# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Cdc6_C PF09079.6 ABX11901.1 - 2e-20 72.2 1.2 6.1e-20 70.7 0.3 2.1 2 0 0 2 2 2 1 CDC6, C terminal AAA_22 PF13401.1 ABX11901.1 - 3.3e-14 53.1 0.2 8.7e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ABX11901.1 - 5.6e-12 45.9 0.9 2.6e-11 43.8 0.2 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ABX11901.1 - 3.2e-11 43.5 0.3 7.1e-10 39.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 ABX11901.1 - 2.6e-07 30.4 0.0 4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 ABX11901.1 - 7.6e-07 29.0 4.5 1.8e-06 27.8 2.4 2.1 1 1 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 ABX11901.1 - 1.8e-05 23.9 0.7 0.081 11.8 0.1 2.6 1 1 0 2 2 2 2 KAP family P-loop domain PIF1 PF05970.9 ABX11901.1 - 5.8e-05 22.1 0.1 0.00026 20.0 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.4 ABX11901.1 - 7.6e-05 21.8 0.1 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 ABX11901.1 - 0.00019 20.3 0.1 0.00039 19.3 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 ABX11901.1 - 0.00099 18.8 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain TrwB_AAD_bind PF10412.4 ABX11901.1 - 0.0011 17.7 0.0 0.014 14.0 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 ABX11901.1 - 0.0014 18.3 0.3 0.0043 16.7 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 ABX11901.1 - 0.0014 17.6 0.0 0.0035 16.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 ABX11901.1 - 0.0015 18.6 0.1 0.006 16.7 0.0 2.0 2 0 0 2 2 1 1 RNA helicase T2SE PF00437.15 ABX11901.1 - 0.0023 16.8 0.0 0.0058 15.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein NTPase_1 PF03266.10 ABX11901.1 - 0.0024 17.6 2.5 0.043 13.5 1.8 2.4 1 1 0 1 1 1 1 NTPase AAA_24 PF13479.1 ABX11901.1 - 0.0033 17.0 0.2 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 ABX11901.1 - 0.0036 16.4 0.4 0.27 10.3 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA_11 PF13086.1 ABX11901.1 - 0.0048 16.4 3.7 0.013 15.0 2.5 1.7 1 1 0 1 1 1 1 AAA domain AAA_32 PF13654.1 ABX11901.1 - 0.007 15.0 0.6 0.22 10.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 ABX11901.1 - 0.0098 15.0 0.0 0.025 13.7 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 ABX11901.1 - 0.01 15.6 0.9 0.072 12.9 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 ABX11901.1 - 0.13 12.1 0.1 1.1 9.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 ABX11901.1 - 0.31 10.4 1.4 2.1 7.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain DNA_pol_E_B PF04042.11 ABX11902.1 - 1.4e-25 89.8 0.0 2.5e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.2 ABX11902.1 - 1.1e-11 44.8 0.0 2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ABX11902.1 - 1.6e-06 27.6 0.0 3.5e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase tRNA_anti-codon PF01336.20 ABX11902.1 - 0.00013 21.7 0.1 0.00033 20.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2326 PF10088.4 ABX11902.1 - 0.01 15.4 0.9 0.028 14.0 0.6 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2326) DUF95 PF01944.12 ABX11903.1 - 5.5e-09 35.8 9.7 6.6e-09 35.6 6.7 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF95 Copper-bind PF00127.15 ABX11904.1 - 0.00063 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family TP_methylase PF00590.15 ABX11905.1 - 5.3e-38 130.8 0.0 6e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases bPH_3 PF14470.1 ABX11906.1 - 5.7e-07 29.7 0.7 0.0062 16.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial PH domain Vps36_ESCRT-II PF11605.3 ABX11906.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Rtt106 PF08512.7 ABX11906.1 - 0.092 12.7 0.1 3.4 7.6 0.0 2.4 2 1 0 2 2 2 0 Histone chaperone Rttp106-like Pro_isomerase PF00160.16 ABX11907.1 - 5.8e-46 156.5 0.1 9e-46 155.8 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pyr_redox_2 PF07992.9 ABX11908.1 - 2.1e-20 73.4 1.1 8.7e-09 35.5 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ABX11908.1 - 1.1e-17 64.2 0.2 1.5e-12 47.7 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ABX11908.1 - 0.00015 20.7 0.6 1.2 7.9 0.0 3.9 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ABX11908.1 - 0.004 17.2 0.0 0.29 11.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ABX11908.1 - 0.017 14.0 0.0 2.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 ABX11908.1 - 0.023 13.5 0.0 22 3.7 0.0 3.3 3 0 0 3 3 3 0 FAD binding domain NAD_binding_9 PF13454.1 ABX11908.1 - 0.027 14.2 0.1 5.9 6.6 0.0 3.3 3 1 1 4 4 4 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ABX11908.1 - 0.11 12.5 0.2 16 5.5 0.0 2.7 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ACT_7 PF13840.1 ABX11909.1 - 1.2e-06 27.9 0.2 2e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 ACT domain DapH_N PF08503.5 ABX11909.1 - 0.01 15.9 0.5 0.053 13.6 0.1 2.3 2 0 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal SecD-TM1 PF13721.1 ABX11909.1 - 0.065 13.4 0.1 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 SecD export protein N-terminal TM region HSP20 PF00011.16 ABX11910.1 - 1.7e-05 24.6 5.4 0.00036 20.3 3.7 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family PIH1 PF08190.7 ABX11910.1 - 0.012 15.0 0.1 0.014 14.8 0.1 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 YscJ_FliF PF01514.12 ABX11910.1 - 0.038 13.1 0.5 0.043 12.9 0.3 1.1 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family AAA PF00004.24 ABX11911.1 - 8.3e-101 333.4 0.0 2.1e-51 173.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 ABX11911.1 - 3.1e-22 78.2 0.0 9e-22 76.8 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 ABX11911.1 - 5.4e-16 58.9 0.2 2.8e-07 30.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 ABX11911.1 - 6.1e-15 54.8 0.0 7e-08 31.7 0.0 2.6 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 ABX11911.1 - 3.9e-14 53.5 0.0 2.2e-05 25.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ABX11911.1 - 1.2e-13 51.4 0.0 4.5e-06 26.7 0.0 3.4 3 1 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.9 ABX11911.1 - 4.8e-13 49.0 1.1 6e-05 22.7 0.2 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ABX11911.1 - 1e-12 48.3 1.3 0.0012 18.9 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 ABX11911.1 - 2e-11 43.8 0.0 4.1e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 ABX11911.1 - 4.4e-11 42.2 0.2 9.8e-11 41.1 0.1 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.7 ABX11911.1 - 9.7e-11 41.1 0.0 0.00019 20.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 ABX11911.1 - 3.6e-10 39.8 0.0 0.00015 21.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 ABX11911.1 - 4e-10 38.9 0.1 0.00036 19.3 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 ABX11911.1 - 3.9e-09 36.8 0.1 0.00034 20.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 ABX11911.1 - 6.1e-09 35.5 0.1 0.0032 16.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 ABX11911.1 - 7.1e-09 35.2 2.0 0.0028 17.3 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 ABX11911.1 - 1.5e-07 30.7 0.6 0.014 14.5 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 ABX11911.1 - 3.2e-07 29.9 0.3 0.11 12.0 0.0 4.1 2 2 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.17 ABX11911.1 - 5.5e-07 29.7 0.0 0.054 13.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 ABX11911.1 - 1.5e-06 28.2 0.1 0.063 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 ABX11911.1 - 2.2e-06 27.2 5.9 0.32 10.3 0.2 4.4 2 2 1 3 3 3 2 AAA domain AAA_3 PF07726.6 ABX11911.1 - 5.2e-06 26.1 0.0 0.022 14.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ABX11911.1 - 5.9e-06 26.6 0.1 0.19 12.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Sigma54_activ_2 PF14532.1 ABX11911.1 - 1.2e-05 25.4 0.0 0.19 11.7 0.0 2.9 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 ABX11911.1 - 1.6e-05 24.5 0.1 0.02 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 ABX11911.1 - 3.4e-05 23.1 0.2 0.28 10.4 0.1 2.7 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.8 ABX11911.1 - 4.2e-05 22.5 0.0 0.16 10.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 ABX11911.1 - 5e-05 23.1 0.2 0.018 14.7 0.0 3.5 2 2 1 3 3 3 1 Archaeal ATPase NACHT PF05729.7 ABX11911.1 - 7.8e-05 22.3 0.8 1.6 8.3 0.0 4.0 3 1 1 4 4 4 1 NACHT domain AAA_11 PF13086.1 ABX11911.1 - 8.5e-05 22.2 0.1 0.11 12.0 0.0 2.5 2 1 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 ABX11911.1 - 8.7e-05 21.5 0.2 0.16 10.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 ABX11911.1 - 0.0002 21.0 0.0 0.15 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 ABX11911.1 - 0.00022 20.3 0.1 0.44 9.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 ABX11911.1 - 0.00026 20.7 3.2 1.6 8.4 0.0 4.4 3 1 1 4 4 3 1 NTPase SKI PF01202.17 ABX11911.1 - 0.00026 20.8 0.1 0.66 9.8 0.0 2.7 3 0 0 3 3 2 2 Shikimate kinase ResIII PF04851.10 ABX11911.1 - 0.00037 20.3 0.0 0.063 13.1 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.17 ABX11911.1 - 0.00099 18.0 0.1 0.93 8.2 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Guanylate_kin PF00625.16 ABX11911.1 - 0.0019 17.6 0.6 15 5.0 0.0 4.2 3 1 1 4 4 4 0 Guanylate kinase ATP-synt_ab PF00006.20 ABX11911.1 - 0.002 17.6 0.1 0.73 9.2 0.0 2.6 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 ABX11911.1 - 0.0023 17.5 0.0 1.7 8.3 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 ABX11911.1 - 0.0031 16.4 0.0 2.3 7.0 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein CPT PF07931.7 ABX11911.1 - 0.0045 16.6 0.1 0.23 11.0 0.0 2.7 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 ABX11911.1 - 0.0084 15.2 8.2 0.36 9.9 0.0 4.0 4 1 1 5 5 3 1 KaiC Bac_DnaA PF00308.13 ABX11911.1 - 0.0093 15.6 0.0 0.55 9.8 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein KTI12 PF08433.5 ABX11911.1 - 0.023 13.9 1.6 2.3 7.3 0.0 3.2 4 0 0 4 4 4 0 Chromatin associated protein KTI12 PIF1 PF05970.9 ABX11911.1 - 0.026 13.4 0.1 3.8 6.3 0.0 2.9 2 1 1 3 3 3 0 PIF1-like helicase Viral_helicase1 PF01443.13 ABX11911.1 - 0.027 13.9 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IPT PF01745.11 ABX11911.1 - 0.032 13.3 0.3 4.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 ABX11911.1 - 0.035 13.0 0.0 1.9 7.4 0.0 2.9 2 2 1 3 3 3 0 KAP family P-loop domain Torsin PF06309.6 ABX11911.1 - 0.043 13.7 0.1 2 8.3 0.0 2.7 2 0 0 2 2 2 0 Torsin AFG1_ATPase PF03969.11 ABX11911.1 - 0.048 12.4 0.0 6.5 5.4 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase FtsK_SpoIIIE PF01580.13 ABX11911.1 - 0.059 12.8 0.2 6.1 6.2 0.0 3.3 4 0 0 4 4 3 0 FtsK/SpoIIIE family PPV_E1_C PF00519.12 ABX11911.1 - 0.17 10.4 0.0 3.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase AAA_21 PF13304.1 ABX11911.1 - 0.38 10.6 2.7 5 6.9 0.8 3.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ABX11911.1 - 0.87 9.8 6.3 15 5.8 0.0 3.7 3 1 0 3 3 3 0 AAA domain Leu_zip PF15294.1 ABX11912.1 - 6e-05 22.2 5.1 7.5e-05 21.9 3.5 1.1 1 0 0 1 1 1 1 Leucine zipper ADIP PF11559.3 ABX11912.1 - 6e-05 22.9 8.9 7.9e-05 22.6 6.2 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 ABX11912.1 - 9.9e-05 22.2 9.6 0.00014 21.7 6.6 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 ABX11912.1 - 0.00013 19.9 5.0 0.00015 19.7 3.5 1.0 1 0 0 1 1 1 1 HOOK protein HALZ PF02183.13 ABX11912.1 - 0.00016 21.3 5.7 0.0023 17.6 1.7 2.4 1 1 1 2 2 2 2 Homeobox associated leucine zipper IncA PF04156.9 ABX11912.1 - 0.00048 19.7 11.5 0.0007 19.2 8.0 1.4 1 1 0 1 1 1 1 IncA protein TMF_DNA_bd PF12329.3 ABX11912.1 - 0.0009 19.0 14.4 0.0014 18.3 10.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 ABX11912.1 - 0.0011 19.2 12.3 0.0022 18.2 8.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF904) APG6 PF04111.7 ABX11912.1 - 0.0011 18.0 4.9 0.0014 17.7 3.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 NTR2 PF15458.1 ABX11912.1 - 0.0012 18.1 6.0 0.0014 17.8 4.2 1.1 1 0 0 1 1 1 1 Nineteen complex-related protein 2 DUF3450 PF11932.3 ABX11912.1 - 0.0012 18.1 6.6 0.0017 17.6 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) V_ATPase_I PF01496.14 ABX11912.1 - 0.0023 15.8 1.0 0.003 15.5 0.7 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 ABX11912.1 - 0.0032 14.8 4.3 0.0039 14.6 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Jnk-SapK_ap_N PF09744.4 ABX11912.1 - 0.0035 17.3 5.7 0.0053 16.7 3.9 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 CENP-Q PF13094.1 ABX11912.1 - 0.0047 16.9 5.8 0.0054 16.7 4.0 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Mnd1 PF03962.10 ABX11912.1 - 0.005 16.5 0.5 0.0053 16.4 0.3 1.2 1 0 0 1 1 1 1 Mnd1 family DivIC PF04977.10 ABX11912.1 - 0.0054 16.1 12.8 0.0056 16.1 3.7 2.2 1 1 1 2 2 2 1 Septum formation initiator DUF720 PF05302.6 ABX11912.1 - 0.0062 16.2 1.6 0.0088 15.7 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF720) CCDC155 PF14662.1 ABX11912.1 - 0.0063 16.1 9.4 0.0083 15.7 6.5 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 AAA_13 PF13166.1 ABX11912.1 - 0.0066 14.9 5.1 0.0081 14.6 3.5 1.0 1 0 0 1 1 1 1 AAA domain Dapper PF15268.1 ABX11912.1 - 0.0079 15.0 1.0 0.01 14.7 0.7 1.1 1 0 0 1 1 1 1 Dapper Spc7 PF08317.6 ABX11912.1 - 0.0083 14.8 7.8 0.01 14.5 5.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein BRE1 PF08647.6 ABX11912.1 - 0.0098 15.8 8.3 0.013 15.4 5.8 1.2 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase GOLGA2L5 PF15070.1 ABX11912.1 - 0.01 14.3 6.7 0.013 14.0 4.6 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 bZIP_1 PF00170.16 ABX11912.1 - 0.013 15.4 8.6 0.014 15.3 2.8 2.2 1 1 2 3 3 3 0 bZIP transcription factor Taxilin PF09728.4 ABX11912.1 - 0.017 14.2 5.6 0.021 13.9 3.9 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein TBPIP PF07106.8 ABX11912.1 - 0.017 14.6 7.3 0.024 14.1 5.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 ABX11912.1 - 0.018 14.0 5.8 0.024 13.5 4.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 ABX11912.1 - 0.019 14.1 0.3 0.025 13.7 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Phage_GP20 PF06810.6 ABX11912.1 - 0.019 14.4 7.7 0.027 13.9 5.4 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 HAUS-augmin3 PF14932.1 ABX11912.1 - 0.021 14.0 4.0 0.026 13.7 2.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 PmbA_TldD PF01523.11 ABX11912.1 - 0.021 14.1 3.3 0.021 14.0 1.5 1.6 1 1 1 2 2 2 0 Putative modulator of DNA gyrase ATG16 PF08614.6 ABX11912.1 - 0.022 14.6 7.6 0.032 14.0 5.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIVA PF05103.8 ABX11912.1 - 0.023 14.7 6.3 0.053 13.5 4.2 1.6 1 1 0 1 1 1 0 DivIVA protein DUF3573 PF12097.3 ABX11912.1 - 0.026 13.1 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Myosin_tail_1 PF01576.14 ABX11912.1 - 0.027 12.2 8.3 0.031 11.9 5.8 1.1 1 0 0 1 1 1 0 Myosin tail BLOC1_2 PF10046.4 ABX11912.1 - 0.029 14.5 7.3 0.047 13.8 5.0 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.10 ABX11912.1 - 0.049 13.4 13.7 0.48 10.2 5.6 2.6 1 1 2 3 3 3 0 Basic region leucine zipper Trypan_PARP PF05887.6 ABX11912.1 - 0.061 13.1 23.0 0.084 12.6 16.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TPR_MLP1_2 PF07926.7 ABX11912.1 - 0.064 13.0 8.5 0.15 11.7 5.9 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.3 ABX11912.1 - 0.068 12.5 7.3 0.089 12.1 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Nsp1_C PF05064.8 ABX11912.1 - 0.068 12.8 8.9 0.1 12.2 6.1 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region CASP_C PF08172.7 ABX11912.1 - 0.075 12.0 3.0 0.1 11.6 2.1 1.1 1 0 0 1 1 1 0 CASP C terminal FliD_C PF07195.7 ABX11912.1 - 0.083 12.1 5.4 0.1 11.8 3.8 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus HlyD PF00529.15 ABX11912.1 - 0.084 12.1 2.6 0.11 11.7 1.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF4140 PF13600.1 ABX11912.1 - 0.092 13.1 5.6 0.37 11.2 3.9 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF465 PF04325.8 ABX11912.1 - 0.095 12.4 2.0 0.25 11.0 0.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF465) Tropomyosin_1 PF12718.2 ABX11912.1 - 0.1 12.4 8.8 0.15 11.9 6.1 1.3 1 0 0 1 1 1 0 Tropomyosin like RTBV_P46 PF06216.6 ABX11912.1 - 0.12 11.1 3.1 0.15 10.9 2.2 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF4366 PF14283.1 ABX11912.1 - 0.13 11.6 0.5 0.23 10.8 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF972 PF06156.8 ABX11912.1 - 0.14 12.5 6.7 0.21 11.9 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Rho_Binding PF08912.6 ABX11912.1 - 0.21 11.9 9.4 0.97 9.7 5.3 2.1 1 1 1 2 2 2 0 Rho Binding Seryl_tRNA_N PF02403.17 ABX11912.1 - 0.22 11.5 9.2 0.3 11.1 6.4 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain XhlA PF10779.4 ABX11912.1 - 0.24 11.3 7.8 0.4 10.6 5.4 1.5 1 0 0 1 1 1 0 Haemolysin XhlA DUF4600 PF15372.1 ABX11912.1 - 0.25 11.5 7.4 0.37 11.0 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DUF4164 PF13747.1 ABX11912.1 - 0.27 11.3 5.3 0.48 10.5 3.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Ax_dynein_light PF10211.4 ABX11912.1 - 0.29 10.9 7.9 0.47 10.2 5.4 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain FlaC_arch PF05377.6 ABX11912.1 - 0.31 10.9 5.5 0.29 11.0 2.4 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.1 ABX11912.1 - 0.37 10.7 8.6 1.4 8.9 6.0 1.8 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF4618 PF15397.1 ABX11912.1 - 0.37 10.0 10.3 1.9 7.7 7.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF2935 PF11155.3 ABX11912.1 - 0.38 10.8 2.4 0.5 10.4 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) GLE1 PF07817.8 ABX11912.1 - 0.45 9.3 4.5 0.59 9.0 3.1 1.1 1 0 0 1 1 1 0 GLE1-like protein TSC22 PF01166.13 ABX11912.1 - 0.46 10.4 8.5 0.2 11.6 1.1 2.7 1 1 2 3 3 2 0 TSC-22/dip/bun family DUF4407 PF14362.1 ABX11912.1 - 0.53 9.1 5.4 0.75 8.6 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CtIP_N PF10482.4 ABX11912.1 - 0.54 10.0 8.6 1.1 9.1 6.0 1.5 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF3552 PF12072.3 ABX11912.1 - 0.62 9.2 9.9 0.82 8.8 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CENP-H PF05837.7 ABX11912.1 - 0.68 10.1 9.8 1.3 9.2 6.8 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF1664 PF07889.7 ABX11912.1 - 0.71 9.6 4.3 0.95 9.2 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CALCOCO1 PF07888.6 ABX11912.1 - 0.71 8.0 8.3 0.9 7.7 5.7 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3373 PF11853.3 ABX11912.1 - 0.77 8.2 3.7 1.2 7.6 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) RNA_pol_Rpb1_1 PF04997.7 ABX11912.1 - 0.82 8.8 6.7 1 8.5 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 CorA PF01544.13 ABX11912.1 - 0.86 8.5 5.2 1.4 7.9 3.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2205 PF10224.4 ABX11912.1 - 0.91 9.1 7.9 1.6 8.3 1.5 2.4 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF4200 PF13863.1 ABX11912.1 - 1 9.3 10.6 4.2 7.3 7.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Flagellin_C PF00700.16 ABX11912.1 - 1.1 9.4 6.5 0.93 9.6 1.1 2.2 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Spc24 PF08286.6 ABX11912.1 - 1.2 8.7 7.7 2 8.1 5.3 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Pox_A_type_inc PF04508.7 ABX11912.1 - 1.3 9.0 4.7 27 4.8 0.1 3.5 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat Surfac_D-trimer PF09006.6 ABX11912.1 - 1.4 8.7 3.8 1.9 8.2 0.6 2.5 1 1 1 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation UPF0449 PF15136.1 ABX11912.1 - 1.4 9.1 4.3 2.2 8.5 2.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF2312 PF10073.4 ABX11912.1 - 1.5 8.2 7.1 2.8 7.3 0.5 3.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) TMF_TATA_bd PF12325.3 ABX11912.1 - 1.7 8.3 11.3 2.6 7.8 7.9 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Rootletin PF15035.1 ABX11912.1 - 1.9 8.4 10.6 2.6 8.0 7.4 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Snapin_Pallidin PF14712.1 ABX11912.1 - 2.2 8.6 9.7 1.9 8.8 4.6 2.0 1 1 1 2 2 2 0 Snapin/Pallidin Kinetocho_Slk19 PF12709.2 ABX11912.1 - 2.4 8.2 8.7 0.85 9.7 3.5 1.9 1 1 1 2 2 2 0 Central kinetochore-associated Prefoldin PF02996.12 ABX11912.1 - 2.5 7.7 9.7 2.3 7.8 0.6 2.2 1 1 1 2 2 2 0 Prefoldin subunit FlxA PF14282.1 ABX11912.1 - 2.5 8.1 15.0 6.4 6.7 10.4 1.6 1 1 0 1 1 1 0 FlxA-like protein Bap31 PF05529.7 ABX11912.1 - 2.7 7.4 7.1 0.44 9.9 2.5 1.4 2 0 0 2 2 1 0 B-cell receptor-associated protein 31-like DUF3782 PF12644.2 ABX11912.1 - 3.1 7.6 6.0 30 4.4 4.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) FemAB PF02388.11 ABX11912.1 - 3.4 6.2 6.0 4.5 5.8 4.2 1.1 1 0 0 1 1 1 0 FemAB family Herpes_BLRF2 PF05812.7 ABX11912.1 - 3.5 7.4 10.9 4.6 7.0 1.9 2.2 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF2681 PF10883.3 ABX11912.1 - 3.9 7.7 10.4 36 4.6 5.9 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF2681) NYD-SP28_assoc PF14775.1 ABX11912.1 - 5.4 6.7 7.1 2.2 8.0 2.8 1.9 1 1 0 2 2 1 0 Sperm tail C-terminal domain TFIIB PF00382.14 ABX11913.1 - 7.3e-30 102.5 2.3 1.5e-15 56.7 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 ABX11913.1 - 3.4e-06 26.2 0.2 8e-06 25.0 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 ABX11913.1 - 2.7e-05 23.7 0.1 0.0072 15.8 0.1 2.2 1 1 1 2 2 2 2 Cyclin, N-terminal domain HTH_11 PF08279.7 ABX11913.1 - 0.028 14.0 0.7 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 HTH domain UPF0147 PF03685.8 ABX11913.1 - 0.051 13.4 0.4 0.27 11.1 0.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0147) DUF208 PF02677.9 ABX11913.1 - 0.08 12.7 0.1 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized BCR, COG1636 DUF1059 PF06348.6 ABX11914.1 - 0.044 13.5 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) CRCB PF02537.10 ABX11915.1 - 5.8e-25 87.4 7.7 6.6e-25 87.2 5.4 1.1 1 0 0 1 1 1 1 CrcB-like protein DUF2104 PF09877.4 ABX11915.1 - 0.0071 16.2 0.3 0.0071 16.2 0.2 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2104) UPF0154 PF03672.8 ABX11915.1 - 4.9 6.8 9.4 3.9 7.1 0.2 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) DUF2669 PF10876.3 ABX11918.1 - 0.066 12.9 0.0 0.075 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2669) DUF1296 PF06972.6 ABX11918.1 - 0.16 11.9 0.9 13 5.8 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1296) CARDB PF07705.6 ABX11919.1 - 0.011 15.8 0.1 0.011 15.8 0.1 1.9 3 0 0 3 3 3 0 CARDB Chlam_OMP6 PF03504.8 ABX11919.1 - 0.12 12.6 0.2 0.29 11.4 0.1 1.6 1 1 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 TFIIB PF00382.14 ABX11920.1 - 6.8e-34 115.5 7.2 1.4e-17 63.2 0.3 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 ABX11920.1 - 2.3e-11 42.8 0.4 4e-11 42.0 0.3 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_11 PF08279.7 ABX11920.1 - 0.0018 17.9 0.3 0.073 12.7 0.0 2.9 3 0 0 3 3 3 1 HTH domain Cyclin_N PF00134.18 ABX11920.1 - 0.0023 17.4 0.2 0.076 12.5 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sigma70_r4 PF04545.11 ABX11920.1 - 0.0059 15.8 0.0 0.017 14.3 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 zf-ribbon_3 PF13248.1 ABX11920.1 - 0.0063 15.6 0.9 0.013 14.6 0.7 1.5 1 0 0 1 1 1 1 zinc-ribbon domain Sigma70_r4_2 PF08281.7 ABX11920.1 - 0.015 14.7 0.2 0.22 11.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 ABX11920.1 - 0.023 14.2 0.0 0.22 11.0 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Baculo_ME53 PF06061.6 ABX11920.1 - 0.033 13.1 0.2 0.049 12.6 0.2 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 DZR PF12773.2 ABX11920.1 - 0.04 13.7 0.8 0.09 12.6 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 ABX11920.1 - 0.053 13.0 2.2 0.12 11.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain RPA_interact_C PF14768.1 ABX11920.1 - 0.061 13.7 0.6 0.14 12.5 0.1 1.9 2 0 0 2 2 1 0 Replication protein A interacting C-terminal HTH_24 PF13412.1 ABX11920.1 - 0.084 12.2 0.2 0.94 8.9 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.1 ABX11920.1 - 0.088 12.4 2.0 0.15 11.7 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain Na_H_Exchanger PF00999.16 ABX11921.1 - 1.1e-38 132.8 47.8 1.4e-38 132.4 33.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Hemerythrin PF01814.18 ABX11922.1 - 3.3e-13 49.9 0.5 3.3e-13 49.9 0.4 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Nuf2 PF03800.9 ABX11922.1 - 0.019 14.9 0.3 0.031 14.2 0.2 1.3 1 0 0 1 1 1 0 Nuf2 family APS_kinase PF01583.15 ABX11923.1 - 1.9e-48 164.0 0.0 2.3e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 ABX11923.1 - 8.7e-07 28.9 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ABX11923.1 - 1.8e-05 25.5 0.0 3e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ABX11923.1 - 3.1e-05 24.2 0.1 0.00016 21.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ABX11923.1 - 0.00023 20.3 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 ABX11923.1 - 0.0014 17.9 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Ferrochelatase PF00762.14 ABX11923.1 - 0.024 13.6 0.0 0.29 10.0 0.0 1.4 1 1 1 2 2 2 0 Ferrochelatase AAA_28 PF13521.1 ABX11923.1 - 0.058 13.3 0.0 0.077 12.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 ABX11923.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family CPT PF07931.7 ABX11923.1 - 0.14 11.7 0.1 2.6 7.6 0.1 2.3 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Inositol_P PF00459.20 ABX11924.1 - 7.6e-52 176.2 0.1 8.3e-52 176.1 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 ABX11924.1 - 0.021 13.6 0.1 0.039 12.7 0.0 1.4 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase DUF3887 PF13026.1 ABX11924.1 - 0.72 10.1 4.4 31 4.9 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3887) CRPA PF05745.6 ABX11925.1 - 0.0039 17.0 2.6 0.0039 16.9 1.8 1.1 1 0 0 1 1 1 1 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF4212 PF13937.1 ABX11925.1 - 0.87 9.6 2.9 1.4 8.9 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4212) DUF2842 PF11003.3 ABX11925.1 - 1.3 8.9 10.1 1.4 8.8 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2842) DUF2953 PF11167.3 ABX11925.1 - 5.8 6.8 7.1 11 6.0 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) adh_short_C2 PF13561.1 ABX11926.1 - 2.4e-41 142.1 0.1 2.9e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ABX11926.1 - 2.9e-31 108.6 0.1 3.5e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ABX11926.1 - 6e-09 35.8 0.1 9.5e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ABX11926.1 - 0.00083 18.8 0.3 0.002 17.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ABX11926.1 - 0.059 13.1 0.3 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 ABX11926.1 - 0.062 12.3 0.1 0.13 11.3 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Abi_2 PF07751.6 ABX11928.1 - 0.0047 17.1 0.2 0.0083 16.3 0.1 1.5 1 0 0 1 1 1 1 Abi-like protein DUF4145 PF13643.1 ABX11928.1 - 0.024 14.4 4.9 0.032 14.0 2.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4145) Spectrin PF00435.16 ABX11928.1 - 1.2 9.4 7.2 3.8 7.8 2.0 2.4 2 1 0 2 2 2 0 Spectrin repeat Eaf7 PF07904.8 ABX11928.1 - 2.3 8.2 7.3 3.1 7.8 0.3 3.0 1 1 2 3 3 3 0 Chromatin modification-related protein EAF7 Snf7 PF03357.16 ABX11929.1 - 0.00068 19.0 4.3 0.0015 17.9 3.0 1.5 1 1 0 1 1 1 1 Snf7 Nup54 PF13874.1 ABX11929.1 - 0.018 14.6 0.9 0.031 13.9 0.7 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Filament PF00038.16 ABX11929.1 - 0.057 12.8 0.8 0.12 11.8 0.5 1.5 1 1 0 1 1 1 0 Intermediate filament protein DUF3080 PF11279.3 ABX11929.1 - 0.074 12.1 0.4 0.18 10.9 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3080) DASH_Spc34 PF08657.5 ABX11929.1 - 0.081 12.5 0.1 0.16 11.5 0.0 1.4 2 0 0 2 2 2 0 DASH complex subunit Spc34 NAS PF03059.11 ABX11929.1 - 0.11 11.6 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein Viral_P18 PF04521.8 ABX11929.1 - 0.11 11.9 0.9 0.2 11.1 0.6 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein HEXIM PF15313.1 ABX11930.1 - 0.088 12.9 0.9 0.26 11.4 0.1 1.9 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein Occludin_ELL PF07303.8 ABX11930.1 - 1.8 9.3 4.6 4 8.2 0.1 2.2 2 0 0 2 2 2 0 Occludin homology domain DUF1664 PF07889.7 ABX11931.1 - 0.00023 20.9 4.7 0.00036 20.3 3.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Spc7 PF08317.6 ABX11931.1 - 0.0013 17.4 6.1 0.0018 17.0 4.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Laminin_II PF06009.7 ABX11931.1 - 0.0023 17.6 5.7 0.0034 17.1 3.9 1.3 1 0 0 1 1 1 1 Laminin Domain II AAA_13 PF13166.1 ABX11931.1 - 0.0026 16.2 6.0 0.0026 16.2 4.1 1.1 1 0 0 1 1 1 1 AAA domain YlbD_coat PF14071.1 ABX11931.1 - 0.0047 16.9 2.0 2.1 8.4 0.5 2.2 1 1 1 2 2 2 2 Putative coat protein IncA PF04156.9 ABX11931.1 - 0.0077 15.8 8.9 0.023 14.3 6.1 1.7 1 1 0 1 1 1 1 IncA protein Flagellin_C PF00700.16 ABX11931.1 - 0.0084 16.2 2.2 0.12 12.5 0.1 2.2 1 1 1 2 2 2 1 Bacterial flagellin C-terminal helical region DUF812 PF05667.6 ABX11931.1 - 0.015 13.8 5.5 0.015 13.8 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tropomyosin_1 PF12718.2 ABX11931.1 - 0.02 14.7 15.3 0.031 14.1 9.9 2.0 1 1 0 1 1 1 0 Tropomyosin like Reo_sigmaC PF04582.7 ABX11931.1 - 0.032 13.4 0.1 0.037 13.2 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 ABX11931.1 - 0.039 13.8 5.4 0.066 13.1 3.6 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding AKNA PF12443.3 ABX11931.1 - 0.044 13.8 1.6 7 6.7 0.5 2.4 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF2009 PF09418.5 ABX11931.1 - 0.053 12.2 1.0 0.062 12.0 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Atg14 PF10186.4 ABX11931.1 - 0.058 12.3 4.7 0.065 12.1 3.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 ABX11931.1 - 0.067 12.2 4.4 0.078 12.0 3.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin PF02996.12 ABX11931.1 - 0.068 12.8 7.4 0.41 10.2 1.8 2.3 1 1 0 2 2 2 0 Prefoldin subunit Fmp27_WPPW PF10359.4 ABX11931.1 - 0.1 10.9 3.3 0.11 10.8 2.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4200 PF13863.1 ABX11931.1 - 0.11 12.4 10.6 0.14 12.1 6.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF948 PF06103.6 ABX11931.1 - 0.16 11.8 2.4 0.32 10.8 0.4 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TBPIP PF07106.8 ABX11931.1 - 0.16 11.5 8.4 0.45 10.0 5.8 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3450 PF11932.3 ABX11931.1 - 0.16 11.1 4.0 0.24 10.6 2.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CCDC-167 PF15188.1 ABX11931.1 - 0.18 11.7 6.9 0.36 10.7 4.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Mnd1 PF03962.10 ABX11931.1 - 0.22 11.1 7.7 0.26 10.9 5.3 1.4 1 1 0 1 1 1 0 Mnd1 family DUF972 PF06156.8 ABX11931.1 - 0.24 11.7 8.5 0.046 14.0 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) UK PF02512.9 ABX11931.1 - 0.25 11.7 2.1 3.5 8.0 0.3 2.8 2 1 0 2 2 2 0 Virulence determinant Rabaptin PF03528.10 ABX11931.1 - 0.35 10.7 9.8 0.7 9.8 6.8 1.6 1 1 0 1 1 1 0 Rabaptin V_ATPase_I PF01496.14 ABX11931.1 - 0.36 8.6 4.3 0.36 8.6 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4363 PF14276.1 ABX11931.1 - 0.38 10.4 3.9 0.85 9.3 2.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) Snapin_Pallidin PF14712.1 ABX11931.1 - 0.5 10.7 4.9 1.4 9.2 2.8 1.9 1 1 0 1 1 1 0 Snapin/Pallidin BLOC1_2 PF10046.4 ABX11931.1 - 0.56 10.3 6.6 2 8.5 4.6 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.16 ABX11931.1 - 0.57 10.4 6.4 3.8 7.8 4.2 2.2 1 1 1 2 2 2 0 Spectrin repeat NPV_P10 PF05531.7 ABX11931.1 - 0.7 10.1 4.0 6.3 7.1 2.7 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.15 ABX11931.1 - 0.73 9.6 13.4 3.4 7.4 0.8 2.7 1 1 2 3 3 3 0 Prefoldin subunit Syntaxin PF00804.20 ABX11931.1 - 0.75 9.9 8.8 3.1 8.0 6.1 2.0 1 1 0 1 1 1 0 Syntaxin COG2 PF06148.6 ABX11931.1 - 0.97 9.3 4.7 1.5 8.6 2.7 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaphilin PF15290.1 ABX11931.1 - 1.1 8.6 7.2 1.7 8.0 5.0 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp DUF848 PF05852.6 ABX11931.1 - 1.3 8.8 7.2 1.9 8.3 4.3 1.7 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) KH_5 PF13184.1 ABX11931.1 - 2.1 8.2 6.1 15 5.5 0.3 2.7 2 1 0 2 2 2 0 NusA-like KH domain DUF724 PF05266.9 ABX11931.1 - 3 7.4 8.1 3.8 7.1 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF4436 PF14494.1 ABX11932.1 - 0.092 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) HTH_45 PF14947.1 ABX11933.1 - 4.9e-09 35.8 0.0 5.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_27 PF13463.1 ABX11933.1 - 8.4e-07 29.2 0.0 1.1e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.2 ABX11933.1 - 4.2e-06 26.3 0.0 6.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 MarR family Mrr_N PF14338.1 ABX11933.1 - 0.0049 16.9 0.0 0.035 14.1 0.0 1.9 1 1 1 2 2 2 1 Mrr N-terminal domain DUF4364 PF14277.1 ABX11933.1 - 0.0052 16.4 0.0 0.0066 16.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) DUF1495 PF07381.6 ABX11933.1 - 0.022 14.4 0.0 0.056 13.1 0.0 1.7 1 1 1 2 2 2 0 Winged helix DNA-binding domain (DUF1495) TrmB PF01978.14 ABX11933.1 - 0.028 14.1 0.1 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.4 ABX11933.1 - 0.032 14.1 0.0 0.048 13.5 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PadR PF03551.9 ABX11933.1 - 0.048 13.4 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family RNA_pol_Rpc34 PF05158.7 ABX11933.1 - 0.052 12.7 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit MarR PF01047.17 ABX11933.1 - 0.062 13.0 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_34 PF13601.1 ABX11933.1 - 0.094 12.7 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_20 PF12840.2 ABX11933.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 ABX11933.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_24 PF13412.1 ABX11934.1 - 0.012 14.9 0.1 0.053 12.9 0.0 2.1 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_2 PF13347.1 ABX11936.1 - 0.019 13.3 0.8 0.019 13.3 0.6 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein DUF1282 PF06930.7 ABX11936.1 - 0.089 12.4 1.0 0.11 12.1 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF981 PF06168.6 ABX11936.1 - 0.11 12.2 2.6 0.12 12.1 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) NfeD PF01957.13 ABX11936.1 - 0.13 12.4 2.1 0.17 12.0 1.5 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding SKG6 PF08693.5 ABX11936.1 - 0.35 10.2 5.2 0.12 11.7 0.6 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Tetraspannin PF00335.15 ABX11936.1 - 0.44 9.7 2.7 0.52 9.5 1.8 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF2530 PF10745.4 ABX11936.1 - 0.55 10.2 3.6 0.86 9.6 2.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2530) DUF3185 PF11381.3 ABX11936.1 - 1.6 8.5 7.3 83 3.0 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) Fer4_14 PF13394.1 ABX11937.1 - 4.3e-16 59.0 0.2 1.2e-15 57.5 0.0 1.7 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 ABX11937.1 - 1.1e-14 54.7 0.2 2.6e-14 53.5 0.1 1.7 1 1 0 2 2 2 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 ABX11937.1 - 1.2e-10 41.7 0.0 1.5e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Asparaginase PF00710.15 ABX11937.1 - 0.2 10.5 0.4 0.43 9.4 0.2 1.3 1 1 0 1 1 1 0 Asparaginase SpoVIF PF14069.1 ABX11937.1 - 0.35 10.6 2.3 0.31 10.8 0.1 1.9 3 0 0 3 3 3 0 Stage VI sporulation protein F GTP_cyclohydroI PF01227.17 ABX11938.1 - 5.5e-64 214.7 0.0 6.3e-64 214.5 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 ABX11938.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein PDEase_I PF00233.14 ABX11938.1 - 0.016 14.9 0.0 0.052 13.2 0.0 1.7 1 1 1 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase DUF4172 PF13776.1 ABX11939.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) QueC PF06508.8 ABX11940.1 - 4.6e-49 166.5 0.1 5.3e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 ABX11940.1 - 8.3e-05 21.7 0.0 9.6e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 ABX11940.1 - 0.00055 19.5 0.0 0.00087 18.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 ABX11940.1 - 0.011 14.5 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.11 ABX11940.1 - 0.047 12.2 0.1 0.066 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase ThiI PF02568.9 ABX11940.1 - 0.088 12.2 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.15 ABX11940.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 PP-loop family GHMP_kinases_N PF00288.21 ABX11941.1 - 1.1e-15 57.4 3.6 2.7e-15 56.2 2.5 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ABX11941.1 - 1.1e-10 41.4 0.0 2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal ATP_bind_1 PF03029.12 ABX11942.1 - 9.2e-57 192.3 0.0 1e-56 192.1 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 ABX11942.1 - 2e-05 24.0 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 ABX11942.1 - 0.0012 18.8 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 ABX11942.1 - 0.0016 17.5 0.1 0.0041 16.1 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 ABX11942.1 - 0.0042 17.9 0.0 0.0069 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 ABX11942.1 - 0.0058 16.1 0.1 0.014 14.8 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 ABX11942.1 - 0.014 14.1 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein NACHT PF05729.7 ABX11942.1 - 0.046 13.3 0.1 0.57 9.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 ABX11942.1 - 0.048 13.9 0.1 0.096 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 ABX11942.1 - 0.049 13.0 0.2 0.7 9.2 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SRP54 PF00448.17 ABX11942.1 - 0.074 12.4 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 ABX11942.1 - 0.094 12.6 0.1 0.39 10.6 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase KaiC PF06745.8 ABX11942.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.4 1 1 0 1 1 1 0 KaiC Pentapeptide PF00805.17 ABX11942.1 - 0.18 11.1 1.3 1.1 8.5 0.0 2.7 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) UPF0104 PF03706.8 ABX11943.1 - 3.6e-24 85.5 18.3 5.2e-24 85.0 12.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) UPF0233 PF06781.7 ABX11943.1 - 0.52 9.9 6.8 4.5 6.9 0.1 3.5 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0233) adh_short PF00106.20 ABX11944.1 - 2e-38 131.9 0.0 2.6e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ABX11944.1 - 2.7e-16 59.7 0.0 3.6e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ABX11944.1 - 7.3e-13 48.8 0.2 9.3e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ABX11944.1 - 9.1e-06 25.7 0.1 3.3e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 ABX11944.1 - 1.5e-05 24.6 0.0 3.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 ABX11944.1 - 0.00065 18.6 0.1 0.00087 18.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.14 ABX11944.1 - 0.0057 15.8 0.1 0.011 14.8 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ABX11944.1 - 0.0091 16.1 0.2 0.019 15.0 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DFP PF04127.10 ABX11944.1 - 0.014 15.0 0.1 0.029 13.9 0.1 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3Beta_HSD PF01073.14 ABX11944.1 - 0.018 13.7 0.3 0.036 12.7 0.2 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.1 ABX11944.1 - 0.026 14.7 0.4 0.087 13.0 0.2 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Saccharop_dh PF03435.13 ABX11944.1 - 0.028 13.4 0.2 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 ABX11944.1 - 0.039 13.3 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 ABX11944.1 - 0.048 12.7 0.0 0.11 11.6 0.0 1.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) UBN2 PF14223.1 ABX11944.1 - 0.12 12.1 0.6 0.24 11.2 0.4 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type G10 PF01125.12 ABX11945.1 - 0.0081 15.7 0.2 1.1 8.7 0.0 2.2 2 0 0 2 2 2 2 G10 protein OrfB_Zn_ribbon PF07282.6 ABX11946.1 - 0.0045 16.6 2.1 0.1 12.2 0.1 2.3 2 0 0 2 2 2 1 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.7 ABX11946.1 - 0.0073 15.6 0.5 0.39 10.0 0.0 2.5 2 0 0 2 2 2 1 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 ABX11946.1 - 0.0076 16.0 0.5 2.4 8.0 0.0 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zf-C4pol PF14260.1 ABX11946.1 - 0.067 13.2 2.9 3.4 7.7 0.1 2.1 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-Mss51 PF13824.1 ABX11946.1 - 0.14 12.0 2.2 0.39 10.5 1.5 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn_Tnp_IS91 PF14319.1 ABX11946.1 - 0.2 11.1 1.9 1.2 8.6 0.2 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain TFIIS_C PF01096.13 ABX11946.1 - 0.28 10.8 3.6 4.2 7.0 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Nudix_N_2 PF14803.1 ABX11946.1 - 0.34 10.6 2.3 4.3 7.1 0.1 2.6 2 1 0 2 2 2 0 Nudix N-terminal Ribosomal_L32p PF01783.18 ABX11946.1 - 0.8 9.9 0.0 0.8 9.9 0.0 2.4 3 0 0 3 3 3 0 Ribosomal L32p protein family Glyco_trans_1_3 PF13528.1 ABX11947.1 - 9.6e-14 51.2 0.0 4.6e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 1 Alg14 PF08660.6 ABX11947.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like CesA PF11439.3 ABX11947.1 - 0.23 11.3 4.8 0.2 11.6 0.4 2.9 3 0 0 3 3 3 0 Type III secretion system filament chaperone CesA PAPS_reduct PF01507.14 ABX11949.1 - 6.6e-42 143.2 0.0 8.3e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3452 PF11934.3 ABX11949.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) ATP-sulfurylase PF01747.12 ABX11950.1 - 5.2e-86 287.4 0.3 8.8e-86 286.6 0.1 1.4 2 0 0 2 2 2 1 ATP-sulfurylase PUA_2 PF14306.1 ABX11950.1 - 4.5e-47 159.4 0.0 9.2e-47 158.4 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain HhH-GPD PF00730.20 ABX11952.1 - 1.8e-24 86.0 0.4 3e-24 85.3 0.0 1.5 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 ABX11952.1 - 4.1e-08 32.4 0.0 1e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF2400 PF09674.5 ABX11952.1 - 0.00056 19.6 0.1 0.0041 16.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2400) HHH_5 PF14520.1 ABX11952.1 - 0.006 16.7 0.0 0.067 13.3 0.0 2.2 1 1 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 ABX11952.1 - 0.065 13.1 0.0 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF4028 PF13220.1 ABX11952.1 - 0.12 12.0 1.3 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) EndIII_4Fe-2S PF10576.4 ABX11952.1 - 0.74 10.0 4.6 1.4 9.1 3.2 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III DUF521 PF04412.8 ABX11953.1 - 2.8e-100 335.6 0.0 5e-100 334.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF521) Fer4_12 PF13353.1 ABX11953.1 - 0.21 11.6 2.7 0.57 10.3 2.0 1.6 1 1 1 2 2 2 0 4Fe-4S single cluster domain DUF126 PF01989.11 ABX11954.1 - 9e-32 108.6 0.1 1.3e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF126 FbpA PF05833.6 ABX11955.1 - 3e-43 148.0 13.6 3.8e-43 147.6 9.4 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 ABX11955.1 - 1.9e-17 62.9 0.1 6.2e-17 61.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF814) DUF4387 PF14330.1 ABX11955.1 - 0.13 12.5 1.7 4 7.8 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4387) DUF848 PF05852.6 ABX11955.1 - 0.82 9.5 9.9 4.4 7.1 1.7 2.7 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Tweety PF04906.8 ABX11955.1 - 1.6 7.0 8.5 2.8 6.2 0.9 2.2 1 1 0 2 2 2 0 Tweety Ribosomal_S13 PF00416.17 ABX11955.1 - 6.7 7.2 8.5 5 7.6 1.1 3.8 3 1 0 3 3 3 0 Ribosomal protein S13/S18 Rab5ip PF07019.7 ABX11956.1 - 0.0023 18.0 6.2 0.0073 16.4 4.3 1.7 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) 7TM_GPCR_Srsx PF10320.4 ABX11956.1 - 0.003 16.7 2.1 0.0045 16.1 1.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Herpes_UL43 PF05072.8 ABX11956.1 - 0.0087 14.8 0.0 0.01 14.6 0.0 1.0 1 0 0 1 1 1 1 Herpesvirus UL43 protein Trypan_PARP PF05887.6 ABX11956.1 - 0.013 15.3 7.2 0.019 14.8 5.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4396 PF14342.1 ABX11956.1 - 0.053 13.6 1.2 4 7.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) DUF4366 PF14283.1 ABX11956.1 - 0.081 12.3 2.7 0.27 10.6 1.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) PBP1_TM PF14812.1 ABX11956.1 - 0.14 12.4 0.8 0.24 11.7 0.2 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_31 PF13847.1 ABX11957.1 - 1.9e-16 59.9 1.8 3.3e-16 59.2 0.9 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX11957.1 - 8.3e-16 58.5 0.1 1.2e-15 58.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ABX11957.1 - 9.8e-13 48.1 0.4 1.2e-12 47.8 0.3 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 ABX11957.1 - 1.2e-10 41.0 0.4 2.8e-10 39.8 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 ABX11957.1 - 6.4e-10 38.6 2.8 8.4e-10 38.2 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 ABX11957.1 - 9.3e-09 34.7 0.5 1.3e-08 34.2 0.3 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 ABX11957.1 - 2.4e-08 33.7 0.1 5.6e-08 32.5 0.0 1.5 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 ABX11957.1 - 7.4e-08 32.4 0.0 1.4e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ABX11957.1 - 3.7e-07 29.3 0.2 7.8e-07 28.3 0.1 1.6 2 0 0 2 2 2 1 Putative methyltransferase GCD14 PF08704.5 ABX11957.1 - 6.7e-07 29.0 0.0 8.6e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.1 ABX11957.1 - 1.7e-06 28.3 0.0 5.3e-06 26.7 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ABX11957.1 - 1.8e-06 28.3 0.0 4.1e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 ABX11957.1 - 2.4e-06 26.7 0.2 2.9e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 ABX11957.1 - 3e-06 26.5 0.3 6.6e-06 25.4 0.1 1.7 1 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 ABX11957.1 - 5e-06 26.0 0.1 7.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 DUF633 PF04816.7 ABX11957.1 - 3.6e-05 23.2 1.4 5.2e-05 22.6 1.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF633) Methyltransf_12 PF08242.7 ABX11957.1 - 0.0001 22.6 0.1 0.0002 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 ABX11957.1 - 0.00024 20.6 0.2 0.00032 20.2 0.1 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.15 ABX11957.1 - 0.00043 19.3 0.1 0.0006 18.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GidB PF02527.10 ABX11957.1 - 0.0013 17.9 0.4 0.0024 17.0 0.2 1.3 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_24 PF13578.1 ABX11957.1 - 0.0017 19.1 0.0 0.0025 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 ABX11957.1 - 0.0024 17.4 0.1 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein DOT1 PF08123.8 ABX11957.1 - 0.003 16.8 0.4 0.0073 15.6 0.2 1.7 1 1 0 1 1 1 1 Histone methylation protein DOT1 FtsJ PF01728.14 ABX11957.1 - 0.0032 17.4 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 ABX11957.1 - 0.0046 16.6 0.2 0.0066 16.1 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain TRM PF02005.11 ABX11957.1 - 0.0062 15.4 0.0 0.0078 15.1 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase AviRa PF11599.3 ABX11957.1 - 0.007 15.4 0.0 0.0076 15.2 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_5 PF01795.14 ABX11957.1 - 0.0074 15.6 0.0 0.014 14.7 0.0 1.4 1 1 0 1 1 1 1 MraW methylase family N6_Mtase PF02384.11 ABX11957.1 - 0.014 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_23 PF13489.1 ABX11957.1 - 0.017 14.8 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 ABX11957.1 - 0.024 13.6 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CheR PF01739.13 ABX11957.1 - 0.065 12.5 0.1 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain tRNA_U5-meth_tr PF05958.6 ABX11957.1 - 0.12 11.0 0.1 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TP_methylase PF00590.15 ABX11958.1 - 2.6e-50 171.0 0.0 3e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Abhydrolase_2 PF02230.11 ABX11958.1 - 0.046 13.1 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase TP_methylase PF00590.15 ABX11959.1 - 1.7e-44 152.0 0.1 2.1e-44 151.7 0.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.16 ABX11959.1 - 0.0034 17.5 0.3 0.012 15.7 0.2 1.9 1 1 0 1 1 1 1 Radical SAM superfamily DUF2741 PF10890.3 ABX11959.1 - 0.047 13.8 0.1 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) Asp_Glu_race PF01177.17 ABX11960.1 - 1.5e-27 96.9 0.0 1.7e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Snf7 PF03357.16 ABX11961.1 - 0.0015 17.9 9.1 0.0039 16.6 6.3 1.7 1 1 0 1 1 1 1 Snf7 Baculo_PEP_C PF04513.7 ABX11961.1 - 0.022 14.5 2.7 0.6 9.9 0.3 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF694 PF05107.7 ABX11961.1 - 0.033 13.4 0.2 0.044 13.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF694) DUF1110 PF06533.7 ABX11961.1 - 0.25 11.1 2.3 0.31 10.8 0.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1110) CCDC155 PF14662.1 ABX11961.1 - 0.29 10.6 5.5 0.16 11.5 2.0 1.7 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Spc24 PF08286.6 ABX11961.1 - 0.34 10.6 3.3 0.52 10.0 0.2 2.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.7 ABX11961.1 - 1.1 9.5 4.4 14 6.0 0.3 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ALIX_LYPXL_bnd PF13949.1 ABX11961.1 - 1.6 7.5 5.9 8.4 5.2 4.1 2.3 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV Flagellin_C PF00700.16 ABX11961.1 - 1.8 8.7 5.8 4.1 7.6 0.4 2.8 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF745 PF05335.8 ABX11961.1 - 3.9 6.9 9.7 2.4 7.6 1.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF745) PTRF_SDPR PF15237.1 ABX11961.1 - 6.5 6.0 9.6 0.54 9.6 3.3 1.6 2 0 0 2 2 2 0 PTRF/SDPR family Glycos_transf_2 PF00535.21 ABX11962.1 - 1.6e-32 112.5 0.5 3.4e-32 111.4 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 GtrA PF04138.9 ABX11962.1 - 1e-23 83.5 8.5 2.6e-23 82.1 5.9 1.7 1 0 0 1 1 1 1 GtrA-like protein Glyco_tranf_2_3 PF13641.1 ABX11962.1 - 8.9e-08 32.2 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 ABX11962.1 - 1.2e-05 24.5 0.5 1.8e-05 24.0 0.4 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transf_3 PF12804.2 ABX11962.1 - 0.0049 16.9 0.0 0.0073 16.3 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF3784 PF12650.2 ABX11962.1 - 0.029 14.3 1.8 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF1279 PF06916.8 ABX11962.1 - 0.03 14.6 0.2 0.08 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) tRNA-synt_2b PF00587.20 ABX11963.1 - 3e-47 160.4 0.1 7.7e-47 159.0 0.0 1.7 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ABX11963.1 - 4.8e-16 58.4 0.2 1.3e-15 57.1 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain Zn-ribbon_8 PF09723.5 ABX11963.1 - 0.021 14.7 0.4 11 6.0 0.0 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 ABX11963.1 - 0.048 13.2 2.7 2.6 7.7 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ABX11963.1 - 0.11 12.1 2.9 5.6 6.7 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 ABX11963.1 - 0.28 11.5 1.7 16 6.0 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_3 PF14369.1 ABX11963.1 - 0.52 10.3 2.2 4.4 7.3 0.1 2.7 2 0 0 2 2 2 0 zinc-finger AP_endonuc_2 PF01261.19 ABX11964.1 - 2.3e-32 112.0 0.0 4.6e-32 111.0 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DNA_primase_lrg PF04104.9 ABX11965.1 - 2e-26 92.8 0.0 4.7e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DNA_primase_S PF01896.14 ABX11966.1 - 1e-15 57.8 0.3 1.3e-14 54.2 0.2 2.2 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit NRDD PF13597.1 ABX11966.1 - 0.0034 15.5 3.4 0.0041 15.2 1.5 1.7 2 0 0 2 2 2 1 Anaerobic ribonucleoside-triphosphate reductase stn_TNFRSF12A PF12191.3 ABX11966.1 - 0.018 15.0 2.0 0.032 14.2 1.4 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain UPF0182 PF03699.8 ABX11967.1 - 1.3e-29 102.7 15.3 8.4e-28 96.7 10.6 2.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0182) Gifsy-2 PF13856.1 ABX11967.1 - 0.082 13.0 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 ATP-binding sugar transporter from pro-phage DUF1980 PF09323.5 ABX11967.1 - 0.2 11.4 5.9 0.2 11.3 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1980) GATase PF00117.23 ABX11968.1 - 6.7e-23 81.1 0.0 7.9e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ABX11968.1 - 1.9e-09 37.3 0.0 2e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.14 ABX11968.1 - 0.078 12.5 0.1 2 7.9 0.0 2.4 1 1 2 3 3 3 0 SNO glutamine amidotransferase family TPR_11 PF13414.1 ABX11969.1 - 6.5e-22 76.9 9.4 5.2e-14 51.6 1.9 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ABX11969.1 - 1.9e-19 68.3 17.9 1.6e-10 40.1 0.2 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ABX11969.1 - 4.4e-18 63.6 9.2 1.5e-07 30.7 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 ABX11969.1 - 1.1e-14 54.1 3.0 3.1e-08 33.4 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ABX11969.1 - 1.4e-14 53.0 8.0 2.7e-05 23.9 0.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ABX11969.1 - 1e-10 41.9 0.0 0.0078 16.8 0.0 3.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ABX11969.1 - 4.2e-10 38.6 17.6 3.3e-05 23.3 0.1 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 ABX11969.1 - 1.3e-09 37.7 0.0 1.1e-06 28.3 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ABX11969.1 - 1.5e-09 37.6 0.0 0.0051 17.3 0.0 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ABX11969.1 - 8.8e-08 31.3 0.5 5.9e-05 22.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ABX11969.1 - 1.4e-07 31.7 0.4 0.0036 17.6 0.0 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 ABX11969.1 - 3.4e-07 30.2 1.9 2.8 8.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Peptidase_C39_2 PF13529.1 ABX11969.1 - 0.0021 18.4 0.1 0.0071 16.7 0.0 1.9 2 1 0 2 2 2 1 Peptidase_C39 like family TPR_10 PF13374.1 ABX11969.1 - 0.0082 16.0 0.1 0.063 13.2 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ABX11969.1 - 0.01 15.7 1.0 0.093 12.6 0.1 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 ABX11969.1 - 0.018 14.8 3.0 5.9 6.8 0.1 3.4 2 2 1 3 3 3 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ABX11969.1 - 0.019 15.1 6.0 0.19 11.8 4.2 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Caudo_TAP PF02413.12 ABX11969.1 - 0.095 12.8 1.1 0.17 12.0 0.1 2.0 2 1 0 2 2 2 0 Caudovirales tail fibre assembly protein PPTA PF01239.17 ABX11969.1 - 0.34 10.3 3.0 1.1 8.7 0.1 3.2 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat zinc_ribbon_4 PF13717.1 ABX11970.1 - 0.00013 21.5 3.0 0.00059 19.4 2.1 1.9 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 ABX11970.1 - 0.00016 21.1 3.1 0.00058 19.3 2.1 1.8 1 1 0 1 1 1 1 zinc-ribbon domain IBR PF01485.16 ABX11970.1 - 0.0019 18.0 1.1 0.0031 17.3 0.8 1.3 1 0 0 1 1 1 1 IBR domain OrfB_Zn_ribbon PF07282.6 ABX11970.1 - 0.0023 17.5 1.1 0.0033 17.0 0.8 1.2 1 0 0 1 1 1 1 Putative transposase DNA-binding domain CpXC PF14353.1 ABX11970.1 - 0.0044 16.9 2.9 0.0097 15.8 0.0 2.0 1 1 1 2 2 2 1 CpXC protein zf-ribbon_3 PF13248.1 ABX11970.1 - 0.0083 15.3 4.0 0.056 12.6 3.0 1.9 1 1 1 2 2 2 2 zinc-ribbon domain zf-ISL3 PF14690.1 ABX11970.1 - 0.0091 16.0 1.2 0.82 9.7 0.9 2.2 1 1 1 2 2 2 2 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2387 PF09526.5 ABX11970.1 - 0.022 14.6 2.5 0.032 14.1 1.7 1.3 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1 PF03811.8 ABX11970.1 - 0.025 14.0 2.4 0.73 9.3 0.2 2.1 2 0 0 2 2 2 0 InsA N-terminal domain DZR PF12773.2 ABX11970.1 - 0.036 13.8 1.4 0.061 13.1 1.0 1.4 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 ABX11970.1 - 0.038 13.8 0.2 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn_Tnp_IS91 PF14319.1 ABX11970.1 - 0.041 13.3 0.1 0.041 13.3 0.1 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain UPF0547 PF10571.4 ABX11970.1 - 0.041 13.5 8.3 0.17 11.5 5.7 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Ogr_Delta PF04606.7 ABX11970.1 - 0.044 13.4 0.5 6.5 6.4 0.1 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DUF329 PF03884.9 ABX11970.1 - 0.045 13.3 3.5 2.9 7.5 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF329) Prok-RING_1 PF14446.1 ABX11970.1 - 0.047 13.4 2.4 0.061 13.0 1.7 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Ribosomal_S27e PF01667.12 ABX11970.1 - 0.049 13.1 3.1 0.15 11.5 2.2 1.7 1 1 0 1 1 1 0 Ribosomal protein S27 Mu-like_Com PF10122.4 ABX11970.1 - 0.051 12.6 1.3 0.098 11.7 0.9 1.4 1 1 0 1 1 1 0 Mu-like prophage protein Com HypA PF01155.14 ABX11970.1 - 0.054 13.1 0.3 0.056 13.1 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C2H2_4 PF13894.1 ABX11970.1 - 0.14 12.5 0.5 4.7 7.7 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ABX11970.1 - 0.25 11.6 3.6 3.7 7.9 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zinc-ribbons_6 PF07191.7 ABX11970.1 - 0.26 11.1 2.0 0.38 10.5 1.4 1.4 1 1 0 1 1 1 0 zinc-ribbons Auto_anti-p27 PF06677.7 ABX11970.1 - 0.33 10.7 2.0 0.46 10.2 1.4 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF35_N PF12172.3 ABX11970.1 - 0.34 10.8 2.6 10 6.1 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C4_Topoisom PF01396.14 ABX11970.1 - 0.4 10.2 2.5 9.4 5.8 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-H2C2_5 PF13909.1 ABX11970.1 - 0.48 10.7 3.5 0.75 10.1 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-DNL PF05180.7 ABX11970.1 - 0.6 9.8 2.3 8.8 6.1 0.2 2.1 1 1 1 2 2 2 0 DNL zinc finger zinc_ribbon_2 PF13240.1 ABX11970.1 - 0.83 9.2 6.2 3 7.4 4.3 1.9 1 1 0 1 1 1 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 ABX11970.1 - 0.84 9.4 7.2 0.54 10.0 0.4 2.3 2 1 0 2 2 2 0 PhnA Zinc-Ribbon zf-RING_3 PF14369.1 ABX11970.1 - 0.84 9.6 7.1 0.78 9.7 0.5 2.2 1 1 1 2 2 2 0 zinc-finger zf-Di19 PF05605.7 ABX11970.1 - 0.86 9.7 4.2 1.1 9.4 0.4 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 ABX11970.1 - 1.5 8.5 6.9 23 4.6 4.7 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 ABX11970.1 - 2.9 7.9 7.0 73 3.4 4.9 2.1 1 1 0 1 1 1 0 Zinc ribbon domain Ribosomal_S6e PF01092.14 ABX11971.1 - 7.9e-20 70.7 0.2 9.5e-20 70.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S6e GTP_EFTU PF00009.22 ABX11972.1 - 2.7e-40 137.8 0.0 4.5e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 ABX11972.1 - 6e-25 87.1 0.4 2.6e-24 85.0 0.0 2.2 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 ABX11972.1 - 7.7e-05 22.7 0.7 0.00039 20.4 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ABX11972.1 - 0.0008 19.3 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ABX11972.1 - 0.019 14.2 0.1 1.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B NOB1_Zn_bind PF08772.6 ABX11972.1 - 0.029 14.2 0.5 0.078 12.8 0.1 1.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.5 ABX11972.1 - 1.1 9.3 3.1 7.1 6.6 2.4 2.1 1 1 1 2 2 2 0 Zinc ribbon domain Fcf1 PF04900.7 ABX11973.1 - 3.3e-07 30.3 0.0 4.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Fcf1 DUF3842 PF12953.2 ABX11973.1 - 0.0062 16.6 0.1 0.62 10.2 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3842) DUF3919 PF13057.1 ABX11973.1 - 0.01 15.2 1.8 0.012 15.1 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) PIN PF01850.16 ABX11973.1 - 0.032 14.5 0.1 0.046 14.0 0.1 1.3 1 1 0 1 1 1 0 PIN domain Toxin_trans PF07952.7 ABX11973.1 - 0.034 13.0 2.2 0.26 10.1 0.1 2.0 1 1 1 2 2 2 0 Clostridium neurotoxin, Translocation domain PBP PF01161.15 ABX11974.1 - 1.1e-36 125.8 0.0 1.3e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Luciferase_N PF05295.6 ABX11974.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain STT3 PF02516.9 ABX11975.1 - 5.7e-43 147.5 31.1 8.4e-43 147.0 21.5 1.2 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 ABX11975.1 - 2.9e-06 27.2 14.7 2.9e-06 27.2 10.2 3.4 2 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Nop10p PF04135.7 ABX11976.1 - 1.1e-24 85.8 3.1 1.2e-24 85.8 2.1 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family RecR PF02132.10 ABX11976.1 - 0.0015 17.9 1.0 0.0018 17.6 0.7 1.2 1 0 0 1 1 1 1 RecR protein NOB1_Zn_bind PF08772.6 ABX11976.1 - 0.0029 17.4 0.5 0.0031 17.3 0.3 1.2 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF1272 PF06906.6 ABX11976.1 - 0.0054 16.5 0.9 0.006 16.4 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) PolC_DP2 PF03833.8 ABX11976.1 - 0.076 10.6 0.4 0.067 10.8 0.3 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_4 PF14570.1 ABX11976.1 - 0.12 12.0 3.9 0.17 11.5 2.7 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C4H2 PF10146.4 ABX11976.1 - 0.78 9.7 3.1 0.91 9.4 2.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein zf-C2HC_2 PF13913.1 ABX11976.1 - 2.4 7.9 5.6 11 5.7 0.5 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type EIF_2_alpha PF07541.7 ABX11977.1 - 6e-23 80.7 0.3 6e-23 80.7 0.2 1.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 ABX11977.1 - 1.1e-10 41.4 0.0 1.1e-10 41.4 0.0 2.4 3 0 0 3 3 3 1 S1 RNA binding domain MBT PF02820.13 ABX11977.1 - 0.033 14.0 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 mbt repeat EXOSC1 PF10447.4 ABX11977.1 - 0.044 13.7 0.4 0.18 11.7 0.1 2.2 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 CobA_CobO_BtuR PF02572.10 ABX11978.1 - 2.6e-63 212.7 0.3 2.9e-63 212.5 0.2 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_14 PF13173.1 ABX11978.1 - 0.0026 17.6 1.7 0.0075 16.1 1.1 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 ABX11978.1 - 0.024 14.0 1.9 0.23 10.8 0.1 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.18 ABX11978.1 - 0.032 13.6 1.0 0.06 12.7 0.7 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.5 ABX11978.1 - 0.081 12.1 0.1 0.14 11.3 0.1 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 ABX11978.1 - 0.38 10.1 3.5 2.5 7.4 2.5 2.2 1 1 0 1 1 1 0 AAA domain GATase_3 PF07685.9 ABX11979.1 - 8e-33 113.2 0.2 1.3e-32 112.6 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.18 ABX11979.1 - 4.9e-25 88.0 0.3 1.3e-24 86.6 0.0 1.9 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 ABX11979.1 - 9.1e-15 54.7 0.7 2e-12 47.1 0.5 2.4 1 1 0 1 1 1 1 AAA domain SNO PF01174.14 ABX11979.1 - 6.2e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 SNO glutamine amidotransferase family SRP54 PF00448.17 ABX11979.1 - 0.0036 16.7 0.4 0.17 11.2 0.1 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CTP_synth_N PF06418.9 ABX11979.1 - 0.0074 15.4 0.2 0.023 13.8 0.0 1.8 2 0 0 2 2 2 1 CTP synthase N-terminus YhjQ PF06564.7 ABX11979.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein Fer4_NifH PF00142.13 ABX11979.1 - 0.079 12.1 0.7 0.16 11.0 0.1 1.7 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family IstB_IS21 PF01695.12 ABX11979.1 - 0.12 11.8 0.3 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein ArsA_ATPase PF02374.10 ABX11979.1 - 0.12 11.3 1.4 0.17 10.8 0.1 1.9 2 0 0 2 2 2 0 Anion-transporting ATPase CbiC PF02570.10 ABX11980.1 - 2.4e-73 245.7 0.4 2.8e-73 245.5 0.3 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase CbiX PF01903.12 ABX11981.1 - 3.2e-34 117.1 0.0 3.5e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 CbiX CbiK PF06180.6 ABX11981.1 - 5e-07 29.0 0.8 6.1e-07 28.7 0.6 1.1 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Ferrochelatase PF00762.14 ABX11981.1 - 0.0022 17.0 0.0 0.063 12.2 0.0 2.0 1 1 0 1 1 1 1 Ferrochelatase CbiG_N PF11760.3 ABX11982.1 - 3.7e-34 116.2 0.3 6.2e-34 115.5 0.2 1.4 1 0 0 1 1 1 1 Cobalamin synthesis G N-terminal CbiG_C PF01890.11 ABX11982.1 - 1.3e-30 106.1 0.0 2.6e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus CbiG_mid PF11761.3 ABX11982.1 - 2.3e-14 53.3 0.0 1e-13 51.3 0.0 2.0 2 0 0 2 2 2 1 Cobalamin biosynthesis central region SpoU_sub_bind PF08032.7 ABX11982.1 - 0.013 15.6 0.0 0.05 13.7 0.0 2.0 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding zf-H2C2 PF09337.5 ABX11982.1 - 0.048 13.0 0.1 0.92 8.9 0.0 2.4 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger CbiD PF01888.12 ABX11983.1 - 6.1e-88 294.1 5.5 8.1e-88 293.7 3.8 1.1 1 0 0 1 1 1 1 CbiD DUF3042 PF11240.3 ABX11983.1 - 0.034 13.9 1.2 0.49 10.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) NAD_binding_10 PF13460.1 ABX11984.1 - 3.8e-13 49.8 0.0 5.4e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ABX11984.1 - 2.6e-10 39.4 0.1 5e-09 35.2 0.0 2.2 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ABX11984.1 - 6.1e-10 38.9 0.0 4.3e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ABX11984.1 - 1.4e-06 27.4 0.8 0.13 11.2 0.1 4.0 1 1 0 3 3 3 2 Male sterility protein NmrA PF05368.8 ABX11984.1 - 3.7e-06 26.3 1.8 6.6e-06 25.5 1.3 1.4 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 ABX11984.1 - 0.00015 20.7 0.0 0.0023 16.8 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain DUF3394 PF11874.3 ABX11984.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3394) DDE_Tnp_1_3 PF13612.1 ABX11984.1 - 0.017 14.8 0.1 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain S-AdoMet_synt_C PF02773.11 ABX11985.1 - 1.4e-71 238.6 0.0 2.1e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 ABX11985.1 - 2.2e-51 172.8 0.2 3.4e-50 168.9 0.0 2.2 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 ABX11985.1 - 8.1e-41 138.3 1.0 1.2e-40 137.7 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.14 ABX11985.1 - 0.00071 18.1 1.2 0.055 11.9 0.1 2.2 1 1 1 2 2 2 2 S-adenosylmethionine synthetase (AdoMet synthetase) DUF3819 PF12842.2 ABX11985.1 - 0.03 13.9 0.0 0.13 11.9 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3819) LSM PF01423.17 ABX11986.1 - 1.4e-18 66.2 1.5 1.5e-18 66.0 1.1 1.0 1 0 0 1 1 1 1 LSM domain Pox_A31 PF05771.6 ABX11986.1 - 0.047 13.4 0.0 0.057 13.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A31 protein Med15_fungi PF05397.7 ABX11986.1 - 0.1 12.5 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 15 Rad51 PF08423.6 ABX11987.1 - 1.3e-25 89.8 0.1 1.5e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 ABX11987.1 - 3.9e-10 39.4 0.0 5.5e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 ABX11987.1 - 1.3e-09 37.5 6.0 9.6e-09 34.6 0.8 2.2 2 0 0 2 2 2 1 KaiC RecA PF00154.16 ABX11987.1 - 1e-07 31.3 0.1 1.4e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 recA bacterial DNA recombination protein Arch_ATPase PF01637.13 ABX11987.1 - 7.9e-06 25.7 0.9 1.3e-05 25.0 0.3 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_24 PF13479.1 ABX11987.1 - 2.5e-05 23.9 0.3 5.3e-05 22.9 0.2 1.5 1 1 0 1 1 1 1 AAA domain Zot PF05707.7 ABX11987.1 - 2.8e-05 23.6 0.1 3.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) ABC_tran PF00005.22 ABX11987.1 - 0.00027 21.2 1.6 0.00031 21.0 0.8 1.3 1 1 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.12 ABX11987.1 - 0.0013 18.1 0.1 0.0039 16.6 0.1 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_10 PF12846.2 ABX11987.1 - 0.0014 18.0 0.1 0.0033 16.8 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain TrwB_AAD_bind PF10412.4 ABX11987.1 - 0.0035 16.0 0.1 0.0057 15.3 0.1 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 ABX11987.1 - 0.012 15.7 0.7 0.028 14.5 0.5 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 ABX11987.1 - 0.012 14.4 0.1 0.017 13.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 ABX11987.1 - 0.013 15.7 0.8 0.026 14.7 0.5 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 ABX11987.1 - 0.015 14.1 1.9 0.23 10.3 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PhoH PF02562.11 ABX11987.1 - 0.022 13.9 0.0 0.051 12.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 ABX11987.1 - 0.033 13.8 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 ABX11987.1 - 0.05 13.5 1.4 0.091 12.6 1.0 1.6 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 ABX11987.1 - 0.064 13.7 1.6 0.65 10.5 1.1 2.6 1 1 0 1 1 1 0 Miro-like protein CbiA PF01656.18 ABX11987.1 - 0.07 12.5 0.5 0.12 11.7 0.3 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP-synt_ab PF00006.20 ABX11987.1 - 0.083 12.3 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.17 ABX11987.1 - 0.2 11.0 0.8 0.51 9.7 0.6 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF2075 PF09848.4 ABX11987.1 - 0.33 9.8 2.2 2.5 6.9 1.5 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 ABX11988.1 - 3.2e-36 124.3 0.3 1.3e-35 122.3 0.1 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase DEAD_assoc PF08494.6 ABX11988.1 - 5e-35 120.9 0.2 1.4e-34 119.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/H associated Helicase_C PF00271.26 ABX11988.1 - 3.6e-18 65.1 0.1 3.4e-16 58.8 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ABX11988.1 - 1e-08 35.2 0.2 3.2e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 ABX11988.1 - 1.6e-07 30.4 0.1 2.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HypA PF01155.14 ABX11988.1 - 0.021 14.5 0.0 0.063 12.9 0.0 1.8 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Secretin_N_2 PF07655.8 ABX11988.1 - 0.87 10.0 4.7 1.8 8.9 3.3 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain tRNA_anti-codon PF01336.20 ABX11989.1 - 4.8e-11 42.3 0.1 0.0044 16.8 0.0 3.5 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain ABC_tran PF00005.22 ABX11990.1 - 9.9e-29 100.3 0.0 1.7e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ABX11990.1 - 3.2e-13 50.3 4.6 3.3e-12 46.9 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ABX11990.1 - 0.0012 18.3 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 ABX11990.1 - 0.0089 16.3 5.0 0.038 14.3 3.4 2.1 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 ABX11990.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF4162 PF13732.1 ABX11990.1 - 0.017 15.6 1.3 0.017 15.6 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) Mg_chelatase PF01078.16 ABX11990.1 - 0.019 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 ABX11990.1 - 0.083 12.8 1.5 1.9 8.4 0.1 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.14 ABX11990.1 - 0.099 11.8 0.4 10 5.2 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 ABX11990.1 - 0.23 12.2 1.7 0.81 10.5 0.3 2.4 1 1 1 2 2 2 0 AAA domain ABC2_membrane PF01061.19 ABX11991.1 - 5.4e-22 77.9 20.4 8.5e-22 77.3 14.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 ABX11991.1 - 3.2e-14 52.7 33.7 4.3e-14 52.2 16.2 2.0 1 1 1 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 ABX11991.1 - 4.8e-09 35.7 28.8 6.7e-09 35.2 20.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.1 ABX11991.1 - 0.43 9.8 28.3 1.6 7.9 19.6 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3493 PF11998.3 ABX11991.1 - 0.47 10.3 0.0 0.47 10.3 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3493) Oxidored_q2 PF00420.19 ABX11991.1 - 7 6.3 14.8 4.2 7.0 2.9 3.4 2 2 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L UDPG_MGDP_dh_N PF03721.9 ABX11992.1 - 6e-06 25.7 0.1 0.015 14.7 0.0 2.2 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 ABX11992.1 - 0.00039 20.3 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.10 ABX11992.1 - 0.064 13.0 0.0 0.29 10.9 0.0 1.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF354 PF04007.7 ABX11993.1 - 7.7e-50 169.6 7.6 8.7e-50 169.4 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF354) LpxB PF02684.10 ABX11993.1 - 0.00012 20.8 0.6 0.00023 19.9 0.4 1.5 1 1 0 1 1 1 1 Lipid-A-disaccharide synthetase Epimerase_2 PF02350.14 ABX11993.1 - 0.00092 18.0 1.1 0.0021 16.8 0.8 1.5 2 0 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase Glyco_tran_28_C PF04101.11 ABX11993.1 - 0.014 15.0 4.1 0.34 10.5 2.8 2.3 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 ABX11993.1 - 0.019 14.1 0.0 0.056 12.6 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 1 Shikimate_DH PF01488.15 ABX11993.1 - 0.04 14.0 0.1 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2183 PF09949.4 ABX11993.1 - 0.22 11.4 3.2 2.3 8.1 0.3 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) ATP-cone PF03477.11 ABX11993.1 - 0.43 11.0 6.6 4.5 7.7 0.3 2.6 2 0 0 2 2 2 0 ATP cone domain PWI PF01480.12 ABX11993.1 - 3.1 7.9 6.6 1.5 9.0 0.2 2.9 3 0 0 3 3 3 0 PWI domain AAA_23 PF13476.1 ABX11993.1 - 3.2 8.0 15.1 0.84 9.9 7.8 1.8 2 0 0 2 2 2 0 AAA domain NAD_Gly3P_dh_N PF01210.18 ABX11994.1 - 0.041 13.6 0.0 0.14 11.9 0.0 1.9 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MM_CoA_mutase PF01642.17 ABX11994.1 - 0.12 10.5 0.0 0.17 9.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase GrpE PF01025.14 ABX11995.1 - 2.1e-38 131.4 4.7 2.6e-38 131.1 3.3 1.1 1 0 0 1 1 1 1 GrpE NdhM PF10664.4 ABX11995.1 - 0.013 15.3 1.0 0.025 14.4 0.3 1.8 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M DUF4239 PF14023.1 ABX11995.1 - 0.017 14.5 0.3 0.023 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) PK PF00224.16 ABX11995.1 - 0.034 12.7 0.1 0.044 12.3 0.1 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain PARG_cat PF05028.9 ABX11995.1 - 0.039 13.2 0.5 0.28 10.3 0.3 1.8 1 1 0 2 2 2 0 Poly (ADP-ribose) glycohydrolase (PARG) DUF948 PF06103.6 ABX11995.1 - 0.054 13.3 2.2 0.98 9.3 0.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Rgp1 PF08737.5 ABX11995.1 - 0.089 11.8 7.2 0.2 10.6 5.0 1.7 1 1 0 1 1 1 0 Rgp1 Spectrin PF00435.16 ABX11995.1 - 0.093 13.0 3.8 0.15 12.3 1.9 1.8 2 0 0 2 2 2 0 Spectrin repeat Med7 PF05983.6 ABX11995.1 - 0.11 12.2 3.2 5.2 6.8 0.1 2.2 1 1 1 2 2 2 0 MED7 protein UPF0184 PF03670.8 ABX11995.1 - 0.49 10.6 8.4 0.082 13.0 2.8 2.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) NYD-SP28 PF14772.1 ABX11995.1 - 0.93 9.6 6.5 0.35 11.0 2.5 1.8 2 0 0 2 2 2 0 Sperm tail HSP70 PF00012.15 ABX11996.1 - 1.2e-216 720.3 19.9 1e-213 710.6 13.8 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ABX11996.1 - 7.3e-20 70.8 7.0 7.3e-20 70.8 4.9 2.4 2 1 0 2 2 2 1 MreB/Mbl protein Collagen PF01391.13 ABX11996.1 - 2.8e-06 26.7 15.6 5e-06 25.9 10.8 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) FGGY_C PF02782.11 ABX11996.1 - 0.00015 21.4 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RAP1 PF07218.6 ABX11996.1 - 0.1 10.6 6.9 0.18 9.8 4.7 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FtsA PF14450.1 ABX11996.1 - 0.43 10.4 14.8 4.5 7.1 0.1 5.0 3 1 0 3 3 3 0 Cell division protein FtsA CTDII PF01556.13 ABX11997.1 - 8e-28 96.1 6.6 7.3e-23 80.2 0.4 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 ABX11997.1 - 1.7e-26 91.7 1.3 2.6e-26 91.1 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 ABX11997.1 - 2.1e-14 53.2 20.9 4e-14 52.4 14.5 1.5 1 0 0 1 1 1 1 DnaJ central domain NT5C PF06941.7 ABX11998.1 - 3.1e-11 43.1 2.1 3.9e-11 42.8 1.5 1.1 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) GatB_N PF02934.10 ABX11999.1 - 1.7e-76 256.8 0.2 2.7e-76 256.2 0.1 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 ABX11999.1 - 7.1e-21 74.4 9.6 7.1e-21 74.4 6.7 2.3 3 0 0 3 3 3 1 GatB domain YqeY PF09424.5 ABX11999.1 - 0.0022 17.8 0.3 0.0066 16.3 0.2 1.8 1 0 0 1 1 1 1 Yqey-like protein DUF3465 PF11948.3 ABX11999.1 - 0.064 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) Asparaginase PF00710.15 ABX12000.1 - 3.6e-83 279.0 0.1 4.8e-83 278.6 0.0 1.1 1 0 0 1 1 1 1 Asparaginase AAA PF00004.24 ABX12001.1 - 1.9e-99 329.0 0.0 2.6e-49 166.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 ABX12001.1 - 1.3e-28 98.7 0.2 4.6e-28 97.0 0.1 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 ABX12001.1 - 6.1e-16 58.7 0.0 3.7e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 ABX12001.1 - 2e-14 54.0 0.1 3.6e-06 27.0 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 ABX12001.1 - 2.4e-14 52.9 0.0 8.8e-09 34.7 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ABX12001.1 - 4e-13 49.6 0.1 3.9e-05 23.7 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 ABX12001.1 - 2e-11 44.7 0.1 3.4e-05 24.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 ABX12001.1 - 1.4e-10 40.4 0.1 0.00011 21.0 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 ABX12001.1 - 1.7e-10 40.9 0.0 0.0006 19.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 ABX12001.1 - 6.7e-10 38.8 0.8 0.00086 19.0 0.1 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ABX12001.1 - 7.2e-10 38.8 0.0 0.00016 21.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 ABX12001.1 - 2.9e-09 36.3 0.3 6.5e-05 22.1 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin IstB_IS21 PF01695.12 ABX12001.1 - 6.9e-09 35.3 0.3 0.0033 16.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 ABX12001.1 - 1.4e-08 34.7 0.0 0.0043 16.7 0.0 3.7 2 2 1 3 3 3 2 Archaeal ATPase AAA_19 PF13245.1 ABX12001.1 - 3.4e-08 33.1 3.2 0.0051 16.5 0.1 3.6 3 0 0 3 3 3 2 Part of AAA domain CDC48_2 PF02933.12 ABX12001.1 - 7.8e-08 31.8 0.1 1.8e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Sigma54_activat PF00158.21 ABX12001.1 - 1.7e-07 30.8 0.1 0.033 13.6 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 ABX12001.1 - 8.6e-07 29.0 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 ABX12001.1 - 1.3e-06 28.5 0.0 0.037 14.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 ABX12001.1 - 1.5e-06 28.5 0.0 0.021 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 ABX12001.1 - 2.8e-06 26.5 1.2 0.094 11.8 0.0 3.7 3 1 1 4 4 3 2 KaiC NACHT PF05729.7 ABX12001.1 - 5e-06 26.2 0.2 0.45 10.1 0.1 3.9 3 1 0 4 4 4 2 NACHT domain Bac_DnaA PF00308.13 ABX12001.1 - 5.1e-06 26.3 0.0 0.0075 15.9 0.0 2.5 3 0 0 3 3 2 1 Bacterial dnaA protein PhoH PF02562.11 ABX12001.1 - 5.4e-06 25.7 0.3 0.069 12.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Mg_chelatase PF01078.16 ABX12001.1 - 7.9e-06 25.1 1.1 0.033 13.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 ABX12001.1 - 9.4e-06 25.7 0.0 0.1 12.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 ABX12001.1 - 9.6e-06 25.1 6.4 0.61 9.4 0.2 4.2 2 2 1 3 3 3 2 AAA domain AAA_24 PF13479.1 ABX12001.1 - 3.8e-05 23.3 0.2 0.025 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ABX12001.1 - 4.3e-05 22.4 0.0 0.094 11.5 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.22 ABX12001.1 - 5.9e-05 23.3 0.0 0.63 10.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter NTPase_1 PF03266.10 ABX12001.1 - 7.3e-05 22.5 1.8 4.1 7.0 0.0 4.7 3 1 1 4 4 4 0 NTPase DUF815 PF05673.8 ABX12001.1 - 0.00015 20.8 0.0 0.085 11.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 ABX12001.1 - 0.00035 20.1 0.0 0.36 10.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 ABX12001.1 - 0.00056 18.9 0.2 0.31 9.9 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 ABX12001.1 - 0.00081 19.0 0.0 0.81 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 ABX12001.1 - 0.001 18.6 0.0 0.99 8.8 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Parvo_NS1 PF01057.12 ABX12001.1 - 0.0013 17.6 0.1 0.25 10.1 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 ABX12001.1 - 0.0013 18.3 0.1 2 8.0 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 ABX12001.1 - 0.0016 18.3 0.0 0.73 9.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase T2SE PF00437.15 ABX12001.1 - 0.0023 16.9 0.0 1.7 7.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein ResIII PF04851.10 ABX12001.1 - 0.003 17.4 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 ABX12001.1 - 0.0045 16.5 0.0 1.4 8.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain CPT PF07931.7 ABX12001.1 - 0.0077 15.8 0.0 0.85 9.2 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 ABX12001.1 - 0.0089 15.4 0.4 1.4 8.2 0.0 3.2 2 2 0 2 2 2 1 AAA-like domain Guanylate_kin PF00625.16 ABX12001.1 - 0.012 15.1 0.1 7.6 5.9 0.0 3.4 2 1 1 3 3 3 0 Guanylate kinase AFG1_ATPase PF03969.11 ABX12001.1 - 0.017 13.9 0.0 2.7 6.6 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase AAA_29 PF13555.1 ABX12001.1 - 0.021 14.3 0.2 3.9 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 ABX12001.1 - 0.042 13.3 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.4 ABX12001.1 - 0.055 12.9 0.0 17 4.8 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PIF1 PF05970.9 ABX12001.1 - 0.073 12.0 0.0 7.9 5.3 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase KAP_NTPase PF07693.9 ABX12001.1 - 0.084 11.8 0.3 6.5 5.6 0.0 2.9 2 2 1 3 3 3 0 KAP family P-loop domain DUF258 PF03193.11 ABX12001.1 - 0.11 11.7 0.0 7 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 IPT PF01745.11 ABX12001.1 - 0.15 11.2 0.2 10 5.1 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Torsin PF06309.6 ABX12001.1 - 0.17 11.7 0.1 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Torsin Ribosomal_L2_C PF03947.13 ABX12002.1 - 2.2e-33 114.8 1.7 4.6e-33 113.8 1.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 ABX12002.1 - 1.1e-08 34.9 0.0 2.5e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Acylphosphatase PF00708.13 ABX12003.1 - 3.5e-27 94.3 0.3 3.8e-27 94.2 0.2 1.0 1 0 0 1 1 1 1 Acylphosphatase YbjQ_1 PF01906.12 ABX12003.1 - 0.016 15.5 0.0 0.019 15.3 0.0 1.1 1 0 0 1 1 1 0 Putative heavy-metal-binding ATP_bind_3 PF01171.15 ABX12005.1 - 2.4e-20 72.7 0.0 3.8e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 ABX12005.1 - 3.4e-05 22.5 0.0 6.3e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.14 ABX12005.1 - 0.00038 20.3 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.16 ABX12005.1 - 0.03 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase zf-RING_6 PF14835.1 ABX12005.1 - 0.044 13.5 0.6 0.044 13.5 0.4 2.7 3 0 0 3 3 3 0 zf-RING of BARD1-type protein DUF4145 PF13643.1 ABX12005.1 - 0.076 12.8 0.4 0.28 11.0 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) DUF2392 PF10288.4 ABX12005.1 - 0.093 13.0 0.7 0.28 11.5 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2392) C1_1 PF00130.17 ABX12005.1 - 2.2 8.1 16.1 0.25 11.0 2.5 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Methyltransf_23 PF13489.1 ABX12006.1 - 1.4e-20 73.5 0.0 2.3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ABX12006.1 - 9.5e-14 51.6 0.0 1.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ABX12006.1 - 7.6e-11 41.8 0.2 1.3e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ABX12006.1 - 1.1e-09 38.6 0.0 2.5e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX12006.1 - 1.6e-09 38.3 0.0 3.9e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 ABX12006.1 - 3.8e-05 23.1 0.0 0.00016 21.1 0.0 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW DREV PF05219.7 ABX12006.1 - 0.0021 17.0 0.0 0.0034 16.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Elf1 PF05129.8 ABX12006.1 - 0.18 11.4 1.3 0.25 11.0 0.3 1.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-trcl PF13451.1 ABX12006.1 - 0.27 10.8 2.1 0.8 9.3 0.0 2.6 2 0 0 2 2 2 0 Probable zinc-binding domain Peptidase_M50 PF02163.17 ABX12007.1 - 1.8e-24 85.7 0.6 9.8e-24 83.3 0.0 2.3 2 1 0 2 2 2 1 Peptidase family M50 PDZ_2 PF13180.1 ABX12007.1 - 3.1e-10 39.8 0.0 5.9e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 ABX12007.1 - 0.0054 16.8 0.1 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) CutA1 PF03091.10 ABX12008.1 - 1.3e-28 98.6 3.5 1.4e-28 98.5 2.4 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Ribosomal_L18e PF00828.14 ABX12008.1 - 0.027 14.8 0.8 0.054 13.8 0.5 1.5 1 1 1 2 2 2 0 Ribosomal protein L18e/L15 TFIIE_beta PF02186.10 ABX12008.1 - 0.032 14.2 1.0 0.15 12.0 0.2 2.2 1 1 1 2 2 2 0 TFIIE beta subunit core domain DUF692 PF05114.8 ABX12008.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF692) eRF1_1 PF03463.10 ABX12009.1 - 2.1e-19 69.3 0.9 4.7e-19 68.2 0.6 1.6 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 ABX12009.1 - 5e-12 46.2 0.1 1.1e-11 45.1 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 ABX12009.1 - 2.6e-08 34.1 2.0 1e-07 32.1 0.2 2.8 3 1 0 3 3 3 1 eRF1 domain 3 TrkA_C PF02080.16 ABX12009.1 - 0.087 12.4 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 TrkA-C domain UPF0047 PF01894.12 ABX12011.1 - 1.2e-36 125.1 0.0 1.4e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF2387 PF09526.5 ABX12012.1 - 0.0035 17.2 0.7 0.0041 17.0 0.5 1.1 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) Lar_restr_allev PF14354.1 ABX12012.1 - 0.3 11.4 3.1 0.39 11.0 2.2 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar Fe_dep_repr_C PF02742.10 ABX12013.1 - 2.1e-20 72.1 0.7 2.6e-20 71.8 0.0 1.5 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.14 ABX12013.1 - 1.5e-14 53.6 0.3 2.5e-14 52.9 0.2 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_27 PF13463.1 ABX12013.1 - 2.3e-06 27.7 0.0 4.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.17 ABX12013.1 - 3.5e-05 23.4 0.1 5.8e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.2 ABX12013.1 - 6.2e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.1 ABX12013.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.15 ABX12013.1 - 0.00018 21.5 0.2 0.00035 20.6 0.1 1.6 2 0 0 2 2 1 1 Transcriptional regulator TrmB PF01978.14 ABX12013.1 - 0.0005 19.7 0.2 0.00079 19.0 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.1 ABX12013.1 - 0.00095 18.9 0.2 0.0015 18.2 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_1 PF00126.22 ABX12013.1 - 0.0031 17.2 0.0 0.0086 15.7 0.0 1.7 1 1 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.15 ABX12013.1 - 0.0035 16.9 0.1 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.7 ABX12013.1 - 0.0059 16.2 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 HTH domain HTH_6 PF01418.12 ABX12013.1 - 0.038 13.7 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family NLPC_P60 PF00877.14 ABX12013.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 NlpC/P60 family DUF4411 PF14367.1 ABX12013.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) HemN_C PF06969.11 ABX12013.1 - 0.086 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 HemN C-terminal domain HTH_23 PF13384.1 ABX12013.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain IF2_N PF04760.10 ABX12013.1 - 0.17 11.5 0.1 0.17 11.5 0.1 2.4 3 1 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region TrmB PF01978.14 ABX12014.1 - 3.3e-22 77.9 0.1 9.4e-22 76.5 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 ABX12014.1 - 1.5e-07 30.6 0.0 1.8e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_IclR PF09339.5 ABX12014.1 - 5.5e-06 25.8 0.0 8.6e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.1 ABX12014.1 - 6.4e-05 22.2 0.0 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 ABX12014.1 - 0.0047 16.5 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 MarR family Penicillinase_R PF03965.11 ABX12014.1 - 0.0064 16.5 0.1 0.032 14.3 0.0 2.1 2 1 0 2 2 2 1 Penicillinase repressor MarR_2 PF12802.2 ABX12014.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.1 ABX12014.1 - 0.013 15.7 0.0 0.071 13.4 0.0 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain Rrf2 PF02082.15 ABX12014.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_9 PF08221.6 ABX12014.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_34 PF13601.1 ABX12014.1 - 0.063 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain PadR PF03551.9 ABX12014.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PLDc_2 PF13091.1 ABX12014.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 PLD-like domain Radical_SAM PF04055.16 ABX12015.1 - 2.4e-14 53.8 0.2 2.4e-14 53.8 0.1 2.8 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_14 PF13394.1 ABX12015.1 - 2.3e-07 30.8 0.0 2.3e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 ABX12015.1 - 4.7e-07 30.0 0.0 1.6e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 4Fe-4S single cluster domain Glycos_transf_1 PF00534.15 ABX12016.1 - 2.4e-35 121.5 0.3 3.5e-35 120.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ABX12016.1 - 2.7e-20 72.9 0.0 4.9e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 ABX12016.1 - 9.5e-13 48.2 0.0 2.7e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 ABX12016.1 - 7.3e-08 32.7 0.0 0.00081 19.5 0.0 2.2 1 1 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 ABX12016.1 - 1.9e-06 27.7 0.1 4e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.1 ABX12016.1 - 4.6e-05 23.2 0.6 0.00037 20.3 0.4 2.4 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.6 ABX12016.1 - 0.00026 20.5 0.2 0.00064 19.2 0.1 1.8 2 1 0 2 2 2 1 Starch synthase catalytic domain CCT PF06203.9 ABX12016.1 - 0.0097 15.5 0.5 0.02 14.5 0.4 1.5 1 0 0 1 1 1 1 CCT motif Polysacc_synt_2 PF02719.10 ABX12017.1 - 1.6e-94 316.1 1.7 1.8e-94 315.9 1.2 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 ABX12017.1 - 1.2e-23 83.7 0.4 3.3e-22 79.0 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ABX12017.1 - 4.6e-20 71.4 1.6 9.3e-20 70.4 1.1 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ABX12017.1 - 5.2e-18 64.9 0.3 2.1e-16 59.6 0.2 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 ABX12017.1 - 6.2e-10 39.3 0.1 8.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ABX12017.1 - 2.4e-08 34.0 0.0 5.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 ABX12017.1 - 8.7e-08 31.3 3.5 1.3e-06 27.5 1.7 2.7 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.8 ABX12017.1 - 1.2e-06 27.9 1.0 1.8e-06 27.4 0.7 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 ABX12017.1 - 4.8e-05 23.1 0.0 8.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 ABX12017.1 - 0.00064 20.0 1.1 0.0046 17.3 0.0 2.8 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 ABX12017.1 - 0.0058 16.9 0.1 0.37 11.0 0.0 2.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 ABX12017.1 - 0.008 16.0 0.2 0.017 15.0 0.1 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 ABX12017.1 - 0.01 15.8 1.8 0.22 11.5 1.2 2.3 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 ABX12017.1 - 0.021 14.8 0.4 0.063 13.3 0.3 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 ABX12017.1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PMT_2 PF13231.1 ABX12018.1 - 1.4e-09 38.0 31.3 6.2e-09 35.9 10.5 2.7 2 1 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase Polysacc_synt_3 PF13440.1 ABX12019.1 - 6.1e-08 32.4 26.2 6.1e-08 32.4 18.1 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.12 ABX12019.1 - 1.8e-07 30.7 34.9 1.8e-07 30.7 24.2 3.2 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.1 ABX12019.1 - 0.0024 17.6 10.7 0.0024 17.6 7.4 4.2 1 1 3 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Glycos_transf_1 PF00534.15 ABX12020.1 - 3.4e-39 134.0 0.2 5.8e-39 133.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ABX12020.1 - 1.3e-13 51.2 0.0 2.2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 ABX12020.1 - 3.2e-11 43.3 0.0 6.4e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 ABX12020.1 - 6.9e-06 25.9 1.3 6.9e-06 25.9 0.9 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_transf_4 PF13439.1 ABX12020.1 - 3e-05 23.8 0.0 6.2e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 DUF2358 PF10184.4 ABX12020.1 - 0.0068 16.3 3.5 0.0079 16.1 0.3 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2358) Glyco_trans_4_4 PF13579.1 ABX12020.1 - 0.13 12.4 0.0 0.2 11.7 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Epimerase PF01370.16 ABX12021.1 - 3.9e-44 150.8 0.0 4.6e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ABX12021.1 - 1e-29 103.3 0.0 1.2e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 ABX12021.1 - 2.5e-15 56.1 4.6 1.6e-14 53.4 3.2 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 ABX12021.1 - 2.6e-14 52.5 1.9 4.2e-14 51.9 1.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ABX12021.1 - 4e-11 42.3 0.0 4.4e-08 32.3 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 ABX12021.1 - 1.3e-08 35.0 0.0 1.7e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ABX12021.1 - 1.5e-05 25.0 0.0 7.8e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 ABX12021.1 - 0.0036 17.2 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DUF1493 PF07377.7 ABX12021.1 - 0.017 15.1 0.1 0.055 13.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Epimerase PF01370.16 ABX12022.1 - 2.6e-44 151.4 0.0 3e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ABX12022.1 - 9.5e-17 60.7 0.0 1.2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 ABX12022.1 - 4.3e-09 35.4 0.1 8.2e-09 34.5 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ABX12022.1 - 2.3e-07 30.0 0.0 0.0085 15.0 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 ABX12022.1 - 9.4e-06 25.7 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ABX12022.1 - 1.4e-05 25.0 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ABX12022.1 - 5.5e-05 22.2 0.0 0.00018 20.5 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 ABX12022.1 - 0.0015 18.4 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 ABX12022.1 - 0.006 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Peptidase_U57 PF05582.7 ABX12022.1 - 0.079 11.9 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 YabG peptidase U57 Glycos_transf_2 PF00535.21 ABX12023.1 - 1.6e-28 99.4 0.1 2.9e-28 98.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 ABX12023.1 - 4.3e-22 79.0 0.0 5.5e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 ABX12023.1 - 3.4e-08 33.4 0.0 7.1e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 ABX12023.1 - 2.6e-06 26.8 0.0 6e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 ABX12023.1 - 6.4e-06 25.4 1.5 1.2e-05 24.5 1.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.1 ABX12023.1 - 0.00051 19.3 2.0 0.22 10.7 0.1 3.1 1 1 1 2 2 2 2 Glycosyltransferase like family Glyco_tranf_2_4 PF13704.1 ABX12023.1 - 0.00096 19.4 0.0 0.0046 17.2 0.0 2.2 1 1 1 2 2 2 1 Glycosyl transferase family 2 NTP_transferase PF00483.18 ABX12024.1 - 9.4e-57 192.1 0.0 1.3e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 ABX12024.1 - 4.4e-11 43.1 0.0 6.5e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 ABX12024.1 - 2.9e-10 39.1 16.2 1.8e-07 30.3 3.9 3.5 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ABX12024.1 - 1.5e-07 30.8 4.0 1.5e-07 30.8 2.8 2.4 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 ABX12024.1 - 0.0028 16.2 2.7 0.017 13.7 1.8 1.9 1 1 0 1 1 1 1 L-fucokinase Glycos_transf_2 PF00535.21 ABX12024.1 - 0.044 13.4 0.2 0.13 11.9 0.1 1.8 1 1 0 2 2 2 0 Glycosyl transferase family 2 Epimerase PF01370.16 ABX12025.1 - 7.9e-59 198.9 0.0 1e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ABX12025.1 - 3e-18 65.6 0.0 6.2e-18 64.6 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 ABX12025.1 - 1.1e-17 63.7 0.2 1.3e-17 63.4 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ABX12025.1 - 4.5e-16 58.5 0.0 5.6e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 ABX12025.1 - 1.5e-12 47.0 0.1 4.7e-12 45.4 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 ABX12025.1 - 0.0053 16.6 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 ABX12025.1 - 0.018 14.2 0.1 0.065 12.4 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.1 ABX12025.1 - 0.044 13.7 0.0 0.079 12.9 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding Lipase_GDSL_2 PF13472.1 ABX12026.1 - 1.7e-08 34.7 0.0 2.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ABX12026.1 - 3.7e-07 30.2 2.5 3.4e-05 23.8 1.8 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 ABX12026.1 - 0.036 13.8 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family CmcH_NodU PF02543.10 ABX12027.1 - 5.3e-104 348.2 0.0 8e-104 347.6 0.0 1.2 1 0 0 1 1 1 1 Carbamoyltransferase Peptidase_M22 PF00814.20 ABX12027.1 - 3.7e-05 23.3 0.0 0.00067 19.2 0.0 2.2 2 0 0 2 2 2 1 Glycoprotease family Sua5_yciO_yrdC PF01300.13 ABX12027.1 - 0.0078 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination DUF2393 PF09624.5 ABX12030.1 - 0.017 14.6 0.3 0.036 13.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) NeuB PF03102.9 ABX12031.1 - 5.9e-86 287.5 0.0 7.1e-86 287.2 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.7 ABX12031.1 - 0.0088 16.4 0.1 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 SAF domain AP_endonuc_2 PF01261.19 ABX12031.1 - 0.077 12.2 0.0 1.3 8.2 0.0 2.3 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel DAHP_synth_1 PF00793.15 ABX12031.1 - 0.078 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 DAHP synthetase I family DegT_DnrJ_EryC1 PF01041.12 ABX12032.1 - 5.3e-98 328.4 0.0 5.9e-98 328.2 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 ABX12032.1 - 2.3e-08 33.5 0.0 3.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 ABX12032.1 - 6.1e-08 32.0 0.2 9.5e-08 31.3 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 ABX12032.1 - 5.2e-05 21.8 1.0 6.2e-05 21.6 0.7 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Cys_Met_Meta_PP PF01053.15 ABX12032.1 - 0.00016 20.0 0.0 0.00025 19.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.14 ABX12032.1 - 0.00073 18.0 0.1 0.0012 17.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 ABX12032.1 - 0.0018 17.1 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Acetyltransf_7 PF13508.1 ABX12033.1 - 0.01 16.0 0.1 0.021 14.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ABX12033.1 - 0.021 14.6 0.0 0.076 12.8 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain IL34 PF15036.1 ABX12033.1 - 0.051 13.1 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Interleukin 34 Aldolase_2 PF10120.4 ABX12033.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Putative aldolase Formyl_trans_N PF00551.14 ABX12034.1 - 6e-14 51.9 0.0 6.5e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase CTP_transf_3 PF02348.14 ABX12035.1 - 5.7e-26 91.4 1.2 7.7e-26 91.0 0.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.2 ABX12035.1 - 7e-05 22.9 0.0 0.00022 21.3 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain U3snoRNP10 PF12397.3 ABX12035.1 - 0.093 12.6 0.0 0.81 9.6 0.0 2.1 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 GFO_IDH_MocA PF01408.17 ABX12036.1 - 3.1e-18 66.4 0.0 5.5e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.16 ABX12036.1 - 1.6e-06 27.9 1.2 7.9e-06 25.7 0.0 2.2 2 1 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 ABX12036.1 - 1.4e-05 25.2 0.1 5e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 ABX12036.1 - 0.00057 19.2 0.1 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 ABX12036.1 - 0.00059 19.0 0.0 0.0015 17.7 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 ABX12036.1 - 0.00074 19.7 0.4 0.0044 17.2 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.13 ABX12036.1 - 0.0014 18.6 0.0 0.0039 17.1 0.0 1.8 1 1 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 ABX12036.1 - 0.011 14.7 0.2 0.021 13.8 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 ABX12036.1 - 0.012 15.9 0.1 0.059 13.8 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent XkdW PF09636.5 ABX12036.1 - 0.023 14.5 1.4 1.2 9.0 0.2 3.0 3 0 0 3 3 3 0 XkdW protein ApbA PF02558.11 ABX12036.1 - 0.087 12.2 0.1 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF2172 PF09940.4 ABX12037.1 - 2.1e-145 483.9 0.3 2.4e-145 483.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2172) Peptidase_M28 PF04389.12 ABX12037.1 - 4.2e-09 36.3 0.0 7.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 ACPS PF01648.15 ABX12038.1 - 4.3e-19 68.4 0.0 5e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Cyc-maltodext_C PF10438.4 ABX12038.1 - 0.13 12.2 0.3 18 5.4 0.0 2.3 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain Epimerase_2 PF02350.14 ABX12039.1 - 6.2e-08 31.7 0.3 1.2e-07 30.8 0.2 1.4 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Capsule_synth PF05159.9 ABX12039.1 - 2.7e-06 27.0 0.0 4.6e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Capsule polysaccharide biosynthesis protein CW_binding_2 PF04122.7 ABX12039.1 - 0.015 15.4 0.0 0.27 11.4 0.0 3.1 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 B5 PF03484.10 ABX12039.1 - 0.33 10.8 3.0 0.52 10.1 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetase B5 domain Toxin_64 PF15542.1 ABX12039.1 - 0.78 10.3 0.1 0.78 10.3 0.0 5.3 5 2 1 6 6 6 0 Putative toxin 64 HMGL-like PF00682.14 ABX12040.1 - 1.5e-31 109.8 0.0 2.5e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 HMGL-like DmpG_comm PF07836.6 ABX12040.1 - 3.1e-06 26.4 0.0 8.2e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 DmpG-like communication domain AMP-binding PF00501.23 ABX12041.1 - 1.6e-55 188.2 0.0 2e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ABX12041.1 - 0.00037 21.3 0.0 0.00061 20.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cyclase PF04199.8 ABX12042.1 - 1.1e-37 129.4 0.0 1.4e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase PP-binding PF00550.20 ABX12043.1 - 0.00086 19.5 0.2 0.002 18.3 0.1 1.6 1 1 0 1 1 1 1 Phosphopantetheine attachment site KilA-N PF04383.8 ABX12043.1 - 0.067 12.8 0.2 0.082 12.5 0.2 1.3 1 0 0 1 1 1 0 KilA-N domain Antibiotic_NAT PF02522.9 ABX12044.1 - 2.2e-29 102.3 0.0 2.5e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Aminoglycoside 3-N-acetyltransferase FdtA PF05523.6 ABX12045.1 - 1.3e-26 92.6 0.1 1.4e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 WxcM-like, C-terminal Cupin_1 PF00190.17 ABX12045.1 - 0.00036 19.9 0.0 0.00047 19.6 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 ABX12045.1 - 0.00056 19.3 0.0 0.0019 17.6 0.0 1.8 1 1 0 1 1 1 1 Cupin domain Polysacc_synt_2 PF02719.10 ABX12046.1 - 2.7e-97 325.2 0.1 3.5e-97 324.8 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 ABX12046.1 - 2.9e-28 98.9 0.0 3.8e-27 95.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ABX12046.1 - 1.4e-24 86.2 0.0 7e-21 74.1 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ABX12046.1 - 3.6e-16 58.8 0.0 2e-14 53.1 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 ABX12046.1 - 1.1e-11 45.0 0.0 1.6e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 ABX12046.1 - 1.4e-11 43.8 2.0 2.2e-08 33.3 0.8 2.9 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.20 ABX12046.1 - 1.1e-10 41.6 0.0 1.6e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 ABX12046.1 - 8.8e-10 38.2 1.0 1.2e-09 37.7 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 ABX12046.1 - 2.3e-07 30.6 0.0 3.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 ABX12046.1 - 0.0047 15.9 0.0 0.0076 15.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 ABX12046.1 - 0.0073 16.7 0.0 0.033 14.6 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 ABX12046.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 ABX12046.1 - 0.017 15.0 0.0 0.06 13.3 0.0 2.0 2 1 0 2 2 2 0 TrkA-N domain ThiF PF00899.16 ABX12046.1 - 0.041 13.6 0.1 0.34 10.7 0.0 2.3 1 1 1 2 2 2 0 ThiF family Epimerase_2 PF02350.14 ABX12047.1 - 1e-06 27.8 0.2 2.4e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase GARS_N PF02844.10 ABX12047.1 - 0.1 13.0 0.2 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Aminotran_3 PF00202.16 ABX12048.1 - 6.7e-41 140.2 0.0 1.1e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III LigB PF02900.13 ABX12048.1 - 0.004 16.1 0.0 0.0065 15.4 0.0 1.3 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase CTP_transf_3 PF02348.14 ABX12049.1 - 3.3e-12 46.5 0.8 4.4e-12 46.1 0.6 1.2 1 0 0 1 1 1 1 Cytidylyltransferase GSP_synth PF03738.9 ABX12049.1 - 0.065 13.4 0.1 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Glutathionylspermidine synthase preATP-grasp Epimerase PF01370.16 ABX12050.1 - 7.9e-56 189.1 0.0 9.7e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ABX12050.1 - 1.8e-09 36.8 0.0 2.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase_Csub PF13950.1 ABX12050.1 - 3.6e-05 23.6 0.0 7.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NmrA PF05368.8 ABX12050.1 - 7.1e-05 22.1 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 ABX12050.1 - 0.052 13.4 0.0 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase SRP1_TIP1 PF00660.12 ABX12050.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Seripauperin and TIP1 family GFO_IDH_MocA PF01408.17 ABX12051.1 - 1.1e-07 32.3 0.0 2.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.14 ABX12051.1 - 0.0048 16.0 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phage_holin_1 PF04531.8 ABX12051.1 - 0.033 14.2 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin F420_oxidored PF03807.12 ABX12051.1 - 0.093 13.1 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SapC PF07277.6 ABX12051.1 - 0.093 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 SapC Sulfatase PF00884.18 ABX12052.1 - 1.4e-32 113.0 0.0 2.4e-31 109.0 0.0 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ABX12052.1 - 4.1e-13 49.3 0.1 2.1e-07 30.6 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 ABX12052.1 - 0.0048 16.3 0.0 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase_C PF14707.1 ABX12052.1 - 0.0077 16.5 0.2 0.018 15.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase HTH_3 PF01381.17 ABX12053.1 - 1.2e-11 44.2 0.1 1e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix HTH_19 PF12844.2 ABX12053.1 - 3.7e-07 30.0 0.8 0.0036 17.3 0.0 2.7 3 0 0 3 3 3 2 Helix-turn-helix domain Cupin_2 PF07883.6 ABX12053.1 - 3.7e-06 26.3 0.2 0.085 12.3 0.0 2.7 2 1 0 2 2 2 2 Cupin domain HTH_31 PF13560.1 ABX12053.1 - 2.6e-05 24.3 0.0 0.02 15.0 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_26 PF13443.1 ABX12053.1 - 7.4e-05 22.8 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Sulfatase PF00884.18 ABX12054.1 - 1.6e-21 76.7 1.2 2e-20 73.1 0.9 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ABX12054.1 - 5.7e-07 29.1 2.7 0.00042 19.7 0.1 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 ABX12054.1 - 0.0001 20.8 0.4 0.00013 20.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DIOX_N PF14226.1 ABX12054.1 - 0.05 14.1 0.1 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal NTP_transf_3 PF12804.2 ABX12055.1 - 7.2e-13 48.9 0.0 1.2e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 ABX12055.1 - 1.5e-07 31.2 0.0 2.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transferase PF00483.18 ABX12055.1 - 6.1e-06 25.7 0.3 1.9e-05 24.0 0.1 1.9 2 1 0 2 2 2 1 Nucleotidyl transferase PEP_mutase PF13714.1 ABX12056.1 - 1.4e-68 230.6 0.3 1.7e-68 230.3 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 ABX12056.1 - 1.4e-07 30.1 0.0 4.2e-07 28.5 0.0 1.7 1 1 0 1 1 1 1 Isocitrate lyase family Dus PF01207.12 ABX12056.1 - 0.033 13.0 0.3 6.9 5.3 0.0 2.8 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) Pantoate_transf PF02548.10 ABX12056.1 - 0.038 13.1 0.6 0.67 9.0 0.0 2.5 3 0 0 3 3 3 0 Ketopantoate hydroxymethyltransferase Fe-ADH PF00465.14 ABX12057.1 - 1.4e-52 178.6 0.0 3.7e-52 177.1 0.0 1.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 ABX12057.1 - 3e-16 59.4 0.0 4e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 ABX12057.1 - 0.00067 18.6 0.0 0.12 11.2 0.0 2.3 2 0 0 2 2 2 2 3-dehydroquinate synthase Rieske PF00355.21 ABX12058.1 - 2.1e-14 52.8 0.0 2.4e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 ABX12058.1 - 2.3e-06 27.2 0.0 2.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Lactamase_B_3 PF13483.1 ABX12059.1 - 1.2e-14 54.4 0.0 2.1e-14 53.5 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 ABX12059.1 - 6.5e-07 29.0 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ABX12059.1 - 2.4e-06 27.3 0.0 3.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CBS PF00571.23 ABX12060.1 - 1.1e-24 85.8 0.3 3.9e-06 26.5 0.1 4.2 4 0 0 4 4 4 4 CBS domain Nexin_C PF08628.7 ABX12060.1 - 0.034 14.2 0.1 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 Sorting nexin C terminal Glycos_transf_2 PF00535.21 ABX12061.1 - 5e-27 94.6 0.3 6.8e-27 94.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 ABX12061.1 - 0.00021 21.1 0.0 0.00029 20.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 ABX12061.1 - 0.0036 17.5 0.0 0.0064 16.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 NTP_transf_3 PF12804.2 ABX12061.1 - 0.066 13.2 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF4293 PF14126.1 ABX12061.1 - 0.13 12.1 2.6 0.29 11.0 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Glyco_transf_21 PF13506.1 ABX12061.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Sulfotransfer_1 PF00685.22 ABX12062.1 - 1.6e-17 63.6 1.0 2.1e-17 63.2 0.7 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 ABX12062.1 - 2.3e-07 31.8 0.0 9.3e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.9 ABX12062.1 - 0.012 15.2 0.1 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 Sulfotransferase family SRPRB PF09439.5 ABX12062.1 - 0.038 13.1 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit bact-PGI_C PF10432.4 ABX12063.1 - 3.6e-44 150.2 0.1 5.3e-44 149.6 0.1 1.3 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal region SIS PF01380.17 ABX12063.1 - 9.5e-10 38.1 0.8 3.1e-09 36.5 0.0 2.3 3 1 1 4 4 4 1 SIS domain SIS_2 PF13580.1 ABX12063.1 - 0.0021 17.7 0.2 0.0077 15.9 0.0 2.0 2 0 0 2 2 2 1 SIS domain FolB PF02152.13 ABX12063.1 - 0.078 13.1 0.3 7.1 6.8 0.0 3.3 3 1 0 3 3 3 0 Dihydroneopterin aldolase Epimerase PF01370.16 ABX12064.1 - 3.1e-59 200.2 0.0 3.7e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ABX12064.1 - 6.3e-25 87.4 0.0 1e-24 86.7 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ABX12064.1 - 1.4e-23 83.2 0.1 8.7e-23 80.6 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 ABX12064.1 - 3.2e-20 72.1 0.0 4.1e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 ABX12064.1 - 1.1e-12 47.4 0.1 6.3e-11 41.6 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 ABX12064.1 - 1.1e-09 38.5 0.0 2.8e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 ABX12064.1 - 7.1e-09 35.2 0.1 2.2e-08 33.6 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 ABX12064.1 - 9.9e-06 25.5 0.0 2.5e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ABX12064.1 - 5e-05 23.0 0.0 0.00016 21.4 0.0 1.8 1 1 0 1 1 1 1 KR domain DapB_N PF01113.15 ABX12064.1 - 0.0004 20.2 0.0 0.0011 18.8 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase_Csub PF13950.1 ABX12064.1 - 0.0068 16.3 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit TrkA_N PF02254.13 ABX12064.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Beta-lactamase2 PF13354.1 ABX12064.1 - 0.027 13.9 0.1 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family IF-2B PF01008.12 ABX12065.1 - 6.3e-85 284.5 1.7 7.7e-85 284.2 1.2 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Serine_rich PF08824.5 ABX12065.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF1024 PF06260.7 ABX12065.1 - 0.041 14.0 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) RRM_1 PF00076.17 ABX12065.1 - 0.045 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GFO_IDH_MocA PF01408.17 ABX12066.1 - 4.8e-07 30.3 0.0 8.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.1 ABX12066.1 - 2e-05 24.8 0.0 9.7e-05 22.5 0.0 2.2 1 1 1 2 2 2 1 Putative NAD(P)-binding ThiF PF00899.16 ABX12066.1 - 7.6e-05 22.5 0.7 0.00016 21.4 0.0 2.1 2 1 0 2 2 2 1 ThiF family ApbA PF02558.11 ABX12066.1 - 0.0025 17.2 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 ABX12066.1 - 0.0039 17.1 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_18 PF12847.2 ABX12066.1 - 0.0079 16.7 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ABX12066.1 - 0.0089 16.4 0.1 0.03 14.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ABX12066.1 - 0.02 15.2 0.0 0.063 13.6 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Semialdhyde_dh PF01118.19 ABX12066.1 - 0.024 14.9 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FAM91_C PF14648.1 ABX12066.1 - 0.026 13.3 0.1 0.041 12.7 0.1 1.2 1 0 0 1 1 1 0 FAM91 C-terminus Methyltransf_11 PF08241.7 ABX12066.1 - 0.055 13.9 0.0 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.13 ABX12066.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 ABX12067.1 - 7.3e-10 39.4 0.0 1.3e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF59 PF01883.14 ABX12068.1 - 2.5e-16 59.4 0.2 6.5e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF59 PqqD PF05402.7 ABX12068.1 - 1.9e-08 34.1 0.0 3.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) HemN_C PF06969.11 ABX12068.1 - 0.077 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 HemN C-terminal domain adh_short_C2 PF13561.1 ABX12069.1 - 3.1e-11 43.5 0.0 3.8e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ABX12069.1 - 6.7e-06 26.1 0.0 0.0077 16.1 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase RmlD_sub_bind PF04321.12 ABX12069.