# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Peptidase_Mx PF15887.5 AJZ75045.1 - 0.00014 21.4 2.9 0.00038 19.9 2.9 1.6 1 1 0 1 1 1 1 Putative zinc-binding metallo-peptidase Peptidase_Mx1 PF15890.5 AJZ75045.1 - 0.0053 16.2 1.2 0.022 14.2 1.2 2.1 1 1 0 1 1 1 1 Putative zinc-binding metallo-peptidase ParE_toxin PF05016.15 AJZ75046.1 - 4.8e-13 49.5 0.1 5.4e-13 49.4 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE KH_2 PF07650.17 AJZ75046.1 - 0.031 14.1 0.5 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 KH domain VAPB_antitox PF02697.14 AJZ75047.1 - 5.8e-07 30.2 2.4 7.9e-07 29.8 1.5 1.7 1 1 1 2 2 2 1 Putative antitoxin V-ATPase_G PF03179.15 AJZ75047.1 - 0.017 15.6 0.9 0.053 14.1 0.1 1.9 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Gag_p24 PF00607.20 AJZ75047.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.4 1 1 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) RNA_pol_A_CTD PF03118.15 AJZ75047.1 - 0.08 12.7 2.7 0.61 9.9 0.1 2.5 2 1 1 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain QRPTase_C PF01729.19 AJZ75048.1 - 3.9e-52 176.4 1.3 5.2e-52 176.0 1.3 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AJZ75048.1 - 2.5e-26 91.5 0.5 9.4e-26 89.7 0.1 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.19 AJZ75048.1 - 0.0014 18.0 0.1 0.0035 16.7 0.1 1.6 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.17 AJZ75048.1 - 0.024 14.0 0.1 0.053 12.8 0.1 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase Aldolase PF01081.19 AJZ75048.1 - 0.046 13.1 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase KH_1 PF00013.29 AJZ75048.1 - 0.046 13.5 1.7 0.077 12.8 0.0 2.2 3 0 0 3 3 3 0 KH domain PAS_9 PF13426.7 AJZ75048.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.8 1 1 0 1 1 1 0 PAS domain Spt4 PF06093.13 AJZ75049.1 - 1.7e-12 47.3 0.5 2.2e-12 46.9 0.5 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TackOD1 PF18551.1 AJZ75049.1 - 0.093 12.4 2.1 0.11 12.1 2.1 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-RRN7 PF11781.8 AJZ75049.1 - 2 8.1 6.5 0.94 9.2 0.2 2.1 1 1 1 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 ParA PF10609.9 AJZ75050.1 - 3.1e-100 334.7 0.1 3.8e-100 334.4 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 AJZ75050.1 - 3.4e-20 72.0 0.7 8.3e-19 67.5 0.1 2.6 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 AJZ75050.1 - 1.7e-14 53.9 0.0 4.1e-14 52.7 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AJZ75050.1 - 5e-10 39.6 1.7 2.1e-08 34.3 0.5 2.3 1 1 1 2 2 2 1 AAA domain MipZ PF09140.11 AJZ75050.1 - 7.5e-08 32.0 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 AJZ75050.1 - 7.5e-08 32.1 0.0 9.8e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AJZ75050.1 - 8.6e-06 25.1 1.5 3.8e-05 23.0 0.5 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 AJZ75050.1 - 0.00024 21.0 0.3 0.43 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain VirC1 PF07015.11 AJZ75050.1 - 0.00094 18.5 0.1 0.0019 17.5 0.1 1.5 1 0 0 1 1 1 1 VirC1 protein CLP1_P PF16575.5 AJZ75050.1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CBP_BcsQ PF06564.12 AJZ75050.1 - 0.0069 15.9 0.1 0.025 14.1 0.1 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 AJZ75050.1 - 0.012 15.2 0.6 0.024 14.2 0.6 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AJZ75050.1 - 0.016 14.2 0.3 0.026 13.5 0.3 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 AJZ75050.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase BON PF04972.17 AJZ75050.1 - 0.11 12.8 1.9 0.6 10.4 1.9 2.2 1 1 0 1 1 1 0 BON domain HMA PF00403.26 AJZ75050.1 - 0.12 12.8 0.1 0.33 11.4 0.1 1.8 1 1 0 1 1 1 0 Heavy-metal-associated domain DUF359 PF04019.12 AJZ75051.1 - 1.1e-35 122.0 0.0 1.5e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF359) Pyrophosphatase PF00719.19 AJZ75052.1 - 5.1e-56 188.9 0.3 6e-56 188.7 0.3 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase SprT-like PF10263.9 AJZ75053.1 - 0.0001 22.1 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 SprT-like family DUF45 PF01863.17 AJZ75053.1 - 0.00091 19.3 0.0 0.00091 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_M76 PF09768.9 AJZ75053.1 - 0.043 13.6 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase M76 family Peptidase_M78 PF06114.13 AJZ75053.1 - 0.15 12.0 0.1 0.3 11.0 0.1 1.5 1 1 0 1 1 1 0 IrrE N-terminal-like domain UPF0262 PF06793.12 AJZ75055.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Cyclophil_like PF04126.13 AJZ75056.1 - 1.3e-33 115.4 0.0 1.4e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 AJZ75056.1 - 0.00022 21.2 0.0 0.00028 20.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin-like family Prok-JAB PF14464.6 AJZ75057.1 - 2.1e-20 72.6 0.0 2.4e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 AJZ75057.1 - 8.5e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Toxin-JAB1 PF15659.6 AJZ75057.1 - 0.029 14.7 0.1 0.05 14.0 0.1 1.4 1 0 0 1 1 1 0 JAB-like toxin 1 RadC PF04002.15 AJZ75057.1 - 0.037 14.0 0.4 0.076 13.0 0.2 1.9 2 1 0 2 2 2 0 RadC-like JAB domain Cadherin_5 PF17892.1 AJZ75057.1 - 0.062 13.3 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Cadherin-like domain UbiA PF01040.18 AJZ75058.1 - 9.9e-50 169.2 22.4 1.2e-49 168.9 22.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1129 PF06570.11 AJZ75058.1 - 0.12 11.9 11.3 1.2 8.5 4.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) UL42 PF17638.2 AJZ75058.1 - 0.22 11.5 2.4 0.3 11.1 0.8 2.0 2 0 0 2 2 2 0 HCMV UL42 DUF1456 PF07308.13 AJZ75059.1 - 0.022 15.1 1.4 0.083 13.2 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1456) EF1_GNE PF00736.19 AJZ75060.1 - 1.3e-14 54.1 0.0 1.6e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain FAD_binding_3 PF01494.19 AJZ75061.1 - 1.3e-08 34.5 1.4 1.2e-06 28.0 0.4 2.4 1 1 1 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 AJZ75061.1 - 7.7e-06 25.2 0.0 0.0013 17.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 AJZ75061.1 - 2.7e-05 23.1 1.2 8.3e-05 21.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 AJZ75061.1 - 4.2e-05 22.8 0.4 7.4e-05 22.0 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AJZ75061.1 - 5.3e-05 23.0 3.0 0.0015 18.2 1.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AJZ75061.1 - 0.00011 21.6 3.2 0.0068 15.7 0.6 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AJZ75061.1 - 0.00017 21.1 0.1 0.00024 20.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AJZ75061.1 - 0.00053 19.3 0.3 0.0012 18.1 0.3 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 AJZ75061.1 - 0.0039 17.4 0.3 0.01 16.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 AJZ75061.1 - 0.01 14.7 0.1 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 AJZ75061.1 - 0.031 13.6 0.1 0.45 9.8 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 AJZ75061.1 - 0.13 12.9 3.3 2 9.0 0.2 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PTH2 PF01981.16 AJZ75062.1 - 1.1e-41 141.8 0.1 1.2e-41 141.6 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SGL PF08450.12 AJZ75063.1 - 2e-09 37.4 2.7 0.51 9.9 0.0 4.6 3 2 1 4 4 4 4 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 AJZ75063.1 - 0.12 12.5 0.0 1.2 9.3 0.0 2.7 3 0 0 3 3 3 0 NHL repeat Reg_prop PF07494.11 AJZ75063.1 - 0.21 11.9 3.3 23 5.7 0.0 3.8 3 0 0 3 3 3 0 Two component regulator propeller TruD PF01142.18 AJZ75064.1 - 2.3e-86 290.2 0.0 6.7e-86 288.7 0.0 1.6 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Glycos_transf_2 PF00535.26 AJZ75065.1 - 5.1e-34 117.5 0.0 8.9e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 GtrA PF04138.14 AJZ75065.1 - 9e-21 74.3 11.2 1.3e-20 73.8 9.9 2.0 2 1 0 2 2 2 1 GtrA-like protein Glyco_tranf_2_3 PF13641.6 AJZ75065.1 - 6.4e-09 36.0 0.0 9.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AJZ75065.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 NHL PF01436.21 AJZ75067.1 - 4e-32 108.6 2.3 1.2e-05 25.1 0.0 7.7 8 0 0 8 8 8 5 NHL repeat Thioredoxin_8 PF13905.6 AJZ75067.1 - 7.1e-13 48.7 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 AJZ75067.1 - 1.9e-12 47.1 0.0 5.1e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJZ75067.1 - 1.7e-09 37.5 0.0 3.9e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 AJZ75067.1 - 0.00036 20.5 0.0 0.058 13.4 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin SGL PF08450.12 AJZ75067.1 - 0.0041 16.7 0.3 1.9 8.0 0.2 3.9 3 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Thioredoxin_2 PF13098.6 AJZ75067.1 - 0.0096 16.4 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain PQQ_3 PF13570.6 AJZ75067.1 - 0.0096 16.4 8.7 0.85 10.2 0.5 5.7 5 1 1 6 6 6 1 PQQ-like domain OLF PF02191.16 AJZ75067.1 - 0.016 14.7 0.0 41 3.6 0.0 3.8 3 1 1 4 4 4 0 Olfactomedin-like domain VCBS PF13517.6 AJZ75067.1 - 0.03 14.9 0.6 2.7 8.6 0.0 3.8 4 1 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella AsnC_trans_reg PF01037.21 AJZ75068.1 - 1.8e-11 43.8 0.2 2e-11 43.7 0.2 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 AJZ75068.1 - 0.01 15.8 0.4 0.013 15.5 0.4 1.1 1 0 0 1 1 1 0 NapD protein GYD PF08734.11 AJZ75068.1 - 0.038 13.9 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 GYD domain Tup_N PF08581.10 AJZ75068.1 - 0.16 12.3 1.1 1.1 9.6 0.4 2.0 1 1 1 2 2 2 0 Tup N-terminal DUF2561 PF10812.8 AJZ75069.1 - 0.0044 17.1 0.3 0.0047 17.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) DUF4536 PF15055.6 AJZ75069.1 - 0.22 11.8 0.5 0.22 11.8 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DUF2905 PF11146.8 AJZ75069.1 - 0.84 9.9 6.5 0.65 10.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) DUF202 PF02656.15 AJZ75069.1 - 0.96 9.9 5.0 2.2 8.8 5.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) HMG_box_2 PF09011.10 AJZ75070.1 - 0.0067 17.0 0.3 0.016 15.8 0.3 1.7 1 0 0 1 1 1 1 HMG-box domain COX6A PF02046.15 AJZ75070.1 - 0.015 15.7 0.3 0.026 15.0 0.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa GET2 PF08690.10 AJZ75070.1 - 0.016 14.9 9.5 0.021 14.5 9.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Lant_dehydr_C PF14028.6 AJZ75070.1 - 0.069 12.7 0.0 0.08 12.5 0.0 1.1 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Vps54 PF07928.12 AJZ75070.1 - 0.22 12.0 2.6 14 6.1 0.8 2.2 1 1 1 2 2 2 0 Vps54-like protein PMT_2 PF13231.6 AJZ75071.1 - 8.4e-17 61.8 18.4 8.4e-17 61.8 18.4 2.6 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 AJZ75071.1 - 9.3e-05 22.1 20.3 9.3e-05 22.1 20.3 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase EpsG PF14897.6 AJZ75071.1 - 0.00063 19.2 37.5 0.00087 18.7 22.7 2.2 2 0 0 2 2 2 2 EpsG family DIE2_ALG10 PF04922.12 AJZ75071.1 - 0.0014 18.0 8.7 0.0014 18.0 8.7 2.1 2 0 0 2 2 2 1 DIE2/ALG10 family DUF3506 PF12014.8 AJZ75071.1 - 0.069 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) GT87 PF09594.10 AJZ75071.1 - 0.54 9.9 16.4 0.066 12.9 10.2 2.3 2 1 0 2 2 2 0 Glycosyltransferase family 87 MutS_II PF05188.17 AJZ75075.1 - 0.081 13.2 0.1 0.09 13.1 0.1 1.1 1 0 0 1 1 1 0 MutS domain II FBPase PF00316.20 AJZ75075.1 - 0.13 11.7 0.2 0.14 11.7 0.2 1.0 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Chordopox_A30L PF06015.12 AJZ75076.1 - 0.044 13.6 2.5 5.2 7.0 0.9 2.4 1 1 1 2 2 2 0 Chordopoxvirus A30L protein Thioredox_DsbH PF03190.15 AJZ75077.1 - 3e-77 258.1 0.2 4.9e-77 257.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 AJZ75077.1 - 5.7e-12 45.6 0.0 1.2e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.13 AJZ75077.1 - 2.5e-08 33.7 4.0 0.0012 18.4 0.2 3.3 3 0 0 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 AJZ75077.1 - 1.6e-05 24.2 0.4 0.057 12.5 0.3 3.2 2 2 0 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 AJZ75077.1 - 9.6e-05 22.1 1.7 0.19 11.2 0.2 3.0 2 1 1 3 3 3 2 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.11 AJZ75077.1 - 0.0013 18.0 1.4 0.46 9.7 0.8 2.5 2 1 0 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Pec_lyase PF09492.10 AJZ75077.1 - 0.0028 17.0 0.7 0.99 8.7 0.0 2.8 3 0 0 3 3 3 2 Pectic acid lyase Thioredoxin_2 PF13098.6 AJZ75077.1 - 0.0042 17.5 0.0 0.012 16.1 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_hydro_127 PF07944.12 AJZ75077.1 - 0.019 13.5 3.2 0.044 12.3 1.0 2.3 2 1 1 3 3 3 0 Beta-L-arabinofuranosidase, GH127 DUF5106 PF17127.4 AJZ75077.1 - 0.19 12.0 1.7 0.34 11.2 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5106) Arcadin_1 PF18653.1 AJZ75078.1 - 0.00084 19.4 0.6 0.0011 19.0 0.6 1.3 1 1 0 1 1 1 1 Arcadin 1 MG2 PF01835.19 AJZ75082.1 - 3.6e-06 27.3 0.1 1.2e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 MG2 domain B_lectin PF01453.24 AJZ75082.1 - 0.058 14.0 0.2 0.2 12.2 0.2 2.0 1 1 1 2 2 2 0 D-mannose binding lectin EF-hand_14 PF17959.1 AJZ75083.1 - 0.049 14.0 0.0 0.055 13.8 0.0 1.3 1 1 0 1 1 1 0 EF-hand domain AsnC_trans_reg PF01037.21 AJZ75084.1 - 1.6e-12 47.2 0.1 1.6e-12 47.2 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain DUF2207 PF09972.9 AJZ75085.1 - 0.17 10.6 1.0 0.2 10.4 1.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CPBP PF02517.16 AJZ75086.1 - 0.027 14.8 5.0 0.027 14.8 5.0 3.1 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease NADH_oxidored PF08040.11 AJZ75086.1 - 0.39 10.4 4.3 3 7.6 0.1 2.8 3 0 0 3 3 3 0 MNLL subunit PvlArgDC PF01862.16 AJZ75087.1 - 2e-56 190.3 0.0 2.2e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Peptidase_M3 PF01432.20 AJZ75088.1 - 4.1e-42 145.0 0.9 7.2e-42 144.2 0.9 1.4 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 AJZ75088.1 - 1.9e-05 24.9 0.4 0.00012 22.3 0.2 2.6 2 0 0 2 2 2 1 Oligopeptidase F Peptidase_M78 PF06114.13 AJZ75088.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 IrrE N-terminal-like domain T2SSF PF00482.23 AJZ75088.1 - 0.12 12.3 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F HTH_45 PF14947.6 AJZ75089.1 - 1.3e-07 31.5 2.0 1.6e-07 31.2 2.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.22 AJZ75089.1 - 0.00048 20.0 0.1 0.00073 19.4 0.1 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AJZ75089.1 - 0.044 13.7 0.1 0.069 13.0 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB YbgT_YccB PF08173.11 AJZ75090.1 - 0.57 10.4 3.0 0.88 9.8 2.2 1.8 1 1 0 1 1 1 0 Membrane bound YbgT-like protein Cupredoxin_1 PF13473.6 AJZ75091.1 - 1.4e-09 38.0 0.1 1.8e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Response_reg PF00072.24 AJZ75092.1 - 1.1e-20 73.8 0.1 1.3e-20 73.7 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.19 AJZ75092.1 - 0.094 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain HAD PF12710.7 AJZ75092.1 - 0.18 12.2 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 AJZ75094.1 - 1.7e-24 86.3 0.1 2.7e-24 85.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AJZ75094.1 - 6.9e-21 74.2 0.0 1.2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 AJZ75094.1 - 2e-18 67.8 0.0 3.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.10 AJZ75094.1 - 0.012 15.8 0.2 0.035 14.3 0.0 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Aldo_ket_red PF00248.21 AJZ75095.1 - 1.1e-57 195.5 0.0 1.3e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MCPsignal PF00015.21 AJZ75096.1 - 4.5e-41 140.5 21.9 4.5e-41 140.5 21.9 5.1 2 1 3 5 5 5 3 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AJZ75096.1 - 5.3e-17 62.4 1.5 5.3e-17 62.4 1.5 4.1 3 2 1 4 4 4 1 Cache domain HAMP PF00672.25 AJZ75096.1 - 9.8e-09 35.5 0.3 5.4e-06 26.7 0.0 4.4 4 2 0 4 4 4 1 HAMP domain Hormone_1 PF00103.20 AJZ75096.1 - 0.003 17.3 2.0 0.003 17.3 2.0 4.4 3 2 2 5 5 5 1 Somatotropin hormone family BLOC1_2 PF10046.9 AJZ75096.1 - 0.24 11.7 43.1 0.17 12.2 0.9 6.7 4 2 3 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 AJZ75096.1 - 0.71 10.2 42.1 0.15 12.4 4.9 6.4 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Noelin-1 PF12308.8 AJZ75096.1 - 0.94 9.5 22.9 1.3 9.1 0.7 5.2 5 1 1 6 6 6 0 Neurogenesis glycoprotein Serine_rich PF08824.10 AJZ75096.1 - 0.95 9.4 20.8 2.4 8.1 2.5 4.5 1 1 3 4 4 4 0 Serine rich protein interaction domain Prominin PF05478.11 AJZ75096.1 - 1.1 7.1 27.7 0.059 11.3 6.8 3.3 3 1 0 3 3 3 0 Prominin DUF773 PF05600.12 AJZ75096.1 - 1.4 7.6 30.6 0.18 10.5 0.3 3.5 3 0 0 3 3 3 0 CDK5 regulatory subunit-associated protein 3 Syntaxin_2 PF14523.6 AJZ75096.1 - 4.3 7.8 42.0 0.49 10.8 10.3 5.9 4 2 2 6 6 6 0 Syntaxin-like protein EMG1 PF03587.14 AJZ75097.1 - 0.062 12.9 0.1 0.076 12.7 0.1 1.2 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase dCache_1 PF02743.18 AJZ75098.1 - 3e-13 50.1 0.1 3e-13 50.1 0.1 1.4 2 0 0 2 2 2 1 Cache domain MCPsignal PF00015.21 AJZ75098.1 - 9.1e-12 45.1 0.6 1.4e-11 44.5 0.6 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain TerC PF03741.16 AJZ75099.1 - 9.9e-53 178.5 11.8 9.9e-53 178.5 11.8 1.8 2 0 0 2 2 2 1 Integral membrane protein TerC family DUF475 PF04332.15 AJZ75099.1 - 0.00078 19.3 13.6 0.0049 16.7 12.9 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF475) V_ATPase_I PF01496.19 AJZ75099.1 - 0.094 10.6 0.1 0.13 10.2 0.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family G2BR PF18442.1 AJZ75099.1 - 0.77 9.5 2.0 1.5 8.6 2.0 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) DUF3464 PF11947.8 AJZ75099.1 - 1.8 8.3 4.8 1.7 8.4 1.2 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 CxxCxxCC PF03692.15 AJZ75100.1 - 6.6e-08 33.1 3.9 9.8e-08 32.6 3.9 1.3 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain DZR PF12773.7 AJZ75101.1 - 0.006 16.6 0.6 0.0072 16.3 0.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 AJZ75101.1 - 0.009 15.7 0.5 0.014 15.1 0.5 1.3 1 0 0 1 1 1 1 zinc-ribbon domain Auto_anti-p27 PF06677.12 AJZ75101.1 - 0.012 15.8 2.9 2.2 8.5 0.1 2.1 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_L40e PF01020.17 AJZ75101.1 - 0.024 14.5 6.7 0.035 14.0 6.7 1.4 1 1 0 1 1 1 0 Ribosomal L40e family zf-C2H2_3 PF13878.6 AJZ75101.1 - 0.15 11.9 2.5 0.17 11.7 1.4 1.7 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO ATP-grasp_2 PF08442.10 AJZ75102.1 - 2e-43 148.3 0.7 4.4e-43 147.2 0.7 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 AJZ75102.1 - 1.3e-15 57.4 0.3 4.4e-15 55.7 0.1 1.9 2 1 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 AJZ75102.1 - 1e-13 51.4 1.0 2.2e-13 50.3 1.0 1.5 1 0 0 1 1 1 1 CoA-ligase CPSase_L_D2 PF02786.17 AJZ75102.1 - 1.6e-05 24.5 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 AJZ75102.1 - 5.7e-05 22.8 0.1 0.0001 21.9 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain AdoHcyase_NAD PF00670.21 AJZ75103.1 - 0.07 13.2 0.0 0.083 13.0 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PFK PF00365.20 AJZ75103.1 - 0.14 11.4 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphofructokinase tRNA-synt_1 PF00133.22 AJZ75104.1 - 6.3e-138 460.7 0.1 8.3e-138 460.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AJZ75104.1 - 2.6e-27 95.7 0.3 6.3e-27 94.4 0.3 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AJZ75104.1 - 3.3e-24 85.4 0.4 9.1e-11 41.1 0.1 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AJZ75104.1 - 1.6e-06 27.7 0.0 3.5e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AJZ75104.1 - 0.00066 18.7 0.0 0.0029 16.6 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1_2 PF13603.6 AJZ75104.1 - 0.0023 17.5 0.2 0.0054 16.3 0.2 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Mu-like_Com PF10122.9 AJZ75104.1 - 0.12 11.8 0.8 6.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Mu-like prophage protein Com zinc_ribbon_2 PF13240.6 AJZ75104.1 - 0.17 11.6 2.0 18 5.2 0.5 2.9 2 0 0 2 2 2 0 zinc-ribbon domain GARS_A PF01071.19 AJZ75105.1 - 1.2e-76 256.9 0.1 1.6e-76 256.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 AJZ75105.1 - 7.5e-31 106.8 0.0 2.2e-30 105.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 AJZ75105.1 - 1.5e-28 98.8 0.0 2.9e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain CPSase_L_D2 PF02786.17 AJZ75105.1 - 1.6e-07 31.1 0.0 3.8e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 AJZ75105.1 - 6.1e-07 29.6 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AJZ75105.1 - 1.2e-06 28.2 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 AJZ75105.1 - 0.00015 21.4 0.0 0.00034 20.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AJZ75105.1 - 0.00044 19.9 0.0 0.00099 18.8 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 AJZ75105.1 - 0.00084 18.9 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 AJZ75105.1 - 0.0014 18.1 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AJZ75105.1 - 0.0027 17.0 0.0 0.045 13.0 0.0 2.4 2 1 1 3 3 3 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 AJZ75105.1 - 0.012 15.2 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain 5-FTHF_cyc-lig PF01812.20 AJZ75106.1 - 1.4e-40 139.1 0.0 1.6e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family THF_DHG_CYH_C PF02882.19 AJZ75107.1 - 1.4e-59 199.9 0.6 2.5e-59 199.2 0.6 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 AJZ75107.1 - 2e-37 128.0 0.1 3.2e-37 127.3 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Vps16_N PF04841.13 AJZ75107.1 - 0.05 12.4 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region Sacchrp_dh_NADP PF03435.18 AJZ75107.1 - 0.053 13.8 0.1 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 AJZ75107.1 - 0.06 12.6 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.24 AJZ75107.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Trypsin_2 PF13365.6 AJZ75108.1 - 9e-33 114.3 0.3 1.7e-32 113.4 0.3 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AJZ75108.1 - 5.8e-15 55.4 0.1 2e-14 53.6 0.1 2.0 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 AJZ75108.1 - 1.7e-14 54.2 0.1 3.3e-14 53.2 0.1 1.5 1 1 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 AJZ75108.1 - 1.8e-07 30.9 8.3 0.0034 17.2 0.0 3.8 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 AJZ75108.1 - 1.2e-06 28.8 1.0 0.042 14.2 0.0 3.6 3 0 0 3 3 3 2 PDZ domain Peptidase_S29 PF02907.15 AJZ75108.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Tudor_2 PF18104.1 AJZ75108.1 - 0.0076 15.9 0.1 0.023 14.4 0.0 1.9 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain Peptidase_S7 PF00949.21 AJZ75108.1 - 0.028 14.2 1.4 0.05 13.4 0.4 2.0 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 AJZ75108.1 - 0.031 12.9 0.4 0.045 12.4 0.4 1.2 1 0 0 1 1 1 0 Peptidase S46 Cupin_2 PF07883.11 AJZ75109.1 - 9.5e-11 41.3 0.0 1.7e-10 40.5 0.0 1.4 2 0 0 2 2 2 1 Cupin domain CENP-C_C PF11699.8 AJZ75109.1 - 5.4e-06 26.5 0.0 7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.19 AJZ75109.1 - 0.0014 18.5 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain DMSP_lyase PF16867.5 AJZ75109.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase ARD PF03079.14 AJZ75109.1 - 0.082 13.1 0.1 0.14 12.4 0.0 1.5 2 0 0 2 2 2 0 ARD/ARD' family Ectoine_synth PF06339.12 AJZ75109.1 - 0.09 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Ectoine synthase Formyl_trans_N PF00551.19 AJZ75110.1 - 2.1e-51 174.2 0.0 2.4e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Vps51 PF08700.11 AJZ75112.1 - 0.0018 18.3 0.6 0.0077 16.3 0.6 1.8 1 1 0 1 1 1 1 Vps51/Vps67 Response_reg PF00072.24 AJZ75113.1 - 1.4e-18 67.0 0.1 1.7e-18 66.8 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain 2-Hacid_dh_C PF02826.19 AJZ75113.1 - 0.018 14.4 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_RFF PF18321.1 AJZ75113.1 - 0.087 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain DUF1647 PF07801.11 AJZ75113.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) ArsR PF09824.9 AJZ75114.1 - 0.031 13.9 0.0 0.083 12.5 0.0 1.6 2 0 0 2 2 2 0 ArsR transcriptional regulator RHH_7 PF16777.5 AJZ75114.1 - 0.068 13.6 0.5 9.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Transcriptional regulator, RHH-like, CopG HTH_20 PF12840.7 AJZ75114.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_21 PF05050.12 AJZ75115.1 - 1.4e-16 61.0 0.0 2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 AJZ75115.1 - 1.4e-05 24.6 0.3 1.9e-05 24.1 0.3 1.1 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein YCII PF03795.14 AJZ75116.1 - 0.034 14.6 0.0 0.045 14.2 0.0 1.1 1 0 0 1 1 1 0 YCII-related domain VHS PF00790.19 AJZ75116.1 - 0.12 12.3 0.2 0.18 11.6 0.2 1.2 1 0 0 1 1 1 0 VHS domain MerC PF03203.14 AJZ75118.1 - 0.023 15.1 3.2 0.023 15.1 3.2 2.0 2 1 0 2 2 2 0 MerC mercury resistance protein Bac_export_2 PF01312.19 AJZ75118.1 - 0.69 9.1 3.7 1 8.5 3.7 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family MG2 PF01835.19 AJZ75119.1 - 5e-05 23.7 2.2 0.002 18.6 0.0 3.5 1 1 1 4 4 4 1 MG2 domain PepSY_TM_like_2 PF16357.5 AJZ75119.1 - 0.1 12.6 0.8 0.27 11.2 0.8 1.6 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF1907 PF08925.11 AJZ75119.1 - 0.12 11.8 1.3 0.16 11.4 0.7 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1907) ETRAMP PF09716.10 AJZ75120.1 - 0.14 12.3 1.7 0.27 11.3 1.7 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Hemerythrin PF01814.23 AJZ75121.1 - 1.1e-12 48.7 0.3 2.6e-11 44.3 0.3 2.3 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain BCNT PF07572.12 AJZ75121.1 - 0.053 13.6 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Bucentaur or craniofacial development Copper-bind PF00127.20 AJZ75122.1 - 6.3e-07 29.8 1.6 1e-06 29.1 0.1 2.1 2 1 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJZ75122.1 - 7e-05 22.9 0.0 0.00022 21.3 0.0 1.8 1 1 1 2 2 2 1 Cupredoxin-like domain RR_TM4-6 PF06459.12 AJZ75122.1 - 0.025 14.4 2.5 0.033 14.0 2.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4820 PF16091.5 AJZ75122.1 - 0.056 12.8 1.2 0.074 12.4 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PRCC PF10253.9 AJZ75122.1 - 0.16 12.7 3.0 0.17 12.7 3.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting TORC_M PF12885.7 AJZ75122.1 - 0.19 11.6 2.0 0.14 12.1 0.4 1.6 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain DREPP PF05558.12 AJZ75122.1 - 0.48 10.3 16.0 0.64 9.9 16.0 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide DUF2457 PF10446.9 AJZ75122.1 - 2.5 7.2 9.7 2.8 7.0 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nit_Regul_Hom PF10126.9 AJZ75124.1 - 0.03 14.3 0.1 0.036 14.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII Clc-like PF07062.12 AJZ75124.1 - 0.037 13.5 0.4 0.04 13.4 0.4 1.1 1 0 0 1 1 1 0 Clc-like AsnC_trans_reg PF01037.21 AJZ75125.1 - 0.00042 20.2 0.0 0.00044 20.2 0.0 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain DUF1951 PF09188.10 AJZ75125.1 - 0.022 14.7 0.3 0.033 14.2 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1951) YyzF PF14116.6 AJZ75125.1 - 0.13 12.4 0.7 0.21 11.6 0.7 1.4 1 0 0 1 1 1 0 YyzF-like protein UvrC_HhH_N PF08459.11 AJZ75126.1 - 4.3e-46 156.6 0.0 1e-45 155.4 0.0 1.6 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.24 AJZ75126.1 - 2e-11 44.0 1.4 2e-11 44.0 1.4 2.1 2 0 0 2 2 2 1 GIY-YIG catalytic domain UVR PF02151.19 AJZ75126.1 - 4.3e-08 32.7 0.5 1.4e-07 31.0 0.5 1.9 1 0 0 1 1 1 1 UvrB/uvrC motif UvrA_inter PF17760.1 AJZ75127.1 - 4.3e-34 116.9 0.3 1.1e-33 115.6 0.3 1.7 1 0 0 1 1 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 AJZ75127.1 - 9.6e-34 116.0 0.1 1.8e-30 105.5 0.0 4.1 4 0 0 4 4 4 1 UvrA DNA-binding domain ABC_tran PF00005.27 AJZ75127.1 - 7.5e-25 88.0 1.1 6.3e-10 39.7 0.1 4.9 4 1 0 4 4 4 3 ABC transporter SMC_N PF02463.19 AJZ75127.1 - 8.3e-11 41.7 0.7 0.012 15.1 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AJZ75127.1 - 3e-09 37.5 0.1 0.0046 17.3 0.0 3.8 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 AJZ75127.1 - 3.8e-07 29.8 0.3 0.034 13.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AJZ75127.1 - 7.6e-07 29.2 0.2 0.01 15.8 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase NB-ARC PF00931.22 AJZ75127.1 - 1e-06 28.2 0.1 0.45 9.6 0.0 4.2 4 0 0 4 4 4 1 NB-ARC domain AAA_33 PF13671.6 AJZ75127.1 - 4.2e-06 27.0 0.1 0.2 11.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 AJZ75127.1 - 4.6e-06 26.7 0.0 0.27 11.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.6 AJZ75127.1 - 1.4e-05 25.7 2.4 0.0049 17.4 0.1 3.2 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.6 AJZ75127.1 - 2e-05 24.6 6.3 0.03 14.1 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AJZ75127.1 - 2.5e-05 24.6 3.3 0.19 12.0 0.0 4.5 5 0 0 5 5 4 2 AAA domain AAA_15 PF13175.6 AJZ75127.1 - 5.4e-05 23.1 2.7 0.81 9.3 0.0 4.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_18 PF13238.6 AJZ75127.1 - 6.9e-05 23.4 0.1 0.24 11.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 AJZ75127.1 - 0.00019 21.4 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain T2SSE PF00437.20 AJZ75127.1 - 0.00027 20.1 0.2 0.47 9.5 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein ATPase PF06745.13 AJZ75127.1 - 0.00042 19.7 0.0 0.97 8.7 0.0 2.5 2 0 0 2 2 2 2 KaiC DnaJ_CXXCXGXG PF00684.19 AJZ75127.1 - 0.00056 20.2 7.5 0.039 14.3 0.5 3.8 3 1 0 3 3 3 1 DnaJ central domain AAA_25 PF13481.6 AJZ75127.1 - 0.00061 19.4 0.0 0.34 10.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 AJZ75127.1 - 0.00076 19.4 0.8 1.5 8.7 0.0 2.8 3 0 0 3 3 2 2 Adenylylsulphate kinase Viral_helicase1 PF01443.18 AJZ75127.1 - 0.0012 18.6 0.0 0.19 11.5 0.1 2.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase cobW PF02492.19 AJZ75127.1 - 0.0016 18.1 0.8 0.36 10.4 0.2 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 AJZ75127.1 - 0.0016 17.8 0.0 1.2 8.4 0.1 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 AJZ75127.1 - 0.0021 18.1 0.7 0.51 10.4 0.1 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 AJZ75127.1 - 0.0082 16.5 0.0 2.3 8.6 0.0 3.0 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 AJZ75127.1 - 0.0088 16.0 0.1 4.3 7.2 0.0 2.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 AJZ75127.1 - 0.011 15.7 0.5 0.95 9.4 0.1 3.3 3 0 0 3 3 3 0 NTPase MeaB PF03308.16 AJZ75127.1 - 0.018 14.1 0.1 0.29 10.1 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 AJZ75127.1 - 0.03 13.6 0.1 2.8 7.2 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 AJZ75127.1 - 0.03 14.0 0.1 8.3 6.1 0.1 2.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 AJZ75127.1 - 0.034 13.5 0.5 1.8 7.8 0.1 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family BCA_ABC_TP_C PF12399.8 AJZ75127.1 - 0.036 14.0 0.0 0.43 10.6 0.0 2.6 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter AAA_7 PF12775.7 AJZ75127.1 - 0.056 13.0 0.1 4.1 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 AJZ75127.1 - 0.11 12.7 0.2 23 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AJZ75127.1 - 0.12 12.7 1.3 29 5.0 0.1 3.9 4 1 0 4 4 3 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 AJZ75127.1 - 0.59 9.8 6.0 8.9 6.0 0.1 3.8 4 0 0 4 4 4 0 AAA domain zinc_ribbon_2 PF13240.6 AJZ75127.1 - 2.2 8.1 5.2 27 4.6 0.3 2.8 2 0 0 2 2 2 0 zinc-ribbon domain UvrB_inter PF17757.1 AJZ75128.1 - 3.8e-29 100.7 1.4 7.7e-29 99.7 0.4 2.1 2 0 0 2 2 2 1 UvrB interaction domain UvrB PF12344.8 AJZ75128.1 - 3.2e-20 71.7 2.1 3.2e-20 71.7 2.1 2.3 2 0 0 2 2 2 1 Ultra-violet resistance protein B Helicase_C PF00271.31 AJZ75128.1 - 4.4e-19 68.9 1.5 1.3e-18 67.3 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AJZ75128.1 - 1.2e-09 38.4 5.9 6.9e-09 35.9 0.2 3.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AJZ75128.1 - 1.3e-06 28.2 0.7 0.00037 20.3 0.1 3.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase UVR PF02151.19 AJZ75128.1 - 4.8e-06 26.1 7.2 6e-06 25.8 4.8 2.7 2 0 0 2 2 1 1 UvrB/uvrC motif AAA_30 PF13604.6 AJZ75128.1 - 0.00042 20.1 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AJZ75128.1 - 0.0052 17.1 0.6 2.5 8.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain Met_synt_B12 PF02965.17 AJZ75128.1 - 0.013 15.0 0.7 0.037 13.5 0.2 2.0 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain AAA_7 PF12775.7 AJZ75128.1 - 0.026 14.0 0.4 0.058 12.9 0.4 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 AJZ75128.1 - 0.047 13.9 0.1 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AJZ75128.1 - 0.075 13.5 0.2 3 8.3 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 AJZ75128.1 - 0.085 12.3 1.8 1.3 8.4 0.2 2.5 2 0 0 2 2 2 0 PhoH-like protein UB2H PF14814.6 AJZ75128.1 - 0.099 12.7 0.0 0.36 10.9 0.0 2.1 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain DUF2785 PF10978.8 AJZ75128.1 - 0.13 12.0 0.3 0.42 10.4 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) RecG_N PF17190.4 AJZ75128.1 - 4.5 8.1 10.1 7.1 7.4 0.3 3.8 4 0 0 4 4 3 0 RecG N-terminal helical domain UvrD-helicase PF00580.21 AJZ75128.1 - 5 6.6 14.0 13 5.2 1.5 3.1 2 2 0 2 2 2 0 UvrD/REP helicase N-terminal domain Pyridox_ox_2 PF12900.7 AJZ75130.1 - 2.1e-19 69.9 0.0 2.8e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 AJZ75130.1 - 9.6e-13 48.1 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 AJZ75130.1 - 0.0092 15.7 0.0 0.013 15.2 0.0 1.4 1 1 0 1 1 1 1 Putative FMN-binding domain Sortilin-Vps10 PF15902.5 AJZ75131.1 - 6.6e-14 51.5 0.0 7.1e-09 35.0 0.0 2.1 1 1 1 2 2 2 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 AJZ75131.1 - 7.3e-08 31.3 17.2 0.075 13.1 0.4 5.7 5 0 0 5 5 5 4 BNR/Asp-box repeat PSII_BNR PF14870.6 AJZ75131.1 - 8.2e-08 31.8 4.7 0.00054 19.3 0.0 3.6 1 1 0 3 3 3 3 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 AJZ75131.1 - 0.0018 17.6 0.4 0.61 9.3 0.0 2.7 1 1 1 2 2 2 2 BNR repeat-like domain SBBP PF06739.11 AJZ75131.1 - 0.0026 17.7 0.8 0.011 15.8 0.1 2.4 2 0 0 2 2 2 1 Beta-propeller repeat DUF4185 PF13810.6 AJZ75131.1 - 0.0028 17.0 6.2 3.3 6.9 0.9 4.2 1 1 2 3 3 3 2 Domain of unknown function (DUF4185) Reg_prop PF07494.11 AJZ75131.1 - 0.008 16.3 0.1 19 5.9 0.0 3.8 4 0 0 4 4 4 2 Two component regulator propeller CHB_HEX_C PF03174.13 AJZ75131.1 - 0.31 11.1 1.0 11 6.1 0.0 3.6 5 0 0 5 5 5 0 Chitobiase/beta-hexosaminidase C-terminal domain YtkA PF13115.6 AJZ75132.1 - 7.2e-10 39.4 0.5 1.1e-09 38.8 0.5 1.3 1 0 0 1 1 1 1 YtkA-like Invasin_D3 PF09134.10 AJZ75132.1 - 9.2e-05 22.7 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 Invasin, domain 3 DUF5060 PF16586.5 AJZ75132.1 - 0.0024 18.2 0.0 0.0034 17.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5060) BatD PF13584.6 AJZ75132.1 - 0.01 14.7 0.1 0.012 14.5 0.1 1.0 1 0 0 1 1 1 0 Oxygen tolerance Filamin PF00630.19 AJZ75132.1 - 0.11 13.3 0.0 0.14 13.0 0.0 1.2 1 0 0 1 1 1 0 Filamin/ABP280 repeat Polysacc_synt_C PF14667.6 AJZ75133.1 - 3.1 7.8 18.7 0.42 10.7 4.8 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain RusA PF05866.11 AJZ75134.1 - 0.02 15.4 2.8 0.25 11.9 2.8 2.1 1 1 0 1 1 1 0 Endodeoxyribonuclease RusA Bac_luciferase PF00296.20 AJZ75135.1 - 1.9e-56 191.8 0.0 2.5e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Fe-ADH PF00465.19 AJZ75136.1 - 3.9e-48 164.1 0.0 1.2e-47 162.5 0.0 1.7 1 1 1 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AJZ75136.1 - 2e-16 60.5 0.0 3.5e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 AJZ75136.1 - 6.1e-05 22.3 0.0 0.064 12.4 0.0 2.2 2 0 0 2 2 2 2 3-dehydroquinate synthase CCDC144C PF14915.6 AJZ75137.1 - 0.0032 16.6 0.0 0.004 16.3 0.0 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Citrate_synt PF00285.21 AJZ75139.1 - 3.6e-126 421.1 0.1 4.1e-126 420.9 0.1 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DHHA1 PF02272.19 AJZ75141.1 - 1e-15 58.3 0.4 1e-15 58.3 0.4 2.1 3 0 0 3 3 3 1 DHHA1 domain DHH PF01368.20 AJZ75141.1 - 0.00032 20.9 0.7 0.00076 19.7 0.4 1.8 1 1 1 2 2 2 1 DHH family DUF4784 PF16023.5 AJZ75141.1 - 0.099 11.6 0.2 0.17 10.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4784) YjgF_endoribonc PF14588.6 AJZ75142.1 - 5.5e-37 127.2 0.0 6.2e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 AJZ75142.1 - 2.7e-20 72.6 0.0 3.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP BON PF04972.17 AJZ75142.1 - 0.15 12.4 0.0 0.92 9.9 0.0 2.3 2 1 1 3 3 3 0 BON domain TM_helix PF05552.12 AJZ75143.1 - 5.2e-12 45.5 10.2 8.1e-07 28.9 2.8 3.4 4 0 0 4 4 4 2 Conserved TM helix MS_channel PF00924.18 AJZ75143.1 - 1.3e-08 34.6 5.6 1.3e-08 34.6 5.6 2.4 3 1 0 3 3 3 1 Mechanosensitive ion channel SieB PF14163.6 AJZ75143.1 - 0.28 10.7 0.0 0.28 10.7 0.0 2.6 2 1 0 2 2 2 0 Super-infection exclusion protein B DUF502 PF04367.13 AJZ75143.1 - 0.48 10.4 6.0 2.7 7.9 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF502) DUF1043 PF06295.12 AJZ75143.1 - 0.63 10.0 3.2 0.79 9.7 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) TrmB PF01978.19 AJZ75144.1 - 6.9e-14 51.5 0.2 1.8e-13 50.2 0.2 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 AJZ75144.1 - 0.08 12.1 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB DUF4351 PF14261.6 AJZ75146.1 - 0.005 16.9 1.3 0.0052 16.8 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4351) ASL_C PF08328.11 AJZ75146.1 - 0.0057 16.7 0.4 0.0078 16.3 0.4 1.3 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal DUF148 PF02520.17 AJZ75146.1 - 0.016 15.3 0.6 0.18 11.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF948 PF06103.11 AJZ75146.1 - 0.13 12.6 0.2 0.3 11.4 0.1 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA PF00004.29 AJZ75147.1 - 1.6e-36 125.7 0.0 2.8e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AJZ75147.1 - 2.8e-08 34.1 0.0 8.4e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) MIT PF04212.18 AJZ75147.1 - 8.9e-08 32.1 1.5 2.1e-07 30.9 1.5 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_16 PF13191.6 AJZ75147.1 - 2.1e-06 28.2 0.0 0.0012 19.3 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Vps4_C PF09336.10 AJZ75147.1 - 3.8e-06 26.8 0.3 0.0001 22.2 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 AJZ75147.1 - 3.3e-05 23.7 0.0 0.00016 21.4 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 AJZ75147.1 - 7.5e-05 22.8 0.1 0.00052 20.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AJZ75147.1 - 0.00026 21.3 0.0 0.016 15.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AJZ75147.1 - 0.0022 18.0 0.0 0.025 14.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 AJZ75147.1 - 0.0038 17.2 1.5 0.59 10.0 0.0 2.9 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AJZ75147.1 - 0.005 16.4 0.1 0.025 14.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 AJZ75147.1 - 0.0052 16.6 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain TIP49 PF06068.13 AJZ75147.1 - 0.0088 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 AJZ75147.1 - 0.012 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AJZ75147.1 - 0.012 15.4 0.1 0.029 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AJZ75147.1 - 0.014 15.8 0.0 0.052 13.9 0.0 2.2 1 1 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 AJZ75147.1 - 0.022 14.0 0.0 0.63 9.2 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain AAA_7 PF12775.7 AJZ75147.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 AJZ75147.1 - 0.027 14.2 0.0 0.089 12.5 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 AJZ75147.1 - 0.027 13.7 0.0 0.063 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 AJZ75147.1 - 0.03 13.7 0.2 2.6 7.4 0.0 2.9 2 1 1 3 3 3 0 KaiC IstB_IS21 PF01695.17 AJZ75147.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 AJZ75147.1 - 0.037 13.4 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AJZ75147.1 - 0.038 14.2 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AJZ75147.1 - 0.067 13.7 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AJZ75147.1 - 0.077 13.0 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 AJZ75147.1 - 0.09 12.0 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.6 AJZ75147.1 - 0.091 13.2 0.5 0.18 12.2 0.1 1.7 2 0 0 2 2 1 0 AAA domain IcmF-related PF06761.12 AJZ75147.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing Sigma54_activat PF00158.26 AJZ75147.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 AJZ75147.1 - 0.2 11.6 0.0 0.53 10.2 0.0 1.7 2 0 0 2 2 1 0 NACHT domain Peptidase_M10 PF00413.24 AJZ75148.1 - 1.6e-10 41.1 1.6 8.3e-10 38.7 1.6 2.0 1 1 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 AJZ75148.1 - 0.00037 20.7 0.2 0.00062 20.0 0.1 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 AJZ75148.1 - 0.00088 18.9 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.6 AJZ75148.1 - 0.032 14.7 0.0 0.065 13.8 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 AJZ75148.1 - 0.087 12.4 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.6 AJZ75148.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like GIY-YIG PF01541.24 AJZ75149.1 - 0.00023 21.4 0.1 0.00032 20.9 0.1 1.3 1 1 0 1 1 1 1 GIY-YIG catalytic domain Ribosomal_L18_c PF14204.6 AJZ75149.1 - 0.011 16.7 0.7 0.014 16.3 0.7 1.2 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region RNA_pol_Rpb5_C PF01191.19 AJZ75149.1 - 0.12 12.3 0.3 0.22 11.4 0.1 1.5 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain AID PF18767.1 AJZ75150.1 - 0.047 13.7 0.0 0.052 13.6 0.0 1.1 1 0 0 1 1 1 0 Activation induced deaminase CPSase_sm_chain PF00988.22 AJZ75151.1 - 1.3e-49 167.3 0.0 3.1e-49 166.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 AJZ75151.1 - 1e-44 152.6 0.0 1.7e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJZ75151.1 - 5.4e-08 32.9 0.4 8.1e-06 25.7 0.4 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 AJZ75151.1 - 0.016 15.0 0.1 0.049 13.4 0.0 1.8 1 1 1 2 2 2 0 DJ-1/PfpI family RBB1NT PF08169.11 AJZ75151.1 - 0.019 15.1 0.3 0.036 14.2 0.3 1.4 1 0 0 1 1 1 0 RBB1NT (NUC162) domain Thump_like PF18096.1 AJZ75151.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 THUMP domain-like AsnC_trans_reg PF01037.21 AJZ75152.1 - 6.1e-07 29.3 0.1 7.2e-07 29.1 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_45 PF14947.6 AJZ75155.1 - 2.1e-09 37.2 1.6 3.4e-09 36.6 1.6 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix PHO4 PF01384.20 AJZ75156.1 - 0.03 13.4 8.4 0.038 13.0 8.4 1.2 1 0 0 1 1 1 0 Phosphate transporter family LrgB PF04172.16 AJZ75156.1 - 0.039 13.5 7.3 0.4 10.2 0.4 2.4 2 1 0 2 2 2 0 LrgB-like family Sigma_reg_N PF13800.6 AJZ75156.1 - 0.42 10.9 0.1 0.42 10.9 0.1 3.1 2 1 3 5 5 5 0 Sigma factor regulator N-terminal Copper-bind PF00127.20 AJZ75157.1 - 6.1e-06 26.6 0.2 2.4e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJZ75157.1 - 6.6e-05 23.0 0.0 0.00022 21.3 0.0 1.9 2 0 0 2 2 2 1 Cupredoxin-like domain MG4 PF17789.1 AJZ75157.1 - 0.0014 18.7 0.2 0.0036 17.4 0.2 1.7 1 1 0 1 1 1 1 Macroglobulin domain MG4 ZirS_C PF16583.5 AJZ75157.1 - 0.0018 17.9 0.4 0.003 17.1 0.4 1.3 1 0 0 1 1 1 1 Zinc-regulated secreted antivirulence protein C-terminal domain Big_1 PF02369.16 AJZ75157.1 - 0.002 18.1 0.9 0.002 18.1 0.9 2.1 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) Invasin_D3 PF09134.10 AJZ75157.1 - 0.0036 17.6 1.9 0.0058 16.9 0.6 2.0 2 0 0 2 2 2 1 Invasin, domain 3 DUF824 PF05688.11 AJZ75157.1 - 0.01 15.7 0.2 0.12 12.2 0.0 2.4 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) DUF2207 PF09972.9 AJZ75157.1 - 0.016 14.0 0.4 0.048 12.4 0.4 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Mog1 PF04603.12 AJZ75157.1 - 0.16 12.4 2.3 0.37 11.2 2.3 1.6 1 1 0 1 1 1 0 Ran-interacting Mog1 protein BsuBI_PstI_RE PF06616.11 AJZ75158.1 - 0.028 13.7 0.1 0.16 11.3 0.0 2.0 1 1 1 2 2 2 0 BsuBI/PstI restriction endonuclease domain DUF365 PF04033.12 AJZ75158.1 - 0.086 13.1 0.3 0.19 12.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF365) TFIIB PF00382.19 AJZ75159.1 - 1.2e-33 115.0 3.7 4.5e-16 58.7 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJZ75159.1 - 2.3e-05 23.8 1.0 4.1e-05 23.0 1.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_AsnC-type PF13404.6 AJZ75159.1 - 0.00026 20.7 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Cyclin_N PF00134.23 AJZ75159.1 - 0.0015 18.2 0.5 0.015 15.1 0.2 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain HTH_11 PF08279.12 AJZ75159.1 - 0.0046 16.9 0.2 0.11 12.5 0.0 2.7 3 0 0 3 3 3 1 HTH domain RB_B PF01857.20 AJZ75159.1 - 0.025 14.6 0.1 0.045 13.8 0.1 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain HTH_Crp_2 PF13545.6 AJZ75159.1 - 0.068 13.2 0.0 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain C1_1 PF00130.22 AJZ75159.1 - 0.12 12.3 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.10 AJZ75159.1 - 0.13 12.0 0.4 0.24 11.2 0.4 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF1059 PF06348.11 AJZ75161.1 - 1.4e-07 31.7 0.1 1.9e-07 31.2 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1059) AAA_lid_9 PF17871.1 AJZ75161.1 - 0.069 13.1 0.0 0.084 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA lid domain UBA_3 PF09288.10 AJZ75162.1 - 0.033 14.0 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain GXWXG PF14231.6 AJZ75162.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 GXWXG protein ATP-synt_F PF01990.17 AJZ75163.1 - 2.1e-13 50.4 0.0 2.3e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF4469 PF14734.6 AJZ75163.1 - 0.039 14.1 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold Trp_syntA PF00290.20 AJZ75163.1 - 0.043 12.7 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain DUF3798 PF12683.7 AJZ75163.1 - 0.093 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) YqhR PF11085.8 AJZ75164.1 - 0.00052 20.0 4.2 0.00096 19.1 4.2 1.4 1 0 0 1 1 1 1 Conserved membrane protein YqhR SPC12 PF06645.13 AJZ75164.1 - 0.5 10.5 0.1 0.5 10.5 0.1 2.8 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Phage_holin_3_6 PF07332.11 AJZ75164.1 - 1.3 9.1 8.7 1.7 8.7 3.4 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Fic PF02661.18 AJZ75165.1 - 8.3e-24 84.3 0.0 1.7e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family ADH_N PF08240.12 AJZ75166.1 - 9.3e-23 80.2 2.5 1.8e-22 79.3 2.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AJZ75166.1 - 5.5e-19 68.4 0.0 9.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AJZ75166.1 - 1e-13 51.3 0.0 1.5e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 AJZ75166.1 - 3.8e-08 34.4 0.1 7.3e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SnoaL_3 PF13474.6 AJZ75167.1 - 7.7e-06 26.2 0.0 1e-05 25.8 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 AJZ75167.1 - 5.5e-05 23.3 0.0 0.00014 22.0 0.0 1.7 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 AJZ75167.1 - 0.0012 19.3 0.0 0.0017 18.7 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) TPP_enzyme_N PF02776.18 AJZ75169.1 - 9.1e-59 197.9 0.0 1.2e-57 194.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 AJZ75169.1 - 4.4e-48 162.5 0.0 8.5e-48 161.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 AJZ75169.1 - 7.2e-44 149.3 0.9 1.5e-43 148.2 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M_2 PF16582.5 AJZ75169.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Middle domain of thiamine pyrophosphate HMGL-like PF00682.19 AJZ75170.1 - 4.2e-87 292.1 0.7 6.9e-87 291.3 0.7 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AJZ75170.1 - 9e-26 90.4 1.4 1.9e-25 89.3 1.4 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain UPF0154 PF03672.13 AJZ75170.1 - 0.0068 16.4 0.4 0.014 15.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Iso_dh PF00180.20 AJZ75171.1 - 5.1e-103 344.9 0.2 6.2e-103 344.6 0.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 AJZ75171.1 - 0.0012 18.4 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA DUF4271 PF14093.6 AJZ75172.1 - 0.002 18.0 4.0 0.0022 17.9 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) DUF2721 PF11026.8 AJZ75172.1 - 3.1 7.7 9.8 0.85 9.5 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) AAA_21 PF13304.6 AJZ75174.1 - 3.5e-18 66.5 13.0 4.8e-17 62.7 13.0 2.3 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AJZ75174.1 - 2.1e-15 57.3 20.9 2.1e-15 57.3 20.9 2.0 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 AJZ75174.1 - 1.3e-06 28.1 2.1 0.0021 17.5 0.8 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AJZ75174.1 - 0.0027 18.2 0.1 0.0027 18.2 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AJZ75174.1 - 0.011 15.5 0.1 0.039 13.7 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain IDEAL PF08858.10 AJZ75174.1 - 0.19 11.5 1.1 0.69 9.7 1.1 2.1 1 0 0 1 1 1 0 IDEAL domain HTH_29 PF13551.6 AJZ75176.1 - 0.0019 18.1 0.0 0.0045 17.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix TnsD PF15978.5 AJZ75176.1 - 0.013 14.5 0.1 0.015 14.4 0.1 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_36 PF13730.6 AJZ75176.1 - 0.084 12.9 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4201 PF13870.6 AJZ75179.1 - 0.076 12.7 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) tRNA-synt_2 PF00152.20 AJZ75180.1 - 1.8e-85 286.8 0.0 2.2e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AJZ75180.1 - 1.9e-09 37.4 0.7 3.3e-09 36.6 0.7 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AJZ75180.1 - 0.014 14.9 0.5 0.43 10.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) ABC_tran PF00005.27 AJZ75182.1 - 1.4e-26 93.6 0.1 2.2e-26 93.0 0.1 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AJZ75182.1 - 2.8e-19 69.4 0.1 5e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AJZ75182.1 - 1.5e-07 31.6 1.2 6.6e-07 29.4 0.2 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AJZ75182.1 - 0.0021 17.6 0.3 0.0021 17.6 0.3 1.7 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SNARE_assoc PF09335.11 AJZ75184.1 - 6.2e-16 59.0 2.9 6.2e-16 59.0 2.9 2.5 2 1 0 2 2 2 1 SNARE associated Golgi protein COG7 PF10191.9 AJZ75184.1 - 0.16 10.2 0.0 0.2 9.9 0.0 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF2975 PF11188.8 AJZ75184.1 - 9.2 6.2 12.5 0.21 11.5 3.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) Pur_DNA_glyco PF02245.16 AJZ75185.1 - 3.6e-59 199.1 0.0 4e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) UDG PF03167.19 AJZ75186.1 - 5.5e-43 146.6 0.0 6.3e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Epimerase_2 PF02350.19 AJZ75186.1 - 0.039 12.8 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Peptidase_C3 PF00548.20 AJZ75186.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) PmbA_TldD PF01523.16 AJZ75187.1 - 8.1e-54 183.3 0.2 9.9e-54 183.1 0.2 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase HATPase_c PF02518.26 AJZ75188.1 - 5.2e-29 101.0 0.1 1.3e-28 99.7 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJZ75188.1 - 3.2e-15 55.9 1.8 7.9e-15 54.7 0.1 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AJZ75188.1 - 9.3e-12 45.1 0.0 5.8e-11 42.6 0.0 2.4 2 0 0 2 2 2 1 HAMP domain PilJ PF13675.6 AJZ75188.1 - 1.2e-10 41.4 0.1 8.2e-08 32.3 0.0 3.3 3 0 0 3 3 3 2 Type IV pili methyl-accepting chemotaxis transducer N-term HATPase_c_3 PF13589.6 AJZ75188.1 - 1.1e-05 25.3 0.0 3.6e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AJZ75188.1 - 0.00042 20.2 0.0 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 GHKL domain HATPase_c_2 PF13581.6 AJZ75188.1 - 0.14 12.2 0.0 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Response_reg PF00072.24 AJZ75189.1 - 6.3e-28 97.2 0.3 7e-28 97.0 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain TackOD1 PF18551.1 AJZ75190.1 - 1.9e-30 105.9 9.6 1.9e-30 105.9 9.6 1.5 2 0 0 2 2 2 1 Thaumarchaeal output domain 1 Response_reg PF00072.24 AJZ75190.1 - 5.3e-21 74.9 0.0 1.2e-20 73.8 0.0 1.6 1 1 0 1 1 1 1 Response regulator receiver domain zinc-ribbons_6 PF07191.12 AJZ75190.1 - 0.0019 18.1 14.7 0.061 13.3 3.5 3.2 1 1 1 2 2 2 1 zinc-ribbons FYVE_2 PF02318.16 AJZ75190.1 - 0.0047 17.1 13.6 0.48 10.6 3.7 2.5 1 1 1 2 2 2 2 FYVE-type zinc finger DnaJ_CXXCXGXG PF00684.19 AJZ75190.1 - 0.0073 16.6 10.1 0.0079 16.5 5.0 2.5 1 1 1 2 2 2 1 DnaJ central domain DZR PF12773.7 AJZ75190.1 - 0.048 13.7 14.2 0.75 9.9 9.2 2.8 1 1 2 3 3 3 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 AJZ75190.1 - 0.075 13.2 20.3 1.7 8.9 0.1 5.4 3 2 2 5 5 5 0 Zinc ribbon domain Tn7_Tnp_TnsA_C PF08721.11 AJZ75190.1 - 0.12 13.1 2.1 0.59 10.8 1.3 2.4 1 1 1 2 2 2 0 TnsA endonuclease C terminal Zn_Tnp_IS1595 PF12760.7 AJZ75190.1 - 0.19 11.7 14.9 0.28 11.2 0.5 3.5 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Anti-TRAP PF15777.5 AJZ75190.1 - 0.36 10.8 8.7 1.2 9.2 2.1 3.4 2 2 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 AJZ75190.1 - 0.56 10.2 15.2 1.5 8.9 2.7 3.6 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_3 PF13920.6 AJZ75190.1 - 0.61 10.0 13.1 9.1 6.2 1.4 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Spt4 PF06093.13 AJZ75190.1 - 0.95 9.6 14.0 2.1 8.5 2.1 3.0 1 1 2 3 3 3 0 Spt4/RpoE2 zinc finger PADR1 PF08063.12 AJZ75190.1 - 1.1 9.1 14.0 1.7 8.5 2.0 3.4 2 1 1 3 3 3 0 PADR1 (NUC008) domain zf_UBZ PF18439.1 AJZ75190.1 - 1.3 8.6 16.8 18 5.0 0.1 5.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger TFIIS_C PF01096.18 AJZ75190.1 - 3.3 7.6 16.6 34 4.4 0.2 5.3 5 0 0 5 5 5 0 Transcription factor S-II (TFIIS) zf-TFIIB PF13453.6 AJZ75190.1 - 4.7 6.6 14.9 2.2 7.7 1.1 3.8 2 1 1 3 3 3 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.6 AJZ75190.1 - 5 7.1 17.6 13 5.8 0.0 5.1 4 1 0 4 4 4 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AJZ75190.1 - 5.8 6.5 18.0 4.9 6.8 4.4 4.2 3 2 0 3 3 3 0 TFIIB zinc-binding T2SSE PF00437.20 AJZ75191.1 - 7e-12 45.0 0.0 1.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein KH_1 PF00013.29 AJZ75191.1 - 2.1e-07 30.7 2.8 6.1e-07 29.2 0.2 2.8 2 0 0 2 2 2 1 KH domain AAA_22 PF13401.6 AJZ75191.1 - 5.5e-05 23.5 0.1 0.18 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain KH_2 PF07650.17 AJZ75191.1 - 0.00015 21.5 0.0 0.00052 19.8 0.0 1.9 1 0 0 1 1 1 1 KH domain Zeta_toxin PF06414.12 AJZ75191.1 - 0.0012 18.1 0.1 0.0037 16.6 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin PIN_4 PF13638.6 AJZ75191.1 - 0.0015 18.8 0.2 0.0042 17.4 0.2 1.8 1 0 0 1 1 1 1 PIN domain E3_UFM1_ligase PF09743.9 AJZ75191.1 - 0.0023 17.6 0.5 0.15 11.6 0.0 2.7 3 0 0 3 3 3 1 E3 UFM1-protein ligase 1 AAA_14 PF13173.6 AJZ75191.1 - 0.0025 17.8 0.0 0.008 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AJZ75191.1 - 0.0025 18.2 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 AJZ75191.1 - 0.003 18.1 0.0 0.019 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 AJZ75191.1 - 0.004 16.4 0.0 0.0082 15.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 AJZ75191.1 - 0.005 17.4 0.0 0.027 15.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter KH_5 PF13184.6 AJZ75191.1 - 0.0064 16.6 0.4 0.025 14.7 0.4 2.1 1 0 0 1 1 1 1 NusA-like KH domain NTPase_1 PF03266.15 AJZ75191.1 - 0.0072 16.3 0.1 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_25 PF13481.6 AJZ75191.1 - 0.0075 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AJZ75191.1 - 0.0075 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein MeaB PF03308.16 AJZ75191.1 - 0.0079 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 AJZ75191.1 - 0.012 15.3 0.0 0.076 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 AJZ75191.1 - 0.012 14.9 1.0 0.093 12.0 0.1 2.7 2 1 0 3 3 3 0 DnaB-like helicase C terminal domain AAA_29 PF13555.6 AJZ75191.1 - 0.026 14.3 0.1 0.067 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 AJZ75191.1 - 0.028 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 AJZ75191.1 - 0.035 13.9 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AJZ75191.1 - 0.036 14.5 0.1 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AJZ75191.1 - 0.045 14.0 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 AJZ75191.1 - 0.049 13.4 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 AJZ75191.1 - 0.061 12.6 1.3 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 AJZ75191.1 - 0.092 12.7 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 AJZ75191.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fe_dep_repress PF01325.19 AJZ75192.1 - 2.5e-20 72.4 1.2 4.3e-20 71.7 1.2 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.15 AJZ75192.1 - 2.1e-15 56.5 0.3 8.4e-15 54.6 0.0 1.9 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain DUF4423 PF14394.6 AJZ75192.1 - 3.9e-05 23.4 0.0 0.00031 20.5 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_27 PF13463.6 AJZ75192.1 - 7.8e-05 23.1 0.0 0.00043 20.7 0.0 2.2 2 1 1 3 3 3 1 Winged helix DNA-binding domain MarR PF01047.22 AJZ75192.1 - 0.0002 21.2 0.1 0.00073 19.4 0.0 1.9 2 1 1 3 3 3 1 MarR family MarR_2 PF12802.7 AJZ75192.1 - 0.00032 20.5 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 MarR family LexA_DNA_bind PF01726.16 AJZ75192.1 - 0.00051 19.8 0.0 0.0015 18.3 0.0 1.8 2 0 0 2 2 1 1 LexA DNA binding domain TrmB PF01978.19 AJZ75192.1 - 0.00064 19.5 0.1 0.001 18.9 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AJZ75192.1 - 0.0011 18.4 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AJZ75192.1 - 0.0023 17.9 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain WYL_3 PF18488.1 AJZ75192.1 - 0.0034 17.7 0.6 0.038 14.4 0.2 2.2 2 0 0 2 2 2 1 WYL domain HTH_micro PF17007.5 AJZ75192.1 - 0.013 14.4 0.3 0.013 14.3 0.3 1.1 1 0 0 1 1 1 0 HTH-like DUF2250 PF10007.9 AJZ75192.1 - 0.013 15.6 0.2 0.031 14.4 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_5 PF01022.20 AJZ75192.1 - 0.016 15.1 0.1 0.042 13.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_34 PF13601.6 AJZ75192.1 - 0.019 15.1 0.3 0.1 12.8 0.1 2.2 1 1 1 2 2 2 0 Winged helix DNA-binding domain HTH_6 PF01418.17 AJZ75192.1 - 0.023 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_45 PF14947.6 AJZ75192.1 - 0.031 14.2 1.1 0.05 13.6 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix PAX PF00292.18 AJZ75192.1 - 0.042 13.8 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain Ribosomal_S19e PF01090.19 AJZ75192.1 - 0.044 13.5 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S19e HTH_12 PF08461.10 AJZ75192.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain Rrf2 PF02082.20 AJZ75192.1 - 0.11 12.8 0.1 0.38 11.1 0.0 1.9 2 1 0 2 2 1 0 Transcriptional regulator HTH_IclR PF09339.10 AJZ75192.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF192 PF02643.15 AJZ75193.1 - 1.2e-30 105.5 0.0 1.5e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 Na_H_antiport_2 PF13726.6 AJZ75193.1 - 0.055 13.6 0.1 0.085 13.0 0.1 1.3 1 0 0 1 1 1 0 Na+-H+ antiporter family TauE PF01925.19 AJZ75194.1 - 7.6e-56 189.4 31.1 8.8e-56 189.2 31.1 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Nepo_coat PF03391.15 AJZ75194.1 - 0.094 12.2 1.5 3.9 6.9 0.1 2.3 2 0 0 2 2 2 0 Nepovirus coat protein, central domain Bac_export_2 PF01312.19 AJZ75194.1 - 0.71 9.0 3.9 0.36 10.0 1.6 1.6 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF3206 PF11472.8 AJZ75195.1 - 0.022 14.8 0.0 0.053 13.5 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3206) adh_short PF00106.25 AJZ75196.1 - 6.9e-34 117.0 0.1 4.5e-27 94.8 0.0 2.9 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 AJZ75196.1 - 2.1e-29 102.8 0.0 1.6e-20 73.7 0.0 3.5 3 1 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJZ75196.1 - 1.3e-08 35.0 0.0 1.2e-07 31.9 0.0 2.5 2 1 1 3 3 3 1 KR domain 3HCDH_N PF02737.18 AJZ75196.1 - 0.013 15.4 0.7 0.041 13.8 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 AJZ75196.1 - 0.034 13.6 0.1 0.19 11.2 0.0 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 7TMR-HDED PF07697.11 AJZ75196.1 - 0.063 13.4 2.5 0.16 12.0 2.5 1.8 1 1 0 1 1 1 0 7TM-HD extracellular DUF1904 PF08921.11 AJZ75196.1 - 0.15 12.3 1.0 1.6 9.1 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1904) NAD_binding_7 PF13241.6 AJZ75196.1 - 0.71 10.3 3.4 3.7 8.0 0.0 3.2 2 1 0 2 2 2 0 Putative NAD(P)-binding EAP30 PF04157.16 AJZ75197.1 - 0.083 12.2 0.0 0.09 12.0 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family tRNA_int_endo PF01974.17 AJZ75199.1 - 1.5e-28 98.7 0.2 3.3e-28 97.6 0.1 1.6 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 AJZ75199.1 - 7.3e-17 60.8 0.0 1.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain PhoU_div PF01865.16 AJZ75200.1 - 2.1e-17 63.2 10.5 2.5e-17 62.9 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 PhoU PF01895.19 AJZ75200.1 - 0.00081 19.8 13.1 0.019 15.4 3.0 3.1 2 2 1 3 3 3 2 PhoU domain COG5 PF10392.9 AJZ75200.1 - 0.0068 16.6 3.2 1.4 9.1 0.0 2.4 2 0 0 2 2 2 2 Golgi transport complex subunit 5 DUF677 PF05055.12 AJZ75200.1 - 0.014 14.4 1.3 0.014 14.4 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF677) DUF2996 PF11210.8 AJZ75200.1 - 0.025 15.0 0.6 0.31 11.5 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2996) DUF3731 PF12531.8 AJZ75200.1 - 0.025 14.4 0.5 0.05 13.4 0.5 1.5 1 0 0 1 1 1 0 DNA-K related protein Glyco_hydro_6 PF01341.17 AJZ75200.1 - 0.066 12.9 0.1 0.77 9.4 0.0 2.0 1 1 1 2 2 2 0 Glycosyl hydrolases family 6 TerB PF05099.13 AJZ75200.1 - 0.078 12.9 1.5 0.17 11.9 0.2 2.1 2 1 0 2 2 2 0 Tellurite resistance protein TerB GP41 PF00517.17 AJZ75200.1 - 0.55 10.1 4.2 0.34 10.8 1.6 1.8 1 1 1 2 2 2 0 Retroviral envelope protein Spc7 PF08317.11 AJZ75200.1 - 0.86 8.4 9.4 0.28 10.0 1.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 AJZ75200.1 - 1.4 9.4 10.3 0.77 10.3 0.1 3.9 1 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 AJZ75200.1 - 1.4 9.0 9.0 0.71 10.0 0.1 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_23 PF13476.6 AJZ75200.1 - 1.6 9.2 10.2 3.2 8.2 1.4 2.2 2 0 0 2 2 2 0 AAA domain WD40_alt PF14077.6 AJZ75200.1 - 2.9 7.8 5.6 0.51 10.2 0.2 2.6 3 0 0 3 3 3 0 Alternative WD40 repeat motif DUF2203 PF09969.9 AJZ75200.1 - 3.3 8.4 7.5 9.1 7.0 1.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) zf-C4H2 PF10146.9 AJZ75200.1 - 4.8 7.4 8.7 2.8 8.2 2.2 2.4 1 1 0 2 2 2 0 Zinc finger-containing protein ABC_tran_CTD PF16326.5 AJZ75200.1 - 4.8 7.5 11.6 18 5.6 1.9 3.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain DNA_ligase_A_M PF01068.21 AJZ75201.1 - 1.4e-60 204.4 2.3 1.6e-60 204.3 0.2 2.2 3 0 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 AJZ75201.1 - 5.2e-36 124.6 0.9 5.2e-36 124.6 0.9 2.0 3 0 0 3 3 3 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 AJZ75201.1 - 1.3e-21 77.0 0.0 3e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 AJZ75201.1 - 4.5e-07 30.3 0.1 7.9e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 AJZ75201.1 - 0.16 12.0 0.1 1 9.5 0.0 2.2 2 0 0 2 2 2 0 DNA ligase OB-like domain FixS PF03597.15 AJZ75203.1 - 0.12 12.1 1.4 0.3 10.8 1.4 1.6 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type TcpE PF12648.7 AJZ75203.1 - 0.16 12.5 4.0 0.09 13.3 1.6 1.8 2 0 0 2 2 2 0 TcpE family FBPase_3 PF01950.16 AJZ75204.1 - 4.9e-146 486.5 0.0 5.6e-146 486.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase GTP_EFTU PF00009.27 AJZ75205.1 - 4.9e-46 156.7 0.0 6.9e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AJZ75205.1 - 2.9e-36 124.2 0.1 9.3e-36 122.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AJZ75205.1 - 4.6e-17 62.2 2.2 3.2e-16 59.5 0.7 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 AJZ75205.1 - 2.5e-05 24.1 0.9 5.6e-05 23.0 0.9 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Ferritin_2 PF13668.6 AJZ75205.1 - 0.037 14.2 0.4 0.11 12.6 0.2 1.8 1 1 0 1 1 1 0 Ferritin-like domain SIMPL PF04402.14 AJZ75205.1 - 0.11 13.0 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Ribosomal_S10 PF00338.22 AJZ75206.1 - 7e-24 83.9 0.0 7.8e-24 83.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CTX_RstB PF07459.11 AJZ75206.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 CTX phage RstB protein DNA_RNApol_7kD PF03604.13 AJZ75207.1 - 0.00059 19.5 2.0 0.0011 18.6 2.0 1.5 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-C4pol PF14260.6 AJZ75208.1 - 0.00028 21.3 10.3 2.1 8.9 3.7 3.2 2 1 1 3 3 3 3 C4-type zinc-finger of DNA polymerase delta YabP PF07873.11 AJZ75208.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 YabP family Prok-RING_4 PF14447.6 AJZ75208.1 - 0.11 12.3 0.9 0.11 12.3 0.9 4.4 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 DZR PF12773.7 AJZ75208.1 - 0.16 12.0 17.0 0.18 11.9 2.9 3.4 2 2 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.6 AJZ75208.1 - 0.18 11.9 0.3 0.18 11.9 0.3 3.3 3 1 0 3 3 3 0 Transposase zinc-binding domain Cytochrome_C7 PF14522.6 AJZ75208.1 - 0.26 11.3 10.8 3.9 7.6 0.1 3.0 3 0 0 3 3 3 0 Cytochrome c7 and related cytochrome c RecO_C PF02565.15 AJZ75208.1 - 0.76 9.6 3.2 4.6 7.0 0.2 2.6 2 1 0 2 2 2 0 Recombination protein O C terminal LDcluster4 PF18306.1 AJZ75209.1 - 1e-45 155.2 0.3 1.1e-45 155.0 0.3 1.0 1 0 0 1 1 1 1 SLOG cluster4 family Lysine_decarbox PF03641.14 AJZ75209.1 - 0.00047 20.3 0.3 0.0028 17.8 0.3 2.3 1 1 0 1 1 1 1 Possible lysine decarboxylase DNA_processg_A PF02481.15 AJZ75209.1 - 0.0037 16.5 0.9 0.054 12.7 0.2 2.2 1 1 0 2 2 2 1 DNA recombination-mediator protein A LSDAT_prok PF18171.1 AJZ75209.1 - 0.015 14.5 0.2 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote DAGK_cat PF00781.24 AJZ75209.1 - 0.59 9.7 4.1 0.92 9.1 0.1 2.5 2 2 0 2 2 2 0 Diacylglycerol kinase catalytic domain 3HCDH_N PF02737.18 AJZ75210.1 - 1.1e-68 230.6 0.8 1.7e-68 230.0 0.8 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AJZ75210.1 - 8.4e-32 109.7 0.0 1.4e-24 86.5 0.0 2.6 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 AJZ75210.1 - 4.5e-06 26.7 0.3 8.7e-06 25.8 0.3 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 AJZ75210.1 - 3.6e-05 24.0 0.1 7.3e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 AJZ75210.1 - 0.0011 18.5 0.5 0.0023 17.5 0.5 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 AJZ75210.1 - 0.0017 18.9 1.4 0.0074 16.8 1.4 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 AJZ75210.1 - 0.037 13.3 0.5 0.07 12.4 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 AJZ75210.1 - 0.04 13.5 2.5 4.1 6.9 2.5 2.3 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 AJZ75210.1 - 0.054 13.8 0.2 0.15 12.3 0.2 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_C PF03720.15 AJZ75210.1 - 0.11 12.9 0.2 0.26 11.7 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Flu_NS2 PF00601.19 AJZ75210.1 - 0.12 12.7 0.1 0.39 11.0 0.1 1.8 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) DnaJ PF00226.31 AJZ75211.1 - 4.5e-16 58.7 1.2 9.4e-16 57.7 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain Fer4_13 PF13370.6 AJZ75211.1 - 1.4e-09 38.4 2.6 3.2e-09 37.2 2.6 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AJZ75211.1 - 8.6e-05 23.2 3.9 0.00044 20.9 3.9 2.0 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 AJZ75211.1 - 0.012 15.7 2.9 0.032 14.3 2.9 1.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster DUF4548 PF15081.6 AJZ75211.1 - 0.079 12.8 4.0 2.4 8.0 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4548) Fer4 PF00037.27 AJZ75211.1 - 0.54 10.2 7.2 5.4 7.0 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain AsnC_trans_reg PF01037.21 AJZ75213.1 - 6.8e-08 32.4 0.1 7.3e-08 32.3 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GYD PF08734.11 AJZ75213.1 - 0.039 13.9 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 GYD domain DUF2129 PF09902.9 AJZ75213.1 - 0.14 12.3 1.3 0.15 12.1 0.5 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) Pyr_redox_2 PF07992.14 AJZ75214.1 - 1.3e-28 100.1 0.8 1.7e-28 99.7 0.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AJZ75214.1 - 2.4e-14 53.3 2.5 2.1e-10 40.4 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AJZ75214.1 - 7e-06 25.4 2.0 0.00011 21.4 0.2 2.5 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 AJZ75214.1 - 0.00035 19.9 0.1 0.00079 18.7 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 AJZ75214.1 - 0.001 19.6 2.8 0.0053 17.3 0.1 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AJZ75214.1 - 0.0076 15.0 1.1 0.38 9.4 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 AJZ75214.1 - 0.0089 16.2 0.0 0.031 14.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AJZ75214.1 - 0.0092 15.6 0.5 1.1 8.7 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AJZ75214.1 - 0.011 15.0 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 AJZ75214.1 - 0.012 15.0 0.3 0.064 12.6 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 AJZ75214.1 - 0.086 12.0 0.1 36 3.3 0.0 3.0 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 AJZ75214.1 - 0.086 12.8 0.3 15 5.5 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 AJZ75214.1 - 0.092 11.8 2.3 0.11 11.5 0.2 2.2 2 1 1 3 3 3 0 Glucose inhibited division protein A Ferritin PF00210.24 AJZ75215.1 - 2.3e-21 76.2 0.0 2.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Abhydrolase_1 PF00561.20 AJZ75216.1 - 1e-30 107.3 0.0 9.4e-29 100.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AJZ75216.1 - 4.1e-22 79.9 0.0 4.8e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AJZ75216.1 - 3e-21 75.8 0.0 3.7e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 AJZ75216.1 - 2.3e-05 24.3 0.0 0.03 14.2 0.0 2.3 2 1 0 2 2 2 2 Serine hydrolase Abhydrolase_2 PF02230.16 AJZ75216.1 - 0.00014 21.7 0.0 1.1 9.0 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Ndr PF03096.14 AJZ75216.1 - 0.00022 20.0 0.0 0.00043 19.1 0.0 1.5 1 1 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 AJZ75216.1 - 0.00039 20.5 0.0 0.00066 19.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DUF3530 PF12048.8 AJZ75216.1 - 0.0011 18.5 0.1 0.0018 17.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Abhydrolase_5 PF12695.7 AJZ75216.1 - 0.0011 18.7 0.0 0.72 9.6 0.1 2.6 1 1 2 3 3 3 1 Alpha/beta hydrolase family FSH1 PF03959.13 AJZ75216.1 - 0.0017 18.1 0.0 0.021 14.5 0.0 2.4 1 1 0 2 2 2 1 Serine hydrolase (FSH1) Palm_thioest PF02089.15 AJZ75216.1 - 0.002 18.0 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 AJZ75216.1 - 0.0039 17.1 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 AJZ75216.1 - 0.0085 15.6 0.1 0.017 14.6 0.1 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PAC2 PF09754.9 AJZ75216.1 - 0.024 14.6 0.0 0.072 13.1 0.0 1.9 1 1 0 1 1 1 0 PAC2 family UPF0227 PF05728.12 AJZ75216.1 - 0.025 14.5 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.11 AJZ75216.1 - 0.026 13.9 0.0 0.25 10.6 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 AJZ75216.1 - 0.067 13.3 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 AJZ75216.1 - 0.067 12.9 0.1 0.76 9.4 0.1 2.0 1 1 1 2 2 2 0 PGAP1-like protein PhaC_N PF07167.13 AJZ75217.1 - 3.3e-13 49.6 0.2 6e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Hydrolase_4 PF12146.8 AJZ75217.1 - 1.4e-12 47.4 0.0 2.8e-11 43.1 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AJZ75217.1 - 1.5e-12 47.7 0.0 5.9e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3141 PF11339.8 AJZ75217.1 - 2.2e-08 33.0 0.1 3.4e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3141) BAAT_C PF08840.11 AJZ75217.1 - 0.00014 21.9 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 AJZ75217.1 - 0.00058 19.5 0.0 0.0084 15.7 0.0 2.3 3 0 0 3 3 3 1 Dienelactone hydrolase family PHB_depo_C PF06850.11 AJZ75217.1 - 0.00058 19.4 0.0 0.0056 16.2 0.0 2.3 1 1 1 2 2 2 1 PHB de-polymerase C-terminus PDDEXK_10 PF07788.11 AJZ75217.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily PHA_synth_III_E PF09712.10 AJZ75218.1 - 4.4e-19 68.7 2.4 5e-19 68.5 1.9 1.3 1 1 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) TelA PF05816.11 AJZ75218.1 - 0.00071 18.7 1.4 0.31 10.0 0.2 2.1 2 0 0 2 2 2 2 Toxic anion resistance protein (TelA) DUF2408 PF10303.9 AJZ75218.1 - 0.00086 19.9 2.6 0.0012 19.4 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) Myb_DNA-bind_5 PF13873.6 AJZ75218.1 - 0.00094 19.2 4.7 0.0089 16.1 0.7 2.3 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Bacillus_HBL PF05791.11 AJZ75218.1 - 0.00097 19.0 2.2 0.0081 16.0 0.4 2.2 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) BMFP PF04380.13 AJZ75218.1 - 0.0021 18.5 1.1 0.015 15.8 0.2 2.4 2 1 1 3 3 3 1 Membrane fusogenic activity Phasin PF05597.11 AJZ75218.1 - 0.0073 16.3 1.5 0.051 13.6 1.5 2.1 1 1 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) YabA PF06156.13 AJZ75218.1 - 0.0077 16.8 1.0 0.89 10.2 0.0 2.2 2 0 0 2 2 2 1 Initiation control protein YabA Fib_alpha PF08702.10 AJZ75218.1 - 0.014 15.6 1.3 0.27 11.4 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Cnn_1N PF07989.11 AJZ75218.1 - 0.019 15.1 0.8 6.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 AJZ75218.1 - 0.019 15.0 2.1 1.9 8.6 0.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein KxDL PF10241.9 AJZ75218.1 - 0.049 13.9 0.9 9 6.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein MutS_IV PF05190.18 AJZ75218.1 - 0.092 13.1 2.5 4.6 7.6 1.0 2.3 2 0 0 2 2 2 0 MutS family domain IV Retrotrans_gag PF03732.17 AJZ75218.1 - 0.13 12.5 2.2 0.88 9.9 0.4 2.6 1 1 1 2 2 2 0 Retrotransposon gag protein Baculo_PEP_C PF04513.12 AJZ75218.1 - 0.15 12.1 0.0 1 9.4 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 AJZ75218.1 - 0.23 11.4 1.8 1.2 9.1 0.1 2.0 2 0 0 2 2 2 0 Laminin Domain II GAT PF03127.14 AJZ75218.1 - 0.24 11.7 5.3 2.5 8.5 0.2 2.8 2 1 1 3 3 3 0 GAT domain DUF4618 PF15397.6 AJZ75218.1 - 0.25 10.7 6.4 0.62 9.4 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) BLOC1_2 PF10046.9 AJZ75218.1 - 0.3 11.4 3.7 8.8 6.7 0.1 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YkyA PF10368.9 AJZ75218.1 - 0.41 10.3 7.2 0.7 9.5 0.3 2.3 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein Snapin_Pallidin PF14712.6 AJZ75218.1 - 0.46 10.9 3.7 2.2 8.7 0.3 2.3 2 0 0 2 2 2 0 Snapin/Pallidin CREPT PF16566.5 AJZ75218.1 - 0.6 10.3 4.4 3 8.0 2.8 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2730 PF10805.8 AJZ75218.1 - 0.62 10.2 3.7 1 9.5 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) HATPase_c PF02518.26 AJZ75220.1 - 1.4e-20 73.8 0.3 2.8e-20 72.9 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJZ75220.1 - 4.7e-12 45.8 0.1 1e-11 44.7 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJZ75220.1 - 4e-10 39.5 0.4 7.9e-10 38.6 0.4 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AJZ75220.1 - 1.7e-06 27.9 0.6 3.6e-06 26.9 0.2 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AJZ75220.1 - 3.8e-06 26.9 0.1 1e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain DUF1993 PF09351.10 AJZ75220.1 - 0.055 13.6 0.3 0.21 11.7 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) DUF1859 PF08948.10 AJZ75220.1 - 0.11 12.4 0.0 9.7 6.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1859) DREV PF05219.12 AJZ75220.1 - 0.11 11.5 0.1 0.66 9.0 0.1 1.9 2 0 0 2 2 2 0 DREV methyltransferase GIY-YIG PF01541.24 AJZ75221.1 - 0.01 16.1 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain EKAL PF17986.1 AJZ75221.1 - 0.093 12.8 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 EMP3-KAHRP-like N-terminal domain TFIIB PF00382.19 AJZ75222.1 - 3.8e-34 116.6 6.9 2.3e-17 62.8 0.3 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJZ75222.1 - 1e-07 31.4 0.3 1.7e-07 30.6 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 AJZ75222.1 - 4.7e-05 23.1 0.3 0.0016 18.1 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB_C_1 PF18542.1 AJZ75222.1 - 0.0081 16.2 0.4 0.023 14.7 0.4 1.8 1 0 0 1 1 1 1 Transcription factor IIB C-terminal module 1 zf-ribbon_3 PF13248.6 AJZ75222.1 - 0.012 15.0 4.1 0.13 11.7 4.1 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Rrf2 PF02082.20 AJZ75222.1 - 0.027 14.8 0.3 3.7 8.0 0.1 2.9 2 1 1 3 3 3 0 Transcriptional regulator DZR PF12773.7 AJZ75222.1 - 0.058 13.4 1.2 0.12 12.5 1.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon RB_B PF01857.20 AJZ75222.1 - 0.099 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Ribosomal_S27e PF01667.17 AJZ75222.1 - 0.14 11.9 1.7 0.29 10.9 1.2 1.7 2 0 0 2 2 2 0 Ribosomal protein S27 TrmB PF01978.19 AJZ75224.1 - 5.9e-14 51.7 0.0 2.6e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 AJZ75224.1 - 0.0003 20.6 0.0 0.00066 19.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Regulator_TrmB PF11495.8 AJZ75224.1 - 0.00072 18.8 0.0 0.00097 18.4 0.0 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_24 PF13412.6 AJZ75224.1 - 0.0077 15.8 0.3 0.036 13.6 0.0 2.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding RNA_pol_A_CTD PF03118.15 AJZ75224.1 - 0.051 13.3 2.6 0.15 11.9 0.1 2.7 3 0 0 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain HTH_IclR PF09339.10 AJZ75224.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Fcf2 PF08698.11 AJZ75225.1 - 0.038 14.4 0.4 2.8 8.4 0.1 2.1 2 0 0 2 2 2 0 Fcf2 pre-rRNA processing Peptidase_M10 PF00413.24 AJZ75226.1 - 2.8e-09 37.0 0.5 8.9e-09 35.4 0.5 1.9 1 1 0 1 1 1 1 Matrixin TPR_2 PF07719.17 AJZ75226.1 - 7.8e-09 35.0 5.7 0.00067 19.6 0.9 3.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 AJZ75226.1 - 8.7e-09 34.8 4.8 0.043 13.6 1.3 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 AJZ75226.1 - 9.6e-08 32.2 5.9 0.0023 18.5 0.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 AJZ75226.1 - 2.2e-07 31.3 0.1 0.0017 18.8 0.0 2.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 AJZ75226.1 - 8.7e-07 29.3 0.0 0.0022 18.7 0.0 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat Reprolysin_5 PF13688.6 AJZ75226.1 - 1.9e-05 24.9 0.4 4e-05 23.8 0.4 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 TPR_16 PF13432.6 AJZ75226.1 - 5.9e-05 23.6 0.0 0.00057 20.5 0.0 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 AJZ75226.1 - 0.0002 21.6 0.1 0.13 12.6 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat Peptidase_M57 PF12388.8 AJZ75226.1 - 0.00029 20.5 0.1 0.00056 19.6 0.1 1.5 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M54 PF07998.11 AJZ75226.1 - 0.0012 18.9 1.6 0.0042 17.1 0.1 2.2 2 0 0 2 2 2 1 Peptidase family M54 TPR_8 PF13181.6 AJZ75226.1 - 0.0025 17.9 6.9 2.2 8.7 0.6 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Reprolysin_2 PF13574.6 AJZ75226.1 - 0.0029 17.5 0.1 0.0062 16.5 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Fis1_TPR_C PF14853.6 AJZ75226.1 - 0.0036 17.4 0.4 0.087 12.9 0.0 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Peptidase_M66 PF10462.9 AJZ75226.1 - 0.0045 16.0 0.1 0.0099 14.9 0.1 1.6 1 0 0 1 1 1 1 Peptidase M66 TPR_11 PF13414.6 AJZ75226.1 - 0.0056 16.3 0.2 0.016 14.9 0.2 1.9 1 0 0 1 1 1 1 TPR repeat ANAPC3 PF12895.7 AJZ75226.1 - 0.0065 16.7 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 PDZ_3 PF17815.1 AJZ75226.1 - 0.019 14.8 0.2 0.044 13.6 0.2 1.6 1 0 0 1 1 1 0 PDZ domain Reprolysin_3 PF13582.6 AJZ75226.1 - 0.019 15.5 2.8 0.031 14.8 0.2 2.3 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like TPR_7 PF13176.6 AJZ75226.1 - 0.025 14.6 0.1 1.2 9.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 AJZ75226.1 - 0.027 14.8 4.4 0.039 14.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 AJZ75226.1 - 0.071 13.0 0.1 42 4.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Reprolysin_4 PF13583.6 AJZ75226.1 - 0.097 12.3 0.3 0.17 11.5 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 AJZ75226.1 - 0.12 10.9 0.2 0.28 9.7 0.2 1.5 1 0 0 1 1 1 0 Putative peptidase family DUF5113 PF17140.4 AJZ75226.1 - 1.2 8.9 7.9 3.5 7.4 0.7 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF5113) TPR_3 PF07720.12 AJZ75226.1 - 1.4 9.0 8.7 0.21 11.6 3.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat BPL_LplA_LipB PF03099.19 AJZ75227.1 - 5.6e-17 61.9 0.1 9.7e-17 61.1 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.12 AJZ75227.1 - 3.6e-16 58.8 0.2 9.2e-16 57.5 0.2 1.7 1 0 0 1 1 1 1 HTH domain BPL_C PF02237.17 AJZ75227.1 - 1.1e-06 28.4 0.1 2.5e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain BPL_LplA_LipB_2 PF16917.5 AJZ75227.1 - 0.0097 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family UPF0122 PF04297.14 AJZ75227.1 - 0.018 15.2 0.9 0.054 13.7 0.1 2.1 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4_2 PF08281.12 AJZ75227.1 - 0.04 13.6 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Glyco_hyd_101C PF17451.2 AJZ75227.1 - 0.099 12.9 0.5 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain HTH_10 PF04967.12 AJZ75227.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_34 PF13601.6 AJZ75228.1 - 2.2e-06 27.8 0.2 3.5e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AJZ75228.1 - 3.2e-05 23.7 0.0 5.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AJZ75228.1 - 7.7e-05 22.5 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 AJZ75228.1 - 0.00016 21.5 0.5 0.00025 20.9 0.5 1.4 1 1 0 1 1 1 1 TFIIE alpha subunit HTH_45 PF14947.6 AJZ75228.1 - 0.00066 19.6 0.4 0.0022 17.9 0.4 1.8 1 1 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.22 AJZ75228.1 - 0.0017 18.2 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 MarR family DUF4423 PF14394.6 AJZ75228.1 - 0.0024 17.6 0.2 0.0039 16.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_27 PF13463.6 AJZ75228.1 - 0.0059 17.1 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AJZ75228.1 - 0.015 14.8 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PadR PF03551.14 AJZ75228.1 - 0.016 15.1 0.1 0.035 14.1 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Rrf2 PF02082.20 AJZ75228.1 - 0.022 15.1 0.0 0.037 14.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator Ribonuclease_3 PF00636.26 AJZ75228.1 - 0.024 15.2 0.0 0.046 14.3 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease III domain HemN_C PF06969.16 AJZ75228.1 - 0.031 14.3 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 HemN C-terminal domain HTH_20 PF12840.7 AJZ75228.1 - 0.046 13.8 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain SARAF PF06682.12 AJZ75228.1 - 0.05 13.3 0.1 0.066 12.9 0.1 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SelB-wing_2 PF09106.11 AJZ75228.1 - 0.056 13.7 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF2250 PF10007.9 AJZ75228.1 - 0.06 13.5 0.3 0.13 12.4 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Sulfolobus_pRN PF05584.11 AJZ75228.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein Thiol_cytolysin PF01289.19 AJZ75228.1 - 0.068 12.1 0.0 0.092 11.6 0.0 1.1 1 0 0 1 1 1 0 Thiol-activated cytolysin HTH_Crp_2 PF13545.6 AJZ75228.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DprA_WH PF17782.1 AJZ75228.1 - 0.07 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 DprA winged helix domain DUF1018 PF06252.12 AJZ75228.1 - 0.09 13.8 0.6 0.13 13.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) DUF2615 PF11027.8 AJZ75228.1 - 0.093 12.9 0.3 0.13 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) B-block_TFIIIC PF04182.12 AJZ75228.1 - 0.11 12.7 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Poty_PP PF08440.10 AJZ75228.1 - 0.15 11.1 0.3 0.24 10.4 0.3 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein NYD-SP28 PF14772.6 AJZ75228.1 - 0.61 10.2 6.6 0.37 10.9 0.9 2.1 1 1 1 2 2 2 0 Sperm tail EMC3_TMCO1 PF01956.16 AJZ75228.1 - 0.66 9.7 7.6 0.96 9.2 7.6 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FlaC_arch PF05377.11 AJZ75228.1 - 0.94 9.9 4.1 0.35 11.3 0.3 2.2 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) CoA_binding_2 PF13380.6 AJZ75229.1 - 2.2e-41 141.0 0.3 2.5e-41 140.8 0.3 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 AJZ75229.1 - 4.5e-07 30.5 0.0 8.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain ABC_transp_aux PF09822.9 AJZ75229.1 - 0.037 13.5 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Glyco_hydro_57 PF03065.15 AJZ75229.1 - 0.05 12.8 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 MMR_HSR1_C PF08438.10 AJZ75231.1 - 5.6e-33 113.8 0.1 1.1e-32 112.9 0.1 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 AJZ75231.1 - 2e-20 73.0 0.0 3.1e-19 69.1 0.0 2.3 1 1 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 AJZ75231.1 - 1.1e-08 35.0 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 AJZ75231.1 - 3e-05 23.6 0.2 0.0005 19.6 0.1 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AJZ75231.1 - 0.0012 18.9 0.6 0.47 10.5 0.0 2.8 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 AJZ75231.1 - 0.02 14.4 1.8 1 8.9 0.3 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain tRNA-synt_1e PF01406.19 AJZ75232.1 - 4e-120 400.7 1.2 5.5e-120 400.3 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 AJZ75232.1 - 3.9e-13 48.9 0.2 1.1e-07 30.9 0.2 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 AJZ75232.1 - 4.6e-09 36.6 0.3 1.1e-08 35.4 0.3 1.6 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.22 AJZ75232.1 - 9.5e-08 30.7 0.0 2.6e-06 26.0 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 AJZ75232.1 - 2e-06 27.0 0.4 0.0047 15.9 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (K) NAD_synthase PF02540.17 AJZ75233.1 - 7.2e-77 257.8 0.1 8.5e-77 257.5 0.1 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 AJZ75233.1 - 0.00018 20.4 0.1 0.2 10.4 0.0 2.3 2 0 0 2 2 2 2 tRNA methyl transferase Asn_synthase PF00733.21 AJZ75233.1 - 0.0068 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 AJZ75233.1 - 0.019 14.4 0.0 0.05 13.1 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC HTH_25 PF13413.6 AJZ75233.1 - 0.08 12.8 0.1 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain ATP_bind_3 PF01171.20 AJZ75233.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Rieske PF00355.26 AJZ75234.1 - 6.4e-14 51.7 0.0 7.1e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AJZ75234.1 - 2.1e-10 40.5 0.0 2.6e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain AdoHcyase PF05221.17 AJZ75235.1 - 1e-55 189.0 0.0 1.3e-29 103.3 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AJZ75235.1 - 5e-55 186.0 1.1 5e-55 186.0 1.1 2.1 3 0 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 AJZ75235.1 - 7e-09 35.3 1.0 3.7e-08 32.9 0.4 2.3 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AJZ75235.1 - 5.4e-06 26.1 0.2 1.1e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 AJZ75235.1 - 0.005 16.9 0.2 0.72 9.9 0.1 2.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 AJZ75235.1 - 0.013 14.8 4.9 0.11 11.8 3.9 2.6 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 AJZ75235.1 - 0.03 14.6 0.1 0.094 13.0 0.1 1.9 1 0 0 1 1 1 0 TrkA-N domain tRNA-synt_1g PF09334.11 AJZ75236.1 - 4.1e-138 460.4 0.5 6.1e-138 459.8 0.5 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AJZ75236.1 - 3.2e-15 55.4 0.3 1.3e-05 23.7 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AJZ75236.1 - 3.8e-12 46.2 0.1 1.3e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AJZ75236.1 - 1.5e-06 27.4 0.2 0.0031 16.5 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 AJZ75236.1 - 1.5e-06 28.3 0.1 2.7e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PolC_DP2 PF03833.13 AJZ75236.1 - 0.018 12.9 0.2 0.026 12.4 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 FhuF PF06276.12 AJZ75236.1 - 0.056 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Kp4 PF09044.10 AJZ75236.1 - 0.15 12.2 0.8 0.35 11.0 0.8 1.6 1 0 0 1 1 1 0 Kp4 DZR PF12773.7 AJZ75236.1 - 0.53 10.3 6.8 1 9.4 6.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-Di19 PF05605.12 AJZ75236.1 - 2.4 8.5 5.6 6.5 7.1 5.6 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_2 PF13240.6 AJZ75236.1 - 2.5 8.0 5.7 2.2 8.1 2.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF726 PF05277.12 AJZ75237.1 - 4.5e-11 42.3 0.0 5.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.12 AJZ75237.1 - 1.1e-08 34.9 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.22 AJZ75237.1 - 0.0042 17.1 0.0 0.006 16.6 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF676 PF05057.14 AJZ75237.1 - 0.005 16.4 0.3 0.011 15.3 0.1 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 AJZ75237.1 - 0.01 15.0 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 AJZ75237.1 - 0.011 15.3 0.4 0.025 14.1 0.2 1.5 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 AJZ75237.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 AJZ75237.1 - 0.034 13.4 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Tup_N PF08581.10 AJZ75238.1 - 0.22 11.8 4.0 0.64 10.4 2.3 2.7 1 1 1 2 2 2 0 Tup N-terminal IlvN PF07991.12 AJZ75239.1 - 1.8e-67 226.0 1.2 2.5e-67 225.6 1.2 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 AJZ75239.1 - 8e-56 188.3 2.3 1.2e-55 187.8 2.3 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 AJZ75239.1 - 7.3e-06 25.5 0.1 1.3e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AJZ75239.1 - 9.6e-05 22.6 0.2 0.00036 20.8 0.1 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AJZ75239.1 - 0.00018 22.0 0.2 0.00044 20.8 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 AJZ75239.1 - 0.0081 16.2 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF4897 PF16238.5 AJZ75239.1 - 0.047 13.5 0.9 0.17 11.7 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4897) B12-binding PF02310.19 AJZ75240.1 - 5.3e-20 71.7 0.0 5.9e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 B12 binding domain Ocnus PF05005.15 AJZ75240.1 - 0.0026 17.9 0.0 0.0036 17.4 0.0 1.2 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) IMPDH PF00478.25 AJZ75240.1 - 0.036 13.1 0.0 0.044 12.8 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Peptidase_M1 PF01433.20 AJZ75241.1 - 1.1e-85 286.7 1.4 1.8e-85 286.0 1.4 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 AJZ75241.1 - 5.8e-70 236.3 0.2 6e-69 233.0 0.1 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 AJZ75241.1 - 5.4e-53 179.9 4.7 6e-53 179.8 2.4 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 AJZ75241.1 - 0.0028 17.1 1.5 0.029 13.8 0.2 2.3 2 0 0 2 2 2 1 Putative aminopeptidase Uricase PF01014.18 AJZ75241.1 - 0.053 13.8 0.1 2.5 8.4 0.0 3.3 2 1 0 2 2 2 0 Uricase DUF2808 PF10989.8 AJZ75241.1 - 0.093 12.7 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) MeaB PF03308.16 AJZ75243.1 - 2.7e-71 239.7 6.3 3.3e-71 239.4 6.3 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 AJZ75243.1 - 3e-07 30.2 0.1 6.6e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 AJZ75243.1 - 2e-05 24.5 0.7 0.017 15.0 0.1 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.14 AJZ75243.1 - 0.00013 21.3 3.2 0.00074 18.8 2.7 2.1 1 1 0 1 1 1 1 KAP family P-loop domain RsgA_GTPase PF03193.16 AJZ75243.1 - 0.00017 21.6 1.7 0.014 15.3 0.2 2.5 2 1 0 2 2 2 1 RsgA GTPase DUF190 PF02641.15 AJZ75243.1 - 0.0012 19.2 1.1 5.6 7.4 0.1 3.3 3 0 0 3 3 3 1 Uncharacterized ACR, COG1993 CbiA PF01656.23 AJZ75243.1 - 0.0034 17.4 0.0 0.0077 16.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 AJZ75243.1 - 0.0036 17.0 0.3 0.0066 16.2 0.3 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AJZ75243.1 - 0.0058 16.5 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.22 AJZ75243.1 - 0.0076 15.5 2.6 0.011 15.0 0.2 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 AJZ75243.1 - 0.0091 16.4 0.6 0.023 15.1 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain DUF1154 PF06631.11 AJZ75243.1 - 0.0095 15.9 0.2 0.0095 15.9 0.2 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF1154) ATPase_2 PF01637.18 AJZ75243.1 - 0.019 14.9 1.2 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 AJZ75243.1 - 0.02 15.4 6.3 1.5 9.3 0.5 2.4 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 AJZ75243.1 - 0.021 14.7 0.3 0.063 13.2 0.1 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase MnmE_helical PF12631.7 AJZ75243.1 - 0.023 14.8 0.0 0.033 14.3 0.0 1.3 1 1 0 1 1 1 0 MnmE helical domain PRK PF00485.18 AJZ75243.1 - 0.027 14.2 1.2 0.049 13.4 0.2 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF2007 PF09413.10 AJZ75243.1 - 0.06 13.5 0.0 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein ABC_tran PF00005.27 AJZ75243.1 - 0.067 13.7 3.9 0.12 12.9 0.8 2.4 2 1 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 AJZ75243.1 - 0.069 12.4 0.2 0.15 11.3 0.2 1.6 1 0 0 1 1 1 0 Zeta toxin IIGP PF05049.13 AJZ75243.1 - 0.07 12.2 0.3 0.07 12.2 0.3 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 AJZ75243.1 - 0.1 12.3 0.9 0.25 11.1 0.9 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AJZ75243.1 - 0.14 12.2 5.3 0.93 9.6 5.3 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_binding PF01877.17 AJZ75243.1 - 0.31 11.3 4.0 0.28 11.5 1.9 2.0 2 1 0 2 2 1 0 RNA binding MM_CoA_mutase PF01642.22 AJZ75244.1 - 8.4e-214 710.9 2.3 9.5e-214 710.7 2.3 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase Glyoxalase_4 PF13669.6 AJZ75245.1 - 1.1e-24 86.8 0.0 1.3e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 AJZ75245.1 - 7e-12 45.7 0.0 7.5e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AJZ75245.1 - 1.5e-11 44.7 0.0 1.6e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AJZ75245.1 - 0.011 16.5 0.0 0.014 16.2 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain DUF1338 PF07063.13 AJZ75245.1 - 0.053 12.7 0.0 3.6 6.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1338) WVELL PF14043.6 AJZ75245.1 - 0.11 12.4 0.1 1.5 8.7 0.1 2.1 2 0 0 2 2 2 0 WVELL protein CBS PF00571.28 AJZ75246.1 - 1.1e-17 64.2 1.1 4.1e-10 40.0 0.1 2.2 2 0 0 2 2 2 2 CBS domain HTH_3 PF01381.22 AJZ75246.1 - 3.8e-14 52.5 0.4 7.4e-14 51.6 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 AJZ75246.1 - 3e-08 33.6 0.2 7e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 AJZ75246.1 - 1.1e-07 32.1 0.0 2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AJZ75246.1 - 0.00036 20.3 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AJZ75246.1 - 0.0043 16.5 1.0 0.0091 15.5 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 MqsA_antitoxin PF15731.5 AJZ75246.1 - 0.018 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_Crp_2 PF13545.6 AJZ75246.1 - 0.029 14.3 0.0 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AJZ75246.1 - 0.034 13.7 0.0 0.081 12.5 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_37 PF13744.6 AJZ75246.1 - 0.059 13.3 0.6 0.9 9.5 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 AJZ75246.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein Trp_repressor PF01371.19 AJZ75246.1 - 0.2 11.8 0.5 1.4 9.1 0.1 2.2 1 1 1 2 2 2 0 Trp repressor protein Response_reg PF00072.24 AJZ75247.1 - 5e-14 52.4 0.1 9.8e-14 51.5 0.1 1.5 1 1 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AJZ75247.1 - 0.002 18.5 0.1 0.0053 17.1 0.1 1.6 1 1 0 1 1 1 1 Flagellar regulatory protein FleQ Glyco_hydro_67C PF07477.12 AJZ75247.1 - 0.0033 17.0 0.0 0.0039 16.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Fucose_iso_N1 PF07881.12 AJZ75247.1 - 0.047 13.5 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain PEP-utilizers_C PF02896.18 AJZ75248.1 - 5.7e-83 278.4 0.0 1.1e-82 277.5 0.0 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 AJZ75248.1 - 3.9e-55 187.4 0.0 5e-41 141.0 0.0 3.2 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 AJZ75248.1 - 7.3e-27 92.9 0.6 1.8e-26 91.6 0.6 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain TIM PF00121.18 AJZ75249.1 - 4.2e-06 26.3 0.2 3.8e-05 23.2 0.0 2.0 1 1 1 2 2 2 1 Triosephosphate isomerase ThiG PF05690.14 AJZ75249.1 - 0.00053 19.4 0.4 0.0013 18.2 0.4 1.6 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 AJZ75249.1 - 0.0027 16.8 0.2 0.0043 16.1 0.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Keratin PF02422.16 AJZ75249.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Keratin TrmB PF01978.19 AJZ75250.1 - 1.8e-13 50.1 0.0 3.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AJZ75250.1 - 0.00011 21.7 0.2 0.00021 20.8 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AJZ75250.1 - 0.00012 21.9 0.1 0.00043 20.2 0.1 1.9 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 AJZ75250.1 - 0.00015 21.6 0.3 0.00042 20.2 0.0 1.9 2 0 0 2 2 2 1 MarR family Mig-14 PF07395.11 AJZ75250.1 - 0.00071 19.0 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 2 Mig-14 MarR_2 PF12802.7 AJZ75250.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AJZ75250.1 - 0.019 15.0 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AJZ75250.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 AJZ75250.1 - 0.085 12.7 0.2 0.44 10.4 0.0 2.2 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 AJZ75250.1 - 0.086 13.0 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 AJZ75250.1 - 0.09 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain COG5 PF10392.9 AJZ75250.1 - 0.13 12.4 0.7 0.26 11.4 0.7 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 FlxA PF14282.6 AJZ75250.1 - 0.3 11.1 2.5 0.54 10.3 2.5 1.4 1 0 0 1 1 1 0 FlxA-like protein T2SSF PF00482.23 AJZ75251.1 - 9.6e-17 61.1 0.1 2.5e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F NAPRTase_C PF17956.1 AJZ75251.1 - 0.0021 18.5 0.0 0.0035 17.7 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain T2SSF PF00482.23 AJZ75252.1 - 5.3e-15 55.5 0.3 5.3e-15 55.5 0.3 3.1 3 1 0 3 3 3 1 Type II secretion system (T2SS), protein F DUF2207 PF09972.9 AJZ75252.1 - 0.63 8.7 7.3 1.2 7.8 0.8 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TackOD1 PF18551.1 AJZ75253.1 - 1.2e-26 93.5 2.7 2.3e-26 92.6 2.7 1.5 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 zf-Di19 PF05605.12 AJZ75253.1 - 0.039 14.2 0.5 0.039 14.2 0.5 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 AJZ75253.1 - 0.094 12.8 10.7 3.5 7.8 0.1 3.8 3 1 0 3 3 3 0 Zinc ribbon domain Terminase_GpA PF05876.12 AJZ75253.1 - 0.098 11.2 0.7 0.13 10.8 0.7 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-ribbon_3 PF13248.6 AJZ75253.1 - 0.12 11.9 2.4 2.8 7.5 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 AJZ75253.1 - 0.2 11.4 0.2 0.2 11.4 0.2 3.6 4 0 0 4 4 4 0 InsA N-terminal domain C1_4 PF07975.12 AJZ75253.1 - 0.66 10.2 5.0 4.2 7.7 1.6 2.8 2 0 0 2 2 2 0 TFIIH C1-like domain zinc-ribbons_6 PF07191.12 AJZ75253.1 - 0.71 9.9 9.2 0.55 10.2 3.2 2.5 1 1 2 3 3 3 0 zinc-ribbons zf_UBZ PF18439.1 AJZ75253.1 - 1.2 8.8 6.0 12 5.6 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 AJZ75253.1 - 2.2 8.3 8.0 34 4.5 0.3 3.3 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-H2C2_2 PF13465.6 AJZ75253.1 - 2.3 8.8 6.6 3.7 8.2 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Pilin_N PF07790.11 AJZ75254.1 - 0.0037 18.2 2.5 0.0037 18.2 2.5 2.2 1 1 1 2 2 2 1 Archaeal Type IV pilin, N-terminal DUF11 PF01345.18 AJZ75256.1 - 0.058 13.7 0.2 0.99 9.8 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF11 PPC PF04151.15 AJZ75256.1 - 0.14 13.3 4.1 19 6.4 0.0 3.9 4 0 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain DarA_N PF18788.1 AJZ75257.1 - 0.017 15.2 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 Defence against restriction A N-terminal Big_11 PF18200.1 AJZ75257.1 - 0.13 12.1 6.3 0.96 9.4 0.1 4.0 4 1 1 5 5 5 0 Bacterial Ig-like domain VCBS PF13517.6 AJZ75258.1 - 0.021 15.4 0.2 0.059 14.0 0.2 1.8 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 AJZ75258.1 - 0.039 14.1 0.2 0.089 12.9 0.2 1.6 1 0 0 1 1 1 0 FG-GAP repeat Big_1 PF02369.16 AJZ75259.1 - 0.0025 17.8 0.2 0.0025 17.8 0.2 3.9 4 1 0 4 4 4 1 Bacterial Ig-like domain (group 1) CarboxypepD_reg PF13620.6 AJZ75259.1 - 0.0041 17.4 0.7 0.026 14.8 0.3 2.5 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain U71 PF17474.2 AJZ75259.1 - 0.047 13.6 0.1 1.1 9.3 0.0 2.9 3 0 0 3 3 3 0 Tegument protein UL11 homolog Glyco_hydro2_C5 PF18565.1 AJZ75259.1 - 0.21 11.5 1.9 77 3.2 0.1 4.9 5 0 0 5 5 5 0 Glycoside hydrolase family 2 C-terminal domain 5 DNA_pol_B PF00136.21 AJZ75260.1 - 2.3e-53 181.5 4.6 3.9e-53 180.8 4.