.1 0.012 14.7 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase PcrB PF01884.12 AJZ75761.1 - 0.0013 18.0 1.5 0.46 9.7 0.0 2.7 2 1 1 3 3 3 2 PcrB family ThiG PF05690.9 AJZ75761.1 - 0.0057 15.7 0.2 2 7.4 0.0 2.1 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Ribul_P_3_epim PF00834.14 AJZ75761.1 - 0.033 13.3 0.9 1.7 7.6 0.0 3.0 2 1 1 3 3 3 0 Ribulose-phosphate 3 epimerase family NanE PF04131.9 AJZ75761.1 - 0.043 12.7 0.1 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Trp_syntA PF00290.15 AJZ75761.1 - 0.06 11.8 0.4 3.8 5.9 0.0 2.7 2 1 1 3 3 3 0 Tryptophan synthase alpha chain Dus PF01207.12 AJZ75761.1 - 0.11 11.3 0.4 7.2 5.3 0.1 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) GATase PF00117.23 AJZ75762.1 - 2.9e-32 111.6 0.0 3.3e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AJZ75762.1 - 0.0001 21.8 0.0 0.0007 19.0 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.14 AJZ75762.1 - 0.00023 20.8 0.0 0.0028 17.3 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 AJZ75762.1 - 0.0026 17.3 0.0 0.0047 16.5 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain IGPD PF00475.13 AJZ75763.1 - 5.8e-50 168.9 0.6 8.3e-50 168.4 0.4 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF916 PF06030.7 AJZ75763.1 - 0.024 14.4 0.0 0.21 11.3 0.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF916) SinI PF08671.5 AJZ75763.1 - 0.15 11.5 0.2 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 Anti-repressor SinI Hydrolase PF00702.21 AJZ75764.1 - 3.4e-07 30.8 0.0 6.8e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AJZ75764.1 - 5.6e-05 23.4 0.1 0.084 13.0 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.2 AJZ75764.1 - 0.00014 22.0 0.0 0.00023 21.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AJZ75764.1 - 0.0028 17.3 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_phosphat_B PF03767.9 AJZ75764.1 - 0.046 13.0 1.4 0.14 11.4 0.1 2.0 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_6 PF13344.1 AJZ75764.1 - 0.11 12.3 0.9 0.55 10.1 0.1 2.4 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.16 AJZ75765.1 - 1.7e-46 158.8 0.0 1.9e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 AJZ75765.1 - 1.8e-06 26.9 0.0 2.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Allinase HTH_22 PF13309.1 AJZ75765.1 - 0.048 13.4 0.6 0.19 11.5 0.1 2.3 2 0 0 2 2 2 0 HTH domain Aminotran_5 PF00266.14 AJZ75765.1 - 0.071 11.8 0.0 0.18 10.4 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V S6PP PF05116.8 AJZ75765.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Histidinol_dh PF00815.15 AJZ75766.1 - 3e-137 457.6 6.5 3.3e-137 457.4 4.5 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase HisG PF01634.13 AJZ75767.1 - 3.4e-39 134.0 0.1 4.5e-39 133.6 0.1 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 AJZ75767.1 - 1.2e-14 54.0 0.0 2.9e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain HMG-CoA_red PF00368.13 AJZ75768.1 - 4.9e-79 265.6 7.3 8e-79 264.9 5.0 1.3 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase GSDH PF07995.6 AJZ75769.1 - 2.3e-83 280.0 0.0 3.1e-83 279.5 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.6 AJZ75769.1 - 0.0007 19.3 0.1 5.1 7.4 0.0 4.1 3 0 0 3 3 3 1 Two component regulator propeller Tachylectin PF14517.1 AJZ75769.1 - 0.068 12.4 0.0 2.2 7.5 0.0 2.4 2 1 0 2 2 2 0 Tachylectin DUF1743 PF08489.6 AJZ75770.1 - 4.3e-36 123.2 0.0 1.2e-35 121.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1743) tRNA_anti-codon PF01336.20 AJZ75770.1 - 0.08 12.8 0.2 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain ProRS-C_1 PF09180.6 AJZ75770.1 - 0.14 12.0 2.0 0.4 10.6 0.8 2.2 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal C1_1 PF00130.17 AJZ75770.1 - 0.21 11.3 2.9 0.36 10.5 2.0 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 AJZ75770.1 - 0.26 11.1 2.4 0.44 10.3 1.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon Diphthamide_syn PF01866.12 AJZ75771.1 - 1.9e-77 260.5 0.0 2.2e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF2777 PF10949.3 AJZ75772.1 - 0.066 12.8 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) hSH3 PF14603.1 AJZ75772.1 - 0.072 13.1 0.5 0.16 11.9 0.3 1.5 1 1 0 1 1 1 0 Helically-extended SH3 domain ECR1_N PF14382.1 AJZ75773.1 - 2e-05 23.7 0.0 3.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Prok-RING_1 PF14446.1 AJZ75773.1 - 0.0055 16.4 1.0 0.013 15.2 0.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 NB PF04159.8 AJZ75773.1 - 0.007 16.0 2.3 0.017 14.8 0.4 2.2 1 1 1 3 3 3 1 NB glycoprotein EXOSC1 PF10447.4 AJZ75773.1 - 0.037 13.9 0.1 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 OrfB_Zn_ribbon PF07282.6 AJZ75773.1 - 0.059 13.0 1.2 0.059 13.0 0.8 1.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain VP9 PF09625.5 AJZ75773.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 VP9 protein zf-Mss51 PF13824.1 AJZ75773.1 - 0.13 12.1 1.2 0.23 11.3 0.8 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_RNApol_7kD PF03604.8 AJZ75773.1 - 0.24 10.8 2.0 0.69 9.4 1.4 1.8 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 AJZ75773.1 - 0.25 11.0 1.2 0.43 10.2 0.8 1.6 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family PDT PF00800.13 AJZ75774.1 - 2e-57 193.6 0.0 2.6e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 AJZ75774.1 - 0.00011 21.5 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain DUF4384 PF14326.1 AJZ75774.1 - 0.021 14.6 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) IMPDH PF00478.20 AJZ75776.1 - 9.1e-137 455.6 6.5 1e-136 455.4 4.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 AJZ75776.1 - 1.6e-26 91.7 0.5 6e-12 45.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 AJZ75776.1 - 7.5e-11 41.7 7.9 9.9e-09 34.7 5.5 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 AJZ75776.1 - 7.1e-09 34.9 3.2 1.1e-08 34.3 1.7 1.8 2 1 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 AJZ75776.1 - 1.5e-05 24.3 1.8 0.012 14.8 0.1 2.6 1 1 1 2 2 2 2 Histidine biosynthesis protein DHO_dh PF01180.16 AJZ75776.1 - 0.00023 20.2 3.5 0.002 17.1 0.3 2.4 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase B12-binding PF02310.14 AJZ75776.1 - 0.0071 16.2 0.2 0.018 14.8 0.2 1.7 1 0 0 1 1 1 1 B12 binding domain Glu_synthase PF01645.12 AJZ75776.1 - 0.0089 14.9 2.2 0.017 14.0 1.5 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 AJZ75776.1 - 0.013 14.5 0.4 0.04 12.9 0.1 2.0 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG Pterin_bind PF00809.17 AJZ75777.1 - 5.1e-36 124.0 0.1 1.1e-35 122.9 0.1 1.6 1 1 0 1 1 1 1 Pterin binding enzyme RuvC PF02075.12 AJZ75778.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC Lge1 PF11488.3 AJZ75778.1 - 0.12 12.5 1.7 0.27 11.4 1.2 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 IATP PF04568.7 AJZ75778.1 - 0.13 12.2 1.8 0.32 11.0 1.2 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP zf-C4H2 PF10146.4 AJZ75778.1 - 7.5 6.5 8.4 0.61 10.0 1.9 1.8 1 1 0 2 2 2 0 Zinc finger-containing protein DUF2291 PF10054.4 AJZ75779.1 - 0.065 12.5 0.1 0.095 11.9 0.1 1.3 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) ETRAMP PF09716.5 AJZ75779.1 - 0.23 11.4 2.4 0.55 10.2 1.7 1.7 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF16 PF01519.11 AJZ75779.1 - 0.46 10.7 6.2 0.76 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 OEP PF02321.13 AJZ75780.1 - 0.069 12.7 10.3 0.041 13.4 2.6 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein Neur_chan_memb PF02932.11 AJZ75780.1 - 0.1 12.4 3.6 0.11 12.3 2.5 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TP53IP5 PF15331.1 AJZ75780.1 - 0.15 11.9 8.8 0.19 11.6 6.1 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF743 PF05332.6 AJZ75780.1 - 0.61 10.0 4.9 0.24 11.3 0.9 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF743) ROK PF00480.15 AJZ75781.1 - 5.4e-49 166.4 4.1 7.3e-49 166.0 2.9 1.2 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.15 AJZ75781.1 - 0.00012 21.4 1.2 0.0015 17.8 0.8 2.3 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hydant_A_N PF05378.8 AJZ75781.1 - 0.0012 18.4 0.2 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region FGGY_N PF00370.16 AJZ75781.1 - 0.044 13.1 0.1 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Cpn60_TCP1 PF00118.19 AJZ75782.1 - 9.8e-165 548.8 15.8 1.2e-164 548.5 11.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L44 PF00935.14 AJZ75783.1 - 4e-25 87.6 6.9 4e-25 87.6 4.8 1.3 2 0 0 2 2 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.6 AJZ75783.1 - 3.9e-05 23.3 2.5 0.002 17.8 0.0 2.1 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like zf-ISL3 PF14690.1 AJZ75783.1 - 0.0003 20.7 2.2 0.13 12.3 0.1 2.3 2 0 0 2 2 2 2 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Cys_rich_KTR PF14205.1 AJZ75783.1 - 0.00088 18.6 4.6 0.066 12.6 0.2 2.3 2 0 0 2 2 2 2 Cysteine-rich KTR zf-ribbon_3 PF13248.1 AJZ75783.1 - 0.0066 15.6 1.5 1.9 7.8 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain zf-TFIIB PF13453.1 AJZ75783.1 - 0.022 13.9 2.7 0.27 10.4 1.9 2.1 1 1 1 2 2 2 0 Transcription factor zinc-finger Zn_Tnp_IS1595 PF12760.2 AJZ75783.1 - 0.035 13.9 0.9 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF329 PF03884.9 AJZ75783.1 - 0.036 13.6 2.5 1.7 8.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF329) Zn-ribbon_8 PF09723.5 AJZ75783.1 - 0.039 13.9 2.6 5.1 7.1 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS91 PF14319.1 AJZ75783.1 - 0.041 13.4 1.5 3.8 7.0 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-C4_Topoisom PF01396.14 AJZ75783.1 - 0.048 13.1 2.2 3.2 7.3 0.1 2.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Ribosomal_L33 PF00471.15 AJZ75783.1 - 0.048 13.9 1.8 0.048 13.9 1.2 2.5 2 0 0 2 2 2 0 Ribosomal protein L33 zf-DNA_Pol PF08996.5 AJZ75783.1 - 0.078 12.3 0.7 0.93 8.8 0.1 2.0 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-Di19 PF05605.7 AJZ75783.1 - 0.13 12.4 0.8 5.7 7.1 0.1 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 AJZ75783.1 - 0.13 11.8 3.5 5.9 6.5 0.3 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 AJZ75783.1 - 0.14 12.0 7.1 0.62 9.9 4.9 1.9 1 1 0 1 1 1 0 Double zinc ribbon Salp15 PF12115.3 AJZ75783.1 - 0.19 11.9 2.0 0.16 12.1 0.4 1.6 1 1 1 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation C1_4 PF07975.7 AJZ75783.1 - 0.2 11.6 2.5 0.94 9.5 0.1 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain zinc_ribbon_5 PF13719.1 AJZ75783.1 - 0.29 10.7 6.3 0.74 9.4 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 AJZ75783.1 - 0.35 10.5 4.8 2.4 7.8 0.6 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-DNL PF05180.7 AJZ75783.1 - 0.36 10.5 3.0 1.2 8.8 0.3 2.2 2 0 0 2 2 2 0 DNL zinc finger Elf1 PF05129.8 AJZ75783.1 - 0.37 10.5 5.1 0.44 10.2 0.6 2.2 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_2 PF13240.1 AJZ75783.1 - 0.39 10.2 8.0 1.5 8.4 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Integrase_Zn PF02022.14 AJZ75783.1 - 0.41 10.1 2.7 12 5.4 0.4 2.3 2 0 0 2 2 2 0 Integrase Zinc binding domain zf-LITAF-like PF10601.4 AJZ75783.1 - 0.43 10.4 2.8 5.3 6.9 0.1 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF2296 PF10058.4 AJZ75783.1 - 0.43 10.3 2.0 5.3 6.8 0.1 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) PHD PF00628.24 AJZ75783.1 - 0.52 10.0 3.0 3.6 7.3 0.2 2.2 2 0 0 2 2 2 0 PHD-finger zf-UDP PF14569.1 AJZ75783.1 - 0.56 9.9 5.2 4.5 7.1 0.2 2.3 2 1 0 2 2 2 0 Zinc-binding RING-finger Tnp_zf-ribbon_2 PF13842.1 AJZ75783.1 - 0.57 10.6 7.1 7.2 7.1 0.2 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-C3HC4_3 PF13920.1 AJZ75783.1 - 0.8 9.4 3.6 11 5.8 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.1 AJZ75783.1 - 1.5 8.5 8.4 2 8.1 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF1610 PF07754.6 AJZ75783.1 - 2.5 8.2 5.5 6.6 6.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) WCCH PF03716.9 AJZ75783.1 - 8.1 6.0 8.2 0.21 11.0 0.6 2.1 2 0 0 2 2 2 0 WCCH motif Ribosomal_S27e PF01667.12 AJZ75784.1 - 2.1e-16 59.1 1.9 2.3e-16 59.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 AJZ75784.1 - 1.4e-06 27.5 1.2 1.9e-06 27.0 0.8 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding DUF4206 PF13901.1 AJZ75784.1 - 0.0069 15.9 0.5 0.0073 15.8 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) zf-ribbon_3 PF13248.1 AJZ75784.1 - 0.0083 15.3 1.5 0.47 9.7 0.2 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_6 PF14599.1 AJZ75784.1 - 0.012 15.4 1.5 0.017 14.9 1.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon Zn_Tnp_IS91 PF14319.1 AJZ75784.1 - 0.015 14.8 0.4 0.016 14.6 0.3 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain DZR PF12773.2 AJZ75784.1 - 0.028 14.2 1.9 0.046 13.5 1.3 1.4 1 1 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 AJZ75784.1 - 0.028 13.8 3.9 0.23 10.9 2.7 2.0 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.1 AJZ75784.1 - 0.029 14.0 5.2 1.4 8.7 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AJZ75784.1 - 0.034 13.7 5.2 1.5 8.4 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.4 AJZ75784.1 - 0.047 13.4 0.2 0.053 13.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-CHY PF05495.7 AJZ75784.1 - 0.056 13.6 1.5 0.066 13.3 1.1 1.1 1 0 0 1 1 1 0 CHY zinc finger zf-trcl PF13451.1 AJZ75784.1 - 0.076 12.6 1.5 8 6.1 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain HECT_2 PF09814.4 AJZ75784.1 - 0.11 11.2 0.3 0.12 11.0 0.2 1.2 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding YhfH PF14149.1 AJZ75784.1 - 0.19 11.5 2.3 0.77 9.5 0.0 2.1 2 0 0 2 2 2 0 YhfH-like protein DUF3133 PF11331.3 AJZ75784.1 - 0.25 10.9 4.6 2.5 7.7 0.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3133) zf-AN1 PF01428.11 AJZ75784.1 - 0.27 11.1 3.3 2.3 8.1 0.1 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger zf-H2C2_2 PF13465.1 AJZ75784.1 - 0.37 11.1 2.6 6.7 7.2 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double domain TFIIS_C PF01096.13 AJZ75784.1 - 0.39 10.3 5.9 35 4.1 4.1 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) A2L_zn_ribbon PF08792.5 AJZ75784.1 - 0.4 10.2 4.4 1.4 8.4 3.0 1.8 1 1 0 1 1 1 0 A2L zinc ribbon domain DUF3797 PF12677.2 AJZ75784.1 - 0.89 9.2 4.9 5 6.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-BED PF02892.10 AJZ75784.1 - 1.2 8.9 5.1 3.4 7.4 0.2 2.2 1 1 1 2 2 2 0 BED zinc finger Eapp_C PF10238.4 AJZ75784.1 - 2 8.3 5.5 7.8 6.3 0.4 2.0 1 1 1 2 2 2 0 E2F-associated phosphoprotein DUF2082 PF09855.4 AJZ75784.1 - 2.9 7.7 7.3 3.9 7.3 0.7 2.2 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-C2H2_3 PF13878.1 AJZ75784.1 - 6 6.5 8.9 4.6 6.8 0.6 2.2 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO NTP_transf_3 PF12804.2 AJZ75785.1 - 4e-14 53.0 0.0 4.8e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 AJZ75785.1 - 2.9e-07 30.2 0.0 3.8e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 AJZ75785.1 - 1.2e-05 25.0 0.2 1.9e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 Cytidylyltransferase RE_Eco47II PF09553.5 AJZ75785.1 - 0.0098 15.0 0.1 0.013 14.6 0.1 1.1 1 0 0 1 1 1 1 Eco47II restriction endonuclease NTP_transferase PF00483.18 AJZ75785.1 - 0.019 14.2 0.1 0.056 12.7 0.1 1.8 1 1 0 1 1 1 0 Nucleotidyl transferase CobD_Cbib PF03186.8 AJZ75786.1 - 2.6e-92 309.0 0.2 3.1e-92 308.7 0.2 1.0 1 0 0 1 1 1 1 CobD/Cbib protein Halogen_Hydrol PF10112.4 AJZ75786.1 - 0.068 12.5 0.5 0.12 11.7 0.4 1.4 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF3784 PF12650.2 AJZ75786.1 - 7.7 6.5 10.2 0.3 11.0 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) CbiA PF01656.18 AJZ75787.1 - 2.1e-30 105.5 0.1 2.6e-30 105.2 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 AJZ75787.1 - 9.6e-20 71.0 0.0 2.9e-19 69.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 AJZ75787.1 - 6.7e-07 29.0 0.0 0.00018 21.2 0.0 2.5 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 AJZ75787.1 - 3.5e-06 26.8 0.0 1.6e-05 24.7 0.0 2.1 2 1 2 4 4 4 1 NTPase SRP54 PF00448.17 AJZ75787.1 - 0.00026 20.4 1.5 0.057 12.8 0.1 2.5 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain AAA_23 PF13476.1 AJZ75787.1 - 0.00081 19.7 1.3 0.0032 17.8 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AJZ75787.1 - 0.0049 17.6 0.1 0.034 14.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain YhjQ PF06564.7 AJZ75787.1 - 0.0053 16.1 0.0 0.01 15.2 0.0 1.6 1 1 0 1 1 1 1 YhjQ protein VirC1 PF07015.6 AJZ75787.1 - 0.0063 15.6 0.0 0.015 14.3 0.0 1.6 1 0 0 1 1 1 1 VirC1 protein AAA_31 PF13614.1 AJZ75787.1 - 0.0063 16.4 0.1 0.036 14.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 AJZ75787.1 - 0.0065 16.7 0.1 0.015 15.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 AJZ75787.1 - 0.016 15.7 0.3 7.1 7.1 0.0 2.6 3 0 0 3 3 2 0 Miro-like protein AAA_18 PF13238.1 AJZ75787.1 - 0.02 15.2 0.0 0.15 12.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 AJZ75787.1 - 0.025 14.0 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 AJZ75787.1 - 0.026 14.0 0.1 0.049 13.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 AJZ75787.1 - 0.038 13.5 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 AJZ75787.1 - 0.047 13.1 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CTP_synth_N PF06418.9 AJZ75787.1 - 0.056 12.5 0.1 0.22 10.6 0.1 1.9 2 0 0 2 2 2 0 CTP synthase N-terminus APS_kinase PF01583.15 AJZ75787.1 - 0.062 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase FNIP_C PF14638.1 AJZ75787.1 - 0.073 12.4 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 Folliculin-interacting protein C-terminus Aminotran_1_2 PF00155.16 AJZ75788.1 - 1.6e-51 175.3 0.0 2e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Semialdhyde_dhC PF02774.13 AJZ75789.1 - 1.8e-37 129.0 0.0 3e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 AJZ75789.1 - 5.5e-29 100.9 0.0 1.1e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 AJZ75789.1 - 1.3e-05 24.6 0.9 0.00031 20.2 0.0 2.6 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.11 AJZ75789.1 - 0.0064 17.0 0.1 0.022 15.3 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ldh_1_N PF00056.18 AJZ75789.1 - 0.048 13.4 0.0 0.25 11.1 0.0 2.1 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.15 AJZ75789.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AsnC_trans_reg PF01037.16 AJZ75790.1 - 1.6e-09 37.3 0.0 1.9e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 AsnC family UbiA PF01040.13 AJZ75791.1 - 7.7e-23 81.0 17.8 1e-22 80.5 12.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family VIT1 PF01988.14 AJZ75791.1 - 0.02 14.4 1.8 0.02 14.4 1.3 3.0 3 1 1 4 4 4 0 VIT family DUF3681 PF12442.3 AJZ75791.1 - 3.7 7.7 9.7 13 5.9 1.8 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3681) HTH_CodY PF08222.6 AJZ75792.1 - 3.5e-05 23.0 0.0 6.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 CodY helix-turn-helix domain HTH_11 PF08279.7 AJZ75792.1 - 0.0036 16.9 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.1 AJZ75792.1 - 0.0051 16.1 0.0 0.0087 15.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_10 PF04967.7 AJZ75792.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_20 PF12840.2 AJZ75792.1 - 0.061 13.1 0.0 0.094 12.5 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_45 PF14947.1 AJZ75792.1 - 0.13 12.1 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix ParB PF08775.5 AJZ75794.1 - 0.001 19.3 5.4 0.0011 19.2 3.8 1.0 1 0 0 1 1 1 1 ParB family SseC PF04888.7 AJZ75794.1 - 0.0022 17.4 2.0 0.0024 17.2 1.4 1.0 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Tropomyosin PF00261.15 AJZ75794.1 - 0.0054 15.8 10.2 0.027 13.5 7.0 1.8 1 1 0 1 1 1 1 Tropomyosin FliD_C PF07195.7 AJZ75794.1 - 0.0065 15.7 1.1 0.0065 15.7 0.8 1.5 1 1 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus ApoC-I PF04691.7 AJZ75794.1 - 0.013 15.1 2.1 0.028 14.1 1.3 1.8 1 1 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) ORF6C PF10552.4 AJZ75794.1 - 0.015 14.9 2.2 0.019 14.6 1.5 1.2 1 0 0 1 1 1 0 ORF6C domain ACCA PF03255.9 AJZ75794.1 - 0.023 14.2 3.1 0.027 14.0 2.2 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit E2_bind PF08825.5 AJZ75794.1 - 0.026 14.2 2.0 4.5 7.0 0.0 2.6 1 1 2 3 3 3 0 E2 binding domain PIN_2 PF10130.4 AJZ75794.1 - 0.057 13.4 3.1 0.065 13.2 2.2 1.0 1 0 0 1 1 1 0 PIN domain MitMem_reg PF13012.1 AJZ75794.1 - 0.06 13.4 2.2 0.07 13.2 1.5 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Fe_bilin_red PF05996.7 AJZ75794.1 - 0.068 12.6 0.2 0.071 12.5 0.2 1.0 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase Phage_GPO PF05929.6 AJZ75794.1 - 0.083 12.1 4.9 0.084 12.1 3.4 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Tape_meas_lam_C PF09718.5 AJZ75794.1 - 0.084 12.8 0.1 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) RmuC PF02646.11 AJZ75794.1 - 0.094 11.5 2.5 0.1 11.4 1.7 1.1 1 0 0 1 1 1 0 RmuC family CENP-H PF05837.7 AJZ75794.1 - 0.14 12.3 6.8 0.15 12.2 4.7 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ScpA_ScpB PF02616.9 AJZ75794.1 - 0.16 11.5 4.3 0.17 11.4 3.0 1.0 1 0 0 1 1 1 0 ScpA/B protein YvrJ PF12841.2 AJZ75794.1 - 0.16 11.2 0.3 0.38 10.0 0.2 1.8 1 1 0 1 1 1 0 YvrJ protein family Mod_r PF07200.8 AJZ75794.1 - 0.16 11.8 8.4 0.17 11.7 5.8 1.0 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Uds1 PF15456.1 AJZ75794.1 - 0.16 11.9 4.2 0.2 11.6 2.9 1.1 1 0 0 1 1 1 0 Up-regulated During Septation AAA_32 PF13654.1 AJZ75794.1 - 0.17 10.5 3.6 0.18 10.4 2.5 1.1 1 0 0 1 1 1 0 AAA domain EzrA PF06160.7 AJZ75794.1 - 0.17 10.0 8.2 0.17 10.0 5.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Tropomyosin_1 PF12718.2 AJZ75794.1 - 0.2 11.4 11.8 0.54 10.0 8.1 1.6 1 1 0 1 1 1 0 Tropomyosin like Spc7 PF08317.6 AJZ75794.1 - 0.21 10.2 8.0 0.23 10.0 5.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.7 AJZ75794.1 - 0.21 11.8 1.2 0.5 10.6 0.3 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2802 PF10975.3 AJZ75794.1 - 0.22 11.3 1.4 0.59 9.9 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) DUF724 PF05266.9 AJZ75794.1 - 0.24 10.9 5.2 0.3 10.7 3.5 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Histone_HNS PF00816.16 AJZ75794.1 - 0.3 11.6 3.6 0.38 11.2 2.5 1.3 1 0 0 1 1 1 0 H-NS histone family Fib_alpha PF08702.5 AJZ75794.1 - 0.37 10.9 3.5 0.56 10.3 2.4 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 AJZ75794.1 - 0.38 11.1 3.0 2 8.8 2.1 2.0 1 1 0 1 1 1 0 SlyX Nup54 PF13874.1 AJZ75794.1 - 0.39 10.3 2.7 0.5 10.0 1.8 1.3 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Sigma_reg_C PF13791.1 AJZ75794.1 - 0.43 10.5 3.2 0.47 10.4 2.2 1.1 1 0 0 1 1 1 0 Sigma factor regulator C-terminal TMF_DNA_bd PF12329.3 AJZ75794.1 - 0.44 10.3 10.7 2.3 8.0 7.4 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SPX PF03105.14 AJZ75794.1 - 0.52 10.0 5.0 0.62 9.7 3.5 1.2 1 0 0 1 1 1 0 SPX domain DUF972 PF06156.8 AJZ75794.1 - 0.53 10.6 7.0 0.95 9.8 4.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Packaging_FI PF14000.1 AJZ75794.1 - 0.58 10.3 11.1 3.6 7.8 2.3 2.1 1 1 0 2 2 2 0 DNA packaging protein FI BMFP PF04380.8 AJZ75794.1 - 0.58 10.3 6.2 10 6.3 0.1 2.7 1 1 2 3 3 3 0 Membrane fusogenic activity TMF_TATA_bd PF12325.3 AJZ75794.1 - 0.62 9.8 9.2 0.69 9.6 6.4 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FTCD_C PF04961.7 AJZ75794.1 - 0.65 9.3 3.6 0.71 9.2 2.5 1.1 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF1664 PF07889.7 AJZ75794.1 - 0.69 9.7 3.1 0.99 9.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 AJZ75794.1 - 1.2 9.2 6.8 1.7 8.6 4.7 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Ax_dynein_light PF10211.4 AJZ75794.1 - 1.3 8.8 7.2 2.2 8.0 4.6 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain DUF3347 PF11827.3 AJZ75794.1 - 1.3 8.9 4.3 1.3 8.9 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DUF342 PF03961.8 AJZ75794.1 - 1.7 6.9 6.8 1.9 6.8 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 AJZ75794.1 - 1.8 7.4 4.7 2 7.2 3.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Snapin_Pallidin PF14712.1 AJZ75794.1 - 2 8.7 6.2 2.3 8.6 1.7 2.0 1 1 1 2 2 2 0 Snapin/Pallidin IncA PF04156.9 AJZ75794.1 - 2.1 7.9 8.5 3 7.4 5.9 1.2 1 0 0 1 1 1 0 IncA protein TBPIP PF07106.8 AJZ75794.1 - 2.2 7.8 7.7 3 7.3 5.3 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PhoU PF01895.14 AJZ75794.1 - 2.2 8.7 5.4 5.3 7.5 2.5 2.1 1 1 1 2 2 2 0 PhoU domain Prefoldin_2 PF01920.15 AJZ75794.1 - 3.1 7.6 11.0 1.3 8.8 3.6 2.1 1 1 1 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.14 AJZ75794.1 - 3.1 5.5 6.4 3.1 5.5 4.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 AJZ75794.1 - 4.1 7.7 10.3 51 4.2 7.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) WD40_alt PF14077.1 AJZ75794.1 - 4.5 6.9 9.2 14 5.4 0.1 2.9 2 1 0 2 2 2 0 Alternative WD40 repeat motif bZIP_2 PF07716.10 AJZ75794.1 - 5.8 6.8 10.3 2.3 8.1 3.7 2.4 1 1 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.10 AJZ75794.1 - 6.4 6.3 8.0 1.9 8.0 2.2 2.0 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 AJZ75794.1 - 7.3 5.5 9.2 7.7 5.4 6.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 XhlA PF10779.4 AJZ75794.1 - 8 6.4 8.7 74 3.3 6.0 2.0 1 1 0 1 1 1 0 Haemolysin XhlA DdrB PF12747.2 AJZ75795.1 - 0.0096 15.6 0.4 0.012 15.3 0.3 1.2 1 0 0 1 1 1 1 DdrB-like protein Borrelia_lipo_2 PF06238.6 AJZ75795.1 - 0.21 11.6 1.4 0.4 10.7 0.8 1.6 1 1 0 1 1 1 0 Borrelia burgdorferi BBR25 lipoprotein DNA_repr_REX1B PF14966.1 AJZ75797.1 - 0.023 15.0 2.8 0.041 14.2 2.0 1.7 1 1 0 1 1 1 0 DNA repair REX1-B rve PF00665.21 AJZ75797.1 - 0.028 14.5 0.3 0.048 13.7 0.2 1.5 1 1 0 1 1 1 0 Integrase core domain Tape_meas_lam_C PF09718.5 AJZ75797.1 - 0.028 14.3 1.7 0.028 14.3 1.1 2.5 3 1 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF4456 PF14644.1 AJZ75797.1 - 0.13 11.4 4.3 0.21 10.8 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) Phasin_2 PF09361.5 AJZ75797.1 - 0.18 11.8 5.5 0.87 9.6 1.2 2.5 2 1 0 2 2 2 0 Phasin protein DUF2524 PF10732.4 AJZ75797.1 - 5.5 7.1 6.7 14 5.8 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) SEC-C PF02810.10 AJZ75798.1 - 0.0011 18.3 5.3 0.0017 17.8 3.7 1.2 1 0 0 1 1 1 1 SEC-C motif DUF2580 PF10824.3 AJZ75798.1 - 0.031 14.6 0.4 0.17 12.2 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2580) TSCPD PF12637.2 AJZ75798.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 TSCPD domain DinI PF06183.8 AJZ75798.1 - 0.11 12.5 0.2 0.37 10.8 0.1 1.8 1 1 0 1 1 1 0 DinI-like family MamL-1 PF09596.5 AJZ75798.1 - 0.23 11.2 0.9 0.87 9.4 0.1 2.0 2 0 0 2 2 2 0 MamL-1 domain rRNA_methylase PF06962.7 AJZ75799.1 - 0.017 14.7 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Putative rRNA methylase P-II PF00543.17 AJZ75800.1 - 2.6e-11 43.8 1.6 3e-11 43.7 1.1 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Nit_Regul_Hom PF10126.4 AJZ75800.1 - 0.0027 17.4 1.6 0.0075 16.0 1.1 1.7 1 1 0 1 1 1 1 Uncharacterized protein, homolog of nitrogen regulatory protein PII DUF190 PF02641.10 AJZ75800.1 - 0.0051 16.6 0.2 0.0069 16.2 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1993 Gp_dh_C PF02800.15 AJZ75800.1 - 0.049 13.0 0.1 0.067 12.6 0.1 1.2 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain CBS PF00571.23 AJZ75800.1 - 0.11 12.2 1.5 6.6 6.6 0.1 2.5 2 1 1 3 3 3 0 CBS domain CBS PF00571.23 AJZ75801.1 - 2.7e-46 155.1 12.6 2.4e-13 49.6 0.1 4.2 4 0 0 4 4 4 4 CBS domain Ammonium_transp PF00909.16 AJZ75802.1 - 7.2e-112 373.7 30.8 8.1e-112 373.5 21.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family P-II PF00543.17 AJZ75803.1 - 6e-13 49.1 0.3 7.5e-13 48.8 0.2 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Usp PF00582.21 AJZ75805.1 - 4.1e-32 111.2 0.0 4.8e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family CBS PF00571.23 AJZ75807.1 - 9e-48 159.8 5.1 6.6e-14 51.4 0.0 4.1 4 0 0 4 4 4 4 CBS domain Thioredoxin_2 PF13098.1 AJZ75807.1 - 0.071 13.3 0.1 0.21 11.7 0.0 1.9 2 1 0 2 2 2 0 Thioredoxin-like domain DUF2682 PF10909.3 AJZ75807.1 - 0.084 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) HicB PF05534.7 AJZ75808.1 - 0.0052 16.3 0.3 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 HicB family CBS PF00571.23 AJZ75809.1 - 1.1e-20 73.1 2.4 6.5e-10 38.6 0.1 4.3 4 0 0 4 4 4 4 CBS domain Ribosomal_S30AE PF02482.14 AJZ75809.1 - 0.00044 20.6 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Phenol_hyd_sub PF06099.6 AJZ75809.1 - 0.064 13.1 0.1 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phenol hydroxylase subunit Copper-bind PF00127.15 AJZ75810.1 - 4.3e-07 30.0 0.2 6.3e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJZ75810.1 - 1.6e-05 24.6 0.2 2.6e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain W_rich_C PF07483.6 AJZ75810.1 - 0.0071 16.0 0.3 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 Tryptophan-rich Synechocystis species C-terminal domain adh_short_C2 PF13561.1 AJZ75811.1 - 2.9e-35 122.1 1.9 3.6e-35 121.8 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AJZ75811.1 - 3.6e-25 88.8 0.2 4.6e-25 88.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AJZ75811.1 - 7.2e-08 32.2 0.1 9.7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AJZ75811.1 - 8.3e-06 25.4 2.2 3.8e-05 23.2 1.5 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 AJZ75811.1 - 2e-05 23.8 0.0 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 AJZ75811.1 - 0.017 14.1 0.4 0.052 12.6 0.0 1.9 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.20 AJZ75811.1 - 0.021 14.3 0.3 0.034 13.6 0.2 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NAD_binding_10 PF13460.1 AJZ75811.1 - 0.03 14.3 0.3 0.051 13.5 0.2 1.4 1 1 0 1 1 1 0 NADH(P)-binding PapC_N PF13954.1 AJZ75811.1 - 0.045 13.3 0.1 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 PapC N-terminal domain RmlD_sub_bind PF04321.12 AJZ75811.1 - 0.046 12.6 0.2 0.17 10.7 0.1 1.7 1 1 1 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 AJZ75811.1 - 0.062 12.5 0.3 0.16 11.2 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family Usp PF00582.21 AJZ75812.1 - 7.3e-30 103.9 0.0 8.8e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family PRD_Mga PF08270.6 AJZ75812.1 - 0.079 12.2 0.0 0.097 11.9 0.0 1.1 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain Pribosyltran PF00156.22 AJZ75813.1 - 9.1e-11 41.5 0.2 4.3e-06 26.4 0.0 2.2 1 1 1 2 2 2 2 Phosphoribosyl transferase domain CBS PF00571.23 AJZ75814.1 - 3.6e-30 103.4 5.9 4.9e-16 58.2 0.1 2.1 2 0 0 2 2 2 2 CBS domain DUF2862 PF11061.3 AJZ75814.1 - 0.025 14.2 0.4 0.059 13.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) Usp PF00582.21 AJZ75817.1 - 3.6e-28 98.5 0.0 4.2e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.21 AJZ75818.1 - 1.5e-29 102.9 0.2 1.9e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family F_bP_aldolase PF01116.15 AJZ75818.1 - 0.05 12.6 0.1 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Pribosyltran PF00156.22 AJZ75819.1 - 2.2e-21 75.8 0.0 4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AJZ75819.1 - 2.9e-05 23.3 0.0 4.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 AJZ75819.1 - 5.1e-05 22.6 0.0 7.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase Usp PF00582.21 AJZ75820.1 - 3.4e-30 105.0 0.0 3.8e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family CBS PF00571.23 AJZ75821.1 - 1.8e-25 88.4 1.3 1e-11 44.3 0.0 2.1 2 0 0 2 2 2 2 CBS domain VIT1 PF01988.14 AJZ75822.1 - 1.4e-64 217.5 4.0 1.6e-64 217.3 2.8 1.0 1 0 0 1 1 1 1 VIT family MFS_2 PF13347.1 AJZ75822.1 - 0.26 9.6 11.3 0.015 13.7 2.7 1.9 2 0 0 2 2 2 0 MFS/sugar transport protein IncA PF04156.9 AJZ75822.1 - 1.6 8.3 0.0 1.6 8.3 0.0 2.6 3 0 0 3 3 3 0 IncA protein Calreticulin PF00262.13 AJZ75823.1 - 0.0013 17.4 0.4 0.0018 16.9 0.3 1.2 1 0 0 1 1 1 1 Calreticulin family Syntaxin PF00804.20 AJZ75823.1 - 0.42 10.8 6.5 11 6.2 2.1 3.2 2 1 0 2 2 2 0 Syntaxin DUF3810 PF12725.2 AJZ75823.1 - 1.9 7.3 6.8 1.3 7.8 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) WXG100 PF06013.7 AJZ75823.1 - 4.6 7.3 19.3 6.8 6.7 1.2 4.7 3 1 1 5 5 5 0 Proteins of 100 residues with WXG XPC-binding PF09280.6 AJZ75823.1 - 6.2 6.3 37.7 1.7 8.1 8.0 3.6 1 1 2 3 3 3 0 XPC-binding domain Aminotran_1_2 PF00155.16 AJZ75823.1 - 7.8 5.3 8.4 30 3.4 5.8 1.8 1 1 0 1 1 1 0 Aminotransferase class I and II Cpn60_TCP1 PF00118.19 AJZ75824.1 - 1.2e-168 561.6 18.5 1.4e-168 561.4 12.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.1 AJZ75824.1 - 0.0069 16.2 0.3 0.079 12.8 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3924) Ustilago_mating PF05722.7 AJZ75824.1 - 0.024 13.9 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Ustilago B locus mating-type protein 3H PF02829.9 AJZ75824.1 - 0.36 10.8 3.1 2.6 8.1 0.1 3.5 4 0 0 4 4 4 0 3H domain Ldh_1_C PF02866.13 AJZ75825.1 - 1.8e-29 102.6 0.0 2.6e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 AJZ75825.1 - 2.2e-24 85.8 2.1 5.5e-24 84.5 1.1 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AJZ75825.1 - 7.9e-06 26.0 0.2 1.4e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glyco_hydro_4 PF02056.11 AJZ75825.1 - 2e-05 23.9 1.7 0.0017 17.7 0.0 2.8 2 1 1 3 3 3 1 Family 4 glycosyl hydrolase NAD_Gly3P_dh_N PF01210.18 AJZ75825.1 - 0.0011 18.7 0.3 0.0043 16.7 0.2 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 AJZ75825.1 - 0.0025 18.2 0.6 0.0061 16.9 0.2 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DDE_Tnp_1_assoc PF13808.1 AJZ75825.1 - 0.023 14.3 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 DDE_Tnp_1-associated UDPG_MGDP_dh_N PF03721.9 AJZ75825.1 - 0.042 13.2 2.3 0.3 10.4 1.6 2.1 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 AJZ75825.1 - 0.053 12.4 0.1 0.078 11.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 AJZ75825.1 - 0.17 11.5 1.0 0.37 10.4 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cupredoxin_1 PF13473.1 AJZ75826.1 - 0.00012 21.9 0.2 0.00024 20.9 0.1 1.6 1 1 1 2 2 2 1 Cupredoxin-like domain DUF1905 PF08922.6 AJZ75826.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) FixG_C PF11614.3 AJZ75826.1 - 0.028 14.4 0.2 0.046 13.8 0.1 1.3 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase AA_permease_2 PF13520.1 AJZ75828.1 - 2.7e-55 187.6 57.6 3.2e-55 187.3 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AJZ75828.1 - 2.8e-46 157.8 51.1 3.4e-46 157.5 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 AJZ75828.1 - 6.6e-11 41.3 30.9 1.5e-08 33.6 13.4 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF2152 PF10222.4 AJZ75828.1 - 0.062 11.5 0.1 0.091 10.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) Nramp PF01566.13 AJZ75829.1 - 5.2e-72 242.6 20.7 6.5e-72 242.2 14.4 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF1616 PF07760.6 AJZ75829.1 - 0.0019 17.4 3.4 0.0019 17.4 2.4 2.7 1 1 1 3 3 3 1 Protein of unknown function (DUF1616) Thioredoxin_4 PF13462.1 AJZ75830.1 - 3.5e-30 105.1 0.0 4.3e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 AJZ75830.1 - 9.2e-13 48.1 0.1 1.2e-10 41.2 0.1 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_8 PF13905.1 AJZ75830.1 - 0.00015 21.8 0.2 0.0019 18.2 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 AJZ75830.1 - 0.0016 18.6 0.0 0.0041 17.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain TraG_N PF07916.6 AJZ75831.1 - 4.4 5.6 8.0 4.6 5.5 5.5 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region SelB-wing_2 PF09106.6 AJZ75833.1 - 0.019 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Elongation factor SelB, winged helix zf-C3HC4_3 PF13920.1 AJZ75834.1 - 0.00054 19.5 0.4 0.17 11.5 0.1 2.1 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 AJZ75834.1 - 0.0025 17.8 0.4 0.97 9.6 0.1 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 AJZ75834.1 - 0.0036 16.8 2.2 1.1 8.9 0.1 2.1 2 0 0 2 2 2 2 GAGA factor zinc_ribbon_5 PF13719.1 AJZ75834.1 - 0.01 15.3 0.7 3.2 7.4 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AJZ75834.1 - 0.014 15.0 1.3 3.3 7.4 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Rad50_zn_hook PF04423.9 AJZ75834.1 - 0.016 14.6 3.5 1.1 8.7 0.3 2.3 2 1 0 2 2 2 0 Rad50 zinc hook motif zf-RING_5 PF14634.1 AJZ75834.1 - 0.018 14.7 1.0 2 8.1 0.1 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Sgf11 PF08209.6 AJZ75834.1 - 0.023 14.0 2.4 0.043 13.1 0.1 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DZR PF12773.2 AJZ75834.1 - 0.025 14.3 0.3 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Double zinc ribbon zf-H2C2_2 PF13465.1 AJZ75834.1 - 0.036 14.3 2.4 0.67 10.3 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 AJZ75834.1 - 0.048 13.6 1.3 2.4 8.1 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain DUF329 PF03884.9 AJZ75834.1 - 0.054 13.0 1.9 0.66 9.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-CHY PF05495.7 AJZ75834.1 - 0.071 13.2 0.2 0.089 12.9 0.2 1.2 1 0 0 1 1 1 0 CHY zinc finger DUF2225 PF09986.4 AJZ75834.1 - 0.092 12.1 1.5 2.2 7.6 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C3HC4 PF00097.20 AJZ75834.1 - 0.098 12.3 0.5 2.7 7.7 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 AJZ75834.1 - 0.11 12.0 1.7 4.8 6.8 0.2 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.16 AJZ75834.1 - 0.11 12.4 0.7 2.9 7.8 0.1 2.0 2 0 0 2 2 2 0 IBR domain zf-MIZ PF02891.15 AJZ75834.1 - 0.12 11.8 2.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Zn_Tnp_IS1 PF03811.8 AJZ75834.1 - 0.13 11.7 2.1 4.6 6.8 0.2 2.3 2 0 0 2 2 2 0 InsA N-terminal domain zf-Sec23_Sec24 PF04810.10 AJZ75834.1 - 0.19 11.2 2.3 7.5 6.2 0.1 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.1 AJZ75834.1 - 0.2 11.3 0.4 0.2 11.3 0.3 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type NADH-G_4Fe-4S_3 PF10588.4 AJZ75834.1 - 0.25 10.6 3.0 7.3 5.9 0.2 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF2256 PF10013.4 AJZ75834.1 - 0.38 10.5 2.4 2 8.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DNA_ligase_ZBD PF03119.11 AJZ75834.1 - 0.54 10.0 4.7 8.7 6.1 0.7 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-LITAF-like PF10601.4 AJZ75834.1 - 0.74 9.7 2.9 2 8.3 0.7 2.0 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain UPF0547 PF10571.4 AJZ75834.1 - 0.88 9.3 6.1 3.5 7.4 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_2 PF13639.1 AJZ75834.1 - 1 9.2 5.9 4.9 7.0 0.2 2.2 1 1 2 3 3 3 0 Ring finger domain RRN7 PF11781.3 AJZ75834.1 - 2.8 7.5 4.9 1.6 8.3 0.3 2.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 RHH_1 PF01402.16 AJZ75835.1 - 0.0046 16.7 0.0 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family DUF3816 PF12822.2 AJZ75836.1 - 4.4e-05 23.4 0.6 4.8e-05 23.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) DUF805 PF05656.9 AJZ75836.1 - 0.0029 17.4 0.7 0.0035 17.1 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF805) RseC_MucC PF04246.7 AJZ75836.1 - 0.017 14.6 0.1 0.02 14.4 0.1 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF1275 PF06912.6 AJZ75836.1 - 0.049 12.8 0.1 0.055 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Sigma_reg_N PF13800.1 AJZ75836.1 - 0.066 13.2 1.2 0.15 12.0 0.0 1.8 1 1 1 2 2 2 0 Sigma factor regulator N-terminal MpPF26 PF07666.6 AJZ75836.1 - 0.068 13.0 0.5 3.9 7.3 0.0 2.0 2 0 0 2 2 2 0 M penetrans paralogue family 26 Tic20 PF09685.5 AJZ75836.1 - 0.082 12.8 3.5 0.13 12.2 2.4 1.3 1 1 0 1 1 1 0 Tic20-like protein DUF4064 PF13273.1 AJZ75836.1 - 0.11 12.6 2.0 0.13 12.3 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF996 PF06195.8 AJZ75836.1 - 0.73 9.8 4.5 2.3 8.2 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF996) DUF308 PF03729.8 AJZ75836.1 - 2.6 8.0 11.4 4.2 7.4 0.3 2.1 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF2393 PF09624.5 AJZ75836.1 - 3.2 7.2 5.2 3.3 7.2 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2393) UbiD PF01977.11 AJZ75837.1 - 6.3e-103 344.3 0.2 7.2e-103 344.1 0.1 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Cys_rich_CPCC PF14206.1 AJZ75839.1 - 0.1 12.1 2.5 0.15 11.6 0.2 2.2 2 0 0 2 2 2 0 Cysteine-rich CPCC UPF0081 PF03652.10 AJZ75840.1 - 0.0043 17.1 0.0 0.044 13.8 0.0 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0081) DUF460 PF04312.8 AJZ75840.1 - 0.018 14.5 0.2 0.089 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF460) DUF883 PF05957.8 AJZ75841.1 - 0.00022 21.5 7.0 0.037 14.4 0.5 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Mis14 PF08641.7 AJZ75841.1 - 0.00056 19.9 3.0 0.00067 19.7 2.1 1.2 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Apolipoprotein PF01442.13 AJZ75841.1 - 0.0013 18.2 2.0 0.0021 17.5 1.4 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.13 AJZ75841.1 - 0.0042 16.8 11.4 0.0084 15.9 7.9 1.5 1 1 0 1 1 1 1 ATP synthase B/B' CF(0) DivIVA PF05103.8 AJZ75841.1 - 0.012 15.6 7.8 0.017 15.1 5.4 1.3 1 0 0 1 1 1 0 DivIVA protein DUF1682 PF07946.9 AJZ75841.1 - 0.014 14.2 5.3 0.017 14.0 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CHASE3 PF05227.8 AJZ75841.1 - 0.015 14.9 2.1 0.038 13.6 1.5 1.5 1 1 1 2 2 2 0 CHASE3 domain V-SNARE PF05008.10 AJZ75841.1 - 0.016 15.3 10.1 0.22 11.7 6.3 2.5 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Exonuc_VII_L PF02601.10 AJZ75841.1 - 0.016 14.4 3.9 0.018 14.2 2.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlxA PF14282.1 AJZ75841.1 - 0.017 15.0 10.1 0.022 14.7 7.0 1.3 1 0 0 1 1 1 0 FlxA-like protein AAA_13 PF13166.1 AJZ75841.1 - 0.019 13.4 8.3 0.021 13.2 5.8 1.0 1 0 0 1 1 1 0 AAA domain CsoSCA PF08936.5 AJZ75841.1 - 0.019 13.3 0.8 0.022 13.1 0.6 1.2 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase APP_E2 PF12925.2 AJZ75841.1 - 0.022 14.3 1.9 0.54 9.8 0.2 2.0 1 1 1 2 2 2 0 E2 domain of amyloid precursor protein Mitofilin PF09731.4 AJZ75841.1 - 0.028 13.0 10.7 0.031 12.9 7.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein YPEB PF14620.1 AJZ75841.1 - 0.036 13.0 2.9 0.044 12.7 2.0 1.0 1 0 0 1 1 1 0 YpeB sporulation Tropomyosin_1 PF12718.2 AJZ75841.1 - 0.037 13.8 10.0 0.11 12.2 7.0 1.8 1 1 0 1 1 1 0 Tropomyosin like COG6 PF06419.6 AJZ75841.1 - 0.039 12.0 5.2 0.051 11.7 3.6 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 V-ATPase_G PF03179.10 AJZ75841.1 - 0.044 14.0 8.5 0.071 13.4 5.2 1.9 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF3610 PF12272.3 AJZ75841.1 - 0.05 13.2 1.2 0.066 12.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) DUF972 PF06156.8 AJZ75841.1 - 0.052 13.9 4.6 0.072 13.4 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Tweety PF04906.8 AJZ75841.1 - 0.056 11.8 1.3 0.065 11.6 0.9 1.1 1 0 0 1 1 1 0 Tweety Spc7 PF08317.6 AJZ75841.1 - 0.069 11.7 8.0 0.085 11.5 5.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 AJZ75841.1 - 0.084 12.0 8.2 0.1 11.7 5.7 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein SPX PF03105.14 AJZ75841.1 - 0.13 12.0 5.2 0.15 11.8 3.6 1.1 1 0 0 1 1 1 0 SPX domain Phasin PF05597.6 AJZ75841.1 - 0.13 12.0 8.9 0.3 10.8 1.6 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SBP_bac_7 PF03480.8 AJZ75841.1 - 0.13 11.3 1.9 0.16 11.0 1.3 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Baculo_PEP_C PF04513.7 AJZ75841.1 - 0.13 12.0 3.5 0.27 11.0 1.0 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Duffy_binding PF05424.6 AJZ75841.1 - 0.14 11.9 1.4 0.2 11.4 1.0 1.4 1 1 0 1 1 1 0 Duffy binding domain OmpH PF03938.9 AJZ75841.1 - 0.15 11.9 7.2 0.19 11.6 5.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Muted PF14942.1 AJZ75841.1 - 0.15 11.9 4.0 0.2 11.5 2.8 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein IFT57 PF10498.4 AJZ75841.1 - 0.17 10.6 6.8 0.23 10.1 4.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FlaC_arch PF05377.6 AJZ75841.1 - 0.17 11.8 6.9 0.089 12.7 2.2 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Mnd1 PF03962.10 AJZ75841.1 - 0.17 11.5 5.6 0.21 11.2 3.9 1.1 1 0 0 1 1 1 0 Mnd1 family RmuC PF02646.11 AJZ75841.1 - 0.19 10.5 5.3 0.19 10.5 3.0 1.4 1 1 0 1 1 1 0 RmuC family Peptidase_M41 PF01434.13 AJZ75841.1 - 0.2 11.1 5.1 0.21 11.0 2.8 1.6 1 1 1 2 2 2 0 Peptidase family M41 Phage_Mu_Gam PF07352.7 AJZ75841.1 - 0.22 11.0 8.7 1.2 8.6 0.3 2.0 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein ORF6C PF10552.4 AJZ75841.1 - 0.22 11.2 4.0 0.52 10.0 2.7 1.7 1 1 0 1 1 1 0 ORF6C domain Prominin PF05478.6 AJZ75841.1 - 0.26 8.7 4.9 0.36 8.3 3.4 1.2 1 0 0 1 1 1 0 Prominin DUF3552 PF12072.3 AJZ75841.1 - 0.28 10.3 12.4 0.078 12.1 4.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ISG65-75 PF11727.3 AJZ75841.1 - 0.29 10.1 9.1 0.34 9.9 6.3 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Allexi_40kDa PF05549.6 AJZ75841.1 - 0.29 10.4 3.8 0.38 9.9 2.7 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Spore_III_AB PF09548.5 AJZ75841.1 - 0.29 10.8 3.2 0.78 9.4 1.1 1.8 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Syntaxin PF00804.20 AJZ75841.1 - 0.32 11.1 11.7 0.41 10.8 8.1 1.1 1 0 0 1 1 1 0 Syntaxin NPV_P10 PF05531.7 AJZ75841.1 - 0.37 11.0 5.5 0.99 9.7 3.8 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 AJZ75841.1 - 0.39 10.3 9.4 0.25 10.9 0.3 2.6 1 1 2 3 3 3 0 Prefoldin subunit DUF2408 PF10303.4 AJZ75841.1 - 0.4 10.7 4.4 0.52 10.4 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) TPR_MLP1_2 PF07926.7 AJZ75841.1 - 0.42 10.3 11.2 1.3 8.7 7.8 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Kinetocho_Slk19 PF12709.2 AJZ75841.1 - 0.45 10.6 3.8 0.92 9.6 1.8 2.1 1 1 0 1 1 1 0 Central kinetochore-associated SlyX PF04102.7 AJZ75841.1 - 0.48 10.8 2.2 1.4 9.3 1.6 1.9 1 1 0 1 1 1 0 SlyX Spc24 PF08286.6 AJZ75841.1 - 0.64 9.7 7.2 2.9 7.5 5.0 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Mgr1 PF08602.5 AJZ75841.1 - 0.65 8.9 3.9 0.73 8.7 2.7 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Med4 PF10018.4 AJZ75841.1 - 0.83 9.0 8.3 5.9 6.2 6.0 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Sec2p PF06428.6 AJZ75841.1 - 0.86 9.4 7.8 1.2 9.0 1.4 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF607 PF04678.8 AJZ75841.1 - 0.93 9.3 3.5 4.5 7.1 0.2 2.2 1 1 2 3 3 3 0 Protein of unknown function, DUF607 PKI PF02827.11 AJZ75841.1 - 0.94 9.6 7.2 0.44 10.7 1.0 2.2 1 1 1 2 2 2 0 cAMP-dependent protein kinase inhibitor DUF1664 PF07889.7 AJZ75841.1 - 1.1 9.1 6.9 1.9 8.2 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2203 PF09969.4 AJZ75841.1 - 1.2 9.3 4.8 2.4 8.3 1.9 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4404 PF14357.1 AJZ75841.1 - 1.5 9.3 5.9 2 8.9 2.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Sox_N PF12444.3 AJZ75841.1 - 1.6 9.9 7.5 7.7 7.7 5.2 2.0 1 1 0 1 1 1 0 Sox developmental protein N terminal Prefoldin_2 PF01920.15 AJZ75841.1 - 1.6 8.5 8.2 0.75 9.5 0.4 2.7 1 1 1 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.6 AJZ75841.1 - 1.7 9.0 7.0 0.88 10.0 1.4 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal LUC7 PF03194.10 AJZ75841.1 - 1.8 8.0 6.1 2.1 7.8 4.2 1.1 1 0 0 1 1 1 0 LUC7 N_terminus LMBR1 PF04791.11 AJZ75841.1 - 2.9 6.3 6.4 3.8 5.9 4.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YtxH PF12732.2 AJZ75841.1 - 3.1 8.2 9.1 2.7e+02 2.0 6.3 2.2 1 1 0 1 1 1 0 YtxH-like protein HSCB_C PF07743.8 AJZ75841.1 - 4 7.9 7.2 5.6 7.4 1.8 2.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain NAC PF01849.13 AJZ75842.1 - 4.2e-15 55.0 2.3 2.9e-14 52.3 1.2 2.0 2 0 0 2 2 2 1 NAC domain PhnI PF05861.7 AJZ75842.1 - 0.051 12.0 0.0 0.06 11.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) UBA_4 PF14555.1 AJZ75842.1 - 0.062 12.8 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain FdtA PF05523.6 AJZ75842.1 - 0.063 12.7 0.2 0.1 12.1 0.1 1.3 1 1 0 1 1 1 0 WxcM-like, C-terminal UBA PF00627.26 AJZ75842.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain PhoU PF01895.14 AJZ75843.1 - 1.1e-26 93.0 19.0 1.9e-19 69.8 1.7 3.0 3 0 0 3 3 3 2 PhoU domain Antitoxin-MazE PF04014.13 AJZ75843.1 - 6.8e-10 38.4 0.1 1.2e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 Antidote-toxin recognition MazE DltD_M PF04918.7 AJZ75843.1 - 0.0052 16.9 1.9 0.0071 16.5 0.6 1.7 2 0 0 2 2 2 1 DltD central region DUF3610 PF12272.3 AJZ75843.1 - 0.073 12.7 1.7 8.1 6.0 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3610) Translin PF01997.11 AJZ75843.1 - 0.15 11.6 3.7 0.34 10.4 2.6 1.6 1 0 0 1 1 1 0 Translin family MMR_HSR1 PF01926.18 AJZ75844.1 - 3e-16 59.4 0.1 5.3e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.1 AJZ75844.1 - 2e-12 47.0 0.7 6e-12 45.5 0.2 2.1 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal FeoB_N PF02421.13 AJZ75844.1 - 7e-06 25.4 0.1 1.5e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 AJZ75844.1 - 9.5e-06 25.1 2.0 0.00072 19.0 0.1 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AJZ75844.1 - 0.00029 20.0 0.1 0.00056 19.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 AJZ75844.1 - 0.0063 16.0 1.5 0.029 13.8 0.9 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 AJZ75844.1 - 0.0077 16.7 0.7 0.044 14.2 0.1 2.6 3 0 0 3 3 3 1 Miro-like protein ABC_tran PF00005.22 AJZ75844.1 - 0.0093 16.2 0.1 0.036 14.3 0.0 2.1 3 1 0 3 3 3 1 ABC transporter IDO PF01231.13 AJZ75844.1 - 0.01 14.3 0.0 0.021 13.2 0.0 1.6 1 1 1 2 2 2 0 Indoleamine 2,3-dioxygenase AsnC_trans_reg PF01037.16 AJZ75846.1 - 4.7e-09 35.8 0.0 5.5e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 AsnC family GYD PF08734.6 AJZ75846.1 - 0.00018 21.1 0.0 0.0002 20.9 0.0 1.1 1 0 0 1 1 1 1 GYD domain RibD_C PF01872.12 AJZ75847.1 - 2.5e-51 174.1 0.3 2.8e-51 173.9 0.2 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Sep15_SelM PF08806.6 AJZ75847.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Sep15/SelM redox domain Amidohydro_1 PF01979.15 AJZ75848.1 - 1.4e-28 100.5 0.9 1.8e-28 100.1 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 AJZ75848.1 - 1.3e-13 51.6 0.0 2.3e-05 24.5 0.0 2.5 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 AJZ75848.1 - 2e-09 37.1 0.0 6.4e-09 35.5 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 AJZ75848.1 - 4.6e-09 35.9 0.6 3.4e-06 26.5 0.0 2.7 1 1 1 2 2 2 2 Amidohydrolase family GGDN PF05165.7 AJZ75849.1 - 1.8e-51 174.5 0.0 2.3e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 GGDN family Guanylate_cyc PF00211.15 AJZ75849.1 - 0.00039 19.8 0.1 0.00076 18.8 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DMRL_synthase PF00885.14 AJZ75850.1 - 2.4e-32 111.5 0.4 2.6e-32 111.4 0.2 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase TOBE PF03459.12 AJZ75850.1 - 0.042 13.9 0.1 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 TOBE domain DUF3356 PF11836.3 AJZ75850.1 - 0.044 13.5 0.0 4.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3356) DHBP_synthase PF00926.14 AJZ75851.1 - 5.9e-67 224.6 0.0 6.6e-67 224.4 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Nitroreductase PF00881.19 AJZ75852.1 - 5.8e-37 127.0 0.8 9.3e-37 126.3 0.6 1.3 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.1 AJZ75852.1 - 0.0077 15.4 0.3 1 8.5 0.0 2.3 1 1 1 2 2 2 2 Putative TM nitroreductase MerC PF03203.9 AJZ75853.1 - 0.0065 16.8 0.7 0.0096 16.2 0.5 1.3 1 1 0 1 1 1 1 MerC mercury resistance protein DUF3290 PF11694.3 AJZ75853.1 - 0.011 15.5 2.5 0.012 15.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) 7TMR-DISM_7TM PF07695.6 AJZ75853.1 - 0.096 12.3 4.5 0.12 12.0 3.1 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF4383 PF14325.1 AJZ75853.1 - 0.14 12.2 1.4 0.18 11.8 1.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) DUF3366 PF11846.3 AJZ75853.1 - 0.15 11.9 0.2 0.19 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) ABC2_membrane_5 PF13346.1 AJZ75853.1 - 0.18 11.0 6.4 0.23 10.7 4.4 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2892 PF11127.3 AJZ75853.1 - 0.19 11.5 2.0 0.62 9.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF981 PF06168.6 AJZ75853.1 - 0.22 11.2 3.9 0.76 9.5 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF981) ECF-ribofla_trS PF07155.7 AJZ75853.1 - 0.28 10.8 3.8 0.32 10.7 2.6 1.1 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component CbiQ PF02361.11 AJZ75853.1 - 0.44 10.0 3.9 0.52 9.8 2.7 1.1 1 0 0 1 1 1 0 Cobalt transport protein DUF204 PF02659.10 AJZ75853.1 - 0.61 10.2 3.1 0.71 10.0 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF DUF983 PF06170.7 AJZ75853.1 - 0.66 10.1 3.4 0.28 11.3 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF983) O-antigen_lig PF13425.1 AJZ75853.1 - 0.83 9.6 4.1 0.27 11.1 1.0 1.4 1 1 0 1 1 1 0 O-antigen ligase like membrane protein DUF4064 PF13273.1 AJZ75853.1 - 6.4 6.9 7.7 1.5 9.0 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) TisB_toxin PF13939.1 AJZ75853.1 - 7.9 6.3 11.0 0.78 9.5 3.1 2.3 2 0 0 2 2 2 0 Toxin TisB, type I toxin-antitoxin system HTH_20 PF12840.2 AJZ75854.1 - 1.1e-10 41.1 0.0 1.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.5 AJZ75854.1 - 1.1e-06 28.1 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.14 AJZ75854.1 - 2.6e-06 27.0 0.3 3.9e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 AJZ75854.1 - 1.3e-05 24.7 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 AJZ75854.1 - 1.5e-05 24.2 0.7 3.4e-05 23.1 0.5 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 AJZ75854.1 - 1.6e-05 24.4 1.1 2.2e-05 23.9 0.8 1.3 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.2 AJZ75854.1 - 0.0029 17.2 0.1 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.17 AJZ75854.1 - 0.0084 15.7 0.4 0.016 14.8 0.3 1.4 1 0 0 1 1 1 1 MarR family FUR PF01475.14 AJZ75854.1 - 0.013 15.4 0.2 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_34 PF13601.1 AJZ75854.1 - 0.014 15.4 0.2 0.048 13.7 0.1 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_45 PF14947.1 AJZ75854.1 - 0.078 12.8 1.9 0.11 12.3 1.3 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix Rrf2 PF02082.15 AJZ75854.1 - 0.095 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator Mga PF05043.8 AJZ75854.1 - 0.11 12.7 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Mga helix-turn-helix domain fn3 PF00041.16 AJZ75855.1 - 2.3e-10 40.4 0.9 4e-10 39.6 0.6 1.4 1 0 0 1 1 1 1 Fibronectin type III domain TMP_2 PF06791.8 AJZ75855.1 - 0.034 13.7 5.4 0.05 13.2 0.3 2.2 1 1 1 2 2 2 0 Prophage tail length tape measure protein DUF3348 PF11828.3 AJZ75855.1 - 0.32 10.3 4.8 0.22 10.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3348) MADF_DNA_bdg PF10545.4 AJZ75855.1 - 0.44 10.7 16.3 2.1 8.6 3.4 2.9 1 1 2 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like NRN1 PF15056.1 AJZ75855.1 - 0.66 9.9 3.1 15 5.5 0.1 2.5 1 1 0 2 2 2 0 Neuritin protein family DUF1974 PF09317.6 AJZ75855.1 - 1 8.7 9.2 0.22 10.8 3.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1974) DUF883 PF05957.8 AJZ75855.1 - 1.2 9.5 12.0 7.6 7.0 2.0 3.2 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2317 PF10079.4 AJZ75855.1 - 2.4 6.6 17.6 0.95 7.9 1.5 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) Myb_DNA-bind_4 PF13837.1 AJZ75855.1 - 3.4 7.8 18.8 2.6 8.2 4.3 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DPM3 PF08285.6 AJZ75855.1 - 4.3 7.2 7.9 5.3 6.9 0.5 2.7 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) TarH PF02203.10 AJZ75855.1 - 9.1 6.0 8.0 24 4.7 2.2 3.1 1 1 1 2 2 2 0 Tar ligand binding domain homologue HTH_45 PF14947.1 AJZ75856.1 - 0.00063 19.5 3.2 0.0026 17.5 0.1 2.9 3 0 0 3 3 3 1 Winged helix-turn-helix HTH_24 PF13412.1 AJZ75856.1 - 0.0038 16.5 0.3 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 AJZ75856.1 - 0.0046 16.7 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4423 PF14394.1 AJZ75856.1 - 0.0062 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_5 PF01022.15 AJZ75856.1 - 0.019 14.5 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 AJZ75856.1 - 0.072 12.7 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 MarR family DUF2250 PF10007.4 AJZ75856.1 - 0.13 12.2 4.8 10 6.1 0.1 3.4 3 1 1 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2250) B12-binding_2 PF02607.12 AJZ75857.1 - 6.2e-13 48.5 0.0 9.4e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.14 AJZ75857.1 - 3.7e-12 46.1 0.0 5.4e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain OKR_DC_1_N PF03709.10 AJZ75857.1 - 0.0058 16.6 0.1 0.034 14.2 0.0 2.2 3 0 0 3 3 3 1 Orn/Lys/Arg decarboxylase, N-terminal domain FAD_binding_7 PF03441.9 AJZ75858.1 - 8.8e-89 297.3 2.2 1.4e-88 296.7 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 AJZ75858.1 - 2.4e-39 134.7 0.3 1e-38 132.6 0.0 2.0 2 0 0 2 2 2 1 DNA photolyase Nitroreductase PF00881.19 AJZ75859.1 - 3.5e-28 98.4 0.1 5.8e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Nitroreductase family DUF1411 PF07199.6 AJZ75859.1 - 0.15 11.5 2.3 0.12 11.7 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1411) zf-ribbon_3 PF13248.1 AJZ75861.1 - 0.002 17.2 3.4 0.0029 16.7 2.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain Cys_rich_KTR PF14205.1 AJZ75861.1 - 0.013 14.9 0.5 0.024 14.0 0.3 1.5 1 0 0 1 1 1 0 Cysteine-rich KTR zf-IS66 PF13005.2 AJZ75861.1 - 0.039 13.9 3.2 0.2 11.6 0.3 2.4 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Toxin_28 PF08115.6 AJZ75861.1 - 0.048 13.3 0.3 0.048 13.3 0.2 1.6 2 0 0 2 2 2 0 SFI toxin family DZR PF12773.2 AJZ75861.1 - 0.088 12.6 5.4 0.071 12.9 3.2 1.4 1 1 0 1 1 1 0 Double zinc ribbon HIPIP PF01355.12 AJZ75861.1 - 0.088 12.9 3.9 0.11 12.6 2.7 1.2 1 0 0 1 1 1 0 High potential iron-sulfur protein zf-FCS PF06467.9 AJZ75861.1 - 0.37 10.4 0.3 0.37 10.4 0.2 2.6 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Prim_Zn_Ribbon PF08273.7 AJZ75861.1 - 0.4 10.7 6.2 0.69 10.0 0.8 2.3 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Prok-RING_1 PF14446.1 AJZ75861.1 - 0.73 9.6 5.9 0.12 12.0 1.5 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.1 AJZ75861.1 - 3.3 7.4 8.2 5.3 6.7 5.7 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.2 AJZ75861.1 - 5.2 6.9 8.3 5.6 6.8 1.8 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DNA_RNApol_7kD PF03604.8 AJZ75861.1 - 6 6.4 7.8 1.2e+02 2.2 5.4 2.3 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-HYPF PF07503.7 AJZ75861.1 - 7.2 6.1 10.4 0.19 11.1 0.8 2.6 1 1 1 2 2 2 0 HypF finger Methyltransf_11 PF08241.7 AJZ75863.1 - 2.5e-12 47.1 0.0 6.1e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJZ75863.1 - 1.1e-09 38.1 0.0 1.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJZ75863.1 - 2.7e-06 27.7 0.0 6.5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJZ75863.1 - 1.3e-05 24.8 0.0 5e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 AJZ75863.1 - 2.6e-05 23.6 0.0 6.5e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 AJZ75863.1 - 9.1e-05 21.6 0.0 0.00025 20.2 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 AJZ75863.1 - 0.0008 19.7 0.0 0.0022 18.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain BphX PF06139.7 AJZ75864.1 - 0.0094 15.5 1.7 0.13 11.8 0.0 3.1 3 0 0 3 3 3 1 BphX-like DUF4239 PF14023.1 AJZ75864.1 - 0.1 11.9 0.2 2.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DUF4526 PF15029.1 AJZ75864.1 - 0.11 12.0 0.9 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4526) DUF11 PF01345.13 AJZ75865.1 - 0.013 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF11 CARDB PF07705.6 AJZ75865.1 - 0.12 12.4 0.1 0.39 10.7 0.1 1.8 1 1 0 1 1 1 0 CARDB BT1 PF03092.11 AJZ75865.1 - 0.14 10.8 0.1 0.2 10.3 0.1 1.2 1 0 0 1 1 1 0 BT1 family HpcH_HpaI PF03328.9 AJZ75866.1 - 1.1e-46 158.4 0.0 1.3e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 AJZ75866.1 - 3.6e-17 62.2 0.0 2.1e-08 33.3 0.0 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Trehalose_PPase PF02358.11 AJZ75866.1 - 0.0037 16.2 0.0 0.0068 15.3 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase ADH_zinc_N PF00107.21 AJZ75867.1 - 3.9e-30 104.0 0.1 7e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AJZ75867.1 - 2.5e-24 85.1 0.3 4.3e-24 84.3 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AJZ75867.1 - 3.2e-16 60.3 0.0 9.8e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.5 AJZ75867.1 - 0.069 13.1 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal dsDNA_bind PF01984.15 AJZ75868.1 - 1.1e-24 86.4 0.4 1.2e-24 86.3 0.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Ribosomal_S19e PF01090.14 AJZ75869.1 - 1.5e-48 163.7 0.0 1.7e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e GntR PF00392.16 AJZ75869.1 - 0.052 12.9 0.1 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_11 PF08279.7 AJZ75869.1 - 0.11 12.2 0.2 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 HTH domain Rpr2 PF04032.11 AJZ75870.1 - 6.6e-17 61.1 0.9 7.7e-17 60.9 0.6 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain C1_1 PF00130.17 AJZ75870.1 - 0.022 14.4 0.3 0.035 13.8 0.2 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sigma54_DBD PF04552.8 AJZ75870.1 - 0.059 12.8 0.1 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Sigma-54, DNA binding domain DUF572 PF04502.8 AJZ75870.1 - 0.077 12.2 1.1 0.091 11.9 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF951 PF06107.6 AJZ75870.1 - 0.14 11.7 1.1 8.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) DZR PF12773.2 AJZ75870.1 - 0.21 11.4 1.3 0.4 10.5 0.9 1.5 1 1 0 1 1 1 0 Double zinc ribbon RNA_POL_M_15KD PF02150.11 AJZ75870.1 - 0.51 10.0 3.0 0.93 9.2 0.4 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Sua5_yciO_yrdC PF01300.13 AJZ75871.1 - 6.3e-59 198.2 0.1 9.4e-59 197.6 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 AJZ75871.1 - 6.9e-31 106.9 0.0 1.1e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding HTH_AsnC-type PF13404.1 AJZ75872.1 - 1.2e-13 50.3 0.2 1.7e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 AJZ75872.1 - 1.9e-11 43.1 0.3 3e-11 42.5 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.14 AJZ75872.1 - 2.5e-05 23.8 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 AJZ75872.1 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DUF2250 PF10007.4 AJZ75872.1 - 0.00014 21.6 0.4 0.0033 17.3 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) Arc_trans_TRASH PF08394.5 AJZ75872.1 - 0.00045 20.3 3.2 0.00074 19.6 2.2 1.4 1 0 0 1 1 1 1 Archaeal TRASH domain ATPase-cat_bd PF12156.3 AJZ75872.1 - 0.0011 19.4 0.7 0.0034 17.8 0.4 1.8 2 0 0 2 2 2 1 Putative metal-binding domain of cation transport ATPase HTH_9 PF08221.6 AJZ75872.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 AJZ75872.1 - 0.0052 15.9 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 zf-FCS PF06467.9 AJZ75872.1 - 0.011 15.3 1.1 0.025 14.2 0.8 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif HTH_28 PF13518.1 AJZ75872.1 - 0.011 15.6 0.1 0.031 14.3 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain FeoC PF09012.5 AJZ75872.1 - 0.012 15.3 0.0 0.012 15.3 0.0 2.5 3 1 1 4 4 4 0 FeoC like transcriptional regulator DUF1272 PF06906.6 AJZ75872.1 - 0.023 14.5 1.1 0.037 13.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) MarR_2 PF12802.2 AJZ75872.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.1 AJZ75872.1 - 0.031 13.9 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain DUF4423 PF14394.1 AJZ75872.1 - 0.036 13.6 0.1 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_20 PF12840.2 AJZ75872.1 - 0.042 13.6 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 AJZ75872.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2089 PF09862.4 AJZ75872.1 - 0.098 12.4 0.1 0.23 11.2 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2089) Fe_dep_repress PF01325.14 AJZ75872.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Ribosomal_L44 PF00935.14 AJZ75872.1 - 4.2 7.4 6.2 0.48 10.4 0.3 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 Ferritin PF00210.19 AJZ75873.1 - 2.5e-30 105.0 0.4 2.8e-30 104.9 0.3 1.0 1 0 0 1 1 1 1 Ferritin-like domain Osmo_CC PF08946.5 AJZ75873.