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 ABX12069.1 - 0.029 13.7 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUSP PF06337.7 ABX12069.1 - 0.13 12.6 0.2 7.8 6.9 0.0 2.3 2 0 0 2 2 2 0 DUSP domain Glyco_hydro_47 PF01532.15 ABX12070.1 - 0.099 11.2 0.0 0.1 11.2 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 DUF998 PF06197.8 ABX12071.1 - 0.0012 18.1 3.8 0.002 17.4 2.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF998) DUF2231 PF09990.4 ABX12071.1 - 0.01 16.1 5.7 1.1 9.5 0.6 2.3 1 1 1 2 2 2 2 Predicted membrane protein (DUF2231) Tetraspannin PF00335.15 ABX12071.1 - 0.14 11.3 13.5 0.039 13.2 2.8 2.5 2 1 0 2 2 2 0 Tetraspanin family Afaf PF15339.1 ABX12071.1 - 0.18 11.3 0.4 0.27 10.7 0.3 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor DUF2104 PF09877.4 ABX12071.1 - 0.98 9.4 7.3 1.1 9.3 0.4 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2104) BPD_transp_1 PF00528.17 ABX12071.1 - 1.3 8.4 8.2 0.16 11.4 0.7 2.6 2 1 0 3 3 3 0 Binding-protein-dependent transport system inner membrane component DUF973 PF06157.6 ABX12072.1 - 0.17 10.8 6.0 0.49 9.3 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF3244 PF11589.3 ABX12072.1 - 1.1 9.0 4.8 1.1 8.9 0.3 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3244) DUF4064 PF13273.1 ABX12072.1 - 1.1 9.4 5.3 3.7 7.7 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Aminotran_1_2 PF00155.16 ABX12073.1 - 1.5e-59 201.8 0.0 1.8e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 ABX12073.1 - 2.8e-08 32.9 0.0 4.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 ABX12073.1 - 4.9e-08 32.4 0.0 7.9e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 ABX12073.1 - 0.0017 16.7 0.0 0.0026 16.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 ABX12073.1 - 0.0021 17.2 0.0 0.0035 16.5 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.2 ABX12073.1 - 0.022 13.3 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase HRDC PF00570.18 ABX12073.1 - 0.15 11.8 0.0 39 4.0 0.0 3.2 4 0 0 4 4 4 0 HRDC domain Pyridox_oxidase PF01243.15 ABX12074.1 - 1.1e-16 60.6 0.0 1.6e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 ABX12074.1 - 2.5e-11 43.5 0.0 3.1e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF308 PF03729.8 ABX12075.1 - 0.0019 18.1 0.4 1.3 9.0 0.0 2.2 2 0 0 2 2 2 2 Short repeat of unknown function (DUF308) MerC PF03203.9 ABX12075.1 - 0.0048 17.2 0.2 0.012 15.9 0.1 1.6 1 1 1 2 2 2 1 MerC mercury resistance protein DUF1084 PF06454.6 ABX12075.1 - 0.098 11.6 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) YfzA PF14118.1 ABX12075.1 - 0.11 12.6 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 YfzA-like protein Gram_pos_anchor PF00746.16 ABX12075.1 - 0.11 12.2 1.3 3.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Gram positive anchor DctQ PF04290.7 ABX12075.1 - 0.18 11.5 2.4 0.71 9.6 1.8 1.7 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component VPEP PF07589.6 ABX12075.1 - 0.89 9.5 5.3 0.3 11.0 1.3 1.9 2 0 0 2 2 2 0 PEP-CTERM motif F420_oxidored PF03807.12 ABX12076.1 - 6.5e-16 58.5 0.0 1.2e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 ABX12076.1 - 0.031 13.7 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 ABX12076.1 - 0.033 14.0 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.15 ABX12076.1 - 0.049 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 ABX12076.1 - 0.07 13.1 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 ABX12076.1 - 0.082 12.6 0.2 0.14 11.9 0.2 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus His_Phos_1 PF00300.17 ABX12077.1 - 1e-35 123.1 0.0 1.2e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lipase_GDSL_3 PF14606.1 ABX12077.1 - 0.045 13.4 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF2391 PF09622.5 ABX12078.1 - 0.049 12.7 0.1 0.052 12.7 0.1 1.0 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) MFS_1 PF07690.11 ABX12078.1 - 0.051 12.2 0.6 0.06 12.0 0.4 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily TatC PF00902.13 ABX12078.1 - 1.6 8.0 4.5 4 6.7 3.1 1.7 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) COX2 PF00116.15 ABX12079.1 - 3.9e-20 71.8 1.7 1e-17 64.1 1.2 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.1 ABX12079.1 - 2.6e-06 27.2 0.0 3e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 Cupredoxin-like domain COX1 PF00115.15 ABX12080.1 - 2.7e-140 467.9 60.4 3.5e-140 467.5 41.9 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Copper-bind PF00127.15 ABX12081.1 - 5e-13 49.1 0.1 4.3e-06 26.8 0.0 2.7 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 ABX12081.1 - 1.9e-06 27.6 0.0 4.2e-05 23.3 0.0 2.8 3 1 0 3 3 3 1 Cupredoxin-like domain Cu-oxidase_3 PF07732.10 ABX12081.1 - 0.00018 21.2 0.3 0.0006 19.5 0.1 2.0 2 1 0 2 2 2 1 Multicopper oxidase Cu_bind_like PF02298.12 ABX12081.1 - 0.084 12.6 0.1 0.44 10.3 0.1 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain Cu-oxidase_2 PF07731.9 ABX12081.1 - 0.12 11.9 0.0 1 8.8 0.0 2.5 4 0 0 4 4 4 0 Multicopper oxidase Rhodopsin_N PF10413.4 ABX12081.1 - 5.6 6.7 7.2 22 4.8 0.2 3.4 4 0 0 4 4 4 0 Amino terminal of the G-protein receptor rhodopsin COX15-CtaA PF02628.10 ABX12082.1 - 3.5e-26 91.8 7.4 4.5e-26 91.4 5.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF998 PF06197.8 ABX12082.1 - 0.0044 16.3 5.2 0.0044 16.3 3.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF998) DUF4418 PF14387.1 ABX12082.1 - 0.05 13.3 0.4 0.05 13.3 0.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4418) PseudoU_synth_2 PF00849.17 ABX12082.1 - 0.08 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA pseudouridylate synthase SHP PF03579.8 ABX12082.1 - 0.89 8.9 4.4 0.28 10.5 0.3 2.2 1 1 1 2 2 2 0 Small hydrophobic protein Cytochrom_B561 PF03188.11 ABX12082.1 - 1.2 8.9 8.3 6.3 6.6 5.7 2.0 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 AHSA1 PF08327.6 ABX12084.1 - 6.6e-08 32.7 0.1 1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 ABX12084.1 - 8.5e-08 32.4 0.0 1.1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 ABX12084.1 - 9.8e-08 32.0 0.0 1.5e-07 31.5 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HATPase_c PF02518.21 ABX12085.1 - 4.2e-21 74.7 0.0 7.4e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ABX12085.1 - 1.5e-09 37.6 0.0 3.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 ABX12085.1 - 3e-06 26.8 0.0 6.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 ABX12085.1 - 0.00016 21.3 0.1 0.00048 19.7 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 ABX12085.1 - 0.0077 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain IncA PF04156.9 ABX12085.1 - 0.94 9.0 7.3 3.8 7.0 5.0 2.2 1 1 0 1 1 1 0 IncA protein DUF4231 PF14015.1 ABX12085.1 - 1.4 8.9 15.5 0.65 10.0 0.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) Methyltransf_11 PF08241.7 ABX12086.1 - 1.3e-16 60.7 0.0 2.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ABX12086.1 - 8.3e-16 58.2 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ABX12086.1 - 4e-14 52.4 0.1 5.2e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ABX12086.1 - 2.3e-08 34.4 0.0 4.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ABX12086.1 - 4.7e-08 33.0 0.0 7.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ABX12086.1 - 2.6e-07 29.9 0.0 3.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 ABX12086.1 - 9.6e-07 28.6 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX12086.1 - 1.4e-06 28.8 0.0 1.9e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ABX12086.1 - 0.0089 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 ABX12086.1 - 0.073 12.4 0.0 0.12 11.6 0.0 1.3 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Ribosomal_L18_c PF14204.1 ABX12086.1 - 0.14 12.6 2.0 17 6.0 0.0 2.5 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region KRBA1 PF15287.1 ABX12087.1 - 0.051 12.9 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 KRBA1 family repeat Aminotran_4 PF01063.14 ABX12088.1 - 9.6e-44 149.5 0.0 1.1e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV AA_kinase PF00696.23 ABX12089.1 - 6.2e-29 101.2 1.4 1.3e-28 100.1 0.3 1.9 2 1 0 2 2 2 1 Amino acid kinase family PASTA PF03793.14 ABX12089.1 - 0.033 13.8 0.1 1.4 8.6 0.0 2.7 2 0 0 2 2 2 0 PASTA domain ACT PF01842.20 ABX12089.1 - 0.12 11.8 0.8 0.56 9.7 0.6 2.2 1 0 0 1 1 1 0 ACT domain Glyco_trans_1_3 PF13528.1 ABX12090.1 - 3.9e-16 59.1 0.0 5.2e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 ABX12090.1 - 1e-14 54.5 0.8 4.2e-14 52.5 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.1 ABX12090.1 - 0.00048 20.2 0.0 0.0013 18.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 APP_amyloid PF10515.4 ABX12091.1 - 0.093 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 beta-amyloid precursor protein C-terminus Sir1 PF11603.3 ABX12093.1 - 0.1 12.7 0.3 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 Regulatory protein Sir1 Ammonium_transp PF00909.16 ABX12094.1 - 0.0027 16.2 7.7 0.0027 16.2 5.3 1.8 1 1 2 3 3 3 1 Ammonium Transporter Family Bacteriocin_IIc PF10439.4 ABX12094.1 - 1.7 8.8 4.9 1.1 9.4 0.8 2.3 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Nuc_rec_co-act PF08815.5 ABX12095.1 - 0.048 13.1 0.1 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear receptor coactivator Radical_SAM PF04055.16 ABX12097.1 - 1.3e-15 57.9 0.2 4.7e-15 56.1 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 ABX12097.1 - 0.00026 21.0 0.1 0.001 19.1 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain IMPDH PF00478.20 ABX12097.1 - 0.023 13.6 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain HTH_5 PF01022.15 ABX12098.1 - 2.8e-11 42.8 0.4 4.4e-11 42.2 0.1 1.4 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 ABX12098.1 - 1.4e-07 30.8 1.2 2e-07 30.2 0.8 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 ABX12098.1 - 2.2e-07 30.5 0.0 3.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain B-block_TFIIIC PF04182.7 ABX12098.1 - 1.9e-06 27.6 0.1 2.6e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_11 PF08279.7 ABX12098.1 - 0.00018 21.0 0.1 0.00027 20.5 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_45 PF14947.1 ABX12098.1 - 0.00027 20.6 1.0 0.00042 20.0 0.7 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.14 ABX12098.1 - 0.00042 19.9 0.0 0.00073 19.2 0.0 1.4 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.1 ABX12098.1 - 0.00095 18.9 0.0 0.0074 16.0 0.0 2.0 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.2 ABX12098.1 - 0.002 17.7 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_12 PF08461.5 ABX12098.1 - 0.002 17.8 0.1 0.0032 17.1 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_34 PF13601.1 ABX12098.1 - 0.002 18.1 0.3 0.0035 17.3 0.1 1.5 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR PF01047.17 ABX12098.1 - 0.0023 17.6 0.1 0.0035 16.9 0.1 1.3 1 0 0 1 1 1 1 MarR family DUF4423 PF14394.1 ABX12098.1 - 0.0094 15.5 0.9 0.079 12.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) Rrf2 PF02082.15 ABX12098.1 - 0.054 13.6 0.2 0.096 12.8 0.1 1.4 1 1 0 1 1 1 0 Transcriptional regulator Phage_rep_org_N PF09681.5 ABX12098.1 - 0.062 12.8 0.1 0.062 12.8 0.1 1.1 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) Phage_rep_O PF04492.8 ABX12098.1 - 0.073 13.2 0.0 0.092 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage replication protein O HTH_28 PF13518.1 ABX12098.1 - 0.084 12.8 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Pox_E10 PF04805.7 ABX12098.1 - 0.11 12.0 0.3 0.19 11.3 0.2 1.3 1 0 0 1 1 1 0 E10-like protein conserved region DUF2999 PF11212.3 ABX12098.1 - 0.11 12.5 0.1 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2999) FaeA PF04703.7 ABX12098.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 FaeA-like protein HTH_29 PF13551.1 ABX12098.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix Flavi_NS2B PF01002.14 ABX12099.1 - 0.065 12.8 1.4 0.1 12.1 1.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B SHR3_chaperone PF08229.6 ABX12099.1 - 1.5 7.7 4.6 2 7.3 3.2 1.3 1 1 0 1 1 1 0 ER membrane protein SH3 DUF443 PF04276.7 ABX12100.1 - 0.0026 17.2 4.8 0.0036 16.7 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF443) DUF3493 PF11998.3 ABX12100.1 - 0.021 14.7 1.0 0.044 13.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) DUF3278 PF11683.3 ABX12100.1 - 0.17 11.9 3.9 0.072 13.0 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) DUF3270 PF11674.3 ABX12100.1 - 0.31 11.0 2.0 14 5.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3270) RNase_H PF00075.19 ABX12101.1 - 4e-16 59.5 0.0 4.6e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 ABX12101.1 - 3.6e-11 42.6 0.1 4.9e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like Hex_IIIa PF02455.11 ABX12101.1 - 0.063 11.9 0.0 0.078 11.6 0.0 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) ATP-grasp_5 PF13549.1 ABX12102.1 - 2.1e-79 265.8 1.0 4.6e-79 264.7 0.7 1.6 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 ABX12102.1 - 4.3e-52 175.3 1.6 7.9e-52 174.5 0.5 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 ABX12102.1 - 8.7e-24 83.9 1.5 2.2e-23 82.6 0.1 2.5 3 0 0 3 3 3 1 CoA binding domain CoA_binding PF02629.14 ABX12102.1 - 2.2e-10 40.8 3.4 1.6e-09 38.1 0.6 2.9 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.5 ABX12102.1 - 1.1e-05 24.9 1.8 3e-05 23.5 1.2 1.9 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 ABX12102.1 - 3.3e-05 23.7 0.0 0.00011 21.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 ABX12102.1 - 0.00068 18.9 0.3 0.0016 17.8 0.2 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 ABX12102.1 - 0.029 13.7 0.5 0.23 10.7 0.2 2.4 1 1 0 1 1 1 0 ATP-grasp domain BLUF PF04940.7 ABX12102.1 - 0.15 11.8 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 Sensors of blue-light using FAD HpaB_N PF11794.3 ABX12103.1 - 5e-88 294.9 0.0 1.3e-87 293.5 0.0 1.6 2 0 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.8 ABX12103.1 - 4.3e-74 247.7 0.1 5.7e-74 247.4 0.0 1.1 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Peptidase_S24 PF00717.18 ABX12104.1 - 5.8e-08 32.2 0.6 2.1e-07 30.4 0.1 2.1 2 0 0 2 2 2 1 Peptidase S24-like MscL PF01741.13 ABX12104.1 - 0.06 13.4 0.0 0.06 13.4 0.0 2.1 3 0 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL DUF1510 PF07423.6 ABX12104.1 - 0.51 9.6 13.1 0.061 12.6 5.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DZR PF12773.2 ABX12105.1 - 3.2e-07 30.0 9.2 0.00012 21.8 1.9 2.4 2 0 0 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.1 ABX12105.1 - 6.7e-06 25.1 5.8 6.7e-06 25.1 4.0 2.4 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 ABX12105.1 - 4.9e-05 22.6 6.3 4.9e-05 22.6 4.4 2.2 3 0 0 3 3 3 1 zinc-ribbon domain PRC PF05239.11 ABX12105.1 - 0.00023 20.9 0.1 0.00041 20.1 0.1 1.4 1 0 0 1 1 1 1 PRC-barrel domain DUF3279 PF11682.3 ABX12105.1 - 0.059 12.9 0.9 16 5.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3279) A2L_zn_ribbon PF08792.5 ABX12105.1 - 0.065 12.7 0.0 0.065 12.7 0.0 3.7 3 1 0 3 3 3 0 A2L zinc ribbon domain zf-B_box PF00643.19 ABX12105.1 - 0.069 13.0 7.9 1.5 8.8 0.3 3.1 3 0 0 3 3 3 0 B-box zinc finger Cript PF10235.4 ABX12105.1 - 0.14 12.5 2.3 1 9.7 0.0 2.9 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT Prim_Zn_Ribbon PF08273.7 ABX12105.1 - 0.44 10.6 10.6 6.7 6.8 0.0 4.0 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-AD PF07776.10 ABX12105.1 - 1 9.3 5.5 1.9 8.5 0.1 2.9 3 1 0 3 3 3 0 Zinc-finger associated domain (zf-AD) NOB1_Zn_bind PF08772.6 ABX12105.1 - 1.1 9.0 9.2 2.3 8.0 2.0 2.6 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like GFA PF04828.9 ABX12105.1 - 1.9 8.4 9.9 19 5.2 1.2 3.5 2 2 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.7 ABX12105.1 - 2.8 7.3 9.2 2.8 7.3 0.1 3.5 2 1 0 2 2 2 0 TFIIB zinc-binding zf-FPG_IleRS PF06827.9 ABX12105.1 - 3.4 7.3 8.0 30 4.3 0.0 3.6 3 1 1 4 4 4 0 Zinc finger found in FPG and IleRS RRN7 PF11781.3 ABX12105.1 - 5.2 6.6 11.9 4.1 7.0 1.6 3.4 3 1 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF1033 PF06279.6 ABX12105.1 - 6 6.7 5.9 3.1 7.6 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1033) Nudix_N_2 PF14803.1 ABX12105.1 - 6.5 6.5 12.2 0.67 9.6 0.2 3.8 4 0 0 4 4 4 0 Nudix N-terminal Prok-RING_1 PF14446.1 ABX12105.1 - 6.7 6.5 7.9 8.4 6.2 0.5 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 GCC2_GCC3 PF07699.8 ABX12105.1 - 9.5 5.8 9.5 2.7 7.6 1.4 3.1 3 0 0 3 3 3 0 GCC2 and GCC3 Thioredoxin PF00085.15 ABX12106.1 - 1.1e-30 105.3 0.1 1.2e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 ABX12106.1 - 9.3e-12 44.9 0.2 1.4e-07 31.5 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 ABX12106.1 - 8.5e-11 42.0 0.0 2.8e-10 40.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ABX12106.1 - 6e-07 29.3 0.1 8.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 ABX12106.1 - 4e-06 26.4 0.0 4.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 ABX12106.1 - 2.2e-05 24.1 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 ABX12106.1 - 6.8e-05 22.5 0.0 8.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ABX12106.1 - 7.8e-05 22.2 0.1 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin HyaE PF07449.6 ABX12106.1 - 0.00074 19.3 0.0 0.00092 19.0 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 ABX12106.1 - 0.0035 17.3 0.1 0.1 12.5 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin TraF PF13728.1 ABX12106.1 - 0.0052 16.2 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF953 PF06110.6 ABX12106.1 - 0.0068 15.8 0.3 0.019 14.4 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) DUF836 PF05768.9 ABX12106.1 - 0.039 14.1 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_6 PF13848.1 ABX12106.1 - 0.039 13.7 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain zinc_ribbon_2 PF13240.1 ABX12107.1 - 2.7e-09 36.2 10.1 1e-07 31.2 2.9 1.6 1 1 1 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.1 ABX12107.1 - 5.9e-09 34.8 3.3 9.5e-09 34.1 2.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 ABX12107.1 - 8.4e-07 28.7 1.1 1.2e-06 28.2 0.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.4 ABX12107.1 - 1.8e-05 24.3 3.0 0.00016 21.2 2.2 2.0 1 1 1 2 2 2 2 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.1 ABX12107.1 - 0.00024 20.7 4.1 0.083 12.5 0.1 2.4 2 0 0 2 2 2 2 Nudix N-terminal GFA PF04828.9 ABX12107.1 - 0.02 14.7 4.3 0.49 10.3 0.1 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 ABX12107.1 - 0.031 13.9 3.7 2.1 8.0 0.4 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-DHHC PF01529.15 ABX12107.1 - 0.032 13.6 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase zf-NADH-PPase PF09297.6 ABX12107.1 - 0.039 13.4 6.0 5.3 6.6 4.2 2.2 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Prok-RING_1 PF14446.1 ABX12107.1 - 0.048 13.3 1.8 0.072 12.8 1.2 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 RRN7 PF11781.3 ABX12107.1 - 0.097 12.1 1.2 10 5.7 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 A2L_zn_ribbon PF08792.5 ABX12107.1 - 0.1 12.0 5.7 2.1 7.9 0.6 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain YhfH PF14149.1 ABX12107.1 - 0.14 11.9 3.9 1.9 8.3 0.1 2.3 1 1 1 2 2 2 0 YhfH-like protein NOB1_Zn_bind PF08772.6 ABX12107.1 - 0.18 11.6 7.7 2 8.3 0.6 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF35_N PF12172.3 ABX12107.1 - 0.26 11.2 1.9 0.62 10.0 1.3 1.6 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) C1_1 PF00130.17 ABX12107.1 - 0.27 10.9 1.7 0.4 10.4 1.1 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Auto_anti-p27 PF06677.7 ABX12107.1 - 0.33 10.7 4.1 16 5.3 2.7 2.3 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.7 ABX12107.1 - 0.4 10.0 2.8 6 6.2 0.3 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-tcix PF14952.1 ABX12107.1 - 0.75 9.1 5.9 3.2 7.1 0.6 2.2 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding RecR PF02132.10 ABX12107.1 - 0.9 9.0 3.0 8.6 5.8 0.1 2.2 1 1 1 2 2 2 0 RecR protein zinc_ribbon_2 PF13240.1 ABX12108.1 - 9.2e-08 31.3 3.6 1.5e-07 30.7 2.5 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 ABX12108.1 - 7.7e-06 24.9 6.2 1.4e-05 24.1 4.3 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 ABX12108.1 - 0.00013 21.7 3.2 0.00019 21.1 2.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon PAH PF02671.16 ABX12108.1 - 0.00084 18.9 0.1 0.002 17.7 0.1 1.6 1 0 0 1 1 1 1 Paired amphipathic helix repeat zf-NADH-PPase PF09297.6 ABX12108.1 - 0.23 10.9 3.1 6.3 6.3 2.2 2.3 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 ABX12108.1 - 4 7.1 6.3 5.6 6.7 0.5 2.2 2 0 0 2 2 2 0 Nudix N-terminal DUF1610 PF07754.6 ABX12108.1 - 5 7.3 6.3 4.7 7.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) DnaJ_CXXCXGXG PF00684.14 ABX12109.1 - 0.081 12.9 10.2 0.29 11.2 7.1 1.9 1 1 0 1 1 1 0 DnaJ central domain Ribosomal_L33 PF00471.15 ABX12109.1 - 0.64 10.3 2.7 1.7 8.9 1.9 1.6 1 0 0 1 1 1 0 Ribosomal protein L33 Antifungal_prot PF11402.3 ABX12109.1 - 1.4 9.1 11.1 10 6.4 7.7 2.1 1 1 0 1 1 1 0 Antifungal protein DZR PF12773.2 ABX12109.1 - 3.4 7.5 12.5 2 8.3 1.1 2.4 2 1 0 2 2 2 0 Double zinc ribbon Amidohydro_4 PF13147.1 ABX12110.1 - 1e-20 74.8 0.0 2.8e-19 70.2 0.0 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 ABX12110.1 - 4.2e-10 39.2 0.9 2.3e-09 36.9 0.7 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 ABX12110.1 - 1.7e-08 34.5 0.1 0.00018 21.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family TatD_DNase PF01026.16 ABX12110.1 - 1.2e-05 24.6 0.1 2.6e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 TatD related DNase Amidohydro_3 PF07969.6 ABX12110.1 - 0.00069 18.9 0.0 0.035 13.3 0.0 2.7 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_2 PF04909.9 ABX12110.1 - 0.051 13.1 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase Memo PF01875.12 ABX12111.1 - 1.6e-82 276.4 0.2 1.9e-82 276.2 0.1 1.0 1 0 0 1 1 1 1 Memo-like protein LigB PF02900.13 ABX12111.1 - 0.006 15.6 0.0 0.019 13.9 0.0 1.7 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase SLEI_Leptospira PF07620.6 ABX12111.1 - 0.025 14.3 0.1 2.1 8.3 0.0 2.9 2 0 0 2 2 2 0 SLEI AMMECR1 PF01871.12 ABX12112.1 - 9.7e-59 197.3 0.0 1.2e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Radical_SAM PF04055.16 ABX12113.1 - 4.9e-14 52.8 1.2 1.2e-13 51.6 0.0 2.2 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.1 ABX12113.1 - 0.003 17.6 0.0 0.003 17.6 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Rib_5-P_isom_A PF06026.9 ABX12114.1 - 5.5e-52 175.5 0.2 6.9e-52 175.2 0.2 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 ABX12114.1 - 0.002 17.8 0.1 0.089 12.4 0.0 2.1 2 0 0 2 2 2 1 DeoR C terminal sensor domain Yqai PF09466.5 ABX12114.1 - 0.064 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Hypothetical protein Yqai Flagellin_C PF00700.16 ABX12115.1 - 0.005 16.9 0.3 0.017 15.2 0.2 2.0 1 0 0 1 1 1 1 Bacterial flagellin C-terminal helical region Ribosomal_L37e PF01907.14 ABX12116.1 - 1.7e-21 75.7 10.4 1.7e-21 75.7 7.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L37e HypA PF01155.14 ABX12116.1 - 0.0039 16.8 1.1 0.0044 16.6 0.8 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 ABX12116.1 - 0.0048 16.6 1.2 0.0053 16.5 0.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 ABX12116.1 - 0.0056 15.8 1.3 0.008 15.3 0.9 1.2 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_6 PF14599.1 ABX12116.1 - 0.0063 16.2 1.1 0.0075 16.0 0.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon Stc1 PF12898.2 ABX12116.1 - 0.025 14.6 1.2 0.028 14.4 0.9 1.1 1 0 0 1 1 1 0 Stc1 domain DNA_RNApol_7kD PF03604.8 ABX12116.1 - 0.029 13.8 8.3 0.055 12.9 2.3 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Baculo_ME53 PF06061.6 ABX12116.1 - 0.045 12.7 1.3 0.045 12.7 0.9 1.0 1 0 0 1 1 1 0 Baculoviridae ME53 Cation_ATPase_N PF00690.21 ABX12116.1 - 0.069 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus OrfB_Zn_ribbon PF07282.6 ABX12116.1 - 0.12 11.9 3.6 0.18 11.5 2.5 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 ABX12116.1 - 0.16 11.9 3.8 1.8 8.5 0.2 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-Mss51 PF13824.1 ABX12116.1 - 0.28 11.0 4.0 2.8 7.8 2.8 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2688 PF10892.3 ABX12116.1 - 0.32 10.6 5.2 0.21 11.2 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) zf-HIT PF04438.11 ABX12116.1 - 0.4 10.3 4.2 2.7 7.7 0.2 2.2 2 0 0 2 2 2 0 HIT zinc finger Ribosomal_S14 PF00253.16 ABX12116.1 - 2.1 7.7 9.0 2.3 7.6 0.4 2.1 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zinc_ribbon_2 PF13240.1 ABX12116.1 - 2.1 7.9 5.6 4.6 6.8 3.9 1.5 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ABX12116.1 - 4.3 7.1 6.5 2.8 7.6 0.8 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 ABX12116.1 - 5.5 6.6 6.6 3.1 7.4 0.8 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.4 ABX12116.1 - 8.8 6.2 7.0 6.1 6.7 0.2 2.1 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain LSM PF01423.17 ABX12117.1 - 2.4e-21 75.0 0.2 2.8e-21 74.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain Creatininase PF02633.9 ABX12118.1 - 6e-57 192.4 0.0 7.1e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase Amidase_3 PF01520.13 ABX12118.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase Formyl_trans_N PF00551.14 ABX12119.1 - 4.9e-42 143.5 0.0 8e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase ACT_6 PF13740.1 ABX12119.1 - 4e-09 36.0 0.1 1.1e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.1 ABX12119.1 - 0.019 15.3 1.4 0.065 13.5 0.0 2.5 2 1 0 2 2 2 0 ACT domain DUF4411 PF14367.1 ABX12119.1 - 0.022 14.4 1.0 0.057 13.1 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) PGM_PMM_I PF02878.11 ABX12120.1 - 2.9e-38 130.4 0.0 5.1e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 ABX12120.1 - 1.2e-23 83.3 0.0 3.2e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 ABX12120.1 - 3e-20 72.3 0.0 5.1e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 ABX12120.1 - 4.2e-11 42.6 0.0 1.1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ribosomal_L7Ae PF01248.21 ABX12121.1 - 8.3e-25 86.1 0.1 9.9e-25 85.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.1 ABX12121.1 - 0.024 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF3055 PF11256.3 ABX12121.1 - 0.025 14.6 0.0 0.04 14.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3055) Ribosomal_S28e PF01200.13 ABX12122.1 - 5.9e-29 99.6 5.0 6.3e-29 99.5 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_L24e PF01246.15 ABX12123.1 - 1e-17 63.7 1.0 1e-17 63.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L24e DUF2256 PF10013.4 ABX12123.1 - 0.0062 16.2 7.5 4.1 7.2 0.1 3.1 3 0 0 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2256) DUF581 PF04570.9 ABX12123.1 - 0.02 14.1 0.2 0.033 13.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF581) zf-MYND PF01753.13 ABX12123.1 - 0.067 13.0 0.1 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 MYND finger zf-FCS PF06467.9 ABX12123.1 - 0.24 11.0 4.2 0.079 12.6 1.0 1.6 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF329 PF03884.9 ABX12123.1 - 0.67 9.5 2.9 2.7 7.6 2.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF329) NDK PF00334.14 ABX12124.1 - 6.6e-51 171.6 0.1 7.3e-51 171.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase GTP_EFTU PF00009.22 ABX12125.1 - 5.6e-33 113.9 0.0 1.9e-32 112.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 ABX12125.1 - 6.2e-23 80.7 1.1 1.7e-22 79.3 0.8 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.1 ABX12125.1 - 4.7e-10 38.9 0.3 1.9e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 ABX12125.1 - 1.5e-07 31.3 0.0 5.8e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ABX12125.1 - 3.9e-07 30.5 0.1 1.8e-05 25.2 0.0 3.0 3 0 0 3 3 3 1 Miro-like protein ATP_bind_1 PF03029.12 ABX12125.1 - 1.6e-05 24.6 0.0 7.9e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU_D2 PF03144.20 ABX12125.1 - 3.5e-05 23.8 0.1 0.00015 21.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Dynamin_N PF00350.18 ABX12125.1 - 0.00014 21.7 0.2 0.05 13.4 0.0 2.9 1 1 1 2 2 2 1 Dynamin family Ras PF00071.17 ABX12125.1 - 0.0043 16.4 0.0 0.025 13.9 0.0 2.3 1 1 0 1 1 1 1 Ras family cobW PF02492.14 ABX12125.1 - 0.027 13.9 0.1 2.2 7.6 0.1 2.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Thioredoxin PF00085.15 ABX12126.1 - 4.8e-31 106.5 0.1 7e-31 105.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 ABX12126.1 - 8.2e-10 38.6 0.9 6.9e-08 32.5 0.1 2.4 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 ABX12126.1 - 1.8e-09 37.8 1.0 6.8e-09 35.9 0.2 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.5 ABX12126.1 - 7.2e-08 32.0 0.1 8.7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 ABX12126.1 - 1.8e-06 27.5 0.3 2.5e-06 27.0 0.2 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 ABX12126.1 - 5.4e-05 23.1 0.1 9.5e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.11 ABX12126.1 - 0.00017 20.4 0.0 0.0002 20.1 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin_3 PF13192.1 ABX12126.1 - 0.00081 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 ABX12126.1 - 0.0014 18.2 0.1 0.0027 17.3 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.1 ABX12126.1 - 0.012 15.1 0.1 0.02 14.3 0.1 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein DUF836 PF05768.9 ABX12126.1 - 0.03 14.5 0.0 0.073 13.3 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) HyaE PF07449.6 ABX12126.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE UAA PF08449.6 ABX12126.1 - 0.072 12.0 0.1 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 UAA transporter family Glutaredoxin PF00462.19 ABX12126.1 - 0.13 12.2 0.1 0.87 9.6 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_4 PF13462.1 ABX12126.1 - 0.3 11.0 1.6 7.8 6.4 0.2 2.4 1 1 2 3 3 3 0 Thioredoxin He_PIG PF05345.7 ABX12127.1 - 1.5e-05 24.8 0.8 1.5e-05 24.8 0.6 3.0 3 0 0 3 3 3 1 Putative Ig domain Methyltransf_33 PF10017.4 ABX12127.1 - 0.36 10.7 1.9 21 4.9 0.1 2.4 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent Occludin_ELL PF07303.8 ABX12127.1 - 1.4 9.6 9.5 5.9 7.6 0.2 2.9 3 0 0 3 3 3 0 Occludin homology domain Archease PF01951.11 ABX12128.1 - 5.9e-35 120.2 0.5 6.4e-35 120.0 0.3 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) RdgC PF04381.7 ABX12128.1 - 0.0011 18.0 0.1 0.0013 17.7 0.1 1.1 1 0 0 1 1 1 1 Putative exonuclease, RdgC Glyoxalase_2 PF12681.2 ABX12129.1 - 9.8e-09 35.7 0.0 1.3e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 ABX12129.1 - 0.037 14.0 0.0 0.091 12.7 0.0 1.5 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SNARE_assoc PF09335.6 ABX12130.1 - 5.7e-22 78.2 4.0 9e-22 77.5 2.7 1.3 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF1059 PF06348.6 ABX12131.1 - 8.6e-21 73.5 0.6 9.3e-21 73.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) tRNA-synt_His PF13393.1 ABX12132.1 - 6.3e-48 163.4 0.0 8.4e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 ABX12132.1 - 2e-17 63.2 0.1 3.7e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ABX12132.1 - 8.5e-11 41.6 0.1 2.5e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.15 ABX12132.1 - 3.9e-05 22.9 0.0 9.3e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) RPT PF13446.1 ABX12132.1 - 0.08 12.3 0.3 0.21 11.0 0.2 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein Trypan_glycop PF00913.14 ABX12132.1 - 0.19 10.6 0.4 0.31 9.8 0.3 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) eIF-6 PF01912.13 ABX12133.1 - 8.2e-69 230.6 2.0 1e-68 230.3 1.4 1.1 1 0 0 1 1 1 1 eIF-6 family Fer4 PF00037.22 ABX12134.1 - 6e-10 38.2 11.9 4.7e-06 25.9 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 ABX12134.1 - 1.1e-09 38.5 4.2 0.00021 21.5 1.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 ABX12134.1 - 9.1e-09 35.2 0.7 0.0019 18.2 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 ABX12134.1 - 2.1e-08 33.8 17.4 2e-06 27.4 5.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 ABX12134.1 - 1.3e-07 31.7 7.1 6.6e-07 29.4 4.9 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 ABX12134.1 - 2.1e-07 30.6 2.8 0.00082 19.1 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 ABX12134.1 - 4e-07 29.6 12.5 0.00063 19.5 2.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 ABX12134.1 - 3.2e-06 26.7 11.7 0.0055 16.5 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 ABX12134.1 - 4.9e-06 27.0 7.1 0.0031 18.0 0.6 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_16 PF13484.1 ABX12134.1 - 5.3e-06 27.0 6.9 0.0014 19.3 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.2 ABX12134.1 - 3.7e-05 23.7 6.8 0.035 14.4 1.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 ABX12134.1 - 6.6e-05 23.2 9.2 0.00054 20.3 4.8 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 ABX12134.1 - 0.00015 22.0 5.4 0.0032 17.7 4.8 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_11 PF13247.1 ABX12134.1 - 0.0025 17.6 1.4 1.6 8.6 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 ABX12134.1 - 0.0029 17.9 12.3 0.18 12.2 2.1 2.8 3 1 0 3 3 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 ABX12134.1 - 0.044 14.3 16.2 0.18 12.4 1.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.2 ABX12135.1 - 8.1e-11 42.1 2.2 3.4e-05 24.1 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.22 ABX12135.1 - 1.2e-10 40.5 6.9 4.9e-06 25.9 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 ABX12135.1 - 2.6e-10 40.1 14.2 2e-08 34.1 5.6 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 ABX12135.1 - 6.9e-09 35.8 6.4 1.7e-08 34.5 4.4 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 ABX12135.1 - 2e-08 33.9 20.8 5.9e-06 25.9 7.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 ABX12135.1 - 4.7e-08 32.7 3.2 0.002 17.9 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 ABX12135.1 - 6e-08 33.3 2.2 0.00013 22.6 0.7 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.1 ABX12135.1 - 1.6e-07 31.5 4.1 3.4e-07 30.5 2.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 ABX12135.1 - 1.5e-06 27.7 10.4 0.00047 19.9 2.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 ABX12135.1 - 2.7e-06 26.9 10.3 0.0024 17.6 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 ABX12135.1 - 0.00013 22.3 10.6 0.00085 19.7 5.8 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 ABX12135.1 - 0.00019 21.9 4.7 0.086 13.4 0.1 2.7 3 0 0 3 3 2 2 4Fe-4S single cluster domain Fer4_4 PF12800.2 ABX12135.1 - 0.00029 20.9 10.7 0.0047 17.1 1.0 2.4 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 ABX12135.1 - 0.00063 20.0 7.4 0.062 13.6 0.9 2.7 3 0 0 3 3 3 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 ABX12135.1 - 0.0019 18.5 16.0 0.032 14.7 4.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_11 PF13247.1 ABX12135.1 - 0.011 15.5 1.8 2.2 8.2 0.2 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_20 PF14691.1 ABX12135.1 - 0.03 13.9 1.9 0.3 10.7 0.4 2.1 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DNA_pol3_delta2 PF13177.1 ABX12136.1 - 5.3e-16 58.7 0.6 7.9e-12 45.1 0.2 2.6 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 ABX12136.1 - 3.1e-13 49.5 2.0 1.4e-12 47.4 0.2 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 ABX12136.1 - 2.9e-12 46.9 0.5 8.3e-12 45.4 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 ABX12136.1 - 8.1e-08 31.3 0.5 0.0036 16.0 0.4 2.5 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 ABX12136.1 - 1.1e-05 25.5 1.4 0.012 15.7 0.0 2.7 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 ABX12136.1 - 3.7e-05 22.8 0.0 0.00028 19.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 ABX12136.1 - 4e-05 23.1 0.4 0.0001 21.8 0.1 1.7 2 0 0 2 2 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 ABX12136.1 - 0.00022 21.2 0.2 0.016 15.1 0.0 2.5 2 1 0 3 3 3 1 AAA ATPase domain AAA_3 PF07726.6 ABX12136.1 - 0.00034 20.2 0.0 0.00062 19.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 ABX12136.1 - 0.0034 16.5 0.0 0.37 9.9 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DEAD PF00270.24 ABX12136.1 - 0.0035 16.8 0.9 0.058 12.8 0.1 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_10 PF12846.2 ABX12136.1 - 0.0038 16.7 1.1 2.6 7.3 0.2 2.6 2 1 1 3 3 3 2 AAA-like domain TIP49 PF06068.8 ABX12136.1 - 0.0087 14.8 1.9 1.5 7.4 0.0 2.9 1 1 1 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 ABX12136.1 - 0.014 15.6 1.9 0.041 14.1 0.3 2.4 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 ABX12136.1 - 0.015 15.0 0.1 0.17 11.7 0.1 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.9 ABX12136.1 - 0.03 14.0 0.3 0.25 11.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 ABX12136.1 - 0.045 12.6 0.0 0.18 10.6 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 ABX12136.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PTPlike_phytase PF14566.1 ABX12136.1 - 0.099 12.6 0.1 0.38 10.7 0.0 2.0 2 1 0 2 2 2 0 Inositol hexakisphosphate RHH_1 PF01402.16 ABX12136.1 - 0.2 11.6 2.8 20 5.2 0.0 2.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Sld5 PF05916.6 ABX12137.1 - 1.8e-07 31.4 0.2 2.5e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein DUF620 PF04788.7 ABX12137.1 - 0.095 11.8 0.1 0.18 10.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF620) MCM PF00493.18 ABX12138.1 - 2.3e-124 414.5 0.1 3.2e-124 414.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 ABX12138.1 - 4.2e-18 65.9 0.7 1.3e-17 64.3 0.2 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 ABX12138.1 - 3.2e-06 26.4 0.0 0.00025 20.2 0.0 2.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 ABX12138.1 - 7.1e-06 25.7 0.0 0.00028 20.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 ABX12138.1 - 0.0027 17.2 0.0 0.0087 15.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 ABX12139.1 - 1.4e-28 99.5 0.0 3.3e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ABX12139.1 - 1.9e-10 40.4 0.0 4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 ABX12139.1 - 9.7e-10 38.4 0.9 3.1e-09 36.8 0.6 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain ResIII PF04851.10 ABX12139.1 - 3e-08 33.7 0.2 1e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_2 PF12826.2 ABX12139.1 - 5.6e-07 29.3 0.5 2.5e-05 24.0 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif Sec63 PF02889.11 ABX12139.1 - 6.1e-06 25.6 2.0 6.4e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Sec63 Brl domain DNA_pol_lambd_f PF10391.4 ABX12139.1 - 0.00084 18.8 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DUF4332 PF14229.1 ABX12139.1 - 0.0073 16.2 0.1 0.036 14.0 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4332) T2SE PF00437.15 ABX12139.1 - 0.044 12.6 0.0 0.087 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 ABX12139.1 - 0.048 13.0 0.0 0.27 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain Cactin_mid PF10312.4 ABX12139.1 - 0.11 11.8 1.0 0.89 8.7 0.4 2.1 2 0 0 2 2 2 0 Conserved mid region of cactin Glycos_transf_4 PF00953.16 ABX12140.1 - 1.9e-26 92.7 15.5 1.9e-26 92.7 10.7 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 4 Big_3_3 PF13750.1 ABX12140.1 - 0.024 14.0 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Hexapep PF00132.19 ABX12141.1 - 1e-26 91.2 13.6 2.4e-10 39.4 0.4 3.6 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ABX12141.1 - 3.1e-19 68.2 9.2 8.3e-10 38.0 1.5 4.3 3 1 1 4 4 4 4 Hexapeptide repeat of succinyl-transferase Trm112p PF03966.11 ABX12142.1 - 5.3e-08 33.1 0.4 1.7e-07 31.4 0.3 1.9 1 1 0 1 1 1 1 Trm112p-like protein DUF2719 PF10891.3 ABX12142.1 - 0.11 12.1 0.1 0.34 10.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2719) GFO_IDH_MocA PF01408.17 ABX12143.1 - 6.4e-27 94.4 0.0 1.5e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ABX12143.1 - 2.2e-09 37.0 0.0 4.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 ABX12143.1 - 0.011 16.0 0.1 0.029 14.6 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CAP_assoc_N PF14504.1 ABX12143.1 - 0.015 14.9 0.5 0.028 14.1 0.3 1.4 1 0 0 1 1 1 0 CAP-associated N-terminal Peptidase_M73 PF12389.3 ABX12143.1 - 0.017 14.6 0.1 0.036 13.5 0.1 1.4 1 1 0 1 1 1 0 Camelysin metallo-endopeptidase ATP-synt_F PF01990.12 ABX12143.1 - 0.031 14.6 0.5 0.1 12.9 0.4 1.9 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit IlvN PF07991.7 ABX12143.1 - 0.041 13.2 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Aminotran_4 PF01063.14 ABX12144.1 - 2e-42 145.2 0.0 2.3e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV HATPase_c PF02518.21 ABX12145.1 - 1.3e-21 76.4 1.4 1.8e-21 75.9 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ABX12145.1 - 1.2e-12 47.6 0.0 5.4e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 ABX12145.1 - 8e-08 32.3 0.0 2.5e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.1 ABX12145.1 - 2.5e-06 27.1 0.1 2.5e-06 27.1 0.1 2.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cytochrom_B562 PF07361.6 ABX12145.1 - 0.0019 18.5 1.1 0.0053 17.1 0.2 2.1 1 1 1 2 2 2 1 Cytochrome b562 IncA PF04156.9 ABX12145.1 - 0.013 15.1 0.3 0.034 13.7 0.2 1.8 1 1 0 1 1 1 0 IncA protein Phosphonate-bd PF12974.2 ABX12146.1 - 1.1e-45 155.9 0.0 1.4e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Response_reg PF00072.19 ABX12147.1 - 2.4e-20 72.6 0.5 2.7e-20 72.4 0.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.14 ABX12147.1 - 0.0026 17.6 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 B12 binding domain Saccharop_dh_N PF04455.7 ABX12147.1 - 0.099 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region Tbf5 PF06331.7 ABX12147.1 - 0.11 12.3 0.4 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 CTP_transf_2 PF01467.21 ABX12148.1 - 0.01 15.9 0.0 0.018 15.0 0.0 1.5 1 1 0 1 1 1 0 Cytidylyltransferase NAD_binding_1 PF00175.16 ABX12149.1 - 4.2e-14 53.0 0.0 9.7e-14 51.8 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ABX12149.1 - 6e-11 42.3 0.0 8.6e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 ABX12149.1 - 0.14 12.0 0.2 0.47 10.3 0.1 1.9 1 1 1 2 2 2 0 Ferric reductase NAD binding domain HEAT_2 PF13646.1 ABX12150.1 - 2.3e-17 63.0 0.6 3.7e-10 39.9 0.1 2.7 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.17 ABX12150.1 - 9.9e-12 43.8 0.1 0.13 12.4 0.0 4.5 4 0 0 4 4 4 4 HEAT repeat HEAT_EZ PF13513.1 ABX12150.1 - 6.8e-10 39.1 0.2 0.072 13.6 0.0 4.2 3 1 1 4 4 4 3 HEAT-like repeat Cnd1 PF12717.2 ABX12150.1 - 0.0025 17.6 1.2 0.11 12.2 0.2 2.9 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ABX12150.1 - 0.0066 16.8 0.3 3.1 8.2 0.0 2.9 1 1 2 3 3 3 1 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 ABX12150.1 - 0.025 14.5 1.3 11 6.0 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Sigma70_r1_1 PF03979.9 ABX12150.1 - 0.027 14.4 0.7 0.12 12.3 0.2 2.3 1 1 1 2 2 2 0 Sigma-70 factor, region 1.1 DUF2435 PF10363.4 ABX12150.1 - 0.065 13.1 0.4 0.8 9.6 0.0 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF2435) DUF3674 PF12426.3 ABX12150.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA dependent RNA polymerase MgtE_N PF03448.12 ABX12150.1 - 0.15 12.3 2.6 0.67 10.2 0.1 2.9 2 1 1 3 3 3 0 MgtE intracellular N domain Alba PF01918.16 ABX12151.1 - 8.2e-10 38.1 0.1 1.1e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 ABX12151.1 - 0.053 13.1 0.6 2.7 7.6 0.0 2.1 1 1 1 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P PEP_mutase PF13714.1 ABX12152.1 - 3.5e-55 186.8 0.1 4e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 ABX12152.1 - 9.7e-18 63.6 0.2 3.6e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 Isocitrate lyase family Pantoate_transf PF02548.10 ABX12152.1 - 0.0076 15.4 0.1 0.57 9.2 0.0 2.8 2 1 1 3 3 3 1 Ketopantoate hydroxymethyltransferase HisG_C PF08029.6 ABX12152.1 - 0.07 13.0 0.0 0.41 10.6 0.0 2.3 2 0 0 2 2 2 0 HisG, C-terminal domain PadR PF03551.9 ABX12153.1 - 3.4e-11 42.7 0.3 7.1e-11 41.7 0.2 1.6 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.1 ABX12153.1 - 4.2e-07 29.6 2.0 1.2e-05 25.0 0.0 2.5 3 0 0 3 3 3 1 Winged helix-turn-helix Mrr_N PF14338.1 ABX12153.1 - 0.0053 16.8 0.6 0.036 14.1 0.0 2.4 3 0 0 3 3 3 1 Mrr N-terminal domain DisA-linker PF10635.4 ABX12153.1 - 0.0087 15.5 2.8 0.011 15.2 0.7 1.9 2 1 0 2 2 2 1 DisA bacterial checkpoint controller linker region Pox_E6 PF04656.7 ABX12153.1 - 0.01 14.1 0.0 0.013 13.7 0.0 1.1 1 0 0 1 1 1 1 Pox virus E6 protein Stork_head PF10264.4 ABX12153.1 - 0.031 14.4 0.1 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain AphA_like PF14557.1 ABX12153.1 - 0.091 12.3 0.0 0.12 11.9 0.0 1.3 1 1 0 1 1 1 0 Putative AphA-like transcriptional regulator HTH_27 PF13463.1 ABX12153.1 - 0.091 13.0 0.0 0.48 10.7 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain FAD_binding_2 PF00890.19 ABX12154.1 - 9.2e-99 331.0 0.4 1.3e-98 330.6 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 ABX12154.1 - 9.4e-38 128.9 0.7 1.5e-37 128.2 0.5 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 ABX12154.1 - 2e-06 27.8 1.1 0.004 17.0 0.6 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ABX12154.1 - 0.00047 19.3 1.2 0.0026 16.8 0.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 ABX12154.1 - 0.0036 16.4 0.5 0.013 14.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 ABX12154.1 - 0.0084 15.0 1.6 0.047 12.5 1.1 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 ABX12154.1 - 0.03 13.2 0.2 0.13 11.1 0.1 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ABX12154.1 - 0.04 12.8 0.2 0.077 11.9 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Sdh_cyt PF01127.17 ABX12155.1 - 3e-08 33.5 4.1 4.7e-08 32.9 2.4 1.6 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DDE_Tnp_1_2 PF13586.1 ABX12155.1 - 0.072 13.2 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Sdh_cyt PF01127.17 ABX12156.1 - 9.6e-09 35.1 4.2 1.3e-08 34.7 2.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ferric_reduct PF01794.14 ABX12156.1 - 0.29 11.2 5.6 0.42 10.7 3.9 1.4 1 1 0 1 1 1 0 Ferric reductase like transmembrane component DUF4405 PF14358.1 ABX12156.1 - 0.3 11.2 4.6 0.28 11.3 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Fer2_3 PF13085.1 ABX12157.1 - 1.6e-30 105.1 0.0 3.2e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.1 ABX12157.1 - 3.6e-12 46.1 4.8 8e-12 45.0 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 ABX12157.1 - 9.8e-10 38.7 7.1 9.7e-09 35.5 0.3 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 ABX12157.1 - 9.1e-09 35.5 1.4 9.1e-09 35.5 1.0 2.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 ABX12157.1 - 1.1e-08 35.1 2.4 1.1e-08 35.1 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 ABX12157.1 - 2.1e-08 33.8 2.5 2.1e-08 33.8 1.8 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 ABX12157.1 - 3.2e-08 33.8 14.0 6.9e-07 29.5 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 ABX12157.1 - 6.2e-05 22.6 0.9 0.00014 21.5 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_2 PF12797.2 ABX12157.1 - 9.5e-05 22.1 12.9 0.00017 21.2 1.2 3.4 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4 PF00037.22 ABX12157.1 - 0.00013 21.3 1.6 0.00013 21.3 1.1 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.1 ABX12157.1 - 0.00078 20.1 7.0 0.00082 20.0 3.0 2.3 2 1 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_6 PF12837.2 ABX12157.1 - 0.0058 16.4 2.1 0.0058 16.4 1.4 2.9 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_4 PF12800.2 ABX12157.1 - 0.074 13.4 1.9 0.074 13.4 1.3 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain FpoO PF10621.4 ABX12157.1 - 0.091 12.8 1.1 0.42 10.6 0.0 2.3 3 0 0 3 3 3 0 F420H2 dehydrogenase subunit FpoO Fer4_21 PF14697.1 ABX12157.1 - 0.096 12.5 11.9 0.18 11.6 5.4 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.2 ABX12157.1 - 0.15 12.7 0.9 0.15 12.7 0.6 3.1 3 0 0 3 3 2 0 4Fe-4S binding domain DUF59 PF01883.14 ABX12158.1 - 1e-13 51.0 0.1 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF59 Lyase_1 PF00206.15 ABX12159.1 - 4.1e-51 174.0 0.0 6.4e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 ABX12159.1 - 1.2e-13 50.8 0.1 1.6e-12 47.3 0.0 2.7 3 0 0 3 3 3 1 Argininosuccinate lyase C-terminal DUF390 PF04094.9 ABX12160.1 - 0.5 8.3 21.9 0.59 8.1 15.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Borrelia_P83 PF05262.6 ABX12160.1 - 3.4 5.8 20.1 3.5 5.7 13.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Med8 PF10232.4 ABX12160.1 - 8 5.9 8.7 13 5.1 6.0 1.4 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 GlutR_N PF05201.10 ABX12161.1 - 8.3e-30 103.3 0.0 1.3e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.15 ABX12161.1 - 1.4e-15 57.5 0.1 3.7e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 ABX12161.1 - 0.13 11.2 0.0 0.4 9.5 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1059 PF06348.6 ABX12162.1 - 3e-07 30.1 0.1 3.4e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) NAD_binding_1 PF00175.16 ABX12163.1 - 6.8e-13 49.1 0.0 1.5e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ABX12163.1 - 4.8e-10 39.4 0.0 8.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 ABX12163.1 - 0.089 12.6 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DUF3115 PF11312.3 ABX12163.1 - 0.17 10.7 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Inositol_P PF00459.20 ABX12164.1 - 8.9e-31 107.1 0.0 9.6e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 ABX12164.1 - 4.5e-06 25.7 0.0 9.8e-06 24.6 0.0 1.5 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase AAA PF00004.24 ABX12166.1 - 5.4e-13 49.2 0.0 1.2e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 ABX12166.1 - 1.7e-09 36.9 0.2 0.00013 20.8 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 ABX12166.1 - 8.2e-08 31.5 0.0 1.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 ABX12166.1 - 4.3e-05 22.4 0.0 8.4e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 ABX12166.1 - 6e-05 23.8 0.1 0.00023 21.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ABX12166.1 - 0.00033 20.5 0.0 0.00068 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 ABX12166.1 - 0.004 17.0 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.10 ABX12166.1 - 0.0045 16.7 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 1 1 NTPase AAA_18 PF13238.1 ABX12166.1 - 0.0072 16.6 0.0 0.03 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ABX12166.1 - 0.008 16.3 0.0 0.36 10.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 ABX12166.1 - 0.021 13.9 0.1 0.06 12.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 ABX12166.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 ABX12166.1 - 0.048 13.3 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.10 ABX12166.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 ABX12166.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 ABX12166.1 - 0.08 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 ABX12166.1 - 0.082 12.4 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ABX12166.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ABX12166.1 - 0.096 12.8 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 ABX12166.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ABX12166.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Myticin-prepro PF10690.4 ABX12167.1 - 0.068 13.1 5.8 0.098 12.6 4.0 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel DUF2197 PF09963.4 ABX12167.1 - 2.9 7.9 0.0 2.9 7.9 0.0 3.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Carboxyl_trans PF01039.17 ABX12168.1 - 2.7e-187 623.0 0.1 3e-187 622.8 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 ABX12168.1 - 4.9e-06 25.9 0.1 1.4e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) FTCD_C PF04961.7 ABX12168.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase CPSase_L_D2 PF02786.12 ABX12169.1 - 4.2e-70 235.3 0.2 6.3e-70 234.7 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 ABX12169.1 - 1.2e-43 147.6 0.0 2.5e-43 146.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 ABX12169.1 - 6.9e-33 112.8 0.0 1.3e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 ABX12169.1 - 1e-19 71.0 0.1 1.9e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ABX12169.1 - 7.6e-16 57.7 0.0 4.8e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.6 ABX12169.1 - 4.8e-11 42.4 0.0 3.8e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 ABX12169.1 - 6.1e-10 38.7 0.3 1.3e-09 37.6 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ABX12169.1 - 1.6e-08 34.1 0.4 4.7e-08 32.6 0.2 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 ABX12169.1 - 4.5e-08 33.1 0.1 8.1e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 ABX12169.1 - 0.024 13.8 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.1 ABX12169.1 - 0.036 13.1 0.0 0.39 9.7 0.0 2.2 1 1 0 2 2 2 0 Sugar-transfer associated ATP-grasp Biotin_lipoyl PF00364.17 ABX12170.1 - 5.1e-18 64.4 4.9 5.1e-18 64.4 3.4 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 ABX12170.1 - 3.8e-15 55.2 2.2 7.2e-09 35.1 0.2 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_2 PF12700.2 ABX12170.1 - 3.1e-07 29.8 7.0 0.0011 18.2 0.1 2.9 1 1 1 3 3 3 2 HlyD family secretion protein HlyD_3 PF13437.1 ABX12170.1 - 9.2e-07 29.1 0.3 0.017 15.4 0.0 2.8 3 0 0 3 3 3 2 HlyD family secretion protein HlyD PF00529.15 ABX12170.1 - 3.2e-06 26.6 1.7 0.00018 20.9 0.1 2.2 1 1 1 2 2 2 2 HlyD family secretion protein QRPTase_N PF02749.11 ABX12170.1 - 0.00026 20.7 0.4 0.081 12.7 0.0 2.3 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, N-terminal domain Peptidase_M23 PF01551.17 ABX12170.1 - 0.0023 17.9 1.5 1.4 8.9 0.0 2.7 2 1 1 3 3 3 2 Peptidase family M23 GCV_H PF01597.14 ABX12170.1 - 0.0034 17.0 1.7 0.0034 17.0 1.2 2.0 2 1 0 2 2 2 1 Glycine cleavage H-protein RnfC_N PF13375.1 ABX12170.1 - 0.014 15.1 3.1 0.077 12.7 2.1 2.1 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 ABX12170.1 - 0.03 14.0 3.6 0.054 13.1 0.3 2.7 2 2 2 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2118) PYNP_C PF07831.8 ABX12170.1 - 0.033 13.6 1.4 2.5 7.6 0.0 2.9 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain PTS_EIIA_1 PF00358.15 ABX12170.1 - 0.045 13.3 0.4 2 7.9 0.0 2.4 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Staphostatin_B PF09023.5 ABX12170.1 - 0.09 12.6 0.4 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 Staphostatin B PASTA PF03793.14 ABX12170.1 - 0.12 12.0 1.0 3.3 7.4 0.2 2.6 2 0 0 2 2 2 0 PASTA domain AhpC-TSA PF00578.16 ABX12171.1 - 1.1e-32 112.3 0.0 1.3e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ABX12171.1 - 2.5e-23 82.2 0.0 2.9e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 ABX12171.1 - 0.022 14.4 0.1 0.031 13.9 0.0 1.4 1 1 0 1 1 1 0 SCO1/SenC DUF3823 PF12866.2 ABX12171.1 - 0.039 13.4 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) AhpC-TSA_2 PF13911.1 ABX12171.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme M60-like PF13402.1 ABX12171.1 - 0.13 11.1 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase M60-like family Oxidored_q4 PF00507.14 ABX12172.1 - 1.4e-15 56.8 0.4 1.8e-15 56.5 0.3 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Oxidored_q6 PF01058.17 ABX12173.1 - 6.4e-25 87.2 0.1 8.9e-25 86.8 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_30kDa PF00329.14 ABX12174.1 - 2e-26 92.1 0.1 8.2e-26 90.2 0.1 1.8 1 1 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Complex1_49kDa PF00346.14 ABX12175.1 - 5.5e-57 192.8 0.0 1.7e-45 155.1 0.0 2.1 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF3195 PF11424.3 ABX12175.1 - 0.088 12.9 1.0 1 9.6 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3195) NADHdh PF00146.16 ABX12176.1 - 2.3e-79 266.6 14.4 3.4e-79 266.1 10.0 1.2 1 0 0 1 1 1 1 NADH dehydrogenase Fer4 PF00037.22 ABX12177.1 - 6.3e-12 44.5 10.8 2.6e-09 36.2 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 ABX12177.1 - 5.3e-10 38.9 18.1 3.2e-07 30.0 6.9 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 ABX12177.1 - 1.2e-09 38.4 9.5 1.9e-09 37.7 6.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 ABX12177.1 - 1.1e-08 34.8 20.2 3.5e-06 26.7 7.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 ABX12177.1 - 2.5e-08 33.3 10.5 6.8e-05 22.5 1.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 ABX12177.1 - 5e-07 29.8 8.9 8.5e-07 29.1 6.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 ABX12177.1 - 1.7e-06 28.2 6.4 0.0022 18.3 0.1 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 ABX12177.1 - 5.1e-06 26.1 1.8 5.1e-06 26.1 1.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_8 PF13183.1 ABX12177.1 - 8e-06 25.7 19.0 0.00018 21.4 7.3 1.8 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.1 ABX12177.1 - 1.1e-05 26.0 17.4 0.0005 20.7 6.7 1.8 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.2 ABX12177.1 - 1.6e-05 24.8 8.3 0.0024 18.0 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 ABX12177.1 - 0.00031 21.2 4.3 0.086 13.4 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 ABX12177.1 - 0.0018 18.6 4.7 0.17 12.3 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 ABX12177.1 - 0.0031 17.9 17.3 0.0057 17.1 2.8 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_18 PF13746.1 ABX12177.1 - 0.0041 17.5 11.9 0.0058 17.0 0.8 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain DUF2607 PF10795.4 ABX12177.1 - 0.042 13.6 0.2 0.072 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) Oxidored_q3 PF00499.15 ABX12178.1 - 5.8e-21 74.7 5.6 7.7e-21 74.3 3.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4040 PF13244.1 ABX12178.1 - 0.0064 16.4 10.8 0.0064 16.4 7.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4040) MIG-14_Wnt-bd PF06664.7 ABX12178.1 - 0.017 13.9 1.0 0.025 13.3 0.7 1.3 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF4389 PF14333.1 ABX12178.1 - 1.1 8.9 6.6 17 5.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) NfeD PF01957.13 ABX12178.1 - 2.4 8.2 15.5 0.21 11.7 6.3 2.2 1 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding UPF0104 PF03706.8 ABX12178.1 - 3.1 6.9 17.2 0.14 11.3 5.6 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) Oxidored_q2 PF00420.19 ABX12179.1 - 7.2e-22 76.7 4.3 8.7e-22 76.5 3.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Gram_pos_anchor PF00746.16 ABX12179.1 - 5.1 7.0 8.9 2.6 7.9 0.1 2.7 3 1 0 3 3 3 0 Gram positive anchor Oxidored_q1 PF00361.15 ABX12180.1 - 2.5e-64 217.1 24.0 2.5e-64 217.1 16.6 2.3 3 0 0 3 3 3 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 ABX12180.1 - 0.0027 17.2 0.1 0.015 14.8 0.0 2.3 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q1 PF00361.15 ABX12181.1 - 1.4e-56 191.7 31.0 4.6e-52 176.9 13.2 3.7 3 1 1 4 4 4 2 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 ABX12181.1 - 1.7e-11 43.4 2.1 6.8e-11 41.5 1.5 2.1 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q1_C PF01010.14 ABX12181.1 - 0.0023 17.4 0.4 0.022 14.2 0.2 2.2 1 1 1 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus Oxidored_q2 PF00420.19 ABX12181.1 - 0.0095 15.5 2.0 0.0095 15.5 1.4 4.8 4 1 0 4 4 4 2 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Oxidored_q1 PF00361.15 ABX12182.1 - 9.9e-60 202.0 22.1 9.9e-60 202.0 15.3 2.8 4 0 0 4 4 4 2 NADH-Ubiquinone/plastoquinone (complex I), various chains polyprenyl_synt PF00348.12 ABX12183.1 - 6.9e-42 143.0 0.1 9.2e-42 142.6 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase TENA_THI-4 PF03070.11 ABX12184.1 - 1.4e-17 64.1 0.4 1.8e-17 63.8 0.3 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.1 ABX12184.1 - 2.2e-07 31.0 0.0 2.5e-06 27.6 0.0 2.2 1 1 1 2 2 2 1 Iron-containing redox enzyme SCP-1 PF05483.7 ABX12184.1 - 0.061 11.1 0.1 0.065 11.0 0.1 1.2 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Pribosyltran PF00156.22 ABX12185.1 - 1.6e-15 56.9 0.3 3.4e-15 55.8 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 ABX12185.1 - 0.0002 20.7 0.9 0.00062 19.1 0.2 2.0 2 1 0 2 2 2 1 Phosphoribosyl transferase UPRTase PF14681.1 ABX12185.1 - 0.00027 20.1 0.3 0.00036 19.7 0.2 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase NPV_P10 PF05531.7 ABX12185.1 - 0.046 13.9 1.8 0.089 13.0 1.2 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SmpB PF01668.13 ABX12185.1 - 0.086 12.6 0.1 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 SmpB protein Peptidase_M50 PF02163.17 ABX12187.1 - 2.3e-17 62.5 6.8 2.4e-16 59.2 3.3 2.7 2 1 0 2 2 2 1 Peptidase family M50 Acetyltransf_1 PF00583.19 ABX12188.1 - 2.5e-17 62.6 0.2 3.7e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ABX12188.1 - 5.8e-09 36.1 0.0 8.6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ABX12188.1 - 1.1e-08 35.0 0.3 1.7e-08 34.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ABX12188.1 - 2e-08 33.8 0.1 7.9e-08 31.9 0.0 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 ABX12188.1 - 1.2e-06 28.4 0.1 2.2e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ABX12188.1 - 0.00034 20.5 0.0 0.00046 20.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ABX12188.1 - 0.0014 18.7 0.0 0.0019 18.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ABX12188.1 - 0.0026 17.5 0.0 0.0062 16.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 ABX12188.1 - 0.0027 16.5 0.2 0.0034 16.2 0.1 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.1 ABX12188.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2613 PF11021.3 ABX12189.1 - 0.082 12.6 0.3 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF1469 PF07332.6 ABX12189.1 - 0.13 11.9 3.0 0.16 11.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF1011 PF06237.7 ABX12189.1 - 0.19 11.6 1.5 1.7 8.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1011) Met_10 PF02475.11 ABX12190.1 - 1.9e-59 200.6 0.3 2.3e-59 200.3 0.2 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 ABX12190.1 - 2.9e-06 27.3 0.0 9.7e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TRM PF02005.11 ABX12190.1 - 9.6e-06 24.7 0.1 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.8 ABX12190.1 - 6.7e-05 22.1 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 ABX12190.1 - 7.5e-05 23.2 0.0 0.00014 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ABX12190.1 - 0.0001 21.9 0.1 0.00018 21.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ABX12190.1 - 0.00049 19.5 0.1 0.00086 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 ABX12190.1 - 0.0016 18.0 0.1 0.0042 16.6 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 ABX12190.1 - 0.0035 16.7 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_16 PF10294.4 ABX12190.1 - 0.055 12.9 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.7 ABX12190.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.22 ABX12191.1 - 2e-39 135.0 0.7 2.8e-18 66.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 ABX12191.1 - 1.8e-09 37.0 2.3 1.8e-09 37.0 1.6 1.8 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 ABX12191.1 - 2.3e-09 36.4 11.7 5.2e-09 35.3 4.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain SMC_N PF02463.14 ABX12191.1 - 2.3e-08 33.5 6.8 0.001 18.3 0.4 3.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ABX12191.1 - 2.6e-08 34.2 5.4 0.31 10.9 1.0 4.5 3 2 0 4 4 3 3 AAA domain Fer4_6 PF12837.2 ABX12191.1 - 6.3e-08 32.1 5.3 6.3e-08 32.1 3.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 ABX12191.1 - 3.3e-06 27.3 11.2 6.4e-06 26.4 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 ABX12191.1 - 7.8e-06 25.5 3.4 7.8e-06 25.5 2.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.1 ABX12191.1 - 2.6e-05 23.9 11.9 4.9e-05 23.0 8.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain DUF258 PF03193.11 ABX12191.1 - 3.3e-05 23.1 0.2 0.012 14.7 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 ABX12191.1 - 0.00017 21.0 0.2 0.069 12.6 0.0 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain Fer4_10 PF13237.1 ABX12191.1 - 0.00028 20.6 2.2 0.00028 20.6 1.5 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_15 PF13175.1 ABX12191.1 - 0.0011 18.1 0.1 3 6.7 0.0 3.8 2 2 2 4 4 4 1 AAA ATPase domain Fer4_3 PF12798.2 ABX12191.1 - 0.0025 18.2 5.4 0.0025 18.2 3.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain SbcCD_C PF13558.1 ABX12191.1 - 0.0031 17.3 0.5 3.4 7.6 0.1 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Miro PF08477.8 ABX12191.1 - 0.0031 17.9 0.1 0.5 10.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein Fer4_4 PF12800.2 ABX12191.1 - 0.011 15.9 3.2 0.011 15.9 2.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 ABX12191.1 - 0.013 15.4 4.5 0.029 14.3 3.1 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_16 PF13191.1 ABX12191.1 - 0.022 14.7 3.1 0.089 12.7 0.1 2.8 3 1 0 3 3 2 0 AAA ATPase domain Fer4_15 PF13459.1 ABX12191.1 - 0.028 14.9 2.0 0.028 14.9 1.4 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain NB-ARC PF00931.17 ABX12191.1 - 0.028 13.2 1.1 3.5 6.4 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain Fer4_9 PF13187.1 ABX12191.1 - 0.05 13.8 13.6 0.12 12.6 9.5 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 ABX12191.1 - 0.051 14.3 12.5 0.48 11.2 8.7 2.3 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain AAA_14 PF13173.1 ABX12191.1 - 0.067 13.0 0.1 3.8 7.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 ABX12191.1 - 0.072 13.0 1.3 0.88 9.5 0.5 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 ABX12191.1 - 0.073 13.2 0.1 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 ABX12191.1 - 0.14 11.5 0.4 9.5 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 ABX12191.1 - 0.27 10.6 1.5 36 3.6 0.0 3.0 2 1 1 3 3 3 0 AAA-like domain AAA_23 PF13476.1 ABX12191.1 - 0.38 11.0 6.5 11 6.2 1.2 2.9 2 2 0 2 2 2 0 AAA domain Fer4_17 PF13534.1 ABX12191.1 - 1 9.7 8.6 0.22 11.8 0.7 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.1 ABX12191.1 - 5.3 7.5 10.7 25 5.3 6.9 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Peptidase_M17 PF00883.16 ABX12192.1 - 5.4e-115 383.5 0.5 7.6e-115 383.0 0.4 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 ABX12192.1 - 6.9e-19 67.8 1.5 9e-19 67.4 0.1 1.9 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain DUF217 PF02697.9 ABX12193.1 - 0.0012 19.0 0.3 0.0024 18.0 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized ACR, COG1753 DUF4415 PF14384.1 ABX12193.1 - 0.034 14.2 0.0 0.048 13.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4415) RHH_1 PF01402.16 ABX12193.1 - 0.13 12.2 0.3 2.4 8.1 0.2 2.1 1 1 0 1 1 1 0 Ribbon-helix-helix protein, copG family zinc_ribbon_6 PF14599.1 ABX12194.1 - 0.0033 17.1 11.1 0.25 11.1 1.3 2.7 2 2 0 2 2 2 2 Zinc-ribbon T4_baseplate PF12322.3 ABX12194.1 - 0.0045 16.2 1.1 0.53 9.5 0.0 2.1 2 0 0 2 2 2 2 T4 bacteriophage base plate protein zf-HC2 PF13490.1 ABX12194.1 - 0.0093 15.8 1.7 4.4 7.3 0.1 2.7 2 0 0 2 2 2 2 Putative zinc-finger C1_1 PF00130.17 ABX12194.1 - 0.014 15.1 11.5 0.45 10.2 1.8 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4001 PF13165.1 ABX12194.1 - 0.04 13.6 12.0 0.29 10.8 0.2 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4001) DZR PF12773.2 ABX12194.1 - 0.09 12.6 15.6 0.51 10.2 2.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon Stig1 PF04885.8 ABX12194.1 - 0.11 12.6 6.3 3.7 7.7 0.5 2.3 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 DUF4392 PF14336.1 ABX12194.1 - 0.14 10.8 0.0 11 4.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) DNA_RNApol_7kD PF03604.8 ABX12194.1 - 0.19 11.2 18.8 2.2 7.8 3.7 3.0 2 2 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Molybdop_Fe4S4 PF04879.11 ABX12194.1 - 0.2 11.5 9.1 1.5 8.7 0.6 2.2 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain LIM PF00412.17 ABX12194.1 - 0.43 10.6 11.8 2.6 8.1 1.5 2.3 2 0 0 2 2 2 0 LIM domain DUF1059 PF06348.6 ABX12194.1 - 0.64 9.8 2.8 19 5.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) CpXC PF14353.1 ABX12194.1 - 1.2 9.0 5.4 13 5.7 0.3 2.3 2 0 0 2 2 2 0 CpXC protein Cytochrom_c3_2 PF14537.1 ABX12194.1 - 1.7 9.0 9.4 3.3 8.1 6.4 1.7 1 1 0 1 1 1 0 Cytochrome c3 Elf1 PF05129.8 ABX12194.1 - 2.7 7.7 11.1 3.3 7.4 0.5 2.8 2 2 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C3HC4_2 PF13923.1 ABX12194.1 - 5.5 7.0 9.2 38 4.4 0.0 3.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.5 ABX12194.1 - 6.2 6.8 19.4 7.1 6.6 3.8 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Hepcidin PF06446.7 ABX12194.1 - 7.5 7.0 14.6 4 7.9 2.5 2.7 3 1 0 3 3 2 0 Hepcidin Transketolase_N PF00456.16 ABX12195.1 - 6e-63 212.6 0.6 2.1e-61 207.6 0.4 2.2 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Ribul_P_3_epim PF00834.14 ABX12195.1 - 6.8e-51 172.2 0.2 9.9e-51 171.7 0.2 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family DXP_synthase_N PF13292.1 ABX12195.1 - 2.1e-06 26.8 0.1 2.9e-05 23.1 0.0 2.6 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 ABX12195.1 - 2.2e-05 23.3 0.0 3.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 ABX12195.1 - 5.5e-05 22.7 0.0 0.00013 21.6 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.5 ABX12195.1 - 0.0016 17.0 1.1 0.0032 16.1 0.1 1.9 2 0 0 2 2 2 1 XFP N-terminal domain Transket_pyr PF02779.19 ABX12196.1 - 6.1e-30 104.0 0.0 8.5e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 ABX12196.1 - 8e-30 103.3 0.1 1.4e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transaldolase PF00923.14 ABX12197.1 - 1.8e-63 214.3 0.0 4.8e-63 212.9 0.0 1.6 1 1 0 1 1 1 1 Transaldolase HATPase_c PF02518.21 ABX12198.1 - 0.2 11.3 0.8 0.26 11.0 0.5 1.4 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CorA PF01544.13 ABX12199.1 - 4.1e-74 249.2 4.2 4.8e-74 249.0 2.9 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ras_bdg_2 PF14847.1 ABX12199.1 - 0.081 12.8 0.4 0.27 11.1 0.0 2.0 3 0 0 3 3 3 0 Ras-binding domain of Byr2 DUF1839 PF08893.5 ABX12199.1 - 0.11 11.4 0.0 0.23 10.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1839) DUF2397 PF09660.5 ABX12199.1 - 0.13 10.8 0.6 0.19 10.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF3566 PF12089.3 ABX12199.1 - 0.16 12.0 0.1 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) CesA PF11439.3 ABX12199.1 - 2 8.4 7.2 1.6 8.7 0.3 3.0 2 1 1 3 3 3 0 Type III secretion system filament chaperone CesA DOT1 PF08123.8 ABX12202.1 - 0.00023 20.5 1.4 0.013 14.8 0.3 2.6 2 2 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 ABX12202.1 - 0.0032 17.0 1.9 0.0069 15.9 1.3 1.6 1 1 0 1 1 1 1 Methyltransferase domain DUF3585 PF12130.3 ABX12202.1 - 0.0079 16.0 0.5 0.013 15.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) Methyltransf_25 PF13649.1 ABX12202.1 - 0.019 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CUB PF00431.15 ABX12202.1 - 0.02 14.9 0.5 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 CUB domain Methyltransf_11 PF08241.7 ABX12202.1 - 0.034 14.6 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 ABX12202.1 - 0.09 13.3 0.1 0.15 12.6 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain UPF0147 PF03685.8 ABX12203.1 - 7.1e-34 115.5 1.9 7.9e-34 115.4 1.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) B5 PF03484.10 ABX12203.1 - 0.022 14.5 0.1 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetase B5 domain DUF1840 PF08895.6 ABX12203.1 - 0.023 14.7 0.3 0.036 14.0 0.1 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) UvrB PF12344.3 ABX12203.1 - 0.05 13.1 1.3 2.3 7.8 0.1 2.3 2 0 0 2 2 2 0 Ultra-violet resistance protein B DUF3461 PF11944.3 ABX12203.1 - 0.055 13.3 0.1 0.48 10.2 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) UPF0253 PF06786.7 ABX12203.1 - 0.12 12.5 0.0 6.3 6.9 0.0 2.2 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0253) Rieske PF00355.21 ABX12204.1 - 8.8e-18 63.6 0.0 1e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 ABX12204.1 - 1.5e-08 34.2 0.0 1.8e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Acetyltransf_1 PF00583.19 ABX12205.1 - 4.2e-07 29.9 0.0 7.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ABX12205.1 - 3.2e-05 23.9 0.0 7.8e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain TaqI_C PF12950.2 ABX12205.1 - 0.0015 18.2 1.1 0.0033 17.1 0.8 1.8 1 1 0 1 1 1 1 TaqI-like C-terminal specificity domain PP2 PF14299.1 ABX12205.1 - 0.0044 16.4 0.0 0.0095 15.3 0.0 1.6 1 0 0 1 1 1 1 Phloem protein 2 FAA_hydrolase PF01557.13 ABX12206.1 - 6.7e-68 228.4 0.0 8.6e-68 228.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.4 ABX12206.1 - 0.002 18.4 0.0 0.012 16.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2437) tRNA-synt_1c PF00749.16 ABX12207.1 - 8.4e-81 271.0 0.0 1.7e-80 270.0 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 ABX12207.1 - 6.3e-26 91.0 2.4 6.4e-26 91.0 0.1 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Syntaxin PF00804.20 ABX12207.1 - 1 9.5 6.9 0.46 10.6 0.6 3.1 3 0 0 3 3 3 0 Syntaxin polyprenyl_synt PF00348.12 ABX12208.1 - 6.1e-69 231.7 0.1 7.9e-69 231.3 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 ABX12208.1 - 0.013 14.7 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain NUDIX PF00293.23 ABX12209.1 - 9.4e-12 44.7 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain AA_kinase PF00696.23 ABX12210.1 - 1.2e-29 103.5 0.0 1.4e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family DUF1967 PF09269.6 ABX12210.1 - 0.013 15.1 0.0 0.3 10.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) GHMP_kinases_N PF00288.21 ABX12211.1 - 8.3e-21 73.8 0.4 2e-20 72.6 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ABX12211.1 - 1.7e-11 44.1 0.0 3.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 ABX12211.1 - 0.082 12.1 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Ribosomal_S2 PF00318.15 ABX12212.1 - 7.3e-35 120.1 0.2 1.8e-17 63.2 0.4 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 AP_endonuc_2 PF01261.19 ABX12212.1 - 0.044 13.0 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Enolase_C PF00113.17 ABX12213.1 - 1.6e-58 198.0 0.1 2.3e-58 197.5 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 ABX12213.1 - 2.7e-26 92.0 0.0 5.4e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain CW_binding_2 PF04122.7 ABX12213.1 - 9.2e-05 22.5 0.5 0.00064 19.8 0.4 2.4 2 0 0 2 2 2 1 Putative cell wall binding repeat 2 RNA_pol_N PF01194.12 ABX12214.1 - 4.2e-29 100.3 0.6 5.4e-29 100.0 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit PhaP_Bmeg PF09602.5 ABX12214.1 - 0.065 13.0 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Chordopox_RPO7 PF05864.7 ABX12214.1 - 0.16 12.0 1.2 0.43 10.6 0.8 1.7 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Translin PF01997.11 ABX12215.1 - 1.6e-31 109.4 4.3 2.1e-31 109.1 3.0 1.2 1 0 0 1 1 1 1 Translin family IMD PF08397.6 ABX12215.1 - 0.067 12.4 4.9 2.4 7.4 0.2 2.6 2 1 1 3 3 3 0 IRSp53/MIM homology domain YjeF_N PF03853.10 ABX12216.1 - 1.2e-48 164.8 0.0 1.4e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus Lactamase_B PF00753.22 ABX12217.1 - 4.1e-25 88.5 1.4 5.5e-25 88.1 1.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ABX12217.1 - 1.7e-05 24.4 1.2 2.9e-05 23.7 0.8 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain KAR PF15222.1 ABX12217.1 - 0.13 12.3 0.1 0.53 10.3 0.0 1.9 2 0 0 2 2 2 0 Kidney androgen-regulated DBI_PRT PF02277.12 ABX12218.1 - 3.4e-25 88.8 0.1 4.6e-25 88.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyltransferase SIS PF01380.17 ABX12219.1 - 1e-49 167.4 3.2 1.5e-28 98.9 1.2 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 ABX12219.1 - 1.5e-23 83.2 0.0 2.9e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 ABX12219.1 - 3.1e-20 72.2 0.1 6.2e-16 58.0 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 ABX12219.1 - 1.9e-17 63.1 0.1 1.2e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 ABX12219.1 - 1.3e-08 33.9 0.1 2.4e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 ABX12219.1 - 1.3e-06 28.1 3.2 0.00014 21.6 1.5 3.5 3 1 0 3 3 3 1 SIS domain S4 PF01479.20 ABX12220.1 - 1e-10 40.8 0.2 7.4e-10 38.1 0.0 2.3 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.14 ABX12220.1 - 6.9e-06 26.3 1.2 1e-05 25.8 0.7 1.4 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_S13 PF00416.17 ABX12221.1 - 3.2e-29 101.4 0.0 3.9e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.1 ABX12221.1 - 0.049 13.6 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3841 PF12952.2 ABX12221.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) Herpes_capsid PF06112.6 ABX12221.1 - 1.2 9.2 4.1 1.5 8.8 2.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein HTH_20 PF12840.2 ABX12222.1 - 1.1e-05 25.1 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4423 PF14394.1 ABX12222.1 - 0.00022 20.8 0.1 0.00046 19.7 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_45 PF14947.1 ABX12222.1 - 0.00037 20.2 0.1 0.00056 19.6 0.0 1.3 1 1 0 1 1 1 1 Winged helix-turn-helix HTH_AsnC-type PF13404.1 ABX12222.1 - 0.0021 17.5 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 ABX12222.1 - 0.0044 16.3 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 ABX12222.1 - 0.0083 15.7 0.2 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_9 PF08221.6 ABX12222.1 - 0.0096 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain Cullin_Nedd8 PF10557.4 ABX12222.1 - 0.025 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Cullin protein neddylation domain TrmB PF01978.14 ABX12222.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB EMP24_GP25L PF01105.19 ABX12223.1 - 0.0011 18.7 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD A2M_N PF01835.14 ABX12223.1 - 0.053 13.7 0.1 0.14 12.4 0.0 1.8 1 1 0 1 1 1 0 MG2 domain DUF2371 PF10177.4 ABX12223.1 - 0.099 12.5 1.1 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) TroA PF01297.12 ABX12224.1 - 1.3e-73 247.4 0.1 1.5e-73 247.2 0.1 1.0 1 0 0 1 1 1 1 Periplasmic solute binding protein family Spheroidin PF05541.7 ABX12224.1 - 0.029 12.0 0.1 0.037 11.6 0.0 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein ABC_tran PF00005.22 ABX12225.1 - 6.2e-32 110.7 0.0 1.2e-31 109.8 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 ABX12225.1 - 3e-11 43.8 0.1 3.8e-05 23.8 0.1 2.2 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 ABX12225.1 - 7.8e-07 28.5 1.2 9.4e-05 21.7 0.8 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ABX12225.1 - 1.3e-06 28.9 0.2 3.6e-06 27.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ABX12225.1 - 1.8e-05 24.2 0.0 0.00026 20.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ABX12225.1 - 3.3e-05 23.3 0.0 7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ABX12225.1 - 4.5e-05 23.5 0.1 0.0019 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 ABX12225.1 - 9e-05 21.7 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 ABX12225.1 - 0.00025 20.2 0.0 0.0014 17.7 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 ABX12225.1 - 0.00085 20.1 0.4 0.0025 18.6 0.3 2.0 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ABX12225.1 - 0.001 18.8 0.1 0.27 10.8 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 ABX12225.1 - 0.0024 17.6 0.9 0.024 14.3 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 ABX12225.1 - 0.0036 17.2 0.5 0.0072 16.2 0.3 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 ABX12225.1 - 0.0053 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 ABX12225.1 - 0.0092 16.4 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_18 PF13238.1 ABX12225.1 - 0.0098 16.1 0.2 0.23 11.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 ABX12225.1 - 0.011 15.6 0.2 0.16 11.8 0.1 2.4 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 ABX12225.1 - 0.011 14.3 0.0 0.021 13.4 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_22 PF13401.1 ABX12225.1 - 0.014 15.5 0.2 0.036 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 ABX12225.1 - 0.019 14.4 0.1 0.038 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 ABX12225.1 - 0.022 13.6 0.1 0.053 12.3 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain MutS_V PF00488.16 ABX12225.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 MutS domain V AAA PF00004.24 ABX12225.1 - 0.034 14.3 0.7 0.12 12.5 0.5 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Phage_int_SAM_1 PF02899.12 ABX12225.1 - 0.036 14.2 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain ATP_bind_1 PF03029.12 ABX12225.1 - 0.039 13.5 0.5 0.78 9.2 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 ABX12225.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ABX12225.1 - 0.052 12.6 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 ABX12225.1 - 0.09 12.3 0.1 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 ABX12225.1 - 0.097 12.4 0.4 0.21 11.4 0.1 1.7 2 0 0 2 2 2 0 Dynamin family Mg_chelatase PF01078.16 ABX12225.1 - 0.097 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Guanylate_kin PF00625.16 ABX12225.1 - 0.11 11.8 0.1 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase NACHT PF05729.7 ABX12225.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 ABX12225.1 - 0.15 11.7 0.4 0.38 10.4 0.1 1.8 2 0 0 2 2 2 0 NTPase ABC-3 PF00950.12 ABX12226.1 - 5.7e-67 225.7 33.1 6.7e-67 225.4 23.0 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.13 ABX12226.1 - 0.00057 18.8 36.0 0.00088 18.1 24.8 1.4 1 1 0 1 1 1 1 FecCD transport family DUF3169 PF11368.3 ABX12226.1 - 0.028 13.6 0.5 0.028 13.6 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) UPF0182 PF03699.8 ABX12226.1 - 0.35 8.7 2.0 0.49 8.2 1.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) ABC-3 PF00950.12 ABX12227.1 - 5.3e-46 156.9 40.8 1.6e-45 155.4 28.3 1.6 1 1 0 1 1 1 1 ABC 3 transport family FecCD PF01032.13 ABX12227.1 - 0.031 13.1 35.7 0.069 11.9 24.6 1.8 1 1 0 1 1 1 0 FecCD transport family Cation_efflux PF01545.16 ABX12228.1 - 2e-77 260.0 24.5 2.9e-62 210.3 5.2 3.0 2 1 1 3 3 3 3 Cation efflux family BON PF04972.12 ABX12228.1 - 0.2 11.4 1.1 0.76 9.5 0.1 2.4 3 0 0 3 3 3 0 BON domain A2M_N PF01835.14 ABX12229.1 - 0.0006 20.0 0.0 0.0095 16.1 0.0 3.1 3 1 0 3 3 3 1 MG2 domain Radical_SAM PF04055.16 ABX12232.1 - 5.8e-12 46.0 0.0 1.1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.14 ABX12232.1 - 0.042 13.7 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 B12 binding domain AIRC PF00731.15 ABX12233.1 - 6.8e-21 74.1 2.4 1.2e-20 73.3 1.6 1.3 1 0 0 1 1 1 1 AIR carboxylase NAD_kinase PF01513.16 ABX12233.1 - 0.0004 19.2 0.1 0.00064 18.5 0.1 1.5 1 1 0 1 1 1 1 ATP-NAD kinase DUF3969 PF13108.1 ABX12233.1 - 0.0083 15.7 0.3 0.017 14.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3969) Hpr_kinase_N PF02603.11 ABX12233.1 - 0.24 11.0 2.0 3.5 7.3 0.4 2.3 2 0 0 2 2 2 0 HPr Serine kinase N terminus Ldh_1_N PF00056.18 ABX12234.1 - 1.9e-36 124.9 0.4 1.9e-36 124.9 0.3 1.7 2 1 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 ABX12234.1 - 6.1e-31 107.4 0.0 9.9e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 ABX12234.1 - 0.14 11.4 1.0 1.1 8.5 0.1 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase DUF111 PF01969.12 ABX12235.1 - 3.4e-119 398.0 0.1 3.9e-119 397.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 QueC PF06508.8 ABX12236.1 - 3.8e-09 36.1 0.1 4.1e-07 29.4 0.0 2.4 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 ABX12236.1 - 6.7e-08 31.4 0.0 2e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 tRNA methyl transferase ATP_bind_3 PF01171.15 ABX12236.1 - 1e-07 31.6 0.1 1.6e-06 27.7 0.1 2.5 1 1 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 ABX12236.1 - 1.5e-07 30.5 0.0 2.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 ABX12236.1 - 2.4e-06 27.2 0.1 4.6e-06 26.3 0.1 1.3 1 1 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 ABX12236.1 - 0.00027 20.4 0.1 0.001 18.5 0.0 2.0 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) AAA_24 PF13479.1 ABX12236.1 - 0.011 15.2 0.1 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aminotran_5 PF00266.14 ABX12237.1 - 2.6e-89 299.5 0.3 3e-89 299.3 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 ABX12237.1 - 9.9e-07 28.1 0.0 1.3e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 ABX12237.1 - 2e-05 23.0 0.0 3.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 ABX12237.1 - 4.4e-05 22.6 0.3 0.0003 19.9 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 ABX12237.1 - 0.0012 17.3 0.0 0.0022 16.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF2100 PF09873.4 ABX12237.1 - 0.015 14.7 0.1 3.5 7.0 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2100) Aminotran_3 PF00202.16 ABX12237.1 - 0.036 12.9 0.0 0.71 8.6 0.0 2.4 2 0 0 2 2 2 0 Aminotransferase class-III A2M_N PF01835.14 ABX12239.1 - 6.4e-05 23.1 0.2 0.00013 22.1 0.1 1.5 1 0 0 1 1 1 1 MG2 domain Saf-Nte_pilin PF09460.5 ABX12239.1 - 0.2 11.4 5.3 0.12 12.1 1.2 2.3 2 1 1 3 3 3 0 Saf-pilin pilus formation protein A2M_N PF01835.14 ABX12240.1 - 0.0018 18.4 1.0 0.25 11.6 0.1 2.4 2 0 0 2 2 2 2 MG2 domain DUF4369 PF14289.1 ABX12240.1 - 0.071 13.1 3.8 0.11 12.4 0.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4369) A2M_N PF01835.14 ABX12241.1 - 2.1e-06 27.8 0.1 3.8e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 MG2 domain RNA_pol_Rpb5_C PF01191.14 ABX12242.1 - 1.4e-28 98.2 0.0 1.7e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb2_6 PF00562.23 ABX12243.1 - 2.5e-121 405.0 0.0 3.9e-121 404.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 ABX12243.1 - 9.8e-56 187.8 0.0 1.4e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 ABX12243.1 - 1e-29 102.5 0.0 2.4e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 ABX12243.1 - 5.6e-27 93.3 0.1 1.9e-26 91.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 ABX12243.1 - 1.5e-24 86.4 0.0 3.7e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 ABX12243.1 - 4.6e-14 51.9 0.1 1.5e-13 50.3 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 ABX12243.1 - 9.7e-12 44.6 0.5 2e-11 43.6 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.2 ABX12243.1 - 0.057 13.2 0.2 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_L37e PF01907.14 ABX12243.1 - 0.18 11.5 0.7 0.47 10.2 0.5 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e OrfB_Zn_ribbon PF07282.6 ABX12243.1 - 0.32 10.6 1.6 0.75 9.4 0.6 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RecR PF02132.10 ABX12243.1 - 0.66 9.4 2.1 8.1 5.9 0.3 2.4 2 0 0 2 2 2 0 RecR protein RNA_pol_Rpb1_5 PF04998.12 ABX12244.1 - 1.2e-84 283.8 2.3 2.3e-84 282.9 1.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 ABX12244.1 - 1.2e-82 277.8 0.8 5.4e-81 272.4 0.1 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 ABX12244.1 - 1.6e-69 233.1 0.0 3.6e-69 231.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 ABX12244.1 - 5.8e-34 117.0 0.0 2.8e-33 114.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 ABX12244.1 - 4.6e-24 84.2 0.0 8.4e-23 80.1 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Lumazine_bd PF12870.2 ABX12244.1 - 0.012 15.6 0.3 0.037 14.0 0.2 1.8 1 0 0 1 1 1 0 Lumazine-binding domain Spore_III_AF PF09581.5 ABX12244.1 - 0.044 13.6 6.1 0.02 14.7 1.7 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) UPF0547 PF10571.4 ABX12244.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 TniQ PF06527.6 ABX12244.1 - 0.22 11.6 0.0 2.2 8.5 0.0 2.2 2 0 0 2 2 2 0 TniQ LSM PF01423.17 ABX12245.1 - 6.9e-18 63.9 0.3 8.5e-18 63.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain A2M_N PF01835.14 ABX12246.1 - 0.017 15.3 0.0 0.27 11.4 0.0 2.5 2 0 0 2 2 2 0 MG2 domain TPR_11 PF13414.1 ABX12247.1 - 3.4e-15 55.4 0.1 2.9e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ABX12247.1 - 7.4e-12 44.2 0.1 0.0053 16.5 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 ABX12247.1 - 1.8e-11 43.1 0.6 0.0012 18.3 1.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ABX12247.1 - 1.2e-09 37.2 0.8 0.0073 16.0 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 ABX12247.1 - 6.6e-08 32.3 0.0 0.00029 20.7 0.1 3.0 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ABX12247.1 - 1e-07 32.3 0.0 4.1e-06 27.3 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ABX12247.1 - 1.1e-07 31.4 3.6 0.0039 17.2 1.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ABX12247.1 - 4.1e-07 30.2 0.6 1.3e-05 25.4 0.9 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ABX12247.1 - 2.8e-06 27.4 0.0 0.056 14.0 0.1 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat Mitofilin PF09731.4 ABX12247.1 - 0.0011 17.6 16.1 0.0015 17.2 11.2 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein TPR_5 PF12688.2 ABX12247.1 - 0.0014 18.6 0.1 0.0093 16.0 0.1 2.2 1 1 1 2 2 2 1 Tetratrico peptide repeat NARP1 PF12569.3 ABX12247.1 - 0.022 13.5 12.8 0.62 8.7 0.0 3.2 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_7 PF13176.1 ABX12247.1 - 0.047 13.5 0.0 8.9 6.3 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 ABX12247.1 - 0.28 11.1 1.2 0.55 10.2 0.8 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF966 PF06136.8 ABX12247.1 - 1.6 8.0 22.8 0.023 14.1 10.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF966) LMBR1 PF04791.11 ABX12247.1 - 4.3 5.8 5.6 5.4 5.4 3.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribosomal_L7Ae PF01248.21 ABX12248.1 - 4e-15 55.0 0.3 4.8e-15 54.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Fijivirus_P9-2 PF06837.6 ABX12248.1 - 0.068 12.2 0.5 0.085 11.9 0.3 1.3 1 1 0 1 1 1 0 Fijivirus P9-2 protein Kinase-PPPase PF03618.9 ABX12248.1 - 0.085 12.3 0.4 0.11 11.9 0.2 1.3 1 1 0 1 1 1 0 Kinase/pyrophosphorylase KH_2 PF07650.12 ABX12249.1 - 1.9e-20 72.1 1.7 1.6e-12 46.8 0.1 2.1 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 ABX12249.1 - 1.8e-12 46.7 0.5 4.4e-06 26.2 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 ABX12249.1 - 1.5e-08 34.2 3.1 4.9e-08 32.6 0.2 2.1 2 0 0 2 2 2 1 NusA-like KH domain KH_1 PF00013.24 ABX12249.1 - 1.2e-05 24.8 1.1 0.0089 15.6 0.0 2.5 2 0 0 2 2 2 2 KH domain DUF310 PF03750.8 ABX12249.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF310) Ribosom_S12_S23 PF00164.20 ABX12250.1 - 8.5e-39 131.7 0.3 1e-38 131.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S7 PF00177.16 ABX12251.1 - 7e-39 132.7 0.6 1e-38 132.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CxxCxxCC PF03692.10 ABX12253.1 - 4e-08 33.6 0.2 1.3e-07 31.9 0.2 1.8 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Acetyltransf_1 PF00583.19 ABX12254.1 - 2.7e-16 59.3 0.0 3.6e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ABX12254.1 - 2.7e-11 43.4 0.0 3.5e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ABX12254.1 - 2.4e-09 37.3 0.0 2.7e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ABX12254.1 - 5.1e-09 36.2 0.0 6.5e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ABX12254.1 - 3.3e-07 30.3 0.0 6.6e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ABX12254.1 - 1.4e-06 28.4 0.0 1.7e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ABX12254.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 ABX12254.1 - 0.00025 20.8 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ABX12254.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Trp_halogenase PF04820.9 ABX12255.1 - 2.6e-05 23.0 0.0 8.2e-05 21.4 0.0 1.6 1 1 0 1 1 1 1 Tryptophan halogenase Nitroreductase PF00881.19 ABX12256.1 - 2.4e-34 118.5 0.0 3.3e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.1 ABX12256.1 - 0.045 12.9 0.0 0.21 10.7 0.0 2.0 2 1 0 2 2 2 0 Putative TM nitroreductase ACP PF06857.6 ABX12257.1 - 0.0059 16.5 0.0 0.0064 16.3 0.0 1.1 1 0 0 1 1 1 1 Malonate decarboxylase delta subunit (MdcD) Rtf2 PF04641.7 ABX12258.1 - 0.029 13.5 1.6 0.028 13.6 1.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger NMD3 PF04981.8 ABX12258.1 - 0.037 13.1 0.9 0.046 12.8 0.6 1.2 1 0 0 1 1 1 0 NMD3 family zf-like PF04071.7 ABX12258.1 - 0.043 13.5 0.6 0.052 13.2 0.4 1.2 1 0 0 1 1 1 0 Cysteine-rich small domain zf-UBP PF02148.14 ABX12258.1 - 0.045 13.8 0.3 0.059 13.4 0.2 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein PHD_2 PF13831.1 ABX12258.1 - 0.1 11.9 2.9 0.42 9.9 0.1 2.2 2 0 0 2 2 2 0 PHD-finger DUF725 PF05267.7 ABX12258.1 - 0.12 12.2 0.9 0.13 12.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF725) OrfB_Zn_ribbon PF07282.6 ABX12258.1 - 0.16 11.6 2.2 0.23 11.1 0.6 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain NinG PF05766.7 ABX12258.1 - 0.16 11.6 2.7 0.2 11.4 1.9 1.0 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein zf-DNL PF05180.7 ABX12258.1 - 0.21 11.3 1.1 0.31 10.8 0.8 1.4 1 1 0 1 1 1 0 DNL zinc finger PHD PF00628.24 ABX12258.1 - 1.1 9.0 5.8 9.1 6.0 4.0 2.1 1 1 0 1 1 1 0 PHD-finger Prim_Zn_Ribbon PF08273.7 ABX12258.1 - 1.1 9.4 4.8 1 9.4 0.1 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase DUF3268 PF11672.3 ABX12258.1 - 1.2 9.2 4.1 3.9 7.6 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3268) DUF3437 PF11919.3 ABX12259.1 - 1.1 8.9 0.0 1.1 8.9 0.0 3.8 3 1 2 5 5 5 0 Domain of unknown function (DUF3437) DUF2670 PF10875.3 ABX12261.1 - 0.033 14.2 0.0 0.038 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) UDG PF03167.14 ABX12262.1 - 3.2e-31 107.8 0.0 4.3e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily tRNA-synt_1 PF00133.17 ABX12263.1 - 6e-62 209.4 1.4 1.9e-60 204.5 1.0 2.4 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 ABX12263.1 - 1.1e-24 86.8 0.5 3.2e-12 45.8 0.0 3.5 2 1 1 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 ABX12263.1 - 1.9e-22 79.6 0.8 3.8e-22 78.6 0.6 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 ABX12263.1 - 5e-11 42.2 7.1 3.2e-07 29.7 0.0 3.4 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 ABX12263.1 - 2.6e-08 33.3 0.3 9.8e-08 31.5 0.0 2.0 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 Nse4-Nse3_bdg PF15412.1 ABX12263.1 - 0.053 13.3 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE V-SNARE PF05008.10 ABX12263.1 - 7 6.8 8.2 12 6.1 1.1 2.8 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus tRNA-synt_2c PF01411.14 ABX12264.1 - 2.6e-78 263.6 0.0 2.6e-78 263.6 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 ABX12264.1 - 9.1e-15 54.2 1.1 9.1e-15 54.2 0.8 2.2 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 ABX12264.1 - 7.5e-08 31.9 3.1 1.8e-07 30.7 2.2 1.7 1 0 0 1 1 1 1 DHHA1 domain YolD PF08863.5 ABX12264.1 - 0.017 14.9 0.4 0.12 12.2 0.1 2.6 2 0 0 2 2 2 0 YolD-like protein ADH_N PF08240.7 ABX12265.1 - 3.6e-23 81.3 0.1 7.9e-23 80.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ABX12265.1 - 4.5e-05 22.9 0.0 0.00028 20.4 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 ABX12265.1 - 0.015 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 ABX12265.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding UPF0444 PF15475.1 ABX12265.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 GSDH PF07995.6 ABX12267.1 - 3.3e-89 299.2 0.2 4e-89 298.9 0.1 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 ABX12267.1 - 0.0076 16.1 0.0 0.4 10.7 0.0 2.8 2 0 0 2 2 2 1 NHL repeat HATPase_c PF02518.21 ABX12268.1 - 4.1e-21 74.7 0.0 8.9e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ABX12268.1 - 2e-12 46.9 0.2 1.4e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 ABX12268.1 - 4.4e-10 39.1 1.2 1.6e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 GHKL domain DUF3068 PF11271.3 ABX12268.1 - 3.4e-09 36.1 2.0 1.1e-08 34.5 1.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3068) HATPase_c_2 PF13581.1 ABX12268.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Baculo_PEP_C PF04513.7 ABX12268.1 - 0.023 14.5 1.1 0.045 13.5 0.8 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_11_kDa PF06143.6 ABX12268.1 - 0.027 13.8 2.3 0.18 11.1 0.3 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family COX2_TM PF02790.10 ABX12268.1 - 7 6.6 8.1 0.36 10.7 0.3 2.6 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain Ribosomal_60s PF00428.14 ABX12270.1 - 9.5e-14 51.5 20.6 1.1e-13 51.3 14.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein UPF0126 PF03458.8 ABX12271.1 - 8.6e-42 140.6 24.9 8.3e-21 73.4 5.7 2.3 2 0 0 2 2 2 2 UPF0126 domain DUF3353 PF11833.3 ABX12271.1 - 7.4 5.9 6.3 0.74 9.2 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Response_reg PF00072.19 ABX12272.1 - 1.8e-23 82.6 0.5 2.1e-23 82.4 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain bZIP_1 PF00170.16 ABX12273.1 - 0.00072 19.4 4.0 0.00072 19.4 2.8 3.7 3 2 0 3 3 3 1 bZIP transcription factor GDE_C PF06202.9 ABX12273.1 - 0.01 14.6 1.3 0.015 14.0 0.9 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase PIG-P PF08510.7 ABX12273.1 - 0.013 15.1 0.7 0.036 13.6 0.0 2.0 2 0 0 2 2 2 0 PIG-P TerB PF05099.8 ABX12273.1 - 0.055 13.2 0.3 0.055 13.2 0.2 2.4 2 1 1 3 3 3 0 Tellurite resistance protein TerB Bac_DNA_binding PF00216.16 ABX12273.1 - 0.11 12.5 2.1 3.4 7.7 0.2 2.5 2 0 0 2 2 2 0 Bacterial DNA-binding protein YlqD PF11068.3 ABX12273.1 - 0.11 12.5 18.1 2.2 8.3 0.8 3.3 2 1 1 3 3 3 0 YlqD protein BLOC1_2 PF10046.4 ABX12273.1 - 0.28 11.3 16.4 0.39 10.8 0.9 3.5 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1128 PF06569.6 ABX12273.1 - 0.45 10.2 10.9 0.19 11.4 1.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1128) DUF972 PF06156.8 ABX12273.1 - 0.6 10.4 15.2 1.4 9.3 0.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF1488 PF07369.6 ABX12273.1 - 0.95 9.3 6.5 0.38 10.6 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) V_ATPase_I PF01496.14 ABX12273.1 - 1.2 6.9 20.3 2.8 5.6 14.1 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 ABX12273.1 - 2 7.8 10.1 2.4 7.5 2.9 2.7 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF4407 PF14362.1 ABX12273.1 - 2.4 7.0 8.8 1.7 7.5 3.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3373 PF11853.3 ABX12273.1 - 3.2 6.1 5.8 8.6 4.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) DivIC PF04977.10 ABX12273.1 - 4.1 6.9 17.7 0.15 11.5 2.0 3.5 3 1 0 3 3 3 0 Septum formation initiator TRCF PF03461.10 ABX12273.1 - 6.2 6.8 13.5 2.5 8.1 0.6 3.7 2 1 1 3 3 3 0 TRCF domain Ax_dynein_light PF10211.4 ABX12273.1 - 6.7 6.5 22.3 1.4 8.7 1.1 3.1 3 0 0 3 3 3 0 Axonemal dynein light chain GldM_N PF12081.3 ABX12273.1 - 8 5.9 14.0 0.73 9.3 0.1 3.4 3 1 1 4 4 4 0 GldM N-terminal domain Zn_Tnp_IS1595 PF12760.2 ABX12275.1 - 0.0064 16.2 0.5 0.014 15.2 0.4 1.6 1 0 0 1 1 1 1 Transposase zinc-ribbon domain TFIIS_C PF01096.13 ABX12275.1 - 0.11 12.1 1.8 5 6.8 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2072 PF09845.4 ABX12275.1 - 0.12 12.2 0.2 0.12 12.2 0.1 2.3 1 1 2 3 3 3 0 Zn-ribbon containing protein (DUF2072) Lar_restr_allev PF14354.1 ABX12275.1 - 0.21 11.9 1.2 0.41 10.9 0.8 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar Fer4 PF00037.22 ABX12275.1 - 0.97 9.1 2.9 13 5.6 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Desulfoferrod_N PF06397.7 ABX12275.1 - 1.6 8.1 4.0 4.8 6.6 0.4 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF1614 PF07758.6 ABX12276.1 - 0.00045 20.0 2.6 0.0032 17.2 0.1 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1614) DUF3366 PF11846.3 ABX12276.1 - 0.039 13.8 0.2 0.077 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) PDGLE PF13190.1 ABX12276.1 - 0.05 13.2 0.1 0.95 9.1 0.1 2.8 1 1 0 1 1 1 0 PDGLE domain DUF2273 PF10031.4 ABX12276.1 - 0.73 9.4 0.0 0.73 9.4 0.0 4.0 4 0 0 4 4 4 0 Small integral membrane protein (DUF2273) Pam17 PF08566.5 ABX12276.1 - 2.4 7.8 6.4 3.4 7.3 0.2 3.2 2 2 1 3 3 3 0 Mitochondrial import protein Pam17 Ribosomal_L10 PF00466.15 ABX12277.1 - 5.7e-19 67.8 1.8 1.3e-18 66.7 1.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L10 SUKH_5 PF14567.1 ABX12277.1 - 0.024 14.1 0.2 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Amidase_3 PF01520.13 ABX12277.1 - 0.081 12.7 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase DUF2935 PF11155.3 ABX12277.1 - 0.13 12.3 1.6 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF4411 PF14367.1 ABX12277.1 - 0.24 11.1 3.1 0.13 11.9 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) ATP-synt_B PF00430.13 ABX12277.1 - 2.3 8.0 8.9 4.5 7.0 6.2 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Ribosomal_L1 PF00687.16 ABX12278.1 - 7.7e-46 156.1 2.0 9.1e-46 155.9 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family AsnC_trans_reg PF01037.16 ABX12279.1 - 2e-15 56.2 0.1 2.9e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 AsnC family HTH_24 PF13412.1 ABX12279.1 - 9.7e-09 34.4 0.2 1.6e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 ABX12279.1 - 0.00013 21.4 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Ribosomal_S25 PF03297.10 ABX12279.1 - 0.00097 19.1 1.7 0.0047 16.9 0.3 2.1 2 0 0 2 2 2 1 S25 ribosomal protein B-block_TFIIIC PF04182.7 ABX12279.1 - 0.0016 18.2 0.1 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 ABX12279.1 - 0.0034 17.0 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.17 ABX12279.1 - 0.0046 16.6 0.1 0.0081 15.8 0.1 1.4 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 ABX12279.1 - 0.017 14.8 0.1 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 ABX12279.1 - 0.053 13.1 1.1 0.13 11.9 0.1 2.1 3 0 0 3 3 3 0 HTH domain HTH_psq PF05225.11 ABX12279.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_27 PF13463.1 ABX12279.1 - 0.097 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.15 ABX12279.1 - 0.12 12.5 0.2 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator MotA_activ PF09114.5 ABX12279.1 - 0.13 11.9 1.2 0.25 11.1 0.1 2.0 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LMSTEN PF07988.7 ABX12280.1 - 0.043 13.1 0.9 1.3 8.3 0.1 2.1 1 1 1 2 2 2 0 LMSTEN motif Cactin_mid PF10312.4 ABX12280.1 - 0.064 12.5 0.2 0.067 12.4 0.1 1.0 1 0 0 1 1 1 0 Conserved mid region of cactin DapB_C PF05173.9 ABX12280.1 - 0.082 12.6 0.0 0.082 12.6 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus Ribosomal_L11_N PF03946.9 ABX12281.1 - 3.3e-24 84.1 0.7 7.4e-24 82.9 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 ABX12281.1 - 4.7e-19 68.2 1.4 7.3e-19 67.6 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Spt5-NGN PF03439.8 ABX12282.1 - 2.1e-20 72.2 0.0 3.6e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 ABX12282.1 - 1.4e-06 27.7 0.1 3.2e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 KOW motif NusG PF02357.14 ABX12282.1 - 0.0027 17.8 0.0 0.0097 16.1 0.0 1.9 1 1 0 1 1 1 1 Transcription termination factor nusG tRNA_deacylase PF04414.7 ABX12283.1 - 3e-63 212.7 0.0 3.7e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase DNA_binding_1 PF01035.15 ABX12284.1 - 3.4e-29 100.4 0.0 3.9e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain IceA2 PF05862.6 ABX12284.1 - 0.063 13.0 0.8 6.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein Glyoxalase_2 PF12681.2 ABX12285.1 - 5.4e-17 62.3 0.0 6.2e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 ABX12285.1 - 7.8e-16 58.2 0.0 9.2e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 ABX12285.1 - 2.4e-09 37.1 0.0 1.8e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 ABX12285.1 - 0.003 17.5 0.0 0.068 13.0 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase-like domain Ribosomal_L19e PF01280.15 ABX12286.1 - 5.4e-43 146.2 11.1 6.2e-43 146.0 7.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e Fe_hyd_SSU PF02256.12 ABX12286.1 - 0.0032 17.4 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit FoP_duplication PF13865.1 ABX12286.1 - 2.3 8.7 6.8 4.9 7.6 4.7 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_L32e PF01655.13 ABX12287.1 - 9e-37 125.4 0.1 1.1e-36 125.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 PEPCK_ATP PF01293.15 ABX12288.1 - 8.8e-214 710.2 0.0 1e-213 710.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Peptidase_S8 PF00082.17 ABX12289.1 - 1.1e-61 208.5 0.3 1.4e-61 208.1 0.2 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 ABX12289.1 - 1.5e-10 40.6 0.0 6.6e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 PA domain Sod_Fe_C PF02777.13 ABX12290.1 - 2.1e-43 146.4 0.2 3.4e-43 145.7 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 ABX12290.1 - 3.5e-29 100.8 0.5 3.5e-29 100.8 0.3 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Prefoldin PF02996.12 ABX12291.1 - 1.1e-17 63.7 6.1 1.6e-17 63.2 2.1 2.1 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 ABX12291.1 - 6.7e-05 22.5 4.2 0.00099 18.8 0.3 2.2 2 0 0 2 2 2 1 Prefoldin subunit Pex19 PF04614.7 ABX12291.1 - 0.0004 20.0 0.5 0.0004 20.0 0.3 2.1 2 0 0 2 2 2 1 Pex19 protein family DUF948 PF06103.6 ABX12291.1 - 0.016 15.0 1.0 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CALCOCO1 PF07888.6 ABX12291.1 - 0.02 13.2 1.0 0.027 12.7 0.7 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like SF-assemblin PF06705.6 ABX12291.1 - 0.023 13.8 1.5 0.027 13.6 0.1 1.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin FlgN PF05130.7 ABX12291.1 - 0.049 13.8 4.4 0.22 11.7 0.3 2.1 2 0 0 2 2 2 0 FlgN protein TMF_TATA_bd PF12325.3 ABX12291.1 - 0.052 13.2 4.9 0.18 11.5 0.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.6 ABX12291.1 - 0.1 11.2 2.2 0.33 9.5 0.3 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein 4HB_MCP_1 PF12729.2 ABX12291.1 - 0.21 10.9 2.9 0.12 11.6 0.2 1.8 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction CENP-F_leu_zip PF10473.4 ABX12291.1 - 0.23 11.2 5.0 0.36 10.6 0.7 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 ABX12291.1 - 0.26 11.1 4.3 0.75 9.6 0.5 2.1 2 0 0 2 2 2 0 Tropomyosin like Sipho_Gp157 PF05565.6 ABX12291.1 - 0.39 10.2 4.5 0.72 9.4 0.4 2.0 2 0 0 2 2 2 0 Siphovirus Gp157 DUF1840 PF08895.6 ABX12291.1 - 0.4 10.7 3.4 0.51 10.3 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) Snapin_Pallidin PF14712.1 ABX12291.1 - 0.5 10.7 5.0 0.97 9.7 0.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin DUF724 PF05266.9 ABX12291.1 - 0.55 9.8 4.5 0.5 9.9 0.6 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF4200 PF13863.1 ABX12291.1 - 0.61 10.0 6.4 0.32 10.9 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 ABX12291.1 - 0.9 9.1 5.7 2.1 7.9 0.3 2.1 2 0 0 2 2 2 0 IncA protein FliD_C PF07195.7 ABX12291.1 - 1.3 8.2 5.0 1.6 8.0 3.2 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus YjfB_motility PF14070.1 ABX12291.1 - 1.4 8.8 10.4 0.87 9.4 0.8 2.4 2 0 0 2 2 2 0 Putative motility protein Mnd1 PF03962.10 ABX12291.1 - 1.4 8.5 5.4 1.1 8.8 0.8 2.0 2 0 0 2 2 2 0 Mnd1 family Mod_r PF07200.8 ABX12291.1 - 2.9 7.8 6.3 7.7 6.4 0.5 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein eIF3_N PF09440.5 ABX12291.1 - 3.1 7.9 5.5 2.6 8.2 0.7 2.0 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain ATP-synt_B PF00430.13 ABX12291.1 - 6.2 6.6 10.8 0.24 11.2 3.0 1.9 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) FliJ PF02050.11 ABX12291.1 - 8.5 6.4 13.9 2 8.4 0.6 2.4 2 1 0 2 2 2 0 Flagellar FliJ protein V-SNARE PF05008.10 ABX12291.1 - 9.6 6.4 14.2 1.2 9.2 1.6 2.6 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus SRP54 PF00448.17 ABX12292.1 - 2.3e-70 236.0 0.6 3.2e-70 235.5 0.4 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 ABX12292.1 - 4.1e-12 46.0 8.0 9.2e-12 44.9 5.5 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.1 ABX12292.1 - 2.3e-07 30.5 0.1 3.6e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ABX12292.1 - 2.6e-05 24.3 0.0 5.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 ABX12292.1 - 5.4e-05 22.6 0.2 0.00012 21.6 0.1 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Trypan_PARP PF05887.6 ABX12292.1 - 0.00015 21.5 52.9 0.00015 21.5 36.7 3.3 1 1 2 3 3 2 2 Procyclic acidic repetitive protein (PARP) Zeta_toxin PF06414.7 ABX12292.1 - 0.00019 20.5 0.2 0.00031 19.9 0.1 1.2 1 0 0 1 1 1 1 Zeta toxin MobB PF03205.9 ABX12292.1 - 0.0009 18.9 0.1 0.022 14.4 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 ABX12292.1 - 0.001 19.2 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 ABX12292.1 - 0.0013 17.8 0.1 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase cobW PF02492.14 ABX12292.1 - 0.0022 17.4 0.6 0.0061 16.0 0.4 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 ABX12292.1 - 0.0024 17.8 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 ABX12292.1 - 0.0029 17.3 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 ABX12292.1 - 0.0041 16.8 0.7 0.58 9.8 0.5 2.3 1 1 0 1 1 1 1 NTPase Thymidylate_kin PF02223.12 ABX12292.1 - 0.0055 16.1 0.1 0.021 14.1 0.0 2.1 3 0 0 3 3 2 1 Thymidylate kinase KTI12 PF08433.5 ABX12292.1 - 0.0056 15.9 0.6 0.012 14.8 0.0 1.8 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 ABX12292.1 - 0.0061 16.4 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 ABX12292.1 - 0.0061 16.2 0.1 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase SPOUT_MTase PF02590.12 ABX12292.1 - 0.0082 15.8 0.1 0.021 14.5 0.0 1.6 1 1 0 1 1 1 1 Predicted SPOUT methyltransferase DUF2075 PF09848.4 ABX12292.1 - 0.0085 15.0 0.2 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 ABX12292.1 - 0.014 15.0 1.9 0.017 14.7 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 ABX12292.1 - 0.017 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 ABX12292.1 - 0.022 13.5 0.1 0.08 11.7 0.1 1.8 1 1 0 1 1 1 0 ArgK protein PBP1_TM PF14812.1 ABX12292.1 - 0.024 14.9 9.6 0.047 13.9 6.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_28 PF13521.1 ABX12292.1 - 0.029 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TK PF00265.13 ABX12292.1 - 0.044 13.3 0.1 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase AAA_5 PF07728.9 ABX12292.1 - 0.088 12.5 0.1 0.16 11.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.9 ABX12292.1 - 0.16 11.6 0.4 0.32 10.6 0.3 1.5 1 1 0 1 1 1 0 Helicase Nucleoplasmin PF03066.10 ABX12292.1 - 0.51 9.8 13.3 0.89 9.0 9.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 ABX12292.1 - 5.7 7.1 11.5 76 3.5 6.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) OTCace PF00185.19 ABX12293.1 - 3.7e-50 169.8 0.0 6.1e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 ABX12293.1 - 5.3e-49 165.5 0.0 7.4e-49 165.0 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain F420_oxidored PF03807.12 ABX12293.1 - 0.021 15.2 0.1 0.2 12.1 0.0 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 ABX12293.1 - 0.063 13.0 0.3 0.15 11.7 0.2 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus THF_DHG_CYH_C PF02882.14 ABX12293.1 - 0.12 11.4 0.2 0.58 9.2 0.2 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ribosomal_L18p PF00861.17 ABX12294.1 - 1.4e-21 76.8 0.9 1.9e-21 76.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_S5 PF00333.15 ABX12295.1 - 3e-19 68.5 0.4 4.8e-19 67.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 ABX12295.1 - 3.9e-15 54.8 0.1 6.6e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DOMON PF03351.12 ABX12295.1 - 0.08 12.8 0.1 1.4 8.8 0.1 2.3 3 0 0 3 3 3 0 DOMON domain Ribosomal_L30 PF00327.15 ABX12296.1 - 2.6e-13 49.3 0.3 5.6e-13 48.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L18e PF00828.14 ABX12297.1 - 2.2e-18 66.8 0.8 2.8e-18 66.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 SecY PF00344.15 ABX12298.1 - 7.2e-82 275.0 19.7 8.8e-82 274.7 13.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 ABX12298.1 - 1.6e-11 43.4 3.3 7.5e-11 41.3 0.3 2.9 2 0 0 2 2 2 1 Plug domain of Sec61p Phage_holin_5 PF06946.6 ABX12298.1 - 0.031 14.4 0.9 0.2 11.8 0.1 2.6 2 0 0 2 2 2 0 Phage holin AAA_18 PF13238.1 ABX12299.1 - 3.5e-14 53.2 0.1 4.7e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ABX12299.1 - 5.3e-08 33.7 0.0 7.