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 AJZ75260.1 - 4.8e-41 141.0 4.5 9.7e-41 140.0 4.5 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.6 AJZ75260.1 - 5.5e-07 29.7 0.7 1.6e-06 28.2 0.7 1.7 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 AJZ75260.1 - 0.00011 22.0 0.1 0.00046 19.9 0.0 2.1 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB HI0933_like PF03486.14 AJZ75260.1 - 0.14 10.8 0.0 0.34 9.6 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein Rotamase_3 PF13616.6 AJZ75261.1 - 1.4e-26 93.3 0.0 1.9e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AJZ75261.1 - 2.8e-23 82.7 0.0 3.4e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AJZ75261.1 - 2.8e-09 37.9 0.0 3.3e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Get5_C PF18514.1 AJZ75261.1 - 0.083 12.6 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Get5 C-terminal domain HTH_Tnp_4 PF13613.6 AJZ75261.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Putative_PNPOx PF01243.20 AJZ75262.1 - 2.8e-13 49.8 0.0 3.6e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 AJZ75262.1 - 1.1e-07 31.9 0.0 1.3e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.12 AJZ75262.1 - 0.0059 16.4 0.0 0.0066 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF447) FMN_bind_2 PF04299.12 AJZ75262.1 - 0.075 12.7 0.1 0.29 10.8 0.1 1.8 1 1 0 1 1 1 0 Putative FMN-binding domain Monellin PF09200.10 AJZ75262.1 - 0.19 11.6 3.8 13 5.8 0.1 3.1 2 1 1 3 3 3 0 Monellin PUCC PF03209.15 AJZ75263.1 - 0.021 13.9 0.0 0.022 13.8 0.0 1.0 1 0 0 1 1 1 0 PUCC protein SpoVAB PF13782.6 AJZ75263.1 - 0.023 15.0 0.1 0.029 14.6 0.1 1.3 1 1 0 1 1 1 0 Stage V sporulation protein AB DUF2407_C PF13373.6 AJZ75263.1 - 0.12 12.6 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF2203 PF09969.9 AJZ75264.1 - 6.2e-35 120.6 0.1 7e-35 120.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) HAS-barrel PF09378.10 AJZ75264.1 - 0.093 12.9 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 HAS barrel domain Aldo_ket_red PF00248.21 AJZ75265.1 - 1.1e-24 87.1 0.2 2.8e-20 72.7 0.1 2.3 1 1 1 2 2 2 2 Aldo/keto reductase family DUF321 PF03778.13 AJZ75265.1 - 0.079 12.6 0.8 0.079 12.6 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF321) Arch_flagellin PF01917.16 AJZ75266.1 - 0.00092 19.4 6.0 0.0014 18.8 6.0 1.3 1 1 0 1 1 1 1 Archaebacterial flagellin BMC PF00936.19 AJZ75266.1 - 0.09 12.8 0.9 0.45 10.5 0.0 2.2 2 0 0 2 2 2 0 BMC domain Dus PF01207.17 AJZ75267.1 - 1.4e-71 241.2 0.0 1.6e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NanE PF04131.14 AJZ75267.1 - 0.0002 20.6 0.1 0.00083 18.6 0.0 2.0 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Oxidored_FMN PF00724.20 AJZ75267.1 - 0.0002 20.7 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SOR_SNZ PF01680.17 AJZ75267.1 - 0.0026 17.6 0.3 0.0056 16.5 0.1 1.6 2 0 0 2 2 2 1 SOR/SNZ family YHS PF04945.13 AJZ75268.1 - 7.4e-13 48.4 1.9 8.9e-13 48.1 1.9 1.1 1 0 0 1 1 1 1 YHS domain Arc_trans_TRASH PF08394.10 AJZ75268.1 - 1.7e-06 28.2 2.7 2.3e-06 27.8 2.7 1.2 1 0 0 1 1 1 1 Archaeal TRASH domain ATPase-cat_bd PF12156.8 AJZ75268.1 - 8.8e-05 23.2 0.3 9.9e-05 23.0 0.3 1.1 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase DUF2116 PF09889.9 AJZ75268.1 - 0.56 10.2 4.1 0.65 10.0 2.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Asn_synthase PF00733.21 AJZ75269.1 - 1e-28 101.1 0.0 1.7e-16 60.8 0.0 2.0 1 1 1 2 2 2 2 Asparagine synthase ATP_bind_3 PF01171.20 AJZ75269.1 - 6.9e-05 22.7 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DZR PF12773.7 AJZ75269.1 - 0.00023 21.1 0.3 0.00073 19.5 0.3 1.8 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 AJZ75269.1 - 0.00049 19.7 1.5 0.00049 19.7 1.5 2.1 2 0 0 2 2 2 1 zinc-ribbon domain NAD_synthase PF02540.17 AJZ75269.1 - 0.00079 18.6 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD synthase zinc_ribbon_15 PF17032.5 AJZ75269.1 - 0.00094 19.9 1.1 0.0023 18.6 1.1 1.7 1 0 0 1 1 1 1 zinc-ribbon family tRNA_Me_trans PF03054.16 AJZ75269.1 - 0.004 16.0 0.0 0.0066 15.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 AJZ75269.1 - 0.018 14.5 0.3 0.059 12.9 0.0 2.0 2 1 0 2 2 2 0 Queuosine biosynthesis protein QueC UPF0547 PF10571.9 AJZ75269.1 - 0.031 14.4 0.7 0.087 12.9 0.7 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Couple_hipA PF13657.6 AJZ75269.1 - 0.17 12.5 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 HipA N-terminal domain HTH_3 PF01381.22 AJZ75270.1 - 6.8e-05 22.9 0.0 0.0002 21.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AJZ75270.1 - 0.012 15.6 0.1 0.04 13.9 0.1 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 AJZ75270.1 - 0.03 14.1 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.12 AJZ75270.1 - 0.059 13.3 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 HTH domain Cro PF09048.10 AJZ75270.1 - 0.078 13.0 0.0 0.27 11.3 0.0 1.8 2 1 0 2 2 2 0 Cro YdaS_antitoxin PF15943.5 AJZ75270.1 - 0.084 12.7 0.0 0.96 9.4 0.0 2.3 1 1 1 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT RepB PF07506.11 AJZ75270.1 - 0.091 12.8 0.1 0.72 9.9 0.0 2.2 1 1 2 3 3 3 0 RepB plasmid partitioning protein Alba PF01918.21 AJZ75271.1 - 4.3e-05 23.2 0.0 7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Alba RNA_pol_Rpb6 PF01192.22 AJZ75272.1 - 6.2e-11 42.0 0.0 1.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb6 Turandot PF07240.11 AJZ75272.1 - 0.0015 18.5 0.4 0.0026 17.7 0.4 1.3 1 0 0 1 1 1 1 Stress-inducible humoral factor Turandot DUF465 PF04325.13 AJZ75272.1 - 0.02 15.0 0.3 0.057 13.5 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Cyclophil_like PF04126.13 AJZ75273.1 - 1.1e-12 47.8 0.0 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 AJZ75273.1 - 4.9e-05 23.3 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin-like family Ribosomal_S25 PF03297.15 AJZ75274.1 - 4.5e-07 30.0 4.5 6.3e-07 29.5 4.5 1.2 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 AJZ75274.1 - 8.8e-05 22.0 0.2 0.00013 21.5 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AJZ75274.1 - 0.00025 20.9 0.1 0.00045 20.1 0.1 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AJZ75274.1 - 0.00093 19.0 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF977 PF06163.11 AJZ75274.1 - 0.0012 18.8 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) DUF3489 PF11994.8 AJZ75274.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) HTH_IclR PF09339.10 AJZ75274.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.7 AJZ75274.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 AJZ75274.1 - 0.061 13.3 0.1 0.085 12.8 0.1 1.3 1 0 0 1 1 1 0 HTH domain Phage_int_SAM_6 PF18644.1 AJZ75275.1 - 0.057 13.4 0.7 0.11 12.5 0.6 1.5 1 1 1 2 2 2 0 Phage integrase SAM-like domain Glutaredoxin2_C PF04399.13 AJZ75275.1 - 0.064 13.1 0.7 0.17 11.7 0.3 1.7 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain DUF3450 PF11932.8 AJZ75275.1 - 0.084 12.2 3.9 0.11 11.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TFIID-18kDa PF02269.16 AJZ75275.1 - 0.098 12.7 0.2 0.098 12.7 0.2 1.7 2 1 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit NAD_binding_5 PF07994.12 AJZ75275.1 - 0.12 11.8 0.3 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase RNA_pol_Rpb2_45 PF10385.9 AJZ75275.1 - 0.13 12.6 0.6 8.1 6.8 0.1 2.2 1 1 1 2 2 2 0 RNA polymerase beta subunit external 1 domain Response_reg PF00072.24 AJZ75276.1 - 8.7e-27 93.5 1.7 9.7e-27 93.4 1.7 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CBS PF00571.28 AJZ75277.1 - 9.6e-29 99.6 3.5 3.2e-07 30.7 0.1 4.2 4 0 0 4 4 4 4 CBS domain malic PF00390.19 AJZ75277.1 - 0.024 14.4 1.7 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain RE_HaeII PF09554.10 AJZ75277.1 - 0.028 13.7 0.1 0.094 12.0 0.0 1.9 2 1 0 2 2 2 0 HaeII restriction endonuclease Limkain-b1 PF11608.8 AJZ75277.1 - 0.088 12.9 0.0 0.26 11.4 0.0 1.8 1 1 1 2 2 2 0 Limkain b1 Clr5 PF14420.6 AJZ75277.1 - 0.23 11.7 1.2 6.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Clr5 domain tRNA-Thr_ED PF08915.11 AJZ75280.1 - 1.2e-43 148.5 0.2 2.6e-43 147.4 0.2 1.6 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase HGTP_anticodon PF03129.20 AJZ75280.1 - 1.3e-22 79.7 0.5 3e-22 78.6 0.5 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AJZ75280.1 - 1.6e-15 57.5 0.1 3.1e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Arginase PF00491.21 AJZ75281.1 - 2.5e-70 237.2 0.1 2.8e-70 237.0 0.1 1.0 1 0 0 1 1 1 1 Arginase family CDP-OH_P_transf PF01066.21 AJZ75282.1 - 3.3e-10 40.6 0.2 3.3e-10 40.6 0.2 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ThrE PF06738.12 AJZ75282.1 - 0.064 12.6 0.5 0.064 12.6 0.5 2.4 2 1 0 2 2 2 0 Putative threonine/serine exporter DUF4131 PF13567.6 AJZ75282.1 - 5.8 6.5 6.9 0.84 9.3 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_S26e PF01283.19 AJZ75283.1 - 4.4e-22 78.6 0.4 5.3e-22 78.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Lar_restr_allev PF14354.6 AJZ75283.1 - 0.086 13.2 0.3 0.32 11.4 0.1 1.9 1 1 1 2 2 2 0 Restriction alleviation protein Lar ADD_ATRX PF17981.1 AJZ75283.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.5 2 0 0 2 2 2 0 Cysteine Rich ADD domain zinc_ribbon_2 PF13240.6 AJZ75283.1 - 0.14 11.9 0.7 0.14 11.9 0.7 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Guanylate_cyc PF00211.20 AJZ75284.1 - 1.6e-17 63.8 0.2 2.5e-17 63.1 0.2 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HAMP PF00672.25 AJZ75284.1 - 1.9e-15 57.0 0.0 3.5e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 HAMP domain dCache_1 PF02743.18 AJZ75284.1 - 7.5e-10 39.0 3.9 1.2e-09 38.3 1.2 2.2 2 0 0 2 2 2 1 Cache domain PABP PF00658.18 AJZ75284.1 - 0.023 14.9 0.2 0.49 10.6 0.0 3.0 3 0 0 3 3 3 0 Poly-adenylate binding protein, unique domain PfkB PF00294.24 AJZ75285.1 - 6.3e-09 35.6 0.0 2e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase NAD_kinase PF01513.21 AJZ75286.1 - 9.6e-30 103.8 0.3 1.3e-29 103.4 0.3 1.2 1 0 0 1 1 1 1 ATP-NAD kinase HTH_24 PF13412.6 AJZ75286.1 - 0.00019 20.9 0.0 0.0005 19.6 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AJZ75286.1 - 0.0012 18.7 0.2 0.0027 17.5 0.2 1.6 2 0 0 2 2 2 1 MarR family MarR PF01047.22 AJZ75286.1 - 0.0016 18.3 1.3 0.0022 17.9 0.4 1.7 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 AJZ75286.1 - 0.0033 17.3 0.3 0.016 15.0 0.2 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 AJZ75286.1 - 0.0084 16.6 0.2 0.022 15.2 0.2 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain RNA_pol_Rpc34 PF05158.12 AJZ75286.1 - 0.015 14.7 0.2 0.023 14.1 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit CTP_synth_N PF06418.14 AJZ75287.1 - 1.7e-115 384.9 0.9 2.4e-115 384.4 0.9 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 AJZ75287.1 - 4.3e-50 170.1 0.0 7.2e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJZ75287.1 - 1.5e-11 44.4 0.0 3.5e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 AJZ75287.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 AJZ75287.1 - 0.032 13.4 0.0 0.063 12.4 0.0 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase PQ-loop PF04193.14 AJZ75288.1 - 1.3e-09 37.7 3.4 1.3e-09 37.7 3.4 1.4 2 0 0 2 2 2 1 PQ loop repeat MtN3_slv PF03083.16 AJZ75288.1 - 1.6e-08 34.5 4.3 1.8e-08 34.3 4.3 1.0 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange LAB_N PF07578.11 AJZ75288.1 - 1e-05 25.5 1.4 1.3e-05 25.2 1.4 1.1 1 0 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain Imp-YgjV PF10688.9 AJZ75288.1 - 0.2 11.5 8.0 0.78 9.5 8.0 1.8 1 1 0 1 1 1 0 Bacterial inner membrane protein DUF3040 PF11239.8 AJZ75288.1 - 0.29 11.5 1.7 0.44 10.9 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Chordopox_A13L PF05961.11 AJZ75288.1 - 0.92 9.8 3.9 1.5 9.2 3.9 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Trp_syntA PF00290.20 AJZ75289.1 - 4.7e-86 287.8 0.7 5.2e-86 287.7 0.7 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain DHO_dh PF01180.21 AJZ75289.1 - 5e-07 29.2 0.7 6.9e-07 28.8 0.7 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 AJZ75289.1 - 5.1e-06 26.1 0.2 1.4e-05 24.6 0.1 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 AJZ75289.1 - 0.0048 16.3 0.1 0.0069 15.8 0.1 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family FMN_dh PF01070.18 AJZ75289.1 - 0.0061 15.6 0.0 0.018 14.1 0.0 1.7 1 1 1 2 2 2 1 FMN-dependent dehydrogenase IGPS PF00218.21 AJZ75289.1 - 0.019 14.2 0.0 0.082 12.1 0.0 1.8 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase NanE PF04131.14 AJZ75289.1 - 0.026 13.7 0.1 0.053 12.7 0.1 1.7 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Pterin_bind PF00809.22 AJZ75289.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Pterin binding enzyme PALP PF00291.25 AJZ75290.1 - 6.2e-46 157.1 1.0 7.3e-46 156.9 1.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IGPS PF00218.21 AJZ75291.1 - 7.6e-69 231.7 0.8 8.9e-69 231.5 0.8 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.19 AJZ75291.1 - 0.0009 19.1 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Cellulase PF00150.18 AJZ75291.1 - 0.015 14.7 0.1 0.023 14.1 0.1 1.4 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 AJZ75291.1 - 0.057 12.9 0.0 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Glycos_transf_3 PF00591.21 AJZ75292.1 - 3e-82 276.0 1.3 3e-82 276.0 1.3 1.5 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AJZ75292.1 - 3.3e-07 30.1 3.9 4.8e-07 29.5 0.8 2.3 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain HisG_C PF08029.11 AJZ75292.1 - 0.15 12.2 0.1 5.7 7.2 0.0 2.5 2 0 0 2 2 2 0 HisG, C-terminal domain GATase PF00117.28 AJZ75293.1 - 6.8e-53 179.3 0.1 7.6e-53 179.1 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJZ75293.1 - 6.4e-09 35.9 0.2 1.4e-08 34.8 0.2 1.5 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AJZ75293.1 - 0.00039 20.3 0.1 0.00069 19.5 0.1 1.6 1 1 0 1 1 1 1 SNO glutamine amidotransferase family YPEB PF14620.6 AJZ75293.1 - 0.12 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 YpeB sporulation DUF4956 PF16316.5 AJZ75295.1 - 0.06 13.0 0.1 0.071 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) ABM PF03992.16 AJZ75296.1 - 1e-09 38.4 0.4 1.2e-09 38.2 0.4 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3291 PF11695.8 AJZ75296.1 - 0.0086 15.8 0.0 0.012 15.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3291) ILVD_EDD PF00920.21 AJZ75297.1 - 1.3e-211 703.8 2.5 1.4e-211 703.6 2.5 1.0 1 0 0 1 1 1 1 Dehydratase family HIT PF01230.23 AJZ75298.1 - 1.2e-24 86.9 0.3 1.6e-24 86.5 0.3 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AJZ75298.1 - 2.5e-14 53.7 0.1 3e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 AJZ75298.1 - 0.0038 17.1 1.0 0.0073 16.2 1.0 1.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CdiI_4 PF18624.1 AJZ75298.1 - 0.066 13.7 0.1 0.095 13.2 0.1 1.3 1 0 0 1 1 1 0 CDI immunity protein HrpB7 PF09486.10 AJZ75299.1 - 0.032 14.6 0.6 0.4 11.1 0.1 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF899 PF05988.12 AJZ75299.1 - 0.032 13.8 0.3 0.067 12.7 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) GNAT_acetyltran PF12746.7 AJZ75299.1 - 0.089 12.3 3.3 0.11 12.0 3.3 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase PulG PF11773.8 AJZ75299.1 - 0.15 11.9 2.8 0.19 11.6 0.4 2.0 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin DUF1664 PF07889.12 AJZ75299.1 - 2.6 8.1 10.5 4.9 7.2 3.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 AJZ75299.1 - 4.8 7.9 13.3 8.5 7.1 3.9 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 AJZ75299.1 - 8.6 5.3 13.3 2.3 7.2 10.2 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Response_reg PF00072.24 AJZ75300.1 - 5.1e-16 58.8 0.2 3.1e-15 56.3 0.2 2.0 1 1 0 1 1 1 1 Response regulator receiver domain HYR PF02494.16 AJZ75301.1 - 2.7e-14 53.3 20.2 5.7e-08 33.0 3.3 4.4 4 1 1 5 5 5 2 HYR domain HYR PF02494.16 AJZ75302.1 - 1.3e-17 63.9 8.4 5.1e-09 36.3 0.6 3.0 2 0 0 2 2 2 2 HYR domain TSP_3 PF02412.18 AJZ75302.1 - 1.5e-05 24.6 16.5 0.00043 19.9 4.6 2.6 2 0 0 2 2 2 2 Thrombospondin type 3 repeat Big_1 PF02369.16 AJZ75302.1 - 0.62 10.1 8.6 0.15 12.1 2.5 3.2 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 1) LIM_bind PF01803.16 AJZ75302.1 - 1.3 8.5 0.0 1.3 8.5 0.0 3.3 4 1 1 5 5 5 0 LIM-domain binding protein MetOD1 PF18546.1 AJZ75302.1 - 5.7 6.9 7.2 6.3 6.8 0.9 2.5 2 0 0 2 2 2 0 Metanogen output domain 1 Cullin_Nedd8 PF10557.9 AJZ75304.1 - 0.1 12.7 0.3 0.68 10.0 0.0 2.0 2 0 0 2 2 2 0 Cullin protein neddylation domain Mnd1 PF03962.15 AJZ75304.1 - 0.11 12.8 0.0 0.64 10.3 0.0 2.0 2 0 0 2 2 2 0 Mnd1 HTH domain Thioredoxin_4 PF13462.6 AJZ75305.1 - 2.7e-32 112.2 0.0 3.5e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AJZ75305.1 - 1.4e-13 51.1 0.2 2.1e-12 47.2 0.2 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJZ75305.1 - 8.6e-09 35.8 0.1 1.7e-08 34.9 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 AJZ75305.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF309 PF03745.14 AJZ75305.1 - 0.13 12.0 0.5 0.24 11.1 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF309) DUF4443 PF14544.6 AJZ75306.1 - 0.0018 18.5 0.0 0.0031 17.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4443) ANT PF03374.14 AJZ75306.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain CbtA PF09490.10 AJZ75307.1 - 5.8e-46 157.2 8.3 6.6e-46 157.1 8.3 1.0 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) INSIG PF07281.12 AJZ75307.1 - 0.18 11.4 1.8 1.2 8.7 0.0 2.3 3 0 0 3 3 3 0 Insulin-induced protein (INSIG) TMEM237 PF15383.6 AJZ75307.1 - 0.28 10.3 1.7 0.85 8.7 0.0 2.5 3 1 0 3 3 3 0 Transmembrane protein 237 7TMR-DISM_7TM PF07695.11 AJZ75307.1 - 2.6 7.9 14.7 0.047 13.6 7.5 1.7 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF2628 PF10947.8 AJZ75307.1 - 3.1 8.2 6.3 0.42 11.0 0.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2628) LapA_dom PF06305.11 AJZ75307.1 - 3.1 7.7 0.0 3.1 7.7 0.0 4.0 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain HTH_20 PF12840.7 AJZ75308.1 - 2.8e-06 27.3 0.1 4.3e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AJZ75308.1 - 0.00012 21.9 0.1 0.00029 20.6 0.1 1.7 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 AJZ75308.1 - 0.0014 18.4 0.1 0.0017 18.2 0.1 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit DUF742 PF05331.11 AJZ75308.1 - 0.0063 16.3 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_7 PF02796.15 AJZ75308.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_5 PF01022.20 AJZ75308.1 - 0.019 14.8 0.0 0.041 13.8 0.0 1.6 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 AJZ75308.1 - 0.019 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_11 PF08279.12 AJZ75308.1 - 0.038 13.9 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 HTH domain PadR PF03551.14 AJZ75308.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family EutK_C PF16365.5 AJZ75308.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus Mga PF05043.13 AJZ75308.1 - 0.11 13.0 0.1 1 10.0 0.0 2.1 2 0 0 2 2 2 0 Mga helix-turn-helix domain TrmB PF01978.19 AJZ75309.1 - 0.00025 20.9 0.0 0.00041 20.2 0.0 1.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB FUR PF01475.19 AJZ75309.1 - 0.00061 19.9 0.1 0.00083 19.5 0.1 1.4 1 1 0 1 1 1 1 Ferric uptake regulator family Antigen_Bd37 PF11641.8 AJZ75309.1 - 0.002 17.7 0.1 0.0027 17.2 0.1 1.2 1 0 0 1 1 1 1 Glycosylphosphatidylinositol-anchored merozoite surface protein DUF2250 PF10007.9 AJZ75309.1 - 0.026 14.6 0.1 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_Crp_2 PF13545.6 AJZ75309.1 - 0.031 14.3 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF1492 PF07374.11 AJZ75309.1 - 0.031 14.4 1.0 0.044 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) HTH_20 PF12840.7 AJZ75309.1 - 0.031 14.3 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 AJZ75309.1 - 0.043 13.8 0.1 0.079 12.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PadR PF03551.14 AJZ75309.1 - 0.07 13.1 0.0 0.3 11.1 0.0 1.9 1 1 1 2 2 2 0 Transcriptional regulator PadR-like family Rrf2 PF02082.20 AJZ75309.1 - 0.079 13.3 0.1 0.13 12.7 0.1 1.4 1 1 0 1 1 1 0 Transcriptional regulator HTH_IclR PF09339.10 AJZ75309.1 - 0.21 11.4 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain FTR1 PF03239.14 AJZ75310.1 - 2.1e-19 69.8 20.4 1.4e-18 67.1 18.8 2.6 2 1 0 2 2 2 1 Iron permease FTR1 family Methyltransf_34 PF11312.8 AJZ75310.1 - 0.022 14.0 0.6 1.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase Phage_holin_8 PF16931.5 AJZ75310.1 - 0.093 12.7 3.3 0.22 11.5 3.3 1.6 1 0 0 1 1 1 0 Putative phage holin Hydantoinase_A PF01968.18 AJZ75311.1 - 3.9e-57 193.7 4.9 3.9e-57 193.7 4.9 2.9 3 1 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 AJZ75311.1 - 1.7e-21 76.7 9.0 2.6e-20 72.9 5.7 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region FGGY_N PF00370.21 AJZ75311.1 - 8.7e-05 22.2 2.3 0.00024 20.8 2.3 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 AJZ75311.1 - 0.00013 21.6 2.0 0.00049 19.7 0.8 2.6 2 1 1 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family SIT PF15330.6 AJZ75312.1 - 0.049 14.1 0.0 0.049 14.1 0.0 1.1 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Dicty_CAD PF05720.12 AJZ75312.1 - 0.053 13.5 0.0 0.055 13.5 0.0 1.1 1 0 0 1 1 1 0 Cell-cell adhesion domain Big_9 PF17963.1 AJZ75313.1 - 6.6e-38 129.3 55.7 6.1e-21 75.0 17.8 4.7 4 1 0 4 4 4 3 Bacterial Ig domain Cadherin_4 PF17803.1 AJZ75313.1 - 8.3e-25 87.2 55.6 9.6e-14 51.8 15.0 5.2 4 1 0 4 4 4 3 Bacterial cadherin-like domain Cadherin_5 PF17892.1 AJZ75313.1 - 1.7e-20 72.8 30.8 4.4e-13 49.0 9.0 4.2 4 1 0 4 4 4 2 Cadherin-like domain Cu-binding_MopE PF11617.8 AJZ75313.1 - 0.0047 17.1 4.1 0.0047 17.1 4.1 2.2 2 0 0 2 2 2 1 Putative metal-binding motif Cadherin_3 PF16184.5 AJZ75313.1 - 0.97 9.5 6.7 1.8 8.6 0.2 3.5 3 1 0 3 3 3 0 Cadherin-like DUF1297 PF06973.12 AJZ75314.1 - 2.2e-72 242.5 0.0 2.9e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.12 AJZ75314.1 - 1.2e-42 144.8 0.0 2.8e-42 143.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1246) HTH_5 PF01022.20 AJZ75316.1 - 8.1e-09 35.2 0.1 1.5e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AJZ75316.1 - 1.6e-05 24.4 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AJZ75316.1 - 2.2e-05 24.4 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AJZ75316.1 - 0.00067 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB RepL PF05732.11 AJZ75316.1 - 0.0062 16.0 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) TFIIE_alpha PF02002.17 AJZ75316.1 - 0.0065 16.3 0.1 0.01 15.7 0.1 1.2 1 0 0 1 1 1 1 TFIIE alpha subunit Sigma70_r4 PF04545.16 AJZ75316.1 - 0.028 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_11 PF08279.12 AJZ75316.1 - 0.045 13.7 0.1 0.098 12.6 0.1 1.5 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.7 AJZ75316.1 - 0.047 13.6 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_41 PF14502.6 AJZ75316.1 - 0.2 11.3 0.5 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain SIMPL PF04402.14 AJZ75317.1 - 6.8e-47 160.5 2.2 8.9e-47 160.1 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF3025 PF11227.8 AJZ75317.1 - 0.13 12.1 0.1 0.32 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3025) Pyr_redox_2 PF07992.14 AJZ75320.1 - 6.8e-45 153.5 0.0 8.2e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJZ75320.1 - 7e-11 42.5 0.5 1.5e-07 31.9 0.3 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AJZ75320.1 - 0.0003 20.5 0.1 1.1 8.8 0.0 3.8 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AJZ75320.1 - 0.0045 17.0 0.0 0.13 12.3 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding tRNA-synt_2 PF00152.20 AJZ75321.1 - 7.4e-80 268.4 0.0 9.1e-80 268.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AJZ75321.1 - 2.4e-11 43.4 0.0 4.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AJZ75321.1 - 0.0047 16.4 0.1 0.26 10.7 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) Glu-tRNAGln PF02686.15 AJZ75322.1 - 0.00015 21.9 0.3 0.00037 20.7 0.2 1.6 1 1 1 2 2 2 1 Glu-tRNAGln amidotransferase C subunit Amidase PF01425.21 AJZ75323.1 - 1.7e-140 469.0 0.0 1.9e-140 468.8 0.0 1.0 1 0 0 1 1 1 1 Amidase PTE PF02126.18 AJZ75323.1 - 0.024 14.1 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family RDM PF11002.8 AJZ75323.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 RFPL defining motif (RDM) GatB_N PF02934.15 AJZ75324.1 - 1.8e-92 309.6 0.1 1e-91 307.1 0.0 1.9 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 AJZ75324.1 - 6.8e-32 110.4 3.7 1.1e-31 109.7 3.7 1.4 1 0 0 1 1 1 1 GatB domain DUF1892 PF08987.10 AJZ75324.1 - 0.027 14.7 0.3 0.053 13.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) BrnT_toxin PF04365.13 AJZ75324.1 - 0.04 14.2 0.2 0.54 10.6 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system SPC22 PF04573.12 AJZ75325.1 - 0.088 12.3 0.4 0.16 11.4 0.4 1.4 1 0 0 1 1 1 0 Signal peptidase subunit DUF4006 PF13179.6 AJZ75325.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Saccharop_dh_N PF04455.12 AJZ75326.1 - 4e-35 120.2 0.2 9.1e-35 119.1 0.2 1.6 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region DS PF01916.17 AJZ75326.1 - 0.029 13.6 0.3 0.28 10.4 0.1 2.4 1 1 2 3 3 3 0 Deoxyhypusine synthase Citrate_bind PF16114.5 AJZ75326.1 - 0.044 13.3 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding AnfO_nitrog PF09582.10 AJZ75327.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.3 1 1 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DPBB_1 PF03330.18 AJZ75328.1 - 0.042 14.1 0.0 0.072 13.4 0.0 1.4 1 1 0 1 1 1 0 Lytic transglycolase Cob_adeno_trans PF01923.18 AJZ75329.1 - 1.2e-54 184.9 0.0 1.3e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Glyoxalase PF00903.25 AJZ75330.1 - 4.1e-09 36.7 0.0 5.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AJZ75330.1 - 0.0036 18.1 0.0 0.023 15.5 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain TPR_8 PF13181.6 AJZ75330.1 - 0.04 14.1 0.1 0.08 13.2 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat PTPS PF01242.19 AJZ75331.1 - 0.056 13.4 0.1 0.075 13.0 0.1 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase AsnC_trans_reg PF01037.21 AJZ75332.1 - 1.6e-08 34.4 0.0 1.8e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain ACT_4 PF13291.6 AJZ75332.1 - 0.011 16.3 0.1 0.019 15.5 0.0 1.5 1 1 1 2 2 2 0 ACT domain Glyoxalase PF00903.25 AJZ75333.1 - 1.6e-11 44.5 0.0 2.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AJZ75333.1 - 5.1e-08 32.9 0.0 6.5e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AJZ75333.1 - 6.5e-05 23.2 0.0 0.00053 20.2 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AJZ75333.1 - 8.6e-05 23.3 0.0 0.00011 22.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain DUF507 PF04368.13 AJZ75335.1 - 0.014 15.3 8.8 0.014 15.3 8.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF507) PALP PF00291.25 AJZ75336.1 - 1.3e-83 280.9 0.7 1.8e-83 280.3 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT_4 PF13291.6 AJZ75336.1 - 6.8e-05 23.4 0.3 0.00018 22.0 0.3 1.7 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 AJZ75336.1 - 0.0048 16.6 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 ACT domain RusA PF05866.11 AJZ75336.1 - 0.017 15.7 0.3 0.033 14.7 0.3 1.4 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA AIRC PF00731.20 AJZ75337.1 - 1.8e-60 202.8 0.3 2.3e-60 202.5 0.3 1.1 1 0 0 1 1 1 1 AIR carboxylase PrpR_N PF06506.11 AJZ75337.1 - 0.035 13.7 0.1 0.085 12.4 0.1 1.7 1 1 0 1 1 1 0 Propionate catabolism activator ATP-grasp PF02222.22 AJZ75338.1 - 1.6e-59 200.3 0.2 2.3e-59 199.8 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 AJZ75338.1 - 1.2e-13 50.5 0.0 2.8e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AJZ75338.1 - 3.5e-07 30.0 0.2 9e-07 28.6 0.2 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 AJZ75338.1 - 0.0063 16.1 0.1 0.018 14.6 0.1 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain DUF1297 PF06973.12 AJZ75338.1 - 0.034 13.7 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) GARS_A PF01071.19 AJZ75338.1 - 0.077 12.7 0.3 0.17 11.6 0.1 1.7 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pyr_redox_2 PF07992.14 AJZ75338.1 - 0.079 12.2 0.0 0.83 8.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrmB PF01978.19 AJZ75339.1 - 2.4e-12 46.5 0.0 6.2e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 AJZ75339.1 - 4.3e-05 23.3 0.0 9.4e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AJZ75339.1 - 0.00046 20.0 0.0 0.00097 19.0 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AJZ75339.1 - 0.00094 19.2 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 AJZ75339.1 - 0.019 14.9 0.3 0.57 10.2 0.0 2.3 2 0 0 2 2 2 0 HTH domain HTH_24 PF13412.6 AJZ75339.1 - 0.033 13.7 0.5 0.52 9.9 0.1 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AJZ75339.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain UPA_2 PF17809.1 AJZ75339.1 - 0.04 13.8 0.2 0.18 11.6 0.0 2.0 3 0 0 3 3 3 0 UPA domain CD20 PF04103.15 AJZ75340.1 - 0.12 12.4 0.5 0.12 12.4 0.5 1.7 2 0 0 2 2 2 0 CD20-like family DUF3188 PF11384.8 AJZ75340.1 - 1.4 8.7 8.9 0.45 10.3 1.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) DUF981 PF06168.11 AJZ75340.1 - 2.7 7.9 8.6 0.46 10.4 2.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF981) DUF202 PF02656.15 AJZ75340.1 - 6.5 7.3 7.1 11 6.6 4.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) SNARE_assoc PF09335.11 AJZ75341.1 - 8.9e-20 71.4 5.3 8.9e-20 71.4 5.3 1.9 1 1 1 2 2 2 1 SNARE associated Golgi protein NTP_transferase PF00483.23 AJZ75342.1 - 6.7e-29 101.2 0.0 1.4e-28 100.2 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AJZ75342.1 - 6.5e-13 49.4 0.0 8.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AJZ75342.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase UBA_4 PF14555.6 AJZ75342.1 - 0.22 11.4 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain Bac_luciferase PF00296.20 AJZ75343.1 - 2.4e-59 201.3 0.0 2.8e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Thiolase_C PF02803.18 AJZ75344.1 - 1.2e-13 50.8 0.1 3.4e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 AJZ75344.1 - 1.3e-09 37.8 0.7 3.2e-09 36.5 0.2 2.0 2 1 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 AJZ75344.1 - 9.1e-05 22.2 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AJZ75344.1 - 0.0023 17.8 0.0 0.0059 16.4 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SspH PF08141.12 AJZ75344.1 - 0.028 14.5 0.1 0.36 11.0 0.0 2.5 2 0 0 2 2 2 0 Small acid-soluble spore protein H family Ketoacyl-synt_C PF02801.22 AJZ75344.1 - 0.064 13.3 0.2 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF4859 PF16151.5 AJZ75344.1 - 0.1 12.5 0.1 7.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4859) DUF35_N PF12172.8 AJZ75345.1 - 1e-08 34.9 0.4 3.2e-08 33.3 0.2 1.8 2 0 0 2 2 2 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF1272 PF06906.11 AJZ75345.1 - 0.0024 17.9 1.0 0.0041 17.2 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) Hjc PF01870.18 AJZ75346.1 - 0.0028 17.6 0.0 0.0073 16.3 0.0 1.7 2 0 0 2 2 2 1 Archaeal holliday junction resolvase (hjc) R-HINP1I PF11463.8 AJZ75346.1 - 0.052 13.0 0.2 0.077 12.4 0.2 1.3 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease ANAPC4_WD40 PF12894.7 AJZ75346.1 - 0.09 13.1 0.1 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SesA PF17107.5 AJZ75347.1 - 0.012 15.7 0.9 0.014 15.6 0.9 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases GIT1_C PF12205.8 AJZ75347.1 - 0.029 14.5 0.3 0.049 13.8 0.3 1.4 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Phage_TAC_3 PF06896.11 AJZ75347.1 - 0.038 14.6 1.2 0.057 14.0 1.2 1.5 1 1 0 1 1 1 0 Phage tail assembly chaperone proteins, TAC FlxA PF14282.6 AJZ75347.1 - 0.06 13.3 1.7 0.37 10.8 0.2 2.0 2 0 0 2 2 2 0 FlxA-like protein XPA_N PF01286.18 AJZ75348.1 - 0.037 14.1 1.6 0.038 14.0 0.1 1.8 2 0 0 2 2 2 0 XPA protein N-terminal Cation_efflux PF01545.21 AJZ75350.1 - 8.6e-31 107.2 16.6 1.2e-30 106.8 16.6 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AJZ75350.1 - 0.0017 18.5 2.5 0.0031 17.6 2.5 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF2976 PF11190.8 AJZ75350.1 - 6.4 6.7 9.6 2 8.3 4.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) DapB_N PF01113.20 AJZ75351.1 - 0.0019 18.3 0.0 0.0048 17.0 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 AJZ75351.1 - 0.002 18.4 0.3 0.01 16.2 0.1 2.3 3 1 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 AJZ75351.1 - 0.0093 16.4 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF682 PF05081.12 AJZ75351.1 - 0.039 13.7 0.1 0.068 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF682) IlvN PF07991.12 AJZ75351.1 - 0.049 13.2 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Thioredoxin_4 PF13462.6 AJZ75353.1 - 2.6e-37 128.6 0.5 3.4e-37 128.2 0.1 1.4 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.20 AJZ75353.1 - 9.4e-18 64.7 0.4 1.5e-16 60.7 0.4 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJZ75353.1 - 2e-08 34.7 0.8 1e-07 32.3 0.8 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 AJZ75353.1 - 0.0024 17.6 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin CxxCxxCC PF03692.15 AJZ75354.1 - 4.5e-09 36.9 5.2 4.1e-08 33.8 3.7 2.3 1 1 1 2 2 2 2 Putative zinc- or iron-chelating domain HMG_CoA_synt_C PF08540.10 AJZ75355.1 - 1.2e-33 117.0 0.2 1.7e-33 116.5 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 AJZ75355.1 - 9.9e-31 106.9 0.2 1.5e-30 106.3 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal putAbiC PF16872.5 AJZ75356.1 - 0.087 13.5 0.4 0.17 12.6 0.4 1.6 1 0 0 1 1 1 0 Putative phage abortive infection protein ubiquitin PF00240.23 AJZ75356.1 - 0.11 12.3 1.0 1.2 9.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin family NolB PF17398.2 AJZ75356.1 - 0.13 12.7 0.1 0.31 11.4 0.0 1.6 2 0 0 2 2 2 0 Nodulation protein NolB AAA_26 PF13500.6 AJZ75357.1 - 6e-40 137.2 0.0 6.8e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AJZ75357.1 - 4.1e-06 26.9 0.0 8.6e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AJZ75357.1 - 0.022 14.2 0.7 0.57 9.6 0.2 2.1 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase NTPase_1 PF03266.15 AJZ75357.1 - 0.072 13.0 0.1 0.8 9.6 0.0 2.2 2 0 0 2 2 2 0 NTPase MobB PF03205.14 AJZ75357.1 - 0.12 12.3 0.9 1.4 8.8 0.1 2.8 2 2 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1611 PF07755.11 AJZ75357.1 - 0.15 11.3 0.7 1.2 8.4 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain Aminotran_3 PF00202.21 AJZ75358.1 - 1.8e-93 313.4 0.4 2e-93 313.3 0.4 1.0 1 0 0 1 1 1 1 Aminotransferase class-III WcbI PF18588.1 AJZ75358.1 - 0.021 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI Beta_elim_lyase PF01212.21 AJZ75358.1 - 0.022 14.0 0.1 0.061 12.6 0.1 1.9 1 1 0 1 1 1 0 Beta-eliminating lyase Radical_SAM PF04055.21 AJZ75359.1 - 3.2e-17 63.4 0.2 7.6e-17 62.2 0.1 1.6 2 0 0 2 2 2 1 Radical SAM superfamily BATS PF06968.13 AJZ75359.1 - 6.2e-10 39.1 0.0 1.6e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Aminotran_1_2 PF00155.21 AJZ75360.1 - 4.6e-52 177.4 0.0 5.3e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AJZ75360.1 - 5.9e-06 25.8 0.0 8.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AJZ75360.1 - 0.00091 17.9 0.0 0.0013 17.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 AJZ75360.1 - 0.049 12.2 0.1 0.33 9.5 0.0 2.0 2 0 0 2 2 2 0 Serine hydroxymethyltransferase Thioredoxin_10 PF17991.1 AJZ75361.1 - 1.8e-36 125.8 0.0 2.7e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin like C-terminal domain AhpC-TSA PF00578.21 AJZ75361.1 - 1.7e-07 31.2 0.1 3e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJZ75361.1 - 5.2e-07 29.5 0.0 9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 AJZ75361.1 - 0.00048 20.4 0.1 0.00092 19.5 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like PspC PF04024.12 AJZ75361.1 - 0.01 15.6 0.7 0.17 11.7 0.3 2.4 2 0 0 2 2 2 0 PspC domain Thioredoxin PF00085.20 AJZ75361.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin LRR_10 PF18805.1 AJZ75361.1 - 0.69 9.6 3.5 7 6.4 0.1 3.1 3 0 0 3 3 3 0 Leucine-rich repeat Snf7 PF03357.21 AJZ75362.1 - 0.28 10.8 7.0 0.6 9.7 7.0 1.7 1 1 0 1 1 1 0 Snf7 NOP19 PF10863.8 AJZ75363.1 - 0.01 15.7 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 0 Nucleolar protein 19 WbqC PF08889.11 AJZ75363.1 - 0.044 13.7 0.5 0.058 13.3 0.5 1.3 1 0 0 1 1 1 0 WbqC-like protein family HMD PF03201.16 AJZ75364.1 - 0.024 14.8 0.1 0.041 14.1 0.1 1.3 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PKK PF12474.8 AJZ75364.1 - 0.035 14.2 1.3 0.062 13.4 1.3 1.5 1 1 0 1 1 1 0 Polo kinase kinase DUF4799 PF16056.5 AJZ75364.1 - 0.065 12.4 0.0 0.079 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) KMP11 PF03037.16 AJZ75364.1 - 0.075 13.8 1.9 1 10.2 0.2 2.3 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 DUF1456 PF07308.13 AJZ75366.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) FANCI_HD1 PF14679.6 AJZ75366.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 1 0 1 1 1 0 FANCI helical domain 1 Conotoxin PF02950.17 AJZ75366.1 - 0.15 13.1 0.0 0.2 12.7 0.0 1.2 1 0 0 1 1 1 0 Conotoxin FANCI_HD1 PF14679.6 AJZ75367.1 - 0.09 12.7 0.2 0.11 12.4 0.2 1.4 1 1 0 1 1 1 0 FANCI helical domain 1 DUF4577 PF15145.6 AJZ75368.1 - 0.023 14.7 0.6 0.034 14.2 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF4668 PF15701.5 AJZ75368.1 - 6.2 6.6 7.6 1.9 8.3 2.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4668) DZR PF12773.7 AJZ75369.1 - 0.0032 17.4 0.3 0.0041 17.1 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-LYAR PF08790.11 AJZ75369.1 - 0.035 14.0 0.8 7.8 6.5 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF35_N PF12172.8 AJZ75369.1 - 0.036 13.9 1.4 1.1 9.2 0.0 2.5 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-IS66 PF13005.7 AJZ75369.1 - 0.046 14.1 4.4 0.36 11.3 0.2 2.8 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 C1_4 PF07975.12 AJZ75369.1 - 0.054 13.7 2.0 2.9 8.2 2.7 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_4 PF13894.6 AJZ75369.1 - 0.18 12.7 0.7 5 8.2 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_L6 PF00347.23 AJZ75370.1 - 9.7e-12 45.4 5.3 1.4e-05 25.6 0.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S14 PF00253.21 AJZ75371.1 - 4.8e-09 35.8 2.9 5.9e-09 35.5 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-FPG_IleRS PF06827.14 AJZ75371.1 - 0.026 14.4 3.1 0.026 14.4 3.1 1.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Ribosomal_L5_C PF00673.21 AJZ75372.1 - 5.9e-23 80.9 0.0 1.3e-22 79.8 0.0 1.6 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AJZ75372.1 - 3e-15 56.3 0.3 6.1e-15 55.3 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_S4e PF00900.20 AJZ75373.1 - 8.5e-19 67.2 0.3 1.7e-18 66.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 AJZ75373.1 - 5.4e-11 42.4 1.0 1e-10 41.6 1.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 AJZ75373.1 - 8e-05 22.3 0.1 0.00037 20.1 0.1 2.1 2 0 0 2 2 2 1 S4 domain Ribosomal_L26 PF16906.5 AJZ75374.1 - 2.7e-17 63.0 0.2 4.5e-17 62.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 AJZ75374.1 - 2.5e-05 24.0 0.5 2.5e-05 24.0 0.5 1.8 2 0 0 2 2 2 1 KOW motif Trypan_PARP PF05887.11 AJZ75374.1 - 0.38 10.7 9.3 0.67 9.9 9.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_L14 PF00238.19 AJZ75375.1 - 6.7e-33 113.4 0.3 7.8e-33 113.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_S17 PF00366.20 AJZ75376.1 - 4.5e-17 61.9 2.2 5.9e-17 61.5 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 G2F PF07474.12 AJZ75376.1 - 0.081 12.7 0.2 0.095 12.5 0.2 1.1 1 0 0 1 1 1 0 G2F domain UPF0086 PF01868.16 AJZ75377.1 - 5.2e-18 64.7 0.1 6.2e-18 64.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_L29 PF00831.23 AJZ75378.1 - 2e-11 43.7 6.5 2.7e-11 43.3 6.5 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein Vps5 PF09325.10 AJZ75378.1 - 0.018 14.6 2.0 0.018 14.6 2.0 1.1 1 0 0 1 1 1 0 Vps5 C terminal like Snapin_Pallidin PF14712.6 AJZ75378.1 - 0.13 12.7 4.6 0.15 12.5 4.6 1.2 1 0 0 1 1 1 0 Snapin/Pallidin Ribosomal_S3_C PF00189.20 AJZ75379.1 - 2.8e-20 72.6 0.5 6.8e-20 71.4 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AJZ75379.1 - 6.9e-15 54.6 0.2 6.9e-15 54.6 0.2 2.8 3 0 0 3 3 3 1 KH domain KH_4 PF13083.6 AJZ75379.1 - 0.063 13.2 0.1 0.25 11.2 0.1 2.0 1 0 0 1 1 1 0 KH domain Ribosomal_L22 PF00237.19 AJZ75380.1 - 1.6e-25 89.3 0.9 2.1e-25 88.9 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S19 PF00203.21 AJZ75381.1 - 8.4e-26 89.7 0.7 1.1e-25 89.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L23 PF00276.20 AJZ75382.1 - 6.3e-13 48.9 0.9 9.8e-13 48.3 0.9 1.3 1 1 0 1 1 1 1 Ribosomal protein L23 DNA_mis_repair PF01119.19 AJZ75382.1 - 0.03 14.0 0.1 0.042 13.5 0.0 1.3 1 1 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain RRM_1 PF00076.22 AJZ75382.1 - 0.08 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L4 PF00573.22 AJZ75383.1 - 6e-40 137.0 0.2 7.1e-40 136.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L3 PF00297.22 AJZ75384.1 - 8.8e-73 245.4 1.6 7e-72 242.4 1.6 1.9 1 1 0 1 1 1 1 Ribosomal protein L3 Methyltrn_RNA_3 PF02598.17 AJZ75385.1 - 1.1e-52 179.3 0.0 1.3e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 AJZ75385.1 - 5.9e-05 23.3 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family DUF371 PF04027.13 AJZ75386.1 - 4.2e-45 153.0 0.0 4.6e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF371) HTH_20 PF12840.7 AJZ75387.1 - 6.3e-10 39.0 0.1 1e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AJZ75387.1 - 1.9e-06 27.6 0.2 1.3e-05 24.9 0.2 2.1 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family FUR PF01475.19 AJZ75387.1 - 0.00029 21.0 1.1 0.00068 19.8 1.1 1.7 1 1 0 1 1 1 1 Ferric uptake regulator family HTH_12 PF08461.10 AJZ75387.1 - 0.0013 18.6 0.4 0.0045 16.9 0.3 1.9 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain Type2_restr_D3 PF16902.5 AJZ75387.1 - 0.011 15.6 0.5 0.021 14.7 0.5 1.5 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain HTH_11 PF08279.12 AJZ75387.1 - 0.015 15.2 1.5 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 HTH domain Replic_Relax PF13814.6 AJZ75387.1 - 0.017 15.2 0.1 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 Replication-relaxation HU-DNA_bdg PF14848.6 AJZ75387.1 - 0.023 14.7 3.1 2.2 8.3 0.2 2.2 2 0 0 2 2 2 0 DNA-binding domain TFIIE_alpha PF02002.17 AJZ75387.1 - 0.024 14.5 0.6 0.42 10.5 0.2 2.2 1 1 1 2 2 2 0 TFIIE alpha subunit DUF2513 PF10711.9 AJZ75387.1 - 0.073 13.4 0.4 0.17 12.2 0.2 1.7 1 1 0 1 1 1 0 Hypothetical protein (DUF2513) SAICAR_synt PF01259.18 AJZ75388.1 - 4.8e-71 239.3 0.1 5.8e-71 239.1 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase DUF3146 PF11344.8 AJZ75388.1 - 0.02 14.6 0.0 0.073 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) PMT_2 PF13231.6 AJZ75389.1 - 2.3e-13 50.7 16.0 2.3e-13 50.7 16.0 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Glyco_transf_22 PF03901.17 AJZ75389.1 - 0.00057 19.2 23.9 0.11 11.6 23.9 2.1 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Peptidase_M50B PF13398.6 AJZ75389.1 - 0.59 9.7 22.9 1.8 8.2 3.6 3.1 2 1 1 3 3 3 0 Peptidase M50B-like DUF4352 PF11611.8 AJZ75391.1 - 0.029 14.6 0.1 0.096 13.0 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4352) DUF5300 PF17224.3 AJZ75391.1 - 0.046 14.0 0.0 0.067 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) Big_1 PF02369.16 AJZ75391.1 - 0.077 13.0 0.7 4.7 7.3 0.0 2.3 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 1) AsnC_trans_reg PF01037.21 AJZ75392.1 - 2.3e-12 46.7 0.2 2.8e-12 46.4 0.2 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 AJZ75392.1 - 0.0015 18.5 0.1 0.0018 18.3 0.1 1.1 1 0 0 1 1 1 1 NapD protein EF1_GNE PF00736.19 AJZ75392.1 - 0.016 15.3 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain DUF585 PF04522.12 AJZ75392.1 - 0.037 13.6 0.3 0.041 13.5 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF585) GATase_6 PF13522.6 AJZ75393.1 - 5.1e-13 49.4 0.0 4.6e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AJZ75393.1 - 2.4e-12 46.9 0.0 6.6e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 AJZ75393.1 - 2.3e-09 37.0 0.0 4.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 AJZ75393.1 - 3.9e-06 26.0 0.0 7.5e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Dip PF17679.1 AJZ75393.1 - 0.0006 19.5 0.1 0.049 13.2 0.0 2.9 3 0 0 3 3 3 1 gp37/Dip protein GATase_2 PF00310.21 AJZ75393.1 - 0.0014 17.4 0.1 0.058 12.1 0.0 2.7 3 1 0 3 3 3 1 Glutamine amidotransferases class-II DUF3700 PF12481.8 AJZ75393.1 - 0.0034 16.8 0.0 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Aluminium induced protein AIRS_C PF02769.22 AJZ75394.1 - 3.5e-50 170.2 2.8 7.6e-30 104.1 0.4 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AJZ75394.1 - 3.2e-41 139.9 0.1 4e-19 69.0 0.2 2.6 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain FGAR-AT_linker PF18072.1 AJZ75394.1 - 2.1e-11 44.2 0.3 5e-11 43.0 0.3 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Chordopox_RPO7 PF05864.12 AJZ75394.1 - 0.099 12.9 0.7 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) GATase_5 PF13507.6 AJZ75395.1 - 4.3e-41 140.7 0.0 1.3e-40 139.2 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 AJZ75395.1 - 4.2e-09 36.3 0.0 9.2e-09 35.2 0.0 1.5 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 AJZ75395.1 - 4e-08 33.3 0.0 1.8e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 AJZ75395.1 - 1.1e-07 31.8 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 AJZ75395.1 - 0.0046 16.7 0.1 0.01 15.6 0.1 1.6 1 1 0 1 1 1 1 Peptidase C26 CBS PF00571.28 AJZ75396.1 - 7.1e-27 93.6 1.2 1.6e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 CBS domain TatC PF00902.18 AJZ75398.1 - 1.8e-48 165.1 17.4 2.2e-48 164.9 17.4 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF4519 PF15012.6 AJZ75398.1 - 0.12 12.6 1.1 3.1 8.0 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) MttA_Hcf106 PF02416.16 AJZ75399.1 - 1e-09 37.6 0.4 1.2e-09 37.3 0.4 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family Polyketide_cyc PF03364.20 AJZ75400.1 - 0.0078 16.4 0.0 0.0089 16.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF5612 PF18462.1 AJZ75400.1 - 0.017 14.9 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) Flavoprotein PF02441.19 AJZ75401.1 - 9.1e-26 90.5 0.1 1.1e-25 90.2 0.1 1.0 1 0 0 1 1 1 1 Flavoprotein Bt_P21 PF05560.11 AJZ75401.1 - 0.043 13.4 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Big_9 PF17963.1 AJZ75402.1 - 1.9e-181 589.4 188.6 2.1e-22 79.7 2.5 12.3 13 0 0 13 13 13 10 Bacterial Ig domain Cadherin_5 PF17892.1 AJZ75402.1 - 5.7e-119 388.6 106.5 6.8e-16 58.0 1.1 10.7 10 0 0 10 10 10 10 Cadherin-like domain Cadherin_4 PF17803.1 AJZ75402.1 - 6.4e-115 375.9 184.3 6.8e-17 61.9 1.5 13.6 13 1 0 13 13 13 10 Bacterial cadherin-like domain HemolysinCabind PF00353.19 AJZ75402.1 - 1.7e-31 107.7 94.8 6.7e-10 38.8 17.2 5.7 1 1 4 5 5 5 5 RTX calcium-binding nonapeptide repeat (4 copies) Calx-beta PF03160.14 AJZ75402.1 - 1.5e-10 41.1 1.0 1.5e-09 37.9 0.0 3.1 2 0 0 2 2 2 1 Calx-beta domain Cadherin_3 PF16184.5 AJZ75402.1 - 1.6e-05 24.8 33.5 0.019 14.9 0.0 8.9 9 0 0 9 9 9 2 Cadherin-like DUF1325 PF07039.11 AJZ75402.1 - 0.14 12.2 0.3 14 5.8 0.1 3.0 2 0 0 2 2 2 0 SGF29 tudor-like domain Phage_tail_T PF06223.12 AJZ75402.1 - 0.21 12.1 0.1 0.8 10.3 0.1 2.0 1 0 0 1 1 1 0 Minor tail protein T DUF1297 PF06973.12 AJZ75403.1 - 9e-73 243.8 0.1 1.4e-72 243.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.12 AJZ75403.1 - 2e-45 153.7 0.0 4e-45 152.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) DNase-RNase PF02577.14 AJZ75404.1 - 3.4e-08 33.2 0.0 3.7e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease Skp1_POZ PF03931.15 AJZ75404.1 - 0.13 12.5 0.8 4.7 7.5 0.8 2.2 1 1 0 1 1 1 0 Skp1 family, tetramerisation domain DUF4060 PF13269.6 AJZ75404.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4060) PHD_like PF12910.7 AJZ75405.1 - 0.00074 19.6 0.0 0.00086 19.4 0.0 1.1 1 0 0 1 1 1 1 Antitoxin of toxin-antitoxin, RelE / RelB, TA system HicB_lk_antitox PF15919.5 AJZ75405.1 - 0.0012 18.9 0.0 0.0012 18.9 0.0 1.1 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 AJZ75406.1 - 1.8e-10 40.7 0.0 2.2e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, ISK_Channel PF02060.15 AJZ75407.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Slow voltage-gated potassium channel DUF5615 PF18480.1 AJZ75409.1 - 2.7e-06 27.0 0.1 3.9e-06 26.5 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5615) Mut7-C PF01927.16 AJZ75409.1 - 0.0016 18.6 0.0 0.0017 18.5 0.0 1.1 1 0 0 1 1 1 1 Mut7-C RNAse domain IPT PF01745.16 AJZ75410.1 - 0.0021 17.5 0.1 0.0033 16.9 0.1 1.3 1 0 0 1 1 1 1 Isopentenyl transferase DUF460 PF04312.13 AJZ75410.1 - 0.044 13.5 1.4 0.11 12.2 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF460) Methyltransf_3 PF01596.17 AJZ75411.1 - 1.5e-28 99.4 0.4 2e-28 99.1 0.4 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 AJZ75411.1 - 1.1e-14 55.3 0.0 1.6e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJZ75411.1 - 5.9e-05 22.9 0.0 8.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJZ75411.1 - 0.00048 20.8 0.0 0.0009 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 AJZ75411.1 - 0.001 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_15 PF09445.10 AJZ75411.1 - 0.0096 15.5 0.0 0.023 14.3 0.0 1.6 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase TylF PF05711.11 AJZ75411.1 - 0.03 13.6 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Cons_hypoth95 PF03602.15 AJZ75411.1 - 0.1 12.2 0.3 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein 95 PCMT PF01135.19 AJZ75411.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 AJZ75411.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) WES_acyltransf PF03007.16 AJZ75412.1 - 9.9 5.8 9.6 1.1 9.0 4.1 2.1 1 1 1 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain CPDase PF07823.11 AJZ75413.1 - 4.9e-10 39.4 0.6 3.1e-07 30.3 0.6 3.0 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein SPACA9 PF15120.6 AJZ75413.1 - 0.016 15.0 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 Toprim_Crpt PF13342.6 AJZ75413.1 - 0.032 14.2 0.5 0.37 10.8 0.1 2.7 2 1 0 2 2 2 0 C-terminal repeat of topoisomerase 2_5_RNA_ligase2 PF13563.6 AJZ75413.1 - 0.038 13.9 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily DUF4437 PF14499.6 AJZ75414.1 - 0.0029 16.8 0.0 0.0029 16.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) DUF1971 PF09313.11 AJZ75414.1 - 0.047 13.7 0.1 0.073 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) PMSR PF01625.21 AJZ75415.1 - 4.1e-66 221.9 0.7 4.9e-66 221.6 0.7 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Cmc1 PF08583.10 AJZ75417.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Peptidase_M10 PF00413.24 AJZ75418.1 - 1.2e-11 44.7 0.0 2.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 AJZ75418.1 - 0.00037 20.2 0.0 0.00089 18.9 0.0 1.6 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Reprolysin_5 PF13688.6 AJZ75418.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.24 AJZ75418.1 - 0.044 13.4 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 AJZ75418.1 - 0.078 13.5 0.1 0.5 10.9 0.0 2.2 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Cupin_2 PF07883.11 AJZ75420.1 - 2.5e-07 30.3 0.0 1.3e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 AJZ75420.1 - 3.7e-06 26.6 0.0 4.9e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Cupin Auxin_BP PF02041.16 AJZ75420.1 - 0.00082 19.1 0.1 0.00098 18.8 0.1 1.2 1 0 0 1 1 1 1 Auxin binding protein AraC_binding PF02311.19 AJZ75420.1 - 0.0027 17.6 0.0 0.0069 16.3 0.0 1.7 1 1 0 1 1 1 1 AraC-like ligand binding domain Ribosomal_S17 PF00366.20 AJZ75420.1 - 0.0045 17.1 3.2 0.047 13.8 0.1 2.5 1 1 1 2 2 2 1 Ribosomal protein S17 Cupin_8 PF13621.6 AJZ75420.1 - 0.021 14.5 0.1 0.03 14.0 0.1 1.4 1 1 0 1 1 1 0 Cupin-like domain Cupin_4 PF08007.12 AJZ75420.1 - 0.021 14.3 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 Cupin superfamily protein Proteasom_Rpn13 PF04683.13 AJZ75420.1 - 0.063 13.8 0.1 0.23 12.0 0.0 1.9 1 1 1 2 2 2 0 Proteasome complex subunit Rpn13 ubiquitin receptor zf-C3HC4_4 PF15227.6 AJZ75421.1 - 0.0046 17.1 2.8 0.032 14.4 0.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 AJZ75421.1 - 0.018 14.9 1.5 0.68 9.9 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AJZ75421.1 - 0.043 13.8 2.4 1.7 8.7 0.2 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 AJZ75421.1 - 0.077 13.0 2.6 6.9 6.7 0.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C2HCIx2C PF10782.9 AJZ75424.1 - 0.029 14.3 0.9 0.029 14.3 0.9 2.1 2 0 0 2 2 2 0 Zinc-finger GTP_EFTU PF00009.27 AJZ75426.1 - 1.3e-55 187.9 0.1 2.1e-55 187.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AJZ75426.1 - 1.5e-23 82.8 0.1 2.6e-22 78.8 0.0 2.4 1 1 1 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 AJZ75426.1 - 2.7e-21 75.4 0.0 8.1e-21 73.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AJZ75426.1 - 2.3e-18 66.1 0.1 5.4e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 AJZ75426.1 - 5.1e-13 49.2 0.0 1.6e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AJZ75426.1 - 0.0098 16.0 0.1 0.022 14.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DDE_Tnp_1_assoc PF13808.6 AJZ75426.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-associated SIS PF01380.22 AJZ75427.1 - 7.9e-10 38.7 0.6 6.5e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.6 AJZ75427.1 - 0.017 15.2 0.1 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 SIS domain CBS PF00571.28 AJZ75428.1 - 1.2e-30 105.8 3.0 1.5e-10 41.4 0.2 4.2 4 0 0 4 4 4 4 CBS domain RTP PF02334.16 AJZ75428.1 - 0.055 14.1 0.1 0.19 12.4 0.0 1.9 2 0 0 2 2 2 0 Replication terminator protein VitK2_biosynth PF02621.14 AJZ75429.1 - 4.9e-75 252.5 0.0 5.5e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis Thiamine_BP PF01910.17 AJZ75430.1 - 2.4e-24 85.1 0.1 2.6e-24 84.9 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Radical_SAM PF04055.21 AJZ75431.1 - 3.8e-18 66.4 0.0 9.8e-18 65.1 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 AJZ75431.1 - 0.0083 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain BKACE PF05853.12 AJZ75431.1 - 0.044 13.1 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 beta-keto acid cleavage enzyme Fer4_12 PF13353.6 AJZ75431.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF3584 PF12128.8 AJZ75433.1 - 1.1 6.6 47.3 1.5 6.3 47.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1189 PF06691.11 AJZ75433.1 - 3 7.3 9.4 12 5.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) Apolipoprotein PF01442.18 AJZ75434.1 - 0.0026 17.6 17.5 0.0038 17.1 17.5 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATF7IP_BD PF16788.5 AJZ75434.1 - 0.0059 16.7 15.4 0.0059 16.7 15.4 1.5 1 1 1 2 2 2 1 ATF-interacting protein binding domain Asp-B-Hydro_N PF05279.11 AJZ75434.1 - 0.12 12.4 22.2 0.15 12.1 22.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LMBR1 PF04791.16 AJZ75434.1 - 1.4 7.8 6.4 1.6 7.5 6.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Stathmin PF00836.19 AJZ75434.1 - 2.1 8.3 30.8 0.35 10.8 17.0 2.1 1 1 1 2 2 2 0 Stathmin family ARGLU PF15346.6 AJZ75434.1 - 2.6 7.9 30.5 14 5.5 14.0 2.2 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 Ntox15 PF15604.6 AJZ75434.1 - 3.1 7.9 16.5 2 8.5 13.5 2.0 1 1 1 2 2 2 0 Novel toxin 15 TPR_1 PF00515.28 AJZ75435.1 - 7.6e-19 66.7 3.3 3.4e-07 29.8 1.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 AJZ75435.1 - 2.9e-16 58.2 1.4 5.4e-05 23.0 0.4 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 AJZ75435.1 - 5.2e-12 45.5 0.0 0.026 15.3 0.0 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 AJZ75435.1 - 7.1e-12 45.7 0.1 0.00024 21.6 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJZ75435.1 - 1.3e-10 41.2 1.0 0.071 13.2 0.0 4.2 3 1 1 4 4 4 3 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 AJZ75435.1 - 6.7e-10 38.7 4.5 4e-06 26.8 0.4 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AJZ75435.1 - 8e-10 39.2 0.0 3.1e-06 27.7 0.0 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AJZ75435.1 - 2.1e-08 33.6 0.2 0.04 14.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AJZ75435.1 - 4e-08 33.4 1.7 0.00045 20.5 0.9 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AJZ75435.1 - 1.1e-07 31.4 2.4 4.8e-05 23.0 0.2 3.9 2 2 1 3 3 3 1 TPR repeat TPR_6 PF13174.6 AJZ75435.1 - 2.1e-06 28.0 0.1 1.5 9.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 AJZ75435.1 - 5.9e-06 26.1 2.9 0.0038 17.3 0.5 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 AJZ75435.1 - 0.0004 20.1 0.3 0.07 13.0 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AJZ75435.1 - 0.00044 20.4 3.0 0.039 14.2 0.2 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 AJZ75435.1 - 0.002 18.2 0.0 0.71 10.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AJZ75435.1 - 0.0083 16.6 0.4 3.7 8.0 0.1 2.9 1 1 2 3 3 3 1 Alkyl sulfatase dimerisation MRP_L53 PF10780.9 AJZ75435.1 - 0.041 14.1 0.1 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 M11L PF11099.8 AJZ75435.1 - 0.051 13.9 2.0 0.071 13.4 0.6 1.9 1 1 1 2 2 2 0 Apoptosis regulator M11L like Malic_M PF03949.15 AJZ75437.1 - 3.4e-24 85.5 6.2 2.4e-23 82.8 6.2 2.2 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 AJZ75437.1 - 3.5e-22 79.1 0.3 1.3e-19 70.7 0.3 2.6 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain AdoHcyase_NAD PF00670.21 AJZ75437.1 - 0.00021 21.4 2.8 0.003 17.6 1.1 2.7 2 1 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.21 AJZ75437.1 - 0.00082 18.8 0.5 0.0015 17.9 0.5 1.4 1 0 0 1 1 1 1 ThiF family Phage_int_SAM_3 PF14659.6 AJZ75437.1 - 0.002 18.4 1.7 1.8 8.9 0.1 3.5 3 0 0 3 3 3 2 Phage integrase, N-terminal SAM-like domain Shikimate_DH PF01488.20 AJZ75437.1 - 0.004 17.2 0.1 0.0094 16.0 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 AJZ75437.1 - 0.0096 15.7 0.7 0.02 14.6 0.7 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FAD_binding_3 PF01494.19 AJZ75437.1 - 0.2 10.8 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TPR_1 PF00515.28 AJZ75438.1 - 2.5e-21 74.5 0.2 1.1e-12 47.1 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 AJZ75438.1 - 9.4e-20 69.1 0.2 2e-10 40.0 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 AJZ75438.1 - 2.4e-13 49.5 0.2 3.9e-07 29.7 0.0 2.1 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 AJZ75438.1 - 3.4e-13 48.7 0.0 1.8e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 AJZ75438.1 - 4.1e-13 49.7 0.1 4.9e-13 49.5 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 AJZ75438.1 - 5.3e-12 46.1 0.1 6e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 AJZ75438.1 - 5.9e-12 45.3 0.2 3.2e-05 24.4 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 AJZ75438.1 - 6.6e-12 44.6 0.3 1.1e-05 25.1 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 AJZ75438.1 - 1.6e-10 41.2 0.0 1.2e-05 25.5 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 AJZ75438.1 - 2.2e-09 37.4 0.1 2.5e-09 37.2 0.1 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 AJZ75438.1 - 1.5e-08 34.4 0.2 3.2e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJZ75438.1 - 2.2e-06 27.6 0.0 0.064 13.3 0.0 2.1 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 AJZ75438.1 - 4.9e-06 26.2 0.3 0.012 15.5 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 AJZ75438.1 - 1.7e-05 25.2 0.1 0.063 13.9 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat NARP1 PF12569.8 AJZ75438.1 - 0.00033 19.7 0.0 0.00039 19.5 0.0 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_3 PF07720.12 AJZ75438.1 - 0.00049 20.0 0.1 0.19 11.8 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 AJZ75438.1 - 0.001 19.2 0.0 0.0016 18.5 0.0 1.4 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) BTAD PF03704.17 AJZ75438.1 - 0.0019 18.6 0.0 0.0022 18.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial transcriptional activator domain MIT PF04212.18 AJZ75438.1 - 0.0024 17.9 0.1 2.3 8.3 0.0 2.1 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 AJZ75438.1 - 0.0025 18.0 0.0 0.0029 17.8 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 AJZ75438.1 - 0.0033 16.7 0.0 0.32 10.2 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat PPR PF01535.20 AJZ75438.1 - 0.0063 16.7 0.1 2.4 8.6 0.0 2.4 2 1 0 2 2 2 1 PPR repeat EST1_DNA_bind PF10373.9 AJZ75438.1 - 0.011 15.2 0.0 0.012 15.2 0.0 1.0 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain TOM20_plant PF06552.12 AJZ75438.1 - 0.015 15.1 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 SHNi-TPR PF10516.9 AJZ75438.1 - 0.031 13.7 0.4 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 SHNi-TPR DUF5113 PF17140.4 AJZ75438.1 - 0.047 13.5 0.0 3 7.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5113) DUF4649 PF15507.6 AJZ75438.1 - 0.056 13.4 0.0 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4649) MAS20 PF02064.15 AJZ75438.1 - 0.064 13.4 0.0 6.8 6.8 0.0 2.0 1 1 1 2 2 2 0 MAS20 protein import receptor Response_reg PF00072.24 AJZ75439.1 - 1.8e-13 50.6 0.0 4.4e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 Response regulator receiver domain BRCT_3 PF18428.1 AJZ75439.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.6 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain AsnC_trans_reg PF01037.21 AJZ75440.1 - 1.1e-12 47.7 0.1 1.7e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AJZ75440.1 - 6.4e-11 41.6 1.4 1.2e-10 40.7 1.4 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AJZ75440.1 - 7.7e-11 41.6 0.5 1.2e-10 41.1 0.5 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 AJZ75440.1 - 0.00051 19.9 0.3 0.0013 18.6 0.3 1.9 1 0 0 1 1 1 1 HTH domain HTH_50 PF18024.1 AJZ75440.1 - 0.0012 18.4 0.1 0.0036 16.9 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AJZ75440.1 - 0.0014 18.5 0.3 0.0029 17.5 0.3 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MazG-like PF12643.7 AJZ75440.1 - 0.043 14.1 1.3 5.5 7.3 0.2 2.4 2 0 0 2 2 2 0 MazG-like family ADH_zinc_N PF00107.26 AJZ75440.1 - 0.11 12.5 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MarR PF01047.22 AJZ75440.1 - 0.11 12.4 0.7 0.17 11.8 0.3 1.5 2 0 0 2 2 2 0 MarR family HD PF01966.22 AJZ75441.1 - 0.0016 18.7 0.2 0.0035 17.5 0.0 1.6 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 AJZ75441.1 - 0.0049 16.6 0.1 0.0093 15.7 0.1 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PHM7_cyt PF14703.6 AJZ75441.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF5413 PF17434.2 AJZ75441.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5413) Sugar_tr PF00083.24 AJZ75442.1 - 9.1e-33 113.8 35.4 1.7e-26 93.1 8.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AJZ75442.1 - 1.4e-32 113.0 37.8 1.4e-32 113.0 37.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 AJZ75442.1 - 4.3e-07 28.8 11.0 4.3e-07 28.8 11.0 2.3 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_5 PF05631.14 AJZ75442.1 - 3.6e-05 22.8 0.8 3.6e-05 22.8 0.8 2.6 1 1 2 3 3 3 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 AJZ75442.1 - 7.6e-05 21.7 2.0 7.6e-05 21.7 2.0 3.0 2 2 1 3 3 3 2 MFS_1 like family PAC2 PF09754.9 AJZ75444.1 - 2.2e-23 83.4 0.0 2.6e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 PAC2 family CarboxypepD_reg PF13620.6 AJZ75446.1 - 3.2e-07 30.5 0.9 6e-07 29.6 0.9 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 AJZ75446.1 - 0.0048 16.9 0.2 0.015 15.3 0.2 1.9 1 0 0 1 1 1 1 CarboxypepD_reg-like domain Big_1 PF02369.16 AJZ75446.1 - 0.072 13.1 0.7 0.34 11.0 0.4 2.2 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) Titin_Ig-rpts PF06582.12 AJZ75448.1 - 3.9 7.5 4.7 0.49 10.4 0.6 1.7 2 0 0 2 2 2 0 Titin repeat S4 PF01479.25 AJZ75449.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 S4 domain DUF1177 PF06675.11 AJZ75449.1 - 0.19 10.5 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) HTH_45 PF14947.6 AJZ75450.1 - 0.0054 16.7 0.0 0.0079 16.2 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_34 PF13601.6 AJZ75450.1 - 0.0067 16.6 0.0 0.009 16.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain PadR PF03551.14 AJZ75450.1 - 0.0081 16.1 0.0 0.0094 15.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family TrmB PF01978.19 AJZ75450.1 - 0.037 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HxlR PF01638.17 AJZ75450.1 - 0.13 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Voltage_CLC PF00654.20 AJZ75451.1 - 0.058 12.6 0.1 0.092 12.0 0.1 1.3 1 0 0 1 1 1 0 Voltage gated chloride channel Nucleoside_tran PF01733.18 AJZ75451.1 - 0.11 11.8 0.6 0.64 9.3 0.1 1.9 1 1 0 2 2 2 0 Nucleoside transporter PIN PF01850.21 AJZ75452.1 - 2.2e-10 41.1 0.0 3.3e-10 40.5 0.0 1.3 1 1 0 1 1 1 1 PIN domain PIN_4 PF13638.6 AJZ75452.1 - 1.6e-05 25.2 0.0 4.8e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 PIN domain PIN_12 PF16289.5 AJZ75452.1 - 0.00061 20.3 0.1 0.00079 20.0 0.1 1.3 1 1 0 1 1 1 1 PIN domain DUF5615 PF18480.1 AJZ75452.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) PIN_3 PF13470.6 AJZ75452.1 - 0.18 12.6 0.0 0.3 11.9 0.0 1.5 1 1 0 1 1 1 0 PIN domain Response_reg PF00072.24 AJZ75453.1 - 0.0013 18.9 0.1 0.0019 18.4 0.1 1.2 1 1 0 1 1 1 1 Response regulator receiver domain DUF695 PF05117.12 AJZ75453.1 - 0.1 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF695) BPD_transp_1 PF00528.22 AJZ75454.1 - 2.1e-35 122.1 17.6 2.1e-35 122.1 17.6 2.0 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component DUF3481 PF11980.8 AJZ75454.1 - 0.092 12.5 2.9 4.7 7.0 0.1 2.5 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein PalH PF08733.10 AJZ75454.1 - 3.6 6.5 7.9 0.45 9.5 3.4 1.7 2 0 0 2 2 2 0 PalH/RIM21 BPD_transp_1 PF00528.22 AJZ75455.1 - 5.8e-26 91.4 6.9 5.8e-26 91.4 6.9 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Phage_int_SAM_4 PF13495.6 AJZ75456.1 - 0.044 14.3 0.7 0.2 12.1 0.2 1.9 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain Muted PF14942.6 AJZ75457.1 - 0.061 13.7 32.3 1.1 9.7 8.9 3.7 2 1 0 3 3 3 0 Organelle biogenesis, Muted-like protein Glu-tRNAGln PF02686.15 AJZ75457.1 - 0.089 13.1 1.4 1.4 9.3 0.1 3.1 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit GlutR_N PF05201.15 AJZ75457.1 - 0.17 11.7 6.1 0.13 12.0 1.2 2.9 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, N-terminal domain Cas6b_C PF17262.2 AJZ75457.1 - 0.19 11.8 3.0 8.7 6.5 0.3 3.1 2 0 0 2 2 2 0 Cas6b C-terminal domain Baculo_PEP_C PF04513.12 AJZ75457.1 - 0.27 11.3 13.7 0.75 9.8 0.5 4.4 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ACP_PD PF04336.12 AJZ75457.1 - 0.91 10.0 6.7 31 5.0 0.3 4.2 3 2 0 4 4 4 0 Acyl carrier protein phosphodiesterase SLATT_6 PF18169.1 AJZ75457.1 - 1.5 8.4 15.5 0.15 11.6 3.0 3.1 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 STAT_alpha PF01017.20 AJZ75457.1 - 2.4 8.0 25.8 1.4 8.8 6.8 3.4 3 0 0 3 3 3 0 STAT protein, all-alpha domain NPV_P10 PF05531.12 AJZ75457.1 - 2.8 8.5 25.9 9.1 6.8 2.4 5.9 4 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 AJZ75457.1 - 3 6.7 35.1 0.11 11.4 6.8 3.3 3 0 0 3 3 3 0 Spc7 kinetochore protein Dus PF01207.17 AJZ75457.1 - 3.1 6.8 6.8 0.71 8.9 2.1 2.1 2 1 1 3 3 3 0 Dihydrouridine synthase (Dus) MCPsignal PF00015.21 AJZ75457.1 - 4.9 6.9 24.7 0.52 10.1 3.5 4.4 2 2 1 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Polyketide_cyc2 PF10604.9 AJZ75458.1 - 4.7e-10 39.9 0.0 6.1e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polysacc_deac_1 PF01522.21 AJZ75459.1 - 1.2e-23 83.4 0.0 1.5e-10 41.0 0.0 2.6 2 0 0 2 2 2 2 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 AJZ75459.1 - 1.7e-08 34.1 0.1 1.8e-05 24.1 0.0 3.0 3 1 0 3 3 3 2 Glycosyl hydrolase family 57 DUF2334 PF10096.9 AJZ75459.1 - 5.1e-06 26.3 9.1 0.00018 21.2 0.6 4.0 2 2 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2334) CarboxypepD_reg PF13620.6 AJZ75459.1 - 1.1e-05 25.6 0.1 1.2 9.5 0.0 3.8 3 1 0 3 3 3 2 Carboxypeptidase regulatory-like domain SpaA PF17802.1 AJZ75459.1 - 3.5e-05 24.0 2.1 0.014 15.7 0.6 3.0 2 0 0 2 2 2 2 Prealbumin-like fold domain SdrD_B PF17210.3 AJZ75459.1 - 0.00061 20.0 0.9 0.26 11.5 0.2 2.9 2 0 0 2 2 2 2 SdrD B-like domain DUF4460 PF14687.6 AJZ75459.1 - 0.13 12.3 1.7 2.8 8.1 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) FAP206 PF12018.8 AJZ75460.1 - 0.0073 15.8 3.0 0.0073 15.8 3.0 2.1 1 1 1 2 2 2 2 Domain of unknown function DUF892 PF05974.12 AJZ75460.1 - 0.24 11.4 8.3 0.09 12.8 4.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF892) DUF4407 PF14362.6 AJZ75460.1 - 0.39 10.0 8.7 0.57 9.5 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GLE1 PF07817.13 AJZ75460.1 - 0.57 9.3 8.8 0.035 13.3 3.5 1.7 2 0 0 2 2 2 0 GLE1-like protein Helicase_IV_N PF12462.8 AJZ75460.1 - 1.7 8.6 13.9 1.3 9.0 3.7 2.5 1 1 1 2 2 2 0 DNA helicase IV / RNA helicase N terminal SlyX PF04102.12 AJZ75460.1 - 2.1 9.0 10.9 0.61 10.7 6.1 2.3 2 0 0 2 2 2 0 SlyX DUF1664 PF07889.12 AJZ75460.1 - 3.2 7.8 16.9 0.33 11.0 5.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HAUS6_N PF14661.6 AJZ75460.1 - 9.3 5.8 17.7 1.1 8.8 12.2 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus ParBc PF02195.18 AJZ75461.1 - 3e-19 69.1 0.1 6.1e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_7 PF02796.15 AJZ75461.1 - 0.033 14.3 0.0 0.13 12.3 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase GyrB_insert PF18053.1 AJZ75461.1 - 0.093 12.6 0.8 0.31 10.9 0.6 1.9 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain XPG_I PF00867.18 AJZ75462.1 - 1.9e-26 92.3 0.0 3.8e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 AJZ75462.1 - 3.4e-20 72.4 0.0 9e-20 71.0 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 AJZ75462.1 - 1e-05 26.1 0.0 2.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF4878 PF12870.7 AJZ75462.1 - 0.02 15.2 0.2 0.056 13.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) Bul1_C PF04426.12 AJZ75463.1 - 0.01 15.3 0.3 0.016 14.7 0.1 1.3 1 1 0 1 1 1 0 Bul1 C terminus Internalin_N PF12354.8 AJZ75463.1 - 0.019 15.0 0.8 0.058 13.5 0.8 1.9 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal Pox_I5 PF04713.12 AJZ75463.1 - 0.046 13.8 0.4 0.067 13.2 0.4 1.3 1 0 0 1 1 1 0 Poxvirus protein I5 RecR PF02132.15 AJZ75464.1 - 0.0095 15.5 0.7 0.034 13.7 1.0 1.7 2 0 0 2 2 2 1 RecR protein AMP-binding PF00501.28 AJZ75465.1 - 5.8e-95 318.4 0.0 7.1e-95 318.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AJZ75465.1 - 2.6e-23 82.8 0.0 5.2e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AJZ75465.1 - 3e-14 52.7 3.1 3e-14 52.7 3.1 2.5 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus CdvA PF18822.1 AJZ75466.1 - 4.6e-30 104.0 9.7 8.3e-30 103.1 9.7 1.4 1 0 0 1 1 1 1 CdvA-like coiled-coil domain Pox_I1 PF03289.13 AJZ75466.1 - 0.013 14.7 3.0 0.017 14.3 3.0 1.1 1 0 0 1 1 1 0 Poxvirus protein I1 PRC PF05239.16 AJZ75466.1 - 0.014 15.5 1.8 0.03 14.4 1.8 1.5 1 0 0 1 1 1 0 PRC-barrel domain MerR-DNA-bind PF09278.11 AJZ75466.1 - 0.046 14.3 2.8 4.1 8.0 0.0 2.5 2 1 0 2 2 2 0 MerR, DNA binding Thy1 PF02511.15 AJZ75467.1 - 1.2e-32 113.2 0.7 7.4e-19 68.3 0.8 2.2 2 0 0 2 2 2 2 Thymidylate synthase complementing protein DUF3510 PF12022.8 AJZ75467.1 - 0.026 14.9 1.7 0.038 14.4 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) SelR PF01641.18 AJZ75468.1 - 3.3e-54 182.1 0.5 3.8e-54 181.9 0.5 1.0 1 0 0 1 1 1 1 SelR domain HECT_2 PF09814.9 AJZ75468.1 - 0.003 16.5 1.3 0.11 11.3 0.0 2.0 1 1 0 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 AJZ75468.1 - 0.0063 16.7 0.3 0.011 15.9 0.3 1.4 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Jas PF16135.5 AJZ75468.1 - 0.073 13.3 0.9 0.74 10.0 0.1 2.1 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling Homoserine_dh PF00742.19 AJZ75469.1 - 2e-53 180.9 0.2 3.1e-53 180.2 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase ELFV_dehydrog PF00208.21 AJZ75469.1 - 4e-06 26.7 0.1 1e-05 25.4 0.1 1.7 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_3 PF03447.16 AJZ75469.1 - 1.5e-05 25.6 0.0 5.2e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Baculo_LEF-2 PF03041.14 AJZ75469.1 - 0.11 12.1 0.3 12 5.6 0.0 2.1 2 0 0 2 2 2 0 lef-2 PUA PF01472.20 AJZ75470.1 - 6.1e-19 67.8 0.2 9.5e-19 67.1 0.2 1.3 1 0 0 1 1 1 1 PUA domain RelA_SpoT PF04607.17 AJZ75472.1 - 6.8e-22 78.0 0.1 2.1e-21 76.4 0.1 1.9 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Peptidase_M20 PF01546.28 AJZ75473.1 - 1.8e-33 116.0 0.0 2.2e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AJZ75473.1 - 5.5e-16 58.5 0.0 9.1e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Tox-PL-2 PF15643.6 AJZ75473.1 - 0.064 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Papain fold toxin 2 Nuc_deoxyrib_tr PF05014.15 AJZ75473.1 - 0.084 12.9 0.0 1.4 8.9 0.0 2.7 3 0 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase Latexin PF06907.12 AJZ75473.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Latexin Carb_kinase PF01256.17 AJZ75474.1 - 1.9e-47 161.8 2.8 2.2e-47 161.6 2.8 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 AJZ75474.1 - 3.7e-09 36.3 0.2 5.9e-09 35.7 0.2 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 AJZ75474.1 - 6.4e-06 25.7 0.1 1e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Interferon PF00143.19 AJZ75475.1 - 0.0013 18.9 7.2 0.0013 18.9 7.2 1.7 1 1 0 2 2 2 1 Interferon alpha/beta domain Spidroin_N PF16763.5 AJZ75475.1 - 0.046 13.7 0.3 0.046 13.7 0.3 1.6 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF2175 PF09943.9 AJZ75475.1 - 0.44 10.9 16.6 0.72 10.2 4.7 3.2 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) OmpH PF03938.14 AJZ75475.1 - 9 6.6 20.8 2.4 8.5 17.5 1.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) GCD14 PF08704.10 AJZ75476.1 - 6e-32 111.3 0.0 9.7e-32 110.6 0.0 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 AJZ75476.1 - 4.5e-08 33.1 0.0 6.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 AJZ75476.1 - 1.3e-07 31.5 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJZ75476.1 - 3.4e-07 30.9 0.0 9.9e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 AJZ75476.1 - 6.5e-07 30.3 0.0 1.4e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AJZ75476.1 - 1.8e-06 27.5 0.0 3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 AJZ75476.1 - 6e-05 23.6 0.0 0.00017 22.2 0.0 1.8 2 1 0 2 2 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AJZ75476.1 - 0.00035 20.3 0.0 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_3 PF01596.17 AJZ75476.1 - 0.00073 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.20 AJZ75476.1 - 0.0008 18.6 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.13 AJZ75476.1 - 0.00096 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 AJZ75476.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 AJZ75476.1 - 0.0064 16.3 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_16 PF10294.9 AJZ75476.1 - 0.0078 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 AJZ75476.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Fibrillarin PF01269.17 AJZ75476.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltransf_12 PF08242.12 AJZ75476.1 - 0.018 15.8 0.0 0.054 14.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 AJZ75476.1 - 0.044 13.8 0.0 0.08 12.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 AJZ75476.1 - 0.083 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.19 AJZ75476.1 - 0.094 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF1726 PF08351.11 AJZ75476.1 - 0.1 12.6 0.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) PDZ_6 PF17820.1 AJZ75476.1 - 0.15 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 PDZ domain Response_reg PF00072.24 AJZ75477.1 - 4.6e-17 62.2 0.5 6.8e-17 61.6 0.2 1.4 2 0 0 2 2 2 1 Response regulator receiver domain DUF1487 PF07368.11 AJZ75477.1 - 0.0047 16.4 0.4 0.0091 15.5 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Ead_Ea22 PF13935.6 AJZ75477.1 - 0.02 15.6 0.5 0.023 15.3 0.5 1.4 1 1 0 1 1 1 0 Ead/Ea22-like protein TPR_18 PF13512.6 AJZ75477.1 - 0.087 12.9 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DALR_1 PF05746.15 AJZ75478.1 - 7e-27 94.0 0.1 7e-27 94.0 0.1 2.2 3 0 0 3 3 3 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 AJZ75478.1 - 2.8e-24 85.7 2.3 4.2e-18 65.4 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 AJZ75478.1 - 2.9e-13 50.2 0.0 1.2e-12 48.2 0.0 2.1 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 AJZ75478.1 - 0.00046 19.6 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 AJZ75478.1 - 0.016 13.9 0.8 0.03 13.1 0.1 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (M) MMR_HSR1_Xtn PF16897.5 AJZ75479.1 - 1.5e-29 102.1 1.4 3.5e-29 100.9 1.4 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 AJZ75479.1 - 1.6e-23 83.0 0.0 3.5e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 AJZ75479.1 - 3.2e-22 78.3 0.0 5.7e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 AJZ75479.1 - 6.4e-15 55.0 0.6 1.4e-13 50.6 0.0 2.3 1 1 1 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AJZ75479.1 - 1.4e-05 25.1 1.9 0.0037 17.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 AJZ75479.1 - 0.00015 21.9 2.2 0.066 13.3 0.4 2.8 2 1 1 3 3 3 2 Dynamin family Arf PF00025.21 AJZ75479.1 - 0.00026 20.5 0.6 0.018 14.5 0.1 2.6 1 1 1 2 2 2 1 ADP-ribosylation factor family AIG1 PF04548.16 AJZ75479.1 - 0.00052 19.4 0.1 0.0012 18.2 0.0 1.6 2 0 0 2 2 2 1 AIG1 family SRPRB PF09439.10 AJZ75479.1 - 0.011 15.1 0.6 0.025 14.0 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 AJZ75479.1 - 0.032 14.6 0.2 0.56 10.6 0.3 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 AJZ75479.1 - 0.043 14.1 0.2 0.087 13.1 0.2 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 AJZ75479.1 - 0.11 12.1 1.4 7.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Ras family AAA_33 PF13671.6 AJZ75479.1 - 0.12 12.5 0.2 0.33 11.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain Collagen PF01391.18 AJZ75482.1 - 1.5e-60 200.8 230.8 7.7e-10 38.4 32.4 7.2 1 1 4 5 5 5 4 Collagen triple helix repeat (20 copies) TPR_2 PF07719.17 AJZ75483.1 - 1.3e-20 71.8 0.0 2.6e-05 24.0 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 AJZ75483.1 - 1.3e-17 62.8 0.2 0.0024 17.6 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 AJZ75483.1 - 7.1e-15 55.4 0.0 1.4e-06 28.9 0.0 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 AJZ75483.1 - 5.3e-11 41.8 2.3 0.0032 17.6 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 AJZ75483.1 - 1.1e-10 41.9 0.1 1.7e-06 28.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 AJZ75483.1 - 1.1e-10 41.1 0.6 0.0029 17.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 AJZ75483.1 - 1.2e-10 41.2 0.0 0.0036 18.0 0.1 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 AJZ75483.1 - 1.1e-08 34.6 4.5 0.0076 15.9 0.0 4.5 2 1 2 4 4 4 2 TPR repeat ANAPC3 PF12895.7 AJZ75483.1 - 4.2e-08 33.3 4.9 3e-05 24.2 0.3 1.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 AJZ75483.1 - 1.1e-07 31.8 0.5 0.019 15.0 0.0 4.0 2 1 2 4 4 3 3 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 AJZ75483.1 - 5e-07 29.9 0.4 0.00014 22.1 0.4 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 AJZ75483.1 - 5.4e-07 29.7 0.1 0.0012 18.9 0.0 2.7 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 AJZ75483.1 - 1.2e-06 28.7 0.9 0.0038 17.8 0.2 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat DUF2666 PF10869.8 AJZ75483.1 - 0.0002 21.6 2.7 0.0002 21.6 2.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2666) YjcQ PF09639.10 AJZ75483.1 - 0.0024 18.0 0.3 0.011 15.9 0.3 2.1 1 0 0 1 1 1 1 YjcQ protein TrmB PF01978.19 AJZ75483.1 - 0.0048 16.8 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB YfiO PF13525.6 AJZ75483.1 - 0.0067 16.2 0.4 0.2 11.4 0.0 2.3 1 1 0 2 2 2 1 Outer membrane lipoprotein SRP_TPR_like PF17004.5 AJZ75483.1 - 0.011 15.8 2.3 0.016 15.2 0.6 2.0 2 0 0 2 2 2 0 Putative TPR-like repeat HTH_27 PF13463.6 AJZ75483.1 - 0.021 15.3 0.0 0.068 13.7 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain TPR_18 PF13512.6 AJZ75483.1 - 0.024 14.8 1.1 6.9 6.8 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF4423 PF14394.6 AJZ75483.1 - 0.086 12.5 5.1 0.097 12.4 1.3 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4423) TPR_10 PF13374.6 AJZ75483.1 - 0.18 11.7 0.0 25 4.9 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 AJZ75483.1 - 0.2 11.8 0.7 35 4.7 0.5 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Rhodanese PF00581.20 AJZ75484.1 - 2.9e-36 124.2 0.1 4.2e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Bac_GH3_C PF18034.1 AJZ75484.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain NIR_SIR PF01077.22 AJZ75485.1 - 2.8e-39 134.2 0.0 2e-30 105.4 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AJZ75485.1 - 9.3e-36 121.5 0.0 5.1e-17 61.5 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Thi4 PF01946.17 AJZ75486.1 - 8e-65 218.4 0.0 9.5e-65 218.1 0.0 1.0 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 AJZ75486.1 - 2.2e-11 43.5 0.1 3.2e-06 26.5 0.1 2.2 1 1 1 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 AJZ75486.1 - 1.5e-08 34.5 0.0 2.6e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AJZ75486.1 - 9.7e-08 32.1 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AJZ75486.1 - 3.8e-07 29.7 0.1 6.1e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AJZ75486.1 - 6.7e-07 28.8 0.1 9.2e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AJZ75486.1 - 6.5e-06 25.1 0.1 9.6e-06 24.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 AJZ75486.1 - 1.7e-05 24.2 0.5 2.6e-05 23.6 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AJZ75486.1 - 2e-05 24.4 0.8 0.00018 21.2 0.5 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AJZ75486.1 - 5e-05 22.5 0.1 0.0048 16.0 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 AJZ75486.1 - 0.001 18.2 0.2 0.0019 17.4 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 AJZ75486.1 - 0.04 12.8 0.1 6.9 5.4 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 AJZ75486.1 - 0.041 14.4 0.0 0.097 13.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 AJZ75486.1 - 0.049 13.9 0.1 0.17 12.2 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 AJZ75486.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 AJZ75488.1 - 2.8e-55 187.6 0.5 3.3e-55 187.4 0.5 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AJZ75488.1 - 9.2e-28 97.4 3.6 8.4e-24 84.4 0.3 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJZ75488.1 - 5.2e-18 65.4 3.4 1.5e-17 63.9 0.2 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AJZ75488.1 - 5.7e-08 32.3 3.3 0.00035 19.8 0.1 4.3 3 1 1 5 5 5 2 FAD binding domain GIDA PF01134.22 AJZ75488.1 - 1.1e-07 31.3 0.4 0.02 14.0 0.0 4.0 4 0 0 4 4 4 2 Glucose inhibited division protein A HI0933_like PF03486.14 AJZ75488.1 - 7.6e-06 24.9 0.6 0.022 13.5 0.1 3.4 4 1 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 AJZ75488.1 - 4.5e-05 22.8 0.1 0.0038 16.4 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 AJZ75488.1 - 8.8e-05 21.8 0.0 0.005 16.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 AJZ75488.1 - 0.00048 20.5 0.2 0.003 18.0 0.1 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 AJZ75488.1 - 0.0014 18.3 5.2 0.15 11.6 0.0 3.1 2 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AJZ75488.1 - 0.002 17.4 0.5 0.17 11.1 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 AJZ75488.1 - 0.0023 17.3 0.1 0.01 15.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AJZ75488.1 - 0.0027 17.7 1.0 0.58 10.1 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 AJZ75488.1 - 0.015 15.5 0.1 0.073 13.3 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 AJZ75488.1 - 0.023 13.5 0.3 0.82 8.4 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 AJZ75488.1 - 0.13 11.3 0.3 4.9 6.1 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Response_reg PF00072.24 AJZ75489.1 - 7.7e-16 58.3 0.0 1.4e-15 57.5 0.0 1.4 1 1 0 1 1 1 1 Response regulator receiver domain PALP PF00291.25 AJZ75490.1 - 6.8e-64 216.1 0.0 8.9e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TusA PF01206.17 AJZ75491.1 - 2.1e-24 85.1 0.0 2.3e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 AJZ75491.1 - 0.024 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) IQ PF00612.27 AJZ75492.1 - 0.032 14.0 0.1 0.064 13.1 0.1 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF1454 PF07305.12 AJZ75492.1 - 0.063 12.7 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) NusG_add PF18298.1 AJZ75492.1 - 0.12 12.6 0.0 1 9.6 0.0 2.0 2 0 0 2 2 2 0 NusG additional domain F420_ligase PF01996.16 AJZ75493.1 - 5.9e-49 166.6 0.4 7.2e-49 166.3 0.4 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase HAD PF12710.7 AJZ75494.1 - 4.6e-11 43.5 0.0 5.5e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AJZ75494.1 - 1.6e-07 31.8 0.1 1.8e-06 28.4 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AJZ75494.1 - 0.0002 21.2 0.2 0.0026 17.6 0.2 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase tRNA-synt_2b PF00587.25 AJZ75495.1 - 1.4e-20 74.1 0.0 2.5e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 AJZ75495.1 - 1.3e-19 70.1 1.0 4.2e-19 68.5 1.0 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 AJZ75495.1 - 1.8e-17 63.3 0.2 3.9e-17 62.2 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain ABC_tran PF00005.27 AJZ75496.1 - 1.2e-31 110.1 0.1 1.7e-31 109.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AJZ75496.1 - 1.6e-05 25.3 0.1 3.8e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.6 AJZ75496.1 - 0.00014 22.1 0.4 0.0023 18.2 0.4 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AJZ75496.1 - 0.00048 19.6 0.1 0.00077 19.0 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AJZ75496.1 - 0.00054 20.4 0.0 0.00072 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AJZ75496.1 - 0.0018 18.0 0.1 0.0035 17.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 AJZ75496.1 - 0.0039 16.3 0.2 0.0088 15.1 0.1 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 AJZ75496.1 - 0.0051 17.2 0.5 0.048 14.1 0.5 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AJZ75496.1 - 0.006 16.5 0.1 0.0097 15.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 AJZ75496.1 - 0.0083 16.0 2.2 0.79 9.5 0.4 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DnaB_C PF03796.15 AJZ75496.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 AJZ75496.1 - 0.025 14.3 0.1 0.053 13.2 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 AJZ75496.1 - 0.03 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 AJZ75496.1 - 0.033 13.7 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_13 PF13166.6 AJZ75496.1 - 0.038 12.7 0.0 0.11 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AJZ75496.1 - 0.053 12.7 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.25 AJZ75496.1 - 0.054 13.1 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 AJZ75496.1 - 0.063 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_10 PF12846.7 AJZ75496.1 - 0.088 11.7 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.22 AJZ75496.1 - 0.11 12.9 0.5 1.2 9.5 0.2 2.6 2 1 1 3 3 3 0 RNA helicase Mg_chelatase PF01078.21 AJZ75496.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AJZ75496.1 - 0.11 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Myosin_head PF00063.21 AJZ75496.1 - 0.12 10.5 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) IstB_IS21 PF01695.17 AJZ75496.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 AJZ75496.1 - 0.17 11.8 0.1 0.65 9.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 AJZ75496.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-Di19 PF05605.12 AJZ75497.1 - 0.025 14.9 0.1 0.037 14.3 0.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 AJZ75497.1 - 0.073 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 BED zinc finger DUF5402 PF17393.2 AJZ75497.1 - 0.087 12.8 0.0 0.093 12.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5402) PAC2 PF09754.9 AJZ75498.1 - 1.3e-21 77.6 0.0 1.5e-21 77.4 0.0 1.0 1 0 0 1 1 1 1 PAC2 family Tfb2_C PF18307.1 AJZ75498.1 - 0.022 15.2 0.0 11 6.6 0.0 2.6 2 1 0 2 2 2 0 Transcription factor Tfb2 (p52) C-terminal domain LysE PF01810.18 AJZ75499.1 - 9.7e-28 96.9 16.5 1.2e-27 96.6 16.5 1.1 1 0 0 1 1 1 1 LysE type translocator DUF4342 PF14242.6 AJZ75499.1 - 0.2 11.7 1.9 0.25 11.4 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4342) MCM_OB PF17207.3 AJZ75500.1 - 0.066 13.1 0.4 0.076 12.9 0.4 1.0 1 0 0 1 1 1 0 MCM OB domain Fer2_BFD PF04324.15 AJZ75500.1 - 0.084 13.2 0.2 0.13 12.7 0.2 1.4 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain IMS PF00817.20 AJZ75501.1 - 2.8e-40 137.8 0.1 8.1e-40 136.3 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 AJZ75501.1 - 2.7e-11 44.2 0.5 5.2e-11 43.3 0.5 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AJZ75501.1 - 1.2e-07 31.7 0.0 2.8e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DNA_pol_lambd_f PF10391.9 AJZ75501.1 - 0.014 15.2 0.0 0.045 13.6 0.0 1.8 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 AJZ75501.1 - 0.028 14.7 0.1 0.58 10.4 0.0 2.5 2 0 0 2 2 2 0 Pathogenicity locus HHH_5 PF14520.6 AJZ75501.1 - 0.13 12.8 0.0 0.55 10.9 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF998 PF06197.13 AJZ75502.1 - 0.00086 19.0 1.3 0.00086 19.0 1.3 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF998) Got1 PF04178.12 AJZ75502.1 - 0.018 15.5 3.4 0.018 15.5 3.4 3.1 3 1 1 4 4 4 0 Got1/Sft2-like family Tubulin PF00091.25 AJZ75504.1 - 9.9e-16 58.5 0.0 2e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Nre_N PF04894.12 AJZ75505.1 - 2.4e-86 289.9 0.0 3.3e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Archaeal Nre, N-terminal Nre_C PF04895.12 AJZ75505.1 - 9.3e-36 122.1 0.0 1.6e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Archaeal Nre, C-terminal Wzy_C PF04932.15 AJZ75507.1 - 1.7 8.2 6.4 2.5 7.7 6.4 1.5 1 1 0 1 1 1 0 O-Antigen ligase zf-C2H2 PF00096.26 AJZ75509.1 - 0.00038 20.8 1.3 0.0007 19.9 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 AJZ75509.1 - 0.0007 19.3 1.2 0.0017 18.1 1.2 1.7 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 AJZ75509.1 - 0.0016 19.1 1.5 0.0037 18.0 1.5 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger BAR PF03114.18 AJZ75509.1 - 0.017 14.8 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 BAR domain RNA_POL_M_15KD PF02150.16 AJZ75509.1 - 0.066 13.1 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-Mss51 PF13824.6 AJZ75509.1 - 0.066 13.3 0.8 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 FAT PF02259.23 AJZ75509.1 - 0.082 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 FAT domain UPF0547 PF10571.9 AJZ75509.1 - 0.14 12.2 0.4 0.27 11.4 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 ABC2_membrane_3 PF12698.7 AJZ75510.1 - 0.017 14.3 3.5 0.02 14.0 3.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein GIDA_assoc PF13932.6 AJZ75510.1 - 0.62 10.2 7.7 0.94 9.6 7.7 1.4 1 1 0 1 1 1 0 GidA associated domain Med9 PF07544.13 AJZ75510.1 - 0.69 10.0 7.6 0.072 13.2 2.1 2.2 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF3887 PF13026.6 AJZ75510.1 - 1.2 10.0 6.3 20 6.1 6.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3887) SURF1 PF02104.15 AJZ75511.1 - 0.062 13.5 0.0 0.073 13.3 0.0 1.2 1 0 0 1 1 1 0 SURF1 family TRAP_alpha PF03896.16 AJZ75511.1 - 4.4 6.4 11.4 0.26 10.5 2.9 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit NAD_binding_2 PF03446.15 AJZ75512.1 - 2e-40 138.6 0.3 3.6e-40 137.7 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AJZ75512.1 - 1.5e-21 76.8 0.2 2.2e-21 76.3 0.2 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AJZ75512.1 - 6e-08 33.2 0.1 1.5e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AJZ75512.1 - 1.1e-06 28.1 0.0 3e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 AJZ75512.1 - 8.3e-06 25.5 0.1 1.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 AJZ75512.1 - 0.0037 17.2 0.1 0.0075 16.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Rossmann-like PF10727.9 AJZ75512.1 - 0.011 15.5 0.1 0.056 13.3 0.1 1.9 1 1 1 2 2 2 0 Rossmann-like domain IlvN PF07991.12 AJZ75512.1 - 0.013 15.1 0.1 0.045 13.3 0.1 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 AJZ75512.1 - 0.014 15.3 0.1 0.033 14.1 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AJZ75512.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 AJZ75512.1 - 0.077 12.5 0.2 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 NmrA-like family zf-RRN7 PF11781.8 AJZ75513.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TPR_1 PF00515.28 AJZ75514.1 - 1.2e-19 69.3 0.3 6.6e-07 28.9 0.1 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 AJZ75514.1 - 3.3e-14 51.8 0.0 0.0016 18.4 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 AJZ75514.1 - 4.8e-10 39.0 0.6 0.00051 19.7 0.0 4.2 2 1 2 4 4 4 2 TPR repeat TPR_8 PF13181.6 AJZ75514.1 - 1.5e-09 37.3 0.4 0.12 12.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AJZ75514.1 - 4.8e-09 36.7 0.0 0.00011 22.8 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 AJZ75514.1 - 1.2e-08 35.1 0.4 0.26 11.6 0.1 3.5 2 2 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 AJZ75514.1 - 2.1e-08 33.6 0.0 0.56 10.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 AJZ75514.1 - 6.6e-08 32.8 0.0 1 10.3 0.0 4.1 1 1 3 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJZ75514.1 - 1.2e-07 31.7 0.0 0.06 13.4 0.0 3.4 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 AJZ75514.1 - 1.9e-07 31.1 0.0 0.00065 19.8 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AJZ75514.1 - 6.5e-07 29.5 0.3 0.009 16.2 0.1 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AJZ75514.1 - 3.9e-06 27.1 0.0 0.95 10.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 AJZ75514.1 - 4.8e-05 23.4 0.2 0.3 11.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 AJZ75514.1 - 4.9e-05 23.7 0.1 0.12 12.9 0.0 2.9 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 AJZ75514.1 - 0.0019 18.0 0.1 1.3 9.0 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 AJZ75514.1 - 0.0021 18.0 2.1 1.1 9.3 0.0 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat NARP1 PF12569.8 AJZ75514.1 - 0.02 13.8 0.1 0.3 10.0 0.0 1.9 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 SRP_TPR_like PF17004.5 AJZ75514.1 - 0.065 13.2 0.3 15 5.7 0.2 2.7 1 1 1 2 2 2 0 Putative TPR-like repeat DUF3856 PF12968.7 AJZ75514.1 - 0.11 12.5 0.0 3.4 7.7 0.0 2.9 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) DZR PF12773.7 AJZ75515.1 - 0.62 10.1 11.9 4.1 7.5 11.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon PolC_DP2 PF03833.13 AJZ75515.1 - 1.6 6.5 4.8 1.5 6.6 4.8 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 SBP_bac_5 PF00496.22 AJZ75516.1 - 3e-25 89.0 12.0 1.7e-20 73.3 0.0 3.9 2 2 1 3 3 3 3 Bacterial extracellular solute-binding proteins, family 5 Middle Mrr_cat PF04471.12 AJZ75517.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Hjc PF01870.18 AJZ75517.1 - 0.006 16.5 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) NERD PF08378.11 AJZ75517.1 - 0.097 13.1 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Nuclease-related domain DUF2070 PF09843.9 AJZ75518.1 - 4.7e-117 391.6 0.6 5.8e-117 391.3 0.6 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) NPV_P10 PF05531.12 AJZ75519.1 - 0.068 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 AJZ75519.1 - 0.071 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3937 PF13073.6 AJZ75519.1 - 0.08 13.1 1.2 0.58 10.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) Auto_anti-p27 PF06677.12 AJZ75520.1 - 2.4e-12 46.8 2.5 3.4e-12 46.3 2.5 1.2 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TIP120 PF08623.10 AJZ75520.1 - 0.004 17.0 1.5 0.0058 16.4 1.5 1.3 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) TF_Zn_Ribbon PF08271.12 AJZ75520.1 - 0.01 15.3 1.4 0.016 14.7 1.4 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding DUF3422 PF11902.8 AJZ75520.1 - 0.024 13.7 2.2 0.029 13.5 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) COG2 PF06148.11 AJZ75520.1 - 0.041 14.0 0.7 0.051 13.7 0.7 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-C4pol PF14260.6 AJZ75520.1 - 0.043 14.3 0.5 0.11 12.9 0.5 1.8 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta NPV_P10 PF05531.12 AJZ75520.1 - 0.19 12.2 4.2 0.41 11.1 4.2 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein zf-ribbon_3 PF13248.6 AJZ75520.1 - 2.1 7.9 5.6 10 5.7 5.3 2.1 1 1 1 2 2 2 0 zinc-ribbon domain SUI1 PF01253.22 AJZ75521.1 - 5.8e-16 58.8 0.0 7.8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DTW PF03942.15 AJZ75521.1 - 0.07 12.8 0.1 0.076 12.7 0.1 1.2 1 0 0 1 1 1 0 DTW domain CPBP PF02517.16 AJZ75522.1 - 2.9e-11 43.6 14.9 1.7e-10 41.1 14.9 2.4 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease Pox_I5 PF04713.12 AJZ75522.1 - 0.038 14.0 0.7 0.038 14.0 0.7 2.5 3 0 0 3 3 3 0 Poxvirus protein I5 UPF0052 PF01933.18 AJZ75523.1 - 4.9e-55 186.8 0.0 5.8e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 CofC PF01983.16 AJZ75524.1 - 3.9e-26 91.6 0.8 4.5e-26 91.4 0.8 1.0 1 0 0 1 1 1 1 Guanylyl transferase CofC like NTP_transf_3 PF12804.7 AJZ75524.1 - 1.3e-06 28.9 0.0 1.6e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 AJZ75524.1 - 0.00028 20.6 0.2 0.00044 19.9 0.2 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase CTP_transf_3 PF02348.19 AJZ75524.1 - 0.0094 15.9 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Toprim_3 PF13362.6 AJZ75524.1 - 0.041 14.2 0.0 0.069 13.5 0.0 1.3 1 0 0 1 1 1 0 Toprim domain MG2 PF01835.19 AJZ75525.1 - 8.3e-25 87.1 10.3 9.8e-07 29.1 0.0 9.7 8 3 1 9 9 9 4 MG2 domain LTD PF00932.19 AJZ75525.1 - 2.2e-15 57.0 0.9 1.7e-14 54.1 0.9 2.6 1 0 0 1 1 1 1 Lamin Tail Domain Arrestin_C PF02752.22 AJZ75525.1 - 1.9e-05 25.1 9.9 0.42 11.1 0.7 6.5 6 2 1 7 7 7 2 Arrestin (or S-antigen), C-terminal domain A2M_BRD PF07703.14 AJZ75525.1 - 0.0029 18.0 6.5 1.4 9.3 0.2 4.9 3 2 1 4 4 4 2 Alpha-2-macroglobulin bait region domain DUF3324 PF11797.8 AJZ75525.1 - 0.031 14.3 4.1 11 6.0 0.1 4.3 4 1 1 5 5 5 0 Protein of unknown function C-terminal (DUF3324) DUF4198 PF10670.9 AJZ75525.1 - 3.6 7.9 7.4 26 5.1 0.0 4.4 4 1 0 5 5 5 0 Domain of unknown function (DUF4198) Peptidase_M24 PF00557.24 AJZ75526.1 - 1.8e-30 106.2 0.0 2e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 ParD PF09386.10 AJZ75526.1 - 0.08 13.3 0.4 37 4.8 0.0 3.3 2 1 1 3 3 3 0 Antitoxin ParD COMP PF11598.8 AJZ75527.1 - 0.36 11.3 0.2 0.36 11.3 0.2 1.8 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Zn-ribbon_8 PF09723.10 AJZ75527.1 - 2.3 8.4 7.1 1.7 8.9 0.5 1.9 1 1 1 2 2 2 0 Zinc ribbon domain DUF1512 PF07431.12 AJZ75528.1 - 9.9e-129 429.4 5.1 1.1e-128 429.2 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1512) DUF948 PF06103.11 AJZ75528.1 - 0.04 14.2 0.1 0.31 11.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2795 PF11387.8 AJZ75528.1 - 0.16 12.2 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) TBP PF00352.21 AJZ75529.1 - 6.1e-55 183.1 0.0 7.5e-28 96.3 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 AJZ75529.1 - 1.8e-07 31.2 0.0 0.0013 18.