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF2383 PF09537.5 AJZ75873.1 - 0.096 12.9 0.1 13 6.0 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF2383) Cation_efflux PF01545.16 AJZ75874.1 - 2.2e-69 233.6 14.3 2.4e-69 233.5 9.9 1.0 1 0 0 1 1 1 1 Cation efflux family HTH_5 PF01022.15 AJZ75876.1 - 1.3e-15 56.8 0.1 4.2e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 AJZ75876.1 - 4.9e-08 32.2 0.1 0.0061 15.9 0.0 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding TrmB PF01978.14 AJZ75876.1 - 1.7e-07 30.8 0.0 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 AJZ75876.1 - 2.6e-06 27.0 0.2 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 2 MarR family HTH_34 PF13601.1 AJZ75876.1 - 5.7e-05 23.0 0.5 0.12 12.4 0.1 2.3 2 0 0 2 2 2 2 Winged helix DNA-binding domain MarR_2 PF12802.2 AJZ75876.1 - 0.00038 20.0 0.0 0.0061 16.1 0.0 2.1 2 0 0 2 2 2 1 MarR family HTH_45 PF14947.1 AJZ75876.1 - 0.00052 19.7 1.3 0.0029 17.3 0.1 2.2 2 1 0 2 2 2 1 Winged helix-turn-helix Rrf2 PF02082.15 AJZ75876.1 - 0.0019 18.3 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 2 Transcriptional regulator HTH_20 PF12840.2 AJZ75876.1 - 0.003 17.3 0.0 0.86 9.4 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_IclR PF09339.5 AJZ75876.1 - 0.01 15.3 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain FeoC PF09012.5 AJZ75876.1 - 0.049 13.3 0.3 3.8 7.2 0.0 2.2 2 0 0 2 2 2 0 FeoC like transcriptional regulator Filamin PF00630.14 AJZ75880.1 - 0.11 13.0 0.4 0.23 12.0 0.3 1.7 1 1 0 1 1 1 0 Filamin/ABP280 repeat DUF1272 PF06906.6 AJZ75881.1 - 0.077 12.8 8.8 0.47 10.3 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) MSSP PF03940.8 AJZ75881.1 - 0.41 10.0 7.8 0.58 9.6 5.4 1.2 1 0 0 1 1 1 0 Male specific sperm protein NOB1_Zn_bind PF08772.6 AJZ75881.1 - 3.2 7.6 12.2 0.24 11.2 4.1 1.9 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_3 PF14369.1 AJZ75881.1 - 8.4 6.4 10.0 3.1 7.8 0.8 3.0 1 1 2 3 3 3 0 zinc-finger HTH_24 PF13412.1 AJZ75883.1 - 5e-18 64.2 4.4 4.1e-08 32.4 0.1 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AJZ75883.1 - 8.1e-12 44.6 0.0 1.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 MarR family HTH_20 PF12840.2 AJZ75883.1 - 1.6e-11 43.8 0.0 1.9e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_5 PF01022.15 AJZ75883.1 - 4.8e-10 38.9 0.1 0.00018 21.1 0.1 2.4 2 1 0 2 2 2 2 Bacterial regulatory protein, arsR family MarR PF01047.17 AJZ75883.1 - 4.1e-09 35.9 0.3 0.0018 17.8 0.1 2.2 2 0 0 2 2 2 2 MarR family FaeA PF04703.7 AJZ75883.1 - 1.1e-07 31.8 0.0 0.0056 16.8 0.0 2.4 2 0 0 2 2 2 2 FaeA-like protein HTH_34 PF13601.1 AJZ75883.1 - 3.5e-07 30.1 0.0 4.6e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.14 AJZ75883.1 - 1.8e-06 27.5 0.0 0.0099 15.5 0.0 2.2 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.1 AJZ75883.1 - 2e-05 24.2 0.0 0.013 15.0 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4423) HTH_IclR PF09339.5 AJZ75883.1 - 2e-05 24.0 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_27 PF13463.1 AJZ75883.1 - 0.00028 21.1 0.0 0.18 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_11 PF08279.7 AJZ75883.1 - 0.00045 19.8 0.1 0.021 14.4 0.0 2.6 2 1 1 3 3 3 1 HTH domain GerE PF00196.14 AJZ75883.1 - 0.00068 18.8 0.1 0.11 11.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family EAP30 PF04157.11 AJZ75883.1 - 0.001 18.2 0.0 0.0079 15.3 0.0 1.9 2 0 0 2 2 2 1 EAP30/Vps36 family DUF2250 PF10007.4 AJZ75883.1 - 0.001 18.9 0.4 0.31 10.9 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) FeoC PF09012.5 AJZ75883.1 - 0.0014 18.2 0.0 0.0083 15.8 0.0 1.9 2 0 0 2 2 2 1 FeoC like transcriptional regulator HTH_45 PF14947.1 AJZ75883.1 - 0.0017 18.1 0.7 0.38 10.6 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix RPA_C PF08784.6 AJZ75883.1 - 0.0024 18.2 0.8 0.0047 17.3 0.1 1.8 2 1 0 2 2 2 1 Replication protein A C terminal LexA_DNA_bind PF01726.11 AJZ75883.1 - 0.0031 17.0 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 1 LexA DNA binding domain B-block_TFIIIC PF04182.7 AJZ75883.1 - 0.0044 16.8 0.1 0.39 10.6 0.1 2.3 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC z-alpha PF02295.12 AJZ75883.1 - 0.0075 16.0 1.6 0.64 9.8 0.2 2.5 2 1 1 3 3 3 1 Adenosine deaminase z-alpha domain HTH_36 PF13730.1 AJZ75883.1 - 0.029 14.4 0.0 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Mga PF05043.8 AJZ75883.1 - 0.032 14.5 0.3 5 7.4 0.0 2.6 2 1 0 2 2 2 0 Mga helix-turn-helix domain Penicillinase_R PF03965.11 AJZ75883.1 - 0.039 14.0 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Penicillinase repressor GntR PF00392.16 AJZ75883.1 - 0.074 12.4 0.0 9.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.7 AJZ75883.1 - 0.086 12.3 0.6 0.21 11.1 0.0 2.0 3 0 0 3 3 2 0 DeoR-like helix-turn-helix domain DUF4496 PF14908.1 AJZ75884.1 - 0.11 12.3 0.7 0.13 12.1 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4496) DUF4199 PF13858.1 AJZ75884.1 - 0.14 12.0 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) MFMR PF07777.6 AJZ75884.1 - 0.27 11.1 3.4 0.3 10.9 2.3 1.0 1 0 0 1 1 1 0 G-box binding protein MFMR Usp PF00582.21 AJZ75885.1 - 7.7e-32 110.3 0.0 8.6e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family DNA_photolyase PF00875.13 AJZ75885.1 - 0.0058 16.3 0.0 0.0081 15.9 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase L-fibroin PF05849.6 AJZ75885.1 - 0.043 13.1 0.9 0.066 12.5 0.6 1.3 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) DUF1628 PF07790.6 AJZ75886.1 - 0.06 14.1 0.8 0.086 13.6 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) MFS_1 PF07690.11 AJZ75887.1 - 3.6e-38 131.1 30.1 4.2e-24 84.9 6.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AJZ75887.1 - 2.5e-08 32.7 22.7 0.0003 19.3 8.1 2.8 2 1 1 3 3 3 3 MFS/sugar transport protein LacY_symp PF01306.14 AJZ75887.1 - 1.6e-06 26.9 2.6 1.6e-06 26.9 1.8 2.4 2 1 0 2 2 2 1 LacY proton/sugar symporter ATG22 PF11700.3 AJZ75887.1 - 3.3e-05 22.5 25.1 0.0036 15.8 9.1 2.8 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_3 PF05977.8 AJZ75887.1 - 0.00048 18.3 6.4 0.0013 16.9 4.4 1.8 1 1 0 1 1 1 1 Transmembrane secretion effector FPN1 PF06963.7 AJZ75887.1 - 0.066 11.5 6.2 1.6 7.0 0.1 2.6 2 1 1 3 3 3 0 Ferroportin1 (FPN1) NMN_transporter PF04973.7 AJZ75887.1 - 2.4 7.5 10.5 0.7 9.3 0.4 2.9 3 0 0 3 3 3 0 Nicotinamide mononucleotide transporter SWM_repeat PF13753.1 AJZ75888.1 - 0.17 10.9 4.5 0.28 10.1 3.1 1.5 1 1 0 1 1 1 0 Putative flagellar system-associated repeat EamA PF00892.15 AJZ75889.1 - 1.3e-35 122.1 34.2 4.4e-18 65.5 8.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 AJZ75889.1 - 2.3e-11 43.9 28.9 3e-06 27.4 5.1 3.2 2 2 2 4 4 4 3 Multidrug resistance efflux transporter UPF0546 PF10639.4 AJZ75889.1 - 0.00025 20.8 14.8 0.0029 17.4 1.3 2.8 2 1 0 2 2 2 2 Uncharacterised protein family UPF0546 TPT PF03151.11 AJZ75889.1 - 0.1 12.2 30.8 0.2 11.2 7.8 3.0 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF4536 PF15055.1 AJZ75889.1 - 0.2 11.7 1.6 0.44 10.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Multi_Drug_Res PF00893.14 AJZ75889.1 - 0.71 10.3 17.8 0.1 13.0 2.2 3.2 2 2 0 2 2 2 0 Small Multidrug Resistance protein EMG1 PF03587.9 AJZ75890.1 - 4.2e-45 153.5 0.0 4.7e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyco_hydro_42 PF02449.10 AJZ75891.1 - 0.0014 17.8 0.4 0.013 14.6 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 AJZ75891.1 - 0.0071 15.7 1.0 0.011 15.1 0.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 ApoLp-III PF07464.6 AJZ75891.1 - 0.048 13.6 0.0 0.55 10.2 0.0 2.6 1 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) EF1G PF00647.14 AJZ75891.1 - 0.067 12.9 0.1 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain Ribonuc_red_lgC PF02867.10 AJZ75892.1 - 5.3e-154 513.7 0.0 9.6e-154 512.8 0.0 1.4 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 AJZ75892.1 - 1.4e-29 101.6 0.2 3.4e-29 100.4 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 AJZ75892.1 - 4.9e-23 81.3 0.1 1.5e-22 79.8 0.1 1.9 1 0 0 1 1 1 1 ATP cone domain DUF35 PF01796.12 AJZ75893.1 - 1.1e-09 38.3 0.1 1.6e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain zinc_ribbon_2 PF13240.1 AJZ75893.1 - 0.0011 18.4 3.6 0.0018 17.7 2.5 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DUF35_N PF12172.3 AJZ75893.1 - 0.0073 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.2 AJZ75893.1 - 0.018 14.8 0.4 0.026 14.3 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon GFA PF04828.9 AJZ75893.1 - 0.027 14.4 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 AJZ75893.1 - 0.071 12.9 0.9 0.098 12.4 0.6 1.2 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Thioredoxin_3 PF13192.1 AJZ75893.1 - 0.086 12.6 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin domain zinc_ribbon_5 PF13719.1 AJZ75893.1 - 0.089 12.3 1.5 5 6.7 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AJZ75893.1 - 0.12 12.0 1.6 4.9 6.9 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AJZ75893.1 - 0.29 10.4 4.9 1.3 8.2 3.4 1.9 1 1 0 1 1 1 0 zinc-ribbon domain DUF1610 PF07754.6 AJZ75893.1 - 2 8.5 6.0 2.1 8.5 1.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1610) Thiolase_C PF02803.13 AJZ75894.1 - 2.9e-12 46.0 2.5 1.5e-10 40.5 0.1 3.4 2 2 1 3 3 3 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 AJZ75894.1 - 7e-07 28.4 0.1 9.7e-06 24.7 0.0 2.3 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 AJZ75894.1 - 0.00056 19.4 0.1 0.044 13.2 0.1 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 AJZ75894.1 - 0.0017 17.9 0.1 0.75 9.4 0.1 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.17 AJZ75894.1 - 0.06 13.1 1.1 0.68 9.8 0.0 2.8 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain zf-C4_Topoisom PF01396.14 AJZ75895.1 - 1.1e-06 27.9 11.0 3e-06 26.6 1.7 2.6 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_recom PF13408.1 AJZ75895.1 - 0.009 16.2 3.1 0.009 16.2 2.1 2.4 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Ribosomal_L29 PF00831.18 AJZ75895.1 - 0.067 12.8 2.6 0.1 12.2 1.8 1.3 1 0 0 1 1 1 0 Ribosomal L29 protein Auto_anti-p27 PF06677.7 AJZ75895.1 - 0.27 11.0 1.7 0.83 9.4 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2810 PF10928.3 AJZ75895.1 - 0.51 10.1 2.5 4.3 7.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2810) Zn_Tnp_IS1595 PF12760.2 AJZ75895.1 - 2.5 7.9 8.4 0.71 9.7 0.5 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Ogr_Delta PF04606.7 AJZ75895.1 - 7 6.4 10.2 8.9 6.0 1.2 3.2 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger CN_hydrolase PF00795.17 AJZ75896.1 - 5e-33 114.0 0.0 6.7e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PcfK PF14058.1 AJZ75896.1 - 0.16 12.1 2.2 0.33 11.0 1.5 1.5 1 1 0 1 1 1 0 PcfK-like protein Tautomerase PF01361.16 AJZ75897.1 - 3e-15 55.5 0.0 3.2e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.1 AJZ75897.1 - 2e-09 37.3 0.0 2.1e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_3 PF14832.1 AJZ75897.1 - 0.035 14.0 0.0 0.036 14.0 0.0 1.0 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme Matrix PF00661.16 AJZ75897.1 - 0.041 12.2 0.0 0.041 12.2 0.0 1.0 1 0 0 1 1 1 0 Viral matrix protein Rhomboid PF01694.17 AJZ75898.1 - 1.3e-31 109.5 21.0 1.3e-31 109.5 14.5 1.5 2 0 0 2 2 2 1 Rhomboid family DUF3987 PF13148.1 AJZ75899.1 - 0.018 13.5 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Dioxygenase_N PF04444.9 AJZ75899.1 - 0.032 14.2 0.1 8 6.5 0.0 2.4 2 0 0 2 2 2 0 Catechol dioxygenase N terminus Copper-bind PF00127.15 AJZ75901.1 - 7.6e-06 26.0 0.5 2.4e-05 24.4 0.0 2.0 2 1 1 3 3 3 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJZ75901.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.8 2 0 0 2 2 2 0 Cupredoxin-like domain DUF824 PF05688.6 AJZ75901.1 - 0.053 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Big_1 PF02369.11 AJZ75901.1 - 0.075 12.9 2.0 0.14 12.1 0.3 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) YtkA PF13115.1 AJZ75901.1 - 0.1 12.9 0.4 0.24 11.7 0.2 1.7 1 0 0 1 1 1 0 YtkA-like Rotamase_2 PF13145.1 AJZ75902.1 - 0.045 14.3 0.2 0.18 12.4 0.0 1.9 1 1 1 2 2 2 0 PPIC-type PPIASE domain CopD PF05425.8 AJZ75903.1 - 1e-14 54.5 2.0 1e-14 54.5 1.4 2.9 2 1 0 2 2 2 1 Copper resistance protein D CopC PF04234.7 AJZ75903.1 - 1.4e-13 51.2 0.0 4.8e-13 49.5 0.0 2.0 1 0 0 1 1 1 1 CopC domain SGL PF08450.7 AJZ75903.1 - 1.3e-10 41.0 0.1 0.0003 20.2 0.0 4.8 1 1 4 5 5 5 4 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 AJZ75903.1 - 2.5e-08 32.9 7.0 1.6 8.9 0.0 7.8 9 0 0 9 9 8 3 Two component regulator propeller YtkA PF13115.1 AJZ75903.1 - 2.3e-05 24.6 0.0 9.9e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 YtkA-like Y_Y_Y PF07495.8 AJZ75903.1 - 0.015 15.0 3.7 0.026 14.2 0.0 3.0 3 0 0 3 3 3 0 Y_Y_Y domain FBA_3 PF08268.7 AJZ75903.1 - 0.019 14.7 0.1 5.2 6.8 0.0 3.0 2 1 1 3 3 3 0 F-box associated domain Big_3_4 PF13754.1 AJZ75903.1 - 0.028 14.7 1.2 14 6.0 0.1 3.5 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) FlgD_ig PF13860.1 AJZ75903.1 - 0.1 12.3 0.8 8.3 6.2 0.2 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain PPC PF04151.10 AJZ75903.1 - 0.14 13.1 5.3 0.13 13.2 1.3 2.6 3 0 0 3 3 2 0 Bacterial pre-peptidase C-terminal domain DUF4149 PF13664.1 AJZ75903.1 - 0.91 9.6 18.5 0.09 12.8 1.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) DUF3112 PF11309.3 AJZ75903.1 - 1.9 8.2 9.0 2.3 7.9 5.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Myosin_tail_1 PF01576.14 AJZ75904.1 - 0.00021 19.2 71.4 0.039 11.6 17.6 4.2 2 1 1 3 3 3 3 Myosin tail TBPIP PF07106.8 AJZ75904.1 - 0.00043 19.8 75.5 0.13 11.7 1.5 5.7 3 1 3 6 6 6 4 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 AJZ75904.1 - 0.00075 19.1 90.5 0.0036 16.9 15.8 5.1 2 1 3 5 5 5 2 IncA protein Filament PF00038.16 AJZ75904.1 - 0.0012 18.3 70.6 0.049 13.0 15.9 3.9 1 1 3 4 4 4 3 Intermediate filament protein Reo_sigmaC PF04582.7 AJZ75904.1 - 0.0097 15.1 25.8 1.4 8.0 0.9 4.9 2 2 3 5 5 5 4 Reovirus sigma C capsid protein EAP30 PF04157.11 AJZ75904.1 - 0.011 14.8 4.2 0.011 14.8 2.9 5.3 3 1 1 5 5 4 0 EAP30/Vps36 family Tropomyosin_1 PF12718.2 AJZ75904.1 - 0.012 15.4 19.4 0.012 15.4 13.5 5.8 3 2 3 6 6 6 0 Tropomyosin like Seryl_tRNA_N PF02403.17 AJZ75904.1 - 0.02 14.9 12.5 0.02 14.9 8.7 6.4 3 1 3 6 6 6 0 Seryl-tRNA synthetase N-terminal domain PspA_IM30 PF04012.7 AJZ75904.1 - 0.035 13.4 0.1 0.035 13.4 0.1 5.0 2 1 0 3 3 3 0 PspA/IM30 family DUF812 PF05667.6 AJZ75904.1 - 0.046 12.2 71.4 0.86 8.0 6.4 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF812) AAA_27 PF13514.1 AJZ75904.1 - 0.095 10.3 54.9 0.21 9.2 32.8 2.3 1 1 1 2 2 2 0 AAA domain DUF972 PF06156.8 AJZ75904.1 - 0.1 12.9 61.5 0.33 11.3 2.3 6.7 3 1 4 7 7 7 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 AJZ75904.1 - 0.18 11.9 66.1 1 9.5 5.9 7.9 3 1 6 9 9 9 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.3 AJZ75904.1 - 0.21 11.4 73.7 0.039 13.8 10.7 5.7 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 AJZ75904.1 - 0.26 11.1 44.7 0.23 11.3 5.1 6.3 3 1 4 7 7 7 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 AJZ75904.1 - 0.39 9.3 84.6 0.35 9.4 6.5 5.4 2 1 3 5 5 5 0 Spc7 kinetochore protein MAD PF05557.8 AJZ75904.1 - 0.74 7.8 75.4 0.31 9.1 15.9 3.6 1 1 2 3 3 3 0 Mitotic checkpoint protein APG6 PF04111.7 AJZ75904.1 - 1.3 8.0 79.0 0.32 10.0 1.8 4.4 2 1 2 4 4 4 0 Autophagy protein Apg6 Laminin_II PF06009.7 AJZ75904.1 - 1.3 8.7 50.6 1.3 8.8 0.4 5.8 3 1 4 7 7 7 0 Laminin Domain II DUF4164 PF13747.1 AJZ75904.1 - 1.4 9.1 56.2 0.7 10.0 3.7 6.8 2 1 5 7 7 7 0 Domain of unknown function (DUF4164) AAA_13 PF13166.1 AJZ75904.1 - 1.8 6.8 74.4 0.66 8.3 22.3 3.3 1 1 1 3 3 3 0 AAA domain CENP-F_leu_zip PF10473.4 AJZ75904.1 - 2.8 7.7 81.2 0.42 10.4 1.2 6.1 3 1 2 5 5 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 AJZ75904.1 - 3.2 7.7 44.6 1.7 8.6 3.5 8.1 3 2 3 7 7 7 0 Flagella accessory protein C (FlaC) Adeno_PIX PF03955.9 AJZ75904.1 - 3.2 8.3 30.3 2.1 8.8 0.1 6.0 3 1 3 7 7 7 0 Adenovirus hexon-associated protein (IX) DUF869 PF05911.6 AJZ75904.1 - 3.7 5.6 72.4 2.7 6.0 14.8 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) ABC_tran PF00005.22 AJZ75905.1 - 2.5e-27 95.8 0.0 6.1e-27 94.5 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 AJZ75905.1 - 1.7e-16 61.0 0.2 1.8e-14 54.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 AJZ75905.1 - 8.8e-08 31.6 1.1 0.00064 18.8 0.1 2.5 1 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 AJZ75905.1 - 2.3e-06 28.0 5.0 1.6e-05 25.3 3.4 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 AJZ75905.1 - 6.4e-05 22.2 1.4 0.012 14.8 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AJZ75905.1 - 0.0012 18.2 0.1 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 AJZ75905.1 - 0.0014 18.8 0.9 0.1 12.7 0.6 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 AJZ75905.1 - 0.0046 16.0 0.0 0.0093 15.0 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 AJZ75905.1 - 0.013 15.3 0.2 0.079 12.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AJZ75905.1 - 0.018 14.9 0.8 3.4 7.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 AJZ75905.1 - 0.024 14.3 0.9 0.083 12.5 0.5 2.0 1 1 0 1 1 1 0 Archaeal ATPase SbcCD_C PF13558.1 AJZ75905.1 - 0.036 13.9 0.0 1.4 8.9 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 AJZ75905.1 - 0.039 13.9 0.1 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 AJZ75905.1 - 0.044 14.1 0.2 0.23 11.7 0.0 2.0 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 AJZ75905.1 - 0.044 12.6 2.9 0.073 11.9 0.1 2.2 2 1 0 2 2 2 0 NB-ARC domain Septin PF00735.13 AJZ75905.1 - 0.049 12.6 1.5 12 4.7 0.0 3.0 3 0 0 3 3 3 0 Septin UPF0079 PF02367.12 AJZ75905.1 - 0.051 13.2 0.6 0.089 12.4 0.1 1.6 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 AJZ75905.1 - 0.055 13.1 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 AJZ75905.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 AJZ75905.1 - 0.081 12.8 0.8 0.19 11.6 0.5 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 AJZ75905.1 - 0.095 12.1 0.2 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 AJZ75905.1 - 0.13 12.3 0.2 0.37 10.9 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AJZ75905.1 - 0.2 12.4 0.9 0.39 11.5 0.6 1.9 1 1 0 1 1 1 0 AAA domain NikR_C PF08753.6 AJZ75906.1 - 4.4e-10 39.3 1.9 6.2e-10 38.8 1.3 1.2 1 0 0 1 1 1 1 NikR C terminal nickel binding domain RHH_1 PF01402.16 AJZ75906.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family DUF2191 PF09957.4 AJZ75906.1 - 0.00036 20.2 0.1 0.0009 19.0 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2191) CheC PF04509.7 AJZ75908.1 - 2.7e-05 23.8 0.4 6.4e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 CheC-like family CheX PF13690.1 AJZ75908.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX Response_reg PF00072.19 AJZ75909.1 - 3.9e-25 88.0 1.2 4.7e-25 87.7 0.8 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CheW PF01584.14 AJZ75910.1 - 5.6e-36 123.0 2.1 6.5e-36 122.8 1.4 1.1 1 0 0 1 1 1 1 CheW-like domain CheR PF01739.13 AJZ75911.1 - 3.7e-55 186.2 0.0 4.7e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.1 AJZ75911.1 - 1.1e-10 41.2 0.0 0.00014 21.4 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 AJZ75911.1 - 8.7e-08 32.7 0.0 1.5e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJZ75911.1 - 9.6e-06 25.4 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR_N PF03705.10 AJZ75911.1 - 1e-05 24.8 0.0 2.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.7 AJZ75911.1 - 1.1e-05 25.8 0.1 0.0001 22.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJZ75911.1 - 2e-05 24.8 0.0 3.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AJZ75911.1 - 4.6e-05 23.8 0.1 0.00076 19.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 AJZ75911.1 - 0.0066 15.6 0.0 0.0095 15.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Mnd1 PF03962.10 AJZ75912.1 - 0.0027 17.4 0.9 0.003 17.2 0.6 1.1 1 0 0 1 1 1 1 Mnd1 family Toxin_52 PF15605.1 AJZ75912.1 - 0.0052 16.6 0.4 0.0061 16.4 0.3 1.2 1 0 0 1 1 1 1 Putative toxin 52 BLOC1_2 PF10046.4 AJZ75912.1 - 0.015 15.4 0.6 0.035 14.2 0.1 1.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cobalamin_bind PF01122.14 AJZ75912.1 - 0.015 13.8 1.7 0.021 13.4 0.7 1.5 1 1 1 2 2 2 0 Eukaryotic cobalamin-binding protein DUF1730 PF08331.5 AJZ75912.1 - 0.041 13.5 0.1 0.076 12.6 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1730) Coat_F PF07875.7 AJZ75912.1 - 0.1 12.7 0.3 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 Coat F domain Exonuc_VII_S PF02609.11 AJZ75912.1 - 0.43 10.4 3.4 11 5.9 0.2 2.6 3 0 0 3 3 3 0 Exonuclease VII small subunit MACPF PF01823.14 AJZ75913.1 - 0.045 13.4 0.1 0.09 12.4 0.0 1.5 2 0 0 2 2 2 0 MAC/Perforin domain DUF3671 PF12420.3 AJZ75913.1 - 4.2 7.3 11.6 1.1 9.3 0.8 3.1 2 1 0 2 2 2 0 Protein of unknown function T2SE PF00437.15 AJZ75914.1 - 1.8e-46 158.2 0.0 2.6e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 AJZ75914.1 - 0.049 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 AJZ75914.1 - 0.051 13.0 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.22 AJZ75914.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 AJZ75915.1 - 2.2e-16 59.6 0.0 2.5e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 KaiC DUF835 PF05763.7 AJZ75915.1 - 0.00079 18.9 0.1 0.0016 18.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF835) AAA_25 PF13481.1 AJZ75915.1 - 0.0027 17.1 0.0 0.0065 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 AJZ75915.1 - 0.014 15.0 0.1 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 AJZ75915.1 - 0.022 14.7 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 AJZ75915.1 - 0.026 13.5 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 AJZ75915.1 - 0.029 13.4 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 AJZ75915.1 - 0.034 14.0 0.1 0.15 11.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 AJZ75915.1 - 0.035 13.7 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 AJZ75915.1 - 0.037 14.1 0.0 0.056 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AJZ75915.1 - 0.039 14.1 0.1 0.12 12.5 0.1 1.9 1 1 0 1 1 1 0 RNA helicase Ras PF00071.17 AJZ75915.1 - 0.058 12.7 0.1 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Ras family ATP-synt_ab PF00006.20 AJZ75915.1 - 0.068 12.6 0.0 0.097 12.1 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 AJZ75915.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain DUF2348 PF09807.4 AJZ75915.1 - 0.091 11.8 0.5 0.92 8.5 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2348) Helicase_RecD PF05127.9 AJZ75915.1 - 0.095 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Helicase AAA_24 PF13479.1 AJZ75915.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 AJZ75915.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF165 PF02592.10 AJZ75916.1 - 0.35 11.0 2.8 0.2 11.8 0.6 1.6 2 0 0 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 Arch_flagellin PF01917.11 AJZ75917.1 - 7.3e-09 35.5 6.4 1.3e-07 31.4 4.5 2.0 1 1 0 1 1 1 1 Archaebacterial flagellin SdrG_C_C PF10425.4 AJZ75917.1 - 0.048 13.6 0.2 0.085 12.8 0.1 1.4 1 1 1 2 2 2 0 C-terminus of bacterial fibrinogen-binding adhesin Ail_Lom PF06316.6 AJZ75917.1 - 0.11 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein WEMBL PF05701.6 AJZ75918.1 - 0.038 12.4 0.2 0.053 11.9 0.2 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Prefoldin_3 PF13758.1 AJZ75918.1 - 0.05 13.3 0.7 0.15 11.8 0.2 1.9 1 1 1 2 2 2 0 Prefoldin subunit Bacillus_HBL PF05791.6 AJZ75918.1 - 0.056 12.8 0.8 0.088 12.1 0.6 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) ThylakoidFormat PF11264.3 AJZ75918.1 - 0.06 12.9 0.6 0.11 12.0 0.4 1.4 1 0 0 1 1 1 0 Thylakoid formation protein DUF2730 PF10805.3 AJZ75918.1 - 0.098 12.4 0.2 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) MtrD PF04207.7 AJZ75918.1 - 0.1 11.9 0.4 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D Arch_flagellin PF01917.11 AJZ75919.1 - 1.2e-19 70.6 7.1 1.8e-19 70.1 4.9 1.3 1 0 0 1 1 1 1 Archaebacterial flagellin Arch_flagellin PF01917.11 AJZ75920.1 - 2.2e-17 63.3 13.5 5.3e-17 62.0 9.4 1.6 1 1 0 1 1 1 1 Archaebacterial flagellin RAI16-like PF10257.4 AJZ75920.1 - 0.11 11.4 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein DUF4244 PF14029.1 AJZ75920.1 - 0.35 9.9 3.3 0.61 9.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4244) DUF1628 PF07790.6 AJZ75920.1 - 1.7 9.4 8.3 2.2 9.0 3.6 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF1628) Arch_flagellin PF01917.11 AJZ75921.1 - 7.6e-17 61.5 6.6 1.1e-16 61.0 4.6 1.3 1 0 0 1 1 1 1 Archaebacterial flagellin Arch_flagellin PF01917.11 AJZ75922.1 - 5.3e-20 71.8 9.1 6.3e-20 71.5 6.3 1.1 1 0 0 1 1 1 1 Archaebacterial flagellin TPR_1 PF00515.23 AJZ75923.1 - 9.9e-155 496.5 62.9 5.2e-08 32.1 0.1 29.7 30 0 0 30 30 30 26 Tetratricopeptide repeat TPR_11 PF13414.1 AJZ75923.1 - 1e-146 476.7 66.6 8.4e-13 47.7 0.7 17.3 9 2 10 20 20 20 20 TPR repeat TPR_2 PF07719.12 AJZ75923.1 - 1.4e-141 449.3 53.8 5.8e-06 25.8 0.1 30.7 30 1 1 31 31 31 23 Tetratricopeptide repeat TPR_16 PF13432.1 AJZ75923.1 - 1.1e-108 354.0 2.7 7.8e-09 35.9 0.5 17.6 6 3 10 21 21 21 19 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ75923.1 - 2.6e-92 295.8 67.2 1.9e-05 24.1 0.1 28.9 26 4 4 30 30 30 21 Tetratricopeptide repeat TPR_17 PF13431.1 AJZ75923.1 - 1.3e-90 290.1 69.6 0.00013 21.8 0.2 28.6 29 0 0 29 29 29 21 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ75923.1 - 1.6e-82 271.8 33.1 1.2e-07 31.9 0.1 16.7 10 4 9 19 19 19 17 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ75923.1 - 2.6e-82 270.8 74.1 5.9e-12 45.3 1.9 18.9 2 1 22 24 24 24 24 Tetratricopeptide repeat TPR_9 PF13371.1 AJZ75923.1 - 7.1e-77 253.2 0.1 1.9e-09 37.2 0.0 17.2 8 5 8 17 17 17 14 Tetratricopeptide repeat Apc3 PF12895.2 AJZ75923.1 - 1.3e-76 252.7 76.3 5.2e-09 36.1 1.5 15.3 4 4 12 16 16 16 16 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 AJZ75923.1 - 1.1e-72 233.7 0.2 0.026 15.1 0.0 25.5 6 4 22 28 28 27 15 Tetratricopeptide repeat TPR_6 PF13174.1 AJZ75923.1 - 8.5e-62 201.5 15.6 0.00019 21.6 0.0 25.8 28 0 0 28 28 26 10 Tetratricopeptide repeat TPR_7 PF13176.1 AJZ75923.1 - 6e-45 147.5 30.6 0.029 14.1 0.0 25.3 23 5 4 28 28 26 8 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJZ75923.1 - 6.9e-39 131.5 56.4 0.00085 19.1 0.0 24.0 11 8 14 25 25 25 9 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 AJZ75923.1 - 2.4e-24 84.4 13.5 0.088 12.7 0.0 16.4 18 0 0 18 18 16 5 Tetratricopeptide repeat TPR_20 PF14561.1 AJZ75923.1 - 2.6e-15 56.2 22.3 0.42 10.7 0.1 13.7 9 7 3 14 14 14 3 Tetratricopeptide repeat NARP1 PF12569.3 AJZ75923.1 - 2.2e-13 49.8 35.2 0.13 11.0 0.2 12.9 1 1 12 14 14 14 6 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 AJZ75923.1 - 9.5e-12 44.5 21.0 0.054 12.5 0.0 9.6 3 3 4 8 8 8 3 Tetratricopeptide repeat Paf67 PF10255.4 AJZ75923.1 - 1.2e-10 40.8 15.6 0.0023 16.8 0.5 9.0 4 3 5 10 10 10 1 RNA polymerase I-associated factor PAF67 DUF3856 PF12968.2 AJZ75923.1 - 8.4e-10 38.6 17.7 0.094 12.5 0.0 14.1 8 4 9 17 17 17 1 Domain of Unknown Function (DUF3856) PPR PF01535.15 AJZ75923.1 - 4.7e-09 35.6 2.3 6.2 7.0 0.0 11.0 13 0 0 13 13 10 0 PPR repeat Coatomer_E PF04733.9 AJZ75923.1 - 1.3e-08 34.4 30.7 0.69 9.0 0.3 9.9 3 2 7 11 11 11 3 Coatomer epsilon subunit TPR_5 PF12688.2 AJZ75923.1 - 6.6e-07 29.3 11.9 1.8 8.6 0.0 9.2 5 4 5 10 10 10 1 Tetratrico peptide repeat BTAD PF03704.12 AJZ75923.1 - 4e-06 27.1 7.5 1.7 8.9 0.0 8.0 6 2 4 11 11 9 2 Bacterial transcriptional activator domain TPR_4 PF07721.9 AJZ75923.1 - 8.3e-05 22.6 0.2 47 4.8 0.0 7.5 10 0 0 10 10 6 0 Tetratricopeptide repeat MIT PF04212.13 AJZ75923.1 - 0.0013 18.5 31.0 0.72 9.7 0.0 13.6 14 4 4 18 18 15 1 MIT (microtubule interacting and transport) domain YfiO PF13525.1 AJZ75923.1 - 0.0023 17.4 7.0 0.94 8.9 0.2 5.5 4 1 0 4 4 4 1 Outer membrane lipoprotein DUF1910 PF08928.5 AJZ75923.1 - 0.086 12.8 1.9 2.7 8.0 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1910) TPR_1 PF00515.23 AJZ75924.1 - 7.6e-42 139.2 10.3 5.2e-07 28.9 0.0 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 AJZ75924.1 - 6e-38 125.7 10.3 1.3e-06 27.8 0.0 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 AJZ75924.1 - 3.3e-37 125.9 27.8 1.1e-10 41.0 0.0 5.0 2 1 4 6 6 6 6 TPR repeat TPR_16 PF13432.1 AJZ75924.1 - 6e-31 106.4 3.9 4.6e-09 36.6 0.1 5.1 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 AJZ75924.1 - 9e-26 87.8 8.5 0.0024 17.9 0.1 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ75924.1 - 1.7e-25 86.8 9.0 0.0011 18.6 0.0 7.4 7 1 1 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ75924.1 - 2.5e-24 84.9 21.5 4.5e-09 36.1 0.9 5.2 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 AJZ75924.1 - 8.7e-23 78.7 0.1 0.0036 17.7 0.0 7.0 1 1 7 8 8 8 5 Tetratricopeptide repeat TPR_6 PF13174.1 AJZ75924.1 - 4e-20 70.8 1.4 0.0036 17.6 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 AJZ75924.1 - 2.2e-19 69.0 0.0 3.6e-06 26.7 0.0 4.1 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ75924.1 - 7.6e-19 67.8 6.4 4.7e-06 26.8 0.0 4.3 1 1 5 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 AJZ75924.1 - 5.3e-18 64.9 12.5 8.8e-08 32.1 0.8 3.5 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 AJZ75924.1 - 7.9e-14 50.2 3.1 1.7 8.6 0.0 7.4 7 1 1 8 8 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJZ75924.1 - 3.2e-11 42.9 8.4 0.00012 21.8 0.1 4.7 4 1 1 5 5 5 3 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.3 AJZ75924.1 - 2.7e-07 29.7 1.4 0.017 13.8 0.2 3.5 1 1 2 3 3 3 2 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 AJZ75924.1 - 6.7e-07 29.0 0.3 0.088 12.7 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 AJZ75924.1 - 2.5e-06 26.7 2.8 0.012 14.6 0.0 3.8 1 1 1 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.2 AJZ75924.1 - 0.00014 21.7 0.9 3.2 7.5 0.0 5.1 3 2 3 6 6 6 1 Domain of Unknown Function (DUF3856) BTAD PF03704.12 AJZ75924.1 - 0.00024 21.4 0.2 0.79 10.0 0.0 3.5 1 1 2 3 3 3 1 Bacterial transcriptional activator domain TPR_5 PF12688.2 AJZ75924.1 - 0.00036 20.5 0.5 2.8 8.0 0.0 3.5 1 1 1 3 3 3 1 Tetratrico peptide repeat Paf67 PF10255.4 AJZ75924.1 - 0.00052 19.0 0.5 1.7 7.4 0.0 3.2 1 1 1 3 3 3 2 RNA polymerase I-associated factor PAF67 MIT PF04212.13 AJZ75924.1 - 0.0023 17.8 4.5 0.34 10.8 0.0 4.3 5 2 1 6 6 5 1 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 AJZ75924.1 - 0.0035 17.6 0.4 7.8 7.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 AJZ75924.1 - 0.013 15.5 3.5 1.8 8.7 0.0 3.9 2 1 2 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.9 AJZ75924.1 - 0.02 14.1 0.2 0.42 9.7 0.0 2.5 1 1 2 3 3 3 0 Coatomer epsilon subunit DUF3808 PF10300.4 AJZ75924.1 - 0.026 13.0 0.1 0.093 11.2 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3808) DUF627 PF04781.7 AJZ75924.1 - 0.027 14.0 2.7 1.4 8.5 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF627) RPN7 PF10602.4 AJZ75924.1 - 0.035 13.4 1.3 1.3 8.3 0.1 3.4 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_11 PF13414.1 AJZ75925.1 - 6.3e-130 423.0 56.2 4.7e-15 54.9 0.0 9.6 2 1 11 14 14 14 14 TPR repeat TPR_1 PF00515.23 AJZ75925.1 - 8.9e-108 347.9 29.3 1.6e-07 30.6 0.1 16.2 16 0 0 16 16 16 15 Tetratricopeptide repeat TPR_2 PF07719.12 AJZ75925.1 - 2.5e-94 301.7 21.7 6.9e-06 25.5 0.0 16.1 16 0 0 16 16 16 16 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ75925.1 - 7.2e-77 253.3 44.4 2.7e-09 36.8 0.7 9.8 2 2 12 14 14 14 14 Tetratricopeptide repeat TPR_16 PF13432.1 AJZ75925.1 - 2e-70 232.1 0.0 1.4e-09 38.3 0.1 9.6 7 2 2 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.1 AJZ75925.1 - 1.9e-69 224.1 30.3 3.6e-05 23.6 0.0 16.1 17 0 0 17 17 16 15 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ75925.1 - 2.9e-65 211.2 27.7 9e-05 21.9 0.0 15.9 13 3 3 16 16 16 14 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ75925.1 - 2.1e-54 181.7 5.9 5.8e-07 29.7 0.1 10.5 5 2 6 11 11 11 11 Tetratricopeptide repeat TPR_14 PF13428.1 AJZ75925.1 - 1.9e-45 149.1 0.0 0.011 16.2 0.0 15.0 1 1 15 16 16 16 10 Tetratricopeptide repeat Apc3 PF12895.2 AJZ75925.1 - 1e-43 147.3 26.1 6.7e-10 38.9 1.8 7.2 2 2 6 9 9 9 9 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AJZ75925.1 - 3.3e-40 135.7 0.1 2.8e-05 23.9 0.0 9.4 4 2 6 10 10 10 9 Tetratricopeptide repeat TPR_7 PF13176.1 AJZ75925.1 - 9.2e-37 121.9 9.8 0.0022 17.6 0.0 15.1 15 1 1 16 16 16 7 Tetratricopeptide repeat TPR_6 PF13174.1 AJZ75925.1 - 5.3e-36 120.6 1.0 0.051 14.0 0.0 14.9 16 0 0 16 16 16 6 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJZ75925.1 - 2e-27 94.8 20.2 0.014 15.2 0.0 13.6 9 5 6 15 15 14 9 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 AJZ75925.1 - 5e-17 61.2 7.0 4.1 7.4 0.0 12.3 14 0 0 14 14 14 1 Tetratricopeptide repeat DUF3856 PF12968.2 AJZ75925.1 - 8.1e-15 54.9 0.1 5.3 6.8 0.0 11.1 2 1 6 10 10 10 0 Domain of Unknown Function (DUF3856) TPR_5 PF12688.2 AJZ75925.1 - 5.1e-14 52.3 0.7 0.028 14.4 0.0 7.2 2 2 5 9 9 9 4 Tetratrico peptide repeat NARP1 PF12569.3 AJZ75925.1 - 1.9e-12 46.7 7.9 0.097 11.4 0.1 7.6 1 1 6 9 9 9 5 NMDA receptor-regulated protein 1 BTAD PF03704.12 AJZ75925.1 - 2.7e-11 43.9 0.0 3.9 7.7 0.0 7.3 3 2 5 8 8 8 1 Bacterial transcriptional activator domain Coatomer_E PF04733.9 AJZ75925.1 - 2.2e-10 40.1 4.2 0.068 12.3 0.1 5.8 2 2 3 5 5 5 5 Coatomer epsilon subunit TPR_15 PF13429.1 AJZ75925.1 - 1.2e-09 37.6 4.4 0.046 12.7 0.1 7.0 1 1 3 6 6 6 3 Tetratricopeptide repeat TOM20_plant PF06552.7 AJZ75925.1 - 8.3e-07 28.7 2.7 0.62 9.6 0.0 7.5 2 2 7 9 9 9 1 Plant specific mitochondrial import receptor subunit TOM20 Alkyl_sulf_dimr PF14863.1 AJZ75925.1 - 2.5e-06 27.7 0.3 1.2 9.3 0.0 5.6 4 3 3 7 7 7 1 Alkyl sulfatase dimerisation PPR PF01535.15 AJZ75925.1 - 4.3e-06 26.3 4.6 26 5.0 0.0 8.7 11 0 0 11 11 8 0 PPR repeat MIT PF04212.13 AJZ75925.1 - 1e-05 25.2 17.9 0.96 9.3 0.0 9.9 9 4 1 10 10 9 1 MIT (microtubule interacting and transport) domain DUF627 PF04781.7 AJZ75925.1 - 8.6e-05 22.1 10.9 0.31 10.6 0.3 6.3 6 3 2 8 8 7 2 Protein of unknown function (DUF627) TPR_4 PF07721.9 AJZ75925.1 - 0.015 15.6 0.0 15 6.3 0.0 5.4 8 0 0 8 8 3 0 Tetratricopeptide repeat Paf67 PF10255.4 AJZ75925.1 - 0.041 12.7 0.3 2.8 6.7 0.0 3.7 2 2 3 5 5 5 0 RNA polymerase I-associated factor PAF67 EST1_DNA_bind PF10373.4 AJZ75925.1 - 3 6.9 9.8 0.96 8.6 0.1 3.7 5 0 0 5 5 5 0 Est1 DNA/RNA binding domain DUF4480 PF13715.1 AJZ75926.1 - 0.015 15.3 2.9 2 8.5 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4480) CBS PF00571.23 AJZ75927.1 - 1.1e-05 25.0 1.0 1.4 8.7 0.0 3.9 4 0 0 4 4 4 3 CBS domain Cas_CXXC_CXXC PF09706.5 AJZ75927.1 - 0.078 13.1 0.1 9.7 6.4 0.0 2.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) OTCace_N PF02729.16 AJZ75928.1 - 2.2e-38 131.1 0.0 3.5e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 AJZ75928.1 - 3.8e-37 127.6 0.0 5.4e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PyrI PF01948.13 AJZ75929.1 - 1e-34 118.4 1.6 1.8e-34 117.6 1.1 1.4 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.10 AJZ75929.1 - 1.6e-15 56.2 3.4 2.5e-15 55.6 2.4 1.3 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF1936 PF09151.5 AJZ75929.1 - 0.018 14.5 0.3 0.018 14.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) ATP-synt_C PF00137.16 AJZ75930.1 - 1.7e-20 72.6 16.4 1.7e-20 72.6 11.4 1.7 2 0 0 2 2 2 1 ATP synthase subunit C ATP-synt_D PF01813.12 AJZ75931.1 - 2.8e-51 173.8 6.6 3.2e-51 173.7 4.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit D STAT_alpha PF01017.15 AJZ75931.1 - 0.12 12.1 1.8 1.7 8.2 0.1 2.4 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF1019 PF06254.6 AJZ75931.1 - 1.7 8.8 8.4 0.3 11.2 0.8 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1019) ATP-synt_ab PF00006.20 AJZ75932.1 - 7.8e-64 215.1 0.0 1.1e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 AJZ75932.1 - 5.6e-10 39.2 1.5 5.6e-10 39.2 1.0 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 AJZ75932.1 - 7e-10 39.3 0.2 1.4e-09 38.4 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain HAS-barrel PF09378.5 AJZ75932.1 - 0.00011 22.0 0.6 0.00036 20.3 0.4 1.9 1 0 0 1 1 1 1 HAS barrel domain ATP-synt_ab PF00006.20 AJZ75933.1 - 1.2e-96 322.3 0.0 1.6e-96 321.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AJZ75933.1 - 6.8e-15 55.5 0.5 1.3e-14 54.5 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AJZ75933.1 - 7.4e-13 48.5 0.2 1.8e-12 47.2 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.1 AJZ75933.1 - 0.0022 17.6 0.2 0.15 11.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain ATP_bind_2 PF03668.10 AJZ75933.1 - 0.043 12.8 0.0 0.12 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop ATPase protein family AAA_22 PF13401.1 AJZ75933.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.7 AJZ75933.1 - 0.097 11.0 0.4 0.16 10.3 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) vATP-synt_E PF01991.13 AJZ75934.1 - 1.5e-22 79.8 14.5 6.7e-22 77.7 10.0 2.0 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Dehydratase_LU PF02286.10 AJZ75934.1 - 0.053 11.7 0.2 0.062 11.5 0.1 1.1 1 0 0 1 1 1 0 Dehydratase large subunit RHD3 PF05879.7 AJZ75934.1 - 0.087 10.7 7.5 0.1 10.5 5.2 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DnaG_DnaB_bind PF08278.6 AJZ75934.1 - 0.22 11.7 8.0 0.16 12.1 0.9 2.4 1 1 1 2 2 2 0 DNA primase DnaG DnaB-binding DUF4294 PF14127.1 AJZ75934.1 - 0.23 11.0 4.6 0.18 11.4 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4294) ATP-synt_B PF00430.13 AJZ75934.1 - 0.55 10.0 12.1 0.94 9.2 7.5 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) IncA PF04156.9 AJZ75934.1 - 1.2 8.6 10.3 1.6 8.3 7.1 1.2 1 0 0 1 1 1 0 IncA protein LMBR1 PF04791.11 AJZ75934.1 - 1.5 7.3 4.3 1.7 7.1 3.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Spore_III_AB PF09548.5 AJZ75934.1 - 1.6 8.4 8.6 4.8 6.9 5.5 2.0 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PP2C_C PF07830.8 AJZ75934.1 - 2.5 8.2 5.4 15 5.7 0.2 2.9 2 1 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain V_ATPase_I PF01496.14 AJZ75935.1 - 3.4e-51 174.0 9.8 4e-50 170.5 6.8 1.9 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF624 PF04854.9 AJZ75935.1 - 0.0067 16.2 1.1 0.02 14.7 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF624 MerR-DNA-bind PF09278.6 AJZ75935.1 - 0.11 12.8 0.2 19 5.7 0.0 2.5 2 0 0 2 2 2 0 MerR, DNA binding Rhodanese PF00581.15 AJZ75936.1 - 2.9e-45 153.2 0.2 6.5e-23 81.2 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Ammonium_transp PF00909.16 AJZ75937.1 - 8.8e-112 373.4 33.2 2.1e-111 372.1 23.0 1.6 1 1 0 1 1 1 1 Ammonium Transporter Family vATP-synt_AC39 PF01992.11 AJZ75939.1 - 7e-39 133.8 7.8 7.9e-39 133.7 5.4 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit MerR-DNA-bind PF09278.6 AJZ75939.1 - 0.073 13.4 2.3 0.12 12.7 0.2 2.5 3 0 0 3 3 3 0 MerR, DNA binding FPL PF09758.4 AJZ75939.1 - 0.087 12.5 2.3 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein DUF3799 PF12684.2 AJZ75939.1 - 0.092 12.0 0.7 0.22 10.8 0.1 1.8 2 0 0 2 2 2 0 PDDEXK-like domain of unknown function (DUF3799) ABC2_membrane_4 PF12730.2 AJZ75940.1 - 0.0019 17.4 2.6 0.0019 17.4 1.8 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein Peptidase_A24 PF01478.13 AJZ75940.1 - 0.017 15.2 0.7 0.022 14.9 0.5 1.1 1 0 0 1 1 1 0 Type IV leader peptidase family Cas_Cas4 PF01930.12 AJZ75941.1 - 4.9e-05 23.2 0.5 6.8e-05 22.8 0.0 1.6 2 1 0 2 2 2 1 Domain of unknown function DUF83 TGT PF01702.13 AJZ75941.1 - 0.072 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase PDDEXK_1 PF12705.2 AJZ75941.1 - 0.17 11.2 1.4 0.89 8.8 0.8 1.9 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Neugrin PF06413.6 AJZ75942.1 - 0.012 15.4 0.6 0.019 14.8 0.4 1.3 1 0 0 1 1 1 0 Neugrin DUF1664 PF07889.7 AJZ75942.1 - 0.018 14.8 4.5 0.71 9.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Focal_AT PF03623.8 AJZ75942.1 - 0.018 14.5 0.5 0.9 9.0 0.0 2.2 2 0 0 2 2 2 0 Focal adhesion targeting region SlyX PF04102.7 AJZ75942.1 - 0.053 13.8 11.2 0.31 11.4 1.8 3.3 2 2 1 3 3 3 0 SlyX DUF2408 PF10303.4 AJZ75942.1 - 0.13 12.3 5.0 0.43 10.6 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) COG2 PF06148.6 AJZ75942.1 - 0.14 12.0 7.1 0.49 10.2 0.2 2.5 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CHASE3 PF05227.8 AJZ75942.1 - 0.17 11.5 5.6 0.7 9.5 0.2 2.2 2 0 0 2 2 2 0 CHASE3 domain TENA_THI-4 PF03070.11 AJZ75942.1 - 0.21 11.3 1.3 0.45 10.2 0.9 1.8 1 1 0 1 1 1 0 TENA/THI-4/PQQC family IncA PF04156.9 AJZ75942.1 - 0.46 10.0 13.5 0.22 11.1 2.3 2.2 1 1 1 2 2 2 0 IncA protein TBPIP PF07106.8 AJZ75942.1 - 0.48 9.9 7.7 4.6 6.7 1.4 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 AJZ75942.1 - 0.97 7.8 5.8 1.8 6.9 0.6 2.0 1 1 0 2 2 2 0 AAA domain Occludin_ELL PF07303.8 AJZ75942.1 - 1.8 9.3 5.2 5.8 7.7 0.5 2.4 1 1 1 2 2 2 0 Occludin homology domain Rsa3 PF14615.1 AJZ75942.1 - 2 7.7 4.6 1.6 8.1 0.5 2.6 3 0 0 3 3 3 0 Ribosome-assembly protein 3 Dzip-like_N PF13815.1 AJZ75942.1 - 2.1 8.1 7.2 8.3 6.2 1.0 2.3 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DnaG_DnaB_bind PF08278.6 AJZ75942.1 - 2.3 8.4 7.3 0.64 10.2 0.5 2.4 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding Fib_alpha PF08702.5 AJZ75942.1 - 4 7.5 6.3 21 5.2 1.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.9 AJZ75942.1 - 8 6.0 9.3 11 5.6 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) LEA_2 PF03168.8 AJZ75943.1 - 0.032 14.5 0.0 0.084 13.2 0.0 1.8 1 1 0 1 1 1 0 Late embryogenesis abundant protein DUF4352 PF11611.3 AJZ75943.1 - 0.051 13.7 0.3 3.4 7.8 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4352) HD PF01966.17 AJZ75944.1 - 1.7e-15 57.0 0.2 3.7e-15 56.0 0.2 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 AJZ75944.1 - 0.047 12.9 0.1 0.12 11.6 0.1 1.6 1 1 0 1 1 1 0 HDOD domain Cnl2_NKP2 PF09447.5 AJZ75944.1 - 1.2 8.8 4.5 0.47 10.1 0.5 2.2 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Thymidylate_kin PF02223.12 AJZ75945.1 - 2.2e-34 118.4 0.1 2.5e-34 118.2 0.1 1.0 1 0 0 1 1 1 1 Thymidylate kinase HSP20 PF00011.16 AJZ75947.1 - 3.8e-13 49.1 0.4 5e-13 48.7 0.3 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Bunya_NS-S_2 PF03231.8 AJZ75947.1 - 0.0042 15.7 0.3 0.0042 15.7 0.2 1.1 1 0 0 1 1 1 1 Bunyavirus non-structural protein NS-S CS PF04969.11 AJZ75947.1 - 0.13 12.8 1.3 0.34 11.4 0.2 2.1 2 0 0 2 2 2 0 CS domain ABC1 PF03109.11 AJZ75948.1 - 7.9e-25 87.1 0.3 3.7e-24 84.9 0.0 2.2 3 0 0 3 3 3 1 ABC1 family APH PF01636.18 AJZ75948.1 - 0.0056 16.4 0.1 0.069 12.8 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 AJZ75948.1 - 0.0099 15.0 0.7 0.023 13.8 0.5 1.7 1 1 0 1 1 1 1 Protein kinase domain NAAA-beta PF15508.1 AJZ75948.1 - 0.083 13.2 0.9 11 6.4 0.0 3.5 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CARDB PF07705.6 AJZ75949.1 - 0.00014 21.8 6.7 0.015 15.3 4.1 3.7 2 1 3 5 5 5 1 CARDB NPCBM_assoc PF10633.4 AJZ75949.1 - 0.00032 20.6 3.6 0.4 10.7 0.1 4.2 4 0 0 4 4 4 2 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF4366 PF14283.1 AJZ75949.1 - 0.075 12.4 0.1 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Arrestin_C PF02752.17 AJZ75949.1 - 0.15 12.1 4.4 2 8.5 2.2 2.6 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain DUF11 PF01345.13 AJZ75949.1 - 0.17 11.9 6.0 0.56 10.3 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF11 MacB_PCD PF12704.2 AJZ75950.1 - 1.1e-20 74.2 0.7 2.3e-20 73.2 0.5 1.5 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.16 AJZ75950.1 - 4.7e-19 68.3 7.2 4.7e-19 68.3 5.0 1.9 2 0 0 2 2 2 1 FtsX-like permease family HTH_24 PF13412.1 AJZ75951.1 - 4.3e-18 64.4 5.5 5.9e-09 35.1 1.0 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AJZ75951.1 - 5e-18 64.3 1.6 1.3e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain TrmB PF01978.14 AJZ75951.1 - 8.7e-07 28.5 0.0 0.00022 20.8 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 AJZ75951.1 - 1.3e-06 27.9 0.0 0.00032 20.2 0.0 2.3 2 0 0 2 2 2 1 MarR family MarR PF01047.17 AJZ75951.1 - 1.8e-06 27.5 3.0 0.00032 20.3 0.3 2.6 3 0 0 3 3 2 2 MarR family HTH_5 PF01022.15 AJZ75951.1 - 1.8e-05 24.3 0.8 3.8e-05 23.2 0.0 2.0 2 0 0 2 2 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.7 AJZ75951.1 - 3e-05 23.5 2.2 0.0004 19.9 0.4 2.5 2 0 0 2 2 2 1 HTH domain HTH_Mga PF08280.6 AJZ75951.1 - 5.2e-05 22.9 1.4 0.00024 20.7 0.7 2.3 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain Mga PF05043.8 AJZ75951.1 - 6.7e-05 23.0 0.1 0.019 15.2 0.1 2.7 2 0 0 2 2 2 1 Mga helix-turn-helix domain TFIIE_alpha PF02002.12 AJZ75951.1 - 0.00039 19.8 0.3 0.0035 16.8 0.0 2.3 2 0 0 2 2 2 1 TFIIE alpha subunit HTH_9 PF08221.6 AJZ75951.1 - 0.00043 20.0 0.5 0.26 11.1 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_27 PF13463.1 AJZ75951.1 - 0.0019 18.4 0.3 0.23 11.8 0.1 2.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_41 PF14502.1 AJZ75951.1 - 0.0035 16.9 0.0 0.0077 15.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HxlR PF01638.12 AJZ75951.1 - 0.0035 16.9 0.1 0.82 9.3 0.0 2.4 2 0 0 2 2 2 1 HxlR-like helix-turn-helix Trp_repressor PF01371.14 AJZ75951.1 - 0.0037 17.1 1.1 0.47 10.3 0.0 2.7 3 0 0 3 3 2 1 Trp repressor protein HTH_23 PF13384.1 AJZ75951.1 - 0.009 15.6 0.1 2.5 7.8 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 AJZ75951.1 - 0.016 15.0 0.3 0.11 12.3 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_DeoR PF08220.7 AJZ75951.1 - 0.018 14.5 0.3 0.048 13.1 0.2 1.8 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_26 PF13443.1 AJZ75951.1 - 0.02 15.0 0.4 0.057 13.6 0.3 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_36 PF13730.1 AJZ75951.1 - 0.029 14.4 0.2 0.08 13.0 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_34 PF13601.1 AJZ75951.1 - 0.033 14.2 1.2 4.7 7.3 0.1 2.6 3 0 0 3 3 2 0 Winged helix DNA-binding domain HTH_Crp_2 PF13545.1 AJZ75951.1 - 0.035 13.9 0.1 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_38 PF13936.1 AJZ75951.1 - 0.073 12.6 0.4 0.22 11.1 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain WhiA_N PF10298.4 AJZ75951.1 - 0.074 12.9 0.1 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain HTH_10 PF04967.7 AJZ75951.1 - 0.1 12.1 0.6 2 8.0 0.1 2.5 2 0 0 2 2 2 0 HTH DNA binding domain DUF1161 PF06649.7 AJZ75951.1 - 0.32 10.9 1.6 1.9 8.4 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1161) NUDIX PF00293.23 AJZ75952.1 - 4.8e-18 65.1 0.0 6.2e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain AF0941-like PF14591.1 AJZ75952.1 - 0.039 14.0 0.6 0.066 13.2 0.1 1.5 2 0 0 2 2 2 0 AF0941-like PhoU PF01895.14 AJZ75953.1 - 4.1e-11 43.1 11.8 3.9e-08 33.6 1.7 2.7 2 0 0 2 2 2 2 PhoU domain Antitoxin-MazE PF04014.13 AJZ75953.1 - 1.1e-06 28.1 0.0 2.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Antidote-toxin recognition MazE DUF4423 PF14394.1 AJZ75953.1 - 0.011 15.3 0.8 1.2 8.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) GHMP_kinases_N PF00288.21 AJZ75954.1 - 1.4e-10 41.0 0.1 2.7e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AJZ75954.1 - 0.051 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal Spore_YpjB PF09577.5 AJZ75954.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DUF137 PF02006.11 AJZ75955.1 - 1.4e-65 220.0 2.2 2e-65 219.4 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF137 TPP_enzyme_M PF00205.17 AJZ75955.1 - 0.027 14.2 0.6 0.25 11.0 0.4 2.2 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Pantoate_transf PF02548.10 AJZ75956.1 - 1.6e-108 361.8 3.6 1.8e-108 361.6 2.5 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 AJZ75956.1 - 1.3e-05 24.5 1.3 4.9e-05 22.6 0.9 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DFP PF04127.10 AJZ75957.1 - 1.9e-57 193.8 2.1 6e-55 185.7 0.5 2.6 3 0 0 3 3 3 2 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.14 AJZ75957.1 - 3.1e-26 91.5 0.6 3.1e-26 91.5 0.4 1.9 2 0 0 2 2 2 1 Flavoprotein NAD_binding_7 PF13241.1 AJZ75957.1 - 0.0056 16.9 0.3 0.23 11.7 0.0 2.9 2 1 0 2 2 2 1 Putative NAD(P)-binding BRCT PF00533.21 AJZ75957.1 - 0.02 15.0 0.1 0.19 11.9 0.0 2.7 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Glyco_transf_4 PF13439.1 AJZ75957.1 - 0.055 13.1 0.0 3.4 7.3 0.0 2.6 2 1 0 2 2 2 0 Glycosyltransferase Family 4 NAD_binding_10 PF13460.1 AJZ75957.1 - 0.066 13.2 0.0 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding YjeF_N PF03853.10 AJZ75957.1 - 0.087 12.4 0.0 4.8 6.7 0.0 2.6 3 0 0 3 3 3 0 YjeF-related protein N-terminus Pyr_redox PF00070.22 AJZ75957.1 - 0.088 13.2 1.9 44 4.5 0.0 3.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Beta_propel PF09826.4 AJZ75958.1 - 4.2e-163 543.4 12.2 5e-163 543.1 8.4 1.0 1 0 0 1 1 1 1 Beta propeller domain GHL12 PF14882.1 AJZ75958.1 - 0.0053 16.8 0.6 0.98 9.5 0.0 3.6 3 0 0 3 3 3 1 Hypothetical glycosyl hydrolase 12 Catalase-rel PF06628.7 AJZ75958.1 - 0.079 12.8 0.4 6.1 6.7 0.0 2.4 1 1 1 2 2 2 0 Catalase-related immune-responsive DUF4600 PF15372.1 AJZ75958.1 - 0.19 11.9 4.6 0.38 10.9 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Aldedh PF00171.17 AJZ75959.1 - 2.4e-134 448.1 0.0 3e-134 447.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DndB PF14072.1 AJZ75960.1 - 7.9e-12 44.9 7.0 7.9e-12 44.9 4.8 2.6 2 1 0 2 2 2 1 DNA-sulfur modification-associated Hjc PF01870.13 AJZ75960.1 - 0.0069 15.9 0.0 0.02 14.5 0.0 1.8 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) Helicase_C_2 PF13307.1 AJZ75961.1 - 1.3e-17 64.2 0.0 2.8e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 AJZ75961.1 - 1.5e-11 44.4 2.1 7.4e-11 42.2 0.0 2.8 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 AJZ75961.1 - 0.00013 21.4 0.1 0.00013 21.4 0.1 2.3 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.24 AJZ75961.1 - 0.00022 20.7 0.0 0.18 11.3 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.11 AJZ75961.1 - 0.0051 16.0 0.0 0.0094 15.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein IstB_IS21 PF01695.12 AJZ75961.1 - 0.0081 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 AJZ75961.1 - 0.018 15.2 0.0 11 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 AJZ75961.1 - 0.046 12.4 0.0 0.093 11.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_30 PF13604.1 AJZ75961.1 - 0.23 10.9 0.0 20 4.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.19 AJZ75962.1 - 1.8e-11 43.8 0.0 5.2e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 AJZ75962.1 - 1.3e-09 38.3 0.2 2.2e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AJZ75962.1 - 4.7e-07 29.8 0.0 1.4e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AJZ75962.1 - 1.2e-05 25.3 0.0 3.7e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AJZ75962.1 - 3.8e-05 23.3 0.0 6.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 AJZ75962.1 - 0.00027 20.8 0.0 0.00057 19.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AJZ75962.1 - 0.0013 18.5 0.0 0.015 15.1 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AJZ75962.1 - 0.08 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Gly_acyl_tr_C PF08444.5 AJZ75962.1 - 0.089 12.8 0.3 0.7 9.9 0.0 2.3 1 1 1 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF1510 PF07423.6 AJZ75963.1 - 0.0014 18.0 4.5 0.0017 17.8 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SID-1_RNA_chan PF13965.1 AJZ75963.1 - 0.044 11.9 0.7 0.048 11.8 0.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 OATP PF03137.15 AJZ75963.1 - 0.059 11.4 0.7 0.068 11.2 0.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2201_N PF13203.1 AJZ75963.1 - 0.065 12.4 0.3 0.07 12.2 0.2 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain RNase_H2-Ydr279 PF09468.5 AJZ75963.1 - 0.098 11.8 10.3 0.097 11.8 7.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) HSP90 PF00183.13 AJZ75963.1 - 0.14 10.4 11.8 0.15 10.4 8.2 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF106 PF01956.11 AJZ75963.1 - 0.22 11.0 1.0 0.26 10.8 0.7 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 SspB PF04386.8 AJZ75963.1 - 0.4 10.2 3.0 0.49 9.9 2.1 1.3 1 0 0 1 1 1 0 Stringent starvation protein B Sec62 PF03839.11 AJZ75963.1 - 0.48 9.8 9.0 0.53 9.6 6.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 YqfQ PF14181.1 AJZ75963.1 - 0.58 10.1 15.5 0.75 9.8 10.7 1.0 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.7 AJZ75963.1 - 2.6 7.8 10.0 2.9 7.7 7.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 AJZ75963.1 - 6.7 5.3 14.1 7.6 5.1 9.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-C2H2_4 PF13894.1 AJZ75964.1 - 0.00028 20.9 7.8 0.13 12.6 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-FCS PF06467.9 AJZ75964.1 - 0.00095 18.7 1.4 0.36 10.5 0.1 2.1 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif DZR PF12773.2 AJZ75964.1 - 0.0018 18.0 0.6 0.0026 17.5 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C2H2 PF00096.21 AJZ75964.1 - 0.0057 16.9 8.4 0.062 13.6 0.6 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type TFIIS_C PF01096.13 AJZ75964.1 - 0.022 14.3 0.5 0.034 13.7 0.3 1.3 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) DUF678 PF05077.7 AJZ75964.1 - 0.031 14.2 0.3 0.062 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF678) zf-Di19 PF05605.7 AJZ75964.1 - 0.033 14.2 7.2 0.074 13.1 5.0 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.17 AJZ75964.1 - 0.035 14.1 5.0 0.043 13.8 3.4 1.2 1 0 0 1 1 1 0 LIM domain zf-C3HC PF07967.8 AJZ75964.1 - 0.04 13.6 3.2 0.22 11.3 0.2 2.0 1 1 1 2 2 2 0 C3HC zinc finger-like zf-ribbon_3 PF13248.1 AJZ75964.1 - 0.051 12.8 0.6 1.9 7.7 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 AJZ75964.1 - 0.063 13.0 3.9 1.5 8.6 0.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-DNA_Pol PF08996.5 AJZ75964.1 - 0.084 12.2 1.7 0.088 12.1 1.1 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Lar_restr_allev PF14354.1 AJZ75964.1 - 0.09 13.0 0.4 0.13 12.6 0.3 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar Ribosomal_S27e PF01667.12 AJZ75964.1 - 0.14 11.7 1.0 0.22 11.1 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein S27 zinc_ribbon_4 PF13717.1 AJZ75964.1 - 0.16 11.7 4.0 1.5 8.6 2.8 2.2 1 1 0 1 1 1 0 zinc-ribbon domain DUF3795 PF12675.2 AJZ75964.1 - 0.17 12.0 2.7 0.2 11.8 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Yippee-Mis18 PF03226.9 AJZ75964.1 - 0.2 11.6 1.6 0.41 10.7 1.1 1.5 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly A2L_zn_ribbon PF08792.5 AJZ75964.1 - 0.23 10.9 3.0 0.99 8.9 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_5 PF13719.1 AJZ75964.1 - 0.26 10.9 4.4 2.2 7.9 3.0 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf-met PF12874.2 AJZ75964.1 - 0.32 11.2 6.3 1.4 9.1 1.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-DNL PF05180.7 AJZ75964.1 - 0.41 10.3 3.4 0.53 10.0 2.3 1.2 1 0 0 1 1 1 0 DNL zinc finger DUF581 PF04570.9 AJZ75964.1 - 0.42 9.9 3.0 5.9 6.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF581) zf-C2HC5 PF06221.8 AJZ75964.1 - 0.64 9.8 4.2 10 5.9 0.3 2.2 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-BED PF02892.10 AJZ75964.1 - 0.91 9.3 6.9 7.8 6.3 0.8 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.2 AJZ75964.1 - 1.2 9.3 10.4 0.3 11.2 2.5 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 AJZ75964.1 - 1.4 8.9 5.2 7.7 6.5 0.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-DBF PF07535.7 AJZ75964.1 - 1.4 8.6 7.6 0.26 11.0 2.7 1.7 1 1 1 2 2 2 0 DBF zinc finger zinc_ribbon_2 PF13240.1 AJZ75964.1 - 1.7 8.2 5.5 16 5.1 3.8 2.1 1 1 0 1 1 1 0 zinc-ribbon domain FYVE PF01363.16 AJZ75964.1 - 2.3 8.1 6.8 2 8.3 1.0 2.1 1 1 1 2 2 2 0 FYVE zinc finger HTH_45 PF14947.1 AJZ75965.1 - 6.8e-10 38.6 0.3 9.3e-10 38.1 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix Ftsk_gamma PF09397.5 AJZ75965.1 - 0.0029 17.2 0.0 0.004 16.8 0.0 1.2 1 0 0 1 1 1 1 Ftsk gamma domain HTH_24 PF13412.1 AJZ75965.1 - 0.016 14.5 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding P-II PF00543.17 AJZ75966.1 - 3.3e-06 27.5 0.0 1.4e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Nitrogen regulatory protein P-II PM0188 PF11477.3 AJZ75966.1 - 0.024 13.4 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Sialyltransferase PMO188 Pyr_redox_2 PF07992.9 AJZ75967.1 - 7.8e-16 58.5 0.0 1.6e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AJZ75967.1 - 1.4e-15 57.4 0.3 2.3e-10 40.6 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AJZ75967.1 - 0.0014 17.5 2.0 3.5 6.4 0.0 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AJZ75967.1 - 0.013 15.2 0.0 13 5.5 0.0 3.1 2 1 1 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AJZ75967.1 - 0.034 14.1 0.1 0.27 11.2 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AJZ75967.1 - 0.19 10.5 1.6 5.9 5.6 0.3 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF2283 PF10049.4 AJZ75968.1 - 6.8e-09 35.4 0.0 9.6e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2283) DUF4258 PF14076.1 AJZ75969.1 - 0.0039 17.1 0.1 0.0049 16.8 0.1 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4258) NS3_envE PF02723.9 AJZ75969.1 - 0.31 10.9 0.2 0.31 10.9 0.1 1.7 1 1 1 2 2 2 0 Non-structural protein NS3/Small envelope protein E TOBE PF03459.12 AJZ75970.1 - 0.032 14.3 0.0 0.079 13.0 0.0 1.7 2 0 0 2 2 2 0 TOBE domain ACT_7 PF13840.1 AJZ75971.1 - 0.00028 20.3 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 ACT domain SNF2_assoc PF08455.5 AJZ75971.1 - 0.0015 17.1 3.9 0.0026 16.4 2.7 1.3 1 0 0 1 1 1 1 Bacterial SNF2 helicase associated SecD-TM1 PF13721.1 AJZ75971.1 - 0.029 14.6 0.3 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 SecD export protein N-terminal TM region HSP20 PF00011.16 AJZ75972.1 - 4.3e-10 39.3 3.9 1.2e-08 34.6 2.7 2.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family AAA PF00004.24 AJZ75973.1 - 4.7e-100 330.9 0.0 1.9e-49 167.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AJZ75973.1 - 1.3e-19 69.9 0.1 4.8e-19 68.0 0.1 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 AJZ75973.1 - 1.3e-17 64.2 0.0 1.8e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 AJZ75973.1 - 5.7e-15 55.2 0.3 8.4e-07 28.7 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 AJZ75973.1 - 6e-15 54.9 0.1 2.1e-08 33.5 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AJZ75973.1 - 9.5e-14 51.7 0.0 4.1e-06 26.9 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 AJZ75973.1 - 2.1e-12 47.2 1.6 0.001 19.1 0.0 4.5 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AJZ75973.1 - 3.6e-12 47.1 0.0 2.7e-05 24.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 AJZ75973.1 - 5.1e-11 42.5 0.0 0.00025 20.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 AJZ75973.1 - 3.2e-10 39.2 0.1 0.00038 19.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 AJZ75973.1 - 8.7e-10 38.0 0.1 0.00043 19.4 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_33 PF13671.1 AJZ75973.1 - 2.6e-09 37.0 0.0 0.00028 20.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 AJZ75973.1 - 7e-09 35.3 0.1 0.0039 16.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 AJZ75973.1 - 9.1e-09 35.7 0.1 0.00046 20.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 AJZ75973.1 - 2.8e-08 33.2 0.2 7.5e-08 31.9 0.1 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_19 PF13245.1 AJZ75973.1 - 4e-08 32.9 2.9 0.0074 16.0 0.2 3.1 3 0 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 AJZ75973.1 - 6.6e-08 31.9 0.3 0.0063 15.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 AJZ75973.1 - 1.5e-07 31.5 0.0 0.021 15.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 AJZ75973.1 - 3.2e-07 30.4 0.1 0.016 15.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 AJZ75973.1 - 4.9e-07 29.3 0.4 0.19 11.1 0.0 4.5 3 2 0 3 3 3 2 Sigma-54 interaction domain AAA_25 PF13481.1 AJZ75973.1 - 1.9e-06 27.4 6.9 0.12 11.8 0.7 4.4 2 2 0 3 3 3 2 AAA domain Sigma54_activ_2 PF14532.1 AJZ75973.1 - 3e-06 27.3 0.0 0.14 12.2 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 AJZ75973.1 - 4.7e-06 26.2 0.0 0.049 13.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 AJZ75973.1 - 5.5e-06 26.1 3.2 0.044 13.3 0.2 2.8 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 AJZ75973.1 - 6.9e-06 26.4 0.0 0.23 11.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter Parvo_NS1 PF01057.12 AJZ75973.1 - 1.2e-05 24.2 0.2 0.03 13.2 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.8 AJZ75973.1 - 1.3e-05 24.2 0.0 0.095 11.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 AJZ75973.1 - 1.9e-05 24.5 2.0 0.026 14.2 0.0 4.1 2 2 2 4 4 4 1 Archaeal ATPase PhoH PF02562.11 AJZ75973.1 - 4.4e-05 22.8 0.5 0.25 10.5 0.1 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.1 AJZ75973.1 - 5.7e-05 22.7 0.5 0.16 11.5 0.0 2.8 3 1 0 3 3 2 2 AAA domain KaiC PF06745.8 AJZ75973.1 - 5.8e-05 22.3 1.9 0.48 9.5 0.0 3.7 2 1 1 3 3 3 2 KaiC NTPase_1 PF03266.10 AJZ75973.1 - 0.00016 21.4 1.6 2.3 7.9 0.0 4.1 2 1 1 3 3 3 1 NTPase Bac_DnaA PF00308.13 AJZ75973.1 - 0.00021 20.9 0.0 0.053 13.1 0.0 3.0 3 1 0 3 3 2 1 Bacterial dnaA protein NB-ARC PF00931.17 AJZ75973.1 - 0.00024 20.0 0.2 0.29 9.9 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain AAA_30 PF13604.1 AJZ75973.1 - 0.00026 20.6 0.1 0.19 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 AJZ75973.1 - 0.0003 19.8 0.1 0.6 9.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 AJZ75973.1 - 0.00081 19.0 1.8 1.5 8.4 0.0 3.8 3 2 1 4 4 4 1 NACHT domain ResIII PF04851.10 AJZ75973.1 - 0.0013 18.6 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit KAP_NTPase PF07693.9 AJZ75973.1 - 0.0018 17.3 0.1 0.71 8.7 0.0 3.1 2 1 1 3 3 3 1 KAP family P-loop domain T2SE PF00437.15 AJZ75973.1 - 0.0027 16.6 0.0 2.1 7.2 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein ATP-synt_ab PF00006.20 AJZ75973.1 - 0.0029 17.1 0.0 0.51 9.7 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Guanylate_kin PF00625.16 AJZ75973.1 - 0.0031 16.9 1.4 11 5.4 0.0 4.5 5 1 1 6 6 4 0 Guanylate kinase UPF0079 PF02367.12 AJZ75973.1 - 0.0055 16.3 2.4 2.4 7.8 0.0 2.8 3 0 0 3 3 2 2 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 AJZ75973.1 - 0.0075 16.1 0.1 0.65 9.8 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase KTI12 PF08433.5 AJZ75973.1 - 0.017 14.3 0.1 2.1 7.4 0.0 2.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CPT PF07931.7 AJZ75973.1 - 0.033 13.8 0.2 1.2 8.6 0.0 2.8 2 1 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein PIF1 PF05970.9 AJZ75973.1 - 0.039 12.8 0.0 3.6 6.4 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase IPT PF01745.11 AJZ75973.1 - 0.058 12.5 0.3 3.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Isopentenyl transferase AAA_21 PF13304.1 AJZ75973.1 - 0.066 13.1 2.6 4.8 7.0 0.0 3.2 2 2 0 2 2 2 0 AAA domain PPV_E1_C PF00519.12 AJZ75973.1 - 0.075 11.6 0.0 1.1 7.8 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase Viral_helicase1 PF01443.13 AJZ75973.1 - 0.075 12.5 0.0 1.4 8.4 0.0 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AFG1_ATPase PF03969.11 AJZ75973.1 - 0.094 11.5 0.1 4.5 5.9 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase AAA_23 PF13476.1 AJZ75973.1 - 0.28 11.4 7.6 4.7 7.4 0.0 3.7 2 1 1 3 3 3 0 AAA domain Vps4_C PF09336.5 AJZ75973.1 - 0.31 10.9 2.9 5.2 7.0 0.0 3.4 4 0 0 4 4 2 0 Vps4 C terminal oligomerisation domain Polyketide_cyc2 PF10604.4 AJZ75974.1 - 5.4e-05 23.3 0.0 5.9e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AJZ75974.1 - 0.058 13.3 0.0 0.069 13.1 0.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Chlam_PMP PF02415.12 AJZ75974.1 - 0.11 12.8 0.5 0.22 11.8 0.4 1.5 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Fer4 PF00037.22 AJZ75975.1 - 8.9e-11 40.9 11.2 4.3e-07 29.2 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AJZ75975.1 - 1.6e-09 37.9 4.2 2.2e-09 37.5 2.9 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 AJZ75975.1 - 1.9e-08 33.8 9.6 3.7e-05 23.4 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 AJZ75975.1 - 1.5e-07 31.1 3.3 2.6e-07 30.3 2.4 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 AJZ75975.1 - 5.7e-07 29.0 8.4 0.0032 17.2 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 AJZ75975.1 - 1.3e-06 28.1 4.0 2e-06 27.5 2.8 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.2 AJZ75975.1 - 1.8e-05 24.6 7.8 0.03 14.6 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 AJZ75975.1 - 2e-05 24.7 8.5 0.00021 21.4 6.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 AJZ75975.1 - 6.8e-05 23.5 0.9 0.17 12.6 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 AJZ75975.1 - 8.1e-05 22.9 12.3 0.043 14.3 2.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 AJZ75975.1 - 8.7e-05 22.8 5.0 0.14 12.5 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_8 PF13183.1 AJZ75975.1 - 0.00022 21.1 4.0 0.0006 19.7 2.8 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 AJZ75975.1 - 0.00026 21.4 9.5 0.014 15.9 0.7 2.7 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 AJZ75975.1 - 0.00032 21.0 5.9 0.024 15.0 1.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 AJZ75975.1 - 0.0026 18.0 5.6 0.056 13.7 3.8 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Aminotran_5 PF00266.14 AJZ75976.1 - 4e-65 219.9 0.0 4.8e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 AJZ75976.1 - 2.2e-09 36.7 0.0 2.8e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AJZ75976.1 - 6.4e-05 22.2 0.0 8.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 AJZ75976.1 - 0.00013 21.1 0.0 0.028 13.4 0.0 2.0 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 AJZ75976.1 - 0.0012 17.3 0.0 0.002 16.