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 ABX12299.1 - 9.3e-08 31.7 0.1 1.4e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_28 PF13521.1 ABX12299.1 - 1.1e-06 28.6 0.0 2.3e-06 27.6 0.0 1.5 2 0 0 2 2 1 1 AAA domain KTI12 PF08433.5 ABX12299.1 - 3.1e-05 23.3 0.1 4.1e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NTPase_1 PF03266.10 ABX12299.1 - 5e-05 23.0 1.3 0.00046 19.9 0.9 2.1 1 1 1 2 2 2 1 NTPase MMR_HSR1 PF01926.18 ABX12299.1 - 9.6e-05 22.3 0.1 0.00016 21.5 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 ABX12299.1 - 0.00023 20.8 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 ABX12299.1 - 0.00027 20.4 0.1 0.00063 19.2 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 ABX12299.1 - 0.0003 20.6 0.1 0.00048 20.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ABX12299.1 - 0.0003 20.8 0.1 0.00049 20.1 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 ABX12299.1 - 0.0007 19.3 0.1 0.0013 18.5 0.1 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 ABX12299.1 - 0.00086 19.5 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 ABX12299.1 - 0.00093 19.0 0.0 0.0012 18.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ABX12299.1 - 0.0012 18.9 0.1 0.0026 17.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 ABX12299.1 - 0.0017 18.8 1.0 0.0025 18.3 0.3 1.7 2 1 0 2 2 1 1 Miro-like protein ArgK PF03308.11 ABX12299.1 - 0.0021 16.9 0.1 0.0032 16.2 0.1 1.3 1 0 0 1 1 1 1 ArgK protein MobB PF03205.9 ABX12299.1 - 0.0026 17.4 0.3 0.0063 16.2 0.2 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 ABX12299.1 - 0.0033 17.1 0.0 0.0075 15.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 ABX12299.1 - 0.0034 17.6 1.0 0.0043 17.3 0.6 1.5 1 1 0 1 1 1 1 ABC transporter ATP_bind_1 PF03029.12 ABX12299.1 - 0.0037 16.8 0.3 0.0082 15.7 0.1 1.6 2 0 0 2 2 1 1 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 ABX12299.1 - 0.0039 16.1 0.1 0.0054 15.6 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain DnaB_C PF03796.10 ABX12299.1 - 0.0039 16.0 0.1 0.0063 15.4 0.1 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DUF258 PF03193.11 ABX12299.1 - 0.0044 16.2 0.3 0.0065 15.6 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_30 PF13604.1 ABX12299.1 - 0.0045 16.5 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ABX12299.1 - 0.0047 16.0 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF2075 PF09848.4 ABX12299.1 - 0.0061 15.5 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Guanylate_kin PF00625.16 ABX12299.1 - 0.013 14.9 0.3 0.026 13.9 0.1 1.6 1 1 0 1 1 1 0 Guanylate kinase Viral_helicase1 PF01443.13 ABX12299.1 - 0.014 14.9 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 ABX12299.1 - 0.015 14.8 0.2 0.064 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 ABX12299.1 - 0.015 14.6 0.3 0.059 12.7 0.0 1.9 1 1 1 2 2 2 0 AAA domain T2SE PF00437.15 ABX12299.1 - 0.018 13.9 0.1 0.034 13.0 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 ABX12299.1 - 0.03 14.5 0.0 0.078 13.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase TrwB_AAD_bind PF10412.4 ABX12299.1 - 0.031 12.8 0.3 0.051 12.1 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.4 ABX12299.1 - 0.036 13.5 0.2 0.1 12.1 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 ABX12299.1 - 0.039 13.0 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Ras PF00071.17 ABX12299.1 - 0.042 13.2 0.1 0.096 12.0 0.1 1.7 1 0 0 1 1 1 0 Ras family KAP_NTPase PF07693.9 ABX12299.1 - 0.046 12.7 0.0 0.049 12.6 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_5 PF07728.9 ABX12299.1 - 0.06 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arf PF00025.16 ABX12299.1 - 0.075 12.2 0.4 0.13 11.4 0.1 1.7 2 1 0 2 2 1 0 ADP-ribosylation factor family FeoB_N PF02421.13 ABX12299.1 - 0.078 12.2 0.1 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_15 PF13175.1 ABX12299.1 - 0.08 11.9 0.2 0.09 11.8 0.2 1.2 1 0 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.12 ABX12299.1 - 0.087 12.1 0.5 0.59 9.4 0.3 2.3 1 1 0 1 1 1 0 Thymidylate kinase SRPRB PF09439.5 ABX12299.1 - 0.094 11.9 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 ABX12299.1 - 0.099 12.0 0.1 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain UPF0079 PF02367.12 ABX12299.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 ABX12299.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF106 PF01956.11 ABX12300.1 - 2.7e-14 53.0 13.1 8.6e-14 51.4 9.1 1.7 1 1 0 1 1 1 1 Integral membrane protein DUF106 Cytidylate_kin2 PF13189.1 ABX12301.1 - 5.4e-15 55.7 0.0 6.9e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.1 ABX12301.1 - 1.6e-13 51.0 0.0 2.8e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ABX12301.1 - 1.5e-11 45.1 0.1 2.6e-11 44.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 ABX12301.1 - 2.3e-08 34.0 0.6 7.6e-08 32.3 0.4 1.7 1 1 0 1 1 1 1 Shikimate kinase ADK PF00406.17 ABX12301.1 - 1.6e-05 24.7 1.0 4.7e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.1 ABX12301.1 - 2.6e-05 24.1 0.0 0.00066 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 ABX12301.1 - 4.3e-05 23.5 0.0 8.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 ABX12301.1 - 0.00016 21.8 0.1 0.00028 21.1 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 ABX12301.1 - 0.0013 18.0 0.1 0.0035 16.5 0.1 1.8 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_14 PF13173.1 ABX12301.1 - 0.0037 17.1 0.2 0.012 15.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 ABX12301.1 - 0.0037 17.4 0.0 0.007 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 ABX12301.1 - 0.0051 16.5 0.0 0.0097 15.6 0.0 1.6 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 ABX12301.1 - 0.0058 16.7 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 ABX12301.1 - 0.0059 16.3 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 NTPase Zeta_toxin PF06414.7 ABX12301.1 - 0.0089 15.1 0.0 0.018 14.1 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 ABX12301.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 ABX12301.1 - 0.018 15.0 0.0 0.023 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.7 ABX12301.1 - 0.022 13.7 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 ABX12301.1 - 0.03 13.0 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 ABX12301.1 - 0.038 13.3 0.0 0.074 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 ABX12301.1 - 0.06 12.7 1.1 1.2 8.5 0.0 2.4 2 1 0 2 2 2 0 Guanylate kinase TruB_N PF01509.13 ABX12302.1 - 7.9e-25 87.7 1.7 3.2e-14 53.3 0.0 3.6 2 1 1 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 ABX12302.1 - 5.6e-18 64.4 0.2 1.1e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 PUA domain DKCLD PF08068.7 ABX12302.1 - 5e-12 45.5 0.0 9.6e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 DKCLD (NUC011) domain FlgD_ig PF13860.1 ABX12303.1 - 1.3e-05 24.7 0.1 3e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 FlgD Ig-like domain DUF104 PF01954.11 ABX12303.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 OapA PF04225.7 ABX12303.1 - 0.11 12.3 0.0 5.2 7.0 0.0 2.2 1 1 1 2 2 2 0 Opacity-associated protein A LysM-like domain SusE PF14292.1 ABX12303.1 - 0.13 12.0 0.1 0.29 10.9 0.1 1.6 1 1 0 1 1 1 0 SusE outer membrane protein DM13 PF10517.4 ABX12304.1 - 5.4e-28 97.5 0.0 6.8e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Electron transfer DM13 DAO PF01266.19 ABX12305.1 - 1.5e-43 149.0 0.0 2.2e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 ABX12305.1 - 4.8e-12 44.8 0.0 5.6e-05 21.4 0.0 2.4 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.1 ABX12305.1 - 4e-06 27.0 0.0 0.00023 21.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ABX12305.1 - 8.5e-06 26.0 3.7 0.024 15.0 0.0 4.2 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ABX12305.1 - 4.3e-05 23.4 0.3 0.00057 19.8 0.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ABX12305.1 - 0.0023 17.9 0.0 0.0065 16.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ABX12305.1 - 0.0024 16.8 0.0 0.071 12.0 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 ABX12305.1 - 0.0072 14.8 1.6 0.44 8.9 0.0 2.5 2 1 1 3 3 3 2 HI0933-like protein Trp_halogenase PF04820.9 ABX12305.1 - 0.051 12.2 0.3 5.8 5.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 ABX12305.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 ABX12305.1 - 0.072 11.9 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 ABX12305.1 - 0.088 12.5 0.1 2.5 7.8 0.1 2.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 ABX12305.1 - 0.15 11.1 0.1 0.9 8.5 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain ChuX_HutX PF06228.8 ABX12307.1 - 3e-07 29.8 0.0 3.7e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX HemS PF05171.7 ABX12307.1 - 0.0063 16.3 0.0 0.0069 16.1 0.0 1.1 1 0 0 1 1 1 1 Haemin-degrading HemS.ChuX domain 2-Hacid_dh_C PF02826.14 ABX12308.1 - 2.1e-65 219.2 0.1 2.9e-65 218.7 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ABX12308.1 - 2.5e-30 104.6 0.0 2.9e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ABX12308.1 - 8.7e-10 38.6 0.2 1.5e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 ABX12308.1 - 2.3e-06 27.0 0.1 4.4e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 ABX12308.1 - 0.00013 22.2 0.0 0.00036 20.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 ABX12308.1 - 0.021 14.8 0.0 0.094 12.7 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain HPPK PF01288.15 ABX12308.1 - 0.079 12.6 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NAD_binding_7 PF13241.1 ABX12308.1 - 0.088 13.0 0.2 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding POR_N PF01855.14 ABX12309.1 - 1.9e-56 191.1 0.0 2.8e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.13 ABX12309.1 - 1.3e-28 100.0 0.0 2.6e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 ABX12309.1 - 7.6e-07 29.1 0.1 2e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain TPP_enzyme_N PF02776.13 ABX12309.1 - 0.0011 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 ABX12310.1 - 4.6e-29 100.9 0.4 7.1e-29 100.3 0.3 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.3 ABX12310.1 - 2.7e-08 33.6 0.4 5.7e-06 26.1 0.3 3.0 1 1 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Prefoldin PF02996.12 ABX12311.1 - 0.074 12.7 0.1 0.24 11.0 0.1 1.7 2 0 0 2 2 2 0 Prefoldin subunit TM1586_NiRdase PF14512.1 ABX12312.1 - 0.055 12.6 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative TM nitroreductase DUF684 PF05075.9 ABX12314.1 - 0.02 13.5 0.3 0.031 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF684) DUF473 PF04322.7 ABX12314.1 - 0.064 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF473) F420_ligase PF01996.11 ABX12315.1 - 5.2e-55 186.0 0.4 5.9e-55 185.8 0.3 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase Aconitase PF00330.15 ABX12316.1 - 1.2e-76 258.0 3.6 2.9e-51 174.4 0.3 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ABX12317.1 - 8.1e-22 77.7 0.1 4.7e-20 72.0 0.0 2.2 1 1 1 2 2 2 2 Aconitase C-terminal domain Aconitase_2_N PF06434.8 ABX12317.1 - 0.0049 16.3 0.2 0.074 12.4 0.0 2.0 1 1 1 2 2 2 1 Aconitate hydratase 2 N-terminus Antitoxin-MazE PF04014.13 ABX12317.1 - 0.034 13.8 0.1 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Antidote-toxin recognition MazE Aconitase PF00330.15 ABX12318.1 - 5.2e-167 556.0 0.0 5.8e-167 555.8 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.8 ABX12318.1 - 0.057 11.9 0.0 0.085 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Aconitase_C PF00694.14 ABX12319.1 - 8.8e-40 135.8 0.0 1.7e-39 134.9 0.0 1.5 2 0 0 2 2 2 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 ABX12319.1 - 0.0012 18.3 0.1 0.027 13.9 0.1 2.1 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus FAD_syn PF06574.7 ABX12319.1 - 0.045 13.3 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase NTP_transferase PF00483.18 ABX12320.1 - 4.4e-20 72.0 0.2 5.1e-20 71.8 0.2 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 ABX12320.1 - 8.6e-12 45.4 0.0 9.6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.14 ABX12320.1 - 0.0029 17.2 0.0 0.0059 16.2 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase IspD PF01128.14 ABX12320.1 - 0.0089 15.5 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Ribosomal_S9 PF00380.14 ABX12321.1 - 8.3e-36 122.9 0.4 9.5e-36 122.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.13 ABX12322.1 - 4.7e-26 91.3 0.1 5.9e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_L18e PF00828.14 ABX12323.1 - 3e-09 37.3 0.1 3.7e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Aconitase_2_N PF06434.8 ABX12323.1 - 0.047 13.0 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus RNA_pol_A_bac PF01000.21 ABX12324.1 - 4.5e-26 91.1 0.0 1.1e-25 89.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 ABX12324.1 - 1.4e-10 40.1 0.0 1.7e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SBDS PF01172.13 ABX12326.1 - 2.1e-24 85.1 0.2 3.9e-24 84.2 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 ABX12326.1 - 7.4e-20 70.9 1.0 1.3e-19 70.1 0.3 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain EFG_C PF00679.19 ABX12326.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G C-terminus KH_1 PF00013.24 ABX12327.1 - 1.4e-12 47.0 0.1 2.9e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 ABX12327.1 - 2.8e-06 26.8 0.0 6.6e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 ABX12327.1 - 9.5e-05 21.8 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 ABX12327.1 - 0.11 12.1 0.0 0.33 10.6 0.0 2.0 1 1 0 1 1 1 0 KH domain RNase_PH PF01138.16 ABX12328.1 - 1.4e-35 122.4 0.0 1.9e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ABX12328.1 - 6.5e-15 54.8 0.4 1.4e-14 53.7 0.3 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.16 ABX12329.1 - 2.9e-24 85.8 0.0 4.9e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ABX12329.1 - 2.3e-13 49.8 0.2 1.6e-12 47.1 0.1 2.3 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Ribosomal_L37ae PF01780.14 ABX12330.1 - 1.1e-19 70.0 3.2 1.2e-19 69.9 2.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 ABX12330.1 - 0.00095 18.9 2.2 0.00095 18.9 1.5 1.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 ABX12330.1 - 0.0073 15.9 2.1 0.013 15.1 1.4 1.6 1 1 0 1 1 1 1 Putative transposase DNA-binding domain C1_1 PF00130.17 ABX12330.1 - 0.024 14.3 1.6 0.037 13.7 1.1 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 ABX12330.1 - 0.034 13.9 1.6 0.06 13.1 1.1 1.4 1 1 0 1 1 1 0 Double zinc ribbon Rep_fac-A_C PF08646.5 ABX12330.1 - 0.042 13.5 1.1 0.046 13.4 0.7 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain GCC2_GCC3 PF07699.8 ABX12330.1 - 0.056 13.0 0.6 0.074 12.6 0.4 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 Zn-ribbon_8 PF09723.5 ABX12330.1 - 0.057 13.3 0.9 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.11 ABX12330.1 - 0.06 13.0 0.1 0.095 12.4 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Prok-RING_1 PF14446.1 ABX12330.1 - 0.061 13.0 0.6 0.09 12.5 0.4 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Fusion_gly_K PF01621.12 ABX12330.1 - 0.079 11.9 0.0 0.092 11.7 0.0 1.0 1 0 0 1 1 1 0 Cell fusion glycoprotein K NOB1_Zn_bind PF08772.6 ABX12330.1 - 0.088 12.6 1.4 0.14 11.9 0.7 1.7 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like TF_Zn_Ribbon PF08271.7 ABX12330.1 - 0.11 11.8 2.5 0.22 10.8 1.7 1.5 1 1 0 1 1 1 0 TFIIB zinc-binding GFA PF04828.9 ABX12330.1 - 0.11 12.3 1.7 0.31 10.9 0.1 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DNA_RNApol_7kD PF03604.8 ABX12330.1 - 0.13 11.7 1.1 9.8 5.7 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-ISL3 PF14690.1 ABX12330.1 - 0.17 11.9 3.0 0.41 10.7 0.1 2.5 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 A2L_zn_ribbon PF08792.5 ABX12330.1 - 0.23 10.9 2.0 7.2 6.2 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 ABX12330.1 - 0.46 9.7 4.0 2.3 7.5 3.0 1.9 1 1 1 2 2 2 0 zinc-ribbon domain Prim_Zn_Ribbon PF08273.7 ABX12330.1 - 0.58 10.2 4.7 1.6 8.8 3.2 1.7 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Pcc1 PF09341.5 ABX12331.1 - 6.9e-07 29.2 0.0 7.7e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF1667 PF07892.6 ABX12331.1 - 0.1 12.3 0.1 0.15 11.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1667) Prefoldin_2 PF01920.15 ABX12332.1 - 1.2e-20 73.2 25.4 1.3e-20 73.0 17.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit FixO PF02433.10 ABX12332.1 - 0.079 12.3 5.1 0.097 12.0 3.5 1.0 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Bac_DNA_binding PF00216.16 ABX12332.1 - 0.18 11.8 5.6 0.22 11.5 1.1 2.1 2 0 0 2 2 2 0 Bacterial DNA-binding protein Gly_radical PF01228.16 ABX12332.1 - 0.29 11.5 1.3 0.58 10.5 0.8 1.7 1 1 0 1 1 1 0 Glycine radical AF0941-like PF14591.1 ABX12332.1 - 0.32 11.0 12.9 4.9 7.2 8.4 2.1 1 1 0 1 1 1 0 AF0941-like DUF3053 PF11254.3 ABX12332.1 - 0.62 9.2 8.0 1.2 8.3 5.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3053) TPR_MLP1_2 PF07926.7 ABX12332.1 - 1 9.0 20.3 1.5 8.6 4.7 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 ABX12332.1 - 1.1 8.8 15.4 1.6 8.3 10.7 1.2 1 0 0 1 1 1 0 IncA protein Peptidase_M3_N PF08439.5 ABX12332.1 - 1.1 9.3 8.9 2.9 7.9 0.3 2.2 2 0 0 2 2 2 0 Oligopeptidase F DUF342 PF03961.8 ABX12332.1 - 1.3 7.3 13.7 1.6 7.0 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sld5 PF05916.6 ABX12332.1 - 1.3 9.3 7.8 3.3 8.0 5.4 1.8 1 1 0 1 1 1 0 GINS complex protein KIP1 PF07765.7 ABX12332.1 - 5 7.0 11.2 16 5.4 1.8 3.0 1 1 2 3 3 3 0 KIP1-like protein DUF4613 PF15390.1 ABX12332.1 - 9.7 4.2 10.0 11 4.0 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) ERCC4 PF02732.10 ABX12333.1 - 5.4e-24 84.5 0.0 1.1e-23 83.5 0.0 1.5 2 0 0 2 2 2 1 ERCC4 domain HHH PF00633.18 ABX12333.1 - 9.8e-08 31.2 0.1 0.0048 16.5 0.1 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 ABX12333.1 - 3e-07 30.5 0.1 7.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 ABX12333.1 - 5.1e-06 26.2 0.0 5.7e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.2 ABX12333.1 - 0.0002 21.2 0.0 0.032 14.1 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_8 PF14716.1 ABX12333.1 - 0.0056 16.8 0.2 0.34 11.1 0.0 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix domain 5_3_exonuc PF01367.15 ABX12333.1 - 0.086 13.0 0.1 0.22 11.7 0.1 1.7 1 1 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_11 PF13414.1 ABX12334.1 - 4.4e-19 67.8 0.0 1.9e-09 37.0 0.0 2.1 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ABX12334.1 - 1.2e-17 62.6 0.0 8.1e-05 22.0 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ABX12334.1 - 7.2e-17 59.8 0.0 2.7e-05 23.7 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 ABX12334.1 - 6.3e-12 45.6 0.3 0.0002 21.6 0.0 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ABX12334.1 - 1.6e-11 44.5 0.0 0.00029 21.4 0.0 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ABX12334.1 - 1.4e-10 40.8 0.0 0.00061 20.1 0.0 3.7 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ABX12334.1 - 2.7e-10 39.2 0.7 0.034 13.9 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ABX12334.1 - 1.7e-09 37.5 0.0 0.081 13.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ABX12334.1 - 3.8e-09 36.3 0.1 0.00075 19.3 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ABX12334.1 - 4.9e-09 35.6 0.1 0.013 15.6 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ABX12334.1 - 2.5e-08 33.9 0.0 0.00048 20.2 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 ABX12334.1 - 3.1e-07 29.6 0.0 0.016 14.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ABX12334.1 - 0.00013 21.7 0.0 0.53 10.1 0.0 2.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 ABX12334.1 - 0.0014 18.5 0.2 0.96 9.4 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 ABX12334.1 - 0.044 12.5 0.0 0.66 8.6 0.0 2.0 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 ABX12334.1 - 0.051 13.7 0.0 0.32 11.1 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 ABX12334.1 - 0.056 13.4 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_15 PF13429.1 ABX12334.1 - 0.13 11.2 0.0 0.7 8.9 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat UPF0278 PF08745.6 ABX12335.1 - 1.8e-06 27.3 0.2 0.00025 20.3 0.1 2.1 2 0 0 2 2 2 2 UPF0278 family PIN PF01850.16 ABX12335.1 - 2e-05 24.8 0.1 2.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 PIN domain RecR PF02132.10 ABX12335.1 - 0.066 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 RecR protein zf-C3HC4_3 PF13920.1 ABX12335.1 - 0.096 12.3 1.7 0.17 11.6 1.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NAD_kinase PF01513.16 ABX12336.1 - 2.2e-37 128.3 1.2 2.6e-37 128.1 0.9 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 ABX12336.1 - 0.0006 19.2 0.2 0.0013 18.1 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CoA_binding_2 PF13380.1 ABX12336.1 - 0.019 15.1 0.0 0.048 13.8 0.0 1.8 1 0 0 1 1 1 0 CoA binding domain Rhodanese PF00581.15 ABX12337.1 - 1e-37 128.9 0.1 1.9e-22 79.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Fer4 PF00037.22 ABX12339.1 - 1e-07 31.2 16.0 0.00031 20.2 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 ABX12339.1 - 4e-06 26.9 5.2 9.3e-06 25.8 3.6 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 ABX12339.1 - 5.8e-06 26.5 4.9 1.8e-05 25.0 3.5 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 ABX12339.1 - 2.4e-05 24.0 5.7 5.3e-05 22.9 3.9 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 ABX12339.1 - 0.0002 21.1 3.2 0.00036 20.3 2.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 ABX12339.1 - 0.00037 20.8 2.0 0.62 10.5 0.4 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 ABX12339.1 - 0.00067 19.4 13.2 0.01 15.6 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 ABX12339.1 - 0.0028 17.6 5.3 0.061 13.3 4.3 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 ABX12339.1 - 0.0041 17.4 1.2 2.2 8.7 0.0 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 ABX12339.1 - 0.031 14.2 11.0 0.29 11.1 0.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.2 ABX12339.1 - 0.14 12.5 5.5 4.1 7.9 0.8 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.2 ABX12339.1 - 0.24 12.0 15.8 0.38 11.4 1.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.1 ABX12339.1 - 1.3 9.6 10.5 2.1 8.9 0.4 3.3 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_16 PF13484.1 ABX12339.1 - 3.2 8.5 9.4 4.9 7.9 1.4 2.8 2 1 1 3 3 2 0 4Fe-4S double cluster binding domain Fer4_13 PF13370.1 ABX12339.1 - 3.9 7.9 8.7 5.5 7.4 0.4 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain Glyco_tranf_2_3 PF13641.1 ABX12340.1 - 6.2e-38 130.8 0.1 8.8e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 ABX12340.1 - 1.2e-22 80.5 0.3 2.8e-22 79.3 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 ABX12340.1 - 4.5e-16 58.9 0.1 7.6e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 ABX12340.1 - 8.3e-14 51.2 0.1 1.5e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 ABX12340.1 - 0.00046 18.6 2.4 0.00078 17.8 0.2 1.9 2 0 0 2 2 2 1 Cellulose synthase DUF2371 PF10177.4 ABX12340.1 - 0.045 13.6 0.0 0.95 9.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Glyco_tranf_2_4 PF13704.1 ABX12340.1 - 0.086 13.1 0.1 0.61 10.4 0.2 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF1664 PF07889.7 ABX12341.1 - 0.00028 20.6 38.0 0.011 15.5 0.8 5.6 1 1 4 6 6 6 2 Protein of unknown function (DUF1664) DUF869 PF05911.6 ABX12341.1 - 0.00067 18.0 44.7 0.00077 17.8 21.9 2.1 1 1 1 2 2 2 1 Plant protein of unknown function (DUF869) Spc7 PF08317.6 ABX12341.1 - 0.0013 17.4 44.3 0.098 11.2 5.7 3.6 1 1 2 3 3 3 2 Spc7 kinetochore protein NPV_P10 PF05531.7 ABX12341.1 - 0.0046 17.1 34.0 0.24 11.6 0.4 6.9 2 1 4 6 6 5 3 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.16 ABX12341.1 - 0.033 13.7 43.5 2.7 7.4 4.1 4.6 1 1 4 5 5 5 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1192 PF06698.6 ABX12341.1 - 0.035 13.9 5.5 16 5.3 0.2 4.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) TSC22 PF01166.13 ABX12341.1 - 0.088 12.7 8.3 3 7.8 0.0 4.7 4 0 0 4 4 4 0 TSC-22/dip/bun family AAA_13 PF13166.1 ABX12341.1 - 0.14 10.5 45.9 0.0071 14.8 14.4 3.1 1 1 2 3 3 3 0 AAA domain Laminin_II PF06009.7 ABX12341.1 - 0.14 11.8 43.4 0.033 13.9 4.7 5.0 1 1 3 5 5 5 0 Laminin Domain II BLOC1_2 PF10046.4 ABX12341.1 - 0.52 10.4 41.5 0.34 11.0 0.1 6.1 1 1 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 ABX12341.1 - 0.86 9.5 32.7 9.5 6.1 0.5 6.4 1 1 5 6 6 6 0 Bacterial protein of unknown function (DUF948) AKNA PF12443.3 ABX12341.1 - 0.96 9.5 17.3 0.11 12.4 2.7 5.0 1 1 4 6 6 6 0 AT-hook-containing transcription factor DUF1706 PF08020.6 ABX12341.1 - 2.4 7.6 10.0 0.85 9.1 2.9 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1706) DUF3086 PF11285.3 ABX12341.1 - 3.2 6.5 20.9 0.018 13.8 4.6 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3086) Na_H_Exchanger PF00999.16 ABX12342.1 - 6.1e-59 199.4 54.8 7.7e-59 199.1 38.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family JmjN PF02375.12 ABX12344.1 - 0.0051 16.3 0.7 0.0099 15.3 0.5 1.5 1 0 0 1 1 1 1 jmjN domain ssDNA-exonuc_C PF10141.4 ABX12344.1 - 0.071 12.6 0.9 0.089 12.2 0.6 1.3 1 1 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain DUF3647 PF12363.3 ABX12344.1 - 0.095 12.8 1.5 1.9 8.6 0.3 2.1 2 0 0 2 2 2 0 Phage protein Ribosomal_L16 PF00252.13 ABX12345.1 - 3.8e-23 81.6 1.1 4.6e-23 81.4 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e tRNA_int_endo PF01974.12 ABX12346.1 - 3.4e-20 71.6 0.2 1.6e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 ABX12346.1 - 4.3e-13 48.5 3.6 7.2e-12 44.6 0.4 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain DUF4363 PF14276.1 ABX12347.1 - 0.14 11.8 1.3 0.41 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Response_reg PF00072.19 ABX12348.1 - 2.6e-21 75.7 0.6 3.1e-21 75.4 0.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Peripla_BP_4 PF13407.1 ABX12348.1 - 0.019 14.2 0.1 0.024 14.0 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain B12-binding PF02310.14 ABX12348.1 - 0.049 13.5 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain 2-Hacid_dh PF00389.25 ABX12348.1 - 0.056 12.9 1.3 5.5 6.4 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Sigma70_r1_1 PF03979.9 ABX12348.1 - 0.13 12.2 0.1 0.13 12.2 0.1 1.7 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 DUF1312 PF07009.6 ABX12350.1 - 0.2 11.4 0.9 1.7 8.4 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1312) TcdB_toxin_midN PF12256.3 ABX12351.1 - 0.042 13.3 0.6 0.34 10.3 0.1 2.1 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region DUF1034 PF06280.7 ABX12351.1 - 3.3 8.1 7.4 28 5.1 3.0 3.0 1 1 1 2 2 2 0 Fn3-like domain (DUF1034) DUF3290 PF11694.3 ABX12353.1 - 0.098 12.3 0.1 0.65 9.7 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3290) FixH PF05751.6 ABX12354.1 - 0.062 13.1 0.2 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 FixH DUF1737 PF08410.5 ABX12355.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) CHASE3 PF05227.8 ABX12356.1 - 2.6e-49 166.4 11.8 7.4e-29 100.1 0.1 2.9 3 1 0 3 3 3 2 CHASE3 domain HATPase_c PF02518.21 ABX12356.1 - 2.1e-20 72.4 0.0 9.3e-20 70.4 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ABX12356.1 - 3.5e-12 46.1 0.4 1.7e-11 43.9 0.3 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 ABX12356.1 - 4.8e-11 42.6 3.5 6.9e-11 42.1 0.0 2.8 3 0 0 3 3 3 1 HAMP domain HATPase_c_5 PF14501.1 ABX12356.1 - 3.6e-07 29.8 0.1 1.5e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 GHKL domain 4HB_MCP_1 PF12729.2 ABX12356.1 - 0.00024 20.4 0.1 0.00024 20.4 0.1 3.4 3 1 0 3 3 3 1 Four helix bundle sensory module for signal transduction Glyco_tran_WbsX PF14307.1 ABX12356.1 - 0.094 11.8 0.2 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase WbsX DUF4231 PF14015.1 ABX12357.1 - 0.039 13.9 0.3 0.039 13.9 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3040 PF11239.3 ABX12357.1 - 3.2 7.8 7.4 32 4.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) HEAT_2 PF13646.1 ABX12358.1 - 5e-13 49.1 0.1 1.6e-11 44.3 0.1 2.0 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 ABX12358.1 - 2.6e-06 27.0 0.6 0.2 11.8 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat Nnf1 PF03980.9 ABX12358.1 - 0.013 15.5 0.1 0.051 13.5 0.0 1.8 2 0 0 2 2 2 0 Nnf1 Cnd1 PF12717.2 ABX12358.1 - 0.079 12.7 0.1 0.15 11.8 0.1 1.5 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 EamA PF00892.15 ABX12359.1 - 7.2e-25 87.4 29.5 2.6e-16 59.8 2.2 2.5 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 ABX12359.1 - 1.3e-08 34.5 27.5 4.8e-07 29.5 3.1 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 ABX12359.1 - 1.8e-08 34.5 28.0 8.9e-07 29.1 1.5 3.2 2 2 1 3 3 3 2 Multidrug resistance efflux transporter DUF914 PF06027.7 ABX12359.1 - 4.3e-05 22.5 17.5 5.5e-05 22.1 12.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) Sugar_transport PF06800.7 ABX12359.1 - 0.00023 20.3 2.3 0.00023 20.3 1.6 2.2 1 1 1 2 2 2 2 Sugar transport protein UPF0546 PF10639.4 ABX12359.1 - 0.00099 18.9 2.0 0.00099 18.9 1.4 2.5 2 1 0 2 2 2 1 Uncharacterised protein family UPF0546 UAA PF08449.6 ABX12359.1 - 0.003 16.5 2.7 0.003 16.5 1.9 2.5 2 1 0 2 2 2 1 UAA transporter family HTH_45 PF14947.1 ABX12360.1 - 0.018 14.8 0.2 0.046 13.5 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DUF666 PF05006.7 ABX12360.1 - 0.037 14.0 0.1 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF666) TrmB PF01978.14 ABX12360.1 - 0.081 12.6 0.1 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Response_reg PF00072.19 ABX12361.1 - 7.2e-20 71.0 2.6 8.8e-20 70.7 1.8 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HAD PF12710.2 ABX12361.1 - 0.00075 19.7 0.0 0.00087 19.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ANF_receptor PF01094.23 ABX12361.1 - 0.011 14.5 0.7 0.011 14.4 0.5 1.0 1 0 0 1 1 1 0 Receptor family ligand binding region DUF2325 PF10087.4 ABX12361.1 - 0.027 14.2 0.1 0.07 12.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) ATP-synt_F PF01990.12 ABX12361.1 - 0.043 14.2 1.1 0.2 12.0 0.1 2.1 2 1 0 2 2 2 0 ATP synthase (F/14-kDa) subunit PPP5 PF08321.7 ABX12361.1 - 0.12 12.3 0.8 0.27 11.2 0.3 1.8 1 1 1 2 2 2 0 PPP5 TPR repeat region TPR_11 PF13414.1 ABX12364.1 - 1.8e-16 59.5 0.1 3.1e-08 33.1 0.0 2.4 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ABX12364.1 - 4.1e-13 48.3 0.5 0.00053 19.4 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 ABX12364.1 - 2.1e-12 47.1 0.1 9.7e-08 32.2 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ABX12364.1 - 4.4e-11 41.8 0.1 0.0084 15.9 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ABX12364.1 - 8.2e-09 35.3 0.0 0.075 13.7 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 ABX12364.1 - 1.4e-08 34.7 0.0 2.3e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 ABX12364.1 - 3e-07 29.7 0.1 0.056 13.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ABX12364.1 - 3.6e-06 26.7 0.0 0.0038 17.1 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ABX12364.1 - 4.3e-06 26.1 0.0 1.2 9.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ABX12364.1 - 6.1e-06 26.7 0.0 0.009 16.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ABX12364.1 - 0.00023 21.0 0.6 16 5.9 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ABX12364.1 - 0.0007 19.4 0.6 0.022 14.6 0.0 2.7 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 ABX12364.1 - 0.00089 19.0 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat NARP1 PF12569.3 ABX12364.1 - 0.0016 17.2 0.1 0.003 16.4 0.0 1.4 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 ABX12364.1 - 0.0081 15.2 0.0 0.044 12.8 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.5 ABX12364.1 - 0.0098 14.6 0.0 0.011 14.5 0.0 1.0 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 ABX12364.1 - 0.087 13.3 0.0 8.3 7.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_Tnp_Tc5 PF03221.11 ABX12365.1 - 0.0028 17.4 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PqqD PF05402.7 ABX12365.1 - 0.15 12.0 0.6 0.62 10.1 0.1 2.2 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) Beta_propel PF09826.4 ABX12367.1 - 1.9e-174 580.8 11.0 2.2e-174 580.6 7.6 1.0 1 0 0 1 1 1 1 Beta propeller domain HMG_box_2 PF09011.5 ABX12367.1 - 0.21 11.9 1.0 0.55 10.6 0.7 1.6 1 0 0 1 1 1 0 HMG-box domain LVIVD PF08309.6 ABX12367.1 - 1.1 8.2 7.6 5.5 6.0 0.1 4.1 4 0 0 4 4 4 0 LVIVD repeat HTH_20 PF12840.2 ABX12368.1 - 9.6e-10 38.1 0.0 1.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 ABX12368.1 - 3.8e-09 35.7 0.2 8.1e-09 34.7 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 ABX12368.1 - 1.2e-08 34.4 0.4 3.5e-08 32.9 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family TFIIE_alpha PF02002.12 ABX12368.1 - 1.1e-05 24.9 0.3 1.7e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TrmB PF01978.14 ABX12368.1 - 1.8e-05 24.3 0.1 3.2e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 ABX12368.1 - 3e-05 23.5 0.3 7.5e-05 22.3 0.2 1.7 1 0 0 1 1 1 1 HTH domain Sigma70_r4 PF04545.11 ABX12368.1 - 0.00085 18.5 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.2 ABX12368.1 - 0.0013 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.1 ABX12368.1 - 0.0016 18.3 0.7 0.0032 17.4 0.5 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain Sigma70_r4_2 PF08281.7 ABX12368.1 - 0.0041 16.5 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Rrf2 PF02082.15 ABX12368.1 - 0.012 15.7 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_27 PF13463.1 ABX12368.1 - 0.012 15.9 0.1 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF2250 PF10007.4 ABX12368.1 - 0.026 14.4 0.3 0.046 13.6 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) GerE PF00196.14 ABX12368.1 - 0.1 11.8 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_38 PF13936.1 ABX12368.1 - 0.12 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF385 PF04075.9 ABX12369.1 - 6.8e-07 29.3 0.0 8.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF385) DUF2255 PF10012.4 ABX12369.1 - 0.00026 20.9 0.0 0.00029 20.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2255) PRC PF05239.11 ABX12370.1 - 1.6e-08 34.3 0.6 0.00036 20.3 0.1 2.2 2 0 0 2 2 2 2 PRC-barrel domain MCE PF02470.15 ABX12370.1 - 0.1 12.6 0.0 0.56 10.2 0.0 1.9 1 1 1 2 2 2 0 mce related protein ABC_tran PF00005.22 ABX12371.1 - 9.9e-32 110.1 0.0 1.8e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ABX12371.1 - 6.7e-12 45.9 6.6 6e-09 36.2 0.2 2.7 2 1 0 3 3 3 2 AAA domain DUF4162 PF13732.1 ABX12371.1 - 3.7e-07 30.5 0.8 8.3e-07 29.4 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_15 PF13175.1 ABX12371.1 - 1.3e-05 24.4 6.2 0.00028 20.0 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 ABX12371.1 - 0.00058 19.3 0.3 0.0012 18.3 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 ABX12371.1 - 0.01 15.0 0.2 0.048 12.8 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ABX12371.1 - 0.011 16.1 5.3 0.033 14.5 3.5 2.2 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 ABX12371.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 ABX12371.1 - 0.11 12.6 0.0 0.34 11.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 ABX12371.1 - 0.14 12.2 0.5 1.4 9.0 0.2 2.4 2 1 0 2 2 2 0 AAA domain ABC2_membrane PF01061.19 ABX12372.1 - 1.2e-33 116.1 19.3 1.2e-33 116.1 13.4 1.9 1 1 1 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 ABX12372.1 - 4.6e-17 62.0 31.8 5.7e-17 61.7 22.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 ABX12372.1 - 5.1e-10 38.9 25.5 6.5e-10 38.5 17.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 ABX12372.1 - 6.3e-07 28.5 24.9 1.3e-06 27.4 17.3 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.1 ABX12372.1 - 8.6 5.5 26.3 54 2.9 18.2 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein NHL PF01436.16 ABX12373.1 - 2e-36 122.0 2.7 5.4e-06 26.1 0.0 7.4 7 0 0 7 7 7 5 NHL repeat SGL PF08450.7 ABX12373.1 - 3.3e-09 36.4 0.7 0.00075 18.9 0.1 4.3 2 2 2 4 4 4 2 SMP-30/Gluconolaconase/LRE-like region HemolysinCabind PF00353.14 ABX12373.1 - 5.1e-08 32.5 44.4 0.021 15.1 0.6 6.2 2 1 6 8 8 8 8 Hemolysin-type calcium-binding repeat (2 copies) SBBP PF06739.6 ABX12373.1 - 2e-07 30.6 16.2 0.0058 16.3 0.7 5.9 7 0 0 7 7 7 3 Beta-propeller repeat HYR PF02494.11 ABX12373.1 - 0.00025 21.0 0.2 0.00054 19.9 0.1 1.6 1 0 0 1 1 1 1 HYR domain Arylesterase PF01731.15 ABX12373.1 - 0.0032 17.3 0.6 1.4 8.9 0.0 3.5 4 0 0 4 4 4 1 Arylesterase LVIVD PF08309.6 ABX12373.1 - 0.0037 16.2 3.4 1.2 8.1 0.0 3.1 3 0 0 3 3 3 2 LVIVD repeat Ldl_recept_b PF00058.12 ABX12373.1 - 0.038 14.3 0.0 1.2e+02 3.1 0.0 4.7 4 1 0 4 4 4 0 Low-density lipoprotein receptor repeat class B SdiA-regulated PF06977.6 ABX12373.1 - 0.089 11.7 0.0 4.4 6.1 0.0 2.5 1 1 1 2 2 2 0 SdiA-regulated Big_3_4 PF13754.1 ABX12373.1 - 0.19 12.0 2.9 0.17 12.2 0.4 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Reg_prop PF07494.6 ABX12373.1 - 0.28 11.3 2.6 31 5.0 0.1 4.6 5 0 0 5 5 5 0 Two component regulator propeller Tcp10_C PF07202.8 ABX12374.1 - 0.003 17.1 2.6 0.16 11.4 0.1 3.2 3 0 0 3 3 3 2 T-complex protein 10 C-terminus PBP_like_2 PF12849.2 ABX12375.1 - 5.2e-52 177.0 2.2 7.2e-52 176.5 1.5 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.20 ABX12375.1 - 8.4e-16 58.5 1.6 1.2e-15 58.1 1.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.2 ABX12375.1 - 1.3e-06 27.4 0.0 4.2e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 PBP superfamily domain BPD_transp_1 PF00528.17 ABX12377.1 - 1e-17 64.2 16.8 1e-17 64.2 11.7 2.2 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.17 ABX12378.1 - 3.7e-18 65.6 20.0 5.1e-18 65.2 9.8 2.1 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.22 ABX12379.1 - 4.8e-30 104.6 0.0 7.6e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ABX12379.1 - 2.3e-15 57.3 0.0 2.2e-08 34.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 ABX12379.1 - 1.5e-10 40.6 0.2 3.9e-10 39.3 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 ABX12379.1 - 1.1e-06 28.0 3.2 0.014 14.4 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 ABX12379.1 - 1.5e-05 25.1 0.0 5.2e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 ABX12379.1 - 4.6e-05 22.6 0.0 8.9e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 ABX12379.1 - 5.7e-05 23.5 1.2 0.00018 21.9 0.9 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ABX12379.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 ABX12379.1 - 0.0012 18.6 0.3 0.031 13.9 0.2 2.2 1 1 0 1 1 1 1 Archaeal ATPase Rad17 PF03215.10 ABX12379.1 - 0.0012 17.6 0.0 0.0018 17.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 ABX12379.1 - 0.0034 17.4 0.2 0.0099 15.8 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 ABX12379.1 - 0.0064 15.9 0.2 0.14 11.5 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain AAA_18 PF13238.1 ABX12379.1 - 0.0066 16.7 0.0 0.017 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.15 ABX12379.1 - 0.014 14.1 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA PF00004.24 ABX12379.1 - 0.014 15.5 0.1 0.3 11.3 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ABX12379.1 - 0.015 16.1 0.1 0.031 15.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ABX12379.1 - 0.018 14.9 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ABX12379.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 ABX12379.1 - 0.032 13.9 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain PRK PF00485.13 ABX12379.1 - 0.035 13.6 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.4 ABX12379.1 - 0.042 13.3 0.2 0.14 11.6 0.0 2.0 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 ABX12379.1 - 0.053 13.4 0.2 0.16 11.8 0.2 2.2 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 ABX12379.1 - 0.053 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 ABX12379.1 - 0.06 12.5 0.2 0.48 9.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 ABX12379.1 - 0.062 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 ABX12379.1 - 0.071 12.6 0.1 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 ABX12379.1 - 0.094 12.1 0.1 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain PhoU PF01895.14 ABX12380.1 - 1.8e-19 69.9 6.5 2.3e-10 40.7 1.5 2.2 2 0 0 2 2 2 2 PhoU domain Sec66 PF09802.4 ABX12380.1 - 0.029 13.7 0.2 0.046 13.1 0.2 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 DUF897 PF05982.7 ABX12381.1 - 6.8e-91 304.4 23.1 8.3e-91 304.1 16.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF897) DUF3240 PF11582.3 ABX12382.1 - 9.5e-05 22.2 0.2 0.00034 20.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3240) P-II PF00543.17 ABX12382.1 - 0.0001 22.7 0.2 0.00014 22.2 0.1 1.2 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF190 PF02641.10 ABX12382.1 - 0.032 14.1 0.7 0.043 13.6 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 Rad1 PF02144.11 ABX12382.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 OsmC PF02566.14 ABX12382.1 - 0.12 12.5 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 OsmC-like protein HTH_5 PF01022.15 ABX12383.1 - 1.1e-15 57.0 0.1 2e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 ABX12383.1 - 4.9e-10 39.0 0.0 7.4e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 ABX12383.1 - 7.9e-08 31.5 0.2 2.9e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 ABX12383.1 - 6.9e-05 22.4 0.0 0.00037 20.1 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_34 PF13601.1 ABX12383.1 - 0.00024 21.0 0.0 0.0004 20.3 0.0 1.4 1 1 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.14 ABX12383.1 - 0.00033 20.3 0.0 0.00044 19.9 0.0 1.1 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 ABX12383.1 - 0.022 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 MarR family Penicillinase_R PF03965.11 ABX12383.1 - 0.039 14.0 0.1 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor TFIIE_alpha PF02002.12 ABX12383.1 - 0.049 13.1 0.3 0.065 12.7 0.2 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit TBPIP PF07106.8 ABX12383.1 - 0.064 12.8 0.5 0.073 12.6 0.3 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Arg_repressor PF01316.16 ABX12383.1 - 0.12 11.8 0.1 0.24 11.0 0.1 1.6 1 1 0 1 1 1 0 Arginine repressor, DNA binding domain LMWPc PF01451.16 ABX12384.1 - 1.9e-27 96.2 0.1 2.3e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase MIP PF00230.15 ABX12385.1 - 3.3e-39 134.6 17.7 3.7e-39 134.5 12.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF2105 PF09878.4 ABX12385.1 - 0.026 14.1 5.6 0.043 13.3 3.6 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2105) Aminotran_3 PF00202.16 ABX12386.1 - 5.7e-71 239.1 0.1 7.2e-71 238.7 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 ABX12386.1 - 1.2e-05 24.4 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II z-alpha PF02295.12 ABX12386.1 - 0.083 12.6 0.7 0.24 11.1 0.1 2.2 3 0 0 3 3 3 0 Adenosine deaminase z-alpha domain Porphobil_deam PF01379.15 ABX12387.1 - 4.8e-72 241.3 0.1 6.7e-72 240.8 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 ABX12387.1 - 1.3e-12 47.6 0.0 4.7e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain TP_methylase PF00590.15 ABX12388.1 - 1.6e-49 168.4 0.0 1.8e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DAGK_cat PF00781.19 ABX12388.1 - 0.04 13.3 0.2 0.19 11.1 0.0 2.2 2 1 1 3 3 3 0 Diacylglycerol kinase catalytic domain tRNA_int_endo PF01974.12 ABX12388.1 - 0.13 12.0 1.8 0.27 11.0 0.1 2.4 2 1 1 3 3 3 0 tRNA intron endonuclease, catalytic C-terminal domain HEM4 PF02602.10 ABX12389.1 - 1.1e-44 152.3 0.0 1.3e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Cys_rich_CPXG PF14255.1 ABX12390.1 - 0.0042 16.8 0.1 0.006 16.3 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich CPXCG DUF177 PF02620.12 ABX12390.1 - 0.0097 15.9 0.2 0.012 15.6 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1399 SoxD PF04267.7 ABX12390.1 - 0.012 15.3 0.5 0.015 15.1 0.3 1.2 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family FYDLN_acid PF09538.5 ABX12390.1 - 0.021 15.3 9.6 0.024 15.2 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-LITAF-like PF10601.4 ABX12390.1 - 0.06 13.2 0.1 0.095 12.5 0.1 1.2 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DUF1178 PF06676.6 ABX12390.1 - 0.39 10.8 6.4 0.42 10.7 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) BLVR PF06375.6 ABX12390.1 - 0.51 10.1 20.9 0.56 10.0 14.5 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SspB PF04386.8 ABX12390.1 - 0.59 9.7 6.3 0.56 9.8 4.4 1.1 1 0 0 1 1 1 0 Stringent starvation protein B RPOL_N PF14700.1 ABX12390.1 - 1.6 7.9 8.0 1.7 7.8 5.5 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal RNA_pol_Rbc25 PF08292.7 ABX12390.1 - 2.7 8.2 7.5 2.7 8.1 5.2 1.0 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Peptidase_S49_N PF08496.5 ABX12390.1 - 3 7.6 17.3 3 7.6 12.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rtf2 PF04641.7 ABX12390.1 - 5.9 6.0 19.6 6.4 5.8 13.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2992 PF11208.3 ABX12390.1 - 7 6.5 22.8 7 6.5 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Vfa1 PF08432.5 ABX12390.1 - 7.1 6.6 21.4 7.2 6.5 14.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.7 ABX12390.1 - 7.5 6.4 13.7 7.6 6.4 9.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Med19 PF10278.4 ABX12390.1 - 8.4 6.0 25.6 8.2 6.0 17.7 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF2956 PF11169.3 ABX12390.1 - 9 6.3 18.6 10 6.1 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) UPF0051 PF01458.12 ABX12391.1 - 8.5e-70 234.7 0.2 1.1e-69 234.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) UPF0051 PF01458.12 ABX12392.1 - 3.7e-68 229.4 2.6 5.1e-68 228.9 1.8 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF4116 PF13475.1 ABX12392.1 - 0.012 15.1 0.1 0.035 13.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Aminotran_5 PF00266.14 ABX12393.1 - 2e-150 500.6 0.2 2.3e-150 500.4 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 ABX12393.1 - 0.00045 19.4 0.0 0.00067 18.8 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase DUF4582 PF15189.1 ABX12393.1 - 0.003 16.8 1.2 0.68 9.1 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4582) HAUS5 PF14817.1 ABX12393.1 - 0.19 10.2 0.1 0.24 9.9 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 NifU_N PF01592.11 ABX12394.1 - 3.1e-29 101.4 0.1 3.6e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF1033 PF06279.6 ABX12395.1 - 0.063 13.0 0.2 0.15 11.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) Ribosomal_S27 PF01599.14 ABX12395.1 - 0.075 12.8 1.3 0.33 10.8 1.0 1.9 1 1 0 1 1 1 0 Ribosomal protein S27a PGK PF00162.14 ABX12396.1 - 1e-112 376.5 0.6 1.1e-112 376.3 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase CbiA PF01656.18 ABX12396.1 - 0.00043 19.7 0.2 0.08 12.3 0.0 2.3 1 1 1 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain DUF218 PF02698.12 ABX12396.1 - 0.0021 17.5 0.1 0.41 10.1 0.0 2.4 2 0 0 2 2 2 2 DUF218 domain PAP2 PF01569.16 ABX12397.1 - 3.8e-21 75.1 0.3 3.8e-21 75.1 0.2 1.9 2 1 1 3 3 3 2 PAP2 superfamily PAP2_3 PF14378.1 ABX12397.1 - 2.5e-05 23.9 2.3 2.5e-05 23.9 1.6 2.2 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 ABX12397.1 - 0.00014 22.0 0.2 0.00014 22.0 0.1 2.7 3 1 0 3 3 3 1 PAP2 superfamily C-terminal DUF2834 PF11196.3 ABX12397.1 - 0.52 10.5 3.5 1.5 8.9 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2834) Wzy_C PF04932.10 ABX12397.1 - 4.3 7.1 11.0 5.4 6.7 4.2 2.8 1 1 1 2 2 2 0 O-Antigen ligase Baculo_PEP_C PF04513.7 ABX12399.1 - 2.6 7.8 7.2 0.72 9.6 1.4 2.5 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 ABX12399.1 - 6.7 5.7 14.2 6.1 5.9 2.4 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 ABX12399.1 - 9.1 6.6 14.5 7.3 6.9 0.2 3.8 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ABC2_membrane_4 PF12730.2 ABX12400.1 - 0.52 9.4 5.3 2.7 7.0 0.8 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4064 PF13273.1 ABX12400.1 - 1.6 8.8 6.7 0.52 10.4 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) IncA PF04156.9 ABX12400.1 - 3.5 7.1 6.3 5.2 6.6 0.1 2.2 2 0 0 2 2 2 0 IncA protein tRNA_anti-codon PF01336.20 ABX12401.1 - 0.00088 19.0 0.2 0.0011 18.7 0.1 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SNARE_assoc PF09335.6 ABX12402.1 - 0.00046 20.3 5.4 0.001 19.2 3.7 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein HD PF01966.17 ABX12403.1 - 5.8e-16 58.6 0.3 8.5e-16 58.0 0.2 1.3 1 0 0 1 1 1 1 HD domain DUF1896 PF08989.5 ABX12404.1 - 0.036 13.9 0.4 0.051 13.4 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1896) JmjN PF02375.12 ABX12404.1 - 0.14 11.6 1.7 1.6 8.3 0.1 2.6 1 1 1 2 2 2 0 jmjN domain ALAD PF00490.16 ABX12405.1 - 7.3e-138 458.8 0.6 8.3e-138 458.6 0.4 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF2070 PF09843.4 ABX12405.1 - 0.0033 16.9 0.4 0.0074 15.7 0.1 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2070) GlutR_N PF05201.10 ABX12406.1 - 2.8e-42 143.8 0.3 2.8e-42 143.8 0.2 1.8 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.15 ABX12406.1 - 2.8e-23 82.5 0.0 7.7e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.15 ABX12406.1 - 9.4e-22 76.8 2.6 2.2e-21 75.6 1.8 1.7 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain 2-Hacid_dh_C PF02826.14 ABX12406.1 - 0.00053 19.1 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 ABX12406.1 - 0.0024 18.2 0.0 0.0073 16.7 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 ABX12406.1 - 0.017 15.0 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_7 PF13241.1 ABX12406.1 - 0.027 14.7 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding MutS_III PF05192.13 ABX12406.1 - 0.058 13.1 0.6 0.82 9.4 0.5 2.2 1 1 0 1 1 1 0 MutS domain III LVIVD PF08309.6 ABX12406.1 - 0.072 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 LVIVD repeat Arch_ATPase PF01637.13 ABX12406.1 - 7.6 6.1 12.0 7.5 6.1 6.4 2.3 2 1 0 2 2 2 0 Archaeal ATPase DUF1664 PF07889.7 ABX12406.1 - 8.1 6.2 14.3 9.9 5.9 0.9 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) NAD_binding_7 PF13241.1 ABX12407.1 - 1.1e-20 73.8 2.5 1.8e-20 73.1 0.3 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 ABX12407.1 - 1.3e-06 28.5 0.3 2.5e-06 27.6 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SKI PF01202.17 ABX12407.1 - 0.0022 17.8 1.7 0.0028 17.5 0.1 2.0 2 1 0 2 2 2 1 Shikimate kinase TrkA_N PF02254.13 ABX12407.1 - 0.003 17.5 0.2 0.005 16.8 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.14 ABX12407.1 - 0.0048 15.5 0.0 0.0078 14.8 0.0 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase THF_DHG_CYH_C PF02882.14 ABX12407.1 - 0.015 14.4 0.3 0.03 13.4 0.2 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HAD_2 PF13419.1 ABX12407.1 - 0.04 14.1 0.1 2.3 8.4 0.0 2.4 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase IlvN PF07991.7 ABX12407.1 - 0.13 11.5 0.9 0.21 10.9 0.6 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ATP-synt_F PF01990.12 ABX12407.1 - 0.29 11.5 7.4 0.55 10.6 0.1 3.0 3 1 0 3 3 3 0 ATP synthase (F/14-kDa) subunit BRICHOS PF04089.9 ABX12407.1 - 0.3 10.9 2.9 0.52 10.2 0.3 2.4 2 1 1 3 3 3 0 BRICHOS domain ARGLU PF15346.1 ABX12407.1 - 1 9.1 8.8 5.4 6.7 0.3 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Hpr_kinase_N PF02603.11 ABX12407.1 - 4.6 6.9 11.9 0.24 11.0 1.5 2.8 3 1 1 4 4 4 0 HPr Serine kinase N terminus HTH_AsnC-type PF13404.1 ABX12408.1 - 1.8e-05 24.1 0.0 0.00095 18.6 0.0 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.16 ABX12408.1 - 0.0063 16.2 0.0 11 5.8 0.0 3.9 3 1 0 3 3 3 2 AsnC family HTH_24 PF13412.1 ABX12408.1 - 0.01 15.1 0.3 0.082 12.3 0.2 2.3 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2316 PF10078.4 ABX12408.1 - 0.037 14.0 0.0 4.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) zf-B_box PF00643.19 ABX12409.1 - 0.024 14.5 3.1 0.039 13.8 2.2 1.3 1 0 0 1 1 1 0 B-box zinc finger Aldo_ket_red PF00248.16 ABX12410.1 - 7.9e-56 188.9 0.1 9e-56 188.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ECH_C PF13766.1 ABX12410.1 - 0.19 11.8 0.6 0.52 10.4 0.2 1.9 2 1 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Chlor_dismutase PF06778.7 ABX12411.1 - 1.5e-49 168.3 0.1 1.9e-49 168.0 0.1 1.0 1 0 0 1 1 1 1 Chlorite dismutase ABC_tran PF00005.22 ABX12412.1 - 1.8e-20 73.5 0.0 2.7e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 ABX12412.1 - 7.6e-11 41.6 0.4 5.7e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ABX12412.1 - 8.5e-11 42.3 0.1 3.7e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ABX12412.1 - 0.00014 21.3 0.4 0.00075 18.9 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ABX12412.1 - 0.00024 20.9 0.0 0.0004 20.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ABX12412.1 - 0.00048 19.6 0.1 0.0012 18.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ABX12412.1 - 0.0014 18.6 0.1 0.0038 17.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 ABX12412.1 - 0.0022 17.8 0.1 0.011 15.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.1 ABX12412.1 - 0.0043 15.5 0.4 0.11 10.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ABX12412.1 - 0.0059 16.8 0.3 0.22 11.7 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 ABX12412.1 - 0.007 16.7 0.8 0.024 14.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain MutS_V PF00488.16 ABX12412.1 - 0.0084 15.5 0.1 3.4 6.9 0.0 2.1 2 0 0 2 2 2 2 MutS domain V AAA_18 PF13238.1 ABX12412.1 - 0.0098 16.1 1.2 0.79 10.0 0.8 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ABX12412.1 - 0.015 16.1 0.3 0.037 14.8 0.2 2.1 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 ABX12412.1 - 0.02 14.6 0.5 0.14 11.8 0.1 2.0 1 1 1 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 ABX12412.1 - 0.025 14.6 0.1 0.086 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ABX12412.1 - 0.052 13.5 0.0 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 ABX12412.1 - 0.066 11.9 0.0 0.14 10.8 0.0 1.5 1 0 0 1 1 1 0 ArgK protein DUF258 PF03193.11 ABX12412.1 - 0.072 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 ABX12412.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 2 0 0 2 2 2 0 RNA helicase TFIIB PF00382.14 ABX12413.1 - 1.3e-23 82.5 0.7 2.8e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 ABX12413.1 - 6.9e-10 38.0 1.2 6.9e-10 38.0 0.8 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding RPA_interact_C PF14768.1 ABX12413.1 - 0.0094 16.3 0.9 0.92 9.9 0.1 2.7 2 0 0 2 2 2 1 Replication protein A interacting C-terminal RRN7 PF11781.3 ABX12413.1 - 0.032 13.7 2.0 0.04 13.4 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 ABX12413.1 - 0.066 13.0 1.6 0.39 10.5 0.5 2.2 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 ABX12413.1 - 0.11 12.2 0.8 0.4 10.5 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbons OrfB_Zn_ribbon PF07282.6 ABX12413.1 - 0.2 11.3 2.0 0.22 11.1 0.3 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF2318 PF10080.4 ABX12413.1 - 0.21 11.4 2.9 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) zf-ribbon_3 PF13248.1 ABX12413.1 - 1.6 8.0 6.2 0.096 11.9 0.7 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Spt4 PF06093.8 ABX12413.1 - 1.9 8.4 6.4 1.5 8.7 0.2 3.2 2 2 1 3 3 3 0 Spt4/RpoE2 zinc finger Gar1 PF04410.9 ABX12414.1 - 1.3e-06 27.9 0.1 1.5e-06 27.7 0.0 1.2 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region SRP19 PF01922.12 ABX12415.1 - 2.4e-16 60.0 0.0 2.9e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein Streptin-Immun PF11083.3 ABX12415.1 - 0.11 12.5 0.1 12 5.9 0.0 2.2 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Ribosomal_S8e PF01201.17 ABX12416.1 - 8.1e-22 77.7 7.9 8.8e-22 77.6 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L22 PF00237.14 ABX12416.1 - 0.061 13.2 0.1 0.088 12.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e TIMP PF00965.12 ABX12416.1 - 0.12 11.9 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase DUF387 PF04079.11 ABX12417.1 - 8.1e-36 122.7 0.6 9.7e-36 122.5 0.4 1.1 1 0 0 1 1 1 1 Putative transcriptional regulators (Ypuh-like) HTH_20 PF12840.2 ABX12417.1 - 0.036 13.8 0.0 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain PadR PF03551.9 ABX12417.1 - 0.083 12.6 0.3 0.49 10.1 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family FBP PF07299.6 ABX12417.1 - 0.087 12.1 1.1 0.73 9.1 0.0 2.1 1 1 0 2 2 2 0 Fibronectin-binding protein (FBP) ScpA_ScpB PF02616.9 ABX12418.1 - 4.6e-14 52.5 1.9 4.4e-06 26.4 0.0 2.1 1 1 1 2 2 2 2 ScpA/B protein ADH_N PF08240.7 ABX12419.1 - 4e-35 119.8 0.3 6.6e-35 119.1 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ABX12419.1 - 8.4e-30 102.9 0.2 1.5e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ABX12419.1 - 3e-10 41.0 0.0 4.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 ABX12419.1 - 0.0014 18.5 0.6 0.0027 17.6 0.4 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 ABX12419.1 - 0.062 13.2 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 ABX12419.1 - 0.07 12.9 0.2 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_16 PF10294.4 ABX12419.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase 3HCDH_N PF02737.13 ABX12419.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain VitK2_biosynth PF02621.9 ABX12420.1 - 4.8e-62 209.4 0.0 5.5e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis CxxCxxCC PF03692.10 ABX12421.1 - 7.7e-10 39.1 1.7 1.8e-09 37.9 1.1 1.7 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain eIF-1a PF01176.14 ABX12422.1 - 1.9e-20 72.0 1.0 2.5e-20 71.6 0.7 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CSD PF00313.17 ABX12423.1 - 7.7e-21 73.6 3.5 9.7e-21 73.3 2.5 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 ABX12423.1 - 1.5e-06 27.6 1.2 1.6e-06 27.5 0.8 1.1 1 0 0 1 1 1 1 Ribonuclease B OB domain Antitoxin-MazE PF04014.13 ABX12423.1 - 0.2 11.4 1.0 0.49 10.1 0.7 1.8 1 1 0 1 1 1 0 Antidote-toxin recognition MazE eIF-5a PF01287.15 ABX12425.1 - 2.4e-14 53.0 3.8 3.1e-14 52.6 2.6 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 ABX12425.1 - 0.0036 17.1 0.1 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 ABX12425.1 - 0.065 12.9 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 KOW motif EFP PF01132.15 ABX12425.1 - 0.093 12.4 0.8 0.27 10.9 0.1 1.9 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain DUF2866 PF11065.3 ABX12425.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) ATP_bind_4 PF01902.12 ABX12426.1 - 5.6e-61 205.6 0.0 6.3e-61 205.5 0.0 1.0 1 0 0 1 1 1 1 ATP-binding region Asn_synthase PF00733.16 ABX12426.1 - 1.4e-06 28.0 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 ABX12426.1 - 0.00016 21.0 0.0 0.00061 19.1 0.0 1.9 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Toxin-deaminase PF14424.1 ABX12426.1 - 0.011 15.7 0.1 0.031 14.2 0.0 1.8 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases tRNA_Me_trans PF03054.11 ABX12426.1 - 0.016 13.8 0.0 0.042 12.3 0.0 1.6 2 0 0 2 2 2 0 tRNA methyl transferase ThiI PF02568.9 ABX12426.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) SRP54 PF00448.17 ABX12427.1 - 8.7e-70 234.1 0.3 1.7e-69 233.1 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 ABX12427.1 - 3.2e-29 101.2 3.7 3.2e-29 101.2 2.6 3.0 4 0 0 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.14 ABX12427.1 - 4.8e-15 55.4 1.4 4.8e-15 55.4 0.9 2.2 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 ABX12427.1 - 5.4e-09 35.7 0.8 1.8e-08 34.0 0.6 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 ABX12427.1 - 1.5e-05 25.8 0.9 0.00014 22.6 0.6 2.4 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 ABX12427.1 - 2.5e-05 23.8 0.9 0.053 12.9 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 ABX12427.1 - 4.6e-05 22.3 0.5 0.00046 19.0 0.3 2.4 1 1 0 1 1 1 1 ArgK protein cobW PF02492.14 ABX12427.1 - 4.8e-05 22.8 1.1 0.00019 20.9 0.8 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 ABX12427.1 - 6.4e-05 22.6 0.4 0.00019 21.1 0.3 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.1 ABX12427.1 - 0.00015 21.7 0.3 0.026 14.4 0.0 2.7 2 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 ABX12427.1 - 0.00021 21.3 0.0 0.00082 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 ABX12427.1 - 0.0003 21.1 4.9 0.00032 20.9 0.2 3.0 3 2 0 3 3 2 1 AAA domain AAA_22 PF13401.1 ABX12427.1 - 0.00037 20.6 0.1 0.0019 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 ABX12427.1 - 0.00037 19.7 0.3 0.00087 18.5 0.0 1.7 2 0 0 2 2 1 1 Chromatin associated protein KTI12 AAA PF00004.24 ABX12427.1 - 0.00072 19.7 0.0 0.0037 17.4 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.13 ABX12427.1 - 0.00074 18.6 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase APS_kinase PF01583.15 ABX12427.1 - 0.00099 18.7 0.8 0.0025 17.4 0.0 2.0 3 0 0 3 3 1 1 Adenylylsulphate kinase AAA_10 PF12846.2 ABX12427.1 - 0.003 17.0 0.3 0.0076 15.7 0.1 1.7 1 1 1 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 ABX12427.1 - 0.0033 16.5 0.0 0.0056 15.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 ABX12427.1 - 0.0045 16.8 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 ABX12427.1 - 0.0055 16.0 0.4 0.016 14.6 0.3 1.8 1 0 0 1 1 1 1 Thymidylate kinase NTPase_1 PF03266.10 ABX12427.1 - 0.0084 15.8 0.8 0.021 14.5 0.3 2.0 2 1 0 2 2 1 1 NTPase AAA_5 PF07728.9 ABX12427.1 - 0.01 15.5 0.1 0.034 13.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.5 ABX12427.1 - 0.012 14.8 0.5 0.42 9.7 0.1 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit G-alpha PF00503.15 ABX12427.1 - 0.015 14.0 0.1 0.12 11.0 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_30 PF13604.1 ABX12427.1 - 0.016 14.7 0.0 0.04 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ABX12427.1 - 0.019 15.2 0.8 0.056 13.7 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Arf PF00025.16 ABX12427.1 - 0.024 13.8 0.0 0.074 12.2 0.0 1.8 1 0 0 1 1 1 0 ADP-ribosylation factor family LpxK PF02606.9 ABX12427.1 - 0.026 13.5 0.2 0.044 12.7 0.1 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase MipZ PF09140.6 ABX12427.1 - 0.026 13.5 0.6 0.82 8.6 0.4 2.3 1 1 0 1 1 1 0 ATPase MipZ ATP_bind_1 PF03029.12 ABX12427.1 - 0.034 13.6 0.2 0.079 12.4 0.1 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 ABX12427.1 - 0.046 13.6 0.2 0.083 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ABX12427.1 - 0.054 12.8 1.3 0.33 10.3 0.9 2.3 1 1 0 1 1 1 0 AAA domain LytR_C PF13399.1 ABX12427.1 - 0.099 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Cytidylate_kin2 PF13189.1 ABX12427.1 - 0.13 12.1 3.4 6.8 6.5 0.1 3.6 4 1 0 4 4 3 0 Cytidylate kinase-like family DUF3291 PF11695.3 ABX12427.1 - 0.16 11.4 0.1 0.81 9.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3291) Miro PF08477.8 ABX12427.1 - 0.18 12.2 1.0 2.1 8.8 0.7 2.4 1 1 0 1 1 1 0 Miro-like protein SpoVIF PF14069.1 ABX12427.1 - 0.32 10.7 3.3 0.23 11.2 0.4 2.2 2 0 0 2 2 1 0 Stage VI sporulation protein F AAA_23 PF13476.1 ABX12427.1 - 1.5 9.0 6.3 0.32 11.2 1.6 2.1 2 1 0 2 2 1 0 AAA domain THUMP PF02926.12 ABX12428.1 - 7.3e-07 29.1 0.0 1.9e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 THUMP domain PhoU_div PF01865.11 ABX12429.1 - 0.004 16.3 0.5 0.077 12.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF47 Ribosomal_S27 PF01599.14 ABX12430.1 - 8e-18 64.0 5.1 9.3e-18 63.7 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27a GCC2_GCC3 PF07699.8 ABX12430.1 - 7.8e-05 22.1 1.6 0.0001 21.8 1.1 1.2 1 0 0 1 1 1 1 GCC2 and GCC3 Ribosomal_L37e PF01907.14 ABX12430.1 - 0.00045 19.9 2.8 0.00059 19.5 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L37e NCD3G PF07562.9 ABX12430.1 - 0.0096 15.6 1.4 0.013 15.2 1.0 1.2 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR DUF1451 PF07295.6 ABX12430.1 - 0.0098 15.6 0.7 0.0099 15.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1451) DZR PF12773.2 ABX12430.1 - 0.013 15.2 0.7 0.02 14.6 0.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 ABX12430.1 - 0.015 14.7 1.7 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 ABX12430.1 - 0.018 14.6 2.0 0.023 14.3 1.4 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 ABX12430.1 - 0.041 13.3 3.4 0.08 12.4 2.3 1.5 1 1 0 1 1 1 0 A2L zinc ribbon domain GFA PF04828.9 ABX12430.1 - 0.048 13.6 2.5 0.14 12.1 0.1 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme SprT-like PF10263.4 ABX12430.1 - 0.05 13.2 0.7 0.049 13.2 0.5 1.0 1 0 0 1 1 1 0 SprT-like family zf-ribbon_3 PF13248.1 ABX12430.1 - 0.055 12.6 4.3 0.15 11.3 3.0 1.7 1 1 0 1 1 1 0 zinc-ribbon domain HypA PF01155.14 ABX12430.1 - 0.059 13.0 0.7 0.063 12.9 0.5 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-CCHC_5 PF14787.1 ABX12430.1 - 0.11 12.0 0.8 0.11 12.0 0.5 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-NADH-PPase PF09297.6 ABX12430.1 - 0.15 11.5 3.1 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-Mss51 PF13824.1 ABX12430.1 - 0.19 11.5 2.1 0.5 10.2 0.1 2.0 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Nudix_N_2 PF14803.1 ABX12430.1 - 0.21 11.3 6.6 5.3 6.8 0.6 2.2 1 1 1 2 2 2 0 Nudix N-terminal DUF2318 PF10080.4 ABX12430.1 - 0.21 11.3 1.8 0.22 11.2 1.2 1.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-C2H2_3 PF13878.1 ABX12430.1 - 0.41 10.2 4.4 2.5 7.7 0.2 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO MafB19-deam PF14437.1 ABX12430.1 - 1.5 8.4 4.9 11 5.6 1.2 2.6 1 1 2 3 3 3 0 MafB19-like deaminase Ribosomal_S24e PF01282.14 ABX12431.1 - 0.0022 17.7 0.1 0.0038 16.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e DUF309 PF03745.9 ABX12432.1 - 4.1e-17 61.3 0.1 6.1e-17 60.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF309) Glutaredoxin PF00462.19 ABX12432.1 - 0.1 12.5 0.3 2.6 8.1 0.0 2.6 2 1 1 3 3 3 0 Glutaredoxin PhosphMutase PF10143.4 ABX12433.1 - 4.1e-48 163.2 0.0 6.9e-48 162.5 0.0 1.4 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.13 ABX12433.1 - 2.1e-30 105.9 1.4 3.1e-30 105.3 1.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 ABX12433.1 - 0.0023 17.3 0.1 0.0047 16.3 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase GalP_UDP_transf PF01087.17 ABX12434.1 - 9.7e-10 38.7 0.0 3.4e-09 37.0 0.0 1.9 2 1 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.18 ABX12434.1 - 8.8e-05 22.9 0.0 0.00035 21.0 0.0 1.9 2 0 0 2 2 2 1 HIT domain GalP_UDP_tr_C PF02744.12 ABX12434.1 - 0.0031 17.0 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF2189 PF09955.4 ABX12435.1 - 0.00021 21.2 0.7 0.00036 20.4 0.3 1.5 1 1 0 1 1 1 1 Predicted integral membrane protein (DUF2189) DUF4064 PF13273.1 ABX12435.1 - 0.22 11.6 2.9 0.54 10.3 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Acetyltransf_1 PF00583.19 ABX12436.1 - 1.4e-17 63.4 0.0 1.9e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ABX12436.1 - 1.4e-15 57.1 0.1 2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ABX12436.1 - 1.7e-08 34.5 0.0 2.1e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ABX12436.1 - 7.5e-07 29.0 0.0 8.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ABX12436.1 - 0.00075 19.4 0.1 0.001 19.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ABX12436.1 - 0.0021 17.9 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 ABX12436.1 - 0.056 13.3 0.0 0.23 11.3 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NTP_transferase PF00483.18 ABX12437.1 - 2e-41 141.9 0.1 2.3e-41 141.7 0.1 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 ABX12437.1 - 2.5e-09 37.4 0.0 3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Mqo PF06039.10 ABX12437.1 - 0.0072 14.5 0.0 0.011 13.9 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) IspD PF01128.14 ABX12437.1 - 0.023 14.2 0.0 0.059 12.8 0.0 1.6 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Phos_pyr_kin PF08543.7 ABX12438.1 - 2.2e-74 249.7 4.5 5.4e-74 248.4 2.2 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Aldolase_2 PF10120.4 ABX12438.1 - 1.4e-55 187.2 0.2 4e-55 185.8 0.0 1.8 2 0 0 2 2 2 1 Putative aldolase PfkB PF00294.19 ABX12438.1 - 2.7e-12 46.4 0.0 4.3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 ABX12438.1 - 0.0003 20.1 0.6 0.00077 18.8 0.3 1.8 1 1 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 ABX12438.1 - 0.0013 17.9 0.6 0.0021 17.3 0.4 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family ThiC PF01964.13 ABX12439.1 - 2.8e-176 586.1 1.2 3.3e-176 585.9 0.9 1.0 1 0 0 1 1 1 1 ThiC family NUDIX PF00293.23 ABX12440.1 - 5.9e-12 45.3 0.0 6.5e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 ABX12440.1 - 0.00084 18.7 0.1 0.0019 17.6 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain PDH PF02153.12 ABX12441.1 - 1.1e-23 83.4 0.2 1.4e-23 83.1 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 ABX12441.1 - 1.3e-07 31.5 0.2 3.9e-07 30.0 0.0 1.8 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 ABX12441.1 - 8.8e-06 25.4 0.6 8.9e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 ABX12441.1 - 3e-05 23.2 0.0 5.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 ABX12441.1 - 0.00017 21.3 1.6 0.093 12.4 0.2 3.0 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 ABX12441.1 - 0.00027 21.2 0.4 0.0019 18.5 0.0 2.7 2 2 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 ABX12441.1 - 0.0003 20.1 0.1 0.0012 18.2 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_10 PF13460.1 ABX12441.1 - 0.00071 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding ThiF PF00899.16 ABX12441.1 - 0.0019 18.0 0.7 3.4 7.4 0.0 3.3 2 1 1 3 3 3 1 ThiF family Ldh_1_N PF00056.18 ABX12441.1 - 0.029 14.1 2.1 3 7.6 0.1 3.4 2 2 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.8 ABX12441.1 - 0.03 13.5 0.5 0.22 10.7 0.1 2.4 2 0 0 2 2 2 0 NmrA-like family CoA_binding_2 PF13380.1 ABX12441.1 - 0.031 14.4 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain Ada3 PF10198.4 ABX12441.1 - 0.044 13.5 1.1 0.073 12.8 0.2 1.7 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 Phage-tail_1 PF09097.5 ABX12441.1 - 0.08 12.5 0.3 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 Semialdhyde_dh PF01118.19 ABX12441.1 - 0.094 13.0 0.0 0.69 10.2 0.0 2.3 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 ABX12441.1 - 0.16 11.6 0.1 0.33 10.6 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Aminotran_1_2 PF00155.16 ABX12442.1 - 3.9e-61 207.0 0.1 5.1e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CM_2 PF01817.16 ABX12442.1 - 6.2e-13 48.6 1.4 4.7e-12 45.8 0.4 2.6 2 0 0 2 2 2 1 Chorismate mutase type II Aminotran_5 PF00266.14 ABX12442.1 - 8.3e-08 31.3 0.0 1.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 ABX12442.1 - 2.2e-06 26.1 0.0 3.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 ABX12442.1 - 0.00012 21.3 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 ABX12442.1 - 0.00013 21.1 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 ABX12442.1 - 0.00017 20.4 2.4 0.00058 18.6 0.3 2.5 3 0 0 3 3 3 1 Allinase DUF1396 PF07161.8 ABX12442.1 - 0.0019 17.8 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1396) Chorismate_synt PF01264.16 ABX12443.1 - 9e-142 471.6 1.0 1e-141 471.4 0.7 1.0 1 0 0 1 1 1 1 Chorismate synthase EAF PF09816.4 ABX12443.1 - 0.098 12.6 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription elongation factor EPSP_synthase PF00275.15 ABX12444.1 - 1.1e-96 323.8 0.0 1.3e-96 323.6 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) GHMP_kinases_N PF00288.21 ABX12445.1 - 1.3e-10 41.1 0.8 3e-10 40.0 0.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ABX12445.1 - 3.9e-05 23.7 0.1 0.0001 22.4 0.0 1.8 1 1 0 1 1 1 1 GHMP kinases C terminal Shikimate_dh_N PF08501.6 ABX12446.1 - 7.5e-29 99.6 0.0 2.3e-28 98.0 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 ABX12446.1 - 3.6e-17 62.7 0.8 5.2e-17 62.2 0.6 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 ABX12446.1 - 7.1e-06 25.2 0.2 9.3e-06 24.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 ABX12446.1 - 0.0044 17.4 1.0 0.0085 16.4 0.7 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 ABX12446.1 - 0.0075 16.5 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding CBAH PF02275.13 ABX12446.1 - 0.02 14.3 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family GARS_N PF02844.10 ABX12446.1 - 0.072 13.5 0.4 0.19 12.2 0.3 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain DUF2338 PF10100.4 ABX12446.1 - 0.11 10.8 0.1 0.14 10.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) DHquinase_I PF01487.10 ABX12447.1 - 3e-56 190.5 0.0 3.4e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Type I 3-dehydroquinase DHQS PF01959.11 ABX12448.1 - 2.4e-115 385.0 0.5 2.6e-115 384.9 0.4 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase (EC 4.6.1.3) DeoC PF01791.4 ABX12449.1 - 6.4e-47 159.8 0.0 7.5e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase DUF561 PF04481.7 ABX12449.1 - 0.12 11.2 0.1 0.23 10.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Radical_SAM PF04055.16 ABX12450.1 - 7e-18 65.3 0.0 1e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF2630 PF10944.3 ABX12450.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) UbiD PF01977.11 ABX12451.1 - 3.6e-155 516.4 0.1 4.4e-155 516.1 0.1 1.1 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF501 PF04417.7 ABX12451.1 - 0.33 10.7 1.6 3.8 7.3 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF501) ANF_receptor PF01094.23 ABX12452.1 - 4.1e-22 78.4 0.3 5.3e-22 78.0 0.2 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.1 ABX12452.1 - 1.3e-19 70.8 0.0 1.7e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein HATPase_c PF02518.21 ABX12452.1 - 7.7e-14 51.3 0.1 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Trypan_PARP PF05887.6 ABX12452.1 - 4.9e-05 23.1 172.4 0.19 11.5 47.6 3.8 2 1 1 3 3 3 1 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 ABX12452.1 - 0.00016 21.0 12.5 0.00016 21.0 8.7 6.2 1 1 5 6 6 6 1 Potato leaf roll virus readthrough protein HATPase_c_3 PF13589.1 ABX12452.1 - 0.0011 18.6 0.2 0.0026 17.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peripla_BP_5 PF13433.1 ABX12452.1 - 0.0074 15.0 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HATPase_c_2 PF13581.1 ABX12452.1 - 0.14 11.9 0.0 0.76 9.5 0.0 2.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Striatin PF08232.7 ABX12454.1 - 0.0052 17.1 2.3 0.0079 16.5 1.6 1.3 1 0 0 1 1 1 1 Striatin family M PF02370.11 ABX12454.1 - 0.54 10.7 3.8 2.4 8.7 2.7 2.2 1 0 0 1 1 1 0 M protein repeat DUF3373 PF11853.3 ABX12454.1 - 6 5.2 5.8 6.3 5.2 4.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) DUF3275 PF11679.3 ABX12454.1 - 6.1 6.4 10.0 11 5.5 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) PLC-beta_C PF08703.5 ABX12455.1 - 0.02 14.6 2.8 0.02 14.6 1.9 2.0 2 0 0 2 2 2 0 PLC-beta C terminal M PF02370.11 ABX12455.1 - 0.025 14.8 2.2 0.025 14.8 1.5 3.3 3 1 0 3 3 3 0 M protein repeat Striatin PF08232.7 ABX12455.1 - 0.11 12.8 9.0 0.12 12.7 1.9 2.3 2 0 0 2 2 2 0 Striatin family DivIC PF04977.10 ABX12455.1 - 0.16 11.4 0.1 0.16 11.4 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator SF-assemblin PF06705.6 ABX12455.1 - 0.54 9.3 4.7 0.36 9.9 0.7 1.9 2 0 0 2 2 2 0 SF-assemblin/beta giardin ERM PF00769.14 ABX12455.1 - 3.5 7.0 19.7 0.13 11.7 5.0 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family bZIP_1 PF00170.16 ABX12455.1 - 3.9 7.5 11.2 0.62 10.0 0.8 2.6 2 1 1 3 3 3 0 bZIP transcription factor Phage_GP20 PF06810.6 ABX12455.1 - 5.2 6.4 11.7 2.9 7.3 0.9 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 OmpH PF03938.9 ABX12455.1 - 6.2 6.7 12.5 1.7 8.5 2.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 ABX12455.1 - 8.8 5.1 10.8 4.6 6.1 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AhpC-TSA PF00578.16 ABX12456.1 - 9.2e-43 144.8 0.2 1.1e-42 144.6 0.2 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ABX12456.1 - 1e-28 99.7 0.1 1.2e-28 99.4 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 ABX12456.1 - 2.6e-08 33.7 0.0 4.2e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.7 ABX12456.1 - 2.4e-07 30.4 0.0 2.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Thioredoxin_8 PF13905.1 ABX12456.1 - 7.1e-05 22.8 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like SCO1-SenC PF02630.9 ABX12456.1 - 0.00011 21.8 1.3 0.00035 20.2 0.9 1.7 1 1 0 1 1 1 1 SCO1/SenC GSHPx PF00255.14 ABX12456.1 - 0.051 12.9 0.1 0.11 11.8 0.0 1.7 2 1 0 2 2 2 0 Glutathione peroxidase zf-C2H2_3 PF13878.1 ABX12456.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO MIP PF00230.15 ABX12457.1 - 6.5e-50 169.7 19.2 7.7e-50 169.4 13.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4233 PF14017.1 ABX12457.1 - 0.028 14.3 3.4 0.028 14.3 2.3 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF4233) Rcd1 PF04078.8 ABX12458.1 - 0.0025 16.7 0.8 0.0029 16.4 0.5 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like MMS19_C PF12460.3 ABX12458.1 - 0.0082 14.9 4.8 0.0094 14.7 3.3 1.0 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.3 ABX12458.1 - 0.011 15.7 1.1 0.013 15.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) DUF1247 PF06851.6 ABX12458.1 - 0.013 15.1 4.2 0.016 14.8 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1247) DUF445 PF04286.7 ABX12458.1 - 0.023 14.2 5.4 0.031 13.8 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1886 PF09171.5 ABX12458.1 - 0.037 13.0 1.5 0.093 11.7 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1886) GlutR_dimer PF00745.15 ABX12458.1 - 0.058 13.3 2.8 0.45 10.4 1.6 2.2 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain MAS20 PF02064.10 ABX12458.1 - 0.081 12.8 0.1 0.081 12.8 0.1 1.9 1 1 0 2 2 2 0 MAS20 protein import receptor DUF1840 PF08895.6 ABX12458.1 - 0.16 12.0 2.0 0.29 11.1 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) DUF489 PF04356.7 ABX12458.1 - 0.23 11.0 4.7 0.27 10.7 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF1241 PF06840.6 ABX12458.1 - 0.32 10.2 5.3 0.43 9.8 3.6 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1241) Vps39_1 PF10366.4 ABX12458.1 - 0.69 9.9 4.4 1.3 9.1 3.0 1.4 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 1 DUF4355 PF14265.1 ABX12458.1 - 1.1 9.2 9.5 0.74 9.7 5.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4355) Enkurin PF13864.1 ABX12458.1 - 2.6 8.3 9.2 1.6e+02 2.5 6.4 2.3 1 1 0 1 1 1 0 Calmodulin-binding DUF4363 PF14276.1 ABX12458.1 - 4.7 6.9 11.2 1.7 8.3 1.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) Methyltransf_26 PF13659.1 ABX12459.1 - 0.052 13.5 0.0 0.2 11.6 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 ABX12459.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 ABX12459.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 4HBT PF03061.17 ABX12460.1 - 0.00014 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Methyltransf_31 PF13847.1 ABX12461.1 - 8.3e-15 54.6 0.0 1.1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ABX12461.1 - 4.6e-11 42.9 0.0 7.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX12461.1 - 6.7e-09 36.3 0.0 1e-08 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ABX12461.1 - 2.5e-08 34.2 0.0 4.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ABX12461.1 - 3e-08 34.0 0.0 5.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ABX12461.1 - 5.6e-07 29.3 0.0 8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ABX12461.1 - 2.3e-06 26.9 0.1 3e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 ABX12461.1 - 6.1e-05 22.2 0.1 9.1e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.1 ABX12461.1 - 9.8e-05 22.1 0.0 0.00019 21.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ABX12461.1 - 0.00019 20.8 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 ABX12461.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 ABX12461.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Rsm22 PF09243.5 ABX12461.1 - 0.033 13.2 0.0 0.043 12.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 PCMT PF01135.14 ABX12461.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CBS PF00571.23 ABX12464.1 - 1.3e-25 88.9 0.3 8.9e-13 47.8 0.2 2.1 2 0 0 2 2 2 2 CBS domain DUF1705 PF08019.7 ABX12465.1 - 0.019 14.4 1.5 0.12 11.9 0.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF1705) BioY PF02632.9 ABX12465.1 - 0.29 10.7 4.1 0.53 9.9 2.9 1.4 1 1 0 1 1 1 0 BioY family Yip1 PF04893.12 ABX12465.1 - 2.9 7.3 9.3 7.2 6.0 6.4 1.7 1 1 0 1 1 1 0 Yip1 domain Adenine_glyco PF03352.8 ABX12466.1 - 4.6e-81 270.6 0.2 5.2e-81 270.4 0.2 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase Pro_CA PF00484.14 ABX12467.1 - 0.003 17.5 0.9 0.014 15.3 0.5 2.0 1 1 0 1 1 1 1 Carbonic anhydrase Vesiculo_matrix PF06326.7 ABX12467.1 - 0.061 12.7 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Vesiculovirus matrix protein MFS_1 PF07690.11 ABX12468.1 - 0.0084 14.8 45.5 0.25 10.0 12.1 3.5 2 2 0 2 2 2 2 Major Facilitator Superfamily Ferritin PF00210.19 ABX12469.1 - 2.7e-38 130.9 1.6 3.2e-38 130.6 1.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 ABX12469.1 - 0.00084 19.6 1.0 0.0012 19.1 0.7 1.2 1 0 0 1 1 1 1 Rubrerythrin DUF1477 PF07346.6 ABX12469.1 - 0.07 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) ATP-grasp_5 PF13549.1 ABX12469.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Ribosomal_L17 PF01196.14 ABX12469.1 - 0.11 13.0 0.2 0.15 12.6 0.1 1.4 1 1 0 1 1 1 0 Ribosomal protein L17 DUF1284 PF06935.6 ABX12470.1 - 0.12 12.5 3.4 0.16 12.1 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) GCC2_GCC3 PF07699.8 ABX12470.1 - 0.81 9.3 6.7 1.3 8.6 4.7 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 Prok-RING_1 PF14446.1 ABX12470.1 - 1.1 9.0 10.0 2.7 7.8 6.9 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DUF3990 PF13151.1 ABX12471.1 - 0.0055 16.1 0.0 0.0082 15.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3990) DegQ PF08181.6 ABX12471.1 - 4.6 7.0 5.8 12 5.6 0.2 2.8 2 1 0 3 3 3 0 DegQ (SacQ) family Pyridox_oxidase PF01243.15 ABX12472.1 - 5.8e-15 55.0 0.0 7.2e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.7 ABX12472.1 - 0.025 14.1 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WEMBL PF05701.6 ABX12473.1 - 3.4e-06 25.8 49.2 0.0038 15.7 3.1 2.5 2 1 0 2 2 2 2 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 ABX12473.1 - 2.9e-05 23.8 47.0 0.012 15.3 1.7 3.8 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein WXG100 PF06013.7 ABX12473.1 - 0.059 13.3 14.6 0.75 9.8 0.2 4.2 3 2 1 4 4 4 0 Proteins of 100 residues with WXG IncA PF04156.9 ABX12473.1 - 0.089 12.3 52.1 0.089 12.3 9.5 3.1 1 1 2 3 3 3 0 IncA protein FliJ PF02050.11 ABX12473.1 - 0.22 11.5 36.9 0.2 11.7 1.9 3.6 2 1 2 4 4 4 0 Flagellar FliJ protein MscS_porin PF12795.2 ABX12473.1 - 0.3 10.3 34.3 0.077 12.3 11.6 3.0 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain EzrA PF06160.7 ABX12473.1 - 0.83 7.7 42.4 0.32 9.1 9.4 3.0 1 1 1 3 3 3 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.7 ABX12473.1 - 2.1 8.6 14.6 4.5 7.5 1.4 3.8 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF745 PF05335.8 ABX12473.1 - 2.1 7.7 30.4 6.9 6.1 8.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF745) RmuC PF02646.11 ABX12473.1 - 2.8 6.6 27.2 0.52 9.1 2.9 3.0 2 1 0 3 3 3 0 RmuC family DUF4201 PF13870.1 ABX12473.1 - 3.4 7.0 44.4 1.3 8.4 3.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) DUF3135 PF11333.3 ABX12473.1 - 4 7.6 8.2 0.2 11.8 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) Reo_sigmaC PF04582.7 ABX12473.1 - 4.1 6.4 12.6 4.2 6.4 0.8 2.8 1 1 1 3 3 3 0 Reovirus sigma C capsid protein COG2 PF06148.6 ABX12473.1 - 4.3 7.2 28.1 5 6.9 5.2 3.4 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.3 ABX12473.1 - 4.6 7.1 44.9 1.9 8.3 10.1 3.7 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 ABX12473.1 - 4.7 6.9 30.3 1.6 8.5 5.5 3.1 2 1 1 3 3 3 0 Laminin Domain II DUF3584 PF12128.3 ABX12473.1 - 5.2 4.2 40.2 1.4 6.1 20.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) IFT57 PF10498.4 ABX12473.1 - 5.5 5.6 44.1 0.44 9.2 24.0 2.7 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF948 PF06103.6 ABX12473.1 - 5.5 6.9 18.1 0.52 10.2 2.5 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) tRNA-synt_1f PF01921.13 ABX12474.1 - 2.4e-106 355.4 0.1 5.9e-106 354.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1g PF09334.6 ABX12474.1 - 0.083 11.5 0.0 0.26 9.8 0.0 1.9 1 0 0 1 1 1 0 tRNA synthetases class I (M) Radical_SAM PF04055.16 ABX12475.1 - 8.2e-20 71.6 0.1 3.5e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 ABX12475.1 - 8.2e-08 32.1 0.0 4.8e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ABX12475.1 - 0.005 16.9 0.2 0.081 13.0 0.1 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SHOCT PF09851.4 ABX12475.1 - 1.1 8.8 4.4 2.3 7.8 0.3 2.4 2 0 0 2 2 2 0 Short C-terminal domain HC2 PF07382.6 ABX12476.1 - 0.00022 21.1 39.5 0.00024 21.0 27.4 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Mt_ATP-synt_B PF05405.9 ABX12476.1 - 1.3 8.4 8.9 2.5 7.5 6.2 1.6 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Effector_1 PF04518.7 ABX12476.1 - 1.4 7.8 6.8 0.85 8.5 3.5 1.6 1 1 0 1 1 1 0 Effector from type III secretion system ScpA_ScpB PF02616.9 ABX12476.1 - 1.9 7.9 15.2 2.2 7.8 10.5 1.0 1 0 0 1 1 1 0 ScpA/B protein DUF2413 PF10310.4 ABX12476.1 - 2.1 7.0 18.0 2.1 7.1 12.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) vMSA PF00695.14 ABX12476.1 - 2.5 7.2 5.4 2.8 7.0 3.7 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus MCPVI PF02993.9 ABX12476.1 - 4.9 7.2 10.7 5.2 7.1 7.4 1.0 1 0 0 1 1 1 0 Minor capsid protein VI Na_H_Exchanger PF00999.16 ABX12477.1 - 6.3e-66 222.4 56.1 8e-66 222.0 38.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PspB PF06667.7 ABX12477.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 Phage shock protein B AIRS_C PF02769.17 ABX12478.1 - 6.6e-22 78.1 0.0 1.2e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 ABX12478.1 - 7.9e-17 61.2 0.9 1.8e-16 60.1 0.6 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PAC2 PF09754.4 ABX12479.1 - 5.1e-40 137.6 0.0 6.3e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 PAC2 family 7TMR-HDED PF07697.6 ABX12479.1 - 0.091 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 7TM-HD extracellular DUF3150 PF11348.3 ABX12480.1 - 0.04 13.0 5.0 0.18 10.8 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3150) Cortex-I_coil PF09304.5 ABX12480.1 - 0.3 11.1 23.1 0.54 10.3 2.7 3.3 2 1 1 3 3 3 0 Cortexillin I, coiled coil HTH_45 PF14947.1 ABX12481.1 - 0.0079 15.9 0.4 0.012 15.4 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 ABX12481.1 - 0.0092 15.6 0.3 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) DUF3116 PF11313.3 ABX12481.1 - 0.049 13.2 0.4 0.11 12.1 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3116) P-II PF00543.17 ABX12482.1 - 9.8e-10 38.8 0.4 1.5e-09 38.1 0.3 1.3 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II P-II PF00543.17 ABX12483.1 - 1.7e-13 50.8 0.7 2.2e-13 50.5 0.5 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Ammonium_transp PF00909.16 ABX12484.1 - 8.1e-113 376.8 34.6 9.2e-113 376.7 24.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Na_Ca_ex PF01699.19 ABX12486.1 - 5.8e-47 158.8 33.7 6.1e-27 93.9 9.7 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PmbA_TldD PF01523.11 ABX12487.1 - 8.3e-54 182.8 0.1 1.1e-53 182.4 0.1 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Pyr_redox PF00070.22 ABX12487.1 - 0.038 14.4 0.6 3 8.2 0.4 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2969 PF11184.3 ABX12487.1 - 2.9 8.0 9.2 10 6.3 4.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2969) Radical_SAM PF04055.16 ABX12488.1 - 9.6e-21 74.6 1.8 1.1e-20 74.4 0.4 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Glyco_hydro_35 PF01301.14 ABX12488.1 - 0.062 12.6 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 KdpD PF02702.12 ABX12488.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Radical_SAM PF04055.16 ABX12489.1 - 5.3e-12 46.2 0.0 9.3e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily BATS PF06968.8 ABX12489.1 - 0.014 15.2 0.1 0.034 13.9 0.1 1.6 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain Sec7_N PF12783.2 ABX12489.1 - 0.05 13.0 0.3 0.11 11.9 0.2 1.7 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SpoU_sub_bind PF08032.7 ABX12489.1 - 0.097 12.8 0.6 6.6 6.9 0.0 3.3 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Trypsin_2 PF13365.1 ABX12490.1 - 5.1e-22 78.1 0.1 9e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 ABX12490.1 - 2.3e-12 46.6 0.4 5.6e-12 45.3 0.3 1.7 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.21 ABX12490.1 - 3.1e-12 46.5 0.0 6.6e-12 45.4 0.0 1.5 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.4 ABX12490.1 - 0.0025 16.3 0.5 0.018 13.5 0.2 1.9 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S29 PF02907.10 ABX12490.1 - 0.0034 16.9 0.1 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Peptidase_S32 PF05579.8 ABX12490.1 - 0.065 12.1 0.9 4.5 6.1 0.2 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S7 PF00949.16 ABX12490.1 - 0.15 11.4 0.7 0.26 10.6 0.5 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease VirB8 PF04335.8 ABX12490.1 - 0.17 11.4 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 VirB8 protein Glycos_transf_2 PF00535.21 ABX12491.1 - 2.3e-30 105.5 0.0 3e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 ABX12491.1 - 2.6e-19 69.9 0.0 3.4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 ABX12491.1 - 5.2e-11 42.1 0.0 8.8e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 ABX12491.1 - 9.9e-08 31.3 0.0 1.3e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 ABX12491.1 - 3.8e-05 23.9 0.0 6.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 ABX12491.1 - 0.0007 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Polyketide_cyc2 PF10604.4 ABX12492.1 - 1.6e-11 44.5 0.0 1.8e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 ABX12492.1 - 3e-08 33.7 0.1 4.4e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.8 ABX12492.1 - 0.015 14.9 1.5 0.043 13.4 1.0 1.7 1 1 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) DUF1857 PF08982.6 ABX12492.1 - 0.037 13.6 0.1 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) tRNA_bind PF01588.15 ABX12493.1 - 1.7e-21 75.8 0.0 2.2e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Putative tRNA binding domain TBP PF00352.16 ABX12494.1 - 3.7e-61 202.4 0.0 2.5e-30 103.6 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 ABX12494.1 - 7.3e-07 29.1 0.0 0.00055 19.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF1512 PF07431.7 ABX12495.1 - 1.8e-97 326.3 5.1 2e-97 326.1 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1512) DnaJ_CXXCXGXG PF00684.14 ABX12496.1 - 0.041 13.9 2.2 0.068 13.2 1.5 1.4 1 1 0 1 1 1 0 DnaJ central domain SIR2 PF02146.12 ABX12496.1 - 0.12 12.1 0.6 0.13 11.9 0.4 1.0 1 0 0 1 1 1 0 Sir2 family DUF4182 PF13790.1 ABX12496.1 - 0.15 11.9 2.7 0.54 10.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) PADR1 PF08063.7 ABX12496.1 - 0.44 9.9 2.7 2.4 7.6 0.0 2.1 1 1 1 2 2 2 0 PADR1 (NUC008) domain zf-H2C2 PF09337.5 ABX12496.1 - 2.7 7.4 4.8 2.6 7.5 0.7 2.1 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger Peptidase_M24 PF00557.19 ABX12497.1 - 2.9e-42 144.5 0.4 1.4e-41 142.3 0.3 1.8 1 1 0 1 1 1 1 Metallopeptidase family M24 Utp13 PF08625.6 ABX12497.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain zf-C3HC4_3 PF13920.1 ABX12498.1 - 0.0066 16.0 0.8 0.0091 15.6 0.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 ABX12498.1 - 0.024 14.4 1.6 0.03 14.1 1.1 1.1 1 0 0 1 1 1 0 Double zinc ribbon FHIPEP PF00771.15 ABX12498.1 - 0.06 11.6 0.0 0.06 11.6 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family IncA PF04156.9 ABX12498.1 - 0.12 12.0 0.3 0.12 11.9 0.2 1.1 1 0 0 1 1 1 0 IncA protein zf-ribbon_3 PF13248.1 ABX12498.1 - 0.12 11.6 3.5 0.92 8.8 0.8 2.0 1 1 1 2 2 2 0 zinc-ribbon domain DUF1272 PF06906.6 ABX12498.1 - 0.12 12.2 1.7 0.18 11.6 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) CTV_P6 PF06706.6 ABX12498.1 - 0.24 10.9 5.4 0.33 10.4 3.7 1.2 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein TF_Zn_Ribbon PF08271.7 ABX12498.1 - 0.27 10.5 6.1 2.5 7.4 1.0 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding DUF3784 PF12650.2 ABX12498.1 - 0.31 11.0 3.4 0.36 10.8 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) P12 PF12669.2 ABX12498.1 - 5.9 7.1 8.4 0.26 11.5 0.4 2.1 2 0 0 2 2 2 0 Virus attachment protein p12 family Phage_integrase PF00589.17 ABX12499.1 - 2.4e-05 24.0 1.6 9.6e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.12 ABX12499.1 - 0.047 13.8 0.4 0.67 10.1 0.0 2.8 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 ABX12499.1 - 0.061 13.6 1.0 1.1 9.6 0.0 3.1 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain DUF2681 PF10883.3 ABX12499.1 - 0.31 11.2 4.3 0.98 9.6 2.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) zf-C2H2_2 PF12756.2 ABX12500.1 - 0.075 13.1 1.4 0.14 12.2 0.2 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Methylase_S PF01420.14 ABX12501.1 - 3.3e-29 102.0 21.4 1.2e-17 64.3 4.9 2.3 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain N6_Mtase PF02384.11 ABX12502.1 - 1.8e-102 342.5 0.9 2.4e-102 342.1 0.6 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.3 ABX12502.1 - 1e-23 84.2 2.9 1e-23 84.2 2.0 3.1 3 1 0 3 3 3 1 HsdM N-terminal domain UPF0020 PF01170.13 ABX12502.1 - 9.9e-08 31.7 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 ABX12502.1 - 1.8e-06 27.9 0.0 3.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Macro PF01661.16 ABX12502.1 - 0.0016 18.3 0.1 0.074 12.9 0.0 2.5 2 0 0 2 2 2 1 Macro domain KorB PF08535.5 ABX12502.1 - 0.042 14.0 0.1 0.2 11.8 0.1 2.2 1 0 0 1 1 1 0 KorB domain Cnd3 PF12719.2 ABX12502.1 - 0.048 12.6 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain MTS PF05175.9 ABX12502.1 - 0.055 12.8 0.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methylase_S PF01420.14 ABX12503.1 - 2.8e-45 154.3 19.5 1.6e-30 106.2 2.0 2.4 2 1 0 2 2 2 2 Type I restriction modification DNA specificity domain HSDR_N PF04313.9 ABX12504.1 - 3.8e-19 69.1 0.1 3.8e-19 69.1 0.1 2.4 2 1 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.10 ABX12504.1 - 3.6e-13 49.7 0.3 3.6e-13 49.7 0.2 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ABX12504.1 - 0.00016 21.2 0.2 0.058 12.8 0.0 3.1 3 1 0 3 3 3 2 DEAD/DEAH box helicase PPDFL PF15060.1 ABX12504.1 - 0.056 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Differentiation and proliferation regulator DUF45 PF01863.12 ABX12505.1 - 6.8e-38 130.5 6.2 2.8e-32 112.1 0.3 2.0 1 1 1 2 2 2 2 Protein of unknown function DUF45 WLM PF08325.5 ABX12505.1 - 8.7e-06 25.7 0.7 1.6e-05 24.8 0.0 1.7 2 1 0 2 2 2 1 WLM domain SprT-like PF10263.4 ABX12505.1 - 0.00014 21.5 0.0 0.00024 20.7 0.0 1.5 1 1 0 1 1 1 1 SprT-like family DUF955 PF06114.8 ABX12505.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF955) RuvC PF02075.12 ABX12505.1 - 0.033 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC Ribosomal_S24e PF01282.14 ABX12505.1 - 0.038 13.7 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein S24e N6_Mtase PF02384.11 ABX12506.1 - 1.2e-28 100.1 0.1 2.4e-28 99.1 0.1 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase HSDR_N_2 PF13588.1 ABX12506.1 - 2.7e-20 72.2 0.5 6.5e-20 71.0 0.3 1.7 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) Methyltransf_26 PF13659.1 ABX12506.1 - 1e-16 61.0 0.0 1.6e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methylase_S PF01420.14 ABX12506.1 - 7.9e-14 51.9 6.5 7.9e-14 51.9 4.5 2.7 3 1 0 3 3 3 1 Type I restriction modification DNA specificity domain Methyltransf_31 PF13847.1 ABX12506.1 - 1.3e-12 47.5 0.1 9.4e-12 44.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX12506.1 - 1.7e-09 38.2 0.0 3.8e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ABX12506.1 - 1.9e-09 37.1 0.0 8.2e-09 35.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 ABX12506.1 - 9.2e-09 35.1 0.0 2.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 ABX12506.1 - 4e-06 26.6 0.0 9.6e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ABX12506.1 - 4.6e-05 22.6 0.2 4.6e-05 22.6 0.2 2.1 3 0 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 ABX12506.1 - 5.4e-05 22.8 0.0 0.00013 21.5 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 ABX12506.1 - 6.3e-05 22.6 0.4 0.00039 20.0 0.0 2.4 2 1 1 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 ABX12506.1 - 0.00023 20.6 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 ABX12506.1 - 0.00042 20.7 0.0 0.0017 18.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ABX12506.1 - 0.0018 18.5 0.0 0.0069 16.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.14 ABX12506.1 - 0.008 16.1 0.1 0.028 14.3 0.1 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 ABX12506.1 - 0.089 11.8 3.5 0.12 11.4 0.1 2.8 4 0 0 4 4 4 0 Putative methyltransferase USP7_ICP0_bdg PF12436.3 ABX12508.1 - 0.013 14.7 0.6 0.021 14.0 0.4 1.3 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 Phage_integrase PF00589.17 ABX12509.1 - 1.6e-17 63.7 0.6 3e-17 62.8 0.4 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.1 ABX12509.1 - 0.0002 21.6 2.5 0.0019 18.5 0.1 2.7 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.12 ABX12509.1 - 0.0009 19.3 2.8 4.3 7.5 0.1 3.4 2 1 0 2 2 2 2 Phage integrase, N-terminal SAM-like domain Abi_2 PF07751.6 ABX12511.1 - 0.0053 16.9 0.4 0.69 10.0 0.3 2.2 1 1 0 1 1 1 1 Abi-like protein H_kinase_N PF12282.3 ABX12511.1 - 0.028 14.0 0.2 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Signal transduction histidine kinase Dynein_light PF01221.13 ABX12511.1 - 0.095 12.7 0.1 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Dynein light chain type 1 Sucrose_synth PF00862.14 ABX12511.1 - 0.12 10.3 0.0 0.15 9.9 0.0 1.1 1 0 0 1 1 1 0 Sucrose synthase A2M_N PF01835.14 ABX12512.1 - 7.6e-22 77.4 9.4 0.00036 20.7 0.0 7.9 7 0 0 7 7 7 5 MG2 domain LTD PF00932.14 ABX12512.1 - 6.1e-13 48.8 0.6 6.1e-13 48.8 0.4 2.7 3 0 0 3 3 3 1 Lamin Tail Domain Reeler PF02014.11 ABX12512.1 - 0.065 13.4 0.1 3.6 7.8 0.1 3.7 3 0 0 3 3 3 0 Reeler domain DUF367 PF04034.8 ABX12513.1 - 8.3e-36 122.4 0.0 1.1e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 ABX12513.1 - 3.8e-07 29.5 0.0 6.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI WavE PF07507.6 ABX12513.1 - 0.056 12.3 0.1 0.066 12.0 0.1 1.1 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis SBP_bac_5 PF00496.17 ABX12514.1 - 3.9e-26 91.7 6.4 7.3e-22 77.6 0.0 3.4 3 1 0 3 3 3 2 Bacterial extracellular solute-binding proteins, family 5 Middle Mrr_cat PF04471.7 ABX12515.1 - 0.00028 20.6 0.0 0.00049 19.8 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Hjc PF01870.13 ABX12515.1 - 0.0028 17.2 0.1 0.0048 16.4 0.1 1.4 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) NERD PF08378.6 ABX12515.1 - 0.0072 16.5 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Nuclease-related domain DUF2070 PF09843.4 ABX12516.1 - 2.4e-47 160.7 0.0 4e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Caveolin PF01146.12 ABX12516.1 - 0.36 10.4 5.6 0.36 10.4 1.2 2.3 2 0 0 2 2 2 0 Caveolin Auto_anti-p27 PF06677.7 ABX12517.1 - 4.5e-10 39.1 2.4 7.6e-10 38.4 1.6 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1178 PF06676.6 ABX12517.1 - 0.096 12.8 0.7 0.11 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Prim_Zn_Ribbon PF08273.7 ABX12517.1 - 0.23 11.5 3.5 0.57 10.2 2.5 1.5 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase DUF3571 PF12095.3 ABX12517.1 - 1 9.6 3.5 0.47 10.7 1.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) SUI1 PF01253.17 ABX12518.1 - 6.1e-22 77.2 0.2 7.4e-22 76.9 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Abi PF02517.11 ABX12519.1 - 7.9e-12 45.1 9.8 7.9e-12 45.1 6.8 2.6 1 1 1 2 2 2 1 CAAX protease self-immunity TFIIB PF00382.14 ABX12520.1 - 3.7e-37 125.9 5.3 5.4e-18 64.5 0.7 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 ABX12520.1 - 7.2e-14 50.8 2.4 1.2e-13 50.0 1.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 ABX12520.1 - 0.00019 20.5 3.7 0.00032 19.7 2.6 1.4 1 0 0 1 1 1 1 zinc-ribbon domain Sigma70_r4 PF04545.11 ABX12520.1 - 0.0002 20.5 0.0 0.082 12.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-70, region 4 Cyclin_N PF00134.18 ABX12520.1 - 0.0028 17.1 0.1 0.044 13.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 ABX12520.1 - 0.0052 16.6 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain HTH_AsnC-type PF13404.1 ABX12520.1 - 0.006 16.1 0.1 0.26 10.8 0.0 2.8 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain DZR PF12773.2 ABX12520.1 - 0.025 14.4 1.3 0.055 13.2 0.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon Cys_rich_CPCC PF14206.1 ABX12520.1 - 0.039 13.5 0.3 0.076 12.5 0.2 1.5 1 0 0 1 1 1 0 Cysteine-rich CPCC HTH_23 PF13384.1 ABX12520.1 - 0.052 13.2 0.3 0.41 10.3 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain zf-HIT PF04438.11 ABX12520.1 - 0.061 12.9 5.6 0.18 11.4 0.7 2.5 2 0 0 2 2 2 0 HIT zinc finger GCC2_GCC3 PF07699.8 ABX12520.1 - 0.12 11.9 2.3 0.24 11.0 1.6 1.5 1 0 0 1 1 1 0 GCC2 and GCC3 LacI PF00356.16 ABX12520.1 - 0.22 11.1 1.4 1.6 8.4 0.1 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Desulfoferrod_N PF06397.7 ABX12520.1 - 0.26 10.7 1.7 0.56 9.6 1.1 1.6 1 1 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zinc_ribbon_2 PF13240.1 ABX12520.1 - 0.28 10.7 6.9 4.2 6.9 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC_5 PF14787.1 ABX12520.1 - 0.83 9.1 4.7 3.2 7.2 3.0 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger NOB1_Zn_bind PF08772.6 ABX12520.1 - 3.9 7.3 5.4 9.1 6.1 0.3 2.6 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like CofC PF01983.11 ABX12521.1 - 2.2e-22 79.0 4.5 2.9e-22 78.6 3.1 1.0 1 0 0 1 1 1 1 Guanylyl transferase CofC like NTP_transf_3 PF12804.2 ABX12521.1 - 2.7e-05 24.3 0.0 3.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF3993 PF13158.1 ABX12521.1 - 0.12 12.2 2.2 0.65 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) UPF0052 PF01933.13 ABX12522.1 - 5.2e-49 167.1 0.0 6.9e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PCI PF01399.22 ABX12522.1 - 0.097 12.9 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 PCI domain FH2 PF02181.18 ABX12524.1 - 0.013 14.3 0.3 0.013 14.3 0.2 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain Phage_DsbA PF11126.3 ABX12524.1 - 0.014 15.4 0.3 0.022 14.8 0.2 1.4 1 0 0 1 1 1 0 Transcriptional regulator DsbA Methyltransf_23 PF13489.1 ABX12525.1 - 5.1e-21 75.0 0.0 6.2e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ABX12525.1 - 2.3e-20 72.7 0.1 3e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ABX12525.1 - 1.9e-19 69.9 0.0 5.2e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ABX12525.1 - 6.3e-15 55.4 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX12525.1 - 7e-15 55.5 0.0 1.2e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ABX12525.1 - 5.8e-13 49.0 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 ABX12525.1 - 3.7e-10 39.5 0.0 4.5e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 ABX12525.1 - 5.7e-10 38.3 0.1 1.3e-09 37.1 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 ABX12525.1 - 7.5e-10 38.1 0.4 2.3e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Ubie_methyltran PF01209.13 ABX12525.1 - 1.1e-06 27.9 2.1 3e-06 26.5 0.1 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 ABX12525.1 - 1.2e-06 27.9 0.0 1.5e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW DOT1 PF08123.8 ABX12525.1 - 3.7e-06 26.3 0.0 0.00045 19.5 0.0 2.2 1 1 0 2 2 2 1 Histone methylation protein DOT1 CMAS PF02353.15 ABX12525.1 - 1.3e-05 24.4 0.3 1.8e-05 24.0 0.2 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 ABX12525.1 - 4.8e-05 22.7 0.0 7.9e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 ABX12525.1 - 0.00043 20.2 0.0 0.00091 19.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ABX12525.1 - 0.00073 19.1 0.0 0.00099 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.7 ABX12525.1 - 0.0013 17.7 0.0 0.0021 16.9 0.0 1.3 1 1 0 1 1 1 1 DREV methyltransferase AdoMet_MTase PF07757.8 ABX12525.1 - 0.0018 18.3 0.6 0.0035 17.4 0.0 1.8 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase Methyltransf_5 PF01795.14 ABX12525.1 - 0.0035 16.6 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 MraW methylase family CheR PF01739.13 ABX12525.1 - 0.0047 16.2 0.0 0.046 12.9 0.0 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.1 ABX12525.1 - 0.009 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 ABX12525.1 - 0.05 12.7 0.1 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase FlgD_ig PF13860.1 ABX12526.1 - 0.00018 21.1 0.1 0.05 13.3 0.0 2.8 2 0 0 2 2 2 2 FlgD Ig-like domain DUF4363 PF14276.1 ABX12526.1 - 0.00044 19.9 4.3 0.02 14.6 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4363) Cytochrom_B562 PF07361.6 ABX12526.1 - 0.52 10.7 4.1 4.9 7.6 0.0 3.8 4 0 0 4 4 4 0 Cytochrome b562 FAD_oxidored PF12831.2 ABX12527.1 - 2.4e-16 59.8 0.1 3.2e-16 59.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 ABX12527.1 - 4.1e-15 55.5 0.4 2.5e-08 33.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 ABX12527.1 - 3.9e-13 48.8 0.4 1.8e-07 30.1 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 ABX12527.1 - 1.7e-12 46.9 0.5 9e-09 34.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 ABX12527.1 - 1.8e-11 43.7 0.8 1.5e-10 40.6 0.5 2.1 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 ABX12527.1 - 3e-10 39.1 0.7 3.1e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 ABX12527.1 - 1.1e-09 38.5 0.2 2e-09 37.6 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ABX12527.1 - 1e-08 34.5 0.1 1.7e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ABX12527.1 - 1.2e-07 32.0 0.2 1.8e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ABX12527.1 - 2.4e-07 29.9 0.9 7.8e-07 28.2 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 ABX12527.1 - 4.4e-07 29.2 4.0 2.6e-06 26.7 2.8 2.0 1 1 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 ABX12527.1 - 6.3e-06 26.1 0.1 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ABX12527.1 - 1e-05 25.8 1.9 0.0033 17.7 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 ABX12527.1 - 0.00089 18.8 0.3 0.0034 16.9 0.0 2.0 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 ABX12527.1 - 0.0011 18.9 0.1 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.1 ABX12527.1 - 0.0078 16.4 0.1 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 ABX12527.1 - 0.011 15.3 0.0 0.041 13.5 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.13 ABX12527.1 - 0.018 13.3 0.6 2.7 6.2 0.1 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor GMC_oxred_N PF00732.14 ABX12527.1 - 0.025 13.7 0.8 0.31 10.1 0.1 2.1 1 1 1 2 2 2 0 GMC oxidoreductase DUF3797 PF12677.2 ABX12528.1 - 0.0044 16.6 0.1 0.0064 16.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3797) zf-ribbon_3 PF13248.1 ABX12528.1 - 0.0044 16.1 0.3 0.0091 15.1 0.2 1.6 1 1 0 1 1 1 1 zinc-ribbon domain GFA PF04828.9 ABX12528.1 - 0.06 13.2 0.9 0.49 10.3 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ISL3 PF14690.1 ABX12528.1 - 0.075 13.0 1.1 0.18 11.8 0.8 1.9 1 1 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 ABX12528.1 - 0.1 12.3 0.7 0.35 10.7 0.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon DNA_ligase_ZBD PF03119.11 ABX12528.1 - 0.13 12.0 0.2 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF1451 PF07295.6 ABX12528.1 - 0.14 11.8 0.4 1.4 8.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) Rubredoxin PF00301.15 ABX12528.1 - 0.27 11.1 1.6 0.7 9.8 0.4 1.9 2 0 0 2 2 2 0 Rubredoxin zinc_ribbon_2 PF13240.1 ABX12528.1 - 0.36 10.3 2.5 0.82 9.2 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF99 PF01949.11 ABX12529.1 - 3.3e-59 199.1 0.0 4e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF99 adh_short_C2 PF13561.1 ABX12530.1 - 5.4e-40 137.6 0.4 6.5e-40 137.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ABX12530.1 - 5.5e-31 107.7 0.1 7.5e-31 107.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ABX12530.1 - 5e-09 36.0 0.1 7e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ABX12530.1 - 6.3e-06 26.3 0.0 9.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ABX12530.1 - 2.9e-05 23.6 0.5 4.6e-05 22.9 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ABX12530.1 - 0.0002 20.3 1.3 0.00026 19.9 0.9 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 ABX12530.1 - 0.00078 19.8 0.6 0.0015 18.9 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 ABX12530.1 - 0.0034 17.0 0.2 0.0055 16.3 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 ABX12530.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DFP PF04127.10 ABX12530.1 - 0.013 15.1 0.2 0.021 14.4 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_2 PF03446.10 ABX12531.1 - 2.2e-41 141.4 0.8 3.2e-41 140.8 0.5 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ABX12531.1 - 3.9e-20 72.1 0.1 5.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.7 ABX12531.1 - 2e-09 37.0 0.3 4e-09 36.0 0.2 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 ABX12531.1 - 3.1e-09 37.1 1.0 7.1e-09 35.9 0.4 1.8 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 ABX12531.1 - 2.6e-08 33.2 0.2 3.9e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 ABX12531.1 - 5.1e-07 29.2 0.1 9.4e-07 28.3 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 ABX12531.1 - 7.9e-06 26.0 0.2 1.6e-05 25.0 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 ABX12531.1 - 3.5e-05 23.5 0.6 0.0005 19.8 0.4 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 ABX12531.1 - 0.00095 18.5 1.3 0.0037 16.6 0.1 2.2 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 ABX12531.1 - 0.0016 18.1 2.1 0.0017 18.0 0.6 1.8 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_C PF03720.10 ABX12531.1 - 0.0018 18.3 0.1 0.0043 17.1 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Rossmann-like PF10727.4 ABX12531.1 - 0.0025 17.5 0.3 0.0067 16.1 0.1 1.7 2 0 0 2 2 2 1 Rossmann-like domain NAD_binding_10 PF13460.1 ABX12531.1 - 0.003 17.5 0.2 0.0074 16.3 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_7 PF13241.1 ABX12531.1 - 0.0038 17.4 0.5 0.0082 16.3 0.2 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding GFO_IDH_MocA PF01408.17 ABX12531.1 - 0.0093 16.4 0.1 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 ABX12531.1 - 0.011 15.7 0.6 0.063 13.2 0.3 2.4 1 1 1 2 2 2 0 TrkA-N domain DAO PF01266.19 ABX12531.1 - 0.071 11.9 0.1 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase CoA_binding PF02629.14 ABX12531.1 - 0.21 12.0 1.7 0.59 10.6 0.5 2.2 2 0 0 2 2 2 0 CoA binding domain zf-H2C2_5 PF13909.1 ABX12533.1 - 0.00018 21.5 1.8 0.00034 20.6 1.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 ABX12533.1 - 0.0022 18.2 1.3 0.0041 17.3 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ABX12533.1 - 0.005 17.0 0.8 0.0095 16.2 0.6 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger DUF3921 PF13060.1 ABX12534.1 - 0.067 13.0 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) Thioredoxin_4 PF13462.1 ABX12535.1 - 6.9e-34 117.2 0.0 8.6e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 ABX12535.1 - 4.1e-16 59.1 0.7 7.1e-14 51.8 0.5 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 ABX12535.1 - 1.2e-05 25.5 0.0 2.4e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Ephrin_lbd PF01404.14 ABX12535.1 - 0.0076 16.0 0.1 0.011 15.4 0.1 1.2 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Thioredoxin_5 PF13743.1 ABX12535.