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) B3_4 PF03483.17 AJZ75529.1 - 0.09 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 B3/4 domain tRNA_bind PF01588.20 AJZ75530.1 - 5e-19 68.2 0.0 5.7e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Putative tRNA binding domain PRIMA1 PF16101.5 AJZ75531.1 - 0.0047 17.0 2.7 0.0076 16.3 2.7 1.3 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Polyketide_cyc2 PF10604.9 AJZ75532.1 - 6.9e-15 55.6 0.0 7.7e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AJZ75532.1 - 2.6e-09 37.4 0.0 3.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 AJZ75532.1 - 0.0005 20.3 0.1 0.00067 19.9 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Glycos_transf_2 PF00535.26 AJZ75533.1 - 9.8e-25 87.3 0.0 1.4e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AJZ75533.1 - 3.6e-17 63.0 0.0 5.3e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AJZ75533.1 - 5.4e-10 39.0 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 AJZ75533.1 - 0.0012 19.3 0.0 0.0039 17.7 0.0 1.9 1 1 1 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AJZ75533.1 - 0.0053 16.3 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Trypsin_2 PF13365.6 AJZ75534.1 - 2e-35 122.9 0.6 5.9e-35 121.4 0.2 2.0 3 0 0 3 3 3 1 Trypsin-like peptidase domain Trypsin PF00089.26 AJZ75534.1 - 5.1e-14 52.6 0.3 4.7e-13 49.5 0.0 2.4 2 1 0 2 2 2 1 Trypsin PDZ_2 PF13180.6 AJZ75534.1 - 1.1e-11 44.8 2.0 1.1e-10 41.6 0.9 2.7 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 AJZ75534.1 - 0.0001 22.1 2.0 0.24 11.3 0.0 3.3 3 0 0 3 3 3 2 PDZ domain Peptidase_S29 PF02907.15 AJZ75534.1 - 0.0016 18.2 0.0 0.0042 16.8 0.0 1.7 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 AJZ75534.1 - 0.0043 15.8 0.1 0.02 13.5 0.1 1.8 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S7 PF00949.21 AJZ75534.1 - 0.088 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease PDZ PF00595.24 AJZ75534.1 - 0.33 11.3 3.3 3.6 8.0 0.3 3.7 3 1 0 3 3 3 0 PDZ domain Radical_SAM PF04055.21 AJZ75535.1 - 1.2e-07 32.3 0.0 1.8e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily BATS PF06968.13 AJZ75535.1 - 0.16 12.1 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain PmbA_TldD PF01523.16 AJZ75536.1 - 1.3e-40 140.1 0.5 1.7e-40 139.7 0.5 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase DUF3658 PF12395.8 AJZ75536.1 - 0.055 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function PAC2 PF09754.9 AJZ75538.1 - 4.1e-39 134.8 0.0 4.7e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 PAC2 family DUF3410 PF11890.8 AJZ75538.1 - 0.049 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) IL4 PF00727.18 AJZ75538.1 - 0.053 13.8 0.0 0.087 13.1 0.0 1.4 1 0 0 1 1 1 0 Interleukin 4 Atg8 PF02991.16 AJZ75538.1 - 0.056 13.6 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Autophagy protein Atg8 ubiquitin like AIRS_C PF02769.22 AJZ75539.1 - 1.8e-23 83.4 0.0 2.8e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AJZ75539.1 - 2.2e-15 57.1 1.5 4.4e-15 56.1 1.5 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Na_H_Exchanger PF00999.21 AJZ75540.1 - 2.6e-59 200.9 54.6 3.4e-59 200.6 54.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PspB PF06667.12 AJZ75540.1 - 0.13 12.3 0.7 0.68 10.0 0.1 2.5 2 0 0 2 2 2 0 Phage shock protein B DUF2175 PF09943.9 AJZ75541.1 - 8.8e-05 22.7 1.6 8.8e-05 22.7 1.6 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) LIM PF00412.22 AJZ75541.1 - 0.0013 18.9 0.3 0.0023 18.1 0.3 1.4 1 0 0 1 1 1 1 LIM domain PIN_6 PF17146.4 AJZ75541.1 - 0.0021 18.5 0.3 0.0032 18.0 0.3 1.3 1 0 0 1 1 1 1 PIN domain of ribonuclease Radical_SAM_C PF16199.5 AJZ75542.1 - 2.8e-23 81.7 0.5 5.8e-23 80.7 0.5 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 AJZ75542.1 - 2.4e-21 76.8 0.1 7.8e-21 75.2 0.0 1.9 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 AJZ75542.1 - 9.9e-06 25.8 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AJZ75542.1 - 1e-05 25.5 0.0 8.3e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain tRNA-synt_1f PF01921.18 AJZ75543.1 - 3.2e-109 365.2 0.0 4.2e-109 364.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1g PF09334.11 AJZ75543.1 - 0.017 13.9 0.5 0.19 10.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (M) P2 PF07194.11 AJZ75543.1 - 0.03 14.4 0.3 0.49 10.5 0.3 2.9 2 1 0 2 2 2 0 P2 response regulator binding domain Glyco_transf_88 PF16849.5 AJZ75543.1 - 0.059 12.3 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 88 CLASP_N PF12348.8 AJZ75543.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CLASP N terminal SdpI PF13630.6 AJZ75544.1 - 0.044 13.9 0.3 0.053 13.7 0.3 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF2207 PF09972.9 AJZ75544.1 - 0.13 11.0 0.4 0.14 10.9 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 AJZ75544.1 - 0.17 11.5 0.8 0.17 11.5 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) WEMBL PF05701.11 AJZ75545.1 - 0.0002 20.2 50.2 0.00033 19.5 15.5 3.5 1 1 2 3 3 3 2 Weak chloroplast movement under blue light DUF3584 PF12128.8 AJZ75545.1 - 0.0094 13.5 44.1 0.033 11.7 9.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) DUF745 PF05335.13 AJZ75545.1 - 0.012 15.4 42.1 0.016 15.0 14.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) TPR_MLP1_2 PF07926.12 AJZ75545.1 - 0.014 15.4 23.0 0.014 15.4 23.0 3.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 AJZ75545.1 - 0.031 14.7 45.3 0.44 11.0 16.8 2.4 1 1 1 2 2 2 0 Fez1 Golgin_A5 PF09787.9 AJZ75545.1 - 0.41 10.1 52.9 0.61 9.5 21.4 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 Filament PF00038.21 AJZ75545.1 - 0.54 9.8 47.4 0.44 10.1 11.3 2.4 1 1 1 2 2 2 0 Intermediate filament protein AAA_31 PF13614.6 AJZ75545.1 - 0.96 9.3 18.3 1.1 9.2 1.8 3.5 2 1 1 3 3 3 0 AAA domain DUF4407 PF14362.6 AJZ75545.1 - 0.98 8.7 33.0 0.59 9.4 20.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 AJZ75545.1 - 1.2 9.4 47.4 0.068 13.4 6.3 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) ERM PF00769.19 AJZ75545.1 - 2.5 7.8 54.3 23 4.7 24.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 AJZ75545.1 - 3.4 8.3 54.9 2.7 8.7 12.4 4.2 1 1 4 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GAS PF13851.6 AJZ75545.1 - 4.6 6.5 56.6 1.2 8.5 24.4 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FliJ PF02050.16 AJZ75545.1 - 5 7.4 39.4 0.21 11.8 12.1 3.5 1 1 2 3 3 3 0 Flagellar FliJ protein Spc7 PF08317.11 AJZ75545.1 - 6.5 5.5 56.8 2.4 7.0 22.7 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein CEP63 PF17045.5 AJZ75545.1 - 7 6.5 48.4 7.8 6.3 36.5 2.8 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Atg14 PF10186.9 AJZ75545.1 - 7.7 5.5 43.9 12 4.9 9.9 3.5 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-AN1 PF01428.16 AJZ75546.1 - 5.7e-07 29.6 6.1 5.7e-07 29.6 6.1 2.3 3 0 0 3 3 3 1 AN1-like Zinc finger SHOCT PF09851.9 AJZ75546.1 - 0.0046 16.7 0.9 0.0083 15.8 0.9 1.5 1 0 0 1 1 1 1 Short C-terminal domain DNA_RNApol_7kD PF03604.13 AJZ75546.1 - 0.029 14.0 0.9 3.1 7.6 0.2 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C3HC4_2 PF13923.6 AJZ75546.1 - 3 7.8 7.7 2.6 8.0 4.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DM13 PF10517.9 AJZ75547.1 - 3.5e-20 72.5 0.0 6.1e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Electron transfer DM13 DM13 PF10517.9 AJZ75548.1 - 9.6e-07 29.3 0.0 1.9e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Electron transfer DM13 DUF2407_C PF13373.6 AJZ75549.1 - 0.15 12.2 4.8 5.6 7.1 0.1 2.6 2 1 0 2 2 2 0 DUF2407 C-terminal domain DUF1691 PF07950.11 AJZ75550.1 - 0.016 15.9 0.0 0.037 14.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) DnaJ PF00226.31 AJZ75551.1 - 2e-09 37.5 0.1 4.4e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Toxin_R_bind_N PF07953.12 AJZ75551.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding Radical_SAM PF04055.21 AJZ75552.1 - 2.9e-11 44.0 0.1 5.4e-11 43.2 0.1 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AJZ75552.1 - 6.8e-08 32.9 0.3 1.5e-07 31.8 0.3 1.5 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AJZ75552.1 - 3.9e-06 27.0 0.6 1.1e-05 25.6 0.2 2.0 2 1 1 3 3 3 1 4Fe-4S single cluster domain SSURE PF11966.8 AJZ75552.1 - 0.062 13.1 0.4 0.45 10.3 0.4 2.1 1 1 0 1 1 1 0 Fibronectin-binding repeat TRAM PF01938.20 AJZ75553.1 - 2.9e-15 56.0 0.9 3.6e-15 55.7 0.9 1.1 1 0 0 1 1 1 1 TRAM domain S1 PF00575.23 AJZ75553.1 - 0.47 10.8 2.7 17 5.8 0.1 2.4 1 1 0 2 2 2 0 S1 RNA binding domain KAP_NTPase PF07693.14 AJZ75555.1 - 2e-37 129.1 6.7 3.6e-37 128.3 6.7 1.3 1 0 0 1 1 1 1 KAP family P-loop domain NB-ARC PF00931.22 AJZ75555.1 - 1.1e-06 28.1 0.2 2e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 AJZ75555.1 - 1.9e-05 24.6 0.0 0.006 16.5 0.0 3.7 2 1 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 AJZ75555.1 - 2.2e-05 24.1 0.2 0.05 13.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 AJZ75555.1 - 7.1e-05 23.3 2.7 0.0029 18.1 0.8 3.1 2 2 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AJZ75555.1 - 0.00014 22.3 0.0 0.00034 21.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 AJZ75555.1 - 0.00017 21.6 10.9 0.00024 21.1 6.5 2.8 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AJZ75555.1 - 0.00077 19.8 0.3 0.02 15.2 0.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AJZ75555.1 - 0.0027 18.2 0.3 0.023 15.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 AJZ75555.1 - 0.01 16.2 0.2 0.19 12.1 0.0 3.0 2 1 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 AJZ75555.1 - 0.013 16.0 0.2 0.036 14.6 0.2 1.8 1 1 0 1 1 1 0 ABC transporter DUF4911 PF16256.5 AJZ75555.1 - 0.03 14.3 0.0 0.097 12.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) AAA_14 PF13173.6 AJZ75555.1 - 0.047 13.7 7.3 0.53 10.3 0.0 3.3 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.6 AJZ75555.1 - 0.072 12.8 2.7 0.52 10.0 2.6 2.4 1 1 0 1 1 1 0 AAA domain Phage_HK97_TLTM PF06120.11 AJZ75555.1 - 0.082 12.1 1.1 0.87 8.7 0.9 2.3 1 1 1 2 2 2 0 Tail length tape measure protein TsaE PF02367.17 AJZ75555.1 - 0.093 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 AJZ75555.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 AJZ75555.1 - 0.1 12.1 0.2 6.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.14 AJZ75555.1 - 0.12 12.4 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MIP PF00230.20 AJZ75556.1 - 1e-53 182.4 19.3 1.4e-53 182.0 19.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3930 PF13067.6 AJZ75556.1 - 3.8 7.8 5.3 1.6 9.0 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3930) AhpC-TSA PF00578.21 AJZ75557.1 - 7.3e-41 139.0 0.3 8.4e-41 138.8 0.3 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJZ75557.1 - 8.1e-28 97.0 0.0 9.1e-28 96.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 AJZ75557.1 - 2.9e-07 30.6 0.1 5.7e-07 29.7 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 AJZ75557.1 - 8.9e-07 28.6 0.0 1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) SCO1-SenC PF02630.14 AJZ75557.1 - 1.6e-05 24.8 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC DUF3986 PF13143.6 AJZ75557.1 - 0.0089 17.0 0.2 0.016 16.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3986) FtsQ PF03799.15 AJZ75557.1 - 0.2 12.5 0.0 0.5 11.2 0.0 1.6 2 0 0 2 2 2 0 Cell division protein FtsQ ABC_tran_CTD PF16326.5 AJZ75558.1 - 0.017 15.4 0.8 0.029 14.6 0.8 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain M PF02370.16 AJZ75558.1 - 0.039 14.5 4.4 0.091 13.3 4.4 1.6 1 0 0 1 1 1 0 M protein repeat Cauli_VI PF01693.16 AJZ75558.1 - 0.12 12.7 1.6 3.1 8.2 0.3 2.3 2 0 0 2 2 2 0 Caulimovirus viroplasmin DUF2748 PF10871.8 AJZ75559.1 - 0.015 13.9 0.1 0.017 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) UbiD PF01977.16 AJZ75560.1 - 1.5e-153 511.5 0.1 1.7e-153 511.3 0.1 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF4751 PF15942.5 AJZ75560.1 - 0.062 13.2 0.1 0.44 10.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4751) Radical_SAM PF04055.21 AJZ75561.1 - 7.2e-16 59.0 0.0 1e-15 58.6 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily DUF905 PF06006.12 AJZ75561.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) DeoC PF01791.9 AJZ75562.1 - 1.2e-47 162.5 0.0 1.5e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase YjeF_N PF03853.15 AJZ75562.1 - 0.006 16.5 0.0 0.0086 16.0 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus DHQS PF01959.16 AJZ75563.1 - 1.1e-102 343.6 0.2 1.2e-102 343.4 0.2 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase II CppA_N PF14506.6 AJZ75563.1 - 0.0015 18.6 0.1 0.014 15.5 0.0 2.2 2 0 0 2 2 2 1 CppA N-terminal Prot_ATP_ID_OB PF16450.5 AJZ75563.1 - 0.044 13.7 0.1 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain DHquinase_I PF01487.15 AJZ75564.1 - 2.5e-51 175.1 0.0 2.8e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Type I 3-dehydroquinase SEFIR PF08357.11 AJZ75564.1 - 0.066 13.5 0.1 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 SEFIR domain Shikimate_dh_N PF08501.11 AJZ75565.1 - 1.6e-29 102.0 0.0 3e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 AJZ75565.1 - 1.2e-10 41.0 0.1 1.9e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 AJZ75565.1 - 2.4e-09 37.3 0.2 3.9e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AJZ75565.1 - 0.0011 19.2 0.2 0.0018 18.5 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 AJZ75565.1 - 0.01 16.4 0.1 0.017 15.7 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 AJZ75565.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GARS_N PF02844.15 AJZ75565.1 - 0.13 13.1 0.2 0.27 12.0 0.2 1.8 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain GHMP_kinases_N PF00288.26 AJZ75566.1 - 2e-08 34.3 1.0 4.4e-08 33.2 1.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AJZ75566.1 - 4.1e-06 27.1 0.0 2.5e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal VirDNA-topo-I_N PF09266.10 AJZ75566.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal EPSP_synthase PF00275.20 AJZ75567.1 - 1.2e-105 353.6 0.1 1.5e-105 353.3 0.1 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) B5 PF03484.15 AJZ75567.1 - 0.0088 16.3 0.7 4.3 7.7 0.0 3.8 4 0 0 4 4 4 1 tRNA synthetase B5 domain Chorismate_synt PF01264.21 AJZ75568.1 - 2.5e-134 447.1 0.3 2.9e-134 446.9 0.3 1.0 1 0 0 1 1 1 1 Chorismate synthase PDH PF02153.17 AJZ75569.1 - 1.7e-23 82.9 0.3 2.3e-23 82.5 0.3 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 AJZ75569.1 - 1.6e-06 28.4 0.0 6.9e-06 26.3 0.0 1.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AJZ75569.1 - 3.5e-06 27.5 0.1 6.3e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AJZ75569.1 - 2e-05 24.0 0.0 4.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AJZ75569.1 - 0.016 15.1 0.1 0.048 13.5 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 AJZ75569.1 - 0.042 14.3 0.0 0.083 13.4 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain NAD_Gly3P_dh_N PF01210.23 AJZ75569.1 - 0.3 11.1 2.0 1.3 9.0 0.0 2.7 2 2 1 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NUDIX PF00293.28 AJZ75570.1 - 1.3e-09 38.2 0.0 1.4e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain ThiC_Rad_SAM PF01964.18 AJZ75571.1 - 1.7e-173 577.3 0.5 1.9e-173 577.1 0.5 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family Plectin PF00681.20 AJZ75571.1 - 0.031 14.2 0.0 32 4.5 0.0 3.5 3 0 0 3 3 3 0 Plectin repeat CnrY PF17524.2 AJZ75571.1 - 0.14 12.4 0.0 2.3 8.5 0.0 2.6 3 0 0 3 3 3 0 Anti-sigma factor CnrY DUF3006 PF11213.8 AJZ75571.1 - 0.21 11.9 2.3 18 5.6 0.1 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF3006) Phos_pyr_kin PF08543.12 AJZ75572.1 - 1.2e-66 224.6 1.7 1.2e-66 224.6 1.7 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase ThiP_synth PF10120.9 AJZ75572.1 - 3.5e-55 186.1 0.0 8e-55 184.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine-phosphate synthase Carb_kinase PF01256.17 AJZ75572.1 - 4e-08 33.1 0.1 5.9e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate kinase PfkB PF00294.24 AJZ75572.1 - 5.3e-07 29.2 0.1 9.4e-07 28.4 0.1 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 AJZ75572.1 - 3.7e-05 23.2 0.2 8.9e-05 22.0 0.2 1.6 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family NTP_transferase PF00483.23 AJZ75573.1 - 2.1e-37 129.0 0.0 2.4e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AJZ75573.1 - 3.1e-11 43.9 0.0 3.7e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 AJZ75573.1 - 0.0018 18.3 0.0 0.0063 16.5 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase IspD PF01128.19 AJZ75573.1 - 0.0044 16.8 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Acetyltransf_1 PF00583.25 AJZ75574.1 - 4.4e-18 65.6 0.0 5.2e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AJZ75574.1 - 5.7e-15 55.4 0.1 7.4e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AJZ75574.1 - 1.1e-11 45.0 0.2 1.6e-11 44.5 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AJZ75574.1 - 7.2e-05 22.9 0.0 7.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AJZ75574.1 - 0.0012 18.9 0.2 0.0032 17.6 0.1 1.8 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 AJZ75574.1 - 0.0019 18.3 0.1 0.0028 17.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AJZ75574.1 - 0.0047 16.9 0.0 0.017 15.1 0.0 1.9 2 1 0 2 2 2 1 FR47-like protein Diacid_rec PF05651.13 AJZ75574.1 - 0.0097 15.6 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 Putative sugar diacid recognition sCache_like PF16736.5 AJZ75574.1 - 0.089 12.9 0.1 0.15 12.2 0.1 1.4 1 1 0 1 1 1 0 Single Cache-like Cas_Csx9 PF09658.10 AJZ75575.1 - 0.053 12.7 0.1 0.081 12.1 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) B12D PF06522.11 AJZ75575.1 - 0.15 11.9 0.5 5.9 6.8 0.1 2.7 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Oxidored_q2 PF00420.24 AJZ75575.1 - 0.2 11.3 2.9 0.2 11.3 0.2 2.0 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ABC2_membrane_5 PF13346.6 AJZ75575.1 - 0.62 9.6 6.1 0.89 9.1 6.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2975 PF11188.8 AJZ75575.1 - 3.1 7.7 6.9 0.71 9.8 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) DUF309 PF03745.14 AJZ75576.1 - 1.3e-19 69.6 0.7 2e-19 69.0 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF309) PFO_beta_C PF12367.8 AJZ75576.1 - 0.07 13.3 0.1 1.8 8.8 0.1 2.8 2 1 1 3 3 3 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Ribosomal_S24e PF01282.19 AJZ75577.1 - 8e-08 32.1 0.1 1.1e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S27 PF01599.19 AJZ75578.1 - 1.9e-18 66.3 5.0 2.4e-18 66.0 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27a Ribosomal_L37e PF01907.19 AJZ75578.1 - 7.1e-05 22.9 4.2 0.0001 22.4 4.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DUF1451 PF07295.11 AJZ75578.1 - 0.00064 19.8 0.9 0.00065 19.8 0.9 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain Ephrin_rec_like PF07699.13 AJZ75578.1 - 0.011 15.4 0.4 0.016 14.9 0.4 1.3 1 0 0 1 1 1 0 Putative ephrin-receptor like Nudix_N_2 PF14803.6 AJZ75578.1 - 0.023 14.6 4.6 0.12 12.3 3.8 2.2 1 1 1 2 2 2 0 Nudix N-terminal GFA PF04828.14 AJZ75578.1 - 0.034 14.5 2.9 0.22 11.9 3.0 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf_UBZ PF18439.1 AJZ75578.1 - 0.23 11.1 2.1 1.4 8.6 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 AJZ75578.1 - 0.41 10.4 5.3 6.5 6.6 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 AJZ75578.1 - 1.1 8.7 7.1 17 5.0 7.1 2.1 1 1 0 1 1 1 0 zinc-ribbon domain SprT-like PF10263.9 AJZ75579.1 - 0.088 12.7 0.1 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 SprT-like family THUMP PF02926.17 AJZ75580.1 - 1.8e-05 24.9 0.2 3.7e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 THUMP domain Rad50_zn_hook PF04423.14 AJZ75580.1 - 0.02 14.7 1.6 0.026 14.4 0.2 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif SRP54 PF00448.22 AJZ75581.1 - 5e-68 228.6 0.3 8.6e-68 227.8 0.3 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 AJZ75581.1 - 7e-26 90.8 0.5 2.4e-25 89.0 0.5 2.0 1 0 0 1 1 1 1 Signal peptide binding domain SRP54_N PF02881.19 AJZ75581.1 - 1.6e-14 53.9 3.2 1.6e-14 53.8 1.0 2.3 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 AJZ75581.1 - 3.9e-06 27.0 0.0 1.1e-05 25.5 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 AJZ75581.1 - 0.00017 20.6 0.1 0.0004 19.4 0.1 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 AJZ75581.1 - 0.00039 20.3 0.5 0.00086 19.2 0.5 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ParA PF10609.9 AJZ75581.1 - 0.00045 19.7 0.4 0.0011 18.5 0.2 1.6 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase APS_kinase PF01583.20 AJZ75581.1 - 0.0011 18.8 0.1 0.0026 17.7 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_31 PF13614.6 AJZ75581.1 - 0.0017 18.3 0.5 0.0052 16.7 0.3 1.9 2 1 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 AJZ75581.1 - 0.0028 17.7 0.3 0.014 15.5 0.3 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 AJZ75581.1 - 0.0042 16.8 1.1 1.3 8.8 0.6 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 AJZ75581.1 - 0.0046 17.4 0.3 0.018 15.4 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 AJZ75581.1 - 0.0054 17.3 0.5 0.019 15.5 0.5 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 AJZ75581.1 - 0.0075 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 AJZ75581.1 - 0.0092 15.8 0.2 0.017 14.9 0.2 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 AJZ75581.1 - 0.012 15.6 0.7 0.053 13.5 0.3 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 AJZ75581.1 - 0.015 15.3 3.7 0.025 14.5 1.3 2.4 2 1 0 2 2 2 0 NTPase AAA_17 PF13207.6 AJZ75581.1 - 0.015 15.7 1.8 0.033 14.6 0.3 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 AJZ75581.1 - 0.018 14.7 2.0 0.11 12.1 2.0 2.1 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 AJZ75581.1 - 0.024 14.4 0.1 0.055 13.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 AJZ75581.1 - 0.027 14.1 0.9 0.09 12.4 0.9 1.8 1 0 0 1 1 1 0 Thymidylate kinase LpxK PF02606.14 AJZ75581.1 - 0.03 13.4 0.2 0.048 12.7 0.2 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase 6PF2K PF01591.18 AJZ75581.1 - 0.034 13.5 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_7 PF12775.7 AJZ75581.1 - 0.046 13.2 0.1 0.086 12.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 AJZ75581.1 - 0.057 12.6 0.0 0.095 11.8 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Zeta_toxin PF06414.12 AJZ75581.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin VirC1 PF07015.11 AJZ75581.1 - 0.076 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein ABC_tran PF00005.27 AJZ75581.1 - 0.078 13.5 0.2 0.32 11.5 0.1 2.0 2 0 0 2 2 2 0 ABC transporter MipZ PF09140.11 AJZ75581.1 - 0.086 12.1 0.4 1.8 7.8 0.4 2.2 1 1 0 1 1 1 0 ATPase MipZ AAA_33 PF13671.6 AJZ75581.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AJZ75581.1 - 0.16 12.4 0.6 0.65 10.4 0.1 2.4 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 AJZ75581.1 - 0.23 10.9 1.4 1.6 8.1 0.4 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Diphthami_syn_2 PF01902.17 AJZ75582.1 - 5e-57 192.9 0.1 5.7e-57 192.7 0.1 1.0 1 0 0 1 1 1 1 Diphthamide synthase QueC PF06508.13 AJZ75582.1 - 0.0073 15.8 0.2 0.017 14.6 0.1 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 AJZ75582.1 - 0.068 12.0 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase eIF-5a PF01287.20 AJZ75583.1 - 1.9e-09 37.5 2.7 2.6e-09 37.0 2.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 AJZ75583.1 - 0.0089 16.0 0.0 0.075 13.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 AJZ75583.1 - 0.075 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain HTH_AsnC-type PF13404.6 AJZ75584.1 - 4.4e-08 32.8 1.3 3e-07 30.1 1.3 2.2 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AJZ75584.1 - 7.3e-08 31.8 2.0 0.005 16.4 0.2 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_12 PF08461.10 AJZ75584.1 - 5e-06 26.4 1.2 9.1e-06 25.5 0.4 1.9 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain HTH_11 PF08279.12 AJZ75584.1 - 6.1e-05 22.9 0.3 0.00021 21.2 0.3 1.9 1 1 0 1 1 1 1 HTH domain HTH_Tnp_Tc3_2 PF01498.18 AJZ75584.1 - 0.00032 20.9 0.2 0.00058 20.1 0.2 1.4 1 0 0 1 1 1 1 Transposase Penicillinase_R PF03965.16 AJZ75584.1 - 0.0012 19.2 0.1 0.0023 18.3 0.1 1.5 1 0 0 1 1 1 1 Penicillinase repressor HTH_20 PF12840.7 AJZ75584.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_DeoR PF08220.12 AJZ75584.1 - 0.028 14.1 0.3 0.06 13.1 0.3 1.6 1 1 0 1 1 1 0 DeoR-like helix-turn-helix domain Nuc_N PF14448.6 AJZ75584.1 - 0.054 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Nuclease N terminal DUF3369 PF11849.8 AJZ75584.1 - 0.066 13.4 0.1 1.1 9.4 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3369) Myb_DNA-bind_4 PF13837.6 AJZ75584.1 - 0.074 13.4 0.1 0.14 12.6 0.1 1.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain FUR PF01475.19 AJZ75584.1 - 0.074 13.2 0.4 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Ferric uptake regulator family DUF3658 PF12395.8 AJZ75584.1 - 0.091 12.7 0.2 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function Response_reg PF00072.24 AJZ75585.1 - 2.1e-15 56.9 0.9 3.6e-15 56.1 0.3 1.7 2 0 0 2 2 2 1 Response regulator receiver domain DUF627 PF04781.12 AJZ75585.1 - 0.0065 16.5 1.0 0.013 15.5 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF627) ANAPC3 PF12895.7 AJZ75585.1 - 0.011 16.0 6.0 0.1 12.8 2.5 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 AJZ75585.1 - 0.018 15.1 0.3 0.071 13.3 0.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 AJZ75585.1 - 0.029 14.2 0.5 0.029 14.2 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PK_C PF02887.16 AJZ75585.1 - 0.076 13.3 0.3 0.29 11.4 0.0 1.9 2 1 0 2 2 2 0 Pyruvate kinase, alpha/beta domain TPR_6 PF13174.6 AJZ75585.1 - 0.091 13.4 0.1 0.4 11.4 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_21 PF09976.9 AJZ75585.1 - 0.19 11.4 4.1 0.41 10.3 4.0 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain PHO4 PF01384.20 AJZ75586.1 - 1.4e-84 284.0 41.4 8e-84 281.5 41.4 1.8 1 1 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.10 AJZ75586.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Myc_target_1 PF15179.6 AJZ75586.1 - 0.27 11.1 4.8 0.38 10.6 0.8 2.1 2 0 0 2 2 2 0 Myc target protein 1 PhoU_div PF01865.16 AJZ75587.1 - 1.3e-28 99.8 11.0 1.5e-28 99.6 11.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 Vps5 PF09325.10 AJZ75587.1 - 0.00098 18.7 1.6 0.64 9.5 0.0 2.6 2 1 1 3 3 3 2 Vps5 C terminal like ArAE_1_C PF11728.8 AJZ75587.1 - 0.0059 16.6 1.4 0.035 14.1 0.2 2.6 1 1 0 1 1 1 1 Putative aromatic acid exporter C-terminal domain ACCA PF03255.14 AJZ75587.1 - 0.0065 16.4 3.2 0.018 14.9 0.4 2.1 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Lzipper-MIP1 PF14389.6 AJZ75587.1 - 0.0067 16.7 0.7 9.5 6.6 0.1 3.3 3 1 0 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 Sec2p PF06428.11 AJZ75587.1 - 0.012 15.5 3.2 0.013 15.5 0.6 2.4 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p INTS5_C PF14838.6 AJZ75587.1 - 0.023 13.4 0.5 0.023 13.3 0.5 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus PIN_12 PF16289.5 AJZ75587.1 - 0.05 14.1 7.5 0.17 12.4 0.5 2.2 2 0 0 2 2 2 0 PIN domain CENP-R PF06729.12 AJZ75587.1 - 0.11 12.4 0.4 0.24 11.4 0.4 1.5 1 0 0 1 1 1 0 Kinetochore component, CENP-R TFIID-31kDa PF02291.15 AJZ75587.1 - 0.22 11.6 1.5 0.57 10.3 0.3 2.1 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF2130 PF09903.9 AJZ75587.1 - 0.23 10.7 7.1 0.5 9.6 2.8 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) YgaB PF14182.6 AJZ75587.1 - 0.41 11.1 3.5 0.4 11.1 0.3 2.6 2 1 0 2 2 2 0 YgaB-like protein Endotoxin_C2 PF18449.1 AJZ75587.1 - 0.44 10.9 4.5 8.5 6.8 0.9 3.0 3 0 0 3 3 3 0 Delta endotoxin P-II PF00543.22 AJZ75588.1 - 9e-21 74.4 1.3 1e-20 74.2 1.3 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II P-II PF00543.22 AJZ75589.1 - 8e-10 39.2 1.0 1.6e-09 38.3 0.9 1.5 2 0 0 2 2 2 1 Nitrogen regulatory protein P-II ADH_N PF08240.12 AJZ75590.1 - 7.2e-35 119.2 1.1 1.2e-34 118.5 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AJZ75590.1 - 3.2e-29 101.6 0.2 5.1e-29 100.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AJZ75590.1 - 5.9e-11 43.6 0.0 9e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AJZ75590.1 - 3.5e-07 29.9 0.2 8.4e-07 28.7 0.2 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Methyltransf_16 PF10294.9 AJZ75590.1 - 0.0063 16.3 0.2 0.01 15.6 0.2 1.2 1 0 0 1 1 1 1 Lysine methyltransferase DapB_N PF01113.20 AJZ75590.1 - 0.0092 16.1 0.4 0.018 15.2 0.4 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 AJZ75590.1 - 0.017 15.4 0.1 0.037 14.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain PglD_N PF17836.1 AJZ75590.1 - 0.045 14.4 1.3 0.066 13.9 0.4 1.8 2 0 0 2 2 2 0 PglD N-terminal domain NAD_binding_2 PF03446.15 AJZ75590.1 - 0.057 13.6 0.2 0.088 13.0 0.2 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 AJZ75590.1 - 0.11 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MTS PF05175.14 AJZ75590.1 - 0.11 12.0 0.2 0.18 11.3 0.2 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Malic_M PF03949.15 AJZ75590.1 - 0.12 11.6 2.7 1.2 8.4 1.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain SMC_ScpA PF02616.14 AJZ75591.1 - 1.6e-06 28.2 2.8 0.0024 17.9 0.1 2.2 2 0 0 2 2 2 2 Segregation and condensation protein ScpA SMC_ScpB PF04079.16 AJZ75592.1 - 2.8e-33 114.8 0.3 3.2e-33 114.6 0.3 1.0 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB HHH_3 PF12836.7 AJZ75592.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif RestrictionSfiI PF11487.8 AJZ75592.1 - 0.061 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme SfiI HTH_20 PF12840.7 AJZ75592.1 - 0.075 13.1 0.1 0.61 10.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_S8e PF01201.22 AJZ75593.1 - 2.6e-19 69.8 2.9 3e-19 69.6 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SRP19 PF01922.17 AJZ75594.1 - 2.7e-13 50.7 0.0 3.2e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein TFIIB PF00382.19 AJZ75595.1 - 2.8e-26 91.4 2.2 2.6e-12 46.6 0.2 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJZ75595.1 - 1.4e-08 34.1 2.4 1.4e-08 34.1 2.4 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.23 AJZ75595.1 - 0.009 15.8 0.7 0.025 14.3 0.2 1.9 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 AJZ75595.1 - 0.045 13.8 0.1 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 Cyclin, C-terminal domain DUF3566 PF12089.8 AJZ75595.1 - 0.064 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) ABC_tran PF00005.27 AJZ75596.1 - 4.4e-21 75.8 0.0 6.6e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AJZ75596.1 - 6.3e-10 39.3 0.1 0.0003 20.7 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AJZ75596.1 - 1.2e-09 38.0 0.3 1.7e-08 34.2 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AJZ75596.1 - 0.001 18.8 0.7 0.002 17.8 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AJZ75596.1 - 0.0066 16.1 0.1 0.038 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 AJZ75596.1 - 0.0071 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AJZ75596.1 - 0.0078 16.4 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AJZ75596.1 - 0.019 14.7 0.2 0.045 13.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AJZ75596.1 - 0.022 15.3 0.9 0.046 14.2 0.8 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AJZ75596.1 - 0.029 14.7 0.0 0.61 10.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 AJZ75596.1 - 0.032 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 AJZ75596.1 - 0.034 12.8 0.8 1.1 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AJZ75596.1 - 0.036 14.5 0.4 0.76 10.2 0.4 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 AJZ75596.1 - 0.043 13.7 0.1 0.11 12.4 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AJZ75596.1 - 0.077 13.3 0.2 0.24 11.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AJZ75596.1 - 0.088 13.2 0.1 0.32 11.4 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 AJZ75596.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_15 PF13175.6 AJZ75596.1 - 0.12 12.1 0.1 0.4 10.3 0.0 1.7 1 1 0 2 2 2 0 AAA ATPase domain DUF167 PF02594.16 AJZ75597.1 - 1.3e-14 54.0 0.2 1.5e-14 53.8 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 HTH_50 PF18024.1 AJZ75597.1 - 0.059 13.0 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Chlor_dismutase PF06778.12 AJZ75598.1 - 1.8e-56 190.9 0.2 2.2e-56 190.5 0.2 1.0 1 0 0 1 1 1 1 Chlorite dismutase Darcynin PF17074.5 AJZ75598.1 - 0.11 12.7 0.8 0.3 11.3 0.2 2.0 2 1 0 2 2 2 0 Darcynin, domain of unknown function Aldo_ket_red PF00248.21 AJZ75599.1 - 5.5e-51 173.5 0.0 6.2e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DNAPolymera_Pol PF11590.8 AJZ75599.1 - 0.036 13.9 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol Leuk-A4-hydro_C PF09127.11 AJZ75600.1 - 0.098 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Vac_Fusion PF02346.16 AJZ75600.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 AsnC_trans_reg2 PF17805.1 AJZ75602.1 - 8.7e-52 173.2 0.0 1.3e-28 98.9 0.0 2.6 3 0 0 3 3 3 2 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AJZ75602.1 - 3.6e-05 23.5 0.0 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 AJZ75602.1 - 0.004 17.1 0.0 4.9 7.2 0.0 3.1 2 1 0 2 2 2 2 Lrp/AsnC ligand binding domain NapD PF03927.13 AJZ75602.1 - 0.011 15.7 0.0 0.056 13.5 0.0 2.0 2 0 0 2 2 2 0 NapD protein HTH_24 PF13412.6 AJZ75602.1 - 0.097 12.3 0.2 1.7 8.3 0.2 2.4 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding GlutR_N PF05201.15 AJZ75603.1 - 4.4e-39 133.6 0.1 9.5e-39 132.5 0.1 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 AJZ75603.1 - 3.6e-29 101.6 1.0 5.3e-29 101.0 0.1 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 AJZ75603.1 - 9.8e-19 67.6 2.2 2.2e-18 66.5 2.2 1.7 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 AJZ75603.1 - 2.5e-05 24.7 0.0 8.4e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AJZ75603.1 - 0.0028 17.0 0.0 0.0067 15.8 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Malic_M PF03949.15 AJZ75603.1 - 0.067 12.5 0.1 3.6 6.8 0.1 2.3 1 1 1 2 2 2 0 Malic enzyme, NAD binding domain ALAD PF00490.21 AJZ75604.1 - 2e-135 451.1 0.3 2.2e-135 450.9 0.3 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF2674 PF10879.8 AJZ75604.1 - 0.02 14.4 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) ATP19 PF11022.8 AJZ75605.1 - 0.097 13.0 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase subunit K DUF2371 PF10177.9 AJZ75607.1 - 0.0051 17.0 1.0 0.017 15.3 0.6 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2371) Neurensin PF14927.6 AJZ75607.1 - 0.0086 15.8 0.2 0.043 13.5 0.0 2.0 2 0 0 2 2 2 1 Neurensin Saf_2TM PF18303.1 AJZ75607.1 - 0.0099 15.5 2.2 0.012 15.2 0.8 1.8 2 0 0 2 2 2 1 SAVED-fused 2TM effector domain DUF2207 PF09972.9 AJZ75607.1 - 0.05 12.4 0.5 0.074 11.8 0.1 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 AJZ75607.1 - 0.22 11.4 2.1 0.46 10.4 2.0 1.6 1 1 1 2 2 2 0 TMEM154 protein family DUF5385 PF17359.2 AJZ75607.1 - 0.95 9.0 3.8 1.7 8.2 3.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Pilin_N PF07790.11 AJZ75607.1 - 1.1 10.2 4.6 2.3 9.2 1.8 2.5 3 0 0 3 3 3 0 Archaeal Type IV pilin, N-terminal DUF3185 PF11381.8 AJZ75607.1 - 1.4 8.9 9.7 0.65 10.0 3.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) PAP2 PF01569.21 AJZ75609.1 - 2.2e-18 66.3 0.3 2.2e-18 66.3 0.3 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AJZ75609.1 - 4.5e-09 36.3 3.9 4.5e-09 36.3 3.9 2.2 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 AJZ75609.1 - 9.1e-06 26.1 4.5 1.2e-05 25.7 0.1 2.8 3 0 0 3 3 3 1 PAP2 superfamily C-terminal DUF212 PF02681.14 AJZ75609.1 - 0.078 13.1 0.4 7.4 6.7 0.1 2.4 1 1 1 2 2 2 0 Divergent PAP2 family TAD2 PF18521.1 AJZ75610.1 - 0.42 10.7 2.4 0.59 10.2 0.0 2.3 2 1 0 2 2 2 0 Transactivation domain 2 NifU_N PF01592.16 AJZ75611.1 - 1.9e-27 95.9 0.0 2.2e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain SufE PF02657.15 AJZ75611.1 - 0.062 13.2 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Fe-S metabolism associated domain Aminotran_5 PF00266.19 AJZ75612.1 - 5.4e-149 496.2 1.4 6.1e-149 496.0 1.4 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AJZ75612.1 - 0.0002 20.0 0.0 0.00034 19.3 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AJZ75612.1 - 0.00049 19.5 0.2 0.00079 18.8 0.2 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.13 AJZ75612.1 - 0.00064 18.8 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Alpha-amylase PF00128.24 AJZ75612.1 - 0.0079 15.8 0.8 2.1 7.8 0.0 2.8 3 0 0 3 3 3 2 Alpha amylase, catalytic domain Rieske PF00355.26 AJZ75613.1 - 1.7e-17 63.1 0.0 2e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AJZ75613.1 - 5.2e-11 42.4 0.0 6e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0051 PF01458.17 AJZ75614.1 - 1.9e-53 181.4 0.7 2.4e-53 181.0 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF5001 PF16392.5 AJZ75614.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Ig-like domain UPF0051 PF01458.17 AJZ75615.1 - 7.8e-73 244.8 0.1 1e-72 244.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) HEM4 PF02602.15 AJZ75616.1 - 1e-44 152.7 0.0 1.1e-44 152.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD YIEGIA PF14045.6 AJZ75616.1 - 0.02 13.7 0.0 0.1 11.4 0.0 1.9 2 0 0 2 2 2 0 YIEGIA protein DUF498 PF04430.14 AJZ75616.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) TP_methylase PF00590.20 AJZ75617.1 - 4.8e-45 154.1 0.0 5.5e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Porphobil_deam PF01379.20 AJZ75618.1 - 1.9e-70 236.5 0.0 2.5e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 AJZ75618.1 - 2.5e-10 40.6 0.0 5.8e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain 30K_MP_core PF17644.1 AJZ75618.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Core domain of 30K viral movement proteins Aminotran_3 PF00202.21 AJZ75619.1 - 2.8e-71 240.3 0.2 3.7e-71 239.9 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ABC2_membrane PF01061.24 AJZ75620.1 - 5e-34 117.6 20.5 5e-34 117.6 20.5 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AJZ75620.1 - 4.5e-17 62.2 29.1 5.8e-17 61.8 29.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 AJZ75621.1 - 1.3e-30 106.7 0.0 5.5e-30 104.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AJZ75621.1 - 5.4e-10 39.6 3.3 3.1e-06 27.2 0.1 2.6 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 AJZ75621.1 - 3e-06 27.9 0.0 9.6e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 AJZ75621.1 - 7.8e-05 22.5 0.7 0.069 12.8 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AJZ75621.1 - 0.0003 20.5 0.1 0.00069 19.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AJZ75621.1 - 0.0077 15.7 0.2 0.71 9.3 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AJZ75621.1 - 0.021 15.3 4.5 0.043 14.3 4.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AJZ75621.1 - 0.024 14.4 0.0 0.06 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 AJZ75621.1 - 0.084 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Thymidylate_kin PF02223.17 AJZ75621.1 - 0.092 12.4 0.1 0.17 11.5 0.1 1.6 1 1 0 1 1 1 0 Thymidylate kinase F420H2_quin_red PF04075.14 AJZ75622.1 - 1.3e-05 25.3 0.1 1.6e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DUF2255 PF10012.9 AJZ75622.1 - 0.04 14.1 0.4 0.048 13.8 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) HTH_Tnp_Tc5 PF03221.16 AJZ75623.1 - 0.0029 17.6 0.1 0.005 16.8 0.1 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3211 PF11485.8 AJZ75625.1 - 0.04 14.1 0.0 3.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3211) Acetyltransf_1 PF00583.25 AJZ75626.1 - 1e-12 48.3 0.0 1.2e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AJZ75626.1 - 3.3e-11 43.5 0.0 4.2e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AJZ75626.1 - 1.4e-10 41.1 0.1 1.9e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AJZ75626.1 - 8.8e-05 22.7 0.0 0.0001 22.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AJZ75626.1 - 0.00099 18.8 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 AJZ75626.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 AJZ75626.1 - 0.052 13.0 1.4 0.15 11.5 1.4 1.7 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 AJZ75626.1 - 0.08 13.1 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PLDc_2 PF13091.6 AJZ75627.1 - 2.8e-05 24.0 0.1 3.7e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 PLD-like domain tRNA_int_endo PF01974.17 AJZ75628.1 - 2.2e-19 69.3 0.1 3.8e-19 68.5 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 AJZ75628.1 - 4.2e-12 45.6 2.7 7.4e-11 41.6 0.3 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Sigma70_r3 PF04539.16 AJZ75629.1 - 0.018 15.1 0.0 0.05 13.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-70 region 3 JmjN PF02375.17 AJZ75629.1 - 0.2 11.7 0.5 1.6 8.8 0.1 2.3 2 1 0 2 2 2 0 jmjN domain Na_H_Exchanger PF00999.21 AJZ75631.1 - 2.6e-53 181.2 57.1 3.3e-53 180.9 57.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Spore_YabQ PF09578.10 AJZ75631.1 - 0.014 15.6 0.1 0.014 15.6 0.1 4.7 5 2 0 6 6 6 0 Spore cortex protein YabQ (Spore_YabQ) DUF2791 PF10923.8 AJZ75632.1 - 0.0064 15.4 0.1 0.012 14.5 0.1 1.4 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) AAA_22 PF13401.6 AJZ75632.1 - 0.012 15.8 0.2 0.66 10.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 AJZ75632.1 - 0.087 12.7 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Kre28 PF17097.5 AJZ75633.1 - 0.0022 17.0 0.2 0.0037 16.3 0.2 1.3 1 0 0 1 1 1 1 Spindle pole body component DUF5374 PF17344.2 AJZ75633.1 - 0.0099 15.8 1.2 22 5.1 0.1 4.1 4 0 0 4 4 4 1 Family of unknown function (DUF5374) TFA2_Winged_2 PF18121.1 AJZ75633.1 - 0.14 11.9 0.6 0.37 10.5 0.3 2.0 2 1 0 2 2 2 0 TFA2 Winged helix domain 2 DUF1664 PF07889.12 AJZ75635.1 - 0.00027 21.0 33.2 0.0011 19.0 0.4 4.9 2 1 3 5 5 5 3 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 AJZ75635.1 - 0.00054 20.2 0.4 0.00054 20.2 0.4 5.1 2 2 3 5 5 5 1 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 AJZ75635.1 - 0.0032 17.5 42.3 0.0049 16.9 1.7 4.5 2 1 3 5 5 5 3 Laminin Domain II DUF4164 PF13747.6 AJZ75635.1 - 0.013 15.8 13.2 0.018 15.3 2.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) Sec34 PF04136.15 AJZ75635.1 - 0.029 14.2 1.2 0.029 14.2 1.2 5.2 3 1 2 5 5 5 0 Sec34-like family ABC_tran_CTD PF16326.5 AJZ75635.1 - 0.078 13.2 0.6 0.078 13.2 0.6 4.9 3 2 1 4 4 4 0 ABC transporter C-terminal domain Cauli_AT PF03233.13 AJZ75635.1 - 0.21 11.5 34.4 0.024 14.6 4.5 4.7 1 1 3 5 5 5 0 Aphid transmission protein eIF3_N PF09440.10 AJZ75635.1 - 0.32 11.4 24.7 0.99 9.8 1.4 4.7 1 1 3 5 5 5 0 eIF3 subunit 6 N terminal domain Cob_adeno_trans PF01923.18 AJZ75635.1 - 0.32 11.1 12.8 0.32 11.1 0.2 3.8 1 1 2 3 3 3 0 Cobalamin adenosyltransferase DUF948 PF06103.11 AJZ75635.1 - 0.5 10.6 25.3 2.6 8.4 0.6 5.9 2 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) TBCA PF02970.16 AJZ75635.1 - 1 9.8 17.6 0.5 10.7 1.8 3.9 3 1 0 4 4 4 0 Tubulin binding cofactor A Mod_r PF07200.13 AJZ75635.1 - 1.7 8.8 28.6 0.94 9.6 1.6 4.4 1 1 4 5 5 5 0 Modifier of rudimentary (Mod(r)) protein IL6 PF00489.17 AJZ75635.1 - 2.2 7.8 14.9 0.12 12.0 0.6 3.7 2 1 0 3 3 3 0 Interleukin-6/G-CSF/MGF family CCDC-167 PF15188.6 AJZ75635.1 - 2.4 8.5 20.4 19 5.7 11.2 4.6 2 1 3 5 5 5 0 Coiled-coil domain-containing protein 167 SKA2 PF16740.5 AJZ75635.1 - 3.9 7.3 29.8 0.31 10.8 2.0 5.4 4 1 2 6 6 6 0 Spindle and kinetochore-associated protein 2 DUF3450 PF11932.8 AJZ75635.1 - 4.8 6.4 30.9 0.52 9.6 3.3 4.2 2 1 1 4 4 4 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 AJZ75635.1 - 5.4 7.6 32.9 13 6.3 6.3 6.0 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein VWA_2 PF13519.6 AJZ75635.1 - 8 7.2 9.3 20 5.9 0.2 3.5 1 1 2 4 4 4 0 von Willebrand factor type A domain Fib_alpha PF08702.10 AJZ75635.1 - 9.1 6.5 39.7 3.7 7.7 3.4 4.3 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family MCPsignal PF00015.21 AJZ75636.1 - 2.2e-40 138.3 54.9 7.2e-40 136.6 22.5 4.2 1 1 3 4 4 4 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AJZ75636.1 - 1.8e-09 37.9 6.1 1.3e-07 31.8 0.0 4.3 5 1 0 5 5 5 2 HAMP domain PhageMin_Tail PF10145.9 AJZ75636.1 - 0.0011 18.8 25.8 0.027 14.3 10.3 3.4 1 1 2 3 3 3 2 Phage-related minor tail protein DUF745 PF05335.13 AJZ75636.1 - 0.0016 18.2 5.1 0.0016 18.2 5.1 3.6 2 1 0 2 2 2 1 Protein of unknown function (DUF745) DUF948 PF06103.11 AJZ75636.1 - 0.013 15.7 33.7 0.37 11.1 1.7 5.7 2 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 AJZ75636.1 - 0.38 10.8 38.7 0.13 12.3 4.4 4.3 1 1 3 4 4 4 0 Laminin Domain II DUF5434 PF17502.2 AJZ75636.1 - 0.99 9.4 8.1 6 6.8 2.4 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5434) BLOC1_2 PF10046.9 AJZ75636.1 - 1.6 9.1 35.2 1.7 9.0 0.5 6.1 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0242 PF06785.11 AJZ75636.1 - 6.1 6.9 23.6 0.92 9.6 1.6 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus KxDL PF10241.9 AJZ75636.1 - 9.7 6.6 18.6 1.2 9.5 0.9 4.3 3 1 2 5 5 5 0 Uncharacterized conserved protein Glyco_tranf_2_3 PF13641.6 AJZ75637.1 - 1.3e-25 90.7 0.0 2e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AJZ75637.1 - 1.1e-21 77.6 0.8 1.1e-21 77.6 0.8 2.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 AJZ75637.1 - 4.7e-19 68.8 0.1 8.7e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AJZ75637.1 - 2.2e-12 46.8 0.2 3.7e-12 46.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 AJZ75637.1 - 0.0034 16.0 2.0 0.033 12.7 0.3 2.1 2 0 0 2 2 2 1 Cellulose synthase Glyco_tranf_2_4 PF13704.6 AJZ75637.1 - 0.019 15.4 0.6 0.081 13.4 0.3 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF4234 PF14018.6 AJZ75637.1 - 0.023 14.8 0.5 2.4 8.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Fer4 PF00037.27 AJZ75638.1 - 2.8e-08 33.2 15.4 8e-05 22.3 2.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJZ75638.1 - 7.5e-06 26.5 5.7 3.1e-05 24.5 6.3 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJZ75638.1 - 1.7e-05 24.9 4.7 3.1e-05 24.0 4.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJZ75638.1 - 0.00024 21.1 7.5 0.00068 19.7 7.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Tenui_PVC2 PF06656.11 AJZ75638.1 - 0.00083 17.4 0.1 0.0011 17.0 0.1 1.1 1 0 0 1 1 1 1 Tenuivirus PVC2 protein ETF_QO PF05187.13 AJZ75638.1 - 0.0018 18.4 0.3 0.0041 17.2 0.3 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_6 PF12837.7 AJZ75638.1 - 0.0019 18.2 2.7 0.0019 18.2 2.7 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 AJZ75638.1 - 0.0026 17.8 6.5 0.0063 16.6 6.5 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AJZ75638.1 - 0.079 13.9 9.1 2.9 8.9 2.7 2.6 1 1 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AJZ75638.1 - 0.36 11.0 11.1 0.33 11.2 0.8 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 AJZ75638.1 - 0.38 11.3 6.1 2.3 8.7 6.4 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AJZ75638.1 - 2 9.1 7.5 5.4 7.8 0.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 AJZ75638.1 - 5.4 7.6 7.1 55 4.4 0.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AJZ75638.1 - 6.6 7.9 14.8 11 7.2 5.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain NAD_binding_1 PF00175.21 AJZ75639.1 - 1.3e-11 45.1 0.0 2.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AJZ75639.1 - 1.4e-07 31.7 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AJZ75639.1 - 0.013 15.6 0.1 0.033 14.3 0.1 1.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Methyltransf_34 PF11312.8 AJZ75639.1 - 0.18 11.0 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase TSNAXIP1_N PF15739.5 AJZ75640.1 - 0.034 14.5 2.1 0.2 12.1 0.9 2.3 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus APG6_N PF17675.1 AJZ75640.1 - 0.84 10.2 10.2 1 9.9 0.0 2.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Fer4 PF00037.27 AJZ75641.1 - 3.9e-08 32.8 15.2 0.00012 21.8 2.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJZ75641.1 - 1.7e-05 25.3 6.1 9.3e-05 22.9 6.8 1.8 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJZ75641.1 - 1.8e-05 24.8 4.5 3.1e-05 24.0 4.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJZ75641.1 - 0.00021 21.3 7.0 0.00058 19.9 7.0 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJZ75641.1 - 0.00038 20.5 4.7 0.0007 19.7 4.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain ETF_QO PF05187.13 AJZ75641.1 - 0.0026 17.9 0.3 0.0049 17.0 0.3 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_6 PF12837.7 AJZ75641.1 - 0.0064 16.5 2.5 0.0064 16.5 2.5 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Tenui_PVC2 PF06656.11 AJZ75641.1 - 0.0074 14.2 0.1 0.0097 13.9 0.1 1.1 1 0 0 1 1 1 1 Tenuivirus PVC2 protein Fer4_16 PF13484.6 AJZ75641.1 - 0.076 14.0 8.8 2.7 9.0 2.6 2.8 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AJZ75641.1 - 0.34 11.1 11.1 0.33 11.2 0.8 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 AJZ75641.1 - 0.56 10.7 6.7 6.5 7.3 7.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AJZ75641.1 - 2 9.1 6.8 6.7 7.5 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 AJZ75641.1 - 2.9 8.5 6.4 42 4.8 0.1 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AJZ75641.1 - 4.6 8.4 14.5 11 7.2 5.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain NAD_kinase PF01513.21 AJZ75643.1 - 2.5e-32 112.3 0.8 5.1e-32 111.2 0.8 1.5 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AJZ75643.1 - 6.3e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain BTB_2 PF02214.22 AJZ75643.1 - 0.01 16.2 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CoA_binding_2 PF13380.6 AJZ75643.1 - 0.043 14.3 0.0 0.09 13.3 0.0 1.6 1 1 0 1 1 1 0 CoA binding domain PIN_6 PF17146.4 AJZ75644.1 - 1.7e-13 50.9 0.1 2.5e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 PIN domain of ribonuclease PIN_5 PF08745.11 AJZ75644.1 - 4.1e-05 23.1 0.2 0.00012 21.6 0.1 1.7 2 0 0 2 2 2 1 PINc domain ribonuclease NOB1_Zn_bind PF08772.11 AJZ75644.1 - 9.7e-05 22.5 0.6 0.00017 21.7 0.6 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zinc-ribbons_6 PF07191.12 AJZ75644.1 - 0.0055 16.6 0.1 0.0089 16.0 0.1 1.3 1 0 0 1 1 1 1 zinc-ribbons Nudix_N_2 PF14803.6 AJZ75644.1 - 0.012 15.5 2.3 0.014 15.3 0.0 2.1 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_11 PF11682.8 AJZ75644.1 - 0.015 15.3 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon zinc_ribbon_2 PF13240.6 AJZ75644.1 - 0.016 14.9 0.8 0.037 13.8 0.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF1272 PF06906.11 AJZ75644.1 - 0.016 15.3 0.6 0.026 14.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_ribbon_SprT PF17283.2 AJZ75644.1 - 0.029 14.3 1.5 3.9 7.5 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-ribbon_3 PF13248.6 AJZ75644.1 - 0.035 13.5 0.1 0.07 12.6 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain PIN PF01850.21 AJZ75644.1 - 0.039 14.4 0.2 0.052 14.1 0.2 1.2 1 0 0 1 1 1 0 PIN domain Sar8_2 PF03058.14 AJZ75644.1 - 0.14 12.8 0.2 0.18 12.3 0.2 1.2 1 0 0 1 1 1 0 Sar8.2 family zf-LITAF-like PF10601.9 AJZ75644.1 - 0.35 11.2 2.9 14 6.0 2.9 2.3 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain Rhodanese PF00581.20 AJZ75645.1 - 1.2e-38 131.9 0.0 1.7e-19 70.3 0.0 2.0 2 0 0 2 2 2 2 Rhodanese-like domain PRR22 PF15776.5 AJZ75645.1 - 0.18 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Proline-rich protein family 22 ERCC4 PF02732.15 AJZ75646.1 - 5.2e-26 91.7 0.0 7.6e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 AJZ75646.1 - 1.7e-08 34.9 0.3 7.6e-08 32.8 0.3 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 AJZ75646.1 - 4.9e-07 29.3 0.2 0.017 15.0 0.1 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_2 PF12826.7 AJZ75646.1 - 4.2e-06 26.8 0.0 2.6e-05 24.2 0.0 2.2 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_3 PF12836.7 AJZ75646.1 - 0.00041 20.6 0.1 0.24 11.7 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_8 PF14716.6 AJZ75646.1 - 0.00083 19.7 0.3 0.14 12.5 0.2 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix domain IMS_HHH PF11798.8 AJZ75646.1 - 0.028 14.8 0.5 0.63 10.5 0.0 2.7 3 0 0 3 3 3 0 IMS family HHH motif DUF3701 PF12482.8 AJZ75646.1 - 0.034 14.2 0.1 1.5 8.9 0.0 2.3 1 1 1 2 2 2 0 Phage integrase protein Transposase_20 PF02371.16 AJZ75646.1 - 0.047 14.0 0.0 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family 5_3_exonuc PF01367.20 AJZ75646.1 - 0.079 13.6 0.1 0.27 11.9 0.1 1.9 1 1 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Prefoldin_2 PF01920.20 AJZ75647.1 - 1.6e-21 76.2 17.6 1.8e-21 76.0 17.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit SBP_bac_3 PF00497.20 AJZ75647.1 - 0.012 15.1 0.6 0.014 14.9 0.6 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DUF3053 PF11254.8 AJZ75647.1 - 0.022 14.3 3.2 0.028 14.0 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) DUF1451 PF07295.11 AJZ75647.1 - 0.056 13.5 0.3 0.056 13.5 0.3 1.8 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF4404 PF14357.6 AJZ75647.1 - 0.69 10.6 8.9 3.1 8.5 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TPR_22 PF18833.1 AJZ75647.1 - 2.2 8.5 6.6 0.6 10.3 1.1 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DivIC PF04977.15 AJZ75647.1 - 9.2 6.1 12.0 1.4 8.8 3.0 2.2 2 0 0 2 2 2 0 Septum formation initiator Pcc1 PF09341.10 AJZ75648.1 - 1.7e-08 34.4 0.1 1.9e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 UPF0262 PF06793.12 AJZ75648.1 - 0.0082 16.3 0.1 0.0092 16.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0262) Ribosomal_L37ae PF01780.19 AJZ75649.1 - 8.2e-16 57.9 3.4 8.6e-16 57.8 3.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.22 AJZ75649.1 - 0.00064 19.6 2.1 0.00084 19.2 2.1 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS1595 PF12760.7 AJZ75649.1 - 0.0045 16.9 1.8 0.0045 16.9 1.8 1.9 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 AJZ75649.1 - 0.028 13.8 2.5 2.4 7.7 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-RanBP PF00641.18 AJZ75649.1 - 0.03 13.6 4.3 1.7 8.0 0.2 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DNA_RNApol_7kD PF03604.13 AJZ75649.1 - 0.032 13.9 1.8 1 9.1 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 AJZ75649.1 - 0.061 13.1 4.1 1.3 8.9 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_13 PF17977.1 AJZ75649.1 - 0.061 13.5 0.9 0.075 13.2 0.9 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-tcix PF14952.6 AJZ75649.1 - 0.078 12.6 3.2 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-C2H2_3 PF13878.6 AJZ75649.1 - 0.092 12.6 0.9 3 7.7 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO RNA_POL_M_15KD PF02150.16 AJZ75649.1 - 0.15 12.0 2.7 0.54 10.2 2.5 1.9 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit HalOD2 PF18547.1 AJZ75649.1 - 2.3 8.2 6.8 9.3 6.2 1.3 2.2 1 1 1 2 2 2 0 Halobacterial output domain 2 zn-ribbon_14 PF16503.5 AJZ75649.1 - 2.3 7.8 8.3 8.3 6.0 0.7 2.4 2 0 0 2 2 2 0 Zinc-ribbon RNase_PH PF01138.21 AJZ75650.1 - 4.4e-24 85.5 0.0 8.1e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AJZ75650.1 - 6.9e-17 61.2 0.1 1.5e-16 60.2 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 AJZ75651.1 - 8.4e-33 113.7 0.0 1.1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AJZ75651.1 - 2.7e-12 46.5 0.2 5.2e-12 45.6 0.2 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KH_1 PF00013.29 AJZ75652.1 - 6.5e-08 32.3 1.6 1.4e-07 31.2 1.3 1.7 2 0 0 2 2 2 1 KH domain KH_6 PF15985.5 AJZ75652.1 - 3.1e-05 24.2 0.0 5.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 AJZ75652.1 - 0.00034 20.4 0.4 0.00074 19.3 0.4 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 AJZ75652.1 - 0.012 15.5 0.1 0.051 13.4 0.1 2.0 1 1 1 2 2 2 0 KH domain SBDS PF01172.18 AJZ75653.1 - 1.2e-22 79.8 0.1 1.2e-22 79.8 0.1 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 AJZ75653.1 - 1.5e-19 70.1 0.2 3.3e-19 69.0 0.1 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain EFG_C PF00679.24 AJZ75653.1 - 0.0018 18.2 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus DUF5632 PF18646.1 AJZ75653.1 - 0.16 12.0 0.0 0.46 10.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5632) RNA_pol_A_bac PF01000.26 AJZ75654.1 - 1.3e-25 90.0 0.0 2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 AJZ75654.1 - 2e-14 52.7 0.0 2.5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L13 PF00572.18 AJZ75655.1 - 1.3e-08 35.2 0.0 2.1e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L13 Pox_L5 PF04872.13 AJZ75655.1 - 0.063 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus L5 protein family Ribosomal_S9 PF00380.19 AJZ75656.1 - 4.4e-33 114.4 1.1 5e-33 114.2 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 NTP_transferase PF00483.23 AJZ75657.1 - 1.4e-20 74.0 0.0 1.6e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AJZ75657.1 - 1.6e-11 44.8 0.0 1.9e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AJZ75657.1 - 4.6e-05 23.3 0.0 6.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 AJZ75657.1 - 0.003 17.5 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase Antimicrobial_7 PF08102.11 AJZ75657.1 - 0.024 14.9 0.2 0.26 11.5 0.2 2.5 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Aconitase_C PF00694.19 AJZ75658.1 - 8e-37 126.5 0.0 1.1e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 AJZ75658.1 - 0.0028 17.3 0.0 0.042 13.5 0.0 2.0 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase PF00330.20 AJZ75659.1 - 4.9e-151 503.8 0.0 5.5e-151 503.7 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 AJZ75659.1 - 0.0004 19.2 0.0 0.00077 18.3 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF521) Aconitase_C PF00694.19 AJZ75660.1 - 4.8e-21 75.5 0.0 2.3e-20 73.3 0.0 2.0 1 1 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 AJZ75660.1 - 0.00025 20.7 0.2 0.0013 18.4 0.2 1.9 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus P22_CoatProtein PF11651.8 AJZ75660.1 - 0.024 13.3 0.0 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 F420_ligase PF01996.16 AJZ75661.1 - 2.1e-45 155.0 0.6 3.3e-45 154.4 0.1 1.5 2 0 0 2 2 2 1 F420-0:Gamma-glutamyl ligase Nsp1_C PF05064.13 AJZ75664.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region TPP_enzyme_C PF02775.21 AJZ75665.1 - 6.8e-31 107.1 0.3 1.2e-30 106.3 0.3 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 AJZ75665.1 - 3.3e-16 59.2 0.4 2.6e-14 53.1 0.4 2.4 1 1 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal POR_N PF01855.19 AJZ75666.1 - 2.5e-56 191.0 0.0 3.6e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 AJZ75666.1 - 2.3e-35 122.3 0.1 4.9e-35 121.2 0.1 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 AJZ75666.1 - 1.7e-12 47.5 0.0 3.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 AJZ75666.1 - 1.9e-06 27.8 0.0 4.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_N PF02776.18 AJZ75666.1 - 0.009 15.6 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2-Hacid_dh_C PF02826.19 AJZ75667.1 - 1.3e-64 216.8 0.1 2e-64 216.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AJZ75667.1 - 4.3e-31 107.3 0.0 4.9e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AJZ75667.1 - 2.8e-07 30.8 0.0 4.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 AJZ75667.1 - 4.4e-06 26.4 0.0 9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 AJZ75667.1 - 0.006 17.1 0.0 0.015 15.8 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 AJZ75667.1 - 0.023 14.8 0.1 0.3 11.1 0.0 2.4 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 AJZ75667.1 - 0.042 13.1 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Inos-1-P_synth PF01658.17 AJZ75668.1 - 6.8e-28 97.1 0.3 1.5e-27 96.0 0.0 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase AMP-binding_C_2 PF14535.6 AJZ75668.1 - 0.029 14.7 0.1 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain CBM_X2 PF03442.14 AJZ75669.1 - 0.056 13.6 0.7 0.12 12.5 0.3 1.8 2 0 0 2 2 2 0 Carbohydrate binding domain X2 LTD PF00932.19 AJZ75669.1 - 0.06 13.7 0.2 0.099 13.0 0.2 1.5 1 1 0 1 1 1 0 Lamin Tail Domain GLF PF03275.13 AJZ75669.1 - 0.081 12.6 0.2 0.09 12.5 0.2 1.1 1 0 0 1 1 1 0 UDP-galactopyranose mutase TruB_N PF01509.18 AJZ75670.1 - 2.4e-24 86.4 1.9 2.5e-14 53.9 0.0 3.5 2 1 1 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AJZ75670.1 - 1.6e-20 73.0 0.0 5.7e-20 71.2 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 AJZ75670.1 - 6.4e-17 61.3 0.1 1.3e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 PUA domain DKCLD PF08068.12 AJZ75670.1 - 1.1e-09 38.2 0.0 2.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 DKCLD (NUC011) domain AAA_18 PF13238.6 AJZ75671.1 - 1.8e-10 41.5 0.0 2.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AJZ75671.1 - 6.2e-10 39.5 0.0 1.9e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_17 PF13207.6 AJZ75671.1 - 3.6e-07 30.7 0.2 7.1e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 AJZ75671.1 - 5e-05 23.1 0.2 0.0022 17.8 0.1 2.1 1 1 1 2 2 2 1 Cytidylate kinase ADK PF00406.22 AJZ75671.1 - 0.0002 21.5 2.1 0.0008 19.5 0.1 2.2 2 1 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.6 AJZ75671.1 - 0.00022 21.5 0.0 0.00038 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AJZ75671.1 - 0.0025 18.0 0.1 0.0055 16.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 AJZ75671.1 - 0.0073 16.7 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase SKI PF01202.22 AJZ75671.1 - 0.0095 16.1 0.8 0.052 13.7 0.8 2.0 1 1 0 1 1 1 1 Shikimate kinase AAA PF00004.29 AJZ75671.1 - 0.017 15.6 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 AJZ75671.1 - 0.08 12.4 0.1 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RuvB_N PF05496.12 AJZ75671.1 - 0.082 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 AJZ75671.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_26 PF13500.6 AJZ75671.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 AJZ75671.1 - 0.15 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain EMC3_TMCO1 PF01956.16 AJZ75672.1 - 7.3e-16 58.4 10.6 3e-15 56.4 10.6 1.8 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like AAA_17 PF13207.6 AJZ75673.1 - 2.3e-30 105.8 0.1 3e-30 105.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 AJZ75673.1 - 3.4e-07 30.1 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 AJZ75673.1 - 3.6e-06 26.8 0.6 5.9e-06 26.1 0.6 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AJZ75673.1 - 2.9e-05 24.6 0.1 6.6e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 AJZ75673.1 - 0.00012 22.0 0.1 0.00016 21.7 0.1 1.4 1 1 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 AJZ75673.1 - 0.00017 21.9 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AJZ75673.1 - 0.00019 21.4 1.5 0.00019 21.4 1.5 2.3 2 1 1 3 3 3 1 NTPase MobB PF03205.14 AJZ75673.1 - 0.00048 20.0 1.4 0.00076 19.4 0.8 1.6 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.10 AJZ75673.1 - 0.00056 19.4 0.3 0.001 18.6 0.1 1.5 2 0 0 2 2 1 1 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 AJZ75673.1 - 0.00065 19.6 1.3 0.0011 18.8 0.2 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 AJZ75673.1 - 0.00083 19.9 0.5 0.00094 19.7 0.5 1.4 1 1 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 AJZ75673.1 - 0.0014 18.6 1.0 0.0016 18.4 0.3 1.4 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea cobW PF02492.19 AJZ75673.1 - 0.002 17.7 0.1 0.0031 17.1 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 AJZ75673.1 - 0.0032 17.0 0.1 0.0052 16.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 AJZ75673.1 - 0.0034 17.4 1.1 0.0076 16.3 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AJZ75673.1 - 0.0036 17.6 1.4 0.0067 16.8 1.3 1.8 1 1 1 2 2 1 1 AAA domain Roc PF08477.13 AJZ75673.1 - 0.0054 16.9 0.3 0.011 16.0 0.3 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 AJZ75673.1 - 0.0057 16.4 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 AJZ75673.1 - 0.0061 15.8 0.1 0.0089 15.2 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 AJZ75673.1 - 0.008 16.3 0.1 0.016 15.4 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 AJZ75673.1 - 0.0087 16.3 0.4 0.016 15.5 0.4 1.7 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 AJZ75673.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE APS_kinase PF01583.20 AJZ75673.1 - 0.011 15.6 0.2 0.022 14.7 0.1 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase HU-CCDC81_euk_1 PF14908.6 AJZ75673.1 - 0.013 15.6 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 AAA PF00004.29 AJZ75673.1 - 0.013 15.9 1.8 0.033 14.6 1.8 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 AJZ75673.1 - 0.013 15.1 1.3 0.059 13.0 0.6 2.4 2 1 0 2 2 2 0 Thymidylate kinase SRPRB PF09439.10 AJZ75673.1 - 0.014 14.8 0.1 0.021 14.3 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 AJZ75673.1 - 0.015 15.3 0.2 0.022 14.9 0.2 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF4411 PF14367.6 AJZ75673.1 - 0.019 14.9 1.2 0.19 11.6 0.0 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4411) ResIII PF04851.15 AJZ75673.1 - 0.021 14.8 1.2 0.031 14.3 1.2 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit MeaB PF03308.16 AJZ75673.1 - 0.025 13.5 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 AJZ75673.1 - 0.027 14.4 0.6 0.059 13.3 0.6 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 AJZ75673.1 - 0.027 14.8 0.2 0.049 14.0 0.2 1.4 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 AJZ75673.1 - 0.032 14.0 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PIF1 PF05970.14 AJZ75673.1 - 0.033 13.3 0.2 0.052 12.7 0.2 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_24 PF13479.6 AJZ75673.1 - 0.038 13.7 0.9 0.047 13.4 0.9 1.5 1 1 0 1 1 1 0 AAA domain DUF463 PF04317.12 AJZ75673.1 - 0.039 12.9 0.1 0.052 12.5 0.1 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 DUF2075 PF09848.9 AJZ75673.1 - 0.044 13.0 0.1 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.9 AJZ75673.1 - 0.053 13.3 0.5 0.096 12.4 0.4 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.23 AJZ75673.1 - 0.065 13.3 0.1 0.095 12.8 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 AJZ75673.1 - 0.068 12.4 0.3 0.15 11.3 0.3 1.6 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 AJZ75673.1 - 0.069 12.5 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arf PF00025.21 AJZ75673.1 - 0.08 12.4 1.5 0.094 12.2 0.3 1.8 2 1 0 2 2 1 0 ADP-ribosylation factor family TrwB_AAD_bind PF10412.9 AJZ75673.1 - 0.095 11.6 0.2 0.14 11.0 0.2 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 AJZ75673.1 - 0.099 12.6 0.3 0.28 11.2 0.1 1.7 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF1499 PF07386.11 AJZ75673.1 - 0.1 13.2 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) DnaB_C PF03796.15 AJZ75673.1 - 0.13 11.6 1.1 0.17 11.2 0.3 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DUF87 PF01935.17 AJZ75673.1 - 0.18 11.9 1.7 0.43 10.6 1.7 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain SecY PF00344.20 AJZ75674.1 - 3.2e-62 210.5 16.9 4.1e-62 210.2 16.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 AJZ75674.1 - 1.3e-10 40.9 1.3 6e-10 38.8 1.3 2.3 1 0 0 1 1 1 1 Plug domain of Sec61p Phage_holin_5_1 PF06946.11 AJZ75674.1 - 0.084 13.3 0.1 0.084 13.3 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 Ribosomal_L27A PF00828.19 AJZ75675.1 - 1.4e-14 54.9 1.8 2.4e-14 54.1 1.8 1.5 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 AJZ75675.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L30 PF00327.20 AJZ75676.1 - 1.2e-10 41.1 0.1 2.8e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5 PF00333.20 AJZ75677.1 - 4.1e-23 81.1 0.7 8.9e-23 80.1 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 AJZ75677.1 - 8e-16 57.3 0.8 1.1e-15 56.8 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_L5e PF17144.4 AJZ75678.1 - 9.1e-18 64.8 1.5 4e-14 52.9 0.5 2.7 1 1 1 2 2 2 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18p PF00861.22 AJZ75678.1 - 0.00043 20.6 0.2 0.00058 20.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast SRP54 PF00448.22 AJZ75679.1 - 3.4e-71 238.9 1.4 5.1e-71 238.4 1.4 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 AJZ75679.1 - 1.7e-09 37.7 5.3 1.7e-09 37.7 5.3 2.0 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 AJZ75679.1 - 4.9e-07 29.7 0.1 8.2e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain Trypan_PARP PF05887.11 AJZ75679.1 - 4.2e-06 26.8 34.8 4.2e-06 26.8 34.8 2.4 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Zeta_toxin PF06414.12 AJZ75679.1 - 1.7e-05 24.2 0.1 2.6e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.23 AJZ75679.1 - 0.00013 22.0 0.2 0.0003 20.9 0.2 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 AJZ75679.1 - 0.00013 21.6 0.8 0.00029 20.5 0.8 1.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 AJZ75679.1 - 0.00026 20.4 0.1 0.00038 19.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 AJZ75679.1 - 0.00047 19.4 0.2 0.00073 18.8 0.2 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_17 PF13207.6 AJZ75679.1 - 0.00068 20.1 0.0 0.00068 20.1 0.0 2.1 3 0 0 3 3 2 1 AAA domain APS_kinase PF01583.20 AJZ75679.1 - 0.00079 19.4 0.2 0.0083 16.0 0.0 2.2 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_22 PF13401.6 AJZ75679.1 - 0.001 19.4 0.1 0.0028 17.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AJZ75679.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 AJZ75679.1 - 0.0018 18.6 0.3 0.003 17.9 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AJZ75679.1 - 0.0026 18.2 0.1 0.0063 16.9 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AJZ75679.1 - 0.0027 17.9 0.0 0.0047 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AJZ75679.1 - 0.0028 17.7 1.4 0.0056 16.7 0.2 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 AJZ75679.1 - 0.0031 17.2 0.1 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase TPP_enzyme_M PF00205.22 AJZ75679.1 - 0.0032 17.2 0.6 0.1 12.4 0.2 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain ABC_tran PF00005.27 AJZ75679.1 - 0.0047 17.4 0.0 0.0087 16.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_15 PF13175.6 AJZ75679.1 - 0.0049 16.6 0.3 0.0049 16.6 0.3 2.7 1 1 1 2 2 2 1 AAA ATPase domain ResIII PF04851.15 AJZ75679.1 - 0.0064 16.5 2.8 0.033 14.2 2.8 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 AJZ75679.1 - 0.0081 15.9 0.3 0.022 14.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 AJZ75679.1 - 0.0096 16.2 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 AJZ75679.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit MobB PF03205.14 AJZ75679.1 - 0.02 14.8 0.7 0.057 13.3 0.3 1.9 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KdpD PF02702.17 AJZ75679.1 - 0.02 14.4 0.1 0.039 13.4 0.1 1.5 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain AAA_7 PF12775.7 AJZ75679.1 - 0.034 13.6 0.1 0.089 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 AJZ75679.1 - 0.051 13.6 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 AJZ75679.1 - 0.053 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 AJZ75679.1 - 0.054 13.5 0.1 0.13 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AJZ75679.1 - 0.055 13.4 1.0 1.9 8.4 1.0 2.4 1 1 0 1 1 1 0 NTPase 6PF2K PF01591.18 AJZ75679.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase KTI12 PF08433.10 AJZ75679.1 - 0.066 12.6 0.0 0.19 11.1 0.0 1.8 1 1 0 1 1 1 0 Chromatin associated protein KTI12 T2SSE PF00437.20 AJZ75679.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TK PF00265.18 AJZ75679.1 - 0.13 12.2 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Thymidine kinase CLP1_P PF16575.5 AJZ75679.1 - 0.15 11.9 0.4 0.66 9.7 0.0 2.0 1 1 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Helicase_RecD PF05127.14 AJZ75679.1 - 0.15 11.9 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Helicase SPOUT_MTase PF02590.17 AJZ75679.1 - 0.33 10.9 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 1 0 Predicted SPOUT methyltransferase DUF3408 PF11888.8 AJZ75679.1 - 1.4 9.0 13.1 0.55 10.4 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Cupin_2 PF07883.11 AJZ75680.1 - 7.3e-08 32.0 0.0 1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AJZ75680.1 - 1.4e-06 28.3 0.0 1.8e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 AJZ75680.1 - 0.059 13.3 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Cupin_1 PF00190.22 AJZ75680.1 - 0.098 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Cupin Sod_Fe_C PF02777.18 AJZ75681.1 - 6.2e-39 132.3 0.3 9.8e-39 131.7 0.3 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AJZ75681.1 - 1e-27 96.4 0.9 2.2e-27 95.3 0.9 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Peptidase_S8 PF00082.22 AJZ75682.1 - 4.1e-56 190.4 0.2 7.4e-56 189.6 0.2 1.4 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 AJZ75682.1 - 6.4e-14 51.8 0.1 2.3e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 PA domain DUF2388 PF09498.10 AJZ75682.1 - 0.086 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) Ribosomal_L32e PF01655.18 AJZ75683.1 - 3.9e-36 123.8 0.5 4.6e-36 123.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L19e PF01280.20 AJZ75684.1 - 1.8e-40 138.3 8.7 2.1e-40 138.1 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e DNA_binding_1 PF01035.20 AJZ75685.1 - 1.1e-27 95.9 0.0 1.3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain tRNA_deacylase PF04414.12 AJZ75686.1 - 7.5e-59 198.7 0.1 9.4e-59 198.4 0.1 1.1 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase MbeD_MobD PF04899.12 AJZ75686.1 - 0.03 14.4 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 MbeD/MobD like SecE PF00584.20 AJZ75687.1 - 0.0001 22.1 0.1 0.00011 22.0 0.1 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Ribosomal_L11_N PF03946.14 AJZ75688.1 - 6.5e-22 77.1 1.2 6.5e-22 77.1 1.2 1.9 2 1 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AJZ75688.1 - 1.7e-18 66.9 1.7 3e-18 66.1 1.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Peptidase_M23_N PF18421.1 AJZ75688.1 - 0.024 14.5 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain Ribosomal_L1 PF00687.21 AJZ75689.1 - 8.7e-42 143.2 0.4 9.8e-42 143.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RL10P_insert PF17777.1 AJZ75690.1 - 1.4e-18 66.7 0.1 3.4e-18 65.4 0.1 1.7 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 AJZ75690.1 - 7.2e-18 64.6 0.8 1.5e-17 63.5 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 NepR PF18557.1 AJZ75690.1 - 0.31 10.7 1.2 0.54 9.9 0.2 1.8 2 0 0 2 2 2 0 Anti-sigma factor NepR Ribosomal_60s PF00428.19 AJZ75691.1 - 1.3e-13 51.3 18.0 1.5e-13 51.1 18.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Adeno_PV PF03910.13 AJZ75691.1 - 1.1 7.9 4.3 1.3 7.6 4.3 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV tRNA-synt_2c PF01411.19 AJZ75693.1 - 1.3e-82 278.1 0.0 2.8e-82 277.0 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 AJZ75693.1 - 8.8e-16 57.7 0.9 2.5e-15 56.3 0.9 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 AJZ75693.1 - 5e-09 36.7 0.8 1.2e-08 35.4 0.8 1.6 1 0 0 1 1 1 1 DHHA1 domain tRNA-synt_1 PF00133.22 AJZ75694.1 - 6.2e-54 183.3 1.4 2.4e-52 178.0 1.4 2.7 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AJZ75694.1 - 6e-24 84.5 0.1 3.6e-12 45.7 0.0 3.3 2 1 1 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 AJZ75694.1 - 1.5e-22 80.2 0.1 3.4e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 AJZ75694.1 - 2.1e-12 47.0 0.0 1.4e-06 27.9 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 AJZ75694.1 - 8.3e-09 35.2 0.3 4.7e-07 29.5 0.3 2.8 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 STI1 PF17830.1 AJZ75694.1 - 0.0019 18.1 0.1 0.049 13.6 0.1 2.8 2 0 0 2 2 2 1 STI1 domain SAM_1 PF00536.30 AJZ75694.1 - 0.048 14.1 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Trp_halogenase PF04820.14 AJZ75695.1 - 0.00013 21.0 0.0 0.00038 19.4 0.0 1.6 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_2 PF03446.15 AJZ75695.1 - 0.026 14.7 0.0 0.064 13.4 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Na_H_Exchanger PF00999.21 AJZ75696.1 - 2.4e-58 197.8 58.8 3e-58 197.4 58.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CxxCxxCC PF03692.15 AJZ75697.1 - 2.1e-09 37.9 0.1 4.8e-09 36.8 0.1 1.6 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain DUF2405 PF10293.9 AJZ75698.1 - 0.1 12.5 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) Ribosomal_S7 PF00177.21 AJZ75699.1 - 2.5e-37 127.8 1.8 4e-37 127.1 1.8 1.3 1 1 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.25 AJZ75700.1 - 1.3e-47 160.1 0.2 1.8e-47 159.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 KH_2 PF07650.17 AJZ75701.1 - 4.9e-20 71.1 3.8 8.8e-14 51.1 0.2 2.1 1 1 1 2 2 2 2 KH domain KH_5 PF13184.6 AJZ75701.1 - 4.9e-10 39.4 4.1 8.9e-10 38.5 0.4 2.1 2 0 0 2 2 2 1 NusA-like KH domain KH_4 PF13083.6 AJZ75701.1 - 9.3e-10 38.3 1.2 0.00055 19.8 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_1 PF00013.29 AJZ75701.1 - 2.3e-05 24.1 0.3 0.0057 16.4 0.1 2.4 2 0 0 2 2 2 2 KH domain Ribosomal_L7Ae PF01248.26 AJZ75702.1 - 3.5e-11 42.7 2.0 4e-11 42.5 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Kazal_1 PF00050.21 AJZ75703.1 - 8.3e-08 32.1 2.3 1.4e-07 31.4 1.3 1.9 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 AJZ75703.1 - 1.6e-05 24.9 0.2 3.8e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain PD40 PF07676.12 AJZ75703.1 - 0.005 16.7 0.7 4 7.5 0.1 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat RNR_inhib PF08591.10 AJZ75703.1 - 0.14 13.5 0.9 0.22 12.8 0.1 1.7 2 0 0 2 2 2 0 Ribonucleotide reductase inhibitor Wzt_C PF14524.6 AJZ75704.1 - 0.019 15.0 0.2 0.044 13.8 0.2 1.6 1 0 0 1 1 1 0 Wzt C-terminal domain HCBP_related PF06594.11 AJZ75704.1 - 0.13 12.2 1.7 0.4 10.6 0.1 2.8 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain Gmad2 PF10648.9 AJZ75704.1 - 0.17 12.2 2.1 2.8 8.3 0.5 2.9 3 0 0 3 3 3 0 Immunoglobulin-like domain of bacterial spore germination RNA_pol_Rpb1_1 PF04997.12 AJZ75705.1 - 2.9e-94 315.9 0.0 7.9e-94 314.5 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 AJZ75705.1 - 8.5e-83 277.8 3.8 2.1e-82 276.6 2.5 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 AJZ75705.1 - 6.8e-72 241.1 0.0 1.2e-71 240.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AJZ75705.1 - 2e-32 112.3 0.0 4.6e-32 111.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AJZ75705.1 - 1.9e-26 92.1 0.3 5.6e-26 90.6 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb2_6 PF00562.28 AJZ75706.1 - 2.2e-124 415.5 0.0 3.9e-124 414.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 AJZ75706.1 - 9.6e-49 165.6 0.0 1.8e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 AJZ75706.1 - 5e-33 113.4 0.2 1.1e-32 112.3 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 AJZ75706.1 - 7.6e-29 99.7 0.0 1.7e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 AJZ75706.1 - 4.1e-23 82.0 0.0 8.4e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 AJZ75706.1 - 1e-17 64.2 0.2 2.5e-17 62.9 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 AJZ75706.1 - 4e-08 33.7 0.0 1.5e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 FYVE_2 PF02318.16 AJZ75706.1 - 0.034 14.4 0.1 0.061 13.5 0.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 AJZ75706.1 - 0.23 11.6 0.3 0.44 10.7 0.3 1.4 1 0 0 1 1 1 0 FYVE zinc finger OrfB_Zn_ribbon PF07282.11 AJZ75706.1 - 0.23 11.4 2.5 0.43 10.5 1.1 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_L37e PF01907.19 AJZ75706.1 - 0.46 10.7 1.2 1 9.6 1.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L37e zf-CCHC_2 PF13696.6 AJZ75706.1 - 5.6 6.9 5.5 6 6.8 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle Aminotran_5 PF00266.19 AJZ75707.1 - 9.9e-85 284.7 1.0 1.2e-84 284.5 1.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AJZ75707.1 - 1.6e-10 40.7 0.1 3e-10 39.8 0.1 1.5 1 1 1 2 2 2 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AJZ75707.1 - 0.0003 20.2 0.1 0.0018 17.7 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 AJZ75707.1 - 0.036 12.8 0.0 0.061 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain QueC PF06508.13 AJZ75708.1 - 4.5e-09 36.1 0.0 2.6e-08 33.6 0.1 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AJZ75708.1 - 6.1e-09 36.0 0.0 9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.16 AJZ75708.1 - 7.7e-09 34.8 0.2 8.9e-07 28.0 0.1 2.2 2 0 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 AJZ75708.1 - 1.8e-08 33.8 0.0 2.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 AJZ75708.1 - 5e-07 29.6 0.1 2.9e-06 27.2 0.2 2.0 2 0 0 2 2 2 1 PP-loop family HET-s_218-289 PF11558.8 AJZ75708.1 - 0.057 13.4 0.2 0.17 11.9 0.2 1.7 1 1 0 1 1 1 0 Het-s 218-289 Ldh_1_N PF00056.23 AJZ75709.1 - 5.7e-36 123.7 1.1 1e-35 122.9 1.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AJZ75709.1 - 6.5e-24 84.7 0.1 9.7e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4C PF11975.8 AJZ75709.1 - 0.17 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain AIRC PF00731.20 AJZ75710.1 - 1e-17 64.1 3.1 1.7e-17 63.4 3.1 1.4 1 0 0 1 1 1 1 AIR carboxylase Rtt106 PF08512.12 AJZ75710.1 - 0.11 12.9 0.4 0.2 12.1 0.4 1.5 1 1 0 1 1 1 0 Histone chaperone Rttp106-like AF0941-like PF14591.6 AJZ75710.1 - 0.72 10.4 4.2 0.65 10.6 1.4 2.1 1 1 1 2 2 2 0 AF0941-like VIT1 PF01988.19 AJZ75711.1 - 2.6e-51 174.5 1.0 3e-51 174.4 1.0 1.0 1 0 0 1 1 1 1 VIT family Radical_SAM PF04055.21 AJZ75712.1 - 7.6e-13 49.2 0.0 1.4e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 AJZ75712.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 B12 binding domain TerY_C PF15616.6 AJZ75713.1 - 0.04 14.0 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain HigB_toxin PF09907.9 AJZ75713.1 - 0.14 12.4 0.6 0.46 10.7 0.1 2.0 3 0 0 3 3 3 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system Zip PF02535.22 AJZ75714.1 - 2.9e-06 26.7 17.5 2.9e-06 26.7 17.5 2.2 1 1 0 2 2 2 1 ZIP Zinc transporter DUF4342 PF14242.6 AJZ75714.1 - 0.31 11.0 0.1 0.31 11.0 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4342) DUF2374 PF09574.10 AJZ75715.1 - 0.042 13.7 1.3 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) HCV_NS4a PF01006.20 AJZ75715.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a TrmB PF01978.19 AJZ75716.1 - 0.0042 16.9 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DNA_processg_A PF02481.15 AJZ75716.1 - 0.005 16.1 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 DNA recombination-mediator protein A DUF4423 PF14394.6 AJZ75716.1 - 0.03 14.0 0.0 0.041 13.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_5 PF01022.20 AJZ75716.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family VWA_2 PF13519.6 AJZ75717.1 - 1.3e-09 38.7 0.1 7.9e-09 36.1 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain AAA_5 PF07728.14 AJZ75718.1 - 2.3e-08 34.2 0.0 0.00019 21.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 AJZ75718.1 - 1.5e-07 30.7 0.0 7.2e-07 28.4 0.0 1.9 1 1 0 1 1 1 1 PrkA AAA domain AAA_3 PF07726.11 AJZ75718.1 - 6.6e-06 26.0 0.0 0.00012 21.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AJZ75718.1 - 1.1e-05 25.2 0.0 4.9e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 AJZ75718.1 - 0.0004 19.6 0.0 0.0054 15.8 0.0 2.1 2 0 0 2 2 2 1 MCM P-loop domain Mg_chelatase PF01078.21 AJZ75718.1 - 0.012 15.0 0.0 1.3 8.4 0.0 2.6 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI Ribosomal_S13 PF00416.22 AJZ75719.1 - 5.3e-40 136.8 0.0 6.2e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 S4 PF01479.25 AJZ75720.1 - 6.3e-10 38.6 0.0 6.3e-10 38.6 0.0 2.1 3 0 0 3 3 3 1 S4 domain SIS PF01380.22 AJZ75721.1 - 1.4e-46 157.5 1.3 2.5e-23 82.4 1.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 AJZ75721.1 - 9.4e-22 77.6 0.0 1.7e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AJZ75721.1 - 5.1e-16 58.7 0.0 1.5e-15 57.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain SIS_2 PF13580.6 AJZ75721.1 - 1.1e-05 25.5 2.5 0.0042 17.1 0.3 3.2 2 1 1 3 3 3 2 SIS domain GATase_4 PF13230.6 AJZ75721.1 - 0.0013 17.7 0.1 0.002 17.1 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DBI_PRT PF02277.17 AJZ75722.1 - 1.8e-12 47.2 0.6 2.5e-12 46.7 0.6 1.2 1 0 0 1 1 1 1 Phosphoribosyltransferase Lactamase_B PF00753.27 AJZ75723.1 - 6.6e-20 72.0 2.0 3.4e-11 43.5 0.1 2.1 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AJZ75723.1 - 1.2e-06 28.2 0.1 2.1e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CBS PF00571.28 AJZ75723.1 - 0.11 13.0 0.0 0.56 10.7 0.0 2.1 2 0 0 2 2 2 0 CBS domain YjeF_N PF03853.15 AJZ75724.1 - 2.4e-47 161.0 0.1 2.8e-47 160.8 0.1 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus Translin PF01997.16 AJZ75725.1 - 1.2e-06 28.6 7.7 1.4e-05 25.2 5.1 2.4 2 1 0 2 2 2 1 Translin family BAR_3 PF16746.5 AJZ75725.1 - 0.12 12.0 5.5 0.056 13.1 3.3 1.5 2 0 0 2 2 2 0 BAR domain of APPL family Polo_box_2 PF18531.1 AJZ75725.1 - 0.13 12.4 1.2 0.18 11.9 0.1 1.7 2 0 0 2 2 2 0 Polo box domain Snf7 PF03357.21 AJZ75725.1 - 0.13 11.8 7.1 0.34 10.5 7.1 1.6 1 0 0 1 1 1 0 Snf7 JHD PF17811.1 AJZ75725.1 - 1.2 9.7 6.4 29 5.3 0.0 2.2 2 0 0 2 2 2 0 Jumonji helical domain Enolase_C PF00113.22 AJZ75726.1 - 1.3e-57 195.3 0.1 2e-57 194.7 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 AJZ75726.1 - 2.2e-23 82.9 0.2 4e-23 82.0 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 AJZ75726.1 - 8.7e-05 22.2 0.0 0.0003 20.4 0.0 1.8 1 1 1 2 2 2 1 Enolase C-terminal domain-like CP_ATPgrasp_2 PF14403.6 AJZ75726.1 - 0.0037 16.3 0.0 0.0054 15.7 0.0 1.1 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 AJZ75726.1 - 0.0065 15.5 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 A circularly permuted ATPgrasp MAAL_N PF05034.13 AJZ75726.1 - 0.0081 15.8 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase N-terminus DBP10CT PF08147.12 AJZ75726.1 - 0.009 16.2 1.6 0.046 14.0 0.1 2.4 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Pinin_SDK_N PF04697.13 AJZ75726.1 - 0.047 14.3 0.0 0.098 13.3 0.0 1.5 1 0 0 1 1 1 0 pinin/SDK conserved region Ribosomal_S2 PF00318.20 AJZ75727.1 - 1.5e-23 83.1 0.2 4.5e-12 45.7 0.4 2.0 2 0 0 2 2 2 2 Ribosomal protein S2 Phage_lysozyme PF00959.19 AJZ75727.1 - 0.079 13.4 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Phage lysozyme Memo PF01875.17 AJZ75728.1 - 2.6e-78 262.9 0.2 3e-78 262.7 0.2 1.0 1 0 0 1 1 1 1 Memo-like protein GHMP_kinases_N PF00288.26 AJZ75729.1 - 1.2e-14 54.3 1.1 2.8e-14 53.1 1.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AJZ75729.1 - 1.3e-11 44.7 0.1 2.8e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 AJZ75729.1 - 0.0029 17.1 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature AA_kinase PF00696.28 AJZ75730.1 - 2.4e-30 105.9 0.0 2.8e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family NUDIX PF00293.28 AJZ75731.1 - 1.1e-15 57.9 0.1 2.9e-15 56.5 0.0 1.7 1 1 1 2 2 2 1 NUDIX domain polyprenyl_synt PF00348.17 AJZ75732.1 - 1.6e-69 233.8 0.0 1.9e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase tRNA-synt_1c PF00749.21 AJZ75733.1 - 3.3e-79 266.1 0.0 4.2e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 AJZ75733.1 - 1.7e-24 86.6 0.0 3.9e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DEK_C PF08766.11 AJZ75733.1 - 0.033 14.1 0.1 0.088 12.7 0.1 1.8 1 0 0 1 1 1 0 DEK C terminal domain tRNA-synt_1e PF01406.19 AJZ75733.1 - 0.13 11.6 1.8 1.5 8.0 1.8 2.2 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain FAA_hydrolase PF01557.18 AJZ75734.1 - 3.1e-68 229.7 0.0 3.8e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 AJZ75734.1 - 0.0036 18.2 0.0 0.03 15.2 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF2437) Rieske PF00355.26 AJZ75735.1 - 2.6e-19 69.0 0.0 3e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AJZ75735.1 - 1.4e-06 28.1 0.0 1.7e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0147 PF03685.13 AJZ75736.1 - 5.9e-29 100.0 0.5 6.7e-29 99.8 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) UPF0253 PF06786.12 AJZ75736.1 - 0.001 19.3 0.2 0.15 12.4 0.1 2.2 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0253) DUF1539 PF07560.11 AJZ75736.1 - 0.032 14.3 0.3 0.05 13.7 0.3 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) TMP_2 PF06791.13 AJZ75736.1 - 0.034 13.8 0.4 0.041 13.6 0.4 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein DOT1 PF08123.13 AJZ75737.1 - 1.4e-06 28.0 0.1 0.0013 18.3 0.0 2.1 1 1 1 2 2 2 2 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 AJZ75737.1 - 0.00011 22.8 0.0 0.00026 21.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJZ75737.1 - 0.00017 22.3 0.0 0.00032 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJZ75737.1 - 0.00017 21.4 0.2 0.00035 20.4 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AJZ75737.1 - 0.02 14.2 0.0 0.039 13.2 0.0 1.4 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 AJZ75737.1 - 0.062 14.1 0.0 0.099 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 AJZ75737.1 - 0.099 12.5 0.0 0.16 11.8 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain GspL_C PF12693.7 AJZ75738.1 - 0.021 14.7 0.1 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 GspL periplasmic domain CorA PF01544.18 AJZ75739.1 - 2.2e-58 197.9 3.2 2.8e-58 197.6 3.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Cbl_N PF02262.16 AJZ75739.1 - 0.02 14.9 0.4 0.2 11.7 0.3 2.2 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 GCIP PF13324.6 AJZ75739.1 - 0.57 9.7 2.9 1.2 8.7 2.9 1.5 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting Radical_SAM PF04055.21 AJZ75740.1 - 6.5e-19 68.9 0.0 1.1e-18 68.2 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 AJZ75740.1 - 1.1e-18 67.4 0.0 2.7e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Fer4_14 PF13394.6 AJZ75740.1 - 0.072 13.2 0.2 0.98 9.6 0.2 2.7 1 1 0 1 1 1 0 4Fe-4S single cluster domain Ham1p_like PF01725.16 AJZ75741.1 - 3.1e-40 138.1 0.0 3.4e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RIO1 PF01163.22 AJZ75742.1 - 1.6e-09 37.7 0.0 2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 AJZ75742.1 - 6e-07 29.1 0.2 8.2e-07 28.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 AJZ75742.1 - 7e-05 22.3 0.0 0.00041 19.8 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AJZ75742.1 - 0.00017 21.6 0.0 0.00027 20.9 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.11 AJZ75742.1 - 0.001 18.7 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.17 AJZ75742.1 - 0.0016 17.8 0.1 0.0022 17.3 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_14 PF17959.1 AJZ75742.1 - 0.11 12.8 0.0 0.82 10.1 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain bPH_3 PF14470.6 AJZ75743.1 - 0.053 13.9 0.3 0.086 13.2 0.3 1.5 1 1 0 1 1 1 0 Bacterial PH domain Peptidase_M22 PF00814.25 AJZ75744.1 - 3.2e-72 243.5 0.0 3.7e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family MMR_HSR1_C PF08438.10 AJZ75745.1 - 4.7e-31 107.7 0.5 8.6e-31 106.8 0.5 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 AJZ75745.1 - 3.2e-21 75.5 0.1 2.1e-20 72.9 0.0 2.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase TGS PF02824.21 AJZ75745.1 - 4e-13 49.2 0.1 1e-12 47.9 0.1 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 AJZ75745.1 - 2.1e-07 30.6 1.9 5.2e-07 29.3 0.2 2.3 3 0 0 3 3 3 1 Ferrous iron transport protein B YchF-GTPase_C PF06071.13 AJZ75745.1 - 0.00072 19.7 0.5 0.0089 16.2 0.5 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1_Xtn PF16897.5 AJZ75745.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 AJZ75746.1 - 2.9e-11 44.0 0.0 3.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AJZ75746.1 - 1e-06 29.0 0.0 0.002 18.3 0.0 2.2 1 1 1 2 2 2 2 Cytidylate kinase-like family KTI12 PF08433.10 AJZ75746.1 - 0.00013 21.5 0.8 0.00028 20.4 0.2 1.7 1 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA PF00004.29 AJZ75746.1 - 0.00035 21.0 0.6 0.00084 19.8 0.6 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 AJZ75746.1 - 0.00052 20.4 1.5 0.00089 19.7 0.3 2.1 2 2 0 2 2 2 1 AAA domain CoaE PF01121.20 AJZ75746.1 - 0.00064 19.4 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Dephospho-CoA kinase NTPase_1 PF03266.15 AJZ75746.1 - 0.0017 18.3 1.0 0.0056 16.6 0.2 2.1 1 1 1 2 2 2 1 NTPase AAA_33 PF13671.6 AJZ75746.1 - 0.002 18.3 0.0 0.0041 17.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 AJZ75746.1 - 0.0026 17.9 0.0 0.0066 16.6 0.0 1.7 1 1 0 1 1 1 1 Shikimate kinase APS_kinase PF01583.20 AJZ75746.1 - 0.0039 17.1 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 Adenylylsulphate kinase Rad17 PF03215.15 AJZ75746.1 - 0.02 14.8 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 AJZ75746.1 - 0.021 14.5 0.0 0.093 12.4 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 AJZ75746.1 - 0.037 14.3 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 AJZ75746.1 - 0.042 13.7 0.2 0.11 12.3 0.1 1.7 1 1 1 2 2 2 0 Deoxynucleoside kinase AAA_5 PF07728.14 AJZ75746.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM_N PF14551.6 AJZ75746.1 - 0.084 13.5 0.5 4.4 7.9 0.4 2.5 1 1 0 1 1 1 0 MCM N-terminal domain CUT PF02376.15 AJZ75746.1 - 0.096 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 CUT domain TGT PF01702.18 AJZ75747.1 - 6e-66 223.0 0.0 8.1e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF5591 PF17884.1 AJZ75747.1 - 1.9e-09 37.5 0.1 3.6e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5591) Bcr-Abl_Oligo PF09036.10 AJZ75747.1 - 0.076 13.0 0.1 6.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Fer4 PF00037.27 AJZ75748.1 - 5.9e-11 41.7 10.8 7.8e-06 25.5 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJZ75748.1 - 3.8e-09 37.0 2.9 5.3e-09 36.5 2.9 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJZ75748.1 - 3.2e-08 33.6 1.4 4.8e-08 33.0 1.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AJZ75748.1 - 4.2e-08 32.9 8.9 0.00031 20.7 2.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AJZ75748.1 - 1.6e-06 28.6 4.5 0.0024 18.4 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_2 PF12797.7 AJZ75748.1 - 2.3e-06 27.3 8.5 0.0025 17.8 2.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AJZ75748.1 - 1.7e-05 24.9 4.6 8.4e-05 22.7 4.8 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJZ75748.1 - 4.1e-05 23.6 8.4 0.0013 18.8 9.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AJZ75748.1 - 7.3e-05 23.0 7.2 0.019 15.4 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AJZ75748.1 - 0.00026 21.8 3.8 0.3 12.0 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 AJZ75748.1 - 0.00082 20.2 2.2 0.46 11.4 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 AJZ75748.1 - 0.0018 18.9 10.1 0.0066 17.2 2.3 2.3 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_8 PF13183.6 AJZ75748.1 - 0.0021 18.5 5.8 0.02 15.3 6.0 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 AJZ75748.1 - 0.0028 18.5 10.2 0.087 13.8 3.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AJZ75748.1 - 0.011 16.3 6.7 0.36 11.4 6.7 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AJZ75748.1 - 0.73 10.0 9.6 1.7 8.9 2.5 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Beta-Casp PF10996.8 AJZ75750.1 - 9.4e-16 58.1 0.0 1.7e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 AJZ75750.1 - 5.4e-15 55.1 0.0 1.2e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 AJZ75750.1 - 4.4e-14 52.4 0.0 9.9e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 AJZ75750.1 - 9.6e-09 35.5 0.0 2.4e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AJZ75750.1 - 1.6e-08 34.3 0.0 3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AJZ75750.1 - 0.0001 22.2 0.0 0.00032 20.6 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1647 PF07801.11 AJZ75750.1 - 0.18 11.6 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) HhH-GPD PF00730.25 AJZ75751.1 - 1.9e-11 44.4 0.0 3.1e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein OGG_N PF07934.12 AJZ75751.1 - 1.8e-08 34.5 0.2 0.0031 17.6 0.0 2.5 1 1 1 2 2 2 2 8-oxoguanine DNA glycosylase, N-terminal domain HHH_2 PF12826.7 AJZ75751.1 - 0.0094 16.0 0.1 0.033 14.3 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF2483 PF10656.9 AJZ75751.1 - 0.037 14.2 0.2 0.072 13.3 0.2 1.4 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2483) HHH PF00633.23 AJZ75751.1 - 0.07 13.0 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF4974 PF16344.5 AJZ75751.1 - 1.8 8.6 5.6 3.3 7.8 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4974) Copper-bind PF00127.20 AJZ75752.1 - 2.3e-08 34.4 0.1 3.3e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJZ75752.1 - 0.0046 17.0 0.0 0.0066 16.6 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Lipase_C PF18067.1 AJZ75752.1 - 0.089 13.4 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipase C-terminal domain Cytochrome_B PF00033.19 AJZ75753.1 - 4.5e-28 98.4 11.4 4.5e-28 98.4 11.4 2.5 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 AJZ75753.1 - 8.8e-26 90.9 6.1 8.8e-26 90.9 6.1 3.0 3 1 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 AJZ75753.1 - 6e-10 39.3 1.8 6e-10 39.3 1.8 3.4 4 1 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD DUF4405 PF14358.6 AJZ75753.1 - 8.4e-05 23.0 4.7 8.4e-05 23.0 4.7 4.5 6 0 0 6 6 6 1 Domain of unknown function (DUF4405) UPF0542 PF15086.6 AJZ75753.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 XhlA PF10779.9 AJZ75753.1 - 1.6 9.0 3.6 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA OAD_gamma PF04277.13 AJZ75753.1 - 2.8 8.6 0.0 2.8 8.6 0.0 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Rieske PF00355.26 AJZ75754.1 - 1.8e-06 27.8 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain TAT_signal PF10518.9 AJZ75754.1 - 2.6e-05 23.9 0.3 2.6e-05 23.9 0.3 1.8 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 AJZ75754.1 - 0.017 14.4 0.1 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal MscS_porin PF12795.7 AJZ75755.1 - 0.0012 18.5 0.3 0.0018 17.9 0.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain EMP24_GP25L PF01105.24 AJZ75755.1 - 0.0025 17.8 0.1 0.005 16.8 0.0 1.5 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD CCDC144C PF14915.6 AJZ75755.1 - 0.0029 16.8 0.2 0.0039 16.4 0.2 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Big_1 PF02369.16 AJZ75755.1 - 0.0031 17.5 0.1 0.035 14.1 0.0 2.7 2 1 1 3 3 3 1 Bacterial Ig-like domain (group 1) Baculo_PEP_C PF04513.12 AJZ75755.1 - 0.0034 17.4 2.1 0.0068 16.5 2.1 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus SHE3 PF17078.5 AJZ75755.1 - 0.0037 17.0 0.2 0.0065 16.2 0.2 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 MG2 PF01835.19 AJZ75755.1 - 0.028 14.9 0.2 0.15 12.6 0.1 2.2 2 1 0 2 2 2 0 MG2 domain FlaC_arch PF05377.11 AJZ75755.1 - 0.028 14.8 1.0 0.22 11.9 1.0 2.3 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 AJZ75755.1 - 0.031 14.7 1.2 1.6 9.2 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 AJZ75755.1 - 0.042 14.1 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SpaA PF17802.1 AJZ75755.1 - 0.047 14.0 1.4 0.065 13.6 0.2 1.8 2 0 0 2 2 2 0 Prealbumin-like fold domain BLOC1_2 PF10046.9 AJZ75755.1 - 0.063 13.6 0.5 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFT57 PF10498.9 AJZ75755.1 - 0.071 12.1 0.2 0.11 11.5 0.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Filament PF00038.21 AJZ75755.1 - 0.072 12.7 0.1 0.099 12.2 0.