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AsnC_trans_reg PF01037.16 AJZ75977.1 - 4.8e-09 35.8 0.4 5.9e-09 35.5 0.3 1.2 1 1 0 1 1 1 1 AsnC family ACT_4 PF13291.1 AJZ75977.1 - 0.0057 16.9 1.3 0.0075 16.5 0.9 1.2 1 0 0 1 1 1 1 ACT domain FliS PF02561.9 AJZ75977.1 - 0.074 12.9 1.0 0.13 12.0 0.6 1.4 1 1 0 1 1 1 0 Flagellar protein FliS Spore_II_R PF09551.5 AJZ75977.1 - 0.17 11.8 0.7 0.29 11.1 0.5 1.4 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Cyclase PF04199.8 AJZ75978.1 - 1.6e-36 125.5 0.0 2e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase DUF3489 PF11994.3 AJZ75978.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Radical_SAM PF04055.16 AJZ75979.1 - 1.6e-09 38.1 0.0 2.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 AJZ75979.1 - 0.0017 18.4 0.1 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain DNA_RNApol_7kD PF03604.8 AJZ75979.1 - 0.077 12.4 3.2 1.7 8.1 0.1 3.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.1 AJZ75979.1 - 4.7 6.9 7.9 21 4.9 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DSPc PF00782.15 AJZ75980.1 - 3.9e-21 75.0 0.0 4.7e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AJZ75980.1 - 1.7e-10 40.6 0.0 2.5e-10 40.0 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AJZ75980.1 - 6.9e-07 29.4 0.0 1.7e-06 28.1 0.0 1.6 1 1 1 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 AJZ75980.1 - 0.00031 21.0 0.1 0.0013 19.0 0.0 1.9 1 1 2 3 3 3 1 Tyrosine phosphatase family CDKN3 PF05706.7 AJZ75980.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF3391 PF11871.3 AJZ75980.1 - 0.0091 16.2 0.0 0.014 15.6 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3391) Y_phosphatase2 PF03162.8 AJZ75980.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF442 PF04273.8 AJZ75980.1 - 0.094 12.5 0.0 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 Putative phosphatase (DUF442) SnoaL_2 PF12680.2 AJZ75981.1 - 1.7e-11 44.3 0.0 2e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.7 AJZ75981.1 - 7.1e-06 26.0 0.1 9.1e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain SnoaL PF07366.7 AJZ75981.1 - 8.2e-05 22.1 0.1 0.00016 21.2 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.1 AJZ75981.1 - 0.016 15.3 0.0 0.019 15.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) WI12 PF07107.6 AJZ75981.1 - 0.036 13.9 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Wound-induced protein WI12 RNA_pol_L_2 PF13656.1 AJZ75983.1 - 2.2e-17 62.2 0.1 2.6e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1351 PF07083.6 AJZ75983.1 - 0.042 13.4 0.1 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) TFIIS_C PF01096.13 AJZ75984.1 - 1.2e-20 72.8 4.9 1.2e-20 72.8 3.4 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.2 AJZ75984.1 - 2e-05 24.2 9.5 0.007 16.1 2.6 2.3 2 0 0 2 2 2 2 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 AJZ75984.1 - 0.0028 17.4 12.2 0.0034 17.1 0.5 3.1 2 1 1 3 3 3 1 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.11 AJZ75984.1 - 0.012 15.3 16.2 0.94 9.2 6.5 4.0 3 1 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-DNA_Pol PF08996.5 AJZ75984.1 - 0.021 14.2 0.3 0.021 14.2 0.2 1.9 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger Ribosomal_L37e PF01907.14 AJZ75984.1 - 0.031 14.0 7.1 0.85 9.4 1.5 3.1 3 0 0 3 3 3 0 Ribosomal protein L37e zinc_ribbon_4 PF13717.1 AJZ75984.1 - 0.043 13.5 16.4 0.046 13.4 0.7 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-GRF PF06839.7 AJZ75984.1 - 0.044 13.7 0.4 0.044 13.7 0.3 2.5 2 1 1 3 3 3 0 GRF zinc finger zinc_ribbon_5 PF13719.1 AJZ75984.1 - 0.061 12.9 1.2 0.061 12.9 0.9 4.1 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 AJZ75984.1 - 0.067 13.1 14.3 3.7 7.5 0.0 4.2 3 1 1 4 4 4 0 Zinc ribbon domain A2L_zn_ribbon PF08792.5 AJZ75984.1 - 0.072 12.5 14.7 3.2 7.3 0.3 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain DUF2082 PF09855.4 AJZ75984.1 - 0.092 12.6 0.6 0.092 12.6 0.4 3.9 3 1 1 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Terminase_GpA PF05876.7 AJZ75984.1 - 0.14 10.4 2.4 0.14 10.4 1.6 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Elf1 PF05129.8 AJZ75984.1 - 0.49 10.1 9.2 0.041 13.5 0.4 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Tnp_zf-ribbon_2 PF13842.1 AJZ75984.1 - 0.83 10.1 11.3 12 6.3 0.1 3.3 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon C1_2 PF03107.11 AJZ75984.1 - 0.86 9.7 0.2 0.86 9.7 0.1 3.1 4 0 0 4 4 3 0 C1 domain Baculo_LEF5_C PF11792.3 AJZ75984.1 - 1.3 8.5 12.8 0.11 11.9 1.2 3.5 3 1 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain UPF0547 PF10571.4 AJZ75984.1 - 2.8 7.7 12.5 18 5.1 0.1 4.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-CSL PF05207.8 AJZ75984.1 - 3.8 7.0 7.9 0.45 10.0 0.3 2.7 3 0 0 3 3 3 0 CSL zinc finger DNA_RNApol_7kD PF03604.8 AJZ75984.1 - 4.3 6.8 14.2 5.6 6.5 0.1 3.5 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_4 PF13894.1 AJZ75984.1 - 4.5 7.8 9.9 88 3.7 0.5 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-ZPR1 PF03367.8 AJZ75984.1 - 4.8 6.3 7.9 2.8 7.0 0.1 2.7 2 2 0 2 2 2 0 ZPR1 zinc-finger domain HypA PF01155.14 AJZ75984.1 - 4.9 6.8 9.0 24 4.6 5.2 2.4 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family PhnA_Zn_Ribbon PF08274.7 AJZ75984.1 - 5.3 6.9 10.9 19 5.1 0.1 3.7 4 0 0 4 4 4 0 PhnA Zinc-Ribbon zf-MYND PF01753.13 AJZ75984.1 - 6.2 6.7 12.8 0.8 9.6 0.8 2.4 2 0 0 2 2 2 0 MYND finger zinc_ribbon_2 PF13240.1 AJZ75984.1 - 7.3 6.2 19.5 13 5.4 0.1 4.0 3 1 0 3 3 3 0 zinc-ribbon domain PolC_DP2 PF03833.8 AJZ75984.1 - 7.5 4.0 8.7 2.9 5.4 0.7 2.0 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 zf-ribbon_3 PF13248.1 AJZ75984.1 - 8.4 5.7 17.3 18 4.6 0.4 4.1 3 1 1 4 4 4 0 zinc-ribbon domain zf-UBR PF02207.15 AJZ75984.1 - 9.9 5.9 12.6 8.9 6.1 1.0 3.0 2 1 1 3 3 3 0 Putative zinc finger in N-recognin (UBR box) PCNA_N PF00705.13 AJZ75985.1 - 8.1e-19 67.3 0.0 2.7e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 AJZ75985.1 - 1.4e-15 57.2 0.1 2.2e-14 53.4 0.0 2.4 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 AJZ75985.1 - 0.0044 16.1 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 Rad9 Ecm33 PF12454.3 AJZ75985.1 - 0.098 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein AA_kinase PF00696.23 AJZ75986.1 - 9.8e-53 179.1 0.2 2.2e-52 178.0 0.2 1.6 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 AJZ75986.1 - 2.1e-20 71.9 3.5 2.5e-13 49.3 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 AJZ75986.1 - 1.9e-18 65.5 0.4 1.2e-10 40.5 0.0 2.8 2 0 0 2 2 2 2 ACT domain DEK_C PF08766.6 AJZ75986.1 - 0.02 14.6 1.5 0.046 13.5 0.0 2.4 3 0 0 3 3 3 0 DEK C terminal domain TP_methylase PF00590.15 AJZ75988.1 - 2.2e-35 122.3 0.0 2.5e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2073 PF09846.4 AJZ75988.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) tRNA-synt_1b PF00579.20 AJZ75989.1 - 1.3e-39 136.0 0.0 1.6e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ABA_GPCR PF12430.3 AJZ75990.1 - 0.21 10.6 6.2 1.2 8.2 0.4 2.7 3 0 0 3 3 3 0 Abscisic acid G-protein coupled receptor DUF2189 PF09955.4 AJZ75990.1 - 5.1 7.0 11.6 0.077 12.9 1.5 2.2 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) DegT_DnrJ_EryC1 PF01041.12 AJZ75991.1 - 4.2e-113 378.0 0.0 5e-113 377.8 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 AJZ75991.1 - 3e-09 36.3 0.0 4.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AJZ75991.1 - 3.4e-08 32.1 0.4 5.4e-08 31.5 0.2 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 AJZ75991.1 - 3.5e-07 29.6 0.0 9.7e-07 28.2 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 AJZ75991.1 - 2.4e-06 26.5 0.3 3.5e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MtrA PF04208.9 AJZ75992.1 - 6e-23 81.1 0.3 6.8e-23 81.0 0.2 1.0 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit A dUTPase_2 PF08761.6 AJZ75993.1 - 1.4e-19 70.8 7.0 2.6e-15 56.8 0.1 2.0 1 1 1 2 2 2 2 dUTPase PRA-PH PF01503.12 AJZ75993.1 - 0.02 15.1 0.0 0.024 14.8 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF550 PF04447.7 AJZ75993.1 - 0.13 11.8 1.5 0.21 11.2 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF550) PfkB PF00294.19 AJZ75994.1 - 3.3e-21 75.7 0.1 6.3e-21 74.7 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 AJZ75994.1 - 8.5e-05 21.8 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 AJZ75994.1 - 0.049 12.9 0.7 1.4 8.0 0.1 2.5 2 1 0 2 2 2 0 Carbohydrate kinase LEA_2 PF03168.8 AJZ75995.1 - 0.00082 19.7 0.0 0.0018 18.6 0.0 1.7 1 1 0 1 1 1 1 Late embryogenesis abundant protein HTH_27 PF13463.1 AJZ75996.1 - 0.13 12.6 0.0 1.4 9.3 0.0 2.4 2 1 0 2 2 2 0 Winged helix DNA-binding domain Pro_isomerase PF00160.16 AJZ75998.1 - 2.7e-48 164.1 0.1 3.1e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HTH_23 PF13384.1 AJZ75999.1 - 0.00083 18.9 0.0 0.0026 17.3 0.0 1.9 1 1 0 1 1 1 1 Homeodomain-like domain TrmB PF01978.14 AJZ75999.1 - 0.033 13.9 0.1 0.063 13.0 0.0 1.6 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.1 AJZ75999.1 - 0.035 14.1 0.0 0.19 11.7 0.0 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain GntR PF00392.16 AJZ75999.1 - 0.042 13.2 0.1 0.074 12.4 0.1 1.6 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF87 PF01935.12 AJZ75999.1 - 0.044 13.6 0.2 0.048 13.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 HTH_IclR PF09339.5 AJZ75999.1 - 0.062 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain ATG16 PF08614.6 AJZ76000.1 - 0.0014 18.4 3.8 0.0017 18.2 2.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 AJZ76000.1 - 0.002 18.0 3.4 0.0036 17.2 1.4 1.9 1 1 1 2 2 2 1 bZIP transcription factor DUF1423 PF07227.6 AJZ76000.1 - 0.0031 16.2 0.8 0.0033 16.1 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1423) DUF641 PF04859.7 AJZ76000.1 - 0.008 15.9 1.7 0.013 15.2 1.1 1.4 1 1 0 1 1 1 1 Plant protein of unknown function (DUF641) DUF2730 PF10805.3 AJZ76000.1 - 0.013 15.2 1.6 0.013 15.2 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) FlxA PF14282.1 AJZ76000.1 - 0.014 15.2 1.2 0.019 14.8 0.8 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF3810 PF12725.2 AJZ76000.1 - 0.02 13.8 6.5 0.062 12.1 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF4071 PF13281.1 AJZ76000.1 - 0.021 13.6 0.3 0.024 13.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) TBPIP PF07106.8 AJZ76000.1 - 0.023 14.2 4.7 0.032 13.7 3.2 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bap31 PF05529.7 AJZ76000.1 - 0.054 12.9 2.8 0.076 12.4 2.0 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1192 PF06698.6 AJZ76000.1 - 0.055 13.2 9.0 1 9.2 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) Baculo_PEP_C PF04513.7 AJZ76000.1 - 0.13 12.0 2.2 0.22 11.3 1.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.6 AJZ76000.1 - 0.17 11.3 5.4 0.21 11.0 3.8 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 CheY-binding PF09078.6 AJZ76000.1 - 0.23 11.4 2.0 5.7 7.0 0.1 2.8 2 1 1 3 3 3 0 CheY binding Mito_fiss_reg PF05308.6 AJZ76000.1 - 0.28 10.5 3.0 0.38 10.0 2.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Pox_A_type_inc PF04508.7 AJZ76000.1 - 0.4 10.5 4.7 1.3 9.0 0.1 3.1 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat DUF4369 PF14289.1 AJZ76001.1 - 0.015 15.3 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) CBM_6 PF03422.10 AJZ76001.1 - 0.11 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) FMN_red PF03358.10 AJZ76002.1 - 3.1e-24 85.2 0.0 3.9e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 AJZ76002.1 - 3e-09 36.6 0.0 3.8e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold Nitroreductase PF00881.19 AJZ76003.1 - 1.5e-27 96.4 0.0 2.4e-27 95.7 0.0 1.3 1 1 0 1 1 1 1 Nitroreductase family CopD PF05425.8 AJZ76004.1 - 3.3e-14 52.9 2.7 3.3e-14 52.9 1.9 1.5 2 0 0 2 2 2 1 Copper resistance protein D DUF2269 PF10027.4 AJZ76004.1 - 4.8e-05 23.1 9.6 6e-05 22.8 6.7 1.1 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) DUF4149 PF13664.1 AJZ76004.1 - 0.012 15.6 4.4 0.012 15.6 3.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DUF989 PF06181.6 AJZ76004.1 - 0.073 12.1 2.7 0.11 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF989) Orbi_NS3 PF01616.11 AJZ76004.1 - 0.57 9.1 6.8 0.089 11.7 0.9 2.0 2 0 0 2 2 2 0 Orbivirus NS3 RTC PF01137.16 AJZ76005.1 - 7.4e-74 247.3 0.2 8.6e-74 247.1 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase CTP_transf_2 PF01467.21 AJZ76006.1 - 1.6e-19 70.4 0.1 2e-19 70.1 0.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Aminotran_5 PF00266.14 AJZ76007.1 - 4e-35 121.2 0.0 5.1e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AJZ76007.1 - 7.6e-07 27.7 0.1 1.3e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 AJZ76007.1 - 0.0013 17.9 0.0 0.003 16.7 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Lipoprotein_9 PF03180.9 AJZ76007.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 NLPA lipoprotein FKBP_C PF00254.23 AJZ76008.1 - 1e-13 51.0 1.4 7.4e-13 48.3 0.4 2.6 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pribosyltran_N PF13793.1 AJZ76009.1 - 6.3e-24 83.9 0.0 5.1e-23 81.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 AJZ76009.1 - 9.5e-16 57.6 0.6 1.7e-14 53.5 0.0 2.7 3 0 0 3 3 3 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 AJZ76009.1 - 4.5e-12 46.1 5.0 3e-11 43.4 0.6 2.6 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain UPRTase PF14681.1 AJZ76009.1 - 1.9e-05 23.9 0.0 4.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 AJZ76009.1 - 0.0041 16.4 0.0 0.0091 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase Asp_Glu_race PF01177.17 AJZ76009.1 - 0.007 16.2 0.0 0.016 15.1 0.0 1.7 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase MFS_1_like PF12832.2 AJZ76009.1 - 0.042 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 MFS_1 like family PRTase_3 PF15610.1 AJZ76009.1 - 0.11 11.4 0.0 0.44 9.4 0.0 1.9 2 0 0 2 2 2 0 PRTase ComF-like UPF0020 PF01170.13 AJZ76010.1 - 1.3e-22 80.2 0.0 2.3e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 AJZ76010.1 - 2.6e-13 50.0 0.0 4.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJZ76010.1 - 8.6e-10 38.3 0.3 1.4e-09 37.7 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 AJZ76010.1 - 1.1e-09 38.1 0.1 4.5e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 DNA methylase Cons_hypoth95 PF03602.10 AJZ76010.1 - 2.9e-06 26.8 0.0 4.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 AJZ76010.1 - 3.5e-06 27.5 0.0 7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AJZ76010.1 - 5e-05 22.7 0.0 8.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 AJZ76010.1 - 0.00031 21.0 0.0 0.00063 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 AJZ76010.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase PrmA PF06325.8 AJZ76010.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 AJZ76010.1 - 0.0024 17.4 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.10 AJZ76010.1 - 0.0054 16.2 0.0 0.0095 15.4 0.0 1.5 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Met_10 PF02475.11 AJZ76010.1 - 0.007 15.9 0.1 0.017 14.7 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein THUMP PF02926.12 AJZ76010.1 - 0.0099 15.7 0.1 0.039 13.8 0.0 2.2 3 1 0 3 3 2 1 THUMP domain Methyltransf_12 PF08242.7 AJZ76010.1 - 0.015 15.7 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 AJZ76010.1 - 0.044 13.0 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_5 PF01795.14 AJZ76010.1 - 0.053 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 MraW methylase family RrnaAD PF00398.15 AJZ76010.1 - 0.055 12.4 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 AJZ76010.1 - 0.078 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 AJZ76010.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lactamase_B_2 PF12706.2 AJZ76011.1 - 1.5e-22 80.1 0.0 2.6e-22 79.3 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AJZ76011.1 - 6e-08 32.5 0.0 3.5e-07 30.0 0.0 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 AJZ76011.1 - 0.00092 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease SIR2 PF02146.12 AJZ76012.1 - 2.5e-53 180.4 0.0 3e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 AJZ76012.1 - 0.064 13.0 0.0 13 5.5 0.0 2.5 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain RNA_binding PF01877.12 AJZ76013.1 - 9.1e-17 61.1 0.0 2.5e-16 59.7 0.0 1.6 1 1 0 1 1 1 1 RNA binding DUF2102 PF09875.4 AJZ76013.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) AAA_18 PF13238.1 AJZ76014.1 - 3e-13 50.1 0.0 3.8e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AJZ76014.1 - 3.3e-11 44.0 0.0 4.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 AJZ76014.1 - 5.7e-05 23.0 0.1 7.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 AJZ76014.1 - 9e-05 22.3 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AJZ76014.1 - 0.0009 18.8 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 AJZ76014.1 - 0.0016 18.1 0.1 0.0037 16.9 0.1 1.7 1 1 1 2 2 2 1 Adenylylsulphate kinase KTI12 PF08433.5 AJZ76014.1 - 0.0023 17.1 0.1 0.0036 16.5 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 AJZ76014.1 - 0.0039 17.1 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AJZ76014.1 - 0.0052 16.9 0.2 0.012 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 AJZ76014.1 - 0.0059 16.7 0.2 0.011 15.9 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 AJZ76014.1 - 0.0065 15.3 0.0 0.0095 14.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ArgK PF03308.11 AJZ76014.1 - 0.0086 14.8 1.1 0.014 14.2 0.0 1.7 2 0 0 2 2 2 1 ArgK protein NTPase_1 PF03266.10 AJZ76014.1 - 0.0095 15.6 1.3 0.23 11.1 0.1 2.2 1 1 1 2 2 2 1 NTPase AAA_14 PF13173.1 AJZ76014.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AJZ76014.1 - 0.025 14.5 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CoaE PF01121.15 AJZ76014.1 - 0.032 13.6 0.1 0.064 12.6 0.0 1.6 2 1 0 2 2 2 0 Dephospho-CoA kinase Hpr_kinase_C PF07475.7 AJZ76014.1 - 0.043 13.1 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 AJZ76014.1 - 0.044 12.8 1.1 0.08 12.0 0.7 1.7 1 1 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 AJZ76014.1 - 0.056 12.8 0.6 0.65 9.3 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AJZ76014.1 - 0.088 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 AJZ76014.1 - 0.1 12.3 0.6 0.34 10.6 0.1 1.9 2 0 0 2 2 2 0 Part of AAA domain ABC_tran PF00005.22 AJZ76014.1 - 0.13 12.5 0.8 0.19 11.9 0.5 1.5 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 AJZ76014.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase LigT_PEase PF02834.11 AJZ76015.1 - 4.4e-24 84.2 0.0 1.1e-12 47.6 0.0 2.0 2 0 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.1 AJZ76015.1 - 1.7e-11 44.1 0.0 1.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.4 AJZ76015.1 - 2.1e-11 43.9 0.0 3.4e-11 43.2 0.0 1.3 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain tRNA_NucTransf2 PF09249.6 AJZ76016.1 - 7.7e-39 132.1 0.1 1.5e-38 131.1 0.1 1.5 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain NTP_transf_2 PF01909.18 AJZ76016.1 - 9.5e-10 38.6 0.0 2.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 AJZ76016.1 - 0.07 13.1 0.1 0.65 10.0 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase beta palm RIO1 PF01163.17 AJZ76017.1 - 0.00049 19.4 0.0 0.00075 18.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 AJZ76017.1 - 0.0013 17.9 0.1 0.0028 16.8 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 AJZ76017.1 - 0.0075 15.8 0.0 0.27 10.7 0.0 2.4 3 0 0 3 3 3 1 Choline/ethanolamine kinase APH PF01636.18 AJZ76017.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 AJZ76017.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HhH-GPD PF00730.20 AJZ76018.1 - 1.8e-20 73.2 0.0 2.5e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein A2M_N PF01835.14 AJZ76019.1 - 4.7e-09 36.3 0.0 2.5e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 MG2 domain YbbR PF07949.7 AJZ76019.1 - 0.0083 16.2 3.2 0.011 15.8 0.5 2.4 2 1 0 2 2 2 1 YbbR-like protein FlgD_ig PF13860.1 AJZ76019.1 - 0.018 14.7 0.5 0.54 10.0 0.1 2.5 2 0 0 2 2 2 0 FlgD Ig-like domain Big_3_4 PF13754.1 AJZ76019.1 - 2.2 8.6 5.9 1.1 9.5 0.2 2.8 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Ku_C PF03730.9 AJZ76020.1 - 0.083 13.4 0.3 0.089 13.3 0.2 1.1 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm zf-C2H2_6 PF13912.1 AJZ76020.1 - 0.17 11.8 0.8 5.9 6.9 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Pyr_redox_2 PF07992.9 AJZ76021.1 - 1.6e-22 80.3 0.0 2.3e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AJZ76021.1 - 2.9e-07 30.7 0.1 0.06 13.7 0.0 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AJZ76021.1 - 1.5e-05 24.0 0.0 0.1 11.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AJZ76021.1 - 9.7e-05 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AJZ76021.1 - 0.00043 20.3 0.0 1.9 8.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AJZ76021.1 - 0.0027 17.4 0.0 0.68 9.6 0.0 3.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 AJZ76021.1 - 0.026 13.3 0.0 0.099 11.4 0.0 2.0 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 AJZ76021.1 - 0.029 13.2 0.0 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 AJZ76021.1 - 0.05 12.0 0.1 2.4 6.5 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.9 AJZ76021.1 - 0.12 10.9 0.0 0.26 9.8 0.0 1.6 1 0 0 1 1 1 0 Tryptophan halogenase adh_short PF00106.20 AJZ76022.1 - 1.8e-37 128.7 0.1 2.5e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AJZ76022.1 - 8e-18 65.0 0.8 1.1e-17 64.6 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AJZ76022.1 - 1.2e-13 51.0 0.1 1.7e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AJZ76022.1 - 9e-05 22.5 2.5 0.00085 19.3 1.7 2.0 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 AJZ76022.1 - 0.0004 20.1 1.9 0.00079 19.1 0.7 2.0 2 1 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 AJZ76022.1 - 0.00058 19.3 0.1 0.0023 17.4 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 AJZ76022.1 - 0.0021 17.2 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 AJZ76022.1 - 0.062 12.3 0.8 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Wax2_C PF12076.3 AJZ76022.1 - 0.12 12.0 0.1 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain zf-AN1 PF01428.11 AJZ76023.1 - 6.9e-13 48.2 6.8 9.6e-13 47.7 4.7 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger UPF1_Zn_bind PF09416.5 AJZ76023.1 - 0.058 12.9 1.9 0.059 12.9 1.3 1.2 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) zf-BED PF02892.10 AJZ76023.1 - 0.21 11.3 8.2 1.4 8.7 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger IBR PF01485.16 AJZ76023.1 - 0.65 9.9 9.3 0.24 11.2 2.2 2.2 1 1 1 2 2 2 0 IBR domain RecR PF02132.10 AJZ76023.1 - 0.88 9.0 5.2 1.5 8.2 3.6 1.4 1 0 0 1 1 1 0 RecR protein PyrI_C PF02748.10 AJZ76023.1 - 3.6 7.0 8.2 4.2 6.8 0.3 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-FCS PF06467.9 AJZ76023.1 - 4 7.1 7.7 53 3.5 1.4 2.4 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Abi PF02517.11 AJZ76024.1 - 0.11 12.6 5.9 0.14 12.3 4.1 1.1 1 0 0 1 1 1 0 CAAX protease self-immunity YfzA PF14118.1 AJZ76024.1 - 0.35 11.0 2.9 0.53 10.4 2.0 1.3 1 0 0 1 1 1 0 YfzA-like protein ICMT PF04140.9 AJZ76024.1 - 1.3 9.2 5.5 1.8 8.8 2.9 1.7 1 1 1 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Meckelin PF09773.4 AJZ76024.1 - 1.4 6.5 4.2 1.5 6.4 2.9 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF2474 PF10617.4 AJZ76024.1 - 2.1 8.0 6.4 0.19 11.3 0.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2474) DUF760 PF05542.6 AJZ76025.1 - 0.014 15.5 0.1 0.034 14.3 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF760) Rhabdo_M1 PF03342.8 AJZ76025.1 - 0.081 12.0 1.0 0.14 11.3 0.5 1.4 1 1 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Gln-synt_C PF00120.19 AJZ76026.1 - 8.4e-90 300.4 0.0 1.1e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 AJZ76026.1 - 1.9e-23 81.8 0.1 4e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain TMEM238 PF15125.1 AJZ76027.1 - 0.019 14.8 1.4 0.033 14.1 1.0 1.4 1 0 0 1 1 1 0 TMEM238 protein family 7TMR-DISM_7TM PF07695.6 AJZ76027.1 - 0.074 12.7 8.6 0.084 12.5 6.0 1.0 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF3792 PF12670.2 AJZ76027.1 - 0.077 12.8 9.5 0.1 12.4 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) DUF1212 PF06738.7 AJZ76027.1 - 0.087 12.2 3.3 0.1 12.0 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) DUF3899 PF13038.1 AJZ76027.1 - 0.092 12.9 6.9 0.19 11.8 4.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) DUF1145 PF06611.7 AJZ76027.1 - 0.11 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1145) DUF2910 PF11139.3 AJZ76027.1 - 0.11 11.5 2.3 0.18 10.9 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2910) 5TM-5TMR_LYT PF07694.7 AJZ76027.1 - 0.21 10.8 6.8 0.32 10.3 4.7 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF2985 PF11204.3 AJZ76027.1 - 0.29 10.8 2.4 1.1 9.0 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) DUF308 PF03729.8 AJZ76027.1 - 3.5 7.7 13.1 8 6.5 0.8 2.3 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) SHMT PF00464.14 AJZ76028.1 - 3.1e-77 259.6 0.1 4.2e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 AJZ76028.1 - 1e-08 34.5 0.1 5.3e-08 32.1 0.1 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AJZ76028.1 - 1.6e-07 30.7 0.1 2.2e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.8 AJZ76028.1 - 7.7e-05 21.5 0.0 0.00014 20.7 0.0 1.4 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Aminotran_5 PF00266.14 AJZ76028.1 - 0.00021 20.1 0.2 0.00048 18.9 0.1 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.14 AJZ76028.1 - 0.014 13.9 0.0 0.023 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain PolC_DP2 PF03833.8 AJZ76029.1 - 4.5e-264 878.3 0.1 5e-263 874.9 0.1 2.0 1 1 0 1 1 1 1 DNA polymerase II large subunit DP2 DSX_dimer PF08828.5 AJZ76029.1 - 0.011 15.2 1.2 0.021 14.3 0.2 2.0 2 0 0 2 2 2 0 Doublesex dimerisation domain PcrB PF01884.12 AJZ76030.1 - 4.5e-68 228.9 0.3 5.9e-68 228.5 0.2 1.0 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.16 AJZ76030.1 - 2.6e-08 33.4 0.1 3.5e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein IMPDH PF00478.20 AJZ76030.1 - 2e-05 23.6 0.3 7.2e-05 21.8 0.2 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.15 AJZ76030.1 - 0.00045 18.8 1.9 0.0025 16.3 0.1 2.4 2 1 1 3 3 3 1 Tryptophan synthase alpha chain DHO_dh PF01180.16 AJZ76030.1 - 0.0015 17.5 0.6 0.0032 16.4 0.1 1.7 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.9 AJZ76030.1 - 0.0023 17.0 0.5 0.9 8.5 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IGPS PF00218.16 AJZ76030.1 - 0.0077 15.3 0.9 0.27 10.2 0.0 2.5 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase Ribul_P_3_epim PF00834.14 AJZ76030.1 - 0.0085 15.2 0.2 0.024 13.7 0.0 1.7 2 0 0 2 2 2 1 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.12 AJZ76030.1 - 0.021 13.9 0.1 0.09 11.8 0.0 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI NanE PF04131.9 AJZ76030.1 - 0.031 13.2 0.4 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 AJZ76030.1 - 0.11 11.6 6.1 0.36 9.9 0.5 2.6 2 1 1 3 3 3 0 Nitronate monooxygenase DS PF01916.12 AJZ76030.1 - 0.12 11.5 0.7 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 Deoxyhypusine synthase TrmB PF01978.14 AJZ76032.1 - 1.5e-05 24.6 0.0 2.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.1 AJZ76032.1 - 0.00052 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.17 AJZ76032.1 - 0.0068 16.0 0.3 0.013 15.2 0.2 1.4 1 0 0 1 1 1 1 MarR family DUF3116 PF11313.3 AJZ76032.1 - 0.016 14.7 0.1 0.034 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) HTH_45 PF14947.1 AJZ76032.1 - 0.026 14.3 0.1 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix Penicillinase_R PF03965.11 AJZ76032.1 - 0.069 13.2 0.9 0.099 12.7 0.0 1.7 2 0 0 2 2 2 0 Penicillinase repressor MarR_2 PF12802.2 AJZ76032.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 MarR family Crp PF00325.15 AJZ76032.1 - 0.26 10.8 2.1 0.62 9.5 0.5 2.2 1 1 1 2 2 2 0 Bacterial regulatory proteins, crp family DUF4463 PF14703.1 AJZ76032.1 - 0.91 10.0 3.5 1.3 9.5 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4463) Antitoxin-MazE PF04014.13 AJZ76033.1 - 1.3e-07 31.1 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Antidote-toxin recognition MazE eIF-1a PF01176.14 AJZ76033.1 - 0.0037 16.6 0.0 0.0047 16.3 0.0 1.3 1 1 0 1 1 1 1 Translation initiation factor 1A / IF-1 CDC48_N PF02359.13 AJZ76033.1 - 0.098 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain DUF1905 PF08922.6 AJZ76033.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) Penicillinase_R PF03965.11 AJZ76034.1 - 0.0044 17.1 0.0 0.0057 16.7 0.0 1.2 1 0 0 1 1 1 1 Penicillinase repressor PqqD PF05402.7 AJZ76034.1 - 0.026 14.5 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Cdc6_C PF09079.6 AJZ76035.1 - 7.6e-19 67.2 1.1 1.7e-18 66.1 0.1 2.0 2 0 0 2 2 2 1 CDC6, C terminal AAA_22 PF13401.1 AJZ76035.1 - 2.9e-14 53.3 0.5 1e-13 51.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AJZ76035.1 - 1.8e-12 47.6 0.5 2e-11 44.2 0.0 2.7 2 2 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 AJZ76035.1 - 4.9e-12 46.1 0.7 2e-11 44.2 0.2 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AJZ76035.1 - 5.2e-08 32.8 4.2 2e-07 30.9 1.8 2.5 1 1 1 2 2 2 1 Archaeal ATPase NACHT PF05729.7 AJZ76035.1 - 9.2e-08 31.9 0.1 2.7e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 AJZ76035.1 - 3.9e-06 25.9 0.1 1.7e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.4 AJZ76035.1 - 4e-06 26.0 0.0 5.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 AJZ76035.1 - 0.00012 21.2 0.5 0.11 11.4 0.0 2.4 1 1 0 2 2 2 2 KAP family P-loop domain AAA_32 PF13654.1 AJZ76035.1 - 0.00046 18.9 1.6 0.068 11.8 0.0 2.5 3 0 0 3 3 3 2 AAA domain DUF815 PF05673.8 AJZ76035.1 - 0.00064 18.7 0.3 0.0027 16.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 AJZ76035.1 - 0.00081 19.1 0.3 0.0077 15.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 AJZ76035.1 - 0.0011 17.9 0.2 0.0038 16.1 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.17 AJZ76035.1 - 0.0014 18.7 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 AJZ76035.1 - 0.0018 17.9 0.0 0.0074 16.0 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain PIF1 PF05970.9 AJZ76035.1 - 0.002 17.1 0.0 0.0044 16.0 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase KaiC PF06745.8 AJZ76035.1 - 0.0021 17.2 0.7 0.21 10.6 0.0 3.3 2 1 1 3 3 3 1 KaiC Sigma54_activat PF00158.21 AJZ76035.1 - 0.0039 16.6 0.0 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain TrwB_AAD_bind PF10412.4 AJZ76035.1 - 0.0044 15.7 0.1 0.018 13.7 0.0 1.9 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 AJZ76035.1 - 0.0051 16.4 0.1 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AJZ76035.1 - 0.01 14.9 0.0 0.09 11.8 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 AJZ76035.1 - 0.012 15.2 0.3 0.22 11.2 0.1 2.4 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.16 AJZ76035.1 - 0.013 14.6 0.0 0.042 13.0 0.0 1.8 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 AJZ76035.1 - 0.017 14.5 0.3 3.6 6.9 0.0 2.7 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_3 PF07726.6 AJZ76035.1 - 0.023 14.3 0.1 0.52 9.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 AJZ76035.1 - 0.025 14.1 0.2 3.9 7.0 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_11 PF13086.1 AJZ76035.1 - 0.027 14.0 3.2 0.07 12.6 2.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AJZ76035.1 - 0.036 13.4 0.2 0.16 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 AJZ76035.1 - 0.043 13.7 0.5 0.17 11.8 0.3 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase Phage-MuB_C PF09077.6 AJZ76035.1 - 0.052 13.2 1.0 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 Mu B transposition protein, C terminal Mg_chelatase_2 PF13335.1 AJZ76035.1 - 0.068 13.5 3.1 0.16 12.4 0.5 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI UvrD-helicase PF00580.16 AJZ76035.1 - 0.081 12.2 2.0 0.19 10.9 0.0 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_17 PF13207.1 AJZ76035.1 - 0.12 13.2 1.7 0.61 10.9 1.2 2.3 1 1 0 1 1 1 0 AAA domain DNA_pol_E_B PF04042.11 AJZ76036.1 - 2.1e-23 82.6 0.0 4.2e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.2 AJZ76036.1 - 9e-08 32.1 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AJZ76036.1 - 1.6e-05 24.4 0.3 3.3e-05 23.3 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase tRNA_anti-codon PF01336.20 AJZ76036.1 - 0.0064 16.3 0.2 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF95 PF01944.12 AJZ76037.1 - 8.7e-11 41.7 17.3 1.2e-10 41.3 12.0 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF95 Copper-bind PF00127.15 AJZ76038.1 - 0.001 19.2 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Big_3_4 PF13754.1 AJZ76038.1 - 0.87 9.9 0.1 0.87 9.9 0.0 3.5 3 1 1 4 4 4 0 Bacterial Ig-like domain (group 3) TP_methylase PF00590.15 AJZ76039.1 - 1.4e-31 109.8 0.0 1.6e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DAGK_cat PF00781.19 AJZ76039.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain GcpE PF04551.9 AJZ76039.1 - 0.016 14.0 0.1 0.021 13.6 0.1 1.1 1 0 0 1 1 1 0 GcpE protein DoxX PF07681.7 AJZ76041.1 - 4.3e-15 55.8 6.7 6.4e-15 55.3 4.7 1.3 1 0 0 1 1 1 1 DoxX DoxD PF04173.8 AJZ76041.1 - 4.7e-07 29.6 1.3 8.3e-06 25.5 0.5 2.0 2 0 0 2 2 2 1 TQO small subunit DoxD DoxX_2 PF13564.1 AJZ76041.1 - 5.2e-07 29.5 4.8 6.6e-07 29.2 3.3 1.3 1 0 0 1 1 1 1 DoxX-like family Peptidase_M24 PF00557.19 AJZ76042.1 - 2.8e-53 180.5 0.0 3.6e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 AJZ76042.1 - 1.3e-12 48.3 0.0 2.3e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain PGBA_N PF15436.1 AJZ76042.1 - 0.016 14.4 0.0 0.058 12.6 0.0 1.9 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA N-terminal ThiI PF02568.9 AJZ76043.1 - 1.5e-13 50.6 0.0 3.7e-13 49.3 0.0 1.6 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 AJZ76043.1 - 2.4e-09 36.2 0.1 1e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 tRNA methyl transferase DUF814 PF05670.8 AJZ76043.1 - 5.6e-07 29.3 0.0 1.5e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF814) Asn_synthase PF00733.16 AJZ76043.1 - 0.00017 21.1 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AJZ76043.1 - 0.0039 16.4 0.1 0.0076 15.5 0.1 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC DUF552 PF04472.7 AJZ76044.1 - 1.2e-15 57.1 0.2 1.4e-15 56.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF552) PYNP_C PF07831.8 AJZ76045.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF1857 PF08982.6 AJZ76046.1 - 2.2e-07 30.6 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Polyketide_cyc2 PF10604.4 AJZ76046.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Pirin PF02678.11 AJZ76047.1 - 2.8e-32 110.7 1.2 4.6e-32 110.0 0.8 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 AJZ76047.1 - 1e-05 24.9 2.7 4.4e-05 22.8 0.1 2.7 3 0 0 3 3 3 1 Cupin domain TAF4 PF05236.9 AJZ76047.1 - 0.0087 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Pox_A31 PF05771.6 AJZ76047.1 - 0.017 14.9 0.3 6.4 6.6 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A31 protein Peptidase_M48 PF01435.13 AJZ76048.1 - 7.6e-40 136.8 1.2 1.1e-39 136.2 0.0 1.7 1 1 1 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.6 AJZ76048.1 - 2.8e-05 23.2 0.2 5.8e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF955 PF06114.8 AJZ76048.1 - 0.015 15.0 0.1 0.037 13.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF955) DUF2201_N PF13203.1 AJZ76048.1 - 0.05 12.7 0.1 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain ENOD93 PF03386.9 AJZ76048.1 - 0.13 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein PAP2 PF01569.16 AJZ76048.1 - 1.7 8.3 7.5 6.5 6.4 5.2 2.0 1 1 0 1 1 1 0 PAP2 superfamily DUF1469 PF07332.6 AJZ76048.1 - 3.5 7.3 7.2 6.5 6.5 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Beta-Casp PF10996.3 AJZ76049.1 - 1.2e-31 109.2 0.0 2.7e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 AJZ76049.1 - 2.9e-19 69.4 0.1 7.1e-19 68.2 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 AJZ76049.1 - 1e-12 47.6 0.0 7.6e-12 44.8 0.0 2.3 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 AJZ76049.1 - 4.6e-10 39.3 0.1 1.2e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AJZ76049.1 - 0.037 13.7 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Metallophos_2 PF12850.2 AJZ76051.1 - 6.9e-14 51.9 0.1 2.4e-13 50.2 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AJZ76051.1 - 8.9e-09 35.0 0.1 2.5e-07 30.3 0.1 2.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short PF00106.20 AJZ76052.1 - 2.1e-09 37.5 0.0 0.00062 19.7 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase RmlD_sub_bind PF04321.12 AJZ76052.1 - 6.1e-06 25.3 0.1 0.00012 21.0 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short_C2 PF13561.1 AJZ76052.1 - 7.8e-06 25.8 0.0 6.8e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 AJZ76052.1 - 0.0013 18.7 0.0 0.0018 18.3 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 AJZ76052.1 - 0.023 13.8 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 AJZ76052.1 - 0.083 12.6 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Hemerythrin PF01814.18 AJZ76053.1 - 2.3e-10 40.7 0.8 4.2e-10 39.9 0.1 1.7 1 1 1 2 2 2 1 Hemerythrin HHE cation binding domain APC8 PF04049.8 AJZ76053.1 - 0.025 14.3 0.4 0.15 11.8 0.2 2.1 1 1 1 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 DUF445 PF04286.7 AJZ76053.1 - 0.044 13.3 1.0 0.047 13.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Inositol_P PF00459.20 AJZ76054.1 - 4.9e-47 160.4 0.1 5.7e-47 160.2 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 AJZ76054.1 - 0.00057 18.8 0.1 0.001 17.9 0.1 1.4 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase RimK PF08443.6 AJZ76054.1 - 0.048 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain adh_short PF00106.20 AJZ76056.1 - 3.3e-30 105.1 0.0 4.1e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AJZ76056.1 - 3.4e-30 105.6 0.1 4.1e-30 105.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AJZ76056.1 - 3.6e-08 33.2 0.0 5.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AJZ76056.1 - 0.0002 20.8 1.1 0.0025 17.3 0.8 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 AJZ76056.1 - 0.014 15.1 0.7 0.028 14.2 0.5 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 AJZ76056.1 - 0.033 14.2 0.1 0.067 13.1 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding F420_oxidored PF03807.12 AJZ76056.1 - 0.036 14.4 0.9 0.15 12.5 0.3 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TRCF PF03461.10 AJZ76056.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 TRCF domain THF_DHG_CYH_C PF02882.14 AJZ76056.1 - 0.094 11.7 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TFIIB PF00382.14 AJZ76057.1 - 4e-35 119.4 2.7 5.6e-17 61.3 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJZ76057.1 - 5.1e-08 32.1 1.4 9.2e-08 31.2 1.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Sigma70_r4 PF04545.11 AJZ76057.1 - 0.00018 20.7 0.0 0.0044 16.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 Cyclin_C PF02984.14 AJZ76057.1 - 0.00028 20.7 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain HTH_11 PF08279.7 AJZ76057.1 - 0.0015 18.1 0.8 0.078 12.6 0.0 2.9 3 0 0 3 3 3 1 HTH domain Cyclin_N PF00134.18 AJZ76057.1 - 0.0038 16.7 0.1 0.063 12.8 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain HTH_23 PF13384.1 AJZ76057.1 - 0.005 16.4 0.2 0.027 14.1 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 AJZ76057.1 - 0.025 14.0 0.2 0.089 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 AJZ76057.1 - 0.026 14.0 0.0 0.23 11.0 0.0 2.5 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain RRN7 PF11781.3 AJZ76057.1 - 0.062 12.8 0.9 0.14 11.7 0.6 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 HTH_3 PF01381.17 AJZ76057.1 - 0.096 12.5 0.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix OrfB_Zn_ribbon PF07282.6 AJZ76057.1 - 0.26 10.9 1.1 0.58 9.8 0.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Snf7 PF03357.16 AJZ76058.1 - 0.0017 17.8 3.7 0.0027 17.1 2.6 1.4 1 1 0 1 1 1 1 Snf7 TelA PF05816.6 AJZ76058.1 - 0.0062 15.2 0.3 0.0085 14.8 0.2 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Viral_P18 PF04521.8 AJZ76058.1 - 0.013 14.8 1.4 0.024 14.0 1.0 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DivIVA PF05103.8 AJZ76058.1 - 0.015 15.3 0.8 0.12 12.4 0.3 2.1 2 0 0 2 2 2 0 DivIVA protein MotA_ExbB PF01618.11 AJZ76058.1 - 0.018 14.7 0.1 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF3251 PF11622.3 AJZ76058.1 - 0.018 14.4 0.8 0.036 13.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) DUF3958 PF13125.1 AJZ76058.1 - 0.018 14.9 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Phasin PF05597.6 AJZ76058.1 - 0.045 13.5 0.7 0.11 12.2 0.3 1.7 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NAD_Gly3P_dh_C PF07479.9 AJZ76058.1 - 0.057 13.1 0.6 0.087 12.5 0.4 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus LOH1CR12 PF10158.4 AJZ76058.1 - 0.057 13.2 0.5 0.15 11.8 0.3 1.7 1 1 0 1 1 1 0 Tumour suppressor protein Nup54 PF13874.1 AJZ76058.1 - 0.091 12.4 1.3 0.15 11.6 0.9 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 CENP-H PF05837.7 AJZ76058.1 - 0.23 11.6 1.8 0.47 10.6 1.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF1664 PF07889.7 AJZ76059.1 - 0.00011 22.0 2.3 0.00016 21.4 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Spc7 PF08317.6 AJZ76059.1 - 0.00079 18.1 4.6 0.00079 18.1 3.2 1.4 1 1 0 1 1 1 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 AJZ76059.1 - 0.0026 17.0 0.3 0.0032 16.6 0.2 1.0 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 AJZ76059.1 - 0.0046 16.8 8.3 0.025 14.4 5.8 2.0 1 1 0 1 1 1 1 Tropomyosin like DUF4200 PF13863.1 AJZ76059.1 - 0.022 14.7 3.7 0.022 14.7 2.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3053 PF11254.3 AJZ76059.1 - 0.023 13.9 0.1 0.6 9.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) Syntaxin PF00804.20 AJZ76059.1 - 0.047 13.8 6.4 0.18 11.9 4.5 2.1 1 1 0 1 1 1 0 Syntaxin DUF3450 PF11932.3 AJZ76059.1 - 0.083 12.1 1.9 0.11 11.7 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Syntaxin_2 PF14523.1 AJZ76059.1 - 0.11 12.5 4.5 9.9 6.2 2.7 2.4 1 1 0 1 1 1 0 Syntaxin-like protein AAA_13 PF13166.1 AJZ76059.1 - 0.13 10.6 6.1 0.15 10.4 4.2 1.1 1 0 0 1 1 1 0 AAA domain AKNA PF12443.3 AJZ76059.1 - 0.15 12.0 1.2 0.37 10.8 0.6 1.9 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF948 PF06103.6 AJZ76059.1 - 0.38 10.6 1.7 6.7 6.6 0.3 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 AJZ76059.1 - 0.38 10.4 6.2 0.37 10.5 3.3 1.8 1 1 1 2 2 2 0 Laminin Domain II Mod_r PF07200.8 AJZ76059.1 - 0.45 10.4 4.4 0.63 9.9 1.3 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.7 AJZ76059.1 - 0.59 10.4 3.9 3.7 7.8 1.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 AJZ76059.1 - 0.7 10.2 8.9 0.21 11.9 2.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 AJZ76059.1 - 0.8 9.2 7.0 1.2 8.6 4.9 1.4 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 AJZ76059.1 - 1.3 7.8 5.9 2.1 7.2 4.1 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 AJZ76059.1 - 1.9 8.1 6.8 4.9 6.7 4.7 1.8 1 1 0 1 1 1 0 Mnd1 family APG6 PF04111.7 AJZ76059.1 - 2.5 7.0 6.0 3.9 6.4 4.2 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Prefoldin PF02996.12 AJZ76059.1 - 7.3 6.2 8.7 2.3 7.9 0.7 2.8 2 1 1 3 3 3 0 Prefoldin subunit Osmo_CC PF08946.5 AJZ76059.1 - 9.7 6.3 10.9 1.8 8.6 0.2 3.9 2 1 3 5 5 4 0 Osmosensory transporter coiled coil Imm16 PF15565.1 AJZ76060.1 - 0.011 15.6 0.3 0.034 14.0 0.2 1.8 1 0 0 1 1 1 0 Immunity protein 16 IncA PF04156.9 AJZ76060.1 - 0.019 14.5 0.1 0.019 14.5 0.1 3.6 2 1 1 3 3 3 0 IncA protein F_actin_bind PF08919.5 AJZ76060.1 - 0.031 13.9 0.9 0.36 10.5 0.0 3.2 3 2 0 3 3 3 0 F-actin binding CPSase_L_D3 PF02787.14 AJZ76060.1 - 0.067 12.9 3.2 0.9 9.3 0.3 3.5 3 1 0 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Rep_fac_C PF08542.6 AJZ76060.1 - 0.58 10.1 6.1 7.1 6.6 0.7 3.4 2 1 1 3 3 3 0 Replication factor C C-terminal domain DUF981 PF06168.6 AJZ76061.1 - 0.02 14.7 2.6 0.023 14.4 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF3021 PF11457.3 AJZ76061.1 - 0.28 11.0 2.3 0.33 10.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DUF2892 PF11127.3 AJZ76061.1 - 1.1 9.0 3.5 1.4 8.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) PsbT PF01405.12 AJZ76061.1 - 2.5 7.7 4.6 0.57 9.8 0.7 1.8 2 0 0 2 2 2 0 Photosystem II reaction centre T protein Tetraspannin PF00335.15 AJZ76061.1 - 4.2 6.5 5.2 5.1 6.3 3.6 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF2970 PF11174.3 AJZ76061.1 - 7.6 6.1 7.7 10 5.7 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Fer4_14 PF13394.1 AJZ76062.1 - 7.1e-15 55.0 0.4 1.4e-14 54.0 0.2 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AJZ76062.1 - 1.4e-13 51.1 0.5 3.7e-13 49.8 0.1 1.7 1 1 1 2 2 2 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 AJZ76062.1 - 5.2e-12 46.2 0.0 7.1e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily PGM_PMM_II PF02879.11 AJZ76062.1 - 0.057 13.7 0.0 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II GTP_cyclohydroI PF01227.17 AJZ76063.1 - 3.4e-63 212.1 0.0 3.8e-63 212.0 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 AJZ76063.1 - 0.004 17.0 0.0 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 QueF-like protein AAA_22 PF13401.1 AJZ76063.1 - 0.079 13.1 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain FeoB_C PF07664.7 AJZ76064.1 - 0.01 15.2 1.4 0.29 10.5 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus QueC PF06508.8 AJZ76065.1 - 3.3e-47 160.5 0.1 3.8e-47 160.2 0.1 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 AJZ76065.1 - 0.00037 20.0 0.0 0.00057 19.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GHMP_kinases_N PF00288.21 AJZ76066.1 - 4.4e-15 55.4 2.8 1.4e-14 53.9 2.0 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AJZ76066.1 - 6e-09 35.9 0.1 1.6e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal ATP_bind_1 PF03029.12 AJZ76067.1 - 4.6e-55 186.7 0.0 5.1e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 AJZ76067.1 - 0.00036 19.9 0.3 0.00044 19.6 0.2 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 AJZ76067.1 - 0.00099 19.9 0.1 0.002 18.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 AJZ76067.1 - 0.0018 17.3 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 AJZ76067.1 - 0.0019 17.3 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.2 AJZ76067.1 - 0.0046 16.4 0.1 0.023 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 AJZ76067.1 - 0.0069 15.1 0.0 0.014 14.1 0.0 1.5 1 0 0 1 1 1 1 ArgK protein SRP54 PF00448.17 AJZ76067.1 - 0.023 14.1 0.1 0.9 8.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 AJZ76067.1 - 0.025 14.7 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AJZ76067.1 - 0.031 14.5 0.0 0.081 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AJZ76067.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 AJZ76067.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 AJZ76067.1 - 0.092 11.5 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 AJZ76067.1 - 0.095 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AJZ76067.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain UPF0104 PF03706.8 AJZ76068.1 - 5.1e-21 75.2 19.3 8e-21 74.5 13.4 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) adh_short PF00106.20 AJZ76069.1 - 1.2e-39 135.9 0.0 1.4e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AJZ76069.1 - 2.6e-18 66.3 0.0 3.5e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AJZ76069.1 - 1.5e-15 57.5 0.1 1.9e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 AJZ76069.1 - 7.4e-08 31.8 0.0 1.5e-07 30.8 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 AJZ76069.1 - 3.5e-06 27.1 0.0 1.5e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 AJZ76069.1 - 0.00027 20.6 0.1 0.00061 19.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 AJZ76069.1 - 0.00092 18.8 0.1 0.0016 18.0 0.1 1.4 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.10 AJZ76069.1 - 0.0022 16.9 0.2 0.0028 16.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 AJZ76069.1 - 0.0069 15.8 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 AJZ76069.1 - 0.015 15.4 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 AJZ76069.1 - 0.03 13.3 0.1 0.056 12.5 0.1 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Wax2_C PF12076.3 AJZ76069.1 - 0.091 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain Ribosomal_L32p PF01783.18 AJZ76070.1 - 0.0063 16.6 0.2 0.77 9.9 0.0 2.3 2 0 0 2 2 2 1 Ribosomal L32p protein family PhosphMutase PF10143.4 AJZ76070.1 - 0.022 14.4 0.0 0.023 14.3 0.0 1.0 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase TF_Zn_Ribbon PF08271.7 AJZ76070.1 - 0.072 12.4 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 AJZ76070.1 - 0.1 12.5 0.2 10 6.1 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 AJZ76070.1 - 0.1 12.2 0.0 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 AJZ76070.1 - 0.15 11.8 0.8 1.3 8.8 0.6 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Rubredoxin PF00301.15 AJZ76070.1 - 0.35 10.7 1.8 8.3 6.3 0.0 2.4 2 1 1 3 3 3 0 Rubredoxin GATA PF00320.22 AJZ76070.1 - 0.77 9.1 0.0 0.77 9.1 0.0 2.3 3 0 0 3 3 3 0 GATA zinc finger Glyco_trans_1_3 PF13528.1 AJZ76071.1 - 1.4e-14 54.0 0.0 1.2e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 Tautomerase_2 PF14552.1 AJZ76072.1 - 0.024 14.6 0.6 0.11 12.5 0.1 2.2 2 0 0 2 2 2 0 Tautomerase enzyme PAPS_reduct PF01507.14 AJZ76073.1 - 7.3e-45 152.9 0.0 1e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3452 PF11934.3 AJZ76073.1 - 0.013 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF2624 PF11116.3 AJZ76073.1 - 0.019 15.4 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) SYF2 PF08231.7 AJZ76073.1 - 0.038 14.1 0.0 9.9 6.2 0.0 2.3 2 0 0 2 2 2 0 SYF2 splicing factor ATP-sulfurylase PF01747.12 AJZ76074.1 - 6.5e-84 280.5 0.0 8.4e-84 280.1 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 AJZ76074.1 - 3.2e-43 146.8 0.0 6.7e-43 145.8 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain DUF521 PF04412.8 AJZ76076.1 - 1.3e-102 343.3 0.0 2e-102 342.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.11 AJZ76077.1 - 1.4e-27 95.1 0.1 2e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF126 PEP-utilizers PF00391.18 AJZ76077.1 - 0.01 15.3 0.0 0.026 14.0 0.0 1.8 2 1 0 2 2 2 0 PEP-utilising enzyme, mobile domain DUF3945 PF13101.1 AJZ76077.1 - 0.046 13.0 0.1 3.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) AMMECR1 PF01871.12 AJZ76078.1 - 2.7e-57 192.6 0.0 3.2e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Mut7-C PF01927.11 AJZ76079.1 - 2.1e-35 121.8 0.1 2.3e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain SporV_AA PF12164.3 AJZ76079.1 - 0.018 14.9 0.7 0.03 14.2 0.5 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AA DUF4411 PF14367.1 AJZ76079.1 - 0.043 13.5 0.2 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) SUKH_5 PF14567.1 AJZ76079.1 - 0.09 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall zf-RanBP PF00641.13 AJZ76079.1 - 0.69 9.0 3.4 0.67 9.1 0.4 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others FbpA PF05833.6 AJZ76080.1 - 1.4e-50 172.1 1.5 1.9e-50 171.7 1.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 AJZ76080.1 - 1.7e-16 59.8 0.0 2.8e-15 55.9 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF814) DUF2136 PF09907.4 AJZ76080.1 - 0.044 13.8 0.3 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2136) Lge1 PF11488.3 AJZ76080.1 - 0.54 10.4 3.3 0.3 11.3 0.5 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF3236 PF11576.3 AJZ76080.1 - 0.89 8.9 5.1 0.12 11.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) Multi_Drug_Res PF00893.14 AJZ76081.1 - 0.0042 17.5 3.5 0.052 14.0 0.3 2.0 1 1 1 2 2 2 2 Small Multidrug Resistance protein Rab5ip PF07019.7 AJZ76081.1 - 0.0057 16.7 7.0 0.011 15.7 4.9 1.5 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) EamA PF00892.15 AJZ76081.1 - 0.026 14.5 2.7 0.035 14.1 1.9 1.2 1 0 0 1 1 1 0 EamA-like transporter family EmrE PF13536.1 AJZ76081.1 - 0.039 14.1 3.0 0.098 12.8 1.4 1.8 2 0 0 2 2 2 0 Multidrug resistance efflux transporter DUF1109 PF06532.6 AJZ76081.1 - 0.053 12.9 0.1 0.068 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1109) DUF202 PF02656.10 AJZ76081.1 - 4.4 7.6 8.4 89 3.4 5.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Methyltransf_18 PF12847.2 AJZ76082.1 - 7.5e-16 58.7 0.1 1e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJZ76082.1 - 7.9e-14 51.5 0.3 1.6e-13 50.5 0.1 1.4 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.14 AJZ76082.1 - 7.3e-11 41.9 0.3 9.2e-11 41.6 0.2 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 AJZ76082.1 - 1.4e-08 34.2 1.6 1.9e-08 33.8 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AJZ76082.1 - 2.7e-08 33.3 0.0 4.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AJZ76082.1 - 1.7e-07 31.3 0.0 3.3e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AJZ76082.1 - 1.9e-07 30.4 0.1 2.4e-07 30.0 0.1 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 AJZ76082.1 - 8e-07 28.3 0.1 1.5e-06 27.4 0.0 1.4 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_4 PF02390.12 AJZ76082.1 - 3.2e-06 26.3 0.0 6.4e-06 25.3 0.0 1.5 2 0 0 2 2 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 AJZ76082.1 - 8.2e-06 26.1 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 AJZ76082.1 - 9.1e-06 25.3 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 AJZ76082.1 - 9.7e-06 25.3 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.7 AJZ76082.1 - 1.8e-05 25.1 0.0 5.5e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJZ76082.1 - 4.1e-05 23.9 0.1 8.5e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 AJZ76082.1 - 0.00055 19.5 0.0 0.00087 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.1 AJZ76082.1 - 0.00065 20.5 0.0 0.00096 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 AJZ76082.1 - 0.00084 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 AviRa PF11599.3 AJZ76082.1 - 0.0019 17.2 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa DUF633 PF04816.7 AJZ76082.1 - 0.0031 16.8 0.2 0.0048 16.2 0.1 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF633) Nol1_Nop2_Fmu PF01189.12 AJZ76082.1 - 0.0055 16.1 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family CMAS PF02353.15 AJZ76082.1 - 0.0062 15.6 0.0 0.013 14.5 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.5 AJZ76082.1 - 0.014 14.8 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 AJZ76082.1 - 0.016 14.2 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Spermine_synth PF01564.12 AJZ76082.1 - 0.025 13.5 0.1 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase NAC PF01849.13 AJZ76082.1 - 0.038 13.5 0.2 0.57 9.7 0.0 2.6 3 0 0 3 3 3 0 NAC domain DOT1 PF08123.8 AJZ76082.1 - 0.049 12.9 0.0 0.08 12.2 0.0 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 DUF43 PF01861.11 AJZ76082.1 - 0.073 12.0 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_23 PF13489.1 AJZ76082.1 - 0.095 12.4 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.14 AJZ76082.1 - 0.096 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family FtsJ PF01728.14 AJZ76082.1 - 0.1 12.5 0.1 0.3 11.0 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase TP_methylase PF00590.15 AJZ76083.1 - 7.9e-50 169.4 0.0 8.9e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TP_methylase PF00590.15 AJZ76084.1 - 2.5e-43 148.2 0.1 3e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.16 AJZ76084.1 - 0.013 15.7 0.0 0.035 14.2 0.0 1.7 1 1 0 1 1 1 0 Radical SAM superfamily DUF694 PF05107.7 AJZ76087.1 - 0.0091 15.2 0.2 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF694) Snf7 PF03357.16 AJZ76087.1 - 0.013 14.9 8.2 0.038 13.3 5.7 1.8 1 1 0 1 1 1 0 Snf7 Baculo_PEP_C PF04513.7 AJZ76087.1 - 0.052 13.3 2.5 1.1 9.0 0.1 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc24 PF08286.6 AJZ76087.1 - 0.11 12.1 2.6 0.16 11.6 0.5 2.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 ALIX_LYPXL_bnd PF13949.1 AJZ76087.1 - 0.46 9.4 5.2 0.84 8.5 2.6 2.1 2 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV Prominin PF05478.6 AJZ76087.1 - 0.52 7.7 3.1 0.81 7.1 1.7 1.6 1 1 1 2 2 2 0 Prominin NPV_P10 PF05531.7 AJZ76087.1 - 0.99 9.6 3.6 15 5.9 0.5 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF745 PF05335.8 AJZ76087.1 - 4.3 6.8 8.8 5.6 6.4 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Asp_Glu_race PF01177.17 AJZ76088.1 - 2e-19 70.3 0.0 2.4e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Ribosomal_L23 PF00276.15 AJZ76088.1 - 0.041 13.8 2.4 0.05 13.5 0.3 2.1 2 0 0 2 2 2 0 Ribosomal protein L23 Laminin_G_3 PF13385.1 AJZ76089.1 - 5.4e-33 114.4 12.2 2e-17 63.8 0.1 6.8 6 2 0 6 6 6 3 Concanavalin A-like lectin/glucanases superfamily FpoO PF10621.4 AJZ76089.1 - 0.015 15.3 0.1 7 6.7 0.0 2.5 2 0 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO fn1 PF00039.13 AJZ76089.1 - 2.6 7.9 4.0 28 4.6 0.2 2.7 2 0 0 2 2 2 0 Fibronectin type I domain HHH_2 PF12826.2 AJZ76090.1 - 0.0033 17.2 0.9 15 5.5 0.0 7.5 2 1 0 1 1 1 1 Helix-hairpin-helix motif tRNA-synt_2b PF00587.20 AJZ76091.1 - 1.7e-45 154.6 0.0 3.2e-45 153.7 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AJZ76091.1 - 4.3e-14 52.2 0.3 1.9e-13 50.1 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain Zn-ribbon_8 PF09723.5 AJZ76091.1 - 0.047 13.6 0.2 2.2 8.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain AP_endonuc_2 PF01261.19 AJZ76092.1 - 2.8e-32 111.7 0.1 1.1e-31 109.8 0.1 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF4621 PF15414.1 AJZ76092.1 - 0.041 12.5 0.0 0.072 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) DNA_primase_lrg PF04104.9 AJZ76093.1 - 1.1e-25 90.4 0.1 2.2e-25 89.4 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DNA_primase_S PF01896.14 AJZ76094.1 - 1.6e-13 50.7 0.3 6.7e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit NRDD PF13597.1 AJZ76094.1 - 0.013 13.6 1.2 0.023 12.7 0.8 1.3 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase MutS_IV PF05190.13 AJZ76094.1 - 0.028 14.5 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 MutS family domain IV UPF0182 PF03699.8 AJZ76095.1 - 1.2e-30 106.1 11.9 3.5e-29 101.3 8.2 2.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0182) GATase PF00117.23 AJZ76096.1 - 9.7e-24 83.8 0.1 1.1e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AJZ76096.1 - 2.2e-11 43.6 0.0 4.2e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.14 AJZ76096.1 - 0.023 14.3 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 SNO glutamine amidotransferase family TPR_11 PF13414.1 AJZ76097.1 - 7.9e-20 70.2 3.9 1.3e-12 47.1 0.8 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AJZ76097.1 - 3.7e-14 51.6 8.8 2.2e-06 26.9 0.4 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 AJZ76097.1 - 1.7e-12 46.2 5.8 0.00039 20.1 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 AJZ76097.1 - 4.5e-09 35.7 6.0 0.00012 22.0 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ76097.1 - 5.8e-07 29.3 4.4 8.6e-05 22.3 0.2 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AJZ76097.1 - 1.7e-06 28.5 0.2 0.32 11.7 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ76097.1 - 3.1e-06 26.5 13.7 0.012 15.2 0.8 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 AJZ76097.1 - 1.7e-05 24.5 0.0 3.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ76097.1 - 4.3e-05 23.7 3.2 0.022 15.1 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AJZ76097.1 - 9.1e-05 22.7 0.0 0.18 12.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Peptidase_C39_2 PF13529.1 AJZ76097.1 - 0.00034 21.0 0.4 0.0042 17.4 0.0 2.6 2 1 0 2 2 2 1 Peptidase_C39 like family TPR_7 PF13176.1 AJZ76097.1 - 0.015 15.0 1.0 5.6 7.0 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Peptidase_C39 PF03412.10 AJZ76097.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase C39 family TPR_10 PF13374.1 AJZ76097.1 - 0.052 13.5 0.0 0.19 11.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Lipoprotein_3 PF00938.12 AJZ76097.1 - 0.11 12.2 1.3 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 Lipoprotein TPR_6 PF13174.1 AJZ76097.1 - 1.2 9.7 6.0 11 6.7 0.1 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Ribosomal_S6e PF01092.14 AJZ76098.1 - 3.3e-19 68.7 0.3 3.8e-19 68.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S6e GTP_EFTU PF00009.22 AJZ76099.1 - 1.9e-40 138.3 0.0 3e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 AJZ76099.1 - 5.2e-23 80.9 0.8 1.1e-22 79.8 0.1 1.9 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal MMR_HSR1 PF01926.18 AJZ76099.1 - 0.00036 20.4 0.0 0.00076 19.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 AJZ76099.1 - 0.00079 19.5 0.4 0.0035 17.4 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 NOB1_Zn_bind PF08772.6 AJZ76099.1 - 0.017 14.9 0.2 0.048 13.4 0.1 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like PhnA_Zn_Ribbon PF08274.7 AJZ76099.1 - 0.021 14.6 0.7 0.04 13.7 0.0 1.8 2 0 0 2 2 2 0 PhnA Zinc-Ribbon FeoB_N PF02421.13 AJZ76099.1 - 0.033 13.4 0.3 1.8 7.8 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B Zn_Tnp_IS1595 PF12760.2 AJZ76099.1 - 0.078 12.8 0.5 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 AJZ76099.1 - 0.08 12.7 0.8 0.14 11.9 0.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 AJZ76099.1 - 0.09 12.7 4.2 0.28 11.1 3.0 1.8 1 1 0 1 1 1 0 Zinc ribbon domain PduV-EutP PF10662.4 AJZ76099.1 - 0.13 11.7 0.8 1 8.8 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation zf-ribbon_3 PF13248.1 AJZ76099.1 - 3.4 6.9 6.5 9.3 5.6 4.6 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AJZ76099.1 - 7.2 6.2 8.2 18 4.9 5.7 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Fcf1 PF04900.7 AJZ76100.1 - 1.4e-10 41.1 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Fcf1 PIN_4 PF13638.1 AJZ76100.1 - 0.0069 16.4 0.4 0.0094 16.0 0.3 1.4 1 1 0 1 1 1 1 PIN domain PIN PF01850.16 AJZ76100.1 - 0.078 13.3 0.4 0.86 9.9 0.1 2.0 1 1 1 2 2 2 0 PIN domain PBP PF01161.15 AJZ76101.1 - 3.7e-35 120.9 0.0 4.1e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein EIF_2_alpha PF07541.7 AJZ76102.1 - 4.6e-23 81.0 0.2 9.6e-23 80.0 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 AJZ76102.1 - 2.7e-10 40.1 0.3 5.5e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 S1 RNA binding domain S1_2 PF13509.1 AJZ76102.1 - 0.033 14.0 0.1 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 S1 domain COG5 PF10392.4 AJZ76102.1 - 0.054 13.4 0.2 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 GATase_3 PF07685.9 AJZ76103.1 - 4.1e-33 114.1 0.2 6.3e-33 113.5 0.2 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.18 AJZ76103.1 - 7.1e-24 84.2 0.0 1.6e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 AJZ76103.1 - 1.7e-20 73.5 0.6 4.3e-18 65.6 0.4 2.4 1 1 0 1 1 1 1 AAA domain SNO PF01174.14 AJZ76103.1 - 0.0055 16.3 0.0 0.015 14.9 0.0 1.7 1 1 1 2 2 2 1 SNO glutamine amidotransferase family DUF4564 PF15169.1 AJZ76103.1 - 0.061 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) CTP_synth_N PF06418.9 AJZ76103.1 - 0.074 12.1 0.3 0.074 12.1 0.2 1.6 2 0 0 2 2 2 0 CTP synthase N-terminus Fer4_NifH PF00142.13 AJZ76103.1 - 0.083 12.0 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MobB PF03205.9 AJZ76103.1 - 0.22 11.2 3.1 0.89 9.2 0.1 2.9 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B CbiC PF02570.10 AJZ76104.1 - 5.2e-72 241.4 0.3 5.8e-72 241.2 0.2 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase CbiX PF01903.12 AJZ76105.1 - 1.5e-34 118.2 0.0 9.1e-17 61.0 0.0 2.1 2 0 0 2 2 2 2 CbiX Ferrochelatase PF00762.14 AJZ76105.1 - 8.2e-06 25.0 0.0 0.00015 20.8 0.0 2.0 1 1 0 1 1 1 1 Ferrochelatase DUF4263 PF14082.1 AJZ76105.1 - 0.096 12.6 0.2 0.82 9.6 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4263) CbiD PF01888.12 AJZ76106.1 - 7.8e-85 283.9 7.2 7.8e-85 283.9 5.0 1.5 2 0 0 2 2 2 1 CbiD DUF3042 PF11240.3 AJZ76106.1 - 0.055 13.2 0.4 0.055 13.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) NAD_binding_10 PF13460.1 AJZ76107.1 - 3.3e-18 66.3 0.0 4.2e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AJZ76107.1 - 4.9e-13 49.0 0.0 8.1e-12 45.