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.1 ABX12535.1 - 0.026 14.6 0.0 0.77 9.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like DUF3169 PF11368.3 ABX12536.1 - 0.0083 15.3 1.3 0.0083 15.3 0.9 1.8 1 1 0 2 2 2 1 Protein of unknown function (DUF3169) DUF555 PF04475.7 ABX12536.1 - 0.037 14.0 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF555) Exosortase_EpsH PF09721.5 ABX12537.1 - 5.2e-06 25.8 29.0 1.1e-05 24.8 20.1 1.5 1 1 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) IMS PF00817.15 ABX12538.1 - 2.7e-42 144.0 0.2 4.5e-41 140.1 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 ABX12538.1 - 1.6e-15 57.1 1.1 1.6e-15 57.1 0.7 1.6 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 ABX12538.1 - 8.2e-08 31.8 0.1 1.9e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.1 ABX12538.1 - 0.0086 16.2 0.0 0.073 13.2 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.3 ABX12538.1 - 0.014 15.3 0.1 0.08 12.8 0.0 2.1 2 1 0 2 2 2 0 Pathogenicity locus GLTP PF08718.6 ABX12538.1 - 0.023 14.7 2.4 0.16 12.0 0.7 2.2 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) DNA_pol_lambd_f PF10391.4 ABX12538.1 - 0.045 13.3 0.0 0.19 11.3 0.0 2.1 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda ArsC PF03960.10 ABX12538.1 - 0.13 12.2 4.0 3.2 7.8 0.2 2.7 1 1 1 2 2 2 0 ArsC family PB1 PF00564.19 ABX12539.1 - 0.053 13.1 1.1 0.072 12.7 0.7 1.2 1 0 0 1 1 1 0 PB1 domain Herpes_UL31 PF02718.9 ABX12539.1 - 0.065 11.9 0.8 0.074 11.7 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL31-like protein Viral_DNA_bi PF02236.12 ABX12539.1 - 0.11 12.7 1.9 5.7 7.1 0.1 2.1 1 1 1 2 2 2 0 Viral DNA-binding protein, all alpha domain Alba PF01918.16 ABX12540.1 - 4.2e-08 32.6 0.3 5.6e-08 32.2 0.2 1.2 1 0 0 1 1 1 1 Alba Methyltransf_17 PF12692.2 ABX12540.1 - 0.071 12.7 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase LysE PF01810.13 ABX12542.1 - 4e-26 91.4 15.1 5.1e-26 91.1 10.5 1.0 1 0 0 1 1 1 1 LysE type translocator PAC2 PF09754.4 ABX12543.1 - 4.4e-23 82.2 0.0 5.3e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 PAC2 family DS PF01916.12 ABX12544.1 - 2.4e-73 246.8 0.2 2.8e-73 246.6 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase NAD_binding_5 PF07994.7 ABX12545.1 - 3.6e-41 141.5 0.0 2.4e-40 138.8 0.0 1.9 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 ABX12545.1 - 9.3e-30 102.7 0.5 1.7e-29 101.8 0.1 1.6 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase CN_hydrolase PF00795.17 ABX12546.1 - 2.3e-17 62.9 0.0 7.3e-17 61.3 0.0 1.7 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase SMC_N PF02463.14 ABX12547.1 - 5e-51 173.0 53.1 4.2e-33 114.4 0.2 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 ABX12547.1 - 1.8e-16 60.2 0.0 7.6e-16 58.1 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 ABX12547.1 - 7.7e-15 55.7 30.1 7.7e-15 55.7 20.8 6.7 2 2 2 4 4 3 1 AAA domain AAA_29 PF13555.1 ABX12547.1 - 4.5e-06 26.0 0.0 1.2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 ABX12547.1 - 5.2e-05 23.3 44.4 0.0084 16.1 11.8 5.3 2 2 1 3 3 3 1 AAA domain IncA PF04156.9 ABX12547.1 - 7.1e-05 22.4 18.3 7.1e-05 22.4 12.7 7.1 2 2 4 6 6 5 3 IncA protein DUF2968 PF11180.3 ABX12547.1 - 0.0032 16.8 12.3 0.0032 16.8 8.5 6.4 2 2 3 6 6 6 1 Protein of unknown function (DUF2968) ABC_tran PF00005.22 ABX12547.1 - 0.015 15.6 1.3 0.015 15.6 0.9 6.6 3 3 0 3 3 1 0 ABC transporter AAA_16 PF13191.1 ABX12547.1 - 0.22 11.5 0.0 0.22 11.5 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain Reo_sigmaC PF04582.7 ABX12547.1 - 0.3 10.2 58.2 0.022 13.9 7.3 5.5 2 2 3 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 ABX12547.1 - 4.4 5.6 110.2 0.12 10.8 19.6 6.0 4 2 2 6 6 6 0 AAA domain ABC_tran PF00005.22 ABX12548.1 - 7.8e-34 116.9 0.0 1.1e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.7 ABX12548.1 - 2.2e-17 63.1 0.1 7.2e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.1 ABX12548.1 - 4.6e-08 33.3 2.2 6.9e-05 22.9 0.2 2.3 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 ABX12548.1 - 7.5e-06 25.2 2.5 0.012 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.1 ABX12548.1 - 7.1e-05 22.8 0.0 9.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 ABX12548.1 - 9.6e-05 21.9 0.0 0.0025 17.2 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain AAA_22 PF13401.1 ABX12548.1 - 0.00018 21.6 0.5 0.0053 16.8 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ABX12548.1 - 0.00022 20.6 0.1 0.00045 19.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 ABX12548.1 - 0.00037 20.8 0.6 0.001 19.3 0.1 2.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 ABX12548.1 - 0.00062 18.9 1.4 0.00076 18.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 ABX12548.1 - 0.00064 19.0 0.5 0.0091 15.2 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 ABX12548.1 - 0.0014 17.7 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 ABX12548.1 - 0.0014 18.7 0.2 0.022 14.9 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 ABX12548.1 - 0.0037 16.1 0.0 0.006 15.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 ABX12548.1 - 0.0039 17.9 0.1 0.03 15.1 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 ABX12548.1 - 0.0041 17.4 0.5 0.0068 16.7 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ABX12548.1 - 0.0062 15.9 0.0 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 ABX12548.1 - 0.0092 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 ABX12548.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 ABX12548.1 - 0.025 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 ABX12548.1 - 0.037 14.0 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF87 PF01935.12 ABX12548.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_33 PF13671.1 ABX12548.1 - 0.049 13.5 0.1 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ABX12548.1 - 0.055 13.6 0.1 0.19 11.9 0.0 2.0 2 1 0 2 2 1 0 RNA helicase AAA_13 PF13166.1 ABX12548.1 - 0.064 11.7 0.0 4.1 5.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 ABX12548.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_5 PF07728.9 ABX12548.1 - 0.083 12.6 0.1 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.7 ABX12548.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NACHT PF05729.7 ABX12548.1 - 0.13 11.9 0.0 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Methyltransf_33 PF10017.4 ABX12549.1 - 1e-44 151.4 1.0 1.8e-44 150.6 0.7 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 ABX12549.1 - 0.0012 19.1 0.0 0.0032 17.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_28 PF02636.12 ABX12549.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.6 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FMN_red PF03358.10 ABX12550.1 - 3e-33 114.4 0.0 3.6e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 ABX12550.1 - 4.6e-08 32.7 0.0 7.7e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold SPC25 PF06703.6 ABX12550.1 - 0.14 11.7 0.0 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Thioredoxin_4 PF13462.1 ABX12551.1 - 2.3e-34 118.7 0.1 3e-34 118.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 ABX12551.1 - 1.5e-10 40.9 1.5 3.6e-07 29.9 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 ABX12551.1 - 9.9e-07 28.9 0.0 2.3e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 ABX12551.1 - 2.4e-06 27.2 0.1 8.5e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 ABX12551.1 - 0.0034 17.4 0.1 0.13 12.3 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like HATPase_c PF02518.21 ABX12552.1 - 3.7e-22 78.1 0.1 6.1e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ABX12552.1 - 8.1e-12 44.9 0.1 2.1e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 ABX12552.1 - 3.1e-09 36.4 0.1 8.9e-09 34.9 0.1 1.8 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 ABX12552.1 - 0.00043 19.9 0.0 0.00098 18.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 ABX12552.1 - 0.00061 19.5 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain FGE-sulfatase PF03781.11 ABX12553.1 - 3.4e-49 167.5 2.9 6e-49 166.7 2.0 1.4 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 ABX12553.1 - 1.5e-12 48.0 0.0 7.1e-12 45.7 0.0 2.2 3 0 0 3 3 3 1 DinB superfamily ProRS-C_1 PF09180.6 ABX12554.1 - 5.4e-21 74.2 1.4 1.2e-20 73.1 0.5 2.1 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 ABX12554.1 - 9.5e-21 73.5 1.2 2.6e-20 72.1 0.8 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 ABX12554.1 - 5.5e-17 61.8 0.0 1.1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF2218 PF09981.4 ABX12555.1 - 0.068 13.3 0.1 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) PPDK_N PF01326.14 ABX12556.1 - 2.4e-16 59.7 0.0 3.3e-15 55.9 0.0 2.4 2 1 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 ABX12556.1 - 4.8e-14 51.6 0.0 8.7e-14 50.8 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Phasin_2 PF09361.5 ABX12556.1 - 0.093 12.7 0.0 0.37 10.8 0.0 2.0 1 0 0 1 1 1 0 Phasin protein DMA PF03474.9 ABX12556.1 - 0.16 11.8 1.2 6.3 6.7 0.1 2.9 3 0 0 3 3 3 0 DMRTA motif Peptidase_C26 PF07722.8 ABX12557.1 - 1.9e-27 96.1 0.0 6.3e-27 94.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.23 ABX12557.1 - 3.4e-19 69.0 0.0 4.2e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_5 PF13507.1 ABX12557.1 - 0.0013 17.7 0.4 0.63 8.8 0.0 2.6 1 1 1 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.9 ABX12557.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain NTP_transf_3 PF12804.2 ABX12558.1 - 4e-11 43.2 0.0 4.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 ABX12558.1 - 9.4e-11 41.4 0.5 4.9e-10 39.1 0.0 2.2 2 1 0 2 2 2 1 Nucleotidyl transferase IspD PF01128.14 ABX12558.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 ABX12558.1 - 0.063 12.9 0.1 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase Sulfatase PF00884.18 ABX12559.1 - 1.1e-25 90.4 0.0 7.8e-24 84.4 0.0 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ABX12559.1 - 0.00059 19.2 0.4 0.095 11.9 0.0 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2183 PF09949.4 ABX12559.1 - 0.023 14.5 0.1 0.62 10.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) DUF229 PF02995.12 ABX12559.1 - 0.044 12.2 0.0 0.057 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Orbi_VP5 PF00901.12 ABX12559.1 - 0.16 10.1 0.0 0.23 9.5 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Glyphos_transf PF04464.9 ABX12560.1 - 1.8e-19 69.7 11.1 2.7e-19 69.1 7.7 1.2 1 0 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase PA28_alpha PF02251.13 ABX12560.1 - 0.17 12.0 1.5 1.1 9.4 0.1 3.0 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit Sulfatase PF00884.18 ABX12561.1 - 2.9e-06 26.6 0.3 4.3e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 Sulfatase PspB PF06667.7 ABX12561.1 - 3.8 7.5 5.4 2.6 8.0 0.6 3.0 3 0 0 3 3 3 0 Phage shock protein B DUF4131 PF13567.1 ABX12561.1 - 6 6.2 6.9 4.8 6.5 1.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Hydrolase PF00702.21 ABX12562.1 - 1.7e-10 41.6 0.1 1.1e-09 38.9 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ABX12562.1 - 3.4e-08 33.8 0.1 4.9e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ABX12562.1 - 1.3e-06 28.7 0.0 2.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ABX12562.1 - 1.9e-05 24.3 0.1 0.0026 17.4 0.1 2.8 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase F420_ligase PF01996.11 ABX12563.1 - 1.8e-67 226.7 1.5 2.1e-67 226.5 1.1 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase PHP_C PF13263.1 ABX12564.1 - 5.2e-11 41.8 0.0 1.5e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 PHP-associated PHP PF02811.14 ABX12564.1 - 1.5e-05 24.8 0.0 2e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 PHP domain TusA PF01206.12 ABX12565.1 - 3.7e-22 77.7 0.0 4.1e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA PALP PF00291.20 ABX12566.1 - 1.9e-54 184.9 0.0 2.4e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme mit_SMPDase PF14724.1 ABX12567.1 - 0.014 13.2 0.4 0.013 13.3 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase GCV_H PF01597.14 ABX12567.1 - 0.038 13.6 0.5 0.085 12.5 0.1 1.8 1 1 0 1 1 1 0 Glycine cleavage H-protein DUF4404 PF14357.1 ABX12567.1 - 0.31 11.4 3.8 4.6 7.7 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) IMD PF08397.6 ABX12567.1 - 0.32 10.2 10.4 0.39 9.9 6.2 1.7 1 1 1 2 2 2 0 IRSp53/MIM homology domain EMP70 PF02990.11 ABX12567.1 - 0.39 9.1 3.4 0.34 9.3 2.1 1.3 1 1 0 1 1 1 0 Endomembrane protein 70 Med9 PF07544.8 ABX12567.1 - 2.2 8.0 7.9 2.7 7.8 0.8 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Pyr_redox_2 PF07992.9 ABX12568.1 - 2.1e-33 115.9 0.4 7.7e-33 114.0 0.3 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ABX12568.1 - 1.9e-18 66.6 1.4 1.6e-16 60.4 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ABX12568.1 - 7.6e-11 42.4 0.2 5.8e-08 33.0 0.0 2.9 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ABX12568.1 - 6e-08 31.9 2.9 0.00046 19.2 0.0 2.5 2 1 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 ABX12568.1 - 9.8e-07 27.9 0.3 0.0051 15.7 0.0 3.8 4 0 0 4 4 4 1 Glucose inhibited division protein A Thi4 PF01946.12 ABX12568.1 - 5.7e-05 22.3 0.0 0.001 18.2 0.0 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 ABX12568.1 - 7.1e-05 21.8 3.8 0.00048 19.0 0.1 2.7 2 1 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 ABX12568.1 - 8.6e-05 21.5 0.1 0.29 10.0 0.0 3.3 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 ABX12568.1 - 0.00032 19.8 1.7 0.015 14.3 0.0 2.6 2 1 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 ABX12568.1 - 0.0011 18.1 0.1 0.0021 17.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ABX12568.1 - 0.0017 18.3 0.2 0.012 15.6 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ABX12568.1 - 0.0045 15.5 2.3 0.031 12.7 0.1 2.7 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_7 PF13241.1 ABX12568.1 - 0.0057 16.9 1.3 0.055 13.7 0.3 2.4 2 2 0 2 2 2 1 Putative NAD(P)-binding XdhC_C PF13478.1 ABX12568.1 - 0.024 14.9 0.4 0.058 13.6 0.3 1.8 1 1 0 1 1 1 0 XdhC Rossmann domain NAD_binding_9 PF13454.1 ABX12568.1 - 0.074 12.8 5.5 12 5.6 0.1 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 ABX12568.1 - 0.087 11.7 0.5 28 3.4 0.1 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein CBS PF00571.23 ABX12569.1 - 1.6e-28 98.2 3.7 1.6e-14 53.3 0.1 2.3 2 0 0 2 2 2 2 CBS domain Arch_ATPase PF01637.13 ABX12569.1 - 0.028 14.1 3.4 0.039 13.6 2.3 1.3 1 1 0 1 1 1 0 Archaeal ATPase DUF3074 PF11274.3 ABX12569.1 - 0.051 13.1 0.7 0.062 12.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) PTH2 PF01981.11 ABX12569.1 - 0.19 11.4 3.1 0.14 11.9 0.5 1.8 1 1 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 CAP_assoc_N PF14504.1 ABX12569.1 - 1.7 8.3 6.5 15 5.3 0.0 2.7 1 1 2 3 3 3 0 CAP-associated N-terminal Usp PF00582.21 ABX12570.1 - 5.6e-27 94.6 0.0 6.9e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Ribosomal_S30AE PF02482.14 ABX12571.1 - 5e-08 33.2 0.6 6.4e-08 32.9 0.4 1.1 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein DUF3456 PF11938.3 ABX12571.1 - 0.017 15.0 0.3 0.02 14.9 0.2 1.1 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Ldh_1_N PF00056.18 ABX12572.1 - 5.1e-23 81.4 0.2 7.9e-23 80.8 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 ABX12572.1 - 1e-22 80.7 0.0 3.2e-22 79.1 0.0 1.8 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 ABX12572.1 - 1.6e-07 30.8 0.2 8.9e-06 25.1 0.0 2.4 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase Shikimate_DH PF01488.15 ABX12572.1 - 0.0069 16.4 0.2 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 ABX12572.1 - 0.0069 16.0 1.7 0.014 15.0 0.3 2.3 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 ABX12572.1 - 0.01 16.2 0.1 0.025 15.0 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 ABX12572.1 - 0.016 14.5 2.0 0.21 10.9 1.4 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IF3_C PF00707.17 ABX12573.1 - 0.047 13.4 0.4 0.14 11.9 0.3 1.8 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain Thi4 PF01946.12 ABX12574.1 - 3.5e-64 216.0 0.0 4.2e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 ABX12574.1 - 7.6e-15 54.6 0.3 3.7e-07 29.3 0.0 3.0 2 1 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.2 ABX12574.1 - 9.1e-10 38.1 0.1 1.6e-09 37.3 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 ABX12574.1 - 8.4e-09 34.7 0.1 1.3e-05 24.2 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ABX12574.1 - 1.7e-08 34.3 0.0 3.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 ABX12574.1 - 2.6e-07 30.0 0.0 4.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ABX12574.1 - 3.2e-07 30.4 0.0 5.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ABX12574.1 - 7.5e-07 27.9 0.0 1.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 ABX12574.1 - 3.2e-05 23.0 0.0 0.00025 20.0 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ABX12574.1 - 4.9e-05 23.4 0.1 8.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ABX12574.1 - 0.00035 19.5 0.1 0.00057 18.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 ABX12574.1 - 0.0038 17.0 0.1 0.0074 16.0 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 ABX12574.1 - 0.0051 17.1 0.1 0.017 15.5 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ABX12574.1 - 0.0089 14.6 0.0 0.99 7.9 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Amino_oxidase PF01593.19 ABX12574.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GDI PF00996.13 ABX12574.1 - 0.018 13.3 0.0 0.029 12.7 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor TrkA_N PF02254.13 ABX12574.1 - 0.032 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NIR_SIR PF01077.17 ABX12575.1 - 1.6e-41 141.2 0.0 1e-29 102.9 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 ABX12575.1 - 8.2e-31 105.4 0.1 3.9e-15 55.2 0.0 2.4 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Rhodanese PF00581.15 ABX12576.1 - 1.4e-35 122.0 0.0 6.1e-17 61.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain TPR_11 PF13414.1 ABX12577.1 - 2.4e-26 91.1 4.8 1.8e-11 43.4 0.0 4.5 5 0 0 5 5 4 2 TPR repeat TPR_1 PF00515.23 ABX12577.1 - 2.3e-24 83.9 3.8 6.4e-08 31.8 0.0 6.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 ABX12577.1 - 5.9e-24 82.0 6.3 5.7e-07 28.9 0.0 6.5 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 ABX12577.1 - 5.7e-18 64.6 0.4 2.5e-06 27.3 0.0 4.0 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ABX12577.1 - 2.6e-17 62.9 0.0 4.6e-08 33.5 0.0 4.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 ABX12577.1 - 5.2e-17 61.9 0.1 2.4e-07 31.0 0.0 4.0 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ABX12577.1 - 5.8e-16 57.2 0.3 0.00027 20.9 0.0 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ABX12577.1 - 1.4e-13 49.5 7.9 0.00058 19.4 0.0 6.1 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 ABX12577.1 - 7.2e-13 47.9 1.8 0.0063 17.0 0.0 5.5 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 ABX12577.1 - 3.2e-09 36.5 0.0 0.00019 21.1 0.0 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ABX12577.1 - 9.2e-09 35.1 4.9 0.87 10.1 0.0 6.1 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 ABX12577.1 - 5.8e-08 31.9 1.1 0.33 10.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 ABX12577.1 - 2.4e-07 30.7 0.2 2.1e-06 27.7 0.0 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 ABX12577.1 - 1.4e-05 24.8 0.3 0.39 10.6 0.0 4.0 2 1 2 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat HTH_27 PF13463.1 ABX12577.1 - 0.0024 18.1 0.1 0.0063 16.8 0.0 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain TPR_20 PF14561.1 ABX12577.1 - 0.0042 17.1 3.4 8 6.6 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TrmB PF01978.14 ABX12577.1 - 0.0051 16.4 0.3 1.3 8.7 0.0 2.9 2 1 1 3 3 2 1 Sugar-specific transcriptional regulator TrmB DUF424 PF04242.8 ABX12577.1 - 0.0054 16.7 0.5 0.26 11.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF424) YfiO PF13525.1 ABX12577.1 - 0.0074 15.7 0.4 1.5 8.2 0.0 2.9 2 1 0 3 3 3 1 Outer membrane lipoprotein Rapsyn_N PF10579.4 ABX12577.1 - 0.014 15.1 0.1 3.3 7.5 0.0 3.3 2 1 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.1 ABX12577.1 - 0.016 15.1 0.1 15 5.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 ABX12577.1 - 0.021 14.0 2.0 2.6 7.1 0.0 2.7 2 1 1 3 3 3 0 Coatomer epsilon subunit MIT PF04212.13 ABX12577.1 - 0.052 13.4 4.9 8.7 6.3 0.8 4.0 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ABX12577.1 - 0.08 12.7 1.5 14 5.5 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat TOM20_plant PF06552.7 ABX12577.1 - 0.088 12.3 2.3 0.22 11.0 0.0 2.5 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4398 PF14346.1 ABX12577.1 - 0.41 10.7 2.5 25 5.0 0.1 3.4 4 0 0 4 4 3 0 Domain of unknown function (DUF4398) DUF4363 PF14276.1 ABX12577.1 - 3.8 7.2 7.5 1.7 8.3 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Collagen PF01391.13 ABX12578.1 - 5e-61 202.1 232.2 6.1e-09 35.2 23.7 7.7 1 1 3 4 4 4 3 Collagen triple helix repeat (20 copies) TGS PF02824.16 ABX12580.1 - 5.8e-21 74.0 0.0 1.2e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 ABX12580.1 - 1.6e-20 73.1 0.2 4e-20 71.8 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ABX12580.1 - 1e-16 60.5 1.4 1.4e-13 50.4 0.0 2.3 2 1 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 ABX12580.1 - 4.7e-05 23.2 0.5 0.091 12.5 0.2 2.7 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.11 ABX12580.1 - 0.00028 20.0 0.0 0.00053 19.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 ABX12580.1 - 0.0016 17.6 0.3 0.0076 15.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arf PF00025.16 ABX12580.1 - 0.0016 17.7 1.4 0.044 13.0 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family ArgK PF03308.11 ABX12580.1 - 0.0031 16.3 0.3 0.079 11.7 0.1 2.4 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 ABX12580.1 - 0.0034 17.8 0.0 0.0088 16.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 ABX12580.1 - 0.0085 15.3 1.8 0.012 14.8 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.14 ABX12580.1 - 0.025 14.0 3.7 0.48 9.8 0.2 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 ABX12580.1 - 0.028 14.3 0.1 0.06 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 ABX12580.1 - 0.046 13.1 1.7 5.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Ras family AAA_33 PF13671.1 ABX12580.1 - 0.05 13.4 0.2 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain Hydrolase_3 PF08282.7 ABX12581.1 - 7.7e-33 114.1 2.4 1.3e-23 83.9 0.4 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 ABX12581.1 - 1.2e-07 31.3 0.1 0.00018 20.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 ABX12581.1 - 4.8e-07 30.1 2.7 2.9e-05 24.3 0.2 2.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ABX12581.1 - 5.6e-05 23.6 0.2 0.0053 17.2 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 ABX12581.1 - 8.5e-05 21.5 0.1 0.0012 17.7 0.1 2.0 1 1 0 1 1 1 1 Trehalose-phosphatase Response_reg PF00072.19 ABX12581.1 - 0.031 14.2 0.2 0.28 11.2 0.1 2.3 2 1 0 2 2 2 0 Response regulator receiver domain DUF2538 PF10804.3 ABX12581.1 - 0.041 13.7 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) Hydrolase_6 PF13344.1 ABX12581.1 - 0.047 13.5 0.1 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase tRNA-synt_1d PF00750.14 ABX12582.1 - 1.7e-38 132.3 1.9 6.5e-30 104.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 ABX12582.1 - 3e-28 98.1 0.4 4.2e-27 94.4 0.0 2.7 3 0 0 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 ABX12582.1 - 1e-14 54.8 0.0 3.4e-14 53.1 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 ABX12582.1 - 0.00018 20.7 0.0 0.00037 19.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 ABX12582.1 - 0.013 14.1 0.1 0.03 12.9 0.1 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (M) PNPase PF03726.9 ABX12582.1 - 0.14 12.4 5.1 7.1 6.9 0.4 3.1 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain PAD_porph PF04371.10 ABX12583.1 - 4.8e-23 81.7 0.4 1.1e-22 80.5 0.3 1.6 1 1 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.12 ABX12583.1 - 0.00045 19.4 0.0 0.00082 18.5 0.0 1.3 1 0 0 1 1 1 1 Amidinotransferase PTSIIA_gutA PF03829.8 ABX12583.1 - 0.099 12.3 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 PTS system glucitol/sorbitol-specific IIA component TF_Zn_Ribbon PF08271.7 ABX12585.1 - 0.047 13.0 4.1 0.33 10.2 2.9 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 ABX12585.1 - 0.13 11.8 3.1 0.78 9.2 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-B_box PF00643.19 ABX12585.1 - 0.5 10.3 3.1 5.2 7.0 0.4 2.1 2 0 0 2 2 2 0 B-box zinc finger zf-DBF PF07535.7 ABX12585.1 - 1.2 8.8 3.8 0.55 9.9 0.3 2.0 2 0 0 2 2 2 0 DBF zinc finger GCD14 PF08704.5 ABX12586.1 - 2.3e-37 128.8 0.1 2.9e-37 128.4 0.1 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 ABX12586.1 - 5.5e-12 45.6 0.1 8.6e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 ABX12586.1 - 6.1e-11 42.1 0.0 9.9e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX12586.1 - 3.4e-09 37.2 0.0 6.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 ABX12586.1 - 1.9e-07 31.8 0.0 4.8e-07 30.5 0.0 1.7 1 1 1 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ABX12586.1 - 6e-07 29.5 0.0 1.3e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ABX12586.1 - 1e-06 28.0 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 ABX12586.1 - 2.3e-06 26.8 0.0 3.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 ABX12586.1 - 2.6e-06 26.6 0.0 4.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 ABX12586.1 - 7.4e-06 25.2 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 ABX12586.1 - 1.7e-05 24.2 0.0 9.6e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 ABX12586.1 - 3e-05 24.4 0.0 8.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.12 ABX12586.1 - 0.00014 20.8 0.0 0.00023 20.1 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_12 PF08242.7 ABX12586.1 - 0.00017 22.0 0.0 0.0004 20.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 ABX12586.1 - 0.00038 19.9 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 ABX12586.1 - 0.005 17.1 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ABX12586.1 - 0.0057 15.7 0.0 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 ABX12586.1 - 0.0058 16.3 0.2 0.014 15.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 ABX12586.1 - 0.0092 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 ABX12586.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.1 ABX12586.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 ABX12586.1 - 0.035 14.0 0.1 0.053 13.5 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF43 PF01861.11 ABX12586.1 - 0.061 12.3 0.0 0.099 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 Carb_kinase PF01256.12 ABX12587.1 - 1.8e-46 158.3 0.3 2.2e-46 158.1 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 ABX12587.1 - 1.6e-08 34.0 0.0 2.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 ABX12587.1 - 1e-06 28.1 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Peptidase_M20 PF01546.23 ABX12588.1 - 4.6e-28 98.0 0.0 6.4e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ABX12588.1 - 3.9e-13 49.1 0.0 9.1e-13 47.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain WG_beta_rep PF14903.1 ABX12588.1 - 0.064 13.5 0.0 0.94 9.8 0.0 2.5 2 0 0 2 2 2 0 WG containing repeat Tox-PL-2 PF15643.1 ABX12588.1 - 0.095 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Papain fold toxin 2 DoxX PF07681.7 ABX12589.1 - 5.4e-13 49.1 3.9 5.4e-13 49.1 2.7 1.6 1 1 1 2 2 2 1 DoxX DoxX_2 PF13564.1 ABX12589.1 - 1.9e-05 24.5 4.2 2.9e-05 23.9 2.9 1.4 1 1 0 1 1 1 1 DoxX-like family DoxD PF04173.8 ABX12589.1 - 0.00038 20.1 4.1 0.00059 19.5 2.3 1.6 1 1 1 2 2 2 1 TQO small subunit DoxD Proteasome PF00227.21 ABX12590.1 - 1.8e-45 154.6 0.0 2.2e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PUA PF01472.15 ABX12591.1 - 3.6e-17 61.8 0.1 5.3e-17 61.3 0.1 1.3 1 0 0 1 1 1 1 PUA domain Homoserine_dh PF00742.14 ABX12592.1 - 9.1e-56 188.3 0.2 1.6e-55 187.5 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 ABX12592.1 - 1.6e-07 31.7 0.0 4.3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 ABX12592.1 - 9.1e-06 25.4 0.2 2.2e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SelR PF01641.13 ABX12593.1 - 8.5e-50 167.6 0.2 9.7e-50 167.4 0.2 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 ABX12593.1 - 0.037 14.0 3.5 0.21 11.6 2.5 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 ABX12593.1 - 0.047 13.5 0.6 8.4 6.2 0.2 2.3 2 0 0 2 2 2 0 C-terminal domain of RIG-I Elf1 PF05129.8 ABX12593.1 - 0.062 13.0 0.6 3 7.6 0.2 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 ABX12593.1 - 0.076 13.3 2.2 1.4 9.3 1.5 2.2 1 1 0 1 1 1 0 Restriction alleviation protein Lar DZR PF12773.2 ABX12593.1 - 0.14 12.0 4.5 6.2 6.7 0.3 2.4 2 1 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 ABX12593.1 - 0.51 9.6 7.8 2.5 7.4 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 ABX12593.1 - 0.58 9.9 4.5 7.6 6.3 0.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-BED PF02892.10 ABX12593.1 - 0.74 9.6 4.0 9.5 6.0 0.0 2.6 3 0 0 3 3 3 0 BED zinc finger zinc_ribbon_2 PF13240.1 ABX12593.1 - 1.9 8.0 9.8 4.5 6.8 0.8 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Thy1 PF02511.10 ABX12594.1 - 2.6e-29 101.9 2.8 8.7e-15 54.5 1.2 2.5 2 0 0 2 2 2 2 Thymidylate synthase complementing protein DUF106 PF01956.11 ABX12594.1 - 1.2 8.6 4.3 0.55 9.7 0.4 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF106 CHD5 PF04420.9 ABX12594.1 - 6.2 6.4 8.1 0.97 9.0 0.9 2.3 2 0 0 2 2 2 0 CHD5-like protein YtzH PF14165.1 ABX12594.1 - 7.9 6.7 8.4 8 6.7 0.7 3.1 3 1 1 4 4 4 0 YtzH-like protein Paramyxo_P PF01806.12 ABX12595.1 - 0.05 12.8 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region DUF948 PF06103.6 ABX12596.1 - 0.69 9.8 6.7 0.57 10.0 0.8 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) AMP-binding PF00501.23 ABX12597.1 - 3.3e-92 309.0 0.0 4.2e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ABX12597.1 - 1.1e-20 74.3 1.0 3.1e-20 72.9 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PAS_9 PF13426.1 ABX12598.1 - 7.7e-12 45.5 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 ABX12598.1 - 1e-09 38.1 0.0 1.6e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.5 ABX12598.1 - 1.9e-05 24.6 0.0 2.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 ABX12598.1 - 0.00098 19.1 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 PAS fold Retrotrans_gag PF03732.12 ABX12598.1 - 0.053 13.5 0.7 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein XPG_I PF00867.13 ABX12599.1 - 9e-23 80.1 0.0 2.2e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 ABX12599.1 - 7.4e-22 77.5 0.0 4.3e-21 75.0 0.0 2.0 1 1 1 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 ABX12599.1 - 0.0002 21.5 0.0 0.00056 20.1 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold BRF1 PF07741.8 ABX12599.1 - 0.14 12.4 0.2 0.14 12.4 0.1 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain TrmB PF01978.14 ABX12601.1 - 6.2e-14 51.4 0.0 1.4e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_9 PF08221.6 ABX12601.1 - 0.00013 21.7 0.2 0.00092 19.0 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain z-alpha PF02295.12 ABX12601.1 - 0.0013 18.4 0.0 0.016 14.9 0.0 2.4 2 0 0 2 2 2 1 Adenosine deaminase z-alpha domain HTH_IclR PF09339.5 ABX12601.1 - 0.002 17.6 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain Rrf2 PF02082.15 ABX12601.1 - 0.044 13.8 0.0 0.19 11.8 0.0 2.1 1 0 0 1 1 1 0 Transcriptional regulator DUF2250 PF10007.4 ABX12601.1 - 0.063 13.1 0.5 0.26 11.2 0.0 2.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_20 PF12840.2 ABX12601.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Med12 PF09497.5 ABX12601.1 - 0.12 12.3 0.7 4.1 7.4 0.0 2.8 2 1 1 3 3 3 0 Transcription mediator complex subunit Med12 Peptidase_M10 PF00413.19 ABX12602.1 - 1.2e-08 34.8 0.1 5e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 ABX12602.1 - 0.0012 18.2 1.3 0.0012 18.1 0.0 1.6 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.4 ABX12602.1 - 0.013 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.1 ABX12602.1 - 0.032 13.7 0.6 0.051 13.1 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 ABX12602.1 - 0.059 13.4 2.0 0.075 13.0 0.1 2.2 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 ABX12602.1 - 0.063 13.8 0.7 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 ABX12602.1 - 0.14 12.0 0.6 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12 Response_reg PF00072.19 ABX12603.1 - 2.4e-14 53.3 0.1 4.3e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain DUF3227 PF11537.3 ABX12603.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3227) B2-adapt-app_C PF09066.5 ABX12603.1 - 0.013 15.4 0.0 0.064 13.1 0.0 2.0 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain RFC1 PF08519.7 ABX12603.1 - 0.084 12.6 0.3 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain EST1_DNA_bind PF10373.4 ABX12604.1 - 0.092 11.9 0.4 0.091 11.9 0.3 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Nitroreductase PF00881.19 ABX12605.1 - 1.7e-30 106.0 0.0 2.2e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family AsnC_trans_reg PF01037.16 ABX12606.1 - 2.6e-10 39.8 0.2 3.1e-10 39.6 0.1 1.0 1 0 0 1 1 1 1 AsnC family DUF1057 PF06342.7 ABX12606.1 - 0.051 12.3 0.3 0.052 12.3 0.2 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Orbi_VP5 PF00901.12 ABX12606.1 - 0.084 11.0 1.0 0.1 10.7 0.7 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF1206 PF06724.6 ABX12608.1 - 0.14 11.9 4.0 0.25 11.1 0.4 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) Polyketide_cyc2 PF10604.4 ABX12609.1 - 1.3e-14 54.5 0.0 1.5e-14 54.3 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 ABX12609.1 - 0.045 13.7 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport COX6A PF02046.10 ABX12609.1 - 0.1 12.5 0.2 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa APG6 PF04111.7 ABX12610.1 - 0.00042 19.4 18.3 0.00042 19.4 12.7 2.8 3 0 0 3 3 3 2 Autophagy protein Apg6 DUF4349 PF14257.1 ABX12610.1 - 0.00079 18.7 1.8 0.0096 15.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4349) Fib_alpha PF08702.5 ABX12610.1 - 0.01 15.9 4.0 0.01 15.9 2.8 4.1 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 ABX12610.1 - 0.07 12.9 30.9 0.036 13.8 1.2 5.1 2 1 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.16 ABX12610.1 - 0.45 10.0 25.7 0.029 13.8 2.2 3.5 2 2 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Reo_sigmaC PF04582.7 ABX12610.1 - 0.58 9.2 28.3 0.69 9.0 5.3 3.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Flagellin_N PF00669.15 ABX12610.1 - 0.78 9.5 16.3 0.19 11.5 3.8 3.4 3 1 0 3 3 3 0 Bacterial flagellin N-terminal helical region AAA_13 PF13166.1 ABX12610.1 - 1.7 7.0 45.9 0.02 13.4 14.4 2.4 1 1 2 3 3 3 0 AAA domain HD_3 PF13023.1 ABX12610.1 - 2.4 7.8 9.6 0.45 10.2 1.1 3.0 1 1 2 3 3 3 0 HD domain Endotoxin_N PF03945.9 ABX12610.1 - 4.5 6.6 20.8 0.062 12.6 1.0 3.3 2 1 2 4 4 4 0 delta endotoxin, N-terminal domain Prok-JAB PF14464.1 ABX12611.1 - 4.1e-12 45.6 0.0 5.2e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.16 ABX12611.1 - 0.00067 19.3 0.1 0.0053 16.4 0.1 2.0 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RadC PF04002.10 ABX12611.1 - 0.018 14.7 0.2 0.02 14.5 0.2 1.3 1 1 0 1 1 1 0 RadC-like JAB domain zf-NADH-PPase PF09297.6 ABX12612.1 - 0.025 14.0 4.0 0.03 13.8 0.5 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Peptidase_C74 PF12387.3 ABX12612.1 - 0.063 12.4 1.3 0.087 11.9 0.9 1.1 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Zn_ribbon_recom PF13408.1 ABX12612.1 - 0.34 11.1 4.8 2.9 8.2 3.3 2.1 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain TF_Zn_Ribbon PF08271.7 ABX12612.1 - 0.35 10.2 1.9 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding Opy2 PF09463.5 ABX12612.1 - 0.42 10.7 2.2 0.55 10.3 1.5 1.1 1 0 0 1 1 1 0 Opy2 protein Zn-ribbon_8 PF09723.5 ABX12612.1 - 0.86 9.6 3.9 4.1 7.4 2.7 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zf-HIT PF04438.11 ABX12612.1 - 1.7 8.3 5.0 3 7.5 3.5 1.4 1 1 0 1 1 1 0 HIT zinc finger TFIIS_C PF01096.13 ABX12612.1 - 3 7.5 4.9 16 5.1 0.3 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) P12 PF12669.2 ABX12612.1 - 6.8 6.9 10.1 8.7e+02 0.2 7.0 2.2 1 1 0 1 1 1 0 Virus attachment protein p12 family SAG PF04092.8 ABX12613.1 - 0.0007 19.9 0.2 0.00081 19.7 0.2 1.1 1 0 0 1 1 1 1 SRS domain SH2_2 PF14633.1 ABX12613.1 - 0.017 14.2 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 SH2 domain Spherulin4 PF12138.3 ABX12613.1 - 0.066 12.6 0.3 0.074 12.4 0.2 1.1 1 0 0 1 1 1 0 Spherulation-specific family 4 BPD_transp_1 PF00528.17 ABX12614.1 - 5.3e-25 88.0 9.2 5.3e-25 88.0 6.4 2.1 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.2 ABX12614.1 - 0.003 16.9 0.0 0.013 14.8 0.0 2.1 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.17 ABX12615.1 - 2.3e-38 131.5 17.9 2.3e-38 131.5 12.4 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.16 ABX12615.1 - 1.7 8.4 31.6 0.3 10.8 6.5 3.3 3 1 0 3 3 3 0 FtsX-like permease family DUF2332 PF10094.4 ABX12616.1 - 0.044 12.7 0.0 0.047 12.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) S4 PF01479.20 ABX12617.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 S4 domain SWIM PF04434.12 ABX12617.1 - 0.84 9.1 3.0 2.2 7.8 2.1 1.7 1 1 0 1 1 1 0 SWIM zinc finger ArsC PF03960.10 ABX12618.1 - 7.1e-19 67.9 0.7 8.1e-19 67.7 0.5 1.0 1 0 0 1 1 1 1 ArsC family CarboxypepD_reg PF13620.1 ABX12619.1 - 9.2e-07 28.8 0.4 2.3e-06 27.5 0.3 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 ABX12619.1 - 0.00042 20.3 0.1 0.0009 19.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Dioxygenase_C PF00775.16 ABX12619.1 - 0.024 13.9 0.0 0.06 12.5 0.0 1.6 1 0 0 1 1 1 0 Dioxygenase DUF3901 PF13040.1 ABX12619.1 - 0.51 9.6 4.1 1.2 8.4 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3901) PAC2 PF09754.4 ABX12621.1 - 1.6e-17 64.1 0.0 1.9e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 PAC2 family SNF2_N PF00176.18 ABX12622.1 - 3.1e-40 137.8 0.2 4.9e-40 137.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ABX12622.1 - 1.4e-08 34.4 0.0 4.3e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ABX12622.1 - 5.8e-08 32.4 0.1 2e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 ABX12622.1 - 1.7e-06 27.9 5.2 2e-06 27.7 0.0 2.8 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit PTPlike_phytase PF14566.1 ABX12622.1 - 0.049 13.6 1.2 0.15 12.1 0.9 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate ATP-synt_ab_C PF00306.22 ABX12623.1 - 0.039 14.4 2.1 0.095 13.1 1.4 1.8 1 1 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain HTH_5 PF01022.15 ABX12623.1 - 0.079 12.6 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF1492 PF07374.6 ABX12623.1 - 0.27 11.3 2.4 0.88 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) TFIIE_alpha PF02002.12 ABX12623.1 - 0.55 9.7 6.4 0.32 10.5 0.2 2.5 3 0 0 3 3 3 0 TFIIE alpha subunit DUF148 PF02520.12 ABX12624.1 - 0.36 10.6 7.8 0.049 13.4 1.9 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF148 V_ATPase_I PF01496.14 ABX12624.1 - 0.4 8.4 10.2 0.34 8.7 6.1 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Sod_Fe_C PF02777.13 ABX12625.1 - 3.2e-41 139.4 1.0 3.2e-41 139.4 0.7 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 ABX12625.1 - 2.6e-24 85.2 0.1 5.5e-24 84.2 0.1 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Mad3_BUB1_II PF08171.6 ABX12627.1 - 0.027 14.3 0.3 0.057 13.3 0.1 1.6 2 0 0 2 2 2 0 Mad3/BUB1 homology region 2 GFA PF04828.9 ABX12629.1 - 0.19 11.6 1.9 0.95 9.4 1.4 1.8 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Ornatin PF02088.10 ABX12629.1 - 0.28 10.7 3.2 0.45 10.1 2.2 1.5 1 1 0 1 1 1 0 Ornatin zf-C3HC4_3 PF13920.1 ABX12629.1 - 0.35 10.5 3.1 1.1 8.9 2.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FAD-oxidase_C PF02913.14 ABX12630.1 - 1.4e-41 142.4 0.0 1.7e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ABX12630.1 - 1.9e-31 108.4 0.0 3.3e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ABX12630.1 - 0.0011 18.8 0.0 0.0027 17.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 ABX12630.1 - 0.007 15.5 0.4 0.028 13.5 0.0 2.0 2 0 0 2 2 2 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF4113 PF13438.1 ABX12630.1 - 0.14 11.7 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) HD PF01966.17 ABX12631.1 - 0.0067 16.4 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 HD domain Acetyltransf_1 PF00583.19 ABX12631.1 - 0.092 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PDEase_I PF00233.14 ABX12631.1 - 0.1 12.3 4.8 0.11 12.1 0.5 2.6 2 1 1 3 3 3 0 3'5'-cyclic nucleotide phosphodiesterase DnaJ PF00226.26 ABX12633.1 - 8.7e-24 83.0 3.1 8.7e-24 83.0 2.1 1.8 2 0 0 2 2 2 1 DnaJ domain RyR PF02026.11 ABX12633.1 - 0.89 9.6 4.3 0.55 10.2 0.7 2.1 1 1 1 2 2 2 0 RyR domain HTH_AsnC-type PF13404.1 ABX12634.1 - 5.2e-13 48.3 1.0 9.2e-13 47.5 0.7 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 ABX12634.1 - 6.7e-13 47.8 2.2 3.3e-12 45.5 1.1 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.16 ABX12634.1 - 1e-12 47.5 0.2 1.6e-12 46.9 0.2 1.4 1 0 0 1 1 1 1 AsnC family HTH_11 PF08279.7 ABX12634.1 - 0.0001 21.8 1.5 0.0002 20.9 0.5 1.9 1 1 1 2 2 2 1 HTH domain HTH_Crp_2 PF13545.1 ABX12634.1 - 0.00069 19.3 0.1 0.0016 18.1 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_20 PF12840.2 ABX12634.1 - 0.0088 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DDRGK PF09756.4 ABX12634.1 - 0.01 15.2 1.2 0.046 13.1 0.8 1.9 1 1 0 1 1 1 0 DDRGK domain HTH_10 PF04967.7 ABX12634.1 - 0.021 14.4 0.3 0.053 13.1 0.1 1.8 2 0 0 2 2 2 0 HTH DNA binding domain HTH_38 PF13936.1 ABX12634.1 - 0.022 14.2 0.1 0.24 10.9 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.2 ABX12634.1 - 0.036 13.7 0.0 0.076 12.6 0.0 1.6 1 0 0 1 1 1 0 MarR family MarR PF01047.17 ABX12634.1 - 0.037 13.7 0.2 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 MarR family DUF711 PF05167.7 ABX12634.1 - 0.06 12.0 1.0 0.11 11.1 0.7 1.5 1 1 0 1 1 1 0 Uncharacterised ACR (DUF711) GYD PF08734.6 ABX12634.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 GYD domain DUF603 PF04645.7 ABX12634.1 - 0.19 11.6 2.3 1.8 8.4 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function, DUF603 HTH_3 PF01381.17 ABX12634.1 - 0.24 11.2 1.1 0.79 9.6 0.1 2.5 4 1 0 4 4 4 0 Helix-turn-helix TPR_1 PF00515.23 ABX12635.1 - 6.6e-17 60.3 0.1 1.2e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ABX12635.1 - 7.9e-16 56.6 0.1 4e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 ABX12635.1 - 9.7e-16 57.1 0.0 1.1e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 ABX12635.1 - 2.8e-10 39.2 0.1 1.2e-07 31.0 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ABX12635.1 - 1.5e-09 38.2 0.0 1.9e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 ABX12635.1 - 3e-09 37.0 0.0 3.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 ABX12635.1 - 5.4e-09 35.1 0.0 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ABX12635.1 - 7.2e-09 35.5 0.1 0.0028 18.1 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ABX12635.1 - 1e-08 34.9 0.0 5.7e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 ABX12635.1 - 1.2e-08 34.4 0.8 4.2e-06 26.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 ABX12635.1 - 4.2e-08 32.9 0.0 5.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 ABX12635.1 - 6.1e-05 22.8 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat NARP1 PF12569.3 ABX12635.1 - 0.00092 18.0 0.0 0.001 17.9 0.0 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Apc3 PF12895.2 ABX12635.1 - 0.00097 19.2 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 ABX12635.1 - 0.0037 17.1 0.4 2.1 8.5 0.0 2.3 2 0 0 2 2 2 2 PPR repeat TPR_3 PF07720.7 ABX12635.1 - 0.005 16.6 0.0 0.54 10.1 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.2 ABX12635.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 ABX12635.1 - 0.023 15.1 0.0 4.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ABX12635.1 - 0.041 13.7 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 ABX12635.1 - 0.1 13.0 0.0 12 6.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 ABX12635.1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.8 1 1 0 1 1 1 0 Tetratrico peptide repeat TPR_11 PF13414.1 ABX12636.1 - 1.2e-26 92.1 1.9 7.3e-13 47.9 0.9 2.5 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ABX12636.1 - 6.7e-25 85.6 3.4 3.7e-07 29.4 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ABX12636.1 - 7.3e-21 72.3 1.3 4.3e-05 23.1 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 ABX12636.1 - 2.7e-18 66.1 0.0 9.6e-07 29.3 0.0 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 ABX12636.1 - 8.5e-16 57.6 1.5 6.1e-09 35.6 0.7 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ABX12636.1 - 3.6e-13 48.2 2.9 0.0034 17.0 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ABX12636.1 - 1.3e-12 47.1 0.1 0.028 15.0 0.0 4.1 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 ABX12636.1 - 2e-12 45.8 0.6 0.0092 15.7 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ABX12636.1 - 6e-12 44.7 1.1 4.8e-05 23.2 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ABX12636.1 - 6.1e-12 45.6 1.6 3.4e-05 24.1 0.5 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 ABX12636.1 - 1.1e-10 41.5 4.4 7.8e-06 25.9 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ABX12636.1 - 2.8e-08 33.5 0.0 0.00011 21.9 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ABX12636.1 - 4e-08 33.1 1.5 0.034 14.5 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 ABX12636.1 - 2.6e-07 30.4 3.2 0.13 12.1 0.0 4.1 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 ABX12636.1 - 6.6e-06 25.8 0.0 0.2 11.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.2 ABX12636.1 - 0.00025 20.8 0.1 2.8 7.7 0.0 3.3 1 1 2 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_3 PF07720.7 ABX12636.1 - 0.00031 20.4 1.5 4 7.3 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 ABX12636.1 - 0.0042 17.1 1.6 0.12 12.5 0.2 2.5 1 1 2 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ABX12636.1 - 0.0048 16.7 1.7 2.9 7.8 0.0 3.9 4 1 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.3 ABX12636.1 - 0.009 14.8 0.7 1.3 7.6 0.0 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 DUF627 PF04781.7 ABX12636.1 - 0.015 14.9 0.7 1.7 8.2 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF627) PPR PF01535.15 ABX12636.1 - 0.018 14.9 0.2 27 5.0 0.0 3.7 4 0 0 4 4 3 0 PPR repeat MerR_2 PF13591.1 ABX12636.1 - 0.13 11.8 0.1 0.33 10.5 0.1 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein zf-C2H2_4 PF13894.1 ABX12637.1 - 0.0025 18.0 1.7 0.0027 17.9 0.6 1.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 ABX12637.1 - 0.0045 17.2 2.0 0.0053 17.0 0.9 1.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 ABX12637.1 - 0.0058 16.7 1.2 0.0065 16.5 0.9 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.9 ABX12637.1 - 0.018 14.4 2.4 0.029 13.8 1.4 1.5 1 1 0 1 1 1 0 Rad50 zinc hook motif DUF808 PF05661.7 ABX12637.1 - 0.053 12.3 0.2 0.058 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF808) OTT_1508_deam PF14441.1 ABX12637.1 - 0.079 12.7 0.1 0.092 12.5 0.1 1.1 1 0 0 1 1 1 0 OTT_1508-like deaminase zf-C2H2_jaz PF12171.3 ABX12637.1 - 0.095 12.8 2.8 0.17 12.0 0.4 2.0 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding Radical_SAM PF04055.16 ABX12638.1 - 7.4e-16 58.7 0.1 1.9e-15 57.4 0.0 1.7 1 1 1 2 2 2 1 Radical SAM superfamily ATP-sulfurylase PF01747.12 ABX12638.1 - 0.0062 15.8 0.1 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase DUF77 PF01910.12 ABX12639.1 - 1.8e-25 88.4 1.8 2e-25 88.2 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Rnf-Nqr PF02508.9 ABX12640.1 - 0.0027 17.3 0.0 0.0034 17.0 0.0 1.1 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein DUF4345 PF14248.1 ABX12640.1 - 0.064 12.7 0.1 0.075 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) Tetraspannin PF00335.15 ABX12640.1 - 0.13 11.4 0.2 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Tetraspanin family AlaDh_PNT_C PF01262.16 ABX12641.1 - 0.12 11.9 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain VitK2_biosynth PF02621.9 ABX12642.1 - 5.1e-72 242.0 0.0 5.8e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis SIS PF01380.17 ABX12643.1 - 3.1e-06 26.8 1.9 0.037 13.6 0.5 2.7 2 1 0 2 2 2 2 SIS domain DUF1077 PF06417.7 ABX12643.1 - 0.068 12.5 0.2 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) GTP_EFTU PF00009.22 ABX12644.1 - 5.4e-57 192.2 0.7 8.9e-57 191.5 0.5 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 ABX12644.1 - 4e-27 94.1 0.0 1.8e-26 92.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 ABX12644.1 - 3.1e-21 74.9 0.6 6.9e-21 73.8 0.4 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 ABX12644.1 - 9.9e-20 70.2 0.0 3.9e-19 68.3 0.0 2.2 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 ABX12644.1 - 2.9e-14 52.9 0.1 9.8e-14 51.2 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF2666 PF10869.3 ABX12647.1 - 0.072 13.1 0.4 0.085 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Erp_C PF06780.6 ABX12648.1 - 0.0022 17.8 1.4 0.18 11.6 0.0 2.2 1 1 0 2 2 2 2 Erp protein C-terminus DUF2443 PF10398.4 ABX12648.1 - 0.067 12.9 1.5 0.13 12.0 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Baculo_PEP_C PF04513.7 ABX12648.1 - 0.086 12.6 1.0 0.2 11.4 0.7 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MSA-2c PF12238.3 ABX12648.1 - 0.09 12.4 2.8 2 8.0 1.8 2.0 1 1 1 2 2 2 0 Merozoite surface antigen 2c DAP_B PF07930.7 ABX12648.1 - 0.09 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 D-aminopeptidase, domain B Syntaxin_2 PF14523.1 ABX12648.1 - 0.091 12.7 1.1 0.19 11.8 0.3 1.9 1 1 1 2 2 2 0 Syntaxin-like protein Uteroglobin PF01099.12 ABX12648.1 - 0.42 10.4 1.9 0.31 10.8 0.1 1.6 2 0 0 2 2 2 0 Uteroglobin family TauE PF01925.14 ABX12649.1 - 0.035 13.5 4.3 0.046 13.1 2.9 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE PepSY_TM_3 PF13706.1 ABX12649.1 - 0.86 9.0 5.0 3.8 6.9 0.5 2.5 2 1 1 3 3 3 0 PepSY-associated TM helix Methyltransf_3 PF01596.12 ABX12651.1 - 2.1e-36 124.9 1.0 2.4e-36 124.7 0.7 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 ABX12651.1 - 7.2e-14 52.5 0.0 1.1e-13 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX12651.1 - 1.3e-09 38.5 0.0 1.9e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ABX12651.1 - 9.8e-08 31.7 0.6 1.3e-07 31.3 0.4 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ABX12651.1 - 4.5e-07 29.6 1.1 4.6e-07 29.5 0.1 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CmcI PF04989.7 ABX12651.1 - 5e-06 25.9 0.7 6.5e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_26 PF13659.1 ABX12651.1 - 4.6e-05 23.4 0.0 5.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ABX12651.1 - 0.00075 18.6 0.5 0.075 12.0 0.4 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.7 ABX12651.1 - 0.0089 16.4 0.0 0.024 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 ABX12651.1 - 0.01 15.2 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GCD14 PF08704.5 ABX12651.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit UPF0020 PF01170.13 ABX12651.1 - 0.015 14.8 0.8 0.032 13.8 0.3 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Chordopox_A30L PF06015.7 ABX12651.1 - 0.02 14.4 1.3 0.02 14.4 0.9 2.3 3 1 0 3 3 3 0 Chordopoxvirus A30L protein Methyltransf_15 PF09445.5 ABX12651.1 - 0.036 13.6 0.2 0.054 13.0 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF1442 PF07279.6 ABX12651.1 - 0.038 13.0 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) Cons_hypoth95 PF03602.10 ABX12651.1 - 0.05 12.9 1.4 0.063 12.6 0.3 1.7 1 1 1 2 2 2 0 Conserved hypothetical protein 95 Sulphotransf PF09037.5 ABX12652.1 - 0.09 12.2 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Stf0 sulphotransferase AvrL567-A PF11529.3 ABX12652.1 - 0.092 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A Toxin_10 PF05431.6 ABX12652.1 - 0.096 12.3 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 DUF1911 PF08929.5 ABX12654.1 - 0.046 14.4 0.7 0.049 14.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) CUE PF02845.11 ABX12654.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 CUE domain DUF2680 PF10925.3 ABX12654.1 - 0.09 12.6 0.9 0.18 11.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) DUF4164 PF13747.1 ABX12654.1 - 0.1 12.7 2.0 0.15 12.2 1.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) 4HB_MCP_1 PF12729.2 ABX12654.1 - 0.11 11.7 3.1 0.12 11.7 2.2 1.0 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Cas_Cmr5 PF09701.5 ABX12654.1 - 0.22 11.6 2.0 0.27 11.4 1.4 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) U1snRNP70_N PF12220.3 ABX12654.1 - 0.54 10.6 3.5 0.65 10.3 2.5 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Mut7-C PF01927.11 ABX12655.1 - 4.4e-07 29.9 0.1 4.7e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain Fcf1 PF04900.7 ABX12655.1 - 0.0015 18.5 0.0 0.0016 18.4 0.0 1.1 1 0 0 1 1 1 1 Fcf1 DUF4411 PF14367.1 ABX12655.1 - 0.029 14.0 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) UPF0180 PF03698.8 ABX12655.1 - 0.034 13.9 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) PIN PF01850.16 ABX12655.1 - 0.059 13.6 0.0 0.1 12.9 0.0 1.5 1 1 0 1 1 1 0 PIN domain DUF562 PF04763.7 ABX12655.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF562) HTH_24 PF13412.1 ABX12656.1 - 0.0021 17.4 0.9 0.0099 15.2 0.3 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 ABX12656.1 - 0.0037 16.8 0.3 0.017 14.7 0.2 2.1 1 1 0 1 1 1 1 HTH domain EcoR124_C PF12008.3 ABX12656.1 - 0.0051 16.0 0.2 0.011 14.9 0.2 1.5 1 0 0 1 1 1 1 Type I restriction and modification enzyme - subunit R C terminal Syntaxin-6_N PF09177.6 ABX12656.1 - 0.0072 16.7 1.7 0.013 15.9 1.1 1.5 1 1 0 1 1 1 1 Syntaxin 6, N-terminal MitMem_reg PF13012.1 ABX12656.1 - 0.037 14.1 1.2 0.047 13.7 0.3 1.7 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function HTH_AsnC-type PF13404.1 ABX12656.1 - 0.054 13.0 0.1 0.054 13.0 0.1 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DASH_Dad3 PF08656.5 ABX12656.1 - 0.062 12.9 0.6 0.2 11.3 0.3 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 Baculo_PEP_C PF04513.7 ABX12656.1 - 0.068 12.9 0.3 0.13 12.0 0.1 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.15 ABX12656.1 - 0.097 12.4 1.4 2 8.2 0.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit PIN_3 PF13470.1 ABX12656.1 - 0.13 12.9 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 PIN domain DUF3878 PF12994.2 ABX12657.1 - 0.027 13.6 0.1 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) DUF1132 PF06575.7 ABX12657.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1132) Fis1_TPR_N PF14852.1 ABX12657.1 - 0.066 12.5 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat HisK_N PF09385.5 ABX12658.1 - 0.058 13.0 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase N terminal DUF1360 PF07098.6 ABX12659.1 - 0.019 14.7 0.3 0.083 12.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1360) KRTAP7 PF15034.1 ABX12659.1 - 0.062 13.9 0.5 0.11 13.0 0.3 1.4 1 0 0 1 1 1 0 KRTAP type 7 family TrkH PF02386.11 ABX12660.1 - 2.8e-26 91.9 35.7 7.2e-24 84.0 15.9 3.4 1 1 1 2 2 2 2 Cation transport protein CBS PF00571.23 ABX12660.1 - 5e-20 71.0 3.8 6.7e-12 45.0 0.1 2.4 2 0 0 2 2 2 2 CBS domain La PF05383.12 ABX12660.1 - 0.085 12.6 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 La domain DUF843 PF05814.6 ABX12660.1 - 6.9 6.5 7.9 14 5.5 0.5 3.3 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) DNase-RNase PF02577.9 ABX12661.1 - 4.6e-08 32.3 0.0 4.9e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease YgaB PF14182.1 ABX12662.1 - 0.33 11.2 2.2 0.45 10.7 1.5 1.2 1 0 0 1 1 1 0 YgaB-like protein BatD PF13584.1 ABX12663.1 - 0.019 13.5 0.0 0.022 13.3 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance Lar_restr_allev PF14354.1 ABX12665.1 - 0.0018 18.5 0.0 0.0022 18.2 0.0 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar DUF2387 PF09526.5 ABX12665.1 - 0.014 15.3 0.3 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) zinc_ribbon_5 PF13719.1 ABX12665.1 - 0.023 14.2 0.4 0.052 13.1 0.3 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-FPG_IleRS PF06827.9 ABX12665.1 - 0.035 13.7 0.4 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zinc_ribbon_4 PF13717.1 ABX12665.1 - 0.046 13.4 0.8 0.1 12.2 0.5 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-DNA_Pol PF08996.5 ABX12665.1 - 0.056 12.7 0.2 0.072 12.4 0.2 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-trcl PF13451.1 ABX12665.1 - 0.074 12.6 0.2 2.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain TF_Zn_Ribbon PF08271.7 ABX12665.1 - 0.19 11.1 1.2 0.36 10.1 0.8 1.4 1 1 0 1 1 1 0 TFIIB zinc-binding DZR PF12773.2 ABX12665.1 - 0.23 11.2 1.4 0.47 10.3 1.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon Gin PF10764.4 ABX12665.1 - 0.25 11.0 3.9 2.2 8.0 0.2 2.4 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin DUF4182 PF13790.1 ABX12665.1 - 3.3 7.5 5.1 0.91 9.3 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) DUF1297 PF06973.7 ABX12666.1 - 6.5e-74 247.3 0.1 9.6e-74 246.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.7 ABX12666.1 - 5.1e-48 161.9 0.0 1.2e-47 160.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) Flavoprotein PF02441.14 ABX12667.1 - 2.9e-30 104.5 0.5 3.9e-30 104.1 0.4 1.1 1 0 0 1 1 1 1 Flavoprotein DUF2888 PF11135.3 ABX12667.1 - 0.02 14.6 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) Polyketide_cyc PF03364.15 ABX12668.1 - 9.6e-07 28.8 0.0 1.3e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 ABX12668.1 - 0.0044 17.1 0.0 0.0054 16.8 0.0 1.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MttA_Hcf106 PF02416.11 ABX12669.1 - 4.1e-10 38.6 4.7 5.7e-10 38.1 3.3 1.3 1 1 0 1 1 1 1 mttA/Hcf106 family TrbC PF04956.8 ABX12669.1 - 0.13 12.2 1.1 0.16 11.9 0.8 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family GnsAB PF08178.6 ABX12669.1 - 0.14 11.8 1.5 0.45 10.2 0.9 1.9 2 1 0 2 2 2 0 GnsA/GnsB family YtpI PF14007.1 ABX12669.1 - 0.14 12.0 0.7 0.17 11.8 0.5 1.2 1 0 0 1 1 1 0 YtpI-like protein TatC PF00902.13 ABX12670.1 - 3.1e-61 206.4 14.3 3.7e-61 206.2 9.9 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) Orbi_NS3 PF01616.11 ABX12670.1 - 0.15 10.9 0.3 10 4.9 0.0 2.7 3 0 0 3 3 3 0 Orbivirus NS3 LrgA PF03788.9 ABX12670.1 - 0.87 9.3 10.4 0.62 9.7 0.1 3.4 2 2 2 4 4 4 0 LrgA family 2TM PF13239.1 ABX12670.1 - 1.4 9.0 6.2 0.78 9.8 0.1 3.2 4 0 0 4 4 4 0 2TM domain Peptidase_C11 PF03415.9 ABX12671.1 - 0.037 13.0 0.9 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 Clostripain family SmpA_OmlA PF04355.8 ABX12672.1 - 0.04 13.5 0.1 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 SmpA / OmlA family PurS PF02700.9 ABX12673.1 - 2.7e-21 75.2 0.4 3e-21 75.1 0.3 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase CBS PF00571.23 ABX12674.1 - 3.3e-31 106.7 0.5 3.5e-15 55.5 0.0 2.1 2 0 0 2 2 2 2 CBS domain GATase_5 PF13507.1 ABX12675.1 - 1.5e-42 145.3 0.0 4.5e-42 143.7 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.9 ABX12675.1 - 2.7e-09 36.8 0.0 2e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 ABX12675.1 - 1.3e-08 34.5 0.0 2e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 ABX12675.1 - 3.4e-06 26.5 0.0 5.3e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 ABX12675.1 - 1.7e-05 24.1 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_C26 PF07722.8 ABX12675.1 - 0.0028 17.1 0.1 0.011 15.2 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.14 ABX12675.1 - 0.019 14.5 0.0 0.048 13.2 0.0 1.6 2 0 0 2 2 2 0 SNO glutamine amidotransferase family AIRS_C PF02769.17 ABX12676.1 - 2.2e-47 160.8 0.2 6.9e-25 87.8 0.3 2.2 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 ABX12676.1 - 2.5e-39 133.4 0.1 7.3e-22 77.4 0.2 2.5 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain GATase_2 PF00310.16 ABX12677.1 - 1.1e-20 73.6 0.0 1.7e-14 53.3 0.0 3.2 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 ABX12677.1 - 5.5e-18 65.2 0.0 1.5e-16 60.6 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 ABX12677.1 - 4.3e-14 52.3 0.0 1.3e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 ABX12677.1 - 5.6e-14 51.9 0.2 1.7e-13 50.3 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 ABX12677.1 - 8.5e-06 24.6 0.0 1.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pribosyltran_N PF13793.1 ABX12677.1 - 0.09 12.5 0.1 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase DUF427 PF04248.7 ABX12678.1 - 3.2e-29 100.4 0.5 3.8e-29 100.1 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) DAHP_synth_1 PF00793.15 ABX12678.1 - 0.075 11.7 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 DAHP synthetase I family SAICAR_synt PF01259.13 ABX12680.1 - 3e-70 236.1 0.3 3.7e-70 235.8 0.2 1.1 1 0 0 1 1 1 1 SAICAR synthetase HTH_20 PF12840.2 ABX12681.1 - 1e-09 38.0 0.2 1.6e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.15 ABX12681.1 - 9.9e-07 28.3 0.5 9e-06 25.2 0.4 2.2 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family FUR PF01475.14 ABX12681.1 - 0.00013 21.8 0.6 0.00029 20.7 0.4 1.7 1 1 0 1 1 1 1 Ferric uptake regulator family HTH_12 PF08461.5 ABX12681.1 - 0.00029 20.5 0.3 0.00058 19.5 0.2 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Replic_Relax PF13814.1 ABX12681.1 - 0.06 13.1 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Replication-relaxation ArgK PF03308.11 ABX12681.1 - 0.063 12.0 0.5 0.5 9.0 0.0 2.1 2 0 0 2 2 2 0 ArgK protein DUF1933 PF09147.5 ABX12681.1 - 0.09 12.1 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) HTH_11 PF08279.7 ABX12681.1 - 0.11 12.1 1.1 0.68 9.6 0.8 2.1 1 1 0 1 1 1 0 HTH domain Gly_acyl_tr_N PF06021.6 ABX12682.1 - 0.026 13.9 1.4 0.028 13.8 0.9 1.2 1 1 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Pyridox_oxidase PF01243.15 ABX12683.1 - 2.3e-15 56.3 0.0 3.4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 ABX12683.1 - 0.0038 17.0 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4352 PF11611.3 ABX12685.1 - 7.1e-09 35.8 0.2 9.1e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) DUF2299 PF10061.4 ABX12687.1 - 7.3e-08 31.9 0.1 8.7e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2299) TMEM223 PF14640.1 ABX12687.1 - 0.088 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 DZR PF12773.2 ABX12688.1 - 0.041 13.6 0.2 0.063 13.0 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-IS66 PF13005.2 ABX12688.1 - 0.13 12.3 1.3 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 C1_4 PF07975.7 ABX12688.1 - 0.15 12.0 2.2 8.5 6.4 2.2 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zf-LYAR PF08790.6 ABX12688.1 - 0.25 11.0 3.3 8.1 6.2 0.3 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Ribosomal_L6 PF00347.18 ABX12690.1 - 3.8e-15 56.1 5.0 2.9e-07 30.8 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 S_layer_C PF05124.7 ABX12690.1 - 0.0068 16.0 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 S-layer like family, C-terminal region Ribosomal_S8 PF00410.14 ABX12691.1 - 8.2e-23 80.6 0.0 1e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S14 PF00253.16 ABX12692.1 - 4.3e-15 54.8 5.0 5.2e-15 54.5 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-FPG_IleRS PF06827.9 ABX12692.1 - 0.022 14.3 2.2 0.048 13.3 1.3 1.6 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS DUF2318 PF10080.4 ABX12692.1 - 0.11 12.2 0.2 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-AD PF07776.10 ABX12692.1 - 0.3 11.0 1.6 1 9.4 1.4 1.7 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) Ribosomal_L5_C PF00673.16 ABX12693.1 - 5.8e-22 77.2 0.0 1e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 ABX12693.1 - 9e-12 44.6 0.0 1.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Toxin_55 PF15606.1 ABX12693.1 - 0.068 13.1 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Putative toxin 55 Ribosomal_S4e PF00900.15 ABX12694.1 - 3.8e-22 77.7 0.9 7e-22 76.8 0.6 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 ABX12694.1 - 9.8e-14 50.9 4.0 1.7e-13 50.1 2.8 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 ABX12694.1 - 0.00026 20.3 0.3 0.00081 18.7 0.0 2.0 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 ABX12694.1 - 0.00028 20.4 0.1 0.0014 18.2 0.0 2.4 2 0 0 2 2 2 1 KOW motif KOW PF00467.24 ABX12695.1 - 3.9e-05 23.1 1.5 8.8e-05 22.0 1.0 1.7 1 0 0 1 1 1 1 KOW motif Methyltrans_RNA PF04452.9 ABX12695.1 - 0.035 13.2 0.4 0.075 12.1 0.1 1.8 1 1 1 2 2 2 0 RNA methyltransferase RR_TM4-6 PF06459.7 ABX12695.1 - 8.3 6.2 13.7 9.1 6.0 9.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_L14 PF00238.14 ABX12696.1 - 4.8e-33 113.5 0.1 5.4e-33 113.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_S17 PF00366.15 ABX12697.1 - 2.4e-17 62.6 0.4 3.6e-17 62.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 UPF0086 PF01868.11 ABX12698.1 - 2.5e-27 94.3 0.1 2.7e-27 94.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_L29 PF00831.18 ABX12699.1 - 3.1e-15 55.5 4.0 3.6e-15 55.3 2.8 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein EzrA PF06160.7 ABX12699.1 - 0.039 12.1 0.6 0.041 12.0 0.4 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Snapin_Pallidin PF14712.1 ABX12699.1 - 0.18 12.1 2.0 0.23 11.7 1.4 1.2 1 0 0 1 1 1 0 Snapin/Pallidin Ribosomal_S3_C PF00189.15 ABX12700.1 - 2e-13 50.3 0.2 5.1e-13 49.0 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 ABX12700.1 - 1.2e-12 47.1 0.0 1.2e-12 47.1 0.0 2.5 3 0 0 3 3 3 1 KH domain KH_1 PF00013.24 ABX12700.1 - 0.03 13.9 1.4 0.12 12.0 0.1 2.6 3 0 0 3 3 3 0 KH domain KH_3 PF13014.1 ABX12700.1 - 0.12 12.0 1.0 0.36 10.5 0.3 2.1 2 0 0 2 2 2 0 KH domain Ribosomal_L22 PF00237.14 ABX12701.1 - 5.7e-31 106.5 1.2 6.8e-31 106.3 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S19 PF00203.16 ABX12702.1 - 1.9e-23 81.8 0.3 2.7e-23 81.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L23 PF00276.15 ABX12703.1 - 1.1e-12 47.6 1.8 2.7e-12 46.4 1.2 1.6 1 1 0 1 1 1 1 Ribosomal protein L23 DNA_mis_repair PF01119.14 ABX12703.1 - 0.0018 17.7 0.1 0.0031 16.9 0.0 1.4 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain RRM_5 PF13893.1 ABX12703.1 - 0.017 14.9 0.3 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L4 PF00573.17 ABX12704.1 - 1.5e-46 158.1 0.4 1.8e-46 157.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L3 PF00297.17 ABX12705.1 - 5e-56 190.0 0.2 5.8e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Methyltrn_RNA_3 PF02598.12 ABX12706.1 - 6.8e-50 170.0 0.1 8e-50 169.8 0.1 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 ABX12706.1 - 0.0018 18.1 0.0 0.47 10.3 0.0 2.2 2 0 0 2 2 2 2 SpoU rRNA Methylase family Proteasome PF00227.21 ABX12707.1 - 2.4e-55 186.7 0.2 3.1e-55 186.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 ABX12707.1 - 1.5e-14 52.9 0.6 5.1e-14 51.2 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF371 PF04027.8 ABX12708.1 - 2.8e-45 153.1 0.1 3.1e-45 153.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF371) DUF1312 PF07009.6 ABX12708.1 - 0.06 13.1 0.1 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1312) WbqC PF08889.6 ABX12709.1 - 0.024 14.0 0.4 0.03 13.7 0.3 1.2 1 0 0 1 1 1 0 WbqC-like protein family SPC12 PF06645.8 ABX12710.1 - 1.6 8.6 4.3 2.1 8.1 1.0 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Copper-bind PF00127.15 ABX12711.1 - 7.5e-10 38.9 0.0 3.8e-09 36.6 0.0 2.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family DUF2089 PF09862.4 ABX12711.1 - 9.9e-08 31.7 0.4 1 9.1 0.0 4.2 4 1 1 5 5 5 3 Protein of unknown function (DUF2089) AF0941-like PF14591.1 ABX12711.1 - 1.7e-07 31.3 8.2 0.044 13.8 0.2 3.7 2 1 2 4 4 4 3 AF0941-like THDPS_N_2 PF14805.1 ABX12711.1 - 6.3e-07 29.1 0.5 2.8 7.8 0.0 5.4 3 2 3 6 6 6 2 Tetrahydrodipicolinate N-succinyltransferase N-terminal GatB_Yqey PF02637.13 ABX12711.1 - 0.0002 21.1 3.4 2.6 7.7 0.1 4.6 3 2 1 4 4 4 1 GatB domain PAH PF02671.16 ABX12711.1 - 0.0013 18.3 0.4 20 4.9 0.0 3.7 4 0 0 4 4 4 0 Paired amphipathic helix repeat DUF2150 PF09920.4 ABX12711.1 - 0.0013 18.4 0.5 6.5 6.2 0.1 3.9 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2150) DUF1212 PF06738.7 ABX12711.1 - 0.0034 16.8 0.1 3.9 6.8 0.0 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1212) DUF2335 PF10097.4 ABX12711.1 - 0.0048 16.4 0.0 10 5.8 0.0 3.1 3 0 0 3 3 3 2 Predicted membrane protein (DUF2335) DUF1160 PF06648.6 ABX12711.1 - 0.0087 15.8 0.2 2.3 8.0 0.0 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1160) PhageMin_Tail PF10145.4 ABX12711.1 - 0.053 13.1 0.0 0.39 10.3 0.0 2.1 1 1 0 2 2 2 0 Phage-related minor tail protein PMBR PF09373.5 ABX12711.1 - 0.062 13.2 0.1 1.4e+02 2.6 0.0 3.9 4 0 0 4 4 4 0 Pseudomurein-binding repeat AAA_29 PF13555.1 ABX12711.1 - 0.12 11.9 0.0 22 4.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain SPT2 PF08243.6 ABX12711.1 - 0.13 12.6 0.4 0.39 11.0 0.3 1.8 1 0 0 1 1 1 0 SPT2 chromatin protein Snf7 PF03357.16 ABX12712.1 - 1.5e-07 31.0 1.4 2.4e-07 30.2 1.0 1.4 1 1 0 1 1 1 1 Snf7 Sulphotransf PF09037.5 ABX12712.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Stf0 sulphotransferase Redoxin PF08534.5 ABX12713.1 - 7.4e-09 35.2 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 ABX12713.1 - 3.3e-08 33.2 0.0 5.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 ABX12713.1 - 0.0021 18.1 0.1 0.0047 17.0 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like Tcp10_C PF07202.8 ABX12713.1 - 0.053 13.0 0.1 0.089 12.3 0.1 1.3 1 0 0 1 1 1 0 T-complex protein 10 C-terminus DsbD PF02683.10 ABX12714.1 - 1.7e-44 151.9 18.7 1.9e-44 151.7 12.9 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.1 ABX12714.1 - 1.3e-07 31.6 16.4 1.7e-07 31.1 11.4 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF2910 PF11139.3 ABX12714.1 - 0.00084 18.5 6.6 0.28 10.2 3.6 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2910) DUF2116 PF09889.4 ABX12714.1 - 0.59 9.9 2.6 3.6 7.4 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Baculo_11_kDa PF06143.6 ABX12714.1 - 7.9 5.9 9.4 1.7 8.0 0.1 2.6 3 0 0 3 3 3 0 Baculovirus 11 kDa family Aminotran_1_2 PF00155.16 ABX12715.1 - 1.1e-57 195.6 0.0 1.3e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 ABX12715.1 - 6.7e-05 21.3 0.1 0.0001 20.7 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 ABX12715.1 - 0.00087 18.5 0.1 0.0022 17.2 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 ABX12715.1 - 0.0087 14.8 0.1 0.014 14.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Peptidase_M10 PF00413.19 ABX12716.1 - 1.9e-10 40.6 0.2 3.8e-10 39.7 0.2 1.5 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 ABX12716.1 - 9.1e-06 25.1 0.1 1.2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 ABX12716.1 - 0.0015 18.0 1.8 0.0062 16.0 0.6 1.9 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 ABX12716.1 - 0.002 18.6 0.3 0.0035 17.8 0.2 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 ABX12716.1 - 0.0072 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_5 PF13688.1 ABX12716.1 - 0.032 14.1 0.1 0.066 13.1 0.2 1.6 2 1 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 ABX12716.1 - 0.052 13.6 0.8 0.099 12.6 0.6 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 ABX12716.1 - 0.09 12.4 0.1 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M43 PF05572.8 ABX12716.1 - 0.12 11.9 1.3 0.22 11.0 0.4 1.9 1 1 1 2 2 2 0 Pregnancy-associated plasma protein-A BATS PF06968.8 ABX12717.1 - 5.5e-22 77.4 0.0 1.6e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 ABX12717.1 - 1.1e-18 67.9 0.9 2.6e-18 66.7 0.4 1.8 2 0 0 2 2 2 1 Radical SAM superfamily MRP-S28 PF10213.4 ABX12717.1 - 0.063 13.3 0.0 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein ATP_bind_3 PF01171.15 ABX12717.1 - 0.065 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family DUF1471 PF07338.8 ABX12717.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Aminotran_3 PF00202.16 ABX12718.1 - 1.5e-88 296.9 0.3 1.8e-88 296.6 0.2 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 ABX12718.1 - 0.0078 15.3 0.0 0.016 14.3 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase TBPIP_N PF15517.1 ABX12718.1 - 0.046 13.3 0.8 0.19 11.4 0.6 1.9 2 0 0 2 2 2 0 TBP-interacting protein N-terminus PAGK PF15284.1 ABX12718.1 - 0.066 12.9 0.2 0.29 10.8 0.1 2.0 2 0 0 2 2 2 0 Phage-encoded virulence factor AAA_26 PF13500.1 ABX12719.1 - 9.7e-40 136.3 0.1 1.1e-39 136.1 0.1 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 ABX12719.1 - 5.9e-13 48.6 0.3 7.8e-13 48.2 0.2 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.4 ABX12719.1 - 0.0021 17.8 0.2 0.0044 16.8 0.1 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like DUF1611 PF07755.6 ABX12719.1 - 0.0021 16.7 0.5 0.035 12.7 0.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1611) ArsA_ATPase PF02374.10 ABX12719.1 - 0.1 11.5 0.5 8.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase TrmB PF01978.14 ABX12720.1 - 4.8e-05 22.9 0.0 6.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 ABX12720.1 - 0.0016 17.9 0.1 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit HxlR PF01638.12 ABX12720.1 - 0.0016 18.0 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix Sulfolobus_pRN PF05584.6 ABX12720.1 - 0.008 16.1 0.0 0.0094 15.8 0.0 1.1 1 0 0 1 1 1 1 Sulfolobus plasmid regulatory protein Snf7 PF03357.16 ABX12720.1 - 0.013 14.8 0.9 0.019 14.3 0.6 1.3 1 1 0 1 1 1 0 Snf7 DUF4423 PF14394.1 ABX12720.1 - 0.028 13.9 0.1 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF387 PF04079.11 ABX12720.1 - 0.042 13.2 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) B-block_TFIIIC PF04182.7 ABX12720.1 - 0.042 13.7 0.1 0.05 13.4 0.1 1.1 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_45 PF14947.1 ABX12720.1 - 0.044 13.5 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_34 PF13601.1 ABX12720.1 - 0.059 13.4 0.0 0.066 13.2 0.0 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_27 PF13463.1 ABX12720.1 - 0.061 13.6 0.0 0.068 13.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR PF01047.17 ABX12720.1 - 0.073 12.7 0.1 0.089 12.5 0.1 1.1 1 0 0 1 1 1 0 MarR family DUF2461 PF09365.5 ABX12720.1 - 0.078 12.3 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) XS PF03468.9 ABX12720.1 - 0.097 12.6 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 XS domain DUF2250 PF10007.4 ABX12720.1 - 0.14 12.0 0.2 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Band_7 PF01145.20 ABX12721.1 - 3.3e-27 95.5 7.5 5.4e-27 94.8 5.2 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF3867 PF12983.2 ABX12721.1 - 0.081 12.9 0.8 0.12 12.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) Thioredoxin_3 PF13192.1 ABX12722.1 - 0.034 13.9 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Orthopox_A36R PF05950.6 ABX12722.1 - 0.075 12.9 0.2 0.084 12.8 0.1 1.0 1 0 0 1 1 1 0 Orthopoxvirus A36R protein DUF106 PF01956.11 ABX12722.1 - 0.67 9.4 4.1 0.91 9.0 2.9 1.3 1 1 0 1 1 1 0 Integral membrane protein DUF106 NapE PF06796.6 ABX12722.1 - 5.8 6.2 5.8 1.8 7.9 1.5 1.9 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE DUF3919 PF13057.1 ABX12723.1 - 0.016 14.6 2.6 0.74 9.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3919) Lipase_GDSL_3 PF14606.1 ABX12723.1 - 0.079 12.7 0.1 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family GatB_Yqey PF02637.13 ABX12723.1 - 0.083 12.6 0.8 0.19 11.4 0.1 1.8 2 0 0 2 2 2 0 GatB domain DUF2335 PF10097.4 ABX12723.1 - 0.094 12.3 0.5 0.96 9.1 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) IL31 PF15209.1 ABX12723.1 - 0.15 11.6 3.7 0.28 10.7 0.7 2.1 2 1 0 2 2 2 0 Interleukin 31 HMG_CoA_synt_C PF08540.5 ABX12724.1 - 3.9e-33 115.1 0.1 6.1e-33 114.4 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 ABX12724.1 - 3.4e-30 104.8 0.2 6.1e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Thioredoxin_4 PF13462.1 ABX12725.1 - 3.9e-28 98.5 0.0 4.8e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 ABX12725.1 - 6.8e-15 55.1 0.0 1.4e-13 50.8 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 ABX12725.1 - 9.8e-05 22.5 0.0 0.0004 20.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ABX12725.1 - 0.042 13.9 0.0 5.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like RWD PF05773.17 ABX12726.1 - 0.012 15.4 0.2 0.025 14.4 0.1 1.6 1 1 0 1 1 1 0 RWD domain Gp_dh_N PF00044.19 ABX12727.1 - 0.00016 21.6 0.0 0.0089 15.9 0.0 2.5 1 1 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 ABX12727.1 - 0.0036 17.2 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 ABX12727.1 - 0.027 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 ABX12727.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF21 PF01595.15 ABX12728.1 - 2.5e-53 180.1 0.0 3.7e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CorC_HlyC PF03471.12 ABX12728.1 - 3.2e-18 65.2 1.3 3.2e-18 65.2 0.9 2.3 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.23 ABX12728.1 - 1.7e-17 62.9 0.1 3.7e-08 33.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain PALP PF00291.20 ABX12729.1 - 6.3e-42 143.8 0.0 8.6e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PK_C PF02887.11 ABX12729.1 - 0.09 12.3 1.8 0.58 9.7 0.4 2.2 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain GRIP PF01465.15 ABX12730.1 - 0.072 12.6 0.6 0.17 11.4 0.4 1.6 1 0 0 1 1 1 0 GRIP domain YxiJ PF14176.1 ABX12730.1 - 0.078 13.1 4.5 0.14 12.2 0.8 2.2 1 1 1 2 2 2 0 YxiJ-like protein Sec5 PF15469.1 ABX12731.1 - 0.00043 20.0 0.8 0.0017 18.1 0.5 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec5 IFT20 PF14931.1 ABX12731.1 - 0.003 17.4 1.3 1.2 9.0 0.1 2.1 2 0 0 2 2 2 2 Intraflagellar transport complex B, subunit 20 NPV_P10 PF05531.7 ABX12731.1 - 0.056 13.7 1.3 4.6 7.5 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1993 PF09351.5 ABX12731.1 - 0.097 12.5 0.1 0.21 11.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) Phage_connect_1 PF05135.8 ABX12731.1 - 0.55 10.4 2.8 15 5.8 0.1 2.1 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein Trypan_PARP PF05887.6 ABX12732.1 - 0.0078 16.0 67.8 0.065 13.0 34.2 2.4 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) Hjc PF01870.13 ABX12733.1 - 7.2e-05 22.3 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) Lipoprotein_7 PF01540.11 ABX12734.1 - 0.0085 15.1 0.4 0.0086 15.1 0.3 1.0 1 0 0 1 1 1 1 Adhesin lipoprotein EB1 PF03271.12 ABX12734.1 - 0.058 13.4 1.9 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 EB1-like C-terminal motif DUF2730 PF10805.3 ABX12734.1 - 0.068 12.9 1.6 0.073 12.8 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) APG6 PF04111.7 ABX12734.1 - 0.11 11.4 3.6 0.12 11.4 2.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF35_N PF12172.3 ABX12736.1 - 0.0032 17.3 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2602 PF10782.4 ABX12736.1 - 1.3 8.9 5.9 15 5.4 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2602) Thiolase_C PF02803.13 ABX12737.1 - 1.1e-13 50.6 0.6 3.1e-13 49.2 0.2 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 ABX12737.1 - 3e-05 23.1 0.0 0.00011 21.2 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 ABX12737.1 - 0.0061 16.1 0.0 0.021 14.4 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.17 ABX12737.1 - 0.0062 16.3 2.4 0.027 14.3 0.5 2.7 2 1 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Dodecin PF07311.7 ABX12737.1 - 0.0072 16.3 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 Dodecin ketoacyl-synt PF00109.21 ABX12737.1 - 0.039 13.4 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Bac_luciferase PF00296.15 ABX12738.1 - 1.4e-56 191.9 0.0 1.7e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase NTP_transferase PF00483.18 ABX12739.1 - 4.5e-30 104.7 0.2 6.5e-30 104.2 0.2 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 ABX12739.1 - 4.3e-12 46.3 0.0 4.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 ABX12739.1 - 0.0087 15.5 0.0 0.019 14.4 0.0 1.5 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Imm25 PF15571.1 ABX12739.1 - 0.038 14.1 5.2 0.62 10.1 0.5 2.4 2 0 0 2 2 2 0 Immunity protein 25 DUF4047 PF13256.1 ABX12740.1 - 0.047 13.6 0.9 0.05 13.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF2680 PF10925.3 ABX12740.1 - 0.31 10.9 2.1 0.44 10.4 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) DUF308 PF03729.8 ABX12741.1 - 0.0091 15.9 0.8 0.0091 15.9 0.5 3.0 2 1 0 2 2 2 1 Short repeat of unknown function (DUF308) TraX PF05857.6 ABX12741.1 - 0.22 11.1 1.6 0.24 11.0 1.1 1.1 1 0 0 1 1 1 0 TraX protein DUF4418 PF14387.1 ABX12741.1 - 0.74 9.5 7.7 2.9 7.6 5.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4418) Bax1-I PF01027.15 ABX12741.1 - 0.76 9.3 7.2 1.2 8.6 5.0 1.4 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 ABC2_membrane_4 PF12730.2 ABX12741.1 - 4.2 6.4 9.5 6 5.9 6.6 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein ATP-grasp PF02222.17 ABX12742.1 - 1.7e-59 200.0 0.1 2.7e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 ABX12742.1 - 1.1e-18 67.5 0.1 1.9e-18 66.8 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ABX12742.1 - 1.9e-10 40.5 0.1 4e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 ABX12742.1 - 3.2e-07 29.4 0.0 7.7e-06 24.8 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 ABX12742.1 - 1.8e-06 27.9 0.1 3.7e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain DUF1297 PF06973.7 ABX12742.1 - 0.0019 17.5 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) ATP-grasp_2 PF08442.5 ABX12742.1 - 0.0036 16.7 0.4 1.9 7.7 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp domain TrkA_N PF02254.13 ABX12742.1 - 0.006 16.5 0.4 0.14 12.1 0.0 3.1 3 1 1 4 4 4 1 TrkA-N domain RimK PF08443.6 ABX12742.1 - 0.0062 16.0 0.1 0.046 13.1 0.1 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 ABX12742.1 - 0.013 15.0 0.1 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 2-Hacid_dh_C PF02826.14 ABX12742.1 - 0.032 13.3 0.1 0.076 12.1 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 ABX12742.1 - 0.15 10.6 0.1 0.24 9.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 ABX12742.1 - 0.24 11.8 1.9 0.91 9.9 0.0 2.8 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AIRC PF00731.15 ABX12743.1 - 2.8e-57 192.2 0.7 3.9e-57 191.7 0.5 1.2 1 0 0 1 1 1 1 AIR carboxylase DUF719 PF05334.8 ABX12743.1 - 0.046 13.7 0.1 0.074 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF719) PrpR_N PF06506.6 ABX12743.1 - 0.069 12.5 0.1 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Propionate catabolism activator Fes1 PF08609.5 ABX12743.1 - 0.077 13.4 0.1 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 PALP PF00291.20 ABX12744.1 - 6.4e-79 265.3 2.7 1.1e-78 264.6 1.8 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.20 ABX12744.1 - 9.8e-05 21.7 0.2 0.00028 20.2 0.1 1.8 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 ABX12744.1 - 0.00014 22.1 0.3 0.00039 20.7 0.2 1.7 1 0 0 1 1 1 1 ACT domain Thr_dehydrat_C PF00585.13 ABX12744.1 - 0.0058 16.2 0.0 0.05 13.2 0.0 2.2 2 0 0 2 2 2 1 C-terminal regulatory domain of Threonine dehydratase PGM_PMM_II PF02879.11 ABX12744.1 - 0.1 12.9 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ATP-synt_F6 PF05511.6 ABX12745.1 - 0.011 15.6 1.4 0.018 14.9 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DUF87 PF01935.12 ABX12745.1 - 0.38 10.5 3.3 1.4 8.6 2.3 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF87 Toxin_64 PF15542.1 ABX12745.1 - 0.73 10.4 5.2 1.5 9.4 0.1 2.8 1 1 2 3 3 3 0 Putative toxin 64 Guanylate_cyc PF00211.15 ABX12746.1 - 4.9e-19 68.4 0.1 7e-19 67.8 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DivIC PF04977.10 ABX12747.1 - 0.00087 18.7 1.0 0.0017 17.7 0.7 1.5 1 0 0 1 1 1 1 Septum formation initiator HALZ PF02183.13 ABX12747.1 - 0.035 13.8 5.6 0.062 13.0 3.9 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Shugoshin_N PF07558.6 ABX12747.1 - 0.057 13.1 2.3 0.19 11.4 1.6 1.9 1 1 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.16 ABX12747.1 - 0.16 11.9 7.1 0.3 11.0 4.9 1.5 1 0 0 1 1 1 0 bZIP transcription factor Herpes_BLRF2 PF05812.7 ABX12747.1 - 0.75 9.6 7.2 1.2 8.9 5.0 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF972 PF06156.8 ABX12747.1 - 1.2 9.5 4.9 1.1 9.5 1.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Glyoxalase_2 PF12681.2 ABX12749.1 - 4.8e-16 59.2 0.0 5.9e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 ABX12749.1 - 2.2e-09 37.3 0.0 4.5e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 ABX12749.1 - 0.0079 16.1 0.0 0.44 10.5 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AsnC_trans_reg PF01037.16 ABX12750.1 - 6.9e-08 32.0 0.1 8.4e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 AsnC family ACT_4 PF13291.1 ABX12750.1 - 0.013 15.8 0.5 0.029 14.6 0.3 1.6 1 1 1 2 2 2 0 ACT domain GYD PF08734.6 ABX12750.1 - 0.03 14.0 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 GYD domain YjgF_endoribonc PF14588.1 ABX12750.1 - 0.073 12.9 0.0 0.075 12.9 0.0 1.0 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease AsnC_trans_reg PF01037.16 ABX12751.1 - 0.00088 18.9 0.7 0.0014 18.3 0.5 1.3 1 1 0 1 1 1 1 AsnC family PTPS PF01242.14 ABX12751.1 - 0.043 13.4 0.1 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase DUF503 PF04456.7 ABX12751.1 - 0.078 12.5 0.3 0.091 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF503) RC-P840_PscD PF10657.4 ABX12751.1 - 0.13 12.1 1.6 0.14 11.9 1.1 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD FctA PF12892.2 ABX12753.1 - 0.11 13.2 1.6 0.16 12.8 1.0 1.4 1 1 0 1 1 1 0 T surface-antigen of pili Cob_adeno_trans PF01923.13 ABX12754.1 - 1.1e-58 197.6 0.0 1.2e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF1931 PF09123.6 ABX12754.1 - 0.004 17.1 0.1 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1931) HD_3 PF13023.1 ABX12755.1 - 3.5e-38 130.9 0.9 4.1e-38 130.7 0.6 1.0 1 0 0 1 1 1 1 HD domain HD PF01966.17 ABX12755.1 - 9.2e-07 28.9 0.2 2.2e-06 27.6 0.1 1.6 1 1 0 1 1 1 1 HD domain DUF2448 PF10476.4 ABX12755.1 - 0.051 13.1 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) HDOD PF08668.7 ABX12755.1 - 0.06 12.6 0.1 0.11 11.7 0.0 1.5 1 1 1 2 2 2 0 HDOD domain SMP_2 PF10144.4 ABX12755.1 - 0.072 12.2 0.4 0.14 11.2 0.3 1.4 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin DUF1767 PF08585.7 ABX12755.1 - 0.22 11.8 1.5 0.93 9.8 0.7 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF1767) TFIIS_M PF07500.9 ABX12755.1 - 0.33 11.0 5.6 0.6 10.1 0.3 2.2 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS), central domain DUF4579 PF15158.1 ABX12756.1 - 0.022 14.2 0.1 0.026 14.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) DUF1492 PF07374.6 ABX12756.1 - 0.038 14.0 0.9 0.058 13.5 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1492) DUF2321 PF10083.4 ABX12757.1 - 0.085 12.3 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Saccharop_dh_N PF04455.7 ABX12759.1 - 3.6e-38 129.8 0.4 8.6e-38 128.6 0.3 1.6 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region DUF1188 PF06690.6 ABX12759.1 - 0.017 14.2 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) SHOCT PF09851.4 ABX12760.1 - 0.00036 19.8 0.1 0.00071 18.9 0.1 1.6 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.7 ABX12760.1 - 0.011 15.4 0.3 0.011 15.4 0.2 1.8 2 1 0 2 2 2 0 Gas vesicle protein G RIC3 PF15361.1 ABX12760.1 - 0.084 13.1 0.1 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Aminotran_1_2 PF00155.16 ABX12761.1 - 8.5e-40 136.8 0.0 1.1e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ABX12761.1 - 0.0032 16.6 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase AMP-binding PF00501.23 ABX12762.1 - 1.2e-83 280.8 0.0 1.5e-83 280.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ABX12762.1 - 4.9e-13 49.8 0.0 1e-12 48.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GatB_N PF02934.10 ABX12764.1 - 1.3e-97 326.2 0.0 1.9e-97 325.6 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 ABX12764.1 - 7.3e-33 113.3 4.2 1.4e-32 112.4 2.9 1.5 1 0 0 1 1 1 1 GatB domain TMP_2 PF06791.8 ABX12764.1 - 0.014 14.9 0.1 0.035 13.7 0.1 1.6 2 0 0 2 2 2 0 Prophage tail length tape measure protein PSDC PF12588.3 ABX12764.1 - 0.056 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Phophatidylserine decarboxylase Amidase PF01425.16 ABX12765.1 - 3e-131 438.3 0.1 3.4e-131 438.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Glu-tRNAGln PF02686.10 ABX12766.1 - 0.13 12.0 1.7 0.45 10.3 1.2 1.9 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit tRNA-synt_2 PF00152.15 ABX12767.1 - 8.3e-85 284.4 0.9 2.3e-84 283.0 0.6 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 ABX12767.1 - 1.2e-11 44.3 0.1 2.1e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 ABX12767.1 - 0.024 13.8 0.3 0.077 12.1 0.0 1.9 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) DUF1297 PF06973.7 ABX12768.1 - 1.4e-74 249.5 0.2 1.8e-74 249.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.7 ABX12768.1 - 4.1e-48 162.2 0.0 6.5e-48 161.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) ATP-grasp_3 PF02655.9 ABX12768.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain BPD_transp_1 PF00528.17 ABX12769.1 - 8.7e-20 71.0 14.5 8.7e-20 71.0 10.1 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component MotA_ExbB PF01618.11 ABX12769.1 - 0.087 12.4 0.3 0.087 12.4 0.2 1.8 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family DUF3154 PF11351.3 ABX12769.1 - 0.74 9.5 4.1 11 5.8 2.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) PrgI PF12666.2 ABX12769.1 - 4.2 7.5 17.3 0.2 11.8 0.8 3.7 3 1 1 4 4 4 0 PrgI family protein ABC_tran PF00005.22 ABX12770.1 - 2.3e-34 118.6 0.2 3.3e-34 118.1 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ABX12770.1 - 1.2e-10 41.8 1.2 1.6e-07 31.5 0.8 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 ABX12770.1 - 3e-07 29.8 3.5 1.9e-05 23.9 2.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ABX12770.1 - 4.6e-06 26.0 0.1 1e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 ABX12770.1 - 0.00049 20.2 1.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ABX12770.1 - 0.0014 18.6 0.2 0.0049 16.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 ABX12770.1 - 0.0016 17.9 2.9 0.0017 17.8 0.5 1.9 1 1 1 2 2 2 1 AAA-like domain AAA_23 PF13476.1 ABX12770.1 - 0.0021 18.4 1.0 0.0039 17.5 0.7 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ABX12770.1 - 0.0022 17.1 0.1 0.0051 15.9 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin DUF258 PF03193.11 ABX12770.1 - 0.0024 17.0 0.1 0.0038 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 KaiC PF06745.8 ABX12770.1 - 0.0032 16.6 0.6 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 KaiC AAA_17 PF13207.1 ABX12770.1 - 0.0068 17.2 0.1 0.02 15.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ABX12770.1 - 0.021 14.2 0.3 0.063 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 ABX12770.1 - 0.028 14.2 0.9 0.082 12.7 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function DUF87 Miro PF08477.8 ABX12770.1 - 0.029 14.8 0.1 0.077 13.5 0.1 1.8 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 ABX12770.1 - 0.035 13.9 0.6 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 ABX12770.1 - 0.038 13.4 0.1 0.097 12.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 ABX12770.1 - 0.065 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_18 PF13238.1 ABX12770.1 - 0.071 13.4 1.0 0.11 12.7 0.2 1.9 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ABX12770.1 - 0.088 12.5 0.4 0.48 10.1 0.0 2.2 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) MobB PF03205.9 ABX12770.1 - 0.092 12.4 0.4 0.32 10.6 0.0 2.0 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 ABX12770.1 - 0.12 11.9 1.3 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 ABX12770.1 - 0.13 12.2 0.8 0.26 11.2 0.4 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 ABX12770.1 - 0.13 11.8 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.15 ABX12770.1 - 0.22 10.1 2.7 0.076 11.6 0.2 1.7 2 1 0 2 2 2 0 G-protein alpha subunit Phosphonate-bd PF12974.2 ABX12771.1 - 1.9e-45 155.1 0.2 2.4e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Transferrin PF00405.12 ABX12771.1 - 2.7e-05 23.2 0.0 6.1e-05 22.0 0.0 1.5 1 1 1 2 2 2 1 Transferrin SBP_bac_3 PF00497.15 ABX12771.1 - 5.4e-05 22.5 0.0 0.00012 21.4 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.1 ABX12771.1 - 0.00029 20.2 0.1 0.0017 17.7 0.0 2.2 2 1 1 3 3 3 1 NMT1-like family YhfZ_C PF14503.1 ABX12771.1 - 0.0064 15.8 0.0 0.57 9.4 0.0 2.4 2 0 0 2 2 2 1 YhfZ C-terminal domain NMT1 PF09084.6 ABX12771.1 - 0.066 12.8 0.0 0.65 9.5 0.0 2.1 2 0 0 2 2 2 0 NMT1/THI5 like TrmB PF01978.14 ABX12772.1 - 2.3e-06 27.2 0.1 3.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 ABX12772.1 - 6.9e-05 22.5 0.0 9.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.10 ABX12772.1 - 0.00016 21.4 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.7 ABX12772.1 - 0.00025 20.6 0.1 0.00042 19.9 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.15 ABX12772.1 - 0.00041 19.9 0.1 0.00083 18.9 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DUF1492 PF07374.6 ABX12772.1 - 0.0014 18.6 0.2 0.002 18.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1492) Mga PF05043.8 ABX12772.1 - 0.0015 18.7 0.7 0.0031 17.7 0.3 1.6 1 1 0 1 1 1 1 Mga helix-turn-helix domain HTH_23 PF13384.1 ABX12772.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Fe_dep_repress PF01325.14 ABX12772.1 - 0.0023 17.8 0.1 0.0038 17.1 0.1 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.1 ABX12772.1 - 0.0028 17.0 0.1 0.0057 16.0 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF4423 PF14394.1 ABX12772.1 - 0.0051 16.3 0.1 0.0061 16.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) FUR PF01475.14 ABX12772.1 - 0.0054 16.6 0.1 0.0075 16.1 0.1 1.4 1 1 0 1 1 1 1 Ferric uptake regulator family HTH_28 PF13518.1 ABX12772.1 - 0.0072 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 ABX12772.1 - 0.0082 15.5 0.1 0.015 14.7 0.1 1.5 1 1 0 1 1 1 1 Sigma-70, region 4 DDE_Tnp_2 PF04693.7 ABX12772.1 - 0.028 13.4 0.1 0.034 13.1 0.1 1.1 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 HTH_40 PF14493.1 ABX12772.1 - 0.03 14.5 0.4 0.048 13.8 0.2 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.5 ABX12772.1 - 0.03 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_22 PF13309.1 ABX12772.1 - 0.033 13.9 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.2 ABX12772.1 - 0.062 12.9 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 MarR family TFIIE_alpha PF02002.12 ABX12772.1 - 0.067 12.6 0.1 0.078 12.4 0.1 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit GerE PF00196.14 ABX12772.1 - 0.069 12.4 0.1 0.14 11.4 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF2250 PF10007.4 ABX12772.1 - 0.084 12.7 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_36 PF13730.1 ABX12772.1 - 0.086 12.9 0.2 0.14 12.2 0.2 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.15 ABX12772.1 - 0.13 12.4 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_45 PF14947.1 ABX12772.1 - 0.17 11.6 0.7 0.52 10.1 0.2 2.0 1 1 1 2 2 2 0 Winged helix-turn-helix HTH_20 PF12840.2 ABX12773.1 - 3.6e-08 33.0 0.1 5.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TFIIE_alpha PF02002.12 ABX12773.1 - 1.5e-05 24.4 0.3 1.8e-05 24.1 0.2 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit TrmB PF01978.14 ABX12773.1 - 2.2e-05 24.0 0.3 5.1e-05 22.8 0.2 1.8 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB DUF742 PF05331.6 ABX12773.1 - 0.001 18.6 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF742) MarR_2 PF12802.2 ABX12773.1 - 0.0021 17.7 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.7 ABX12773.1 - 0.0038 16.8 0.2 0.0073 15.9 0.2 1.5 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.5 ABX12773.1 - 0.0078 15.7 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain Mga PF05043.8 ABX12773.1 - 0.02 15.1 0.2 0.13 12.5 0.1 2.1 2 0 0 2 2 2 0 Mga helix-turn-helix domain PadR PF03551.9 ABX12773.1 - 0.025 14.3 0.2 0.06 13.1 0.1 1.6 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family HTH_24 PF13412.1 ABX12773.1 - 0.029 13.7 0.9 0.057 12.8 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding ArsR PF09824.4 ABX12773.1 - 0.033 13.5 0.1 0.042 13.1 0.1 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator Mrr_N PF14338.1 ABX12773.1 - 0.051 13.6 0.2 0.23 11.5 0.1 1.9 1 1 0 1 1 1 0 Mrr N-terminal domain HTH_5 PF01022.15 ABX12773.1 - 0.053 13.2 0.1 0.085 12.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF2250 PF10007.4 ABX12773.1 - 0.069 13.0 0.2 0.094 12.6 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DUF1492 PF07374.6 ABX12773.1 - 0.069 13.2 0.1 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) YycC PF14174.1 ABX12773.1 - 0.12 12.0 0.1 0.33 10.6 0.0 1.7 1 1 0 1 1 1 0 YycC-like protein CbtA PF09490.5 ABX12774.1 - 1.6e-18 66.8 0.3 2e-18 66.5 0.2 1.1 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) INSIG PF07281.7 ABX12774.1 - 0.011 15.0 0.1 0.39 10.0 0.0 2.2 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) DUF4401 PF14351.1 ABX12774.1 - 0.023 13.7 1.4 0.061 12.2 1.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) DUF1624 PF07786.7 ABX12774.1 - 0.14 11.5 3.4 0.092 12.0 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1624) DUF3816 PF12822.2 ABX12774.1 - 7.7 6.3 18.6 0.41 10.5 6.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3816) MFS_1 PF07690.11 ABX12774.1 - 8.9 4.9 17.8 5.2 5.6 9.9 2.4 2 1 0 2 2 2 0 Major Facilitator Superfamily CbtB PF09489.5 ABX12775.1 - 1e-06 28.4 9.2 1.2e-06 28.3 1.7 2.2 1 1 1 2 2 2 2 Probable cobalt transporter subunit (CbtB) DUF4443 PF14544.1 ABX12776.1 - 5.5e-06 26.2 0.0 8.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4443) HTH_45 PF14947.1 ABX12776.1 - 0.00049 19.8 0.3 0.001 18.8 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 ABX12776.1 - 0.041 13.5 0.8 0.076 12.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) Thioredoxin_4 PF13462.1 ABX12777.1 - 6.6e-33 114.0 0.0 7.8e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 ABX12777.1 - 1.1e-13 51.1 0.0 2e-12 47.0 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 ABX12777.1 - 2.4e-07 30.9 0.1 1.5e-06 28.3 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 ABX12777.1 - 9.9e-05 21.9 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin eRF1_2 PF03464.10 ABX12778.1 - 5.8e-29 101.1 0.0 1.5e-28 99.8 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 ABX12778.1 - 3.5e-20 72.3 0.2 3.7e-19 69.0 0.0 2.2 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 ABX12778.1 - 9.4e-19 67.2 0.2 2.9e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 1 SpoU_sub_bind PF08032.7 ABX12778.1 - 0.024 14.7 0.0 0.16 12.1 0.0 2.4 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF3795 PF12675.2 ABX12778.1 - 0.13 12.4 0.4 0.24 11.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) HIT PF01230.18 ABX12779.1 - 8.8e-24 83.9 0.2 1.1e-23 83.5 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 ABX12779.1 - 1.3e-13 51.2 0.1 1.6e-13 50.9 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2749 PF10907.3 ABX12780.1 - 0.0055 16.5 0.2 0.093 12.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2749) Lar_restr_allev PF14354.1 ABX12781.1 - 0.012 15.8 0.1 0.015 15.5 0.1 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF2225 PF09986.4 ABX12781.1 - 0.037 13.4 1.7 0.074 12.5 1.2 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF2082 PF09855.4 ABX12781.1 - 0.14 12.0 1.9 0.29 10.9 1.3 1.6 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) TFIIS_C PF01096.13 ABX12781.1 - 0.15 11.6 2.1 2.7 7.7 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-RING_4 PF14570.1 ABX12781.1 - 0.17 11.4 2.3 8.1 6.1 0.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 ABX12781.1 - 0.17 11.8 1.0 2.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.14 ABX12781.1 - 0.19 11.3 1.0 1.3 8.7 0.1 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2387 PF09526.5 ABX12781.1 - 0.5 10.3 2.4 5.1 7.0 1.4 2.1 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) zf-Sec23_Sec24 PF04810.10 ABX12781.1 - 0.71 9.4 2.7 8.6 6.0 0.6 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger TF_Zn_Ribbon PF08271.7 ABX12781.1 - 1.9 7.8 5.3 26 4.2 0.2 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding ILVD_EDD PF00920.16 ABX12782.1 - 7.9e-217 720.7 6.5 9e-217 720.6 4.5 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1263 PF06882.7 ABX12782.1 - 0.024 14.2 0.0 1.6 8.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) Helicase_C_2 PF13307.1 ABX12784.1 - 4.1e-23 82.1 0.0 1.2e-22 80.6 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 ABX12784.1 - 4e-06 26.3 0.4 4e-06 26.3 0.3 1.7 2 0 0 2 2 2 1 DEAD_2 GIY-YIG PF01541.19 ABX12785.1 - 4.6e-07 30.1 0.3 6.1e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain DUF1162 PF06650.7 ABX12785.1 - 0.043 13.0 0.2 0.049 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1162) DUF2613 PF11021.3 ABX12786.1 - 0.00094 18.8 0.2 0.0015 18.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) DUF2140 PF09911.4 ABX12788.1 - 0.18 10.9 1.6 3.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Streptin-Immun PF11083.3 ABX12788.1 - 0.45 10.5 5.7 10 6.1 2.3 2.8 1 1 0 2 2 2 0 Lantibiotic streptin immunity protein zinc_ribbon_5 PF13719.1 ABX12790.1 - 0.019 14.5 0.3 0.019 14.5 0.2 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ABX12790.1 - 0.023 14.3 0.4 0.023 14.3 0.3 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-DNL PF05180.7 ABX12790.1 - 0.088 12.5 1.4 0.22 11.2 1.0 1.8 1 1 0 1 1 1 0 DNL zinc finger C1_4 PF07975.7 ABX12790.1 - 0.67 10.0 5.6 1.1 9.2 3.9 1.6 1 1 0 1 1 1 0 TFIIH C1-like domain Lipocalin PF00061.18 ABX12794.1 - 0.048 13.6 0.3 0.072 13.0 0.0 1.5 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family YdfZ PF14001.1 ABX12795.1 - 0.023 14.9 0.0 0.032 14.4 0.0 1.1 1 0 0 1 1 1 0 YdfZ protein PcrB PF01884.12 ABX12796.1 - 0.043 13.0 0.1 0.049 12.8 0.1 1.2 1 0 0 1 1 1 0 PcrB family RPA_C PF08784.6 ABX12797.1 - 0.0084 16.5 0.0 0.0092 16.3 0.0 1.1 1 0 0 1 1 1 1 Replication protein A C terminal FaeA PF04703.7 ABX12797.1 - 0.012 15.7 0.2 0.016 15.3 0.1 1.1 1 0 0 1 1 1 0 FaeA-like protein DUF3895 PF13034.1 ABX12797.1 - 0.012 15.0 3.0 1.7 8.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) Snf7 PF03357.16 ABX12797.1 - 0.017 14.4 0.4 0.02 14.3 0.3 1.1 1 0 0 1 1 1 0 Snf7 z-alpha PF02295.12 ABX12797.1 - 0.018 14.7 0.3 0.023 14.4 0.2 1.1 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain PMC2NT PF08066.7 ABX12797.1 - 0.12 12.6 0.1 0.18 12.1 0.1 1.3 1 1 0 1 1 1 0 PMC2NT (NUC016) domain SHOCT PF09851.4 ABX12798.1 - 3.3e-06 26.3 4.2 3.3e-06 26.3 2.9 2.7 2 0 0 2 2 2 1 Short C-terminal domain ENT PF03735.9 ABX12798.1 - 0.0079 15.8 6.3 0.039 13.6 0.8 2.5 2 1 0 2 2 2 1 ENT domain Nif11 PF07862.6 ABX12798.1 - 0.015 15.1 0.2 0.066 13.1 0.1 2.2 2 1 0 2 2 2 0 Nitrogen fixation protein of unknown function DUF2422 PF10337.4 ABX12798.1 - 0.072 11.8 6.4 0.086 11.6 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) MRP-S23 PF10484.4 ABX12798.1 - 0.27 11.1 7.2 1.2 9.0 1.1 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 ATP-synt_B PF00430.13 ABX12798.1 - 2.1 8.1 12.8 3.9 7.2 8.0 2.1 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) NPHI_C PF08469.5 ABX12799.1 - 0.078 12.8 2.5 0.088 12.7 1.5 1.4 1 1 0 1 1 1 0 Nucleoside triphosphatase I C-terminal Fib_alpha PF08702.5 ABX12799.1 - 0.15 12.1 3.1 0.22 11.6 2.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APOBEC_C PF05240.9 ABX12799.1 - 0.34 10.3 0.1 0.34 10.3 0.1 2.5 3 0 0 3 3 3 0 APOBEC-like C-terminal domain Corona_S2 PF01601.11 ABX12799.1 - 0.57 8.2 7.3 0.75 7.8 5.1 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF3091 PF11291.3 ABX12799.1 - 0.68 9.9 7.2 0.16 11.9 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) APG5 PF04106.7 ABX12799.1 - 6.6 6.1 8.0 6.5 6.1 2.4 2.2 1 1 1 2 2 2 0 Autophagy protein Apg5 Mob_Pre PF01076.14 ABX12800.1 - 0.12 12.0 2.4 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 Plasmid recombination enzyme Neur_chan_memb PF02932.11 ABX12801.1 - 1.5 8.6 5.6 2.8 7.7 3.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PDDEXK_1 PF12705.2 ABX12802.1 - 1.6e-11 44.1 2.7 3.2e-10 39.8 1.9 2.0 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF2800 PF10926.3 ABX12802.1 - 0.0038 16.3 0.7 0.037 13.1 0.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2800) DUF3799 PF12684.2 ABX12802.1 - 0.007 15.7 1.6 0.007 15.7 1.1 1.7 2 0 0 2 2 2 1 PDDEXK-like domain of unknown function (DUF3799) Exo5 PF09810.4 ABX12802.1 - 0.023 13.9 1.0 0.046 12.9 0.5 1.3 1 1 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease CheZ PF04344.8 ABX12802.1 - 0.026 14.1 0.3 0.041 13.5 0.0 1.6 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Rad50_zn_hook PF04423.9 ABX12804.1 - 0.0021 17.5 3.5 0.09 12.2 0.1 2.4 2 0 0 2 2 2 2 Rad50 zinc hook motif MscS_porin PF12795.2 ABX12804.1 - 0.01 15.2 4.4 0.011 15.0 3.1 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain XPC-binding PF09280.6 ABX12804.1 - 0.022 14.2 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 XPC-binding domain Suppressor_APC PF11414.3 ABX12804.1 - 0.027 14.2 0.3 0.036 13.8 0.2 1.2 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Laminin_II PF06009.7 ABX12804.1 - 0.054 13.2 0.2 0.059 13.1 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II PEARLI-4 PF05278.7 ABX12804.1 - 0.092 12.1 2.7 0.1 11.9 1.9 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Syntaxin_2 PF14523.1 ABX12804.1 - 0.12 12.4 0.5 0.12 12.3 0.3 1.1 1 0 0 1 1 1 0 Syntaxin-like protein HTH_AraC PF00165.18 ABX12804.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF3810 PF12725.2 ABX12804.1 - 0.14 11.0 0.4 0.15 10.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) KIP1 PF07765.7 ABX12804.1 - 0.19 11.5 1.5 0.65 9.8 0.4 1.9 1 1 1 2 2 2 0 KIP1-like protein Pox_polyA_pol_N PF12630.2 ABX12804.1 - 0.24 11.5 1.1 0.33 11.0 0.8 1.3 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain TMF_DNA_bd PF12329.3 ABX12804.1 - 0.4 10.5 4.7 0.79 9.5 3.2 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TINF2_N PF14973.1 ABX12805.1 - 0.038 14.1 0.5 0.04 14.0 0.3 1.2 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus TipAS PF07739.8 ABX12805.1 - 0.11 12.7 0.6 0.17 12.1 0.1 1.5 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain Pox_A11 PF05061.8 ABX12805.1 - 0.14 11.1 1.6 0.15 11.0 1.1 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein Med26 PF08711.6 ABX12805.1 - 0.45 10.0 3.0 0.53 9.8 1.3 1.8 1 1 1 2 2 2 0 TFIIS helical bundle-like domain FliS PF02561.9 ABX12805.1 - 0.78 9.6 4.8 16 5.3 3.3 2.1 1 1 0 1 1 1 0 Flagellar protein FliS DUF848 PF05852.6 ABX12806.1 - 0.86 9.4 5.0 1.4 8.7 1.5 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Chorismate_bind PF00425.13 ABX12807.1 - 1.1e-91 306.7 0.0 4.5e-91 304.7 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 ABX12807.1 - 3.4e-23 82.2 0.1 2.7e-20 72.7 0.0 3.0 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region DSS1_SEM1 PF05160.8 ABX12807.1 - 0.57 9.9 5.3 0.62 9.8 1.0 2.4 2 0 0 2 2 2 0 DSS1/SEM1 family GATase PF00117.23 ABX12808.1 - 1.5e-56 190.8 0.1 1.7e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ABX12808.1 - 2e-11 43.7 0.0 3.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 ABX12808.1 - 0.0085 15.5 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family Response_reg PF00072.19 ABX12808.1 - 0.024 14.6 0.0 0.059 13.3 0.0 1.6 2 0 0 2 2 2 0 Response regulator receiver domain Glyco_trans_4_2 PF13477.1 ABX12808.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like Glycos_transf_3 PF00591.16 ABX12809.1 - 2.1e-78 263.2 1.0 2.1e-78 263.2 0.7 1.4 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 ABX12809.1 - 3.6e-15 55.3 0.1 7.7e-15 54.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Sigma70_r1_1 PF03979.9 ABX12809.1 - 0.065 13.1 0.2 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 IGPS PF00218.16 ABX12810.1 - 1.7e-70 236.9 0.5 2e-70 236.7 0.4 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.14 ABX12810.1 - 1.2e-05 24.8 0.0 2.8e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 ABX12810.1 - 0.00016 20.7 0.5 0.00041 19.3 0.2 1.8 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 ABX12810.1 - 0.0028 16.5 0.0 0.0094 14.8 0.0 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.12 ABX12810.1 - 0.0049 16.1 0.0 0.0092 15.2 0.0 1.5 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.16 ABX12810.1 - 0.012 14.9 0.0 0.025 13.8 0.0 1.7 1 0 0 1 1 1 0 Histidine biosynthesis protein AP_endonuc_2 PF01261.19 ABX12810.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Cellulase PF00150.13 ABX12810.1 - 0.018 14.2 0.1 0.035 13.3 0.1 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) DUF556 PF04476.8 ABX12810.1 - 0.024 13.8 0.2 0.061 12.5 0.0 1.7 3 0 0 3 3 3 0 Protein of unknown function (DUF556) DHO_dh PF01180.16 ABX12810.1 - 0.041 12.8 0.9 3.4 6.5 0.0 2.4 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase EAL PF00563.15 ABX12810.1 - 0.059 12.8 0.2 13 5.2 0.1 2.5 2 1 0 3 3 3 0 EAL domain PALP PF00291.20 ABX12811.1 - 3.3e-43 148.0 0.9 4.4e-43 147.6 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trp_syntA PF00290.15 ABX12812.1 - 1.6e-85 285.8 1.2 1.9e-85 285.5 0.8 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.16 ABX12812.1 - 1.3e-07 31.1 0.2 4.6e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.16 ABX12812.1 - 1.7e-06 27.2 0.8 2.3e-06 26.7 0.5 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 ABX12812.1 - 2e-06 27.2 0.6 9.1e-06 25.0 0.2 2.2 2 0 0 2 2 2 1 PcrB family FMN_dh PF01070.13 ABX12812.1 - 2.2e-05 23.4 0.2 0.00011 21.1 0.0 2.0 1 1 0 2 2 2 1 FMN-dependent dehydrogenase BtpA PF03437.10 ABX12812.1 - 3.7e-05 23.0 1.1 0.0028 16.9 0.8 2.2 1 1 1 2 2 2 1 BtpA family IMPDH PF00478.20 ABX12812.1 - 0.00033 19.6 1.4 0.0011 17.9 0.7 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 ABX12812.1 - 0.00058 19.0 0.1 0.0015 17.6 0.1 1.6 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG IGPS PF00218.16 ABX12812.1 - 0.00074 18.6 0.0 0.045 12.8 0.0 2.2 1 1 1 2 2 2 1 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.12 ABX12812.1 - 0.0033 16.5 1.1 0.0098 15.0 0.8 2.1 1 1 0 1 1 1 1 Thiamine monophosphate synthase/TENI NanE PF04131.9 ABX12812.1 - 0.0057 15.6 0.2 0.028 13.3 0.1 2.2 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase PEP_mutase PF13714.1 ABX12812.1 - 0.013 14.6 0.0 13 4.8 0.0 2.9 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase NMO PF03060.10 ABX12812.1 - 0.015 14.4 0.0 0.038 13.1 0.0 1.7 2 0 0 2 2 2 0 Nitronate monooxygenase GDPD PF03009.12 ABX12812.1 - 0.051 13.0 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family TGT PF01702.13 ABX12812.1 - 0.11 11.7 0.0 0.32 10.2 0.0 1.8 2 1 0 2 2 2 0 Queuine tRNA-ribosyltransferase Ribul_P_3_epim PF00834.14 ABX12812.1 - 0.12 11.4 0.3 0.18 10.8 0.2 1.4 1 1 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Response_reg PF00072.19 ABX12812.1 - 0.14 12.2 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Response regulator receiver domain MSP7_C PF12948.2 ABX12813.1 - 0.02 15.1 2.6 0.062 13.5 1.0 2.5 1 1 1 2 2 2 0 MSP7-like protein C-terminal domain Copper-bind PF00127.15 ABX12814.1 - 0.00042 20.5 0.0 0.0012 19.0 0.0 1.7 2 0 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family CTP_synth_N PF06418.9 ABX12815.1 - 7.3e-122 405.7 0.1 1.1e-121 405.2 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 ABX12815.1 - 1.9e-50 170.9 0.0 3.4e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ABX12815.1 - 2.2e-12 46.8 0.0 9.4e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 ABX12815.1 - 9.9e-07 28.3 0.1 1.9e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3068 PF11271.3 ABX12816.1 - 5e-56 189.9 0.4 8.2e-56 189.