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF948 PF06103.11 AJZ75755.1 - 0.091 13.0 0.3 0.29 11.4 0.3 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Mce4_CUP1 PF11887.8 AJZ75755.1 - 0.1 12.0 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative TPR_MLP1_2 PF07926.12 AJZ75755.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 AJZ75755.1 - 0.12 12.4 0.3 0.21 11.6 0.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 AJZ75755.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation Fusion_gly PF00523.18 AJZ75755.1 - 0.45 8.7 4.7 0.26 9.5 2.8 1.6 2 0 0 2 2 2 0 Fusion glycoprotein F0 ThiF PF00899.21 AJZ75757.1 - 2.5e-64 217.0 0.1 3.4e-64 216.5 0.1 1.1 1 0 0 1 1 1 1 ThiF family ThiS PF02597.20 AJZ75757.1 - 1e-09 38.9 0.0 2.9e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 ThiS family Sacchrp_dh_NADP PF03435.18 AJZ75757.1 - 1.5e-06 28.5 1.2 8.1e-06 26.1 1.2 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AJZ75757.1 - 0.0062 16.6 0.2 0.02 14.9 0.1 1.9 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 AJZ75757.1 - 0.076 13.5 0.1 0.26 11.7 0.1 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 AJZ75757.1 - 0.083 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AJZ75757.1 - 0.12 12.9 0.3 4.1 8.1 0.2 3.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.25 AJZ75758.1 - 5.6e-68 229.5 0.3 6.6e-68 229.3 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme C1_2 PF03107.16 AJZ75758.1 - 0.086 13.2 2.2 0.17 12.2 2.2 1.5 1 0 0 1 1 1 0 C1 domain HypA PF01155.19 AJZ75758.1 - 0.25 11.4 0.9 0.52 10.3 0.9 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PRA-CH PF01502.18 AJZ75759.1 - 6.8e-33 112.3 0.1 8.5e-33 112.0 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase His_biosynth PF00977.21 AJZ75760.1 - 1.4e-83 279.9 0.6 1.7e-83 279.6 0.6 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AJZ75760.1 - 1.1e-07 31.2 0.1 0.00042 19.5 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 AJZ75760.1 - 9.9e-07 28.4 0.4 0.0039 16.6 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase TMP-TENI PF02581.17 AJZ75760.1 - 6.2e-06 25.7 0.1 0.039 13.3 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase ThiG PF05690.14 AJZ75760.1 - 0.00039 19.8 0.1 0.25 10.6 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 AJZ75760.1 - 0.0048 16.2 0.0 0.025 13.8 0.0 1.9 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Trp_syntA PF00290.20 AJZ75760.1 - 0.0069 15.3 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain IMPDH PF00478.25 AJZ75760.1 - 0.029 13.4 0.5 0.14 11.1 0.1 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 AJZ75761.1 - 2.6e-67 226.7 2.0 2.9e-67 226.5 2.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein IGPS PF00218.21 AJZ75761.1 - 1.4e-06 27.7 0.1 0.018 14.2 0.0 3.0 2 1 1 3 3 3 2 Indole-3-glycerol phosphate synthase NMO PF03060.15 AJZ75761.1 - 3.4e-05 23.4 0.1 0.031 13.7 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase PcrB PF01884.17 AJZ75761.1 - 0.00089 18.8 0.6 0.55 9.7 0.0 2.5 2 1 1 3 3 3 2 PcrB family ThiG PF05690.14 AJZ75761.1 - 0.0081 15.5 0.1 1.8 7.8 0.0 2.1 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 AJZ75761.1 - 0.024 13.7 0.4 4 6.5 0.1 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF3215 PF11503.8 AJZ75761.1 - 0.052 13.4 0.2 5.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) NanE PF04131.14 AJZ75761.1 - 0.052 12.7 0.1 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.25 AJZ75761.1 - 0.053 12.5 0.2 1.5 7.7 0.1 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain GATase PF00117.28 AJZ75762.1 - 1.3e-21 77.2 0.0 1.5e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJZ75762.1 - 0.0002 21.2 0.0 0.0035 17.1 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AJZ75762.1 - 0.00027 20.8 0.0 0.0033 17.3 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 AJZ75762.1 - 0.0031 17.1 0.0 0.0051 16.4 0.0 1.3 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain IGPD PF00475.18 AJZ75763.1 - 8.6e-48 162.3 0.2 1.2e-47 161.9 0.2 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Hydrolase PF00702.26 AJZ75764.1 - 1.2e-09 38.8 0.0 1.5e-08 35.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AJZ75764.1 - 4.3e-09 36.7 1.9 6.6e-08 32.8 1.9 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF499 PF04465.12 AJZ75764.1 - 0.0094 13.8 0.1 0.013 13.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF499) HAD PF12710.7 AJZ75764.1 - 0.015 15.7 0.0 1.8 8.9 0.0 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AJZ75764.1 - 0.041 13.9 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Acid_phosphat_B PF03767.14 AJZ75764.1 - 0.056 13.0 1.4 0.17 11.4 0.2 2.0 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_6 PF13344.6 AJZ75764.1 - 0.13 12.3 0.8 0.69 10.1 0.1 2.4 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.21 AJZ75765.1 - 2.1e-46 158.8 0.0 2.4e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AJZ75765.1 - 2.1e-06 26.9 0.0 2.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Allinase HTH_22 PF13309.6 AJZ75765.1 - 0.039 14.0 0.1 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 HTH domain Aminotran_5 PF00266.19 AJZ75765.1 - 0.081 11.9 0.0 0.36 9.7 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-V Histidinol_dh PF00815.20 AJZ75766.1 - 6.8e-143 476.6 4.2 8e-143 476.3 4.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase HisG PF01634.18 AJZ75767.1 - 1.6e-43 148.4 0.1 2.1e-43 148.0 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 AJZ75767.1 - 3.1e-15 56.1 0.0 9.4e-15 54.5 0.0 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain HMG-CoA_red PF00368.18 AJZ75768.1 - 5.8e-104 348.0 6.5 6.8e-104 347.8 6.5 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase GSDH PF07995.11 AJZ75769.1 - 4e-83 279.5 0.0 6.2e-83 278.9 0.0 1.3 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 AJZ75769.1 - 0.0014 18.6 0.9 5.7 7.5 0.0 4.1 4 0 0 4 4 4 1 Two component regulator propeller DUF1743 PF08489.11 AJZ75770.1 - 1.9e-34 118.2 0.0 3.7e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1743) ProRS-C_1 PF09180.11 AJZ75770.1 - 0.091 13.0 1.3 0.27 11.5 1.3 1.8 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal C1_1 PF00130.22 AJZ75770.1 - 0.14 12.1 2.6 0.24 11.3 2.6 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 AJZ75770.1 - 0.21 11.6 1.6 0.36 10.9 1.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon Diphthamide_syn PF01866.17 AJZ75771.1 - 3e-61 207.5 0.0 3.5e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein hSH3 PF14603.6 AJZ75772.1 - 0.27 11.7 2.1 0.45 11.0 0.7 1.8 2 0 0 2 2 2 0 Helically-extended SH3 domain ECR1_N PF14382.6 AJZ75773.1 - 6.8e-06 25.8 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region NB PF04159.13 AJZ75773.1 - 0.002 18.1 3.0 0.014 15.5 1.9 2.4 2 1 0 2 2 2 1 NB glycoprotein Prok-RING_1 PF14446.6 AJZ75773.1 - 0.032 14.1 1.2 0.078 12.9 0.7 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.11 AJZ75773.1 - 0.083 12.8 2.3 0.085 12.8 1.1 1.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 AJZ75773.1 - 0.16 11.4 2.2 0.44 10.0 2.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 AJZ75773.1 - 0.2 11.7 1.0 0.45 10.6 1.0 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PDT PF00800.18 AJZ75774.1 - 3.4e-57 193.2 0.0 4.3e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 AJZ75774.1 - 1.2e-05 25.0 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain Ribosomal_S2 PF00318.20 AJZ75775.1 - 0.08 12.2 0.0 0.088 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 PsbN PF02468.15 AJZ75775.1 - 8.2 6.4 6.4 0.7 9.8 1.5 1.7 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) IMPDH PF00478.25 AJZ75776.1 - 1.6e-148 494.3 7.8 1.9e-148 494.1 7.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 AJZ75776.1 - 1.6e-24 86.1 2.9 1.2e-10 41.7 0.5 3.7 3 1 1 4 4 4 2 CBS domain NMO PF03060.15 AJZ75776.1 - 4.1e-11 42.9 4.5 2.1e-07 30.6 1.5 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 AJZ75776.1 - 6e-08 32.1 7.0 9.7e-08 31.4 6.1 1.8 2 1 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 AJZ75776.1 - 1e-05 25.1 1.8 0.013 15.0 0.1 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein DHO_dh PF01180.21 AJZ75776.1 - 0.00033 20.0 3.2 0.0024 17.1 0.5 2.4 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 AJZ75776.1 - 0.0035 16.5 2.5 0.007 15.5 2.5 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 AJZ75776.1 - 0.025 13.9 0.7 0.064 12.6 0.1 2.0 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG B12-binding PF02310.19 AJZ75776.1 - 0.095 12.7 0.2 0.25 11.4 0.2 1.7 1 0 0 1 1 1 0 B12 binding domain G3P_antiterm PF04309.12 AJZ75776.1 - 0.17 11.3 4.2 1.8 8.0 0.0 3.5 3 1 0 4 4 4 0 Glycerol-3-phosphate responsive antiterminator Pterin_bind PF00809.22 AJZ75777.1 - 3.5e-51 174.2 0.0 6.6e-51 173.3 0.0 1.4 1 1 0 1 1 1 1 Pterin binding enzyme BtpA PF03437.15 AJZ75777.1 - 0.099 12.1 0.6 0.92 8.9 0.0 2.1 2 0 0 2 2 2 0 BtpA family Mob_synth_C PF06463.13 AJZ75778.1 - 0.041 13.8 0.4 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C TP53IP5 PF15331.6 AJZ75780.1 - 0.057 13.6 9.6 0.068 13.3 9.6 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Presenilin PF01080.17 AJZ75780.1 - 5.9 5.6 8.4 7 5.3 8.4 1.1 1 0 0 1 1 1 0 Presenilin TPR_8 PF13181.6 AJZ75780.1 - 8.4 6.9 7.3 19 5.8 0.7 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat ROK PF00480.20 AJZ75781.1 - 8.5e-71 238.8 0.7 9.6e-71 238.6 0.7 1.0 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 AJZ75781.1 - 0.00011 21.8 1.4 0.0022 17.5 1.1 2.3 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hydant_A_N PF05378.13 AJZ75781.1 - 0.0018 18.0 0.2 0.003 17.3 0.2 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region FGGY_N PF00370.21 AJZ75781.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain DEDD_Tnp_IS110 PF01548.17 AJZ75781.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Transposase Cpn60_TCP1 PF00118.24 AJZ75782.1 - 5.6e-179 595.9 20.5 6.7e-179 595.6 20.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L44 PF00935.19 AJZ75783.1 - 5.4e-23 81.3 8.0 7.9e-23 80.7 8.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.11 AJZ75783.1 - 0.00074 19.6 7.2 0.001 19.2 0.3 2.1 1 1 1 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like zf-TFIIB PF13453.6 AJZ75783.1 - 0.0011 18.3 0.2 0.38 10.1 0.0 2.3 2 0 0 2 2 2 2 Transcription factor zinc-finger Cys_rich_KTR PF14205.6 AJZ75783.1 - 0.0013 18.5 4.9 0.058 13.2 0.4 2.3 2 0 0 2 2 2 2 Cysteine-rich KTR Zn-ribbon_8 PF09723.10 AJZ75783.1 - 0.011 15.9 1.6 1.8 8.7 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 AJZ75783.1 - 0.011 15.1 3.1 0.99 8.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L33 PF00471.20 AJZ75783.1 - 0.016 15.6 2.0 0.016 15.6 2.0 2.6 2 1 0 2 2 2 0 Ribosomal protein L33 C1_4 PF07975.12 AJZ75783.1 - 0.018 15.2 1.5 0.12 12.6 0.1 2.1 2 0 0 2 2 2 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.7 AJZ75783.1 - 0.027 14.4 0.9 3.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.6 AJZ75783.1 - 0.027 15.1 3.0 0.92 10.2 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS91 PF14319.6 AJZ75783.1 - 0.037 14.1 1.7 5.9 7.0 0.2 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain Nop10p PF04135.12 AJZ75783.1 - 0.079 13.0 4.7 2.3 8.3 0.2 2.3 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family zf-UDP PF14569.6 AJZ75783.1 - 0.094 12.8 6.0 1.2 9.3 1.0 2.3 2 1 0 2 2 2 0 Zinc-binding RING-finger zf-LITAF-like PF10601.9 AJZ75783.1 - 0.096 13.0 2.9 4.4 7.6 0.2 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zinc_ribbon_10 PF10058.9 AJZ75783.1 - 0.19 11.4 1.8 3.2 7.6 0.1 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-RING_4 PF14570.6 AJZ75783.1 - 0.2 11.5 3.4 7.8 6.4 0.4 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain YacG PF03884.14 AJZ75783.1 - 0.24 11.2 2.7 3.8 7.3 0.3 2.3 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG DZR PF12773.7 AJZ75783.1 - 0.34 11.0 5.9 1.4 9.0 5.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 AJZ75783.1 - 0.39 10.4 3.9 2.7 7.7 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 AJZ75783.1 - 1.2 9.7 9.4 0.27 11.7 1.6 2.6 3 0 0 3 3 2 0 Zinc-finger double domain zinc_ribbon_4 PF13717.6 AJZ75783.1 - 1.2 9.1 7.8 2.9 7.9 1.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 AJZ75783.1 - 1.6 8.3 6.7 11 5.6 0.4 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger Ribosomal_S27e PF01667.17 AJZ75784.1 - 3e-16 58.9 2.0 3.3e-16 58.7 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 AJZ75784.1 - 2.4e-07 30.2 0.7 3.1e-07 29.8 0.7 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RING_9 PF13901.6 AJZ75784.1 - 0.0051 16.8 0.9 0.0056 16.7 0.9 1.0 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon zinc_ribbon_6 PF14599.6 AJZ75784.1 - 0.0097 15.9 1.8 0.013 15.4 1.8 1.2 1 0 0 1 1 1 1 Zinc-ribbon Zn_Tnp_IS91 PF14319.6 AJZ75784.1 - 0.012 15.6 0.6 0.014 15.4 0.6 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain zinc_ribbon_4 PF13717.6 AJZ75784.1 - 0.018 15.0 4.9 0.7 9.9 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.9 AJZ75784.1 - 0.02 15.0 0.2 0.022 14.9 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) HECT_2 PF09814.9 AJZ75784.1 - 0.11 11.3 2.6 0.4 9.5 2.6 1.7 1 1 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zinc_ribbon_12 PF11331.8 AJZ75784.1 - 0.2 11.5 5.0 1.3 8.9 1.0 2.1 1 1 2 3 3 3 0 Probable zinc-ribbon domain zf_UBZ PF18439.1 AJZ75784.1 - 0.36 10.5 2.9 2.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DNA_RNApol_7kD PF03604.13 AJZ75784.1 - 0.57 9.9 4.6 5.5 6.8 0.4 2.1 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit TFIIS_C PF01096.18 AJZ75784.1 - 0.79 9.6 6.2 63 3.5 6.2 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) zf-C2H2_3 PF13878.6 AJZ75784.1 - 1.6 8.6 9.6 1.5 8.7 1.7 2.2 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-BED PF02892.15 AJZ75784.1 - 1.8 8.7 6.2 2.9 8.0 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger zinc_ribbon_13 PF09855.9 AJZ75784.1 - 2.3 8.4 6.9 9.7 6.4 0.7 2.2 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) NTP_transf_3 PF12804.7 AJZ75785.1 - 7e-14 52.5 0.0 8.5e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AJZ75785.1 - 3.5e-07 30.2 0.0 4.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 AJZ75785.1 - 3.7e-07 30.3 0.1 5.3e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transferase PF00483.23 AJZ75785.1 - 0.0082 15.7 0.0 0.025 14.1 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyl transferase Sgf11_N PF18519.1 AJZ75785.1 - 0.14 11.7 1.1 5.1 6.7 0.5 2.3 1 1 1 2 2 2 0 SAGA-associated factor 11 N-terminal domain CobD_Cbib PF03186.13 AJZ75786.1 - 2.2e-83 279.6 0.3 2.9e-83 279.3 0.3 1.1 1 0 0 1 1 1 1 CobD/Cbib protein CbiA PF01656.23 AJZ75787.1 - 1.1e-21 77.2 0.0 5.8e-21 74.9 0.0 1.9 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AJZ75787.1 - 8.3e-19 68.2 0.2 1.7e-17 63.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 AJZ75787.1 - 2e-06 27.9 0.0 1.1e-05 25.4 0.0 2.2 2 1 2 4 4 4 1 NTPase MobB PF03205.14 AJZ75787.1 - 1.7e-05 24.7 0.1 0.00075 19.4 0.0 2.7 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B CBP_BcsQ PF06564.12 AJZ75787.1 - 0.00013 21.5 0.0 0.00031 20.3 0.0 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 AJZ75787.1 - 0.00036 20.2 0.9 0.076 12.6 0.1 2.5 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain AAA_23 PF13476.6 AJZ75787.1 - 0.00082 19.9 0.9 0.0035 17.9 0.9 1.9 1 1 0 1 1 1 1 AAA domain VirC1 PF07015.11 AJZ75787.1 - 0.0076 15.6 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 VirC1 protein ABC_tran PF00005.27 AJZ75787.1 - 0.0079 16.7 0.1 0.018 15.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 AJZ75787.1 - 0.023 15.1 0.0 0.036 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_31 PF13614.6 AJZ75787.1 - 0.026 14.4 3.1 0.028 14.3 0.3 2.4 2 1 1 3 3 3 0 AAA domain cobW PF02492.19 AJZ75787.1 - 0.04 13.5 0.9 0.69 9.5 0.0 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 AJZ75787.1 - 0.052 13.3 0.2 0.14 11.8 0.1 1.7 2 1 0 2 2 2 0 AAA domain CTP_synth_N PF06418.14 AJZ75787.1 - 0.055 12.8 0.1 0.34 10.2 0.1 2.0 2 0 0 2 2 2 0 CTP synthase N-terminus APS_kinase PF01583.20 AJZ75787.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF1611 PF07755.11 AJZ75787.1 - 0.12 11.7 0.0 0.57 9.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain Aminotran_1_2 PF00155.21 AJZ75788.1 - 2e-51 175.3 0.0 2.5e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AJZ75788.1 - 0.027 13.0 0.0 0.043 12.3 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Semialdhyde_dhC PF02774.18 AJZ75789.1 - 2.1e-37 129.0 0.0 3.6e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AJZ75789.1 - 7.5e-29 100.6 0.0 1.4e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 AJZ75789.1 - 5e-05 23.0 1.5 0.00051 19.7 0.0 2.6 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.16 AJZ75789.1 - 0.0074 17.0 0.0 0.03 15.1 0.0 2.0 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ldh_1_N PF00056.23 AJZ75789.1 - 0.065 13.3 0.0 0.3 11.2 0.0 2.1 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain AsnC_trans_reg PF01037.21 AJZ75790.1 - 2.5e-09 37.0 0.0 2.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain UbiA PF01040.18 AJZ75791.1 - 3.5e-40 137.9 18.2 4.7e-40 137.5 18.2 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family EutH PF04346.12 AJZ75791.1 - 0.011 14.9 5.4 0.016 14.4 5.4 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH Tetraspanin PF00335.20 AJZ75791.1 - 0.21 11.3 3.8 0.39 10.4 2.8 1.9 1 1 0 1 1 1 0 Tetraspanin family DUF3180 PF11377.8 AJZ75791.1 - 0.52 10.4 7.3 0.036 14.2 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) EXS PF03124.14 AJZ75791.1 - 2.4 7.4 11.5 0.31 10.3 5.9 2.0 2 1 0 2 2 2 0 EXS family DUF2189 PF09955.9 AJZ75791.1 - 5.5 7.3 18.8 0.087 13.1 3.7 3.4 3 1 1 4 4 4 0 Predicted integral membrane protein (DUF2189) HTH_CodY PF08222.11 AJZ75792.1 - 4.2e-05 23.0 0.0 7.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 CodY helix-turn-helix domain HTH_11 PF08279.12 AJZ75792.1 - 0.021 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 HTH domain FtsK_gamma PF09397.10 AJZ75792.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Ftsk gamma domain HTH_27 PF13463.6 AJZ75792.1 - 0.17 12.4 0.0 0.25 11.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF2802 PF10975.8 AJZ75794.1 - 0.0017 18.4 3.2 0.0052 16.9 0.9 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2802) ORF6C PF10552.9 AJZ75794.1 - 0.01 15.9 2.2 0.012 15.7 2.2 1.0 1 0 0 1 1 1 0 ORF6C domain Cnd1 PF12717.7 AJZ75794.1 - 0.012 15.7 1.9 0.013 15.5 1.9 1.0 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 KIAA1328 PF15369.6 AJZ75794.1 - 0.014 15.3 4.4 0.015 15.1 4.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 FliD_C PF07195.12 AJZ75794.1 - 0.017 14.5 2.2 0.019 14.4 1.0 1.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus E2_bind PF08825.10 AJZ75794.1 - 0.046 13.9 2.8 2 8.6 0.2 2.8 1 1 2 3 3 3 0 E2 binding domain Ribosomal_S20p PF01649.18 AJZ75794.1 - 0.062 13.9 0.8 0.078 13.6 0.8 1.2 1 0 0 1 1 1 0 Ribosomal protein S20 Noelin-1 PF12308.8 AJZ75794.1 - 0.065 13.2 1.5 0.1 12.6 1.5 1.4 1 1 0 1 1 1 0 Neurogenesis glycoprotein ParB PF08775.10 AJZ75794.1 - 0.068 13.7 4.4 0.072 13.6 4.4 1.0 1 0 0 1 1 1 0 ParB family CLZ PF16526.5 AJZ75794.1 - 0.097 13.0 7.0 3.8 7.9 6.6 2.2 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_TATA_bd PF12325.8 AJZ75794.1 - 0.12 12.6 8.9 0.14 12.3 8.9 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Lge1 PF11488.8 AJZ75794.1 - 0.15 12.3 6.9 0.25 11.6 5.7 2.0 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF1664 PF07889.12 AJZ75794.1 - 0.17 12.0 3.6 0.19 11.7 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ApoC-I PF04691.12 AJZ75794.1 - 0.17 11.9 3.2 0.16 11.9 1.2 2.0 2 1 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Tropomyosin_1 PF12718.7 AJZ75794.1 - 0.18 11.9 11.3 0.39 10.9 11.3 1.5 1 1 0 1 1 1 0 Tropomyosin like PIN_2 PF10130.9 AJZ75794.1 - 0.18 12.0 2.6 0.21 11.8 2.6 1.0 1 0 0 1 1 1 0 PIN domain CENP-H PF05837.12 AJZ75794.1 - 0.25 11.8 6.8 0.29 11.6 6.8 1.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4094 PF13334.6 AJZ75794.1 - 0.25 11.8 2.0 0.59 10.6 2.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Fzo_mitofusin PF04799.13 AJZ75794.1 - 0.29 10.7 4.4 0.37 10.3 4.4 1.2 1 0 0 1 1 1 0 fzo-like conserved region Fib_alpha PF08702.10 AJZ75794.1 - 0.29 11.3 4.5 0.44 10.7 2.4 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 AJZ75794.1 - 0.3 9.0 2.8 0.34 8.8 2.8 1.0 1 0 0 1 1 1 0 Prominin XhlA PF10779.9 AJZ75794.1 - 0.45 10.8 7.4 0.57 10.4 2.5 2.1 1 1 1 2 2 2 0 Haemolysin XhlA TMPIT PF07851.13 AJZ75794.1 - 0.67 9.1 5.1 0.66 9.2 5.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF724 PF05266.14 AJZ75794.1 - 1.2 8.9 7.8 1.3 8.8 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Packaging_FI PF14000.6 AJZ75794.1 - 1.5 9.3 7.5 3.8 8.0 1.5 2.1 1 1 1 2 2 2 0 DNA packaging protein FI ZapB PF06005.12 AJZ75794.1 - 1.7 9.2 11.6 0.3 11.6 5.3 2.0 1 1 1 2 2 2 0 Cell division protein ZapB YabA PF06156.13 AJZ75794.1 - 1.7 9.3 6.9 2.5 8.8 6.9 1.3 1 1 0 1 1 1 0 Initiation control protein YabA MRPL52 PF18699.1 AJZ75794.1 - 1.8 8.8 6.8 1.3 9.2 4.3 1.8 1 1 1 2 2 2 0 Mitoribosomal protein mL52 Trimer_CC PF08954.11 AJZ75794.1 - 2.6 7.7 6.5 3 7.5 0.1 2.6 3 0 0 3 3 3 0 Trimerisation motif WD40_alt PF14077.6 AJZ75794.1 - 2.8 7.9 7.6 17 5.4 0.1 2.6 2 1 1 3 3 3 0 Alternative WD40 repeat motif bZIP_2 PF07716.15 AJZ75794.1 - 2.9 8.1 10.5 3.2 7.9 6.5 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DNA_repr_REX1B PF14966.6 AJZ75797.1 - 0.014 16.0 4.1 0.045 14.4 4.1 1.9 1 1 0 1 1 1 0 DNA repair REX1-B Tape_meas_lam_C PF09718.10 AJZ75797.1 - 0.016 15.3 6.8 0.025 14.7 1.3 2.6 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) rve PF00665.26 AJZ75797.1 - 0.05 13.8 0.2 0.081 13.1 0.2 1.4 1 1 0 1 1 1 0 Integrase core domain Phasin_2 PF09361.10 AJZ75797.1 - 0.073 13.4 5.7 0.7 10.2 2.0 2.6 1 1 0 2 2 2 0 Phasin protein SEC-C PF02810.15 AJZ75798.1 - 0.016 15.1 8.6 0.023 14.6 8.6 1.3 1 0 0 1 1 1 0 SEC-C motif FCH PF00611.23 AJZ75798.1 - 0.035 14.4 0.0 0.22 11.9 0.0 2.0 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain rRNA_methylase PF06962.12 AJZ75799.1 - 0.067 13.2 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Putative rRNA methylase P-II PF00543.22 AJZ75800.1 - 6.9e-12 45.9 1.6 7.7e-12 45.7 1.6 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF190 PF02641.15 AJZ75800.1 - 2.6e-05 24.4 0.1 3.7e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1993 Nit_Regul_Hom PF10126.9 AJZ75800.1 - 0.014 15.4 1.3 0.043 13.8 1.3 1.7 1 1 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII Gp_dh_C PF02800.20 AJZ75800.1 - 0.021 14.4 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain CBS PF00571.28 AJZ75801.1 - 3.5e-40 136.2 14.2 2.2e-11 44.0 0.4 4.1 4 0 0 4 4 4 4 CBS domain Ammonium_transp PF00909.21 AJZ75802.1 - 8.6e-112 373.7 30.8 9.8e-112 373.5 30.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3188 PF11384.8 AJZ75802.1 - 2 8.2 9.1 0.81 9.4 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) P-II PF00543.22 AJZ75803.1 - 7.9e-13 48.9 0.3 9.7e-13 48.6 0.3 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Usp PF00582.26 AJZ75805.1 - 4e-31 108.4 0.0 4.7e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family CBS PF00571.28 AJZ75807.1 - 2.4e-44 149.6 6.3 2.6e-11 43.8 0.1 4.1 4 0 0 4 4 4 4 CBS domain DUF4539 PF15072.6 AJZ75807.1 - 0.068 13.2 1.9 10 6.3 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4539) CopG_antitoxin PF12441.8 AJZ75808.1 - 0.00015 22.2 0.3 0.00063 20.2 0.1 2.0 2 0 0 2 2 2 1 CopG antitoxin of type II toxin-antitoxin system RnlB_antitoxin PF15933.5 AJZ75808.1 - 0.11 12.8 0.1 0.51 10.7 0.0 2.0 2 1 0 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA HicB PF05534.12 AJZ75808.1 - 0.15 11.9 0.6 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 HicB family CBS PF00571.28 AJZ75809.1 - 2e-20 73.0 3.4 2.5e-08 34.2 0.2 4.4 4 0 0 4 4 4 4 CBS domain ChapFlgA PF13144.6 AJZ75809.1 - 0.047 13.8 0.6 11 6.2 0.1 2.7 1 1 0 2 2 2 0 Chaperone for flagella basal body P-ring formation Copper-bind PF00127.20 AJZ75810.1 - 5.2e-07 30.0 0.2 7.6e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJZ75810.1 - 1.9e-05 24.7 0.2 3e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain Minor_tail_Z PF06763.11 AJZ75810.1 - 0.068 13.0 0.0 0.09 12.6 0.0 1.1 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) HTH_52 PF18576.1 AJZ75810.1 - 0.082 13.1 0.2 0.19 12.0 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain adh_short_C2 PF13561.6 AJZ75811.1 - 2.8e-59 200.5 1.7 3.2e-59 200.3 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AJZ75811.1 - 2.6e-51 173.8 3.1 3.2e-51 173.6 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AJZ75811.1 - 3.3e-08 33.7 0.9 4.8e-08 33.1 0.9 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AJZ75811.1 - 1.9e-05 24.2 0.1 2.7e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 AJZ75811.1 - 6.3e-05 22.5 1.4 0.00017 21.1 1.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 AJZ75811.1 - 0.025 13.9 0.5 0.078 12.3 0.1 2.0 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 AJZ75811.1 - 0.07 12.2 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain TIG PF01833.24 AJZ75811.1 - 0.096 12.8 0.1 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 IPT/TIG domain Usp PF00582.26 AJZ75812.1 - 8.7e-29 100.8 0.0 1.1e-28 100.5 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF1400 PF07176.11 AJZ75812.1 - 0.091 13.0 0.0 0.21 11.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) Pribosyltran PF00156.27 AJZ75813.1 - 2.7e-10 40.0 0.0 0.00019 21.0 0.0 2.1 1 1 1 2 2 2 2 Phosphoribosyl transferase domain CBS PF00571.28 AJZ75814.1 - 5.3e-28 97.2 7.0 5.7e-15 55.5 0.2 2.1 2 0 0 2 2 2 2 CBS domain Flavi_NS2A PF01005.19 AJZ75814.1 - 0.081 13.1 1.3 9.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2A DUF5049 PF16468.5 AJZ75815.1 - 0.083 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) Usp PF00582.26 AJZ75817.1 - 7.8e-29 101.0 0.0 8.9e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 AJZ75818.1 - 4.7e-30 104.9 0.1 6.4e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family Beta_elim_lyase PF01212.21 AJZ75818.1 - 0.092 12.0 0.1 0.18 11.0 0.1 1.5 1 1 1 2 2 2 0 Beta-eliminating lyase Pribosyltran PF00156.27 AJZ75819.1 - 2.5e-22 79.1 0.0 3.8e-22 78.5 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AJZ75819.1 - 5.8e-05 22.6 0.0 9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AJZ75819.1 - 0.00012 21.6 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase Usp PF00582.26 AJZ75820.1 - 2.7e-30 105.7 0.0 3e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family GARS_N PF02844.15 AJZ75820.1 - 0.12 13.2 0.0 0.3 11.9 0.0 1.8 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain CBS PF00571.28 AJZ75821.1 - 6.7e-24 84.1 2.0 5e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 CBS domain VIT1 PF01988.19 AJZ75822.1 - 1.1e-56 192.1 1.2 1.2e-56 192.0 1.2 1.0 1 0 0 1 1 1 1 VIT family GH-E PF14410.6 AJZ75822.1 - 0.14 12.6 0.1 0.21 12.0 0.1 1.2 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues PGG PF13962.6 AJZ75822.1 - 3 7.7 8.4 0.33 10.8 3.7 1.8 2 0 0 2 2 2 0 Domain of unknown function Bep_C_terminal PF17841.1 AJZ75823.1 - 0.0025 18.0 5.7 0.11 12.8 0.5 2.8 1 1 1 2 2 2 2 BID domain of Bartonella effector protein (Bep) Calreticulin PF00262.18 AJZ75823.1 - 0.0035 16.3 0.2 0.0051 15.7 0.2 1.3 1 0 0 1 1 1 1 Calreticulin family DUF4064 PF13273.6 AJZ75823.1 - 0.025 14.9 0.9 0.025 14.9 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) ApoL PF05461.11 AJZ75823.1 - 0.096 12.0 2.3 0.11 11.8 0.4 1.9 2 1 0 2 2 2 0 Apolipoprotein L DUF3810 PF12725.7 AJZ75823.1 - 0.55 9.5 8.0 0.19 11.0 4.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) TFIIA PF03153.13 AJZ75823.1 - 1.2 9.0 10.9 1.5 8.8 10.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit XPC-binding PF09280.11 AJZ75823.1 - 2.8 7.7 32.7 1 9.1 7.0 3.7 1 1 2 3 3 3 0 XPC-binding domain DUF3467 PF11950.8 AJZ75823.1 - 5 7.4 7.1 5.4 7.3 1.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3467) Aminotran_1_2 PF00155.21 AJZ75823.1 - 9.4 5.3 8.4 33 3.5 8.4 1.8 1 1 0 1 1 1 0 Aminotransferase class I and II Cpn60_TCP1 PF00118.24 AJZ75824.1 - 9.2e-182 605.0 20.9 1.1e-181 604.8 20.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PALP PF00291.25 AJZ75824.1 - 0.011 15.1 0.2 1.9 7.8 0.0 2.8 2 1 1 3 3 3 0 Pyridoxal-phosphate dependent enzyme DUF3924 PF13062.6 AJZ75824.1 - 0.022 14.7 0.3 0.19 11.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) Ustilago_mating PF05722.12 AJZ75824.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Ldh_1_N PF00056.23 AJZ75825.1 - 7.1e-24 84.5 2.3 1.5e-23 83.5 1.7 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AJZ75825.1 - 4.2e-23 82.1 0.0 6.4e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 AJZ75825.1 - 4.2e-06 26.5 1.4 0.001 18.6 0.0 2.9 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase F420_oxidored PF03807.17 AJZ75825.1 - 0.00071 20.1 0.5 0.0019 18.7 0.4 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 AJZ75825.1 - 0.0065 16.5 0.2 0.012 15.7 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AJZ75825.1 - 0.0082 16.4 0.1 0.015 15.6 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 AJZ75825.1 - 0.02 14.9 0.9 0.1 12.6 0.2 2.4 2 1 1 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DDE_Tnp_1_assoc PF13808.6 AJZ75825.1 - 0.063 13.3 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 DDE_Tnp_1-associated UDPG_MGDP_dh_N PF03721.14 AJZ75825.1 - 0.072 12.7 3.0 0.48 10.0 3.0 2.1 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 AJZ75825.1 - 0.18 11.7 1.1 0.32 10.8 0.2 2.0 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cupredoxin_1 PF13473.6 AJZ75826.1 - 0.00012 22.2 0.2 0.00026 21.1 0.2 1.6 1 1 1 2 2 2 1 Cupredoxin-like domain DUF1905 PF08922.11 AJZ75826.1 - 0.045 13.8 0.0 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) ELFV_dehydrog PF00208.21 AJZ75826.1 - 0.079 12.7 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AA_permease_2 PF13520.6 AJZ75828.1 - 1.3e-54 185.6 56.4 1.6e-54 185.4 56.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AJZ75828.1 - 2.5e-43 148.4 51.1 3.2e-43 148.0 51.1 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 AJZ75828.1 - 1.9e-10 40.1 30.7 3.6e-08 32.5 19.1 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Spore_permease PF03845.13 AJZ75828.1 - 3.2e-08 32.8 23.7 3.2e-08 32.8 23.7 2.6 1 1 1 2 2 2 2 Spore germination protein DUF2152 PF10222.9 AJZ75828.1 - 0.051 11.9 0.1 0.093 11.0 0.1 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2152) TMEM237 PF15383.6 AJZ75828.1 - 1.7 7.7 6.1 0.09 11.9 0.6 1.7 2 0 0 2 2 2 0 Transmembrane protein 237 Nramp PF01566.18 AJZ75829.1 - 2.8e-72 243.7 20.8 3.4e-72 243.4 20.8 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF5383 PF17355.2 AJZ75829.1 - 0.73 10.2 0.0 0.73 10.2 0.0 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5383) Glycophorin_A PF01102.18 AJZ75829.1 - 5.5 7.3 5.1 19 5.5 0.0 3.1 2 1 1 3 3 3 0 Glycophorin A Thioredoxin_4 PF13462.6 AJZ75830.1 - 9.9e-28 97.4 0.0 1.2e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AJZ75830.1 - 1.1e-12 48.1 0.1 1.5e-10 41.2 0.1 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJZ75830.1 - 0.00019 21.9 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AJZ75830.1 - 0.0087 16.4 0.0 0.13 12.6 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like DUF2070 PF09843.9 AJZ75831.1 - 9.8 4.3 14.9 10 4.3 14.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4423 PF14394.6 AJZ75833.1 - 0.037 13.7 0.1 0.039 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) SelB-wing_2 PF09106.11 AJZ75833.1 - 0.05 13.8 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Prok-RING_4 PF14447.6 AJZ75834.1 - 0.00015 21.5 0.5 0.037 13.9 0.1 2.1 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 AJZ75834.1 - 0.00067 19.5 0.8 0.15 11.9 0.2 2.1 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 AJZ75834.1 - 0.0014 18.9 0.4 0.6 10.4 0.1 2.1 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 AJZ75834.1 - 0.0019 18.0 0.8 0.47 10.3 0.0 2.2 2 0 0 2 2 2 2 Rad50 zinc hook motif GAGA PF09237.11 AJZ75834.1 - 0.0043 16.8 2.2 1.3 8.9 0.1 2.1 2 0 0 2 2 2 2 GAGA factor zf-Sec23_Sec24 PF04810.15 AJZ75834.1 - 0.014 15.5 1.5 3.3 7.8 0.4 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.10 AJZ75834.1 - 0.018 15.2 0.3 2.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Prok-RING_1 PF14446.6 AJZ75834.1 - 0.019 14.9 0.5 0.81 9.7 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 AJZ75834.1 - 0.033 14.1 0.9 3.7 7.6 0.1 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-BED PF02892.15 AJZ75834.1 - 0.051 13.6 0.5 0.54 10.3 0.1 2.1 2 0 0 2 2 2 0 BED zinc finger Sgf11 PF08209.11 AJZ75834.1 - 0.06 12.9 0.2 0.06 12.9 0.2 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) CTU2 PF10288.9 AJZ75834.1 - 0.067 13.4 1.0 0.23 11.7 1.0 1.8 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 NADH-G_4Fe-4S_3 PF10588.9 AJZ75834.1 - 0.089 12.3 0.9 10 5.7 0.2 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C2H2_3 PF13878.6 AJZ75834.1 - 0.11 12.3 0.6 4.9 7.1 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-H2C2_2 PF13465.6 AJZ75834.1 - 0.12 12.8 2.3 2.3 8.8 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double domain DUF2225 PF09986.9 AJZ75834.1 - 0.17 11.6 1.5 3.3 7.4 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-WRNIP1_ubi PF18279.1 AJZ75834.1 - 0.17 12.6 2.6 8.3 7.3 0.2 2.3 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Zn-C2H2_12 PF18112.1 AJZ75834.1 - 0.24 11.9 3.6 12 6.5 0.2 2.3 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF5531 PF17671.1 AJZ75835.1 - 0.018 14.9 0.2 0.027 14.3 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5531) MAP70 PF07058.11 AJZ75835.1 - 0.049 12.4 0.2 0.079 11.7 0.2 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 HNOB PF07700.15 AJZ75835.1 - 0.061 13.3 0.1 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Haem-NO-binding ECF_trnsprt PF12822.7 AJZ75836.1 - 0.00072 19.7 0.8 0.00078 19.6 0.8 1.0 1 0 0 1 1 1 1 ECF transporter, substrate-specific component SLATT_1 PF18181.1 AJZ75836.1 - 0.025 14.5 0.2 1.4 8.9 0.0 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 RseC_MucC PF04246.12 AJZ75836.1 - 0.18 11.7 0.3 0.24 11.4 0.3 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Wzz PF02706.15 AJZ75836.1 - 0.44 10.9 0.1 0.44 10.9 0.1 1.8 2 0 0 2 2 2 0 Chain length determinant protein UbiD PF01977.16 AJZ75837.1 - 9.1e-91 304.7 0.2 1e-90 304.5 0.2 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF4451 PF14616.6 AJZ75839.1 - 0.084 13.1 0.4 0.17 12.1 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) RuvX PF03652.15 AJZ75840.1 - 0.0066 16.8 0.1 0.078 13.4 0.1 2.1 1 1 0 1 1 1 1 Holliday junction resolvase DUF460 PF04312.13 AJZ75840.1 - 0.11 12.2 0.2 0.27 10.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF460) DUF883 PF05957.13 AJZ75841.1 - 0.00015 22.2 6.9 0.0035 17.9 4.4 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Muted PF14942.6 AJZ75841.1 - 0.002 18.5 6.1 0.0031 17.9 6.1 1.3 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein V-ATPase_G_2 PF16999.5 AJZ75841.1 - 0.0023 18.3 9.9 0.0047 17.3 6.3 2.6 1 1 1 2 2 2 1 Vacuolar (H+)-ATPase G subunit APP_E2 PF12925.7 AJZ75841.1 - 0.0025 17.6 2.8 0.073 12.8 0.3 2.0 1 1 1 2 2 2 1 E2 domain of amyloid precursor protein Apolipoprotein PF01442.18 AJZ75841.1 - 0.003 17.5 4.5 0.012 15.5 4.5 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DivIVA PF05103.13 AJZ75841.1 - 0.011 15.8 9.2 0.017 15.2 9.2 1.3 1 1 0 1 1 1 0 DivIVA protein V-SNARE PF05008.15 AJZ75841.1 - 0.012 15.9 9.2 0.12 12.8 2.3 2.4 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus ISG65-75 PF11727.8 AJZ75841.1 - 0.016 14.5 7.4 0.019 14.2 7.4 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Phage_Mu_Gam PF07352.12 AJZ75841.1 - 0.031 14.2 8.8 0.15 12.0 0.4 2.0 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Exonuc_VII_L PF02601.15 AJZ75841.1 - 0.033 13.8 3.3 0.036 13.6 3.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit STAT_alpha PF01017.20 AJZ75841.1 - 0.055 13.4 4.0 0.072 13.0 4.0 1.3 1 1 0 1 1 1 0 STAT protein, all-alpha domain ATP-synt_B PF00430.18 AJZ75841.1 - 0.056 13.5 8.6 0.14 12.2 7.7 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) CsoSCA PF08936.10 AJZ75841.1 - 0.057 12.1 0.6 0.063 11.9 0.6 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase COG6 PF06419.11 AJZ75841.1 - 0.059 11.6 6.8 0.15 10.2 6.8 1.6 1 1 0 1 1 1 0 Conserved oligomeric complex COG6 KxDL PF10241.9 AJZ75841.1 - 0.061 13.6 3.4 0.11 12.8 0.3 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein V-ATPase_G PF03179.15 AJZ75841.1 - 0.064 13.8 8.2 0.11 13.0 7.4 1.9 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Tweety PF04906.13 AJZ75841.1 - 0.083 11.5 1.4 0.096 11.3 1.4 1.1 1 0 0 1 1 1 0 Tweety DASH_Dam1 PF08653.10 AJZ75841.1 - 0.083 12.7 1.2 2.7 7.9 0.4 2.7 2 1 1 3 3 3 0 DASH complex subunit Dam1 Fez1 PF06818.15 AJZ75841.1 - 0.087 13.3 6.2 0.096 13.1 6.2 1.1 1 0 0 1 1 1 0 Fez1 DUF1682 PF07946.14 AJZ75841.1 - 0.092 11.9 5.6 0.11 11.7 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF5398 PF17376.2 AJZ75841.1 - 0.093 13.4 2.2 0.11 13.2 1.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5398) Phasin PF05597.11 AJZ75841.1 - 0.098 12.7 8.8 0.67 10.0 3.9 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SlyX PF04102.12 AJZ75841.1 - 0.099 13.3 2.0 0.73 10.5 2.0 2.1 1 1 0 1 1 1 0 SlyX Baculo_PEP_C PF04513.12 AJZ75841.1 - 0.16 12.0 3.5 0.33 11.0 1.4 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 AJZ75841.1 - 0.16 12.1 10.1 1.6 8.9 10.2 2.1 1 1 0 1 1 1 0 Tropomyosin like ZYG-11_interact PF05884.12 AJZ75841.1 - 0.17 11.3 2.6 0.21 11.0 2.1 1.3 1 1 0 1 1 1 0 Interactor of ZYG-11 Peptidase_M41 PF01434.18 AJZ75841.1 - 0.18 11.6 5.1 0.16 11.8 3.6 1.6 1 1 1 2 2 2 0 Peptidase family M41 DUF2746 PF10874.8 AJZ75841.1 - 0.24 11.8 6.4 4.5 7.8 0.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2746) Ku_C PF03730.14 AJZ75841.1 - 0.28 11.9 3.1 0.38 11.5 3.1 1.4 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm YabA PF06156.13 AJZ75841.1 - 0.3 11.8 3.2 0.5 11.0 3.2 1.4 1 1 0 1 1 1 0 Initiation control protein YabA Allexi_40kDa PF05549.11 AJZ75841.1 - 0.35 10.4 3.8 0.46 9.9 3.8 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein YtxH PF12732.7 AJZ75841.1 - 0.36 11.4 12.1 3.3 8.3 2.0 2.3 1 1 1 2 2 2 0 YtxH-like protein Prominin PF05478.11 AJZ75841.1 - 0.36 8.7 3.9 0.51 8.2 3.9 1.2 1 0 0 1 1 1 0 Prominin NPV_P10 PF05531.12 AJZ75841.1 - 0.45 11.0 5.5 1.2 9.7 5.5 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.17 AJZ75841.1 - 0.45 10.4 9.6 0.26 11.2 0.5 2.7 1 1 2 3 3 3 0 Prefoldin subunit Spc24 PF08286.11 AJZ75841.1 - 0.47 10.7 8.1 3.8 7.8 8.1 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Uso1_p115_C PF04871.13 AJZ75841.1 - 0.51 10.7 11.9 2.5 8.5 11.9 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 AJZ75841.1 - 0.89 9.6 6.7 0.88 9.6 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HSCB_C PF07743.13 AJZ75841.1 - 0.94 10.0 6.8 5.4 7.6 1.1 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain XhlA PF10779.9 AJZ75841.1 - 1.3 9.2 9.2 0.21 11.8 2.4 2.4 1 1 1 2 2 2 0 Haemolysin XhlA PKI PF02827.16 AJZ75841.1 - 1.4 9.2 6.1 2.2 8.6 1.7 2.2 1 1 1 2 2 2 0 cAMP-dependent protein kinase inhibitor FlaC_arch PF05377.11 AJZ75841.1 - 1.7 9.1 9.3 0.29 11.5 2.6 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.9 AJZ75841.1 - 2 9.1 5.6 11 6.8 3.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) RNase_J_C PF17770.1 AJZ75841.1 - 2.4 9.2 5.1 1.6 9.8 1.2 2.2 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain TMPIT PF07851.13 AJZ75841.1 - 5.3 6.2 8.3 16 4.6 8.3 1.7 1 1 0 1 1 1 0 TMPIT-like protein NAC PF01849.18 AJZ75842.1 - 5.8e-14 51.8 1.7 4e-13 49.1 1.3 2.0 2 0 0 2 2 2 1 NAC domain UBA_4 PF14555.6 AJZ75842.1 - 0.06 13.2 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain PhnI PF05861.12 AJZ75842.1 - 0.1 11.4 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) PhoU PF01895.19 AJZ75843.1 - 6.1e-26 90.7 17.2 1.6e-18 66.9 2.1 3.0 3 0 0 3 3 3 2 PhoU domain MazE_antitoxin PF04014.18 AJZ75843.1 - 8.7e-10 38.3 0.2 2e-08 34.0 0.0 2.6 2 0 0 2 2 2 1 Antidote-toxin recognition MazE, bacterial antitoxin HemY_N PF07219.13 AJZ75843.1 - 0.031 14.5 0.1 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 HemY protein N-terminus Erythro_esteras PF05139.14 AJZ75843.1 - 0.072 12.9 0.4 0.1 12.4 0.4 1.2 1 0 0 1 1 1 0 Erythromycin esterase GTP-bdg_N PF13167.6 AJZ75844.1 - 1.6e-19 70.4 0.3 9.9e-19 67.8 0.0 2.4 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 AJZ75844.1 - 5.4e-15 55.5 0.1 1.1e-14 54.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_M PF16360.5 AJZ75844.1 - 1.2e-14 54.7 1.3 3e-14 53.4 1.3 1.7 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region RsgA_GTPase PF03193.16 AJZ75844.1 - 2.9e-06 27.3 4.2 0.00016 21.6 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 AJZ75844.1 - 7.5e-06 25.5 0.1 1.6e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 AJZ75844.1 - 0.00058 19.4 1.5 0.028 13.9 1.5 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 AJZ75844.1 - 0.011 16.2 0.1 0.043 14.3 0.0 2.1 3 1 0 3 3 3 0 ABC transporter MMR_HSR1_Xtn PF16897.5 AJZ75844.1 - 0.012 15.7 0.1 0.034 14.1 0.1 1.9 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 AJZ75844.1 - 0.017 14.9 1.4 0.11 12.2 1.0 2.5 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AsnC_trans_reg PF01037.21 AJZ75846.1 - 1.8e-08 34.2 0.0 2.1e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GYD PF08734.11 AJZ75846.1 - 0.00076 19.4 0.0 0.00085 19.2 0.0 1.1 1 0 0 1 1 1 1 GYD domain RibD_C PF01872.17 AJZ75847.1 - 3.1e-51 174.1 0.3 3.4e-51 173.9 0.3 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Amidohydro_1 PF01979.20 AJZ75848.1 - 5e-45 154.3 1.8 5.8e-45 154.1 1.8 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AJZ75848.1 - 9.6e-17 61.6 0.2 5.3e-10 39.4 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family GCH_III PF05165.12 AJZ75849.1 - 2.2e-51 174.5 0.0 2.8e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase III mCpol PF18182.1 AJZ75849.1 - 1.1e-05 25.7 0.6 0.0021 18.4 0.1 2.2 2 0 0 2 2 2 2 minimal CRISPR polymerase domain Guanylate_cyc PF00211.20 AJZ75849.1 - 0.00013 21.7 1.0 0.0002 21.0 0.3 1.8 2 1 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain GGDEF_2 PF17853.1 AJZ75849.1 - 0.003 17.8 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 1 GGDEF-like domain DMRL_synthase PF00885.19 AJZ75850.1 - 4.8e-30 104.2 0.2 5.5e-30 104.0 0.2 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Metallophos_3 PF14582.6 AJZ75850.1 - 0.054 12.8 0.1 0.1 11.9 0.1 1.4 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DHBP_synthase PF00926.19 AJZ75851.1 - 1.1e-59 201.1 0.0 1.3e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Nitroreductase PF00881.24 AJZ75852.1 - 1.6e-35 122.7 0.2 2.1e-35 122.3 0.2 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AJZ75852.1 - 9e-11 41.7 0.1 8.2e-05 22.3 0.5 3.0 2 1 1 3 3 3 3 Putative TM nitroreductase zf-U11-48K PF05253.12 AJZ75852.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger DUF4383 PF14325.6 AJZ75853.1 - 0.0078 16.5 2.0 0.012 15.9 2.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4383) ThrE_2 PF12821.7 AJZ75853.1 - 0.028 14.6 1.2 0.031 14.4 1.2 1.0 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE DUF3290 PF11694.8 AJZ75853.1 - 0.072 13.1 1.0 0.074 13.0 0.7 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3290) DUF2206 PF09971.9 AJZ75853.1 - 0.33 9.7 5.4 0.4 9.4 5.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF3040 PF11239.8 AJZ75853.1 - 1.9 8.8 4.7 1.2 9.5 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) UPF0154 PF03672.13 AJZ75853.1 - 5.5 7.1 5.2 0.84 9.7 0.6 2.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) YtpI PF14007.6 AJZ75853.1 - 8.6 6.6 9.2 0.47 10.6 1.2 2.3 1 1 1 2 2 2 0 YtpI-like protein HTH_20 PF12840.7 AJZ75854.1 - 4.7e-10 39.4 0.0 6.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AJZ75854.1 - 1.3e-06 28.1 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 AJZ75854.1 - 6.9e-06 25.9 0.2 1e-05 25.3 0.2 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 AJZ75854.1 - 1.2e-05 25.1 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AJZ75854.1 - 3.2e-05 23.4 0.6 6.4e-05 22.4 0.6 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AJZ75854.1 - 4.1e-05 23.5 1.3 6.2e-05 22.9 1.3 1.3 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 AJZ75854.1 - 0.0038 17.1 0.1 0.0068 16.3 0.1 1.4 1 0 0 1 1 1 1 MarR family FUR PF01475.19 AJZ75854.1 - 0.014 15.5 0.2 0.019 15.1 0.2 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family MarR PF01047.22 AJZ75854.1 - 0.016 15.1 0.4 0.029 14.3 0.4 1.4 1 0 0 1 1 1 0 MarR family DUF4423 PF14394.6 AJZ75854.1 - 0.067 12.9 0.1 0.072 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Mga PF05043.13 AJZ75854.1 - 0.085 13.4 0.1 0.13 12.9 0.1 1.3 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_23 PF13384.6 AJZ75854.1 - 0.1 12.5 0.5 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain fn3 PF00041.21 AJZ75855.1 - 1.4e-09 38.1 0.6 2.5e-09 37.4 0.6 1.4 1 0 0 1 1 1 1 Fibronectin type III domain V-ATPase_G_2 PF16999.5 AJZ75855.1 - 0.019 15.4 2.6 0.019 15.4 2.6 2.2 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit AglB_L1 PF18079.1 AJZ75855.1 - 0.065 13.5 0.3 0.11 12.8 0.3 1.3 1 0 0 1 1 1 0 Archaeal glycosylation protein B long peripheral domain MADF_DNA_bdg PF10545.9 AJZ75855.1 - 0.25 11.7 15.9 1.8 8.9 3.8 2.7 1 1 2 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RRF PF01765.19 AJZ75855.1 - 0.29 11.1 24.3 0.46 10.4 9.1 2.3 2 0 0 2 2 2 0 Ribosome recycling factor TetR_C_13 PF16925.5 AJZ75855.1 - 0.32 10.9 2.1 1.3 8.9 0.2 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PMEI PF04043.15 AJZ75855.1 - 0.46 10.8 6.4 1.1 9.6 6.0 1.9 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DPM3 PF08285.11 AJZ75855.1 - 0.54 10.5 5.5 1.7 8.9 0.4 2.6 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3348 PF11828.8 AJZ75855.1 - 1 9.0 5.0 0.34 10.6 1.2 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3348) YtxH PF12732.7 AJZ75855.1 - 1.3 9.6 20.0 3.4e+03 -1.3 20.0 3.6 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 AJZ75855.1 - 1.6 9.4 13.3 4.7 7.9 2.0 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) ELFV_dehydrog PF00208.21 AJZ75855.1 - 2 8.1 8.8 0.16 11.7 1.2 2.4 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAAA-beta PF15508.6 AJZ75855.1 - 2.4 8.5 5.4 61 4.0 0.3 3.4 2 1 1 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Tup_N PF08581.10 AJZ75855.1 - 7.7 6.9 17.3 5.6 7.3 5.1 2.8 2 1 0 2 2 2 0 Tup N-terminal PIN_8 PF18476.1 AJZ75855.1 - 7.8 6.3 20.6 1.8 8.3 7.6 2.2 1 1 1 2 2 2 0 PIN like domain DUF4423 PF14394.6 AJZ75856.1 - 0.00035 20.3 0.0 0.00082 19.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_45 PF14947.6 AJZ75856.1 - 0.0081 16.1 2.6 0.039 14.0 0.1 2.9 3 0 0 3 3 3 1 Winged helix-turn-helix HTH_5 PF01022.20 AJZ75856.1 - 0.013 15.4 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 AJZ75856.1 - 0.027 14.4 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AJZ75856.1 - 0.051 13.5 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 MarR family HTH_20 PF12840.7 AJZ75856.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AJZ75856.1 - 0.058 13.0 0.3 0.28 10.8 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF2250 PF10007.9 AJZ75856.1 - 0.85 9.8 3.5 30 4.8 0.3 3.1 2 2 2 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2250) B12-binding PF02310.19 AJZ75857.1 - 5.5e-13 49.0 0.0 8.1e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 AJZ75857.1 - 3.6e-09 36.9 0.0 6.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain FAD_binding_7 PF03441.14 AJZ75858.1 - 1.5e-74 249.8 1.7 2.7e-74 249.0 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 AJZ75858.1 - 3.7e-37 127.9 0.0 9.2e-37 126.6 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase Hemocyanin_N PF03722.14 AJZ75858.1 - 0.11 13.1 2.4 0.12 12.9 0.1 2.2 2 1 0 2 2 2 0 Hemocyanin, all-alpha domain Nitroreductase PF00881.24 AJZ75859.1 - 5.1e-24 85.2 0.5 2.1e-12 47.5 0.1 2.3 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 AJZ75859.1 - 2.3e-08 33.9 0.3 0.002 17.8 0.0 3.1 2 1 1 3 3 3 2 Putative TM nitroreductase DUF1411 PF07199.11 AJZ75859.1 - 0.18 11.5 2.3 0.15 11.7 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1411) Cys_rich_KTR PF14205.6 AJZ75861.1 - 0.013 15.3 0.8 0.023 14.5 0.8 1.5 1 0 0 1 1 1 0 Cysteine-rich KTR Methyltransf_11 PF08241.12 AJZ75863.1 - 1.7e-11 44.6 0.0 4.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJZ75863.1 - 7.9e-09 36.1 0.0 1.9e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJZ75863.1 - 1.1e-05 26.1 0.0 2.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJZ75863.1 - 1.3e-05 25.1 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AJZ75863.1 - 7.7e-05 22.3 0.0 0.00014 21.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 AJZ75863.1 - 0.00011 21.6 0.0 0.0003 20.2 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 AJZ75863.1 - 0.019 14.8 0.0 0.058 13.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Intg_mem_TP0381 PF09529.10 AJZ75864.1 - 0.0031 17.0 6.4 0.0031 17.0 6.4 2.7 2 1 1 3 3 3 1 Integral membrane protein (intg_mem_TP0381) BphX PF06139.12 AJZ75864.1 - 0.027 14.4 4.6 0.33 10.9 0.0 3.3 3 1 0 3 3 3 0 BphX-like BT1 PF03092.16 AJZ75865.1 - 0.022 13.0 0.1 0.027 12.7 0.1 1.1 1 0 0 1 1 1 0 BT1 family BatD PF13584.6 AJZ75865.1 - 0.089 11.6 1.7 0.22 10.3 0.1 1.9 2 0 0 2 2 2 0 Oxygen tolerance HpcH_HpaI PF03328.14 AJZ75866.1 - 5.8e-46 156.4 0.0 7e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AJZ75866.1 - 4e-17 62.4 0.0 2.5e-08 33.5 0.0 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF5063 PF16702.5 AJZ75866.1 - 0.0048 17.3 0.0 0.0076 16.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5063) Trehalose_PPase PF02358.16 AJZ75866.1 - 0.0065 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase ADH_zinc_N PF00107.26 AJZ75867.1 - 2.8e-26 92.0 0.1 4.8e-26 91.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AJZ75867.1 - 1.2e-23 83.0 0.3 2.1e-23 82.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 AJZ75867.1 - 9.2e-18 65.6 0.0 1.8e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.10 AJZ75867.1 - 0.14 12.3 0.2 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal dsDNA_bind PF01984.20 AJZ75868.1 - 4.3e-25 88.1 0.5 4.6e-25 88.1 0.5 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Ribosomal_S19e PF01090.19 AJZ75869.1 - 2e-47 160.4 0.0 2.2e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e GntR PF00392.21 AJZ75869.1 - 0.063 12.9 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 AJZ75869.1 - 0.13 12.2 0.2 0.25 11.3 0.2 1.4 1 0 0 1 1 1 0 HTH domain DUF2067 PF09840.9 AJZ75869.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Rpr2 PF04032.16 AJZ75870.1 - 8e-13 48.5 0.4 9.5e-13 48.2 0.4 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain C1_1 PF00130.22 AJZ75870.1 - 0.017 15.0 0.3 0.027 14.4 0.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF572 PF04502.13 AJZ75870.1 - 0.028 14.0 0.7 0.031 13.9 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Sigma54_DBD PF04552.13 AJZ75870.1 - 0.068 12.9 0.1 0.098 12.4 0.1 1.3 1 0 0 1 1 1 0 Sigma-54, DNA binding domain HNH_5 PF14279.6 AJZ75870.1 - 0.24 11.3 2.5 2.5 8.1 2.6 2.1 1 1 0 1 1 1 0 HNH endonuclease Sua5_yciO_yrdC PF01300.18 AJZ75871.1 - 2e-58 196.8 0.1 3e-58 196.3 0.1 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 AJZ75871.1 - 1.9e-32 112.7 0.0 3e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding HTH_AsnC-type PF13404.6 AJZ75872.1 - 8.9e-14 51.0 0.2 1.4e-13 50.4 0.2 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AJZ75872.1 - 1e-11 44.2 0.4 1.6e-11 43.6 0.4 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AJZ75872.1 - 7.6e-05 22.5 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Arc_trans_TRASH PF08394.10 AJZ75872.1 - 0.00032 21.0 3.3 0.00052 20.3 3.3 1.4 1 0 0 1 1 1 1 Archaeal TRASH domain HTH_5 PF01022.20 AJZ75872.1 - 0.00047 20.0 0.0 0.00097 19.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.6 AJZ75872.1 - 0.00089 18.6 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 ATPase-cat_bd PF12156.8 AJZ75872.1 - 0.001 19.8 0.9 0.0026 18.4 0.6 1.8 2 0 0 2 2 2 1 Putative metal-binding domain of cation transport ATPase DUF2250 PF10007.9 AJZ75872.1 - 0.0016 18.5 0.3 0.031 14.4 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_9 PF08221.11 AJZ75872.1 - 0.0018 18.3 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain MarR_2 PF12802.7 AJZ75872.1 - 0.0091 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 MarR family DUF4423 PF14394.6 AJZ75872.1 - 0.027 14.2 0.0 0.043 13.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_23 PF13384.6 AJZ75872.1 - 0.031 14.1 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DUF1272 PF06906.11 AJZ75872.1 - 0.035 14.2 1.5 0.055 13.6 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Sigma70_r4_2 PF08281.12 AJZ75872.1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HLH PF00010.26 AJZ75872.1 - 0.075 13.0 0.3 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain HTH_38 PF13936.6 AJZ75872.1 - 0.077 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain FeoC PF09012.10 AJZ75872.1 - 0.11 12.6 4.7 0.33 11.0 0.0 2.9 3 1 1 4 4 4 0 FeoC like transcriptional regulator HTH_IclR PF09339.10 AJZ75872.1 - 0.19 11.5 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain Ribosomal_L44 PF00935.19 AJZ75872.1 - 0.28 11.7 0.3 0.28 11.7 0.3 2.2 3 0 0 3 3 3 0 Ribosomal protein L44 Ferritin PF00210.24 AJZ75873.1 - 6.7e-34 116.8 0.4 7.4e-34 116.7 0.4 1.0 1 0 0 1 1 1 1 Ferritin-like domain FAS_I_H PF18314.1 AJZ75873.1 - 0.0011 18.6 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Osmo_CC PF08946.10 AJZ75873.1 - 0.02 15.1 0.3 0.044 14.0 0.0 1.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF885 PF05960.11 AJZ75873.1 - 0.06 13.0 0.2 0.071 12.7 0.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) ParD_antitoxin PF03693.14 AJZ75873.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Cation_efflux PF01545.21 AJZ75874.1 - 1.9e-43 148.5 20.5 2.3e-43 148.2 20.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AJZ75874.1 - 0.021 15.0 2.0 0.034 14.3 2.0 1.3 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter DUF3845 PF12956.7 AJZ75875.1 - 0.041 13.3 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure HTH_5 PF01022.20 AJZ75876.1 - 3.7e-16 58.7 0.1 5.8e-08 32.5 0.1 2.3 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AJZ75876.1 - 2.4e-10 39.8 0.0 0.00077 19.0 0.0 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AJZ75876.1 - 2.4e-07 30.5 0.0 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 AJZ75876.1 - 1.1e-06 28.5 0.2 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 2 MarR family HTH_34 PF13601.6 AJZ75876.1 - 7.8e-05 22.8 0.3 0.084 13.1 0.0 2.3 2 0 0 2 2 2 2 Winged helix DNA-binding domain MarR_2 PF12802.7 AJZ75876.1 - 0.00039 20.3 0.0 0.0058 16.5 0.0 2.1 2 0 0 2 2 2 1 MarR family Rrf2 PF02082.20 AJZ75876.1 - 0.0015 18.9 0.0 2 8.8 0.0 2.2 2 0 0 2 2 2 2 Transcriptional regulator HTH_45 PF14947.6 AJZ75876.1 - 0.002 18.0 1.3 0.0083 16.1 0.2 2.1 2 1 0 2 2 2 1 Winged helix-turn-helix HTH_IclR PF09339.10 AJZ75876.1 - 0.0022 17.8 0.0 0.055 13.3 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain DprA_WH PF17782.1 AJZ75876.1 - 0.036 14.2 0.0 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 DprA winged helix domain XK-related PF09815.9 AJZ75877.1 - 0.0067 15.5 4.6 0.0076 15.3 4.6 1.2 1 0 0 1 1 1 1 XK-related protein EVC2_like PF12297.8 AJZ75877.1 - 1.1 7.9 2.2 1.5 7.4 2.2 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF1272 PF06906.11 AJZ75881.1 - 0.13 12.4 8.9 1 9.5 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) DUF35_N PF12172.8 AJZ75881.1 - 2.3 8.2 10.4 38 4.3 4.3 2.7 1 1 1 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PolC_DP2 PF03833.13 AJZ75881.1 - 3.4 5.4 5.9 3.4 5.4 5.9 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-ribbon_3 PF13248.6 AJZ75881.1 - 6.3 6.4 12.8 7.8 6.1 0.5 2.6 1 1 1 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 AJZ75881.1 - 7.5 6.8 11.9 0.41 10.8 5.7 1.8 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-TFIIB PF13453.6 AJZ75881.1 - 8 5.9 12.0 17 4.8 1.7 3.1 2 1 1 3 3 3 0 Transcription factor zinc-finger HTH_24 PF13412.6 AJZ75883.1 - 1.6e-15 56.4 3.9 7e-07 28.7 0.0 2.9 2 1 1 3 3 3 2 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AJZ75883.1 - 2.2e-11 43.5 0.0 5.6e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 MarR family HTH_5 PF01022.20 AJZ75883.1 - 5.8e-10 38.9 0.1 0.00021 21.1 0.1 2.4 2 1 0 2 2 2 2 Bacterial regulatory protein, arsR family MarR PF01047.22 AJZ75883.1 - 1.2e-08 34.8 0.2 0.0062 16.4 0.1 2.2 2 0 0 2 2 2 2 MarR family HTH_20 PF12840.7 AJZ75883.1 - 1.4e-08 34.7 0.0 0.00053 20.0 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain FaeA PF04703.12 AJZ75883.1 - 1.4e-07 31.8 0.0 0.0067 16.8 0.0 2.4 2 0 0 2 2 2 2 FaeA-like protein HTH_34 PF13601.6 AJZ75883.1 - 1.9e-05 24.8 0.0 0.00021 21.4 0.0 2.1 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AJZ75883.1 - 3.2e-05 23.6 0.0 0.03 14.1 0.0 2.3 2 0 0 2 2 2 2 IclR helix-turn-helix domain DUF4423 PF14394.6 AJZ75883.1 - 4e-05 23.4 0.0 0.0092 15.7 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4423) TrmB PF01978.19 AJZ75883.1 - 0.00017 21.4 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 AJZ75883.1 - 0.0011 18.9 0.1 0.039 13.9 0.0 2.6 2 1 1 3 3 3 1 HTH domain HTH_45 PF14947.6 AJZ75883.1 - 0.003 17.5 0.5 0.26 11.3 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix LexA_DNA_bind PF01726.16 AJZ75883.1 - 0.0037 17.0 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 LexA DNA binding domain HTH_36 PF13730.6 AJZ75883.1 - 0.0063 16.4 0.0 0.44 10.5 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain GerE PF00196.19 AJZ75883.1 - 0.01 15.4 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Mrr_N PF14338.6 AJZ75883.1 - 0.01 15.9 0.1 7.8 6.7 0.0 2.5 2 1 1 3 3 3 0 Mrr N-terminal domain RPA_C PF08784.11 AJZ75883.1 - 0.012 16.3 0.8 0.026 15.2 0.1 1.8 2 1 0 2 2 2 0 Replication protein A C terminal HTH_41 PF14502.6 AJZ75883.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain RP-C PF03428.13 AJZ75883.1 - 0.028 14.1 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Replication protein C N-terminal domain Mga PF05043.13 AJZ75883.1 - 0.033 14.8 0.5 9.5 6.9 0.0 2.6 2 1 0 2 2 2 0 Mga helix-turn-helix domain HTH_27 PF13463.6 AJZ75883.1 - 0.039 14.5 0.0 8.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF2250 PF10007.9 AJZ75883.1 - 0.041 14.0 0.4 8.1 6.6 0.0 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) GntR PF00392.21 AJZ75883.1 - 0.09 12.4 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 AJZ75883.1 - 0.1 12.4 0.6 0.25 11.1 0.0 2.0 3 0 0 3 3 2 0 DeoR-like helix-turn-helix domain Penicillinase_R PF03965.16 AJZ75883.1 - 0.1 12.9 0.0 2.8 8.3 0.0 2.2 1 1 1 2 2 2 0 Penicillinase repressor Rrf2 PF02082.20 AJZ75883.1 - 0.16 12.4 0.0 15 6.0 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator Piezo_RRas_bdg PF12166.8 AJZ75884.1 - 0.0053 16.1 0.0 0.0058 16.0 0.0 1.0 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain Usp PF00582.26 AJZ75885.1 - 3.9e-31 108.4 0.0 4.8e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family L-fibroin PF05849.11 AJZ75885.1 - 0.0017 17.7 0.1 0.0019 17.5 0.1 1.1 1 0 0 1 1 1 1 Fibroin light chain (L-fibroin) DNA_photolyase PF00875.18 AJZ75885.1 - 0.0018 18.3 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase Pilin_N PF07790.11 AJZ75886.1 - 0.1 13.5 0.9 0.14 13.1 0.6 1.5 1 1 0 1 1 1 0 Archaeal Type IV pilin, N-terminal MFS_1 PF07690.16 AJZ75887.1 - 5.2e-38 130.9 30.5 5.5e-24 84.7 8.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AJZ75887.1 - 1.3e-07 30.6 19.6 7.3e-06 24.8 12.9 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 AJZ75887.1 - 5.2e-07 28.9 13.9 0.0032 16.4 11.4 2.1 1 1 0 2 2 2 2 MFS_1 like family LacY_symp PF01306.19 AJZ75887.1 - 1.9e-06 26.9 2.6 1.9e-06 26.9 2.6 2.4 2 1 0 2 2 2 1 LacY proton/sugar symporter MFS_3 PF05977.13 AJZ75887.1 - 0.0017 16.8 6.3 0.0037 15.7 6.3 1.6 1 1 0 1 1 1 1 Transmembrane secretion effector DUF4330 PF14221.6 AJZ75888.1 - 0.012 15.8 0.3 0.02 15.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) EamA PF00892.20 AJZ75889.1 - 2.9e-41 140.9 38.3 9.4e-21 74.4 13.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AJZ75889.1 - 0.00018 21.0 20.7 0.00032 20.1 20.7 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family TMEM234 PF10639.9 AJZ75889.1 - 0.0008 19.4 15.3 0.013 15.5 2.2 2.8 2 1 0 2 2 2 2 Putative transmembrane family 234 CRT-like PF08627.10 AJZ75889.1 - 0.014 14.4 17.4 0.13 11.2 9.4 2.2 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Multi_Drug_Res PF00893.19 AJZ75889.1 - 1.2 9.8 17.8 0.13 13.0 3.2 3.3 2 2 1 3 3 3 0 Small Multidrug Resistance protein EMG1 PF03587.14 AJZ75890.1 - 3.6e-43 147.5 0.0 4.1e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyco_transf_4 PF13439.6 AJZ75890.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_hydro_42 PF02449.15 AJZ75891.1 - 0.0016 17.8 0.4 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 AJZ75891.1 - 0.0054 16.4 1.4 0.0095 15.6 1.4 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Ribonuc_red_lgC PF02867.15 AJZ75892.1 - 6.8e-182 605.6 0.0 9.8e-182 605.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 AJZ75892.1 - 8.4e-30 102.6 0.2 2e-29 101.4 0.2 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 AJZ75892.1 - 2.7e-21 75.9 0.1 8.4e-21 74.3 0.1 1.9 1 0 0 1 1 1 1 ATP cone domain OB_aCoA_assoc PF01796.17 AJZ75893.1 - 5.6e-09 35.9 0.1 7.4e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 AJZ75893.1 - 0.00056 19.7 0.1 0.0008 19.2 0.1 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 AJZ75893.1 - 0.0027 17.4 3.2 0.0044 16.7 3.2 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AJZ75893.1 - 0.019 15.0 0.3 0.027 14.5 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon TackOD1 PF18551.1 AJZ75893.1 - 0.028 14.1 0.4 0.035 13.8 0.4 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Thioredoxin_3 PF13192.6 AJZ75893.1 - 0.065 13.3 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin domain CpXC PF14353.6 AJZ75893.1 - 0.089 12.8 0.8 1.5 8.9 0.1 2.1 1 1 1 2 2 2 0 CpXC protein Thiolase_N PF00108.23 AJZ75894.1 - 8.4e-22 77.8 0.0 2e-21 76.5 0.0 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AJZ75894.1 - 2.3e-12 46.6 1.7 1.9e-10 40.5 0.1 3.4 2 2 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AJZ75894.1 - 7.8e-05 22.4 0.1 0.024 14.2 0.1 3.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AJZ75894.1 - 0.0032 17.3 0.1 1.1 9.1 0.1 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 AJZ75894.1 - 0.05 13.6 1.0 1.1 9.3 0.0 2.9 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain zf-C4_Topoisom PF01396.19 AJZ75895.1 - 1.4e-06 28.0 11.2 2.6e-06 27.1 2.7 2.6 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_recom PF13408.6 AJZ75895.1 - 0.018 15.6 2.2 0.018 15.6 2.2 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L29 PF00831.23 AJZ75895.1 - 0.23 11.5 3.4 0.37 10.8 3.4 1.3 1 0 0 1 1 1 0 Ribosomal L29 protein Ogr_Delta PF04606.12 AJZ75895.1 - 1.5 8.8 11.0 1.6 8.8 1.6 3.1 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.7 AJZ75895.1 - 2.1 8.4 8.1 0.3 11.1 0.7 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain CN_hydrolase PF00795.22 AJZ75896.1 - 3e-54 184.1 0.0 3.4e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Flavoprotein PF02441.19 AJZ75896.1 - 0.034 13.9 0.1 0.49 10.1 0.0 2.1 1 1 1 2 2 2 0 Flavoprotein Sigma_reg_C PF13791.6 AJZ75896.1 - 0.081 13.1 0.8 0.16 12.1 0.8 1.5 1 0 0 1 1 1 0 Sigma factor regulator C-terminal DNA_pol_D_N PF18018.1 AJZ75896.1 - 0.085 13.0 0.2 0.18 11.9 0.2 1.7 1 1 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain Tautomerase PF01361.21 AJZ75897.1 - 8.2e-16 57.7 0.1 8.7e-16 57.6 0.1 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.6 AJZ75897.1 - 8.9e-08 32.1 0.0 9.3e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_3 PF14832.6 AJZ75897.1 - 0.058 13.6 0.0 0.058 13.6 0.0 1.0 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme Matrix PF00661.21 AJZ75897.1 - 0.09 11.5 0.0 0.09 11.5 0.0 1.0 1 0 0 1 1 1 0 Viral matrix protein Rhomboid PF01694.22 AJZ75898.1 - 6.6e-34 117.1 20.3 1.2e-33 116.2 20.3 1.3 1 0 0 1 1 1 1 Rhomboid family Dioxygenase_N PF04444.14 AJZ75899.1 - 0.027 14.3 0.0 4 7.4 0.0 2.3 2 0 0 2 2 2 0 Catechol dioxygenase N terminus DUF3987 PF13148.6 AJZ75899.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Copper-bind PF00127.20 AJZ75901.1 - 9.2e-06 26.0 0.5 2.9e-05 24.4 0.0 2.0 2 1 1 3 3 3 1 Copper binding proteins, plastocyanin/azurin family ZirS_C PF16583.5 AJZ75901.1 - 0.00025 20.7 0.1 0.00042 19.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-regulated secreted antivirulence protein C-terminal domain Invasin_D3 PF09134.10 AJZ75901.1 - 0.0037 17.5 0.2 0.008 16.5 0.2 1.6 1 0 0 1 1 1 1 Invasin, domain 3 MG4 PF17789.1 AJZ75901.1 - 0.0042 17.2 0.1 0.01 16.0 0.1 1.6 1 0 0 1 1 1 1 Macroglobulin domain MG4 Cupredoxin_1 PF13473.6 AJZ75901.1 - 0.014 15.5 0.0 0.038 14.1 0.0 1.8 1 0 0 1 1 1 0 Cupredoxin-like domain Big_1 PF02369.16 AJZ75901.1 - 0.015 15.3 1.2 0.015 15.3 1.2 2.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) YtkA PF13115.6 AJZ75901.1 - 0.059 14.0 0.4 0.14 12.8 0.4 1.7 1 0 0 1 1 1 0 YtkA-like DUF2207 PF09972.9 AJZ75901.1 - 0.16 10.7 0.0 0.29 9.9 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF824 PF05688.11 AJZ75901.1 - 0.21 11.5 0.4 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) CopD PF05425.13 AJZ75903.1 - 7.5e-18 64.9 15.2 4.8e-17 62.3 2.3 2.7 2 0 0 2 2 2 2 Copper resistance protein D CopC PF04234.12 AJZ75903.1 - 9.7e-12 45.8 0.0 3.3e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 CopC domain SGL PF08450.12 AJZ75903.1 - 4.6e-10 39.5 0.1 0.00034 20.3 0.0 4.7 1 1 3 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 AJZ75903.1 - 7.5e-08 31.7 7.6 2.1 8.8 0.0 7.8 9 0 0 9 9 9 3 Two component regulator propeller YtkA PF13115.6 AJZ75903.1 - 3.8e-05 24.2 0.0 0.00014 22.4 0.0 1.9 2 0 0 2 2 2 1 YtkA-like Y_Y_Y PF07495.13 AJZ75903.1 - 0.0084 16.0 3.1 0.024 14.6 0.0 3.0 3 0 0 3 3 3 1 Y_Y_Y domain Wzt_C PF14524.6 AJZ75903.1 - 0.022 14.8 0.1 0.074 13.1 0.1 1.9 1 0 0 1 1 1 0 Wzt C-terminal domain PPC PF04151.15 AJZ75903.1 - 0.027 15.5 3.6 0.085 14.0 1.9 2.6 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain FBA_3 PF08268.12 AJZ75903.1 - 0.035 14.1 0.1 10 6.1 0.0 3.1 2 1 1 3 3 3 0 F-box associated domain DUF4149 PF13664.6 AJZ75903.1 - 4.3 7.7 16.2 0.14 12.5 1.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) DUF812 PF05667.11 AJZ75904.1 - 2.4e-06 26.7 80.7 0.0016 17.4 24.9 3.2 1 1 1 3 3 3 3 Protein of unknown function (DUF812) Filament PF00038.21 AJZ75904.1 - 0.00051 19.7 70.4 2.4 7.7 33.6 4.0 1 1 2 3 3 3 2 Intermediate filament protein CALCOCO1 PF07888.11 AJZ75904.1 - 0.0017 17.3 69.8 0.0047 15.9 4.7 3.2 1 1 2 3 3 3 2 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2353 PF09789.9 AJZ75904.1 - 0.017 14.5 62.7 0.61 9.4 33.2 3.7 2 1 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) PspA_IM30 PF04012.12 AJZ75904.1 - 0.042 13.4 0.1 0.042 13.4 0.1 5.0 2 1 0 3 3 3 0 PspA/IM30 family TPR_MLP1_2 PF07926.12 AJZ75904.1 - 0.052 13.6 84.1 0.051 13.6 31.5 6.4 3 1 4 7 7 7 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 AJZ75904.1 - 0.059 13.6 0.4 0.059 13.6 0.4 7.7 7 2 2 9 9 7 0 Homeobox associated leucine zipper DUF1664 PF07889.12 AJZ75904.1 - 0.083 12.9 48.1 1.3 9.1 0.9 6.1 3 1 3 6 6 6 0 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 AJZ75904.1 - 0.12 12.2 81.4 0.034 14.0 14.5 5.1 2 2 3 5 5 5 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 AJZ75904.1 - 0.13 11.1 88.3 0.18 10.6 28.1 5.2 2 1 4 6 6 6 0 Spc7 kinetochore protein COG2 PF06148.11 AJZ75904.1 - 0.14 12.2 43.2 0.33 11.0 0.7 6.0 3 1 3 7 7 7 0 COG (conserved oligomeric Golgi) complex component, COG2 EzrA PF06160.12 AJZ75904.1 - 0.17 10.0 75.2 0.017 13.4 3.3 4.7 2 1 1 4 4 4 0 Septation ring formation regulator, EzrA Seryl_tRNA_N PF02403.22 AJZ75904.1 - 0.18 12.1 75.0 0.035 14.3 12.1 6.3 3 1 2 6 6 6 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 AJZ75904.1 - 0.25 11.9 95.5 0.29 11.6 16.4 5.3 1 1 2 4 4 4 0 Apg6 coiled-coil region FPP PF05911.11 AJZ75904.1 - 0.26 9.4 77.2 0.092 10.9 44.0 3.0 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil Laminin_II PF06009.12 AJZ75904.1 - 0.5 10.4 50.7 1.5 8.8 0.6 5.8 3 1 4 7 7 7 0 Laminin Domain II Uso1_p115_C PF04871.13 AJZ75904.1 - 0.56 10.6 88.2 0.25 11.7 13.2 5.2 4 1 1 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region Golgin_A5 PF09787.9 AJZ75904.1 - 1.1 8.7 80.2 0.071 12.6 5.6 4.8 2 1 3 5 5 5 0 Golgin subfamily A member 5 MCC-bdg_PDZ PF10506.9 AJZ75904.1 - 1.6 8.8 23.5 0.49 10.5 0.3 4.3 4 1 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome GAS PF13851.6 AJZ75904.1 - 3 7.1 89.7 1.3 8.3 26.6 6.1 2 1 4 6 6 6 0 Growth-arrest specific micro-tubule binding DUF4472 PF14739.6 AJZ75904.1 - 3.1 8.6 67.5 0.04 14.6 8.1 5.6 3 1 2 5 5 5 0 Domain of unknown function (DUF4472) Tropomyosin_1 PF12718.7 AJZ75904.1 - 3.3 7.9 88.5 0.17 12.1 18.9 5.8 3 1 3 6 6 6 0 Tropomyosin like ADIP PF11559.8 AJZ75904.1 - 5.5 7.1 71.5 0.31 11.1 14.8 5.7 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding KELK PF15796.5 AJZ75904.1 - 8.4 6.9 84.4 0.64 10.5 5.0 7.5 2 1 4 7 7 7 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ABC_tran PF00005.27 AJZ75905.1 - 3e-27 95.8 0.0 7.4e-27 94.5 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AJZ75905.1 - 2.5e-16 60.4 0.2 3.7e-08 33.5 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AJZ75905.1 - 1.7e-05 25.4 5.8 0.00016 22.3 5.8 2.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AJZ75905.1 - 6.2e-05 22.5 1.2 0.013 14.9 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 AJZ75905.1 - 0.00032 20.4 0.3 0.00073 19.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AJZ75905.1 - 0.0013 19.2 0.8 0.1 13.1 0.8 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AJZ75905.1 - 0.0034 17.1 0.1 0.0076 16.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 AJZ75905.1 - 0.011 15.9 0.1 0.26 11.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AJZ75905.1 - 0.015 14.5 1.2 0.085 12.0 0.6 2.2 1 1 0 1 1 1 0 NB-ARC domain TniB PF05621.11 AJZ75905.1 - 0.028 13.8 0.3 0.41 10.0 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Septin PF00735.18 AJZ75905.1 - 0.031 13.5 1.2 15 4.7 0.0 3.0 3 0 0 3 3 3 0 Septin MMR_HSR1 PF01926.23 AJZ75905.1 - 0.058 13.5 0.4 0.16 12.1 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 AJZ75905.1 - 0.09 12.4 0.2 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 AJZ75905.1 - 0.09 12.7 1.2 0.48 10.3 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase AAA_14 PF13173.6 AJZ75905.1 - 0.11 12.6 0.6 7.9 6.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AJZ75905.1 - 0.13 12.5 0.2 0.35 11.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AJZ75905.1 - 0.25 11.0 5.0 0.38 10.4 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain NikR_C PF08753.11 AJZ75906.1 - 9.6e-12 44.9 1.6 1.4e-11 44.3 1.6 1.3 1 0 0 1 1 1 1 NikR C terminal nickel binding domain RHH_1 PF01402.21 AJZ75906.1 - 6.4e-07 29.1 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family VapB_antitoxin PF09957.9 AJZ75906.1 - 0.0003 20.7 0.1 0.00065 19.6 0.1 1.6 1 1 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB Arch_flagellin PF01917.16 AJZ75907.1 - 0.043 14.0 0.1 0.043 14.0 0.1 2.4 2 2 0 2 2 2 0 Archaebacterial flagellin Glyco_hydro_5_C PF18564.1 AJZ75907.1 - 1.4 9.5 3.7 1.7 9.3 0.2 2.9 4 1 0 4 4 4 0 Glycoside hydrolase family 5 C-terminal domain CheC PF04509.12 AJZ75908.1 - 0.00083 19.2 0.3 0.0019 18.1 0.3 1.6 1 0 0 1 1 1 1 CheC-like family CheX PF13690.6 AJZ75908.1 - 0.014 15.5 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX Response_reg PF00072.24 AJZ75909.1 - 1e-26 93.3 1.6 1.1e-26 93.1 1.6 1.0 1 0 0 1 1 1 1 Response regulator receiver domain TadZ_N PF16968.5 AJZ75909.1 - 0.062 13.0 0.1 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Pilus assembly protein TadZ N-terminal CheW PF01584.19 AJZ75910.1 - 3.8e-36 123.8 2.1 4.4e-36 123.6 2.1 1.1 1 0 0 1 1 1 1 CheW-like domain CheR PF01739.18 AJZ75911.1 - 1.4e-53 181.3 0.0 1.8e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.6 AJZ75911.1 - 2e-09 37.4 0.0 0.00015 21.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 AJZ75911.1 - 9.7e-07 29.4 0.0 0.00027 21.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJZ75911.1 - 4.7e-06 26.5 0.0 7.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR_N PF03705.15 AJZ75911.1 - 8.4e-06 25.4 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.12 AJZ75911.1 - 1.5e-05 25.6 0.1 0.00014 22.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJZ75911.1 - 5.9e-05 23.6 0.0 0.0013 19.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 AJZ75911.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Cobalamin_bind PF01122.19 AJZ75912.1 - 0.0098 14.8 0.4 0.013 14.4 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein DUF1730 PF08331.10 AJZ75912.1 - 0.059 13.3 0.1 0.17 11.8 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1730) TMEM252 PF15664.5 AJZ75912.1 - 0.073 12.8 0.1 0.077 12.7 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 252 family T2SSF PF00482.23 AJZ75913.1 - 9e-06 25.7 0.1 9e-06 25.7 0.1 4.6 5 1 0 5 5 5 2 Type II secretion system (T2SS), protein F Spore_III_AB PF09548.10 AJZ75913.1 - 0.063 13.4 7.8 1.1 9.3 0.1 3.8 4 1 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) MACPF PF01823.19 AJZ75913.1 - 0.11 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 MAC/Perforin domain DUF1772 PF08592.11 AJZ75913.1 - 4 7.7 10.7 4.2 7.7 3.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF3278 PF11683.8 AJZ75913.1 - 4.7 7.3 13.7 0.3 11.2 1.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3278) T2SSE PF00437.20 AJZ75914.1 - 5.7e-45 153.5 0.0 7.7e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.29 AJZ75914.1 - 0.12 12.1 0.0 0.56 10.0 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 AJZ75914.1 - 0.16 12.5 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 AJZ75915.1 - 1.3e-15 57.4 0.0 1.4e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 KaiC DUF835 PF05763.12 AJZ75915.1 - 0.00028 20.6 0.2 0.0015 18.3 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF835) AAA_16 PF13191.6 AJZ75915.1 - 0.0041 17.5 0.0 0.0064 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AJZ75915.1 - 0.016 15.5 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AJZ75915.1 - 0.035 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 AJZ75915.1 - 0.046 13.6 0.1 0.097 12.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 AJZ75915.1 - 0.047 14.1 0.1 0.15 12.5 0.1 1.9 1 1 0 1 1 1 0 RNA helicase ETM PF17577.2 AJZ75915.1 - 0.057 14.0 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 ECORI-T site DUF2075 PF09848.9 AJZ75915.1 - 0.062 12.5 0.0 0.076 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ras PF00071.22 AJZ75915.1 - 0.071 12.7 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Ras family Helicase_RecD PF05127.14 AJZ75915.1 - 0.087 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Helicase Elong_Iki1 PF10483.9 AJZ75915.1 - 0.09 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 Roc PF08477.13 AJZ75915.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 AJZ75915.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Paramyx_P_V_C PF03210.13 AJZ75916.1 - 0.011 15.5 0.4 0.017 14.9 0.4 1.2 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Arch_flagellin PF01917.16 AJZ75917.1 - 3e-11 43.8 6.2 3.8e-11 43.5 6.2 1.1 1 0 0 1 1 1 1 Archaebacterial flagellin Sigma54_CBD PF04963.13 AJZ75918.1 - 0.024 14.5 0.2 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain Rep_fac_C PF08542.11 AJZ75918.1 - 0.082 13.3 0.2 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Replication factor C C-terminal domain Fib_alpha PF08702.10 AJZ75918.1 - 0.083 13.1 3.2 0.098 12.8 0.4 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Fusion_gly PF00523.18 AJZ75918.1 - 0.095 10.9 0.0 0.16 10.2 0.0 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 KxDL PF10241.9 AJZ75918.1 - 0.14 12.5 0.4 0.31 11.3 0.3 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein Arch_flagellin PF01917.16 AJZ75919.1 - 1.9e-23 83.5 7.4 2.4e-23 83.1 7.4 1.1 1 0 0 1 1 1 1 Archaebacterial flagellin Arch_flagellin PF01917.16 AJZ75920.1 - 4.5e-22 79.0 11.7 5.9e-22 78.6 11.7 1.2 1 0 0 1 1 1 1 Archaebacterial flagellin Arch_flagellin PF01917.16 AJZ75921.1 - 1.7e-20 73.9 7.2 2.1e-20 73.5 7.2 1.1 1 0 0 1 1 1 1 Archaebacterial flagellin FeoB_associated PF12669.7 AJZ75921.1 - 0.73 10.3 2.0 1.2 9.6 2.0 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Arch_flagellin PF01917.16 AJZ75922.1 - 3.5e-23 82.6 9.4 5.6e-23 81.9 9.4 1.3 1 1 0 1 1 1 1 Archaebacterial flagellin DUF5325 PF17259.2 AJZ75922.1 - 0.21 11.5 2.8 0.51 10.2 2.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5325) TPR_1 PF00515.28 AJZ75923.1 - 4.8e-155 497.8 62.7 6.1e-08 32.2 0.2 29.7 30 0 0 30 30 30 26 Tetratricopeptide repeat TPR_2 PF07719.17 AJZ75923.1 - 9.5e-141 446.9 54.5 6.3e-06 25.9 0.1 30.8 30 1 1 31 31 31 23 Tetratricopeptide repeat TPR_8 PF13181.6 AJZ75923.1 - 1.4e-103 330.7 63.2 0.00017 21.5 0.1 30.7 30 1 1 31 31 31 20 Tetratricopeptide repeat TPR_17 PF13431.6 AJZ75923.1 - 8.6e-83 267.0 70.9 5.5e-05 23.3 0.0 28.5 29 0 0 29 29 29 18 Tetratricopeptide repeat TPR_16 PF13432.6 AJZ75923.1 - 6.9e-78 257.1 0.0 4e-06 27.4 0.1 17.4 10 5 7 19 19 19 16 Tetratricopeptide repeat TPR_11 PF13414.6 AJZ75923.1 - 5.3e-76 250.1 58.6 1.4e-07 31.1 1.2 25.5 9 5 17 26 26 26 20 TPR repeat TPR_19 PF14559.6 AJZ75923.1 - 2e-73 242.8 42.1 2.7e-06 27.8 0.1 19.1 5 2 14 21 21 21 19 Tetratricopeptide repeat TPR_14 PF13428.6 AJZ75923.1 - 3e-71 230.0 0.1 0.019 15.7 0.0 25.7 6 5 22 28 28 28 16 Tetratricopeptide repeat TPR_9 PF13371.6 AJZ75923.1 - 3.2e-71 235.4 0.0 1.2e-06 28.5 0.0 16.4 6 5 12 20 20 18 17 Tetratricopeptide repeat ANAPC3 PF12895.7 AJZ75923.1 - 2.8e-68 226.2 75.3 3.2e-09 36.9 0.1 15.4 2 1 13 16 16 16 15 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 AJZ75923.1 - 3.3e-67 222.7 57.5 2.5e-10 40.5 2.0 20.1 11 6 8 20 20 20 14 Tetratricopeptide repeat TPR_6 PF13174.6 AJZ75923.1 - 3.3e-59 193.7 13.2 0.00019 21.9 0.0 25.1 28 0 0 28 28 25 9 Tetratricopeptide repeat TPR_7 PF13176.6 AJZ75923.1 - 6.5e-52 169.8 37.4 0.012 15.6 0.1 25.4 24 3 2 26 26 25 11 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJZ75923.1 - 2.1e-38 130.1 58.4 0.0016 18.4 0.1 24.4 11 8 14 26 26 26 9 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 AJZ75923.1 - 1.1e-24 85.5 18.3 0.12 12.3 0.0 19.9 25 0 0 25 25 21 3 Tetratricopeptide repeat SRP_TPR_like PF17004.5 AJZ75923.1 - 8.3e-20 71.0 42.6 0.001 19.0 0.2 12.4 3 3 8 12 12 12 7 Putative TPR-like repeat NARP1 PF12569.8 AJZ75923.1 - 1.5e-14 53.9 33.2 0.032 13.2 0.1 13.4 3 3 11 15 15 15 3 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 AJZ75923.1 - 6.9e-14 52.0 24.1 0.5 10.7 0.1 13.6 11 4 3 15 15 15 3 Tetratricopeptide repeat PknG_TPR PF16918.5 AJZ75923.1 - 1.4e-11 43.8 0.0 0.0049 15.6 0.0 5.8 3 3 2 5 5 5 3 Protein kinase G tetratricopeptide repeat DUF3856 PF12968.7 AJZ75923.1 - 1.6e-10 41.3 21.4 0.15 12.1 0.0 15.4 7 6 10 17 17 16 1 Domain of Unknown Function (DUF3856) BTAD PF03704.17 AJZ75923.1 - 1.6e-10 41.6 8.1 0.58 10.6 0.0 10.0 5 2 4 10 10 10 2 Bacterial transcriptional activator domain TPR_15 PF13429.6 AJZ75923.1 - 1.1e-08 34.6 18.0 0.32 10.2 0.1 8.8 2 2 3 7 7 7 3 Tetratricopeptide repeat Coatomer_E PF04733.14 AJZ75923.1 - 1.5e-08 34.4 30.7 0.84 9.0 0.4 9.9 3 2 7 11 11 11 2 Coatomer epsilon subunit PPR PF01535.20 AJZ75923.1 - 2.8e-07 30.3 10.4 5.1 7.6 0.0 11.5 16 0 0 16 16 7 0 PPR repeat Paf67 PF10255.9 AJZ75923.1 - 1.2e-06 27.8 16.8 0.053 12.5 0.6 8.8 3 3 4 8 8 8 1 RNA polymerase I-associated factor PAF67 NRBF2_MIT PF17169.4 AJZ75923.1 - 3e-05 24.1 13.7 1.9 8.8 0.1 9.6 10 1 1 11 11 10 1 MIT domain of nuclear receptor-binding factor 2 Alkyl_sulf_dimr PF14863.6 AJZ75923.1 - 8.4e-05 23.0 13.4 30 5.0 0.1 9.2 7 3 1 9 9 9 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 AJZ75923.1 - 0.00015 22.0 0.5 55 4.8 0.0 7.4 10 0 0 10 10 6 0 Tetratricopeptide repeat RPN6_N PF18055.1 AJZ75923.1 - 0.00088 19.6 10.7 2.5 8.5 0.1 7.1 8 0 0 8 8 5 1 26S proteasome regulatory subunit RPN6 N-terminal domain DUF2225 PF09986.9 AJZ75923.1 - 0.0018 18.1 10.0 0.084 12.6 0.1 5.5 3 1 2 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.18 AJZ75923.1 - 0.0039 17.2 40.7 0.39 10.8 0.0 15.3 14 4 3 18 18 16 1 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 AJZ75923.1 - 0.018 14.8 12.8 13 5.4 0.0 8.6 5 3 4 10 10 10 0 26S proteasome subunit RPN7 Peptidase_C8 PF03569.13 AJZ75923.1 - 0.023 14.2 0.7 0.33 10.5 0.1 3.0 3 0 0 3 3 3 0 Peptidase family C8 DUF1910 PF08928.10 AJZ75923.1 - 0.031 14.3 0.6 1.2 9.1 0.3 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) PaREP1 PF05942.11 AJZ75923.1 - 0.046 13.6 0.5 4.4 7.3 0.0 3.6 3 1 0 4 4 3 0 Archaeal PaREP1/PaREP8 family PEPcase PF00311.17 AJZ75923.1 - 0.19 9.8 0.6 0.9 7.5 0.3 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxylase YfiO PF13525.6 AJZ75923.1 - 1.1 9.0 17.8 3.7 7.2 0.4 5.9 6 1 0 6 6 5 0 Outer membrane lipoprotein Mad3_BUB1_I PF08311.12 AJZ75923.1 - 2.8 7.9 6.4 4.9 7.2 0.4 3.5 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 HTH_Bact PF18768.1 AJZ75923.1 - 4.7 6.9 17.4 1e+02 2.6 0.1 9.4 10 1 0 10 10 9 0 Helix-turn-helix bacterial domain TPR_1 PF00515.28 AJZ75924.1 - 7.4e-42 139.5 10.3 6.1e-07 29.0 0.0 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 AJZ75924.1 - 4.9e-38 126.2 10.5 1.4e-06 27.9 0.0 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 AJZ75924.1 - 3.5e-26 89.2 9.0 0.00056 19.9 0.0 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 AJZ75924.1 - 6.5e-25 87.5 0.1 7.5e-06 26.5 0.0 5.4 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 AJZ75924.1 - 1.4e-23 81.5 10.2 0.0086 16.4 0.2 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 AJZ75924.1 - 2.4e-21 74.6 0.1 0.0027 18.4 0.0 7.1 2 2 6 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 AJZ75924.1 - 2.8e-21 75.6 16.8 6.6e-09 35.9 0.8 5.1 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_6 PF13174.6 AJZ75924.1 - 5e-20 70.7 1.4 0.0088 16.6 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 AJZ75924.1 - 7.9e-20 70.3 7.8 0.0053 16.4 0.0 7.5 3 2 4 7 7 7 5 TPR repeat TPR_9 PF13371.6 AJZ75924.1 - 1.5e-16 60.3 0.0 0.00011 22.2 0.0 4.3 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 AJZ75924.1 - 6.9e-16 58.5 3.6 0.00013 22.4 0.1 4.7 1 1 4 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 AJZ75924.1 - 1.2e-15 56.2 5.7 0.12 12.5 0.0 7.4 8 0 0 8 8 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 AJZ75924.1 - 5.3e-14 52.2 12.6 1.8e-05 24.8 1.1 3.7 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 AJZ75924.1 - 2.2e-11 43.7 7.9 0.00026 21.0 0.1 4.8 4 1 1 5 5 5 3 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 AJZ75924.1 - 3.4e-09 36.3 1.4 0.026 14.4 0.1 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat NARP1 PF12569.8 AJZ75924.1 - 2.7e-07 29.9 1.3 0.0096 14.9 0.2 3.4 1 1 3 4 4 4 2 NMDA receptor-regulated protein 1 SRP_TPR_like PF17004.5 AJZ75924.1 - 1.7e-06 28.1 1.5 0.078 13.0 0.2 2.9 1 1 2 3 3 3 2 Putative TPR-like repeat BTAD PF03704.17 AJZ75924.1 - 7.1e-06 26.5 0.3 0.19 12.2 0.0 3.3 1 1 2 3 3 3 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 AJZ75924.1 - 1.4e-05 24.5 1.1 0.21 10.8 0.0 4.0 1 1 2 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 AJZ75924.1 - 3.2e-05 23.9 1.5 0.12 12.5 0.0 4.4 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 AJZ75924.1 - 9.5e-05 22.5 1.0 9.9 6.2 0.0 5.4 3 2 3 6 6 6 0 Domain of Unknown Function (DUF3856) PknG_TPR PF16918.5 AJZ75924.1 - 0.0016 17.3 0.0 0.3 9.8 0.0 2.6 1 1 2 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_5 PF12688.7 AJZ75924.1 - 0.0023 18.2 0.4 1.7 8.9 0.1 3.6 2 1 2 4 4 4 1 Tetratrico peptide repeat Paf67 PF10255.9 AJZ75924.1 - 0.0027 16.8 0.8 1.5 7.7 0.0 3.4 1 1 3 4 4 4 1 RNA polymerase I-associated factor PAF67 TPR_4 PF07721.14 AJZ75924.1 - 0.005 17.3 0.4 9.1 7.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 AJZ75924.1 - 0.024 14.1 0.2 0.5 9.7 0.0 2.5 1 1 2 3 3 3 0 Coatomer epsilon subunit RPN7 PF10602.9 AJZ75924.1 - 0.024 14.3 0.9 1.1 8.9 0.2 3.5 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 AJZ75924.1 - 0.055 13.8 4.1 3.4 8.0 0.0 4.1 2 2 3 5 5 5 0 Tetratricopeptide repeat DUF627 PF04781.12 AJZ75924.1 - 0.056 13.5 3.7 28 4.8 0.0 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF627) RPN6_N PF18055.1 AJZ75924.1 - 0.1 13.0 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_1 PF00515.28 AJZ75925.1 - 8e-108 348.3 29.2 2e-07 30.5 0.1 16.2 16 0 0 16 16 16 15 Tetratricopeptide repeat TPR_2 PF07719.17 AJZ75925.1 - 3.4e-95 304.7 22.4 7.6e-06 25.7 0.0 16.1 16 0 0 16 16 16 16 Tetratricopeptide repeat TPR_8 PF13181.6 AJZ75925.1 - 8.8e-74 237.7 26.2 2.7e-05 24.0 0.0 16.0 16 0 0 16 16 16 12 Tetratricopeptide repeat TPR_17 PF13431.6 AJZ75925.1 - 2.5e-63 206.0 32.2 0.00016 21.8 0.0 16.4 17 0 0 17 17 16 12 Tetratricopeptide repeat TPR_16 PF13432.6 AJZ75925.1 - 2.1e-60 201.1 0.0 1.3e-09 38.5 0.0 9.7 6 3 4 10 10 10 10 Tetratricopeptide repeat TPR_12 PF13424.6 AJZ75925.1 - 2.5e-54 181.5 24.3 3e-09 37.0 0.4 11.3 6 5 5 11 11 10 9 Tetratricopeptide repeat TPR_19 PF14559.6 AJZ75925.1 - 2.8e-54 181.5 7.9 1.6e-07 31.7 0.0 11.2 4 3 4 10 10 10 10 Tetratricopeptide repeat TPR_11 PF13414.6 AJZ75925.1 - 4.4e-54 179.9 33.7 2.9e-05 23.6 1.2 15.5 3 2 13 16 16 16 11 TPR repeat TPR_14 PF13428.6 AJZ75925.1 - 7.3e-47 154.0 0.0 0.0056 17.4 0.0 15.3 1 1 15 16 16 16 8 Tetratricopeptide repeat TPR_7 PF13176.6 AJZ75925.1 - 1e-41 137.9 12.2 0.0011 18.8 0.0 15.4 13 3 3 16 16 16 7 Tetratricopeptide repeat TPR_9 PF13371.6 AJZ75925.1 - 4.5e-40 135.7 0.0 4.7e-05 23.4 0.0 9.1 4 2 4 9 9 9 8 Tetratricopeptide repeat ANAPC3 PF12895.7 AJZ75925.1 - 1.4e-38 131.0 29.1 5.8e-08 32.9 2.3 7.4 1 1 8 9 9 9 9 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AJZ75925.1 - 3e-35 118.5 2.6 0.072 13.8 0.0 14.6 16 0 0 16 16 14 6 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJZ75925.1 - 4e-27 94.0 21.1 0.014 15.5 0.0 13.5 9 5 6 15 15 13 8 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 AJZ75925.1 - 5.7e-22 76.9 10.2 0.47 10.4 0.3 13.2 16 0 0 16 16 14 4 Tetratricopeptide repeat DUF3856 PF12968.7 AJZ75925.1 - 1.9e-16 60.5 0.3 3.5 7.7 0.0 11.3 2 1 6 10 10 10 1 Domain of Unknown Function (DUF3856) BTAD PF03704.17 AJZ75925.1 - 6.2e-15 55.9 0.0 0.41 11.1 0.0 7.4 2 2 5 7 7 7 3 Bacterial transcriptional activator domain NARP1 PF12569.8 AJZ75925.1 - 1.9e-13 50.2 5.7 0.05 12.5 0.1 7.9 1 1 6 9 9 9 4 NMDA receptor-regulated protein 1 SRP_TPR_like PF17004.5 AJZ75925.1 - 3.9e-12 46.2 10.4 0.0059 16.6 0.1 8.2 2 2 5 8 8 8 2 Putative TPR-like repeat TPR_20 PF14561.6 AJZ75925.1 - 6.3e-11 42.5 1.8 17 5.8 0.0 8.8 3 2 3 9 9 9 0 Tetratricopeptide repeat Coatomer_E PF04733.14 AJZ75925.1 - 2.7e-10 40.1 4.2 0.082 12.3 0.1 5.8 2 2 3 5 5 5 5 Coatomer epsilon subunit TPR_15 PF13429.6 AJZ75925.1 - 8e-10 38.4 1.2 0.44 9.7 0.0 6.6 1 1 3 6 6 6 3 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AJZ75925.1 - 4.4e-08 33.7 0.1 0.28 11.7 0.0 6.1 5 2 0 7 7 6 1 Alkyl sulfatase dimerisation TPR_5 PF12688.7 AJZ75925.1 - 1.1e-07 32.1 0.6 0.98 9.7 0.0 6.1 4 2 4 8 8 7 3 Tetratrico peptide repeat MIT PF04212.18 AJZ75925.1 - 5.5e-07 29.6 17.0 0.22 11.6 0.0 10.8 10 4 3 13 13 11 1 MIT (microtubule interacting and transport) domain PPR PF01535.20 AJZ75925.1 - 1.3e-06 28.3 5.5 23 5.5 0.0 9.1 11 0 0 11 11 8 0 PPR repeat TOM20_plant PF06552.12 AJZ75925.1 - 6.1e-06 26.1 3.0 1.4 8.7 0.1 7.4 3 2 4 7 7 7 1 Plant specific mitochondrial import receptor subunit TOM20 DUF627 PF04781.12 AJZ75925.1 - 0.00014 21.8 9.9 1.3 9.1 0.4 5.6 5 1 0 5 5 5 1 Protein of unknown function (DUF627) Sel1 PF08238.12 AJZ75925.1 - 0.00029 21.4 0.5 4.9 8.0 0.0 6.2 6 0 0 6 6 5 0 Sel1 repeat DUF5588 PF17826.1 AJZ75925.1 - 0.00078 18.4 1.9 1.1 8.1 0.3 3.9 2 2 2 4 4 4 2 Family of unknown function (DUF5588) NRBF2_MIT PF17169.4 AJZ75925.1 - 0.0027 17.9 4.8 19 5.6 0.1 6.0 4 1 1 5 5 5 0 MIT domain of nuclear receptor-binding factor 2 DUF5113 PF17140.4 AJZ75925.1 - 0.0029 17.4 16.9 7.1 6.4 0.2 8.3 5 3 3 9 9 9 0 Domain of unknown function (DUF5113) APP_E2 PF12925.7 AJZ75925.1 - 0.017 14.8 1.1 15 5.2 0.0 4.6 3 2 1 5 5 5 0 E2 domain of amyloid precursor protein TPR_4 PF07721.14 AJZ75925.1 - 0.019 15.6 0.0 18 6.3 0.0 5.4 8 0 0 8 8 3 0 Tetratricopeptide repeat PknG_TPR PF16918.5 AJZ75925.1 - 0.028 13.2 0.0 23 3.6 0.0 3.7 2 1 0 4 4 4 0 Protein kinase G tetratricopeptide repeat RIG-I_C PF18119.1 AJZ75925.1 - 0.074 13.1 0.6 1.4 8.9 0.0 3.0 2 1 1 3 3 2 0 RIG-I receptor C-terminal domain MAS20 PF02064.15 AJZ75925.1 - 0.092 12.8 0.3 92 3.1 0.0 4.6 3 2 2 5 5 5 0 MAS20 protein import receptor ANAPC5 PF12862.7 AJZ75925.1 - 0.19 11.8 10.2 3.1 7.9 0.2 5.7 4 2 2 6 6 6 0 Anaphase-promoting complex subunit 5 Big_1 PF02369.16 AJZ75926.1 - 0.0017 18.3 1.3 0.015 15.3 1.2 2.8 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) CarbopepD_reg_2 PF13715.6 AJZ75926.1 - 0.0069 16.4 2.3 0.74 9.9 0.2 3.5 3 0 0 3 3 3 2 CarboxypepD_reg-like domain CBS PF00571.28 AJZ75927.1 - 7.7e-06 26.3 2.2 0.66 10.5 0.0 3.6 3 0 0 3 3 3 3 CBS domain Cas_CXXC_CXXC PF09706.10 AJZ75927.1 - 0.001 19.3 0.5 0.54 10.5 0.1 2.7 2 1 0 2 2 2 2 CRISPR-associated protein (Cas_CXXC_CXXC) OTCace_N PF02729.21 AJZ75928.1 - 1.8e-37 128.6 0.0 2.7e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AJZ75928.1 - 1.8e-30 106.1 0.0 2.5e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF2149 PF09919.9 AJZ75928.1 - 0.048 13.9 0.0 8.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) PyrI PF01948.18 AJZ75929.1 - 4.1e-31 107.1 2.2 6.4e-31 106.5 2.2 1.3 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.15 AJZ75929.1 - 1e-14 54.2 3.1 1.7e-14 53.5 3.1 1.4 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF1936 PF09151.10 AJZ75929.1 - 0.014 15.3 0.2 0.03 14.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) zf-RING_7 PF02591.15 AJZ75929.1 - 0.1 12.8 0.1 0.56 10.4 0.1 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain Methyltransf_20 PF12147.8 AJZ75929.1 - 0.2 10.8 0.1 0.26 10.4 0.1 1.1 1 0 0 1 1 1 0 Putative methyltransferase ATP-synt_C PF00137.21 AJZ75930.1 - 1.3e-16 60.6 16.0 1.3e-16 60.6 16.0 1.7 2 0 0 2 2 2 1 ATP synthase subunit C ATP-synt_D PF01813.17 AJZ75931.1 - 3.9e-47 160.6 6.5 4.4e-47 160.4 6.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit D RNA_binding PF01877.17 AJZ75931.1 - 0.13 12.6 6.0 1 9.7 1.2 2.3 2 0 0 2 2 2 0 RNA binding DUF3746 PF12562.8 AJZ75931.1 - 0.13 12.2 0.4 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) ATP-synt_ab PF00006.25 AJZ75932.1 - 6.8e-69 231.8 0.0 9e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AJZ75932.1 - 2e-11 44.3 2.6 5.4e-11 42.8 1.5 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 AJZ75932.1 - 0.0003 20.9 0.3 0.001 19.1 0.3 2.0 1 0 0 1 1 1 1 HAS barrel domain ATP-synt_ab PF00006.25 AJZ75933.1 - 4.8e-94 314.0 0.0 6.4e-94 313.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 AJZ75933.1 - 2.7e-41 140.2 0.0 4.6e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 AJZ75933.1 - 3.9e-14 52.9 0.3 9.4e-14 51.7 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.6 AJZ75933.1 - 0.043 14.1 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_2 PF03668.15 AJZ75933.1 - 0.052 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop ATPase protein family DUF853 PF05872.12 AJZ75933.1 - 0.1 11.1 0.2 0.16 10.5 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RnfC_N PF13375.6 AJZ75933.1 - 0.12 12.3 0.2 14 5.7 0.0 2.5 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain vATP-synt_E PF01991.18 AJZ75934.1 - 2.2e-18 66.4 14.3 3.7e-17 62.4 14.1 2.4 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit KAsynt_C_assoc PF16197.5 AJZ75934.1 - 0.067 13.7 2.4 0.1 13.1 0.3 2.1 1 1 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension DUF4413 PF14372.6 AJZ75934.1 - 0.076 13.4 0.4 0.12 12.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Exonuc_VII_L PF02601.15 AJZ75934.1 - 0.098 12.2 4.9 0.12 11.9 4.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RHD3 PF05879.12 AJZ75934.1 - 0.11 10.7 7.5 0.12 10.5 7.5 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) SAC3 PF12209.8 AJZ75934.1 - 0.11 12.7 3.6 1.3 9.3 0.3 2.7 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain DUF4294 PF14127.6 AJZ75934.1 - 0.17 11.8 4.8 0.12 12.3 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4294) DnaG_DnaB_bind PF08278.11 AJZ75934.1 - 0.17 12.5 6.1 0.34 11.5 0.4 2.4 1 1 1 2 2 2 0 DNA primase DnaG DnaB-binding VraX PF17412.2 AJZ75934.1 - 0.21 11.3 1.1 0.51 10.0 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function Mis14 PF08641.12 AJZ75934.1 - 0.37 11.1 8.2 2.6 8.4 8.2 2.1 1 1 0 1 1 1 0 Kinetochore protein Mis14 like TRH PF05438.12 AJZ75934.1 - 1.2 8.8 5.6 0.57 9.9 2.4 1.9 1 1 1 2 2 2 0 Thyrotropin-releasing hormone (TRH) V_ATPase_I PF01496.19 AJZ75935.1 - 3.6e-24 84.8 10.0 8.2e-18 63.7 0.0 3.2 3 0 0 3 3 3 3 V-type ATPase 116kDa subunit family DUF624 PF04854.14 AJZ75935.1 - 0.026 14.6 0.5 0.096 12.8 0.5 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF624 Rhodanese PF00581.20 AJZ75936.1 - 8.4e-42 142.1 0.3 6.7e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Ammonium_transp PF00909.21 AJZ75937.1 - 1.1e-111 373.4 33.2 2.6e-111 372.1 33.2 1.6 1 1 0 1 1 1 1 Ammonium Transporter Family CDP-OH_P_transf PF01066.21 AJZ75937.1 - 0.28 12.0 0.1 0.28 12.0 0.1 3.7 3 1 0 3 3 3 0 CDP-alcohol phosphatidyltransferase vATP-synt_AC39 PF01992.16 AJZ75939.1 - 1.2e-55 189.4 8.4 1.4e-55 189.1 8.4 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit MerR-DNA-bind PF09278.11 AJZ75939.1 - 0.044 14.3 2.4 0.089 13.3 0.2 2.7 3 0 0 3 3 3 0 MerR, DNA binding DrrA_P4M PF14860.6 AJZ75939.1 - 0.17 11.7 4.0 1.3 8.9 0.1 2.9 3 0 0 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain Cas_Cas4 PF01930.17 AJZ75941.1 - 0.00032 20.8 0.9 0.00034 20.8 0.1 1.6 2 1 0 2 2 2 1 Domain of unknown function DUF83 TGT PF01702.18 AJZ75941.1 - 0.14 11.3 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase SlyX PF04102.12 AJZ75942.1 - 0.0031 18.1 10.1 0.051 14.2 0.9 3.3 3 0 0 3 3 3 2 SlyX Neugrin PF06413.11 AJZ75942.1 - 0.014 15.4 0.5 0.022 14.7 0.5 1.3 1 0 0 1 1 1 0 Neugrin DUF1664 PF07889.12 AJZ75942.1 - 0.016 15.3 4.8 0.91 9.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) APG17 PF04108.12 AJZ75942.1 - 0.02 14.0 7.5 0.029 13.5 7.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 SKA1 PF07160.12 AJZ75942.1 - 0.18 11.6 7.0 2.6 7.8 3.1 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF948 PF06103.11 AJZ75942.1 - 0.25 11.6 2.3 1.7 8.9 0.9 2.4 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ING PF12998.7 AJZ75942.1 - 0.27 11.8 7.1 0.55 10.9 0.5 2.3 1 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Fib_alpha PF08702.10 AJZ75942.1 - 0.51 10.5 6.1 96 3.1 5.8 2.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Rsa3 PF14615.6 AJZ75942.1 - 0.51 10.0 3.1 1.5 8.4 0.5 2.9 3 0 0 3 3 3 0 Ribosome-assembly protein 3 COMP PF11598.8 AJZ75942.1 - 2 9.0 6.8 1.6 9.2 1.8 3.0 2 1 1 3 3 3 0 Cartilage oligomeric matrix protein HD PF01966.22 AJZ75944.1 - 2.2e-16 60.2 0.2 5e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 AJZ75944.1 - 0.0094 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Cas_Csy4 PF09618.10 AJZ75944.1 - 0.049 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) HDOD PF08668.12 AJZ75944.1 - 0.072 12.6 0.1 0.17 11.3 0.1 1.6 1 1 1 2 2 2 0 HDOD domain Thymidylate_kin PF02223.17 AJZ75945.1 - 3.5e-34 118.1 0.1 3.9e-34 117.9 0.1 1.0 1 0 0 1 1 1 1 Thymidylate kinase HSP20 PF00011.21 AJZ75947.1 - 1.6e-12 47.5 0.4 2e-12 47.1 0.4 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AJZ75947.1 - 3.2e-10 39.4 0.1 7.5e-10 38.2 0.1 1.6 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Bunya_NS-S_2 PF03231.13 AJZ75947.1 - 0.0051 15.7 0.3 0.0051 15.7 0.3 1.1 1 0 0 1 1 1 1 Bunyavirus non-structural protein NS-S CS PF04969.16 AJZ75947.1 - 0.051 14.6 1.1 0.11 13.5 1.1 1.8 1 1 0 1 1 1 0 CS domain Apocytochr_F_N PF16639.5 AJZ75947.1 - 0.36 11.1 2.8 10 6.4 0.1 2.2 1 1 1 2 2 2 0 Apocytochrome F, N-terminal ABC1 PF03109.16 AJZ75948.1 - 1e-24 87.0 0.8 3.4e-24 85.3 0.1 2.2 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 AJZ75948.1 - 0.00078 18.9 1.2 0.0016 17.8 0.7 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 AJZ75948.1 - 0.02 14.8 0.1 0.18 11.7 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4795 PF16043.5 AJZ75948.1 - 0.29 10.7 1.9 0.4 10.2 0.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) NPCBM_assoc PF10633.9 AJZ75949.1 - 0.00028 21.1 3.4 0.44 10.8 0.3 4.2 4 0 0 4 4 4 1 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF11 PF01345.18 AJZ75949.1 - 0.0011 19.2 4.4 0.025 14.8 3.2 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF11 FeoB_associated PF12669.7 AJZ75949.1 - 0.0028 18.0 0.8 0.0049 17.2 0.8 1.3 1 0 0 1 1 1 1 FeoB-associated Cys-rich membrane protein DUF4832 PF16116.5 AJZ75949.1 - 0.0068 16.3 0.4 0.011 15.6 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4832) Arrestin_C PF02752.22 AJZ75949.1 - 0.11 13.0 3.5 0.44 11.0 2.5 2.3 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain CARDB PF07705.11 AJZ75949.1 - 0.15 12.3 9.3 0.36 11.1 5.9 3.2 2 1 0 3 3 3 0 CARDB DUF1573 PF07610.11 AJZ75949.1 - 0.22 11.6 4.6 11 6.1 0.3 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1573) Big_7 PF17957.1 AJZ75949.1 - 0.27 12.0 6.6 6.7 7.6 4.5 3.2 2 1 1 3 3 3 0 Bacterial Ig domain FtsX PF02687.21 AJZ75950.1 - 2.3e-14 53.6 1.8 2.3e-14 53.6 1.8 2.4 3 0 0 3 3 3 1 FtsX-like permease family MacB_PCD PF12704.7 AJZ75950.1 - 9.3e-14 52.2 0.8 1.5e-13 51.6 0.8 1.3 1 0 0 1 1 1 1 MacB-like periplasmic core domain HTH_24 PF13412.6 AJZ75951.1 - 1.6e-17 62.8 4.9 1.2e-08 34.3 1.0 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AJZ75951.1 - 2.1e-17 62.6 1.2 3.4e-09 36.4 0.1 2.