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AJZ76107.1 - 5.2e-10 38.6 0.1 0.0066 15.3 0.0 3.1 1 1 2 3 3 3 3 Male sterility protein NmrA PF05368.8 AJZ76107.1 - 2.8e-09 36.5 0.2 4.1e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 AJZ76107.1 - 1.1e-08 34.0 0.7 2.8e-07 29.5 0.6 2.2 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AJZ76107.1 - 2.4e-08 33.2 0.0 1.7e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 AJZ76107.1 - 0.018 13.9 0.5 0.12 11.2 0.0 2.1 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein S-AdoMet_synt_C PF02773.11 AJZ76108.1 - 1.4e-70 235.4 0.1 2.8e-70 234.4 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 AJZ76108.1 - 2e-52 176.2 0.1 1.4e-51 173.4 0.0 2.3 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 AJZ76108.1 - 1.2e-45 153.7 3.1 6e-45 151.5 0.1 2.5 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.14 AJZ76108.1 - 0.057 11.9 0.1 0.24 9.8 0.0 2.0 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Imm2 PF14426.1 AJZ76108.1 - 0.086 12.8 0.0 6.1 6.9 0.0 3.0 3 0 0 3 3 3 0 Immunity protein Imm2 Rad51 PF08423.6 AJZ76109.1 - 5.1e-25 87.8 0.2 5.7e-25 87.6 0.1 1.2 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 AJZ76109.1 - 2.3e-09 36.7 6.6 1.2e-06 27.8 0.1 2.4 2 1 0 2 2 2 2 KaiC AAA_25 PF13481.1 AJZ76109.1 - 1.2e-08 34.6 0.0 6.1e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.10 AJZ76109.1 - 4.4e-06 25.7 3.0 0.0012 17.7 0.7 2.1 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain Arch_ATPase PF01637.13 AJZ76109.1 - 0.00013 21.7 2.5 0.00041 20.1 1.7 1.9 1 1 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 AJZ76109.1 - 0.00018 21.8 0.2 0.0003 21.0 0.2 1.6 1 1 0 1 1 1 1 ABC transporter RecA PF00154.16 AJZ76109.1 - 0.00064 18.8 0.3 0.0016 17.6 0.2 1.7 1 1 0 1 1 1 1 recA bacterial DNA recombination protein Zot PF05707.7 AJZ76109.1 - 0.0022 17.4 0.3 0.0029 17.1 0.2 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Miro PF08477.8 AJZ76109.1 - 0.0029 18.0 1.2 0.016 15.6 0.6 2.2 1 1 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 AJZ76109.1 - 0.0029 17.7 0.2 0.012 15.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.12 AJZ76109.1 - 0.0088 15.8 1.4 0.013 15.3 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 UPF0079 PF02367.12 AJZ76109.1 - 0.009 15.6 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 AJZ76109.1 - 0.014 15.0 5.7 0.38 10.2 3.9 2.6 1 1 0 1 1 1 0 AAA domain DUF1831 PF08866.5 AJZ76109.1 - 0.022 15.0 1.5 0.056 13.6 0.1 2.2 1 1 1 2 2 2 0 Putative amino acid metabolism AAA_10 PF12846.2 AJZ76109.1 - 0.03 13.7 0.1 0.046 13.1 0.1 1.3 1 1 0 1 1 1 0 AAA-like domain ATP-synt_ab PF00006.20 AJZ76109.1 - 0.051 13.0 0.0 0.055 12.9 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 AJZ76109.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PI-PLC-X PF00388.14 AJZ76109.1 - 0.12 11.7 2.4 0.21 10.9 1.2 1.7 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain Herpes_UL92 PF03048.9 AJZ76109.1 - 1.2 8.7 5.3 1.7 8.1 3.7 1.3 1 0 0 1 1 1 0 UL92 family DEAD_assoc PF08494.6 AJZ76110.1 - 6.7e-38 130.2 0.2 1.4e-37 129.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/H associated DEAD PF00270.24 AJZ76110.1 - 1.4e-35 122.2 0.3 5.8e-35 120.2 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AJZ76110.1 - 1e-17 63.7 0.0 3.7e-16 58.7 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AJZ76110.1 - 1e-09 38.5 0.1 5.7e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zn-ribbon_8 PF09723.5 AJZ76110.1 - 0.015 15.2 0.5 0.033 14.1 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF3039 PF11238.3 AJZ76110.1 - 0.13 11.7 0.8 0.35 10.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) SpoU_sub_bind PF08032.7 AJZ76110.1 - 0.18 11.9 2.7 4.6 7.4 0.1 3.4 4 0 0 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding zf-ribbon_3 PF13248.1 AJZ76110.1 - 0.31 10.3 0.5 0.63 9.3 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 AJZ76110.1 - 2.3 8.1 4.1 16 5.3 0.2 2.5 1 1 1 2 2 2 0 Transposase zinc-ribbon domain tRNA_anti-codon PF01336.20 AJZ76111.1 - 3.3e-12 46.0 0.1 0.0058 16.4 0.0 3.5 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain ABC_tran PF00005.22 AJZ76112.1 - 6.7e-29 100.9 0.0 1.1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJZ76112.1 - 6.4e-12 46.0 2.0 6.8e-10 39.3 0.3 2.5 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 AJZ76112.1 - 2.1e-06 27.0 1.1 2.7e-05 23.4 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain DUF4162 PF13732.1 AJZ76112.1 - 0.00014 22.3 1.7 0.00018 21.9 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_29 PF13555.1 AJZ76112.1 - 0.00032 20.1 0.2 0.00065 19.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 AJZ76112.1 - 0.0084 16.4 6.1 0.023 15.0 4.2 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AJZ76112.1 - 0.012 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.1 AJZ76112.1 - 0.022 14.6 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 AJZ76112.1 - 0.028 13.6 0.1 3.5 6.7 0.0 2.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF1954 PF09199.5 AJZ76112.1 - 0.028 14.5 0.1 0.086 13.0 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF1954) Securin PF04856.8 AJZ76112.1 - 0.031 13.9 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor FlgI PF02119.11 AJZ76112.1 - 0.032 12.8 0.2 0.049 12.2 0.1 1.2 1 0 0 1 1 1 0 Flagellar P-ring protein Sarcoglycan_1 PF04790.8 AJZ76112.1 - 0.086 11.9 0.9 0.6 9.2 0.1 2.0 2 0 0 2 2 2 0 Sarcoglycan complex subunit protein AAA_10 PF12846.2 AJZ76112.1 - 0.095 12.1 0.2 1.3 8.3 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 AJZ76112.1 - 0.11 12.4 2.4 1.8 8.5 0.4 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane PF01061.19 AJZ76113.1 - 5.8e-20 71.3 24.6 5.8e-20 71.3 17.1 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 AJZ76113.1 - 1.3e-14 53.9 39.9 6e-14 51.8 20.9 2.0 1 1 1 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 AJZ76113.1 - 7e-11 41.7 33.0 9.8e-11 41.2 22.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF354 PF04007.7 AJZ76114.1 - 2.3e-47 161.5 5.0 2.6e-47 161.3 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF354) Epimerase_2 PF02350.14 AJZ76114.1 - 3.4e-05 22.7 0.2 0.00026 19.8 0.2 1.9 2 0 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase LpxB PF02684.10 AJZ76114.1 - 0.0039 15.8 0.2 0.0083 14.7 0.1 1.6 1 1 0 1 1 1 1 Lipid-A-disaccharide synthetase Glycos_transf_1 PF00534.15 AJZ76114.1 - 0.024 14.0 0.2 0.084 12.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_trans_1_3 PF13528.1 AJZ76114.1 - 0.085 12.0 0.1 0.35 10.0 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 1 3HCDH_N PF02737.13 AJZ76115.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GrpE PF01025.14 AJZ76116.1 - 8e-36 123.0 0.1 8.8e-36 122.9 0.1 1.0 1 0 0 1 1 1 1 GrpE HSP70 PF00012.15 AJZ76117.1 - 4.5e-216 718.4 13.1 1.9e-196 653.6 6.5 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 AJZ76117.1 - 2.2e-16 59.3 4.5 2.2e-16 59.3 3.1 2.4 2 1 0 2 2 2 1 MreB/Mbl protein StbA PF06406.6 AJZ76117.1 - 0.00037 19.5 0.7 0.56 9.0 0.0 2.3 1 1 1 2 2 2 2 StbA protein FGGY_C PF02782.11 AJZ76117.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 AJZ76117.1 - 4.7 7.0 10.9 13 5.6 0.1 4.4 3 1 1 4 4 4 0 Cell division protein FtsA CTDII PF01556.13 AJZ76118.1 - 5.8e-26 90.2 4.3 1.9e-22 78.9 0.5 3.1 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 AJZ76118.1 - 7.2e-25 86.5 2.6 1.1e-24 85.9 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AJZ76118.1 - 1.6e-15 56.8 17.3 2.8e-15 56.1 12.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 AJZ76118.1 - 2 8.8 7.2 4.5 7.6 5.0 1.7 1 1 0 1 1 1 0 Cytochrome c3 DUF1275 PF06912.6 AJZ76119.1 - 0.032 13.4 1.9 0.049 12.8 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) DUF202 PF02656.10 AJZ76119.1 - 0.083 13.1 3.4 2 8.6 2.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) UbiA PF01040.13 AJZ76119.1 - 0.1 11.7 6.6 0.15 11.2 4.6 1.4 1 1 0 1 1 1 0 UbiA prenyltransferase family Dpy19 PF10034.4 AJZ76119.1 - 1.5 6.9 8.4 1.6 6.8 5.8 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation GatB_N PF02934.10 AJZ76121.1 - 1.9e-72 243.5 0.0 2.7e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 AJZ76121.1 - 4.5e-18 65.3 0.4 1e-17 64.2 0.3 1.6 1 0 0 1 1 1 1 GatB domain GAD PF02938.9 AJZ76121.1 - 3.3e-09 36.7 0.0 1e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 GAD domain Asparaginase PF00710.15 AJZ76122.1 - 9.8e-83 277.5 0.0 1.2e-82 277.3 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Sec61_beta PF03911.11 AJZ76122.1 - 0.019 14.7 0.3 0.045 13.5 0.2 1.6 1 0 0 1 1 1 0 Sec61beta family AAA PF00004.24 AJZ76123.1 - 6.7e-100 330.4 0.0 4.3e-50 169.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AJZ76123.1 - 7.1e-30 102.8 0.6 3e-29 100.8 0.2 2.4 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 AJZ76123.1 - 6.7e-16 58.6 0.0 3.2e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 AJZ76123.1 - 7.8e-16 57.8 0.0 6.6e-09 35.1 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AJZ76123.1 - 8.2e-15 55.2 0.1 3.7e-06 27.0 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 AJZ76123.1 - 6.4e-13 48.9 0.1 3.9e-05 23.7 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AJZ76123.1 - 6.6e-12 46.3 0.1 2e-05 25.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AJZ76123.1 - 1e-10 41.4 0.9 0.00019 21.1 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AJZ76123.1 - 1.1e-10 41.5 0.0 0.00018 21.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.8 AJZ76123.1 - 1.1e-10 40.8 0.0 0.00011 21.0 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 AJZ76123.1 - 6.7e-10 38.9 0.0 0.00071 19.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AJZ76123.1 - 2.4e-09 36.5 0.0 4.3e-05 22.7 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 AJZ76123.1 - 8e-09 35.1 0.2 0.0036 16.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 AJZ76123.1 - 5.5e-08 32.8 0.0 0.0014 18.3 0.0 3.8 2 1 1 3 3 3 1 Archaeal ATPase CDC48_2 PF02933.12 AJZ76123.1 - 1.3e-07 31.1 0.1 3.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Sigma54_activat PF00158.21 AJZ76123.1 - 1.8e-07 30.7 0.1 0.039 13.4 0.0 3.5 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_18 PF13238.1 AJZ76123.1 - 5.2e-07 30.0 0.3 0.023 15.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 AJZ76123.1 - 9.1e-07 29.0 0.0 0.037 14.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 AJZ76123.1 - 1.5e-06 27.8 2.6 0.0051 16.5 0.1 3.5 3 0 0 3 3 3 2 Part of AAA domain Bac_DnaA PF00308.13 AJZ76123.1 - 1.5e-06 28.0 0.1 0.0074 15.9 0.0 2.7 3 0 0 3 3 2 2 Bacterial dnaA protein NACHT PF05729.7 AJZ76123.1 - 2.2e-06 27.4 0.1 0.28 10.8 0.1 3.9 3 1 1 4 4 4 2 NACHT domain AAA_28 PF13521.1 AJZ76123.1 - 4.3e-06 26.7 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AJZ76123.1 - 1.1e-05 24.9 9.8 0.59 9.4 0.3 5.1 3 2 1 4 4 4 2 AAA domain Mg_chelatase PF01078.16 AJZ76123.1 - 1.5e-05 24.2 0.7 0.033 13.3 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NB-ARC PF00931.17 AJZ76123.1 - 1.6e-05 23.9 0.0 0.087 11.6 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.1 AJZ76123.1 - 2.8e-05 23.7 0.3 0.026 14.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.1 AJZ76123.1 - 3.5e-05 23.8 0.0 0.084 12.9 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain KaiC PF06745.8 AJZ76123.1 - 3.7e-05 22.9 1.3 0.29 10.1 0.0 4.2 3 1 1 4 4 4 1 KaiC ABC_tran PF00005.22 AJZ76123.1 - 8.5e-05 22.8 0.0 0.68 10.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter NTPase_1 PF03266.10 AJZ76123.1 - 0.0001 22.0 0.3 1.7 8.3 0.0 3.9 2 1 1 3 3 3 1 NTPase PhoH PF02562.11 AJZ76123.1 - 0.00013 21.2 0.2 0.22 10.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.8 AJZ76123.1 - 0.00017 20.5 0.0 0.059 12.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 AJZ76123.1 - 0.00018 21.0 0.0 0.32 10.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 AJZ76123.1 - 0.0009 19.1 0.1 0.76 9.6 0.0 2.9 3 0 0 3 3 3 1 Shikimate kinase ATP-synt_ab PF00006.20 AJZ76123.1 - 0.0021 17.6 0.0 0.94 8.9 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 AJZ76123.1 - 0.0024 17.4 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AFG1_ATPase PF03969.11 AJZ76123.1 - 0.0033 16.2 0.0 0.9 8.2 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase Guanylate_kin PF00625.16 AJZ76123.1 - 0.0074 15.7 0.8 4.1 6.7 0.0 3.7 3 1 1 4 4 4 0 Guanylate kinase DUF2075 PF09848.4 AJZ76123.1 - 0.0082 15.1 0.0 0.32 9.9 0.0 2.6 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 AJZ76123.1 - 0.01 14.7 0.0 1.4 7.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 AJZ76123.1 - 0.011 14.9 0.0 0.55 9.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ResIII PF04851.10 AJZ76123.1 - 0.011 15.5 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 AJZ76123.1 - 0.012 14.5 0.0 0.25 10.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.1 AJZ76123.1 - 0.015 14.8 0.1 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.1 AJZ76123.1 - 0.017 14.7 0.0 4.1 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AJZ76123.1 - 0.021 14.3 0.4 3.3 7.0 0.0 3.2 2 2 0 3 3 3 0 AAA-like domain CPT PF07931.7 AJZ76123.1 - 0.034 13.7 0.1 5.3 6.6 0.0 2.9 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.13 AJZ76123.1 - 0.06 12.8 0.0 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 AJZ76123.1 - 0.068 12.1 0.2 6.9 5.5 0.0 3.0 2 2 0 3 3 3 0 KAP family P-loop domain PduV-EutP PF10662.4 AJZ76123.1 - 0.072 12.5 0.0 22 4.5 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_L2_C PF03947.13 AJZ76124.1 - 8.8e-32 109.6 2.0 5.1e-31 107.1 1.8 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AJZ76124.1 - 4.3e-07 29.8 0.0 1.1e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain NIL PF09383.5 AJZ76124.1 - 0.037 13.6 0.2 0.074 12.6 0.1 1.5 1 0 0 1 1 1 0 NIL domain Acylphosphatase PF00708.13 AJZ76125.1 - 2.9e-26 91.3 0.8 3.2e-26 91.2 0.6 1.0 1 0 0 1 1 1 1 Acylphosphatase Invasin_D3 PF09134.5 AJZ76126.1 - 0.047 13.5 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Invasin, domain 3 ATP_bind_3 PF01171.15 AJZ76127.1 - 5.7e-20 71.5 0.0 8.2e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 AJZ76127.1 - 0.004 16.0 0.1 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 AJZ76127.1 - 0.0045 15.5 0.0 0.0072 14.9 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase C1_1 PF00130.17 AJZ76127.1 - 0.025 14.3 2.9 0.025 14.3 2.0 3.7 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2392 PF10288.4 AJZ76127.1 - 0.027 14.7 0.0 0.081 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2392) PAPS_reduct PF01507.14 AJZ76127.1 - 0.033 14.0 0.0 0.066 13.0 0.0 1.8 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.16 AJZ76127.1 - 0.13 11.6 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Peptidase_M50 PF02163.17 AJZ76128.1 - 2.8e-24 85.1 0.1 1.3e-23 82.9 0.1 1.9 1 1 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.1 AJZ76128.1 - 6.7e-11 41.9 0.1 1.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 AJZ76128.1 - 5.6e-05 23.2 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 AJZ76128.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain eRF1_1 PF03463.10 AJZ76129.1 - 9.3e-17 60.8 1.8 1.7e-16 59.9 1.2 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 AJZ76129.1 - 1.8e-12 47.7 0.1 3.7e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AJZ76129.1 - 2.9e-10 40.4 3.4 5.3e-10 39.5 0.4 2.6 3 0 0 3 3 3 1 eRF1 domain 3 UPF0047 PF01894.12 AJZ76131.1 - 3.1e-38 130.2 0.0 3.6e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fe_dep_repr_C PF02742.10 AJZ76132.1 - 4.1e-20 71.2 0.8 5e-20 70.9 0.0 1.6 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.14 AJZ76132.1 - 2e-16 59.6 0.2 3.3e-16 58.9 0.2 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_27 PF13463.1 AJZ76132.1 - 3e-05 24.2 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.17 AJZ76132.1 - 3.7e-05 23.3 0.0 5.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.15 AJZ76132.1 - 8.4e-05 22.6 0.1 0.00015 21.7 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.2 AJZ76132.1 - 0.00014 21.4 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.1 AJZ76132.1 - 0.00028 20.6 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_5 PF01022.15 AJZ76132.1 - 0.00044 19.8 0.1 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family TrmB PF01978.14 AJZ76132.1 - 0.0008 19.0 0.2 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIE_beta PF02186.10 AJZ76132.1 - 0.00099 19.0 0.2 0.0022 17.9 0.2 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain HTH_1 PF00126.22 AJZ76132.1 - 0.004 16.8 0.0 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_45 PF14947.1 AJZ76132.1 - 0.0051 16.5 0.1 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_12 PF08461.5 AJZ76132.1 - 0.024 14.3 0.0 0.052 13.2 0.0 1.5 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_11 PF08279.7 AJZ76132.1 - 0.026 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 HTH domain IF2_N PF04760.10 AJZ76132.1 - 0.03 13.9 0.4 0.09 12.4 0.1 2.0 2 1 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region NLPC_P60 PF00877.14 AJZ76132.1 - 0.042 13.6 0.0 0.088 12.6 0.0 1.5 1 1 0 1 1 1 0 NlpC/P60 family HTH_6 PF01418.12 AJZ76132.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Rio2_N PF09202.6 AJZ76132.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Rio2, N-terminal TrmB PF01978.14 AJZ76133.1 - 1.3e-22 79.3 0.7 2.2e-21 75.3 0.0 3.0 3 1 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 AJZ76133.1 - 1.3e-07 30.8 0.0 1.6e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_IclR PF09339.5 AJZ76133.1 - 0.00038 19.9 0.0 0.0011 18.5 0.0 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.1 AJZ76133.1 - 0.00044 19.5 0.0 0.0014 17.9 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 AJZ76133.1 - 0.0038 17.5 0.0 0.025 14.8 0.0 2.2 2 0 0 2 2 2 1 Winged helix DNA-binding domain Penicillinase_R PF03965.11 AJZ76133.1 - 0.017 15.1 0.2 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 Penicillinase repressor Rrf2 PF02082.15 AJZ76133.1 - 0.034 14.2 0.0 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator MarR PF01047.17 AJZ76133.1 - 0.038 13.6 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 MarR family GntR PF00392.16 AJZ76133.1 - 0.078 12.4 0.1 1.2 8.6 0.0 2.6 3 1 0 3 3 3 0 Bacterial regulatory proteins, gntR family PadR PF03551.9 AJZ76133.1 - 0.088 12.5 0.0 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family HTH_5 PF01022.15 AJZ76133.1 - 0.097 12.3 0.0 0.84 9.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_9 PF08221.6 AJZ76133.1 - 0.13 12.1 1.2 0.26 11.1 0.0 2.1 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Glycos_transf_1 PF00534.15 AJZ76134.1 - 3.7e-23 81.8 0.3 3.4e-22 78.6 0.2 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AJZ76134.1 - 3.3e-08 33.7 0.0 5.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AJZ76134.1 - 5.1e-08 33.0 0.0 8.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 AJZ76134.1 - 2.2e-06 27.5 0.1 2e-05 24.4 0.1 2.3 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_4_4 PF13579.1 AJZ76134.1 - 0.00061 19.9 0.0 0.0014 18.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Epimerase_2 PF02350.14 AJZ76134.1 - 0.0044 15.8 0.5 0.012 14.4 0.0 1.8 2 0 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase PIGA PF08288.7 AJZ76134.1 - 0.13 12.6 0.1 1.5 9.2 0.0 2.2 1 1 1 2 2 2 0 PIGA (GPI anchor biosynthesis) Epimerase PF01370.16 AJZ76135.1 - 6.2e-58 196.0 0.0 7.2e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AJZ76135.1 - 4.7e-26 91.1 0.0 6.4e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AJZ76135.1 - 1.5e-22 79.7 0.0 1.9e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 AJZ76135.1 - 2e-19 69.6 0.0 1.2e-18 67.1 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 AJZ76135.1 - 4.3e-17 61.8 0.0 5.6e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 AJZ76135.1 - 6.6e-08 32.7 0.0 9.2e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AJZ76135.1 - 2.8e-06 27.3 0.0 4.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase_Csub PF13950.1 AJZ76135.1 - 0.00049 19.9 0.0 0.00092 19.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit KR PF08659.5 AJZ76135.1 - 0.0011 18.6 0.0 0.0098 15.5 0.0 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 AJZ76135.1 - 0.0051 16.0 0.1 0.047 12.9 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Ldh_1_N PF00056.18 AJZ76135.1 - 0.03 14.1 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.15 AJZ76135.1 - 0.083 12.8 0.1 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF3460 PF11943.3 AJZ76135.1 - 0.11 12.6 0.1 0.52 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) Asn_synthase PF00733.16 AJZ76136.1 - 1.6e-28 99.8 0.0 2.2e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 AJZ76136.1 - 0.00023 20.1 1.1 0.00068 18.6 0.0 2.1 3 0 0 3 3 3 1 NAD synthase ATP_bind_3 PF01171.15 AJZ76136.1 - 0.00024 20.6 0.1 0.0024 17.3 0.0 2.4 2 0 0 2 2 2 1 PP-loop family tRNA_Me_trans PF03054.11 AJZ76136.1 - 0.022 13.3 0.0 0.039 12.5 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase QueC PF06508.8 AJZ76136.1 - 0.06 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Glycos_transf_1 PF00534.15 AJZ76137.1 - 4.8e-24 84.7 0.0 7.9e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AJZ76137.1 - 5.9e-14 52.3 0.0 9.3e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AJZ76137.1 - 1.4e-10 41.3 0.0 2.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AJZ76137.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.5 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Methyltransf_11 PF08241.7 AJZ76138.1 - 4.3e-16 59.1 0.0 7.6e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJZ76138.1 - 8.8e-16 57.8 0.2 1.5e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJZ76138.1 - 1.3e-13 51.0 0.2 1.4e-12 47.6 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJZ76138.1 - 5.7e-10 39.4 0.0 5.6e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJZ76138.1 - 6.8e-08 32.8 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJZ76138.1 - 7.1e-08 33.0 0.0 1.3e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AJZ76138.1 - 3.6e-07 29.5 0.2 3.3e-06 26.3 0.1 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AJZ76138.1 - 7.7e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 AJZ76138.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Glycos_transf_1 PF00534.15 AJZ76139.1 - 9.8e-26 90.1 0.0 3.7e-25 88.3 0.0 1.9 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AJZ76139.1 - 2.8e-14 53.4 0.0 4.7e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AJZ76139.1 - 2e-10 40.7 0.0 4.6e-10 39.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AJZ76139.1 - 0.00022 21.0 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.1 AJZ76139.1 - 0.00048 19.9 0.7 0.001 18.9 0.5 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Methyltransf_24 PF13578.1 AJZ76140.1 - 6.8e-08 33.2 0.0 1.2e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TylF PF05711.6 AJZ76140.1 - 2.4e-05 23.5 0.0 3.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Epimerase PF01370.16 AJZ76141.1 - 8.1e-50 169.4 0.0 9.9e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AJZ76141.1 - 3.2e-18 65.4 0.0 4.5e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AJZ76141.1 - 2.3e-17 62.7 0.0 3.3e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 AJZ76141.1 - 9e-17 60.9 0.1 6.6e-16 58.0 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 AJZ76141.1 - 1.9e-14 53.2 0.0 1.6e-11 43.6 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 AJZ76141.1 - 7.4e-14 52.1 0.0 9.1e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AJZ76141.1 - 5e-08 33.0 0.0 6e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 AJZ76141.1 - 2.1e-05 23.8 0.0 4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Ldh_1_N PF00056.18 AJZ76141.1 - 0.0056 16.5 0.0 0.013 15.3 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 AJZ76141.1 - 0.011 15.4 0.0 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 AJZ76141.1 - 0.019 14.6 0.2 0.098 12.3 0.2 2.2 1 1 0 1 1 1 0 KR domain Saccharop_dh PF03435.13 AJZ76141.1 - 0.031 13.2 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 AJZ76141.1 - 0.11 11.6 0.1 0.25 10.4 0.0 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glycos_transf_1 PF00534.15 AJZ76142.1 - 7e-32 110.1 0.0 1.1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AJZ76142.1 - 1.4e-17 64.1 0.0 2.2e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AJZ76142.1 - 4.4e-15 55.8 0.0 6e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 AJZ76142.1 - 1.7e-05 24.9 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 EAL PF00563.15 AJZ76142.1 - 0.075 12.5 0.0 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 EAL domain Glyco_trans_4_4 PF13579.1 AJZ76142.1 - 0.091 12.9 0.0 0.75 9.9 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain DUF4431 PF14485.1 AJZ76142.1 - 0.092 12.3 0.1 0.29 10.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) Epimerase PF01370.16 AJZ76143.1 - 6.6e-49 166.4 0.0 8.6e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AJZ76143.1 - 4.2e-19 68.5 0.0 4.7e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 AJZ76143.1 - 2.6e-12 46.0 0.0 3.4e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AJZ76143.1 - 4.2e-11 42.2 0.0 9.3e-09 34.5 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 AJZ76143.1 - 1.9e-08 33.5 0.1 3.8e-08 32.5 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 AJZ76143.1 - 3.5e-07 29.5 0.0 4.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 AJZ76143.1 - 8.7e-07 29.1 0.0 1.1e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AJZ76143.1 - 2.3e-05 24.3 0.0 3.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 AJZ76143.1 - 7.9e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 AJZ76143.1 - 0.00065 19.4 0.0 0.00083 19.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 AJZ76143.1 - 0.0013 17.9 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Glyco_transf_4 PF13439.1 AJZ76143.1 - 0.0042 16.8 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Semialdhyde_dh PF01118.19 AJZ76143.1 - 0.09 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_transf_5 PF08323.6 AJZ76143.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain NAD_binding_3 PF03447.11 AJZ76143.1 - 0.1 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain MGDG_synth PF06925.6 AJZ76143.1 - 0.11 12.3 1.3 0.16 11.8 0.2 1.8 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase DUF3473 PF11959.3 AJZ76144.1 - 1.5e-29 102.1 0.1 2.2e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3473) Polysacc_deac_1 PF01522.16 AJZ76144.1 - 4.7e-14 52.0 0.0 9e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Hexapep PF00132.19 AJZ76145.1 - 8.3e-13 47.2 10.2 3.5e-07 29.4 1.1 3.7 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AJZ76145.1 - 2.1e-07 30.3 10.4 0.0094 15.4 1.8 4.0 2 2 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NIF PF03031.13 AJZ76146.1 - 2.5e-06 27.2 0.3 7.9e-06 25.6 0.2 1.9 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Acid_PPase PF12689.2 AJZ76146.1 - 2e-05 24.2 2.5 0.00064 19.3 1.7 2.6 1 1 0 1 1 1 1 Acid Phosphatase Acetyltransf_10 PF13673.1 AJZ76146.1 - 2.7e-05 24.2 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PP-binding PF00550.20 AJZ76147.1 - 0.0039 17.4 0.0 0.0052 17.0 0.0 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF3013 PF11217.3 AJZ76147.1 - 0.034 13.8 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3013) MaoC_dehydratas PF01575.14 AJZ76148.1 - 1.4e-23 82.5 0.0 1.6e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 AJZ76148.1 - 1.8e-08 34.2 0.0 8.3e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 AJZ76148.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase superfamily Histidinol_dh PF00815.15 AJZ76148.1 - 0.092 11.3 0.0 0.098 11.2 0.0 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase ACPS PF01648.15 AJZ76149.1 - 1.4e-14 53.8 0.1 1.6e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily NTP_transferase PF00483.18 AJZ76150.1 - 4.7e-57 193.1 0.0 5.9e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 AJZ76150.1 - 6.8e-12 44.3 11.0 3.3e-07 29.5 0.9 3.9 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 AJZ76150.1 - 2.4e-11 43.9 0.0 3.3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 AJZ76150.1 - 7.2e-07 28.6 7.0 7.4e-06 25.4 2.4 3.2 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Epimerase PF01370.16 AJZ76151.1 - 4.8e-61 206.2 0.0 6.2e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AJZ76151.1 - 9e-20 70.5 0.0 1.3e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AJZ76151.1 - 1.5e-19 70.0 0.0 1.8e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 AJZ76151.1 - 1.2e-13 50.5 0.0 3.6e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 AJZ76151.1 - 8.3e-13 47.8 0.6 1e-11 44.2 0.4 2.1 1 1 0 1 1 1 1 Male sterility protein Glyco_trans_1_3 PF13528.1 AJZ76151.1 - 5e-06 25.9 0.0 1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 1 NAD_binding_10 PF13460.1 AJZ76151.1 - 9.3e-05 22.5 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AJZ76151.1 - 0.0041 17.0 0.0 0.0088 15.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 AJZ76151.1 - 0.047 13.6 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus FdtA PF05523.6 AJZ76152.1 - 5.7e-18 64.6 0.1 6.5e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 WxcM-like, C-terminal Cupin_2 PF07883.6 AJZ76152.1 - 0.00014 21.2 0.0 0.00043 19.7 0.0 1.9 1 1 0 1 1 1 1 Cupin domain Glycos_transf_2 PF00535.21 AJZ76153.1 - 1.5e-23 83.2 0.3 2.1e-23 82.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AJZ76153.1 - 0.0035 17.1 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 AJZ76153.1 - 0.062 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 RseC_MucC PF04246.7 AJZ76153.1 - 0.078 12.5 0.2 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC RmlD_sub_bind PF04321.12 AJZ76154.1 - 2.7e-54 184.0 0.0 3.3e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 AJZ76154.1 - 8.9e-22 77.6 0.0 1.3e-21 77.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AJZ76154.1 - 5.1e-09 35.4 0.4 1.8e-07 30.3 0.0 2.4 3 0 0 3 3 3 1 Male sterility protein Polysacc_synt_2 PF02719.10 AJZ76154.1 - 1.6e-08 33.8 3.1 5.6e-06 25.4 0.3 2.5 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 AJZ76154.1 - 4.3e-08 32.1 1.2 8.9e-08 31.1 0.9 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 AJZ76154.1 - 3e-05 24.1 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 AJZ76154.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 AJZ76154.1 - 0.072 12.3 0.2 0.62 9.2 0.0 2.4 3 0 0 3 3 3 0 NmrA-like family dTDP_sugar_isom PF00908.12 AJZ76155.1 - 1.5e-60 203.5 0.0 1.6e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase FdtA PF05523.6 AJZ76155.1 - 0.00054 19.4 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 WxcM-like, C-terminal ARD PF03079.9 AJZ76155.1 - 0.011 15.7 0.4 0.013 15.4 0.3 1.2 1 0 0 1 1 1 0 ARD/ARD' family Methyltransf_14 PF08484.6 AJZ76156.1 - 2.1e-59 199.6 0.0 3.3e-59 199.0 0.0 1.3 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Methyltransf_23 PF13489.1 AJZ76156.1 - 2.8e-18 66.1 0.1 6.8e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_13 PF08421.6 AJZ76156.1 - 7.9e-17 60.5 0.3 1.3e-16 59.8 0.2 1.4 1 0 0 1 1 1 1 Putative zinc binding domain Methyltransf_11 PF08241.7 AJZ76156.1 - 1.7e-11 44.4 0.1 1.3e-10 41.5 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJZ76156.1 - 1.4e-08 34.4 0.0 4.2e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJZ76156.1 - 8.8e-08 32.5 0.0 2.5e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJZ76156.1 - 7.4e-05 23.2 0.0 0.00018 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 AJZ76156.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NTP_transferase PF00483.18 AJZ76157.1 - 1e-16 60.9 0.0 3.5e-16 59.2 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AJZ76157.1 - 2.5e-07 30.9 0.0 3.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 AJZ76157.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glyco_trans_1_2 PF13524.1 AJZ76158.1 - 2e-08 34.4 0.0 7.2e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Capsule_synth PF05159.9 AJZ76159.1 - 2.3e-07 30.5 0.2 3.9e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein DUF354 PF04007.7 AJZ76159.1 - 0.00027 19.9 0.0 0.00056 18.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF354) Epimerase_2 PF02350.14 AJZ76159.1 - 0.0022 16.8 0.0 0.0045 15.8 0.0 1.5 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Polysacc_synt PF01943.12 AJZ76160.1 - 5e-07 29.2 34.5 5e-07 29.2 23.9 3.0 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.1 AJZ76160.1 - 0.011 15.5 9.5 0.011 15.5 6.6 4.3 3 1 2 5 5 5 0 Polysaccharide biosynthesis C-terminal domain Epimerase_2 PF02350.14 AJZ76162.1 - 1.1e-84 284.1 0.9 1.3e-84 283.9 0.6 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Peroxin-22 PF12827.2 AJZ76162.1 - 0.012 15.2 0.6 1.7 8.3 0.0 2.8 2 1 1 3 3 3 0 Peroxisomal biogenesis protein family Spore_YtrH PF14034.1 AJZ76162.1 - 0.067 13.1 0.2 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 Sporulation protein YtrH DRTGG PF07085.7 AJZ76162.1 - 0.11 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 DRTGG domain NeuB PF03102.9 AJZ76163.1 - 9.1e-71 237.8 0.0 1.1e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.7 AJZ76163.1 - 4.5e-10 39.7 0.0 1.3e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 SAF domain CTP_transf_3 PF02348.14 AJZ76164.1 - 5e-25 88.4 0.0 6.1e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.2 AJZ76164.1 - 4.5e-05 23.5 0.0 5.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 AJZ76164.1 - 0.1 12.0 0.1 0.14 11.6 0.0 1.3 1 1 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GFO_IDH_MocA PF01408.17 AJZ76165.1 - 1.3e-19 70.8 0.0 2.4e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AJZ76165.1 - 0.00025 20.7 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.14 AJZ76165.1 - 0.0013 17.9 0.0 0.017 14.3 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 AJZ76165.1 - 0.0021 17.9 0.1 0.069 12.9 0.0 2.4 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.19 AJZ76165.1 - 0.0023 17.8 0.2 0.01 15.7 0.0 2.2 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ApbA PF02558.11 AJZ76165.1 - 0.0031 16.9 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 AJZ76165.1 - 0.0037 16.6 0.0 0.0077 15.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 AJZ76165.1 - 0.0091 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 AJZ76165.1 - 0.014 14.4 0.0 0.027 13.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 AJZ76165.1 - 0.014 15.6 1.2 0.054 13.7 0.1 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding DUF3699 PF12480.3 AJZ76165.1 - 0.13 11.8 0.6 4.2 7.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3699) Glyphos_transf PF04464.9 AJZ76166.1 - 2.4e-06 26.5 0.1 7.7e-06 24.9 0.0 1.7 1 1 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Capsule_synth PF05159.9 AJZ76166.1 - 2.2e-05 24.0 0.7 0.00039 20.0 0.1 2.9 2 1 0 2 2 2 1 Capsule polysaccharide biosynthesis protein Abhydro_lipase PF04083.11 AJZ76166.1 - 0.01 15.1 0.0 0.035 13.4 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Polyketide_cyc PF03364.15 AJZ76167.1 - 0.0083 16.1 0.0 0.013 15.5 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Bet_v_1 PF00407.14 AJZ76167.1 - 0.049 13.2 0.3 0.078 12.5 0.1 1.3 1 1 0 1 1 1 0 Pathogenesis-related protein Bet v I family 2OG-FeII_Oxy_3 PF13640.1 AJZ76168.1 - 4.5e-06 27.0 0.1 9.2e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 AJZ76168.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Polysacc_synt_2 PF02719.10 AJZ76169.1 - 3.6e-97 324.8 1.4 5e-97 324.3 1.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 AJZ76169.1 - 4.4e-26 91.7 0.7 5.9e-25 88.0 0.5 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AJZ76169.1 - 1.4e-23 83.0 1.2 7.4e-21 74.0 0.1 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AJZ76169.1 - 6e-15 54.8 0.0 4.1e-13 48.8 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 AJZ76169.1 - 9.8e-13 48.5 0.0 1.4e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 AJZ76169.1 - 5e-11 41.9 1.9 9.8e-09 34.4 0.5 2.7 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.20 AJZ76169.1 - 1.2e-08 35.0 0.0 1.9e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 AJZ76169.1 - 1.4e-06 27.7 0.0 2.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 AJZ76169.1 - 3.5e-05 23.5 0.0 5.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 AJZ76169.1 - 0.00024 21.4 0.0 0.00087 19.6 0.0 2.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 AJZ76169.1 - 0.00034 20.7 0.1 0.00034 20.7 0.1 2.4 3 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 AJZ76169.1 - 0.0024 18.1 0.0 0.014 15.6 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 AJZ76169.1 - 0.0056 15.7 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 AJZ76169.1 - 0.015 15.0 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 AJZ76169.1 - 0.017 15.1 0.1 0.047 13.6 0.1 1.9 1 1 0 1 1 1 0 TrkA-N domain CTP_transf_3 PF02348.14 AJZ76170.1 - 2e-30 106.0 0.3 2.3e-30 105.8 0.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.2 AJZ76170.1 - 0.0076 16.3 0.0 0.043 13.8 0.0 2.0 1 1 0 1 1 1 1 MobA-like NTP transferase domain NeuB PF03102.9 AJZ76171.1 - 8.4e-76 254.2 0.0 1e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.7 AJZ76171.1 - 0.0087 16.4 0.1 0.026 14.8 0.0 1.8 2 0 0 2 2 2 1 SAF domain AP_endonuc_2 PF01261.19 AJZ76171.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Formyl_trans_N PF00551.14 AJZ76172.1 - 7.2e-16 58.2 0.0 1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 AJZ76172.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain DUF1242 PF06842.7 AJZ76172.1 - 0.12 11.8 0.1 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) Acetyltransf_4 PF13420.1 AJZ76173.1 - 5.4e-18 65.4 3.1 6.4e-18 65.1 2.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AJZ76173.1 - 2.5e-12 47.1 0.8 3.3e-12 46.7 0.6 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AJZ76173.1 - 0.00041 20.2 0.5 0.0031 17.3 0.4 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AJZ76173.1 - 0.044 13.8 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TrkA_N PF02254.13 AJZ76174.1 - 0.0049 16.8 0.0 0.03 14.3 0.0 2.2 3 0 0 3 3 3 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 AJZ76174.1 - 0.059 12.7 0.4 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain bact-PGI_C PF10432.4 AJZ76175.1 - 5.2e-40 136.6 0.0 9.8e-40 135.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal region SIS PF01380.17 AJZ76175.1 - 9.5e-07 28.4 0.7 1.6e-06 27.7 0.2 1.6 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 AJZ76175.1 - 0.36 10.5 4.2 0.22 11.2 0.3 2.5 3 0 0 3 3 3 0 SIS domain IF-2B PF01008.12 AJZ76176.1 - 2.7e-86 289.0 1.0 3.2e-86 288.8 0.7 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF59 PF01883.14 AJZ76177.1 - 4.5e-16 58.5 0.1 1.6e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF59 PqqD PF05402.7 AJZ76177.1 - 3.5e-08 33.3 0.0 5.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) DUF3139 PF11337.3 AJZ76178.1 - 0.012 15.8 0.1 0.016 15.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) tRNA-synt_2c PF01411.14 AJZ76178.1 - 0.072 11.3 0.0 0.084 11.1 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (A) Aminotran_1_2 PF00155.16 AJZ76179.1 - 7e-59 199.6 0.0 7.9e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 AJZ76179.1 - 1.2e-09 37.6 0.0 1.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 AJZ76179.1 - 1.3e-07 30.6 0.0 3.1e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AJZ76179.1 - 9.3e-05 21.7 0.0 0.00015 21.0 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AJZ76179.1 - 0.00012 20.4 0.0 0.00017 19.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.2 AJZ76179.1 - 0.0017 17.0 0.0 0.0048 15.5 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase OKR_DC_1 PF01276.15 AJZ76179.1 - 0.18 10.2 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pyridox_oxidase PF01243.15 AJZ76180.1 - 2.5e-17 62.6 0.0 3.5e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AJZ76180.1 - 7.6e-08 32.2 0.0 2.1e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2373 PF10180.4 AJZ76180.1 - 0.0012 18.2 0.1 0.0036 16.8 0.1 1.8 1 1 1 2 2 2 1 Uncharacterised conserved protein (DUF2373) DUF308 PF03729.8 AJZ76181.1 - 0.00068 19.5 0.3 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 Short repeat of unknown function (DUF308) YfzA PF14118.1 AJZ76181.1 - 0.0033 17.4 0.1 0.0036 17.3 0.1 1.1 1 0 0 1 1 1 1 YfzA-like protein L6_membrane PF05805.7 AJZ76181.1 - 0.075 12.5 1.1 0.092 12.2 0.7 1.0 1 0 0 1 1 1 0 L6 membrane protein F420_oxidored PF03807.12 AJZ76182.1 - 8.6e-16 58.1 0.0 1.6e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 AJZ76182.1 - 0.011 15.4 0.1 0.019 14.7 0.1 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 AJZ76182.1 - 0.024 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.15 AJZ76182.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus His_Phos_1 PF00300.17 AJZ76183.1 - 3.4e-33 114.9 0.0 4e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M42 PF05343.9 AJZ76183.1 - 0.02 13.6 0.2 0.27 9.9 0.1 2.0 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase UPF0104 PF03706.8 AJZ76184.1 - 0.038 13.2 0.2 0.039 13.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF4059 PF13268.1 AJZ76184.1 - 0.09 12.9 1.9 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) DUF2593 PF10767.4 AJZ76184.1 - 0.17 11.5 1.8 0.2 11.3 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) COX2 PF00116.15 AJZ76185.1 - 2.7e-21 75.5 0.4 1.6e-18 66.6 0.0 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.1 AJZ76185.1 - 4.5e-06 26.5 0.0 5.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain COX1 PF00115.15 AJZ76186.1 - 1.6e-137 458.8 59.3 2.3e-137 458.2 41.1 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Copper-bind PF00127.15 AJZ76187.1 - 2.9e-16 59.5 0.7 3.6e-08 33.5 0.1 2.5 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu-oxidase_3 PF07732.10 AJZ76187.1 - 8.3e-13 48.1 0.2 2.5e-05 23.9 0.0 2.7 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 AJZ76187.1 - 2.8e-08 33.5 0.0 0.00043 20.1 0.0 2.6 2 1 0 2 2 2 2 Cupredoxin-like domain SoxE PF06525.6 AJZ76187.1 - 1.4e-06 27.7 3.5 0.0012 18.1 0.1 2.9 2 2 0 2 2 2 2 Sulfocyanin (SoxE) Cu-oxidase_2 PF07731.9 AJZ76187.1 - 7.9e-05 22.1 0.0 0.24 10.8 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu_bind_like PF02298.12 AJZ76187.1 - 0.00012 21.8 0.0 0.076 12.8 0.0 2.6 2 1 0 2 2 2 2 Plastocyanin-like domain COX2 PF00116.15 AJZ76187.1 - 0.00039 20.2 0.1 0.57 10.0 0.0 2.8 2 2 0 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain Myosin_N PF02736.14 AJZ76187.1 - 0.06 13.0 2.0 12 5.6 0.1 3.0 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain PGBA_N PF15436.1 AJZ76187.1 - 0.12 11.6 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA N-terminal Glyco_transf_6 PF03414.8 AJZ76187.1 - 0.14 10.6 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 PPC PF04151.10 AJZ76187.1 - 0.15 13.0 0.8 3.9 8.5 0.1 2.5 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain COX15-CtaA PF02628.10 AJZ76188.1 - 1e-26 93.5 11.8 1.3e-26 93.1 8.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Endonuc_Holl PF10107.4 AJZ76189.1 - 2.9e-07 30.3 1.2 2e-05 24.3 0.1 2.2 1 1 0 2 2 2 2 Endonuclease related to archaeal Holliday junction resolvase CcmD PF04995.9 AJZ76189.1 - 0.042 13.5 0.6 0.089 12.5 0.4 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Wzz PF02706.10 AJZ76189.1 - 0.047 13.5 0.4 0.08 12.7 0.2 1.3 1 1 0 1 1 1 0 Chain length determinant protein Mt_ATP-synt_B PF05405.9 AJZ76189.1 - 0.057 12.8 0.1 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4381 PF14316.1 AJZ76189.1 - 0.14 12.2 0.3 0.2 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Lar_restr_allev PF14354.1 AJZ76190.1 - 0.00024 21.3 0.9 0.00049 20.3 0.6 1.5 1 1 0 1 1 1 1 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 AJZ76190.1 - 0.0017 17.4 1.4 0.21 10.8 0.2 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zf-H2C2_2 PF13465.1 AJZ76190.1 - 0.003 17.7 3.3 0.5 10.7 0.5 2.2 2 0 0 2 2 2 2 Zinc-finger double domain Zn-ribbon_8 PF09723.5 AJZ76190.1 - 0.0058 16.5 0.6 1.4 8.9 0.0 2.3 2 0 0 2 2 2 1 Zinc ribbon domain DUF1178 PF06676.6 AJZ76190.1 - 0.01 16.0 1.1 0.31 11.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) zf-RING_3 PF14369.1 AJZ76190.1 - 0.023 14.7 0.2 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 zinc-finger DUF164 PF02591.10 AJZ76190.1 - 0.058 13.2 0.4 4.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-Di19 PF05605.7 AJZ76190.1 - 0.067 13.3 0.3 1.9 8.6 0.0 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_2 PF13240.1 AJZ76190.1 - 0.076 12.5 1.4 0.73 9.4 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 AJZ76190.1 - 0.093 12.0 0.8 3.9 6.8 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 AJZ76190.1 - 0.11 12.1 0.5 0.64 9.7 0.1 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 AJZ76190.1 - 0.18 11.5 5.7 0.41 10.3 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS1 PF03811.8 AJZ76190.1 - 0.24 10.9 1.2 7.1 6.2 0.1 2.3 2 0 0 2 2 2 0 InsA N-terminal domain HypA PF01155.14 AJZ76190.1 - 0.26 10.9 1.0 0.94 9.1 0.7 1.8 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Elf1 PF05129.8 AJZ76190.1 - 0.42 10.3 2.4 6.5 6.5 0.1 2.2 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like DUF329 PF03884.9 AJZ76190.1 - 0.45 10.1 4.5 5.1 6.7 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF329) zf-H2C2 PF09337.5 AJZ76190.1 - 5.5 6.4 5.8 8.3 5.9 0.9 2.6 2 1 0 2 2 2 0 His(2)-Cys(2) zinc finger N6_Mtase PF02384.11 AJZ76191.1 - 5.8e-64 216.1 0.0 8.4e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.3 AJZ76191.1 - 2.9e-14 53.6 0.2 1.2e-11 45.2 0.1 2.7 1 1 0 1 1 1 1 HsdM N-terminal domain Methyltransf_26 PF13659.1 AJZ76191.1 - 2e-09 37.5 0.0 3.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 AJZ76191.1 - 4.6e-05 23.0 0.0 7.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.9 AJZ76191.1 - 0.00074 18.9 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Eco57I PF07669.6 AJZ76191.1 - 0.00084 19.6 0.0 0.0044 17.3 0.0 2.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase EcoEI_R_C PF08463.5 AJZ76192.1 - 3.8e-34 117.9 1.5 9.6e-34 116.5 1.0 1.7 1 0 0 1 1 1 1 EcoEI R protein C-terminal ResIII PF04851.10 AJZ76192.1 - 2.4e-33 115.5 0.0 5.9e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSDR_N PF04313.9 AJZ76192.1 - 4.5e-11 42.8 0.0 9.9e-10 38.4 0.0 2.8 1 1 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) DEAD PF00270.24 AJZ76192.1 - 3.2e-10 39.7 0.0 6.2e-08 32.3 0.0 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AJZ76192.1 - 1.1e-06 28.3 0.1 4.5e-06 26.4 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 AJZ76192.1 - 0.0015 17.7 0.0 0.0029 16.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein T2SE PF00437.15 AJZ76192.1 - 0.0059 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein CbiA PF01656.18 AJZ76192.1 - 0.01 15.2 0.0 1.5 8.1 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.12 AJZ76192.1 - 0.054 12.9 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD-helicase PF00580.16 AJZ76192.1 - 0.097 11.9 0.9 0.18 11.0 0.1 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 AJZ76192.1 - 0.16 11.7 0.1 0.47 10.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_4 PF04326.9 AJZ76193.1 - 3.8e-10 39.9 0.0 1e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 Divergent AAA domain MtrF PF09472.5 AJZ76195.1 - 0.14 11.4 2.4 0.18 11.0 1.3 1.5 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) LRR19-TM PF15176.1 AJZ76195.1 - 0.18 11.5 0.3 0.25 11.0 0.1 1.3 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain FUSC PF04632.7 AJZ76195.1 - 0.28 9.5 1.5 0.31 9.4 1.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3816 PF12822.2 AJZ76196.1 - 0.028 14.2 1.1 0.03 14.2 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) BacteriocIIc_cy PF12173.3 AJZ76196.1 - 0.087 12.8 0.5 0.11 12.5 0.4 1.1 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like DUF2254 PF10011.4 AJZ76196.1 - 0.11 10.9 1.2 0.11 10.9 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF912 PF06024.7 AJZ76196.1 - 0.16 12.0 0.5 0.23 11.5 0.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Baculo_11_kDa PF06143.6 AJZ76196.1 - 0.31 10.4 2.4 0.34 10.2 1.6 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF2116 PF09889.4 AJZ76197.1 - 0.0043 16.8 13.2 0.03 14.1 1.8 3.0 1 1 1 2 2 2 2 Uncharacterized protein containing a Zn-ribbon (DUF2116) TF_Zn_Ribbon PF08271.7 AJZ76197.1 - 0.0078 15.5 2.7 0.14 11.5 0.8 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding C1_1 PF00130.17 AJZ76197.1 - 0.013 15.2 2.6 0.079 12.7 0.2 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3270 PF11674.3 AJZ76197.1 - 0.026 14.5 0.1 0.035 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) DZR PF12773.2 AJZ76197.1 - 0.033 13.9 6.1 1.8 8.4 4.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon DUF1677 PF07911.8 AJZ76197.1 - 0.058 13.5 0.7 0.067 13.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Vps39_2 PF10367.4 AJZ76197.1 - 0.092 12.9 3.8 0.46 10.6 0.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Prok-RING_1 PF14446.1 AJZ76197.1 - 0.097 12.4 4.7 0.28 10.9 0.5 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE PF01363.16 AJZ76197.1 - 0.24 11.3 3.2 0.39 10.6 2.2 1.3 1 0 0 1 1 1 0 FYVE zinc finger zf-CGNR PF11706.3 AJZ76197.1 - 0.95 9.0 4.3 1.1 8.7 1.3 2.1 2 0 0 2 2 2 0 CGNR zinc finger DUF4428 PF14471.1 AJZ76197.1 - 0.98 9.2 7.6 5.6 6.8 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) CIAPIN1 PF05093.8 AJZ76197.1 - 1.3 9.1 8.6 2 8.5 2.4 2.1 1 1 1 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis AAA_10 PF12846.2 AJZ76198.1 - 2.9e-14 53.2 0.3 5.9e-11 42.3 0.0 2.3 1 1 1 2 2 2 2 AAA-like domain DEAD PF00270.24 AJZ76198.1 - 1.9e-09 37.2 1.0 1e-08 34.8 0.7 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.4 AJZ76198.1 - 2.7e-08 32.8 0.3 3e-05 22.8 0.1 2.2 1 1 1 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.10 AJZ76198.1 - 2.2e-07 30.8 2.3 1e-06 28.7 1.5 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AJZ76198.1 - 2.6e-07 30.8 0.1 4.9e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AJZ76198.1 - 9.1e-07 28.6 0.1 3e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 AJZ76198.1 - 9.6e-07 28.0 0.2 1.5e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Pox_A32 PF04665.7 AJZ76198.1 - 1.8e-05 24.1 0.5 5.1e-05 22.6 0.3 1.7 1 1 0 1 1 1 1 Poxvirus A32 protein Arg_repressor PF01316.16 AJZ76198.1 - 4.5e-05 22.9 0.1 0.00012 21.6 0.0 1.7 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain FUR PF01475.14 AJZ76198.1 - 4.5e-05 23.3 0.0 0.00014 21.8 0.0 1.8 1 0 0 1 1 1 1 Ferric uptake regulator family DUF87 PF01935.12 AJZ76198.1 - 6.8e-05 22.8 1.3 0.00019 21.3 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 HTH_Tnp_Tc3_2 PF01498.13 AJZ76198.1 - 0.00015 21.7 0.1 0.00039 20.4 0.0 1.6 1 0 0 1 1 1 1 Transposase T2SE PF00437.15 AJZ76198.1 - 0.00018 20.5 0.1 0.00034 19.5 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Zot PF05707.7 AJZ76198.1 - 0.00031 20.2 0.6 0.00082 18.8 0.4 1.6 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_18 PF13238.1 AJZ76198.1 - 0.00038 20.7 2.1 0.00038 20.7 0.5 1.7 2 0 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 AJZ76198.1 - 0.0019 17.9 1.3 0.0079 15.9 0.2 2.1 2 0 0 2 2 2 1 Archaeal ATPase HTH_20 PF12840.2 AJZ76198.1 - 0.004 16.9 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.7 AJZ76198.1 - 0.0061 16.0 0.1 0.017 14.6 0.1 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain AAA_19 PF13245.1 AJZ76198.1 - 0.0066 16.1 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF853 PF05872.7 AJZ76198.1 - 0.0093 14.3 1.3 0.44 8.8 0.1 2.4 1 1 0 2 2 2 1 Bacterial protein of unknown function (DUF853) KTI12 PF08433.5 AJZ76198.1 - 0.01 15.0 0.1 0.064 12.4 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 AJZ76198.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 AJZ76198.1 - 0.014 15.5 0.1 0.039 14.1 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.21 AJZ76198.1 - 0.018 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MarR PF01047.17 AJZ76198.1 - 0.028 14.1 0.0 0.078 12.6 0.0 1.7 1 1 0 1 1 1 0 MarR family ABC_tran PF00005.22 AJZ76198.1 - 0.033 14.4 0.0 0.092 13.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter HTH_12 PF08461.5 AJZ76198.1 - 0.036 13.8 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Pox_TAA1 PF03295.9 AJZ76198.1 - 0.044 13.4 0.1 0.2 11.3 0.0 2.1 2 0 0 2 2 1 0 Poxvirus trans-activator protein A1 C-terminal NTPase_1 PF03266.10 AJZ76198.1 - 0.048 13.3 0.7 0.13 11.9 0.5 1.7 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.12 AJZ76198.1 - 0.058 12.8 0.1 0.5 9.7 0.0 2.3 2 1 0 2 2 2 0 IstB-like ATP binding protein HTH_24 PF13412.1 AJZ76198.1 - 0.062 12.6 0.4 0.19 11.1 0.3 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Mg_chelatase PF01078.16 AJZ76198.1 - 0.085 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.14 AJZ76198.1 - 0.091 12.1 1.9 0.18 11.2 0.5 2.0 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ubiquitin_3 PF14836.1 AJZ76198.1 - 0.094 12.3 0.1 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain AAA PF00004.24 AJZ76198.1 - 0.096 12.8 0.1 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AJZ76198.1 - 0.14 13.0 2.1 0.19 12.5 0.7 1.9 2 1 0 2 2 1 0 AAA domain NACHT PF05729.7 AJZ76198.1 - 0.14 11.8 0.3 0.28 10.8 0.2 1.5 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.17 AJZ76198.1 - 0.18 11.2 1.5 0.51 9.7 0.4 2.2 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain TFIIIC_delta PF12657.2 AJZ76201.1 - 0.16 11.6 0.3 0.24 11.0 0.2 1.3 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term HARE-HTH PF05066.8 AJZ76202.1 - 0.022 15.0 0.1 0.025 14.9 0.1 1.2 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain DUF4373 PF14297.1 AJZ76202.1 - 0.089 13.0 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4373) TAF PF02969.12 AJZ76202.1 - 0.12 12.2 0.3 2.4 8.1 0.2 2.0 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) AAA_10 PF12846.2 AJZ76203.1 - 9e-20 71.3 0.2 4.2e-17 62.5 0.1 2.5 1 1 0 1 1 1 1 AAA-like domain DUF853 PF05872.7 AJZ76203.1 - 7.6e-08 31.1 0.0 0.0011 17.4 0.0 2.3 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) DUF87 PF01935.12 AJZ76203.1 - 1.1e-05 25.3 2.6 0.00022 21.1 0.0 3.4 4 1 0 4 4 4 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 AJZ76203.1 - 0.0047 16.4 0.0 0.026 13.9 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 AJZ76203.1 - 0.0047 15.5 0.0 0.12 10.9 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 AJZ76203.1 - 0.0066 16.5 0.0 0.67 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AJZ76203.1 - 0.016 16.0 0.7 0.24 12.2 0.0 3.2 4 0 0 4 4 4 0 AAA domain ResIII PF04851.10 AJZ76203.1 - 0.019 14.7 0.2 0.45 10.3 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit LexA_DNA_bind PF01726.11 AJZ76203.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 LexA DNA binding domain Zot PF05707.7 AJZ76203.1 - 0.077 12.4 0.0 0.86 9.0 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Syntaxin-6_N PF09177.6 AJZ76203.1 - 0.53 10.7 4.5 9.9 6.6 1.1 3.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Use1 PF09753.4 AJZ76204.1 - 0.016 14.6 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 EMP24_GP25L PF01105.19 AJZ76205.1 - 0.0023 17.6 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Bac_luciferase PF00296.15 AJZ76205.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase TrmB PF01978.14 AJZ76206.1 - 0.038 13.6 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.4 AJZ76206.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DUF457 PF04307.9 AJZ76207.1 - 1.1e-08 34.5 9.4 1.3e-08 34.3 6.5 1.1 1 0 0 1 1 1 1 Predicted membrane-bound metal-dependent hydrolase (DUF457) AzlD PF05437.7 AJZ76207.1 - 1.7 8.6 10.5 0.055 13.4 1.8 2.3 1 1 2 3 3 3 0 Branched-chain amino acid transport protein (AzlD) Thioredoxin PF00085.15 AJZ76208.1 - 1e-26 92.6 0.4 1.2e-26 92.4 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AJZ76208.1 - 5.6e-12 45.8 0.3 2.6e-11 43.7 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AJZ76208.1 - 0.00011 22.2 0.2 0.0003 20.8 0.1 1.6 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 AJZ76208.1 - 0.00023 20.8 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Redoxin PF08534.5 AJZ76208.1 - 0.002 17.6 0.1 0.0021 17.6 0.1 1.2 1 0 0 1 1 1 1 Redoxin DUF953 PF06110.6 AJZ76208.1 - 0.0037 16.6 0.1 0.0059 16.0 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) AhpC-TSA PF00578.16 AJZ76208.1 - 0.0078 15.9 0.2 0.022 14.4 0.2 1.6 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 AJZ76208.1 - 0.01 15.8 0.3 0.02 14.9 0.2 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 AJZ76208.1 - 0.014 14.9 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DUF836 PF05768.9 AJZ76208.1 - 0.014 15.6 0.0 0.022 15.0 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) HyaE PF07449.6 AJZ76208.1 - 0.042 13.7 0.0 0.075 12.9 0.0 1.5 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 AJZ76208.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin DSBA PF01323.15 AJZ76208.1 - 0.12 11.8 0.9 1.4 8.3 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain PMSR PF01625.16 AJZ76209.1 - 2.8e-65 218.9 0.3 3.2e-65 218.7 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Ferritin PF00210.19 AJZ76210.1 - 3.8e-29 101.2 0.9 4.2e-29 101.1 0.6 1.0 1 0 0 1 1 1 1 Ferritin-like domain DUF1241 PF06840.6 AJZ76210.1 - 0.0079 15.4 0.2 0.032 13.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) Syntaxin PF00804.20 AJZ76210.1 - 0.03 14.5 1.1 0.042 14.0 0.8 1.3 1 1 0 1 1 1 0 Syntaxin Osmo_CC PF08946.5 AJZ76210.1 - 0.1 12.6 0.9 0.23 11.5 0.2 1.9 2 0 0 2 2 2 0 Osmosensory transporter coiled coil GP41 PF00517.12 AJZ76210.1 - 0.12 11.9 0.2 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 Retroviral envelope protein DUF2024 PF09630.5 AJZ76211.1 - 6.8e-36 121.8 1.2 8.2e-36 121.5 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) Haem_bd PF14376.1 AJZ76211.1 - 0.11 12.1 0.1 0.14 11.7 0.1 1.3 1 1 0 1 1 1 0 Haem-binding domain Pyr_redox_2 PF07992.9 AJZ76212.1 - 3e-25 89.2 2.7 2.9e-24 86.0 1.9 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AJZ76212.1 - 3.3e-15 56.2 5.1 1.4e-12 47.8 0.2 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AJZ76212.1 - 1.4e-14 54.6 0.9 1.3e-07 31.8 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 AJZ76212.1 - 4.1e-09 36.6 0.6 0.00011 22.3 0.1 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding DAO PF01266.19 AJZ76212.1 - 7e-06 25.1 10.4 0.0091 14.9 0.0 3.4 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AJZ76212.1 - 3.2e-05 23.1 0.2 0.00055 19.0 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 AJZ76212.1 - 0.00015 20.9 0.7 0.13 11.2 0.1 3.3 3 0 0 3 3 3 2 Thi4 family FAD_binding_2 PF00890.19 AJZ76212.1 - 0.00053 18.9 3.9 0.0016 17.3 1.3 2.7 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 AJZ76212.1 - 0.00061 19.7 0.3 0.0026 17.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 AJZ76212.1 - 0.0009 18.1 6.1 0.14 10.9 0.0 4.0 3 1 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.9 AJZ76212.1 - 0.0019 16.7 3.5 0.12 10.8 0.1 3.4 4 0 0 4 4 4 2 HI0933-like protein NAD_binding_9 PF13454.1 AJZ76212.1 - 0.0071 16.1 1.4 2.9 7.6 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 AJZ76212.1 - 0.031 14.3 2.2 0.36 10.9 0.1 2.9 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 AJZ76212.1 - 0.12 11.2 1.4 14 4.4 0.0 3.3 3 1 1 4 4 4 0 Lycopene cyclase protein BLOC1_2 PF10046.4 AJZ76213.1 - 5.6e-05 23.2 2.3 7.5e-05 22.8 1.6 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Chlamy_scaf PF09675.5 AJZ76213.1 - 0.025 14.5 0.1 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) RHH_1 PF01402.16 AJZ76214.1 - 0.025 14.4 0.2 0.097 12.6 0.0 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HicB PF05534.7 AJZ76214.1 - 0.027 14.0 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 HicB family EST1 PF10374.4 AJZ76214.1 - 0.048 13.6 0.1 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Telomerase activating protein Est1 SelR PF01641.13 AJZ76215.1 - 4.5e-52 174.9 0.2 5.2e-52 174.7 0.1 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 AJZ76215.1 - 0.0046 16.9 0.1 0.0086 16.0 0.0 1.5 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_Tnp_IS1595 PF12760.2 AJZ76215.1 - 0.025 14.4 1.7 0.37 10.6 0.2 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF678 PF05077.7 AJZ76215.1 - 0.027 14.4 0.2 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DnaJ_CXXCXGXG PF00684.14 AJZ76215.1 - 0.039 13.9 0.3 4.3 7.4 0.0 2.2 2 0 0 2 2 2 0 DnaJ central domain DZR PF12773.2 AJZ76215.1 - 0.091 12.5 0.5 0.41 10.4 0.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-tcix PF14952.1 AJZ76215.1 - 0.094 12.0 1.0 0.51 9.7 0.1 2.2 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding GCC2_GCC3 PF07699.8 AJZ76215.1 - 1.5 8.4 4.9 2.9 7.5 0.6 2.3 2 0 0 2 2 2 0 GCC2 and GCC3 NAD_binding_6 PF08030.7 AJZ76217.1 - 0.03 14.2 0.5 0.042 13.7 0.4 1.2 1 0 0 1 1 1 0 Ferric reductase NAD binding domain SPOB_a PF14689.1 AJZ76217.1 - 0.15 11.6 2.0 0.15 11.6 0.0 2.0 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain CHD5 PF04420.9 AJZ76217.1 - 0.16 11.6 5.5 1.2 8.8 0.1 3.0 3 0 0 3 3 3 0 CHD5-like protein Reticulon PF02453.12 AJZ76217.1 - 1.5 8.4 6.9 1.2 8.6 0.0 3.1 4 0 0 4 4 4 0 Reticulon DUF1312 PF07009.6 AJZ76217.1 - 1.7 8.4 9.1 0.85 9.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1312) Pentapeptide PF00805.17 AJZ76218.1 - 3.4e-83 271.9 94.7 3.2e-13 48.5 1.8 13.9 3 3 10 14 14 14 14 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 AJZ76218.1 - 8.9e-56 185.6 43.0 4e-12 45.7 0.3 8.5 1 1 7 8 8 8 8 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 AJZ76218.1 - 4.9e-46 154.3 31.9 6.9e-08 32.2 0.3 11.9 2 2 10 13 13 13 12 Pentapeptide repeats (9 copies) CfAFP PF05264.6 AJZ76218.1 - 1e-05 25.2 12.8 1.5 8.5 0.2 5.7 1 1 5 7 7 7 4 Choristoneura fumiferana antifreeze protein (CfAFP) Novirhabdo_Nv PF05554.6 AJZ76218.1 - 0.077 12.5 10.2 8.7 5.8 0.2 5.0 2 1 1 4 4 4 0 Viral hemorrhagic septicemia virus non-virion protein DUF285 PF03382.9 AJZ76218.1 - 5.1 6.6 20.3 6 6.4 1.3 4.6 2 1 3 6 6 6 0 Mycoplasma protein of unknown function, DUF285 Flavodoxin_5 PF12724.2 AJZ76219.1 - 0.092 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Flavodoxin domain CemA PF03040.9 AJZ76219.1 - 0.12 11.9 1.0 0.12 11.9 0.7 1.0 1 0 0 1 1 1 0 CemA family PhoU PF01895.14 AJZ76220.1 - 7e-18 64.8 3.8 1.9e-08 34.6 1.6 2.1 2 0 0 2 2 2 2 PhoU domain BPD_transp_1 PF00528.17 AJZ76221.1 - 3.4e-17 62.5 20.4 3.4e-17 62.5 14.1 2.0 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3593 PF12159.3 AJZ76221.1 - 5.7 6.7 6.7 1.1 9.0 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3593) PhoU PF01895.14 AJZ76222.1 - 5.1e-17 62.0 13.7 4.7e-14 52.5 3.1 2.6 2 0 0 2 2 2 2 PhoU domain Antitoxin-MazE PF04014.13 AJZ76222.1 - 6e-06 25.8 0.0 1.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Antidote-toxin recognition MazE Methyltransf_11 PF08241.7 AJZ76224.1 - 3.5e-14 53.0 0.0 6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJZ76224.1 - 1.3e-11 44.2 0.1 1.8e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJZ76224.1 - 8.9e-10 38.8 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJZ76224.1 - 5.8e-08 32.6 0.0 2.5e-07 30.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJZ76224.1 - 3.5e-07 30.6 0.0 6.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJZ76224.1 - 8.1e-05 23.1 0.0 0.00013 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 AJZ76224.1 - 0.0012 18.1 0.7 0.03 13.6 0.2 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.6 AJZ76224.1 - 0.0021 17.5 0.0 0.0027 17.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 AJZ76224.1 - 0.007 15.4 0.1 0.0087 15.2 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AJZ76224.1 - 0.0097 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 AJZ76224.1 - 0.028 13.8 0.0 0.05 12.9 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.9 AJZ76224.1 - 0.043 13.2 0.1 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain TPMT PF05724.6 AJZ76224.1 - 0.069 12.5 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Fe-S_assembly PF04384.8 AJZ76224.1 - 0.18 12.1 0.9 0.69 10.3 0.1 2.4 3 1 0 3 3 3 0 Iron-sulphur cluster assembly Aminotran_4 PF01063.14 AJZ76225.1 - 1.4e-46 158.8 0.0 1.6e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV DUF1634 PF07843.6 AJZ76226.1 - 0.0048 16.4 0.1 0.0053 16.