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3068) HATPase_c PF02518.21 ABX12816.1 - 5.2e-26 90.5 0.2 9.4e-26 89.7 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ABX12816.1 - 2.3e-12 46.7 0.1 4.7e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 ABX12816.1 - 1.6e-06 27.7 0.1 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 ABX12816.1 - 0.0039 16.8 0.0 0.008 15.8 0.0 1.6 1 0 0 1 1 1 1 GHKL domain NAD_kinase PF01513.16 ABX12817.1 - 1.8e-34 118.8 0.3 2.5e-34 118.3 0.2 1.2 1 0 0 1 1 1 1 ATP-NAD kinase TrmB PF01978.14 ABX12817.1 - 1.1e-05 25.0 1.5 0.001 18.7 0.2 2.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 ABX12817.1 - 2.4e-05 23.9 0.6 6.3e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.1 ABX12817.1 - 0.00014 22.1 0.4 0.00032 20.9 0.2 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.1 ABX12817.1 - 0.00015 21.0 0.6 0.00076 18.8 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding RNA_pol_Rpc34 PF05158.7 ABX12817.1 - 0.00043 19.5 0.5 0.00063 19.0 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR_2 PF12802.2 ABX12817.1 - 0.00049 19.7 0.1 0.0012 18.4 0.0 1.7 1 0 0 1 1 1 1 MarR family FeoC PF09012.5 ABX12817.1 - 0.034 13.8 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 FeoC like transcriptional regulator TFIIE_alpha PF02002.12 ABX12817.1 - 0.13 11.8 1.4 0.36 10.3 0.3 2.3 2 1 1 3 3 3 0 TFIIE alpha subunit PfkB PF00294.19 ABX12818.1 - 3.4e-13 49.3 0.2 2e-12 46.8 0.2 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase NTNH_C PF08470.5 ABX12818.1 - 0.00016 21.3 0.3 0.00072 19.2 0.0 1.9 2 0 0 2 2 2 1 Nontoxic nonhaemagglutinin C-terminal Phos_pyr_kin PF08543.7 ABX12818.1 - 0.0053 15.9 0.0 0.007 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Macscav_rec PF03523.8 ABX12818.1 - 0.012 15.3 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 Macrophage scavenger receptor Ribosomal_S26e PF01283.14 ABX12819.1 - 1e-33 115.9 1.5 1.1e-33 115.8 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e PHD PF00628.24 ABX12819.1 - 0.056 13.1 0.2 9.4 6.0 0.0 2.2 2 0 0 2 2 2 0 PHD-finger zf-like PF04071.7 ABX12819.1 - 0.062 13.0 0.8 0.25 11.0 0.1 1.9 1 1 1 2 2 2 0 Cysteine-rich small domain zf-ribbon_3 PF13248.1 ABX12819.1 - 0.11 11.6 0.3 0.11 11.6 0.2 1.7 2 0 0 2 2 2 0 zinc-ribbon domain DUF3279 PF11682.3 ABX12819.1 - 0.15 11.6 1.1 0.52 9.8 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) zinc_ribbon_4 PF13717.1 ABX12819.1 - 0.23 11.1 2.0 0.63 9.7 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 ABX12819.1 - 0.25 10.9 2.3 0.64 9.6 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 ABX12819.1 - 0.37 10.4 2.4 9.6 5.9 0.1 2.7 2 1 1 3 3 3 0 Transcription factor S-II (TFIIS) CDP-OH_P_transf PF01066.16 ABX12820.1 - 2.3e-16 59.9 10.0 1.1e-15 57.7 7.0 1.9 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Arginase PF00491.16 ABX12821.1 - 2.9e-66 223.6 0.1 3.8e-66 223.2 0.1 1.0 1 0 0 1 1 1 1 Arginase family tRNA-Thr_ED PF08915.6 ABX12822.1 - 1.9e-49 167.1 0.3 3.3e-49 166.4 0.2 1.4 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase tRNA-synt_2b PF00587.20 ABX12822.1 - 6.3e-26 90.9 0.7 1.5e-25 89.7 0.5 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ABX12822.1 - 4.1e-25 87.5 0.5 8.5e-25 86.5 0.3 1.6 1 0 0 1 1 1 1 Anticodon binding domain DUF1896 PF08989.5 ABX12823.1 - 0.044 13.6 0.0 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) DS PF01916.12 ABX12824.1 - 1.6e-55 188.3 0.2 1.9e-55 188.0 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Ribosomal_S25 PF03297.10 ABX12826.1 - 5.5e-06 26.3 3.1 5.9e-06 26.2 2.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein TrmB PF01978.14 ABX12826.1 - 0.0043 16.7 0.1 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF977 PF06163.6 ABX12826.1 - 0.016 14.9 0.2 0.02 14.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_24 PF13412.1 ABX12826.1 - 0.019 14.3 0.1 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 ABX12826.1 - 0.056 13.1 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.1 ABX12826.1 - 0.072 12.8 0.1 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.17 ABX12826.1 - 0.072 12.8 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 MarR family Cyclophil_like PF04126.8 ABX12827.1 - 8.2e-09 35.1 0.0 1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin-like RNA_pol_Rpb6 PF01192.17 ABX12828.1 - 6.8e-13 48.1 3.4 1.2e-12 47.3 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb6 Cauli_AT PF03233.8 ABX12828.1 - 0.41 10.3 3.9 0.58 9.8 2.7 1.2 1 0 0 1 1 1 0 Aphid transmission protein Alba PF01918.16 ABX12829.1 - 5.3e-12 45.1 0.5 6.7e-12 44.8 0.3 1.2 1 0 0 1 1 1 1 Alba RNase_HII PF01351.13 ABX12829.1 - 0.022 14.3 0.1 0.025 14.2 0.1 1.1 1 0 0 1 1 1 0 Ribonuclease HII SWM_repeat PF13753.1 ABX12829.1 - 0.039 13.0 0.2 0.048 12.7 0.2 1.1 1 0 0 1 1 1 0 Putative flagellar system-associated repeat HTH_19 PF12844.2 ABX12830.1 - 6.9e-06 26.0 0.2 0.00033 20.6 0.0 2.2 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.17 ABX12830.1 - 3.9e-05 23.4 0.0 0.00011 21.9 0.0 1.9 1 1 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.1 ABX12830.1 - 0.0082 15.7 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.7 ABX12830.1 - 0.035 13.7 0.0 0.082 12.5 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_26 PF13443.1 ABX12830.1 - 0.049 13.8 0.1 0.17 12.1 0.0 1.8 1 1 1 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.1 ABX12830.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain Rpr2 PF04032.11 ABX12830.1 - 0.13 12.1 0.4 0.44 10.4 0.2 1.9 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Asn_synthase PF00733.16 ABX12831.1 - 1e-34 120.2 0.0 3.2e-33 115.2 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 ABX12831.1 - 0.00016 20.6 0.1 0.00047 19.1 0.0 1.7 2 0 0 2 2 2 1 NAD synthase QueC PF06508.8 ABX12831.1 - 0.0004 19.7 0.3 0.0017 17.6 0.1 2.2 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC DZR PF12773.2 ABX12831.1 - 0.0024 17.6 2.0 0.028 14.2 0.8 2.3 2 0 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.1 ABX12831.1 - 0.0026 16.9 4.1 0.0026 16.9 2.8 1.8 2 0 0 2 2 2 1 zinc-ribbon domain tRNA_Me_trans PF03054.11 ABX12831.1 - 0.0093 14.5 0.0 0.016 13.7 0.0 1.5 1 0 0 1 1 1 1 tRNA methyl transferase zinc_ribbon_2 PF13240.1 ABX12831.1 - 0.02 14.3 4.2 0.084 12.3 3.0 2.0 1 1 0 1 1 1 0 zinc-ribbon domain Cript PF10235.4 ABX12831.1 - 0.03 14.6 3.6 0.35 11.2 0.6 2.6 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT ATP_bind_3 PF01171.15 ABX12831.1 - 0.041 13.3 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 PP-loop family ThiI PF02568.9 ABX12831.1 - 0.05 13.0 0.1 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Aldo_ket_red PF00248.16 ABX12833.1 - 3.1e-33 114.7 0.0 6.4e-33 113.7 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family DUF321 PF03778.8 ABX12833.1 - 0.13 11.7 0.3 0.27 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF321) UbiA PF01040.13 ABX12834.1 - 1.1e-29 103.5 17.6 1.5e-29 102.9 12.2 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Phage_holin_2 PF04550.7 ABX12834.1 - 0.18 11.8 0.1 0.18 11.8 0.1 3.5 4 0 0 4 4 4 0 Phage holin family 2 DUF2203 PF09969.4 ABX12835.1 - 2.1e-38 131.1 0.3 2.4e-38 131.0 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) Bet_v_1 PF00407.14 ABX12835.1 - 0.043 13.4 0.2 0.093 12.3 0.1 1.5 2 0 0 2 2 2 0 Pathogenesis-related protein Bet v I family SANTA PF09133.5 ABX12836.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 SANTA (SANT Associated) Pyridox_oxidase PF01243.15 ABX12837.1 - 4.4e-11 42.6 0.0 5.6e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 ABX12837.1 - 4.1e-08 33.1 0.0 4.8e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.7 ABX12837.1 - 0.048 13.2 0.2 0.067 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Rotamase_3 PF13616.1 ABX12838.1 - 4.2e-27 94.7 0.2 4.9e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 ABX12838.1 - 1.8e-26 92.6 0.1 2.1e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 ABX12838.1 - 5.8e-12 46.3 0.0 7e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain PapD_C PF02753.12 ABX12838.1 - 0.044 13.6 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain NTPase_I-T PF01931.13 ABX12838.1 - 0.068 12.9 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF84 DEAD PF00270.24 ABX12840.1 - 4.3e-20 71.8 0.1 2.2e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ABX12840.1 - 2.7e-19 68.7 0.1 6.3e-19 67.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ABX12840.1 - 8.5e-17 61.5 0.0 3.2e-16 59.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 ABX12840.1 - 0.00017 21.3 0.0 0.00041 20.1 0.0 1.6 1 1 0 1 1 1 1 Flavivirus DEAD domain SNF2_N PF00176.18 ABX12840.1 - 0.00057 18.7 0.0 0.00091 18.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.1 ABX12840.1 - 0.0084 15.8 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Helicase_C_2 PF13307.1 ABX12840.1 - 0.015 15.2 0.0 0.76 9.7 0.0 2.4 2 0 0 2 2 2 0 Helicase C-terminal domain Spectrin PF00435.16 ABX12841.1 - 0.079 13.2 0.3 0.11 12.7 0.2 1.3 1 1 0 1 1 1 0 Spectrin repeat ART PF01129.13 ABX12842.1 - 0.037 13.1 0.5 0.038 13.0 0.4 1.1 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase DUF4473 PF14747.1 ABX12842.1 - 0.096 12.9 3.5 0.11 12.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) FAM75 PF14650.1 ABX12842.1 - 0.12 11.7 1.6 0.12 11.6 1.1 1.0 1 0 0 1 1 1 0 FAM75 family DUF1542 PF07564.6 ABX12842.1 - 0.17 11.9 6.0 0.71 9.9 4.2 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1542) Activator-TraM PF11657.3 ABX12842.1 - 0.2 11.1 4.1 0.22 10.9 2.9 1.0 1 0 0 1 1 1 0 Transcriptional activator TraM Cut12 PF11500.3 ABX12842.1 - 1.1 8.8 8.5 1.2 8.7 5.9 1.0 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Bap31 PF05529.7 ABX12842.1 - 3.8 6.9 6.2 4 6.8 4.3 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like dCMP_cyt_deam_1 PF00383.17 ABX12843.1 - 9.5e-26 89.4 1.0 1.3e-25 89.0 0.7 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DNA_pol_B PF00136.16 ABX12844.1 - 2.2e-87 293.8 6.0 3.1e-87 293.3 4.2 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 ABX12844.1 - 4.8e-44 150.5 4.2 7.9e-44 149.8 2.9 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.1 ABX12844.1 - 6e-07 29.4 1.9 1.8e-06 27.8 1.3 1.8 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 ABX12844.1 - 2.9e-06 26.9 1.2 8.4e-06 25.4 0.8 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Vmethyltransf_C PF08456.5 ABX12844.1 - 0.13 11.6 4.3 0.16 11.3 0.4 2.2 2 0 0 2 2 2 0 Viral methyltransferase C-terminal MtN3_slv PF03083.11 ABX12845.1 - 1.9e-09 37.2 3.0 2.1e-09 37.1 2.1 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.9 ABX12845.1 - 0.00011 21.6 2.2 0.0002 20.8 1.5 1.5 1 0 0 1 1 1 1 PQ loop repeat Zip PF02535.17 ABX12845.1 - 0.089 11.7 0.5 0.13 11.2 0.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1624 PF07786.7 ABX12845.1 - 0.12 11.7 3.0 0.13 11.5 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) DUF3784 PF12650.2 ABX12845.1 - 1.3 8.9 11.3 5.2 7.0 7.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) DUF2976 PF11190.3 ABX12845.1 - 1.9 8.0 9.3 0.55 9.7 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) DUF3487 PF11990.3 ABX12845.1 - 2.4 7.5 6.2 1 8.7 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF3955 PF13127.1 ABX12845.1 - 4.5 6.8 10.5 0.15 11.6 1.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3955) VirB3 PF05101.8 ABX12845.1 - 5.8 6.9 6.3 9.2 6.3 1.3 2.2 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein TIM PF00121.13 ABX12846.1 - 8.6e-30 103.5 6.9 2.4e-20 72.6 0.8 2.0 1 1 1 2 2 2 2 Triosephosphate isomerase IGPS PF00218.16 ABX12846.1 - 7.7e-05 21.8 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase ThiG PF05690.9 ABX12846.1 - 0.00029 20.0 0.2 0.00044 19.3 0.1 1.4 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.13 ABX12846.1 - 0.004 16.0 0.1 0.008 15.0 0.0 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Zea_mays_MuDR PF05928.6 ABX12846.1 - 0.057 12.8 0.3 1.9 7.8 0.0 2.2 1 1 0 2 2 2 0 Zea mays MURB-like protein (MuDR) PcrB PF01884.12 ABX12846.1 - 0.066 12.4 2.6 0.054 12.7 0.5 1.9 2 1 0 2 2 2 0 PcrB family PEP-utilizers_C PF02896.13 ABX12847.1 - 4.1e-90 301.6 0.8 6.9e-90 300.8 0.6 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.14 ABX12847.1 - 3.9e-59 200.3 0.0 1.9e-58 198.0 0.0 2.0 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 ABX12847.1 - 7.8e-20 70.2 0.1 2.8e-19 68.4 0.1 2.0 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Phage_connect_1 PF05135.8 ABX12847.1 - 0.034 14.3 0.9 0.19 11.8 0.1 2.5 3 0 0 3 3 3 0 Phage gp6-like head-tail connector protein HTH_3 PF01381.17 ABX12848.1 - 2.3e-15 56.1 0.4 4e-15 55.4 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix CBS PF00571.23 ABX12848.1 - 1.7e-14 53.3 0.1 8.3e-11 41.5 0.0 2.3 2 0 0 2 2 2 2 CBS domain HTH_19 PF12844.2 ABX12848.1 - 1.5e-11 44.1 0.6 3e-11 43.1 0.2 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.1 ABX12848.1 - 2.6e-08 33.9 0.0 4.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 ABX12848.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 ABX12848.1 - 0.0029 17.3 0.2 0.0072 16.1 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.1 ABX12848.1 - 0.0049 17.0 0.3 0.0096 16.1 0.2 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Sigma70_r4 PF04545.11 ABX12848.1 - 0.051 12.8 0.1 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Death PF00531.17 ABX12848.1 - 0.087 12.5 0.0 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 Death domain HTH_Crp_2 PF13545.1 ABX12848.1 - 0.11 12.3 0.1 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Glyoxalase_4 PF13669.1 ABX12849.1 - 7.2e-23 80.6 0.1 8.4e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 ABX12849.1 - 3.6e-13 49.5 0.0 3.9e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 ABX12849.1 - 2.7e-11 43.6 0.0 2.9e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.2 ABX12849.1 - 2.5e-07 31.2 0.0 2.9e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain MM_CoA_mutase PF01642.17 ABX12850.1 - 1e-188 627.7 0.0 1.2e-188 627.5 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase PAP_PilO PF06864.7 ABX12850.1 - 0.0078 14.6 0.0 0.029 12.7 0.0 1.8 2 0 0 2 2 2 1 Pilin accessory protein (PilO) Pik1 PF11522.3 ABX12850.1 - 0.12 12.1 0.1 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 ArgK PF03308.11 ABX12851.1 - 1.8e-74 249.8 5.9 2.2e-74 249.6 4.1 1.1 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 ABX12851.1 - 1.6e-07 30.9 0.6 7.4e-07 28.7 0.1 2.2 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 ABX12851.1 - 2.9e-07 29.8 0.0 1.1e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 KAP family P-loop domain ATP_bind_1 PF03029.12 ABX12851.1 - 2.3e-06 27.3 0.8 0.0049 16.4 0.2 2.5 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein DUF258 PF03193.11 ABX12851.1 - 0.00017 20.8 0.5 0.00047 19.3 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 ABX12851.1 - 0.00021 20.8 0.5 0.00045 19.7 0.3 1.5 1 1 0 1 1 1 1 AAA-like domain MobB PF03205.9 ABX12851.1 - 0.0012 18.6 1.7 0.0057 16.3 0.2 2.6 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 ABX12851.1 - 0.0068 16.4 0.0 0.017 15.1 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain Ubiq_cyt_C_chap PF03981.7 ABX12851.1 - 0.0069 16.2 0.7 0.014 15.2 0.5 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone ABC_tran PF00005.22 ABX12851.1 - 0.014 15.6 1.0 0.051 13.8 0.1 2.3 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 ABX12851.1 - 0.015 16.0 1.6 0.035 14.9 0.3 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ABX12851.1 - 0.016 14.9 2.8 0.086 12.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 ABX12851.1 - 0.022 15.0 11.4 0.11 12.8 1.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 ABX12851.1 - 0.023 14.2 0.6 0.023 14.2 0.4 1.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 ABX12851.1 - 0.024 14.1 1.8 0.052 13.1 0.2 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 ABX12851.1 - 0.035 14.2 1.9 0.35 11.0 0.8 2.8 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 ABX12851.1 - 0.043 13.7 2.6 0.16 11.9 1.8 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 ABX12851.1 - 0.043 13.5 0.9 0.094 12.4 0.1 2.1 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.17 ABX12851.1 - 0.046 12.5 0.5 0.046 12.5 0.4 1.8 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 ABX12851.1 - 0.05 12.6 0.3 0.05 12.6 0.2 1.8 2 0 0 2 2 2 0 Zeta toxin RNA_pol_Rpb1_3 PF04983.13 ABX12851.1 - 0.083 12.6 1.8 0.11 12.2 0.2 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 3 PhoH PF02562.11 ABX12851.1 - 0.087 12.0 1.8 0.12 11.5 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_35 PF14516.1 ABX12851.1 - 0.092 11.3 0.8 0.16 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 ABX12851.1 - 0.11 12.1 0.4 0.22 11.0 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Trypan_glycop PF00913.14 ABX12851.1 - 0.32 9.8 4.9 0.12 11.2 0.9 1.8 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) AAA_18 PF13238.1 ABX12851.1 - 0.46 10.8 3.2 0.49 10.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain Peptidase_M1 PF01433.15 ABX12853.1 - 1.2e-139 465.7 0.6 1.6e-139 465.3 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 ABX12853.1 - 3.2e-62 210.6 0.0 9.3e-62 209.1 0.0 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 ABX12853.1 - 1.5e-19 70.3 0.1 2.4e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2265 PF10023.4 ABX12853.1 - 0.053 12.6 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) B12-binding PF02310.14 ABX12854.1 - 1e-20 73.8 0.2 1.3e-20 73.5 0.1 1.0 1 0 0 1 1 1 1 B12 binding domain IMPDH PF00478.20 ABX12854.1 - 0.0037 16.1 0.0 0.0043 15.9 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PcrB PF01884.12 ABX12854.1 - 0.077 12.2 0.9 0.18 11.0 0.2 1.7 1 1 1 2 2 2 0 PcrB family His_biosynth PF00977.16 ABX12854.1 - 0.092 12.0 0.4 0.73 9.0 0.1 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein IlvN PF07991.7 ABX12855.1 - 2.2e-66 222.2 0.4 3.1e-66 221.7 0.3 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 ABX12855.1 - 4.4e-49 166.1 0.2 6.5e-49 165.5 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 ABX12855.1 - 2.5e-06 26.7 0.1 4.3e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 ABX12855.1 - 6.9e-05 22.7 0.3 0.00047 20.0 0.1 2.2 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ABX12855.1 - 0.00021 21.6 0.2 0.00044 20.6 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 ABX12855.1 - 0.0045 16.8 0.2 0.0093 15.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CTP_transf_2 PF01467.21 ABX12856.1 - 1.7e-13 50.9 0.0 2.2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Citrate_ly_lig PF08218.6 ABX12856.1 - 0.00018 21.0 0.2 0.0031 16.9 0.0 2.1 1 1 1 2 2 2 1 Citrate lyase ligase C-terminal domain HIGH_NTase1 PF05636.6 ABX12856.1 - 0.0076 15.3 0.1 0.24 10.4 0.0 2.1 2 0 0 2 2 2 1 HIGH Nucleotidyl Transferase FAD_syn PF06574.7 ABX12856.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.4 1 1 0 1 1 1 0 FAD synthetase NTNH_C PF08470.5 ABX12856.1 - 0.032 13.8 0.5 0.062 12.9 0.1 1.7 1 1 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal CFTR_R PF14396.1 ABX12856.1 - 0.06 12.6 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain GTP_EFTU_D2 PF03144.20 ABX12857.1 - 8.4e-09 35.4 0.2 1.9e-08 34.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 ABX12857.1 - 0.027 14.1 1.6 0.052 13.1 0.3 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 DUF900 PF05990.7 ABX12858.1 - 7.6e-10 38.5 0.1 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF726 PF05277.7 ABX12858.1 - 1.6e-09 37.0 0.0 2.4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 ABX12858.1 - 1.6e-05 24.5 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 ABX12858.1 - 2e-05 23.9 1.1 0.00026 20.3 0.8 2.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 ABX12858.1 - 0.00046 19.2 0.0 0.00072 18.6 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Cutinase PF01083.17 ABX12858.1 - 0.00073 19.3 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 ABX12858.1 - 0.0014 18.4 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 ABX12858.1 - 0.0014 17.6 0.0 0.0022 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF2305 PF10230.4 ABX12858.1 - 0.0035 16.7 0.1 0.0045 16.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_8 PF06259.7 ABX12858.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase VirJ PF06057.6 ABX12858.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PGAP1 PF07819.8 ABX12858.1 - 0.092 12.3 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein tRNA-synt_1g PF09334.6 ABX12859.1 - 3.4e-135 450.6 1.6 4.4e-135 450.3 1.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ABX12859.1 - 1e-19 70.0 0.6 7.8e-08 30.7 0.1 4.2 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 ABX12859.1 - 2.3e-12 46.6 0.7 3.7e-06 26.3 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 ABX12859.1 - 1.6e-07 31.1 0.0 3.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.13 ABX12859.1 - 9e-07 27.8 0.1 0.00095 17.9 0.0 3.2 3 0 0 3 3 3 1 tRNA synthetases class I (K) FhuF PF06276.7 ABX12859.1 - 0.0055 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter Ribosomal_L37e PF01907.14 ABX12859.1 - 0.038 13.7 1.3 0.076 12.8 0.9 1.5 1 0 0 1 1 1 0 Ribosomal protein L37e tRNA-synt_1d PF00750.14 ABX12859.1 - 0.049 12.4 0.3 1.1 7.9 0.0 2.3 1 1 1 2 2 2 0 tRNA synthetases class I (R) zf-Di19 PF05605.7 ABX12859.1 - 0.34 11.0 3.5 0.8 9.8 2.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.1 ABX12859.1 - 1.6 8.0 8.0 61 3.0 5.5 2.3 1 1 0 1 1 1 0 zinc-ribbon domain AdoHcyase_NAD PF00670.16 ABX12860.1 - 7.5e-52 175.4 1.2 7.5e-52 175.4 0.8 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.12 ABX12860.1 - 1.9e-50 171.3 0.6 2.4e-50 170.9 0.4 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.14 ABX12860.1 - 5.1e-10 38.7 0.6 2e-09 36.8 0.1 2.1 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 ABX12860.1 - 1.5e-06 27.6 0.1 4.1e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 ABX12860.1 - 0.00031 20.8 0.3 0.025 14.6 0.1 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 ABX12860.1 - 0.0011 19.0 0.0 0.0048 16.8 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain 3HCDH_N PF02737.13 ABX12860.1 - 0.016 14.8 3.9 0.021 14.5 0.3 2.7 3 1 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF364 PF04016.7 ABX12860.1 - 0.02 14.1 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF364) THF_DHG_CYH_C PF02882.14 ABX12860.1 - 0.033 13.2 0.7 0.47 9.5 0.5 2.8 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.9 ABX12860.1 - 0.034 13.5 0.5 0.093 12.0 0.4 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rieske PF00355.21 ABX12861.1 - 2e-14 52.9 0.0 2.2e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 ABX12861.1 - 1.3e-13 50.5 0.0 1.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_synthase PF02540.12 ABX12862.1 - 1.5e-72 243.4 0.2 1.6e-72 243.2 0.2 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 ABX12862.1 - 0.00056 18.5 0.0 0.016 13.7 0.0 2.3 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 ABX12862.1 - 0.0098 15.1 0.0 0.054 12.7 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 ABX12862.1 - 0.025 14.1 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase ATP_bind_3 PF01171.15 ABX12862.1 - 0.031 13.7 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 PP-loop family HTH_23 PF13384.1 ABX12862.1 - 0.068 12.8 0.0 2.5 7.8 0.0 2.8 4 0 0 4 4 4 0 Homeodomain-like domain Clostridium_P47 PF06597.6 ABX12862.1 - 0.082 11.3 0.1 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Clostridium P-47 protein TrmB PF01978.14 ABX12862.1 - 0.092 12.4 0.3 16 5.2 0.1 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB tRNA-synt_1e PF01406.14 ABX12863.1 - 2.7e-125 417.4 1.1 2.7e-125 417.4 0.8 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 ABX12863.1 - 3.6e-14 52.2 1.9 2.6e-08 32.9 0.8 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 ABX12863.1 - 5e-11 42.6 0.7 1.4e-10 41.2 0.5 1.8 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.17 ABX12863.1 - 5.6e-08 31.2 0.7 2.6e-06 25.7 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 ABX12863.1 - 1.4e-07 30.5 0.1 0.0022 16.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1c PF00749.16 ABX12863.1 - 0.11 11.1 5.8 0.18 10.4 0.2 3.3 4 0 0 4 4 4 0 tRNA synthetases class I (E and Q), catalytic domain Citrus_P18 PF05520.6 ABX12864.1 - 0.02 14.3 0.2 0.023 14.2 0.1 1.1 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein Pyr_excise PF03013.9 ABX12865.1 - 1.8e-13 50.3 0.3 3e-13 49.6 0.2 1.4 1 1 0 1 1 1 1 Pyrimidine dimer DNA glycosylase IRF PF00605.12 ABX12865.1 - 0.018 14.8 0.1 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor CAAD PF14159.1 ABX12866.1 - 0.05 13.2 0.5 0.78 9.4 0.1 2.0 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase MS_channel PF00924.13 ABX12867.1 - 4.1e-49 166.6 1.1 5.7e-49 166.2 0.8 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel MFS_1 PF07690.11 ABX12867.1 - 0.29 9.8 10.2 0.39 9.3 7.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2976 PF11190.3 ABX12867.1 - 1 8.8 6.0 0.086 12.3 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Tetraspannin PF00335.15 ABX12867.1 - 3.5 6.8 9.7 6.3 6.0 6.8 1.4 1 1 0 1 1 1 0 Tetraspanin family DUF432 PF04254.8 ABX12868.1 - 6.9e-27 93.8 0.0 9.7e-27 93.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF432) DUF1722 PF08349.6 ABX12870.1 - 3.7e-34 117.0 3.1 6.2e-34 116.3 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) DUF2414 PF10309.4 ABX12870.1 - 0.12 12.1 0.3 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) BRCA-2_OB3 PF09104.5 ABX12870.1 - 0.55 10.0 2.7 2.4 7.9 0.6 2.2 1 1 2 3 3 3 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF650 PF04894.7 ABX12871.1 - 4.7e-88 295.2 0.0 6.2e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF650) DUF651 PF04895.7 ABX12871.1 - 2.8e-36 123.4 0.0 4.6e-36 122.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF651) Peripla_BP_2 PF01497.13 ABX12872.1 - 4.6e-47 160.1 0.2 5.5e-47 159.9 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein NAD_binding_10 PF13460.1 ABX12873.1 - 8.8e-19 68.2 0.0 1.2e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ABX12873.1 - 4.9e-12 45.6 0.0 6.8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 ABX12873.1 - 9.9e-09 34.9 0.0 2.3e-08 33.7 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ABX12873.1 - 2.3e-08 33.0 0.0 3.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ABX12873.1 - 0.00092 18.2 0.7 0.0083 15.0 0.1 2.4 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 ABX12873.1 - 0.015 14.2 0.0 0.034 13.0 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain B12-binding_2 PF02607.12 ABX12874.1 - 4.2e-12 45.9 0.0 6.6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.14 ABX12874.1 - 3e-10 39.9 0.0 5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain DUF2206 PF09971.4 ABX12874.1 - 0.21 10.3 1.4 0.32 9.7 1.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) TFIIB PF00382.14 ABX12875.1 - 2.6e-30 104.0 2.4 4.2e-17 61.7 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 ABX12875.1 - 4.6e-09 35.4 0.3 8.4e-09 34.6 0.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 ABX12875.1 - 0.00017 21.4 0.0 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 ABX12875.1 - 0.00031 20.3 0.1 0.22 11.0 0.0 2.2 1 1 1 2 2 2 2 Cyclin, N-terminal domain HTH_24 PF13412.1 ABX12875.1 - 0.0012 18.1 0.4 0.013 14.8 0.1 2.8 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 ABX12875.1 - 0.025 14.1 0.0 2.7 7.6 0.0 3.4 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Rrf2 PF02082.15 ABX12875.1 - 0.087 12.9 0.2 33 4.7 0.0 3.3 3 1 1 4 4 4 0 Transcriptional regulator GerE PF00196.14 ABX12875.1 - 0.12 11.7 0.6 12 5.3 0.1 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family MMR_HSR1_C PF08438.5 ABX12876.1 - 1.7e-32 111.8 0.0 3.7e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 ABX12876.1 - 7e-16 58.2 0.0 1.8e-15 56.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 ABX12876.1 - 2e-07 30.7 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 ABX12876.1 - 1.2e-05 24.6 0.0 0.00079 18.7 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.18 ABX12876.1 - 0.00056 19.7 1.0 0.13 12.0 0.0 3.1 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 ABX12876.1 - 0.0014 18.0 0.3 1.8 7.9 0.1 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Pterin_4a PF01329.14 ABX12877.1 - 0.0071 16.0 0.0 0.0093 15.6 0.0 1.4 1 1 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Flagellin_N PF00669.15 ABX12877.1 - 0.026 14.3 0.1 0.04 13.7 0.0 1.4 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region CoA_binding_2 PF13380.1 ABX12878.1 - 9.8e-40 135.3 0.0 1.1e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 ABX12878.1 - 1.4e-09 38.2 0.0 2.6e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 CoA binding domain Glyco_hydro_57 PF03065.10 ABX12878.1 - 0.043 12.7 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF4423 PF14394.1 ABX12879.1 - 6e-05 22.6 0.2 8e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_34 PF13601.1 ABX12879.1 - 8.9e-05 22.4 0.1 0.00013 21.8 0.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_45 PF14947.1 ABX12879.1 - 0.00027 20.6 0.1 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.14 ABX12879.1 - 0.0003 20.4 0.1 0.00044 19.9 0.1 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB EAP30 PF04157.11 ABX12879.1 - 0.0019 17.4 0.4 0.038 13.1 0.1 2.0 2 0 0 2 2 2 1 EAP30/Vps36 family TFIIE_alpha PF02002.12 ABX12879.1 - 0.0038 16.7 0.6 0.0051 16.2 0.4 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit MarR_2 PF12802.2 ABX12879.1 - 0.004 16.7 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 ABX12879.1 - 0.015 15.6 0.1 0.033 14.5 0.1 1.6 1 1 0 1 1 1 0 Winged helix DNA-binding domain A_deaminase_N PF08451.6 ABX12879.1 - 0.016 15.2 4.9 1.3 9.1 3.4 2.3 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal DUF2250 PF10007.4 ABX12879.1 - 0.026 14.3 0.3 0.054 13.3 0.1 1.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) MarR PF01047.17 ABX12879.1 - 0.054 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 MarR family DUF1018 PF06252.7 ABX12879.1 - 0.054 14.0 0.1 0.073 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) AphA_like PF14557.1 ABX12879.1 - 0.096 12.2 0.1 0.36 10.3 0.0 1.9 1 1 0 1 1 1 0 Putative AphA-like transcriptional regulator CDC37_C PF08564.5 ABX12879.1 - 0.097 12.5 1.3 0.15 11.9 0.9 1.3 1 0 0 1 1 1 0 Cdc37 C terminal domain BPL_LplA_LipB PF03099.14 ABX12880.1 - 1.2e-21 76.9 0.0 2.5e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.7 ABX12880.1 - 8.1e-15 54.2 0.1 3.1e-14 52.3 0.1 2.1 1 0 0 1 1 1 1 HTH domain BPL_C PF02237.12 ABX12880.1 - 3.1e-08 33.1 1.9 5.9e-08 32.2 1.3 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain UPF0122 PF04297.9 ABX12880.1 - 0.0025 17.8 0.2 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_24 PF13412.1 ABX12880.1 - 0.0038 16.5 0.0 0.0086 15.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 ABX12880.1 - 0.077 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator DUF948 PF06103.6 ABX12881.1 - 0.0015 18.3 1.5 0.048 13.5 0.2 2.2 1 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) AATF-Che1 PF13339.1 ABX12881.1 - 0.007 16.5 4.8 0.012 15.7 3.3 1.5 1 1 0 1 1 1 1 Apoptosis antagonizing transcription factor ALIX_LYPXL_bnd PF13949.1 ABX12881.1 - 0.012 14.5 3.2 0.016 14.2 2.2 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DivIVA PF05103.8 ABX12881.1 - 0.082 12.9 5.5 0.068 13.2 2.1 1.8 1 1 1 2 2 2 0 DivIVA protein DUF3571 PF12095.3 ABX12881.1 - 0.26 11.5 2.3 5.4 7.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) TMF_TATA_bd PF12325.3 ABX12881.1 - 0.29 10.8 4.2 1.1 9.0 2.9 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.7 ABX12881.1 - 0.33 11.2 3.2 19 5.5 2.2 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 ABX12881.1 - 0.37 11.1 4.5 3.2 8.1 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 ABX12881.1 - 0.4 10.5 0.1 0.4 10.5 0.0 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 ABX12881.1 - 0.76 8.1 4.9 0.79 8.0 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TPR_1 PF00515.23 ABX12882.1 - 1.9e-15 55.7 0.0 0.00037 19.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ABX12882.1 - 3.8e-14 52.0 0.0 4.2e-08 32.7 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 ABX12882.1 - 1.6e-13 49.4 0.0 0.00029 20.5 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat Peptidase_M10 PF00413.19 ABX12882.1 - 6.9e-09 35.5 0.0 1.7e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Matrixin TPR_8 PF13181.1 ABX12882.1 - 3.6e-08 32.6 0.3 0.0082 15.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ABX12882.1 - 3.7e-08 33.1 0.0 0.0033 17.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Reprolysin_5 PF13688.1 ABX12882.1 - 1.4e-07 31.6 0.0 3.8e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 TPR_16 PF13432.1 ABX12882.1 - 4.2e-07 30.4 0.0 0.00023 21.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ABX12882.1 - 7.4e-07 28.8 0.0 0.22 11.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 ABX12882.1 - 1.3e-06 28.6 0.0 0.0079 16.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ABX12882.1 - 1.8e-06 28.0 0.0 0.26 12.0 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ABX12882.1 - 1.8e-05 24.5 0.0 0.49 10.3 0.0 3.4 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 ABX12882.1 - 4.3e-05 23.6 0.0 0.87 10.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 ABX12882.1 - 5.4e-05 22.6 0.0 0.41 10.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Reprolysin_2 PF13574.1 ABX12882.1 - 0.00041 20.4 0.3 0.0071 16.4 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Apc3 PF12895.2 ABX12882.1 - 0.00048 20.2 0.2 0.061 13.4 0.0 2.8 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ABX12882.1 - 0.0015 18.3 0.0 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Peptidase_M57 PF12388.3 ABX12882.1 - 0.0041 16.4 0.0 0.0075 15.6 0.0 1.4 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.1 ABX12882.1 - 0.0084 16.6 0.2 0.025 15.1 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 ABX12882.1 - 0.016 14.9 0.2 0.04 13.6 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M54 Reprolysin PF01421.14 ABX12882.1 - 0.037 13.6 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Peptidase_M66 PF10462.4 ABX12882.1 - 0.04 12.7 0.0 0.089 11.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.8 ABX12882.1 - 0.069 12.7 0.1 0.23 11.0 0.1 1.8 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF4363 PF14276.1 ABX12882.1 - 0.14 11.9 2.3 0.32 10.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) TFIIB PF00382.14 ABX12883.1 - 2.5e-34 116.9 6.5 4e-18 64.9 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 ABX12883.1 - 8.5e-15 53.7 1.0 2e-14 52.6 0.7 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 ABX12883.1 - 3.8e-05 23.2 0.3 0.00034 20.1 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain OrfB_Zn_ribbon PF07282.6 ABX12883.1 - 8.8e-05 22.0 0.1 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 ABX12883.1 - 0.0077 15.4 2.5 0.015 14.4 1.7 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DUF2387 PF09526.5 ABX12883.1 - 0.031 14.2 0.2 0.14 12.1 0.2 2.1 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Baculo_ME53 PF06061.6 ABX12883.1 - 0.037 13.0 0.1 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 Lar_restr_allev PF14354.1 ABX12883.1 - 0.065 13.5 0.5 0.22 11.8 0.4 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar Peptidase_M13_N PF05649.8 ABX12883.1 - 0.065 12.2 1.2 0.61 9.0 1.0 2.2 2 1 0 2 2 2 0 Peptidase family M13 Prim_Zn_Ribbon PF08273.7 ABX12883.1 - 0.066 13.3 1.8 0.15 12.1 1.3 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Ribosomal_S27e PF01667.12 ABX12883.1 - 0.068 12.7 0.8 0.16 11.5 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 DZR PF12773.2 ABX12883.1 - 0.087 12.6 0.5 0.19 11.5 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon HMG_CoA_synt_C PF08540.5 ABX12883.1 - 0.12 11.8 0.1 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal Auto_anti-p27 PF06677.7 ABX12883.1 - 0.14 11.9 1.0 0.27 11.0 0.7 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) A2L_zn_ribbon PF08792.5 ABX12883.1 - 0.22 11.0 1.9 0.49 9.9 1.3 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain Pribosyltran PF00156.22 ABX12884.1 - 1.7e-10 40.7 0.4 3.6e-06 26.7 0.0 2.2 1 1 1 2 2 2 2 Phosphoribosyl transferase domain PHA_synth_III_E PF09712.5 ABX12886.1 - 2.3e-10 40.3 0.0 2.9e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Bacillus_HBL PF05791.6 ABX12886.1 - 0.0092 15.3 1.0 0.0092 15.3 0.7 2.2 1 1 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Phasin PF05597.6 ABX12886.1 - 0.02 14.6 1.1 0.043 13.5 0.2 1.7 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Microtub_assoc PF07989.6 ABX12886.1 - 0.029 14.1 5.4 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Microtubule associated SRP1_TIP1 PF00660.12 ABX12886.1 - 0.039 13.7 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 Seripauperin and TIP1 family DUF2408 PF10303.4 ABX12886.1 - 0.055 13.5 4.9 0.11 12.6 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Laminin_II PF06009.7 ABX12886.1 - 0.079 12.7 0.1 0.079 12.7 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II CCDC-167 PF15188.1 ABX12886.1 - 0.09 12.7 4.3 0.24 11.3 0.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Lge1 PF11488.3 ABX12886.1 - 0.096 12.8 0.9 2.6 8.3 0.3 2.4 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 IFP_35_N PF07334.8 ABX12886.1 - 0.32 10.9 7.6 0.41 10.6 1.3 2.6 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Seryl_tRNA_N PF02403.17 ABX12886.1 - 0.48 10.4 10.3 3 7.9 2.9 2.6 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 ABX12886.1 - 1.5 9.1 8.0 6.5 7.1 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PhaC_N PF07167.8 ABX12887.1 - 3.6e-13 49.3 0.1 7.8e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Abhydrolase_1 PF00561.15 ABX12887.1 - 2.4e-10 40.3 0.0 6.2e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ABX12887.1 - 3.3e-08 33.6 0.0 5.3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3141 PF11339.3 ABX12887.1 - 1.2e-07 30.4 0.0 2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3141) Abhydrolase_5 PF12695.2 ABX12887.1 - 2.9e-07 30.3 0.0 1.2e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ABX12887.1 - 0.00028 20.2 0.0 0.0028 16.9 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family PHB_depo_C PF06850.6 ABX12887.1 - 0.00099 18.3 0.0 0.0056 15.9 0.0 2.2 1 1 0 1 1 1 1 PHB de-polymerase C-terminus BAAT_C PF08840.6 ABX12887.1 - 0.0023 17.6 0.0 0.0056 16.4 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.9 ABX12887.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase AATF-Che1 PF13339.1 ABX12888.1 - 0.1 12.7 1.5 0.16 12.1 1.0 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor XPC-binding PF09280.6 ABX12888.1 - 0.15 11.5 0.8 1.7 8.1 0.5 2.4 1 1 0 1 1 1 0 XPC-binding domain DUF2937 PF11157.3 ABX12888.1 - 0.27 10.5 2.6 6.1 6.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) STAT_int PF02865.12 ABX12888.1 - 0.38 10.7 2.9 0.9 9.5 1.7 1.8 1 1 1 2 2 2 0 STAT protein, protein interaction domain Fib_alpha PF08702.5 ABX12888.1 - 0.54 10.3 5.6 2.2 8.4 0.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3452 PF11934.3 ABX12888.1 - 0.6 9.4 4.3 3.6 6.8 0.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3452) Translin PF01997.11 ABX12888.1 - 1.1 8.7 4.3 5.7 6.4 0.2 2.1 2 0 0 2 2 2 0 Translin family DUF4473 PF14747.1 ABX12888.1 - 2.5 8.3 6.5 5.4 7.3 0.6 2.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4473) DUF4359 PF14271.1 ABX12888.1 - 2.6 8.4 6.2 9.5 6.6 0.6 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4359) Antitoxin-MazE PF04014.13 ABX12889.1 - 7.2e-05 22.4 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 Antidote-toxin recognition MazE DUF148 PF02520.12 ABX12889.1 - 0.0098 15.6 0.6 0.016 15.0 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF148 MraZ PF02381.13 ABX12889.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 MraZ protein CotJB PF12652.2 ABX12889.1 - 0.19 11.7 0.8 1.5 8.9 0.0 2.0 1 1 1 2 2 2 0 CotJB protein Abhydrolase_6 PF12697.2 ABX12890.1 - 5e-35 121.4 0.0 5.8e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ABX12890.1 - 3.9e-22 78.9 0.0 1.6e-21 76.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ABX12890.1 - 4.9e-17 62.0 0.0 1.8e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ABX12890.1 - 5.3e-06 26.2 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 ABX12890.1 - 0.00015 21.2 0.0 0.21 11.0 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 ABX12890.1 - 0.004 16.7 0.0 0.1 12.2 0.0 2.4 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_4 PF08386.5 ABX12890.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.9 ABX12890.1 - 0.019 13.4 0.0 0.03 12.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family DLH PF01738.13 ABX12890.1 - 0.082 12.1 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 ABX12890.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PMSR PF01625.16 ABX12891.1 - 1.2e-65 220.1 0.4 1.5e-65 219.8 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Methyltransf_11 PF08241.7 ABX12893.1 - 1.3e-10 41.5 0.0 2.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ABX12893.1 - 7e-06 25.8 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ABX12893.1 - 1.2e-05 24.9 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ABX12893.1 - 0.0018 18.6 0.0 0.0035 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ABX12893.1 - 0.013 15.8 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 ABX12893.1 - 0.11 11.5 0.0 0.34 9.9 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Tweety PF04906.8 ABX12894.1 - 0.27 9.6 4.1 0.92 7.8 0.0 2.5 2 0 0 2 2 2 0 Tweety COG6 PF06419.6 ABX12895.1 - 0.00027 19.2 2.8 0.11 10.6 0.2 2.2 2 0 0 2 2 2 2 Conserved oligomeric complex COG6 CorA PF01544.13 ABX12895.1 - 0.00084 18.4 1.3 0.084 11.8 0.0 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein ATG16 PF08614.6 ABX12895.1 - 0.0014 18.5 4.1 0.39 10.5 0.5 2.4 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) Tropomyosin PF00261.15 ABX12895.1 - 0.0031 16.6 8.8 0.45 9.5 2.5 2.4 2 0 0 2 2 2 2 Tropomyosin IncA PF04156.9 ABX12895.1 - 0.0036 16.9 10.4 0.36 10.3 0.1 2.3 2 0 0 2 2 2 2 IncA protein DUF4140 PF13600.1 ABX12895.1 - 0.0049 17.2 6.4 0.27 11.7 0.1 3.1 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF2046 PF09755.4 ABX12895.1 - 0.01 14.7 5.8 0.01 14.7 4.0 2.7 3 1 0 3 3 2 0 Uncharacterized conserved protein H4 (DUF2046) Prefoldin_2 PF01920.15 ABX12895.1 - 0.014 15.1 19.6 0.081 12.6 2.2 4.7 5 0 0 5 5 5 0 Prefoldin subunit ADIP PF11559.3 ABX12895.1 - 0.018 14.9 10.9 1 9.2 4.2 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 ABX12895.1 - 0.03 14.2 9.6 1.2 9.0 1.7 4.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 ABX12895.1 - 0.033 13.1 11.2 1.1 8.1 0.1 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 ABX12895.1 - 0.036 13.7 14.0 0.29 10.7 0.1 2.8 3 0 0 3 3 3 0 Mnd1 family Spectrin PF00435.16 ABX12895.1 - 0.058 13.6 6.2 0.88 9.8 2.3 2.6 2 0 0 2 2 2 0 Spectrin repeat DUF1664 PF07889.7 ABX12895.1 - 0.072 12.8 6.0 1.6 8.5 1.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 ABX12895.1 - 0.08 13.2 10.6 2.3 8.5 1.7 3.8 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.7 ABX12895.1 - 0.083 11.0 9.2 0.071 11.2 3.5 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Apolipoprotein PF01442.13 ABX12895.1 - 0.094 12.2 6.3 1.2 8.6 1.8 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Seryl_tRNA_N PF02403.17 ABX12895.1 - 0.11 12.5 21.4 4.2 7.4 0.1 4.3 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Vps51 PF08700.6 ABX12895.1 - 0.11 12.3 8.2 0.37 10.6 0.7 3.8 3 0 0 3 3 3 0 Vps51/Vps67 AKNA PF12443.3 ABX12895.1 - 0.13 12.2 7.7 3.2 7.8 1.1 3.2 2 1 0 2 2 2 0 AT-hook-containing transcription factor Erp_C PF06780.6 ABX12895.1 - 0.15 11.9 9.9 0.53 10.1 0.1 2.7 2 0 0 2 2 2 0 Erp protein C-terminus TPR_MLP1_2 PF07926.7 ABX12895.1 - 0.15 11.7 17.1 0.28 10.9 4.1 3.0 3 1 0 3 3 2 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.4 ABX12895.1 - 0.16 10.1 11.0 0.0072 14.6 1.8 2.0 2 0 0 2 2 2 0 Transmembrane protein Lzipper-MIP1 PF14389.1 ABX12895.1 - 0.18 11.9 11.3 39 4.4 0.1 4.4 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 V_ATPase_I PF01496.14 ABX12895.1 - 0.23 9.2 5.4 1.2 6.8 1.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Med9 PF07544.8 ABX12895.1 - 0.23 11.2 14.4 2 8.1 1.4 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Fungal_trans_2 PF11951.3 ABX12895.1 - 0.33 9.5 1.8 5 5.6 0.4 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain FlxA PF14282.1 ABX12895.1 - 0.35 10.8 21.4 2.9 7.8 3.3 2.9 2 1 0 2 2 2 0 FlxA-like protein Takusan PF04822.8 ABX12895.1 - 0.4 10.4 8.9 0.062 13.0 3.1 2.0 2 0 0 2 2 1 0 Takusan CCDC-167 PF15188.1 ABX12895.1 - 0.43 10.5 8.5 2.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Tropomyosin_1 PF12718.2 ABX12895.1 - 0.5 10.2 14.9 0.51 10.1 4.7 2.7 3 0 0 3 3 2 0 Tropomyosin like DivIC PF04977.10 ABX12895.1 - 0.53 9.7 8.8 8 6.0 1.6 3.6 3 0 0 3 3 3 0 Septum formation initiator DUF2203 PF09969.4 ABX12895.1 - 0.56 10.4 6.5 6.2 7.0 1.3 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF4094 PF13334.1 ABX12895.1 - 0.57 10.6 10.2 0.2 12.0 0.4 3.4 4 0 0 4 4 2 0 Domain of unknown function (DUF4094) TBPIP PF07106.8 ABX12895.1 - 0.62 9.5 20.9 0.12 11.8 6.0 2.8 3 1 0 3 3 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2802 PF10975.3 ABX12895.1 - 0.68 9.7 5.6 19 5.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) TMPIT PF07851.8 ABX12895.1 - 0.86 8.6 7.5 3.1 6.7 2.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein Cob_adeno_trans PF01923.13 ABX12895.1 - 0.87 9.3 3.6 3.7 7.3 0.5 2.6 2 1 1 3 3 2 0 Cobalamin adenosyltransferase Gon7 PF08738.5 ABX12895.1 - 0.9 9.5 5.5 1.6 8.7 0.3 3.0 2 1 0 2 2 2 0 Gon7 family Cytochrom_B562 PF07361.6 ABX12895.1 - 1.1 9.6 5.2 5 7.5 0.0 2.9 2 1 0 2 2 2 0 Cytochrome b562 Sec8_exocyst PF04048.9 ABX12895.1 - 1.2 8.8 10.4 3.6 7.2 2.2 2.8 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Uds1 PF15456.1 ABX12895.1 - 1.2 9.1 14.2 0.6 10.1 2.1 3.7 4 1 0 4 4 3 0 Up-regulated During Septation Syntaxin-6_N PF09177.6 ABX12895.1 - 1.3 9.5 7.4 5.7 7.4 0.3 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF342 PF03961.8 ABX12895.1 - 1.3 7.3 14.1 1.4 7.2 3.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF342) Spc24 PF08286.6 ABX12895.1 - 1.6 8.4 14.5 0.88 9.2 4.4 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 APG6 PF04111.7 ABX12895.1 - 2.1 7.3 9.7 2.3 7.1 2.6 2.5 3 0 0 3 3 2 0 Autophagy protein Apg6 Mitofilin PF09731.4 ABX12895.1 - 2.1 6.8 15.8 0.075 11.6 3.6 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Spc7 PF08317.6 ABX12895.1 - 2.3 6.8 14.5 1.8 7.1 3.7 2.6 3 0 0 3 3 2 0 Spc7 kinetochore protein Allexi_40kDa PF05549.6 ABX12895.1 - 2.6 7.2 11.8 5.6 6.1 0.5 2.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF972 PF06156.8 ABX12895.1 - 3.3 8.0 9.3 6.1 7.2 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 ABX12895.1 - 3.7 7.9 8.3 21 5.5 0.8 3.6 2 1 1 3 3 3 0 SlyX AATF-Che1 PF13339.1 ABX12895.1 - 5.1 7.2 12.7 1.1 9.4 3.1 2.9 3 0 0 3 3 2 0 Apoptosis antagonizing transcription factor COG2 PF06148.6 ABX12895.1 - 9.2 6.1 9.4 19 5.1 1.4 3.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Lge1 PF11488.3 ABX12895.1 - 9.6 6.4 9.8 5.2 7.3 1.2 3.9 3 1 0 3 3 3 0 Transcriptional regulatory protein LGE1 Sigma70_r4_2 PF08281.7 ABX12896.1 - 0.0017 17.7 0.1 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.1 ABX12896.1 - 0.0024 17.2 2.5 0.0089 15.3 0.2 2.9 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.16 ABX12897.1 - 1.9e-13 49.9 0.0 2.2e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 AsnC family ACT_4 PF13291.1 ABX12897.1 - 0.0043 17.3 0.2 0.027 14.8 0.1 1.9 1 1 1 2 2 2 1 ACT domain FGase PF05013.7 ABX12899.1 - 8.4e-48 163.1 0.0 9.6e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase G_glu_transpept PF01019.16 ABX12900.1 - 1.3e-107 360.4 0.0 1.5e-107 360.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Ion_trans PF00520.26 ABX12901.1 - 9e-21 74.0 14.1 9e-21 74.0 9.7 1.7 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 ABX12901.1 - 9.7e-13 47.6 6.6 9.7e-13 47.6 4.6 2.4 2 0 0 2 2 2 1 Ion channel Zn-ribbon_8 PF09723.5 ABX12901.1 - 0.054 13.4 0.2 0.099 12.6 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 ABX12901.1 - 0.091 12.2 0.4 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain PKD_channel PF08016.7 ABX12901.1 - 0.3 9.4 5.7 0.031 12.7 0.5 1.7 1 1 1 2 2 2 0 Polycystin cation channel CorA PF01544.13 ABX12902.1 - 4.6e-70 235.9 7.9 4.6e-70 235.9 5.5 2.5 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein YbjQ_1 PF01906.12 ABX12902.1 - 0.019 15.3 0.1 0.054 13.9 0.1 1.8 1 0 0 1 1 1 0 Putative heavy-metal-binding Herpes_UL92 PF03048.9 ABX12902.1 - 0.049 13.1 0.4 0.23 11.0 0.1 2.1 1 1 1 2 2 2 0 UL92 family DUF454 PF04304.8 ABX12902.1 - 0.12 12.4 0.0 0.12 12.4 0.0 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF454) T2SF PF00482.18 ABX12902.1 - 0.51 10.2 0.0 0.51 10.2 0.0 4.2 5 0 0 5 5 5 0 Type II secretion system (T2SS), protein F DUF1049 PF06305.6 ABX12902.1 - 1.8 8.0 4.4 7.2 6.1 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF21 PF01595.15 ABX12903.1 - 4.1e-54 182.6 0.1 5.6e-54 182.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 ABX12903.1 - 5.2e-20 70.9 0.9 1.4e-09 37.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain CorC_HlyC PF03471.12 ABX12903.1 - 7.4e-18 64.1 1.1 1.6e-17 63.0 0.1 2.0 2 0 0 2 2 2 1 Transporter associated domain Dala_Dala_lig_C PF07478.8 ABX12904.1 - 1.3e-32 112.8 0.0 2.4e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 ABX12904.1 - 9.8e-19 67.8 0.0 3.1e-18 66.1 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 ABX12904.1 - 6.3e-11 42.4 0.2 1.2e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ABX12904.1 - 1.4e-09 37.2 0.0 6.4e-09 35.0 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 ABX12904.1 - 1.3e-07 31.1 0.0 2.9e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Peptidase_M20 PF01546.23 ABX12904.1 - 3e-07 30.1 0.0 5.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 RimK PF08443.6 ABX12904.1 - 1.1e-06 28.2 0.5 2.3e-05 23.9 0.4 2.4 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 ABX12904.1 - 5.4e-05 22.8 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Dala_Dala_lig_N PF01820.16 ABX12904.1 - 0.031 14.6 0.3 0.72 10.1 0.2 2.7 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus Ycf1 PF05758.7 ABX12905.1 - 0.00032 18.5 1.9 0.00035 18.4 1.3 1.1 1 0 0 1 1 1 1 Ycf1 Apolipoprotein PF01442.13 ABX12905.1 - 0.00038 20.0 9.3 0.00038 20.0 6.5 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prominin PF05478.6 ABX12905.1 - 0.016 12.7 8.8 0.036 11.6 6.1 1.5 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.7 ABX12905.1 - 0.06 13.1 8.8 0.13 12.0 6.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2678 PF10856.3 ABX12905.1 - 0.073 12.8 8.3 0.073 12.8 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Z1 PF10593.4 ABX12905.1 - 0.29 10.3 6.2 0.55 9.4 4.3 1.4 1 0 0 1 1 1 0 Z1 domain DNA_primase_lrg PF04104.9 ABX12905.1 - 0.55 9.4 8.1 0.92 8.7 5.6 1.3 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Baculo_PEP_C PF04513.7 ABX12905.1 - 0.57 9.9 2.7 1.3 8.8 1.9 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2317 PF10079.4 ABX12905.1 - 0.71 8.4 14.1 0.99 7.9 9.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Phasin PF05597.6 ABX12905.1 - 1.9 8.2 18.5 2.3 8.0 5.0 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) OmpH PF03938.9 ABX12905.1 - 2 8.3 20.0 3.3 7.6 13.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF885 PF05960.6 ABX12905.1 - 2.7 7.0 6.6 3.3 6.7 4.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) ISG65-75 PF11727.3 ABX12905.1 - 3.4 6.6 20.7 4.6 6.2 14.3 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Mit_KHE1 PF10173.4 ABX12905.1 - 3.4 7.4 5.2 7 6.4 3.6 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Mitofilin PF09731.4 ABX12905.1 - 5.5 5.5 24.2 8.4 4.9 16.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein IncA PF04156.9 ABX12905.1 - 6.3 6.3 14.4 0.21 11.1 5.4 2.0 2 0 0 2 2 2 0 IncA protein zf-H2C2_5 PF13909.1 ABX12906.1 - 0.0019 18.2 1.1 0.0034 17.5 0.8 1.4 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-Di19 PF05605.7 ABX12906.1 - 0.0055 16.7 0.3 0.0083 16.2 0.2 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF996 PF06195.8 ABX12906.1 - 0.0062 16.5 0.4 0.0079 16.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF996) Sensor PF13796.1 ABX12906.1 - 0.0099 15.4 2.9 0.012 15.2 2.0 1.0 1 0 0 1 1 1 1 Putative sensor Permease PF02405.11 ABX12906.1 - 0.016 14.6 1.0 0.021 14.3 0.7 1.1 1 0 0 1 1 1 0 Permease DUF3816 PF12822.2 ABX12906.1 - 0.036 13.9 0.4 0.036 13.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) Colicin_V PF02674.11 ABX12906.1 - 0.052 13.4 3.2 0.066 13.0 2.2 1.1 1 0 0 1 1 1 0 Colicin V production protein ABC_membrane_2 PF06472.10 ABX12906.1 - 0.089 11.8 0.1 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 MoeZ_MoeB PF05237.8 ABX12906.1 - 0.14 11.7 0.5 0.42 10.2 0.0 1.9 2 1 0 2 2 2 0 MoeZ/MoeB domain FtsX PF02687.16 ABX12906.1 - 0.34 10.6 3.7 0.48 10.1 2.6 1.1 1 0 0 1 1 1 0 FtsX-like permease family DUF4235 PF14019.1 ABX12906.1 - 0.51 10.2 7.8 6 6.7 5.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4235) MARVEL PF01284.18 ABX12906.1 - 0.67 9.7 4.0 2.4 7.9 2.6 1.8 1 1 1 2 2 2 0 Membrane-associating domain TM_helix PF05552.7 ABX12906.1 - 1.1 8.9 5.5 0.37 10.5 0.7 2.0 2 0 0 2 2 2 0 Conserved TM helix Flp_Fap PF04964.9 ABX12906.1 - 4.5 6.9 10.0 0.66 9.6 2.1 2.3 2 0 0 2 2 2 0 Flp/Fap pilin component Nitroreductase PF00881.19 ABX12907.1 - 5.8e-29 101.0 0.0 8.9e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family eIF-1a PF01176.14 ABX12907.1 - 0.018 14.4 0.2 0.065 12.6 0.1 2.0 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 Usp PF00582.21 ABX12908.1 - 3.5e-27 95.3 0.3 5e-27 94.8 0.2 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF2362 PF10154.4 ABX12908.1 - 0.011 14.4 0.2 0.011 14.3 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) DUF1975 PF09318.5 ABX12908.1 - 0.032 13.8 0.1 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1975) Phage_Gp19 PF09355.5 ABX12908.1 - 0.16 11.8 1.9 0.21 11.4 1.0 1.4 1 1 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 HTH_20 PF12840.2 ABX12910.1 - 7.4e-05 22.4 0.1 0.00021 21.0 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.2 ABX12910.1 - 0.0011 18.5 0.1 0.061 13.0 0.0 2.3 2 0 0 2 2 2 1 MarR family DUF4423 PF14394.1 ABX12910.1 - 0.0018 17.8 0.0 0.0095 15.4 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4423) DUF2250 PF10007.4 ABX12910.1 - 0.0032 17.3 0.9 0.67 9.8 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.14 ABX12910.1 - 0.0067 16.1 0.1 2.1 8.1 0.0 2.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.1 ABX12910.1 - 0.022 14.5 0.2 0.39 10.5 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix Mrr_N PF14338.1 ABX12910.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Mrr N-terminal domain HTH_24 PF13412.1 ABX12910.1 - 0.051 12.9 0.3 0.31 10.4 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 ABX12910.1 - 0.086 12.5 0.7 6.7 6.5 0.0 2.4 2 0 0 2 2 2 0 MarR family DUF1724 PF08350.5 ABX12910.1 - 0.1 12.1 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) DUF4377 PF14302.1 ABX12911.1 - 7e-27 93.1 0.3 1.6e-26 91.9 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4377) Kazal_1 PF00050.16 ABX12911.1 - 3.8e-10 39.6 0.1 1.4e-09 37.7 0.1 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 ABX12911.1 - 2.3e-07 30.6 1.2 5.8e-07 29.3 0.9 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DUF2127 PF09900.4 ABX12912.1 - 0.13 12.2 15.8 0.094 12.7 5.7 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2127) L_HGMIC_fpl PF10242.4 ABX12912.1 - 6.8 6.6 10.6 0.61 10.0 3.7 1.7 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein BCLP PF12304.3 ABX12912.1 - 9.1 5.6 13.6 20 4.5 9.3 1.6 1 1 1 2 2 2 0 Beta-casein like protein Aminotran_3 PF00202.16 ABX12913.1 - 2.3e-54 184.5 0.0 2.9e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF3127 PF11325.3 ABX12914.1 - 0.12 12.3 0.1 0.17 11.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3127) TPR_11 PF13414.1 ABX12915.1 - 6.7e-48 160.2 20.6 1.1e-14 53.8 0.7 4.5 1 1 5 6 6 6 6 TPR repeat TPR_2 PF07719.12 ABX12915.1 - 2e-37 124.0 4.4 2.2e-05 24.0 0.0 7.2 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 ABX12915.1 - 1.3e-31 106.8 18.0 3.1e-07 29.7 0.0 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 ABX12915.1 - 9.7e-31 105.7 1.1 8.1e-08 32.7 0.0 5.0 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 ABX12915.1 - 2.5e-28 95.8 9.9 1.2e-05 25.0 0.2 6.5 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 ABX12915.1 - 1e-24 86.2 14.0 1.6e-09 37.5 0.4 4.4 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 ABX12915.1 - 1.2e-24 84.4 0.0 0.025 15.1 0.1 7.1 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.1 ABX12915.1 - 1.9e-22 78.1 3.5 0.035 14.5 0.1 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 ABX12915.1 - 4.9e-20 71.6 8.6 3.6e-06 27.1 0.2 4.8 1 1 4 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 ABX12915.1 - 1.1e-19 68.6 14.8 6.7e-05 22.3 0.0 7.2 6 1 1 7 7 7 6 Tetratricopeptide repeat Apc3 PF12895.2 ABX12915.1 - 1.8e-13 50.4 8.8 0.00019 21.4 0.2 3.3 1 1 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ABX12915.1 - 3.2e-13 49.3 0.0 4.9e-05 23.1 0.0 4.3 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 ABX12915.1 - 2.3e-11 42.5 2.8 0.00097 18.7 0.0 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.3 ABX12915.1 - 1.2e-08 34.2 7.4 2e-05 23.5 0.4 3.1 1 1 1 3 3 3 2 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 ABX12915.1 - 3.4e-07 30.0 4.6 0.2 11.5 0.0 5.9 4 2 2 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.9 ABX12915.1 - 8.1e-07 28.5 4.9 0.023 13.8 0.1 3.9 1 1 4 5 5 5 3 Coatomer epsilon subunit TPR_20 PF14561.1 ABX12915.1 - 1.1e-05 25.4 5.2 0.3 11.2 0.1 4.4 1 1 5 6 6 6 2 Tetratricopeptide repeat MIT PF04212.13 ABX12915.1 - 1.2e-05 25.0 11.0 2.5 8.0 0.1 6.1 4 2 2 6 6 6 2 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 ABX12915.1 - 9.6e-05 22.1 4.0 3 7.9 0.5 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 ABX12915.1 - 0.0002 21.1 0.3 2.7 7.8 0.0 4.2 1 1 3 5 5 5 1 Rapsyn N-terminal myristoylation and linker region TPR_5 PF12688.2 ABX12915.1 - 0.0044 17.0 0.3 0.53 10.3 0.0 3.2 1 1 1 3 3 3 1 Tetratrico peptide repeat TOM20_plant PF06552.7 ABX12915.1 - 0.0053 16.3 4.1 0.48 10.0 0.2 3.7 1 1 2 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 Thioredoxin_6 PF13848.1 ABX12915.1 - 0.0054 16.5 0.9 0.038 13.7 0.1 2.5 2 1 0 3 3 3 1 Thioredoxin-like domain DUF3452 PF11934.3 ABX12915.1 - 0.011 15.0 0.8 0.19 11.0 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3452) Apc5 PF12862.2 ABX12915.1 - 0.015 15.0 0.7 0.067 13.0 0.1 2.5 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 ChAPs PF09295.5 ABX12915.1 - 0.017 13.9 1.6 0.11 11.1 0.2 2.0 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 ABX12915.1 - 0.069 13.6 0.0 8.5 7.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 ABX12915.1 - 0.16 11.7 9.0 5.7 6.8 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat OSCP PF00213.13 ABX12915.1 - 0.5 10.2 4.8 10 5.9 0.6 3.2 2 1 2 4 4 4 0 ATP synthase delta (OSCP) subunit PPR PF01535.15 ABX12915.1 - 0.84 9.7 6.2 15 5.8 0.0 5.3 7 0 0 7 7 6 0 PPR repeat Toprim_Crpt PF13342.1 ABX12916.1 - 0.0022 17.5 0.2 0.0076 15.8 0.2 1.9 1 0 0 1 1 1 1 C-terminal repeat of topoisomerase SHOCT PF09851.4 ABX12917.1 - 2.9e-08 32.8 3.9 6.6e-08 31.7 2.7 1.7 1 0 0 1 1 1 1 Short C-terminal domain DUF2680 PF10925.3 ABX12917.1 - 0.16 11.8 3.9 0.21 11.4 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2680) DUF2052 PF09747.4 ABX12917.1 - 0.26 11.2 3.0 0.31 10.9 2.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DivIVA PF05103.8 ABX12917.1 - 0.41 10.6 7.2 0.76 9.8 5.0 1.5 1 1 0 1 1 1 0 DivIVA protein ATP-synt_B PF00430.13 ABX12917.1 - 2.7 7.8 11.2 7.8 6.3 7.7 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) POX PF07526.6 ABX12917.1 - 4.6 7.4 6.9 10 6.3 4.8 1.5 1 1 0 1 1 1 0 Associated with HOX Cupin_2 PF07883.6 ABX12918.1 - 1.7e-07 30.6 0.2 7.9e-07 28.4 0.1 1.9 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 ABX12918.1 - 2.5e-06 27.0 0.0 3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Cupin Auxin_BP PF02041.11 ABX12918.1 - 2.2e-05 23.9 0.1 2.7e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Auxin binding protein Cupin_8 PF13621.1 ABX12918.1 - 0.00055 19.5 0.1 0.0022 17.5 0.0 1.6 1 1 1 2 2 2 1 Cupin-like domain AraC_binding PF02311.14 ABX12918.1 - 0.024 14.3 0.1 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 AraC-like ligand binding domain FHA PF00498.21 ABX12918.1 - 0.077 13.1 0.3 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 FHA domain DTHCT PF08070.6 ABX12918.1 - 0.17 12.5 0.2 0.17 12.5 0.1 2.5 3 1 0 3 3 3 0 DTHCT (NUC029) region Cupin_2 PF07883.6 ABX12919.1 - 7.2e-15 54.2 0.0 1.8e-14 52.9 0.0 1.6 2 0 0 2 2 2 1 Cupin domain MannoseP_isomer PF01050.13 ABX12919.1 - 6.8e-09 35.4 0.0 8.1e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Ectoine_synth PF06339.7 ABX12919.1 - 2.6e-05 24.1 0.0 3.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ectoine synthase Cupin_1 PF00190.17 ABX12919.1 - 3.9e-05 23.1 0.0 7.2e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Cupin AraC_binding PF02311.14 ABX12919.1 - 6.3e-05 22.6 0.0 8.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 ABX12919.1 - 0.00023 20.4 0.0 0.00036 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 ABX12919.1 - 0.0026 17.3 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ GPI PF06560.6 ABX12919.1 - 0.0027 16.7 0.0 0.0048 15.9 0.0 1.4 1 1 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) CENP-C_C PF11699.3 ABX12919.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like DnaJ PF00226.26 ABX12920.1 - 2.7e-16 59.0 3.8 5.9e-16 57.9 2.6 1.5 1 0 0 1 1 1 1 DnaJ domain Fer4_15 PF13459.1 ABX12920.1 - 1.5e-10 41.4 2.4 3.7e-10 40.2 1.7 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.1 ABX12920.1 - 2.6e-09 37.3 2.2 2.6e-09 37.3 1.5 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_19 PF06902.6 ABX12920.1 - 3.1e-05 23.6 4.1 4.1e-05 23.3 0.6 2.4 2 0 0 2 2 2 1 Divergent 4Fe-4S mono-cluster RPT PF13446.1 ABX12920.1 - 0.003 16.9 0.1 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 A repeated domain in UCH-protein NUMOD1 PF07453.8 ABX12920.1 - 0.012 15.4 1.4 0.25 11.2 0.2 2.5 2 0 0 2 2 2 0 NUMOD1 domain Fer4_7 PF12838.2 ABX12920.1 - 0.057 13.8 1.1 0.85 10.0 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.22 ABX12920.1 - 0.27 10.8 10.2 0.76 9.4 4.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.1 ABX12920.1 - 0.32 11.4 0.1 0.32 11.4 0.1 3.3 3 1 0 3 3 3 0 4Fe-4S dicluster domain DUF2315 PF10231.4 ABX12920.1 - 9.9 6.0 14.7 0.23 11.3 1.5 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2315) HIT PF01230.18 ABX12921.1 - 5.8e-23 81.2 1.6 7.4e-23 80.9 1.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 ABX12921.1 - 1.3e-13 51.1 1.2 1.6e-13 50.8 0.8 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 ABX12921.1 - 1.8e-05 24.3 0.9 2.1e-05 24.1 0.6 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.12 ABX12921.1 - 0.01 15.4 0.7 0.014 14.9 0.5 1.3 1 1 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4319 PF14203.1 ABX12921.1 - 0.079 12.5 0.2 0.3 10.6 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4319) ATP1G1_PLM_MAT8 PF02038.11 ABX12922.1 - 0.077 12.0 1.0 0.12 11.4 0.7 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family zf-BED PF02892.10 ABX12923.1 - 0.00085 19.0 1.2 0.0012 18.5 0.8 1.3 1 0 0 1 1 1 1 BED zinc finger zf-C2H2 PF00096.21 ABX12923.1 - 0.0042 17.3 1.4 0.0063 16.7 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 ABX12923.1 - 0.015 15.4 0.1 0.015 15.3 0.1 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF4553 PF15090.1 ABX12923.1 - 0.085 11.8 0.2 0.093 11.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) zf-FCS PF06467.9 ABX12923.1 - 0.12 12.0 0.3 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_4 PF13894.1 ABX12923.1 - 0.21 12.0 0.6 0.31 11.4 0.4 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 ABX12923.1 - 1 9.7 4.6 3.2 8.1 3.2 1.8 1 1 0 1 1 1 0 C2H2-type zinc-finger domain 3HCDH_N PF02737.13 ABX12924.1 - 1.5e-65 220.2 0.3 2.5e-65 219.4 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 ABX12924.1 - 1.3e-34 118.5 0.1 1.7e-24 86.0 0.0 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 ABX12924.1 - 7.6e-08 32.2 0.1 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 ABX12924.1 - 2.2e-05 24.3 0.0 4.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ABX12924.1 - 0.002 18.4 1.1 0.01 16.2 0.8 2.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF4078 PF13300.1 ABX12924.1 - 0.022 14.8 0.3 0.04 14.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) UDPG_MGDP_dh_N PF03721.9 ABX12924.1 - 0.043 13.1 0.1 0.083 12.2 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.7 ABX12924.1 - 1.3 8.3 4.5 52 3.1 3.1 2.3 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain SapB_1 PF05184.10 ABX12925.1 - 0.01 15.6 0.4 0.043 13.6 0.0 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 GP41 PF00517.12 ABX12925.1 - 0.028 13.9 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Retroviral envelope protein DUF1250 PF06855.7 ABX12925.1 - 0.089 12.3 0.2 0.18 11.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1250) Tox-PL-2 PF15643.1 ABX12925.1 - 0.12 12.3 0.1 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Papain fold toxin 2 Lysine_decarbox PF03641.9 ABX12926.1 - 2.5e-06 27.3 0.0 6.9e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Possible lysine decarboxylase DNA_processg_A PF02481.10 ABX12926.1 - 0.00049 19.0 0.4 0.0049 15.7 0.1 2.2 2 0 0 2 2 2 1 DNA recombination-mediator protein A DAGK_cat PF00781.19 ABX12926.1 - 0.0008 18.8 1.4 0.082 12.3 0.0 2.2 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain Ribosomal_S14 PF00253.16 ABX12927.1 - 0.00024 20.4 5.0 0.0072 15.6 0.6 3.1 3 1 0 3 3 3 2 Ribosomal protein S14p/S29e zf-C4pol PF14260.1 ABX12927.1 - 0.008 16.1 8.9 0.22 11.5 0.4 3.3 2 1 1 3 3 3 1 C4-type zinc-finger of DNA polymerase delta DUF4428 PF14471.1 ABX12927.1 - 0.013 15.2 3.0 0.013 15.2 2.1 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4428) zf-CHY PF05495.7 ABX12927.1 - 0.04 14.0 17.1 0.27 11.4 3.8 3.1 1 1 2 3 3 3 0 CHY zinc finger NOB1_Zn_bind PF08772.6 ABX12927.1 - 0.043 13.6 1.9 0.043 13.6 1.3 3.3 2 2 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 ABX12927.1 - 0.075 12.5 0.1 0.075 12.5 0.0 2.7 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain FYVE PF01363.16 ABX12927.1 - 0.16 11.8 16.5 2.7 7.9 0.4 3.3 1 1 1 2 2 2 0 FYVE zinc finger Cytochrome_C7 PF14522.1 ABX12927.1 - 0.33 10.6 17.6 0.17 11.5 3.6 2.9 1 1 2 3 3 3 0 Cytochrome c7 C1_1 PF00130.17 ABX12927.1 - 0.76 9.5 16.6 0.37 10.5 0.9 3.3 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-dskA_traR PF01258.12 ABX12927.1 - 1.4 8.7 0.1 1.4 8.7 0.1 4.5 5 1 1 6 6 6 0 Prokaryotic dksA/traR C4-type zinc finger Cytochrom_c3_2 PF14537.1 ABX12927.1 - 9.2 6.6 17.1 2.5e+02 2.1 11.9 2.9 1 1 0 1 1 1 0 Cytochrome c3 DNA_RNApol_7kD PF03604.8 ABX12928.1 - 6.3e-05 22.3 1.2 0.00011 21.6 0.8 1.4 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-HIT PF04438.11 ABX12928.1 - 0.26 10.9 2.3 0.76 9.4 1.5 1.8 1 1 1 2 2 2 0 HIT zinc finger Ribosomal_S10 PF00338.17 ABX12929.1 - 5.8e-26 90.1 0.0 6.4e-26 90.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GTP_EFTU PF00009.22 ABX12930.1 - 1.3e-48 164.9 0.1 1.8e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ABX12930.1 - 2.5e-31 107.7 0.5 9.9e-31 105.8 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ABX12930.1 - 6.5e-18 64.6 1.0 1.7e-17 63.2 0.7 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 ABX12930.1 - 7.1e-07 28.7 0.6 1.7e-06 27.5 0.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 ABX12930.1 - 0.0056 16.6 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FBPase_3 PF01950.11 ABX12931.1 - 6e-159 528.8 0.1 6.8e-159 528.6 0.1 1.0 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase YrhC PF14143.1 ABX12932.1 - 0.12 12.3 1.4 0.24 11.3 1.0 1.6 1 0 0 1 1 1 0 YrhC-like protein DNA_ligase_A_M PF01068.16 ABX12933.1 - 2e-56 190.5 1.2 4.5e-56 189.4 0.8 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 ABX12933.1 - 4.6e-52 176.3 2.1 8.1e-52 175.5 1.5 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 ABX12933.1 - 5.6e-23 81.1 0.0 1.1e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 ABX12933.1 - 0.044 13.4 0.1 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 DNA ligase OB-like domain PhoU_div PF01865.11 ABX12934.1 - 1.2e-19 70.3 10.8 1.4e-19 70.1 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 PhoU PF01895.14 ABX12934.1 - 0.0092 16.4 13.8 0.03 14.7 2.5 3.0 2 2 1 3 3 3 2 PhoU domain DUF677 PF05055.7 ABX12934.1 - 0.014 14.1 0.8 0.014 14.1 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF677) LXG PF04740.7 ABX12934.1 - 0.023 14.5 7.0 0.07 12.9 0.3 2.5 1 1 1 2 2 2 0 LXG domain of WXG superfamily ISAV_HA PF06215.6 ABX12934.1 - 0.024 12.9 0.0 0.037 12.3 0.0 1.3 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin DUF458 PF04308.7 ABX12934.1 - 0.045 13.4 5.2 0.28 10.8 1.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF458) MCPsignal PF00015.16 ABX12934.1 - 0.89 9.0 10.9 0.83 9.1 2.1 2.7 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain tRNA_int_endo PF01974.12 ABX12935.1 - 1.8e-27 94.9 0.0 3.1e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 ABX12935.1 - 5.4e-20 70.7 0.0 1e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain UPF0179 PF03684.8 ABX12935.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0179) fn3 PF00041.16 ABX12936.1 - 2.1e-53 178.3 8.3 4.5e-17 61.9 0.3 3.5 3 0 0 3 3 3 3 Fibronectin type III domain FHA PF00498.21 ABX12936.1 - 8.3e-05 22.6 0.0 1.8 8.7 0.0 3.6 3 0 0 3 3 3 1 FHA domain A2M_N PF01835.14 ABX12936.1 - 0.0011 19.1 0.0 0.0057 16.8 0.0 2.3 1 0 0 1 1 1 1 MG2 domain Copper-bind PF00127.15 ABX12936.1 - 0.011 16.0 0.0 0.032 14.4 0.0 1.8 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 ABX12936.1 - 0.023 14.5 0.0 0.1 12.4 0.0 2.2 1 0 0 1 1 1 0 Cupredoxin-like domain CytadhesinP1 PF12378.3 ABX12936.1 - 0.079 12.9 0.5 0.47 10.4 0.0 2.6 4 0 0 4 4 4 0 Trypsin-sensitive surface-exposed protein adh_short PF00106.20 ABX12939.1 - 1.9e-29 102.7 0.0 2.2e-22 79.7 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 ABX12939.1 - 6.8e-15 55.4 0.0 3.9e-09 36.6 0.0 3.2 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ABX12939.1 - 9.2e-15 54.7 0.0 3.9e-10 39.6 0.0 2.6 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 ABX12939.1 - 2.8e-07 30.2 0.0 3.9e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ABX12939.1 - 0.0019 17.1 0.2 0.0063 15.4 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 ABX12939.1 - 0.0035 17.4 0.3 0.046 13.8 0.1 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 ABX12939.1 - 0.017 14.7 0.3 0.044 13.4 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ABX12939.1 - 0.027 14.4 0.5 0.15 12.0 0.2 2.2 2 1 0 2 2 2 0 NADH(P)-binding BRCT PF00533.21 ABX12939.1 - 0.096 12.8 0.1 0.66 10.1 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Response_reg PF00072.19 ABX12941.1 - 5.3e-17 61.8 1.1 5.9e-17 61.6 0.7 1.0 1 0 0 1 1 1 1 Response regulator receiver domain BON PF04972.12 ABX12941.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 BON domain DUF4325 PF14213.1 ABX12941.1 - 0.11 12.1 0.1 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4325) PAS_9 PF13426.1 ABX12942.1 - 1e-14 54.7 0.2 5.4e-14 52.4 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 ABX12942.1 - 7.2e-12 45.1 0.0 1.5e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold HAMP PF00672.20 ABX12942.1 - 3.6e-11 43.0 0.0 3.6e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 HAMP domain PAS_3 PF08447.6 ABX12942.1 - 8.7e-06 25.7 0.1 2.8e-05 24.1 0.1 2.0 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 ABX12942.1 - 0.0053 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain ATP-synt_B PF00430.13 ABX12942.1 - 0.019 14.7 0.6 0.019 14.7 0.4 2.0 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) fn3 PF00041.16 ABX12943.1 - 8.8e-35 118.7 23.0 5.7e-14 52.0 3.1 4.3 4 0 0 4 4 4 3 Fibronectin type III domain NHL PF01436.16 ABX12943.1 - 2.4e-32 109.2 8.3 3.8e-07 29.7 0.0 6.6 6 0 0 6 6 6 5 NHL repeat Lactonase PF10282.4 ABX12943.1 - 6.9e-09 35.2 6.7 0.001 18.2 0.1 5.1 4 2 1 6 6 6 3 Lactonase, 7-bladed beta-propeller SGL PF08450.7 ABX12943.1 - 1.7e-06 27.5 8.6 0.047 13.0 0.0 4.5 2 2 1 4 4 4 2 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 ABX12943.1 - 2.8e-05 24.0 0.0 1.1 9.3 0.0 5.3 5 0 0 5 5 5 1 Arylesterase SusE PF14292.1 ABX12943.1 - 0.00019 21.2 12.3 0.052 13.3 3.3 4.0 4 0 0 4 4 4 2 SusE outer membrane protein Cytotoxic PF09000.5 ABX12943.1 - 0.16 11.9 0.0 29 4.7 0.0 3.0 2 1 0 2 2 2 0 Cytotoxic TauE PF01925.14 ABX12944.1 - 6.8e-49 166.4 33.9 8.5e-49 166.1 23.5 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF4131 PF13567.1 ABX12944.1 - 4.1 6.7 8.6 3.2 7.1 0.1 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF3353 PF11833.3 ABX12944.1 - 4.1 6.7 16.4 0.34 10.3 2.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3353) DUF1614 PF07758.6 ABX12945.1 - 0.028 14.1 0.2 0.061 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) PPO1_DWL PF12142.3 ABX12945.1 - 0.13 11.7 0.7 0.42 10.1 0.0 2.0 2 0 0 2 2 2 0 Polyphenol oxidase middle domain DUF192 PF02643.10 ABX12946.1 - 1.6e-28 98.5 0.0 2.4e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 Fe_dep_repress PF01325.14 ABX12949.1 - 2.3e-19 69.0 1.0 3.5e-19 68.4 0.7 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.10 ABX12949.1 - 2e-13 49.8 0.0 3.6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain HTH_24 PF13412.1 ABX12949.1 - 0.00027 20.2 0.1 0.00067 18.9 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 ABX12949.1 - 0.00029 21.0 0.0 0.0011 19.2 0.0 2.0 2 1 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.2 ABX12949.1 - 0.00034 20.2 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 ABX12949.1 - 0.00038 20.1 0.1 0.00068 19.2 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.11 ABX12949.1 - 0.00085 18.8 0.0 0.0029 17.1 0.0 1.9 3 0 0 3 3 2 1 LexA DNA binding domain DUF4423 PF14394.1 ABX12949.1 - 0.0026 17.2 0.0 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) HTH_28 PF13518.1 ABX12949.1 - 0.0042 17.0 0.0 0.058 13.4 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain MarR PF01047.17 ABX12949.1 - 0.0043 16.7 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 MarR family DUF2250 PF10007.4 ABX12949.1 - 0.0065 16.3 0.1 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) FeoC PF09012.5 ABX12949.1 - 0.028 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator PAX PF00292.13 ABX12949.1 - 0.053 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain HTH_IclR PF09339.5 ABX12949.1 - 0.054 13.0 0.4 0.094 12.3 0.0 1.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.1 ABX12949.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_12 PF08461.5 ABX12949.1 - 0.064 12.9 0.1 0.15 11.8 0.1 1.6 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain Ribosomal_S19e PF01090.14 ABX12949.1 - 0.079 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S19e HTH_34 PF13601.1 ABX12949.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_6 PF01418.12 ABX12949.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 2 1 0 2 2 2 0 Helix-turn-helix domain, rpiR family Rrf2 PF02082.15 ABX12949.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_5 PF01022.15 ABX12949.1 - 0.15 11.7 0.2 0.3 10.7 0.0 1.6 2 0 0 2 2 1 0 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.1 ABX12949.1 - 0.15 11.2 0.1 0.62 9.2 0.0 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 T2SE PF00437.15 ABX12950.1 - 3e-12 46.0 0.0 5.1e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein KH_1 PF00013.24 ABX12950.1 - 7.2e-09 35.1 0.0 7.2e-09 35.1 0.0 2.9 4 0 0 4 4 2 1 KH domain KH_3 PF13014.1 ABX12950.1 - 2.2e-07 30.3 1.1 9.1e-07 28.3 0.0 2.7 2 0 0 2 2 1 1 KH domain KH_2 PF07650.12 ABX12950.1 - 3.3e-07 29.7 0.2 1.3e-06 27.8 0.1 2.0 1 0 0 1 1 1 1 KH domain PIN PF01850.16 ABX12950.1 - 1.1e-06 28.9 0.0 2.8e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 PIN domain PIN_4 PF13638.1 ABX12950.1 - 2.5e-06 27.6 0.9 1.3e-05 25.3 0.1 2.6 2 1 0 2 2 1 1 PIN domain KH_5 PF13184.1 ABX12950.1 - 1.3e-05 24.8 2.5 1.7e-05 24.5 0.2 2.4 2 0 0 2 2 1 1 NusA-like KH domain AAA_14 PF13173.1 ABX12950.1 - 4e-05 23.5 0.0 0.00018 21.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ABX12950.1 - 0.00013 22.7 0.0 0.00043 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ABX12950.1 - 0.00024 21.4 0.1 0.027 14.7 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.1 ABX12950.1 - 0.0005 20.3 0.6 0.0024 18.1 0.0 2.4 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 ABX12950.1 - 0.00084 18.1 0.0 0.0018 17.1 0.0 1.5 1 0 0 1 1 1 1 ArgK protein AAA_28 PF13521.1 ABX12950.1 - 0.0019 18.2 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ABX12950.1 - 0.0023 17.6 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ABX12950.1 - 0.004 17.2 0.0 0.023 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ABX12950.1 - 0.0046 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ABX12950.1 - 0.0061 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 ABX12950.1 - 0.011 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.17 ABX12950.1 - 0.017 13.9 0.0 0.084 11.7 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.1 ABX12950.1 - 0.02 14.3 0.1 0.055 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 ABX12950.1 - 0.021 14.3 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 ABX12950.1 - 0.028 14.3 0.0 0.074 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 ABX12950.1 - 0.038 13.2 0.0 0.095 11.8 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 ABX12950.1 - 0.047 13.1 0.1 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 ABX12950.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 ABX12950.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 ABX12950.1 - 0.11 12.2 0.1 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PmbA_TldD PF01523.11 ABX12951.1 - 7.2e-74 248.7 0.1 8.7e-74 248.4 0.1 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase FliH PF02108.11 ABX12951.1 - 0.045 13.6 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Flagellar assembly protein FliH GxDLY PF14607.1 ABX12951.1 - 0.046 13.2 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type UDG PF03167.14 ABX12952.1 - 6.5e-36 123.0 0.0 8.3e-36 122.7 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Epimerase_2 PF02350.14 ABX12952.1 - 0.036 12.8 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Pur_DNA_glyco PF02245.11 ABX12953.1 - 2.4e-64 215.8 0.1 3e-64 215.5 0.1 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) SNARE_assoc PF09335.6 ABX12954.1 - 8e-17 61.5 1.0 8e-17 61.5 0.7 2.1 2 1 0 2 2 2 1 SNARE associated Golgi protein Apc4_WD40 PF12894.2 ABX12954.1 - 0.096 12.2 0.1 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Glycophorin_A PF01102.13 ABX12954.1 - 0.19 11.4 1.0 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Glycophorin A VKOR PF07884.9 ABX12954.1 - 7.3 6.4 6.9 1.8 8.3 0.2 2.6 3 0 0 3 3 3 0 Vitamin K epoxide reductase family DUF3591 PF12157.3 ABX12956.1 - 0.027 12.8 1.8 0.03 12.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) DUF4256 PF14066.1 ABX12956.1 - 0.054 12.9 0.2 0.065 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) Med4 PF10018.4 ABX12956.1 - 0.086 12.2 2.7 0.096 12.0 1.9 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 WPP PF13943.1 ABX12956.1 - 0.1 12.7 1.6 0.13 12.4 1.1 1.1 1 0 0 1 1 1 0 WPP domain VKG_Carbox PF05090.9 ABX12956.1 - 0.14 11.0 1.1 0.16 10.7 0.8 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase 6PF2K PF01591.13 ABX12956.1 - 0.23 10.5 4.0 0.26 10.3 2.8 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Pox_polyA_pol_N PF12630.2 ABX12956.1 - 0.32 11.0 4.3 0.51 10.4 3.0 1.5 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain CorA PF01544.13 ABX12956.1 - 0.39 9.7 3.3 0.51 9.3 2.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2392 PF10288.4 ABX12956.1 - 0.86 9.9 3.9 1.4 9.2 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2392) NOP5NT PF08156.8 ABX12956.1 - 1.7 8.8 4.3 3.4 7.9 3.0 1.5 1 0 0 1 1 1 0 NOP5NT (NUC127) domain DUF95 PF01944.12 ABX12957.1 - 2.4e-06 27.3 11.9 3.6e-06 26.7 8.2 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF95 Guanylate_cyc PF00211.15 ABX12958.1 - 2.9e-05 23.4 0.0 0.00031 20.1 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain DUF1370 PF07114.6 ABX12958.1 - 0.062 12.5 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1370) ABC_tran PF00005.22 ABX12960.1 - 5.1e-27 94.8 0.0 7e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.7 ABX12960.1 - 1.3e-18 67.0 0.1 2e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.1 ABX12960.1 - 8.3e-11 42.3 1.9 2.3e-09 37.6 0.2 2.1 1 1 1 2 2 2 1 AAA domain SMC_N PF02463.14 ABX12960.1 - 1.8e-05 24.0 0.3 2.7e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 ABX12960.1 - 0.002 18.4 0.1 0.0058 16.9 0.1 1.8 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 ABX12960.1 - 0.01 15.3 0.3 0.91 8.8 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain AAA_25 PF13481.1 ABX12960.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 ABX12960.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 ABX12960.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.1 ABX12960.1 - 0.13 11.2 1.0 0.61 9.0 0.3 2.0 1 1 1 2 2 2 0 AAA ATPase domain KH_5 PF13184.1 ABX12961.1 - 7.3e-09 35.3 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 NusA-like KH domain Cys_rich_KTR PF14205.1 ABX12961.1 - 0.012 15.0 0.3 4 6.9 0.0 2.5 2 0 0 2 2 2 0 Cysteine-rich KTR Ribosomal_S2 PF00318.15 ABX12961.1 - 0.11 11.7 0.1 0.11 11.7 0.1 1.4 2 0 0 2 2 2 0 Ribosomal protein S2 tRNA-synt_2 PF00152.15 ABX12962.1 - 7.3e-89 297.8 0.0 1.2e-88 297.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 ABX12962.1 - 8e-12 44.8 1.3 1.4e-11 44.0 0.9 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 ABX12962.1 - 0.00094 18.4 0.3 0.12 11.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Acyl_transf_3 PF01757.17 ABX12964.1 - 0.0058 15.5 0.7 0.0064 15.3 0.5 1.0 1 0 0 1 1 1 1 Acyltransferase family COX1 PF00115.15 ABX12964.1 - 0.012 14.2 0.3 0.013 14.1 0.2 1.0 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I E1-E2_ATPase PF00122.15 ABX12964.1 - 0.31 10.0 1.3 0.37 9.7 0.9 1.0 1 0 0 1 1 1 0 E1-E2 ATPase PrgI PF12666.2 ABX12964.1 - 3.4 7.8 6.1 5.6 7.1 4.2 1.3 1 1 0 1 1 1 0 PrgI family protein Iso_dh PF00180.15 ABX12965.1 - 2.6e-100 335.7 0.3 2.9e-100 335.6 0.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 ABX12965.1 - 0.00061 19.0 0.0 0.0013 18.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA DUF4030 PF13222.1 ABX12965.1 - 0.071 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) HMGL-like PF00682.14 ABX12966.1 - 1.2e-75 254.2 1.5 2.2e-75 253.3 1.1 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 ABX12966.1 - 5.9e-29 100.5 0.5 1.1e-28 99.6 0.3 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Glyco_hydro_97 PF10566.4 ABX12966.1 - 0.00058 19.0 0.1 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Glycoside hydrolase 97 AP_endonuc_2 PF01261.19 ABX12966.1 - 0.049 12.9 0.4 1.2 8.3 0.1 2.7 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel ALS_ss_C PF10369.4 ABX12967.1 - 5e-25 87.0 0.8 1.8e-22 78.8 0.0 2.6 2 1 0 2 2 2 2 Small subunit of acetolactate synthase ACT_5 PF13710.1 ABX12967.1 - 9.2e-16 57.4 0.0 1.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT PF01842.20 ABX12967.1 - 1.9e-13 49.5 0.0 3.3e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 ABX12967.1 - 7.5e-05 22.9 0.1 0.00017 21.8 0.1 1.6 1 0 0 1 1 1 1 ACT domain Acylphosphatase PF00708.13 ABX12967.1 - 0.012 15.7 0.1 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Acylphosphatase DUF2067 PF09840.4 ABX12967.1 - 0.034 13.6 0.1 0.038 13.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) DapH_N PF08503.5 ABX12967.1 - 0.054 13.6 0.2 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal Transaldolase PF00923.14 ABX12967.1 - 0.087 11.9 0.6 0.25 10.4 0.4 1.6 1 1 0 1 1 1 0 Transaldolase TPP_enzyme_N PF02776.13 ABX12968.1 - 1.5e-61 206.8 0.7 5.2e-59 198.5 0.2 2.5 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 ABX12968.1 - 4.6e-47 159.4 1.2 2.1e-46 157.2 0.1 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 ABX12968.1 - 2.9e-45 153.3 0.1 7.7e-45 152.0 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain fn3 PF00041.16 ABX12969.1 - 0 2911.0 427.3 2.4e-16 59.6 1.1 81.4 82 1 0 82 82 82 78 Fibronectin type III domain SusE PF14292.1 ABX12969.1 - 1e-40 138.3 252.9 0.025 14.3 0.5 61.8 58 7 9 70 70 70 23 SusE outer membrane protein FlgD_ig PF13860.1 ABX12969.1 - 2.2e-13 49.7 128.5 0.025 14.3 0.2 23.9 26 0 0 26 26 26 12 FlgD Ig-like domain Interfer-bind PF09294.5 ABX12969.1 - 5.5e-10 39.2 0.0 16 5.5 0.0 16.7 23 0 0 23 23 23 1 Interferon-alpha/beta receptor, fibronectin type III Phage_head_chap PF11113.3 ABX12969.1 - 0.014 15.2 1.1 47 3.9 0.0 7.2 7 0 0 7 7 7 0 Head assembly gene product ArsR PF09824.4 ABX12969.1 - 0.1 11.9 0.1 1.1e+02 2.0 0.0 5.6 7 0 0 7 7 7 0 ArsR transcriptional regulator Aminotran_4 PF01063.14 ABX12969.1 - 0.91 8.9 0.0 34 3.7 0.0 2.4 2 0 0 2 2 2 0 Aminotransferase class IV ATP-synt_D PF01813.12 ABX12969.1 - 2.8 7.4 0.0 4.9 6.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase subunit D DUF2452 PF10504.4 ABX12969.1 - 4.6 6.4 0.2 79 2.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2452) IncA PF04156.9 ABX12970.1 - 6.4e-05 22.6 8.9 0.00011 21.8 6.2 1.4 1 0 0 1 1 1 1 IncA protein Spc7 PF08317.6 ABX12970.1 - 0.0011 17.7 7.3 0.0014 17.3 5.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein FTA4 PF13093.1 ABX12970.1 - 0.0027 17.1 2.4 0.0055 16.1 1.7 1.4 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TMCO5 PF14992.1 ABX12970.1 - 0.03 13.4 10.7 0.047 12.8 7.4 1.2 1 0 0 1 1 1 0 TMCO5 family Tropomyosin_1 PF12718.2 ABX12970.1 - 0.031 14.1 18.9 0.51 10.1 3.7 2.2 1 1 1 2 2 2 0 Tropomyosin like Rab5-bind PF09311.6 ABX12970.1 - 0.064 13.1 17.2 0.18 11.6 12.1 1.6 1 1 0 1 1 1 0 Rabaptin-like protein CENP-Q PF13094.1 ABX12970.1 - 0.067 13.2 11.2 0.14 12.2 7.8 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Mt_ATP-synt_D PF05873.7 ABX12970.1 - 0.085 12.4 1.4 0.16 11.6 0.9 1.4 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Transglut_core PF01841.14 ABX12970.1 - 0.11 12.7 0.0 0.62 10.2 0.0 2.1 2 1 0 2 2 2 0 Transglutaminase-like superfamily F_actin_bind PF08919.5 ABX12970.1 - 0.12 12.1 2.2 0.3 10.7 1.5 1.7 1 1 0 1 1 1 0 F-actin binding ERM PF00769.14 ABX12970.1 - 0.16 11.4 12.8 0.25 10.8 8.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Mnd1 PF03962.10 ABX12970.1 - 0.16 11.5 11.0 0.3 10.7 7.6 1.4 1 0 0 1 1 1 0 Mnd1 family Bacillus_HBL PF05791.6 ABX12970.1 - 0.18 11.1 5.3 0.32 10.3 3.7 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.5 ABX12970.1 - 0.22 11.6 5.2 0.38 10.8 3.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 ABX12970.1 - 0.45 9.4 11.6 0.65 8.8 8.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 ABX12970.1 - 0.45 9.5 17.5 0.69 8.9 12.1 1.2 1 0 0 1 1 1 0 Tropomyosin ACCA PF03255.9 ABX12970.1 - 0.69 9.4 7.5 2.9 7.4 0.4 3.0 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FUSC PF04632.7 ABX12970.1 - 0.77 8.1 1.7 1 7.6 1.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DnaI_N PF07319.6 ABX12970.1 - 0.81 9.9 4.7 2.3 8.5 3.3 1.8 1 1 0 1 1 1 0 Primosomal protein DnaI N-terminus Prefoldin PF02996.12 ABX12970.1 - 0.89 9.2 11.0 2.2 7.9 0.5 3.2 3 0 0 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.4 ABX12970.1 - 0.9 9.7 13.9 3.1 7.9 3.0 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 ABX12970.1 - 1.1 7.6 11.8 1.6 7.0 8.2 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 ABX12970.1 - 1.6 8.5 10.1 3 7.5 6.7 1.6 1 1 0 1 1 1 0 Laminin Domain II FlxA PF14282.1 ABX12970.1 - 1.7 8.5 20.6 12 5.9 14.2 2.4 1 1 0 1 1 1 0 FlxA-like protein Seryl_tRNA_N PF02403.17 ABX12970.1 - 2.2 8.3 15.5 1.4 8.9 2.7 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.13 ABX12970.1 - 2.4 7.9 5.3 19 5.0 0.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF904 PF06005.7 ABX12970.1 - 2.7 8.3 17.2 18 5.6 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 ABX12970.1 - 3.1 8.1 10.7 7.4 6.9 2.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) eIF3_N PF09440.5 ABX12970.1 - 3.6 7.7 7.3 6 7.0 4.6 1.7 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain DUF4559 PF15112.1 ABX12970.1 - 3.6 6.6 7.1 5.5 6.0 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Fzo_mitofusin PF04799.8 ABX12970.1 - 3.6 6.9 9.8 3.2 7.1 4.7 2.1 1 1 1 2 2 2 0 fzo-like conserved region BBP1_C PF15272.1 ABX12970.1 - 3.8 7.0 10.5 11 5.4 7.2 1.7 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal V_ATPase_I PF01496.14 ABX12970.1 - 3.8 5.2 10.7 7.9 4.1 7.5 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family PspA_IM30 PF04012.7 ABX12970.1 - 4 6.7 19.2 2.9e+02 0.6 13.0 2.7 1 1 0 1 1 1 0 PspA/IM30 family ADIP PF11559.3 ABX12970.1 - 4.3 7.2 13.6 4.4 7.1 1.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 ABX12970.1 - 4.6 7.2 16.5 66 3.5 11.6 2.4 1 1 0 1 1 1 0 DivIVA protein DUF3450 PF11932.3 ABX12970.1 - 5.5 6.1 16.4 0.38 9.9 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TBPIP PF07106.8 ABX12970.1 - 7.3 6.0 13.3 3.9 7.0 6.1 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 ABX12970.1 - 8.3 6.9 20.5 0.96 9.9 3.4 3.6 2 1 2 4 4 3 0 N-terminal domain of unknown function (DUF4140) HAMP PF00672.20 ABX12972.1 - 1.1e-13 51.0 0.0 6.5e-13 48.6 0.0 2.3 2 0 0 2 2 2 1 HAMP domain DUF536 PF04394.9 ABX12972.1 - 2.5 7.8 7.2 0.14 11.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF536 SnoaL_3 PF13474.1 ABX12973.1 - 9.7e-10 38.5 0.0 1.1e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 ABX12973.1 - 2.6e-05 24.3 0.0 3.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.5 ABX12973.1 - 8.5e-05 22.4 0.1 0.00018 21.4 0.1 1.5 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association DeoC PF01791.4 ABX12974.1 - 9.9e-22 77.3 0.0 1.3e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Rossmann-like PF10727.4 ABX12974.1 - 0.081 12.6 0.1 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Rossmann-like domain DUF2201_N PF13203.1 ABX12974.1 - 0.52 9.4 10.6 0.73 8.9 7.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Gti1_Pac2 PF09729.4 ABX12974.1 - 1.2 9.0 7.6 2.3 8.0 5.2 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4175 PF13779.1 ABX12974.1 - 1.6 6.3 12.2 2.1 5.9 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Rtf2 PF04641.7 ABX12974.1 - 9.7 5.2 19.7 15 4.7 13.6 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger ADH_N PF08240.7 ABX12975.1 - 1.7e-24 85.6 2.8 3.2e-24 84.7 1.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ABX12975.1 - 2.2e-23 82.2 0.1 3e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ABX12975.1 - 0.00018 22.3 0.1 0.00031 21.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CagE_TrbE_VirB PF03135.9 ABX12975.1 - 0.035 13.8 0.2 0.065 13.0 0.2 1.4 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Methyltransf_18 PF12847.2 ABX12975.1 - 0.054 14.0 0.1 0.19 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain GARS_N PF02844.10 ABX12975.1 - 0.057 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain ATP-synt_F PF01990.12 ABX12976.1 - 9e-15 54.8 0.0 1e-14 54.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Trp_syntA PF00290.15 ABX12976.1 - 0.00075 18.1 0.0 0.00075 18.1 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain ADH_zinc_N PF00107.21 ABX12976.1 - 0.1 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SWIM PF04434.12 ABX12979.1 - 0.00063 19.1 0.2 0.00095 18.5 0.1 1.3 1 0 0 1 1 1 1 SWIM zinc finger Metallophos PF00149.23 ABX12980.1 - 4.9e-10 39.1 0.3 1.1e-08 34.7 0.0 2.1 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ABX12980.1 - 1.4e-06 28.2 0.1 3e-06 27.1 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DNA_pol_E_B PF04042.11 ABX12980.1 - 0.004 16.4 0.1 0.011 14.9 0.1 1.7 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Epimerase_2 PF02350.14 ABX12980.1 - 0.069 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Metallophos_3 PF14582.1 ABX12980.1 - 0.09 11.9 0.1 1.3 8.0 0.0 2.1 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily CPSase_L_D2 PF02786.12 ABX12981.1 - 5.9e-101 336.1 0.1 1.5e-73 246.5 0.1 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 ABX12981.1 - 7.2e-40 136.6 0.0 7.6e-19 68.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_D3 PF02787.14 ABX12981.1 - 6.5e-39 132.4 0.1 1.7e-38 131.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 ABX12981.1 - 4.7e-35 120.0 0.1 6.5e-18 64.8 0.0 3.1 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 ABX12981.1 - 1.5e-23 83.0 0.0 6.5e-09 34.9 0.0 4.4 4 1 0 4 4 4 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 ABX12981.1 - 4.6e-20 71.6 0.3 1.1e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ABX12981.1 - 6.5e-15 55.0 1.2 1.6e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 ABX12981.1 - 7.3e-15 54.6 0.1 3.3e-14 52.5 0.1 2.3 1 0 0 1 1 1 1 MGS-like domain GARS_A PF01071.14 ABX12981.1 - 1.4e-10 41.1 1.4 8.5e-05 22.1 0.1 2.8 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 ABX12981.1 - 1.4e-06 28.2 1.4 0.012 15.4 0.0 2.7 3 0 0 3 3 2 2 ATP-grasp domain ATP-grasp_2 PF08442.5 ABX12981.1 - 0.002 17.5 0.3 0.01 15.2 0.1 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.1 ABX12981.1 - 0.018 14.2 0.1 0.16 11.2 0.1 2.4 2 1 1 3 3 3 0 ATP-grasp domain Pyr_redox PF00070.22 ABX12981.1 - 2.1 8.7 6.5 0.88 10.0 0.2 3.6 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase CPSase_sm_chain PF00988.17 ABX12982.1 - 7e-50 167.9 0.0 2.4e-49 166.1 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 ABX12982.1 - 5.8e-45 153.1 0.0 1.1e-44 152.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ABX12982.1 - 5.6e-08 32.4 0.2 4.6e-06 26.2 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 RinB PF06116.7 ABX12983.1 - 0.25 10.9 3.0 0.19 11.3 0.1 2.4 2 0 0 2 2 2 0 Transcriptional activator RinB AAA PF00004.24 ABX12984.1 - 1.1e-37 129.1 0.0 3e-37 127.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 ABX12984.1 - 5.1e-11 42.3 2.1 1.1e-10 41.2 0.7 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_2 PF07724.9 ABX12984.1 - 1.9e-07 31.1 0.1 4.9e-07 29.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 ABX12984.1 - 4.6e-06 26.8 0.0 2.5e-05 24.4 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 ABX12984.1 - 1.9e-05 24.7 0.2 0.032 14.2 0.0 3.7 2 1 1 4 4 4 1 AAA ATPase domain Vps4_C PF09336.5 ABX12984.1 - 2.2e-05 24.2 0.1 0.0001 22.0 0.0 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Zeta_toxin PF06414.7 ABX12984.1 - 3.7e-05 22.9 0.0 0.0001 21.5 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.7 ABX12984.1 - 4.7e-05 22.5 0.0 0.00014 21.0 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 ABX12984.1 - 6.4e-05 22.6 0.0 0.00018 21.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ABX12984.1 - 0.00016 21.5 0.0 0.0043 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ABX12984.1 - 0.0002 20.8 0.2 0.0012 18.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ABX12984.1 - 0.00085 18.9 0.0 0.012 15.2 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ABX12984.1 - 0.0011 18.8 0.0 0.0032 17.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 ABX12984.1 - 0.0032 17.1 0.3 0.016 14.9 0.1 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ABX12984.1 - 0.0034 18.2 0.0 0.0084 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ABX12984.1 - 0.0036 17.0 0.0 3.5 7.2 0.0 2.5 1 1 1 2 2 2 2 Archaeal ATPase Mg_chelatase PF01078.16 ABX12984.1 - 0.004 16.3 0.1 0.0091 15.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 ABX12984.1 - 0.005 16.2 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 ABX12984.1 - 0.0053 16.4 0.1 0.016 14.9 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain TIP49 PF06068.8 ABX12984.1 - 0.0091 14.7 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus KAP_NTPase PF07693.9 ABX12984.1 - 0.015 14.2 0.0 0.44 9.4 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 ABX12984.1 - 0.021 14.9 0.2 0.37 10.9 0.0 2.6 2 1 0 2 2 2 0 RNA helicase TPR_11 PF13414.1 ABX12984.1 - 0.024 14.2 0.9 0.055 13.1 0.6 1.6 1 0 0 1 1 1 0 TPR repeat TPR_6 PF13174.1 ABX12984.1 - 0.047 14.1 0.1 0.67 10.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_18 PF13238.1 ABX12984.1 - 0.056 13.7 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 ABX12984.1 - 0.071 12.2 0.1 1.6 7.7 0.0 2.2 1 1 1 2 2 2 0 KaiC ResIII PF04851.10 ABX12984.1 - 0.088 12.6 0.0 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 ABX12984.1 - 0.093 12.3 0.0 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 ABX12984.1 - 0.098 12.9 0.2 2.6 8.3 0.0 2.8 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.12 ABX12984.1 - 0.11 11.3 0.0 0.24 10.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 ABX12984.1 - 0.11 11.7 0.2 0.23 10.6 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein HHH_8 PF14716.1 ABX12985.1 - 0.003 17.6 1.0 0.029 14.5 0.1 2.5 1 1 1 2 2 2 1 Helix-hairpin-helix domain DUF948 PF06103.6 ABX12985.1 - 0.0085 15.9 0.8 0.044 13.6 0.0 2.1 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Nup88 PF10168.4 ABX12985.1 - 0.06 11.1 1.4 0.071 10.9 0.9 1.1 1 0 0 1 1 1 0 Nuclear pore component Swi5 PF07061.6 ABX12985.1 - 0.091 12.5 3.2 0.082 12.7 1.1 1.7 2 0 0 2 2 2 0 Swi5 RE_Alw26IDE PF09665.5 ABX12985.1 - 0.18 10.5 3.5 0.21 10.2 2.5 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Syntaxin PF00804.20 ABX12985.1 - 0.61 10.2 13.7 0.87 9.7 4.0 2.4 1 1 1 2 2 2 0 Syntaxin Syntaxin_2 PF14523.1 ABX12985.1 - 4.4 7.4 9.1 15 5.7 1.7 2.8 1 1 2 3 3 3 0 Syntaxin-like protein DNA_topoisoIV PF00521.15 ABX12986.1 - 0.012 14.4 0.6 0.017 13.9 0.4 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A TrmB PF01978.14 ABX12987.1 - 1.8e-18 65.9 0.2 7.1e-17 60.8 0.1 2.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 ABX12987.1 - 8.8e-05 21.5 0.1 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_11 PF08279.7 ABX12987.1 - 0.02 14.5 0.4 0.13 11.9 0.0 2.4 2 0 0 2 2 2 0 HTH domain PadR PF03551.9 ABX12987.1 - 0.14 11.9 0.4 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 Transcriptional regulator PadR-like family YjgF_endoribonc PF14588.1 ABX12988.1 - 5.7e-34 117.1 0.0 6.3e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 ABX12988.1 - 1.6e-19 69.8 0.0 2.1e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP SDF PF00375.13 ABX12989.1 - 2.2e-114 382.2 46.2 2.5e-114 382.0 32.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Pyridox_oxidase PF01243.15 ABX12990.1 - 4.9e-07 29.6 0.0 6.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_L21e PF01157.13 ABX12990.1 - 0.017 14.8 0.6 0.017 14.8 0.4 1.7 1 1 1 2 2 2 0 Ribosomal protein L21e Pyridox_ox_2 PF12900.2 ABX12990.1 - 0.024 14.4 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF640 PF04852.7 ABX12990.1 - 0.061 13.5 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF640) VanZ PF04892.7 ABX12991.1 - 0.0013 18.6 0.5 0.003 17.5 0.3 1.7 1 1 0 1 1 1 1 VanZ like family DUF1469 PF07332.6 ABX12991.1 - 0.013 15.1 1.4 0.013 15.1 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) DoxX_2 PF13564.1 ABX12991.1 - 0.11 12.5 0.4 0.11 12.5 0.3 2.3 2 0 0 2 2 2 0 DoxX-like family DUF202 PF02656.10 ABX12991.1 - 0.15 12.2 1.9 16 5.8 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PrgI PF12666.2 ABX12991.1 - 0.87 9.7 5.6 0.81 9.8 0.1 2.6 1 1 2 3 3 3 0 PrgI family protein RseC_MucC PF04246.7 ABX12991.1 - 1.2 8.7 5.4 0.26 10.8 0.4 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC COX14 PF14880.1 ABX12991.1 - 1.9 8.1 4.6 0.41 10.3 0.3 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF3179 PF11376.3 ABX12992.1 - 1.9e-97 325.5 0.0 2.2e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3179) DoxX PF07681.7 ABX12993.1 - 2.2e-11 44.0 1.5 2.2e-11 44.0 1.0 1.5 2 0 0 2 2 2 1 DoxX DoxD PF04173.8 ABX12993.1 - 1.1e-05 25.1 1.2 1.4e-05 24.8 0.8 1.2 1 0 0 1 1 1 1 TQO small subunit DoxD DoxX_2 PF13564.1 ABX12993.1 - 0.0002 21.2 3.9 0.00038 20.3 2.7 1.6 1 1 0 1 1 1 1 DoxX-like family DHHA1 PF02272.14 ABX12994.1 - 3.4e-12 45.8 1.3 8.1e-12 44.6 0.2 2.2 2 0 0 2 2 2 1 DHHA1 domain DHH PF01368.15 ABX12994.1 - 0.00032 20.3 2.7 0.0012 18.5 1.9 2.0 1 1 0 1 1 1 1 DHH family Utp14 PF04615.8 ABX12994.1 - 0.0063 14.7 7.6 0.0086 14.3 5.3 1.1 1 0 0 1 1 1 1 Utp14 protein Citrate_synt PF00285.16 ABX12995.1 - 9e-142 472.0 0.1 1e-141 471.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase DUF1940 PF09155.5 ABX12995.1 - 0.0066 16.2 0.1 0.031 14.1 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1940) UPF0146 PF03686.8 ABX12995.1 - 0.12 12.2 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Copper-bind PF00127.15 ABX12998.1 - 6e-10 39.2 1.3 1.1e-09 38.4 0.1 2.0 2 1 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 ABX12998.1 - 1.4e-06 28.1 0.0 1.1e-05 25.1 0.0 2.4 3 0 0 3 3 3 1 Cupredoxin-like domain UvrC_HhH_N PF08459.6 ABX12999.1 - 2.3e-51 173.4 1.6 3.8e-51 172.7 0.0 2.2 3 1 0 3 3 3 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.19 ABX12999.1 - 4.7e-13 49.2 1.1 4.7e-13 49.2 0.7 2.2 2 0 0 2 2 2 1 GIY-YIG catalytic domain UVR PF02151.14 ABX12999.1 - 3.4e-09 35.9 0.7 8.1e-09 34.7 0.5 1.7 1 0 0 1 1 1 1 UvrB/uvrC motif ABC_tran PF00005.22 ABX13000.1 - 5.2e-23 81.8 0.4 2.3e-09 37.6 0.1 4.5 3 1 0 3 3 3 3 ABC transporter SMC_N PF02463.14 ABX13000.1 - 1.8e-10 40.4 1.0 0.055 12.7 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ABX13000.1 - 2.2e-08 33.5 0.1 0.0093 15.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 ABX13000.1 - 3.1e-07 30.6 17.4 0.0019 18.1 0.7 5.1 4 1 1 5 5 5 2 AAA domain AAA_16 PF13191.1 ABX13000.1 - 3.1e-07 30.5 0.0 0.016 15.2 0.0 4.0 5 0 0 5 5 4 2 AAA ATPase domain AAA_14 PF13173.1 ABX13000.1 - 8.8e-07 28.8 0.2 0.18 11.7 0.0 3.8 3 1 1 4 4 4 2 AAA domain AAA_25 PF13481.1 ABX13000.1 - 1.7e-06 27.5 0.9 0.16 11.3 0.0 4.3 5 1 0 5 5 5 2 AAA domain DUF258 PF03193.11 ABX13000.1 - 2.9e-06 26.5 0.2 0.023 13.8 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 ABX13000.1 - 5.7e-06 26.8 7.7 0.00023 21.5 0.2 3.4 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.1 ABX13000.1 - 6.4e-06 26.0 0.2 0.12 12.1 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_18 PF13238.1 ABX13000.1 - 1.9e-05 24.9 0.0 0.3 11.4 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 ABX13000.1 - 2.5e-05 24.4 2.4 0.18 11.9 0.0 4.1 5 1 0 5 5 4 2 AAA domain AAA_10 PF12846.2 ABX13000.1 - 3.7e-05 23.3 1.0 0.12 11.7 0.0 3.2 4 0 0 4 4 3 2 AAA-like domain NB-ARC PF00931.17 ABX13000.1 - 8.4e-05 21.5 0.0 0.42 9.4 0.0 3.6 4 0 0 4 4 4 1 NB-ARC domain Arch_ATPase PF01637.13 ABX13000.1 - 9.5e-05 22.2 1.1 0.16 11.6 0.0 3.7 3 0 0 3 3 3 1 Archaeal ATPase AAA_17 PF13207.1 ABX13000.1 - 0.00017 22.4 7.8 0.2 12.5 0.3 4.1 5 1 0 5 5 2 2 AAA domain MMR_HSR1 PF01926.18 ABX13000.1 - 0.00025 20.9 4.4 0.0073 16.2 0.1 3.6 3 1 0 3 3 3 1 50S ribosome-binding GTPase NACHT PF05729.7 ABX13000.1 - 0.00039 20.1 0.0 0.28 10.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 ABX13000.1 - 0.00051 19.7 0.0 1.1 9.1 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain APS_kinase PF01583.15 ABX13000.1 - 0.00054 19.6 0.1 1.2 8.7 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase MobB PF03205.9 ABX13000.1 - 0.00055 19.6 0.3 0.066 12.9 0.1 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 ABX13000.1 - 0.0007 19.1 0.1 0.096 12.1 0.1 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 ABX13000.1 - 0.00094 18.7 0.1 0.95 8.9 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family KaiC PF06745.8 ABX13000.1 - 0.0011 18.1 0.2 1.1 8.2 0.0 3.1 3 0 0 3 3 3 1 KaiC cobW PF02492.14 ABX13000.1 - 0.002 17.6 0.3 0.27 10.6 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DnaJ_CXXCXGXG PF00684.14 ABX13000.1 - 0.0023 17.9 0.4 0.0023 17.9 0.3 4.1 4 1 1 5 5 4 1 DnaJ central domain NTPase_1 PF03266.10 ABX13000.1 - 0.0036 17.0 0.2 0.6 9.8 0.0 3.5 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.17 ABX13000.1 - 0.005 16.9 0.0 1.5 9.0 0.0 3.0 2 0 0 2 2 2 1 RNA helicase T2SE PF00437.15 ABX13000.1 - 0.0056 15.6 0.1 1.9 7.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein ArgK PF03308.11 ABX13000.1 - 0.0064 15.2 0.0 0.26 10.0 0.0 2.7 2 0 0 2 2 2 1 ArgK protein PRK PF00485.13 ABX13000.1 - 0.01 15.3 0.3 0.27 10.7 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.4 ABX13000.1 - 0.016 14.1 0.0 5.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 ABX13000.1 - 0.025 14.5 0.6 5.7 6.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 ABX13000.1 - 0.029 14.8 0.2 8.1 6.9 0.1 3.1 3 0 0 3 3 2 0 Miro-like protein Zeta_toxin PF06414.7 ABX13000.1 - 0.05 12.6 0.0 2.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin zinc_ribbon_2 PF13240.1 ABX13000.1 - 0.053 13.0 3.3 1.9 8.0 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain AAA_30 PF13604.1 ABX13000.1 - 0.077 12.5 0.1 18 4.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain DAP3 PF10236.4 ABX13000.1 - 0.12 11.2 0.0 6.1 5.6 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 UvrB PF12344.3 ABX13001.1 - 1.5e-21 75.6 5.5 4.1e-21 74.2 3.8 1.8 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.26 ABX13001.1 - 2.2e-15 56.2 0.0 7.7e-15 54.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UVR PF02151.14 ABX13001.1 - 2.1e-09 36.6 4.1 2.1e-09 36.6 2.8 3.2 3 0 0 3 3 3 1 UvrB/uvrC motif ResIII PF04851.10 ABX13001.1 - 4.7e-08 33.0 0.1 4.7e-08 33.0 0.0 3.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ABX13001.1 - 9.4e-08 31.7 0.4 7.6e-05 22.2 0.0 3.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase UB2H PF14814.1 ABX13001.1 - 0.0016 18.1 0.0 0.0079 15.8 0.0 2.3 1 1 0 1 1 1 1 Bifunctional transglycosylase second domain AAA_19 PF13245.1 ABX13001.1 - 0.0025 17.5 0.1 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 ABX13001.1 - 0.017 14.7 0.4 0.38 10.3 0.0 2.8 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.1 ABX13001.1 - 0.043 13.9 2.8 3 8.0 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.1 ABX13001.1 - 0.11 12.3 0.4 0.61 9.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF885 PF05960.6 ABX13001.1 - 0.11 11.5 2.9 1.3 8.0 2.0 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Met_synt_B12 PF02965.12 ABX13001.1 - 0.12 11.5 2.2 0.13 11.3 0.1 2.0 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain Tup_N PF08581.5 ABX13001.1 - 1 9.5 13.0 0.34 11.1 0.1 3.5 3 1 0 3 3 3 0 Tup N-terminal Pyridox_ox_2 PF12900.2 ABX13002.1 - 4.8e-20 71.8 0.0 6.1e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 ABX13002.1 - 3.6e-14 52.5 0.0 6.4e-14 51.7 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.7 ABX13002.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain Imm11 PF15563.1 ABX13003.1 - 0.028 13.5 1.0 0.042 12.9 0.5 1.4 1 1 0 1 1 1 0 Immunity protein 11 RNA_pol_Rpc34 PF05158.7 ABX13003.1 - 0.052 12.7 0.1 0.052 12.7 0.0 1.4 2 0 0 2 2 2 0 RNA polymerase Rpc34 subunit PqqD PF05402.7 ABX13003.1 - 0.13 12.3 0.1 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) CRF PF00473.12 ABX13003.1 - 0.32 11.1 4.2 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Corticotropin-releasing factor family Adeno_E4 PF05385.6 ABX13003.1 - 4.6 7.2 6.4 0.41 10.6 0.1 2.0 2 0 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein Bac_luciferase PF00296.15 ABX13005.1 - 1.3e-55 188.7 0.0 1.6e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Fe-ADH PF00465.14 ABX13006.1 - 1.9e-50 171.5 0.0 3.9e-50 170.5 0.0 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 ABX13006.1 - 1.1e-17 64.1 0.0 1.5e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 ABX13006.1 - 2.7e-05 23.2 0.0 0.0022 16.9 0.0 2.1 2 0 0 2 2 2 2 3-dehydroquinate synthase DUF4147 PF13660.1 ABX13007.1 - 6.9e-74 247.9 0.0 1.1e-73 247.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.8 ABX13007.1 - 4e-27 94.4 1.5 7.6e-27 93.5 0.6 1.9 2 0 0 2 2 2 1 MOFRL family Peptidase_C13 PF01650.13 ABX13007.1 - 0.00015 21.1 2.0 0.016 14.4 0.0 3.0 1 1 1 3 3 3 2 Peptidase C13 family Lactamase_B_2 PF12706.2 ABX13009.1 - 0.00071 19.1 0.3 0.37 10.3 0.4 2.9 2 1 0 2 2 2 2 Beta-lactamase superfamily domain RMMBL PF07521.7 ABX13009.1 - 0.00089 19.0 0.0 0.00089 19.0 0.0 2.1 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase DRMBL PF07522.9 ABX13009.1 - 0.034 14.1 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase Formyl_trans_N PF00551.14 ABX13010.1 - 5.2e-45 153.2 0.0 5.9e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Cupin_2 PF07883.6 ABX13011.1 - 3.9e-11 42.2 0.0 8.7e-11 41.1 0.0 1.5 2 0 0 2 2 2 1 Cupin domain CENP-C_C PF11699.3 ABX13011.1 - 2.3e-06 27.5 0.1 2.8e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.14 ABX13011.1 - 3e-05 23.7 0.0 3.