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain MarR PF01047.22 AJZ75951.1 - 7.8e-07 28.9 2.9 0.00025 20.9 0.5 2.6 3 0 0 3 3 2 2 MarR family TrmB PF01978.19 AJZ75951.1 - 2.9e-05 23.9 0.0 0.0012 18.7 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Mga PF05043.13 AJZ75951.1 - 5.8e-05 23.6 0.1 0.016 15.8 0.1 2.7 2 0 0 2 2 2 1 Mga helix-turn-helix domain HTH_5 PF01022.20 AJZ75951.1 - 6e-05 22.8 1.1 0.0001 22.1 0.1 1.9 2 0 0 2 2 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AJZ75951.1 - 6.5e-05 22.8 1.9 0.00094 19.1 0.6 2.5 2 0 0 2 2 2 1 HTH domain MarR_2 PF12802.7 AJZ75951.1 - 7e-05 22.6 0.0 0.0031 17.4 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_Mga PF08280.11 AJZ75951.1 - 7.5e-05 22.7 1.3 0.00054 19.9 0.9 2.5 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_9 PF08221.11 AJZ75951.1 - 0.00026 21.0 0.4 0.18 11.9 0.1 2.9 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_41 PF14502.6 AJZ75951.1 - 0.0021 17.7 0.1 0.0061 16.2 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain TFIIE_alpha PF02002.17 AJZ75951.1 - 0.004 17.0 0.4 0.028 14.3 0.1 2.3 2 0 0 2 2 2 1 TFIIE alpha subunit HTH_36 PF13730.6 AJZ75951.1 - 0.0047 16.8 0.4 0.011 15.6 0.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Trp_repressor PF01371.19 AJZ75951.1 - 0.011 15.8 1.8 0.91 9.7 0.1 2.7 3 0 0 3 3 2 0 Trp repressor protein HxlR PF01638.17 AJZ75951.1 - 0.012 15.5 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 HxlR-like helix-turn-helix HTH_7 PF02796.15 AJZ75951.1 - 0.02 15.0 0.3 0.13 12.3 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_DeoR PF08220.12 AJZ75951.1 - 0.022 14.5 0.3 0.058 13.1 0.3 1.8 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_27 PF13463.6 AJZ75951.1 - 0.031 14.8 0.3 2 9.0 0.1 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 AJZ75951.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_26 PF13443.6 AJZ75951.1 - 0.053 14.0 0.3 0.14 12.6 0.3 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_40 PF14493.6 AJZ75951.1 - 0.08 13.4 1.2 0.45 11.0 0.0 2.9 4 1 0 4 4 2 0 Helix-turn-helix domain HTH_10 PF04967.12 AJZ75951.1 - 0.12 12.1 0.7 3.5 7.5 0.1 2.5 2 0 0 2 2 2 0 HTH DNA binding domain NUDIX PF00293.28 AJZ75952.1 - 1.1e-19 70.8 0.0 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain PhoU PF01895.19 AJZ75953.1 - 6.8e-11 42.5 11.9 1.4e-08 35.0 2.5 2.9 2 0 0 2 2 2 2 PhoU domain MazE_antitoxin PF04014.18 AJZ75953.1 - 9.5e-06 25.4 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin GHMP_kinases_N PF00288.26 AJZ75954.1 - 6.4e-10 39.1 0.3 1.2e-09 38.2 0.3 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AJZ75954.1 - 0.052 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal LIFR_N PF18207.1 AJZ75954.1 - 0.2 12.1 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain PPS_PS PF02006.16 AJZ75955.1 - 2.1e-63 213.0 1.9 3.2e-63 212.4 1.9 1.2 1 0 0 1 1 1 1 Phosphopantothenate/pantothenate synthetase Pantoate_transf PF02548.15 AJZ75956.1 - 1.4e-108 362.2 3.2 1.6e-108 362.0 3.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 AJZ75956.1 - 0.00063 19.3 1.2 0.0017 17.8 1.2 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DFP PF04127.15 AJZ75957.1 - 2.2e-56 190.7 2.6 4.2e-54 183.2 0.7 2.6 3 0 0 3 3 3 2 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 AJZ75957.1 - 1.3e-33 116.0 2.0 1.4e-33 115.8 0.4 1.9 2 0 0 2 2 2 1 Flavoprotein NAD_binding_7 PF13241.6 AJZ75957.1 - 0.0026 18.2 0.4 0.15 12.5 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding BRCT PF00533.26 AJZ75957.1 - 0.036 14.5 0.1 0.65 10.4 0.0 2.9 3 1 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain YjeF_N PF03853.15 AJZ75957.1 - 0.048 13.5 0.0 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 YjeF-related protein N-terminus Pyr_redox PF00070.27 AJZ75957.1 - 0.13 12.9 0.9 44 4.7 0.0 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Beta_propel PF09826.9 AJZ75958.1 - 1.4e-154 515.8 17.0 1.6e-154 515.5 17.0 1.0 1 0 0 1 1 1 1 Beta propeller domain Catalase-rel PF06628.12 AJZ75958.1 - 0.11 12.7 0.5 26 5.1 0.1 2.5 2 0 0 2 2 2 0 Catalase-related immune-responsive Aldedh PF00171.22 AJZ75959.1 - 5.7e-137 457.0 0.0 7.2e-137 456.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DndB PF14072.6 AJZ75960.1 - 1.1e-09 38.0 1.1 1.2e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 DNA-sulfur modification-associated Hjc PF01870.18 AJZ75960.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) Helicase_C_2 PF13307.6 AJZ75961.1 - 1.8e-15 57.5 0.0 3.8e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 AJZ75961.1 - 4.6e-09 36.5 2.4 9.6e-09 35.5 0.0 2.7 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AJZ75961.1 - 0.00016 21.5 0.2 0.0067 16.2 0.2 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 AJZ75961.1 - 0.00044 19.9 0.1 0.00044 19.9 0.1 2.4 2 0 0 2 2 2 1 DEAD_2 AAA_22 PF13401.6 AJZ75961.1 - 0.0039 17.5 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 AJZ75961.1 - 0.016 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 AJZ75961.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 AJZ75961.1 - 0.062 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 AJZ75961.1 - 0.065 12.9 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AJZ75961.1 - 0.092 11.8 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 AJZ75961.1 - 0.24 10.9 0.0 0.5 9.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 AJZ75962.1 - 2.7e-11 43.7 0.0 5.2e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AJZ75962.1 - 1.1e-07 32.6 0.2 5.2e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AJZ75962.1 - 2.4e-06 27.9 0.0 4.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AJZ75962.1 - 3.6e-06 26.9 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AJZ75962.1 - 4.6e-05 23.3 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 AJZ75962.1 - 0.00047 19.8 0.0 0.00079 19.1 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 AJZ75962.1 - 0.00069 19.7 0.0 0.026 14.6 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain ComGF PF15980.5 AJZ75962.1 - 0.012 15.9 0.7 0.024 15.0 0.7 1.5 1 0 0 1 1 1 0 Putative Competence protein ComGF Acetyltransf_4 PF13420.7 AJZ75962.1 - 0.016 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AJZ75962.1 - 0.038 14.1 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Glyco_trans_4_5 PF16994.5 AJZ75962.1 - 0.053 13.1 1.2 0.1 12.2 1.2 1.5 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Gly_acyl_tr_C PF08444.10 AJZ75962.1 - 0.11 12.8 0.3 0.84 9.9 0.0 2.3 1 1 1 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Eapp_C PF10238.9 AJZ75963.1 - 0.0035 17.4 0.3 0.0041 17.2 0.3 1.1 1 0 0 1 1 1 1 E2F-associated phosphoprotein V_ATPase_I PF01496.19 AJZ75963.1 - 0.044 11.7 2.0 0.046 11.6 2.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 AJZ75963.1 - 0.054 13.2 1.7 0.059 13.1 1.7 1.1 1 0 0 1 1 1 0 Connexin O-antigen_lig PF13425.6 AJZ75963.1 - 0.11 11.3 2.1 0.12 11.2 2.1 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PPL5 PF18168.1 AJZ75963.1 - 0.13 11.5 3.2 0.15 11.3 3.2 1.0 1 0 0 1 1 1 0 Prim-pol family 5 EMC3_TMCO1 PF01956.16 AJZ75963.1 - 0.18 11.5 1.4 0.21 11.3 1.4 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RNA_pol_Rpc4 PF05132.14 AJZ75963.1 - 1.6 9.1 10.5 1.8 9.0 10.5 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 NARP1 PF12569.8 AJZ75963.1 - 1.7 7.5 12.3 1.9 7.3 12.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-C2H2_4 PF13894.6 AJZ75964.1 - 0.00079 20.1 6.1 0.092 13.6 0.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 AJZ75964.1 - 0.00082 19.7 8.1 0.039 14.4 0.7 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-FCS PF06467.14 AJZ75964.1 - 0.0056 16.6 1.3 1.3 9.0 0.1 2.2 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif DZR PF12773.7 AJZ75964.1 - 0.0094 16.0 0.4 0.014 15.4 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C2HC5 PF06221.13 AJZ75964.1 - 0.017 15.1 2.4 1.8 8.6 0.2 2.1 1 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type TFIIS_C PF01096.18 AJZ75964.1 - 0.03 14.2 0.4 0.044 13.6 0.4 1.3 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) LIM PF00412.22 AJZ75964.1 - 0.031 14.5 5.5 0.039 14.2 5.5 1.2 1 0 0 1 1 1 0 LIM domain zf-C3HC PF07967.13 AJZ75964.1 - 0.079 13.0 2.6 1.1 9.3 0.2 2.0 1 1 1 2 2 2 0 C3HC zinc finger-like zf-C2H2_6 PF13912.6 AJZ75964.1 - 0.079 13.0 9.0 0.18 11.9 2.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-DNL PF05180.12 AJZ75964.1 - 0.093 12.7 4.5 0.12 12.3 4.5 1.2 1 0 0 1 1 1 0 DNL zinc finger A2L_zn_ribbon PF08792.10 AJZ75964.1 - 0.33 10.7 3.9 0.95 9.3 0.2 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.15 AJZ75964.1 - 1.1 9.3 7.4 1.8 8.6 1.9 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 AJZ75964.1 - 1.6 9.1 10.2 0.13 12.6 2.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 AJZ75964.1 - 2.5 8.7 12.0 0.4 11.2 3.2 2.8 2 1 1 3 3 3 0 Zinc-finger double domain DUF629 PF04780.12 AJZ75964.1 - 7.2 5.0 9.7 1.5 7.2 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) HTH_45 PF14947.6 AJZ75965.1 - 2e-09 37.3 0.2 2.6e-09 36.9 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix FtsK_gamma PF09397.10 AJZ75965.1 - 0.0088 15.8 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 Ftsk gamma domain DUF5343 PF17278.2 AJZ75965.1 - 0.012 15.7 0.1 0.015 15.4 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5343) P-II PF00543.22 AJZ75966.1 - 8.6e-06 26.3 0.0 8.1e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Nitrogen regulatory protein P-II Pyr_redox_2 PF07992.14 AJZ75967.1 - 1.9e-47 161.9 0.0 2.3e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJZ75967.1 - 9.3e-14 51.8 0.8 6.3e-09 36.3 0.4 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AJZ75967.1 - 0.0013 18.4 0.1 0.38 10.3 0.2 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AJZ75967.1 - 0.034 14.2 0.0 24 4.9 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 AJZ75967.1 - 0.17 11.0 0.0 3.5 6.7 0.0 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 AJZ75967.1 - 0.23 10.5 1.6 7.2 5.6 0.4 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 AJZ75967.1 - 2.8 7.1 5.2 10 5.3 1.6 3.1 2 2 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2283 PF10049.9 AJZ75968.1 - 2.1e-09 37.5 0.0 2.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2283) DUF4258 PF14076.6 AJZ75969.1 - 6.2e-05 23.3 0.0 7.8e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4258) TOBE PF03459.17 AJZ75970.1 - 0.02 15.2 0.0 0.069 13.5 0.0 1.8 2 0 0 2 2 2 0 TOBE domain SNF2_assoc PF08455.10 AJZ75971.1 - 0.00043 19.4 5.4 0.00051 19.2 5.0 1.4 1 1 0 1 1 1 1 Bacterial SNF2 helicase associated ACT_7 PF13840.6 AJZ75971.1 - 0.0006 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 ACT domain SecD-TM1 PF13721.6 AJZ75971.1 - 0.0073 16.7 0.3 0.023 15.2 0.1 1.9 2 0 0 2 2 2 1 SecD export protein N-terminal TM region HSP20 PF00011.21 AJZ75972.1 - 8.9e-10 38.6 3.4 3.2e-08 33.6 3.4 2.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AJZ75972.1 - 7.3e-07 28.6 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA AAA PF00004.29 AJZ75973.1 - 8.4e-100 330.4 0.0 2.8e-49 166.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AJZ75973.1 - 1.5e-27 95.1 2.3 1.9e-14 53.1 0.1 3.0 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 AJZ75973.1 - 3.4e-21 75.2 0.1 1.4e-20 73.3 0.1 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 AJZ75973.1 - 1.5e-17 64.3 0.0 2e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 AJZ75973.1 - 2e-15 56.9 0.0 2.2e-08 34.0 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AJZ75973.1 - 1.1e-14 54.6 0.5 1.3e-06 28.4 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AJZ75973.1 - 2.3e-13 50.9 0.0 4.5e-05 23.9 0.0 3.6 2 1 0 3 3 3 2 AAA ATPase domain TIP49 PF06068.13 AJZ75973.1 - 4e-10 39.4 0.1 0.00057 19.2 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 AJZ75973.1 - 9.9e-10 38.8 1.7 0.011 16.0 0.1 4.1 2 2 2 4 4 4 2 AAA domain AAA_33 PF13671.6 AJZ75973.1 - 1.8e-09 37.9 0.0 0.00025 21.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 AJZ75973.1 - 3.1e-09 36.5 0.2 8.9e-09 35.0 0.2 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 AJZ75973.1 - 5.5e-09 36.2 0.0 0.0014 18.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 AJZ75973.1 - 1.3e-08 35.5 0.0 0.00092 19.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 AJZ75973.1 - 7.7e-08 32.0 0.3 0.0072 15.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AJZ75973.1 - 9.6e-08 32.0 0.0 0.019 14.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 AJZ75973.1 - 1.8e-07 31.5 0.0 0.025 15.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 AJZ75973.1 - 4.2e-07 29.9 0.3 0.035 13.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 AJZ75973.1 - 7.4e-07 29.0 0.5 0.23 11.2 0.0 4.4 4 1 0 4 4 4 2 Sigma-54 interaction domain AAA_28 PF13521.6 AJZ75973.1 - 9.5e-07 29.2 0.1 0.039 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 AJZ75973.1 - 1.1e-06 28.3 0.1 0.055 13.0 0.0 2.7 3 0 0 3 3 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 AJZ75973.1 - 3.1e-06 26.6 0.2 0.025 13.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_3 PF07726.11 AJZ75973.1 - 6.9e-06 26.0 0.0 0.071 13.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AJZ75973.1 - 8.3e-06 26.4 0.0 0.28 11.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter TsaE PF02367.17 AJZ75973.1 - 8.8e-06 25.7 0.4 0.21 11.6 0.0 3.0 3 1 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 AJZ75973.1 - 1.1e-05 25.1 1.0 0.88 9.1 0.0 3.5 2 1 0 3 3 3 2 AAA domain Parvo_NS1 PF01057.17 AJZ75973.1 - 1.5e-05 24.2 0.2 0.036 13.2 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 AJZ75973.1 - 2e-05 23.9 0.0 0.13 11.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ATPase PF06745.13 AJZ75973.1 - 8.1e-05 22.1 2.0 0.54 9.6 0.1 3.6 2 1 0 3 3 3 2 KaiC AAA_11 PF13086.6 AJZ75973.1 - 8.5e-05 22.5 0.0 0.37 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 AJZ75973.1 - 0.00012 21.9 1.0 0.19 11.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain PhoH PF02562.16 AJZ75973.1 - 0.00012 21.6 0.5 0.45 9.9 0.1 2.6 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.6 AJZ75973.1 - 0.00026 21.1 0.0 0.48 10.5 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Bac_DnaA PF00308.18 AJZ75973.1 - 0.00026 20.9 0.0 0.1 12.4 0.0 3.0 3 1 0 3 3 2 1 Bacterial dnaA protein DUF2075 PF09848.9 AJZ75973.1 - 0.00055 19.3 0.1 0.64 9.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 AJZ75973.1 - 0.00081 19.8 0.0 2.5 8.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AJZ75973.1 - 0.001 19.4 2.1 1.1 9.6 0.0 3.2 2 1 1 3 3 2 1 AAA domain ATPase_2 PF01637.18 AJZ75973.1 - 0.0016 18.4 1.0 0.66 9.8 0.0 3.6 2 2 2 4 4 3 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 AJZ75973.1 - 0.0023 17.1 0.2 1.9 7.6 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain Vps4_C PF09336.10 AJZ75973.1 - 0.0024 17.9 0.5 0.41 10.7 0.1 3.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain TniB PF05621.11 AJZ75973.1 - 0.0024 17.3 0.0 1 8.7 0.0 2.9 3 0 0 3 3 2 1 Bacterial TniB protein NACHT PF05729.12 AJZ75973.1 - 0.0028 17.6 1.3 2.4 8.0 0.0 3.5 3 1 1 4 4 3 1 NACHT domain Guanylate_kin PF00625.21 AJZ75973.1 - 0.0047 16.6 2.1 15 5.3 0.0 4.6 5 1 1 6 6 4 0 Guanylate kinase LID PF17916.1 AJZ75973.1 - 0.008 15.8 0.1 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 LIM interaction domain (LID) NTPase_1 PF03266.15 AJZ75973.1 - 0.011 15.7 3.8 4.4 7.2 0.0 4.0 3 1 1 4 4 3 0 NTPase Rad17 PF03215.15 AJZ75973.1 - 0.011 15.6 0.0 0.98 9.3 0.0 2.9 2 1 0 2 2 2 0 Rad17 P-loop domain ResIII PF04851.15 AJZ75973.1 - 0.014 15.4 0.0 2.6 8.0 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 AJZ75973.1 - 0.018 14.1 0.0 6.5 5.7 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.25 AJZ75973.1 - 0.02 14.5 0.1 10 5.7 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.12 AJZ75973.1 - 0.04 13.8 0.2 1.5 8.6 0.0 2.8 2 1 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein KAP_NTPase PF07693.14 AJZ75973.1 - 0.041 13.1 0.1 3.8 6.6 0.0 3.0 2 1 0 3 3 3 0 KAP family P-loop domain PIF1 PF05970.14 AJZ75973.1 - 0.048 12.8 0.0 4.4 6.4 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase IPT PF01745.16 AJZ75973.1 - 0.071 12.5 0.3 4.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Isopentenyl transferase AFG1_ATPase PF03969.16 AJZ75973.1 - 0.074 11.9 0.1 4.9 5.9 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Viral_helicase1 PF01443.18 AJZ75973.1 - 0.091 12.5 0.0 1.7 8.4 0.0 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase PPV_E1_C PF00519.17 AJZ75973.1 - 0.13 11.0 0.0 1.7 7.4 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase Citrate_ly_lig PF08218.11 AJZ75973.1 - 0.15 11.7 0.1 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain Zw10 PF06248.13 AJZ75973.1 - 0.25 9.8 0.7 0.36 9.3 0.2 1.5 2 0 0 2 2 1 0 Centromere/kinetochore Zw10 Cytidylate_kin PF02224.18 AJZ75973.1 - 0.26 11.0 1.6 9.3 5.9 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase Polyketide_cyc2 PF10604.9 AJZ75974.1 - 1.9e-05 25.0 0.0 2.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AJZ75974.1 - 0.07 13.3 0.0 0.083 13.1 0.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Chlam_PMP PF02415.17 AJZ75974.1 - 0.13 12.8 0.5 0.27 11.8 0.5 1.5 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Fer4 PF00037.27 AJZ75975.1 - 1e-10 40.9 11.2 5.1e-07 29.3 0.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJZ75975.1 - 7.3e-09 36.1 3.7 9.8e-09 35.7 3.7 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJZ75975.1 - 7e-08 32.5 1.6 9.9e-08 32.0 1.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AJZ75975.1 - 4.3e-07 29.7 8.8 0.0013 18.7 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AJZ75975.1 - 5.6e-06 26.4 4.3 2.1e-05 24.6 4.4 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AJZ75975.1 - 7.8e-06 25.7 7.4 0.01 15.9 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AJZ75975.1 - 7.2e-05 23.2 4.0 0.12 12.9 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 AJZ75975.1 - 0.00026 21.3 6.9 0.081 13.5 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AJZ75975.1 - 0.00029 20.9 8.7 0.011 15.8 9.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AJZ75975.1 - 0.00062 20.7 6.2 0.075 14.0 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 AJZ75975.1 - 0.00066 20.5 3.3 0.12 13.2 0.6 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AJZ75975.1 - 0.0014 19.4 11.2 0.097 13.7 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AJZ75975.1 - 0.0053 17.2 5.8 0.048 14.1 5.8 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AJZ75975.1 - 0.034 14.7 6.8 1.1 9.9 6.8 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AJZ75975.1 - 0.091 13.5 10.8 0.59 10.9 2.3 2.8 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 AJZ75975.1 - 0.62 10.3 10.1 1.5 9.0 2.9 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Aminotran_5 PF00266.19 AJZ75976.1 - 1.2e-62 212.1 0.0 1.4e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AJZ75976.1 - 2.7e-09 36.7 0.0 3.6e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AJZ75976.1 - 0.00071 18.9 0.0 0.00091 18.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 AJZ75976.1 - 0.00076 18.3 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 AJZ75976.1 - 0.0012 18.2 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AJZ75976.1 - 0.061 11.8 0.0 0.25 9.9 0.0 1.8 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme AsnC_trans_reg PF01037.21 AJZ75977.1 - 6.9e-09 35.6 0.3 8.5e-09 35.3 0.3 1.2 1 1 0 1 1 1 1 Lrp/AsnC ligand binding domain ACT_4 PF13291.6 AJZ75977.1 - 0.0089 16.6 1.1 0.012 16.2 1.1 1.2 1 0 0 1 1 1 1 ACT domain NapD PF03927.13 AJZ75977.1 - 0.01 15.9 1.0 0.014 15.4 1.0 1.4 1 1 0 1 1 1 0 NapD protein Cyclase PF04199.13 AJZ75978.1 - 1.1e-33 116.3 0.0 1.4e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase DUF3489 PF11994.8 AJZ75978.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Radical_SAM PF04055.21 AJZ75979.1 - 4.2e-09 37.0 0.0 6.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AJZ75979.1 - 0.012 15.9 0.3 0.036 14.3 0.3 1.9 1 1 0 1 1 1 0 4Fe-4S single cluster domain DNA_RNApol_7kD PF03604.13 AJZ75979.1 - 0.073 12.8 3.5 1.1 8.9 0.1 2.8 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 AJZ75979.1 - 0.98 9.4 6.9 13 5.8 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-FCS PF06467.14 AJZ75979.1 - 3.4 7.7 13.8 0.25 11.3 0.4 3.2 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DSPc PF00782.20 AJZ75980.1 - 1.8e-19 69.9 0.0 2.1e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AJZ75980.1 - 7.4e-10 38.8 0.0 1.3e-09 38.0 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 AJZ75980.1 - 3.8e-07 30.3 0.0 5.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 AJZ75980.1 - 0.00045 20.3 0.0 0.00065 19.7 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 AJZ75980.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 AJZ75980.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF442 PF04273.13 AJZ75980.1 - 0.12 12.5 0.0 0.72 10.0 0.0 2.0 2 0 0 2 2 2 0 Putative phosphatase (DUF442) SnoaL_2 PF12680.7 AJZ75981.1 - 5.3e-11 43.1 0.0 6e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AJZ75981.1 - 9.9e-05 22.1 0.1 0.0002 21.2 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase LEH PF07858.12 AJZ75981.1 - 0.00074 19.6 0.1 0.001 19.2 0.1 1.3 1 1 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain DUF4440 PF14534.6 AJZ75981.1 - 0.0024 18.2 0.0 0.0027 18.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) WI12 PF07107.11 AJZ75981.1 - 0.066 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Wound-induced protein WI12 DUF3364 PF11844.8 AJZ75981.1 - 0.07 13.4 0.4 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) RNA_pol_L_2 PF13656.6 AJZ75983.1 - 2.8e-10 39.8 0.0 3.2e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TFIIS_C PF01096.18 AJZ75984.1 - 1.5e-20 72.8 5.0 1.5e-20 72.8 5.0 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 AJZ75984.1 - 0.0014 18.5 15.3 1.1 9.3 9.3 4.0 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 AJZ75984.1 - 0.0016 18.4 12.2 0.015 15.3 3.3 2.5 2 1 0 2 2 2 2 Double zinc ribbon zinc_ribbon_13 PF09855.9 AJZ75984.1 - 0.01 16.0 3.8 0.01 16.0 3.8 3.7 3 1 1 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Ribosomal_L37e PF01907.19 AJZ75984.1 - 0.02 15.1 9.5 0.54 10.5 3.5 3.1 3 0 0 3 3 3 0 Ribosomal protein L37e Zn-ribbon_8 PF09723.10 AJZ75984.1 - 0.023 14.8 11.4 5.7 7.1 0.0 4.2 3 1 2 5 5 5 0 Zinc ribbon domain zf-SNAP50_C PF12251.8 AJZ75984.1 - 0.057 13.1 0.8 0.057 13.1 0.8 1.8 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal zinc_ribbon_4 PF13717.6 AJZ75984.1 - 0.093 12.7 0.6 0.093 12.7 0.6 4.1 3 1 1 4 4 4 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 AJZ75984.1 - 0.19 11.5 14.5 3.7 7.4 0.1 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain MCM_OB PF17207.3 AJZ75984.1 - 0.49 10.2 5.4 0.37 10.7 0.3 2.2 1 1 1 2 2 2 0 MCM OB domain Baculo_LEF5_C PF11792.8 AJZ75984.1 - 0.83 9.4 13.0 0.071 12.8 1.7 3.6 3 1 1 4 4 4 0 Baculoviridae late expression factor 5 C-terminal domain Rubredoxin_2 PF18073.1 AJZ75984.1 - 1.7 8.5 22.4 2.3 8.0 0.3 4.0 4 0 0 4 4 4 0 Rubredoxin metal binding domain zinc_ribbon_2 PF13240.6 AJZ75984.1 - 1.8 8.4 19.0 5.7 6.8 0.1 4.1 3 1 0 3 3 3 0 zinc-ribbon domain zf_UBZ PF18439.1 AJZ75984.1 - 2 8.1 16.0 7.2 6.3 0.1 4.1 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 AJZ75984.1 - 3 7.9 16.4 0.9 9.6 3.7 3.2 2 2 1 3 3 3 0 Transposase zinc-ribbon domain zf-CHY PF05495.12 AJZ75984.1 - 4 8.0 11.6 2.3e+02 2.4 11.6 2.5 1 1 0 1 1 1 0 CHY zinc finger C1_4 PF07975.12 AJZ75984.1 - 4.7 7.5 10.2 1.5 9.1 0.4 3.1 1 1 1 2 2 2 0 TFIIH C1-like domain Elf1 PF05129.13 AJZ75984.1 - 7.7 6.6 9.9 2.7 8.1 3.9 2.9 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like PCNA_N PF00705.18 AJZ75985.1 - 9.5e-19 67.4 0.0 5.4e-18 64.9 0.0 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 AJZ75985.1 - 3.2e-15 56.4 0.1 6.5e-14 52.2 0.0 2.5 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 AJZ75985.1 - 0.02 14.4 0.0 0.027 13.9 0.0 1.3 1 1 0 1 1 1 0 Rad9 Ecm33 PF12454.8 AJZ75985.1 - 0.13 12.4 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein AA_kinase PF00696.28 AJZ75986.1 - 2.1e-51 174.9 0.2 3.3e-51 174.2 0.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 AJZ75986.1 - 1.4e-19 69.6 3.3 8.1e-13 48.0 0.2 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 AJZ75986.1 - 3.3e-16 58.8 0.3 1.1e-09 37.9 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 AJZ75986.1 - 0.26 11.3 1.3 0.88 9.6 0.0 2.4 3 0 0 3 3 3 0 ACT domain TP_methylase PF00590.20 AJZ75988.1 - 7.6e-38 130.6 0.0 8.8e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases tRNA-synt_1b PF00579.25 AJZ75989.1 - 3.5e-40 138.2 0.0 4.3e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DegT_DnrJ_EryC1 PF01041.17 AJZ75991.1 - 5.8e-114 381.2 0.1 6.8e-114 380.9 0.1 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AJZ75991.1 - 3.6e-09 36.3 0.0 5.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AJZ75991.1 - 2.2e-08 33.1 0.3 3.4e-08 32.4 0.3 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AJZ75991.1 - 6.8e-07 28.6 0.4 1e-06 28.0 0.4 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AJZ75991.1 - 1e-05 25.0 0.1 4.2e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase ComK PF06338.11 AJZ75991.1 - 0.043 13.5 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 ComK protein MtrA PF04208.14 AJZ75992.1 - 2.5e-21 76.1 0.3 2.9e-21 75.9 0.3 1.0 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit A dUTPase_2 PF08761.11 AJZ75993.1 - 2.1e-18 67.1 6.6 3.8e-14 53.2 0.2 2.0 1 1 1 2 2 2 2 dUTPase PRA-PH PF01503.17 AJZ75993.1 - 0.00038 20.9 0.0 0.00046 20.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase T2SSL PF05134.13 AJZ75993.1 - 0.095 12.0 0.0 0.1 11.9 0.0 1.0 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein L PfkB PF00294.24 AJZ75994.1 - 1.6e-21 76.9 0.1 4e-21 75.6 0.1 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AJZ75994.1 - 0.00062 19.2 0.0 0.00096 18.6 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 AJZ75994.1 - 0.058 12.9 0.7 1.9 7.9 0.1 2.5 2 1 0 2 2 2 0 Carbohydrate kinase LEA_2 PF03168.13 AJZ75995.1 - 0.00068 20.1 0.0 0.0018 18.8 0.0 1.7 1 1 0 1 1 1 1 Late embryogenesis abundant protein DUF2393 PF09624.10 AJZ75995.1 - 0.13 12.3 0.3 0.2 11.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF2673 PF10880.8 AJZ75997.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) Pro_isomerase PF00160.21 AJZ75998.1 - 3.5e-50 170.3 0.1 4e-50 170.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HTH_23 PF13384.6 AJZ75999.1 - 0.00055 19.7 0.0 0.0061 16.3 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain GntR PF00392.21 AJZ75999.1 - 0.051 13.2 0.1 0.09 12.4 0.1 1.6 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF87 PF01935.17 AJZ75999.1 - 0.054 13.6 0.2 0.059 13.4 0.2 1.0 1 0 0 1 1 1 0 Helicase HerA, central domain HTH_IclR PF09339.10 AJZ75999.1 - 0.062 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain TrmB PF01978.19 AJZ75999.1 - 0.071 13.0 0.1 0.11 12.4 0.1 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2730 PF10805.8 AJZ76000.1 - 0.0011 19.0 1.9 0.0011 19.0 1.9 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2730) DUF641 PF04859.12 AJZ76000.1 - 0.0037 17.6 3.3 0.0043 17.4 2.6 1.5 1 1 0 1 1 1 1 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 AJZ76000.1 - 0.0095 16.1 0.4 0.011 15.8 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus FlxA PF14282.6 AJZ76000.1 - 0.024 14.6 1.1 0.032 14.2 1.1 1.2 1 0 0 1 1 1 0 FlxA-like protein FAM76 PF16046.5 AJZ76000.1 - 0.035 13.5 1.3 0.045 13.1 1.3 1.1 1 0 0 1 1 1 0 FAM76 protein DUF1192 PF06698.11 AJZ76000.1 - 0.039 14.0 9.3 0.57 10.3 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) CheY-binding PF09078.11 AJZ76000.1 - 0.12 12.5 1.4 7 6.9 0.1 2.7 2 1 1 3 3 3 0 CheY binding DUF3810 PF12725.7 AJZ76000.1 - 0.13 11.6 6.1 0.35 10.2 6.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Mito_fiss_reg PF05308.11 AJZ76000.1 - 0.19 11.8 3.9 0.25 11.4 3.9 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Bap31_Bap29_C PF18035.1 AJZ76000.1 - 2.4 8.3 6.9 2.8 8.0 1.6 2.3 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain FMN_red PF03358.15 AJZ76002.1 - 3.5e-23 82.0 0.0 4.5e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AJZ76002.1 - 3.9e-09 36.5 0.0 7.8e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold DUF2951 PF11166.8 AJZ76002.1 - 0.12 12.6 0.0 10 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Nitroreductase PF00881.24 AJZ76003.1 - 4.4e-27 95.2 0.0 8.1e-27 94.3 0.0 1.4 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AJZ76003.1 - 0.027 14.1 0.2 0.77 9.3 0.0 2.2 1 1 1 2 2 2 0 Putative TM nitroreductase CopD PF05425.13 AJZ76004.1 - 3.7e-15 56.2 2.7 6.6e-15 55.4 2.7 1.4 1 0 0 1 1 1 1 Copper resistance protein D DUF4149 PF13664.6 AJZ76004.1 - 0.0064 16.8 2.0 0.0064 16.8 2.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) PEMT PF04191.13 AJZ76004.1 - 0.19 12.1 0.2 0.19 12.1 0.2 2.1 3 1 0 3 3 3 0 Phospholipid methyltransferase DUF3278 PF11683.8 AJZ76004.1 - 0.89 9.7 7.3 0.072 13.2 2.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF4131 PF13567.6 AJZ76004.1 - 1.4 8.5 4.2 2.8 7.5 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) RTC PF01137.21 AJZ76005.1 - 6.2e-74 247.9 0.1 7.1e-74 247.7 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase CTP_transf_like PF01467.26 AJZ76006.1 - 8.6e-16 58.4 0.1 1.5e-15 57.7 0.1 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Aminotran_5 PF00266.19 AJZ76007.1 - 2e-34 119.1 0.0 2.6e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AJZ76007.1 - 3e-06 26.0 0.1 4.9e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 AJZ76007.1 - 0.0036 16.0 0.1 0.073 11.7 0.0 2.2 1 1 1 2 2 2 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AJZ76007.1 - 0.0065 15.8 0.0 0.016 14.5 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Lipoprotein_9 PF03180.14 AJZ76007.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 NLPA lipoprotein FKBP_C PF00254.28 AJZ76008.1 - 5.6e-12 45.8 0.4 2.8e-11 43.6 0.4 2.4 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP26_C PF18046.1 AJZ76008.1 - 3.9e-10 39.7 0.4 1.1e-09 38.2 0.4 1.8 1 0 0 1 1 1 1 FKBP26_C-terminal Pribosyltran_N PF13793.6 AJZ76009.1 - 2.5e-24 85.5 0.0 1.6e-23 82.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 AJZ76009.1 - 3.5e-15 55.9 3.0 5e-15 55.4 0.2 2.4 2 1 0 2 2 2 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 AJZ76009.1 - 3.3e-12 46.8 5.2 2.1e-11 44.2 1.2 2.6 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain UPRTase PF14681.6 AJZ76009.1 - 3.1e-05 23.5 0.0 6.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Asp_Glu_race PF01177.22 AJZ76009.1 - 0.0014 18.5 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase PRTase_2 PF15609.6 AJZ76009.1 - 0.0053 16.3 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase Glyco_tranf_2_3 PF13641.6 AJZ76009.1 - 0.018 15.0 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 UPF0020 PF01170.18 AJZ76010.1 - 9.1e-18 64.7 0.1 8.1e-17 61.6 0.1 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 AJZ76010.1 - 1.3e-09 38.1 0.1 5.4e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 DNA methylase Methyltransf_31 PF13847.6 AJZ76010.1 - 6.7e-07 29.2 0.2 1e-06 28.6 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJZ76010.1 - 7.9e-07 29.7 0.0 1.5e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AJZ76010.1 - 3e-06 27.0 0.0 4.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AJZ76010.1 - 0.00015 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.16 AJZ76010.1 - 0.00065 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase AviRa PF11599.8 AJZ76010.1 - 0.0012 18.4 0.3 0.11 11.9 0.0 2.2 1 1 1 2 2 2 1 RRNA methyltransferase AviRa PrmA PF06325.13 AJZ76010.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 AJZ76010.1 - 0.0045 16.6 0.1 0.0076 15.8 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.15 AJZ76010.1 - 0.0065 16.2 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_11 PF08241.12 AJZ76010.1 - 0.0066 17.1 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain THUMP PF02926.17 AJZ76010.1 - 0.012 15.7 0.1 0.048 13.8 0.0 2.2 3 1 0 3 3 2 0 THUMP domain Methyltransf_12 PF08242.12 AJZ76010.1 - 0.022 15.5 0.0 0.041 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 AJZ76010.1 - 0.054 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_5 PF01795.19 AJZ76010.1 - 0.058 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 MraW methylase family Methyltransf_23 PF13489.6 AJZ76010.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 AJZ76010.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Lactamase_B_2 PF12706.7 AJZ76011.1 - 8.1e-12 45.1 0.0 5.3e-05 22.8 0.0 2.3 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AJZ76011.1 - 1.2e-07 32.0 0.0 3.7e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 AJZ76011.1 - 0.00056 19.5 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease SIR2 PF02146.17 AJZ76012.1 - 1.5e-53 181.3 0.0 1.8e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 AJZ76012.1 - 0.0021 17.8 0.0 1.1 9.0 0.0 2.6 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain RNA_binding PF01877.17 AJZ76013.1 - 1.9e-14 53.9 0.0 2.9e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 RNA binding DUF2102 PF09875.9 AJZ76013.1 - 0.0086 15.8 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2102) AAA_17 PF13207.6 AJZ76014.1 - 3.6e-15 56.6 0.2 5.1e-15 56.1 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AJZ76014.1 - 6.1e-12 46.2 0.0 8.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK PF00406.22 AJZ76014.1 - 6.6e-05 23.1 0.1 9.3e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.6 AJZ76014.1 - 0.00019 21.6 0.0 0.00026 21.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 AJZ76014.1 - 0.0017 18.3 0.1 0.0048 16.8 0.1 1.8 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_28 PF13521.6 AJZ76014.1 - 0.0017 18.6 0.0 0.0029 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AJZ76014.1 - 0.006 15.9 0.3 0.016 14.5 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin KTI12 PF08433.10 AJZ76014.1 - 0.0067 15.9 0.1 0.012 15.1 0.1 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA PF00004.29 AJZ76014.1 - 0.008 16.6 0.2 0.016 15.6 0.2 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AJZ76014.1 - 0.0092 15.7 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 AJZ76014.1 - 0.017 14.3 0.3 0.029 13.5 0.3 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 AJZ76014.1 - 0.019 14.9 1.2 0.36 10.7 0.2 2.3 1 1 1 2 2 2 0 NTPase Hpr_kinase_C PF07475.12 AJZ76014.1 - 0.026 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain CoaE PF01121.20 AJZ76014.1 - 0.029 14.0 0.2 0.045 13.4 0.0 1.6 2 0 0 2 2 2 0 Dephospho-CoA kinase MeaB PF03308.16 AJZ76014.1 - 0.032 13.2 0.9 0.042 12.8 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 AJZ76014.1 - 0.081 12.6 1.1 0.16 11.7 0.6 1.9 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 AJZ76014.1 - 0.085 13.1 0.4 0.24 11.7 0.4 1.9 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 AJZ76014.1 - 0.086 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_16 PF13191.6 AJZ76014.1 - 0.093 13.1 0.2 0.1 13.0 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 AJZ76014.1 - 0.16 12.5 0.8 0.23 11.9 0.8 1.5 1 1 0 1 1 1 0 ABC transporter LigT_PEase PF02834.16 AJZ76015.1 - 5.3e-24 84.2 0.0 1.4e-12 47.6 0.0 2.0 2 0 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 AJZ76015.1 - 1.1e-11 44.8 0.0 1.3e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.9 AJZ76015.1 - 1.5e-08 34.8 0.0 4.2e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain tRNA_NucTransf2 PF09249.11 AJZ76016.1 - 2.9e-37 127.4 0.1 5.8e-37 126.4 0.1 1.5 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain NTP_transf_2 PF01909.23 AJZ76016.1 - 1.1e-11 44.8 0.0 3e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain SMODS PF18144.1 AJZ76016.1 - 9.3e-05 22.7 0.2 0.00024 21.3 0.2 1.6 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Polbeta PF18765.1 AJZ76016.1 - 0.0019 18.2 0.0 0.0052 16.8 0.0 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase RIO1 PF01163.22 AJZ76017.1 - 0.00066 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 AJZ76017.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 AJZ76017.1 - 0.023 14.3 0.0 0.76 9.3 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 AJZ76017.1 - 0.027 13.8 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HhH-GPD PF00730.25 AJZ76018.1 - 8e-20 71.3 0.0 1.2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein MG2 PF01835.19 AJZ76019.1 - 1.4e-08 35.0 0.0 2.2e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 MG2 domain YbbR PF07949.12 AJZ76019.1 - 0.0078 16.5 3.0 0.011 16.1 0.5 2.4 2 1 0 2 2 2 1 YbbR-like protein FlgD_ig PF13860.6 AJZ76019.1 - 0.13 12.1 0.5 7.9 6.4 0.1 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain His_Me_b4a2 PF18275.1 AJZ76020.1 - 0.016 15.2 4.1 0.02 14.9 3.3 1.6 1 1 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain zf-C2H2_6 PF13912.6 AJZ76020.1 - 1 9.4 7.8 1.6 8.8 0.1 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger Pyr_redox_2 PF07992.14 AJZ76021.1 - 8.8e-28 97.4 0.0 8.1e-27 94.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJZ76021.1 - 1.1e-07 32.2 0.0 0.076 13.6 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AJZ76021.1 - 0.00022 21.4 0.0 0.00044 20.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AJZ76021.1 - 0.00078 19.1 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AJZ76021.1 - 0.0019 18.2 0.0 0.6 10.1 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 AJZ76021.1 - 0.04 13.0 0.0 0.16 11.0 0.0 2.0 3 1 0 3 3 3 0 FAD binding domain Thi4 PF01946.17 AJZ76021.1 - 0.047 12.9 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 AJZ76021.1 - 0.049 12.3 0.1 3 6.5 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.14 AJZ76021.1 - 0.14 10.9 0.0 0.32 9.8 0.0 1.6 1 0 0 1 1 1 0 Tryptophan halogenase adh_short PF00106.25 AJZ76022.1 - 2.8e-62 209.7 1.6 3.4e-62 209.4 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AJZ76022.1 - 1.7e-47 162.0 1.2 2.1e-47 161.7 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJZ76022.1 - 1.6e-13 51.0 0.2 2e-13 50.6 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AJZ76022.1 - 0.0016 17.8 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 AJZ76022.1 - 0.0027 17.2 0.3 0.021 14.3 0.3 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 AJZ76022.1 - 0.084 12.2 0.8 0.24 10.7 0.1 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Wax2_C PF12076.8 AJZ76022.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain zf-AN1 PF01428.16 AJZ76023.1 - 2.8e-12 46.6 8.6 3.9e-12 46.1 8.6 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger zf-BED PF02892.15 AJZ76023.1 - 0.14 12.2 3.9 2.2 8.4 0.2 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.6 AJZ76023.1 - 1.9 9.5 6.4 0.99 10.4 1.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger ATP-synt_8 PF00895.20 AJZ76024.1 - 0.031 14.7 0.1 0.031 14.7 0.1 1.8 2 1 0 2 2 2 0 ATP synthase protein 8 CPBP PF02517.16 AJZ76024.1 - 1.1 9.7 7.0 1.4 9.3 7.0 1.1 1 0 0 1 1 1 0 CPBP intramembrane metalloprotease DUF760 PF05542.11 AJZ76025.1 - 0.05 14.0 0.3 0.096 13.1 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF760) Sld5 PF05916.11 AJZ76025.1 - 0.076 13.5 0.3 0.14 12.6 0.3 1.5 1 1 0 1 1 1 0 GINS complex protein Gln-synt_C PF00120.24 AJZ76026.1 - 2.3e-118 395.1 0.0 2.7e-118 394.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AJZ76026.1 - 1.3e-25 88.9 0.1 3.2e-25 87.7 0.1 1.7 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF3792 PF12670.7 AJZ76027.1 - 0.0026 17.9 9.9 0.0031 17.6 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) Phage_holin_3_6 PF07332.11 AJZ76027.1 - 4.5 7.4 7.4 9.7 6.3 7.4 1.7 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III SHMT PF00464.19 AJZ76028.1 - 2.2e-77 260.3 0.1 3e-77 259.9 0.1 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 AJZ76028.1 - 1.3e-08 34.5 0.1 6.3e-08 32.2 0.1 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AJZ76028.1 - 2.5e-07 30.3 0.0 4.3e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AJZ76028.1 - 6.6e-05 22.0 0.2 0.00014 20.9 0.2 1.6 1 1 0 1 1 1 1 Aminotransferase class-V SelA PF03841.13 AJZ76028.1 - 0.00015 20.9 0.0 0.00031 19.9 0.0 1.5 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase DDR PF08841.10 AJZ76028.1 - 0.081 11.9 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain PolC_DP2 PF03833.13 AJZ76029.1 - 0 1030.8 0.0 0 1030.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 DSX_dimer PF08828.10 AJZ76029.1 - 0.17 11.6 0.0 0.48 10.1 0.0 1.7 1 0 0 1 1 1 0 Doublesex dimerisation domain zinc-ribbons_6 PF07191.12 AJZ76029.1 - 2.4 8.2 14.9 29 4.7 11.2 2.8 2 1 0 2 2 2 0 zinc-ribbons PcrB PF01884.17 AJZ76030.1 - 7.7e-56 189.1 0.1 9.1e-56 188.8 0.1 1.0 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.21 AJZ76030.1 - 1.7e-08 34.2 0.1 2.2e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein IMPDH PF00478.25 AJZ76030.1 - 2.5e-06 26.7 0.0 4e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DpaA_N PF16924.5 AJZ76030.1 - 0.0014 18.7 0.4 0.063 13.4 0.1 2.2 2 0 0 2 2 2 1 Dipicolinate synthase subunit A N-terminal domain ThiG PF05690.14 AJZ76030.1 - 0.0026 17.1 0.4 0.99 8.7 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 AJZ76030.1 - 0.0028 16.9 0.8 0.0059 15.8 0.1 1.7 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Trp_syntA PF00290.20 AJZ76030.1 - 0.0063 15.4 1.4 0.043 12.7 0.1 2.4 2 1 1 3 3 3 1 Tryptophan synthase alpha chain B12-binding PF02310.19 AJZ76030.1 - 0.011 15.7 1.0 3.5 7.7 0.0 3.6 3 1 0 3 3 3 0 B12 binding domain TMP-TENI PF02581.17 AJZ76030.1 - 0.015 14.7 0.1 0.061 12.7 0.0 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase Ribul_P_3_epim PF00834.19 AJZ76030.1 - 0.016 14.6 0.3 0.061 12.7 0.1 1.9 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family NanE PF04131.14 AJZ76030.1 - 0.037 13.2 0.4 1.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 AJZ76030.1 - 0.044 13.0 1.0 0.89 8.7 0.0 2.4 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase Mpt_N PF09176.11 AJZ76030.1 - 0.046 13.8 0.1 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Malic_M PF03949.15 AJZ76030.1 - 0.052 12.8 0.1 0.087 12.1 0.1 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain G3P_antiterm PF04309.12 AJZ76030.1 - 0.12 11.8 2.9 0.24 10.8 0.1 2.5 2 1 1 3 3 3 0 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 AJZ76030.1 - 0.82 9.0 4.7 12 5.1 0.1 2.6 2 1 1 3 3 3 0 Nitronate monooxygenase IBV_3B PF03622.13 AJZ76031.1 - 0.14 12.4 0.4 0.28 11.4 0.1 1.6 2 0 0 2 2 2 0 IBV 3B protein TrmB PF01978.19 AJZ76032.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 AJZ76032.1 - 0.00057 20.3 0.1 0.0011 19.4 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 AJZ76032.1 - 0.005 16.7 0.3 0.0095 15.9 0.3 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AJZ76032.1 - 0.017 15.1 0.6 0.045 13.7 0.6 1.7 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain DUF4364 PF14277.6 AJZ76032.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) Replic_Relax PF13814.6 AJZ76032.1 - 0.025 14.6 0.1 0.037 14.1 0.1 1.2 1 0 0 1 1 1 0 Replication-relaxation HTH_45 PF14947.6 AJZ76032.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix Penicillinase_R PF03965.16 AJZ76032.1 - 0.084 13.2 0.9 0.12 12.8 0.1 1.7 2 0 0 2 2 2 0 Penicillinase repressor Crp PF00325.20 AJZ76032.1 - 0.39 10.4 2.3 1.1 8.9 0.8 2.2 1 1 1 2 2 2 0 Bacterial regulatory proteins, crp family MazE_antitoxin PF04014.18 AJZ76033.1 - 1.2e-07 31.5 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin eIF-1a PF01176.19 AJZ76033.1 - 0.0012 18.6 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Xrn1_D3 PF18194.1 AJZ76033.1 - 0.017 15.2 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Exoribonuclease 1 Domain-3 CDC48_N PF02359.18 AJZ76033.1 - 0.067 13.4 0.0 0.09 13.0 0.0 1.3 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Penicillinase_R PF03965.16 AJZ76034.1 - 0.0045 17.3 0.0 0.0061 16.9 0.0 1.2 1 0 0 1 1 1 1 Penicillinase repressor Cdc6_C PF09079.11 AJZ76035.1 - 9.2e-16 57.6 0.1 2.5e-15 56.2 0.1 1.8 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 AJZ76035.1 - 3.8e-13 49.9 0.4 8.1e-13 48.8 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 AJZ76035.1 - 7.6e-12 45.8 0.7 2.9e-11 43.9 0.2 2.3 2 1 1 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AJZ76035.1 - 2.7e-11 44.2 0.3 1.4e-10 41.8 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 AJZ76035.1 - 2.6e-08 33.5 0.2 4.9e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 AJZ76035.1 - 4.7e-07 29.9 0.1 1.2e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 AJZ76035.1 - 7.7e-07 29.3 4.0 4.5e-06 26.7 2.6 2.6 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 AJZ76035.1 - 1.7e-06 27.5 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 AJZ76035.1 - 4.3e-05 22.8 0.1 0.00013 21.2 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.6 AJZ76035.1 - 0.0002 21.7 0.2 0.0017 18.7 0.2 2.4 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 AJZ76035.1 - 0.00026 20.4 0.4 0.13 11.5 0.0 2.3 2 0 0 2 2 2 2 KAP family P-loop domain AAA_32 PF13654.6 AJZ76035.1 - 0.0006 18.7 2.2 0.17 10.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain DUF815 PF05673.13 AJZ76035.1 - 0.00072 18.8 0.2 0.0033 16.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 AJZ76035.1 - 0.00098 18.7 0.0 0.0038 16.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 AJZ76035.1 - 0.0012 18.8 0.4 0.0095 15.9 0.4 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AJZ76035.1 - 0.0017 18.7 0.0 0.0044 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase PIF1 PF05970.14 AJZ76035.1 - 0.0024 17.1 0.0 0.0053 16.0 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase Sigma54_activat PF00158.26 AJZ76035.1 - 0.0031 17.2 0.0 0.0081 15.9 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain ATPase PF06745.13 AJZ76035.1 - 0.0068 15.8 0.6 0.27 10.5 0.0 3.1 2 1 1 3 3 3 1 KaiC AAA_30 PF13604.6 AJZ76035.1 - 0.0069 16.1 0.9 0.29 10.8 0.0 3.4 3 2 0 3 3 3 1 AAA domain AAA_11 PF13086.6 AJZ76035.1 - 0.011 15.5 3.2 0.039 13.8 3.2 2.1 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 AJZ76035.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_assoc_2 PF16193.5 AJZ76035.1 - 0.014 15.7 0.7 0.046 14.1 0.7 1.9 1 0 0 1 1 1 0 AAA C-terminal domain Zeta_toxin PF06414.12 AJZ76035.1 - 0.014 14.7 0.1 0.06 12.6 0.1 2.0 1 1 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 AJZ76035.1 - 0.016 14.9 0.9 0.092 12.5 0.9 2.2 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 AJZ76035.1 - 0.016 15.1 0.6 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 AJZ76035.1 - 0.018 14.4 0.0 0.056 12.8 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.9 AJZ76035.1 - 0.025 13.5 0.1 0.078 11.9 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_3 PF07726.11 AJZ76035.1 - 0.043 13.7 0.1 0.76 9.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AJZ76035.1 - 0.062 13.2 1.0 0.27 11.1 0.2 2.0 1 1 0 2 2 2 0 Rad17 P-loop domain Phage-MuB_C PF09077.11 AJZ76035.1 - 0.068 13.1 1.7 0.14 12.1 0.3 2.1 2 0 0 2 2 2 0 Mu B transposition protein, C terminal UvrD-helicase PF00580.21 AJZ76035.1 - 0.1 12.1 2.0 0.23 10.9 0.0 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Mg_chelatase_C PF13335.6 AJZ76035.1 - 0.13 12.9 4.1 0.15 12.7 1.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal DNA_pol_E_B PF04042.16 AJZ76036.1 - 9.3e-23 80.7 0.0 1.8e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos PF00149.28 AJZ76036.1 - 4.8e-12 46.8 0.1 9.4e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AJZ76036.1 - 1.7e-05 25.1 0.0 4.4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain tRNA_anti-codon PF01336.25 AJZ76036.1 - 0.0057 16.6 0.2 0.011 15.7 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DKNYY PF13644.6 AJZ76036.1 - 0.12 13.2 0.0 0.55 11.0 0.0 2.0 1 1 0 1 1 1 0 DKNYY family DNA_pol_D_N PF18018.1 AJZ76036.1 - 1.5 8.9 5.2 1.5 8.9 0.0 2.8 1 1 2 3 3 3 0 DNA polymerase delta subunit OB-fold domain SpoIIM PF01944.17 AJZ76037.1 - 2.5e-10 40.6 17.5 3.2e-10 40.2 17.5 1.0 1 0 0 1 1 1 1 Stage II sporulation protein M Copper-bind PF00127.20 AJZ76038.1 - 0.0012 19.2 0.0 0.0033 17.9 0.0 1.7 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family YcgR_2 PF12945.7 AJZ76038.1 - 0.049 13.8 0.0 4.3 7.5 0.0 2.9 2 0 0 2 2 2 0 Flagellar protein YcgR DUF1410 PF07198.11 AJZ76038.1 - 0.6 10.6 0.1 0.6 10.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1410) TP_methylase PF00590.20 AJZ76039.1 - 5.6e-31 108.1 0.0 6.3e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases GcpE PF04551.14 AJZ76039.1 - 0.029 13.5 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 GcpE protein FtsX_ECD PF18075.1 AJZ76039.1 - 0.072 13.7 0.1 0.17 12.5 0.1 1.6 1 0 0 1 1 1 0 FtsX extracellular domain MecA_N PF05223.11 AJZ76039.1 - 0.082 13.2 1.3 5 7.4 0.3 2.7 2 1 1 3 3 3 0 NTF2-like N-terminal transpeptidase domain DoxX PF07681.12 AJZ76041.1 - 1.5e-14 54.3 6.7 2.2e-14 53.8 6.7 1.3 1 0 0 1 1 1 1 DoxX DoxD PF04173.13 AJZ76041.1 - 5e-07 29.8 1.9 7.4e-06 26.0 1.1 2.0 2 0 0 2 2 2 1 TQO small subunit DoxD DoxX_2 PF13564.6 AJZ76041.1 - 5.6e-06 26.4 6.0 7.5e-06 26.0 6.0 1.3 1 1 0 1 1 1 1 DoxX-like family Peptidase_M24 PF00557.24 AJZ76042.1 - 9.5e-57 192.1 0.0 1.2e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 AJZ76042.1 - 1.1e-12 48.7 0.0 2.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain NFACT-R_2 PF18297.1 AJZ76043.1 - 1.6e-22 79.6 0.0 2.7e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain ThiI PF02568.14 AJZ76043.1 - 7.5e-12 45.2 0.0 1.8e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 AJZ76043.1 - 8.1e-10 38.0 0.0 2.4e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 AJZ76043.1 - 0.0039 16.7 0.1 0.0077 15.7 0.1 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NFACT-R_1 PF05670.13 AJZ76043.1 - 0.012 16.2 0.0 0.029 15.0 0.0 1.6 1 0 0 1 1 1 0 NFACT protein RNA binding domain Asn_synthase PF00733.21 AJZ76043.1 - 0.034 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase SepF PF04472.12 AJZ76044.1 - 2.3e-11 43.8 0.2 2.6e-11 43.6 0.2 1.0 1 0 0 1 1 1 1 Cell division protein SepF CcmE PF03100.15 AJZ76045.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 CcmE PYNP_C PF07831.13 AJZ76045.1 - 0.15 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF1857 PF08982.11 AJZ76046.1 - 1.1e-08 35.0 0.0 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) LolA_2 PF16584.5 AJZ76046.1 - 0.035 14.0 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Polyketide_cyc2 PF10604.9 AJZ76046.1 - 0.044 14.1 0.0 0.044 14.1 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Pirin PF02678.16 AJZ76047.1 - 1.9e-33 114.7 1.1 3.3e-33 113.9 1.1 1.3 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 AJZ76047.1 - 1.4e-17 63.6 0.1 3.1e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 AJZ76047.1 - 1.2e-05 24.9 2.7 5.3e-05 22.8 0.1 2.7 3 0 0 3 3 3 1 Cupin domain Pox_A31 PF05771.11 AJZ76047.1 - 0.014 15.4 0.8 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A31 protein Peptidase_M48 PF01435.18 AJZ76048.1 - 1.3e-40 139.3 0.2 1.3e-40 139.3 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 AJZ76048.1 - 3.4e-05 23.2 0.2 7.1e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 BlaR1 peptidase M56 SprT-like PF10263.9 AJZ76048.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 SprT-like family DUF2975 PF11188.8 AJZ76048.1 - 8.3 6.3 9.1 18 5.2 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Phage_holin_3_6 PF07332.11 AJZ76048.1 - 9.7 6.3 8.0 5.4 7.1 2.7 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Beta-Casp PF10996.8 AJZ76049.1 - 6.5e-23 81.1 0.0 1.3e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain KH_7 PF17214.3 AJZ76049.1 - 9.2e-22 76.8 0.8 4.7e-20 71.3 0.3 3.3 3 0 0 3 3 3 1 KH domain RMMBL PF07521.12 AJZ76049.1 - 3.3e-16 59.0 0.0 7.4e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 AJZ76049.1 - 4e-13 49.8 0.4 8.7e-12 45.5 0.2 2.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 AJZ76049.1 - 1.3e-12 47.5 0.0 3.2e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 AJZ76049.1 - 3.5e-10 39.8 0.0 8.2e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AJZ76049.1 - 0.066 13.1 0.2 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Metallophos PF00149.28 AJZ76051.1 - 2.5e-13 51.0 0.5 5e-13 50.0 0.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AJZ76051.1 - 3.1e-12 47.0 0.0 5.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain adh_short PF00106.25 AJZ76052.1 - 1.1e-20 73.9 0.0 3.8e-13 49.3 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 AJZ76052.1 - 1.4e-20 73.9 0.0 8.4e-17 61.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 AJZ76052.1 - 2.7e-06 26.7 0.1 4.8e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.21 AJZ76052.1 - 0.0035 16.8 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 AJZ76052.1 - 0.04 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hemerythrin PF01814.23 AJZ76053.1 - 7.4e-11 42.8 1.6 3.3e-08 34.2 0.0 1.6 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain ORF11CD3 PF10549.9 AJZ76053.1 - 0.031 14.4 2.0 0.25 11.5 0.1 2.5 2 0 0 2 2 2 0 ORF11CD3 domain tRNA_NucTran2_2 PF13735.6 AJZ76053.1 - 0.039 13.9 1.2 0.1 12.6 1.2 1.8 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative DUF445 PF04286.12 AJZ76053.1 - 0.04 13.7 1.0 0.043 13.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Inositol_P PF00459.25 AJZ76054.1 - 2.8e-46 158.3 0.1 3.2e-46 158.0 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AJZ76054.1 - 0.0016 17.9 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Yqai PF09466.10 AJZ76054.1 - 0.038 14.3 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 Hypothetical protein Yqai EMP70 PF02990.16 AJZ76055.1 - 4.2 5.9 5.7 23 3.5 5.7 1.9 1 1 0 1 1 1 0 Endomembrane protein 70 adh_short_C2 PF13561.6 AJZ76056.1 - 3.7e-65 219.7 0.1 4.6e-65 219.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AJZ76056.1 - 1.3e-56 191.2 0.1 1.5e-56 190.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AJZ76056.1 - 4.7e-08 33.1 0.1 7.3e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AJZ76056.1 - 0.00055 19.5 0.3 0.0087 15.5 0.0 2.5 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 AJZ76056.1 - 0.041 14.5 1.1 0.13 12.8 0.5 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 AJZ76056.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TFIIB PF00382.19 AJZ76057.1 - 2.5e-33 114.0 2.5 7.3e-16 58.0 0.8 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJZ76057.1 - 8.8e-06 25.1 1.4 1.7e-05 24.2 1.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 AJZ76057.1 - 5.7e-05 23.2 0.0 0.027 14.6 0.0 2.2 2 0 0 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 AJZ76057.1 - 0.00041 19.8 0.0 0.01 15.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_11 PF08279.12 AJZ76057.1 - 0.0033 17.4 0.8 0.16 12.0 0.0 3.0 3 0 0 3 3 3 1 HTH domain Cyclin_N PF00134.23 AJZ76057.1 - 0.0094 15.7 0.1 0.057 13.2 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain HTH_AsnC-type PF13404.6 AJZ76057.1 - 0.02 14.7 0.0 0.21 11.4 0.0 2.6 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 AJZ76057.1 - 0.031 14.0 0.2 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 AJZ76057.1 - 0.038 13.4 0.2 0.48 9.9 0.0 2.8 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 AJZ76057.1 - 0.042 13.7 0.0 0.18 11.7 0.0 2.1 1 0 0 1 1 1 0 Homeodomain-like domain Rrf2 PF02082.20 AJZ76057.1 - 0.084 13.2 0.3 17 5.8 0.1 3.1 1 1 2 3 3 3 0 Transcriptional regulator Phage_terminase PF10668.9 AJZ76057.1 - 0.088 12.8 0.1 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 Phage terminase small subunit HTH_3 PF01381.22 AJZ76057.1 - 0.12 12.5 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix OrfB_Zn_ribbon PF07282.11 AJZ76057.1 - 0.15 12.0 1.2 0.34 10.9 1.2 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-CCHC_5 PF14787.6 AJZ76057.1 - 0.17 11.6 0.8 0.37 10.5 0.3 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Snf7 PF03357.21 AJZ76058.1 - 0.00035 20.2 2.5 0.00053 19.6 2.5 1.3 1 1 0 1 1 1 1 Snf7 YjcZ PF13990.6 AJZ76058.1 - 0.0009 18.7 0.6 0.0015 18.0 0.5 1.5 1 1 0 1 1 1 1 YjcZ-like protein PriC PF07445.12 AJZ76058.1 - 0.011 15.7 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 0 Primosomal replication protein priC SHE3 PF17078.5 AJZ76058.1 - 0.02 14.6 1.1 0.031 14.0 1.1 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 HMMR_C PF15908.5 AJZ76058.1 - 0.025 14.9 1.0 0.044 14.0 0.8 1.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DivIVA PF05103.13 AJZ76058.1 - 0.025 14.7 0.6 0.19 11.8 0.3 2.2 2 0 0 2 2 2 0 DivIVA protein DUF3251 PF11622.8 AJZ76058.1 - 0.029 14.0 0.8 0.057 13.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) LOH1CR12 PF10158.9 AJZ76058.1 - 0.031 14.3 0.2 0.071 13.1 0.2 1.6 1 0 0 1 1 1 0 Tumour suppressor protein DASH_Spc19 PF08287.11 AJZ76058.1 - 0.032 14.1 0.9 0.061 13.2 0.9 1.4 1 0 0 1 1 1 0 Spc19 Serine_rich PF08824.10 AJZ76058.1 - 0.062 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain Rx_N PF18052.1 AJZ76058.1 - 0.085 13.1 0.9 0.65 10.3 0.2 2.3 1 1 1 2 2 2 0 Rx N-terminal domain STAT_alpha PF01017.20 AJZ76058.1 - 0.13 12.2 1.9 0.17 11.8 1.9 1.3 1 1 0 1 1 1 0 STAT protein, all-alpha domain TPR_10 PF13374.6 AJZ76058.1 - 0.13 12.2 0.7 0.32 10.9 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Spc7 PF08317.11 AJZ76059.1 - 0.00029 19.8 4.7 0.00029 19.8 4.7 1.4 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 AJZ76059.1 - 0.00054 20.0 3.8 0.00082 19.4 3.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) DHR10 PF18595.1 AJZ76059.1 - 0.0012 18.9 2.0 0.0012 18.9 2.0 1.7 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain CREPT PF16566.5 AJZ76059.1 - 0.0032 17.7 1.5 0.0038 17.4 1.5 1.3 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour DUF724 PF05266.14 AJZ76059.1 - 0.0048 16.7 3.7 0.0048 16.7 3.7 1.7 1 1 1 2 2 2 2 Protein of unknown function (DUF724) HMMR_N PF15905.5 AJZ76059.1 - 0.0054 16.3 6.0 0.0054 16.3 6.0 1.8 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal KASH_CCD PF14662.6 AJZ76059.1 - 0.0054 16.6 2.0 0.0054 16.6 2.0 1.8 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH YlbD_coat PF14071.6 AJZ76059.1 - 0.074 13.3 3.6 0.59 10.4 0.5 2.5 1 1 2 3 3 3 0 Putative coat protein Tropomyosin_1 PF12718.7 AJZ76059.1 - 0.077 13.2 11.6 0.52 10.5 11.6 2.5 1 1 0 1 1 1 0 Tropomyosin like DUF3450 PF11932.8 AJZ76059.1 - 0.097 12.0 3.7 0.051 12.9 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Mei5 PF10376.9 AJZ76059.1 - 0.098 12.5 7.7 0.25 11.2 7.6 1.9 1 1 0 1 1 1 0 Double-strand recombination repair protein UPF0242 PF06785.11 AJZ76059.1 - 0.24 11.5 6.7 0.3 11.2 6.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin_2 PF14523.6 AJZ76059.1 - 0.29 11.5 4.6 6.6 7.2 2.2 2.7 1 1 1 2 2 2 0 Syntaxin-like protein TMEM192 PF14802.6 AJZ76059.1 - 0.45 9.6 1.8 6.7 5.7 0.1 2.1 2 0 0 2 2 2 0 TMEM192 family DUF16 PF01519.16 AJZ76059.1 - 0.53 10.8 5.0 2.6 8.6 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 AJZ76059.1 - 0.71 10.4 3.9 4.5 7.8 1.7 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 AJZ76059.1 - 1.4 9.6 5.8 2.8 8.6 0.4 2.8 2 1 1 3 3 3 0 SlyX FAM76 PF16046.5 AJZ76059.1 - 2.3 7.5 5.9 2.7 7.2 5.9 1.1 1 0 0 1 1 1 0 FAM76 protein Fib_alpha PF08702.10 AJZ76059.1 - 3 8.0 6.0 3.6 7.7 2.2 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-H PF05837.12 AJZ76059.1 - 3.4 8.1 8.4 0.67 10.4 3.8 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4200 PF13863.6 AJZ76059.1 - 3.5 8.0 11.8 0.45 10.9 4.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) YabA PF06156.13 AJZ76059.1 - 4.1 8.1 7.8 0.61 10.7 2.1 2.2 2 1 1 3 3 2 0 Initiation control protein YabA CortBP2 PF09727.9 AJZ76059.1 - 4.3 7.2 10.8 0.95 9.3 3.2 2.7 1 1 2 3 3 3 0 Cortactin-binding protein-2 Atg14 PF10186.9 AJZ76059.1 - 8.1 5.4 8.5 26 3.8 8.5 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RST PF12174.8 AJZ76060.1 - 0.075 13.0 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain AIRS_C PF02769.22 AJZ76060.1 - 0.11 12.6 1.0 0.2 11.7 0.1 1.9 2 0 0 2 2 2 0 AIR synthase related protein, C-terminal domain DUF732 PF05305.14 AJZ76060.1 - 2.8 8.4 5.8 0.73 10.2 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF732) DUF2096 PF09869.9 AJZ76060.1 - 4.3 7.4 10.0 3.1 7.8 0.0 3.6 2 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2096) Neur_chan_memb PF02932.16 AJZ76060.1 - 6.5 6.7 10.7 0.21 11.6 3.6 2.0 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SKG6 PF08693.10 AJZ76061.1 - 0.25 10.8 0.1 0.25 10.8 0.1 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain MGC-24 PF05283.11 AJZ76061.1 - 0.3 11.5 0.3 0.34 11.3 0.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Fer4_12 PF13353.6 AJZ76062.1 - 4.3e-12 46.5 0.4 1.1e-11 45.1 0.1 1.7 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AJZ76062.1 - 4.5e-11 42.9 0.6 9e-11 42.0 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 AJZ76062.1 - 1.9e-10 41.4 0.0 3e-10 40.7 0.0 1.3 1 1 0 1 1 1 1 Radical SAM superfamily Trm5_N PF18093.1 AJZ76062.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain GTP_cyclohydroI PF01227.22 AJZ76063.1 - 1e-63 214.0 0.0 1.2e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 AJZ76063.1 - 0.011 15.8 0.0 0.046 13.9 0.0 2.0 2 0 0 2 2 2 0 QueF-like protein AAA_22 PF13401.6 AJZ76063.1 - 0.13 12.5 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain FeoB_C PF07664.12 AJZ76064.1 - 0.036 13.8 0.8 0.39 10.4 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus QueC PF06508.13 AJZ76065.1 - 5.3e-47 160.0 0.1 6.2e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AJZ76065.1 - 0.00061 19.6 0.0 0.00086 19.1 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GHMP_kinases_N PF00288.26 AJZ76066.1 - 3.7e-13 49.5 3.2 8.9e-13 48.3 3.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AJZ76066.1 - 3.8e-09 36.8 0.1 9.9e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal ATP_bind_1 PF03029.17 AJZ76067.1 - 6.8e-55 186.5 0.0 7.6e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein DUF2075 PF09848.9 AJZ76067.1 - 0.0033 16.7 0.1 0.005 16.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 AJZ76067.1 - 0.0039 17.6 0.0 0.012 16.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 AJZ76067.1 - 0.0081 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 AJZ76067.1 - 0.0084 15.1 0.0 0.02 13.9 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 AJZ76067.1 - 0.022 14.0 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 AJZ76067.1 - 0.022 14.4 0.1 1 9.0 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 AJZ76067.1 - 0.04 13.7 0.1 0.071 12.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AJZ76067.1 - 0.066 13.1 0.4 17 5.3 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase NACHT PF05729.12 AJZ76067.1 - 0.073 13.0 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 AJZ76067.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 AJZ76067.1 - 0.084 13.4 0.0 0.17 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AJZ76067.1 - 0.093 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 AJZ76067.1 - 0.12 12.2 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 AJZ76067.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain LPG_synthase_TM PF03706.13 AJZ76068.1 - 6.2e-20 71.9 16.9 9.4e-20 71.3 16.8 1.4 1 1 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region p450 PF00067.22 AJZ76068.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 adh_short PF00106.25 AJZ76069.1 - 2.8e-58 196.6 0.5 3.5e-58 196.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AJZ76069.1 - 3.5e-43 147.8 0.0 4.3e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJZ76069.1 - 2.7e-18 66.5 0.2 3.6e-18 66.1 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AJZ76069.1 - 1e-07 31.7 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.15 AJZ76069.1 - 0.00086 19.2 0.2 0.0016 18.3 0.2 1.5 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Sacchrp_dh_NADP PF03435.18 AJZ76069.1 - 0.0014 18.9 0.1 0.0021 18.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 AJZ76069.1 - 0.0021 17.2 0.2 0.0026 16.9 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AJZ76069.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 AJZ76069.1 - 0.038 13.3 0.1 0.07 12.4 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ribosomal_L32p PF01783.23 AJZ76070.1 - 0.0022 18.2 0.5 0.27 11.5 0.0 2.3 2 0 0 2 2 2 2 Ribosomal L32p protein family CARD_2 PF16739.5 AJZ76070.1 - 0.024 14.6 0.1 0.064 13.2 0.1 1.6 2 0 0 2 2 2 0 Caspase recruitment domain TF_Zn_Ribbon PF08271.12 AJZ76070.1 - 0.05 13.1 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_12 PF18658.1 AJZ76070.1 - 0.053 13.1 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger C2H2-type Rpr2 PF04032.16 AJZ76070.1 - 0.077 13.3 0.3 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Glyco_trans_1_3 PF13528.6 AJZ76071.1 - 0.00023 20.5 0.0 0.17 11.1 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 1 Tautomerase_2 PF14552.6 AJZ76072.1 - 0.026 14.6 0.6 0.13 12.4 0.1 2.2 2 0 0 2 2 2 0 Tautomerase enzyme PAPS_reduct PF01507.19 AJZ76073.1 - 8.8e-45 152.9 0.0 1.2e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Lipase_GDSL_lke PF16255.5 AJZ76073.1 - 0.025 13.9 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase ATP-sulfurylase PF01747.17 AJZ76074.1 - 5.3e-81 271.1 0.0 6.9e-81 270.8 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 AJZ76074.1 - 3.3e-43 147.1 0.0 6.3e-43 146.2 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain S-l_SbsC_C PF18316.1 AJZ76075.1 - 0.088 13.3 0.3 0.25 11.9 0.2 1.8 2 0 0 2 2 2 0 S-layer protein SbsC C-terminal domain DUF4781 PF16013.5 AJZ76075.1 - 0.24 10.1 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Gram_pos_anchor PF00746.21 AJZ76075.1 - 0.37 10.8 1.4 0.82 9.7 1.4 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF521 PF04412.13 AJZ76076.1 - 3.5e-110 368.4 0.0 4.2e-110 368.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.16 AJZ76077.1 - 1.1e-26 92.4 0.1 1.7e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 Aconitase X swivel domain DUF3945 PF13101.6 AJZ76077.1 - 0.099 12.4 0.0 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) AMMECR1 PF01871.17 AJZ76078.1 - 3.9e-50 169.7 0.0 4.5e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Mut7-C PF01927.16 AJZ76079.1 - 7.9e-36 123.4 0.0 8.9e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain DUF5615 PF18480.1 AJZ76079.1 - 0.0013 18.4 0.3 0.0025 17.5 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5615) FbpA PF05833.11 AJZ76080.1 - 2.1e-47 162.0 1.5 2.7e-47 161.6 1.5 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 AJZ76080.1 - 1.2e-20 74.2 0.0 4.1e-20 72.4 0.0 2.0 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF3236 PF11576.8 AJZ76080.1 - 0.025 14.3 0.4 0.025 14.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) Myotub-related PF06602.14 AJZ76080.1 - 0.051 12.5 0.4 2.3 7.0 0.1 2.1 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain KASH_CCD PF14662.6 AJZ76080.1 - 0.79 9.5 5.9 5.9 6.7 1.0 2.6 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH PHM7_cyt PF14703.6 AJZ76080.1 - 1.8 8.8 7.3 8.6 6.6 7.3 2.0 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF5379 PF17350.2 AJZ76081.1 - 0.0011 19.2 6.3 0.0024 18.1 6.3 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5379) Multi_Drug_Res PF00893.19 AJZ76081.1 - 0.0034 18.0 3.3 0.082 13.6 2.5 2.0 1 1 1 2 2 2 1 Small Multidrug Resistance protein NrsF PF06532.11 AJZ76081.1 - 0.035 13.8 0.1 0.045 13.5 0.1 1.3 1 1 0 1 1 1 0 Negative regulator of sigma F CPP1-like PF11833.8 AJZ76081.1 - 0.12 12.0 0.7 0.13 11.9 0.7 1.3 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF543 PF04418.12 AJZ76081.1 - 0.14 12.2 0.2 0.37 10.8 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF543) Rab5ip PF07019.12 AJZ76081.1 - 0.4 11.3 5.0 0.72 10.5 5.0 1.4 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DUF202 PF02656.15 AJZ76081.1 - 5 7.6 6.5 25 5.4 6.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Methyltransf_31 PF13847.6 AJZ76082.1 - 3.3e-12 46.4 0.1 6.6e-12 45.5 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AJZ76082.1 - 8.9e-11 41.9 0.3 1.1e-10 41.6 0.3 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 AJZ76082.1 - 1.5e-09 38.0 0.6 2.2e-09 37.4 0.6 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJZ76082.1 - 2.5e-08 34.5 0.0 4.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AJZ76082.1 - 3.3e-08 33.3 1.5 4.4e-08 32.9 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 AJZ76082.1 - 2.3e-07 30.4 0.1 3e-07 30.0 0.1 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 AJZ76082.1 - 3.6e-07 30.7 0.0 1.1e-06 29.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AJZ76082.1 - 2.5e-06 27.1 0.0 4.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.17 AJZ76082.1 - 3.7e-06 26.3 0.1 6.4e-06 25.5 0.0 1.3 2 0 0 2 2 2 1 O-methyltransferase Met_10 PF02475.16 AJZ76082.1 - 5.5e-06 26.3 0.0 6.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.17 AJZ76082.1 - 3.4e-05 23.4 0.0 7.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltr_RsmB-F PF01189.17 AJZ76082.1 - 5e-05 23.0 0.1 0.00031 20.4 0.0 2.0 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_12 PF08242.12 AJZ76082.1 - 5.7e-05 23.8 0.1 0.00012 22.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AJZ76082.1 - 0.00061 19.5 0.0 0.00093 18.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 AJZ76082.1 - 0.0013 18.4 0.1 0.0023 17.5 0.1 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase AviRa PF11599.8 AJZ76082.1 - 0.0014 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_24 PF13578.6 AJZ76082.1 - 0.002 19.1 0.0 0.0029 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 AJZ76082.1 - 0.003 17.3 0.2 0.035 13.8 0.2 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.20 AJZ76082.1 - 0.0059 15.9 0.0 0.014 14.7 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 AJZ76082.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_23 PF13489.6 AJZ76082.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 AJZ76082.1 - 0.059 12.9 0.0 0.097 12.2 0.0 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 Spermine_synth PF01564.17 AJZ76082.1 - 0.086 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Methyltransf_32 PF13679.6 AJZ76082.1 - 0.09 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NAC PF01849.18 AJZ76082.1 - 0.12 12.3 0.1 1.4 8.9 0.0 2.5 3 0 0 3 3 3 0 NAC domain TP_methylase PF00590.20 AJZ76083.1 - 4.4e-54 183.7 0.0 4.9e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TP_methylase PF00590.20 AJZ76084.1 - 2.4e-46 158.4 0.1 2.8e-46 158.1 0.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases UvrA_inter PF17760.1 AJZ76084.1 - 0.025 14.6 0.1 0.51 10.4 0.0 2.8 3 0 0 3 3 3 0 UvrA interaction domain UPF0180 PF03698.13 AJZ76084.1 - 0.12 12.5 0.3 0.43 10.8 0.0 2.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) LPD14 PF18827.1 AJZ76084.1 - 0.15 12.4 0.0 0.47 10.7 0.0 1.8 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 14 MutS_IV PF05190.18 AJZ76086.1 - 0.12 12.7 0.1 0.29 11.5 0.0 1.6 2 0 0 2 2 2 0 MutS family domain IV KASH_CCD PF14662.6 AJZ76087.1 - 0.00053 19.9 2.4 0.00099 19.0 2.4 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH BLOC1S3 PF15753.5 AJZ76087.1 - 0.0014 18.8 0.9 0.0014 18.8 0.9 1.9 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 Cas_Cas7 PF05107.12 AJZ76087.1 - 0.013 15.1 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cas7 Snf7 PF03357.21 AJZ76087.1 - 0.013 15.1 8.0 0.035 13.7 8.0 1.7 1 1 0 1 1 1 0 Snf7 ATG16 PF08614.11 AJZ76087.1 - 0.025 14.8 0.9 0.025 14.8 0.9 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TipAS PF07739.13 AJZ76087.1 - 0.048 14.2 0.8 2.9 8.4 0.7 2.5 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Collagen_mid PF15984.5 AJZ76087.1 - 0.056 13.2 0.2 1 9.1 0.0 2.0 1 1 1 2 2 2 0 Bacterial collagen, middle region Serine_rich PF08824.10 AJZ76087.1 - 0.06 13.3 2.9 0.12 12.3 3.0 1.4 1 1 0 1 1 1 0 Serine rich protein interaction domain AAA_6 PF12774.7 AJZ76087.1 - 0.07 12.1 0.6 0.12 11.4 0.6 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region NMT1_3 PF16868.5 AJZ76087.1 - 0.083 12.3 0.2 0.58 9.5 0.1 2.0 1 1 1 2 2 2 0 NMT1-like family Prominin PF05478.11 AJZ76087.1 - 0.097 10.6 2.0 2.2 6.1 1.4 2.0 1 1 1 2 2 2 0 Prominin Rx_N PF18052.1 AJZ76087.1 - 0.19 12.0 1.6 1 9.6 0.4 2.4 1 1 1 2 2 2 0 Rx N-terminal domain DASH_Dad4 PF08650.10 AJZ76087.1 - 0.23 11.5 1.7 5.9 6.9 0.2 2.3 1 1 1 2 2 2 0 DASH complex subunit Dad4 DASH_Duo1 PF08651.10 AJZ76087.1 - 0.24 11.2 2.6 0.79 9.5 0.1 2.6 3 0 0 3 3 3 0 DASH complex subunit Duo1 Asp_Glu_race PF01177.22 AJZ76088.1 - 7.4e-15 55.4 0.0 8.9e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Laminin_G_3 PF13385.6 AJZ76089.1 - 2.4e-24 86.2 13.6 1.2e-14 54.7 7.5 6.7 7 2 0 7 7 7 2 Concanavalin A-like lectin/glucanases superfamily FpoO PF10621.9 AJZ76089.1 - 0.28 11.5 0.6 38 4.6 0.0 2.6 2 0 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO Cdh1_DBD_1 PF18196.1 AJZ76089.1 - 1 9.7 5.2 2.7 8.4 5.2 1.6 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 HHH_2 PF12826.7 AJZ76090.1 - 0.034 14.2 0.2 25 5.0 0.0 6.1 2 1 0 1 1 1 0 Helix-hairpin-helix motif Spore_YunB PF09560.10 AJZ76090.1 - 0.56 10.2 3.7 0.36 10.9 0.1 2.4 2 0 0 2 2 2 0 Sporulation protein YunB (Spo_YunB) HGTP_anticodon PF03129.20 AJZ76091.1 - 1.5e-14 53.9 0.3 6.2e-14 51.9 0.2 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AJZ76091.1 - 1.5e-11 44.6 0.1 1e-10 41.9 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Zn-ribbon_8 PF09723.10 AJZ76091.1 - 0.053 13.6 0.2 3.6 7.8 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain AP_endonuc_2 PF01261.24 AJZ76092.1 - 9.5e-34 116.7 0.0 3.7e-33 114.7 0.0 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF4621 PF15414.6 AJZ76092.1 - 0.071 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) DNA_primase_lrg PF04104.14 AJZ76093.1 - 2.2e-24 86.3 0.1 4.6e-24 85.2 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Med5 PF08689.10 AJZ76093.1 - 0.0098 13.8 1.7 0.012 13.4 1.7 1.1 1 0 0 1 1 1 1 Mediator complex subunit Med5 DNA_primase_S PF01896.19 AJZ76094.1 - 1.2e-12 48.3 1.1 3.8e-12 46.6 0.1 2.0 2 0 0 2 2 2 1 DNA primase small subunit TackOD1 PF18551.1 AJZ76094.1 - 0.008 15.9 2.7 0.014 15.1 2.7 1.4 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 MutS_IV PF05190.18 AJZ76094.1 - 0.085 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 MutS family domain IV HypA PF01155.19 AJZ76094.1 - 1.4 8.9 8.2 2.3 8.3 6.3 2.4 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UPF0182 PF03699.13 AJZ76095.1 - 7.6e-36 123.6 9.1 4.5e-35 121.0 9.1 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0182) GATase PF00117.28 AJZ76096.1 - 1.6e-22 80.2 0.1 1.9e-22 79.9 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJZ76096.1 - 9.3e-11 41.9 0.0 4.8e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AJZ76096.1 - 0.028 14.3 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 SNO glutamine amidotransferase family DJ-1_PfpI PF01965.24 AJZ76096.1 - 0.055 13.3 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 DJ-1/PfpI family GATase_3 PF07685.14 AJZ76096.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain TPR_1 PF00515.28 AJZ76097.1 - 5.4e-14 51.3 8.8 2.9e-06 26.8 0.7 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 AJZ76097.1 - 2.8e-12 45.7 6.0 0.00043 20.2 0.3 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 AJZ76097.1 - 5.9e-09 35.4 9.2 0.0081 16.3 0.4 5.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 AJZ76097.1 - 1.6e-07 31.2 6.0 0.0003 21.0 0.5 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 AJZ76097.1 - 3.8e-07 29.7 7.7 0.00012 21.6 0.1 3.9 2 1 2 4 4 4 2 TPR repeat TPR_12 PF13424.6 AJZ76097.1 - 1.5e-06 28.3 1.0 0.003 17.8 0.2 3.4 1 1 1 3 3 3 2 Tetratricopeptide repeat Peptidase_C39_2 PF13529.6 AJZ76097.1 - 7.5e-06 26.6 0.2 5.2e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 Peptidase_C39 like family TPR_9 PF13371.6 AJZ76097.1 - 0.0002 21.4 0.0 0.0005 20.2 0.0 1.6 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 AJZ76097.1 - 0.00041 20.9 0.0 0.21 12.5 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 AJZ76097.1 - 0.00052 20.5 2.7 0.57 10.7 0.1 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AJZ76097.1 - 0.0015 19.2 0.0 0.29 11.8 0.0 2.9 1 1 0 2 2 2 1 Tetratricopeptide repeat Peptidase_C39 PF03412.15 AJZ76097.1 - 0.0039 17.0 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase C39 family TPR_10 PF13374.6 AJZ76097.1 - 0.024 14.5 1.5 1.9 8.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ATLF PF07737.11 AJZ76097.1 - 0.087 12.1 2.3 0.19 11.0 0.8 2.3 1 1 1 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain TPR_7 PF13176.6 AJZ76097.1 - 0.19 11.8 1.4 6.9 7.0 0.0 3.6 3 2 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 AJZ76097.1 - 1.9 8.6 6.0 91 3.2 0.1 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 AJZ76097.1 - 4.5 8.1 5.6 14 6.6 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_S6e PF01092.19 AJZ76098.1 - 8.4e-26 90.4 0.3 9.3e-26 90.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S6e GTP_EFTU PF00009.27 AJZ76099.1 - 1.7e-29 102.7 0.1 5.8e-29 101.0 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 AJZ76099.1 - 7.6e-24 83.8 0.1 2.3e-23 82.2 0.1 1.9 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal MMR_HSR1 PF01926.23 AJZ76099.1 - 2.5e-05 24.3 0.0 6.5e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AJZ76099.1 - 0.00023 21.5 0.5 0.00064 20.1 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 AJZ76099.1 - 0.00051 20.0 0.4 0.023 14.6 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 AJZ76099.1 - 0.044 13.3 0.4 2.2 7.8 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 AJZ76099.1 - 0.048 13.7 0.5 0.11 12.5 0.1 1.8 2 0 0 2 2 1 0 C-terminal region of MMR_HSR1 domain HypA PF01155.19 AJZ76099.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ProQ_C PF17516.2 AJZ76099.1 - 0.077 12.4 0.2 0.29 10.6 0.1 1.9 2 0 0 2 2 2 0 ProQ C-terminal domain Zn_Tnp_IS1595 PF12760.7 AJZ76099.1 - 0.084 12.9 0.7 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 AJZ76099.1 - 0.095 12.9 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like PhnA_Zn_Ribbon PF08274.12 AJZ76099.1 - 0.15 12.0 0.6 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.10 AJZ76099.1 - 3.1 8.0 4.7 9.4 6.5 4.7 1.8 1 1 0 1 1 1 0 Zinc ribbon domain PIN_9 PF18477.1 AJZ76100.1 - 1.4e-14 54.4 0.1 1.6e-14 54.2 0.1 1.0 1 0 0 1 1 1 1 PIN like domain Fcf1 PF04900.12 AJZ76100.1 - 0.00016 22.0 0.0 0.0002 21.7 0.0 1.2 1 0 0 1 1 1 1 Fcf1 PIN_12 PF16289.5 AJZ76100.1 - 0.0013 19.2 1.5 0.0017 18.9 1.5 1.2 1 0 0 1 1 1 1 PIN domain PIN_4 PF13638.6 AJZ76100.1 - 0.0042 17.4 0.4 0.0056 17.0 0.4 1.3 1 1 0 1 1 1 1 PIN domain DUF5615 PF18480.1 AJZ76100.1 - 0.0063 16.2 0.1 0.016 15.0 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF5615) PIN PF01850.21 AJZ76100.1 - 0.045 14.2 0.5 0.34 11.4 0.2 1.9 1 1 1 2 2 2 0 PIN domain PBP PF01161.20 AJZ76101.1 - 3e-35 121.4 0.0 3.5e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Phage_Cox PF10743.9 AJZ76101.1 - 0.066 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Regulatory phage protein cox EIF_2_alpha PF07541.12 AJZ76102.1 - 7.1e-19 68.0 0.1 1.5e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 AJZ76102.1 - 6.8e-09 36.0 0.0 1.4e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain SidE PF12252.8 AJZ76102.1 - 0.0028 15.3 1.7 0.003 15.2 1.7 1.1 1 0 0 1 1 1 1 Dot/Icm substrate protein EXOSC1 PF10447.9 AJZ76102.1 - 0.0081 16.8 0.2 0.034 14.8 0.1 2.2 1 1 1 2 2 2 1 Exosome component EXOSC1/CSL4 S1_2 PF13509.6 AJZ76102.1 - 0.014 15.5 0.3 0.14 12.2 0.0 2.5 3 0 0 3 3 3 0 S1 domain COG5 PF10392.9 AJZ76102.1 - 0.066 13.4 0.2 0.16 12.1 0.2 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 GATase_3 PF07685.14 AJZ76103.1 - 6e-42 143.5 0.1 8.7e-42 142.9 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AAA_26 PF13500.6 AJZ76103.1 - 2.1e-20 73.4 2.0 1.6e-13 50.9 0.0 2.7 2 1 1 3 3 3 2 AAA domain CbiA PF01656.23 AJZ76103.1 - 3.8e-17 62.5 0.1 9.5e-17 61.3 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SNO PF01174.19 AJZ76103.1 - 0.0066 16.3 0.0 0.018 14.9 0.0 1.7 1 1 1 2 2 2 1 SNO glutamine amidotransferase family Fer4_NifH PF00142.18 AJZ76103.1 - 0.065 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CTP_synth_N PF06418.14 AJZ76103.1 - 0.15 11.4 2.1 0.11 11.9 0.3 1.6 2 0 0 2 2 2 0 CTP synthase N-terminus CbiC PF02570.15 AJZ76104.1 - 7e-72 241.2 0.2 7.9e-72 241.0 0.2 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase CbiX PF01903.17 AJZ76105.1 - 2.3e-35 121.1 0.0 3.9e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 CbiX Ferrochelatase PF00762.19 AJZ76105.1 - 1e-05 24.8 0.3 0.0004 19.6 0.0 2.0 2 0 0 2 2 2 2 Ferrochelatase CBM77 PF18283.1 AJZ76105.1 - 0.0033 17.8 0.5 0.0067 16.8 0.5 1.5 1 0 0 1 1 1 1 Carbohydrate binding module 77 CbiD PF01888.17 AJZ76106.1 - 5.9e-91 304.2 7.7 8.8e-91 303.7 7.7 1.3 1 0 0 1 1 1 1 CbiD DUF3042 PF11240.8 AJZ76106.1 - 0.054 13.5 0.4 0.054 13.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) NAD_binding_10 PF13460.6 AJZ76107.1 - 1.4e-16 60.9 0.0 2.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AJZ76107.1 - 4.6e-13 49.2 0.0 5.3e-12 45.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 AJZ76107.1 - 2.1e-09 37.0 0.2 0.011 14.9 0.0 3.1 1 1 2 3 3 3 3 Male sterility protein 3Beta_HSD PF01073.19 AJZ76107.1 - 1.4e-08 34.1 1.1 1.2e-07 31.1 1.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 AJZ76107.1 - 1.9e-07 30.9 0.1 2.9e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 AJZ76107.1 - 7.4e-07 28.6 0.0 4.2e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AJZ76107.1 - 0.022 13.9 0.6 0.16 11.1 0.6 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 AJZ76107.1 - 0.029 13.8 0.1 0.055 12.8 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase S-AdoMet_synt_C PF02773.16 AJZ76108.1 - 3.3e-69 231.2 0.1 3.1e-68 228.0 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 AJZ76108.1 - 1.9e-49 166.9 0.1 2.4e-48 163.4 0.0 2.4 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 AJZ76108.1 - 1.3e-45 154.1 3.1 8.8e-45 151.4 0.2 2.5 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 AJZ76108.1 - 0.016 14.0 0.1 0.075 11.8 0.0 2.1 2 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) dCache_2 PF08269.11 AJZ76108.1 - 0.019 14.1 0.0 0.038 13.2 0.0 1.5 1 1 0 1 1 1 0 Cache domain BON PF04972.17 AJZ76108.1 - 0.076 13.3 0.2 0.31 11.4 0.1 2.1 2 0 0 2 2 2 0 BON domain Rad51 PF08423.11 AJZ76109.1 - 6.5e-27 94.4 0.4 7.5e-27 94.2 0.4 1.2 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 AJZ76109.1 - 2.7e-09 36.7 6.5 1.4e-06 27.8 0.1 2.4 2 1 0 2 2 2 2 KaiC DnaB_C PF03796.15 AJZ76109.1 - 1.1e-07 31.4 2.3 0.0012 18.3 0.8 2.1 1 1 0 2 2 2 2 DnaB-like helicase C terminal domain AAA_24 PF13479.6 AJZ76109.1 - 0.00011 22.0 4.6 0.0015 18.3 4.6 2.2 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AJZ76109.1 - 0.00011 22.1 4.0 0.00032 20.7 0.6 2.1 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea RecA PF00154.21 AJZ76109.1 - 0.00012 21.7 0.4 0.00033 20.2 0.4 1.7 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ABC_tran PF00005.27 AJZ76109.1 - 0.00021 21.8 0.2 0.00036 21.0 0.2 1.6 1 1 0 1 1 1 1 ABC transporter Zot PF05707.12 AJZ76109.1 - 0.00091 18.9 0.2 0.0011 18.6 0.2 1.1 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_25 PF13481.6 AJZ76109.1 - 0.0017 18.0 0.0 0.12 12.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 AJZ76109.1 - 0.0071 16.5 1.3 0.01 15.9 1.3 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 AJZ76109.1 - 0.018 14.9 2.3 0.31 11.0 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 AJZ76109.1 - 0.023 15.1 0.0 0.03 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AJZ76109.1 - 0.083 13.2 0.2 0.24 11.7 0.2 1.9 1 1 0 1 1 1 0 AAA domain Cnn_1N PF07989.11 AJZ76109.1 - 0.6 10.3 4.7 4.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Herpes_UL92 PF03048.14 AJZ76109.1 - 0.77 9.5 5.3 1.1 9.1 5.2 1.3 1 1 0 1 1 1 0 UL92 family DEAD PF00270.29 AJZ76110.1 - 8.9e-37 126.5 0.1 2e-36 125.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_assoc PF08494.11 AJZ76110.1 - 2.8e-31 108.8 0.0 6e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/H associated Helicase_C PF00271.31 AJZ76110.1 - 4.5e-21 75.3 0.1 2e-18 66.7 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AJZ76110.1 - 6.5e-13 49.0 0.1 1.8e-11 44.4 0.1 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AJZ76110.1 - 0.0051 17.2 0.0 0.017 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zn-ribbon_8 PF09723.10 AJZ76110.1 - 0.024 14.8 0.5 0.054 13.6 0.5 1.5 1 0 0 1 1 1 0 Zinc ribbon domain SNF2_N PF00176.23 AJZ76110.1 - 0.039 12.7 0.0 0.076 11.7 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF3039 PF11238.8 AJZ76110.1 - 0.046 13.5 1.0 0.13 12.1 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) SpoU_sub_bind PF08032.12 AJZ76110.1 - 0.047 14.0 1.7 5.2 7.4 0.1 3.6 4 0 0 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding AAA_11 PF13086.6 AJZ76110.1 - 0.054 13.3 0.6 0.9 9.3 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.6 AJZ76110.1 - 0.92 9.8 3.2 7.8 6.8 1.2 3.1 2 1 0 2 2 2 0 AAA domain tRNA_anti-codon PF01336.25 AJZ76111.1 - 4.1e-12 45.9 0.1 0.0091 16.0 0.0 3.5 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 AJZ76111.1 - 9e-09 35.4 0.1 0.0036 17.1 0.0 2.3 2 0 0 2 2 2 2 Cell division control protein 24, OB domain 3 REPA_OB_2 PF16900.5 AJZ76111.1 - 3.9e-06 26.7 1.3 0.029 14.3 0.1 3.5 3 0 0 3 3 3 2 Replication protein A OB domain POT1PC PF16686.5 AJZ76111.1 - 0.00053 19.9 0.0 0.48 10.3 0.0 2.8 3 0 0 3 3 3 2 ssDNA-binding domain of telomere protection protein ABC_tran PF00005.27 AJZ76112.1 - 8.1e-29 100.9 0.0 1.4e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AJZ76112.1 - 5.1e-14 52.8 0.0 2.3e-06 27.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 AJZ76112.1 - 3.1e-06 27.8 1.5 4.3e-06 27.4 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 AJZ76112.1 - 0.00018 21.4 0.4 0.46 10.1 0.1 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 AJZ76112.1 - 0.0037 17.0 0.2 0.008 15.9 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AJZ76112.1 - 0.0065 17.0 4.2 0.022 15.3 4.2 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AJZ76112.1 - 0.017 14.5 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 AJZ76112.1 - 0.029 13.8 0.1 4.5 6.6 0.0 2.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Securin PF04856.13 AJZ76112.1 - 0.046 13.7 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor FlgI PF02119.16 AJZ76112.1 - 0.067 12.1 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Flagellar P-ring protein SSL_OB PF09199.10 AJZ76112.1 - 0.081 13.3 0.1 0.25 11.7 0.1 1.8 2 0 0 2 2 2 0 Staphylococcal superantigen-like OB-fold domain MMR_HSR1 PF01926.23 AJZ76112.1 - 3.7 7.6 5.1 11 6.2 1.7 2.9 2 2 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane PF01061.24 AJZ76113.1 - 2.4e-20 72.9 24.2 2.4e-20 72.9 24.2 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AJZ76113.1 - 5.7e-14 52.0 39.2 2e-13 50.2 30.3 2.0 1 1 1 2 2 2 2 ABC-2 family transporter protein DUF354 PF04007.12 AJZ76114.1 - 1.8e-42 145.6 2.9 2.2e-42 145.3 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF354) Epimerase_2 PF02350.19 AJZ76114.1 - 0.0005 19.0 0.2 0.00099 18.1 0.2 1.4 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase LpxB PF02684.15 AJZ76114.1 - 0.0033 16.3 0.2 0.0066 15.3 0.2 1.6 1 1 0 1 1 1 1 Lipid-A-disaccharide synthetase DUF3152 PF11350.8 AJZ76114.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) GrpE PF01025.19 AJZ76116.1 - 6e-34 117.1 0.2 6.6e-34 117.0 0.2 1.0 1 0 0 1 1 1 1 GrpE FANCI_HD2 PF14680.6 AJZ76116.1 - 0.06 12.6 1.1 0.074 12.3 1.1 1.1 1 0 0 1 1 1 0 FANCI helical domain 2 HSP70 PF00012.20 AJZ76117.1 - 2.8e-215 716.0 13.0 7.7e-196 651.9 9.3 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 AJZ76117.1 - 2.7e-16 59.3 4.5 2.7e-16 59.3 4.5 2.4 2 1 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 AJZ76117.1 - 0.00068 19.0 0.7 0.24 10.6 0.0 2.3 1 1 1 2 2 2 2 StbA protein FGGY_C PF02782.16 AJZ76117.1 - 0.0066 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 AJZ76117.1 - 2.5 8.5 7.5 10 6.6 0.2 3.7 4 1 0 4 4 4 0 Cell division protein FtsA eIF-4B PF06273.11 AJZ76117.1 - 3.3 6.7 6.0 5 6.1 6.0 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DnaJ_C PF01556.18 AJZ76118.1 - 5.7e-37 127.1 0.0 7.5e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AJZ76118.1 - 4e-25 87.7 2.7 6.1e-25 87.1 2.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AJZ76118.1 - 5.2e-14 52.4 17.5 9.4e-14 51.5 17.5 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AJZ76118.1 - 0.092 12.7 22.5 1 9.4 8.4 3.1 1 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein GatB_N PF02934.15 AJZ76121.1 - 7.2e-63 212.5 0.0 9.4e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 AJZ76121.1 - 4.6e-17 62.3 0.4 4.6e-17 62.3 0.4 1.7 2 0 0 2 2 2 1 GatB domain GAD PF02938.14 AJZ76121.1 - 1.9e-08 34.4 0.0 5.3e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 GAD domain DUF2092 PF09865.9 AJZ76121.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) Asparaginase PF00710.20 AJZ76122.1 - 1.7e-56 190.8 0.1 2.8e-56 190.1 0.1 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 AJZ76122.1 - 8.4e-27 93.7 0.0 2.1e-26 92.4 0.0 1.6 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain GatD_N PF18195.1 AJZ76122.1 - 3.6e-14 51.8 0.2 1.4e-13 49.9 0.1 2.1 3 0 0 3 3 3 1 GatD N-terminal domain Sec61_beta PF03911.16 AJZ76122.1 - 0.013 15.6 0.4 0.03 14.4 0.4 1.6 1 0 0 1 1 1 0 Sec61beta family AAA PF00004.29 AJZ76123.1 - 8.7e-100 330.3 0.0 5e-50 169.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 AJZ76123.1 - 4.3e-31 106.9 0.8 1.9e-30 104.9 0.2 2.5 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_lid_3 PF17862.1 AJZ76123.1 - 4.1e-24 84.1 0.3 2.8e-13 49.4 0.0 2.8 2 1 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 AJZ76123.1 - 7.1e-16 58.8 0.0 3.7e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 AJZ76123.1 - 7.4e-16 58.3 0.3 6.7e-09 35.7 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AJZ76123.1 - 7.6e-16 59.0 0.1 8e-06 26.3 0.0 3.6 2 1 0 3 3 3 2 AAA ATPase domain TIP49 PF06068.13 AJZ76123.1 - 1.1e-10 41.3 0.0 0.00014 21.2 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 AJZ76123.1 - 2.4e-10 40.8 0.4 0.0026 18.1 0.0 4.0 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.14 AJZ76123.1 - 3.4e-10 40.1 1.3 0.00027 21.0 0.2 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AJZ76123.1 - 1.1e-09 38.4 0.0 0.0013 18.8 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.6 AJZ76123.1 - 1.8e-09 37.9 0.0 0.0024 18.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 AJZ76123.1 - 1.4e-08 34.4 0.1 3.4e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 AJZ76123.1 - 1.1e-07 31.8 0.0 0.0092 15.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 AJZ76123.1 - 2.8e-07 30.4 0.1 0.047 13.4 0.0 3.4 3 1 0 3 3 3 2 Sigma-54 interaction domain RNA_helicase PF00910.22 AJZ76123.1 - 1.1e-06 29.0 0.0 0.044 14.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Bac_DnaA PF00308.18 AJZ76123.1 - 1.2e-06 28.5 0.0 0.0044 16.9 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_18 PF13238.6 AJZ76123.1 - 1.8e-06 28.6 0.1 0.039 14.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain TsaE PF02367.17 AJZ76123.1 - 2.8e-06 27.3 0.0 0.07 13.1 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 AJZ76123.1 - 5.1e-06 25.9 0.0 0.37 9.9 0.0 3.3 3 0 0 3 3 3 2 NB-ARC domain AAA_7 PF12775.7 AJZ76123.1 - 1e-05 25.2 0.0 0.033 13.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 AJZ76123.1 - 1e-05 25.4 0.0 0.035 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 AJZ76123.1 - 1.7e-05 24.3 0.7 0.04 13.3 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AJZ76123.1 - 2.3e-05 24.4 0.3 0.35 10.8 0.1 3.5 3 1 1 4 4 3 2 NACHT domain AAA_28 PF13521.6 AJZ76123.1 - 2.3e-05 24.7 0.0 0.026 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 AJZ76123.1 - 3.3e-05 23.9 0.0 0.029 14.3 0.0 3.3 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 AJZ76123.1 - 0.0001 22.8 0.0 0.82 10.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.12 AJZ76123.1 - 0.00013 21.3 0.5 0.12 11.7 0.0 2.8 3 0 0 3 3 2 1 Zeta toxin DUF815 PF05673.13 AJZ76123.1 - 0.0002 20.6 0.0 0.078 12.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 AJZ76123.1 - 0.00032 20.5 0.0 0.46 10.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 AJZ76123.1 - 0.00044 19.7 4.7 0.34 10.2 0.0 4.3 4 1 1 5 5 4 1 KaiC PhoH PF02562.16 AJZ76123.1 - 0.0005 19.6 0.1 0.42 10.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.6 AJZ76123.1 - 0.0031 17.1 10.4 1.4 8.5 0.2 4.8 2 2 1 3 3 3 1 AAA domain Cytidylate_kin PF02224.18 AJZ76123.1 - 0.0041 16.9 0.1 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase TniB PF05621.11 AJZ76123.1 - 0.0051 16.3 0.0 2.2 7.6 0.0 3.0 3 0 0 3 3 2 1 Bacterial TniB protein AAA_30 PF13604.6 AJZ76123.1 - 0.0064 16.2 0.2 1.8 8.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 AJZ76123.1 - 0.0066 16.4 1.9 4.8 7.1 0.0 3.8 3 1 1 4 4 3 0 NTPase AAA_17 PF13207.6 AJZ76123.1 - 0.007 16.8 0.0 1.2 9.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.16 AJZ76123.1 - 0.01 14.8 0.1 3.2 6.5 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase DUF2075 PF09848.9 AJZ76123.1 - 0.012 14.9 0.0 0.39 9.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Guanylate_kin PF00625.21 AJZ76123.1 - 0.014 15.1 0.7 8 6.1 0.0 3.7 3 1 1 4 4 3 0 Guanylate kinase Parvo_NS1 PF01057.17 AJZ76123.1 - 0.014 14.5 0.0 0.3 10.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 AJZ76123.1 - 0.019 14.7 0.0 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 AJZ76123.1 - 0.021 15.0 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP-synt_ab PF00006.25 AJZ76123.1 - 0.036 13.7 0.0 5.8 6.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 AJZ76123.1 - 0.036 14.0 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase CPT PF07931.12 AJZ76123.1 - 0.041 13.7 0.1 6.4 6.6 0.0 2.9 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.15 AJZ76123.1 - 0.043 13.7 0.0 15 5.5 0.0 3.1 2 1 1 3 3 3 0 Rad17 P-loop domain AAA_11 PF13086.6 AJZ76123.1 - 0.053 13.3 0.0 0.64 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 AJZ76123.1 - 0.059 13.6 0.2 23 5.2 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 AJZ76123.1 - 0.073 12.8 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 AJZ76123.1 - 0.074 12.8 0.0 22 4.8 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 AJZ76123.1 - 0.096 12.7 0.0 19 5.2 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Vps4_C PF09336.10 AJZ76123.1 - 0.16 12.0 0.5 31 4.7 0.0 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_19 PF13245.6 AJZ76123.1 - 0.62 10.4 4.3 4.5 7.6 0.1 3.5 3 2 0 4 4 3 0 AAA domain Ribosomal_L2_C PF03947.18 AJZ76124.1 - 3.9e-35 120.8 3.2 3.9e-34 117.6 3.3 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AJZ76124.1 - 2.2e-07 30.7 0.0 6.4e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain NIL PF09383.10 AJZ76124.1 - 0.02 14.7 0.1 0.037 13.9 0.1 1.5 1 0 0 1 1 1 0 NIL domain Acylphosphatase PF00708.18 AJZ76125.1 - 2.5e-23 82.3 0.9 2.8e-23 82.1 0.9 1.0 1 0 0 1 1 1 1 Acylphosphatase ATP_bind_3 PF01171.20 AJZ76127.1 - 3.3e-20 72.6 0.0 4.8e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 PP-loop family CTU2 PF10288.9 AJZ76127.1 - 0.0046 17.2 3.5 0.23 11.7 2.6 2.9 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 tRNA_Me_trans PF03054.16 AJZ76127.1 - 0.0073 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 AJZ76127.1 - 0.0088 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 NAD synthase PAPS_reduct PF01507.19 AJZ76127.1 - 0.04 14.0 0.0 0.08 13.0 0.0 1.8 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family C1_1 PF00130.22 AJZ76127.1 - 6.8 6.7 17.8 0.052 13.4 2.8 3.6 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_M50 PF02163.22 AJZ76128.1 - 1.4e-20 73.6 0.4 2e-18 66.6 0.4 2.2 1 1 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 AJZ76128.1 - 1.2e-08 35.1 0.0 2.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 AJZ76128.1 - 5.2e-06 26.2 0.0 8.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AJZ76128.1 - 0.00016 21.9 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain BphX PF06139.12 AJZ76128.1 - 0.12 12.3 0.3 0.12 12.3 0.3 2.1 2 0 0 2 2 2 0 BphX-like eRF1_1 PF03463.15 AJZ76129.1 - 7.7e-16 58.3 1.9 1.4e-15 57.4 1.9 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 AJZ76129.1 - 3.5e-10 40.4 3.4 6.4e-10 39.5 0.5 2.6 3 0 0 3 3 3 1 eRF1 domain 3 eRF1_2 PF03464.15 AJZ76129.1 - 0.00013 22.3 0.0 0.00046 20.5 0.0 1.9 1 1 0 1 1 1 1 eRF1 domain 2 baeRF_family7 PF18849.1 AJZ76129.1 - 0.043 14.0 0.3 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 UPF0047 PF01894.17 AJZ76131.1 - 3.9e-37 126.9 0.0 4.5e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fe_dep_repr_C PF02742.15 AJZ76132.1 - 9.1e-19 67.3 0.1 1.7e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.19 AJZ76132.1 - 2.5e-16 59.6 0.3 4e-16 58.9 0.3 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 AJZ76132.1 - 4.3e-05 23.3 0.0 6.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AJZ76132.1 - 4.9e-05 23.7 0.0 8.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.20 AJZ76132.1 - 8.7e-05 22.8 0.1 0.00017 21.9 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AJZ76132.1 - 9.7e-05 22.2 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 AJZ76132.1 - 0.00016 21.5 0.0 0.00041 20.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 AJZ76132.1 - 0.0011 18.8 0.1 0.0018 18.1 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AJZ76132.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_1 PF00126.27 AJZ76132.1 - 0.0038 17.1 0.0 0.0088 16.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_45 PF14947.6 AJZ76132.1 - 0.0049 16.8 0.1 0.0071 16.3 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix TFIIE_beta PF02186.15 AJZ76132.1 - 0.0068 16.7 0.2 0.019 15.3 0.1 1.7 2 0 0 2 2 2 1 TFIIE beta subunit core domain HTH_12 PF08461.10 AJZ76132.1 - 0.038 13.9 0.0 0.083 12.9 0.0 1.5 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_11 PF08279.12 AJZ76132.1 - 0.046 13.7 0.1 0.078 12.9 0.1 1.3 1 0 0 1 1 1 0 HTH domain NLPC_P60 PF00877.19 AJZ76132.1 - 0.05 13.6 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 NlpC/P60 family HTH_37 PF13744.6 AJZ76132.1 - 0.051 13.5 0.3 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Talin_middle PF09141.10 AJZ76132.1 - 0.078 13.0 0.1 0.097 12.7 0.1 1.1 1 0 0 1 1 1 0 Talin, middle domain Rio2_N PF09202.11 AJZ76132.1 - 0.098 12.9 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Rio2, N-terminal HTH_6 PF01418.17 AJZ76132.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family IF2_N PF04760.15 AJZ76132.1 - 0.1 12.4 0.3 0.33 10.8 0.1 1.9 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region SMC_ScpB PF04079.16 AJZ76132.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB HTH_IclR PF09339.10 AJZ76132.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain TrmB PF01978.19 AJZ76133.1 - 7.8e-23 80.1 0.5 2.2e-21 75.5 0.0 3.0 3 1 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 AJZ76133.1 - 9.6e-08 31.5 0.0 1.2e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_IclR PF09339.10 AJZ76133.1 - 0.00017 21.3 0.0 0.00049 19.9 0.0 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AJZ76133.1 - 0.0011 18.5 0.0 0.0036 16.8 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 AJZ76133.1 - 0.0064 17.0 0.0 0.034 14.6 0.0 2.2 3 0 0 3 3 3 1 Winged helix DNA-binding domain Penicillinase_R PF03965.16 AJZ76133.1 - 0.016 15.5 0.2 0.24 11.8 0.0 2.2 2 0 0 2 2 2 0 Penicillinase repressor Rrf2 PF02082.20 AJZ76133.1 - 0.039 14.3 0.1 0.4 11.1 0.0 2.3 2 1 0 2 2 2 0 Transcriptional regulator GntR PF00392.21 AJZ76133.1 - 0.094 12.4 0.1 1.4 8.6 0.0 2.6 3 1 0 3 3 3 0 Bacterial regulatory proteins, gntR family PadR PF03551.14 AJZ76133.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family PheRS_DBD3 PF18553.1 AJZ76133.1 - 0.12 12.7 0.1 0.46 10.8 0.1 2.1 1 1 0 1 1 1 0 PheRS DNA binding domain 3 PLDc_2 PF13091.6 AJZ76133.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 PLD-like domain HTH_9 PF08221.11 AJZ76133.1 - 0.16 12.1 1.1 0.33 11.1 0.0 2.1 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Glycos_transf_1 PF00534.20 AJZ76134.1 - 2.9e-23 82.3 0.4 4.3e-22 78.4 0.4 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AJZ76134.1 - 3.3e-16 59.9 0.0 5.8e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AJZ76134.1 - 5.3e-09 36.3 0.1 7.3e-08 32.6 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AJZ76134.1 - 1.3e-07 31.9 0.0 2.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AJZ76134.1 - 8.9e-05 22.5 0.2 0.00035 20.6 0.2 2.1 1 1 1 2 2 2 1 Glycosyl transferase 4-like Epimerase_2 PF02350.19 AJZ76134.1 - 0.0053 15.7 0.5 0.015 14.2 0.1 1.8 2 0 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 AJZ76134.1 - 0.0062 17.0 0.0 0.013 16.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Epimerase PF01370.21 AJZ76135.1 - 5.8e-57 192.9 0.0 6.8e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJZ76135.1 - 3.2e-51 174.7 0.1 3.4e-50 171.3 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AJZ76135.1 - 2.1e-26 92.6 0.0 2.9e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AJZ76135.1 - 2.3e-20 72.9 0.0 2.8e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AJZ76135.1 - 2.8e-19 69.4 0.1 1.6e-18 66.9 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AJZ76135.1 - 7.7e-16 58.0 0.0 1.2e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 AJZ76135.1 - 7.9e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 AJZ76135.1 - 0.00044 20.2 0.1 0.0081 16.1 0.1 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 AJZ76135.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Ldh_1_N PF00056.23 AJZ76135.1 - 0.039 14.0 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Asn_synthase PF00733.21 AJZ76136.1 - 6.2e-35 121.5 0.0 7.9e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 AJZ76136.1 - 0.00026 20.8 0.2 0.0035 17.1 0.1 2.4 2 0 0 2 2 2 1 PP-loop family NAD_synthase PF02540.17 AJZ76136.1 - 0.00033 19.9 0.2 0.0015 17.7 0.0 2.1 3 0 0 3 3 3 1 NAD synthase tRNA_Me_trans PF03054.16 AJZ76136.1 - 0.032 13.0 0.0 0.059 12.2 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase QueC PF06508.13 AJZ76136.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Glycos_transf_1 PF00534.20 AJZ76137.1 - 2.8e-22 79.1 0.0 4.5e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AJZ76137.1 - 5.6e-20 72.1 0.0 8.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AJZ76137.1 - 5.1e-09 36.4 0.0 1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AJZ76137.1 - 0.00019 21.5 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Strep_his_triad PF04270.13 AJZ76137.1 - 0.068 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Streptococcal histidine triad protein Phage_integr_3 PF16795.5 AJZ76137.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal phage integrase Methyltransf_11 PF08241.12 AJZ76138.1 - 1.4e-15 57.7 0.0 2.8e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJZ76138.1 - 1.9e-14 53.7 0.1 3e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJZ76138.1 - 6.3e-14 52.1 0.0 4.2e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJZ76138.1 - 1.2e-13 51.6 0.0 2.7e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJZ76138.1 - 4.8e-08 33.6 0.0 8.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AJZ76138.1 - 4.3e-07 29.5 0.2 4e-06 26.3 0.1 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 AJZ76138.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Elf1 PF05129.13 AJZ76138.1 - 0.074 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Glycos_transf_1 PF00534.20 AJZ76139.1 - 4.8e-23 81.5 0.0 2.1e-22 79.5 0.0 2.0 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AJZ76139.1 - 2.3e-19 70.2 0.0 4.9e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AJZ76139.1 - 1.2e-08 35.2 0.0 2.7e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AJZ76139.1 - 1.6e-05 24.9 0.0 3.8e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 TylF PF05711.11 AJZ76140.1 - 1e-07 31.5 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 AJZ76140.1 - 2e-07 32.0 0.0 3.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 AJZ76141.1 - 2e-49 168.2 0.0 2.6e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJZ76141.1 - 2.6e-44 152.0 0.0 3.2e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AJZ76141.1 - 2.8e-19 69.2 0.0 4e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AJZ76141.1 - 6.2e-17 61.7 0.1 4.6e-16 58.8 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AJZ76141.1 - 1.6e-14 53.7 0.0 2.1e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AJZ76141.1 - 5.8e-12 45.3 0.1 9.7e-08 31.5 0.0 2.7 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 AJZ76141.1 - 6.4e-09 36.0 0.0 1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 AJZ76141.1 - 2.3e-07 30.5 0.1 1.2e-05 24.9 0.1 2.5 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 AJZ76141.1 - 3.5e-05 23.5 0.0 6.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 AJZ76141.1 - 0.0043 17.1 0.0 0.011 15.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 AJZ76141.1 - 0.0065 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AJZ76141.1 - 0.012 15.6 0.0 0.033 14.1 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 AJZ76141.1 - 0.014 14.9 0.0 0.24 10.9 0.0 2.2 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJZ76141.1 - 0.02 14.8 1.1 0.074 13.0 0.4 2.3 2 1 0 2 2 2 0 KR domain Sacchrp_dh_NADP PF03435.18 AJZ76141.1 - 0.021 15.1 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glycos_transf_1 PF00534.20 AJZ76142.1 - 1.4e-33 115.8 0.0 2.2e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AJZ76142.1 - 3.9e-22 79.1 0.0 5.9e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AJZ76142.1 - 8.3e-13 48.7 0.1 1.7e-11 44.4 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AJZ76142.1 - 2.4e-05 24.6 0.0 5.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 zf_C2H2_13 PF18508.1 AJZ76142.1 - 0.048 13.3 0.6 0.63 9.7 0.1 2.7 3 0 0 3 3 3 0 Zinc finger domain Glyco_trans_4_4 PF13579.6 AJZ76142.1 - 0.27 11.7 0.0 5.9 7.3 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain GDP_Man_Dehyd PF16363.5 AJZ76143.1 - 1.4e-53 182.5 0.1 1.7e-53 182.2 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AJZ76143.1 - 4.7e-49 167.0 0.0 5.7e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AJZ76143.1 - 3.8e-17 62.3 0.0 4.4e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AJZ76143.1 - 3.5e-12 45.9 0.1 4.5e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AJZ76143.1 - 2e-08 33.7 0.1 4.4e-08 32.6 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AJZ76143.1 - 4.9e-08 32.4 0.0 0.00063 19.0 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 AJZ76143.1 - 6.2e-07 29.7 0.0 1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 AJZ76143.1 - 5.6e-05 23.1 0.0 7.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AJZ76143.1 - 8.6e-05 22.5 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 AJZ76143.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 AJZ76143.1 - 0.0061 16.0 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_transf_4 PF13439.6 AJZ76143.1 - 0.0077 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 NmrA PF05368.13 AJZ76143.1 - 0.0084 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Glyco_transf_5 PF08323.11 AJZ76143.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF3473 PF11959.8 AJZ76144.1 - 4e-31 107.7 0.2 6e-31 107.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3473) Polysacc_deac_1 PF01522.21 AJZ76144.1 - 3.4e-13 49.6 0.0 6.5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase YWFCY PF14293.6 AJZ76144.1 - 0.09 13.1 0.7 4 7.8 0.1 3.3 4 1 0 4 4 4 0 YWFCY protein Hexapep PF00132.24 AJZ76145.1 - 3e-11 42.6 10.8 3.5e-06 26.5 1.8 3.7 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AJZ76145.1 - 6.2e-08 32.3 8.3 0.0035 17.1 2.7 3.9 3 1 2 5 5 5 3 Hexapeptide repeat of succinyl-transferase Acid_PPase PF12689.7 AJZ76146.1 - 1.4e-05 25.0 0.4 0.011 15.6 0.1 2.6 2 0 0 2 2 2 2 Acid Phosphatase NIF PF03031.18 AJZ76146.1 - 0.00025 20.9 0.0 0.00061 19.6 0.0 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Acetyltransf_4 PF13420.7 AJZ76146.1 - 0.049 13.8 0.1 0.049 13.8 0.1 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain PP-binding PF00550.25 AJZ76147.1 - 0.006 16.9 0.0 0.021 15.2 0.0 1.7 1 1 0 1 1 1 1 Phosphopantetheine attachment site DUF3013 PF11217.8 AJZ76147.1 - 0.049 13.5 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3013) MaoC_dehydratas PF01575.19 AJZ76148.1 - 4.2e-21 74.8 0.0 5.2e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AJZ76148.1 - 4.3e-09 36.6 0.0 1.5e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 AJZ76148.1 - 0.16 12.3 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily ACPS PF01648.20 AJZ76149.1 - 9.3e-14 51.5 0.2 1.1e-13 51.3 0.2 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 AJZ76149.1 - 0.016 15.3 0.1 0.068 13.3 0.1 1.9 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain NTP_transferase PF00483.23 AJZ76150.1 - 9.6e-57 192.4 0.0 1.2e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 AJZ76150.1 - 1.8e-11 43.3 11.1 2.4e-07 30.2 2.2 4.0 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 AJZ76150.1 - 3.9e-11 43.6 0.0 5.4e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 AJZ76150.1 - 1.8e-06 27.6 7.2 3.4e-06 26.7 2.8 3.0 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 AJZ76150.1 - 0.03 13.3 0.2 0.046 12.7 0.2 1.3 1 0 0 1 1 1 0 L-fucokinase DUF4954 PF16314.5 AJZ76150.1 - 0.1 10.7 8.4 0.16 10.1 3.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 AJZ76150.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase Ribonuclease_3 PF00636.26 AJZ76150.1 - 0.17 12.6 0.0 0.31 11.7 0.0 1.5 1 1 0 1 1 1 0 Ribonuclease III domain GDP_Man_Dehyd PF16363.5 AJZ76151.1 - 6.4e-75 252.6 0.0 7.3e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AJZ76151.1 - 6.9e-58 196.0 0.0 9.1e-58 195.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AJZ76151.1 - 2.2e-20 72.8 0.0 3e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AJZ76151.1 - 2.8e-16 59.4 0.0 3.1e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AJZ76151.1 - 1e-13 51.1 0.0 2.8e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AJZ76151.1 - 5.3e-10 38.9 1.1 1.2e-08 34.4 1.1 2.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 AJZ76151.1 - 1.3e-05 25.2 0.0 3.8e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 AJZ76151.1 - 0.0024 17.3 0.0 0.0069 15.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KIAA1430 PF13879.6 AJZ76151.1 - 0.16 12.8 3.7 0.56 11.0 0.9 2.5 2 0 0 2 2 2 0 KIAA1430 homologue FdtA PF05523.11 AJZ76152.1 - 4.2e-18 65.3 0.1 5e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 WxcM-like, C-terminal Cupin_2 PF07883.11 AJZ76152.1 - 0.00017 21.2 0.0 0.00052 19.7 0.0 1.9 1 1 0 1 1 1 1 Cupin domain Glycos_transf_2 PF00535.26 AJZ76153.1 - 6e-23 81.5 0.1 8e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AJZ76153.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PrpR_N PF06506.11 AJZ76153.1 - 0.042 13.4 0.1 0.67 9.5 0.1 2.3 2 0 0 2 2 2 0 Propionate catabolism activator RseC_MucC PF04246.12 AJZ76153.1 - 0.094 12.7 0.4 0.15 12.0 0.4 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Glyco_tranf_2_4 PF13704.6 AJZ76153.1 - 0.16 12.5 0.0 0.36 11.4 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Promethin PF16015.5 AJZ76153.1 - 0.54 10.2 5.0 0.83 9.6 5.0 1.3 1 0 0 1 1 1 0 Promethin RmlD_sub_bind PF04321.17 AJZ76154.1 - 2.7e-52 177.7 0.0 3.3e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AJZ76154.1 - 1.6e-19 70.3 0.0 2.1e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJZ76154.1 - 4.4e-11 42.8 0.6 2.6e-10 40.2 0.6 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AJZ76154.1 - 2.4e-08 33.5 3.6 5.2e-06 25.8 0.4 2.5 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AJZ76154.1 - 7.3e-08 31.7 2.5 1.8e-07 30.4 2.5 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AJZ76154.1 - 5e-07 29.1 0.9 8.7e-06 25.1 0.1 2.8 3 1 0 3 3 3 1 Male sterility protein NAD_binding_10 PF13460.6 AJZ76154.1 - 0.00079 19.4 0.0 0.0041 17.0 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 AJZ76154.1 - 0.027 14.9 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 AJZ76154.1 - 0.078 12.5 0.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 NmrA-like family dTDP_sugar_isom PF00908.17 AJZ76155.1 - 4.8e-62 208.6 0.0 5.2e-62 208.5 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase ARD PF03079.14 AJZ76155.1 - 0.0078 16.4 0.4 0.0095 16.1 0.4 1.2 1 0 0 1 1 1 1 ARD/ARD' family FdtA PF05523.11 AJZ76155.1 - 0.012 15.3 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal Methyltransf_14 PF08484.11 AJZ76156.1 - 1.7e-63 213.2 0.0 3.4e-63 212.2 0.0 1.5 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Methyltransf_13 PF08421.11 AJZ76156.1 - 3.7e-18 65.5 0.7 6.1e-18 64.8 0.7 1.4 1 0 0 1 1 1 1 Putative zinc binding domain Methyltransf_23 PF13489.6 AJZ76156.1 - 1.6e-17 63.9 0.1 3.9e-17 62.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJZ76156.1 - 4e-09 37.0 0.0 2e-08 34.8 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJZ76156.1 - 5.5e-08 33.5 0.0 1.4e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJZ76156.1 - 5.7e-07 29.4 0.0 2.3e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJZ76156.1 - 5e-06 27.1 0.0 1.4e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AJZ76156.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF1819 PF08849.11 AJZ76156.1 - 0.055 13.3 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) NTP_transferase PF00483.23 AJZ76157.1 - 2.7e-18 66.4 0.0 6.1e-18 65.3 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AJZ76157.1 - 2.9e-07 31.0 0.0 4.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AJZ76157.1 - 0.18 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glyco_trans_1_2 PF13524.6 AJZ76158.1 - 2.8e-07 30.8 0.0 1.7e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Capsule_synth PF05159.14 AJZ76159.1 - 4.2e-05 23.1 0.2 6.9e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein DUF354 PF04007.12 AJZ76159.1 - 0.00022 20.4 0.0 0.00046 19.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF354) Epimerase_2 PF02350.19 AJZ76159.1 - 0.00048 19.1 0.0 0.00091 18.2 0.0 1.4 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Polysacc_synt PF01943.17 AJZ76160.1 - 1.6e-05 24.4 52.1 5.5e-05 22.7 30.4 3.0 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 AJZ76160.1 - 0.004 17.2 10.1 0.004 17.2 10.1 3.8 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain AhpC-TSA PF00578.21 AJZ76161.1 - 0.098 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family Epimerase_2 PF02350.19 AJZ76162.1 - 1.1e-79 267.9 0.3 1.2e-79 267.7 0.3 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Peroxin-22 PF12827.7 AJZ76162.1 - 0.027 14.4 0.6 0.31 11.0 0.6 2.8 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family DRTGG PF07085.12 AJZ76162.1 - 0.063 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 DRTGG domain ptaRNA1_toxin PF12703.7 AJZ76162.1 - 0.18 11.8 0.0 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system NeuB PF03102.14 AJZ76163.1 - 1.7e-69 234.0 0.0 2e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 AJZ76163.1 - 3.8e-09 37.0 0.0 1.2e-08 35.5 0.0 1.9 2 0 0 2 2 2 1 SAF domain CTP_transf_3 PF02348.19 AJZ76164.1 - 2.8e-21 76.5 0.0 3.4e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AJZ76164.1 - 0.00014 22.3 0.0 0.00018 21.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AJZ76164.1 - 0.13 12.0 0.1 0.17 11.6 0.1 1.3 1 1 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GFO_IDH_MocA PF01408.22 AJZ76165.1 - 6.1e-19 69.0 0.0 1.1e-18 68.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AJZ76165.1 - 4.3e-05 23.5 0.0 7.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ApbA PF02558.16 AJZ76165.1 - 0.003 17.2 0.0 0.0062 16.2 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 AJZ76165.1 - 0.003 17.7 0.1 0.18 11.9 0.0 2.6 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 AJZ76165.1 - 0.0033 17.7 0.1 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 AJZ76165.1 - 0.0039 16.6 0.0 0.047 13.0 0.0 2.3 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 AJZ76165.1 - 0.0054 17.0 0.3 0.06 13.7 0.0 2.7 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain IlvN PF07991.12 AJZ76165.1 - 0.0069 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 AJZ76165.1 - 0.011 16.0 0.0 0.03 14.6 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 AJZ76165.1 - 0.027 14.9 0.3 0.085 13.3 0.0 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding Glyphos_transf PF04464.14 AJZ76166.1 - 0.0019 17.2 0.0 0.006 15.6 0.0 1.7 1 1 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Abhydro_lipase PF04083.16 AJZ76166.1 - 0.023 14.3 0.0 0.08 12.5 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Trans_coact PF16805.5 AJZ76166.1 - 0.034 14.3 1.0 0.14 12.3 1.0 2.1 1 0 0 1 1 1 0 Phage late-transcription coactivator Polyketide_cyc PF03364.20 AJZ76167.1 - 0.01 16.1 0.0 0.015 15.5 0.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AJZ76167.1 - 0.043 14.1 0.0 0.053 13.8 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DUF896 PF05979.12 AJZ76167.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) 2OG-FeII_Oxy_4 PF13661.6 AJZ76168.1 - 0.0027 18.3 0.0 0.033 14.8 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 AJZ76168.1 - 0.0046 17.8 0.0 0.0071 17.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Polysacc_synt_2 PF02719.15 AJZ76169.1 - 1.4e-97 326.4 1.4 1.9e-97 325.9 1.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AJZ76169.1 - 3.3e-26 92.2 0.7 2.9e-25 89.1 0.7 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AJZ76169.1 - 1.1e-21 77.1 1.2 3.3e-19 69.0 0.1 2.3 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AJZ76169.1 - 7.1e-17 61.8 0.2 6.2e-15 55.4 0.2 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AJZ76169.1 - 1.4e-13 50.6 0.0 6.4e-12 45.2 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AJZ76169.1 - 9.1e-12 45.2 0.0 1.9e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AJZ76169.1 - 8.2e-10 38.3 3.5 9.9e-07 28.2 1.5 3.1 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 AJZ76169.1 - 1e-06 28.4 0.2 4.6e-06 26.2 0.1 2.2 2 1 0 2 2 2 1 short chain dehydrogenase Shikimate_DH PF01488.20 AJZ76169.1 - 2.1e-06 27.8 0.2 2.1e-06 27.8 0.2 2.7 3 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase KR PF08659.10 AJZ76169.1 - 2.3e-06 27.6 0.0 4.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 AJZ76169.1 - 7.6e-06 25.6 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 AJZ76169.1 - 0.00031 21.3 0.0 0.0012 19.3 0.0 2.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AJZ76169.1 - 0.00038 20.7 0.5 0.0052 17.1 0.0 2.5 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 AJZ76169.1 - 0.003 18.0 0.0 0.034 14.6 0.0 2.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_syn_2C PF08485.10 AJZ76169.1 - 0.014 15.1 0.2 0.031 14.0 0.2 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal NAD_Gly3P_dh_N PF01210.23 AJZ76169.1 - 0.016 15.2 0.1 0.049 13.6 0.0 1.9 2 1 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus S_100 PF01023.19 AJZ76169.1 - 0.05 13.3 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain PLDc_2 PF13091.6 AJZ76169.1 - 0.085 12.7 1.7 1.6 8.6 0.1 2.5 2 2 0 2 2 2 0 PLD-like domain CTP_transf_3 PF02348.19 AJZ76170.1 - 3.7e-33 115.3 0.3 4.3e-33 115.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AJZ76170.1 - 0.01 16.2 0.0 0.097 13.0 0.0 2.1 1 1 0 1 1 1 0 MobA-like NTP transferase domain Baculo_LEF-11 PF06385.12 AJZ76170.1 - 0.4 11.2 6.5 0.13 12.8 1.0 2.2 2 0 0 2 2 2 0 Baculovirus LEF-11 protein NeuB PF03102.14 AJZ76171.1 - 1.2e-76 257.4 0.0 1.5e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 AJZ76171.1 - 0.0089 16.6 0.2 0.03 14.9 0.0 2.0 3 0 0 3 3 3 1 SAF domain Formyl_trans_N PF00551.19 AJZ76172.1 - 5.3e-14 52.4 0.0 7.4e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 AJZ76172.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain Acetyltransf_4 PF13420.7 AJZ76173.1 - 1.8e-16 60.6 2.9 2.1e-16 60.4 2.9 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AJZ76173.1 - 2.1e-11 44.6 0.5 2.7e-11 44.3 0.5 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AJZ76173.1 - 0.014 15.6 0.0 0.018 15.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AJZ76173.1 - 0.044 13.5 0.0 0.95 9.1 0.1 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TrkA_N PF02254.18 AJZ76174.1 - 0.032 14.5 0.0 0.3 11.4 0.0 2.4 3 0 0 3 3 3 0 TrkA-N domain bact-PGI_C PF10432.9 AJZ76175.1 - 1.2e-36 126.0 0.0 2.3e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal SIS domain SIS PF01380.22 AJZ76175.1 - 6e-07 29.4 0.9 1.4e-06 28.2 0.2 1.9 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 AJZ76175.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.1 3 0 0 3 3 3 0 SIS domain IF-2B PF01008.17 AJZ76176.1 - 3.3e-86 289.0 1.0 3.9e-86 288.8 1.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family FeS_assembly_P PF01883.19 AJZ76177.1 - 4.8e-18 65.1 0.1 1.8e-17 63.3 0.1 1.9 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein PqqD PF05402.12 AJZ76177.1 - 6.2e-10 39.2 0.0 1.2e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) HMA PF00403.26 AJZ76177.1 - 0.16 12.4 0.1 0.35 11.3 0.1 1.5 1 0 0 1 1 1 0 Heavy-metal-associated domain tRNA-synt_2c PF01411.19 AJZ76178.1 - 0.083 11.4 0.0 0.098 11.2 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (A) Aminotran_1_2 PF00155.21 AJZ76179.1 - 7.6e-59 199.7 0.0 8.6e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AJZ76179.1 - 3.8e-09 36.3 0.0 5.6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AJZ76179.1 - 3.2e-06 26.4 0.0 7.8e-06 25.1 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AJZ76179.1 - 0.0003 19.4 0.0 0.00044 18.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 AJZ76179.1 - 0.0022 16.9 0.0 0.0048 15.7 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 AJZ76179.1 - 0.0042 16.4 0.0 0.0065 15.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Putative_PNPOx PF01243.20 AJZ76180.1 - 2.9e-16 59.4 0.0 4.1e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 AJZ76180.1 - 5.7e-08 32.9 0.0 1.2e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 AJZ76180.1 - 0.0048 16.5 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like DUF2373 PF10180.9 AJZ76180.1 - 0.0083 15.9 0.1 0.019 14.8 0.1 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) L6_membrane PF05805.12 AJZ76181.1 - 0.0023 17.6 1.3 0.0028 17.3 1.3 1.0 1 0 0 1 1 1 1 L6 membrane protein DUF308 PF03729.13 AJZ76181.1 - 0.0029 17.9 0.6 0.037 14.3 0.0 2.1 2 0 0 2 2 2 1 Short repeat of unknown function (DUF308) YfzA PF14118.6 AJZ76181.1 - 0.0042 17.4 0.2 0.0048 17.3 0.2 1.1 1 0 0 1 1 1 1 YfzA-like protein CrgA PF06781.12 AJZ76181.1 - 0.096 12.8 1.3 0.11 12.6 1.3 1.1 1 0 0 1 1 1 0 Cell division protein CrgA F420_oxidored PF03807.17 AJZ76182.1 - 8.2e-15 55.2 0.0 1.6e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AJZ76182.1 - 0.021 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AJZ76182.1 - 0.025 14.6 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Semialdhyde_dh PF01118.24 AJZ76182.1 - 0.033 14.6 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 AJZ76182.1 - 0.12 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus His_Phos_1 PF00300.22 AJZ76183.1 - 1.9e-49 168.0 0.0 2.1e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M42 PF05343.14 AJZ76183.1 - 0.037 13.1 0.2 0.49 9.4 0.2 2.0 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase COX2_TM PF02790.15 AJZ76184.1 - 0.021 15.0 1.5 0.032 14.4 0.0 1.8 1 1 1 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF4059 PF13268.6 AJZ76184.1 - 0.022 15.2 1.1 0.082 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) DUF2391 PF09622.10 AJZ76184.1 - 0.027 13.8 0.2 0.03 13.7 0.2 1.0 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) COX2 PF00116.20 AJZ76185.1 - 2.7e-16 59.6 0.6 8.1e-12 45.1 0.0 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.6 AJZ76185.1 - 6.4e-06 26.2 0.0 7.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain DUF4261 PF14080.6 AJZ76185.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) COX1 PF00115.20 AJZ76186.1 - 5.1e-128 427.6 61.3 5.1e-128 427.6 61.3 1.6 1 1 1 2 2 2 2 Cytochrome C and Quinol oxidase polypeptide I Kinocilin PF15033.6 AJZ76186.1 - 2.3 7.9 3.9 14 5.4 0.0 3.2 3 0 0 3 3 3 0 Kinocilin protein Copper-bind PF00127.20 AJZ76187.1 - 3.5e-16 59.5 0.7 4.3e-08 33.5 0.1 2.5 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu-oxidase_3 PF07732.15 AJZ76187.1 - 1.5e-12 47.5 0.1 3.8e-05 23.7 0.0 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 AJZ76187.1 - 2.4e-08 34.0 0.0 0.00047 20.2 0.0 2.7 2 1 0 2 2 2 2 Cupredoxin-like domain SoxE PF06525.11 AJZ76187.1 - 3.9e-07 29.7 4.1 0.00067 19.2 0.1 3.2 2 2 0 2 2 2 2 Sulfocyanin (SoxE) domain Cu-oxidase_2 PF07731.14 AJZ76187.1 - 1.7e-05 24.6 0.0 0.2 11.4 0.0 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu_bind_like PF02298.17 AJZ76187.1 - 0.0048 16.9 0.0 0.39 10.8 0.0 2.7 2 1 0 2 2 2 1 Plastocyanin-like domain DUF2475 PF10629.9 AJZ76187.1 - 0.037 14.2 0.0 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2475) Glyco_transf_6 PF03414.13 AJZ76187.1 - 0.19 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 COX15-CtaA PF02628.15 AJZ76188.1 - 3.1e-18 65.9 16.9 3.4e-12 46.1 10.5 2.0 1 1 1 2 2 2 2 Cytochrome oxidase assembly protein Endonuc_Holl PF10107.9 AJZ76189.1 - 6.2e-05 22.9 0.4 0.00049 20.0 0.1 2.1 2 0 0 2 2 2 1 Endonuclease related to archaeal Holliday junction resolvase DUF4263 PF14082.6 AJZ76189.1 - 0.049 13.9 0.0 8.4 6.6 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4263) Alpha-2-MRAP_N PF06400.11 AJZ76189.1 - 0.072 13.1 0.6 0.36 10.8 0.2 1.9 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain DUF2897 PF11446.8 AJZ76189.1 - 0.073 13.0 0.3 0.14 12.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Wzz PF02706.15 AJZ76189.1 - 0.082 13.2 0.3 0.13 12.6 0.3 1.3 1 0 0 1 1 1 0 Chain length determinant protein Lar_restr_allev PF14354.6 AJZ76190.1 - 0.0034 17.7 0.2 2.1 8.8 0.1 2.3 2 0 0 2 2 2 2 Restriction alleviation protein Lar zf-H2C2_2 PF13465.6 AJZ76190.1 - 0.0038 17.6 3.0 0.25 11.9 0.6 2.2 2 0 0 2 2 2 1 Zinc-finger double domain DUF1178 PF06676.11 AJZ76190.1 - 0.006 17.0 1.3 0.11 12.9 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1178) zf-ribbon_3 PF13248.6 AJZ76190.1 - 0.019 14.4 3.0 1.3 8.5 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AJZ76190.1 - 0.021 14.9 0.4 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 AJZ76190.1 - 0.024 14.9 0.3 3.8 7.8 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon PADR1 PF08063.12 AJZ76190.1 - 0.032 14.0 1.1 4.2 7.2 0.1 2.2 2 0 0 2 2 2 0 PADR1 (NUC008) domain Zn_Tnp_IS1595 PF12760.7 AJZ76190.1 - 0.045 13.7 0.2 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-Di19 PF05605.12 AJZ76190.1 - 0.045 14.0 0.3 1.9 8.8 0.1 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_7 PF02591.15 AJZ76190.1 - 0.049 13.8 0.8 14 6.0 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-LITAF-like PF10601.9 AJZ76190.1 - 0.051 13.8 2.0 3.2 8.1 2.0 2.3 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain JTB PF05439.12 AJZ76190.1 - 0.057 13.5 0.2 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) zf-C6H2 PF15801.5 AJZ76190.1 - 0.067 13.5 1.0 0.88 9.9 0.1 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding HypA PF01155.19 AJZ76190.1 - 0.13 12.3 0.2 0.24 11.4 0.2 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA YacG PF03884.14 AJZ76190.1 - 0.75 9.6 4.2 15 5.4 0.4 2.9 2 1 1 3 3 3 0 DNA gyrase inhibitor YacG N6_Mtase PF02384.16 AJZ76191.1 - 2.6e-66 224.0 0.0 3.5e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 AJZ76191.1 - 1e-14 55.3 0.1 5.5e-07 30.3 0.0 2.7 1 1 1 2 2 2 2 HsdM N-terminal domain UPF0020 PF01170.18 AJZ76191.1 - 0.00017 21.4 0.0 0.00036 20.3 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 AJZ76191.1 - 0.007 15.9 0.0 0.025 14.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Eco57I PF07669.11 AJZ76191.1 - 0.064 13.8 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 Eco57I restriction-modification methylase EcoEI_R_C PF08463.10 AJZ76192.1 - 5.7e-37 127.4 1.8 1.3e-36 126.2 1.8 1.7 1 0 0 1 1 1 1 EcoEI R protein C-terminal ResIII PF04851.15 AJZ76192.1 - 1.1e-35 123.1 0.0 2.7e-35 121.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 AJZ76192.1 - 1.6e-12 47.6 0.0 7.5e-12 45.4 0.0 2.0 1 1 0 1 1 1 1 SWI2/SNF2 ATPase HSDR_N PF04313.14 AJZ76192.1 - 5.2e-11 42.8 0.1 1.4e-09 38.2 0.1 2.7 1 1 1 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) DEAD PF00270.29 AJZ76192.1 - 2.4e-09 37.2 0.0 2.8e-08 33.7 0.0 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AJZ76192.1 - 3.3e-07 30.6 0.0 1.3e-06 28.7 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 AJZ76192.1 - 0.0042 16.6 0.0 0.0083 15.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein T2SSE PF00437.20 AJZ76192.1 - 0.0064 15.6 0.0 0.017 14.2 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein UvrD-helicase PF00580.21 AJZ76192.1 - 0.12 11.9 0.9 0.22 11.0 0.1 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 AJZ76192.1 - 0.14 11.7 0.0 0.56 9.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AlbA_2 PF04326.14 AJZ76193.1 - 5.8e-10 39.6 0.0 1.5e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Putative DNA-binding domain KfrA_N PF11740.8 AJZ76194.1 - 0.014 16.1 0.0 0.02 15.6 0.0 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term EcoR124_C PF12008.8 AJZ76194.1 - 0.015 14.9 0.8 0.022 14.4 0.8 1.4 1 1 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal FUSC PF04632.12 AJZ76195.1 - 0.092 11.3 1.2 0.097 11.2 1.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DHHC PF01529.20 AJZ76195.1 - 0.099 12.8 0.2 0.11 12.6 0.2 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF2207 PF09972.9 AJZ76195.1 - 0.13 11.0 0.6 0.14 10.9 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LRR19-TM PF15176.6 AJZ76195.1 - 0.2 11.7 0.1 0.22 11.5 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Glycophorin_A PF01102.18 AJZ76195.1 - 0.24 11.7 0.1 0.26 11.5 0.1 1.2 1 0 0 1 1 1 0 Glycophorin A TcpE PF12648.7 AJZ76196.1 - 0.037 14.6 1.7 0.043 14.3 1.7 1.1 1 0 0 1 1 1 0 TcpE family DUF5337 PF17272.2 AJZ76196.1 - 0.048 13.5 0.2 0.057 13.2 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5337) TMCO5 PF14992.6 AJZ76196.1 - 0.1 12.2 2.8 0.11 12.1 2.8 1.0 1 0 0 1 1 1 0 TMCO5 family DUF2207 PF09972.9 AJZ76196.1 - 0.15 10.8 1.1 0.15 10.8 1.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2116 PF09889.9 AJZ76197.1 - 0.0015 18.4 12.5 0.014 15.3 2.3 3.0 1 1 1 2 2 2 2 Uncharacterized protein containing a Zn-ribbon (DUF2116) Zn_ribbon_17 PF17120.5 AJZ76197.1 - 0.0054 16.3 1.2 0.0097 15.5 1.2 1.5 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type TF_Zn_Ribbon PF08271.12 AJZ76197.1 - 0.019 14.5 2.6 0.14 11.7 0.9 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding C1_1 PF00130.22 AJZ76197.1 - 0.028 14.3 2.7 0.27 11.2 0.3 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 AJZ76197.1 - 0.096 12.7 6.2 0.92 9.6 2.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon DUF3270 PF11674.8 AJZ76197.1 - 0.11 12.6 0.1 0.16 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Zf_RING PF16744.5 AJZ76197.1 - 0.18 12.0 3.4 0.43 10.7 0.7 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger Vps39_2 PF10367.9 AJZ76197.1 - 0.7 10.4 4.1 1.1 9.7 0.7 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF4428 PF14471.6 AJZ76197.1 - 1.5 8.8 6.9 7.6 6.5 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) DEAD PF00270.29 AJZ76198.1 - 6.1e-09 35.9 0.2 1.5e-08 34.7 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AJZ76198.1 - 1.4e-08 34.9 0.4 3.7e-08 33.6 0.4 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 AJZ76198.1 - 3e-08 33.0 0.4 1.9e-05 23.8 0.1 2.2 1 1 1 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.7 AJZ76198.1 - 1.9e-07 30.3 0.3 0.0044 16.0 0.1 2.4 1 1 0 2 2 2 2 AAA-like domain DUF2075 PF09848.9 AJZ76198.1 - 5.9e-07 29.1 0.1 9.1e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 AJZ76198.1 - 1e-06 29.0 0.3 2.5e-06 27.8 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AJZ76198.1 - 4.5e-06 26.5 0.0 8.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arg_repressor PF01316.21 AJZ76198.1 - 3.2e-05 23.6 0.1 8.7e-05 22.2 0.1 1.8 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain Pox_A32 PF04665.12 AJZ76198.1 - 3.9e-05 23.2 0.5 8.1e-05 22.2 0.5 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein FUR PF01475.19 AJZ76198.1 - 4.3e-05 23.7 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 Ferric uptake regulator family DUF87 PF01935.17 AJZ76198.1 - 5.7e-05 23.3 1.2 0.00018 21.7 0.2 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 AJZ76198.1 - 0.00034 19.8 0.1 0.00056 19.0 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 AJZ76198.1 - 0.00075 19.8 0.2 0.0017 18.7 0.2 1.5 1 0 0 1 1 1 1 AAA domain HTH_Tnp_Tc3_2 PF01498.18 AJZ76198.1 - 0.0015 18.7 0.1 0.0037 17.5 0.1 1.6 1 0 0 1 1 1 1 Transposase ATPase_2 PF01637.18 AJZ76198.1 - 0.0061 16.5 2.6 0.0099 15.8 0.5 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea HTH_DeoR PF08220.12 AJZ76198.1 - 0.0075 16.0 0.1 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain KTI12 PF08433.10 AJZ76198.1 - 0.0079 15.7 0.6 0.19 11.1 0.1 2.3 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 AJZ76198.1 - 0.0081 16.7 0.5 0.021 15.4 0.5 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AJZ76198.1 - 0.011 15.5 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.12 AJZ76198.1 - 0.012 14.2 1.2 0.58 8.7 0.2 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) HTH_20 PF12840.7 AJZ76198.1 - 0.013 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain RNA_helicase PF00910.22 AJZ76198.1 - 0.017 15.5 0.1 0.048 14.1 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.26 AJZ76198.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain HTH_24 PF13412.6 AJZ76198.1 - 0.021 14.4 0.4 0.094 12.3 0.4 2.2 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding Zeta_toxin PF06414.12 AJZ76198.1 - 0.03 13.6 0.1 0.071 12.4 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin MarR PF01047.22 AJZ76198.1 - 0.036 14.0 0.0 0.099 12.6 0.0 1.7 1 0 0 1 1 1 0 MarR family NTPase_1 PF03266.15 AJZ76198.1 - 0.037 14.0 0.6 0.098 12.6 0.6 1.7 1 0 0 1 1 1 0 NTPase HTH_12 PF08461.10 AJZ76198.1 - 0.04 13.9 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain ABC_tran PF00005.27 AJZ76198.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 AJZ76198.1 - 0.046 13.4 0.1 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein Pox_TAA1 PF03295.14 AJZ76198.1 - 0.057 13.3 0.1 0.24 11.3 0.0 2.1 2 0 0 2 2 1 0 Poxvirus trans-activator protein A1 C-terminal cobW PF02492.19 AJZ76198.1 - 0.065 12.8 1.3 0.18 11.4 1.1 1.9 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 AJZ76198.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 AJZ76198.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 AJZ76198.1 - 0.18 11.4 1.5 0.67 9.5 0.6 2.4 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain DUF5416 PF17437.2 AJZ76200.1 - 0.0036 17.1 5.9 0.38 10.5 1.1 2.1 1 1 0 2 2 2 2 Family of unknown function (DUF5416) DUF641 PF04859.12 AJZ76200.1 - 0.05 13.9 1.9 0.099 13.0 1.9 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Nanovirus_coat PF04660.12 AJZ76200.1 - 0.055 13.5 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Nanovirus coat protein HtaA PF04213.13 AJZ76200.1 - 0.13 12.8 0.2 0.22 12.0 0.1 1.3 1 1 0 1 1 1 0 Htaa Pox_A_type_inc PF04508.12 AJZ76200.1 - 0.13 12.1 0.8 47 4.1 0.0 3.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat UPF0767 PF15990.5 AJZ76201.1 - 0.055 13.6 0.4 0.096 12.8 0.4 1.3 1 0 0 1 1 1 0 UPF0767 family DUF2703 PF10865.8 AJZ76201.1 - 0.069 13.3 0.0 0.099 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) DpnI_C PF17726.1 AJZ76202.1 - 0.012 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Dam-replacing HTH domain DUF853 PF05872.12 AJZ76203.1 - 8.1e-08 31.3 0.0 0.0012 17.6 0.0 2.3 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) DUF87 PF01935.17 AJZ76203.1 - 1.5e-05 25.2 3.0 0.00028 21.0 0.0 3.4 4 1 0 4 4 4 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AJZ76203.1 - 0.0063 15.5 0.0 0.17 10.7 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 AJZ76203.1 - 0.007 15.7 0.0 0.15 11.3 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Syntaxin-6_N PF09177.11 AJZ76203.1 - 0.014 15.9 1.7 0.12 12.9 0.5 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal AAA_22 PF13401.6 AJZ76203.1 - 0.022 15.0 0.0 0.97 9.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 AJZ76203.1 - 0.03 13.3 2.0 3.9 6.3 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain DUF2408 PF10303.9 AJZ76203.1 - 0.049 14.2 5.9 0.076 13.6 0.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) LexA_DNA_bind PF01726.16 AJZ76203.1 - 0.051 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 LexA DNA binding domain DUF2096 PF09869.9 AJZ76203.1 - 0.052 13.6 0.2 0.21 11.7 0.2 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) ABC_tran_CTD PF16326.5 AJZ76203.1 - 0.064 13.5 0.7 1 9.7 0.3 3.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain ResIII PF04851.15 AJZ76203.1 - 0.069 13.1 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 AJZ76203.1 - 0.11 12.0 0.1 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 AJZ76203.1 - 0.12 12.8 0.0 0.4 11.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase HTH_27 PF13463.6 AJZ76203.1 - 0.16 12.5 0.0 0.47 11.0 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF1292 PF06949.11 AJZ76204.1 - 4.7 8.2 8.0 16 6.5 5.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1292) EMP24_GP25L PF01105.24 AJZ76205.1 - 0.0019 18.2 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4369 PF14289.6 AJZ76205.1 - 0.021 15.3 0.1 0.031 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) YjcQ PF09639.10 AJZ76206.1 - 0.054 13.7 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 YjcQ protein TrmB PF01978.19 AJZ76206.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 AJZ76206.1 - 0.096 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) YdjM PF04307.14 AJZ76207.1 - 1.4e-08 34.3 7.8 1.8e-08 33.9 7.8 1.2 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase DUF5079 PF16882.5 AJZ76207.1 - 0.097 12.5 0.3 0.097 12.5 0.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5079) Thioredoxin PF00085.20 AJZ76208.1 - 2.4e-26 91.7 0.2 2.8e-26 91.5 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AJZ76208.1 - 1.6e-08 34.9 0.2 4.4e-08 33.5 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 AJZ76208.1 - 0.00029 20.8 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_8 PF13905.6 AJZ76208.1 - 0.0028 17.9 0.1 0.0094 16.3 0.1 1.8 1 1 1 2 2 2 1 Thioredoxin-like DUF953 PF06110.11 AJZ76208.1 - 0.0035 16.9 0.1 0.0055 16.3 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) AhpC-TSA PF00578.21 AJZ76208.1 - 0.011 15.6 0.2 0.02 14.8 0.2 1.4 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 AJZ76208.1 - 0.012 15.3 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 AJZ76208.1 - 0.023 14.4 0.1 0.024 14.3 0.1 1.2 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 AJZ76208.1 - 0.025 14.8 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin HyaE PF07449.11 AJZ76208.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF836 PF05768.14 AJZ76208.1 - 0.078 13.4 0.0 0.14 12.6 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_7 PF13899.6 AJZ76208.1 - 0.081 13.1 0.9 0.12 12.6 0.3 1.6 2 0 0 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 AJZ76208.1 - 0.1 11.9 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DSBA PF01323.20 AJZ76208.1 - 0.15 11.8 0.9 1.7 8.3 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain PMSR PF01625.21 AJZ76209.1 - 2.3e-66 222.7 0.5 2.5e-66 222.6 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Ferritin PF00210.24 AJZ76210.1 - 9.7e-34 116.3 0.7 1.1e-33 116.2 0.7 1.0 1 0 0 1 1 1 1 Ferritin-like domain Osmo_CC PF08946.10 AJZ76210.1 - 0.042 14.1 0.1 0.098 12.9 0.1 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF2024 PF09630.10 AJZ76211.1 - 3.1e-34 116.7 1.4 3.6e-34 116.5 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) Haem_bd PF14376.6 AJZ76211.1 - 0.08 12.9 0.1 0.095 12.6 0.1 1.2 1 0 0 1 1 1 0 Haem-binding domain Pyr_redox_2 PF07992.14 AJZ76212.1 - 1.7e-46 158.8 2.3 2e-46 158.6 2.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AJZ76212.1 - 2.1e-19 69.9 2.6 2.2e-15 56.7 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJZ76212.1 - 1.4e-16 60.8 6.3 6.3e-14 52.3 0.3 3.3 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 AJZ76212.1 - 1.3e-08 35.2 0.4 0.00042 20.7 0.1 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.19 AJZ76212.1 - 1.9e-05 24.1 0.1 0.00033 20.0 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AJZ76212.1 - 0.00028 21.0 0.3 0.00095 19.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AJZ76212.1 - 0.00036 20.2 9.1 0.2 11.2 1.0 3.8 3 1 2 5 5 5 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AJZ76212.1 - 0.00044 19.4 4.1 0.0017 17.5 1.9 2.8 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 AJZ76212.1 - 0.0011 18.1 6.1 0.17 10.9 0.0 4.0 3 1 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.17 AJZ76212.1 - 0.0012 18.1 0.8 0.19 11.0 0.2 3.2 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.20 AJZ76212.1 - 0.0031 17.6 0.9 0.4 10.7 0.0 3.1 2 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 AJZ76212.1 - 0.0085 16.1 1.2 2.7 7.9 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 AJZ76212.1 - 0.013 14.2 6.3 0.17 10.6 0.2 3.4 5 0 0 5 5 5 0 HI0933-like protein YtfJ_HI0045 PF09695.10 AJZ76212.1 - 0.042 13.5 0.1 0.082 12.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) FAD_oxidored PF12831.7 AJZ76212.1 - 0.11 11.8 3.5 0.26 10.6 0.1 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AJZ76212.1 - 0.3 10.4 1.9 12 5.1 0.3 2.8 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain BLOC1_2 PF10046.9 AJZ76213.1 - 0.0089 16.3 1.9 0.011 16.0 1.9 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 RHH_1 PF01402.21 AJZ76214.1 - 0.088 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family HicB PF05534.12 AJZ76214.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 HicB family SelR PF01641.18 AJZ76215.1 - 4.6e-55 184.9 0.2 5.3e-55 184.7 0.2 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 AJZ76215.1 - 0.00075 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Myb_DNA-bind_7 PF15963.5 AJZ76215.1 - 0.017 15.0 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 Myb DNA-binding like Zn_Tnp_IS1595 PF12760.7 AJZ76215.1 - 0.022 14.7 0.6 0.44 10.5 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF678 PF05077.12 AJZ76215.1 - 0.062 13.4 0.4 10 6.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) zf-ribbon_3 PF13248.6 AJZ76215.1 - 0.22 11.0 2.0 8.3 6.0 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain LPG_synthase_TM PF03706.13 AJZ76217.1 - 0.02 14.4 0.2 0.028 14.0 0.2 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region NAD_binding_6 PF08030.12 AJZ76217.1 - 0.037 14.2 0.5 0.05 13.7 0.5 1.2 1 0 0 1 1 1 0 Ferric reductase NAD binding domain HECW_N PF16562.5 AJZ76217.1 - 0.08 12.7 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 CHD5 PF04420.14 AJZ76217.1 - 0.54 10.1 0.1 0.54 10.1 0.1 2.9 2 1 1 3 3 3 0 CHD5-like protein Occludin_ELL PF07303.13 AJZ76217.1 - 0.94 10.2 4.4 10 6.9 0.6 2.4 3 0 0 3 3 3 0 Occludin homology domain Pentapeptide PF00805.22 AJZ76218.1 - 3e-84 276.0 96.9 1.7e-13 49.9 3.3 13.9 3 3 9 15 15 15 14 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AJZ76218.1 - 9.5e-55 182.7 31.4 7.3e-12 45.3 0.0 8.7 2 2 8 10 10 10 10 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AJZ76218.1 - 6.4e-39 131.9 23.9 2.9e-07 30.6 0.1 11.5 2 2 10 12 12 12 10 Pentapeptide repeats (9 copies) CfAFP PF05264.11 AJZ76218.1 - 1.3e-05 25.2 12.8 1.9 8.5 0.3 5.7 1 1 5 7 7 7 4 Choristoneura fumiferana antifreeze protein (CfAFP) Novirhabdo_Nv PF05554.11 AJZ76218.1 - 0.093 12.5 10.2 11 5.8 0.3 5.0 2 1 1 4 4 4 0 Viral hemorrhagic septicemia virus non-virion protein DUF285 PF03382.14 AJZ76218.1 - 2.3 8.0 17.4 8.6 6.1 2.7 4.3 3 1 0 3 3 3 0 Mycoplasma protein of unknown function, DUF285 CemA PF03040.14 AJZ76219.1 - 0.0031 17.5 0.8 0.0032 17.4 0.8 1.0 1 0 0 1 1 1 1 CemA family PhoU PF01895.19 AJZ76220.1 - 1.3e-17 64.0 4.1 1e-08 35.5 0.0 2.2 2 0 0 2 2 2 2 PhoU domain Glyco_transf_36 PF06165.11 AJZ76220.1 - 0.0081 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 36 DUF1308 PF07000.11 AJZ76220.1 - 0.01 15.8 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1308) BPD_transp_1 PF00528.22 AJZ76221.1 - 4.5e-17 62.4 20.4 4.5e-17 62.4 20.4 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component PhoU PF01895.19 AJZ76222.1 - 7.9e-16 58.3 12.9 1.7e-14 54.0 4.9 2.7 2 0 0 2 2 2 2 PhoU domain MazE_antitoxin PF04014.18 AJZ76222.1 - 2.8e-05 23.9 0.0 6.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin RPN6_N PF18055.1 AJZ76222.1 - 0.053 13.9 3.0 0.14 12.5 3.0 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain Methyltransf_25 PF13649.6 AJZ76224.1 - 6.5e-15 55.6 0.0 1.1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJZ76224.1 - 8.8e-13 48.7 0.0 1.5e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJZ76224.1 - 2.1e-10 40.6 0.0 2.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJZ76224.1 - 6.2e-07 30.1 0.0 1.3e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJZ76224.1 - 1.9e-06 27.8 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 AJZ76224.1 - 0.0013 18.3 0.6 0.04 13.4 0.3 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.11 AJZ76224.1 - 0.0059 16.2 0.0 0.0078 15.8 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 AJZ76224.1 - 0.0085 15.4 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF4263 PF14082.6 AJZ76224.1 - 0.014 15.6 0.3 0.018 15.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) MetW PF07021.12 AJZ76224.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 AJZ76224.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Aminotran_4 PF01063.19 AJZ76225.1 - 2.5e-51 174.7 0.0 2.9e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV AA_kinase PF00696.28 AJZ76227.1 - 9.7e-24 84.3 0.1 3e-23 82.7 0.1 1.8 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 AJZ76227.1 - 0.08 12.7 1.0 0.2 11.4 1.0 1.6 1 0 0 1 1 1 0 ACT domain Glyco_tran_28_C PF04101.16 AJZ76228.1 - 1.2e-14 54.7 0.1 2.8e-14 53.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 AJZ76228.1 - 7.3e-05 22.2 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 1 CCDC117 PF15810.5 AJZ76228.1 - 0.00031 21.1 0.1 0.00049 20.4 0.1 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 117 Laminin_G_3 PF13385.6 AJZ76229.1 - 6.7e-12 45.8 0.4 1.2e-10 41.8 0.4 2.1 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF900 PF05990.12 AJZ76230.1 - 3.2e-14 53.0 0.1 5.3e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 AJZ76230.1 - 2.2e-07 30.4 0.9 2.9e-06 26.7 0.9 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 AJZ76230.1 - 0.0021 18.1 0.9 0.0053 16.7 0.0 2.0 2 0 0 2 2 2 1 Cutinase LCAT PF02450.15 AJZ76230.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 AJZ76230.1 - 0.025 14.3 0.4 0.054 13.2 0.4 1.4 1 0 0 1 1 1 0 PGAP1-like protein NHL PF01436.21 AJZ76230.1 - 0.031 14.3 0.2 0.23 11.6 0.1 2.5 2 0 0 2 2 2 0 NHL repeat Lipase_2 PF01674.18 AJZ76230.1 - 0.049 13.1 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) SBBP PF06739.11 AJZ76230.1 - 0.67 10.0 4.1 4.9 7.2 0.0 3.7 4 0 0 4 4 4 0 Beta-propeller repeat MarR_2 PF12802.7 AJZ76231.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.6 2 0 0 2 2 2 0 MarR family DUF4423 PF14394.6 AJZ76231.1 - 0.019 14.7 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) RuvB_C PF05491.13 AJZ76231.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain HTH_Crp_2 PF13545.6 AJZ76231.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AJZ76231.1 - 0.09 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 AJZ76231.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 MarR family Guanylate_cyc PF00211.20 AJZ76233.1 - 7.9e-05 22.3 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Calx-beta PF03160.14 AJZ76234.1 - 3.9e-11 43.0 0.0 1.5e-08 34.7 0.0 2.9 2 0 0 2 2 2 2 Calx-beta domain TSP_3 PF02412.18 AJZ76234.1 - 7.9e-08 31.9 19.2 3.6e-07 29.8 7.7 4.9 4 1 0 4 4 4 2 Thrombospondin type 3 repeat LBR_tudor PF09465.10 AJZ76234.1 - 0.00061 19.5 0.0 0.07 12.9 0.0 2.6 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain POLO_box PF00659.18 AJZ76234.1 - 0.08 13.1 0.0 0.28 11.4 0.0 2.0 1 0 0 1 1 1 0 POLO box duplicated region Cas_Cas6 PF01881.16 AJZ76234.1 - 0.64 10.6 2.5 0.44 11.1 0.1 1.9 2 0 0 2 2 2 0 CRISPR associated protein Cas6 CDC45 PF02724.14 AJZ76234.1 - 7.1 4.8 13.5 14 3.9 13.5 1.4 1 0 0 1 1 1 0 CDC45-like protein Calx-beta PF03160.14 AJZ76236.1 - 6.2e-25 87.3 17.4 0.035 14.3 0.0 12.8 13 4 0 13 13 13 7 Calx-beta domain HYR PF02494.16 AJZ76236.1 - 9.6e-07 29.0 28.1 1.9 8.9 0.4 7.4 9 0 0 9 9 9 5 HYR domain DUF4115 PF13464.6 AJZ76236.1 - 0.00023 21.3 2.1 1.3e+02 2.8 0.0 5.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4115) ADPRTs_Tse2 PF18648.1 AJZ76236.1 - 0.11 12.6 6.2 1.1e+02 2.8 0.1 4.9 4 0 0 4 4 4 0 Tse2 ADP-ribosyltransferase toxins DUF2341 PF10102.9 AJZ76236.1 - 0.25 11.9 18.6 63 4.3 0.2 5.6 5 0 0 5 5 5 0 Domain of unknown function (DUF2341) Neur_chan_memb PF02932.16 AJZ76237.1 - 0.24 11.4 1.0 0.38 10.8 1.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HemX PF04375.14 AJZ76238.1 - 0.0014 18.0 1.6 0.0015 17.9 1.6 1.0 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase ABC_tran_CTD PF16326.5 AJZ76238.1 - 0.0044 17.2 3.1 0.11 12.7 0.3 2.2 1 1 0 2 2 2 1 ABC transporter C-terminal domain ATG16 PF08614.11 AJZ76238.1 - 0.0048 17.1 2.8 0.006 16.8 2.8 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 AJZ76238.1 - 0.0065 16.8 4.4 0.49 10.8 1.2 2.2 2 0 0 2 2 2 1 Csm1 N-terminal domain Spectrin PF00435.21 AJZ76238.1 - 0.011 16.3 0.8 0.014 15.9 0.8 1.1 1 0 0 1 1 1 0 Spectrin repeat FlaC_arch PF05377.11 AJZ76238.1 - 0.012 16.0 4.0 0.36 11.3 2.2 2.5 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Cob_adeno_trans PF01923.18 AJZ76238.1 - 0.013 15.6 0.2 0.017 15.3 0.2 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase PRKG1_interact PF15898.5 AJZ76238.1 - 0.02 15.8 3.3 0.028 15.3 3.3 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4140 PF13600.6 AJZ76238.1 - 0.021 15.3 2.4 0.6 10.6 0.1 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 AJZ76238.1 - 0.022 13.9 2.7 0.027 13.6 2.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlxA PF14282.6 AJZ76238.1 - 0.025 14.6 11.6 0.8 9.7 1.9 2.2 1 1 1 2 2 2 0 FlxA-like protein TMF_TATA_bd PF12325.8 AJZ76238.1 - 0.027 14.7 2.8 0.049 13.9 2.8 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Swi5 PF07061.11 AJZ76238.1 - 0.029 14.4 1.7 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Swi5 KCNQ_channel PF03520.14 AJZ76238.1 - 0.03 14.1 0.7 0.039 13.8 0.7 1.1 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel Vps53_N PF04100.12 AJZ76238.1 - 0.05 12.6 1.4 1.9 7.4 0.0 2.0 2 0 0 2 2 2 0 Vps53-like, N-terminal CENP-H PF05837.12 AJZ76238.1 - 0.052 14.0 2.2 0.071 13.5 2.2 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TolA_bind_tri PF16331.5 AJZ76238.1 - 0.057 13.5 6.4 1.1 9.4 1.5 2.1 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF2802 PF10975.8 AJZ76238.1 - 0.058 13.5 2.0 3.9 7.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DUF2730 PF10805.8 AJZ76238.1 - 0.062 13.4 1.5 0.2 11.8 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Lzipper-MIP1 PF14389.6 AJZ76238.1 - 0.066 13.5 1.7 0.11 12.8 1.7 1.4 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Plasmid_RAQPRD PF09686.10 AJZ76238.1 - 0.073 13.3 0.6 1.4 9.1 0.1 2.1 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) SOGA PF11365.8 AJZ76238.1 - 0.08 14.1 2.3 0.13 13.4 2.3 1.3 1 1 0 1 1 1 0 Protein SOGA LapA_dom PF06305.11 AJZ76238.1 - 0.08 12.8 1.6 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TssO PF17561.2 AJZ76238.1 - 0.096 12.8 2.8 0.35 11.0 2.7 1.7 1 1 0 1 1 1 0 Type VI secretion system, TssO bZIP_2 PF07716.15 AJZ76238.1 - 0.1 12.7 3.1 1.3 9.2 0.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper CLZ PF16526.5 AJZ76238.1 - 0.13 12.7 4.3 4.7 7.6 0.1 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GreA_GreB_N PF03449.15 AJZ76238.1 - 0.14 12.3 1.6 0.72 10.0 1.6 1.9 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal Viral_Beta_CD PF04530.12 AJZ76238.1 - 0.15 12.4 0.3 0.32 11.3 0.2 1.6 1 1 1 2 2 2 0 Viral Beta C/D like family HR1 PF02185.16 AJZ76238.1 - 0.16 12.1 4.0 6.7 6.9 0.2 2.2 2 0 0 2 2 2 0 Hr1 repeat DivIC PF04977.15 AJZ76238.1 - 0.2 11.4 7.1 2 8.2 0.4 2.2 1 1 1 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 AJZ76238.1 - 0.21 12.1 6.1 58 4.2 6.1 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 AJZ76238.1 - 0.22 12.0 5.9 1.2 9.6 1.3 2.5 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Med9 PF07544.13 AJZ76238.1 - 0.22 11.6 3.7 3.3 7.8 0.7 2.1 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Mito_fiss_reg PF05308.11 AJZ76238.1 - 0.29 11.2 5.6 0.33 11.0 2.8 1.8 1 1 1 2 2 2 0 Mitochondrial fission regulator DUF4349 PF14257.6 AJZ76238.1 - 0.29 10.6 4.4 3.6 7.0 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF5320 PF17253.2 AJZ76238.1 - 0.34 12.0 3.0 13 6.9 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5320) SlyX PF04102.12 AJZ76238.1 - 0.35 11.5 3.6 5.4 7.7 0.4 2.3 1 1 1 2 2 2 0 SlyX bZIP_1 PF00170.21 AJZ76238.1 - 0.45 10.6 3.3 1.5 9.0 0.8 2.1 2 0 0 2 2 2 0 bZIP transcription factor HALZ PF02183.18 AJZ76238.1 - 0.57 10.4 3.5 12 6.2 0.2 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc24 PF08286.11 AJZ76238.1 - 0.96 9.7 6.0 8.6 6.7 0.4 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF5339 PF17274.2 AJZ76238.1 - 1.8 9.4 4.9 7.6 7.5 0.6 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5339) DASH_Hsk3 PF08227.11 AJZ76238.1 - 1.9 8.9 7.1 12 6.4 2.8 2.7 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like DUF4407 PF14362.6 AJZ76238.1 - 2.9 7.1 6.7 1 8.6 3.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) 4HBT PF03061.22 AJZ76239.1 - 2.9e-16 59.6 0.0 4.2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 AJZ76239.1 - 0.0048 16.5 0.0 0.013 15.1 0.1 1.6 2 0 0 2 2 2 1 MaoC like domain Acyl_transf_3 PF01757.22 AJZ76241.1 - 0.22 10.5 27.0 0.29 10.1 11.0 2.4 1 1 2 3 3 3 0 Acyltransferase family Radical_SAM PF04055.21 AJZ76243.1 - 7e-17 62.3 0.0 1.8e-16 61.0 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily HTH_5 PF01022.20 AJZ76244.1 - 5.8e-07 29.3 0.5 2e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AJZ76244.1 - 0.00016 21.7 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain B-block_TFIIIC PF04182.12 AJZ76244.1 - 0.00042 20.4 0.0 0.00068 19.7 0.0 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 AJZ76244.1 - 0.0011 18.5 0.5 0.0032 17.0 0.2 1.9 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding DprA_WH PF17782.1 AJZ76244.1 - 0.0048 17.0 0.0 0.0068 16.5 0.0 1.1 1 0 0 1 1 1 1 DprA winged helix domain HTH_11 PF08279.12 AJZ76244.1 - 0.0049 16.8 0.1 0.0088 16.0 0.1 1.5 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 AJZ76244.1 - 0.013 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 AJZ76244.1 - 0.016 15.1 0.2 0.03 14.2 0.1 1.5 2 0 0 2 2 2 0 MarR family HTH_1 PF00126.27 AJZ76244.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AJZ76244.1 - 0.05 13.5 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 MarR family DUF3781 PF12636.7 AJZ76244.1 - 0.059 13.3 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) HTH_45 PF14947.6 AJZ76244.1 - 0.083 12.9 0.4 0.13 12.3 0.3 1.4 1 1 0 1 1 1 0 Winged helix-turn-helix DUF2517 PF10725.9 AJZ76245.1 - 0.23 11.3 1.5 0.34 10.7 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2517) Tetraspanin PF00335.20 AJZ76245.1 - 4.6 6.9 9.1 5.6 6.6 9.1 1.1 1 0 0 1 1 1 0 Tetraspanin family DS PF01916.17 AJZ76246.1 - 4.3e-72 242.8 0.0 4.9e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DS PF01916.17 AJZ76247.1 - 3.6e-93 312.0 0.3 4.1e-93 311.8 0.3 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Usp PF00582.26 AJZ76248.1 - 8.2e-18 65.3 0.0 9.1e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family S6PP_C PF08472.10 AJZ76248.1 - 0.023 14.6 0.1 0.06 13.2 0.1 1.6 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal THF_DHG_CYH PF00763.23 AJZ76248.1 - 0.024 14.9 0.1 4 7.7 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain TPR_1 PF00515.28 AJZ76249.1 - 2e-64 210.9 25.0 7.4e-11 41.4 0.0 9.3 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 AJZ76249.1 - 3.8e-51 167.1 20.3 4.1e-09 35.9 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 AJZ76249.1 - 6.4e-46 150.7 23.3 7.8e-07 28.8 0.0 9.5 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_17 PF13431.6 AJZ76249.1 - 3.3e-42 139.9 16.8 4.5e-07 29.8 0.1 9.6 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 AJZ76249.1 - 1.3e-35 120.8 21.3 1.3e-10 40.8 0.0 8.4 7 1 2 9 9 9 5 TPR repeat TPR_16 PF13432.6 AJZ76249.1 - 3.4e-33 114.0 0.0 9.3e-07 29.4 0.0 5.6 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 AJZ76249.1 - 5.9e-31 104.5 0.1 0.0045 17.7 0.0 8.9 2 2 7 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 AJZ76249.1 - 2e-29 101.9 7.6 1.4e-05 25.5 0.0 6.0 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 AJZ76249.1 - 4.7e-26 90.9 14.0 2e-07 31.2 0.0 7.1 2 2 4 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 AJZ76249.1 - 3.1e-25 86.3 3.7 0.031 14.3 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 AJZ76249.1 - 1.3e-17 63.8 11.1 3.2e-07 30.5 0.1 4.2 2 2 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 AJZ76249.1 - 2.1e-17 62.9 16.4 0.0015 18.6 0.1 7.9 6 2 2 9 9 9 4 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 AJZ76249.1 - 2.2e-17 62.4 8.4 0.025 15.2 0.0 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 AJZ76249.1 - 8.4e-14 50.9 9.7 1.2 9.1 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 AJZ76249.1 - 1.4e-13 50.8 0.1 0.0049 17.0 0.0 4.5 3 2 1 4 4 4 3 Tetratricopeptide repeat NARP1 PF12569.8 AJZ76249.1 - 1.8e-09 37.1 2.9 0.018 13.9 0.4 4.5 1 1 4 5 5 5 4 NMDA receptor-regulated protein 1 Coatomer_E PF04733.14 AJZ76249.1 - 5e-09 36.0 0.3 0.042 13.3 0.0 3.8 1 1 3 4 4 4 2 Coatomer epsilon subunit DUF4919 PF16266.5 AJZ76249.1 - 3e-08 33.8 2.3 0.29 11.1 0.0 4.8 3 2 2 5 5 5 2 Domain of unknown function (DUF4919) SRP_TPR_like PF17004.5 AJZ76249.1 - 1e-06 28.7 6.6 0.0074 16.3 0.0 4.2 2 2 2 4 4 4 2 Putative TPR-like repeat DUF3856 PF12968.7 AJZ76249.1 - 1.7e-06 28.1 2.0 0.083 13.0 0.1 5.2 3 3 1 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_20 PF14561.6 AJZ76249.1 - 2e-06 28.0 1.4 4.4 7.7 0.0 5.0 2 2 4 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 AJZ76249.1 - 3e-05 23.4 0.1 0.75 8.9 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 AJZ76249.1 - 3.5e-05 23.8 13.4 0.1 12.7 0.2 6.9 7 1 1 8 8 7 1 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.12 AJZ76249.1 - 4.9e-05 23.2 2.3 1.9 8.2 0.0 5.3 3 2 2 5 5 4 1 Plant specific mitochondrial import receptor subunit TOM20 PPR PF01535.20 AJZ76249.1 - 0.00021 21.3 4.0 13 6.3 0.0 6.0 6 0 0 6 6 6 0 PPR repeat NRBF2_MIT PF17169.4 AJZ76249.1 - 0.0016 18.6 0.2 8.7 6.7 0.0 3.9 3 1 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 DUF5113 PF17140.4 AJZ76249.1 - 0.0068 16.2 7.3 13 5.5 0.1 5.4 3 2 1 6 6 6 0 Domain of unknown function (DUF5113) Alkyl_sulf_dimr PF14863.6 AJZ76249.1 - 0.01 16.3 0.5 29 5.1 0.0 4.3 2 2 1 3 3 3 0 Alkyl sulfatase dimerisation TPR_21 PF09976.9 AJZ76249.1 - 0.023 14.4 0.9 9.1 5.9 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain HTH_Bact PF18768.1 AJZ76249.1 - 0.03 13.9 4.8 27 4.4 0.0 5.8 4 1 2 6 6 6 0 Helix-turn-helix bacterial domain SPO22 PF08631.10 AJZ76249.1 - 0.031 13.8 2.6 19 4.6 0.0 4.5 2 2 3 5 5 5 0 Meiosis protein SPO22/ZIP4 like Rapsyn_N PF10579.9 AJZ76249.1 - 0.043 13.9 0.3 1.8 8.7 0.0 3.2 2 1 0 3 3 2 0 Rapsyn N-terminal myristoylation and linker region HrpB1_HrpK PF09613.10 AJZ76249.1 - 0.11 12.1 0.0 13 5.4 0.0 3.0 1 1 2 4 4 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_MalT PF17874.1 AJZ76249.1 - 0.19 11.1 0.1 9.5 5.5 0.2 3.1 2 1 0 2 2 2 0 MalT-like TPR region PPTA PF01239.22 AJZ76249.1 - 0.25 11.1 9.8 23 4.9 0.0 6.1 8 0 0 8 8 6 0 Protein prenyltransferase alpha subunit repeat DUF3378 PF11858.8 AJZ76250.1 - 0.062 13.4 0.6 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) ApoC-I PF04691.12 AJZ76250.1 - 0.79 9.7 4.2 4.3 7.3 0.2 2.6 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) YvbH_ext PF11724.8 AJZ76250.1 - 4.1 7.8 7.3 1.4 9.2 1.0 2.6 1 1 1 2 2 2 0 YvbH-like oligomerisation region Urease_gamma PF00547.18 AJZ76252.1 - 9.3e-13 48.3 0.1 1.1e-12 48.1 0.1 1.1 1 0 0 1 1 1 1 Urease, gamma subunit NicO PF03824.16 AJZ76253.1 - 1.3e-07 31.3 15.2 0.0005 19.5 1.7 2.2 1 1 1 2 2 2 2 High-affinity nickel-transport protein Phage_holin_3_6 PF07332.11 AJZ76253.1 - 1.7 8.7 7.2 19 5.4 0.0 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III JSRP PF15312.6 AJZ76254.1 - 0.17 11.8 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein RVT_3 PF13456.6 AJZ76255.1 - 1.2e-10 41.2 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 AJZ76255.1 - 1.3e-08 35.2 0.0 1.4e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 RNase H SCP-1 PF05483.12 AJZ76255.1 - 0.12 10.3 0.0 0.14 10.2 0.0 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) ATP-grasp_5 PF13549.6 AJZ76256.1 - 2e-79 266.1 1.0 2e-79 266.1 1.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.6 AJZ76256.1 - 3.8e-54 182.2 0.6 1e-53 180.8 0.6 1.8 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AJZ76256.1 - 9.7e-23 80.9 0.2 5.3e-22 78.5 0.1 2.3 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.19 AJZ76256.1 - 3.1e-08 34.2 3.3 6.5e-08 33.1 1.3 2.6 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.10 AJZ76256.1 - 7.4e-05 22.4 0.5 0.00016 21.3 0.5 1.7 1 0 0 1 1 1 1 ATP-grasp domain DUF166 PF02593.14 AJZ76256.1 - 0.00087 18.9 0.1 0.0028 17.2 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function Dak1_2 PF13684.6 AJZ76256.1 - 0.0092 15.1 0.1 0.023 13.8 0.1 1.6 1 0 0 1 1 1 1 Dihydroxyacetone kinase family CPSase_L_D2 PF02786.17 AJZ76256.1 - 0.039 13.5 0.2 0.078 12.5 0.2 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DZR PF12773.7 AJZ76257.1 - 0.00096 19.1 7.5 0.0072 16.3 7.5 1.9 1 1 0 1 1 1 1 Double zinc ribbon zinc-ribbons_6 PF07191.12 AJZ76257.1 - 0.0042 17.0 6.9 0.0058 16.6 6.9 1.3 1 0 0 1 1 1 1 zinc-ribbons zinc_ribbon_2 PF13240.6 AJZ76257.1 - 0.013 15.2 3.9 0.013 15.2 3.9 2.1 2 0 0 2 2 2 0 zinc-ribbon domain TackOD1 PF18551.1 AJZ76257.1 - 0.026 14.2 5.1 0.041 13.5 5.1 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 PolC_DP2 PF03833.13 AJZ76257.1 - 0.03 12.2 3.4 0.03 12.2 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-B_box PF00643.24 AJZ76257.1 - 0.034 14.3 2.5 0.034 14.3 2.5 2.1 2 0 0 2 2 2 0 B-box zinc finger Zn-ribbon_8 PF09723.10 AJZ76257.1 - 0.046 13.8 9.9 0.44 10.7 0.7 3.0 1 1 2 3 3 3 0 Zinc ribbon domain DUF1258 PF06869.12 AJZ76257.1 - 0.13 11.7 2.2 0.13 11.7 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) zf-C2H2 PF00096.26 AJZ76257.1 - 0.32 11.5 7.9 7 7.3 0.4 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 AJZ76257.1 - 0.38 10.2 7.8 5.7 6.5 3.3 2.7 2 1 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AJZ76257.1 - 0.42 10.6 9.0 3.5 7.6 9.0 2.3 1 1 0 1 1 1 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 AJZ76257.1 - 0.47 10.0 8.9 4 7.0 3.6 2.5 1 1 1 2 2 2 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 AJZ76257.1 - 0.63 10.2 6.3 1.1 9.5 1.2 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-CHY PF05495.12 AJZ76257.1 - 0.77 10.3 12.5 0.51 10.9 8.8 2.3 2 1 0 2 2 2 0 CHY zinc finger HypA PF01155.19 AJZ76257.1 - 0.93 9.5 8.1 4.4 7.4 8.3 1.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin_2 PF18073.1 AJZ76257.1 - 1 9.1 9.6 24 4.8 0.1 2.9 2 1 1 3 3 3 0 Rubredoxin metal binding domain C1_1 PF00130.22 AJZ76257.1 - 1.1 9.2 10.2 9.1 6.3 10.2 2.1 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF983 PF06170.12 AJZ76257.1 - 1.3 9.5 6.5 1.1e+02 3.3 6.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF983) C1_2 PF03107.16 AJZ76257.1 - 1.4 9.3 10.6 0.11 12.9 4.6 2.0 1 1 1 2 2 2 0 C1 domain Fer4_2 PF12797.7 AJZ76257.1 - 1.6 9.0 9.0 0.94 9.7 3.3 2.6 2 1 0 2 2 2 0 4Fe-4S binding domain Prok-RING_1 PF14446.6 AJZ76257.1 - 1.8 8.6 10.5 1.4 8.9 5.0 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_4 PF13717.6 AJZ76257.1 - 5.8 6.9 10.1 16 5.5 0.3 3.3 3 1 0 3 3 3 0 zinc-ribbon domain GATA PF00320.27 AJZ76257.1 - 6.9 6.4 9.6 8 6.2 3.8 2.9 2 1 0 2 2 2 0 GATA zinc finger HTH_5 PF01022.20 AJZ76258.1 - 2.6e-14 52.8 0.5 2.6e-14 52.8 0.5 1.6 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AJZ76258.1 - 1.7e-08 33.9 0.1 2.6e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AJZ76258.1 - 1.3e-06 28.3 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 AJZ76258.1 - 0.00029 20.7 0.1 0.00073 19.4 0.1 1.7 1 1 1 2 2 2 1 MarR family TFIIE_alpha PF02002.17 AJZ76258.1 - 0.00086 19.1 0.3 0.0011 18.8 0.3 1.2 1 0 0 1 1 1 1 TFIIE alpha subunit MarR_2 PF12802.7 AJZ76258.1 - 0.001 18.9 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AJZ76258.1 - 0.0049 16.7 0.0 0.0066 16.3 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 AJZ76258.1 - 0.006 16.4 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain Arg_repressor PF01316.21 AJZ76258.1 - 0.014 15.1 1.1 0.027 14.2 0.4 1.9 1 1 1 2 2 2 0 Arginine repressor, DNA binding domain HTH_34 PF13601.6 AJZ76258.1 - 0.021 15.0 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain Penicillinase_R PF03965.16 AJZ76258.1 - 0.023 15.0 0.1 0.031 14.6 0.1 1.3 1 0 0 1 1 1 0 Penicillinase repressor Swi5 PF07061.11 AJZ76258.1 - 0.074 13.1 0.1 0.096 12.8 0.1 1.2 1 0 0 1 1 1 0 Swi5 Dimerisation2 PF16864.5 AJZ76258.1 - 0.12 12.4 0.1 0.15 12.0 0.1 1.3 1 1 0 1 1 1 0 Dimerisation domain HTH_AsnC-type PF13404.6 AJZ76258.1 - 0.12 12.2 0.0 0.37 10.7 0.0 1.8 1 1 1 2 2 2 0 AsnC-type helix-turn-helix domain MIP PF00230.20 AJZ76259.1 - 4.2e-36 124.8 18.0 5e-36 124.5 18.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Adenine_glyco PF03352.13 AJZ76260.1 - 7.8e-80 266.8 0.2 9.3e-80 266.6 0.2 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase HpaB_N PF11794.8 AJZ76261.1 - 1.4e-92 310.3 0.0 3.9e-92 308.8 0.0 1.7 2 0 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 AJZ76261.1 - 5.8e-71 237.7 0.1 8.8e-71 237.2 0.1 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Amidohydro_1 PF01979.20 AJZ76262.1 - 5.5e-73 246.2 1.1 7.3e-73 245.8 1.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 AJZ76262.1 - 6.6e-52 174.9 4.3 1.9e-51 173.5 4.3 1.8 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 AJZ76262.1 - 1.1e-06 28.5 0.9 9.5e-05 22.0 0.1 2.6 2 1 0 2 2 2 2 Amidohydrolase family Urease_gamma PF00547.18 AJZ76263.1 - 1.3e-46 156.9 0.0 1.5e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Urease, gamma subunit UreE_N PF02814.15 AJZ76264.1 - 1.9e-07 30.6 0.0 3.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain NA37 PF04245.13 AJZ76264.1 - 0.052 13.0 0.7 0.089 12.2 0.5 1.4 2 0 0 2 2 2 0 37-kD nucleoid-associated bacterial protein UreF PF01730.16 AJZ76265.1 - 1.8e-21 77.1 0.0 2.1e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 UreF Protoglobin PF11563.8 AJZ76265.1 - 0.024 14.5 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 Protoglobin Tetraspanin PF00335.20 AJZ76265.1 - 0.047 13.4 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family cobW PF02492.19 AJZ76266.1 - 7.1e-31 107.2 0.0 8.4e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 AJZ76266.1 - 2e-09 36.8 1.0 9.8e-09 34.6 1.0 1.8 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 AJZ76266.1 - 1.5e-05 24.9 0.1 5.5e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 AJZ76266.1 - 0.0009 19.2 0.1 0.0018 18.2 0.1 1.7 1 1 0 1 1 1 1 NTPase MipZ PF09140.11 AJZ76266.1 - 0.0092 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ GTP_EFTU PF00009.27 AJZ76266.1 - 0.023 14.2 0.2 1.7 8.2 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CbiA PF01656.23 AJZ76266.1 - 0.033 14.3 0.0 0.042 13.9 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1_Xtn PF16897.5 AJZ76266.1 - 0.033 14.2 0.1 0.094 12.7 0.0 1.7 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_22 PF13401.6 AJZ76266.1 - 0.046 14.0 0.0 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AJZ76266.1 - 0.057 13.3 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 AJZ76266.1 - 0.064 13.0 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AJZ76266.1 - 0.073 13.0 0.2 15 5.5 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 AJZ76266.1 - 0.13 12.8 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_PrkA PF08298.11 AJZ76266.1 - 0.15 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_18 PF13238.6 AJZ76266.1 - 0.15 12.6 0.1 0.32 11.6 0.1 1.8 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 AJZ76266.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_33 PF13671.6 AJZ76266.1 - 0.18 11.9 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain UreD PF01774.17 AJZ76267.1 - 3.7e-43 147.9 0.0 4.5e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Ribosomal_L22e PF01776.17 AJZ76267.1 - 0.017 15.5 0.3 0.064 13.6 0.1 2.0 2 0 0 2 2 2 0 Ribosomal L22e protein family AdoHcyase PF05221.17 AJZ76267.1 - 0.02 14.1 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase Peptidase_S24 PF00717.23 AJZ76268.1 - 5.7e-09 35.8 0.5 1.3e-08 34.7 0.5 1.6 1 0 0 1 1 1 1 Peptidase S24-like MscL PF01741.18 AJZ76268.1 - 0.0035 17.6 1.5 0.0037 17.5 0.1 1.8 2 0 0 2 2 2 1 Large-conductance mechanosensitive channel, MscL DUF3299 PF11736.8 AJZ76268.1 - 0.0086 16.1 0.3 0.024 14.7 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3299) DUF4330 PF14221.6 AJZ76268.1 - 0.0093 16.2 1.3 0.36 11.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4330) PRC PF05239.16 AJZ76269.1 - 0.00012 22.1 0.4 0.00024 21.1 0.4 1.5 1 0 0 1 1 1 1 PRC-barrel domain DZR PF12773.7 AJZ76269.1 - 0.00047 20.1 9.7 0.04 13.9 3.2 2.7 2 1 0 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.6 AJZ76269.1 - 0.00048 19.7 4.4 0.00048 19.7 4.4 2.9 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 AJZ76269.1 - 0.0011 19.6 1.0 2 9.2 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon family zinc-ribbons_6 PF07191.12 AJZ76269.1 - 0.0066 16.4 1.2 21 5.2 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbons Prim_Zn_Ribbon PF08273.12 AJZ76269.1 - 0.0069 16.6 7.1 5.4 7.4 0.0 3.6 3 0 0 3 3 3 2 Zinc-binding domain of primase-helicase TF_Zn_Ribbon PF08271.12 AJZ76269.1 - 0.019 14.5 2.6 0.62 9.6 0.1 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding Gin PF10764.9 AJZ76269.1 - 0.24 11.4 5.4 7.2 6.6 0.1 3.1 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin A2L_zn_ribbon PF08792.10 AJZ76269.1 - 0.31 10.8 0.0 0.31 10.8 0.0 3.9 3 1 0 3 3 2 0 A2L zinc ribbon domain zinc_ribbon_11 PF11682.8 AJZ76269.1 - 0.42 10.6 3.7 16 5.5 0.2 3.1 2 1 1 3 3 3 0 Probable zinc-ribbon zf-CHY PF05495.12 AJZ76269.1 - 1.3 9.6 5.1 3.7 8.1 0.9 2.5 2 1 0 2 2 2 0 CHY zinc finger C1_2 PF03107.16 AJZ76269.1 - 1.5 9.2 7.1 56 4.2 0.1 3.4 3 0 0 3 3 3 0 C1 domain Nudix_N_2 PF14803.6 AJZ76269.1 - 5.2 7.1 8.8 3.6 7.6 0.5 3.1 3 0 0 3 3 3 0 Nudix N-terminal NOB1_Zn_bind PF08772.11 AJZ76269.1 - 5.4 7.3 9.5 14 6.0 3.2 3.1 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf_UBZ PF18439.1 AJZ76269.1 - 6.3 6.5 8.2 2.4 7.8 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 AJZ76269.1 - 6.9 6.2 11.8 0.67 9.4 1.7 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-dskA_traR PF01258.17 AJZ76269.1 - 7.6 6.6 7.3 4.5 7.3 0.1 2.7 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Thioredoxin PF00085.20 AJZ76270.1 - 1.6e-31 108.3 0.1 1.8e-31 108.2 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AJZ76270.1 - 2e-11 44.1 0.1 3.1e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 AJZ76270.1 - 2.9e-09 37.3 0.1 7.9e-09 35.9 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AJZ76270.1 - 6.1e-07 29.5 0.1 9.6e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 AJZ76270.1 - 1.3e-06 28.3 0.1 1.5e-06 28.1 0.1 1.0 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 AJZ76270.1 - 3e-05 24.0 0.1 3.6e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain Redoxin PF08534.10 AJZ76270.1 - 4.7e-05 23.1 0.1 6.6e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 AJZ76270.1 - 0.00018 21.4 0.0 0.00022 21.1 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 AJZ76270.1 - 0.0002 21.2 0.0 0.00023 21.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 AJZ76270.1 - 0.001 18.5 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF953 PF06110.11 AJZ76270.1 - 0.0038 16.8 0.4 0.0095 15.6 0.4 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) HyaE PF07449.11 AJZ76270.1 - 0.0041 17.1 0.1 0.0093 15.9 0.0 1.6 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 AJZ76270.1 - 0.028 14.6 0.1 0.25 11.5 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin DUF836 PF05768.14 AJZ76270.1 - 0.089 13.2 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 AJZ76270.1 - 0.094 13.0 0.1 0.16 12.2 0.1 1.4 1 1 0 1 1 1 0 Glutaredoxin zinc_ribbon_2 PF13240.6 AJZ76271.1 - 5e-07 29.2 3.3 7.4e-07 28.7 3.3 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AJZ76271.1 - 0.0003 20.7 1.5 0.00044 20.2 1.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 AJZ76271.1 - 0.00031 20.1 2.3 0.00053 19.3 2.3 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 AJZ76271.1 - 0.0069 17.1 0.1 0.013 16.3 0.1 1.4 1 0 0 1 1 1 1 zinc-ribbon family Sporozoite_P67 PF05642.11 AJZ76271.1 - 1.4 7.0 9.0 1.6 6.7 9.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nudix_N_2 PF14803.6 AJZ76271.1 - 3.6 7.6 6.6 2.1 8.3 1.4 2.2 2 0 0 2 2 2 0 Nudix N-terminal FAM25 PF15825.5 AJZ76272.1 - 0.008 16.5 0.1 0.015 15.6 0.1 1.6 1 0 0 1 1 1 1 FAM25 family Aminopep PF10023.9 AJZ76272.1 - 0.048 13.0 10.3 0.074 12.4 10.3 1.3 1 0 0 1 1 1 0 Putative aminopeptidase Spore_III_AB PF09548.10 AJZ76272.1 - 0.075 13.1 3.9 0.12 12.5 3.1 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) FbpA PF05833.11 AJZ76272.1 - 0.22 10.3 6.4 2 7.1 6.4 1.9 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) GrpE PF01025.19 AJZ76272.1 - 0.9 9.2 7.1 9.4 5.9 7.1 2.0 1 1 0 1 1 1 0 GrpE zinc_ribbon_2 PF13240.6 AJZ76273.1 - 1.9e-07 30.6 3.2 3.3e-07 29.8 3.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 AJZ76273.1 - 2.4e-06 26.7 1.5 3.9e-06 26.1 1.5 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AJZ76273.1 - 1.3e-05 25.1 0.5 1.8e-05 24.6 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 AJZ76273.1 - 0.00011 22.9 0.3 0.00014 22.6 0.3 1.2 1 0 0 1 1 1 1 zinc-ribbon family UPF0547 PF10571.9 AJZ76273.1 - 0.00022 21.2 3.8 0.00067 19.7 3.9 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.6 AJZ76273.1 - 0.002 18.0 4.7 0.17 11.8 0.2 2.4 2 0 0 2 2 2 2 Nudix N-terminal YhfH PF14149.6 AJZ76273.1 - 0.058 13.4 5.0 1.2 9.2 0.3 2.3 1 1 1 2 2 2 0 YhfH-like protein RNA_POL_M_15KD PF02150.16 AJZ76273.1 - 0.16 11.9 4.0 2.7 7.9 0.4 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf_UBZ PF18439.1 AJZ76273.1 - 0.16 11.5 3.8 0.42 10.2 0.2 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger A2L_zn_ribbon PF08792.10 AJZ76273.1 - 0.19 11.5 3.5 4.3 7.2 0.1 2.8 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-tcix PF14952.6 AJZ76273.1 - 0.19 11.3 1.8 1.7 8.3 0.2 2.2 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Mob_synth_C PF06463.13 AJZ76273.1 - 0.27 11.2 1.7 2 8.4 1.9 2.0 1 1 0 1 1 1 0 Molybdenum Cofactor Synthesis C HscB_4_cys PF18256.1 AJZ76273.1 - 0.35 10.7 1.9 7.1 6.5 0.1 2.3 1 1 1 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif HalOD2 PF18547.1 AJZ76273.1 - 0.43 10.5 2.6 11 6.0 0.1 2.2 1 1 1 2 2 2 0 Halobacterial output domain 2 zf-NADH-PPase PF09297.11 AJZ76273.1 - 0.8 9.4 4.9 20 4.9 4.9 2.3 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.11 AJZ76273.1 - 2.5 8.3 6.4 7.4 6.8 0.6 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like E1-E2_ATPase PF00122.20 AJZ76274.1 - 9.3e-58 194.7 0.4 2.2e-57 193.5 0.4 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AJZ76274.1 - 1e-45 156.7 3.1 1.7e-45 155.9 3.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AJZ76274.1 - 4.3e-25 87.9 0.7 3.1e-14 53.2 0.1 2.9 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AJZ76274.1 - 1.6e-06 28.0 5.6 2.1e-05 24.4 1.0 3.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AJZ76274.1 - 0.0062 16.6 1.3 0.14 12.3 0.0 3.4 3 1 1 4 4 4 1 Haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.6 AJZ76274.1 - 0.0082 16.6 0.3 0.056 13.9 0.1 2.5 3 0 0 3 3 3 1 CoA binding domain UPF0180 PF03698.13 AJZ76274.1 - 0.048 13.8 0.4 48 4.2 0.0 3.9 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0180) HAD_2 PF13419.6 AJZ76274.1 - 0.19 11.8 2.6 0.29 11.2 0.6 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF3487 PF11990.8 AJZ76274.1 - 1.7 8.5 3.9 2.7 7.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) AdoHcyase PF05221.17 AJZ76275.1 - 1.3e-54 185.4 0.0 2.2e-28 99.3 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AJZ76275.1 - 9.5e-50 168.8 1.7 1.7e-49 168.0 1.7 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 AJZ76275.1 - 5.3e-08 32.4 0.2 2.2e-07 30.4 0.3 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AJZ76275.1 - 4.5e-05 23.1 0.2 9.1e-05 22.1 0.2 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 AJZ76275.1 - 0.038 13.3 2.2 0.24 10.7 2.2 2.1 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amidohydro_1 PF01979.20 AJZ76276.1 - 2.3e-19 69.9 0.2 9.3e-19 67.9 0.2 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AJZ76276.1 - 8.2e-11 42.0 0.1 0.0001 22.0 0.0 3.2 2 1 2 4 4 4 2 Amidohydrolase family TatD_DNase PF01026.21 AJZ76276.1 - 0.00045 19.7 0.1 0.11 11.8 0.0 2.2 1 1 1 2 2 2 2 TatD related DNase AP_endonuc_2 PF01261.24 AJZ76276.1 - 0.0047 16.4 0.0 0.45 9.9 0.0 2.4 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel Rib_5-P_isom_A PF06026.14 AJZ76277.1 - 1e-54 184.8 0.1 1.2e-54 184.5 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 AJZ76277.1 - 7.7e-05 22.7 0.3 0.044 13.7 0.1 2.3 1 1 1 2 2 2 2 DeoR C terminal sensor domain BLACT_WH PF17778.1 AJZ76277.1 - 0.052 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain LUC7 PF03194.15 AJZ76278.1 - 6.4 6.4 9.4 11 5.6 3.3 2.4 2 0 0 2 2 2 0 LUC7 N_terminus LSM PF01423.22 AJZ76279.1 - 2.1e-23 81.8 0.2 2.3e-23 81.6 0.2 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 AJZ76279.1 - 0.083 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Creatininase PF02633.14 AJZ76280.1 - 4.3e-50 170.4 0.0 5e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase Formyl_trans_N PF00551.19 AJZ76281.1 - 6.5e-45 153.1 0.3 1.1e-44 152.4 0.1 1.4 2 0 0 2 2 2 1 Formyl transferase ACT_6 PF13740.6 AJZ76281.1 - 8e-08 32.2 0.1 2.1e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 AJZ76281.1 - 0.001 19.6 0.1 0.0033 18.0 0.1 1.9 1 0 0 1 1 1 1 ACT domain PrpR_N PF06506.11 AJZ76281.1 - 0.02 14.5 0.2 0.15 11.6 0.1 2.0 2 0 0 2 2 2 0 Propionate catabolism activator DEDD_Tnp_IS110 PF01548.17 AJZ76281.1 - 0.034 14.0 0.2 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Transposase Helicase_C PF00271.31 AJZ76281.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain YdjM PF04307.14 AJZ76282.1 - 0.02 14.2 6.1 0.054 12.8 6.1 1.8 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Phage_holin_2_3 PF16080.5 AJZ76282.1 - 0.066 13.0 1.2 6.7 6.5 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DUF5345 PF17280.2 AJZ76282.1 - 2.7 8.0 5.2 3.3 7.8 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5345) PGM_PMM_I PF02878.16 AJZ76283.1 - 1.1e-39 135.3 0.0 3.2e-39 133.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AJZ76283.1 - 1.4e-26 93.1 0.0 5.1e-26 91.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AJZ76283.1 - 2.4e-22 79.3 0.1 4.5e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AJZ76283.1 - 1.5e-11 44.3 0.0 3.5e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF2624 PF11116.8 AJZ76283.1 - 0.024 15.5 0.4 0.089 13.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) zf-met2 PF12907.7 AJZ76283.1 - 0.026 14.7 0.2 0.062 13.4 0.2 1.6 1 0 0 1 1 1 0 Zinc-binding Ribosomal_L7Ae PF01248.26 AJZ76284.1 - 1.4e-26 92.1 0.1 1.7e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 AJZ76284.1 - 0.057 13.3 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Ribosomal_S28e PF01200.18 AJZ76285.1 - 3.6e-28 97.3 3.7 4e-28 97.2 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_L24e PF01246.20 AJZ76286.1 - 8.7e-20 70.7 0.6 1e-19 70.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.14 AJZ76286.1 - 0.02 14.8 2.0 0.041 13.8 2.0 1.6 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF2256 PF10013.9 AJZ76286.1 - 0.028 14.5 5.5 5.1 7.3 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-FLZ PF04570.14 AJZ76286.1 - 0.053 13.0 0.1 0.088 12.3 0.1 1.4 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 NDK PF00334.19 AJZ76287.1 - 5.2e-51 172.2 0.1 5.8e-51 172.0 0.1 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Thioredoxin PF00085.20 AJZ76288.1 - 9.1e-29 99.5 0.0 1.5e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 AJZ76288.1 - 3.6e-09 36.5 0.1 4.4e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AJZ76288.1 - 4.3e-08 33.6 0.2 1.5e-07 31.9 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AJZ76288.1 - 7.3e-07 29.4 0.5 5.4e-05 23.4 0.0 2.4 2 1 1 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 AJZ76288.1 - 2.1e-06 27.3 0.1 2.8e-06 26.9 0.1 1.3 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 AJZ76288.1 - 2.1e-05 24.5 0.6 3.7e-05 23.6 0.6 1.5 1 1 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 AJZ76288.1 - 3.7e-05 23.5 0.1 0.00031 20.5 0.1 1.9 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AJZ76288.1 - 0.00046 20.1 0.0 0.00074 19.4 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.16 AJZ76288.1 - 0.00048 19.2 0.0 0.00057 18.9 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_3 PF13192.6 AJZ76288.1 - 0.00059 19.8 0.0 0.00096 19.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.6 AJZ76288.1 - 0.0085 16.2 0.7 0.018 15.2 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 AJZ76288.1 - 0.022 14.7 0.1 0.048 13.6 0.0 1.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 AJZ76288.1 - 0.025 14.5 0.0 0.036 14.0 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.24 AJZ76288.1 - 0.027 14.7 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_5 PF13743.6 AJZ76288.1 - 0.11 12.2 0.9 0.2 11.3 0.1 1.7 2 0 0 2 2 2 0 Thioredoxin DUF836 PF05768.14 AJZ76288.1 - 0.11 12.9 0.0 0.33 11.4 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) tRNA_bind PF01588.20 AJZ76288.1 - 0.12 12.5 0.1 0.25 11.5 0.0 1.5 2 0 0 2 2 1 0 Putative tRNA binding domain EF-1_beta_acid PF10587.9 AJZ76288.1 - 0.13 12.8 0.9 0.27 11.7 0.9 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Archease PF01951.16 AJZ76289.1 - 2.1e-33 115.5 2.0 2.3e-33 115.3 2.0 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) TOBE_3 PF12857.7 AJZ76289.1 - 0.027 14.4 0.0 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 TOBE-like domain tRNA-synt_His PF13393.6 AJZ76290.1 - 3.2e-42 144.9 0.0 3.9e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 AJZ76290.1 - 9.1e-12 45.3 0.0 1.5e-11 44.6 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AJZ76290.1 - 6.9e-09 35.7 0.0 2.3e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2d PF01409.20 AJZ76290.1 - 0.0066 16.0 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) eIF-6 PF01912.18 AJZ76291.1 - 1.3e-63 213.9 1.0 1.5e-63 213.7 1.0 1.0 1 0 0 1 1 1 1 eIF-6 family Fer4 PF00037.27 AJZ76292.1 - 2.4e-09 36.6 11.7 6.3e-06 25.8 1.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJZ76292.1 - 2.2e-08 34.6 3.3 0.00057 20.4 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AJZ76292.1 - 1.5e-07 32.2 12.5 1.4e-05 25.9 4.9 2.1 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AJZ76292.1 - 4.5e-07 29.9 5.0 1.5e-06 28.2 5.3 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AJZ76292.1 - 8.2e-07 29.4 2.7 0.0053 17.2 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJZ76292.1 - 1.2e-06 28.6 4.2 0.004 17.3 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJZ76292.1 - 3.2e-06 27.2 6.8 4.3e-05 23.6 7.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AJZ76292.1 - 4e-05 23.5 11.6 0.013 15.5 1.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AJZ76292.1 - 0.00023 21.4 4.9 0.032 14.7 0.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AJZ76292.1 - 0.00056 19.9 11.1 0.039 14.1 3.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AJZ76292.1 - 0.00094 19.4 7.1 0.002 18.3 4.8 2.2 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_13 PF13370.6 AJZ76292.1 - 0.001 19.5 10.4 0.066 13.8 0.8 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 AJZ76292.1 - 0.0012 19.4 5.7 0.086 13.4 7.5 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 AJZ76292.1 - 0.02 15.7 1.3 6.1 7.8 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AJZ76292.1 - 0.065 14.2 14.3 1.7 9.7 5.8 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 AJZ76292.1 - 0.37 11.6 12.8 55 4.6 2.5 2.5 1 1 1 2 2 2 0 4Fe-4S single cluster domain DNA_pol3_delta2 PF13177.6 AJZ76293.1 - 5.8e-16 58.7 0.4 1.7e-12 47.5 0.4 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 AJZ76293.1 - 1.8e-13 51.1 0.4 4.7e-13 49.7 0.1 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 AJZ76293.1 - 1.1e-09 38.6 0.3 1.1e-09 38.6 0.3 2.1 3 0 0 3 3 2 1 Replication factor C C-terminal domain AAA_16 PF13191.6 AJZ76293.1 - 2.8e-06 27.8 0.5 2.6e-05 24.7 0.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 AJZ76293.1 - 5.5e-06 26.3 0.4 1.3e-05 25.0 0.4 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 AJZ76293.1 - 6.3e-05 23.0 0.2 0.00019 21.4 0.1 2.0 2 1 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 AJZ76293.1 - 0.00011 22.0 0.0 0.00044 20.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF87 PF01935.17 AJZ76293.1 - 0.00024 21.3 3.0 0.21 11.7 1.9 2.3 2 1 0 2 2 2 2 Helicase HerA, central domain PhoH PF02562.16 AJZ76293.1 - 0.0003 20.3 0.7 0.46 9.9 0.4 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_14 PF13173.6 AJZ76293.1 - 0.0006 19.9 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 AJZ76293.1 - 0.00095 19.5 0.2 0.0023 18.3 0.2 1.7 1 0 0 1 1 1 1 AAA C-terminal domain IstB_IS21 PF01695.17 AJZ76293.1 - 0.0022 17.7 0.1 0.0065 16.2 0.1 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 AJZ76293.1 - 0.0026 17.8 0.3 0.019 15.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AJZ76293.1 - 0.0037 16.7 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AJZ76293.1 - 0.0042 17.4 1.9 0.51 10.6 0.1 2.5 1 1 1 2 2 2 1 AAA domain DEAD PF00270.29 AJZ76293.1 - 0.0086 15.9 0.2 0.34 10.7 0.1 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_3 PF07726.11 AJZ76293.1 - 0.0088 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AJZ76293.1 - 0.01 15.8 0.2 1.2 9.1 0.2 2.4 1 1 1 2 2 2 0 NACHT domain PTPlike_phytase PF14566.6 AJZ76293.1 - 0.014 15.5 0.3 0.047 13.8 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate T2SSE PF00437.20 AJZ76293.1 - 0.032 13.3 0.2 0.35 9.9 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 AJZ76293.1 - 0.032 13.8 0.2 0.064 12.8 0.2 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AJZ76293.1 - 0.041 13.8 0.2 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 AJZ76293.1 - 0.045 14.1 0.2 0.11 12.9 0.1 2.0 2 1 0 2 2 1 0 RNA helicase ResIII PF04851.15 AJZ76293.1 - 0.049 13.6 0.2 0.65 10.0 0.1 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 AJZ76293.1 - 0.066 13.3 0.0 0.28 11.2 0.0 1.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 AJZ76293.1 - 0.1 12.3 3.7 3.9 7.1 0.1 2.8 2 2 0 2 2 2 0 AAA domain Sld5 PF05916.11 AJZ76294.1 - 7.4e-06 26.4 1.6 1e-05 26.0 1.6 1.2 1 0 0 1 1 1 1 GINS complex protein MCM PF00493.23 AJZ76295.1 - 1.7e-93 311.9 0.0 2.5e-93 311.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 AJZ76295.1 - 9e-36 122.5 0.1 1.5e-35 121.8 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 AJZ76295.1 - 3e-22 78.8 0.2 6e-22 77.9 0.2 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 AJZ76295.1 - 3.5e-08 34.0 1.1 9.8e-08 32.5 1.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 AJZ76295.1 - 6.4e-07 29.4 0.0 1.2e-05 25.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AJZ76295.1 - 3.2e-06 26.7 0.0 0.00022 20.7 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AJZ76295.1 - 0.00081 19.3 0.0 0.0027 17.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AJZ76295.1 - 0.066 12.9 0.7 0.19 11.4 0.7 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 AJZ76295.1 - 0.12 12.0 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.29 AJZ76296.1 - 1.2e-26 93.6 0.1 2.7e-26 92.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AJZ76296.1 - 2.5e-13 50.4 0.0 4.6e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 AJZ76296.1 - 5.3e-12 46.2 0.5 1.9e-11 44.4 0.5 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain Helicase_C PF00271.31 AJZ76296.1 - 1.6e-11 44.6 0.1 4.2e-10 39.9 0.0 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DNA_pol_lambd_f PF10391.9 AJZ76296.1 - 1.9e-07 30.8 0.0 5.7e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_2 PF12826.7 AJZ76296.1 - 8.6e-07 29.0 0.1 4.1e-05 23.6 0.0 3.4 3 0 0 3 3 3 1 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 AJZ76296.1 - 0.0032 17.2 0.8 0.38 10.5 0.0 3.6 3 0 0 3 3 3 1 Bacterial RNA polymerase, alpha chain C terminal domain AAA_25 PF13481.6 AJZ76296.1 - 0.023 14.3 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AJZ76296.1 - 0.035 13.2 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IMS_HHH PF11798.8 AJZ76296.1 - 0.035 14.4 0.0 0.47 10.9 0.0 2.8 2 0 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 AJZ76296.1 - 0.085 13.2 0.1 0.43 11.0 0.1 2.3 1 1 0 1 1 1 0 Helix-hairpin-helix domain DnaB_C PF03796.15 AJZ76296.1 - 0.097 12.0 0.1 0.26 10.6 0.1 1.7 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain HHH PF00633.23 AJZ76296.1 - 0.13 12.2 0.0 0.91 9.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Glycos_transf_4 PF00953.21 AJZ76297.1 - 8.3e-30 103.9 14.5 8.3e-30 103.9 14.5 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 Hexapep PF00132.24 AJZ76298.1 - 6.3e-25 85.9 20.1 5.3e-10 38.6 0.3 3.9 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AJZ76298.1 - 1.9e-17 62.7 7.2 3.7e-08 33.0 2.9 4.4 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 AJZ76298.1 - 0.027 13.4 0.1 2.5 7.0 0.0 2.0 2 0 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 AJZ76298.1 - 0.32 9.1 1.9 0.52 8.4 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Trm112p PF03966.16 AJZ76299.1 - 2e-08 34.6 0.1 4.7e-08 33.5 0.1 1.6 1 1 0 1 1 1 1 Trm112p-like protein GFO_IDH_MocA PF01408.22 AJZ76300.1 - 3.3e-28 98.9 0.0 6e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AJZ76300.1 - 1e-06 28.7 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain IlvN PF07991.12 AJZ76300.1 - 0.00056 19.5 0.1 0.0012 18.5 0.1 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 AJZ76300.1 - 0.0016 17.8 0.1 0.0031 16.9 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 AJZ76300.1 - 0.0017 18.4 0.0 0.035 14.2 0.0 2.3 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 AJZ76300.1 - 0.005 17.0 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 AJZ76300.1 - 0.021 14.1 0.7 0.061 12.6 0.7 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_3 PF03447.16 AJZ76300.1 - 0.081 13.6 0.4 0.22 12.2 0.0 1.8 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain adh_short PF00106.25 AJZ76300.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Aminotran_4 PF01063.19 AJZ76301.1 - 1.7e-46 158.9 0.0 2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV CBM_X2 PF03442.14 AJZ76301.1 - 0.099 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain X2 Ephrin PF00812.17 AJZ76301.1 - 0.16 11.9 0.3 0.28 11.2 0.3 1.4 1 0 0 1 1 1 0 Ephrin DpaA_N PF16924.5 AJZ76302.1 - 0.088 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain HEAT_2 PF13646.6 AJZ76303.1 - 3.8e-15 56.1 0.3 1.3e-10 41.5 0.2 2.4 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 AJZ76303.1 - 1.6e-09 37.2 0.0 0.089 13.1 0.0 4.4 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.6 AJZ76303.1 - 4.4e-06 27.1 0.1 0.16 12.5 0.0 3.4 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 AJZ76303.1 - 0.004 17.2 0.8 0.46 10.5 0.4 3.0 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 AJZ76303.1 - 0.015 15.9 1.1 7.3 7.6 0.1 3.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.23 AJZ76303.1 - 0.081 13.0 0.1 11 6.2 0.0 3.2 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat Alba PF01918.21 AJZ76304.1 - 1.1e-11 44.4 0.1 1.1e-11 44.4 0.1 1.6 2 0 0 2 2 2 1 Alba Waikav_capsid_1 PF12264.8 AJZ76304.1 - 0.062 12.8 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 Waikavirus capsid protein 1 PEP_mutase PF13714.6 AJZ76305.1 - 1.8e-54 184.8 0.0 2.1e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 AJZ76305.1 - 9.5e-17 60.7 0.1 1.4e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Glycolytic PF00274.19 AJZ76305.1 - 0.053 12.2 0.0 0.081 11.6 0.0 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I HisG_C PF08029.11 AJZ76305.1 - 0.073 13.2 0.0 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 HisG, C-terminal domain DUF881 PF05949.12 AJZ76305.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF881) Dynein_attach_N PF15867.5 AJZ76305.1 - 0.11 12.5 0.3 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Dynein attachment factor N-terminus PadR PF03551.14 AJZ76308.1 - 1.7e-11 43.9 0.0 4.2e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.6 AJZ76308.1 - 2.5e-05 24.2 0.1 7.7e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix RTP PF02334.16 AJZ76308.1 - 0.00017 22.2 0.5 0.0044 17.7 0.0 2.4 1 1 0 2 2 2 1 Replication terminator protein Mrr_N PF14338.6 AJZ76308.1 - 0.0022 18.1 0.8 0.0079 16.3 0.1 2.2 3 0 0 3 3 3 1 Mrr N-terminal domain Hemocyanin_M PF00372.19 AJZ76308.1 - 0.0037 16.5 1.1 0.0047 16.2 1.1 1.1 1 0 0 1 1 1 1 Hemocyanin, copper containing domain DUF4364 PF14277.6 AJZ76308.1 - 0.0073 16.1 1.0 0.036 13.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4364) DUF1451 PF07295.11 AJZ76308.1 - 0.018 15.1 3.3 0.28 11.2 0.8 2.1 1 1 1 2 2 2 0 Zinc-ribbon containing domain FAD_binding_2 PF00890.24 AJZ76309.1 - 7.2e-102 341.6 0.1 8.8e-102 341.3 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AJZ76309.1 - 2.8e-34 117.8 0.6 4.4e-34 117.2 0.6 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AJZ76309.1 - 7.4e-08 32.0 0.1 2.4e-05 23.7 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AJZ76309.1 - 0.0002 20.9 0.1 0.16 11.3 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 AJZ76309.1 - 0.00067 18.5 0.2 0.49 9.0 0.3 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 AJZ76309.1 - 0.00091 18.5 1.7 0.006 15.8 0.2 2.7 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 AJZ76309.1 - 0.0017 17.5 0.2 0.059 12.4 0.3 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 AJZ76309.1 - 0.02 14.0 0.2 0.034 13.2 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 AJZ76309.1 - 0.025 14.2 0.1 0.089 12.4 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AJZ76309.1 - 0.083 12.1 0.3 1.2 8.4 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AJZ76309.1 - 0.17 12.2 0.8 0.93 9.8 0.4 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Sdh_cyt PF01127.22 AJZ76310.1 - 8.5e-10 38.7 2.7 1.2e-09 38.2 2.7 1.4 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sdh_cyt PF01127.22 AJZ76311.1 - 1.4e-07 31.6 1.8 1.7e-07 31.3 1.8 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 AJZ76311.1 - 0.025 14.7 1.6 0.037 14.1 1.6 1.3 1 0 0 1 1 1 0 Fumarate reductase subunit D FeS_assembly_P PF01883.19 AJZ76312.1 - 1.6e-16 60.3 0.0 2.2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein LPMO_10 PF03067.15 AJZ76313.1 - 0.024 15.3 0.1 0.095 13.4 0.0 1.6 1 1 1 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading AAA_23 PF13476.6 AJZ76313.1 - 0.26 11.7 12.4 0.35 11.3 12.4 1.2 1 0 0 1 1 1 0 AAA domain Inositol_P PF00459.25 AJZ76314.1 - 1.4e-28 100.2 0.0 1.6e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AJZ76314.1 - 0.00034 20.1 0.1 0.00057 19.4 0.1 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain CPSase_L_D2 PF02786.17 AJZ76316.1 - 1.7e-71 240.1 0.0 2.5e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AJZ76316.1 - 3.3e-46 156.3 0.0 6.2e-46 155.5 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AJZ76316.1 - 3.2e-34 117.3 0.0 6.3e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.22 AJZ76316.1 - 9.1e-11 41.6 0.1 1.7e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AJZ76316.1 - 3.4e-08 33.3 0.1 7.6e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 AJZ76316.1 - 2.1e-06 27.5 0.0 1.1e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 AJZ76316.1 - 1.8e-05 24.8 0.0 3.8e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AJZ76316.1 - 0.0001 21.9 0.0 0.00099 18.7 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 AJZ76316.1 - 0.028 14.2 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 AJZ76316.1 - 0.082 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 AJZ76316.1 - 0.12 11.6 0.0 0.38 10.0 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 AJZ76316.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF3182 PF11379.8 AJZ76316.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Biotin_lipoyl PF00364.22 AJZ76317.1 - 1e-16 60.5 6.3 1.4e-16 60.1 5.4 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AJZ76317.1 - 2.6e-11 43.2 4.5 5.8e-08 32.4 0.4 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 AJZ76317.1 - 4.5e-05 24.1 0.8 0.12 13.1 0.1 2.8 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AJZ76317.1 - 5.8e-05 22.4 1.0 0.043 13.0 0.1 2.6 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF2118 PF09891.9 AJZ76317.1 - 0.00065 19.7 0.4 0.0018 18.2 0.3 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 AJZ76317.1 - 0.004 17.0 1.3 0.0083 16.0 0.8 1.9 2 0 0 2 2 2 1 Glycine cleavage H-protein PCC_BT PF18140.1 AJZ76317.1 - 0.012 15.9 0.4 0.043 14.2 0.1 1.9 1 1 1 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain RnfC_N PF13375.6 AJZ76317.1 - 0.031 14.2 3.8 0.067 13.1 3.2 1.9 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain QRPTase_N PF02749.16 AJZ76317.1 - 0.058 13.4 0.1 0.27 11.3 0.0 2.1 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Peptidase_M23 PF01551.22 AJZ76317.1 - 0.073 13.3 2.8 2.9 8.1 0.1 3.2 2 1 1 3 3 3 0 Peptidase family M23 PASTA PF03793.19 AJZ76317.1 - 0.13 12.2 2.6 0.18 11.7 0.7 2.1 1 1 1 2 2 2 0 PASTA domain AhpC-TSA PF00578.21 AJZ76318.1 - 2.4e-33 114.7 0.0 2.7e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJZ76318.1 - 9.4e-23 80.6 0.0 1e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 AJZ76318.1 - 0.0048 16.8 0.1 0.0073 16.2 0.1 1.4 1 1 0 1 1 1 1 SCO1/SenC PRD_Mga PF08270.11 AJZ76318.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain AhpC-TSA_2 PF13911.6 AJZ76318.1 - 0.16 12.1 0.0 3.5 7.8 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme Oxidored_q4 PF00507.19 AJZ76319.1 - 3.3e-17 62.5 0.6 4.2e-17 62.1 0.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Gram_pos_anchor PF00746.21 AJZ76319.1 - 1.5 8.8 4.9 0.58 10.2 0.4 2.3 2 1 0 2 2 2 0 LPXTG cell wall anchor motif DUF2244 PF10003.9 AJZ76319.1 - 3.1 7.5 8.3 3.8 7.2 0.5 2.2 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) Oxidored_q6 PF01058.22 AJZ76320.1 - 1.9e-24 86.0 0.1 2.5e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_30kDa PF00329.19 AJZ76321.1 - 1.2e-35 122.8 0.1 1.5e-35 122.5 0.1 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit AMP-binding_C_2 PF14535.6 AJZ76321.1 - 0.11 12.8 0.3 0.18 12.1 0.3 1.3 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Cys_Met_Meta_PP PF01053.20 AJZ76321.1 - 0.17 10.4 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Complex1_49kDa PF00346.19 AJZ76322.1 - 3.4e-73 246.1 0.0 8.5e-57 192.3 0.0 2.1 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NADHdh PF00146.21 AJZ76323.1 - 6.9e-96 321.1 20.0 9.6e-96 320.6 20.0 1.1 1 0 0 1 1 1 1 NADH dehydrogenase Fer4 PF00037.27 AJZ76324.1 - 3.1e-12 45.8 11.4 3.3e-09 36.2 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJZ76324.1 - 8.3e-09 35.9 7.9 1.4e-08 35.2 7.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJZ76324.1 - 5e-08 33.0 20.7 3.6e-06 27.0 10.5 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJZ76324.1 - 5.7e-08 32.8 17.5 0.00014 21.9 0.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AJZ76324.1 - 1e-06 29.1 1.5 0.0047 17.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJZ76324.1 - 1.4e-06 28.4 8.5 5e-06 26.6 9.2 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AJZ76324.1 - 9.1e-06 25.5 9.9 0.0014 18.6 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AJZ76324.1 - 1.3e-05 25.0 12.4 4.4e-05 23.4 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AJZ76324.1 - 2.7e-05 24.3 8.4 0.012 16.0 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AJZ76324.1 - 0.0004 21.3 9.6 0.0039 18.1 0.2 2.3 1 1 2 3 3 3 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AJZ76324.1 - 0.001 19.6 9.8 0.028 14.9 0.7 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_15 PF13459.6 AJZ76324.1 - 0.0026 18.4 6.7 0.23 12.2 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.7 AJZ76324.1 - 0.011 16.6 4.1 0.011 16.6 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 AJZ76324.1 - 0.028 15.0 7.9 0.15 12.6 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 AJZ76324.1 - 0.1 13.4 0.4 0.1 13.4 0.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AJZ76324.1 - 0.11 12.7 9.1 0.21 11.8 0.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Oxidored_q3 PF00499.20 AJZ76325.1 - 2.6e-22 79.1 14.7 3.8e-22 78.6 14.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4131 PF13567.6 AJZ76325.1 - 0.25 11.0 0.1 0.25 11.0 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Oxidored_q2 PF00420.24 AJZ76326.1 - 1.7e-23 82.2 7.3 2.3e-23 81.8 7.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Proton_antipo_C PF01010.19 AJZ76326.1 - 0.38 10.3 2.6 0.44 10.1 2.6 1.0 1 0 0 1 1 1 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus YiaAB PF05360.14 AJZ76326.1 - 4.6 7.6 7.6 5.4 7.3 0.4 2.3 2 0 0 2 2 2 0 yiaA/B two helix domain DUF202 PF02656.15 AJZ76326.1 - 4.7 7.7 7.5 20 5.7 7.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Proton_antipo_M PF00361.20 AJZ76327.1 - 2.6e-64 217.3 22.0 2.6e-64 217.3 22.0 2.6 2 1 1 3 3 3 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AJZ76327.1 - 0.00025 21.0 0.2 0.00025 21.0 0.2 2.9 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus MadM PF03818.13 AJZ76327.1 - 0.37 10.7 8.2 0.62 10.0 4.1 3.4 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit Proton_antipo_M PF00361.20 AJZ76328.1 - 5.6e-69 232.6 25.3 5.6e-69 232.6 25.3 2.3 2 0 0 2 2 2 1 Proton-conducting membrane transporter polyprenyl_synt PF00348.17 AJZ76329.1 - 1.3e-48 165.4 0.0 1.7e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase TENA_THI-4 PF03070.16 AJZ76330.1 - 4.3e-11 43.0 1.1 5.8e-11 42.6 1.1 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.6 AJZ76330.1 - 1.2e-10 41.5 0.1 1.5e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 Iron-containing redox enzyme Phage_holin_6_1 PF09682.10 AJZ76330.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) HisKA PF00512.25 AJZ76331.1 - 2.7e-07 30.5 0.0 4.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4208 PF13907.6 AJZ76331.1 - 0.024 15.1 0.0 0.032 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) MEDS PF14417.6 AJZ76332.1 - 1.4e-14 54.2 0.0 1.8e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain ATPase PF06745.13 AJZ76332.1 - 4.7e-05 22.9 0.1 6e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 KaiC KdgM PF06178.13 AJZ76332.1 - 0.029 14.0 0.1 0.053 13.1 0.1 1.4 1 0 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) DUF5085 PF16895.5 AJZ76332.1 - 0.085 13.2 1.4 1.5 9.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5085) Ago_PAZ PF18309.1 AJZ76332.1 - 0.12 13.0 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 Argonaute PAZ domain Usp PF00582.26 AJZ76333.1 - 1e-23 84.4 0.0 1.1e-23 84.3 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Peptidase_M15_4 PF13539.6 AJZ76333.1 - 0.15 12.6 0.1 0.24 11.9 0.1 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase TBP PF00352.21 AJZ76334.1 - 3.4e-52 174.3 0.0 2.1e-25 88.5 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 AJZ76334.1 - 3.8e-08 33.3 0.0 0.00071 19.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Sigma70_r1_1 PF03979.14 AJZ76334.1 - 0.079 13.0 0.0 8.1 6.6 0.0 2.8 2 1 1 3 3 3 0 Sigma-70 factor, region 1.1 Pribosyltran PF00156.27 AJZ76335.1 - 1.9e-14 53.5 0.2 2.7e-14 53.0 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 AJZ76335.1 - 0.00057 19.4 0.1 0.0011 18.5 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosyl transferase UPRTase PF14681.6 AJZ76335.1 - 0.0085 15.6 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase P5CR_dimer PF14748.6 AJZ76335.1 - 0.094 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Peptidase_M50 PF02163.22 AJZ76336.1 - 3.2e-11 43.0 13.4 2e-07 30.6 13.4 3.1 1 1 0 1 1 1 1 Peptidase family M50 Acetyltransf_1 PF00583.25 AJZ76337.1 - 3.1e-21 75.8 0.1 4e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AJZ76337.1 - 4.2e-14 52.7 1.1 4.8e-14 52.5 0.2 1.4 2 0 0 2 2 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AJZ76337.1 - 5.8e-13 48.9 0.1 9.7e-13 48.2 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AJZ76337.1 - 5.4e-10 39.1 0.0 2.5e-09 37.0 0.0 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 AJZ76337.1 - 3.5e-06 27.2 0.1 4.7e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AJZ76337.1 - 7.1e-05 22.5 0.1 8.1e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_8 PF13523.6 AJZ76337.1 - 0.00026 20.7 0.0 0.00076 19.2 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AJZ76337.1 - 0.0017 18.4 0.0 0.0039 17.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AJZ76337.1 - 0.0024 18.6 0.0 0.0029 18.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4821 PF16092.5 AJZ76337.1 - 0.028 14.0 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) Acetyltransf_15 PF17013.5 AJZ76337.1 - 0.03 13.8 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 AJZ76337.1 - 0.03 14.5 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Gly_acyl_tr_C PF08444.10 AJZ76337.1 - 0.075 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region ABC_tran PF00005.27 AJZ76339.1 - 1.3e-38 132.7 0.3 1.1e-17 64.8 0.0 3.0 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 AJZ76339.1 - 1.1e-10 41.2 2.8 1.1e-10 41.2 2.8 1.8 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 AJZ76339.1 - 5.7e-09 35.4 11.5 1.5e-08 34.1 5.8 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 AJZ76339.1 - 2.9e-08 33.4 13.5 3.9e-07 29.9 4.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain SMC_N PF02463.19 AJZ76339.1 - 2.2e-07 30.6 5.6 0.0012 18.3 0.6 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Fer4_2 PF12797.7 AJZ76339.1 - 9.2e-07 28.6 1.8 9.2e-07 28.6 1.8 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_21 PF13304.6 AJZ76339.1 - 2.6e-06 27.5 2.6 2 8.2 0.3 4.3 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Fer4_10 PF13237.6 AJZ76339.1 - 3.6e-05 23.8 12.6 6.3e-05 23.0 1.4 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJZ76339.1 - 5e-05 23.3 13.3 8.6e-05 22.6 13.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AJZ76339.1 - 7.1e-05 23.3 10.0 0.00015 22.3 10.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain RsgA_GTPase PF03193.16 AJZ76339.1 - 0.00092 19.2 0.1 0.15 12.0 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 AJZ76339.1 - 0.0011 18.7 0.2 0.67 9.7 0.0 3.5 4 0 0 4 4 4 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AJZ76339.1 - 0.011 16.2 0.3 2.8 8.3 0.1 3.3 2 1 1 3 3 3 0 AAA ATPase domain Fer4_16 PF13484.6 AJZ76339.1 - 0.016 16.1 1.9 0.016 16.1 1.9 2.6 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AJZ76339.1 - 0.022 14.9 10.3 0.06 13.5 10.5 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain MMR_HSR1 PF01926.23 AJZ76339.1 - 0.025 14.7 0.1 4 7.5 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase NB-ARC PF00931.22 AJZ76339.1 - 0.035 13.3 1.6 6.3 5.9 0.3 3.0 3 1 0 3 3 3 0 NB-ARC domain Fer4_4 PF12800.7 AJZ76339.1 - 0.041 14.4 2.3 0.041 14.4 2.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Rad17 PF03215.15 AJZ76339.1 - 0.042 13.8 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 AJZ76339.1 - 0.056 13.8 0.1 11 6.5 0.0 3.7 4 0 0 4 4 4 0 RNA helicase AAA_15 PF13175.6 AJZ76339.1 - 0.084 12.6 2.8 5.8 6.5 0.4 2.7 2 2 0 2 2 2 0 AAA ATPase domain DLIC PF05783.11 AJZ76339.1 - 0.13 11.0 0.4 0.97 8.2 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Fer4_3 PF12798.7 AJZ76339.1 - 0.21 12.6 16.0 0.11 13.5 5.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain MeaB PF03308.16 AJZ76339.1 - 0.23 10.4 0.7 0.79 8.6 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 AJZ76339.1 - 0.38 11.2 2.9 27 5.2 0.0 3.2 2 1 0 3 3 3 0 AAA domain AAA_14 PF13173.6 AJZ76339.1 - 0.55 10.3 2.3 6.9 6.7 0.0 3.6 4 2 2 6 6 4 0 AAA domain Fer4_17 PF13534.6 AJZ76339.1 - 2.1 9.0 9.2 0.21 12.2 1.3 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AJZ76339.1 - 4.7 8.0 10.0 0.64 10.8 3.9 2.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain Fer4_8 PF13183.6 AJZ76339.1 - 6.6 7.3 8.7 0.59 10.6 1.4 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Peptidase_M17 PF00883.21 AJZ76340.1 - 2.8e-118 394.8 0.0 3.5e-118 394.4 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 AJZ76340.1 - 1.1e-16 60.8 0.2 2.6e-16 59.7 0.2 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DUF393 PF04134.12 AJZ76341.1 - 0.023 16.0 0.0 0.033 15.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF393 TAL_FSA PF00923.19 AJZ76342.1 - 1.5e-61 208.3 0.1 2.3e-60 204.4 0.1 2.2 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase FMN_dh PF01070.18 AJZ76342.1 - 0.098 11.7 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase TBP PF00352.21 AJZ76344.1 - 7.4e-53 176.5 0.0 2e-26 91.7 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 AJZ76344.1 - 1e-06 28.8 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) PAS_11 PF14598.6 AJZ76344.1 - 0.057 13.5 0.0 5.7 7.1 0.0 2.1 1 1 1 2 2 2 0 PAS domain ASCH PF04266.14 AJZ76345.1 - 3.6e-10 40.4 0.0 4.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 ASCH domain VWA PF00092.28 AJZ76346.1 - 2.3e-09 37.7 0.2 6.5e-09 36.3 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 AJZ76346.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 AJZ76346.1 - 0.00033 21.3 0.1 0.0014 19.3 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 AJZ76346.1 - 0.0071 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 AJZ76346.1 - 0.0083 16.2 0.9 0.52 10.4 0.1 2.6 2 1 0 2 2 2 1 vWA found in TerF C terminus DUF2201 PF09967.9 AJZ76346.1 - 0.011 15.8 0.4 0.063 13.4 0.0 2.3 3 0 0 3 3 3 0 VWA-like domain (DUF2201) Copine PF07002.16 AJZ76346.1 - 0.051 13.0 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 Copine AAA_5 PF07728.14 AJZ76347.1 - 7.8e-23 81.0 0.0 1.1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 AJZ76347.1 - 9.6e-12 44.9 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 AJZ76347.1 - 1.4e-06 28.8 0.0 2.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AJZ76347.1 - 1.9e-05 25.1 0.4 4.5e-05 23.9 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 AJZ76347.1 - 0.00017 21.7 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AJZ76347.1 - 0.00051 20.0 0.0 0.00099 19.1 0.0 1.5 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 AJZ76347.1 - 0.00051 19.6 0.0 0.00087 18.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 AJZ76347.1 - 0.00059 20.1 0.1 0.0011 19.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 AJZ76347.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 AJZ76347.1 - 0.0055 17.3 0.0 0.0093 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 AJZ76347.1 - 0.0066 16.7 0.1 0.025 14.8 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 AJZ76347.1 - 0.0075 16.5 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_6 PF12774.7 AJZ76347.1 - 0.01 14.9 0.0 0.071 12.1 0.0 1.9 1 1 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Mg_chelatase PF01078.21 AJZ76347.1 - 0.012 15.0 0.0 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AJZ76347.1 - 0.026 14.2 0.2 0.38 10.5 0.2 2.2 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 AJZ76347.1 - 0.03 14.1 0.1 0.064 13.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 AJZ76347.1 - 0.033 13.6 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_11 PF13086.6 AJZ76347.1 - 0.034 13.9 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 AJZ76347.1 - 0.047 13.8 0.0 0.093 12.9 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 AJZ76347.1 - 0.049 13.8 0.1 0.096 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain CbbQ_C PF08406.10 AJZ76347.1 - 0.051 13.8 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal TsaE PF02367.17 AJZ76347.1 - 0.057 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_35 PF14516.6 AJZ76347.1 - 0.074 11.9 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 AJZ76347.1 - 0.083 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 AJZ76347.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 AJZ76347.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 AJZ76347.1 - 0.17 11.6 0.1 0.43 10.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AJZ76347.1 - 0.17 12.4 0.1 0.39 11.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter RNA_binding PF01877.17 AJZ76348.1 - 3.2e-27 95.2 0.5 3.8e-27 94.9 0.5 1.1 1 0 0 1 1 1 1 RNA binding P16-Arc PF04699.14 AJZ76348.1 - 0.027 14.9 0.0 0.037 14.5 0.0 1.2 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Ribosomal_S3Ae PF01015.18 AJZ76349.1 - 5.7e-57 192.6 4.5 6.5e-57 192.4 4.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family OrfB_IS605 PF01385.19 AJZ76349.1 - 0.0068 16.6 0.5 0.011 15.9 0.5 1.3 1 0 0 1 1 1 1 Probable transposase tRNA-synt_2b PF00587.25 AJZ76350.1 - 3.7e-37 128.0 0.2 7.6e-37 127.0 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AJZ76350.1 - 1.1e-24 86.7 9.6 2.5e-24 85.6 9.6 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain HIP1_clath_bdg PF16515.5 AJZ76350.1 - 0.029 15.0 3.9 4.2 8.1 0.0 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FmiP_Thoc5 PF09766.9 AJZ76350.1 - 0.041 13.2 6.3 0.049 12.9 3.8 2.0 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 APG6_N PF17675.1 AJZ76350.1 - 0.16 12.5 9.2 0.28 11.7 4.4 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Dynactin_p22 PF07426.11 AJZ76350.1 - 3.4 7.5 8.6 0.87 9.4 5.3 1.6 2 0 0 2 2 2 0 Dynactin subunit p22 Pcc1 PF09341.10 AJZ76351.1 - 3.2e-07 30.4 0.1 3.6e-07 30.2 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DHHA1 PF02272.19 AJZ76352.1 - 7e-12 45.9 0.2 2.2e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 DHHA1 domain DHH PF01368.20 AJZ76352.1 - 0.0048 17.1 0.1 0.009 16.2 0.1 1.5 1 0 0 1 1 1 1 DHH family Ribosomal_S13_N PF08069.12 AJZ76353.1 - 1.2e-24 86.1 0.5 2.1e-24 85.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 AJZ76353.1 - 1.2e-10 41.4 1.8 1.8e-10 40.9 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Mucin15 PF15672.5 AJZ76353.1 - 0.1 12.0 0.2 0.24 10.8 0.3 1.6 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 DUF348 PF03990.14 AJZ76353.1 - 0.16 11.7 0.3 6 6.7 0.0 2.6 2 1 0 2 2 2 0 G5-linked-Ubiquitin-like domain Phage_lysozyme2 PF18013.1 AJZ76354.1 - 0.11 12.5 0.4 0.14 12.2 0.4 1.3 1 1 0 1 1 1 0 Phage tail lysozyme DUF4179 PF13786.6 AJZ76354.1 - 0.24 11.9 0.1 0.24 11.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) FixQ PF05545.11 AJZ76355.1 - 0.037 14.0 2.8 0.037 14.0 2.8 1.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF5493 PF17597.2 AJZ76355.1 - 0.06 13.6 2.4 0.077 13.3 2.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5493) Monooxygenase_B PF04744.12 AJZ76357.1 - 3.3e-10 39.3 0.1 2.5e-09 36.5 0.1 2.0 1 1 0 1 1 1 1 Monooxygenase subunit B protein AmoC PF04896.12 AJZ76358.1 - 3.8e-13 49.3 6.2 4.8e-13 49.0 6.2 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C RTA1 PF04479.13 AJZ76358.1 - 0.0045 16.6 0.4 0.0065 16.1 0.4 1.2 1 0 0 1 1 1 1 RTA1 like protein ETRAMP PF09716.10 AJZ76359.1 - 0.79 9.8 0.1 0.79 9.8 0.1 2.2 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Archaeal_AmoA PF12942.7 AJZ76360.1 - 2.5e-117 389.1 15.9 3e-117 388.9 15.9 1.1 1 0 0 1 1 1 1 Archaeal ammonia monooxygenase subunit A (AmoA) MethyltransfD12 PF02086.15 AJZ76361.1 - 9.5e-62 209.0 0.3 1.1e-61 208.8 0.3 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase DUF2089 PF09862.9 AJZ76361.1 - 0.0028 17.7 0.1 0.0059 16.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) DNA_photolyase PF00875.18 AJZ76361.1 - 0.048 13.7 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 DNA photolyase Cons_hypoth95 PF03602.15 AJZ76361.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 LOH1CR12 PF10158.9 AJZ76362.1 - 0.024 14.6 0.2 0.2 11.7 0.2 2.0 1 1 1 2 2 2 0 Tumour suppressor protein Lectin_like PF18560.1 AJZ76362.1 - 0.055 13.6 0.1 0.07 13.3 0.1 1.1 1 0 0 1 1 1 0 Lectin like domain TSP_NTD PF17804.1 AJZ76362.1 - 0.095 13.0 0.4 0.12 12.6 0.4 1.1 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Sulf_transp PF04143.14 AJZ76363.1 - 0.011 15.3 2.7 0.067 12.8 2.8 1.8 1 1 0 1 1 1 0 Sulphur transport Gram_pos_anchor PF00746.21 AJZ76363.1 - 0.012 15.6 10.2 0.042 13.8 0.2 4.1 4 0 0 4 4 4 0 LPXTG cell wall anchor motif Phage_holin_3_6 PF07332.11 AJZ76363.1 - 0.02 14.9 0.1 4.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2627 PF11118.8 AJZ76363.1 - 0.046 14.3 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) Cytadhesin_P30 PF07271.11 AJZ76363.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 HTH_24 PF13412.6 AJZ76364.1 - 0.00014 21.3 0.1 0.00026 20.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AJZ76364.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.12 AJZ76364.1 - 0.0002 21.2 0.3 0.0005 20.0 0.0 1.8 2 0 0 2 2 2 1 HTH domain FaeA PF04703.12 AJZ76364.1 - 0.0014 19.0 0.1 0.0044 17.4 0.0 1.8 2 0 0 2 2 2 1 FaeA-like protein HTH_29 PF13551.6 AJZ76364.1 - 0.0021 18.0 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Crp_2 PF13545.6 AJZ76364.1 - 0.0052 16.7 0.2 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 AJZ76364.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 AJZ76364.1 - 0.037 14.2 0.1 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix of insertion element transposase MarR_2 PF12802.7 AJZ76364.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 MarR family HrcA_DNA-bdg PF03444.15 AJZ76364.1 - 0.18 11.5 0.7 0.48 10.1 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding AhpC-TSA PF00578.21 AJZ76365.1 - 7.3e-21 74.4 0.2 9.1e-21 74.1 0.2 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJZ76365.1 - 1.2e-18 67.2 0.2 1.6e-18 66.9 0.2 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 AJZ76365.1 - 0.00019 21.7 0.1 0.0003 21.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AJZ76365.1 - 0.0012 19.2 0.1 0.0019 18.6 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 AJZ76365.1 - 0.019 15.0 0.4 0.33 10.9 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.6 AJZ76365.1 - 0.096 12.5 0.1 0.32 10.8 0.1 1.8 1 1 0 1 1 1 0 F plasmid transfer operon protein CARDB PF07705.11 AJZ76366.1 - 0.0012 19.1 0.3 0.019 15.2 0.0 2.8 2 1 1 3 3 3 1 CARDB DUF2393 PF09624.10 AJZ76366.1 - 0.04 13.9 0.2 5.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) DUF1702 PF08012.11 AJZ76366.1 - 0.087 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) NPCBM_assoc PF10633.9 AJZ76366.1 - 0.097 12.9 0.1 2.9 8.2 0.1 2.7 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Wzt_C PF14524.6 AJZ76366.1 - 0.1 12.6 0.0 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 Wzt C-terminal domain CTP_transf_like PF01467.26 AJZ76367.1 - 1.4e-14 54.5 0.0 1.7e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like DpaA_N PF16924.5 AJZ76367.1 - 0.019 15.0 0.1 0.13 12.3 0.0 2.0 1 1 1 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain CdiA_C_tRNase PF18664.1 AJZ76367.1 - 0.08 13.1 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain Sial-lect-inser PF09264.10 AJZ76369.1 - 0.043 13.6 0.4 0.049 13.4 0.4 1.1 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion tRNA-synt_1b PF00579.25 AJZ76370.1 - 3.8e-28 98.7 0.0 6.3e-28 97.9 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 AJZ76370.1 - 0.031 13.2 0.0 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA_synthFbeta PF17759.1 AJZ76371.1 - 4.5e-41 140.6 0.0 8.8e-41 139.7 0.0 1.5 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 AJZ76371.1 - 2.9e-14 53.1 0.0 1.4e-08 34.9 0.0 3.7 3 0 0 3 3 3 2 tRNA synthetase B5 domain B3_4 PF03483.17 AJZ76371.1 - 5e-13 49.1 0.1 8.8e-13 48.3 0.1 1.3 1 0 0 1 1 1 1 B3/4 domain EVE PF01878.18 AJZ76372.1 - 4e-41 140.4 1.1 4.6e-41 140.2 1.1 1.0 1 0 0 1 1 1 1 EVE domain ATG11 PF10377.9 AJZ76372.1 - 0.012 15.6 0.1 0.016 15.3 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 11 DUF4932 PF16286.5 AJZ76373.1 - 0.011 15.0 1.9 0.017 14.4 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4932) Zn_ribbon_17 PF17120.5 AJZ76374.1 - 0.0055 16.3 1.8 0.0088 15.6 1.8 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type C1_2 PF03107.16 AJZ76374.1 - 0.05 13.9 2.8 0.05 13.9 2.8 1.6 1 1 1 2 2 2 0 C1 domain Jas PF16135.5 AJZ76374.1 - 0.087 13.0 2.5 0.13 12.4 2.5 1.4 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling C1_1 PF00130.22 AJZ76374.1 - 0.21 11.5 6.5 0.32 10.9 6.5 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Mu-like_Com PF10122.9 AJZ76374.1 - 2 7.9 7.7 13 5.4 7.7 2.1 1 1 0 1 1 1 0 Mu-like prophage protein Com Cas_Cmr5 PF09701.10 AJZ76375.1 - 0.064 13.6 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) Aconitase PF00330.20 AJZ76376.1 - 5.3e-146 487.2 0.0 7.5e-146 486.7 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 AJZ76376.1 - 1.2e-37 129.1 0.0 2.6e-37 128.1 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 AJZ76376.1 - 0.066 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Holin_BlyA PF05102.12 AJZ76377.1 - 0.067 13.1 0.1 0.067 13.1 0.1 3.8 4 0 0 4 4 4 0 holin, BlyA family SOR_SNZ PF01680.17 AJZ76378.1 - 1.2e-97 325.7 3.9 1.2e-97 325.7 3.9 1.7 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 AJZ76378.1 - 3.5e-07 29.8 1.7 8e-06 25.3 0.1 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 AJZ76378.1 - 1.4e-06 27.9 5.1 0.00087 18.8 0.3 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 AJZ76378.1 - 1.3e-05 24.8 0.6 0.0057 16.2 0.1 3.1 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 AJZ76378.1 - 0.0023 17.1 0.0 0.032 13.4 0.0 2.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase Dus PF01207.17 AJZ76378.1 - 0.0024 17.0 0.2 1.4 8.0 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 AJZ76378.1 - 0.0054 15.9 2.2 0.15 11.3 0.0 2.8 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Phos_pyr_kin PF08543.12 AJZ76378.1 - 0.013 14.9 0.8 0.021 14.2 0.8 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase OMPdecase PF00215.24 AJZ76378.1 - 0.026 14.1 0.6 3.8 7.0 0.0 2.5 2 1 1 3 3 3 0 Orotidine 5'-phosphate decarboxylase / HUMPS family SNO PF01174.19 AJZ76379.1 - 9e-50 169.1 0.0 1e-49 169.0 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase PF00117.28 AJZ76379.1 - 3.5e-12 46.5 0.0 6.6e-12 45.6 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 AJZ76379.1 - 5.3e-12 45.7 0.1 7.1e-12 45.3 0.1 1.3 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 AJZ76379.1 - 3.9e-06 26.8 0.4 7.4e-06 25.9 0.2 1.5 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 AJZ76379.1 - 1.7e-05 24.6 0.1 2.6e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family S51 Peptidase_C26 PF07722.13 AJZ76379.1 - 0.00031 20.6 0.5 0.061 13.1 0.3 3.0 2 1 0 2 2 2 1 Peptidase C26 Entericidin PF08085.11 AJZ76379.1 - 0.058 13.4 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 Entericidin EcnA/B family tRNA-synt_1 PF00133.22 AJZ76380.1 - 2.8e-108 362.7 0.1 4.7e-107 358.7 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AJZ76380.1 - 4.8e-30 104.5 1.4 1.1e-29 103.3 1.4 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AJZ76380.1 - 1.3e-21 76.8 1.8 5.7e-13 48.4 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AJZ76380.1 - 0.00041 19.9 0.2 0.041 13.4 0.0 2.8 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Pterin_4a PF01329.19 AJZ76381.1 - 9.4e-34 115.5 0.4 1.1e-33 115.2 0.4 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.8 AJZ76381.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.5 2 0 0 2 2 2 0 Translation-initiation factor 2 Asn_synthase PF00733.21 AJZ76382.1 - 1.1e-26 94.3 0.0 4.3e-20 72.7 0.0 2.0 1 1 1 2 2 2 2 Asparagine synthase NAD_synthase PF02540.17 AJZ76382.1 - 9.2e-07 28.2 0.1 1.6e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 AJZ76382.1 - 0.00017 21.1 0.1 0.00039 20.0 0.1 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 AJZ76382.1 - 0.00023 20.1 0.1 0.0026 16.6 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.20 AJZ76382.1 - 0.002 17.9 0.4 0.01 15.6 0.4 2.2 1 1 0 1 1 1 1 PP-loop family Diphthami_syn_2 PF01902.17 AJZ76382.1 - 0.0064 16.0 0.1 0.051 13.1 0.0 2.1 2 0 0 2 2 2 1 Diphthamide synthase UDPG_MGDP_dh PF00984.19 AJZ76382.1 - 0.15 12.2 1.1 15 5.8 0.1 3.6 4 0 0 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Lyase_1 PF00206.20 AJZ76383.1 - 8.2e-46 156.8 0.5 1.2e-45 156.2 0.5 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 AJZ76383.1 - 2.1e-14 53.8 0.0 4.5e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 AJZ76383.1 - 0.0039 17.3 0.0 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal RtcB PF01139.17 AJZ76384.1 - 4.6e-167 556.4 0.0 5.2e-167 556.2 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Complex1_LYR PF05347.15 AJZ76384.1 - 0.0083 16.2 0.4 0.084 12.9 0.1 2.3 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF3492 PF11997.8 AJZ76384.1 - 0.016 14.9 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) dsDNA_bind PF01984.20 AJZ76385.1 - 3.7e-10 40.1 0.8 4.7e-10 39.7 0.8 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Orthopox_F8 PF05886.11 AJZ76385.1 - 0.0069 16.5 0.1 0.01 16.0 0.1 1.3 1 0 0 1 1 1 1 Orthopoxvirus F8 protein EF-1_beta_acid PF10587.9 AJZ76385.1 - 0.011 16.1 3.1 0.011 16.1 3.1 1.9 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Ribosomal_S11 PF00411.19 AJZ76387.1 - 1.6e-41 141.1 2.4 1.9e-41 140.9 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 AJZ76387.1 - 0.02 15.1 0.5 0.034 14.4 0.1 1.6 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) PaRep2b PF07775.11 AJZ76387.1 - 0.058 11.9 0.0 0.081 11.4 0.0 1.3 1 1 0 1 1 1 0 PaRep2b protein Tagatose_6_P_K PF08013.11 AJZ76387.1 - 0.13 10.9 0.3 0.2 10.3 0.3 1.4 1 1 0 1 1 1 0 Tagatose 6 phosphate kinase Nif11 PF07862.11 AJZ76387.1 - 1.7 9.0 3.5 2.2 8.7 0.0 2.5 3 0 0 3 3 3 0 Nif11 domain AIRS PF00586.24 AJZ76388.1 - 3.1e-12 47.0 0.0 5.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PGM_PMM_I PF02878.16 AJZ76389.1 - 1.2e-24 86.6 0.0 6.1e-24 84.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AJZ76389.1 - 8.4e-17 61.4 0.1 2.2e-16 60.0 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AJZ76389.1 - 4.2e-12 46.6 0.1 1.2e-11 45.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AJZ76389.1 - 1.8e-06 28.0 0.0 7.4e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain NLE PF08154.12 AJZ76389.1 - 0.0062 17.0 0.1 0.016 15.7 0.1 1.7 1 0 0 1 1 1 1 NLE (NUC135) domain NAD_binding_8 PF13450.6 AJZ76389.1 - 0.086 13.1 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain B12-binding PF02310.19 AJZ76389.1 - 0.095 12.7 0.0 0.91 9.6 0.0 2.4 1 1 0 1 1 1 0 B12 binding domain HTH_45 PF14947.6 AJZ76390.1 - 6e-15 55.0 0.2 6.8e-15 54.8 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.6 AJZ76390.1 - 0.00045 20.0 0.1 0.00053 19.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_34 PF13601.6 AJZ76390.1 - 0.0031 17.7 0.1 0.0039 17.3 0.1 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF505 PF04458.12 AJZ76390.1 - 0.038 12.3 0.1 0.039 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Rrf2 PF02082.20 AJZ76390.1 - 0.042 14.2 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator Mrr_N PF14338.6 AJZ76390.1 - 0.063 13.4 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 Mrr N-terminal domain LcrR PF09621.10 AJZ76390.1 - 0.087 12.3 0.0 0.099 12.1 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) dCache_3 PF14827.6 AJZ76390.1 - 0.092 12.4 0.0 0.098 12.3 0.0 1.0 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase TrmB PF01978.19 AJZ76390.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 AJZ76390.1 - 0.14 12.8 0.1 0.18 12.4 0.1 1.2 1 0 0 1 1 1 0 Replication protein A C terminal AIPR PF10592.9 AJZ76392.1 - 5.3e-60 203.5 6.1 5.3e-60 203.5 6.1 1.8 2 0 0 2 2 2 1 AIPR protein RGS PF00615.19 AJZ76392.1 - 0.044 14.1 0.2 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 Regulator of G protein signaling domain L_protein_N PF15518.6 AJZ76392.1 - 0.069 13.0 1.1 6 6.8 0.1 2.6 2 0 0 2 2 2 0 L protein N-terminus Cupredoxin_1 PF13473.6 AJZ76393.1 - 9.8e-08 32.1 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 AJZ76393.1 - 1.1e-05 25.8 0.1 3.2e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family CBFD_NFYB_HMF PF00808.23 AJZ76394.1 - 8.4e-13 48.4 0.1 1e-12 48.2 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 AJZ76394.1 - 0.00014 22.2 0.1 0.00017 21.9 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 AJZ76394.1 - 0.00016 22.1 0.2 0.00018 21.8 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 AJZ76394.1 - 0.00032 20.8 0.1 0.00037 20.6 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 AJZ76394.1 - 0.0011 18.9 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 AJZ76394.1 - 0.0036 17.3 0.0 0.004 17.2 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Ribosomal_S17e PF00833.18 AJZ76395.1 - 4e-15 55.8 3.7 4.5e-15 55.7 3.7 1.1 1 0 0 1 1 1 1 Ribosomal S17 Lipocalin_9 PF17186.4 AJZ76395.1 - 0.059 13.6 0.1 0.07 13.4 0.1 1.1 1 0 0 1 1 1 0 Lipocalin-like domain ThiS PF02597.20 AJZ76396.1 - 1.2e-10 41.9 0.0 2e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 ThiS family CGI-121 PF08617.10 AJZ76396.1 - 2.3e-06 27.8 0.9 3.7e-06 27.2 0.9 1.4 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Urm1 PF09138.11 AJZ76396.1 - 0.0094 16.3 0.2 0.029 14.7 0.2 1.9 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) TrkA_C PF02080.21 AJZ76396.1 - 0.11 12.3 0.1 4.6 7.2 0.0 2.5 2 0 0 2 2 2 0 TrkA-C domain THUMP PF02926.17 AJZ76397.1 - 1.4e-10 41.5 0.1 1.8e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 THUMP domain CdiA_C PF18451.1 AJZ76397.1 - 0.61 10.3 4.1 0.57 10.4 2.1 1.9 2 1 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain HTH_45 PF14947.6 AJZ76398.1 - 1.9e-11 43.8 0.1 2.5e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.7 AJZ76398.1 - 6.6e-05 22.7 0.0 8.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 MarR family DUF4364 PF14277.6 AJZ76398.1 - 0.0022 17.7 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_27 PF13463.6 AJZ76398.1 - 0.0027 18.1 0.0 0.0036 17.8 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AJZ76398.1 - 0.0087 15.8 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 AJZ76398.1 - 0.013 15.3 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 AJZ76398.1 - 0.022 14.7 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF1495 PF07381.11 AJZ76398.1 - 0.022 14.5 0.0 0.035 13.9 0.0 1.4 1 1 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) Rrf2 PF02082.20 AJZ76398.1 - 0.033 14.5 0.0 0.041 14.2 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator RPA_C PF08784.11 AJZ76398.1 - 0.035 14.8 0.1 0.047 14.4 0.1 1.2 1 0 0 1 1 1 0 Replication protein A C terminal FtsK_gamma PF09397.10 AJZ76398.1 - 0.036 13.9 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Ftsk gamma domain RQC PF09382.10 AJZ76398.1 - 0.045 13.5 0.0 0.054 13.3 0.0 1.3 1 1 0 1 1 1 0 RQC domain MarR PF01047.22 AJZ76398.1 - 0.056 13.4 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 MarR family Mrr_N PF14338.6 AJZ76398.1 - 0.066 13.4 0.0 0.12 12.6 0.0 1.4 1 1 0 1 1 1 0 Mrr N-terminal domain DUF4806 PF16064.5 AJZ76398.1 - 0.069 13.4 0.0 0.095 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) Dimerisation2 PF16864.5 AJZ76398.1 - 0.074 13.0 0.0 0.095 12.7 0.0 1.1 1 0 0 1 1 1 0 Dimerisation domain HTH_24 PF13412.6 AJZ76398.1 - 0.09 12.4 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cdc6_C PF09079.11 AJZ76398.1 - 0.095 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4194 PF13835.6 AJZ76398.1 - 0.17 11.6 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) MerC PF03203.14 AJZ76399.1 - 0.26 11.7 11.8 0.83 10.1 2.4 2.4 1 1 1 2 2 2 0 MerC mercury resistance protein CitMHS PF03600.16 AJZ76399.1 - 4.3 6.4 11.9 13 4.9 11.9 1.8 1 1 0 1 1 1 0 Citrate transporter zf-TFIIB PF13453.6 AJZ76400.1 - 0.0071 15.7 0.9 0.031 13.6 1.4 1.8 2 0 0 2 2 2 1 Transcription factor zinc-finger Ribosomal_S27e PF01667.17 AJZ76400.1 - 0.021 14.5 2.6 2.9 7.7 0.4 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 IBR PF01485.21 AJZ76400.1 - 0.033 14.4 0.4 0.036 14.3 0.4 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Lar_restr_allev PF14354.6 AJZ76400.1 - 0.041 14.3 1.3 0.076 13.4 1.3 1.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar Stc1 PF12898.7 AJZ76400.1 - 0.066 13.8 0.2 0.079 13.5 0.2 1.1 1 0 0 1 1 1 0 Stc1 domain zinc_ribbon_4 PF13717.6 AJZ76400.1 - 0.16 11.9 4.8 1.6 8.7 4.8 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-ACC PF17848.1 AJZ76400.1 - 5.6 7.1 8.0 17 5.6 3.5 2.4 2 1 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Iron_traffic PF04362.14 AJZ76401.1 - 1.6e-06 27.7 0.1 2.8e-06 26.9 0.0 1.4 2 0 0 2 2 2 1 Bacterial Fe(2+) trafficking Peptidase_M26_N PF05342.14 AJZ76403.1 - 0.079 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region OMPdecase PF00215.24 AJZ76404.1 - 3.4e-25 89.0 0.0 4.4e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family NUDIX PF00293.28 AJZ76405.1 - 1.6e-19 70.3 0.0 2e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain DUF3592 PF12158.8 AJZ76405.1 - 0.14 12.2 0.2 0.63 10.1 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) Prenyltransf PF01255.19 AJZ76406.1 - 1.9e-70 236.9 0.1 2.2e-70 236.7 0.1 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase SpoVR PF04293.13 AJZ76406.1 - 0.035 12.8 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 SpoVR like protein PIN_12 PF16289.5 AJZ76406.1 - 0.04 14.4 0.3 0.078 13.5 0.3 1.6 1 1 0 1 1 1 0 PIN domain DUF2089 PF09862.9 AJZ76406.1 - 0.11 12.5 0.3 0.28 11.2 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2089) DUF373 PF04123.13 AJZ76407.1 - 4.6e-89 299.2 7.0 5.4e-89 298.9 7.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF373) Fst_toxin PF13955.6 AJZ76407.1 - 0.65 10.0 3.6 0.64 10.0 0.3 2.7 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system DUF4229 PF14012.6 AJZ76407.1 - 1 9.5 7.2 20 5.4 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) DIX PF00778.17 AJZ76408.1 - 0.088 12.6 0.2 0.62 9.9 0.0 2.2 2 0 0 2 2 2 0 DIX domain DUF424 PF04242.13 AJZ76409.1 - 2e-19 69.6 0.4 2.4e-19 69.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF424) eIF-1a PF01176.19 AJZ76410.1 - 3.5e-19 68.4 0.6 4.5e-19 68.0 0.6 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myosin_N PF02736.19 AJZ76410.1 - 0.0058 16.4 1.3 0.082 12.8 0.1 2.2 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain MCM6_C PF18263.1 AJZ76410.1 - 0.15 12.3 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain KH_1 PF00013.29 AJZ76411.1 - 5.9e-10 38.8 9.9 1.9e-06 27.6 0.9 2.5 2 0 0 2 2 2 2 KH domain DUF4921 PF16268.5 AJZ76411.1 - 0.065 12.0 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) HIN PF02760.15 AJZ76411.1 - 0.11 12.2 0.2 0.2 11.4 0.1 1.5 2 0 0 2 2 2 0 HIN-200/IF120x domain KH_2 PF07650.17 AJZ76411.1 - 3.2 7.7 6.8 9 6.2 1.2 2.7 2 1 0 2 2 2 0 KH domain Topo-VIb_trans PF09239.11 AJZ76412.1 - 1.2e-56 191.0 0.0 2e-56 190.2 0.0 1.4 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c PF02518.26 AJZ76412.1 - 1.9e-06 28.4 0.0 3.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AJZ76412.1 - 3.3e-05 23.7 0.0 6.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FbpA PF05833.11 AJZ76412.1 - 0.15 10.8 2.6 0.16 10.7 0.0 2.1 3 0 0 3 3 3 0 Fibronectin-binding protein A N-terminus (FbpA) TP6A_N PF04406.14 AJZ76413.1 - 3.6e-15 55.7 0.0 6.3e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Toprim PF01751.22 AJZ76413.1 - 0.015 15.6 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 Toprim domain DUF4870 PF09685.10 AJZ76414.1 - 0.037 14.1 2.4 0.056 13.6 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) GvpH PF05455.11 AJZ76414.1 - 0.048 13.7 0.0 0.055 13.6 0.0 1.1 1 0 0 1 1 1 0 GvpH DUF4181 PF13789.6 AJZ76414.1 - 0.048 13.9 2.5 0.066 13.5 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) DUF2207 PF09972.9 AJZ76414.1 - 0.075 11.8 1.1 0.088 11.6 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3043 PF11241.8 AJZ76414.1 - 0.11 12.5 0.3 0.15 12.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF2061 PF09834.9 AJZ76415.1 - 0.013 16.0 1.9 0.018 15.6 1.9 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2061) TrmB PF01978.19 AJZ76416.1 - 0.0034 17.2 0.0 0.0057 16.5 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PNP_UDP_1 PF01048.20 AJZ76417.1 - 1.5e-48 165.1 0.0 1.8e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Pribosyltran PF00156.27 AJZ76418.1 - 9.1e-15 54.5 0.1 1e-14 54.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AJZ76418.1 - 0.00041 19.9 0.0 0.00057 19.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AJZ76418.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase MG2 PF01835.19 AJZ76419.1 - 2e-26 92.3 1.1 0.0001 22.6 0.0 6.2 5 1 0 6 6 6 4 MG2 domain FlgD_ig PF13860.6 AJZ76419.1 - 3.6e-06 26.7 12.0 0.0023 17.8 0.0 5.9 5 1 2 7 7 7 2 FlgD Ig-like domain Gmad2 PF10648.9 AJZ76419.1 - 0.008 16.4 0.2 21 5.5 0.1 4.4 4 0 0 4 4 4 1 Immunoglobulin-like domain of bacterial spore germination HdeA PF06411.11 AJZ76419.1 - 0.011 16.0 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 HdeA/HdeB family Big_6 PF17936.1 AJZ76419.1 - 0.31 11.3 11.7 0.28 11.5 0.1 5.5 4 2 1 6 6 6 0 Bacterial Ig domain AAA_15 PF13175.6 AJZ76420.1 - 3.4e-23 83.0 3.3 3.4e-23 83.0 3.3 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 AJZ76420.1 - 7.5e-13 49.0 8.2 3.4e-11 43.5 1.8 3.5 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 AJZ76420.1 - 1.4e-05 25.6 0.2 8.9e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter DUF2813 PF11398.8 AJZ76420.1 - 0.0035 16.6 0.5 0.9 8.7 0.0 3.0 4 0 0 4 4 4 2 Protein of unknown function (DUF2813) AAA_27 PF13514.6 AJZ76420.1 - 0.0039 16.8 0.2 0.027 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AJZ76420.1 - 0.011 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Kinesin_assoc PF16183.5 AJZ76420.1 - 0.037 14.2 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 Kinesin-associated SMC_N PF02463.19 AJZ76420.1 - 0.067 12.6 0.0 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AJZ76420.1 - 0.092 13.2 12.5 0.012 16.2 5.7 2.8 2 1 0 2 2 2 0 AAA domain FtsJ PF01728.19 AJZ76422.1 - 1e-48 165.8 0.0 1.1e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 AJZ76422.1 - 0.00072 20.2 0.2 0.0099 16.6 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJZ76422.1 - 0.0009 19.1 0.1 0.0015 18.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJZ76422.1 - 0.0025 17.7 0.0 0.0053 16.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TRM PF02005.16 AJZ76423.1 - 2.8e-74 250.6 0.0 3.4e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 AJZ76423.1 - 0.0009 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 AJZ76423.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RNase_HII PF01351.18 AJZ76424.1 - 1.7e-48 165.1 1.8 2e-48 164.9 1.8 1.0 1 0 0 1 1 1 1 Ribonuclease HII Cas9_PI PF16595.5 AJZ76424.1 - 0.008 16.1 0.4 0.011 15.7 0.4 1.1 1 0 0 1 1 1 1 PAM-interacting domain of CRISPR-associated endonuclease Cas9 Colicin PF01024.19 AJZ76424.1 - 0.088 12.7 3.2 0.15 11.9 0.5 2.0 1 1 1 2 2 2 0 Colicin pore forming domain Fibrillarin PF01269.17 AJZ76425.1 - 6.6e-87 290.4 0.1 7.9e-87 290.1 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin PCMT PF01135.19 AJZ76425.1 - 9e-05 22.3 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 AJZ76425.1 - 0.0035 17.1 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DUF4651 PF15513.6 AJZ76425.1 - 0.043 13.6 0.2 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Methyltransf_23 PF13489.6 AJZ76425.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DHO_dh PF01180.21 AJZ76426.1 - 7.4e-52 176.4 0.5 8.3e-52 176.2 0.5 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.17 AJZ76426.1 - 7.4e-08 31.8 0.1 0.00013 21.2 0.0 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AJZ76426.1 - 4.6e-05 23.0 0.3 0.0067 15.9 0.1 2.2 2 0 0 2 2 2 2 Histidine biosynthesis protein G3P_antiterm PF04309.12 AJZ76426.1 - 0.00014 21.4 0.5 0.56 9.6 0.1 2.5 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator DUF561 PF04481.12 AJZ76426.1 - 0.00034 19.8 2.8 0.00094 18.4 0.2 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF561) NMO PF03060.15 AJZ76426.1 - 0.00067 19.1 2.5 0.015 14.7 0.1 2.0 1 1 0 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.25 AJZ76426.1 - 0.0014 17.7 2.8 0.0016 17.5 0.2 2.0 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.20 AJZ76426.1 - 0.049 12.5 0.6 5.4 5.8 0.1 2.2 2 0 0 2 2 2 0 Tryptophan synthase alpha chain ThiG PF05690.14 AJZ76426.1 - 0.056 12.7 3.6 2.1 7.6 0.1 2.9 1 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 AJZ76426.1 - 0.085 11.9 0.1 1.5 7.7 0.0 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase TMP-TENI PF02581.17 AJZ76426.1 - 0.17 11.2 0.9 1.3 8.4 0.2 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase NAD_binding_1 PF00175.21 AJZ76427.1 - 3.3e-08 34.1 0.0 6.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.9 AJZ76427.1 - 8.5e-08 31.9 7.0 3.4e-07 30.0 7.5 1.8 2 0 0 2 2 2 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.24 AJZ76427.1 - 0.0022 18.3 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain SH3_17 PF18350.1 AJZ76427.1 - 0.093 12.6 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Restriction endonuclease SH3 domain NAD_binding_7 PF13241.6 AJZ76427.1 - 0.096 13.1 0.0 0.22 12.0 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Radical_SAM PF04055.21 AJZ76428.1 - 1.5e-10 41.7 0.0 4.4e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_S30 PF04758.14 AJZ76429.1 - 1.8e-09 37.7 5.1 2.6e-09 37.1 5.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S30 Conotoxin PF02950.17 AJZ76430.1 - 0.067 14.2 0.1 0.08 14.0 0.1 1.1 1 0 0 1 1 1 0 Conotoxin CRCB PF02537.15 AJZ76431.1 - 9.9e-20 70.7 9.7 1.3e-19 70.3 9.7 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) DUF2104 PF09877.9 AJZ76431.1 - 0.014 15.7 2.7 0.015 15.6 1.6 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2104) MRG PF05712.13 AJZ76432.1 - 0.0031 16.8 0.3 0.0043 16.4 0.3 1.3 1 0 0 1 1 1 1 MRG Rad51 PF08423.11 AJZ76435.1 - 1.3e-88 296.6 0.0 1.8e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 AJZ76435.1 - 2.4e-11 43.6 0.0 3.3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 AJZ76435.1 - 1.1e-08 35.5 0.4 4.5e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 AJZ76435.1 - 7.9e-08 31.9 0.1 1.9e-07 30.7 0.1 1.7 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 AJZ76435.1 - 1.6e-05 24.5 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AJZ76435.1 - 0.031 14.0 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AJZ76435.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DNA_pol_lambd_f PF10391.9 AJZ76435.1 - 0.14 12.1 0.0 0.44 10.4 0.0 1.9 1 1 0 1 1 1 0 Fingers domain of DNA polymerase lambda LBP_M PF17385.2 AJZ76435.1 - 0.15 11.6 0.1 0.39 10.2 0.0 1.6 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase central domain XOO_2897-deam PF14440.6 AJZ76435.1 - 0.16 12.1 0.1 12 6.0 0.0 2.8 2 1 1 3 3 3 0 Xanthomonas XOO_2897-like deaminase Ribosomal_L21e PF01157.18 AJZ76436.1 - 1.7e-19 69.5 1.3 2.4e-19 69.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_pol_Rpb4 PF03874.16 AJZ76437.1 - 1.2e-09 38.6 2.5 2.5e-09 37.5 2.5 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 Integrase_Zn PF02022.19 AJZ76437.1 - 0.041 13.9 0.0 0.45 10.5 0.0 2.2 2 0 0 2 2 2 0 Integrase Zinc binding domain Mrr_N PF14338.6 AJZ76437.1 - 0.15 12.2 1.0 12 6.2 0.1 2.1 1 1 1 2 2 2 0 Mrr N-terminal domain DUF655 PF04919.12 AJZ76438.1 - 8.8e-52 175.7 0.4 1e-51 175.5 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.6 AJZ76438.1 - 5.9e-06 26.5 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.7 AJZ76438.1 - 0.00086 19.5 0.2 0.0041 17.3 0.0 2.2 2 1 1 3 3 3 1 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 AJZ76438.1 - 0.086 13.2 0.5 2.3 8.6 0.0 2.2 1 1 1 2 2 2 0 Ribosomal protein S13/S18 RrnaAD PF00398.20 AJZ76439.1 - 2.7e-43 148.0 0.3 3.1e-43 147.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 AJZ76439.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 AJZ76439.1 - 0.029 15.1 0.0 0.065 14.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 AJZ76439.1 - 0.072 12.9 0.0 0.1 12.4 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 AJZ76440.1 - 4.7e-09 36.0 0.0 1.6e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 AJZ76440.1 - 2.1e-07 30.9 0.0 1.5e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJZ76440.1 - 1.1e-06 28.5 0.0 1.5e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJZ76440.1 - 0.00057 20.5 0.0 0.0024 18.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AJZ76440.1 - 0.0019 18.0 0.0 0.0043 16.8 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 AJZ76440.1 - 0.0024 18.6 0.0 0.017 15.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AJZ76440.1 - 0.0035 16.5 0.0 0.0088 15.1 0.0 1.5 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.12 AJZ76440.1 - 0.0043 16.2 0.0 0.0058 15.8 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_12 PF08242.12 AJZ76440.1 - 0.0089 16.7 0.1 0.25 12.1 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 AJZ76440.1 - 0.051 13.3 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 AJZ76440.1 - 0.093 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 AJZ76440.1 - 0.098 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Iso_dh PF00180.20 AJZ76441.1 - 4.6e-78 262.8 0.0 5.7e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Metallophos PF00149.28 AJZ76442.1 - 3.5e-17 63.6 0.1 4.8e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AJZ76442.1 - 6e-15 55.8 0.0 8.7e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 AJZ76442.1 - 1.5e-05 24.5 0.3 8.6e-05 22.0 0.1 2.0 1 1 1 2 2 2 1 Metallophosphoesterase, calcineurin superfamily PhoD PF09423.10 AJZ76442.1 - 0.099 11.6 0.0 10 5.0 0.0 2.4 2 1 0 2 2 2 0 PhoD-like phosphatase DoxX PF07681.12 AJZ76443.1 - 2.9e-14 53.4 6.3 2.9e-14 53.4 6.3 1.7 2 0 0 2 2 2 1 DoxX DoxX_2 PF13564.6 AJZ76443.1 - 3.9e-06 26.9 6.7 4.9e-06 26.6 6.7 1.2 1 0 0 1 1 1 1 DoxX-like family DoxD PF04173.13 AJZ76443.1 - 3.3e-05 23.9 3.1 3.3e-05 23.9 3.1 1.5 1 1 1 2 2 2 1 TQO small subunit DoxD DUF2892 PF11127.8 AJZ76443.1 - 4.1 7.5 8.3 13 5.9 3.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2892) CCD48 PF15799.5 AJZ76444.1 - 0.00022 19.7 0.0 0.00022 19.7 0.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 Dynamitin PF04912.14 AJZ76444.1 - 0.0051 16.2 0.1 0.0056 16.1 0.1 1.0 1 0 0 1 1 1 1 Dynamitin NUDE_C PF04880.13 AJZ76444.1 - 0.014 15.9 0.3 0.015 15.8 0.3 1.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region WD40_alt PF14077.6 AJZ76444.1 - 0.031 14.1 1.5 0.28 11.1 1.5 2.1 1 1 0 1 1 1 0 Alternative WD40 repeat motif Prefoldin_2 PF01920.20 AJZ76444.1 - 0.033 14.2 0.2 0.04 13.9 0.2 1.1 1 0 0 1 1 1 0 Prefoldin subunit DUF1192 PF06698.11 AJZ76444.1 - 0.05 13.6 1.0 0.081 13.0 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) bZIP_1 PF00170.21 AJZ76444.1 - 0.054 13.6 0.8 0.075 13.1 0.8 1.4 1 1 0 1 1 1 0 bZIP transcription factor TPD52 PF04201.15 AJZ76444.1 - 0.056 13.1 0.1 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 Tumour protein D52 family DivIC PF04977.15 AJZ76444.1 - 0.17 11.7 1.5 0.33 10.7 1.5 1.5 1 1 1 2 2 2 0 Septum formation initiator Transglut_core2 PF13369.6 AJZ76445.1 - 2.5e-43 147.3 0.0 3.7e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 AJZ76445.1 - 7.3e-20 70.9 0.4 1.1e-19 70.3 0.4 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 AJZ76445.1 - 1.6e-05 24.7 1.2 0.00084 19.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 AJZ76445.1 - 2.7e-05 23.8 2.5 0.001 18.8 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJZ76445.1 - 9.5e-05 22.4 1.7 0.14 12.3 0.0 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 AJZ76445.1 - 0.00018 22.0 0.4 0.064 14.1 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 AJZ76445.1 - 0.00075 19.7 0.3 0.0023 18.2 0.3 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 AJZ76445.1 - 0.13 12.9 0.1 0.31 11.7 0.1 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 AJZ76445.1 - 0.15 12.3 0.9 0.64 10.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RhoGEF PF00621.20 AJZ76446.1 - 0.0017 18.6 0.8 0.0062 16.8 0.0 2.1 3 0 0 3 3 3 1 RhoGEF domain HHH_4 PF14490.6 AJZ76446.1 - 0.11 12.5 1.1 0.9 9.6 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix containing domain NADPH_Ox PF08414.10 AJZ76446.1 - 0.13 12.6 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase Ald_Xan_dh_C PF01315.22 AJZ76446.1 - 0.14 12.6 0.1 0.56 10.6 0.0 2.0 2 1 0 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Methyltransf_25 PF13649.6 AJZ76448.1 - 3.3e-07 30.9 0.0 5.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJZ76448.1 - 1.1e-06 29.2 0.0 1.7e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Trm112p PF03966.16 AJZ76448.1 - 4.7e-05 23.9 0.6 0.0018 18.8 0.4 2.7 2 0 0 2 2 2 1 Trm112p-like protein Methyltransf_23 PF13489.6 AJZ76448.1 - 5.1e-05 23.2 0.0 0.0001 22.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJZ76448.1 - 0.0011 19.6 0.0 0.0025 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AJZ76448.1 - 0.023 14.3 0.0 0.044 13.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain NodS PF05401.11 AJZ76448.1 - 0.075 12.6 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 Nodulation protein S (NodS) YccV-like PF08755.11 AJZ76448.1 - 0.088 13.3 0.0 0.17 12.4 0.0 1.5 1 1 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like Topoisom_I PF01028.20 AJZ76450.1 - 4.6e-69 232.2 5.6 7.9e-69 231.4 5.6 1.3 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 AJZ76450.1 - 1.2e-64 217.7 5.4 1.2e-64 217.7 5.4 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 AJZ76450.1 - 1.2e-19 69.9 7.7 1.5e-19 69.7 2.8 2.8 2 0 0 2 2 2 1 C-terminal topoisomerase domain W2 PF02020.18 AJZ76450.1 - 0.003 17.6 2.4 0.03 14.5 0.0 2.9 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon adh_short PF00106.25 AJZ76451.1 - 1.3e-51 174.8 0.0 1.7e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AJZ76451.1 - 7.7e-38 130.4 0.0 1e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJZ76451.1 - 9.9e-12 45.1 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AJZ76451.1 - 5.9e-07 29.1 0.0 3.8e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 AJZ76451.1 - 0.00075 19.1 0.0 0.0017 17.9 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 AJZ76451.1 - 0.041 13.8 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding Epimerase PF01370.21 AJZ76451.1 - 0.058 12.8 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Filamin PF00630.19 AJZ76452.1 - 0.025 15.4 4.9 0.045 14.6 4.9 1.6 1 1 0 1 1 1 0 Filamin/ABP280 repeat AIF_C PF14721.6 AJZ76452.1 - 0.032 14.6 4.0 0.046 14.1 2.9 1.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ATP11 PF06644.11 AJZ76452.1 - 0.11 12.2 10.5 0.15 11.8 10.5 1.1 1 0 0 1 1 1 0 ATP11 protein CPSF100_C PF13299.6 AJZ76452.1 - 0.11 12.6 4.2 0.15 12.2 4.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MCM_bind PF09739.9 AJZ76452.1 - 0.74 8.2 8.1 0.9 7.9 8.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Presenilin PF01080.17 AJZ76452.1 - 0.94 8.2 4.3 1.2 7.8 4.3 1.2 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 AJZ76452.1 - 1.2 9.5 9.0 2.1 8.8 9.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 AJZ76452.1 - 7.2 5.7 9.8 1 8.5 6.3 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Connexin PF00029.19 AJZ76452.1 - 8.6 6.0 6.4 12 5.6 6.4 1.2 1 0 0 1 1 1 0 Connexin HTH_5 PF01022.20 AJZ76453.1 - 1.6e-15 56.7 0.1 7.4e-08 32.1 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AJZ76453.1 - 6.6e-15 54.4 0.3 1.5e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AJZ76453.1 - 3.1e-06 27.2 0.0 0.06 13.4 0.0 2.4 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_34 PF13601.6 AJZ76453.1 - 1e-05 25.6 0.1 0.017 15.3 0.0 2.2 2 0 0 2 2 2 2 Winged helix DNA-binding domain HTH_40 PF14493.6 AJZ76453.1 - 2.9e-05 24.4 1.9 0.1 13.1 0.5 2.2 1 1 1 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 AJZ76453.1 - 3.1e-05 23.8 0.0 0.075 12.9 0.0 2.5 2 1 0 2 2 2 2 MarR family MarR PF01047.22 AJZ76453.1 - 5.7e-05 23.0 0.6 0.11 12.4 0.2 2.6 2 1 0 2 2 2 2 MarR family HTH_IclR PF09339.10 AJZ76453.1 - 0.00024 20.8 0.0 0.34 10.7 0.0 2.3 2 0 0 2 2 2 2 IclR helix-turn-helix domain HxlR PF01638.17 AJZ76453.1 - 0.011 15.5 0.2 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 HxlR-like helix-turn-helix RepL PF05732.11 AJZ76453.1 - 0.015 14.7 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Sulfolobus_pRN PF05584.11 AJZ76453.1 - 0.017 15.2 0.3 0.063 13.3 0.1 2.0 2 1 0 2 2 2 0 Sulfolobus plasmid regulatory protein HTH_36 PF13730.6 AJZ76453.1 - 0.02 14.8 0.0 0.054 13.5 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 AJZ76453.1 - 0.042 13.7 0.0 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.16 AJZ76453.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3489 PF11994.8 AJZ76453.1 - 0.14 12.2 0.0 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) DUF4625 PF15418.6 AJZ76456.1 - 0.068 13.4 1.1 16 5.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4625) DUF3873 PF12989.7 AJZ76456.1 - 0.17 12.3 0.0 0.79 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) Gastrin PF00918.17 AJZ76457.1 - 0.028 15.4 2.0 0.029 15.3 2.0 1.0 1 0 0 1 1 1 0 Gastrin/cholecystokinin family ATP-synt_B PF00430.18 AJZ76457.1 - 0.036 14.2 6.2 0.05 13.7 6.2 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) IgaA PF07095.11 AJZ76457.1 - 0.064 11.2 0.3 0.07 11.1 0.3 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Ly49 PF08391.10 AJZ76457.1 - 0.12 12.7 0.8 0.16 12.4 0.8 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region RelE PF06296.12 AJZ76457.1 - 0.35 11.0 6.1 0.14 12.3 2.3 1.9 1 1 1 2 2 2 0 RelE toxin of RelE / RelB toxin-antitoxin system MFA1_2 PF17317.2 AJZ76457.1 - 5.4 6.9 5.9 2 8.3 0.4 2.3 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 DEAD PF00270.29 AJZ76458.1 - 4.9e-31 107.8 0.1 1.2e-30 106.6 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AJZ76458.1 - 1.9e-15 57.2 3.1 2.8e-11 43.7 0.3 3.9 4 0 0 4 4 4 2 Helicase conserved C-terminal domain DUF1998 PF09369.10 AJZ76458.1 - 1.8e-10 41.4 0.1 4.6e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Rad1 PF02144.16 AJZ76458.1 - 0.0025 16.9 0.2 0.0043 16.2 0.2 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF2325 PF10087.9 AJZ76458.1 - 0.0059 16.7 0.8 0.087 13.0 0.0 3.3 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2325) Lar_restr_allev PF14354.6 AJZ76458.1 - 0.16 12.3 0.1 0.16 12.3 0.1 1.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF5113 PF17140.4 AJZ76459.1 - 0.047 13.5 0.1 0.052 13.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) N6_N4_Mtase PF01555.18 AJZ76460.1 - 2.2e-36 125.7 5.0 2.6e-36 125.5 5.0 1.0 1 0 0 1 1 1 1 DNA methylase UPF0020 PF01170.18 AJZ76460.1 - 0.00098 18.9 0.0 0.24 11.0 0.0 2.5 2 1 0 2 2 2 2 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 AJZ76460.1 - 0.0015 17.9 0.1 0.13 11.5 0.1 2.1 2 0 0 2 2 2 2 N-6 DNA Methylase N6-adenineMlase PF10237.9 AJZ76460.1 - 0.0032 17.3 0.3 0.0076 16.1 0.2 1.7 2 1 0 2 2 2 1 Probable N6-adenine methyltransferase MTS PF05175.14 AJZ76460.1 - 0.027 14.0 0.0 0.3 10.6 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase small domain MttA_Hcf106 PF02416.16 AJZ76461.1 - 1.4e-07 30.7 0.0 2e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 mttA/Hcf106 family Lip_A_acyltrans PF03279.13 AJZ76461.1 - 0.00072 18.8 0.0 0.00094 18.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase DUF4389 PF14333.6 AJZ76461.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) DUF768 PF05589.11 AJZ76462.1 - 0.00011 22.2 0.1 2.2 8.3 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF768) CBM_14 PF01607.24 AJZ76462.1 - 0.037 14.2 0.4 0.087 13.0 0.0 1.8 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain MFS_1 PF07690.16 AJZ76463.1 - 2.6e-36 125.3 43.2 9.5e-26 90.5 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AJZ76463.1 - 8.2e-20 71.4 23.0 1e-19 71.1 23.0 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AJZ76463.1 - 1.4e-08 34.0 27.6 5.3e-06 25.5 17.3 2.0 1 1 1 2 2 2 2 MFS_1 like family OATP PF03137.20 AJZ76463.1 - 0.0013 17.1 16.9 0.0095 14.3 1.5 3.1 1 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MASE2 PF05230.11 AJZ76463.1 - 0.22 11.6 0.2 0.22 11.6 0.2 3.4 3 1 1 4 4 4 0 MASE2 domain Ubie_methyltran PF01209.18 AJZ76464.1 - 2.4e-17 63.1 0.0 3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 AJZ76464.1 - 8.5e-13 48.8 0.0 1.2e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJZ76464.1 - 8.4e-11 42.4 0.0 1.2e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJZ76464.1 - 2.1e-06 27.6 0.1 1.3e-05 25.1 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJZ76464.1 - 3e-06 27.2 0.0 3.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJZ76464.1 - 5.9e-05 23.7 0.0 0.00013 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 AJZ76464.1 - 0.0081 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 AJZ76464.1 - 0.029 13.6 0.0 0.055 12.8 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase NodS PF05401.11 AJZ76464.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF555 PF04475.12 AJZ76464.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF555) Putative_PNPOx PF01243.20 AJZ76465.1 - 2.2e-05 24.5 0.0 3.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F420H2_quin_red PF04075.14 AJZ76465.1 - 0.0075 16.4 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase Pyrid_ox_like PF16242.5 AJZ76465.1 - 0.17 11.5 0.0 0.23 11.0 0.0 1.3 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like ELFV_dehydrog PF00208.21 AJZ76466.1 - 8.9e-72 241.7 1.3 1.3e-71 241.2 1.3 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 AJZ76466.1 - 1.8e-47 160.4 0.0 3.9e-47 159.4 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 AJZ76466.1 - 0.00027 20.3 0.1 0.00055 19.4 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 AJZ76466.1 - 0.012 15.7 0.5 0.036 14.1 0.2 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 AJZ76466.1 - 0.017 14.4 0.1 0.029 13.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 AJZ76466.1 - 0.023 15.1 0.1 0.042 14.3 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding CoA_transf_3 PF02515.17 AJZ76466.1 - 0.081 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 CoA-transferase family III IlvN PF07991.12 AJZ76466.1 - 0.089 12.4 1.1 0.96 9.0 0.2 2.2 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ThiF PF00899.21 AJZ76466.1 - 0.13 11.6 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 ThiF family LEA_2 PF03168.13 AJZ76467.1 - 0.023 15.2 0.0 0.16 12.5 0.0 1.9 1 1 1 2 2 2 0 Late embryogenesis abundant protein DUF2897 PF11446.8 AJZ76467.1 - 0.8 9.6 2.6 1.5 8.7 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ECH_1 PF00378.20 AJZ76468.1 - 1.3e-65 221.2 1.3 1.5e-65 221.0 1.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AJZ76468.1 - 2.6e-37 129.1 0.5 1.1e-35 123.7 0.6 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF4975 PF16346.5 AJZ76468.1 - 0.084 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) Fe-S_biosyn PF01521.20 AJZ76469.1 - 8.7e-23 80.6 0.0 9.7e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Toprim_4 PF13662.6 AJZ76470.1 - 2.9e-07 30.9 0.2 8.3e-07 29.4 0.2 1.8 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AJZ76470.1 - 1.2e-05 25.6 0.0 2.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 AJZ76470.1 - 0.014 15.6 0.8 0.052 13.8 0.2 2.3 3 1 0 3 3 3 0 Toprim domain CTP-dep_RFKase PF01982.16 AJZ76471.1 - 4.6e-41 139.7 0.0 6.4e-41 139.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF120 MarR PF01047.22 AJZ76471.1 - 0.0035 17.2 0.1 0.019 14.9 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AJZ76471.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 AJZ76471.1 - 0.067 13.0 0.2 6.3 6.7 0.0 2.6 2 0 0 2 2 2 0 LexA DNA binding domain CTP_transf_like PF01467.26 AJZ76472.1 - 6.1e-11 42.7 0.0 8.4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like HTH_24 PF13412.6 AJZ76472.1 - 0.14 11.8 0.1 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TP_methylase PF00590.20 AJZ76473.1 - 2.4e-19 70.1 0.0 4e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF357 PF04010.13 AJZ76473.1 - 2.8e-14 53.0 0.1 2.4e-13 49.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF357) Ala_racemase_C PF00842.21 AJZ76473.1 - 0.052 13.4 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Alanine racemase, C-terminal domain Peptidase_M20 PF01546.28 AJZ76474.1 - 1.9e-28 99.6 0.0 3.4e-28 98.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AJZ76474.1 - 5.8e-15 55.2 0.2 1.2e-14 54.2 0.2 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 AJZ76474.1 - 3e-06 26.5 1.0 0.012 14.6 0.1 2.7 2 1 1 3 3 3 2 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 AJZ76474.1 - 1.1e-05 25.2 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Big_3 PF07523.12 AJZ76474.1 - 0.11 12.8 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) RimK PF08443.11 AJZ76475.1 - 3.6e-30 105.0 0.0 5.6e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 AJZ76475.1 - 2e-07 30.5 0.1 2.7e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 AJZ76475.1 - 1.1e-06 28.8 0.1 1.9e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AJZ76475.1 - 2.1e-05 24.2 0.1 4.3e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AJZ76475.1 - 3.1e-05 23.6 0.0 0.00011 21.8 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.6 AJZ76475.1 - 0.0015 17.8 0.1 2 7.6 0.0 2.6 1 1 2 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_5 PF13549.6 AJZ76475.1 - 0.0031 17.0 0.1 0.0081 15.6 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AJZ76475.1 - 0.065 12.8 0.1 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain Rimk_N PF18030.1 AJZ76475.1 - 0.096 13.1 0.1 0.53 10.7 0.0 2.1 1 1 1 2 2 2 0 RimK PreATP-grasp domain RRM_9 PF18444.1 AJZ76475.1 - 0.15 11.9 0.2 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif zinc_ribbon_4 PF13717.6 AJZ76476.1 - 0.00011 22.0 4.6 0.015 15.2 1.3 2.0 1 1 1 2 2 2 2 zinc-ribbon domain zf_UBZ PF18439.1 AJZ76476.1 - 0.0016 18.0 1.3 0.37 10.4 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DNA_RNApol_7kD PF03604.13 AJZ76476.1 - 0.0017 18.0 1.6 0.0071 16.0 1.5 1.8 1 1 1 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit BssC_TutF PF08201.11 AJZ76476.1 - 0.0027 17.7 0.2 0.078 13.0 0.1 2.0 2 0 0 2 2 2 1 BssC/TutF protein Zn-ribbon_8 PF09723.10 AJZ76476.1 - 0.0029 17.7 1.4 0.0054 16.8 1.4 1.4 1 1 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_5 PF13719.6 AJZ76476.1 - 0.004 16.9 0.5 0.2 11.4 0.1 2.1 2 0 0 2 2 2 1 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AJZ76476.1 - 0.004 16.6 0.4 0.0052 16.3 0.4 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding zf-HYPF PF07503.12 AJZ76476.1 - 0.0077 16.0 1.3 0.05 13.4 1.3 1.9 1 1 0 1 1 1 1 HypF finger zinc_ribbon_9 PF14369.6 AJZ76476.1 - 0.0081 16.4 1.0 0.016 15.4 1.0 1.4 1 1 0 1 1 1 1 zinc-ribbon zf-RING_7 PF02591.15 AJZ76476.1 - 0.01 16.0 0.4 0.027 14.7 0.0 1.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 AJZ76476.1 - 0.014 14.8 0.4 0.53 9.8 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 AJZ76476.1 - 0.018 15.0 1.7 0.036 14.0 1.7 1.5 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zinc-ribbons_6 PF07191.12 AJZ76476.1 - 0.022 14.7 0.4 0.061 13.3 0.4 1.6 1 1 0 1 1 1 0 zinc-ribbons HypA PF01155.19 AJZ76476.1 - 0.022 14.7 0.1 0.024 14.6 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_1 PF14446.6 AJZ76476.1 - 0.025 14.5 3.2 0.042 13.8 3.2 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.11 AJZ76476.1 - 0.04 13.8 0.2 0.052 13.5 0.2 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn_ribbon_recom PF13408.6 AJZ76476.1 - 0.046 14.2 0.4 0.87 10.1 0.0 2.1 1 1 0 2 2 2 0 Recombinase zinc beta ribbon domain ADK_lid PF05191.14 AJZ76476.1 - 0.047 13.7 0.4 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid A2L_zn_ribbon PF08792.10 AJZ76476.1 - 0.07 12.9 1.9 0.3 10.8 1.9 1.9 1 1 0 1 1 1 0 A2L zinc ribbon domain zf-TFIIB PF13453.6 AJZ76476.1 - 0.074 12.4 0.9 0.31 10.4 0.0 1.9 1 1 1 2 2 2 0 Transcription factor zinc-finger zf-C4_Topoisom PF01396.19 AJZ76476.1 - 0.1 12.4 0.5 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger CpXC PF14353.6 AJZ76476.1 - 0.33 11.0 1.6 1.4 9.0 0.1 1.9 1 1 1 2 2 2 0 CpXC protein HTH_AsnC-type PF13404.6 AJZ76477.1 - 1.4e-12 47.2 1.5 4.3e-12 45.6 1.0 2.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 AJZ76477.1 - 5.7e-12 45.4 0.2 8.5e-12 44.9 0.2 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AJZ76477.1 - 6.8e-11 41.6 1.2 3.1e-10 39.4 0.3 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding NapD PF03927.13 AJZ76477.1 - 0.0005 20.1 0.9 0.0038 17.2 0.3 2.1 1 1 1 2 2 2 2 NapD protein HTH_5 PF01022.20 AJZ76477.1 - 0.0022 17.8 0.1 0.0068 16.3 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AJZ76477.1 - 0.0025 17.7 0.5 0.0062 16.5 0.5 1.6 1 0 0 1 1 1 1 HTH domain Mga PF05043.13 AJZ76477.1 - 0.0034 17.9 0.1 0.0058 17.2 0.1 1.4 1 0 0 1 1 1 1 Mga helix-turn-helix domain Sigma70_r4 PF04545.16 AJZ76477.1 - 0.0068 15.9 0.1 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 AJZ76477.1 - 0.0084 16.0 0.1 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 MarR family MarR PF01047.22 AJZ76477.1 - 0.012 15.5 0.7 0.04 13.8 0.1 2.0 2 0 0 2 2 2 0 MarR family HTH_Mga PF08280.11 AJZ76477.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain ACT_4 PF13291.6 AJZ76477.1 - 0.033 14.8 1.3 2.5 8.8 0.5 2.3 2 0 0 2 2 2 0 ACT domain HTH_20 PF12840.7 AJZ76477.1 - 0.042 13.9 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain B-block_TFIIIC PF04182.12 AJZ76477.1 - 0.056 13.6 0.5 0.44 10.7 0.1 2.0 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC HTH_IclR PF09339.10 AJZ76477.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Aminotran_3 PF00202.21 AJZ76478.1 - 4.3e-119 397.8 0.0 5.3e-119 397.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AJZ76478.1 - 0.0026 17.0 0.0 0.0064 15.7 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II AA_kinase PF00696.28 AJZ76479.1 - 1e-38 133.3 2.9 1.1e-38 133.2 2.9 1.0 1 0 0 1 1 1 1 Amino acid kinase family DUF4947 PF16305.5 AJZ76479.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4947) Nudix_hydro PF18290.1 AJZ76480.1 - 0.0064 16.5 0.1 0.0078 16.2 0.1 1.3 1 0 0 1 1 1 1 Nudix hydrolase domain RimK PF08443.11 AJZ76481.1 - 8.7e-34 116.8 0.0 1.1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 AJZ76481.1 - 9.2e-10 38.2 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 AJZ76481.1 - 3.5e-09 36.3 0.3 2.7e-06 26.9 0.0 2.5 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp PF02222.22 AJZ76481.1 - 1.2e-06 28.2 0.0 3.3e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AJZ76481.1 - 1.2e-06 28.7 0.0 2.8e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AJZ76481.1 - 5.6e-06 26.0 0.0 1.3e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_5 PF13549.6 AJZ76481.1 - 0.00017 21.1 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 AJZ76481.1 - 0.00032 20.0 0.0 0.02 14.1 0.0 2.3 2 1 0 2 2 2 1 YheC/D like ATP-grasp GARS_A PF01071.19 AJZ76481.1 - 0.0079 16.0 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.6 AJZ76481.1 - 0.028 14.0 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.10 AJZ76481.1 - 0.035 13.7 0.0 0.083 12.4 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain zinc_ribbon_4 PF13717.6 AJZ76482.1 - 0.0029 17.5 0.3 0.013 15.4 0.1 1.9 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_9 PF14369.6 AJZ76482.1 - 0.0084 16.3 0.6 0.017 15.4 0.6 1.4 1 1 0 1 1 1 1 zinc-ribbon zf-RING_7 PF02591.15 AJZ76482.1 - 0.019 15.1 0.1 0.019 15.1 0.1 1.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain zinc_ribbon_5 PF13719.6 AJZ76482.1 - 0.023 14.4 0.7 0.042 13.6 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 AJZ76482.1 - 0.071 13.1 0.2 0.074 13.1 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 AJZ76482.1 - 0.088 12.8 0.3 0.12 12.3 0.3 1.3 1 1 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 AJZ76482.1 - 0.096 12.3 1.1 1.1 8.9 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DNA_RNApol_7kD PF03604.13 AJZ76482.1 - 0.11 12.2 3.6 1.4 8.7 0.2 2.6 1 1 2 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.10 AJZ76482.1 - 0.14 12.3 1.6 0.25 11.5 1.5 1.6 1 1 0 1 1 1 0 Zinc ribbon domain Prok-RING_1 PF14446.6 AJZ76482.1 - 0.15 12.0 2.7 0.2 11.6 2.7 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 A2L_zn_ribbon PF08792.10 AJZ76482.1 - 0.72 9.6 3.5 2.1 8.2 0.2 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Arginosuc_synth PF00764.19 AJZ76483.1 - 3.6e-157 523.6 0.0 4.1e-157 523.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.21 AJZ76483.1 - 0.00021 21.1 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 AJZ76483.1 - 0.00064 19.3 0.0 0.0014 18.2 0.1 1.6 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AJZ76483.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.5 1 1 0 1 1 1 0 PP-loop family NMT1_2 PF13379.6 AJZ76484.1 - 4.4e-28 98.7 0.0 6.1e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AJZ76484.1 - 8.1e-19 68.4 0.0 1.1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AJZ76484.1 - 3.9e-10 39.8 0.1 8.2e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein OpuAC PF04069.12 AJZ76484.1 - 1.1e-06 28.5 0.1 1.4e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system SBP_bac_3 PF00497.20 AJZ76484.1 - 8.3e-06 25.4 0.0 0.026 14.0 0.0 2.3 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 AJZ76484.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family ABC_tran PF00005.27 AJZ76485.1 - 1.4e-30 106.6 0.0 2.4e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AJZ76485.1 - 2.6e-09 37.3 0.1 0.0016 18.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AJZ76485.1 - 0.001 19.5 0.4 0.012 16.1 0.4 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 AJZ76485.1 - 0.0051 16.6 0.1 0.47 10.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 AJZ76485.1 - 0.0055 16.2 0.2 2.1 7.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AJZ76485.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 AJZ76485.1 - 0.014 15.2 0.1 0.032 14.0 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 AJZ76485.1 - 0.017 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 AJZ76485.1 - 0.021 14.8 0.0 0.058 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 AJZ76485.1 - 0.022 15.2 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AJZ76485.1 - 0.034 14.1 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 AJZ76485.1 - 0.038 13.9 0.1 0.37 10.7 0.1 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 AJZ76485.1 - 0.039 13.9 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 AJZ76485.1 - 0.042 14.1 0.1 0.062 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AJZ76485.1 - 0.052 13.9 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 AJZ76485.1 - 0.055 13.2 0.0 0.38 10.4 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 AJZ76485.1 - 0.073 13.2 0.1 0.094 12.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AJZ76485.1 - 0.076 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain T4SS-DNA_transf PF02534.14 AJZ76485.1 - 0.1 11.4 0.1 0.53 9.0 0.0 2.0 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer AAA_24 PF13479.6 AJZ76485.1 - 0.11 12.2 0.1 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AJZ76485.1 - 0.17 11.4 0.1 0.37 10.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AJZ76485.1 - 0.18 12.1 0.1 0.33 11.2 0.1 1.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit HemolysinCabind PF00353.19 AJZ76487.1 - 1.7e-24 85.4 66.4 4.3e-10 39.4 13.5 5.4 2 1 1 5 5 5 4 RTX calcium-binding nonapeptide repeat (4 copies) MFS_1 PF07690.16 AJZ76488.1 - 2.6e-28 99.0 73.7 9.7e-25 87.2 37.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AJZ76488.1 - 0.042 12.7 31.7 0.21 10.4 30.8 2.2 1 1 0 1 1 1 0 MFS_1 like family ParE_toxin PF05016.15 AJZ76489.1 - 0.0025 18.4 0.5 0.0029 18.2 0.5 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE HARP PF07443.13 AJZ76489.1 - 0.13 12.0 0.5 0.47 10.1 0.5 1.9 1 1 1 2 2 2 0 HepA-related protein (HARP) IGF2_C PF08365.11 AJZ76489.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide Pterin_bind PF00809.22 AJZ76490.1 - 2.6e-32 112.5 0.0 3.9e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme Met_synt_B12 PF02965.17 AJZ76490.1 - 1.7e-26 93.3 0.0 8.6e-26 91.0 0.0 2.2 2 1 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding PF02310.19 AJZ76490.1 - 8.7e-20 71.0 0.0 2.3e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 AJZ76490.1 - 2.6e-18 66.2 0.1 9.3e-18 64.4 0.1 2.0 1 0 0 1 1 1 1 B12 binding domain CdhD PF03599.16 AJZ76490.1 - 0.00012 20.9 0.0 0.00024 20.0 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit adh_short PF00106.25 AJZ76490.1 - 0.0084 15.6 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase DUF2922 PF11148.8 AJZ76490.1 - 0.54 10.0 2.7 1.3 8.8 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2922) DUF4917 PF16263.5 AJZ76491.1 - 0.046 13.1 0.4 0.048 13.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4917) DIRP PF06584.13 AJZ76491.1 - 0.063 13.5 0.3 0.2 11.8 0.0 1.8 1 1 1 2 2 2 0 DIRP DUF2732 PF10809.8 AJZ76491.1 - 0.077 12.9 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) S-methyl_trans PF02574.16 AJZ76492.1 - 8.9e-63 212.6 0.0 1e-62 212.4 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase MTHFR PF02219.17 AJZ76493.1 - 0.022 14.1 0.1 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Methylenetetrahydrofolate reductase NUDIX PF00293.28 AJZ76494.1 - 2e-12 47.3 0.0 2.4e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Ribosomal_L39 PF00832.20 AJZ76495.1 - 4.2e-20 71.1 8.4 4.9e-20 70.9 8.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein REV PF00424.18 AJZ76495.1 - 0.008 16.2 1.3 0.008 16.2 1.3 1.1 1 0 0 1 1 1 1 REV protein (anti-repression trans-activator protein) DUF3914 PF13053.6 AJZ76495.1 - 0.057 13.8 0.1 0.06 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) Ribosomal_L31e PF01198.19 AJZ76496.1 - 9.3e-18 64.3 0.4 9.3e-18 64.3 0.4 2.2 2 0 0 2 2 2 1 Ribosomal protein L31e GAGA_bind PF06217.12 AJZ76496.1 - 0.56 10.4 13.8 0.66 10.2 13.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family YqfQ PF14181.6 AJZ76496.1 - 6.8 6.9 16.7 9.8 6.3 16.7 1.3 1 0 0 1 1 1 0 YqfQ-like protein GRA6 PF05084.13 AJZ76496.1 - 7.9 6.4 8.8 12 5.8 8.8 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Peptidase_M10 PF00413.24 AJZ76497.1 - 0.00068 19.5 0.1 0.0013 18.6 0.1 1.6 1 1 0 1 1 1 1 Matrixin MG2 PF01835.19 AJZ76497.1 - 0.0014 19.1 0.0 0.0024 18.3 0.0 1.4 1 0 0 1 1 1 1 MG2 domain Peptidase_M66 PF10462.9 AJZ76497.1 - 0.0021 17.1 1.5 0.0046 16.0 1.5 1.5 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 AJZ76497.1 - 0.0085 16.6 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Big_3_5 PF16640.5 AJZ76497.1 - 0.0098 16.1 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) Filamin PF00630.19 AJZ76497.1 - 0.047 14.5 0.2 0.087 13.6 0.2 1.5 1 0 0 1 1 1 0 Filamin/ABP280 repeat Cadherin-like PF12733.7 AJZ76497.1 - 0.13 12.8 0.6 0.43 11.1 0.6 1.9 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain Reprolysin_4 PF13583.6 AJZ76497.1 - 0.42 10.2 1.6 0.47 10.1 0.4 1.8 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Radical_SAM PF04055.21 AJZ76498.1 - 3.9e-21 76.1 0.1 9.9e-21 74.8 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 AJZ76498.1 - 1.1e-16 60.7 0.0 2.9e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 AJZ76498.1 - 0.00029 20.8 0.1 0.001 19.0 0.0 2.0 2 0 0 2 2 2 1 TRAM domain TRAM_2 PF18693.1 AJZ76498.1 - 0.0034 17.5 0.1 0.012 15.7 0.1 2.0 1 0 0 1 1 1 1 TRAM domain B12-binding PF02310.19 AJZ76498.1 - 0.028 14.5 0.0 0.55 10.3 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain Lyase_1 PF00206.20 AJZ76499.1 - 1.8e-86 290.4 0.1 2.1e-86 290.2 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AJZ76499.1 - 6.9e-13 48.8 0.0 1.7e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus DUF2443 PF10398.9 AJZ76499.1 - 0.11 12.6 0.0 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) Cu-oxidase_3 PF07732.15 AJZ76500.1 - 6.5e-12 45.5 0.5 9.9e-10 38.5 0.1 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 AJZ76500.1 - 2.4 7.9 5.4 7.2 6.4 0.3 2.9 2 1 0 2 2 2 0 Multicopper oxidase 2-Hacid_dh_C PF02826.19 AJZ76502.1 - 8.9e-62 207.6 0.0 1.3e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AJZ76502.1 - 2.1e-28 98.6 0.4 2.4e-28 98.5 0.4 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AJZ76502.1 - 2.8e-05 24.3 0.3 0.00024 21.3 0.0 2.2 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 AJZ76502.1 - 0.0055 17.2 0.1 0.25 11.9 0.0 3.0 2 1 0 2 2 2 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 AJZ76502.1 - 0.0087 16.1 0.2 0.027 14.6 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain LXG PF04740.12 AJZ76502.1 - 0.072 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily FAP PF07174.11 AJZ76503.1 - 0.029 13.8 5.0 0.038 13.4 5.0 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CLIP_1 PF18322.1 AJZ76503.1 - 0.074 13.1 3.3 0.13 12.4 0.4 2.4 2 1 0 2 2 2 0 Serine protease Clip domain PPAF-2 TIL PF01826.17 AJZ76503.1 - 0.17 12.2 2.4 7.3 6.9 0.7 2.7 2 1 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Cluap1 PF10234.9 AJZ76505.1 - 0.0044 16.5 7.4 0.0044 16.5 7.4 2.5 1 1 0 2 2 2 1 Clusterin-associated protein-1 DivIC PF04977.15 AJZ76505.1 - 0.0055 16.4 15.1 0.09 12.6 1.1 3.4 3 0 0 3 3 3 2 Septum formation initiator DUF2937 PF11157.8 AJZ76505.1 - 1.3 8.7 5.2 0.26 11.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF1664 PF07889.12 AJZ76505.1 - 1.9 8.6 15.4 1.6 8.7 1.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HrpB7 PF09486.10 AJZ76505.1 - 2.5 8.5 12.9 0.81 10.1 0.8 2.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) PspA_IM30 PF04012.12 AJZ76505.1 - 6.1 6.3 24.5 0.99 8.9 7.8 2.7 2 1 0 3 3 3 0 PspA/IM30 family Ribosomal_L15e PF00827.17 AJZ76506.1 - 2.9e-43 147.8 4.4 3.5e-43 147.6 4.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Redoxin PF08534.10 AJZ76507.1 - 1.7e-07 31.1 0.1 0.00032 20.4 0.0 2.1 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.21 AJZ76507.1 - 2.8e-07 30.5 0.1 8.8e-05 22.4 0.0 2.5 2 1 0 2 2 2 2 AhpC/TSA family GSHPx PF00255.19 AJZ76507.1 - 0.054 13.1 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione peroxidase Thioredoxin_2 PF13098.6 AJZ76507.1 - 0.13 12.7 0.4 1.1 9.7 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin-like domain DUF553 PF04473.12 AJZ76507.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like domain HEAT_2 PF13646.6 AJZ76508.1 - 7.3e-36 122.4 0.0 1.8e-16 60.3 0.1 2.1 1 1 2 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 AJZ76508.1 - 2.6e-14 52.4 0.0 6.4e-06 26.4 0.1 3.6 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat HEAT PF02985.22 AJZ76508.1 - 1.8e-13 49.5 0.0 0.014 15.6 0.0 4.1 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.6 AJZ76508.1 - 3.6e-09 36.9 0.0 0.03 14.8 0.0 3.9 4 0 0 4 4 4 3 HEAT-like repeat Cnd1 PF12717.7 AJZ76508.1 - 8.8e-05 22.6 0.0 0.022 14.8 0.0 2.9 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 AJZ76508.1 - 0.00043 20.2 0.0 0.031 14.3 0.0 2.9 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 AJZ76508.1 - 0.14 10.6 0.0 5.1 5.5 0.0 2.2 1 1 0 2 2 2 0 Adaptin N terminal region AAA_15 PF13175.6 AJZ76509.1 - 5.5e-21 75.7 41.9 2.7e-13 50.4 19.7 2.3 1 1 1 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 AJZ76509.1 - 5.8e-20 72.7 25.0 5.8e-20 72.7 25.0 4.0 1 1 2 3 3 2 1 AAA domain SMC_N PF02463.19 AJZ76509.1 - 5.1e-19 68.6 23.0 1.1e-11 44.6 0.4 3.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AJZ76509.1 - 4.8e-14 52.9 2.0 3.4e-07 30.4 0.3 2.8 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AJZ76509.1 - 6.2e-09 35.5 0.1 1.3e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 AJZ76509.1 - 2.8e-08 33.6 1.4 2.8e-08 33.6 1.4 2.9 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 AJZ76509.1 - 2.8e-06 27.5 0.0 6.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 AJZ76509.1 - 0.0025 18.3 19.0 0.0063 17.0 0.0 4.7 2 1 0 2 2 1 1 ABC transporter RsgA_GTPase PF03193.16 AJZ76509.1 - 0.0089 15.9 0.0 0.0089 15.9 0.0 4.1 4 1 0 4 4 4 1 RsgA GTPase PHF5 PF03660.14 AJZ76509.1 - 0.021 15.0 0.6 0.065 13.4 0.0 2.0 2 0 0 2 2 2 0 PHF5-like protein Fez1 PF06818.15 AJZ76509.1 - 0.34 11.4 46.4 0.11 13.0 10.2 4.6 2 1 3 5 5 5 0 Fez1 MukB PF04310.12 AJZ76509.1 - 0.55 10.0 0.0 0.55 10.0 0.0 3.5 4 0 0 4 4 4 0 MukB N-terminal AAA_16 PF13191.6 AJZ76509.1 - 4.2 7.7 5.9 2.1 8.7 0.3 3.1 3 2 0 3 3 3 0 AAA ATPase domain Spc7 PF08317.11 AJZ76509.1 - 4.9 5.9 50.7 0.064 12.1 3.4 4.2 2 2 2 4 4 4 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 AJZ76509.1 - 8.1 6.7 49.6 1.8 8.8 11.8 5.4 3 3 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 AJZ76509.1 - 8.3 6.9 23.0 0.41 11.1 0.4 5.9 3 3 2 5 5 5 0 Nucleopolyhedrovirus P10 protein vATP-synt_AC39 PF01992.16 AJZ76510.1 - 8.5e-48 163.6 7.6 1e-47 163.3 7.6 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DrrA_P4M PF14860.6 AJZ76510.1 - 3.6 7.5 9.4 9.1 6.2 0.5 3.5 4 1 0 4 4 4 0 DrrA phosphatidylinositol 4-phosphate binding domain AsnC_trans_reg PF01037.21 AJZ76511.1 - 5.8e-16 58.2 0.8 3.6e-08 33.3 0.2 2.1 2 0 0 2 2 2 2 Lrp/AsnC ligand binding domain NurA PF09376.10 AJZ76512.1 - 1.7e-16 60.7 0.0 2.6e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 NurA domain WW PF00397.26 AJZ76512.1 - 0.098 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 WW domain NadA PF02445.16 AJZ76513.1 - 5.2e-115 383.7 2.2 6e-115 383.5 2.2 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein ApeC PF16977.5 AJZ76513.1 - 0.05 13.5 0.2 0.14 12.0 0.0 1.8 1 1 1 2 2 2 0 C-terminal domain of apextrin HATPase_c PF02518.26 AJZ76515.1 - 7.1e-22 78.0 0.4 1.3e-21 77.2 0.4 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJZ76515.1 - 6.2e-12 45.4 0.2 6.2e-12 45.4 0.2 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJZ76515.1 - 2.9e-05 23.9 0.0 6.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 GHKL domain DUF5101 PF17031.5 AJZ76515.1 - 0.042 14.0 0.0 0.042 14.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) Cortex-I_coil PF09304.10 AJZ76515.1 - 0.14 12.4 10.0 0.26 11.5 9.9 1.6 1 1 0 1 1 1 0 Cortexillin I, coiled coil OmpH PF03938.14 AJZ76515.1 - 0.43 10.9 8.7 0.76 10.1 8.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF883 PF05957.13 AJZ76515.1 - 0.67 10.6 5.8 7 7.3 0.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Rho_Binding PF08912.11 AJZ76515.1 - 0.76 10.6 10.9 1.9 9.3 10.9 1.7 1 0 0 1 1 1 0 Rho Binding Apolipoprotein PF01442.18 AJZ76515.1 - 1.8 8.4 13.7 2.8 7.7 13.7 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1043 PF06295.12 AJZ76515.1 - 2.8 8.0 8.3 5 7.1 8.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) SHS2_Rpb7-N PF03876.17 AJZ76516.1 - 1.4e-16 60.6 0.0 3.6e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 AJZ76516.1 - 3.1e-12 46.7 1.2 3.5e-12 46.5 0.0 1.7 2 0 0 2 2 2 1 S1 RNA binding domain S1_2 PF13509.6 AJZ76516.1 - 0.027 14.5 0.0 0.077 13.1 0.0 1.8 1 1 1 2 2 2 0 S1 domain H_PPase PF03030.16 AJZ76517.1 - 9.4e-221 734.9 49.8 1.1e-220 734.7 49.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase HxlR PF01638.17 AJZ76518.1 - 1.9e-19 69.3 0.3 2.2e-19 69.1 0.3 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.22 AJZ76518.1 - 2.2e-08 33.9 0.1 3.5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AJZ76518.1 - 8.8e-06 25.5 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 AJZ76518.1 - 2e-05 24.7 0.0 2.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain PadR PF03551.14 AJZ76518.1 - 9.3e-05 22.3 0.2 0.00013 21.8 0.2 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family DUF4423 PF14394.6 AJZ76518.1 - 0.00015 21.5 0.1 0.00018 21.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_20 PF12840.7 AJZ76518.1 - 0.00024 21.1 0.0 0.00032 20.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AJZ76518.1 - 0.00033 20.5 0.0 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 AJZ76518.1 - 0.00069 19.8 0.1 0.00098 19.3 0.1 1.2 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 AJZ76518.1 - 0.00073 19.0 0.1 0.0019 17.7 0.1 1.8 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding Penicillinase_R PF03965.16 AJZ76518.1 - 0.00082 19.7 0.1 0.0011 19.4 0.1 1.2 1 0 0 1 1 1 1 Penicillinase repressor HTH_Crp_2 PF13545.6 AJZ76518.1 - 0.00085 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AJZ76518.1 - 0.0017 18.6 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator HTH_5 PF01022.20 AJZ76518.1 - 0.0019 18.0 0.1 0.0027 17.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family GntR PF00392.21 AJZ76518.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF2513 PF10711.9 AJZ76518.1 - 0.015 15.5 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_23 PF13384.6 AJZ76518.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain B-block_TFIIIC PF04182.12 AJZ76518.1 - 0.016 15.4 0.1 0.022 14.9 0.1 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_27 PF13463.6 AJZ76518.1 - 0.042 14.3 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Replic_Relax PF13814.6 AJZ76518.1 - 0.046 13.8 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation SMC_Nse1 PF07574.13 AJZ76518.1 - 0.047 13.6 0.1 0.086 12.7 0.0 1.4 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex LexA_DNA_bind PF01726.16 AJZ76518.1 - 0.066 13.0 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 LexA DNA binding domain Mnd1 PF03962.15 AJZ76518.1 - 0.079 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Mnd1 HTH domain HTH_DeoR PF08220.12 AJZ76518.1 - 0.088 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain FUR PF01475.19 AJZ76518.1 - 0.099 12.8 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_IclR PF09339.10 AJZ76518.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF2024 PF09630.10 AJZ76519.1 - 5.5e-36 122.3 1.4 6.1e-36 122.2 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) CCG PF02754.16 AJZ76519.1 - 0.042 14.1 0.1 0.06 13.6 0.1 1.2 1 0 0 1 1 1 0 Cysteine-rich domain Haem_bd PF14376.6 AJZ76519.1 - 0.073 13.0 0.1 0.087 12.8 0.1 1.2 1 0 0 1 1 1 0 Haem-binding domain AAA PF00004.29 AJZ76520.1 - 2.2e-92 306.4 0.0 2.6e-48 163.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AJZ76520.1 - 1e-28 98.8 1.0 1.1e-13 50.7 0.2 2.7 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 AJZ76520.1 - 1.4e-25 89.3 0.3 7.1e-25 87.0 0.3 2.3 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 AJZ76520.1 - 2.5e-16 59.8 0.0 1.2e-08 34.9 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AJZ76520.1 - 2.8e-13 50.6 0.1 0.00068 20.1 0.0 4.5 3 2 0 4 4 3 2 AAA ATPase domain AAA_2 PF07724.14 AJZ76520.1 - 1e-12 48.5 0.0 1.2e-07 32.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 AJZ76520.1 - 1.8e-11 44.2 0.0 4.2e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 AJZ76520.1 - 1e-10 42.1 0.2 0.032 14.5 0.0 4.3 3 1 1 4 4 4 2 AAA domain AAA_5 PF07728.14 AJZ76520.1 - 1.3e-10 41.4 0.1 0.00036 20.6 0.0 4.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AJZ76520.1 - 5.7e-10 39.5 0.0 0.00099 19.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 AJZ76520.1 - 1.7e-09 37.3 0.3 4.3e-09 36.0 0.3 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.22 AJZ76520.1 - 5.3e-09 36.4 0.0 0.0017 18.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 AJZ76520.1 - 1.1e-08 35.2 0.0 0.0049 16.8 0.0 3.6 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 AJZ76520.1 - 7.4e-08 33.0 0.0 0.0061 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 AJZ76520.1 - 1e-07 31.7 0.0 0.5 9.9 0.0 4.0 4 0 0 4 4 4 2 AAA domain Mg_chelatase PF01078.21 AJZ76520.1 - 2.5e-07 30.3 0.2 0.021 14.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 AJZ76520.1 - 2.8e-07 31.1 0.0 0.021 15.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter IstB_IS21 PF01695.17 AJZ76520.1 - 4.6e-07 29.7 0.0 0.039 13.7 0.0 3.1 3 1 1 4 4 3 2 IstB-like ATP binding protein Rad17 PF03215.15 AJZ76520.1 - 8e-07 29.2 0.5 0.026 14.4 0.0 3.3 2 2 0 2 2 2 2 Rad17 P-loop domain TIP49 PF06068.13 AJZ76520.1 - 1.6e-06 27.6 0.0 0.004 16.4 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_28 PF13521.6 AJZ76520.1 - 2.5e-06 27.8 0.0 0.076 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 AJZ76520.1 - 6.1e-06 26.1 0.0 0.11 12.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain ATPase PF06745.13 AJZ76520.1 - 6.4e-06 25.7 0.7 0.24 10.7 0.0 3.7 2 2 2 4 4 4 2 KaiC Zeta_toxin PF06414.12 AJZ76520.1 - 1.7e-05 24.2 0.0 0.038 13.3 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.12 AJZ76520.1 - 1.8e-05 24.7 0.0 0.23 11.4 0.0 3.4 3 0 0 3 3 3 2 NACHT domain TsaE PF02367.17 AJZ76520.1 - 2.2e-05 24.4 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 AJZ76520.1 - 3.6e-05 23.9 0.0 0.12 12.5 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 AJZ76520.1 - 7.6e-05 22.6 0.0 0.037 13.7 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 AJZ76520.1 - 8.2e-05 22.1 0.0 0.17 11.3 0.0 3.3 2 1 1 3 3 3 1 PhoH-like protein AAA_7 PF12775.7 AJZ76520.1 - 0.00022 20.8 0.0 0.37 10.3 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 AJZ76520.1 - 0.00025 20.8 0.0 1.2 8.8 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.6 AJZ76520.1 - 0.00081 19.8 0.0 2.3 8.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 AJZ76520.1 - 0.0011 18.2 0.0 0.39 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 AJZ76520.1 - 0.0012 18.1 0.0 1.7 7.8 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Parvo_NS1 PF01057.17 AJZ76520.1 - 0.0017 17.5 0.0 1.7 7.6 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 AJZ76520.1 - 0.0024 17.7 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_11 PF13086.6 AJZ76520.1 - 0.0036 17.1 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 AJZ76520.1 - 0.0038 17.2 0.0 1.4 8.9 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 AJZ76520.1 - 0.0048 16.8 0.0 3.6 7.5 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 AJZ76520.1 - 0.0059 15.9 0.0 0.61 9.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) SRPRB PF09439.10 AJZ76520.1 - 0.012 15.1 0.0 2.3 7.6 0.0 2.7 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit Adeno_IVa2 PF02456.15 AJZ76520.1 - 0.023 13.5 0.4 0.96 8.2 0.0 2.5 3 0 0 3 3 2 0 Adenovirus IVa2 protein KAP_NTPase PF07693.14 AJZ76520.1 - 0.023 13.9 0.0 0.81 8.9 0.0 2.9 2 1 0 2 2 2 0 KAP family P-loop domain ATP-synt_ab PF00006.25 AJZ76520.1 - 0.028 14.1 0.0 7.9 6.1 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 AJZ76520.1 - 0.03 14.6 0.1 13 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain RNA_pol_Rpb5_C PF01191.19 AJZ76520.1 - 0.081 12.8 0.1 11 5.9 0.1 2.8 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain NTPase_1 PF03266.15 AJZ76520.1 - 0.092 12.7 0.3 39 4.1 0.0 3.5 2 2 1 3 3 3 0 NTPase DAP3 PF10236.9 AJZ76520.1 - 0.16 11.1 0.0 6.9 5.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ADH_N PF08240.12 AJZ76521.1 - 2.6e-28 98.1 0.4 4.3e-28 97.4 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AJZ76521.1 - 2.2e-18 66.5 0.2 3.3e-18 65.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 AJZ76521.1 - 3e-05 23.4 0.6 6.2e-05 22.4 0.3 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 AJZ76521.1 - 0.00022 22.3 0.0 0.00043 21.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CoA_binding PF02629.19 AJZ76521.1 - 0.21 12.3 1.8 0.77 10.5 1.8 2.0 1 1 0 1 1 1 0 CoA binding domain Usp PF00582.26 AJZ76523.1 - 1e-29 103.8 0.0 1.2e-29 103.7 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family HpcH_HpaI PF03328.14 AJZ76523.1 - 0.025 13.7 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family CoA_binding PF02629.19 AJZ76524.1 - 5e-22 78.4 3.7 5.8e-22 78.2 1.4 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 AJZ76524.1 - 2.8e-12 46.7 0.5 9.2e-12 45.0 0.1 2.0 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 AJZ76524.1 - 2e-08 34.1 0.0 3.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AJZ76524.1 - 1e-05 26.0 0.0 1.7e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 AJZ76524.1 - 0.015 16.1 0.2 0.031 15.1 0.2 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ribul_P_3_epim PF00834.19 AJZ76524.1 - 0.025 14.0 0.1 0.044 13.2 0.1 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family CARDB PF07705.11 AJZ76525.1 - 0.00092 19.4 0.1 0.0036 17.6 0.0 1.9 2 0 0 2 2 2 1 CARDB PHTB1_C PF14728.6 AJZ76525.1 - 0.053 12.6 0.5 0.8 8.7 0.2 2.1 2 0 0 2 2 2 0 PTHB1 C-terminus Transglut_C PF00927.22 AJZ76525.1 - 0.081 13.1 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain EamA PF00892.20 AJZ76527.1 - 2.2e-30 105.6 36.1 2.5e-18 66.6 15.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family Acyl_transf_3 PF01757.22 AJZ76527.1 - 0.0053 15.9 21.3 0.087 11.9 14.4 2.5 1 1 1 2 2 2 2 Acyltransferase family DUF2663 PF10864.8 AJZ76527.1 - 8 6.9 8.4 1.8 9.0 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) RMMBL PF07521.12 AJZ76528.1 - 0.0026 17.7 0.0 0.0071 16.3 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain DRMBL PF07522.14 AJZ76528.1 - 0.007 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase AsnC_trans_reg PF01037.21 AJZ76529.1 - 3.1e-09 36.7 0.0 3.6e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HD_4 PF13328.6 AJZ76530.1 - 0.00018 21.3 0.0 0.00024 20.9 0.0 1.1 1 0 0 1 1 1 1 HD domain zf-C4H2 PF10146.9 AJZ76530.1 - 0.0068 16.7 1.8 0.0082 16.5 1.8 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein Arginase PF00491.21 AJZ76531.1 - 1.4e-58 198.6 0.1 1.7e-58 198.4 0.1 1.0 1 0 0 1 1 1 1 Arginase family DUF4147 PF13660.6 AJZ76532.1 - 3.9e-67 226.2 0.3 6.3e-67 225.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 AJZ76532.1 - 1.4e-29 102.5 0.2 2.9e-29 101.5 0.2 1.6 1 0 0 1 1 1 1 MOFRL family Adenine_deam_C PF13382.6 AJZ76532.1 - 0.048 13.0 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Adenine deaminase C-terminal domain CPSase_L_D2 PF02786.17 AJZ76533.1 - 8.6e-104 345.6 0.0 3.3e-73 245.7 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 AJZ76533.1 - 7.4e-38 129.6 0.1 1.8e-37 128.4 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 AJZ76533.1 - 1.8e-17 63.5 0.1 3.5e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AJZ76533.1 - 3.7e-15 56.0 0.2 1.1e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 AJZ76533.1 - 1.6e-14 53.8 0.1 9.7e-14 51.3 0.1 2.5 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.6 AJZ76533.1 - 1.1e-13 51.0 0.0 6.2e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 AJZ76533.1 - 1.3e-09 38.1 0.1 0.00019 21.3 0.0 2.8 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 AJZ76533.1 - 0.00011 22.3 0.2 0.25 11.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 AJZ76533.1 - 0.00015 21.3 0.0 0.056 12.9 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp domain ATP-grasp_2 PF08442.10 AJZ76533.1 - 0.00094 18.8 0.1 0.0052 16.4 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Semialdhyde_dh PF01118.24 AJZ76533.1 - 0.13 12.7 0.0 0.37 11.3 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TFIIB PF00382.19 AJZ76534.1 - 1.2e-34 118.2 1.5 1.7e-18 66.4 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJZ76534.1 - 0.00036 20.0 0.2 0.00072 19.0 0.2 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zinc_ribbon_6 PF14599.6 AJZ76535.1 - 0.012 15.6 1.9 0.04 13.9 2.0 1.8 1 1 1 2 2 2 0 Zinc-ribbon Metallophos PF00149.28 AJZ76536.1 - 1.4e-07 32.2 0.2 2.5e-07 31.4 0.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AJZ76536.1 - 0.00011 22.5 0.1 0.00018 21.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cation_ATPase_C PF00689.21 AJZ76537.1 - 0.3 10.8 8.6 0.61 9.8 8.4 1.7 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Sensor PF13796.6 AJZ76537.1 - 1.3 9.1 7.7 2.2 8.3 0.4 2.5 2 1 0 2 2 2 0 Putative sensor DHHC PF01529.20 AJZ76537.1 - 1.4 9.0 4.5 4.4 7.4 3.3 2.3 2 1 0 2 2 2 0 DHHC palmitoyltransferase Syndecan PF01034.20 AJZ76537.1 - 3.3 7.7 5.1 4.2 7.4 0.5 2.7 2 0 0 2 2 2 0 Syndecan domain ALS_ss_C PF10369.9 AJZ76538.1 - 1.8e-24 85.7 0.5 5.1e-22 77.9 0.0 2.3 2 1 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.25 AJZ76538.1 - 6.2e-15 54.7 0.1 1.6e-14 53.3 0.1 1.7 1 1 1 2 2 2 1 ACT domain ACT_5 PF13710.6 AJZ76538.1 - 5.3e-12 45.4 0.1 9.8e-12 44.5 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AJZ76538.1 - 2.5e-06 28.0 0.4 5e-06 27.0 0.4 1.5 1 0 0 1 1 1 1 ACT domain NIL PF09383.10 AJZ76538.1 - 0.018 14.9 0.1 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 NIL domain SLS PF14611.6 AJZ76538.1 - 0.045 13.6 0.4 0.052 13.4 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Med18 PF09637.10 AJZ76538.1 - 0.047 13.5 0.1 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 Med18 protein Laminin_EGF PF00053.24 AJZ76539.1 - 0.0058 16.7 0.7 0.006 16.7 0.7 1.1 1 0 0 1 1 1 1 Laminin EGF domain DZR PF12773.7 AJZ76539.1 - 0.014 15.4 1.3 0.017 15.1 1.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon DUF2321 PF10083.9 AJZ76539.1 - 0.18 11.4 1.9 0.29 10.8 1.7 1.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zinc_ribbon_6 PF14599.6 AJZ76539.1 - 0.21 11.6 2.4 0.82 9.7 2.4 1.8 1 1 0 1 1 1 0 Zinc-ribbon FeoB_C PF07664.12 AJZ76539.1 - 0.28 10.9 1.2 0.32 10.7 1.2 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus DUF872 PF05915.12 AJZ76540.1 - 0.0087 16.2 0.4 0.0098 16.0 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF2207 PF09972.9 AJZ76540.1 - 0.1 11.3 1.0 0.12 11.1 1.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) E1-E2_ATPase PF00122.20 AJZ76540.1 - 0.46 10.0 1.3 0.53 9.8 1.3 1.0 1 0 0 1 1 1 0 E1-E2 ATPase HIT PF01230.23 AJZ76542.1 - 3.7e-24 85.3 0.5 4.7e-24 85.0 0.5 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AJZ76542.1 - 1.9e-13 50.9 0.3 2.5e-13 50.5 0.3 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 AJZ76542.1 - 0.0022 17.9 0.2 0.003 17.4 0.2 1.3 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Aminotran_3 PF00202.21 AJZ76543.1 - 1.3e-57 195.3 0.2 1.8e-57 194.9 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-III MazE_antitoxin PF04014.18 AJZ76544.1 - 0.00036 20.4 0.2 0.00036 20.4 0.2 1.8 2 0 0 2 2 2 1 Antidote-toxin recognition MazE, bacterial antitoxin DUF2207 PF09972.9 AJZ76544.1 - 0.072 11.8 0.3 0.085 11.6 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3949 PF13133.6 AJZ76544.1 - 0.15 12.5 1.4 1.8 9.1 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3949) AATF-Che1 PF13339.6 AJZ76545.1 - 0.0017 19.0 3.5 0.003 18.3 3.5 1.3 1 1 0 1 1 1 1 Apoptosis antagonizing transcription factor Effector_1 PF04518.12 AJZ76545.1 - 0.01 15.0 0.6 0.01 15.0 0.6 1.0 1 0 0 1 1 1 0 Effector from type III secretion system LAGLIDADG_WhiA PF14527.6 AJZ76545.1 - 0.048 13.7 0.2 0.069 13.2 0.2 1.4 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain GTP_EFTU_D2 PF03144.25 AJZ76546.1 - 1.4e-10 41.4 0.6 3.6e-10 40.1 0.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Pilin_N PF07790.11 AJZ76547.1 - 0.024 15.5 2.8 0.035 15.0 0.3 2.2 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal LTD PF00932.19 AJZ76547.1 - 0.043 14.2 0.1 0.093 13.1 0.1 1.6 1 1 0 1 1 1 0 Lamin Tail Domain Monooxygenase_B PF04744.12 AJZ76547.1 - 0.061 12.1 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Monooxygenase subunit B protein Big_3 PF07523.12 AJZ76547.1 - 0.078 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) dCMP_cyt_deam_1 PF00383.23 AJZ76548.1 - 1.4e-27 95.5 2.1 1.7e-27 95.2 2.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AJZ76548.1 - 2.5e-16 59.7 0.3 3.1e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 AJZ76548.1 - 0.054 13.6 0.1 0.081 13.0 0.1 1.3 1 0 0 1 1 1 0 APOBEC3 Helicase_C PF00271.31 AJZ76549.1 - 6.5e-22 78.0 0.1 1.6e-21 76.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AJZ76549.1 - 5e-19 68.9 0.0 1.2e-18 67.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AJZ76549.1 - 8.3e-18 64.8 0.0 1.9e-17 63.6 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 AJZ76549.1 - 0.00077 19.5 0.0 0.0034 17.4 0.0 2.1 2 1 0 2 2 2 1 Flavivirus DEAD domain SNF2_N PF00176.23 AJZ76549.1 - 0.031 13.0 0.0 0.051 12.3 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF2075 PF09848.9 AJZ76549.1 - 0.035 13.3 0.0 0.069 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 AJZ76549.1 - 0.046 14.0 0.2 0.25 11.7 0.2 2.2 1 1 0 1 1 1 0 AAA domain SWI2_SNF2 PF18766.1 AJZ76549.1 - 0.064 12.9 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase UbiA PF01040.18 AJZ76550.1 - 2.8e-26 92.3 7.0 2.8e-26 92.3 7.0 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family EI24 PF07264.11 AJZ76550.1 - 8.8 6.5 14.1 72 3.6 14.1 2.1 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Radical_SAM PF04055.21 AJZ76551.1 - 9e-19 68.5 0.0 1.8e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AJZ76551.1 - 1.2e-05 25.4 0.0 2.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AJZ76551.1 - 0.025 14.9 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Chorismate_bind PF00425.18 AJZ76552.1 - 5.8e-93 311.2 0.0 3e-91 305.6 0.0 2.3 2 1 1 3 3 3 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 AJZ76552.1 - 1.4e-18 67.5 0.3 1.9e-17 63.8 0.1 2.4 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region ETRAMP PF09716.10 AJZ76553.1 - 0.094 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) eRF1_2 PF03464.15 AJZ76554.1 - 5.7e-31 107.6 0.0 9.9e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 AJZ76554.1 - 1.1e-17 64.5 0.1 3.2e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 AJZ76554.1 - 2e-11 44.0 0.0 3.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 AJZ76554.1 - 1e-09 38.8 0.0 1.8e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 AJZ76554.1 - 3.4e-08 33.8 0.0 5.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Ski_Sno PF02437.17 AJZ76554.1 - 0.1 12.3 0.3 0.23 11.2 0.3 1.6 1 0 0 1 1 1 0 SKI/SNO/DAC family CbtB PF09489.10 AJZ76555.1 - 5.1e-13 48.9 1.7 7.6e-13 48.3 1.7 1.3 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) SecE PF00584.20 AJZ76555.1 - 0.24 11.3 2.3 0.36 10.8 2.3 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Tad PF13400.6 AJZ76555.1 - 0.42 11.0 3.0 0.37 11.1 2.0 1.4 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF5640 PF18692.1 AJZ76556.1 - 0.084 12.9 0.1 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5640) HATPase_c PF02518.26 AJZ76557.1 - 8.7e-24 84.2 1.0 2.4e-23 82.8 0.2 2.0 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJZ76557.1 - 1.1e-13 51.0 0.3 2.1e-13 50.1 0.3 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJZ76557.1 - 8e-07 28.9 0.1 1.5e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AJZ76557.1 - 1.1e-05 25.3 0.1 1.7e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim_4 PF13662.6 AJZ76558.1 - 0.00017 22.0 0.0 0.097 13.2 0.0 2.2 2 0 0 2 2 2 2 Toprim domain Toprim PF01751.22 AJZ76558.1 - 0.00054 20.1 0.1 0.021 15.0 0.1 2.4 1 1 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AJZ76558.1 - 0.003 17.9 0.0 0.0055 17.1 0.0 1.5 1 1 0 1 1 1 1 Toprim-like Lipoprotein_19 PF13617.6 AJZ76559.1 - 0.15 11.9 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 YnbE-like lipoprotein HD_3 PF13023.6 AJZ76561.1 - 6.8e-39 133.4 0.1 7.7e-39 133.3 0.1 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 AJZ76561.1 - 1.1e-17 64.3 0.3 1.7e-17 63.8 0.3 1.3 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 AJZ76561.1 - 2e-08 34.5 0.4 5.1e-08 33.2 0.4 1.7 1 1 0 1 1 1 1 HD domain TTSSLRR PF12468.8 AJZ76561.1 - 0.003 17.7 0.3 0.0046 17.2 0.3 1.4 1 1 0 1 1 1 1 Type III secretion system leucine rich repeat protein T3SS_needle_reg PF09025.10 AJZ76561.1 - 0.0037 17.2 0.4 0.0059 16.6 0.4 1.3 1 0 0 1 1 1 1 YopR, type III needle-polymerisation regulator Nrf1_DNA-bind PF10491.9 AJZ76561.1 - 0.021 14.5 0.8 0.042 13.6 0.2 1.7 1 1 1 2 2 2 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 DUF1213 PF06740.12 AJZ76561.1 - 0.18 12.4 0.3 6 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) Guanylate_cyc PF00211.20 AJZ76563.1 - 3.2e-16 59.5 0.1 4.4e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Arc_PepC_II PF06847.11 AJZ76564.1 - 1.8e-11 44.4 1.1 2.1e-10 40.9 0.4 2.6 2 1 0 2 2 2 1 Archaeal Peptidase A24 C-terminus Type II Peptidase_A24 PF01478.18 AJZ76564.1 - 8e-05 23.0 9.9 8e-05 23.0 9.9 1.7 2 0 0 2 2 2 1 Type IV leader peptidase family RIF5_SNase_1 PF18187.1 AJZ76564.1 - 0.097 12.4 0.7 2.4 7.9 0.0 2.4 3 0 0 3 3 3 0 TbRIF5 SNase domain 1 HATPase_c PF02518.26 AJZ76565.1 - 1.3e-21 77.2 0.3 3.6e-21 75.8 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJZ76565.1 - 2.1e-12 46.9 1.9 2.7e-12 46.5 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJZ76565.1 - 7.3e-06 25.8 0.2 1.8e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 AJZ76565.1 - 0.00023 21.0 0.0 0.00051 19.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AJZ76565.1 - 0.0004 20.3 0.0 0.00081 19.3 0.0 1.5 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain TerD PF02342.18 AJZ76565.1 - 0.014 14.8 2.6 0.075 12.5 2.6 2.0 1 1 0 1 1 1 0 TerD domain UPF0147 PF03685.13 AJZ76565.1 - 0.018 15.1 2.0 0.033 14.2 1.1 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0147) BRCT_2 PF16589.5 AJZ76565.1 - 0.025 15.0 0.3 0.39 11.2 0.0 2.4 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Hpr_kinase_N PF02603.16 AJZ76566.1 - 0.0081 16.2 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 HPr Serine kinase N terminus TrmB PF01978.19 AJZ76566.1 - 0.019 14.8 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FUR PF01475.19 AJZ76566.1 - 0.039 14.1 0.1 0.046 13.9 0.1 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_20 PF12840.7 AJZ76566.1 - 0.075 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 AJZ76566.1 - 0.081 13.0 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF742 PF05331.11 AJZ76566.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF742) PALP PF00291.25 AJZ76567.1 - 1.8e-49 168.8 0.0 2.2e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PK_C PF02887.16 AJZ76567.1 - 0.15 12.3 1.4 2.4 8.4 0.6 2.3 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain DsbD PF02683.15 AJZ76568.1 - 2.1e-49 168.3 19.6 2.5e-49 168.1 19.6 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 AJZ76568.1 - 6.1e-06 26.3 15.4 8.8e-06 25.8 15.1 1.4 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF2781 PF10914.8 AJZ76568.1 - 0.0029 18.0 0.8 0.0092 16.4 0.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) NUDIX PF00293.28 AJZ76569.1 - 1.8e-12 47.4 0.0 2.1e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AJZ76569.1 - 0.0034 17.3 0.0 0.0045 17.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ribosomal_S8 PF00410.19 AJZ76570.1 - 8.8e-21 74.2 0.0 1e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Proteasome PF00227.26 AJZ76571.1 - 9.2e-54 181.8 0.2 1.2e-53 181.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AJZ76571.1 - 3.5e-14 52.1 0.7 1.3e-13 50.3 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature TFIIB PF00382.19 AJZ76571.1 - 0.098 12.7 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat PurS PF02700.14 AJZ76572.1 - 3.7e-14 52.6 0.0 4e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase Chordopox_A20R PF05941.13 AJZ76572.1 - 0.047 12.7 0.1 0.052 12.5 0.1 1.0 1 0 0 1 1 1 0 Chordopoxvirus A20R protein ASH PF15780.5 AJZ76573.1 - 9.4e-05 22.6 0.1 0.00013 22.1 0.1 1.2 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PKD PF00801.20 AJZ76573.1 - 0.04 13.8 0.2 0.067 13.0 0.2 1.5 1 1 0 1 1 1 0 PKD domain TMEM51 PF15345.6 AJZ76574.1 - 0.025 14.4 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 TPR_1 PF00515.28 AJZ76575.1 - 2e-25 87.5 3.1 1e-07 31.5 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 AJZ76575.1 - 2.2e-23 80.4 1.9 2e-06 27.5 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 AJZ76575.1 - 6.3e-17 61.0 0.2 3.5e-06 26.6 0.0 4.2 1 1 3 4 4 4 4 TPR repeat TPR_12 PF13424.6 AJZ76575.1 - 2.7e-14 53.2 2.5 1.4e-07 31.7 0.1 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 AJZ76575.1 - 9.8e-14 50.4 4.0 5.2e-05 23.1 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 AJZ76575.1 - 1.7e-13 49.5 0.2 0.0076 16.2 0.0 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 AJZ76575.1 - 1e-12 47.7 0.1 0.011 16.5 0.0 4.6 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 AJZ76575.1 - 5.9e-11 42.8 0.0 2.1e-07 31.4 0.0 3.2 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 AJZ76575.1 - 2.2e-09 37.3 0.0 2.2e-07 30.9 0.0 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 AJZ76575.1 - 9.2e-09 35.7 0.7 7.6e-06 26.3 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 AJZ76575.1 - 2.3e-08 33.9 1.4 0.011 16.1 0.0 3.6 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AJZ76575.1 - 4.1e-07 30.1 0.1 1.6e-06 28.2 0.0 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AJZ76575.1 - 1.5e-06 28.5 2.0 5.2 7.9 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat MIT PF04212.18 AJZ76575.1 - 3.6e-06 26.9 0.4 3.2 7.9 0.0 4.3 4 1 0 4 4 4 2 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 AJZ76575.1 - 1.6e-05 25.0 0.0 0.25 11.4 0.0 3.4 1 1 2 3 3 3 2 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 AJZ76575.1 - 2.9e-05 23.8 0.2 3.3 7.7 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat PPR PF01535.20 AJZ76575.1 - 0.0038 17.4 1.4 7.9 7.0 0.0 4.0 5 0 0 5 5 3 1 PPR repeat SRP_TPR_like PF17004.5 AJZ76575.1 - 0.0062 16.5 0.1 0.15 12.1 0.1 2.3 1 1 0 1 1 1 1 Putative TPR-like repeat 4HB_MCP_1 PF12729.7 AJZ76575.1 - 0.0088 15.6 0.2 0.048 13.2 0.0 2.2 2 1 0 2 2 2 1 Four helix bundle sensory module for signal transduction TOM20_plant PF06552.12 AJZ76575.1 - 0.021 14.6 0.6 5.6 6.7 0.1 3.4 2 2 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_4 PF07721.14 AJZ76575.1 - 0.14 12.9 0.0 4.4 8.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Cas_Csd1 PF09709.10 AJZ76576.1 - 0.051 12.3 0.0 0.051 12.3 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) DnaJ PF00226.31 AJZ76577.1 - 1.5e-24 85.9 1.2 3.6e-24 84.7 1.2 1.7 1 0 0 1 1 1 1 DnaJ domain DUF3258 PF11646.8 AJZ76577.1 - 0.0019 18.3 1.4 0.0032 17.6 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF3258 Protocadherin PF08374.11 AJZ76577.1 - 0.012 15.6 0.1 0.014 15.3 0.1 1.1 1 0 0 1 1 1 0 Protocadherin DUF2615 PF11027.8 AJZ76577.1 - 0.021 14.9 0.1 0.051 13.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) GATase PF00117.28 AJZ76577.1 - 0.038 13.7 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Chordopox_A13L PF05961.11 AJZ76577.1 - 0.2 11.9 1.2 0.49 10.7 0.3 2.1 1 1 1 2 2 2 0 Chordopoxvirus A13L protein Wzt_C PF14524.6 AJZ76579.1 - 0.0011 19.0 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Wzt C-terminal domain PKD PF00801.20 AJZ76579.1 - 0.0015 18.3 0.2 0.0032 17.3 0.2 1.8 1 1 0 1 1 1 1 PKD domain CARDB PF07705.11 AJZ76579.1 - 0.0076 16.5 1.3 0.012 15.9 1.3 1.4 1 1 0 1 1 1 1 CARDB Y_Y_Y PF07495.13 AJZ76579.1 - 0.068 13.1 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Y_Y_Y domain REJ PF02010.15 AJZ76580.1 - 2.3e-13 49.8 1.7 0.0062 15.4 0.0 4.5 1 1 4 5 5 5 3 REJ domain Big_9 PF17963.1 AJZ76580.1 - 2.8e-10 40.8 47.2 0.0042 17.8 0.5 7.2 6 1 1 7 7 7 6 Bacterial Ig domain PKD PF00801.20 AJZ76580.1 - 7.8e-09 35.3 13.5 0.15 11.9 0.1 6.3 6 0 0 6 6 6 4 PKD domain Cadherin_4 PF17803.1 AJZ76580.1 - 0.0011 19.5 45.1 0.2 12.3 1.5 6.9 5 1 0 5 5 5 4 Bacterial cadherin-like domain DUF11 PF01345.18 AJZ76580.1 - 0.02 15.2 4.9 4 7.8 0.1 5.0 3 2 1 4 4 4 0 Domain of unknown function DUF11 Arch_flagellin PF01917.16 AJZ76580.1 - 0.96 9.6 14.5 0.069 13.3 1.7 3.4 3 1 0 3 3 3 0 Archaebacterial flagellin zinc-ribbons_6 PF07191.12 AJZ76581.1 - 0.0094 15.9 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 zinc-ribbons Laminin_EGF PF00053.24 AJZ76581.1 - 0.016 15.3 1.4 0.023 14.9 1.4 1.2 1 0 0 1 1 1 0 Laminin EGF domain Zn-ribbon_8 PF09723.10 AJZ76581.1 - 0.019 15.1 4.8 0.068 13.3 4.8 1.8 1 1 0 1 1 1 0 Zinc ribbon domain zf-NADH-PPase PF09297.11 AJZ76581.1 - 0.032 13.9 2.7 0.075 12.7 0.7 2.0 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain TFIIS_C PF01096.18 AJZ76581.1 - 0.033 14.0 4.1 0.57 10.1 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf_UBZ PF18439.1 AJZ76581.1 - 0.053 13.1 3.0 0.94 9.1 0.2 2.2 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF2628 PF10947.8 AJZ76581.1 - 0.12 12.7 0.7 0.14 12.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) HypA PF01155.19 AJZ76581.1 - 0.14 12.1 1.4 0.19 11.7 1.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-JAB PF14464.6 AJZ76582.1 - 1.4e-10 41.0 0.0 1.7e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RadC PF04002.15 AJZ76582.1 - 0.03 14.3 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 RadC-like JAB domain VKOR PF07884.14 AJZ76583.1 - 0.0027 17.9 0.1 0.0034 17.6 0.1 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family DUF2207 PF09972.9 AJZ76583.1 - 0.015 14.1 0.1 0.017 13.9 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Proteasome PF00227.26 AJZ76585.1 - 1.1e-46 158.8 0.2 1.2e-46 158.6 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Response_reg PF00072.24 AJZ76586.1 - 7.5e-21 74.4 0.5 8.6e-21 74.2 0.5 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF2201 PF09967.9 AJZ76586.1 - 0.02 15.0 0.1 0.096 12.8 0.1 2.0 1 1 1 2 2 2 0 VWA-like domain (DUF2201) Hydrolase_3 PF08282.12 AJZ76587.1 - 2.3e-30 106.2 4.1 5e-22 78.9 1.4 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AJZ76587.1 - 6e-07 29.2 0.1 0.00033 20.2 0.1 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AJZ76587.1 - 1.8e-05 25.1 2.5 0.0035 17.7 0.1 2.9 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AJZ76587.1 - 5.2e-05 23.7 1.1 0.021 15.2 0.0 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AJZ76587.1 - 0.003 17.7 0.1 0.0089 16.1 0.1 1.9 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AJZ76587.1 - 0.13 12.4 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like PHP_C PF13263.6 AJZ76589.1 - 4.6e-11 42.3 0.1 1.8e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 PHP-associated PHP PF02811.19 AJZ76589.1 - 0.0037 17.6 2.9 0.0063 16.8 2.8 1.3 1 1 0 1 1 1 1 PHP domain Glyco_tranf_2_4 PF13704.6 AJZ76589.1 - 0.023 15.2 0.7 0.13 12.8 0.1 2.4 2 1 0 2 2 2 0 Glycosyl transferase family 2 DUF4391 PF14335.6 AJZ76589.1 - 0.029 14.1 0.0 0.049 13.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4391) SMC_N PF02463.19 AJZ76591.1 - 5.6e-65 218.9 0.0 5.7e-64 215.6 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 AJZ76591.1 - 3e-17 63.0 0.2 3.2e-16 59.7 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 AJZ76591.1 - 5.5e-11 43.4 47.2 5.5e-11 43.4 47.2 6.1 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 AJZ76591.1 - 4.1e-09 36.7 18.0 0.00039 20.3 7.8 3.9 2 2 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AJZ76591.1 - 2.3e-06 27.6 28.8 2.3e-06 27.6 28.8 4.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AJZ76591.1 - 5.3e-06 26.1 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AJZ76591.1 - 0.05 14.0 0.0 0.05 14.0 0.0 3.8 3 2 0 3 3 3 0 AAA ATPase domain SbcCD_C PF13558.6 AJZ76591.1 - 0.083 13.1 0.0 0.67 10.2 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF1231 PF06802.11 AJZ76591.1 - 0.087 11.9 0.1 0.19 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1231) APG6_N PF17675.1 AJZ76591.1 - 2.2 8.8 96.9 0.24 11.9 9.2 7.9 3 2 5 8 8 8 0 Apg6 coiled-coil region Alba PF01918.21 AJZ76593.1 - 1e-09 38.0 0.2 1.5e-09 37.6 0.2 1.3 1 0 0 1 1 1 1 Alba Peripla_BP_2 PF01497.18 AJZ76594.1 - 2.1e-22 79.9 0.0 2.5e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Fis1_TPR_N PF14852.6 AJZ76594.1 - 0.11 12.2 0.0 0.85 9.4 0.0 2.1 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat MFS_1 PF07690.16 AJZ76595.1 - 2.3e-26 92.6 73.5 5.9e-20 71.5 36.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AJZ76595.1 - 2.5e-07 29.9 31.7 1.2e-06 27.7 31.7 1.8 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 AJZ76595.1 - 0.00072 18.1 0.4 0.00072 18.1 0.4 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector zf-C2H2_2 PF12756.7 AJZ76595.1 - 0.1 12.9 0.5 0.18 12.1 0.5 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Rota_VP4_MID PF17477.2 AJZ76596.1 - 0.0091 15.4 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Rotavirus VP4 membrane interaction domain DAO PF01266.24 AJZ76597.1 - 1.1e-14 54.8 0.2 1.3e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AJZ76597.1 - 1.6e-13 50.6 0.1 7.8e-13 48.4 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AJZ76597.1 - 1.3e-12 47.8 0.8 3.3e-12 46.5 0.8 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AJZ76597.1 - 1.2e-10 40.7 0.0 3.6e-08 32.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 AJZ76597.1 - 2.9e-10 39.8 0.4 8.8e-09 35.0 0.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AJZ76597.1 - 7e-09 35.0 0.0 0.0029 16.5 0.0 2.3 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 AJZ76597.1 - 1.5e-08 34.2 0.6 2.5e-08 33.5 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AJZ76597.1 - 4.1e-08 32.7 0.0 7e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 AJZ76597.1 - 3.2e-07 29.8 0.3 4.9e-07 29.2 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 AJZ76597.1 - 1.3e-05 25.7 0.2 0.0086 16.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AJZ76597.1 - 4.1e-05 23.7 0.1 9e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 AJZ76597.1 - 0.00015 21.1 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AJZ76597.1 - 0.00045 19.5 0.4 0.00084 18.6 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 AJZ76597.1 - 0.00073 18.9 0.2 0.0026 17.1 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AJZ76597.1 - 0.01 15.7 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 AJZ76597.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Succ_CoA_lig PF13607.6 AJZ76597.1 - 0.06 13.1 0.1 0.57 10.0 0.1 2.3 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain NAD_binding_2 PF03446.15 AJZ76597.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CRPV_capsid PF08762.10 AJZ76597.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 CRPV capsid protein like DUF4363 PF14276.6 AJZ76598.1 - 2.1e-07 31.0 15.9 0.04 14.0 0.1 6.1 5 1 1 6 6 6 4 Domain of unknown function (DUF4363) DUF349 PF03993.12 AJZ76598.1 - 0.087 13.1 1.1 1.2 9.5 0.1 3.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) FlgD_ig PF13860.6 AJZ76598.1 - 0.091 12.6 0.0 4.2 7.3 0.0 2.7 2 0 0 2 2 2 0 FlgD Ig-like domain Cytochrom_B562 PF07361.11 AJZ76598.1 - 4.1 8.1 11.0 62 4.3 0.0 5.6 5 1 1 6 6 6 0 Cytochrome b562 Ribo_biogen_C PF04034.13 AJZ76599.1 - 2.2e-36 124.4 0.0 2.8e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 AJZ76599.1 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI zinc_ribbon_2 PF13240.6 AJZ76600.1 - 0.035 13.8 4.7 0.28 11.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AJZ76600.1 - 0.43 10.1 4.6 3.7 7.1 0.1 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding YhfH PF14149.6 AJZ76600.1 - 0.72 9.9 4.9 2.1 8.4 4.9 1.7 1 1 0 1 1 1 0 YhfH-like protein zinc_ribbon_9 PF14369.6 AJZ76600.1 - 1.1 9.6 4.8 7.3 6.9 0.9 2.1 1 1 1 2 2 2 0 zinc-ribbon zf-ribbon_3 PF13248.6 AJZ76600.1 - 2.2 7.8 7.6 16 5.0 7.6 2.0 1 1 0 1 1 1 0 zinc-ribbon domain Radical_SAM PF04055.21 AJZ76601.1 - 1e-18 68.3 0.1 1.8e-18 67.5 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily ABC_tran_CTD PF16326.5 AJZ76603.1 - 0.076 13.3 0.2 0.076 13.3 0.2 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain Cauli_VI PF01693.16 AJZ76603.1 - 0.2 12.0 1.6 4.2 7.8 0.3 2.4 2 0 0 2 2 2 0 Caulimovirus viroplasmin PAT1 PF09770.9 AJZ76603.1 - 0.32 9.2 3.7 11 4.1 0.0 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF3408 PF11888.8 AJZ76603.1 - 0.97 9.6 4.7 0.26 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) M PF02370.16 AJZ76603.1 - 1.7 9.5 7.6 0.13 12.9 2.5 2.0 2 0 0 2 2 2 0 M protein repeat DnaJ_CXXCXGXG PF00684.19 AJZ76604.1 - 0.0011 19.2 12.7 0.0032 17.8 12.4 1.9 1 1 0 1 1 1 1 DnaJ central domain DUF5351 PF17302.2 AJZ76604.1 - 0.022 14.9 11.8 0.23 11.7 0.6 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5351) Lar_restr_allev PF14354.6 AJZ76604.1 - 0.027 14.8 16.1 0.35 11.3 1.6 3.1 2 1 1 3 3 3 0 Restriction alleviation protein Lar Anti-TRAP PF15777.5 AJZ76604.1 - 0.11 12.5 14.0 0.11 12.5 0.4 2.9 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Prim_Zn_Ribbon PF08273.12 AJZ76604.1 - 0.32 11.3 15.1 3.2 8.1 0.6 3.3 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-nanos PF05741.13 AJZ76604.1 - 0.33 11.2 13.4 1.5 9.1 8.8 2.8 2 1 1 3 3 3 0 Nanos RNA binding domain YacG PF03884.14 AJZ76604.1 - 0.36 10.6 11.6 1.2 8.9 2.7 2.7 2 1 1 3 3 3 0 DNA gyrase inhibitor YacG Zn_Tnp_IS1595 PF12760.7 AJZ76604.1 - 0.38 10.8 15.7 0.7 9.9 3.6 3.1 1 1 2 3 3 3 0 Transposase zinc-ribbon domain zf-Di19 PF05605.12 AJZ76604.1 - 0.64 10.4 16.1 9.3 6.6 0.1 2.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_CopZ PF18423.1 AJZ76604.1 - 1 9.4 14.6 3.8 7.5 0.5 3.2 3 0 0 3 3 3 0 Zinc binding domain Zn-C2H2_12 PF18112.1 AJZ76604.1 - 1.6 9.3 13.9 1.3 9.5 1.7 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Rad50_zn_hook PF04423.14 AJZ76604.1 - 1.6 8.6 11.9 3.9 7.4 0.7 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif TF_Zn_Ribbon PF08271.12 AJZ76604.1 - 2.8 7.5 13.1 6 6.5 0.3 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 AJZ76604.1 - 4.7 7.5 13.3 12 6.2 1.8 3.3 2 2 2 4 4 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Prok-RING_4 PF14447.6 AJZ76604.1 - 5.4 7.0 18.0 7.4 6.5 4.4 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Nop10p PF04135.12 AJZ76604.1 - 6.3 6.9 6.8 15 5.8 0.4 2.9 3 0 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family DNA_ligase_ZBD PF03119.16 AJZ76604.1 - 6.6 6.8 15.7 5.7 7.0 2.8 3.3 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Aminotran_1_2 PF00155.21 AJZ76605.1 - 8e-57 193.0 0.0 1.1e-56 192.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CM_2 PF01817.21 AJZ76605.1 - 4.9e-12 46.0 0.5 2.1e-11 44.0 0.6 2.0 2 0 0 2 2 2 1 Chorismate mutase type II Aminotran_5 PF00266.19 AJZ76605.1 - 8.6e-07 28.2 0.0 1.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AJZ76605.1 - 5.3e-05 21.9 0.0 9.4e-05 21.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 AJZ76605.1 - 8.2e-05 21.6 0.6 0.00093 18.2 0.2 2.5 3 0 0 3 3 3 1 Allinase DegT_DnrJ_EryC1 PF01041.17 AJZ76605.1 - 0.00036 20.0 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family LppX_LprAFG PF07161.13 AJZ76605.1 - 0.00053 19.9 0.1 0.0012 18.8 0.0 1.5 2 0 0 2 2 2 1 LppX_LprAFG lipoprotein Beta_elim_lyase PF01212.21 AJZ76605.1 - 0.00068 19.0 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Leuk-A4-hydro_C PF09127.11 AJZ76605.1 - 0.076 13.1 0.6 0.54 10.4 0.0 2.4 2 1 1 3 3 3 0 Leukotriene A4 hydrolase, C-terminal DUF4921 PF16268.5 AJZ76606.1 - 3.8e-09 35.9 0.2 1.1e-07 31.1 0.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4921) GalP_UDP_transf PF01087.22 AJZ76606.1 - 1.5e-08 35.3 2.3 1.3e-07 32.2 0.8 2.4 2 1 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.23 AJZ76606.1 - 4.5e-08 33.7 0.0 0.003 18.3 0.0 2.3 2 0 0 2 2 2 2 HIT domain DUF4931 PF16285.5 AJZ76606.1 - 0.00077 18.8 1.3 0.017 14.4 0.1 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4931) GalP_UDP_tr_C PF02744.17 AJZ76606.1 - 0.0026 17.5 0.0 0.0079 15.9 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.8 AJZ76606.1 - 0.0039 17.7 0.0 0.028 14.9 0.0 2.1 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding zf-Di19 PF05605.12 AJZ76606.1 - 0.0085 16.4 0.1 2.7 8.3 0.0 2.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 AJZ76606.1 - 0.27 11.1 1.6 16 5.5 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PhosphMutase PF10143.9 AJZ76607.1 - 1.9e-41 141.7 0.0 2.8e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 AJZ76607.1 - 6.5e-28 97.8 0.1 8e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 AJZ76607.1 - 0.0024 17.5 0.0 0.0047 16.5 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 AJZ76607.1 - 0.093 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Alkaline phosphatase Pico_P1A PF02226.16 AJZ76608.1 - 0.15 12.1 1.9 0.36 10.9 0.1 2.5 2 1 1 3 3 3 0 Picornavirus coat protein (VP4) Gar1 PF04410.14 AJZ76609.1 - 2.9e-06 27.1 0.0 3.1e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region TPR_1 PF00515.28 AJZ76610.1 - 4.4e-19 67.4 6.2 5.2e-06 26.0 0.0 5.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 AJZ76610.1 - 2.4e-14 52.2 0.4 0.029 14.4 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 AJZ76610.1 - 7.3e-12 44.8 4.0 0.0044 17.3 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 AJZ76610.1 - 1.8e-11 44.4 0.1 0.00052 20.5 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AJZ76610.1 - 2.2e-11 43.8 1.5 0.00011 22.5 0.1 4.5 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 AJZ76610.1 - 9.9e-11 41.5 0.0 0.56 11.2 0.0 5.8 1 1 5 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 AJZ76610.1 - 4.9e-10 38.8 2.5 0.0099 16.0 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 AJZ76610.1 - 1.5e-09 37.2 2.5 0.65 10.2 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat DUF3856 PF12968.7 AJZ76610.1 - 6e-06 26.4 0.2 3.7 7.6 0.0 4.6 1 1 2 4 4 4 2 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 AJZ76610.1 - 9.2e-06 25.8 0.7 0.012 15.8 0.1 3.1 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4919 PF16266.5 AJZ76610.1 - 9.4e-06 25.7 0.1 0.001 19.1 0.0 2.7 1 1 2 3 3 3 1 Domain of unknown function (DUF4919) BTAD PF03704.17 AJZ76610.1 - 1.7e-05 25.3 0.0 0.0042 17.5 0.0 2.9 1 1 2 3 3 3 2 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 AJZ76610.1 - 0.00011 22.2 0.4 0.1 12.7 0.0 4.1 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 AJZ76610.1 - 0.00016 22.2 0.1 0.52 11.0 0.0 3.2 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 AJZ76610.1 - 0.00017 21.4 1.7 2.2 8.3 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 AJZ76610.1 - 0.00052 19.6 0.1 0.017 14.8 0.0 3.0 3 0 0 3 3 3 1 TPR repeat Coatomer_E PF04733.14 AJZ76610.1 - 0.00072 19.1 0.5 0.43 9.9 0.0 2.3 1 1 0 2 2 2 2 Coatomer epsilon subunit TPR_6 PF13174.6 AJZ76610.1 - 0.0043 17.6 0.1 31 5.5 0.0 5.1 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 AJZ76610.1 - 0.012 15.8 0.0 1.8 8.8 0.0 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat ImpA_N PF06812.12 AJZ76610.1 - 0.054 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system NAD_binding_7 PF13241.6 AJZ76612.1 - 4e-19 69.0 0.2 9.9e-19 67.7 0.1 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 AJZ76612.1 - 5.2e-07 29.0 0.1 1.1e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 AJZ76612.1 - 2.4e-05 24.4 0.7 3.4e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 AJZ76612.1 - 0.0035 17.6 0.2 0.0087 16.3 0.2 1.7 1 1 0 1 1 1 1 TrkA-N domain CysG_dimeriser PF10414.9 AJZ76612.1 - 0.0053 16.4 0.0 0.0096 15.6 0.0 1.4 1 0 0 1 1 1 1 Sirohaem synthase dimerisation region KH_2 PF07650.17 AJZ76612.1 - 0.2 11.5 3.7 1.1 9.2 0.5 2.8 2 1 0 2 2 2 0 KH domain HD PF01966.22 AJZ76613.1 - 9.4e-16 58.1 0.4 1.6e-15 57.4 0.4 1.4 1 0 0 1 1 1 1 HD domain REPA_OB_2 PF16900.5 AJZ76614.1 - 2.9e-05 23.9 0.1 3.1e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 AJZ76614.1 - 0.0013 18.7 0.2 0.0018 18.2 0.2 1.3 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain PGK PF00162.19 AJZ76615.1 - 2.5e-98 329.5 0.5 2.9e-98 329.3 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PRC PF05239.16 AJZ76616.1 - 1.4e-11 44.3 0.6 7.5e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 PRC-barrel domain DUF2171 PF09939.9 AJZ76616.1 - 6.5e-07 29.5 2.7 0.02 15.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2171) GTP_EFTU_D4 PF14578.6 AJZ76616.1 - 0.061 13.2 0.2 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 DUF4891 PF16232.5 AJZ76617.1 - 0.27 11.8 2.1 0.46 11.0 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4891) Ribosomal_L16 PF00252.18 AJZ76619.1 - 2.2e-29 102.1 1.0 2.7e-29 101.8 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rhodanese PF00581.20 AJZ76620.1 - 1.1e-37 128.9 0.1 1.2e-19 70.8 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Ribosomal_L18 PF17135.4 AJZ76621.1 - 8.3e-09 35.1 0.1 8.9e-09 35.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 AJZ76621.1 - 5.3e-07 30.4 1.2 7e-07 30.0 1.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Aconitase PF00330.20 AJZ76622.1 - 7.1e-94 315.4 2.7 8.6e-92 308.5 2.7 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) FYRC PF05965.14 AJZ76623.1 - 0.045 13.9 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 F/Y rich C-terminus DAO PF01266.24 AJZ76624.1 - 4.2e-44 151.6 0.0 5.5e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 AJZ76624.1 - 5.2e-11 41.8 0.0 2.7e-05 23.0 0.0 2.5 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 AJZ76624.1 - 2.1e-05 23.9 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AJZ76624.1 - 0.0003 21.0 0.0 0.00076 19.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AJZ76624.1 - 0.00053 18.8 0.1 0.11 11.1 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein Trp_halogenase PF04820.14 AJZ76624.1 - 0.055 12.3 0.3 0.91 8.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 AJZ76624.1 - 0.1 12.2 0.1 0.73 9.5 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 AJZ76624.1 - 0.14 11.4 0.0 9.9 5.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain PFK PF00365.20 AJZ76624.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase Pyr_redox PF00070.27 AJZ76624.1 - 0.18 12.4 0.4 4 8.1 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase OTCace_N PF02729.21 AJZ76625.1 - 1.3e-52 177.8 0.1 1.9e-52 177.2 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AJZ76625.1 - 4e-49 166.7 0.0 7.4e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Prefoldin PF02996.17 AJZ76626.1 - 5.5e-18 65.0 1.8 8.8e-18 64.4 1.8 1.3 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 AJZ76626.1 - 1.1e-05 25.3 0.6 1.1e-05 25.3 0.6 1.8 2 0 0 2 2 2 1 Prefoldin subunit Nif11 PF07862.11 AJZ76626.1 - 0.01 16.1 1.4 0.023 15.0 1.4 1.7 1 0 0 1 1 1 0 Nif11 domain BST2 PF16716.5 AJZ76626.1 - 0.018 15.6 0.8 0.018 15.6 0.8 2.0 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 ABC_tran_CTD PF16326.5 AJZ76626.1 - 0.032 14.5 2.0 0.088 13.1 2.0 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain CRR7 PF12095.8 AJZ76626.1 - 0.068 13.6 1.1 12 6.4 0.2 2.2 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF2524 PF10732.9 AJZ76626.1 - 0.11 12.8 7.7 0.088 13.1 2.8 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF2524) Mod_r PF07200.13 AJZ76626.1 - 0.27 11.3 9.3 2.8 8.1 9.3 2.0 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Sipho_Gp157 PF05565.11 AJZ76626.1 - 0.39 10.7 5.4 5.4 7.0 1.8 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 TSNAXIP1_N PF15739.5 AJZ76626.1 - 1.4 9.3 7.7 0.37 11.2 2.7 2.0 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus PEPCK_ATP PF01293.20 AJZ76627.1 - 2.1e-214 712.5 0.0 2.4e-214 712.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 AJZ76627.1 - 0.029 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Spt5-NGN PF03439.13 AJZ76628.1 - 2.4e-21 75.4 0.0 3.7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 AJZ76628.1 - 8.9e-07 28.7 0.1 1.9e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 KOW motif Glyco_hydro_20b PF02838.15 AJZ76628.1 - 0.052 14.3 0.2 0.17 12.6 0.1 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 20, domain 2 AsnC_trans_reg PF01037.21 AJZ76629.1 - 5.2e-13 48.8 0.1 7.9e-13 48.2 0.1 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AJZ76629.1 - 1.8e-09 37.0 0.3 3.5e-09 36.1 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AJZ76629.1 - 6.8e-08 32.2 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain B-block_TFIIIC PF04182.12 AJZ76629.1 - 0.00045 20.3 0.4 0.00057 20.0 0.4 1.4 1 1 0 1 1 1 1 B-block binding subunit of TFIIIC MarR PF01047.22 AJZ76629.1 - 0.00058 19.7 0.1 0.0013 18.6 0.1 1.6 1 0 0 1 1 1 1 MarR family Ribosomal_S25 PF03297.15 AJZ76629.1 - 0.006 16.8 0.5 0.12 12.6 0.1 2.1 2 0 0 2 2 2 1 S25 ribosomal protein MarR_2 PF12802.7 AJZ76629.1 - 0.014 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 AJZ76629.1 - 0.022 14.7 0.5 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 HTH domain Mga PF05043.13 AJZ76629.1 - 0.043 14.4 0.1 0.094 13.3 0.1 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain Rrf2 PF02082.20 AJZ76629.1 - 0.057 13.8 0.1 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator HTH_psq PF05225.16 AJZ76629.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_34 PF13601.6 AJZ76629.1 - 0.074 13.2 0.4 2.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain UPF0126 PF03458.13 AJZ76630.1 - 3e-36 123.1 22.3 1e-18 67.0 8.3 2.7 2 1 1 3 3 3 2 UPF0126 domain RNA_pol_Rpb5_C PF01191.19 AJZ76631.1 - 1.2e-25 89.2 0.1 1.6e-25 88.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain MG2 PF01835.19 AJZ76632.1 - 0.013 16.0 0.1 0.024 15.1 0.1 1.5 1 0 0 1 1 1 0 MG2 domain FlgD_ig PF13860.6 AJZ76632.1 - 0.017 15.0 0.5 0.39 10.6 0.1 2.5 2 0 0 2 2 2 0 FlgD Ig-like domain Glucodextran_C PF09985.9 AJZ76633.1 - 0.046 13.2 0.1 0.46 9.9 0.0 2.3 2 1 1 3 3 3 0 C-terminal binding-module, SLH-like, of glucodextranase MG2 PF01835.19 AJZ76633.1 - 0.07 13.6 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 MG2 domain CBM_35 PF16990.5 AJZ76634.1 - 0.071 13.4 0.2 0.61 10.4 0.3 2.4 2 1 0 2 2 2 0 Carbohydrate binding module (family 35) DUF111 PF01969.17 AJZ76635.1 - 8e-106 354.3 2.1 9e-106 354.1 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 EB PF01683.18 AJZ76636.1 - 0.032 14.5 4.0 1.9 8.8 0.2 2.6 2 1 0 2 2 2 0 EB module CBM_14 PF01607.24 AJZ76636.1 - 1.6 9.0 3.6 0.58 10.4 0.6 1.9 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain CC PF04942.14 AJZ76636.1 - 1.9 8.8 7.2 5.9 7.2 1.1 3.2 3 0 0 3 3 3 0 CC domain ZT_dimer PF16916.5 AJZ76637.1 - 8.3e-47 157.2 18.8 5.2e-18 64.9 5.8 3.2 3 0 0 3 3 3 3 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 AJZ76637.1 - 1.3e-40 139.3 18.4 2.2e-40 138.5 18.4 1.4 1 0 0 1 1 1 1 Cation efflux family ATP-synt_I PF03899.15 AJZ76637.1 - 0.13 12.7 0.4 0.13 12.7 0.4 2.6 3 0 0 3 3 3 0 ATP synthase I chain BON PF04972.17 AJZ76637.1 - 0.38 11.1 2.4 3.8 7.9 0.0 3.4 4 0 0 4 4 4 0 BON domain Cu-oxidase_3 PF07732.15 AJZ76638.1 - 2.1e-24 85.8 7.7 3.5e-20 72.2 0.7 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 AJZ76638.1 - 3.6e-22 78.6 8.8 1.7e-10 40.7 1.2 3.3 3 0 0 3 3 3 3 Multicopper oxidase RNA_pol_N PF01194.17 AJZ76639.1 - 1.2e-28 99.1 1.0 1.6e-28 98.8 1.0 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 AJZ76639.1 - 0.03 14.6 1.0 0.056 13.7 1.0 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) ADH_N PF08240.12 AJZ76640.1 - 1.2e-24 86.3 1.6 1.8e-24 85.7 1.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 AJZ76640.1 - 5.8e-12 45.5 0.1 1.8e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 AJZ76640.1 - 5.5e-08 32.8 0.0 3e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 AJZ76640.1 - 0.00018 21.6 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N_2 PF13602.6 AJZ76640.1 - 0.078 14.0 0.0 0.21 12.6 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase MAF_flag10 PF01973.18 AJZ76642.1 - 1.3e-38 132.4 0.7 1.8e-38 131.9 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF115 TPK_catalytic PF04263.16 AJZ76642.1 - 0.034 14.2 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain GATase PF00117.28 AJZ76643.1 - 3e-44 151.1 0.0 4.7e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 AJZ76643.1 - 2e-34 117.5 0.1 4.8e-34 116.3 0.1 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 AJZ76643.1 - 3.3e-11 42.8 0.1 5.7e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 AJZ76643.1 - 2.2e-08 34.1 0.0 7e-08 32.5 0.1 1.8 2 1 0 2 2 2 1 Peptidase C26 ThiI PF02568.14 AJZ76643.1 - 2.5e-05 24.0 0.0 0.00015 21.4 0.0 2.0 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 AJZ76643.1 - 0.00052 18.9 0.0 0.005 15.7 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 AJZ76643.1 - 0.0048 16.4 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 AJZ76643.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Adenine_deam_C PF13382.6 AJZ76644.1 - 6.9e-46 155.7 0.0 1.3e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 AJZ76644.1 - 3e-15 56.4 0.0 8.4e-15 54.9 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AJZ76644.1 - 4.4e-09 36.3 0.1 7.6e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family CobS PF02654.15 AJZ76645.1 - 1.1e-43 149.8 15.4 1.3e-43 149.6 15.4 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase DUF1461 PF07314.11 AJZ76645.1 - 0.0045 16.9 0.9 0.02 14.8 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1461) Aldedh PF00171.22 AJZ76646.1 - 1e-141 472.6 0.1 1.2e-141 472.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family partial_CstF PF15861.5 AJZ76648.1 - 0.054 13.3 2.2 0.07 12.9 0.6 2.0 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain DUF3150 PF11348.8 AJZ76648.1 - 0.056 12.7 1.1 0.2 10.9 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3150) FlgN PF05130.12 AJZ76648.1 - 0.36 11.3 5.3 4.7 7.7 0.3 2.2 1 1 1 2 2 2 0 FlgN protein DUF720 PF05302.11 AJZ76648.1 - 0.59 10.0 13.8 3.4 7.5 4.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF720) HxlR PF01638.17 AJZ76649.1 - 1.6e-24 85.5 0.2 3.9e-24 84.3 0.0 1.6 2 0 0 2 2 2 1 HxlR-like helix-turn-helix PadR PF03551.14 AJZ76649.1 - 0.0022 17.9 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 AJZ76649.1 - 0.042 13.8 0.5 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 MarR family HTH_34 PF13601.6 AJZ76649.1 - 0.053 13.7 0.0 0.1 12.8 0.0 1.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_12 PF08461.10 AJZ76649.1 - 0.092 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain CBS PF00571.28 AJZ76650.1 - 0.00024 21.5 4.4 0.6 10.6 0.1 3.8 4 1 1 5 5 5 2 CBS domain HTH_20 PF12840.7 AJZ76651.1 - 0.0043 17.1 0.0 0.006 16.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain DUF742 PF05331.11 AJZ76651.1 - 0.0083 15.9 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF742) FUR PF01475.19 AJZ76651.1 - 0.013 15.7 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_IclR PF09339.10 AJZ76651.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain TrmB PF01978.19 AJZ76651.1 - 0.019 14.8 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB CBS PF00571.28 AJZ76652.1 - 3.9e-50 168.1 12.9 6.8e-14 52.1 0.2 4.1 4 0 0 4 4 4 4 CBS domain Toxin_15 PF07906.13 AJZ76652.1 - 0.076 12.6 0.9 0.1 12.1 0.9 1.2 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region Usp PF00582.26 AJZ76653.1 - 7.8e-33 114.0 0.0 8.8e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Mrr_cat PF04471.12 AJZ76654.1 - 8.9e-06 25.7 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease DUF4143 PF13635.6 AJZ76654.1 - 0.0063 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4143) HTH_5 PF01022.20 AJZ76655.1 - 2.6e-07 30.4 0.0 3.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_12 PF08461.10 AJZ76655.1 - 0.00011 22.0 0.1 0.00022 21.1 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_20 PF12840.7 AJZ76655.1 - 0.018 15.1 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 AJZ76655.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain PUA PF01472.20 AJZ76656.1 - 3.7e-12 46.0 0.4 5.4e-12 45.5 0.4 1.3 1 0 0 1 1 1 1 PUA domain TGT_C2 PF14810.6 AJZ76656.1 - 5e-08 33.0 0.0 8.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Patch-forming domain C2 of tRNA-guanine transglycosylase Trm56 PF01994.16 AJZ76657.1 - 5.3e-49 165.1 0.3 7.2e-49 164.7 0.3 1.2 1 0 0 1 1 1 1 tRNA ribose 2'-O-methyltransferase, aTrm56 SpoU_methylase PF00588.19 AJZ76657.1 - 4.8e-06 26.8 0.0 6.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family TFIIE_alpha PF02002.17 AJZ76658.1 - 5.4e-16 58.3 1.0 5.4e-16 58.3 1.0 1.9 2 0 0 2 2 2 1 TFIIE alpha subunit D5_N PF08706.11 AJZ76658.1 - 0.0017 18.6 0.2 0.0022 18.3 0.2 1.1 1 0 0 1 1 1 1 D5 N terminal like TrmB PF01978.19 AJZ76658.1 - 0.034 14.0 0.0 0.07 13.0 0.0 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sigma70_r3 PF04539.16 AJZ76658.1 - 0.04 14.0 1.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-70 region 3 Mu-like_Com PF10122.9 AJZ76658.1 - 0.14 11.6 1.8 0.14 11.6 0.4 1.7 2 0 0 2 2 2 0 Mu-like prophage protein Com zf_CopZ PF18423.1 AJZ76658.1 - 0.31 11.0 5.1 0.61 10.1 0.5 2.3 1 1 1 2 2 2 0 Zinc binding domain Lum_binding PF00677.17 AJZ76659.1 - 6e-45 151.2 6.7 5.2e-24 84.0 0.2 2.0 2 0 0 2 2 2 2 Lumazine binding domain DUF3159 PF11361.8 AJZ76660.1 - 0.02 14.7 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) Pro_dh PF01619.18 AJZ76661.1 - 1.1e-28 100.7 0.1 1.6e-28 100.1 0.1 1.2 1 0 0 1 1 1 1 Proline dehydrogenase NRDD PF13597.6 AJZ76662.1 - 8.3e-27 94.2 0.0 4.7e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Anaerobic ribonucleoside-triphosphate reductase HTH_20 PF12840.7 AJZ76662.1 - 5.8e-10 39.1 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain ATP-cone PF03477.16 AJZ76662.1 - 9.4e-07 29.3 1.3 1.1e-05 25.9 0.0 3.2 3 0 0 3 3 3 1 ATP cone domain Lig_C PF18330.1 AJZ76662.1 - 0.0023 17.9 0.5 0.15 12.0 0.0 3.2 3 0 0 3 3 3 1 Ligase Pab1020 C-terminal region Rubredoxin_2 PF18073.1 AJZ76662.1 - 0.0077 15.9 1.2 0.012 15.3 1.2 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain TackOD1 PF18551.1 AJZ76662.1 - 0.081 12.6 0.3 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zf-ribbon_3 PF13248.6 AJZ76662.1 - 0.28 10.7 4.1 2.2 7.8 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain ABC-3 PF00950.17 AJZ76664.1 - 4.5e-65 219.7 33.8 5.1e-65 219.5 33.8 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AJZ76664.1 - 3.5e-08 32.8 33.3 7.2e-08 31.8 33.3 1.6 1 1 0 1 1 1 1 FecCD transport family CD20 PF04103.15 AJZ76664.1 - 0.0068 16.5 6.5 0.0068 16.5 6.5 3.0 2 2 2 4 4 4 1 CD20-like family ZnuA PF01297.17 AJZ76665.1 - 6.5e-74 248.6 0.1 7.4e-74 248.4 0.1 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic CheD PF03975.13 AJZ76666.1 - 7.7e-31 106.4 0.0 1.1e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 CheD chemotactic sensory transduction Cu-oxidase_4 PF02578.15 AJZ76666.1 - 0.045 13.4 0.2 0.093 12.3 0.2 1.4 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase CheC PF04509.12 AJZ76667.1 - 2.6e-11 43.2 0.8 6e-11 42.1 0.0 2.0 3 0 0 3 3 3 1 CheC-like family CheX PF13690.6 AJZ76667.1 - 2.8e-07 30.6 0.1 1e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Chemotaxis phosphatase CheX Fer2_3 PF13085.6 AJZ76667.1 - 0.024 14.6 0.1 0.048 13.7 0.1 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF5512 PF17631.2 AJZ76667.1 - 0.085 12.9 0.1 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5512) CheB_methylest PF01339.17 AJZ76668.1 - 3.4e-56 189.6 1.0 1.9e-55 187.2 0.5 2.1 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 AJZ76668.1 - 1.4e-16 60.6 0.5 3.9e-16 59.2 0.5 1.7 1 0 0 1 1 1 1 Response regulator receiver domain TrmB PF01978.19 AJZ76670.1 - 3.9e-15 55.5 0.0 2.4e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 AJZ76670.1 - 8.3e-05 22.4 0.1 0.0025 17.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AJZ76670.1 - 0.007 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 MarR family Regulator_TrmB PF11495.8 AJZ76670.1 - 0.0076 15.5 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_20 PF12840.7 AJZ76670.1 - 0.04 14.0 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Rrf2 PF02082.20 AJZ76670.1 - 0.041 14.2 0.1 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator HTH_IclR PF09339.10 AJZ76670.1 - 0.11 12.3 0.2 0.3 10.9 0.1 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain Peptidase_M10 PF00413.24 AJZ76671.1 - 6.4e-10 39.1 0.2 6.9e-09 35.7 0.1 2.0 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 AJZ76671.1 - 0.00042 20.0 0.1 0.0006 19.5 0.1 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.9 AJZ76671.1 - 0.0006 18.9 0.1 0.0016 17.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase M66 Peptidase_M43 PF05572.13 AJZ76671.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 AJZ76671.1 - 0.046 14.2 0.1 0.073 13.6 0.1 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M48 PF01435.18 AJZ76671.1 - 0.065 13.0 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 DUF4953 PF16313.5 AJZ76671.1 - 0.088 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 AJZ76671.1 - 0.17 11.5 1.3 0.64 9.6 1.1 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like AA_kinase PF00696.28 AJZ76673.1 - 1.7e-29 103.1 0.4 2.9e-29 102.4 0.4 1.4 1 1 0 1 1 1 1 Amino acid kinase family Phage_holin_3_3 PF16083.5 AJZ76674.1 - 0.023 14.8 0.1 0.032 14.3 0.1 1.3 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III DUF2407_C PF13373.6 AJZ76674.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain ABC_tran PF00005.27 AJZ76675.1 - 1.6e-18 67.6 0.1 2.2e-18 67.1 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AviRa PF11599.8 AJZ76675.1 - 0.0042 16.6 0.3 0.0056 16.2 0.3 1.1 1 0 0 1 1 1 1 RRNA methyltransferase AviRa AAA_13 PF13166.6 AJZ76675.1 - 0.018 13.7 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AJZ76675.1 - 0.058 13.6 0.1 4.1 7.7 0.1 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SHOCT PF09851.9 AJZ76676.1 - 0.006 16.3 0.4 0.014 15.1 0.4 1.7 1 0 0 1 1 1 1 Short C-terminal domain adh_short_C2 PF13561.6 AJZ76676.1 - 0.032 13.8 0.1 0.049 13.2 0.1 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF1840 PF08895.11 AJZ76676.1 - 0.21 11.9 3.5 0.41 11.0 3.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) MethyltransfD12 PF02086.15 AJZ76677.1 - 4.2e-26 92.2 0.2 5e-26 91.9 0.2 1.1 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Na_H_Exchanger PF00999.21 AJZ76678.1 - 1.8e-59 201.5 49.8 2.2e-59 201.2 49.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Spore_YabQ PF09578.10 AJZ76678.1 - 0.085 13.1 0.1 0.085 13.1 0.1 3.9 5 1 0 5 5 5 0 Spore cortex protein YabQ (Spore_YabQ) ATP1G1_PLM_MAT8 PF02038.16 AJZ76678.1 - 1.4 8.4 7.0 12 5.4 0.9 4.1 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family TPR_1 PF00515.28 AJZ76679.1 - 2e-22 78.0 1.2 9.4e-09 34.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AJZ76679.1 - 2.5e-19 67.7 0.3 3.1e-05 23.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 AJZ76679.1 - 3e-13 48.9 0.4 2.7e-05 24.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AJZ76679.1 - 5.2e-13 48.5 3.5 4e-06 26.4 0.2 3.4 1 1 2 3 3 3 3 TPR repeat TPR_7 PF13176.6 AJZ76679.1 - 1.5e-10 40.4 0.0 0.012 15.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AJZ76679.1 - 1.7e-10 41.3 0.0 3.8e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 AJZ76679.1 - 2.3e-10 40.6 0.2 4e-05 23.8 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 AJZ76679.1 - 6.5e-10 38.7 5.8 0.0005 20.3 0.0 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AJZ76679.1 - 1.1e-09 38.6 0.4 3.6e-06 27.4 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AJZ76679.1 - 2.2e-09 37.4 0.0 0.063 14.1 0.0 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat MG2 PF01835.19 AJZ76679.1 - 0.00044 20.7 0.1 0.034 14.6 0.0 2.8 2 0 0 2 2 2 1 MG2 domain TPR_10 PF13374.6 AJZ76679.1 - 0.0008 19.2 2.9 0.048 13.6 0.4 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 AJZ76679.1 - 0.00096 19.6 0.2 2.7 8.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 AJZ76679.1 - 0.0036 16.3 0.2 0.15 11.0 0.0 2.0 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 AJZ76679.1 - 0.0057 16.7 0.1 3.9 7.6 0.0 2.8 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 AJZ76679.1 - 0.0084 15.6 0.1 0.12 11.7 0.0 2.0 1 1 1 2 2 2 1 Coatomer epsilon subunit TPR_9 PF13371.6 AJZ76679.1 - 0.0097 16.0 0.0 0.074 13.2 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AJZ76679.1 - 0.019 15.2 0.2 0.034 14.4 0.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 AJZ76679.1 - 0.02 15.0 0.0 2.3 8.3 0.0 2.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) PPR PF01535.20 AJZ76679.1 - 0.053 13.8 0.2 7.9 7.0 0.0 3.1 3 0 0 3 3 3 0 PPR repeat TPR_15 PF13429.6 AJZ76679.1 - 0.11 11.7 0.0 6.6 5.9 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat dCache_1 PF02743.18 AJZ76679.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Cache domain MIT PF04212.18 AJZ76679.1 - 0.18 11.9 1.0 36 4.5 0.0 3.0 1 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain FAP PF07174.11 AJZ76679.1 - 0.32 10.4 20.7 0.59 9.5 20.7 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SARG PF15385.6 AJZ76679.1 - 2.9 7.0 7.7 4.6 6.4 7.7 1.2 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein LEA_2 PF03168.13 AJZ76680.1 - 0.028 14.9 0.1 0.12 12.9 0.0 2.0 1 1 1 2 2 2 0 Late embryogenesis abundant protein Cpn60_TCP1 PF00118.24 AJZ76681.1 - 3.2e-183 609.8 19.1 3.7e-183 609.6 19.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pro_isomerase PF00160.21 AJZ76682.1 - 2.3e-45 154.7 0.2 4.8e-45 153.7 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PsbP PF01789.16 AJZ76682.1 - 0.00012 22.2 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 PsbP Methyltransf_31 PF13847.6 AJZ76683.1 - 1.5e-20 73.6 0.0 1.9e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJZ76683.1 - 1.4e-17 64.2 0.0 2.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJZ76683.1 - 1.1e-16 61.3 0.0 1.9e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AJZ76683.1 - 5.8e-15 55.3 0.1 1.8e-14 53.7 0.1 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AJZ76683.1 - 8.1e-14 51.8 0.0 1.1e-13 51.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJZ76683.1 - 5.1e-12 46.4 0.0 1e-11 45.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AJZ76683.1 - 1.4e-06 28.0 0.2 3.6e-06 26.6 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 AJZ76683.1 - 2.3e-06 27.4 0.0 3.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 AJZ76683.1 - 3.7e-05 23.0 0.0 5.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase CheR PF01739.18 AJZ76683.1 - 6.1e-05 22.6 0.5 0.00031 20.3 0.3 2.0 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain CMAS PF02353.20 AJZ76683.1 - 0.00022 20.6 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.16 AJZ76683.1 - 0.00052 19.2 0.4 0.02 14.0 0.4 2.3 1 1 0 1 1 1 1 mRNA capping enzyme PCMT PF01135.19 AJZ76683.1 - 0.0025 17.6 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 AJZ76683.1 - 0.0028 17.1 0.1 0.0046 16.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 AJZ76683.1 - 0.0087 15.0 0.1 0.02 13.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 AJZ76683.1 - 0.0091 16.1 0.0 0.022 14.9 0.0 1.7 2 1 0 2 2 1 1 FtsJ-like methyltransferase Tail_P2_I PF09684.10 AJZ76683.1 - 0.017 15.0 0.0 0.05 13.5 0.0 1.7 1 1 0 1 1 1 0 Phage tail protein (Tail_P2_I) TehB PF03848.14 AJZ76683.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB GCD14 PF08704.10 AJZ76683.1 - 0.027 14.1 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_5 PF01795.19 AJZ76683.1 - 0.031 13.8 0.6 0.05 13.1 0.0 1.6 2 0 0 2 2 2 0 MraW methylase family Methyltransf_2 PF00891.18 AJZ76683.1 - 0.044 13.1 0.1 0.13 11.5 0.1 1.7 1 1 0 1 1 1 0 O-methyltransferase domain Proteasome PF00227.26 AJZ76684.1 - 1.4e-49 168.1 0.4 1.6e-49 168.0 0.4 1.0 1 0 0 1 1 1 1 Proteasome subunit Fe-ADH_2 PF13685.6 AJZ76685.1 - 5.9e-71 239.1 0.2 7.9e-71 238.7 0.2 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AJZ76685.1 - 1.2e-19 70.4 0.1 5.3e-19 68.3 0.1 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 AJZ76685.1 - 1.9e-05 24.0 0.3 0.00021 20.6 0.3 2.4 1 1 0 1 1 1 1 3-dehydroquinate synthase Collagen_bind_2 PF12904.7 AJZ76685.1 - 0.069 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase APS_kinase PF01583.20 AJZ76686.1 - 3.5e-45 153.7 0.0 4.1e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 AJZ76686.1 - 2.8e-05 24.3 0.0 5.1e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AJZ76686.1 - 0.0003 21.3 0.0 0.00052 20.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 AJZ76686.1 - 0.0013 18.7 0.0 0.017 14.9 0.0 2.2 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 AJZ76686.1 - 0.0073 15.8 0.1 0.038 13.4 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 AJZ76686.1 - 0.013 16.0 0.0 0.017 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain Mlp PF03304.13 AJZ76686.1 - 0.034 14.4 0.4 0.072 13.3 0.1 1.8 1 1 1 2 2 2 0 Mlp lipoprotein family AAA_28 PF13521.6 AJZ76686.1 - 0.04 14.2 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AJZ76686.1 - 0.055 12.7 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 AJZ76686.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HTH_45 PF14947.6 AJZ76688.1 - 4e-09 36.3 0.1 4.7e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_27 PF13463.6 AJZ76688.1 - 4.5e-05 23.8 0.1 6.1e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4364 PF14277.6 AJZ76688.1 - 0.00016 21.5 0.1 0.00017 21.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) MarR_2 PF12802.7 AJZ76688.1 - 0.0002 21.2 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 MarR family DUF1495 PF07381.11 AJZ76688.1 - 0.0037 17.0 0.1 0.0091 15.8 0.0 1.6 1 1 1 2 2 2 1 Winged helix DNA-binding domain (DUF1495) Mrr_N PF14338.6 AJZ76688.1 - 0.027 14.6 0.0 0.37 11.0 0.1 2.0 1 1 1 2 2 2 0 Mrr N-terminal domain TrmB PF01978.19 AJZ76688.1 - 0.052 13.4 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2513 PF10711.9 AJZ76688.1 - 0.075 13.3 0.0 0.09 13.1 0.0 1.2 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) S10_plectin PF03501.15 AJZ76688.1 - 0.093 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Plectin/S10 domain HhH-GPD PF00730.25 AJZ76689.1 - 8.7e-25 87.3 0.1 1.3e-24 86.7 0.1 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AJZ76689.1 - 4.9e-08 32.4 0.0 2.7e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif AGOG PF09171.10 AJZ76689.1 - 0.0016 17.8 0.2 0.0044 16.4 0.0 1.7 2 0 0 2 2 2 1 N-glycosylase/DNA lyase DUF2400 PF09674.10 AJZ76689.1 - 0.0062 16.6 0.0 0.014 15.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2400) HHH_5 PF14520.6 AJZ76689.1 - 0.019 15.6 0.4 0.88 10.2 0.1 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 AJZ76689.1 - 0.58 10.6 3.5 1.1 9.7 3.5 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III IBR PF01485.21 AJZ76690.1 - 0.001 19.3 1.8 0.0013 18.9 1.5 1.3 1 1 0 1 1 1 1 IBR domain, a half RING-finger domain zinc_ribbon_4 PF13717.6 AJZ76690.1 - 0.0017 18.2 3.4 0.047 13.6 3.4 2.1 1 1 0 1 1 1 1 zinc-ribbon domain UPF0547 PF10571.9 AJZ76690.1 - 0.0019 18.3 2.2 0.8 9.9 0.1 2.1 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 CpXC PF14353.6 AJZ76690.1 - 0.0036 17.3 2.5 8.7 6.4 0.3 2.0 1 1 0 1 1 1 0 CpXC protein YacG PF03884.14 AJZ76690.1 - 0.0049 16.6 0.4 2.2 8.1 0.1 2.1 2 0 0 2 2 2 2 DNA gyrase inhibitor YacG OrfB_Zn_ribbon PF07282.11 AJZ76690.1 - 0.0097 15.8 0.9 0.014 15.3 0.7 1.4 1 1 0 1 1 1 1 Putative transposase DNA-binding domain Ribosomal_S27e PF01667.17 AJZ76690.1 - 0.011 15.4 2.2 0.051 13.3 2.2 1.8 1 1 0 1 1 1 0 Ribosomal protein S27 zf-H2C2_5 PF13909.6 AJZ76690.1 - 0.011 15.4 3.9 0.062 13.1 0.6 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-ribbon_3 PF13248.6 AJZ76690.1 - 0.014 14.8 2.5 0.75 9.3 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 AJZ76690.1 - 0.017 15.0 5.5 0.11 12.5 4.2 2.1 1 1 1 2 2 2 0 PhnA Zinc-Ribbon zf-C2H2_4 PF13894.6 AJZ76690.1 - 0.023 15.5 1.0 2 9.4 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger HypA PF01155.19 AJZ76690.1 - 0.027 14.5 0.3 0.028 14.5 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ACC PF17848.1 AJZ76690.1 - 0.033 14.2 3.1 3.1 7.9 0.3 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain TF_Zn_Ribbon PF08271.12 AJZ76690.1 - 0.043 13.3 2.4 5.1 6.7 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding RIG-I_C-RD PF11648.8 AJZ76690.1 - 0.051 13.8 0.2 0.053 13.8 0.2 1.0 1 0 0 1 1 1 0 C-terminal domain of RIG-I zinc-ribbons_6 PF07191.12 AJZ76690.1 - 0.052 13.5 0.8 0.068 13.2 0.8 1.2 1 0 0 1 1 1 0 zinc-ribbons PADR1 PF08063.12 AJZ76690.1 - 0.1 12.4 1.4 5.7 6.8 0.1 2.1 2 0 0 2 2 2 0 PADR1 (NUC008) domain Ogr_Delta PF04606.12 AJZ76690.1 - 0.11 12.5 2.3 3.5 7.7 0.1 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-DNL PF05180.12 AJZ76690.1 - 0.19 11.7 2.2 0.77 9.7 2.2 1.9 1 1 0 1 1 1 0 DNL zinc finger zf-RING_7 PF02591.15 AJZ76690.1 - 0.2 11.8 2.0 2.9 8.1 0.0 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain zinc_ribbon_9 PF14369.6 AJZ76690.1 - 0.37 11.1 5.4 11 6.4 5.9 2.1 1 1 1 2 2 2 0 zinc-ribbon zf-H2C2_2 PF13465.6 AJZ76690.1 - 0.39 11.2 4.4 9.9 6.8 0.6 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 AJZ76690.1 - 0.41 10.8 5.6 7 6.8 5.7 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.12 AJZ76690.1 - 0.43 10.9 4.8 1.7 9.0 0.6 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pro_isomerase PF00160.21 AJZ76691.1 - 1.8e-50 171.3 0.0 2.1e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CobA_CobO_BtuR PF02572.15 AJZ76692.1 - 1.2e-63 214.5 1.0 1.3e-63 214.4 1.0 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ATPase_2 PF01637.18 AJZ76692.1 - 0.003 17.5 0.6 0.0037 17.2 0.6 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 AJZ76692.1 - 0.0037 17.7 2.4 0.0082 16.6 2.4 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AJZ76692.1 - 0.0038 17.3 0.8 0.0097 15.9 0.8 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AJZ76692.1 - 0.01 15.6 3.2 1.2 8.8 0.3 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein ELP6 PF09807.9 AJZ76692.1 - 0.03 13.7 0.4 0.12 11.8 0.1 1.7 1 1 1 2 2 2 0 Elongation complex protein 6 AAA_24 PF13479.6 AJZ76692.1 - 0.071 12.8 0.4 0.23 11.2 0.2 1.8 1 1 1 2 2 2 0 AAA domain CbiA PF01656.23 AJZ76692.1 - 0.35 10.9 1.3 0.75 9.9 0.3 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 AJZ76692.1 - 2 8.0 5.7 5.8 6.5 0.6 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CbiG_N PF11760.8 AJZ76693.1 - 3.4e-33 113.5 0.1 5.9e-33 112.7 0.1 1.4 1 0 0 1 1 1 1 Cobalamin synthesis G N-terminal CbiG_C PF01890.16 AJZ76693.1 - 1.1e-27 96.8 0.0 2.5e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus CbiG_mid PF11761.8 AJZ76693.1 - 2.6e-16 59.5 0.0 5.2e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Cobalamin biosynthesis central region DUF3700 PF12481.8 AJZ76693.1 - 0.024 14.1 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein UME PF08064.13 AJZ76693.1 - 0.039 13.9 0.1 4.9 7.1 0.0 2.8 3 0 0 3 3 3 0 UME (NUC010) domain LSM PF01423.22 AJZ76694.1 - 1.6e-19 69.4 1.9 1.8e-19 69.2 1.9 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 AJZ76694.1 - 0.0089 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Hfq protein BrnA_antitoxin PF14384.6 AJZ76694.1 - 0.054 14.0 0.2 0.13 12.7 0.2 1.6 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system CutA1 PF03091.15 AJZ76695.1 - 2.5e-32 110.7 0.9 2.7e-32 110.5 0.9 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein PAS_6 PF08348.11 AJZ76695.1 - 0.021 14.7 0.2 0.032 14.1 0.2 1.3 1 0 0 1 1 1 0 YheO-like PAS domain Radical_SAM PF04055.21 AJZ76696.1 - 1.4e-16 61.4 0.1 1.4e-16 61.4 0.1 2.5 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_14 PF13394.6 AJZ76696.1 - 3.9e-06 27.0 0.0 3.9e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AJZ76696.1 - 7.8e-06 26.2 0.0 1.8e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain UDPG_MGDP_dh_N PF03721.14 AJZ76697.1 - 1.2e-35 122.8 0.0 2.7e-35 121.6 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AJZ76697.1 - 1.1e-23 83.2 0.1 2.3e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AJZ76697.1 - 1.3e-23 83.4 0.0 2.7e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 2-Hacid_dh_C PF02826.19 AJZ76697.1 - 5.4e-06 25.9 0.1 0.4 10.0 0.0 3.4 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AJZ76697.1 - 0.00022 21.4 0.0 0.0013 18.9 0.0 2.3 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DpaA_N PF16924.5 AJZ76697.1 - 0.00066 19.8 0.2 2.3 8.3 0.0 3.0 3 0 0 3 3 3 2 Dipicolinate synthase subunit A N-terminal domain NAD_Gly3P_dh_N PF01210.23 AJZ76697.1 - 0.0029 17.6 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_11 PF14833.6 AJZ76697.1 - 0.0035 17.6 0.4 0.0068 16.6 0.4 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 AJZ76697.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SRR1 PF07985.12 AJZ76697.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 SRR1 F420_oxidored PF03807.17 AJZ76697.1 - 0.14 12.7 0.6 35 5.1 0.2 3.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TEX19 PF15553.6 AJZ76698.1 - 0.059 13.3 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 Methyltransf_31 PF13847.6 AJZ76699.1 - 1e-15 57.8 0.2 2.1e-15 56.9 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJZ76699.1 - 1e-13 51.7 0.0 1.9e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJZ76699.1 - 8.7e-13 48.7 0.0 1.4e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJZ76699.1 - 1.5e-11 44.9 0.0 4.3e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJZ76699.1 - 6.6e-09 35.8 0.0 8.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 AJZ76699.1 - 0.00016 21.4 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 AJZ76699.1 - 0.00076 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 AJZ76699.1 - 0.0026 17.3 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 AJZ76699.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Sulfotransfer_1 PF00685.27 AJZ76700.1 - 6e-28 98.1 1.3 7.6e-28 97.7 1.3 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 AJZ76700.1 - 3.2e-15 57.1 0.1 6.2e-10 39.8 0.2 3.1 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 AJZ76700.1 - 0.0041 17.1 0.8 0.01 15.8 0.8 1.7 1 1 0 1 1 1 1 Sulfotransferase family Glycos_transf_2 PF00535.26 AJZ76701.1 - 1.2e-25 90.3 0.0 2.2e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AJZ76701.1 - 1.1e-18 68.0 0.0 1.7e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AJZ76701.1 - 7.9e-08 32.4 0.0 1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AJZ76701.1 - 0.00043 19.8 0.0 0.00069 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 AJZ76701.1 - 0.083 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 CmcI PF04989.12 AJZ76702.1 - 1.8e-85 285.8 0.0 2.4e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_24 PF13578.6 AJZ76702.1 - 1.3e-09 39.0 0.0 2.2e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TylF PF05711.11 AJZ76702.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) GDP_Man_Dehyd PF16363.5 AJZ76703.1 - 2.6e-33 115.9 0.0 8.1e-33 114.2 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AJZ76703.1 - 1.3e-29 103.3 0.0 1.7e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AJZ76703.1 - 1.7e-13 50.4 1.5 4.8e-13 48.9 1.5 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AJZ76703.1 - 1.8e-07 30.5 0.0 2.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AJZ76703.1 - 2.2e-06 27.0 0.0 3.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AJZ76703.1 - 0.0001 21.6 0.5 0.0001 21.6 0.5 1.9 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.25 AJZ76703.1 - 0.11 12.0 0.4 1 8.8 0.4 2.2 1 1 0 1 1 1 0 short chain dehydrogenase GFO_IDH_MocA PF01408.22 AJZ76704.1 - 0.00014 22.6 0.0 0.00039 21.2 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold PIG-L PF02585.17 AJZ76705.1 - 5.5e-19 69.1 0.0 7.2e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glyco_trans_4_2 PF13477.6 AJZ76705.1 - 0.0077 16.3 0.2 0.029 14.4 0.1 1.9 1 1 1 2 2 2 1 Glycosyl transferase 4-like Ldh_1_C PF02866.18 AJZ76705.1 - 0.037 14.0 0.4 1.8 8.5 0.3 2.4 2 0 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain AAA_lid_10 PF17872.1 AJZ76705.1 - 0.042 14.0 1.0 0.55 10.4 0.5 2.5 3 0 0 3 3 3 0 AAA lid domain TBPIP_N PF15517.6 AJZ76705.1 - 0.067 13.2 0.4 0.34 11.0 0.4 2.2 2 0 0 2 2 2 0 TBP-interacting protein N-terminus DUF3626 PF12294.8 AJZ76705.1 - 0.15 11.0 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) DegT_DnrJ_EryC1 PF01041.17 AJZ76706.1 - 8.2e-99 331.3 0.0 9.6e-99 331.1 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AJZ76706.1 - 1.3e-05 24.6 0.0 5.3e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AJZ76706.1 - 0.0014 17.2 0.0 0.0021 16.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Polyketide_cyc2 PF10604.9 AJZ76708.1 - 3.9e-11 43.4 0.3 5.1e-11 43.0 0.3 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AJZ76708.1 - 1.4e-07 31.8 0.1 2.4e-07 31.0 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 AJZ76708.1 - 6.1e-07 29.7 0.2 8.6e-07 29.2 0.2 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein FMN_red PF03358.15 AJZ76709.1 - 5e-16 58.8 0.0 7.7e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Rieske PF00355.26 AJZ76709.1 - 1.1e-11 44.5 0.0 2.9e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Flavodoxin_2 PF02525.17 AJZ76709.1 - 7e-05 22.6 0.0 9.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Rieske_2 PF13806.6 AJZ76709.1 - 0.051 13.5 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain HTH_5 PF01022.20 AJZ76710.1 - 2.3e-07 30.6 0.0 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 AJZ76710.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 AJZ76710.1 - 0.046 13.4 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) NUMOD1 PF07453.13 AJZ76710.1 - 0.11 12.8 0.2 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 NUMOD1 domain Copper-bind PF00127.20 AJZ76711.1 - 2.5e-09 37.5 0.0 3.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJZ76711.1 - 5.4e-09 36.1 0.1 6.9e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 Cupredoxin-like domain DUF4981 PF16353.5 AJZ76711.1 - 0.11 12.9 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function(DUF4981) ABC_tran PF00005.27 AJZ76712.1 - 1.1e-29 103.7 0.0 1.6e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AJZ76712.1 - 3.9e-11 43.3 0.0 9.3e-05 22.4 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AJZ76712.1 - 3.9e-09 36.3 0.1 2e-08 34.0 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AJZ76712.1 - 1e-06 28.7 0.0 0.0023 17.7 0.0 2.2 1 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 AJZ76712.1 - 1.5e-05 25.3 0.0 3.7e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AJZ76712.1 - 0.00082 19.9 0.0 0.002 18.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.15 AJZ76712.1 - 0.001 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain P22_CoatProtein PF11651.8 AJZ76712.1 - 0.0016 17.1 0.0 0.0025 16.5 0.0 1.2 1 0 0 1 1 1 1 P22 coat protein - gene protein 5 RsgA_GTPase PF03193.16 AJZ76712.1 - 0.0017 18.2 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AJZ76712.1 - 0.0076 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.22 AJZ76712.1 - 0.0091 15.2 0.0 0.011 14.9 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain TniB PF05621.11 AJZ76712.1 - 0.011 15.1 0.3 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 AJZ76712.1 - 0.012 16.0 0.1 0.015 15.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AJZ76712.1 - 0.023 14.4 0.1 0.056 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AJZ76712.1 - 0.026 15.0 0.3 0.18 12.2 0.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AJZ76712.1 - 0.046 14.3 0.1 0.086 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AJZ76712.1 - 0.049 13.8 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AJZ76712.1 - 0.063 13.0 0.5 0.22 11.2 0.5 2.0 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 AJZ76712.1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATPase_2 PF01637.18 AJZ76712.1 - 0.082 12.8 1.3 1.1 9.1 1.3 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AJZ76712.1 - 0.089 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AJZ76712.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 AJZ76712.1 - 0.11 12.8 0.1 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AJZ76712.1 - 0.13 12.7 0.1 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase BPD_transp_1 PF00528.22 AJZ76713.1 - 4.1e-17 62.5 14.7 4.1e-17 62.5 14.7 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3413 PF11893.8 AJZ76713.1 - 0.021 14.0 6.2 0.033 13.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) CitMHS PF03600.16 AJZ76714.1 - 1.2e-53 182.3 34.0 1.2e-53 182.3 34.0 1.7 1 1 1 2 2 2 1 Citrate transporter ArsB PF02040.15 AJZ76714.1 - 6.4e-16 58.7 31.8 1.1e-15 57.9 31.8 1.3 1 1 0 1 1 1 1 Arsenical pump membrane protein DctM PF06808.12 AJZ76714.1 - 0.028 13.3 33.1 0.019 13.8 23.3 2.8 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporter, DctM component LMWPc PF01451.21 AJZ76716.1 - 1.8e-13 51.1 0.0 3e-13 50.3 0.0 1.4 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Urease_beta PF00699.20 AJZ76717.1 - 4e-41 139.0 0.0 4.7e-41 138.8 0.0 1.0 1 0 0 1 1 1 1 Urease beta subunit PapD_N PF00345.20 AJZ76717.1 - 0.037 13.9 0.0 0.05 13.5 0.0 1.4 1 1 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain GTP_EFTU PF00009.27 AJZ76718.1 - 3.6e-32 111.5 0.3 1.4e-31 109.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D4 PF14578.6 AJZ76718.1 - 5.2e-25 87.2 0.4 5.2e-25 87.2 0.4 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 IF-2 PF11987.8 AJZ76718.1 - 2.8e-23 82.0 2.4 2.2e-22 79.2 0.6 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 AJZ76718.1 - 1.8e-09 37.9 1.0 1.5e-08 34.9 0.0 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AJZ76718.1 - 3.5e-07 30.3 0.5 1.8e-06 28.0 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 AJZ76718.1 - 5e-05 23.2 0.0 0.00022 21.1 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Roc PF08477.13 AJZ76718.1 - 7.8e-05 22.9 0.0 0.00045 20.4 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 AJZ76718.1 - 0.0011 19.1 1.1 0.15 12.1 0.1 3.1 3 0 0 3 3 3 1 Dynamin family Ras PF00071.22 AJZ76718.1 - 0.018 14.6 0.2 0.081 12.5 0.0 2.1 2 0 0 2 2 2 0 Ras family DUF2171 PF09939.9 AJZ76718.1 - 0.087 13.1 0.3 0.6 10.4 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2171) DUF4577 PF15145.6 AJZ76719.1 - 0.024 14.7 1.2 0.027 14.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF5088 PF17008.5 AJZ76719.1 - 0.05 13.3 0.6 0.063 13.0 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5088) DUF4212 PF13937.6 AJZ76719.1 - 0.086 13.2 2.3 0.1 13.0 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) Vpu PF00558.19 AJZ76719.1 - 0.21 11.4 1.7 0.31 10.8 1.7 1.3 1 0 0 1 1 1 0 Vpu protein NAD_binding_1 PF00175.21 AJZ76720.1 - 1.7e-11 44.7 0.0 3.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AJZ76720.1 - 2.5e-09 37.4 0.0 3.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AJZ76720.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain U3_assoc_6 PF08640.11 AJZ76720.1 - 0.14 12.2 0.2 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Methyltransf_34 PF11312.8 AJZ76720.1 - 0.17 11.1 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Fer2_3 PF13085.6 AJZ76721.1 - 2.6e-32 111.1 0.7 4.7e-32 110.2 0.0 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 AJZ76721.1 - 6.5e-12 45.7 3.4 1.3e-11 44.8 1.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJZ76721.1 - 4.4e-10 39.5 2.0 4.4e-10 39.5 2.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AJZ76721.1 - 2.5e-08 34.3 12.1 6.3e-07 29.8 3.0 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJZ76721.1 - 5.4e-08 32.9 12.8 7.6e-07 29.2 3.5 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AJZ76721.1 - 3.9e-07 30.6 4.9 3.9e-07 30.6 4.9 2.8 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AJZ76721.1 - 4.3e-07 30.8 1.8 4.3e-07 30.8 1.8 2.3 3 0 0 3 3 2 1 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 AJZ76721.1 - 3.8e-06 27.1 2.2 0.057 13.6 0.2 2.7 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.27 AJZ76721.1 - 5.6e-05 23.0 0.2 5.6e-05 23.0 0.2 1.8 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 AJZ76721.1 - 0.00012 21.8 1.6 0.00012 21.8 1.6 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 AJZ76721.1 - 0.018 15.1 4.1 0.018 15.1 4.1 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_2 PF12797.7 AJZ76721.1 - 0.024 14.7 2.1 0.024 14.7 2.1 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_4 PF12800.7 AJZ76721.1 - 0.1 13.1 1.1 0.1 13.1 1.1 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_21 PF14697.6 AJZ76721.1 - 0.11 12.6 12.9 0.21 11.7 8.5 3.0 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AJZ76721.1 - 0.95 10.6 21.5 0.37 11.8 4.6 3.2 3 1 0 3 3 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 AJZ76721.1 - 6.1 7.8 13.3 2.9 8.8 3.5 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain Lyase_1 PF00206.20 AJZ76722.1 - 5.2e-55 187.0 0.4 8.1e-55 186.4 0.1 1.5 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 AJZ76722.1 - 1.3e-15 57.8 0.2 5.4e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Rop-like PF05082.13 AJZ76722.1 - 0.079 12.8 0.6 0.3 10.9 0.6 2.0 1 0 0 1 1 1 0 Rop-like AAA PF00004.29 AJZ76723.1 - 2.1e-14 54.0 0.1 5.9e-14 52.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AJZ76723.1 - 2.6e-09 37.0 0.0 1.4e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AJZ76723.1 - 1e-05 25.8 0.1 0.0011 19.2 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 AJZ76723.1 - 1.6e-05 24.9 0.0 4.4e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 AJZ76723.1 - 2.2e-05 23.9 0.0 5.6e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 AJZ76723.1 - 8.4e-05 22.7 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AJZ76723.1 - 0.00011 22.6 0.0 0.00057 20.3 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 AJZ76723.1 - 0.00012 22.1 0.0 0.00054 19.9 0.0 2.0 1 1 1 2 2 2 1 NTPase AAA_18 PF13238.6 AJZ76723.1 - 0.00016 22.2 0.0 0.00038 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_8 PF12780.7 AJZ76723.1 - 0.00039 19.8 0.0 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 AJZ76723.1 - 0.0004 20.4 0.1 0.0013 18.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 AJZ76723.1 - 0.00053 20.0 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 AJZ76723.1 - 0.0013 19.0 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain RFC1 PF08519.12 AJZ76723.1 - 0.0019 18.4 0.1 0.0086 16.2 0.1 2.1 1 1 0 1 1 1 1 Replication factor RFC1 C terminal domain NACHT PF05729.12 AJZ76723.1 - 0.0039 17.1 0.0 0.11 12.4 0.0 2.7 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.6 AJZ76723.1 - 0.0043 17.5 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 AJZ76723.1 - 0.0086 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 AJZ76723.1 - 0.0097 15.7 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AJZ76723.1 - 0.017 14.5 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 AJZ76723.1 - 0.019 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 AJZ76723.1 - 0.02 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 AJZ76723.1 - 0.039 14.0 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 AJZ76723.1 - 0.041 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AJZ76723.1 - 0.05 12.8 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 AJZ76723.1 - 0.067 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AJZ76723.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 AJZ76723.1 - 0.17 12.2 0.5 0.61 10.4 0.2 2.0 1 1 0 2 2 2 0 AAA domain Carboxyl_trans PF01039.22 AJZ76725.1 - 2.9e-180 600.1 0.4 3.3e-180 600.0 0.4 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AJZ76725.1 - 5.7e-07 29.3 0.1 1.4e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) Proton_antipo_M PF00361.20 AJZ76726.1 - 7.3e-63 212.5 33.5 2e-60 204.5 33.5 2.7 1 1 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AJZ76726.1 - 1.3e-12 47.5 2.3 1.3e-12 47.5 2.3 3.5 4 0 0 4 4 4 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_C PF01010.19 AJZ76726.1 - 0.00033 20.4 0.6 0.035 13.7 0.3 2.3 1 1 1 2 2 2 2 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Peptidase_M10 PF00413.24 AJZ76727.1 - 4e-09 36.5 0.1 2.3e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 AJZ76727.1 - 0.0028 17.3 0.3 0.0036 16.9 0.3 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase DUF2268 PF10026.9 AJZ76727.1 - 0.0041 16.7 0.0 0.084 12.4 0.0 2.1 2 0 0 2 2 2 1 Predicted Zn-dependent protease (DUF2268) Reprolysin_5 PF13688.6 AJZ76727.1 - 0.0092 16.1 0.2 0.012 15.8 0.2 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 DUF4953 PF16313.5 AJZ76727.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 AJZ76727.1 - 0.014 14.3 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 AJZ76727.1 - 0.021 15.4 0.4 0.033 14.7 0.4 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Terminase_GpA PF05876.12 AJZ76727.1 - 0.19 10.2 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) HTH_45 PF14947.6 AJZ76728.1 - 1.8e-12 47.1 0.5 2.7e-12 46.5 0.5 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DUF2653 PF10850.8 AJZ76728.1 - 0.022 15.0 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) Baculo_LEF5 PF04838.12 AJZ76728.1 - 0.059 13.4 0.1 0.097 12.7 0.1 1.4 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 Met_10 PF02475.16 AJZ76730.1 - 8.1e-60 202.0 0.0 1e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 AJZ76730.1 - 1.9e-05 24.2 0.1 3.4e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 AJZ76730.1 - 0.00094 18.8 0.1 0.0013 18.3 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRM PF02005.16 AJZ76730.1 - 0.0079 15.4 0.1 0.0092 15.2 0.1 1.4 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase ADH_zinc_N PF00107.26 AJZ76730.1 - 0.013 15.4 0.0 0.031 14.3 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltrans_SAM PF10672.9 AJZ76730.1 - 0.021 14.0 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 AJZ76730.1 - 0.022 14.4 0.0 0.078 12.6 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 AJZ76730.1 - 0.041 13.4 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 AJZ76730.1 - 0.073 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Lysine methyltransferase MscL PF01741.18 AJZ76731.1 - 5.8e-21 75.0 5.2 6.3e-21 74.9 5.2 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL FtsX PF02687.21 AJZ76731.1 - 0.023 15.1 3.4 0.036 14.5 3.4 1.2 1 0 0 1 1 1 0 FtsX-like permease family DUF3951 PF13131.6 AJZ76731.1 - 4.1 7.7 8.3 4.6 7.5 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) FeoB_associated PF12669.7 AJZ76731.1 - 6.1 7.3 7.1 11 6.5 1.1 2.4 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Ribul_P_3_epim PF00834.19 AJZ76732.1 - 3.8e-52 176.6 0.1 5.7e-52 176.0 0.1 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Transketolase_N PF00456.21 AJZ76732.1 - 5.5e-45 153.8 0.3 1.4e-43 149.2 0.3 2.2 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 AJZ76732.1 - 0.00016 20.8 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 AJZ76732.1 - 0.00024 20.4 0.0 0.02 14.1 0.0 2.4 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AJZ76732.1 - 0.0012 18.6 0.0 0.0033 17.2 0.0 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 AJZ76732.1 - 0.0019 17.1 1.3 0.078 11.8 0.0 2.9 2 1 1 3 3 3 1 XFP N-terminal domain Transket_pyr PF02779.24 AJZ76733.1 - 1.7e-32 112.5 0.0 2.3e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AJZ76733.1 - 1e-29 102.9 0.0 1.7e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 AJZ76733.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Phage_fiber_2 PF03406.13 AJZ76733.1 - 0.086 12.4 0.1 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 Phage tail fibre repeat Lactamase_B PF00753.27 AJZ76734.1 - 2.2e-19 70.2 0.1 8.5e-19 68.3 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Rhodanese PF00581.20 AJZ76734.1 - 5.6e-12 46.1 0.0 1.5e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Lactamase_B_3 PF13483.6 AJZ76734.1 - 0.0059 16.5 0.0 0.0094 15.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 AJZ76734.1 - 0.02 14.4 0.2 0.037 13.5 0.2 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_5 PF14597.6 AJZ76734.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily FAD_binding_2 PF00890.24 AJZ76735.1 - 0.017 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 AJZ76735.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3600 PF12207.8 AJZ76735.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) FAD_binding_3 PF01494.19 AJZ76735.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 AJZ76735.1 - 0.13 11.9 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase tRNA-synt_2d PF01409.20 AJZ76736.1 - 3.2e-87 292.1 0.0 5.7e-87 291.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 AJZ76736.1 - 1.1e-06 28.2 0.0 2.6e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD3 PF18553.1 AJZ76736.1 - 2.7e-06 27.6 0.4 1.6e-05 25.1 0.1 2.6 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 AJZ76736.1 - 0.0035 16.5 0.0 0.019 14.0 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DprA_WH PF17782.1 AJZ76736.1 - 0.0062 16.6 0.1 6.1 7.0 0.0 3.2 3 0 0 3 3 3 1 DprA winged helix domain HTH_11 PF08279.12 AJZ76736.1 - 0.029 14.3 0.7 0.38 10.7 0.7 2.3 2 0 0 2 2 2 0 HTH domain HTH_9 PF08221.11 AJZ76736.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain AsnC_trans_reg PF01037.21 AJZ76737.1 - 4.9e-12 45.6 0.0 5.7e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 AJZ76737.1 - 0.0008 19.4 0.0 0.00094 19.2 0.0 1.1 1 0 0 1 1 1 1 NapD protein GYD PF08734.11 AJZ76737.1 - 0.025 14.5 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 GYD domain Rogdi_lz PF10259.9 AJZ76738.1 - 0.015 14.8 1.2 0.28 10.6 0.1 2.1 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein PTPS PF01242.19 AJZ76739.1 - 2.8e-19 69.3 0.0 6.1e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase TatD_DNase PF01026.21 AJZ76740.1 - 1e-38 133.2 0.0 1.2e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Adenylsucc_synt PF00709.21 AJZ76741.1 - 3.9e-83 279.7 0.9 1e-38 133.4 0.1 3.0 1 1 2 3 3 3 3 Adenylosuccinate synthetase eIF-5_eIF-2B PF01873.17 AJZ76742.1 - 7.4e-32 109.7 0.0 9e-32 109.4 0.0 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 AJZ76742.1 - 0.00012 21.5 1.5 0.00021 20.7 1.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Lar_restr_allev PF14354.6 AJZ76742.1 - 0.0021 18.4 0.6 0.0032 17.8 0.6 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar PDCD2_C PF04194.13 AJZ76742.1 - 0.0097 16.0 0.0 0.013 15.6 0.0 1.3 1 1 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Elf1 PF05129.13 AJZ76742.1 - 0.012 15.7 0.9 0.023 14.7 0.2 1.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-TFIIB PF13453.6 AJZ76742.1 - 0.029 13.7 2.4 0.057 12.8 2.4 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger RIO1 PF01163.22 AJZ76743.1 - 7.1e-53 179.0 0.0 1.2e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 AJZ76743.1 - 0.0038 17.2 0.0 0.37 10.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family MFS_Mycoplasma PF07672.13 AJZ76743.1 - 0.024 13.9 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Mycoplasma MFS transporter HATPase_c PF02518.26 AJZ76744.1 - 5.1e-20 72.1 0.4 8.1e-20 71.4 0.4 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AJZ76744.1 - 2.1e-10 40.4 0.4 4.6e-10 39.3 0.4 1.6 1 0 0 1 1 1 1 GHKL domain HisKA PF00512.25 AJZ76744.1 - 4.2e-10 39.5 1.4 6.6e-10 38.9 0.1 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AJZ76744.1 - 2.2e-05 24.3 0.0 5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AJZ76744.1 - 0.026 14.5 0.0 0.075 13.0 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Cas_Cas4 PF01930.17 AJZ76744.1 - 0.044 13.9 0.3 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF83 STN PF07660.14 AJZ76744.1 - 0.06 13.2 0.1 0.23 11.3 0.1 2.1 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain MAP70 PF07058.11 AJZ76744.1 - 0.17 10.6 6.1 0.23 10.1 6.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 Mei5_like PF17021.5 AJZ76744.1 - 1.3 9.1 7.6 8.6 6.4 0.1 2.4 1 1 0 2 2 2 0 Putative double-strand recombination repair-like DUF4923 PF16270.5 AJZ76746.1 - 0.019 14.8 0.1 0.023 14.6 0.1 1.1 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) UBA_2 PF08587.11 AJZ76746.1 - 0.097 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) RNA_pol_Rpc34 PF05158.12 AJZ76747.1 - 6.4e-06 25.8 0.0 6.4e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR PF01047.22 AJZ76747.1 - 1e-05 25.4 0.1 1.5e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 MarR family B-block_TFIIIC PF04182.12 AJZ76747.1 - 0.051 13.7 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC MFS_1 PF07690.16 AJZ76748.1 - 6.1e-45 153.7 75.8 2.2e-42 145.3 42.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AJZ76748.1 - 3.9e-06 26.0 15.0 3.9e-06 26.0 15.0 3.2 2 2 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 AJZ76748.1 - 0.0012 17.5 5.2 0.0012 17.5 5.2 4.3 3 1 0 3 3 3 2 MFS/sugar transport protein MASE3 PF17159.4 AJZ76748.1 - 0.0034 17.0 7.4 0.0034 17.0 7.4 4.3 1 1 2 4 4 4 1 Membrane-associated sensor domain Thioredoxin_4 PF13462.6 AJZ76749.1 - 5.8e-40 137.2 0.0 6.8e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AJZ76749.1 - 3.8e-17 62.7 0.0 4.5e-16 59.2 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJZ76749.1 - 3e-10 40.5 0.0 4.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 AJZ76749.1 - 0.00029 20.6 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AJZ76749.1 - 0.0018 18.6 0.0 0.22 11.9 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 AJZ76749.1 - 0.006 16.6 0.0 0.44 10.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 AJZ76749.1 - 0.011 15.8 0.0 0.99 9.5 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain QueT PF06177.11 AJZ76750.1 - 0.007 16.7 11.4 0.0088 16.4 11.4 1.0 1 0 0 1 1 1 1 QueT transporter Oleosin PF01277.17 AJZ76750.1 - 0.063 13.0 1.7 0.07 12.9 0.7 1.6 1 1 0 1 1 1 0 Oleosin Proteasome PF00227.26 AJZ76751.1 - 3.4e-52 176.7 0.6 4.6e-52 176.3 0.6 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AJZ76751.1 - 7.4e-11 41.5 2.8 1.3e-10 40.8 0.2 2.5 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature HTH_5 PF01022.20 AJZ76752.1 - 2.7e-11 43.1 0.0 5.1e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_45 PF14947.6 AJZ76752.1 - 4.7e-05 23.3 1.1 6.9e-05 22.8 1.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.19 AJZ76752.1 - 0.00053 19.8 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AJZ76752.1 - 0.0011 18.5 0.2 0.0023 17.5 0.2 1.6 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AJZ76752.1 - 0.0016 18.5 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AJZ76752.1 - 0.01 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix B-block_TFIIIC PF04182.12 AJZ76752.1 - 0.012 15.7 0.2 0.024 14.8 0.2 1.6 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC Phage_rep_O PF04492.13 AJZ76752.1 - 0.016 15.8 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage replication protein O HTH_Crp_2 PF13545.6 AJZ76752.1 - 0.016 15.1 0.0 0.024 14.6 0.0 1.4 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_12 PF08461.10 AJZ76752.1 - 0.018 15.0 0.1 0.063 13.2 0.0 1.9 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain DprA_WH PF17782.1 AJZ76752.1 - 0.03 14.4 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 DprA winged helix domain MarR PF01047.22 AJZ76752.1 - 0.033 14.1 0.1 0.07 13.1 0.1 1.5 1 0 0 1 1 1 0 MarR family AKNA PF12443.8 AJZ76752.1 - 0.034 14.8 0.0 0.05 14.3 0.0 1.3 1 0 0 1 1 1 0 AT-hook-containing transcription factor TFIIE_alpha PF02002.17 AJZ76752.1 - 0.047 13.6 0.3 0.06 13.2 0.3 1.1 1 0 0 1 1 1 0 TFIIE alpha subunit Rio2_N PF09202.11 AJZ76752.1 - 0.05 13.8 0.1 0.071 13.3 0.1 1.3 1 0 0 1 1 1 0 Rio2, N-terminal MarR_2 PF12802.7 AJZ76752.1 - 0.051 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 AJZ76752.1 - 0.12 12.8 0.4 0.22 11.9 0.3 1.6 1 1 0 1 1 1 0 Transcriptional regulator GATase PF00117.28 AJZ76753.1 - 2.8e-20 72.9 0.0 3.8e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJZ76753.1 - 5.2e-07 29.6 0.0 1.2e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase C26 HTS PF04204.16 AJZ76753.1 - 0.0013 17.7 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Homoserine O-succinyltransferase GATase_3 PF07685.14 AJZ76753.1 - 0.14 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ATP-grasp_5 PF13549.6 AJZ76754.1 - 8.5e-67 224.9 1.0 1.3e-66 224.3 1.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 AJZ76754.1 - 1.5e-50 170.6 0.1 2e-49 166.9 0.2 2.7 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AJZ76754.1 - 5.5e-27 94.6 2.6 6.3e-27 94.4 0.6 2.2 3 0 0 3 3 3 1 CoA binding domain CoA_binding PF02629.19 AJZ76754.1 - 1.2e-09 38.7 2.5 7.8e-09 36.1 0.3 3.3 3 0 0 3 3 3 1 CoA binding domain ATP-grasp_2 PF08442.10 AJZ76754.1 - 4e-07 29.8 1.0 8.7e-07 28.7 1.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain TPP_enzyme_M PF00205.22 AJZ76754.1 - 0.0011 18.7 0.2 1.1 9.0 0.0 3.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain GFO_IDH_MocA PF01408.22 AJZ76754.1 - 0.005 17.7 0.2 0.037 14.8 0.1 2.6 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 AJZ76754.1 - 0.017 15.6 1.9 1.4 9.3 0.4 3.9 3 1 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain ATP-grasp PF02222.22 AJZ76754.1 - 0.043 13.4 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp domain HMGL-like PF00682.19 AJZ76755.1 - 1.7e-73 247.5 0.1 2.1e-73 247.1 0.1 1.1 1 0 0 1 1 1 1 HMGL-like Semialdhyde_dh PF01118.24 AJZ76756.1 - 4.8e-35 120.6 0.0 8e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AJZ76756.1 - 1.1e-17 64.7 0.0 2e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain GFO_IDH_MocA PF01408.22 AJZ76756.1 - 0.00066 20.5 0.0 0.0015 19.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 AJZ76756.1 - 0.00099 19.4 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 AJZ76756.1 - 0.0017 18.5 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 AJZ76756.1 - 0.082 13.5 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 AJZ76756.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family BPD_transp_1 PF00528.22 AJZ76757.1 - 1.7e-24 86.6 14.8 3.1e-24 85.7 14.8 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF3043 PF11241.8 AJZ76757.1 - 0.12 12.3 0.3 0.23 11.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) HKR_ArcB_TM PF18415.1 AJZ76757.1 - 0.15 12.9 0.4 0.15 12.9 0.4 2.4 2 1 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain Tubulin PF00091.25 AJZ76758.1 - 5.4e-16 59.4 0.1 2.6e-14 53.9 0.0 2.4 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Ca_chan_IQ PF08763.11 AJZ76758.1 - 0.068 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Metallophos_2 PF12850.7 AJZ76759.1 - 1.4e-08 35.1 0.1 2.5e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AJZ76759.1 - 1.9e-08 35.1 1.1 2.8e-08 34.5 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LcrG PF07216.12 AJZ76759.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 LcrG protein DUF87 PF01935.17 AJZ76760.1 - 1.7e-37 129.7 0.8 3.6e-37 128.6 0.4 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain DUF853 PF05872.12 AJZ76760.1 - 3.1e-06 26.1 0.0 0.0089 14.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) HAS-barrel PF09378.10 AJZ76760.1 - 4.2e-05 23.6 0.2 0.00013 22.0 0.1 2.0 2 0 0 2 2 2 1 HAS barrel domain AAA_10 PF12846.7 AJZ76760.1 - 0.012 14.5 0.2 0.31 9.9 0.2 2.2 1 1 0 1 1 1 0 AAA-like domain ABC_tran PF00005.27 AJZ76760.1 - 0.017 15.6 0.1 0.074 13.6 0.1 2.0 1 1 1 2 2 2 0 ABC transporter mRNA_triPase PF02940.15 AJZ76761.1 - 0.042 13.6 0.6 0.17 11.5 0.5 1.9 1 1 0 1 1 1 0 mRNA capping enzyme, beta chain DUF108 PF01958.18 AJZ76762.1 - 6.1e-33 113.1 1.9 8.7e-33 112.6 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 AJZ76762.1 - 1.3e-17 64.5 0.2 3.2e-17 63.3 0.1 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AJZ76762.1 - 5e-06 27.3 0.2 2.5e-05 25.1 0.1 2.0 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 AJZ76762.1 - 0.00042 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 AJZ76762.1 - 0.0023 18.5 1.3 0.0044 17.6 0.2 2.0 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 AJZ76762.1 - 0.0053 17.2 0.2 0.014 15.8 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 AJZ76762.1 - 0.0097 16.0 0.6 0.033 14.3 0.1 2.1 2 2 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AJZ76762.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Thaumarchaeota_archaeon_SAT1-ASM95590v2/GCA_000955905.2_ASM95590v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Thaumarchaeota_archaeon_SAT1-ASM95590v2/GCA_000955905.2_ASM95590v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Thaumarchaeota_archaeon_SAT1-ASM95590v2/GCA_000955905.2_ASM95590v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Thaumarchaeota_archaeon_SAT1-ASM95590v2/GCA_000955905.2_ASM95590v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 16:26:12 2019 # [ok]