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1634) AA_kinase PF00696.23 AJZ76227.1 - 8.1e-23 81.2 0.2 6e-22 78.3 0.1 2.1 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.20 AJZ76227.1 - 0.061 12.8 1.0 0.15 11.5 0.7 1.6 1 0 0 1 1 1 0 ACT domain Glyco_tran_28_C PF04101.11 AJZ76228.1 - 1.6e-14 53.9 0.3 4.2e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 AJZ76228.1 - 2e-14 53.5 0.0 2.7e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 Laminin_G_3 PF13385.1 AJZ76229.1 - 4.5e-13 49.7 0.3 5.9e-13 49.3 0.2 1.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF900 PF05990.7 AJZ76230.1 - 1.7e-14 53.7 0.1 2.8e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 AJZ76230.1 - 5.8e-06 26.1 0.2 3.1e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AJZ76230.1 - 0.00011 22.2 0.1 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 AJZ76230.1 - 0.0004 19.4 0.1 0.00075 18.5 0.1 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 AJZ76230.1 - 0.0015 18.1 0.2 0.0029 17.2 0.2 1.4 1 0 0 1 1 1 1 PGAP1-like protein NHL PF01436.16 AJZ76230.1 - 0.0027 17.5 0.2 0.035 14.0 0.1 2.7 2 0 0 2 2 2 1 NHL repeat Lipase_2 PF01674.13 AJZ76230.1 - 0.0029 16.9 0.1 0.0076 15.5 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 2) Cutinase PF01083.17 AJZ76230.1 - 0.021 14.5 0.9 0.038 13.7 0.0 1.8 2 0 0 2 2 2 0 Cutinase SBBP PF06739.6 AJZ76230.1 - 0.55 10.0 4.1 4.1 7.2 0.0 3.7 4 0 0 4 4 4 0 Beta-propeller repeat MarR_2 PF12802.2 AJZ76231.1 - 0.0035 16.9 0.0 0.0088 15.6 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 AJZ76231.1 - 0.017 15.4 0.0 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_24 PF13412.1 AJZ76231.1 - 0.039 13.3 0.1 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 AJZ76231.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 MarR family DUF4423 PF14394.1 AJZ76231.1 - 0.061 12.8 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) DUF667 PF05018.8 AJZ76231.1 - 0.09 12.0 0.2 0.18 10.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF667) Guanylate_cyc PF00211.15 AJZ76233.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Calx-beta PF03160.9 AJZ76234.1 - 3.3e-11 43.0 0.0 1.2e-08 34.7 0.0 2.9 2 0 0 2 2 2 2 Calx-beta domain TSP_3 PF02412.13 AJZ76234.1 - 6.6e-08 31.9 19.2 3e-07 29.8 5.3 4.9 4 1 0 4 4 4 2 Thrombospondin type 3 repeat LBR_tudor PF09465.5 AJZ76234.1 - 2e-05 24.1 0.1 0.044 13.4 0.0 2.7 2 0 0 2 2 2 2 Lamin-B receptor of TUDOR domain Calx-beta PF03160.9 AJZ76236.1 - 5.1e-25 87.3 17.4 0.029 14.3 0.0 12.8 13 4 0 13 13 13 7 Calx-beta domain HYR PF02494.11 AJZ76236.1 - 8.8e-05 22.4 29.8 2.9 7.9 0.3 7.1 9 0 0 9 9 9 5 HYR domain FixG_C PF11614.3 AJZ76236.1 - 0.016 15.3 8.3 1e+02 3.0 0.0 7.1 8 0 0 8 8 8 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF3924 PF13062.1 AJZ76236.1 - 0.018 14.8 10.4 82 3.1 0.0 6.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3924) DUF2341 PF10102.4 AJZ76236.1 - 0.092 12.9 19.1 45 4.2 0.1 6.3 6 0 0 6 6 6 0 Domain of unknown function (DUF2341) hEGF PF12661.2 AJZ76236.1 - 0.46 10.6 7.6 2.5e+02 2.1 0.0 5.3 5 0 0 5 5 5 0 Human growth factor-like EGF TFX_C PF14601.1 AJZ76236.1 - 0.46 10.2 2.8 13 5.6 0.0 4.7 6 0 0 6 6 6 0 DNA_binding protein, TFX, C-term Big_2 PF02368.13 AJZ76236.1 - 2.3 8.1 44.9 13 5.7 1.9 7.0 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 2) HALZ PF02183.13 AJZ76238.1 - 0.00012 21.6 1.3 0.047 13.4 0.0 2.2 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF4140 PF13600.1 AJZ76238.1 - 0.0024 18.3 1.8 0.17 12.3 0.1 2.0 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) Mito_fiss_reg PF05308.6 AJZ76238.1 - 0.0036 16.7 1.6 0.005 16.2 1.1 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator ATG16 PF08614.6 AJZ76238.1 - 0.0042 16.9 4.1 0.0048 16.7 2.9 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF3373 PF11853.3 AJZ76238.1 - 0.0052 15.3 4.7 0.031 12.8 2.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3373) Spectrin PF00435.16 AJZ76238.1 - 0.01 16.1 0.8 0.013 15.7 0.5 1.1 1 0 0 1 1 1 0 Spectrin repeat DUF2968 PF11180.3 AJZ76238.1 - 0.01 15.2 2.1 0.014 14.8 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Cast PF10174.4 AJZ76238.1 - 0.011 13.8 1.5 0.013 13.6 1.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF241 PF03087.9 AJZ76238.1 - 0.012 15.0 1.4 0.015 14.8 0.9 1.2 1 1 0 1 1 1 0 Arabidopsis protein of unknown function Leu_zip PF15294.1 AJZ76238.1 - 0.021 13.9 3.1 0.025 13.6 2.2 1.1 1 0 0 1 1 1 0 Leucine zipper FlaC_arch PF05377.6 AJZ76238.1 - 0.022 14.6 3.5 0.088 12.7 0.9 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Uds1 PF15456.1 AJZ76238.1 - 0.027 14.4 1.5 0.035 14.0 1.1 1.2 1 0 0 1 1 1 0 Up-regulated During Septation KCNQ_channel PF03520.9 AJZ76238.1 - 0.029 13.7 0.2 0.034 13.4 0.1 1.2 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel Bap31 PF05529.7 AJZ76238.1 - 0.029 13.8 4.9 0.056 12.8 3.4 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like TMF_TATA_bd PF12325.3 AJZ76238.1 - 0.03 14.0 2.5 0.052 13.2 1.7 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cob_adeno_trans PF01923.13 AJZ76238.1 - 0.036 13.8 1.0 0.11 12.3 0.7 1.7 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Mnd1 PF03962.10 AJZ76238.1 - 0.043 13.4 2.2 0.054 13.1 1.5 1.1 1 0 0 1 1 1 0 Mnd1 family YPEB PF14620.1 AJZ76238.1 - 0.049 12.6 2.7 0.061 12.3 1.8 1.0 1 0 0 1 1 1 0 YpeB sporulation DUF4391 PF14335.1 AJZ76238.1 - 0.05 12.9 0.5 5.6 6.2 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) IncA PF04156.9 AJZ76238.1 - 0.057 13.0 6.7 0.16 11.5 4.6 1.7 1 1 0 1 1 1 0 IncA protein DUF3138 PF11336.3 AJZ76238.1 - 0.061 11.4 1.1 0.062 11.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DASH_Spc34 PF08657.5 AJZ76238.1 - 0.065 12.8 2.1 0.077 12.6 1.5 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 Phage_GP20 PF06810.6 AJZ76238.1 - 0.073 12.5 6.2 0.49 9.8 1.6 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 bZIP_2 PF07716.10 AJZ76238.1 - 0.076 12.8 3.2 0.82 9.5 0.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Atg14 PF10186.4 AJZ76238.1 - 0.082 11.8 3.9 0.6 9.0 2.7 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HR1 PF02185.11 AJZ76238.1 - 0.089 12.5 7.9 1.3 8.8 1.5 2.1 1 1 1 2 2 2 0 Hr1 repeat FlxA PF14282.1 AJZ76238.1 - 0.091 12.7 12.5 36 4.3 8.7 2.2 1 1 0 1 1 1 0 FlxA-like protein Mitofilin PF09731.4 AJZ76238.1 - 0.1 11.2 4.4 0.14 10.7 3.1 1.3 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Prefoldin_2 PF01920.15 AJZ76238.1 - 0.11 12.2 2.3 1.1 9.0 0.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit K-box PF01486.12 AJZ76238.1 - 0.11 12.3 3.8 3.3 7.5 0.6 2.2 2 0 0 2 2 2 0 K-box region DUF2443 PF10398.4 AJZ76238.1 - 0.11 12.3 0.4 0.65 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) DUF2730 PF10805.3 AJZ76238.1 - 0.15 11.8 1.4 15 5.4 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF4200 PF13863.1 AJZ76238.1 - 0.15 11.9 1.3 3.6 7.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DivIC PF04977.10 AJZ76238.1 - 0.17 11.4 7.0 2.3 7.7 0.3 2.2 1 1 1 2 2 2 0 Septum formation initiator NPV_P10 PF05531.7 AJZ76238.1 - 0.17 12.1 6.1 48 4.2 4.2 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 AJZ76238.1 - 0.18 11.7 4.1 3.4 7.5 0.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1049 PF06305.6 AJZ76238.1 - 0.18 11.2 1.5 5.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Lectin_N PF03954.9 AJZ76238.1 - 0.19 11.0 6.2 0.36 10.2 4.3 1.4 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain RmuC PF02646.11 AJZ76238.1 - 0.2 10.4 3.0 0.43 9.3 0.1 2.0 1 1 1 2 2 2 0 RmuC family PspA_IM30 PF04012.7 AJZ76238.1 - 0.24 10.7 4.0 3 7.1 0.2 1.9 1 1 1 2 2 2 0 PspA/IM30 family V-SNARE PF05008.10 AJZ76238.1 - 0.28 11.3 2.6 8.3 6.6 0.3 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus TMV_coat PF00721.16 AJZ76238.1 - 0.28 11.0 2.1 0.34 10.8 1.5 1.1 1 0 0 1 1 1 0 Virus coat protein (TMV like) DMPK_coil PF08826.5 AJZ76238.1 - 0.28 11.0 3.5 2 8.3 1.1 2.2 2 1 0 2 2 2 0 DMPK coiled coil domain like Baculo_PEP_C PF04513.7 AJZ76238.1 - 0.29 10.9 7.0 0.45 10.3 4.9 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Viral_P18 PF04521.8 AJZ76238.1 - 0.29 10.5 3.0 1.4 8.3 0.2 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein GreA_GreB_N PF03449.10 AJZ76238.1 - 0.29 11.2 1.4 1.3 9.1 0.9 1.9 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal TMF_DNA_bd PF12329.3 AJZ76238.1 - 0.33 10.7 6.2 6.2 6.7 1.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding THOC7 PF05615.8 AJZ76238.1 - 0.37 11.0 5.0 1.8 8.8 3.5 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 COG5 PF10392.4 AJZ76238.1 - 0.38 10.7 3.2 2.5 8.0 1.0 2.0 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Sec2p PF06428.6 AJZ76238.1 - 0.48 10.2 5.4 4.9 7.0 0.2 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Vps53_N PF04100.7 AJZ76238.1 - 0.51 9.0 4.8 1.5 7.5 0.1 2.0 1 1 0 2 2 2 0 Vps53-like, N-terminal DASH_Hsk3 PF08227.6 AJZ76238.1 - 0.52 10.5 3.8 10 6.4 0.0 2.6 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like CENP-H PF05837.7 AJZ76238.1 - 0.53 10.4 4.5 0.85 9.8 3.1 1.3 1 1 0 1 1 1 0 Centromere protein H (CENP-H) SlyX PF04102.7 AJZ76238.1 - 0.97 9.8 4.4 9.5 6.6 0.3 2.3 1 1 1 2 2 2 0 SlyX Adeno_PIX PF03955.9 AJZ76238.1 - 1.6 9.2 5.2 10 6.7 0.5 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) 4HBT PF03061.17 AJZ76239.1 - 1.3e-15 57.2 0.0 1.8e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily PEP-utilisers_N PF05524.8 AJZ76239.1 - 0.0068 16.2 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal MaoC_dehydratas PF01575.14 AJZ76239.1 - 0.022 14.1 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 MaoC like domain Acyl_transf_3 PF01757.17 AJZ76241.1 - 0.63 8.8 29.0 0.75 8.5 7.8 2.5 1 1 2 3 3 3 0 Acyltransferase family Radical_SAM PF04055.16 AJZ76243.1 - 3.3e-18 66.3 0.0 1.1e-17 64.7 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily HTH_5 PF01022.15 AJZ76244.1 - 3e-06 26.7 0.3 9.8e-06 25.1 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 AJZ76244.1 - 2.1e-05 23.8 1.0 4.5e-05 22.7 0.4 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 AJZ76244.1 - 2.2e-05 24.1 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain B-block_TFIIIC PF04182.7 AJZ76244.1 - 0.00015 21.5 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TrmB PF01978.14 AJZ76244.1 - 0.002 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 AJZ76244.1 - 0.0026 17.3 0.1 0.0047 16.5 0.1 1.5 1 0 0 1 1 1 1 HTH domain MarR PF01047.17 AJZ76244.1 - 0.013 15.1 0.1 0.029 14.0 0.0 1.5 2 0 0 2 2 2 0 MarR family MarR_2 PF12802.2 AJZ76244.1 - 0.051 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 MarR family IF2_N PF04760.10 AJZ76244.1 - 0.08 12.6 0.4 0.21 11.2 0.0 1.9 2 1 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region DUF3781 PF12636.2 AJZ76244.1 - 0.084 12.8 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) HTH_45 PF14947.1 AJZ76244.1 - 0.11 12.3 0.3 0.17 11.7 0.2 1.4 1 1 0 1 1 1 0 Winged helix-turn-helix TctB PF07331.6 AJZ76245.1 - 7.4 6.2 9.7 12 5.5 2.9 2.1 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DS PF01916.12 AJZ76246.1 - 1.6e-49 168.6 0.0 2e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DS PF01916.12 AJZ76247.1 - 1.8e-74 250.5 0.5 2.1e-74 250.3 0.4 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Usp PF00582.21 AJZ76248.1 - 4.6e-17 62.5 0.0 5.2e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family S6PP_C PF08472.5 AJZ76248.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal THF_DHG_CYH PF00763.18 AJZ76248.1 - 0.032 14.2 0.2 2 8.4 0.1 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain TPR_11 PF13414.1 AJZ76249.1 - 2.5e-68 225.6 36.1 6.3e-16 57.7 0.2 5.8 2 2 6 8 8 8 8 TPR repeat TPR_1 PF00515.23 AJZ76249.1 - 1.4e-64 211.2 24.8 5.2e-11 41.6 0.0 9.3 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 AJZ76249.1 - 1.3e-50 165.2 20.6 4e-09 35.6 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 AJZ76249.1 - 1.1e-44 146.8 17.3 2e-07 30.6 0.0 9.7 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 AJZ76249.1 - 1.2e-38 130.9 0.1 8.2e-08 32.7 0.0 5.3 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ76249.1 - 1.9e-36 121.0 23.3 1.7e-06 27.3 0.0 9.4 6 1 3 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ76249.1 - 2.5e-33 114.2 8.1 6.6e-07 29.5 0.0 6.1 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ76249.1 - 4.2e-32 109.9 13.4 7e-09 35.5 0.0 6.2 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 AJZ76249.1 - 2.3e-31 105.4 0.1 0.00028 21.2 0.0 9.0 2 2 7 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.1 AJZ76249.1 - 2.6e-23 79.8 7.2 0.029 14.1 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 AJZ76249.1 - 2.7e-19 69.1 12.2 2.4e-08 33.9 0.1 4.5 2 2 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AJZ76249.1 - 7.9e-19 66.7 9.0 0.035 14.5 0.0 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJZ76249.1 - 2.2e-17 62.6 16.2 0.0025 17.6 0.1 7.8 6 2 2 9 9 9 4 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 AJZ76249.1 - 7.9e-14 51.2 0.2 0.0082 15.9 0.1 4.7 2 1 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 AJZ76249.1 - 1.2e-09 37.7 7.7 5.1 7.1 0.0 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Coatomer_E PF04733.9 AJZ76249.1 - 4.2e-09 36.0 0.3 0.035 13.3 0.0 3.8 1 1 3 4 4 4 2 Coatomer epsilon subunit MIT PF04212.13 AJZ76249.1 - 1.7e-07 30.9 10.3 0.072 12.9 0.2 6.7 5 2 1 7 7 7 1 MIT (microtubule interacting and transport) domain NARP1 PF12569.3 AJZ76249.1 - 2.6e-07 29.7 7.3 0.065 11.9 0.2 4.7 1 1 6 7 7 7 4 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 AJZ76249.1 - 2.1e-06 27.7 1.5 3.2 7.9 0.1 5.2 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 AJZ76249.1 - 3e-06 26.5 0.3 0.067 12.2 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF3856 PF12968.2 AJZ76249.1 - 1e-05 25.3 1.6 0.099 12.4 0.0 5.0 3 3 1 4 4 4 1 Domain of Unknown Function (DUF3856) TOM20_plant PF06552.7 AJZ76249.1 - 2.8e-05 23.7 2.0 1.2 8.6 0.0 5.3 3 2 3 6 6 6 1 Plant specific mitochondrial import receptor subunit TOM20 PPR PF01535.15 AJZ76249.1 - 0.00041 20.1 4.1 13 6.0 0.0 5.9 6 0 0 6 6 6 0 PPR repeat TPR_5 PF12688.2 AJZ76249.1 - 0.0016 18.4 0.0 0.24 11.4 0.0 3.1 3 0 0 3 3 3 1 Tetratrico peptide repeat ChAPs PF09295.5 AJZ76249.1 - 0.002 16.9 0.0 0.48 9.1 0.0 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) RE_Eco47II PF09553.5 AJZ76249.1 - 0.0042 16.2 0.3 5.6 6.0 0.0 3.3 3 0 0 3 3 3 0 Eco47II restriction endonuclease Rapsyn_N PF10579.4 AJZ76249.1 - 0.0042 16.8 0.7 0.31 10.8 0.0 3.3 2 1 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region Alkyl_sulf_dimr PF14863.1 AJZ76249.1 - 0.011 15.9 0.2 25 5.0 0.0 3.8 2 1 2 4 4 4 0 Alkyl sulfatase dimerisation PPTA PF01239.17 AJZ76249.1 - 0.038 13.3 9.3 6.3 6.3 0.0 6.1 7 0 0 7 7 7 0 Protein prenyltransferase alpha subunit repeat 4HB_MCP_1 PF12729.2 AJZ76249.1 - 0.23 10.7 4.5 6.4 6.0 0.0 3.3 4 0 0 4 4 4 0 Four helix bundle sensory module for signal transduction TPR_3 PF07720.7 AJZ76249.1 - 7.4 6.4 13.6 2 8.3 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Rbsn PF11464.3 AJZ76250.1 - 0.024 14.2 0.6 0.27 10.8 0.0 2.4 2 0 0 2 2 2 0 Rabenosyn Rab binding domain DUF3378 PF11858.3 AJZ76250.1 - 0.059 13.4 0.4 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) YvbH_ext PF11724.3 AJZ76250.1 - 4.9 6.9 7.3 1.6 8.4 0.5 2.5 1 1 1 2 2 2 0 YvbH-like oligomerisation region Urease_gamma PF00547.13 AJZ76252.1 - 2.5e-13 49.9 0.1 3e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 Urease, gamma subunit NicO PF03824.11 AJZ76253.1 - 4.3e-12 45.9 18.2 1.3e-11 44.4 12.6 1.7 1 1 0 1 1 1 1 High-affinity nickel-transport protein DUF2721 PF11026.3 AJZ76253.1 - 0.98 9.0 9.7 0.66 9.6 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF21 PF01595.15 AJZ76253.1 - 1.3 8.2 6.0 0.19 10.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 DUF1469 PF07332.6 AJZ76253.1 - 2.9 7.6 6.2 34 4.2 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF2537 PF10801.3 AJZ76254.1 - 0.075 13.1 0.7 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) JSRP PF15312.1 AJZ76254.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein MHYT PF03707.11 AJZ76254.1 - 2.1 8.5 4.9 0.58 10.3 0.3 2.3 2 2 1 3 3 3 0 Bacterial signalling protein N terminal repeat RNase_H PF00075.19 AJZ76255.1 - 1.1e-13 51.6 0.0 1.4e-13 51.3 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 AJZ76255.1 - 3.8e-07 29.7 0.0 5.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like SCP-1 PF05483.7 AJZ76255.1 - 0.1 10.3 0.0 0.11 10.2 0.0 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) ATP-grasp_5 PF13549.1 AJZ76256.1 - 1.1e-79 266.7 0.8 1.1e-79 266.7 0.6 1.6 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.1 AJZ76256.1 - 2.5e-53 179.3 0.6 6.7e-53 177.9 0.4 1.8 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 AJZ76256.1 - 3.7e-24 85.1 0.2 1.4e-23 83.2 0.1 2.2 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.14 AJZ76256.1 - 4.8e-10 39.8 4.1 8.4e-10 39.0 0.9 2.8 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.5 AJZ76256.1 - 7.8e-05 22.1 0.5 0.00017 21.0 0.3 1.7 1 0 0 1 1 1 1 ATP-grasp domain dTMP_synthase PF02593.9 AJZ76256.1 - 0.0003 20.2 0.5 0.00083 18.7 0.1 1.9 2 0 0 2 2 2 1 Thymidylate synthase ATP-grasp_4 PF13535.1 AJZ76256.1 - 0.0015 18.2 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AJZ76256.1 - 0.034 13.4 0.2 0.07 12.3 0.1 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DZR PF12773.2 AJZ76257.1 - 0.0013 18.4 6.8 0.0043 16.8 4.8 1.7 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 AJZ76257.1 - 0.0026 17.1 3.4 0.0026 17.1 2.3 1.9 2 0 0 2 2 2 1 zinc-ribbon domain zf-B_box PF00643.19 AJZ76257.1 - 0.0064 16.3 2.5 0.0064 16.3 1.7 2.1 2 0 0 2 2 2 1 B-box zinc finger FYVE PF01363.16 AJZ76257.1 - 0.0076 16.1 4.2 0.0087 15.9 2.9 1.2 1 0 0 1 1 1 1 FYVE zinc finger zinc-ribbons_6 PF07191.7 AJZ76257.1 - 0.017 14.8 6.2 0.024 14.4 4.3 1.2 1 0 0 1 1 1 0 zinc-ribbons Auto_anti-p27 PF06677.7 AJZ76257.1 - 0.023 14.4 0.6 0.023 14.4 0.4 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-UBR PF02207.15 AJZ76257.1 - 0.032 13.9 5.5 0.043 13.5 3.8 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) PolC_DP2 PF03833.8 AJZ76257.1 - 0.08 10.5 2.1 0.077 10.6 1.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C2H2 PF00096.21 AJZ76257.1 - 0.15 12.4 7.8 6.6 7.2 0.3 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type Prok-RING_1 PF14446.1 AJZ76257.1 - 0.19 11.4 11.1 0.062 13.0 3.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-HIT PF04438.11 AJZ76257.1 - 0.23 11.1 7.3 0.27 10.9 1.8 2.1 2 0 0 2 2 2 0 HIT zinc finger TF_Zn_Ribbon PF08271.7 AJZ76257.1 - 0.3 10.4 9.4 0.52 9.6 2.7 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 AJZ76257.1 - 0.31 10.8 7.5 2.7 7.8 1.9 2.3 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 AJZ76257.1 - 0.37 10.7 0.6 0.37 10.7 0.4 3.0 1 1 1 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 AJZ76257.1 - 0.73 9.5 8.9 8.5 6.1 6.2 2.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain HypA PF01155.14 AJZ76257.1 - 0.78 9.4 7.9 5 6.8 5.7 1.8 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family GATA PF00320.22 AJZ76257.1 - 0.8 9.1 7.6 7.6 5.9 2.1 3.0 2 1 0 2 2 2 0 GATA zinc finger C1_3 PF07649.7 AJZ76257.1 - 0.85 9.7 5.9 0.29 11.1 1.2 2.1 2 0 0 2 2 2 0 C1-like domain UPF0547 PF10571.4 AJZ76257.1 - 1 9.1 6.0 0.23 11.1 1.1 2.2 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C3HC4_3 PF13920.1 AJZ76257.1 - 1.1 8.9 7.3 0.39 10.4 1.0 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 AJZ76257.1 - 1.3 8.7 10.2 0.1 12.3 2.4 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HYPF PF07503.7 AJZ76257.1 - 1.8 8.0 4.8 4.8 6.6 0.0 2.9 3 0 0 3 3 3 0 HypF finger zf-ribbon_3 PF13248.1 AJZ76257.1 - 2 7.7 9.1 24 4.3 0.1 2.9 1 1 1 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AJZ76257.1 - 2 8.1 8.5 9.6 6.0 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain C1_2 PF03107.11 AJZ76257.1 - 2.5 8.2 8.9 2.4 8.3 2.4 2.7 2 1 0 2 2 2 0 C1 domain zf-RING_5 PF14634.1 AJZ76257.1 - 2.7 7.7 8.0 1.6 8.5 1.9 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zinc_ribbon_5 PF13719.1 AJZ76257.1 - 2.8 7.5 9.3 4.5 6.9 0.2 3.2 2 1 1 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 AJZ76257.1 - 3.1 7.5 10.2 15 5.4 0.7 3.2 1 1 2 3 3 3 0 Nudix N-terminal YhfH PF14149.1 AJZ76257.1 - 4 7.3 9.4 6.1 6.7 0.2 2.8 1 1 2 3 3 3 0 YhfH-like protein zf-MYND PF01753.13 AJZ76257.1 - 4.1 7.3 8.9 22 4.9 6.2 2.0 1 1 0 1 1 1 0 MYND finger zf-RanBP PF00641.13 AJZ76257.1 - 4.6 6.4 8.7 19 4.4 0.1 3.0 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DUF983 PF06170.7 AJZ76257.1 - 4.7 7.3 6.1 15 5.7 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF983) A2L_zn_ribbon PF08792.5 AJZ76257.1 - 6.2 6.4 12.4 13 5.4 3.6 2.8 1 1 1 2 2 2 0 A2L zinc ribbon domain Fer4 PF00037.22 AJZ76257.1 - 8.4 6.1 9.9 2.2 8.0 0.2 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain DUF1610 PF07754.6 AJZ76257.1 - 9.8 6.3 8.2 4.6 7.4 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1610) HTH_5 PF01022.15 AJZ76258.1 - 1.5e-13 50.1 0.8 1.5e-13 50.1 0.6 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 AJZ76258.1 - 3.2e-08 33.2 0.1 4.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 AJZ76258.1 - 7.1e-08 31.7 0.2 1.1e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 AJZ76258.1 - 0.00032 20.3 0.1 0.00083 19.0 0.1 1.6 1 1 1 2 2 2 1 MarR family TFIIE_alpha PF02002.12 AJZ76258.1 - 0.00042 19.7 0.3 0.00055 19.4 0.2 1.2 1 0 0 1 1 1 1 TFIIE alpha subunit MarR_2 PF12802.2 AJZ76258.1 - 0.00045 19.8 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 AJZ76258.1 - 0.0012 18.5 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.1 AJZ76258.1 - 0.0014 18.6 0.1 0.0018 18.2 0.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain Arg_repressor PF01316.16 AJZ76258.1 - 0.004 16.6 1.0 0.0093 15.5 0.2 2.0 1 1 1 2 2 2 1 Arginine repressor, DNA binding domain Tn7_Tnp_TnsA_C PF08721.6 AJZ76258.1 - 0.0097 15.9 0.1 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 TnsA endonuclease C terminal HTH_IclR PF09339.5 AJZ76258.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain Penicillinase_R PF03965.11 AJZ76258.1 - 0.021 14.8 0.1 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor TBPIP PF07106.8 AJZ76258.1 - 0.041 13.4 0.1 0.046 13.2 0.1 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DltD_M PF04918.7 AJZ76258.1 - 0.11 12.7 0.1 0.12 12.5 0.1 1.0 1 0 0 1 1 1 0 DltD central region HTH_AsnC-type PF13404.1 AJZ76258.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.7 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain MIP PF00230.15 AJZ76259.1 - 1.6e-35 122.6 18.0 1.9e-35 122.4 12.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Adenine_glyco PF03352.8 AJZ76260.1 - 2.6e-81 271.4 0.2 3.1e-81 271.1 0.2 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase HpaB_N PF11794.3 AJZ76261.1 - 5.6e-87 291.4 0.0 1.9e-86 289.7 0.0 1.8 2 0 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.8 AJZ76261.1 - 2.1e-70 235.7 0.1 3.1e-70 235.1 0.1 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Amidohydro_1 PF01979.15 AJZ76262.1 - 9.4e-62 209.5 5.2 1.2e-61 209.2 3.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 AJZ76262.1 - 4.1e-51 172.1 4.9 8.6e-51 171.1 2.9 1.9 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Amidohydro_5 PF13594.1 AJZ76262.1 - 2.1e-07 30.6 4.6 2.1e-07 30.6 3.2 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 AJZ76262.1 - 0.00011 21.5 2.6 0.012 14.8 0.5 3.0 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 AJZ76262.1 - 0.0035 17.4 0.4 1.6 8.7 0.4 2.4 2 1 0 2 2 2 2 Amidohydrolase Urease_gamma PF00547.13 AJZ76263.1 - 1e-47 160.1 0.0 1.1e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Urease, gamma subunit UreE_N PF02814.10 AJZ76264.1 - 3e-07 29.8 0.0 5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain UreE_C PF05194.7 AJZ76264.1 - 0.0016 18.5 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 UreE urease accessory protein, C-terminal domain BCAS2 PF05700.6 AJZ76264.1 - 0.09 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) UreF PF01730.11 AJZ76265.1 - 3.5e-26 92.0 0.0 4.2e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 UreF Protoglobin PF11563.3 AJZ76265.1 - 0.08 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Protoglobin cobW PF02492.14 AJZ76266.1 - 8.9e-34 116.4 0.0 1e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 AJZ76266.1 - 1.4e-09 37.1 1.1 6.2e-09 35.0 0.8 1.8 1 1 0 1 1 1 1 ArgK protein MobB PF03205.9 AJZ76266.1 - 5.4e-07 29.4 0.0 9.1e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 AJZ76266.1 - 0.00036 20.0 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain NTPase_1 PF03266.10 AJZ76266.1 - 0.0019 17.9 0.1 0.0035 17.0 0.0 1.6 1 1 0 1 1 1 1 NTPase AAA_17 PF13207.1 AJZ76266.1 - 0.0035 18.1 0.2 0.014 16.2 0.1 1.9 1 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 AJZ76266.1 - 0.0054 16.1 0.2 1.1 8.6 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 AJZ76266.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AJZ76266.1 - 0.044 13.4 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain MipZ PF09140.6 AJZ76266.1 - 0.056 12.5 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ AAA_18 PF13238.1 AJZ76266.1 - 0.079 13.2 0.1 0.16 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AJZ76266.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_PrkA PF08298.6 AJZ76266.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain UreD PF01774.12 AJZ76267.1 - 1.1e-48 165.5 0.0 1.3e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein AdoHcyase PF05221.12 AJZ76267.1 - 0.047 12.6 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase Peptidase_S24 PF00717.18 AJZ76268.1 - 4.3e-09 35.8 1.9 4.5e-09 35.8 0.3 1.8 2 0 0 2 2 2 1 Peptidase S24-like SOR PF07682.6 AJZ76268.1 - 0.0076 14.8 0.0 0.013 14.0 0.0 1.3 1 0 0 1 1 1 1 Sulphur oxygenase reductase MscL PF01741.13 AJZ76268.1 - 0.016 15.3 1.2 0.017 15.2 0.0 1.6 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL DUF3299 PF11736.3 AJZ76268.1 - 0.02 14.7 0.2 0.041 13.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3299) DUF4330 PF14221.1 AJZ76268.1 - 0.16 11.8 2.1 11 5.8 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) TMEMspv1-c74-12 PF11044.3 AJZ76268.1 - 5.1 6.7 7.0 1.4 8.5 0.4 2.5 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PRC PF05239.11 AJZ76269.1 - 9.6e-05 22.1 0.4 0.0002 21.1 0.2 1.5 1 0 0 1 1 1 1 PRC-barrel domain DZR PF12773.2 AJZ76269.1 - 0.00071 19.3 12.2 0.021 14.6 2.5 2.4 2 1 0 2 2 2 2 Double zinc ribbon DUF3279 PF11682.3 AJZ76269.1 - 0.00074 19.0 1.4 6.9 6.2 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3279) zf-ribbon_3 PF13248.1 AJZ76269.1 - 0.00086 18.4 6.0 0.00086 18.4 4.1 2.7 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AJZ76269.1 - 0.0017 17.8 4.9 0.0017 17.8 3.4 2.9 3 0 0 3 3 3 1 zinc-ribbon domain Prim_Zn_Ribbon PF08273.7 AJZ76269.1 - 0.029 14.4 7.3 8.5 6.5 0.0 3.4 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase A2L_zn_ribbon PF08792.5 AJZ76269.1 - 0.056 12.9 0.1 0.056 12.9 0.0 3.8 3 1 0 3 3 2 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.7 AJZ76269.1 - 0.072 12.4 5.9 0.27 10.5 0.1 2.9 2 0 0 2 2 2 0 TFIIB zinc-binding zf-FCS PF06467.9 AJZ76269.1 - 0.1 12.2 6.1 4.1 7.1 0.1 3.4 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif RRN7 PF11781.3 AJZ76269.1 - 0.13 11.8 12.4 0.49 9.9 0.0 3.5 3 1 1 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 Gin PF10764.4 AJZ76269.1 - 2.9 7.6 7.6 10 5.9 0.2 2.8 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin GFA PF04828.9 AJZ76269.1 - 3 7.8 10.1 11 6.0 0.1 3.4 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 AJZ76269.1 - 9.2 6.1 9.6 17 5.3 2.4 3.2 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Thioredoxin PF00085.15 AJZ76270.1 - 1.5e-31 108.1 0.2 1.7e-31 107.9 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AJZ76270.1 - 8.9e-13 48.1 0.1 5.6e-09 36.0 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AJZ76270.1 - 2.9e-12 46.7 0.1 9.3e-12 45.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AJZ76270.1 - 1.7e-08 34.3 0.1 2.5e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 AJZ76270.1 - 2.1e-07 30.6 0.1 2.4e-07 30.4 0.1 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AJZ76270.1 - 6e-06 25.8 0.2 1.3e-05 24.8 0.1 1.5 1 1 0 1 1 1 1 Redoxin Thioredoxin_3 PF13192.1 AJZ76270.1 - 9.8e-06 25.2 0.1 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 AJZ76270.1 - 3.7e-05 23.3 0.0 4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 AJZ76270.1 - 0.00042 20.1 0.1 0.00096 19.0 0.0 1.6 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE TraF PF13728.1 AJZ76270.1 - 0.0026 17.2 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 AJZ76270.1 - 0.0029 17.6 0.1 0.023 14.6 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin DUF953 PF06110.6 AJZ76270.1 - 0.0032 16.9 0.4 0.0072 15.7 0.3 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) DUF836 PF05768.9 AJZ76270.1 - 0.018 15.2 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_6 PF13848.1 AJZ76270.1 - 0.071 12.9 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain zinc_ribbon_2 PF13240.1 AJZ76271.1 - 1e-06 28.0 2.3 1.5e-06 27.5 1.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 AJZ76271.1 - 1e-05 24.5 3.4 1.6e-05 23.8 2.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 AJZ76271.1 - 0.00015 21.5 1.7 0.00022 20.9 1.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon RRN7 PF11781.3 AJZ76271.1 - 0.095 12.2 2.3 0.19 11.2 1.6 1.5 1 1 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Sporozoite_P67 PF05642.6 AJZ76271.1 - 1.1 7.0 9.0 1.3 6.7 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nudix_N_2 PF14803.1 AJZ76271.1 - 4.9 6.9 5.3 4.4 7.0 0.5 2.2 2 0 0 2 2 2 0 Nudix N-terminal Pec_lyase_N PF04431.8 AJZ76272.1 - 0.044 13.8 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Pectate lyase, N terminus HasA PF06438.7 AJZ76272.1 - 0.065 12.6 0.4 0.13 11.6 0.2 1.5 1 1 1 2 2 2 0 Heme-binding protein A (HasA) DUF3347 PF11827.3 AJZ76272.1 - 0.099 12.6 7.4 0.11 12.4 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Spore_III_AB PF09548.5 AJZ76272.1 - 0.11 12.2 2.8 0.12 12.1 1.1 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) ERp29 PF07749.7 AJZ76272.1 - 0.32 11.6 4.6 5.1 7.7 0.3 2.2 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF2894 PF11445.3 AJZ76272.1 - 0.34 11.1 4.1 0.37 11.0 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) FadA PF09403.5 AJZ76272.1 - 0.41 10.6 5.7 1.7 8.6 3.9 2.0 1 1 0 1 1 1 0 Adhesion protein FadA FbpA PF05833.6 AJZ76272.1 - 0.76 8.2 7.1 2.2 6.7 4.9 1.7 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) FCH PF00611.18 AJZ76272.1 - 4.1 7.6 10.7 0.91 9.7 3.9 2.5 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain MbeD_MobD PF04899.7 AJZ76272.1 - 4.5 7.2 7.5 0.82 9.6 0.4 2.7 1 1 2 3 3 3 0 MbeD/MobD like zf-ribbon_3 PF13248.1 AJZ76273.1 - 1e-07 30.9 2.2 1.6e-07 30.2 1.5 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AJZ76273.1 - 1.3e-07 30.9 2.0 2.5e-07 29.9 1.4 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 AJZ76273.1 - 2e-05 24.3 1.5 3e-05 23.7 1.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.4 AJZ76273.1 - 0.00031 20.3 2.9 0.00086 18.9 2.1 1.6 1 1 1 2 2 2 2 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.1 AJZ76273.1 - 0.001 18.7 4.6 0.09 12.4 0.2 2.5 2 0 0 2 2 2 2 Nudix N-terminal C1_1 PF00130.17 AJZ76273.1 - 0.06 13.0 1.5 0.094 12.4 1.0 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GFA PF04828.9 AJZ76273.1 - 0.063 13.2 3.8 0.3 11.0 0.1 2.6 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme RRN7 PF11781.3 AJZ76273.1 - 0.07 12.6 0.7 5.6 6.5 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 YhfH PF14149.1 AJZ76273.1 - 0.095 12.5 5.1 1 9.1 0.2 2.3 1 1 1 2 2 2 0 YhfH-like protein zf-NADH-PPase PF09297.6 AJZ76273.1 - 0.099 12.1 3.8 1.7 8.2 2.6 2.2 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain RNA_POL_M_15KD PF02150.11 AJZ76273.1 - 0.1 12.3 3.9 2 8.1 0.2 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Prok-RING_1 PF14446.1 AJZ76273.1 - 0.14 11.9 2.0 0.2 11.4 1.4 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-tcix PF14952.1 AJZ76273.1 - 0.19 11.0 2.1 4.6 6.6 0.0 2.2 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-dskA_traR PF01258.12 AJZ76273.1 - 0.42 10.3 2.5 0.95 9.2 1.7 1.6 1 1 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger NOB1_Zn_bind PF08772.6 AJZ76273.1 - 0.52 10.1 6.6 2.5 7.9 0.4 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DNA_RNApol_7kD PF03604.8 AJZ76273.1 - 0.57 9.6 3.0 1.8 8.1 2.1 1.8 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit RecR PF02132.10 AJZ76273.1 - 0.66 9.4 3.3 3.3 7.2 0.2 2.1 1 1 1 2 2 2 0 RecR protein A2L_zn_ribbon PF08792.5 AJZ76273.1 - 1.2 8.6 5.2 3.8 7.1 0.1 2.7 3 0 0 3 3 3 0 A2L zinc ribbon domain E1-E2_ATPase PF00122.15 AJZ76274.1 - 1.8e-59 200.5 2.3 3.9e-59 199.4 0.4 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 AJZ76274.1 - 3.7e-48 164.7 3.0 5.6e-48 164.1 2.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 AJZ76274.1 - 2.8e-24 85.0 0.4 9.6e-14 51.2 0.1 2.8 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 AJZ76274.1 - 1.4e-16 61.2 0.1 7.3e-16 58.8 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AJZ76274.1 - 1.1e-05 25.0 7.8 4.3e-05 23.2 0.6 3.4 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 AJZ76274.1 - 0.002 17.9 0.7 0.071 12.9 0.0 3.4 3 1 1 4 4 4 1 Haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.1 AJZ76274.1 - 0.0036 17.4 0.3 0.1 12.7 0.1 2.9 3 0 0 3 3 3 1 CoA binding domain DUF3060 PF11259.3 AJZ76274.1 - 0.019 14.6 0.1 0.07 12.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) AdoHcyase PF05221.12 AJZ76275.1 - 2e-52 177.7 0.9 2.4e-52 177.5 0.6 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 AJZ76275.1 - 5.9e-50 169.2 1.7 1e-49 168.5 1.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 AJZ76275.1 - 3.9e-08 32.6 0.2 1.7e-07 30.5 0.2 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 AJZ76275.1 - 4.6e-05 22.8 0.2 8.8e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 AJZ76275.1 - 0.098 12.6 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.16 AJZ76275.1 - 0.1 12.1 0.5 0.49 9.9 0.2 2.2 2 1 1 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Amidohydro_4 PF13147.1 AJZ76276.1 - 1.6e-21 77.5 0.0 2.7e-21 76.8 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 AJZ76276.1 - 2.8e-11 43.0 1.1 2.8e-11 43.0 0.7 2.5 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 AJZ76276.1 - 9.8e-10 38.5 3.5 0.00015 21.5 0.0 2.6 2 2 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 AJZ76276.1 - 2.5e-06 26.9 0.0 0.00034 19.9 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase family TatD_DNase PF01026.16 AJZ76276.1 - 2.4e-05 23.7 0.1 0.0082 15.3 0.0 2.2 1 1 1 2 2 2 2 TatD related DNase AP_endonuc_2 PF01261.19 AJZ76276.1 - 0.0067 15.7 0.0 0.092 12.0 0.0 2.3 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Rib_5-P_isom_A PF06026.9 AJZ76277.1 - 3.9e-53 179.2 0.2 5.1e-53 178.9 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 AJZ76277.1 - 6.9e-05 22.5 0.3 0.03 13.9 0.0 2.3 1 1 1 2 2 2 2 DeoR C terminal sensor domain LSM PF01423.17 AJZ76279.1 - 1.7e-22 78.7 0.2 1.9e-22 78.5 0.2 1.0 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 AJZ76279.1 - 0.1 12.3 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Creatininase PF02633.9 AJZ76280.1 - 1.7e-57 194.2 0.0 2e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase Formyl_trans_N PF00551.14 AJZ76281.1 - 1.6e-43 148.3 0.2 2.6e-43 147.6 0.0 1.4 2 0 0 2 2 2 1 Formyl transferase ACT_6 PF13740.1 AJZ76281.1 - 6.7e-10 38.5 0.1 2e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.1 AJZ76281.1 - 0.0011 19.3 0.2 0.0037 17.5 0.1 2.0 2 0 0 2 2 2 1 ACT domain ACT PF01842.20 AJZ76281.1 - 0.028 13.9 0.4 0.085 12.3 0.0 2.1 2 0 0 2 2 2 0 ACT domain DUF457 PF04307.9 AJZ76282.1 - 0.00043 19.6 10.2 0.00088 18.6 7.1 1.5 1 0 0 1 1 1 1 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF2592 PF10766.4 AJZ76282.1 - 0.12 11.7 0.2 0.12 11.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2592) PGM_PMM_I PF02878.11 AJZ76283.1 - 6.6e-40 135.7 0.0 1.7e-39 134.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 AJZ76283.1 - 2.2e-25 89.0 0.0 8.8e-25 87.0 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 AJZ76283.1 - 7.9e-23 80.6 0.1 1.5e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 AJZ76283.1 - 2.1e-12 46.8 0.0 5.8e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain zf-met2 PF12907.2 AJZ76283.1 - 0.022 14.7 0.2 0.022 14.7 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding Ribosomal_L7Ae PF01248.21 AJZ76284.1 - 3.4e-26 90.5 0.1 4.2e-26 90.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3055 PF11256.3 AJZ76284.1 - 0.077 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3055) Ribosomal_S28e PF01200.13 AJZ76285.1 - 6.3e-29 99.5 3.8 6.6e-29 99.4 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e KOW PF00467.24 AJZ76285.1 - 0.11 12.2 0.5 0.3 10.8 0.3 1.8 1 0 0 1 1 1 0 KOW motif Ribosomal_L24e PF01246.15 AJZ76286.1 - 5.9e-18 64.5 0.4 6.6e-18 64.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 AJZ76286.1 - 0.0025 17.4 1.0 0.0044 16.6 0.7 1.4 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif DUF2256 PF10013.4 AJZ76286.1 - 0.0041 16.8 4.4 5.3 6.8 0.1 3.1 3 0 0 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2256) DUF581 PF04570.9 AJZ76286.1 - 0.14 11.4 0.1 0.27 10.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF581) NDK PF00334.14 AJZ76287.1 - 1.3e-51 173.9 0.1 1.4e-51 173.7 0.1 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Thioredoxin PF00085.15 AJZ76288.1 - 1.5e-29 101.7 0.0 2.5e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AJZ76288.1 - 3.1e-10 40.2 0.4 2.7e-09 37.2 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 AJZ76288.1 - 1e-08 34.8 0.1 1.2e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AJZ76288.1 - 1.6e-08 34.5 0.6 2.4e-06 27.5 0.0 2.5 2 1 1 3 3 3 2 Thioredoxin-like Redoxin PF08534.5 AJZ76288.1 - 5e-06 26.1 0.1 3.4e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 Redoxin TraF PF13728.1 AJZ76288.1 - 8e-05 22.2 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 AJZ76288.1 - 0.00011 22.1 0.4 0.00018 21.4 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 AJZ76288.1 - 0.00017 21.2 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 AJZ76288.1 - 0.0002 21.0 0.1 0.00041 20.0 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.11 AJZ76288.1 - 0.0004 19.2 0.0 0.00047 18.9 0.0 1.1 1 0 0 1 1 1 1 Phosducin HyaE PF07449.6 AJZ76288.1 - 0.018 14.8 0.1 0.045 13.6 0.0 1.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.1 AJZ76288.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 AJZ76288.1 - 0.023 14.9 0.0 0.065 13.5 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) EF-1_beta_acid PF10587.4 AJZ76288.1 - 0.042 14.0 0.8 0.078 13.1 0.6 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region tRNA_bind PF01588.15 AJZ76288.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative tRNA binding domain Glutaredoxin PF00462.19 AJZ76288.1 - 0.098 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_4 PF13462.1 AJZ76288.1 - 0.26 11.2 1.2 0.73 9.8 0.8 1.9 1 1 0 1 1 1 0 Thioredoxin DSBA PF01323.15 AJZ76288.1 - 2.6 7.5 5.1 7.5 6.0 0.1 2.5 2 1 1 3 3 3 0 DSBA-like thioredoxin domain Archease PF01951.11 AJZ76289.1 - 6.2e-36 123.3 3.6 6.9e-36 123.2 2.5 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) tRNA-synt_His PF13393.1 AJZ76290.1 - 1.6e-44 152.2 0.0 1.9e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 AJZ76290.1 - 2.5e-16 59.7 0.2 4.1e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AJZ76290.1 - 3.4e-09 36.5 0.0 1.1e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2d PF01409.15 AJZ76290.1 - 0.001 18.2 0.1 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) TA0956 PF11513.3 AJZ76290.1 - 0.045 13.8 1.9 5 7.2 0.6 2.8 2 1 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 eIF-6 PF01912.13 AJZ76291.1 - 4.7e-66 221.6 0.9 5.5e-66 221.4 0.6 1.0 1 0 0 1 1 1 1 eIF-6 family Fer4 PF00037.22 AJZ76292.1 - 2.2e-09 36.5 11.7 5.3e-06 25.8 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 AJZ76292.1 - 1.9e-08 34.2 1.0 0.0015 18.5 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 AJZ76292.1 - 2.3e-08 34.2 26.5 2e-05 24.8 6.6 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.1 AJZ76292.1 - 6.4e-07 29.5 5.5 2.8e-06 27.4 3.8 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AJZ76292.1 - 1.7e-06 27.7 17.6 3e-05 23.7 5.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 AJZ76292.1 - 1.9e-06 27.4 11.6 0.003 17.3 2.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 AJZ76292.1 - 2.3e-06 28.2 2.4 0.0015 19.1 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 AJZ76292.1 - 2.6e-06 27.1 4.0 0.0037 17.0 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 AJZ76292.1 - 4e-06 26.4 11.7 0.0062 16.3 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 AJZ76292.1 - 5.4e-06 26.8 4.0 0.0064 17.0 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 AJZ76292.1 - 1.3e-05 25.4 8.5 4.2e-05 23.8 4.0 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 AJZ76292.1 - 1.5e-05 24.8 5.1 0.025 14.9 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 AJZ76292.1 - 0.00039 20.7 8.5 0.068 13.5 0.5 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_17 PF13534.1 AJZ76292.1 - 0.00047 20.4 5.8 0.03 14.6 5.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_11 PF13247.1 AJZ76292.1 - 0.012 15.5 1.1 2.5 8.0 0.1 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.2 AJZ76292.1 - 0.072 13.6 15.8 0.2 12.2 1.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain DNA_pol3_delta2 PF13177.1 AJZ76293.1 - 3.8e-17 62.4 0.4 6.5e-15 55.1 0.3 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 AJZ76293.1 - 2.2e-13 50.5 0.5 5.6e-13 49.2 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 AJZ76293.1 - 1.6e-11 44.0 1.7 2.2e-11 43.5 0.3 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 AJZ76293.1 - 4.7e-09 35.4 1.4 0.0015 17.2 0.0 2.5 1 1 2 3 3 3 2 Rad17 cell cycle checkpoint protein DNA_pol3_delta PF06144.8 AJZ76293.1 - 2.1e-06 27.3 0.5 6.4e-06 25.7 0.4 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 AJZ76293.1 - 9.1e-06 25.5 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AJZ76293.1 - 1.4e-05 24.3 0.1 0.00012 21.2 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AJZ76293.1 - 1.9e-05 24.7 1.5 0.00086 19.3 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 AJZ76293.1 - 2e-05 24.7 1.2 0.062 13.4 0.1 2.5 1 1 1 2 2 2 2 AAA domain PhoH PF02562.11 AJZ76293.1 - 0.0002 20.6 0.9 0.44 9.7 0.3 2.4 2 0 0 2 2 2 2 PhoH-like protein DUF87 PF01935.12 AJZ76293.1 - 0.00036 20.4 2.8 0.23 11.2 0.9 2.4 2 1 0 2 2 2 2 Domain of unknown function DUF87 AAA_10 PF12846.2 AJZ76293.1 - 0.001 18.5 1.4 0.081 12.3 1.0 2.5 1 1 0 1 1 1 1 AAA-like domain DEAD PF00270.24 AJZ76293.1 - 0.0011 18.5 0.2 0.049 13.1 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 AJZ76293.1 - 0.0014 18.0 0.1 0.0052 16.2 0.1 1.9 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 AJZ76293.1 - 0.0021 17.7 0.5 0.018 14.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) MobB PF03205.9 AJZ76293.1 - 0.0028 17.3 0.6 0.12 12.0 0.0 2.7 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 AJZ76293.1 - 0.0034 16.5 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AJZ76293.1 - 0.0052 16.4 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 AJZ76293.1 - 0.0056 16.7 0.1 0.054 13.5 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 AJZ76293.1 - 0.0061 16.2 0.3 0.77 9.3 0.1 2.4 1 1 1 2 2 2 1 NACHT domain AAA_17 PF13207.1 AJZ76293.1 - 0.0085 16.9 0.1 0.024 15.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AJZ76293.1 - 0.014 14.8 0.2 0.037 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AJZ76293.1 - 0.037 14.1 0.2 0.09 12.9 0.0 2.0 2 1 0 2 2 1 0 RNA helicase T2SE PF00437.15 AJZ76293.1 - 0.04 12.8 0.2 0.23 10.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF258 PF03193.11 AJZ76293.1 - 0.041 13.0 0.0 0.085 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_31 PF13614.1 AJZ76293.1 - 0.042 13.7 0.1 0.12 12.2 0.0 2.1 2 1 0 2 2 1 0 AAA domain CbiA PF01656.18 AJZ76293.1 - 0.047 13.0 1.1 0.074 12.4 0.5 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PTPlike_phytase PF14566.1 AJZ76293.1 - 0.053 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate AAA_18 PF13238.1 AJZ76293.1 - 0.056 13.7 1.4 0.17 12.1 0.2 2.4 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 AJZ76293.1 - 0.11 12.1 1.4 3.9 6.9 0.9 2.5 1 1 0 1 1 1 0 AAA domain Shikimate_dh_N PF08501.6 AJZ76293.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain Sld5 PF05916.6 AJZ76294.1 - 7.2e-06 26.2 0.9 1e-05 25.7 0.6 1.2 1 0 0 1 1 1 1 GINS complex protein GDPD PF03009.12 AJZ76294.1 - 0.064 12.7 0.1 0.084 12.3 0.1 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family CABS1 PF15367.1 AJZ76294.1 - 0.09 11.6 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 MCM PF00493.18 AJZ76295.1 - 5.7e-125 416.5 0.2 7.9e-125 416.0 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AJZ76295.1 - 2.3e-14 53.9 0.6 1.4e-13 51.4 0.2 2.4 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 AJZ76295.1 - 6e-07 29.2 0.0 1.1e-05 25.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AJZ76295.1 - 2.7e-06 26.6 0.0 0.0002 20.5 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AJZ76295.1 - 0.00099 18.7 0.0 0.0034 16.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2540 PF10802.3 AJZ76295.1 - 0.15 11.7 0.8 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) DEAD PF00270.24 AJZ76296.1 - 1.2e-30 106.1 0.1 2.4e-30 105.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.1 AJZ76296.1 - 2.1e-11 43.8 0.3 6.3e-11 42.2 0.1 2.0 1 1 0 1 1 1 1 Helix-hairpin-helix domain Helicase_C PF00271.26 AJZ76296.1 - 4.3e-11 42.5 0.0 9.2e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AJZ76296.1 - 2.6e-09 37.1 0.0 6.7e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_2 PF12826.2 AJZ76296.1 - 4.7e-07 29.6 0.1 3e-05 23.8 0.0 3.5 3 0 0 3 3 3 1 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.4 AJZ76296.1 - 6.9e-07 28.7 0.0 2.6e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Sec63 PF02889.11 AJZ76296.1 - 1.7e-05 24.1 0.0 2.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain AAA_25 PF13481.1 AJZ76296.1 - 0.00025 20.5 0.2 0.0021 17.4 0.2 2.4 2 1 0 2 2 2 1 AAA domain RNA_pol_A_CTD PF03118.10 AJZ76296.1 - 0.0051 16.2 1.5 0.22 10.9 0.0 3.4 3 0 0 3 3 3 1 Bacterial RNA polymerase, alpha chain C terminal domain IMS_HHH PF11798.3 AJZ76296.1 - 0.027 14.5 0.0 0.25 11.4 0.0 2.6 2 0 0 2 2 2 0 IMS family HHH motif T2SE PF00437.15 AJZ76296.1 - 0.045 12.6 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Glycos_transf_4 PF00953.16 AJZ76297.1 - 8.3e-29 100.4 14.9 8.3e-29 100.4 10.4 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF3989 PF13150.1 AJZ76297.1 - 0.16 11.4 1.0 2.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Reticulon PF02453.12 AJZ76297.1 - 3.7 7.1 7.4 17 5.0 0.2 2.6 1 1 1 2 2 2 0 Reticulon Hexapep PF00132.19 AJZ76298.1 - 7.5e-26 88.4 12.4 1.6e-09 36.8 0.1 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AJZ76298.1 - 1.1e-15 56.9 8.2 5.8e-07 28.9 3.3 4.9 4 1 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Trm112p PF03966.11 AJZ76299.1 - 1.7e-08 34.7 0.1 3.9e-08 33.5 0.1 1.6 1 1 0 1 1 1 1 Trm112p-like protein GFO_IDH_MocA PF01408.17 AJZ76300.1 - 2.9e-28 98.8 0.0 5.8e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AJZ76300.1 - 1.2e-07 31.4 0.0 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 AJZ76300.1 - 0.00028 21.2 0.1 0.0014 18.9 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 AJZ76300.1 - 0.00059 19.7 0.1 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 AJZ76300.1 - 0.00085 18.7 0.1 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 AJZ76300.1 - 0.0012 18.0 0.1 0.0025 17.0 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 AJZ76300.1 - 0.019 15.3 0.5 0.062 13.7 0.0 1.9 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Phytoreo_S7 PF07236.6 AJZ76300.1 - 0.024 12.9 0.1 0.033 12.5 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus S7 protein Semialdhyde_dh PF01118.19 AJZ76300.1 - 0.09 13.0 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 AJZ76300.1 - 0.097 12.0 0.6 0.54 9.6 0.4 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.7 AJZ76300.1 - 0.1 13.1 0.2 5 7.6 0.1 2.5 1 1 1 2 2 2 0 Methyltransferase domain Saccharop_dh PF03435.13 AJZ76300.1 - 0.12 11.3 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ThiF PF00899.16 AJZ76300.1 - 0.2 11.4 2.3 1.6 8.5 0.2 2.7 2 1 1 3 3 3 0 ThiF family Aminotran_4 PF01063.14 AJZ76301.1 - 1.6e-40 139.0 0.0 1.9e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV HEAT_2 PF13646.1 AJZ76303.1 - 6e-16 58.5 0.9 3e-11 43.4 0.2 2.7 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.17 AJZ76303.1 - 3.1e-10 39.2 0.0 0.043 13.9 0.0 4.4 4 0 0 4 4 4 4 HEAT repeat HEAT_EZ PF13513.1 AJZ76303.1 - 8.6e-08 32.4 1.5 0.27 11.7 0.0 4.4 5 0 0 5 5 5 2 HEAT-like repeat Arm PF00514.18 AJZ76303.1 - 0.00023 20.8 0.1 0.13 12.1 0.0 3.1 3 1 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 AJZ76303.1 - 0.012 15.9 1.1 6 7.6 0.1 3.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Alba PF01918.16 AJZ76304.1 - 4e-10 39.1 0.7 4.8e-10 38.8 0.1 1.5 2 0 0 2 2 2 1 Alba Waikav_capsid_1 PF12264.3 AJZ76304.1 - 0.051 12.8 0.1 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Waikavirus capsid protein 1 PEP_mutase PF13714.1 AJZ76305.1 - 1.1e-58 198.3 0.1 1.3e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 AJZ76305.1 - 9.2e-18 63.7 0.3 1.4e-17 63.1 0.1 1.4 2 0 0 2 2 2 1 Isocitrate lyase family DUF881 PF05949.7 AJZ76305.1 - 0.04 13.3 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) HisG_C PF08029.6 AJZ76305.1 - 0.048 13.5 0.0 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 HisG, C-terminal domain PadR PF03551.9 AJZ76308.1 - 5.4e-11 42.1 0.1 1.4e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family HTH_45 PF14947.1 AJZ76308.1 - 8.7e-06 25.4 0.5 2.1e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix Mrr_N PF14338.1 AJZ76308.1 - 0.015 15.3 0.3 0.046 13.8 0.0 1.9 2 0 0 2 2 2 0 Mrr N-terminal domain Stork_head PF10264.4 AJZ76308.1 - 0.027 14.6 0.2 0.55 10.4 0.0 2.5 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain DUF1451 PF07295.6 AJZ76308.1 - 0.035 13.8 3.3 0.4 10.4 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) IZUMO PF15005.1 AJZ76308.1 - 0.7 9.9 3.6 7.1 6.6 0.2 2.0 1 1 1 2 2 2 0 Izumo sperm-egg fusion FAD_binding_2 PF00890.19 AJZ76309.1 - 6.2e-102 341.5 0.1 7.6e-102 341.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 AJZ76309.1 - 1.3e-36 125.2 0.4 2.1e-36 124.6 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 AJZ76309.1 - 1.5e-08 34.7 1.2 0.0012 18.7 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AJZ76309.1 - 4.2e-05 22.6 0.1 0.0064 15.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 AJZ76309.1 - 0.00021 20.5 1.0 0.0036 16.4 0.7 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AJZ76309.1 - 0.00039 19.0 0.2 0.34 9.3 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 AJZ76309.1 - 0.0014 17.7 1.9 0.0092 15.1 0.2 2.7 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 AJZ76309.1 - 0.0014 17.5 0.2 0.049 12.4 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 AJZ76309.1 - 0.0083 15.0 0.2 0.017 14.0 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Sdh_cyt PF01127.17 AJZ76310.1 - 7.1e-10 38.7 2.3 9.3e-10 38.3 1.6 1.3 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sdh_cyt PF01127.17 AJZ76311.1 - 1e-08 34.9 2.0 1.3e-08 34.6 1.4 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ferric_reduct PF01794.14 AJZ76311.1 - 0.13 12.4 3.1 0.15 12.1 2.1 1.3 1 1 0 1 1 1 0 Ferric reductase like transmembrane component DUF3147 PF11345.3 AJZ76311.1 - 0.17 11.9 1.7 1.3 9.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) DUF59 PF01883.14 AJZ76312.1 - 3.4e-14 52.5 0.0 4.9e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF59 BetaGal_dom3 PF13363.1 AJZ76313.1 - 0.033 13.5 0.1 0.11 11.8 0.1 1.9 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 DUF1682 PF07946.9 AJZ76313.1 - 0.046 12.5 12.4 0.054 12.3 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDHD PF02862.12 AJZ76313.1 - 0.96 9.1 5.6 1.1 9.0 3.9 1.2 1 0 0 1 1 1 0 DDHD domain Inositol_P PF00459.20 AJZ76314.1 - 1.6e-31 109.6 0.0 1.8e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 AJZ76314.1 - 6.5e-06 25.1 0.1 1.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase CPSase_L_D2 PF02786.12 AJZ76316.1 - 1.5e-71 240.0 0.0 2.2e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 AJZ76316.1 - 1.3e-43 147.5 0.0 2.3e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AJZ76316.1 - 3.6e-33 113.7 0.0 7.7e-33 112.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 AJZ76316.1 - 2.1e-19 70.0 0.1 4.6e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AJZ76316.1 - 7.9e-14 51.1 0.0 1e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AJZ76316.1 - 2.9e-10 39.7 0.1 5.6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 AJZ76316.1 - 1.9e-08 34.0 0.0 1.8e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 AJZ76316.1 - 8.8e-08 31.7 0.1 2.4e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 AJZ76316.1 - 7.8e-06 25.8 0.0 1.6e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 AJZ76316.1 - 0.016 14.7 0.0 0.042 13.3 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_YheCD PF14398.1 AJZ76316.1 - 0.049 12.4 0.0 0.12 11.1 0.0 1.6 1 0 0 1 1 1 0 YheC/D like ATP-grasp ATP-grasp_5 PF13549.1 AJZ76316.1 - 0.086 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl PF00364.17 AJZ76317.1 - 2e-17 62.5 6.7 2.4e-17 62.3 3.7 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 AJZ76317.1 - 1.9e-12 46.6 4.0 3e-08 33.1 0.3 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD PF00529.15 AJZ76317.1 - 6.2e-07 29.0 3.4 0.0005 19.4 0.2 2.1 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 AJZ76317.1 - 1e-05 25.7 0.8 0.28 11.5 0.0 3.0 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_2 PF12700.2 AJZ76317.1 - 0.00018 20.8 6.2 0.00055 19.1 0.6 2.6 2 1 1 3 3 3 2 HlyD family secretion protein DUF2118 PF09891.4 AJZ76317.1 - 0.00028 20.6 0.8 0.0021 17.8 0.2 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.14 AJZ76317.1 - 0.0012 18.4 1.5 0.0024 17.5 0.6 1.9 2 0 0 2 2 2 1 Glycine cleavage H-protein RnfC_N PF13375.1 AJZ76317.1 - 0.031 14.0 3.7 0.078 12.7 2.3 1.8 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain QRPTase_N PF02749.11 AJZ76317.1 - 0.049 13.4 0.1 0.15 11.8 0.0 2.0 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Peptidase_M23 PF01551.17 AJZ76317.1 - 0.077 13.0 2.1 2.2 8.3 0.1 3.1 2 1 0 2 2 2 0 Peptidase family M23 PASTA PF03793.14 AJZ76317.1 - 0.11 12.0 2.7 0.16 11.6 0.5 2.1 1 1 1 2 2 2 0 PASTA domain AhpC-TSA PF00578.16 AJZ76318.1 - 3.9e-34 117.0 0.0 4.5e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AJZ76318.1 - 6.3e-24 84.1 0.0 7.1e-24 84.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin Oxidored_q4 PF00507.14 AJZ76319.1 - 8.7e-15 54.3 1.0 1.1e-14 54.1 0.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 PsbH PF00737.15 AJZ76319.1 - 0.3 10.6 4.7 0.16 11.5 0.3 2.5 2 1 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein DUF2244 PF10003.4 AJZ76319.1 - 1.7 7.9 8.8 2 7.7 2.8 2.2 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) Gram_pos_anchor PF00746.16 AJZ76319.1 - 1.9 8.3 4.1 0.96 9.3 0.3 2.2 2 0 0 2 2 2 0 Gram positive anchor Oxidored_q6 PF01058.17 AJZ76320.1 - 1.7e-24 85.8 0.1 2.3e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_30kDa PF00329.14 AJZ76321.1 - 1.7e-28 98.8 0.8 4e-28 97.6 0.1 1.9 2 1 0 2 2 2 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit AMP-binding_C_2 PF14535.1 AJZ76321.1 - 0.054 13.5 0.4 0.086 12.8 0.3 1.3 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Complex1_49kDa PF00346.14 AJZ76322.1 - 3.3e-56 190.2 0.0 7.2e-45 153.0 0.0 2.1 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NADHdh PF00146.16 AJZ76323.1 - 6.1e-80 268.5 14.4 8.8e-80 268.0 10.0 1.2 1 0 0 1 1 1 1 NADH dehydrogenase Fer4 PF00037.22 AJZ76324.1 - 2.5e-12 45.8 11.4 2.6e-09 36.2 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 AJZ76324.1 - 1.5e-09 37.5 17.2 2.3e-06 27.2 7.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 AJZ76324.1 - 2.1e-09 37.6 9.6 3.4e-09 36.9 6.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AJZ76324.1 - 8.9e-09 35.0 19.5 2.3e-06 27.3 7.0 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 AJZ76324.1 - 2.5e-08 33.3 10.8 6.9e-05 22.5 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 AJZ76324.1 - 9.9e-08 32.2 1.3 0.0019 18.4 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 AJZ76324.1 - 9.4e-07 29.4 17.0 6.9e-05 23.5 6.6 1.9 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 AJZ76324.1 - 9.6e-07 28.9 8.9 3e-06 27.4 6.5 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 AJZ76324.1 - 5.2e-06 26.0 1.8 5.2e-06 26.0 1.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_8 PF13183.1 AJZ76324.1 - 7.3e-06 25.9 18.0 0.00027 20.9 6.9 1.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 AJZ76324.1 - 1.4e-05 25.0 9.4 0.0024 18.0 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 AJZ76324.1 - 0.00014 22.3 4.7 0.087 13.4 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 AJZ76324.1 - 0.0024 18.2 11.8 0.0053 17.1 0.7 2.2 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_3 PF12798.2 AJZ76324.1 - 0.0058 17.1 4.0 0.0058 17.1 2.8 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_13 PF13370.1 AJZ76324.1 - 0.028 14.8 8.6 0.15 12.4 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain DUF2607 PF10795.4 AJZ76324.1 - 0.11 12.3 0.2 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) Oxidored_q3 PF00499.15 AJZ76325.1 - 9.2e-20 70.8 12.2 1.2e-19 70.5 8.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4040 PF13244.1 AJZ76325.1 - 0.02 14.8 10.1 0.02 14.8 7.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4040) MIG-14_Wnt-bd PF06664.7 AJZ76325.1 - 0.13 11.0 3.3 0.42 9.4 1.9 1.8 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion Oxidored_q2 PF00420.19 AJZ76326.1 - 7e-24 83.2 4.5 7.8e-24 83.1 3.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Oxidored_q1_C PF01010.14 AJZ76326.1 - 0.22 11.0 2.0 0.25 10.8 1.4 1.0 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus BphX PF06139.7 AJZ76326.1 - 0.59 9.7 4.2 2.6 7.6 2.9 1.8 1 1 0 1 1 1 0 BphX-like YiaAB PF05360.9 AJZ76326.1 - 0.68 9.5 4.7 1.8 8.1 0.2 2.3 2 0 0 2 2 2 0 yiaA/B two helix domain DUF3165 PF11364.3 AJZ76326.1 - 2.7 8.2 7.2 3.2 7.9 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3165) DUF308 PF03729.8 AJZ76326.1 - 6.4 6.8 9.4 15 5.6 1.8 2.2 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) IncA PF04156.9 AJZ76326.1 - 8.4 5.9 7.8 5.7 6.4 0.7 2.1 2 0 0 2 2 2 0 IncA protein Oxidored_q1 PF00361.15 AJZ76327.1 - 6.4e-64 215.8 21.2 6.4e-64 215.8 14.7 2.8 3 0 0 3 3 3 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 AJZ76327.1 - 0.015 14.8 0.2 0.015 14.8 0.1 2.6 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q1 PF00361.15 AJZ76328.1 - 9.9e-63 211.9 22.9 9.9e-63 211.9 15.9 2.6 2 0 0 2 2 2 1 NADH-Ubiquinone/plastoquinone (complex I), various chains polyprenyl_synt PF00348.12 AJZ76329.1 - 9.7e-43 145.8 0.0 1.4e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase TENA_THI-4 PF03070.11 AJZ76330.1 - 1.9e-11 44.1 1.2 2.6e-11 43.6 0.8 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.1 AJZ76330.1 - 5.8e-07 29.6 0.4 3.3e-06 27.2 0.1 2.0 1 1 1 2 2 2 1 Iron-containing redox enzyme HisKA PF00512.20 AJZ76331.1 - 1.1e-06 28.5 0.0 3e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain MEDS PF14417.1 AJZ76332.1 - 1.1e-15 57.1 0.3 1.3e-15 56.9 0.2 1.0 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain KaiC PF06745.8 AJZ76332.1 - 8.1e-06 25.1 0.1 1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 KaiC Usp PF00582.21 AJZ76333.1 - 1e-23 84.0 0.0 1.2e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family TBP PF00352.16 AJZ76334.1 - 1.5e-59 197.3 0.0 3e-29 100.2 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AJZ76334.1 - 1.9e-06 27.7 0.0 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pribosyltran PF00156.22 AJZ76335.1 - 4.1e-14 52.3 0.6 1e-13 51.0 0.4 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 AJZ76335.1 - 0.00061 19.1 0.1 0.0023 17.2 0.0 1.8 1 1 1 2 2 2 1 Phosphoribosyl transferase UPRTase PF14681.1 AJZ76335.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Peptidase_M50 PF02163.17 AJZ76336.1 - 4.5e-16 58.3 6.7 2.1e-14 52.8 4.7 2.5 1 1 0 1 1 1 1 Peptidase family M50 Acetyltransf_1 PF00583.19 AJZ76337.1 - 2.2e-19 69.2 0.1 3.5e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AJZ76337.1 - 3.1e-12 46.4 0.3 5.2e-12 45.7 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AJZ76337.1 - 4.7e-11 42.8 0.0 7.3e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AJZ76337.1 - 4.5e-10 39.1 0.0 2e-09 37.0 0.0 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 AJZ76337.1 - 8.3e-09 35.4 0.0 1.5e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AJZ76337.1 - 5.1e-07 29.7 0.1 7.1e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AJZ76337.1 - 0.00012 21.9 0.0 0.00035 20.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AJZ76337.1 - 0.00013 22.1 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 AJZ76337.1 - 0.00071 18.4 0.2 0.00099 18.0 0.1 1.2 1 1 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.1 AJZ76337.1 - 0.013 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Gly_acyl_tr_C PF08444.5 AJZ76337.1 - 0.062 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region GNAT_acetyltr_2 PF13718.1 AJZ76337.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF1469 PF07332.6 AJZ76338.1 - 0.043 13.5 0.2 0.055 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Zip PF02535.17 AJZ76338.1 - 0.19 10.6 3.3 0.22 10.4 2.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BPD_transp_1 PF00528.17 AJZ76338.1 - 0.39 10.2 4.1 0.4 10.1 2.8 1.0 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF1049 PF06305.6 AJZ76338.1 - 3.4 7.1 6.0 1.2 8.6 2.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) ABC_tran PF00005.22 AJZ76339.1 - 1e-38 132.7 0.3 9.4e-18 64.8 0.0 3.0 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 AJZ76339.1 - 2.5e-11 42.9 3.0 2.5e-11 42.9 2.1 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 AJZ76339.1 - 3e-10 40.5 5.7 0.007 16.3 0.0 4.6 3 2 0 3 3 3 2 AAA domain Fer4 PF00037.22 AJZ76339.1 - 4.3e-09 35.5 11.5 1.1e-08 34.2 4.0 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.2 AJZ76339.1 - 2e-08 33.7 16.1 6.2e-08 32.1 3.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain SMC_N PF02463.14 AJZ76339.1 - 1.1e-07 31.3 5.2 0.00087 18.5 0.4 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Fer4_2 PF12797.2 AJZ76339.1 - 2.7e-06 26.9 12.3 7.8e-06 25.5 2.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 AJZ76339.1 - 4.5e-06 26.9 10.8 9.5e-06 25.9 7.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AJZ76339.1 - 7.4e-05 22.5 13.0 0.00013 21.7 9.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_29 PF13555.1 AJZ76339.1 - 0.00013 21.4 0.2 0.075 12.5 0.0 3.2 4 0 0 4 4 3 1 P-loop containing region of AAA domain Fer4_10 PF13237.1 AJZ76339.1 - 0.00022 20.9 2.0 0.00022 20.9 1.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_15 PF13175.1 AJZ76339.1 - 0.00086 18.4 0.7 2 7.3 0.0 3.1 2 1 0 3 3 3 2 AAA ATPase domain Fer4_9 PF13187.1 AJZ76339.1 - 0.0014 18.8 11.7 0.0031 17.7 8.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain DUF258 PF03193.11 AJZ76339.1 - 0.0023 17.1 0.1 0.11 11.6 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function, DUF258 Miro PF08477.8 AJZ76339.1 - 0.0056 17.1 0.2 2.4 8.6 0.1 2.9 2 1 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 AJZ76339.1 - 0.0065 15.8 0.0 2.2 7.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain Fer4_3 PF12798.2 AJZ76339.1 - 0.0066 16.9 5.4 0.0066 16.9 3.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain SbcCD_C PF13558.1 AJZ76339.1 - 0.008 16.0 0.0 3.2 7.7 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_4 PF12800.2 AJZ76339.1 - 0.012 15.9 3.1 0.012 15.9 2.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.1 AJZ76339.1 - 0.016 15.7 1.4 0.016 15.7 1.0 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain NB-ARC PF00931.17 AJZ76339.1 - 0.028 13.2 1.3 3.5 6.3 0.1 2.9 3 1 0 3 3 3 0 NB-ARC domain AAA_16 PF13191.1 AJZ76339.1 - 0.04 13.8 1.0 0.22 11.4 0.1 2.6 3 1 0 3 3 3 0 AAA ATPase domain Fer4_16 PF13484.1 AJZ76339.1 - 0.042 14.6 12.7 0.44 11.3 8.9 2.3 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain RNA_helicase PF00910.17 AJZ76339.1 - 0.047 13.8 0.1 9 6.5 0.0 3.7 4 0 0 4 4 4 0 RNA helicase VirE PF05272.6 AJZ76339.1 - 0.095 12.1 0.1 0.63 9.4 0.0 2.3 3 0 0 3 3 2 0 Virulence-associated protein E Fer4_8 PF13183.1 AJZ76339.1 - 0.12 12.4 7.1 0.55 10.2 5.4 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_14 PF13173.1 AJZ76339.1 - 0.12 12.3 1.4 4.4 7.2 0.0 3.7 4 1 1 5 5 4 0 AAA domain Fer4_17 PF13534.1 AJZ76339.1 - 0.87 9.9 8.6 0.17 12.2 0.7 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.1 AJZ76339.1 - 7.3 7.0 11.1 0.56 10.6 2.9 2.3 1 1 0 2 2 2 0 4Fe-4S dicluster domain Peptidase_M17 PF00883.16 AJZ76340.1 - 1.9e-113 378.4 0.0 2.7e-113 377.9 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 AJZ76340.1 - 6.3e-16 58.2 0.2 1.6e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DUF393 PF04134.7 AJZ76341.1 - 0.0074 17.3 0.0 0.01 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Transaldolase PF00923.14 AJZ76342.1 - 7.1e-62 209.1 0.1 1.1e-60 205.2 0.1 2.2 1 1 0 1 1 1 1 Transaldolase FMN_dh PF01070.13 AJZ76342.1 - 0.069 11.9 0.1 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF2884 PF11101.3 AJZ76343.1 - 0.16 11.3 0.5 0.2 11.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) TBP PF00352.16 AJZ76344.1 - 7.4e-60 198.3 0.0 1.5e-29 101.1 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AJZ76344.1 - 2.4e-06 27.5 0.0 0.0062 16.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Phage_Gp111 PF07410.6 AJZ76344.1 - 0.097 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein ASCH PF04266.9 AJZ76345.1 - 2.6e-10 40.6 0.0 3.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 ASCH domain VWA PF00092.23 AJZ76346.1 - 2.9e-12 46.6 0.1 4e-11 42.9 0.1 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 AJZ76346.1 - 1.7e-10 41.2 0.0 5.1e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.1 AJZ76346.1 - 2.4e-06 27.3 0.0 4.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 AJZ76346.1 - 2.8e-05 24.0 0.6 0.00047 20.0 0.0 2.6 2 1 0 2 2 2 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 AJZ76346.1 - 0.0026 16.9 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2201 PF09967.4 AJZ76346.1 - 0.0055 16.7 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 VWA-like domain (DUF2201) AAA_5 PF07728.9 AJZ76347.1 - 5.5e-23 81.2 0.0 7.7e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AJZ76347.1 - 1.4e-11 44.1 0.0 2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 AJZ76347.1 - 9.5e-07 29.0 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AJZ76347.1 - 6.9e-06 26.1 0.2 1.8e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 AJZ76347.1 - 1.9e-05 24.5 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AJZ76347.1 - 4.5e-05 24.2 0.1 0.00014 22.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 AJZ76347.1 - 0.0003 20.5 0.1 0.00054 19.7 0.0 1.6 2 1 0 2 2 1 1 Archaeal ATPase AAA_22 PF13401.1 AJZ76347.1 - 0.00038 20.6 0.1 0.00076 19.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AJZ76347.1 - 0.00045 19.3 0.1 0.0056 15.7 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 AJZ76347.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain Miro PF08477.8 AJZ76347.1 - 0.0027 18.2 0.0 0.0069 16.8 0.0 1.7 2 0 0 2 2 1 1 Miro-like protein AAA_28 PF13521.1 AJZ76347.1 - 0.0049 16.8 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AJZ76347.1 - 0.0084 15.2 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AJZ76347.1 - 0.0095 16.2 0.3 0.017 15.4 0.2 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 AJZ76347.1 - 0.011 15.4 0.1 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 AJZ76347.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 AJZ76347.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 AJZ76347.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 AJZ76347.1 - 0.032 13.8 0.1 0.066 12.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain CbbQ_C PF08406.5 AJZ76347.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal NACHT PF05729.7 AJZ76347.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 AJZ76347.1 - 0.087 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 AJZ76347.1 - 0.14 11.5 0.3 0.28 10.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AJZ76347.1 - 0.14 12.4 0.1 0.32 11.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 AJZ76347.1 - 0.14 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_binding PF01877.12 AJZ76348.1 - 7.5e-25 87.2 0.2 8.7e-25 87.0 0.1 1.1 1 0 0 1 1 1 1 RNA binding P16-Arc PF04699.9 AJZ76348.1 - 0.035 14.1 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Ribosomal_S3Ae PF01015.13 AJZ76349.1 - 3.7e-63 212.3 5.1 4.5e-63 212.1 3.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Band_7 PF01145.20 AJZ76349.1 - 0.01 15.7 0.4 1.1 9.1 0.1 2.2 1 1 1 2 2 2 0 SPFH domain / Band 7 family tRNA-synt_2b PF00587.20 AJZ76350.1 - 8.6e-37 126.3 0.0 1.5e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 AJZ76350.1 - 1.5e-24 86.0 9.6 3.4e-24 84.9 6.6 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 AJZ76350.1 - 0.0085 15.1 7.7 0.087 11.8 1.3 3.2 4 0 0 4 4 4 2 Autophagy protein Apg6 FimP PF09766.4 AJZ76350.1 - 0.014 14.4 2.0 0.014 14.4 1.4 1.9 2 0 0 2 2 2 0 Fms-interacting protein Pcc1 PF09341.5 AJZ76351.1 - 1.7e-06 27.9 0.0 2e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DHHA1 PF02272.14 AJZ76352.1 - 1.6e-08 34.1 0.2 1.6e-08 34.1 0.1 2.2 2 0 0 2 2 2 1 DHHA1 domain DHH PF01368.15 AJZ76352.1 - 1.7e-08 34.2 0.1 3.1e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 DHH family Ank PF00023.25 AJZ76352.1 - 0.023 14.4 0.1 7.9 6.4 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat Ribosomal_S13_N PF08069.7 AJZ76353.1 - 1.7e-24 85.4 0.4 3.1e-24 84.5 0.3 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 AJZ76353.1 - 7.7e-17 60.8 1.8 1.1e-16 60.3 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 SRI PF08236.6 AJZ76353.1 - 0.029 14.3 2.1 3.3 7.7 1.4 2.1 1 1 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain ATP-cone PF03477.11 AJZ76353.1 - 0.14 12.6 0.9 0.44 11.0 0.3 1.9 1 1 1 2 2 2 0 ATP cone domain DUF4366 PF14283.1 AJZ76354.1 - 0.12 11.8 4.7 0.04 13.3 0.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) FixQ PF05545.6 AJZ76355.1 - 0.016 14.8 1.2 0.016 14.8 0.9 1.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Monooxygenase_B PF04744.7 AJZ76357.1 - 2.3e-08 33.1 0.0 7.2e-08 31.5 0.0 1.8 1 1 0 1 1 1 1 Monooxygenase subunit B protein AmoC PF04896.7 AJZ76358.1 - 2.9e-15 55.9 4.7 3.7e-15 55.6 3.3 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C ETRAMP PF09716.5 AJZ76359.1 - 0.69 9.8 0.1 0.69 9.8 0.1 2.1 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Archaeal_AmoA PF12942.2 AJZ76360.1 - 2.1e-107 356.8 9.8 2.5e-107 356.5 6.8 1.0 1 0 0 1 1 1 1 Archaeal ammonia monooxygenase subunit A (AmoA) MethyltransfD12 PF02086.10 AJZ76361.1 - 7.9e-62 209.0 0.3 9e-62 208.8 0.2 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_26 PF13659.1 AJZ76361.1 - 0.00027 20.9 0.0 0.00045 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF2089 PF09862.4 AJZ76361.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) DNA_photolyase PF00875.13 AJZ76361.1 - 0.016 14.9 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 DNA photolyase Cons_hypoth95 PF03602.10 AJZ76361.1 - 0.037 13.4 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 LOH1CR12 PF10158.4 AJZ76362.1 - 0.018 14.7 0.2 0.093 12.5 0.1 1.9 1 1 1 2 2 2 0 Tumour suppressor protein zf-Mss51 PF13824.1 AJZ76362.1 - 0.023 14.5 0.1 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 UPF0104 PF03706.8 AJZ76363.1 - 5.3e-05 22.6 0.2 0.0016 17.7 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0104) DUF3169 PF11368.3 AJZ76363.1 - 0.00061 19.0 0.1 0.00078 18.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) DUF3816 PF12822.2 AJZ76363.1 - 0.025 14.4 0.8 0.036 13.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) Cytadhesin_P30 PF07271.6 AJZ76363.1 - 0.045 13.0 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF1469 PF07332.6 AJZ76363.1 - 0.058 13.1 0.1 10 5.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) P12 PF12669.2 AJZ76363.1 - 0.29 11.3 2.0 23 5.3 0.0 3.2 3 0 0 3 3 3 0 Virus attachment protein p12 family DUF1049 PF06305.6 AJZ76363.1 - 3.1 7.3 0.0 3.1 7.3 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1049) HTH_24 PF13412.1 AJZ76364.1 - 2.9e-06 26.5 0.1 5.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 AJZ76364.1 - 6.1e-05 22.5 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.7 AJZ76364.1 - 0.0001 21.8 0.0 0.00027 20.5 0.0 1.7 1 0 0 1 1 1 1 HTH domain FaeA PF04703.7 AJZ76364.1 - 0.0011 19.0 0.1 0.0036 17.4 0.0 1.8 2 0 0 2 2 2 1 FaeA-like protein HTH_23 PF13384.1 AJZ76364.1 - 0.0017 17.9 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 AJZ76364.1 - 0.0058 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain B12-binding_2 PF02607.12 AJZ76364.1 - 0.006 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain HTH_Crp_2 PF13545.1 AJZ76364.1 - 0.0064 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_29 PF13551.1 AJZ76364.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix KorB PF08535.5 AJZ76364.1 - 0.098 12.8 0.1 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 KorB domain MarR_2 PF12802.2 AJZ76364.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.2 AJZ76364.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HrcA_DNA-bdg PF03444.10 AJZ76364.1 - 0.14 11.5 0.7 0.39 10.1 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding AhpC-TSA PF00578.16 AJZ76365.1 - 2.4e-22 78.9 0.2 3e-22 78.5 0.2 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AJZ76365.1 - 1.9e-17 63.2 0.3 2.4e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 AJZ76365.1 - 7.9e-07 29.1 0.2 1.3e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 AJZ76365.1 - 2.3e-06 27.7 0.1 3.4e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 AJZ76365.1 - 0.0042 16.7 0.5 0.15 11.7 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin DUF2393 PF09624.5 AJZ76366.1 - 0.0002 20.9 0.4 0.29 10.6 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2393) CARDB PF07705.6 AJZ76366.1 - 0.00045 20.2 0.1 0.0099 15.9 0.0 2.7 2 1 0 2 2 2 1 CARDB Wzt_C PF14524.1 AJZ76366.1 - 0.046 13.4 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 Wzt C-terminal domain DUF11 PF01345.13 AJZ76366.1 - 0.068 13.2 0.0 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF11 CTP_transf_2 PF01467.21 AJZ76367.1 - 5.9e-14 52.4 0.0 1.6e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 AJZ76367.1 - 0.11 12.1 0.3 0.32 10.6 0.1 1.8 2 0 0 2 2 2 0 FAD synthetase McrBC PF10117.4 AJZ76369.1 - 0.04 12.8 0.8 0.042 12.7 0.6 1.0 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component tRNA-synt_1b PF00579.20 AJZ76370.1 - 1.3e-28 100.0 0.0 2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.13 AJZ76370.1 - 0.019 13.6 0.0 0.095 11.3 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) B5 PF03484.10 AJZ76371.1 - 1.8e-17 62.9 0.0 3.9e-13 49.0 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetase B5 domain B3_4 PF03483.12 AJZ76371.1 - 4.1e-13 49.1 0.1 7.3e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain tRNA-synt_2d PF01409.15 AJZ76371.1 - 0.082 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) EVE PF01878.13 AJZ76372.1 - 3.2e-41 140.6 1.7 3.7e-41 140.5 1.2 1.0 1 0 0 1 1 1 1 EVE domain Tup_N PF08581.5 AJZ76373.1 - 0.12 12.5 1.7 0.48 10.6 0.1 2.1 2 0 0 2 2 2 0 Tup N-terminal C1_1 PF00130.17 AJZ76374.1 - 0.1 12.3 6.8 0.18 11.5 4.7 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Mu-like_Com PF10122.4 AJZ76374.1 - 1.4 8.0 8.3 7.2 5.7 5.8 2.0 1 1 0 1 1 1 0 Mu-like prophage protein Com Prok-RING_1 PF14446.1 AJZ76374.1 - 2.8 7.7 7.9 0.2 11.3 1.9 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Cas_Cmr5 PF09701.5 AJZ76375.1 - 0.054 13.6 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) Aconitase PF00330.15 AJZ76376.1 - 2.3e-153 511.0 0.1 2.5e-152 507.6 0.1 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AJZ76376.1 - 5.2e-39 133.3 0.0 1.4e-38 131.9 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF521 PF04412.8 AJZ76376.1 - 0.017 13.6 0.0 0.03 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Holin_BlyA PF05102.7 AJZ76377.1 - 0.019 14.6 4.3 0.045 13.4 0.0 3.2 2 0 0 2 2 2 0 holin, BlyA family DUF3366 PF11846.3 AJZ76377.1 - 0.019 14.8 1.1 0.54 10.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) Glycophorin_A PF01102.13 AJZ76377.1 - 9.4 6.0 11.6 4.6 7.0 1.4 3.5 3 0 0 3 3 3 0 Glycophorin A SOR_SNZ PF01680.12 AJZ76378.1 - 1e-90 302.9 3.6 1e-90 302.9 2.5 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 AJZ76378.1 - 1.6e-07 30.6 1.4 4.9e-06 25.7 0.1 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 AJZ76378.1 - 9e-06 25.1 0.6 0.0052 16.0 0.0 3.1 2 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 AJZ76378.1 - 3e-05 23.3 5.3 0.002 17.3 0.1 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase IGPS PF00218.16 AJZ76378.1 - 0.00043 19.4 0.0 0.0029 16.6 0.0 2.2 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase Dus PF01207.12 AJZ76378.1 - 0.0032 16.3 0.5 1.4 7.6 0.0 2.3 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) PcrB PF01884.12 AJZ76378.1 - 0.0037 16.5 0.2 0.18 11.0 0.0 2.6 1 1 2 3 3 3 1 PcrB family NanE PF04131.9 AJZ76378.1 - 0.0045 15.9 2.2 0.12 11.3 0.0 2.8 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.19 AJZ76378.1 - 0.016 14.6 0.6 3.3 7.0 0.0 2.6 2 1 1 3 3 3 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Phos_pyr_kin PF08543.7 AJZ76378.1 - 0.038 13.1 0.6 0.063 12.4 0.4 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase SNO PF01174.14 AJZ76379.1 - 7.4e-50 169.1 0.0 8.4e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 AJZ76379.1 - 3.2e-13 49.5 0.0 5.1e-13 48.9 0.0 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 AJZ76379.1 - 3e-12 46.4 0.0 6.4e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 AJZ76379.1 - 1e-05 25.3 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.19 AJZ76379.1 - 1.8e-05 24.2 0.1 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.8 AJZ76379.1 - 3.4e-05 23.3 0.4 0.0019 17.7 0.3 2.9 1 1 0 1 1 1 1 Peptidase C26 DUF4066 PF13278.1 AJZ76379.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase tRNA-synt_1 PF00133.17 AJZ76380.1 - 4.6e-111 371.7 0.1 3.1e-110 368.9 0.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AJZ76380.1 - 7e-30 103.8 1.3 1.6e-29 102.6 0.9 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AJZ76380.1 - 1.7e-24 86.2 2.7 9.3e-14 50.8 0.0 3.5 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 AJZ76380.1 - 0.00015 21.0 0.3 0.025 13.8 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 UBN2_2 PF14227.1 AJZ76380.1 - 0.037 13.5 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF3633 PF12315.3 AJZ76380.1 - 0.038 13.2 0.0 0.093 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) Pterin_4a PF01329.14 AJZ76381.1 - 2.1e-34 117.1 0.2 2.2e-34 117.0 0.2 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.3 AJZ76381.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Translation-initiation factor 2 Asn_synthase PF00733.16 AJZ76382.1 - 3.2e-33 115.3 0.0 7.3e-33 114.1 0.0 1.5 1 1 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 AJZ76382.1 - 6.2e-07 28.5 0.1 1.4e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 NAD synthase QueC PF06508.8 AJZ76382.1 - 8.7e-05 21.8 0.1 0.00019 20.7 0.1 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 AJZ76382.1 - 0.00017 20.2 0.1 0.0021 16.6 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.15 AJZ76382.1 - 0.00072 19.0 0.4 0.0072 15.8 0.3 2.3 1 1 0 1 1 1 1 PP-loop family ATP_bind_4 PF01902.12 AJZ76382.1 - 0.021 14.1 0.0 0.46 9.8 0.0 2.4 2 1 0 2 2 2 0 ATP-binding region Peptidase_M20 PF01546.23 AJZ76382.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 Lyase_1 PF00206.15 AJZ76383.1 - 1.5e-46 159.0 0.5 2.3e-46 158.4 0.3 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 AJZ76383.1 - 5.6e-20 71.1 0.0 1.4e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus RtcB PF01139.12 AJZ76384.1 - 7.1e-154 512.8 0.0 8e-154 512.6 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB DUF3492 PF11997.3 AJZ76384.1 - 0.0048 16.4 0.1 0.0078 15.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Complex1_LYR PF05347.10 AJZ76384.1 - 0.12 12.1 0.3 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Complex 1 protein (LYR family) dsDNA_bind PF01984.15 AJZ76385.1 - 6.1e-07 29.3 0.9 7.8e-07 29.0 0.6 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.4 AJZ76385.1 - 0.004 17.2 3.6 0.01 15.9 2.5 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region Orthopox_F8 PF05886.6 AJZ76385.1 - 0.0049 16.6 0.1 0.007 16.1 0.1 1.3 1 0 0 1 1 1 1 Orthopoxvirus F8 protein DUF2370 PF10176.4 AJZ76385.1 - 0.1 11.8 0.1 0.18 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) TMEM51 PF15345.1 AJZ76385.1 - 0.15 11.7 0.9 0.17 11.5 0.5 1.2 1 1 0 1 1 1 0 Transmembrane protein 51 Ribosomal_S11 PF00411.14 AJZ76387.1 - 1.8e-38 131.0 0.9 2.1e-38 130.8 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Tagatose_6_P_K PF08013.6 AJZ76387.1 - 0.028 12.8 0.0 0.035 12.5 0.0 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase AIRS PF00586.19 AJZ76388.1 - 4.7e-11 42.7 0.0 9.8e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.17 AJZ76388.1 - 0.0008 19.4 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.10 AJZ76388.1 - 0.047 14.1 0.6 2.5 8.6 0.1 3.0 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain DUF2683 PF10884.3 AJZ76388.1 - 0.16 11.9 0.2 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) PGM_PMM_I PF02878.11 AJZ76389.1 - 6.6e-25 87.1 0.0 4.1e-24 84.6 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 AJZ76389.1 - 4.3e-17 62.1 0.1 1.1e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 AJZ76389.1 - 8.5e-13 48.5 0.1 2.3e-12 47.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 AJZ76389.1 - 5.5e-08 32.6 0.1 2.1e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain B12-binding PF02310.14 AJZ76389.1 - 0.053 13.3 0.1 0.43 10.4 0.0 2.3 2 1 0 2 2 2 0 B12 binding domain KH_1 PF00013.24 AJZ76389.1 - 0.067 12.8 0.4 0.83 9.3 0.2 2.6 3 0 0 3 3 3 0 KH domain HTH_45 PF14947.1 AJZ76390.1 - 2.5e-16 59.2 0.2 2.8e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_34 PF13601.1 AJZ76390.1 - 0.0012 18.8 0.1 0.0014 18.5 0.1 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain Mrr_N PF14338.1 AJZ76390.1 - 0.0024 17.9 0.0 0.0027 17.7 0.0 1.1 1 0 0 1 1 1 1 Mrr N-terminal domain DUF4364 PF14277.1 AJZ76390.1 - 0.0037 16.9 0.1 0.0046 16.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) RPA_C PF08784.6 AJZ76390.1 - 0.026 14.9 0.1 0.033 14.6 0.0 1.2 1 0 0 1 1 1 0 Replication protein A C terminal Rrf2 PF02082.15 AJZ76390.1 - 0.033 14.2 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.14 AJZ76390.1 - 0.049 13.3 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2092 PF09865.4 AJZ76390.1 - 0.073 12.1 0.0 0.079 12.0 0.0 1.0 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) DUF505 PF04458.7 AJZ76390.1 - 0.093 10.8 0.0 0.097 10.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF505) AIPR PF10592.4 AJZ76392.1 - 5.3e-64 216.4 5.2 5.3e-64 216.4 3.6 2.0 2 1 0 2 2 2 1 AIPR protein RGS PF00615.14 AJZ76392.1 - 0.019 15.0 0.5 0.09 12.8 0.0 2.4 2 0 0 2 2 2 0 Regulator of G protein signaling domain Cupredoxin_1 PF13473.1 AJZ76393.1 - 1e-07 31.7 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.15 AJZ76393.1 - 8.9e-06 25.8 0.1 2.6e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family CBFD_NFYB_HMF PF00808.18 AJZ76394.1 - 4.1e-13 49.1 0.1 4.4e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AJZ76394.1 - 5.5e-08 32.8 0.1 6.4e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AJZ76394.1 - 6.5e-05 23.0 0.0 7.6e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TFIID-31kDa PF02291.10 AJZ76394.1 - 0.00071 19.3 0.0 0.00077 19.2 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 AJZ76394.1 - 0.0009 18.9 0.0 0.00096 18.8 0.0 1.1 1 0 0 1 1 1 1 Bromodomain associated TAF PF02969.12 AJZ76394.1 - 0.066 13.1 0.4 0.076 12.9 0.3 1.1 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Ribosomal_S17e PF00833.13 AJZ76395.1 - 8.7e-19 67.4 3.7 9.3e-19 67.3 2.5 1.0 1 0 0 1 1 1 1 Ribosomal S17 DUF2334 PF10096.4 AJZ76395.1 - 0.085 12.2 0.1 0.095 12.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_transf_41 PF13844.1 AJZ76395.1 - 0.26 9.2 1.9 0.29 9.0 1.3 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 41 DUF3134 PF11332.3 AJZ76395.1 - 0.53 10.4 4.9 0.97 9.6 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) ThiS PF02597.15 AJZ76396.1 - 9.6e-11 41.9 0.0 1.7e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 ThiS family CGI-121 PF08617.5 AJZ76396.1 - 9.2e-08 31.9 2.0 1.4e-07 31.3 1.4 1.3 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Urm1 PF09138.6 AJZ76396.1 - 0.0073 16.4 0.2 0.023 14.8 0.1 1.9 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) THUMP PF02926.12 AJZ76397.1 - 9.6e-11 41.7 0.1 1.2e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 THUMP domain HTH_45 PF14947.1 AJZ76398.1 - 2.2e-12 46.6 0.1 3e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.2 AJZ76398.1 - 3.4e-05 23.4 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 AJZ76398.1 - 0.00078 19.7 0.0 0.00099 19.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain Mrr_N PF14338.1 AJZ76398.1 - 0.0028 17.7 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Mrr N-terminal domain RPA_C PF08784.6 AJZ76398.1 - 0.0033 17.8 0.0 0.0044 17.4 0.0 1.2 1 0 0 1 1 1 1 Replication protein A C terminal TrmB PF01978.14 AJZ76398.1 - 0.0081 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 AJZ76398.1 - 0.0088 15.6 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain DUF4364 PF14277.1 AJZ76398.1 - 0.016 14.8 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) FeoC PF09012.5 AJZ76398.1 - 0.017 14.8 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_34 PF13601.1 AJZ76398.1 - 0.022 14.7 0.1 0.041 13.9 0.0 1.4 1 1 0 1 1 1 0 Winged helix DNA-binding domain HTH_24 PF13412.1 AJZ76398.1 - 0.023 14.0 0.1 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PadR PF03551.9 AJZ76398.1 - 0.024 14.4 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Rrf2 PF02082.15 AJZ76398.1 - 0.035 14.2 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator MarR PF01047.17 AJZ76398.1 - 0.038 13.6 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 MarR family RNA_pol_Rpc34 PF05158.7 AJZ76398.1 - 0.09 11.9 0.0 0.098 11.8 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit DUF4194 PF13835.1 AJZ76398.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) RQC PF09382.5 AJZ76398.1 - 0.11 12.1 0.1 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 RQC domain MerC PF03203.9 AJZ76399.1 - 0.14 12.5 10.3 1.5 9.2 1.2 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein PIRT PF15099.1 AJZ76399.1 - 8.6 5.5 11.3 2.5 7.3 0.2 3.0 2 2 2 4 4 4 0 Phosphoinositide-interacting protein family Lar_restr_allev PF14354.1 AJZ76400.1 - 0.013 15.7 1.5 0.059 13.6 1.0 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar Ribosomal_S27e PF01667.12 AJZ76400.1 - 0.02 14.3 2.9 2.5 7.6 0.3 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 zinc-ribbons_6 PF07191.7 AJZ76400.1 - 0.028 14.1 0.5 0.037 13.8 0.3 1.2 1 0 0 1 1 1 0 zinc-ribbons IBR PF01485.16 AJZ76400.1 - 0.052 13.4 0.9 0.074 12.9 0.6 1.2 1 0 0 1 1 1 0 IBR domain Stc1 PF12898.2 AJZ76400.1 - 0.055 13.5 0.2 0.064 13.3 0.1 1.1 1 0 0 1 1 1 0 Stc1 domain zinc_ribbon_4 PF13717.1 AJZ76400.1 - 0.071 12.8 4.5 0.51 10.0 3.1 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AJZ76400.1 - 0.076 12.6 4.3 0.51 9.9 3.0 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zf-TFIIB PF13453.1 AJZ76400.1 - 0.16 11.1 3.3 0.16 11.2 1.1 1.9 2 1 0 2 2 2 0 Transcription factor zinc-finger DUF329 PF03884.9 AJZ76400.1 - 0.39 10.3 2.6 1.2 8.7 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF329) zf-C2H2_3 PF13878.1 AJZ76400.1 - 0.41 10.2 2.7 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zinc_ribbon_6 PF14599.1 AJZ76400.1 - 1.9 8.3 4.3 1.6 8.5 0.2 1.9 1 1 1 2 2 2 0 Zinc-ribbon PhnA_Zn_Ribbon PF08274.7 AJZ76400.1 - 2.7 7.8 7.3 1.5 8.6 2.1 2.2 1 1 1 2 2 2 0 PhnA Zinc-Ribbon Iron_traffic PF04362.9 AJZ76401.1 - 9.4e-08 31.3 0.7 1.3e-07 30.9 0.5 1.4 1 1 0 1 1 1 1 Bacterial Fe(2+) trafficking OMPdecase PF00215.19 AJZ76404.1 - 3.1e-26 92.1 0.0 4e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family NUDIX PF00293.23 AJZ76405.1 - 2e-16 59.8 0.0 2.3e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Prenyltransf PF01255.14 AJZ76406.1 - 7.6e-78 260.6 0.2 9.2e-78 260.4 0.1 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase SpoVR PF04293.8 AJZ76406.1 - 0.084 11.2 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 SpoVR like protein DUF373 PF04123.8 AJZ76407.1 - 2.7e-103 345.6 7.6 3.4e-103 345.3 5.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF373) SPC12 PF06645.8 AJZ76407.1 - 0.85 9.4 3.0 0.58 10.0 0.1 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF4229 PF14012.1 AJZ76407.1 - 1.1 9.1 9.5 5.1 7.0 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) dTMP_synthase PF02593.9 AJZ76408.1 - 0.0021 17.4 0.9 0.003 16.9 0.6 1.4 1 1 0 1 1 1 1 Thymidylate synthase MAT1 PF06391.8 AJZ76408.1 - 0.053 13.1 0.2 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF424 PF04242.8 AJZ76409.1 - 1.7e-19 69.6 0.4 1.9e-19 69.4 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF424) DUF3972 PF13118.1 AJZ76409.1 - 0.059 13.4 0.2 0.071 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) eIF-1a PF01176.14 AJZ76410.1 - 9e-21 73.0 0.7 1.1e-20 72.7 0.5 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 KH_1 PF00013.24 AJZ76411.1 - 3.5e-12 45.7 13.9 2.2e-07 30.4 1.0 2.6 3 0 0 3 3 3 2 KH domain KH_3 PF13014.1 AJZ76411.1 - 0.00011 21.7 6.9 0.0011 18.5 0.1 2.7 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 AJZ76411.1 - 6.8 6.3 7.4 19 4.8 0.7 2.7 2 1 0 2 2 2 0 KH domain Topo-VIb_trans PF09239.6 AJZ76412.1 - 1.3e-58 197.0 0.0 2.2e-58 196.3 0.0 1.4 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c_3 PF13589.1 AJZ76412.1 - 4.3e-08 32.9 0.0 8.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AJZ76412.1 - 7.2e-08 32.1 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FbpA PF05833.6 AJZ76412.1 - 0.016 13.7 0.4 0.095 11.2 0.0 2.2 3 0 0 3 3 3 0 Fibronectin-binding protein A N-terminus (FbpA) TP6A_N PF04406.9 AJZ76413.1 - 1.7e-19 69.1 0.1 3.3e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Toprim PF01751.17 AJZ76413.1 - 0.031 14.2 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Toprim domain CheB_methylest PF01339.12 AJZ76413.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 CheB methylesterase GvpH PF05455.6 AJZ76414.1 - 0.0003 20.4 0.0 0.00036 20.2 0.0 1.1 1 0 0 1 1 1 1 GvpH DUF2207 PF09972.4 AJZ76414.1 - 0.073 11.6 2.4 0.084 11.4 1.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3043 PF11241.3 AJZ76414.1 - 0.084 12.4 0.4 0.12 11.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Tic20 PF09685.5 AJZ76414.1 - 0.11 12.5 2.4 0.16 11.9 1.7 1.2 1 0 0 1 1 1 0 Tic20-like protein DUF788 PF05620.6 AJZ76414.1 - 0.12 12.2 0.7 0.15 11.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF788) ABC2_membrane_4 PF12730.2 AJZ76415.1 - 0.001 18.2 4.1 0.0011 18.1 2.8 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF2061 PF09834.4 AJZ76415.1 - 0.0046 17.1 1.6 0.0068 16.5 1.1 1.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2061) TrmB PF01978.14 AJZ76416.1 - 0.001 18.7 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PNP_UDP_1 PF01048.15 AJZ76417.1 - 5.2e-48 163.0 0.0 6.4e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Pribosyltran PF00156.22 AJZ76418.1 - 4.9e-18 65.0 0.1 6e-18 64.7 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AJZ76418.1 - 0.0002 20.6 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase A2M_N PF01835.14 AJZ76419.1 - 7.5e-27 93.4 5.3 1.8e-06 28.1 0.0 6.1 6 1 0 6 6 6 4 MG2 domain FlgD_ig PF13860.1 AJZ76419.1 - 0.00013 21.6 16.7 0.0089 15.7 0.1 6.4 6 1 2 8 8 8 2 FlgD Ig-like domain AAA_15 PF13175.1 AJZ76420.1 - 1.2e-20 73.9 0.2 1.2e-12 47.5 0.0 3.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_21 PF13304.1 AJZ76420.1 - 5.5e-13 49.5 7.8 5.5e-13 49.5 5.4 3.6 2 2 1 3 3 3 1 AAA domain ABC_tran PF00005.22 AJZ76420.1 - 1.2e-05 25.6 0.2 7.3e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.1 AJZ76420.1 - 0.0011 19.3 5.5 0.0011 19.3 3.8 2.9 2 1 0 2 2 2 1 AAA domain DUF2813 PF11398.3 AJZ76420.1 - 0.0033 16.5 0.8 0.47 9.4 0.0 2.8 4 0 0 4 4 4 2 Protein of unknown function (DUF2813) AAA_29 PF13555.1 AJZ76420.1 - 0.0056 16.1 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 AJZ76420.1 - 0.037 13.9 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.14 AJZ76420.1 - 0.068 12.3 0.0 1.7 7.7 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Big_3_2 PF12245.3 AJZ76421.1 - 0.015 14.8 0.3 0.085 12.4 0.0 2.2 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 3) DUF296 PF03479.10 AJZ76421.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF296) FtsJ PF01728.14 AJZ76422.1 - 2.2e-48 164.6 0.0 2.5e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 AJZ76422.1 - 0.0037 16.8 0.1 0.0087 15.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJZ76422.1 - 0.0039 16.9 0.0 0.0096 15.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJZ76422.1 - 0.022 15.3 0.1 0.046 14.2 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 AJZ76422.1 - 0.15 12.4 0.1 0.36 11.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain TRM PF02005.11 AJZ76423.1 - 2.7e-74 250.3 0.0 3.1e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 AJZ76423.1 - 0.00041 19.9 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 AJZ76423.1 - 0.0021 17.4 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 AJZ76423.1 - 0.014 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RNase_HII PF01351.13 AJZ76424.1 - 3.6e-48 163.8 1.8 4.1e-48 163.6 1.2 1.0 1 0 0 1 1 1 1 Ribonuclease HII Inhibitor_I9 PF05922.11 AJZ76424.1 - 0.25 11.9 1.7 0.52 10.9 0.4 2.1 2 1 0 2 2 2 0 Peptidase inhibitor I9 Fibrillarin PF01269.12 AJZ76425.1 - 4.5e-85 284.2 0.1 5.3e-85 283.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin PCMT PF01135.14 AJZ76425.1 - 7.4e-05 22.3 0.0 9.3e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.5 AJZ76425.1 - 0.0053 16.3 0.0 0.0068 15.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 AJZ76425.1 - 0.0057 17.2 0.0 0.01 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF4651 PF15513.1 AJZ76425.1 - 0.062 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) Methyltransf_31 PF13847.1 AJZ76425.1 - 0.069 12.7 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DHO_dh PF01180.16 AJZ76426.1 - 1.6e-53 181.5 0.5 1.8e-53 181.4 0.4 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.12 AJZ76426.1 - 1e-06 27.8 0.1 0.00072 18.4 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 AJZ76426.1 - 1.8e-05 24.1 0.4 0.0028 16.9 0.0 2.2 2 0 0 2 2 2 2 Histidine biosynthesis protein DUF561 PF04481.7 AJZ76426.1 - 0.00028 19.8 2.8 0.00078 18.4 0.1 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF561) G3P_antiterm PF04309.7 AJZ76426.1 - 0.00058 18.9 0.5 0.5 9.3 0.0 2.3 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator IMPDH PF00478.20 AJZ76426.1 - 0.0019 17.1 0.4 0.0019 17.1 0.3 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 AJZ76426.1 - 0.0022 17.2 2.6 0.0082 15.3 0.2 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase DeoC PF01791.4 AJZ76426.1 - 0.058 12.6 0.4 7.9 5.6 0.0 2.2 2 0 0 2 2 2 0 DeoC/LacD family aldolase ThiG PF05690.9 AJZ76426.1 - 0.058 12.4 4.0 1.4 7.8 0.0 2.8 1 1 2 3 3 3 0 Thiazole biosynthesis protein ThiG PcrB PF01884.12 AJZ76426.1 - 0.06 12.5 1.3 0.58 9.3 0.0 2.6 3 0 0 3 3 3 0 PcrB family FMN_dh PF01070.13 AJZ76426.1 - 0.068 11.9 0.9 0.48 9.2 0.6 2.0 1 1 0 1 1 1 0 FMN-dependent dehydrogenase Trp_syntA PF00290.15 AJZ76426.1 - 0.14 10.6 0.7 5.4 5.4 0.1 2.2 2 0 0 2 2 2 0 Tryptophan synthase alpha chain TMP-TENI PF02581.12 AJZ76426.1 - 0.15 11.1 1.0 1.1 8.3 0.1 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI NAD_binding_1 PF00175.16 AJZ76427.1 - 5.1e-14 52.7 0.1 8.9e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.4 AJZ76427.1 - 1.9e-09 36.8 7.1 3.7e-09 35.9 4.9 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.19 AJZ76427.1 - 2.6e-07 30.6 0.0 5.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_7 PF13241.1 AJZ76427.1 - 0.027 14.7 0.0 0.065 13.4 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding DMRL_synthase PF00885.14 AJZ76427.1 - 0.12 12.0 0.2 16 5.1 0.0 2.2 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase Radical_SAM PF04055.16 AJZ76428.1 - 2.4e-10 40.8 0.0 1.4e-09 38.3 0.0 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Ribosomal_S30 PF04758.9 AJZ76429.1 - 3.8e-07 29.7 7.9 1.4e-06 27.9 5.5 2.0 1 1 0 1 1 1 1 Ribosomal protein S30 Conotoxin PF02950.12 AJZ76430.1 - 0.07 13.9 0.1 0.085 13.6 0.1 1.1 1 0 0 1 1 1 0 Conotoxin CRCB PF02537.10 AJZ76431.1 - 2.7e-24 85.2 12.0 3e-24 85.1 8.3 1.0 1 0 0 1 1 1 1 CrcB-like protein RIC3 PF15361.1 AJZ76432.1 - 0.024 14.8 0.2 0.038 14.2 0.1 1.4 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 HMG_box_2 PF09011.5 AJZ76432.1 - 0.086 13.2 1.0 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 HMG-box domain YfbU PF03887.9 AJZ76432.1 - 0.11 12.0 2.4 0.14 11.6 1.7 1.2 1 0 0 1 1 1 0 YfbU domain Rad51 PF08423.6 AJZ76435.1 - 5.9e-94 313.7 0.2 8.8e-94 313.1 0.0 1.3 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 AJZ76435.1 - 3.4e-11 42.9 0.0 5.2e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 AJZ76435.1 - 1.2e-10 40.9 0.0 1.5e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 AJZ76435.1 - 1.4e-08 34.1 0.0 2.7e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 AJZ76435.1 - 6.6e-08 32.6 0.1 4.9e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.1 AJZ76435.1 - 0.035 14.2 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AJZ76435.1 - 0.086 12.4 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 AJZ76435.1 - 0.16 11.5 0.5 0.27 10.7 0.1 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_L21e PF01157.13 AJZ76436.1 - 1.5e-13 50.3 1.6 1.9e-13 50.0 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_pol_Rpb4 PF03874.11 AJZ76437.1 - 9.9e-16 57.8 2.3 1.6e-15 57.0 1.6 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 Integrase_Zn PF02022.14 AJZ76437.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Integrase Zinc binding domain DUF2305 PF10230.4 AJZ76437.1 - 0.19 11.1 0.5 0.22 10.9 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF655 PF04919.7 AJZ76438.1 - 2.7e-53 180.3 0.4 3.1e-53 180.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.1 AJZ76438.1 - 9.3e-06 25.6 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.2 AJZ76438.1 - 0.00017 21.4 0.1 0.00059 19.7 0.0 1.9 2 1 1 3 3 3 1 Helix-hairpin-helix motif 4HB_MCP_1 PF12729.2 AJZ76438.1 - 0.28 10.5 1.8 1.7 7.9 1.2 2.0 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction RrnaAD PF00398.15 AJZ76439.1 - 1.4e-42 145.5 0.2 1.7e-42 145.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 AJZ76439.1 - 0.00014 21.4 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_L17 PF01196.14 AJZ76439.1 - 0.0042 17.6 0.3 0.033 14.7 0.2 2.4 1 1 0 1 1 1 1 Ribosomal protein L17 Methyltransf_23 PF13489.1 AJZ76439.1 - 0.0061 16.2 0.0 0.01 15.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJZ76439.1 - 0.0097 16.4 0.0 0.019 15.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain RRF PF01765.14 AJZ76439.1 - 0.051 13.0 0.8 0.077 12.4 0.6 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Methyltransf_26 PF13659.1 AJZ76439.1 - 0.068 13.2 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Radical_SAM PF04055.16 AJZ76439.1 - 0.14 12.3 0.3 3.8 7.6 0.0 2.4 1 1 2 3 3 3 0 Radical SAM superfamily MTS PF05175.9 AJZ76440.1 - 5.3e-12 45.4 0.0 8.9e-12 44.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 AJZ76440.1 - 1.1e-08 34.7 0.1 5.3e-08 32.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJZ76440.1 - 1.9e-07 30.9 0.0 2.8e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AJZ76440.1 - 1.4e-05 25.1 0.0 3.9e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 AJZ76440.1 - 3e-05 23.1 0.0 3.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 AJZ76440.1 - 0.00092 19.6 0.0 0.0086 16.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AJZ76440.1 - 0.0016 18.0 0.0 0.0036 16.8 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.7 AJZ76440.1 - 0.0035 16.2 0.0 0.0048 15.8 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_18 PF12847.2 AJZ76440.1 - 0.0042 17.6 0.0 0.013 16.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJZ76440.1 - 0.014 15.8 0.1 0.33 11.4 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 AJZ76440.1 - 0.046 12.8 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 AJZ76440.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Iso_dh PF00180.15 AJZ76441.1 - 4.5e-77 259.3 0.0 5.4e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Metallophos_2 PF12850.2 AJZ76442.1 - 1e-18 67.6 0.0 1.3e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AJZ76442.1 - 5.3e-18 65.1 0.0 7.2e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 AJZ76442.1 - 2.7e-05 23.4 0.1 0.00012 21.3 0.0 1.9 1 1 1 2 2 2 1 Metallophosphoesterase, calcineurin superfamily DUF2124 PF09897.4 AJZ76442.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) DoxX PF07681.7 AJZ76443.1 - 1.6e-14 54.0 6.3 1.6e-14 54.0 4.3 1.7 2 0 0 2 2 2 1 DoxX DoxX_2 PF13564.1 AJZ76443.1 - 1.9e-06 27.7 6.7 2.6e-06 27.3 4.6 1.2 1 0 0 1 1 1 1 DoxX-like family DoxD PF04173.8 AJZ76443.1 - 4.8e-05 23.0 3.3 4.8e-05 23.0 2.3 1.4 1 1 0 1 1 1 1 TQO small subunit DoxD DUF2892 PF11127.3 AJZ76443.1 - 7 6.5 8.0 47 3.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) HCR PF07111.7 AJZ76444.1 - 0.0072 14.4 0.1 0.0079 14.2 0.1 1.0 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) DUF904 PF06005.7 AJZ76444.1 - 0.016 15.4 0.2 0.017 15.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 AJZ76444.1 - 0.019 14.7 0.7 0.026 14.3 0.0 1.5 2 0 0 2 2 2 0 Basic region leucine zipper HR1 PF02185.11 AJZ76444.1 - 0.02 14.6 0.3 0.021 14.5 0.2 1.1 1 0 0 1 1 1 0 Hr1 repeat Prefoldin_2 PF01920.15 AJZ76444.1 - 0.023 14.4 0.2 0.028 14.2 0.1 1.1 1 0 0 1 1 1 0 Prefoldin subunit TSC22 PF01166.13 AJZ76444.1 - 0.028 14.3 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF1192 PF06698.6 AJZ76444.1 - 0.033 13.9 1.1 0.061 13.1 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) RmuC PF02646.11 AJZ76444.1 - 0.042 12.6 0.1 0.046 12.5 0.1 1.0 1 0 0 1 1 1 0 RmuC family Sipho_Gp157 PF05565.6 AJZ76444.1 - 0.044 13.3 0.3 0.049 13.2 0.2 1.0 1 0 0 1 1 1 0 Siphovirus Gp157 KCNQ_channel PF03520.9 AJZ76444.1 - 0.052 12.8 0.1 0.055 12.7 0.1 1.1 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel GvpK PF05121.7 AJZ76444.1 - 0.063 13.1 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle protein K WEMBL PF05701.6 AJZ76444.1 - 0.063 11.7 0.4 0.068 11.6 0.2 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TBPIP PF07106.8 AJZ76444.1 - 0.065 12.7 0.2 0.071 12.6 0.1 1.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WD40_alt PF14077.1 AJZ76444.1 - 0.071 12.7 0.9 0.25 11.0 0.6 1.9 1 1 0 1 1 1 0 Alternative WD40 repeat motif Med9 PF07544.8 AJZ76444.1 - 0.089 12.5 0.2 0.12 12.1 0.1 1.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 IPP-2 PF04979.9 AJZ76444.1 - 0.094 12.9 0.0 0.096 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) DUF3972 PF13118.1 AJZ76444.1 - 0.11 12.5 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) HAUS-augmin3 PF14932.1 AJZ76444.1 - 0.12 11.5 0.2 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 bZIP_1 PF00170.16 AJZ76444.1 - 0.12 12.3 0.6 0.17 11.8 0.4 1.3 1 1 0 1 1 1 0 bZIP transcription factor THOC7 PF05615.8 AJZ76444.1 - 0.12 12.6 0.4 0.13 12.5 0.3 1.0 1 0 0 1 1 1 0 Tho complex subunit 7 DUF972 PF06156.8 AJZ76444.1 - 0.12 12.6 0.1 0.14 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Cep57_CLD_2 PF14197.1 AJZ76444.1 - 0.13 12.1 1.0 0.3 11.0 0.5 1.5 1 1 1 2 2 1 0 Centrosome localisation domain of PPC89 FlaC_arch PF05377.6 AJZ76444.1 - 0.15 11.9 0.5 0.24 11.2 0.3 1.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) TPD52 PF04201.10 AJZ76444.1 - 0.17 11.6 0.6 0.19 11.4 0.4 1.2 1 1 0 1 1 1 0 Tumour protein D52 family DivIC PF04977.10 AJZ76444.1 - 0.17 11.4 1.5 0.31 10.5 1.1 1.5 1 1 0 1 1 1 0 Septum formation initiator Transglut_core2 PF13369.1 AJZ76445.1 - 1.8e-42 144.3 0.0 2.8e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.1 AJZ76445.1 - 6.6e-21 73.9 0.8 1e-20 73.3 0.6 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 AJZ76445.1 - 1.3e-05 24.7 1.2 0.00066 19.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ76445.1 - 1.9e-05 24.4 1.3 0.0018 18.1 1.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 AJZ76445.1 - 2.2e-05 23.8 2.5 0.00077 18.9 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJZ76445.1 - 6.6e-05 22.7 1.6 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.1 AJZ76445.1 - 8.3e-05 22.1 1.1 0.00019 21.0 0.7 1.6 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 AJZ76445.1 - 0.00032 21.0 0.3 0.039 14.5 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ76445.1 - 0.021 14.6 0.2 0.021 14.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 AJZ76445.1 - 0.083 13.5 0.3 0.5 11.1 0.2 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 AJZ76445.1 - 0.092 12.8 0.3 4 7.6 0.1 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RhoGEF PF00621.15 AJZ76446.1 - 0.027 14.3 1.5 0.095 12.5 0.0 2.4 2 1 0 2 2 2 0 RhoGEF domain HHH_4 PF14490.1 AJZ76446.1 - 0.18 11.5 1.9 0.97 9.2 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix containing domain Methyltransf_11 PF08241.7 AJZ76448.1 - 2.9e-07 30.8 0.0 4.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJZ76448.1 - 3.3e-06 26.8 0.0 9.4e-06 25.4 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Trm112p PF03966.11 AJZ76448.1 - 3.9e-05 23.9 0.6 0.0015 18.8 0.3 2.7 2 0 0 2 2 2 1 Trm112p-like protein Methyltransf_18 PF12847.2 AJZ76448.1 - 0.00016 22.2 0.0 0.00028 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJZ76448.1 - 0.00056 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AJZ76448.1 - 0.0043 16.4 0.0 0.0082 15.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 AJZ76448.1 - 0.022 15.1 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 AJZ76448.1 - 0.032 13.6 0.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) Topoisom_I_N PF02919.10 AJZ76450.1 - 2.6e-65 219.7 6.0 2.6e-65 219.7 4.1 2.3 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 AJZ76450.1 - 6.5e-63 211.9 5.5 1.1e-62 211.2 3.8 1.3 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 AJZ76450.1 - 2.6e-22 78.2 2.5 2.6e-22 78.2 1.7 2.5 2 0 0 2 2 2 1 C-terminal topoisomerase domain W2 PF02020.13 AJZ76450.1 - 0.00066 19.5 3.3 0.0018 18.1 0.1 2.9 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF972 PF06156.8 AJZ76450.1 - 2.7 8.3 5.6 1.3 9.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) adh_short PF00106.20 AJZ76451.1 - 2.5e-32 112.0 0.0 3.2e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AJZ76451.1 - 3.3e-21 76.1 0.0 4.1e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AJZ76451.1 - 7.8e-13 48.4 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 AJZ76451.1 - 9.1e-08 31.5 0.0 6.4e-07 28.7 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 AJZ76451.1 - 0.0011 18.2 0.1 0.0034 16.6 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 AJZ76451.1 - 0.015 15.0 0.1 0.046 13.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 AJZ76451.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 AJZ76451.1 - 0.023 14.1 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Filamin PF00630.14 AJZ76452.1 - 0.0052 17.3 2.9 0.0094 16.5 2.0 1.5 1 1 0 1 1 1 1 Filamin/ABP280 repeat CDC45 PF02724.9 AJZ76452.1 - 0.029 12.4 1.9 0.031 12.3 1.3 1.0 1 0 0 1 1 1 0 CDC45-like protein AIF_C PF14721.1 AJZ76452.1 - 0.11 12.7 3.3 0.22 11.7 1.7 1.9 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MecA PF05389.7 AJZ76452.1 - 0.57 9.6 4.9 0.75 9.2 3.4 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) YqfQ PF14181.1 AJZ76452.1 - 2.1 8.3 9.2 2.9 7.8 6.4 1.3 1 0 0 1 1 1 0 YqfQ-like protein HTH_24 PF13412.1 AJZ76453.1 - 9.2e-16 56.9 0.3 1.2e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 AJZ76453.1 - 2.3e-15 55.9 0.1 4.8e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 AJZ76453.1 - 1.6e-07 31.0 0.0 0.013 15.2 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_34 PF13601.1 AJZ76453.1 - 1e-06 28.6 0.1 0.0079 16.1 0.0 2.2 2 0 0 2 2 2 2 Winged helix DNA-binding domain Sulfolobus_pRN PF05584.6 AJZ76453.1 - 1.7e-06 27.9 0.1 0.00048 20.0 0.1 2.3 2 0 0 2 2 2 1 Sulfolobus plasmid regulatory protein MarR PF01047.17 AJZ76453.1 - 2.7e-05 23.7 0.6 0.13 12.0 0.1 2.7 2 1 0 2 2 2 2 MarR family MarR_2 PF12802.2 AJZ76453.1 - 0.00012 21.6 0.0 0.22 11.1 0.0 2.4 2 1 0 2 2 2 2 MarR family HTH_IclR PF09339.5 AJZ76453.1 - 0.00017 21.1 0.0 0.3 10.7 0.0 2.3 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_36 PF13730.1 AJZ76453.1 - 0.0012 18.8 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_40 PF14493.1 AJZ76453.1 - 0.0039 17.3 1.6 0.51 10.5 0.3 2.2 1 1 1 2 2 2 1 Helix-turn-helix domain HxlR PF01638.12 AJZ76453.1 - 0.0041 16.7 0.3 0.078 12.6 0.1 2.2 2 0 0 2 2 2 1 HxlR-like helix-turn-helix TrmB PF01978.14 AJZ76453.1 - 0.0076 15.9 0.1 0.27 10.9 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB RepL PF05732.6 AJZ76453.1 - 0.012 14.7 0.1 0.019 14.1 0.1 1.4 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) HTH_38 PF13936.1 AJZ76453.1 - 0.029 13.9 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_45 PF14947.1 AJZ76453.1 - 0.04 13.7 0.3 10 5.9 0.0 2.4 2 1 0 2 2 2 0 Winged helix-turn-helix LexA_DNA_bind PF01726.11 AJZ76453.1 - 0.046 13.2 0.1 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 LexA DNA binding domain DUF2802 PF10975.3 AJZ76453.1 - 0.11 12.2 0.0 2.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DUF4625 PF15418.1 AJZ76456.1 - 0.012 15.7 1.0 16 5.6 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4625) SpoIIIAH PF12685.2 AJZ76457.1 - 0.0093 15.4 2.7 0.014 14.8 1.8 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein Serine_rich PF08824.5 AJZ76457.1 - 0.053 13.2 0.8 0.19 11.4 0.0 1.9 1 1 1 2 2 2 0 Serine rich protein interaction domain Ly49 PF08391.5 AJZ76457.1 - 0.059 13.5 0.9 0.073 13.2 0.6 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region IncA PF04156.9 AJZ76457.1 - 0.06 12.9 0.6 0.079 12.5 0.4 1.1 1 0 0 1 1 1 0 IncA protein DUF1044 PF06296.7 AJZ76457.1 - 0.19 11.5 7.5 0.053 13.3 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1044) AIF_C PF14721.1 AJZ76457.1 - 0.39 10.9 2.6 0.45 10.7 1.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4446 PF14584.1 AJZ76457.1 - 5.1 6.9 7.3 20 4.9 5.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DEAD PF00270.24 AJZ76458.1 - 1.7e-30 105.7 0.1 3.6e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 AJZ76458.1 - 5.4e-13 49.3 0.1 1.6e-12 47.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 AJZ76458.1 - 1e-12 47.7 0.4 1e-08 34.9 0.1 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DUF2325 PF10087.4 AJZ76458.1 - 0.00044 20.0 0.2 0.025 14.4 0.0 3.7 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2325) SNF2_N PF00176.18 AJZ76458.1 - 0.0018 17.1 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain UPF0029 PF01205.14 AJZ76458.1 - 0.078 12.6 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 N6_N4_Mtase PF01555.13 AJZ76460.1 - 1.8e-36 125.7 5.0 2.2e-36 125.5 3.5 1.0 1 0 0 1 1 1 1 DNA methylase Methyltransf_26 PF13659.1 AJZ76460.1 - 3.3e-09 36.7 0.0 4.9e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain UPF0020 PF01170.13 AJZ76460.1 - 0.0001 21.9 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 AJZ76460.1 - 0.00099 18.2 0.1 0.086 11.9 0.1 2.1 2 0 0 2 2 2 2 N-6 DNA Methylase MTS PF05175.9 AJZ76460.1 - 0.05 12.9 0.0 0.17 11.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain MttA_Hcf106 PF02416.11 AJZ76461.1 - 1.3e-07 30.6 0.0 1.8e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 mttA/Hcf106 family Lip_A_acyltrans PF03279.8 AJZ76461.1 - 0.0019 17.1 0.0 0.0023 16.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase Vps51 PF08700.6 AJZ76461.1 - 0.096 12.5 0.1 0.18 11.6 0.0 1.4 2 0 0 2 2 2 0 Vps51/Vps67 DUF768 PF05589.6 AJZ76462.1 - 0.011 15.6 0.0 7.3 6.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF768) CCP_MauG PF03150.9 AJZ76462.1 - 0.024 14.9 0.2 55 4.0 0.0 3.2 1 1 1 3 3 3 0 Di-haem cytochrome c peroxidase CBM_14 PF01607.19 AJZ76462.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain MFS_1 PF07690.11 AJZ76463.1 - 1.3e-36 126.0 43.0 1.9e-26 92.5 11.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 AJZ76463.1 - 0.016 15.1 0.9 0.016 15.1 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Ubie_methyltran PF01209.13 AJZ76464.1 - 2e-17 63.1 0.0 2.5e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AJZ76464.1 - 3.2e-13 49.9 0.0 4.6e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJZ76464.1 - 1.7e-08 34.3 0.0 2.4e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJZ76464.1 - 2.3e-07 30.5 0.1 1e-06 28.4 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJZ76464.1 - 7.8e-06 26.1 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJZ76464.1 - 1.2e-05 25.8 0.0 4.8e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJZ76464.1 - 1.4e-05 25.5 0.0 2.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 AJZ76464.1 - 0.0067 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.15 AJZ76464.1 - 0.021 13.9 0.0 0.038 13.0 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase NodS PF05401.6 AJZ76464.1 - 0.095 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF555 PF04475.7 AJZ76464.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF555) MTS PF05175.9 AJZ76464.1 - 0.15 11.4 0.0 0.31 10.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Pyridox_oxidase PF01243.15 AJZ76465.1 - 4.5e-05 23.3 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF385 PF04075.9 AJZ76465.1 - 0.0044 16.9 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF385) DUF2255 PF10012.4 AJZ76465.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) ELFV_dehydrog PF00208.16 AJZ76466.1 - 6.5e-72 242.0 1.5 9.1e-72 241.5 1.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 AJZ76466.1 - 3.4e-45 152.8 0.0 6.8e-45 151.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.14 AJZ76466.1 - 0.00037 19.6 0.1 0.00075 18.6 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 AJZ76466.1 - 0.0014 18.5 0.1 0.0031 17.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 AJZ76466.1 - 0.0031 17.7 0.1 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 AJZ76466.1 - 0.0036 16.8 2.6 0.019 14.5 1.8 2.1 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Malic_M PF03949.10 AJZ76466.1 - 0.011 15.2 0.3 0.017 14.6 0.2 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain AdoHcyase_NAD PF00670.16 AJZ76466.1 - 0.013 15.3 0.6 0.037 13.8 0.2 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.16 AJZ76466.1 - 0.059 13.1 0.1 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 ThiF family IlvN PF07991.7 AJZ76466.1 - 0.12 11.7 0.9 0.86 8.9 0.3 2.2 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain LEA_2 PF03168.8 AJZ76467.1 - 0.011 16.0 0.0 0.038 14.3 0.0 1.8 1 1 1 2 2 2 0 Late embryogenesis abundant protein ECH PF00378.15 AJZ76468.1 - 4.9e-70 235.4 2.3 5.5e-70 235.2 1.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Fe-S_biosyn PF01521.15 AJZ76469.1 - 1.9e-22 79.2 0.0 2.2e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Toprim_4 PF13662.1 AJZ76470.1 - 6.8e-07 29.2 0.2 1.5e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.17 AJZ76470.1 - 0.0023 17.8 0.4 0.012 15.5 0.2 2.3 2 1 0 2 2 2 1 Toprim domain Toprim_2 PF13155.1 AJZ76470.1 - 0.033 14.5 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 Toprim-like Copper-fist PF00649.13 AJZ76470.1 - 0.056 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain DUF3969 PF13108.1 AJZ76470.1 - 0.11 12.2 0.4 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) CTP-dep_RFKase PF01982.11 AJZ76471.1 - 4.6e-42 142.4 0.0 6.5e-42 141.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF120 MarR PF01047.17 AJZ76471.1 - 0.0053 16.4 0.1 0.025 14.2 0.0 2.1 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.2 AJZ76471.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.11 AJZ76471.1 - 0.055 13.0 0.2 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 LexA DNA binding domain HTH_36 PF13730.1 AJZ76471.1 - 0.056 13.5 0.1 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain CTP_transf_2 PF01467.21 AJZ76472.1 - 1.3e-10 41.5 0.0 5e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase HTH_24 PF13412.1 AJZ76472.1 - 0.06 12.7 0.2 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TP_methylase PF00590.15 AJZ76473.1 - 7.9e-19 68.1 0.0 1.4e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF357 PF04010.8 AJZ76473.1 - 8e-10 38.2 0.4 3.3e-09 36.3 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF357) Ala_racemase_C PF00842.16 AJZ76473.1 - 0.038 13.4 0.1 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Alanine racemase, C-terminal domain Peptidase_M20 PF01546.23 AJZ76474.1 - 1.7e-29 102.6 0.1 2.3e-29 102.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AJZ76474.1 - 1.5e-14 53.7 0.2 3.1e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 AJZ76474.1 - 6.3e-07 28.4 0.8 0.0069 15.1 0.1 2.9 3 1 1 4 4 4 2 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.12 AJZ76474.1 - 0.0005 19.8 0.2 0.00089 19.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 RimK PF08443.6 AJZ76475.1 - 2.7e-45 154.2 0.0 3.8e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 AJZ76475.1 - 2.8e-09 36.9 0.0 4.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GSH-S_ATP PF02955.11 AJZ76475.1 - 3.5e-08 32.7 0.1 4.7e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.9 AJZ76475.1 - 4.1e-07 30.0 0.1 7.3e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 AJZ76475.1 - 2.4e-05 23.7 0.0 5.8e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AJZ76475.1 - 3.4e-05 23.2 0.0 9.2e-05 21.8 0.0 1.9 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_5 PF13549.1 AJZ76475.1 - 0.003 16.7 0.1 0.011 15.0 0.0 1.9 2 1 0 2 2 2 1 ATP-grasp domain zinc_ribbon_4 PF13717.1 AJZ76476.1 - 0.00044 19.8 5.2 0.03 14.0 1.1 2.0 1 1 1 2 2 2 2 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 AJZ76476.1 - 0.0016 17.8 1.6 0.0072 15.7 1.0 1.9 1 1 1 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.1 AJZ76476.1 - 0.0028 17.2 1.9 0.059 12.9 0.1 2.0 1 1 0 1 1 1 1 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 AJZ76476.1 - 0.003 16.8 0.5 0.004 16.4 0.4 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding zf-HYPF PF07503.7 AJZ76476.1 - 0.0033 16.7 1.0 0.021 14.2 0.7 1.9 1 1 0 1 1 1 1 HypF finger zf-ribbon_3 PF13248.1 AJZ76476.1 - 0.0064 15.6 0.2 0.077 12.2 0.0 2.1 2 0 0 2 2 2 1 zinc-ribbon domain zf-RING_3 PF14369.1 AJZ76476.1 - 0.0079 16.1 1.4 0.016 15.1 1.0 1.5 1 1 0 1 1 1 1 zinc-finger Prok-RING_1 PF14446.1 AJZ76476.1 - 0.012 15.3 2.3 0.026 14.2 1.6 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.6 AJZ76476.1 - 0.017 14.7 0.2 0.022 14.4 0.1 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 AJZ76476.1 - 0.028 14.3 2.1 0.055 13.4 1.5 1.6 1 1 0 1 1 1 0 Zinc ribbon domain HypA PF01155.14 AJZ76476.1 - 0.036 13.7 0.1 0.037 13.7 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family A2L_zn_ribbon PF08792.5 AJZ76476.1 - 0.037 13.4 1.6 0.096 12.1 0.1 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc-ribbons_6 PF07191.7 AJZ76476.1 - 0.046 13.4 0.3 0.17 11.7 0.2 1.8 1 1 0 1 1 1 0 zinc-ribbons zf-C2H2_6 PF13912.1 AJZ76476.1 - 0.051 13.5 0.5 0.71 9.8 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CSL PF05207.8 AJZ76476.1 - 0.052 13.0 0.8 0.063 12.7 0.5 1.2 1 0 0 1 1 1 0 CSL zinc finger Zn_ribbon_recom PF13408.1 AJZ76476.1 - 0.057 13.6 0.4 0.74 10.1 0.0 2.0 1 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C4_Topoisom PF01396.14 AJZ76476.1 - 0.063 12.7 0.4 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger PhnA_Zn_Ribbon PF08274.7 AJZ76476.1 - 0.07 12.9 2.1 0.16 11.7 1.5 1.6 1 1 0 1 1 1 0 PhnA Zinc-Ribbon BssC_TutF PF08201.6 AJZ76476.1 - 0.087 12.3 0.1 11 5.6 0.0 2.0 2 0 0 2 2 2 0 BssC/TutF protein DZR PF12773.2 AJZ76476.1 - 0.13 12.1 1.0 0.31 10.9 0.7 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-IS66 PF13005.2 AJZ76476.1 - 0.13 12.2 0.5 0.88 9.5 0.0 2.2 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-TFIIB PF13453.1 AJZ76476.1 - 0.19 10.9 1.5 0.9 8.7 1.7 1.6 1 1 1 2 2 2 0 Transcription factor zinc-finger UPF0547 PF10571.4 AJZ76476.1 - 0.22 11.2 1.4 2 8.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Lar_restr_allev PF14354.1 AJZ76476.1 - 0.29 11.4 1.5 0.69 10.2 0.2 1.9 1 1 1 2 2 2 0 Restriction alleviation protein Lar ADK_lid PF05191.9 AJZ76476.1 - 0.41 10.3 1.8 0.65 9.7 0.0 1.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid HTH_AsnC-type PF13404.1 AJZ76477.1 - 1.3e-12 47.0 1.6 3.4e-12 45.6 0.7 2.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.16 AJZ76477.1 - 1.6e-12 46.9 0.2 2.3e-12 46.4 0.2 1.3 1 0 0 1 1 1 1 AsnC family HTH_24 PF13412.1 AJZ76477.1 - 2.7e-11 42.6 1.4 8.6e-11 41.0 0.4 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 AJZ76477.1 - 0.00064 19.3 1.0 0.0011 18.5 0.4 1.7 2 0 0 2 2 1 1 HTH domain Mga PF05043.8 AJZ76477.1 - 0.0013 19.0 0.1 0.0021 18.2 0.1 1.4 1 0 0 1 1 1 1 Mga helix-turn-helix domain HTH_5 PF01022.15 AJZ76477.1 - 0.0028 17.2 0.1 0.0093 15.6 0.0 1.9 2 1 1 3 3 2 1 Bacterial regulatory protein, arsR family HTH_Mga PF08280.6 AJZ76477.1 - 0.0029 17.3 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain B-block_TFIIIC PF04182.7 AJZ76477.1 - 0.004 16.9 0.6 0.052 13.3 0.1 2.1 1 1 1 2 2 2 1 B-block binding subunit of TFIIIC NapD PF03927.8 AJZ76477.1 - 0.0045 16.7 1.4 0.45 10.3 0.1 2.2 1 1 1 2 2 2 2 NapD protein HTH_20 PF12840.2 AJZ76477.1 - 0.0055 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 AJZ76477.1 - 0.008 15.4 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_27 PF13463.1 AJZ76477.1 - 0.013 15.8 0.1 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_Tnp_ISL3 PF13542.1 AJZ76477.1 - 0.013 14.6 0.0 0.028 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ACT_4 PF13291.1 AJZ76477.1 - 0.016 15.5 1.5 1.5 9.1 0.4 2.3 2 0 0 2 2 2 0 ACT domain MarR PF01047.17 AJZ76477.1 - 0.024 14.3 2.1 0.035 13.7 0.1 2.1 3 0 0 3 3 2 0 MarR family MarR_2 PF12802.2 AJZ76477.1 - 0.024 14.2 0.3 0.055 13.1 0.0 1.7 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.5 AJZ76477.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain COG2 PF06148.6 AJZ76477.1 - 0.066 13.0 0.3 0.081 12.8 0.2 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 HTH_34 PF13601.1 AJZ76477.1 - 0.067 13.2 0.1 0.17 11.9 0.0 1.7 1 1 0 1 1 1 0 Winged helix DNA-binding domain Stk19 PF10494.4 AJZ76477.1 - 0.082 12.2 0.5 0.089 12.1 0.3 1.1 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 GYD PF08734.6 AJZ76477.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.8 1 1 1 2 2 2 0 GYD domain HTH_12 PF08461.5 AJZ76477.1 - 0.13 12.0 0.2 0.32 10.7 0.1 1.8 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain TrmB PF01978.14 AJZ76477.1 - 0.24 11.1 1.0 2.9 7.6 0.1 2.1 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB Aminotran_3 PF00202.16 AJZ76478.1 - 2.2e-107 358.8 0.1 2.7e-107 358.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 AJZ76478.1 - 0.0021 17.0 0.0 0.0054 15.7 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II AA_kinase PF00696.23 AJZ76479.1 - 9.9e-35 120.2 2.9 1.1e-34 120.0 2.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family TetR_C_8 PF14278.1 AJZ76480.1 - 0.029 14.7 0.3 0.05 13.9 0.2 1.6 1 1 0 1 1 1 0 Transcriptional regulator C-terminal region N_Asn_amidohyd PF14736.1 AJZ76480.1 - 0.049 12.4 0.2 0.056 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Cas_Cmr5 PF09701.5 AJZ76480.1 - 0.2 11.8 2.4 0.25 11.5 1.6 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) DUF3698 PF12479.3 AJZ76480.1 - 0.38 10.8 4.2 0.46 10.5 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) MAS20 PF02064.10 AJZ76480.1 - 4.7 7.1 6.1 5.6 6.8 4.2 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor RimK PF08443.6 AJZ76481.1 - 2.4e-46 157.6 0.0 3e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 AJZ76481.1 - 1e-14 54.7 0.0 2e-14 53.7 0.0 1.4 2 0 0 2 2 2 1 ATP-grasp domain GSH-S_ATP PF02955.11 AJZ76481.1 - 3.9e-11 42.3 0.0 5.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_Ter PF15632.1 AJZ76481.1 - 1.5e-06 27.2 0.0 2.6e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 AJZ76481.1 - 1.7e-06 28.0 0.0 3.7e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 AJZ76481.1 - 2.6e-06 26.8 0.0 4.9e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AJZ76481.1 - 4.1e-06 26.2 0.0 1e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_5 PF13549.1 AJZ76481.1 - 6e-05 22.3 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 AJZ76481.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_2 PF08442.5 AJZ76481.1 - 0.015 14.7 0.0 0.036 13.4 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_YheCD PF14398.1 AJZ76481.1 - 0.022 13.5 0.0 0.063 12.0 0.0 1.7 2 0 0 2 2 2 0 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 AJZ76481.1 - 0.087 12.2 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus zinc_ribbon_5 PF13719.1 AJZ76482.1 - 0.0017 17.8 0.4 0.011 15.3 0.1 2.0 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AJZ76482.1 - 0.0024 17.5 0.4 0.016 14.8 0.1 2.0 2 0 0 2 2 2 1 zinc-ribbon domain zf-RING_3 PF14369.1 AJZ76482.1 - 0.0059 16.5 0.6 0.011 15.7 0.4 1.4 1 0 0 1 1 1 1 zinc-finger zf-ribbon_3 PF13248.1 AJZ76482.1 - 0.0081 15.3 1.0 0.17 11.1 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 AJZ76482.1 - 0.018 14.5 2.9 0.6 9.6 1.7 2.7 1 1 2 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit PAAR_motif PF05488.8 AJZ76482.1 - 0.048 13.6 0.1 0.049 13.6 0.1 1.1 1 0 0 1 1 1 0 PAAR motif Prok-RING_1 PF14446.1 AJZ76482.1 - 0.079 12.7 2.2 0.18 11.5 1.5 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HYPF PF07503.7 AJZ76482.1 - 0.084 12.3 0.6 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 HypF finger DUF3079 PF11278.3 AJZ76482.1 - 0.12 11.9 0.1 0.12 11.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) DZR PF12773.2 AJZ76482.1 - 0.14 12.0 0.5 0.24 11.2 0.3 1.5 1 1 0 1 1 1 0 Double zinc ribbon DNA_ligase_ZBD PF03119.11 AJZ76482.1 - 0.3 10.8 2.3 1.1 9.0 0.1 2.3 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.5 AJZ76482.1 - 0.43 10.5 1.7 0.85 9.6 1.2 1.6 1 1 0 1 1 1 0 Zinc ribbon domain Lar_restr_allev PF14354.1 AJZ76482.1 - 0.43 10.9 2.3 1.2 9.4 1.6 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.5 AJZ76482.1 - 0.47 9.9 2.9 3 7.3 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain UPF0547 PF10571.4 AJZ76482.1 - 0.55 9.9 3.2 1.5 8.6 2.2 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Arginosuc_synth PF00764.14 AJZ76483.1 - 2.2e-157 524.0 0.0 2.5e-157 523.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 AJZ76483.1 - 5.3e-06 26.1 0.0 8.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AJZ76483.1 - 0.00051 19.3 0.1 0.00098 18.4 0.0 1.5 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 AJZ76483.1 - 0.048 12.1 0.1 0.093 11.2 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase ATP_bind_3 PF01171.15 AJZ76483.1 - 0.074 12.5 0.1 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 PP-loop family NMT1_2 PF13379.1 AJZ76484.1 - 7.6e-31 107.3 0.0 9.6e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.6 AJZ76484.1 - 3.3e-20 72.6 0.1 4.5e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.2 AJZ76484.1 - 7.8e-10 38.5 0.1 1.5e-09 37.6 0.0 1.6 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 AJZ76484.1 - 5.4e-07 29.0 0.0 0.0011 18.3 0.0 2.3 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 OpuAC PF04069.7 AJZ76484.1 - 1.1e-06 28.2 0.1 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system SBP_bac_7 PF03480.8 AJZ76484.1 - 0.12 11.4 0.3 2.1 7.3 0.0 2.3 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 ABC_tran PF00005.22 AJZ76485.1 - 1.1e-30 106.6 0.0 2e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJZ76485.1 - 6.8e-12 45.9 0.0 1.5e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 AJZ76485.1 - 0.00051 19.1 0.0 0.0063 15.6 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.1 AJZ76485.1 - 0.00075 19.5 0.1 0.0017 18.3 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 AJZ76485.1 - 0.0012 19.0 0.5 0.015 15.5 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 AJZ76485.1 - 0.0048 16.1 0.2 1.6 7.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 AJZ76485.1 - 0.0062 15.7 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 AJZ76485.1 - 0.0067 17.2 0.1 0.011 16.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AJZ76485.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 AJZ76485.1 - 0.01 15.5 0.0 0.037 13.7 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 AJZ76485.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 AJZ76485.1 - 0.017 14.8 0.0 0.046 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 AJZ76485.1 - 0.019 14.3 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AJZ76485.1 - 0.019 14.5 0.0 0.06 13.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 AJZ76485.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AJZ76485.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AJZ76485.1 - 0.043 13.9 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 AJZ76485.1 - 0.055 13.9 0.0 0.15 12.5 0.0 1.7 2 0 0 2 2 1 0 Miro-like protein AAA_30 PF13604.1 AJZ76485.1 - 0.06 12.9 0.0 0.34 10.4 0.0 2.1 2 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 AJZ76485.1 - 0.076 12.9 0.1 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 AJZ76485.1 - 0.078 13.2 0.1 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain T4SS-DNA_transf PF02534.9 AJZ76485.1 - 0.083 11.4 0.1 0.44 9.0 0.0 2.0 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Adeno_IVa2 PF02456.10 AJZ76485.1 - 0.094 11.3 0.0 1.9 7.0 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein Rad17 PF03215.10 AJZ76485.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 AJZ76485.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AJZ76485.1 - 0.14 11.5 0.1 0.61 9.4 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain HemolysinCabind PF00353.14 AJZ76487.1 - 7.3e-12 44.5 67.9 0.0044 17.2 3.1 8.6 8 0 0 8 8 8 7 Hemolysin-type calcium-binding repeat (2 copies) MFS_1 PF07690.11 AJZ76488.1 - 9.7e-27 93.5 71.4 6.3e-23 81.0 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 AJZ76488.1 - 0.16 11.7 11.0 1.4 8.7 2.3 3.3 3 0 0 3 3 3 0 MFS_1 like family Plasmid_stabil PF05016.9 AJZ76489.1 - 0.0017 18.7 0.5 0.0019 18.5 0.3 1.1 1 0 0 1 1 1 1 Plasmid stabilisation system protein Pterin_bind PF00809.17 AJZ76490.1 - 3.3e-22 78.9 0.0 5.8e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding PF02310.14 AJZ76490.1 - 7.1e-20 71.0 0.0 3e-19 69.0 0.0 2.1 2 0 0 2 2 2 1 B12 binding domain Met_synt_B12 PF02965.12 AJZ76490.1 - 5.7e-18 64.8 0.0 2.5e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding_2 PF02607.12 AJZ76490.1 - 1.2e-12 47.6 0.0 5.6e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 B12 binding domain CdhD PF03599.11 AJZ76490.1 - 0.0001 20.9 0.0 0.0002 20.0 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Ribosomal_L3 PF00297.17 AJZ76490.1 - 0.032 13.6 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L3 DUF2922 PF11148.3 AJZ76490.1 - 0.054 13.1 2.7 0.25 11.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2922) Alpha_E2_glycop PF00943.14 AJZ76490.1 - 0.058 12.0 0.0 3.5 6.1 0.0 2.4 3 0 0 3 3 3 0 Alphavirus E2 glycoprotein DIRP PF06584.8 AJZ76491.1 - 0.0046 16.8 0.3 0.011 15.6 0.0 1.7 1 1 1 2 2 2 1 DIRP PGAP1 PF07819.8 AJZ76491.1 - 0.011 15.3 0.2 0.011 15.3 0.1 1.0 1 0 0 1 1 1 0 PGAP1-like protein PIG-F PF06699.6 AJZ76491.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F S-methyl_trans PF02574.11 AJZ76492.1 - 8.1e-70 235.5 0.0 9.2e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase MTHFR PF02219.12 AJZ76493.1 - 0.023 13.7 0.1 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Methylenetetrahydrofolate reductase BING4CT PF08149.6 AJZ76493.1 - 0.056 12.9 0.5 29 4.2 0.0 3.2 3 0 0 3 3 3 0 BING4CT (NUC141) domain NUDIX PF00293.23 AJZ76494.1 - 1.8e-13 50.2 0.0 2.2e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Ribosomal_L39 PF00832.15 AJZ76495.1 - 1.1e-20 72.7 8.4 1.3e-20 72.5 5.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein REV PF00424.13 AJZ76495.1 - 0.0034 17.2 2.8 0.0036 17.1 1.9 1.0 1 0 0 1 1 1 1 REV protein (anti-repression trans-activator protein) Ribosomal_L31e PF01198.14 AJZ76496.1 - 1.1e-24 85.8 0.5 1.1e-24 85.8 0.3 2.3 2 1 0 2 2 2 1 Ribosomal protein L31e GAGA_bind PF06217.7 AJZ76496.1 - 1 9.2 12.7 1.2 9.0 8.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 AJZ76496.1 - 6.2 6.6 18.3 6.4 6.5 12.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 A2M_N PF01835.14 AJZ76497.1 - 5.9e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 MG2 domain Peptidase_M66 PF10462.4 AJZ76497.1 - 0.0013 17.6 1.3 0.0023 16.8 0.9 1.3 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.19 AJZ76497.1 - 0.0056 16.4 0.0 0.0093 15.7 0.0 1.5 1 0 0 1 1 1 1 Matrixin Filamin PF00630.14 AJZ76497.1 - 0.022 15.3 0.2 0.04 14.4 0.1 1.5 1 0 0 1 1 1 0 Filamin/ABP280 repeat Reprolysin_3 PF13582.1 AJZ76497.1 - 0.032 14.7 0.1 0.079 13.4 0.1 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 AJZ76497.1 - 0.06 12.9 0.1 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease Radical_SAM PF04055.16 AJZ76498.1 - 1.2e-21 77.5 0.1 2.5e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 AJZ76498.1 - 3.2e-16 58.9 0.0 8.3e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 AJZ76498.1 - 9.6e-05 22.0 0.0 0.00033 20.3 0.0 2.0 1 0 0 1 1 1 1 TRAM domain B12-binding PF02310.14 AJZ76498.1 - 0.099 12.5 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain Lyase_1 PF00206.15 AJZ76499.1 - 1e-87 294.2 0.1 1.2e-87 293.9 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 AJZ76499.1 - 3.6e-12 46.1 0.0 1e-11 44.7 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus Cu-oxidase_3 PF07732.10 AJZ76500.1 - 5.1e-11 42.3 0.7 4.6e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 Multicopper oxidase DAZAP2 PF11029.3 AJZ76500.1 - 0.019 15.4 0.8 3.2 8.2 0.1 3.4 2 1 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) Cu-oxidase_2 PF07731.9 AJZ76500.1 - 0.12 11.9 4.5 2.7 7.5 0.2 3.0 2 2 0 2 2 2 0 Multicopper oxidase Neur_chan_memb PF02932.11 AJZ76501.1 - 4 7.2 5.6 1.8 8.4 0.5 2.1 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region 2-Hacid_dh_C PF02826.14 AJZ76502.1 - 9.4e-62 207.3 0.0 1.4e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AJZ76502.1 - 9.8e-28 96.2 0.5 1.1e-27 96.0 0.3 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AJZ76502.1 - 8.5e-06 25.7 0.3 7.9e-05 22.5 0.0 2.2 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 AJZ76502.1 - 0.0094 15.8 0.2 0.025 14.4 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 AJZ76502.1 - 0.039 14.3 0.6 0.31 11.4 0.0 2.5 2 2 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.1 AJZ76502.1 - 0.043 14.1 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain ABC2_membrane_2 PF12679.2 AJZ76503.1 - 0.13 11.1 0.7 0.26 10.1 0.5 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein TIL PF01826.12 AJZ76503.1 - 0.22 11.6 2.4 7.2 6.8 0.5 2.6 2 1 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain DivIC PF04977.10 AJZ76505.1 - 0.0036 16.7 16.1 0.063 12.7 0.9 3.5 3 0 0 3 3 3 2 Septum formation initiator DUF2937 PF11157.3 AJZ76505.1 - 0.26 10.6 2.3 0.41 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF2968 PF11180.3 AJZ76505.1 - 4.2 6.6 16.6 0.2 10.9 1.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) PspA_IM30 PF04012.7 AJZ76505.1 - 5.5 6.2 24.6 0.86 8.9 5.4 2.7 2 1 0 3 3 3 0 PspA/IM30 family DUF1664 PF07889.7 AJZ76505.1 - 7.4 6.3 13.6 1.6 8.5 0.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_L15e PF00827.12 AJZ76506.1 - 1.8e-42 145.0 4.8 2.1e-42 144.8 3.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 Redoxin PF08534.5 AJZ76507.1 - 1.4e-08 34.3 0.1 4.8e-05 22.9 0.0 2.2 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 AJZ76507.1 - 2.2e-07 30.5 0.2 2.1e-05 24.2 0.1 2.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 AJZ76507.1 - 0.0035 17.5 0.4 0.03 14.5 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain GSHPx PF00255.14 AJZ76507.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione peroxidase HEAT_2 PF13646.1 AJZ76508.1 - 1.2e-26 92.8 0.0 1.6e-19 69.9 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.11 AJZ76508.1 - 2.1e-14 52.4 0.0 5.3e-06 26.4 0.0 3.6 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat HEAT PF02985.17 AJZ76508.1 - 8.1e-14 50.4 0.0 0.018 15.0 0.0 4.2 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 AJZ76508.1 - 8.9e-13 48.3 0.0 1.6e-05 25.2 0.1 3.9 3 1 1 4 4 4 3 HEAT-like repeat Arm PF00514.18 AJZ76508.1 - 1.4e-05 24.7 0.0 0.0099 15.6 0.0 3.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 AJZ76508.1 - 0.12 10.6 0.0 0.84 7.8 0.0 2.1 1 1 1 2 2 2 0 Adaptin N terminal region AAA_23 PF13476.1 AJZ76509.1 - 4.9e-19 69.4 27.3 4.9e-19 69.4 18.9 4.2 1 1 2 3 3 3 1 AAA domain SMC_N PF02463.14 AJZ76509.1 - 5.8e-19 68.1 22.9 9.8e-12 44.5 0.2 3.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AJZ76509.1 - 1.2e-10 41.8 14.9 5.6e-06 26.5 1.8 3.6 3 1 1 4 4 4 2 AAA domain AAA_15 PF13175.1 AJZ76509.1 - 1.4e-09 37.5 44.9 0.0048 15.9 20.8 3.1 1 1 1 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.1 AJZ76509.1 - 1e-08 34.9 0.0 2.5e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 AJZ76509.1 - 1.7e-08 33.8 0.1 3.5e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 AJZ76509.1 - 0.00029 19.4 61.8 0.00038 19.0 17.2 5.0 1 1 2 3 3 3 2 AAA domain DUF258 PF03193.11 AJZ76509.1 - 0.0011 18.2 0.0 0.0043 16.2 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 AJZ76509.1 - 0.0021 18.3 19.0 0.0052 17.0 0.0 4.7 2 1 0 2 2 1 1 ABC transporter MtrB PF05440.7 AJZ76509.1 - 0.04 13.9 0.0 0.25 11.4 0.0 2.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B IncA PF04156.9 AJZ76509.1 - 0.055 13.0 46.4 1.2 8.7 10.4 3.7 1 1 3 4 4 4 0 IncA protein PHF5 PF03660.9 AJZ76509.1 - 0.056 13.5 0.4 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 PHF5-like protein Miro PF08477.8 AJZ76509.1 - 0.6 10.6 13.3 2.1 8.8 0.6 4.5 3 3 3 6 6 4 0 Miro-like protein Reo_sigmaC PF04582.7 AJZ76509.1 - 2.8 7.0 20.0 4.8 6.2 2.7 3.8 1 1 1 4 4 4 0 Reovirus sigma C capsid protein MMR_HSR1 PF01926.18 AJZ76509.1 - 5.2 7.0 11.4 0.31 11.0 1.0 3.7 3 2 0 3 3 3 0 50S ribosome-binding GTPase NPV_P10 PF05531.7 AJZ76509.1 - 6.9 6.9 23.0 0.34 11.1 0.2 5.9 3 3 2 5 5 5 0 Nucleopolyhedrovirus P10 protein vATP-synt_AC39 PF01992.11 AJZ76510.1 - 9.5e-35 120.2 5.1 1.2e-34 120.0 3.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit AsnC_trans_reg PF01037.16 AJZ76511.1 - 2.3e-16 59.2 1.1 8.4e-09 35.0 0.1 2.1 2 0 0 2 2 2 2 AsnC family MTTB PF06253.6 AJZ76511.1 - 0.068 10.9 0.1 0.088 10.5 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) NurA PF09376.5 AJZ76512.1 - 1.8e-15 57.0 0.1 3.5e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 NurA domain WW PF00397.21 AJZ76512.1 - 0.044 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 WW domain DUF4062 PF13271.1 AJZ76512.1 - 0.066 13.2 0.0 3 7.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) NadA PF02445.11 AJZ76513.1 - 7.1e-115 382.8 2.4 8.1e-115 382.6 1.7 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein HATPase_c PF02518.21 AJZ76515.1 - 2.5e-22 78.6 0.3 4.3e-22 77.9 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJZ76515.1 - 1.3e-11 44.3 0.2 1.3e-11 44.3 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJZ76515.1 - 2e-05 24.2 0.0 4.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 GHKL domain RE_AccI PF09545.5 AJZ76515.1 - 0.026 13.0 0.2 0.03 12.8 0.1 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease HATPase_c_3 PF13589.1 AJZ76515.1 - 0.066 12.8 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mer2 PF09074.5 AJZ76515.1 - 0.2 11.5 6.7 0.33 10.8 4.7 1.3 1 0 0 1 1 1 0 Mer2 DUF883 PF05957.8 AJZ76515.1 - 0.26 11.6 5.8 1.9 8.9 0.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2120 PF09893.4 AJZ76515.1 - 0.35 10.8 3.4 0.81 9.6 0.3 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Cortex-I_coil PF09304.5 AJZ76515.1 - 0.4 10.7 11.7 0.77 9.8 8.1 1.6 1 1 0 1 1 1 0 Cortexillin I, coiled coil OmpH PF03938.9 AJZ76515.1 - 0.61 10.0 7.4 0.94 9.4 5.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Snapin_Pallidin PF14712.1 AJZ76515.1 - 1.9 8.8 10.7 1.6 9.1 5.7 2.1 1 1 0 2 2 2 0 Snapin/Pallidin SHS2_Rpb7-N PF03876.12 AJZ76516.1 - 1.9e-16 59.9 0.0 5.9e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 AJZ76516.1 - 5e-13 48.9 0.0 9.6e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.1 AJZ76516.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 S1 domain H_PPase PF03030.11 AJZ76517.1 - 2.4e-223 743.2 50.7 2.8e-223 743.0 35.1 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase HxlR PF01638.12 AJZ76518.1 - 4.7e-20 71.0 0.3 5.4e-20 70.8 0.2 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.17 AJZ76518.1 - 2.5e-08 33.5 0.1 3.9e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.1 AJZ76518.1 - 2.7e-06 27.3 0.0 3.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.2 AJZ76518.1 - 3.3e-06 26.8 0.0 4.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.2 AJZ76518.1 - 6.7e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 MarR family PadR PF03551.9 AJZ76518.1 - 5.6e-05 22.8 0.2 7.1e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_24 PF13412.1 AJZ76518.1 - 6.1e-05 22.3 0.1 9.4e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF4423 PF14394.1 AJZ76518.1 - 9.4e-05 22.0 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) TrmB PF01978.14 AJZ76518.1 - 0.00011 21.8 0.1 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.1 AJZ76518.1 - 0.00025 21.2 0.0 0.0004 20.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain Fe_dep_repress PF01325.14 AJZ76518.1 - 0.00059 19.7 0.1 0.00083 19.2 0.0 1.2 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Penicillinase_R PF03965.11 AJZ76518.1 - 0.00068 19.7 0.1 0.00089 19.3 0.1 1.2 1 0 0 1 1 1 1 Penicillinase repressor HTH_Crp_2 PF13545.1 AJZ76518.1 - 0.0007 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.15 AJZ76518.1 - 0.0017 18.4 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator HTH_5 PF01022.15 AJZ76518.1 - 0.0019 17.7 0.1 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DUF2513 PF10711.4 AJZ76518.1 - 0.0036 17.3 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2513) GntR PF00392.16 AJZ76518.1 - 0.01 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family B-block_TFIIIC PF04182.7 AJZ76518.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_45 PF14947.1 AJZ76518.1 - 0.031 14.0 0.1 0.073 12.9 0.1 1.6 1 1 0 1 1 1 0 Winged helix-turn-helix Replic_Relax PF13814.1 AJZ76518.1 - 0.034 14.0 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation LexA_DNA_bind PF01726.11 AJZ76518.1 - 0.054 13.0 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 LexA DNA binding domain HTH_DeoR PF08220.7 AJZ76518.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain FUR PF01475.14 AJZ76518.1 - 0.073 12.9 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_23 PF13384.1 AJZ76518.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain DUF2250 PF10007.4 AJZ76518.1 - 0.087 12.7 0.1 0.14 12.0 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DUF2024 PF09630.5 AJZ76519.1 - 1.3e-37 127.3 1.2 1.4e-37 127.2 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) CCG PF02754.11 AJZ76519.1 - 0.028 14.4 0.1 0.04 13.9 0.1 1.2 1 0 0 1 1 1 0 Cysteine-rich domain AAA PF00004.24 AJZ76520.1 - 1.5e-92 306.6 0.0 2e-48 163.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AJZ76520.1 - 2.3e-24 85.1 1.2 6.6e-24 83.6 0.2 2.3 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 AJZ76520.1 - 1e-15 57.4 0.0 1.8e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 AJZ76520.1 - 4.3e-13 49.2 0.0 5.4e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AJZ76520.1 - 5.1e-13 49.4 0.0 0.00019 21.4 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.9 AJZ76520.1 - 9e-13 48.4 0.0 1e-07 32.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AJZ76520.1 - 2.1e-12 47.3 0.3 0.0027 17.8 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AJZ76520.1 - 1.4e-11 45.2 0.1 1.8e-05 25.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AJZ76520.1 - 3.2e-11 43.1 0.1 0.00014 21.5 0.0 4.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AJZ76520.1 - 8.1e-11 41.9 0.0 0.00044 20.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 AJZ76520.1 - 4.6e-10 39.6 0.1 0.0014 18.4 0.0 3.8 2 1 1 3 3 3 2 Archaeal ATPase CDC48_2 PF02933.12 AJZ76520.1 - 3.7e-09 36.1 0.6 8.6e-09 34.9 0.4 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.17 AJZ76520.1 - 4.4e-09 36.4 0.0 0.0014 18.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 AJZ76520.1 - 1.7e-08 34.8 0.1 0.0014 18.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AJZ76520.1 - 5.7e-08 32.0 0.0 0.01 14.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 AJZ76520.1 - 9.9e-08 31.5 0.0 0.012 15.0 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 AJZ76520.1 - 1.4e-07 31.1 3.0 0.34 10.3 0.1 4.3 2 2 0 3 3 3 3 AAA domain Sigma54_activ_2 PF14532.1 AJZ76520.1 - 2.1e-07 31.0 0.0 0.022 14.7 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 AJZ76520.1 - 2.3e-07 31.1 0.0 0.017 15.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Mg_chelatase PF01078.16 AJZ76520.1 - 2.5e-07 30.0 0.3 0.018 14.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 AJZ76520.1 - 3.9e-07 30.1 0.0 0.024 14.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AJZ76520.1 - 1.3e-06 28.0 0.3 0.082 12.6 0.0 3.0 3 0 0 3 3 2 2 Part of AAA domain TIP49 PF06068.8 AJZ76520.1 - 1.3e-06 27.3 0.0 0.0028 16.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus KaiC PF06745.8 AJZ76520.1 - 3.7e-06 26.2 0.7 0.21 10.6 0.0 3.9 2 2 2 4 4 4 2 KaiC NACHT PF05729.7 AJZ76520.1 - 6.2e-06 25.9 0.1 0.22 11.1 0.0 3.7 4 0 0 4 4 3 2 NACHT domain PhoH PF02562.11 AJZ76520.1 - 3.4e-05 23.1 0.0 0.082 12.1 0.0 3.2 2 1 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 AJZ76520.1 - 6e-05 22.7 0.1 0.48 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.10 AJZ76520.1 - 6.3e-05 21.8 0.0 0.07 11.8 0.0 2.5 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 AJZ76520.1 - 6.3e-05 22.6 0.0 0.031 13.7 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 AJZ76520.1 - 0.00023 20.6 0.0 1.1 8.6 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain ATP-synt_ab PF00006.20 AJZ76520.1 - 0.00041 19.9 0.0 0.89 9.0 0.0 2.8 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 AJZ76520.1 - 0.001 18.0 0.0 0.35 9.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 AJZ76520.1 - 0.0014 17.5 0.0 1.4 7.6 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 AJZ76520.1 - 0.0019 17.1 0.0 0.96 8.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_3 PF07726.6 AJZ76520.1 - 0.0034 16.9 0.0 2.6 7.6 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 AJZ76520.1 - 0.0037 16.9 0.0 2 7.9 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein KAP_NTPase PF07693.9 AJZ76520.1 - 0.0052 15.8 0.0 0.38 9.6 0.0 3.0 2 2 1 3 3 3 1 KAP family P-loop domain DUF2075 PF09848.4 AJZ76520.1 - 0.0057 15.6 0.0 0.7 8.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 AJZ76520.1 - 0.0058 16.2 0.0 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 AJZ76520.1 - 0.0093 15.8 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRPRB PF09439.5 AJZ76520.1 - 0.0094 15.1 0.0 1.9 7.6 0.0 2.7 3 0 0 3 3 2 1 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 AJZ76520.1 - 0.012 15.3 0.4 17 5.0 0.0 3.8 2 2 1 3 3 3 0 NTPase SKI PF01202.17 AJZ76520.1 - 0.013 15.3 0.1 5.5 6.8 0.0 2.9 3 0 0 3 3 3 0 Shikimate kinase DAP3 PF10236.4 AJZ76520.1 - 0.013 14.4 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_11 PF13086.1 AJZ76520.1 - 0.05 13.1 0.0 8.9 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 AJZ76520.1 - 0.068 13.0 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family KTI12 PF08433.5 AJZ76520.1 - 0.13 11.4 0.0 11 5.1 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 ADH_N PF08240.7 AJZ76521.1 - 4.1e-29 100.5 0.4 7.1e-29 99.7 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AJZ76521.1 - 6e-18 64.6 0.2 9.7e-18 63.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AJZ76521.1 - 4.8e-06 27.4 0.0 9.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 AJZ76521.1 - 2.8e-05 23.3 0.4 5.8e-05 22.3 0.2 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 AJZ76521.1 - 0.058 13.9 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain CoA_binding PF02629.14 AJZ76521.1 - 0.29 11.6 3.2 0.63 10.5 1.4 2.2 2 1 0 2 2 2 0 CoA binding domain Usp PF00582.21 AJZ76523.1 - 3.3e-30 105.0 0.0 3.8e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family HpcH_HpaI PF03328.9 AJZ76523.1 - 0.019 13.8 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family CoA_binding PF02629.14 AJZ76524.1 - 2.4e-21 76.0 4.9 5.2e-21 74.9 0.9 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 AJZ76524.1 - 2.3e-12 46.7 0.5 7.6e-12 45.0 0.1 2.0 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 AJZ76524.1 - 3.2e-08 33.2 0.0 5.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 AJZ76524.1 - 2.7e-06 27.5 0.0 5.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 AJZ76524.1 - 0.00033 21.1 0.2 0.00066 20.1 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ribul_P_3_epim PF00834.14 AJZ76524.1 - 0.046 12.8 0.1 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family CARDB PF07705.6 AJZ76525.1 - 0.00091 19.2 0.2 0.0039 17.2 0.0 2.0 2 1 0 2 2 2 1 CARDB MF_alpha_N PF05436.6 AJZ76525.1 - 0.0072 15.9 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus Transglut_C PF00927.17 AJZ76525.1 - 0.008 16.2 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase family, C-terminal ig like domain FixG_C PF11614.3 AJZ76525.1 - 0.15 12.2 0.9 17 5.5 0.1 2.3 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase EamA PF00892.15 AJZ76527.1 - 5.9e-28 97.4 34.0 5.8e-16 58.6 9.2 2.7 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 AJZ76527.1 - 0.00018 21.1 8.8 0.00018 21.1 6.1 3.4 2 2 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 AJZ76527.1 - 0.00092 19.3 26.6 0.041 14.0 7.8 3.0 2 2 1 3 3 3 2 Multidrug resistance efflux transporter Acyl_transf_3 PF01757.17 AJZ76527.1 - 0.0062 15.4 21.3 0.18 10.6 10.3 2.7 1 1 1 2 2 2 2 Acyltransferase family DUF2663 PF10864.3 AJZ76527.1 - 0.56 10.4 5.5 0.38 10.9 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) DAP10 PF07213.6 AJZ76527.1 - 8.1 6.2 8.5 3.4 7.4 0.1 3.6 3 1 1 4 4 4 0 DAP10 membrane protein DRMBL PF07522.9 AJZ76528.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.7 AJZ76528.1 - 0.0035 17.1 0.0 0.0098 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 AJZ76528.1 - 0.07 12.6 1.5 4.9 6.6 1.4 2.8 2 1 0 2 2 2 0 Beta-lactamase superfamily domain AsnC_trans_reg PF01037.16 AJZ76529.1 - 1.1e-09 37.8 0.0 1.2e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 AsnC family HD_4 PF13328.1 AJZ76530.1 - 4.2e-07 29.7 0.0 5.7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 HD domain zf-C4H2 PF10146.4 AJZ76530.1 - 0.0074 16.3 1.1 0.0091 16.0 0.8 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein Arginase PF00491.16 AJZ76531.1 - 3.8e-59 200.2 0.1 4.3e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF4147 PF13660.1 AJZ76532.1 - 5.9e-70 235.0 0.2 8.2e-70 234.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.8 AJZ76532.1 - 4.1e-28 97.6 0.4 1e-27 96.3 0.3 1.7 1 0 0 1 1 1 1 MOFRL family Adenine_deam_C PF13382.1 AJZ76532.1 - 0.012 14.7 0.4 0.036 13.2 0.1 1.9 3 0 0 3 3 3 0 Adenine deaminase C-terminal domain CPSase_L_D2 PF02786.12 AJZ76533.1 - 1.2e-103 344.8 0.0 3.9e-73 245.2 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 AJZ76533.1 - 2.9e-41 140.0 0.2 6.7e-41 138.9 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 AJZ76533.1 - 1.2e-35 122.8 0.0 8.6e-17 61.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 AJZ76533.1 - 4.7e-24 84.7 0.0 7.6e-12 44.6 0.0 3.5 2 2 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_chain PF00289.17 AJZ76533.1 - 8.9e-20 70.8 0.0 7.2e-15 55.0 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp PF02222.17 AJZ76533.1 - 1.5e-17 63.5 0.1 5.3e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 AJZ76533.1 - 7.3e-15 54.6 0.1 4.8e-14 52.0 0.1 2.6 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 AJZ76533.1 - 2.6e-13 49.8 0.2 7e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus GARS_A PF01071.14 AJZ76533.1 - 2.8e-09 36.8 0.1 0.00029 20.4 0.0 2.9 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 AJZ76533.1 - 3.6e-05 23.6 0.2 0.25 11.1 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.1 AJZ76533.1 - 0.0006 19.1 0.0 0.063 12.4 0.0 2.7 2 1 1 3 3 3 1 ATP-grasp domain ATP-grasp_2 PF08442.5 AJZ76533.1 - 0.0011 18.3 0.3 0.0058 16.0 0.1 2.4 2 0 0 2 2 2 1 ATP-grasp domain Spindle_Spc25 PF08234.7 AJZ76533.1 - 0.054 13.5 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 TFIIB PF00382.14 AJZ76534.1 - 3e-36 123.0 1.5 3.8e-18 65.0 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJZ76534.1 - 0.00014 21.0 0.2 0.00028 20.1 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 AJZ76534.1 - 0.07 13.0 0.4 1.6 8.6 0.0 2.5 2 1 1 3 3 3 0 Cyclin, C-terminal domain RNA_POL_M_15KD PF02150.11 AJZ76534.1 - 0.11 12.1 0.2 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zinc_ribbon_6 PF14599.1 AJZ76535.1 - 0.0014 18.3 2.1 0.0058 16.3 1.6 1.7 1 1 1 2 2 2 1 Zinc-ribbon OrfB_Zn_ribbon PF07282.6 AJZ76535.1 - 0.25 11.0 2.4 0.28 10.8 1.7 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.8 AJZ76535.1 - 0.69 9.4 4.8 2.8 7.4 3.3 1.9 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit ADK_lid PF05191.9 AJZ76535.1 - 0.82 9.3 5.0 1.2 8.8 3.5 1.3 1 0 0 1 1 1 0 Adenylate kinase, active site lid Metallophos PF00149.23 AJZ76536.1 - 1.2e-06 28.1 0.2 4.2e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AJZ76536.1 - 0.00027 20.7 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DNA_pol_E_B PF04042.11 AJZ76536.1 - 0.056 12.6 0.1 0.27 10.4 0.0 2.1 2 1 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B ATP-synt_8 PF00895.15 AJZ76537.1 - 0.054 13.7 0.2 0.054 13.7 0.1 2.4 2 1 0 2 2 2 0 ATP synthase protein 8 SLT_beta PF02258.11 AJZ76537.1 - 0.078 12.8 0.1 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Shiga-like toxin beta subunit Cation_ATPase_C PF00689.16 AJZ76537.1 - 0.25 10.8 9.6 0.45 10.0 6.5 1.6 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus ALS_ss_C PF10369.4 AJZ76538.1 - 2.2e-25 88.1 0.2 2.6e-22 78.2 0.0 2.2 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT_5 PF13710.1 AJZ76538.1 - 2.1e-15 56.2 0.2 1.5e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 ACT domain ACT PF01842.20 AJZ76538.1 - 7.2e-15 54.1 0.1 1.5e-14 53.0 0.0 1.6 1 1 0 1 1 1 1 ACT domain ACT_4 PF13291.1 AJZ76538.1 - 2.8e-07 30.7 0.5 5.6e-07 29.8 0.3 1.4 1 0 0 1 1 1 1 ACT domain Med18 PF09637.5 AJZ76538.1 - 0.052 13.0 0.1 0.08 12.4 0.1 1.3 1 1 0 1 1 1 0 Med18 protein Laminin_EGF PF00053.19 AJZ76539.1 - 0.0048 16.7 0.7 0.005 16.7 0.5 1.1 1 0 0 1 1 1 1 Laminin EGF-like (Domains III and V) DZR PF12773.2 AJZ76539.1 - 0.0076 16.0 1.7 0.0091 15.7 1.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon FeoB_C PF07664.7 AJZ76539.1 - 0.15 11.5 1.2 0.17 11.3 0.8 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus zf-ribbon_3 PF13248.1 AJZ76539.1 - 0.5 9.6 5.1 0.62 9.3 0.5 1.9 1 1 2 3 3 3 0 zinc-ribbon domain zinc_ribbon_6 PF14599.1 AJZ76539.1 - 0.54 10.0 3.2 1.9 8.3 2.2 1.8 1 1 0 1 1 1 0 Zinc-ribbon zinc_ribbon_2 PF13240.1 AJZ76539.1 - 5.9 6.5 7.2 54 3.4 5.2 2.0 1 1 1 2 2 2 0 zinc-ribbon domain DUF872 PF05915.7 AJZ76540.1 - 0.0025 17.6 0.4 0.0027 17.5 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) E1-E2_ATPase PF00122.15 AJZ76540.1 - 0.038 13.0 0.9 0.044 12.8 0.6 1.0 1 0 0 1 1 1 0 E1-E2 ATPase MFS_1 PF07690.11 AJZ76540.1 - 1 7.9 9.1 1.3 7.6 5.7 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF4014 PF13198.1 AJZ76540.1 - 8.4 6.8 6.8 3.3 8.1 2.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) Peptidase_M26_C PF07580.9 AJZ76541.1 - 0.011 14.0 0.0 0.038 12.2 0.0 1.7 2 0 0 2 2 2 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region HIT PF01230.18 AJZ76542.1 - 1.6e-24 86.2 0.5 2.1e-24 85.9 0.4 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AJZ76542.1 - 1.2e-13 51.2 0.3 1.7e-13 50.8 0.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AJZ76542.1 - 0.0018 17.9 0.2 0.0025 17.4 0.2 1.3 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Aminotran_3 PF00202.16 AJZ76543.1 - 1.1e-57 195.4 0.2 1.5e-57 194.9 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Antitoxin-MazE PF04014.13 AJZ76544.1 - 2.3e-05 24.0 0.2 5.3e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Antidote-toxin recognition MazE DUF2638 PF10937.3 AJZ76544.1 - 0.029 15.3 0.1 0.041 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) Peptidase_C11 PF03415.9 AJZ76544.1 - 0.051 12.5 0.2 0.053 12.4 0.1 1.1 1 0 0 1 1 1 0 Clostripain family eIF-1a PF01176.14 AJZ76544.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 DUF3949 PF13133.1 AJZ76544.1 - 0.16 12.2 1.8 2.2 8.5 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3949) DUF4441 PF14536.1 AJZ76544.1 - 0.26 11.2 3.3 0.42 10.5 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) AATF-Che1 PF13339.1 AJZ76545.1 - 0.027 14.6 2.7 0.048 13.8 1.8 1.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Med9 PF07544.8 AJZ76545.1 - 0.031 13.9 0.5 0.069 12.8 0.1 2.0 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DisA-linker PF10635.4 AJZ76545.1 - 0.036 13.5 0.6 0.051 13.0 0.4 1.2 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region LAGLIDADG_WhiA PF14527.1 AJZ76545.1 - 0.042 13.7 0.2 0.06 13.2 0.1 1.4 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain EMP24_GP25L PF01105.19 AJZ76545.1 - 0.072 12.8 0.8 0.094 12.4 0.5 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD GTP_EFTU_D2 PF03144.20 AJZ76546.1 - 9.5e-11 41.6 1.0 1.9e-10 40.6 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AJZ76546.1 - 1.2e-05 24.7 2.4 2.1e-05 24.0 0.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 DUF1628 PF07790.6 AJZ76547.1 - 0.017 15.8 2.5 0.036 14.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) dCMP_cyt_deam_1 PF00383.17 AJZ76548.1 - 3.9e-26 90.6 2.1 4.9e-26 90.3 1.5 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 AJZ76548.1 - 0.073 12.7 0.8 0.11 12.2 0.5 1.3 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase DEAD PF00270.24 AJZ76549.1 - 3e-20 72.4 0.0 1.6e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AJZ76549.1 - 1.1e-19 70.0 0.1 2.3e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AJZ76549.1 - 4.6e-16 59.1 0.0 2.8e-15 56.6 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AJZ76549.1 - 0.00028 20.5 0.0 0.0011 18.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain SNF2_N PF00176.18 AJZ76549.1 - 0.00041 19.2 0.0 0.0006 18.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Flavi_DEAD PF07652.9 AJZ76549.1 - 0.00063 19.5 0.0 0.0028 17.4 0.0 2.1 2 1 0 2 2 2 1 Flavivirus DEAD domain Helicase_C_2 PF13307.1 AJZ76549.1 - 0.019 14.9 0.0 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 Helicase C-terminal domain DUF2075 PF09848.4 AJZ76549.1 - 0.023 13.6 0.0 0.045 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UbiA PF01040.13 AJZ76550.1 - 4.8e-30 104.6 9.4 6.9e-30 104.1 6.5 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family Radical_SAM PF04055.16 AJZ76551.1 - 4.5e-13 49.7 0.0 1.1e-12 48.4 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 AJZ76551.1 - 3.4e-06 27.0 0.0 7.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AJZ76551.1 - 0.0015 18.6 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF4414 PF14377.1 AJZ76551.1 - 0.0081 16.0 0.2 0.021 14.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) Chorismate_bind PF00425.13 AJZ76552.1 - 5.7e-90 301.1 0.0 1.8e-88 296.1 0.0 2.3 2 1 1 3 3 3 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 AJZ76552.1 - 1.3e-17 64.1 0.0 9.2e-17 61.3 0.0 2.3 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region CD34_antigen PF06365.7 AJZ76553.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family eRF1_2 PF03464.10 AJZ76554.1 - 3.5e-29 101.8 0.0 7.1e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AJZ76554.1 - 9e-18 64.5 0.1 2.6e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 AJZ76554.1 - 3.5e-17 62.2 0.0 5.7e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 zf-FPG_IleRS PF06827.9 AJZ76554.1 - 0.18 11.4 1.5 6.9 6.4 0.2 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS CbtB PF09489.5 AJZ76555.1 - 1.3e-07 31.3 10.1 5.1e-06 26.2 7.0 2.1 1 1 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) Tad PF13400.1 AJZ76555.1 - 0.23 11.4 1.4 0.37 10.8 1.0 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like HATPase_c PF02518.21 AJZ76557.1 - 1.3e-27 95.6 0.5 3.9e-27 94.1 0.1 1.9 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJZ76557.1 - 6.4e-12 45.2 0.3 1.1e-11 44.5 0.2 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJZ76557.1 - 1.5e-06 27.8 0.1 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 AJZ76557.1 - 6.4e-06 25.8 0.1 9.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJZ76557.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Toprim PF01751.17 AJZ76558.1 - 3.9e-05 23.5 0.1 0.003 17.4 0.1 2.6 1 1 1 2 2 2 1 Toprim domain Toprim_4 PF13662.1 AJZ76558.1 - 0.00034 20.5 0.0 0.0027 17.6 0.0 2.0 1 1 0 1 1 1 1 Toprim domain Toprim_2 PF13155.1 AJZ76558.1 - 0.033 14.5 0.0 0.05 13.9 0.0 1.4 1 1 0 1 1 1 0 Toprim-like Hormone_recep PF00104.25 AJZ76559.1 - 0.097 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Viral_env_E26 PF11050.3 AJZ76560.1 - 0.069 12.3 0.2 0.078 12.1 0.1 1.2 1 0 0 1 1 1 0 Virus envelope protein E26 DUF2543 PF10820.3 AJZ76560.1 - 0.13 12.2 0.5 0.16 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) HD_3 PF13023.1 AJZ76561.1 - 2.1e-38 131.6 0.1 2.5e-38 131.4 0.1 1.0 1 0 0 1 1 1 1 HD domain HD PF01966.17 AJZ76561.1 - 4.1e-08 33.2 0.5 1.3e-07 31.5 0.4 1.8 1 1 0 1 1 1 1 HD domain TTSSLRR PF12468.3 AJZ76561.1 - 0.0026 17.2 0.2 0.0052 16.3 0.1 1.5 2 0 0 2 2 2 1 Type III secretion system leucine rich repeat protein YopR_core PF09025.5 AJZ76561.1 - 0.0065 16.4 0.7 0.01 15.8 0.5 1.4 1 0 0 1 1 1 1 YopR Core SRI PF08236.6 AJZ76562.1 - 1.1 9.2 8.3 1.9 8.4 5.7 1.3 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain RNA_polI_A34 PF08208.6 AJZ76562.1 - 1.5 8.4 14.5 1.7 8.3 10.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Guanylate_cyc PF00211.15 AJZ76563.1 - 4.2e-18 65.3 0.0 5.5e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Arc_PepC_II PF06847.6 AJZ76564.1 - 2e-12 47.3 2.1 6.3e-12 45.7 0.4 2.5 2 1 0 2 2 2 1 Archaeal Peptidase A24 C-terminus Type II Peptidase_A24 PF01478.13 AJZ76564.1 - 1.8e-05 24.8 10.1 1.8e-05 24.8 7.0 1.8 2 0 0 2 2 2 1 Type IV leader peptidase family HATPase_c PF02518.21 AJZ76565.1 - 5.4e-24 84.0 0.1 1.2e-23 82.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJZ76565.1 - 3.6e-11 42.9 0.1 9.4e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJZ76565.1 - 5.5e-07 29.2 0.0 1.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 AJZ76565.1 - 3.9e-05 23.3 0.0 9.1e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJZ76565.1 - 0.00045 19.9 0.0 0.00077 19.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain CorA PF01544.13 AJZ76565.1 - 0.62 9.0 5.5 0.88 8.5 3.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Hpr_kinase_N PF02603.11 AJZ76566.1 - 0.0015 18.1 0.2 0.0024 17.5 0.1 1.3 1 0 0 1 1 1 1 HPr Serine kinase N terminus HTH_20 PF12840.2 AJZ76566.1 - 0.0054 16.4 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 AJZ76566.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FUR PF01475.14 AJZ76566.1 - 0.031 14.2 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_24 PF13412.1 AJZ76566.1 - 0.034 13.5 0.2 0.063 12.6 0.1 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_7 PF02796.10 AJZ76566.1 - 0.067 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase FYVE_2 PF02318.11 AJZ76566.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger DUF742 PF05331.6 AJZ76566.1 - 0.098 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF742) PALP PF00291.20 AJZ76567.1 - 4.3e-45 154.2 0.0 5.6e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PK_C PF02887.11 AJZ76567.1 - 0.33 10.5 2.2 0.77 9.3 0.5 2.1 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain DsbD PF02683.10 AJZ76568.1 - 7.6e-47 159.6 19.9 8.8e-47 159.4 13.8 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.1 AJZ76568.1 - 2.3e-07 30.7 19.5 3.7e-07 30.0 13.5 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF2781 PF10914.3 AJZ76568.1 - 0.0021 17.8 2.0 0.019 14.7 0.1 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF2781) DUF2910 PF11139.3 AJZ76568.1 - 0.24 10.4 19.5 0.2 10.7 8.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2910) Peptidase_U4 PF03419.8 AJZ76568.1 - 1.4 7.9 13.5 0.065 12.3 3.1 2.1 2 0 0 2 2 2 0 Sporulation factor SpoIIGA NUDIX PF00293.23 AJZ76569.1 - 9e-13 48.0 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 AJZ76569.1 - 0.00011 21.5 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ribosomal_S8 PF00410.14 AJZ76570.1 - 2.7e-20 72.5 0.0 3.4e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Proteasome PF00227.21 AJZ76571.1 - 3.8e-54 182.8 0.2 4.9e-54 182.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AJZ76571.1 - 1.4e-14 53.0 0.5 4.6e-14 51.4 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PurS PF02700.9 AJZ76572.1 - 1.8e-13 50.2 0.0 1.9e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase FYTT PF07078.6 AJZ76572.1 - 0.056 12.7 0.1 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Forty-two-three protein CARDB PF07705.6 AJZ76573.1 - 0.089 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 CARDB Rnf-Nqr PF02508.9 AJZ76574.1 - 0.0033 17.0 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein TMEM51 PF15345.1 AJZ76574.1 - 0.0089 15.7 0.0 0.0098 15.6 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 DUF4345 PF14248.1 AJZ76574.1 - 0.11 11.9 0.2 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) SHP PF03579.8 AJZ76574.1 - 0.13 11.6 0.8 0.91 8.9 0.0 2.0 2 0 0 2 2 2 0 Small hydrophobic protein TPR_11 PF13414.1 AJZ76575.1 - 8.3e-26 89.4 1.9 3e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AJZ76575.1 - 1.7e-25 87.4 3.1 7.9e-08 31.5 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 AJZ76575.1 - 1.9e-23 80.4 1.8 2e-06 27.3 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 AJZ76575.1 - 4e-16 59.2 0.0 8e-10 39.1 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ76575.1 - 6.1e-16 58.1 2.7 8.4e-07 28.8 0.1 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AJZ76575.1 - 8.1e-13 47.7 0.1 0.0044 17.5 0.0 4.5 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 AJZ76575.1 - 1.6e-12 46.1 0.2 0.031 14.0 0.0 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ76575.1 - 3.8e-12 45.0 1.3 0.00028 20.4 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ76575.1 - 1.1e-10 41.7 0.5 4.8e-06 26.8 0.0 3.4 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 AJZ76575.1 - 1.6e-10 40.3 1.6 0.0021 18.1 0.0 4.0 5 0 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 AJZ76575.1 - 2.4e-08 34.0 0.3 1.5e-07 31.4 0.0 2.3 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AJZ76575.1 - 2.9e-08 33.4 0.0 9.7e-07 28.5 0.0 2.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 AJZ76575.1 - 3.2e-07 30.3 1.5 3.8 8.1 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat MIT PF04212.13 AJZ76575.1 - 1.4e-06 28.0 0.6 0.73 9.7 0.0 4.2 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 AJZ76575.1 - 2.7e-05 24.0 0.0 0.23 11.2 0.0 3.4 1 1 3 4 4 4 2 Domain of Unknown Function (DUF3856) TPR_3 PF07720.7 AJZ76575.1 - 3.6e-05 23.4 1.4 0.94 9.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat 4HB_MCP_1 PF12729.2 AJZ76575.1 - 0.004 16.5 0.5 0.018 14.4 0.0 2.1 2 1 1 3 3 3 1 Four helix bundle sensory module for signal transduction PPR PF01535.15 AJZ76575.1 - 0.005 16.7 1.4 8.7 6.5 0.0 4.1 5 0 0 5 5 3 0 PPR repeat TPR_10 PF13374.1 AJZ76575.1 - 0.0058 16.5 0.3 13 5.9 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TOM20_plant PF06552.7 AJZ76575.1 - 0.014 14.9 0.7 4.2 6.9 0.0 3.4 2 2 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_5 PF12688.2 AJZ76575.1 - 0.033 14.2 0.0 0.89 9.6 0.0 2.3 1 1 1 2 2 2 0 Tetratrico peptide repeat Coatomer_E PF04733.9 AJZ76575.1 - 0.078 12.1 0.8 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_4 PF07721.9 AJZ76575.1 - 0.12 12.8 0.0 3.8 8.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SRI PF08236.6 AJZ76576.1 - 0.044 13.7 0.4 0.066 13.1 0.3 1.5 1 1 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain FANCL_C PF11793.3 AJZ76576.1 - 0.077 12.9 1.2 0.097 12.6 0.4 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-CGNR PF11706.3 AJZ76576.1 - 0.13 11.7 2.6 0.26 10.8 1.8 1.5 1 1 0 1 1 1 0 CGNR zinc finger DnaJ PF00226.26 AJZ76577.1 - 1.6e-25 88.6 0.8 3.4e-25 87.5 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain EphA2_TM PF14575.1 AJZ76577.1 - 0.029 14.7 0.1 0.078 13.3 0.1 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2663 PF10864.3 AJZ76577.1 - 0.079 13.1 2.9 0.18 12.0 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF1632 PF07857.7 AJZ76577.1 - 0.13 11.4 0.3 0.19 10.9 0.0 1.4 2 0 0 2 2 2 0 CEO family (DUF1632) HJURP_C PF12347.3 AJZ76577.1 - 0.99 9.0 5.0 8.1 6.1 0.2 3.2 2 1 1 3 3 3 0 Holliday junction regulator protein family C-terminal repeat PKD PF00801.15 AJZ76579.1 - 0.0037 16.9 0.5 0.0088 15.7 0.3 1.8 1 1 0 1 1 1 1 PKD domain CARDB PF07705.6 AJZ76579.1 - 0.0072 16.3 0.8 0.011 15.8 0.6 1.3 1 0 0 1 1 1 1 CARDB Wzt_C PF14524.1 AJZ76579.1 - 0.0082 15.8 0.2 0.011 15.4 0.2 1.4 1 1 0 1 1 1 1 Wzt C-terminal domain Y_Y_Y PF07495.8 AJZ76579.1 - 0.041 13.6 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Y_Y_Y domain REJ PF02010.10 AJZ76580.1 - 5.3e-17 61.2 7.9 2.7e-06 25.9 0.0 4.3 2 2 3 5 5 5 4 REJ domain PKD PF00801.15 AJZ76580.1 - 3.5e-08 33.0 17.0 0.039 13.6 0.1 6.7 6 1 0 6 6 6 5 PKD domain Ig_3 PF13927.1 AJZ76580.1 - 0.16 12.4 4.4 23 5.5 0.1 5.2 6 0 0 6 6 6 0 Immunoglobulin domain zf-NADH-PPase PF09297.6 AJZ76581.1 - 0.011 15.2 2.5 0.061 12.8 0.4 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Laminin_EGF PF00053.19 AJZ76581.1 - 0.014 15.3 1.4 0.019 14.9 0.9 1.2 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) zinc-ribbons_6 PF07191.7 AJZ76581.1 - 0.024 14.4 0.2 0.033 13.9 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbons TFIIS_C PF01096.13 AJZ76581.1 - 0.044 13.4 5.0 0.54 9.9 0.3 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 AJZ76581.1 - 0.099 12.6 5.9 5.1 7.1 4.1 2.2 1 1 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 AJZ76581.1 - 0.13 11.9 1.6 0.18 11.5 1.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_C74 PF12387.3 AJZ76581.1 - 0.23 10.5 1.2 0.41 9.7 0.8 1.3 1 0 0 1 1 1 0 Pestivirus NS2 peptidase FYDLN_acid PF09538.5 AJZ76581.1 - 1 9.9 2.7 1.7 9.2 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn_Tnp_IS1595 PF12760.2 AJZ76581.1 - 1.2 8.9 4.7 1 9.2 0.4 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-HIT PF04438.11 AJZ76581.1 - 5.1 6.8 6.7 14 5.4 0.3 2.0 1 1 1 2 2 2 0 HIT zinc finger Prok-JAB PF14464.1 AJZ76582.1 - 8.2e-11 41.4 0.0 9.8e-11 41.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.16 AJZ76582.1 - 0.017 14.8 0.0 0.067 12.9 0.0 1.8 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RadC PF04002.10 AJZ76582.1 - 0.04 13.5 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 RadC-like JAB domain VKOR PF07884.9 AJZ76583.1 - 0.041 13.7 0.9 0.069 13.0 0.6 1.5 1 1 0 1 1 1 0 Vitamin K epoxide reductase family Proteasome PF00227.21 AJZ76585.1 - 2.1e-46 157.6 0.1 2.3e-46 157.4 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Response_reg PF00072.19 AJZ76586.1 - 7.8e-19 67.7 0.4 8.8e-19 67.5 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Hydrolase_3 PF08282.7 AJZ76587.1 - 3.2e-30 105.5 4.2 7.2e-22 78.1 1.0 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 AJZ76587.1 - 1.1e-07 32.1 2.7 1.8e-05 24.9 0.2 3.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AJZ76587.1 - 2.9e-07 30.0 0.1 0.00017 21.0 0.1 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 AJZ76587.1 - 0.00014 22.3 2.3 0.032 14.6 1.6 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase LNS2 PF08235.8 AJZ76587.1 - 0.06 12.9 0.1 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Hydrolase_like PF13242.1 AJZ76587.1 - 0.11 12.2 0.1 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like PHP_C PF13263.1 AJZ76589.1 - 2.9e-11 42.6 0.0 8.9e-11 41.1 0.0 1.9 2 0 0 2 2 2 1 PHP-associated PHP PF02811.14 AJZ76589.1 - 1.4e-05 25.0 0.0 2.4e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 PHP domain Glyco_tranf_2_4 PF13704.1 AJZ76589.1 - 0.064 13.5 0.4 0.5 10.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 SMC_N PF02463.14 AJZ76591.1 - 5.3e-65 218.7 0.0 6.3e-64 215.2 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AJZ76591.1 - 8.3e-17 61.2 0.1 1.6e-15 57.1 0.0 3.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 AJZ76591.1 - 1.2e-10 42.0 46.4 1.2e-10 42.0 32.2 6.4 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.1 AJZ76591.1 - 1.1e-08 35.4 34.9 2.9e-06 27.4 3.9 4.9 3 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 AJZ76591.1 - 5.4e-06 25.8 0.0 1.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 AJZ76591.1 - 0.00011 21.4 3.6 0.00011 21.4 2.5 5.4 2 2 2 5 5 5 2 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 AJZ76591.1 - 0.0018 18.1 12.7 0.0018 18.1 8.8 6.9 2 2 4 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.1 AJZ76591.1 - 0.011 15.8 2.8 0.011 15.8 2.0 9.4 5 3 4 9 9 9 0 Domain of unknown function (DUF4164) SbcCD_C PF13558.1 AJZ76591.1 - 0.02 14.8 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 AJZ76591.1 - 0.022 14.7 0.7 0.022 14.7 0.5 3.6 3 2 0 3 3 3 0 AAA ATPase domain DUF1231 PF06802.6 AJZ76591.1 - 0.025 13.4 0.0 0.059 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1231) FtsK_SpoIIIE PF01580.13 AJZ76591.1 - 0.44 9.9 6.7 3.3 7.1 0.0 4.2 5 0 0 5 5 5 0 FtsK/SpoIIIE family Alba PF01918.16 AJZ76593.1 - 2.8e-07 30.0 0.2 3.7e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Alba Peripla_BP_2 PF01497.13 AJZ76594.1 - 9.6e-47 159.1 0.0 1.1e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Fis1_TPR_N PF14852.1 AJZ76594.1 - 0.11 11.8 0.0 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat MFS_1 PF07690.11 AJZ76595.1 - 3.2e-27 95.1 73.5 1e-20 73.8 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 AJZ76595.1 - 0.00069 17.8 0.3 0.00069 17.8 0.2 2.6 2 1 0 2 2 2 2 Transmembrane secretion effector MFS_2 PF13347.1 AJZ76595.1 - 0.001 17.5 36.4 0.0093 14.4 2.5 2.8 1 1 1 2 2 2 2 MFS/sugar transport protein zf-C2H2_2 PF12756.2 AJZ76595.1 - 0.067 13.3 0.5 0.12 12.4 0.4 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF373 PF04123.8 AJZ76595.1 - 1.9 7.4 23.0 0.3 10.0 4.2 3.4 2 2 1 4 4 4 0 Domain of unknown function (DUF373) VP4_haemagglut PF00426.13 AJZ76596.1 - 0.05 11.5 0.1 0.064 11.2 0.0 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) FAD_oxidored PF12831.2 AJZ76597.1 - 3.1e-16 59.5 0.1 4.9e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 AJZ76597.1 - 1.2e-13 50.7 0.1 8.1e-08 31.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AJZ76597.1 - 1.2e-12 47.5 0.3 3.4e-11 42.8 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 AJZ76597.1 - 1.2e-10 40.4 0.0 3.2e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 AJZ76597.1 - 6.4e-10 38.4 0.0 1.1e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 AJZ76597.1 - 5.8e-09 35.0 0.0 0.0024 16.5 0.0 2.3 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 AJZ76597.1 - 1.1e-08 34.3 0.6 1.8e-08 33.6 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AJZ76597.1 - 3.5e-08 33.5 0.8 7.2e-08 32.5 0.5 1.8 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AJZ76597.1 - 1.5e-07 31.6 0.1 2.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AJZ76597.1 - 2.6e-07 29.8 0.3 4e-07 29.2 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 AJZ76597.1 - 1.6e-06 28.4 0.3 0.0026 18.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AJZ76597.1 - 2.4e-05 24.2 0.1 5.5e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AJZ76597.1 - 4.4e-05 22.6 0.3 8.7e-05 21.7 0.1 1.6 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 AJZ76597.1 - 6.9e-05 22.4 0.1 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 AJZ76597.1 - 0.0041 16.8 0.1 0.008 15.8 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 AJZ76597.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 AJZ76597.1 - 0.038 13.8 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 AJZ76597.1 - 0.067 12.6 0.0 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Succ_CoA_lig PF13607.1 AJZ76597.1 - 0.11 12.1 0.2 0.82 9.2 0.1 2.2 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain CRPV_capsid PF08762.5 AJZ76597.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 CRPV capsid protein like DUF4363 PF14276.1 AJZ76598.1 - 8.6e-05 22.2 14.7 0.15 11.7 0.0 5.4 6 0 0 6 6 6 3 Domain of unknown function (DUF4363) FlgD_ig PF13860.1 AJZ76598.1 - 0.017 14.8 0.0 1.2 8.9 0.0 3.1 3 0 0 3 3 3 0 FlgD Ig-like domain DUF349 PF03993.7 AJZ76598.1 - 0.018 15.1 0.8 0.65 10.2 0.1 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) DUF367 PF04034.8 AJZ76599.1 - 1.7e-34 118.1 0.0 2.1e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 AJZ76599.1 - 1.3e-06 27.8 0.0 2.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF3042 PF11240.3 AJZ76599.1 - 0.2 11.4 0.4 0.33 10.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DZR PF12773.2 AJZ76600.1 - 0.0057 16.4 0.8 0.0071 16.1 0.6 1.1 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 AJZ76600.1 - 0.02 14.3 5.1 0.14 11.7 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF1272 PF06906.6 AJZ76600.1 - 0.14 12.0 1.8 0.2 11.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-ribbon_3 PF13248.1 AJZ76600.1 - 0.22 10.7 5.6 1.5 8.1 4.0 2.0 1 1 0 1 1 1 0 zinc-ribbon domain YhfH PF14149.1 AJZ76600.1 - 0.66 9.8 3.7 1.6 8.5 2.6 1.6 1 1 0 1 1 1 0 YhfH-like protein TF_Zn_Ribbon PF08271.7 AJZ76600.1 - 0.73 9.2 5.2 5 6.5 0.1 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding zf-RING_3 PF14369.1 AJZ76600.1 - 1.2 9.1 5.0 3.9 7.5 0.5 2.1 1 1 1 2 2 2 0 zinc-finger UPF0547 PF10571.4 AJZ76600.1 - 3.7 7.3 6.0 4.5 7.0 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Radical_SAM PF04055.16 AJZ76601.1 - 5.4e-19 68.9 0.1 9.5e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily KdpD PF02702.12 AJZ76601.1 - 0.068 12.3 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain M PF02370.11 AJZ76603.1 - 1.4 9.5 7.6 0.11 12.9 1.7 2.0 2 0 0 2 2 2 0 M protein repeat Lar_restr_allev PF14354.1 AJZ76604.1 - 0.0026 18.0 16.2 0.06 13.6 0.7 3.0 1 1 1 3 3 3 2 Restriction alleviation protein Lar DnaJ_CXXCXGXG PF00684.14 AJZ76604.1 - 0.0095 15.9 13.5 0.053 13.5 9.2 2.3 1 1 1 2 2 2 2 DnaJ central domain Zn-ribbon_8 PF09723.5 AJZ76604.1 - 0.14 12.1 10.1 5.6 7.0 0.1 3.3 3 0 0 3 3 3 0 Zinc ribbon domain zf-ZPR1 PF03367.8 AJZ76604.1 - 0.22 10.6 4.0 0.29 10.2 0.1 2.1 2 0 0 2 2 2 0 ZPR1 zinc-finger domain zf-nanos PF05741.8 AJZ76604.1 - 0.34 10.9 13.2 1.5 8.8 5.9 2.6 2 1 0 2 2 2 0 Nanos RNA binding domain Rad50_zn_hook PF04423.9 AJZ76604.1 - 0.36 10.3 10.2 1.5 8.3 0.5 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif Antifungal_prot PF11402.3 AJZ76604.1 - 1.2 9.4 12.0 3.5 7.9 8.3 2.0 1 1 0 1 1 1 0 Antifungal protein zf-FPG_IleRS PF06827.9 AJZ76604.1 - 1.5 8.5 0.1 1.5 8.5 0.1 3.1 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Zn_Tnp_IS1595 PF12760.2 AJZ76604.1 - 1.8 8.4 16.3 2 8.2 2.8 3.1 1 1 2 3 3 3 0 Transposase zinc-ribbon domain Prok-RING_4 PF14447.1 AJZ76604.1 - 1.8 8.1 13.8 6.3 6.4 2.7 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Cys_rich_CPCC PF14206.1 AJZ76604.1 - 2.2 7.9 9.6 3 7.4 0.3 2.9 3 0 0 3 3 3 0 Cysteine-rich CPCC Prim_Zn_Ribbon PF08273.7 AJZ76604.1 - 2.3 8.3 16.2 3.9 7.6 0.2 3.4 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-Di19 PF05605.7 AJZ76604.1 - 2.3 8.4 16.2 18 5.5 0.1 3.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TF_Zn_Ribbon PF08271.7 AJZ76604.1 - 3.8 6.8 13.1 5.4 6.4 0.2 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding zf-C2H2_4 PF13894.1 AJZ76604.1 - 3.9 8.0 15.7 2.1 8.8 1.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-IS66 PF13005.2 AJZ76604.1 - 4.1 7.4 11.3 7 6.7 0.9 3.2 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 DUF329 PF03884.9 AJZ76604.1 - 4.6 6.8 13.9 1.4 8.4 1.6 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF329) zf-TFIIB PF13453.1 AJZ76604.1 - 4.7 6.4 12.6 6.3 6.0 0.6 3.4 2 1 1 3 3 3 0 Transcription factor zinc-finger zf-C3HC4_3 PF13920.1 AJZ76604.1 - 6.7 6.4 17.9 8.3 6.1 0.5 3.3 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-Sec23_Sec24 PF04810.10 AJZ76604.1 - 7.2 6.2 10.6 18 5.0 0.1 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger HypA PF01155.14 AJZ76604.1 - 7.3 6.3 9.2 0.51 10.0 0.9 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 AJZ76604.1 - 8.6 6.4 15.8 0.34 10.9 2.0 3.0 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.1 AJZ76604.1 - 9.9 5.5 12.4 0.98 8.7 0.6 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Aminotran_1_2 PF00155.16 AJZ76605.1 - 6.5e-57 193.1 0.0 8.6e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CM_2 PF01817.16 AJZ76605.1 - 3.1e-12 46.4 0.8 8.2e-12 45.0 0.6 1.7 1 0 0 1 1 1 1 Chorismate mutase type II Aminotran_5 PF00266.14 AJZ76605.1 - 1.1e-06 27.6 0.0 1.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AJZ76605.1 - 7.3e-06 25.3 0.0 2e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AJZ76605.1 - 5.2e-05 21.7 0.0 8.2e-05 21.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 AJZ76605.1 - 6.8e-05 21.6 0.6 0.00077 18.2 0.1 2.5 3 0 0 3 3 3 1 Allinase DegT_DnrJ_EryC1 PF01041.12 AJZ76605.1 - 0.00023 20.3 0.0 0.00033 19.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1396 PF07161.8 AJZ76605.1 - 0.00069 19.3 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1396) Leuk-A4-hydro_C PF09127.6 AJZ76605.1 - 0.064 12.8 0.4 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal GalP_UDP_transf PF01087.17 AJZ76606.1 - 1.2e-10 41.7 0.1 2.4e-08 34.2 0.0 2.7 3 0 0 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.18 AJZ76606.1 - 1.7e-08 34.8 0.0 0.0012 19.3 0.0 2.3 2 0 0 2 2 2 2 HIT domain DcpS_C PF11969.3 AJZ76606.1 - 8.4e-05 22.7 0.0 0.0021 18.2 0.0 2.2 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.12 AJZ76606.1 - 0.0062 16.0 0.0 0.015 14.8 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain zf-Di19 PF05605.7 AJZ76606.1 - 0.0079 16.3 0.1 2.6 8.2 0.0 2.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Lar_restr_allev PF14354.1 AJZ76606.1 - 0.09 13.0 0.7 0.69 10.2 0.0 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar Rad50_zn_hook PF04423.9 AJZ76606.1 - 0.13 11.7 0.3 2.4 7.6 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif PhosphMutase PF10143.4 AJZ76607.1 - 5.3e-45 153.1 0.0 7.4e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.13 AJZ76607.1 - 1.9e-30 106.0 0.0 3.8e-30 105.1 0.0 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 AJZ76607.1 - 0.004 16.5 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4358 PF14270.1 AJZ76608.1 - 0.2 11.5 2.8 0.99 9.3 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4358) Gar1 PF04410.9 AJZ76609.1 - 3e-06 26.7 0.0 3.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region TPR_1 PF00515.23 AJZ76610.1 - 3.6e-19 67.4 6.2 4.2e-06 26.1 0.0 5.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 AJZ76610.1 - 1.7e-18 66.0 2.0 5.2e-08 32.4 0.1 3.8 2 1 1 4 4 4 3 TPR repeat TPR_17 PF13431.1 AJZ76610.1 - 8.9e-15 53.5 3.0 0.0032 17.5 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ76610.1 - 2.9e-14 52.7 5.9 1.5e-05 24.8 0.2 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 AJZ76610.1 - 2.2e-12 45.7 0.4 0.087 12.6 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ76610.1 - 2.8e-11 43.5 0.1 0.00032 20.9 0.0 3.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AJZ76610.1 - 5.2e-11 42.9 0.1 0.016 15.9 0.3 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AJZ76610.1 - 1.5e-09 37.0 2.4 0.52 10.3 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 AJZ76610.1 - 3.1e-09 36.6 0.0 0.29 11.8 0.0 5.5 1 1 5 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 AJZ76610.1 - 4e-09 36.4 0.7 0.00087 19.3 0.0 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AJZ76610.1 - 6.6e-07 28.6 3.9 0.015 15.0 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 AJZ76610.1 - 4.6e-05 23.2 0.4 7.3 6.6 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.2 AJZ76610.1 - 5.8e-05 22.9 0.1 4.3 7.1 0.0 4.5 1 1 3 4 4 4 1 Domain of Unknown Function (DUF3856) BTAD PF03704.12 AJZ76610.1 - 6e-05 23.3 0.0 0.0039 17.5 0.0 2.8 1 1 2 3 3 3 2 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 AJZ76610.1 - 0.00021 21.0 0.4 0.11 12.3 0.0 4.0 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.9 AJZ76610.1 - 0.00059 19.1 0.5 0.36 9.9 0.0 2.3 1 1 0 2 2 2 2 Coatomer epsilon subunit TPR_15 PF13429.1 AJZ76610.1 - 0.0009 18.3 0.0 0.0025 16.9 0.0 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 AJZ76610.1 - 0.0013 19.0 0.1 8.3 7.1 0.0 5.1 5 1 2 7 7 7 0 Tetratricopeptide repeat MIT PF04212.13 AJZ76610.1 - 0.011 15.5 0.9 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 AJZ76610.1 - 0.037 13.8 0.0 5.1 7.0 0.0 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat MMS19_C PF12460.3 AJZ76610.1 - 0.067 11.9 0.1 0.11 11.1 0.1 1.4 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal NAD_binding_7 PF13241.1 AJZ76612.1 - 3.2e-19 69.1 0.3 9.1e-19 67.6 0.1 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 AJZ76612.1 - 1.2e-05 25.4 0.1 2.3e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 AJZ76612.1 - 0.00047 20.1 0.1 0.00097 19.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Sirohm_synth_M PF14824.1 AJZ76612.1 - 0.00096 18.0 0.0 0.0024 16.7 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central CysG_dimeriser PF10414.4 AJZ76612.1 - 0.042 13.3 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region KH_2 PF07650.12 AJZ76612.1 - 0.057 12.9 4.1 0.91 9.1 0.5 2.9 2 1 0 2 2 2 0 KH domain Arch_flagellin PF01917.11 AJZ76612.1 - 0.065 12.8 0.8 0.14 11.8 0.6 1.6 1 1 0 1 1 1 0 Archaebacterial flagellin BACK PF07707.10 AJZ76612.1 - 0.077 12.8 0.1 0.31 10.9 0.0 1.9 1 1 1 2 2 2 0 BTB And C-terminal Kelch ThiF PF00899.16 AJZ76612.1 - 0.14 11.9 0.6 0.46 10.2 0.2 1.9 1 1 1 2 2 2 0 ThiF family IlvN PF07991.7 AJZ76612.1 - 0.22 10.9 1.1 0.61 9.4 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain HD PF01966.17 AJZ76613.1 - 6.9e-16 58.3 0.4 1.1e-15 57.6 0.2 1.4 1 0 0 1 1 1 1 HD domain tRNA_anti-codon PF01336.20 AJZ76614.1 - 0.00018 21.3 0.5 0.00022 20.9 0.4 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Cadherin-like PF12733.2 AJZ76614.1 - 0.45 10.8 2.2 12 6.2 0.2 2.1 1 1 1 2 2 2 0 Cadherin-like beta sandwich domain PGK PF00162.14 AJZ76615.1 - 1.6e-110 369.3 0.4 1.8e-110 369.1 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF218 PF02698.12 AJZ76615.1 - 0.0047 16.4 0.2 0.27 10.7 0.0 2.3 2 0 0 2 2 2 2 DUF218 domain PRC PF05239.11 AJZ76616.1 - 1.1e-11 44.3 0.6 6.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 PRC-barrel domain OpcA PF07239.6 AJZ76616.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein OpcA IMP_cyclohyd PF07826.6 AJZ76617.1 - 0.036 13.4 0.1 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein CotJB PF12652.2 AJZ76617.1 - 0.089 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 CotJB protein Ribosomal_L16 PF00252.13 AJZ76619.1 - 5e-25 87.7 0.7 6.1e-25 87.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rhodanese PF00581.15 AJZ76620.1 - 2.2e-38 131.0 0.1 2.3e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Ribosomal_L18e PF00828.14 AJZ76621.1 - 3.1e-12 46.9 0.8 3.7e-12 46.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Aconitase PF00330.15 AJZ76622.1 - 8.5e-81 271.7 3.1 5.5e-55 186.6 0.3 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) FYRC PF05965.9 AJZ76623.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 F/Y rich C-terminus DAO PF01266.19 AJZ76624.1 - 1.3e-38 132.8 0.0 1.7e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 AJZ76624.1 - 1.9e-09 36.2 0.0 0.0002 19.7 0.0 2.4 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.1 AJZ76624.1 - 0.00029 20.7 0.0 0.00072 19.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AJZ76624.1 - 0.00068 18.2 0.1 0.12 10.8 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.7 AJZ76624.1 - 0.0016 17.4 0.0 1.1 8.0 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 AJZ76624.1 - 0.04 13.7 0.0 0.38 10.6 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AJZ76624.1 - 0.046 12.3 0.3 0.75 8.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.14 AJZ76624.1 - 0.049 12.6 0.1 4.1 6.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 AJZ76624.1 - 0.058 13.8 0.3 2 8.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 AJZ76624.1 - 0.14 11.5 0.1 0.66 9.4 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA OTCace_N PF02729.16 AJZ76625.1 - 3.6e-51 172.5 0.1 5.1e-51 172.0 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 AJZ76625.1 - 3.1e-47 160.3 0.1 9.2e-47 158.8 0.0 1.7 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Prefoldin PF02996.12 AJZ76626.1 - 2.7e-18 65.7 2.0 4.3e-18 65.0 1.4 1.3 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 AJZ76626.1 - 2.8e-06 27.0 0.7 2.8e-06 27.0 0.5 1.7 2 0 0 2 2 2 1 Prefoldin subunit Laminin_I PF06008.9 AJZ76626.1 - 0.0074 15.6 1.4 0.0074 15.6 1.0 1.4 2 0 0 2 2 2 1 Laminin Domain I TMF_TATA_bd PF12325.3 AJZ76626.1 - 0.014 15.0 4.3 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2524 PF10732.4 AJZ76626.1 - 0.024 14.7 1.7 0.024 14.7 1.2 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF2524) DUF948 PF06103.6 AJZ76626.1 - 0.051 13.4 0.4 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FlgN PF05130.7 AJZ76626.1 - 0.057 13.6 5.8 0.46 10.7 0.6 2.3 2 0 0 2 2 2 0 FlgN protein Reo_sigmaC PF04582.7 AJZ76626.1 - 0.12 11.4 3.4 0.29 10.2 2.4 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF1840 PF08895.6 AJZ76626.1 - 0.16 12.0 1.8 0.18 11.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) WXG100 PF06013.7 AJZ76626.1 - 0.67 9.9 5.2 3.8 7.5 0.2 2.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Sipho_Gp157 PF05565.6 AJZ76626.1 - 0.74 9.3 5.7 2.6 7.5 0.1 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 Nif11 PF07862.6 AJZ76626.1 - 0.83 9.6 5.0 0.14 12.1 0.9 1.7 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function HR1 PF02185.11 AJZ76626.1 - 1.1 9.0 5.9 6.1 6.6 3.3 2.6 2 1 0 2 2 2 0 Hr1 repeat FlaC_arch PF05377.6 AJZ76626.1 - 1.6 8.6 3.9 1.6 8.6 1.7 1.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PEPCK_ATP PF01293.15 AJZ76627.1 - 1.5e-216 719.4 0.0 1.7e-216 719.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.1 AJZ76627.1 - 0.074 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AJZ76627.1 - 0.12 11.9 0.1 0.34 10.4 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 AJZ76627.1 - 0.41 10.9 3.1 6.3 7.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain Spt5-NGN PF03439.8 AJZ76628.1 - 1.9e-21 75.5 0.0 2.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 AJZ76628.1 - 1.6e-06 27.5 0.1 3.6e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 KOW motif NusG PF02357.14 AJZ76628.1 - 0.005 17.0 0.0 0.027 14.7 0.0 2.0 1 1 0 1 1 1 1 Transcription termination factor nusG Glyco_hydro_20b PF02838.10 AJZ76628.1 - 0.01 16.3 0.4 0.047 14.2 0.1 1.9 1 1 1 2 2 2 0 Glycosyl hydrolase family 20, domain 2 AsnC_trans_reg PF01037.16 AJZ76629.1 - 4.8e-13 48.6 0.1 7.6e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 AsnC family HTH_24 PF13412.1 AJZ76629.1 - 4.5e-10 38.7 0.7 9.8e-10 37.6 0.5 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AJZ76629.1 - 5.8e-08 32.1 0.0 1.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain B-block_TFIIIC PF04182.7 AJZ76629.1 - 0.00013 21.7 0.1 0.0002 21.1 0.1 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR PF01047.17 AJZ76629.1 - 0.00062 19.4 0.1 0.0013 18.3 0.1 1.5 1 0 0 1 1 1 1 MarR family Ribosomal_S25 PF03297.10 AJZ76629.1 - 0.004 17.1 0.8 0.068 13.2 0.1 2.1 2 0 0 2 2 2 1 S25 ribosomal protein MarR_2 PF12802.2 AJZ76629.1 - 0.0082 15.7 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 AJZ76629.1 - 0.015 14.9 0.1 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 AJZ76629.1 - 0.021 14.4 0.6 0.12 12.0 0.1 2.1 2 0 0 2 2 2 0 HTH domain HTH_psq PF05225.11 AJZ76629.1 - 0.022 14.3 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_34 PF13601.1 AJZ76629.1 - 0.037 14.0 0.6 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain Rrf2 PF02082.15 AJZ76629.1 - 0.042 13.9 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator Mga PF05043.8 AJZ76629.1 - 0.049 13.9 0.1 0.097 12.9 0.1 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_27 PF13463.1 AJZ76629.1 - 0.087 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Sulfolobus_pRN PF05584.6 AJZ76629.1 - 0.091 12.7 0.3 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein DDRGK PF09756.4 AJZ76629.1 - 0.11 11.9 0.9 2.3 7.5 0.1 2.1 2 0 0 2 2 2 0 DDRGK domain UPF0126 PF03458.8 AJZ76630.1 - 2.5e-39 132.7 22.7 5.2e-20 70.8 6.2 2.7 2 1 1 3 3 3 2 UPF0126 domain RNA_pol_Rpb5_C PF01191.14 AJZ76631.1 - 1.5e-27 95.0 0.1 1.8e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain A2M_N PF01835.14 AJZ76632.1 - 0.00017 21.7 0.0 0.00032 20.8 0.0 1.5 1 0 0 1 1 1 1 MG2 domain DUF4493 PF14900.1 AJZ76632.1 - 0.0017 17.9 0.5 0.018 14.6 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4493) FlgD_ig PF13860.1 AJZ76632.1 - 0.047 13.4 1.4 0.092 12.4 0.1 2.1 3 0 0 3 3 3 0 FlgD Ig-like domain A2M_N PF01835.14 AJZ76633.1 - 0.00021 21.4 0.0 0.00052 20.2 0.0 1.7 2 0 0 2 2 2 1 MG2 domain Big_3_4 PF13754.1 AJZ76633.1 - 0.83 10.0 6.9 0.83 10.0 0.8 3.4 3 2 1 4 4 4 0 Bacterial Ig-like domain (group 3) DUF111 PF01969.12 AJZ76635.1 - 5.7e-112 374.3 3.4 6.4e-112 374.1 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 A2M_N PF01835.14 AJZ76636.1 - 0.0056 16.8 0.0 0.0097 16.1 0.0 1.3 1 0 0 1 1 1 1 MG2 domain CC PF04942.9 AJZ76636.1 - 0.018 14.9 3.5 0.062 13.1 0.7 2.7 2 0 0 2 2 2 0 CC domain EB PF01683.13 AJZ76636.1 - 0.43 10.6 3.6 7.7 6.6 0.1 2.4 2 1 0 2 2 2 0 EB module Cation_efflux PF01545.16 AJZ76637.1 - 6.6e-75 251.8 29.3 7.2e-57 192.6 9.7 3.0 2 1 1 3 3 3 3 Cation efflux family BON PF04972.12 AJZ76637.1 - 0.83 9.4 2.8 3.8 7.3 0.0 3.0 4 0 0 4 4 4 0 BON domain ATP_synt_I PF03899.10 AJZ76637.1 - 6.3 7.0 12.3 0.14 12.3 0.3 2.6 3 0 0 3 3 3 0 ATP synthase I chain Cu-oxidase_3 PF07732.10 AJZ76638.1 - 7.7e-26 90.1 8.0 3.9e-21 74.9 0.7 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AJZ76638.1 - 3.4e-19 68.7 10.6 1.1e-08 34.6 0.7 3.4 2 1 0 2 2 2 2 Multicopper oxidase RNA_pol_N PF01194.12 AJZ76639.1 - 3.6e-29 100.5 1.3 4.4e-29 100.2 0.9 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 AJZ76639.1 - 0.018 15.1 0.6 0.032 14.3 0.5 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) ADH_N PF08240.7 AJZ76640.1 - 1.8e-24 85.5 1.6 2.9e-24 84.9 1.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AJZ76640.1 - 1.2e-06 28.1 0.1 7.3e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 AJZ76640.1 - 0.0036 17.3 0.1 0.0059 16.7 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N_2 PF13602.1 AJZ76640.1 - 0.044 14.6 0.0 0.12 13.2 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_Gly3P_dh_N PF01210.18 AJZ76640.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MAF_flag10 PF01973.13 AJZ76642.1 - 3e-41 140.7 0.7 4.1e-41 140.3 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF115 TPK_catalytic PF04263.11 AJZ76642.1 - 0.0046 16.5 0.2 0.29 10.7 0.1 2.4 1 1 1 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain GATase PF00117.23 AJZ76643.1 - 3.1e-44 150.7 0.0 4.9e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 AJZ76643.1 - 8.9e-32 108.6 0.1 2e-31 107.5 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 AJZ76643.1 - 1.9e-11 43.3 0.2 4.5e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 AJZ76643.1 - 1.4e-08 34.4 0.0 5.7e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 AJZ76643.1 - 0.00015 21.3 0.0 0.00058 19.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 AJZ76643.1 - 0.00033 19.3 0.0 0.0032 16.0 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 AJZ76643.1 - 0.0011 18.4 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AJZ76643.1 - 0.0045 16.2 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 AJZ76643.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family PRANC PF09372.5 AJZ76643.1 - 0.058 13.3 0.1 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 PRANC domain Adenine_deam_C PF13382.1 AJZ76644.1 - 4e-48 162.8 0.0 8.5e-48 161.7 0.0 1.6 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.15 AJZ76644.1 - 1.2e-15 57.9 0.0 8e-13 48.7 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 AJZ76644.1 - 2.1e-11 43.4 0.1 6.4e-11 41.9 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 AJZ76644.1 - 2.4e-05 24.5 0.0 0.0025 17.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 AJZ76644.1 - 0.012 14.9 0.1 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase family CobS PF02654.10 AJZ76645.1 - 8.4e-52 176.0 16.7 9.5e-52 175.9 11.6 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase DUF1461 PF07314.6 AJZ76645.1 - 0.052 13.2 0.2 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF3040 PF11239.3 AJZ76645.1 - 4 7.5 14.8 10 6.2 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Aldedh PF00171.17 AJZ76646.1 - 1.1e-141 472.3 0.1 1.2e-141 472.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pox_E6 PF04656.7 AJZ76648.1 - 0.03 12.5 1.9 0.95 7.5 0.1 2.0 1 1 1 2 2 2 0 Pox virus E6 protein YtzH PF14165.1 AJZ76648.1 - 0.2 11.9 2.3 1.5 9.0 0.3 2.2 2 0 0 2 2 2 0 YtzH-like protein DUF720 PF05302.6 AJZ76648.1 - 0.32 10.7 14.2 0.69 9.6 7.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF720) DUF4465 PF14717.1 AJZ76648.1 - 0.46 10.8 5.8 0.28 11.5 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4465) DUF3347 PF11827.3 AJZ76648.1 - 0.53 10.2 6.5 3 7.8 4.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) LPP20 PF02169.11 AJZ76648.1 - 5.1 7.2 11.0 26 4.9 7.7 2.2 1 1 0 1 1 1 0 LPP20 lipoprotein HxlR PF01638.12 AJZ76649.1 - 4.8e-26 90.2 0.2 1.2e-25 88.9 0.0 1.6 2 0 0 2 2 2 1 HxlR-like helix-turn-helix PadR PF03551.9 AJZ76649.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Polyoma_agno PF01736.11 AJZ76649.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Polyomavirus agnoprotein MarR PF01047.17 AJZ76649.1 - 0.054 13.2 0.5 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 MarR family CCG PF02754.11 AJZ76649.1 - 0.1 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich domain CBS PF00571.23 AJZ76650.1 - 8.3e-06 25.5 0.8 0.39 10.5 0.0 3.9 4 0 0 4 4 4 2 CBS domain DUF2689 PF10894.3 AJZ76650.1 - 0.087 12.6 0.1 16 5.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2689) HTH_20 PF12840.2 AJZ76651.1 - 0.00096 18.9 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain DUF742 PF05331.6 AJZ76651.1 - 0.0068 15.9 0.0 0.009 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF742) FUR PF01475.14 AJZ76651.1 - 0.01 15.7 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Ferric uptake regulator family TrmB PF01978.14 AJZ76651.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 AJZ76651.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain DND1_DSRM PF14709.1 AJZ76651.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 CBS PF00571.23 AJZ76652.1 - 6.9e-55 182.5 10.8 3.8e-15 55.4 0.1 4.1 4 0 0 4 4 4 4 CBS domain EAP30 PF04157.11 AJZ76652.1 - 0.1 11.7 0.1 0.18 10.9 0.1 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family Usp PF00582.21 AJZ76653.1 - 4.2e-33 114.4 0.0 4.7e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Mrr_cat PF04471.7 AJZ76654.1 - 1.5e-05 24.8 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease DUF4143 PF13635.1 AJZ76654.1 - 0.00066 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4143) DUF234 PF03008.9 AJZ76654.1 - 0.011 15.9 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function HTH_5 PF01022.15 AJZ76655.1 - 4.4e-07 29.4 0.0 6.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_12 PF08461.5 AJZ76655.1 - 4.7e-05 23.0 0.1 9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_20 PF12840.2 AJZ76655.1 - 0.0011 18.7 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_rep_org_N PF09681.5 AJZ76655.1 - 0.027 14.0 0.6 0.035 13.6 0.4 1.4 1 1 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) RepL PF05732.6 AJZ76655.1 - 0.06 12.5 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) HTH_24 PF13412.1 AJZ76655.1 - 0.095 12.1 0.0 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding PUA PF01472.15 AJZ76656.1 - 1.2e-12 47.3 0.4 1.8e-12 46.7 0.3 1.3 1 0 0 1 1 1 1 PUA domain TGT_C2 PF14810.1 AJZ76656.1 - 2e-10 40.3 0.0 6.5e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Patch-forming domain C2 of tRNA-guanine transglycosylase Trm56 PF01994.11 AJZ76657.1 - 3.2e-50 168.9 0.4 4.6e-50 168.4 0.3 1.2 1 0 0 1 1 1 1 tRNA ribose 2'-O-methyltransferase, aTrm56 SpoU_methylase PF00588.14 AJZ76657.1 - 6.8e-07 29.2 0.1 8.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Condensin2nSMC PF12422.3 AJZ76657.1 - 0.0092 15.7 0.1 0.021 14.5 0.0 1.6 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit TFIIE_alpha PF02002.12 AJZ76658.1 - 1.2e-18 66.5 1.2 1.2e-18 66.5 0.8 1.9 2 0 0 2 2 2 1 TFIIE alpha subunit D5_N PF08706.6 AJZ76658.1 - 0.002 18.2 0.2 0.0027 17.8 0.1 1.2 1 0 0 1 1 1 1 D5 N terminal like TrmB PF01978.14 AJZ76658.1 - 0.016 14.8 0.1 0.042 13.5 0.0 1.7 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sigma70_r3 PF04539.11 AJZ76658.1 - 0.047 13.5 0.8 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-70 region 3 C1_2 PF03107.11 AJZ76658.1 - 0.52 10.4 3.8 4.7 7.4 2.9 2.1 1 1 1 2 2 2 0 C1 domain Lum_binding PF00677.12 AJZ76659.1 - 1.2e-45 153.3 13.7 3.7e-26 90.8 0.9 2.0 2 0 0 2 2 2 2 Lumazine binding domain DUF3159 PF11361.3 AJZ76660.1 - 0.038 13.4 0.2 0.048 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) Pro_dh PF01619.13 AJZ76661.1 - 6.6e-41 140.2 0.5 1.4e-40 139.2 0.3 1.4 1 1 0 1 1 1 1 Proline dehydrogenase HAUS4 PF14735.1 AJZ76661.1 - 0.0056 16.0 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 4 NRDD PF13597.1 AJZ76662.1 - 2.7e-18 65.3 0.0 6.1e-16 57.6 0.0 2.3 2 0 0 2 2 2 2 Anaerobic ribonucleoside-triphosphate reductase HTH_20 PF12840.2 AJZ76662.1 - 9.2e-10 38.1 0.0 2.2e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain ATP-cone PF03477.11 AJZ76662.1 - 6.2e-08 32.9 2.8 6.6e-07 29.6 0.0 3.6 4 1 0 4 4 4 1 ATP cone domain FtsA PF14450.1 AJZ76662.1 - 0.036 13.9 0.1 0.22 11.3 0.0 2.3 2 0 0 2 2 2 0 Cell division protein FtsA zf-ribbon_3 PF13248.1 AJZ76662.1 - 0.24 10.6 4.5 0.38 10.0 3.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Cas_Cas02710 PF09670.5 AJZ76663.1 - 0.15 10.6 0.1 10 4.6 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas02710) ABC-3 PF00950.12 AJZ76664.1 - 1.4e-65 221.1 34.3 1.6e-65 220.9 23.8 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.13 AJZ76664.1 - 3.8e-07 29.2 33.0 8.3e-07 28.1 22.8 1.6 1 1 0 1 1 1 1 FecCD transport family TroA PF01297.12 AJZ76665.1 - 1.9e-81 273.0 0.1 2.2e-81 272.8 0.1 1.0 1 0 0 1 1 1 1 Periplasmic solute binding protein family CheD PF03975.8 AJZ76666.1 - 6.4e-30 103.2 0.1 8.9e-30 102.7 0.0 1.2 1 0 0 1 1 1 1 CheD chemotactic sensory transduction Cu-oxidase_4 PF02578.10 AJZ76666.1 - 0.031 13.3 0.1 0.059 12.4 0.1 1.4 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase CheC PF04509.7 AJZ76667.1 - 1.2e-12 47.3 1.2 1.5e-11 43.8 0.0 2.5 3 0 0 3 3 3 1 CheC-like family CheX PF13690.1 AJZ76667.1 - 1.3e-07 31.4 0.2 7.2e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Chemotaxis phosphatase CheX Fer2_3 PF13085.1 AJZ76667.1 - 0.016 15.0 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF1884 PF08967.5 AJZ76667.1 - 0.063 13.3 0.7 0.3 11.1 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1884) CheB_methylest PF01339.12 AJZ76668.1 - 9.7e-61 204.3 1.4 3.3e-60 202.6 0.7 2.0 3 0 0 3 3 3 1 CheB methylesterase Response_reg PF00072.19 AJZ76668.1 - 5e-16 58.7 0.3 1.2e-15 57.5 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain RNase_H_2 PF13482.1 AJZ76669.1 - 0.066 13.0 0.3 3.2 7.5 0.0 2.2 2 0 0 2 2 2 0 RNase_H superfamily TrmB PF01978.14 AJZ76670.1 - 1.6e-15 56.5 0.0 1.8e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 AJZ76670.1 - 0.00065 19.3 0.0 0.0032 17.1 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family Regulator_TrmB PF11495.3 AJZ76670.1 - 0.0011 17.9 0.1 0.0015 17.5 0.1 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB MarR_2 PF12802.2 AJZ76670.1 - 0.0074 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.2 AJZ76670.1 - 0.0094 15.7 0.0 0.033 13.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Rrf2 PF02082.15 AJZ76670.1 - 0.025 14.6 0.1 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator HTH_24 PF13412.1 AJZ76670.1 - 0.045 13.1 0.9 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MutL_C PF08676.6 AJZ76670.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 MutL C terminal dimerisation domain HTH_IclR PF09339.5 AJZ76670.1 - 0.086 12.4 0.1 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF3919 PF13057.1 AJZ76670.1 - 0.39 10.1 8.1 0.057 12.8 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3919) Peptidase_M10 PF00413.19 AJZ76671.1 - 1.2e-09 38.0 0.1 7.8e-09 35.4 0.1 2.0 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 AJZ76671.1 - 3.4e-05 23.2 0.0 4.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.4 AJZ76671.1 - 0.00092 18.1 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_2 PF13574.1 AJZ76671.1 - 0.0029 17.6 0.1 0.013 15.5 0.1 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 AJZ76671.1 - 0.0047 16.4 0.7 0.013 15.0 0.4 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 AJZ76671.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 AJZ76671.1 - 0.017 15.6 0.1 0.027 14.9 0.1 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Glyco_hydro_108 PF05838.7 AJZ76671.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase 108 Peptidase_M48 PF01435.13 AJZ76671.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_M64 PF09471.5 AJZ76672.1 - 0.11 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 IgA Peptidase M64 AA_kinase PF00696.23 AJZ76673.1 - 3.5e-30 105.3 0.4 4.3e-30 105.0 0.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family Gly-zipper_OmpA PF13436.1 AJZ76674.1 - 0.015 14.9 2.7 0.015 14.9 1.9 1.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF2407_C PF13373.1 AJZ76674.1 - 0.048 13.5 0.0 0.051 13.4 0.0 1.2 1 1 0 1 1 1 0 DUF2407 C-terminal domain ABC_tran PF00005.22 AJZ76675.1 - 1.3e-18 67.6 0.1 1.8e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJZ76675.1 - 0.00011 22.2 0.0 0.00018 21.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 AJZ76675.1 - 0.00019 20.7 0.4 0.00024 20.4 0.3 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 AJZ76675.1 - 0.0029 17.4 0.1 0.13 12.2 0.1 2.7 2 1 1 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 AJZ76675.1 - 0.0037 15.8 0.0 0.0056 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AviRa PF11599.3 AJZ76675.1 - 0.0098 14.9 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa SHOCT PF09851.4 AJZ76676.1 - 0.0028 17.0 0.3 0.0068 15.8 0.2 1.7 1 0 0 1 1 1 1 Short C-terminal domain adh_short_C2 PF13561.1 AJZ76676.1 - 0.026 14.3 0.1 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DivIVA PF05103.8 AJZ76676.1 - 0.23 11.5 2.9 0.47 10.5 2.0 1.5 1 1 0 1 1 1 0 DivIVA protein Gluconate_2-dh3 PF13618.1 AJZ76676.1 - 0.28 11.3 2.0 8.9 6.4 0.3 2.7 2 1 0 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 MethyltransfD12 PF02086.10 AJZ76677.1 - 3.4e-26 92.2 0.2 4.1e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_26 PF13659.1 AJZ76677.1 - 0.087 12.8 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Na_H_Exchanger PF00999.16 AJZ76678.1 - 2.1e-64 217.4 50.5 2.7e-64 217.0 35.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TPR_1 PF00515.23 AJZ76679.1 - 2e-22 77.7 1.2 8.2e-09 34.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 AJZ76679.1 - 1.1e-21 76.1 1.8 2.5e-14 52.6 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 AJZ76679.1 - 2.5e-19 67.5 0.3 2.9e-05 23.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 AJZ76679.1 - 4.9e-15 55.2 1.2 3.5e-09 36.4 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AJZ76679.1 - 3.3e-14 53.0 0.2 2.6e-08 34.2 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AJZ76679.1 - 5.7e-13 47.6 0.8 2.4e-06 26.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 AJZ76679.1 - 3.7e-11 42.3 0.9 0.00062 19.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AJZ76679.1 - 8.7e-11 40.7 0.0 0.0051 16.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 AJZ76679.1 - 1.6e-10 40.6 0.0 0.05 14.2 0.0 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 AJZ76679.1 - 6e-10 39.3 1.8 6.2e-06 26.4 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat A2M_N PF01835.14 AJZ76679.1 - 5.5e-09 36.1 0.5 3.8e-05 23.8 0.0 3.1 2 1 0 2 2 2 2 MG2 domain TPR_10 PF13374.1 AJZ76679.1 - 0.0003 20.5 1.7 0.012 15.5 0.2 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 AJZ76679.1 - 0.00031 21.0 0.5 5.6 7.6 0.0 3.7 3 1 1 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 AJZ76679.1 - 0.0022 18.1 0.1 0.0053 16.8 0.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.3 AJZ76679.1 - 0.0024 16.7 0.2 0.18 10.5 0.0 2.1 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 FAP PF07174.6 AJZ76679.1 - 0.0058 15.9 17.6 0.0095 15.2 12.2 1.3 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) Fis1_TPR_C PF14853.1 AJZ76679.1 - 0.0063 16.3 0.1 2.9 7.8 0.0 2.7 2 1 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.9 AJZ76679.1 - 0.0069 15.6 0.1 0.1 11.7 0.0 2.0 1 1 1 2 2 2 1 Coatomer epsilon subunit TPR_9 PF13371.1 AJZ76679.1 - 0.012 15.5 0.0 0.28 11.0 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.2 AJZ76679.1 - 0.03 14.1 0.1 3.9 7.2 0.0 2.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) MIT PF04212.13 AJZ76679.1 - 0.044 13.6 1.6 8.3 6.3 0.2 3.0 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain PPR PF01535.15 AJZ76679.1 - 0.05 13.5 0.2 7.1 6.8 0.0 3.0 3 0 0 3 3 3 0 PPR repeat TPR_15 PF13429.1 AJZ76679.1 - 0.062 12.3 0.0 1.8 7.5 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat LEA_2 PF03168.8 AJZ76680.1 - 0.0014 18.9 0.1 0.0046 17.3 0.0 1.9 1 1 1 2 2 2 1 Late embryogenesis abundant protein Cpn60_TCP1 PF00118.19 AJZ76681.1 - 1.7e-169 564.5 15.3 2e-169 564.2 10.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pro_isomerase PF00160.16 AJZ76682.1 - 3.9e-44 150.5 0.4 9.7e-44 149.2 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PsbP PF01789.11 AJZ76682.1 - 0.076 12.4 0.0 0.19 11.1 0.0 1.7 1 1 0 1 1 1 0 PsbP Methyltransf_31 PF13847.1 AJZ76683.1 - 1.3e-20 73.5 0.0 1.6e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AJZ76683.1 - 8.1e-17 61.5 0.0 1.3e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJZ76683.1 - 1.9e-15 56.9 0.0 3.5e-15 56.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AJZ76683.1 - 4.8e-15 55.3 0.1 1.4e-14 53.7 0.1 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 AJZ76683.1 - 7.8e-13 48.9 0.0 1.2e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJZ76683.1 - 2.4e-12 47.1 0.1 6e-12 45.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJZ76683.1 - 1e-11 45.0 0.0 2.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AJZ76683.1 - 4.7e-07 29.3 0.2 1.5e-06 27.6 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 AJZ76683.1 - 2.3e-06 27.1 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.7 AJZ76683.1 - 3.1e-05 23.0 0.0 4.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase CheR PF01739.13 AJZ76683.1 - 5.9e-05 22.4 0.5 0.00044 19.6 0.2 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain CMAS PF02353.15 AJZ76683.1 - 0.00016 20.8 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 AJZ76683.1 - 0.00021 21.2 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 AJZ76683.1 - 0.00094 18.1 2.9 0.029 13.2 0.4 2.5 2 1 0 2 2 2 1 mRNA capping enzyme PCMT PF01135.14 AJZ76683.1 - 0.0021 17.6 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 AJZ76683.1 - 0.0036 16.4 0.1 0.006 15.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 AJZ76683.1 - 0.0073 15.0 0.1 0.017 13.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) UPF0020 PF01170.13 AJZ76683.1 - 0.01 15.4 0.2 0.029 13.9 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 GCD14 PF08704.5 AJZ76683.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Flavodoxin_3 PF12641.2 AJZ76683.1 - 0.026 13.9 0.0 0.074 12.4 0.0 1.9 2 1 0 2 2 2 0 Flavodoxin domain FtsJ PF01728.14 AJZ76683.1 - 0.027 14.4 0.0 0.076 12.9 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase RrnaAD PF00398.15 AJZ76683.1 - 0.075 12.0 0.1 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase SieB PF14163.1 AJZ76683.1 - 0.083 12.4 0.8 1.6 8.3 0.2 2.2 2 0 0 2 2 2 0 Superinfection exclusion protein B HK97-gp10_like PF04883.7 AJZ76683.1 - 0.097 13.6 0.3 0.45 11.4 0.0 2.2 2 1 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Methyltransf_2 PF00891.13 AJZ76683.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase Proteasome PF00227.21 AJZ76684.1 - 1.6e-49 167.8 0.4 1.8e-49 167.6 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Fe-ADH_2 PF13685.1 AJZ76685.1 - 2.7e-68 230.0 0.1 3.5e-68 229.5 0.1 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 AJZ76685.1 - 2.5e-21 75.7 0.1 3.8e-21 75.1 0.0 1.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 AJZ76685.1 - 1.4e-06 27.4 0.1 8.9e-06 24.8 0.1 2.2 1 1 0 1 1 1 1 3-dehydroquinate synthase Collagen_bind_2 PF12904.2 AJZ76685.1 - 0.00093 18.9 0.1 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Putative collagen-binding domain of a collagenase APS_kinase PF01583.15 AJZ76686.1 - 6.5e-45 152.6 0.0 7.6e-45 152.3 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 AJZ76686.1 - 2.8e-06 27.2 0.0 5.2e-06 26.3 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 AJZ76686.1 - 2.6e-05 24.5 0.2 0.00014 22.1 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 AJZ76686.1 - 0.00021 22.0 0.0 0.00036 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 AJZ76686.1 - 0.001 18.7 0.0 0.014 14.9 0.0 2.2 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 AJZ76686.1 - 0.0022 17.2 0.1 0.021 14.0 0.0 2.0 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 AJZ76686.1 - 0.0089 15.1 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Mlp PF03304.8 AJZ76686.1 - 0.028 14.4 0.4 0.06 13.3 0.1 1.8 1 1 1 2 2 2 0 Mlp lipoprotein family AAA_28 PF13521.1 AJZ76686.1 - 0.034 14.0 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AJZ76686.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HTH_45 PF14947.1 AJZ76688.1 - 5.6e-09 35.6 0.1 6.7e-09 35.4 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_27 PF13463.1 AJZ76688.1 - 4.7e-06 26.8 0.1 6.2e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.2 AJZ76688.1 - 3e-05 23.5 0.0 4.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 MarR family DUF4364 PF14277.1 AJZ76688.1 - 0.002 17.7 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) TrmB PF01978.14 AJZ76688.1 - 0.049 13.3 0.1 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.4 AJZ76688.1 - 0.074 12.9 0.0 0.36 10.7 0.0 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) S10_plectin PF03501.10 AJZ76688.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Plectin/S10 domain DUF3116 PF11313.3 AJZ76688.1 - 0.11 12.1 0.1 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) HhH-GPD PF00730.20 AJZ76689.1 - 9.5e-24 83.7 0.1 1.4e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AJZ76689.1 - 5.9e-09 35.1 0.0 2.8e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF2400 PF09674.5 AJZ76689.1 - 0.0015 18.2 0.0 0.0045 16.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2400) HHH_5 PF14520.1 AJZ76689.1 - 0.021 14.9 0.0 0.15 12.2 0.0 2.1 1 1 0 1 1 1 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 AJZ76689.1 - 0.42 10.8 3.2 0.81 9.9 2.2 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III PhnA_Zn_Ribbon PF08274.7 AJZ76690.1 - 6.4e-05 22.6 8.4 0.0016 18.1 1.9 2.1 1 1 1 2 2 2 2 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.1 AJZ76690.1 - 0.00075 19.1 3.7 0.014 15.0 2.6 2.1 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AJZ76690.1 - 0.001 18.5 3.6 0.0077 15.7 2.5 2.0 1 1 0 1 1 1 1 zinc-ribbon domain CpXC PF14353.1 AJZ76690.1 - 0.0016 18.3 3.2 0.0048 16.8 0.1 2.0 1 1 1 2 2 2 1 CpXC protein IBR PF01485.16 AJZ76690.1 - 0.0036 17.1 1.2 0.0055 16.5 0.8 1.3 1 0 0 1 1 1 1 IBR domain OrfB_Zn_ribbon PF07282.6 AJZ76690.1 - 0.0057 16.2 0.6 0.0091 15.6 0.4 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain UPF0547 PF10571.4 AJZ76690.1 - 0.0062 16.2 6.5 0.041 13.5 4.5 1.9 1 1 0 1 1 1 1 Uncharacterised protein family UPF0547 Zn_Tnp_IS1 PF03811.8 AJZ76690.1 - 0.0077 15.6 1.3 2.2 7.8 0.1 2.1 2 0 0 2 2 2 2 InsA N-terminal domain Ribosomal_S27e PF01667.12 AJZ76690.1 - 0.0089 15.5 2.3 0.047 13.2 1.5 1.9 1 1 1 2 2 2 1 Ribosomal protein S27 RIG-I_C-RD PF11648.3 AJZ76690.1 - 0.014 15.2 0.1 0.015 15.1 0.1 1.0 1 0 0 1 1 1 0 C-terminal domain of RIG-I zf-DNL PF05180.7 AJZ76690.1 - 0.014 15.0 1.2 0.12 12.1 0.6 2.0 1 1 1 2 2 2 0 DNL zinc finger zf-ribbon_3 PF13248.1 AJZ76690.1 - 0.016 14.4 4.4 0.14 11.3 3.4 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zf-ISL3 PF14690.1 AJZ76690.1 - 0.022 14.8 0.3 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HypA PF01155.14 AJZ76690.1 - 0.031 13.9 0.3 0.032 13.9 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF329 PF03884.9 AJZ76690.1 - 0.032 13.7 3.4 0.68 9.5 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF329) Prok-RING_1 PF14446.1 AJZ76690.1 - 0.042 13.5 1.8 0.055 13.2 1.2 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2387 PF09526.5 AJZ76690.1 - 0.051 13.5 2.1 0.086 12.7 1.5 1.4 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) DZR PF12773.2 AJZ76690.1 - 0.055 13.2 1.9 0.11 12.3 1.3 1.4 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_4 PF13894.1 AJZ76690.1 - 0.071 13.4 0.4 4.1 7.9 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AJZ76690.1 - 0.078 13.3 3.9 3.7 8.0 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 AJZ76690.1 - 0.11 12.7 0.3 0.11 12.7 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DNA_RNApol_7kD PF03604.8 AJZ76690.1 - 0.11 11.9 1.0 0.2 11.1 0.7 1.3 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-C4_Topoisom PF01396.14 AJZ76690.1 - 0.17 11.3 2.7 6 6.4 0.2 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-RING_3 PF14369.1 AJZ76690.1 - 0.19 11.7 5.1 3.7 7.6 3.9 2.1 1 1 1 2 2 2 0 zinc-finger zf-C2H2 PF00096.21 AJZ76690.1 - 0.21 12.0 1.2 16 6.0 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.7 AJZ76690.1 - 0.22 10.8 3.1 8 5.8 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Ogr_Delta PF04606.7 AJZ76690.1 - 0.23 11.1 2.1 4.6 6.9 0.1 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zinc-ribbons_6 PF07191.7 AJZ76690.1 - 0.24 11.2 2.7 0.37 10.6 1.9 1.4 1 1 0 1 1 1 0 zinc-ribbons zf-ZPR1 PF03367.8 AJZ76690.1 - 0.33 10.0 2.1 3.5 6.7 1.4 2.0 1 1 0 1 1 1 0 ZPR1 zinc-finger domain zf-RING_4 PF14570.1 AJZ76690.1 - 0.4 10.3 5.3 3.5 7.3 3.7 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Mu-like_Com PF10122.4 AJZ76690.1 - 0.47 9.5 2.0 1.1 8.4 1.4 1.6 1 1 0 1 1 1 0 Mu-like prophage protein Com zf-Di19 PF05605.7 AJZ76690.1 - 1 9.5 5.2 2.8 8.1 0.6 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 AJZ76690.1 - 1.1 9.2 6.7 9.5 6.2 0.8 2.1 1 1 1 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 AJZ76690.1 - 1.6 8.5 5.0 6.5 6.6 0.4 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 AJZ76690.1 - 4.2 6.9 7.5 3.6 7.2 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Pro_isomerase PF00160.16 AJZ76691.1 - 5.5e-49 166.3 0.1 6.3e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CobA_CobO_BtuR PF02572.10 AJZ76692.1 - 5.6e-64 214.8 0.7 6.2e-64 214.7 0.5 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP IstB_IS21 PF01695.12 AJZ76692.1 - 0.0015 17.9 2.8 0.36 10.2 0.1 2.1 1 1 1 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.1 AJZ76692.1 - 0.0017 18.4 2.4 0.0052 16.9 1.7 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AJZ76692.1 - 0.0027 17.6 1.2 0.0076 16.1 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 AJZ76692.1 - 0.0052 16.9 2.9 0.012 15.7 2.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Response_reg PF00072.19 AJZ76692.1 - 0.0095 15.9 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Arch_ATPase PF01637.13 AJZ76692.1 - 0.016 14.9 1.1 0.023 14.4 0.7 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 AJZ76692.1 - 0.085 12.6 0.1 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Part of AAA domain SRP54 PF00448.17 AJZ76692.1 - 2 7.8 6.1 4.9 6.5 0.5 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CbiG_N PF11760.3 AJZ76693.1 - 2.1e-32 110.6 0.1 3.5e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis G N-terminal CbiG_C PF01890.11 AJZ76693.1 - 4.5e-31 107.6 0.0 1e-30 106.4 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus CbiG_mid PF11761.3 AJZ76693.1 - 8e-14 51.6 0.0 1.6e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Cobalamin biosynthesis central region UME PF08064.8 AJZ76693.1 - 0.029 14.2 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 UME (NUC010) domain QH-AmDH_gamma PF08992.6 AJZ76693.1 - 0.033 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit LSM PF01423.17 AJZ76694.1 - 4e-18 64.7 1.7 4.6e-18 64.5 1.2 1.1 1 0 0 1 1 1 1 LSM domain Pox_A31 PF05771.6 AJZ76694.1 - 0.026 14.3 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A31 protein CutA1 PF03091.10 AJZ76695.1 - 4.3e-30 103.3 0.9 4.7e-30 103.2 0.6 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein PAS_6 PF08348.6 AJZ76695.1 - 0.016 14.7 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 YheO-like PAS domain Radical_SAM PF04055.16 AJZ76696.1 - 2.6e-16 60.2 0.1 2.6e-16 60.2 0.1 2.8 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_14 PF13394.1 AJZ76696.1 - 2.1e-07 30.9 0.0 2.1e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AJZ76696.1 - 3.1e-07 30.5 0.0 7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain UDPG_MGDP_dh_N PF03721.9 AJZ76697.1 - 2.2e-37 128.2 0.0 4.7e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 AJZ76697.1 - 5.9e-24 84.2 0.1 1.4e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 AJZ76697.1 - 2.4e-21 75.7 0.1 4.9e-21 74.7 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 2-Hacid_dh_C PF02826.14 AJZ76697.1 - 2.5e-05 23.5 0.1 0.78 8.8 0.0 3.4 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 AJZ76697.1 - 0.00019 21.2 0.0 0.00099 18.9 0.0 2.2 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 AJZ76697.1 - 0.004 16.8 0.0 0.37 10.4 0.0 2.7 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 AJZ76697.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 AJZ76697.1 - 0.019 15.0 0.3 0.037 14.0 0.2 1.4 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase TrkA_N PF02254.13 AJZ76697.1 - 0.048 13.6 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 AJZ76697.1 - 0.054 13.9 1.3 1.1 9.6 0.0 3.0 4 0 0 4 4 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 AJZ76697.1 - 0.058 13.8 0.6 8.7 6.8 0.1 3.6 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 AJZ76697.1 - 0.081 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TEX19 PF15553.1 AJZ76698.1 - 0.036 13.9 0.0 0.051 13.4 0.0 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 Methyltransf_31 PF13847.1 AJZ76699.1 - 1.5e-18 66.8 1.0 4.5e-18 65.2 0.7 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AJZ76699.1 - 3.5e-14 53.0 0.0 6.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJZ76699.1 - 8e-12 45.1 0.1 1.1e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJZ76699.1 - 1.2e-11 44.8 0.0 3.3e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJZ76699.1 - 3.8e-11 43.5 0.0 6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJZ76699.1 - 1.9e-10 41.0 0.0 4.7e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 AJZ76699.1 - 9.8e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 AJZ76699.1 - 0.0003 20.8 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AJZ76699.1 - 0.00042 19.7 0.0 0.00066 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 AJZ76699.1 - 0.0015 17.6 0.0 0.0023 16.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_4 PF02390.12 AJZ76699.1 - 0.0068 15.4 0.1 0.038 13.0 0.0 1.9 1 1 0 2 2 2 1 Putative methyltransferase RrnaAD PF00398.15 AJZ76699.1 - 0.007 15.4 0.0 0.0097 14.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Sulfotransfer_1 PF00685.22 AJZ76700.1 - 4.9e-28 98.1 1.3 6.3e-28 97.7 0.9 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 AJZ76700.1 - 4.7e-09 37.3 0.0 6.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.9 AJZ76700.1 - 0.0034 17.1 0.8 0.0082 15.8 0.5 1.7 1 1 0 1 1 1 1 Sulfotransferase family Glycos_transf_2 PF00535.21 AJZ76701.1 - 3.5e-28 98.3 0.1 5.8e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AJZ76701.1 - 5.6e-21 75.3 0.0 7e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 AJZ76701.1 - 3.7e-10 39.8 0.0 4.8e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.4 AJZ76701.1 - 1.9e-06 27.1 1.0 3.6e-06 26.2 0.7 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AJZ76701.1 - 0.00023 20.4 0.0 0.00036 19.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_5 PF13712.1 AJZ76701.1 - 0.034 13.3 0.3 0.65 9.1 0.0 2.6 2 1 1 3 3 3 0 Glycosyltransferase like family Glyco_tranf_2_4 PF13704.1 AJZ76701.1 - 0.039 14.2 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 CmcI PF04989.7 AJZ76702.1 - 1.4e-86 289.0 0.0 1.8e-86 288.6 0.0 1.1 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_24 PF13578.1 AJZ76702.1 - 1.3e-10 42.0 0.0 2.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 AJZ76702.1 - 0.093 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Alg14 PF08660.6 AJZ76702.1 - 0.099 12.6 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like CS PF04969.11 AJZ76702.1 - 0.099 13.2 0.6 0.4 11.2 0.1 2.2 2 0 0 2 2 2 0 CS domain Epimerase PF01370.16 AJZ76703.1 - 1.1e-29 103.5 0.0 1.7e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AJZ76703.1 - 1e-13 50.8 1.4 2.7e-13 49.4 1.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 AJZ76703.1 - 4.1e-08 32.4 0.0 6.2e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 AJZ76703.1 - 6.4e-08 31.6 0.0 8.5e-08 31.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AJZ76703.1 - 6.6e-07 28.5 1.5 7.1e-07 28.4 0.1 1.7 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 AJZ76703.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GFO_IDH_MocA PF01408.17 AJZ76704.1 - 4.8e-05 23.8 0.0 0.00015 22.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold PIG-L PF02585.12 AJZ76705.1 - 7.2e-21 75.0 0.0 9.8e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glyco_trans_4_2 PF13477.1 AJZ76705.1 - 0.0076 16.0 0.3 0.021 14.6 0.1 1.8 1 1 1 2 2 2 1 Glycosyl transferase 4-like DUF2490 PF10677.4 AJZ76705.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2490) DUF3626 PF12294.3 AJZ76705.1 - 0.047 12.7 0.1 0.061 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) MeMO_Hyd_G PF02964.11 AJZ76705.1 - 0.058 13.3 0.1 13 5.7 0.0 3.0 1 1 1 3 3 3 0 Methane monooxygenase, hydrolase gamma chain DegT_DnrJ_EryC1 PF01041.12 AJZ76706.1 - 4.1e-97 325.4 0.0 4.6e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 AJZ76706.1 - 2.7e-06 26.7 0.0 5.7e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AJZ76706.1 - 0.00082 17.7 0.0 0.0012 17.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Polyketide_cyc2 PF10604.4 AJZ76708.1 - 1.2e-10 41.6 0.1 1.5e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AJZ76708.1 - 1.1e-07 31.8 0.1 2e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 AJZ76708.1 - 3e-07 30.5 0.1 4.1e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein FMN_red PF03358.10 AJZ76709.1 - 3.3e-15 55.8 0.0 4.8e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Rieske PF00355.21 AJZ76709.1 - 1.6e-11 43.6 0.0 3.1e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Flavodoxin_2 PF02525.12 AJZ76709.1 - 4.2e-05 23.1 0.0 5.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Rieske_2 PF13806.1 AJZ76709.1 - 0.0082 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain HTH_5 PF01022.15 AJZ76710.1 - 2.7e-07 30.1 0.0 3.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.14 AJZ76710.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 AJZ76710.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain B-block_TFIIIC PF04182.7 AJZ76710.1 - 0.057 13.2 0.4 0.24 11.2 0.1 2.0 2 1 1 3 3 3 0 B-block binding subunit of TFIIIC DUF2250 PF10007.4 AJZ76710.1 - 0.083 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Copper-bind PF00127.15 AJZ76711.1 - 2.1e-09 37.5 0.0 2.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJZ76711.1 - 5.2e-09 35.9 0.1 6.7e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 Cupredoxin-like domain ABC_tran PF00005.22 AJZ76712.1 - 9.3e-30 103.7 0.0 1.3e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJZ76712.1 - 1.1e-13 51.8 0.0 1.5e-07 31.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 AJZ76712.1 - 3.1e-09 36.3 0.0 1.3e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 AJZ76712.1 - 8.9e-07 28.2 0.4 0.0025 16.9 0.2 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 AJZ76712.1 - 2.3e-05 24.5 0.0 7.3e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AJZ76712.1 - 0.0006 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 AJZ76712.1 - 0.002 17.6 0.4 1 8.6 0.0 2.1 1 1 1 2 2 2 2 AAA-like domain AAA_23 PF13476.1 AJZ76712.1 - 0.0037 17.6 0.0 0.012 15.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AJZ76712.1 - 0.0038 16.7 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.10 AJZ76712.1 - 0.0049 15.6 0.0 0.0071 15.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 AJZ76712.1 - 0.0092 15.9 0.2 0.044 13.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 AJZ76712.1 - 0.022 14.9 0.1 0.25 11.5 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AJZ76712.1 - 0.037 13.8 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AJZ76712.1 - 0.046 14.5 0.2 0.12 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AJZ76712.1 - 0.048 13.3 0.9 0.41 10.2 0.7 2.2 1 1 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 AJZ76712.1 - 0.055 13.7 0.1 0.14 12.5 0.0 1.9 2 1 0 2 2 1 0 AAA domain AAA_19 PF13245.1 AJZ76712.1 - 0.072 12.8 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain P22_CoatProtein PF11651.3 AJZ76712.1 - 0.082 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 UPF0079 PF02367.12 AJZ76712.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 AJZ76712.1 - 0.1 12.7 0.1 0.91 9.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 AJZ76712.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 AJZ76712.1 - 0.12 11.8 0.5 0.28 10.6 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 AJZ76712.1 - 0.12 11.0 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit BPD_transp_1 PF00528.17 AJZ76713.1 - 3.3e-17 62.6 14.8 3.3e-17 62.6 10.2 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3413 PF11893.3 AJZ76713.1 - 3.6 6.3 13.2 1 8.1 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3413) CitMHS PF03600.11 AJZ76714.1 - 3.1e-59 200.3 33.1 3.1e-59 200.3 22.9 2.0 1 1 1 2 2 2 2 Citrate transporter ArsB PF02040.10 AJZ76714.1 - 3.1e-25 89.0 37.3 4.6e-25 88.4 25.8 1.2 1 0 0 1 1 1 1 Arsenical pump membrane protein DctM PF06808.7 AJZ76714.1 - 0.22 10.0 36.8 0.017 13.6 16.2 2.9 3 0 0 3 3 3 0 DctM-like transporters Sulfate_transp PF00916.15 AJZ76715.1 - 0.042 12.8 2.5 0.06 12.3 1.8 1.3 1 1 0 1 1 1 0 Sulfate transporter family Ammonium_transp PF00909.16 AJZ76715.1 - 0.059 11.8 1.0 0.07 11.5 0.7 1.0 1 0 0 1 1 1 0 Ammonium Transporter Family Bestrophin PF01062.16 AJZ76715.1 - 0.063 12.2 0.1 0.063 12.2 0.1 1.4 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel LMWPc PF01451.16 AJZ76716.1 - 2.1e-18 66.9 0.0 2.5e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Urease_beta PF00699.15 AJZ76717.1 - 2.1e-42 143.0 0.0 2.4e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 Urease beta subunit PapD_N PF00345.15 AJZ76717.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.3 1 1 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain GTP_EFTU PF00009.22 AJZ76718.1 - 5.4e-32 110.7 0.4 1.4e-31 109.3 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 AJZ76718.1 - 6.4e-24 83.9 2.2 2.1e-23 82.2 0.5 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.1 AJZ76718.1 - 9.5e-12 44.3 2.4 1.2e-11 44.0 0.2 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 AJZ76718.1 - 7.3e-10 38.8 1.4 1.9e-08 34.2 0.0 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AJZ76718.1 - 3.9e-07 30.0 0.3 1.6e-06 28.0 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 AJZ76718.1 - 1.3e-05 24.9 0.0 6.6e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 AJZ76718.1 - 5.2e-05 23.7 0.1 0.00022 21.7 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 AJZ76718.1 - 0.00063 19.6 0.9 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Dynamin family Ras PF00071.17 AJZ76718.1 - 0.016 14.6 0.2 0.071 12.4 0.0 2.2 2 0 0 2 2 2 0 Ras family Tmemb_185A PF10269.4 AJZ76719.1 - 0.0067 16.0 2.0 0.0073 15.9 1.4 1.0 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF4212 PF13937.1 AJZ76719.1 - 0.026 14.4 2.0 0.028 14.4 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) DUF4577 PF15145.1 AJZ76719.1 - 0.09 12.6 0.8 0.097 12.5 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Vpu PF00558.14 AJZ76719.1 - 0.18 11.4 1.7 0.26 10.8 1.2 1.3 1 0 0 1 1 1 0 Vpu protein NAD_binding_1 PF00175.16 AJZ76720.1 - 9e-13 48.7 0.0 2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AJZ76720.1 - 6.1e-12 45.5 0.0 8.9e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AJZ76720.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Fer2_3 PF13085.1 AJZ76721.1 - 1.8e-31 108.1 0.6 3.5e-31 107.2 0.0 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.1 AJZ76721.1 - 4.1e-12 45.9 4.6 8.8e-12 44.8 1.5 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 AJZ76721.1 - 1.5e-10 41.3 4.6 3.2e-08 33.8 0.1 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 AJZ76721.1 - 2.3e-09 37.4 11.9 1e-07 32.1 2.0 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 AJZ76721.1 - 1.8e-08 34.0 2.3 1.8e-08 34.0 1.6 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AJZ76721.1 - 2.3e-08 34.1 2.1 2.3e-08 34.1 1.5 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 AJZ76721.1 - 1.9e-06 28.1 10.3 3.4e-06 27.3 4.6 2.8 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 AJZ76721.1 - 4.4e-05 23.1 0.2 4.4e-05 23.1 0.1 1.8 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.22 AJZ76721.1 - 0.0001 21.7 1.6 0.0001 21.7 1.1 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.2 AJZ76721.1 - 0.0002 21.0 13.6 0.00025 20.7 1.4 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.1 AJZ76721.1 - 0.0011 19.6 4.5 0.0011 19.6 3.1 2.5 2 2 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_6 PF12837.2 AJZ76721.1 - 0.0058 16.4 2.1 0.0058 16.4 1.4 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_4 PF12800.2 AJZ76721.1 - 0.074 13.4 1.9 0.074 13.4 1.3 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.2 AJZ76721.1 - 0.15 12.7 0.9 0.15 12.7 0.6 3.1 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_21 PF14697.1 AJZ76721.1 - 0.2 11.5 12.6 0.29 11.0 5.6 3.0 3 1 0 3 3 3 0 4Fe-4S dicluster domain Lyase_1 PF00206.15 AJZ76722.1 - 5.2e-55 186.8 0.1 1e-54 185.8 0.1 1.5 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 AJZ76722.1 - 1.4e-16 60.3 1.0 4e-16 58.8 0.0 2.4 3 0 0 3 3 3 1 Argininosuccinate lyase C-terminal AAA PF00004.24 AJZ76723.1 - 2.3e-14 53.7 0.1 5.8e-14 52.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AJZ76723.1 - 2e-09 36.8 0.0 6.5e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AJZ76723.1 - 9.9e-08 32.8 0.1 3.5e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AJZ76723.1 - 1.1e-06 28.5 0.0 3.1e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 AJZ76723.1 - 3.5e-06 25.9 0.4 0.0042 15.8 0.0 3.0 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AJZ76723.1 - 7.2e-06 26.1 0.1 0.00044 20.3 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 AJZ76723.1 - 2.2e-05 24.7 0.0 6.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 AJZ76723.1 - 2.2e-05 23.3 0.0 4.8e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 AJZ76723.1 - 6.9e-05 22.8 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.10 AJZ76723.1 - 0.00012 21.8 0.0 0.00049 19.8 0.0 2.0 1 1 1 2 2 2 1 NTPase AAA_5 PF07728.9 AJZ76723.1 - 0.00033 20.3 0.1 0.001 18.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AJZ76723.1 - 0.00078 19.4 0.0 0.0026 17.7 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.7 AJZ76723.1 - 0.0011 18.6 0.0 0.063 12.9 0.0 2.6 3 0 0 3 3 3 1 NACHT domain AAA_33 PF13671.1 AJZ76723.1 - 0.0012 18.7 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AJZ76723.1 - 0.0026 16.8 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 AJZ76723.1 - 0.0053 16.1 0.0 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 AJZ76723.1 - 0.009 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 AJZ76723.1 - 0.012 14.4 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.16 AJZ76723.1 - 0.013 14.6 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 AJZ76723.1 - 0.015 15.0 0.0 0.037 13.7 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 AJZ76723.1 - 0.024 14.1 0.1 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 AJZ76723.1 - 0.028 14.4 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 AJZ76723.1 - 0.033 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AJZ76723.1 - 0.044 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AJZ76723.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SRCR_2 PF15494.1 AJZ76724.1 - 0.095 12.9 2.8 0.1 12.8 0.1 2.1 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain DUF2197 PF09963.4 AJZ76724.1 - 2.1 8.3 0.0 2.1 8.3 0.0 3.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Carboxyl_trans PF01039.17 AJZ76725.1 - 3.3e-183 609.5 0.3 3.8e-183 609.3 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 AJZ76725.1 - 2.4e-07 30.1 0.0 6.2e-07 28.8 0.0 1.6 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) Oxidored_q1 PF00361.15 AJZ76726.1 - 2.1e-57 194.4 22.9 7.2e-53 179.5 14.4 4.0 4 2 1 5 5 5 2 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 AJZ76726.1 - 7.9e-10 38.1 1.5 7.9e-10 38.1 1.0 2.8 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q1_C PF01010.14 AJZ76726.1 - 3.4e-05 23.4 1.0 0.021 14.3 0.3 2.4 1 1 1 2 2 2 2 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus DUF2839 PF10999.3 AJZ76726.1 - 0.084 12.9 2.3 1.4 9.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) Peptidase_M10 PF00413.19 AJZ76727.1 - 5.3e-09 35.9 0.0 1.1e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 AJZ76727.1 - 8.1e-05 22.0 0.5 0.00019 20.8 0.1 1.6 1 1 0 2 2 2 1 Dual-action HEIGH metallo-peptidase DUF2268 PF10026.4 AJZ76727.1 - 0.0026 17.1 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 1 Predicted Zn-dependent protease (DUF2268) Reprolysin_5 PF13688.1 AJZ76727.1 - 0.0079 16.1 0.1 0.01 15.7 0.1 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.4 AJZ76727.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.1 AJZ76727.1 - 0.022 15.3 0.3 0.03 14.8 0.2 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 AJZ76727.1 - 0.025 14.6 0.2 0.032 14.2 0.1 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 AJZ76727.1 - 0.036 13.5 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.3 AJZ76727.1 - 0.062 12.8 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) HTH_45 PF14947.1 AJZ76728.1 - 1.6e-13 50.2 0.5 2.6e-13 49.5 0.4 1.3 1 1 0 1 1 1 1 Winged helix-turn-helix Baculo_LEF5 PF04838.7 AJZ76728.1 - 0.047 13.4 0.4 0.21 11.3 0.1 1.8 1 1 1 2 2 2 0 Baculoviridae late expression factor 5 DUF2653 PF10850.3 AJZ76728.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) Met_10 PF02475.11 AJZ76730.1 - 7.2e-63 211.8 0.0 8.8e-63 211.5 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 AJZ76730.1 - 1.7e-05 24.1 0.1 2.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 AJZ76730.1 - 6.6e-05 23.4 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AJZ76730.1 - 0.00075 19.5 0.0 0.0025 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 AJZ76730.1 - 0.0012 18.4 0.1 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRM PF02005.11 AJZ76730.1 - 0.0026 16.7 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.9 AJZ76730.1 - 0.0075 15.6 0.0 0.033 13.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 AJZ76730.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltrans_SAM PF10672.4 AJZ76730.1 - 0.02 13.7 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Methyltransf_16 PF10294.4 AJZ76730.1 - 0.056 12.8 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Cons_hypoth95 PF03602.10 AJZ76730.1 - 0.092 12.1 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 MscL PF01741.13 AJZ76731.1 - 3.9e-19 69.0 5.0 4.2e-19 68.9 3.5 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Glycoprotein_B PF00606.13 AJZ76731.1 - 0.027 12.5 0.2 0.039 11.9 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B STE2 PF02116.10 AJZ76731.1 - 0.036 13.0 0.2 0.052 12.5 0.2 1.2 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR FtsX PF02687.16 AJZ76731.1 - 0.07 12.9 3.4 0.095 12.4 2.3 1.1 1 0 0 1 1 1 0 FtsX-like permease family Colicin_V PF02674.11 AJZ76731.1 - 0.29 10.9 5.9 0.67 9.8 4.1 1.6 1 1 0 1 1 1 0 Colicin V production protein Transketolase_N PF00456.16 AJZ76732.1 - 3.3e-59 200.3 0.5 1.5e-57 194.9 0.3 2.3 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Ribul_P_3_epim PF00834.14 AJZ76732.1 - 4.7e-52 176.0 0.1 7.1e-52 175.4 0.1 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family E1_dh PF00676.15 AJZ76732.1 - 0.00012 20.8 0.0 0.00022 20.0 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 AJZ76732.1 - 0.00034 19.6 0.0 0.026 13.4 0.0 2.8 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 AJZ76732.1 - 0.001 18.6 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.5 AJZ76732.1 - 0.002 16.7 1.3 0.068 11.7 0.0 2.9 2 1 0 3 3 3 1 XFP N-terminal domain Transket_pyr PF02779.19 AJZ76733.1 - 3.1e-33 114.7 0.0 4e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AJZ76733.1 - 2.1e-28 98.7 0.0 3.7e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Lactamase_B PF00753.22 AJZ76734.1 - 9.6e-27 93.8 0.2 1.4e-26 93.3 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Rhodanese PF00581.15 AJZ76734.1 - 1.6e-15 57.3 0.0 5.4e-15 55.7 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Lactamase_B_3 PF13483.1 AJZ76734.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 AJZ76734.1 - 0.0059 16.1 0.1 0.012 15.1 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DAO PF01266.19 AJZ76735.1 - 0.002 17.1 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AJZ76735.1 - 0.014 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 AJZ76735.1 - 0.071 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AJZ76735.1 - 0.087 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain tRNA-synt_2d PF01409.15 AJZ76736.1 - 5e-89 297.7 0.0 8.6e-89 296.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 AJZ76736.1 - 4.8e-06 25.5 0.1 0.00049 18.9 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 AJZ76736.1 - 0.0016 18.0 0.0 0.0037 16.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HTH_11 PF08279.7 AJZ76736.1 - 0.035 13.7 0.6 0.36 10.4 0.4 2.3 2 0 0 2 2 2 0 HTH domain HTH_9 PF08221.6 AJZ76736.1 - 0.065 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain AsnC_trans_reg PF01037.16 AJZ76737.1 - 1.5e-12 46.9 0.0 1.8e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 AsnC family GYD PF08734.6 AJZ76737.1 - 0.034 13.8 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 GYD domain PTPS PF01242.14 AJZ76739.1 - 9e-20 70.5 0.1 2.2e-19 69.3 0.0 1.5 2 0 0 2 2 2 1 6-pyruvoyl tetrahydropterin synthase TatD_DNase PF01026.16 AJZ76740.1 - 2.2e-37 128.6 0.0 2.4e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Adenylsucc_synt PF00709.16 AJZ76741.1 - 6.8e-86 288.5 1.2 7.8e-39 133.5 0.0 3.0 1 1 2 3 3 3 3 Adenylosuccinate synthetase eIF-5_eIF-2B PF01873.12 AJZ76742.1 - 9.8e-31 106.0 0.0 1.2e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 AJZ76742.1 - 0.00033 19.8 1.4 0.00059 19.1 1.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Elf1 PF05129.8 AJZ76742.1 - 0.017 14.8 0.2 0.033 13.8 0.2 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 AJZ76742.1 - 0.018 15.3 0.7 0.031 14.5 0.5 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-TFIIB PF13453.1 AJZ76742.1 - 0.033 13.3 2.0 0.033 13.3 1.4 1.7 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF2387 PF09526.5 AJZ76742.1 - 0.069 13.0 0.4 0.15 12.0 0.3 1.5 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.5 AJZ76742.1 - 0.073 13.0 1.9 1.9 8.5 0.1 2.3 1 1 1 2 2 2 0 Zinc ribbon domain DZR PF12773.2 AJZ76742.1 - 0.25 11.2 1.6 0.56 10.0 1.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon TFIIS_C PF01096.13 AJZ76742.1 - 1.9 8.2 4.0 57 3.4 2.8 2.2 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) RIO1 PF01163.17 AJZ76743.1 - 4.2e-53 179.5 0.0 6.7e-53 178.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 AJZ76743.1 - 0.00028 20.7 0.0 0.039 13.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family MFS_Mycoplasma PF07672.8 AJZ76743.1 - 0.036 13.2 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Mycoplasma MFS transporter Methyltransf_25 PF13649.1 AJZ76743.1 - 0.085 13.2 0.0 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain HATPase_c PF02518.21 AJZ76744.1 - 3.2e-22 78.3 0.1 5.1e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 AJZ76744.1 - 7.4e-11 41.6 0.4 1.5e-10 40.6 0.3 1.5 1 0 0 1 1 1 1 GHKL domain HisKA PF00512.20 AJZ76744.1 - 3.2e-10 39.8 0.6 9.5e-10 38.3 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 AJZ76744.1 - 3.8e-05 23.3 0.1 8.2e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cas_Cas4 PF01930.12 AJZ76744.1 - 0.025 14.4 0.0 0.077 12.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF83 HATPase_c_2 PF13581.1 AJZ76744.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain STN PF07660.9 AJZ76744.1 - 0.054 13.0 0.1 0.24 11.0 0.1 2.1 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain zf-met PF12874.2 AJZ76745.1 - 0.082 13.1 0.5 0.18 12.0 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type RNA_pol_Rpc34 PF05158.7 AJZ76747.1 - 5.7e-07 29.0 0.0 6.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR PF01047.17 AJZ76747.1 - 1e-05 25.1 0.1 1.4e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 MarR family B-block_TFIIIC PF04182.7 AJZ76747.1 - 0.064 13.1 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC MFS_1 PF07690.11 AJZ76748.1 - 2.5e-44 151.4 78.6 8.4e-42 143.1 30.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AJZ76748.1 - 9.1e-09 34.3 11.9 9.1e-09 34.3 8.3 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 AJZ76748.1 - 0.0038 15.6 5.9 0.0038 15.6 4.1 4.1 1 1 0 2 2 2 1 MFS/sugar transport protein DUF2371 PF10177.4 AJZ76748.1 - 1.7 8.5 8.4 3.8 7.3 0.2 2.9 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) Thioredoxin_4 PF13462.1 AJZ76749.1 - 8.7e-42 142.8 0.0 1.1e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 AJZ76749.1 - 3.2e-17 62.7 0.0 3.7e-16 59.2 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 AJZ76749.1 - 1.7e-10 41.0 0.0 5.8e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AJZ76749.1 - 4.8e-05 23.4 0.1 0.002 18.2 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_5 PF13743.1 AJZ76749.1 - 0.0016 18.0 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.15 AJZ76749.1 - 0.0032 17.1 0.0 0.097 12.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 AJZ76749.1 - 0.041 13.6 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain DUF4307 PF14155.1 AJZ76750.1 - 0.18 11.5 0.6 0.32 10.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Proteasome PF00227.21 AJZ76751.1 - 1.2e-52 177.9 0.4 1.6e-52 177.5 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AJZ76751.1 - 2.2e-11 42.8 2.8 3.1e-11 42.3 0.1 2.4 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Synuclein PF01387.12 AJZ76751.1 - 0.026 14.4 1.5 0.029 14.2 0.1 1.8 2 0 0 2 2 2 0 Synuclein HTH_5 PF01022.15 AJZ76752.1 - 2.4e-11 43.0 0.0 4.6e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 AJZ76752.1 - 2.7e-06 26.6 0.5 4.9e-06 25.8 0.4 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_45 PF14947.1 AJZ76752.1 - 4.3e-05 23.2 0.9 6.2e-05 22.7 0.6 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_20 PF12840.2 AJZ76752.1 - 4.6e-05 23.1 0.0 9.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 AJZ76752.1 - 0.00012 21.7 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 AJZ76752.1 - 0.0064 16.3 0.2 0.01 15.6 0.1 1.5 1 1 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_12 PF08461.5 AJZ76752.1 - 0.011 15.4 0.1 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain HTH_29 PF13551.1 AJZ76752.1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix TFIIE_alpha PF02002.12 AJZ76752.1 - 0.013 14.9 0.2 0.017 14.6 0.2 1.1 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_34 PF13601.1 AJZ76752.1 - 0.015 15.3 1.0 0.046 13.7 0.2 1.9 1 1 1 2 2 2 0 Winged helix DNA-binding domain MarR PF01047.17 AJZ76752.1 - 0.015 14.9 0.1 0.03 14.0 0.1 1.5 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.2 AJZ76752.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.1 AJZ76752.1 - 0.03 14.1 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rio2_N PF09202.6 AJZ76752.1 - 0.034 14.2 0.2 0.047 13.7 0.1 1.2 1 0 0 1 1 1 0 Rio2, N-terminal WSN PF02206.13 AJZ76752.1 - 0.051 13.3 0.3 0.085 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function Rrf2 PF02082.15 AJZ76752.1 - 0.11 12.6 0.3 0.23 11.6 0.1 1.6 1 1 0 1 1 1 0 Transcriptional regulator GATase PF00117.23 AJZ76753.1 - 2.1e-22 79.5 0.0 2.8e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AJZ76753.1 - 3.5e-07 29.8 0.0 6.4e-07 29.0 0.0 1.4 2 0 0 2 2 2 1 Peptidase C26 HTS PF04204.11 AJZ76753.1 - 0.00076 18.2 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 Homoserine O-succinyltransferase ATP-grasp_5 PF13549.1 AJZ76754.1 - 8.4e-69 231.1 0.7 1.3e-68 230.5 0.5 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 AJZ76754.1 - 7e-50 168.2 0.1 9e-49 164.6 0.1 2.7 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 AJZ76754.1 - 1.4e-27 96.1 0.7 4.7e-27 94.4 0.5 2.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 AJZ76754.1 - 8.6e-11 42.2 4.0 1.5e-10 41.4 0.3 3.3 4 0 0 4 4 4 1 CoA binding domain ATP-grasp_2 PF08442.5 AJZ76754.1 - 1.6e-07 30.9 1.0 3.8e-07 29.7 0.7 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 AJZ76754.1 - 0.00022 20.9 0.1 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain TPP_enzyme_M PF00205.17 AJZ76754.1 - 0.00082 19.1 0.1 0.76 9.5 0.0 3.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Semialdhyde_dh PF01118.19 AJZ76754.1 - 0.018 15.3 1.5 0.41 10.9 0.2 3.4 3 1 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain ATP-grasp PF02222.17 AJZ76754.1 - 0.066 12.5 0.1 0.16 11.3 0.1 1.7 1 0 0 1 1 1 0 ATP-grasp domain HMGL-like PF00682.14 AJZ76755.1 - 1.6e-68 230.8 0.1 2.3e-68 230.3 0.1 1.1 1 0 0 1 1 1 1 HMGL-like DUF1629 PF07791.6 AJZ76755.1 - 0.061 13.2 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1629) Semialdhyde_dh PF01118.19 AJZ76756.1 - 1.4e-34 118.9 0.0 2.4e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.13 AJZ76756.1 - 9.1e-18 64.7 0.0 1.6e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain GFO_IDH_MocA PF01408.17 AJZ76756.1 - 0.00018 21.9 0.0 0.00041 20.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 AJZ76756.1 - 0.00047 20.0 0.0 0.00091 19.1 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 AJZ76756.1 - 0.0059 15.6 0.0 0.0081 15.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 AJZ76756.1 - 0.048 14.0 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent BPD_transp_1 PF00528.17 AJZ76757.1 - 1.3e-24 86.7 14.8 2.4e-24 85.8 10.3 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Ifi-6-16 PF06140.8 AJZ76757.1 - 0.0066 16.2 1.3 0.02 14.6 0.9 1.9 1 1 0 1 1 1 1 Interferon-induced 6-16 family Tubulin PF00091.20 AJZ76758.1 - 4.8e-14 52.6 0.1 7.1e-13 48.8 0.0 2.1 1 1 1 2 2 2 1 Tubulin/FtsZ family, GTPase domain Myosin_TH1 PF06017.8 AJZ76758.1 - 0.13 11.5 1.0 0.18 11.0 0.7 1.2 1 0 0 1 1 1 0 Myosin tail Metallophos PF00149.23 AJZ76759.1 - 8.7e-12 44.8 1.7 2e-11 43.7 1.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AJZ76759.1 - 2.8e-10 40.2 0.1 4.5e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF87 PF01935.12 AJZ76760.1 - 3.9e-37 128.2 0.9 6.7e-37 127.5 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 AJZ76760.1 - 5.1e-18 65.5 1.6 1e-11 44.8 0.2 2.3 1 1 0 2 2 2 2 AAA-like domain DUF853 PF05872.7 AJZ76760.1 - 3.1e-06 25.8 0.0 0.0082 14.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) HAS-barrel PF09378.5 AJZ76760.1 - 4.3e-05 23.3 0.1 0.00012 21.8 0.1 1.8 1 0 0 1 1 1 1 HAS barrel domain Zot PF05707.7 AJZ76760.1 - 0.0043 16.5 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) ABC_tran PF00005.22 AJZ76760.1 - 0.014 15.6 0.1 0.061 13.6 0.0 2.0 1 1 1 2 2 2 0 ABC transporter TrwB_AAD_bind PF10412.4 AJZ76760.1 - 0.023 13.3 0.0 0.046 12.3 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 AJZ76760.1 - 0.053 13.4 0.2 12 5.7 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain DUF108 PF01958.13 AJZ76762.1 - 2.2e-34 117.5 0.5 4.9e-34 116.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.11 AJZ76762.1 - 2e-18 66.8 0.0 3.9e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 AJZ76762.1 - 2.7e-06 27.9 0.1 9.2e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 AJZ76762.1 - 0.00015 21.6 0.0 0.00037 20.3 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 AJZ76762.1 - 0.00045 20.5 0.1 0.0011 19.3 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 AJZ76762.1 - 0.0029 17.4 0.4 0.0094 15.7 0.0 2.1 2 1 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AJZ76762.1 - 0.0053 17.1 1.5 0.0084 16.5 0.1 2.0 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 AJZ76762.1 - 0.008 15.3 0.1 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 AJZ76762.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 AJZ76762.1 - 0.042 13.5 0.2 0.59 9.7 0.1 2.6 2 2 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 AJZ76762.1 - 0.83 9.4 3.5 4.9 6.9 1.8 2.8 1 1 0 1 1 1 0 ThiF family