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.9 ABX13011.1 - 0.014 15.3 0.5 0.019 14.9 0.3 1.5 1 1 0 1 1 1 0 ARD/ARD' family Pirin_C PF05726.8 ABX13011.1 - 0.016 15.2 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Pirin C-terminal cupin domain ABM PF03992.11 ABX13012.1 - 1.5e-09 37.7 0.0 1.8e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase THF_DHG_CYH_C PF02882.14 ABX13013.1 - 3.7e-60 201.6 0.6 5.5e-60 201.0 0.4 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 ABX13013.1 - 4.1e-43 146.1 0.9 7.8e-43 145.2 0.6 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Shikimate_DH PF01488.15 ABX13013.1 - 0.0036 17.4 0.1 0.0081 16.2 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1884 PF08967.5 ABX13013.1 - 0.037 14.0 0.0 0.13 12.3 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1884) Hydrolase PF00702.21 ABX13013.1 - 0.044 14.1 0.1 0.12 12.7 0.0 1.8 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Saccharop_dh PF03435.13 ABX13013.1 - 0.061 12.2 0.9 0.18 10.7 0.1 2.0 2 1 1 3 3 3 0 Saccharopine dehydrogenase 5-FTHF_cyc-lig PF01812.15 ABX13014.1 - 2e-40 138.5 0.0 2.2e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Ribosomal_S6e PF01092.14 ABX13014.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S6e GARS_A PF01071.14 ABX13015.1 - 7.1e-81 270.4 0.2 9.4e-81 270.0 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 ABX13015.1 - 4.3e-34 116.9 0.1 1.2e-33 115.4 0.0 1.9 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 ABX13015.1 - 6.6e-32 109.5 0.0 2.1e-31 107.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 ABX13015.1 - 3.7e-12 46.3 0.0 6.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 ABX13015.1 - 7.1e-08 31.9 0.0 1.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 ABX13015.1 - 1.2e-06 28.4 0.0 1.8e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 ABX13015.1 - 4.1e-06 26.2 0.0 7.6e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.5 ABX13015.1 - 4.5e-06 26.1 0.0 8.5e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ABX13015.1 - 1.3e-05 24.7 0.1 2.1e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 ABX13015.1 - 1.9e-05 23.5 0.0 0.00036 19.4 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.6 ABX13015.1 - 0.00012 21.6 0.0 0.00031 20.2 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.1 ABX13015.1 - 0.007 15.4 0.1 0.034 13.2 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp tRNA-synt_1 PF00133.17 ABX13016.1 - 6.8e-147 490.0 0.7 1e-146 489.4 0.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 ABX13016.1 - 3.7e-31 107.9 0.2 9e-31 106.6 0.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 ABX13016.1 - 3.8e-23 81.8 0.6 1.4e-08 33.8 0.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 ABX13016.1 - 6.8e-05 22.1 0.0 0.0015 17.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 ABX13016.1 - 9.3e-05 21.2 0.0 0.00024 19.8 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (K) Zn-ribbon_8 PF09723.5 ABX13016.1 - 0.095 12.6 2.0 0.62 10.0 0.0 3.0 3 0 0 3 3 3 0 Zinc ribbon domain Ferritin PF00210.19 ABX13017.1 - 7.3e-20 71.1 0.0 1e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 ABX13017.1 - 0.007 16.6 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Rubrerythrin TF_Zn_Ribbon PF08271.7 ABX13018.1 - 0.0038 16.5 0.0 0.0056 15.9 0.0 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding ATP-grasp_2 PF08442.5 ABX13019.1 - 4.7e-45 153.4 2.7 8.2e-45 152.6 1.9 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 ABX13019.1 - 1.1e-14 54.2 0.3 2.5e-14 53.1 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 ABX13019.1 - 2.4e-13 49.8 0.2 9.2e-13 47.9 0.1 1.9 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 ABX13019.1 - 4.4e-06 26.1 0.0 7.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 ABX13019.1 - 3.6e-05 23.5 0.0 6.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain DUF362 PF04015.7 ABX13019.1 - 0.019 14.4 0.0 0.39 10.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF362) ATP-grasp PF02222.17 ABX13019.1 - 0.038 13.3 0.1 0.075 12.3 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp domain CoA_binding PF02629.14 ABX13020.1 - 1.4e-21 76.7 2.4 2.4e-21 76.0 0.4 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 ABX13020.1 - 7.2e-08 32.1 0.1 1.3e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding_2 PF13380.1 ABX13020.1 - 3.9e-06 27.0 0.0 6.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 ABX13020.1 - 1.3e-05 25.6 0.1 2.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Succ_CoA_lig PF13607.1 ABX13020.1 - 0.0002 20.9 0.0 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain zinc_ribbon_2 PF13240.1 ABX13021.1 - 7.2e-05 22.1 2.1 9.9e-05 21.7 1.4 1.2 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 ABX13021.1 - 0.0016 17.6 1.4 0.0021 17.2 1.0 1.2 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 ABX13021.1 - 0.0021 17.8 0.6 0.0023 17.6 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon Ribosomal_L40e PF01020.12 ABX13021.1 - 0.031 13.8 6.0 0.18 11.4 2.6 2.1 1 1 1 2 2 2 0 Ribosomal L40e family zf-RING_4 PF14570.1 ABX13021.1 - 0.18 11.3 1.7 0.25 10.9 1.2 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CTV_P23 PF04808.7 ABX13021.1 - 0.21 10.9 0.7 0.21 10.9 0.5 1.1 1 0 0 1 1 1 0 Citrus tristeza virus (CTV) P23 protein zf-CCHC PF00098.18 ABX13021.1 - 0.58 10.1 6.7 0.59 10.1 0.5 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-tcix PF14952.1 ABX13021.1 - 1.1 8.6 10.2 1.7 8.0 7.0 1.5 1 1 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Ectatomin PF06457.6 ABX13023.1 - 0.024 14.3 0.9 0.054 13.1 0.6 1.6 1 0 0 1 1 1 0 Ectatomin TroA PF01297.12 ABX13024.1 - 2.1e-79 266.4 0.3 2.4e-79 266.2 0.2 1.0 1 0 0 1 1 1 1 Periplasmic solute binding protein family DUF3453 PF11935.3 ABX13024.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) YL1_C PF08265.6 ABX13024.1 - 0.15 11.6 0.3 0.28 10.7 0.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Cupredoxin_1 PF13473.1 ABX13025.1 - 0.0032 17.3 0.0 0.0098 15.7 0.0 1.9 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.15 ABX13025.1 - 0.018 15.2 0.8 0.07 13.3 0.0 2.2 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family Zip PF02535.17 ABX13026.1 - 3.5e-05 22.9 17.2 3.5e-05 22.9 11.9 2.6 1 1 1 2 2 2 2 ZIP Zinc transporter Cu-oxidase_3 PF07732.10 ABX13027.1 - 5.4e-24 84.1 5.3 2.6e-20 72.2 0.5 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 ABX13027.1 - 1.2e-18 66.8 7.9 3.3e-07 29.9 0.1 3.4 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.1 ABX13027.1 - 0.12 12.2 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Cupredoxin-like domain Fe_dep_repress PF01325.14 ABX13028.1 - 1.1e-21 76.4 0.1 1.9e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.10 ABX13028.1 - 1.2e-13 50.5 0.0 2.1e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain MarR_2 PF12802.2 ABX13028.1 - 3.3e-05 23.4 0.0 5.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 MarR family DUF4423 PF14394.1 ABX13028.1 - 0.00018 21.1 0.1 0.00029 20.4 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) HTH_Crp_2 PF13545.1 ABX13028.1 - 0.0007 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_45 PF14947.1 ABX13028.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.17 ABX13028.1 - 0.0015 18.2 0.0 0.0036 16.9 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 ABX13028.1 - 0.0021 18.3 0.0 0.0092 16.2 0.0 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.14 ABX13028.1 - 0.0033 17.0 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.4 ABX13028.1 - 0.0075 16.1 0.0 0.0075 16.1 0.0 1.7 2 1 0 2 2 1 1 Uncharacterized protein conserved in archaea (DUF2250) TFIIE_alpha PF02002.12 ABX13028.1 - 0.051 13.0 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 TFIIE alpha subunit LexA_DNA_bind PF01726.11 ABX13028.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 LexA DNA binding domain HTH_24 PF13412.1 ABX13028.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FeoC PF09012.5 ABX13028.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator Kelch_1 PF01344.20 ABX13029.1 - 2e-57 190.5 1.3 1.5e-12 46.8 0.0 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 ABX13029.1 - 5.6e-40 133.9 9.5 2e-09 37.2 0.0 7.0 4 2 3 7 7 7 5 Kelch motif Kelch_2 PF07646.10 ABX13029.1 - 6.2e-35 117.6 2.1 6.6e-08 32.0 0.0 6.5 7 0 0 7 7 7 6 Kelch motif Kelch_4 PF13418.1 ABX13029.1 - 1.5e-29 101.5 12.0 3.5e-07 29.8 0.0 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 ABX13029.1 - 3.5e-27 93.8 2.2 0.00087 19.1 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 ABX13029.1 - 2.4e-22 78.4 9.6 6.3e-05 23.0 0.0 7.1 7 1 0 7 7 7 4 Galactose oxidase, central domain PQQ_3 PF13570.1 ABX13029.1 - 5.7e-05 23.2 3.3 0.72 10.2 0.1 5.1 5 1 1 6 6 6 1 PQQ-like domain Rax2 PF12768.2 ABX13029.1 - 0.00011 21.5 0.1 0.017 14.3 0.0 2.1 1 1 1 2 2 2 2 Cortical protein marker for cell polarity Nop53 PF07767.6 ABX13029.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RNA_bind_2 PF10133.4 ABX13030.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Predicted RNA-binding protein Spermine_synth PF01564.12 ABX13031.1 - 3.4e-17 62.2 0.0 6.6e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_3 PF01596.12 ABX13031.1 - 8.4e-06 24.9 0.1 1.3e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_30 PF05430.6 ABX13031.1 - 0.00014 21.5 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 ABX13031.1 - 0.00018 22.0 0.0 0.00033 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 ABX13031.1 - 0.0049 17.6 0.0 0.01 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ABX13031.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 ABX13031.1 - 0.038 14.4 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 ABX13031.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Cu-oxidase_3 PF07732.10 ABX13032.1 - 4.3e-35 119.9 2.4 4e-33 113.6 0.1 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 ABX13032.1 - 1.4e-30 105.5 5.1 5.3e-23 81.0 0.7 3.8 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 ABX13032.1 - 8.1e-13 48.5 0.4 1.4e-06 28.3 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase SoxE PF06525.6 ABX13032.1 - 0.095 11.9 2.0 0.57 9.4 0.0 2.6 3 0 0 3 3 3 0 Sulfocyanin (SoxE) Ferric_reduct PF01794.14 ABX13034.1 - 8.8e-10 38.7 9.6 8.8e-10 38.7 6.7 2.5 2 1 1 3 3 3 2 Ferric reductase like transmembrane component DUF4293 PF14126.1 ABX13034.1 - 0.29 11.0 3.4 3.4 7.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Cation_ATPase_C PF00689.16 ABX13034.1 - 1.2 8.6 15.2 0.16 11.4 1.4 2.1 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Yip1 PF04893.12 ABX13035.1 - 0.033 13.6 3.3 0.04 13.4 2.3 1.0 1 0 0 1 1 1 0 Yip1 domain PMP22_Claudin PF00822.15 ABX13035.1 - 0.076 12.6 0.1 0.088 12.4 0.1 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Mem_trans PF03547.13 ABX13035.1 - 0.1 10.9 4.4 0.12 10.6 3.1 1.0 1 0 0 1 1 1 0 Membrane transport protein 7TMR-DISM_7TM PF07695.6 ABX13035.1 - 0.13 11.8 3.2 0.15 11.7 2.2 1.0 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF3099 PF11298.3 ABX13035.1 - 0.41 10.4 4.2 0.25 11.1 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Thioredoxin_4 PF13462.1 ABX13036.1 - 1e-24 87.3 0.0 1.3e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 ABX13036.1 - 5.9e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.1 ABX13036.1 - 0.002 17.7 0.1 0.0032 17.0 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Gly_radical PF01228.16 ABX13037.1 - 1.2 9.5 3.8 1.3 9.4 1.3 1.9 1 1 1 2 2 2 0 Glycine radical EthD PF07110.6 ABX13037.1 - 1.4 9.9 5.1 3 8.8 1.8 2.7 1 1 0 2 2 2 0 EthD domain Copper-bind PF00127.15 ABX13038.1 - 1.1e-06 28.7 0.0 1.6e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 ABX13038.1 - 0.00034 20.4 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain CbiM PF01891.11 ABX13038.1 - 0.062 12.8 0.4 0.082 12.4 0.3 1.1 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Thioredoxin_4 PF13462.1 ABX13039.1 - 9.8e-37 126.4 0.0 1.2e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 ABX13039.1 - 1e-13 51.2 0.0 1.4e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 ABX13039.1 - 3.9e-07 30.2 0.1 9.9e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 ABX13039.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 ABX13039.1 - 0.00016 21.7 0.1 0.0028 17.7 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 ABX13039.1 - 0.021 14.4 0.1 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin DsbD PF02683.10 ABX13040.1 - 3.2e-18 66.1 18.1 3.2e-18 66.1 12.5 2.1 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.1 ABX13040.1 - 3.7e-09 36.6 25.9 4.6e-09 36.3 15.8 2.2 1 1 1 2 2 2 2 Cytochrome C biogenesis protein transmembrane region DUF2182 PF09948.4 ABX13040.1 - 0.004 17.0 5.3 0.016 15.1 3.7 1.9 1 1 0 1 1 1 1 Predicted metal-binding integral membrane protein (DUF2182) DUF3953 PF13129.1 ABX13040.1 - 0.072 12.7 0.5 0.072 12.7 0.3 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3953) DUF872 PF05915.7 ABX13040.1 - 2.5 7.9 17.9 0.16 11.8 2.2 3.3 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Thioredoxin_3 PF13192.1 ABX13041.1 - 6.5e-15 54.7 0.3 6.5e-15 54.7 0.2 1.5 2 0 0 2 2 2 1 Thioredoxin domain Glutaredoxin PF00462.19 ABX13041.1 - 8e-11 41.7 0.2 1.3e-10 41.1 0.2 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 ABX13041.1 - 6.4e-05 23.1 0.0 7.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) ArsC PF03960.10 ABX13041.1 - 0.00012 22.1 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 ArsC family KaiB PF07689.7 ABX13041.1 - 0.0016 17.9 0.3 0.0056 16.1 0.0 1.9 1 1 1 2 2 2 1 KaiB domain GST_N_3 PF13417.1 ABX13041.1 - 0.0045 17.1 0.0 0.0063 16.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.15 ABX13041.1 - 0.0061 16.2 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ABX13041.1 - 0.051 13.7 0.4 0.27 11.4 0.2 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Trypsin_2 PF13365.1 ABX13042.1 - 2.1e-23 82.5 0.3 3.9e-23 81.7 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 ABX13042.1 - 3.9e-15 55.4 0.8 2.4e-14 52.9 0.2 2.4 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.21 ABX13042.1 - 5e-13 49.1 0.1 9.8e-13 48.1 0.1 1.5 1 1 0 1 1 1 1 Trypsin PDZ PF00595.19 ABX13042.1 - 0.0011 19.1 1.2 2.4 8.3 0.3 3.5 3 0 0 3 3 3 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S29 PF02907.10 ABX13042.1 - 0.0029 17.1 0.4 0.009 15.5 0.0 2.0 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.4 ABX13042.1 - 0.0065 14.9 2.0 0.018 13.4 0.4 1.9 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S32 PF05579.8 ABX13042.1 - 0.016 14.2 2.2 1.2 8.0 0.1 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 DUF31 PF01732.11 ABX13042.1 - 0.044 13.1 0.0 6 6.0 0.0 2.4 2 0 0 2 2 2 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.16 ABX13042.1 - 0.084 12.2 0.5 0.22 10.9 0.4 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease HTH_AsnC-type PF13404.1 ABX13043.1 - 2e-13 49.6 0.2 2.8e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 ABX13043.1 - 1.2e-11 43.8 0.4 2.1e-11 43.0 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Arc_trans_TRASH PF08394.5 ABX13043.1 - 5.4e-07 29.6 5.2 9.4e-07 28.8 3.6 1.4 1 0 0 1 1 1 1 Archaeal TRASH domain TrmB PF01978.14 ABX13043.1 - 0.00027 20.6 0.0 0.00079 19.0 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 ABX13043.1 - 0.0011 18.5 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_23 PF13384.1 ABX13043.1 - 0.0021 17.6 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain DUF2250 PF10007.4 ABX13043.1 - 0.003 17.4 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) FeoC PF09012.5 ABX13043.1 - 0.0055 16.3 0.2 0.0055 16.3 0.2 2.2 1 1 1 2 2 2 1 FeoC like transcriptional regulator HTH_28 PF13518.1 ABX13043.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 ABX13043.1 - 0.009 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.1 ABX13043.1 - 0.0098 15.4 0.2 0.025 14.0 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 ABX13043.1 - 0.017 14.6 0.0 0.042 13.2 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 ATPase-cat_bd PF12156.3 ABX13043.1 - 0.019 15.4 2.4 0.05 14.1 1.4 1.9 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase MarR_2 PF12802.2 ABX13043.1 - 0.044 13.4 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_psq PF05225.11 ABX13043.1 - 0.054 13.0 0.2 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_20 PF12840.2 ABX13043.1 - 0.056 13.2 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.5 ABX13043.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR PF01047.17 ABX13043.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.1 ABX13043.1 - 0.15 12.4 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain Thioredoxin_4 PF13462.1 ABX13044.1 - 2.1e-40 138.4 0.0 2.7e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 ABX13044.1 - 1.1e-19 70.7 0.1 2.8e-10 40.0 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 ABX13044.1 - 4.9e-09 36.3 0.0 1.4e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 ABX13044.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.1 ABX13046.1 - 1.2e-40 139.2 0.0 1.5e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 ABX13046.1 - 5.3e-14 52.2 0.2 5e-12 45.7 0.1 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 ABX13046.1 - 0.0012 18.9 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 ABX13046.1 - 0.016 14.7 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF3892 PF13031.1 ABX13047.1 - 4.2e-06 27.0 0.0 5.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3892) DUF1533 PF07550.6 ABX13047.1 - 0.0027 17.6 1.1 0.0065 16.4 0.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1533) Gemin6 PF06372.7 ABX13047.1 - 0.025 13.9 0.2 0.032 13.5 0.1 1.2 1 0 0 1 1 1 0 Gemin6 protein DUF1853 PF08907.6 ABX13047.1 - 0.12 11.4 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1853) TrmB PF01978.14 ABX13048.1 - 6.4e-06 25.7 0.1 1e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 ABX13048.1 - 0.006 16.2 0.4 0.0096 15.5 0.3 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 ABX13048.1 - 0.0073 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.7 ABX13048.1 - 0.014 15.0 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 HTH domain B-block_TFIIIC PF04182.7 ABX13048.1 - 0.039 13.8 0.7 0.085 12.7 0.5 1.7 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC Mga PF05043.8 ABX13048.1 - 0.04 14.2 2.0 0.31 11.3 0.2 2.1 1 1 1 2 2 2 0 Mga helix-turn-helix domain HTH_23 PF13384.1 ABX13048.1 - 0.053 13.1 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.1 ABX13048.1 - 0.071 12.5 0.5 0.17 11.3 0.1 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TFIIE_alpha PF02002.12 ABX13048.1 - 0.089 12.3 0.1 0.096 12.2 0.0 1.3 1 1 0 1 1 1 0 TFIIE alpha subunit Sigma70_r4_2 PF08281.7 ABX13048.1 - 0.12 11.8 0.1 0.21 11.0 0.0 1.4 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_IclR PF09339.5 ABX13048.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain NicO PF03824.11 ABX13049.1 - 2.3e-11 43.5 18.4 7.5e-11 41.8 12.8 1.7 1 1 0 1 1 1 1 High-affinity nickel-transport protein DsbD_2 PF13386.1 ABX13049.1 - 5e-06 26.4 9.9 3e-05 23.8 5.9 2.3 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region DUF1469 PF07332.6 ABX13049.1 - 0.016 14.9 5.4 0.058 13.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) OGFr_N PF04664.8 ABX13049.1 - 0.041 13.1 0.3 0.06 12.6 0.2 1.2 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region MethyTransf_Reg PF10119.4 ABX13050.1 - 0.31 11.5 5.9 12 6.4 0.1 4.4 4 1 1 5 5 5 0 Predicted methyltransferase regulatory domain Yip1 PF04893.12 ABX13050.1 - 0.66 9.4 0.0 0.66 9.4 0.0 2.4 3 0 0 3 3 3 0 Yip1 domain HTH_5 PF01022.15 ABX13051.1 - 4.8e-18 64.5 0.3 7.6e-18 63.9 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 ABX13051.1 - 7.7e-10 38.4 0.0 1.2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 ABX13051.1 - 1.4e-07 31.1 0.0 2.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 ABX13051.1 - 2.5e-06 27.0 0.0 3.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.5 ABX13051.1 - 3.4e-05 23.3 0.0 6.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_27 PF13463.1 ABX13051.1 - 4.7e-05 23.6 0.0 8.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.17 ABX13051.1 - 0.00015 21.4 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 MarR family DUF4423 PF14394.1 ABX13051.1 - 0.00031 20.3 0.0 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_34 PF13601.1 ABX13051.1 - 0.00036 20.5 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_45 PF14947.1 ABX13051.1 - 0.00067 19.4 0.4 0.0017 18.1 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix Fe_dep_repress PF01325.14 ABX13051.1 - 0.0013 18.6 0.1 0.0036 17.2 0.0 1.8 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.1 ABX13051.1 - 0.0015 17.8 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 ABX13051.1 - 0.0059 16.7 0.0 0.0096 16.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator GerE PF00196.14 ABX13051.1 - 0.012 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Penicillinase_R PF03965.11 ABX13051.1 - 0.032 14.3 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor HTH_37 PF13744.1 ABX13051.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.7 2 1 0 2 2 1 0 Helix-turn-helix domain HTH_9 PF08221.6 ABX13051.1 - 0.071 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 ABX13051.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 TFIIE alpha subunit HTH_29 PF13551.1 ABX13051.1 - 0.096 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix DUF2172 PF09940.4 ABX13051.1 - 0.1 10.9 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) PqqD PF05402.7 ABX13051.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) HrcA_DNA-bdg PF03444.10 ABX13051.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_1 PF00126.22 ABX13051.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Cation_efflux PF01545.16 ABX13052.1 - 5.2e-19 68.4 13.2 9.9e-18 64.2 9.1 1.9 1 1 0 1 1 1 1 Cation efflux family DUF998 PF06197.8 ABX13052.1 - 0.082 12.2 17.1 0.21 10.9 6.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF998) MrpF_PhaF PF04066.8 ABX13052.1 - 0.14 12.4 3.4 6.3 7.1 0.3 3.0 2 1 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) DUF3188 PF11384.3 ABX13052.1 - 4.2 7.0 10.8 2.2 7.9 0.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3188) DUF4433 PF14487.1 ABX13054.1 - 1.9e-46 158.4 0.4 2.8e-46 157.8 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4433) Macro PF01661.16 ABX13054.1 - 1.4e-08 34.6 0.0 3.6e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Macro domain Cons_hypoth95 PF03602.10 ABX13055.1 - 0.046 13.1 0.0 6.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Gp37_Gp68 PF07505.6 ABX13056.1 - 5.1e-84 281.5 0.7 7.7e-84 280.9 0.5 1.1 1 0 0 1 1 1 1 Phage protein Gp37/Gp68 Syd PF07348.7 ABX13057.1 - 0.005 16.1 1.2 0.0072 15.6 0.1 1.7 2 0 0 2 2 2 1 Syd protein (SUKH-2) Na_trans_assoc PF06512.8 ABX13057.1 - 3.1 7.7 9.3 0.35 10.7 1.0 2.4 2 1 0 2 2 2 0 Sodium ion transport-associated GIY-YIG PF01541.19 ABX13058.1 - 3.1e-06 27.4 3.0 4e-06 27.1 2.1 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain FAM177 PF14774.1 ABX13058.1 - 0.043 13.7 0.3 0.075 12.9 0.0 1.5 2 0 0 2 2 2 0 FAM177 family Seipin PF06775.9 ABX13058.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) DUF3360 PF11840.3 ABX13059.1 - 1 7.5 5.0 1.1 7.5 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) DUF456 PF04306.8 ABX13060.1 - 0.021 14.8 1.1 0.026 14.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF1269 PF06897.7 ABX13060.1 - 0.12 12.4 7.0 0.65 10.0 3.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) Rick_17kDa_Anti PF05433.10 ABX13060.1 - 1.4 8.6 16.3 2.7 7.7 11.3 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 ABX13060.1 - 1.6 8.2 15.0 2.7 7.5 10.4 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 ABX13060.1 - 4.2 7.5 10.1 7.2 6.8 7.0 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide MT-A70 PF05063.9 ABX13061.1 - 3.6e-30 104.8 0.0 1.1e-29 103.1 0.0 1.8 2 0 0 2 2 2 1 MT-A70 N6_N4_Mtase PF01555.13 ABX13061.1 - 0.025 14.0 0.1 0.041 13.3 0.0 1.4 1 1 0 1 1 1 0 DNA methylase ParBc PF02195.13 ABX13062.1 - 3.3e-12 46.3 0.0 3.7e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_DeoR PF08220.7 ABX13063.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain DZR PF12773.2 ABX13063.1 - 0.087 12.6 2.1 0.17 11.7 1.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon Penicillinase_R PF03965.11 ABX13064.1 - 0.0058 16.7 0.1 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Penicillinase repressor RNA_polI_A14 PF08203.6 ABX13064.1 - 0.15 12.3 0.7 0.33 11.2 0.5 1.6 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Phage_integrase PF00589.17 ABX13065.1 - 4.2e-05 23.2 0.3 0.017 14.7 0.0 2.7 3 0 0 3 3 3 2 Phage integrase family FadA PF09403.5 ABX13065.1 - 0.27 11.2 3.7 0.78 9.7 2.6 1.7 1 0 0 1 1 1 0 Adhesion protein FadA Flavodoxin_2 PF02525.12 ABX13066.1 - 2.4e-30 105.5 0.0 3.4e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 ABX13066.1 - 5.6e-06 25.9 0.0 3e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Osmo_CC PF08946.5 ABX13066.1 - 0.00039 20.3 0.8 0.00069 19.5 0.5 1.4 1 0 0 1 1 1 1 Osmosensory transporter coiled coil Flavodoxin_4 PF12682.2 ABX13066.1 - 0.0015 17.9 0.2 0.0021 17.4 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin Cna_B PF05738.8 ABX13066.1 - 0.051 13.3 0.1 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Cna protein B-type domain DUF393 PF04134.7 ABX13067.1 - 0.00044 21.3 0.0 0.00054 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Kazal_2 PF07648.10 ABX13067.1 - 0.12 12.2 0.3 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain VKG_Carbox PF05090.9 ABX13068.1 - 7.7e-116 387.5 32.4 1.4e-114 383.4 22.5 1.9 1 1 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase zf-dskA_traR PF01258.12 ABX13069.1 - 0.068 12.9 0.2 0.093 12.4 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger C1_1 PF00130.17 ABX13069.1 - 0.17 11.6 0.5 0.37 10.5 0.4 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4179 PF13786.1 ABX13070.1 - 0.064 13.4 0.3 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Pyrophosphatase PF00719.14 ABX13071.1 - 3.1e-59 198.9 0.1 3.5e-59 198.7 0.1 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase zf-UBP PF02148.14 ABX13072.1 - 1.6e-12 47.3 8.8 2.8e-12 46.5 6.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein FYVE PF01363.16 ABX13072.1 - 0.48 10.3 7.9 0.86 9.5 5.4 1.5 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_UBOX PF13445.1 ABX13072.1 - 6.8 6.4 11.0 1 9.1 3.2 2.6 3 1 0 3 3 3 0 RING-type zinc-finger Peptidase_M3 PF01432.15 ABX13073.1 - 1.8e-44 152.5 0.3 8.2e-44 150.3 0.2 2.0 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.5 ABX13073.1 - 1.1e-06 28.6 0.1 1.1e-06 28.6 0.1 3.2 3 0 0 3 3 3 1 Oligopeptidase F DUF955 PF06114.8 ABX13073.1 - 0.0032 17.1 0.1 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF955) Peptidase_MA_2 PF13485.1 ABX13073.1 - 0.021 14.8 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily DUF892 PF05974.7 ABX13073.1 - 0.033 14.0 0.2 0.078 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF892) NPV_P10 PF05531.7 ABX13073.1 - 0.077 13.2 2.2 0.18 12.0 0.2 2.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ArsC PF03960.10 ABX13073.1 - 0.13 12.3 3.5 2.6 8.1 1.4 3.3 3 0 0 3 3 3 0 ArsC family DUF2762 PF10960.3 ABX13073.1 - 0.31 10.7 4.7 4.5 7.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) DUF4231 PF14015.1 ABX13074.1 - 3.9 7.5 9.3 31 4.6 6.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF2157 PF09925.4 ABX13074.1 - 5.1 6.6 8.5 0.16 11.5 1.6 1.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF771 PF05595.6 ABX13075.1 - 0.099 12.5 0.1 0.37 10.7 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF771) PvlArgDC PF01862.11 ABX13076.1 - 3.9e-63 211.9 0.0 4.3e-63 211.8 0.0 1.0 1 0 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Thioredoxin_4 PF13462.1 ABX13077.1 - 1e-43 149.1 0.1 1.8e-43 148.3 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.15 ABX13077.1 - 3.8e-19 68.9 0.5 3.4e-17 62.6 0.4 2.2 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 ABX13077.1 - 3e-08 33.8 0.0 6.9e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 ABX13077.1 - 0.00017 21.2 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin CEP19 PF14933.1 ABX13077.1 - 0.081 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 CEP19-like protein DUF682 PF05081.7 ABX13077.1 - 0.12 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF682) DEAD PF00270.24 ABX13078.1 - 2.2e-47 160.6 0.1 5.9e-45 152.7 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 ABX13078.1 - 1.3e-26 92.2 0.0 2.8e-25 87.9 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 ABX13078.1 - 0.0015 17.3 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_30 PF13604.1 ABX13078.1 - 0.0021 17.6 0.1 0.0077 15.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 ABX13078.1 - 0.0094 15.0 0.4 0.031 13.3 0.1 1.9 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 ABX13078.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain ResIII PF04851.10 ABX13078.1 - 0.035 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AsnC_trans_reg PF01037.16 ABX13079.1 - 6.8e-06 25.6 0.1 7.1e-06 25.6 0.1 1.0 1 0 0 1 1 1 1 AsnC family GYD PF08734.6 ABX13079.1 - 0.00027 20.6 0.0 0.00031 20.4 0.0 1.1 1 0 0 1 1 1 1 GYD domain DUF3139 PF11337.3 ABX13081.1 - 0.015 15.5 2.3 0.039 14.2 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) Vps5 PF09325.5 ABX13081.1 - 0.016 14.4 0.8 0.016 14.4 0.5 1.8 2 0 0 2 2 2 0 Vps5 C terminal like DUF1474 PF07342.6 ABX13081.1 - 0.038 14.2 1.1 0.13 12.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Imm10 PF15562.1 ABX13081.1 - 0.049 13.3 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 10 DUF3426 PF11906.3 ABX13082.1 - 5.4e-11 42.3 0.3 8.4e-06 25.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3426) DUF2393 PF09624.5 ABX13082.1 - 0.0021 17.6 0.1 0.0021 17.6 0.1 2.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2393) DUF3157 PF11355.3 ABX13082.1 - 0.006 15.8 0.5 0.97 8.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3157) DUF4352 PF11611.3 ABX13082.1 - 0.46 10.6 3.3 0.33 11.1 0.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4352) Laminin_II PF06009.7 ABX13083.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Laminin Domain II zf-ribbon_3 PF13248.1 ABX13084.1 - 5.8e-06 25.3 0.6 1.1e-05 24.4 0.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 ABX13084.1 - 3e-05 23.3 0.7 9e-05 21.8 0.5 1.9 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 ABX13084.1 - 4.9e-05 23.0 0.3 0.00013 21.6 0.2 1.7 1 0 0 1 1 1 1 Double zinc ribbon CBM_14 PF01607.19 ABX13084.1 - 6.5e-05 22.7 2.2 4.2 7.3 0.0 3.4 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain DUF4448 PF14610.1 ABX13084.1 - 0.00025 20.5 0.2 0.008 15.6 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF4448) Pro_Al_protease PF02983.9 ABX13084.1 - 0.00052 19.9 0.0 4.1 7.4 0.0 3.2 1 1 2 3 3 3 2 Alpha-lytic protease prodomain DEAD_2 PF06733.10 ABX13084.1 - 0.025 13.9 3.0 0.18 11.2 0.7 2.5 1 1 1 2 2 2 0 DEAD_2 Pectate_lyase PF03211.8 ABX13084.1 - 0.034 13.5 0.8 1 8.6 0.1 2.5 1 1 2 3 3 3 0 Pectate lyase zf-DHHC PF01529.15 ABX13084.1 - 0.071 12.4 0.4 0.23 10.8 0.2 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF4480 PF13715.1 ABX13084.1 - 0.29 11.2 2.1 90 3.2 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4480) Candida_ALS PF05792.8 ABX13084.1 - 0.37 10.9 3.5 61 3.8 0.0 3.2 3 0 0 3 3 3 0 Candida agglutinin-like (ALS) DUF916 PF06030.7 ABX13086.1 - 0.056 13.2 0.4 0.073 12.8 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) Thioredox_DsbH PF03190.10 ABX13087.1 - 2.5e-77 258.2 0.1 4.2e-77 257.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 ABX13087.1 - 3.9e-15 55.6 0.0 8.2e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.8 ABX13087.1 - 2.5e-07 30.1 1.1 0.078 12.2 0.1 4.1 3 1 1 4 4 4 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.8 ABX13087.1 - 4.3e-05 22.7 0.0 0.16 10.9 0.0 2.8 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 Thioredoxin_2 PF13098.1 ABX13087.1 - 7.9e-05 22.8 0.1 0.00027 21.0 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain LANC_like PF05147.8 ABX13087.1 - 0.0011 17.5 2.3 6.6 5.1 0.0 4.8 4 1 0 5 5 5 2 Lanthionine synthetase C-like protein GlcNAc_2-epim PF07221.6 ABX13087.1 - 0.0018 17.3 0.0 1 8.2 0.0 2.9 2 1 1 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF1680 PF07944.7 ABX13087.1 - 0.0067 14.7 0.0 0.087 11.0 0.0 2.6 1 1 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) DUF2838 PF10998.3 ABX13087.1 - 0.038 13.8 0.2 0.17 11.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) Glyco_hydro_76 PF03663.9 ABX13087.1 - 0.1 11.9 0.0 0.87 8.9 0.0 2.3 2 1 0 2 2 2 0 Glycosyl hydrolase family 76 DUF2951 PF11166.3 ABX13088.1 - 0.053 13.3 1.1 0.06 13.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) ADH_N PF08240.7 ABX13089.1 - 3.1e-31 107.3 1.3 6.1e-31 106.4 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ABX13089.1 - 4.9e-19 68.1 0.3 7.4e-19 67.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ABX13089.1 - 0.00016 20.9 0.0 0.00036 19.7 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 ABX13089.1 - 0.0077 17.1 0.0 0.015 16.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 ABX13089.1 - 0.009 15.8 0.2 0.016 15.0 0.2 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 ABX13089.1 - 0.014 15.8 1.2 0.048 14.1 0.1 2.1 1 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_10 PF13460.1 ABX13089.1 - 0.023 14.7 0.1 0.049 13.6 0.1 1.7 1 0 0 1 1 1 0 NADH(P)-binding CoA_binding PF02629.14 ABX13089.1 - 0.024 15.1 6.1 0.095 13.2 2.2 3.1 2 1 1 3 3 3 0 CoA binding domain Utp12 PF04003.7 ABX13089.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family Zn_Tnp_IS1595 PF12760.2 ABX13090.1 - 0.00045 19.9 2.9 0.0011 18.6 2.0 1.6 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-TFIIB PF13453.1 ABX13090.1 - 0.015 14.4 5.0 0.037 13.2 2.7 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger OrfB_Zn_ribbon PF07282.6 ABX13090.1 - 0.036 13.7 3.1 0.069 12.8 2.1 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Cys_rich_CPCC PF14206.1 ABX13090.1 - 0.17 11.4 1.4 0.35 10.4 1.0 1.5 1 0 0 1 1 1 0 Cysteine-rich CPCC Rad50_zn_hook PF04423.9 ABX13090.1 - 0.33 10.4 5.5 0.83 9.1 1.4 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif Desulfoferrod_N PF06397.7 ABX13090.1 - 0.7 9.3 4.1 11 5.5 0.1 2.8 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Zn-ribbon_8 PF09723.5 ABX13090.1 - 2.8 7.9 7.3 23 5.0 1.6 2.4 1 1 0 2 2 2 0 Zinc ribbon domain ThiF PF00899.16 ABX13091.1 - 0.061 13.1 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 ThiF family Plus-3 PF03126.13 ABX13091.1 - 0.13 12.2 0.1 0.15 12.1 0.1 1.3 1 1 0 1 1 1 0 Plus-3 domain AsnC_trans_reg PF01037.16 ABX13093.1 - 3.5e-10 39.4 0.1 3.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 AsnC family GYD PF08734.6 ABX13093.1 - 0.00029 20.5 0.0 0.00038 20.1 0.0 1.1 1 0 0 1 1 1 1 GYD domain DUF2338 PF10100.4 ABX13093.1 - 0.074 11.4 0.1 0.084 11.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) TruD PF01142.13 ABX13094.1 - 7e-63 212.5 0.4 8.2e-63 212.3 0.3 1.1 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) SGL PF08450.7 ABX13095.1 - 6.2e-08 32.3 3.8 0.0066 15.8 0.0 4.7 4 2 2 6 6 6 2 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 ABX13095.1 - 0.0017 18.1 7.3 3.7 7.9 0.2 5.3 5 0 0 5 5 5 2 Two component regulator propeller PTH2 PF01981.11 ABX13096.1 - 6.5e-44 148.3 0.1 7.3e-44 148.1 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Response_reg PF00072.19 ABX13098.1 - 3.5e-22 78.5 1.1 4e-22 78.3 0.8 1.0 1 0 0 1 1 1 1 Response regulator receiver domain NUMOD4 PF07463.6 ABX13100.1 - 0.041 13.7 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 NUMOD4 motif 7TM-7TMR_HD PF07698.6 ABX13100.1 - 0.048 13.1 0.2 0.048 13.1 0.2 1.8 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase dDENN PF03455.14 ABX13101.1 - 0.0072 16.3 0.6 0.021 14.9 0.4 1.7 1 0 0 1 1 1 1 dDENN domain Response_reg PF00072.19 ABX13102.1 - 4.9e-22 78.0 0.7 5.8e-22 77.8 0.5 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 ABX13103.1 - 4.4e-19 68.2 0.0 9.8e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.20 ABX13103.1 - 1.7e-11 44.1 0.0 7.3e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.20 ABX13103.1 - 1.2e-09 38.0 0.0 3.6e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 ABX13103.1 - 4.7e-08 32.6 0.2 9.7e-07 28.4 0.0 2.8 2 0 0 2 2 2 1 GHKL domain Cache_1 PF02743.13 ABX13103.1 - 0.00016 21.1 0.0 0.00035 20.0 0.0 1.6 1 0 0 1 1 1 1 Cache domain GRP PF07172.6 ABX13104.1 - 0.024 15.0 0.0 0.033 14.6 0.0 1.2 1 0 0 1 1 1 0 Glycine rich protein family HD PF01966.17 ABX13106.1 - 5.9e-15 55.3 0.3 1.9e-14 53.7 0.1 1.9 2 0 0 2 2 2 1 HD domain HDOD PF08668.7 ABX13106.1 - 0.0003 20.1 0.0 0.00062 19.1 0.0 1.4 1 0 0 1 1 1 1 HDOD domain Type_III_YscX PF09474.5 ABX13107.1 - 0.032 14.2 0.0 0.06 13.3 0.0 1.4 1 1 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) PASTA PF03793.14 ABX13107.1 - 0.046 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 PASTA domain Metallophos PF00149.23 ABX13108.1 - 3.9e-17 62.2 0.8 1.1e-16 60.8 0.6 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ABX13108.1 - 1.2e-12 47.9 0.1 1.9e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_23 PF13476.1 ABX13109.1 - 3.4e-16 60.1 20.7 3.4e-16 60.1 14.4 5.9 1 1 4 5 5 5 1 AAA domain AAA_29 PF13555.1 ABX13109.1 - 6.3e-07 28.8 0.0 1.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 ABX13109.1 - 0.011 14.2 0.2 0.011 14.2 0.2 4.9 2 1 2 4 4 4 0 AAA domain CbiA PF01656.18 ABX13110.1 - 1.3e-23 83.4 0.0 1.8e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 ABX13110.1 - 5.4e-08 32.9 0.1 0.0031 17.4 0.0 2.6 3 0 0 3 3 3 2 AAA domain ArsA_ATPase PF02374.10 ABX13110.1 - 1.6e-07 30.6 0.0 2.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase MipZ PF09140.6 ABX13110.1 - 2.3e-06 26.8 0.0 1.3e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ YhjQ PF06564.7 ABX13110.1 - 4e-06 26.3 0.0 9.7e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 YhjQ protein Fer4_NifH PF00142.13 ABX13110.1 - 1e-05 24.8 0.1 3e-05 23.3 0.0 1.8 3 0 0 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 ABX13110.1 - 0.0088 15.1 0.0 0.26 10.3 0.0 2.1 2 0 0 2 2 2 1 VirC1 protein Iron_traffic PF04362.9 ABX13110.1 - 0.016 14.5 0.6 0.034 13.5 0.2 1.6 1 1 0 1 1 1 0 Bacterial Fe(2+) trafficking ATP_bind_1 PF03029.12 ABX13110.1 - 0.019 14.5 0.1 0.04 13.4 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.17 ABX13110.1 - 0.024 14.0 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ArgK PF03308.11 ABX13110.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein DUF4508 PF14969.1 ABX13110.1 - 0.55 10.2 3.8 2.8 7.9 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4508) FAST_1 PF06743.10 ABX13111.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 DUF3921 PF13060.1 ABX13112.1 - 0.00039 20.2 1.5 0.0063 16.3 0.4 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3921) HTH_26 PF13443.1 ABX13112.1 - 0.0044 17.1 2.0 6.4 7.0 0.0 4.1 3 1 0 3 3 3 1 Cro/C1-type HTH DNA-binding domain ATP-synt_B PF00430.13 ABX13112.1 - 0.0083 15.9 3.8 0.0083 15.9 2.6 3.0 3 1 0 3 3 3 1 ATP synthase B/B' CF(0) DUF3349 PF11829.3 ABX13112.1 - 0.01 16.2 2.1 0.31 11.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3349) VitK2_biosynth PF02621.9 ABX13112.1 - 0.043 13.0 0.3 0.45 9.6 0.0 2.5 2 0 0 2 2 2 0 Menaquinone biosynthesis HTH_23 PF13384.1 ABX13112.1 - 0.092 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_19 PF12844.2 ABX13112.1 - 0.35 10.9 7.7 0.81 9.7 0.0 3.8 5 0 0 5 5 5 0 Helix-turn-helix domain DUF2877 PF11392.3 ABX13112.1 - 2 8.6 5.3 11 6.2 0.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2877) Acetyltransf_11 PF13720.1 ABX13112.1 - 5.2 7.3 8.3 29 4.9 0.0 4.2 5 1 1 6 6 6 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 SRP_SPB PF02978.14 ABX13112.1 - 5.7 7.2 8.3 6.3 7.0 0.9 3.9 3 1 1 5 5 5 0 Signal peptide binding domain PWI PF01480.12 ABX13114.1 - 0.16 12.1 2.3 0.61 10.2 0.0 2.9 3 1 0 3 3 3 0 PWI domain Phage_integrase PF00589.17 ABX13115.1 - 2.3e-06 27.3 1.3 1.5e-05 24.7 0.9 2.0 1 1 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.1 ABX13115.1 - 0.0032 17.7 0.0 0.015 15.6 0.0 2.0 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.12 ABX13115.1 - 0.034 14.3 0.4 0.29 11.2 0.0 2.6 3 1 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain ATP-cone PF03477.11 ABX13115.1 - 0.079 13.3 0.0 3.1 8.3 0.0 2.5 2 0 0 2 2 2 0 ATP cone domain Lycopene_cycl PF05834.7 ABX13116.1 - 1.6e-07 30.5 0.0 3.5e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.14 ABX13116.1 - 1.7e-07 30.6 2.1 0.018 14.0 0.0 3.0 1 1 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 ABX13116.1 - 7.8e-06 25.2 0.1 6.4e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ABX13116.1 - 5.8e-05 21.7 1.1 0.0016 16.9 0.1 2.4 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 ABX13116.1 - 6e-05 22.1 3.3 0.0068 15.3 1.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 ABX13116.1 - 0.00012 21.2 0.7 0.00023 20.3 0.2 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 ABX13116.1 - 0.00039 20.3 0.5 0.0043 17.0 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ABX13116.1 - 0.00044 19.2 0.8 0.00085 18.2 0.5 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ABX13116.1 - 0.00079 19.3 0.2 0.0027 17.6 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ABX13116.1 - 0.022 13.3 1.0 1.8 7.1 0.0 2.9 2 1 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.22 ABX13116.1 - 0.74 10.2 6.4 24 5.3 0.4 3.7 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase zf-HIT PF04438.11 ABX13117.1 - 0.0034 16.9 11.3 0.017 14.7 3.6 2.3 2 1 0 2 2 2 1 HIT zinc finger PolC_DP2 PF03833.8 ABX13117.1 - 0.015 13.0 6.1 0.016 12.8 4.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.2 ABX13117.1 - 0.046 13.5 10.3 0.18 11.6 7.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 ABX13117.1 - 0.048 13.4 12.3 0.075 12.8 8.5 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.1 ABX13117.1 - 0.12 12.5 4.1 0.15 12.3 2.8 1.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF1610 PF07754.6 ABX13117.1 - 0.18 11.9 14.7 0.63 10.2 1.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.1 ABX13117.1 - 0.27 10.4 8.2 0.73 9.1 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-B_box PF00643.19 ABX13117.1 - 0.56 10.1 10.8 0.66 9.9 2.2 2.1 1 1 1 2 2 2 0 B-box zinc finger zinc-ribbons_6 PF07191.7 ABX13117.1 - 0.59 9.9 8.2 1.1 9.0 5.7 1.5 1 1 0 1 1 1 0 zinc-ribbons A2L_zn_ribbon PF08792.5 ABX13117.1 - 0.6 9.6 11.1 2.5 7.6 0.3 3.1 2 1 1 3 3 3 0 A2L zinc ribbon domain DUF1272 PF06906.6 ABX13117.1 - 0.62 9.9 7.4 1.3 8.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-trcl PF13451.1 ABX13117.1 - 0.67 9.6 16.0 0.51 10.0 0.7 3.0 2 1 1 3 3 3 0 Probable zinc-binding domain ZZ PF00569.12 ABX13117.1 - 0.7 9.4 10.0 2.7 7.5 7.0 1.9 1 1 0 1 1 1 0 Zinc finger, ZZ type zf-Mss51 PF13824.1 ABX13117.1 - 0.72 9.7 9.3 0.52 10.2 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2 PF00096.21 ABX13117.1 - 0.96 9.9 7.2 12 6.4 0.2 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Elf1 PF05129.8 ABX13117.1 - 1 9.1 7.0 1.7 8.4 4.9 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF2296 PF10058.4 ABX13117.1 - 1.1 9.0 11.3 5.1 6.9 0.2 3.0 1 1 2 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zf-C4_Topoisom PF01396.14 ABX13117.1 - 1.2 8.7 6.5 0.31 10.5 0.8 2.4 1 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger C1_3 PF07649.7 ABX13117.1 - 1.4 8.9 7.9 1.9 8.6 1.4 2.2 2 0 0 2 2 2 0 C1-like domain zf-UBR PF02207.15 ABX13117.1 - 1.6 8.5 11.0 6 6.6 7.6 1.8 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Prok-RING_2 PF14445.1 ABX13117.1 - 1.6 8.7 9.6 22 5.0 6.9 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 TerY-C PF15616.1 ABX13117.1 - 1.7 8.5 8.6 2 8.3 6.0 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain UPF0547 PF10571.4 ABX13117.1 - 2.5 7.8 6.9 11 5.7 4.8 2.1 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 TF_Zn_Ribbon PF08271.7 ABX13117.1 - 3.4 7.0 7.7 10 5.5 5.3 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding Nudix_N_2 PF14803.1 ABX13117.1 - 3.5 7.4 8.6 16 5.2 6.0 2.4 1 1 0 1 1 1 0 Nudix N-terminal Rubredoxin PF00301.15 ABX13117.1 - 5.2 7.0 11.8 1.9 8.3 0.7 3.0 2 1 1 3 3 3 0 Rubredoxin DNA_ligase_ZBD PF03119.11 ABX13117.1 - 5.4 6.8 7.8 0.39 10.4 0.8 2.5 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Ribosomal_L37ae PF01780.14 ABX13117.1 - 5.7 6.8 9.1 89 3.0 6.3 2.5 1 1 0 1 1 1 0 Ribosomal L37ae protein family Tnp_zf-ribbon_2 PF13842.1 ABX13117.1 - 6 7.3 12.0 11 6.5 4.4 2.3 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zinc_ribbon_2 PF13240.1 ABX13117.1 - 7.7 6.1 11.5 0.59 9.6 0.8 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-AN1 PF01428.11 ABX13117.1 - 8.7 6.3 10.5 10 6.1 0.4 2.4 2 1 0 2 2 2 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.5 ABX13117.1 - 9.6 6.2 13.0 5.5 7.0 0.5 3.1 1 1 0 2 2 2 0 Zinc ribbon domain EF1_GNE PF00736.14 ABX13118.1 - 3.2e-22 78.0 0.1 3.5e-22 77.9 0.1 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain AAA PF00004.24 ABX13119.1 - 2.5e-89 296.2 0.0 3.5e-47 159.8 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 ABX13119.1 - 1.5e-24 85.6 0.7 6.7e-24 83.6 0.5 2.2 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 ABX13119.1 - 2e-14 53.2 0.0 1.8e-08 33.7 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 ABX13119.1 - 1.1e-12 48.2 0.0 2.8e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 ABX13119.1 - 2.6e-12 47.0 0.4 0.0027 17.8 0.0 4.5 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 ABX13119.1 - 7.8e-12 45.5 0.0 0.00036 20.5 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 ABX13119.1 - 1.2e-11 44.6 0.0 1e-06 28.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 ABX13119.1 - 9.7e-11 41.5 0.1 4.9e-05 23.0 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 ABX13119.1 - 3.5e-10 39.9 0.0 0.00025 20.8 0.0 3.6 2 1 1 3 3 3 2 Archaeal ATPase AAA_17 PF13207.1 ABX13119.1 - 4.4e-10 40.4 0.3 0.0019 18.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 ABX13119.1 - 7.1e-10 38.3 1.7 1.3e-09 37.5 0.4 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.1 ABX13119.1 - 3.5e-09 36.6 0.0 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 ABX13119.1 - 1.2e-08 35.0 0.0 0.0022 18.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 ABX13119.1 - 6.5e-08 32.9 0.0 0.031 14.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 ABX13119.1 - 1.9e-07 30.6 5.1 0.31 10.3 0.0 4.5 2 2 0 4 4 4 3 AAA domain AAA_28 PF13521.1 ABX13119.1 - 6.6e-07 29.4 0.0 0.035 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 ABX13119.1 - 8.1e-07 28.6 0.0 0.039 13.3 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein ABC_tran PF00005.22 ABX13119.1 - 1.1e-06 29.0 0.0 0.026 14.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter Sigma54_activ_2 PF14532.1 ABX13119.1 - 1.5e-06 28.3 0.0 0.018 15.1 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 ABX13119.1 - 2.3e-06 26.8 0.1 0.023 13.8 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin KaiC PF06745.8 ABX13119.1 - 4.1e-06 26.0 0.6 0.14 11.2 0.0 3.5 2 1 1 3 3 3 2 KaiC Mg_chelatase PF01078.16 ABX13119.1 - 9.8e-06 24.8 0.9 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 ABX13119.1 - 1.3e-05 24.9 0.4 0.38 10.3 0.0 3.7 4 0 0 4 4 3 1 NACHT domain AAA_24 PF13479.1 ABX13119.1 - 3.5e-05 23.4 1.7 0.23 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 ABX13119.1 - 8e-05 22.3 0.2 0.17 11.6 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain TIP49 PF06068.8 ABX13119.1 - 0.00011 21.0 0.0 0.23 10.1 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus Rad17 PF03215.10 ABX13119.1 - 0.00055 18.7 0.0 0.56 8.8 0.0 2.4 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 ABX13119.1 - 0.00063 19.3 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 ABX13119.1 - 0.00088 18.5 0.8 0.74 9.0 0.0 3.4 3 0 0 3 3 3 1 PhoH-like protein ATP-synt_ab PF00006.20 ABX13119.1 - 0.0014 18.1 0.0 1.4 8.3 0.0 2.9 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 ABX13119.1 - 0.0018 17.7 0.1 0.73 9.2 0.0 3.5 3 1 0 3 3 3 1 Sigma-54 interaction domain KAP_NTPase PF07693.9 ABX13119.1 - 0.0024 16.9 0.1 2.6 6.9 0.0 3.4 2 2 1 3 3 3 1 KAP family P-loop domain SKI PF01202.17 ABX13119.1 - 0.0041 16.9 0.0 0.97 9.2 0.0 3.0 3 0 0 3 3 3 1 Shikimate kinase DUF2075 PF09848.4 ABX13119.1 - 0.0046 15.9 0.0 1.9 7.3 0.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 ABX13119.1 - 0.0069 15.9 0.0 1.2 8.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 ABX13119.1 - 0.011 15.2 0.0 4.3 6.9 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 ABX13119.1 - 0.017 14.5 0.4 13 5.1 0.0 3.7 2 2 2 4 4 4 0 AAA-like domain UPF0079 PF02367.12 ABX13119.1 - 0.021 14.4 0.1 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 ABX13119.1 - 0.027 14.3 0.0 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SRPRB PF09439.5 ABX13119.1 - 0.028 13.6 0.0 15 4.7 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DAP3 PF10236.4 ABX13119.1 - 0.036 12.9 0.0 2.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_21 PF13304.1 ABX13119.1 - 0.051 13.5 0.8 15 5.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 ABX13119.1 - 0.061 12.1 0.0 3.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 ABX13119.1 - 0.1 11.4 0.3 3.2 6.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF2312 PF10073.4 ABX13119.1 - 0.5 9.7 2.9 1.5 8.2 0.0 2.9 4 0 0 4 4 2 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF1456 PF07308.8 ABX13120.1 - 0.0004 20.3 1.3 0.0012 18.8 0.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1456) DUF4110 PF13422.1 ABX13120.1 - 0.25 11.1 1.7 0.67 9.8 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4110) UbiA PF01040.13 ABX13121.1 - 4.1e-29 101.5 20.1 5.2e-29 101.2 13.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Copper-bind PF00127.15 ABX13122.1 - 1.9e-16 60.1 1.1 2.2e-09 37.4 0.2 3.1 2 2 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 ABX13122.1 - 1.1e-13 50.9 0.0 2e-06 27.6 0.0 2.7 1 1 1 2 2 2 2 Cupredoxin-like domain Bax1-I PF01027.15 ABX13122.1 - 0.87 9.1 21.1 1.2 8.7 14.7 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Prok-JAB PF14464.1 ABX13123.1 - 5.1e-19 67.7 0.0 6e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.16 ABX13123.1 - 7.1e-09 35.4 0.0 9.3e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Toxin-JAB1 PF15659.1 ABX13123.1 - 0.00019 21.3 0.8 0.00023 21.1 0.6 1.2 1 0 0 1 1 1 1 JAB-like toxin 1 RadC PF04002.10 ABX13123.1 - 0.11 12.2 0.2 0.17 11.5 0.1 1.5 1 1 0 1 1 1 0 RadC-like JAB domain Cyclophil_like PF04126.8 ABX13124.1 - 1.7e-44 150.2 0.0 1.9e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin-like DUF3830 PF12903.2 ABX13124.1 - 0.073 12.4 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) DUF2024 PF09630.5 ABX13125.1 - 1.2e-39 133.9 1.1 1.3e-39 133.7 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) Cytochrom_NNT PF03264.9 ABX13125.1 - 0.057 12.8 0.2 0.06 12.7 0.2 1.1 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Haem_bd PF14376.1 ABX13125.1 - 0.07 12.8 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Haem-binding domain H_PPase PF03030.11 ABX13127.1 - 2.2e-225 750.0 51.7 2.6e-225 749.8 35.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF45 PF01863.12 ABX13128.1 - 0.002 17.9 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 ABX13128.1 - 0.0041 16.7 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Peptidase_M76 PF09768.4 ABX13128.1 - 0.095 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase M76 family DUF359 PF04019.7 ABX13129.1 - 3.9e-36 123.0 0.4 5.1e-36 122.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF359) DRTGG PF07085.7 ABX13129.1 - 0.029 13.9 0.0 0.081 12.5 0.0 1.7 2 0 0 2 2 2 0 DRTGG domain ParA PF10609.4 ABX13130.1 - 4.2e-36 122.6 0.2 9.7e-36 121.5 0.2 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 ABX13130.1 - 5.2e-20 71.6 0.1 7.9e-20 71.0 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF59 PF01883.14 ABX13130.1 - 9.6e-18 63.9 0.6 3.4e-17 62.1 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function DUF59 AAA_31 PF13614.1 ABX13130.1 - 2.5e-11 43.7 0.1 1e-10 41.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 ABX13130.1 - 6e-08 32.0 0.0 1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 ABX13130.1 - 8.7e-07 28.7 0.5 0.013 15.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain Fer4_NifH PF00142.13 ABX13130.1 - 6.2e-06 25.5 0.1 0.0016 17.6 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 ABX13130.1 - 0.00029 19.9 1.0 0.00029 19.9 0.7 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.6 ABX13130.1 - 0.0041 16.2 0.0 0.0079 15.2 0.0 1.4 1 0 0 1 1 1 1 VirC1 protein ArgK PF03308.11 ABX13130.1 - 0.0069 15.1 0.2 0.011 14.5 0.1 1.3 1 0 0 1 1 1 1 ArgK protein SRP54 PF00448.17 ABX13130.1 - 0.031 13.7 0.7 0.3 10.5 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain YhjQ PF06564.7 ABX13130.1 - 0.045 13.1 0.4 0.084 12.2 0.3 1.5 1 1 0 1 1 1 0 YhjQ protein APS_kinase PF01583.15 ABX13130.1 - 0.076 12.6 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.1 ABX13130.1 - 0.11 11.8 0.5 0.22 10.9 0.4 1.4 1 0 0 1 1 1 0 AAA domain SHS2_Rpb7-N PF03876.12 ABX13131.1 - 5.3e-17 61.7 0.0 1.4e-16 60.3 0.0 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 ABX13131.1 - 2.8e-14 52.9 0.0 4.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.1 ABX13131.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 S1 domain BPL_C PF02237.12 ABX13131.1 - 0.032 13.9 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Spt4 PF06093.8 ABX13132.1 - 6.2e-13 48.4 0.6 7.8e-13 48.1 0.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RecR PF02132.10 ABX13132.1 - 0.019 14.4 0.4 0.024 14.0 0.3 1.2 1 0 0 1 1 1 0 RecR protein TF_Zn_Ribbon PF08271.7 ABX13132.1 - 0.023 13.9 0.6 0.066 12.5 0.0 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding Laminin_EGF PF00053.19 ABX13132.1 - 0.028 14.3 0.5 0.038 13.9 0.3 1.2 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) RPA_interact_C PF14768.1 ABX13132.1 - 0.12 12.8 1.1 1.2 9.5 0.0 2.1 2 0 0 2 2 2 0 Replication protein A interacting C-terminal zf-C3HC4_2 PF13923.1 ABX13132.1 - 0.26 11.3 2.2 0.36 10.8 1.5 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_POL_M_15KD PF02150.11 ABX13132.1 - 0.27 10.9 0.2 0.27 10.9 0.2 2.0 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C3HC4_3 PF13920.1 ABX13132.1 - 0.29 10.8 3.2 0.42 10.3 2.2 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ABX13132.1 - 0.32 10.7 2.8 0.46 10.2 1.9 1.2 1 0 0 1 1 1 0 zinc-RING finger domain Prim_Zn_Ribbon PF08273.7 ABX13132.1 - 1.5 8.9 4.0 2 8.5 0.2 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase QRPTase_C PF01729.14 ABX13133.1 - 8.4e-55 184.8 1.1 8.4e-55 184.8 0.7 1.4 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 ABX13133.1 - 6.6e-25 86.7 0.0 1.1e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.14 ABX13133.1 - 0.0032 16.5 0.1 0.0059 15.7 0.0 1.4 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TPR_11 PF13414.1 ABX13134.1 - 1.5e-15 56.5 0.3 7.9e-12 44.6 0.0 2.1 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 ABX13134.1 - 7.5e-15 53.8 2.4 1.4e-05 24.4 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ABX13134.1 - 1.6e-14 52.5 0.5 0.00022 20.9 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 ABX13134.1 - 2.9e-14 52.9 6.8 8.8e-10 38.5 0.5 1.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ABX13134.1 - 4e-11 43.0 0.7 3e-08 33.8 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ABX13134.1 - 1.1e-09 38.7 0.0 2.6e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ABX13134.1 - 2.6e-08 33.6 1.0 1.5e-06 28.0 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ABX13134.1 - 3.8e-07 29.8 3.4 0.0028 17.5 0.1 3.0 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 ABX13134.1 - 1.6e-06 27.8 2.1 0.11 12.7 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ABX13134.1 - 3.6e-06 26.3 3.5 0.033 13.9 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ABX13134.1 - 4.3e-06 26.8 0.0 0.06 14.0 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ABX13134.1 - 2.7e-05 23.6 0.2 0.065 13.0 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ABX13134.1 - 8.4e-05 22.7 0.1 0.5 10.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ABX13134.1 - 0.00026 20.7 0.0 0.16 11.8 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 ABX13134.1 - 0.00036 20.2 6.7 0.002 17.9 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Clathrin PF00637.15 ABX13134.1 - 0.0066 16.0 0.5 0.075 12.6 0.4 2.1 1 1 0 1 1 1 1 Region in Clathrin and VPS DUF1489 PF07370.6 ABX13134.1 - 0.03 13.8 0.0 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1489) P4Ha_N PF08336.6 ABX13134.1 - 0.052 13.3 0.1 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Cas_Cas02710 PF09670.5 ABX13134.1 - 0.091 11.3 0.3 0.11 11.0 0.2 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) NadA PF02445.11 ABX13135.1 - 1.5e-116 388.3 4.1 1.7e-116 388.2 2.9 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein DUF108 PF01958.13 ABX13136.1 - 9.3e-35 118.7 0.8 2.2e-34 117.5 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.11 ABX13136.1 - 1.3e-15 57.7 0.0 2.7e-15 56.8 0.0 1.5 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 ABX13136.1 - 4e-05 23.5 0.0 8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 ABX13136.1 - 0.0004 20.6 0.0 0.0007 19.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 ABX13136.1 - 0.0011 19.2 0.2 0.005 17.2 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 ABX13136.1 - 0.0067 16.9 0.1 0.021 15.3 0.0 1.8 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.13 ABX13136.1 - 0.0069 16.0 0.0 0.04 13.5 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 ABX13136.1 - 0.0073 16.1 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NurA PF09376.5 ABX13138.1 - 8.8e-20 71.2 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 NurA domain OpuAC PF04069.7 ABX13138.1 - 0.044 13.1 0.0 0.13 11.6 0.0 1.6 1 1 1 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system DUF87 PF01935.12 ABX13139.1 - 9.3e-37 127.0 3.4 2.4e-36 125.7 2.4 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_10 PF12846.2 ABX13139.1 - 1e-15 57.9 5.0 3e-11 43.3 0.9 2.2 1 1 0 2 2 2 2 AAA-like domain TrwB_AAD_bind PF10412.4 ABX13139.1 - 0.0031 16.1 0.1 0.0078 14.8 0.0 1.7 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 ABX13139.1 - 0.015 15.6 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Metallophos_2 PF12850.2 ABX13140.1 - 2e-11 43.9 0.1 3.1e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ABX13140.1 - 9.2e-10 38.2 1.3 1.7e-09 37.3 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF211 PF02680.9 ABX13140.1 - 0.12 12.2 1.0 8.6 6.2 0.1 3.2 2 1 1 3 3 3 0 Uncharacterized ArCR, COG1888 AAA_23 PF13476.1 ABX13141.1 - 1.1e-14 55.2 88.4 2.1e-07 31.4 50.3 4.6 1 1 1 2 2 1 1 AAA domain SMC_N PF02463.14 ABX13141.1 - 8e-14 51.3 31.9 3.5e-09 36.2 0.5 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ABX13141.1 - 1.2e-10 41.7 28.3 8.4e-07 29.2 7.6 3.3 2 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 ABX13141.1 - 3.9e-10 39.3 65.9 0.00069 18.7 18.3 3.1 1 1 1 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 ABX13141.1 - 4.7e-09 35.6 0.1 9.9e-09 34.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 ABX13141.1 - 2.4e-08 33.7 0.0 5.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 ABX13141.1 - 2.3e-06 26.4 73.6 0.00022 19.8 20.6 4.1 1 1 3 4 4 4 4 AAA domain DUF258 PF03193.11 ABX13141.1 - 0.0012 18.0 0.1 0.0064 15.7 0.1 2.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ABX13141.1 - 0.0074 16.5 0.1 0.0074 16.5 0.1 5.4 2 1 1 3 3 2 1 ABC transporter MukB PF04310.7 ABX13141.1 - 0.029 13.6 0.1 0.084 12.1 0.1 1.8 1 0 0 1 1 1 0 MukB N-terminal Spc7 PF08317.6 ABX13141.1 - 0.052 12.2 68.0 0.0056 15.3 10.1 4.3 1 1 3 4 4 4 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 ABX13141.1 - 0.1 11.7 19.4 0.088 11.9 0.7 3.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein MMR_HSR1 PF01926.18 ABX13141.1 - 0.18 11.7 4.0 0.34 10.8 0.4 3.2 1 1 2 3 3 3 0 50S ribosome-binding GTPase WEMBL PF05701.6 ABX13141.1 - 0.27 9.6 53.3 0.074 11.5 19.1 2.9 1 1 0 2 2 2 0 Weak chloroplast movement under blue light APG6 PF04111.7 ABX13141.1 - 0.88 8.5 60.2 0.077 12.0 3.7 3.5 1 1 2 3 3 3 0 Autophagy protein Apg6 AAA_16 PF13191.1 ABX13141.1 - 1.2 9.0 5.4 7.4 6.5 3.7 2.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.1 ABX13141.1 - 1.3 6.6 49.0 0.083 10.5 0.1 4.1 2 1 2 5 5 5 0 AAA domain AT_hook PF02178.14 ABX13142.1 - 0.23 11.2 4.7 0.53 10.1 3.3 1.6 1 0 0 1 1 1 0 AT hook motif HATPase_c PF02518.21 ABX13143.1 - 6.6e-18 64.4 0.1 1.3e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ABX13143.1 - 1.1e-09 38.1 0.2 2.9e-09 36.7 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 ABX13143.1 - 1.4e-08 34.3 3.0 1.5e-08 34.2 0.5 2.3 2 1 0 2 2 2 1 GHKL domain Cache_3 PF14827.1 ABX13143.1 - 8.6e-06 25.6 0.0 0.053 13.4 0.0 2.5 2 0 0 2 2 2 2 Sensory domain of two-component sensor kinase DUF2935 PF11155.3 ABX13143.1 - 0.089 12.8 6.5 1.5 8.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) DUF948 PF06103.6 ABX13143.1 - 3.4 7.6 8.7 2.1 8.2 1.8 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Response_reg PF00072.19 ABX13144.1 - 3.8e-15 55.8 0.0 4.2e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Trypan_PARP PF05887.6 ABX13146.1 - 1.7e-10 40.8 41.9 3.5e-10 39.8 29.0 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Kazal_1 PF00050.16 ABX13146.1 - 3.3e-09 36.6 0.4 9.7e-09 35.1 0.3 1.8 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 ABX13146.1 - 8.8e-07 28.7 0.9 8.8e-07 28.7 0.7 1.6 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Copper-bind PF00127.15 ABX13146.1 - 5.4e-06 26.5 0.5 1.3e-05 25.3 0.3 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 ABX13146.1 - 0.0046 16.8 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 Cupredoxin-like domain HEAT_2 PF13646.1 ABX13147.1 - 1.1e-26 92.9 0.1 7.7e-19 67.7 0.1 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 ABX13147.1 - 5.7e-15 53.9 0.1 0.0027 17.6 0.0 4.2 4 0 0 4 4 4 4 HEAT repeat HEAT_PBS PF03130.11 ABX13147.1 - 2.4e-12 46.0 0.0 0.0003 20.9 0.1 3.6 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 ABX13147.1 - 2.6e-12 46.8 0.0 0.022 15.2 0.0 3.9 4 0 0 4 4 4 3 HEAT-like repeat Arm PF00514.18 ABX13147.1 - 6.5e-05 22.6 0.0 0.6 10.0 0.0 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 ABX13147.1 - 0.0006 18.2 0.1 0.0024 16.2 0.0 1.8 1 1 1 2 2 2 2 Adaptin N terminal region DUF2019 PF09450.5 ABX13147.1 - 0.13 12.0 0.0 6.5 6.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2019) Redoxin PF08534.5 ABX13148.1 - 4.1e-08 32.8 0.1 2.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.16 ABX13148.1 - 9.4e-08 31.7 0.2 1.7e-06 27.7 0.1 2.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 ABX13148.1 - 3.7e-05 23.8 0.3 0.00074 19.6 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ABX13148.1 - 0.00039 20.4 0.1 0.098 12.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_4 PF13462.1 ABX13148.1 - 0.032 14.2 0.0 0.098 12.6 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin GSHPx PF00255.14 ABX13148.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase Ribosomal_L15e PF00827.12 ABX13150.1 - 5.6e-46 156.4 3.5 6.9e-46 156.1 2.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 MadM PF03818.8 ABX13153.1 - 0.074 12.6 1.3 0.1 12.1 0.2 1.7 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit 2-Hacid_dh_C PF02826.14 ABX13154.1 - 2.9e-60 202.4 0.2 5.5e-60 201.5 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ABX13154.1 - 2.2e-29 101.5 0.4 2.6e-29 101.3 0.3 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ABX13154.1 - 0.00095 19.0 0.9 0.0026 17.6 0.0 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3436 PF11918.3 ABX13154.1 - 0.038 14.2 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3436) Cu-oxidase_3 PF07732.10 ABX13155.1 - 2.2e-08 33.8 1.4 3.5e-07 29.9 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ABX13155.1 - 0.0012 18.3 1.4 0.27 10.7 0.2 2.6 2 1 0 2 2 2 2 Multicopper oxidase Lyase_1 PF00206.15 ABX13156.1 - 1.1e-88 297.4 0.8 1.5e-88 296.9 0.6 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 ABX13156.1 - 5.2e-13 48.8 0.0 1.3e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Radical_SAM PF04055.16 ABX13157.1 - 2.1e-20 73.5 0.1 3.3e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 ABX13157.1 - 9.5e-17 60.6 0.9 1.8e-16 59.7 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 ABX13157.1 - 0.0003 20.5 0.1 0.00092 18.9 0.0 1.9 2 0 0 2 2 2 1 TRAM domain Tubulin PF00091.20 ABX13158.1 - 8.5e-15 55.1 0.1 1.8e-13 50.8 0.0 2.1 1 1 1 2 2 2 1 Tubulin/FtsZ family, GTPase domain DUF4147 PF13660.1 ABX13158.1 - 0.082 11.9 0.1 9.5 5.2 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4147) Ribosomal_L31e PF01198.14 ABX13159.1 - 1.1e-23 82.6 0.3 2.5e-23 81.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L31e Mitofilin PF09731.4 ABX13159.1 - 1.3 7.6 21.5 1.3 7.5 14.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Asp-B-Hydro_N PF05279.6 ABX13159.1 - 3.6 7.3 30.0 4.3 7.1 20.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_L39 PF00832.15 ABX13160.1 - 1.2e-19 69.4 6.7 1.4e-19 69.2 4.6 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein REV PF00424.13 ABX13160.1 - 0.13 12.1 1.7 0.14 12.1 1.2 1.1 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) NUDIX PF00293.23 ABX13161.1 - 5.8e-12 45.4 0.0 7.7e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MTHFR PF02219.12 ABX13162.1 - 1.1e-05 24.6 0.0 2e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase Rsbr_N PF08678.5 ABX13162.1 - 0.059 13.2 0.6 1 9.2 0.0 2.5 3 0 0 3 3 3 0 Rsbr N terminal DUF2935 PF11155.3 ABX13162.1 - 0.28 11.2 1.7 1.1 9.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Pterin_bind PF00809.17 ABX13163.1 - 2e-20 73.1 0.0 3.1e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme Met_synt_B12 PF02965.12 ABX13163.1 - 3.2e-19 68.9 0.0 5.8e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding PF02310.14 ABX13163.1 - 7.7e-18 64.5 0.0 1.8e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.12 ABX13163.1 - 4.5e-14 52.2 0.0 1.4e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 B12 binding domain CdhD PF03599.11 ABX13163.1 - 0.0043 15.6 0.0 0.0081 14.6 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit S-methyl_trans PF02574.11 ABX13164.1 - 5.1e-69 232.9 0.0 5.7e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase MFS_1 PF07690.11 ABX13165.1 - 2.6e-26 92.2 46.1 4.6e-25 88.0 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4094 PF13334.1 ABX13165.1 - 0.041 14.2 1.1 0.058 13.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF4508 PF14969.1 ABX13166.1 - 0.049 13.6 0.5 1.1 9.3 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4508) CBS PF00571.23 ABX13167.1 - 4.5e-39 131.9 0.1 1e-10 41.1 0.0 4.1 4 0 0 4 4 4 4 CBS domain DUF2497 PF10691.4 ABX13167.1 - 0.0067 16.3 1.7 1.9 8.5 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2497) 5-nucleotidase PF06189.7 ABX13167.1 - 0.036 12.8 0.0 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 5'-nucleotidase Usp PF00582.21 ABX13168.1 - 4.8e-24 85.1 0.0 5.9e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Caerin_1 PF07440.7 ABX13168.1 - 0.11 12.4 0.4 17 5.3 0.2 2.4 2 0 0 2 2 2 0 Caerin 1 protein Copper-bind PF00127.15 ABX13169.1 - 0.00034 20.8 0.3 0.0015 18.7 0.0 2.2 2 1 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 ABX13169.1 - 0.0007 19.4 0.0 0.0029 17.4 0.0 2.1 2 1 0 2 2 2 1 Cupredoxin-like domain PKD PF00801.15 ABX13169.1 - 0.031 14.0 1.8 0.74 9.5 0.5 3.1 3 1 0 3 3 3 0 PKD domain Usp PF00582.21 ABX13170.1 - 3.3e-32 111.6 0.0 3.7e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family GARS_N PF02844.10 ABX13170.1 - 0.039 14.4 0.1 0.1 13.0 0.0 1.7 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain AP_endonuc_2 PF01261.19 ABX13170.1 - 0.058 12.6 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Rhodanese PF00581.15 ABX13171.1 - 3.4e-23 82.1 0.0 5.4e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain YjeF_N PF03853.10 ABX13171.1 - 0.11 12.1 0.0 0.65 9.5 0.0 2.0 2 0 0 2 2 2 0 YjeF-related protein N-terminus HTH_24 PF13412.1 ABX13172.1 - 8.6e-12 44.2 0.0 0.00011 21.4 0.0 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding TrmB PF01978.14 ABX13172.1 - 4.3e-07 29.5 0.3 0.004 16.8 0.1 2.2 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.11 ABX13172.1 - 9.4e-07 28.9 0.3 0.021 14.9 0.0 2.2 2 0 0 2 2 2 2 Penicillinase repressor MarR_2 PF12802.2 ABX13172.1 - 3.4e-06 26.6 0.0 0.0093 15.6 0.0 2.2 2 0 0 2 2 2 2 MarR family MarR PF01047.17 ABX13172.1 - 9.9e-06 25.1 0.0 0.036 13.7 0.0 2.2 2 0 0 2 2 2 2 MarR family HTH_5 PF01022.15 ABX13172.1 - 2.1e-05 24.1 0.0 0.0096 15.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family HTH_27 PF13463.1 ABX13172.1 - 0.00065 19.9 0.0 0.083 13.2 0.0 2.3 2 0 0 2 2 2 1 Winged helix DNA-binding domain Fe_dep_repress PF01325.14 ABX13172.1 - 0.015 15.2 0.1 0.89 9.5 0.0 2.5 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain FeoC PF09012.5 ABX13172.1 - 0.015 14.9 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_20 PF12840.2 ABX13172.1 - 0.015 15.0 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2250 PF10007.4 ABX13172.1 - 0.066 13.1 2.9 2.4 8.1 0.4 2.7 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) DUF4364 PF14277.1 ABX13172.1 - 0.072 12.7 1.8 1.3 8.5 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4364) DrsE PF02635.10 ABX13173.1 - 4.7e-07 29.8 0.1 6.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE_2 PF13686.1 ABX13173.1 - 0.013 15.2 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family BTP PF05232.7 ABX13174.1 - 0.49 10.1 1.9 1.6 8.4 0.8 2.0 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family HTH_24 PF13412.1 ABX13177.1 - 1.7e-13 49.7 2.8 4.2e-06 26.0 0.1 2.8 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 ABX13177.1 - 5.3e-09 35.6 0.0 6.7e-05 22.4 0.0 2.6 2 1 0 2 2 2 2 MarR family HTH_34 PF13601.1 ABX13177.1 - 1e-08 35.0 1.2 0.00011 22.0 0.1 2.3 2 1 0 2 2 2 2 Winged helix DNA-binding domain HTH_20 PF12840.2 ABX13177.1 - 5.9e-08 32.3 0.0 0.0034 17.1 0.0 2.1 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_5 PF01022.15 ABX13177.1 - 6.1e-08 32.2 0.3 6.3e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR PF01047.17 ABX13177.1 - 2.9e-07 30.0 0.8 0.0087 15.7 0.0 2.8 3 0 0 3 3 3 2 MarR family TrmB PF01978.14 ABX13177.1 - 4.3e-05 23.1 1.3 0.19 11.4 0.1 2.4 2 1 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.1 ABX13177.1 - 0.00012 22.2 0.1 0.072 13.4 0.0 2.3 2 0 0 2 2 2 2 Winged helix DNA-binding domain HTH_45 PF14947.1 ABX13177.1 - 0.0019 17.9 2.4 0.69 9.7 0.0 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix Pox_H7 PF04787.7 ABX13177.1 - 0.012 15.4 0.5 0.016 14.9 0.3 1.4 1 0 0 1 1 1 0 Late protein H7 HTH_IclR PF09339.5 ABX13177.1 - 0.032 13.8 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain Fe_dep_repress PF01325.14 ABX13177.1 - 0.09 12.7 0.2 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain MerR_1 PF13411.1 ABX13177.1 - 0.19 11.5 1.9 0.21 11.3 0.1 2.0 2 0 0 2 2 2 0 MerR HTH family regulatory protein TINF2_N PF14973.1 ABX13178.1 - 0.032 14.3 0.1 0.055 13.6 0.1 1.5 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus BPD_transp_1 PF00528.17 ABX13179.1 - 1.3e-22 80.2 15.0 2.1e-22 79.5 10.4 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF3188 PF11384.3 ABX13179.1 - 2.4 7.8 7.1 0.51 9.9 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) ABC_tran PF00005.22 ABX13180.1 - 1.9e-31 109.1 0.0 3.4e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ABX13180.1 - 4.5e-12 46.5 0.0 1.1e-05 25.5 0.0 2.2 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ABX13180.1 - 0.00027 21.0 0.1 0.00055 19.9 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.1 ABX13180.1 - 0.00066 18.8 0.0 0.045 12.7 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 ABX13180.1 - 0.00074 19.7 0.4 0.011 15.9 0.2 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ABX13180.1 - 0.0038 17.3 0.1 0.015 15.4 0.0 2.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ABX13180.1 - 0.0044 17.8 0.5 0.017 15.9 0.2 1.9 1 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ABX13180.1 - 0.0045 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 ABX13180.1 - 0.0074 15.4 0.0 0.011 14.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 ABX13180.1 - 0.016 14.4 0.2 2.8 7.0 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 ABX13180.1 - 0.018 15.5 0.0 0.057 13.9 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein AAA_5 PF07728.9 ABX13180.1 - 0.024 14.3 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 ABX13180.1 - 0.025 14.2 0.0 0.057 13.1 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 ABX13180.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 ABX13180.1 - 0.031 13.9 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 ABX13180.1 - 0.045 13.1 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 ABX13180.1 - 0.06 12.0 0.1 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 ABX13180.1 - 0.068 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 ABX13180.1 - 0.08 12.5 0.0 0.74 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ABX13180.1 - 0.08 13.1 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA helicase ABC_ATPase PF09818.4 ABX13180.1 - 0.12 10.9 0.2 0.21 10.1 0.1 1.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.1 ABX13180.1 - 0.13 12.6 0.2 0.25 11.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ABX13180.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain NMT1_2 PF13379.1 ABX13181.1 - 3.2e-29 102.0 0.0 4.4e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.6 ABX13181.1 - 7.1e-14 51.9 0.0 9.6e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.2 ABX13181.1 - 1.7e-09 37.4 0.0 5.3e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 ABX13181.1 - 6.4e-05 22.3 0.0 0.049 12.8 0.0 2.9 2 1 1 3 3 3 2 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_7 PF03480.8 ABX13181.1 - 0.1 11.6 0.0 1.4 7.9 0.0 2.5 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Pep_deformylase PF01327.16 ABX13181.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase Arginosuc_synth PF00764.14 ABX13182.1 - 2e-158 527.5 0.2 2.3e-158 527.3 0.1 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 ABX13182.1 - 5.6e-07 29.3 0.0 8.3e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 ABX13182.1 - 0.00019 20.8 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Flagellin_IN PF07196.8 ABX13182.1 - 0.084 12.8 0.8 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Flagellin hook IN motif zinc_ribbon_5 PF13719.1 ABX13183.1 - 2.1e-06 27.1 0.7 0.023 14.2 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ABX13183.1 - 4.7e-06 26.1 0.7 0.045 13.4 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 ABX13183.1 - 0.00046 19.4 1.5 0.00071 18.8 1.0 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 ABX13183.1 - 0.0005 19.1 1.0 0.56 9.4 0.0 2.2 2 0 0 2 2 2 2 zinc-ribbon domain UPF0547 PF10571.4 ABX13183.1 - 0.0011 18.6 3.3 0.0081 15.8 2.3 2.0 1 1 0 1 1 1 1 Uncharacterised protein family UPF0547 DNA_RNApol_7kD PF03604.8 ABX13183.1 - 0.0024 17.2 2.3 0.34 10.4 1.1 2.8 1 1 2 3 3 3 2 DNA directed RNA polymerase, 7 kDa subunit zf-HYPF PF07503.7 ABX13183.1 - 0.0041 16.4 1.6 0.17 11.3 0.0 2.1 2 0 0 2 2 2 1 HypF finger DZR PF12773.2 ABX13183.1 - 0.007 16.1 0.5 0.011 15.4 0.3 1.4 1 1 0 1 1 1 1 Double zinc ribbon zf-C4_Topoisom PF01396.14 ABX13183.1 - 0.0081 15.6 1.2 1.6 8.3 0.0 2.2 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger Prok-RING_1 PF14446.1 ABX13183.1 - 0.0092 15.7 4.1 0.027 14.1 2.8 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 Zn_Tnp_IS1 PF03811.8 ABX13183.1 - 0.0099 15.3 0.5 1.8 8.1 0.0 2.3 2 0 0 2 2 2 1 InsA N-terminal domain zf-IS66 PF13005.2 ABX13183.1 - 0.011 15.7 0.4 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-TFIIB PF13453.1 ABX13183.1 - 0.011 14.9 1.9 0.14 11.3 2.2 1.9 1 1 1 2 2 2 0 Transcription factor zinc-finger A2L_zn_ribbon PF08792.5 ABX13183.1 - 0.011 15.1 0.9 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain HypA PF01155.14 ABX13183.1 - 0.011 15.3 0.2 0.012 15.2 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DNA_ligase_ZBD PF03119.11 ABX13183.1 - 0.016 14.9 4.0 0.34 10.6 0.2 2.4 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain RNA_POL_M_15KD PF02150.11 ABX13183.1 - 0.018 14.6 0.3 0.031 13.9 0.2 1.4 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit OrfB_Zn_ribbon PF07282.6 ABX13183.1 - 0.021 14.4 0.1 0.03 13.9 0.1 1.3 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.7 ABX13183.1 - 0.024 14.4 0.9 0.077 12.7 0.6 1.7 1 1 0 1 1 1 0 zinc-ribbons Lar_restr_allev PF14354.1 ABX13183.1 - 0.026 14.8 2.5 0.049 13.9 1.8 1.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 ABX13183.1 - 0.036 13.5 0.9 0.26 10.8 0.7 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_3 PF14369.1 ABX13183.1 - 0.038 14.0 4.4 0.11 12.4 3.0 1.7 1 1 0 1 1 1 0 zinc-finger DUF2387 PF09526.5 ABX13183.1 - 0.045 13.6 0.4 0.058 13.3 0.3 1.2 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) DUF164 PF02591.10 ABX13183.1 - 0.052 13.3 1.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Putative zinc ribbon domain Ogr_Delta PF04606.7 ABX13183.1 - 0.071 12.7 0.6 6.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DUF329 PF03884.9 ABX13183.1 - 0.074 12.6 2.1 2.3 7.8 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF329) PAAR_motif PF05488.8 ABX13183.1 - 0.082 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 PAAR motif ADK_lid PF05191.9 ABX13183.1 - 0.1 12.2 0.8 2.3 7.9 0.1 2.3 2 1 0 2 2 2 0 Adenylate kinase, active site lid CpXC PF14353.1 ABX13183.1 - 0.1 12.5 0.2 3.9 7.4 0.0 2.1 2 0 0 2 2 2 0 CpXC protein PhnA_Zn_Ribbon PF08274.7 ABX13183.1 - 0.1 12.3 3.2 1.1 9.0 2.4 2.1 1 1 1 2 2 2 0 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.5 ABX13183.1 - 0.14 12.1 3.9 1.5 8.8 0.2 2.0 1 1 0 2 2 2 0 Zinc ribbon domain zf-CSL PF05207.8 ABX13183.1 - 0.19 11.2 2.1 0.38 10.3 0.1 2.0 1 1 1 2 2 2 0 CSL zinc finger TerY-C PF15616.1 ABX13183.1 - 0.19 11.6 1.3 1.3 8.9 0.9 1.9 1 1 0 1 1 1 0 TerY-C metal binding domain Rubredoxin PF00301.15 ABX13183.1 - 2 8.3 7.5 3.8 7.4 0.4 2.5 1 1 2 3 3 2 0 Rubredoxin DUF3797 PF12677.2 ABX13183.1 - 2.9 7.6 4.3 2 8.0 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) RimK PF08443.6 ABX13184.1 - 7.7e-42 142.9 0.0 9.8e-42 142.5 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 ABX13184.1 - 1.8e-16 60.4 0.0 3.1e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GSH-S_ATP PF02955.11 ABX13184.1 - 2e-10 40.0 0.0 2.7e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_Ter PF15632.1 ABX13184.1 - 3.3e-09 35.9 0.0 5.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 ABX13184.1 - 1.2e-08 35.0 0.0 3e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 ABX13184.1 - 1e-06 28.1 0.0 7.4e-06 25.4 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ABX13184.1 - 0.0001 21.7 0.0 0.089 12.1 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 ABX13184.1 - 0.00056 19.2 0.0 0.0013 18.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 ABX13184.1 - 0.0006 19.4 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_YheCD PF14398.1 ABX13184.1 - 0.001 17.9 0.0 0.057 12.2 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_5 PF13549.1 ABX13184.1 - 0.0024 17.1 0.0 0.0058 15.8 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.1 ABX13184.1 - 0.013 14.6 0.0 0.057 12.4 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Synapsin_C PF02750.9 ABX13184.1 - 0.05 12.6 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Synapsin, ATP binding domain Semialdhyde_dh PF01118.19 ABX13185.1 - 8.6e-36 122.9 0.0 1.4e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.13 ABX13185.1 - 5.9e-17 62.1 0.0 9.4e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain GFO_IDH_MocA PF01408.17 ABX13185.1 - 6.8e-05 23.3 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 ABX13185.1 - 0.00016 20.7 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 ABX13185.1 - 0.00026 20.9 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 ABX13185.1 - 0.0098 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding AA_kinase PF00696.23 ABX13186.1 - 3.6e-35 121.6 3.1 4.1e-35 121.4 2.1 1.0 1 0 0 1 1 1 1 Amino acid kinase family Aminotran_3 PF00202.16 ABX13187.1 - 6.3e-105 350.7 0.1 7.4e-105 350.5 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 ABX13187.1 - 4.1e-05 22.7 0.0 0.0001 21.3 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II DUF2931 PF11153.3 ABX13187.1 - 0.024 13.9 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) Aminotran_5 PF00266.14 ABX13187.1 - 0.032 12.9 0.0 0.048 12.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V HTH_AsnC-type PF13404.1 ABX13188.1 - 2.5e-12 46.1 0.0 4.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.16 ABX13188.1 - 3e-12 46.0 0.3 4.1e-12 45.6 0.2 1.2 1 0 0 1 1 1 1 AsnC family HTH_24 PF13412.1 ABX13188.1 - 1.5e-10 40.3 0.2 2.4e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Mga PF05043.8 ABX13188.1 - 0.0031 17.7 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 Mga helix-turn-helix domain HTH_11 PF08279.7 ABX13188.1 - 0.0031 17.1 0.4 0.0069 16.0 0.0 1.7 2 0 0 2 2 2 1 HTH domain FeoC PF09012.5 ABX13188.1 - 0.0048 16.5 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 FeoC like transcriptional regulator ACT_4 PF13291.1 ABX13188.1 - 0.0055 17.0 0.4 1.2 9.4 0.1 2.2 2 0 0 2 2 2 1 ACT domain HTH_Tnp_ISL3 PF13542.1 ABX13188.1 - 0.0085 15.2 0.0 0.02 14.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.11 ABX13188.1 - 0.013 14.7 0.0 0.037 13.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 TrmB PF01978.14 ABX13188.1 - 0.028 14.1 0.7 0.47 10.2 0.1 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB DDRGK PF09756.4 ABX13188.1 - 0.032 13.6 0.6 0.085 12.2 0.1 1.8 2 0 0 2 2 2 0 DDRGK domain NapD PF03927.8 ABX13188.1 - 0.036 13.8 0.7 0.059 13.2 0.5 1.4 1 0 0 1 1 1 0 NapD protein MarR PF01047.17 ABX13188.1 - 0.039 13.6 0.4 0.09 12.4 0.0 1.8 2 0 0 2 2 2 0 MarR family MarR_2 PF12802.2 ABX13188.1 - 0.043 13.4 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_9 PF08221.6 ABX13188.1 - 0.074 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_34 PF13601.1 ABX13188.1 - 0.075 13.0 0.1 0.24 11.4 0.0 1.9 1 1 0 2 2 2 0 Winged helix DNA-binding domain HTH_5 PF01022.15 ABX13188.1 - 0.11 12.2 0.0 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HMGL-like PF00682.14 ABX13189.1 - 7.3e-63 212.3 0.0 1.1e-62 211.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like zinc_ribbon_4 PF13717.1 ABX13190.1 - 2.4e-06 27.1 3.6 0.0014 18.2 0.9 2.1 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.1 ABX13190.1 - 5.1e-05 22.7 0.8 0.00098 18.6 0.6 2.1 1 1 0 1 1 1 1 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 ABX13190.1 - 0.00026 20.6 6.4 0.0045 16.7 2.2 2.0 1 1 1 2 2 2 2 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.1 ABX13190.1 - 0.00092 18.3 0.3 0.022 13.9 0.0 2.1 2 0 0 2 2 2 1 zinc-ribbon domain Prok-RING_1 PF14446.1 ABX13190.1 - 0.0014 18.2 2.2 0.0032 17.1 1.5 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C4_Topoisom PF01396.14 ABX13190.1 - 0.0016 17.8 0.4 0.25 10.8 0.0 2.1 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger zf-RING_3 PF14369.1 ABX13190.1 - 0.0028 17.6 1.1 0.004 17.1 0.8 1.2 1 0 0 1 1 1 1 zinc-finger DNA_RNApol_7kD PF03604.8 ABX13190.1 - 0.0037 16.6 2.8 0.012 15.1 2.0 1.7 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-HYPF PF07503.7 ABX13190.1 - 0.0068 15.7 1.6 0.05 13.0 1.1 1.9 1 1 0 1 1 1 1 HypF finger A2L_zn_ribbon PF08792.5 ABX13190.1 - 0.01 15.2 1.6 0.076 12.4 0.1 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain HypA PF01155.14 ABX13190.1 - 0.019 14.6 0.2 0.02 14.5 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 ABX13190.1 - 0.02 14.5 1.1 0.47 10.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 TerY-C PF15616.1 ABX13190.1 - 0.023 14.6 0.2 0.028 14.3 0.1 1.4 1 1 0 1 1 1 0 TerY-C metal binding domain DZR PF12773.2 ABX13190.1 - 0.026 14.3 1.2 0.05 13.4 0.8 1.6 1 1 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 ABX13190.1 - 0.027 14.1 0.3 0.038 13.6 0.2 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-CSL PF05207.8 ABX13190.1 - 0.034 13.6 1.1 0.045 13.2 0.8 1.3 1 0 0 1 1 1 0 CSL zinc finger Zn-ribbon_8 PF09723.5 ABX13190.1 - 0.038 13.9 2.7 0.071 13.0 1.9 1.5 1 1 0 1 1 1 0 Zinc ribbon domain BssC_TutF PF08201.6 ABX13190.1 - 0.073 12.5 0.7 6 6.4 0.0 2.0 1 1 1 2 2 2 0 BssC/TutF protein zinc_ribbon_2 PF13240.1 ABX13190.1 - 0.088 12.3 2.9 0.78 9.3 2.0 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 ABX13190.1 - 0.094 12.6 1.0 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger RRN7 PF11781.3 ABX13190.1 - 0.11 12.0 2.2 0.25 10.8 0.1 2.0 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-IS66 PF13005.2 ABX13190.1 - 0.12 12.3 1.7 0.75 9.8 0.2 2.4 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Lar_restr_allev PF14354.1 ABX13190.1 - 0.14 12.4 1.5 0.82 10.0 1.1 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF35_N PF12172.3 ABX13190.1 - 0.16 11.8 0.6 3.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF164 PF02591.10 ABX13190.1 - 0.17 11.7 3.3 1 9.2 2.3 2.0 1 1 0 1 1 1 0 Putative zinc ribbon domain CpXC PF14353.1 ABX13190.1 - 0.18 11.7 1.4 0.96 9.4 0.1 2.0 1 1 1 2 2 2 0 CpXC protein TF_Zn_Ribbon PF08271.7 ABX13190.1 - 0.18 11.1 2.8 0.31 10.4 1.9 1.4 1 1 0 1 1 1 0 TFIIB zinc-binding DUF983 PF06170.7 ABX13190.1 - 0.24 11.5 0.6 9.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) XPA_N PF01286.13 ABX13190.1 - 0.26 10.9 2.8 10 5.9 0.0 2.1 2 0 0 2 2 2 0 XPA protein N-terminal DUF3797 PF12677.2 ABX13190.1 - 0.44 10.2 2.1 1 9.0 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-H2C2_2 PF13465.1 ABX13190.1 - 0.55 10.6 2.4 1.4 9.3 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger double domain DUF1272 PF06906.6 ABX13190.1 - 0.73 9.7 4.7 2.1 8.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) RimK PF08443.6 ABX13191.1 - 2.7e-44 150.9 0.0 3.8e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 ABX13191.1 - 1.4e-10 41.2 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 ABX13191.1 - 3.1e-09 36.9 0.1 4.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GSH-S_ATP PF02955.11 ABX13191.1 - 3.8e-07 29.3 0.0 5.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_Ter PF15632.1 ABX13191.1 - 3.2e-06 26.1 0.0 1.5e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 ABX13191.1 - 0.00034 20.0 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 ABX13191.1 - 0.00039 19.7 0.0 0.0014 17.9 0.0 1.8 1 1 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_5 PF13549.1 ABX13191.1 - 0.0077 15.4 0.1 0.025 13.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Peptidase_M20 PF01546.23 ABX13192.1 - 6.3e-30 104.1 0.1 7.9e-30 103.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ABX13192.1 - 5e-14 51.9 0.0 1.4e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 ABX13192.1 - 1.4e-05 24.0 0.7 0.065 11.9 0.1 2.5 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase Big_3 PF07523.7 ABX13192.1 - 0.027 14.5 0.2 0.077 13.0 0.2 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) TP_methylase PF00590.15 ABX13193.1 - 2.4e-19 69.9 0.0 1.3e-18 67.5 0.0 1.9 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF357 PF04010.8 ABX13193.1 - 3.4e-11 42.6 0.3 1.1e-10 41.0 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF357) Ala_racemase_C PF00842.16 ABX13193.1 - 0.05 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain CTP_transf_2 PF01467.21 ABX13194.1 - 5.8e-15 55.6 0.1 1.2e-14 54.6 0.1 1.5 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 ABX13194.1 - 0.0093 15.6 0.2 0.018 14.7 0.1 1.5 1 1 0 1 1 1 1 FAD synthetase Glyco_tran_WecB PF03808.8 ABX13194.1 - 0.056 12.8 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family HTH_27 PF13463.1 ABX13194.1 - 0.097 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain Urm1 PF09138.6 ABX13194.1 - 0.13 12.3 0.5 0.55 10.3 0.0 2.0 1 1 0 2 2 2 0 Urm1 (Ubiquitin related modifier) HATPase_c PF02518.21 ABX13195.1 - 3.3e-20 71.8 0.5 7.9e-20 70.6 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 ABX13195.1 - 7.6e-17 61.5 0.0 2.4e-16 60.0 0.0 1.9 1 0 0 1 1 1 1 PAS domain HAMP PF00672.20 ABX13195.1 - 1.6e-12 47.3 0.1 8.9e-12 45.0 0.0 2.3 2 0 0 2 2 2 1 HAMP domain PAS PF00989.19 ABX13195.1 - 5e-10 39.1 0.0 1.6e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold HisKA PF00512.20 ABX13195.1 - 8.3e-09 35.3 1.8 1.6e-08 34.4 0.2 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 ABX13195.1 - 4.9e-08 32.6 1.5 1.1e-07 31.4 0.2 2.2 2 0 0 2 2 2 1 GHKL domain PAS_3 PF08447.6 ABX13195.1 - 4.4e-07 29.9 0.0 2.2e-06 27.6 0.0 2.2 1 1 1 2 2 2 1 PAS fold PAS_4 PF08448.5 ABX13195.1 - 5.7e-05 23.1 0.0 0.00015 21.7 0.0 1.8 2 0 0 2 2 2 1 PAS fold 4HB_MCP_1 PF12729.2 ABX13195.1 - 0.0012 18.1 0.2 0.0012 18.1 0.2 4.0 4 0 0 4 4 4 2 Four helix bundle sensory module for signal transduction HATPase_c_3 PF13589.1 ABX13195.1 - 0.0014 18.3 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.1 ABX13195.1 - 0.0046 16.7 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.1 ABX13195.1 - 0.023 14.4 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Cep57_MT_bd PF06657.8 ABX13195.1 - 0.14 12.1 2.4 0.16 11.9 0.4 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Usp PF00582.21 ABX13196.1 - 3.2e-05 24.1 0.0 3.5e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family GST_C PF00043.20 ABX13196.1 - 0.014 15.3 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CTP-dep_RFKase PF01982.11 ABX13197.1 - 1.5e-43 147.3 0.0 2.1e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF120 HTH_36 PF13730.1 ABX13197.1 - 0.022 14.9 0.8 0.11 12.6 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.17 ABX13197.1 - 0.025 14.2 0.1 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 MarR family HicB PF05534.7 ABX13197.1 - 0.052 13.1 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 HicB family Peptidase_C42 PF05533.7 ABX13197.1 - 0.14 11.9 0.1 1 9.2 0.1 2.1 1 1 1 2 2 2 0 Beet yellows virus-type papain-like endopeptidase C42 Toprim_4 PF13662.1 ABX13198.1 - 1.5e-06 28.1 0.2 3.3e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.1 ABX13198.1 - 0.0094 16.2 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.17 ABX13198.1 - 0.017 15.0 0.1 0.053 13.4 0.1 1.9 1 0 0 1 1 1 0 Toprim domain Copper-fist PF00649.13 ABX13198.1 - 0.12 11.6 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 Copper fist DNA binding domain Fe-S_biosyn PF01521.15 ABX13199.1 - 1.2e-23 83.2 0.0 1.3e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis UPF0181 PF03701.9 ABX13199.1 - 0.099 11.9 0.0 2 7.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) CBS PF00571.23 ABX13200.1 - 1.1e-25 89.1 0.9 9.5e-12 44.5 0.0 2.1 2 0 0 2 2 2 2 CBS domain HicB PF05534.7 ABX13201.1 - 0.0067 15.9 0.2 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 HicB family HTH_20 PF12840.2 ABX13202.1 - 4e-05 23.3 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain FUR PF01475.14 ABX13202.1 - 0.00046 20.1 0.1 0.00056 19.8 0.1 1.2 1 0 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.14 ABX13202.1 - 0.00064 19.3 0.1 0.0015 18.1 0.1 1.7 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 ABX13202.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Copper-bind PF00127.15 ABX13203.1 - 1.5e-07 31.5 0.0 4e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 ABX13203.1 - 3.4e-05 23.6 0.0 6.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Cupredoxin-like domain DUF1616 PF07760.6 ABX13203.1 - 0.086 11.9 0.3 0.087 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) ECH PF00378.15 ABX13204.1 - 4.4e-72 242.1 2.1 4.9e-72 241.9 1.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 ABX13204.1 - 0.0066 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ATP-grasp_5 PF13549.1 ABX13205.1 - 8.9e-67 224.5 0.4 1.4e-66 223.9 0.3 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 ABX13205.1 - 3.4e-48 162.7 0.1 8.3e-48 161.5 0.1 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 ABX13205.1 - 7e-28 97.1 0.0 2.6e-27 95.2 0.0 2.1 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 ABX13205.1 - 3.1e-08 33.2 0.6 8.4e-08 31.8 0.4 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 ABX13205.1 - 0.00071 19.3 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain TPP_enzyme_M PF00205.17 ABX13205.1 - 0.0034 17.1 0.7 0.099 12.3 0.0 3.4 4 1 0 4 4 4 1 Thiamine pyrophosphate enzyme, central domain ATP-grasp PF02222.17 ABX13205.1 - 0.017 14.4 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain GATase PF00117.23 ABX13206.1 - 3.9e-24 85.1 0.0 5.2e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ABX13206.1 - 3.1e-08 33.3 0.0 5e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 ABX13206.1 - 0.041 13.4 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 ABX13206.1 - 0.055 12.9 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family TRADD_N PF09034.5 ABX13206.1 - 0.064 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain Toprim PF01751.17 ABX13207.1 - 1.5e-06 28.1 0.1 9.1e-06 25.5 0.1 2.0 1 1 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 ABX13207.1 - 1.2e-05 25.2 0.0 2.3e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Toprim domain Toprim_2 PF13155.1 ABX13207.1 - 0.013 15.7 0.0 0.018 15.3 0.0 1.4 1 1 0 1 1 1 0 Toprim-like FCH PF00611.18 ABX13207.1 - 0.075 13.2 0.3 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Toprim_3 PF13362.1 ABX13207.1 - 0.13 12.5 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Toprim domain ELFV_dehydrog PF00208.16 ABX13208.1 - 8.2e-68 228.6 2.3 1.2e-67 228.1 1.6 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 ABX13208.1 - 8.8e-48 161.1 0.0 1.5e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain HTH_17 PF12728.2 ABX13208.1 - 0.068 13.4 0.0 14 5.9 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain AlaDh_PNT_C PF01262.16 ABX13208.1 - 0.085 12.4 2.9 0.38 10.3 1.8 2.3 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 ABX13208.1 - 0.13 11.4 0.2 0.27 10.3 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HTH_5 PF01022.15 ABX13209.1 - 2.5e-11 43.0 0.3 5.6e-11 41.9 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 ABX13209.1 - 0.001 18.7 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 ABX13209.1 - 0.0056 16.0 0.1 0.022 14.1 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_45 PF14947.1 ABX13209.1 - 0.009 15.8 0.3 0.023 14.5 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.14 ABX13209.1 - 0.0097 15.5 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 ABX13209.1 - 0.0099 15.7 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_34 PF13601.1 ABX13209.1 - 0.018 15.0 0.9 0.048 13.6 0.0 2.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain Phage_rep_org_N PF09681.5 ABX13209.1 - 0.019 14.5 0.2 0.019 14.5 0.1 1.5 2 0 0 2 2 2 0 N-terminal phage replisome organiser (Phage_rep_org_N) HTH_12 PF08461.5 ABX13209.1 - 0.045 13.4 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Proteasome PF00227.21 ABX13210.1 - 2.4e-49 167.2 1.7 3e-49 166.8 1.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 ABX13210.1 - 6.7e-13 47.6 1.5 3.1e-11 42.3 0.1 2.5 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature DAZAP2 PF11029.3 ABX13210.1 - 0.052 14.0 0.6 0.11 12.9 0.2 1.7 1 1 1 2 2 2 0 DAZ associated protein 2 (DAZAP2) Ubie_methyltran PF01209.13 ABX13211.1 - 4.9e-18 65.0 0.0 6.1e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 ABX13211.1 - 4.2e-14 52.7 0.0 6.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ABX13211.1 - 1.5e-08 34.5 0.0 1.9e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX13211.1 - 1.1e-07 32.4 0.0 2e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ABX13211.1 - 2.1e-07 30.6 0.0 4.8e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ABX13211.1 - 1e-06 29.1 0.0 1.8e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ABX13211.1 - 2e-06 28.0 0.0 3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 ABX13211.1 - 0.007 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 ABX13211.1 - 0.016 14.5 0.0 0.031 13.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 ABX13211.1 - 0.029 14.3 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 ABX13211.1 - 0.089 11.8 0.0 0.14 11.1 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MFS_1 PF07690.11 ABX13212.1 - 3e-45 154.4 60.0 8.3e-34 116.8 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 ABX13212.1 - 0.00036 18.7 9.9 0.00064 17.9 6.9 1.4 1 1 0 1 1 1 1 Transmembrane secretion effector UNC-93 PF05978.11 ABX13212.1 - 0.34 10.3 11.1 0.035 13.6 0.6 2.7 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 DUF1228 PF06779.9 ABX13212.1 - 0.79 9.7 9.9 0.23 11.5 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) P-II PF00543.17 ABX13213.1 - 1.3e-17 64.1 0.3 2.5e-17 63.1 0.2 1.4 1 1 0 1 1 1 1 Nitrogen regulatory protein P-II HisG_C PF08029.6 ABX13213.1 - 0.033 14.1 0.9 0.2 11.6 0.4 2.0 2 0 0 2 2 2 0 HisG, C-terminal domain MttA_Hcf106 PF02416.11 ABX13214.1 - 4e-09 35.4 0.6 5.7e-09 34.9 0.4 1.4 1 1 0 1 1 1 1 mttA/Hcf106 family Laminin_II PF06009.7 ABX13214.1 - 0.01 15.6 0.3 0.014 15.1 0.2 1.3 1 1 0 1 1 1 0 Laminin Domain II PCYCGC PF13798.1 ABX13214.1 - 0.044 13.4 0.2 3.2 7.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function with PCYCGC motif IFT20 PF14931.1 ABX13214.1 - 0.052 13.4 0.9 0.068 13.0 0.7 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF948 PF06103.6 ABX13214.1 - 0.081 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4389 PF14333.1 ABX13214.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Lipase PF00151.14 ABX13214.1 - 0.096 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Lipase LLC1 PF14945.1 ABX13214.1 - 0.099 12.9 0.5 0.12 12.7 0.3 1.1 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein SSPI PF14098.1 ABX13214.1 - 0.14 12.1 2.5 0.19 11.6 0.2 2.0 2 0 0 2 2 2 0 Small, acid-soluble spore protein I N6_N4_Mtase PF01555.13 ABX13215.1 - 7.3e-40 136.8 4.9 8.7e-40 136.6 3.4 1.0 1 0 0 1 1 1 1 DNA methylase Methyltransf_26 PF13659.1 ABX13215.1 - 1.2e-08 34.9 0.0 0.0029 17.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain UPF0020 PF01170.13 ABX13215.1 - 3.2e-05 23.5 0.0 0.23 11.0 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 ABX13215.1 - 0.00033 19.8 0.1 0.048 12.7 0.1 2.1 2 0 0 2 2 2 2 N-6 DNA Methylase MethyltransfD12 PF02086.10 ABX13215.1 - 0.00076 19.0 0.3 0.004 16.6 0.0 2.1 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase DEAD PF00270.24 ABX13216.1 - 5.9e-33 113.7 0.6 5.6e-32 110.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ABX13216.1 - 7.1e-15 54.6 0.5 2.2e-10 40.2 0.1 3.4 4 0 0 4 4 4 2 Helicase conserved C-terminal domain DUF1998 PF09369.5 ABX13216.1 - 4.7e-12 46.3 0.1 1.1e-11 45.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) ResIII PF04851.10 ABX13216.1 - 3e-05 23.9 0.4 3e-05 23.9 0.2 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 ABX13216.1 - 0.0002 20.2 0.1 0.00033 19.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain adh_short PF00106.20 ABX13217.1 - 6.4e-30 104.2 0.0 8.1e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ABX13217.1 - 1.2e-21 77.5 0.0 1.5e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ABX13217.1 - 2.8e-10 40.1 0.0 4.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 ABX13217.1 - 8.9e-08 31.6 0.1 4.7e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family DUF1776 PF08643.5 ABX13217.1 - 4.5e-05 22.7 0.0 8.3e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 ABX13217.1 - 0.0026 17.5 0.2 0.0061 16.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 ABX13217.1 - 0.056 12.8 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Topoisom_I_N PF02919.10 ABX13218.1 - 2.4e-72 242.7 8.4 2.4e-72 242.7 5.8 3.1 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 ABX13218.1 - 7.2e-66 221.6 17.3 7.2e-66 221.6 12.0 2.2 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 ABX13218.1 - 8.2e-23 79.8 1.9 8.2e-23 79.8 1.4 4.0 4 0 0 4 4 4 1 C-terminal topoisomerase domain Phage_integrase PF00589.17 ABX13220.1 - 2.2e-12 47.0 0.1 5e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family zf-ribbon_3 PF13248.1 ABX13220.1 - 0.0098 15.0 3.1 0.021 13.9 2.2 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 ABX13220.1 - 0.13 11.7 3.2 0.27 10.7 2.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 ABX13220.1 - 0.13 12.0 3.9 0.048 13.4 0.8 1.6 2 0 0 2 2 2 0 Double zinc ribbon zf-RanBP PF00641.13 ABX13220.1 - 0.33 10.0 2.7 0.54 9.4 1.9 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others FYDLN_acid PF09538.5 ABX13220.1 - 0.47 11.0 5.0 0.13 12.8 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TSP_3 PF02412.13 ABX13221.1 - 3.8e-08 32.6 36.2 0.00047 19.5 1.1 3.7 3 0 0 3 3 3 3 Thrombospondin type 3 repeat DUF3121 PF11319.3 ABX13221.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) HTH_24 PF13412.1 ABX13222.1 - 2.2e-15 55.7 0.7 1.2e-07 31.0 0.0 2.8 4 0 0 4 4 3 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 ABX13222.1 - 4.4e-13 48.6 0.4 6.3e-09 35.3 0.1 2.4 2 1 0 2 2 2 2 Bacterial regulatory protein, arsR family TrmB PF01978.14 ABX13222.1 - 2.6e-12 46.2 0.2 2.4e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 ABX13222.1 - 3.1e-10 39.7 0.0 8.1e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_34 PF13601.1 ABX13222.1 - 5.1e-08 32.8 0.2 0.003 17.5 0.0 2.2 2 0 0 2 2 2 2 Winged helix DNA-binding domain FaeA PF04703.7 ABX13222.1 - 2.7e-07 30.6 0.2 0.00036 20.6 0.0 2.8 2 1 1 3 3 3 1 FaeA-like protein MarR PF01047.17 ABX13222.1 - 1.1e-06 28.2 0.3 0.0034 17.0 0.1 2.4 2 0 0 2 2 2 2 MarR family z-alpha PF02295.12 ABX13222.1 - 3.9e-06 26.5 0.1 6.8e-05 22.5 0.0 2.6 3 0 0 3 3 3 1 Adenosine deaminase z-alpha domain MarR_2 PF12802.2 ABX13222.1 - 5.9e-06 25.8 0.0 0.0076 15.9 0.0 2.2 2 0 0 2 2 2 2 MarR family HTH_11 PF08279.7 ABX13222.1 - 1.4e-05 24.6 0.1 0.0031 17.1 0.0 2.4 2 0 0 2 2 2 1 HTH domain HTH_IclR PF09339.5 ABX13222.1 - 9.6e-05 21.8 0.0 0.37 10.4 0.0 2.3 2 0 0 2 2 2 2 IclR helix-turn-helix domain Penicillinase_R PF03965.11 ABX13222.1 - 0.00018 21.5 2.6 0.00098 19.1 0.2 2.2 1 1 1 2 2 2 1 Penicillinase repressor RepL PF05732.6 ABX13222.1 - 0.0002 20.6 0.0 0.0097 15.1 0.0 2.2 2 0 0 2 2 2 1 Firmicute plasmid replication protein (RepL) HTH_Crp_2 PF13545.1 ABX13222.1 - 0.00032 20.4 0.0 0.039 13.7 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain LexA_DNA_bind PF01726.11 ABX13222.1 - 0.00043 19.7 0.2 0.69 9.5 0.0 2.9 2 2 1 3 3 3 2 LexA DNA binding domain GerE PF00196.14 ABX13222.1 - 0.0014 17.8 0.1 0.03 13.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family PadR PF03551.9 ABX13222.1 - 0.0018 17.9 1.9 0.03 14.0 0.1 2.5 2 1 0 2 2 2 1 Transcriptional regulator PadR-like family HTH_40 PF14493.1 ABX13222.1 - 0.002 18.2 0.2 0.2 11.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Rrf2 PF02082.15 ABX13222.1 - 0.0032 17.5 0.2 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator HTH_27 PF13463.1 ABX13222.1 - 0.0055 17.0 0.0 0.12 12.7 0.0 2.1 2 0 0 2 2 2 1 Winged helix DNA-binding domain FUR PF01475.14 ABX13222.1 - 0.0083 16.0 3.5 0.083 12.8 0.3 2.5 1 1 1 2 2 2 1 Ferric uptake regulator family DUF4364 PF14277.1 ABX13222.1 - 0.0095 15.5 2.7 0.049 13.2 0.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4364) HTH_9 PF08221.6 ABX13222.1 - 0.0098 15.7 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF4423 PF14394.1 ABX13222.1 - 0.01 15.3 0.2 2.4 7.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4423) Sigma70_r4 PF04545.11 ABX13222.1 - 0.021 14.1 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_41 PF14502.1 ABX13222.1 - 0.036 13.6 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain RPA_C PF08784.6 ABX13222.1 - 0.043 14.2 0.1 0.38 11.2 0.0 2.1 2 0 0 2 2 2 0 Replication protein A C terminal Phage_rep_org_N PF09681.5 ABX13222.1 - 0.049 13.1 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 N-terminal phage replisome organiser (Phage_rep_org_N) HTH_38 PF13936.1 ABX13222.1 - 0.053 13.0 0.1 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.14 ABX13222.1 - 0.065 13.1 0.5 0.97 9.4 0.0 2.4 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain DUF2250 PF10007.4 ABX13222.1 - 0.074 12.9 2.0 6.1 6.8 0.3 2.7 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Sigma70_r4_2 PF08281.7 ABX13222.1 - 0.077 12.4 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 PaaX PF07848.7 ABX13222.1 - 0.1 12.6 0.0 20 5.2 0.0 2.3 2 0 0 2 2 2 0 PaaX-like protein HTH_10 PF04967.7 ABX13222.1 - 0.14 11.7 0.2 1.7 8.2 0.0 2.6 3 0 0 3 3 2 0 HTH DNA binding domain ER_lumen_recept PF00810.13 ABX13223.1 - 0.0091 16.4 2.6 0.011 16.2 1.8 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF373 PF04123.8 ABX13223.1 - 0.01 14.8 2.5 0.012 14.6 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2975 PF11188.3 ABX13223.1 - 0.096 12.4 5.8 1.8 8.2 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF1352 PF07086.7 ABX13223.1 - 0.16 11.6 1.1 0.21 11.2 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1352) PrgI PF12666.2 ABX13223.1 - 1.8 8.7 4.9 15 5.7 3.4 2.1 1 1 0 1 1 1 0 PrgI family protein A2M_N PF01835.14 ABX13224.1 - 3.1e-18 65.8 0.4 7.2e-06 26.1 0.0 4.2 4 0 0 4 4 4 3 MG2 domain FlgD_ig PF13860.1 ABX13224.1 - 3.7e-05 23.3 3.5 1 9.1 0.1 4.2 4 0 0 4 4 4 3 FlgD Ig-like domain DUF3244 PF11589.3 ABX13224.1 - 0.00014 21.5 4.2 0.012 15.3 0.1 3.6 3 1 0 3 3 3 2 Domain of unknown function (DUF3244) CarboxypepD_reg PF13620.1 ABX13225.1 - 0.00072 19.5 0.1 0.0013 18.7 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 ABX13225.1 - 0.055 13.4 0.6 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4198) HSP70 PF00012.15 ABX13225.1 - 0.11 10.4 10.9 0.12 10.2 7.3 1.3 1 1 0 1 1 1 0 Hsp70 protein Pox_A_type_inc PF04508.7 ABX13226.1 - 0.26 11.1 1.5 0.57 10.1 0.2 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Glyco_transf_15 PF01793.11 ABX13226.1 - 1.3 7.8 6.8 0.69 8.7 3.7 1.3 1 1 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase ParBc PF02195.13 ABX13227.1 - 2.4e-19 69.1 0.2 5.3e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain DUF2924 PF11149.3 ABX13227.1 - 0.16 12.0 3.3 0.11 12.5 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2924) Usp PF00582.21 ABX13228.1 - 2.1e-12 47.4 0.0 2.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF1044 PF06296.7 ABX13228.1 - 0.023 14.5 0.3 0.043 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1044) DUF262 PF03235.9 ABX13229.1 - 0.05 13.5 6.4 0.062 13.2 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF3260 PF11658.3 ABX13229.1 - 0.073 11.2 0.2 0.088 10.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) IncA PF04156.9 ABX13229.1 - 0.23 11.0 10.0 0.27 10.8 6.9 1.1 1 0 0 1 1 1 0 IncA protein Nnf1 PF03980.9 ABX13229.1 - 0.39 10.7 10.3 0.89 9.5 7.1 1.7 1 1 0 1 1 1 0 Nnf1 Asp-B-Hydro_N PF05279.6 ABX13229.1 - 0.48 10.2 5.7 0.59 9.9 3.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3450 PF11932.3 ABX13229.1 - 0.96 8.6 10.1 7.1 5.8 7.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DNA_topoisoIV PF00521.15 ABX13229.1 - 2.7 6.7 12.6 3.2 6.5 8.7 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A UPF0449 PF15136.1 ABX13229.1 - 2.7 8.2 10.2 0.6 10.3 2.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF1664 PF07889.7 ABX13229.1 - 3 7.6 10.9 7.2 6.4 7.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMCO5 PF14992.1 ABX13229.1 - 3.9 6.5 16.6 13 4.7 11.5 1.7 1 1 0 1 1 1 0 TMCO5 family YlqD PF11068.3 ABX13229.1 - 6 6.9 17.6 1.9 8.5 5.8 2.1 1 1 1 2 2 2 0 YlqD protein Med9 PF07544.8 ABX13229.1 - 8.2 6.2 16.5 1.8e+02 1.9 11.3 2.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Usp PF00582.21 ABX13230.1 - 1.9e-20 73.4 0.0 2.1e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Dishevelled PF02377.10 ABX13230.1 - 0.063 13.4 0.0 0.089 13.0 0.0 1.2 1 0 0 1 1 1 0 Dishevelled specific domain G-gamma PF00631.17 ABX13230.1 - 0.098 12.4 0.4 0.24 11.1 0.3 1.7 1 1 0 1 1 1 0 GGL domain Aminotran_4 PF01063.14 ABX13230.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class IV B12-binding PF02310.14 ABX13230.1 - 0.13 12.1 0.0 0.52 10.2 0.0 1.9 1 1 0 1 1 1 0 B12 binding domain MS_channel PF00924.13 ABX13231.1 - 6.7e-50 169.2 0.3 6.7e-50 169.2 0.2 1.5 2 0 0 2 2 2 1 Mechanosensitive ion channel Ni_hydr_CYTB PF01292.15 ABX13231.1 - 0.013 14.8 0.8 0.026 13.9 0.6 1.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Cytochrom_B_N PF00033.14 ABX13231.1 - 0.035 13.4 1.6 0.072 12.4 1.1 1.5 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF432 PF04254.8 ABX13232.1 - 1.1e-24 86.7 0.0 1.6e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF432) VirK PF06903.7 ABX13232.1 - 0.12 12.1 0.8 2.8 7.7 0.1 3.1 3 1 1 4 4 4 0 VirK protein MS_channel PF00924.13 ABX13233.1 - 2.3e-16 59.7 2.6 2.6e-16 59.5 1.8 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel ParcG PF10274.4 ABX13233.1 - 0.003 17.4 0.0 0.0034 17.2 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein HTH_45 PF14947.1 ABX13234.1 - 3.3e-05 23.6 0.0 0.00013 21.6 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix MarR_2 PF12802.2 ABX13234.1 - 0.0006 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.1 ABX13234.1 - 0.0015 17.8 0.1 0.0084 15.4 0.1 2.4 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 ABX13234.1 - 0.0017 18.6 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4423 PF14394.1 ABX13234.1 - 0.002 17.6 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_20 PF12840.2 ABX13234.1 - 0.0045 16.7 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 ABX13234.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HxlR PF01638.12 ABX13234.1 - 0.016 14.8 0.1 0.047 13.3 0.1 1.9 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DUF1724 PF08350.5 ABX13234.1 - 0.016 14.7 0.1 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) Rrf2 PF02082.15 ABX13234.1 - 0.028 14.5 0.1 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator DUF2042 PF09743.4 ABX13234.1 - 0.031 13.5 0.3 0.051 12.8 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) AsnC_trans_reg PF01037.16 ABX13235.1 - 0.00073 19.1 0.0 0.00091 18.8 0.0 1.2 1 0 0 1 1 1 1 AsnC family TFIIB PF00382.14 ABX13236.1 - 5.2e-37 125.4 9.9 1e-20 73.2 1.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 ABX13236.1 - 2.8e-10 39.3 1.9 4.7e-10 38.6 1.3 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 ABX13236.1 - 1.4e-06 27.9 0.8 0.00028 20.4 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 ABX13236.1 - 3.6e-06 25.9 0.7 6.9e-06 25.1 0.5 1.4 1 0 0 1 1 1 1 zinc-ribbon domain Sigma70_r4 PF04545.11 ABX13236.1 - 6e-06 25.4 0.1 0.019 14.2 0.0 2.9 2 0 0 2 2 2 2 Sigma-70, region 4 Ribosomal_S27e PF01667.12 ABX13236.1 - 0.00089 18.7 1.2 0.0018 17.7 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 HTH_3 PF01381.17 ABX13236.1 - 0.0026 17.5 0.1 0.46 10.3 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix Lar_restr_allev PF14354.1 ABX13236.1 - 0.0037 17.5 0.6 0.01 16.0 0.4 1.7 1 0 0 1 1 1 1 Restriction alleviation protein Lar DZR PF12773.2 ABX13236.1 - 0.004 16.9 0.4 0.0091 15.8 0.3 1.6 1 0 0 1 1 1 1 Double zinc ribbon HTH_11 PF08279.7 ABX13236.1 - 0.0043 16.6 1.8 0.02 14.5 0.0 2.6 3 0 0 3 3 3 1 HTH domain RB_B PF01857.15 ABX13236.1 - 0.01 15.3 0.2 0.017 14.6 0.2 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain HTH_AsnC-type PF13404.1 ABX13236.1 - 0.011 15.2 1.6 0.2 11.2 0.0 3.0 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain DUF329 PF03884.9 ABX13236.1 - 0.023 14.2 0.5 0.061 12.8 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF329) HTH_24 PF13412.1 ABX13236.1 - 0.03 13.6 0.4 0.61 9.5 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HrcA_DNA-bdg PF03444.10 ABX13236.1 - 0.12 11.7 1.1 6.2 6.3 0.0 3.0 2 1 1 3 3 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding GerE PF00196.14 ABX13236.1 - 0.13 11.6 2.8 1.1 8.6 0.0 3.2 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.7 ABX13236.1 - 0.14 11.6 4.3 0.16 11.4 0.0 3.1 4 0 0 4 4 4 0 Sigma-70, region 4 Zn-ribbon_8 PF09723.5 ABX13236.1 - 0.22 11.5 2.2 0.79 9.7 0.2 2.5 1 1 1 2 2 2 0 Zinc ribbon domain FYDLN_acid PF09538.5 ABX13236.1 - 0.24 11.9 1.3 1.7 9.2 0.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_2 PF13240.1 ABX13236.1 - 0.32 10.5 7.3 9.5 5.8 5.2 2.3 1 1 1 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 ABX13236.1 - 0.35 10.5 2.9 0.24 11.1 0.3 2.1 2 0 0 2 2 1 0 Putative transposase DNA-binding domain Mu-like_Com PF10122.4 ABX13236.1 - 0.82 8.7 4.3 0.33 10.0 0.4 2.3 2 1 0 2 2 2 0 Mu-like prophage protein Com UPF0547 PF10571.4 ABX13236.1 - 3.6 7.3 5.5 29 4.4 0.7 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 TFIIB PF00382.14 ABX13237.1 - 1.1e-24 86.0 1.6 1.8e-11 43.6 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_N PF00134.18 ABX13237.1 - 0.0013 18.2 0.2 0.41 10.2 0.1 2.2 1 1 1 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 ABX13237.1 - 0.0037 16.5 2.4 0.0071 15.6 1.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_36 PF13730.1 ABX13237.1 - 0.012 15.7 0.4 0.9 9.7 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 ABX13237.1 - 0.026 13.8 0.3 0.49 9.7 0.0 3.1 4 1 0 4 4 4 0 Sigma-70, region 4 HTH_23 PF13384.1 ABX13237.1 - 0.036 13.7 0.6 0.82 9.4 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Mga PF08280.6 ABX13237.1 - 0.075 12.8 0.0 0.74 9.6 0.0 2.6 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Rrf2 PF02082.15 ABX13237.1 - 0.097 12.7 0.1 0.64 10.1 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator HTH_27 PF13463.1 ABX13237.1 - 0.13 12.5 0.4 0.52 10.6 0.0 2.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain MS_channel PF00924.13 ABX13238.1 - 5.3e-08 32.4 2.0 5.3e-08 32.4 1.4 1.5 2 0 0 2 2 2 1 Mechanosensitive ion channel DUF2871 PF11070.3 ABX13238.1 - 0.36 10.9 4.9 0.52 10.4 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2871) PhyH PF05721.8 ABX13239.1 - 9.5e-34 117.2 0.0 1.1e-33 117.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ectoine_synth PF06339.7 ABX13240.1 - 4e-58 194.8 0.1 4.5e-58 194.6 0.0 1.0 1 0 0 1 1 1 1 Ectoine synthase Cupin_2 PF07883.6 ABX13240.1 - 1.9e-06 27.2 0.3 2.6e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 ABX13240.1 - 0.021 14.4 0.1 0.028 14.1 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.7 ABX13240.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Pirin_C PF05726.8 ABX13240.1 - 0.033 14.2 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Pirin C-terminal cupin domain Aminotran_3 PF00202.16 ABX13241.1 - 3.2e-74 249.7 0.0 4.2e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Acetyltransf_1 PF00583.19 ABX13242.1 - 3.5e-09 36.5 0.0 4.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ABX13242.1 - 4.4e-07 29.9 0.0 6.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ABX13242.1 - 5.8e-06 26.4 0.0 7.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ABX13242.1 - 0.00029 20.9 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ABX13242.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 ABX13242.1 - 0.047 13.5 0.0 0.092 12.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1287 PF06940.6 ABX13243.1 - 0.051 12.9 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) eIF-1a PF01176.14 ABX13244.1 - 2.5e-18 65.2 2.2 3.2e-18 64.9 1.5 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 HAMP PF00672.20 ABX13245.1 - 2.8e-14 53.0 1.1 4.3e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 HAMP domain Guanylate_cyc PF00211.15 ABX13245.1 - 2.2e-07 30.4 0.0 4.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ribosomal_S22 PF08136.6 ABX13246.1 - 0.072 13.2 0.2 0.14 12.3 0.1 1.6 2 0 0 2 2 2 0 30S ribosomal protein subunit S22 family 7TM_GPCR_Srj PF10319.4 ABX13247.1 - 0.00028 20.1 1.3 0.00032 19.9 0.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj Sulfate_transp PF00916.15 ABX13247.1 - 0.13 11.2 1.4 0.14 11.1 0.9 1.2 1 0 0 1 1 1 0 Sulfate transporter family HTH_20 PF12840.2 ABX13248.1 - 2.6e-07 30.3 0.1 1.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.15 ABX13248.1 - 4.5e-07 29.4 0.2 8.4e-06 25.3 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 ABX13248.1 - 4.6e-05 23.0 0.0 0.0034 16.9 0.0 2.2 2 0 0 2 2 2 1 MarR family TrmB PF01978.14 ABX13248.1 - 0.0014 18.2 0.0 0.022 14.4 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 ABX13248.1 - 0.02 14.2 0.1 0.044 13.1 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 ABX13248.1 - 0.025 14.2 0.1 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 MarR family DUF2250 PF10007.4 ABX13248.1 - 0.028 14.3 0.3 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Hemerythrin PF01814.18 ABX13249.1 - 2.2e-12 47.2 2.5 2.2e-12 47.2 1.7 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain YqcI_YcgG PF08892.6 ABX13249.1 - 0.021 14.3 0.5 0.036 13.6 0.3 1.5 1 1 0 1 1 1 0 YqcI/YcgG family TLD PF07534.11 ABX13249.1 - 0.046 13.7 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 TLD Cu-oxidase_3 PF07732.10 ABX13250.1 - 3.1e-25 88.2 4.3 1.9e-23 82.4 0.1 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ABX13250.1 - 4.1e-13 49.0 10.7 4.1e-05 23.1 0.4 3.9 4 1 0 4 4 4 3 Multicopper oxidase Copper-bind PF00127.15 ABX13250.1 - 1.1e-10 41.5 2.5 1.4e-05 25.2 0.0 3.9 3 1 0 3 3 3 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 ABX13250.1 - 1e-09 38.2 0.0 2.3e-05 24.2 0.0 3.4 3 0 0 3 3 3 2 Cupredoxin-like domain COX2 PF00116.15 ABX13250.1 - 0.014 15.2 2.0 0.3 10.9 0.3 2.9 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, periplasmic domain Flavodoxin_1 PF00258.20 ABX13252.1 - 1.2e-21 77.2 0.1 1.4e-21 77.0 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.2 ABX13252.1 - 0.0087 15.4 0.0 0.012 14.9 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin domain Flavodoxin_5 PF12724.2 ABX13252.1 - 0.038 13.9 0.0 0.15 12.0 0.0 1.9 2 1 0 2 2 2 0 Flavodoxin domain Nitroreductase PF00881.19 ABX13253.1 - 1.7e-29 102.7 0.0 2.6e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family Lactamase_B PF00753.22 ABX13254.1 - 1.3e-09 37.9 1.1 2.1e-09 37.2 0.8 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Kazal_1 PF00050.16 ABX13254.1 - 1e-08 35.0 0.4 1e-08 35.0 0.3 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 ABX13254.1 - 1.7e-07 31.0 1.3 4.4e-07 29.7 0.9 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Lactamase_B_2 PF12706.2 ABX13254.1 - 0.0035 16.9 0.9 0.012 15.1 0.6 1.9 1 1 1 2 2 2 1 Beta-lactamase superfamily domain NOA36 PF06524.7 ABX13254.1 - 0.042 13.1 0.2 0.091 12.0 0.1 1.5 1 0 0 1 1 1 0 NOA36 protein HTH_5 PF01022.15 ABX13255.1 - 5.5e-08 32.3 0.2 1.1e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 ABX13255.1 - 7.1e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 ABX13255.1 - 6.7e-06 25.3 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 ABX13255.1 - 0.00045 19.8 0.1 0.00081 18.9 0.0 1.5 1 0 0 1 1 1 1 HTH domain Uroplakin_II PF07353.7 ABX13255.1 - 0.0017 17.7 0.1 0.0029 16.9 0.1 1.5 1 0 0 1 1 1 1 Uroplakin II TFIIE_alpha PF02002.12 ABX13255.1 - 0.0072 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 TFIIE alpha subunit SPOC PF07744.8 ABX13255.1 - 0.0095 16.4 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 SPOC domain Rifin_STEVOR PF02009.11 ABX13255.1 - 0.054 13.1 0.2 0.068 12.8 0.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family TrmB PF01978.14 ABX13255.1 - 0.09 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Mga PF05043.8 ABX13255.1 - 0.095 12.9 0.4 0.18 12.1 0.3 1.4 1 0 0 1 1 1 0 Mga helix-turn-helix domain SIMPL PF04402.9 ABX13256.1 - 7.2e-45 153.4 2.6 9.1e-45 153.0 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) TrmB PF01978.14 ABX13258.1 - 7.5e-05 22.3 0.2 0.00021 20.9 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 ABX13258.1 - 0.01 15.2 0.4 0.027 13.8 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 ABX13258.1 - 0.02 14.5 0.1 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_IclR PF09339.5 ABX13258.1 - 0.049 13.2 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain zf-ribbon_3 PF13248.1 ABX13260.1 - 0.0023 17.1 0.7 0.0037 16.4 0.1 1.7 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 ABX13260.1 - 0.0086 15.5 0.3 0.021 14.3 0.2 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zf-FCS PF06467.9 ABX13260.1 - 0.19 11.4 4.0 1.9 8.1 0.1 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Cys_rich_CPXG PF14255.1 ABX13260.1 - 0.22 11.3 0.9 0.22 11.3 0.6 2.1 2 1 0 2 2 2 0 Cysteine-rich CPXCG Cupredoxin_1 PF13473.1 ABX13261.1 - 2.9e-05 23.8 0.1 3.7e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Methyltransf_23 PF13489.1 ABX13262.1 - 1.4e-09 37.8 0.0 2.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ABX13262.1 - 5.1e-08 33.2 0.0 9.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ABX13262.1 - 4e-06 27.2 0.0 1.1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ABX13262.1 - 8.5e-06 25.4 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Trm112p PF03966.11 ABX13262.1 - 6.4e-05 23.2 0.3 0.00067 19.9 0.2 2.3 2 0 0 2 2 2 1 Trm112p-like protein MTS PF05175.9 ABX13262.1 - 0.00059 19.2 0.0 0.0012 18.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 ABX13262.1 - 0.0032 16.3 0.1 0.0054 15.6 0.1 1.4 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_25 PF13649.1 ABX13262.1 - 0.0033 17.7 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 ABX13262.1 - 0.005 16.2 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Elf1 PF05129.8 ABX13262.1 - 0.037 13.7 0.3 0.075 12.7 0.2 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-DNA_Pol PF08996.5 ABX13262.1 - 0.05 12.9 0.3 0.12 11.6 0.2 1.6 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Methyltransf_26 PF13659.1 ABX13262.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain zf-CSL PF05207.8 ABX13262.1 - 0.072 12.6 0.9 0.14 11.6 0.6 1.5 1 0 0 1 1 1 0 CSL zinc finger A2L_zn_ribbon PF08792.5 ABX13262.1 - 0.11 11.9 0.7 0.49 9.9 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_5 PF13719.1 ABX13262.1 - 0.18 11.4 1.3 0.44 10.1 0.9 1.7 1 1 0 1 1 1 0 zinc-ribbon domain NADPH_Ox PF08414.5 ABX13263.1 - 0.007 16.4 1.4 0.064 13.3 0.1 2.9 2 1 1 3 3 3 1 Respiratory burst NADPH oxidase Transglut_core2 PF13369.1 ABX13264.1 - 2e-39 134.4 0.0 3.4e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.1 ABX13264.1 - 5.9e-17 61.2 0.0 9.4e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ABX13264.1 - 2.5e-06 27.2 0.3 0.067 13.0 0.1 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 ABX13264.1 - 2e-05 23.9 1.0 0.0048 16.4 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 ABX13264.1 - 0.0001 21.9 0.1 0.0088 15.8 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ABX13264.1 - 0.00078 19.3 0.0 0.0015 18.4 0.0 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 ABX13264.1 - 0.0011 18.5 0.9 0.0054 16.4 0.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ABX13264.1 - 0.0013 18.2 0.1 0.0034 16.9 0.1 1.7 1 1 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 ABX13264.1 - 0.018 15.6 0.0 0.4 11.4 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat YfzA PF14118.1 ABX13264.1 - 0.095 12.8 0.2 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 YfzA-like protein DivIC PF04977.10 ABX13265.1 - 0.0039 16.6 1.5 0.0058 16.0 1.1 1.4 1 1 0 1 1 1 1 Septum formation initiator HCR PF07111.7 ABX13265.1 - 0.06 11.3 0.1 0.065 11.2 0.0 1.0 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) DUF904 PF06005.7 ABX13265.1 - 0.077 13.2 0.3 0.085 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TSC22 PF01166.13 ABX13265.1 - 0.1 12.5 0.9 0.17 11.8 0.6 1.4 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF1192 PF06698.6 ABX13265.1 - 0.1 12.3 2.7 0.29 10.9 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) bZIP_2 PF07716.10 ABX13265.1 - 0.14 11.9 1.1 0.23 11.3 0.1 1.7 1 1 1 2 2 2 0 Basic region leucine zipper MethyTransf_Reg PF10119.4 ABX13266.1 - 0.22 12.0 8.4 6.5 7.3 0.0 4.7 4 1 1 5 5 5 0 Predicted methyltransferase regulatory domain SATase_N PF06426.9 ABX13266.1 - 3.4 7.9 10.3 8.3 6.7 0.1 4.4 2 2 1 3 3 3 0 Serine acetyltransferase, N-terminal Cation_efflux PF01545.16 ABX13267.1 - 1.8e-18 66.6 12.8 3.9e-17 62.2 8.9 2.0 1 1 0 1 1 1 1 Cation efflux family IncA PF04156.9 ABX13267.1 - 0.92 9.0 7.2 5.5 6.5 1.3 2.3 2 0 0 2 2 2 0 IncA protein DUF2752 PF10825.3 ABX13267.1 - 0.97 9.5 3.7 3.7 7.6 2.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2752) HTH_5 PF01022.15 ABX13268.1 - 4.7e-15 54.9 1.0 1.5e-14 53.3 0.5 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 ABX13268.1 - 3.4e-08 33.1 0.0 5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 ABX13268.1 - 1.3e-06 27.9 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 ABX13268.1 - 7e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.1 ABX13268.1 - 0.00015 21.7 0.1 0.00021 21.2 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.5 ABX13268.1 - 0.00071 19.1 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_45 PF14947.1 ABX13268.1 - 0.0012 18.5 0.2 0.002 17.8 0.1 1.4 1 1 0 1 1 1 1 Winged helix-turn-helix HTH_27 PF13463.1 ABX13268.1 - 0.0047 17.2 0.0 0.0075 16.5 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF1495 PF07381.6 ABX13268.1 - 0.0086 15.7 0.1 0.17 11.5 0.1 2.1 1 1 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) HTH_24 PF13412.1 ABX13268.1 - 0.012 14.9 0.2 0.024 13.9 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF4423 PF14394.1 ABX13268.1 - 0.028 13.9 0.1 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Fe_dep_repress PF01325.14 ABX13268.1 - 0.03 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.17 ABX13268.1 - 0.039 13.6 0.3 0.084 12.5 0.2 1.7 1 1 0 1 1 1 0 MarR family RP-C PF03428.8 ABX13268.1 - 0.052 12.9 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain TFIIE_alpha PF02002.12 ABX13268.1 - 0.061 12.8 0.1 0.094 12.2 0.1 1.4 1 1 0 1 1 1 0 TFIIE alpha subunit B-block_TFIIIC PF04182.7 ABX13268.1 - 0.095 12.5 0.2 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_9 PF08221.6 ABX13268.1 - 0.1 12.5 0.3 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DoxX PF07681.7 ABX13269.1 - 1.1 9.6 5.8 1.5 9.3 4.0 1.3 1 1 0 1 1 1 0 DoxX YmzC PF14157.1 ABX13272.1 - 0.015 15.0 2.1 0.048 13.4 1.4 1.9 1 0 0 1 1 1 0 YmzC-like protein Phage_integrase PF00589.17 ABX13273.1 - 5.1e-07 29.5 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Metallophos_2 PF12850.2 ABX13274.1 - 6.6e-21 74.7 0.1 9.2e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ABX13274.1 - 3.2e-17 62.6 0.1 4.2e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 ABX13274.1 - 0.00013 21.2 0.1 0.0015 17.7 0.0 2.2 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily DUF2124 PF09897.4 ABX13274.1 - 0.00022 20.9 0.0 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2124) Iso_dh PF00180.15 ABX13275.1 - 2.5e-79 266.7 0.3 3e-79 266.5 0.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1906 PF08924.6 ABX13275.1 - 0.029 14.2 0.2 0.068 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) MTS PF05175.9 ABX13276.1 - 4.3e-13 48.9 0.0 6.1e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 ABX13276.1 - 5.2e-11 42.3 1.0 7.9e-11 41.7 0.7 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ABX13276.1 - 1.6e-08 34.3 0.0 2.7e-07 30.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ABX13276.1 - 3.5e-06 27.3 0.1 1.4e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ABX13276.1 - 4.2e-06 26.7 0.0 8e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX13276.1 - 1.1e-05 25.9 0.0 1.9e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ABX13276.1 - 0.00036 20.9 0.2 0.0011 19.3 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 ABX13276.1 - 0.00061 18.7 0.0 0.00086 18.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.14 ABX13276.1 - 0.0012 18.4 0.0 0.0051 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 ABX13276.1 - 0.0023 17.5 0.0 0.0047 16.5 0.0 1.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 ABX13276.1 - 0.0026 16.8 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 ABX13276.1 - 0.004 16.8 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ABX13276.1 - 0.0051 17.1 0.1 0.025 14.9 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 ABX13276.1 - 0.052 13.5 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.15 ABX13277.1 - 2.3e-39 135.0 2.7 2.7e-39 134.8 1.9 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 ABX13277.1 - 8.5e-07 28.6 3.9 2.8e-06 27.0 0.5 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX13277.1 - 4.9e-06 27.0 0.0 2.1e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ABX13277.1 - 3.1e-05 23.4 0.1 5.5e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 ABX13277.1 - 7.9e-05 22.2 0.0 0.00013 21.5 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 ABX13277.1 - 0.0016 18.8 0.1 0.0071 16.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 ABX13277.1 - 0.0021 18.0 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ABX13277.1 - 0.0049 16.6 0.0 0.0074 16.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ABX13277.1 - 0.0052 17.2 0.0 0.012 16.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ABX13277.1 - 0.087 13.2 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF655 PF04919.7 ABX13278.1 - 5.8e-52 176.0 0.9 6.5e-52 175.8 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.1 ABX13278.1 - 0.00028 20.8 0.0 0.001 19.1 0.0 1.9 1 1 1 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.2 ABX13278.1 - 0.0019 18.0 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif CCDC144C PF14915.1 ABX13278.1 - 0.07 12.0 1.3 0.21 10.4 0.1 1.9 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region NEL PF14496.1 ABX13278.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting 4HB_MCP_1 PF12729.2 ABX13278.1 - 1.6 8.0 7.9 12 5.1 0.6 2.2 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction RNA_pol_Rpb4 PF03874.11 ABX13279.1 - 5.8e-15 55.3 1.4 1.4e-14 54.1 1.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 RPAP3_C PF13877.1 ABX13279.1 - 0.094 12.6 0.4 0.29 11.1 0.1 1.9 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 Ribosomal_L21e PF01157.13 ABX13280.1 - 3.6e-15 55.5 1.2 4.6e-15 55.2 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L21e Radical_SAM PF04055.16 ABX13281.1 - 3.4e-13 50.0 0.1 8e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 ABX13281.1 - 7.7e-05 22.6 0.0 0.00023 21.1 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 ABX13281.1 - 0.037 14.1 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Rad51 PF08423.6 ABX13282.1 - 8e-93 310.0 0.1 1.1e-92 309.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 ABX13282.1 - 1.2e-12 47.6 0.0 2.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 ABX13282.1 - 3.8e-09 36.0 0.0 6.7e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.16 ABX13282.1 - 8.3e-09 34.9 0.0 1.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 ABX13282.1 - 9.2e-09 35.3 0.2 2.4e-08 34.0 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain ABC_tran PF00005.22 ABX13282.1 - 0.0026 18.0 0.2 0.0071 16.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 ABX13282.1 - 0.019 14.6 0.6 1.1 8.9 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase AAA_31 PF13614.1 ABX13282.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain Ribosomal_S30 PF04758.9 ABX13283.1 - 4.8e-08 32.6 5.9 1.2e-07 31.3 4.1 1.8 1 1 0 1 1 1 1 Ribosomal protein S30 MafB19-deam PF14437.1 ABX13283.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 MafB19-like deaminase Radical_SAM PF04055.16 ABX13284.1 - 1e-08 35.5 0.0 1.9e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily NAD_binding_1 PF00175.16 ABX13285.1 - 9.8e-18 64.7 0.0 1.8e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.4 ABX13285.1 - 3.2e-11 42.5 8.0 6e-11 41.6 5.5 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.19 ABX13285.1 - 1.3e-07 31.6 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 ABX13285.1 - 0.0076 16.1 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DHO_dh PF01180.16 ABX13286.1 - 4.5e-58 196.5 0.5 5.1e-58 196.3 0.4 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.12 ABX13286.1 - 2.1e-07 30.1 0.2 7.4e-05 21.7 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 ABX13286.1 - 4.5e-07 29.3 0.1 0.00079 18.7 0.0 2.5 2 0 0 2 2 2 2 Histidine biosynthesis protein NMO PF03060.10 ABX13286.1 - 2e-05 23.9 0.1 0.00049 19.3 0.0 2.1 1 1 0 2 2 2 1 Nitronate monooxygenase DUF561 PF04481.7 ABX13286.1 - 0.0003 19.8 7.7 0.00042 19.3 0.0 3.4 3 1 0 4 4 4 1 Protein of unknown function (DUF561) ThiG PF05690.9 ABX13286.1 - 0.00081 18.5 2.5 0.15 11.0 0.3 2.7 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 ABX13286.1 - 0.0011 17.9 0.3 0.0021 16.9 0.0 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain PcrB PF01884.12 ABX13286.1 - 0.016 14.4 0.3 0.98 8.6 0.0 3.0 3 0 0 3 3 3 0 PcrB family G3P_antiterm PF04309.7 ABX13286.1 - 0.058 12.4 0.2 4.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Nop PF01798.13 ABX13287.1 - 3.5e-50 169.1 0.3 6.6e-50 168.2 0.2 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 ABX13287.1 - 9.1e-21 73.4 0.0 1.9e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain Recep_L_domain PF01030.19 ABX13287.1 - 0.12 12.3 1.4 0.22 11.5 0.5 1.7 2 0 0 2 2 2 0 Receptor L domain Fibrillarin PF01269.12 ABX13288.1 - 4.2e-88 294.1 0.1 4.6e-88 293.9 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 ABX13288.1 - 0.00045 19.7 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 ABX13288.1 - 0.0022 17.5 0.0 0.0036 16.8 0.0 1.3 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4651 PF15513.1 ABX13288.1 - 0.015 14.6 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) FtsJ PF01728.14 ABX13288.1 - 0.053 13.4 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase DHHA2 PF02833.9 ABX13288.1 - 0.091 12.9 0.0 1.6 8.9 0.0 2.1 2 0 0 2 2 2 0 DHHA2 domain RNase_HII PF01351.13 ABX13289.1 - 1.7e-43 148.5 0.2 1.9e-43 148.4 0.1 1.0 1 0 0 1 1 1 1 Ribonuclease HII TRM PF02005.11 ABX13290.1 - 1e-81 274.7 0.0 1.2e-81 274.5 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Rrf2 PF02082.15 ABX13290.1 - 0.0064 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator Met_10 PF02475.11 ABX13290.1 - 0.0084 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 ABX13290.1 - 0.023 14.2 0.2 0.073 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Bromodomain PF00439.20 ABX13290.1 - 0.041 13.8 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Bromodomain MTS PF05175.9 ABX13290.1 - 0.047 13.0 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 ABX13290.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain zf-C3HC4_3 PF13920.1 ABX13290.1 - 4.9 6.8 7.3 0.34 10.6 1.4 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FtsJ PF01728.14 ABX13291.1 - 9.6e-51 172.3 0.0 1.1e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 ABX13291.1 - 5.9e-05 22.6 0.4 0.00054 19.5 0.3 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ABX13291.1 - 0.0035 17.0 0.1 0.016 14.9 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ABX13291.1 - 0.0091 16.3 0.0 0.02 15.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX13291.1 - 0.024 15.2 0.3 0.069 13.7 0.2 1.9 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 ABX13291.1 - 0.041 12.9 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Nol1_Nop2_Fmu PF01189.12 ABX13291.1 - 0.1 11.9 0.0 0.49 9.7 0.0 1.8 2 0 0 2 2 2 0 NOL1/NOP2/sun family RNA_pol_Rpc34 PF05158.7 ABX13292.1 - 0.0011 18.2 12.2 0.0011 18.2 8.4 2.4 1 1 1 2 2 2 1 RNA polymerase Rpc34 subunit MarR PF01047.17 ABX13292.1 - 0.0024 17.5 0.2 0.0047 16.5 0.1 1.4 1 0 0 1 1 1 1 MarR family Mitofilin PF09731.4 ABX13292.1 - 4.6 5.7 44.9 5.4 5.5 31.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PLRV_ORF5 PF01690.12 ABX13292.1 - 6.7 5.7 27.5 8 5.4 19.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AAA_15 PF13175.1 ABX13294.1 - 2.4e-20 73.0 7.3 2.4e-20 73.0 5.1 3.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 ABX13294.1 - 2.5e-11 44.0 11.5 2.5e-11 44.0 8.0 4.5 2 2 1 3 3 3 1 AAA domain AAA_23 PF13476.1 ABX13294.1 - 8.3e-06 26.2 8.1 8.3e-06 26.2 5.6 2.6 2 0 0 2 2 2 1 AAA domain DUF2813 PF11398.3 ABX13294.1 - 0.0008 18.5 0.4 0.38 9.7 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2813) AAA_29 PF13555.1 ABX13294.1 - 0.0021 17.5 0.3 0.0073 15.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 ABX13294.1 - 0.0039 17.4 2.4 0.0067 16.7 0.3 2.5 2 1 0 2 2 2 1 ABC transporter Glyco_hydro_42C PF08533.5 ABX13294.1 - 0.04 13.4 0.1 0.68 9.4 0.0 2.4 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain A2M_N PF01835.14 ABX13295.1 - 5.5e-22 77.8 0.2 6.3e-05 23.1 0.0 6.3 7 0 0 7 7 7 3 MG2 domain FlgD_ig PF13860.1 ABX13295.1 - 1e-05 25.1 8.0 0.026 14.2 0.2 5.7 5 1 1 6 6 6 2 FlgD Ig-like domain Cna_B PF05738.8 ABX13295.1 - 0.065 12.9 6.1 16 5.3 0.1 5.0 6 0 0 6 6 6 0 Cna protein B-type domain PPC PF04151.10 ABX13295.1 - 0.32 11.9 0.1 0.32 11.9 0.0 4.2 3 1 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Pribosyltran PF00156.22 ABX13296.1 - 7.8e-19 67.6 0.1 9.4e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 ABX13296.1 - 0.0025 17.0 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PNP_UDP_1 PF01048.15 ABX13297.1 - 2.1e-45 154.5 0.0 2.4e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily zf-met PF12874.2 ABX13299.1 - 0.061 13.5 0.4 0.14 12.4 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type TrmB PF01978.14 ABX13300.1 - 0.00044 19.8 0.0 0.0007 19.2 0.0 1.5 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Ribosomal_S25 PF03297.10 ABX13300.1 - 0.053 13.5 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 S25 ribosomal protein GvpH PF05455.6 ABX13302.1 - 0.001 18.7 0.0 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 GvpH DUF3169 PF11368.3 ABX13302.1 - 0.05 12.8 2.6 0.072 12.2 1.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) RseC_MucC PF04246.7 ABX13302.1 - 0.12 11.8 0.2 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC TP6A_N PF04406.9 ABX13303.1 - 2.2e-19 68.8 0.2 5.5e-19 67.5 0.1 1.7 2 0 0 2 2 2 1 Type IIB DNA topoisomerase Toprim PF01751.17 ABX13303.1 - 0.018 14.9 0.6 0.06 13.3 0.0 2.1 2 0 0 2 2 2 0 Toprim domain Topo-VIb_trans PF09239.6 ABX13304.1 - 8.8e-59 197.6 0.0 1.8e-58 196.6 0.0 1.5 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c PF02518.21 ABX13304.1 - 9.7e-08 31.7 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ABX13304.1 - 3.3e-07 30.0 0.0 6.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase KH_1 PF00013.24 ABX13305.1 - 7.7e-14 51.0 6.6 7.6e-07 28.6 0.3 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 ABX13305.1 - 1.2e-05 24.8 7.5 0.016 14.8 0.2 2.9 2 1 1 3 3 3 2 KH domain KH_2 PF07650.12 ABX13305.1 - 0.71 9.4 4.0 3 7.4 0.4 2.6 2 0 0 2 2 2 0 KH domain RIO1 PF01163.17 ABX13306.1 - 1.8e-54 183.9 0.0 2.4e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 ABX13306.1 - 0.00049 19.8 0.0 0.11 12.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 ABX13306.1 - 0.0099 14.9 0.0 2.3 7.2 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Trigger_N PF05697.8 ABX13306.1 - 0.016 14.9 0.1 0.041 13.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) DUF424 PF04242.8 ABX13307.1 - 5.8e-24 83.9 0.1 6.7e-24 83.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF424) eIF-5_eIF-2B PF01873.12 ABX13308.1 - 9e-27 93.2 0.0 1.1e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 ABX13308.1 - 0.0044 16.3 0.6 0.0078 15.5 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2387 PF09526.5 ABX13308.1 - 0.022 14.6 0.1 0.041 13.7 0.1 1.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.8 ABX13308.1 - 0.027 14.1 0.3 0.047 13.3 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 ABX13308.1 - 0.049 13.9 0.3 0.078 13.2 0.2 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 ABX13308.1 - 0.18 11.7 1.8 3.2 7.8 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zf-TFIIB PF13453.1 ABX13308.1 - 1.2 8.3 3.2 0.62 9.2 0.8 1.6 2 0 0 2 2 2 0 Transcription factor zinc-finger Antiterm PF03589.8 ABX13309.1 - 0.013 15.5 0.5 0.016 15.2 0.3 1.2 1 0 0 1 1 1 0 Antitermination protein HypA PF01155.14 ABX13309.1 - 0.015 14.9 0.4 0.016 14.9 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Auto_anti-p27 PF06677.7 ABX13309.1 - 0.023 14.4 1.5 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.9 ABX13309.1 - 0.039 13.9 2.1 0.11 12.4 1.5 1.7 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 ABX13309.1 - 0.045 13.5 2.9 0.14 12.0 2.0 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 ABX13309.1 - 0.054 12.7 2.1 0.14 11.4 0.4 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 ABX13309.1 - 0.058 12.9 1.6 0.32 10.5 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 ABX13309.1 - 0.06 12.6 2.3 1.2 8.4 0.2 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding DNA_ligase_ZBD PF03119.11 ABX13309.1 - 0.071 12.8 0.1 0.071 12.8 0.1 1.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-dskA_traR PF01258.12 ABX13309.1 - 0.096 12.4 2.1 5.3 6.8 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-ISL3 PF14690.1 ABX13309.1 - 0.11 12.5 3.0 2.4 8.2 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2072 PF09845.4 ABX13309.1 - 0.22 11.4 1.4 0.3 11.0 1.0 1.4 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Zn-ribbon_8 PF09723.5 ABX13309.1 - 0.85 9.6 4.0 5.8 6.9 2.8 2.0 1 1 1 2 2 2 0 Zinc ribbon domain DUF1610 PF07754.6 ABX13309.1 - 4.9 7.3 7.4 2.1 8.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zinc_ribbon_4 PF13717.1 ABX13309.1 - 5.8 6.7 6.2 41 3.9 4.3 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 ABX13309.1 - 6.3 6.4 6.4 46 3.7 4.4 2.1 1 1 0 1 1 1 0 zinc-ribbon domain UPF0118 PF01594.11 ABX13310.1 - 0.029 13.3 0.2 0.044 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 Strumpellin PF10266.4 ABX13310.1 - 0.029 11.8 0.8 0.043 11.2 0.4 1.4 1 1 1 2 2 2 0 Hereditary spastic paraplegia protein strumpellin YceG PF02618.11 ABX13310.1 - 0.053 12.5 0.5 0.064 12.2 0.4 1.1 1 0 0 1 1 1 0 YceG-like family DUF2482 PF10655.4 ABX13310.1 - 0.093 12.7 0.3 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) DUF4441 PF14536.1 ABX13310.1 - 0.35 10.8 2.7 0.71 9.8 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) DUF373 PF04123.8 ABX13311.1 - 1.9e-109 365.8 11.9 2.2e-109 365.6 8.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF373) Prenyltransf PF01255.14 ABX13312.1 - 4.4e-77 258.1 0.1 5.5e-77 257.8 0.1 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase NUDIX PF00293.23 ABX13313.1 - 2.5e-19 69.2 0.1 3.2e-19 68.9 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain OMPdecase PF00215.19 ABX13314.1 - 4.6e-28 98.1 0.0 5.7e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Adenylsucc_synt PF00709.16 ABX13316.1 - 9.9e-89 297.8 2.5 7.4e-43 146.7 0.0 3.0 1 1 2 3 3 3 3 Adenylosuccinate synthetase Annexin PF00191.15 ABX13317.1 - 0.045 13.6 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Annexin CofC PF01983.11 ABX13317.1 - 0.064 12.2 0.1 0.098 11.6 0.1 1.3 1 0 0 1 1 1 0 Guanylyl transferase CofC like Iron_traffic PF04362.9 ABX13318.1 - 4.1e-08 32.5 3.3 7.2e-08 31.7 2.3 1.6 1 1 0 1 1 1 1 Bacterial Fe(2+) trafficking zinc_ribbon_2 PF13240.1 ABX13318.1 - 0.018 14.4 3.7 0.065 12.7 2.6 1.9 1 1 0 1 1 1 0 zinc-ribbon domain DUF3797 PF12677.2 ABX13318.1 - 9.6 5.9 7.4 17 5.0 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zinc_ribbon_4 PF13717.1 ABX13320.1 - 0.038 13.6 5.2 0.53 10.0 3.6 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 ABX13320.1 - 0.043 13.3 5.2 0.6 9.7 3.6 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Mu-like_Com PF10122.4 ABX13320.1 - 0.048 12.7 0.3 0.56 9.3 0.1 2.1 2 0 0 2 2 2 0 Mu-like prophage protein Com Lar_restr_allev PF14354.1 ABX13320.1 - 0.075 13.3 1.9 0.55 10.5 1.3 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1 PF03811.8 ABX13320.1 - 0.078 12.4 0.4 0.91 9.0 0.1 2.1 2 0 0 2 2 2 0 InsA N-terminal domain zf-ribbon_3 PF13248.1 ABX13320.1 - 0.21 10.8 4.0 0.45 9.7 2.8 1.6 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_S27e PF01667.12 ABX13320.1 - 0.24 10.9 3.8 0.62 9.6 2.6 1.7 1 1 0 1 1 1 0 Ribosomal protein S27 DUF329 PF03884.9 ABX13320.1 - 0.34 10.4 2.3 2.9 7.5 2.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF329) TFIIS_C PF01096.13 ABX13320.1 - 0.55 9.8 2.9 6.7 6.4 0.5 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PIRT PF15099.1 ABX13321.1 - 0.017 14.3 3.1 0.023 13.8 0.3 2.2 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family DUF1146 PF06612.6 ABX13321.1 - 0.64 9.9 0.1 0.64 9.9 0.0 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF1146) HTH_45 PF14947.1 ABX13322.1 - 1.3e-12 47.2 0.1 1.8e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.2 ABX13322.1 - 3.8e-08 32.8 0.0 4.9e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 ABX13322.1 - 2.3e-05 23.9 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.1 ABX13322.1 - 2.5e-05 24.4 0.1 3.2e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.5 ABX13322.1 - 6.3e-05 22.4 0.0 8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.17 ABX13322.1 - 0.00028 20.5 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.1 ABX13322.1 - 0.0005 19.4 0.1 0.00083 18.6 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.1 ABX13322.1 - 0.00063 19.7 0.0 0.00098 19.1 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain Mrr_N PF14338.1 ABX13322.1 - 0.0011 18.9 0.0 0.0016 18.4 0.0 1.3 1 1 0 1 1 1 1 Mrr N-terminal domain RQC PF09382.5 ABX13322.1 - 0.0025 17.4 0.0 0.0028 17.3 0.0 1.1 1 0 0 1 1 1 1 RQC domain HTH_20 PF12840.2 ABX13322.1 - 0.0027 17.4 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain RPA_C PF08784.6 ABX13322.1 - 0.0054 17.1 0.0 0.008 16.5 0.0 1.2 1 0 0 1 1 1 1 Replication protein A C terminal RP-C PF03428.8 ABX13322.1 - 0.0067 15.8 0.0 0.007 15.8 0.0 1.1 1 0 0 1 1 1 1 Replication protein C N-terminal domain DUF4194 PF13835.1 ABX13322.1 - 0.013 14.9 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) Rrf2 PF02082.15 ABX13322.1 - 0.019 15.0 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_Crp_2 PF13545.1 ABX13322.1 - 0.023 14.4 0.3 0.066 13.0 0.1 1.7 1 1 0 2 2 2 0 Crp-like helix-turn-helix domain PadR PF03551.9 ABX13322.1 - 0.034 13.8 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4364 PF14277.1 ABX13322.1 - 0.036 13.6 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) RNA_pol_Rpc34 PF05158.7 ABX13322.1 - 0.036 13.2 0.0 0.036 13.2 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit HTH_5 PF01022.15 ABX13322.1 - 0.049 13.3 0.1 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF2250 PF10007.4 ABX13322.1 - 0.058 13.3 0.1 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Linker_histone PF00538.14 ABX13322.1 - 0.081 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 linker histone H1 and H5 family Sua5_yciO_yrdC PF01300.13 ABX13323.1 - 5.3e-49 165.8 0.0 6e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination THUMP PF02926.12 ABX13324.1 - 1.4e-14 54.1 2.7 1.8e-14 53.8 1.9 1.1 1 0 0 1 1 1 1 THUMP domain ThiS PF02597.15 ABX13325.1 - 3.9e-10 39.9 0.2 1.7e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 ThiS family CGI-121 PF08617.5 ABX13325.1 - 3.2e-09 36.6 5.4 4.9e-09 36.0 3.8 1.3 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Urm1 PF09138.6 ABX13325.1 - 0.00013 22.0 2.1 0.00021 21.3 0.4 2.2 2 1 0 2 2 2 1 Urm1 (Ubiquitin related modifier) HPHLAWLY PF14925.1 ABX13325.1 - 0.0028 15.7 1.3 0.0035 15.4 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF436 PF04260.7 ABX13325.1 - 0.05 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF436) Ribosomal_S17e PF00833.13 ABX13326.1 - 1e-27 96.3 1.9 1.1e-27 96.1 1.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 DUF2360 PF10152.4 ABX13326.1 - 0.99 9.6 8.9 1.2 9.4 6.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PGA2 PF07543.7 ABX13326.1 - 1.1 9.0 6.4 1.7 8.4 4.5 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2052 PF09747.4 ABX13326.1 - 2.4 8.0 8.8 2.6 7.9 6.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) MCPVI PF02993.9 ABX13326.1 - 2.8 8.0 8.7 3 7.9 6.0 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DUF3275 PF11679.3 ABX13326.1 - 8.3 5.9 6.8 11 5.6 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) TatD_DNase PF01026.16 ABX13327.1 - 1.2e-45 155.7 0.0 1.3e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase CBFD_NFYB_HMF PF00808.18 ABX13328.1 - 2.4e-13 49.9 0.1 2.7e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ABX13328.1 - 3.9e-07 30.1 0.1 4.8e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 ABX13328.1 - 6.3e-05 23.0 0.0 7.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S TFIID-31kDa PF02291.10 ABX13328.1 - 0.0017 18.1 0.0 0.0018 18.0 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 ABX13328.1 - 0.018 14.7 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 ABX13328.1 - 0.062 13.5 0.0 0.072 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TAF PF02969.12 ABX13328.1 - 0.075 12.9 0.4 0.09 12.7 0.2 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF1065 PF06358.6 ABX13330.1 - 0.03 14.0 0.1 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) PD40 PF07676.7 ABX13332.1 - 2.9e-12 45.9 0.6 0.063 12.9 0.0 5.8 5 0 0 5 5 5 4 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ABX13332.1 - 7.8e-07 27.9 0.3 0.0003 19.5 0.0 3.8 3 1 1 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region A2M_N PF01835.14 ABX13332.1 - 3.6e-06 27.1 0.0 0.0025 18.0 0.0 2.5 2 0 0 2 2 2 2 MG2 domain DUF3244 PF11589.3 ABX13332.1 - 0.012 15.3 0.1 0.033 13.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) Kelch_4 PF13418.1 ABX13333.1 - 0.11 12.2 0.1 0.3 10.8 0.1 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain Redoxin PF08534.5 ABX13334.1 - 3.1e-10 39.7 0.0 3.9e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 ABX13334.1 - 9.5e-09 35.0 0.0 0.00032 20.3 0.0 2.1 2 0 0 2 2 2 2 AhpC/TSA family DUF899 PF05988.7 ABX13334.1 - 0.0052 16.2 0.0 0.0056 16.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Glyoxalase_2 PF12681.2 ABX13335.1 - 4.5e-12 46.5 0.0 5.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 ABX13335.1 - 1.8e-10 40.9 0.0 2.2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 ABX13335.1 - 0.0035 17.3 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HATPase_c PF02518.21 ABX13336.1 - 2e-19 69.3 0.1 5.4e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ABX13336.1 - 9e-13 48.0 0.1 1.8e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 ABX13336.1 - 8e-05 22.2 1.6 0.00016 21.2 0.3 2.1 2 0 0 2 2 2 1 GHKL domain Cache_3 PF14827.1 ABX13336.1 - 0.0098 15.7 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Sensory domain of two-component sensor kinase DUF3139 PF11337.3 ABX13336.1 - 0.085 13.1 5.2 0.69 10.2 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Baculo_11_kDa PF06143.6 ABX13336.1 - 0.26 10.6 3.6 1.1 8.6 0.2 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family TarH PF02203.10 ABX13336.1 - 1 9.1 6.5 11 5.8 1.4 2.5 2 1 0 2 2 2 0 Tar ligand binding domain homologue SMP_2 PF10144.4 ABX13336.1 - 2 7.4 6.8 1.9 7.5 0.2 2.7 2 1 1 3 3 3 0 Bacterial virulence factor haemolysin ODV-E18 PF10717.4 ABX13338.1 - 1.3 8.4 4.0 1.9 7.9 2.7 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Copper-bind PF00127.15 ABX13339.1 - 2.4e-07 30.9 0.0 8.9e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 ABX13339.1 - 1e-05 25.3 0.0 3.1e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Cupredoxin-like domain AIPR PF10592.4 ABX13340.1 - 1.5e-66 224.8 7.5 1.5e-66 224.8 5.2 2.4 3 0 0 3 3 3 1 AIPR protein HTH_45 PF14947.1 ABX13342.1 - 2.1e-17 62.6 0.1 2.5e-17 62.4 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix Mrr_N PF14338.1 ABX13342.1 - 0.00045 20.2 0.0 0.00057 19.9 0.0 1.2 1 0 0 1 1 1 1 Mrr N-terminal domain HTH_34 PF13601.1 ABX13342.1 - 0.0011 18.9 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.15 ABX13342.1 - 0.002 18.1 0.1 0.0036 17.4 0.0 1.4 2 0 0 2 2 2 1 Transcriptional regulator RNA_pol_Rpc34 PF05158.7 ABX13342.1 - 0.0039 16.4 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Ribosomal_S19e PF01090.14 ABX13342.1 - 0.0067 15.8 0.0 0.007 15.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e RPA_C PF08784.6 ABX13342.1 - 0.008 16.5 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 Replication protein A C terminal MarR PF01047.17 ABX13342.1 - 0.0088 15.7 0.1 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 MarR family DUF4364 PF14277.1 ABX13342.1 - 0.014 14.9 0.0 0.019 14.5 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4364) HTH_27 PF13463.1 ABX13342.1 - 0.03 14.6 0.0 0.042 14.1 0.0 1.3 1 1 0 1 1 1 0 Winged helix DNA-binding domain PadR PF03551.9 ABX13342.1 - 0.032 13.9 0.1 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family TrmB PF01978.14 ABX13342.1 - 0.056 13.1 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 ABX13342.1 - 0.081 12.7 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC PGM_PMM_I PF02878.11 ABX13343.1 - 4.2e-23 81.3 0.0 3e-22 78.6 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 ABX13343.1 - 3.3e-15 56.0 0.0 7.7e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 ABX13343.1 - 5.5e-15 55.5 0.0 1.3e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 ABX13343.1 - 3.2e-08 33.4 0.1 8.7e-08 32.0 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Glyco_transf_41 PF13844.1 ABX13343.1 - 0.092 10.7 0.2 0.14 10.0 0.2 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 PD40 PF07676.7 ABX13343.1 - 0.11 12.2 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat AIRS PF00586.19 ABX13344.1 - 3.8e-14 52.7 0.0 9.7e-14 51.3 0.0 1.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.17 ABX13344.1 - 6.9e-06 26.1 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain DUF4034 PF13226.1 ABX13345.1 - 0.0015 17.6 0.1 0.0017 17.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4034) Ribosomal_S11 PF00411.14 ABX13346.1 - 1.1e-29 102.7 0.9 1.3e-29 102.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Mu-transpos_C PF09299.6 ABX13346.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Mu transposase, C-terminal dsDNA_bind PF01984.15 ABX13348.1 - 3.4e-07 30.2 1.3 4.7e-07 29.7 0.9 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.4 ABX13348.1 - 0.013 15.6 0.9 0.024 14.7 0.7 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region RtcB PF01139.12 ABX13349.1 - 1.5e-150 501.8 0.2 1.7e-150 501.7 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB DUF3492 PF11997.3 ABX13349.1 - 0.015 14.8 0.1 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Complex1_LYR PF05347.10 ABX13349.1 - 0.032 14.0 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF1876 PF08962.6 ABX13350.1 - 0.051 13.3 0.5 0.062 13.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) KBP_C PF12309.3 ABX13350.1 - 0.14 11.1 4.5 0.14 11.0 3.1 1.0 1 0 0 1 1 1 0 KIF-1 binding protein C terminal DUF2215 PF10225.4 ABX13350.1 - 0.28 10.6 2.5 0.31 10.4 1.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Rtf2 PF04641.7 ABX13350.1 - 1.5 7.9 10.2 1.6 7.8 7.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Borrelia_P83 PF05262.6 ABX13350.1 - 5.5 5.1 14.2 6.3 4.9 9.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Lyase_1 PF00206.15 ABX13351.1 - 1.1e-48 165.9 1.4 1.5e-48 165.5 0.9 1.1 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 ABX13351.1 - 1.2e-18 66.8 0.0 3e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DM13 PF10517.4 ABX13352.1 - 2.5e-26 92.1 0.4 6.7e-26 90.7 0.1 1.8 2 0 0 2 2 2 1 Electron transfer DM13 A2M_N PF01835.14 ABX13352.1 - 1.2e-05 25.4 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 MG2 domain DUF4469 PF14734.1 ABX13352.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold DUF1569 PF07606.6 ABX13352.1 - 0.082 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) DUF4625 PF15418.1 ABX13352.1 - 0.1 12.7 0.1 0.65 10.1 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4625) Methyltransf_31 PF13847.1 ABX13353.1 - 7.6e-36 122.9 0.1 1.3e-35 122.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ABX13353.1 - 8.7e-21 74.2 0.0 1.5e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ABX13353.1 - 8.9e-21 74.2 0.0 2.3e-20 72.9 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ABX13353.1 - 4.7e-20 71.8 0.0 1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX13353.1 - 1.9e-19 70.3 0.0 5.2e-19 68.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ABX13353.1 - 5.7e-15 55.5 0.0 1.3e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ABX13353.1 - 2.9e-11 42.9 0.1 1.1e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ABX13353.1 - 9.3e-11 41.7 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ABX13353.1 - 1.3e-10 40.8 0.0 2.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 ABX13353.1 - 1.9e-10 40.4 0.1 3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 ABX13353.1 - 1e-08 34.9 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 ABX13353.1 - 1.1e-08 34.3 0.0 3.3e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase DREV PF05219.7 ABX13353.1 - 6e-06 25.3 0.0 3.3e-05 22.9 0.0 1.9 1 1 1 2 2 2 1 DREV methyltransferase Methyltransf_32 PF13679.1 ABX13353.1 - 6.9e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 ABX13353.1 - 1.1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.6 ABX13353.1 - 1.1e-05 24.8 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 ABX13353.1 - 1.4e-05 24.3 0.0 2.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 ABX13353.1 - 2.4e-05 23.5 0.0 3.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_2 PF00891.13 ABX13353.1 - 2.6e-05 23.5 0.0 4.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase GCD14 PF08704.5 ABX13353.1 - 3.7e-05 23.3 0.0 5.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit CheR PF01739.13 ABX13353.1 - 0.00012 21.4 0.0 0.11 11.7 0.1 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_20 PF12147.3 ABX13353.1 - 0.0011 17.8 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 ABX13353.1 - 0.0014 17.8 0.1 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB UPF0020 PF01170.13 ABX13353.1 - 0.0023 17.5 0.0 0.0052 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.5 ABX13353.1 - 0.0051 16.3 0.1 0.92 9.0 0.0 2.3 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase DUF938 PF06080.7 ABX13353.1 - 0.013 14.9 0.0 0.023 14.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) TPMT PF05724.6 ABX13353.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_24 PF13578.1 ABX13353.1 - 0.024 15.4 0.0 0.066 14.0 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 ABX13353.1 - 0.027 13.1 0.0 0.045 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Rrf2 PF02082.15 ABX13353.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator HTH_45 PF14947.1 ABX13353.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix YxiJ PF14176.1 ABX13355.1 - 0.024 14.7 0.3 0.054 13.6 0.1 1.6 1 1 1 2 2 2 0 YxiJ-like protein DUF4064 PF13273.1 ABX13355.1 - 0.03 14.4 0.2 0.036 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) SurA_N_2 PF13623.1 ABX13355.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 SurA N-terminal domain PPO1_DWL PF12142.3 ABX13355.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Trypan_PARP PF05887.6 ABX13357.1 - 0.13 12.0 1.2 0.21 11.4 0.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glyoxalase_2 PF12681.2 ABX13359.1 - 1.1e-11 45.2 0.0 1.4e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 ABX13359.1 - 0.001 19.0 0.1 0.006 16.5 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2296 PF10058.4 ABX13360.1 - 0.087 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Asn_synthase PF00733.16 ABX13362.1 - 5.3e-29 101.4 0.0 9.1e-29 100.7 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 ABX13362.1 - 1.5e-05 24.0 0.2 4.8e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 NAD synthase QueC PF06508.8 ABX13362.1 - 0.0001 21.6 0.0 0.0002 20.7 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC DUF2683 PF10884.3 ABX13362.1 - 0.01 15.7 0.1 0.026 14.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) ATP_bind_3 PF01171.15 ABX13362.1 - 0.033 13.6 0.0 0.096 12.1 0.0 1.9 2 1 0 2 2 2 0 PP-loop family SNase PF00565.12 ABX13363.1 - 2.7e-10 40.4 0.0 5.2e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Excalibur PF05901.6 ABX13363.1 - 0.0052 17.0 1.9 0.0052 17.0 1.3 2.1 2 0 0 2 2 2 1 Excalibur calcium-binding domain Ly49 PF08391.5 ABX13363.1 - 0.057 13.5 0.3 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Pterin_4a PF01329.14 ABX13364.1 - 6.4e-31 105.9 0.0 6.9e-31 105.8 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.3 ABX13364.1 - 0.051 13.4 0.0 0.13 12.0 0.0 1.7 1 1 1 2 2 2 0 Translation-initiation factor 2 PTPS PF01242.14 ABX13365.1 - 1.5e-19 69.8 0.6 9.7e-19 67.2 0.0 2.1 2 0 0 2 2 2 1 6-pyruvoyl tetrahydropterin synthase Cupin_3 PF05899.7 ABX13365.1 - 0.13 11.6 0.0 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Sigma70_r4_2 PF08281.7 ABX13366.1 - 0.0012 18.2 0.0 0.0038 16.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 UPF0122 PF04297.9 ABX13366.1 - 0.002 18.1 0.1 0.0047 16.9 0.1 1.7 1 1 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_23 PF13384.1 ABX13366.1 - 0.0034 16.9 0.0 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.11 ABX13366.1 - 0.034 13.4 0.0 0.082 12.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3399 PF11879.3 ABX13366.1 - 0.055 13.7 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) RPN7 PF10602.4 ABX13366.1 - 0.14 11.5 2.6 0.85 8.9 0.2 2.2 2 0 0 2 2 2 0 26S proteasome subunit RPN7 dCMP_cyt_deam_1 PF00383.17 ABX13367.1 - 3.9e-15 55.3 0.3 4.5e-15 55.1 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region YwqJ-deaminase PF14431.1 ABX13367.1 - 0.091 12.6 0.6 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 YwqJ-like deaminase LmjF365940-deam PF14421.1 ABX13367.1 - 0.15 11.4 1.1 0.94 8.8 0.1 1.9 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases AAA_5 PF07728.9 ABX13368.1 - 9.4e-05 22.1 0.1 0.00039 20.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ABX13368.1 - 0.00087 19.4 0.0 0.0078 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.1 ABX13368.1 - 0.0019 18.4 0.0 0.06 13.6 0.0 3.0 2 1 1 3 3 3 1 HEAT repeats AAA_16 PF13191.1 ABX13368.1 - 0.004 17.1 0.0 0.015 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 ABX13368.1 - 0.011 15.3 0.0 0.032 13.8 0.0 1.8 1 0 0 1 1 1 0 NACHT domain DUF2161 PF09929.4 ABX13368.1 - 0.013 15.4 0.3 0.045 13.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2161) DUF87 PF01935.12 ABX13368.1 - 0.071 12.9 0.3 0.071 12.9 0.2 3.8 4 0 0 4 4 4 0 Domain of unknown function DUF87 AAA_18 PF13238.1 ABX13368.1 - 0.075 13.3 0.3 0.075 13.3 0.2 3.6 3 0 0 3 3 3 0 AAA domain DUF2693 PF10902.3 ABX13368.1 - 0.14 12.1 1.9 0.3 10.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2693) ApoLp-III PF07464.6 ABX13368.1 - 0.53 10.2 17.6 2.5 8.1 0.4 3.9 4 1 1 5 5 5 0 Apolipophorin-III precursor (apoLp-III) DNA_methylase PF00145.12 ABX13369.1 - 2.7e-66 223.9 0.8 3.2e-66 223.7 0.5 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Cons_hypoth95 PF03602.10 ABX13369.1 - 4.1e-05 23.0 0.0 7.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 ABX13369.1 - 0.00034 20.1 1.0 0.00053 19.5 0.1 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 ABX13369.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Imm42 PF15601.1 ABX13369.1 - 0.018 14.4 0.0 0.045 13.1 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 42 PrmA PF06325.8 ABX13369.1 - 0.045 12.8 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Curto_V2 PF07325.6 ABX13369.1 - 0.048 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Curtovirus V2 protein SopA PF13981.1 ABX13370.1 - 0.061 13.3 1.3 1 9.4 0.2 2.4 2 0 0 2 2 2 0 SopA-like central domain CRISPR_Cas2 PF09827.4 ABX13370.1 - 0.083 13.0 0.5 0.48 10.5 0.1 2.2 2 0 0 2 2 2 0 CRISPR associated protein Cas2 RNA_helicase PF00910.17 ABX13371.1 - 0.0004 20.5 0.3 0.0085 16.2 0.0 2.9 3 0 0 3 3 3 1 RNA helicase AAA_5 PF07728.9 ABX13371.1 - 0.055 13.1 0.0 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ABX13371.1 - 0.058 13.5 0.1 1 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 ABX13371.1 - 0.07 13.0 3.6 0.12 12.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.1 ABX13371.1 - 0.089 12.8 0.1 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain SRCR_2 PF15494.1 ABX13371.1 - 0.1 12.8 0.1 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain tRNA-synt_1 PF00133.17 ABX13373.1 - 8.2e-108 360.9 0.1 5.3e-107 358.2 0.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 ABX13373.1 - 2.1e-33 115.2 2.7 2.1e-33 115.2 1.9 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 ABX13373.1 - 1.9e-22 79.5 1.0 2.5e-10 39.6 0.0 3.6 2 2 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 ABX13373.1 - 1e-05 24.9 0.9 0.0032 16.7 0.0 3.3 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 SNO PF01174.14 ABX13374.1 - 1.7e-47 161.5 0.2 1.9e-47 161.3 0.1 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase PF00117.23 ABX13374.1 - 2.2e-14 53.3 0.0 4.2e-14 52.4 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 ABX13374.1 - 1.4e-12 47.4 0.0 2.5e-12 46.6 0.0 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.12 ABX13374.1 - 8.3e-07 28.8 0.1 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 Peptidase_C26 PF07722.8 ABX13374.1 - 1.5e-05 24.5 0.0 0.00012 21.6 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 ABX13374.1 - 2e-05 24.0 0.0 4.9e-05 22.8 0.0 1.6 1 1 0 2 2 2 1 DJ-1/PfpI family BPL_N PF09825.4 ABX13374.1 - 0.0019 17.0 0.0 0.093 11.4 0.0 2.4 2 1 0 2 2 2 1 Biotin-protein ligase, N terminal DUF4066 PF13278.1 ABX13374.1 - 0.066 12.4 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Putative amidotransferase SOR_SNZ PF01680.12 ABX13375.1 - 1.1e-88 296.3 5.2 1.7e-88 295.6 3.6 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 ABX13375.1 - 7e-08 31.8 3.5 3.9e-06 26.1 0.2 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 ABX13375.1 - 0.00016 20.9 4.1 0.012 14.7 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 ABX13375.1 - 0.00033 20.0 1.0 0.055 12.7 0.1 3.1 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 ABX13375.1 - 0.00064 18.8 0.0 0.0072 15.4 0.0 2.3 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase Dus PF01207.12 ABX13375.1 - 0.00069 18.5 0.5 0.73 8.6 0.1 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) OMPdecase PF00215.19 ABX13375.1 - 0.0074 15.7 1.9 0.43 9.9 0.0 2.5 2 1 1 3 3 3 2 Orotidine 5'-phosphate decarboxylase / HUMPS family NanE PF04131.9 ABX13375.1 - 0.043 12.7 2.9 0.43 9.5 0.0 3.0 2 2 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase DSX_dimer PF08828.5 ABX13375.1 - 0.052 13.0 0.0 4.1 7.0 0.0 2.7 2 0 0 2 2 2 0 Doublesex dimerisation domain CBS PF00571.23 ABX13377.1 - 3.9e-41 138.5 6.0 3.3e-10 39.5 0.2 4.3 4 0 0 4 4 4 4 CBS domain Aconitase PF00330.15 ABX13378.1 - 1.1e-151 505.5 0.1 8e-151 502.6 0.1 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ABX13378.1 - 8.6e-39 132.6 0.1 2.6e-38 131.0 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF521 PF04412.8 ABX13378.1 - 0.016 13.7 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) NMT1_2 PF13379.1 ABX13379.1 - 0.1 11.9 0.1 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family AsnC_trans_reg PF01037.16 ABX13381.1 - 4.2e-11 42.4 0.0 4.8e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 AsnC family EVE PF01878.13 ABX13382.1 - 2.7e-39 134.4 0.8 3.1e-39 134.2 0.5 1.0 1 0 0 1 1 1 1 EVE domain DUF1175 PF06672.6 ABX13382.1 - 0.019 14.3 0.1 0.067 12.5 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) Neurensin PF14927.1 ABX13383.1 - 9.5e-05 21.8 0.2 0.00011 21.5 0.2 1.0 1 0 0 1 1 1 1 Neurensin DUF308 PF03729.8 ABX13383.1 - 0.00065 19.6 5.1 0.25 11.3 0.1 2.1 2 0 0 2 2 2 2 Short repeat of unknown function (DUF308) SdpI PF13630.1 ABX13383.1 - 0.09 12.4 2.0 1.6 8.5 0.4 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF3784 PF12650.2 ABX13383.1 - 0.095 12.6 1.4 7 6.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3040 PF11239.3 ABX13383.1 - 0.11 12.6 0.1 9.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF1182 PF06681.8 ABX13383.1 - 0.13 11.5 0.7 0.14 11.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) FtsX PF02687.16 ABX13383.1 - 0.13 11.9 2.5 0.18 11.5 1.8 1.2 1 0 0 1 1 1 0 FtsX-like permease family DUF3185 PF11381.3 ABX13383.1 - 0.18 11.6 0.4 0.18 11.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Pox_A14 PF05767.7 ABX13383.1 - 0.2 11.6 1.4 2.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF3953 PF13129.1 ABX13383.1 - 0.95 9.1 12.4 0.72 9.5 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) 7TM_GPCR_Srh PF10318.4 ABX13383.1 - 1.1 8.0 3.7 2.9 6.6 0.1 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF4064 PF13273.1 ABX13383.1 - 3 7.9 9.8 8.2 6.6 6.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) B5 PF03484.10 ABX13384.1 - 1.2e-20 73.0 0.0 1.2e-15 57.0 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetase B5 domain B3_4 PF03483.12 ABX13384.1 - 1e-13 51.1 0.7 2.1e-13 50.1 0.3 1.6 2 0 0 2 2 2 1 B3/4 domain DUF2218 PF09981.4 ABX13384.1 - 0.14 12.3 0.0 0.46 10.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) tRNA-synt_2d PF01409.15 ABX13385.1 - 5e-85 284.6 0.0 6.4e-85 284.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 ABX13385.1 - 1.3e-05 24.1 0.3 0.00063 18.6 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 ABX13385.1 - 0.00043 19.9 0.2 0.00089 18.8 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HTH_9 PF08221.6 ABX13385.1 - 0.022 14.6 0.0 0.054 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 ABX13385.1 - 0.098 12.1 1.7 0.33 10.4 0.0 2.3 2 0 0 2 2 2 0 TFIIE alpha subunit tRNA-synt_1b PF00579.20 ABX13386.1 - 1e-30 106.8 0.0 1.7e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.13 ABX13386.1 - 0.0042 15.8 0.0 0.084 11.5 0.0 2.6 2 1 1 3 3 3 1 tRNA synthetases class I (K) DUF970 PF06153.6 ABX13387.1 - 0.003 17.5 0.1 0.004 17.1 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF970) HDOD PF08668.7 ABX13387.1 - 0.036 13.3 0.0 0.042 13.1 0.0 1.0 1 0 0 1 1 1 0 HDOD domain zf-UBR PF02207.15 ABX13388.1 - 0.0044 16.7 14.2 0.057 13.1 0.3 3.3 4 0 0 4 4 4 2 Putative zinc finger in N-recognin (UBR box) Lar_restr_allev PF14354.1 ABX13388.1 - 0.13 12.5 15.8 4.3 7.7 1.2 5.4 2 2 2 4 4 4 0 Restriction alleviation protein Lar DZR PF12773.2 ABX13388.1 - 0.18 11.6 19.2 0.42 10.4 2.4 3.8 3 1 0 3 3 3 0 Double zinc ribbon zinc_ribbon_6 PF14599.1 ABX13388.1 - 0.52 10.1 22.8 2.8 7.7 3.5 5.1 4 2 2 6 6 6 0 Zinc-ribbon Molybdop_Fe4S4 PF04879.11 ABX13388.1 - 0.64 9.8 12.4 0.69 9.7 0.4 2.9 3 0 0 3 3 3 0 Molybdopterin oxidoreductase Fe4S4 domain LIM PF00412.17 ABX13388.1 - 0.69 10.0 13.3 2.9 8.0 1.6 3.1 3 0 0 3 3 3 0 LIM domain Elf1 PF05129.8 ABX13388.1 - 1.1 9.0 11.5 3.5 7.3 0.3 4.0 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like CTP_transf_2 PF01467.21 ABX13390.1 - 2.9e-14 53.4 0.0 3.7e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 ABX13390.1 - 0.0018 17.9 0.0 0.0047 16.5 0.0 1.7 2 0 0 2 2 2 1 FAD synthetase AhpC-TSA PF00578.16 ABX13392.1 - 4.3e-20 71.6 0.2 5.5e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ABX13392.1 - 4.3e-14 52.2 0.1 5.3e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 ABX13392.1 - 2.9e-07 30.5 0.1 4.8e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 ABX13392.1 - 2.9e-07 30.6 0.3 4.1e-07 30.1 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 ABX13392.1 - 0.0039 16.9 0.4 0.18 11.6 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin domain Thioredoxin PF00085.15 ABX13392.1 - 0.062 12.9 0.6 2.1 8.0 0.1 2.2 1 1 1 2 2 2 0 Thioredoxin CAP59_mtransfer PF11735.3 ABX13392.1 - 0.1 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Glyco_tran_WbsX PF14307.1 ABX13392.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase WbsX B12-binding_2 PF02607.12 ABX13393.1 - 0.00011 22.1 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain HTH_24 PF13412.1 ABX13393.1 - 0.0017 17.7 0.1 0.0037 16.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GntR PF00392.16 ABX13393.1 - 0.015 14.7 1.2 0.92 8.9 0.1 3.1 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family HTH_11 PF08279.7 ABX13393.1 - 0.018 14.6 0.5 0.049 13.2 0.0 1.9 2 0 0 2 2 2 0 HTH domain HTH_23 PF13384.1 ABX13393.1 - 0.038 13.6 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_IclR PF09339.5 ABX13393.1 - 0.071 12.7 0.0 0.47 10.0 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF2433 PF10360.4 ABX13393.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) TcdA_TcdB PF12919.2 ABX13394.1 - 0.022 13.2 0.5 0.026 13.0 0.4 1.0 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain LOH1CR12 PF10158.4 ABX13394.1 - 0.025 14.3 0.2 0.22 11.3 0.1 2.0 1 1 1 2 2 2 0 Tumour suppressor protein zf-Mss51 PF13824.1 ABX13394.1 - 0.029 14.2 0.1 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF217 PF02697.9 ABX13394.1 - 0.13 12.5 1.6 2.4 8.4 1.1 2.5 1 1 0 1 1 1 0 Uncharacterized ACR, COG1753 MethyltransfD12 PF02086.10 ABX13395.1 - 3.6e-65 220.0 1.4 4e-65 219.8 1.0 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_26 PF13659.1 ABX13395.1 - 0.00019 21.4 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF2089 PF09862.4 ABX13395.1 - 0.00067 19.4 0.1 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) Cons_hypoth95 PF03602.10 ABX13395.1 - 0.028 13.8 0.0 0.074 12.4 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Pico_P2A PF00947.14 ABX13395.1 - 0.071 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Picornavirus core protein 2A DNA_photolyase PF00875.13 ABX13395.1 - 0.11 12.2 0.0 0.97 9.1 0.0 2.0 2 0 0 2 2 2 0 DNA photolyase Archaeal_AmoA PF12942.2 ABX13396.1 - 1.6e-104 347.4 10.4 1.9e-104 347.2 7.2 1.0 1 0 0 1 1 1 1 Archaeal ammonia monooxygenase subunit A (AmoA) Bax1-I PF01027.15 ABX13397.1 - 0.039 13.5 5.1 0.041 13.4 3.6 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 TctB PF07331.6 ABX13397.1 - 0.12 12.0 5.9 0.15 11.6 4.1 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family ABC2_membrane_5 PF13346.1 ABX13397.1 - 0.76 9.0 5.8 1 8.6 4.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1212 PF06738.7 ABX13397.1 - 8.4 5.8 7.5 22 4.4 4.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1212) AmoC PF04896.7 ABX13398.1 - 4.2e-15 55.4 4.7 5.2e-15 55.1 3.3 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C Monooxygenase_B PF04744.7 ABX13399.1 - 1e-06 27.7 0.1 2.4e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Monooxygenase subunit B protein DNA_primase_S PF01896.14 ABX13400.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.3 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit FixQ PF05545.6 ABX13402.1 - 9.3 5.9 9.0 26 4.5 6.2 1.9 1 1 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF1469 PF07332.6 ABX13403.1 - 0.13 11.9 0.6 0.13 11.9 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) Folate_carrier PF01770.13 ABX13403.1 - 0.59 8.5 2.0 4.9 5.5 1.4 1.9 1 1 0 1 1 1 0 Reduced folate carrier Syndecan PF01034.15 ABX13403.1 - 3.6 7.2 6.4 3.3 7.4 0.7 2.5 3 0 0 3 3 3 0 Syndecan domain Ribosomal_S13_N PF08069.7 ABX13404.1 - 3.5e-26 90.7 0.3 7.1e-26 89.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 ABX13404.1 - 1.2e-16 60.2 0.3 2.1e-16 59.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 Nnf1 PF03980.9 ABX13404.1 - 0.012 15.5 0.3 0.022 14.7 0.2 1.4 1 0 0 1 1 1 0 Nnf1 DHHA1 PF02272.14 ABX13405.1 - 1.3e-10 40.8 0.2 7e-10 38.4 0.2 2.4 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.15 ABX13405.1 - 1.7e-08 34.2 0.1 2.9e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 DHH family Pcc1 PF09341.5 ABX13406.1 - 1.3e-05 25.1 0.0 1.5e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Ribosomal_L12 PF00542.14 ABX13406.1 - 0.084 12.8 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain tRNA-synt_2b PF00587.20 ABX13407.1 - 9.2e-35 119.7 0.2 1.6e-34 118.9 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 ABX13407.1 - 8.7e-26 90.0 6.6 1.7e-25 89.1 4.6 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Pox_G5 PF04599.7 ABX13407.1 - 0.05 12.3 3.1 0.087 11.4 2.1 1.3 1 0 0 1 1 1 0 Poxvirus G5 protein APG6 PF04111.7 ABX13407.1 - 0.12 11.3 6.0 1.5 7.7 1.7 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Rb_C PF08934.5 ABX13407.1 - 0.28 10.7 2.8 0.7 9.5 0.0 2.6 2 1 0 2 2 2 0 Rb C-terminal domain M PF02370.11 ABX13407.1 - 6.4 7.5 8.1 10 6.8 1.2 3.4 2 1 1 3 3 3 0 M protein repeat Ribosomal_S3Ae PF01015.13 ABX13408.1 - 9.8e-67 224.0 4.0 1.1e-66 223.8 2.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF4468 PF14730.1 ABX13408.1 - 0.059 13.0 0.2 0.19 11.4 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold RNA_binding PF01877.12 ABX13409.1 - 2e-27 95.5 4.9 2.4e-27 95.3 3.4 1.1 1 0 0 1 1 1 1 RNA binding HD_3 PF13023.1 ABX13409.1 - 0.0036 17.0 0.9 0.0054 16.4 0.4 1.5 1 1 0 1 1 1 1 HD domain Arg_tRNA_synt_N PF03485.11 ABX13409.1 - 0.022 15.2 0.2 0.039 14.5 0.1 1.4 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain UME PF08064.8 ABX13409.1 - 0.13 12.2 0.8 2.2 8.2 0.1 2.3 2 0 0 2 2 2 0 UME (NUC010) domain FAD_binding_2 PF00890.19 ABX13410.1 - 8.5e-08 31.4 0.2 9e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 ABX13410.1 - 1.8e-05 23.6 0.3 0.0016 17.1 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.19 ABX13410.1 - 3.6e-05 22.8 0.0 0.12 11.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 ABX13410.1 - 3.7e-05 22.9 0.0 7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ABX13410.1 - 0.00044 19.4 0.1 0.18 10.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 ABX13410.1 - 0.00083 18.3 0.0 0.0015 17.5 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 ABX13410.1 - 0.0045 17.3 0.6 1.3 9.4 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ABX13410.1 - 0.0051 16.7 2.9 0.019 14.8 2.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ABX13410.1 - 0.023 13.1 0.2 0.53 8.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 ABX13410.1 - 0.029 13.4 0.0 0.23 10.5 0.0 2.2 2 0 0 2 2 2 0 Thi4 family GDI PF00996.13 ABX13410.1 - 0.072 11.3 0.0 0.14 10.4 0.0 1.5 1 0 0 1 1 1 0 GDP dissociation inhibitor NAD_binding_8 PF13450.1 ABX13410.1 - 0.079 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AAA_5 PF07728.9 ABX13411.1 - 2.2e-23 82.5 0.0 3.3e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 ABX13411.1 - 2.4e-12 46.5 0.0 3.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 ABX13411.1 - 1.1e-07 32.0 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 ABX13411.1 - 1.2e-05 24.8 0.1 2.9e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 ABX13411.1 - 2e-05 24.4 0.0 4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ABX13411.1 - 9.7e-05 22.4 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 ABX13411.1 - 0.00013 21.1 0.2 0.0043 16.1 0.1 2.6 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 ABX13411.1 - 0.00016 21.4 0.1 0.00032 20.4 0.1 1.6 1 1 0 1 1 1 1 Archaeal ATPase CbbQ_C PF08406.5 ABX13411.1 - 0.00018 21.4 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal Sigma54_activ_2 PF14532.1 ABX13411.1 - 0.0009 19.2 0.0 0.003 17.5 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 ABX13411.1 - 0.0015 18.6 0.2 0.0035 17.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 ABX13411.1 - 0.0016 18.8 0.1 0.0055 17.2 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein UPF0079 PF02367.12 ABX13411.1 - 0.0031 17.1 0.1 0.0063 16.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 ABX13411.1 - 0.0032 16.6 0.0 0.64 9.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 ABX13411.1 - 0.0041 17.9 0.2 0.0077 17.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 ABX13411.1 - 0.011 15.2 0.1 0.03 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 ABX13411.1 - 0.013 15.3 0.1 0.019 14.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 ABX13411.1 - 0.018 14.7 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 ABX13411.1 - 0.018 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.10 ABX13411.1 - 0.038 12.6 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_29 PF13555.1 ABX13411.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 ABX13411.1 - 0.071 12.2 0.1 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 ABX13411.1 - 0.075 13.3 0.4 0.13 12.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 ABX13411.1 - 0.098 11.6 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_25 PF13481.1 ABX13411.1 - 0.12 11.7 0.1 0.24 10.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 ABX13411.1 - 0.13 11.9 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 ABX13411.1 - 0.13 12.5 0.3 0.19 12.0 0.2 1.8 1 1 0 1 1 1 0 ABC transporter VWA PF00092.23 ABX13412.1 - 1.7e-08 34.4 0.0 3.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 ABX13412.1 - 3.4e-08 33.7 0.0 5.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 ABX13412.1 - 0.00033 20.3 0.0 0.00065 19.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 ABX13412.1 - 0.0054 16.5 0.0 0.027 14.2 0.0 2.2 2 1 0 2 2 2 1 vWA found in TerF C terminus PALP PF00291.20 ABX13413.1 - 2.9e-24 85.8 0.1 3.6e-23 82.2 0.0 2.5 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme TIP49 PF06068.8 ABX13413.1 - 0.006 15.3 0.1 0.013 14.1 0.1 1.5 1 0 0 1 1 1 1 TIP49 C-terminus ASCH PF04266.9 ABX13414.1 - 2e-11 44.1 0.1 2.7e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 ASCH domain DUF3850 PF12961.2 ABX13414.1 - 0.018 14.9 0.5 0.38 10.7 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3850) TBP PF00352.16 ABX13415.1 - 3.7e-61 202.4 0.1 1.4e-30 104.5 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 ABX13415.1 - 5e-05 23.2 0.0 0.041 13.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Synuclein PF01387.12 ABX13415.1 - 0.12 12.2 1.5 0.22 11.4 0.3 1.8 2 0 0 2 2 2 0 Synuclein NERD PF08378.6 ABX13417.1 - 0.0013 19.0 1.2 0.042 14.1 0.1 2.2 2 0 0 2 2 2 2 Nuclease-related domain A2M_N PF01835.14 ABX13418.1 - 0.015 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 MG2 domain FlgD_ig PF13860.1 ABX13418.1 - 0.08 12.6 0.4 0.32 10.7 0.3 2.0 1 1 0 1 1 1 0 FlgD Ig-like domain Cadherin-like PF12733.2 ABX13418.1 - 0.11 12.8 2.0 0.31 11.3 1.1 2.1 1 1 0 1 1 1 0 Cadherin-like beta sandwich domain SKG6 PF08693.5 ABX13418.1 - 0.23 10.7 4.1 0.48 9.7 2.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1628 PF07790.6 ABX13418.1 - 0.29 11.9 3.4 1.1 10.0 2.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) P-II PF00543.17 ABX13419.1 - 1.2e-11 44.9 2.4 1.5e-11 44.6 1.6 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II AsnC_trans_reg PF01037.16 ABX13420.1 - 1.7e-13 50.0 0.1 2e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 AsnC family Dus PF01207.12 ABX13421.1 - 9.8e-74 247.9 0.0 1.2e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 ABX13421.1 - 4.6e-07 29.0 0.0 7.1e-05 21.9 0.0 2.1 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Oxidored_FMN PF00724.15 ABX13421.1 - 8.8e-07 28.2 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NanE PF04131.9 ABX13421.1 - 2.5e-05 23.3 0.0 0.00011 21.2 0.0 1.9 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 ABX13421.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein NIR_SIR_ferr PF03460.12 ABX13421.1 - 0.05 13.2 0.3 0.26 10.9 0.0 2.3 3 0 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain FMN_dh PF01070.13 ABX13421.1 - 0.094 11.5 0.1 0.31 9.8 0.0 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase B12-binding PF02310.14 ABX13421.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain TSP_3 PF02412.13 ABX13422.1 - 1e-28 98.4 205.2 0.0017 17.7 1.8 26.1 25 7 1 27 27 27 16 Thrombospondin type 3 repeat TSP_3 PF02412.13 ABX13423.1 - 3.1e-39 132.1 193.5 0.00027 20.3 0.3 26.2 22 8 5 27 27 27 16 Thrombospondin type 3 repeat TSP_3 PF02412.13 ABX13424.1 - 1.1e-34 117.5 265.9 0.0017 17.7 2.1 28.1 24 13 2 26 26 26 19 Thrombospondin type 3 repeat DUF282 PF03380.9 ABX13424.1 - 0.0038 16.9 18.5 1.4 8.6 0.1 8.4 10 0 0 10 10 10 3 Caenorhabditis protein of unknown function, DUF282 Wyosine_form PF08608.7 ABX13425.1 - 7.4e-19 67.6 0.0 3.5e-18 65.4 0.0 2.2 2 1 0 2 2 2 1 Wyosine base formation Radical_SAM PF04055.16 ABX13425.1 - 6.6e-18 65.4 0.0 3e-17 63.2 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 ABX13425.1 - 0.0069 16.3 0.1 0.056 13.4 0.1 2.3 1 1 0 1 1 1 1 4Fe-4S single cluster domain SAS4 PF15460.1 ABX13425.1 - 0.028 14.2 0.3 0.077 12.8 0.1 1.9 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Ham1p_like PF01725.11 ABX13426.1 - 2.8e-47 160.5 0.1 3.2e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Torsin PF06309.6 ABX13426.1 - 0.0066 16.3 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Torsin ArsC PF03960.10 ABX13426.1 - 0.068 13.2 0.1 0.22 11.5 0.1 1.9 1 1 1 2 2 2 0 ArsC family Pkinase PF00069.20 ABX13427.1 - 4.3e-13 49.0 0.6 5.5e-13 48.6 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 ABX13427.1 - 4.7e-10 39.1 0.1 6.3e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 ABX13427.1 - 7.4e-07 28.4 0.0 8.7e-06 24.9 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 ABX13427.1 - 1.2e-05 24.5 0.1 1.8e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ABX13427.1 - 0.00011 22.0 0.0 0.00088 19.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 ABX13427.1 - 0.005 15.5 0.2 0.0077 14.9 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) WaaY PF06176.6 ABX13427.1 - 0.0059 15.8 0.4 0.0076 15.4 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Tox-URI2 PF15653.1 ABX13427.1 - 0.08 13.1 2.0 10 6.3 1.2 2.3 2 0 0 2 2 2 0 URI fold toxin 2 Peptidase_M22 PF00814.20 ABX13429.1 - 1e-72 244.8 0.0 1.2e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DUF512 PF04459.7 ABX13429.1 - 0.0081 15.2 0.0 0.018 14.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF512) CmcH_NodU PF02543.10 ABX13429.1 - 0.068 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase MMR_HSR1_C PF08438.5 ABX13430.1 - 3.2e-30 104.5 0.0 8.1e-30 103.2 0.0 1.7 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 ABX13430.1 - 7.7e-18 64.5 0.0 9.6e-17 61.0 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 ABX13430.1 - 3.6e-10 39.5 0.1 9e-10 38.2 0.1 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 ABX13430.1 - 6e-06 25.6 0.2 2.2e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B YchF-GTPase_C PF06071.8 ABX13430.1 - 0.017 14.9 0.0 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF933) zf-CCHC_5 PF14787.1 ABX13430.1 - 0.1 12.0 0.7 3.4 7.2 0.0 2.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger AAA_18 PF13238.1 ABX13431.1 - 1.2e-18 67.6 1.4 1.2e-18 67.6 1.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ABX13431.1 - 7.6e-12 46.1 0.5 9.1e-12 45.8 0.3 1.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 ABX13431.1 - 4e-08 33.3 0.7 1e-05 25.5 0.0 2.3 1 1 1 2 2 2 2 Cytidylate kinase-like family SKI PF01202.17 ABX13431.1 - 2.8e-06 27.3 0.4 5.1e-06 26.4 0.3 1.5 1 1 0 1 1 1 1 Shikimate kinase KTI12 PF08433.5 ABX13431.1 - 0.00021 20.5 0.2 0.00045 19.5 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA PF00004.24 ABX13431.1 - 0.0015 18.7 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 ABX13431.1 - 0.0024 17.7 0.3 0.019 14.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 ABX13431.1 - 0.0029 17.5 0.1 0.0056 16.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 ABX13431.1 - 0.0042 16.8 2.7 0.01 15.5 1.6 2.1 1 1 0 1 1 1 1 NTPase CoaE PF01121.15 ABX13431.1 - 0.0086 15.4 0.1 0.031 13.6 0.0 1.9 1 1 1 2 2 2 1 Dephospho-CoA kinase AAA_33 PF13671.1 ABX13431.1 - 0.017 14.9 0.0 0.031 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ABX13431.1 - 0.051 13.7 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 ABX13431.1 - 0.056 12.2 1.0 0.34 9.6 0.2 2.3 2 1 1 3 3 3 0 ArgK protein DUF258 PF03193.11 ABX13431.1 - 0.098 11.8 0.1 0.21 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TGT PF01702.13 ABX13432.1 - 3.2e-49 167.3 0.0 4.3e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Fer4 PF00037.22 ABX13433.1 - 1.7e-11 43.1 10.3 6.6e-06 25.5 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 ABX13433.1 - 2.1e-10 40.0 7.5 3.6e-05 23.4 1.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 ABX13433.1 - 1.2e-09 38.3 3.8 1.7e-09 37.8 2.6 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 ABX13433.1 - 5.7e-09 35.6 3.2 9.5e-09 34.9 2.3 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 ABX13433.1 - 7.7e-09 34.9 9.0 0.00011 21.9 1.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 ABX13433.1 - 4.2e-08 32.9 1.4 6.2e-08 32.3 1.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_13 PF13370.1 ABX13433.1 - 2.7e-06 27.6 5.0 0.008 16.5 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 ABX13433.1 - 3.1e-06 27.6 8.7 0.00094 19.7 6.2 2.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_4 PF12800.2 ABX13433.1 - 1.7e-05 24.7 9.7 0.038 14.3 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 ABX13433.1 - 2e-05 24.7 6.3 9.2e-05 22.6 4.5 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 ABX13433.1 - 0.00015 21.6 5.0 0.00042 20.2 3.4 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 ABX13433.1 - 0.00017 22.2 1.6 0.53 11.0 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 ABX13433.1 - 0.0002 21.6 11.3 0.044 14.3 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 ABX13433.1 - 0.0023 18.2 6.4 0.05 13.9 4.4 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 ABX13433.1 - 0.0037 17.6 6.8 0.19 12.1 1.6 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain DUF3000 PF11452.3 ABX13434.1 - 0.027 13.7 0.3 0.027 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) Beta-Casp PF10996.3 ABX13435.1 - 2.8e-22 78.9 0.0 5.9e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 ABX13435.1 - 2.1e-14 53.6 0.0 6.2e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ABX13435.1 - 1.1e-13 51.2 0.0 1.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 ABX13435.1 - 1.3e-13 50.5 0.0 4e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 ABX13435.1 - 9.9e-06 25.3 0.0 3.3e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain OGG_N PF07934.7 ABX13436.1 - 1.3e-15 57.4 2.6 1.1e-14 54.4 0.2 2.9 2 1 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 ABX13436.1 - 2.1e-12 47.2 0.0 3.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein LMP PF04778.7 ABX13436.1 - 0.024 14.3 3.8 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 LMP repeated region DUF3579 PF12112.3 ABX13437.1 - 0.055 13.3 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) DUF4361 PF14274.1 ABX13437.1 - 0.063 12.9 1.9 0.078 12.6 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4361) DoxA PF07680.6 ABX13437.1 - 0.075 12.6 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 TQO small subunit DoxA GvpO PF05800.6 ABX13437.1 - 0.083 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO Big_5 PF13205.1 ABX13437.1 - 0.11 13.1 0.3 0.14 12.7 0.2 1.3 1 1 0 1 1 1 0 Bacterial Ig-like domain Arrestin_C PF02752.17 ABX13437.1 - 0.14 12.2 1.1 0.23 11.5 0.8 1.4 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Copper-bind PF00127.15 ABX13438.1 - 6.3e-07 29.5 0.0 8.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family CbiM PF01891.11 ABX13438.1 - 0.034 13.7 0.4 0.045 13.3 0.3 1.1 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Cytochrom_B_N_2 PF13631.1 ABX13439.1 - 1.8e-23 83.1 10.1 1.8e-23 83.1 7.0 3.9 4 1 0 4 4 4 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 ABX13439.1 - 7.4e-07 29.3 3.7 7.4e-07 29.3 2.6 3.5 4 1 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD DUF4405 PF14358.1 ABX13439.1 - 0.0029 17.7 3.2 0.0029 17.7 2.2 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4405) S1FA PF04689.8 ABX13439.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.6 3 0 0 3 3 3 0 DNA binding protein S1FA Rieske PF00355.21 ABX13440.1 - 2.6e-08 33.3 0.0 4.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain TAT_signal PF10518.4 ABX13440.1 - 0.00099 18.9 0.9 0.0018 18.1 0.6 1.5 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.4 ABX13440.1 - 0.0017 17.4 0.1 0.0039 16.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Peptidase_S8 PF00082.17 ABX13441.1 - 6.1e-29 101.0 0.3 2.5e-28 99.0 0.2 2.0 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 ABX13441.1 - 0.026 14.9 0.1 0.026 14.9 0.0 2.9 3 0 0 3 3 3 0 Fn3-like domain (DUF1034) Cna_B PF05738.8 ABX13442.1 - 0.00024 20.7 0.8 0.0012 18.6 0.1 2.5 3 0 0 3 3 3 1 Cna protein B-type domain Reo_sigmaC PF04582.7 ABX13442.1 - 0.0032 16.6 1.5 0.0061 15.7 1.0 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Flagellin_C PF00700.16 ABX13442.1 - 0.052 13.7 0.4 0.12 12.5 0.3 1.6 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Y_Y_Y PF07495.8 ABX13442.1 - 0.061 13.0 0.5 0.81 9.4 0.0 2.6 3 0 0 3 3 3 0 Y_Y_Y domain Ran-binding PF05508.6 ABX13442.1 - 0.086 11.7 0.5 0.12 11.1 0.4 1.2 1 0 0 1 1 1 0 RanGTP-binding protein MtrB PF05440.7 ABX13442.1 - 0.1 12.6 0.3 0.47 10.5 0.1 2.3 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Big_3_4 PF13754.1 ABX13442.1 - 0.14 12.5 2.8 2.8 8.3 1.0 2.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) He_PIG PF05345.7 ABX13442.1 - 0.14 12.2 10.4 3.3 7.7 0.1 4.0 3 2 0 3 3 3 0 Putative Ig domain ThiF PF00899.16 ABX13444.1 - 3.2e-46 156.5 1.1 6.8e-46 155.4 0.7 1.6 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 ABX13444.1 - 5.3e-19 67.6 0.0 9.8e-19 66.7 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain ThiS PF02597.15 ABX13444.1 - 5.6e-10 39.5 0.0 2.2e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 ThiS family Shikimate_DH PF01488.15 ABX13444.1 - 0.00013 22.0 0.2 0.00049 20.2 0.2 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 ABX13444.1 - 0.008 16.4 0.3 0.023 14.9 0.2 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.12 ABX13444.1 - 0.026 14.9 0.1 0.13 12.6 0.1 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 ABX13444.1 - 0.081 12.0 0.1 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PALP PF00291.20 ABX13445.1 - 3e-63 213.8 0.4 3.5e-63 213.6 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACP_syn_III_C PF08541.5 ABX13445.1 - 0.041 13.9 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal WSS_VP PF12175.3 ABX13446.1 - 0.22 10.5 1.5 0.29 10.1 1.1 1.2 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP PRA-CH PF01502.13 ABX13447.1 - 3.8e-34 116.1 0.0 4.6e-34 115.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase DUF2045 PF09741.4 ABX13447.1 - 0.084 11.9 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2045) His_biosynth PF00977.16 ABX13448.1 - 7.6e-83 277.2 1.6 8.8e-83 277.0 1.1 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.12 ABX13448.1 - 5.4e-08 32.0 0.0 0.00044 19.1 0.0 2.2 1 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.10 ABX13448.1 - 7.7e-06 25.2 0.3 0.0063 15.7 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase PcrB PF01884.12 ABX13448.1 - 4.8e-05 22.7 1.6 0.00021 20.6 0.1 2.4 2 1 0 2 2 2 1 PcrB family TMP-TENI PF02581.12 ABX13448.1 - 0.00011 21.3 0.3 0.23 10.5 0.0 2.3 2 0 0 2 2 2 2 Thiamine monophosphate synthase/TENI ThiG PF05690.9 ABX13448.1 - 0.00043 19.4 0.7 0.57 9.2 0.1 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 ABX13448.1 - 0.0041 16.1 0.0 0.044 12.7 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase IMPDH PF00478.20 ABX13448.1 - 0.012 14.5 1.3 0.078 11.8 0.2 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.15 ABX13448.1 - 0.015 13.8 0.1 0.024 13.1 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain TRI9 PF08195.6 ABX13448.1 - 0.055 13.1 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 TRI9 protein Oxidored_FMN PF00724.15 ABX13448.1 - 0.061 12.3 0.1 5.3 5.9 0.0 2.2 2 0 0 2 2 2 0 NADH:flavin oxidoreductase / NADH oxidase family DUF3931 PF13082.1 ABX13448.1 - 0.11 12.3 0.2 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3931) His_biosynth PF00977.16 ABX13449.1 - 1.8e-71 240.0 1.3 2e-71 239.9 0.9 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.12 ABX13449.1 - 1.8e-06 27.3 1.0 0.015 14.5 0.1 2.1 2 0 0 2 2 2 2 PcrB family IGPS PF00218.16 ABX13449.1 - 7.5e-05 21.8 0.2 0.11 11.5 0.0 2.1 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase NMO PF03060.10 ABX13449.1 - 0.0017 17.6 0.0 0.26 10.4 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase Trp_syntA PF00290.15 ABX13449.1 - 0.0033 15.9 1.0 0.67 8.4 0.1 2.5 3 0 0 3 3 3 2 Tryptophan synthase alpha chain ThiG PF05690.9 ABX13449.1 - 0.013 14.5 0.1 0.43 9.6 0.0 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG BtpA PF03437.10 ABX13449.1 - 0.017 14.3 0.5 0.13 11.4 0.1 2.1 2 0 0 2 2 2 0 BtpA family TMP-TENI PF02581.12 ABX13449.1 - 0.061 12.4 0.0 9.9 5.2 0.0 2.5 2 1 0 2 2 2 0 Thiamine monophosphate synthase/TENI Dus PF01207.12 ABX13449.1 - 0.075 11.8 0.2 3 6.5 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Ribul_P_3_epim PF00834.14 ABX13449.1 - 0.13 11.3 1.2 12 4.8 0.0 2.9 3 0 0 3 3 3 0 Ribulose-phosphate 3 epimerase family GATase PF00117.23 ABX13450.1 - 6.3e-32 110.5 0.0 7.3e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 ABX13450.1 - 0.00012 21.7 0.0 0.00087 18.9 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 ABX13450.1 - 0.00015 21.2 1.4 0.009 15.4 1.0 2.8 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 ABX13450.1 - 0.0061 16.1 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain IGPD PF00475.13 ABX13451.1 - 2.2e-49 167.0 1.6 2.9e-49 166.6 1.1 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF916 PF06030.7 ABX13451.1 - 0.01 15.6 0.3 0.034 13.9 0.0 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF916) HAD_2 PF13419.1 ABX13452.1 - 2.6e-10 40.7 0.1 2.4e-05 24.6 0.0 2.3 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ABX13452.1 - 8.8e-06 26.2 0.0 0.0056 17.1 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ABX13452.1 - 0.00015 21.3 0.0 0.00044 19.9 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 ABX13452.1 - 0.00072 19.7 0.0 0.0013 18.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 ABX13452.1 - 0.043 13.7 0.1 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.16 ABX13453.1 - 3.2e-50 171.1 0.0 3.5e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 ABX13453.1 - 4.4e-07 28.8 0.0 5.8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Allinase Aminotran_5 PF00266.14 ABX13453.1 - 0.04 12.6 0.0 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V Histidinol_dh PF00815.15 ABX13454.1 - 1.1e-125 419.4 1.2 1.4e-125 419.2 0.8 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase DNA_Packaging PF11053.3 ABX13454.1 - 0.25 10.9 2.0 0.27 10.8 0.0 2.0 3 0 0 3 3 3 0 Terminase DNA packaging enzyme HisG PF01634.13 ABX13455.1 - 3.6e-36 124.2 0.0 4.8e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 ABX13455.1 - 5.8e-13 48.5 0.0 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain HMG-CoA_red PF00368.13 ABX13456.1 - 1e-85 287.6 4.0 1.2e-85 287.4 2.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase GSDH PF07995.6 ABX13457.1 - 4e-86 289.0 0.0 5.1e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 ABX13457.1 - 3.5e-06 26.6 0.0 0.021 14.7 0.0 3.6 3 1 0 3 3 3 2 NHL repeat Reg_prop PF07494.6 ABX13457.1 - 0.00012 21.6 0.5 7.4 6.9 0.0 4.2 3 0 0 3 3 3 1 Two component regulator propeller PQQ_3 PF13570.1 ABX13457.1 - 0.0036 17.5 0.2 14 6.1 0.0 4.3 5 0 0 5 5 5 1 PQQ-like domain SGL PF08450.7 ABX13457.1 - 0.048 13.0 0.0 5.3 6.3 0.0 2.6 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Big_3 PF07523.7 ABX13457.1 - 0.11 12.6 0.1 5.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF1743 PF08489.6 ABX13458.1 - 8.1e-37 125.5 0.0 2.7e-36 123.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1743) OrfB_Zn_ribbon PF07282.6 ABX13458.1 - 0.0045 16.6 0.6 0.01 15.4 0.4 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain C1_1 PF00130.17 ABX13458.1 - 0.94 9.2 4.2 1.8 8.3 2.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Diphthamide_syn PF01866.12 ABX13459.1 - 5.3e-82 275.4 0.0 6.6e-82 275.1 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Fe-ADH_2 PF13685.1 ABX13459.1 - 0.39 9.9 2.3 0.39 9.9 0.3 1.8 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase TPR_11 PF13414.1 ABX13460.1 - 9.8e-23 79.5 6.5 3.9e-13 48.8 1.7 3.0 1 1 3 4 4 4 4 TPR repeat TPR_1 PF00515.23 ABX13460.1 - 3.4e-19 67.5 1.8 1.7e-07 30.5 0.6 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ABX13460.1 - 2.5e-17 61.3 0.1 9.4e-06 25.1 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ABX13460.1 - 2.8e-16 59.6 0.0 3.8e-08 33.7 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 ABX13460.1 - 3.2e-12 46.5 0.0 5.2e-07 29.9 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ABX13460.1 - 1.1e-11 44.4 0.1 2.9e-07 30.3 0.4 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ABX13460.1 - 2.4e-11 43.3 0.0 0.047 14.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ABX13460.1 - 6.6e-10 38.9 11.1 0.0002 21.4 0.4 2.6 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 ABX13460.1 - 9.4e-09 34.4 7.3 0.0021 17.6 0.7 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ABX13460.1 - 5.1e-08 32.8 0.0 0.18 12.5 0.0 4.3 1 1 3 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ABX13460.1 - 5.6e-08 32.5 0.6 0.1 12.4 0.0 4.3 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 ABX13460.1 - 5.3e-07 29.3 5.3 0.0026 17.8 0.3 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 ABX13460.1 - 3.6e-06 26.3 0.6 0.082 12.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ABX13460.1 - 6e-05 22.8 0.0 0.00029 20.6 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ABX13460.1 - 0.0012 18.6 0.0 0.94 9.4 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 ABX13460.1 - 0.0016 18.2 2.0 0.13 12.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR PF01535.15 ABX13460.1 - 0.011 15.6 0.5 9 6.5 0.0 3.6 4 0 0 4 4 4 0 PPR repeat ATP13 PF12921.2 ABX13460.1 - 0.028 13.7 0.1 0.66 9.3 0.0 2.4 1 1 1 2 2 2 0 Mitochondrial ATPase expression MIT PF04212.13 ABX13460.1 - 0.068 13.0 1.5 12 5.8 0.1 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ADH_zinc_N PF00107.21 ABX13461.1 - 7.7e-30 103.1 0.0 1.4e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ABX13461.1 - 1.6e-26 92.2 0.3 2.6e-26 91.5 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ABX13461.1 - 1.9e-16 61.1 0.0 3.5e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.5 ABX13461.1 - 0.072 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal C1_2 PF03107.11 ABX13461.1 - 0.15 12.1 4.7 0.26 11.4 3.2 1.4 1 0 0 1 1 1 0 C1 domain EXOSC1 PF10447.4 ABX13462.1 - 0.00059 19.7 0.4 0.037 13.9 0.1 2.4 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 ABX13462.1 - 0.001 18.3 0.0 0.0033 16.6 0.0 1.9 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region Prok-RING_1 PF14446.1 ABX13462.1 - 0.0017 18.0 1.4 0.0038 16.9 1.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 DNA_RNApol_7kD PF03604.8 ABX13462.1 - 0.57 9.7 5.6 2.4 7.6 3.9 2.1 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 ABX13462.1 - 1.1 8.9 3.5 3.4 7.4 2.5 1.8 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family PDT PF00800.13 ABX13463.1 - 1.4e-59 200.6 0.3 1.8e-59 200.3 0.2 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 ABX13463.1 - 0.00016 21.1 0.0 0.00033 20.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain PetM PF08041.6 ABX13464.1 - 0.023 14.1 0.4 0.023 14.1 0.3 2.2 3 0 0 3 3 3 0 PetM family of cytochrome b6f complex subunit 7 IMPDH PF00478.20 ABX13465.1 - 1.3e-135 451.8 7.3 1.4e-135 451.7 5.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 ABX13465.1 - 3.9e-26 90.5 1.4 8.2e-12 44.7 0.2 3.0 3 0 0 3 3 3 2 CBS domain NMO PF03060.10 ABX13465.1 - 1.6e-10 40.7 7.2 1.5e-05 24.3 3.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 ABX13465.1 - 4.8e-07 28.9 7.2 2e-06 26.9 5.0 2.2 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 ABX13465.1 - 2.3e-06 27.0 1.4 0.018 14.3 0.1 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein DHO_dh PF01180.16 ABX13465.1 - 0.00014 20.9 6.4 0.00062 18.8 0.8 2.5 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase NanE PF04131.9 ABX13465.1 - 0.0017 17.3 2.0 0.0017 17.3 1.4 2.2 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 ABX13465.1 - 0.039 13.0 2.5 0.051 12.6 0.5 2.1 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG PcrB PF01884.12 ABX13465.1 - 0.042 13.0 7.8 2.2 7.4 0.2 3.9 3 2 1 5 5 5 0 PcrB family Pterin_bind PF00809.17 ABX13466.1 - 1.2e-36 126.0 0.5 2.7e-36 124.9 0.4 1.5 1 1 0 1 1 1 1 Pterin binding enzyme DUF1792 PF08759.6 ABX13466.1 - 0.076 12.6 0.3 0.75 9.3 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF1792) MAF_flag10 PF01973.13 ABX13467.1 - 1.6e-44 151.4 0.4 2.3e-44 150.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF115 TPK_catalytic PF04263.11 ABX13467.1 - 0.012 15.1 0.2 0.28 10.7 0.0 2.2 1 1 1 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain PmbA_TldD PF01523.11 ABX13468.1 - 0.017 14.4 0.2 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase IATP PF04568.7 ABX13468.1 - 0.06 13.3 0.6 0.06 13.3 0.4 1.8 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF4094 PF13334.1 ABX13468.1 - 0.088 13.1 1.9 0.12 12.7 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF2443 PF10398.4 ABX13468.1 - 6.2 6.6 6.9 27 4.6 0.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2443) GATase PF00117.23 ABX13469.1 - 1.2e-41 142.2 0.0 1.8e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 ABX13469.1 - 2.8e-31 107.0 0.0 6.2e-31 105.9 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 ABX13469.1 - 8.9e-11 41.1 0.3 8.3e-06 24.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 ABX13469.1 - 6.6e-08 32.2 0.0 2.3e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 ABX13469.1 - 0.00015 21.2 0.0 0.0032 16.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 ABX13469.1 - 0.00046 18.8 0.0 0.0029 16.2 0.0 2.0 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 ABX13469.1 - 0.003 17.1 0.0 0.0084 15.6 0.0 1.7 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.8 ABX13469.1 - 0.023 13.9 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC DUF2024 PF09630.5 ABX13471.1 - 6.2e-37 125.1 2.6 6.8e-37 125.0 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) ROK PF00480.15 ABX13472.1 - 2.6e-49 167.4 0.6 3.2e-49 167.1 0.4 1.1 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.15 ABX13472.1 - 0.00011 21.6 0.1 0.00072 18.9 0.1 2.2 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hydant_A_N PF05378.8 ABX13472.1 - 0.0066 15.9 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region RasGAP_C PF03836.10 ABX13472.1 - 0.087 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 RasGAP C-terminus Cpn60_TCP1 PF00118.19 ABX13473.1 - 1.5e-165 551.5 18.3 1.8e-165 551.2 12.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Adenine_deam_C PF13382.1 ABX13474.1 - 1e-47 161.5 0.0 1.5e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.15 ABX13474.1 - 6.9e-16 58.8 0.0 4.2e-14 52.9 0.0 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 ABX13474.1 - 8.9e-11 41.4 0.2 4e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 ABX13474.1 - 0.0014 17.9 0.0 0.4 9.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 ABX13474.1 - 0.02 14.9 0.0 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase Ribosomal_L44 PF00935.14 ABX13475.1 - 9e-26 89.6 8.5 9e-26 89.6 5.9 1.6 1 1 1 2 2 2 1 Ribosomal protein L44 Rdx PF10262.4 ABX13475.1 - 1.1 9.3 3.2 0.37 10.8 0.3 1.7 2 0 0 2 2 2 0 Rdx family Ribosomal_L33 PF00471.15 ABX13475.1 - 5.8 7.2 8.9 0.32 11.2 1.0 2.4 2 1 0 2 2 2 0 Ribosomal protein L33 Ribosomal_S27e PF01667.12 ABX13476.1 - 3.3e-17 61.7 0.8 3.9e-17 61.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 Zn_Tnp_IS91 PF14319.1 ABX13476.1 - 0.0017 17.8 1.1 0.002 17.6 0.7 1.1 1 0 0 1 1 1 1 Transposase zinc-binding domain zinc_ribbon_6 PF14599.1 ABX13476.1 - 0.0084 15.8 2.4 0.016 14.9 1.7 1.5 1 1 0 1 1 1 1 Zinc-ribbon zf-dskA_traR PF01258.12 ABX13476.1 - 0.0093 15.6 0.3 3.1 7.6 0.0 2.2 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger ZZ PF00569.12 ABX13476.1 - 0.011 15.2 4.7 0.99 8.9 0.2 2.2 1 1 1 2 2 2 0 Zinc finger, ZZ type TF_Zn_Ribbon PF08271.7 ABX13476.1 - 0.013 14.8 0.2 0.017 14.4 0.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding YhfH PF14149.1 ABX13476.1 - 0.023 14.4 1.1 2.1 8.2 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein zf-BED PF02892.10 ABX13476.1 - 0.027 14.2 1.8 3.2 7.5 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger zf-CHY PF05495.7 ABX13476.1 - 0.036 14.2 1.3 0.045 13.9 0.9 1.2 1 0 0 1 1 1 0 CHY zinc finger RNA_POL_M_15KD PF02150.11 ABX13476.1 - 0.037 13.6 0.8 0.053 13.2 0.5 1.3 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit HypA PF01155.14 ABX13476.1 - 0.038 13.6 0.6 0.045 13.4 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 ABX13476.1 - 0.045 13.5 2.1 0.083 12.7 1.5 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 ABX13476.1 - 0.063 12.5 4.3 1.2 8.4 3.0 2.2 1 1 1 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 ABX13476.1 - 0.063 13.2 1.2 0.12 12.3 0.8 1.5 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_7 PF15269.1 ABX13476.1 - 0.066 13.0 0.1 0.076 12.8 0.1 1.1 1 0 0 1 1 1 0 Zinc-finger zf-C4_Topoisom PF01396.14 ABX13476.1 - 0.067 12.7 0.4 8.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-UDP PF14569.1 ABX13476.1 - 0.068 12.9 0.3 0.077 12.7 0.2 1.1 1 0 0 1 1 1 0 Zinc-binding RING-finger Lar_restr_allev PF14354.1 ABX13476.1 - 0.077 13.3 2.4 2.3 8.5 0.1 2.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF2318 PF10080.4 ABX13476.1 - 0.087 12.5 0.6 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) OrfB_Zn_ribbon PF07282.6 ABX13476.1 - 0.1 12.2 0.7 0.11 12.1 0.5 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.1 ABX13476.1 - 0.12 11.8 1.0 8.2 6.0 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 ABX13476.1 - 0.12 12.1 1.1 0.18 11.6 0.8 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain RRN7 PF11781.3 ABX13476.1 - 0.17 11.3 0.9 8 6.0 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 C1_1 PF00130.17 ABX13476.1 - 0.21 11.3 1.5 0.37 10.5 1.0 1.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_RNApol_7kD PF03604.8 ABX13476.1 - 0.23 10.9 4.0 3.7 7.0 0.3 2.2 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Elf1 PF05129.8 ABX13476.1 - 0.37 10.4 2.7 0.57 9.9 1.9 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Rpr2 PF04032.11 ABX13476.1 - 0.46 10.3 2.6 3.7 7.4 1.8 2.0 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GCC2_GCC3 PF07699.8 ABX13476.1 - 0.49 10.0 4.3 1.5 8.4 3.0 1.7 1 1 0 1 1 1 0 GCC2 and GCC3 Eapp_C PF10238.4 ABX13476.1 - 0.64 9.9 4.4 5.5 6.8 0.3 2.1 1 1 1 2 2 2 0 E2F-associated phosphoprotein zf-HYPF PF07503.7 ABX13476.1 - 0.67 9.4 3.3 7 6.1 0.1 2.2 2 0 0 2 2 2 0 HypF finger Prok-RING_1 PF14446.1 ABX13476.1 - 0.76 9.5 3.8 5.1 6.9 2.8 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Sgf11 PF08209.6 ABX13476.1 - 0.97 8.8 3.4 7.2 6.0 0.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2_3 PF13878.1 ABX13476.1 - 1.1 8.8 5.5 2.6 7.6 0.4 2.2 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO FeS PF04060.8 ABX13476.1 - 3.6 7.2 5.8 1.3 8.6 0.4 2.5 3 0 0 3 3 3 0 Putative Fe-S cluster DUF3797 PF12677.2 ABX13476.1 - 7.3 6.2 7.6 6.2 6.5 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) NTP_transf_3 PF12804.2 ABX13477.1 - 3.9e-15 56.2 0.0 4.9e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 ABX13477.1 - 3.2e-08 33.3 0.0 4.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transferase PF00483.18 ABX13477.1 - 8.2e-05 22.0 0.1 0.00017 21.0 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase CTP_transf_3 PF02348.14 ABX13477.1 - 0.0059 16.2 0.2 0.021 14.4 0.2 1.9 1 1 0 1 1 1 1 Cytidylyltransferase SapC PF07277.6 ABX13477.1 - 0.095 11.9 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 SapC CobS PF02654.10 ABX13478.1 - 4.7e-53 180.1 19.2 5.4e-53 179.9 13.3 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase TauE PF01925.14 ABX13478.1 - 0.069 12.5 26.3 0.084 12.3 18.2 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE CobD_Cbib PF03186.8 ABX13479.1 - 1.1e-98 329.9 0.1 1.3e-98 329.6 0.1 1.1 1 0 0 1 1 1 1 CobD/Cbib protein CbiA PF01656.18 ABX13480.1 - 2.8e-27 95.4 0.1 3.9e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 ABX13480.1 - 6.5e-17 61.8 0.1 2.4e-16 59.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 ABX13480.1 - 2.9e-05 23.7 0.1 0.018 14.7 0.0 2.7 2 1 1 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 ABX13480.1 - 0.0073 16.6 0.1 0.018 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ABX13480.1 - 0.015 15.5 0.0 0.064 13.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter SelA PF03841.8 ABX13480.1 - 0.015 14.0 0.2 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase SRP54 PF00448.17 ABX13480.1 - 0.016 14.6 0.2 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 ABX13480.1 - 0.03 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 ABX13480.1 - 0.038 14.7 0.5 0.34 11.7 0.1 2.7 1 1 1 2 2 2 0 AAA domain Miro PF08477.8 ABX13480.1 - 0.039 14.4 0.2 9.2 6.7 0.0 2.6 3 0 0 3 3 2 0 Miro-like protein AAA_30 PF13604.1 ABX13480.1 - 0.11 12.1 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ABX13480.1 - 0.18 11.8 0.0 0.46 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Aminotran_1_2 PF00155.16 ABX13481.1 - 1.2e-50 172.5 0.0 1.3e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 ABX13481.1 - 1.5e-06 27.1 0.1 0.00075 18.2 0.0 2.3 2 0 0 2 2 2 2 Allinase Semialdhyde_dhC PF02774.13 ABX13482.1 - 1.6e-31 109.6 0.0 2.6e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 ABX13482.1 - 2e-28 99.1 0.1 4.4e-28 98.0 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 ABX13482.1 - 0.0079 16.1 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 ABX13482.1 - 0.012 16.1 0.1 0.023 15.2 0.1 1.5 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.11 ABX13482.1 - 0.037 14.5 0.0 0.077 13.5 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase AsnC_trans_reg PF01037.16 ABX13483.1 - 1.6e-12 46.9 0.1 2.2e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 AsnC family B-block_TFIIIC PF04182.7 ABX13483.1 - 0.02 14.7 0.1 0.03 14.1 0.0 1.6 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC UbiA PF01040.13 ABX13484.1 - 3e-22 79.0 22.9 4.1e-22 78.6 15.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Defensin_big PF14862.1 ABX13484.1 - 0.22 11.5 2.7 7.5 6.6 0.2 2.6 1 1 1 2 2 2 0 Big defensin DUF3800 PF12686.2 ABX13486.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) MscS_porin PF12795.2 ABX13486.1 - 0.08 12.2 0.8 0.14 11.4 0.4 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF3843 PF12954.2 ABX13486.1 - 0.092 11.7 6.0 0.11 11.5 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) Syntaxin-6_N PF09177.6 ABX13486.1 - 1.3 9.4 5.9 7.8 6.9 0.3 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Ndc1_Nup PF09531.5 ABX13486.1 - 4.9 5.4 7.9 5.4 5.3 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2680 PF10925.3 ABX13487.1 - 5.4e-06 26.1 36.5 2.8 7.8 0.4 10.0 12 1 0 12 12 12 5 Protein of unknown function (DUF2680) HSBP1 PF06825.7 ABX13487.1 - 0.0024 17.4 26.5 0.79 9.3 0.0 8.5 8 1 0 8 8 8 1 Heat shock factor binding protein 1 DUF3892 PF13031.1 ABX13487.1 - 0.019 15.3 0.0 0.063 13.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) HypA PF01155.14 ABX13487.1 - 0.12 12.0 3.1 0.25 11.0 2.2 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family LURAP PF14854.1 ABX13487.1 - 0.47 10.1 3.8 1.4 8.6 2.2 2.2 1 1 0 1 1 1 0 Leucine rich adaptor protein DUF3782 PF12644.2 ABX13487.1 - 1.4 8.7 35.6 1.5e+04 -22.7 24.7 7.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) CorA PF01544.13 ABX13487.1 - 1.5 7.8 30.2 1.9 7.4 4.8 4.8 4 2 1 5 5 5 0 CorA-like Mg2+ transporter protein PilJ PF13675.1 ABX13487.1 - 3.1 8.1 29.0 5 7.4 1.5 4.9 2 1 3 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term FlxA PF14282.1 ABX13487.1 - 4.5 7.2 62.5 0.06 13.2 4.5 5.2 4 1 1 5 5 5 0 FlxA-like protein DUF3865 PF12981.2 ABX13489.1 - 0.014 15.1 0.2 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Mad3_BUB1_I PF08311.7 ABX13489.1 - 0.3 10.8 4.9 3.3 7.5 0.5 2.8 2 1 1 3 3 3 0 Mad3/BUB1 homology region 1 Phtf-FEM1B_bdg PF12129.3 ABX13489.1 - 0.49 9.7 3.3 4.8 6.5 0.1 2.9 2 1 1 3 3 3 0 Male germ-cell putative homeodomain transcription factor YkyA PF10368.4 ABX13491.1 - 0.0033 16.8 3.3 0.14 11.4 0.4 2.3 1 1 1 2 2 2 2 Putative cell-wall binding lipoprotein DDE_Tnp_ISL3 PF01610.12 ABX13491.1 - 0.0038 16.8 7.0 0.078 12.5 0.2 2.2 1 1 0 2 2 2 2 Transposase SnoaL PF07366.7 ABX13491.1 - 0.0046 16.5 0.2 0.0088 15.6 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase ERp29 PF07749.7 ABX13491.1 - 0.01 16.4 2.0 2.8 8.6 0.1 2.2 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Moulting_cycle PF04870.11 ABX13491.1 - 0.017 14.2 7.5 0.091 11.8 1.5 2.1 1 1 1 2 2 2 0 Moulting cycle Mating_N PF12731.2 ABX13491.1 - 0.04 13.7 4.9 0.11 12.4 0.6 3.0 1 1 1 2 2 2 0 Mating-type protein beta 1 CDC37_C PF08564.5 ABX13491.1 - 0.052 13.3 1.4 8.5 6.2 0.0 2.9 1 1 1 3 3 3 0 Cdc37 C terminal domain ATP-synt_G PF04718.10 ABX13491.1 - 0.12 13.0 0.8 0.34 11.5 0.1 1.9 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit ALIX_LYPXL_bnd PF13949.1 ABX13491.1 - 0.15 11.0 6.0 0.19 10.6 4.2 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF4381 PF14316.1 ABX13491.1 - 0.19 11.8 2.7 0.26 11.3 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DNA_repr_REX1B PF14966.1 ABX13491.1 - 0.28 11.5 1.9 1.6 9.1 0.1 2.4 1 1 2 3 3 3 0 DNA repair REX1-B U5_2-snRNA_bdg PF10597.4 ABX13491.1 - 0.59 9.7 3.5 1 8.9 1.3 1.9 1 1 1 2 2 2 0 U5-snRNA binding site 2 of PrP8 DASH_Dad2 PF08654.5 ABX13491.1 - 0.62 10.0 6.7 4.8 7.2 4.6 2.4 1 1 0 1 1 1 0 DASH complex subunit Dad2 DUF1104 PF06518.6 ABX13491.1 - 0.9 9.7 4.9 2.6 8.2 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) CMAS PF02353.15 ABX13491.1 - 1 8.3 7.0 1.1 8.2 1.1 2.2 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase MbeD_MobD PF04899.7 ABX13491.1 - 2.2 8.2 11.8 0.043 13.7 2.0 2.6 2 1 0 2 2 2 0 MbeD/MobD like PBD PF00786.23 ABX13491.1 - 3.9 7.9 10.7 12 6.4 0.2 3.6 1 1 2 3 3 3 0 P21-Rho-binding domain HMG_box_2 PF09011.5 ABX13491.1 - 4.1 7.8 17.2 0.16 12.3 1.3 3.2 1 1 2 3 3 3 0 HMG-box domain 4HBT PF03061.17 ABX13492.1 - 3.5e-14 52.6 0.1 5.1e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.14 ABX13492.1 - 0.00046 19.5 0.1 0.00095 18.5 0.1 1.5 2 0 0 2 2 2 1 MaoC like domain Caenor_Her-1 PF09232.5 ABX13492.1 - 0.036 14.1 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Caenorhabditis elegans Her-1 UbiD PF01977.11 ABX13493.1 - 3.7e-108 361.6 0.0 4.2e-108 361.4 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF1108 PF06531.6 ABX13494.1 - 0.0091 16.1 0.2 0.44 10.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1108) Pro_Al_protease PF02983.9 ABX13495.1 - 0.017 15.0 2.8 0.026 14.4 2.0 1.2 1 0 0 1 1 1 0 Alpha-lytic protease prodomain DUF3342 PF11822.3 ABX13495.1 - 0.029 13.5 6.5 0.035 13.2 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) FdhD-NarQ PF02634.10 ABX13495.1 - 0.26 10.7 2.4 0.34 10.3 1.7 1.1 1 0 0 1 1 1 0 FdhD/NarQ family Zn_ribbon_recom PF13408.1 ABX13495.1 - 0.41 10.9 0.3 0.41 10.9 0.2 2.8 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain C1_1 PF00130.17 ABX13495.1 - 0.52 10.0 12.8 0.82 9.4 1.6 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YyzF PF14116.1 ABX13495.1 - 3.8 7.5 5.6 8.8 6.3 2.2 2.6 2 1 0 2 2 2 0 YyzF-like protein Cys_rich_CPCC PF14206.1 ABX13495.1 - 6.5 6.3 11.6 0.16 11.5 0.6 2.9 2 1 0 3 3 3 0 Cysteine-rich CPCC DZR PF12773.2 ABX13495.1 - 7.2 6.5 11.4 1.6e+02 2.1 7.9 2.4 1 1 0 1 1 1 0 Double zinc ribbon DUF460 PF04312.8 ABX13496.1 - 0.0094 15.4 0.0 0.02 14.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF460) COG6 PF06419.6 ABX13497.1 - 0.0026 15.9 4.3 0.003 15.7 3.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 OmpH PF03938.9 ABX13497.1 - 0.0026 17.7 5.8 0.0029 17.5 4.0 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Mitofilin PF09731.4 ABX13497.1 - 0.0027 16.4 6.4 0.003 16.3 4.5 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein V-ATPase_G PF03179.10 ABX13497.1 - 0.014 15.7 7.1 0.019 15.2 4.9 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Spore_III_AB PF09548.5 ABX13497.1 - 0.018 14.7 1.4 0.032 13.9 0.9 1.5 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Apolipoprotein PF01442.13 ABX13497.1 - 0.02 14.4 3.4 0.038 13.4 2.4 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Ribosomal_S3_C PF00189.15 ABX13497.1 - 0.025 14.7 0.4 0.12 12.5 0.1 2.0 1 1 1 2 2 2 0 Ribosomal protein S3, C-terminal domain Phasin PF05597.6 ABX13497.1 - 0.026 14.2 7.5 0.53 10.0 0.1 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SF-assemblin PF06705.6 ABX13497.1 - 0.046 12.8 7.2 0.049 12.7 5.0 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin DUF972 PF06156.8 ABX13497.1 - 0.056 13.7 4.2 0.076 13.3 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CsoSCA PF08936.5 ABX13497.1 - 0.056 11.7 1.9 0.065 11.5 1.3 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase Reo_sigmaC PF04582.7 ABX13497.1 - 0.096 11.8 5.3 0.11 11.6 3.6 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DivIVA PF05103.8 ABX13497.1 - 0.11 12.5 7.6 0.16 12.0 5.3 1.2 1 0 0 1 1 1 0 DivIVA protein DUF883 PF05957.8 ABX13497.1 - 0.11 12.8 6.3 2.9 8.3 1.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) SlyX PF04102.7 ABX13497.1 - 0.16 12.4 2.1 0.32 11.4 1.4 1.8 1 1 0 1 1 1 0 SlyX NAP PF00956.13 ABX13497.1 - 0.29 10.2 2.8 0.38 9.8 1.8 1.3 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) HAND PF09110.6 ABX13497.1 - 0.29 11.5 2.9 0.36 11.2 2.0 1.2 1 0 0 1 1 1 0 HAND DUF3154 PF11351.3 ABX13497.1 - 0.33 10.7 3.2 0.33 10.7 1.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) Spc24 PF08286.6 ABX13497.1 - 0.39 10.4 7.0 4.5 6.9 4.8 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 LMBR1 PF04791.11 ABX13497.1 - 0.41 9.1 4.1 0.42 9.1 2.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_13 PF13166.1 ABX13497.1 - 0.63 8.4 7.0 0.71 8.2 4.9 1.0 1 0 0 1 1 1 0 AAA domain hDGE_amylase PF14701.1 ABX13497.1 - 0.74 8.6 3.9 0.78 8.5 2.7 1.0 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme NPV_P10 PF05531.7 ABX13497.1 - 0.86 9.8 5.8 6.3 7.1 4.0 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3708 PF12501.3 ABX13497.1 - 1.3 8.8 3.7 2.4 7.9 2.4 1.4 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter NAC PF01849.13 ABX13498.1 - 2e-16 59.2 0.9 3.9e-16 58.3 0.6 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 ABX13498.1 - 9.1e-07 28.5 0.3 9.1e-07 28.5 0.2 2.0 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 ABX13498.1 - 0.01 15.3 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 0 UBA-like domain ATP-synt_DE PF00401.15 ABX13498.1 - 0.12 12.3 3.1 0.21 11.5 2.1 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain FdtA PF05523.6 ABX13498.1 - 0.14 11.6 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal Cytidylate_kin2 PF13189.1 ABX13498.1 - 0.23 11.3 1.2 0.4 10.5 0.1 1.8 2 1 0 2 2 2 0 Cytidylate kinase-like family TGT_C2 PF14810.1 ABX13499.1 - 3.1e-10 39.7 0.0 4.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Patch-forming domain C2 of tRNA-guanine transglycosylase PUA PF01472.15 ABX13499.1 - 9.1e-10 38.1 0.2 1.9e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 PUA domain Sec-ASP3 PF15432.1 ABX13499.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 Neural_ProG_Cyt PF06567.6 ABX13499.1 - 0.11 12.5 0.0 1.9 8.6 0.0 2.1 1 1 1 2 2 2 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain PhoU PF01895.14 ABX13500.1 - 6.5e-29 100.2 12.6 1e-19 70.7 0.5 2.5 2 0 0 2 2 2 2 PhoU domain Antitoxin-MazE PF04014.13 ABX13500.1 - 1.6e-07 30.8 0.0 5.1e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Antidote-toxin recognition MazE KMP11 PF03037.11 ABX13500.1 - 0.038 14.5 2.6 0.081 13.5 1.4 1.8 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 HemY_N PF07219.8 ABX13500.1 - 0.064 12.8 0.1 2.5 7.6 0.0 2.9 2 1 1 3 3 3 0 HemY protein N-terminus MMR_HSR1 PF01926.18 ABX13501.1 - 1.7e-16 60.2 0.1 5.7e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ABX13501.1 - 5.4e-10 38.7 0.3 9.6e-10 37.9 0.2 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP-bdg_N PF13167.1 ABX13501.1 - 5.7e-09 35.9 0.0 1.9e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP_EFTU PF00009.22 ABX13501.1 - 8.7e-08 31.8 0.6 1.6e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 ABX13501.1 - 0.00021 20.5 0.6 0.00052 19.2 0.4 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.22 ABX13501.1 - 0.0017 18.6 0.1 0.0049 17.1 0.0 2.0 2 1 0 2 2 2 1 ABC transporter Ras PF00071.17 ABX13501.1 - 0.0066 15.8 0.6 0.028 13.7 0.4 2.0 1 1 0 1 1 1 1 Ras family DUF258 PF03193.11 ABX13501.1 - 0.0081 15.3 1.0 0.034 13.3 0.2 2.2 1 1 1 2 2 2 1 Protein of unknown function, DUF258 Trans_reg_C PF00486.23 ABX13501.1 - 0.012 15.5 0.5 0.39 10.6 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal PduV-EutP PF10662.4 ABX13501.1 - 0.041 13.3 2.7 0.92 8.9 1.4 3.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 ABX13501.1 - 0.065 13.7 0.2 0.23 11.9 0.0 2.1 2 1 0 2 2 1 0 Miro-like protein Dynamin_N PF00350.18 ABX13501.1 - 0.071 12.9 0.3 0.74 9.6 0.1 2.4 1 1 1 2 2 2 0 Dynamin family cobW PF02492.14 ABX13501.1 - 0.23 10.9 1.6 11 5.4 0.1 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Trm56 PF01994.11 ABX13502.1 - 3.9e-49 165.3 0.2 5.5e-49 164.9 0.1 1.2 1 0 0 1 1 1 1 tRNA ribose 2'-O-methyltransferase, aTrm56 SpoU_methylase PF00588.14 ABX13502.1 - 2.2e-05 24.3 0.0 3.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SPOUT_MTase_2 PF14419.1 ABX13502.1 - 0.062 12.4 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP TFIIE_alpha PF02002.12 ABX13503.1 - 1.6e-18 66.1 1.3 2.8e-18 65.3 0.9 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 ABX13503.1 - 0.015 14.6 0.6 0.029 13.6 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding TrmB PF01978.14 ABX13503.1 - 0.033 13.8 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF3834 PF12916.2 ABX13503.1 - 0.038 13.0 0.2 0.058 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) Zn_ribbon_recom PF13408.1 ABX13503.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Sigma70_r3 PF04539.11 ABX13503.1 - 0.14 12.0 1.2 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 Phe_tRNA-synt_N PF02912.13 ABX13503.1 - 0.71 9.6 4.2 12 5.6 0.5 3.0 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain zf-tcix PF14952.1 ABX13503.1 - 0.76 9.1 2.8 5.2 6.4 0.3 2.4 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding DUF2346 PF09803.4 ABX13503.1 - 4.2 7.2 6.2 0.26 11.1 0.6 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) Aldedh PF00171.17 ABX13504.1 - 1.8e-141 471.6 0.0 2e-141 471.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ABX13504.1 - 4.3e-05 22.4 0.0 6.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Hemerythrin PF01814.18 ABX13506.1 - 1.6e-11 44.4 2.5 2.4e-11 43.9 0.5 2.1 2 1 0 2 2 2 1 Hemerythrin HHE cation binding domain Methyltransf_4 PF02390.12 ABX13506.1 - 0.053 12.5 1.1 0.068 12.2 0.3 1.5 2 0 0 2 2 2 0 Putative methyltransferase IZUMO PF15005.1 ABX13506.1 - 0.19 11.7 1.3 0.26 11.3 0.2 1.7 2 0 0 2 2 2 0 Izumo sperm-egg fusion Enkurin PF13864.1 ABX13506.1 - 3.1 8.0 6.8 14 5.9 1.4 2.3 2 0 0 2 2 2 0 Calmodulin-binding SWIB PF02201.13 ABX13507.1 - 0.0051 16.4 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain RibD_C PF01872.12 ABX13508.1 - 2.7e-48 164.2 0.1 3.1e-48 164.0 0.1 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Sep15_SelM PF08806.6 ABX13508.1 - 0.042 13.5 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Sep15/SelM redox domain DUF4412 PF14371.1 ABX13508.1 - 0.11 12.9 0.1 0.21 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) Amidohydro_1 PF01979.15 ABX13509.1 - 9.5e-28 97.8 0.7 1.5e-26 93.8 0.5 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 ABX13509.1 - 8.7e-11 41.4 0.0 2.7e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 ABX13509.1 - 4.2e-07 30.2 0.0 0.027 14.5 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 ABX13509.1 - 7e-05 22.2 0.1 0.028 13.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family GGDN PF05165.7 ABX13510.1 - 2.7e-48 164.1 0.0 3.4e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 GGDN family Guanylate_cyc PF00211.15 ABX13510.1 - 0.021 14.2 0.1 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain MAF_flag10 PF01973.13 ABX13510.1 - 0.046 13.2 0.3 0.21 11.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF115 NOG1 PF06858.9 ABX13510.1 - 0.1 12.4 0.7 0.39 10.6 0.0 2.3 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) ARL2_Bind_BART PF11527.3 ABX13510.1 - 0.52 10.0 3.3 0.45 10.3 0.6 2.1 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART DMRL_synthase PF00885.14 ABX13511.1 - 1.5e-33 115.4 0.7 1.7e-33 115.3 0.5 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF3356 PF11836.3 ABX13511.1 - 0.02 14.6 0.2 0.91 9.3 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3356) DHBP_synthase PF00926.14 ABX13512.1 - 8.5e-69 230.6 0.0 9.6e-69 230.5 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PAF-AH_p_II PF03403.8 ABX13512.1 - 0.064 11.5 0.0 0.086 11.1 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Lum_binding PF00677.12 ABX13513.1 - 5.8e-48 160.7 11.8 1.3e-28 98.6 0.9 2.0 2 0 0 2 2 2 2 Lumazine binding domain NPV_P10 PF05531.7 ABX13513.1 - 0.22 11.8 1.0 0.35 11.1 0.1 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_11 PF13414.1 ABX13514.1 - 1.4e-31 107.9 14.4 4.6e-13 48.6 0.2 3.4 2 1 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 ABX13514.1 - 6.6e-26 88.8 7.8 1.6e-08 33.8 0.0 5.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 ABX13514.1 - 1.7e-20 71.1 2.9 2.8e-05 23.6 0.0 5.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 ABX13514.1 - 2.4e-18 65.8 2.8 1.4e-08 34.5 0.1 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ABX13514.1 - 4.1e-16 59.1 0.0 1.9e-06 28.4 0.0 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ABX13514.1 - 2.8e-15 54.8 3.5 0.00099 18.7 0.0 5.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 ABX13514.1 - 2.8e-14 52.3 0.0 0.00014 22.1 0.0 5.5 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ABX13514.1 - 1e-13 51.3 0.9 1.1e-05 25.6 0.1 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ABX13514.1 - 9e-13 47.3 4.6 0.00018 21.4 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ABX13514.1 - 7.6e-12 45.2 3.3 4.5e-06 26.6 0.1 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 ABX13514.1 - 8.8e-11 41.3 0.3 0.0047 16.8 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 ABX13514.1 - 9.2e-11 40.7 19.0 0.00099 18.7 0.1 6.4 4 1 2 6 6 6 3 Tetratricopeptide repeat NARP1 PF12569.3 ABX13514.1 - 1.7e-07 30.3 3.3 3.1e-07 29.5 0.4 2.2 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 ABX13514.1 - 4.6e-07 29.6 0.0 0.0026 17.5 0.0 3.1 2 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ABX13514.1 - 1.8e-06 27.7 6.6 5.5 6.9 0.1 5.2 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 ABX13514.1 - 1.5e-05 24.1 0.5 3.6e-05 22.9 0.3 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 ABX13514.1 - 3.8e-05 23.8 1.7 1.5 9.4 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat MIT PF04212.13 ABX13514.1 - 4.7e-05 23.1 5.7 0.74 9.7 0.2 3.9 2 1 2 4 4 4 2 MIT (microtubule interacting and transport) domain Cas_Cas02710 PF09670.5 ABX13514.1 - 0.0008 18.1 0.7 0.0015 17.2 0.3 1.5 1 1 0 1 1 1 1 CRISPR-associated protein (Cas_Cas02710) Rapsyn_N PF10579.4 ABX13514.1 - 0.0017 18.1 0.1 0.13 12.1 0.0 3.1 3 1 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_20 PF14561.1 ABX13514.1 - 0.0022 18.0 0.1 1.4 9.0 0.2 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 ABX13514.1 - 0.0022 18.3 0.0 0.0087 16.3 0.0 1.8 1 1 1 2 2 2 1 Bacterial transcriptional activator domain Coatomer_E PF04733.9 ABX13514.1 - 0.0029 16.8 3.8 0.23 10.6 0.5 2.2 1 1 1 2 2 2 2 Coatomer epsilon subunit Alkyl_sulf_dimr PF14863.1 ABX13514.1 - 0.0031 17.7 0.5 0.51 10.5 0.0 2.5 1 1 2 3 3 3 1 Alkyl sulfatase dimerisation Clathrin PF00637.15 ABX13514.1 - 0.011 15.3 11.2 0.052 13.1 5.7 2.5 1 1 1 2 2 2 0 Region in Clathrin and VPS PPTA PF01239.17 ABX13514.1 - 0.012 14.9 5.6 0.11 11.9 0.1 3.6 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat SPOB_a PF14689.1 ABX13514.1 - 0.3 10.6 4.5 40 3.8 0.1 4.0 4 1 1 5 5 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain Response_reg PF00072.19 ABX13515.1 - 2.4e-19 69.3 0.3 2.7e-19 69.2 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Pyr_redox PF00070.22 ABX13515.1 - 0.037 14.4 0.0 12 6.3 0.0 2.6 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ABX13515.1 - 0.13 12.2 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrmB PF01978.14 ABX13516.1 - 0.025 14.2 0.0 0.077 12.7 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HpcH_HpaI PF03328.9 ABX13517.1 - 8.7e-49 165.3 0.0 1.1e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 ABX13517.1 - 9.3e-17 60.8 0.9 1.6e-08 33.8 0.1 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.16 ABX13517.1 - 3.9e-05 22.4 1.1 5.5e-05 21.9 0.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain ADH_zinc_N PF00107.21 ABX13518.1 - 5.2e-29 100.4 0.0 9.6e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ABX13518.1 - 8.8e-22 76.9 0.1 1.5e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ABX13518.1 - 3.8e-16 60.1 0.0 7.3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 ABX13518.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ACP_syn_III_C PF08541.5 ABX13518.1 - 0.088 12.8 0.2 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal dsDNA_bind PF01984.15 ABX13519.1 - 1.9e-26 92.1 0.9 2.2e-26 91.9 0.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Ribosomal_S19e PF01090.14 ABX13520.1 - 2.1e-48 163.3 0.0 2.3e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e EMG1 PF03587.9 ABX13521.1 - 9.1e-43 145.9 0.2 1e-42 145.7 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF4373 PF14297.1 ABX13521.1 - 0.067 13.4 0.2 1.2 9.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4373) Glyco_hydro_42 PF02449.10 ABX13522.1 - 5e-05 22.5 0.0 0.0041 16.2 0.0 2.1 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.14 ABX13522.1 - 0.00017 21.0 0.1 0.0073 15.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 End_beta_barrel PF12195.3 ABX13522.1 - 0.11 12.3 0.1 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase Ribonuc_red_lgC PF02867.10 ABX13523.1 - 1.5e-152 508.9 0.0 2.7e-152 508.0 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 ABX13523.1 - 2.7e-32 110.3 0.0 6.6e-32 109.1 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 ABX13523.1 - 2.5e-23 82.3 2.0 4e-23 81.6 0.5 2.1 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 ABX13524.1 - 2.7e-23 81.8 0.0 4.2e-20 71.3 0.0 2.3 2 0 0 2 2 2 2 Anaerobic ribonucleoside-triphosphate reductase HTH_20 PF12840.2 ABX13524.1 - 7.5e-10 38.4 0.0 2.3e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain ATP-cone PF03477.11 ABX13524.1 - 1.3e-07 31.9 1.5 7.6e-07 29.4 0.0 3.0 3 0 0 3 3 3 1 ATP cone domain zf-ribbon_3 PF13248.1 ABX13525.1 - 0.00012 21.1 2.8 0.058 12.6 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 ABX13525.1 - 0.00015 21.0 2.7 0.048 13.1 0.2 2.2 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 ABX13525.1 - 0.0015 17.8 1.3 0.12 11.6 0.1 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding Chordopox_RPO7 PF05864.7 ABX13525.1 - 0.0021 18.1 2.0 0.035 14.1 0.4 2.1 1 1 1 2 2 2 2 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zf-DNA_Pol PF08996.5 ABX13525.1 - 0.0032 16.8 0.7 0.0032 16.8 0.5 1.0 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DZR PF12773.2 ABX13525.1 - 0.0038 16.9 1.9 0.0089 15.8 1.3 1.6 1 1 0 1 1 1 1 Double zinc ribbon zf-C4_Topoisom PF01396.14 ABX13525.1 - 0.0039 16.6 3.3 0.14 11.7 0.2 2.2 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger FANCL_C PF11793.3 ABX13525.1 - 0.007 16.3 1.4 0.039 13.9 0.9 1.9 1 1 1 2 2 2 1 FANCL C-terminal domain zinc_ribbon_5 PF13719.1 ABX13525.1 - 0.0076 15.8 3.0 0.23 11.1 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zf-LITAF-like PF10601.4 ABX13525.1 - 0.008 16.0 1.4 0.44 10.4 0.1 2.2 1 1 1 2 2 2 1 LITAF-like zinc ribbon domain Prok-RING_1 PF14446.1 ABX13525.1 - 0.0081 15.8 0.9 0.93 9.2 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zinc_ribbon_4 PF13717.1 ABX13525.1 - 0.0097 15.5 3.0 0.3 10.8 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zf-Di19 PF05605.7 ABX13525.1 - 0.011 15.8 0.4 1.5 9.0 0.0 2.0 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.14 ABX13525.1 - 0.013 15.1 0.4 0.018 14.7 0.3 1.3 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C2HC5 PF06221.8 ABX13525.1 - 0.017 14.8 2.1 0.19 11.4 0.1 2.0 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-IS66 PF13005.2 ABX13525.1 - 0.017 15.0 1.1 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Lar_restr_allev PF14354.1 ABX13525.1 - 0.019 15.2 0.4 0.029 14.6 0.3 1.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar LIM PF00412.17 ABX13525.1 - 0.021 14.8 0.1 0.034 14.2 0.1 1.4 1 1 0 1 1 1 0 LIM domain zf-TFIIB PF13453.1 ABX13525.1 - 0.024 13.8 0.6 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger Sgf11 PF08209.6 ABX13525.1 - 0.026 13.8 0.8 2.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF4428 PF14471.1 ABX13525.1 - 0.026 14.2 4.2 1.5 8.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Zn-ribbon_8 PF09723.5 ABX13525.1 - 0.03 14.2 3.4 0.27 11.2 2.4 2.0 1 1 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 ABX13525.1 - 0.033 13.8 1.9 0.056 13.1 1.3 1.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 ABX13525.1 - 0.042 14.1 2.6 3.5 8.1 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF329 PF03884.9 ABX13525.1 - 0.055 13.0 0.8 2.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-ISL3 PF14690.1 ABX13525.1 - 0.062 13.3 1.1 6.4 6.8 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DiS_P_DiS PF06750.8 ABX13525.1 - 0.064 13.0 0.9 0.43 10.3 0.6 1.9 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DUF983 PF06170.7 ABX13525.1 - 0.073 13.1 0.1 8.4 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zf-C2H2_4 PF13894.1 ABX13525.1 - 0.074 13.4 0.3 13 6.4 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Elf1 PF05129.8 ABX13525.1 - 0.074 12.7 1.5 2 8.1 0.1 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.1 ABX13525.1 - 0.076 13.3 0.7 2.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain DNA_RNApol_7kD PF03604.8 ABX13525.1 - 0.08 12.4 1.3 2.1 7.8 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.2 ABX13525.1 - 0.1 12.4 1.8 2.8 7.8 0.0 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-dskA_traR PF01258.12 ABX13525.1 - 0.1 12.3 1.4 5.9 6.7 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger YhfH PF14149.1 ABX13525.1 - 0.12 12.1 5.9 2.8 7.7 0.8 2.2 2 0 0 2 2 2 0 YhfH-like protein Nudix_N_2 PF14803.1 ABX13525.1 - 0.15 11.7 1.1 3.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Nudix N-terminal TFIIS_C PF01096.13 ABX13525.1 - 0.16 11.6 3.1 5.6 6.6 0.1 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Ogr_Delta PF04606.7 ABX13525.1 - 0.16 11.6 0.6 2.8 7.6 0.1 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DNA_ligase_ZBD PF03119.11 ABX13525.1 - 0.18 11.5 0.4 0.18 11.5 0.3 1.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc-ribbons_6 PF07191.7 ABX13525.1 - 0.2 11.4 1.4 6.1 6.7 0.1 2.1 1 1 0 2 2 2 0 zinc-ribbons zf-NADH-PPase PF09297.6 ABX13525.1 - 0.28 10.7 4.4 4.8 6.7 0.2 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain T4_baseplate PF12322.3 ABX13525.1 - 0.46 9.6 2.5 5 6.3 0.1 2.0 1 1 1 2 2 2 0 T4 bacteriophage base plate protein Ribosomal_S27e PF01667.12 ABX13525.1 - 0.53 9.8 2.6 8.7 5.9 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 Cript PF10235.4 ABX13525.1 - 0.92 9.9 3.8 37 4.7 0.5 1.8 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT ADK_lid PF05191.9 ABX13525.1 - 0.94 9.1 5.1 20 4.9 0.5 2.1 1 1 1 2 2 2 0 Adenylate kinase, active site lid Zn_ribbon_recom PF13408.1 ABX13525.1 - 1 9.6 4.7 5 7.4 0.6 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain OrfB_Zn_ribbon PF07282.6 ABX13525.1 - 1.1 8.9 5.2 2.1 8.0 0.4 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain DUF35 PF01796.12 ABX13526.1 - 1.7e-08 34.5 0.1 2.3e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain DUF35_N PF12172.3 ABX13526.1 - 0.00021 21.1 0.2 0.00034 20.4 0.1 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.1 ABX13526.1 - 0.00046 19.5 3.8 0.00089 18.6 2.6 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 ABX13526.1 - 0.0081 15.3 0.8 0.014 14.5 0.6 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 ABX13526.1 - 0.009 15.8 1.3 0.014 15.2 0.9 1.3 1 0 0 1 1 1 1 Double zinc ribbon PHF5 PF03660.9 ABX13526.1 - 0.12 12.4 0.5 0.15 12.1 0.3 1.2 1 0 0 1 1 1 0 PHF5-like protein RNA_POL_M_15KD PF02150.11 ABX13526.1 - 0.17 11.5 1.7 13 5.6 0.3 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.7 ABX13526.1 - 0.35 10.2 2.2 18 4.7 0.0 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding RNHCP PF12647.2 ABX13526.1 - 0.36 10.6 1.7 0.47 10.3 0.4 1.7 1 1 1 2 2 2 0 RNHCP domain Nudix_N_2 PF14803.1 ABX13526.1 - 0.37 10.4 3.2 4.5 7.0 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal GFA PF04828.9 ABX13526.1 - 0.4 10.6 2.8 2.7 8.0 1.9 2.1 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DUF164 PF02591.10 ABX13526.1 - 0.62 9.9 2.6 0.59 10.0 0.1 1.9 2 0 0 2 2 2 0 Putative zinc ribbon domain DNA_RNApol_7kD PF03604.8 ABX13526.1 - 3.1 7.3 6.0 16 5.0 0.6 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Thiolase_C PF02803.13 ABX13527.1 - 8.5e-12 44.5 1.3 4e-10 39.1 0.0 3.2 2 2 2 4 4 4 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 ABX13527.1 - 7.7e-08 31.6 0.0 3.2e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 ABX13527.1 - 0.00022 20.7 0.2 0.069 12.6 0.0 2.8 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 ABX13527.1 - 0.034 13.8 0.1 2 8.1 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.17 ABX13527.1 - 0.11 12.3 2.0 1.4 8.7 0.0 3.2 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain zf-C4_Topoisom PF01396.14 ABX13528.1 - 6.5e-07 28.7 9.8 3e-06 26.6 0.7 2.8 2 1 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_recom PF13408.1 ABX13528.1 - 0.061 13.5 7.6 0.16 12.2 0.4 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Ogr_Delta PF04606.7 ABX13528.1 - 0.16 11.6 14.3 0.43 10.2 1.1 3.6 3 2 0 3 3 3 0 Ogr/Delta-like zinc finger CN_hydrolase PF00795.17 ABX13529.1 - 2.4e-32 111.8 0.0 3.1e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Tautomerase PF01361.16 ABX13530.1 - 5.5e-14 51.5 0.0 5.8e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.1 ABX13530.1 - 1.5e-08 34.5 0.0 1.5e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme DUF1904 PF08921.6 ABX13530.1 - 0.0075 16.2 0.0 0.0075 16.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1904) Tautomerase_3 PF14832.1 ABX13530.1 - 0.018 15.0 0.0 0.019 14.9 0.0 1.0 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme Rhomboid PF01694.17 ABX13531.1 - 5.4e-33 114.0 20.2 5.4e-33 114.0 14.0 1.5 2 0 0 2 2 2 1 Rhomboid family Copper-bind PF00127.15 ABX13533.1 - 1.3e-06 28.5 0.0 4.9e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 ABX13533.1 - 0.00012 21.9 0.0 0.00081 19.2 0.0 2.4 2 0 0 2 2 2 1 Cupredoxin-like domain DUF87 PF01935.12 ABX13535.1 - 0.054 13.3 1.7 0.98 9.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Ets PF00178.17 ABX13536.1 - 0.044 13.9 0.4 0.091 12.9 0.3 1.5 1 0 0 1 1 1 0 Ets-domain DUF4296 PF14129.1 ABX13536.1 - 0.1 12.7 2.5 5.6 7.1 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) VWA_2 PF13519.1 ABX13537.1 - 2.5e-32 112.3 0.1 3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ABX13537.1 - 4.2e-21 75.4 0.3 5.6e-21 75.0 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain BatA PF07584.6 ABX13537.1 - 4.5e-07 29.9 0.1 4.5e-07 29.9 0.1 1.7 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal Ssl1 PF04056.9 ABX13537.1 - 0.00018 21.1 0.0 0.0081 15.7 0.0 2.1 2 0 0 2 2 2 1 Ssl1-like VWA_3 PF13768.1 ABX13537.1 - 0.00024 20.8 0.0 0.00044 19.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 ABX13537.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein PTPLA PF04387.9 ABX13537.1 - 0.035 13.5 1.4 0.091 12.1 0.2 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase-like protein, PTPLA DUF1194 PF06707.6 ABX13537.1 - 0.04 12.8 0.1 0.21 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) vWA-TerF-like PF10138.4 ABX13537.1 - 0.041 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus DUF58 PF01882.13 ABX13538.1 - 7.1e-23 80.5 0.0 1.2e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF58 VWA_2 PF13519.1 ABX13538.1 - 0.00012 22.2 0.0 0.00014 21.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_beta PF00362.13 ABX13538.1 - 0.046 12.6 0.1 0.16 10.8 0.2 1.7 1 1 1 2 2 2 0 Integrin, beta chain AAA_3 PF07726.6 ABX13539.1 - 6.9e-63 210.1 0.1 1.2e-62 209.2 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ABX13539.1 - 2.9e-11 43.2 0.0 6.3e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.18 ABX13539.1 - 4.6e-07 28.9 0.4 1.7e-06 27.1 0.3 1.9 1 1 0 1 1 1 1 MCM2/3/5 family Sigma54_activat PF00158.21 ABX13539.1 - 6.2e-05 22.5 0.0 0.00018 21.0 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.7 ABX13539.1 - 0.00053 19.1 0.4 0.0032 16.5 0.2 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 ABX13539.1 - 0.0027 17.9 0.2 0.014 15.6 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 ABX13539.1 - 0.0043 16.2 2.1 0.047 12.8 0.1 2.6 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI Lgl_C PF08596.5 ABX13539.1 - 0.06 11.7 0.1 0.088 11.2 0.1 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal DUF2393 PF09624.5 ABX13540.1 - 0.84 9.1 7.4 3.4 7.1 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2393) HTH_24 PF13412.1 ABX13541.1 - 4.3e-14 51.6 0.1 6.5e-07 28.6 0.1 2.6 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 ABX13541.1 - 1e-11 44.2 0.1 7.9e-07 28.6 0.0 2.6 2 1 0 2 2 2 2 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 ABX13541.1 - 2e-08 33.7 0.1 9.8e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 MarR family HTH_20 PF12840.2 ABX13541.1 - 2.9e-08 33.3 0.0 8e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain TrmB PF01978.14 ABX13541.1 - 3.2e-08 33.1 0.1 0.00024 20.7 0.1 2.3 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 ABX13541.1 - 3.4e-07 29.8 0.0 0.0029 17.2 0.0 2.3 2 0 0 2 2 2 2 MarR family HTH_45 PF14947.1 ABX13541.1 - 7e-07 28.9 0.0 0.039 13.7 0.0 2.2 2 0 0 2 2 2 2 Winged helix-turn-helix Rrf2 PF02082.15 ABX13541.1 - 4.7e-06 26.6 0.1 0.018 15.1 0.0 2.3 2 0 0 2 2 2 2 Transcriptional regulator FeoC PF09012.5 ABX13541.1 - 9.4e-06 25.2 0.0 0.071 12.8 0.0 2.2 2 0 0 2 2 2 2 FeoC like transcriptional regulator HTH_IclR PF09339.5 ABX13541.1 - 1.3e-05 24.6 0.0 0.026 14.0 0.0 2.2 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_34 PF13601.1 ABX13541.1 - 4.6e-05 23.3 0.0 0.078 13.0 0.0 2.2 2 0 0 2 2 2 2 Winged helix DNA-binding domain HTH_29 PF13551.1 ABX13541.1 - 0.00033 20.7 0.0 0.1 12.7 0.0 2.2 1 1 1 2 2 2 1 Winged helix-turn helix DUF2250 PF10007.4 ABX13541.1 - 0.00071 19.4 0.3 0.17 11.7 0.2 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) LexA_DNA_bind PF01726.11 ABX13541.1 - 0.00077 18.9 0.1 0.056 13.0 0.0 2.6 2 1 0 2 2 2 1 LexA DNA binding domain HTH_27 PF13463.1 ABX13541.1 - 0.002 18.4 0.1 0.19 12.1 0.0 2.7 2 1 0 2 2 2 1 Winged helix DNA-binding domain DUF4393 PF14337.1 ABX13541.1 - 0.0027 17.1 0.1 0.18 11.1 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4393) RPA_C PF08784.6 ABX13541.1 - 0.0045 17.3 0.0 4.2 7.8 0.0 2.3 2 0 0 2 2 2 2 Replication protein A C terminal Penicillinase_R PF03965.11 ABX13541.1 - 0.0059 16.6 0.0 2 8.4 0.1 2.6 1 1 1 2 2 2 1 Penicillinase repressor Fe_dep_repress PF01325.14 ABX13541.1 - 0.0082 16.0 0.2 0.04 13.8 0.0 2.0 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.1 ABX13541.1 - 0.015 15.0 0.1 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain B-block_TFIIIC PF04182.7 ABX13541.1 - 0.018 14.8 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC HTH_40 PF14493.1 ABX13541.1 - 0.023 14.9 0.1 0.89 9.8 0.0 2.4 1 1 2 3 3 3 0 Helix-turn-helix domain Cdc6_C PF09079.6 ABX13541.1 - 0.041 13.5 0.0 6.5 6.5 0.0 2.2 2 0 0 2 2 2 0 CDC6, C terminal PCI PF01399.22 ABX13541.1 - 0.061 13.6 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 PCI domain RP-C PF03428.8 ABX13541.1 - 0.077 12.4 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Replication protein C N-terminal domain RNA_pol_Rpc34 PF05158.7 ABX13541.1 - 0.079 12.1 0.4 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase Rpc34 subunit RICH PF05062.7 ABX13541.1 - 0.13 12.4 0.5 0.25 11.4 0.3 1.5 1 0 0 1 1 1 0 RICH domain NVEALA PF14055.1 ABX13542.1 - 0.063 12.9 0.0 0.063 12.9 0.0 1.6 2 0 0 2 2 2 0 NVEALA protein PTS_EIIC_2 PF13303.1 ABX13542.1 - 0.15 10.8 4.4 0.17 10.7 3.0 1.0 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF898 PF05987.8 ABX13542.1 - 0.32 9.8 8.7 0.89 8.3 6.0 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) EcsB PF05975.7 ABX13542.1 - 0.4 9.1 7.8 0.41 9.0 5.4 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB YqhR PF11085.3 ABX13542.1 - 0.86 9.1 3.6 1.1 8.7 2.5 1.4 1 1 0 1 1 1 0 Conserved membrane protein YqhR Tetraspannin PF00335.15 ABX13542.1 - 7.9 5.6 6.8 13 5.0 4.7 1.3 1 0 0 1 1 1 0 Tetraspanin family GOLD_2 PF13897.1 ABX13543.1 - 0.37 11.0 6.5 0.39 10.9 0.1 3.1 3 1 0 3 3 3 0 Golgi-dynamics membrane-trafficking Cupredoxin_1 PF13473.1 ABX13546.1 - 3.1e-05 23.8 0.0 0.00019 21.2 0.0 2.2 2 1 0 2 2 2 1 Cupredoxin-like domain Copper-bind PF00127.15 ABX13546.1 - 0.029 14.5 0.1 0.09 13.0 0.0 1.9 2 1 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family FlxA PF14282.1 ABX13547.1 - 0.13 12.1 0.1 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 FlxA-like protein SGL PF08450.7 ABX13548.1 - 1.2e-14 54.2 0.7 0.025 13.9 0.0 5.1 1 1 4 5 5 5 4 SMP-30/Gluconolaconase/LRE-like region CopC PF04234.7 ABX13548.1 - 6.8e-13 49.0 0.1 2.6e-12 47.1 0.0 2.1 3 0 0 3 3 3 1 CopC domain CopD PF05425.8 ABX13548.1 - 2.9e-12 46.7 0.6 2.9e-12 46.7 0.4 2.4 3 0 0 3 3 3 1 Copper resistance protein D Reg_prop PF07494.6 ABX13548.1 - 0.00048 19.8 14.9 4.7 7.5 0.0 7.4 8 0 0 8 8 8 2 Two component regulator propeller YtkA PF13115.1 ABX13548.1 - 0.052 13.9 0.0 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 YtkA-like PPC PF04151.10 ABX13548.1 - 0.071 14.0 3.8 0.1 13.5 0.8 2.6 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Big_3_4 PF13754.1 ABX13548.1 - 0.11 12.8 0.2 10 6.5 0.0 2.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF4149 PF13664.1 ABX13548.1 - 2.1 8.4 14.2 0.018 15.0 1.8 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) ABC-3 PF00950.12 ABX13549.1 - 2.4e-63 213.8 37.3 2.7e-63 213.6 25.9 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.13 ABX13549.1 - 5.1e-06 25.5 33.8 1.2e-05 24.3 23.0 1.8 1 1 0 1 1 1 1 FecCD transport family ABC_tran PF00005.22 ABX13550.1 - 1.1e-33 116.3 0.0 3.5e-33 114.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 ABX13550.1 - 4.6e-13 49.7 5.1 1.6e-11 44.7 3.5 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 ABX13550.1 - 3e-06 26.6 1.3 6.1e-05 22.3 0.9 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ABX13550.1 - 9.4e-06 26.0 3.9 1.8e-05 25.1 2.7 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ABX13550.1 - 2.5e-05 23.7 0.0 4.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 ABX13550.1 - 6e-05 22.5 0.3 0.13 11.6 0.0 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein AAA_15 PF13175.1 ABX13550.1 - 0.00014 21.0 6.4 0.03 13.3 1.6 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_13 PF13166.1 ABX13550.1 - 0.001 17.6 2.2 0.21 10.0 0.2 2.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 ABX13550.1 - 0.0042 16.2 0.0 0.0088 15.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ABX13550.1 - 0.0044 16.9 0.1 0.0081 16.1 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 ABX13550.1 - 0.0044 16.8 0.0 0.13 12.1 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 ABX13550.1 - 0.025 14.0 0.3 0.65 9.3 0.1 2.2 1 1 1 2 2 2 0 AAA-like domain AAA_22 PF13401.1 ABX13550.1 - 0.035 14.2 0.4 0.14 12.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ABX13550.1 - 0.055 13.4 0.1 0.35 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 ABX13550.1 - 0.086 12.7 0.7 2.2 8.2 0.4 2.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ABX13550.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ABX13550.1 - 0.12 13.2 0.8 2.2 9.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain TroA PF01297.12 ABX13551.1 - 2.4e-80 269.4 1.7 2.8e-80 269.2 1.2 1.0 1 0 0 1 1 1 1 Periplasmic solute binding protein family NikR_C PF08753.6 ABX13552.1 - 9.7e-11 41.4 2.4 1.4e-10 40.8 1.7 1.3 1 0 0 1 1 1 1 NikR C terminal nickel binding domain RHH_1 PF01402.16 ABX13552.1 - 0.00041 20.1 0.1 0.0007 19.3 0.1 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family DUF2191 PF09957.4 ABX13552.1 - 0.0025 17.5 0.0 0.0057 16.4 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2191) RRF PF01765.14 ABX13553.1 - 0.013 14.9 0.5 0.015 14.7 0.3 1.1 1 0 0 1 1 1 0 Ribosome recycling factor DUF1980 PF09323.5 ABX13553.1 - 0.016 14.9 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Glyco_tranf_2_4 PF13704.1 ABX13553.1 - 0.056 13.7 0.0 0.071 13.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2232 PF09991.4 ABX13553.1 - 0.081 11.9 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4546 PF15079.1 ABX13553.1 - 0.082 12.0 3.7 0.095 11.8 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) HAMP PF00672.20 ABX13553.1 - 0.12 12.5 3.6 3.4 7.9 0.1 2.1 2 0 0 2 2 2 0 HAMP domain DUF4252 PF14060.1 ABX13553.1 - 0.22 11.0 2.4 0.13 11.7 0.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4252) Thioredoxin_4 PF13462.1 ABX13554.1 - 5.9e-38 130.4 0.0 8.3e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 ABX13554.1 - 3.8e-19 69.0 0.1 1.7e-12 47.2 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 ABX13554.1 - 6.7e-07 29.4 0.0 2.4e-06 27.6 0.0 1.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 ABX13554.1 - 0.0002 20.9 0.1 0.00053 19.5 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin DUF929 PF06053.6 ABX13554.1 - 0.016 14.3 0.1 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) zf-H2C2_2 PF13465.1 ABX13554.1 - 0.23 11.8 1.2 0.5 10.7 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger double domain SecE PF00584.15 ABX13554.1 - 0.93 9.1 4.0 1.7 8.2 2.7 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Usp PF00582.21 ABX13555.1 - 7e-28 97.5 0.0 8.3e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family SBP_bac_5 PF00496.17 ABX13555.1 - 0.13 11.0 0.1 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle BNR_2 PF13088.1 ABX13556.1 - 1.2e-06 28.0 3.8 0.018 14.3 0.0 3.1 2 1 0 3 3 3 3 BNR repeat-like domain PSII_BNR PF14870.1 ABX13556.1 - 1.4e-06 27.5 8.9 0.0059 15.6 0.2 4.1 1 1 3 4 4 4 2 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 ABX13556.1 - 8.5e-05 21.8 19.2 0.29 11.1 0.1 5.8 5 0 0 5 5 5 3 BNR/Asp-box repeat SGL PF08450.7 ABX13556.1 - 0.0042 16.5 0.1 0.052 12.9 0.0 2.4 1 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region HxlR PF01638.12 ABX13557.1 - 1.7e-23 82.0 0.0 2.2e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.9 ABX13557.1 - 3.3e-05 23.5 0.1 5.1e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.17 ABX13557.1 - 0.00067 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.1 ABX13557.1 - 0.00093 18.5 0.1 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_45 PF14947.1 ABX13557.1 - 0.0065 16.2 0.2 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_20 PF12840.2 ABX13557.1 - 0.02 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_12 PF08461.5 ABX13557.1 - 0.029 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF693 PF05113.8 ABX13557.1 - 0.032 13.1 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF693) Pox_A51 PF04948.8 ABX13557.1 - 0.079 11.6 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A51 protein HTH_Crp_2 PF13545.1 ABX13557.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain Zip PF02535.17 ABX13558.1 - 4.6e-06 25.8 16.2 4.6e-06 25.8 11.2 2.5 1 1 1 2 2 2 2 ZIP Zinc transporter Cu-oxidase_3 PF07732.10 ABX13559.1 - 3.2e-25 88.1 3.1 1.2e-20 73.3 0.2 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 ABX13559.1 - 5.1e-20 71.3 7.3 1.4e-08 34.3 0.1 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 ABX13559.1 - 0.097 12.5 0.0 19 5.1 0.0 2.8 3 0 0 3 3 3 0 Cupredoxin-like domain Fe_dep_repress PF01325.14 ABX13560.1 - 1.1e-21 76.4 0.2 2.3e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.10 ABX13560.1 - 2.6e-13 49.4 0.0 5.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain MarR_2 PF12802.2 ABX13560.1 - 1.4e-05 24.7 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.17 ABX13560.1 - 7.9e-05 22.2 0.0 0.00021 20.9 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 ABX13560.1 - 0.00014 22.0 0.0 0.00072 19.8 0.0 2.1 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_45 PF14947.1 ABX13560.1 - 0.00052 19.7 0.1 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix LexA_DNA_bind PF01726.11 ABX13560.1 - 0.0012 18.3 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 LexA DNA binding domain DUF2250 PF10007.4 ABX13560.1 - 0.011 15.6 1.8 0.046 13.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_24 PF13412.1 ABX13560.1 - 0.011 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.14 ABX13560.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 ABX13560.1 - 0.044 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_Crp_2 PF13545.1 ABX13560.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_6 PF01418.12 ABX13560.1 - 0.12 12.1 0.0 0.43 10.3 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family DUF948 PF06103.6 ABX13560.1 - 0.15 11.9 0.4 1.4 8.8 0.0 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) LAGLIDADG_3 PF14528.1 ABX13560.1 - 0.16 12.2 2.2 2.9 8.1 0.1 2.9 2 2 0 2 2 2 0 LAGLIDADG-like domain DUF1154 PF06631.6 ABX13560.1 - 0.33 10.6 7.6 1.2 8.8 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Copper-bind PF00127.15 ABX13561.1 - 1.4e-08 34.8 0.0 2.5e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 ABX13561.1 - 0.00012 21.9 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain Kelch_1 PF01344.20 ABX13562.1 - 2.2e-49 164.7 4.1 1.8e-10 40.2 0.0 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 ABX13562.1 - 1.1e-40 136.1 9.2 2.6e-09 36.8 0.1 6.9 3 2 4 7 7 7 6 Kelch motif Kelch_2 PF07646.10 ABX13562.1 - 9e-32 107.6 0.5 8.7e-06 25.2 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 ABX13562.1 - 2e-29 101.0 8.7 6.6e-07 29.3 0.0 7.2 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 ABX13562.1 - 2.4e-28 97.5 1.3 7e-05 22.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 ABX13562.1 - 2e-25 88.2 8.1 5.5e-06 26.0 0.0 6.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Rax2 PF12768.2 ABX13562.1 - 0.0001 21.6 0.0 0.0056 15.9 0.0 2.2 2 0 0 2 2 2 1 Cortical protein marker for cell polarity PQQ_3 PF13570.1 ABX13562.1 - 0.001 19.2 0.3 11 6.4 0.0 4.4 5 0 0 5 5 5 1 PQQ-like domain Head_binding PF09008.5 ABX13562.1 - 0.0014 18.6 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Head binding Cu-oxidase_3 PF07732.10 ABX13563.1 - 4e-11 42.6 1.9 3.5e-09 36.4 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 ABX13563.1 - 0.00053 19.5 1.0 0.079 12.4 0.2 2.8 2 1 0 2 2 2 2 Multicopper oxidase GHL12 PF14882.1 ABX13564.1 - 8.6e-14 51.3 11.2 0.00048 20.1 0.2 3.6 3 0 0 3 3 3 3 Hypothetical glycosyl hydrolase 12 DUF2717 PF10911.3 ABX13564.1 - 0.00082 18.8 0.1 3.4 7.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2717) Alpha-mann_mid PF09261.6 ABX13564.1 - 0.17 12.1 0.5 28 5.0 0.0 2.6 2 1 0 2 2 2 0 Alpha mannosidase, middle domain DUF4131 PF13567.1 ABX13565.1 - 0.0074 15.7 2.6 0.088 12.2 0.1 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4131) UPF0697 PF15117.1 ABX13565.1 - 0.34 10.7 1.8 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 SecE PF00584.15 ABX13565.1 - 10 5.8 8.5 14 5.3 0.2 3.2 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex Thioredoxin_4 PF13462.1 ABX13566.1 - 5.7e-42 143.4 0.1 7.4e-42 143.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 ABX13566.1 - 5.1e-19 68.5 0.2 5.1e-11 42.4 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 ABX13566.1 - 9.4e-08 32.2 0.1 2.7e-07 30.7 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 ABX13566.1 - 0.0068 15.9 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin DUF929 PF06053.6 ABX13566.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) SGL PF08450.7 ABX13567.1 - 4e-09 36.2 0.6 0.32 10.3 0.1 4.6 2 2 2 4 4 4 4 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 ABX13567.1 - 0.00097 18.9 1.7 0.031 14.2 0.1 3.5 4 0 0 4 4 4 1 NHL repeat Reg_prop PF07494.6 ABX13567.1 - 0.0039 17.0 7.1 43 4.6 0.1 6.1 6 0 0 6 6 6 0 Two component regulator propeller FixG_C PF11614.3 ABX13567.1 - 0.065 13.3 0.7 0.19 11.8 0.5 1.8 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase NVEALA PF14055.1 ABX13568.1 - 0.12 12.1 0.5 0.21 11.3 0.3 1.4 1 0 0 1 1 1 0 NVEALA protein DUF3139 PF11337.3 ABX13568.1 - 0.35 11.1 3.0 0.66 10.2 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) Trypsin_2 PF13365.1 ABX13569.1 - 8.2e-22 77.4 0.9 1.3e-21 76.7 0.6 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 ABX13569.1 - 6.1e-13 48.4 2.1 1.1e-12 47.6 0.7 2.1 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.21 ABX13569.1 - 8.8e-13 48.3 0.8 2.4e-12 46.9 0.6 1.7 1 1 0 1 1 1 1 Trypsin Peptidase_S29 PF02907.10 ABX13569.1 - 0.00036 20.0 0.1 0.00062 19.3 0.0 1.4 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S32 PF05579.8 ABX13569.1 - 0.072 12.0 4.9 1.4 7.8 0.1 2.4 2 1 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.4 ABX13569.1 - 0.077 11.4 2.5 0.12 10.7 0.2 1.9 2 0 0 2 2 2 0 Peptidase S46 PDZ PF00595.19 ABX13569.1 - 0.23 11.6 6.3 7.4 6.8 0.5 3.2 2 1 0 3 3 3 0 PDZ domain (Also known as DHR or GLGF) HTH_24 PF13412.1 ABX13570.1 - 1.5e-13 49.8 0.3 2.2e-06 26.9 0.0 3.4 3 0 0 3 3 3 3 Winged helix-turn-helix DNA-binding TrmB PF01978.14 ABX13570.1 - 6.4e-12 45.0 0.1 0.00045 19.8 0.0 3.5 3 1 1 4 4 4 2 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 ABX13570.1 - 2.9e-09 36.3 0.0 0.00027 20.4 0.0 3.2 3 0 0 3 3 3 2 IclR helix-turn-helix domain HTH_20 PF12840.2 ABX13570.1 - 6e-09 35.5 0.0 0.0077 16.0 0.0 3.2 3 0 0 3 3 3 3 Helix-turn-helix domain HTH_5 PF01022.15 ABX13570.1 - 1.4e-07 31.0 0.1 0.25 11.0 0.0 3.3 3 0 0 3 3 3 3 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 ABX13570.1 - 1.7e-07 30.8 0.0 0.0041 16.7 0.0 2.6 3 0 0 3 3 3 2 MarR family MarR PF01047.17 ABX13570.1 - 2.3e-06 27.2 0.6 0.52 10.0 0.0 3.4 3 0 0 3 3 3 2 MarR family HTH_34 PF13601.1 ABX13570.1 - 0.0013 18.7 0.1 6.1 6.9 0.0 3.1 3 0 0 3 3 3 2 Winged helix DNA-binding domain HTH_27 PF13463.1 ABX13570.1 - 0.0068 16.7 0.1 0.68 10.3 0.0 2.5 2 0 0 2 2 2 1 Winged helix DNA-binding domain FUR PF01475.14 ABX13570.1 - 0.016 15.1 0.1 0.091 12.6 0.0 2.1 2 0 0 2 2 2 0 Ferric uptake regulator family DUF4423 PF14394.1 ABX13570.1 - 0.016 14.7 0.1 0.51 9.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Rrf2 PF02082.15 ABX13570.1 - 0.017 15.2 0.3 17 5.5 0.0 3.1 3 0 0 3 3 3 0 Transcriptional regulator HTH_11 PF08279.7 ABX13570.1 - 0.046 13.3 0.1 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 HTH domain HTH_36 PF13730.1 ABX13570.1 - 0.072 13.2 1.3 6.8 6.8 0.0 3.2 3 1 1 4 4 4 0 Helix-turn-helix domain DUF742 PF05331.6 ABX13570.1 - 0.077 12.6 0.0 0.43 10.2 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF742) DUF998 PF06197.8 ABX13571.1 - 0.0038 16.5 2.5 0.0057 15.9 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Cas1_AcylT PF07779.7 ABX13571.1 - 0.01 14.3 2.3 0.014 13.9 1.6 1.1 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p Sugar_transport PF06800.7 ABX13571.1 - 0.035 13.1 2.1 0.047 12.7 1.4 1.3 1 1 0 1 1 1 0 Sugar transport protein 7TMR-DISM_7TM PF07695.6 ABX13571.1 - 0.051 13.2 11.8 0.093 12.3 8.2 1.4 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF3290 PF11694.3 ABX13571.1 - 0.13 11.9 3.3 0.48 10.1 0.0 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3290) YfhO PF09586.5 ABX13571.1 - 0.22 9.5 4.2 0.26 9.2 2.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Bax1-I PF01027.15 ABX13571.1 - 0.97 8.9 11.5 1.7 8.1 8.0 1.4 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Glucos_trans_II PF14264.1 ABX13571.1 - 1.1 8.1 11.7 2.2 7.1 8.1 1.5 1 1 0 1 1 1 0 Glucosyl transferase GtrII Peptidase_U4 PF03419.8 ABX13571.1 - 1.2 8.0 7.2 1.5 7.7 5.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Tmemb_18A PF09771.4 ABX13571.1 - 5.3 7.0 6.6 1.5 8.7 2.1 1.8 1 1 1 2 2 2 0 Transmembrane protein 188 Abi PF02517.11 ABX13571.1 - 6.2 7.0 6.7 4.8 7.3 0.4 2.3 1 1 1 2 2 2 0 CAAX protease self-immunity NfeD PF01957.13 ABX13571.1 - 7.8 6.6 6.6 1.1 9.4 0.4 2.0 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding hSac2 PF12456.3 ABX13573.1 - 0.056 12.8 0.1 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 Inositol phosphatase Copper-bind PF00127.15 ABX13574.1 - 2.6e-07 30.7 0.0 5.8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Ion_trans_N PF08412.5 ABX13574.1 - 0.033 13.5 0.0 0.082 12.2 0.0 1.7 1 0 0 1 1 1 0 Ion transport protein N-terminal Cupredoxin_1 PF13473.1 ABX13574.1 - 0.075 12.9 0.0 0.55 10.1 0.0 2.4 1 1 0 1 1 1 0 Cupredoxin-like domain DUF2603 PF10788.4 ABX13575.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) EamA PF00892.15 ABX13576.1 - 1.4e-35 122.0 39.1 1.9e-18 66.6 9.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 ABX13576.1 - 4.4e-11 42.9 30.8 1.1e-06 28.8 7.5 3.0 2 2 1 3 3 3 2 Multidrug resistance efflux transporter TCR_zetazeta PF11628.3 ABX13576.1 - 0.11 12.0 6.4 19 4.8 0.2 3.6 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 zeta chain TPT PF03151.11 ABX13576.1 - 0.39 10.3 31.4 3.5 7.2 8.5 3.3 2 2 0 2 2 2 0 Triose-phosphate Transporter family UPF0546 PF10639.4 ABX13576.1 - 0.72 9.6 13.1 1.9 8.3 1.5 2.7 2 1 0 2 2 2 0 Uncharacterised protein family UPF0546 UPF0060 PF02694.10 ABX13577.1 - 3.3e-40 136.4 8.9 3.8e-40 136.2 6.2 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family EamA PF00892.15 ABX13577.1 - 0.00041 20.3 11.9 0.0011 18.9 8.3 1.7 1 1 0 1 1 1 1 EamA-like transporter family Polysacc_synt PF01943.12 ABX13577.1 - 0.0051 16.1 1.2 0.0051 16.1 0.8 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein EmrE PF13536.1 ABX13577.1 - 0.022 14.9 6.3 0.031 14.4 4.4 1.2 1 0 0 1 1 1 0 Multidrug resistance efflux transporter 7TMR-DISM_7TM PF07695.6 ABX13577.1 - 0.067 12.8 9.2 0.28 10.8 6.7 1.4 1 1 0 1 1 1 0 7TM diverse intracellular signalling QCR10 PF09796.4 ABX13577.1 - 0.082 12.5 0.8 0.17 11.5 0.4 1.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) MFS_1 PF07690.11 ABX13577.1 - 0.14 10.7 12.8 1.1 7.8 8.9 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily Multi_Drug_Res PF00893.14 ABX13577.1 - 0.43 11.0 5.0 0.4 11.1 2.8 1.4 1 1 0 1 1 1 0 Small Multidrug Resistance protein DUF4345 PF14248.1 ABX13577.1 - 1.2 8.5 7.7 2.1 7.8 2.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4345) YrhC PF14143.1 ABX13577.1 - 2.6 8.0 4.7 0.54 10.2 0.6 1.8 2 0 0 2 2 2 0 YrhC-like protein DUF3611 PF12263.3 ABX13577.1 - 4.9 6.4 6.6 10 5.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) UPF0060 PF02694.10 ABX13578.1 - 5.7e-37 126.0 7.5 6.4e-37 125.8 5.2 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family EmrE PF13536.1 ABX13578.1 - 5.4e-06 26.5 3.2 1.1e-05 25.6 2.2 1.4 1 1 0 1 1 1 1 Multidrug resistance efflux transporter EamA PF00892.15 ABX13578.1 - 0.0002 21.4 3.2 0.00035 20.6 2.2 1.4 1 1 0 1 1 1 1 EamA-like transporter family MFS_1 PF07690.11 ABX13578.1 - 0.00027 19.7 4.1 0.0037 16.0 0.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TMR-DISM_7TM PF07695.6 ABX13578.1 - 0.0033 17.1 4.3 0.0089 15.7 3.0 1.7 1 1 0 1 1 1 1 7TM diverse intracellular signalling PMT_2 PF13231.1 ABX13578.1 - 0.05 13.4 1.8 0.4 10.5 0.1 2.0 1 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF3147 PF11345.3 ABX13578.1 - 0.051 13.5 0.4 0.085 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) Multi_Drug_Res PF00893.14 ABX13578.1 - 0.07 13.6 1.5 0.085 13.3 0.8 1.4 1 1 0 1 1 1 0 Small Multidrug Resistance protein Acyl_transf_3 PF01757.17 ABX13578.1 - 0.076 11.8 5.8 0.096 11.5 4.0 1.1 1 0 0 1 1 1 0 Acyltransferase family COX14 PF14880.1 ABX13578.1 - 1.9 8.1 7.1 0.32 10.6 0.5 2.5 2 1 0 2 2 2 0 Cytochrome oxidase c assembly PGPGW PF09656.5 ABX13578.1 - 2.1 7.7 6.2 5.5 6.3 0.6 2.5 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) AAA PF00004.24 ABX13579.1 - 8.1e-08 32.5 0.0 2.2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ABX13579.1 - 1.4e-06 28.4 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.6 ABX13579.1 - 2e-06 27.4 0.0 6.9e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 CDC6, C terminal AAA_17 PF13207.1 ABX13579.1 - 2e-05 25.3 0.2 6.7e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 ABX13579.1 - 4.8e-05 22.3 0.0 8.7e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 ABX13579.1 - 0.0001 22.3 0.1 0.0023 17.9 0.0 2.5 2 1 0 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 ABX13579.1 - 0.00037 20.2 4.2 0.0027 17.4 2.0 2.7 1 1 1 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 ABX13579.1 - 0.001 18.9 0.1 0.0025 17.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ABX13579.1 - 0.0021 18.3 0.1 0.0078 16.5 0.1 2.2 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.8 ABX13579.1 - 0.0023 16.8 0.0 0.014 14.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 ABX13579.1 - 0.006 16.9 3.3 0.046 14.0 2.2 2.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ABX13579.1 - 0.013 15.6 0.1 0.25 11.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.1 ABX13579.1 - 0.023 14.1 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 ABX13579.1 - 0.026 14.8 0.2 0.088 13.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 ABX13579.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 ABX13579.1 - 0.061 13.0 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 NTPase DUF87 PF01935.12 ABX13579.1 - 0.07 12.9 0.8 1 9.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 ABX13579.1 - 0.074 12.4 0.1 2.1 7.7 0.1 2.3 1 1 1 2 2 2 0 AAA-like domain NACHT PF05729.7 ABX13579.1 - 0.11 12.1 0.0 0.43 10.2 0.0 2.0 1 1 0 1 1 1 0 NACHT domain AAA_21 PF13304.1 ABX13579.1 - 0.12 12.3 7.8 0.081 12.8 3.0 2.4 2 1 0 2 2 2 0 AAA domain LON PF02190.11 ABX13581.1 - 4.4e-07 29.7 0.0 6.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain DUF1002 PF06207.6 ABX13581.1 - 0.067 12.5 0.1 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DUF1902 PF08972.6 ABX13581.1 - 0.16 11.5 0.6 0.43 10.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) OTCace_N PF02729.16 ABX13582.1 - 7.8e-41 139.0 0.0 1.2e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 ABX13582.1 - 2.5e-36 124.9 0.0 3.8e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PyrI PF01948.13 ABX13583.1 - 1.5e-35 121.0 3.0 2.6e-35 120.2 2.1 1.4 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.10 ABX13583.1 - 1.7e-14 52.9 1.9 3e-14 52.1 1.3 1.4 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF1936 PF09151.5 ABX13583.1 - 0.021 14.3 0.3 0.054 13.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) DUF2073 PF09846.4 ABX13583.1 - 0.7 9.5 3.0 0.82 9.3 0.4 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) ATP-synt_C PF00137.16 ABX13584.1 - 2.7e-20 72.0 17.0 2.7e-20 72.0 11.8 1.9 2 0 0 2 2 2 1 ATP synthase subunit C ATP-synt_D PF01813.12 ABX13585.1 - 6.8e-52 175.8 7.1 7.7e-52 175.7 4.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit D AAA_11 PF13086.1 ABX13585.1 - 0.21 11.1 1.7 0.31 10.5 1.2 1.4 1 1 0 1 1 1 0 AAA domain DUF1395 PF07160.7 ABX13585.1 - 0.35 10.3 6.6 1.4 8.3 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1395) DUF1019 PF06254.6 ABX13585.1 - 4.3 7.5 6.2 1.7 8.8 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1019) ATP-synt_ab PF00006.20 ABX13586.1 - 5e-65 218.9 0.0 7e-65 218.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 ABX13586.1 - 1.6e-12 47.9 0.1 3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 ABX13586.1 - 3.1e-11 43.3 1.1 7.8e-11 42.0 0.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 ABX13586.1 - 0.00011 22.0 2.0 0.00021 21.1 0.5 2.2 2 0 0 2 2 2 1 HAS barrel domain ATP-synt_ab PF00006.20 ABX13587.1 - 1.2e-96 322.3 0.0 1.7e-96 321.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 ABX13587.1 - 3.4e-15 56.4 0.7 5.6e-15 55.7 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 ABX13587.1 - 1e-12 48.0 0.4 2.7e-12 46.7 0.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.1 ABX13587.1 - 0.0022 17.7 0.2 0.15 11.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain Biotin_lipoyl PF00364.17 ABX13587.1 - 0.013 15.0 0.3 3.9 7.1 0.0 2.7 2 0 0 2 2 2 0 Biotin-requiring enzyme AAA_22 PF13401.1 ABX13587.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.7 ABX13587.1 - 0.071 11.4 0.4 0.16 10.3 0.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) vATP-synt_E PF01991.13 ABX13588.1 - 1.5e-24 86.3 6.6 3.8e-24 85.0 4.5 1.8 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit OSCP PF00213.13 ABX13588.1 - 0.001 18.9 6.7 0.0022 17.9 4.6 1.6 1 1 0 1 1 1 1 ATP synthase delta (OSCP) subunit Prominin PF05478.6 ABX13588.1 - 0.0089 13.6 2.1 0.011 13.2 1.5 1.1 1 0 0 1 1 1 1 Prominin DUF3584 PF12128.3 ABX13588.1 - 0.015 12.6 0.7 0.017 12.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RHD3 PF05879.7 ABX13588.1 - 0.02 12.8 2.7 0.02 12.8 1.9 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Ribosomal_L17 PF01196.14 ABX13588.1 - 0.038 14.5 1.8 0.06 13.9 0.4 1.9 1 1 1 2 2 2 0 Ribosomal protein L17 YtzH PF14165.1 ABX13588.1 - 0.048 13.8 1.5 0.75 10.0 0.1 2.9 2 1 0 3 3 3 0 YtzH-like protein DUF3236 PF11576.3 ABX13588.1 - 0.072 12.5 0.8 0.19 11.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3236) HrpE PF06188.7 ABX13588.1 - 0.12 12.1 2.6 6.8 6.3 0.4 2.2 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E GvpK PF05121.7 ABX13588.1 - 0.13 12.1 1.4 4 7.3 0.1 2.5 1 1 1 2 2 2 0 Gas vesicle protein K PhoU PF01895.14 ABX13588.1 - 0.17 12.3 5.2 0.15 12.5 1.9 2.2 2 1 1 3 3 2 0 PhoU domain Carbpep_Y_N PF05388.6 ABX13588.1 - 0.24 11.5 1.8 0.93 9.6 0.1 2.3 1 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide Cluap1 PF10234.4 ABX13588.1 - 0.27 10.4 6.3 0.2 10.8 1.9 1.9 1 1 1 2 2 2 0 Clusterin-associated protein-1 GrpE PF01025.14 ABX13588.1 - 0.31 10.5 5.1 0.47 9.9 3.5 1.3 1 0 0 1 1 1 0 GrpE Allexi_40kDa PF05549.6 ABX13588.1 - 0.34 10.1 1.7 0.48 9.6 1.0 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein Phasin PF05597.6 ABX13588.1 - 0.41 10.3 5.0 5.1 6.8 1.8 2.8 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.7 ABX13588.1 - 1.1 9.1 6.4 18 5.1 4.5 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 ABX13589.1 - 4.6e-54 183.5 9.9 1.7e-53 181.6 6.9 1.7 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family Claudin_2 PF13903.1 ABX13589.1 - 5.8 6.5 9.8 0.81 9.3 0.2 3.1 2 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF3873 PF12989.2 ABX13590.1 - 0.16 12.0 0.8 0.46 10.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3873) GAF_2 PF13185.1 ABX13591.1 - 1.9e-18 67.3 0.0 3.1e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 ABX13591.1 - 5e-12 46.0 0.0 9.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 ABX13591.1 - 3.4e-10 40.2 0.0 4.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain HTH_12 PF08461.5 ABX13591.1 - 0.0001 21.9 0.2 0.00022 20.8 0.2 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_AsnC-type PF13404.1 ABX13591.1 - 0.0043 16.5 1.0 0.034 13.6 1.2 2.2 2 1 0 2 2 2 1 AsnC-type helix-turn-helix domain Gp_dh_C PF02800.15 ABX13591.1 - 0.0053 16.2 0.0 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain HTH_WhiA PF02650.9 ABX13591.1 - 0.0068 16.7 1.0 4.2 7.8 0.2 2.6 2 0 0 2 2 2 2 WhiA C-terminal HTH domain HTH_24 PF13412.1 ABX13591.1 - 0.12 11.8 2.8 0.47 9.8 2.0 2.2 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding Nitroreductase PF00881.19 ABX13592.1 - 7e-38 130.0 0.0 8.8e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF3105 PF11303.3 ABX13592.1 - 0.17 11.7 0.3 0.31 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) Rhodanese PF00581.15 ABX13593.1 - 3.6e-42 143.2 0.0 8.1e-21 74.4 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Ammonium_transp PF00909.16 ABX13594.1 - 4e-107 358.1 35.6 1e-106 356.7 24.7 1.6 1 1 0 1 1 1 1 Ammonium Transporter Family DUF234 PF03008.9 ABX13595.1 - 0.084 13.0 0.8 0.15 12.1 0.5 1.4 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function OSCP PF00213.13 ABX13595.1 - 0.11 12.3 3.6 0.16 11.8 2.5 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit RE_R_Pab1 PF09522.5 ABX13595.1 - 0.76 9.7 4.5 0.39 10.6 0.3 2.1 2 0 0 2 2 2 0 R.Pab1 restriction endonuclease vATP-synt_AC39 PF01992.11 ABX13596.1 - 3.8e-37 128.1 5.5 4.6e-37 127.9 3.8 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Fibritin_C PF07921.7 ABX13596.1 - 0.078 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Fibritin C-terminal region Cas_Cas4 PF01930.12 ABX13597.1 - 1.2e-05 25.3 0.4 1.8e-05 24.7 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 ABX13597.1 - 0.15 11.4 2.2 0.87 8.9 0.1 2.1 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily AA_kinase PF00696.23 ABX13601.1 - 1.3e-30 106.7 1.0 1.6e-30 106.4 0.7 1.1 1 0 0 1 1 1 1 Amino acid kinase family HD PF01966.17 ABX13602.1 - 2.2e-17 63.1 0.8 4.7e-17 62.1 0.3 1.9 2 0 0 2 2 2 1 HD domain HDOD PF08668.7 ABX13602.1 - 0.043 13.0 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 HDOD domain Thymidylate_kin PF02223.12 ABX13603.1 - 1.5e-37 128.8 1.7 1.7e-37 128.6 1.2 1.0 1 0 0 1 1 1 1 Thymidylate kinase PRK PF00485.13 ABX13603.1 - 0.022 14.2 0.2 0.072 12.6 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ADK PF00406.17 ABX13603.1 - 0.047 13.5 0.7 0.18 11.6 0.5 1.9 1 1 0 1 1 1 0 Adenylate kinase 6PF2K PF01591.13 ABX13603.1 - 0.086 11.8 3.6 0.17 10.8 0.0 2.4 2 2 0 2 2 2 0 6-phosphofructo-2-kinase CO_dh PF02552.11 ABX13603.1 - 0.11 12.0 1.5 0.15 11.5 0.0 2.0 3 0 0 3 3 3 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DUF2183 PF09949.4 ABX13603.1 - 0.74 9.7 3.8 0.71 9.8 0.5 2.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2183) HSP20 PF00011.16 ABX13604.1 - 4.4e-13 48.9 0.3 5.4e-13 48.6 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ABC1 PF03109.11 ABX13605.1 - 1.9e-24 85.9 0.1 8.3e-24 83.8 0.0 2.0 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.17 ABX13605.1 - 7.7e-05 22.1 0.5 0.00016 21.0 0.4 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 ABX13605.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family NAAA-beta PF15508.1 ABX13605.1 - 0.1 12.9 1.9 20 5.5 0.0 3.6 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase PIP49_C PF12260.3 ABX13605.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 USP8_dimer PF08969.6 ABX13605.1 - 0.6 10.0 4.2 13 5.7 0.3 2.9 2 1 0 2 2 2 0 USP8 dimerisation domain AgrD PF05931.6 ABX13606.1 - 0.17 11.5 2.1 0.23 11.1 0.4 2.0 2 0 0 2 2 2 0 Staphylococcal AgrD protein KNOX2 PF03791.8 ABX13607.1 - 0.0055 15.9 0.4 0.0055 15.9 0.3 2.0 2 1 0 2 2 2 1 KNOX2 domain Tweety PF04906.8 ABX13607.1 - 0.0056 15.1 2.2 0.0068 14.8 1.5 1.0 1 0 0 1 1 1 1 Tweety Ax_dynein_light PF10211.4 ABX13607.1 - 0.0066 16.3 7.4 0.0077 16.0 5.1 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain BMFP PF04380.8 ABX13607.1 - 0.0069 16.5 3.9 0.01 15.9 2.7 1.4 1 0 0 1 1 1 1 Membrane fusogenic activity THUMP PF02926.12 ABX13607.1 - 0.0071 16.2 1.4 0.0095 15.8 1.0 1.2 1 0 0 1 1 1 1 THUMP domain DUF4097 PF13349.1 ABX13607.1 - 0.01 15.3 3.2 0.013 15.0 2.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) Baculo_p24 PF05073.7 ABX13607.1 - 0.011 15.2 4.0 0.013 15.0 2.8 1.1 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Filament PF00038.16 ABX13607.1 - 0.015 14.8 9.7 0.018 14.5 6.7 1.0 1 0 0 1 1 1 0 Intermediate filament protein Allexi_40kDa PF05549.6 ABX13607.1 - 0.02 14.1 4.1 0.023 14.0 2.9 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein IncA PF04156.9 ABX13607.1 - 0.025 14.1 18.6 0.07 12.7 12.9 1.6 1 1 0 1 1 1 0 IncA protein DUF16 PF01519.11 ABX13607.1 - 0.031 14.4 6.1 0.043 14.0 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 KxDL PF10241.4 ABX13607.1 - 0.036 13.9 3.6 0.57 10.1 1.6 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein pRN1_helical PF13010.1 ABX13607.1 - 0.037 13.6 4.1 0.049 13.2 2.8 1.1 1 0 0 1 1 1 0 Primase helical domain Spectrin PF00435.16 ABX13607.1 - 0.063 13.5 4.1 0.083 13.1 2.8 1.3 1 0 0 1 1 1 0 Spectrin repeat UPF0118 PF01594.11 ABX13607.1 - 0.064 12.2 1.0 0.073 12.0 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF20 DUF885 PF05960.6 ABX13607.1 - 0.068 12.3 2.1 0.081 12.0 1.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF342 PF03961.8 ABX13607.1 - 0.069 11.5 5.9 0.087 11.2 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ALIX_LYPXL_bnd PF13949.1 ABX13607.1 - 0.069 12.0 8.7 0.028 13.3 1.2 1.9 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Lipoprotein_7 PF01540.11 ABX13607.1 - 0.085 11.9 6.1 0.1 11.6 4.2 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Pox_polyA_pol_N PF12630.2 ABX13607.1 - 0.091 12.8 3.9 0.13 12.3 2.7 1.3 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Peptidase_M3_N PF08439.5 ABX13607.1 - 0.12 12.4 2.5 0.17 11.9 1.0 1.8 1 1 1 2 2 2 0 Oligopeptidase F V_ATPase_I PF01496.14 ABX13607.1 - 0.13 10.1 3.6 0.16 9.7 2.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 ABX13607.1 - 0.13 10.9 12.1 0.15 10.6 8.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 ABX13607.1 - 0.14 12.0 7.0 0.18 11.5 4.9 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ALMT PF11744.3 ABX13607.1 - 0.14 10.7 1.6 0.15 10.6 1.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF892 PF05974.7 ABX13607.1 - 0.15 11.8 3.3 0.23 11.2 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF892) DASH_Duo1 PF08651.5 ABX13607.1 - 0.17 11.4 8.0 0.19 11.2 1.4 2.2 1 1 1 2 2 2 0 DASH complex subunit Duo1 End3 PF12761.2 ABX13607.1 - 0.17 11.4 8.4 0.2 11.2 5.8 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 ABC2_membrane_3 PF12698.2 ABX13607.1 - 0.18 10.7 1.6 0.21 10.5 1.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein FliJ PF02050.11 ABX13607.1 - 0.19 11.7 8.9 0.26 11.3 6.2 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein Cluap1 PF10234.4 ABX13607.1 - 0.23 10.6 8.3 0.28 10.3 5.8 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF1759 PF03564.10 ABX13607.1 - 0.25 11.1 4.4 0.33 10.7 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) MerR-DNA-bind PF09278.6 ABX13607.1 - 0.31 11.4 2.3 0.67 10.3 0.5 2.3 1 1 0 2 2 1 0 MerR, DNA binding DUF1664 PF07889.7 ABX13607.1 - 0.46 10.2 4.1 0.82 9.4 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ribosomal_S13 PF00416.17 ABX13607.1 - 0.52 10.7 7.0 0.58 10.6 3.8 1.7 1 1 1 2 2 2 0 Ribosomal protein S13/S18 GLE1 PF07817.8 ABX13607.1 - 0.52 9.1 4.0 0.65 8.8 2.8 1.1 1 0 0 1 1 1 0 GLE1-like protein FUN14 PF04930.10 ABX13607.1 - 0.53 10.5 2.3 1.1 9.6 1.6 1.6 1 1 0 1 1 1 0 FUN14 family DNA_primase_lrg PF04104.9 ABX13607.1 - 0.56 9.4 3.4 0.66 9.1 2.4 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit zf-C4H2 PF10146.4 ABX13607.1 - 0.57 10.1 11.3 0.69 9.8 7.9 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4404 PF14357.1 ABX13607.1 - 0.61 10.5 7.1 0.91 9.9 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) AF0941-like PF14591.1 ABX13607.1 - 0.67 10.0 9.3 1.1 9.3 6.4 1.5 1 1 0 1 1 1 0 AF0941-like Tho2 PF11262.3 ABX13607.1 - 0.7 8.8 7.6 0.82 8.6 5.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2203 PF09969.4 ABX13607.1 - 0.74 10.0 4.4 1.2 9.4 3.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF2935 PF11155.3 ABX13607.1 - 0.94 9.5 5.7 1.9 8.5 4.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Syntaxin-6_N PF09177.6 ABX13607.1 - 1.5 9.2 7.7 2.5 8.5 5.3 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Fib_alpha PF08702.5 ABX13607.1 - 1.7 8.7 9.2 2.2 8.3 6.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ParB PF08775.5 ABX13607.1 - 1.9 8.8 8.6 3 8.1 5.9 1.3 1 1 0 1 1 1 0 ParB family Streptin-Immun PF11083.3 ABX13607.1 - 2 8.4 11.9 31 4.6 8.3 2.1 1 1 0 1 1 1 0 Lantibiotic streptin immunity protein COG2 PF06148.6 ABX13607.1 - 2.8 7.8 8.0 49 3.8 5.5 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3847 PF12958.2 ABX13607.1 - 2.8 7.7 10.8 0.83 9.4 0.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3847) Syntaxin PF00804.20 ABX13607.1 - 2.9 8.1 10.3 4.8 7.3 7.2 1.4 1 1 0 1 1 1 0 Syntaxin TMPIT PF07851.8 ABX13607.1 - 2.9 6.8 7.7 3.5 6.6 5.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.7 ABX13607.1 - 3 8.2 9.2 2.4 8.5 5.1 1.7 1 1 1 2 2 2 0 SlyX CorA PF01544.13 ABX13607.1 - 4.6 6.1 8.6 2.8 6.8 5.1 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein NPCBM_assoc PF10633.4 ABX13608.1 - 0.0003 20.7 0.5 1 9.4 0.0 3.8 3 1 1 4 4 4 2 NPCBM-associated, NEW3 domain of alpha-galactosidase EPSP_synthase PF00275.15 ABX13608.1 - 0.00067 18.1 0.0 0.001 17.5 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) ABC_tran PF00005.22 ABX13609.1 - 4.3e-33 114.5 0.2 6.6e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ABX13609.1 - 2.2e-10 40.9 0.3 7.7e-09 35.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 ABX13609.1 - 1.5e-05 24.3 5.4 0.00043 19.5 3.7 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ABX13609.1 - 1.8e-05 24.1 0.2 6e-05 22.4 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 ABX13609.1 - 0.00015 20.9 0.1 0.18 10.8 0.1 2.1 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 ABX13609.1 - 0.00027 20.1 0.2 0.0006 19.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_13 PF13166.1 ABX13609.1 - 0.00029 19.4 0.5 0.034 12.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ABX13609.1 - 0.00044 20.2 0.3 0.0023 17.9 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ABX13609.1 - 0.00046 20.3 0.5 0.0031 17.6 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 ABX13609.1 - 0.00051 19.5 0.2 0.0019 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 ABX13609.1 - 0.0027 17.1 0.1 0.046 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 ABX13609.1 - 0.0035 16.0 0.1 0.0039 15.9 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit AAA_33 PF13671.1 ABX13609.1 - 0.0038 17.1 0.7 0.007 16.2 0.5 1.7 1 1 0 1 1 1 1 AAA domain AviRa PF11599.3 ABX13609.1 - 0.0047 15.9 0.1 0.11 11.5 0.0 2.0 2 0 0 2 2 2 1 RRNA methyltransferase AviRa ABC_ATPase PF09818.4 ABX13609.1 - 0.0047 15.5 1.4 0.017 13.7 0.1 2.2 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_17 PF13207.1 ABX13609.1 - 0.006 17.4 1.0 0.0081 16.9 0.7 1.8 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ABX13609.1 - 0.0064 16.2 0.1 0.014 15.1 0.1 1.8 1 1 0 1 1 1 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 ABX13609.1 - 0.0068 15.9 0.7 0.026 14.0 0.2 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 ABX13609.1 - 0.0068 16.1 0.6 0.023 14.3 0.4 2.1 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 ABX13609.1 - 0.0077 16.1 0.1 0.018 14.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.1 ABX13609.1 - 0.009 16.3 2.8 0.015 15.6 2.0 1.6 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 ABX13609.1 - 0.013 15.1 0.1 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 ABX13609.1 - 0.014 15.2 1.8 0.035 14.0 1.2 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 ABX13609.1 - 0.017 14.7 1.0 0.05 13.2 0.2 2.1 2 1 1 3 3 3 0 NACHT domain SbcCD_C PF13558.1 ABX13609.1 - 0.019 14.8 0.0 0.26 11.2 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit KaiC PF06745.8 ABX13609.1 - 0.019 14.0 0.4 0.71 8.9 0.0 2.2 2 0 0 2 2 2 0 KaiC Dynamin_N PF00350.18 ABX13609.1 - 0.022 14.5 0.9 0.27 11.0 0.1 2.2 2 0 0 2 2 2 0 Dynamin family T2SE PF00437.15 ABX13609.1 - 0.022 13.6 0.3 0.038 12.8 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA12 PF10443.4 ABX13609.1 - 0.024 13.1 0.1 0.032 12.7 0.1 1.2 1 1 0 1 1 1 0 RNA12 protein cobW PF02492.14 ABX13609.1 - 0.025 14.0 0.7 0.087 12.2 0.0 2.1 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 ABX13609.1 - 0.034 13.2 0.0 0.066 12.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Miro PF08477.8 ABX13609.1 - 0.036 14.5 0.2 0.081 13.4 0.0 1.7 2 0 0 2 2 1 0 Miro-like protein RNA_helicase PF00910.17 ABX13609.1 - 0.073 13.2 0.0 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 ABX13609.1 - 0.12 11.1 0.8 0.28 10.0 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.1 ABX13609.1 - 0.29 11.4 1.4 0.39 11.0 1.0 1.7 1 1 0 1 1 1 0 AAA domain MacB_PCD PF12704.2 ABX13610.1 - 2e-25 89.7 1.5 4.3e-25 88.6 1.0 1.5 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.16 ABX13610.1 - 6.2e-19 67.9 6.9 6.2e-19 67.9 4.8 1.9 2 0 0 2 2 2 1 FtsX-like permease family HTH_24 PF13412.1 ABX13611.1 - 2.8e-21 74.6 4.4 4.5e-12 45.1 0.2 2.7 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 ABX13611.1 - 3.5e-20 71.2 0.6 2.8e-11 42.7 0.1 2.3 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain TrmB PF01978.14 ABX13611.1 - 2.2e-07 30.4 0.0 0.0052 16.4 0.0 2.4 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 ABX13611.1 - 2.7e-07 30.1 0.5 0.02 14.5 0.1 2.8 2 0 0 2 2 2 2 HTH domain MarR_2 PF12802.2 ABX13611.1 - 3.5e-07 29.7 0.0 0.026 14.1 0.0 2.3 2 0 0 2 2 2 2 MarR family HTH_23 PF13384.1 ABX13611.1 - 3.9e-06 26.3 0.0 0.025 14.2 0.0 2.6 2 0 0 2 2 2 2 Homeodomain-like domain MarR PF01047.17 ABX13611.1 - 2.2e-05 24.0 2.1 0.0083 15.8 0.1 3.0 3 0 0 3 3 3 1 MarR family HTH_Mga PF08280.6 ABX13611.1 - 2.3e-05 24.0 10.7 0.0018 17.9 0.7 4.4 5 0 0 5 5 4 1 M protein trans-acting positive regulator (MGA) HTH domain Mga PF05043.8 ABX13611.1 - 4.7e-05 23.5 2.6 0.0081 16.4 0.2 3.2 3 1 1 4 4 3 1 Mga helix-turn-helix domain GerE PF00196.14 ABX13611.1 - 0.00012 21.3 0.4 0.26 10.6 0.2 2.9 2 0 0 2 2 2 2 Bacterial regulatory proteins, luxR family HTH_27 PF13463.1 ABX13611.1 - 0.00053 20.2 0.0 1.2 9.5 0.0 2.4 2 0 0 2 2 2 2 Winged helix DNA-binding domain RepL PF05732.6 ABX13611.1 - 0.00054 19.1 0.0 0.17 11.0 0.0 2.4 2 0 0 2 2 2 1 Firmicute plasmid replication protein (RepL) HTH_5 PF01022.15 ABX13611.1 - 0.0011 18.5 0.2 0.7 9.6 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family Trp_repressor PF01371.14 ABX13611.1 - 0.0024 17.7 0.6 0.036 13.9 0.1 2.7 2 1 0 2 2 2 1 Trp repressor protein HTH_7 PF02796.10 ABX13611.1 - 0.0039 17.0 0.6 0.044 13.6 0.1 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 ABX13611.1 - 0.0082 16.1 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 ABX13611.1 - 0.014 15.4 0.0 0.8 9.8 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_DeoR PF08220.7 ABX13611.1 - 0.02 14.4 0.5 1.3 8.5 0.0 2.7 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain TFIIE_alpha PF02002.12 ABX13611.1 - 0.02 14.4 1.0 3.8 7.0 0.0 2.9 3 0 0 3 3 3 0 TFIIE alpha subunit HTH_40 PF14493.1 ABX13611.1 - 0.021 15.0 0.1 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2250 PF10007.4 ABX13611.1 - 0.024 14.5 1.7 3.8 7.4 0.0 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Sigma70_r4 PF04545.11 ABX13611.1 - 0.044 13.0 0.3 0.17 11.1 0.1 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 DUF1563 PF07599.6 ABX13611.1 - 0.073 12.9 1.6 0.089 12.6 0.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1563) PALP PF00291.20 ABX13611.1 - 0.085 12.0 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NUDIX PF00293.23 ABX13612.1 - 5.9e-19 68.0 0.0 7.6e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain AF0941-like PF14591.1 ABX13612.1 - 0.13 12.2 1.8 0.25 11.4 0.5 1.9 1 1 1 2 2 2 0 AF0941-like PhoU PF01895.14 ABX13613.1 - 1e-12 48.3 5.6 5.9e-09 36.2 1.5 2.7 2 0 0 2 2 2 2 PhoU domain Antitoxin-MazE PF04014.13 ABX13613.1 - 7.3e-06 25.5 0.1 1.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Antidote-toxin recognition MazE GHMP_kinases_N PF00288.21 ABX13614.1 - 2.1e-11 43.7 0.3 3.9e-11 42.8 0.2 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ABX13614.1 - 0.081 13.1 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 GHMP kinases C terminal DUF137 PF02006.11 ABX13615.1 - 5.5e-75 250.6 5.8 7e-75 250.3 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF137 TPP_enzyme_M PF00205.17 ABX13615.1 - 0.0036 17.0 1.2 0.02 14.6 0.8 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Phage_GPD PF05954.6 ABX13615.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) DUF2458 PF10454.4 ABX13615.1 - 0.09 12.6 3.6 0.21 11.4 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Orexin_rec2 PF03827.8 ABX13615.1 - 0.098 12.7 3.2 0.98 9.5 0.3 2.5 1 1 1 2 2 2 0 Orexin receptor type 2 Apo-VLDL-II PF05418.6 ABX13615.1 - 0.18 11.9 2.3 5.5 7.2 0.2 3.1 2 1 0 3 3 3 0 Apovitellenin I (Apo-VLDL-II) Lumazine_bd PF12870.2 ABX13615.1 - 0.31 11.0 3.4 0.43 10.6 0.2 2.1 2 0 0 2 2 2 0 Lumazine-binding domain Pantoate_transf PF02548.10 ABX13616.1 - 4.1e-108 360.4 4.2 4.7e-108 360.2 2.9 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 ABX13616.1 - 1.8e-05 24.1 0.6 5.3e-05 22.5 0.3 1.9 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase Peptidase_U32 PF01136.14 ABX13616.1 - 0.11 11.4 0.3 1.1 8.1 0.0 2.4 2 1 1 3 3 3 0 Peptidase family U32 GTP_EFTU_D4 PF14578.1 ABX13616.1 - 0.38 10.4 3.5 7.4 6.2 0.0 3.3 2 2 1 3 3 3 0 Elongation factor Tu domain 4 DFP PF04127.10 ABX13617.1 - 3.1e-61 206.2 5.5 4e-59 199.3 2.6 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.14 ABX13617.1 - 3.1e-26 91.5 0.2 3.1e-26 91.5 0.1 2.6 2 1 0 2 2 2 1 Flavoprotein NAD_binding_7 PF13241.1 ABX13617.1 - 0.00087 19.5 3.2 0.11 12.7 0.0 3.2 3 1 1 4 4 4 2 Putative NAD(P)-binding NAD_binding_10 PF13460.1 ABX13617.1 - 0.0011 18.9 0.0 0.0098 15.9 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding YjeF_N PF03853.10 ABX13617.1 - 0.0022 17.6 0.7 4 7.0 0.1 3.1 2 1 0 2 2 2 2 YjeF-related protein N-terminus BRCT PF00533.21 ABX13617.1 - 0.012 15.7 0.4 0.35 11.0 0.0 3.1 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Glyco_transf_4 PF13439.1 ABX13617.1 - 0.017 14.8 0.0 1.4 8.6 0.0 2.7 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Pyr_redox PF00070.22 ABX13617.1 - 0.38 11.1 2.1 49 4.4 0.0 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.1 ABX13618.1 - 7.5e-20 71.0 0.1 1.1e-19 70.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ABX13618.1 - 1.5e-17 63.8 0.0 2.6e-16 59.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 ABX13618.1 - 5e-16 58.5 0.2 3.2e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 ABX13618.1 - 3.2e-12 46.4 0.0 4.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ABX13618.1 - 9.3e-12 45.1 0.0 2.1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ABX13618.1 - 6.4e-11 42.8 0.0 1.3e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ABX13618.1 - 1.3e-09 38.4 0.0 2.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ABX13618.1 - 6.1e-07 29.1 0.0 1.6e-06 27.8 0.0 1.6 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 ABX13618.1 - 2.7e-06 26.8 0.1 5.5e-06 25.8 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 ABX13618.1 - 5.4e-06 25.9 0.0 7.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 ABX13618.1 - 3.6e-05 22.9 0.1 0.00016 20.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase CheR PF01739.13 ABX13618.1 - 0.0018 17.6 0.0 0.0045 16.2 0.0 1.6 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 ABX13618.1 - 0.0047 16.9 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ABX13618.1 - 0.0048 16.0 0.0 0.0069 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 ABX13618.1 - 0.0089 16.0 0.0 0.018 15.0 0.0 1.5 2 0 0 2 2 1 1 FtsJ-like methyltransferase PrmA PF06325.8 ABX13618.1 - 0.0092 15.1 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Gag_p30 PF02093.11 ABX13618.1 - 0.032 13.4 0.1 0.048 12.8 0.1 1.2 1 0 0 1 1 1 0 Gag P30 core shell protein Pox_MCEL PF03291.11 ABX13618.1 - 0.058 12.2 0.9 0.37 9.5 0.6 2.1 1 1 0 1 1 1 0 mRNA capping enzyme Gag_MA PF01140.14 ABX13618.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Matrix protein (MA), p15 MetW PF07021.7 ABX13618.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Glyco_tran_WecB PF03808.8 ABX13618.1 - 0.13 11.6 0.0 0.32 10.3 0.0 1.6 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Peptidase_M24 PF00557.19 ABX13620.1 - 2.2e-54 184.2 0.0 2.8e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 ABX13620.1 - 9.5e-14 52.0 0.0 1.8e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain PGBA_N PF15436.1 ABX13620.1 - 0.045 13.0 0.4 0.15 11.3 0.1 2.1 2 1 0 2 2 2 0 Plasminogen-binding protein pgbA N-terminal ThiI PF02568.9 ABX13621.1 - 8e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 ABX13621.1 - 1.7e-08 33.4 0.0 7.5e-08 31.3 0.0 1.8 2 0 0 2 2 2 1 tRNA methyl transferase DUF814 PF05670.8 ABX13621.1 - 3.8e-07 29.9 0.0 9.1e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Asn_synthase PF00733.16 ABX13621.1 - 0.0002 20.9 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 ABX13621.1 - 0.016 14.5 0.1 0.037 13.3 0.1 1.6 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF552 PF04472.7 ABX13622.1 - 1.1e-15 57.2 1.0 1.3e-15 57.0 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF552) H_kinase_N PF12282.3 ABX13622.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal transduction histidine kinase DUF4546 PF15079.1 ABX13622.1 - 0.12 11.5 0.6 0.12 11.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) Beta-Casp PF10996.3 ABX13623.1 - 1.3e-31 109.1 0.0 2.4e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 ABX13623.1 - 1e-20 74.2 0.0 2.2e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 ABX13623.1 - 2.3e-14 52.8 0.0 6.3e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 ABX13623.1 - 3.3e-12 46.3 0.0 2.7e-11 43.3 0.0 2.3 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ABX13623.1 - 0.011 15.4 0.0 0.03 14.0 0.0 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Phostensin PF13914.1 ABX13623.1 - 0.099 12.7 0.1 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region Proteasome PF00227.21 ABX13624.1 - 1.4e-52 177.7 0.3 1.6e-52 177.5 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Fe-ADH_2 PF13685.1 ABX13625.1 - 1.2e-67 227.8 0.5 1.5e-67 227.5 0.4 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 ABX13625.1 - 1.7e-25 89.4 0.2 5e-25 87.9 0.1 1.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 ABX13625.1 - 3.7e-07 29.3 0.2 5.5e-06 25.4 0.1 2.5 1 1 0 1 1 1 1 3-dehydroquinate synthase DUF640 PF04852.7 ABX13625.1 - 0.055 13.6 0.0 0.24 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF640) FKBP_C PF00254.23 ABX13626.1 - 5.8e-13 48.6 0.4 2.6e-12 46.5 0.1 2.1 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Aminotran_5 PF00266.14 ABX13627.1 - 1.1e-38 132.9 0.0 1.4e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 ABX13627.1 - 3.4e-05 22.3 0.3 5.5e-05 21.6 0.2 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 ABX13627.1 - 0.00055 19.1 0.0 0.0013 17.9 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase CTP_transf_2 PF01467.21 ABX13628.1 - 2e-17 63.6 0.0 2.5e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Citrate_ly_lig PF08218.6 ABX13628.1 - 0.047 13.1 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain UBN2_3 PF14244.1 ABX13628.1 - 0.066 12.7 0.1 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RTC PF01137.16 ABX13629.1 - 1.1e-71 240.2 0.2 1.3e-71 240.0 0.2 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase CopD PF05425.8 ABX13630.1 - 1.3e-14 54.2 1.1 1.3e-14 54.2 0.8 1.7 2 0 0 2 2 2 1 Copper resistance protein D DUF2269 PF10027.4 ABX13630.1 - 5.6e-05 22.9 7.0 7.9e-05 22.4 4.8 1.2 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) UPF0093 PF03653.8 ABX13630.1 - 0.0017 18.3 9.0 0.0039 17.1 6.2 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0093) Ytp1 PF10355.4 ABX13630.1 - 0.0035 16.5 2.2 0.0042 16.3 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF4149 PF13664.1 ABX13630.1 - 0.15 12.1 8.2 0.38 10.8 3.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Aa_trans PF01490.13 ABX13630.1 - 0.16 10.4 8.9 0.038 12.4 1.9 2.0 1 1 0 2 2 2 0 Transmembrane amino acid transporter protein DUF989 PF06181.6 ABX13630.1 - 0.17 10.9 4.3 0.053 12.6 0.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF989) DUF3278 PF11683.3 ABX13630.1 - 0.17 11.8 3.8 0.14 12.1 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) Brr6_like_C_C PF10104.4 ABX13630.1 - 2.3 7.7 8.7 0.16 11.4 1.3 2.3 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain SieB PF14163.1 ABX13630.1 - 3.1 7.3 12.9 14 5.2 0.1 2.8 2 1 0 2 2 2 0 Superinfection exclusion protein B ETRAMP PF09716.5 ABX13630.1 - 4 7.4 5.8 0.64 9.9 0.9 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF2207 PF09972.4 ABX13630.1 - 6.6 5.1 7.0 16 3.9 2.6 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) LEA_2 PF03168.8 ABX13631.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 Late embryogenesis abundant protein Nitroreductase PF00881.19 ABX13632.1 - 1.9e-28 99.3 0.0 2.6e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family CENP-B_dimeris PF09026.5 ABX13632.1 - 0.088 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FMN_red PF03358.10 ABX13633.1 - 2.5e-25 88.7 0.0 3.2e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 ABX13633.1 - 3.5e-09 36.4 0.0 4.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF1461 PF07314.6 ABX13633.1 - 0.14 11.8 0.7 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) ATG16 PF08614.6 ABX13634.1 - 0.0026 17.5 12.2 0.0031 17.3 8.4 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) PFEMP PF03011.10 ABX13634.1 - 0.0081 16.5 3.3 0.01 16.1 2.3 1.1 1 0 0 1 1 1 1 PFEMP DBL domain Reo_sigmaC PF04582.7 ABX13634.1 - 0.0095 15.1 6.8 0.012 14.8 4.7 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF3450 PF11932.3 ABX13634.1 - 0.01 15.0 2.8 0.014 14.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1664 PF07889.7 ABX13634.1 - 0.014 15.1 2.2 0.02 14.6 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 ABX13634.1 - 0.024 14.5 6.5 0.084 12.7 4.5 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Bap31 PF05529.7 ABX13634.1 - 0.047 13.1 6.7 0.073 12.5 4.5 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF443 PF04276.7 ABX13634.1 - 0.053 12.9 1.6 0.14 11.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF443) RmuC PF02646.11 ABX13634.1 - 0.076 11.8 8.8 0.06 12.1 5.4 1.4 1 1 0 1 1 1 0 RmuC family DUF641 PF04859.7 ABX13634.1 - 0.077 12.7 3.8 0.17 11.6 2.6 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Cluap1 PF10234.4 ABX13634.1 - 0.079 12.1 7.1 0.1 11.8 4.9 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 IncA PF04156.9 ABX13634.1 - 0.088 12.3 7.4 0.14 11.7 5.1 1.4 1 0 0 1 1 1 0 IncA protein MLANA PF14991.1 ABX13634.1 - 0.094 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A FA_desaturase PF00487.19 ABX13634.1 - 0.13 11.6 2.6 0.17 11.2 1.8 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Kei1 PF08552.6 ABX13634.1 - 0.14 11.7 2.5 0.19 11.3 1.7 1.3 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2244 PF10003.4 ABX13634.1 - 0.15 11.4 0.7 0.25 10.7 0.4 1.5 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) Med9 PF07544.8 ABX13634.1 - 0.15 11.8 6.0 0.38 10.5 4.1 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 CheY-binding PF09078.6 ABX13634.1 - 0.16 12.0 4.3 0.79 9.7 0.4 3.0 1 1 2 3 3 3 0 CheY binding YbbR PF07949.7 ABX13634.1 - 0.33 11.1 3.0 0.65 10.1 1.9 1.6 1 1 0 1 1 1 0 YbbR-like protein FlaC_arch PF05377.6 ABX13634.1 - 0.35 10.8 8.3 1.2 9.1 0.6 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 ABX13634.1 - 0.37 10.5 9.5 0.48 10.1 6.6 1.1 1 0 0 1 1 1 0 Laminin Domain II TBPIP PF07106.8 ABX13634.1 - 0.39 10.2 9.1 0.42 10.1 5.8 1.3 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2730 PF10805.3 ABX13634.1 - 0.47 10.2 8.7 0.41 10.4 0.9 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Fib_alpha PF08702.5 ABX13634.1 - 1.4 9.0 9.0 2.2 8.4 6.2 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 ABX13634.1 - 2.5 7.6 9.7 13 5.3 1.5 2.9 1 1 2 3 3 3 0 Septum formation initiator LRR_4 PF12799.2 ABX13634.1 - 2.6 7.7 6.2 4.4 7.0 1.3 2.8 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) V_ATPase_I PF01496.14 ABX13634.1 - 3.5 5.3 11.2 1 7.1 5.7 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family HTH_23 PF13384.1 ABX13635.1 - 0.0049 16.4 0.0 0.0086 15.6 0.0 1.6 1 1 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.5 ABX13635.1 - 0.022 14.3 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain GntR PF00392.16 ABX13635.1 - 0.076 12.4 0.1 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family TrmB PF01978.14 ABX13635.1 - 0.14 11.9 0.0 0.39 10.4 0.0 1.7 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB Pro_isomerase PF00160.16 ABX13636.1 - 3.9e-49 166.8 0.1 4.5e-49 166.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CDGSH PF09360.5 ABX13638.1 - 1.1 9.1 3.7 1.7 8.5 2.6 1.6 1 1 0 1 1 1 0 Iron-binding zinc finger CDGSH type Tap-RNA_bind PF09162.5 ABX13639.1 - 0.012 15.1 0.0 0.18 11.4 0.0 2.3 2 0 0 2 2 2 0 Tap, RNA-binding PfkB PF00294.19 ABX13641.1 - 2.9e-24 85.7 0.2 5.2e-24 84.8 0.2 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 ABX13641.1 - 1.1e-05 24.7 0.1 2.5e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 ABX13641.1 - 0.00035 19.9 0.1 0.26 10.5 0.0 2.4 2 1 0 2 2 2 2 Carbohydrate kinase NGF PF00243.13 ABX13641.1 - 0.057 13.1 0.2 0.095 12.4 0.2 1.3 1 0 0 1 1 1 0 Nerve growth factor family dUTPase_2 PF08761.6 ABX13642.1 - 2.4e-19 70.0 6.5 3.7e-14 53.1 0.2 2.0 1 1 1 2 2 2 2 dUTPase DUF550 PF04447.7 ABX13642.1 - 0.064 12.8 2.0 0.23 11.1 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF550) PRA-PH PF01503.12 ABX13642.1 - 0.065 13.5 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase MtrA PF04208.9 ABX13643.1 - 5e-30 104.2 0.1 5.6e-30 104.0 0.1 1.0 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit A FAINT PF04385.10 ABX13643.1 - 0.016 15.0 0.5 0.034 13.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function, DUF529 DegT_DnrJ_EryC1 PF01041.12 ABX13644.1 - 2e-113 379.1 0.0 2.3e-113 378.9 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 ABX13644.1 - 2.1e-09 36.8 0.0 3.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 ABX13644.1 - 3.7e-09 35.8 0.2 5.4e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 ABX13644.1 - 6.6e-07 27.9 0.5 1.3e-06 26.9 0.4 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 ABX13644.1 - 5.5e-06 25.7 0.1 1e-05 24.8 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DUF2199 PF09965.4 ABX13644.1 - 0.053 13.3 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2199) PseudoU_synth_2 PF00849.17 ABX13644.1 - 0.069 12.9 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 RNA pseudouridylate synthase Ribosomal_S5_C PF03719.10 ABX13646.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain DHQ_synthase PF01761.15 ABX13646.1 - 0.096 11.5 0.1 0.11 11.3 0.1 1.0 1 0 0 1 1 1 0 3-dehydroquinate synthase DUF479 PF04336.7 ABX13646.1 - 0.11 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF479 tRNA-synt_1b PF00579.20 ABX13647.1 - 1.7e-40 138.9 0.4 2.2e-40 138.6 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TP_methylase PF00590.15 ABX13648.1 - 5.1e-34 117.8 0.0 6.1e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NUT_C PF12882.2 ABX13648.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 NUT protein C terminal PD40 PF07676.7 ABX13649.1 - 0.29 10.8 1.5 14 5.4 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat AA_kinase PF00696.23 ABX13650.1 - 5.7e-57 193.0 0.8 5.7e-57 193.0 0.6 1.8 2 1 0 2 2 2 1 Amino acid kinase family ACT PF01842.20 ABX13650.1 - 1.6e-20 72.1 1.6 1.8e-10 40.0 0.0 2.8 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 ABX13650.1 - 3.8e-20 71.1 4.6 4.3e-12 45.3 0.2 2.7 2 0 0 2 2 2 2 ACT domain PEX11 PF05648.9 ABX13650.1 - 0.0031 16.8 0.8 0.005 16.1 0.6 1.3 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ACT_6 PF13740.1 ABX13650.1 - 0.025 14.2 1.4 0.2 11.3 0.0 3.0 3 0 0 3 3 3 0 ACT domain LytR_C PF13399.1 ABX13650.1 - 0.1 12.9 1.2 1.2 9.6 0.0 2.8 2 1 1 3 3 3 0 LytR cell envelope-related transcriptional attenuator LsmAD PF06741.8 ABX13650.1 - 0.18 11.9 1.5 0.36 10.9 1.0 1.4 1 0 0 1 1 1 0 LsmAD domain DUF4094 PF13334.1 ABX13650.1 - 0.36 11.2 4.4 0.88 10.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) PCNA_N PF00705.13 ABX13651.1 - 9.9e-20 70.3 0.1 1.8e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 ABX13651.1 - 1.2e-15 57.5 0.6 1.6e-14 53.8 0.0 2.5 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 ABX13651.1 - 0.03 13.4 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Rad9 Pox_A51 PF04948.8 ABX13651.1 - 0.04 12.5 0.2 0.053 12.1 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A51 protein Receptor_2B4 PF11465.3 ABX13651.1 - 0.11 12.4 0.1 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 TFIIS_C PF01096.13 ABX13652.1 - 4.3e-20 71.0 6.6 4.3e-20 71.0 4.6 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.2 ABX13652.1 - 6.7e-06 25.8 8.7 0.0033 17.2 1.7 2.3 2 0 0 2 2 2 2 Double zinc ribbon RNA_POL_M_15KD PF02150.11 ABX13652.1 - 0.0001 21.9 13.7 0.0089 15.6 4.0 4.0 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Elf1 PF05129.8 ABX13652.1 - 0.0006 19.4 5.5 0.11 12.2 0.1 2.3 2 0 0 2 2 2 2 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 ABX13652.1 - 0.0053 16.5 12.3 0.015 15.0 1.0 2.9 2 1 1 3 3 3 1 Transposase zinc-ribbon domain zf-DNA_Pol PF08996.5 ABX13652.1 - 0.0081 15.5 0.4 0.0081 15.5 0.2 2.3 1 1 0 2 2 2 1 DNA Polymerase alpha zinc finger Ribosomal_L44 PF00935.14 ABX13652.1 - 0.017 15.0 8.4 4.1 7.4 2.4 3.2 3 0 0 3 3 3 0 Ribosomal protein L44 zinc_ribbon_4 PF13717.1 ABX13652.1 - 0.026 14.1 17.4 0.48 10.1 0.6 4.1 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 ABX13652.1 - 0.058 12.9 17.8 0.65 9.6 0.7 4.1 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 ABX13652.1 - 0.059 12.8 16.7 0.15 11.6 3.6 3.5 3 1 0 3 3 3 0 zinc-ribbon domain Prok-RING_1 PF14446.1 ABX13652.1 - 0.087 12.5 1.6 0.087 12.5 1.1 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Ribosomal_L37e PF01907.14 ABX13652.1 - 0.097 12.4 4.5 7.9 6.3 0.1 3.2 3 0 0 3 3 3 0 Ribosomal protein L37e DUF2387 PF09526.5 ABX13652.1 - 0.11 12.4 19.3 1.2 9.0 5.6 3.7 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) zf-ribbon_3 PF13248.1 ABX13652.1 - 0.11 11.7 12.2 0.99 8.6 0.2 3.9 4 0 0 4 4 4 0 zinc-ribbon domain C1_1 PF00130.17 ABX13652.1 - 0.12 12.0 13.5 0.15 11.7 1.9 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 ABX13652.1 - 0.13 11.9 14.0 0.19 11.3 1.5 2.9 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-MYND PF01753.13 ABX13652.1 - 0.21 11.4 6.4 1.2 9.1 0.1 2.5 2 1 0 2 2 2 0 MYND finger Baculo_ME53 PF06061.6 ABX13652.1 - 0.78 8.6 11.6 0.58 9.0 2.9 2.5 1 1 0 2 2 2 0 Baculoviridae ME53 C1_4 PF07975.7 ABX13652.1 - 0.91 9.5 0.1 0.91 9.5 0.1 3.3 2 1 0 2 2 1 0 TFIIH C1-like domain zinc-ribbons_6 PF07191.7 ABX13652.1 - 1 9.1 11.8 0.081 12.7 1.0 3.0 2 1 1 3 3 3 0 zinc-ribbons Zn-ribbon_8 PF09723.5 ABX13652.1 - 1 9.3 16.3 5.7 6.9 0.0 4.2 3 1 0 4 4 4 0 Zinc ribbon domain DUF866 PF05907.8 ABX13652.1 - 1 8.7 6.5 5.2 6.5 0.2 2.3 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF866) Cytochrom_CIII PF02085.11 ABX13652.1 - 1.1 9.3 9.5 12 6.0 4.3 2.3 1 1 1 2 2 2 0 Class III cytochrome C family UPF0547 PF10571.4 ABX13652.1 - 2.6 7.8 16.3 9.1 6.0 0.2 3.9 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 Terminase_GpA PF05876.7 ABX13652.1 - 3.6 5.8 8.4 0.44 8.8 2.9 1.5 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) TF_Zn_Ribbon PF08271.7 ABX13652.1 - 4 6.8 11.4 1.1 8.6 0.2 3.4 2 2 0 2 2 2 0 TFIIB zinc-binding Lar_restr_allev PF14354.1 ABX13652.1 - 4.6 7.6 14.9 2.8 8.3 1.3 3.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF2082 PF09855.4 ABX13652.1 - 5.3 6.9 17.7 2.8 7.8 0.8 4.0 3 1 1 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-Mss51 PF13824.1 ABX13652.1 - 6.1 6.7 11.9 2.5 8.0 1.1 3.0 1 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Rubredoxin PF00301.15 ABX13652.1 - 7 6.6 14.5 22 4.9 0.4 4.1 4 0 0 4 4 4 0 Rubredoxin zf-NADH-PPase PF09297.6 ABX13652.1 - 7.7 6.1 12.3 7.9 6.0 2.7 3.6 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain DUF951 PF06107.6 ABX13652.1 - 8.8 5.9 6.2 2 8.0 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF951) DUF3795 PF12675.2 ABX13652.1 - 9.1 6.5 13.7 1.7 8.8 6.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) HypA PF01155.14 ABX13652.1 - 9.5 5.9 13.8 4.9e+02 0.4 9.5 2.6 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family RNA_pol_L_2 PF13656.1 ABX13653.1 - 4.8e-19 67.5 0.1 5.5e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF228 PF02989.9 ABX13654.1 - 0.06 12.9 0.3 0.28 10.7 0.1 1.9 2 0 0 2 2 2 0 Lyme disease proteins of unknown function Prosystemin PF07376.6 ABX13655.1 - 0.052 12.9 1.0 0.051 12.9 0.7 1.0 1 0 0 1 1 1 0 Prosystemin DSPc PF00782.15 ABX13656.1 - 1.3e-17 63.5 0.0 1.8e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ABX13656.1 - 6.4e-10 38.7 0.1 4.5e-09 35.9 0.0 1.8 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 ABX13656.1 - 2.5e-08 34.1 0.0 3.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 ABX13656.1 - 0.00086 18.7 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 ABX13656.1 - 0.0038 17.4 0.2 0.0096 16.1 0.2 1.5 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 ABX13656.1 - 0.0056 16.0 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Cyclase PF04199.8 ABX13657.1 - 1.2e-33 116.2 0.0 1.4e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase AsnC_trans_reg PF01037.16 ABX13658.1 - 2e-07 30.5 0.4 2.3e-07 30.4 0.3 1.1 1 0 0 1 1 1 1 AsnC family phage_tail_N PF08400.5 ABX13658.1 - 0.032 13.9 0.3 0.034 13.8 0.2 1.1 1 0 0 1 1 1 0 Prophage tail fibre N-terminal DUF3753 PF12575.3 ABX13658.1 - 0.11 12.2 2.2 0.31 10.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3753) Aminotran_5 PF00266.14 ABX13659.1 - 3.1e-68 230.1 0.0 3.6e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 ABX13659.1 - 3.3e-09 36.1 0.0 4.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SEO_C PF14577.1 ABX13660.1 - 0.038 13.3 0.5 0.064 12.6 0.3 1.4 1 0 0 1 1 1 0 Sieve element occlusion C-terminus HCV_NS5a_C PF12941.2 ABX13660.1 - 0.058 12.9 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region Adeno_E4_ORF3 PF06931.6 ABX13660.1 - 0.095 12.7 0.6 1 9.4 0.1 2.3 1 1 1 2 2 2 0 Mastadenovirus E4 ORF3 protein Fer4 PF00037.22 ABX13661.1 - 1.7e-11 43.2 10.5 4.3e-07 29.2 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 ABX13661.1 - 1e-09 38.6 3.7 1.5e-09 38.1 2.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 ABX13661.1 - 1.6e-09 37.2 8.6 3.7e-05 23.4 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 ABX13661.1 - 9.5e-08 31.7 3.3 1.6e-07 31.0 2.3 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 ABX13661.1 - 9.6e-08 31.7 1.6 1.4e-07 31.2 1.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 ABX13661.1 - 2.6e-07 30.1 8.9 0.0032 17.2 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 ABX13661.1 - 1.6e-05 25.0 8.2 0.00017 21.7 5.9 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 ABX13661.1 - 2.4e-05 24.3 8.2 0.032 14.5 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 ABX13661.1 - 6.3e-05 23.2 4.8 0.12 12.7 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 ABX13661.1 - 7.7e-05 22.9 12.3 0.043 14.3 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 ABX13661.1 - 0.0001 22.9 1.3 0.21 12.3 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_15 PF13459.1 ABX13661.1 - 0.00018 22.0 9.2 0.028 14.9 6.4 2.7 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_8 PF13183.1 ABX13661.1 - 0.00022 21.1 4.0 0.00063 19.7 2.9 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 ABX13661.1 - 0.00057 20.2 6.2 0.041 14.3 1.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 ABX13661.1 - 0.0026 18.0 5.6 0.056 13.7 3.8 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Guanylate_cyc PF00211.15 ABX13662.1 - 7.3e-18 64.5 0.0 1.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HAMP PF00672.20 ABX13662.1 - 2.1e-16 59.8 0.3 4.6e-16 58.7 0.2 1.6 1 0 0 1 1 1 1 HAMP domain DnaJ PF00226.26 ABX13663.1 - 3.9e-12 45.7 0.1 8.3e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Aha1_N PF09229.6 ABX13663.1 - 0.0071 16.1 1.1 0.028 14.2 0.1 2.2 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal DUF4098 PF13345.1 ABX13663.1 - 0.16 11.9 2.9 10 6.1 0.3 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4098) Usp PF00582.21 ABX13664.1 - 4.7e-31 107.8 0.0 5.6e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family AP_endonuc_2 PF01261.19 ABX13664.1 - 0.076 12.2 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel AA_permease_2 PF13520.1 ABX13665.1 - 3.1e-46 157.7 60.5 4e-46 157.4 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ABX13665.1 - 1.3e-41 142.5 55.3 1.8e-41 142.0 38.3 1.3 1 1 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 ABX13665.1 - 2.6e-09 36.1 28.0 2.6e-09 36.1 19.4 2.6 1 1 1 3 3 3 1 Spore germination protein AA_permease_C PF13906.1 ABX13665.1 - 0.082 12.7 0.5 0.082 12.7 0.3 4.5 5 1 0 5 5 5 0 C-terminus of AA_permease FlaC_arch PF05377.6 ABX13666.1 - 0.012 15.4 0.2 5.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Gln-synt_C PF00120.19 ABX13667.1 - 1.9e-84 282.8 0.0 2.3e-84 282.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 ABX13667.1 - 4.6e-23 80.5 0.1 8.4e-23 79.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Fer4_14 PF13394.1 ABX13668.1 - 1.8e-06 27.9 0.0 4.8e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 ABX13668.1 - 0.00022 21.3 0.1 0.00047 20.2 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 ABX13668.1 - 0.00023 21.3 0.0 0.00068 19.8 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily RVT_connect PF06815.8 ABX13668.1 - 0.086 12.7 0.1 0.97 9.3 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase connection domain MS_channel PF00924.13 ABX13669.1 - 5.9e-30 104.1 0.4 1.1e-29 103.2 0.2 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel Pribosyltran_N PF13793.1 ABX13670.1 - 1e-25 89.6 0.6 2.6e-24 85.1 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 ABX13670.1 - 1.7e-13 50.4 0.6 7e-13 48.3 0.1 2.3 3 0 0 3 3 3 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 ABX13670.1 - 2e-12 47.2 5.8 5.2e-12 45.8 0.6 3.1 2 2 1 3 3 3 1 Phosphoribosyl synthetase-associated domain UPRTase PF14681.1 ABX13670.1 - 0.00036 19.7 0.0 0.00062 19.0 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 ABX13670.1 - 0.00078 18.7 0.1 0.0021 17.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase GCK PF07802.6 ABX13670.1 - 0.11 12.6 0.2 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 GCK domain UPF0020 PF01170.13 ABX13671.1 - 5.2e-28 97.8 0.0 7.7e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 ABX13671.1 - 7.9e-17 61.3 0.0 1.2e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ABX13671.1 - 3.9e-14 52.5 0.8 6.2e-14 51.8 0.1 1.7 2 1 0 2 2 2 1 Methyltransferase domain N6_N4_Mtase PF01555.13 ABX13671.1 - 3.2e-11 43.1 0.0 1.5e-10 40.9 0.0 2.1 2 1 0 2 2 2 1 DNA methylase Methyltransf_25 PF13649.1 ABX13671.1 - 5e-08 33.2 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ABX13671.1 - 1.4e-07 31.0 0.0 2.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 ABX13671.1 - 3.6e-07 29.7 0.0 5.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 ABX13671.1 - 4.5e-07 30.4 0.0 7.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ABX13671.1 - 1.9e-05 23.8 0.1 3.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 ABX13671.1 - 0.00011 22.6 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ABX13671.1 - 0.00012 21.3 0.0 0.00026 20.2 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 ABX13671.1 - 0.00019 20.6 0.0 0.00036 19.6 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_5 PF01795.14 ABX13671.1 - 0.00021 20.6 0.1 0.00046 19.5 0.0 1.5 1 1 0 1 1 1 1 MraW methylase family N6_Mtase PF02384.11 ABX13671.1 - 0.00024 20.3 0.0 0.00051 19.2 0.0 1.5 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_15 PF09445.5 ABX13671.1 - 0.00044 19.8 0.2 0.024 14.1 0.0 2.4 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.10 ABX13671.1 - 0.00062 19.3 0.1 0.0015 18.0 0.0 1.8 1 1 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Met_10 PF02475.11 ABX13671.1 - 0.0018 17.9 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein THUMP PF02926.12 ABX13671.1 - 0.0034 17.2 0.4 0.0091 15.8 0.0 2.0 2 1 0 2 2 2 1 THUMP domain PCMT PF01135.14 ABX13671.1 - 0.0056 16.2 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF43 PF01861.11 ABX13671.1 - 0.0085 15.1 0.0 0.021 13.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_23 PF13489.1 ABX13671.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 ABX13671.1 - 0.039 14.4 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Lactamase_B_2 PF12706.2 ABX13672.1 - 1.8e-26 92.8 0.0 2.6e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ABX13672.1 - 3.9e-08 33.1 0.0 2e-06 27.6 0.0 2.3 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 ABX13672.1 - 0.038 13.4 0.0 0.093 12.2 0.0 1.6 2 0 0 2 2 2 0 tRNase Z endonuclease SIR2 PF02146.12 ABX13673.1 - 6.2e-54 182.4 0.0 7.9e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 ABX13673.1 - 0.0023 17.6 0.0 0.36 10.5 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain ISG65-75 PF11727.3 ABX13674.1 - 0.088 11.8 0.6 0.13 11.3 0.4 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein PP_kinase_N PF13089.1 ABX13674.1 - 0.19 11.8 1.3 0.51 10.4 0.3 2.1 1 1 1 2 2 2 0 Polyphosphate kinase N-terminal domain RNA_binding PF01877.12 ABX13675.1 - 1.8e-16 60.1 0.0 3.1e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 RNA binding AAA_18 PF13238.1 ABX13676.1 - 1.2e-14 54.7 0.1 1.6e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ABX13676.1 - 6.3e-10 39.9 0.0 9.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ABX13676.1 - 6.9e-06 26.0 0.0 1.2e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 ABX13676.1 - 0.0028 17.6 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 ABX13676.1 - 0.0042 16.8 0.3 0.31 10.7 0.1 2.2 1 1 1 2 2 2 1 NTPase AAA_22 PF13401.1 ABX13676.1 - 0.0065 16.6 0.1 0.014 15.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 ABX13676.1 - 0.0066 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 ArgK protein CoaE PF01121.15 ABX13676.1 - 0.012 15.0 0.0 0.021 14.1 0.0 1.4 1 1 0 1 1 1 0 Dephospho-CoA kinase APS_kinase PF01583.15 ABX13676.1 - 0.012 15.2 0.0 0.034 13.8 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_15 PF13175.1 ABX13676.1 - 0.023 13.7 0.0 0.024 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Cytidylate_kin2 PF13189.1 ABX13676.1 - 0.024 14.5 0.2 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA PF00004.24 ABX13676.1 - 0.03 14.5 0.2 0.073 13.2 0.2 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 ABX13676.1 - 0.031 13.8 0.1 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 ABX13676.1 - 0.043 12.9 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 ABX13676.1 - 0.048 12.5 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.5 ABX13676.1 - 0.052 12.7 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 ABX13676.1 - 0.067 13.1 0.0 0.091 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain ADK PF00406.17 ABX13676.1 - 0.071 12.9 0.1 0.1 12.4 0.1 1.3 1 1 0 1 1 1 0 Adenylate kinase AAA_14 PF13173.1 ABX13676.1 - 0.11 12.4 0.0 0.19 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 ABX13676.1 - 0.26 11.5 0.1 0.26 11.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain LigT_PEase PF02834.11 ABX13677.1 - 1.1e-25 89.4 0.0 1.6e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.4 ABX13677.1 - 1.5e-16 60.7 0.2 2e-16 60.3 0.2 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 ABX13677.1 - 1.6e-10 40.9 0.0 1.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Med1 PF10744.4 ABX13677.1 - 0.0048 15.7 0.2 0.0054 15.5 0.1 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 YPEB PF14620.1 ABX13677.1 - 0.039 12.9 0.2 0.092 11.7 0.0 1.6 2 0 0 2 2 2 0 YpeB sporulation tRNA_NucTransf2 PF09249.6 ABX13678.1 - 4.6e-40 136.0 0.2 1e-39 134.9 0.1 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain NTP_transf_2 PF01909.18 ABX13678.1 - 8.5e-09 35.6 0.6 2.3e-08 34.2 0.4 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain 7TMR-HDED PF07697.6 ABX13678.1 - 0.028 14.1 1.3 0.44 10.2 0.1 2.4 2 0 0 2 2 2 0 7TM-HD extracellular Pkinase PF00069.20 ABX13679.1 - 2.2e-06 27.0 1.3 2.2e-06 27.0 0.9 1.5 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 ABX13679.1 - 1.1e-05 24.8 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 ABX13679.1 - 0.0029 17.2 0.3 0.014 14.9 0.2 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pyr_redox_2 PF07992.9 ABX13681.1 - 1.8e-20 73.6 0.0 2.7e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ABX13681.1 - 1.8e-06 28.2 0.5 0.015 15.6 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ABX13681.1 - 0.0022 17.9 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ABX13681.1 - 0.0032 17.2 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 ABX13681.1 - 0.012 14.5 0.0 0.049 12.5 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 ABX13681.1 - 0.034 12.7 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.19 ABX13681.1 - 0.13 11.1 0.0 3.3 6.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain adh_short PF00106.20 ABX13682.1 - 1.5e-35 122.5 0.1 2.3e-35 121.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ABX13682.1 - 5.2e-19 68.9 0.8 6.7e-19 68.6 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ABX13682.1 - 7.8e-14 51.7 0.1 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ABX13682.1 - 5.3e-06 26.5 0.5 1.1e-05 25.5 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ABX13682.1 - 6.8e-05 22.4 0.3 0.015 14.7 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 ABX13682.1 - 0.0015 17.7 0.0 0.0019 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 ABX13682.1 - 0.0032 17.2 1.8 0.011 15.5 1.2 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 ABX13682.1 - 0.017 14.7 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein TYW3 PF02676.9 ABX13682.1 - 0.13 11.4 0.3 0.26 10.3 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase TYW3 zf-AN1 PF01428.11 ABX13683.1 - 3.9e-13 49.0 6.0 5.1e-13 48.6 4.2 1.1 1 0 0 1 1 1 1 AN1-like Zinc finger RecR PF02132.10 ABX13683.1 - 0.086 12.2 1.5 0.18 11.2 1.1 1.4 1 0 0 1 1 1 0 RecR protein UPF1_Zn_bind PF09416.5 ABX13683.1 - 0.092 12.3 1.3 0.1 12.1 0.9 1.2 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) Transp_Tc5_C PF04236.10 ABX13683.1 - 2.1 8.5 5.5 15 5.8 3.8 2.1 1 1 0 1 1 1 0 Tc5 transposase C-terminal domain PyrI_C PF02748.10 ABX13683.1 - 7.7 6.0 7.9 5.5 6.5 0.6 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-B_box PF00643.19 ABX13683.1 - 9.3 6.2 8.7 16 5.4 6.0 1.5 1 1 0 1 1 1 0 B-box zinc finger CLN6 PF15156.1 ABX13684.1 - 0.012 14.6 0.8 0.014 14.4 0.6 1.1 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 6 EmrE PF13536.1 ABX13684.1 - 0.021 14.9 4.8 0.027 14.6 3.3 1.2 1 0 0 1 1 1 0 Multidrug resistance efflux transporter B12D PF06522.6 ABX13684.1 - 0.1 12.3 0.4 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Kin17_mid PF10357.4 ABX13685.1 - 0.0093 15.6 1.1 2.1 7.9 0.1 2.3 2 0 0 2 2 2 2 Domain of Kin17 curved DNA-binding protein Gln-synt_C PF00120.19 ABX13686.1 - 2.8e-87 292.1 0.0 3.7e-87 291.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 ABX13686.1 - 6.7e-25 86.4 0.0 1.4e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain PepSY_TM_3 PF13706.1 ABX13687.1 - 0.086 12.2 0.9 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 PepSY-associated TM helix RseC_MucC PF04246.7 ABX13687.1 - 0.47 10.0 2.3 0.57 9.7 1.6 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC RDD PF06271.7 ABX13687.1 - 0.92 9.4 4.6 0.28 11.0 0.4 1.8 1 1 1 2 2 2 0 RDD family TMEM238 PF15125.1 ABX13687.1 - 1.3 9.0 5.2 0.5 10.3 1.9 1.6 1 1 1 2 2 2 0 TMEM238 protein family DUF308 PF03729.8 ABX13687.1 - 2.6 8.1 10.0 1.7 8.6 2.2 2.1 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Cpn60_TCP1 PF00118.19 ABX13688.1 - 1.8e-168 561.1 16.3 2e-168 560.9 11.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SHMT PF00464.14 ABX13689.1 - 6.7e-76 255.2 0.0 9.1e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 ABX13689.1 - 3.4e-08 32.8 0.1 1.2e-07 30.9 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ABX13689.1 - 1.2e-07 31.1 0.0 1.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 ABX13689.1 - 0.0002 20.2 0.1 0.00033 19.5 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class-V SelA PF03841.8 ABX13689.1 - 0.0018 17.0 0.0 0.0032 16.2 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Pyridoxal_deC PF00282.14 ABX13689.1 - 0.01 14.3 0.0 0.017 13.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain PolC_DP2 PF03833.8 ABX13690.1 - 7.7e-269 894.1 0.1 3.2e-268 892.0 0.1 1.8 1 1 0 1 1 1 1 DNA polymerase II large subunit DP2 PcrB PF01884.12 ABX13691.1 - 2.4e-67 226.5 0.2 2.9e-67 226.3 0.1 1.0 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.16 ABX13691.1 - 1.3e-07 31.1 0.2 1.1e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein IMPDH PF00478.20 ABX13691.1 - 5.2e-06 25.5 0.8 2.3e-05 23.4 0.6 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.15 ABX13691.1 - 0.00061 18.3 1.8 0.005 15.4 0.1 2.5 2 1 1 3 3 3 1 Tryptophan synthase alpha chain IGPS PF00218.16 ABX13691.1 - 0.0061 15.6 0.2 0.16 10.9 0.0 2.5 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase Ribul_P_3_epim PF00834.14 ABX13691.1 - 0.0078 15.3 0.3 0.027 13.5 0.1 1.8 2 0 0 2 2 2 1 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.12 ABX13691.1 - 0.0079 15.3 0.0 0.094 11.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI DHO_dh PF01180.16 ABX13691.1 - 0.012 14.5 1.3 0.02 13.8 0.1 1.7 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NanE PF04131.9 ABX13691.1 - 0.019 13.9 1.9 0.74 8.7 0.0 2.5 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 ABX13691.1 - 0.028 13.4 1.0 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DeoC PF01791.4 ABX13691.1 - 0.037 13.3 0.5 0.17 11.1 0.1 1.9 2 0 0 2 2 2 0 DeoC/LacD family aldolase Dus PF01207.12 ABX13691.1 - 0.041 12.6 0.0 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) NMO PF03060.10 ABX13691.1 - 0.06 12.4 0.8 1.4 8.0 0.1 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase FMN_dh PF01070.13 ABX13691.1 - 0.11 11.3 0.0 0.27 10.0 0.0 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase YwpF PF14183.1 ABX13692.1 - 0.1 12.2 0.2 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 YwpF-like protein HTH_27 PF13463.1 ABX13693.1 - 1.5e-06 28.4 0.1 2.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.14 ABX13693.1 - 2.1e-05 24.1 0.9 4.2e-05 23.1 0.1 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Replic_Relax PF13814.1 ABX13693.1 - 0.008 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Replication-relaxation Ribosomal_L27e PF01777.13 ABX13693.1 - 0.013 15.5 0.7 0.013 15.5 0.5 2.2 3 0 0 3 3 3 0 Ribosomal L27e protein family HTH_45 PF14947.1 ABX13693.1 - 0.024 14.4 1.3 0.058 13.2 0.2 2.2 2 1 0 2 2 2 0 Winged helix-turn-helix MarR PF01047.17 ABX13693.1 - 0.027 14.1 0.3 0.072 12.8 0.2 1.7 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.1 ABX13693.1 - 0.055 12.8 0.1 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PBS_linker_poly PF00427.16 ABX13693.1 - 0.059 13.0 0.9 0.12 11.9 0.2 1.8 2 0 0 2 2 2 0 Phycobilisome Linker polypeptide HTH_34 PF13601.1 ABX13693.1 - 0.07 13.1 0.2 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR_2 PF12802.2 ABX13693.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 ABX13693.1 - 0.087 12.9 1.3 0.61 10.2 0.1 2.4 2 1 0 2 2 2 0 Transcriptional regulator DUF2250 PF10007.4 ABX13693.1 - 0.14 12.0 1.5 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Antitoxin-MazE PF04014.13 ABX13694.1 - 1.8e-07 30.7 0.2 2.1e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 Antidote-toxin recognition MazE MraZ PF02381.13 ABX13694.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 MraZ protein Penicillinase_R PF03965.11 ABX13695.1 - 0.00084 19.4 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Penicillinase repressor HHH_2 PF12826.2 ABX13695.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif