# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Cdc6_C PF09079.11 ABX11901.1 - 2.5e-16 59.4 1.3 6.5e-16 58.1 0.5 2.1 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 ABX11901.1 - 9.7e-14 51.8 0.2 3e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ABX11901.1 - 8.6e-12 45.6 1.0 3.8e-11 43.5 0.4 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ABX11901.1 - 2.1e-10 41.2 0.3 2.6e-09 37.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 ABX11901.1 - 3.1e-07 30.0 0.1 5.2e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 ABX11901.1 - 5e-07 29.8 0.0 8.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 ABX11901.1 - 9e-07 29.0 6.5 1.2e-06 28.7 3.6 2.4 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 ABX11901.1 - 9.6e-06 25.0 0.3 0.13 11.5 0.1 2.5 2 0 0 2 2 2 2 KAP family P-loop domain PIF1 PF05970.14 ABX11901.1 - 7.1e-05 22.1 0.1 0.00032 20.0 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.9 ABX11901.1 - 0.00012 21.4 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 ABX11901.1 - 0.00026 20.3 0.1 0.0007 18.9 0.1 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 ABX11901.1 - 0.00032 21.0 0.3 0.0016 18.8 0.1 2.3 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 ABX11901.1 - 0.00093 19.1 0.6 0.12 12.3 0.1 2.4 2 0 0 2 2 2 1 NTPase DUF815 PF05673.13 ABX11901.1 - 0.0012 18.0 0.0 0.003 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 ABX11901.1 - 0.0016 18.0 0.1 0.0053 16.3 0.1 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 ABX11901.1 - 0.0017 18.4 0.2 0.0052 16.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ABX11901.1 - 0.0019 18.6 0.1 0.0073 16.7 0.0 2.0 2 0 0 2 2 1 1 RNA helicase ATPase PF06745.13 ABX11901.1 - 0.0041 16.5 0.1 0.35 10.2 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_11 PF13086.6 ABX11901.1 - 0.0043 16.9 3.5 0.033 14.0 3.3 2.2 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ABX11901.1 - 0.014 14.8 0.0 0.034 13.5 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 ABX11901.1 - 0.015 15.6 0.3 0.048 14.0 0.3 1.9 1 0 0 1 1 1 0 AAA C-terminal domain AAA_32 PF13654.6 ABX11901.1 - 0.017 13.9 2.3 0.44 9.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 ABX11901.1 - 0.019 13.9 0.0 0.094 11.6 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 ABX11901.1 - 0.024 14.6 3.5 0.074 13.0 0.1 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 ABX11901.1 - 0.03 14.0 1.4 0.16 11.7 1.4 2.1 1 1 0 1 1 1 0 AAA domain HTH_36 PF13730.6 ABX11901.1 - 0.042 13.8 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 1 0 Helix-turn-helix domain AAA_30 PF13604.6 ABX11901.1 - 0.048 13.4 0.2 0.33 10.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 ABX11901.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF512 PF04459.12 ABX11901.1 - 0.052 12.8 0.6 0.29 10.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF512) TIP49_C PF17856.1 ABX11901.1 - 0.07 13.3 0.1 0.22 11.7 0.1 1.9 1 0 0 1 1 1 0 TIP49 AAA-lid domain Sigma54_activat PF00158.26 ABX11901.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 ABX11901.1 - 0.097 12.4 1.0 3.4 7.4 0.0 3.0 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Methyltr_RsmB-F PF01189.17 ABX11901.1 - 0.097 12.3 0.1 1.8 8.1 0.0 2.7 3 0 0 3 3 3 0 16S rRNA methyltransferase RsmB/F AAA_33 PF13671.6 ABX11901.1 - 0.12 12.6 0.2 0.64 10.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain Tfb5 PF06331.12 ABX11901.1 - 1 9.4 5.1 28 4.8 0.2 3.3 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 DNA_pol_E_B PF04042.16 ABX11902.1 - 9.5e-25 87.2 0.0 1.8e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos PF00149.28 ABX11902.1 - 5.3e-12 46.7 0.0 9.6e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ABX11902.1 - 4.5e-08 33.5 0.0 1.1e-07 32.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain tRNA_anti-codon PF01336.25 ABX11902.1 - 0.00027 20.9 0.1 0.00059 19.8 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1080 PF06439.11 ABX11902.1 - 0.16 12.0 0.1 0.26 11.4 0.1 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) SpoIIM PF01944.17 ABX11903.1 - 9.4e-08 32.2 9.1 1e-07 32.1 9.1 1.1 1 0 0 1 1 1 1 Stage II sporulation protein M Copper-bind PF00127.20 ABX11904.1 - 0.00076 19.9 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family TP_methylase PF00590.20 ABX11905.1 - 1.1e-36 126.7 0.0 1.3e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases bPH_3 PF14470.6 ABX11906.1 - 0.0026 18.1 0.5 0.75 10.2 0.0 2.4 2 1 0 2 2 2 2 Bacterial PH domain Vps36_ESCRT-II PF11605.8 ABX11906.1 - 0.041 14.1 0.1 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 HEPN_RES_NTD1 PF18870.1 ABX11906.1 - 0.056 13.6 5.5 12 6.1 5.5 2.3 1 1 0 1 1 1 0 HEPN/RES N-terminal domain 1 Pro_isomerase PF00160.21 ABX11907.1 - 1.2e-47 162.1 0.1 1.8e-47 161.6 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lpp-LpqN PF10738.9 ABX11907.1 - 0.029 13.8 0.1 0.048 13.1 0.1 1.3 1 0 0 1 1 1 0 Probable lipoprotein LpqN PsbP PF01789.16 ABX11907.1 - 0.048 13.8 0.5 0.19 11.9 0.5 2.0 1 1 0 1 1 1 0 PsbP Pyr_redox_2 PF07992.14 ABX11908.1 - 2.3e-51 174.8 0.0 2.8e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABX11908.1 - 3.2e-16 59.7 0.2 5.9e-11 42.8 0.1 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABX11908.1 - 5.7e-06 26.2 0.0 2.7 7.5 0.0 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ABX11908.1 - 0.0012 18.1 0.0 0.0063 15.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABX11908.1 - 0.02 14.0 0.0 3 6.8 0.0 2.6 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ABX11908.1 - 0.043 12.9 0.0 34 3.4 0.0 3.2 3 0 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.6 ABX11908.1 - 0.12 12.7 0.0 15 5.9 0.0 2.6 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ABX11908.1 - 0.15 12.1 0.0 29 4.6 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding ACT_7 PF13840.6 ABX11909.1 - 1.4e-06 28.0 0.1 2.3e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 ACT domain SecD-TM1 PF13721.6 ABX11909.1 - 0.017 15.6 0.1 0.042 14.3 0.1 1.6 1 0 0 1 1 1 0 SecD export protein N-terminal TM region HSP20 PF00011.21 ABX11910.1 - 4.9e-05 23.4 4.5 0.0012 18.9 4.5 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family PIH1_CS PF18201.1 ABX11910.1 - 0.0002 21.7 0.2 0.00027 21.3 0.2 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 ABX11910.1 - 0.0099 15.4 0.1 0.021 14.4 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA AAA PF00004.29 ABX11911.1 - 1.6e-100 332.7 0.0 3e-51 173.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ABX11911.1 - 2.3e-24 84.9 5.6 3.1e-12 46.1 0.5 2.9 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 ABX11911.1 - 1.1e-23 83.1 0.0 3.1e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 ABX11911.1 - 6.6e-16 58.9 0.3 3.2e-07 30.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ABX11911.1 - 6.2e-15 55.3 0.0 6.9e-08 32.4 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ABX11911.1 - 2.3e-14 54.1 0.0 8e-06 26.3 0.0 3.6 2 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 ABX11911.1 - 8.7e-13 48.5 1.2 8.6e-05 22.5 0.2 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 ABX11911.1 - 2.3e-11 43.3 0.1 4.9e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 ABX11911.1 - 2.5e-10 40.7 0.0 0.00014 22.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ABX11911.1 - 2.8e-10 40.6 2.0 0.0049 17.1 0.1 4.2 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 ABX11911.1 - 4.4e-10 39.3 0.0 0.00055 19.2 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 ABX11911.1 - 2.5e-09 37.2 0.0 0.00031 20.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ABX11911.1 - 5.2e-08 33.5 0.0 0.0024 18.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 ABX11911.1 - 9.6e-08 32.0 0.0 0.016 14.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 ABX11911.1 - 1.8e-07 30.8 0.7 0.016 14.6 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ABX11911.1 - 3.6e-07 30.1 0.1 0.0049 16.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 ABX11911.1 - 4.5e-07 29.7 0.2 0.12 12.0 0.0 4.1 2 2 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 ABX11911.1 - 6.6e-07 29.7 0.0 0.066 13.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 ABX11911.1 - 8.8e-07 28.4 0.1 0.0084 15.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_7 PF12775.7 ABX11911.1 - 2.7e-06 27.0 0.2 0.1 12.1 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 ABX11911.1 - 4.1e-06 27.1 0.1 0.12 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 ABX11911.1 - 7.2e-06 26.6 0.1 0.23 12.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_3 PF07726.11 ABX11911.1 - 8.4e-06 25.7 0.0 0.032 14.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ABX11911.1 - 9.3e-06 25.3 0.3 1 8.9 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_11 PF13086.6 ABX11911.1 - 2.6e-05 24.1 0.0 0.077 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 ABX11911.1 - 3.8e-05 23.7 0.1 0.34 10.9 0.1 2.7 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 ABX11911.1 - 5.9e-05 22.9 0.3 0.13 12.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 ABX11911.1 - 7.3e-05 22.0 0.0 0.24 10.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 ABX11911.1 - 0.0001 21.5 0.2 0.19 10.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 ABX11911.1 - 0.00015 21.3 0.2 0.5 9.8 0.1 2.6 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 ABX11911.1 - 0.00042 19.7 0.0 0.95 8.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 ABX11911.1 - 0.00042 20.3 0.5 2.5 8.0 0.1 3.7 4 0 0 4 4 3 1 NACHT domain Sigma54_activ_2 PF14532.6 ABX11911.1 - 0.00049 20.2 0.0 0.88 9.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase PF06745.13 ABX11911.1 - 0.00072 19.0 4.2 0.4 10.0 0.1 3.8 3 1 1 4 4 3 1 KaiC AAA_17 PF13207.6 ABX11911.1 - 0.0017 18.8 0.0 1.9 8.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain Guanylate_kin PF00625.21 ABX11911.1 - 0.0029 17.3 0.9 11 5.6 0.1 4.2 3 1 1 4 4 4 0 Guanylate kinase TniB PF05621.11 ABX11911.1 - 0.003 17.0 0.0 1.7 8.0 0.0 3.3 3 0 0 3 3 3 1 Bacterial TniB protein AAA_19 PF13245.6 ABX11911.1 - 0.0033 17.8 3.2 1.5 9.1 0.0 3.4 4 0 0 4 4 2 1 AAA domain ResIII PF04851.15 ABX11911.1 - 0.0045 17.0 0.0 0.81 9.7 0.0 2.9 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit CPT PF07931.12 ABX11911.1 - 0.0054 16.6 0.1 0.28 11.0 0.0 2.7 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Bac_DnaA PF00308.18 ABX11911.1 - 0.0068 16.3 0.0 0.96 9.2 0.0 2.8 2 1 0 2 2 2 1 Bacterial dnaA protein NB-ARC PF00931.22 ABX11911.1 - 0.0075 15.5 0.1 4 6.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Cytidylate_kin PF02224.18 ABX11911.1 - 0.0077 16.0 1.6 5 6.8 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase Rad17 PF03215.15 ABX11911.1 - 0.012 15.6 0.0 1.2 9.0 0.0 2.7 2 1 0 2 2 2 0 Rad17 P-loop domain Hydin_ADK PF17213.3 ABX11911.1 - 0.014 15.7 0.5 0.16 12.2 0.0 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain ATPase_2 PF01637.18 ABX11911.1 - 0.014 15.3 0.6 0.85 9.5 0.1 3.4 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 ABX11911.1 - 0.019 14.0 0.0 4.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein SKI PF01202.22 ABX11911.1 - 0.023 14.8 0.1 6.1 6.9 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.15 ABX11911.1 - 0.025 14.5 6.7 3.1 7.7 0.0 4.5 4 1 1 5 5 4 0 NTPase AFG1_ATPase PF03969.16 ABX11911.1 - 0.03 13.2 0.0 6.5 5.5 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase PIF1 PF05970.14 ABX11911.1 - 0.031 13.4 0.1 4.6 6.3 0.0 2.9 2 1 1 3 3 3 0 PIF1-like helicase Viral_helicase1 PF01443.18 ABX11911.1 - 0.033 13.9 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IPT PF01745.16 ABX11911.1 - 0.039 13.3 0.3 5.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase Vps4_C PF09336.10 ABX11911.1 - 0.04 13.9 0.3 0.21 11.6 0.1 2.3 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain Torsin PF06309.11 ABX11911.1 - 0.052 13.7 0.1 2.4 8.3 0.0 2.7 2 0 0 2 2 2 0 Torsin KTI12 PF08433.10 ABX11911.1 - 0.16 11.4 0.4 9.2 5.6 0.0 2.9 3 0 0 3 3 2 0 Chromatin associated protein KTI12 Leu_zip PF15294.6 ABX11912.1 - 4.4e-06 26.4 2.3 5.5e-06 26.1 2.3 1.1 1 0 0 1 1 1 1 Leucine zipper UPF0242 PF06785.11 ABX11912.1 - 6e-06 26.5 1.2 7.2e-06 26.2 1.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 ABX11912.1 - 2.2e-05 25.0 3.7 2.4e-05 24.9 3.7 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region TonB_N PF16031.5 ABX11912.1 - 3.2e-05 24.5 10.5 3.9e-05 24.2 10.5 1.1 1 0 0 1 1 1 1 TonB polyproline region HOOK PF05622.12 ABX11912.1 - 6e-05 21.4 5.1 7.1e-05 21.2 5.1 1.0 1 0 0 1 1 1 1 HOOK protein CENP-F_leu_zip PF10473.9 ABX11912.1 - 7.1e-05 22.9 10.5 9.6e-05 22.4 10.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4763 PF15960.5 ABX11912.1 - 0.00012 21.5 0.5 0.00014 21.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) ADIP PF11559.8 ABX11912.1 - 0.00013 22.0 8.7 0.00018 21.6 8.7 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 ABX11912.1 - 0.00014 22.1 0.8 0.00017 21.9 0.8 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ZapB PF06005.12 ABX11912.1 - 0.00014 22.2 13.1 0.00038 20.8 13.1 1.7 1 1 0 1 1 1 1 Cell division protein ZapB Cast PF10174.9 ABX11912.1 - 0.00018 20.0 2.9 0.00021 19.7 2.9 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Phage_GP20 PF06810.11 ABX11912.1 - 0.00019 21.2 4.4 0.00026 20.8 4.4 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF5082 PF16888.5 ABX11912.1 - 0.00027 21.2 6.3 0.00038 20.7 6.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) Spc7 PF08317.11 ABX11912.1 - 0.00044 19.2 8.3 0.00054 18.9 8.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4795 PF16043.5 ABX11912.1 - 0.00066 19.3 0.1 0.00066 19.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) KASH_CCD PF14662.6 ABX11912.1 - 0.00066 19.6 10.3 0.00084 19.2 10.3 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF720 PF05302.11 ABX11912.1 - 0.00075 19.3 0.8 0.0011 18.8 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF720) Jnk-SapK_ap_N PF09744.9 ABX11912.1 - 0.00084 19.6 6.2 0.0013 19.0 6.2 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 HALZ PF02183.18 ABX11912.1 - 0.0012 19.1 6.3 0.021 15.0 3.2 2.3 1 1 1 2 2 2 2 Homeobox associated leucine zipper CtIP_N PF10482.9 ABX11912.1 - 0.0021 18.1 7.2 0.0037 17.3 7.2 1.4 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain AAA_13 PF13166.6 ABX11912.1 - 0.0028 16.4 5.7 0.0035 16.0 5.7 1.0 1 0 0 1 1 1 1 AAA domain Wtap PF17098.5 ABX11912.1 - 0.0029 17.6 6.5 0.0037 17.2 6.5 1.1 1 0 0 1 1 1 1 WTAP/Mum2p family Dynamitin PF04912.14 ABX11912.1 - 0.003 17.0 3.4 0.0037 16.7 3.4 1.1 1 0 0 1 1 1 1 Dynamitin BRE1 PF08647.11 ABX11912.1 - 0.0033 17.5 9.2 0.0047 17.0 9.2 1.1 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase FmiP_Thoc5 PF09766.9 ABX11912.1 - 0.0042 16.4 1.6 0.0079 15.5 1.8 1.4 2 0 0 2 2 1 1 Fms-interacting protein/Thoc5 DUF3450 PF11932.8 ABX11912.1 - 0.0062 15.9 9.1 0.0087 15.4 9.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DivIC PF04977.15 ABX11912.1 - 0.0065 16.2 12.9 0.0093 15.7 5.6 2.2 1 1 1 2 2 2 2 Septum formation initiator bZIP_1 PF00170.21 ABX11912.1 - 0.0068 16.5 9.2 0.025 14.7 5.0 2.2 1 1 2 3 3 3 2 bZIP transcription factor DUF3584 PF12128.8 ABX11912.1 - 0.0074 13.9 3.9 0.0089 13.6 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4407 PF14362.6 ABX11912.1 - 0.01 15.2 3.8 0.014 14.7 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SHE3 PF17078.5 ABX11912.1 - 0.013 15.3 8.2 0.038 13.7 8.2 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 JIP_LZII PF16471.5 ABX11912.1 - 0.022 14.9 6.7 2.9 8.1 6.7 2.3 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Csm1_N PF18504.1 ABX11912.1 - 0.025 14.9 8.6 0.045 14.1 8.6 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain LRRFIP PF09738.9 ABX11912.1 - 0.027 13.9 8.9 0.13 11.8 8.8 1.8 1 1 0 1 1 1 0 LRRFIP family TPR_MLP1_2 PF07926.12 ABX11912.1 - 0.033 14.3 9.0 0.066 13.3 9.0 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 ABX11912.1 - 0.037 14.4 2.5 0.037 14.4 2.5 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) KELK PF15796.5 ABX11912.1 - 0.041 14.3 1.0 0.041 14.3 1.0 2.2 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HMMR_C PF15908.5 ABX11912.1 - 0.046 14.0 3.9 0.068 13.4 3.9 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Cep57_CLD_2 PF14197.6 ABX11912.1 - 0.052 13.6 7.5 0.078 13.1 7.2 1.4 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF1465 PF07323.12 ABX11912.1 - 0.057 13.3 2.5 0.076 12.9 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) BLOC1_2 PF10046.9 ABX11912.1 - 0.06 13.6 6.8 0.092 13.1 6.8 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CALCOCO1 PF07888.11 ABX11912.1 - 0.065 12.1 6.5 0.08 11.8 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like XhlA PF10779.9 ABX11912.1 - 0.074 13.3 8.1 0.16 12.2 7.0 2.0 1 1 0 1 1 1 0 Haemolysin XhlA DUF4988 PF16378.5 ABX11912.1 - 0.076 12.7 2.8 0.063 12.9 1.4 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF2968 PF11180.8 ABX11912.1 - 0.078 12.6 7.0 0.1 12.2 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) SKA2 PF16740.5 ABX11912.1 - 0.085 12.6 5.2 0.15 11.8 5.2 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 FliD_C PF07195.12 ABX11912.1 - 0.097 12.1 5.1 0.12 11.8 5.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus TMF_DNA_bd PF12329.8 ABX11912.1 - 0.1 12.6 14.3 0.17 11.9 14.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 ABX11912.1 - 0.12 12.4 4.5 0.16 12.0 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Trypan_PARP PF05887.11 ABX11912.1 - 0.12 12.3 23.1 0.2 11.7 23.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Tropomyosin_1 PF12718.7 ABX11912.1 - 0.14 12.3 8.9 0.22 11.7 8.9 1.2 1 0 0 1 1 1 0 Tropomyosin like DivIVA PF05103.13 ABX11912.1 - 0.15 12.1 6.4 0.54 10.3 6.4 1.7 1 1 0 1 1 1 0 DivIVA protein PikAIV_N PF18605.1 ABX11912.1 - 0.18 11.4 2.9 0.4 10.3 2.9 1.7 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain TMPIT PF07851.13 ABX11912.1 - 0.19 11.0 5.8 0.26 10.5 5.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Prominin PF05478.11 ABX11912.1 - 0.19 9.6 5.0 0.25 9.3 5.0 1.1 1 0 0 1 1 1 0 Prominin bZIP_2 PF07716.15 ABX11912.1 - 0.2 11.8 14.0 0.28 11.3 6.1 2.5 1 1 0 2 2 2 0 Basic region leucine zipper RNA_pol_Rpb1_1 PF04997.12 ABX11912.1 - 0.21 10.9 5.1 0.27 10.6 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 GLE1 PF07817.13 ABX11912.1 - 0.23 10.7 3.4 0.34 10.1 3.4 1.3 1 0 0 1 1 1 0 GLE1-like protein 5_nucleotid PF05761.14 ABX11912.1 - 0.23 10.3 1.9 0.36 9.7 1.9 1.2 1 0 0 1 1 1 0 5' nucleotidase family Seryl_tRNA_N PF02403.22 ABX11912.1 - 0.24 11.6 8.5 0.32 11.2 8.5 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fungal_TACC PF12709.7 ABX11912.1 - 0.24 11.9 10.4 0.11 13.0 6.5 2.0 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4164 PF13747.6 ABX11912.1 - 0.25 11.7 4.3 0.36 11.1 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DASH_Hsk3 PF08227.11 ABX11912.1 - 0.25 11.7 7.4 0.41 11.0 0.2 2.4 1 1 1 2 2 2 0 DASH complex subunit Hsk3 like GrpE PF01025.19 ABX11912.1 - 0.26 11.0 5.1 0.36 10.5 5.1 1.3 1 0 0 1 1 1 0 GrpE HemX PF04375.14 ABX11912.1 - 0.27 10.5 7.7 0.35 10.1 7.7 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2205 PF10224.9 ABX11912.1 - 0.3 11.1 6.4 0.36 10.8 1.4 2.2 1 1 1 2 2 2 0 Short coiled-coil protein Rho_Binding PF08912.11 ABX11912.1 - 0.33 11.8 10.1 0.52 11.2 1.2 2.3 1 1 1 2 2 2 0 Rho Binding Atg14 PF10186.9 ABX11912.1 - 0.37 9.8 7.7 0.49 9.4 7.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 ABX11912.1 - 0.37 10.6 5.7 0.5 10.2 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 ABX11912.1 - 0.45 11.2 7.7 0.95 10.1 7.7 1.6 1 1 0 1 1 1 0 Initiation control protein YabA TolA_bind_tri PF16331.5 ABX11912.1 - 0.5 10.5 13.5 15 5.7 13.7 2.1 1 1 0 1 1 1 0 TolA binding protein trimerisation TSC22 PF01166.18 ABX11912.1 - 0.5 10.7 11.4 0.72 10.2 2.4 2.8 1 1 2 3 3 3 0 TSC-22/dip/bun family GIT_CC PF16559.5 ABX11912.1 - 0.65 9.9 9.6 0.43 10.5 7.6 1.7 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2312 PF10073.9 ABX11912.1 - 0.67 9.6 5.4 9 6.0 0.5 2.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) LPP PF04728.13 ABX11912.1 - 0.94 9.9 5.8 2.4 8.6 1.3 2.2 1 1 2 3 3 3 0 Lipoprotein leucine-zipper Swi5 PF07061.11 ABX11912.1 - 0.95 9.6 8.3 17 5.6 8.7 2.1 1 1 1 2 2 2 0 Swi5 Snapin_Pallidin PF14712.6 ABX11912.1 - 1.1 9.7 9.9 1.1 9.7 7.1 1.9 1 1 1 2 2 2 0 Snapin/Pallidin Sas6_CC PF18594.1 ABX11912.1 - 1.2 9.0 4.3 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Spc24 PF08286.11 ABX11912.1 - 1.5 9.1 8.3 4.1 7.7 8.3 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4140 PF13600.6 ABX11912.1 - 1.6 9.2 5.3 4.7 7.7 5.0 1.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3552 PF12072.8 ABX11912.1 - 1.7 8.1 10.7 2.2 7.7 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PRKG1_interact PF15898.5 ABX11912.1 - 1.9 9.4 10.1 4.7 8.2 3.6 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF5320 PF17253.2 ABX11912.1 - 2.2 9.4 7.3 8.5 7.5 2.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Cnn_1N PF07989.11 ABX11912.1 - 2.8 8.2 16.0 0.24 11.6 2.0 2.5 2 1 1 3 3 2 0 Centrosomin N-terminal motif 1 TFIIB PF00382.19 ABX11913.1 - 5.9e-29 99.9 2.2 5.8e-14 51.9 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ABX11913.1 - 1.4e-05 24.5 0.4 2.9e-05 23.5 0.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 ABX11913.1 - 0.0019 18.0 0.1 0.08 12.7 0.1 2.2 1 1 1 2 2 2 1 Cyclin, N-terminal domain HTH_19 PF12844.7 ABX11913.1 - 0.11 12.6 1.4 16 5.6 0.0 3.1 3 1 0 3 3 3 0 Helix-turn-helix domain DUF1059 PF06348.11 ABX11914.1 - 0.012 15.9 0.3 0.022 15.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) AAA_lid_9 PF17871.1 ABX11914.1 - 0.032 14.1 0.1 0.045 13.7 0.1 1.1 1 0 0 1 1 1 0 AAA lid domain CRCB PF02537.15 ABX11915.1 - 2.3e-19 69.5 5.2 2.8e-19 69.2 5.2 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) DUF2104 PF09877.9 ABX11915.1 - 0.0082 16.4 1.5 0.0099 16.1 0.5 1.7 1 1 0 1 1 1 1 Predicted membrane protein (DUF2104) CARDB PF07705.11 ABX11919.1 - 0.009 16.3 0.3 0.025 14.9 0.1 1.8 2 0 0 2 2 2 1 CARDB TFIIB PF00382.19 ABX11920.1 - 8.4e-33 112.3 6.7 8.4e-16 57.8 0.4 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ABX11920.1 - 2.5e-09 36.5 0.4 4.5e-09 35.7 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_11 PF08279.12 ABX11920.1 - 0.0025 17.7 0.3 0.15 12.0 0.0 3.0 3 0 0 3 3 3 1 HTH domain Cyclin_N PF00134.23 ABX11920.1 - 0.01 15.6 0.3 0.087 12.6 0.1 2.1 2 0 0 2 2 2 0 Cyclin, N-terminal domain Sigma70_r4 PF04545.16 ABX11920.1 - 0.011 15.3 0.0 0.031 13.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 zinc_ribbon_2 PF13240.6 ABX11920.1 - 0.012 15.3 1.3 0.062 13.0 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain RPA_interact_C PF14768.6 ABX11920.1 - 0.012 16.1 0.0 0.037 14.6 0.0 1.9 1 0 0 1 1 1 0 Replication protein A interacting C-terminal Sigma70_r4_2 PF08281.12 ABX11920.1 - 0.018 14.7 0.2 0.27 11.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.6 ABX11920.1 - 0.019 14.8 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Cyclin_C PF02984.19 ABX11920.1 - 0.042 13.9 0.0 2.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain Phage_terminase PF10668.9 ABX11920.1 - 0.05 13.6 0.3 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Phage terminase small subunit Baculo_ME53 PF06061.11 ABX11920.1 - 0.059 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 RB_B PF01857.20 ABX11920.1 - 0.11 12.5 0.2 0.19 11.8 0.2 1.5 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain HTH_23 PF13384.6 ABX11920.1 - 0.12 12.2 1.4 0.44 10.4 0.0 2.5 3 0 0 3 3 2 0 Homeodomain-like domain zf-FPG_IleRS PF06827.14 ABX11920.1 - 0.14 12.1 0.4 2.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-RRN7 PF11781.8 ABX11920.1 - 0.14 11.9 0.2 0.25 11.1 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF3921 PF13060.6 ABX11920.1 - 0.15 12.1 0.1 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) Auto_anti-p27 PF06677.12 ABX11920.1 - 0.16 12.2 1.4 0.28 11.4 1.4 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.6 ABX11920.1 - 0.17 11.3 1.3 0.87 9.1 1.3 2.0 1 1 0 1 1 1 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 ABX11920.1 - 0.22 11.3 0.9 0.44 10.3 0.9 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain Na_H_Exchanger PF00999.21 ABX11921.1 - 1.6e-35 122.6 47.8 2.2e-35 122.2 47.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Hemerythrin PF01814.23 ABX11922.1 - 2.3e-12 47.7 1.1 2.9e-12 47.3 0.5 1.5 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Nuf2 PF03800.14 ABX11922.1 - 0.029 14.5 1.5 0.086 13.0 0.6 1.9 1 1 1 2 2 2 0 Nuf2 family APS_kinase PF01583.20 ABX11923.1 - 1e-48 165.2 0.0 1.2e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 ABX11923.1 - 4.4e-06 26.9 0.0 5.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ABX11923.1 - 0.00012 21.4 0.0 0.00026 20.4 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 ABX11923.1 - 0.00022 21.8 0.0 0.00038 21.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ABX11923.1 - 0.0014 19.1 0.0 0.0023 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 ABX11923.1 - 0.0029 17.1 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 ABX11923.1 - 0.029 14.6 0.0 0.052 13.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain Ferrochelatase PF00762.19 ABX11923.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 1 0 1 1 1 0 Ferrochelatase Arf PF00025.21 ABX11923.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family CPT PF07931.12 ABX11923.1 - 0.17 11.7 0.1 3.2 7.6 0.1 2.3 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Inositol_P PF00459.25 ABX11924.1 - 4.5e-50 170.7 0.2 5.4e-50 170.4 0.2 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 ABX11924.1 - 0.059 12.8 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain CRPA PF05745.11 ABX11925.1 - 0.0047 17.0 2.6 0.0047 16.9 2.6 1.1 1 0 0 1 1 1 1 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF2953 PF11167.8 ABX11925.1 - 1.4 9.1 4.8 6.8 6.9 0.9 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2953) adh_short_C2 PF13561.6 ABX11926.1 - 1.1e-73 247.6 0.3 1.4e-73 247.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABX11926.1 - 1.7e-62 210.4 0.7 2e-62 210.1 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABX11926.1 - 8.6e-10 38.8 0.2 1.2e-09 38.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABX11926.1 - 0.031 13.8 0.6 0.07 12.6 0.6 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ABX11926.1 - 0.086 12.2 0.1 0.15 11.4 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Abi_2 PF07751.11 ABX11928.1 - 0.00088 19.6 0.6 0.0016 18.8 0.1 1.7 2 0 0 2 2 2 1 Abi-like protein DUF4145 PF13643.6 ABX11928.1 - 0.0012 18.9 0.7 0.0033 17.5 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4145) HEPN_Apea PF18739.1 ABX11928.1 - 0.0028 18.1 7.4 0.022 15.2 6.4 2.3 1 1 0 1 1 1 1 Apea-like HEPN HEPN_Swt1 PF18731.1 ABX11928.1 - 0.0039 17.5 0.2 0.0053 17.1 0.2 1.4 1 0 0 1 1 1 1 Swt1-like HEPN SNAD3 PF18749.1 ABX11928.1 - 0.016 14.4 3.5 0.019 14.2 3.5 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 HEPN_Cthe2314 PF18730.1 ABX11928.1 - 0.025 14.6 11.0 0.031 14.3 10.7 1.5 1 1 0 1 1 1 0 Cthe_2314-like HEPN HEPN_RiboL-PSP PF18735.1 ABX11928.1 - 0.057 13.3 12.7 0.088 12.7 12.5 1.7 1 1 0 1 1 1 0 RiboL-PSP-HEPN TipAS PF07739.13 ABX11928.1 - 0.06 13.9 0.5 0.09 13.3 0.5 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain DnaGprimase_HBD PF16730.5 ABX11928.1 - 0.24 11.5 7.2 6.5 6.9 4.6 2.8 2 1 0 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain Spectrin PF00435.21 ABX11928.1 - 1.3 9.6 7.2 4.1 8.0 2.7 2.4 2 1 0 2 2 2 0 Spectrin repeat Snf7 PF03357.21 ABX11929.1 - 2.5e-05 23.9 3.3 4.8e-05 23.0 3.3 1.4 1 1 0 1 1 1 1 Snf7 NAS PF03059.16 ABX11929.1 - 0.14 11.5 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein Importin_rep_6 PF18829.1 ABX11930.1 - 0.00027 21.0 0.8 0.087 13.0 0.1 2.4 2 0 0 2 2 2 2 Importin repeat 6 ASH PF15780.5 ABX11930.1 - 0.0022 18.1 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Occludin_ELL PF07303.13 ABX11930.1 - 0.23 12.2 7.8 0.92 10.3 0.3 2.3 2 0 0 2 2 2 0 Occludin homology domain NCBP3 PF10309.9 ABX11930.1 - 9.8 6.1 7.6 28 4.6 0.8 2.5 2 0 0 2 2 2 0 Nuclear cap-binding protein subunit 3 DUF1664 PF07889.12 ABX11931.1 - 0.00041 20.4 5.0 0.00081 19.4 5.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 ABX11931.1 - 0.00049 19.1 8.2 0.00067 18.6 8.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein HMMR_N PF15905.5 ABX11931.1 - 0.0012 18.4 9.5 0.0016 18.0 9.5 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal CREPT PF16566.5 ABX11931.1 - 0.0018 18.4 2.1 0.0024 18.0 2.1 1.2 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour AAA_13 PF13166.6 ABX11931.1 - 0.0028 16.4 4.5 0.0028 16.4 4.5 1.1 1 0 0 1 1 1 1 AAA domain Laminin_II PF06009.12 ABX11931.1 - 0.0038 17.2 5.9 0.0055 16.7 5.9 1.3 1 0 0 1 1 1 1 Laminin Domain II IFT57 PF10498.9 ABX11931.1 - 0.0057 15.7 4.8 0.0063 15.5 4.8 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF3450 PF11932.8 ABX11931.1 - 0.007 15.7 1.5 0.0075 15.6 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Flagellin_C PF00700.21 ABX11931.1 - 0.024 15.0 1.3 0.33 11.3 0.1 2.2 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region E2R135 PF11570.8 ABX11931.1 - 0.043 14.1 2.7 0.065 13.5 2.3 1.5 1 1 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Fmp27_WPPW PF10359.9 ABX11931.1 - 0.052 12.4 4.8 0.063 12.1 4.0 1.5 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Tropomyosin_1 PF12718.7 ABX11931.1 - 0.053 13.7 17.5 0.11 12.7 16.3 1.9 1 1 0 1 1 1 0 Tropomyosin like DUF2009 PF09418.10 ABX11931.1 - 0.056 12.5 1.2 0.064 12.3 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) TMPIT PF07851.13 ABX11931.1 - 0.059 12.6 1.1 0.07 12.4 1.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.9 ABX11931.1 - 0.078 12.1 3.4 0.087 11.9 3.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 ABX11931.1 - 0.095 13.2 10.0 4.5 7.8 6.8 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Prefoldin PF02996.17 ABX11931.1 - 0.11 12.5 7.3 0.68 9.9 2.5 2.3 1 1 0 2 2 2 0 Prefoldin subunit DUF724 PF05266.14 ABX11931.1 - 0.11 12.3 7.9 0.12 12.2 6.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Rx_N PF18052.1 ABX11931.1 - 0.12 12.6 2.6 0.21 11.9 2.6 1.4 1 0 0 1 1 1 0 Rx N-terminal domain FAM76 PF16046.5 ABX11931.1 - 0.19 11.0 5.1 0.22 10.8 5.1 1.1 1 0 0 1 1 1 0 FAM76 protein Syntaxin_2 PF14523.6 ABX11931.1 - 0.22 11.9 5.4 7.3 7.0 0.2 2.5 1 1 1 2 2 2 0 Syntaxin-like protein SpecificRecomb PF10136.9 ABX11931.1 - 0.23 9.7 0.1 0.24 9.6 0.1 1.0 1 0 0 1 1 1 0 Site-specific recombinase COG2 PF06148.11 ABX11931.1 - 0.31 11.1 3.9 0.45 10.6 3.3 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 YabA PF06156.13 ABX11931.1 - 0.4 11.3 5.9 1.4 9.6 5.1 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Spectrin PF00435.21 ABX11931.1 - 0.47 11.0 6.1 3.3 8.2 5.9 2.3 1 1 1 2 2 2 0 Spectrin repeat UPF0242 PF06785.11 ABX11931.1 - 0.52 10.4 7.3 0.62 10.1 7.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 ABX11931.1 - 0.85 10.1 4.0 7.6 7.1 3.9 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Csm1_N PF18504.1 ABX11931.1 - 0.9 9.9 9.5 2 8.8 7.6 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain CSRNP_N PF16019.5 ABX11931.1 - 1.3 8.9 3.6 1.8 8.4 3.6 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Nas2_N PF18265.1 ABX11931.1 - 3.2 7.8 8.6 3.9 7.5 0.1 3.4 1 1 2 3 3 3 0 Nas2 N_terminal domain FlaC_arch PF05377.11 ABX11931.1 - 5.1 7.6 10.3 9 6.8 4.4 2.8 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF2674 PF10879.8 ABX11932.1 - 0.018 14.6 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) HTH_45 PF14947.6 ABX11933.1 - 1.2e-08 34.8 0.0 1.5e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_27 PF13463.6 ABX11933.1 - 2.1e-06 28.1 0.0 3.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 ABX11933.1 - 7.6e-06 25.7 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 MarR family Mrr_N PF14338.6 ABX11933.1 - 0.00022 21.3 0.0 0.0028 17.7 0.0 2.0 1 1 1 2 2 2 1 Mrr N-terminal domain DUF4364 PF14277.6 ABX11933.1 - 0.00054 19.7 0.0 0.00063 19.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) DUF1495 PF07381.11 ABX11933.1 - 0.0024 17.6 0.0 0.005 16.6 0.0 1.5 1 1 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) RNA_pol_Rpc34 PF05158.12 ABX11933.1 - 0.0033 16.9 0.1 0.0042 16.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_20 PF12840.7 ABX11933.1 - 0.014 15.4 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 ABX11933.1 - 0.024 14.5 0.1 0.039 13.8 0.1 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 ABX11933.1 - 0.048 13.8 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) MarR PF01047.22 ABX11933.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 MarR family PadR PF03551.14 ABX11933.1 - 0.093 12.7 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_34 PF13601.6 ABX11933.1 - 0.096 12.9 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain AlphaC_N PF08829.10 ABX11934.1 - 0.011 15.7 0.2 1.3 9.0 0.1 3.0 2 1 1 3 3 3 0 Alpha C protein N terminal HTH_24 PF13412.6 ABX11934.1 - 0.02 14.4 0.1 0.07 12.7 0.0 2.0 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_micro PF17007.5 ABX11934.1 - 0.064 12.1 0.1 0.085 11.7 0.1 1.1 1 0 0 1 1 1 0 HTH-like BPL_LplA_LipB PF03099.19 ABX11935.1 - 0.048 13.6 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family HECT_2 PF09814.9 ABX11935.1 - 0.067 12.0 0.0 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SKG6 PF08693.10 ABX11936.1 - 0.015 14.7 0.7 0.015 14.7 0.7 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Phage_holin_2_4 PF16082.5 ABX11936.1 - 8.5 6.2 6.1 3 7.6 0.9 2.0 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like Fer4_12 PF13353.6 ABX11937.1 - 1.1e-13 51.6 0.1 2.7e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ABX11937.1 - 5.1e-13 49.2 0.1 8.6e-13 48.5 0.1 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 ABX11937.1 - 6.5e-09 36.4 0.0 8.1e-09 36.1 0.0 1.3 1 1 0 1 1 1 1 Radical SAM superfamily GTP_cyclohydroI PF01227.22 ABX11938.1 - 2e-64 216.3 0.0 2.2e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 ABX11938.1 - 0.0084 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein OST-HTH PF12872.7 ABX11938.1 - 0.037 13.9 0.1 0.48 10.3 0.1 2.5 2 1 0 2 2 2 0 OST-HTH/LOTUS domain QueC PF06508.13 ABX11940.1 - 7.5e-49 166.1 0.0 8.6e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 ABX11940.1 - 0.00014 21.3 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.21 ABX11940.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 ABX11940.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.16 ABX11940.1 - 0.057 12.2 0.1 0.079 11.7 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase GHMP_kinases_N PF00288.26 ABX11941.1 - 4e-13 49.4 4.0 8.7e-13 48.3 4.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ABX11941.1 - 1.9e-10 41.0 0.0 3.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal ATP_bind_1 PF03029.17 ABX11942.1 - 1.6e-56 191.8 0.0 1.8e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 ABX11942.1 - 0.00054 20.0 0.0 0.00078 19.5 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 ABX11942.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain CLP1_P PF16575.5 ABX11942.1 - 0.0021 17.9 0.1 0.43 10.3 0.1 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF2075 PF09848.9 ABX11942.1 - 0.009 15.3 0.1 0.028 13.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Imm61 PF15598.6 ABX11942.1 - 0.022 14.7 0.0 0.056 13.3 0.0 1.6 1 1 0 1 1 1 0 Immunity protein 61 MeaB PF03308.16 ABX11942.1 - 0.029 13.4 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 ABX11942.1 - 0.034 14.1 0.1 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ParA PF10609.9 ABX11942.1 - 0.069 12.6 0.5 1.4 8.3 0.5 2.2 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase GTP_EFTU PF00009.27 ABX11942.1 - 0.075 12.6 0.0 1.5 8.4 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SRP54 PF00448.22 ABX11942.1 - 0.09 12.4 0.1 2 8.0 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 ABX11942.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ABX11942.1 - 0.18 11.0 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 ABX11942.1 - 0.18 12.3 0.1 0.29 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 ABX11942.1 - 0.2 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase LPG_synthase_TM PF03706.13 ABX11943.1 - 2.5e-23 83.1 14.4 3.3e-23 82.7 14.4 1.2 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region CPP1-like PF11833.8 ABX11943.1 - 1.2 8.7 4.5 3.1 7.4 4.5 1.6 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like adh_short PF00106.25 ABX11944.1 - 5.9e-59 198.8 0.1 7.4e-59 198.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABX11944.1 - 3.2e-40 138.1 0.0 4e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABX11944.1 - 9.7e-17 61.4 0.1 1.2e-16 61.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ABX11944.1 - 0.00068 18.9 0.1 0.0009 18.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ABX11944.1 - 0.0035 16.8 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 ABX11944.1 - 0.006 16.0 0.1 0.012 15.0 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 ABX11944.1 - 0.0062 16.5 0.0 0.018 14.9 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ABX11944.1 - 0.0066 16.7 0.3 0.013 15.7 0.2 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DFP PF04127.15 ABX11944.1 - 0.014 15.2 0.1 0.034 14.0 0.1 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_7 PF13241.6 ABX11944.1 - 0.021 15.3 0.3 0.074 13.5 0.2 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF1776 PF08643.10 ABX11944.1 - 0.044 13.2 0.0 0.1 11.9 0.0 1.5 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.8 ABX11944.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PTH2 PF01981.16 ABX11944.1 - 0.13 12.5 0.1 0.32 11.3 0.1 1.6 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Shikimate_DH PF01488.20 ABX11944.1 - 0.14 12.3 0.2 0.28 11.2 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase G10 PF01125.17 ABX11945.1 - 0.0028 17.4 2.0 0.89 9.3 0.1 2.2 1 1 1 2 2 2 2 G10 protein PH_14 PF17787.1 ABX11945.1 - 0.032 14.1 0.7 0.055 13.3 0.4 1.6 1 1 1 2 2 2 0 PH domain OrfB_Zn_ribbon PF07282.11 ABX11946.1 - 0.0042 17.0 2.3 0.11 12.5 0.1 2.3 2 0 0 2 2 2 1 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 ABX11946.1 - 0.0044 16.5 0.6 0.2 11.2 0.0 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding zf-Mss51 PF13824.6 ABX11946.1 - 0.037 14.1 1.3 0.092 12.9 1.3 1.9 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Rpr2 PF04032.16 ABX11946.1 - 0.11 12.8 0.3 0.11 12.8 0.3 1.6 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TFIIS_C PF01096.18 ABX11946.1 - 0.26 11.2 3.0 6.4 6.7 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Pox_Ag35 PF03286.14 ABX11946.1 - 0.42 10.4 5.6 0.48 10.2 5.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_L32p PF01783.23 ABX11946.1 - 0.58 10.5 0.0 0.58 10.5 0.0 2.6 3 0 0 3 3 3 0 Ribosomal L32p protein family Glyco_trans_1_3 PF13528.6 ABX11947.1 - 0.0002 20.7 0.0 0.21 10.8 0.0 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 1 T3SchapCesA PF11439.8 ABX11947.1 - 0.28 11.3 4.8 0.24 11.6 0.6 2.9 3 0 0 3 3 3 0 Type III secretion system filament chaperone CesA DUF5365 PF17326.2 ABX11948.1 - 0.67 10.4 6.0 1.2 9.5 0.4 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5365) PAPS_reduct PF01507.19 ABX11949.1 - 8e-42 143.2 0.0 1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family FlaC_arch PF05377.11 ABX11949.1 - 0.043 14.2 0.1 5.4 7.5 0.0 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CSN5_C PF18323.1 ABX11949.1 - 0.064 14.2 0.0 0.1 13.5 0.0 1.4 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain ATP-sulfurylase PF01747.17 ABX11950.1 - 9.9e-83 276.8 0.3 2.2e-82 275.7 0.2 1.6 2 0 0 2 2 2 1 ATP-sulfurylase PUA_2 PF14306.6 ABX11950.1 - 3.5e-47 160.0 0.0 7.2e-47 159.0 0.0 1.6 1 1 0 1 1 1 1 PUA-like domain DsbC_N PF10411.9 ABX11951.1 - 0.12 11.8 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus DUF3991 PF13154.6 ABX11951.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3991) HhH-GPD PF00730.25 ABX11952.1 - 1.2e-25 90.1 0.6 2.2e-25 89.2 0.1 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ABX11952.1 - 2.2e-08 33.5 0.0 5.2e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ABX11952.1 - 0.00075 20.1 0.2 0.28 11.8 0.0 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix domain AGOG PF09171.10 ABX11952.1 - 0.0012 18.2 0.6 0.0056 16.0 0.0 2.0 2 0 0 2 2 2 1 N-glycosylase/DNA lyase DUF2400 PF09674.10 ABX11952.1 - 0.0035 17.4 0.1 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2400) HHH_2 PF12826.7 ABX11952.1 - 0.082 13.0 0.0 5.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF521 PF04412.13 ABX11953.1 - 3.5e-111 371.7 0.1 4.6e-111 371.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Fer4_12 PF13353.6 ABX11953.1 - 0.0042 17.4 0.8 0.0073 16.6 0.8 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF126 PF01989.16 ABX11954.1 - 2.7e-31 107.2 0.1 5.1e-31 106.3 0.1 1.4 1 0 0 1 1 1 1 Aconitase X swivel domain FbpA PF05833.11 ABX11955.1 - 1.7e-39 135.9 13.3 2.2e-39 135.5 13.3 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 ABX11955.1 - 1.3e-23 83.7 0.1 5.3e-23 81.8 0.0 2.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain DUF727 PF05303.12 ABX11955.1 - 0.065 13.3 1.5 0.3 11.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF727) Tweety PF04906.13 ABX11955.1 - 1.1 7.8 8.6 2.1 6.9 1.4 2.2 1 1 0 2 2 2 0 Tweety PKcGMP_CC PF16808.5 ABX11955.1 - 2.5 8.0 10.1 0.057 13.3 2.2 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4366 PF14283.6 ABX11956.1 - 0.00096 19.2 0.3 0.0021 18.1 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) 7TM_GPCR_Srsx PF10320.9 ABX11956.1 - 0.0037 16.7 2.1 0.0054 16.1 2.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PhoLip_ATPase_C PF16212.5 ABX11956.1 - 0.0039 17.0 0.2 0.0047 16.7 0.2 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Trypan_PARP PF05887.11 ABX11956.1 - 0.011 15.7 7.0 0.017 15.1 7.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF21 PF01595.20 ABX11956.1 - 0.02 14.6 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain MFS_1_like PF12832.7 ABX11956.1 - 0.021 13.7 1.2 0.031 13.1 1.2 1.4 1 1 0 1 1 1 0 MFS_1 like family NrsF PF06532.11 ABX11956.1 - 0.042 13.6 0.2 0.052 13.2 0.2 1.1 1 0 0 1 1 1 0 Negative regulator of sigma F Keratin_assoc PF09775.9 ABX11956.1 - 0.045 13.4 1.1 0.07 12.8 1.1 1.2 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Colicin_V PF02674.16 ABX11956.1 - 0.079 12.9 2.8 0.067 13.2 1.6 1.4 1 1 0 1 1 1 0 Colicin V production protein DUF543 PF04418.12 ABX11956.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF543) DUF202 PF02656.15 ABX11956.1 - 0.46 11.0 4.4 0.88 10.1 4.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) ATP_synt_H PF05493.13 ABX11956.1 - 1.8 9.1 5.2 4.9 7.7 5.2 1.7 1 1 0 1 1 1 0 ATP synthase subunit H Methyltransf_31 PF13847.6 ABX11957.1 - 1.2e-14 54.4 0.9 2.3e-14 53.5 0.5 1.5 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.19 ABX11957.1 - 1.2e-12 48.1 0.4 1.4e-12 47.8 0.4 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 ABX11957.1 - 5.9e-10 39.0 2.9 7.8e-10 38.6 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 ABX11957.1 - 1.1e-09 38.3 1.0 1.4e-09 38.1 1.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX11957.1 - 4.5e-09 36.9 0.0 8.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABX11957.1 - 1.1e-08 34.7 0.5 1.6e-08 34.2 0.5 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ABX11957.1 - 4.1e-08 33.0 0.2 9.2e-08 31.8 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ABX11957.1 - 7.7e-07 28.7 0.3 3e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 Putative methyltransferase GCD14 PF08704.10 ABX11957.1 - 8.4e-07 28.9 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_3 PF01596.17 ABX11957.1 - 2.5e-06 26.8 0.2 3e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_11 PF08241.12 ABX11957.1 - 3.7e-06 27.5 0.0 8.6e-06 26.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 ABX11957.1 - 3.7e-06 26.4 0.3 8e-06 25.3 0.1 1.7 1 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 ABX11957.1 - 6.6e-06 25.9 0.0 9.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 ABX11957.1 - 1.3e-05 25.0 0.2 0.00015 21.5 0.1 2.4 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 ABX11957.1 - 8.8e-05 23.2 0.1 0.00017 22.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain TrmK PF04816.12 ABX11957.1 - 9.3e-05 22.0 0.9 0.00014 21.5 0.9 1.2 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_15 PF09445.10 ABX11957.1 - 0.00018 21.1 0.3 0.00035 20.2 0.2 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase AviRa PF11599.8 ABX11957.1 - 0.0002 20.9 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa FtsJ PF01728.19 ABX11957.1 - 0.00028 21.1 0.0 0.032 14.4 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 ABX11957.1 - 0.0015 18.2 0.1 0.013 15.2 0.0 2.0 1 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F GidB PF02527.15 ABX11957.1 - 0.0023 17.3 0.2 0.003 16.9 0.2 1.3 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.6 ABX11957.1 - 0.0027 17.7 0.2 0.004 17.1 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 ABX11957.1 - 0.0033 18.4 0.0 0.0048 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 ABX11957.1 - 0.0037 16.8 0.4 0.0089 15.6 0.4 1.7 1 1 0 1 1 1 1 Histone methylation protein DOT1 Met_10 PF02475.16 ABX11957.1 - 0.0043 16.8 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_5 PF01795.19 ABX11957.1 - 0.0047 16.5 0.0 0.0089 15.6 0.0 1.4 1 1 0 1 1 1 1 MraW methylase family TRM PF02005.16 ABX11957.1 - 0.0085 15.3 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase N6_Mtase PF02384.16 ABX11957.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase RrnaAD PF00398.20 ABX11957.1 - 0.028 13.5 0.1 0.042 12.9 0.1 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 ABX11957.1 - 0.03 14.2 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 ABX11957.1 - 0.032 13.7 0.2 0.081 12.4 0.1 1.7 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Spermine_synth PF01564.17 ABX11957.1 - 0.052 13.0 0.5 0.099 12.0 0.2 1.7 1 1 1 2 2 2 0 Spermine/spermidine synthase domain TP_methylase PF00590.20 ABX11958.1 - 1.5e-55 188.5 0.0 1.7e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TP_methylase PF00590.20 ABX11959.1 - 4.1e-48 164.1 0.1 5e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.21 ABX11959.1 - 0.0017 18.7 0.1 0.0046 17.3 0.1 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Cyt_b-c1_8 PF10890.8 ABX11959.1 - 0.045 14.1 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Asp_Glu_race PF01177.22 ABX11960.1 - 6.5e-20 71.9 0.0 8.1e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Snf7 PF03357.21 ABX11961.1 - 0.00078 19.1 8.1 0.0018 17.9 8.1 1.6 1 1 0 1 1 1 1 Snf7 KASH_CCD PF14662.6 ABX11961.1 - 0.0027 17.6 2.4 0.0027 17.6 2.4 1.7 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH BLOC1S3 PF15753.5 ABX11961.1 - 0.019 15.1 0.6 0.019 15.1 0.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Serine_rich PF08824.10 ABX11961.1 - 0.027 14.5 2.6 0.037 14.0 1.8 1.5 1 1 0 1 1 1 0 Serine rich protein interaction domain Baculo_PEP_C PF04513.12 ABX11961.1 - 0.027 14.5 2.7 0.72 9.9 0.5 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Duo1 PF08651.10 ABX11961.1 - 0.07 12.9 0.8 0.42 10.4 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 Cas_Cas7 PF05107.12 ABX11961.1 - 0.071 12.6 0.1 0.097 12.2 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cas7 Atg14 PF10186.9 ABX11961.1 - 0.11 11.6 1.2 0.16 11.0 1.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 ABX11961.1 - 0.11 11.0 1.3 0.14 10.7 1.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.11 ABX11961.1 - 0.12 12.6 3.4 0.07 13.4 1.4 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Flagellin_C PF00700.21 ABX11961.1 - 0.9 9.9 5.8 3.1 8.2 0.9 2.8 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF948 PF06103.11 ABX11961.1 - 0.98 9.7 5.5 8.8 6.7 1.3 3.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 ABX11961.1 - 1.3 9.5 4.4 17 6.0 0.5 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF745 PF05335.13 ABX11961.1 - 6.7 6.4 9.2 1.9 8.2 1.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Glycos_transf_2 PF00535.26 ABX11962.1 - 4.2e-35 121.0 0.0 8.1e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 GtrA PF04138.14 ABX11962.1 - 1.7e-23 83.1 9.1 3.5e-23 82.1 9.1 1.6 1 0 0 1 1 1 1 GtrA-like protein Glyco_tranf_2_3 PF13641.6 ABX11962.1 - 9.9e-10 38.7 0.0 1.4e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1279 PF06916.13 ABX11962.1 - 0.025 15.1 0.2 0.07 13.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) HGTP_anticodon PF03129.20 ABX11963.1 - 1.3e-16 60.5 0.2 3.7e-16 59.1 0.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ABX11963.1 - 8.8e-11 42.1 0.2 8.9e-10 38.8 0.2 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zf-RRPl_C4 PF17026.5 ABX11963.1 - 0.032 14.3 0.3 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 ABX11963.1 - 0.07 13.3 0.2 15 5.8 0.0 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 ABX11963.1 - 0.16 11.9 2.7 9.3 6.3 0.4 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 ABX11963.1 - 0.17 12.6 1.9 0.69 10.7 1.5 2.1 1 1 1 2 2 2 0 zinc-ribbon family zf-H2C2_2 PF13465.6 ABX11963.1 - 0.44 11.1 1.7 31 5.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zinc_ribbon_9 PF14369.6 ABX11963.1 - 0.7 10.2 2.4 5.9 7.2 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon zinc_ribbon_5 PF13719.6 ABX11963.1 - 1.4 8.8 7.7 2 8.2 1.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain AP_endonuc_2 PF01261.24 ABX11964.1 - 5.3e-35 120.8 0.0 1.1e-34 119.7 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DNA_primase_lrg PF04104.14 ABX11965.1 - 4e-25 88.7 0.0 1.1e-24 87.3 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Med5 PF08689.10 ABX11965.1 - 0.0063 14.4 0.2 0.0076 14.1 0.2 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 DNA_primase_S PF01896.19 ABX11966.1 - 2.3e-15 57.1 0.6 3.3e-14 53.3 0.6 2.2 1 1 0 1 1 1 1 DNA primase small subunit PolC_DP2 PF03833.13 ABX11966.1 - 0.71 7.7 4.1 0.99 7.2 4.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 UPF0182 PF03699.13 ABX11967.1 - 9.1e-34 116.7 14.0 1.2e-32 113.0 14.0 2.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0182) GATase PF00117.28 ABX11968.1 - 5.9e-23 81.6 0.0 6.8e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ABX11968.1 - 4.8e-08 33.0 0.0 1.5e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 ABX11968.1 - 0.095 12.5 0.1 2.4 7.9 0.0 2.4 1 1 2 3 3 3 0 SNO glutamine amidotransferase family TPR_1 PF00515.28 ABX11969.1 - 2.1e-19 68.4 17.9 1.8e-10 40.2 0.3 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ABX11969.1 - 8.2e-18 63.0 9.4 1.7e-07 30.8 0.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 ABX11969.1 - 2.6e-15 55.3 10.0 4.7e-07 29.5 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 ABX11969.1 - 2.3e-14 52.6 8.6 0.0001 22.4 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ABX11969.1 - 6.1e-12 45.0 6.7 7.2e-06 25.6 0.1 3.7 1 1 2 3 3 3 3 TPR repeat TPR_12 PF13424.6 ABX11969.1 - 3e-11 43.4 0.2 1e-05 25.7 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 ABX11969.1 - 2.3e-08 34.1 0.0 1.9e-05 24.7 0.0 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ABX11969.1 - 3.4e-08 33.7 0.0 0.031 15.1 0.0 3.5 1 1 3 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 ABX11969.1 - 1.6e-07 30.9 0.1 0.0001 22.1 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ABX11969.1 - 1.7e-07 31.6 0.4 0.0011 19.4 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ABX11969.1 - 3e-07 31.0 0.0 0.83 10.4 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 ABX11969.1 - 7.9e-07 29.3 1.6 7.4 7.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Peptidase_C39_2 PF13529.6 ABX11969.1 - 0.00011 22.8 0.0 0.00043 20.9 0.0 2.0 1 1 0 1 1 1 1 Peptidase_C39 like family TPR_10 PF13374.6 ABX11969.1 - 0.00077 19.3 0.1 0.023 14.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 ABX11969.1 - 0.0013 18.7 1.7 12 6.0 0.0 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 ABX11969.1 - 0.0089 16.1 1.2 0.091 12.9 0.1 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 ABX11969.1 - 0.041 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 MalT-like TPR region Peptidase_C70 PF12385.8 ABX11969.1 - 0.043 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 ANAPC3 PF12895.7 ABX11969.1 - 0.08 13.2 3.9 3.3 8.0 1.9 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 ABX11969.1 - 0.11 12.5 1.9 23 5.0 0.1 3.4 3 1 1 4 4 4 0 Mad3/BUB1 homology region 1 RGS PF00615.19 ABX11969.1 - 0.19 12.0 2.4 2.1 8.6 2.4 2.3 1 1 0 1 1 1 0 Regulator of G protein signaling domain zinc_ribbon_4 PF13717.6 ABX11970.1 - 0.00082 19.2 3.2 0.0065 16.4 3.2 2.1 1 1 0 1 1 1 1 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 ABX11970.1 - 0.0025 17.7 1.2 0.0036 17.2 1.2 1.2 1 0 0 1 1 1 1 Putative transposase DNA-binding domain IBR PF01485.21 ABX11970.1 - 0.0027 17.9 0.9 0.0027 17.9 0.9 1.4 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain CpXC PF14353.6 ABX11970.1 - 0.009 16.0 2.5 0.032 14.3 0.1 2.0 1 1 1 2 2 2 1 CpXC protein YacG PF03884.14 ABX11970.1 - 0.019 14.7 0.3 3.2 7.6 0.0 2.2 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Ogr_Delta PF04606.12 ABX11970.1 - 0.027 14.5 0.3 7.7 6.6 0.1 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger HypA PF01155.19 ABX11970.1 - 0.048 13.7 0.3 0.05 13.6 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S27e PF01667.17 ABX11970.1 - 0.053 13.2 3.0 0.15 11.8 3.0 1.7 1 1 0 1 1 1 0 Ribosomal protein S27 Zn_Tnp_IS91 PF14319.6 ABX11970.1 - 0.064 13.3 0.1 0.064 13.3 0.1 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-LSD1 PF06943.12 ABX11970.1 - 0.084 12.7 0.8 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 LSD1 zinc finger zf-H2C2_5 PF13909.6 ABX11970.1 - 0.14 12.0 0.4 0.14 12.0 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain ORC4_C PF14629.6 ABX11970.1 - 0.16 11.3 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus zf-ribbon_3 PF13248.6 ABX11970.1 - 0.21 11.0 7.0 2.2 7.8 7.0 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-Di19 PF05605.12 ABX11970.1 - 0.23 11.8 3.4 0.66 10.3 0.5 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding UPF0547 PF10571.9 ABX11970.1 - 0.24 11.5 5.2 4.7 7.4 0.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_7 PF02591.15 ABX11970.1 - 0.38 11.0 3.8 4.3 7.6 0.1 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-ISL3 PF14690.6 ABX11970.1 - 0.46 11.2 3.5 8.1 7.2 3.5 2.1 1 1 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_5 PF13719.6 ABX11970.1 - 0.5 10.2 3.7 1.2 9.0 3.7 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 ABX11970.1 - 0.88 9.9 6.6 25 5.2 7.0 2.2 1 1 1 2 2 2 0 zinc-ribbon Zn-ribbon_8 PF09723.10 ABX11970.1 - 1.2 9.3 5.6 10 6.3 5.6 2.1 1 1 0 1 1 1 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 ABX11970.1 - 4.4 7.3 7.9 2.1 8.3 0.9 2.4 2 1 0 2 2 2 0 PhnA Zinc-Ribbon Ribosomal_S6e PF01092.19 ABX11971.1 - 6.6e-26 90.7 0.2 7.6e-26 90.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S6e GTP_EFTU PF00009.27 ABX11972.1 - 6.7e-30 104.1 0.0 2.3e-29 102.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 ABX11972.1 - 1.9e-26 92.1 0.4 1.7e-25 89.1 0.1 2.5 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal MMR_HSR1 PF01926.23 ABX11972.1 - 1.7e-05 24.8 0.0 4.4e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ABX11972.1 - 2.3e-05 24.7 1.0 5.7e-05 23.4 0.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 ABX11972.1 - 0.00056 19.9 0.3 0.017 15.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 ABX11972.1 - 0.03 13.9 0.1 2 7.9 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 ABX11972.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.7 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain ILEI PF15711.5 ABX11972.1 - 0.13 12.7 0.0 3.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Interleukin-like EMT inducer HypA PF01155.19 ABX11972.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NOB1_Zn_bind PF08772.11 ABX11972.1 - 0.18 12.0 1.2 0.43 10.8 0.1 2.1 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.10 ABX11972.1 - 1.3 9.2 3.4 3 8.0 3.4 1.6 1 1 0 1 1 1 0 Zinc ribbon domain PIN_9 PF18477.1 ABX11973.1 - 1.5e-11 44.6 0.1 1.7e-11 44.4 0.1 1.0 1 0 0 1 1 1 1 PIN like domain Fcf1 PF04900.12 ABX11973.1 - 0.033 14.6 0.0 0.044 14.2 0.0 1.2 1 0 0 1 1 1 0 Fcf1 DUF3842 PF12953.7 ABX11973.1 - 0.035 14.5 0.1 2.9 8.3 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3842) PIN PF01850.21 ABX11973.1 - 0.044 14.3 0.1 0.051 14.1 0.1 1.3 1 1 0 1 1 1 0 PIN domain PBP PF01161.20 ABX11974.1 - 2.1e-36 125.1 0.0 2.4e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Phage_Cox PF10743.9 ABX11974.1 - 0.094 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Regulatory phage protein cox Luciferase_N PF05295.11 ABX11974.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain STT3 PF02516.14 ABX11975.1 - 7e-38 130.8 27.5 1.4e-37 129.8 27.4 1.4 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 ABX11975.1 - 0.00017 21.9 12.7 0.00017 21.9 12.7 3.3 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF5392 PF17370.2 ABX11975.1 - 6.8 6.8 8.8 0.55 10.3 0.2 3.2 3 1 0 3 3 3 0 Family of unknown function (DUF5392) Nop10p PF04135.12 ABX11976.1 - 1.7e-24 85.6 3.6 1.7e-24 85.6 3.6 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family RecR PF02132.15 ABX11976.1 - 0.00035 20.1 1.2 0.00042 19.8 1.2 1.2 1 0 0 1 1 1 1 RecR protein PolC_DP2 PF03833.13 ABX11976.1 - 0.0092 13.9 0.4 0.0092 13.9 0.4 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 NOB1_Zn_bind PF08772.11 ABX11976.1 - 0.011 15.9 0.7 0.011 15.9 0.7 1.2 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF1272 PF06906.11 ABX11976.1 - 0.014 15.5 0.6 0.015 15.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf_C2H2_10 PF18414.1 ABX11976.1 - 3.2 7.4 7.1 1.1 8.8 1.5 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger EIF_2_alpha PF07541.12 ABX11977.1 - 2.9e-18 66.0 0.3 7e-18 64.8 0.3 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 ABX11977.1 - 5.6e-11 42.6 0.1 2.9e-10 40.3 0.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.9 ABX11977.1 - 0.017 15.7 0.1 0.073 13.7 0.1 2.1 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 S1_2 PF13509.6 ABX11977.1 - 0.051 13.6 0.1 0.91 9.6 0.0 2.8 2 0 0 2 2 2 0 S1 domain Arm-DNA-bind_2 PF12167.8 ABX11977.1 - 0.056 13.4 0.4 0.21 11.6 0.1 2.1 2 0 0 2 2 2 0 Arm DNA-binding domain CobA_CobO_BtuR PF02572.15 ABX11978.1 - 5e-63 212.4 0.4 5.6e-63 212.3 0.4 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_14 PF13173.6 ABX11978.1 - 0.004 17.2 0.6 0.011 15.8 0.1 1.7 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 ABX11978.1 - 0.13 12.3 3.7 1.3 9.1 1.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 ABX11978.1 - 0.16 11.5 1.7 0.72 9.4 1.7 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ABX11978.1 - 0.44 10.3 2.3 2.2 8.0 0.2 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein GATase_3 PF07685.14 ABX11979.1 - 1.5e-41 142.2 0.1 2.1e-41 141.7 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 ABX11979.1 - 1.3e-19 70.5 0.2 4.7e-19 68.7 0.0 2.0 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 ABX11979.1 - 2.2e-15 57.0 0.6 9.3e-10 38.7 0.0 2.6 1 1 0 2 2 2 2 AAA domain SNO PF01174.19 ABX11979.1 - 7.5e-06 25.9 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 SNO glutamine amidotransferase family SRP54 PF00448.22 ABX11979.1 - 0.0048 16.5 0.3 0.2 11.2 0.1 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CTP_synth_N PF06418.14 ABX11979.1 - 0.0064 15.8 0.2 0.02 14.2 0.0 1.8 2 0 0 2 2 2 1 CTP synthase N-terminus Fer4_NifH PF00142.18 ABX11979.1 - 0.052 13.0 0.7 0.12 11.8 0.2 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Peptidase_S51 PF03575.17 ABX11979.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 ArsA_ATPase PF02374.15 ABX11979.1 - 0.12 11.6 0.9 0.33 10.1 0.1 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase CBP_BcsQ PF06564.12 ABX11979.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ ParA PF10609.9 ABX11979.1 - 0.14 11.6 0.1 0.51 9.8 0.0 1.9 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase DJ-1_PfpI PF01965.24 ABX11979.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family NTPase_1 PF03266.15 ABX11979.1 - 0.18 11.7 1.0 1.2 9.0 0.2 2.3 2 0 0 2 2 2 0 NTPase CbiC PF02570.15 ABX11980.1 - 2.5e-72 242.7 0.4 2.8e-72 242.5 0.4 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase CbiX PF01903.17 ABX11981.1 - 1.2e-34 118.8 0.0 4.9e-16 59.0 0.0 2.1 2 0 0 2 2 2 2 CbiX CbiK PF06180.11 ABX11981.1 - 7.1e-07 28.8 0.8 8.7e-07 28.5 0.8 1.2 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Ferrochelatase PF00762.19 ABX11981.1 - 0.0026 16.9 0.0 0.17 10.9 0.0 2.0 1 1 1 2 2 2 2 Ferrochelatase AAA_15 PF13175.6 ABX11981.1 - 0.028 14.1 2.3 0.035 13.8 2.3 1.2 1 0 0 1 1 1 0 AAA ATPase domain CbiG_N PF11760.8 ABX11982.1 - 6.8e-35 118.9 0.2 1.1e-34 118.2 0.2 1.4 1 0 0 1 1 1 1 Cobalamin synthesis G N-terminal CbiG_C PF01890.16 ABX11982.1 - 6.3e-27 94.4 0.1 1.6e-26 93.2 0.0 1.7 2 0 0 2 2 2 1 Cobalamin synthesis G C-terminus CbiG_mid PF11761.8 ABX11982.1 - 3.2e-18 65.6 0.0 2e-17 63.1 0.0 2.3 3 0 0 3 3 3 1 Cobalamin biosynthesis central region SpoU_sub_bind PF08032.12 ABX11982.1 - 0.025 14.8 0.0 0.079 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding CbiD PF01888.17 ABX11983.1 - 6.2e-93 310.7 4.8 7.9e-93 310.4 4.8 1.1 1 0 0 1 1 1 1 CbiD DUF3042 PF11240.8 ABX11983.1 - 0.069 13.2 0.1 0.069 13.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) Epimerase PF01370.21 ABX11984.1 - 4.1e-10 39.5 0.0 3.8e-09 36.4 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABX11984.1 - 5.4e-10 39.5 0.0 9.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ABX11984.1 - 1.6e-09 37.2 0.1 4.1e-08 32.6 0.1 2.3 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ABX11984.1 - 1e-05 24.9 1.6 0.34 10.0 0.0 3.9 1 1 2 4 4 4 3 Male sterility protein RmlD_sub_bind PF04321.17 ABX11984.1 - 0.00014 21.1 0.0 0.001 18.2 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 ABX11984.1 - 0.00031 20.4 1.6 0.00056 19.5 1.6 1.4 1 1 0 1 1 1 1 NmrA-like family DDE_Tnp_1_3 PF13612.6 ABX11984.1 - 0.046 13.7 0.2 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Transposase DDE domain BDV_M PF16520.5 ABX11984.1 - 0.13 12.6 2.7 0.45 10.9 0.3 2.5 2 1 0 2 2 2 0 ssRNA-binding matrix protein of Bornaviridae S-AdoMet_synt_C PF02773.16 ABX11985.1 - 2.9e-70 234.6 0.1 9.9e-70 232.9 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ABX11985.1 - 3.2e-49 166.2 0.2 7e-48 161.8 0.0 2.2 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ABX11985.1 - 2.7e-40 137.1 0.9 5.3e-40 136.1 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 ABX11985.1 - 0.00044 19.2 1.4 0.078 11.8 0.2 2.2 1 1 0 2 2 2 2 S-adenosylmethionine synthetase (AdoMet synthetase) LSM PF01423.22 ABX11986.1 - 5.3e-20 70.9 1.7 5.9e-20 70.7 1.7 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ABX11986.1 - 0.0094 15.6 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Hfq protein BrnA_antitoxin PF14384.6 ABX11986.1 - 0.067 13.7 0.2 0.12 12.8 0.2 1.4 1 0 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system MHC_I_3 PF16497.5 ABX11986.1 - 0.13 11.7 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 MHC-I family domain Rad51 PF08423.11 ABX11987.1 - 9.3e-27 93.9 0.1 1.1e-26 93.7 0.1 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 ABX11987.1 - 1.6e-09 37.4 5.9 1.1e-08 34.7 1.2 2.2 2 0 0 2 2 2 2 KaiC AAA_24 PF13479.6 ABX11987.1 - 2.1e-08 34.1 0.2 3.8e-08 33.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 ABX11987.1 - 4.7e-08 32.8 0.1 5.6e-08 32.6 0.1 1.3 1 1 0 1 1 1 1 recA bacterial DNA recombination protein Zot PF05707.12 ABX11987.1 - 6e-06 26.0 0.1 8.4e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) ATPase_2 PF01637.18 ABX11987.1 - 1e-05 25.6 0.6 1.6e-05 24.9 0.6 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 ABX11987.1 - 0.00031 20.4 0.0 0.0016 18.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ABX11987.1 - 0.00033 21.2 1.6 0.00038 21.0 1.1 1.3 1 1 0 1 1 1 1 ABC transporter DnaB_C PF03796.15 ABX11987.1 - 0.00065 19.1 0.9 0.0089 15.4 0.1 2.2 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 ABX11987.1 - 0.0039 17.0 0.1 0.013 15.2 0.1 1.8 1 1 1 2 2 2 1 IstB-like ATP binding protein CbiA PF01656.23 ABX11987.1 - 0.0094 16.0 0.7 0.019 15.0 0.7 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 ABX11987.1 - 0.013 15.9 0.8 0.025 15.0 0.8 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 ABX11987.1 - 0.016 14.2 0.1 0.027 13.4 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.16 ABX11987.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 ABX11987.1 - 0.081 13.2 0.2 0.14 12.5 0.2 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 ABX11987.1 - 0.11 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 ABX11987.1 - 0.18 11.4 0.8 0.51 9.9 0.8 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DEAD PF00270.29 ABX11988.1 - 1.2e-35 122.9 0.2 4.3e-35 121.0 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_assoc PF08494.11 ABX11988.1 - 4.7e-27 95.0 0.0 1.1e-26 93.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/H associated Helicase_C PF00271.31 ABX11988.1 - 2e-21 76.4 1.7 2.5e-18 66.4 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 ABX11988.1 - 6e-12 45.9 0.0 1.7e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ABX11988.1 - 2.7e-05 23.1 0.1 4.7e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HypA PF01155.19 ABX11988.1 - 0.0085 16.1 0.1 0.044 13.8 0.0 2.2 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA AAA_19 PF13245.6 ABX11988.1 - 0.011 16.1 0.2 0.085 13.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 ABX11988.1 - 0.1 12.1 0.6 1.3 8.5 0.0 2.7 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 ABX11988.1 - 0.27 11.5 1.7 3.4 7.9 0.4 3.1 2 1 0 2 2 2 0 AAA domain Secretin_N_2 PF07655.13 ABX11988.1 - 2.3 8.8 5.1 4.8 7.8 5.1 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain tRNA_anti-codon PF01336.25 ABX11989.1 - 3.1e-10 39.9 0.1 0.0067 16.4 0.0 3.6 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 ABX11989.1 - 2.8e-07 30.5 0.0 7.8e-06 25.8 0.0 2.5 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 REPA_OB_2 PF16900.5 ABX11989.1 - 4.7e-07 29.7 0.5 0.033 14.1 0.0 3.4 3 0 0 3 3 3 3 Replication protein A OB domain POT1PC PF16686.5 ABX11989.1 - 0.00051 19.9 0.0 3.6 7.4 0.0 3.2 3 0 0 3 3 3 2 ssDNA-binding domain of telomere protection protein ABC_tran PF00005.27 ABX11990.1 - 1.2e-28 100.3 0.0 2e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABX11990.1 - 1.5e-13 51.2 0.1 4e-07 30.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ABX11990.1 - 1.6e-06 28.1 0.0 0.00022 21.1 0.0 3.0 1 1 0 1 1 1 1 AAA ATPase domain DUF4162 PF13732.6 ABX11990.1 - 2.9e-05 24.7 1.4 0.0001 22.9 1.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_29 PF13555.6 ABX11990.1 - 0.0071 16.1 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 ABX11990.1 - 0.027 13.9 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 ABX11990.1 - 0.078 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 ABX11990.1 - 0.11 11.9 0.4 14 5.1 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABX11990.1 - 0.13 12.7 7.0 0.57 10.7 7.0 2.3 1 1 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 ABX11991.1 - 4e-22 78.7 20.4 6.5e-22 78.0 20.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 ABX11991.1 - 3.6e-14 52.6 33.4 3.8e-14 52.6 22.9 2.0 1 1 1 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 ABX11991.1 - 0.0066 16.4 9.2 0.0066 16.4 9.2 1.9 2 1 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 ABX11991.1 - 0.014 14.7 16.2 0.02 14.2 16.2 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3493 PF11998.8 ABX11991.1 - 0.09 13.0 1.6 0.51 10.5 0.0 2.7 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 UDPG_MGDP_dh_N PF03721.14 ABX11992.1 - 3.2e-05 23.6 0.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 ABX11992.1 - 0.00088 19.5 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh PF00984.19 ABX11992.1 - 0.0016 18.6 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 ABX11992.1 - 0.076 13.2 0.0 0.39 10.9 0.0 2.0 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF354 PF04007.12 ABX11993.1 - 4.2e-44 151.0 4.8 5.1e-44 150.7 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF354) LpxB PF02684.15 ABX11993.1 - 8.8e-05 21.5 0.4 0.00019 20.4 0.4 1.6 1 1 0 1 1 1 1 Lipid-A-disaccharide synthetase Glyco_tran_28_C PF04101.16 ABX11993.1 - 0.0055 16.7 3.3 0.098 12.6 3.3 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Epimerase_2 PF02350.19 ABX11993.1 - 0.0097 14.8 0.5 0.017 14.0 0.5 1.4 2 0 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase Glycos_transf_1 PF00534.20 ABX11993.1 - 0.017 14.7 2.2 0.027 14.0 1.1 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 Shikimate_DH PF01488.20 ABX11993.1 - 0.048 13.7 0.0 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3015 PF11220.8 ABX11993.1 - 0.06 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DUF3783 PF12646.7 ABX11994.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) GrpE PF01025.19 ABX11995.1 - 6.5e-37 126.7 5.1 7.8e-37 126.5 5.1 1.1 1 0 0 1 1 1 1 GrpE GHL13 PF14883.6 ABX11995.1 - 0.03 13.4 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 DUF948 PF06103.11 ABX11995.1 - 0.036 14.3 1.3 1.7 8.9 0.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NdhM PF10664.9 ABX11995.1 - 0.044 14.0 1.0 0.099 12.9 0.5 1.9 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M KinB_sensor PF16767.5 ABX11995.1 - 0.11 13.0 1.8 0.25 11.8 1.3 1.8 1 1 1 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Spectrin PF00435.21 ABX11995.1 - 0.12 12.9 3.8 0.18 12.3 2.8 1.8 2 0 0 2 2 2 0 Spectrin repeat DUF3837 PF12939.7 ABX11995.1 - 0.18 12.2 2.8 0.91 10.0 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) UPF0184 PF03670.13 ABX11995.1 - 0.59 10.6 8.4 0.099 13.0 4.0 2.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) HSP70 PF00012.20 ABX11996.1 - 1.5e-215 716.9 19.9 4.5e-213 708.8 19.9 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ABX11996.1 - 8.8e-20 70.8 7.0 8.8e-20 70.8 7.0 2.4 2 1 0 2 2 2 1 MreB/Mbl protein Collagen PF01391.18 ABX11996.1 - 3.4e-06 26.7 15.6 6e-06 25.9 15.6 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) FGGY_C PF02782.16 ABX11996.1 - 0.0001 22.1 0.1 0.00021 21.1 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Myc-LZ PF02344.15 ABX11996.1 - 0.052 13.6 0.5 0.13 12.4 0.5 1.6 1 0 0 1 1 1 0 Myc leucine zipper domain RAP1 PF07218.11 ABX11996.1 - 0.12 10.7 7.0 0.2 9.9 7.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FtsA PF14450.6 ABX11996.1 - 0.23 11.9 6.6 4.8 7.7 0.5 3.8 3 1 0 3 3 3 0 Cell division protein FtsA Lipoprotein_10 PF03202.13 ABX11996.1 - 0.25 11.8 3.7 0.49 10.8 3.7 1.5 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region DnaJ_C PF01556.18 ABX11997.1 - 3.3e-39 134.3 0.2 4.2e-39 134.0 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ABX11997.1 - 5.5e-27 93.7 1.5 8.5e-27 93.1 1.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ABX11997.1 - 3.9e-13 49.5 21.0 7.3e-13 48.7 21.0 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ABX11997.1 - 0.081 12.9 19.9 0.44 10.5 6.5 3.2 1 1 3 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein NT5C PF06941.12 ABX11998.1 - 1.3e-12 48.0 1.8 1.5e-12 47.8 1.8 1.1 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 5-nucleotidase PF06189.12 ABX11998.1 - 0.093 11.7 0.0 0.79 8.6 0.0 1.9 2 0 0 2 2 2 0 5'-nucleotidase GatB_N PF02934.15 ABX11999.1 - 1.2e-62 211.8 0.1 1.2e-62 211.8 0.1 1.6 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 ABX11999.1 - 6.5e-20 71.5 9.4 6.5e-20 71.5 9.4 2.3 3 0 0 3 3 3 1 GatB domain YqeY PF09424.10 ABX11999.1 - 0.0029 17.7 0.4 0.009 16.1 0.4 1.8 1 0 0 1 1 1 1 Yqey-like protein Asparaginase PF00710.20 ABX12000.1 - 1.1e-55 188.1 0.3 2.1e-55 187.2 0.3 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 ABX12000.1 - 1.2e-31 109.2 0.0 2.5e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain GatD_N PF18195.1 ABX12000.1 - 1.1e-18 66.3 2.5 3.7e-18 64.6 2.0 2.2 2 0 0 2 2 2 1 GatD N-terminal domain AAA PF00004.29 ABX12001.1 - 2.6e-99 328.8 0.0 3e-49 166.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 ABX12001.1 - 9.3e-30 102.7 0.2 3e-29 101.0 0.2 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_lid_3 PF17862.1 ABX12001.1 - 9.7e-23 79.7 0.2 1.1e-11 44.3 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 ABX12001.1 - 6.6e-16 58.9 0.0 4.3e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ABX12001.1 - 7.1e-16 59.1 0.1 2.9e-06 27.8 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 ABX12001.1 - 1.4e-14 54.2 0.0 7.5e-09 35.5 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ABX12001.1 - 1.1e-10 41.9 0.4 0.0025 18.1 0.0 3.9 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 ABX12001.1 - 1.4e-10 40.9 0.1 0.00014 21.2 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 ABX12001.1 - 6.1e-10 39.4 0.0 0.0014 18.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ABX12001.1 - 1.4e-09 38.1 0.6 0.0011 18.9 0.1 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ABX12001.1 - 8.5e-09 35.5 0.0 0.0012 18.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 ABX12001.1 - 1e-08 34.8 0.1 2.2e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 ABX12001.1 - 7.7e-08 32.3 0.0 0.0076 16.0 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 ABX12001.1 - 2.2e-07 30.7 0.1 0.039 13.7 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 ABX12001.1 - 1.6e-06 28.5 0.0 0.044 14.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Bac_DnaA PF00308.18 ABX12001.1 - 2.2e-06 27.7 0.0 0.0031 17.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein TsaE PF02367.17 ABX12001.1 - 2.6e-06 27.5 0.0 0.055 13.5 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 ABX12001.1 - 2.8e-06 27.0 0.0 0.035 13.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 ABX12001.1 - 3.3e-06 27.5 0.0 0.026 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 ABX12001.1 - 3.4e-06 26.6 1.1 0.12 11.7 0.0 3.7 3 1 1 4 4 3 2 KaiC AAA_18 PF13238.6 ABX12001.1 - 4e-06 27.4 0.0 0.029 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ABX12001.1 - 8.2e-06 25.3 0.9 0.039 13.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ABX12001.1 - 9e-06 25.5 0.0 0.034 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 ABX12001.1 - 2.5e-05 23.8 0.2 0.23 10.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ATPase_2 PF01637.18 ABX12001.1 - 5e-05 23.3 0.0 0.063 13.2 0.0 3.5 2 2 0 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 ABX12001.1 - 6.9e-05 22.8 0.1 0.67 9.9 0.0 3.3 4 0 0 4 4 4 2 NACHT domain ABC_tran PF00005.27 ABX12001.1 - 7.2e-05 23.3 0.0 0.76 10.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter NB-ARC PF00931.22 ABX12001.1 - 0.00013 21.3 0.0 0.43 9.7 0.0 2.7 3 0 0 3 3 2 2 NB-ARC domain Zeta_toxin PF06414.12 ABX12001.1 - 0.00014 21.2 0.1 0.15 11.3 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 ABX12001.1 - 0.00018 20.7 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 ABX12001.1 - 0.00045 20.0 0.2 1.2 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 ABX12001.1 - 0.00061 19.7 0.0 0.51 10.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 ABX12001.1 - 0.00064 19.5 0.1 0.68 9.6 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase DUF2075 PF09848.9 ABX12001.1 - 0.00091 18.6 0.0 0.39 9.9 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 ABX12001.1 - 0.0011 18.9 1.9 10 6.0 0.0 4.4 3 1 1 4 4 4 0 NTPase AAA_25 PF13481.6 ABX12001.1 - 0.0014 18.3 6.1 1.3 8.5 0.2 3.7 2 2 1 3 3 3 1 AAA domain Parvo_NS1 PF01057.17 ABX12001.1 - 0.0016 17.6 0.1 0.31 10.1 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 ABX12001.1 - 0.002 17.9 0.2 0.68 9.7 0.0 2.6 3 0 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.6 ABX12001.1 - 0.0044 17.1 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 ABX12001.1 - 0.0079 15.6 0.0 3.3 7.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein Vps4_C PF09336.10 ABX12001.1 - 0.0092 16.0 0.9 2.3 8.3 0.2 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain CPT PF07931.12 ABX12001.1 - 0.0094 15.8 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 ABX12001.1 - 0.015 15.0 0.2 3.4 7.5 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 ABX12001.1 - 0.015 14.9 0.0 6.4 6.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Guanylate_kin PF00625.21 ABX12001.1 - 0.016 14.9 0.1 12 5.6 0.0 3.6 3 1 1 4 4 3 0 Guanylate kinase AAA_17 PF13207.6 ABX12001.1 - 0.02 15.3 0.0 1.2 9.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ABX12001.1 - 0.025 13.6 0.0 6.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 ABX12001.1 - 0.026 14.5 0.0 6.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ABX12001.1 - 0.027 14.8 2.8 3.9 7.8 0.1 3.6 3 1 1 4 4 3 0 AAA domain AFG1_ATPase PF03969.16 ABX12001.1 - 0.043 12.7 0.0 8.1 5.2 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Viral_helicase1 PF01443.18 ABX12001.1 - 0.05 13.3 0.0 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 ABX12001.1 - 0.053 13.3 0.0 19 5.0 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PIF1 PF05970.14 ABX12001.1 - 0.088 12.0 0.0 9.5 5.3 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase IPT PF01745.16 ABX12001.1 - 0.18 11.2 0.2 12 5.1 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Torsin PF06309.11 ABX12001.1 - 0.21 11.7 0.1 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Torsin Ribosomal_L2_C PF03947.18 ABX12002.1 - 1e-35 122.6 2.1 3.6e-35 120.9 2.4 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ABX12002.1 - 9.2e-09 35.2 0.0 2.4e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Acylphosphatase PF00708.18 ABX12003.1 - 1.8e-24 86.0 0.5 1.9e-24 85.8 0.5 1.0 1 0 0 1 1 1 1 Acylphosphatase YbjQ_1 PF01906.17 ABX12003.1 - 0.085 13.5 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative heavy-metal-binding ATP_bind_3 PF01171.20 ABX12005.1 - 3e-20 72.7 0.0 4.8e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 ABX12005.1 - 3e-05 23.0 0.0 5.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.19 ABX12005.1 - 0.00046 20.3 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueH PF02677.14 ABX12005.1 - 0.046 13.8 6.8 0.56 10.3 0.0 2.7 2 1 0 3 3 3 0 Epoxyqueuosine reductase QueH zf-RING_6 PF14835.6 ABX12005.1 - 0.066 13.1 0.5 0.066 13.1 0.5 2.4 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Asn_synthase PF00733.21 ABX12005.1 - 0.19 11.4 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase C1_1 PF00130.22 ABX12005.1 - 4.9 7.1 16.3 0.17 11.8 3.4 3.4 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Methyltransf_23 PF13489.6 ABX12006.1 - 9.3e-18 64.6 0.0 1.5e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABX12006.1 - 2.4e-12 47.3 0.0 4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABX12006.1 - 1.1e-09 38.9 0.0 2.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABX12006.1 - 2.2e-08 34.0 0.1 3.7e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX12006.1 - 2e-07 31.6 0.0 5.1e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 ABX12006.1 - 4.6e-05 23.1 0.0 0.00019 21.1 0.0 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW DREV PF05219.12 ABX12006.1 - 0.0025 17.0 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Peptidase_M50 PF02163.22 ABX12007.1 - 1.4e-19 70.4 0.0 2.7e-08 33.4 1.4 2.4 1 1 1 2 2 2 2 Peptidase family M50 PDZ_2 PF13180.6 ABX12007.1 - 3.7e-09 36.8 0.0 7.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 ABX12007.1 - 1.2e-06 28.3 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ABX12007.1 - 0.0089 16.4 0.1 0.022 15.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain CutA1 PF03091.15 ABX12008.1 - 9.2e-30 102.4 2.6 1e-29 102.3 2.6 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein eRF1_1 PF03463.15 ABX12009.1 - 6.3e-19 68.2 1.0 6.3e-19 68.2 1.0 1.7 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.15 ABX12009.1 - 3.1e-08 34.1 2.0 1.3e-07 32.1 0.2 2.8 3 1 0 3 3 3 1 eRF1 domain 3 eRF1_2 PF03464.15 ABX12009.1 - 0.0006 20.1 0.4 0.0015 18.8 0.2 1.8 1 1 0 1 1 1 1 eRF1 domain 2 baeRF_family7 PF18849.1 ABX12009.1 - 0.0023 18.1 0.2 0.03 14.5 0.0 2.2 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 7 DUF5507 PF17612.2 ABX12009.1 - 0.0034 17.1 0.3 0.0066 16.2 0.3 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5507) RNB PF00773.19 ABX12009.1 - 0.025 13.9 0.2 0.036 13.4 0.2 1.2 1 0 0 1 1 1 0 RNB domain ATPase_2 PF01637.18 ABX12009.1 - 0.028 14.3 1.0 0.06 13.2 0.6 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea UPF0047 PF01894.17 ABX12011.1 - 7.2e-36 122.8 0.0 8.8e-36 122.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fe_dep_repr_C PF02742.15 ABX12013.1 - 1e-18 67.1 0.1 2e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.19 ABX12013.1 - 2.3e-14 53.3 0.3 4.2e-14 52.5 0.3 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 ABX12013.1 - 2.1e-05 24.4 0.1 3.3e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABX12013.1 - 2.8e-05 24.5 0.0 5.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 ABX12013.1 - 9.2e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 ABX12013.1 - 0.00019 21.4 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ABX12013.1 - 0.00019 21.7 0.2 0.00038 20.8 0.1 1.5 2 0 0 2 2 1 1 Transcriptional regulator TrmB PF01978.19 ABX12013.1 - 0.00085 19.2 0.2 0.0013 18.5 0.2 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.6 ABX12013.1 - 0.0012 18.8 0.1 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_1 PF00126.27 ABX12013.1 - 0.0013 18.6 0.0 0.003 17.5 0.0 1.7 1 1 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 ABX12013.1 - 0.0018 18.1 0.0 0.0049 16.7 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 ABX12013.1 - 0.011 15.6 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 HTH domain HemN_C PF06969.16 ABX12013.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 HemN C-terminal domain HTH_6 PF01418.17 ABX12013.1 - 0.045 13.7 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_29 PF13551.6 ABX12013.1 - 0.047 13.7 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 Winged helix-turn helix NLPC_P60 PF00877.19 ABX12013.1 - 0.07 13.2 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 NlpC/P60 family HTH_IclR PF09339.10 ABX12013.1 - 0.074 12.9 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_37 PF13744.6 ABX12013.1 - 0.088 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_terminase PF10668.9 ABX12013.1 - 0.18 11.8 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Phage terminase small subunit IF2_N PF04760.15 ABX12013.1 - 0.36 10.7 2.4 0.44 10.4 0.1 2.4 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region TrmB PF01978.19 ABX12014.1 - 2.8e-22 78.4 0.1 7.6e-22 77.0 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 ABX12014.1 - 1.7e-07 30.7 0.0 2.1e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_IclR PF09339.10 ABX12014.1 - 2.3e-06 27.3 0.0 4.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 ABX12014.1 - 0.00087 18.8 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Penicillinase_R PF03965.16 ABX12014.1 - 0.0066 16.8 0.1 0.03 14.7 0.0 2.0 2 0 0 2 2 2 1 Penicillinase repressor MarR_2 PF12802.7 ABX12014.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 MarR family MarR PF01047.22 ABX12014.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.6 ABX12014.1 - 0.039 14.4 0.0 0.14 12.7 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_29 PF13551.6 ABX12014.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Rrf2 PF02082.20 ABX12014.1 - 0.063 13.6 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator PheRS_DBD3 PF18553.1 ABX12014.1 - 0.064 13.6 0.1 0.33 11.3 0.1 2.3 1 1 0 1 1 1 0 PheRS DNA binding domain 3 HTH_9 PF08221.11 ABX12014.1 - 0.068 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_34 PF13601.6 ABX12014.1 - 0.076 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain PadR PF03551.14 ABX12014.1 - 0.096 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family MerR_2 PF13591.6 ABX12014.1 - 0.15 11.9 0.0 0.82 9.6 0.0 2.1 2 0 0 2 2 2 0 MerR HTH family regulatory protein Radical_SAM PF04055.21 ABX12015.1 - 8.7e-15 55.5 0.2 8.7e-15 55.5 0.2 2.6 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.6 ABX12015.1 - 4.7e-06 26.9 0.0 1.3e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ABX12015.1 - 7.8e-06 26.0 0.0 7.8e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Glycos_transf_1 PF00534.20 ABX12016.1 - 4.8e-35 120.6 0.3 7.4e-35 120.0 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ABX12016.1 - 2.1e-24 86.5 0.0 3.4e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ABX12016.1 - 1.7e-13 50.9 0.1 8e-13 48.7 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ABX12016.1 - 6e-10 39.4 0.0 1.7e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ABX12016.1 - 1e-08 35.8 0.0 0.00017 22.1 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 ABX12016.1 - 0.00034 20.4 0.1 0.00083 19.1 0.1 1.8 2 1 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_2 PF13477.6 ABX12016.1 - 0.00053 20.0 0.4 0.0055 16.7 0.4 2.4 1 1 0 1 1 1 1 Glycosyl transferase 4-like CCT PF06203.14 ABX12016.1 - 0.1 12.6 0.3 0.19 11.8 0.3 1.4 1 0 0 1 1 1 0 CCT motif Polysacc_synt_2 PF02719.15 ABX12017.1 - 7.6e-95 317.4 1.8 8.9e-95 317.2 1.8 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ABX12017.1 - 6.4e-24 84.7 0.3 1.2e-22 80.6 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABX12017.1 - 8.6e-20 70.9 1.1 1.4e-19 70.1 1.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ABX12017.1 - 3e-17 62.6 0.2 9.4e-16 57.7 0.2 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ABX12017.1 - 7.5e-17 61.7 0.4 2.2e-16 60.2 0.4 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ABX12017.1 - 4.1e-13 49.6 0.0 5.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 ABX12017.1 - 1.3e-07 31.3 1.6 2.3e-07 30.5 1.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 ABX12017.1 - 3.4e-06 26.4 4.4 0.00012 21.4 2.6 2.9 1 1 1 2 2 2 1 Male sterility protein KR PF08659.10 ABX12017.1 - 7.3e-06 26.0 0.0 1.3e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 ABX12017.1 - 8.6e-06 25.5 0.9 1.2e-05 25.0 0.9 1.2 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 ABX12017.1 - 0.00045 20.8 0.8 0.0049 17.4 0.0 2.8 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ABX12017.1 - 0.0062 16.6 0.4 0.021 14.9 0.1 2.0 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 ABX12017.1 - 0.012 16.0 0.3 0.5 10.8 0.0 2.6 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF917 PF06032.12 ABX12017.1 - 0.03 13.2 0.1 3.6 6.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF917) DapB_N PF01113.20 ABX12017.1 - 0.03 14.4 0.2 0.072 13.2 0.1 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PMT_2 PF13231.6 ABX12018.1 - 4.1e-07 30.3 29.8 8.4e-07 29.3 13.9 2.6 2 1 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase STT3 PF02516.14 ABX12018.1 - 0.001 18.1 17.2 0.001 18.1 17.2 2.3 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Polysacc_synt PF01943.17 ABX12019.1 - 2.7e-06 27.0 43.1 4.8e-06 26.2 30.3 3.2 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 ABX12019.1 - 0.0028 17.7 10.5 0.0028 17.7 10.5 4.2 1 1 3 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Polysacc_synt_3 PF13440.6 ABX12019.1 - 0.0049 16.1 1.1 0.0049 16.1 1.1 3.2 2 1 0 3 3 3 2 Polysaccharide biosynthesis protein Glycos_transf_1 PF00534.20 ABX12020.1 - 5.9e-38 130.1 0.1 9.8e-38 129.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ABX12020.1 - 2.8e-22 79.6 0.0 5e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ABX12020.1 - 5.6e-12 46.0 0.0 8.1e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ABX12020.1 - 4.4e-11 43.0 0.0 1.2e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 ABX12020.1 - 0.00078 19.5 1.8 0.0017 18.4 0.4 2.3 2 1 1 3 3 3 1 Glycosyl transferase 4-like DUF2358 PF10184.9 ABX12020.1 - 0.2 11.9 4.5 0.12 12.7 0.5 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) Glyco_trans_4_4 PF13579.6 ABX12020.1 - 0.27 11.7 0.0 0.41 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Epimerase PF01370.21 ABX12021.1 - 2.9e-45 154.6 0.1 3.5e-45 154.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABX12021.1 - 2e-36 126.1 0.8 9.9e-36 123.8 0.8 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ABX12021.1 - 4.1e-27 95.0 0.0 4.7e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ABX12021.1 - 4.9e-15 55.4 4.5 3.2e-14 52.7 4.5 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ABX12021.1 - 5.4e-14 51.9 2.8 8.8e-14 51.2 2.8 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ABX12021.1 - 5.2e-09 35.6 0.1 1e-05 24.8 0.0 3.0 1 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 ABX12021.1 - 0.0001 21.8 0.2 0.0002 20.9 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 ABX12021.1 - 0.00011 22.2 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 ABX12021.1 - 0.0086 16.2 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 ABX12021.1 - 0.021 14.7 0.1 1.2 9.0 0.1 2.8 1 1 1 2 2 2 0 KR domain DUF1493 PF07377.12 ABX12021.1 - 0.096 13.2 0.2 0.3 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) GDP_Man_Dehyd PF16363.5 ABX12022.1 - 3.9e-48 164.6 0.0 5.3e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ABX12022.1 - 2.5e-42 145.0 0.0 2.9e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABX12022.1 - 3.1e-14 52.8 0.0 3.7e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ABX12022.1 - 2.6e-08 33.2 0.3 7.1e-08 31.8 0.3 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ABX12022.1 - 5.8e-05 22.4 0.0 0.045 12.9 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 ABX12022.1 - 6.7e-05 22.2 0.0 0.0002 20.6 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ABX12022.1 - 0.00053 19.9 0.0 0.00076 19.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ABX12022.1 - 0.0028 17.6 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 ABX12022.1 - 0.017 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 ABX12022.1 - 0.034 13.6 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Glycos_transf_2 PF00535.26 ABX12023.1 - 3.2e-26 92.1 0.0 5.4e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ABX12023.1 - 5.9e-20 72.1 0.0 9.1e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ABX12023.1 - 8.8e-06 25.3 0.0 2.1e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 ABX12023.1 - 2.8e-05 24.1 0.0 7.3e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 ABX12023.1 - 0.0025 18.3 0.0 0.009 16.5 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 2 NTP_transferase PF00483.23 ABX12024.1 - 1.6e-56 191.7 0.0 2.1e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ABX12024.1 - 1.1e-10 42.1 0.0 1.6e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 ABX12024.1 - 2.9e-09 36.3 15.3 4.2e-08 32.6 6.5 3.3 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ABX12024.1 - 2.6e-05 23.9 5.9 2.6e-05 23.9 5.9 2.4 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ABX12024.1 - 0.0011 17.9 1.3 0.0024 16.9 1.3 1.5 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 ABX12024.1 - 0.007 14.6 4.0 0.012 13.8 4.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 ABX12024.1 - 0.09 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase GDP_Man_Dehyd PF16363.5 ABX12025.1 - 2.7e-80 270.3 0.1 3.2e-80 270.0 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ABX12025.1 - 2.5e-56 190.9 0.0 3.1e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABX12025.1 - 6.9e-19 67.9 0.5 8.7e-19 67.6 0.5 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ABX12025.1 - 3.4e-13 49.4 0.2 2.2e-12 46.7 0.2 2.3 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ABX12025.1 - 8.2e-13 48.1 0.1 2.4e-12 46.6 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ABX12025.1 - 3.5e-12 46.0 0.0 4.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ABX12025.1 - 0.00041 20.3 0.0 0.00056 19.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 ABX12025.1 - 0.063 12.7 0.1 0.45 9.9 0.1 2.2 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 ABX12025.1 - 0.067 12.7 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family DUF5470 PF17564.2 ABX12025.1 - 0.088 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5470) KR PF08659.10 ABX12025.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 KR domain Lipase_GDSL_2 PF13472.6 ABX12026.1 - 2.6e-08 34.5 0.0 4.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ABX12026.1 - 0.0016 18.4 0.0 0.034 14.1 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TGF_beta_GS PF08515.12 ABX12026.1 - 0.42 10.2 1.3 0.88 9.1 1.3 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Carbam_trans_N PF02543.15 ABX12027.1 - 1.3e-85 288.0 0.1 1.7e-85 287.6 0.1 1.1 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus Carbam_trans_C PF16861.5 ABX12027.1 - 1.7e-72 242.6 0.0 7.3e-72 240.5 0.0 1.9 2 0 0 2 2 2 1 Carbamoyltransferase C-terminus Peptidase_M22 PF00814.25 ABX12027.1 - 4.8e-05 23.2 0.0 0.001 18.9 0.0 2.2 2 0 0 2 2 2 1 Glycoprotease family Sua5_yciO_yrdC PF01300.18 ABX12027.1 - 0.0084 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination MIT_C PF16565.5 ABX12028.1 - 0.057 13.4 0.2 0.094 12.7 0.2 1.3 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT NeuB PF03102.14 ABX12031.1 - 6.5e-87 291.0 0.0 7.8e-87 290.7 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 ABX12031.1 - 0.018 15.7 0.1 0.044 14.4 0.1 1.7 1 0 0 1 1 1 0 SAF domain DegT_DnrJ_EryC1 PF01041.17 ABX12032.1 - 1.4e-101 340.4 0.0 1.6e-101 340.2 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ABX12032.1 - 7e-08 32.0 0.2 1.1e-07 31.4 0.2 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ABX12032.1 - 1.2e-06 28.0 0.0 2.3e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 ABX12032.1 - 6.3e-05 21.8 1.0 7.5e-05 21.6 1.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Cys_Met_Meta_PP PF01053.20 ABX12032.1 - 0.00011 20.9 0.1 0.00017 20.3 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 ABX12032.1 - 0.00044 19.0 0.0 0.00077 18.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.19 ABX12032.1 - 0.0014 17.6 0.1 0.0028 16.7 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-V Acetyltransf_4 PF13420.7 ABX12033.1 - 0.055 13.6 2.7 0.15 12.2 2.7 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Formyl_trans_N PF00551.19 ABX12034.1 - 3.2e-12 46.5 0.0 3.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase CTP_transf_3 PF02348.19 ABX12035.1 - 2.5e-27 96.2 1.1 3e-27 96.0 1.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 ABX12035.1 - 0.00025 21.5 0.0 0.001 19.5 0.0 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain GFO_IDH_MocA PF01408.22 ABX12036.1 - 7.6e-18 65.5 0.0 1.4e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.21 ABX12036.1 - 4.4e-07 29.5 0.0 6.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 ABX12036.1 - 0.00036 20.6 0.1 0.00099 19.2 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 ABX12036.1 - 0.00053 19.4 0.0 0.0012 18.3 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ABX12036.1 - 0.00081 19.7 0.6 0.01 16.1 0.1 2.7 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain IlvN PF07991.12 ABX12036.1 - 0.00093 18.8 0.1 0.003 17.2 0.1 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 ABX12036.1 - 0.0012 19.1 0.0 0.0035 17.6 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 ABX12036.1 - 0.0013 19.1 0.2 0.0074 16.7 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding F420_oxidored PF03807.17 ABX12036.1 - 0.0061 17.1 0.1 0.03 14.9 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent XkdW PF09636.10 ABX12036.1 - 0.027 14.5 1.4 1.4 9.0 0.2 3.0 3 0 0 3 3 3 0 XkdW protein ApbA PF02558.16 ABX12036.1 - 0.12 12.1 0.1 0.71 9.5 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 ABX12036.1 - 0.12 12.0 1.3 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4910 PF16254.5 ABX12037.1 - 2.9e-93 311.3 0.1 3.4e-93 311.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4910) DUF2172 PF09940.9 ABX12037.1 - 1.2e-32 112.1 0.3 3.3e-32 110.7 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2172) Peptidase_M28 PF04389.17 ABX12037.1 - 1.5e-10 41.1 0.0 2.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 HTH_47 PF16221.5 ABX12037.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 winged helix-turn-helix ACPS PF01648.20 ABX12038.1 - 3.7e-21 75.4 0.1 4.2e-21 75.2 0.1 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 ABX12038.1 - 0.18 12.0 0.0 0.25 11.5 0.0 1.4 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Epimerase_2 PF02350.19 ABX12039.1 - 2.6e-08 33.1 0.1 4.5e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase SRI PF08236.11 ABX12039.1 - 0.068 13.4 9.7 0.1 12.8 3.8 3.1 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain HMGL-like PF00682.19 ABX12040.1 - 1.9e-39 135.8 0.0 3.1e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 HMGL-like DmpG_comm PF07836.11 ABX12040.1 - 3.4e-06 26.5 0.0 1e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 DmpG-like communication domain AMP-binding PF00501.28 ABX12041.1 - 1e-52 179.2 0.0 1.3e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABX12041.1 - 3.3e-07 31.2 0.0 5.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cyclase PF04199.13 ABX12042.1 - 1.8e-28 99.4 0.0 2.5e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase PP-binding PF00550.25 ABX12043.1 - 5.3e-05 23.5 0.1 8.1e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site DUF3964 PF13107.6 ABX12043.1 - 0.029 14.8 0.1 0.039 14.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3964) Antibiotic_NAT PF02522.14 ABX12044.1 - 6.7e-31 107.8 0.0 7.6e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Aminoglycoside 3-N-acetyltransferase FdtA PF05523.11 ABX12045.1 - 3.1e-32 111.0 0.1 3.5e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 WxcM-like, C-terminal Cupin_1 PF00190.22 ABX12045.1 - 0.00018 21.2 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 ABX12045.1 - 0.00068 19.3 0.0 0.0023 17.6 0.0 1.8 1 1 0 1 1 1 1 Cupin domain dTDP_sugar_isom PF00908.17 ABX12045.1 - 0.028 14.1 0.0 0.05 13.3 0.0 1.4 1 1 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase Asp4 PF16996.5 ABX12045.1 - 0.14 11.9 0.6 0.39 10.5 0.1 2.0 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 Polysacc_synt_2 PF02719.15 ABX12046.1 - 9.6e-98 326.9 0.1 1.2e-97 326.6 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ABX12046.1 - 8.4e-29 100.7 0.0 6.5e-28 97.8 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABX12046.1 - 1.8e-23 82.9 0.0 2.2e-19 69.6 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ABX12046.1 - 1.2e-18 67.6 0.0 6.5e-17 61.9 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ABX12046.1 - 1.6e-15 57.0 0.0 6.4e-14 51.7 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ABX12046.1 - 8.1e-13 48.7 0.0 1.2e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ABX12046.1 - 8.5e-11 41.5 3.5 1.4e-06 27.6 2.2 3.2 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 ABX12046.1 - 4e-10 39.7 0.8 8.5e-10 38.6 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 ABX12046.1 - 3.1e-07 30.5 0.0 5.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 ABX12046.1 - 3e-06 26.9 0.0 4.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.20 ABX12046.1 - 0.00064 19.8 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ABX12046.1 - 0.008 16.7 0.0 0.033 14.8 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GCD14_N PF14801.6 ABX12046.1 - 0.04 13.7 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term TrkA_N PF02254.18 ABX12046.1 - 0.12 12.7 0.0 0.33 11.2 0.0 1.9 2 1 0 2 2 2 0 TrkA-N domain Epimerase_2 PF02350.19 ABX12047.1 - 4e-06 25.9 0.0 1.6e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase Aminotran_3 PF00202.21 ABX12048.1 - 1.5e-39 135.8 0.0 2.6e-38 131.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III CTP_transf_3 PF02348.19 ABX12049.1 - 5.5e-12 46.1 0.7 8.4e-12 45.5 0.7 1.2 1 0 0 1 1 1 1 Cytidylyltransferase GDP_Man_Dehyd PF16363.5 ABX12050.1 - 1.3e-111 373.2 0.0 1.6e-111 373.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ABX12050.1 - 3.7e-58 196.9 0.0 4.5e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABX12050.1 - 1.6e-07 30.8 0.0 2.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 ABX12050.1 - 6.5e-05 22.6 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 ABX12050.1 - 0.0064 16.0 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase GFO_IDH_MocA PF01408.22 ABX12051.1 - 5.3e-07 30.5 0.0 1e-06 29.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.19 ABX12051.1 - 0.0053 16.1 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SapC PF07277.11 ABX12051.1 - 0.09 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SapC Sulfatase PF00884.23 ABX12052.1 - 1.4e-32 113.4 0.0 2.2e-31 109.4 0.0 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ABX12052.1 - 1.1e-11 45.0 0.1 1.5e-06 28.0 0.0 2.3 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 ABX12052.1 - 6.1e-05 22.9 0.1 0.00015 21.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 ABX12052.1 - 0.00019 21.7 0.2 0.00068 19.9 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Metalloenzyme PF01676.18 ABX12052.1 - 0.012 15.0 0.0 0.038 13.4 0.0 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily Sulfatase_C PF14707.6 ABX12052.1 - 0.029 15.1 0.2 0.059 14.1 0.2 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase HTH_3 PF01381.22 ABX12053.1 - 1.4e-11 44.2 0.1 1.2e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix Cupin_2 PF07883.11 ABX12053.1 - 4.5e-06 26.3 0.2 0.1 12.3 0.0 2.7 2 1 0 2 2 2 2 Cupin domain HTH_31 PF13560.6 ABX12053.1 - 5.9e-05 23.3 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_26 PF13443.6 ABX12053.1 - 0.00088 19.7 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 ABX12053.1 - 0.008 16.2 0.4 1.9 8.5 0.1 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain Sulfatase PF00884.23 ABX12054.1 - 1.2e-21 77.4 1.2 1.9e-20 73.5 1.2 2.0 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 ABX12054.1 - 3.4e-07 30.5 1.0 8.9e-07 29.1 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 ABX12054.1 - 8.7e-05 22.3 2.5 0.0035 17.0 2.5 2.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 ABX12054.1 - 0.00012 20.8 0.4 0.00015 20.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) NTP_transf_3 PF12804.7 ABX12055.1 - 2.4e-12 47.5 0.0 3.6e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 ABX12055.1 - 1.8e-07 31.2 0.0 3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transferase PF00483.23 ABX12055.1 - 1.6e-05 24.6 0.1 3.8e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase PEP_mutase PF13714.6 ABX12056.1 - 2.1e-67 227.1 0.3 2.5e-67 226.8 0.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 ABX12056.1 - 1.4e-05 23.8 0.1 2.5e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 ABX12056.1 - 0.0096 15.3 0.3 0.26 10.6 0.1 2.5 1 1 1 2 2 2 1 Ketopantoate hydroxymethyltransferase PucR PF07905.11 ABX12056.1 - 0.013 15.8 0.0 0.44 10.8 0.0 2.5 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family Fe-ADH PF00465.19 ABX12057.1 - 7.8e-50 169.7 0.0 2.6e-49 168.0 0.0 1.7 1 1 1 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ABX12057.1 - 1.4e-15 57.7 0.0 1.9e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 ABX12057.1 - 0.0009 18.5 0.0 0.07 12.3 0.0 2.3 2 0 0 2 2 2 2 3-dehydroquinate synthase VATC PF18716.1 ABX12057.1 - 0.87 9.5 3.0 4.3 7.3 0.3 2.5 2 0 0 2 2 2 0 Vms1-associating treble clef domain Rieske PF00355.26 ABX12058.1 - 5.2e-15 55.1 0.0 6.5e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ABX12058.1 - 2.9e-06 27.2 0.0 3.3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Lactamase_B_3 PF13483.6 ABX12059.1 - 6.4e-15 55.4 0.0 1.4e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 ABX12059.1 - 4e-05 23.2 0.0 6.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ABX12059.1 - 0.00038 20.5 0.0 0.00063 19.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CBS PF00571.28 ABX12060.1 - 3.1e-25 88.4 2.7 4.3e-05 23.9 0.0 4.2 4 0 0 4 4 4 4 CBS domain Glycos_transf_2 PF00535.26 ABX12061.1 - 3.7e-26 91.9 0.1 5e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ABX12061.1 - 0.00013 21.9 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ABX12061.1 - 0.0019 18.7 0.0 0.0033 17.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 ABX12061.1 - 0.0028 17.2 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RseC_MucC PF04246.12 ABX12061.1 - 0.11 12.4 0.6 0.2 11.6 0.6 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC NTP_transf_3 PF12804.7 ABX12061.1 - 0.18 12.1 0.0 0.29 11.5 0.0 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain Sulfotransfer_1 PF00685.27 ABX12062.1 - 1.9e-17 63.6 1.0 2.5e-17 63.2 1.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ABX12062.1 - 2.5e-14 54.2 0.0 1.8e-05 25.2 0.0 3.1 3 0 0 3 3 3 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 ABX12062.1 - 0.015 15.2 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 Sulfotransferase family SRPRB PF09439.10 ABX12062.1 - 0.048 13.1 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit bact-PGI_C PF10432.9 ABX12063.1 - 5.9e-38 130.3 0.1 1e-37 129.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal SIS domain SIS PF01380.22 ABX12063.1 - 2.7e-08 33.7 0.7 4.7e-08 33.0 0.0 1.8 3 0 0 3 3 3 1 SIS domain Joubert PF15392.6 ABX12063.1 - 0.027 14.2 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated SIS_2 PF13580.6 ABX12063.1 - 0.034 14.2 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 SIS domain Epimerase PF01370.21 ABX12064.1 - 1.1e-58 198.5 0.0 1.3e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABX12064.1 - 3.9e-52 177.7 0.0 1.1e-51 176.3 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ABX12064.1 - 7.4e-24 84.4 0.1 4.5e-23 81.8 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ABX12064.1 - 8.2e-24 84.1 0.1 1.3e-23 83.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ABX12064.1 - 7.3e-18 64.7 0.0 9.5e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ABX12064.1 - 1e-10 41.2 0.5 1.9e-08 33.8 0.4 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ABX12064.1 - 2e-09 37.6 0.0 5e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 ABX12064.1 - 6.1e-08 32.5 0.0 1.2e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 ABX12064.1 - 2.6e-05 24.2 0.1 0.00012 22.0 0.1 1.9 1 1 0 1 1 1 1 KR domain DapB_N PF01113.20 ABX12064.1 - 0.0034 17.5 0.0 0.0097 16.0 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 ABX12064.1 - 0.0098 15.4 0.1 0.077 12.4 0.1 2.4 1 1 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 ABX12064.1 - 0.037 14.3 0.1 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ABX12064.1 - 0.048 13.9 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Beta-lactamase2 PF13354.6 ABX12064.1 - 0.081 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family IF-2B PF01008.17 ABX12065.1 - 7.6e-85 284.5 1.7 9.3e-85 284.2 1.7 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Serine_rich PF08824.10 ABX12065.1 - 0.0025 17.9 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 Serine rich protein interaction domain PEP-utilizers PF00391.23 ABX12065.1 - 0.048 13.4 0.0 0.95 9.2 0.0 2.7 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain RRM_1 PF00076.22 ABX12065.1 - 0.08 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GFO_IDH_MocA PF01408.22 ABX12066.1 - 2.7e-06 28.2 0.0 5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 ABX12066.1 - 4.5e-05 23.8 0.1 0.0002 21.8 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding ThiF PF00899.21 ABX12066.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 ABX12066.1 - 0.0013 19.0 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 ABX12066.1 - 0.0066 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Methyltransf_25 PF13649.6 ABX12066.1 - 0.0069 17.1 0.0 0.032 14.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABX12066.1 - 0.013 16.2 0.1 0.042 14.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.18 ABX12066.1 - 0.095 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 ABX12066.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 ABX12067.1 - 3.2e-09 37.7 0.0 5.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_79n PF03662.14 ABX12067.1 - 0.037 13.0 0.1 0.065 12.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain Cas_Cas1 PF01867.16 ABX12067.1 - 0.061 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 CRISPR associated protein Cas1 GFO_IDH_MocA_C PF02894.17 ABX12067.1 - 0.14 12.2 0.0 0.51 10.4 0.0 1.9 1 1 1 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain FeS_assembly_P PF01883.19 ABX12068.1 - 1.7e-18 66.5 0.0 3.5e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein PqqD PF05402.12 ABX12068.1 - 3.8e-10 39.9 0.1 6.2e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) HemN_C PF06969.16 ABX12068.1 - 0.027 14.5 0.3 0.053 13.6 0.3 1.4 1 0 0 1 1 1 0 HemN C-terminal domain adh_short_C2 PF13561.6 ABX12069.1 - 1.8e-19 70.3 0.0 2.8e-18 66.3 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABX12069.1 - 7.8e-19 67.9 0.0 1.2e-13 51.0 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 ABX12069.1 - 0.0015 18.0 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABX12069.1 - 0.0092 15.1 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DUF2231 PF09990.9 ABX12071.1 - 0.0081 16.6 5.4 1.1 9.8 1.0 2.3 1 1 1 2 2 2 2 Predicted membrane protein (DUF2231) DUF2157 PF09925.9 ABX12071.1 - 0.6 9.9 5.1 3.8 7.3 0.0 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) PIRT PF15099.6 ABX12072.1 - 0.00026 20.5 0.8 0.00066 19.3 0.1 1.8 2 0 0 2 2 2 1 Phosphoinositide-interacting protein family Saf_2TM PF18303.1 ABX12072.1 - 0.01 15.4 0.2 4.2 6.9 0.1 2.2 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Aminotran_1_2 PF00155.21 ABX12073.1 - 1.5e-59 202.0 0.0 1.8e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ABX12073.1 - 8.6e-08 31.9 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ABX12073.1 - 7.6e-07 28.4 0.0 1.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ABX12073.1 - 0.0024 16.4 0.0 0.0034 16.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 ABX12073.1 - 0.01 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 ABX12073.1 - 0.04 13.2 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Putative_PNPOx PF01243.20 ABX12074.1 - 1.3e-15 57.3 0.0 2.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 ABX12074.1 - 4.9e-11 42.8 0.0 5.9e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 ABX12074.1 - 0.055 13.0 0.1 0.061 12.9 0.1 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like DUF308 PF03729.13 ABX12075.1 - 0.0025 18.1 0.6 1.3 9.4 0.1 2.1 2 0 0 2 2 2 2 Short repeat of unknown function (DUF308) Gram_pos_anchor PF00746.21 ABX12075.1 - 0.0047 16.8 0.1 2.3 8.2 0.0 2.2 2 0 0 2 2 2 2 LPXTG cell wall anchor motif DUF2339 PF10101.9 ABX12075.1 - 0.047 12.3 0.1 0.052 12.1 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) YfzA PF14118.6 ABX12075.1 - 0.11 12.9 0.6 0.13 12.6 0.6 1.3 1 1 0 1 1 1 0 YfzA-like protein F420_oxidored PF03807.17 ABX12076.1 - 3e-15 56.6 0.0 6.4e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ABX12076.1 - 0.023 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 ABX12076.1 - 0.05 13.9 0.1 0.099 12.9 0.1 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 ABX12076.1 - 0.053 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus His_Phos_1 PF00300.22 ABX12077.1 - 1.6e-49 168.3 0.0 1.8e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lipase_GDSL_3 PF14606.6 ABX12077.1 - 0.041 14.0 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family COX2_TM PF02790.15 ABX12078.1 - 0.043 13.9 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF2391 PF09622.10 ABX12078.1 - 0.046 13.0 0.0 0.055 12.8 0.0 1.0 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) stn_TNFRSF12A PF12191.8 ABX12078.1 - 0.2 11.9 0.7 0.21 11.8 0.3 1.4 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain COX2 PF00116.20 ABX12079.1 - 2.8e-14 53.1 1.2 2.5e-10 40.3 0.0 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.6 ABX12079.1 - 2.7e-06 27.5 0.0 3.1e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Cupredoxin-like domain COX1 PF00115.20 ABX12080.1 - 2.3e-129 432.0 62.1 2.9e-129 431.7 62.1 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Copper-bind PF00127.20 ABX12081.1 - 6.1e-13 49.1 0.1 5.2e-06 26.8 0.0 2.7 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX12081.1 - 2.1e-06 27.8 0.0 4.7e-05 23.4 0.0 2.7 3 1 0 3 3 3 1 Cupredoxin-like domain Cu-oxidase_3 PF07732.15 ABX12081.1 - 0.00023 21.2 0.1 0.00075 19.5 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase SoxE PF06525.11 ABX12081.1 - 0.1 12.1 0.2 0.32 10.5 0.1 1.8 1 1 1 2 2 2 0 Sulfocyanin (SoxE) domain Cu-oxidase_2 PF07731.14 ABX12081.1 - 0.12 12.1 0.0 1.8 8.3 0.0 2.7 4 0 0 4 4 4 0 Multicopper oxidase COX15-CtaA PF02628.15 ABX12082.1 - 7.3e-18 64.7 13.5 1.2e-14 54.2 7.7 2.0 1 1 1 2 2 2 2 Cytochrome oxidase assembly protein DUF1453 PF07301.11 ABX12082.1 - 0.033 14.2 4.2 0.047 13.7 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) PseudoU_synth_2 PF00849.22 ABX12082.1 - 0.093 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA pseudouridylate synthase Polyketide_cyc2 PF10604.9 ABX12084.1 - 4.4e-08 33.5 0.0 5.4e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ABX12084.1 - 1.2e-07 32.0 0.0 1.8e-07 31.5 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 ABX12084.1 - 2.4e-07 31.0 0.1 3.8e-07 30.4 0.1 1.4 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein HATPase_c PF02518.26 ABX12085.1 - 4.6e-21 75.4 0.1 8.2e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABX12085.1 - 3.2e-10 39.9 0.8 8.8e-10 38.5 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 ABX12085.1 - 2.6e-06 27.3 0.0 5.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 ABX12085.1 - 0.007 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABX12085.1 - 0.026 14.5 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain CobD_Cbib PF03186.13 ABX12085.1 - 0.15 11.2 0.1 0.48 9.6 0.1 1.8 1 0 0 1 1 1 0 CobD/Cbib protein DUF5381 PF17353.2 ABX12085.1 - 8.3 6.1 14.7 1.1 9.0 5.3 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5381) Methyltransf_25 PF13649.6 ABX12086.1 - 2.2e-17 63.5 0.0 3.9e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABX12086.1 - 1.6e-15 57.5 0.0 2.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABX12086.1 - 6.8e-12 45.4 0.0 9.1e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABX12086.1 - 9.7e-08 32.7 0.0 1.8e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABX12086.1 - 3.2e-07 29.9 0.0 4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ABX12086.1 - 2.6e-06 27.4 0.0 2.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ABX12086.1 - 0.089 12.4 0.0 0.15 11.6 0.0 1.3 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 ABX12086.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ribosomal_L18_c PF14204.6 ABX12086.1 - 0.77 10.7 4.9 22 6.0 0.2 2.7 3 1 0 3 3 3 0 Ribosomal L18 C-terminal region Aminotran_4 PF01063.19 ABX12088.1 - 2e-48 165.2 0.0 2.5e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV AA_kinase PF00696.28 ABX12089.1 - 2.2e-29 102.8 0.8 3.9e-29 101.9 0.5 1.6 2 0 0 2 2 2 1 Amino acid kinase family YajC PF02699.15 ABX12089.1 - 0.026 14.4 0.6 0.082 12.8 0.1 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit PASTA PF03793.19 ABX12089.1 - 0.047 13.5 0.1 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 PASTA domain Glyco_tran_28_C PF04101.16 ABX12090.1 - 8.1e-15 55.2 0.3 2.7e-14 53.5 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 ABX12090.1 - 1.9e-05 25.1 0.0 5.8e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_3 PF13528.6 ABX12090.1 - 3.4e-05 23.3 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 CCDC117 PF15810.5 ABX12090.1 - 0.025 14.9 0.2 0.053 13.8 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 LepB_N PF18640.1 ABX12090.1 - 0.038 13.6 1.0 0.077 12.6 0.4 1.7 1 1 0 1 1 1 0 LepB N-terminal domain potato_inhibit PF00280.18 ABX12092.1 - 0.058 14.1 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Potato inhibitor I family Ammonium_transp PF00909.21 ABX12094.1 - 0.0032 16.2 7.7 0.0032 16.2 7.7 1.8 1 1 2 3 3 3 1 Ammonium Transporter Family Nuc_rec_co-act PF08815.10 ABX12095.1 - 0.052 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Nuclear receptor coactivator Ig_6 PF18452.1 ABX12096.1 - 0.19 11.4 0.0 13 5.5 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain Radical_SAM PF04055.21 ABX12097.1 - 2.7e-14 53.9 0.2 6.3e-14 52.7 0.1 1.6 2 0 0 2 2 2 1 Radical SAM superfamily IMPDH PF00478.25 ABX12097.1 - 0.0011 18.0 0.1 0.0017 17.5 0.1 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain HTH_5 PF01022.20 ABX12098.1 - 1.3e-11 44.2 0.4 2.5e-11 43.3 0.2 1.5 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABX12098.1 - 2.5e-06 27.4 0.0 3.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain B-block_TFIIIC PF04182.12 ABX12098.1 - 3.9e-05 23.7 0.1 5.6e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 ABX12098.1 - 9.9e-05 21.8 0.4 0.00017 21.1 0.4 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_45 PF14947.6 ABX12098.1 - 0.00035 20.5 0.9 0.00055 19.9 0.9 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_11 PF08279.12 ABX12098.1 - 0.00044 20.1 0.2 0.00065 19.6 0.2 1.3 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 ABX12098.1 - 0.0023 17.8 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 ABX12098.1 - 0.0024 17.7 0.0 0.0041 17.0 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 ABX12098.1 - 0.0025 17.7 0.1 0.0038 17.1 0.1 1.2 1 0 0 1 1 1 1 MarR family DUF4423 PF14394.6 ABX12098.1 - 0.0027 17.4 1.6 0.028 14.1 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) HTH_12 PF08461.10 ABX12098.1 - 0.0029 17.5 0.1 0.0051 16.7 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Phage_rep_O PF04492.13 ABX12098.1 - 0.0073 16.9 0.1 0.0095 16.5 0.1 1.2 1 0 0 1 1 1 1 Bacteriophage replication protein O PheRS_DBD1 PF18552.1 ABX12098.1 - 0.015 15.1 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 PheRS DNA binding domain 1 MSV199 PF10553.9 ABX12098.1 - 0.017 15.4 0.5 0.02 15.1 0.5 1.2 1 0 0 1 1 1 0 MSV199 domain HTH_29 PF13551.6 ABX12098.1 - 0.03 14.4 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Crp_2 PF13545.6 ABX12098.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ABX12098.1 - 0.046 14.1 0.2 0.091 13.1 0.1 1.5 1 1 0 1 1 1 0 Transcriptional regulator FaeA PF04703.12 ABX12098.1 - 0.15 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 FaeA-like protein HTH_1 PF00126.27 ABX12098.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family DprA_WH PF17782.1 ABX12098.1 - 0.22 11.7 0.0 0.33 11.1 0.0 1.2 1 0 0 1 1 1 0 DprA winged helix domain DUF3270 PF11674.8 ABX12100.1 - 0.17 12.1 2.8 10 6.4 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3270) RVT_3 PF13456.6 ABX12101.1 - 4.9e-13 49.0 0.0 5.8e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 ABX12101.1 - 8.5e-12 45.5 0.0 1e-11 45.2 0.0 1.1 1 0 0 1 1 1 1 RNase H HAD_SAK_1 PF10307.9 ABX12101.1 - 0.024 14.5 0.1 0.027 14.3 0.1 1.1 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins ATP-grasp_5 PF13549.6 ABX12102.1 - 1.4e-79 266.6 1.2 1.4e-79 266.6 1.2 1.9 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.6 ABX12102.1 - 5.9e-53 178.4 1.6 1.1e-52 177.5 0.8 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ABX12102.1 - 2e-23 83.1 2.1 5.4e-23 81.7 0.2 2.7 3 1 0 3 3 3 1 CoA binding domain CoA_binding PF02629.19 ABX12102.1 - 6.5e-08 33.2 3.6 1.1e-07 32.4 0.9 2.7 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.10 ABX12102.1 - 3.9e-05 23.3 1.9 3.9e-05 23.3 1.9 2.0 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 ABX12102.1 - 0.00094 18.7 0.3 0.0021 17.6 0.3 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 ABX12102.1 - 0.025 14.2 0.5 0.17 11.4 0.4 2.4 1 1 0 1 1 1 0 ATP-grasp domain HpaB_N PF11794.8 ABX12103.1 - 5.1e-94 314.9 0.0 9.1e-94 314.1 0.0 1.4 2 0 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 ABX12103.1 - 6.1e-74 247.5 0.1 8.1e-74 247.1 0.1 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Herpes_LP PF03363.13 ABX12103.1 - 0.05 13.4 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus leader protein Peptidase_S24 PF00717.23 ABX12104.1 - 8.6e-08 32.0 0.3 2.2e-07 30.7 0.1 1.8 2 0 0 2 2 2 1 Peptidase S24-like MscL PF01741.18 ABX12104.1 - 0.0053 17.0 0.4 0.023 15.0 0.0 2.1 2 0 0 2 2 2 1 Large-conductance mechanosensitive channel, MscL DZR PF12773.7 ABX12105.1 - 2e-07 30.9 8.4 7.5e-05 22.7 2.4 2.4 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.6 ABX12105.1 - 1.5e-06 27.8 5.8 1.5e-06 27.8 5.8 2.3 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 ABX12105.1 - 6.6e-05 23.6 2.0 0.07 13.9 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon family PRC PF05239.16 ABX12105.1 - 0.00028 20.9 0.1 0.00049 20.1 0.1 1.4 1 0 0 1 1 1 1 PRC-barrel domain zf-ribbon_3 PF13248.6 ABX12105.1 - 0.0038 16.6 3.3 0.0038 16.6 3.3 2.6 3 0 0 3 3 3 1 zinc-ribbon domain zf-B_box PF00643.24 ABX12105.1 - 0.026 14.7 6.9 0.88 9.8 0.2 3.1 3 0 0 3 3 3 0 B-box zinc finger Cript PF10235.9 ABX12105.1 - 0.075 13.6 0.6 1.3 9.7 0.0 2.8 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT GFA PF04828.14 ABX12105.1 - 0.087 13.2 2.5 26 5.2 0.2 3.5 3 1 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.10 ABX12105.1 - 0.16 11.7 0.0 0.16 11.7 0.0 3.6 3 1 0 3 3 3 0 A2L zinc ribbon domain Gin PF10764.9 ABX12105.1 - 0.26 11.3 0.1 0.26 11.3 0.1 3.2 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin zinc-ribbons_6 PF07191.12 ABX12105.1 - 0.77 9.8 9.8 4 7.5 0.7 3.1 2 1 0 2 2 2 0 zinc-ribbons zf-AD PF07776.15 ABX12105.1 - 1.5 9.1 5.7 2.6 8.3 0.1 2.9 3 1 0 3 3 3 0 Zinc-finger associated domain (zf-AD) zf-FPG_IleRS PF06827.14 ABX12105.1 - 1.6 8.7 6.9 33 4.5 0.1 3.6 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Nudix_N_2 PF14803.6 ABX12105.1 - 2.5 8.1 11.9 0.38 10.7 0.4 3.8 4 0 0 4 4 4 0 Nudix N-terminal Tnp_zf-ribbon_2 PF13842.6 ABX12105.1 - 3 8.7 6.9 45 5.0 0.1 3.3 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon zf-RRN7 PF11781.8 ABX12105.1 - 6.5 6.5 7.9 9.7 6.0 1.9 2.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 NOB1_Zn_bind PF08772.11 ABX12105.1 - 8.7 6.6 11.7 2.4 8.4 2.3 2.6 3 0 0 3 3 2 0 Nin one binding (NOB1) Zn-ribbon like Thioredoxin PF00085.20 ABX12106.1 - 2.3e-30 104.6 0.0 2.6e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ABX12106.1 - 2.3e-10 40.6 0.1 3.9e-06 27.1 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 ABX12106.1 - 8.4e-09 35.9 0.0 2.4e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 ABX12106.1 - 1.9e-05 24.4 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 ABX12106.1 - 3.4e-05 23.8 0.0 4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.6 ABX12106.1 - 4.3e-05 23.6 0.0 6.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 ABX12106.1 - 0.00042 20.2 0.0 0.00049 20.0 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 ABX12106.1 - 0.00083 19.1 0.1 0.0012 18.5 0.1 1.3 1 1 0 1 1 1 1 Redoxin HyaE PF07449.11 ABX12106.1 - 0.0038 17.2 0.0 0.0048 16.8 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 ABX12106.1 - 0.0053 16.2 0.0 0.0061 16.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF953 PF06110.11 ABX12106.1 - 0.0087 15.7 0.3 0.025 14.2 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.24 ABX12106.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF836 PF05768.14 ABX12106.1 - 0.14 12.6 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) zinc_ribbon_2 PF13240.6 ABX12107.1 - 2.7e-08 33.3 3.3 4.7e-08 32.5 3.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 ABX12107.1 - 8e-07 28.3 1.9 1.2e-06 27.6 1.9 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 ABX12107.1 - 3e-06 27.2 1.0 4.5e-06 26.6 1.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.9 ABX12107.1 - 8.3e-05 22.6 4.7 0.00053 20.0 4.9 1.9 1 1 1 2 2 2 2 Uncharacterised protein family UPF0547 zinc_ribbon_15 PF17032.5 ABX12107.1 - 8.8e-05 23.2 0.6 0.00012 22.8 0.6 1.2 1 0 0 1 1 1 1 zinc-ribbon family Nudix_N_2 PF14803.6 ABX12107.1 - 0.00026 20.8 4.2 0.12 12.3 0.2 2.3 2 0 0 2 2 2 2 Nudix N-terminal zf-NADH-PPase PF09297.11 ABX12107.1 - 0.018 14.7 4.1 0.76 9.5 0.2 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain A2L_zn_ribbon PF08792.10 ABX12107.1 - 0.023 14.4 3.4 1.5 8.6 0.3 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain RNA_POL_M_15KD PF02150.16 ABX12107.1 - 0.032 14.1 3.2 2.9 7.9 0.5 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf_UBZ PF18439.1 ABX12107.1 - 0.084 12.5 3.3 1.2 8.7 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger GFA PF04828.14 ABX12107.1 - 0.11 12.9 4.1 1.1 9.6 0.2 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme HypA PF01155.19 ABX12107.1 - 0.11 12.5 0.8 0.15 12.0 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RecR PF02132.15 ABX12107.1 - 0.12 11.9 1.4 3 7.5 1.4 2.2 1 1 0 1 1 1 0 RecR protein NRDD PF13597.6 ABX12107.1 - 0.14 10.9 0.6 0.17 10.6 0.6 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase YhfH PF14149.6 ABX12107.1 - 0.21 11.6 4.4 4.7 7.3 0.2 2.3 1 1 1 2 2 2 0 YhfH-like protein Prok-RING_1 PF14446.6 ABX12107.1 - 0.31 11.0 3.4 0.67 9.9 3.4 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 NOB1_Zn_bind PF08772.11 ABX12107.1 - 0.36 11.0 7.2 3.9 7.7 0.8 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like HscB_4_cys PF18256.1 ABX12107.1 - 0.73 9.7 4.2 5.7 6.8 0.1 2.3 1 1 1 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif zf-tcix PF14952.6 ABX12107.1 - 1.1 9.0 5.5 4.8 6.9 0.9 2.2 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding LisH_2 PF16045.5 ABX12107.1 - 3.7 6.7 8.5 5.3 6.2 0.7 2.9 3 0 0 3 3 3 0 LisH zinc_ribbon_2 PF13240.6 ABX12108.1 - 2.2e-08 33.6 4.6 3.5e-08 32.9 4.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 ABX12108.1 - 6.8e-05 22.8 1.5 9.5e-05 22.3 1.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 ABX12108.1 - 0.0002 20.7 4.1 0.00036 19.8 4.1 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 ABX12108.1 - 0.00075 20.2 0.7 0.0013 19.5 0.2 1.6 2 0 0 2 2 2 1 zinc-ribbon family PAH PF02671.21 ABX12108.1 - 0.15 12.2 0.5 0.15 12.2 0.5 1.6 2 0 0 2 2 2 0 Paired amphipathic helix repeat zf-NADH-PPase PF09297.11 ABX12108.1 - 0.4 10.4 3.6 5.6 6.7 0.1 2.3 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 ABX12108.1 - 2.7 8.0 6.7 5 7.1 1.4 2.2 2 0 0 2 2 2 0 Nudix N-terminal DnaJ_CXXCXGXG PF00684.19 ABX12109.1 - 0.0025 18.2 8.3 0.0047 17.3 8.3 1.5 1 1 0 1 1 1 1 DnaJ central domain DUF5351 PF17302.2 ABX12109.1 - 0.08 13.2 3.3 0.08 13.2 3.3 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5351) DZR PF12773.7 ABX12109.1 - 1.6 8.8 13.1 1.4 9.0 1.7 2.1 1 1 1 2 2 2 0 Double zinc ribbon Anti-TRAP PF15777.5 ABX12109.1 - 2.7 8.0 7.7 4.7 7.2 0.3 2.8 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Amidohydro_1 PF01979.20 ABX12110.1 - 2.7e-19 69.7 0.1 1.4e-18 67.4 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABX12110.1 - 3.9e-09 36.5 0.1 0.00047 19.8 0.0 3.3 3 1 0 3 3 3 3 Amidohydrolase family TatD_DNase PF01026.21 ABX12110.1 - 0.00015 21.3 0.1 0.00033 20.1 0.1 1.8 1 1 0 1 1 1 1 TatD related DNase Memo PF01875.17 ABX12111.1 - 1.4e-82 276.9 0.1 1.6e-82 276.7 0.1 1.0 1 0 0 1 1 1 1 Memo-like protein AMMECR1 PF01871.17 ABX12112.1 - 2.3e-51 173.7 0.0 2.6e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Radical_SAM PF04055.21 ABX12113.1 - 8.5e-14 52.3 0.8 2.9e-13 50.6 0.0 2.2 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.6 ABX12113.1 - 0.006 16.8 1.4 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain zf-4CXXC_R1 PF10497.9 ABX12113.1 - 0.27 11.5 6.0 2.6 8.3 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Rib_5-P_isom_A PF06026.14 ABX12114.1 - 1.1e-53 181.4 0.2 1.3e-53 181.2 0.2 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 ABX12114.1 - 0.002 18.1 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 DeoR C terminal sensor domain BLACT_WH PF17778.1 ABX12114.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain Flagellin_C PF00700.21 ABX12115.1 - 0.011 16.1 0.5 0.034 14.5 0.5 2.0 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Ribosomal_L37e PF01907.19 ABX12116.1 - 8.6e-21 73.9 11.6 9.5e-21 73.7 11.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L37e HypA PF01155.19 ABX12116.1 - 0.0033 17.4 1.1 0.0037 17.3 1.1 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 ABX12116.1 - 0.011 15.8 1.3 0.013 15.5 1.3 1.1 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_6 PF14599.6 ABX12116.1 - 0.02 14.9 2.0 0.029 14.4 2.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon zf-ribbon_3 PF13248.6 ABX12116.1 - 0.021 14.2 1.7 0.029 13.8 1.7 1.2 1 0 0 1 1 1 0 zinc-ribbon domain Cation_ATPase_N PF00690.26 ABX12116.1 - 0.033 13.9 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus zf-Mss51 PF13824.6 ABX12116.1 - 0.076 13.1 3.4 6.2 7.0 3.4 2.1 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_RNApol_7kD PF03604.13 ABX12116.1 - 0.078 12.7 8.2 0.079 12.7 3.1 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Rubredoxin_2 PF18073.1 ABX12116.1 - 0.41 10.4 5.8 7.3 6.4 0.1 2.5 2 1 0 2 2 2 0 Rubredoxin metal binding domain DUF2688 PF10892.8 ABX12116.1 - 2 7.9 6.8 2.1 7.9 4.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) LSM PF01423.22 ABX12117.1 - 3.3e-22 77.9 0.2 3.7e-22 77.8 0.2 1.0 1 0 0 1 1 1 1 LSM domain Creatininase PF02633.14 ABX12118.1 - 1.9e-49 168.3 0.0 2.4e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase Imm15 PF15561.6 ABX12118.1 - 0.061 13.5 0.9 0.22 11.7 0.9 1.7 1 1 0 1 1 1 0 Immunity protein 15 Amidase_3 PF01520.18 ABX12118.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase Formyl_trans_N PF00551.19 ABX12119.1 - 7.8e-44 149.6 0.0 1.3e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase ACT_6 PF13740.6 ABX12119.1 - 1.2e-06 28.4 0.1 3.2e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 ABX12119.1 - 0.019 15.5 1.5 0.053 14.1 0.0 2.5 2 1 0 3 3 3 0 ACT domain DUF4411 PF14367.6 ABX12119.1 - 0.022 14.7 1.1 0.05 13.5 1.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) PGM_PMM_I PF02878.16 ABX12120.1 - 7.1e-38 129.4 0.0 1.3e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 ABX12120.1 - 3.8e-25 88.5 0.0 8.2e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 ABX12120.1 - 1.6e-19 70.2 0.0 2.7e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 ABX12120.1 - 5e-10 39.4 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ribosomal_L7Ae PF01248.26 ABX12121.1 - 4.4e-25 87.2 0.1 5.3e-25 87.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 ABX12121.1 - 0.0017 18.2 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain DUF3055 PF11256.8 ABX12121.1 - 0.16 12.2 0.0 0.4 11.0 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3055) Ribosomal_S28e PF01200.18 ABX12122.1 - 3e-27 94.4 4.8 3.3e-27 94.3 4.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_L24e PF01246.20 ABX12123.1 - 3.4e-18 65.6 1.2 3.8e-18 65.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FLZ PF04570.14 ABX12123.1 - 0.0063 16.0 0.2 0.011 15.2 0.2 1.4 1 1 0 1 1 1 1 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 ABX12123.1 - 0.012 15.7 7.1 3.8 7.7 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Lar_restr_allev PF14354.6 ABX12123.1 - 0.014 15.8 0.2 0.015 15.6 0.2 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-FCS PF06467.14 ABX12123.1 - 0.76 9.8 5.5 0.19 11.7 2.4 1.7 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif NDK PF00334.19 ABX12124.1 - 1.4e-50 170.9 0.0 1.5e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase GTP_EFTU PF00009.27 ABX12125.1 - 7.2e-33 113.8 0.0 1.8e-32 112.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D4 PF14578.6 ABX12125.1 - 2.2e-22 78.7 0.0 8.2e-22 76.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 IF-2 PF11987.8 ABX12125.1 - 1.3e-21 76.6 1.4 4.3e-21 75.0 1.4 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 ABX12125.1 - 2.9e-08 33.8 0.4 1.4e-07 31.6 0.0 2.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ABX12125.1 - 1.7e-05 25.1 0.0 9.8e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.17 ABX12125.1 - 4e-05 23.5 0.0 0.00018 21.4 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Roc PF08477.13 ABX12125.1 - 7.7e-05 22.9 0.0 0.00024 21.3 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 ABX12125.1 - 0.00047 20.3 0.3 0.06 13.4 0.1 2.8 2 1 0 2 2 2 1 Dynamin family Ras PF00071.22 ABX12125.1 - 0.0059 16.2 0.0 0.033 13.8 0.0 2.2 1 1 0 1 1 1 1 Ras family cobW PF02492.19 ABX12125.1 - 0.027 14.1 0.1 2.8 7.5 0.0 2.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 ABX12125.1 - 0.068 12.6 0.0 0.25 10.8 0.0 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Peroxin-22 PF12827.7 ABX12125.1 - 0.098 12.6 0.0 0.36 10.8 0.0 2.0 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family Thioredoxin PF00085.20 ABX12126.1 - 4.5e-31 106.9 0.1 6.3e-31 106.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ABX12126.1 - 1.7e-08 34.9 0.2 5.8e-08 33.2 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ABX12126.1 - 1.6e-07 31.5 0.7 8.8e-07 29.2 0.1 2.1 2 1 0 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 ABX12126.1 - 3.6e-07 29.8 0.3 6.5e-07 29.0 0.3 1.4 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 ABX12126.1 - 3.8e-07 29.9 0.4 5.4e-07 29.4 0.4 1.3 1 1 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 ABX12126.1 - 4.1e-06 26.6 0.0 5.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin Phosducin PF02114.16 ABX12126.1 - 0.00021 20.4 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin_7 PF13899.6 ABX12126.1 - 0.00089 19.4 0.1 0.0015 18.7 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 ABX12126.1 - 0.001 19.0 0.1 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 ABX12126.1 - 0.0011 18.9 0.1 0.0018 18.2 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 ABX12126.1 - 0.0054 16.6 0.0 0.0054 16.6 0.0 1.4 2 0 0 2 2 2 1 F plasmid transfer operon protein HyaE PF07449.11 ABX12126.1 - 0.019 14.9 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 ABX12126.1 - 0.053 13.7 0.1 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 Glutaredoxin UAA PF08449.11 ABX12126.1 - 0.084 12.1 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 UAA transporter family He_PIG PF05345.12 ABX12127.1 - 1.9e-05 24.7 0.8 1.9e-05 24.7 0.8 3.0 3 0 0 3 3 3 1 Putative Ig domain fn3_5 PF06280.12 ABX12127.1 - 0.05 14.3 0.5 0.11 13.1 0.5 1.6 1 0 0 1 1 1 0 Fn3-like domain Occludin_ELL PF07303.13 ABX12127.1 - 0.45 11.3 13.3 1.5 9.6 0.6 3.2 3 0 0 3 3 3 0 Occludin homology domain Archease PF01951.16 ABX12128.1 - 4e-33 114.6 0.4 4.4e-33 114.4 0.4 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) RdgC PF04381.12 ABX12128.1 - 0.0021 17.4 0.1 0.0025 17.1 0.1 1.1 1 0 0 1 1 1 1 Putative exonuclease, RdgC Glyoxalase PF00903.25 ABX12129.1 - 0.044 14.0 0.0 0.11 12.7 0.0 1.5 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SNARE_assoc PF09335.11 ABX12130.1 - 1.2e-21 77.4 4.4 1.2e-21 77.4 4.4 1.4 1 1 0 1 1 1 1 SNARE associated Golgi protein DUF1059 PF06348.11 ABX12131.1 - 2.4e-18 66.1 0.6 2.7e-18 65.9 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) Sina PF03145.16 ABX12131.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Seven in absentia protein family tRNA-synt_His PF13393.6 ABX12132.1 - 1.4e-45 155.9 0.0 1.8e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 ABX12132.1 - 5.9e-13 49.2 0.2 2.4e-12 47.2 0.2 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ABX12132.1 - 2.4e-10 40.4 0.1 6.9e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 ABX12132.1 - 0.00024 20.6 0.0 0.00059 19.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) eIF-6 PF01912.18 ABX12133.1 - 4.8e-65 218.6 1.4 5.9e-65 218.4 1.4 1.1 1 0 0 1 1 1 1 eIF-6 family TssC PF17541.2 ABX12133.1 - 0.078 11.8 0.0 0.09 11.6 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Fer4_7 PF12838.7 ABX12134.1 - 6.3e-10 39.5 3.9 5.2e-05 23.8 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 ABX12134.1 - 6.7e-10 38.4 11.9 5.6e-06 26.0 1.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 ABX12134.1 - 2.3e-08 34.0 3.7 5.6e-08 32.8 3.6 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 ABX12134.1 - 1.7e-07 32.0 5.8 0.00077 20.3 2.4 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 ABX12134.1 - 3e-07 30.5 4.8 0.00068 19.7 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 ABX12134.1 - 3.5e-07 30.6 0.5 0.017 15.6 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ABX12134.1 - 4.9e-07 29.8 7.6 5.8e-06 26.4 8.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABX12134.1 - 4.7e-06 26.4 12.5 0.0089 16.1 3.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 ABX12134.1 - 0.00042 20.6 6.3 0.036 14.6 1.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 ABX12134.1 - 0.00052 20.5 5.3 0.024 15.2 7.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 ABX12134.1 - 0.00063 19.7 11.6 0.049 13.8 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 ABX12134.1 - 0.00089 19.4 6.8 0.0015 18.7 5.1 2.0 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 ABX12134.1 - 0.0051 17.6 0.7 4.6 8.1 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 ABX12134.1 - 0.008 16.7 14.1 0.16 12.5 2.9 2.6 2 1 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 ABX12134.1 - 0.059 14.3 14.9 1.5 9.9 6.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 ABX12134.1 - 0.18 12.6 14.0 0.13 13.1 3.1 2.8 3 1 0 3 3 2 0 4Fe-4S single cluster domain Fer4_7 PF12838.7 ABX12135.1 - 9.2e-11 42.2 1.5 3.5e-05 24.3 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 ABX12135.1 - 1.4e-10 40.5 6.9 5.9e-06 25.9 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 ABX12135.1 - 4.2e-10 39.6 16.2 4.5e-07 29.9 7.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 ABX12135.1 - 6.2e-09 36.7 3.3 4.6e-05 24.3 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 ABX12135.1 - 1.2e-07 31.8 4.8 0.0051 16.9 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ABX12135.1 - 2.7e-07 30.6 8.2 1.1e-06 28.7 8.3 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ABX12135.1 - 2.9e-07 30.8 16.0 2.3e-06 28.0 9.5 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABX12135.1 - 1.3e-06 28.2 10.0 0.0018 18.3 3.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 ABX12135.1 - 2.4e-06 27.3 11.9 0.0061 16.6 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 ABX12135.1 - 3.5e-06 27.4 4.8 1.4e-05 25.6 5.3 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 ABX12135.1 - 1.7e-05 25.0 5.9 0.016 15.7 1.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 ABX12135.1 - 0.0017 19.2 0.8 1.9 9.4 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 ABX12135.1 - 0.0046 17.5 10.1 0.67 10.5 0.3 2.7 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 ABX12135.1 - 0.005 17.0 9.2 0.042 14.0 1.7 2.3 1 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 ABX12135.1 - 0.01 16.8 16.9 0.043 14.8 7.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain DNA_pol3_delta2 PF13177.6 ABX12136.1 - 7.7e-16 58.3 0.1 4.5e-12 46.1 0.2 2.5 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 ABX12136.1 - 2.1e-12 47.6 0.6 5.6e-12 46.2 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 ABX12136.1 - 8.8e-11 42.1 1.0 2.1e-10 40.8 0.3 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_16 PF13191.6 ABX12136.1 - 2.7e-05 24.6 0.0 8.2e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 ABX12136.1 - 9.7e-05 22.2 0.2 0.0003 20.6 0.2 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 ABX12136.1 - 0.00023 21.5 1.4 0.034 14.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 ABX12136.1 - 0.00025 20.8 0.1 0.00075 19.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 ABX12136.1 - 0.00031 20.7 0.0 0.0056 16.6 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_3 PF07726.11 ABX12136.1 - 0.00061 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 ABX12136.1 - 0.0011 19.3 0.1 0.0031 17.8 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 ABX12136.1 - 0.0035 16.7 0.0 0.41 10.0 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 ABX12136.1 - 0.0045 17.0 0.0 0.54 10.2 0.0 2.5 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit TniB PF05621.11 ABX12136.1 - 0.0054 16.2 0.1 0.47 9.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 ABX12136.1 - 0.0063 16.3 1.8 0.055 13.2 0.1 2.1 1 1 1 2 2 2 1 AAA domain PTPlike_phytase PF14566.6 ABX12136.1 - 0.011 15.9 0.1 0.098 12.8 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate DEAD PF00270.29 ABX12136.1 - 0.015 15.1 1.0 0.25 11.1 0.1 2.6 1 1 0 2 2 2 0 DEAD/DEAH box helicase T2SSE PF00437.20 ABX12136.1 - 0.028 13.5 0.1 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.14 ABX12136.1 - 0.032 14.2 0.3 0.27 11.2 0.3 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ABX12136.1 - 0.086 13.4 0.5 0.31 11.6 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ABX12136.1 - 0.16 12.3 1.0 4.8 7.5 0.1 2.8 2 1 1 3 3 3 0 AAA domain Sld5 PF05916.11 ABX12137.1 - 6.4e-08 33.0 0.4 8.7e-08 32.6 0.4 1.2 1 0 0 1 1 1 1 GINS complex protein DUF620 PF04788.12 ABX12137.1 - 0.0023 17.4 0.5 0.0032 16.9 0.2 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF620) MCM PF00493.23 ABX12138.1 - 1.4e-92 308.9 0.0 2e-92 308.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ABX12138.1 - 2.4e-35 121.1 0.3 4.3e-35 120.3 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ABX12138.1 - 1.8e-23 82.8 0.4 3.9e-23 81.7 0.4 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ABX12138.1 - 4.2e-12 46.6 0.6 1.3e-11 44.9 0.6 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ABX12138.1 - 3.7e-06 26.5 0.0 0.00026 20.4 0.0 2.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ABX12138.1 - 8e-06 25.9 0.0 0.00031 20.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ABX12138.1 - 0.0022 17.8 0.0 0.0072 16.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 ABX12139.1 - 1e-26 93.8 0.0 2.7e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ABX12139.1 - 1.2e-11 44.9 0.8 1.9e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ABX12139.1 - 4.5e-11 43.1 1.7 9.9e-10 38.7 0.1 3.4 3 1 0 3 3 3 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 ABX12139.1 - 1.1e-09 38.7 2.4 2e-09 37.9 0.8 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 ABX12139.1 - 5.3e-07 29.6 0.5 3e-05 24.0 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.9 ABX12139.1 - 0.00046 20.0 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DUF4332 PF14229.6 ABX12139.1 - 0.016 15.4 0.4 0.065 13.5 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4332) DnaB_C PF03796.15 ABX12139.1 - 0.023 14.1 0.7 0.048 13.0 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 ABX12139.1 - 0.032 13.3 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 ABX12139.1 - 0.14 11.7 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Glycos_transf_4 PF00953.21 ABX12140.1 - 9.9e-28 97.1 15.0 9.9e-28 97.1 15.0 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 4 ATP-synt_B PF00430.18 ABX12140.1 - 0.21 11.7 0.1 0.45 10.6 0.1 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Hexapep PF00132.24 ABX12141.1 - 6e-26 89.2 16.1 1.1e-10 40.8 0.9 4.4 4 1 1 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ABX12141.1 - 6.6e-19 67.4 10.6 3.1e-10 39.6 2.2 4.3 3 1 1 4 4 4 4 Hexapeptide repeat of succinyl-transferase Trm112p PF03966.16 ABX12142.1 - 6.4e-08 33.1 0.4 2.1e-07 31.4 0.4 1.9 1 1 0 1 1 1 1 Trm112p-like protein DUF2719 PF10891.8 ABX12142.1 - 0.13 12.1 0.1 0.41 10.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2719) GFO_IDH_MocA PF01408.22 ABX12143.1 - 1.6e-26 93.5 0.2 5.4e-26 91.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ABX12143.1 - 8.3e-08 32.2 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain IlvN PF07991.12 ABX12143.1 - 0.041 13.5 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Peptidase_M73 PF12389.8 ABX12143.1 - 0.078 12.8 0.6 0.21 11.4 0.1 1.9 1 1 0 1 1 1 0 Camelysin metallo-endopeptidase Aminotran_4 PF01063.19 ABX12144.1 - 1.2e-45 156.0 0.0 1.5e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV DUF22 PF01629.16 ABX12144.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF22 HATPase_c PF02518.26 ABX12145.1 - 7.2e-19 68.4 1.8 1e-18 67.9 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABX12145.1 - 9.9e-13 47.9 0.0 4.4e-12 45.8 0.0 2.2 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 ABX12145.1 - 3.3e-05 23.7 3.6 3.3e-05 23.7 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RE_HindIII PF09518.10 ABX12145.1 - 0.02 14.1 1.4 0.048 12.9 1.4 1.8 1 0 0 1 1 1 0 HindIII restriction endonuclease HAMP PF00672.25 ABX12145.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 HAMP domain HisKA_4TM PF16926.5 ABX12145.1 - 0.23 11.0 1.2 2.7 7.5 0.4 2.4 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase Phosphonate-bd PF12974.7 ABX12146.1 - 4.8e-47 160.6 0.0 6.4e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Response_reg PF00072.24 ABX12147.1 - 6.7e-22 77.8 0.4 7.6e-22 77.6 0.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.19 ABX12147.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain CTP_transf_like PF01467.26 ABX12148.1 - 0.0036 17.5 0.0 0.0077 16.4 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like NAD_binding_1 PF00175.21 ABX12149.1 - 2.6e-13 50.6 0.0 4.8e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ABX12149.1 - 4.6e-08 33.3 0.0 7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Methyltransf_34 PF11312.8 ABX12149.1 - 0.039 13.2 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase NAD_binding_6 PF08030.12 ABX12149.1 - 0.17 12.0 0.2 0.57 10.3 0.1 1.9 1 1 1 2 2 2 0 Ferric reductase NAD binding domain ORC2 PF04084.14 ABX12149.1 - 0.22 10.4 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 2 HEAT_2 PF13646.6 ABX12150.1 - 3.4e-18 65.8 0.1 2.7e-11 43.7 0.1 2.3 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 ABX12150.1 - 3.1e-11 42.5 0.1 0.058 13.7 0.0 4.4 4 0 0 4 4 4 4 HEAT repeat HEAT_EZ PF13513.6 ABX12150.1 - 2.5e-08 34.2 0.1 0.7 10.5 0.0 4.2 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 ABX12150.1 - 6.9e-05 22.9 2.0 0.94 9.5 0.1 3.3 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ABX12150.1 - 0.0075 16.8 0.4 4 8.1 0.0 2.9 1 1 2 3 3 3 2 Vacuolar 14 Fab1-binding region MgtE_N PF03448.17 ABX12150.1 - 0.085 13.5 2.1 0.82 10.3 0.1 3.0 2 1 0 2 2 2 0 MgtE intracellular N domain Cohesin_HEAT PF12765.7 ABX12150.1 - 0.36 11.2 2.6 16 5.9 0.2 3.2 3 1 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Alba PF01918.21 ABX12151.1 - 1.3e-11 44.1 0.2 2e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 ABX12151.1 - 0.055 13.4 0.4 3.5 7.6 0.0 2.1 1 1 1 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P PEP_mutase PF13714.6 ABX12152.1 - 1e-50 172.5 0.0 1.2e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 ABX12152.1 - 2.5e-15 56.0 0.0 4e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 ABX12152.1 - 0.017 14.5 0.1 0.22 10.9 0.0 2.5 2 1 1 3 3 3 0 Ketopantoate hydroxymethyltransferase NOP5NT PF08156.13 ABX12152.1 - 0.3 11.5 1.3 0.9 10.0 1.3 1.8 1 0 0 1 1 1 0 NOP5NT (NUC127) domain PadR PF03551.14 ABX12153.1 - 1.2e-11 44.4 0.3 2.4e-11 43.4 0.3 1.6 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.6 ABX12153.1 - 7.8e-07 29.0 3.3 4.4e-05 23.4 0.1 2.6 3 0 0 3 3 3 2 Winged helix-turn-helix RTP PF02334.16 ABX12153.1 - 0.00082 20.0 0.9 0.0071 17.0 0.1 2.3 1 1 1 2 2 2 1 Replication terminator protein Mrr_N PF14338.6 ABX12153.1 - 0.0013 18.8 0.9 0.019 15.1 0.1 2.6 3 0 0 3 3 3 1 Mrr N-terminal domain DisA-linker PF10635.9 ABX12153.1 - 0.0056 16.4 1.6 0.043 13.6 1.1 2.3 2 1 0 2 2 2 1 DisA bacterial checkpoint controller linker region DUF4364 PF14277.6 ABX12153.1 - 0.013 15.3 0.5 0.039 13.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Pox_E6 PF04656.12 ABX12153.1 - 0.014 13.8 0.0 0.019 13.5 0.0 1.1 1 0 0 1 1 1 0 Pox virus E6 protein DUF4423 PF14394.6 ABX12153.1 - 0.042 13.6 2.0 0.39 10.4 2.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) Stork_head PF10264.9 ABX12153.1 - 0.063 13.4 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Hemocyanin_M PF00372.19 ABX12153.1 - 0.068 12.3 0.2 0.09 12.0 0.2 1.1 1 0 0 1 1 1 0 Hemocyanin, copper containing domain FAM86 PF14904.6 ABX12153.1 - 0.16 12.0 0.6 2.2 8.4 0.0 2.5 2 1 1 3 3 3 0 Family of unknown function FAD_binding_2 PF00890.24 ABX12154.1 - 1.8e-98 330.4 0.4 2.4e-98 329.9 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ABX12154.1 - 1.3e-35 122.1 1.0 2.2e-35 121.4 1.0 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 ABX12154.1 - 8.2e-07 28.5 0.0 0.00037 19.8 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ABX12154.1 - 0.00015 21.1 0.5 0.00065 19.0 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 ABX12154.1 - 0.0013 18.2 0.4 0.017 14.5 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 ABX12154.1 - 0.01 15.0 1.6 0.056 12.5 1.6 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ABX12154.1 - 0.16 11.0 0.2 0.28 10.2 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Sdh_cyt PF01127.22 ABX12155.1 - 5.3e-08 32.9 4.7 8.4e-08 32.3 4.1 1.6 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 ABX12155.1 - 0.021 14.9 3.8 0.077 13.1 0.0 2.1 2 0 0 2 2 2 0 Fumarate reductase subunit D Sdh_cyt PF01127.22 ABX12156.1 - 1.3e-07 31.6 4.2 1.7e-07 31.3 4.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 ABX12156.1 - 0.014 15.5 3.4 0.019 15.1 3.4 1.2 1 0 0 1 1 1 0 Fumarate reductase subunit D Ferric_reduct PF01794.19 ABX12156.1 - 0.19 11.9 4.5 0.29 11.3 4.5 1.5 1 1 0 1 1 1 0 Ferric reductase like transmembrane component Fer2_3 PF13085.6 ABX12157.1 - 1.4e-31 108.7 0.0 2.7e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 ABX12157.1 - 1.7e-11 44.4 4.6 2e-11 44.2 2.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 ABX12157.1 - 5.3e-10 39.3 2.5 5.3e-10 39.3 2.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABX12157.1 - 3.3e-09 37.2 12.6 1.1e-07 32.3 3.3 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 ABX12157.1 - 1.1e-08 35.5 11.9 1.3e-07 32.0 2.5 2.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ABX12157.1 - 1.2e-07 31.8 5.9 1.6e-07 31.3 2.2 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 ABX12157.1 - 3.5e-07 31.0 2.4 3.5e-07 31.0 2.4 2.1 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 ABX12157.1 - 3.1e-05 24.1 6.8 0.023 14.9 0.2 2.9 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.27 ABX12157.1 - 8.3e-05 22.5 0.9 0.00018 21.4 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 ABX12157.1 - 0.00015 21.4 1.7 0.00015 21.4 1.7 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 ABX12157.1 - 0.018 15.1 4.1 0.018 15.1 4.1 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_2 PF12797.7 ABX12157.1 - 0.024 14.7 2.1 0.024 14.7 2.1 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_4 PF12800.7 ABX12157.1 - 0.12 12.9 1.3 0.12 12.9 1.3 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_21 PF14697.6 ABX12157.1 - 0.19 11.9 14.0 0.17 12.1 8.5 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 ABX12157.1 - 0.97 10.5 21.7 0.37 11.8 4.6 3.2 3 1 0 3 3 3 0 4Fe-4S binding domain Uteroglobin PF01099.17 ABX12157.1 - 1.2 9.5 3.3 7.5 7.0 0.0 2.8 3 0 0 3 3 3 0 Uteroglobin family FeS_assembly_P PF01883.19 ABX12158.1 - 6.3e-16 58.3 0.1 9e-16 57.8 0.1 1.3 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein HMA PF00403.26 ABX12158.1 - 0.23 11.9 1.4 0.48 10.9 0.1 2.0 2 1 0 2 2 2 0 Heavy-metal-associated domain Lyase_1 PF00206.20 ABX12159.1 - 4.1e-51 174.2 0.0 6.3e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 ABX12159.1 - 7.6e-12 45.8 0.1 4.4e-11 43.4 0.0 2.2 2 1 0 2 2 2 1 Argininosuccinate lyase C-terminal Mitofilin PF09731.9 ABX12160.1 - 0.056 12.3 23.1 0.077 11.8 23.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Phosphodiest PF01663.22 ABX12160.1 - 0.07 12.7 1.3 0.089 12.4 1.3 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase FIVAR PF07554.13 ABX12160.1 - 0.96 10.3 21.7 0.69 10.7 11.4 3.1 2 1 1 3 3 3 0 FIVAR domain V_ATPase_I PF01496.19 ABX12160.1 - 1.2 6.9 7.2 1.6 6.6 7.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 ABX12160.1 - 3.1 6.4 5.1 3.9 6.1 5.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Borrelia_P83 PF05262.11 ABX12160.1 - 4.1 5.8 20.1 4.3 5.7 20.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein GlutR_N PF05201.15 ABX12161.1 - 4.5e-24 84.9 0.0 7.8e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 ABX12161.1 - 4.6e-21 75.3 1.0 2.4e-20 73.0 0.1 2.4 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Staph_opine_DH PF10100.9 ABX12161.1 - 0.093 11.3 0.0 0.18 10.4 0.0 1.5 1 0 0 1 1 1 0 Staphylopine dehydrogenase Rotamase_2 PF13145.6 ABX12161.1 - 0.11 13.4 0.5 0.4 11.5 0.1 2.0 2 1 0 2 2 2 0 PPIC-type PPIASE domain DUF1059 PF06348.11 ABX12162.1 - 7.6e-09 35.7 0.1 8.7e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) AAA_lid_9 PF17871.1 ABX12162.1 - 0.04 13.8 0.1 0.044 13.7 0.1 1.1 1 0 0 1 1 1 0 AAA lid domain NAD_binding_1 PF00175.21 ABX12163.1 - 3.1e-11 43.9 0.0 6.3e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ABX12163.1 - 5.7e-08 33.0 0.0 9.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Methyltransf_34 PF11312.8 ABX12163.1 - 0.009 15.3 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase NAD_binding_6 PF08030.12 ABX12163.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Inositol_P PF00459.25 ABX12164.1 - 1.3e-27 97.0 0.0 1.4e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 ABX12164.1 - 0.0006 19.3 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Pox_VLTF3 PF04947.14 ABX12164.1 - 0.06 13.1 0.6 11 5.7 0.0 2.4 3 0 0 3 3 3 0 Poxvirus Late Transcription Factor VLTF3 like AAA PF00004.29 ABX12166.1 - 7.1e-13 49.1 0.0 1.6e-12 48.0 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ABX12166.1 - 1.6e-07 31.2 0.0 3.5e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 ABX12166.1 - 9.8e-06 25.6 0.1 3.7e-05 23.7 0.0 2.0 2 1 0 2 2 2 1 Rad17 P-loop domain TIP49 PF06068.13 ABX12166.1 - 6.1e-05 22.4 0.1 0.00013 21.3 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 ABX12166.1 - 0.0012 19.3 0.0 0.0028 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 ABX12166.1 - 0.0019 18.2 0.0 0.0039 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ABX12166.1 - 0.0024 17.8 0.0 0.0064 16.4 0.0 1.7 1 0 0 1 1 1 1 NTPase AAA_18 PF13238.6 ABX12166.1 - 0.0029 18.1 0.0 0.0074 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 ABX12166.1 - 0.0048 17.0 0.0 0.0081 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 ABX12166.1 - 0.027 13.9 0.1 0.084 12.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ABX12166.1 - 0.032 14.5 0.0 0.34 11.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain ResIII PF04851.15 ABX12166.1 - 0.035 14.1 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 ABX12166.1 - 0.048 13.2 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 ABX12166.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ABX12166.1 - 0.061 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RFC1 PF08519.12 ABX12166.1 - 0.071 13.3 0.7 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain Zeta_toxin PF06414.12 ABX12166.1 - 0.081 12.2 0.0 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 ABX12166.1 - 0.094 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ABX12166.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 ABX12166.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ABX12166.1 - 0.16 11.7 0.0 0.87 9.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ABX12166.1 - 0.23 11.0 0.1 0.44 10.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain Myticin-prepro PF10690.9 ABX12167.1 - 0.083 13.1 5.8 0.12 12.6 5.8 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Carboxyl_trans PF01039.22 ABX12168.1 - 2e-184 613.9 0.1 2.2e-184 613.7 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 ABX12168.1 - 3.6e-06 26.7 0.0 7.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) CPSase_L_D2 PF02786.17 ABX12169.1 - 4.6e-70 235.4 0.2 7e-70 234.8 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ABX12169.1 - 1.1e-46 157.9 0.0 2.2e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ABX12169.1 - 5e-34 116.6 0.0 9.9e-34 115.7 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.22 ABX12169.1 - 3.7e-10 39.6 0.2 7.8e-10 38.6 0.2 1.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ABX12169.1 - 1.8e-08 34.1 0.3 4.3e-08 32.9 0.3 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 ABX12169.1 - 4.9e-08 33.2 0.1 8.8e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 ABX12169.1 - 5.8e-08 32.6 0.0 3.3e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 ABX12169.1 - 0.00011 21.9 0.1 0.00025 20.7 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 ABX12169.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 ABX12169.1 - 0.036 13.5 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 ABX12169.1 - 0.046 13.0 0.0 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp DUF3182 PF11379.8 ABX12169.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Biotin_lipoyl PF00364.22 ABX12170.1 - 8.1e-18 64.0 5.0 8.1e-18 64.0 5.0 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ABX12170.1 - 9.5e-16 57.4 3.4 2.9e-08 33.4 0.3 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 ABX12170.1 - 1.9e-05 24.0 1.7 0.25 10.5 0.0 2.9 1 1 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ABX12170.1 - 2.7e-05 24.8 0.3 0.44 11.3 0.0 2.6 3 0 0 3 3 3 2 HlyD family secretion protein QRPTase_N PF02749.16 ABX12170.1 - 0.00019 21.4 0.7 0.072 13.2 0.1 2.3 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, N-terminal domain Peptidase_M23 PF01551.22 ABX12170.1 - 0.0049 17.1 1.9 1.5 9.1 0.1 2.6 2 1 1 3 3 3 2 Peptidase family M23 PTS_EIIA_1 PF00358.20 ABX12170.1 - 0.005 16.6 0.9 0.51 10.1 0.1 2.5 1 1 1 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 ABX12170.1 - 0.0085 16.0 2.8 0.043 13.8 2.8 2.1 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 ABX12170.1 - 0.011 15.6 3.0 0.012 15.5 1.6 1.9 2 1 0 2 2 2 0 Glycine cleavage H-protein eIF-1a PF01176.19 ABX12170.1 - 0.054 13.3 0.2 1 9.2 0.0 2.7 2 1 0 2 2 2 0 Translation initiation factor 1A / IF-1 DUF2118 PF09891.9 ABX12170.1 - 0.07 13.1 2.1 0.11 12.4 0.4 2.2 2 2 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) PYNP_C PF07831.13 ABX12170.1 - 0.07 12.8 1.3 3.9 7.2 0.0 2.9 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain PASTA PF03793.19 ABX12170.1 - 0.13 12.2 1.0 3.6 7.5 0.3 2.5 2 0 0 2 2 2 0 PASTA domain AhpC-TSA PF00578.21 ABX12171.1 - 3.7e-32 110.9 0.0 4.3e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ABX12171.1 - 3.5e-22 78.7 0.0 4e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 ABX12171.1 - 0.00091 19.1 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA_2 PF13911.6 ABX12171.1 - 0.014 15.5 0.0 0.048 13.8 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme Oxidored_q4 PF00507.19 ABX12172.1 - 2.3e-18 66.2 0.4 2.9e-18 65.8 0.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF3697 PF12478.8 ABX12172.1 - 0.0092 16.1 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 MPS-4 PF17523.2 ABX12172.1 - 0.089 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 NCE101 PF11654.8 ABX12172.1 - 0.13 12.0 0.1 0.39 10.5 0.1 1.8 1 0 0 1 1 1 0 Non-classical export protein 1 Oxidored_q6 PF01058.22 ABX12173.1 - 7e-25 87.4 0.1 9.7e-25 86.9 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_30kDa PF00329.19 ABX12174.1 - 1.7e-32 112.6 0.0 2.1e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Complex1_49kDa PF00346.19 ABX12175.1 - 6.7e-75 251.7 0.0 4.5e-72 242.4 0.0 2.1 1 1 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NADHdh PF00146.21 ABX12176.1 - 1.3e-95 320.1 21.6 2e-95 319.6 21.6 1.2 1 0 0 1 1 1 1 NADH dehydrogenase NDUF_B12 PF08122.12 ABX12176.1 - 0.061 13.4 0.5 0.061 13.4 0.5 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Fer4 PF00037.27 ABX12177.1 - 7.8e-12 44.5 10.8 3.2e-09 36.2 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 ABX12177.1 - 7e-09 35.7 18.3 1.6e-05 24.9 11.2 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABX12177.1 - 9.3e-09 35.7 9.2 1.5e-08 35.1 9.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 ABX12177.1 - 2.8e-08 33.8 20.3 4.9e-06 26.6 10.7 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ABX12177.1 - 3.6e-07 30.3 7.4 6.2e-07 29.5 7.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ABX12177.1 - 2.4e-06 27.9 2.6 0.0046 17.4 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 ABX12177.1 - 1e-05 25.3 9.8 0.0016 18.4 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 ABX12177.1 - 2e-05 24.5 11.8 4.3e-05 23.4 1.7 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_4 PF12800.7 ABX12177.1 - 8e-05 22.8 7.9 0.012 16.0 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 ABX12177.1 - 0.0011 19.6 4.4 0.22 12.3 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_16 PF13484.6 ABX12177.1 - 0.0013 19.7 10.0 0.0049 17.8 0.3 2.4 1 1 2 3 3 3 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 ABX12177.1 - 0.0017 18.8 10.8 0.026 15.1 0.8 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 ABX12177.1 - 0.0024 18.4 3.9 0.15 12.6 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 ABX12177.1 - 0.011 16.6 4.1 0.011 16.6 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 ABX12177.1 - 0.12 12.5 9.1 0.13 12.4 1.1 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 ABX12177.1 - 2.8 8.9 11.3 0.7 10.8 0.9 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain Oxidored_q3 PF00499.20 ABX12178.1 - 3.3e-24 85.3 10.1 3.3e-24 85.3 10.1 1.3 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4040 PF13244.6 ABX12178.1 - 0.012 15.8 10.6 0.012 15.8 10.6 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4040) Oxidored_q2 PF00420.24 ABX12179.1 - 2.9e-21 75.1 5.8 3.8e-21 74.7 5.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L VPDSG-CTERM PF18205.1 ABX12179.1 - 0.41 10.5 6.4 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 VPDSG-CTERM motif Proton_antipo_M PF00361.20 ABX12180.1 - 3e-63 213.8 25.0 3e-63 213.8 25.0 1.7 1 1 1 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 ABX12180.1 - 0.00027 21.0 3.3 0.00031 20.8 0.0 2.8 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_M PF00361.20 ABX12181.1 - 1.2e-59 201.9 35.9 1.6e-54 185.1 27.7 3.1 3 0 0 3 3 3 2 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 ABX12181.1 - 3.3e-13 49.5 1.9 3.3e-13 49.5 1.9 3.0 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q2 PF00420.24 ABX12181.1 - 0.62 9.7 13.9 0.057 13.0 0.3 4.6 4 1 0 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Proton_antipo_M PF00361.20 ABX12182.1 - 3.5e-68 230.0 25.8 3.5e-68 230.0 25.8 2.5 2 1 1 3 3 3 2 Proton-conducting membrane transporter polyprenyl_synt PF00348.17 ABX12183.1 - 1.8e-47 161.6 0.0 2.5e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase TENA_THI-4 PF03070.16 ABX12184.1 - 4.9e-17 62.4 0.3 5.9e-17 62.2 0.3 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.6 ABX12184.1 - 1e-14 54.7 0.0 1.3e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Iron-containing redox enzyme Pribosyltran PF00156.27 ABX12185.1 - 3.4e-16 59.2 0.5 4.6e-16 58.7 0.5 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ABX12185.1 - 0.00031 20.3 0.3 0.00041 19.9 0.3 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 ABX12185.1 - 0.00032 20.3 1.1 0.0005 19.6 0.3 1.7 2 1 1 3 3 3 1 Phosphoribosyl transferase NPV_P10 PF05531.12 ABX12185.1 - 0.056 13.9 1.8 0.11 13.0 1.8 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Peptidase_M50 PF02163.22 ABX12187.1 - 1.6e-11 44.0 14.3 1.9e-07 30.6 0.9 2.7 1 1 1 2 2 2 2 Peptidase family M50 Acetyltransf_1 PF00583.25 ABX12188.1 - 4.2e-19 68.9 0.1 5.5e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ABX12188.1 - 6.2e-14 52.2 1.2 7.9e-14 51.8 0.5 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABX12188.1 - 4.7e-13 49.2 0.1 7.1e-13 48.6 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ABX12188.1 - 2.4e-08 33.8 0.1 9.5e-08 31.9 0.0 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 ABX12188.1 - 0.002 17.8 0.0 0.0074 16.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ABX12188.1 - 0.0069 16.0 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase DUF4821 PF16092.5 ABX12188.1 - 0.0074 15.9 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4821) Acetyltransf_9 PF13527.7 ABX12188.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ABX12188.1 - 0.015 16.0 0.0 0.019 15.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ABX12188.1 - 0.029 14.5 0.2 0.034 14.3 0.2 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ABX12188.1 - 0.08 12.4 0.2 0.15 11.5 0.2 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 ABX12188.1 - 0.082 13.0 0.1 0.15 12.2 0.1 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Phage_holin_3_6 PF07332.11 ABX12189.1 - 0.029 14.4 1.9 0.033 14.2 1.9 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 ABX12189.1 - 1.1 8.0 3.1 1.2 7.8 3.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Met_10 PF02475.16 ABX12190.1 - 4.7e-56 189.7 0.2 5.7e-56 189.4 0.2 1.1 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 ABX12190.1 - 4.2e-05 22.9 0.0 6.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 ABX12190.1 - 8.9e-05 22.0 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ABX12190.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 ABX12190.1 - 0.0032 17.1 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 ABX12190.1 - 0.0047 16.6 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 ABX12190.1 - 0.038 13.9 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 ABX12190.1 - 0.083 13.6 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.27 ABX12191.1 - 2.4e-39 135.0 0.7 3.3e-18 66.5 0.1 2.7 2 0 0 2 2 2 2 ABC transporter Fer4 PF00037.27 ABX12191.1 - 3e-09 36.3 11.7 6.7e-09 35.2 5.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain RLI PF04068.15 ABX12191.1 - 5e-09 35.8 2.1 5e-09 35.8 2.1 1.8 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 ABX12191.1 - 2.8e-08 33.5 7.0 0.0011 18.4 0.5 3.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4_6 PF12837.7 ABX12191.1 - 2.1e-07 30.7 14.6 3.9e-07 29.9 5.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 ABX12191.1 - 9.2e-07 28.6 1.8 9.2e-07 28.6 1.8 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 ABX12191.1 - 5.9e-06 26.3 0.2 0.025 14.5 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase Fer4_21 PF14697.6 ABX12191.1 - 1.6e-05 24.9 12.2 3.1e-05 24.0 12.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 ABX12191.1 - 4.6e-05 23.4 1.3 4.6e-05 23.4 1.3 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABX12191.1 - 5.7e-05 23.6 9.7 0.00013 22.5 9.7 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain AAA_21 PF13304.6 ABX12191.1 - 0.0003 20.7 2.6 3 7.6 0.6 4.3 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABX12191.1 - 0.0046 16.7 0.6 0.59 9.9 0.1 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ABX12191.1 - 0.0046 17.3 0.1 0.14 12.5 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain Fer4_16 PF13484.6 ABX12191.1 - 0.0067 17.3 10.3 0.01 16.8 1.5 2.6 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 ABX12191.1 - 0.011 15.8 9.8 0.029 14.5 9.9 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain SbcCD_C PF13558.6 ABX12191.1 - 0.014 15.6 0.2 10 6.5 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 ABX12191.1 - 0.015 15.4 2.0 0.58 10.3 1.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase Fer4_4 PF12800.7 ABX12191.1 - 0.024 15.1 1.6 0.024 15.1 1.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_15 PF13175.6 ABX12191.1 - 0.025 14.3 1.7 4.6 6.8 0.7 2.7 2 1 1 3 3 3 0 AAA ATPase domain Fer4_3 PF12798.7 ABX12191.1 - 0.031 15.2 4.9 0.031 15.2 4.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Rad17 PF03215.15 ABX12191.1 - 0.035 14.0 0.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 ABX12191.1 - 0.038 14.0 0.1 5 7.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 ABX12191.1 - 0.088 13.2 0.1 2.3 8.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 ABX12191.1 - 0.11 11.7 1.7 6.1 5.9 0.3 2.6 2 1 0 2 2 2 0 NB-ARC domain DLIC PF05783.11 ABX12191.1 - 0.14 11.0 0.9 0.93 8.2 0.1 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) His_Phos_1 PF00300.22 ABX12191.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) AAA_23 PF13476.6 ABX12191.1 - 0.14 12.6 4.0 13 6.2 0.0 3.2 2 1 0 3 3 3 0 AAA domain AAA PF00004.29 ABX12191.1 - 0.16 12.4 0.3 4.2 7.8 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Fer4_17 PF13534.6 ABX12191.1 - 2.3 8.8 9.0 0.33 11.5 1.3 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 ABX12191.1 - 2.8 8.4 8.1 13 6.3 8.6 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 ABX12191.1 - 9.4 7.1 10.9 1.1 10.0 4.3 2.7 1 1 0 1 1 1 0 4Fe-4S single cluster domain Peptidase_M17 PF00883.21 ABX12192.1 - 2.2e-121 405.0 0.1 2.9e-121 404.6 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 ABX12192.1 - 6.4e-19 68.1 0.3 1.8e-18 66.6 0.3 1.8 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain VAPB_antitox PF02697.14 ABX12193.1 - 0.014 16.2 0.3 0.034 14.9 0.3 1.7 1 1 0 1 1 1 0 Putative antitoxin T4_baseplate PF12322.8 ABX12194.1 - 0.0054 16.2 1.1 0.64 9.5 0.1 2.1 2 0 0 2 2 2 2 T4 bacteriophage base plate protein Zn_ribbon_SprT PF17283.2 ABX12194.1 - 0.0083 16.0 12.8 0.22 11.5 2.1 2.4 2 0 0 2 2 2 2 SprT-like zinc ribbon domain zinc_ribbon_6 PF14599.6 ABX12194.1 - 0.011 15.7 12.0 0.56 10.3 2.4 2.7 2 2 0 2 2 2 0 Zinc-ribbon DNA_RNApol_7kD PF03604.13 ABX12194.1 - 0.092 12.4 19.1 1.5 8.6 5.6 2.9 2 2 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit C1_1 PF00130.22 ABX12194.1 - 0.11 12.4 11.5 1.5 8.8 1.7 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Molybdop_Fe4S4 PF04879.16 ABX12194.1 - 0.18 11.8 8.8 1.6 8.7 0.8 2.2 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain DUF1059 PF06348.11 ABX12194.1 - 0.18 12.1 3.3 10 6.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) SCIFF PF13165.6 ABX12194.1 - 0.91 9.5 13.4 1.3 9.0 0.5 3.3 4 0 0 4 4 4 0 Six-cysteine peptide SCIFF CpXC PF14353.6 ABX12194.1 - 2.4 8.2 7.0 9 6.4 0.3 2.3 2 0 0 2 2 2 0 CpXC protein Elf1 PF05129.13 ABX12194.1 - 2.5 8.2 11.6 2 8.5 0.8 2.8 2 2 1 3 3 3 0 Transcription elongation factor Elf1 like LIM PF00412.22 ABX12194.1 - 3.1 8.1 12.1 7.3 6.9 2.2 2.4 2 0 0 2 2 2 0 LIM domain Ribul_P_3_epim PF00834.19 ABX12195.1 - 1e-50 171.9 0.2 1.4e-50 171.4 0.2 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Transketolase_N PF00456.21 ABX12195.1 - 4.9e-49 167.1 0.4 8e-48 163.1 0.4 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 ABX12195.1 - 1.4e-06 27.8 0.0 1.4e-05 24.5 0.0 2.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 ABX12195.1 - 1.9e-05 23.8 0.0 3.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 ABX12195.1 - 6.6e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 ABX12195.1 - 0.0015 17.4 0.9 0.0035 16.2 0.1 1.9 2 0 0 2 2 2 1 XFP N-terminal domain Transketolase_C PF02780.20 ABX12196.1 - 7.2e-32 109.9 0.0 1.3e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 ABX12196.1 - 2.1e-29 102.4 0.0 3.5e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 ABX12196.1 - 0.0053 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II TAL_FSA PF00923.19 ABX12197.1 - 3e-63 213.9 0.0 7.8e-63 212.5 0.0 1.6 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase FMN_dh PF01070.18 ABX12197.1 - 0.2 10.6 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase CorA PF01544.18 ABX12199.1 - 7.4e-76 255.2 3.2 8.7e-76 255.0 3.2 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Prominin PF05478.11 ABX12199.1 - 0.012 13.6 0.7 0.022 12.7 0.7 1.4 1 0 0 1 1 1 0 Prominin Focal_AT PF03623.13 ABX12199.1 - 0.041 13.9 0.5 0.1 12.6 0.5 1.7 1 0 0 1 1 1 0 Focal adhesion targeting region HMMR_N PF15905.5 ABX12199.1 - 0.29 10.6 2.6 0.49 9.8 2.6 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF5082 PF16888.5 ABX12199.1 - 1.3 9.3 7.0 25 5.2 1.1 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) T3SchapCesA PF11439.8 ABX12199.1 - 2.4 8.4 7.2 1.9 8.7 0.4 3.0 2 1 1 3 3 3 0 Type III secretion system filament chaperone CesA DUF5611 PF18446.1 ABX12200.1 - 0.081 13.8 0.3 0.13 13.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5611) DOT1 PF08123.13 ABX12202.1 - 0.00027 20.5 1.4 0.015 14.8 0.5 2.6 2 2 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 ABX12202.1 - 0.00031 20.6 0.2 0.00049 19.9 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX12202.1 - 0.0026 18.4 0.0 0.0052 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain HdeA PF06411.11 ABX12202.1 - 0.021 15.0 0.7 0.078 13.2 0.1 2.1 2 0 0 2 2 2 0 HdeA/HdeB family CUB PF00431.20 ABX12202.1 - 0.023 15.1 0.5 3.3 8.1 0.0 2.2 2 0 0 2 2 2 0 CUB domain Methyltransf_18 PF12847.7 ABX12202.1 - 0.03 14.2 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ABX12202.1 - 0.054 14.1 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPF0147 PF03685.13 ABX12203.1 - 2.4e-31 107.6 1.3 2.8e-31 107.4 1.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) PPDK_N PF01326.19 ABX12203.1 - 0.01 15.1 0.2 0.012 14.9 0.2 1.3 1 1 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Ribosomal_L5 PF00281.19 ABX12203.1 - 0.079 13.3 0.7 0.13 12.6 0.4 1.5 2 0 0 2 2 2 0 Ribosomal protein L5 UPF0253 PF06786.12 ABX12203.1 - 0.093 13.0 0.0 16 5.8 0.0 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0253) UvrB PF12344.8 ABX12203.1 - 0.11 12.4 1.8 4.9 7.1 0.2 2.3 2 0 0 2 2 2 0 Ultra-violet resistance protein B Rieske PF00355.26 ABX12204.1 - 1.2e-18 66.8 0.0 1.5e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ABX12204.1 - 4.4e-08 33.0 0.0 5.2e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF3238 PF11579.8 ABX12204.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3238) Acetyltransf_1 PF00583.25 ABX12205.1 - 4.4e-06 26.9 0.0 8.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ABX12205.1 - 0.0089 16.4 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABX12205.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAA_hydrolase PF01557.18 ABX12206.1 - 4.9e-70 235.6 0.0 6.2e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 ABX12206.1 - 0.0023 18.8 0.0 0.008 17.0 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2437) tRNA-synt_1c PF00749.21 ABX12207.1 - 1.5e-82 277.0 0.0 3.2e-82 275.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 ABX12207.1 - 7.8e-26 91.0 2.2 8.2e-26 90.9 0.1 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF5105 PF17118.5 ABX12207.1 - 0.071 12.9 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) polyprenyl_synt PF00348.17 ABX12208.1 - 1.8e-68 230.4 0.0 2.2e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 ABX12208.1 - 0.044 13.1 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain NUDIX PF00293.28 ABX12209.1 - 1.7e-13 50.7 0.1 2.5e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain AA_kinase PF00696.28 ABX12210.1 - 1.1e-30 107.0 0.0 1.3e-30 106.8 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family DUF1967 PF09269.11 ABX12210.1 - 0.12 12.4 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) GHMP_kinases_N PF00288.26 ABX12211.1 - 8.2e-18 64.4 0.3 2.8e-17 62.7 0.2 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ABX12211.1 - 4.8e-12 46.1 0.1 9.6e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 ABX12211.1 - 0.00045 19.7 0.0 0.00083 18.9 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature DUF695 PF05117.12 ABX12211.1 - 0.037 14.2 0.6 6.2 7.0 0.0 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF695) TANGO2 PF05742.12 ABX12211.1 - 0.092 12.8 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Transport and Golgi organisation 2 Ribosomal_S2 PF00318.20 ABX12212.1 - 1.5e-21 76.7 0.2 8.3e-12 44.8 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein S2 AP_endonuc_2 PF01261.24 ABX12212.1 - 0.029 13.8 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel RhaT PF06379.12 ABX12212.1 - 0.23 10.7 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 L-rhamnose-proton symport protein (RhaT) Enolase_C PF00113.22 ABX12213.1 - 9.7e-59 199.0 0.1 1.4e-58 198.5 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ABX12213.1 - 3.3e-21 75.8 0.0 9.6e-21 74.3 0.0 1.8 1 1 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ABX12213.1 - 5.1e-06 26.2 0.0 3.5e-05 23.5 0.0 2.1 1 1 1 2 2 2 1 Enolase C-terminal domain-like RNA_pol_N PF01194.17 ABX12214.1 - 5.3e-28 97.1 0.4 7.1e-28 96.7 0.4 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Translin PF01997.16 ABX12215.1 - 2.7e-10 40.6 3.5 1.7e-08 34.7 3.5 2.3 1 1 0 1 1 1 1 Translin family BAR_3 PF16746.5 ABX12215.1 - 0.028 14.1 1.3 0.29 10.8 0.3 2.2 2 0 0 2 2 2 0 BAR domain of APPL family CRISPR_Cas2 PF09827.9 ABX12215.1 - 0.26 11.5 2.7 7 6.9 0.1 3.0 2 1 1 3 3 3 0 CRISPR associated protein Cas2 YjeF_N PF03853.15 ABX12216.1 - 7.2e-47 159.4 0.0 8.4e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Lactamase_B PF00753.27 ABX12217.1 - 3.5e-20 72.9 1.5 4.4e-18 66.0 1.5 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ABX12217.1 - 1.5e-05 24.6 0.1 2.5e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DBI_PRT PF02277.17 ABX12218.1 - 2e-09 37.1 0.1 2.7e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyltransferase SIS PF01380.22 ABX12219.1 - 1.6e-48 163.9 3.1 2.1e-25 89.1 1.9 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ABX12219.1 - 3.5e-20 72.6 0.0 6e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ABX12219.1 - 4.5e-16 58.9 0.1 3.3e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain SIS_2 PF13580.6 ABX12219.1 - 1.7e-06 28.1 2.2 0.00022 21.2 0.5 3.2 2 1 1 3 3 3 1 SIS domain GATase_4 PF13230.6 ABX12219.1 - 3e-05 23.1 0.1 5.3e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II S4 PF01479.25 ABX12220.1 - 5.3e-11 42.1 0.1 4.7e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 S4 domain Ribosomal_S13 PF00416.22 ABX12221.1 - 2.1e-40 138.1 0.1 2.4e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.6 ABX12221.1 - 0.097 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif HTH_20 PF12840.7 ABX12222.1 - 2.1e-05 24.5 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4423 PF14394.6 ABX12222.1 - 0.00023 20.9 0.1 0.00037 20.2 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_AsnC-type PF13404.6 ABX12222.1 - 0.0015 18.3 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_45 PF14947.6 ABX12222.1 - 0.0017 18.3 0.0 0.0024 17.8 0.0 1.3 1 1 0 1 1 1 1 Winged helix-turn-helix HTH_5 PF01022.20 ABX12222.1 - 0.0037 17.1 0.2 0.0059 16.5 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_9 PF08221.11 ABX12222.1 - 0.0085 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_24 PF13412.6 ABX12222.1 - 0.087 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cullin_Nedd8 PF10557.9 ABX12222.1 - 0.096 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Cullin protein neddylation domain TrmB PF01978.19 ABX12222.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB EMP24_GP25L PF01105.24 ABX12223.1 - 0.0013 18.7 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3098 PF11297.8 ABX12223.1 - 1 9.0 4.4 1.2 8.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) ZnuA PF01297.17 ABX12224.1 - 2.1e-73 246.9 0.2 2.7e-73 246.5 0.2 1.1 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic Spheroidin PF05541.12 ABX12224.1 - 0.035 12.0 0.1 0.045 11.6 0.1 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein ABC_tran PF00005.27 ABX12225.1 - 7.5e-32 110.7 0.0 1.4e-31 109.8 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 ABX12225.1 - 2.9e-08 33.9 0.5 0.00048 20.0 0.3 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABX12225.1 - 7.2e-07 28.9 1.1 6.6e-05 22.5 1.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABX12225.1 - 7.5e-06 26.6 0.0 4.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ABX12225.1 - 4.7e-05 23.3 0.1 0.00018 21.4 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ABX12225.1 - 0.0001 22.0 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 ABX12225.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ABX12225.1 - 0.0013 18.3 0.1 0.0045 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ABX12225.1 - 0.002 18.2 0.4 0.0042 17.1 0.4 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 ABX12225.1 - 0.0064 16.4 0.2 1.8 8.5 0.1 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ABX12225.1 - 0.0065 16.7 0.1 0.018 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ABX12225.1 - 0.0078 16.6 0.3 0.023 15.1 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ABX12225.1 - 0.011 16.3 0.1 0.16 12.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABX12225.1 - 0.03 14.0 0.3 0.061 13.0 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ABX12225.1 - 0.031 14.7 0.7 0.11 12.9 0.7 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 ABX12225.1 - 0.037 14.3 0.4 0.72 10.1 0.1 2.5 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 ABX12225.1 - 0.037 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 ABX12225.1 - 0.038 14.2 0.1 0.069 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 ABX12225.1 - 0.038 13.8 0.5 0.78 9.5 0.2 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_ATPase PF09818.9 ABX12225.1 - 0.055 12.3 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 ABX12225.1 - 0.078 12.1 0.1 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 ABX12225.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 ABX12225.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.23 ABX12225.1 - 0.16 12.0 0.2 0.39 10.8 0.2 1.6 1 0 0 1 1 1 0 Dynamin family AAA_28 PF13521.6 ABX12225.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ABX12225.1 - 0.17 11.5 0.7 0.41 10.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain ABC-3 PF00950.17 ABX12226.1 - 6.1e-67 225.8 32.6 7e-67 225.6 32.6 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 ABX12226.1 - 0.0013 17.9 36.9 0.0019 17.3 36.6 1.4 1 1 0 1 1 1 1 FecCD transport family UPF0182 PF03699.13 ABX12226.1 - 0.69 8.0 4.3 1.1 7.3 4.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) ABC-3 PF00950.17 ABX12227.1 - 6e-44 150.5 40.4 1.9e-43 148.9 40.4 1.7 1 1 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 ABX12227.1 - 0.0011 18.0 37.3 0.0031 16.6 37.3 1.8 1 1 0 1 1 1 1 FecCD transport family ZT_dimer PF16916.5 ABX12228.1 - 2.6e-49 165.2 17.1 1.4e-19 70.0 2.8 3.2 3 0 0 3 3 3 3 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 ABX12228.1 - 5.3e-43 147.1 15.9 6.7e-43 146.8 15.9 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1206 PF06724.11 ABX12228.1 - 0.048 13.7 1.3 0.23 11.6 0.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) Fe_dep_repr_C PF02742.15 ABX12228.1 - 0.66 10.1 4.1 1.5 8.9 0.5 3.1 4 0 0 4 4 4 0 Iron dependent repressor, metal binding and dimerisation domain ATP-synt_I PF03899.15 ABX12228.1 - 2.1 8.8 9.3 1.2 9.6 0.6 2.7 3 0 0 3 3 3 0 ATP synthase I chain RRM_occluded PF16842.5 ABX12228.1 - 3.2 7.7 6.1 0.32 10.9 0.3 2.4 3 0 0 3 3 3 0 Occluded RNA-recognition motif MG2 PF01835.19 ABX12229.1 - 0.00025 21.4 0.0 0.0013 19.1 0.0 2.3 1 0 0 1 1 1 1 MG2 domain DEC-1_N PF04625.13 ABX12230.1 - 8.2 5.3 7.4 13 4.6 7.4 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Radical_SAM PF04055.21 ABX12232.1 - 1.6e-12 48.1 0.0 2.9e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 ABX12232.1 - 0.07 13.2 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain AIRC PF00731.20 ABX12233.1 - 4e-16 58.9 1.4 1.9e-15 56.8 2.2 1.6 2 0 0 2 2 2 1 AIR carboxylase NAD_kinase PF01513.21 ABX12233.1 - 0.00065 19.0 0.0 0.001 18.3 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase PrpR_N PF06506.11 ABX12233.1 - 0.0048 16.5 0.6 0.29 10.7 0.2 2.5 2 0 0 2 2 2 1 Propionate catabolism activator DUF3969 PF13108.6 ABX12233.1 - 0.0071 16.3 0.2 0.015 15.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3969) Hpr_kinase_N PF02603.16 ABX12233.1 - 0.15 12.1 0.9 6.4 6.8 0.2 2.3 2 0 0 2 2 2 0 HPr Serine kinase N terminus HTH_ParB PF17762.1 ABX12233.1 - 0.18 11.7 0.8 0.38 10.6 0.1 2.0 2 0 0 2 2 2 0 HTH domain found in ParB protein Ldh_1_N PF00056.23 ABX12234.1 - 1.4e-36 125.7 0.5 3.1e-36 124.6 0.5 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ABX12234.1 - 1.1e-28 100.2 0.0 1.9e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4C PF11975.8 ABX12234.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain DUF111 PF01969.17 ABX12235.1 - 6.7e-108 361.1 0.0 7.6e-108 360.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 RSS_P20 PF11757.8 ABX12235.1 - 3.3 8.2 9.9 21 5.6 0.5 3.8 3 1 1 4 4 4 0 Suppressor of RNA silencing P21-like N-terminal domain QueC PF06508.13 ABX12236.1 - 3.9e-09 36.3 0.1 3.6e-07 29.9 0.1 2.4 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ABX12236.1 - 1.4e-07 30.6 0.0 4.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 tRNA methyl transferase ATP_bind_3 PF01171.20 ABX12236.1 - 1.8e-07 31.1 0.1 3.2e-06 27.0 0.1 2.4 1 1 1 2 2 2 1 PP-loop family NAD_synthase PF02540.17 ABX12236.1 - 5.5e-07 28.9 0.0 1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 ABX12236.1 - 3e-06 27.2 0.1 6.8e-06 26.0 0.1 1.6 2 1 0 2 2 2 1 Asparagine synthase ThiI PF02568.14 ABX12236.1 - 0.00016 21.3 0.0 0.00041 20.0 0.0 1.8 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PriCT_1 PF08708.11 ABX12236.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Aminotran_5 PF00266.19 ABX12237.1 - 4.8e-86 289.0 0.5 5.9e-86 288.7 0.5 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ABX12237.1 - 1.6e-05 24.4 0.1 1.9e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 ABX12237.1 - 1.6e-05 23.6 0.0 2.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ABX12237.1 - 0.00022 20.6 0.3 0.00063 19.2 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 ABX12237.1 - 0.0021 16.8 0.0 0.0035 16.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_3 PF00202.21 ABX12237.1 - 0.043 12.5 0.0 1 7.9 0.0 2.3 2 0 0 2 2 2 0 Aminotransferase class-III DUF5011 PF16403.5 ABX12238.1 - 0.11 12.6 7.5 2.4 8.3 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) MG2 PF01835.19 ABX12239.1 - 0.015 15.8 0.3 0.041 14.3 0.1 1.8 2 0 0 2 2 2 0 MG2 domain Big_1 PF02369.16 ABX12239.1 - 3.9 7.5 13.2 1.2 9.2 3.7 3.3 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 1) Big_3_5 PF16640.5 ABX12239.1 - 7 6.9 17.3 1.9 8.7 3.1 3.3 2 1 0 3 3 3 0 Bacterial Ig-like domain (group 3) Cadherin-like PF12733.7 ABX12240.1 - 7.2 7.2 8.0 4 8.0 0.2 2.9 2 1 0 2 2 2 0 Cadherin-like beta sandwich domain MG2 PF01835.19 ABX12241.1 - 0.0062 17.0 0.1 0.013 16.0 0.1 1.5 1 0 0 1 1 1 1 MG2 domain RNA_pol_Rpb5_C PF01191.19 ABX12242.1 - 2.9e-26 91.1 0.0 3.4e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb2_6 PF00562.28 ABX12243.1 - 2.9e-125 418.4 0.0 4.1e-125 417.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ABX12243.1 - 3.6e-48 163.8 0.0 5.5e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 ABX12243.1 - 3.4e-32 110.7 0.1 7.5e-32 109.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 ABX12243.1 - 1.2e-27 95.9 0.1 2.9e-27 94.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 ABX12243.1 - 1.8e-24 86.4 0.0 4.5e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 ABX12243.1 - 4.5e-19 68.5 0.3 1e-18 67.3 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 ABX12243.1 - 1.8e-08 34.8 0.0 4.7e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 FYVE_2 PF02318.16 ABX12243.1 - 0.1 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.11 ABX12243.1 - 0.2 11.6 1.9 0.59 10.1 1.5 2.0 2 0 0 2 2 1 0 Putative transposase DNA-binding domain RecR PF02132.15 ABX12243.1 - 0.24 11.0 1.8 1.9 8.1 0.6 2.4 2 0 0 2 2 2 0 RecR protein Ribosomal_L37e PF01907.19 ABX12243.1 - 0.36 11.0 0.9 0.83 9.9 0.9 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e RNA_pol_Rpb1_1 PF04997.12 ABX12244.1 - 2.2e-92 309.7 0.0 6.5e-92 308.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ABX12244.1 - 5.7e-84 281.7 1.9 1.3e-83 280.5 1.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ABX12244.1 - 9.6e-73 243.9 0.0 1.7e-72 243.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ABX12244.1 - 9.4e-34 116.6 0.3 4.2e-33 114.5 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ABX12244.1 - 5.3e-24 84.2 0.0 1e-22 80.1 0.0 2.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 LSM PF01423.22 ABX12245.1 - 1.4e-18 66.3 0.4 1.6e-18 66.1 0.4 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ABX12245.1 - 0.022 14.9 0.0 0.024 14.8 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain TPR_2 PF07719.17 ABX12247.1 - 6.6e-12 44.6 0.1 0.0054 16.8 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 ABX12247.1 - 1.9e-11 43.2 0.6 0.0013 18.5 1.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ABX12247.1 - 1.5e-08 34.1 0.2 0.0031 17.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ABX12247.1 - 4.7e-08 32.9 4.7 0.0038 17.5 1.6 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 ABX12247.1 - 8.5e-08 32.6 0.4 2.8e-06 27.7 1.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ABX12247.1 - 1e-06 28.9 0.1 0.028 14.7 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 ABX12247.1 - 5.1e-06 26.9 0.0 0.15 13.0 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ABX12247.1 - 5.2e-05 23.8 0.0 0.00023 21.7 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 ABX12247.1 - 0.00014 21.4 4.3 0.38 10.5 1.8 3.5 2 1 1 3 3 3 2 TPR repeat NARP1 PF12569.8 ABX12247.1 - 0.0018 17.3 13.3 0.31 9.9 0.0 3.2 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 DUF966 PF06136.13 ABX12247.1 - 0.0051 16.6 13.5 0.0051 16.6 13.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF966) TPR_7 PF13176.6 ABX12247.1 - 0.04 14.0 0.0 11 6.3 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 ABX12247.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_10 PF13374.6 ABX12247.1 - 0.16 11.9 1.0 3.2 7.8 1.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L7Ae PF01248.26 ABX12248.1 - 4.8e-15 55.1 0.3 5.8e-15 54.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family KH_2 PF07650.17 ABX12249.1 - 7.5e-20 70.5 0.9 5.6e-12 45.3 0.1 2.1 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 ABX12249.1 - 3.2e-12 46.2 0.7 2.9e-05 23.9 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 ABX12249.1 - 5.3e-09 36.0 3.5 1.7e-08 34.4 0.3 2.1 2 0 0 2 2 2 1 NusA-like KH domain KH_1 PF00013.29 ABX12249.1 - 0.00078 19.2 2.2 0.016 15.0 0.2 2.3 1 1 1 2 2 2 2 KH domain Ribosom_S12_S23 PF00164.25 ABX12250.1 - 5.8e-47 158.0 0.2 7.4e-47 157.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S7 PF00177.21 ABX12251.1 - 2.3e-37 127.9 0.9 3.4e-37 127.4 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CxxCxxCC PF03692.15 ABX12253.1 - 4.8e-08 33.6 0.2 1.6e-07 31.9 0.2 1.8 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Acetyltransf_1 PF00583.25 ABX12254.1 - 2.9e-16 59.8 0.0 3.4e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ABX12254.1 - 5.6e-14 52.2 0.0 7.6e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABX12254.1 - 1.6e-12 47.6 0.0 2.2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ABX12254.1 - 1e-06 29.0 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ABX12254.1 - 0.00011 22.9 0.0 0.00013 22.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ABX12254.1 - 0.00013 21.9 0.0 0.00021 21.2 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ABX12254.1 - 0.00098 19.2 0.0 0.0018 18.4 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 ABX12254.1 - 0.0017 17.8 0.3 0.0087 15.5 0.3 2.0 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_8 PF13523.6 ABX12254.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4581 PF15167.6 ABX12254.1 - 0.12 12.6 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) Trp_halogenase PF04820.14 ABX12255.1 - 3.2e-05 23.0 0.0 9.9e-05 21.4 0.0 1.6 1 1 0 1 1 1 1 Tryptophan halogenase Nitroreductase PF00881.24 ABX12256.1 - 5.3e-33 114.5 0.0 7e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABX12256.1 - 4.2e-14 52.6 0.0 4.3e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 Putative TM nitroreductase PhnH PF05845.12 ABX12256.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 1 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) zf-Sec23_Sec24 PF04810.15 ABX12258.1 - 0.012 15.7 1.5 0.021 14.8 1.5 1.5 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger zf-MYST PF17772.1 ABX12258.1 - 0.015 14.9 0.3 0.02 14.5 0.3 1.3 1 0 0 1 1 1 0 MYST family zinc finger domain zf-like PF04071.12 ABX12258.1 - 0.024 14.6 0.4 0.029 14.3 0.4 1.2 1 0 0 1 1 1 0 Cysteine-rich small domain Rtf2 PF04641.12 ABX12258.1 - 0.024 14.0 1.4 0.026 13.9 1.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger OrfB_Zn_ribbon PF07282.11 ABX12258.1 - 0.057 13.3 1.9 0.11 12.4 0.6 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-4CXXC_R1 PF10497.9 ABX12258.1 - 0.06 13.6 2.2 0.078 13.2 2.1 1.3 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PHD_2 PF13831.6 ABX12258.1 - 0.096 12.3 2.5 0.64 9.6 0.2 2.2 2 0 0 2 2 2 0 PHD-finger Apolipoprotein PF01442.18 ABX12259.1 - 0.08 12.8 20.1 0.032 14.1 5.9 3.0 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain UDG PF03167.19 ABX12262.1 - 3.7e-33 114.7 0.0 4.8e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily tRNA-synt_1 PF00133.22 ABX12263.1 - 3.3e-61 207.3 1.4 7.1e-60 202.9 1.4 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ABX12263.1 - 1.3e-22 80.4 0.9 2.7e-22 79.4 0.9 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ABX12263.1 - 2.6e-22 79.1 0.3 2.2e-11 43.1 0.1 3.1 2 1 1 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ABX12263.1 - 4.6e-11 42.6 7.3 4e-07 29.7 0.0 3.4 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 ABX12263.1 - 8e-08 32.0 0.3 2.4e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 Nse4-Nse3_bdg PF15412.6 ABX12263.1 - 0.12 12.5 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE V-SNARE PF05008.15 ABX12263.1 - 4.4 7.7 6.1 21 5.5 1.4 2.8 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus tRNA-synt_2c PF01411.19 ABX12264.1 - 7e-79 265.8 0.0 7e-79 265.8 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 ABX12264.1 - 1.9e-14 53.5 1.1 1.9e-14 53.5 1.1 2.2 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 ABX12264.1 - 1.4e-11 45.0 7.8 6.1e-11 42.9 7.8 2.2 1 1 0 1 1 1 1 DHHA1 domain YolD PF08863.10 ABX12264.1 - 0.013 15.5 0.2 0.013 15.5 0.2 2.5 2 0 0 2 2 2 0 YolD-like protein PVL_ORF50 PF07768.11 ABX12264.1 - 0.062 13.6 1.9 0.2 12.0 1.9 1.8 1 0 0 1 1 1 0 PVL ORF-50-like family ADH_N PF08240.12 ABX12265.1 - 3.9e-23 81.4 0.1 8.1e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ABX12265.1 - 1e-07 31.7 0.0 4.4e-07 29.6 0.0 2.0 2 1 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 ABX12265.1 - 2.4e-06 27.6 0.0 8.4e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 ABX12265.1 - 0.00069 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase PALP PF00291.25 ABX12265.1 - 0.002 17.6 0.0 0.0053 16.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N_2 PF13602.6 ABX12265.1 - 0.0048 17.9 0.0 0.011 16.8 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UPF0444 PF15475.6 ABX12265.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 GSDH PF07995.11 ABX12267.1 - 1.8e-88 297.0 0.2 2.5e-88 296.6 0.2 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase HATPase_c PF02518.26 ABX12268.1 - 1.8e-19 70.3 0.1 5.8e-19 68.7 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABX12268.1 - 2.7e-12 46.6 0.5 7.8e-12 45.1 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 ABX12268.1 - 3.3e-10 39.8 0.9 1.3e-09 37.9 0.1 2.3 2 0 0 2 2 2 1 GHKL domain PorA PF11271.8 ABX12268.1 - 2.9e-09 36.7 0.2 4.9e-09 35.9 0.2 1.3 1 0 0 1 1 1 1 Porin PorA HATPase_c_2 PF13581.6 ABX12268.1 - 0.002 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Baculo_PEP_C PF04513.12 ABX12268.1 - 0.028 14.5 1.1 0.054 13.5 1.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_11_kDa PF06143.11 ABX12268.1 - 0.033 13.8 2.3 0.22 11.1 0.4 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family ApoLp-III PF07464.11 ABX12268.1 - 0.044 13.9 1.1 0.11 12.6 0.4 1.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) YajC PF02699.15 ABX12268.1 - 0.16 11.9 0.2 0.16 11.9 0.2 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit DUF5345 PF17280.2 ABX12268.1 - 0.62 10.1 2.8 0.32 11.0 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Ribosomal_60s PF00428.19 ABX12270.1 - 9.5e-14 51.8 19.7 1.1e-13 51.5 19.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF5327 PF17261.2 ABX12270.1 - 0.022 15.5 0.3 0.03 15.1 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5327) UPF0126 PF03458.13 ABX12271.1 - 1.4e-38 130.7 26.2 2.1e-19 69.1 9.0 2.3 2 0 0 2 2 2 2 UPF0126 domain Response_reg PF00072.24 ABX12272.1 - 2.4e-24 85.7 0.5 2.7e-24 85.5 0.5 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Myosin-VI_CBD PF16521.5 ABX12272.1 - 0.056 13.5 0.0 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 Myosin VI cargo binding domain bZIP_1 PF00170.21 ABX12273.1 - 0.00042 20.3 3.8 0.00042 20.3 3.8 3.5 3 1 0 3 3 3 1 bZIP transcription factor kleA_kleC PF17383.2 ABX12273.1 - 0.038 14.3 8.5 0.062 13.6 0.3 3.1 4 0 0 4 4 3 0 Uncharacterized KorC regulated protein A GDE_C PF06202.14 ABX12273.1 - 0.043 12.7 1.3 0.064 12.2 1.3 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase YlqD PF11068.8 ABX12273.1 - 0.049 14.0 14.8 2.4 8.5 0.7 3.2 2 1 0 3 3 3 0 YlqD protein OmpH PF03938.14 ABX12273.1 - 0.1 12.9 25.0 0.41 11.0 15.6 3.0 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) ubiquitin PF00240.23 ABX12273.1 - 0.17 11.7 4.2 0.17 11.6 0.2 2.8 2 1 1 3 3 3 0 Ubiquitin family DUF1128 PF06569.11 ABX12273.1 - 0.17 11.9 10.9 0.075 13.0 1.9 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1128) Serine_rich PF08824.10 ABX12273.1 - 0.21 11.6 0.2 0.21 11.6 0.2 2.2 3 0 0 3 3 2 0 Serine rich protein interaction domain PilJ PF13675.6 ABX12273.1 - 0.4 10.7 3.5 8.1 6.5 0.1 3.1 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term KxDL PF10241.9 ABX12273.1 - 0.41 11.0 6.5 0.53 10.6 0.3 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF1664 PF07889.12 ABX12273.1 - 0.64 10.1 5.5 7.7 6.6 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_Mu_Gam PF07352.12 ABX12273.1 - 1.2 9.0 22.4 0.21 11.5 3.7 3.4 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Bac_DNA_binding PF00216.21 ABX12273.1 - 1.2 9.4 5.7 8.3 6.7 0.2 2.6 3 0 0 3 3 2 0 Bacterial DNA-binding protein Apolipoprotein PF01442.18 ABX12273.1 - 2.2 8.1 14.6 1 9.2 7.5 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain YabA PF06156.13 ABX12273.1 - 2.3 8.9 15.5 13 6.5 0.9 3.4 2 1 0 2 2 2 0 Initiation control protein YabA Muted PF14942.6 ABX12273.1 - 2.4 8.5 26.2 0.086 13.2 6.7 3.4 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein Nnf1 PF03980.14 ABX12273.1 - 2.5 8.5 14.9 0.11 12.9 1.5 3.3 2 1 1 3 3 3 0 Nnf1 Ax_dynein_light PF10211.9 ABX12273.1 - 2.6 8.0 21.0 1.5 8.7 1.6 3.1 3 0 0 3 3 3 0 Axonemal dynein light chain DivIC PF04977.15 ABX12273.1 - 3 7.7 16.7 0.18 11.6 2.8 3.4 3 1 0 3 3 2 0 Septum formation initiator BLOC1_2 PF10046.9 ABX12273.1 - 3.5 8.0 15.9 4.3 7.7 1.4 3.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 ABX12273.1 - 4.6 6.5 8.1 5.9 6.1 3.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Arc_PepC_II PF06847.11 ABX12273.1 - 5 7.7 14.8 0.64 10.6 0.8 3.4 2 1 1 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II TSC22 PF01166.18 ABX12273.1 - 8.7 6.8 12.0 11 6.4 6.0 3.6 2 2 1 3 3 3 0 TSC-22/dip/bun family DUF1043 PF06295.12 ABX12273.1 - 9 6.3 11.6 1.5 8.8 6.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Zn_Tnp_IS1595 PF12760.7 ABX12275.1 - 0.02 14.8 0.5 0.045 13.7 0.5 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Halogen_Hydrol PF10112.9 ABX12275.1 - 0.045 13.8 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4010 PF13194.6 ABX12275.1 - 0.087 12.5 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) TFIIS_C PF01096.18 ABX12275.1 - 0.12 12.2 1.8 5.4 7.0 0.2 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Fer4_2 PF12797.7 ABX12275.1 - 0.16 12.1 1.9 5.1 7.4 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Pam17 PF08566.10 ABX12276.1 - 2.8 7.7 4.7 2.8 7.7 0.4 2.9 2 2 0 2 2 2 0 Mitochondrial import protein Pam17 Ribosomal_L10 PF00466.20 ABX12277.1 - 2.4e-20 72.5 2.4 2.4e-20 72.5 2.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 ABX12277.1 - 3.5e-20 71.8 0.1 1.3e-19 70.0 0.1 2.0 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P HPHLAWLY PF14925.6 ABX12277.1 - 0.31 9.7 4.8 0.082 11.6 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF4411 PF14367.6 ABX12277.1 - 0.71 9.8 3.8 0.31 10.9 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) Ribosomal_L1 PF00687.21 ABX12278.1 - 1.5e-40 139.1 2.2 1.8e-40 138.9 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family AsnC_trans_reg PF01037.21 ABX12279.1 - 4.1e-15 55.5 0.0 5.7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 ABX12279.1 - 1.2e-08 34.3 0.1 2e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ABX12279.1 - 0.00028 20.7 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Ribosomal_S25 PF03297.15 ABX12279.1 - 0.0036 17.5 1.5 0.021 15.0 0.4 2.1 2 0 0 2 2 2 1 S25 ribosomal protein MarR PF01047.22 ABX12279.1 - 0.0042 17.0 0.1 0.0078 16.1 0.1 1.5 1 0 0 1 1 1 1 MarR family B-block_TFIIIC PF04182.12 ABX12279.1 - 0.0053 16.9 0.1 0.0077 16.4 0.1 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 ABX12279.1 - 0.006 16.4 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 ABX12279.1 - 0.022 14.7 0.1 0.091 12.7 0.1 2.0 2 0 0 2 2 2 0 HTH domain CNDH2_N PF06278.11 ABX12279.1 - 0.074 13.3 0.5 0.26 11.5 0.1 1.9 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Cactin_mid PF10312.9 ABX12280.1 - 0.059 13.1 0.1 0.062 13.0 0.1 1.0 1 0 0 1 1 1 0 Conserved mid region of cactin Ribosomal_L11_N PF03946.14 ABX12281.1 - 7.1e-22 77.0 0.6 1.4e-21 76.0 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ABX12281.1 - 6.9e-18 64.9 1.3 1e-17 64.3 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Spt5-NGN PF03439.13 ABX12282.1 - 9.9e-21 73.4 0.0 1.8e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 ABX12282.1 - 1.3e-06 28.2 0.1 2.5e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 KOW motif tRNA_deacylase PF04414.12 ABX12283.1 - 5e-64 215.6 0.0 6.1e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase DNA_binding_1 PF01035.20 ABX12284.1 - 3.9e-28 97.4 0.1 4.6e-28 97.2 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain IceA2 PF05862.11 ABX12284.1 - 0.076 13.0 0.8 8 6.5 0.1 2.5 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein Glyoxalase PF00903.25 ABX12285.1 - 9.4e-16 58.2 0.0 1.1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ABX12285.1 - 4e-09 36.7 0.0 3.6e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABX12285.1 - 5e-06 27.3 0.0 5.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 ABX12285.1 - 0.00014 21.8 0.0 0.00022 21.1 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ABX12285.1 - 0.0036 17.4 0.0 0.078 13.1 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase-like domain KDGP_aldolase PF07071.11 ABX12285.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 KDGP aldolase Med18 PF09637.10 ABX12285.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Med18 protein Ribosomal_L19e PF01280.20 ABX12286.1 - 7.3e-40 136.4 8.9 8.4e-40 136.2 8.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e Ribosomal_L32e PF01655.18 ABX12287.1 - 4e-33 114.1 0.0 5e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 PEPCK_ATP PF01293.20 ABX12288.1 - 6.2e-211 701.0 0.0 7e-211 700.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Peptidase_S8 PF00082.22 ABX12289.1 - 3.2e-55 187.5 0.2 4.9e-55 186.9 0.2 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 ABX12289.1 - 2.4e-11 43.5 0.0 8.8e-11 41.7 0.0 2.0 1 0 0 1 1 1 1 PA domain Sod_Fe_C PF02777.18 ABX12290.1 - 3.7e-39 133.0 0.0 6.2e-39 132.3 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ABX12290.1 - 2.6e-29 101.5 0.5 2.6e-29 101.5 0.5 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Prefoldin PF02996.17 ABX12291.1 - 1.5e-17 63.6 5.3 1.5e-16 60.4 5.3 2.1 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 ABX12291.1 - 4.5e-05 23.3 4.1 0.00065 19.6 0.3 2.2 2 0 0 2 2 2 1 Prefoldin subunit DUF948 PF06103.11 ABX12291.1 - 0.0075 16.5 0.9 0.051 13.8 0.1 2.1 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Pex19 PF04614.12 ABX12291.1 - 0.0089 15.8 2.5 0.0089 15.8 2.5 2.1 1 1 1 2 2 2 1 Pex19 protein family TMF_TATA_bd PF12325.8 ABX12291.1 - 0.017 15.4 3.7 0.54 10.5 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SKA2 PF16740.5 ABX12291.1 - 0.021 14.6 1.3 0.021 14.6 1.3 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 SF-assemblin PF06705.11 ABX12291.1 - 0.029 13.7 0.8 0.037 13.4 0.2 1.5 2 0 0 2 2 2 0 SF-assemblin/beta giardin HK_sensor PF16750.5 ABX12291.1 - 0.1 12.9 0.1 0.1 12.9 0.1 1.8 2 0 0 2 2 2 0 Sensor domain of 2-component histidine kinase DSPc PF00782.20 ABX12291.1 - 0.12 12.2 1.1 0.71 9.7 0.1 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain OmpH PF03938.14 ABX12291.1 - 0.14 12.5 11.8 0.21 11.9 2.8 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AIP3 PF03915.13 ABX12291.1 - 0.48 9.5 4.4 0.13 11.3 0.6 1.7 2 0 0 2 2 2 0 Actin interacting protein 3 ABC_tran_CTD PF16326.5 ABX12291.1 - 0.65 10.3 11.3 0.37 11.1 5.1 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain Mod_r PF07200.13 ABX12291.1 - 1.3 9.2 8.6 1.7 8.7 1.8 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein YjfB_motility PF14070.6 ABX12291.1 - 2.4 8.4 11.1 2 8.6 1.4 2.4 2 0 0 2 2 2 0 Putative motility protein SRP54 PF00448.22 ABX12292.1 - 3e-70 235.9 0.6 4.1e-70 235.4 0.6 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 ABX12292.1 - 4.6e-12 46.0 5.8 4.6e-12 46.0 5.8 1.9 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 ABX12292.1 - 1.8e-07 31.1 0.1 3e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ABX12292.1 - 4.9e-06 26.0 0.1 7.7e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 ABX12292.1 - 7.3e-05 23.2 1.8 0.00013 22.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ABX12292.1 - 0.00024 21.4 0.0 0.00051 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain KdpD PF02702.17 ABX12292.1 - 0.00059 19.4 1.2 0.00077 19.0 0.1 1.7 2 0 0 2 2 2 1 Osmosensitive K+ channel His kinase sensor domain AAA PF00004.29 ABX12292.1 - 0.00096 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 ABX12292.1 - 0.0013 18.1 0.2 0.002 17.5 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 ABX12292.1 - 0.0015 18.5 0.8 0.22 11.4 0.8 2.3 1 1 0 1 1 1 1 NTPase PIF1 PF05970.14 ABX12292.1 - 0.0015 17.8 0.1 0.0023 17.2 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase cobW PF02492.19 ABX12292.1 - 0.0032 17.1 0.9 0.02 14.5 0.9 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 ABX12292.1 - 0.0037 17.0 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 ABX12292.1 - 0.0038 16.9 0.1 0.015 15.0 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_19 PF13245.6 ABX12292.1 - 0.0043 17.4 0.1 0.0072 16.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ABX12292.1 - 0.0045 17.0 1.6 0.011 15.8 0.4 2.2 2 1 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 ABX12292.1 - 0.0062 16.9 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 ABX12292.1 - 0.0064 16.4 0.1 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase SPOUT_MTase PF02590.17 ABX12292.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase KTI12 PF08433.10 ABX12292.1 - 0.012 15.1 0.7 0.027 13.9 0.0 1.8 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 ABX12292.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ABX12292.1 - 0.021 15.3 0.0 0.043 14.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 ABX12292.1 - 0.036 14.3 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ABX12292.1 - 0.037 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain TK PF00265.18 ABX12292.1 - 0.041 13.8 0.1 0.073 12.9 0.1 1.3 1 0 0 1 1 1 0 Thymidine kinase AAA_7 PF12775.7 ABX12292.1 - 0.059 12.9 0.4 0.11 11.9 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region PBP1_TM PF14812.6 ABX12292.1 - 0.077 13.4 8.8 0.15 12.4 8.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MeaB PF03308.16 ABX12292.1 - 0.095 11.7 0.1 0.3 10.0 0.1 1.7 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 ABX12292.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TPP_enzyme_M PF00205.22 ABX12292.1 - 0.12 12.1 0.2 1.1 9.0 0.1 2.6 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain Helicase_RecD PF05127.14 ABX12292.1 - 0.16 11.8 0.5 0.33 10.8 0.5 1.5 1 1 0 1 1 1 0 Helicase CLP1_P PF16575.5 ABX12292.1 - 0.18 11.6 0.2 0.4 10.5 0.0 1.6 2 0 0 2 2 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NACHT PF05729.12 ABX12292.1 - 0.19 11.6 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 ABX12292.1 - 0.85 9.7 3.3 0.57 10.3 0.6 2.2 2 1 0 2 2 1 0 50S ribosome-binding GTPase DUF4611 PF15387.6 ABX12292.1 - 2.2 8.6 11.7 20 5.5 9.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 ABX12292.1 - 5.4 7.5 13.1 12 6.4 13.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Trypan_PARP PF05887.11 ABX12292.1 - 6.5 6.7 150.0 2.5e+02 1.6 22.1 4.1 1 1 2 3 3 1 0 Procyclic acidic repetitive protein (PARP) OTCace PF00185.24 ABX12293.1 - 4.8e-53 179.4 0.1 7.4e-53 178.8 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 ABX12293.1 - 2.7e-50 170.2 0.0 4e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain F420_oxidored PF03807.17 ABX12293.1 - 0.1 13.2 0.1 1.9 9.2 0.0 2.3 1 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_L5e PF17144.4 ABX12294.1 - 2.8e-16 59.9 1.8 7.1e-13 48.9 0.8 2.6 1 1 1 2 2 2 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18p PF00861.22 ABX12294.1 - 0.0052 17.2 0.2 0.0074 16.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_S5 PF00333.20 ABX12295.1 - 8.3e-22 77.0 0.9 1.5e-21 76.2 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ABX12295.1 - 5.3e-16 57.8 0.1 9e-16 57.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_L30 PF00327.20 ABX12296.1 - 1.6e-11 43.9 0.0 3.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L27A PF00828.19 ABX12297.1 - 4.1e-14 53.4 0.4 7.5e-14 52.5 0.4 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SecY PF00344.20 ABX12298.1 - 4.3e-62 210.1 16.9 5.4e-62 209.8 16.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 ABX12298.1 - 1.4e-11 44.1 2.4 2.8e-11 43.1 0.5 2.6 2 0 0 2 2 2 1 Plug domain of Sec61p Phage_holin_5_1 PF06946.11 ABX12298.1 - 0.037 14.4 0.9 0.24 11.8 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 AAA_17 PF13207.6 ABX12299.1 - 4e-35 121.2 0.0 5.1e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ABX12299.1 - 4.8e-09 36.8 0.0 7.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 ABX12299.1 - 3.2e-07 30.2 0.1 5.2e-07 29.5 0.1 1.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 ABX12299.1 - 2.9e-06 27.6 0.0 5.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ABX12299.1 - 2.4e-05 24.3 1.5 0.0004 20.3 0.2 2.1 1 1 1 2 2 2 1 NTPase KTI12 PF08433.10 ABX12299.1 - 4.7e-05 23.0 0.1 5.9e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Roc PF08477.13 ABX12299.1 - 0.00016 21.9 0.1 0.00025 21.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ABX12299.1 - 0.00039 20.5 0.1 0.00073 19.6 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 ABX12299.1 - 0.00052 20.0 0.0 0.00067 19.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain MobB PF03205.14 ABX12299.1 - 0.00054 19.9 0.3 0.001 19.0 0.2 1.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 ABX12299.1 - 0.00064 19.5 0.1 0.001 18.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 ABX12299.1 - 0.00095 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 ABX12299.1 - 0.00099 19.5 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ABX12299.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ABX12299.1 - 0.0012 19.1 0.0 0.0016 18.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ABX12299.1 - 0.0013 18.0 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 ABX12299.1 - 0.0016 18.8 0.2 0.0028 18.0 0.2 1.6 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 ABX12299.1 - 0.0028 16.7 0.1 0.0043 16.1 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 ABX12299.1 - 0.0029 17.7 0.2 0.0061 16.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABX12299.1 - 0.0036 17.6 0.1 0.0066 16.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ABX12299.1 - 0.0039 17.1 0.1 0.0065 16.4 0.1 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 ABX12299.1 - 0.0041 17.6 1.0 0.0051 17.3 0.8 1.5 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ABX12299.1 - 0.0056 16.6 0.2 0.011 15.7 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase ATP_bind_1 PF03029.17 ABX12299.1 - 0.0068 16.2 0.2 0.017 14.9 0.1 1.7 2 0 0 2 2 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 ABX12299.1 - 0.0083 16.5 0.1 0.015 15.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 ABX12299.1 - 0.0086 15.4 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain CLP1_P PF16575.5 ABX12299.1 - 0.011 15.5 0.0 0.05 13.4 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TrwB_AAD_bind PF10412.9 ABX12299.1 - 0.011 14.7 0.2 0.019 13.9 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.18 ABX12299.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 ABX12299.1 - 0.017 14.7 0.5 0.15 11.6 0.1 2.1 1 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 ABX12299.1 - 0.02 14.1 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.22 ABX12299.1 - 0.036 14.5 0.0 0.095 13.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Guanylate_kin PF00625.21 ABX12299.1 - 0.038 13.7 0.1 0.077 12.7 0.1 1.5 1 0 0 1 1 1 0 Guanylate kinase DUF2075 PF09848.9 ABX12299.1 - 0.04 13.2 0.2 0.048 12.9 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 ABX12299.1 - 0.042 13.1 0.2 0.095 12.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin 6PF2K PF01591.18 ABX12299.1 - 0.046 13.0 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Ras PF00071.22 ABX12299.1 - 0.051 13.2 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Ras family AAA_7 PF12775.7 ABX12299.1 - 0.059 12.9 0.1 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 ABX12299.1 - 0.066 13.0 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 ABX12299.1 - 0.075 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 ABX12299.1 - 0.079 12.5 0.1 0.21 11.1 0.0 1.7 2 0 0 2 2 1 0 Ferrous iron transport protein B Thymidylate_kin PF02223.17 ABX12299.1 - 0.081 12.6 0.7 0.84 9.3 0.7 2.5 1 1 0 1 1 1 0 Thymidylate kinase T2SSE PF00437.20 ABX12299.1 - 0.082 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 ABX12299.1 - 0.087 12.6 0.1 0.21 11.4 0.0 1.6 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain Arf PF00025.21 ABX12299.1 - 0.089 12.2 0.4 0.16 11.4 0.2 1.7 2 1 0 2 2 1 0 ADP-ribosylation factor family TsaE PF02367.17 ABX12299.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 ABX12299.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DAP3 PF10236.9 ABX12299.1 - 0.12 11.6 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 EMC3_TMCO1 PF01956.16 ABX12300.1 - 8.3e-16 58.2 13.7 2.7e-15 56.5 13.7 1.7 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Cytidylate_kin2 PF13189.6 ABX12301.1 - 8.5e-14 52.1 0.1 2.5e-13 50.5 0.1 1.7 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 ABX12301.1 - 7.9e-12 45.8 0.0 1.1e-11 45.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ABX12301.1 - 6.3e-10 39.6 0.1 1.1e-09 38.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 ABX12301.1 - 1.7e-07 31.5 0.4 7e-07 29.5 0.4 1.8 1 1 0 1 1 1 1 Shikimate kinase Cytidylate_kin PF02224.18 ABX12301.1 - 5.4e-07 29.6 1.0 5e-05 23.1 0.0 2.2 1 1 1 2 2 2 1 Cytidylate kinase ADK PF00406.22 ABX12301.1 - 1.4e-05 25.3 0.8 4.9e-05 23.5 0.0 2.1 2 1 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.6 ABX12301.1 - 2.4e-05 24.6 0.0 4.3e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ABX12301.1 - 5.1e-05 23.5 0.0 0.00087 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ABX12301.1 - 0.0002 21.8 0.1 0.00035 21.0 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ABX12301.1 - 0.0045 17.4 0.0 0.0085 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase KTI12 PF08433.10 ABX12301.1 - 0.0046 16.4 0.2 0.013 14.9 0.1 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 ABX12301.1 - 0.0052 17.2 0.0 0.0058 17.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 ABX12301.1 - 0.0058 16.6 0.2 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 ABX12301.1 - 0.0068 16.1 0.3 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 ABX12301.1 - 0.0093 15.8 0.4 0.26 11.1 0.0 2.2 2 1 0 2 2 2 1 Deoxynucleoside kinase AAA_22 PF13401.6 ABX12301.1 - 0.014 15.6 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ABX12301.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 ABX12301.1 - 0.023 14.6 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 NTPase Hydin_ADK PF17213.3 ABX12301.1 - 0.041 14.2 0.1 0.063 13.6 0.1 1.6 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_14 PF13173.6 ABX12301.1 - 0.044 13.8 0.1 0.14 12.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain RTX_C PF08339.10 ABX12301.1 - 0.055 13.5 0.9 0.084 12.9 0.9 1.3 1 0 0 1 1 1 0 RTX C-terminal domain NMT1_3 PF16868.5 ABX12301.1 - 0.075 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family Zeta_toxin PF06414.12 ABX12301.1 - 0.12 11.7 0.3 0.91 8.8 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin TruB_N PF01509.18 ABX12302.1 - 8.4e-25 87.9 1.7 3e-14 53.6 0.0 3.6 2 1 1 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 ABX12302.1 - 3.8e-20 71.8 0.2 1.2e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 ABX12302.1 - 1.1e-17 63.7 0.2 2.3e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 PUA domain DKCLD PF08068.12 ABX12302.1 - 2e-11 43.7 0.0 4.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 DKCLD (NUC011) domain FlgD_ig PF13860.6 ABX12303.1 - 0.00072 19.4 0.1 0.0023 17.8 0.0 1.9 1 1 0 1 1 1 1 FlgD Ig-like domain DM13 PF10517.9 ABX12304.1 - 1.3e-19 70.7 0.0 2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Electron transfer DM13 MCR_alpha_N PF02745.15 ABX12304.1 - 0.15 11.4 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain DAO PF01266.24 ABX12305.1 - 2.2e-45 155.8 0.0 2.7e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 ABX12305.1 - 1.5e-14 53.5 0.0 5.6e-07 28.5 0.0 2.3 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 ABX12305.1 - 8.2e-07 28.5 2.9 0.011 15.0 0.2 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABX12305.1 - 5.4e-06 26.9 4.2 0.015 15.8 0.0 4.3 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABX12305.1 - 0.0014 18.8 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABX12305.1 - 0.0083 14.9 1.8 0.57 8.8 0.0 2.5 2 1 1 3 3 3 2 HI0933-like protein Thi4 PF01946.17 ABX12305.1 - 0.038 13.2 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 ABX12305.1 - 0.062 12.2 0.3 7 5.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 ABX12305.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FixQ PF05545.11 ABX12305.1 - 0.3 11.1 1.1 19 5.3 0.2 2.8 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ ChuX_HutX PF06228.13 ABX12307.1 - 3e-07 30.3 0.0 3.6e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX HemS PF05171.12 ABX12307.1 - 0.011 15.7 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain 2-Hacid_dh_C PF02826.19 ABX12308.1 - 1.2e-65 220.2 0.1 1.6e-65 219.8 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ABX12308.1 - 1.8e-29 102.1 0.0 2e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ABX12308.1 - 1.5e-09 38.2 0.1 2.6e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ABX12308.1 - 1.4e-06 28.0 0.1 2.6e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 ABX12308.1 - 0.00017 22.1 0.0 0.00044 20.8 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent POR_N PF01855.19 ABX12309.1 - 3.8e-56 190.4 0.0 5.6e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 ABX12309.1 - 8.8e-29 100.8 0.0 1.6e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 ABX12309.1 - 4.9e-12 46.0 0.0 1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 ABX12309.1 - 1.1e-06 28.6 0.1 5.4e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain TPP_enzyme_N PF02776.18 ABX12309.1 - 0.0025 17.5 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ABX12310.1 - 5.3e-29 101.0 0.4 8.1e-29 100.4 0.4 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 ABX12310.1 - 4.5e-16 58.7 0.5 1.3e-14 54.1 0.5 2.4 1 1 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Prefoldin PF02996.17 ABX12311.1 - 0.11 12.4 0.1 0.38 10.7 0.2 1.8 2 0 0 2 2 2 0 Prefoldin subunit DUF2854 PF11016.8 ABX12311.1 - 0.15 11.9 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) TIR-like PF10137.9 ABX12314.1 - 0.077 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain F420_ligase PF01996.16 ABX12315.1 - 1.4e-45 155.6 0.6 1.7e-45 155.3 0.6 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase DUF3906 PF13046.6 ABX12315.1 - 0.088 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) Aconitase PF00330.20 ABX12316.1 - 5.3e-91 305.9 4.2 4.1e-89 299.7 4.2 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ABX12317.1 - 2.6e-21 76.3 0.2 7.9e-20 71.5 0.0 2.2 2 1 1 3 3 3 2 Aconitase C-terminal domain Aconitase_2_N PF06434.13 ABX12317.1 - 0.0044 16.7 0.2 0.026 14.2 0.2 2.0 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus MazE_antitoxin PF04014.18 ABX12317.1 - 0.026 14.4 0.1 0.066 13.2 0.1 1.7 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin Aconitase PF00330.20 ABX12318.1 - 2.8e-154 514.5 0.0 3.2e-154 514.4 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 ABX12318.1 - 0.0094 14.7 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Aconitase_C PF00694.19 ABX12319.1 - 5.5e-36 123.8 0.0 9.8e-36 123.0 0.0 1.4 2 0 0 2 2 2 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 ABX12319.1 - 0.0009 18.9 0.1 0.02 14.5 0.1 2.1 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus FAD_syn PF06574.12 ABX12319.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase NAGLU_N PF12971.7 ABX12319.1 - 0.1 12.4 0.2 0.63 9.9 0.1 2.0 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain NTP_transferase PF00483.23 ABX12320.1 - 1.2e-20 74.2 0.4 1.4e-20 74.0 0.4 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ABX12320.1 - 1.1e-10 42.1 0.0 1.3e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 ABX12320.1 - 0.0065 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase IspD PF01128.19 ABX12320.1 - 0.011 15.5 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Ribosomal_S9 PF00380.19 ABX12321.1 - 1.5e-34 119.1 0.3 1.7e-34 118.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 NFACT-R_1 PF05670.13 ABX12321.1 - 0.035 14.7 0.0 0.055 14.1 0.0 1.3 1 0 0 1 1 1 0 NFACT protein RNA binding domain Ribosomal_L13 PF00572.18 ABX12322.1 - 1.5e-09 38.2 0.4 9.2e-08 32.4 0.4 2.2 1 1 0 1 1 1 1 Ribosomal protein L13 Ribosomal_L18 PF17135.4 ABX12323.1 - 3.3e-08 33.1 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ABX12323.1 - 3.2e-05 24.6 0.2 5.2e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5450 PF17529.2 ABX12323.1 - 0.086 13.0 0.7 1.7 8.8 0.1 2.0 1 1 0 2 2 2 0 Family of unknown function (DUF5450) RNA_pol_A_bac PF01000.26 ABX12324.1 - 5.5e-26 91.1 0.0 1.3e-25 89.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ABX12324.1 - 1.2e-12 47.1 0.0 1.4e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2401 PF10287.9 ABX12324.1 - 0.15 11.6 0.4 0.24 11.0 0.4 1.2 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) SBDS PF01172.18 ABX12326.1 - 4.5e-22 77.9 0.2 1.2e-21 76.5 0.1 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 ABX12326.1 - 1.1e-17 64.1 0.5 1.1e-17 64.1 0.5 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain EFG_C PF00679.24 ABX12326.1 - 0.005 16.8 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus Phage_portal PF04860.12 ABX12326.1 - 0.07 12.3 0.1 0.16 11.1 0.0 1.5 1 1 0 1 1 1 0 Phage portal protein KH_1 PF00013.29 ABX12327.1 - 4.4e-08 32.8 0.1 9.3e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_6 PF15985.5 ABX12327.1 - 1.9e-07 31.3 0.0 3.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 ABX12327.1 - 3.5e-05 23.6 0.0 7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 ABX12327.1 - 0.079 12.8 0.0 0.28 11.1 0.0 2.0 1 1 0 1 1 1 0 KH domain ECR1_N PF14382.6 ABX12327.1 - 0.13 12.0 0.3 0.3 10.9 0.3 1.6 1 1 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region RNase_PH PF01138.21 ABX12328.1 - 2.9e-35 121.6 0.0 4e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ABX12328.1 - 3.5e-14 52.6 0.3 7.9e-14 51.4 0.3 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 ABX12329.1 - 2.3e-24 86.4 0.0 3.9e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ABX12329.1 - 6.4e-14 51.7 0.1 2.7e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Ribosomal_L37ae PF01780.19 ABX12330.1 - 2.2e-18 66.1 3.2 2.3e-18 66.0 3.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 ABX12330.1 - 0.00079 19.4 2.1 0.00079 19.4 2.1 1.6 2 0 0 2 2 2 1 Transposase zinc-ribbon domain C1_1 PF00130.22 ABX12330.1 - 0.013 15.4 1.6 0.017 15.0 1.6 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rep_fac-A_C PF08646.10 ABX12330.1 - 0.04 13.7 0.8 0.04 13.6 0.8 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-RRN7 PF11781.8 ABX12330.1 - 0.047 13.4 1.0 0.071 12.8 0.2 1.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 OrfB_Zn_ribbon PF07282.11 ABX12330.1 - 0.048 13.6 2.9 0.12 12.3 2.9 1.8 1 1 0 1 1 1 0 Putative transposase DNA-binding domain C1_2 PF03107.16 ABX12330.1 - 0.055 13.8 0.5 0.074 13.4 0.5 1.2 1 0 0 1 1 1 0 C1 domain TF_Zn_Ribbon PF08271.12 ABX12330.1 - 0.066 12.7 1.9 0.13 11.8 1.9 1.5 1 1 0 1 1 1 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ABX12330.1 - 0.089 12.9 0.4 0.089 12.9 0.4 2.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_3 PF13878.6 ABX12330.1 - 0.2 11.5 2.2 7.9 6.4 0.3 2.2 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO Pcc1 PF09341.10 ABX12331.1 - 1.2e-07 31.7 0.1 1.4e-07 31.6 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Prefoldin_2 PF01920.20 ABX12332.1 - 2.7e-20 72.3 25.3 3.1e-20 72.1 25.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit FixO PF02433.15 ABX12332.1 - 0.14 11.6 4.3 0.18 11.2 4.3 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO FAP206 PF12018.8 ABX12332.1 - 0.29 10.6 11.1 1.1 8.7 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function PDE4_UCR PF18100.1 ABX12332.1 - 0.43 11.2 9.1 0.68 10.6 9.1 1.3 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) Bac_DNA_binding PF00216.21 ABX12332.1 - 0.66 10.2 7.6 0.32 11.2 2.8 2.1 2 0 0 2 2 2 0 Bacterial DNA-binding protein Ntox28 PF15605.6 ABX12332.1 - 1.3 9.3 8.1 2.2 8.6 0.7 2.1 2 0 0 2 2 2 0 Bacterial toxin 28 FapA PF03961.13 ABX12332.1 - 1.4 7.4 13.6 1.7 7.1 13.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GAS PF13851.6 ABX12332.1 - 1.6 8.0 23.5 2.9 7.2 23.5 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CdvA PF18822.1 ABX12332.1 - 1.9 8.3 18.6 3.3 7.5 2.6 2.4 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Nup88 PF10168.9 ABX12332.1 - 2 6.1 17.0 2.6 5.7 17.0 1.0 1 0 0 1 1 1 0 Nuclear pore component ERCC4 PF02732.15 ABX12333.1 - 3.9e-23 82.4 0.0 6.2e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 ABX12333.1 - 7e-10 39.4 0.1 4.2e-09 36.9 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 ABX12333.1 - 2.9e-07 30.0 0.0 0.0059 16.4 0.1 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_2 PF12826.7 ABX12333.1 - 3e-05 24.0 0.0 0.00026 21.0 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 ABX12333.1 - 7.5e-05 22.9 0.0 0.013 15.7 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_8 PF14716.6 ABX12333.1 - 0.0066 16.8 0.2 0.37 11.2 0.1 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix domain 5_3_exonuc PF01367.20 ABX12333.1 - 0.021 15.4 0.1 0.056 14.0 0.1 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_1 PF00515.28 ABX12334.1 - 1.1e-17 63.0 0.0 8.8e-05 22.2 0.2 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ABX12334.1 - 6.8e-17 60.2 0.0 2.9e-05 23.8 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 ABX12334.1 - 1.3e-14 53.1 0.1 0.032 14.4 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 ABX12334.1 - 4.8e-11 43.0 0.0 8.2e-05 23.0 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ABX12334.1 - 9.1e-10 38.2 0.3 0.0047 17.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ABX12334.1 - 1.5e-09 37.8 0.0 0.00091 19.8 0.0 3.5 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 ABX12334.1 - 5.3e-09 36.2 0.0 0.078 13.3 0.0 3.5 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 ABX12334.1 - 9.1e-09 35.4 0.0 0.062 14.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ABX12334.1 - 2e-08 33.7 0.0 0.0013 18.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ABX12334.1 - 4.3e-08 33.3 0.0 3.3e-05 24.0 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 ABX12334.1 - 1.5e-07 31.0 1.1 0.00019 21.0 0.0 3.4 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 ABX12334.1 - 5.7e-07 30.1 0.0 0.023 15.3 0.0 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 ABX12334.1 - 0.00027 21.0 0.0 0.095 12.9 0.0 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 ABX12334.1 - 0.00064 19.5 0.3 2 8.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 ABX12334.1 - 0.036 13.0 0.0 0.61 8.9 0.0 2.0 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 ABX12334.1 - 0.072 13.4 0.0 0.45 10.9 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 ABX12334.1 - 0.14 11.3 0.0 4.8 6.3 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat PIN_6 PF17146.4 ABX12335.1 - 4.9e-18 65.4 0.0 7.2e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 PIN domain of ribonuclease PIN_5 PF08745.11 ABX12335.1 - 6.6e-07 29.0 0.2 0.0002 20.8 0.1 2.1 2 0 0 2 2 2 2 PINc domain ribonuclease PIN PF01850.21 ABX12335.1 - 0.0029 18.1 0.1 0.0048 17.4 0.1 1.4 1 1 0 1 1 1 1 PIN domain RecR PF02132.15 ABX12335.1 - 0.0078 15.8 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 RecR protein zf-C3HC4_3 PF13920.6 ABX12335.1 - 0.059 13.2 1.5 0.11 12.4 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 ABX12335.1 - 2.4 8.3 5.1 12 6.1 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 NAD_kinase PF01513.21 ABX12336.1 - 1.5e-36 126.1 0.3 2.2e-36 125.6 0.3 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 ABX12336.1 - 1.2e-06 28.1 0.2 2.4e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CoA_binding_2 PF13380.6 ABX12336.1 - 0.025 15.1 0.0 0.055 14.0 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain Rhodanese PF00581.20 ABX12337.1 - 1.5e-34 118.7 0.1 3.1e-18 66.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain CDH1_2_SANT_HL1 PF18375.1 ABX12338.1 - 0.045 14.4 0.0 0.17 12.6 0.0 1.7 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Fer4 PF00037.27 ABX12339.1 - 1.3e-07 31.1 16.0 0.00038 20.1 3.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 ABX12339.1 - 2.1e-05 24.6 3.9 4e-05 23.7 3.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABX12339.1 - 4.7e-05 23.9 5.9 0.00053 20.5 6.9 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 ABX12339.1 - 0.00012 22.1 5.9 0.0003 20.8 5.9 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain ETF_QO PF05187.13 ABX12339.1 - 0.00078 19.5 0.5 0.0016 18.5 0.5 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Tenui_PVC2 PF06656.11 ABX12339.1 - 0.0015 16.6 0.2 0.002 16.1 0.2 1.1 1 0 0 1 1 1 1 Tenuivirus PVC2 protein Fer4_21 PF14697.6 ABX12339.1 - 0.0016 18.5 4.8 0.0037 17.4 4.8 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ABX12339.1 - 0.0076 16.7 1.3 3.2 8.3 0.0 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABX12339.1 - 0.0078 16.3 13.2 0.01 15.8 1.6 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_17 PF13534.6 ABX12339.1 - 0.025 15.1 1.8 9.9 6.8 0.0 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Me-amine-dh_L PF02975.14 ABX12339.1 - 0.11 13.0 2.7 0.2 12.2 2.7 1.3 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain Fer4_16 PF13484.6 ABX12339.1 - 0.18 12.7 8.3 2.9 8.9 2.7 2.9 1 1 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 ABX12339.1 - 4.8 7.5 9.8 7.5 6.9 0.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 ABX12339.1 - 6.9 7.9 15.3 11 7.2 5.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Glyco_tranf_2_3 PF13641.6 ABX12340.1 - 1.1e-24 87.6 0.0 1.7e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ABX12340.1 - 3.1e-21 76.2 0.4 6.4e-21 75.2 0.4 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ABX12340.1 - 2.7e-18 66.3 0.1 4.6e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ABX12340.1 - 4.9e-13 48.9 0.1 8.6e-13 48.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 ABX12340.1 - 0.00063 18.4 2.5 0.00099 17.7 0.2 2.0 2 0 0 2 2 2 1 Cellulose synthase Glyco_tranf_2_4 PF13704.6 ABX12340.1 - 0.025 15.1 0.3 0.099 13.2 0.3 2.0 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF1664 PF07889.12 ABX12341.1 - 2.1e-05 24.5 38.2 0.02 14.9 1.2 5.3 1 1 4 6 6 6 5 Protein of unknown function (DUF1664) Sec34 PF04136.15 ABX12341.1 - 0.00082 19.3 34.3 0.072 13.0 0.2 6.3 1 1 5 7 7 7 2 Sec34-like family CENP-Q PF13094.6 ABX12341.1 - 0.0016 18.7 11.8 0.0016 18.7 11.8 3.7 3 2 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF948 PF06103.11 ABX12341.1 - 0.0022 18.2 26.0 0.39 11.0 0.4 5.9 1 1 2 4 4 4 2 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 ABX12341.1 - 0.0023 18.0 32.4 0.0078 16.3 0.9 5.3 1 1 4 6 6 6 1 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 ABX12341.1 - 0.0056 17.1 34.0 0.3 11.6 0.6 6.9 2 1 4 6 6 5 3 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 ABX12341.1 - 0.019 15.0 41.5 0.039 14.0 6.6 4.8 1 1 4 6 6 6 0 Laminin Domain II DUF5063 PF16702.5 ABX12341.1 - 0.061 13.7 0.9 0.23 11.9 0.9 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) KxDL PF10241.9 ABX12341.1 - 0.074 13.3 33.2 0.52 10.6 1.3 6.9 4 2 1 6 6 5 0 Uncharacterized conserved protein BLOC1_2 PF10046.9 ABX12341.1 - 0.13 12.5 39.9 0.74 10.2 1.0 6.6 1 1 7 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4844 PF16133.5 ABX12341.1 - 0.15 12.6 4.6 0.32 11.6 2.6 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4844) MCPsignal PF00015.21 ABX12341.1 - 0.37 10.6 40.3 0.63 9.8 1.7 5.7 1 1 6 7 7 7 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SesA PF17107.5 ABX12341.1 - 0.47 10.6 30.8 0.56 10.4 6.1 5.2 1 1 3 5 5 5 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1192 PF06698.11 ABX12341.1 - 1.1 9.3 5.7 23 5.1 0.3 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) SlyX PF04102.12 ABX12341.1 - 1.9 9.2 20.7 40 4.9 0.2 6.7 2 1 5 7 7 7 0 SlyX RPW8 PF05659.11 ABX12341.1 - 2.3 7.9 24.7 0.42 10.3 0.3 5.8 1 1 3 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CorA PF01544.18 ABX12341.1 - 2.6 7.3 19.9 0.97 8.7 0.5 3.5 1 1 2 4 4 4 0 CorA-like Mg2+ transporter protein DUF1706 PF08020.11 ABX12341.1 - 5.2 7.0 9.8 0.81 9.6 3.6 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1706) ATG16 PF08614.11 ABX12341.1 - 9.5 6.4 34.3 0.52 10.5 4.7 3.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Na_H_Exchanger PF00999.21 ABX12342.1 - 2.7e-52 177.8 53.8 3.4e-52 177.5 53.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Spore_YabQ PF09578.10 ABX12342.1 - 0.00016 21.8 0.2 0.00016 21.8 0.2 4.5 6 1 0 6 6 6 1 Spore cortex protein YabQ (Spore_YabQ) JmjN PF02375.17 ABX12344.1 - 0.0032 17.4 0.4 0.0056 16.6 0.4 1.4 1 0 0 1 1 1 1 jmjN domain Syntaxin_2 PF14523.6 ABX12344.1 - 0.019 15.3 0.9 0.023 15.1 0.9 1.2 1 0 0 1 1 1 0 Syntaxin-like protein ssDNA-exonuc_C PF10141.9 ABX12344.1 - 0.02 14.5 0.4 0.027 14.1 0.4 1.4 1 1 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain Ribosomal_L16 PF00252.18 ABX12345.1 - 1.1e-26 93.3 0.9 1.4e-26 93.1 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e tRNA_int_endo PF01974.17 ABX12346.1 - 3.9e-21 74.9 0.4 1.3e-20 73.2 0.1 1.9 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 ABX12346.1 - 1.5e-14 53.4 3.6 3.1e-13 49.2 0.7 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Response_reg PF00072.24 ABX12348.1 - 1.8e-23 82.8 1.0 2.2e-23 82.6 1.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Peripla_BP_4 PF13407.6 ABX12348.1 - 0.025 14.2 0.1 0.031 13.9 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain PglD_N PF17836.1 ABX12348.1 - 0.066 13.8 0.5 0.15 12.7 0.5 1.8 1 1 1 2 2 2 0 PglD N-terminal domain B12-binding PF02310.19 ABX12348.1 - 0.092 12.8 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 B12 binding domain 2-Hacid_dh PF00389.30 ABX12348.1 - 0.16 11.6 1.5 11 5.6 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Sigma_reg_N PF13800.6 ABX12353.1 - 0.2 12.0 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Rax2 PF12768.7 ABX12354.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity FixH PF05751.11 ABX12354.1 - 0.1 12.6 0.1 0.18 11.8 0.0 1.5 2 0 0 2 2 2 0 FixH DUF1737 PF08410.10 ABX12355.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) CHASE3 PF05227.13 ABX12356.1 - 4e-52 175.8 9.3 6.3e-31 107.1 0.1 3.1 3 1 0 3 3 3 2 CHASE3 domain HATPase_c PF02518.26 ABX12356.1 - 6.9e-17 62.0 0.1 3.2e-16 59.8 0.0 2.1 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABX12356.1 - 1e-12 47.9 0.4 5.9e-12 45.5 0.4 2.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 ABX12356.1 - 1.5e-07 31.3 0.2 5.4e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 GHKL domain HAMP PF00672.25 ABX12356.1 - 1.6e-07 31.5 0.0 3.4e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 HAMP domain 4HB_MCP_1 PF12729.7 ABX12356.1 - 0.0036 16.9 0.0 0.0036 16.9 0.0 3.5 3 1 0 3 3 3 1 Four helix bundle sensory module for signal transduction HATPase_c_2 PF13581.6 ABX12356.1 - 0.064 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HEAT_2 PF13646.6 ABX12358.1 - 6.1e-12 45.8 0.2 2.9e-11 43.6 0.2 1.8 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 ABX12358.1 - 0.00023 21.1 0.5 2.2 8.8 0.0 3.4 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 ABX12358.1 - 0.006 16.6 0.1 0.022 14.8 0.1 2.0 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Nnf1 PF03980.14 ABX12358.1 - 0.1 13.0 0.1 0.26 11.7 0.0 1.6 2 0 0 2 2 2 0 Nnf1 EamA PF00892.20 ABX12359.1 - 1.7e-29 102.7 30.2 2.5e-16 60.1 6.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 ABX12359.1 - 2.5e-07 30.3 20.4 4.6e-07 29.5 20.4 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family SLC35F PF06027.12 ABX12359.1 - 1.1e-05 25.1 17.4 1.4e-05 24.8 17.4 1.1 1 0 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 ABX12359.1 - 3.7e-05 23.1 3.2 3.7e-05 23.1 3.2 2.6 1 1 0 3 3 3 1 Purine nucleobase transmembrane transport Sugar_transport PF06800.12 ABX12359.1 - 6.1e-05 22.5 19.3 0.00011 21.6 2.2 2.2 1 1 1 2 2 2 2 Sugar transport protein TMEM234 PF10639.9 ABX12359.1 - 0.0013 18.7 1.8 0.0013 18.7 1.8 2.4 2 1 0 2 2 2 1 Putative transmembrane family 234 HTH_45 PF14947.6 ABX12360.1 - 0.018 15.0 0.1 0.051 13.6 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix Response_reg PF00072.24 ABX12361.1 - 1.3e-21 76.9 3.6 1.5e-21 76.6 3.6 1.1 1 0 0 1 1 1 1 Response regulator receiver domain NKWYS PF10364.9 ABX12361.1 - 0.014 15.5 0.4 0.019 15.1 0.4 1.3 1 1 0 1 1 1 0 Putative capsular polysaccharide synthesis protein HAD PF12710.7 ABX12361.1 - 0.026 15.0 0.0 0.027 14.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Scm3 PF10384.9 ABX12361.1 - 0.081 12.7 0.1 15 5.4 0.0 2.5 2 0 0 2 2 2 0 Centromere protein Scm3 Mistic PF11458.8 ABX12361.1 - 0.1 12.5 2.5 0.14 12.2 0.7 2.0 1 1 1 2 2 2 0 Membrane-integrating protein Mistic TPR_1 PF00515.28 ABX12364.1 - 4.7e-13 48.3 0.5 0.00062 19.5 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 ABX12364.1 - 5.1e-12 46.1 0.4 1.9e-08 34.7 0.2 2.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ABX12364.1 - 5.7e-11 41.6 0.1 0.011 15.7 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ABX12364.1 - 3.5e-08 33.0 0.1 0.04 14.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ABX12364.1 - 7.1e-08 32.6 0.0 0.042 14.7 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ABX12364.1 - 1.8e-06 28.1 0.0 2.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ABX12364.1 - 7.8e-06 25.6 0.0 0.97 9.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ABX12364.1 - 0.00028 21.1 0.0 0.13 12.5 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 ABX12364.1 - 0.00091 18.5 0.0 0.0059 15.9 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ABX12364.1 - 0.0011 19.0 0.6 0.017 15.1 0.1 2.7 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 ABX12364.1 - 0.0045 16.6 1.8 3.8 7.3 0.0 3.3 3 1 0 3 3 3 2 TPR repeat NARP1 PF12569.8 ABX12364.1 - 0.0077 15.2 0.1 0.014 14.3 0.0 1.4 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_17 PF13431.6 ABX12364.1 - 0.0084 16.4 1.2 17 6.1 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 ABX12364.1 - 0.0084 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat ChAPs PF09295.10 ABX12364.1 - 0.014 14.4 0.0 0.015 14.3 0.0 1.0 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 ABX12364.1 - 0.031 14.1 0.0 26 4.9 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 ABX12364.1 - 0.036 14.7 0.0 0.22 12.2 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat HTH_Tnp_Tc5 PF03221.16 ABX12365.1 - 0.026 14.6 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain CSTF2_hinge PF14327.6 ABX12365.1 - 0.14 12.6 0.1 0.24 11.9 0.1 1.3 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Lipoprotein_10 PF03202.13 ABX12366.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region Beta_propel PF09826.9 ABX12367.1 - 7.5e-154 513.4 15.3 8.8e-154 513.1 15.3 1.0 1 0 0 1 1 1 1 Beta propeller domain LVIVD PF08309.11 ABX12367.1 - 0.078 12.3 5.4 9.8 5.6 0.1 4.3 4 0 0 4 4 4 0 LVIVD repeat HTH_5 PF01022.20 ABX12368.1 - 2.1e-08 33.9 0.5 6.7e-08 32.3 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABX12368.1 - 5.4e-08 32.8 0.0 9.2e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 ABX12368.1 - 6e-08 32.1 0.1 1.2e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TFIIE_alpha PF02002.17 ABX12368.1 - 3.4e-05 23.6 0.3 6e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_11 PF08279.12 ABX12368.1 - 4.8e-05 23.2 0.4 0.00012 21.9 0.4 1.6 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 ABX12368.1 - 6.3e-05 22.8 0.1 0.00011 22.0 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.16 ABX12368.1 - 0.00025 20.5 0.0 0.00051 19.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 ABX12368.1 - 0.00099 19.0 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 MarR family Sigma70_r4_2 PF08281.12 ABX12368.1 - 0.005 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 ABX12368.1 - 0.013 16.0 0.1 0.022 15.2 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TnsD PF15978.5 ABX12368.1 - 0.021 13.8 0.6 0.028 13.4 0.6 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D Rrf2 PF02082.20 ABX12368.1 - 0.021 15.2 0.1 0.047 14.0 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator GerE PF00196.19 ABX12368.1 - 0.052 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_34 PF13601.6 ABX12368.1 - 0.055 13.7 0.7 0.1 12.8 0.7 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_27 PF13463.6 ABX12368.1 - 0.11 13.0 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain F420H2_quin_red PF04075.14 ABX12369.1 - 1.2e-05 25.5 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DUF2255 PF10012.9 ABX12369.1 - 0.0015 18.7 0.1 0.0017 18.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2255) LPD28 PF18843.1 ABX12369.1 - 0.031 13.9 0.1 0.035 13.7 0.1 1.3 1 1 0 1 1 1 0 Large polyvalent protein associated domain 28 PRC PF05239.16 ABX12370.1 - 1.9e-08 34.3 0.6 0.00043 20.3 0.1 2.2 2 0 0 2 2 2 2 PRC-barrel domain DUF2171 PF09939.9 ABX12370.1 - 7.5e-05 22.9 0.7 0.039 14.2 0.2 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2171) ABC_tran PF00005.27 ABX12371.1 - 1.2e-31 110.1 0.0 2.2e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABX12371.1 - 7.3e-11 42.4 2.1 4.8e-07 29.9 0.2 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 ABX12371.1 - 3.5e-09 37.2 0.4 8.2e-09 36.1 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 ABX12371.1 - 0.0012 18.6 1.8 0.18 11.5 0.0 2.7 2 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 ABX12371.1 - 0.0035 17.0 0.2 0.0079 15.9 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ABX12371.1 - 0.011 16.3 4.1 0.011 16.2 2.2 2.1 1 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 ABX12371.1 - 0.014 14.8 0.2 0.068 12.6 0.2 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain UCH_N PF16674.5 ABX12371.1 - 0.078 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 AAA_27 PF13514.6 ABX12371.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 ABX12372.1 - 3.2e-33 114.9 19.0 3.2e-33 114.9 19.0 1.9 1 1 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 ABX12372.1 - 4.4e-14 52.3 30.3 5.3e-14 52.1 30.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 ABX12372.1 - 0.00012 21.5 27.9 0.0012 18.2 27.9 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein NHL PF01436.21 ABX12373.1 - 5.8e-30 101.8 1.3 0.00011 22.0 0.0 6.6 6 0 0 6 6 6 5 NHL repeat HemolysinCabind PF00353.19 ABX12373.1 - 1.6e-20 72.7 45.3 1.9e-08 34.1 12.2 3.7 1 1 1 3 3 3 3 RTX calcium-binding nonapeptide repeat (4 copies) SGL PF08450.12 ABX12373.1 - 5.1e-09 36.1 0.6 0.00072 19.2 0.1 4.3 2 2 2 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 ABX12373.1 - 8.6e-08 31.7 10.1 0.00026 20.3 2.8 3.0 2 1 1 3 3 3 2 6-bladed beta-propeller SBBP PF06739.11 ABX12373.1 - 2.4e-07 30.6 16.2 0.007 16.3 1.0 5.9 7 0 0 7 7 7 3 Beta-propeller repeat TolB_like PF15869.5 ABX12373.1 - 3.2e-06 26.6 1.4 0.041 13.1 0.1 2.4 1 1 1 2 2 2 2 TolB-like 6-blade propeller-like HYR PF02494.16 ABX12373.1 - 0.0015 18.8 0.1 0.0034 17.7 0.1 1.7 1 0 0 1 1 1 1 HYR domain Arylesterase PF01731.20 ABX12373.1 - 0.0039 17.3 0.6 1.6 8.9 0.0 3.5 4 0 0 4 4 4 1 Arylesterase LVIVD PF08309.11 ABX12373.1 - 0.0059 15.9 6.7 0.88 8.9 0.2 3.6 4 0 0 4 4 4 2 LVIVD repeat Phytase-like PF13449.6 ABX12373.1 - 0.011 15.7 0.1 1 9.2 0.0 2.9 1 1 2 3 3 3 0 Esterase-like activity of phytase SdiA-regulated PF06977.11 ABX12373.1 - 0.15 11.3 0.1 5.8 6.1 0.0 2.5 2 1 1 3 3 3 0 SdiA-regulated DUF866 PF05907.13 ABX12374.1 - 0.022 14.6 0.6 0.93 9.4 0.1 3.1 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF866) NTP_transf_2 PF01909.23 ABX12374.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain PBP_like_2 PF12849.7 ABX12375.1 - 2.6e-57 194.6 1.1 3.5e-57 194.2 1.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.25 ABX12375.1 - 1e-15 58.5 1.6 1.4e-15 58.1 1.6 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 ABX12375.1 - 3e-06 26.5 0.0 8.6e-06 25.0 0.0 1.7 1 1 0 1 1 1 1 PBP superfamily domain BPD_transp_1 PF00528.22 ABX12377.1 - 1.2e-17 64.2 16.7 1.2e-17 64.2 16.7 2.2 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF1385 PF07136.11 ABX12377.1 - 2.5 7.3 6.9 2.7 7.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1385) BPD_transp_1 PF00528.22 ABX12378.1 - 5.2e-18 65.4 20.0 6.8e-18 65.1 14.1 2.1 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component DUF3333 PF11812.8 ABX12378.1 - 0.45 10.7 4.0 0.56 10.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) DUF3413 PF11893.8 ABX12378.1 - 2.6 7.2 8.5 2.5 7.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3413) ABC_tran PF00005.27 ABX12379.1 - 5.9e-30 104.6 0.0 9.2e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABX12379.1 - 8.5e-12 45.5 0.0 9.5e-05 22.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABX12379.1 - 2e-10 40.5 0.2 5.6e-10 39.0 0.2 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABX12379.1 - 3.5e-06 27.3 0.0 8.1e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ABX12379.1 - 8.3e-06 25.7 1.5 3e-05 23.9 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 ABX12379.1 - 5.6e-05 23.7 1.7 0.00016 22.3 1.7 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABX12379.1 - 7.6e-05 22.7 0.4 0.00014 21.8 0.1 1.5 2 0 0 2 2 2 1 RsgA GTPase Rad17 PF03215.15 ABX12379.1 - 0.00027 20.9 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain ATPase_2 PF01637.18 ABX12379.1 - 0.0014 18.6 0.5 0.05 13.5 0.5 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 ABX12379.1 - 0.0023 17.6 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ABX12379.1 - 0.0038 17.0 0.1 0.023 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 ABX12379.1 - 0.0039 16.6 0.3 1.3 8.4 0.0 2.2 2 0 0 2 2 2 2 Bacterial TniB protein NB-ARC PF00931.22 ABX12379.1 - 0.0071 15.6 0.0 0.01 15.0 0.0 1.4 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 ABX12379.1 - 0.01 16.2 0.0 0.025 14.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 ABX12379.1 - 0.015 15.7 0.1 0.39 11.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ABX12379.1 - 0.016 14.9 0.1 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ABX12379.1 - 0.018 14.6 0.1 0.038 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ABX12379.1 - 0.018 15.6 0.0 0.041 14.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain PRK PF00485.18 ABX12379.1 - 0.031 14.0 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 ABX12379.1 - 0.031 13.4 0.1 0.035 13.3 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit TsaE PF02367.17 ABX12379.1 - 0.033 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ABX12379.1 - 0.044 13.9 0.0 0.095 12.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 ABX12379.1 - 0.062 13.6 0.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 ABX12379.1 - 0.068 12.6 0.3 0.57 9.6 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 ABX12379.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 ABX12379.1 - 0.18 12.1 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoU PF01895.19 ABX12380.1 - 4.7e-19 68.6 6.4 4.7e-09 36.6 0.2 2.3 2 0 0 2 2 2 2 PhoU domain Sec66 PF09802.9 ABX12380.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Sbt_1 PF05982.12 ABX12381.1 - 2e-102 342.6 23.8 2.3e-102 342.4 23.8 1.0 1 0 0 1 1 1 1 Na+-dependent bicarbonate transporter superfamily DUF5464 PF17552.2 ABX12381.1 - 0.63 10.3 5.9 4.8 7.5 0.3 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5464) DUF1772 PF08592.11 ABX12381.1 - 4.4 7.6 12.7 1.1 9.6 4.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) P-II PF00543.22 ABX12382.1 - 7.9e-05 23.2 0.2 0.00011 22.7 0.2 1.2 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 ABX12382.1 - 0.0045 17.1 0.1 0.014 15.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3240) DUF190 PF02641.15 ABX12382.1 - 0.0054 17.0 0.4 0.01 16.1 0.4 1.4 1 1 0 1 1 1 1 Uncharacterized ACR, COG1993 DUF4974 PF16344.5 ABX12382.1 - 0.033 14.2 0.8 3.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) Rad1 PF02144.16 ABX12382.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 Nit_Regul_Hom PF10126.9 ABX12382.1 - 0.14 12.2 1.9 5.8 7.0 0.4 2.0 1 1 1 2 2 2 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII HTH_5 PF01022.20 ABX12383.1 - 3.5e-16 58.8 0.1 6.2e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABX12383.1 - 1.9e-08 34.3 0.0 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 ABX12383.1 - 3.7e-08 32.8 0.3 1.7e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 ABX12383.1 - 0.00064 19.6 0.0 0.0035 17.3 0.0 1.9 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 ABX12383.1 - 0.00094 19.0 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 ABX12383.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_34 PF13601.6 ABX12383.1 - 0.025 14.8 0.0 0.035 14.3 0.0 1.3 1 1 0 1 1 1 0 Winged helix DNA-binding domain TFIIE_alpha PF02002.17 ABX12383.1 - 0.049 13.5 0.4 0.064 13.1 0.4 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_IclR PF09339.10 ABX12383.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.5 1 1 1 2 2 2 0 IclR helix-turn-helix domain Cdc6_C PF09079.11 ABX12383.1 - 0.059 13.4 0.1 0.077 13.0 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Penicillinase_R PF03965.16 ABX12383.1 - 0.06 13.7 0.1 0.083 13.2 0.1 1.3 1 0 0 1 1 1 0 Penicillinase repressor PH_16 PF17838.1 ABX12383.1 - 0.077 12.8 0.2 0.1 12.5 0.2 1.1 1 0 0 1 1 1 0 PH domain PaaX PF07848.12 ABX12383.1 - 0.17 12.1 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein LMWPc PF01451.21 ABX12384.1 - 1e-21 77.8 0.2 2.1e-21 76.8 0.2 1.5 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase MIP PF00230.20 ABX12385.1 - 1.6e-39 135.9 17.2 2e-39 135.6 17.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Aminotran_3 PF00202.21 ABX12386.1 - 1.2e-74 251.5 0.1 1.5e-74 251.1 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ABX12386.1 - 1.4e-05 24.4 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1_N PF03709.15 ABX12386.1 - 0.12 12.7 0.0 0.43 10.9 0.0 1.9 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Porphobil_deam PF01379.20 ABX12387.1 - 4.8e-70 235.2 0.1 1.1e-69 234.0 0.0 1.6 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 ABX12387.1 - 4.3e-12 46.2 0.0 1.6e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain TP_methylase PF00590.20 ABX12388.1 - 4.4e-51 173.8 0.0 5.1e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF600 PF04634.12 ABX12388.1 - 0.073 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF600 tRNA_int_endo PF01974.17 ABX12388.1 - 0.14 12.3 2.0 0.29 11.2 0.1 2.3 2 1 1 3 3 3 0 tRNA intron endonuclease, catalytic C-terminal domain HEM4 PF02602.15 ABX12389.1 - 7.3e-48 162.9 0.0 8.3e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD CTP_transf_like PF01467.26 ABX12389.1 - 0.075 13.2 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 Cytidylyltransferase-like Cucumo_coat PF00760.18 ABX12389.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Cucumovirus coat protein Cys_rich_CPXG PF14255.6 ABX12390.1 - 0.012 15.5 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 Cysteine-rich CPXCG zf-LITAF-like PF10601.9 ABX12390.1 - 0.014 15.6 0.1 0.019 15.2 0.1 1.2 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain SoxD PF04267.12 ABX12390.1 - 0.024 14.7 0.4 0.028 14.5 0.4 1.2 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family AP3D1 PF06375.11 ABX12390.1 - 1.4 9.2 20.0 1.4 9.1 20.0 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 SR-25 PF10500.9 ABX12390.1 - 6.3 6.3 26.8 6.6 6.3 26.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Porph_ging PF09697.10 ABX12390.1 - 7.3 7.2 9.7 8.1 7.1 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) Peptidase_S49_N PF08496.10 ABX12390.1 - 7.4 6.6 18.4 7.3 6.6 18.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3464 PF11947.8 ABX12390.1 - 9.2 6.0 11.2 8.4 6.1 11.2 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 UPF0051 PF01458.17 ABX12391.1 - 5.6e-73 245.2 0.2 7.4e-73 244.8 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) UPF0051 PF01458.17 ABX12392.1 - 8.2e-63 212.0 2.5 1.1e-62 211.6 2.5 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF4116 PF13475.6 ABX12392.1 - 0.11 12.3 0.1 0.35 10.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Aminotran_5 PF00266.19 ABX12393.1 - 8e-150 498.9 0.3 9.1e-150 498.7 0.3 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ABX12393.1 - 0.00026 19.6 0.1 0.00051 18.7 0.1 1.6 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 ABX12393.1 - 0.055 12.2 0.0 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain NifU_N PF01592.16 ABX12394.1 - 6.6e-30 103.9 0.1 7.7e-30 103.7 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain SufE PF02657.15 ABX12394.1 - 0.019 14.8 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Fe-S metabolism associated domain TSCPD PF12637.7 ABX12394.1 - 0.054 13.7 0.4 0.083 13.1 0.4 1.3 1 0 0 1 1 1 0 TSCPD domain zf-ribbon_3 PF13248.6 ABX12395.1 - 0.075 12.5 0.5 0.075 12.5 0.5 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_S27 PF01599.19 ABX12395.1 - 0.08 13.1 0.9 0.2 11.9 0.9 1.7 1 1 0 1 1 1 0 Ribosomal protein S27a PGK PF00162.19 ABX12396.1 - 2.9e-100 335.9 0.6 3.3e-100 335.7 0.6 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PAP2 PF01569.21 ABX12397.1 - 8.6e-21 74.1 0.2 8.6e-21 74.1 0.2 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ABX12397.1 - 6.5e-10 39.0 5.1 6.5e-10 39.0 5.1 2.5 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 ABX12397.1 - 0.00014 22.3 0.2 0.00014 22.3 0.2 2.8 3 0 0 3 3 3 1 PAP2 superfamily C-terminal DUF2834 PF11196.8 ABX12397.1 - 0.022 15.1 2.5 0.062 13.7 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) ATPase_gene1 PF09527.10 ABX12397.1 - 9 6.6 12.2 8.3 6.7 0.1 4.1 4 0 0 4 4 4 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter EccE PF11203.8 ABX12399.1 - 0.3 11.4 5.6 0.39 11.1 0.4 2.8 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE CorA PF01544.18 ABX12399.1 - 2.6 7.3 12.4 0.49 9.7 8.9 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 ABX12399.1 - 3.2 7.8 7.2 0.86 9.6 2.0 2.5 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 ABX12399.1 - 5.6 7.3 17.0 1.8 8.9 0.5 3.9 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3040 PF11239.8 ABX12400.1 - 0.22 11.8 1.1 0.72 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) REPA_OB_2 PF16900.5 ABX12401.1 - 0.0024 17.7 0.5 0.0026 17.6 0.5 1.1 1 0 0 1 1 1 1 Replication protein A OB domain HupF_HypC PF01455.18 ABX12401.1 - 0.11 12.6 0.8 7.6 6.8 0.1 2.1 1 1 1 2 2 2 0 HupF/HypC family HD PF01966.22 ABX12403.1 - 4.3e-16 59.2 0.3 6.3e-16 58.7 0.3 1.3 1 0 0 1 1 1 1 HD domain DUF4917 PF16263.5 ABX12403.1 - 0.017 14.5 0.1 0.032 13.6 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4917) NMT1_2 PF13379.6 ABX12403.1 - 0.19 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family JmjN PF02375.17 ABX12404.1 - 0.0021 18.0 3.0 0.081 12.9 0.2 2.4 1 1 1 2 2 2 2 jmjN domain DUF1896 PF08989.10 ABX12404.1 - 0.023 14.8 0.6 0.03 14.4 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1896) TRAF_BIRC3_bd PF16673.5 ABX12404.1 - 0.035 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain ALAD PF00490.21 ABX12405.1 - 1.1e-136 455.2 0.9 1.2e-136 455.1 0.9 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase GlutR_N PF05201.15 ABX12406.1 - 7.2e-38 129.6 0.2 1.8e-37 128.3 0.2 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 ABX12406.1 - 1.1e-28 100.1 0.3 2.4e-28 98.9 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 ABX12406.1 - 3.7e-19 69.0 1.7 1.3e-18 67.3 1.7 2.0 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 ABX12406.1 - 0.00055 20.5 0.0 0.002 18.7 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ABX12406.1 - 0.0011 18.4 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAM25 PF15825.5 ABX12406.1 - 0.053 13.9 0.8 0.26 11.7 0.7 2.3 1 1 0 1 1 1 0 FAM25 family NAD_binding_7 PF13241.6 ABX12406.1 - 0.1 13.0 0.0 0.31 11.5 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3420 PF11900.8 ABX12406.1 - 0.59 10.3 3.7 1.3 9.3 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) DUF4795 PF16043.5 ABX12406.1 - 2.2 7.8 15.8 0.058 13.0 6.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) NAD_binding_7 PF13241.6 ABX12407.1 - 1.3e-20 73.7 1.2 2.6e-20 72.8 0.2 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 ABX12407.1 - 4.3e-06 26.8 0.6 7.2e-06 26.1 0.6 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sirohm_synth_M PF14824.6 ABX12407.1 - 0.00051 19.4 0.1 0.0013 18.1 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central SKI PF01202.22 ABX12407.1 - 0.0094 16.1 1.2 0.013 15.7 0.1 1.9 3 0 0 3 3 3 1 Shikimate kinase THF_DHG_CYH_C PF02882.19 ABX12407.1 - 0.016 14.6 0.2 0.032 13.5 0.2 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 ABX12407.1 - 0.025 14.8 0.1 0.047 13.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Oxidored_nitro PF00148.19 ABX12407.1 - 0.042 12.6 0.1 0.11 11.1 0.1 1.6 1 1 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase CysG_dimeriser PF10414.9 ABX12407.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region IlvN PF07991.12 ABX12407.1 - 0.08 12.5 1.0 0.13 11.8 1.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Hpr_kinase_N PF02603.16 ABX12407.1 - 0.4 10.7 5.1 0.69 10.0 1.0 2.7 2 1 1 3 3 3 0 HPr Serine kinase N terminus AsnC_trans_reg2 PF17805.1 ABX12408.1 - 2.4e-53 178.2 0.0 7.2e-30 103.0 0.0 2.6 2 0 0 2 2 2 2 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 ABX12408.1 - 3.7e-05 23.5 0.0 0.0012 18.6 0.0 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 ABX12408.1 - 0.034 14.1 0.1 32 4.6 0.0 3.7 4 0 0 4 4 4 0 Lrp/AsnC ligand binding domain Muted PF14942.6 ABX12408.1 - 0.091 13.1 4.6 0.12 12.7 1.5 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein zf-B_box PF00643.24 ABX12409.1 - 0.011 15.9 2.9 0.017 15.3 2.9 1.3 1 0 0 1 1 1 0 B-box zinc finger C5HCH PF17982.1 ABX12409.1 - 0.11 12.6 4.0 0.13 12.5 2.6 1.7 1 1 1 2 2 2 0 NSD Cys-His rich domain Gmx_para_CXXCG PF09535.10 ABX12409.1 - 0.11 11.7 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) PADR1 PF08063.12 ABX12409.1 - 0.25 11.1 3.5 0.48 10.2 3.5 1.4 1 0 0 1 1 1 0 PADR1 (NUC008) domain Aldo_ket_red PF00248.21 ABX12410.1 - 2e-55 188.1 0.1 2.2e-55 187.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ECH_2 PF16113.5 ABX12410.1 - 0.031 13.8 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Chlor_dismutase PF06778.12 ABX12411.1 - 1.3e-55 188.1 0.0 1.6e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Chlorite dismutase ABC_tran PF00005.27 ABX12412.1 - 2.2e-20 73.5 0.0 3.2e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ABX12412.1 - 8.3e-11 41.7 0.4 6.3e-06 25.8 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ABX12412.1 - 1.9e-09 37.7 0.1 0.00013 21.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABX12412.1 - 0.00057 19.6 0.5 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ABX12412.1 - 0.0013 18.3 0.0 0.021 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ABX12412.1 - 0.0014 18.8 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ABX12412.1 - 0.0076 16.7 0.3 0.22 11.9 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ABX12412.1 - 0.0082 16.5 0.0 0.018 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 ABX12412.1 - 0.012 15.2 0.1 0.032 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ABX12412.1 - 0.017 15.7 0.1 0.21 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ABX12412.1 - 0.027 15.0 1.0 0.057 13.9 0.2 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ABX12412.1 - 0.028 14.2 0.0 0.48 10.1 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 ABX12412.1 - 0.031 13.0 0.5 1.7 7.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 ABX12412.1 - 0.037 14.3 0.1 0.11 12.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ABX12412.1 - 0.041 13.6 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABX12412.1 - 0.045 14.0 0.0 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ABX12412.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ABX12412.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 ABX12412.1 - 0.095 12.6 1.2 0.42 10.5 0.0 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 ABX12412.1 - 0.1 13.0 0.1 0.55 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ABX12412.1 - 0.16 12.4 0.0 0.44 11.0 0.0 1.7 2 0 0 2 2 2 0 RNA helicase TFIIB PF00382.19 ABX12413.1 - 2.2e-23 82.1 0.7 7.4e-11 41.9 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ABX12413.1 - 6.6e-10 38.3 1.3 6.6e-10 38.3 1.3 1.9 2 0 0 2 2 2 1 TFIIB zinc-binding RPA_interact_C PF14768.6 ABX12413.1 - 0.00051 20.5 0.4 0.032 14.8 0.1 2.8 2 1 0 2 2 2 1 Replication protein A interacting C-terminal DUF2318 PF10080.9 ABX12413.1 - 0.21 11.7 3.4 8 6.6 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) OrfB_Zn_ribbon PF07282.11 ABX12413.1 - 0.24 11.4 2.1 0.24 11.4 0.5 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 ABX12413.1 - 0.39 10.8 2.9 0.59 10.2 0.6 2.2 2 0 0 2 2 2 0 Double zinc ribbon Auto_anti-p27 PF06677.12 ABX12413.1 - 0.51 10.5 4.2 0.2 11.8 0.9 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) UPF0547 PF10571.9 ABX12413.1 - 2.7 8.2 8.9 1.3 9.2 4.1 2.6 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 Spt4 PF06093.13 ABX12413.1 - 2.7 8.2 6.6 1.8 8.7 0.3 3.2 2 2 1 3 3 3 0 Spt4/RpoE2 zinc finger Gar1 PF04410.14 ABX12414.1 - 5.4e-06 26.3 0.1 8e-06 25.7 0.1 1.4 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region SRP19 PF01922.17 ABX12415.1 - 6.2e-13 49.5 0.0 8.7e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein Nif11 PF07862.11 ABX12415.1 - 0.063 13.6 0.0 0.086 13.2 0.0 1.3 1 0 0 1 1 1 0 Nif11 domain Ribosomal_S8e PF01201.22 ABX12416.1 - 1.3e-19 70.8 7.0 1.5e-19 70.5 7.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMC_ScpB PF04079.16 ABX12417.1 - 8.5e-36 123.0 0.6 1e-35 122.7 0.6 1.1 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB TBPIP PF07106.13 ABX12417.1 - 0.049 13.6 0.4 16 5.5 0.0 3.2 2 2 0 2 2 2 0 TBPIP/Hop2 winged helix domain PadR PF03551.14 ABX12417.1 - 0.063 13.2 0.2 0.4 10.7 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family SMC_ScpA PF02616.14 ABX12418.1 - 4.2e-07 30.1 0.9 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 2 Segregation and condensation protein ScpA ADH_N PF08240.12 ABX12419.1 - 5.4e-34 116.4 0.3 8.8e-34 115.7 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABX12419.1 - 3.4e-27 95.0 0.2 5.5e-27 94.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABX12419.1 - 4.7e-11 43.9 0.0 7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABX12419.1 - 1.2e-07 31.4 0.1 4e-07 29.7 0.1 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ABX12419.1 - 0.0007 18.9 0.5 0.0011 18.4 0.5 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 ABX12419.1 - 0.016 14.8 0.5 0.024 14.2 0.5 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglD_N PF17836.1 ABX12419.1 - 0.021 15.4 0.3 0.044 14.4 0.3 1.6 1 0 0 1 1 1 0 PglD N-terminal domain TrkA_N PF02254.18 ABX12419.1 - 0.031 14.6 0.1 0.071 13.4 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Urocanase PF01175.18 ABX12419.1 - 0.048 13.3 0.1 0.082 12.5 0.1 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain NAD_binding_2 PF03446.15 ABX12419.1 - 0.093 12.9 0.2 0.16 12.1 0.2 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_16 PF10294.9 ABX12419.1 - 0.15 11.8 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase VitK2_biosynth PF02621.14 ABX12420.1 - 1.2e-58 198.7 0.0 1.7e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 Menaquinone biosynthesis CxxCxxCC PF03692.15 ABX12421.1 - 9.3e-10 39.1 1.7 2.1e-09 37.9 1.6 1.7 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain eIF-1a PF01176.19 ABX12422.1 - 2.2e-18 65.8 1.0 3.1e-18 65.3 1.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myosin_N PF02736.19 ABX12422.1 - 0.16 11.8 0.6 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain CSD PF00313.22 ABX12423.1 - 1.4e-20 72.9 3.0 1.8e-20 72.6 3.0 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ABX12423.1 - 2.4e-06 27.1 1.1 2.5e-06 27.1 1.1 1.1 1 0 0 1 1 1 1 Ribonuclease B OB domain MazE_antitoxin PF04014.18 ABX12423.1 - 0.12 12.4 0.9 0.29 11.1 0.9 1.8 1 1 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin Pico_P1A PF02226.16 ABX12424.1 - 0.084 12.9 1.0 13 5.9 0.6 2.4 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) eIF-5a PF01287.20 ABX12425.1 - 1.4e-07 31.5 3.1 1.9e-07 31.1 3.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 ABX12425.1 - 0.0034 17.4 0.1 0.051 13.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 ABX12425.1 - 0.06 13.4 1.2 0.19 11.8 1.2 1.8 1 1 0 1 1 1 0 Elongation factor P (EF-P) OB domain DUF2866 PF11065.8 ABX12425.1 - 0.09 12.8 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) ECD PF18432.1 ABX12425.1 - 0.5 10.3 2.5 4.7 7.2 0.1 2.5 2 1 1 3 3 3 0 Extracellular Cadherin domain Diphthami_syn_2 PF01902.17 ABX12426.1 - 1.1e-58 198.4 0.0 1.2e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Diphthamide synthase QueC PF06508.13 ABX12426.1 - 0.00042 19.9 0.0 0.0013 18.2 0.0 1.9 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ABX12426.1 - 0.021 13.6 0.0 0.051 12.4 0.0 1.6 2 0 0 2 2 2 0 tRNA methyl transferase Asn_synthase PF00733.21 ABX12426.1 - 0.024 14.3 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase THB PF18362.1 ABX12426.1 - 0.15 11.7 0.1 0.57 9.8 0.0 1.9 2 0 0 2 2 2 0 Tri-helix bundle domain SRP54 PF00448.22 ABX12427.1 - 1.9e-69 233.3 0.3 3.8e-69 232.3 0.3 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 ABX12427.1 - 6e-27 94.2 3.0 6e-27 94.2 3.0 2.8 4 0 0 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.19 ABX12427.1 - 1.9e-17 63.3 3.5 2.2e-17 63.0 1.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 ABX12427.1 - 1.5e-05 25.1 0.0 3.7e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.9 ABX12427.1 - 4.6e-05 23.2 0.9 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 ABX12427.1 - 6.3e-05 22.1 0.5 0.00043 19.4 0.5 2.3 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 ABX12427.1 - 0.00021 21.8 0.5 0.0015 19.1 0.5 2.6 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 ABX12427.1 - 0.00028 20.4 0.1 0.00054 19.5 0.1 1.5 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MobB PF03205.14 ABX12427.1 - 0.0005 20.0 0.3 0.0013 18.6 0.3 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 ABX12427.1 - 0.00079 19.8 0.0 0.0042 17.5 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABX12427.1 - 0.00081 19.7 0.1 0.0028 17.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.20 ABX12427.1 - 0.001 19.0 0.8 0.0027 17.6 0.1 2.1 3 0 0 3 3 1 1 Adenylylsulphate kinase 6PF2K PF01591.18 ABX12427.1 - 0.001 18.4 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase KTI12 PF08433.10 ABX12427.1 - 0.0013 18.3 0.1 0.0036 16.8 0.1 1.7 1 0 0 1 1 1 1 Chromatin associated protein KTI12 cobW PF02492.19 ABX12427.1 - 0.0014 18.2 2.0 0.0097 15.5 2.0 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 ABX12427.1 - 0.0016 17.7 0.0 0.024 13.8 0.0 2.3 1 1 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.12 ABX12427.1 - 0.0022 17.3 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 ABX12427.1 - 0.0031 18.0 0.3 0.0031 18.0 0.3 2.8 3 1 0 3 3 2 1 AAA domain AAA_31 PF13614.6 ABX12427.1 - 0.0032 17.4 1.4 0.011 15.6 0.4 2.2 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ABX12427.1 - 0.0037 17.3 0.4 0.017 15.2 0.4 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 ABX12427.1 - 0.009 15.7 0.4 0.03 14.0 0.4 1.8 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 ABX12427.1 - 0.009 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABX12427.1 - 0.0099 16.3 0.1 0.026 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 ABX12427.1 - 0.011 15.7 1.0 0.011 15.7 1.0 2.1 2 1 0 2 2 1 0 NTPase AAA_24 PF13479.6 ABX12427.1 - 0.013 15.2 1.1 0.03 14.0 0.4 2.1 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ABX12427.1 - 0.013 15.5 0.1 0.042 13.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 ABX12427.1 - 0.015 14.8 0.5 0.53 9.7 0.2 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_26 PF13500.6 ABX12427.1 - 0.019 14.8 0.1 6.7 6.5 1.1 2.8 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 ABX12427.1 - 0.024 15.2 0.8 0.068 13.7 0.1 2.1 2 1 0 2 2 2 0 ABC transporter MipZ PF09140.11 ABX12427.1 - 0.027 13.7 1.0 2.8 7.2 1.0 2.3 1 1 0 1 1 1 0 ATPase MipZ Arf PF00025.21 ABX12427.1 - 0.029 13.8 0.0 0.089 12.2 0.0 1.8 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_30 PF13604.6 ABX12427.1 - 0.032 14.0 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 ABX12427.1 - 0.038 13.8 0.2 0.083 12.7 0.2 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein LpxK PF02606.14 ABX12427.1 - 0.055 12.6 0.1 0.093 11.8 0.1 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase LytR_C PF13399.6 ABX12427.1 - 0.063 14.3 0.0 0.18 12.8 0.0 1.9 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator AAA_25 PF13481.6 ABX12427.1 - 0.083 12.5 1.5 0.38 10.3 1.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABX12427.1 - 0.093 13.0 0.3 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 AAA domain SpoVIF PF14069.6 ABX12427.1 - 0.28 11.0 3.2 0.4 10.5 1.2 2.3 2 0 0 2 2 2 0 Stage VI sporulation protein F IstB_IS21 PF01695.17 ABX12427.1 - 0.37 10.5 1.4 1.2 8.8 0.1 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein THUMP PF02926.17 ABX12428.1 - 8.3e-07 29.2 0.0 2.1e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 THUMP domain Ribosomal_S27 PF01599.19 ABX12430.1 - 2.7e-19 69.0 6.0 3.2e-19 68.8 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27a Ribosomal_L37e PF01907.19 ABX12430.1 - 0.00062 19.9 2.0 0.00078 19.6 2.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e Ephrin_rec_like PF07699.13 ABX12430.1 - 0.00089 19.0 1.2 0.001 18.8 1.2 1.2 1 0 0 1 1 1 1 Putative ephrin-receptor like DUF1451 PF07295.11 ABX12430.1 - 0.0013 18.7 0.8 0.0014 18.7 0.8 1.0 1 0 0 1 1 1 1 Zinc-ribbon containing domain NCD3G PF07562.14 ABX12430.1 - 0.029 14.3 1.4 0.038 14.0 1.4 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR Nudix_N_2 PF14803.6 ABX12430.1 - 0.03 14.3 4.2 0.8 9.7 4.1 2.2 1 1 1 2 2 2 0 Nudix N-terminal Whib PF02467.16 ABX12430.1 - 0.043 14.4 0.4 0.49 11.0 0.0 2.0 1 1 1 2 2 2 0 Transcription factor WhiB HypA PF01155.19 ABX12430.1 - 0.068 13.2 0.6 0.069 13.2 0.6 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 ABX12430.1 - 0.096 12.4 3.0 0.96 9.2 0.2 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 ABX12430.1 - 0.13 11.7 3.9 4.7 6.8 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.6 ABX12430.1 - 0.29 11.3 2.8 0.39 10.9 0.1 1.9 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf_UBZ PF18439.1 ABX12430.1 - 5.4 6.7 7.8 2.3 7.9 1.6 2.5 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger YhfH PF14149.6 ABX12430.1 - 6.4 6.8 8.3 20 5.3 7.9 1.9 1 1 1 2 2 2 0 YhfH-like protein Ribosomal_S24e PF01282.19 ABX12431.1 - 1.2e-05 25.1 0.1 1.9e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e DUF309 PF03745.14 ABX12432.1 - 1.7e-16 59.6 0.2 2.8e-16 58.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF309) UL42 PF17638.2 ABX12432.1 - 0.21 11.6 0.1 21 5.1 0.0 2.2 1 1 1 2 2 2 0 HCMV UL42 PhosphMutase PF10143.9 ABX12433.1 - 1.6e-43 148.5 0.0 3.4e-43 147.5 0.0 1.5 2 0 0 2 2 2 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 ABX12433.1 - 1e-27 97.1 0.8 1.2e-27 96.8 0.8 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 ABX12433.1 - 0.00099 18.8 0.0 0.002 17.8 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase mCpol PF18182.1 ABX12433.1 - 0.3 11.4 2.2 12 6.3 0.1 3.7 4 0 0 4 4 4 0 minimal CRISPR polymerase domain GalP_UDP_transf PF01087.22 ABX12434.1 - 4.1e-09 37.1 0.1 1.1e-08 35.7 0.0 1.8 3 0 0 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.23 ABX12434.1 - 0.00027 21.6 0.0 0.001 19.8 0.0 1.9 2 0 0 2 2 2 1 HIT domain DUF4921 PF16268.5 ABX12434.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4921) GalP_UDP_tr_C PF02744.17 ABX12434.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4931 PF16285.5 ABX12434.1 - 0.02 14.2 0.1 0.11 11.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4931) DUF2189 PF09955.9 ABX12435.1 - 0.00022 21.5 0.2 0.00041 20.6 0.2 1.4 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2189) DUF2207 PF09972.9 ABX12435.1 - 0.93 8.2 4.6 9.4 4.9 4.6 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Acetyltransf_1 PF00583.25 ABX12436.1 - 1.4e-18 67.2 0.0 1.6e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ABX12436.1 - 6e-17 61.8 0.1 7.2e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABX12436.1 - 1.9e-13 50.6 0.1 2.7e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABX12436.1 - 0.00049 20.2 0.0 0.00063 19.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ABX12436.1 - 0.002 18.2 0.0 0.0038 17.3 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase EF-hand_7 PF13499.6 ABX12436.1 - 0.066 13.7 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF4869 PF16163.5 ABX12436.1 - 0.079 12.7 0.6 0.17 11.6 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4869) NTP_transferase PF00483.23 ABX12437.1 - 1.6e-43 149.1 0.2 1.8e-43 148.9 0.2 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ABX12437.1 - 4.1e-09 37.0 0.0 4.8e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 ABX12437.1 - 0.028 14.2 0.0 0.072 12.8 0.0 1.6 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 ABX12437.1 - 0.05 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Phos_pyr_kin PF08543.12 ABX12438.1 - 2.6e-73 246.4 4.0 5.6e-73 245.3 2.7 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase ThiP_synth PF10120.9 ABX12438.1 - 6.1e-55 185.3 0.1 2.5e-54 183.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine-phosphate synthase PfkB PF00294.24 ABX12438.1 - 3.9e-10 39.5 0.1 8.8e-10 38.4 0.1 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 ABX12438.1 - 0.00017 21.2 0.2 0.00049 19.7 0.1 1.7 1 1 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 ABX12438.1 - 0.00062 19.2 0.7 0.00097 18.6 0.7 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family LMBR1 PF04791.16 ABX12438.1 - 0.035 13.0 0.9 0.055 12.4 0.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ThiC_Rad_SAM PF01964.18 ABX12439.1 - 3.5e-173 576.2 1.0 4.1e-173 576.0 1.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family DUF3006 PF11213.8 ABX12439.1 - 0.1 12.8 2.1 4.7 7.5 0.1 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF3006) NUDIX PF00293.28 ABX12440.1 - 4.1e-13 49.5 0.1 4.5e-13 49.4 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain PDH PF02153.17 ABX12441.1 - 3.2e-23 82.1 0.3 3.7e-23 81.8 0.3 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 ABX12441.1 - 3.2e-07 30.6 0.2 1.6e-06 28.4 0.0 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ABX12441.1 - 5.5e-06 26.4 0.7 8.1e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ABX12441.1 - 4.5e-05 22.9 0.0 8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ABX12441.1 - 5.4e-05 23.7 0.4 0.00049 20.6 0.0 2.8 2 2 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 ABX12441.1 - 0.00041 20.4 1.9 2.1 8.3 0.0 3.3 2 1 1 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.12 ABX12441.1 - 0.00057 19.5 0.1 0.0029 17.2 0.0 2.0 1 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox_2 PF07992.14 ABX12441.1 - 0.002 17.4 0.3 0.005 16.1 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 ABX12441.1 - 0.0055 16.2 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DpaA_N PF16924.5 ABX12441.1 - 0.0061 16.6 0.1 0.023 14.8 0.0 2.1 2 2 0 2 2 2 1 Dipicolinate synthase subunit A N-terminal domain CoA_binding_2 PF13380.6 ABX12441.1 - 0.024 15.1 0.0 0.1 13.1 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain DUF2529 PF10740.9 ABX12441.1 - 0.028 14.0 0.1 0.2 11.3 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2529) DUF1392 PF07154.11 ABX12441.1 - 0.049 13.8 0.1 0.13 12.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1392) Semialdhyde_dh PF01118.24 ABX12441.1 - 0.054 13.9 0.0 0.92 10.0 0.0 2.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 ABX12441.1 - 0.06 13.4 2.2 3.7 7.6 0.1 3.4 2 2 2 4 4 4 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 ABX12441.1 - 0.13 11.7 1.2 2.3 7.6 0.0 2.4 2 1 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.13 ABX12441.1 - 0.17 11.4 1.7 0.43 10.1 0.2 2.4 3 0 0 3 3 3 0 NmrA-like family Aminotran_1_2 PF00155.21 ABX12442.1 - 4.7e-61 207.0 0.1 6.1e-61 206.6 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CM_2 PF01817.21 ABX12442.1 - 1.8e-13 50.6 1.5 3.9e-12 46.3 0.8 3.1 3 0 0 3 3 3 1 Chorismate mutase type II Aminotran_5 PF00266.19 ABX12442.1 - 2.4e-08 33.4 0.0 5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ABX12442.1 - 2.7e-06 26.2 0.0 4.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ABX12442.1 - 0.00019 20.9 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 ABX12442.1 - 0.0002 20.4 2.4 0.0007 18.6 0.4 2.5 3 0 0 3 3 3 1 Allinase LppX_LprAFG PF07161.13 ABX12442.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 LppX_LprAFG lipoprotein Beta_elim_lyase PF01212.21 ABX12442.1 - 0.008 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase PET122 PF05476.11 ABX12442.1 - 0.05 12.9 0.5 0.098 11.9 0.0 1.8 2 0 0 2 2 2 0 PET122 Chorismate_synt PF01264.21 ABX12443.1 - 2.6e-137 456.9 0.9 3e-137 456.7 0.9 1.0 1 0 0 1 1 1 1 Chorismate synthase EPSP_synthase PF00275.20 ABX12444.1 - 8.2e-99 331.1 0.0 1e-98 330.8 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) TubC_N PF18563.1 ABX12444.1 - 0.11 12.5 0.3 16 5.6 0.0 3.1 3 0 0 3 3 3 0 TubC N-terminal docking domain GHMP_kinases_N PF00288.26 ABX12445.1 - 2.3e-09 37.4 0.5 5e-09 36.3 0.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ABX12445.1 - 1.9e-05 24.9 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DUF3560 PF12083.8 ABX12445.1 - 0.092 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Shikimate_dh_N PF08501.11 ABX12446.1 - 1.4e-28 98.9 0.0 4.9e-28 97.2 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ABX12446.1 - 3e-13 49.3 0.5 4.7e-13 48.7 0.5 1.3 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 ABX12446.1 - 2e-12 47.4 0.4 3.6e-12 46.5 0.4 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ABX12446.1 - 3.8e-06 27.2 0.2 5.3e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 ABX12446.1 - 0.0044 17.6 1.0 0.0083 16.7 1.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GARS_N PF02844.15 ABX12446.1 - 0.011 16.6 0.4 0.03 15.1 0.2 1.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain CBAH PF02275.18 ABX12446.1 - 0.025 14.3 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family NAD_binding_7 PF13241.6 ABX12446.1 - 0.028 14.9 0.1 0.057 13.9 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DHquinase_I PF01487.15 ABX12447.1 - 1e-54 186.2 0.0 1.1e-54 186.1 0.0 1.0 1 0 0 1 1 1 1 Type I 3-dehydroquinase DHQS PF01959.16 ABX12448.1 - 1.6e-105 352.9 0.3 1.9e-105 352.7 0.3 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase II CppA_N PF14506.6 ABX12448.1 - 0.044 13.8 0.1 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 CppA N-terminal Med7 PF05983.11 ABX12448.1 - 0.053 13.6 0.1 0.086 12.9 0.1 1.2 1 0 0 1 1 1 0 MED7 protein Glyco_transf_41 PF13844.6 ABX12448.1 - 0.12 10.7 0.0 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 41 DeoC PF01791.9 ABX12449.1 - 1.4e-48 165.5 0.0 1.7e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase DUF561 PF04481.12 ABX12449.1 - 0.15 11.2 0.1 0.28 10.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Radical_SAM PF04055.21 ABX12450.1 - 3e-19 70.0 0.0 4.4e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UbiD PF01977.16 ABX12451.1 - 1.4e-153 511.6 0.1 1.7e-153 511.3 0.1 1.1 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF4751 PF15942.5 ABX12451.1 - 0.29 11.1 1.2 0.93 9.4 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4751) ANF_receptor PF01094.28 ABX12452.1 - 2.5e-23 82.7 0.1 3.5e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ABX12452.1 - 3.7e-17 63.0 0.0 4.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein HATPase_c PF02518.26 ABX12452.1 - 8.4e-13 48.8 0.1 1.5e-12 48.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Trypan_PARP PF05887.11 ABX12452.1 - 1.1e-08 35.2 174.2 0.0033 17.4 58.3 3.5 1 1 2 3 3 3 3 Procyclic acidic repetitive protein (PARP) HATPase_c_3 PF13589.6 ABX12452.1 - 0.014 15.2 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peripla_BP_5 PF13433.6 ABX12452.1 - 0.028 13.4 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain Sigma_reg_N PF13800.6 ABX12452.1 - 0.12 12.7 1.2 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF2748 PF10871.8 ABX12453.1 - 0.11 11.1 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) ABC_tran_CTD PF16326.5 ABX12454.1 - 0.0059 16.8 2.6 0.0088 16.3 1.9 1.7 2 0 0 2 2 2 1 ABC transporter C-terminal domain CLZ PF16526.5 ABX12454.1 - 0.04 14.3 0.3 0.076 13.4 0.3 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PilJ PF13675.6 ABX12454.1 - 0.041 13.9 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term HBM PF16591.5 ABX12454.1 - 0.091 12.2 0.1 0.091 12.2 0.1 2.1 3 0 0 3 3 3 0 Helical bimodular sensor domain Striatin PF08232.12 ABX12454.1 - 0.18 12.4 3.5 0.29 11.7 3.5 1.4 1 0 0 1 1 1 0 Striatin family M PF02370.16 ABX12454.1 - 0.65 10.7 3.8 2.9 8.7 3.8 2.2 1 0 0 1 1 1 0 M protein repeat Swi5 PF07061.11 ABX12454.1 - 0.84 9.8 2.9 1.8 8.7 2.9 1.6 1 1 0 1 1 1 0 Swi5 SRP72 PF08492.12 ABX12455.1 - 0.027 14.9 0.9 0.027 14.9 0.9 3.5 3 1 0 3 3 3 0 SRP72 RNA-binding domain M PF02370.16 ABX12455.1 - 0.03 14.8 2.2 0.03 14.8 2.2 3.3 3 1 0 3 3 3 0 M protein repeat SF-assemblin PF06705.11 ABX12455.1 - 0.089 12.1 4.0 0.15 11.4 0.4 2.0 2 0 0 2 2 2 0 SF-assemblin/beta giardin DUF4407 PF14362.6 ABX12455.1 - 0.22 10.8 9.1 0.3 10.4 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 ABX12455.1 - 0.23 11.2 0.2 0.23 11.2 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator PLC-beta_C PF08703.10 ABX12455.1 - 1.3 8.9 9.5 0.55 10.2 5.0 2.0 2 0 0 2 2 2 0 PLC-beta C terminal bZIP_1 PF00170.21 ABX12455.1 - 2.5 8.3 9.0 1.6 8.9 0.8 2.7 2 1 1 3 3 3 0 bZIP transcription factor HSCB_C PF07743.13 ABX12455.1 - 7.3 7.2 12.3 10 6.7 6.0 2.4 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Atg14 PF10186.9 ABX12455.1 - 8.7 5.3 6.4 4.4 6.3 0.2 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AhpC-TSA PF00578.21 ABX12456.1 - 4e-40 136.6 0.2 4.7e-40 136.4 0.2 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ABX12456.1 - 8e-29 100.2 0.1 9.5e-29 100.0 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 ABX12456.1 - 2.1e-08 34.3 0.0 3.3e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 ABX12456.1 - 6.3e-08 32.4 0.0 7.2e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) SCO1-SenC PF02630.14 ABX12456.1 - 4.5e-05 23.4 0.1 6.8e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 ABX12456.1 - 0.00065 20.0 0.0 0.0011 19.2 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin-like GSHPx PF00255.19 ABX12456.1 - 0.092 12.3 0.0 0.2 11.2 0.0 1.6 1 1 0 1 1 1 0 Glutathione peroxidase MIP PF00230.20 ABX12457.1 - 2.4e-50 171.3 18.7 3.3e-50 170.9 18.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein Mo25 PF08569.11 ABX12458.1 - 0.024 14.0 7.3 0.028 13.8 6.8 1.3 1 1 0 1 1 1 0 Mo25-like MutS_III PF05192.18 ABX12458.1 - 0.032 14.5 3.3 0.037 14.3 3.3 1.1 1 0 0 1 1 1 0 MutS domain III DUF489 PF04356.12 ABX12458.1 - 0.036 14.1 3.3 0.047 13.7 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF3385 PF11865.8 ABX12458.1 - 0.045 13.7 2.6 0.054 13.4 2.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) DUF1840 PF08895.11 ABX12458.1 - 0.06 13.7 2.6 0.14 12.5 2.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) RPN5_C PF18098.1 ABX12458.1 - 0.11 12.6 0.2 0.11 12.6 0.2 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain Casc1_N PF15927.5 ABX12458.1 - 0.17 11.5 8.6 0.81 9.3 8.6 1.8 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus ECH_1 PF00378.20 ABX12458.1 - 0.35 10.1 5.0 0.43 9.8 1.3 2.0 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase FemAB PF02388.16 ABX12458.1 - 0.36 9.6 7.3 0.15 10.9 4.7 1.6 1 1 1 2 2 2 0 FemAB family DUF4363 PF14276.6 ABX12458.1 - 0.41 10.8 9.7 4.4 7.5 0.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) DUF5339 PF17274.2 ABX12458.1 - 10 7.1 10.7 1.9 9.4 4.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5339) Methyltransf_32 PF13679.6 ABX12459.1 - 0.036 14.0 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 4HBT PF03061.22 ABX12460.1 - 0.00025 21.3 0.0 0.00037 20.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Methyltransf_31 PF13847.6 ABX12461.1 - 4.8e-16 58.9 0.0 6.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX12461.1 - 2.2e-13 50.7 0.0 3.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABX12461.1 - 6.3e-08 33.3 0.0 1.2e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABX12461.1 - 1e-07 32.5 0.0 1.8e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ABX12461.1 - 4.2e-07 30.1 0.0 5.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ABX12461.1 - 7.4e-07 28.8 0.1 1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 ABX12461.1 - 2.7e-06 26.9 0.1 3.7e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ABX12461.1 - 7.7e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ABX12461.1 - 0.00066 19.3 0.0 0.0014 18.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ABX12461.1 - 0.026 14.0 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Rsm22 PF09243.10 ABX12461.1 - 0.03 13.6 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_33 PF10017.9 ABX12461.1 - 0.036 13.2 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent PCMT PF01135.19 ABX12461.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CBS PF00571.28 ABX12464.1 - 2.4e-26 91.9 0.5 9.1e-13 48.4 0.2 2.1 2 0 0 2 2 2 2 CBS domain CCB1 PF12046.8 ABX12465.1 - 0.059 12.7 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B Polysacc_synt_C PF14667.6 ABX12465.1 - 0.35 10.9 9.8 1 9.5 2.2 2.3 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Asp4 PF16996.5 ABX12465.1 - 1.1 9.1 5.4 1 9.2 0.9 2.3 1 1 1 2 2 2 0 Accessory secretory protein Sec Asp4 Adenine_glyco PF03352.13 ABX12466.1 - 5.1e-79 264.2 0.2 6.2e-79 263.9 0.2 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase Pro_CA PF00484.19 ABX12467.1 - 0.0019 18.5 0.6 0.0052 17.1 0.6 1.7 1 1 0 1 1 1 1 Carbonic anhydrase DUF2483 PF10656.9 ABX12467.1 - 0.027 14.7 0.3 0.057 13.6 0.1 1.6 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2483) MFS_1 PF07690.16 ABX12468.1 - 0.0098 14.9 44.5 0.26 10.2 17.2 3.4 2 2 0 2 2 2 2 Major Facilitator Superfamily Ferritin PF00210.24 ABX12469.1 - 2.8e-40 137.5 1.3 3.3e-40 137.3 1.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 ABX12469.1 - 2.6e-05 24.7 1.0 3.4e-05 24.2 1.0 1.1 1 0 0 1 1 1 1 Rubrerythrin DUF1477 PF07346.11 ABX12469.1 - 0.085 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) DUF3990 PF13151.6 ABX12471.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3990) LRR_9 PF14580.6 ABX12471.1 - 0.084 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat Putative_PNPOx PF01243.20 ABX12472.1 - 6.9e-15 55.0 0.0 8.6e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.12 ABX12472.1 - 0.029 14.2 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Pyrid_ox_like PF16242.5 ABX12472.1 - 0.039 13.5 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like MscS_porin PF12795.7 ABX12473.1 - 0.0013 18.4 32.1 0.031 13.8 13.2 3.0 2 1 1 3 3 3 2 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 ABX12473.1 - 0.0017 18.5 51.3 0.66 10.0 14.3 3.4 2 1 1 3 3 3 3 TPR/MLP1/MLP2-like protein WEMBL PF05701.11 ABX12473.1 - 0.017 13.8 42.9 0.21 10.2 2.5 3.2 2 1 0 2 2 2 0 Weak chloroplast movement under blue light Spc7 PF08317.11 ABX12473.1 - 0.029 13.2 54.8 0.74 8.6 17.6 3.0 1 1 1 3 3 3 0 Spc7 kinetochore protein IFT57 PF10498.9 ABX12473.1 - 0.038 13.0 40.6 0.085 11.8 7.4 3.0 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 WXG100 PF06013.12 ABX12473.1 - 0.04 14.1 13.5 0.97 9.7 0.3 4.3 3 2 1 4 4 4 0 Proteins of 100 residues with WXG DUF745 PF05335.13 ABX12473.1 - 0.22 11.2 30.1 1 9.1 11.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF745) HIP1_clath_bdg PF16515.5 ABX12473.1 - 0.24 12.0 51.3 0.34 11.6 7.1 4.1 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5593 PF18007.1 ABX12473.1 - 0.43 11.3 3.5 5 7.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5593) LPP PF04728.13 ABX12473.1 - 1.1 9.7 14.4 1.8 9.0 1.0 3.8 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF948 PF06103.11 ABX12473.1 - 1.3 9.3 17.1 0.23 11.8 2.2 3.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) EzrA PF06160.12 ABX12473.1 - 1.4 7.0 46.2 1.7 6.7 35.9 2.8 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Com_YlbF PF06133.11 ABX12473.1 - 1.4 9.5 43.8 1.4 9.6 16.2 3.7 2 1 1 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA YvbH_ext PF11724.8 ABX12473.1 - 1.7 9.0 7.7 2 8.8 0.9 3.6 2 1 1 3 3 3 0 YvbH-like oligomerisation region DUF4201 PF13870.6 ABX12473.1 - 1.8 8.2 45.4 0.73 9.5 4.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 ABX12473.1 - 2.6 8.6 14.6 5.5 7.5 2.0 3.8 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 ABX12473.1 - 2.7 8.0 29.9 2.9 7.9 6.0 3.2 2 1 1 3 3 3 0 Laminin Domain II DUF4407 PF14362.6 ABX12473.1 - 3.3 7.0 28.4 3.8 6.8 11.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DLP_helical PF18709.1 ABX12473.1 - 3.8 6.6 34.7 1.4 8.0 2.2 3.6 1 1 3 4 4 4 0 Dynamin-like helical domain ATG16 PF08614.11 ABX12473.1 - 4 7.6 42.6 13 5.9 9.8 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 ABX12473.1 - 5.4 4.4 39.4 1.8 6.0 28.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) HrpB7 PF09486.10 ABX12473.1 - 5.9 7.3 20.8 9.7 6.6 0.7 3.7 1 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) She9_MDM33 PF05546.11 ABX12473.1 - 6.9 6.4 29.9 0.071 12.9 2.3 3.3 1 1 0 3 3 3 0 She9 / Mdm33 family OSR1_C PF12202.8 ABX12473.1 - 7.4 6.9 17.7 0.21 11.8 0.6 3.6 3 1 0 3 3 3 0 Oxidative-stress-responsive kinase 1 C-terminal domain Fez1 PF06818.15 ABX12473.1 - 9.6 6.6 44.3 20 5.6 13.9 2.4 1 1 1 2 2 2 0 Fez1 tRNA-synt_1f PF01921.18 ABX12474.1 - 2e-107 359.2 0.1 4.3e-107 358.2 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (K) PolyA_pol_RNAbd PF12627.7 ABX12474.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Uricase PF01014.18 ABX12474.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Uricase Radical_SAM_C PF16199.5 ABX12475.1 - 1.2e-25 89.4 0.2 2.5e-25 88.3 0.2 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 ABX12475.1 - 1.1e-19 71.4 0.1 4.9e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 ABX12475.1 - 2.2e-08 34.3 0.1 6.2e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ABX12475.1 - 7.1e-06 26.0 0.1 2.7e-05 24.1 0.2 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF971 PF06155.12 ABX12475.1 - 0.11 13.2 0.0 0.31 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF971) HC2 PF07382.11 ABX12476.1 - 0.00027 21.1 39.5 0.00029 21.0 39.5 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Mt_ATP-synt_B PF05405.14 ABX12476.1 - 0.73 9.4 9.0 1.4 8.5 9.0 1.5 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) VSG_B PF13206.6 ABX12476.1 - 1 8.5 14.3 1.1 8.4 14.3 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain V_ATPase_I PF01496.19 ABX12476.1 - 8.2 4.2 9.9 9.2 4.0 9.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Na_H_Exchanger PF00999.21 ABX12477.1 - 2.2e-60 204.5 54.2 2.9e-60 204.1 54.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PspB PF06667.12 ABX12477.1 - 0.12 12.5 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Phage shock protein B AIRS_C PF02769.22 ABX12478.1 - 6.8e-24 84.8 0.0 1.3e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 ABX12478.1 - 5.5e-16 59.0 1.7 1.1e-15 58.0 1.7 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PAC2 PF09754.9 ABX12479.1 - 2.6e-38 132.2 0.0 2.9e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 PAC2 family HOIP-UBA PF16678.5 ABX12480.1 - 0.0055 16.7 1.0 0.023 14.7 0.4 2.3 2 0 0 2 2 2 1 HOIP UBA domain pair Cortex-I_coil PF09304.10 ABX12480.1 - 0.32 11.2 21.3 0.38 11.0 2.9 3.3 2 1 1 3 3 3 0 Cortexillin I, coiled coil DUF3150 PF11348.8 ABX12480.1 - 0.62 9.3 7.7 0.052 12.8 0.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3150) Arc_PepC_II PF06847.11 ABX12480.1 - 2.4 8.7 5.4 7.6 7.1 0.5 3.3 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II Cytochrom_C_2 PF01322.20 ABX12480.1 - 8.6 7.3 7.2 4.6 8.1 0.9 2.9 2 1 0 2 2 2 0 Cytochrome C' DUF4364 PF14277.6 ABX12481.1 - 0.0043 16.8 0.2 0.0076 16.0 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_45 PF14947.6 ABX12481.1 - 0.017 15.1 0.3 0.025 14.6 0.3 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix HMG-CoA_red PF00368.18 ABX12481.1 - 0.028 13.4 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase NotI PF12183.8 ABX12481.1 - 0.073 12.4 0.0 0.085 12.2 0.0 1.0 1 0 0 1 1 1 0 Restriction endonuclease NotI P-II PF00543.22 ABX12482.1 - 1.5e-09 38.4 0.3 2.3e-09 37.7 0.3 1.3 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II P-II PF00543.22 ABX12483.1 - 2.5e-13 50.5 0.7 3.1e-13 50.2 0.7 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II YidC_periplas PF14849.6 ABX12483.1 - 0.087 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 YidC periplasmic domain Ammonium_transp PF00909.21 ABX12484.1 - 9.8e-113 376.8 34.6 1.1e-112 376.7 34.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Na_Ca_ex PF01699.24 ABX12486.1 - 3.9e-43 147.0 35.9 4.8e-24 85.0 17.3 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PmbA_TldD PF01523.16 ABX12487.1 - 2.2e-46 159.0 0.6 3.2e-46 158.4 0.6 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Pyr_redox PF00070.27 ABX12487.1 - 0.037 14.6 1.2 1.1 9.9 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Radical_SAM PF04055.21 ABX12488.1 - 1.2e-20 74.5 1.6 1.3e-20 74.4 0.4 1.6 2 0 0 2 2 2 1 Radical SAM superfamily AP_endonuc_2 PF01261.24 ABX12488.1 - 0.0023 17.4 0.2 0.028 13.9 0.0 2.3 2 1 1 3 3 3 1 Xylose isomerase-like TIM barrel DUF5486 PF17588.2 ABX12488.1 - 0.12 12.3 0.2 8.7 6.3 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5486) Fer4_14 PF13394.6 ABX12488.1 - 0.67 10.1 3.2 0.44 10.7 0.1 2.3 3 0 0 3 3 3 0 4Fe-4S single cluster domain DUF2067 PF09840.9 ABX12488.1 - 0.95 9.0 4.8 3.8 7.1 0.1 3.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2067) Radical_SAM PF04055.21 ABX12489.1 - 2.1e-11 44.5 0.0 3.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Trypsin_2 PF13365.6 ABX12490.1 - 4.4e-34 118.6 0.5 1.3e-33 117.1 0.1 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 ABX12490.1 - 4.9e-12 46.0 0.3 1.1e-11 44.9 0.3 1.6 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 ABX12490.1 - 1.6e-11 44.5 0.0 3.4e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 ABX12490.1 - 1.3e-05 24.9 2.7 0.029 14.2 0.4 3.1 3 0 0 3 3 3 2 PDZ domain Peptidase_S29 PF02907.15 ABX12490.1 - 0.0041 16.9 0.1 0.013 15.2 0.1 1.9 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 ABX12490.1 - 0.0057 15.4 0.8 0.024 13.3 0.3 1.8 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S7 PF00949.21 ABX12490.1 - 0.043 13.6 0.4 0.077 12.8 0.4 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S32 PF05579.13 ABX12490.1 - 0.079 12.1 0.9 5.4 6.1 0.2 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 VirB8 PF04335.13 ABX12490.1 - 0.2 11.5 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 VirB8 protein Glycos_transf_2 PF00535.26 ABX12491.1 - 1.4e-27 96.5 0.0 2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ABX12491.1 - 1.9e-18 67.2 0.0 2.5e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ABX12491.1 - 1.1e-11 44.5 0.0 2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 ABX12491.1 - 2.9e-05 24.5 0.0 5.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 ABX12491.1 - 3.9e-05 23.3 0.0 5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ABX12491.1 - 0.001 19.0 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Polyketide_cyc2 PF10604.9 ABX12492.1 - 6.9e-12 45.8 0.0 7.6e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ABX12492.1 - 3.7e-08 33.7 0.1 5.3e-08 33.1 0.1 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport tRNA_bind PF01588.20 ABX12493.1 - 1.5e-21 76.3 0.0 1.9e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Putative tRNA binding domain TBP PF00352.21 ABX12494.1 - 8.3e-55 182.7 0.0 2.2e-27 94.8 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 ABX12494.1 - 6.5e-08 32.6 0.0 0.00046 20.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF1512 PF07431.12 ABX12495.1 - 1.2e-133 445.6 8.5 1.3e-133 445.4 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1512) Peptidase_M24 PF00557.24 ABX12497.1 - 3.6e-36 124.8 0.3 4.8e-36 124.4 0.3 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 HSR PF03172.13 ABX12497.1 - 0.03 14.5 0.0 7.3 6.8 0.0 2.3 2 0 0 2 2 2 0 HSR domain DZR PF12773.7 ABX12498.1 - 0.01 15.8 1.4 0.013 15.5 1.4 1.1 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 ABX12498.1 - 0.012 15.4 0.8 0.017 15.0 0.8 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 ABX12498.1 - 0.037 14.1 0.1 0.039 14.0 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PolC_DP2 PF03833.13 ABX12498.1 - 0.1 10.5 0.1 0.1 10.5 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 FHIPEP PF00771.20 ABX12498.1 - 0.13 10.7 0.0 0.13 10.7 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family CTV_P6 PF06706.11 ABX12498.1 - 0.29 10.9 5.4 0.4 10.4 5.4 1.2 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein TF_Zn_Ribbon PF08271.12 ABX12498.1 - 1.9 8.1 6.3 7.7 6.1 1.3 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding Phage_integrase PF00589.22 ABX12499.1 - 2.3e-07 30.8 1.2 1.8e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Phage integrase family AAA_23 PF13476.6 ABX12499.1 - 5.3 7.5 15.1 0.52 10.8 9.0 2.0 1 1 1 2 2 2 0 AAA domain zf-C2H2_2 PF12756.7 ABX12500.1 - 0.11 12.8 1.2 0.21 12.0 0.2 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Methylase_S PF01420.19 ABX12501.1 - 2.2e-27 96.3 20.6 7.5e-17 62.0 6.4 2.3 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain N6_Mtase PF02384.16 ABX12502.1 - 1e-100 337.0 1.1 1.4e-100 336.6 1.1 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 ABX12502.1 - 1.7e-23 83.7 2.4 1.7e-23 83.7 2.4 2.8 2 1 0 2 2 2 1 HsdM N-terminal domain UPF0020 PF01170.18 ABX12502.1 - 2.2e-06 27.5 0.0 6e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Macro PF01661.21 ABX12502.1 - 0.0017 18.4 0.0 0.092 12.8 0.0 2.5 2 0 0 2 2 2 1 Macro domain Methylase_S PF01420.19 ABX12503.1 - 6.2e-45 153.4 17.4 9.5e-32 110.5 2.9 2.2 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain DUF2443 PF10398.9 ABX12503.1 - 0.21 11.6 2.0 1.2 9.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) SWI2_SNF2 PF18766.1 ABX12504.1 - 2.4e-68 230.2 0.0 6.8e-68 228.7 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HSDR_N PF04313.14 ABX12504.1 - 2.7e-19 69.9 0.1 2.7e-19 69.9 0.1 2.4 2 1 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.15 ABX12504.1 - 3.9e-16 59.5 0.4 3.9e-16 59.5 0.4 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ABX12504.1 - 2e-05 24.5 0.1 0.0055 16.5 0.0 3.0 2 1 1 3 3 3 2 DEAD/DEAH box helicase PPDFL PF15060.6 ABX12504.1 - 0.079 13.5 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 Differentiation and proliferation regulator DUF45 PF01863.17 ABX12505.1 - 1.8e-37 129.4 6.3 6.4e-32 111.3 0.5 2.0 1 1 1 2 2 2 2 Protein of unknown function DUF45 WLM PF08325.10 ABX12505.1 - 0.00025 21.2 0.2 0.00025 21.2 0.2 1.9 2 1 0 2 2 2 1 WLM domain SprT-like PF10263.9 ABX12505.1 - 0.0048 16.7 0.6 0.008 16.0 0.6 1.7 1 1 0 1 1 1 1 SprT-like family UPF0113_N PF17833.1 ABX12505.1 - 0.023 15.3 0.4 0.045 14.3 0.4 1.5 1 0 0 1 1 1 0 UPF0113 Pre-PUA domain HTH_micro PF17007.5 ABX12505.1 - 0.043 12.6 4.6 0.049 12.5 4.6 1.1 1 0 0 1 1 1 0 HTH-like RuvC PF02075.17 ABX12505.1 - 0.043 13.7 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC N6_Mtase PF02384.16 ABX12506.1 - 3e-29 102.3 0.1 6e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase HSDR_N_2 PF13588.6 ABX12506.1 - 4.8e-23 81.3 0.2 1.1e-22 80.1 0.2 1.6 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) Methylase_S PF01420.19 ABX12506.1 - 3.2e-13 50.2 6.6 3.2e-13 50.2 6.6 2.2 2 0 0 2 2 2 1 Type I restriction modification DNA specificity domain Methyltransf_31 PF13847.6 ABX12506.1 - 1.7e-10 40.9 0.0 7.1e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ABX12506.1 - 2.3e-07 30.5 0.1 1.7e-06 27.7 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 ABX12506.1 - 5.1e-07 29.7 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX12506.1 - 6.9e-06 26.7 0.0 1.9e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 ABX12506.1 - 2.8e-05 23.9 0.0 0.00037 20.3 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 ABX12506.1 - 4.5e-05 23.0 0.2 4.5e-05 23.0 0.2 2.2 3 0 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 ABX12506.1 - 7.6e-05 22.6 0.4 0.00048 20.0 0.0 2.4 2 1 1 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 ABX12506.1 - 0.00042 19.9 0.0 0.0011 18.5 0.0 1.8 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 ABX12506.1 - 0.00044 20.8 0.1 0.0014 19.2 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ABX12506.1 - 0.00051 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 ABX12506.1 - 0.13 11.7 1.1 0.39 10.2 0.2 2.3 3 0 0 3 3 3 0 Putative methyltransferase E1_FCCH PF16190.5 ABX12507.1 - 0.088 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain CDT1_C PF16679.5 ABX12508.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Fib_alpha PF08702.10 ABX12508.1 - 2.9 8.1 5.7 3.7 7.7 2.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Phage_integrase PF00589.22 ABX12509.1 - 3.4e-16 59.5 0.5 6.6e-16 58.6 0.5 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_5 PF13102.6 ABX12509.1 - 6.7e-05 23.1 1.0 6.7e-05 23.1 1.0 2.2 2 0 0 2 2 2 1 Phage integrase SAM-like domain Phage_int_SAM_1 PF02899.17 ABX12509.1 - 0.0081 16.4 1.7 11 6.4 0.0 3.4 2 1 0 2 2 2 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 ABX12509.1 - 0.022 15.2 7.4 0.025 15.0 0.4 3.3 2 2 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain DUF5343 PF17278.2 ABX12510.1 - 6e-49 165.7 0.0 9e-49 165.1 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5343) HEPN_Swt1 PF18731.1 ABX12511.1 - 5.4e-13 49.3 0.2 9.4e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 Swt1-like HEPN Pre-PUA PF17832.1 ABX12511.1 - 0.0051 17.5 0.0 0.014 16.0 0.0 1.7 2 0 0 2 2 2 1 Pre-PUA-like domain HEPN_RiboL-PSP PF18735.1 ABX12511.1 - 0.0071 16.3 1.1 0.022 14.7 1.1 1.8 1 1 0 1 1 1 1 RiboL-PSP-HEPN Abi_2 PF07751.11 ABX12511.1 - 0.072 13.3 0.3 0.22 11.8 0.3 1.9 1 1 0 1 1 1 0 Abi-like protein H_kinase_N PF12282.8 ABX12511.1 - 0.14 12.1 0.1 1 9.3 0.1 2.0 2 0 0 2 2 2 0 Signal transduction histidine kinase LTD PF00932.19 ABX12512.1 - 4.7e-18 65.6 0.7 1.6e-17 63.9 0.7 1.9 1 0 0 1 1 1 1 Lamin Tail Domain MG2 PF01835.19 ABX12512.1 - 6e-15 55.5 5.7 0.0016 18.8 0.0 7.9 8 1 0 8 8 8 5 MG2 domain I-set PF07679.16 ABX12512.1 - 0.0064 16.5 0.0 21 5.2 0.0 4.0 3 0 0 3 3 3 1 Immunoglobulin I-set domain Arrestin_C PF02752.22 ABX12512.1 - 0.012 16.1 2.6 21 5.5 0.0 5.3 6 0 0 6 6 6 0 Arrestin (or S-antigen), C-terminal domain A2M_BRD PF07703.14 ABX12512.1 - 0.061 13.7 3.9 17 5.7 0.3 4.3 3 2 0 3 3 3 0 Alpha-2-macroglobulin bait region domain Ribo_biogen_C PF04034.13 ABX12513.1 - 2.2e-38 130.8 0.0 2.9e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 ABX12513.1 - 4.7e-07 29.5 0.1 8.1e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SBP_bac_5 PF00496.22 ABX12514.1 - 3e-26 92.3 10.2 4.1e-23 82.0 0.0 3.2 3 1 0 3 3 3 2 Bacterial extracellular solute-binding proteins, family 5 Middle CRF1 PF10380.9 ABX12514.1 - 0.0088 16.4 0.1 0.025 14.9 0.0 1.8 2 0 0 2 2 2 1 Transcription factor CRF1 Mrr_cat PF04471.12 ABX12515.1 - 0.00066 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Hjc PF01870.18 ABX12515.1 - 0.0064 16.5 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) NERD PF08378.11 ABX12515.1 - 0.047 14.2 0.1 0.076 13.5 0.1 1.4 1 0 0 1 1 1 0 Nuclease-related domain DUF2070 PF09843.9 ABX12516.1 - 2.8e-130 435.3 0.3 3.3e-130 435.0 0.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Caveolin PF01146.17 ABX12516.1 - 0.48 10.4 6.5 0.83 9.6 2.5 2.3 2 0 0 2 2 2 0 Caveolin Auto_anti-p27 PF06677.12 ABX12517.1 - 2.2e-11 43.7 2.3 3.5e-11 43.1 2.3 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CcdA PF07362.12 ABX12517.1 - 0.013 15.9 1.3 0.023 15.1 1.3 1.3 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA SUI1 PF01253.22 ABX12518.1 - 1.9e-18 66.7 0.0 2.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DTW PF03942.15 ABX12518.1 - 0.018 14.8 0.1 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 DTW domain Img2 PF05046.14 ABX12518.1 - 0.14 12.5 0.0 0.19 12.0 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) CPBP PF02517.16 ABX12519.1 - 2.2e-08 34.3 23.5 2.4e-07 31.0 23.5 2.5 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease TFIIB PF00382.19 ABX12520.1 - 4.4e-36 122.8 5.0 1.6e-18 66.5 1.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ABX12520.1 - 8.8e-12 44.4 2.3 1.5e-11 43.6 2.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Sigma70_r4 PF04545.16 ABX12520.1 - 0.00033 20.1 0.0 0.17 11.5 0.0 2.8 2 0 0 2 2 2 1 Sigma-70, region 4 Cyclin_C PF02984.19 ABX12520.1 - 0.0022 18.1 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 2 Cyclin, C-terminal domain HTH_AsnC-type PF13404.6 ABX12520.1 - 0.0061 16.4 0.0 0.27 11.1 0.0 2.7 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain Cyclin_N PF00134.23 ABX12520.1 - 0.0068 16.2 0.1 0.064 13.0 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain RPW8 PF05659.11 ABX12520.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 zf-ribbon_3 PF13248.6 ABX12520.1 - 0.053 12.9 5.1 0.4 10.1 5.1 2.2 1 1 0 1 1 1 0 zinc-ribbon domain RB_B PF01857.20 ABX12520.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain zf-HIT PF04438.16 ABX12520.1 - 0.076 12.9 5.5 0.23 11.4 1.0 2.5 2 0 0 2 2 2 0 HIT zinc finger Ribosomal_L37ae PF01780.19 ABX12520.1 - 0.11 12.6 1.3 1.5 8.9 0.3 2.6 2 0 0 2 2 2 0 Ribosomal L37ae protein family TPR_5 PF12688.7 ABX12520.1 - 0.14 12.4 1.5 0.36 11.1 0.2 2.2 2 1 0 2 2 2 0 Tetratrico peptide repeat zf-CCHC_5 PF14787.6 ABX12520.1 - 0.2 11.4 1.6 0.57 9.9 1.2 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger LacI PF00356.21 ABX12520.1 - 0.27 11.1 1.7 1.7 8.5 0.2 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Desulfoferrod_N PF06397.12 ABX12520.1 - 0.32 10.6 1.7 0.69 9.6 1.6 1.6 1 1 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zinc_ribbon_2 PF13240.6 ABX12520.1 - 0.34 10.7 7.4 4.5 7.1 0.8 2.4 2 0 0 2 2 2 0 zinc-ribbon domain MerR PF00376.23 ABX12520.1 - 0.4 10.5 1.4 2.6 7.9 0.0 2.7 3 0 0 3 3 3 0 MerR family regulatory protein HTH_36 PF13730.6 ABX12520.1 - 0.8 9.7 3.2 10 6.2 0.3 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain CofC PF01983.16 ABX12521.1 - 2.7e-22 79.0 4.5 3.5e-22 78.6 4.5 1.0 1 0 0 1 1 1 1 Guanylyl transferase CofC like NTP_transf_3 PF12804.7 ABX12521.1 - 0.00017 22.0 0.0 0.00019 21.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain UPF0052 PF01933.18 ABX12522.1 - 1.6e-57 195.0 0.0 1.9e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PCI PF01399.27 ABX12522.1 - 0.085 13.4 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 PCI domain FH2 PF02181.23 ABX12524.1 - 0.016 14.3 0.3 0.017 14.2 0.3 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain Med8 PF10232.9 ABX12524.1 - 0.023 14.3 0.4 0.026 14.1 0.4 1.0 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Methyltransf_11 PF08241.12 ABX12525.1 - 3.8e-19 69.1 0.0 1.2e-18 67.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABX12525.1 - 1.3e-18 67.3 0.0 1.7e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX12525.1 - 3.9e-18 65.9 0.0 1.3e-17 64.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABX12525.1 - 2.3e-17 63.2 0.0 3.5e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABX12525.1 - 8.4e-15 55.3 0.0 1.5e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 ABX12525.1 - 7e-10 38.3 0.1 1.6e-09 37.1 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1698) NodS PF05401.11 ABX12525.1 - 1.5e-09 37.8 0.0 1.9e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 ABX12525.1 - 6.6e-09 35.5 0.2 5.2e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Ubie_methyltran PF01209.18 ABX12525.1 - 1.3e-06 27.9 2.1 3.7e-06 26.5 0.1 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 ABX12525.1 - 1.5e-06 27.9 0.0 1.8e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW DOT1 PF08123.13 ABX12525.1 - 4.5e-06 26.3 0.0 0.00055 19.5 0.0 2.2 1 1 0 2 2 2 1 Histone methylation protein DOT1 CMAS PF02353.20 ABX12525.1 - 1.1e-05 24.9 0.3 1.6e-05 24.4 0.3 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 ABX12525.1 - 0.00028 20.8 0.1 0.00069 19.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ABX12525.1 - 0.00053 19.6 0.0 0.001 18.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 ABX12525.1 - 0.00088 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 ABX12525.1 - 0.0015 17.7 0.0 0.0026 16.9 0.0 1.3 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_2 PF00891.18 ABX12525.1 - 0.0019 17.5 0.0 0.0035 16.7 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain AdoMet_MTase PF07757.13 ABX12525.1 - 0.0022 18.3 0.6 0.0043 17.4 0.0 1.8 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase Methyltransf_5 PF01795.19 ABX12525.1 - 0.0027 17.3 0.0 0.061 12.8 0.0 2.1 2 0 0 2 2 2 1 MraW methylase family Methyltransf_32 PF13679.6 ABX12525.1 - 0.0048 16.9 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 ABX12525.1 - 0.0067 15.9 0.0 0.098 12.1 0.0 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain RVT_N PF13655.6 ABX12525.1 - 0.057 13.7 0.4 0.057 13.7 0.4 1.8 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase FlgD_ig PF13860.6 ABX12526.1 - 0.00045 20.0 0.0 0.56 10.1 0.0 2.7 2 0 0 2 2 2 2 FlgD Ig-like domain Cytochrom_B562 PF07361.11 ABX12526.1 - 0.031 14.9 2.6 3.5 8.3 0.1 4.1 3 0 0 3 3 3 0 Cytochrome b562 PH_4 PF15404.6 ABX12526.1 - 0.085 12.6 0.2 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain MG2 PF01835.19 ABX12526.1 - 0.1 13.0 0.0 11 6.5 0.0 3.0 3 0 0 3 3 3 0 MG2 domain DUF4363 PF14276.6 ABX12526.1 - 1.3 9.2 16.3 0.48 10.6 0.2 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4363) DAO PF01266.24 ABX12527.1 - 6.8e-15 55.5 2.1 6.8e-07 29.2 0.5 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ABX12527.1 - 7.2e-15 55.3 0.4 1e-14 54.8 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ABX12527.1 - 4.7e-13 48.8 0.4 2.1e-07 30.1 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 ABX12527.1 - 3.2e-12 46.4 0.3 1.1e-11 44.6 0.3 1.7 2 1 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 ABX12527.1 - 3.5e-12 46.1 0.8 9.3e-09 34.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 ABX12527.1 - 4.6e-10 38.8 0.7 4.4e-08 32.3 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 ABX12527.1 - 6.2e-09 35.5 3.9 8.4e-07 28.5 0.2 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABX12527.1 - 1e-07 31.4 0.1 1.5e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 ABX12527.1 - 2.9e-07 29.9 0.9 9.4e-07 28.2 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ABX12527.1 - 1.9e-06 28.0 0.1 3.8e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ABX12527.1 - 2.6e-06 26.8 2.7 1.1e-05 24.9 2.6 2.0 1 1 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 ABX12527.1 - 6.9e-06 26.5 1.5 0.011 16.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABX12527.1 - 9.2e-05 21.8 1.7 0.00022 20.6 1.6 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ABX12527.1 - 0.00082 18.7 0.1 0.0015 17.8 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 ABX12527.1 - 0.0012 19.1 0.1 0.0029 17.8 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain GDI PF00996.18 ABX12527.1 - 0.018 13.6 0.2 0.14 10.7 0.1 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor NAD_binding_7 PF13241.6 ABX12527.1 - 0.02 15.4 0.1 0.045 14.2 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 ABX12527.1 - 0.02 14.8 0.1 0.078 12.9 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 ABX12527.1 - 0.03 13.7 0.8 0.37 10.1 0.1 2.1 1 1 1 2 2 2 0 GMC oxidoreductase DUF3797 PF12677.7 ABX12528.1 - 0.023 14.6 0.1 0.035 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-ISL3 PF14690.6 ABX12528.1 - 0.048 14.3 0.9 0.12 13.1 0.9 1.9 1 1 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF99 PF01949.16 ABX12529.1 - 7.6e-55 185.2 0.0 8.5e-55 185.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF99 adh_short_C2 PF13561.6 ABX12530.1 - 3.2e-67 226.5 0.6 3.6e-67 226.3 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABX12530.1 - 8.6e-59 198.3 1.6 1e-58 198.0 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABX12530.1 - 4.1e-08 33.3 0.4 5.9e-08 32.8 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABX12530.1 - 9.4e-06 25.3 0.1 1.8e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ABX12530.1 - 0.00016 21.0 1.4 0.0002 20.6 1.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 ABX12530.1 - 0.0012 19.3 0.7 0.0024 18.4 0.2 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ABX12530.1 - 0.008 16.1 0.3 0.013 15.4 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 ABX12530.1 - 0.0082 15.5 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.15 ABX12530.1 - 0.012 15.5 0.3 0.022 14.6 0.3 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 ABX12530.1 - 0.18 11.1 2.1 0.45 9.8 2.1 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 ABX12530.1 - 0.19 11.8 1.7 0.32 11.1 0.3 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 ABX12531.1 - 3.1e-39 134.7 0.6 4.7e-39 134.1 0.6 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ABX12531.1 - 1e-19 71.0 0.0 1.5e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.12 ABX12531.1 - 2.8e-09 36.8 0.4 5.7e-09 35.8 0.4 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 ABX12531.1 - 3e-08 34.1 0.9 7e-08 33.0 0.6 1.8 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ABX12531.1 - 4.2e-08 32.7 0.1 6.5e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 ABX12531.1 - 2.7e-06 27.1 0.6 8.1e-06 25.6 0.6 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 ABX12531.1 - 5.2e-06 26.6 1.2 6.7e-06 26.2 0.3 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 ABX12531.1 - 0.00029 20.9 0.7 0.031 14.3 0.7 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 ABX12531.1 - 0.0022 17.9 2.5 0.0023 17.8 1.0 1.9 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_C PF03720.15 ABX12531.1 - 0.0041 17.5 0.1 0.011 16.2 0.1 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Rossmann-like PF10727.9 ABX12531.1 - 0.0049 16.7 0.1 0.014 15.2 0.1 1.8 2 0 0 2 2 2 1 Rossmann-like domain NAD_binding_10 PF13460.6 ABX12531.1 - 0.012 15.5 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_7 PF13241.6 ABX12531.1 - 0.017 15.5 0.2 0.041 14.3 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 ABX12531.1 - 0.023 14.9 0.7 0.14 12.4 0.7 2.3 1 1 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 ABX12531.1 - 0.037 14.8 0.1 0.083 13.7 0.1 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh_N PF03721.14 ABX12531.1 - 0.042 13.4 1.6 0.19 11.3 0.1 2.3 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-H2C2_5 PF13909.6 ABX12533.1 - 0.00011 21.9 0.8 0.00017 21.3 0.8 1.3 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 ABX12533.1 - 0.00082 19.7 1.3 0.0015 18.9 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ABX12533.1 - 0.0064 17.2 1.6 0.015 16.1 1.6 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger LIM_bind PF01803.16 ABX12533.1 - 0.025 14.1 0.1 0.038 13.5 0.1 1.2 1 0 0 1 1 1 0 LIM-domain binding protein Thioredoxin_4 PF13462.6 ABX12535.1 - 5.6e-32 111.2 0.0 7.2e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ABX12535.1 - 5e-16 59.1 0.7 8.5e-14 51.8 0.7 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ABX12535.1 - 8.6e-06 26.2 0.0 1.5e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 ABX12535.1 - 0.0078 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Ephrin_lbd PF01404.19 ABX12535.1 - 0.049 13.7 0.1 0.064 13.3 0.1 1.3 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain DUF555 PF04475.12 ABX12536.1 - 0.028 14.7 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF555) DUF998 PF06197.13 ABX12537.1 - 7.2 6.2 21.9 5 6.7 12.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF998) IMS PF00817.20 ABX12538.1 - 5.1e-42 143.4 0.3 5e-41 140.2 0.1 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 ABX12538.1 - 1.6e-10 41.7 0.7 3.4e-10 40.7 0.7 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 ABX12538.1 - 2.7e-07 30.5 0.0 6.3e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DUF2524 PF10732.9 ABX12538.1 - 0.011 16.0 0.8 0.011 16.0 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Cdd1 PF11731.8 ABX12538.1 - 0.018 15.3 0.0 0.062 13.6 0.0 1.9 1 0 0 1 1 1 0 Pathogenicity locus DUF5071 PF16804.5 ABX12538.1 - 0.04 14.2 0.4 0.11 12.8 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) HHH_5 PF14520.6 ABX12538.1 - 0.041 14.5 0.1 0.26 11.9 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain GLTP PF08718.11 ABX12538.1 - 0.089 13.1 2.0 1.3 9.2 0.6 2.2 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) HHH_8 PF14716.6 ABX12538.1 - 0.14 12.5 0.1 1.7 9.1 0.0 2.5 2 1 0 2 2 2 0 Helix-hairpin-helix domain DUF1805 PF08827.11 ABX12538.1 - 0.15 12.4 0.2 11 6.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) PB1 PF00564.24 ABX12539.1 - 0.04 13.8 1.0 0.056 13.4 1.0 1.2 1 0 0 1 1 1 0 PB1 domain Alba PF01918.21 ABX12540.1 - 1.4e-09 37.6 0.3 1.9e-09 37.2 0.3 1.3 1 0 0 1 1 1 1 Alba LysE PF01810.18 ABX12542.1 - 2.3e-28 99.0 14.6 2.9e-28 98.7 14.6 1.0 1 0 0 1 1 1 1 LysE type translocator PAC2 PF09754.9 ABX12543.1 - 1.6e-24 87.1 0.0 1.9e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 PAC2 family DS PF01916.17 ABX12544.1 - 4.8e-90 301.7 0.1 5.4e-90 301.5 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Inos-1-P_synth PF01658.17 ABX12545.1 - 2.2e-28 98.7 0.3 5.6e-28 97.4 0.1 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase CN_hydrolase PF00795.22 ABX12546.1 - 5e-21 75.2 0.0 6.5e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SMC_N PF02463.19 ABX12547.1 - 5.5e-51 173.1 54.1 2.3e-33 115.5 0.3 4.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABX12547.1 - 1.7e-20 74.4 7.7 1.7e-20 74.4 7.7 6.3 2 2 3 6 6 3 1 AAA domain SMC_hinge PF06470.13 ABX12547.1 - 4.7e-17 62.4 0.0 1.9e-16 60.4 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ABX12547.1 - 5e-08 33.1 24.0 0.0002 21.3 7.9 4.3 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABX12547.1 - 3.4e-06 26.7 0.0 8.8e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 ABX12547.1 - 1.8e-05 24.7 92.9 0.0028 17.4 42.2 4.3 2 2 1 3 3 3 2 AAA ATPase domain DUF2968 PF11180.8 ABX12547.1 - 0.00076 19.2 12.7 0.00076 19.2 12.7 5.8 4 2 1 6 6 6 1 Protein of unknown function (DUF2968) APG6_N PF17675.1 ABX12547.1 - 0.012 16.1 7.3 0.012 16.1 7.3 9.4 3 2 6 9 9 8 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 ABX12547.1 - 0.012 15.8 4.8 0.012 15.8 4.8 9.7 4 2 9 13 13 13 0 TATA element modulatory factor 1 TATA binding ABC_tran PF00005.27 ABX12547.1 - 0.018 15.6 1.3 0.018 15.6 1.3 6.6 3 3 0 3 3 1 0 ABC transporter Tubulin_3 PF14881.6 ABX12547.1 - 0.037 13.7 3.3 0.096 12.4 1.0 2.8 1 1 1 2 2 2 0 Tubulin domain DUF4107 PF13389.6 ABX12547.1 - 0.14 12.3 4.1 0.84 9.8 4.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) AAA_27 PF13514.6 ABX12547.1 - 0.16 11.5 0.0 0.16 11.5 0.0 5.4 6 1 0 6 6 6 0 AAA domain MAD PF05557.13 ABX12547.1 - 0.44 8.9 106.8 0.0063 14.9 27.5 4.1 2 2 2 4 4 4 0 Mitotic checkpoint protein DUF4522 PF15022.6 ABX12547.1 - 0.45 10.8 3.8 4.2 7.6 3.8 2.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) ATG16 PF08614.11 ABX12547.1 - 0.59 10.3 90.2 0.034 14.4 24.0 5.7 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) AAA_16 PF13191.6 ABX12547.1 - 0.94 9.8 0.0 0.94 9.8 0.0 3.1 3 2 0 3 3 2 0 AAA ATPase domain ABC_tran PF00005.27 ABX12548.1 - 9.4e-34 116.9 0.0 1.3e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 ABX12548.1 - 3.4e-17 62.7 0.0 1.8e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_16 PF13191.6 ABX12548.1 - 5e-05 23.7 0.0 8.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ABX12548.1 - 7.2e-05 23.1 0.1 0.059 13.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ABX12548.1 - 0.00011 22.1 0.9 0.24 11.1 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABX12548.1 - 0.00067 19.1 0.5 0.011 15.2 0.5 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ABX12548.1 - 0.00094 19.1 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ABX12548.1 - 0.0011 18.6 0.1 0.0026 17.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 ABX12548.1 - 0.0016 18.9 0.2 0.023 15.1 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ABX12548.1 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 ABX12548.1 - 0.0026 17.1 0.0 0.0046 16.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_15 PF13175.6 ABX12548.1 - 0.018 14.8 0.1 0.028 14.1 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 ABX12548.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 ABX12548.1 - 0.021 15.3 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ABX12548.1 - 0.025 13.6 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4974 PF16344.5 ABX12548.1 - 0.031 14.3 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) AAA_25 PF13481.6 ABX12548.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 1 0 AAA domain DUF87 PF01935.17 ABX12548.1 - 0.058 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TsaE PF02367.17 ABX12548.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 ABX12548.1 - 0.067 13.6 0.1 0.23 11.9 0.1 2.0 2 1 0 2 2 1 0 RNA helicase AAA_33 PF13671.6 ABX12548.1 - 0.083 13.1 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 ABX12548.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 ABX12548.1 - 0.098 13.2 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ABX12548.1 - 0.11 12.5 0.1 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 ABX12548.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 ABX12548.1 - 0.14 11.5 0.8 4 6.8 0.1 2.4 2 1 0 2 2 2 0 Bacterial TniB protein Membralin PF09746.9 ABX12548.1 - 0.14 11.1 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein NACHT PF05729.12 ABX12548.1 - 0.16 11.9 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 ABX12548.1 - 0.2 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Methyltransf_33 PF10017.9 ABX12549.1 - 2.4e-103 345.5 1.1 2.8e-103 345.3 1.1 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_28 PF02636.17 ABX12549.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 ABX12549.1 - 0.15 12.8 0.0 0.34 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FMN_red PF03358.15 ABX12550.1 - 8.7e-31 106.8 0.0 1e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ABX12550.1 - 8.3e-08 32.2 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold SPC25 PF06703.11 ABX12550.1 - 0.087 12.6 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Thioredoxin_4 PF13462.6 ABX12551.1 - 7.2e-32 110.8 0.1 9.6e-32 110.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ABX12551.1 - 1.9e-10 40.9 1.5 4.4e-07 29.9 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ABX12551.1 - 3.4e-07 30.7 0.3 7.8e-07 29.5 0.3 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 ABX12551.1 - 3.5e-07 30.1 0.2 1.9e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin PF00085.20 ABX12551.1 - 0.093 12.7 0.2 0.85 9.6 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin HATPase_c PF02518.26 ABX12552.1 - 3.7e-19 69.3 0.1 6.3e-19 68.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABX12552.1 - 3.9e-13 49.2 0.1 1.1e-12 47.8 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 ABX12552.1 - 5.6e-09 35.8 0.5 1.7e-08 34.3 0.1 2.0 2 0 0 2 2 2 1 GHKL domain HATPase_c_2 PF13581.6 ABX12552.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ABX12552.1 - 0.0002 21.2 0.0 0.00046 20.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Prefoldin_3 PF13758.6 ABX12552.1 - 0.095 12.8 1.6 0.14 12.2 0.4 1.9 2 0 0 2 2 2 0 Prefoldin subunit FGE-sulfatase PF03781.16 ABX12553.1 - 4.1e-49 167.5 2.9 7.3e-49 166.7 2.9 1.4 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 ABX12553.1 - 5.6e-09 36.6 0.1 3.8e-08 33.9 0.0 2.4 3 1 0 3 3 3 1 DinB superfamily ProRS-C_1 PF09180.11 ABX12554.1 - 4.2e-22 78.1 0.8 1.2e-21 76.7 0.8 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 ABX12554.1 - 2.3e-20 72.5 1.1 2.3e-20 72.5 1.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ABX12554.1 - 1.9e-18 67.0 0.0 3.1e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PEP-utilizers PF00391.23 ABX12556.1 - 2.6e-12 46.3 0.0 4.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PPDK_N PF01326.19 ABX12556.1 - 1e-11 44.7 1.9 2.4e-06 27.1 0.2 3.3 2 1 0 3 3 3 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain SPACA9 PF15120.6 ABX12556.1 - 0.016 15.0 1.1 0.98 9.2 0.4 2.9 1 1 1 2 2 2 0 Sperm acrosome-associated protein 9 Peptidase_C26 PF07722.13 ABX12557.1 - 2.8e-27 95.9 0.0 5.5e-26 91.7 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 ABX12557.1 - 3.8e-19 69.2 0.0 4.5e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_5 PF13507.6 ABX12557.1 - 0.00081 18.6 0.8 1 8.4 0.0 2.6 1 1 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 ABX12557.1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.3 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain NTP_transferase PF00483.23 ABX12558.1 - 8.3e-11 41.9 0.6 3.7e-10 39.8 0.1 2.1 2 1 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ABX12558.1 - 1.8e-10 41.4 0.0 2.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 ABX12558.1 - 0.0026 17.6 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Sulfatase PF00884.23 ABX12559.1 - 1.2e-25 90.6 0.0 1.1e-23 84.1 0.0 2.1 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 ABX12559.1 - 5.1e-10 39.5 0.0 4.3e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 ABX12559.1 - 4.6e-06 26.5 0.3 0.087 12.4 0.4 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2183 PF09949.9 ABX12559.1 - 0.028 14.8 0.1 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) DASH_Dam1 PF08653.10 ABX12559.1 - 0.048 13.5 0.2 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF229 PF02995.17 ABX12559.1 - 0.052 12.1 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyphos_transf PF04464.14 ABX12560.1 - 1.7e-17 63.5 6.6 3.2e-17 62.6 6.6 1.4 1 1 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Sulfatase PF00884.23 ABX12561.1 - 5.6e-06 26.0 0.3 8.5e-06 25.4 0.3 1.3 1 0 0 1 1 1 1 Sulfatase DUF4131 PF13567.6 ABX12561.1 - 0.33 10.6 2.0 2.1 8.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) HAD PF12710.7 ABX12562.1 - 5.3e-14 53.0 0.0 7.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABX12562.1 - 9.5e-12 45.6 0.1 1.4e-10 41.8 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ABX12562.1 - 1.8e-05 24.6 0.1 0.0023 17.7 0.1 2.8 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase F420_ligase PF01996.16 ABX12563.1 - 4.3e-55 186.7 2.1 5.4e-55 186.4 2.1 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase PHP_C PF13263.6 ABX12564.1 - 5.6e-11 42.0 0.0 1.8e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 PHP-associated Glyco_tranf_2_4 PF13704.6 ABX12564.1 - 0.03 14.8 0.4 0.55 10.8 0.1 2.5 2 1 0 2 2 2 0 Glycosyl transferase family 2 PHP PF02811.19 ABX12564.1 - 0.071 13.4 0.3 0.092 13.0 0.3 1.4 1 1 0 1 1 1 0 PHP domain CNPase PF05881.12 ABX12564.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) TusA PF01206.17 ABX12565.1 - 4.7e-22 77.6 0.0 5.2e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA PALP PF00291.25 ABX12566.1 - 5e-62 210.0 0.0 7.1e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GCV_H PF01597.19 ABX12567.1 - 0.05 13.5 0.5 0.11 12.3 0.1 1.8 1 1 0 1 1 1 0 Glycine cleavage H-protein Chalcone PF02431.15 ABX12567.1 - 0.13 11.7 2.4 0.15 11.4 2.3 1.3 1 1 0 1 1 1 0 Chalcone-flavanone isomerase DHR10 PF18595.1 ABX12567.1 - 2.2 8.4 9.1 1.5 8.9 2.0 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Pyr_redox_2 PF07992.14 ABX12568.1 - 5.7e-54 183.3 0.8 6.6e-54 183.1 0.8 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABX12568.1 - 5.7e-25 88.2 2.6 4.6e-21 75.4 0.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABX12568.1 - 2.1e-18 66.7 2.4 8.3e-17 61.5 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABX12568.1 - 1.2e-06 27.9 0.3 0.0061 15.7 0.1 3.8 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ABX12568.1 - 4e-05 22.9 3.0 0.00057 19.1 0.2 2.7 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.24 ABX12568.1 - 4.6e-05 23.2 3.1 0.037 13.6 0.0 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ABX12568.1 - 0.00012 21.6 0.1 0.00038 19.9 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ABX12568.1 - 0.0002 20.7 0.0 0.0018 17.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 ABX12568.1 - 0.00022 20.6 2.2 0.0087 15.3 0.1 2.6 2 1 1 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 ABX12568.1 - 0.00027 20.2 0.2 0.33 10.0 0.0 3.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ABX12568.1 - 0.0031 17.7 0.2 0.015 15.5 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABX12568.1 - 0.0041 15.9 2.3 0.034 12.9 0.1 2.8 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_7 PF13241.6 ABX12568.1 - 0.024 15.1 1.9 0.07 13.6 0.4 2.3 2 2 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 ABX12568.1 - 0.034 14.1 3.8 15 5.5 0.0 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding XdhC_C PF13478.6 ABX12568.1 - 0.083 13.4 0.2 0.18 12.3 0.1 1.6 2 0 0 2 2 2 0 XdhC Rossmann domain CBS PF00571.28 ABX12569.1 - 2.3e-28 98.4 5.3 6.6e-15 55.3 0.4 2.2 2 0 0 2 2 2 2 CBS domain PTH2 PF01981.16 ABX12569.1 - 0.0059 16.9 1.1 0.013 15.8 0.3 1.8 1 1 1 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 Phage_sheath_1 PF04984.14 ABX12569.1 - 0.025 14.5 0.1 0.037 13.9 0.1 1.4 1 1 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain TmoB PF06234.12 ABX12569.1 - 0.14 12.3 2.3 0.95 9.6 0.8 2.8 2 1 1 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) ATPase_2 PF01637.18 ABX12569.1 - 0.2 11.6 6.0 0.23 11.3 6.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Usp PF00582.26 ABX12570.1 - 4.2e-27 95.4 0.0 5.3e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Ribosomal_S30AE PF02482.19 ABX12571.1 - 4.4e-05 24.2 0.5 5.4e-05 23.9 0.5 1.1 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Mt_ATP_synt PF15704.5 ABX12571.1 - 0.027 14.4 0.2 0.032 14.2 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit Ldh_1_N PF00056.23 ABX12572.1 - 7.8e-23 81.1 0.2 1.2e-22 80.5 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ABX12572.1 - 2.3e-17 63.4 0.1 7.3e-17 61.8 0.1 1.8 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 ABX12572.1 - 9.2e-08 31.8 0.2 8.3e-06 25.5 0.0 2.3 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase 3HCDH_N PF02737.18 ABX12572.1 - 0.0078 16.1 2.2 0.017 15.0 0.5 2.4 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ABX12572.1 - 0.014 16.0 0.2 0.036 14.7 0.2 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ABX12572.1 - 0.031 14.3 0.1 0.057 13.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 ABX12572.1 - 0.093 12.3 2.2 1.1 8.8 2.2 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 ABX12574.1 - 9.4e-65 218.1 0.0 1.1e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ABX12574.1 - 1.9e-14 53.6 0.5 7.2e-07 28.6 0.1 3.0 1 1 1 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 ABX12574.1 - 3.3e-09 36.6 0.3 7.5e-09 35.4 0.0 1.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABX12574.1 - 2.2e-08 34.2 0.0 4.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ABX12574.1 - 3.2e-08 33.2 0.0 4.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABX12574.1 - 1.8e-07 30.7 0.0 2.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ABX12574.1 - 8.8e-07 28.0 0.0 1.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 ABX12574.1 - 2.4e-06 27.4 0.3 0.00012 21.8 0.1 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ABX12574.1 - 1.6e-05 24.3 0.1 2.5e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABX12574.1 - 7.7e-05 21.9 0.0 0.00064 18.9 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 ABX12574.1 - 0.00042 19.5 0.1 0.00069 18.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ABX12574.1 - 0.0038 17.7 0.0 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ABX12574.1 - 0.0077 15.5 0.0 0.021 14.1 0.0 1.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 ABX12574.1 - 0.011 14.6 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 ABX12574.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ABX12574.1 - 0.029 14.3 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding GDI PF00996.18 ABX12574.1 - 0.032 12.8 0.0 0.052 12.1 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor TrkA_N PF02254.18 ABX12574.1 - 0.032 14.5 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NIR_SIR PF01077.22 ABX12575.1 - 5.2e-42 143.0 0.0 8.7e-32 109.8 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 ABX12575.1 - 8.4e-31 105.6 0.1 4.1e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain DUF2283 PF10049.9 ABX12575.1 - 0.14 12.4 0.2 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2283) Rhodanese PF00581.20 ABX12576.1 - 4.8e-33 113.9 0.0 4.6e-16 59.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain TPR_1 PF00515.28 ABX12577.1 - 2.4e-24 84.1 3.9 6.9e-08 32.0 0.0 6.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 ABX12577.1 - 3.9e-24 82.8 5.4 6.4e-07 29.0 0.0 6.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 ABX12577.1 - 7.9e-19 67.1 6.3 8.9e-09 34.9 0.0 5.3 4 1 2 6 6 5 3 TPR repeat TPR_8 PF13181.6 ABX12577.1 - 8.7e-18 63.0 9.4 0.00076 19.5 0.0 6.4 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 ABX12577.1 - 4.9e-15 54.7 0.1 0.00022 21.4 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 ABX12577.1 - 2.1e-14 53.0 2.7 0.00057 20.5 0.0 5.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 ABX12577.1 - 5.1e-14 52.5 2.0 1.5e-07 31.8 0.0 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ABX12577.1 - 4.2e-13 49.7 0.0 1.7e-06 28.5 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 ABX12577.1 - 1.3e-11 44.6 3.0 1.8e-05 24.9 0.1 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 ABX12577.1 - 3.9e-09 36.6 3.5 0.25 12.1 0.0 5.9 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 ABX12577.1 - 3.2e-08 33.6 0.0 9.9e-05 22.4 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ABX12577.1 - 7.1e-08 32.6 0.2 4.2e-07 30.1 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ABX12577.1 - 1.1e-07 31.4 0.6 0.6 10.3 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ABX12577.1 - 1e-05 25.5 0.3 0.31 11.2 0.0 4.0 2 1 2 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 ABX12577.1 - 0.001 18.9 1.5 11 6.1 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat HTH_27 PF13463.6 ABX12577.1 - 0.002 18.6 0.1 0.0058 17.1 0.1 1.8 1 0 0 1 1 1 1 Winged helix DNA-binding domain MIT PF04212.18 ABX12577.1 - 0.0023 18.0 5.7 0.27 11.3 0.9 4.3 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TrmB PF01978.19 ABX12577.1 - 0.0063 16.4 0.2 1.4 8.8 0.0 2.9 2 1 1 3 3 2 1 Sugar-specific transcriptional regulator TrmB DUF424 PF04242.13 ABX12577.1 - 0.0066 16.7 0.5 0.31 11.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF424) DUF627 PF04781.12 ABX12577.1 - 0.012 15.6 2.1 1.4 9.0 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF627) TPR_20 PF14561.6 ABX12577.1 - 0.013 15.8 3.6 13 6.2 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 ABX12577.1 - 0.025 14.7 0.2 3.1 7.9 0.0 3.3 2 1 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region Coatomer_E PF04733.14 ABX12577.1 - 0.025 14.0 2.0 3.1 7.1 0.0 2.7 2 1 1 3 3 3 0 Coatomer epsilon subunit DUF4919 PF16266.5 ABX12577.1 - 0.045 13.7 1.1 0.53 10.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) NARP1 PF12569.8 ABX12577.1 - 0.056 12.3 4.7 0.33 9.8 0.0 2.7 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 TOM20_plant PF06552.12 ABX12577.1 - 0.11 12.2 2.9 0.13 12.0 0.1 2.5 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_3 PF07720.12 ABX12577.1 - 0.18 11.9 1.3 35 4.5 0.0 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat Collagen PF01391.18 ABX12578.1 - 6.1e-61 202.1 232.2 7.4e-09 35.2 34.2 7.7 1 1 3 4 4 4 3 Collagen triple helix repeat (20 copies) MMR_HSR1_Xtn PF16897.5 ABX12580.1 - 2.6e-29 101.3 4.2 4.9e-29 100.5 4.2 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ABX12580.1 - 3.5e-23 81.8 0.4 1.1e-22 80.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 ABX12580.1 - 2.7e-21 75.3 0.0 5.5e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 ABX12580.1 - 2.9e-16 59.4 2.2 1.8e-13 50.3 0.0 2.3 1 1 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ABX12580.1 - 1.7e-06 28.1 1.8 0.0048 16.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ABX12580.1 - 0.0001 22.4 0.3 0.079 13.0 0.2 2.7 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 ABX12580.1 - 0.00034 20.0 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Arf PF00025.21 ABX12580.1 - 0.0019 17.6 1.5 0.052 13.0 0.1 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family MnmE_helical PF12631.7 ABX12580.1 - 0.0026 18.0 0.1 0.0033 17.6 0.1 1.1 1 0 0 1 1 1 1 MnmE helical domain SRPRB PF09439.10 ABX12580.1 - 0.011 15.2 1.8 0.015 14.7 0.1 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MeaB PF03308.16 ABX12580.1 - 0.03 13.3 0.3 0.19 10.7 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 ABX12580.1 - 0.032 14.5 0.3 0.072 13.3 0.3 1.6 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 ABX12580.1 - 0.053 13.1 1.8 6.9 6.3 0.1 2.4 2 0 0 2 2 2 0 Ras family AAA_33 PF13671.6 ABX12580.1 - 0.055 13.6 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ABX12580.1 - 0.13 12.6 0.7 0.7 10.3 0.1 2.3 1 1 1 2 2 2 0 AAA ATPase domain DUF1002 PF06207.11 ABX12580.1 - 6.4 6.2 8.5 0.89 9.0 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1002) Med2 PF11214.8 ABX12580.1 - 6.8 6.9 8.2 0.38 10.9 2.8 1.7 2 0 0 2 2 2 0 Mediator complex subunit 2 Hydrolase_3 PF08282.12 ABX12581.1 - 6.8e-32 111.2 2.4 4.2e-23 82.4 0.7 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ABX12581.1 - 1.6e-07 31.1 0.1 0.00022 20.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 ABX12581.1 - 0.00011 22.6 0.4 0.041 14.2 0.4 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 ABX12581.1 - 0.00034 19.8 0.1 0.0027 16.9 0.1 2.0 1 1 0 1 1 1 1 Trehalose-phosphatase HAD PF12710.7 ABX12581.1 - 0.0061 17.0 0.1 0.17 12.3 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF5018 PF16410.5 ABX12581.1 - 0.034 12.9 0.2 0.067 11.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5018) HAD_2 PF13419.6 ABX12581.1 - 0.034 14.2 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ABX12581.1 - 0.064 13.4 0.1 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DALR_1 PF05746.15 ABX12582.1 - 3.6e-28 98.1 0.4 5.1e-27 94.4 0.0 2.7 3 0 0 3 3 3 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 ABX12582.1 - 5.8e-27 94.6 2.6 2.9e-23 82.4 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 ABX12582.1 - 3e-15 56.6 0.0 1e-14 54.9 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 ABX12582.1 - 0.00043 19.7 0.0 0.00088 18.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ABX12582.1 - 0.027 13.2 0.1 0.051 12.3 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (M) PNPase PF03726.14 ABX12582.1 - 0.057 13.9 4.8 6.1 7.4 0.5 3.0 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain NUMOD1 PF07453.13 ABX12582.1 - 0.26 11.6 2.4 0.73 10.2 0.1 3.2 3 0 0 3 3 3 0 NUMOD1 domain PAD_porph PF04371.15 ABX12583.1 - 1.9e-30 106.3 0.0 5.6e-30 104.7 0.0 1.6 2 0 0 2 2 2 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 ABX12583.1 - 0.15 11.1 0.1 0.29 10.2 0.1 1.5 1 1 0 1 1 1 0 Amidinotransferase RepC PF06504.11 ABX12584.1 - 0.041 13.1 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Replication protein C (RepC) zinc_ribbon_15 PF17032.5 ABX12585.1 - 0.0047 17.7 0.2 0.0057 17.4 0.2 1.1 1 0 0 1 1 1 1 zinc-ribbon family TF_Zn_Ribbon PF08271.12 ABX12585.1 - 0.024 14.2 3.1 0.13 11.7 3.2 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 ABX12585.1 - 0.046 13.8 0.2 0.067 13.2 0.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-LITAF-like PF10601.9 ABX12585.1 - 0.065 13.5 0.4 2 8.7 0.0 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-B_box PF00643.24 ABX12585.1 - 0.13 12.4 2.6 2.2 8.5 0.5 2.1 2 0 0 2 2 2 0 B-box zinc finger GCD14 PF08704.10 ABX12586.1 - 1.8e-37 129.4 0.1 2.3e-37 129.0 0.1 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 ABX12586.1 - 6.6e-12 45.6 0.1 1e-11 45.0 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ABX12586.1 - 1.2e-08 34.9 0.0 2.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 ABX12586.1 - 3.3e-07 31.3 0.0 7.9e-07 30.1 0.0 1.6 1 1 1 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX12586.1 - 7.2e-07 29.8 0.0 1.4e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABX12586.1 - 1.2e-06 28.0 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 ABX12586.1 - 1e-05 25.1 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 ABX12586.1 - 3.9e-05 22.9 0.0 5.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.17 ABX12586.1 - 5.4e-05 22.5 0.1 8.5e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_11 PF08241.12 ABX12586.1 - 9.3e-05 23.0 0.0 0.00019 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 ABX12586.1 - 0.0001 21.5 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltr_RsmB-F PF01189.17 ABX12586.1 - 0.00012 21.8 0.0 0.00027 20.6 0.0 1.5 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_16 PF10294.9 ABX12586.1 - 0.00018 21.3 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 ABX12586.1 - 0.00047 19.7 0.0 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ABX12586.1 - 0.00062 20.5 0.0 0.0014 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ABX12586.1 - 0.0016 18.4 0.1 0.0036 17.2 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ABX12586.1 - 0.0058 16.0 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14_N PF14801.6 ABX12586.1 - 0.0066 16.3 1.4 0.012 15.5 0.1 2.0 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term Met_10 PF02475.16 ABX12586.1 - 0.024 14.4 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 ABX12586.1 - 0.03 14.2 0.0 0.049 13.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 ABX12586.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF43 PF01861.16 ABX12586.1 - 0.09 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Carb_kinase PF01256.17 ABX12587.1 - 6e-46 156.9 0.3 7.1e-46 156.7 0.3 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 ABX12587.1 - 4.2e-08 32.9 0.0 7.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 ABX12587.1 - 1.6e-06 27.7 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Peptidase_M20 PF01546.28 ABX12588.1 - 2.5e-31 109.0 0.0 3.3e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ABX12588.1 - 8.6e-13 48.2 0.0 2.2e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Tox-PL-2 PF15643.6 ABX12588.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Papain fold toxin 2 DoxX PF07681.12 ABX12589.1 - 7.8e-13 48.8 4.0 7.8e-13 48.8 4.0 1.5 1 1 0 1 1 1 1 DoxX DoxX_2 PF13564.6 ABX12589.1 - 1.8e-05 24.7 3.6 2.6e-05 24.3 3.6 1.3 1 1 0 1 1 1 1 DoxX-like family DoxD PF04173.13 ABX12589.1 - 0.0004 20.3 1.9 0.0004 20.3 1.9 1.6 1 1 1 2 2 2 1 TQO small subunit DoxD Proteasome PF00227.26 ABX12590.1 - 9.4e-46 155.7 0.0 1.1e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PUA PF01472.20 ABX12591.1 - 3.1e-17 62.3 0.1 4.7e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 ABX12591.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 UPF0113 PUA domain Homoserine_dh PF00742.19 ABX12592.1 - 9.1e-56 188.5 0.2 1.5e-55 187.8 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 ABX12592.1 - 6.1e-09 36.6 0.0 1.4e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 ABX12592.1 - 5.7e-07 29.5 0.1 1.2e-06 28.5 0.1 1.5 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GFO_IDH_MocA PF01408.22 ABX12592.1 - 0.15 12.9 0.0 0.29 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold SelR PF01641.18 ABX12593.1 - 7.8e-54 180.9 0.5 8.9e-54 180.7 0.5 1.0 1 0 0 1 1 1 1 SelR domain ADD_ATRX PF17981.1 ABX12593.1 - 0.0026 17.6 0.8 0.75 9.7 0.1 2.3 2 0 0 2 2 2 2 Cysteine Rich ADD domain HECT_2 PF09814.9 ABX12593.1 - 0.0045 15.9 1.7 0.29 9.9 0.1 2.0 1 1 1 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 ABX12593.1 - 0.005 17.0 1.8 0.016 15.4 1.8 1.8 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2HE PF16278.5 ABX12593.1 - 0.029 14.8 0.7 6.6 7.3 0.3 2.3 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF983 PF06170.12 ABX12593.1 - 0.2 12.1 1.9 9.6 6.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zinc_ribbon_2 PF13240.6 ABX12593.1 - 0.5 10.1 10.2 1.3 8.9 1.4 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Thy1 PF02511.15 ABX12594.1 - 9.3e-35 120.1 1.5 1.7e-17 63.9 1.4 2.2 2 0 0 2 2 2 2 Thymidylate synthase complementing protein DUF4722 PF15849.5 ABX12594.1 - 0.04 13.6 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4722) EMC3_TMCO1 PF01956.16 ABX12594.1 - 1.2 8.8 3.9 0.79 9.4 0.6 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Paramyxo_P PF01806.17 ABX12595.1 - 0.028 13.9 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region CdvA PF18822.1 ABX12596.1 - 1.3e-33 115.4 9.3 2.3e-33 114.7 9.3 1.3 1 0 0 1 1 1 1 CdvA-like coiled-coil domain ABC_tran_CTD PF16326.5 ABX12596.1 - 0.19 12.0 6.6 0.46 10.8 3.5 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF948 PF06103.11 ABX12596.1 - 5 7.5 6.1 6.1 7.2 1.8 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) AMP-binding PF00501.28 ABX12597.1 - 4.4e-91 305.6 0.0 5.4e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABX12597.1 - 6.3e-27 94.4 2.7 7e-26 91.0 0.4 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ABX12597.1 - 1e-14 54.2 5.1 2.4e-14 53.0 5.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF3201 PF11447.8 ABX12597.1 - 0.053 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) PAS_9 PF13426.7 ABX12598.1 - 3.5e-10 40.1 0.0 6.3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ABX12598.1 - 1.2e-09 38.2 0.0 1.9e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 PAS fold PAS_3 PF08447.12 ABX12598.1 - 3.8e-06 27.1 0.0 5.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 ABX12598.1 - 2.3e-05 24.6 0.0 3.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 PAS fold DUF1366 PF07104.11 ABX12598.1 - 0.033 13.9 0.3 0.41 10.4 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1366) Retrotrans_gag PF03732.17 ABX12598.1 - 0.18 12.1 2.6 0.27 11.5 0.3 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein XPG_I PF00867.18 ABX12599.1 - 3.7e-23 81.7 0.0 1e-22 80.2 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 ABX12599.1 - 8.9e-22 77.5 0.0 5.1e-21 75.0 0.0 2.0 1 1 1 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 ABX12599.1 - 0.0002 21.9 0.0 0.0007 20.1 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF4878 PF12870.7 ABX12599.1 - 0.013 15.8 1.7 0.023 15.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) BRF1 PF07741.13 ABX12599.1 - 0.018 15.3 0.5 0.018 15.3 0.5 1.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain TrmB PF01978.19 ABX12601.1 - 6.8e-14 51.5 0.0 1.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_9 PF08221.11 ABX12601.1 - 0.00011 22.2 0.0 0.00076 19.5 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_IclR PF09339.10 ABX12601.1 - 0.0025 17.6 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain Rrf2 PF02082.20 ABX12601.1 - 0.048 14.0 0.0 0.22 11.9 0.0 2.1 1 0 0 1 1 1 0 Transcriptional regulator Med12 PF09497.10 ABX12601.1 - 0.073 13.4 0.2 5.6 7.3 0.0 2.7 3 0 0 3 3 3 0 Transcription mediator complex subunit Med12 HTH_5 PF01022.20 ABX12601.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Peptidase_M10 PF00413.24 ABX12602.1 - 3e-09 36.9 0.1 6.7e-09 35.8 0.1 1.9 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 ABX12602.1 - 0.0019 17.9 0.1 0.0034 17.0 0.1 1.4 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.9 ABX12602.1 - 0.03 13.3 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.13 ABX12602.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF4953 PF16313.5 ABX12602.1 - 0.14 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 ABX12602.1 - 0.35 11.0 0.1 0.35 11.0 0.1 1.8 2 1 0 2 2 2 0 Metallo-peptidase family M12 Response_reg PF00072.24 ABX12603.1 - 1.4e-14 54.2 0.1 2.8e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain NitrOD5 PF11537.8 ABX12603.1 - 0.0002 21.4 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 Nitrosopumilus output domain 5 B2-adapt-app_C PF09066.10 ABX12603.1 - 0.048 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain SAPIS-gp6 PF16722.5 ABX12604.1 - 0.0073 16.7 0.1 0.01 16.3 0.1 1.2 1 0 0 1 1 1 1 Pathogenicity island protein gp6 in Staphylococcus Nitroreductase PF00881.24 ABX12605.1 - 1.6e-25 90.2 0.1 6.1e-14 52.4 0.0 2.1 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 ABX12605.1 - 1.9e-10 40.7 0.0 0.00022 20.9 0.0 3.0 1 1 1 3 3 3 3 Putative TM nitroreductase AsnC_trans_reg PF01037.21 ABX12606.1 - 8.6e-10 38.5 0.1 1e-09 38.2 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain KOG2701 PF09762.9 ABX12606.1 - 0.039 14.2 0.3 0.044 14.0 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) PDE4_UCR PF18100.1 ABX12606.1 - 0.047 14.3 0.2 0.064 13.9 0.2 1.4 1 1 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) DUF1057 PF06342.12 ABX12606.1 - 0.061 12.3 0.3 0.063 12.3 0.3 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF4064 PF13273.6 ABX12608.1 - 0.015 15.6 0.2 0.019 15.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Polyketide_cyc2 PF10604.9 ABX12609.1 - 9.1e-15 55.2 0.0 1.1e-14 55.0 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4941 PF16299.5 ABX12609.1 - 0.04 13.2 0.6 0.049 12.9 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4941) Polyketide_cyc PF03364.20 ABX12609.1 - 0.055 13.7 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DUF4200 PF13863.6 ABX12610.1 - 0.00026 21.4 15.4 0.00026 21.4 15.4 4.0 2 1 3 5 5 5 1 Domain of unknown function (DUF4200) Spc7 PF08317.11 ABX12610.1 - 0.002 17.0 32.1 0.0032 16.4 2.0 2.9 3 0 0 3 3 3 2 Spc7 kinetochore protein FPP PF05911.11 ABX12610.1 - 0.032 12.4 40.5 0.1 10.8 6.6 2.4 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 ABX12610.1 - 0.066 13.8 35.8 0.15 12.6 1.5 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF4349 PF14257.6 ABX12610.1 - 0.085 12.3 7.7 0.2 11.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) Baculo_PEP_C PF04513.12 ABX12610.1 - 0.085 12.9 30.9 0.044 13.8 1.8 5.1 2 1 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3232 PF11554.8 ABX12610.1 - 0.2 12.1 0.2 0.2 12.1 0.2 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3232) RP-C_C PF11800.8 ABX12610.1 - 0.71 9.9 14.4 3.1 7.8 4.9 3.4 3 0 0 3 3 3 0 Replication protein C C-terminal region MCPsignal PF00015.21 ABX12610.1 - 1.3 8.8 24.0 0.035 13.9 1.8 4.7 2 2 1 5 5 5 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Rx_N PF18052.1 ABX12610.1 - 1.3 9.4 11.8 1.8 8.9 0.2 4.3 3 1 1 4 4 4 0 Rx N-terminal domain BLOC1_2 PF10046.9 ABX12610.1 - 1.9 8.9 36.3 1.4 9.3 0.5 6.3 3 3 3 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HD_3 PF13023.6 ABX12610.1 - 2.5 8.0 12.0 0.2 11.5 2.6 3.0 1 1 2 3 3 3 0 HD domain Prominin PF05478.11 ABX12610.1 - 3.2 5.6 32.7 1.2 7.0 6.3 2.9 1 1 2 3 3 3 0 Prominin Flagellin_N PF00669.20 ABX12610.1 - 3.5 7.7 17.9 0.28 11.3 6.6 3.4 3 1 0 3 3 3 0 Bacterial flagellin N-terminal helical region Hemocyanin_N PF03722.14 ABX12610.1 - 4.3 7.9 12.5 5.4 7.5 0.7 3.0 2 1 1 3 3 3 0 Hemocyanin, all-alpha domain Tup_N PF08581.10 ABX12610.1 - 4.6 7.6 25.4 1.8 9.0 0.4 5.0 3 2 2 5 5 5 0 Tup N-terminal UPF0449 PF15136.6 ABX12610.1 - 5.2 7.6 18.9 0.6 10.6 0.5 4.1 2 2 0 2 2 2 0 Uncharacterised protein family UPF0449 MscS_porin PF12795.7 ABX12610.1 - 5.8 6.4 19.6 1.4 8.5 1.1 2.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FliJ PF02050.16 ABX12610.1 - 7.6 6.8 13.8 24 5.2 2.8 4.1 2 2 2 4 4 4 0 Flagellar FliJ protein Prok-JAB PF14464.6 ABX12611.1 - 6.8e-12 45.2 0.0 1e-11 44.6 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain RadC PF04002.15 ABX12611.1 - 0.022 14.7 0.1 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 RadC-like JAB domain zf-NADH-PPase PF09297.11 ABX12612.1 - 0.048 13.3 0.7 0.048 13.3 0.7 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Prok-RING_4 PF14447.6 ABX12612.1 - 0.049 13.5 0.8 0.063 13.2 0.8 1.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Peptidase_C74 PF12387.8 ABX12612.1 - 0.17 11.4 1.5 0.23 10.9 1.5 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Zn_ribbon_recom PF13408.6 ABX12612.1 - 0.32 11.5 6.0 4.2 7.9 5.8 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf_UBZ PF18439.1 ABX12612.1 - 0.41 10.3 1.1 1.3 8.7 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 ABX12612.1 - 0.67 10.1 3.6 3.1 8.0 3.6 1.9 1 1 0 1 1 1 0 Zinc ribbon domain BPD_transp_1 PF00528.22 ABX12614.1 - 6.8e-25 87.9 9.2 6.8e-25 87.9 9.2 2.1 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 ABX12615.1 - 2.4e-38 131.7 18.0 2.4e-38 131.7 18.0 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3481 PF11980.8 ABX12615.1 - 0.16 11.7 1.8 11 5.8 0.1 2.7 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein ArsC PF03960.15 ABX12618.1 - 1.8e-13 50.3 0.2 2.2e-13 50.0 0.2 1.2 1 0 0 1 1 1 1 ArsC family Adenine_glyco PF03352.13 ABX12618.1 - 0.1 12.4 0.1 0.13 12.0 0.1 1.3 1 1 0 1 1 1 0 Methyladenine glycosylase UPF0154 PF03672.13 ABX12618.1 - 0.15 12.1 1.8 1.4 9.0 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0154) PriCT_1 PF08708.11 ABX12618.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) CarboxypepD_reg PF13620.6 ABX12619.1 - 1.2e-06 28.7 0.6 2.4e-06 27.7 0.6 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Dioxygenase_C PF00775.21 ABX12619.1 - 0.014 14.8 0.1 0.056 12.9 0.0 2.0 2 1 1 3 3 3 0 Dioxygenase PAC2 PF09754.9 ABX12621.1 - 2.9e-26 92.8 0.0 3.3e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 PAC2 family LpxI_N PF17930.1 ABX12621.1 - 0.049 13.5 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 LpxI N-terminal domain SNF2_N PF00176.23 ABX12622.1 - 3.3e-38 131.3 0.1 4.8e-38 130.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ABX12622.1 - 7.3e-12 45.6 1.4 3.6e-11 43.4 0.1 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ABX12622.1 - 6.4e-09 36.0 3.5 7.2e-09 35.9 0.0 2.6 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ABX12622.1 - 9.6e-06 25.5 0.1 3.8e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2802 PF10975.8 ABX12622.1 - 0.027 14.6 0.5 0.35 11.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) HTH_5 PF01022.20 ABX12623.1 - 0.013 15.4 0.1 0.03 14.2 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF3375 PF11855.8 ABX12623.1 - 0.04 12.9 0.6 0.056 12.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF2513 PF10711.9 ABX12623.1 - 0.048 14.0 0.7 0.14 12.5 0.1 2.1 2 1 1 3 3 3 0 Hypothetical protein (DUF2513) HTH_34 PF13601.6 ABX12623.1 - 0.077 13.2 0.1 0.28 11.4 0.1 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain SH3_14 PF18343.1 ABX12624.1 - 0.0075 16.4 1.7 0.015 15.4 1.7 1.4 1 0 0 1 1 1 1 Dda helicase SH3 domain Rab5-bind PF09311.11 ABX12624.1 - 0.0087 15.5 1.9 0.013 14.9 1.9 1.2 1 0 0 1 1 1 1 Rabaptin-like protein DUF148 PF02520.17 ABX12624.1 - 0.011 15.9 3.0 0.011 15.9 3.0 2.5 2 1 1 3 3 3 0 Domain of unknown function DUF148 Occludin_ELL PF07303.13 ABX12624.1 - 0.015 16.0 2.9 0.015 16.0 2.9 2.6 2 1 1 3 3 3 0 Occludin homology domain Snapin_Pallidin PF14712.6 ABX12624.1 - 0.1 13.0 1.2 3.6 8.1 0.2 2.4 2 1 0 2 2 2 0 Snapin/Pallidin CdvA PF18822.1 ABX12624.1 - 0.13 12.1 9.5 0.59 10.0 1.0 2.9 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Granin PF01271.17 ABX12624.1 - 0.14 11.0 3.4 0.2 10.5 3.2 1.3 1 1 0 1 1 1 0 Granin (chromogranin or secretogranin) DpnI_C PF17726.1 ABX12624.1 - 0.36 11.0 8.5 0.18 11.9 1.2 3.0 2 1 1 3 3 3 0 Dam-replacing HTH domain Fib_alpha PF08702.10 ABX12624.1 - 7.6 6.7 7.5 11 6.1 3.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sod_Fe_C PF02777.18 ABX12625.1 - 2.4e-39 133.6 1.4 3.4e-39 133.1 1.0 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ABX12625.1 - 1.3e-24 86.4 0.1 2.6e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain FAD-oxidase_C PF02913.19 ABX12630.1 - 2.7e-43 148.4 0.0 3.5e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ABX12630.1 - 1.9e-31 108.7 0.0 3.3e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ABX12630.1 - 0.0013 18.8 0.0 0.0034 17.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 ABX12630.1 - 0.0073 15.7 0.1 0.022 14.2 0.0 1.8 2 0 0 2 2 2 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF4113 PF13438.6 ABX12630.1 - 0.1 12.7 0.1 2.4 8.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4113) PDEase_I PF00233.19 ABX12631.1 - 0.0036 17.0 0.4 0.0036 17.0 0.4 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 ABX12631.1 - 0.0085 16.3 0.1 0.019 15.2 0.1 1.6 1 0 0 1 1 1 1 HD domain DnaJ PF00226.31 ABX12633.1 - 2.4e-22 78.8 3.8 2.4e-22 78.8 3.8 2.0 2 0 0 2 2 2 1 DnaJ domain O-antigen_lig PF13425.6 ABX12633.1 - 0.093 11.5 0.8 0.12 11.1 0.8 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein INSIG PF07281.12 ABX12633.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) Thioredoxin_8 PF13905.6 ABX12633.1 - 0.18 12.1 0.8 0.32 11.4 0.5 1.6 1 1 0 1 1 1 0 Thioredoxin-like HTH_AsnC-type PF13404.6 ABX12634.1 - 6.1e-13 48.4 0.9 1.1e-12 47.5 0.9 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 ABX12634.1 - 1.4e-12 47.3 0.2 2.3e-12 46.7 0.2 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 ABX12634.1 - 1.7e-12 46.7 2.2 6.4e-12 44.9 1.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 ABX12634.1 - 0.00022 21.1 1.1 0.0005 20.0 0.6 1.8 1 1 1 2 2 2 1 HTH domain HTH_50 PF18024.1 ABX12634.1 - 0.00034 20.1 0.1 0.013 15.1 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABX12634.1 - 0.00038 20.4 0.4 0.00075 19.4 0.2 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR PF01047.22 ABX12634.1 - 0.027 14.4 0.2 0.08 12.9 0.2 1.8 2 0 0 2 2 2 0 MarR family DDRGK PF09756.9 ABX12634.1 - 0.037 13.6 2.2 0.08 12.5 0.1 2.1 1 1 1 2 2 2 0 DDRGK domain MarR_2 PF12802.7 ABX12634.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 ABX12634.1 - 0.078 13.1 0.1 0.15 12.2 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 ABX12634.1 - 0.09 12.6 0.3 0.23 11.3 0.2 1.8 2 0 0 2 2 2 0 HTH DNA binding domain TPR_1 PF00515.28 ABX12635.1 - 7.9e-17 60.3 0.1 1.4e-10 40.5 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ABX12635.1 - 8.3e-16 56.8 0.1 4.2e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ABX12635.1 - 7.1e-11 41.6 0.0 6.4e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 TPR repeat TPR_19 PF14559.6 ABX12635.1 - 3.9e-10 40.1 0.0 4.3e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 ABX12635.1 - 4.4e-10 39.0 0.0 9.9e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 ABX12635.1 - 9.5e-10 37.8 0.0 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ABX12635.1 - 5.8e-09 36.4 0.0 6.7e-09 36.3 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ABX12635.1 - 1.7e-08 34.6 0.1 0.0022 18.7 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 ABX12635.1 - 9.6e-08 32.2 0.0 1.2e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 ABX12635.1 - 1.2e-07 31.6 0.7 3.2e-05 24.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 ABX12635.1 - 4.2e-07 30.0 0.0 4.9e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 ABX12635.1 - 1.1e-05 25.2 0.0 0.065 13.1 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ABX12635.1 - 0.00017 21.7 0.0 0.00019 21.6 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 ABX12635.1 - 0.0044 17.2 0.4 1.9 8.9 0.0 2.3 2 0 0 2 2 2 1 PPR repeat TPR_3 PF07720.12 ABX12635.1 - 0.0092 16.0 0.0 0.82 9.7 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 ABX12635.1 - 0.011 14.7 0.0 0.012 14.6 0.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 ABX12635.1 - 0.012 16.2 0.0 2.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 ABX12635.1 - 0.023 14.8 0.0 0.055 13.5 0.0 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) SRP_TPR_like PF17004.5 ABX12635.1 - 0.029 14.4 0.0 0.62 10.1 0.0 2.0 1 1 1 2 2 2 0 Putative TPR-like repeat Fis1_TPR_C PF14853.6 ABX12635.1 - 0.039 14.0 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 ABX12635.1 - 0.11 13.2 0.0 13 6.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 ABX12635.1 - 0.17 12.2 0.0 2.5 8.4 0.0 2.0 1 1 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 TPR_1 PF00515.28 ABX12636.1 - 8e-25 85.6 3.4 4.2e-07 29.5 0.2 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ABX12636.1 - 4.4e-21 73.2 1.4 5.4e-05 23.0 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 ABX12636.1 - 1.7e-17 62.1 4.1 0.00011 22.1 0.2 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 ABX12636.1 - 3.1e-17 62.0 0.3 0.00013 21.6 0.1 4.2 1 1 3 4 4 4 4 TPR repeat TPR_7 PF13176.6 ABX12636.1 - 1.3e-13 49.9 0.5 0.012 15.5 0.1 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 ABX12636.1 - 5e-13 49.4 0.9 3.9e-05 24.1 0.8 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 ABX12636.1 - 2.3e-12 46.6 0.2 0.074 13.9 0.0 4.1 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 ABX12636.1 - 1e-10 41.7 2.5 1.2e-05 25.4 0.4 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ABX12636.1 - 1.2e-10 41.0 1.2 0.00037 20.7 0.2 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ABX12636.1 - 1.9e-10 41.2 0.0 1.4e-05 25.7 0.0 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 ABX12636.1 - 3.7e-10 39.8 0.0 3.4e-05 23.9 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 ABX12636.1 - 2.5e-08 33.5 0.1 0.1 12.5 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 ABX12636.1 - 4.5e-08 33.2 1.5 0.063 13.9 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ABX12636.1 - 8.5e-06 25.9 0.9 0.00022 21.4 0.8 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 ABX12636.1 - 2.2e-05 24.4 2.4 0.92 9.6 0.2 4.1 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 ABX12636.1 - 4.5e-05 23.5 0.1 2.7 8.1 0.0 3.3 1 1 2 3 3 3 2 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 ABX12636.1 - 0.00016 21.6 1.5 3.2 7.8 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ABX12636.1 - 0.0017 18.4 1.4 2.7 8.1 0.1 3.9 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 ABX12636.1 - 0.0023 16.9 0.6 0.57 9.0 0.0 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 ABX12636.1 - 0.01 16.1 1.8 0.22 11.9 0.2 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 ABX12636.1 - 0.027 14.7 0.2 27 5.3 0.0 3.6 3 0 0 3 3 3 0 PPR repeat SRP_TPR_like PF17004.5 ABX12636.1 - 0.037 14.0 0.6 0.066 13.2 0.6 1.5 1 0 0 1 1 1 0 Putative TPR-like repeat zf-C2H2 PF00096.26 ABX12637.1 - 0.0012 19.2 1.0 0.0021 18.4 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ABX12637.1 - 0.0033 18.1 0.8 0.0033 18.1 0.8 1.5 2 0 0 2 2 2 1 C2H2-type zinc finger OTT_1508_deam PF14441.6 ABX12637.1 - 0.0045 17.0 0.1 0.0059 16.6 0.1 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-C2H2_2 PF12756.7 ABX12637.1 - 0.0069 16.7 1.2 0.0077 16.5 1.2 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ABX12637.1 - 0.016 15.5 1.1 0.016 15.5 1.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.14 ABX12637.1 - 0.028 14.2 1.7 0.052 13.4 1.7 1.5 1 1 0 1 1 1 0 Rad50 zinc hook motif DUF808 PF05661.12 ABX12637.1 - 0.17 10.9 0.2 0.19 10.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Radical_SAM PF04055.21 ABX12638.1 - 1.7e-16 61.1 0.1 3.3e-16 60.1 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily ATP-sulfurylase PF01747.17 ABX12638.1 - 0.0058 16.1 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase Fer4_14 PF13394.6 ABX12638.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Thiamine_BP PF01910.17 ABX12639.1 - 4.3e-25 87.5 1.9 4.7e-25 87.3 1.9 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Rnf-Nqr PF02508.14 ABX12640.1 - 0.024 14.6 0.1 0.032 14.2 0.1 1.2 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein DUF4345 PF14248.6 ABX12640.1 - 0.026 14.4 0.1 0.032 14.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) VitK2_biosynth PF02621.14 ABX12642.1 - 2.1e-79 266.8 0.0 2.4e-79 266.6 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis SIS PF01380.22 ABX12643.1 - 8.2e-08 32.2 2.4 0.0039 17.0 0.0 2.4 2 1 0 2 2 2 2 SIS domain GTP_EFTU PF00009.27 ABX12644.1 - 1.8e-60 203.8 0.8 3e-60 203.1 0.8 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ABX12644.1 - 1.3e-21 76.4 0.0 5.4e-21 74.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 ABX12644.1 - 4.1e-21 74.9 0.8 1e-20 73.6 0.8 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 ABX12644.1 - 1.3e-19 70.2 0.0 8.2e-19 67.6 0.0 2.3 1 1 1 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 ABX12644.1 - 6.9e-13 48.8 0.1 2.4e-12 47.1 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ABX12644.1 - 0.0056 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 ABX12644.1 - 0.01 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Ribosomal_L31 PF01197.18 ABX12646.1 - 0.032 14.4 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L31 Glycoprot_B_PH2 PF17417.2 ABX12646.1 - 0.062 13.6 0.0 0.077 13.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain Syntaxin_2 PF14523.6 ABX12648.1 - 0.0065 16.8 0.3 0.011 16.0 0.2 1.6 1 1 0 1 1 1 1 Syntaxin-like protein Baculo_PEP_C PF04513.12 ABX12648.1 - 0.1 12.6 1.0 0.25 11.4 1.0 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 ABX12648.1 - 0.64 10.5 4.3 8.5 6.9 2.5 2.8 2 1 0 2 2 2 0 Snapin/Pallidin Ycf66_N PF07444.11 ABX12649.1 - 0.03 14.4 0.2 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 Ycf66 protein N-terminus Methyltransf_3 PF01596.17 ABX12651.1 - 2.5e-35 121.6 1.2 3.1e-35 121.3 1.2 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ABX12651.1 - 7.2e-14 52.7 0.0 1e-13 52.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ABX12651.1 - 5.5e-07 29.6 1.1 5.6e-07 29.5 0.2 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ABX12651.1 - 6.7e-06 26.0 0.2 9.3e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 ABX12651.1 - 3.6e-05 23.6 0.3 4.6e-05 23.2 0.3 1.1 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltr_RsmB-F PF01189.17 ABX12651.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 ABX12651.1 - 0.0015 19.2 0.0 0.0037 17.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 ABX12651.1 - 0.016 14.9 1.3 0.033 13.9 1.3 1.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 ABX12651.1 - 0.018 14.6 0.3 0.034 13.7 0.3 1.4 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 ABX12651.1 - 0.021 15.5 0.0 0.048 14.3 0.0 1.7 2 1 0 2 2 2 0 Methyltransferase domain GCD14 PF08704.10 ABX12651.1 - 0.029 14.1 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Chordopox_A30L PF06015.12 ABX12651.1 - 0.034 14.0 1.3 0.034 14.0 1.3 2.3 3 1 0 3 3 3 0 Chordopoxvirus A30L protein MTS PF05175.14 ABX12651.1 - 0.037 13.6 0.1 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 ABX12651.1 - 0.06 13.0 3.3 0.082 12.5 0.7 2.0 1 1 1 2 2 2 0 Conserved hypothetical protein 95 P_C10 PF14974.6 ABX12651.1 - 7.7 6.7 7.3 8 6.6 1.2 2.7 2 1 0 2 2 2 0 Protein C10 Sulphotransf PF09037.10 ABX12652.1 - 0.054 13.0 0.2 0.089 12.3 0.2 1.4 1 1 0 1 1 1 0 Stf0 sulphotransferase AvrL567-A PF11529.8 ABX12652.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A U1snRNP70_N PF12220.8 ABX12654.1 - 0.018 15.7 3.7 0.022 15.4 3.7 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CUE PF02845.16 ABX12654.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 CUE domain SASA PF03629.18 ABX12654.1 - 0.11 12.1 0.2 0.12 12.0 0.2 1.0 1 0 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase DUF5615 PF18480.1 ABX12655.1 - 4e-14 52.1 0.4 9.4e-14 50.9 0.2 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF5615) Mut7-C PF01927.16 ABX12655.1 - 4.7e-06 26.8 0.1 4.9e-06 26.7 0.1 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain PIN_10 PF18478.1 ABX12655.1 - 5.7e-06 26.4 0.0 8.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 PIN like domain UPF0180 PF03698.13 ABX12655.1 - 0.002 18.3 0.0 0.0024 18.0 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0180) PIN_9 PF18477.1 ABX12655.1 - 0.026 14.8 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 PIN like domain DUF4411 PF14367.6 ABX12655.1 - 0.077 12.9 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Trm56 PF01994.16 ABX12655.1 - 0.097 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 Methyltr_RsmB-F PF01189.17 ABX12655.1 - 0.1 12.2 0.1 1.2 8.7 0.2 1.9 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F HTH_11 PF08279.12 ABX12656.1 - 0.0063 16.4 0.2 0.028 14.4 0.2 2.1 1 1 0 1 1 1 1 HTH domain EcoR124_C PF12008.8 ABX12656.1 - 0.012 15.3 0.3 0.012 15.3 0.3 1.9 2 1 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal DUF4844 PF16133.5 ABX12656.1 - 0.017 15.6 1.2 1 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4844) HTH_24 PF13412.6 ABX12656.1 - 0.019 14.5 0.8 0.019 14.5 0.8 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sec34 PF04136.15 ABX12656.1 - 0.024 14.5 2.0 0.095 12.6 2.0 1.9 1 1 0 1 1 1 0 Sec34-like family HTH_AsnC-type PF13404.6 ABX12656.1 - 0.062 13.1 0.1 0.062 13.1 0.1 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PIN_3 PF13470.6 ABX12656.1 - 0.1 13.4 0.0 0.14 12.9 0.0 1.4 1 1 0 1 1 1 0 PIN domain Prefoldin_2 PF01920.20 ABX12656.1 - 0.11 12.4 1.4 1.8 8.5 0.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF1132 PF06575.12 ABX12657.1 - 0.014 15.7 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Fis1_TPR_N PF14852.6 ABX12657.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat Reticulon PF02453.17 ABX12659.1 - 0.56 10.2 0.0 0.56 10.2 0.0 3.6 3 2 2 5 5 5 0 Reticulon DUF3290 PF11694.8 ABX12659.1 - 2.2 8.2 6.1 3.1 7.8 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) DUF202 PF02656.15 ABX12659.1 - 2.6 8.5 0.0 2.6 8.5 0.0 4.1 3 2 1 4 4 4 0 Domain of unknown function (DUF202) ETRAMP PF09716.10 ABX12659.1 - 4.9 7.3 7.1 2 8.6 0.0 3.0 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) TrkH PF02386.16 ABX12660.1 - 4.4e-19 68.3 26.6 7.4e-16 57.7 8.1 2.5 1 1 1 2 2 2 2 Cation transport protein CBS PF00571.28 ABX12660.1 - 1.2e-17 64.0 4.2 5.4e-10 39.6 0.1 2.4 2 0 0 2 2 2 2 CBS domain Ac76 PF05814.11 ABX12660.1 - 8.3 6.5 7.9 17 5.5 0.7 3.3 2 0 0 2 2 2 0 Orf76 (Ac76) DNase-RNase PF02577.14 ABX12661.1 - 1.3e-07 31.3 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease zf-trcl PF13451.6 ABX12665.1 - 0.0013 18.6 0.3 0.093 12.6 0.0 2.1 2 0 0 2 2 2 2 Probable zinc-ribbon domain Lar_restr_allev PF14354.6 ABX12665.1 - 0.0097 16.3 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar Gin PF10764.9 ABX12665.1 - 0.015 15.2 2.9 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin zf-RRPl_C4 PF17026.5 ABX12665.1 - 0.08 13.0 0.6 0.11 12.6 0.6 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF1297 PF06973.12 ABX12666.1 - 6e-73 244.4 0.1 8.9e-73 243.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.12 ABX12666.1 - 1.3e-47 160.8 0.0 2.8e-47 159.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) Flavoprotein PF02441.19 ABX12667.1 - 6.4e-29 100.7 0.3 7.6e-29 100.5 0.3 1.0 1 0 0 1 1 1 1 Flavoprotein DUF2888 PF11135.8 ABX12667.1 - 0.12 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) Polyketide_cyc PF03364.20 ABX12668.1 - 1.2e-06 28.8 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 ABX12668.1 - 0.0052 17.1 0.0 0.0065 16.7 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MttA_Hcf106 PF02416.16 ABX12669.1 - 6.5e-10 38.2 4.8 9.3e-10 37.7 4.8 1.3 1 1 0 1 1 1 1 mttA/Hcf106 family TatC PF00902.18 ABX12670.1 - 3.5e-51 174.0 14.0 4e-51 173.8 14.0 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) SmpA_OmlA PF04355.13 ABX12672.1 - 0.087 12.6 0.4 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 SmpA / OmlA family PurS PF02700.14 ABX12673.1 - 2.4e-19 69.2 0.5 2.7e-19 69.1 0.5 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase NleF_casp_inhib PF16809.5 ABX12673.1 - 0.016 15.1 0.5 0.02 14.8 0.5 1.1 1 0 0 1 1 1 0 NleF caspase inhibitor CBS PF00571.28 ABX12674.1 - 4.3e-28 97.5 1.9 6e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 CBS domain Acetyltransf_1 PF00583.25 ABX12674.1 - 0.025 14.8 0.0 5.1 7.4 0.0 2.1 1 1 1 2 2 2 0 Acetyltransferase (GNAT) family PSY3 PF16836.5 ABX12674.1 - 0.025 14.1 1.6 0.03 13.9 1.6 1.2 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description GATase_5 PF13507.6 ABX12675.1 - 2.2e-41 141.7 0.0 7.3e-41 140.0 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 ABX12675.1 - 2.7e-09 36.9 0.0 7.6e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 ABX12675.1 - 1.7e-08 34.4 0.0 3.1e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 ABX12675.1 - 6.9e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 ABX12675.1 - 0.0038 17.0 0.2 0.0099 15.6 0.2 1.7 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 ABX12675.1 - 0.023 14.5 0.0 0.058 13.2 0.0 1.6 2 0 0 2 2 2 0 SNO glutamine amidotransferase family AIRS_C PF02769.22 ABX12676.1 - 2.2e-47 161.1 0.1 1.5e-27 96.6 0.4 2.2 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 ABX12676.1 - 1.5e-38 131.3 0.0 3.6e-19 69.2 0.2 2.6 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain FGAR-AT_linker PF18072.1 ABX12676.1 - 8.1e-11 42.3 0.2 1.9e-10 41.1 0.2 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain GATase_6 PF13522.6 ABX12677.1 - 1.3e-14 54.5 0.0 1.2e-13 51.4 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ABX12677.1 - 6.4e-13 48.7 0.0 1.4e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 ABX12677.1 - 9.7e-10 38.2 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 ABX12677.1 - 2.3e-05 23.5 0.0 4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 ABX12677.1 - 0.00041 19.2 0.0 0.082 11.6 0.0 3.0 3 0 0 3 3 3 1 Glutamine amidotransferases class-II Dip PF17679.1 ABX12677.1 - 0.017 14.7 0.0 0.071 12.7 0.0 1.9 2 0 0 2 2 2 0 gp37/Dip protein Pribosyltran_N PF13793.6 ABX12677.1 - 0.16 11.9 0.1 0.38 10.7 0.1 1.6 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase NTP_transf_9 PF04248.12 ABX12678.1 - 1.2e-31 108.5 0.8 1.3e-31 108.3 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) SAICAR_synt PF01259.18 ABX12680.1 - 5.1e-70 236.0 0.2 6e-70 235.7 0.2 1.0 1 0 0 1 1 1 1 SAICAR synthetase HTH_20 PF12840.7 ABX12681.1 - 1.7e-09 37.6 0.1 3e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 ABX12681.1 - 3.1e-07 30.2 0.6 2.8e-06 27.1 0.6 2.2 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family FUR PF01475.19 ABX12681.1 - 0.00018 21.7 0.6 0.00038 20.6 0.6 1.7 1 1 0 1 1 1 1 Ferric uptake regulator family HTH_12 PF08461.10 ABX12681.1 - 0.00028 20.8 0.3 0.00054 19.8 0.3 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Type2_restr_D3 PF16902.5 ABX12681.1 - 0.0027 17.6 0.2 0.006 16.5 0.2 1.6 1 0 0 1 1 1 1 Type-2 restriction enzyme D3 domain Replic_Relax PF13814.6 ABX12681.1 - 0.038 14.0 0.3 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Replication-relaxation MeaB PF03308.16 ABX12681.1 - 0.086 11.8 0.3 0.47 9.4 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Putative_PNPOx PF01243.20 ABX12683.1 - 2.3e-15 56.5 0.0 3.4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 ABX12683.1 - 0.0052 16.8 0.0 0.01 15.8 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RcnB PF11776.8 ABX12683.1 - 0.033 14.2 0.2 0.08 13.0 0.0 1.8 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator DUF4352 PF11611.8 ABX12685.1 - 7e-09 36.0 0.1 9.6e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) DUF1330 PF07045.11 ABX12685.1 - 0.042 14.2 0.1 11 6.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) GNAT_acetyltran PF12746.7 ABX12685.1 - 0.23 11.0 2.2 4.7 6.7 0.8 2.1 1 1 1 2 2 2 0 GNAT acetyltransferase DUF2299 PF10061.9 ABX12687.1 - 1.3e-29 102.7 0.4 1.5e-29 102.5 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2299) DZR PF12773.7 ABX12688.1 - 0.0043 17.0 0.3 0.006 16.6 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon C1_4 PF07975.12 ABX12688.1 - 0.03 14.5 1.5 0.84 9.9 2.2 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain DUF35_N PF12172.8 ABX12688.1 - 0.1 12.5 1.4 1.3 8.9 0.0 2.4 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-IS66 PF13005.7 ABX12688.1 - 0.19 12.2 3.1 0.36 11.3 0.2 2.4 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-LYAR PF08790.11 ABX12688.1 - 0.34 10.9 2.8 11 6.0 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Ribosomal_L6 PF00347.23 ABX12690.1 - 4e-16 59.5 4.0 3.8e-07 30.7 0.4 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 DUF5625 PF18539.1 ABX12690.1 - 0.021 15.1 1.4 2.2 8.6 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5625) RL10P_insert PF17777.1 ABX12690.1 - 0.03 14.3 0.4 0.94 9.5 0.1 2.5 1 1 1 2 2 2 0 Insertion domain in 60S ribosomal protein L10P Ribosomal_S8 PF00410.19 ABX12691.1 - 2.5e-21 76.0 0.0 3e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S14 PF00253.21 ABX12692.1 - 3.9e-08 32.9 4.5 4.6e-08 32.7 4.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_L5_C PF00673.21 ABX12693.1 - 8.2e-20 70.8 0.0 1.5e-19 69.9 0.0 1.5 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ABX12693.1 - 3.5e-15 56.1 0.1 7.2e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_S4e PF00900.20 ABX12694.1 - 1.1e-17 63.7 2.0 1.1e-17 63.6 0.9 1.6 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.12 ABX12694.1 - 6.8e-13 48.5 1.8 1.2e-12 47.7 1.8 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 ABX12694.1 - 0.00014 21.7 0.4 0.00059 19.7 0.0 2.2 2 0 0 2 2 2 1 KOW motif S4 PF01479.25 ABX12694.1 - 0.00068 19.3 0.2 0.0021 17.7 0.1 2.0 2 0 0 2 2 2 1 S4 domain Ribosomal_L26 PF16906.5 ABX12695.1 - 3.5e-17 62.7 0.5 5.8e-17 61.9 0.5 1.4 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ABX12695.1 - 0.00046 20.0 0.8 0.00096 19.0 0.8 1.7 1 1 0 1 1 1 1 KOW motif Ribosomal_L14 PF00238.19 ABX12696.1 - 9.7e-33 112.8 0.3 1.1e-32 112.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_S17 PF00366.20 ABX12697.1 - 1e-16 60.7 0.2 1.4e-16 60.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 ABX12697.1 - 0.00016 22.0 0.3 0.00032 21.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal UPF0086 PF01868.16 ABX12698.1 - 1.2e-20 73.2 0.0 1.4e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_L29 PF00831.23 ABX12699.1 - 1.4e-12 47.3 3.4 1.8e-12 47.0 3.4 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein Ribosomal_S3_C PF00189.20 ABX12700.1 - 3.8e-19 69.0 1.3 9.8e-19 67.7 1.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ABX12700.1 - 4.8e-12 45.5 0.0 4.8e-12 45.5 0.0 2.7 3 0 0 3 3 3 1 KH domain ARA70 PF12489.8 ABX12700.1 - 0.55 10.4 3.3 1 9.5 3.3 1.5 1 0 0 1 1 1 0 Nuclear coactivator Ribosomal_L22 PF00237.19 ABX12701.1 - 1.5e-25 89.4 1.1 2e-25 89.0 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S19 PF00203.21 ABX12702.1 - 8.9e-27 92.8 0.3 1.1e-26 92.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L23 PF00276.20 ABX12703.1 - 1.4e-14 54.2 2.2 2.5e-14 53.4 2.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L23 DNA_mis_repair PF01119.19 ABX12703.1 - 0.0014 18.3 0.1 0.002 17.8 0.1 1.4 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain NOP5NT PF08156.13 ABX12703.1 - 0.027 14.8 0.2 0.038 14.4 0.2 1.4 1 1 0 1 1 1 0 NOP5NT (NUC127) domain Ribosomal_L4 PF00573.22 ABX12704.1 - 2.3e-45 154.7 0.4 2.7e-45 154.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L3 PF00297.22 ABX12705.1 - 3.5e-70 236.8 0.4 6.6e-70 235.9 0.4 1.4 1 1 0 1 1 1 1 Ribosomal protein L3 Methyltrn_RNA_3 PF02598.17 ABX12706.1 - 7e-51 173.4 0.0 8e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 ABX12706.1 - 0.0064 16.7 0.0 0.99 9.6 0.0 2.2 2 0 0 2 2 2 2 SpoU rRNA Methylase family S1 PF00575.23 ABX12706.1 - 0.11 12.9 1.6 0.55 10.6 0.5 2.4 2 0 0 2 2 2 0 S1 RNA binding domain Proteasome PF00227.26 ABX12707.1 - 5e-55 185.9 0.2 6.5e-55 185.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ABX12707.1 - 3.6e-14 52.1 0.7 1.4e-13 50.2 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF371 PF04027.13 ABX12708.1 - 3.9e-50 169.3 0.1 4.3e-50 169.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF371) TPK_B1_binding PF04265.14 ABX12709.1 - 0.022 14.5 0.1 0.12 12.1 0.0 2.2 3 0 0 3 3 3 0 Thiamin pyrophosphokinase, vitamin B1 binding domain WbqC PF08889.11 ABX12709.1 - 0.059 13.3 0.8 0.065 13.1 0.7 1.3 1 1 0 1 1 1 0 WbqC-like protein family Copper-bind PF00127.20 ABX12711.1 - 9.1e-10 38.9 0.0 4.6e-09 36.6 0.0 2.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family THDPS_N_2 PF14805.6 ABX12711.1 - 1.2e-05 25.5 0.4 5.1 7.4 0.0 4.6 4 1 1 5 5 5 2 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF2089 PF09862.9 ABX12711.1 - 1.5e-05 25.0 0.3 5.2 7.1 0.0 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF2089) GatB_Yqey PF02637.18 ABX12711.1 - 5.9e-05 23.0 3.2 2.4 8.0 0.1 4.6 3 2 0 4 4 4 1 GatB domain ThrE PF06738.12 ABX12711.1 - 0.00014 21.3 0.0 9.1 5.6 0.0 3.8 4 0 0 4 4 4 3 Putative threonine/serine exporter DUF2150 PF09920.9 ABX12711.1 - 0.00021 21.4 0.8 3.1 7.8 0.2 3.9 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2150) AF0941-like PF14591.6 ABX12711.1 - 0.0022 18.5 8.7 3.7 8.1 0.4 4.2 1 1 2 4 4 4 1 AF0941-like Mistic PF11458.8 ABX12711.1 - 0.0074 16.2 1.3 16 5.5 0.0 3.9 3 0 0 3 3 3 0 Membrane-integrating protein Mistic DUF1160 PF06648.11 ABX12711.1 - 0.011 15.8 0.2 2.7 8.0 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1160) AAA_29 PF13555.6 ABX12711.1 - 0.036 13.8 0.1 14 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0175 PF03683.13 ABX12711.1 - 0.04 13.6 0.0 43 3.9 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0175) PMBR PF09373.10 ABX12711.1 - 0.075 13.2 0.1 1.7e+02 2.6 0.0 3.9 4 0 0 4 4 4 0 Pseudomurein-binding repeat Exonuc_VII_S PF02609.16 ABX12711.1 - 0.093 12.8 0.4 46 4.2 0.0 3.6 3 0 0 3 3 3 0 Exonuclease VII small subunit SSV1_ORF_D-335 PF07935.11 ABX12711.1 - 0.32 11.3 1.7 85 3.6 0.0 3.8 4 1 0 4 4 3 0 ORF D-335-like protein Snf7 PF03357.21 ABX12712.1 - 1.1e-06 28.3 1.4 1.9e-06 27.6 1.4 1.4 1 1 0 1 1 1 1 Snf7 DUF1073 PF06381.11 ABX12712.1 - 0.026 13.3 0.6 0.033 13.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) DUF2073 PF09846.9 ABX12712.1 - 0.2 11.6 1.8 6.8 6.6 0.1 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2073) Thioredoxin_10 PF17991.1 ABX12713.1 - 2.8e-33 115.5 0.1 4.1e-33 114.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin like C-terminal domain AhpC-TSA PF00578.21 ABX12713.1 - 3.6e-08 33.3 0.0 5.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ABX12713.1 - 5.1e-07 29.5 0.0 9.5e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 ABX12713.1 - 0.0051 17.1 0.1 0.011 16.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like DsbD PF02683.15 ABX12714.1 - 8.2e-48 163.1 18.1 9.6e-48 162.9 18.1 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 ABX12714.1 - 3.7e-05 23.8 15.1 5.1e-05 23.3 15.1 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF2116 PF09889.9 ABX12714.1 - 1.2 9.2 2.5 9.3 6.3 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF2781 PF10914.8 ABX12714.1 - 1.8 8.9 7.1 1.3 9.4 4.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2781) Baculo_11_kDa PF06143.11 ABX12714.1 - 9.3 5.9 9.4 2 8.1 0.2 2.6 3 0 0 3 3 3 0 Baculovirus 11 kDa family Aminotran_1_2 PF00155.21 ABX12715.1 - 1.2e-57 195.7 0.0 1.4e-57 195.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ABX12715.1 - 2.3e-05 23.1 0.3 3.9e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ABX12715.1 - 0.0071 15.3 0.2 0.011 14.7 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ABX12715.1 - 0.0075 15.6 0.1 0.017 14.4 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 ABX12715.1 - 0.038 12.7 0.1 1.4 7.6 0.1 2.1 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Peptidase_M10 PF00413.24 ABX12716.1 - 5.7e-10 39.3 0.4 1.3e-09 38.1 0.4 1.6 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 ABX12716.1 - 0.0078 15.8 0.1 0.01 15.5 0.1 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.9 ABX12716.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 ABX12716.1 - 0.015 15.8 0.1 0.022 15.3 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 ABX12716.1 - 0.033 13.4 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 ABX12716.1 - 0.049 13.8 0.3 0.083 13.0 0.3 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 ABX12716.1 - 0.13 11.9 2.6 0.37 10.4 2.6 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Radical_SAM PF04055.21 ABX12717.1 - 1.2e-18 68.1 0.9 2.6e-18 66.9 0.5 1.7 2 0 0 2 2 2 1 Radical SAM superfamily BATS PF06968.13 ABX12717.1 - 1.3e-12 47.6 0.0 2.9e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Aminotran_3 PF00202.21 ABX12718.1 - 4.2e-100 335.3 0.2 4.7e-100 335.1 0.2 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 ABX12718.1 - 0.0033 16.8 0.0 0.0067 15.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase AAA_26 PF13500.6 ABX12719.1 - 1.2e-40 139.5 0.2 1.4e-40 139.3 0.2 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ABX12719.1 - 5.2e-13 49.2 0.0 9.1e-13 48.4 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 ABX12719.1 - 2.3e-05 24.0 3.4 0.029 13.8 0.1 2.6 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase DUF1611 PF07755.11 ABX12719.1 - 0.00014 21.2 0.4 0.015 14.6 0.3 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF1611_C) P-loop domain ArsA_ATPase PF02374.15 ABX12719.1 - 0.1 11.7 1.6 5.7 6.0 0.1 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase TrmB PF01978.19 ABX12720.1 - 0.00022 21.0 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HxlR PF01638.17 ABX12720.1 - 0.00089 19.1 0.0 0.0011 18.8 0.0 1.0 1 0 0 1 1 1 1 HxlR-like helix-turn-helix TFIIE_alpha PF02002.17 ABX12720.1 - 0.0009 19.1 0.1 0.00095 19.0 0.1 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit FANCI_S1-cap PF14674.6 ABX12720.1 - 0.018 15.1 0.1 0.024 14.7 0.1 1.3 1 0 0 1 1 1 0 FANCI solenoid 1 cap Snf7 PF03357.21 ABX12720.1 - 0.032 13.8 1.2 0.045 13.3 1.2 1.3 1 1 0 1 1 1 0 Snf7 APG17 PF04108.12 ABX12720.1 - 0.041 13.0 0.1 0.041 13.0 0.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 HTH_45 PF14947.6 ABX12720.1 - 0.043 13.8 0.2 0.058 13.4 0.2 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix SMC_ScpB PF04079.16 ABX12720.1 - 0.059 13.0 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB MarR PF01047.22 ABX12720.1 - 0.071 13.1 0.1 0.087 12.8 0.1 1.1 1 0 0 1 1 1 0 MarR family DUF4194 PF13835.6 ABX12720.1 - 0.095 12.4 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) Band_7 PF01145.25 ABX12721.1 - 1.4e-25 90.3 6.7 2.4e-25 89.6 6.7 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF4472 PF14739.6 ABX12721.1 - 1.1 10.0 5.7 0.84 10.4 0.9 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) Thioredoxin_3 PF13192.6 ABX12722.1 - 0.013 15.5 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Phage_holin_6_1 PF09682.10 ABX12722.1 - 0.031 14.7 0.3 0.048 14.1 0.3 1.3 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Orthopox_A36R PF05950.11 ABX12722.1 - 0.042 14.0 0.2 0.047 13.9 0.2 1.0 1 0 0 1 1 1 0 Orthopoxvirus A36R protein FB_lectin PF07367.11 ABX12722.1 - 0.2 11.6 1.9 0.24 11.3 1.9 1.2 1 0 0 1 1 1 0 Fungal fruit body lectin DUF3139 PF11337.8 ABX12722.1 - 0.21 12.2 10.9 2 9.1 10.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) NapE PF06796.11 ABX12722.1 - 3.2 7.4 5.2 1.1 8.8 2.0 1.8 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE DUF3919 PF13057.6 ABX12723.1 - 0.0017 18.0 2.5 0.053 13.1 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3919) Lipase_GDSL_3 PF14606.6 ABX12723.1 - 0.15 12.2 0.7 0.34 11.0 0.1 1.7 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family IL31 PF15209.6 ABX12723.1 - 0.16 11.7 4.0 0.11 12.3 0.8 2.2 2 1 0 2 2 2 0 Interleukin 31 IMCp PF12314.8 ABX12723.1 - 0.28 11.5 7.7 0.12 12.7 2.9 2.1 2 0 0 2 2 2 0 Inner membrane complex protein HMG_CoA_synt_C PF08540.10 ABX12724.1 - 3.6e-34 118.7 0.1 5.6e-34 118.1 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 ABX12724.1 - 2.5e-29 102.3 0.2 4.2e-29 101.6 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Thioredoxin_4 PF13462.6 ABX12725.1 - 5.7e-28 98.1 0.0 7.6e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ABX12725.1 - 8.2e-15 55.1 0.0 1.7e-13 50.8 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ABX12725.1 - 0.0038 17.7 0.0 0.0074 16.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain DUF5314 PF17241.2 ABX12725.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5314) Ost4 PF10215.9 ABX12725.1 - 1.1 9.1 2.9 2.7 7.9 2.9 1.6 1 0 0 1 1 1 0 Oligosaccaryltransferase FAM92 PF06730.11 ABX12727.1 - 0.0063 15.9 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 2 FAM92 protein DapB_N PF01113.20 ABX12727.1 - 0.017 15.3 0.0 0.05 13.7 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 ABX12727.1 - 0.13 12.9 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF21 PF01595.20 ABX12728.1 - 3.7e-50 170.0 0.0 5.9e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 ABX12728.1 - 5.5e-18 64.8 1.4 5.5e-18 64.8 1.4 2.4 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 ABX12728.1 - 5.7e-15 55.5 0.2 2.1e-06 28.1 0.1 2.7 2 0 0 2 2 2 2 CBS domain PALP PF00291.25 ABX12729.1 - 5.8e-47 160.5 0.0 7.4e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PK_C PF02887.16 ABX12729.1 - 0.21 11.8 1.5 2.4 8.4 0.6 2.2 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain GRIP PF01465.20 ABX12730.1 - 0.035 14.0 0.2 0.071 13.0 0.2 1.5 1 0 0 1 1 1 0 GRIP domain GIT1_C PF12205.8 ABX12731.1 - 0.0043 17.2 0.2 0.005 16.9 0.2 1.1 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term IFT20 PF14931.6 ABX12731.1 - 0.012 15.7 1.6 2.4 8.3 0.1 2.1 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Fib_alpha PF08702.10 ABX12731.1 - 0.028 14.6 0.9 0.64 10.2 0.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SesA PF17107.5 ABX12731.1 - 0.034 14.3 0.5 0.041 14.1 0.5 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 ABX12731.1 - 0.068 13.7 1.3 5.6 7.5 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1993 PF09351.10 ABX12731.1 - 0.089 12.9 0.1 0.15 12.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) YtxH PF12732.7 ABX12731.1 - 0.29 11.7 3.5 1.5 9.5 0.0 2.2 2 0 0 2 2 2 0 YtxH-like protein Trypan_PARP PF05887.11 ABX12732.1 - 0.00064 19.7 68.3 1.8e+04 -5.0 68.3 2.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 ABX12732.1 - 0.11 13.0 73.8 1.8e+04 -13.1 73.8 2.5 1 1 0 1 1 1 0 TonB polyproline region Hjc PF01870.18 ABX12733.1 - 2.9e-05 24.0 0.0 4.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) APG6_N PF17675.1 ABX12734.1 - 0.02 15.4 4.7 0.023 15.2 4.7 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF35_N PF12172.8 ABX12736.1 - 0.17 11.8 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Thiolase_C PF02803.18 ABX12737.1 - 1.3e-13 50.6 0.7 3.6e-13 49.2 0.3 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 ABX12737.1 - 1.1e-10 41.4 1.8 2.8e-09 36.7 0.5 2.8 1 1 1 2 2 2 1 Thiolase, N-terminal domain Dodecin PF07311.12 ABX12737.1 - 0.0022 18.2 0.3 0.0053 17.0 0.3 1.5 1 0 0 1 1 1 1 Dodecin Ketoacyl-synt_C PF02801.22 ABX12737.1 - 0.0094 16.0 3.2 0.049 13.6 0.9 2.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 ABX12737.1 - 0.019 14.6 0.0 0.06 12.9 0.0 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ABX12737.1 - 0.05 13.5 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Bac_luciferase PF00296.20 ABX12738.1 - 6.4e-65 219.6 0.0 7.1e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF5572 PF17733.1 ABX12738.1 - 0.068 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5572) HMGL-like PF00682.19 ABX12738.1 - 0.1 12.1 0.2 5.4 6.5 0.1 2.3 2 1 0 2 2 2 0 HMGL-like NTP_transferase PF00483.23 ABX12739.1 - 9.4e-31 107.3 0.3 1.3e-30 106.8 0.3 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ABX12739.1 - 1.2e-11 45.2 0.0 1.6e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 ABX12739.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CspB_prodomain PF18425.1 ABX12739.1 - 0.032 14.2 0.6 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 Csp protease B prodomain DUF3188 PF11384.8 ABX12741.1 - 4.7 7.0 12.3 0.12 12.1 4.0 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3188) DUF4418 PF14387.6 ABX12741.1 - 6.6 7.0 8.8 0.54 10.5 2.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4418) ATP-grasp PF02222.22 ABX12742.1 - 3.2e-59 199.3 0.1 5e-59 198.7 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 ABX12742.1 - 1.3e-14 53.6 0.0 2.5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 ABX12742.1 - 1.6e-09 37.6 0.2 3.9e-09 36.3 0.2 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 ABX12742.1 - 1.7e-06 28.2 0.1 3.4e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain DUF1297 PF06973.12 ABX12742.1 - 0.0023 17.5 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) ATP-grasp_2 PF08442.10 ABX12742.1 - 0.0042 16.7 1.3 1.6 8.2 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 ABX12742.1 - 0.012 15.4 0.1 0.025 14.3 0.1 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 2-Hacid_dh_C PF02826.19 ABX12742.1 - 0.04 13.3 0.1 0.088 12.2 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 ABX12742.1 - 0.085 13.1 0.4 0.68 10.2 0.0 2.7 3 2 1 4 4 4 0 TrkA-N domain Pyr_redox_2 PF07992.14 ABX12742.1 - 0.11 11.7 0.1 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 ABX12742.1 - 0.14 12.8 0.3 0.72 10.5 0.1 2.3 2 1 0 2 2 2 0 PglD N-terminal domain Trp_halogenase PF04820.14 ABX12742.1 - 0.18 10.6 0.1 0.29 9.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AIRC PF00731.20 ABX12743.1 - 2.5e-59 199.1 0.4 3.2e-59 198.7 0.4 1.1 1 0 0 1 1 1 1 AIR carboxylase PrpR_N PF06506.11 ABX12743.1 - 0.0024 17.5 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 Propionate catabolism activator Asp_Glu_race PF01177.22 ABX12743.1 - 0.023 14.6 0.1 0.033 14.0 0.1 1.5 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase Bac_luciferase PF00296.20 ABX12743.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase PALP PF00291.25 ABX12744.1 - 2.4e-86 289.8 2.6 4.2e-86 289.0 2.0 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ACT_4 PF13291.6 ABX12744.1 - 0.00017 22.1 0.3 0.00048 20.7 0.3 1.7 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 ABX12744.1 - 0.0011 18.7 0.1 0.0028 17.4 0.1 1.7 1 0 0 1 1 1 1 ACT domain Thr_dehydrat_C PF00585.18 ABX12744.1 - 0.003 17.3 0.0 0.027 14.2 0.0 2.2 2 0 0 2 2 2 1 C-terminal regulatory domain of Threonine dehydratase CPSase_L_D3 PF02787.19 ABX12745.1 - 0.2 12.0 2.9 0.2 12.0 0.5 2.0 2 1 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Guanylate_cyc PF00211.20 ABX12746.1 - 1.3e-16 60.8 0.1 1.9e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DivIC PF04977.15 ABX12747.1 - 0.0041 16.8 0.9 0.0041 16.8 0.9 1.5 2 0 0 2 2 2 1 Septum formation initiator bZIP_1 PF00170.21 ABX12747.1 - 0.2 11.8 7.1 0.39 10.9 7.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor Prp19 PF08606.11 ABX12747.1 - 0.58 10.2 3.3 0.46 10.5 0.9 1.9 2 0 0 2 2 2 0 Prp19/Pso4-like YabA PF06156.13 ABX12747.1 - 1 10.0 5.7 0.52 11.0 2.3 2.0 2 1 0 2 2 2 0 Initiation control protein YabA Glyoxalase_2 PF12681.7 ABX12749.1 - 1.3e-09 38.0 0.0 1.6e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 ABX12749.1 - 2.7e-09 37.3 0.0 5.4e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABX12749.1 - 0.00013 22.7 0.0 0.00016 22.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ABX12749.1 - 0.014 15.7 0.0 0.69 10.2 0.0 2.2 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AsnC_trans_reg PF01037.21 ABX12750.1 - 5.5e-08 32.7 0.0 6e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GYD PF08734.11 ABX12750.1 - 0.013 15.4 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 GYD domain ACT_4 PF13291.6 ABX12750.1 - 0.033 14.8 0.5 0.082 13.5 0.5 1.6 1 1 1 2 2 2 0 ACT domain YjgF_endoribonc PF14588.6 ABX12750.1 - 0.088 12.9 0.0 0.091 12.9 0.0 1.0 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease AsnC_trans_reg PF01037.21 ABX12751.1 - 0.0066 16.4 0.5 0.012 15.6 0.5 1.5 1 1 0 1 1 1 1 Lrp/AsnC ligand binding domain PTPS PF01242.19 ABX12751.1 - 0.095 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Cob_adeno_trans PF01923.18 ABX12754.1 - 7.1e-54 182.4 0.0 7.9e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF1931 PF09123.11 ABX12754.1 - 0.016 15.3 0.1 0.031 14.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) PC_rep PF01851.22 ABX12754.1 - 0.063 13.7 0.0 0.2 12.2 0.0 1.8 2 0 0 2 2 2 0 Proteasome/cyclosome repeat HD_3 PF13023.6 ABX12755.1 - 5.2e-39 133.8 1.3 6.2e-39 133.6 1.3 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 ABX12755.1 - 5.1e-18 65.5 2.3 7e-18 65.0 2.3 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 ABX12755.1 - 2.1e-06 27.9 0.2 4.9e-06 26.8 0.2 1.6 1 1 0 1 1 1 1 HD domain HEPN_Toprim_N PF18871.1 ABX12755.1 - 0.049 13.6 0.9 0.087 12.7 0.6 1.4 1 1 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 BTG PF07742.12 ABX12755.1 - 0.073 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 BTG family HDOD PF08668.12 ABX12755.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 HDOD domain UPF0515 PF15135.6 ABX12755.1 - 0.19 11.0 0.2 0.24 10.7 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 TINF2_N PF14973.6 ABX12757.1 - 0.065 13.6 0.1 0.086 13.2 0.1 1.2 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus PepSY_like PF11396.8 ABX12757.1 - 0.12 12.9 0.3 0.12 12.9 0.3 2.0 1 1 1 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like Saccharop_dh_N PF04455.12 ABX12759.1 - 2.4e-35 120.9 0.2 7.8e-35 119.3 0.3 1.8 2 0 0 2 2 2 1 LOR/SDH bifunctional enzyme conserved region Citrate_bind PF16114.5 ABX12759.1 - 0.0013 18.2 0.3 0.033 13.7 0.0 2.8 2 1 1 3 3 3 1 ATP citrate lyase citrate-binding TPP_enzyme_M PF00205.22 ABX12759.1 - 0.0016 18.2 0.4 0.087 12.6 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DS PF01916.17 ABX12759.1 - 0.0047 16.2 4.0 0.032 13.5 0.2 3.1 2 1 1 4 4 4 1 Deoxyhypusine synthase PriA_C PF18074.1 ABX12759.1 - 0.13 13.0 0.5 1.3 9.9 0.2 2.6 3 0 0 3 3 3 0 Primosomal protein N C-terminal domain SHOCT PF09851.9 ABX12760.1 - 0.0015 18.2 0.1 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.12 ABX12760.1 - 0.012 15.6 0.6 0.021 14.8 0.1 1.7 2 0 0 2 2 2 0 Gas vesicle protein G RIC3 PF15361.6 ABX12760.1 - 0.015 15.7 0.1 0.018 15.4 0.1 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Agglutinin_C PF18021.1 ABX12760.1 - 0.074 13.6 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Agglutinin C-terminal Aminotran_1_2 PF00155.21 ABX12761.1 - 1e-39 136.8 0.0 1.3e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II XAP5 PF04921.14 ABX12761.1 - 0.07 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator Beta_elim_lyase PF01212.21 ABX12761.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase AMP-binding PF00501.28 ABX12762.1 - 1.9e-80 270.6 0.0 2.3e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABX12762.1 - 2.5e-15 57.2 0.0 6e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ABX12762.1 - 3.5e-11 42.8 0.7 7.8e-11 41.7 0.7 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus GatB_N PF02934.15 ABX12764.1 - 7.6e-92 307.6 0.0 1.2e-91 306.9 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 ABX12764.1 - 5.8e-33 113.9 4.3 1.1e-32 113.0 4.3 1.5 1 0 0 1 1 1 1 GatB domain TMP_2 PF06791.13 ABX12764.1 - 0.012 15.3 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 Prophage tail length tape measure protein SpoVIF PF14069.6 ABX12764.1 - 0.085 12.6 0.7 7.6 6.4 0.0 3.0 2 1 1 3 3 3 0 Stage VI sporulation protein F Amidase PF01425.21 ABX12765.1 - 7.5e-137 457.0 0.1 8.5e-137 456.8 0.1 1.0 1 0 0 1 1 1 1 Amidase Glu-tRNAGln PF02686.15 ABX12766.1 - 0.0085 16.4 3.6 0.012 15.9 0.3 2.0 1 1 1 2 2 2 1 Glu-tRNAGln amidotransferase C subunit tRNA-synt_2 PF00152.20 ABX12767.1 - 1.7e-78 263.9 0.0 2.1e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ABX12767.1 - 8.9e-12 44.8 0.1 1.6e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ABX12767.1 - 0.048 13.1 0.1 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF1297 PF06973.12 ABX12768.1 - 2.5e-74 248.9 0.2 3.3e-74 248.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.12 ABX12768.1 - 3.6e-46 156.1 0.0 5.6e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) ATP-grasp_3 PF02655.14 ABX12768.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain BPD_transp_1 PF00528.22 ABX12769.1 - 1.1e-19 70.9 14.5 1.1e-19 70.9 14.5 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component MotA_ExbB PF01618.16 ABX12769.1 - 0.052 13.3 0.2 0.052 13.3 0.2 2.6 4 0 0 4 4 4 0 MotA/TolQ/ExbB proton channel family Tcf25 PF04910.14 ABX12769.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional repressor TCF25 ABC_tran PF00005.27 ABX12770.1 - 2.8e-34 118.6 0.2 4e-34 118.1 0.2 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ABX12770.1 - 2.2e-07 30.5 3.1 1.6e-05 24.5 3.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ABX12770.1 - 4e-06 26.9 1.1 0.022 14.6 0.4 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABX12770.1 - 5.9e-06 25.9 0.1 1.2e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.7 ABX12770.1 - 0.0013 17.8 2.8 0.0032 16.5 2.7 1.6 1 1 0 1 1 1 1 AAA-like domain ATPase PF06745.13 ABX12770.1 - 0.0043 16.4 0.6 1.6 8.0 0.1 2.2 2 0 0 2 2 2 2 KaiC AAA_24 PF13479.6 ABX12770.1 - 0.0059 16.4 1.2 0.22 11.2 0.2 2.4 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ABX12770.1 - 0.0067 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 ABX12770.1 - 0.0069 16.3 1.8 0.01 15.7 0.5 2.0 2 1 1 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 ABX12770.1 - 0.0089 16.3 2.1 0.1 12.9 2.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ABX12770.1 - 0.029 14.9 0.8 0.052 14.0 0.8 1.7 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 ABX12770.1 - 0.041 14.0 0.7 0.12 12.5 0.2 2.0 2 1 0 2 2 2 0 Helicase HerA, central domain G-alpha PF00503.20 ABX12770.1 - 0.043 13.0 0.3 0.067 12.3 0.3 1.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 ABX12770.1 - 0.053 13.9 0.1 0.16 12.3 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 ABX12770.1 - 0.073 13.2 0.4 0.11 12.6 0.4 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 ABX12770.1 - 0.09 11.9 1.3 3.3 6.8 0.2 2.4 3 0 0 3 3 3 0 NB-ARC domain Dynamin_N PF00350.23 ABX12770.1 - 0.1 12.6 0.8 3.1 7.8 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_5 PF07728.14 ABX12770.1 - 0.1 12.6 0.3 0.6 10.1 0.0 2.2 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Roc PF08477.13 ABX12770.1 - 0.11 12.7 0.2 0.43 10.8 0.1 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Phosphonate-bd PF12974.7 ABX12771.1 - 8e-44 150.1 0.2 1e-43 149.7 0.2 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 ABX12771.1 - 4.3e-05 23.0 0.0 8.9e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 ABX12771.1 - 0.0019 17.9 0.3 0.032 13.9 0.0 2.7 3 1 1 4 4 4 1 NMT1-like family Transferrin PF00405.17 ABX12771.1 - 0.031 13.4 0.0 0.081 12.1 0.0 1.6 1 1 1 2 2 2 0 Transferrin NMT1 PF09084.11 ABX12771.1 - 0.092 12.7 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 NMT1/THI5 like TrmB PF01978.19 ABX12772.1 - 2.2e-06 27.5 0.1 3.6e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 ABX12772.1 - 0.00017 21.4 0.1 0.00038 20.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_7 PF02796.15 ABX12772.1 - 0.00019 21.4 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 ABX12772.1 - 0.00051 19.9 0.1 0.00085 19.2 0.1 1.5 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 ABX12772.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_20 PF12840.7 ABX12772.1 - 0.0014 18.6 0.0 0.002 18.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1492 PF07374.11 ABX12772.1 - 0.003 17.7 0.2 0.0044 17.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1492) Fe_dep_repress PF01325.19 ABX12772.1 - 0.0032 17.6 0.1 0.0053 16.9 0.1 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Mga PF05043.13 ABX12772.1 - 0.004 17.7 0.8 0.0081 16.7 0.6 1.7 1 1 1 2 2 2 1 Mga helix-turn-helix domain HTH_24 PF13412.6 ABX12772.1 - 0.0046 16.5 0.5 0.0085 15.6 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding FUR PF01475.19 ABX12772.1 - 0.0065 16.6 0.1 0.0093 16.1 0.1 1.4 1 1 0 1 1 1 1 Ferric uptake regulator family Sigma70_r4_2 PF08281.12 ABX12772.1 - 0.0099 15.5 0.1 0.018 14.7 0.1 1.5 1 1 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 ABX12772.1 - 0.017 15.0 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_40 PF14493.6 ABX12772.1 - 0.017 15.6 0.4 0.026 14.9 0.2 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 ABX12772.1 - 0.023 14.5 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_22 PF13309.6 ABX12772.1 - 0.031 14.4 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 HTH domain DDE_Tnp_2 PF04693.12 ABX12772.1 - 0.034 13.4 0.1 0.041 13.1 0.1 1.1 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 HTH_36 PF13730.6 ABX12772.1 - 0.056 13.4 0.3 0.11 12.5 0.2 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 ABX12772.1 - 0.089 13.0 0.1 0.098 12.8 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_17 PF12728.7 ABX12772.1 - 0.13 12.5 0.1 0.2 11.9 0.1 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 ABX12773.1 - 2.6e-07 30.6 0.0 3.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 ABX12773.1 - 1.3e-05 25.0 0.3 2.9e-05 23.8 0.3 1.7 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 ABX12773.1 - 1.3e-05 25.0 0.3 1.6e-05 24.7 0.3 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit DUF742 PF05331.11 ABX12773.1 - 0.0013 18.6 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_IclR PF09339.10 ABX12773.1 - 0.0047 16.7 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.12 ABX12773.1 - 0.0064 16.4 0.2 0.012 15.5 0.2 1.5 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 ABX12773.1 - 0.0074 16.1 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 ABX12773.1 - 0.016 15.0 0.1 0.032 14.1 0.1 1.6 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family Mga PF05043.13 ABX12773.1 - 0.021 15.4 0.3 0.16 12.5 0.1 2.1 1 1 1 2 2 2 0 Mga helix-turn-helix domain PadR PF03551.14 ABX12773.1 - 0.034 14.1 0.2 0.084 12.8 0.1 1.6 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family YycC PF14174.6 ABX12773.1 - 0.071 12.9 0.1 0.19 11.6 0.1 1.8 1 1 0 1 1 1 0 YycC-like protein HTH_24 PF13412.6 ABX12773.1 - 0.084 12.5 0.2 0.084 12.5 0.2 1.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding CbtA PF09490.10 ABX12774.1 - 5.9e-53 180.1 0.8 6.6e-53 180.0 0.8 1.0 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) INSIG PF07281.12 ABX12774.1 - 0.011 15.5 0.1 3.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) Romo1 PF10247.9 ABX12774.1 - 0.084 13.3 2.9 0.12 12.7 0.1 2.6 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 5TM-5TMR_LYT PF07694.12 ABX12774.1 - 2.7 7.5 13.8 0.54 9.8 4.7 3.0 3 0 0 3 3 3 0 5TMR of 5TMR-LYT MFS_1 PF07690.16 ABX12774.1 - 5.8 5.7 17.0 3.2 6.6 13.5 2.3 2 1 0 2 2 2 0 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 ABX12774.1 - 7.3 6.1 5.6 5.7 6.5 1.1 3.0 2 1 0 2 2 2 0 ATP1G1/PLM/MAT8 family CbtB PF09489.10 ABX12775.1 - 4.1e-13 49.2 1.1 5.8e-13 48.7 1.1 1.3 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) DUF4443 PF14544.6 ABX12776.1 - 0.00017 21.7 0.0 0.00027 21.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4443) HTH_45 PF14947.6 ABX12776.1 - 0.0011 18.9 0.3 0.0025 17.8 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix RE_BsaWI PF18643.1 ABX12776.1 - 0.079 12.9 2.6 5.3 7.0 0.4 2.4 1 1 1 2 2 2 0 BsaWI restriction endonuclease type 2 Thioredoxin_4 PF13462.6 ABX12777.1 - 5.6e-31 107.9 0.0 7e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ABX12777.1 - 1.3e-13 51.1 0.0 2.4e-12 47.0 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ABX12777.1 - 1.9e-08 34.7 0.1 3.8e-08 33.7 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 ABX12777.1 - 0.00013 21.7 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin eRF1_2 PF03464.15 ABX12778.1 - 6.3e-29 101.0 0.0 1.5e-28 99.7 0.0 1.7 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.15 ABX12778.1 - 4.2e-20 72.3 0.2 4.4e-19 69.0 0.0 2.2 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 ABX12778.1 - 2.7e-10 40.4 0.0 5.6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 ABX12778.1 - 1.1e-06 28.9 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 ABX12778.1 - 2.5e-05 24.6 0.0 4.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 SpoU_sub_bind PF08032.12 ABX12778.1 - 0.1 12.9 0.1 1.1 9.6 0.0 2.6 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding HIT PF01230.23 ABX12779.1 - 1.2e-23 83.7 0.2 1.5e-23 83.3 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ABX12779.1 - 4.6e-13 49.7 0.1 5.8e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3149 PF11346.8 ABX12780.1 - 0.12 12.0 0.4 0.21 11.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF2749 PF10907.8 ABX12780.1 - 0.14 12.4 0.2 0.45 10.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) zinc_ribbon_13 PF09855.9 ABX12781.1 - 0.029 14.5 1.7 0.054 13.7 1.7 1.5 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF2225 PF09986.9 ABX12781.1 - 0.037 13.8 1.6 0.07 12.8 1.6 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Lar_restr_allev PF14354.6 ABX12781.1 - 0.042 14.2 0.1 0.05 14.0 0.1 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar ILVD_EDD PF00920.21 ABX12782.1 - 3.2e-207 689.3 5.5 3.6e-207 689.1 5.5 1.0 1 0 0 1 1 1 1 Dehydratase family DUF483 PF04467.12 ABX12783.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF483) Helicase_C_2 PF13307.6 ABX12784.1 - 2.4e-21 76.6 0.0 8e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 ABX12784.1 - 2.4e-05 24.0 0.2 6.5e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 ABX12784.1 - 0.063 13.3 4.1 0.19 11.7 1.4 2.3 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit GIY-YIG PF01541.24 ABX12785.1 - 0.00043 20.5 0.2 0.00057 20.1 0.2 1.4 1 1 0 1 1 1 1 GIY-YIG catalytic domain RPW8 PF05659.11 ABX12785.1 - 0.12 12.1 0.1 0.2 11.4 0.0 1.4 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 MacB_PCD PF12704.7 ABX12786.1 - 0.097 13.0 0.4 0.1 12.9 0.4 1.2 1 1 0 1 1 1 0 MacB-like periplasmic core domain WDCP PF15390.6 ABX12788.1 - 0.031 12.7 1.3 0.033 12.6 1.3 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Streptin-Immun PF11083.8 ABX12788.1 - 0.21 12.0 5.2 12 6.4 4.0 2.9 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein zinc_ribbon_4 PF13717.6 ABX12790.1 - 0.015 15.2 1.4 0.021 14.7 0.3 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Col_cuticle_N PF01484.17 ABX12792.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Lipocalin PF00061.23 ABX12794.1 - 0.055 13.7 0.3 0.084 13.1 0.0 1.5 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family YdfZ PF14001.6 ABX12795.1 - 0.045 14.2 0.0 0.062 13.7 0.0 1.1 1 0 0 1 1 1 0 YdfZ protein DUF4956 PF16316.5 ABX12796.1 - 0.013 15.2 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) PcrB PF01884.17 ABX12796.1 - 0.018 14.5 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 PcrB family YjcQ PF09639.10 ABX12797.1 - 0.0069 16.6 1.2 0.0082 16.3 1.2 1.1 1 0 0 1 1 1 1 YjcQ protein Snf7 PF03357.21 ABX12797.1 - 0.012 15.2 0.5 0.014 15.0 0.5 1.1 1 0 0 1 1 1 0 Snf7 FaeA PF04703.12 ABX12797.1 - 0.014 15.7 0.2 0.019 15.3 0.2 1.1 1 0 0 1 1 1 0 FaeA-like protein RPA_C PF08784.11 ABX12797.1 - 0.016 15.8 0.0 0.017 15.8 0.0 1.1 1 0 0 1 1 1 0 Replication protein A C terminal DUF3895 PF13034.6 ABX12797.1 - 0.018 15.1 0.9 0.63 10.1 0.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3895) z-alpha PF02295.17 ABX12797.1 - 0.021 14.9 0.5 0.029 14.4 0.5 1.2 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain HTH_46 PF15977.5 ABX12797.1 - 0.058 13.4 0.2 0.19 11.7 0.2 1.8 1 1 0 1 1 1 0 Winged helix-turn-helix DNA binding DUF5457 PF17540.2 ABX12797.1 - 0.065 13.3 3.1 0.11 12.6 3.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5457) SHOCT PF09851.9 ABX12798.1 - 6.3e-05 22.6 5.3 6.3e-05 22.6 5.3 2.6 2 0 0 2 2 2 1 Short C-terminal domain Nif11 PF07862.11 ABX12798.1 - 0.0061 16.8 0.5 0.16 12.3 0.1 2.8 3 1 0 3 3 3 1 Nif11 domain ATP-synt_B PF00430.18 ABX12798.1 - 0.025 14.7 8.5 0.025 14.7 6.8 1.8 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4570 PF15134.6 ABX12798.1 - 0.39 10.8 8.9 0.37 10.8 7.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) PIN_8 PF18476.1 ABX12798.1 - 0.49 10.2 11.4 0.8 9.5 11.4 1.5 1 1 0 1 1 1 0 PIN like domain PCNP PF15473.6 ABX12798.1 - 0.66 10.7 8.9 0.99 10.1 8.9 1.3 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family ENT PF03735.14 ABX12798.1 - 2.3 8.3 11.6 0.85 9.7 2.3 2.8 2 1 1 3 3 3 0 ENT domain CLZ PF16526.5 ABX12799.1 - 0.016 15.5 0.3 0.072 13.5 0.1 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3069 PF11269.8 ABX12801.1 - 0.064 13.5 1.7 0.097 12.9 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) PDDEXK_1 PF12705.7 ABX12802.1 - 7.1e-09 35.9 1.4 2.3e-08 34.3 1.3 1.6 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF3799 PF12684.7 ABX12802.1 - 0.0093 15.7 3.9 0.0095 15.7 2.0 1.8 2 0 0 2 2 2 1 PDDEXK-like domain of unknown function (DUF3799) DUF2800 PF10926.8 ABX12802.1 - 0.022 14.0 2.0 0.13 11.5 0.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2800) CheZ PF04344.13 ABX12802.1 - 0.046 13.6 0.8 0.079 12.9 0.5 1.6 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ MscS_porin PF12795.7 ABX12804.1 - 0.0046 16.5 3.8 0.0057 16.2 3.8 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Rad50_zn_hook PF04423.14 ABX12804.1 - 0.019 14.8 4.1 2.4 8.0 0.1 2.6 2 1 0 2 2 2 0 Rad50 zinc hook motif HTH_AraC PF00165.23 ABX12804.1 - 0.039 14.0 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family KIP1 PF07765.12 ABX12804.1 - 0.29 11.3 3.8 0.47 10.6 2.1 1.9 1 1 1 2 2 2 0 KIP1-like protein DUF4337 PF14235.6 ABX12804.1 - 0.49 10.5 2.2 0.52 10.4 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Polo_box_3 PF18544.1 ABX12805.1 - 0.032 14.9 0.3 0.038 14.6 0.3 1.1 1 0 0 1 1 1 0 Polo box domain PhetRS_B1 PF18262.1 ABX12805.1 - 0.042 14.1 0.2 0.13 12.5 0.0 1.9 1 1 1 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain VPS53_C PF16854.5 ABX12805.1 - 0.045 13.6 1.2 0.06 13.2 1.2 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus Pyrophosphatase PF00719.19 ABX12805.1 - 0.07 12.9 0.1 0.1 12.4 0.1 1.4 1 1 0 1 1 1 0 Inorganic pyrophosphatase FKS1_dom1 PF14288.6 ABX12806.1 - 0.59 10.5 5.3 0.85 10.0 2.9 2.2 1 1 1 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Chorismate_bind PF00425.18 ABX12807.1 - 2.8e-93 312.2 0.0 8e-93 310.7 0.0 1.7 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 ABX12807.1 - 1.2e-21 77.4 1.0 3.6e-18 66.1 0.1 2.9 2 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region FlbD PF06289.11 ABX12807.1 - 0.079 12.6 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins DSS1_SEM1 PF05160.13 ABX12807.1 - 1 9.4 6.5 0.91 9.6 1.7 2.5 2 0 0 2 2 2 0 DSS1/SEM1 family GATase PF00117.28 ABX12808.1 - 1e-53 182.0 0.1 1.1e-53 181.8 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ABX12808.1 - 9e-11 41.9 0.1 2.3e-10 40.6 0.1 1.6 1 1 0 1 1 1 1 Peptidase C26 Response_reg PF00072.24 ABX12808.1 - 0.081 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Response regulator receiver domain DJ-1_PfpI PF01965.24 ABX12808.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Glycos_transf_3 PF00591.21 ABX12809.1 - 3e-77 259.6 0.8 3e-77 259.6 0.8 1.4 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 ABX12809.1 - 1.1e-11 44.4 0.3 2.6e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Sigma70_r1_1 PF03979.14 ABX12809.1 - 0.22 11.6 2.5 0.29 11.2 0.8 2.2 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 IGPS PF00218.21 ABX12810.1 - 4.4e-70 235.7 0.8 5.3e-70 235.5 0.8 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.19 ABX12810.1 - 1.7e-05 24.7 0.0 4e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 ABX12810.1 - 0.00019 20.7 0.5 0.00049 19.3 0.2 1.8 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 ABX12810.1 - 0.0016 17.5 0.0 0.024 13.6 0.0 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Cellulase PF00150.18 ABX12810.1 - 0.021 14.3 0.1 0.042 13.3 0.1 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) His_biosynth PF00977.21 ABX12810.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 ABX12810.1 - 0.039 13.2 0.6 3.6 6.7 0.0 2.3 2 1 0 2 2 2 0 Dihydroorotate dehydrogenase AP_endonuc_2 PF01261.24 ABX12810.1 - 0.052 13.0 0.1 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel ThiG PF05690.14 ABX12810.1 - 0.12 11.6 0.1 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PALP PF00291.25 ABX12811.1 - 7.4e-45 153.6 0.9 9.4e-45 153.3 0.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Succ_CoA_lig PF13607.6 ABX12811.1 - 0.16 11.8 1.6 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Trp_syntA PF00290.20 ABX12812.1 - 3.3e-83 278.5 0.6 3.8e-83 278.3 0.6 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 ABX12812.1 - 1.1e-07 31.6 0.2 4e-07 29.7 0.1 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.21 ABX12812.1 - 3.2e-06 26.6 1.9 4.6e-06 26.1 1.9 1.3 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 ABX12812.1 - 2.4e-05 23.5 0.4 0.00024 20.2 0.1 2.3 1 1 1 3 3 3 1 FMN-dependent dehydrogenase BtpA PF03437.15 ABX12812.1 - 0.0001 21.9 1.1 0.0043 16.5 0.9 2.2 1 1 1 2 2 2 1 BtpA family PcrB PF01884.17 ABX12812.1 - 0.00021 20.8 0.6 0.00088 18.8 0.2 2.1 2 0 0 2 2 2 1 PcrB family IGPS PF00218.21 ABX12812.1 - 0.0014 17.9 0.0 0.066 12.4 0.0 2.3 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase ThiG PF05690.14 ABX12812.1 - 0.0016 17.8 0.1 0.0053 16.1 0.1 1.7 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 ABX12812.1 - 0.0026 16.8 1.2 0.0077 15.3 0.8 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 ABX12812.1 - 0.0044 16.4 0.9 0.015 14.6 0.7 2.1 3 1 0 3 3 3 1 Thiamine monophosphate synthase NanE PF04131.14 ABX12812.1 - 0.0069 15.6 0.2 0.034 13.3 0.1 2.2 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 ABX12812.1 - 0.015 14.7 0.0 0.029 13.8 0.0 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase PEP_mutase PF13714.6 ABX12812.1 - 0.019 14.4 0.0 13 5.2 0.0 2.8 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase DUF2482 PF10655.9 ABX12812.1 - 0.039 14.5 0.6 12 6.4 0.0 2.5 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) DUF720 PF05302.11 ABX12812.1 - 0.12 12.2 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF720) MSP7_C PF12948.7 ABX12813.1 - 0.024 15.3 0.4 0.024 15.3 0.4 2.6 1 1 0 2 2 2 0 MSP7-like protein C-terminal domain Copper-bind PF00127.20 ABX12814.1 - 0.0005 20.5 0.0 0.0014 19.0 0.0 1.7 2 0 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family CTP_synth_N PF06418.14 ABX12815.1 - 2.3e-116 387.7 0.2 3.3e-116 387.2 0.2 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 ABX12815.1 - 2.2e-54 184.1 0.0 3.9e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ABX12815.1 - 1.9e-11 44.1 0.0 9.1e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 ABX12815.1 - 0.0075 16.3 0.0 0.029 14.4 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DJ-1_PfpI PF01965.24 ABX12815.1 - 0.031 14.1 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family HATPase_c PF02518.26 ABX12816.1 - 7.7e-28 97.3 0.2 1.3e-27 96.5 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABX12816.1 - 2e-12 46.9 0.2 4.3e-12 45.9 0.2 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PorA PF11271.8 ABX12816.1 - 2.8e-10 40.0 1.2 4.8e-10 39.2 1.2 1.3 1 0 0 1 1 1 1 Porin PorA HATPase_c_3 PF13589.6 ABX12816.1 - 6.6e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 ABX12816.1 - 0.0051 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 GHKL domain DUF1397 PF07165.11 ABX12816.1 - 0.1 12.0 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) DUF1216 PF06746.11 ABX12816.1 - 0.57 10.2 2.3 18 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) NAD_kinase PF01513.21 ABX12817.1 - 4.3e-31 108.2 0.2 7.6e-31 107.4 0.2 1.3 1 0 0 1 1 1 1 ATP-NAD kinase HTH_24 PF13412.6 ABX12817.1 - 4.4e-05 22.9 0.5 0.00021 20.8 0.0 2.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABX12817.1 - 4.9e-05 23.1 1.7 0.005 16.7 0.3 2.7 2 1 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 ABX12817.1 - 0.00013 21.8 0.6 0.00034 20.5 0.1 1.9 2 0 0 2 2 2 1 MarR family RNA_pol_Rpc34 PF05158.12 ABX12817.1 - 0.0014 18.1 0.5 0.0021 17.5 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR_2 PF12802.7 ABX12817.1 - 0.0021 17.9 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 MarR family TPALS PF18178.1 ABX12817.1 - 0.008 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 TIR- and PNP-associating SLOG family HTH_27 PF13463.6 ABX12817.1 - 0.018 15.5 0.1 0.038 14.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain PfkB PF00294.24 ABX12818.1 - 8.9e-12 44.9 0.2 3.4e-11 43.0 0.2 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Macscav_rec PF03523.13 ABX12818.1 - 0.014 15.2 0.9 0.024 14.5 0.1 1.7 2 0 0 2 2 2 0 Macrophage scavenger receptor Phos_pyr_kin PF08543.12 ABX12818.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase S1_2 PF13509.6 ABX12818.1 - 0.06 13.4 0.6 4.4 7.4 0.1 2.9 2 1 1 3 3 3 0 S1 domain Amidinotransf PF02274.17 ABX12818.1 - 0.081 12.0 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase Ribosomal_S26e PF01283.19 ABX12819.1 - 4.3e-24 85.0 0.8 5.2e-24 84.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e CxC5 PF18718.1 ABX12819.1 - 0.017 15.2 0.3 0.02 15.0 0.3 1.1 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases zf-dskA_traR PF01258.17 ABX12819.1 - 0.033 14.1 0.1 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger ADD_ATRX PF17981.1 ABX12819.1 - 0.053 13.4 0.2 0.053 13.4 0.2 1.6 2 0 0 2 2 2 0 Cysteine Rich ADD domain zinc_ribbon_4 PF13717.6 ABX12819.1 - 0.18 11.8 2.0 0.65 10.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain CDP-OH_P_transf PF01066.21 ABX12820.1 - 1.1e-10 42.2 0.4 1.1e-10 42.2 0.4 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ECSCR PF15820.5 ABX12820.1 - 0.74 9.7 4.9 1.9 8.3 4.9 1.7 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Arginase PF00491.21 ABX12821.1 - 3.2e-66 223.7 0.1 4.2e-66 223.3 0.1 1.0 1 0 0 1 1 1 1 Arginase family tRNA-Thr_ED PF08915.11 ABX12822.1 - 1.6e-43 148.1 0.3 2.9e-43 147.2 0.3 1.5 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase HGTP_anticodon PF03129.20 ABX12822.1 - 1.4e-24 86.1 0.4 2.8e-24 85.1 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ABX12822.1 - 7.7e-17 61.8 0.1 1.7e-16 60.7 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1896 PF08989.10 ABX12823.1 - 0.036 14.2 0.0 0.046 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) DS PF01916.17 ABX12824.1 - 8.7e-78 261.5 0.1 1e-77 261.3 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase FmdE PF02663.14 ABX12825.1 - 0.075 13.1 0.1 0.091 12.8 0.1 1.1 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Ribosomal_S25 PF03297.15 ABX12826.1 - 1.2e-08 35.1 4.6 1.5e-08 34.7 4.6 1.1 1 0 0 1 1 1 1 S25 ribosomal protein TrmB PF01978.19 ABX12826.1 - 0.0037 17.1 0.1 0.0048 16.8 0.1 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 ABX12826.1 - 0.0043 16.6 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF977 PF06163.11 ABX12826.1 - 0.023 14.6 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) MarR_2 PF12802.7 ABX12826.1 - 0.033 14.1 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 MarR family MarR PF01047.22 ABX12826.1 - 0.055 13.4 0.1 0.086 12.8 0.1 1.3 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 ABX12826.1 - 0.067 13.2 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Cyclophil_like PF04126.13 ABX12827.1 - 2.1e-08 34.0 0.0 2.5e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 ABX12827.1 - 3.8e-06 26.8 0.0 4.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin-like family RNA_pol_Rpb6 PF01192.22 ABX12828.1 - 6.2e-10 38.9 0.0 6.2e-10 38.9 0.0 2.6 3 1 0 3 3 3 1 RNA polymerase Rpb6 Cauli_AT PF03233.13 ABX12828.1 - 0.49 10.3 3.9 0.7 9.8 3.9 1.2 1 0 0 1 1 1 0 Aphid transmission protein Alba PF01918.21 ABX12829.1 - 6.1e-13 48.4 0.8 8.1e-13 48.0 0.8 1.2 1 0 0 1 1 1 1 Alba RNase_HII PF01351.18 ABX12829.1 - 0.011 15.6 0.2 0.012 15.5 0.2 1.1 1 0 0 1 1 1 0 Ribonuclease HII HTH_3 PF01381.22 ABX12830.1 - 4.7e-05 23.4 0.0 0.00013 21.9 0.0 1.9 1 1 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.6 ABX12830.1 - 0.0072 16.1 0.0 0.014 15.1 0.0 1.5 1 1 0 1 1 1 1 Homeodomain-like domain DUF483 PF04467.12 ABX12830.1 - 0.053 13.5 0.1 0.16 12.0 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF483) HTH_11 PF08279.12 ABX12830.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_19 PF12844.7 ABX12830.1 - 0.11 12.6 0.1 0.55 10.3 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 ABX12830.1 - 0.12 12.2 0.0 0.61 10.0 0.0 2.1 1 1 1 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Asn_synthase PF00733.21 ABX12831.1 - 2.2e-36 126.3 0.0 1.9e-20 73.8 0.0 2.0 1 1 0 2 2 2 2 Asparagine synthase QueC PF06508.13 ABX12831.1 - 0.00041 19.9 0.1 0.0023 17.4 0.1 2.2 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 ABX12831.1 - 0.0011 18.1 0.2 0.0022 17.2 0.0 1.5 2 0 0 2 2 2 1 NAD synthase DZR PF12773.7 ABX12831.1 - 0.0023 17.9 1.8 0.016 15.2 0.5 2.2 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 ABX12831.1 - 0.011 15.5 3.2 0.83 9.4 4.2 2.6 1 1 1 2 2 2 0 zinc-ribbon domain tRNA_Me_trans PF03054.16 ABX12831.1 - 0.015 14.1 0.0 0.03 13.1 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase zinc_ribbon_15 PF17032.5 ABX12831.1 - 0.039 14.7 1.8 0.16 12.7 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon family Cript PF10235.9 ABX12831.1 - 0.069 13.7 3.7 0.75 10.4 0.9 2.5 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT UPF0547 PF10571.9 ABX12831.1 - 0.072 13.2 1.8 0.21 11.7 1.8 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 ATP_bind_3 PF01171.20 ABX12831.1 - 0.073 12.8 0.0 0.2 11.4 0.0 1.7 1 1 0 1 1 1 0 PP-loop family zf-ribbon_3 PF13248.6 ABX12831.1 - 0.12 11.9 7.1 0.22 11.0 1.9 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Aldo_ket_red PF00248.21 ABX12833.1 - 9.1e-25 87.4 0.0 3.7e-18 65.7 0.0 2.3 1 1 1 2 2 2 2 Aldo/keto reductase family ATPgrasp_Ter PF15632.6 ABX12833.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF321 PF03778.13 ABX12833.1 - 0.16 11.7 0.3 0.33 10.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF321) YdiH PF15930.5 ABX12833.1 - 0.18 12.0 0.0 5.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function UbiA PF01040.18 ABX12834.1 - 3e-28 98.8 13.9 4.1e-28 98.4 13.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family TMEM43 PF07787.12 ABX12834.1 - 0.73 9.2 2.2 2.2 7.6 2.2 1.8 1 0 0 1 1 1 0 Transmembrane protein 43 DUF2203 PF09969.9 ABX12835.1 - 1.2e-36 126.1 0.1 1.4e-36 125.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) GCR1_C PF12550.8 ABX12835.1 - 0.0098 16.2 0.2 0.0098 16.2 0.2 1.8 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes rRNA_proc-arch PF13234.6 ABX12835.1 - 0.016 15.1 1.8 0.021 14.8 1.8 1.1 1 0 0 1 1 1 0 rRNA-processing arch domain Peptidase_M57 PF12388.8 ABX12835.1 - 0.13 11.8 0.6 0.16 11.6 0.6 1.1 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Putative_PNPOx PF01243.20 ABX12837.1 - 2.9e-11 43.4 0.0 3.6e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 ABX12837.1 - 2.3e-07 30.9 0.0 2.7e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.12 ABX12837.1 - 0.038 13.8 0.2 0.055 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Rotamase_3 PF13616.6 ABX12838.1 - 1.7e-25 89.9 0.5 2.6e-25 89.2 0.5 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 ABX12838.1 - 3.8e-24 85.5 0.1 4.7e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 ABX12838.1 - 4.6e-10 40.4 0.0 5.6e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain NTPase_I-T PF01931.18 ABX12838.1 - 0.0061 16.4 0.0 0.0085 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF84 Cyclophil_like2 PF18050.1 ABX12838.1 - 0.098 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Cyclophilin-like family Helicase_C PF00271.31 ABX12840.1 - 7.8e-23 80.9 0.1 2.1e-22 79.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ABX12840.1 - 7.9e-20 71.3 0.0 2e-19 70.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 ABX12840.1 - 5.1e-19 68.9 0.0 1.1e-18 67.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 ABX12840.1 - 0.00021 21.3 0.0 0.0005 20.1 0.0 1.6 1 1 0 1 1 1 1 Flavivirus DEAD domain DUF4862 PF16154.5 ABX12840.1 - 0.067 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4862) BDV_P24 PF06595.11 ABX12841.1 - 0.078 12.9 0.0 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 Borna disease virus P24 protein APG5 PF04106.12 ABX12842.1 - 0.25 10.9 2.8 0.25 10.9 2.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg5 dCMP_cyt_deam_1 PF00383.23 ABX12843.1 - 8.7e-27 93.0 1.0 1.2e-26 92.6 1.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ABX12843.1 - 5.7e-14 52.0 0.2 7.3e-14 51.7 0.2 1.1 1 0 0 1 1 1 1 MafB19-like deaminase DNA_pol_B PF00136.21 ABX12844.1 - 1.6e-56 192.0 5.1 2.6e-56 191.2 5.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ABX12844.1 - 1.1e-39 136.5 4.5 2.2e-39 135.6 4.5 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.6 ABX12844.1 - 1.4e-06 28.4 1.8 4.1e-06 26.9 1.8 1.8 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 ABX12844.1 - 3.7e-06 26.8 1.3 9.7e-06 25.4 1.3 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB MtN3_slv PF03083.16 ABX12845.1 - 3.3e-09 36.6 3.1 3.9e-09 36.4 3.1 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 ABX12845.1 - 0.00019 21.1 2.1 0.00034 20.3 2.1 1.5 1 0 0 1 1 1 1 PQ loop repeat LAB_N PF07578.11 ABX12845.1 - 0.046 13.8 1.4 0.061 13.4 1.4 1.2 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain DUF3487 PF11990.8 ABX12845.1 - 0.58 10.0 3.5 0.39 10.6 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF3784 PF12650.7 ABX12845.1 - 0.88 9.8 12.7 5.4 7.3 12.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) TIM PF00121.18 ABX12846.1 - 1.7e-11 43.9 4.4 2.1e-11 43.7 1.1 2.0 1 1 1 2 2 2 1 Triosephosphate isomerase ThiG PF05690.14 ABX12846.1 - 0.00039 19.8 0.1 0.00054 19.3 0.1 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IGPS PF00218.21 ABX12846.1 - 0.00072 18.8 0.1 0.0014 17.8 0.1 1.4 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.18 ABX12846.1 - 0.0025 16.9 0.2 0.0044 16.1 0.1 1.4 2 0 0 2 2 2 1 FMN-dependent dehydrogenase ArgoMid PF16487.5 ABX12846.1 - 0.032 14.5 0.3 8.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Mid domain of argonaute Zea_mays_MuDR PF05928.11 ABX12846.1 - 0.069 12.8 0.3 2.3 7.8 0.0 2.2 1 1 0 2 2 2 0 Zea mays MURB-like protein (MuDR) PEP-utilizers_C PF02896.18 ABX12847.1 - 2.4e-84 282.9 0.7 4.3e-84 282.1 0.7 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 ABX12847.1 - 3.4e-57 194.2 0.9 3.5e-34 118.6 0.0 3.6 2 1 2 4 4 4 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 ABX12847.1 - 6e-22 77.2 0.1 1.5e-21 75.8 0.1 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HTH_3 PF01381.22 ABX12848.1 - 2.7e-15 56.1 0.4 4.8e-15 55.4 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix CBS PF00571.28 ABX12848.1 - 4.1e-13 49.6 0.2 1.6e-09 38.1 0.0 2.3 2 0 0 2 2 2 2 CBS domain HTH_19 PF12844.7 ABX12848.1 - 7.1e-11 42.0 0.7 1.5e-10 41.0 0.4 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 ABX12848.1 - 3.3e-07 30.6 0.0 5.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 ABX12848.1 - 0.0005 20.2 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_25 PF13413.6 ABX12848.1 - 0.0007 19.4 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 ABX12848.1 - 0.0077 16.2 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 ABX12848.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF4447 PF14590.6 ABX12848.1 - 0.088 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) Sigma70_r4 PF04545.16 ABX12848.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_26 PF13443.6 ABX12848.1 - 0.12 12.9 0.2 0.22 12.0 0.2 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_Crp_2 PF13545.6 ABX12848.1 - 0.17 11.8 0.1 0.4 10.7 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Glyoxalase_4 PF13669.6 ABX12849.1 - 3e-23 82.2 0.1 3.5e-23 81.9 0.1 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 ABX12849.1 - 4.4e-13 49.5 0.0 4.7e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ABX12849.1 - 1.3e-10 41.7 0.0 1.5e-10 41.5 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ABX12849.1 - 0.00011 22.9 0.0 0.00014 22.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain MM_CoA_mutase PF01642.22 ABX12850.1 - 2.6e-214 712.5 0.2 3e-214 712.4 0.2 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase HigB_toxin PF09907.9 ABX12850.1 - 0.21 11.8 1.5 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system MeaB PF03308.16 ABX12851.1 - 7.7e-72 241.5 4.7 9.3e-72 241.2 4.7 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 ABX12851.1 - 2.8e-06 27.1 0.1 2.8e-06 27.1 0.1 2.3 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 ABX12851.1 - 3.9e-06 26.8 0.4 0.0049 16.7 0.3 2.5 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 ABX12851.1 - 3.2e-05 23.9 1.3 0.0013 18.7 0.2 2.6 2 1 0 2 2 2 1 RsgA GTPase KAP_NTPase PF07693.14 ABX12851.1 - 8.3e-05 22.0 6.2 0.00018 20.9 4.4 2.2 1 1 1 2 2 2 1 KAP family P-loop domain AAA_30 PF13604.6 ABX12851.1 - 0.0037 17.0 0.8 0.0074 16.0 0.8 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ABX12851.1 - 0.0045 16.7 2.1 0.2 11.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ABX12851.1 - 0.0069 16.9 10.5 0.084 13.4 1.0 2.6 2 1 0 2 2 2 2 AAA domain Ubiq_cyt_C_chap PF03981.12 ABX12851.1 - 0.0074 16.4 0.7 0.015 15.4 0.7 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone MnmE_helical PF12631.7 ABX12851.1 - 0.0084 16.3 0.1 0.014 15.6 0.1 1.4 1 1 0 1 1 1 1 MnmE helical domain AAA_16 PF13191.6 ABX12851.1 - 0.011 16.1 0.2 0.03 14.7 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 ABX12851.1 - 0.014 14.6 0.3 0.014 14.6 0.3 1.8 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 ABX12851.1 - 0.017 15.6 1.0 0.062 13.8 0.1 2.3 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 ABX12851.1 - 0.017 15.0 1.6 0.072 13.0 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 ABX12851.1 - 0.018 15.0 0.4 0.06 13.3 0.1 2.1 2 0 0 2 2 2 0 NTPase Spore_IV_A PF09547.10 ABX12851.1 - 0.024 13.6 0.1 0.024 13.6 0.1 2.1 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) Flagellin_N PF00669.20 ABX12851.1 - 0.038 14.1 5.2 3.8 7.6 0.1 3.2 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region AAA_22 PF13401.6 ABX12851.1 - 0.04 14.2 0.8 0.53 10.6 0.1 2.6 2 1 1 3 3 3 0 AAA domain PRK PF00485.18 ABX12851.1 - 0.042 13.6 1.4 0.082 12.6 0.2 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 ABX12851.1 - 0.047 13.8 4.0 0.042 13.9 0.7 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase PhoH PF02562.16 ABX12851.1 - 0.049 13.1 2.3 0.058 12.8 0.2 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 ABX12851.1 - 0.057 13.7 7.0 1.5 9.1 7.0 2.4 1 1 0 1 1 1 0 AAA domain DUF4375 PF14300.6 ABX12851.1 - 0.066 13.5 0.6 0.21 11.9 0.5 1.9 3 0 0 3 3 1 0 Domain of unknown function (DUF4375) AAA_29 PF13555.6 ABX12851.1 - 0.089 12.5 0.5 0.2 11.4 0.5 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_pol_Rpb1_3 PF04983.18 ABX12851.1 - 0.11 12.4 1.8 0.15 12.0 0.4 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 3 AAA_18 PF13238.6 ABX12851.1 - 0.12 12.9 0.9 0.49 10.9 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_35 PF14516.6 ABX12851.1 - 0.13 11.1 1.1 0.16 10.8 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain Peptidase_M1 PF01433.20 ABX12853.1 - 3.6e-89 298.1 0.6 7.3e-89 297.0 0.6 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 ABX12853.1 - 1.3e-65 222.0 0.0 9.3e-65 219.2 0.0 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 ABX12853.1 - 1.6e-52 178.4 0.8 3.3e-52 177.4 0.8 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 ABX12853.1 - 0.015 14.6 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Putative aminopeptidase YmgD PF16456.5 ABX12853.1 - 0.092 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 YmgD protein B12-binding PF02310.19 ABX12854.1 - 4.2e-23 81.7 0.3 4.7e-23 81.5 0.3 1.0 1 0 0 1 1 1 1 B12 binding domain IMPDH PF00478.25 ABX12854.1 - 0.00022 20.3 0.1 0.00026 20.1 0.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 ABX12854.1 - 0.084 12.3 0.4 0.75 9.2 0.2 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein Peptidase_M22 PF00814.25 ABX12854.1 - 0.088 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycoprotease family IlvN PF07991.12 ABX12855.1 - 9.6e-67 223.7 0.5 1.3e-66 223.2 0.5 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ABX12855.1 - 6.6e-56 188.6 2.2 1e-55 188.0 2.2 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 ABX12855.1 - 2.4e-06 27.0 0.1 4.2e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ABX12855.1 - 0.00021 21.5 0.4 0.0015 18.7 0.1 2.3 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ABX12855.1 - 0.00078 20.0 0.2 0.0017 18.9 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 ABX12855.1 - 0.0053 16.8 0.2 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF4085 PF13315.6 ABX12855.1 - 0.097 12.3 0.8 0.17 11.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) DUF4897 PF16238.5 ABX12855.1 - 0.1 12.4 0.9 0.25 11.2 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4897) CTP_transf_like PF01467.26 ABX12856.1 - 1.4e-13 51.2 0.1 2.3e-13 50.6 0.1 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 ABX12856.1 - 7.4e-05 22.1 0.1 0.035 13.3 0.0 2.1 2 0 0 2 2 2 2 HIGH Nucleotidyl Transferase Citrate_ly_lig PF08218.11 ABX12856.1 - 0.00026 20.7 0.2 0.0071 16.0 0.1 2.1 1 1 1 2 2 2 1 Citrate lyase ligase C-terminal domain FAD_syn PF06574.12 ABX12856.1 - 0.049 13.5 0.0 0.074 12.9 0.0 1.4 1 1 0 1 1 1 0 FAD synthetase Pantoate_ligase PF02569.15 ABX12856.1 - 0.068 12.4 0.1 0.14 11.3 0.0 1.5 1 1 0 1 1 1 0 Pantoate-beta-alanine ligase GTP_EFTU_D2 PF03144.25 ABX12857.1 - 2.8e-08 34.0 0.2 6.7e-08 32.8 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF726 PF05277.12 ABX12858.1 - 2.1e-10 40.1 0.0 3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.12 ABX12858.1 - 1.6e-09 37.7 0.1 2.2e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 ABX12858.1 - 2.5e-05 23.9 1.1 0.00031 20.3 1.1 2.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 ABX12858.1 - 0.00011 22.1 0.1 0.00015 21.6 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) LIDHydrolase PF10230.9 ABX12858.1 - 0.00082 19.0 0.1 0.001 18.7 0.1 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 ABX12858.1 - 0.00098 18.5 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 ABX12858.1 - 0.0012 18.9 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Cutinase LCAT PF02450.15 ABX12858.1 - 0.0033 16.6 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 ABX12858.1 - 0.0043 16.2 0.0 0.0062 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_8 PF06259.12 ABX12858.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase VirJ PF06057.11 ABX12858.1 - 0.091 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) tRNA-synt_1g PF09334.11 ABX12859.1 - 7.5e-139 462.8 1.8 1.1e-138 462.3 1.8 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ABX12859.1 - 1.1e-17 63.5 1.1 2.1e-07 29.6 0.2 4.1 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 ABX12859.1 - 7e-13 48.6 0.6 1.8e-06 27.6 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 ABX12859.1 - 2.2e-07 31.0 0.0 4.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 ABX12859.1 - 1.1e-06 27.9 0.1 0.0012 17.9 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class I (K) FhuF PF06276.12 ABX12859.1 - 0.0075 16.7 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter zf-Di19 PF05605.12 ABX12859.1 - 0.11 12.8 3.6 0.25 11.6 3.6 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 ABX12859.1 - 1.7 8.7 7.8 2.6 8.2 6.9 1.7 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 ABX12859.1 - 4.5 6.9 6.5 2.1 7.9 3.8 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding AdoHcyase PF05221.17 ABX12860.1 - 4.1e-52 177.2 0.0 4.4e-25 88.4 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 ABX12860.1 - 1.2e-51 175.0 1.2 1.2e-51 175.0 1.2 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 ABX12860.1 - 9.7e-10 38.1 0.7 3.6e-09 36.2 0.2 2.1 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ABX12860.1 - 1.4e-06 28.0 0.3 3.3e-06 26.8 0.1 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 ABX12860.1 - 0.00056 20.1 0.0 0.0048 17.2 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.20 ABX12860.1 - 0.0011 19.0 1.9 0.09 12.8 0.1 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DUF364 PF04016.12 ABX12860.1 - 0.026 14.1 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 Putative heavy-metal chelation 3HCDH_N PF02737.18 ABX12860.1 - 0.033 14.1 0.3 0.033 14.1 0.3 2.5 3 1 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ABX12860.1 - 0.033 13.5 3.5 0.2 10.9 3.5 2.3 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.19 ABX12860.1 - 0.036 13.4 0.7 0.45 9.8 0.6 2.7 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox_2 PF07992.14 ABX12860.1 - 0.037 13.2 1.6 0.13 11.5 0.1 2.3 1 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 ABX12860.1 - 0.055 13.0 0.2 0.14 11.7 0.2 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rieske PF00355.26 ABX12861.1 - 1.7e-14 53.5 0.0 1.9e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ABX12861.1 - 4.2e-13 49.1 0.0 4.9e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_synthase PF02540.17 ABX12862.1 - 4.1e-71 238.9 0.2 4.7e-71 238.7 0.2 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 ABX12862.1 - 0.001 17.9 0.0 0.024 13.4 0.0 2.3 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 ABX12862.1 - 0.0061 16.1 0.0 0.035 13.6 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 ABX12862.1 - 0.033 14.0 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 PP-loop family ThiI PF02568.14 ABX12862.1 - 0.097 12.2 0.0 0.6 9.7 0.0 2.0 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 ABX12862.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase HTH_23 PF13384.6 ABX12862.1 - 0.15 11.9 0.0 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_25 PF13413.6 ABX12862.1 - 0.16 11.9 0.2 6.7 6.6 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain tRNA-synt_1e PF01406.19 ABX12863.1 - 4.1e-126 420.4 1.1 4.1e-126 420.4 1.1 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ABX12863.1 - 3.3e-12 45.9 1.6 1.9e-07 30.2 1.2 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 ABX12863.1 - 5.2e-10 39.7 0.8 5.2e-10 39.7 0.8 2.2 3 0 0 3 3 3 1 DALR domain tRNA-synt_1 PF00133.22 ABX12863.1 - 2.9e-08 32.5 0.0 2.2e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 ABX12863.1 - 7.6e-08 31.7 0.1 0.0015 17.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Adenylsucc_synt PF00709.21 ABX12863.1 - 0.048 12.6 0.1 0.11 11.4 0.1 1.5 1 0 0 1 1 1 0 Adenylosuccinate synthetase DNA_pol3_a_NII PF11490.8 ABX12863.1 - 0.067 13.1 0.4 0.067 13.1 0.4 3.3 4 0 0 4 4 4 0 DNA polymerase III polC-type N-terminus II tRNA-synt_1c PF00749.21 ABX12863.1 - 0.96 8.3 8.9 0.58 9.0 2.4 3.3 3 1 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain Citrus_P18 PF05520.11 ABX12864.1 - 0.024 14.3 0.2 0.028 14.2 0.2 1.1 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein Pyr_excise PF03013.14 ABX12865.1 - 2.2e-13 50.3 0.3 3.6e-13 49.6 0.3 1.4 1 1 0 1 1 1 1 Pyrimidine dimer DNA glycosylase Insulin_TMD PF17870.1 ABX12866.1 - 0.028 14.5 2.6 0.15 12.1 0.1 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment MS_channel PF00924.18 ABX12867.1 - 1e-47 162.3 1.1 1.4e-47 161.9 1.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel MFS_1 PF07690.16 ABX12867.1 - 0.72 8.7 10.8 0.99 8.3 10.8 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Tetraspanin PF00335.20 ABX12867.1 - 2 8.1 6.2 3.1 7.4 6.2 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF432 PF04254.13 ABX12868.1 - 3e-33 114.6 0.0 4.6e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF432) DUF1722 PF08349.11 ABX12870.1 - 1.3e-33 115.7 3.2 1.3e-33 115.7 3.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1722) FokI_N PF02981.15 ABX12870.1 - 0.048 13.8 0.6 3.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease FokI, recognition domain Nre_N PF04894.12 ABX12871.1 - 2e-92 309.9 0.0 2.8e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 Archaeal Nre, N-terminal Nre_C PF04895.12 ABX12871.1 - 1.3e-33 115.2 0.0 2e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal Nre, C-terminal Toxin_trans PF07952.12 ABX12871.1 - 0.0071 15.5 0.1 0.025 13.7 0.1 1.9 1 1 0 1 1 1 1 Clostridium neurotoxin, Translocation domain Peripla_BP_2 PF01497.18 ABX12872.1 - 1.2e-22 80.7 0.2 1.7e-22 80.1 0.2 1.2 1 0 0 1 1 1 1 Periplasmic binding protein HGD-D PF06050.13 ABX12872.1 - 0.018 14.8 0.2 0.022 14.5 0.2 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Nro1 PF12753.7 ABX12872.1 - 0.019 14.0 0.3 0.037 13.0 0.2 1.4 1 1 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF5398 PF17376.2 ABX12872.1 - 0.06 14.0 1.6 0.14 12.8 1.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5398) NAD_binding_10 PF13460.6 ABX12873.1 - 1.9e-12 47.5 0.0 2.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ABX12873.1 - 2.8e-10 40.1 0.0 4.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ABX12873.1 - 5.1e-10 39.3 0.0 7.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 ABX12873.1 - 1.5e-07 30.7 0.0 2.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ABX12873.1 - 6.3e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ABX12873.1 - 0.0037 16.5 0.1 0.024 13.8 0.0 2.2 2 1 1 3 3 3 1 Male sterility protein RmlD_sub_bind PF04321.17 ABX12873.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain PAC2 PF09754.9 ABX12873.1 - 0.087 12.8 0.0 0.22 11.5 0.0 1.4 1 1 0 1 1 1 0 PAC2 family B12-binding PF02310.19 ABX12874.1 - 2.6e-11 43.6 0.0 4.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 ABX12874.1 - 5.3e-09 36.4 0.0 8.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain Mad3_BUB1_I PF08311.12 ABX12874.1 - 0.0066 16.4 0.5 0.014 15.4 0.5 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Response_reg PF00072.24 ABX12874.1 - 0.008 16.3 0.0 0.022 14.9 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain TFIIB PF00382.19 ABX12875.1 - 1.1e-29 102.3 2.4 4.4e-16 58.7 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ABX12875.1 - 2.4e-08 33.4 0.4 4.1e-08 32.6 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 ABX12875.1 - 9.5e-05 22.5 0.0 0.00042 20.4 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 ABX12875.1 - 0.00065 19.4 0.1 0.16 11.7 0.0 2.2 1 1 0 2 2 2 2 Cyclin, N-terminal domain RB_B PF01857.20 ABX12875.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain HTH_AsnC-type PF13404.6 ABX12875.1 - 0.017 14.9 0.0 1.4 8.8 0.0 3.3 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABX12875.1 - 0.018 14.6 0.1 0.15 11.7 0.1 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 ABX12875.1 - 0.083 13.3 0.2 34 4.9 0.0 3.4 3 1 1 4 4 4 0 Transcriptional regulator GerE PF00196.19 ABX12875.1 - 0.085 12.4 0.5 10 5.8 0.1 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 ABX12875.1 - 0.11 12.0 0.1 2.5 7.7 0.1 2.9 3 1 1 4 4 4 0 Sigma-70, region 4 MMR_HSR1_C PF08438.10 ABX12876.1 - 1.2e-31 109.6 0.0 2.7e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 ABX12876.1 - 5.1e-19 68.4 0.0 2.3e-18 66.4 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 ABX12876.1 - 2.8e-07 30.5 0.0 5.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 ABX12876.1 - 1.5e-05 24.6 0.0 0.00067 19.2 0.1 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ABX12876.1 - 0.00089 19.4 0.7 0.18 11.8 0.0 3.1 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 ABX12876.1 - 0.034 13.7 0.7 7 6.1 0.2 3.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Flagellin_N PF00669.20 ABX12877.1 - 0.068 13.3 0.1 0.13 12.4 0.1 1.6 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region Inhibitor_G39P PF11417.8 ABX12877.1 - 0.19 12.3 1.1 0.24 11.9 0.2 1.6 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P CoA_binding_2 PF13380.6 ABX12878.1 - 4.4e-41 140.0 0.1 5.1e-41 139.8 0.1 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 ABX12878.1 - 4e-09 37.0 0.0 8.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 CoA binding domain Glyco_hydro_57 PF03065.15 ABX12878.1 - 0.063 12.5 0.0 0.12 11.5 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 DUF4423 PF14394.6 ABX12879.1 - 2.5e-05 24.1 0.2 3.3e-05 23.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_34 PF13601.6 ABX12879.1 - 0.0011 19.1 0.2 0.0017 18.5 0.2 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 ABX12879.1 - 0.0018 18.1 0.1 0.0026 17.6 0.1 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 ABX12879.1 - 0.0037 17.1 0.6 0.0056 16.5 0.6 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit MarR_2 PF12802.7 ABX12879.1 - 0.0038 17.1 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_45 PF14947.6 ABX12879.1 - 0.01 15.8 0.1 0.019 15.0 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix MarR PF01047.22 ABX12879.1 - 0.062 13.2 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 MarR family APG17 PF04108.12 ABX12879.1 - 0.069 12.2 0.2 0.088 11.9 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF2250 PF10007.9 ABX12879.1 - 0.14 12.3 0.2 0.3 11.2 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Cdc6_C PF09079.11 ABX12879.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Rio2_N PF09202.11 ABX12879.1 - 0.16 12.2 0.1 0.34 11.2 0.1 1.5 1 0 0 1 1 1 0 Rio2, N-terminal BPL_LplA_LipB PF03099.19 ABX12880.1 - 2e-18 66.6 0.1 5.3e-18 65.2 0.0 1.7 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.12 ABX12880.1 - 5.6e-14 51.8 0.6 1.6e-13 50.4 0.1 2.1 2 0 0 2 2 2 1 HTH domain BPL_C PF02237.17 ABX12880.1 - 8.2e-07 28.8 1.5 1.5e-06 28.0 1.5 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain UPF0122 PF04297.14 ABX12880.1 - 0.0028 17.9 0.2 0.027 14.7 0.0 2.1 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like Rrf2 PF02082.20 ABX12880.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Glyco_transf_88 PF16849.5 ABX12881.1 - 0.023 13.6 0.5 0.028 13.3 0.5 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 88 AATF-Che1 PF13339.6 ABX12881.1 - 0.025 15.2 5.3 0.046 14.4 5.3 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor BAR_3 PF16746.5 ABX12881.1 - 0.033 13.9 3.2 0.036 13.8 3.2 1.0 1 0 0 1 1 1 0 BAR domain of APPL family Talin_middle PF09141.10 ABX12881.1 - 0.047 13.7 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 Talin, middle domain DUF948 PF06103.11 ABX12881.1 - 0.076 13.3 0.4 3.5 8.0 0.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.8 ABX12881.1 - 0.12 12.6 4.1 0.31 11.3 4.1 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 ABX12881.1 - 0.37 11.5 3.3 4.6 7.9 0.9 2.1 1 1 1 2 2 2 0 Initiation control protein YabA TPR_1 PF00515.28 ABX12882.1 - 1.9e-15 55.9 0.0 0.00042 20.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ABX12882.1 - 1.6e-13 49.6 0.0 0.00028 20.7 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat Peptidase_M10 PF00413.24 ABX12882.1 - 2.1e-08 34.2 0.2 5.7e-08 32.8 0.2 1.7 1 1 0 1 1 1 1 Matrixin TPR_8 PF13181.6 ABX12882.1 - 4.1e-08 32.8 0.4 0.025 14.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ABX12882.1 - 1.2e-07 31.9 0.0 0.0028 17.9 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Reprolysin_5 PF13688.6 ABX12882.1 - 1.9e-07 31.4 0.1 4.2e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 TPR_14 PF13428.6 ABX12882.1 - 5.1e-06 26.9 0.0 0.089 13.7 0.0 3.6 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ABX12882.1 - 6e-06 25.9 0.0 0.12 12.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ABX12882.1 - 6.3e-06 26.6 0.0 0.021 15.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 ABX12882.1 - 2.3e-05 24.7 0.1 0.42 11.4 0.0 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat Peptidase_M57 PF12388.8 ABX12882.1 - 2.6e-05 23.9 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Fis1_TPR_C PF14853.6 ABX12882.1 - 3.5e-05 23.8 0.0 0.79 9.8 0.0 3.4 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 ABX12882.1 - 0.00014 22.0 0.0 2.4 8.8 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 ABX12882.1 - 0.0012 18.7 0.1 0.53 10.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ABX12882.1 - 0.0017 18.9 0.0 1.4 9.7 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 ABX12882.1 - 0.0045 17.1 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Reprolysin_3 PF13582.6 ABX12882.1 - 0.0074 16.8 0.3 0.025 15.1 0.3 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like MIT PF04212.18 ABX12882.1 - 0.017 15.1 0.2 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Peptidase_M54 PF07998.11 ABX12882.1 - 0.02 14.9 0.2 0.048 13.6 0.1 1.8 2 0 0 2 2 2 0 Peptidase family M54 ANAPC3 PF12895.7 ABX12882.1 - 0.029 14.6 0.0 0.7 10.2 0.0 2.7 2 1 1 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MCM6_C PF18263.1 ABX12882.1 - 0.046 14.0 0.3 0.11 12.7 0.3 1.6 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Reprolysin_2 PF13574.6 ABX12882.1 - 0.058 13.3 0.1 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 ABX12882.1 - 0.06 12.3 0.1 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 Peptidase M66 TPR_11 PF13414.6 ABX12882.1 - 0.094 12.4 0.5 7.2 6.4 0.1 3.1 2 1 1 3 3 3 0 TPR repeat Peptidase_M43 PF05572.13 ABX12882.1 - 0.18 11.7 0.5 0.45 10.4 0.0 1.9 2 0 0 2 2 1 0 Pregnancy-associated plasma protein-A TPR_15 PF13429.6 ABX12882.1 - 0.24 10.6 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Metallopep PF12044.8 ABX12882.1 - 0.41 9.2 1.4 0.54 8.8 0.0 1.8 2 0 0 2 2 2 0 Putative peptidase family TFIIB PF00382.19 ABX12883.1 - 5.8e-33 112.8 6.2 3.7e-16 58.9 0.2 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ABX12883.1 - 2.6e-13 49.2 1.0 4.9e-13 48.4 1.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 ABX12883.1 - 7.1e-05 22.6 0.6 0.00036 20.3 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain OrfB_Zn_ribbon PF07282.11 ABX12883.1 - 0.00049 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain TFIIB_C_1 PF18542.1 ABX12883.1 - 0.0017 18.3 0.6 0.0046 16.9 0.6 1.7 1 0 0 1 1 1 1 Transcription factor IIB C-terminal module 1 Ribosomal_S27e PF01667.17 ABX12883.1 - 0.073 12.8 0.8 0.18 11.6 0.8 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 Prim_Zn_Ribbon PF08273.12 ABX12883.1 - 0.074 13.3 2.1 0.18 12.1 2.1 1.6 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase RB_B PF01857.20 ABX12883.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Lar_restr_allev PF14354.6 ABX12883.1 - 0.35 11.3 1.9 0.5 10.8 0.5 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 ABX12883.1 - 4.8 7.0 6.4 6.3 6.7 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Pribosyltran PF00156.27 ABX12884.1 - 6.5e-09 35.5 0.0 0.0014 18.2 0.0 2.1 1 1 1 2 2 2 2 Phosphoribosyl transferase domain PHA_synth_III_E PF09712.10 ABX12886.1 - 7.6e-14 51.5 0.2 9.3e-14 51.2 0.2 1.1 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Cnn_1N PF07989.11 ABX12886.1 - 0.00016 21.7 2.9 0.39 10.9 2.0 2.3 2 0 0 2 2 2 2 Centrosomin N-terminal motif 1 Bacillus_HBL PF05791.11 ABX12886.1 - 0.0022 17.8 3.2 0.081 12.7 0.3 2.4 2 0 0 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) DUF2408 PF10303.9 ABX12886.1 - 0.0025 18.4 4.2 0.0036 17.9 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) DUF4763 PF15960.5 ABX12886.1 - 0.016 14.5 3.2 2.1 7.6 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Seryl_tRNA_N PF02403.22 ABX12886.1 - 0.067 13.4 6.9 3 8.1 4.1 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 ABX12886.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF3150 PF11348.8 ABX12886.1 - 0.13 11.5 3.6 0.48 9.6 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3150) GAT PF03127.14 ABX12886.1 - 0.5 10.7 4.4 2.3 8.6 0.3 2.8 2 1 1 3 3 3 0 GAT domain IFP_35_N PF07334.13 ABX12886.1 - 0.54 10.4 8.0 0.35 11.0 1.8 2.5 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus CCDC-167 PF15188.6 ABX12886.1 - 0.69 10.3 6.1 0.79 10.1 1.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 GBP_repeat PF02526.14 ABX12886.1 - 1.5 8.6 3.7 5.2 6.9 0.2 2.9 3 0 0 3 3 3 0 Glycophorin-binding protein Abhydrolase_1 PF00561.20 ABX12887.1 - 8.8e-15 55.0 0.0 1e-14 54.8 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABX12887.1 - 2.8e-14 53.0 0.0 4.5e-13 49.0 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PhaC_N PF07167.13 ABX12887.1 - 3.6e-13 49.5 0.1 7.2e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus DUF3141 PF11339.8 ABX12887.1 - 1.1e-07 30.7 0.0 1.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3141) DLH PF01738.18 ABX12887.1 - 4.1e-05 23.3 0.0 0.00033 20.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family PHB_depo_C PF06850.11 ABX12887.1 - 0.0016 17.9 0.0 0.013 14.9 0.0 2.2 1 1 1 2 2 2 1 PHB de-polymerase C-terminus BAAT_C PF08840.11 ABX12887.1 - 0.0029 17.6 0.0 0.0062 16.5 0.0 1.5 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1749 PF08538.10 ABX12887.1 - 0.027 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) LIP PF03583.14 ABX12887.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase ATG16 PF08614.11 ABX12888.1 - 0.0016 18.7 2.3 0.0024 18.2 2.3 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) REF PF05755.12 ABX12888.1 - 0.018 14.9 1.1 0.021 14.6 1.1 1.0 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) AATF-Che1 PF13339.6 ABX12888.1 - 0.051 14.3 1.8 0.071 13.8 1.8 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Mod_r PF07200.13 ABX12888.1 - 0.062 13.4 2.1 0.18 11.9 2.1 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein XPC-binding PF09280.11 ABX12888.1 - 0.1 12.3 1.0 1.1 9.1 1.0 2.4 1 1 0 1 1 1 0 XPC-binding domain DUF5339 PF17274.2 ABX12888.1 - 0.13 13.2 0.7 0.13 13.2 0.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5339) DUF2937 PF11157.8 ABX12888.1 - 0.15 11.7 3.1 5.9 6.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) DUF4473 PF14747.6 ABX12888.1 - 0.2 12.2 7.1 1 10.0 1.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4473) STAT_int PF02865.17 ABX12888.1 - 0.27 11.7 4.4 0.22 12.0 1.2 2.0 1 1 1 2 2 2 0 STAT protein, protein interaction domain MazE_antitoxin PF04014.18 ABX12889.1 - 0.00059 19.7 0.1 0.001 19.0 0.1 1.4 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin DUF148 PF02520.17 ABX12889.1 - 0.0032 17.6 0.8 0.0071 16.4 0.9 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF148 CortBP2 PF09727.9 ABX12889.1 - 0.023 14.6 0.1 0.028 14.3 0.1 1.1 1 0 0 1 1 1 0 Cortactin-binding protein-2 GAT PF03127.14 ABX12889.1 - 0.027 14.8 0.2 0.039 14.3 0.2 1.3 1 0 0 1 1 1 0 GAT domain MraZ PF02381.18 ABX12889.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like Abhydrolase_1 PF00561.20 ABX12890.1 - 5.8e-30 104.8 0.1 2.3e-23 83.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABX12890.1 - 7.1e-19 69.3 0.0 1e-18 68.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABX12890.1 - 2e-18 66.5 0.0 2.7e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ABX12890.1 - 0.00019 21.3 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 ABX12890.1 - 0.001 18.8 0.0 0.98 9.2 0.0 2.6 1 1 2 3 3 3 2 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 ABX12890.1 - 0.0033 17.3 0.0 0.077 12.9 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.10 ABX12890.1 - 0.016 15.3 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.14 ABX12890.1 - 0.023 13.4 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family NAAA-beta PF15508.6 ABX12890.1 - 0.083 13.2 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF3530 PF12048.8 ABX12890.1 - 0.087 12.2 0.1 0.18 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) PMSR PF01625.21 ABX12891.1 - 1.2e-66 223.7 0.5 1.3e-66 223.5 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Robl_LC7 PF03259.17 ABX12892.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Roadblock/LC7 domain Methyltransf_11 PF08241.12 ABX12893.1 - 2.2e-10 41.0 0.0 3.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX12893.1 - 1.1e-05 26.0 0.0 1.8e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABX12893.1 - 0.00022 21.1 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABX12893.1 - 0.001 18.9 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABX12893.1 - 0.0068 17.1 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ABX12893.1 - 0.14 11.5 0.0 0.39 10.0 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Tweety PF04906.13 ABX12894.1 - 0.39 9.3 4.7 0.94 8.1 0.0 2.6 2 0 0 2 2 2 0 Tweety FlxA PF14282.6 ABX12895.1 - 5.1e-05 23.2 15.3 0.0018 18.3 0.9 2.7 2 0 0 2 2 2 2 FlxA-like protein CorA PF01544.18 ABX12895.1 - 0.00017 21.0 2.1 0.043 13.1 0.0 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Tropomyosin PF00261.20 ABX12895.1 - 0.001 18.5 7.8 0.31 10.4 3.2 2.4 2 0 0 2 2 2 2 Tropomyosin DUF4094 PF13334.6 ABX12895.1 - 0.0028 18.0 4.0 0.12 12.8 0.2 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4094) TPR_MLP1_2 PF07926.12 ABX12895.1 - 0.0031 17.6 9.3 0.43 10.6 0.0 2.7 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein LPP PF04728.13 ABX12895.1 - 0.0042 17.4 5.5 1.4 9.3 1.2 3.5 3 0 0 3 3 3 1 Lipoprotein leucine-zipper DUF4140 PF13600.6 ABX12895.1 - 0.0076 16.7 10.3 0.17 12.4 1.1 3.5 2 2 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF2046 PF09755.9 ABX12895.1 - 0.011 15.0 13.2 0.033 13.4 6.2 2.6 3 0 0 3 3 2 0 Uncharacterized conserved protein H4 (DUF2046) ATG16 PF08614.11 ABX12895.1 - 0.012 15.8 7.8 0.81 9.9 2.7 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DASH_Spc19 PF08287.11 ABX12895.1 - 0.017 15.0 5.8 0.017 15.0 5.8 2.6 3 0 0 3 3 2 0 Spc19 Cnn_1N PF07989.11 ABX12895.1 - 0.018 15.2 0.4 0.018 15.2 0.4 3.1 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF16 PF01519.16 ABX12895.1 - 0.019 15.5 11.5 0.096 13.2 3.8 2.8 3 0 0 3 3 2 0 Protein of unknown function DUF16 Med9 PF07544.13 ABX12895.1 - 0.023 14.8 12.4 0.55 10.3 0.7 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 End3 PF12761.7 ABX12895.1 - 0.023 14.9 4.5 2.7 8.1 1.4 2.5 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 FlaC_arch PF05377.11 ABX12895.1 - 0.031 14.7 10.0 3.6 8.0 3.3 4.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) OmpH PF03938.14 ABX12895.1 - 0.031 14.6 7.8 1.7 8.9 3.7 2.9 4 0 0 4 4 2 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.20 ABX12895.1 - 0.039 13.9 20.8 0.077 13.0 3.2 4.7 5 0 0 5 5 5 0 Prefoldin subunit DUF2802 PF10975.8 ABX12895.1 - 0.047 13.8 3.7 12 6.1 0.8 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF2802) TMPIT PF07851.13 ABX12895.1 - 0.052 12.8 7.2 2.3 7.4 4.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein Spectrin PF00435.21 ABX12895.1 - 0.053 14.0 6.3 1.1 9.7 3.4 2.6 2 0 0 2 2 2 0 Spectrin repeat Fungal_trans_2 PF11951.8 ABX12895.1 - 0.055 12.3 1.8 0.94 8.2 0.7 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain ADIP PF11559.8 ABX12895.1 - 0.056 13.5 11.4 2.1 8.4 6.9 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 ABX12895.1 - 0.068 12.0 13.8 0.8 8.5 6.1 2.5 3 0 0 3 3 2 0 Spc7 kinetochore protein HalX PF08663.10 ABX12895.1 - 0.091 13.1 1.8 2.5 8.5 0.1 3.2 3 0 0 3 3 3 0 HalX domain EzrA PF06160.12 ABX12895.1 - 0.091 10.9 11.4 0.18 10.0 6.2 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.12 ABX12895.1 - 0.096 13.2 10.6 2.8 8.5 2.4 3.8 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein CSN5_C PF18323.1 ABX12895.1 - 0.098 13.6 8.2 4.4 8.3 0.0 3.0 3 0 0 3 3 2 0 Cop9 signalosome subunit 5 C-terminal domain DUF2019 PF09450.10 ABX12895.1 - 0.11 12.5 0.1 0.53 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) PHM7_cyt PF14703.6 ABX12895.1 - 0.12 12.6 3.0 2.3 8.4 0.0 3.5 1 1 2 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter 3-PAP PF12578.8 ABX12895.1 - 0.12 12.1 4.0 17 5.1 0.2 3.3 3 0 0 3 3 3 0 Myotubularin-associated protein Vps51 PF08700.11 ABX12895.1 - 0.14 12.3 7.8 0.63 10.2 1.0 3.8 3 0 0 3 3 3 0 Vps51/Vps67 CCDC-167 PF15188.6 ABX12895.1 - 0.14 12.5 10.4 0.53 10.7 0.4 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.12 ABX12895.1 - 0.16 12.0 5.4 4.2 7.4 2.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TraF_2 PF13729.6 ABX12895.1 - 0.16 11.3 1.7 2.2 7.6 0.6 2.2 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein Atg14 PF10186.9 ABX12895.1 - 0.17 11.0 15.9 0.072 12.2 0.4 2.6 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 ABX12895.1 - 0.18 10.8 6.8 1.1 8.1 1.9 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 XhlA PF10779.9 ABX12895.1 - 0.19 11.9 18.2 1.2 9.4 2.9 4.3 3 2 1 4 4 4 0 Haemolysin XhlA Pannexin_like PF12534.8 ABX12895.1 - 0.19 10.8 2.1 0.21 10.7 0.6 1.7 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 DUF4407 PF14362.6 ABX12895.1 - 0.21 10.9 5.6 1.4 8.2 0.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Uds1 PF15456.6 ABX12895.1 - 0.23 11.6 8.8 0.18 11.9 0.8 3.5 4 0 0 4 4 3 0 Up-regulated During Septation Csm1_N PF18504.1 ABX12895.1 - 0.31 11.4 11.3 12 6.3 0.0 3.9 3 1 0 3 3 3 0 Csm1 N-terminal domain NleF_casp_inhib PF16809.5 ABX12895.1 - 0.34 10.8 5.8 1.2 9.1 1.9 3.0 2 1 1 3 3 3 0 NleF caspase inhibitor AAA_23 PF13476.6 ABX12895.1 - 0.38 11.2 10.2 0.69 10.4 1.3 2.4 2 1 0 2 2 2 0 AAA domain LidA_Long_CC PF18641.1 ABX12895.1 - 0.44 10.6 8.1 0.61 10.1 4.1 2.4 2 0 0 2 2 2 0 LidA long coiled-coil domain Syntaxin-18_N PF10496.9 ABX12895.1 - 0.56 10.5 7.2 1.5 9.1 4.3 3.0 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Macoilin PF09726.9 ABX12895.1 - 0.57 8.7 13.5 1.7 7.1 13.5 1.8 1 1 0 1 1 1 0 Macoilin family Ax_dynein_light PF10211.9 ABX12895.1 - 0.66 9.9 11.1 2.1 8.3 2.0 2.7 3 0 0 3 3 2 0 Axonemal dynein light chain V_ATPase_I PF01496.19 ABX12895.1 - 0.91 7.4 5.3 0.55 8.1 1.7 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family ABC_tran_CTD PF16326.5 ABX12895.1 - 1 9.7 19.2 0.8 10.0 4.8 3.7 3 1 0 3 3 3 0 ABC transporter C-terminal domain Gon7 PF08738.10 ABX12895.1 - 1.1 9.4 4.8 0.99 9.5 0.3 2.6 2 1 0 2 2 2 0 Gon7 family AKNA PF12443.8 ABX12895.1 - 1.2 9.8 11.0 8 7.2 0.8 3.3 2 1 0 2 2 2 0 AT-hook-containing transcription factor PCRF PF03462.18 ABX12895.1 - 1.7 8.4 6.6 30 4.4 0.0 2.4 2 0 0 2 2 2 0 PCRF domain DUF2203 PF09969.9 ABX12895.1 - 1.8 9.3 7.4 21 5.8 1.5 2.9 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2203) Takusan PF04822.13 ABX12895.1 - 1.9 8.4 9.8 0.56 10.1 4.5 2.4 2 0 0 2 2 2 0 Takusan DUF2730 PF10805.8 ABX12895.1 - 1.9 8.6 6.7 7.9 6.6 1.1 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF2730) Dynamitin PF04912.14 ABX12895.1 - 2 7.7 15.6 2.9 7.1 5.9 2.5 2 1 0 2 2 2 0 Dynamitin Sec8_exocyst PF04048.14 ABX12895.1 - 2 8.3 11.1 7.4 6.5 3.7 2.8 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain GrpE PF01025.19 ABX12895.1 - 2.1 8.0 10.9 2.4 7.8 3.8 2.8 2 1 0 2 2 2 0 GrpE Tho2 PF11262.8 ABX12895.1 - 2.1 7.5 7.5 1.4 8.0 2.4 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Fib_alpha PF08702.10 ABX12895.1 - 2.2 8.5 10.4 7.9 6.7 0.2 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 ABX12895.1 - 2.2 9.0 9.1 19 6.0 1.2 3.5 2 1 1 3 3 3 0 SlyX Lzipper-MIP1 PF14389.6 ABX12895.1 - 2.3 8.6 12.0 14 6.0 3.7 3.9 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 APG6_N PF17675.1 ABX12895.1 - 2.4 8.7 12.9 19 5.8 0.0 2.7 3 0 0 3 3 2 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 ABX12895.1 - 2.8 8.3 17.8 2.6 8.4 8.5 2.8 3 0 0 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Allexi_40kDa PF05549.11 ABX12895.1 - 3.2 7.2 11.8 6.8 6.1 0.7 2.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein TMF_TATA_bd PF12325.8 ABX12895.1 - 3.3 8.0 16.0 7.3 6.8 7.4 3.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 ABX12895.1 - 3.4 8.4 6.6 31 5.3 0.2 2.9 2 1 0 2 2 2 0 Initiation control protein YabA Swi5 PF07061.11 ABX12895.1 - 3.7 7.7 16.0 5.2 7.2 3.8 3.5 3 1 1 4 4 3 0 Swi5 DUF724 PF05266.14 ABX12895.1 - 4 7.2 13.4 4 7.2 3.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF724) COG2 PF06148.11 ABX12895.1 - 4.4 7.4 8.3 25 5.0 0.6 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc24 PF08286.11 ABX12895.1 - 5.9 7.2 14.0 7 6.9 5.6 3.2 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.15 ABX12895.1 - 6.4 6.6 12.3 7.5 6.4 2.2 3.6 4 0 0 4 4 3 0 Septum formation initiator PRKG1_interact PF15898.5 ABX12895.1 - 6.9 7.6 13.1 4.7 8.2 5.7 2.8 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 ABX12895.1 - 7.1 7.1 18.3 1.2 9.7 0.6 3.1 3 0 0 3 3 2 0 Cell division protein ZapB MIP-T3_C PF17749.1 ABX12895.1 - 8.4 6.3 13.1 2 8.4 0.1 3.5 3 1 1 4 4 3 0 Microtubule-binding protein MIP-T3 C-terminal region Tropomyosin_1 PF12718.7 ABX12895.1 - 9.6 6.3 15.1 4.4 7.4 6.8 2.7 3 0 0 3 3 2 0 Tropomyosin like Seryl_tRNA_N PF02403.22 ABX12895.1 - 9.8 6.5 25.0 11 6.3 0.4 4.3 3 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain HTH_24 PF13412.6 ABX12896.1 - 0.00035 20.1 0.8 0.0019 17.7 0.5 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 ABX12896.1 - 0.0021 17.7 0.1 0.0044 16.7 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_5 PF01022.20 ABX12896.1 - 0.025 14.5 0.1 0.061 13.2 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family AsnC_trans_reg PF01037.21 ABX12897.1 - 5.5e-13 48.7 0.0 6.3e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain ACT_4 PF13291.6 ABX12897.1 - 0.024 15.2 0.2 0.068 13.8 0.2 1.7 1 1 1 2 2 2 0 ACT domain NapD PF03927.13 ABX12897.1 - 0.054 13.6 0.0 0.069 13.2 0.0 1.1 1 0 0 1 1 1 0 NapD protein Transcrip_reg PF01709.20 ABX12897.1 - 0.098 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator FGase PF05013.12 ABX12899.1 - 5.9e-47 160.7 0.0 6.8e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase G_glu_transpept PF01019.21 ABX12900.1 - 5.6e-108 361.9 0.0 6.4e-108 361.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Ion_trans PF00520.31 ABX12901.1 - 1.8e-30 106.0 16.2 2.2e-30 105.7 16.2 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 ABX12901.1 - 1.7e-12 47.1 7.1 1.7e-12 47.1 7.1 2.3 3 0 0 3 3 3 1 Ion channel zf-ribbon_3 PF13248.6 ABX12901.1 - 0.093 12.2 0.4 0.15 11.5 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 ABX12901.1 - 0.093 12.9 0.2 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain CorA PF01544.18 ABX12902.1 - 7.4e-67 225.7 6.6 7.4e-67 225.7 6.6 2.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Tetraspanin PF00335.20 ABX12902.1 - 0.0078 16.0 6.3 0.15 11.7 0.4 2.5 2 0 0 2 2 2 2 Tetraspanin family DUF4795 PF16043.5 ABX12902.1 - 0.014 15.0 0.4 0.29 10.7 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) DUF2207 PF09972.9 ABX12902.1 - 0.24 10.1 16.6 0.36 9.6 0.3 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF21 PF01595.20 ABX12903.1 - 2.8e-50 170.4 0.1 4.1e-50 169.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 ABX12903.1 - 5.6e-17 61.5 1.3 1.3e-16 60.3 0.1 2.1 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 ABX12903.1 - 2.1e-16 60.1 1.3 2.4e-07 31.1 0.0 2.9 2 0 0 2 2 2 2 CBS domain Dala_Dala_lig_C PF07478.13 ABX12904.1 - 1.1e-31 110.0 0.0 1.9e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 ABX12904.1 - 1.2e-11 44.9 0.2 2.2e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 ABX12904.1 - 4.2e-11 42.7 2.8 7.5e-11 41.9 0.1 2.8 3 1 0 3 3 3 1 ATP-grasp domain Peptidase_M20 PF01546.28 ABX12904.1 - 1.6e-10 41.0 0.0 3.8e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 CPSase_L_D2 PF02786.17 ABX12904.1 - 1.2e-07 31.4 0.0 2.8e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 ABX12904.1 - 2e-05 24.3 0.2 0.00039 20.1 0.2 2.4 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.19 ABX12904.1 - 7e-05 22.7 0.3 0.00015 21.6 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 ABX12904.1 - 0.068 12.4 0.1 1.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Ribosomal_S30AE PF02482.19 ABX12904.1 - 0.096 13.5 0.2 0.49 11.2 0.2 2.2 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein TIR_2 PF13676.6 ABX12904.1 - 0.16 12.6 0.0 9.4 6.9 0.0 2.6 2 0 0 2 2 2 0 TIR domain Apolipoprotein PF01442.18 ABX12905.1 - 2e-05 24.6 10.7 2.9e-05 24.0 10.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain PIN_8 PF18476.1 ABX12905.1 - 0.05 13.5 11.6 0.072 12.9 11.6 1.1 1 0 0 1 1 1 0 PIN like domain DUF2678 PF10856.8 ABX12905.1 - 0.19 11.7 8.3 0.4 10.6 6.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Mitofilin PF09731.9 ABX12905.1 - 0.55 9.0 19.4 0.79 8.5 19.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DNA_primase_lrg PF04104.14 ABX12905.1 - 0.64 9.4 7.6 1 8.7 7.6 1.3 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Baculo_PEP_C PF04513.12 ABX12905.1 - 0.69 9.9 2.7 1.5 8.8 2.7 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 ABX12905.1 - 0.79 9.7 16.8 0.52 10.3 6.1 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) BshC PF10079.9 ABX12905.1 - 1.1 8.0 14.1 1.4 7.5 14.1 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF3810 PF12725.7 ABX12905.1 - 1.1 8.5 18.0 0.16 11.3 2.4 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3810) Z1 PF10593.9 ABX12905.1 - 1.2 8.5 8.7 1.2 8.6 7.5 1.6 2 0 0 2 2 2 0 Z1 domain DUF1690 PF07956.11 ABX12905.1 - 1.3 9.4 21.9 1.9 8.9 21.9 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Fzo_mitofusin PF04799.13 ABX12905.1 - 2.7 7.5 10.4 16 5.0 10.3 2.0 1 1 0 1 1 1 0 fzo-like conserved region HN PF00423.19 ABX12905.1 - 3.7 6.2 4.7 6.3 5.5 4.7 1.3 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase OmpH PF03938.14 ABX12905.1 - 3.8 7.9 22.1 6.2 7.2 22.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MlaE PF02405.16 ABX12906.1 - 0.0094 15.6 0.8 0.013 15.2 0.8 1.1 1 0 0 1 1 1 1 Permease MlaE Actin_micro PF17003.5 ABX12906.1 - 0.014 14.6 0.1 0.02 14.1 0.1 1.1 1 0 0 1 1 1 0 Putative actin-like family zf-Di19 PF05605.12 ABX12906.1 - 0.017 15.4 0.2 0.027 14.8 0.2 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Abhydrolase_9_N PF15420.6 ABX12906.1 - 0.057 13.4 0.1 0.06 13.3 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus CitMHS PF03600.16 ABX12906.1 - 0.11 11.7 1.0 0.14 11.4 1.0 1.1 1 0 0 1 1 1 0 Citrate transporter Colicin_V PF02674.16 ABX12906.1 - 0.15 12.0 3.9 0.19 11.7 3.9 1.1 1 0 0 1 1 1 0 Colicin V production protein Protocadherin PF08374.11 ABX12906.1 - 0.16 11.9 0.1 0.3 11.0 0.0 1.5 2 0 0 2 2 2 0 Protocadherin Flp_Fap PF04964.14 ABX12906.1 - 3.7 7.5 9.7 0.62 9.9 2.8 2.3 2 0 0 2 2 2 0 Flp/Fap pilin component MotA_ExbB PF01618.16 ABX12906.1 - 8.3 6.2 11.4 9.7 6.0 2.3 2.2 1 1 1 2 2 2 0 MotA/TolQ/ExbB proton channel family Nitroreductase PF00881.24 ABX12907.1 - 6e-26 91.5 0.0 2.4e-13 50.5 0.0 2.4 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 ABX12907.1 - 6.6e-08 32.4 0.8 0.0019 17.8 0.0 2.9 3 1 0 3 3 3 2 Putative TM nitroreductase DCP1 PF06058.13 ABX12907.1 - 0.051 13.5 0.9 0.58 10.1 0.4 2.7 3 1 0 3 3 3 0 Dcp1-like decapping family Usp PF00582.26 ABX12908.1 - 6.4e-28 98.0 0.9 1.1e-27 97.3 0.9 1.3 1 1 0 1 1 1 1 Universal stress protein family PI_PP_C PF18365.1 ABX12908.1 - 0.044 13.8 0.1 0.062 13.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain FAM25 PF15825.5 ABX12908.1 - 0.62 10.5 5.9 6.4 7.2 0.3 2.8 2 1 1 3 3 3 0 FAM25 family DUF5615 PF18480.1 ABX12909.1 - 0.097 12.4 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) DUF4423 PF14394.6 ABX12910.1 - 3.5e-05 23.6 0.0 0.00046 19.9 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4423) HTH_20 PF12840.7 ABX12910.1 - 0.00056 19.9 0.0 0.0016 18.5 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain DUF1724 PF08350.10 ABX12910.1 - 0.0024 17.9 0.2 0.0047 17.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1724) MarR_2 PF12802.7 ABX12910.1 - 0.0026 17.6 0.1 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 ABX12910.1 - 0.0077 16.1 0.1 2.9 7.9 0.0 2.6 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 ABX12910.1 - 0.012 15.8 0.9 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_Crp_2 PF13545.6 ABX12910.1 - 0.013 15.5 0.1 0.036 14.0 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_45 PF14947.6 ABX12910.1 - 0.072 13.1 0.1 0.84 9.7 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DUF3449 PF11931.8 ABX12910.1 - 0.097 12.5 0.2 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) MarR PF01047.22 ABX12910.1 - 0.22 11.5 0.9 13 5.8 0.1 2.4 2 0 0 2 2 2 0 MarR family DUF4377 PF14302.6 ABX12911.1 - 4.8e-27 93.8 0.6 2.1e-26 91.8 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4377) Kazal_1 PF00050.21 ABX12911.1 - 1.2e-09 38.0 0.1 4.2e-09 36.3 0.1 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 ABX12911.1 - 1.4e-05 25.1 3.0 2.2e-05 24.5 0.7 2.5 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain DUF2127 PF09900.9 ABX12912.1 - 0.17 12.1 17.7 0.05 13.9 10.1 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2127) DUF2270 PF10028.9 ABX12912.1 - 6.7 6.2 7.4 13 5.3 1.1 2.3 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2270) Aminotran_3 PF00202.21 ABX12913.1 - 1.2e-56 192.1 0.0 1.7e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III TPR_2 PF07719.17 ABX12915.1 - 1.5e-37 124.7 4.9 2.3e-05 24.1 0.0 7.2 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 ABX12915.1 - 1.8e-31 106.6 18.1 4.1e-07 29.5 0.0 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 ABX12915.1 - 3.5e-27 93.8 12.1 1.4e-06 27.8 0.0 6.8 2 1 5 7 7 7 6 TPR repeat TPR_17 PF13431.6 ABX12915.1 - 2.1e-25 87.2 8.1 7.2e-05 22.9 0.2 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 ABX12915.1 - 1.4e-22 78.4 0.0 0.23 12.4 0.0 7.1 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 ABX12915.1 - 2.7e-22 79.1 0.0 7.3e-08 32.9 0.0 4.9 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 ABX12915.1 - 1.9e-21 75.2 2.7 0.045 14.4 0.0 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 ABX12915.1 - 2.7e-19 67.7 15.6 9.8e-07 28.5 0.0 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 ABX12915.1 - 6.1e-18 65.1 7.8 3.5e-06 27.4 0.2 4.2 2 1 3 5 5 5 5 Tetratricopeptide repeat ANAPC3 PF12895.7 ABX12915.1 - 6.6e-18 64.7 4.1 4.4e-05 23.6 0.1 3.1 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ABX12915.1 - 7.5e-17 61.4 3.3 4.8e-06 26.8 0.6 5.3 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 ABX12915.1 - 4.1e-11 42.1 0.3 0.0039 17.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 ABX12915.1 - 7.5e-11 42.0 0.0 2.8e-05 24.2 0.0 3.9 1 1 4 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 ABX12915.1 - 4.5e-08 32.5 7.8 9.1e-05 21.6 0.7 3.2 1 1 3 4 4 4 2 NMDA receptor-regulated protein 1 MIT PF04212.18 ABX12915.1 - 6.6e-07 29.3 13.1 0.69 10.0 0.0 6.4 5 2 2 7 7 7 2 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 ABX12915.1 - 9.2e-07 28.6 7.2 0.044 13.7 1.1 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat Coatomer_E PF04733.14 ABX12915.1 - 9.8e-07 28.5 4.9 0.028 13.8 0.1 3.9 1 1 4 5 5 5 3 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 ABX12915.1 - 1.3e-06 28.4 6.0 0.23 11.5 0.0 5.8 4 2 2 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 ABX12915.1 - 7.3e-06 26.2 5.3 0.24 11.8 0.2 4.3 1 1 3 5 5 5 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 ABX12915.1 - 0.00019 21.4 0.3 2 8.6 0.0 4.0 2 2 3 5 5 5 1 Rapsyn N-terminal myristoylation and linker region Thioredoxin_6 PF13848.6 ABX12915.1 - 0.005 16.8 0.9 0.021 14.7 0.1 2.3 3 0 0 3 3 3 1 Thioredoxin-like domain TOM20_plant PF06552.12 ABX12915.1 - 0.0063 16.3 5.8 0.4 10.4 0.6 3.8 1 1 2 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 PknG_TPR PF16918.5 ABX12915.1 - 0.007 15.1 0.0 0.078 11.7 0.0 2.1 1 1 1 2 2 2 1 Protein kinase G tetratricopeptide repeat ANAPC5 PF12862.7 ABX12915.1 - 0.019 15.0 0.7 0.088 12.9 0.2 2.5 1 1 0 2 2 1 0 Anaphase-promoting complex subunit 5 ChAPs PF09295.10 ABX12915.1 - 0.022 13.8 1.7 0.15 11.0 0.3 2.0 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 ABX12915.1 - 0.028 14.1 0.0 0.64 9.7 0.0 2.6 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF247 PF03140.15 ABX12915.1 - 0.032 13.5 1.3 0.37 9.9 0.2 2.6 2 2 0 2 2 2 0 Plant protein of unknown function R2K_3 PF14243.6 ABX12915.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 TPR_4 PF07721.14 ABX12915.1 - 0.092 13.4 0.0 11 7.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 ABX12915.1 - 0.093 13.2 2.7 33 4.9 0.1 3.8 1 1 4 5 5 5 0 Alkyl sulfatase dimerisation RAP-1 PF03085.15 ABX12915.1 - 0.11 12.2 2.2 0.2 11.4 0.5 2.1 2 1 1 3 3 2 0 Rhoptry-associated protein 1 (RAP-1) DUF4919 PF16266.5 ABX12915.1 - 0.14 12.0 2.7 10 6.0 0.1 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4919) TPR_3 PF07720.12 ABX12915.1 - 0.25 11.4 9.8 7.7 6.6 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF5113 PF17140.4 ABX12915.1 - 0.36 10.6 2.3 26 4.6 0.1 3.4 2 2 0 3 3 3 0 Domain of unknown function (DUF5113) PPR PF01535.20 ABX12915.1 - 0.59 10.5 6.2 19 5.8 0.1 5.5 7 0 0 7 7 7 0 PPR repeat RPN6_N PF18055.1 ABX12915.1 - 2.7 8.4 8.1 5.1 7.5 0.1 3.5 1 1 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Toprim_Crpt PF13342.6 ABX12916.1 - 0.017 15.1 0.3 0.061 13.3 0.3 1.9 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase ComJ PF11033.8 ABX12916.1 - 0.037 13.7 0.2 0.44 10.2 0.0 2.3 2 1 0 2 2 2 0 Competence protein J (ComJ) SHOCT PF09851.9 ABX12917.1 - 2.6e-08 33.3 2.4 6.5e-08 32.1 2.4 1.8 1 0 0 1 1 1 1 Short C-terminal domain DUF2680 PF10925.8 ABX12917.1 - 0.28 11.2 5.2 0.35 10.9 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2680) RRF PF01765.19 ABX12917.1 - 0.62 10.0 11.5 2.5 8.0 8.1 2.5 1 1 1 2 2 2 0 Ribosome recycling factor Cupin_2 PF07883.11 ABX12918.1 - 2.1e-07 30.6 0.2 9.5e-07 28.4 0.2 1.9 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ABX12918.1 - 1.9e-06 27.6 0.0 2.1e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Cupin Auxin_BP PF02041.16 ABX12918.1 - 2.1e-05 24.2 0.1 2.5e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 Auxin binding protein Cupin_8 PF13621.6 ABX12918.1 - 0.0024 17.6 0.1 0.0077 16.0 0.0 1.6 1 1 1 2 2 2 1 Cupin-like domain AraC_binding PF02311.19 ABX12918.1 - 0.029 14.3 0.1 0.044 13.7 0.1 1.3 1 1 0 1 1 1 0 AraC-like ligand binding domain FHA PF00498.26 ABX12918.1 - 0.071 13.5 0.4 0.11 12.9 0.4 1.5 1 1 0 1 1 1 0 FHA domain Cupin_2 PF07883.11 ABX12919.1 - 8.7e-15 54.2 0.0 2.1e-14 52.9 0.0 1.6 2 0 0 2 2 2 1 Cupin domain MannoseP_isomer PF01050.18 ABX12919.1 - 3.2e-08 33.6 0.0 3.7e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Ectoine_synth PF06339.12 ABX12919.1 - 7.1e-06 26.2 0.0 8.4e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Ectoine synthase AraC_binding PF02311.19 ABX12919.1 - 7.6e-05 22.6 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 ABX12919.1 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 ABX12919.1 - 0.00036 20.2 0.0 0.00056 19.6 0.0 1.3 1 1 0 1 1 1 1 Cupin GPI PF06560.11 ABX12919.1 - 0.0025 17.1 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) EutQ PF06249.12 ABX12919.1 - 0.0032 17.3 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ CENP-C_C PF11699.8 ABX12919.1 - 0.017 15.3 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like Cupin_5 PF06172.11 ABX12919.1 - 0.096 12.9 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Cupin superfamily (DUF985) T6PP_N PF18572.1 ABX12919.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DnaJ PF00226.31 ABX12920.1 - 4.8e-16 58.6 4.7 1.3e-15 57.2 4.7 1.7 1 0 0 1 1 1 1 DnaJ domain Fer4_13 PF13370.6 ABX12920.1 - 8.1e-10 39.1 2.4 2.8e-09 37.4 2.4 2.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 ABX12920.1 - 3.2e-05 24.6 5.3 0.00023 21.9 5.3 2.3 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 ABX12920.1 - 0.00082 19.4 4.3 0.0013 18.8 1.0 2.5 2 0 0 2 2 2 1 Divergent 4Fe-4S mono-cluster DUF2315 PF10231.9 ABX12920.1 - 0.0057 16.7 2.9 0.0057 16.7 2.9 2.2 1 1 1 2 2 2 1 Apoptogenic protein 1 RPT PF13446.6 ABX12920.1 - 0.017 15.0 0.1 0.061 13.3 0.1 1.9 2 0 0 2 2 2 0 A repeated domain in UCH-protein Fer4 PF00037.27 ABX12920.1 - 0.32 10.9 10.2 0.87 9.5 5.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 ABX12920.1 - 0.32 11.1 4.5 0.28 11.3 0.4 2.2 1 1 2 3 3 3 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S HIT PF01230.23 ABX12921.1 - 8.6e-23 80.9 1.5 1.1e-22 80.6 1.5 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ABX12921.1 - 2e-12 47.6 1.1 2.6e-12 47.2 1.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 ABX12921.1 - 2.2e-05 24.3 0.9 2.6e-05 24.1 0.9 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 ABX12921.1 - 0.00095 18.9 0.1 0.0013 18.5 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain Urocanase_C PF17392.2 ABX12921.1 - 0.083 12.3 0.0 0.098 12.1 0.0 1.1 1 0 0 1 1 1 0 Urocanase C-terminal domain SH3_3 PF08239.11 ABX12922.1 - 0.13 12.5 0.2 0.71 10.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain ATP1G1_PLM_MAT8 PF02038.16 ABX12922.1 - 0.22 11.0 2.2 0.36 10.3 2.2 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family zf-C2H2_4 PF13894.6 ABX12923.1 - 0.001 19.7 0.9 0.0014 19.3 0.9 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 ABX12923.1 - 0.0023 18.3 1.5 0.0033 17.8 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-BED PF02892.15 ABX12923.1 - 0.0033 17.4 0.6 0.0048 16.9 0.6 1.3 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_2 PF12756.7 ABX12923.1 - 0.017 15.4 0.1 0.018 15.4 0.1 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-CpG_bind_C PF12269.8 ABX12923.1 - 0.043 13.6 0.1 0.046 13.5 0.1 1.0 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain 3HCDH_N PF02737.18 ABX12924.1 - 3.1e-66 222.7 0.4 5.5e-66 221.9 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ABX12924.1 - 1.2e-34 118.8 0.1 1.1e-24 86.9 0.0 2.9 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 ABX12924.1 - 1.9e-05 24.7 0.2 4.6e-05 23.4 0.2 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 ABX12924.1 - 4.4e-05 23.7 0.0 9.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ABX12924.1 - 0.0089 16.6 1.0 0.044 14.4 1.0 2.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF4078 PF13300.6 ABX12924.1 - 0.02 15.2 0.4 0.036 14.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) IlvN PF07991.12 ABX12924.1 - 1.2 8.7 4.3 57 3.2 4.3 2.4 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain SpoVIF PF14069.6 ABX12925.1 - 0.014 15.2 0.9 0.24 11.2 0.2 2.2 1 1 1 2 2 2 0 Stage VI sporulation protein F SapB_1 PF05184.15 ABX12925.1 - 0.031 14.3 0.3 0.097 12.7 0.1 2.0 2 0 0 2 2 2 0 Saposin-like type B, region 1 HCR PF07111.12 ABX12925.1 - 0.13 10.3 0.0 0.14 10.2 0.0 1.0 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) LDcluster4 PF18306.1 ABX12926.1 - 9.1e-47 158.6 1.9 1e-46 158.4 1.9 1.0 1 0 0 1 1 1 1 SLOG cluster4 family Lysine_decarbox PF03641.14 ABX12926.1 - 7.4e-05 22.9 0.0 0.00019 21.5 0.0 1.8 1 1 0 1 1 1 1 Possible lysine decarboxylase DNA_processg_A PF02481.15 ABX12926.1 - 0.0006 19.1 0.7 0.0048 16.2 0.1 2.2 3 0 0 3 3 3 1 DNA recombination-mediator protein A DAGK_cat PF00781.24 ABX12926.1 - 0.0013 18.4 1.9 0.027 14.1 0.0 2.2 1 1 1 2 2 2 1 Diacylglycerol kinase catalytic domain Thi4 PF01946.17 ABX12926.1 - 0.013 14.8 1.0 0.28 10.4 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Ribosomal_S14 PF00253.21 ABX12927.1 - 0.00091 18.9 0.9 0.22 11.3 0.4 2.8 2 1 0 2 2 2 2 Ribosomal protein S14p/S29e zf-C4pol PF14260.6 ABX12927.1 - 0.0063 16.9 10.3 1.1 9.7 0.5 3.2 3 0 0 3 3 3 3 C4-type zinc-finger of DNA polymerase delta DUF4428 PF14471.6 ABX12927.1 - 0.011 15.7 2.9 0.011 15.7 2.9 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4428) zf-NADH-PPase PF09297.11 ABX12927.1 - 0.092 12.4 0.1 0.092 12.4 0.1 2.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Cytochrome_C7 PF14522.6 ABX12927.1 - 0.11 12.5 13.8 28 4.8 12.0 3.0 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c Prok-RING_4 PF14447.6 ABX12927.1 - 4 7.4 18.6 0.82 9.6 0.6 4.4 5 0 0 5 5 5 0 Prokaryotic RING finger family 4 Cytochrom_c3_2 PF14537.6 ABX12927.1 - 4.6 7.8 16.7 1.8 9.1 8.0 3.2 1 1 1 2 2 2 0 Cytochrome c3 DNA_RNApol_7kD PF03604.13 ABX12928.1 - 0.00061 19.4 1.2 0.001 18.7 1.2 1.4 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf_UBZ PF18439.1 ABX12928.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Ribosomal_S10 PF00338.22 ABX12929.1 - 8.5e-23 80.4 0.0 9.4e-23 80.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CTX_RstB PF07459.11 ABX12929.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 CTX phage RstB protein GTP_EFTU PF00009.27 ABX12930.1 - 1.7e-46 158.2 0.1 2.4e-46 157.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ABX12930.1 - 6.4e-37 126.3 0.4 2.5e-36 124.4 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ABX12930.1 - 1.1e-16 60.9 0.8 4.2e-16 59.1 0.8 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 ABX12930.1 - 0.00022 21.1 0.7 0.00051 19.9 0.7 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 FBPase_3 PF01950.16 ABX12931.1 - 2.5e-152 507.3 0.1 2.8e-152 507.1 0.1 1.0 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase MASE3 PF17159.4 ABX12932.1 - 0.0048 16.5 1.4 0.0067 16.1 1.4 1.1 1 0 0 1 1 1 1 Membrane-associated sensor domain YrhC PF14143.6 ABX12932.1 - 0.0064 16.6 1.7 0.013 15.6 1.7 1.7 1 0 0 1 1 1 1 YrhC-like protein DNA_ligase_A_M PF01068.21 ABX12933.1 - 2.9e-59 200.2 2.5 2.9e-59 200.1 0.8 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ABX12933.1 - 4e-37 128.2 1.3 7.7e-37 127.3 1.3 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ABX12933.1 - 3e-22 79.1 0.0 5.7e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 ABX12933.1 - 9.4e-08 32.5 0.3 2.2e-07 31.3 0.3 1.7 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 ABX12933.1 - 0.013 15.4 0.1 3.6 7.4 0.2 3.3 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.6 ABX12933.1 - 0.16 12.0 0.1 0.73 9.9 0.0 2.1 2 0 0 2 2 2 0 DNA ligase OB-like domain PhoU_div PF01865.16 ABX12934.1 - 1.2e-19 70.5 9.7 1.4e-19 70.3 9.7 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 PhoU PF01895.19 ABX12934.1 - 0.00086 19.7 11.6 0.0096 16.4 2.1 2.9 2 1 1 3 3 3 2 PhoU domain ELL PF10390.9 ABX12934.1 - 0.047 13.2 0.5 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL WD40_alt PF14077.6 ABX12934.1 - 0.14 12.1 0.3 0.14 12.1 0.3 2.5 3 0 0 3 3 3 0 Alternative WD40 repeat motif MCPsignal PF00015.21 ABX12934.1 - 0.49 10.2 9.9 1.4 8.7 7.9 2.7 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 ABX12934.1 - 0.64 10.3 10.0 0.69 10.2 0.3 3.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Lzipper-MIP1 PF14389.6 ABX12934.1 - 1.3 9.4 9.0 0.44 10.9 1.9 2.9 2 2 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Noelin-1 PF12308.8 ABX12934.1 - 1.5 8.8 5.9 4.5 7.3 0.9 2.7 2 1 0 2 2 2 0 Neurogenesis glycoprotein S6OS1 PF15676.5 ABX12934.1 - 6 5.2 9.4 0.39 9.1 3.0 2.0 2 1 0 2 2 2 0 Six6 opposite strand transcript 1 family CENP-H PF05837.12 ABX12934.1 - 7.2 7.1 11.5 1.6 9.1 2.9 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF2203 PF09969.9 ABX12934.1 - 7.3 7.3 8.5 4.7 8.0 1.2 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) tRNA_int_endo PF01974.17 ABX12935.1 - 4.4e-28 97.2 0.0 6.9e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 ABX12935.1 - 8.4e-21 73.4 0.0 1.5e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain fn3 PF00041.21 ABX12936.1 - 3.8e-47 158.6 6.9 8.9e-15 54.8 0.3 3.5 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 ABX12936.1 - 7.7e-13 48.8 10.7 0.0015 19.1 0.7 3.9 3 0 0 3 3 3 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 ABX12936.1 - 0.00011 22.6 0.9 2.7 8.4 0.0 3.4 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2369) FHA PF00498.26 ABX12936.1 - 0.00015 22.0 0.0 3.1 8.2 0.0 3.7 3 0 0 3 3 3 1 FHA domain Glyco_hydro_36C PF16874.5 ABX12936.1 - 0.0046 17.4 0.0 53 4.4 0.0 3.4 3 0 0 3 3 3 0 Glycosyl hydrolase family 36 C-terminal domain Copper-bind PF00127.20 ABX12936.1 - 0.013 16.0 0.0 0.039 14.4 0.0 1.8 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX12936.1 - 0.026 14.6 0.0 0.12 12.6 0.0 2.2 1 0 0 1 1 1 0 Cupredoxin-like domain MG2 PF01835.19 ABX12936.1 - 0.033 14.6 0.0 0.14 12.6 0.0 2.1 1 0 0 1 1 1 0 MG2 domain CytadhesinP1 PF12378.8 ABX12936.1 - 0.096 12.9 0.5 0.57 10.4 0.0 2.6 4 0 0 4 4 4 0 Trypsin-sensitive surface-exposed protein adh_short PF00106.25 ABX12939.1 - 4.6e-42 143.7 0.1 3.4e-34 118.0 0.1 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ABX12939.1 - 1.2e-37 129.7 0.1 2.5e-25 89.4 0.0 3.7 3 1 1 4 4 4 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABX12939.1 - 2.1e-14 53.9 0.1 4.8e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 ABX12939.1 - 3.3e-06 26.7 0.0 1.9e-05 24.3 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ABX12939.1 - 0.00099 18.3 0.2 0.0043 16.2 0.1 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ABX12939.1 - 0.004 16.6 0.1 0.026 13.9 0.0 2.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 ABX12939.1 - 0.054 13.5 0.8 0.39 10.8 0.1 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ABX12939.1 - 0.06 13.2 0.3 0.06 13.2 0.3 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Response_reg PF00072.24 ABX12941.1 - 2.1e-17 63.3 1.4 2.4e-17 63.1 1.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 ABX12942.1 - 6.4e-12 45.6 0.2 3.3e-11 43.4 0.2 2.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ABX12942.1 - 7.4e-12 45.3 0.0 1.6e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold HAMP PF00672.25 ABX12942.1 - 1.4e-08 35.0 0.0 2.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 HAMP domain PAS_3 PF08447.12 ABX12942.1 - 2.5e-07 30.9 0.5 6.5e-07 29.6 0.1 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 ABX12942.1 - 0.00093 19.2 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_6 PF08348.11 ABX12942.1 - 0.35 10.8 3.4 0.96 9.3 0.0 3.0 3 1 0 3 3 3 0 YheO-like PAS domain DUF2178 PF09946.9 ABX12942.1 - 2 8.6 5.1 1.6 8.9 0.1 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) fn3 PF00041.21 ABX12943.1 - 1.1e-32 112.2 21.4 3.8e-13 49.6 3.9 4.3 4 0 0 4 4 4 3 Fibronectin type III domain NHL PF01436.21 ABX12943.1 - 7.9e-31 104.5 8.5 1.4e-06 28.0 0.0 7.0 7 0 0 7 7 7 5 NHL repeat DUF5128 PF17170.4 ABX12943.1 - 4.6e-15 55.6 17.6 1.4e-05 24.5 1.7 5.1 3 2 1 4 4 4 4 6-bladed beta-propeller Lactonase PF10282.9 ABX12943.1 - 2.3e-09 37.0 5.1 0.00093 18.6 0.0 5.1 6 0 0 6 6 6 3 Lactonase, 7-bladed beta-propeller Pur_ac_phosph_N PF16656.5 ABX12943.1 - 1.1e-08 35.5 24.2 0.001 19.6 4.9 4.3 4 1 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain SGL PF08450.12 ABX12943.1 - 4.1e-07 29.8 8.5 0.04 13.5 0.0 4.6 2 2 1 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ABX12943.1 - 3.4e-05 24.0 0.0 1.3 9.3 0.0 5.3 5 0 0 5 5 5 1 Arylesterase fn3_4 PF16794.5 ABX12943.1 - 0.0082 16.1 0.3 1.6 8.7 0.0 3.8 3 1 0 3 3 3 1 Fibronectin-III type domain He_PIG PF05345.12 ABX12943.1 - 0.089 13.0 0.0 0.089 13.0 0.0 5.2 6 0 0 6 6 6 0 Putative Ig domain F5_F8_type_C PF00754.25 ABX12943.1 - 2 8.5 6.7 0.63 10.2 1.8 2.6 2 1 1 3 3 3 0 F5/8 type C domain TauE PF01925.19 ABX12944.1 - 1.6e-51 175.3 33.6 1.8e-51 175.0 33.6 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF1516 PF07457.11 ABX12944.1 - 0.35 11.1 5.5 0.12 12.5 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) PPO1_DWL PF12142.8 ABX12945.1 - 0.0099 15.6 0.4 0.18 11.6 0.0 2.2 2 0 0 2 2 2 1 Polyphenol oxidase middle domain DUF192 PF02643.15 ABX12946.1 - 8.9e-28 96.3 0.1 1.4e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 Fe_dep_repress PF01325.19 ABX12949.1 - 1.5e-19 70.0 1.0 2.3e-19 69.3 1.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.15 ABX12949.1 - 2.8e-14 52.9 0.0 5.3e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain DUF4423 PF14394.6 ABX12949.1 - 0.00011 21.9 0.0 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) MarR_2 PF12802.7 ABX12949.1 - 0.00035 20.4 0.0 0.00055 19.8 0.0 1.3 1 0 0 1 1 1 1 MarR family LexA_DNA_bind PF01726.16 ABX12949.1 - 0.001 18.8 0.0 0.0035 17.1 0.0 1.9 3 0 0 3 3 2 1 LexA DNA binding domain TrmB PF01978.19 ABX12949.1 - 0.0012 18.6 0.1 0.0022 17.9 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HipN PF18253.1 ABX12949.1 - 0.0026 17.4 0.1 0.0052 16.4 0.1 1.5 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain HTH_27 PF13463.6 ABX12949.1 - 0.004 17.6 0.0 0.015 15.7 0.0 2.0 2 1 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 ABX12949.1 - 0.0047 16.4 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 ABX12949.1 - 0.006 16.5 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 ABX12949.1 - 0.0073 16.2 0.0 0.02 14.8 0.0 1.7 2 0 0 2 2 2 1 MarR family WYL_3 PF18488.1 ABX12949.1 - 0.011 16.1 0.3 0.085 13.2 0.1 2.2 2 0 0 2 2 2 0 WYL domain DUF2250 PF10007.9 ABX12949.1 - 0.022 14.9 0.1 0.04 14.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_IclR PF09339.10 ABX12949.1 - 0.032 14.0 0.5 0.059 13.2 0.0 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_6 PF01418.17 ABX12949.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_12 PF08461.10 ABX12949.1 - 0.076 13.0 0.1 0.19 11.7 0.1 1.7 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_5 PF01022.20 ABX12949.1 - 0.1 12.5 0.1 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family PAX PF00292.18 ABX12949.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain Rrf2 PF02082.20 ABX12949.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Ribosomal_S19e PF01090.19 ABX12949.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein S19e T2SSE PF00437.20 ABX12950.1 - 5.4e-11 42.1 0.0 9.1e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein KH_1 PF00013.29 ABX12950.1 - 4.5e-09 36.0 0.4 2.4e-08 33.7 0.0 2.5 2 0 0 2 2 1 1 KH domain KH_2 PF07650.17 ABX12950.1 - 1.1e-06 28.3 0.6 3.6e-06 26.7 0.1 2.1 2 0 0 2 2 1 1 KH domain PIN_4 PF13638.6 ABX12950.1 - 3e-05 24.3 0.8 0.00014 22.1 0.1 2.5 2 1 0 2 2 2 1 PIN domain PIN PF01850.21 ABX12950.1 - 4.1e-05 24.1 0.0 0.00013 22.5 0.0 1.8 1 0 0 1 1 1 1 PIN domain KH_5 PF13184.6 ABX12950.1 - 8.1e-05 22.6 1.5 0.00021 21.3 0.3 2.4 2 0 0 2 2 2 1 NusA-like KH domain ABC_tran PF00005.27 ABX12950.1 - 0.00029 21.4 0.1 0.032 14.7 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 ABX12950.1 - 0.00029 21.2 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 ABX12950.1 - 0.00077 19.1 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ABX12950.1 - 0.0013 18.9 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ABX12950.1 - 0.0015 18.5 0.0 0.0052 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABX12950.1 - 0.0016 18.7 0.0 0.044 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 ABX12950.1 - 0.002 17.2 0.0 0.0042 16.1 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 ABX12950.1 - 0.002 18.7 0.0 0.0086 16.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 ABX12950.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 ABX12950.1 - 0.0066 16.2 0.1 0.076 12.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain PIN_9 PF18477.1 ABX12950.1 - 0.017 15.5 0.4 0.24 11.7 0.4 2.5 1 1 0 1 1 1 0 PIN like domain Viral_helicase1 PF01443.18 ABX12950.1 - 0.025 14.3 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 ABX12950.1 - 0.029 13.6 0.0 0.072 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 ABX12950.1 - 0.04 13.1 0.0 0.094 11.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 ABX12950.1 - 0.051 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 ABX12950.1 - 0.056 13.3 0.0 0.19 11.6 0.0 2.0 1 0 0 1 1 1 0 NTPase KTI12 PF08433.10 ABX12950.1 - 0.069 12.6 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 ABX12950.1 - 0.081 13.1 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ABX12950.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 NACHT domain MOEP19 PF16005.5 ABX12950.1 - 0.15 12.1 0.1 4.2 7.4 0.0 2.8 2 0 0 2 2 2 0 KH-like RNA-binding domain PmbA_TldD PF01523.16 ABX12951.1 - 3e-59 201.2 0.1 3.7e-59 200.8 0.1 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase FliH PF02108.16 ABX12951.1 - 0.031 14.4 0.1 0.082 13.0 0.1 1.7 1 0 0 1 1 1 0 Flagellar assembly protein FliH UDG PF03167.19 ABX12952.1 - 1.6e-41 141.9 0.0 2e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Epimerase_2 PF02350.19 ABX12952.1 - 0.092 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Pur_DNA_glyco PF02245.16 ABX12953.1 - 4.4e-62 208.6 0.1 5.4e-62 208.3 0.1 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) SNARE_assoc PF09335.11 ABX12954.1 - 6.9e-16 58.8 1.2 6.9e-16 58.8 1.2 2.0 2 1 0 2 2 2 1 SNARE associated Golgi protein Glycophorin_A PF01102.18 ABX12954.1 - 0.26 11.6 1.0 0.58 10.4 0.1 1.8 2 0 0 2 2 2 0 Glycophorin A DUF1418 PF07214.12 ABX12954.1 - 0.27 11.1 1.2 2.4 8.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF1454 PF07305.12 ABX12955.1 - 0.038 13.4 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) Med4 PF10018.9 ABX12956.1 - 0.091 12.4 3.1 0.11 12.2 3.1 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 VKG_Carbox PF05090.14 ABX12956.1 - 0.36 9.6 1.4 0.42 9.4 1.4 1.0 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase SpoIIM PF01944.17 ABX12957.1 - 9.5e-06 25.7 10.6 1.3e-05 25.3 10.6 1.1 1 0 0 1 1 1 1 Stage II sporulation protein M Guanylate_cyc PF00211.20 ABX12958.1 - 2.2e-05 24.2 0.0 0.00014 21.5 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Channel_Tsx PF03502.13 ABX12958.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoside-specific channel-forming protein, Tsx ABC_tran PF00005.27 ABX12960.1 - 6.2e-27 94.8 0.0 8.4e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 ABX12960.1 - 3.3e-18 66.0 0.1 5.1e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 ABX12960.1 - 8.8e-06 25.7 1.0 6.3e-05 22.9 0.1 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABX12960.1 - 2.3e-05 23.9 0.3 3.2e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain PRK PF00485.18 ABX12960.1 - 0.015 15.1 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 ABX12960.1 - 0.053 14.1 0.0 0.095 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain KH_5 PF13184.6 ABX12961.1 - 0.039 14.0 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 NusA-like KH domain tRNA-synt_2 PF00152.20 ABX12962.1 - 2.1e-87 293.2 0.0 2.6e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ABX12962.1 - 1.1e-11 44.5 1.2 2e-11 43.7 1.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ABX12962.1 - 0.0017 17.9 0.2 0.17 11.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) NAPRTase PF04095.16 ABX12963.1 - 0.052 13.2 0.1 0.054 13.1 0.1 1.0 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family TRIQK PF15168.6 ABX12964.1 - 0.026 14.4 0.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF2207 PF09972.9 ABX12964.1 - 0.052 12.3 0.1 0.055 12.2 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) E1-E2_ATPase PF00122.20 ABX12964.1 - 0.11 12.0 0.8 0.13 11.8 0.8 1.0 1 0 0 1 1 1 0 E1-E2 ATPase Iso_dh PF00180.20 ABX12965.1 - 1.2e-100 337.1 0.4 1.4e-100 336.9 0.4 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 ABX12965.1 - 0.0009 18.7 0.1 0.0023 17.4 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal phosphate biosynthetic protein PdxA DUF4030 PF13222.6 ABX12965.1 - 0.1 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) HMGL-like PF00682.19 ABX12966.1 - 1.9e-86 289.9 2.1 2.6e-86 289.5 1.2 1.7 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 ABX12966.1 - 6.6e-29 100.5 0.5 1.3e-28 99.6 0.5 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain AP_endonuc_2 PF01261.24 ABX12966.1 - 0.084 12.3 0.2 0.58 9.6 0.1 2.4 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel ALS_ss_C PF10369.9 ABX12967.1 - 1.9e-23 82.5 0.7 3.8e-21 75.1 0.0 2.6 2 1 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.25 ABX12967.1 - 1.2e-13 50.6 0.1 2.4e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 ABX12967.1 - 3.6e-13 49.2 0.0 6.6e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 ABX12967.1 - 0.00053 20.5 0.1 0.0013 19.3 0.1 1.6 1 0 0 1 1 1 1 ACT domain Acylphosphatase PF00708.18 ABX12967.1 - 0.049 14.0 0.1 0.91 10.0 0.0 2.2 2 0 0 2 2 2 0 Acylphosphatase SLS PF14611.6 ABX12967.1 - 0.076 12.8 0.2 0.086 12.7 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator TPP_enzyme_N PF02776.18 ABX12968.1 - 8.3e-61 204.6 0.2 1.1e-57 194.4 0.2 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABX12968.1 - 1.1e-47 161.2 0.2 2.7e-47 159.9 0.2 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ABX12968.1 - 5.1e-47 159.5 1.2 2.4e-46 157.3 0.1 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M_2 PF16582.5 ABX12968.1 - 0.0061 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Middle domain of thiamine pyrophosphate fn3 PF00041.21 ABX12969.1 - 0 2772.8 376.5 2.8e-15 56.4 0.8 81.3 81 1 0 81 81 81 77 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 ABX12969.1 - 3.9e-106 347.9 325.5 0.00038 21.0 0.9 72.9 74 1 0 74 74 74 41 Purple acid Phosphatase, N-terminal domain DUF4998 PF16389.5 ABX12969.1 - 1.9e-70 236.5 3.1 0.034 13.7 0.0 35.6 28 8 7 35 35 35 16 Domain of unknown function Tissue_fac PF01108.17 ABX12969.1 - 4.5e-44 148.7 4.1 0.17 11.7 0.0 34.2 40 1 1 41 41 41 5 Tissue factor DUF2369 PF10179.9 ABX12969.1 - 5.9e-31 106.7 38.0 4.6 7.7 0.0 33.8 44 0 0 44 44 41 5 Uncharacterised conserved protein (DUF2369) DUF4959 PF16323.5 ABX12969.1 - 4.8e-26 91.2 100.8 0.062 13.6 0.1 35.5 32 11 11 43 43 42 9 Domain of unknown function (DUF4959) FlgD_ig PF13860.6 ABX12969.1 - 3.9e-20 71.5 111.6 0.016 15.1 0.6 20.5 20 0 0 20 20 20 12 FlgD Ig-like domain SusE PF14292.6 ABX12969.1 - 1.4e-15 57.4 459.9 0.0068 16.6 1.4 64.2 40 14 24 69 69 68 25 SusE outer membrane protein F5_F8_type_C PF00754.25 ABX12969.1 - 1.7e-08 34.7 144.6 0.23 11.6 0.5 35.3 39 0 0 39 39 39 4 F5/8 type C domain Interfer-bind PF09294.10 ABX12969.1 - 1.5e-06 28.5 0.0 50 4.3 0.0 13.5 18 0 0 18 18 17 0 Interferon-alpha/beta receptor, fibronectin type III Phage_head_chap PF11113.8 ABX12969.1 - 0.017 15.2 1.1 57 3.9 0.0 7.2 7 0 0 7 7 5 0 Head assembly gene product Atg14 PF10186.9 ABX12970.1 - 0.0026 16.9 4.7 0.0038 16.4 4.7 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TRAF_BIRC3_bd PF16673.5 ABX12970.1 - 0.0028 17.4 3.9 0.0028 17.4 3.9 2.5 1 1 1 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain Leu_zip PF15294.6 ABX12970.1 - 0.0031 17.1 4.1 0.0052 16.4 4.1 1.4 1 0 0 1 1 1 1 Leucine zipper ERM PF00769.19 ABX12970.1 - 0.0086 15.9 9.6 0.014 15.3 9.6 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family FPP PF05911.11 ABX12970.1 - 0.012 13.9 8.0 0.016 13.5 8.0 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Exonuc_VII_L PF02601.15 ABX12970.1 - 0.014 15.0 1.8 0.019 14.5 1.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FTA4 PF13093.6 ABX12970.1 - 0.024 14.6 2.2 0.04 13.8 2.2 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HAUS6_N PF14661.6 ABX12970.1 - 0.027 14.0 2.4 0.041 13.4 2.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4795 PF16043.5 ABX12970.1 - 0.03 13.9 1.4 0.03 13.9 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) AAA_15 PF13175.6 ABX12970.1 - 0.03 14.0 1.3 0.046 13.4 1.3 1.3 1 0 0 1 1 1 0 AAA ATPase domain Tektin PF03148.14 ABX12970.1 - 0.047 12.4 8.8 0.092 11.5 8.8 1.4 1 0 0 1 1 1 0 Tektin family Fez1 PF06818.15 ABX12970.1 - 0.059 13.8 8.0 0.088 13.3 8.0 1.2 1 0 0 1 1 1 0 Fez1 Tropomyosin_1 PF12718.7 ABX12970.1 - 0.066 13.4 19.0 24 5.1 19.0 2.2 1 1 0 1 1 1 0 Tropomyosin like Spc7 PF08317.11 ABX12970.1 - 0.078 11.9 15.5 0.12 11.3 15.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fzo_mitofusin PF04799.13 ABX12970.1 - 0.18 11.3 6.7 0.23 11.0 4.0 2.1 2 0 0 2 2 2 0 fzo-like conserved region FlxA PF14282.6 ABX12970.1 - 0.3 11.1 19.7 1.1 9.2 18.9 2.1 1 1 0 1 1 1 0 FlxA-like protein KASH_CCD PF14662.6 ABX12970.1 - 0.31 10.9 15.0 0.46 10.3 15.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HOOK PF05622.12 ABX12970.1 - 0.31 9.1 14.1 0.44 8.6 14.1 1.1 1 0 0 1 1 1 0 HOOK protein V_ATPase_I PF01496.19 ABX12970.1 - 0.34 8.8 2.3 0.44 8.4 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 ABX12970.1 - 0.35 9.3 1.8 0.47 8.9 1.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GAS PF13851.6 ABX12970.1 - 0.36 10.2 12.1 0.71 9.2 12.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Geminin PF07412.12 ABX12970.1 - 0.36 10.5 8.1 0.63 9.8 8.1 1.3 1 0 0 1 1 1 0 Geminin DUF3450 PF11932.8 ABX12970.1 - 0.45 9.8 18.6 0.33 10.2 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 ABX12970.1 - 0.5 9.6 4.7 0.85 8.8 4.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein Frigida PF07899.11 ABX12970.1 - 0.54 9.5 6.5 0.96 8.7 6.5 1.4 1 0 0 1 1 1 0 Frigida-like protein Mod_r PF07200.13 ABX12970.1 - 0.58 10.3 13.7 1 9.5 13.7 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FAM76 PF16046.5 ABX12970.1 - 0.63 9.3 3.7 0.9 8.8 3.7 1.1 1 0 0 1 1 1 0 FAM76 protein ABC_tran_CTD PF16326.5 ABX12970.1 - 0.87 9.9 23.1 0.3 11.4 1.0 3.2 2 1 0 2 2 2 0 ABC transporter C-terminal domain Golgin_A5 PF09787.9 ABX12970.1 - 1.1 8.6 15.2 1.6 8.1 15.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 AAA_13 PF13166.6 ABX12970.1 - 1.2 7.6 10.3 1.8 7.1 10.3 1.1 1 0 0 1 1 1 0 AAA domain Nup54 PF13874.6 ABX12970.1 - 1.3 9.2 9.4 1.5 8.9 8.7 1.4 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 TolA_bind_tri PF16331.5 ABX12970.1 - 1.7 8.8 13.9 0.89 9.7 3.0 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF724 PF05266.14 ABX12970.1 - 1.7 8.4 13.6 0.95 9.3 9.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DASH_Dad3 PF08656.10 ABX12970.1 - 2 8.5 5.2 11 6.2 1.1 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad3 Fib_alpha PF08702.10 ABX12970.1 - 2.5 8.3 9.8 6.1 7.0 9.8 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Tropomyosin PF00261.20 ABX12970.1 - 3 7.2 18.8 4.3 6.6 18.8 1.2 1 0 0 1 1 1 0 Tropomyosin Laminin_II PF06009.12 ABX12970.1 - 3 7.9 10.6 7.2 6.6 10.0 1.8 1 1 0 1 1 1 0 Laminin Domain II PCRF PF03462.18 ABX12970.1 - 3.2 7.6 10.3 5.3 6.9 10.3 1.3 1 0 0 1 1 1 0 PCRF domain ACCA PF03255.14 ABX12970.1 - 4 7.3 9.9 3.6 7.5 2.4 2.7 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Seryl_tRNA_N PF02403.22 ABX12970.1 - 4.3 7.6 15.3 2.4 8.4 3.7 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PspA_IM30 PF04012.12 ABX12970.1 - 4.7 6.7 19.2 4.4e+02 0.3 18.8 2.7 1 1 0 1 1 1 0 PspA/IM30 family Swi5 PF07061.11 ABX12970.1 - 7.1 6.8 13.0 0.52 10.4 1.9 2.7 2 1 0 2 2 2 0 Swi5 DUF5082 PF16888.5 ABX12970.1 - 8.7 6.6 16.8 13 6.1 0.4 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) BLOC1_2 PF10046.9 ABX12970.1 - 8.8 6.7 13.6 14 6.1 3.8 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 ABX12971.1 - 0.004 16.1 32.2 0.004 16.1 32.2 9.6 2 2 9 11 11 11 7 Spc7 kinetochore protein HAMP PF00672.25 ABX12972.1 - 3.5e-10 40.1 0.0 2.1e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 HAMP domain DUF4844 PF16133.5 ABX12972.1 - 0.039 14.5 3.3 0.1 13.1 1.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4844) SnoaL_3 PF13474.6 ABX12973.1 - 2.6e-09 37.4 0.0 3.3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABX12973.1 - 8.8e-06 26.1 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.10 ABX12973.1 - 4.3e-05 23.6 0.0 8.6e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain DeoC PF01791.9 ABX12974.1 - 1.4e-21 77.2 0.0 1.8e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase DUF5563 PF17718.1 ABX12974.1 - 0.0036 16.9 2.5 0.0036 16.9 2.5 1.7 1 1 1 2 2 2 1 Family of unknown function (DUF5563) Gti1_Pac2 PF09729.9 ABX12974.1 - 0.66 10.0 12.1 0.94 9.5 12.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family ADH_N PF08240.12 ABX12975.1 - 3.4e-23 81.6 3.0 6.2e-23 80.8 3.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABX12975.1 - 1.2e-19 70.6 0.1 1.7e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABX12975.1 - 7.9e-14 51.7 0.1 1.1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ABX12975.1 - 7.5e-07 30.3 0.1 1.3e-06 29.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GARS_N PF02844.15 ABX12975.1 - 0.13 13.1 0.0 0.27 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain UPF0524 PF15823.5 ABX12975.1 - 0.23 10.8 2.6 0.37 10.1 2.6 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 ATP-synt_F PF01990.17 ABX12976.1 - 2.4e-13 50.2 0.1 2.6e-13 50.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Trp_syntA PF00290.20 ABX12976.1 - 0.003 16.5 0.0 0.003 16.5 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain LUD_dom PF02589.15 ABX12976.1 - 0.071 12.8 0.0 0.072 12.8 0.0 1.1 1 0 0 1 1 1 0 LUD domain SWIM PF04434.17 ABX12979.1 - 0.0007 19.2 0.2 0.0011 18.6 0.2 1.3 1 0 0 1 1 1 1 SWIM zinc finger Metallophos PF00149.28 ABX12980.1 - 3.2e-09 37.6 0.2 4.8e-08 33.8 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ABX12980.1 - 4e-06 27.1 0.0 6.3e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DNA_pol_E_B PF04042.16 ABX12980.1 - 0.021 14.2 0.1 0.078 12.3 0.1 2.0 1 1 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Epimerase_2 PF02350.19 ABX12980.1 - 0.038 12.9 0.0 0.068 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase CPSase_L_D2 PF02786.17 ABX12981.1 - 4.5e-101 336.7 0.1 1.5e-73 246.7 0.2 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 ABX12981.1 - 2.3e-35 121.6 0.0 5.8e-35 120.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 ABX12981.1 - 3.6e-20 72.2 0.4 3.9e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ABX12981.1 - 8.9e-17 61.3 1.2 4.2e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 ABX12981.1 - 6.3e-15 55.1 0.1 3e-14 53.0 0.1 2.3 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.6 ABX12981.1 - 4.7e-12 45.8 0.0 2.9e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 ABX12981.1 - 2.5e-11 43.7 1.3 3.3e-05 23.7 0.1 2.8 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 ABX12981.1 - 2.6e-06 27.6 1.4 0.0052 16.9 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_4 PF13535.6 ABX12981.1 - 4.1e-06 26.5 3.0 0.014 15.0 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_2 PF08442.10 ABX12981.1 - 0.0012 18.4 0.2 0.0069 16.0 0.2 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.6 ABX12981.1 - 0.0043 16.5 0.1 0.088 12.2 0.1 2.7 2 1 1 3 3 3 1 ATP-grasp domain ZnuA PF01297.17 ABX12981.1 - 0.037 13.4 0.1 0.14 11.5 0.1 1.9 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic TrkA_N PF02254.18 ABX12981.1 - 0.039 14.2 0.0 0.38 11.0 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 ABX12981.1 - 3.3 8.3 7.2 0.92 10.1 0.3 3.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase CPSase_sm_chain PF00988.22 ABX12982.1 - 1.2e-49 167.3 0.0 4.7e-49 165.5 0.0 1.9 2 1 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ABX12982.1 - 9.1e-46 156.0 0.0 1.6e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ABX12982.1 - 1.7e-07 31.2 0.5 5.3e-05 23.1 0.3 2.6 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 ABX12982.1 - 0.07 12.9 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 DJ-1/PfpI family AAA PF00004.29 ABX12984.1 - 2e-37 128.6 0.0 5e-37 127.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 ABX12984.1 - 1.7e-10 40.8 0.7 3.8e-10 39.7 0.7 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_2 PF07724.14 ABX12984.1 - 2.2e-07 31.1 0.1 5.8e-07 29.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 ABX12984.1 - 3.2e-07 30.2 0.3 6e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 ABX12984.1 - 9.4e-06 26.1 0.0 0.0065 16.9 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_lid_3 PF17862.1 ABX12984.1 - 2e-05 24.3 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 ABX12984.1 - 3.6e-05 24.1 0.0 0.0024 18.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ABX12984.1 - 0.00011 22.0 0.0 0.00035 20.4 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 ABX12984.1 - 0.00017 21.4 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ABX12984.1 - 0.0002 21.5 0.1 0.042 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ABX12984.1 - 0.00097 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 ABX12984.1 - 0.0022 18.0 0.2 0.018 15.1 0.0 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ABX12984.1 - 0.0052 16.2 0.1 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 ABX12984.1 - 0.0058 16.6 0.0 2 8.2 0.0 2.5 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea TIP49 PF06068.13 ABX12984.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 ABX12984.1 - 0.011 15.3 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ABX12984.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF5113 PF17140.4 ABX12984.1 - 0.022 14.5 1.1 0.53 10.1 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) AAA_11 PF13086.6 ABX12984.1 - 0.023 14.5 0.2 0.12 12.1 0.0 2.1 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 ABX12984.1 - 0.024 13.9 0.0 0.066 12.5 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 ABX12984.1 - 0.026 14.9 0.2 0.45 10.9 0.0 2.6 2 1 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 ABX12984.1 - 0.027 14.5 0.0 0.08 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 ABX12984.1 - 0.069 12.4 0.0 1.1 8.4 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain ATPase PF06745.13 ABX12984.1 - 0.071 12.4 0.1 2 7.7 0.1 2.2 1 1 1 2 2 2 0 KaiC ABC_tran PF00005.27 ABX12984.1 - 0.12 12.9 0.2 3.2 8.3 0.0 2.8 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.17 ABX12984.1 - 0.13 11.3 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 ABX12984.1 - 0.16 12.3 0.5 4 7.8 0.3 2.8 2 1 1 3 3 3 0 AAA domain NACHT PF05729.12 ABX12984.1 - 0.16 11.9 0.0 0.67 9.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 ABX12984.1 - 0.17 11.3 0.3 0.36 10.2 0.3 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 ABX12984.1 - 0.18 11.5 0.1 0.69 9.6 0.1 2.0 1 1 1 2 2 2 0 AAA domain HHH_8 PF14716.6 ABX12985.1 - 0.0081 16.5 0.6 0.08 13.3 0.1 2.6 1 1 2 3 3 3 1 Helix-hairpin-helix domain DUF948 PF06103.11 ABX12985.1 - 0.014 15.6 0.1 0.071 13.4 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4909 PF16253.5 ABX12985.1 - 0.023 14.5 2.6 0.52 10.1 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4909) DNA_topoisoIV PF00521.20 ABX12986.1 - 0.011 14.6 0.7 0.015 14.2 0.7 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A TrmB PF01978.19 ABX12987.1 - 5.1e-18 64.7 0.2 3.7e-16 58.8 0.1 2.4 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 ABX12987.1 - 0.037 14.0 1.4 0.13 12.3 0.0 2.5 3 0 0 3 3 3 0 HTH domain YjgF_endoribonc PF14588.6 ABX12988.1 - 6.9e-34 117.1 0.0 7.6e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 ABX12988.1 - 8.7e-20 70.9 0.0 1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP SDF PF00375.18 ABX12989.1 - 1.4e-112 376.6 45.5 1.6e-112 376.4 45.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Putative_PNPOx PF01243.20 ABX12990.1 - 1.2e-07 31.8 0.0 1.7e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 ABX12990.1 - 0.023 14.3 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like TbpB_B_D PF01298.18 ABX12990.1 - 0.034 14.5 0.2 0.053 13.9 0.2 1.2 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Pyridox_ox_2 PF12900.7 ABX12990.1 - 0.087 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DoxX_2 PF13564.6 ABX12991.1 - 0.081 13.0 6.9 0.12 12.5 0.2 2.2 2 0 0 2 2 2 0 DoxX-like family COX14 PF14880.6 ABX12991.1 - 0.67 9.8 3.8 0.26 11.2 0.5 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF3796 PF12676.7 ABX12991.1 - 6.7 7.2 9.1 17 5.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) DUF3179 PF11376.8 ABX12992.1 - 2.5e-105 351.9 0.0 2.9e-105 351.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3179) DoxX PF07681.12 ABX12993.1 - 4e-11 43.3 1.5 4e-11 43.3 1.5 1.5 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 ABX12993.1 - 1.1e-05 25.4 0.9 1.3e-05 25.2 0.9 1.2 1 0 0 1 1 1 1 TQO small subunit DoxD DoxX_2 PF13564.6 ABX12993.1 - 0.0012 18.9 3.6 0.0021 18.1 3.5 1.6 1 1 0 1 1 1 1 DoxX-like family DuoxA PF10204.9 ABX12993.1 - 0.007 15.4 0.3 0.0082 15.2 0.3 1.2 1 0 0 1 1 1 1 Dual oxidase maturation factor Phage_holin_3_6 PF07332.11 ABX12993.1 - 0.44 10.6 4.8 0.66 10.0 4.8 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DHHA1 PF02272.19 ABX12994.1 - 3.6e-16 59.8 0.6 3.6e-16 59.8 0.6 2.5 2 0 0 2 2 2 1 DHHA1 domain DHH PF01368.20 ABX12994.1 - 0.00046 20.4 3.4 0.00078 19.7 2.6 1.8 1 1 1 2 2 2 1 DHH family ssDNA-exonuc_C PF10141.9 ABX12994.1 - 0.0074 16.0 0.6 0.014 15.1 0.6 1.4 1 0 0 1 1 1 1 Single-strand DNA-specific exonuclease, C terminal domain Utp14 PF04615.13 ABX12994.1 - 0.022 13.4 6.0 0.032 12.8 6.0 1.1 1 0 0 1 1 1 0 Utp14 protein Citrate_synt PF00285.21 ABX12995.1 - 3.3e-132 441.0 0.0 3.7e-132 440.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF1940 PF09155.10 ABX12995.1 - 0.025 14.7 0.2 0.12 12.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1940) UPF0146 PF03686.13 ABX12995.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Copper-bind PF00127.20 ABX12998.1 - 7.2e-10 39.2 1.3 1.3e-09 38.4 0.2 2.0 2 1 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX12998.1 - 1.6e-06 28.2 0.0 1.3e-05 25.3 0.0 2.4 3 0 0 3 3 3 1 Cupredoxin-like domain UvrC_HhH_N PF08459.11 ABX12999.1 - 1.7e-48 164.5 0.0 4.9e-48 162.9 0.0 1.8 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.24 ABX12999.1 - 1.8e-11 44.2 2.1 3.9e-11 43.1 0.6 2.4 2 0 0 2 2 2 1 GIY-YIG catalytic domain UVR PF02151.19 ABX12999.1 - 3.3e-09 36.2 0.7 7.9e-09 35.0 0.7 1.7 1 0 0 1 1 1 1 UvrB/uvrC motif LIN52 PF10044.9 ABX12999.1 - 0.0085 16.8 1.4 0.1 13.3 0.6 2.6 3 0 0 3 3 3 1 Retinal tissue protein Comm PF15957.5 ABX12999.1 - 0.17 12.2 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Commissureless UvrA_inter PF17760.1 ABX13000.1 - 7.8e-36 122.5 0.7 1.8e-35 121.3 0.3 1.9 2 0 0 2 2 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 ABX13000.1 - 2.7e-35 121.0 0.1 1.5e-32 112.2 0.0 3.7 4 0 0 4 4 3 1 UvrA DNA-binding domain ABC_tran PF00005.27 ABX13000.1 - 6.3e-23 81.8 0.4 2.8e-09 37.6 0.1 4.5 3 1 0 3 3 3 3 ABC transporter SMC_N PF02463.19 ABX13000.1 - 7.5e-11 41.9 0.7 0.045 13.2 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ABX13000.1 - 4.6e-08 33.2 4.4 0.066 13.0 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABX13000.1 - 6.1e-08 32.3 0.2 0.0083 15.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ABX13000.1 - 1e-07 32.5 0.0 0.045 14.1 0.0 3.6 4 0 0 4 4 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 ABX13000.1 - 8.3e-07 29.1 0.2 0.011 15.6 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase NB-ARC PF00931.22 ABX13000.1 - 1.2e-05 24.7 0.0 0.092 11.9 0.0 3.8 4 0 0 4 4 4 1 NB-ARC domain AAA_23 PF13476.6 ABX13000.1 - 1.9e-05 25.3 5.3 0.0032 18.0 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 ABX13000.1 - 2.1e-05 24.8 1.0 0.22 11.8 0.0 4.3 5 0 0 5 5 4 2 AAA domain AAA_14 PF13173.6 ABX13000.1 - 3.3e-05 23.9 0.1 0.63 10.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 ABX13000.1 - 4.1e-05 23.3 0.6 0.28 10.7 0.0 4.3 5 1 0 5 5 4 1 AAA domain AAA_33 PF13671.6 ABX13000.1 - 6e-05 23.2 0.1 0.3 11.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 ABX13000.1 - 0.00019 21.3 8.5 0.63 9.7 0.0 4.6 5 0 0 5 5 5 1 AAA ATPase domain AAA_18 PF13238.6 ABX13000.1 - 0.00026 21.5 0.0 1.3 9.6 0.0 3.3 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 ABX13000.1 - 0.00027 21.0 0.5 0.47 10.3 0.0 3.5 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 ABX13000.1 - 0.0004 20.3 0.0 0.4 10.6 0.0 2.7 3 0 0 3 3 2 1 NACHT domain DnaJ_CXXCXGXG PF00684.19 ABX13000.1 - 0.00049 20.4 7.6 0.02 15.2 0.3 4.0 3 1 0 3 3 3 1 DnaJ central domain APS_kinase PF01583.20 ABX13000.1 - 0.00055 19.9 0.1 1.6 8.6 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase Viral_helicase1 PF01443.18 ABX13000.1 - 0.00085 19.1 0.1 0.12 12.1 0.1 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase cobW PF02492.19 ABX13000.1 - 0.00086 18.9 0.2 0.23 11.1 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ABX13000.1 - 0.0015 18.6 0.5 0.13 12.4 0.1 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase ATPase PF06745.13 ABX13000.1 - 0.0016 17.8 0.0 1.4 8.2 0.0 2.9 2 0 0 2 2 2 1 KaiC RNA_helicase PF00910.22 ABX13000.1 - 0.006 16.9 0.0 1.8 9.0 0.0 3.0 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 ABX13000.1 - 0.0064 16.4 0.2 1.1 9.1 0.0 3.7 3 0 0 3 3 3 1 NTPase T2SSE PF00437.20 ABX13000.1 - 0.0065 15.6 0.1 2.5 7.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 ABX13000.1 - 0.0071 15.9 0.1 0.99 8.9 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_24 PF13479.6 ABX13000.1 - 0.0079 15.9 3.3 18 5.0 0.1 4.4 4 0 0 4 4 4 0 AAA domain DUF2075 PF09848.9 ABX13000.1 - 0.0092 15.3 0.1 3.9 6.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 ABX13000.1 - 0.02 13.8 0.0 0.52 9.3 0.0 2.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ABX13000.1 - 0.029 14.1 0.1 8.2 6.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 ABX13000.1 - 0.035 14.4 0.0 11 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 ABX13000.1 - 0.035 14.0 0.1 2.2 8.2 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 ABX13000.1 - 0.037 13.3 0.0 3.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin RACo_linker PF17650.1 ABX13000.1 - 0.043 13.7 0.2 5.7 6.9 0.0 3.5 4 0 0 4 4 3 0 RACo linker region dNK PF01712.19 ABX13000.1 - 0.067 13.0 0.1 4.2 7.2 0.1 2.7 2 0 0 2 2 2 0 Deoxynucleoside kinase PRK PF00485.18 ABX13000.1 - 0.071 12.8 0.4 1.3 8.7 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.18 ABX13000.1 - 0.15 11.4 0.1 7.8 5.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 ABX13000.1 - 1.1 9.3 4.0 14 5.7 0.0 3.7 4 0 0 4 4 4 0 Helicase HerA, central domain zinc_ribbon_2 PF13240.6 ABX13000.1 - 1.8 8.4 9.4 0.94 9.3 0.2 2.9 3 0 0 3 3 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 ABX13000.1 - 6 6.4 8.6 0.88 9.1 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain UvrB_inter PF17757.1 ABX13001.1 - 1.5e-30 105.2 0.6 6.7e-30 103.1 0.2 2.3 2 0 0 2 2 2 1 UvrB interaction domain UvrB PF12344.8 ABX13001.1 - 4.1e-21 74.6 6.0 1e-20 73.3 6.0 1.8 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 ABX13001.1 - 5.4e-19 68.6 1.0 2.2e-18 66.6 0.2 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UVR PF02151.19 ABX13001.1 - 1.7e-09 37.1 4.1 1.7e-09 37.1 4.1 3.3 3 0 0 3 3 3 1 UvrB/uvrC motif ResIII PF04851.15 ABX13001.1 - 2.6e-07 30.8 0.2 2.6e-07 30.8 0.2 3.1 2 1 2 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ABX13001.1 - 7.8e-07 29.0 0.4 0.00036 20.3 0.1 3.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 ABX13001.1 - 0.0011 18.7 0.0 0.023 14.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain UB2H PF14814.6 ABX13001.1 - 0.0055 16.7 0.0 0.024 14.7 0.0 2.1 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain Met_synt_B12 PF02965.17 ABX13001.1 - 0.0064 16.0 0.6 0.11 12.0 0.1 2.8 3 0 0 3 3 3 1 Vitamin B12 dependent methionine synthase, activation domain Rhomboid_N PF12122.8 ABX13001.1 - 0.037 14.2 0.1 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease Microtub_bd PF16796.5 ABX13001.1 - 0.055 13.4 1.2 3.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Microtubule binding Tup_N PF08581.10 ABX13001.1 - 0.17 12.2 9.4 0.5 10.7 0.1 3.6 3 0 0 3 3 3 0 Tup N-terminal AAA_19 PF13245.6 ABX13001.1 - 0.84 10.0 5.0 15 5.9 0.6 2.9 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.6 ABX13001.1 - 1.1 9.6 3.6 2.7 8.3 0.0 3.2 4 1 0 4 4 3 0 AAA domain Pyridox_ox_2 PF12900.7 ABX13002.1 - 1.3e-18 67.4 0.0 1.6e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 ABX13002.1 - 1.4e-11 44.4 0.0 2.9e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RNA_pol_Rpc34 PF05158.12 ABX13003.1 - 0.015 14.7 0.0 0.015 14.7 0.0 1.4 2 0 0 2 2 2 0 RNA polymerase Rpc34 subunit Adeno_E4 PF05385.11 ABX13003.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.9 2 0 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein Bac_luciferase PF00296.20 ABX13005.1 - 3.1e-54 184.5 0.0 4e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Fe-ADH PF00465.19 ABX13006.1 - 1.3e-48 165.7 0.0 2.2e-48 164.9 0.0 1.3 1 1 1 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ABX13006.1 - 3.2e-16 59.8 0.0 4.3e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 ABX13006.1 - 8e-06 25.2 0.0 0.0025 17.0 0.0 2.1 2 0 0 2 2 2 2 3-dehydroquinate synthase DUF4147 PF13660.6 ABX13007.1 - 3.4e-69 232.9 0.0 5.3e-69 232.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 ABX13007.1 - 1.6e-29 102.3 0.7 1.8e-28 98.9 0.5 2.2 2 0 0 2 2 2 1 MOFRL family Peptidase_C13 PF01650.18 ABX13007.1 - 0.00014 21.5 1.7 0.0018 17.8 0.2 3.0 1 1 1 2 2 2 1 Peptidase C13 family THP2 PF09432.10 ABX13007.1 - 0.032 14.3 1.1 1.9 8.5 1.5 2.5 2 0 0 2 2 2 0 Tho complex subunit THP2 Aconitase_B_N PF11791.8 ABX13007.1 - 0.063 13.3 0.2 0.21 11.6 0.2 1.9 2 0 0 2 2 2 0 Aconitate B N-terminal domain DUF1768 PF08719.11 ABX13008.1 - 0.082 13.1 1.2 0.091 13.0 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) RMMBL PF07521.12 ABX13009.1 - 5.2e-05 23.1 0.0 0.00018 21.4 0.0 1.9 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain DRMBL PF07522.14 ABX13009.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase Formyl_trans_N PF00551.19 ABX13010.1 - 1.3e-46 158.7 0.0 1.4e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Cupin_2 PF07883.11 ABX13011.1 - 4.7e-11 42.2 0.0 1e-10 41.1 0.0 1.5 2 0 0 2 2 2 1 Cupin domain CENP-C_C PF11699.8 ABX13011.1 - 7.6e-07 29.3 0.1 9.6e-07 28.9 0.1 1.1 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.19 ABX13011.1 - 3.7e-05 23.7 0.0 4.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain DMSP_lyase PF16867.5 ABX13011.1 - 0.00019 21.1 0.0 0.00024 20.8 0.0 1.1 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase ARD PF03079.14 ABX13011.1 - 0.013 15.7 0.5 0.019 15.2 0.5 1.5 1 1 0 1 1 1 0 ARD/ARD' family Pirin_C PF05726.13 ABX13011.1 - 0.017 15.5 0.0 0.024 15.0 0.0 1.1 1 0 0 1 1 1 0 Pirin C-terminal cupin domain Ectoine_synth PF06339.12 ABX13011.1 - 0.02 15.1 0.0 0.025 14.8 0.0 1.1 1 0 0 1 1 1 0 Ectoine synthase ABM PF03992.16 ABX13012.1 - 6.1e-08 32.7 0.0 7.3e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SOR PF07682.11 ABX13012.1 - 0.034 13.0 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Sulphur oxygenase reductase THF_DHG_CYH_C PF02882.19 ABX13013.1 - 4.6e-60 201.5 0.6 7e-60 201.0 0.6 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 ABX13013.1 - 2.8e-40 137.2 0.6 4.4e-40 136.6 0.6 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Hydrolase PF00702.26 ABX13013.1 - 0.00067 20.0 0.2 0.0016 18.8 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sacchrp_dh_NADP PF03435.18 ABX13013.1 - 0.0024 18.1 0.6 0.031 14.5 0.1 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 ABX13013.1 - 0.0027 17.0 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Exog_C PF18026.1 ABX13013.1 - 0.016 15.3 0.0 0.84 9.7 0.0 2.3 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain OCD_Mu_crystall PF02423.15 ABX13013.1 - 0.016 14.1 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Semialdhyde_dh PF01118.24 ABX13013.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain LacI PF00356.21 ABX13013.1 - 0.13 12.0 0.9 3 7.7 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family 5-FTHF_cyc-lig PF01812.20 ABX13014.1 - 2.9e-40 138.1 0.0 3.3e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family GARS_A PF01071.19 ABX13015.1 - 2.8e-80 268.7 0.2 3.7e-80 268.3 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 ABX13015.1 - 2.8e-33 114.6 0.0 8.1e-33 113.1 0.0 1.8 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 ABX13015.1 - 2.7e-29 101.3 0.0 9.8e-29 99.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 ABX13015.1 - 7.4e-08 32.2 0.0 1.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ABX13015.1 - 3e-06 27.4 0.0 4.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 ABX13015.1 - 4.5e-06 26.3 0.0 8.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.10 ABX13015.1 - 5.2e-06 26.2 0.0 9.6e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ABX13015.1 - 0.00012 21.7 0.1 0.00019 21.0 0.1 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 ABX13015.1 - 0.00022 20.9 0.0 0.00047 19.8 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 ABX13015.1 - 0.0052 16.1 0.1 0.032 13.5 0.1 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 ABX13015.1 - 0.018 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 ABX13015.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Phage_TAC_9 PF10876.8 ABX13015.1 - 0.12 12.4 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 Phage tail assemb.y chaperone protein, TAC tRNA-synt_1 PF00133.22 ABX13016.1 - 1.4e-140 469.4 1.0 2.1e-140 468.9 1.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ABX13016.1 - 5.4e-31 107.6 0.2 1.4e-30 106.3 0.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ABX13016.1 - 1.8e-23 82.9 0.0 2.6e-10 39.6 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ABX13016.1 - 4.6e-05 22.9 0.0 0.0017 17.8 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 ABX13016.1 - 0.00019 20.5 0.0 0.00052 19.0 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (K) Zn-ribbon_8 PF09723.10 ABX13016.1 - 1.1 9.4 2.7 6.9 6.9 0.0 3.0 3 0 0 3 3 3 0 Zinc ribbon domain Ferritin PF00210.24 ABX13017.1 - 5.6e-23 81.5 0.0 7.8e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain PH_18 PF18469.1 ABX13018.1 - 0.013 15.5 0.2 0.041 13.9 0.2 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain tRNA_bind PF01588.20 ABX13018.1 - 0.068 13.3 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative tRNA binding domain ATP-grasp_2 PF08442.10 ABX13019.1 - 1.7e-44 151.9 3.0 2.9e-44 151.1 3.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 ABX13019.1 - 1.4e-14 54.2 0.3 3e-14 53.1 0.3 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 ABX13019.1 - 9.9e-14 51.3 0.2 3.9e-13 49.4 0.2 1.9 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 ABX13019.1 - 5.5e-06 26.0 0.0 9.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 ABX13019.1 - 0.016 14.7 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp domain Bac_DNA_binding PF00216.21 ABX13019.1 - 0.21 11.8 1.4 0.35 11.1 0.3 1.9 2 0 0 2 2 2 0 Bacterial DNA-binding protein CoA_binding PF02629.19 ABX13020.1 - 2.4e-22 79.4 1.1 4.9e-22 78.4 0.6 1.8 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 ABX13020.1 - 8.7e-08 32.1 0.1 1.6e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding_2 PF13380.6 ABX13020.1 - 6e-06 26.7 0.0 9.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 ABX13020.1 - 7.4e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.22 ABX13020.1 - 0.0014 19.5 0.1 0.0024 18.7 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold zinc_ribbon_2 PF13240.6 ABX13021.1 - 0.0007 19.2 3.7 0.001 18.7 3.7 1.2 1 0 0 1 1 1 1 zinc-ribbon domain Ribosomal_L40e PF01020.17 ABX13021.1 - 0.0015 18.4 4.1 0.0035 17.2 3.9 1.7 1 1 1 2 2 2 1 Ribosomal L40e family DZR PF12773.7 ABX13021.1 - 0.0026 17.7 0.6 0.0029 17.6 0.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 ABX13021.1 - 0.0085 15.5 1.6 0.012 15.0 1.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-CCHC PF00098.23 ABX13021.1 - 0.99 9.6 6.2 1 9.6 0.6 2.2 2 0 0 2 2 2 0 Zinc knuckle Ectatomin PF06457.11 ABX13023.1 - 0.029 14.3 0.9 0.066 13.1 0.9 1.6 1 0 0 1 1 1 0 Ectatomin ZnuA PF01297.17 ABX13024.1 - 3.9e-73 246.0 0.2 4.4e-73 245.9 0.2 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic DUF3453 PF11935.8 ABX13024.1 - 0.037 13.7 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Cupredoxin_1 PF13473.6 ABX13025.1 - 0.0038 17.3 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 ABX13025.1 - 0.022 15.2 0.8 0.084 13.3 0.0 2.2 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family Zip PF02535.22 ABX13026.1 - 0.0035 16.6 18.0 0.0035 16.6 18.0 2.9 1 1 1 2 2 2 1 ZIP Zinc transporter PIRT PF15099.6 ABX13026.1 - 0.033 13.8 7.5 0.062 12.9 0.1 2.8 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family MotA_ExbB PF01618.16 ABX13026.1 - 0.055 13.2 2.1 0.23 11.2 0.0 2.9 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family DUF2070 PF09843.9 ABX13026.1 - 0.9 7.8 15.8 0.025 12.9 7.4 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Cu-oxidase_3 PF07732.15 ABX13027.1 - 2.6e-23 82.3 5.5 9.1e-20 70.8 0.6 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ABX13027.1 - 9.2e-21 74.0 6.9 1.3e-09 38.0 0.3 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 ABX13027.1 - 0.14 12.3 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Cupredoxin-like domain Fe_dep_repress PF01325.19 ABX13028.1 - 9.9e-22 76.9 0.1 1.6e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.15 ABX13028.1 - 2e-14 53.4 0.0 3.9e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain HTH_Crp_2 PF13545.6 ABX13028.1 - 3.3e-05 23.8 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 ABX13028.1 - 8e-05 22.5 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 MarR family DUF4423 PF14394.6 ABX13028.1 - 0.00023 20.9 0.1 0.0005 19.8 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) MarR PF01047.22 ABX13028.1 - 0.0019 18.1 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 MarR family DUF2250 PF10007.9 ABX13028.1 - 0.0045 17.1 0.1 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.19 ABX13028.1 - 0.0097 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PatG_C PF18065.1 ABX13028.1 - 0.034 14.1 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 PatG C-terminal LexA_DNA_bind PF01726.16 ABX13028.1 - 0.083 12.7 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 LexA DNA binding domain HipN PF18253.1 ABX13028.1 - 0.092 12.5 0.1 0.092 12.5 0.1 1.9 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain Kelch_1 PF01344.25 ABX13029.1 - 1.1e-54 181.8 7.7 1.1e-11 44.1 0.0 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 ABX13029.1 - 3.4e-36 122.3 8.1 2e-08 34.3 0.0 7.1 6 1 1 7 7 7 5 Kelch motif Kelch_2 PF07646.15 ABX13029.1 - 7.5e-35 117.6 2.1 8e-08 32.0 0.0 6.5 7 0 0 7 7 7 6 Kelch motif Kelch_5 PF13854.6 ABX13029.1 - 2.3e-26 91.3 1.6 0.00048 20.0 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 ABX13029.1 - 5.6e-26 90.3 9.3 7.9e-05 22.6 0.0 6.5 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 ABX13029.1 - 5.9e-18 64.7 11.6 0.0026 18.0 0.0 7.4 7 1 0 7 7 7 4 Galactose oxidase, central domain PQQ_3 PF13570.6 ABX13029.1 - 0.02 15.4 6.7 1.2 9.7 1.6 4.7 4 1 1 5 5 5 0 PQQ-like domain Glyoxal_oxid_N PF07250.11 ABX13029.1 - 0.034 13.3 0.0 0.33 10.1 0.0 2.2 1 1 1 2 2 2 0 Glyoxal oxidase N-terminus DUF5122 PF17164.4 ABX13029.1 - 0.036 14.3 5.0 14 6.1 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller Pur_ac_phosph_N PF16656.5 ABX13030.1 - 0.0023 18.5 0.1 0.0033 18.0 0.1 1.4 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Spermine_synth PF01564.17 ABX13031.1 - 1.5e-17 63.6 0.0 3.2e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_3 PF01596.17 ABX13031.1 - 4.7e-06 25.9 0.1 7.8e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_30 PF05430.11 ABX13031.1 - 0.00019 21.3 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 ABX13031.1 - 0.0078 16.9 0.0 0.014 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Tom6 PF17112.5 ABX13031.1 - 0.0084 15.6 4.4 0.22 11.1 0.1 2.7 2 0 0 2 2 2 1 Mitochondrial import receptor subunit Tom6, fungal Methyltransf_24 PF13578.6 ABX13031.1 - 0.02 15.9 0.0 0.04 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 ABX13031.1 - 0.025 13.9 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_12 PF08242.12 ABX13031.1 - 0.051 14.3 0.0 0.1 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cu-oxidase_3 PF07732.15 ABX13032.1 - 7.3e-34 116.3 2.5 6.5e-33 113.3 0.1 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ABX13032.1 - 2.6e-28 98.4 5.6 4.9e-22 78.2 0.9 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ABX13032.1 - 9.8e-13 48.5 0.4 1.7e-06 28.3 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase SoxE PF06525.11 ABX13032.1 - 0.025 14.1 0.2 0.37 10.2 0.0 2.5 2 0 0 2 2 2 0 Sulfocyanin (SoxE) domain Ferric_reduct PF01794.19 ABX13034.1 - 5.4e-09 36.2 10.0 5.4e-09 36.2 10.0 2.5 2 1 1 3 3 3 2 Ferric reductase like transmembrane component Glucos_trans_II PF14264.6 ABX13035.1 - 0.017 14.5 5.1 0.018 14.4 5.1 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII Thioredoxin_4 PF13462.6 ABX13036.1 - 3.4e-20 72.9 0.0 4.8e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ABX13036.1 - 7.2e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 ABX13036.1 - 0.00012 21.8 0.1 0.00021 21.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ABX13036.1 - 0.044 14.2 0.6 0.092 13.2 0.6 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain SapB_1 PF05184.15 ABX13037.1 - 0.18 11.9 0.3 35 4.5 0.0 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 GerD PF17898.1 ABX13037.1 - 0.3 11.0 57.5 0.42 10.6 22.5 3.3 1 1 2 3 3 3 0 Spore germination GerD central core domain Bep_C_terminal PF17841.1 ABX13037.1 - 1.7 8.9 10.1 8.6 6.7 0.1 3.2 1 1 2 3 3 3 0 BID domain of Bartonella effector protein (Bep) TetR_C_28 PF17937.1 ABX13037.1 - 2.8 8.4 9.9 3.6 8.1 0.3 3.8 1 1 3 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Copper-bind PF00127.20 ABX13038.1 - 1.3e-06 28.7 0.0 1.9e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX13038.1 - 0.00031 20.8 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain CbiM PF01891.16 ABX13038.1 - 0.056 13.3 0.5 0.071 12.9 0.5 1.1 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Lipase_C PF18067.1 ABX13038.1 - 0.13 12.8 0.0 0.18 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipase C-terminal domain Thioredoxin_4 PF13462.6 ABX13039.1 - 2e-34 119.1 0.0 2.4e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ABX13039.1 - 1.3e-13 51.2 0.0 1.7e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ABX13039.1 - 2.2e-07 31.3 0.0 3.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 ABX13039.1 - 5.7e-05 22.9 0.0 8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ABX13039.1 - 0.0017 18.6 0.0 1.3 9.4 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin PF00085.20 ABX13039.1 - 0.035 14.1 0.1 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin DsbD PF02683.15 ABX13040.1 - 5.9e-17 62.3 18.1 5.9e-17 62.3 18.1 2.2 2 1 1 3 3 3 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 ABX13040.1 - 4.3e-07 30.1 24.2 1.7e-06 28.1 8.8 2.4 1 1 1 2 2 2 2 Cytochrome C biogenesis protein transmembrane region DUF2723 PF11028.8 ABX13040.1 - 0.26 11.2 5.6 0.23 11.4 0.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2723) DUF3185 PF11381.8 ABX13040.1 - 0.7 10.0 19.0 3.1 7.9 0.1 4.9 4 2 1 5 5 5 0 Protein of unknown function (DUF3185) EamA PF00892.20 ABX13040.1 - 3 8.0 27.4 11 6.2 8.0 4.2 4 1 0 4 4 4 0 EamA-like transporter family Thioredoxin_3 PF13192.6 ABX13041.1 - 6.1e-15 55.0 1.3 6.8e-15 54.9 0.3 1.6 2 0 0 2 2 2 1 Thioredoxin domain Glutaredoxin PF00462.24 ABX13041.1 - 1.4e-10 41.2 0.2 2.2e-10 40.6 0.2 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 ABX13041.1 - 0.0005 20.4 0.0 0.00063 20.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 ABX13041.1 - 0.0011 19.3 0.0 0.0016 18.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain KaiB PF07689.12 ABX13041.1 - 0.0045 16.7 0.2 0.017 14.9 0.0 1.9 1 1 1 2 2 2 1 KaiB domain Thioredoxin PF00085.20 ABX13041.1 - 0.016 15.2 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 ABX13041.1 - 0.061 13.8 0.4 5.4 7.5 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 ABX13041.1 - 0.065 13.0 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Trypsin_2 PF13365.6 ABX13042.1 - 2.3e-36 125.9 0.8 1e-35 123.9 0.4 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 ABX13042.1 - 1.9e-14 53.8 1.1 4.8e-14 52.4 0.3 2.1 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 ABX13042.1 - 3e-12 46.9 0.1 5.7e-12 45.9 0.1 1.5 1 1 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 ABX13042.1 - 1.6e-06 27.8 1.3 0.018 14.9 0.1 3.2 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 ABX13042.1 - 0.00048 20.4 1.0 1.9 8.9 0.4 3.5 3 0 0 3 3 3 1 PDZ domain Peptidase_S29 PF02907.15 ABX13042.1 - 0.0035 17.1 0.4 0.011 15.5 0.1 2.0 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 ABX13042.1 - 0.011 14.4 1.9 0.022 13.4 0.5 1.8 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S32 PF05579.13 ABX13042.1 - 0.019 14.2 2.2 1.5 8.0 0.1 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 DUF31 PF01732.16 ABX13042.1 - 0.04 13.4 0.1 7.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 ABX13042.1 - 0.058 13.2 0.5 0.16 11.8 0.5 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Big_8 PF17961.1 ABX13042.1 - 0.065 13.4 0.2 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 Bacterial Ig domain HTH_AsnC-type PF13404.6 ABX13043.1 - 5.3e-14 51.8 0.2 7.6e-14 51.3 0.2 1.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABX13043.1 - 3.5e-12 45.7 0.6 6.5e-12 44.8 0.6 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Arc_trans_TRASH PF08394.10 ABX13043.1 - 1.5e-07 31.6 5.5 2.6e-07 30.8 5.5 1.4 1 0 0 1 1 1 1 Archaeal TRASH domain HTH_Tnp_ISL3 PF13542.6 ABX13043.1 - 0.00052 19.4 0.0 0.00078 18.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 TrmB PF01978.19 ABX13043.1 - 0.00061 19.6 0.0 0.0019 18.1 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 ABX13043.1 - 0.00081 19.2 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 ABX13043.1 - 0.0036 17.1 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 ABX13043.1 - 0.0094 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 MarR family DUF2250 PF10007.9 ABX13043.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_28 PF13518.6 ABX13043.1 - 0.02 15.0 0.1 0.039 14.1 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABX13043.1 - 0.02 14.6 0.0 0.051 13.2 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_38 PF13936.6 ABX13043.1 - 0.028 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain zf-UDP PF14569.6 ABX13043.1 - 0.049 13.7 2.5 0.14 12.3 2.8 1.6 2 0 0 2 2 2 0 Zinc-binding RING-finger HTH_IclR PF09339.10 ABX13043.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_psq PF05225.16 ABX13043.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Thioredoxin_4 PF13462.6 ABX13044.1 - 1.1e-38 133.0 0.0 1.4e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ABX13044.1 - 1.4e-19 70.7 0.1 3.4e-10 40.0 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ABX13044.1 - 6.8e-11 42.6 0.0 1.7e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 ABX13044.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 ABX13046.1 - 8.7e-39 133.3 0.0 1.1e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ABX13046.1 - 6.4e-14 52.2 0.2 6.1e-12 45.7 0.2 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ABX13046.1 - 4.8e-05 23.8 0.1 0.0001 22.7 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 ABX13046.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF3892 PF13031.6 ABX13047.1 - 0.0016 19.0 0.0 0.0024 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3892) DUF1533 PF07550.11 ABX13047.1 - 0.02 14.8 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Gemin6 PF06372.12 ABX13047.1 - 0.03 13.9 0.2 0.039 13.5 0.2 1.2 1 0 0 1 1 1 0 Gemin6 protein TrmB PF01978.19 ABX13048.1 - 8.7e-06 25.5 0.1 1.3e-05 25.0 0.1 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 ABX13048.1 - 0.0029 17.4 0.5 0.0049 16.7 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABX13048.1 - 0.014 15.5 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 ABX13048.1 - 0.014 15.3 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 HTH domain Mga PF05043.13 ABX13048.1 - 0.053 14.1 2.1 0.57 10.8 0.3 2.1 1 1 1 2 2 2 0 Mga helix-turn-helix domain HTH_IclR PF09339.10 ABX13048.1 - 0.082 12.7 0.0 0.14 11.9 0.0 1.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain MADF_DNA_bdg PF10545.9 ABX13048.1 - 0.11 12.8 0.0 0.41 11.0 0.0 1.8 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DsbD_2 PF13386.6 ABX13049.1 - 1.7e-05 24.8 8.6 9.1e-05 22.5 7.8 2.1 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region NicO PF03824.16 ABX13049.1 - 5.3e-05 22.7 13.9 5.3e-05 22.7 13.9 1.6 1 1 1 2 2 2 1 High-affinity nickel-transport protein Phage_holin_3_6 PF07332.11 ABX13049.1 - 0.0014 18.6 6.9 0.0087 16.1 0.3 2.2 2 0 0 2 2 2 2 Putative Actinobacterial Holin-X, holin superfamily III DUF2370 PF10176.9 ABX13049.1 - 0.062 12.9 1.9 0.086 12.5 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Halogen_Hydrol PF10112.9 ABX13049.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.4 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TetR_C_28 PF17937.1 ABX13050.1 - 0.0011 19.3 13.1 0.025 15.1 0.2 5.5 2 2 2 5 5 5 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 ABX13050.1 - 0.0028 18.0 0.2 3.7 7.9 0.0 4.1 3 2 2 5 5 5 1 Tetracyclin repressor-like, C-terminal domain MethyTransf_Reg PF10119.9 ABX13050.1 - 0.32 11.7 15.0 1.4 9.7 0.3 5.3 3 2 3 6 6 6 0 Predicted methyltransferase regulatory domain Bep_C_terminal PF17841.1 ABX13050.1 - 0.59 10.4 24.7 4.4 7.6 0.2 6.2 4 3 2 6 6 6 0 BID domain of Bartonella effector protein (Bep) Yip1 PF04893.17 ABX13050.1 - 0.77 9.5 0.0 0.77 9.5 0.0 2.3 3 0 0 3 3 3 0 Yip1 domain SATase_N PF06426.14 ABX13050.1 - 0.85 10.0 5.4 26 5.2 0.3 3.9 2 2 1 4 4 4 0 Serine acetyltransferase, N-terminal HTH_5 PF01022.20 ABX13051.1 - 3e-18 65.4 0.3 4.8e-18 64.8 0.3 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABX13051.1 - 5.2e-09 36.0 0.0 7.7e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 ABX13051.1 - 6.9e-07 29.1 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 ABX13051.1 - 1.4e-06 28.0 0.0 2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABX13051.1 - 8.5e-06 26.2 0.0 1.4e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 ABX13051.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 ABX13051.1 - 5.9e-05 22.5 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 ABX13051.1 - 0.00016 21.5 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 MarR family DUF4423 PF14394.6 ABX13051.1 - 0.00026 20.7 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_45 PF14947.6 ABX13051.1 - 0.00035 20.5 0.3 0.0017 18.3 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix Fe_dep_repress PF01325.19 ABX13051.1 - 0.0029 17.8 0.1 0.0077 16.4 0.0 1.7 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 ABX13051.1 - 0.008 16.5 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator GerE PF00196.19 ABX13051.1 - 0.0081 15.7 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_34 PF13601.6 ABX13051.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_47 PF16221.5 ABX13051.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 winged helix-turn-helix ArsR PF09824.9 ABX13051.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 ArsR transcriptional regulator Penicillinase_R PF03965.16 ABX13051.1 - 0.043 14.2 0.0 0.057 13.8 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor HTH_9 PF08221.11 ABX13051.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_1 PF00126.27 ABX13051.1 - 0.18 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Cation_efflux PF01545.21 ABX13052.1 - 1.9e-18 67.0 13.2 8.3e-17 61.6 13.2 2.0 1 1 0 1 1 1 1 Cation efflux family DUF1358 PF07096.11 ABX13052.1 - 0.16 12.0 0.9 0.34 10.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) DarT PF14487.6 ABX13054.1 - 2.6e-46 158.0 0.4 3.5e-46 157.6 0.4 1.1 1 0 0 1 1 1 1 ssDNA thymidine ADP-ribosyltransferase, DarT Macro PF01661.21 ABX13054.1 - 1.3e-09 38.1 0.0 6.4e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Macro domain Cons_hypoth95 PF03602.15 ABX13055.1 - 0.03 13.9 0.2 0.8 9.3 0.2 2.2 1 1 0 1 1 1 0 Conserved hypothetical protein 95 DUF5131 PF07505.11 ABX13056.1 - 2.4e-81 272.9 0.8 2.7e-81 272.7 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF5131) GIY-YIG PF01541.24 ABX13058.1 - 0.00095 19.4 2.4 0.0013 19.0 2.4 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain DUF456 PF04306.13 ABX13060.1 - 0.005 17.1 1.6 0.0064 16.8 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) DUF1269 PF06897.12 ABX13060.1 - 0.2 12.0 8.4 0.68 10.2 7.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) Gly-zipper_YMGG PF13441.6 ABX13060.1 - 1.9 8.3 16.3 3.5 7.5 16.3 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 ABX13060.1 - 2.5 8.3 11.4 4.4 7.5 11.4 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide MT-A70 PF05063.14 ABX13061.1 - 4.7e-26 91.7 0.3 1.8e-25 89.8 0.0 2.0 3 0 0 3 3 3 1 MT-A70 N6_N4_Mtase PF01555.18 ABX13061.1 - 0.03 14.0 0.1 0.05 13.3 0.1 1.4 1 1 0 1 1 1 0 DNA methylase ParBc PF02195.18 ABX13062.1 - 3.6e-14 52.8 0.0 3.7e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_DeoR PF08220.12 ABX13063.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Penicillinase_R PF03965.16 ABX13064.1 - 0.0055 17.0 0.1 0.015 15.6 0.1 1.7 2 0 0 2 2 2 1 Penicillinase repressor Phage_integrase PF00589.22 ABX13065.1 - 1.6e-05 24.8 0.8 0.0084 15.9 0.1 3.0 3 1 0 3 3 3 2 Phage integrase family Flavodoxin_2 PF02525.17 ABX13066.1 - 2.6e-30 105.6 0.0 3.4e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 ABX13066.1 - 9e-05 22.3 0.0 0.00035 20.3 0.0 1.9 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Osmo_CC PF08946.10 ABX13066.1 - 0.00029 21.0 0.8 0.00049 20.3 0.8 1.4 1 0 0 1 1 1 1 Osmosensory transporter coiled coil DUF2110 PF09883.9 ABX13066.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) DUF393 PF04134.12 ABX13067.1 - 0.00018 22.8 0.0 0.00023 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 VKG_Carbox PF05090.14 ABX13068.1 - 1.1e-129 433.1 22.2 1.3e-129 432.9 22.2 1.0 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase Internalin_N PF12354.8 ABX13070.1 - 0.12 12.5 0.4 0.2 11.7 0.4 1.3 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal Pyrophosphatase PF00719.19 ABX13071.1 - 1.7e-56 190.5 0.1 1.9e-56 190.3 0.1 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase S-layer PF07752.11 ABX13071.1 - 0.014 14.5 0.1 0.025 13.6 0.1 1.4 1 0 0 1 1 1 0 S-layer protein zf-UBP PF02148.19 ABX13072.1 - 3.9e-12 46.3 8.6 6.8e-12 45.5 8.6 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 ABX13072.1 - 0.0064 16.2 0.9 0.01 15.6 0.9 1.4 1 0 0 1 1 1 1 Variant UBP zinc finger Peptidase_M3 PF01432.20 ABX13073.1 - 2.1e-44 152.5 0.3 9.9e-44 150.3 0.3 2.0 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 ABX13073.1 - 0.001 19.3 0.2 0.001 19.3 0.2 3.6 3 1 0 3 3 3 1 Oligopeptidase F Peptidase_M78 PF06114.13 ABX13073.1 - 0.0085 16.0 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 IrrE N-terminal-like domain Colicin PF01024.19 ABX13073.1 - 0.071 13.0 2.1 1.4 8.8 0.2 2.9 2 0 0 2 2 2 0 Colicin pore forming domain DUF892 PF05974.12 ABX13073.1 - 0.08 13.0 0.2 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF892) NPV_P10 PF05531.12 ABX13073.1 - 0.093 13.2 2.2 0.22 12.0 0.3 2.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF840 PF05801.11 ABX13073.1 - 0.12 12.5 1.2 0.92 9.6 0.2 2.4 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) Suppressor_APC PF11414.8 ABX13073.1 - 0.15 12.1 1.1 1.8 8.7 0.3 2.7 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DUF1890 PF09001.11 ABX13075.1 - 0.04 14.3 0.2 0.077 13.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) PvlArgDC PF01862.16 ABX13076.1 - 4.2e-57 192.5 0.0 4.8e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Thioredoxin_4 PF13462.6 ABX13077.1 - 2.6e-42 144.8 0.0 4.6e-42 144.0 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.20 ABX13077.1 - 4.6e-19 68.9 0.5 4.2e-17 62.6 0.5 2.2 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ABX13077.1 - 5.8e-11 42.8 0.0 1.1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 ABX13077.1 - 0.00017 21.4 0.1 0.00024 20.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin DUF682 PF05081.12 ABX13077.1 - 0.052 13.3 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF682) EssA PF10661.9 ABX13077.1 - 0.08 12.8 0.1 8.1 6.3 0.0 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA DEAD PF00270.29 ABX13078.1 - 4.7e-50 169.8 0.0 4.5e-49 166.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ABX13078.1 - 2.6e-31 108.2 0.1 9.5e-30 103.2 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 ABX13078.1 - 2.2e-05 23.8 0.1 3.2e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 ABX13078.1 - 0.0016 18.4 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ABX13078.1 - 0.0023 17.7 0.4 0.0062 16.3 0.2 1.8 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 ABX13078.1 - 0.0078 15.6 0.2 0.027 13.8 0.1 1.9 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit AsnC_trans_reg PF01037.21 ABX13079.1 - 4.3e-06 26.6 0.1 4.4e-06 26.6 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GYD PF08734.11 ABX13079.1 - 0.00023 21.0 0.1 0.00025 20.9 0.1 1.1 1 0 0 1 1 1 1 GYD domain NapD PF03927.13 ABX13079.1 - 0.032 14.3 0.5 2.4 8.3 0.1 1.9 1 1 1 2 2 2 0 NapD protein RPN6_C_helix PF18503.1 ABX13079.1 - 0.078 12.7 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 26S proteasome subunit RPN6 C-terminal helix domain DUF465 PF04325.13 ABX13080.1 - 0.16 12.0 0.4 0.27 11.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Phage_HK97_TLTM PF06120.11 ABX13081.1 - 0.081 12.1 1.0 0.15 11.2 0.1 1.8 2 0 0 2 2 2 0 Tail length tape measure protein FliE PF02049.18 ABX13081.1 - 0.23 11.6 1.8 0.35 11.0 0.1 2.0 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE DUF3426 PF11906.8 ABX13082.1 - 2.2e-15 57.1 0.2 1.5e-08 34.9 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3426) DUF2393 PF09624.10 ABX13082.1 - 0.016 15.2 3.7 0.15 12.1 0.1 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF2393) Laminin_II PF06009.12 ABX13083.1 - 0.021 14.9 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Laminin Domain II zinc_ribbon_2 PF13240.6 ABX13084.1 - 5.5e-06 25.9 1.0 1.6e-05 24.4 1.0 1.9 1 0 0 1 1 1 1 zinc-ribbon domain CBM_14 PF01607.24 ABX13084.1 - 4.3e-05 23.6 2.1 4.2 7.6 0.1 3.4 1 1 2 3 3 3 3 Chitin binding Peritrophin-A domain DZR PF12773.7 ABX13084.1 - 9e-05 22.4 0.2 0.00027 20.9 0.2 1.8 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 ABX13084.1 - 0.00031 20.0 1.0 0.00087 18.6 1.0 1.9 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 ABX13084.1 - 0.00058 20.6 1.0 0.0015 19.2 1.0 1.7 1 0 0 1 1 1 1 zinc-ribbon family Ntox50 PF15542.6 ABX13084.1 - 0.18 12.6 1.5 0.33 11.8 0.5 1.9 2 0 0 2 2 2 0 Bacterial toxin 50 zf-Tim10_DDP PF02953.15 ABX13084.1 - 0.48 10.1 5.1 47 3.7 1.1 3.7 2 1 0 3 3 3 0 Tim10/DDP family zinc finger MCM6_C PF18263.1 ABX13085.1 - 0.0027 17.9 0.4 0.0043 17.3 0.4 1.4 1 1 0 1 1 1 1 MCM6 C-terminal winged-helix domain Arcadin_1 PF18653.1 ABX13086.1 - 0.00013 22.0 1.2 0.00016 21.7 1.2 1.1 1 0 0 1 1 1 1 Arcadin 1 Thioredox_DsbH PF03190.15 ABX13087.1 - 2.7e-77 258.3 0.1 4.6e-77 257.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 ABX13087.1 - 9.6e-12 44.9 0.0 2.1e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.13 ABX13087.1 - 1.6e-06 27.8 0.9 0.11 11.9 0.1 3.8 3 1 1 4 4 4 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 ABX13087.1 - 3e-05 23.3 0.0 0.14 11.2 0.0 3.0 2 2 2 4 4 4 2 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 ABX13087.1 - 0.0042 16.4 0.0 3 7.0 0.0 2.9 2 1 1 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_127 PF07944.12 ABX13087.1 - 0.0087 14.6 0.0 0.097 11.1 0.0 2.5 1 1 1 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Thioredoxin_2 PF13098.6 ABX13087.1 - 0.024 15.1 0.0 0.06 13.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain LANC_like PF05147.13 ABX13087.1 - 0.035 12.7 3.6 7.1 5.1 0.0 4.5 5 1 0 5 5 5 0 Lanthionine synthetase C-like protein Glyco_hydro_76 PF03663.14 ABX13087.1 - 0.049 13.1 0.0 3.9 6.9 0.0 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase family 76 Pec_lyase PF09492.10 ABX13087.1 - 0.1 11.9 0.1 14 4.9 0.0 2.2 2 0 0 2 2 2 0 Pectic acid lyase Lactococcin_972 PF09683.10 ABX13088.1 - 0.11 13.1 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) ADH_N PF08240.12 ABX13089.1 - 2.2e-30 104.8 1.3 4.1e-30 103.9 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABX13089.1 - 4.8e-19 68.6 0.3 7.6e-19 68.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ABX13089.1 - 0.00017 21.0 0.0 0.00038 19.9 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ABX13089.1 - 0.00039 19.8 0.7 0.0007 18.9 0.7 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF4443 PF14544.6 ABX13089.1 - 0.0077 16.4 0.2 0.017 15.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4443) NAD_binding_2 PF03446.15 ABX13089.1 - 0.029 14.5 0.2 0.051 13.7 0.2 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N_2 PF13602.6 ABX13089.1 - 0.041 14.9 0.0 0.077 14.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 ABX13089.1 - 0.046 13.6 0.3 0.097 12.6 0.3 1.6 1 1 0 1 1 1 0 NAD(P)H-binding CoA_binding PF02629.19 ABX13089.1 - 0.047 14.4 6.5 0.11 13.2 3.0 3.1 2 1 1 3 3 3 0 CoA binding domain GFO_IDH_MocA PF01408.22 ABX13089.1 - 0.076 13.8 1.2 0.27 12.0 0.2 2.1 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF1460 PF07313.12 ABX13089.1 - 0.14 11.5 0.0 0.32 10.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1460) Zn_Tnp_IS1595 PF12760.7 ABX13090.1 - 0.0013 18.7 3.1 0.0013 18.7 3.1 1.8 2 0 0 2 2 2 1 Transposase zinc-ribbon domain C1_2 PF03107.16 ABX13090.1 - 0.012 15.9 1.7 0.029 14.7 1.7 1.6 1 0 0 1 1 1 0 C1 domain zf-TFIIB PF13453.6 ABX13090.1 - 0.043 13.2 4.9 0.082 12.2 4.1 1.9 2 0 0 2 2 2 0 Transcription factor zinc-finger OrfB_Zn_ribbon PF07282.11 ABX13090.1 - 0.083 12.8 2.8 0.17 11.8 2.8 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 ABX13090.1 - 0.09 12.9 4.0 3.1 8.0 1.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.19 ABX13090.1 - 0.22 11.5 3.0 0.32 11.0 3.0 1.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Desulfoferrod_N PF06397.12 ABX13090.1 - 0.84 9.3 4.1 13 5.5 0.1 2.8 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Rad50_zn_hook PF04423.14 ABX13090.1 - 0.86 9.5 5.1 1.3 9.0 1.6 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Mss51 PF13824.6 ABX13090.1 - 3.9 7.6 5.6 25 5.1 1.7 2.4 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 AsnC_trans_reg PF01037.21 ABX13093.1 - 2.6e-10 40.1 0.0 2.7e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GYD PF08734.11 ABX13093.1 - 0.0015 18.4 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 GYD domain Staph_opine_DH PF10100.9 ABX13093.1 - 0.049 12.3 0.1 0.056 12.1 0.1 1.0 1 0 0 1 1 1 0 Staphylopine dehydrogenase TruD PF01142.18 ABX13094.1 - 7.6e-86 288.5 2.6 3e-85 286.5 2.6 1.7 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) RdRP_4 PF02123.16 ABX13094.1 - 0.095 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase SGL PF08450.12 ABX13095.1 - 1.8e-08 34.3 1.4 0.011 15.4 0.0 4.6 2 2 3 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 ABX13095.1 - 9.5e-08 32.1 0.7 0.0059 16.6 0.1 4.7 4 1 1 5 5 5 1 Domain of unknown function (DUF5074) Reg_prop PF07494.11 ABX13095.1 - 0.0029 17.6 7.1 4.3 7.9 0.2 5.3 5 0 0 5 5 5 2 Two component regulator propeller NHL PF01436.21 ABX13095.1 - 0.099 12.7 0.0 3 8.1 0.0 3.1 2 0 0 2 2 2 0 NHL repeat PTH2 PF01981.16 ABX13096.1 - 4.5e-40 136.6 0.1 5.1e-40 136.4 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Response_reg PF00072.24 ABX13098.1 - 7.3e-24 84.1 1.8 8.3e-24 83.9 1.8 1.0 1 0 0 1 1 1 1 Response regulator receiver domain SDP_N PF12278.8 ABX13099.1 - 0.029 14.5 0.1 0.062 13.4 0.1 1.5 1 0 0 1 1 1 0 Sex determination protein N terminal 7TM-7TMR_HD PF07698.11 ABX13100.1 - 0.047 13.5 0.2 0.047 13.5 0.2 1.9 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Phage_gp53 PF11246.8 ABX13101.1 - 0.0074 16.0 1.7 0.013 15.1 1.7 1.4 1 0 0 1 1 1 1 Base plate wedge protein 53 Response_reg PF00072.24 ABX13102.1 - 7.3e-24 84.1 1.1 8.5e-24 83.9 1.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Root_cap PF06830.11 ABX13102.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Root cap HATPase_c PF02518.26 ABX13103.1 - 1.6e-16 60.8 0.1 3.6e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 ABX13103.1 - 2.9e-14 53.4 4.8 2.9e-14 53.4 4.8 2.1 2 0 0 2 2 2 1 Cache domain HisKA PF00512.25 ABX13103.1 - 4.4e-10 39.4 0.0 1.7e-09 37.5 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ABX13103.1 - 1.5e-07 31.7 0.0 4.4e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 HAMP domain HATPase_c_5 PF14501.6 ABX13103.1 - 9.1e-06 25.5 0.1 9.1e-06 25.5 0.1 2.7 4 0 0 4 4 4 1 GHKL domain HATPase_c_2 PF13581.6 ABX13103.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain IL5 PF02025.15 ABX13103.1 - 0.073 13.4 0.5 17 5.8 0.1 2.7 2 0 0 2 2 2 0 Interleukin 5 HTH_WhiA PF02650.14 ABX13103.1 - 3.2 8.1 6.2 3 8.3 1.4 3.1 2 1 1 3 3 3 0 WhiA C-terminal HTH domain BLOC1_2 PF10046.9 ABX13103.1 - 3.9 7.8 8.7 63 4.0 1.1 3.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GRP PF07172.11 ABX13104.1 - 0.029 15.0 0.0 0.039 14.6 0.0 1.2 1 0 0 1 1 1 0 Glycine rich protein family DUF3742 PF12553.8 ABX13104.1 - 0.048 13.8 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) HD PF01966.22 ABX13106.1 - 3.5e-15 56.3 0.4 1.1e-14 54.7 0.1 1.9 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 ABX13106.1 - 0.00054 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 HDOD domain YgbB PF02542.16 ABX13106.1 - 0.092 13.0 0.6 17 5.7 0.0 2.3 2 0 0 2 2 2 0 YgbB family PASTA PF03793.19 ABX13107.1 - 0.056 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 PASTA domain Metallophos PF00149.28 ABX13108.1 - 1.4e-14 55.1 0.9 5.3e-14 53.2 0.6 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ABX13108.1 - 9.7e-09 35.6 0.0 1.8e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NIF3 PF01784.18 ABX13108.1 - 0.019 14.6 0.0 0.053 13.2 0.0 1.5 1 1 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) DUF2536 PF10750.9 ABX13108.1 - 8.1 6.4 7.8 5.9 6.9 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) AAA_23 PF13476.6 ABX13109.1 - 9.3e-17 62.2 18.7 9.3e-17 62.2 18.7 6.0 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.6 ABX13109.1 - 6.5e-07 29.0 0.1 1.5e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 ABX13109.1 - 0.0057 16.3 0.1 0.0057 16.3 0.1 4.1 4 1 1 5 5 5 1 AAA domain AAA_13 PF13166.6 ABX13109.1 - 0.0078 14.9 0.2 0.0078 14.9 0.2 5.4 2 1 3 6 6 6 1 AAA domain AAA_31 PF13614.6 ABX13110.1 - 2.1e-29 102.7 0.0 3.2e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ABX13110.1 - 2.2e-13 50.4 0.0 3.3e-13 49.8 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 ABX13110.1 - 1.8e-07 30.6 0.0 3.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase Fer4_NifH PF00142.18 ABX13110.1 - 3.9e-06 26.5 0.0 1.6e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 ABX13110.1 - 5.3e-06 26.1 0.0 0.00027 20.5 0.0 2.2 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 ABX13110.1 - 7.1e-06 25.5 0.0 2.6e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 ATPase MipZ ParA PF10609.9 ABX13110.1 - 1.3e-05 24.8 0.0 0.00036 20.1 0.0 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase VirC1 PF07015.11 ABX13110.1 - 0.011 15.1 0.0 0.31 10.3 0.0 2.1 2 0 0 2 2 2 0 VirC1 protein ATP_bind_1 PF03029.17 ABX13110.1 - 0.026 14.3 0.1 0.052 13.3 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 ABX13110.1 - 0.05 13.2 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CLP1_P PF16575.5 ABX13110.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Iron_traffic PF04362.14 ABX13110.1 - 0.091 12.5 0.6 0.17 11.6 0.2 1.6 1 1 0 1 1 1 0 Bacterial Fe(2+) trafficking MeaB PF03308.16 ABX13110.1 - 0.093 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4508 PF14969.6 ABX13110.1 - 0.71 10.2 4.0 5 7.4 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4508) DUF3921 PF13060.6 ABX13112.1 - 0.0046 17.0 0.8 0.022 14.8 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3921) HTH_19 PF12844.7 ABX13112.1 - 0.01 15.8 2.8 1.3 9.0 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 ABX13112.1 - 0.035 14.4 0.5 0.88 9.9 0.0 3.3 4 1 0 4 4 4 0 Transposase DUF3287 PF11690.8 ABX13112.1 - 0.047 13.4 5.6 3.6 7.3 0.1 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF3287) HTH_26 PF13443.6 ABX13112.1 - 0.064 13.7 0.9 30 5.2 0.0 4.0 4 0 0 4 4 4 0 Cro/C1-type HTH DNA-binding domain Acetyltransf_11 PF13720.6 ABX13112.1 - 0.082 13.4 4.8 7.4 7.1 0.1 3.9 4 1 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF3349 PF11829.8 ABX13112.1 - 0.33 11.7 7.4 0.8 10.5 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3349) DUF3877 PF12993.7 ABX13112.1 - 0.62 9.9 11.2 0.022 14.6 2.4 2.8 3 1 0 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF3450 PF11932.8 ABX13112.1 - 2.1 7.6 24.1 0.48 9.7 1.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.7 ABX13112.1 - 2.6 8.2 46.5 0.046 13.9 18.9 4.0 2 2 1 3 3 3 0 Tropomyosin like DUF948 PF06103.11 ABX13112.1 - 7 7.0 15.1 13 6.1 1.2 4.6 4 1 2 6 6 6 0 Bacterial protein of unknown function (DUF948) UPF0167 PF03691.14 ABX13113.1 - 0.55 10.0 6.5 0.81 9.5 5.9 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) Complex1_LYR_2 PF13233.6 ABX13114.1 - 0.078 13.7 4.1 0.14 12.9 1.9 2.8 2 1 0 2 2 2 0 Complex1_LYR-like Phage_integrase PF00589.22 ABX13115.1 - 1.8e-06 27.8 0.4 5.9e-06 26.2 0.4 1.7 1 1 0 1 1 1 1 Phage integrase family ATP-cone PF03477.16 ABX13115.1 - 0.018 15.6 0.0 1.5 9.4 0.0 2.5 2 0 0 2 2 2 0 ATP cone domain Phage_int_SAM_1 PF02899.17 ABX13115.1 - 0.046 14.0 0.8 0.61 10.4 0.0 3.0 3 1 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 ABX13115.1 - 0.05 14.1 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FAD_binding_3 PF01494.19 ABX13116.1 - 4.1e-08 32.8 1.1 0.0079 15.5 0.0 2.8 1 1 1 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ABX13116.1 - 4e-07 29.4 0.0 0.00014 21.1 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 ABX13116.1 - 2.2e-05 24.2 0.3 0.0041 16.7 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ABX13116.1 - 5.7e-05 22.6 0.1 0.00039 19.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABX13116.1 - 7.4e-05 21.6 1.1 0.0024 16.7 0.1 2.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 ABX13116.1 - 0.00031 20.1 0.3 0.00069 18.9 0.3 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ABX13116.1 - 0.00033 20.8 0.3 0.0062 16.8 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ABX13116.1 - 0.00045 19.4 1.0 0.0014 17.8 1.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ABX13116.1 - 0.00088 18.6 2.7 0.026 13.8 2.7 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ABX13116.1 - 0.027 13.3 1.0 2.1 7.1 0.0 2.9 2 1 0 2 2 2 0 Tryptophan halogenase Peptidase_C6 PF00851.18 ABX13116.1 - 0.094 11.6 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Helper component proteinase zf-HIT PF04438.16 ABX13117.1 - 0.002 17.9 9.9 0.01 15.7 3.9 2.3 2 1 0 2 2 2 1 HIT zinc finger DUF1610 PF07754.11 ABX13117.1 - 0.012 15.6 1.8 0.012 15.6 1.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) DZR PF12773.7 ABX13117.1 - 0.037 14.1 10.7 0.27 11.3 10.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon DUF2321 PF10083.9 ABX13117.1 - 0.072 12.7 3.3 0.092 12.4 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zinc_ribbon_2 PF13240.6 ABX13117.1 - 0.087 12.6 1.1 0.087 12.6 1.1 2.9 2 1 0 2 2 2 0 zinc-ribbon domain zf-tcix PF14952.6 ABX13117.1 - 0.16 11.6 7.8 0.44 10.2 7.8 1.9 1 1 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Rubredoxin_2 PF18073.1 ABX13117.1 - 0.17 11.7 14.7 7 6.5 7.6 3.1 2 1 0 2 2 2 0 Rubredoxin metal binding domain zf_UBZ PF18439.1 ABX13117.1 - 0.19 11.4 7.4 2.9 7.5 0.3 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 ABX13117.1 - 0.21 11.5 13.5 0.85 9.6 0.2 3.0 1 1 2 3 3 3 0 Probable zinc-ribbon domain zf-B_box PF00643.24 ABX13117.1 - 0.22 11.7 8.7 1.1 9.5 8.7 2.0 1 1 0 1 1 1 0 B-box zinc finger zf-ribbon_3 PF13248.6 ABX13117.1 - 0.23 10.9 0.2 0.23 10.9 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 ABX13117.1 - 0.31 10.8 11.9 4 7.2 0.5 3.0 1 1 2 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 ABX13117.1 - 0.32 11.0 14.3 0.69 9.9 14.3 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-CHY PF05495.12 ABX13117.1 - 0.32 11.5 9.7 0.53 10.8 9.7 1.4 1 1 0 1 1 1 0 CHY zinc finger Zn_Tnp_IS1 PF03811.13 ABX13117.1 - 0.48 10.2 9.2 1 9.2 9.2 1.9 1 1 0 1 1 1 0 InsA N-terminal domain A2L_zn_ribbon PF08792.10 ABX13117.1 - 0.82 9.5 10.1 2.9 7.7 0.7 3.0 3 0 0 3 3 3 0 A2L zinc ribbon domain PolC_DP2 PF03833.13 ABX13117.1 - 1 7.1 6.6 1.1 7.0 6.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_2 PF03107.16 ABX13117.1 - 2.3 8.6 12.4 29 5.1 12.4 2.0 1 1 0 1 1 1 0 C1 domain zf-Mss51 PF13824.6 ABX13117.1 - 2.4 8.3 10.0 0.27 11.4 1.1 2.1 1 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 EF1_GNE PF00736.19 ABX13118.1 - 5.4e-18 64.9 0.0 6.1e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain AAA PF00004.29 ABX13119.1 - 3.5e-89 296.0 0.0 4.7e-47 159.7 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ABX13119.1 - 4.7e-30 103.1 1.9 7.6e-14 51.2 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 ABX13119.1 - 1.2e-25 89.5 0.7 5.9e-25 87.3 0.7 2.2 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 ABX13119.1 - 4e-15 55.9 0.0 1.3e-08 34.7 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ABX13119.1 - 1.2e-12 48.3 0.0 3.4e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ABX13119.1 - 1.4e-11 45.1 0.2 0.0062 16.9 0.0 4.4 2 2 0 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.17 ABX13119.1 - 6.5e-11 41.9 0.8 2.3e-10 40.1 0.5 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 ABX13119.1 - 2.5e-10 40.5 0.0 8.2e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ABX13119.1 - 4.3e-10 39.7 0.1 0.00017 21.6 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ABX13119.1 - 4.6e-10 39.9 0.8 0.027 14.7 0.0 4.3 2 2 1 3 3 3 2 AAA domain ATPase_2 PF01637.18 ABX13119.1 - 1.3e-08 35.1 0.0 0.0012 18.8 0.0 3.5 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_33 PF13671.6 ABX13119.1 - 1.3e-08 35.1 0.0 0.0052 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ABX13119.1 - 1.5e-08 35.0 0.0 0.0026 18.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 ABX13119.1 - 1e-07 31.8 0.2 0.3 10.6 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 ABX13119.1 - 6.8e-07 29.9 0.0 0.058 13.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 ABX13119.1 - 1.3e-06 29.0 0.0 0.032 14.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter IstB_IS21 PF01695.17 ABX13119.1 - 2.1e-06 27.6 0.1 0.06 13.1 0.0 2.9 3 1 0 3 3 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 ABX13119.1 - 2.8e-06 27.7 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 ABX13119.1 - 4e-06 26.3 0.1 0.17 11.2 0.1 3.5 3 0 0 3 3 3 2 KaiC AAA_24 PF13479.6 ABX13119.1 - 8.5e-06 25.6 0.1 0.058 13.1 0.0 3.3 3 1 0 3 3 3 2 AAA domain Rad17 PF03215.15 ABX13119.1 - 8.5e-06 25.8 0.4 0.24 11.3 0.0 3.2 2 2 1 3 3 3 2 Rad17 P-loop domain Mg_chelatase PF01078.21 ABX13119.1 - 1.2e-05 24.8 1.1 0.02 14.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ABX13119.1 - 5.2e-05 23.2 0.2 1.1 9.2 0.0 3.5 3 0 0 3 3 3 1 NACHT domain Vps4_C PF09336.10 ABX13119.1 - 0.00012 22.0 0.4 0.37 10.8 0.1 2.9 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 ABX13119.1 - 0.00016 21.0 0.0 0.33 10.1 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 ABX13119.1 - 0.0002 21.5 0.0 0.44 10.7 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain TsaE PF02367.17 ABX13119.1 - 0.0003 20.8 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 ABX13119.1 - 0.00076 19.3 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 ABX13119.1 - 0.0012 18.7 0.1 0.72 9.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 ABX13119.1 - 0.0016 18.2 0.0 0.77 9.4 0.0 3.5 3 1 0 3 3 3 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 ABX13119.1 - 0.0018 17.6 0.3 1.9 7.7 0.1 2.8 3 0 0 3 3 3 1 Zeta toxin PhoH PF02562.16 ABX13119.1 - 0.0021 17.6 1.0 1.5 8.3 0.0 3.4 3 0 0 3 3 3 1 PhoH-like protein UFD1 PF03152.14 ABX13119.1 - 0.0027 17.2 0.1 0.0051 16.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AAA_7 PF12775.7 ABX13119.1 - 0.0032 17.0 0.1 0.74 9.3 0.0 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 ABX13119.1 - 0.0057 15.8 0.0 5.8 6.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF815) DUF2075 PF09848.9 ABX13119.1 - 0.006 15.9 0.0 2.4 7.3 0.1 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Adeno_IVa2 PF02456.15 ABX13119.1 - 0.0087 14.9 0.1 3.8 6.2 0.1 2.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein KAP_NTPase PF07693.14 ABX13119.1 - 0.015 14.5 0.2 13 5.0 0.0 3.2 2 2 1 3 3 3 0 KAP family P-loop domain AAA_17 PF13207.6 ABX13119.1 - 0.016 15.7 0.0 10 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 ABX13119.1 - 0.017 15.0 0.0 5.9 6.8 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ABX13119.1 - 0.029 13.5 0.1 1.5 7.9 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain SRPRB PF09439.10 ABX13119.1 - 0.034 13.6 0.0 19 4.7 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit SKI PF01202.22 ABX13119.1 - 0.051 13.7 0.0 3.4 7.8 0.0 2.7 3 0 0 3 3 2 0 Shikimate kinase Parvo_NS1 PF01057.17 ABX13119.1 - 0.074 12.1 0.0 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF3418 PF11898.8 ABX13119.1 - 0.082 11.6 0.1 0.3 9.7 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3418) DAP3 PF10236.9 ABX13119.1 - 0.13 11.4 0.0 9.5 5.3 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 dNK PF01712.19 ABX13119.1 - 0.14 11.9 0.0 9.3 6.0 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_19 PF13245.6 ABX13119.1 - 0.27 11.6 1.1 20 5.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain Phage_min_cap2 PF06152.11 ABX13119.1 - 0.85 8.4 5.6 13 4.5 0.4 4.0 5 0 0 5 5 5 0 Phage minor capsid protein 2 DUF1456 PF07308.13 ABX13120.1 - 0.0024 18.2 1.0 0.0089 16.3 1.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1456) UbiA PF01040.18 ABX13121.1 - 4.8e-51 173.5 19.0 6.2e-51 173.1 19.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Copper-bind PF00127.20 ABX13122.1 - 2.3e-16 60.1 1.1 2.7e-09 37.4 0.2 3.1 2 2 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX13122.1 - 1.4e-13 50.8 0.0 2.3e-06 27.7 0.0 2.7 1 1 2 3 3 3 2 Cupredoxin-like domain Prok-JAB PF14464.6 ABX13123.1 - 1.5e-19 69.9 0.0 1.7e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Toxin-JAB1 PF15659.6 ABX13123.1 - 1.3e-05 25.4 0.1 3.3e-05 24.1 0.0 1.5 1 1 1 2 2 2 1 JAB-like toxin 1 JAB PF01398.21 ABX13123.1 - 0.00043 20.3 0.0 0.00061 19.8 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RadC PF04002.15 ABX13123.1 - 0.052 13.5 0.1 0.078 12.9 0.1 1.4 1 1 0 1 1 1 0 RadC-like JAB domain Cyclophil_like PF04126.13 ABX13124.1 - 5.3e-44 148.9 0.0 5.9e-44 148.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 ABX13124.1 - 1.1e-07 31.9 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin-like family YEATS PF03366.16 ABX13124.1 - 0.046 13.7 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 YEATS family DUF2024 PF09630.10 ABX13125.1 - 8e-38 128.2 1.5 8.9e-38 128.0 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) Haem_bd PF14376.6 ABX13125.1 - 0.041 13.8 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Haem-binding domain Ald_deCOase PF11266.8 ABX13125.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase H_PPase PF03030.16 ABX13127.1 - 6.3e-223 742.1 50.8 7.2e-223 741.9 50.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase NEMP PF10225.9 ABX13127.1 - 0.0048 16.6 11.0 0.013 15.2 8.2 2.6 2 0 0 2 2 2 1 NEMP family SprT-like PF10263.9 ABX13128.1 - 0.0017 18.2 0.1 0.0025 17.7 0.1 1.3 1 1 0 1 1 1 1 SprT-like family DUF45 PF01863.17 ABX13128.1 - 0.0073 16.4 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_M76 PF09768.9 ABX13128.1 - 0.041 13.7 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase M76 family DUF359 PF04019.12 ABX13129.1 - 2.4e-37 127.4 0.3 3.1e-37 127.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF359) DRTGG PF07085.12 ABX13129.1 - 0.067 13.0 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 DRTGG domain ParA PF10609.9 ABX13130.1 - 2.7e-99 331.6 0.1 3.5e-99 331.2 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 ABX13130.1 - 5.1e-18 65.0 0.1 2e-17 63.1 0.0 2.0 2 0 0 2 2 1 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 ABX13130.1 - 2.5e-13 50.2 0.0 7.4e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ABX13130.1 - 1e-08 35.3 2.9 1.6e-07 31.5 0.9 2.3 1 1 0 2 2 2 1 AAA domain MipZ PF09140.11 ABX13130.1 - 4.7e-07 29.3 0.0 7.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 ABX13130.1 - 1.8e-06 27.9 1.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain Fer4_NifH PF00142.18 ABX13130.1 - 3.6e-06 26.6 0.1 0.00088 18.8 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 ABX13130.1 - 0.00017 20.9 1.9 0.00033 19.9 0.9 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 ABX13130.1 - 0.00093 18.7 0.0 0.0024 17.4 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ VirC1 PF07015.11 ABX13130.1 - 0.005 16.2 0.0 0.0096 15.2 0.0 1.4 1 0 0 1 1 1 1 VirC1 protein MeaB PF03308.16 ABX13130.1 - 0.0082 15.1 0.2 0.013 14.5 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1610 PF07754.11 ABX13130.1 - 0.025 14.6 0.3 0.045 13.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) SRP54 PF00448.22 ABX13130.1 - 0.041 13.5 0.4 0.46 10.1 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CLP1_P PF16575.5 ABX13130.1 - 0.043 13.6 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 ABX13130.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 ABX13130.1 - 0.09 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 ABX13130.1 - 0.092 12.3 0.7 0.17 11.5 0.7 1.3 1 0 0 1 1 1 0 AAA domain SHS2_Rpb7-N PF03876.17 ABX13131.1 - 6.5e-17 61.7 0.0 1.5e-16 60.5 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 ABX13131.1 - 4.3e-14 52.6 0.0 7.8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.6 ABX13131.1 - 0.012 15.7 0.0 0.028 14.5 0.0 1.6 1 1 0 1 1 1 0 S1 domain BPL_C PF02237.17 ABX13131.1 - 0.031 14.2 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Spt4 PF06093.13 ABX13132.1 - 6.6e-13 48.6 0.6 8.3e-13 48.3 0.6 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RecR PF02132.15 ABX13132.1 - 0.012 15.1 0.6 0.016 14.7 0.6 1.2 1 0 0 1 1 1 0 RecR protein TF_Zn_Ribbon PF08271.12 ABX13132.1 - 0.017 14.6 0.7 0.067 12.7 0.0 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 ABX13132.1 - 0.026 13.9 1.6 1.2 8.7 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Laminin_EGF PF00053.24 ABX13132.1 - 0.034 14.3 0.5 0.046 13.9 0.5 1.2 1 0 0 1 1 1 0 Laminin EGF domain TackOD1 PF18551.1 ABX13132.1 - 0.038 13.7 0.6 0.047 13.4 0.6 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 RNA_POL_M_15KD PF02150.16 ABX13132.1 - 0.27 11.2 0.2 0.27 11.2 0.2 2.0 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit QRPTase_C PF01729.19 ABX13133.1 - 9e-54 181.8 1.0 9e-54 181.8 1.0 1.4 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 ABX13133.1 - 2.3e-25 88.4 0.1 4.1e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.19 ABX13133.1 - 0.0066 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TPR_1 PF00515.28 ABX13134.1 - 9e-15 53.8 2.5 1.5e-05 24.6 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ABX13134.1 - 2.7e-14 52.1 0.6 0.00024 21.0 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ABX13134.1 - 9.2e-12 45.0 3.6 1.2e-09 38.2 0.6 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ABX13134.1 - 4.7e-10 39.8 0.4 2.4e-07 31.2 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ABX13134.1 - 6.5e-09 35.3 3.3 0.00019 21.4 0.0 2.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ABX13134.1 - 2.4e-08 34.5 0.0 1.3e-06 29.0 0.0 2.1 1 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ABX13134.1 - 8.2e-07 29.0 4.2 0.0028 17.7 0.2 3.0 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 ABX13134.1 - 9.3e-07 29.1 0.3 0.04 14.2 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ABX13134.1 - 7e-06 26.1 1.9 0.14 12.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ABX13134.1 - 3e-05 23.7 0.2 0.085 12.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ABX13134.1 - 4.5e-05 23.9 0.0 0.054 14.3 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 ABX13134.1 - 0.00037 20.1 3.4 0.0012 18.5 0.4 2.7 2 1 0 2 2 2 1 TPR repeat TPR_3 PF07720.12 ABX13134.1 - 0.00045 20.1 6.3 0.0019 18.1 0.5 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 ABX13134.1 - 0.00048 20.6 0.1 0.53 11.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 ABX13134.1 - 0.004 17.3 0.0 1.1 9.4 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF4919 PF16266.5 ABX13134.1 - 0.0047 16.9 0.8 0.2 11.6 0.3 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4919) Clathrin PF00637.20 ABX13134.1 - 0.009 15.9 0.4 0.16 11.9 0.4 2.1 1 1 0 1 1 1 1 Region in Clathrin and VPS NadA PF02445.16 ABX13135.1 - 2.8e-114 381.3 4.0 3.2e-114 381.1 4.0 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein ApeC PF16977.5 ABX13135.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of apextrin DUF108 PF01958.18 ABX13136.1 - 1.2e-33 115.3 1.3 1.3e-32 112.0 0.9 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 ABX13136.1 - 6e-15 55.9 0.0 9.7e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 ABX13136.1 - 7.2e-05 22.9 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 ABX13136.1 - 0.00041 20.9 0.3 0.0016 19.0 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 ABX13136.1 - 0.0048 17.3 0.0 0.0084 16.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ABX13136.1 - 0.0058 16.5 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 ABX13136.1 - 0.02 15.7 0.2 0.061 14.1 0.0 1.8 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.15 ABX13136.1 - 0.052 13.7 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NurA PF09376.10 ABX13138.1 - 1.9e-19 70.3 0.0 2.6e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 NurA domain OpuAC PF04069.12 ABX13138.1 - 0.058 13.0 0.0 0.17 11.4 0.0 1.6 1 1 1 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system DUF87 PF01935.17 ABX13139.1 - 2e-36 126.2 3.4 2e-36 126.2 3.4 1.8 2 0 0 2 2 2 1 Helicase HerA, central domain ABC_tran PF00005.27 ABX13139.1 - 0.018 15.6 0.0 0.04 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TrwB_AAD_bind PF10412.9 ABX13139.1 - 0.022 13.7 0.1 0.066 12.1 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Methyltransf_18 PF12847.7 ABX13139.1 - 0.025 14.5 0.4 19 5.2 0.0 3.4 3 0 0 3 3 3 0 Methyltransferase domain AbiH PF14253.6 ABX13139.1 - 0.077 12.9 0.4 0.14 12.0 0.4 1.5 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF4709 PF15821.5 ABX13139.1 - 0.078 13.3 0.6 0.22 11.8 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) AAA_16 PF13191.6 ABX13139.1 - 0.11 12.9 0.0 0.42 11.0 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain Metallophos_2 PF12850.7 ABX13140.1 - 2.8e-09 37.4 0.0 4.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 ABX13140.1 - 1.4e-08 35.5 0.9 2.2e-08 34.8 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Osmo_CC PF08946.10 ABX13140.1 - 0.0074 16.5 1.9 0.19 12.0 0.1 3.1 3 0 0 3 3 3 1 Osmosensory transporter coiled coil DUF211 PF02680.14 ABX13140.1 - 0.14 12.3 1.5 3.9 7.7 0.2 3.1 2 1 1 3 3 3 0 Uncharacterized ArCR, COG1888 AAA_15 PF13175.6 ABX13141.1 - 2.6e-16 60.3 63.3 1.3e-10 41.6 26.1 2.3 1 1 1 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ABX13141.1 - 2.9e-14 54.0 87.2 1.1e-06 29.3 72.8 4.6 1 1 1 2 2 1 1 AAA domain SMC_N PF02463.19 ABX13141.1 - 1e-13 51.3 32.4 4.3e-09 36.1 0.8 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ABX13141.1 - 2e-10 41.0 15.8 2.8e-05 24.1 4.8 3.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABX13141.1 - 4.1e-09 36.0 0.1 8e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 ABX13141.1 - 3.6e-07 30.0 1.4 3.6e-07 30.0 1.4 3.6 3 1 1 4 4 4 1 AAA domain SbcCD_C PF13558.6 ABX13141.1 - 1.7e-05 25.0 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 ABX13141.1 - 0.0088 16.0 0.1 0.0088 16.0 0.1 3.7 3 1 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 ABX13141.1 - 0.009 16.5 0.1 0.009 16.5 0.1 5.4 2 1 1 3 3 2 1 ABC transporter MukB PF04310.12 ABX13141.1 - 0.024 14.5 0.1 0.024 14.5 0.1 3.2 3 2 1 5 5 5 0 MukB N-terminal Fez1 PF06818.15 ABX13141.1 - 0.1 13.0 54.4 2.3 8.7 1.6 4.4 1 1 3 4 4 4 0 Fez1 AAA_13 PF13166.6 ABX13141.1 - 0.78 8.3 67.0 0.077 11.6 12.6 4.3 1 1 3 4 4 4 0 AAA domain RNA_helicase PF00910.22 ABX13141.1 - 1.3 9.4 3.8 8.9 6.8 0.1 3.4 3 1 0 3 3 3 0 RNA helicase BRI3BP PF14965.6 ABX13141.1 - 1.5 8.3 4.9 29 4.1 0.0 3.0 3 0 0 3 3 3 0 Negative regulator of p53/TP53 DEAD PF00270.29 ABX13141.1 - 2.8 7.7 7.3 0.88 9.3 0.1 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase HrpB7 PF09486.10 ABX13141.1 - 4.6 7.6 26.1 0.031 14.6 2.2 3.8 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) AAA_16 PF13191.6 ABX13141.1 - 5.9 7.2 7.3 13 6.1 3.7 3.2 2 1 0 2 2 2 0 AAA ATPase domain BRE1 PF08647.11 ABX13141.1 - 6.6 6.9 58.2 0.14 12.2 16.0 5.1 4 0 0 4 4 4 0 BRE1 E3 ubiquitin ligase MMR_HSR1 PF01926.23 ABX13141.1 - 7.9 6.6 11.7 3.6 7.7 4.7 3.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase ERM PF00769.19 ABX13141.1 - 8.1 6.2 55.1 6.6 6.5 29.4 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.11 ABX13141.1 - 9.8 4.9 64.9 2.4 7.0 2.0 4.5 1 1 4 5 5 5 0 Spc7 kinetochore protein AT_hook PF02178.19 ABX13142.1 - 0.4 10.7 4.7 0.9 9.6 4.7 1.6 1 0 0 1 1 1 0 AT hook motif HATPase_c PF02518.26 ABX13143.1 - 1.2e-15 58.0 0.3 2.5e-15 56.9 0.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 ABX13143.1 - 2.8e-11 43.7 6.4 2.8e-11 43.7 6.4 3.1 2 1 1 3 3 3 1 Cache domain HisKA PF00512.25 ABX13143.1 - 1.1e-09 38.2 0.3 3.8e-09 36.5 0.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 ABX13143.1 - 4.5e-09 36.1 1.5 1.5e-08 34.4 0.7 2.4 2 0 0 2 2 2 1 GHKL domain sCache_3_2 PF17203.4 ABX13143.1 - 1.3e-06 28.5 0.0 7.9e-05 22.8 0.0 2.6 1 1 1 2 2 2 1 Single cache domain 3 YojJ PF10372.9 ABX13143.1 - 0.017 15.2 4.6 1.2 9.3 1.6 2.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DBR1 PF05011.13 ABX13143.1 - 0.042 14.3 0.6 3.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain FlgN PF05130.12 ABX13143.1 - 0.061 13.8 4.2 2.7 8.5 0.7 2.4 2 0 0 2 2 2 0 FlgN protein BAR_3_WASP_bdg PF10456.9 ABX13143.1 - 0.13 11.7 1.3 0.3 10.5 0.2 1.9 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein DUF4446 PF14584.6 ABX13143.1 - 0.24 11.4 7.9 0.4 10.7 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) PepSY_TM PF03929.16 ABX13143.1 - 0.33 10.6 0.7 0.69 9.5 0.7 1.5 1 0 0 1 1 1 0 PepSY-associated TM region ING PF12998.7 ABX13143.1 - 1.4 9.6 7.3 5.3 7.7 1.4 3.5 2 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF2935 PF11155.8 ABX13143.1 - 2.6 8.4 7.5 12 6.2 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) DUF948 PF06103.11 ABX13143.1 - 7.4 6.9 7.5 0.59 10.4 0.9 2.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Response_reg PF00072.24 ABX13144.1 - 6.9e-17 61.6 0.1 7.7e-17 61.5 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Trypan_PARP PF05887.11 ABX13146.1 - 2.6e-13 50.1 38.2 5e-13 49.2 38.2 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Kazal_1 PF00050.21 ABX13146.1 - 3.4e-10 39.8 0.4 1.5e-09 37.7 0.5 2.0 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 ABX13146.1 - 1.3e-06 28.4 0.4 2.5e-06 27.5 0.4 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Copper-bind PF00127.20 ABX13146.1 - 6.5e-06 26.5 0.5 1.6e-05 25.3 0.5 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX13146.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.5 1 1 0 1 1 1 1 Cupredoxin-like domain Cys_Knot_tox PF17486.2 ABX13146.1 - 0.11 12.8 1.3 45 4.4 0.0 3.0 2 1 1 3 3 3 0 Cystine knot toxins FAM75 PF14650.6 ABX13146.1 - 8.3 5.8 13.5 15 5.0 13.5 1.4 1 1 0 1 1 1 0 FAM75 family HEAT_2 PF13646.6 ABX13147.1 - 3e-20 72.4 0.0 7.6e-10 39.1 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 ABX13147.1 - 2.7e-14 52.0 0.0 0.0045 17.1 0.0 4.2 4 0 0 4 4 4 3 HEAT repeat HEAT_PBS PF03130.16 ABX13147.1 - 2.9e-12 46.0 0.0 0.00036 20.9 0.1 3.6 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 ABX13147.1 - 9.2e-10 38.8 0.0 0.18 12.3 0.0 4.0 4 0 0 4 4 4 3 HEAT-like repeat Cnd1 PF12717.7 ABX13147.1 - 6.2e-07 29.6 0.3 3.6e-05 23.9 0.0 2.7 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ABX13147.1 - 0.00076 18.2 0.1 0.004 15.8 0.0 1.8 1 1 0 2 2 2 1 Adaptin N terminal region Arm PF00514.23 ABX13147.1 - 0.0012 18.8 0.0 1 9.5 0.0 3.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF2019 PF09450.10 ABX13147.1 - 0.0042 17.0 0.1 0.74 9.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2019) V-ATPase_H_N PF03224.14 ABX13147.1 - 0.14 11.4 0.0 0.38 10.0 0.0 1.7 2 0 0 2 2 2 0 V-ATPase subunit H Redoxin PF08534.10 ABX13148.1 - 2.4e-07 30.5 0.0 0.0001 22.0 0.0 2.2 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 ABX13148.1 - 1.2e-06 28.5 0.1 2.4e-05 24.2 0.1 2.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 ABX13148.1 - 0.0055 17.0 0.0 0.61 10.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.6 ABX13148.1 - 0.013 15.7 0.0 0.038 14.1 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 ABX13148.1 - 0.017 15.5 0.3 0.14 12.6 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain GSHPx PF00255.19 ABX13148.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione peroxidase Ribosomal_L15e PF00827.17 ABX13150.1 - 4.2e-45 153.8 3.8 5.1e-45 153.6 3.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 CLIP_1 PF18322.1 ABX13153.1 - 0.044 13.9 1.1 0.71 10.0 0.3 2.3 2 0 0 2 2 2 0 Serine protease Clip domain PPAF-2 2-Hacid_dh_C PF02826.19 ABX13154.1 - 1.7e-60 203.4 0.2 3.4e-60 202.4 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ABX13154.1 - 2e-30 105.2 0.3 2.2e-30 105.0 0.3 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ABX13154.1 - 0.0013 18.9 0.4 0.008 16.4 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase LXG PF04740.12 ABX13154.1 - 0.0038 17.0 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 LXG domain of WXG superfamily Cu-oxidase_3 PF07732.15 ABX13155.1 - 2.4e-09 37.2 0.8 6.2e-08 32.7 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ABX13155.1 - 0.23 11.2 1.6 12 5.7 0.1 2.8 2 1 0 2 2 2 0 Multicopper oxidase Lyase_1 PF00206.20 ABX13156.1 - 1.7e-87 293.8 0.7 2.4e-87 293.3 0.7 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 ABX13156.1 - 2.8e-14 53.3 0.0 6.2e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Radical_SAM PF04055.21 ABX13157.1 - 3.1e-20 73.2 0.1 4.7e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 ABX13157.1 - 4.5e-17 61.9 1.1 5.8e-17 61.6 0.1 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 zf-PARP PF00645.18 ABX13157.1 - 0.0046 17.8 0.3 0.015 16.1 0.3 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region TRAM PF01938.20 ABX13157.1 - 0.0051 16.8 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 ABX13157.1 - 0.031 14.5 0.1 0.21 11.8 0.0 2.4 2 1 0 2 2 2 0 TRAM domain Tubulin PF00091.25 ABX13158.1 - 3.9e-16 59.8 0.3 2.3e-14 54.1 0.1 2.4 1 1 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Ribosomal_L31e PF01198.19 ABX13159.1 - 5.9e-17 61.7 0.3 1.2e-16 60.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L31e DUF4045 PF13254.6 ABX13159.1 - 1.4 8.5 22.7 1.5 8.4 22.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RR_TM4-6 PF06459.12 ABX13159.1 - 2.6 7.8 21.9 2.7 7.7 21.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.11 ABX13159.1 - 4.4 7.3 30.0 5.2 7.1 30.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_L39 PF00832.20 ABX13160.1 - 9.3e-19 66.8 6.6 1.1e-18 66.6 6.6 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein REV PF00424.18 ABX13160.1 - 0.054 13.5 0.7 0.061 13.4 0.7 1.1 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Ter PF05472.11 ABX13160.1 - 0.15 11.1 1.4 0.16 11.0 1.4 1.0 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) NUDIX PF00293.28 ABX13161.1 - 1.7e-11 44.3 0.0 2.4e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MTHFR PF02219.17 ABX13162.1 - 1.8e-05 24.3 0.0 3e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF2935 PF11155.8 ABX13162.1 - 0.026 14.9 0.1 0.82 10.0 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) Pterin_bind PF00809.22 ABX13163.1 - 1.9e-29 103.0 0.0 2.8e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme Met_synt_B12 PF02965.17 ABX13163.1 - 1.9e-24 86.6 0.0 7.2e-24 84.7 0.0 1.9 1 1 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding_2 PF02607.17 ABX13163.1 - 2.7e-19 69.4 0.0 8.6e-19 67.8 0.0 1.9 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 ABX13163.1 - 9.3e-18 64.4 0.0 2.1e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain CdhD PF03599.16 ABX13163.1 - 0.0052 15.6 0.0 0.0098 14.6 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit adh_short PF00106.25 ABX13163.1 - 0.021 14.3 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase S-methyl_trans PF02574.16 ABX13164.1 - 3e-62 210.8 0.0 3.5e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase MFS_1 PF07690.16 ABX13165.1 - 7.3e-26 90.9 46.2 1.1e-24 87.1 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ABX13165.1 - 0.013 14.3 29.2 0.1 11.4 27.9 2.6 1 1 0 1 1 1 0 MFS_1 like family DUF4094 PF13334.6 ABX13165.1 - 0.072 13.5 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF4508 PF14969.6 ABX13166.1 - 0.017 15.4 0.5 0.61 10.4 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4508) CBS PF00571.28 ABX13167.1 - 5.3e-33 113.2 0.7 3.3e-08 33.9 0.1 4.2 4 0 0 4 4 4 4 CBS domain PBP_dimer PF03717.15 ABX13167.1 - 0.041 14.2 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain DUF2497 PF10691.9 ABX13167.1 - 0.079 13.4 1.3 7.2 7.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2497) Usp PF00582.26 ABX13168.1 - 1.5e-23 83.9 0.0 1.9e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Caerin_1 PF07440.12 ABX13168.1 - 0.13 12.4 0.4 21 5.3 0.2 2.4 2 0 0 2 2 2 0 Caerin 1 protein Copper-bind PF00127.20 ABX13169.1 - 0.00041 20.8 0.3 0.0018 18.7 0.0 2.2 2 1 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX13169.1 - 0.00083 19.4 0.0 0.0034 17.5 0.0 2.1 2 1 0 2 2 2 1 Cupredoxin-like domain PKD PF00801.20 ABX13169.1 - 0.33 10.8 1.6 1.9 8.4 0.4 2.7 2 2 1 3 3 3 0 PKD domain Usp PF00582.26 ABX13170.1 - 1.2e-32 113.4 0.0 1.3e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family GARS_N PF02844.15 ABX13170.1 - 0.11 13.3 0.1 0.18 12.6 0.1 1.6 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Rhodanese PF00581.20 ABX13171.1 - 2.2e-21 76.4 0.0 5.6e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain HTH_24 PF13412.6 ABX13172.1 - 6e-16 57.7 0.0 1.3e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABX13172.1 - 2.3e-07 30.6 0.2 0.0021 17.9 0.1 2.2 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 ABX13172.1 - 1.4e-06 28.6 0.3 0.03 14.6 0.0 2.2 2 0 0 2 2 2 2 Penicillinase repressor MarR PF01047.22 ABX13172.1 - 1.8e-05 24.6 0.0 0.031 14.2 0.0 2.2 2 0 0 2 2 2 2 MarR family HTH_5 PF01022.20 ABX13172.1 - 2.9e-05 23.9 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 ABX13172.1 - 0.00012 21.8 0.0 0.041 13.8 0.0 2.2 2 0 0 2 2 2 2 MarR family Fe_dep_repress PF01325.19 ABX13172.1 - 0.0099 16.1 0.1 0.71 10.1 0.0 2.5 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_27 PF13463.6 ABX13172.1 - 0.01 16.3 0.1 1.5 9.4 0.0 2.6 2 2 0 2 2 2 0 Winged helix DNA-binding domain GPP34 PF05719.11 ABX13172.1 - 0.059 13.4 0.0 0.18 11.8 0.0 1.6 1 1 1 2 2 2 0 Golgi phosphoprotein 3 (GPP34) Mnd1 PF03962.15 ABX13172.1 - 0.082 13.2 1.8 6.4 7.1 0.0 3.2 2 2 1 3 3 3 0 Mnd1 HTH domain DrsE PF02635.15 ABX13173.1 - 7.3e-08 32.8 0.0 1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE_2 PF13686.6 ABX13173.1 - 0.046 13.6 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family HTH_24 PF13412.6 ABX13177.1 - 1.3e-14 53.4 2.3 1.1e-06 28.0 0.1 2.6 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ABX13177.1 - 7.8e-09 35.3 0.0 0.00013 21.8 0.0 2.4 2 0 0 2 2 2 2 MarR family HTH_5 PF01022.20 ABX13177.1 - 3.1e-08 33.4 0.3 5.3e-06 26.2 0.1 2.4 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family HTH_34 PF13601.6 ABX13177.1 - 2.2e-07 30.9 2.2 0.0028 17.8 0.5 2.2 2 0 0 2 2 2 2 Winged helix DNA-binding domain MarR PF01047.22 ABX13177.1 - 6.4e-07 29.2 0.7 0.013 15.4 0.0 2.8 3 0 0 3 3 3 2 MarR family HTH_20 PF12840.7 ABX13177.1 - 2.3e-05 24.3 0.0 0.023 14.7 0.0 2.1 2 0 0 2 2 2 2 Helix-turn-helix domain TrmB PF01978.19 ABX13177.1 - 0.00012 21.9 1.0 0.25 11.2 0.4 2.3 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ABX13177.1 - 0.014 15.1 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain DprA_WH PF17782.1 ABX13177.1 - 0.023 14.8 0.0 7.2 6.8 0.0 2.2 2 0 0 2 2 2 0 DprA winged helix domain BPD_transp_1 PF00528.22 ABX13179.1 - 1.6e-22 80.2 15.0 2.7e-22 79.4 15.0 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 ABX13180.1 - 2.3e-31 109.1 0.0 4.1e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABX13180.1 - 1.2e-09 38.4 0.0 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 ABX13180.1 - 0.00072 20.0 0.2 0.01 16.2 0.2 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 ABX13180.1 - 0.002 17.9 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ABX13180.1 - 0.0049 16.6 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ABX13180.1 - 0.0057 16.4 0.0 0.54 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ABX13180.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 ABX13180.1 - 0.012 15.9 0.1 0.041 14.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 ABX13180.1 - 0.018 14.5 0.2 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 ABX13180.1 - 0.019 14.9 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 ABX13180.1 - 0.027 14.5 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ABX13180.1 - 0.032 14.6 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 ABX13180.1 - 0.044 13.7 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 ABX13180.1 - 0.067 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ABX13180.1 - 0.068 13.1 0.0 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 ABX13180.1 - 0.077 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ABX13180.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ABX13180.1 - 0.096 13.1 0.0 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 ABX13180.1 - 0.1 12.3 0.1 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 ABX13180.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain VASP_tetra PF08776.11 ABX13180.1 - 0.15 11.7 0.4 0.28 10.8 0.4 1.5 1 0 0 1 1 1 0 VASP tetramerisation domain NMT1_2 PF13379.6 ABX13181.1 - 3.4e-28 99.0 0.0 4.8e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 ABX13181.1 - 1.4e-12 48.0 0.0 2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 ABX13181.1 - 5.2e-09 36.1 0.0 1.6e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 ABX13181.1 - 0.00036 20.0 0.0 0.39 10.1 0.0 2.9 2 1 1 3 3 3 2 Bacterial extracellular solute-binding proteins, family 3 Pep_deformylase PF01327.21 ABX13181.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase NMT1_3 PF16868.5 ABX13181.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family Arginosuc_synth PF00764.19 ABX13182.1 - 2.9e-158 527.2 0.2 3.4e-158 527.0 0.2 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.21 ABX13182.1 - 4.5e-05 23.3 0.0 7.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 ABX13182.1 - 0.00033 20.2 0.0 0.00061 19.3 0.0 1.5 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Flagellin_IN PF07196.13 ABX13182.1 - 0.082 13.1 0.8 14 6.0 0.1 2.7 2 0 0 2 2 2 0 Flagellin hook IN motif zinc_ribbon_4 PF13717.6 ABX13183.1 - 6.5e-06 26.0 0.4 0.033 14.1 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.6 ABX13183.1 - 3.9e-05 23.3 0.2 0.023 14.5 0.0 2.1 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 ABX13183.1 - 0.00035 20.0 0.9 0.00052 19.5 0.9 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding zf-TFIIB PF13453.6 ABX13183.1 - 0.0005 19.3 0.4 0.21 11.0 0.1 2.1 2 0 0 2 2 2 2 Transcription factor zinc-finger zf-ribbon_3 PF13248.6 ABX13183.1 - 0.0005 19.4 1.0 0.48 9.9 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain UPF0547 PF10571.9 ABX13183.1 - 0.00075 19.5 2.4 0.17 12.0 0.2 2.2 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 zf-RING_7 PF02591.15 ABX13183.1 - 0.0026 17.9 1.5 0.089 13.0 0.1 2.4 2 0 0 2 2 2 1 C4-type zinc ribbon domain RNA_POL_M_15KD PF02150.16 ABX13183.1 - 0.006 16.4 0.3 0.0096 15.8 0.3 1.3 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit HypA PF01155.19 ABX13183.1 - 0.0067 16.4 0.3 0.0074 16.3 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C4_Topoisom PF01396.19 ABX13183.1 - 0.0075 16.0 1.1 1.8 8.4 0.0 2.2 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger YacG PF03884.14 ABX13183.1 - 0.009 15.7 0.5 1.3 8.8 0.0 2.2 2 0 0 2 2 2 1 DNA gyrase inhibitor YacG zf_UBZ PF18439.1 ABX13183.1 - 0.011 15.3 1.3 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger A2L_zn_ribbon PF08792.10 ABX13183.1 - 0.016 14.9 1.6 2 8.2 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc-ribbons_6 PF07191.12 ABX13183.1 - 0.016 15.2 0.6 0.059 13.4 0.6 1.8 1 1 0 1 1 1 0 zinc-ribbons zf-HYPF PF07503.12 ABX13183.1 - 0.019 14.7 1.5 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 HypF finger DNA_RNApol_7kD PF03604.13 ABX13183.1 - 0.022 14.4 3.1 1.1 9.0 2.2 2.8 1 1 2 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 ABX13183.1 - 0.024 14.7 0.4 0.037 14.1 0.4 1.4 1 1 0 1 1 1 0 Double zinc ribbon DNA_ligase_ZBD PF03119.16 ABX13183.1 - 0.024 14.6 3.1 3.6 7.7 0.1 2.6 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn_Tnp_IS1 PF03811.13 ABX13183.1 - 0.025 14.3 0.3 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 InsA N-terminal domain CpXC PF14353.6 ABX13183.1 - 0.031 14.3 0.3 1.8 8.6 0.0 2.1 2 0 0 2 2 2 0 CpXC protein Ogr_Delta PF04606.12 ABX13183.1 - 0.033 14.2 0.4 4.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Prok-RING_1 PF14446.6 ABX13183.1 - 0.033 14.1 5.2 0.057 13.4 5.2 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 ABX13183.1 - 0.042 14.0 3.7 0.65 10.2 0.2 2.1 1 1 0 2 2 2 0 Zinc ribbon domain Lar_restr_allev PF14354.6 ABX13183.1 - 0.043 14.2 1.4 0.061 13.7 1.4 1.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar PhnA_Zn_Ribbon PF08274.12 ABX13183.1 - 0.045 13.7 2.4 0.56 10.2 2.8 2.1 1 1 1 2 2 2 0 PhnA Zinc-Ribbon zinc_ribbon_9 PF14369.6 ABX13183.1 - 0.046 14.0 4.2 0.16 12.3 4.2 1.7 1 1 0 1 1 1 0 zinc-ribbon IBR PF01485.21 ABX13183.1 - 0.076 13.3 0.3 0.096 12.9 0.3 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Anti-TRAP PF15777.5 ABX13183.1 - 0.12 12.3 1.9 0.27 11.2 1.9 1.6 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-ACC PF17848.1 ABX13183.1 - 0.12 12.4 3.0 4.7 7.4 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-IS66 PF13005.7 ABX13183.1 - 0.15 12.5 2.5 2.9 8.3 0.2 2.2 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 DUF1451 PF07295.11 ABX13183.1 - 0.16 12.0 0.3 0.25 11.4 0.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain PADR1 PF08063.12 ABX13183.1 - 0.47 10.3 3.2 1.6 8.6 0.1 2.1 1 1 1 2 2 2 0 PADR1 (NUC008) domain DUF983 PF06170.12 ABX13183.1 - 1.1 9.7 2.9 2.8 8.4 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Rubredoxin PF00301.20 ABX13183.1 - 2 8.5 6.0 7.6 6.6 0.7 2.4 1 1 1 2 2 2 0 Rubredoxin RimK PF08443.11 ABX13184.1 - 9.3e-29 100.4 0.0 1.2e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 ABX13184.1 - 1.4e-10 40.9 0.1 7.7e-06 25.4 0.0 2.7 2 1 0 3 3 3 2 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 ABX13184.1 - 6.5e-09 35.4 0.0 8.7e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 ABX13184.1 - 4.1e-08 33.4 0.0 1.4e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 ABX13184.1 - 9.3e-07 28.6 0.0 1.1e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 ABX13184.1 - 9.1e-06 25.1 0.0 0.09 12.0 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp GARS_A PF01071.19 ABX13184.1 - 0.00039 20.2 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Dala_Dala_lig_C PF07478.13 ABX13184.1 - 0.00054 19.5 0.0 0.086 12.4 0.0 2.2 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 ABX13184.1 - 0.00064 19.3 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 ABX13184.1 - 0.001 18.7 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 ABX13184.1 - 0.0094 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Semialdhyde_dh PF01118.24 ABX13185.1 - 6.9e-36 123.3 0.0 1.1e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 ABX13185.1 - 7.2e-17 62.1 0.0 1.1e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Sacchrp_dh_NADP PF03435.18 ABX13185.1 - 5.2e-05 23.5 0.0 9.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 ABX13185.1 - 0.0003 21.6 0.0 0.00054 20.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 ABX13185.1 - 0.00096 19.3 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 ABX13185.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AA_kinase PF00696.28 ABX13186.1 - 5.2e-40 137.6 3.0 5.8e-40 137.4 3.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family MAF_flag10 PF01973.18 ABX13186.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 DUF4947 PF16305.5 ABX13186.1 - 0.068 13.2 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4947) Ribosomal_L21p PF00829.21 ABX13186.1 - 0.083 13.2 2.0 0.94 9.8 0.6 2.4 2 1 0 2 2 2 0 Ribosomal prokaryotic L21 protein Aminotran_3 PF00202.21 ABX13187.1 - 6.7e-116 387.3 0.1 8.3e-116 387.0 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ABX13187.1 - 5.2e-05 22.6 0.0 0.00012 21.4 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ABX13187.1 - 0.056 12.4 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V DUF2931 PF11153.8 ABX13187.1 - 0.06 13.0 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) HTH_AsnC-type PF13404.6 ABX13188.1 - 2.7e-12 46.3 0.0 5.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 ABX13188.1 - 1.7e-11 43.9 0.2 2.4e-11 43.4 0.2 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 ABX13188.1 - 6.8e-10 38.4 0.2 1.1e-09 37.7 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding NapD PF03927.13 ABX13188.1 - 0.003 17.6 0.8 0.0056 16.7 0.8 1.5 1 0 0 1 1 1 1 NapD protein Mga PF05043.13 ABX13188.1 - 0.009 16.6 0.0 0.016 15.8 0.0 1.4 1 0 0 1 1 1 1 Mga helix-turn-helix domain HTH_11 PF08279.12 ABX13188.1 - 0.0095 15.9 0.5 0.019 14.9 0.1 1.8 2 0 0 2 2 2 1 HTH domain Sigma70_r4 PF04545.16 ABX13188.1 - 0.014 14.9 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 ACT_4 PF13291.6 ABX13188.1 - 0.018 15.6 0.3 3.3 8.4 0.1 2.2 2 0 0 2 2 2 0 ACT domain MarR PF01047.22 ABX13188.1 - 0.044 13.7 0.3 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 MarR family FeoC PF09012.10 ABX13188.1 - 0.05 13.7 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_9 PF08221.11 ABX13188.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_5 PF01022.20 ABX13188.1 - 0.063 13.2 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 ABX13188.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 MarR family DDRGK PF09756.9 ABX13188.1 - 0.075 12.6 0.8 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 DDRGK domain SCO1-SenC PF02630.14 ABX13188.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC HTH_Tnp_ISL3 PF13542.6 ABX13188.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HMGL-like PF00682.19 ABX13189.1 - 3.5e-67 226.7 0.0 4.9e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Radical_SAM PF04055.21 ABX13189.1 - 0.17 12.3 0.2 0.73 10.2 0.0 2.0 2 1 0 2 2 2 0 Radical SAM superfamily zinc_ribbon_4 PF13717.6 ABX13190.1 - 1.3e-06 28.2 3.3 0.0015 18.4 1.0 2.0 1 1 1 2 2 2 2 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 ABX13190.1 - 7.7e-05 22.6 6.6 0.0019 18.1 3.3 1.9 1 1 1 2 2 2 2 PhnA Zinc-Ribbon zf-RING_7 PF02591.15 ABX13190.1 - 0.00013 22.0 0.9 0.0035 17.5 0.1 2.2 2 0 0 2 2 2 1 C4-type zinc ribbon domain zf_UBZ PF18439.1 ABX13190.1 - 0.00098 18.7 1.8 0.32 10.6 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zinc_ribbon_5 PF13719.6 ABX13190.1 - 0.0015 18.3 0.3 0.11 12.3 0.0 2.1 2 0 0 2 2 2 1 zinc-ribbon domain Prok-RING_1 PF14446.6 ABX13190.1 - 0.0019 18.1 2.8 0.0033 17.3 2.8 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 ABX13190.1 - 0.0025 17.9 1.4 0.0042 17.2 1.4 1.4 1 0 0 1 1 1 1 Zinc ribbon domain zf-C4_Topoisom PF01396.19 ABX13190.1 - 0.0032 17.2 0.8 0.4 10.5 0.0 2.1 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 ABX13190.1 - 0.0043 17.3 1.1 0.0061 16.8 1.1 1.2 1 0 0 1 1 1 1 zinc-ribbon BssC_TutF PF08201.11 ABX13190.1 - 0.006 16.6 0.4 0.14 12.2 0.1 2.0 2 0 0 2 2 2 1 BssC/TutF protein zf-ribbon_3 PF13248.6 ABX13190.1 - 0.0068 15.8 0.6 0.13 11.7 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain HypA PF01155.19 ABX13190.1 - 0.0081 16.2 0.2 0.0085 16.1 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-HYPF PF07503.12 ABX13190.1 - 0.013 15.2 1.9 0.087 12.6 1.9 1.9 1 1 0 1 1 1 0 HypF finger DNA_RNApol_7kD PF03604.13 ABX13190.1 - 0.014 15.0 2.4 0.043 13.5 2.4 1.7 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 ABX13190.1 - 0.017 15.1 0.4 0.025 14.6 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.9 ABX13190.1 - 0.059 13.5 3.1 1.5 8.9 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 ADK_lid PF05191.14 ABX13190.1 - 0.06 13.3 0.3 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid CpXC PF14353.6 ABX13190.1 - 0.075 13.1 1.1 0.83 9.7 0.1 2.0 1 1 1 2 2 2 0 CpXC protein A2L_zn_ribbon PF08792.10 ABX13190.1 - 0.083 12.6 3.1 0.56 10.0 3.1 2.0 1 1 0 1 1 1 0 A2L zinc ribbon domain DUF983 PF06170.12 ABX13190.1 - 0.12 12.7 0.5 4.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zf-C2H2 PF00096.26 ABX13190.1 - 0.24 11.9 0.5 3.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-ACC PF17848.1 ABX13190.1 - 0.44 10.7 5.0 6.1 7.0 0.4 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain PADR1 PF08063.12 ABX13190.1 - 0.65 9.8 3.3 1.9 8.3 0.1 2.1 1 1 1 2 2 2 0 PADR1 (NUC008) domain zf-H2C2_2 PF13465.6 ABX13190.1 - 0.81 10.2 2.6 2.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 ABX13190.1 - 0.85 9.7 0.2 0.85 9.7 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1272 PF06906.11 ABX13190.1 - 0.98 9.6 4.8 2.4 8.3 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) RimK PF08443.11 ABX13191.1 - 4.6e-28 98.1 0.0 6.2e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 ABX13191.1 - 5.8e-09 36.2 0.1 8.8e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 ATP-grasp domain GSH-S_ATP PF02955.16 ABX13191.1 - 3.1e-06 26.7 0.0 4.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 ABX13191.1 - 3.7e-06 26.4 0.1 0.019 14.2 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp PF02222.22 ABX13191.1 - 0.00032 20.3 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 ABX13191.1 - 0.00044 19.8 0.0 0.0013 18.2 0.0 1.8 1 1 1 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_5 PF13549.6 ABX13191.1 - 0.015 14.8 0.0 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Peptidase_M20 PF01546.28 ABX13192.1 - 3.3e-28 98.8 0.2 7.3e-28 97.7 0.2 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ABX13192.1 - 4.4e-14 52.3 0.2 1.1e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 ABX13192.1 - 4.9e-05 22.5 0.7 0.081 11.9 0.1 2.4 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase Big_3 PF07523.12 ABX13192.1 - 0.033 14.5 0.1 0.094 13.0 0.1 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) TP_methylase PF00590.20 ABX13193.1 - 1.6e-19 70.7 0.0 8.2e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF357 PF04010.13 ABX13193.1 - 4.3e-14 52.3 0.1 1.5e-13 50.6 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF357) Alba PF01918.21 ABX13193.1 - 0.068 13.0 0.0 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Alba Ala_racemase_C PF00842.21 ABX13193.1 - 0.093 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain DUF1409 PF07197.12 ABX13193.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) CTP_transf_like PF01467.26 ABX13194.1 - 3.8e-14 53.1 0.0 6.9e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 ABX13194.1 - 0.019 14.9 0.3 0.035 14.0 0.3 1.6 1 1 0 1 1 1 0 FAD synthetase HTH_27 PF13463.6 ABX13194.1 - 0.019 15.5 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain Urm1 PF09138.11 ABX13194.1 - 0.057 13.8 0.3 0.22 11.9 0.1 1.9 1 1 1 2 2 2 0 Urm1 (Ubiquitin related modifier) Glyco_tran_WecB PF03808.13 ABX13194.1 - 0.063 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Met_synt_B12 PF02965.17 ABX13194.1 - 0.12 11.8 0.1 0.15 11.5 0.1 1.1 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain Cullin_Nedd8 PF10557.9 ABX13194.1 - 0.2 11.7 2.7 1 9.5 0.6 2.3 2 0 0 2 2 2 0 Cullin protein neddylation domain HATPase_c PF02518.26 ABX13195.1 - 1.4e-18 67.5 0.9 1.4e-18 67.5 0.9 2.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 ABX13195.1 - 2.4e-16 59.9 0.1 9.7e-16 57.9 0.1 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ABX13195.1 - 5.7e-10 39.2 0.0 1.8e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 ABX13195.1 - 1.5e-09 38.0 0.0 1.8e-08 34.6 0.0 2.4 1 1 1 2 2 2 1 PAS fold HisKA PF00512.25 ABX13195.1 - 2.4e-09 37.1 1.3 6.9e-09 35.6 0.3 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 ABX13195.1 - 3.9e-08 33.1 0.3 1.7e-07 31.1 0.3 2.1 1 0 0 1 1 1 1 GHKL domain HAMP PF00672.25 ABX13195.1 - 1.4e-06 28.5 0.0 3.8e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 HAMP domain PAS_4 PF08448.10 ABX13195.1 - 6.9e-05 23.1 0.0 0.00019 21.7 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 ABX13195.1 - 0.0011 18.9 0.0 0.003 17.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain 4HB_MCP_1 PF12729.7 ABX13195.1 - 0.0011 18.5 0.2 0.0011 18.5 0.2 4.1 4 0 0 4 4 4 2 Four helix bundle sensory module for signal transduction HATPase_c_3 PF13589.6 ABX13195.1 - 0.0026 17.6 0.1 0.0062 16.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABX13195.1 - 0.0082 16.1 0.0 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain BORCS8 PF10167.9 ABX13195.1 - 0.033 14.1 0.8 0.095 12.6 0.8 1.8 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 Usp PF00582.26 ABX13196.1 - 6.4e-05 23.5 0.0 7.1e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family CTP-dep_RFKase PF01982.16 ABX13197.1 - 6e-42 142.6 0.0 8.7e-42 142.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF120 MarR PF01047.22 ABX13197.1 - 0.014 15.3 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 MarR family Phage_rep_O PF04492.13 ABX13197.1 - 0.033 14.8 1.7 1.4 9.6 0.1 2.4 2 1 0 2 2 2 0 Bacteriophage replication protein O HicB PF05534.12 ABX13197.1 - 0.16 11.9 0.0 0.78 9.6 0.0 2.1 2 0 0 2 2 2 0 HicB family Toprim_4 PF13662.6 ABX13198.1 - 1.6e-07 31.7 0.2 3.7e-07 30.5 0.2 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 ABX13198.1 - 6.9e-06 26.4 0.0 1.7e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Toprim-like Fe-S_biosyn PF01521.20 ABX13199.1 - 3.9e-24 85.0 0.0 4.4e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis UPF0181 PF03701.14 ABX13199.1 - 0.12 12.1 0.1 1.9 8.2 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0181) CBS PF00571.28 ABX13200.1 - 4.3e-27 94.3 3.2 5.3e-13 49.2 0.2 2.2 2 0 0 2 2 2 2 CBS domain DUF4964 PF16334.5 ABX13200.1 - 0.035 13.7 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) CopG_antitoxin PF12441.8 ABX13201.1 - 0.00022 21.7 0.3 0.0005 20.6 0.3 1.6 1 0 0 1 1 1 1 CopG antitoxin of type II toxin-antitoxin system HicB PF05534.12 ABX13201.1 - 0.0072 16.1 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 HicB family HTH_20 PF12840.7 ABX13202.1 - 0.00029 20.8 0.0 0.00041 20.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain FUR PF01475.19 ABX13202.1 - 0.0006 19.9 0.1 0.00074 19.7 0.1 1.2 1 0 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.19 ABX13202.1 - 0.0034 17.2 0.1 0.0078 16.1 0.1 1.7 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ABX13202.1 - 0.044 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain RP-C PF03428.13 ABX13202.1 - 0.097 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Replication protein C N-terminal domain Copper-bind PF00127.20 ABX13203.1 - 1.8e-07 31.5 0.0 4.9e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX13203.1 - 4.2e-05 23.6 0.0 7.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Cupredoxin-like domain ECH_1 PF00378.20 ABX13204.1 - 7.7e-68 228.5 1.2 8.6e-68 228.3 1.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABX13204.1 - 2.2e-39 135.9 0.4 2.7e-36 125.7 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ATP-grasp_5 PF13549.6 ABX13205.1 - 7.3e-66 221.8 0.5 1.2e-65 221.1 0.5 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 ABX13205.1 - 7.5e-49 165.1 0.1 2e-48 163.7 0.1 1.8 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ABX13205.1 - 1.1e-27 96.8 0.1 4.2e-27 94.9 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.19 ABX13205.1 - 1.4e-09 38.5 0.2 2.8e-08 34.3 0.0 3.2 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.10 ABX13205.1 - 5.4e-08 32.6 0.7 1.2e-07 31.5 0.7 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 ABX13205.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain TPP_enzyme_M PF00205.22 ABX13205.1 - 0.035 13.8 2.8 0.14 11.9 0.0 3.1 4 0 0 4 4 4 0 Thiamine pyrophosphate enzyme, central domain GATase PF00117.28 ABX13206.1 - 3.1e-22 79.3 0.0 4.5e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ABX13206.1 - 9.5e-09 35.3 0.0 2.4e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase C26 GATase_3 PF07685.14 ABX13206.1 - 0.0042 16.7 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 ABX13206.1 - 0.027 14.3 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family TRADD_N PF09034.10 ABX13206.1 - 0.029 14.4 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain INTS5_N PF14837.6 ABX13206.1 - 0.082 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Toprim_4 PF13662.6 ABX13207.1 - 1e-05 25.9 0.0 0.00031 21.2 0.0 2.2 1 1 0 1 1 1 1 Toprim domain Toprim PF01751.22 ABX13207.1 - 9.6e-05 22.6 0.1 0.0013 18.9 0.1 2.1 1 1 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 ABX13207.1 - 0.0025 18.2 0.0 0.0034 17.8 0.0 1.3 1 1 0 1 1 1 1 Toprim-like ELFV_dehydrog PF00208.21 ABX13208.1 - 4.3e-68 229.6 2.0 6.1e-68 229.1 2.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 ABX13208.1 - 8.7e-49 164.7 0.0 1.7e-48 163.7 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain HTH_17 PF12728.7 ABX13208.1 - 0.011 15.9 0.1 1.9 8.8 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain 2-Hacid_dh_C PF02826.19 ABX13208.1 - 0.11 11.8 0.1 0.24 10.8 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XAP5 PF04921.14 ABX13208.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator HTH_5 PF01022.20 ABX13209.1 - 7.1e-11 41.8 0.4 1.8e-10 40.5 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABX13209.1 - 0.0074 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_45 PF14947.6 ABX13209.1 - 0.0097 15.9 0.3 0.024 14.6 0.3 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix Phage_rep_org_N PF09681.10 ABX13209.1 - 0.016 15.1 1.1 0.016 15.1 1.1 1.3 1 1 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) TrmB PF01978.19 ABX13209.1 - 0.032 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_12 PF08461.10 ABX13209.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_24 PF13412.6 ABX13209.1 - 0.081 12.5 0.1 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding B-block_TFIIIC PF04182.12 ABX13209.1 - 0.085 13.0 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Proteasome PF00227.26 ABX13210.1 - 5.4e-49 166.3 2.5 7e-49 165.9 2.5 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ABX13210.1 - 2e-12 46.5 1.7 1.3e-10 40.8 0.2 2.6 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature Ubie_methyltran PF01209.18 ABX13211.1 - 6e-18 65.0 0.0 7.3e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ABX13211.1 - 3e-13 50.2 0.0 4.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX13211.1 - 1.9e-11 44.5 0.0 2.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABX13211.1 - 2.1e-07 30.8 0.0 3.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABX13211.1 - 2.1e-06 27.7 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABX13211.1 - 4.4e-06 27.4 0.0 7.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ABX13211.1 - 0.0085 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 ABX13211.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MFS_1 PF07690.16 ABX13212.1 - 9.8e-48 162.9 64.0 3.1e-36 125.0 35.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABX13212.1 - 7.7e-16 58.3 16.0 1.1e-15 57.9 16.0 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 ABX13212.1 - 0.005 15.2 14.3 0.02 13.2 2.8 3.5 1 1 3 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MASE2 PF05230.11 ABX13212.1 - 0.0073 16.4 0.2 0.0073 16.4 0.2 2.9 3 0 0 3 3 3 1 MASE2 domain Phage_holin_8 PF16931.5 ABX13212.1 - 0.016 15.2 0.1 0.016 15.2 0.1 2.4 2 0 0 2 2 2 0 Putative phage holin P-II PF00543.22 ABX13213.1 - 2.4e-17 63.4 0.9 7e-17 61.9 0.9 1.6 1 1 0 1 1 1 1 Nitrogen regulatory protein P-II HisG_C PF08029.11 ABX13213.1 - 0.0039 17.3 0.5 0.045 13.9 0.4 2.1 2 0 0 2 2 2 1 HisG, C-terminal domain Nit_Regul_Hom PF10126.9 ABX13213.1 - 0.13 12.3 0.0 8.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII MttA_Hcf106 PF02416.16 ABX13214.1 - 6.4e-09 35.0 0.9 8.8e-09 34.6 0.8 1.4 1 1 0 1 1 1 1 mttA/Hcf106 family DUF4389 PF14333.6 ABX13214.1 - 0.0048 16.8 0.0 0.0064 16.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4389) Laminin_II PF06009.12 ABX13214.1 - 0.017 15.2 0.3 0.023 14.7 0.3 1.3 1 1 0 1 1 1 0 Laminin Domain II DUF948 PF06103.11 ABX13214.1 - 0.064 13.5 0.1 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) N6_N4_Mtase PF01555.18 ABX13215.1 - 8.8e-40 136.8 4.9 1e-39 136.6 4.9 1.0 1 0 0 1 1 1 1 DNA methylase N6_Mtase PF02384.16 ABX13215.1 - 0.00025 20.4 0.1 0.035 13.4 0.1 2.1 2 0 0 2 2 2 2 N-6 DNA Methylase MethyltransfD12 PF02086.15 ABX13215.1 - 0.00092 19.0 0.3 0.0048 16.6 0.0 2.1 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase UPF0020 PF01170.18 ABX13215.1 - 0.0018 18.0 0.0 0.49 10.1 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 MT-A70 PF05063.14 ABX13215.1 - 0.025 14.5 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 MT-A70 N6-adenineMlase PF10237.9 ABX13215.1 - 0.028 14.2 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase DEAD PF00270.29 ABX13216.1 - 5.7e-35 120.7 0.3 4.5e-34 117.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ABX13216.1 - 9.1e-19 67.8 2.2 1.2e-13 51.4 0.3 3.7 4 0 0 4 4 4 2 Helicase conserved C-terminal domain DUF1998 PF09369.10 ABX13216.1 - 5.6e-10 39.8 0.1 1.6e-09 38.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) adh_short PF00106.25 ABX13217.1 - 6.2e-52 175.9 0.0 8.2e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABX13217.1 - 4.2e-38 131.2 0.0 5.5e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABX13217.1 - 4.2e-09 36.6 0.0 6.4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 ABX13217.1 - 6.5e-08 32.4 0.2 3.4e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family DUF1776 PF08643.10 ABX13217.1 - 6.4e-05 22.5 0.0 9.7e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 ABX13217.1 - 0.005 16.7 0.1 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 ABX13217.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 ABX13217.1 - 0.074 12.8 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Topoisom_I_N PF02919.15 ABX13218.1 - 6.2e-71 238.3 7.6 6.2e-71 238.3 7.6 3.4 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 ABX13218.1 - 1.6e-68 230.4 16.9 1.6e-68 230.4 16.9 2.5 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 ABX13218.1 - 2.6e-20 72.1 2.7 2.6e-20 72.1 2.7 4.5 6 1 0 6 6 6 1 C-terminal topoisomerase domain BST2 PF16716.5 ABX13218.1 - 1.5 9.5 30.0 0.33 11.5 14.4 3.5 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Phage_integrase PF00589.22 ABX13220.1 - 2.8e-11 43.5 0.1 7.4e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 Phage integrase family DZR PF12773.7 ABX13220.1 - 0.0063 16.5 0.9 0.013 15.5 0.9 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf_C2H2_13 PF18508.1 ABX13220.1 - 0.034 13.7 0.2 0.097 12.3 0.2 1.7 1 0 0 1 1 1 0 Zinc finger domain zinc_ribbon_2 PF13240.6 ABX13220.1 - 0.076 12.8 3.3 0.18 11.6 3.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Phage_int_SAM_4 PF13495.6 ABX13220.1 - 0.085 13.3 1.0 0.29 11.6 1.0 1.9 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain zf-C3HC PF07967.13 ABX13220.1 - 0.12 12.4 1.5 0.31 11.1 1.5 1.7 1 0 0 1 1 1 0 C3HC zinc finger-like zf-RanBP PF00641.18 ABX13220.1 - 0.4 10.0 2.7 0.65 9.4 2.7 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others TSP_3 PF02412.18 ABX13221.1 - 4.5e-08 32.6 36.2 0.00057 19.5 1.6 3.7 3 0 0 3 3 3 3 Thrombospondin type 3 repeat HTH_24 PF13412.6 ABX13222.1 - 3.4e-14 52.1 0.1 4.2e-08 32.6 0.0 2.9 3 1 0 3 3 3 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 ABX13222.1 - 1.6e-12 47.1 0.4 1.7e-08 34.2 0.1 2.4 2 1 0 2 2 2 2 Bacterial regulatory protein, arsR family TrmB PF01978.19 ABX13222.1 - 1.2e-10 41.1 0.1 6.9e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 ABX13222.1 - 4.9e-09 36.1 0.0 2.4e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain FaeA PF04703.12 ABX13222.1 - 3.3e-07 30.6 0.2 0.00044 20.6 0.0 2.8 2 1 1 3 3 3 1 FaeA-like protein HTH_34 PF13601.6 ABX13222.1 - 3.3e-07 30.4 0.4 0.0066 16.6 0.0 2.2 2 0 0 2 2 2 2 Winged helix DNA-binding domain MarR PF01047.22 ABX13222.1 - 2.1e-06 27.5 0.2 0.0016 18.3 0.1 2.4 2 0 0 2 2 2 2 MarR family HTH_40 PF14493.6 ABX13222.1 - 8e-06 26.2 0.1 0.029 14.8 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_11 PF08279.12 ABX13222.1 - 1.8e-05 24.6 0.1 0.0053 16.7 0.0 2.4 2 0 0 2 2 2 1 HTH domain Penicillinase_R PF03965.16 ABX13222.1 - 3.4e-05 24.2 0.9 0.0007 19.9 0.1 2.2 2 0 0 2 2 2 1 Penicillinase repressor MarR_2 PF12802.7 ABX13222.1 - 0.00014 21.7 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 MarR family HTH_IclR PF09339.10 ABX13222.1 - 0.00018 21.3 0.0 0.44 10.4 0.0 2.3 2 0 0 2 2 2 2 IclR helix-turn-helix domain RepL PF05732.11 ABX13222.1 - 0.00024 20.6 0.0 0.012 15.1 0.0 2.2 2 0 0 2 2 2 1 Firmicute plasmid replication protein (RepL) LexA_DNA_bind PF01726.16 ABX13222.1 - 0.00052 19.7 0.2 0.83 9.5 0.0 2.9 2 2 1 3 3 3 2 LexA DNA binding domain HTH_Crp_2 PF13545.6 ABX13222.1 - 0.00066 19.6 0.0 0.0098 15.9 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain PadR PF03551.14 ABX13222.1 - 0.0018 18.2 2.4 0.024 14.6 0.2 2.6 2 1 0 2 2 2 1 Transcriptional regulator PadR-like family GerE PF00196.19 ABX13222.1 - 0.0018 17.8 0.1 0.038 13.5 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Rrf2 PF02082.20 ABX13222.1 - 0.002 18.4 0.2 0.098 13.0 0.1 2.2 2 0 0 2 2 2 1 Transcriptional regulator HTH_41 PF14502.6 ABX13222.1 - 0.0039 16.8 0.1 0.071 12.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain BLACT_WH PF17778.1 ABX13222.1 - 0.0063 16.5 0.0 0.3 11.1 0.0 2.5 3 0 0 3 3 2 1 Beta-lactamase associated winged helix domain HTH_9 PF08221.11 ABX13222.1 - 0.0096 16.0 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain FUR PF01475.19 ABX13222.1 - 0.011 15.9 3.7 0.098 12.8 0.5 2.5 1 1 1 2 2 2 0 Ferric uptake regulator family Sigma70_r4 PF04545.16 ABX13222.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_45 PF14947.6 ABX13222.1 - 0.017 15.1 2.3 3.8 7.6 0.4 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix HTH_27 PF13463.6 ABX13222.1 - 0.051 14.1 0.0 13 6.4 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain PaaX PF07848.12 ABX13222.1 - 0.057 13.6 0.0 16 5.8 0.0 2.4 2 0 0 2 2 2 0 PaaX-like protein Sigma70_r4_2 PF08281.12 ABX13222.1 - 0.093 12.4 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 Bac_DnaA_C PF08299.11 ABX13222.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix HRG PF16954.5 ABX13223.1 - 0.035 14.5 3.4 0.035 14.5 3.4 2.2 2 1 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF4199 PF13858.6 ABX13223.1 - 0.037 14.4 6.7 0.68 10.3 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Ndc1_Nup PF09531.10 ABX13223.1 - 0.14 10.8 1.5 0.15 10.7 1.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MG2 PF01835.19 ABX13224.1 - 4.3e-18 65.6 0.2 1.5e-05 25.3 0.0 4.3 4 0 0 4 4 4 4 MG2 domain FlgD_ig PF13860.6 ABX13224.1 - 1.3e-06 28.2 3.5 0.14 12.0 0.1 4.3 4 0 0 4 4 4 3 FlgD Ig-like domain Big_7 PF17957.1 ABX13224.1 - 1.5e-05 25.7 12.0 0.0011 19.7 0.3 5.5 2 2 2 4 4 4 1 Bacterial Ig domain DUF3244 PF11589.8 ABX13224.1 - 0.0087 16.1 0.2 0.0087 16.1 0.2 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF3244) MG4 PF17789.1 ABX13224.1 - 0.027 14.6 0.7 36 4.6 0.0 3.7 4 0 0 4 4 4 0 Macroglobulin domain MG4 CarboxypepD_reg PF13620.6 ABX13225.1 - 0.00058 20.1 0.1 0.001 19.3 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Glyco_transf_15 PF01793.16 ABX13226.1 - 0.056 12.7 1.7 0.058 12.6 1.7 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase CENP-I PF07778.11 ABX13226.1 - 1.8 7.2 9.5 2 7.0 9.5 1.0 1 0 0 1 1 1 0 Mis6 ParBc PF02195.18 ABX13227.1 - 6.8e-19 68.0 0.2 1.7e-18 66.7 0.2 1.7 1 0 0 1 1 1 1 ParB-like nuclease domain Tn7_Tnp_TnsA_C PF08721.11 ABX13227.1 - 0.079 13.6 1.6 13 6.5 0.1 3.0 3 0 0 3 3 3 0 TnsA endonuclease C terminal DUF2924 PF11149.8 ABX13227.1 - 0.36 11.2 4.0 0.18 12.2 0.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2924) Usp PF00582.26 ABX13228.1 - 7.5e-13 49.2 0.0 9.2e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF262 PF03235.14 ABX13229.1 - 0.078 13.1 6.3 0.097 12.8 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 MBR1 PF17058.5 ABX13229.1 - 0.23 11.7 6.7 0.27 11.5 6.7 1.1 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 Asp-B-Hydro_N PF05279.11 ABX13229.1 - 0.58 10.2 5.7 0.72 9.9 5.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Exonuc_VII_L PF02601.15 ABX13229.1 - 0.72 9.4 8.8 0.87 9.1 8.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CCDC-167 PF15188.6 ABX13229.1 - 1.3 9.4 11.5 4.1 7.8 3.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 YojJ PF10372.9 ABX13229.1 - 1.7 8.8 6.4 1.6 8.8 1.4 2.2 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus YlqD PF11068.8 ABX13229.1 - 2.3 8.6 18.7 0.69 10.3 9.5 2.1 1 1 1 2 2 2 0 YlqD protein Atg14 PF10186.9 ABX13229.1 - 2.6 7.1 17.4 3.1 6.8 17.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DNA_topoisoIV PF00521.20 ABX13229.1 - 3 6.6 12.6 3.4 6.4 12.6 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF1664 PF07889.12 ABX13229.1 - 4.8 7.3 10.4 6.5 6.8 10.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 ABX13229.1 - 8.7 6.5 16.9 22 5.2 16.8 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 ABX13229.1 - 9.7 5.4 12.2 19 4.4 12.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Usp PF00582.26 ABX13230.1 - 7.1e-21 75.2 0.0 7.9e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Dishevelled PF02377.15 ABX13230.1 - 0.018 15.5 0.1 0.02 15.4 0.1 1.2 1 0 0 1 1 1 0 Dishevelled specific domain XOO_2897-deam PF14440.6 ABX13230.1 - 0.068 13.3 0.2 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase G-gamma PF00631.22 ABX13230.1 - 0.12 12.4 0.5 0.28 11.2 0.5 1.7 1 1 0 1 1 1 0 GGL domain MS_channel PF00924.18 ABX13231.1 - 2.1e-48 164.6 0.3 2.1e-48 164.6 0.3 1.4 2 0 0 2 2 2 1 Mechanosensitive ion channel Ni_hydr_CYTB PF01292.20 ABX13231.1 - 0.012 15.2 0.6 0.022 14.4 0.6 1.5 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF432 PF04254.13 ABX13232.1 - 5.1e-33 113.9 0.0 8.4e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF432) MS_channel PF00924.18 ABX13233.1 - 2.8e-16 59.7 2.6 3.1e-16 59.5 2.6 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel ParcG PF10274.9 ABX13233.1 - 0.0036 17.4 0.0 0.0042 17.2 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein HTH_45 PF14947.6 ABX13234.1 - 5.4e-05 23.1 0.1 0.00019 21.3 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DUF1724 PF08350.10 ABX13234.1 - 0.0019 18.3 0.1 0.0038 17.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1724) MarR_2 PF12802.7 ABX13234.1 - 0.0028 17.5 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 MarR family DUF4423 PF14394.6 ABX13234.1 - 0.0029 17.3 0.1 0.0053 16.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_24 PF13412.6 ABX13234.1 - 0.0044 16.5 0.1 0.025 14.1 0.1 2.4 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABX13234.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 ABX13234.1 - 0.042 14.2 0.0 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator HxlR PF01638.17 ABX13234.1 - 0.052 13.4 0.1 0.16 11.8 0.1 1.8 1 0 0 1 1 1 0 HxlR-like helix-turn-helix RuvB_C PF05491.13 ABX13234.1 - 0.054 13.4 0.1 0.16 11.8 0.1 1.8 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain Dimerisation2 PF16864.5 ABX13234.1 - 0.072 13.1 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Dimerisation domain HTH_5 PF01022.20 ABX13234.1 - 0.078 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABX13234.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.6 ABX13234.1 - 0.17 12.4 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain AsnC_trans_reg PF01037.21 ABX13235.1 - 0.0013 18.6 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HisG PF01634.18 ABX13235.1 - 0.052 13.5 0.0 0.055 13.4 0.0 1.0 1 0 0 1 1 1 0 ATP phosphoribosyltransferase DUF4932 PF16286.5 ABX13235.1 - 0.21 10.8 0.0 0.21 10.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) TFIIB PF00382.19 ABX13236.1 - 6.3e-36 122.3 9.6 2.6e-19 69.0 2.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ABX13236.1 - 2.2e-09 36.7 1.9 3.7e-09 36.0 1.9 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 ABX13236.1 - 2.9e-06 27.1 0.9 0.00018 21.3 0.3 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sigma70_r4 PF04545.16 ABX13236.1 - 1.1e-05 24.9 0.4 0.028 14.0 0.0 2.9 3 0 0 3 3 3 2 Sigma-70, region 4 zf-ribbon_3 PF13248.6 ABX13236.1 - 0.00065 19.0 3.6 0.01 15.2 3.6 2.3 1 1 0 1 1 1 1 zinc-ribbon domain Ribosomal_S27e PF01667.17 ABX13236.1 - 0.00096 18.8 1.2 0.0019 17.8 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 HTH_3 PF01381.22 ABX13236.1 - 0.0031 17.5 0.1 0.56 10.3 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix RB_B PF01857.20 ABX13236.1 - 0.0054 16.8 0.3 0.0092 16.0 0.3 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DZR PF12773.7 ABX13236.1 - 0.0066 16.5 0.4 0.015 15.3 0.4 1.6 1 0 0 1 1 1 1 Double zinc ribbon HTH_11 PF08279.12 ABX13236.1 - 0.012 15.6 2.2 0.038 13.9 0.0 2.6 3 0 0 3 3 3 0 HTH domain HTH_AsnC-type PF13404.6 ABX13236.1 - 0.015 15.1 1.8 0.3 10.9 0.0 3.0 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Lar_restr_allev PF14354.6 ABX13236.1 - 0.016 15.6 0.5 0.05 14.0 0.5 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.10 ABX13236.1 - 0.024 14.3 1.2 0.042 13.6 1.2 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.6 ABX13236.1 - 0.024 14.3 3.7 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 ABX13236.1 - 0.028 14.5 0.6 0.43 10.7 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 ABX13236.1 - 0.036 13.6 1.4 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HTH_Crp_2 PF13545.6 ABX13236.1 - 0.055 13.5 0.2 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain YacG PF03884.14 ABX13236.1 - 0.11 12.3 0.5 0.24 11.2 0.5 1.6 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG HTH_24 PF13412.6 ABX13236.1 - 0.13 11.9 0.4 2.2 7.9 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding GerE PF00196.19 ABX13236.1 - 0.14 11.7 2.4 2 8.0 0.0 3.2 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family HrcA_DNA-bdg PF03444.15 ABX13236.1 - 0.15 11.8 1.2 7.2 6.3 0.0 3.0 2 1 1 3 3 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Sigma70_r4_2 PF08281.12 ABX13236.1 - 0.16 11.6 4.3 0.19 11.4 0.0 3.1 4 0 0 4 4 4 0 Sigma-70, region 4 OrfB_Zn_ribbon PF07282.11 ABX13236.1 - 0.19 11.7 3.0 0.15 12.0 0.4 2.2 2 0 0 2 2 1 0 Putative transposase DNA-binding domain Mu-like_Com PF10122.9 ABX13236.1 - 0.32 10.5 2.2 0.33 10.4 0.7 1.9 1 1 0 1 1 1 0 Mu-like prophage protein Com Rrf2 PF02082.20 ABX13236.1 - 0.38 11.1 1.9 62 4.0 0.0 3.6 2 2 2 4 4 4 0 Transcriptional regulator TFIIB PF00382.19 ABX13237.1 - 3.3e-23 81.5 1.6 3.6e-11 43.0 0.4 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ABX13237.1 - 0.0035 16.8 2.0 0.0068 15.9 2.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 ABX13237.1 - 0.006 16.3 0.1 3.5 7.4 0.0 2.3 1 1 1 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 ABX13237.1 - 0.0074 16.4 0.0 2.7 8.1 0.0 2.4 1 1 1 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 ABX13237.1 - 0.029 13.9 0.4 0.55 9.8 0.0 3.1 4 1 0 4 4 4 0 Sigma-70, region 4 HTH_36 PF13730.6 ABX13237.1 - 0.14 12.1 1.2 3.1 7.8 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain zf-ACC PF17848.1 ABX13237.1 - 0.19 11.8 1.4 22 5.2 0.1 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain MS_channel PF00924.18 ABX13238.1 - 6.4e-08 32.4 2.1 6.4e-08 32.4 2.1 1.5 2 0 0 2 2 2 1 Mechanosensitive ion channel MASE5 PF17178.4 ABX13238.1 - 0.46 10.3 5.8 0.59 9.9 5.8 1.1 1 0 0 1 1 1 0 Membrane-associated sensor PhyH PF05721.13 ABX13239.1 - 1.1e-33 117.2 0.0 1.4e-33 117.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF5070 PF16802.5 ABX13239.1 - 0.067 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5070) Ectoine_synth PF06339.12 ABX13240.1 - 3.9e-59 198.4 0.1 4.4e-59 198.2 0.1 1.0 1 0 0 1 1 1 1 Ectoine synthase Cupin_2 PF07883.11 ABX13240.1 - 2.3e-06 27.2 0.3 3.1e-06 26.8 0.3 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 ABX13240.1 - 0.025 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.19 ABX13240.1 - 0.026 14.4 0.1 0.034 14.1 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Pirin_C PF05726.13 ABX13240.1 - 0.074 13.4 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Pirin C-terminal cupin domain Aminotran_3 PF00202.21 ABX13241.1 - 3.6e-78 263.0 0.0 4.4e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Acetyltransf_1 PF00583.25 ABX13242.1 - 1.6e-11 44.4 0.0 2.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ABX13242.1 - 2.5e-06 27.8 0.0 3.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABX13242.1 - 3.2e-05 23.9 0.0 4.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ABX13242.1 - 0.00082 20.1 0.0 0.0015 19.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ABX13242.1 - 0.0066 16.5 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 ABX13242.1 - 0.012 15.1 0.0 0.029 13.8 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase DUF4821 PF16092.5 ABX13242.1 - 0.013 15.1 0.0 0.049 13.3 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4821) Acetyltransf_9 PF13527.7 ABX13242.1 - 0.063 13.4 0.0 0.27 11.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1287 PF06940.11 ABX13243.1 - 0.092 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) eIF-1a PF01176.19 ABX13244.1 - 3e-16 59.0 2.0 4.2e-16 58.5 2.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 NPFF PF15085.6 ABX13244.1 - 0.04 14.3 0.0 0.047 14.0 0.0 1.1 1 0 0 1 1 1 0 Neuropeptide FF dCache_1 PF02743.18 ABX13245.1 - 1.4e-13 51.3 1.3 1.4e-13 51.3 1.3 1.8 2 0 0 2 2 2 1 Cache domain HAMP PF00672.25 ABX13245.1 - 1.4e-11 44.5 0.0 3.8e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 HAMP domain Guanylate_cyc PF00211.20 ABX13245.1 - 1.2e-06 28.3 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain IFT57 PF10498.9 ABX13245.1 - 0.06 12.3 1.2 0.11 11.4 1.2 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BORCS8 PF10167.9 ABX13245.1 - 0.11 12.5 0.7 1.8 8.5 0.4 2.5 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 SEA PF01390.20 ABX13245.1 - 1 9.5 5.0 1.7 8.8 0.9 2.6 2 0 0 2 2 2 0 SEA domain 7TM_GPCR_Srj PF10319.9 ABX13247.1 - 0.00027 20.4 1.1 0.00034 20.1 0.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srj HTH_5 PF01022.20 ABX13248.1 - 6e-07 29.2 0.2 1.4e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABX13248.1 - 9.8e-07 28.7 0.4 4.4e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 ABX13248.1 - 5.1e-05 23.1 0.0 0.0027 17.6 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 ABX13248.1 - 0.0024 17.8 0.0 0.0057 16.6 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 ABX13248.1 - 0.003 17.4 0.1 0.054 13.4 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 ABX13248.1 - 0.0099 15.6 0.0 0.033 13.9 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4423) DUF1724 PF08350.10 ABX13248.1 - 0.015 15.4 0.3 0.028 14.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) DUF505 PF04458.12 ABX13248.1 - 0.028 12.8 0.0 0.035 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF505) MarR PF01047.22 ABX13248.1 - 0.061 13.3 0.1 4 7.4 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 ABX13248.1 - 0.064 12.8 0.1 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Hemerythrin PF01814.23 ABX13249.1 - 6.2e-12 46.3 2.0 9.8e-12 45.6 2.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain tRNA_NucTran2_2 PF13735.6 ABX13249.1 - 0.053 13.5 0.1 0.094 12.7 0.1 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Cu-oxidase_3 PF07732.15 ABX13250.1 - 3.2e-26 91.7 4.6 5.3e-24 84.5 0.1 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ABX13250.1 - 1.6e-14 53.8 12.2 6.9e-05 22.6 0.1 4.1 5 0 0 5 5 5 3 Multicopper oxidase Copper-bind PF00127.20 ABX13250.1 - 1.4e-10 41.5 2.5 1.6e-05 25.2 0.1 3.9 3 1 0 3 3 3 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX13250.1 - 9.6e-10 38.5 0.0 2.6e-05 24.2 0.0 3.4 3 0 0 3 3 3 2 Cupredoxin-like domain Flavodoxin_1 PF00258.25 ABX13252.1 - 2.8e-21 76.2 0.1 3.2e-21 76.0 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 ABX13252.1 - 0.046 13.4 0.0 0.067 12.9 0.0 1.5 1 1 0 1 1 1 0 Flavodoxin domain Flavodoxin_5 PF12724.7 ABX13252.1 - 0.11 12.8 0.0 0.45 10.7 0.0 2.0 2 1 0 2 2 2 0 Flavodoxin domain Jun PF03957.13 ABX13252.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Jun-like transcription factor AhpC-TSA PF00578.21 ABX13252.1 - 0.17 11.8 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Nitroreductase PF00881.24 ABX13253.1 - 1.4e-23 83.8 0.7 7.7e-13 48.8 0.2 2.2 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 ABX13253.1 - 5.4e-09 35.9 0.6 0.0015 18.2 0.0 2.7 2 1 0 2 2 2 2 Putative TM nitroreductase PK PF00224.21 ABX13253.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Kazal_1 PF00050.21 ABX13254.1 - 5.6e-09 35.9 0.3 1.9e-08 34.2 0.3 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 ABX13254.1 - 3.1e-05 24.0 4.0 0.00015 21.8 1.5 2.7 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Lactamase_B PF00753.27 ABX13254.1 - 0.00041 20.4 5.1 0.00094 19.2 3.1 2.2 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily HTH_5 PF01022.20 ABX13255.1 - 9.1e-08 31.8 0.2 1.8e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABX13255.1 - 5.2e-06 26.4 0.0 8.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 ABX13255.1 - 0.00036 20.0 0.0 0.0009 18.8 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 ABX13255.1 - 0.00065 19.6 0.1 0.0013 18.6 0.1 1.5 1 0 0 1 1 1 1 HTH domain TFIIE_alpha PF02002.17 ABX13255.1 - 0.0097 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 TFIIE alpha subunit Uroplakin_II PF07353.12 ABX13255.1 - 0.019 14.5 0.5 0.034 13.7 0.5 1.4 1 0 0 1 1 1 0 Uroplakin II SPOC PF07744.13 ABX13255.1 - 0.045 13.7 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 SPOC domain PI31_Prot_N PF11566.8 ABX13255.1 - 0.061 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal HTH_41 PF14502.6 ABX13255.1 - 0.064 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Mga PF05043.13 ABX13255.1 - 0.067 13.8 0.4 0.14 12.8 0.4 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain SIMPL PF04402.14 ABX13256.1 - 1.8e-42 146.1 3.6 2.3e-42 145.7 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DeoC PF01791.9 ABX13256.1 - 0.025 14.2 0.6 0.038 13.6 0.6 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase TrmB PF01978.19 ABX13258.1 - 0.00013 21.8 0.1 0.00033 20.5 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 ABX13258.1 - 0.017 15.0 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 ABX13258.1 - 0.032 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.7 ABX13258.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 ABX13258.1 - 0.12 12.0 0.4 0.59 9.7 0.1 2.3 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding zf-ribbon_3 PF13248.6 ABX13260.1 - 0.0046 16.3 0.9 0.016 14.6 0.1 2.1 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 ABX13260.1 - 0.013 15.2 0.3 0.031 14.0 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Cys_rich_CPXG PF14255.6 ABX13260.1 - 2.9 7.9 6.8 0.29 11.0 1.2 2.1 3 0 0 3 3 3 0 Cysteine-rich CPXCG Cupredoxin_1 PF13473.6 ABX13261.1 - 2.7e-05 24.2 0.1 3.4e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Methyltransf_11 PF08241.12 ABX13262.1 - 1.6e-08 35.0 0.0 3.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX13262.1 - 1.9e-08 34.9 0.0 3.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABX13262.1 - 2.6e-08 33.9 0.0 5.6e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABX13262.1 - 4e-06 27.5 0.0 9.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABX13262.1 - 4.5e-06 26.5 0.0 7.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Trm112p PF03966.16 ABX13262.1 - 7.7e-05 23.2 0.3 0.00081 19.9 0.2 2.3 2 0 0 2 2 2 1 Trm112p-like protein NodS PF05401.11 ABX13262.1 - 0.0019 17.9 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 ABX13262.1 - 0.0039 16.3 0.1 0.0065 15.6 0.1 1.4 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 ABX13262.1 - 0.0041 16.7 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF4125 PF13526.6 ABX13262.1 - 0.014 15.0 0.4 0.025 14.2 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4125) Elf1 PF05129.13 ABX13262.1 - 0.053 13.6 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like A2L_zn_ribbon PF08792.10 ABX13262.1 - 0.056 13.2 1.1 0.17 11.6 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.12 ABX13262.1 - 0.45 10.1 1.8 0.75 9.4 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding NADPH_Ox PF08414.10 ABX13263.1 - 0.0098 16.2 1.0 0.31 11.4 0.1 3.0 2 1 0 2 2 2 1 Respiratory burst NADPH oxidase Acetyltransf_6 PF13480.7 ABX13263.1 - 0.2 11.8 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Transglut_core2 PF13369.6 ABX13264.1 - 2.6e-41 140.8 0.0 3.5e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 ABX13264.1 - 2.7e-17 62.7 0.0 4e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ABX13264.1 - 3e-06 27.2 0.3 0.1 12.7 0.1 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 ABX13264.1 - 2.4e-05 24.0 1.1 0.0057 16.4 0.6 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ABX13264.1 - 0.00012 21.9 0.1 0.011 15.8 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ABX13264.1 - 0.014 16.1 0.0 0.48 11.4 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ABX13264.1 - 0.029 14.6 0.1 0.098 12.9 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat CRF-BP PF05428.11 ABX13264.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) DUF5452 PF17533.2 ABX13264.1 - 0.25 11.4 4.2 0.68 10.0 0.7 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5452) DivIC PF04977.15 ABX13265.1 - 0.0021 17.8 1.5 0.0033 17.2 1.5 1.4 1 1 0 1 1 1 1 Septum formation initiator CCD48 PF15799.5 ABX13265.1 - 0.037 12.4 0.1 0.037 12.4 0.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 NUDE_C PF04880.13 ABX13265.1 - 0.055 14.0 0.5 0.059 13.8 0.5 1.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF1192 PF06698.11 ABX13265.1 - 0.088 12.9 2.8 0.13 12.3 2.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) TetR_C_11 PF16859.5 ABX13266.1 - 0.00022 21.5 1.3 10 6.4 0.1 4.7 3 2 2 5 5 5 1 Tetracyclin repressor-like, C-terminal domain Bep_C_terminal PF17841.1 ABX13266.1 - 0.0019 18.4 23.8 0.54 10.5 0.4 6.2 4 2 2 6 6 6 3 BID domain of Bartonella effector protein (Bep) MethyTransf_Reg PF10119.9 ABX13266.1 - 0.019 15.7 14.0 1.2 9.9 0.1 5.3 4 2 1 5 5 5 0 Predicted methyltransferase regulatory domain TetR_C_28 PF17937.1 ABX13266.1 - 0.023 15.1 17.4 0.027 14.9 3.0 5.4 3 2 2 5 5 5 0 Tetracyclin repressor-like, C-terminal domain DUF5408 PF17402.2 ABX13266.1 - 0.062 13.2 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5408) SATase_N PF06426.14 ABX13266.1 - 0.21 11.9 7.9 8.1 6.9 0.1 4.4 2 2 2 4 4 4 0 Serine acetyltransferase, N-terminal Cation_efflux PF01545.21 ABX13267.1 - 2e-17 63.6 13.5 1.1e-15 58.0 13.5 2.0 1 1 0 1 1 1 1 Cation efflux family HTH_5 PF01022.20 ABX13268.1 - 9.3e-16 57.4 0.9 4.1e-15 55.4 0.7 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABX13268.1 - 4e-07 30.0 0.0 5.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 ABX13268.1 - 4.1e-06 26.6 0.0 7.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 ABX13268.1 - 3.8e-05 23.5 0.0 5.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABX13268.1 - 4.1e-05 24.0 0.0 6.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_34 PF13601.6 ABX13268.1 - 0.00013 22.0 0.1 0.00019 21.6 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 ABX13268.1 - 0.00036 20.3 0.0 0.00073 19.3 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 ABX13268.1 - 0.001 18.6 0.1 0.002 17.7 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF1495 PF07381.11 ABX13268.1 - 0.0016 18.3 0.1 0.049 13.5 0.1 2.1 1 1 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) HTH_45 PF14947.6 ABX13268.1 - 0.0021 18.0 0.1 0.0032 17.4 0.1 1.4 1 1 0 1 1 1 1 Winged helix-turn-helix DUF4423 PF14394.6 ABX13268.1 - 0.014 15.1 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Cdc6_C PF09079.11 ABX13268.1 - 0.02 14.9 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain RP-C PF03428.13 ABX13268.1 - 0.035 13.8 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Fe_dep_repress PF01325.19 ABX13268.1 - 0.045 14.0 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_40 PF14493.6 ABX13268.1 - 0.068 13.6 0.0 0.1 13.1 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 ABX13268.1 - 0.077 12.9 0.2 0.12 12.2 0.2 1.4 1 1 0 1 1 1 0 TFIIE alpha subunit MarR PF01047.22 ABX13268.1 - 0.094 12.7 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 MarR family DUF3377 PF11857.8 ABX13269.1 - 0.81 9.7 5.2 1.2 9.1 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) zf-NPL4 PF05020.15 ABX13270.1 - 0.0093 16.1 0.9 0.01 16.0 0.9 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region RepA_C PF04796.12 ABX13270.1 - 0.054 13.5 0.7 0.073 13.1 0.7 1.1 1 0 0 1 1 1 0 Plasmid encoded RepA protein Phage_integrase PF00589.22 ABX13273.1 - 6e-08 32.7 0.0 1.6e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Phage integrase family SRP54_N PF02881.19 ABX13273.1 - 0.018 15.3 0.2 0.98 9.7 0.0 3.6 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain Metallophos PF00149.28 ABX13274.1 - 1.5e-18 68.0 0.3 2.4e-18 67.4 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ABX13274.1 - 9.4e-16 58.4 0.1 1.4e-15 57.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 ABX13274.1 - 8.9e-06 25.2 0.4 0.00022 20.6 0.1 2.3 1 1 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily DUF2124 PF09897.9 ABX13274.1 - 0.0032 17.4 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2124) Iso_dh PF00180.20 ABX13275.1 - 6e-80 269.0 0.3 7e-80 268.8 0.3 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MTS PF05175.14 ABX13276.1 - 3.5e-10 39.7 0.0 1e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 ABX13276.1 - 9.6e-09 35.2 0.7 2.1e-08 34.1 0.7 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABX13276.1 - 4.6e-08 33.1 0.0 3.1e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABX13276.1 - 1.3e-06 29.0 0.0 3.2e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX13276.1 - 2.9e-05 24.7 0.0 0.00015 22.4 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABX13276.1 - 0.00027 21.6 0.2 0.00078 20.1 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 ABX13276.1 - 0.00074 18.7 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.19 ABX13276.1 - 0.0014 18.4 0.0 0.0062 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 ABX13276.1 - 0.0016 18.5 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 ABX13276.1 - 0.002 17.8 0.0 0.0035 17.0 0.0 1.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 ABX13276.1 - 0.026 14.4 0.3 0.16 11.9 0.3 2.2 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 ABX13276.1 - 0.046 12.8 0.1 0.45 9.5 0.0 2.0 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase RrnaAD PF00398.20 ABX13277.1 - 5e-39 134.0 4.9 6.9e-39 133.5 4.9 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 ABX13277.1 - 2.6e-06 27.3 1.1 9.3e-06 25.5 1.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ABX13277.1 - 9.6e-05 22.2 0.0 0.00016 21.5 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ABX13277.1 - 0.0002 20.9 0.1 0.00038 20.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ABX13277.1 - 0.00053 20.6 0.0 0.0016 19.1 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABX13277.1 - 0.0013 19.4 0.1 0.0064 17.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 ABX13277.1 - 0.0034 17.3 0.3 0.0092 15.9 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABX13277.1 - 0.012 16.3 0.0 0.04 14.6 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 ABX13277.1 - 0.018 14.9 0.0 0.024 14.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 ABX13277.1 - 0.046 13.7 0.3 0.085 12.8 0.3 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF655 PF04919.12 ABX13278.1 - 3e-50 170.7 0.8 3.3e-50 170.5 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.6 ABX13278.1 - 0.00023 21.4 0.0 0.00071 19.8 0.0 1.9 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.7 ABX13278.1 - 0.0062 16.8 0.0 0.045 14.0 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif Dynamitin PF04912.14 ABX13278.1 - 0.029 13.7 0.2 0.035 13.5 0.2 1.1 1 0 0 1 1 1 0 Dynamitin 4HB_MCP_1 PF12729.7 ABX13278.1 - 0.12 12.0 2.9 1.5 8.3 0.2 2.2 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction RNA_pol_Rpb4 PF03874.16 ABX13279.1 - 1.2e-08 35.3 1.5 2.4e-08 34.4 1.5 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF4844 PF16133.5 ABX13279.1 - 0.021 15.4 0.1 0.039 14.5 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4844) Integrase_Zn PF02022.19 ABX13279.1 - 0.17 11.9 0.0 19 5.3 0.0 2.4 2 0 0 2 2 2 0 Integrase Zinc binding domain Ribosomal_L21e PF01157.18 ABX13280.1 - 1.3e-20 73.2 0.9 1.8e-20 72.7 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L21e Radical_SAM PF04055.21 ABX13281.1 - 4.9e-18 66.1 0.1 1e-17 65.0 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 ABX13281.1 - 0.0001 22.4 0.0 0.00039 20.5 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Rad51 PF08423.11 ABX13282.1 - 4.2e-88 294.9 0.0 5.6e-88 294.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 ABX13282.1 - 6.5e-10 38.9 0.1 1e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 ABX13282.1 - 1.1e-09 38.8 0.1 3.3e-09 37.2 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 ABX13282.1 - 2.2e-08 33.8 0.1 4.7e-08 32.7 0.1 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 ABX13282.1 - 2.9e-07 30.3 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ABX13282.1 - 0.00072 19.3 0.1 0.0024 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ABX13282.1 - 0.0032 18.0 0.2 0.0086 16.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter DnaB_C PF03796.15 ABX13282.1 - 0.077 12.3 0.1 3.4 6.9 0.0 2.4 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain ATPase_2 PF01637.18 ABX13282.1 - 0.12 12.3 1.0 0.83 9.5 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Ribosomal_S30 PF04758.14 ABX13283.1 - 6.6e-11 42.2 3.7 1e-10 41.6 3.7 1.4 1 1 0 1 1 1 1 Ribosomal protein S30 Radical_SAM PF04055.21 ABX13284.1 - 1.1e-09 38.8 0.0 2.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily NAD_binding_1 PF00175.21 ABX13285.1 - 3.9e-12 46.8 0.0 5.9e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.9 ABX13285.1 - 1.4e-08 34.4 8.0 2.9e-08 33.4 8.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.24 ABX13285.1 - 0.0012 19.1 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ABX13285.1 - 0.0092 16.1 0.1 1.7 8.8 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain SH3_17 PF18350.1 ABX13285.1 - 0.085 12.8 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Restriction endonuclease SH3 domain DHO_dh PF01180.21 ABX13286.1 - 1.3e-56 192.0 0.5 1.5e-56 191.8 0.5 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.17 ABX13286.1 - 1.1e-08 34.5 0.5 8.3e-06 25.1 0.1 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 ABX13286.1 - 9.3e-07 28.5 0.1 0.001 18.6 0.0 2.5 2 0 0 2 2 2 2 Histidine biosynthesis protein NMO PF03060.15 ABX13286.1 - 1.1e-05 25.0 0.2 0.00061 19.3 0.0 2.0 1 1 1 2 2 2 1 Nitronate monooxygenase DUF561 PF04481.12 ABX13286.1 - 0.00036 19.8 7.7 0.00051 19.3 0.0 3.4 3 1 0 4 4 4 1 Protein of unknown function (DUF561) IMPDH PF00478.25 ABX13286.1 - 0.00055 19.0 0.2 0.002 17.2 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain G3P_antiterm PF04309.12 ABX13286.1 - 0.00064 19.2 0.3 0.83 9.0 0.0 2.4 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 ABX13286.1 - 0.00082 18.8 2.2 0.16 11.2 0.5 2.7 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG Trp_syntA PF00290.20 ABX13286.1 - 0.062 12.1 0.1 5.6 5.7 0.0 2.4 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Nop PF01798.18 ABX13287.1 - 8.5e-66 221.7 0.0 1.6e-65 220.8 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Recep_L_domain PF01030.24 ABX13287.1 - 0.2 11.8 0.7 0.54 10.4 0.7 1.7 1 0 0 1 1 1 0 Receptor L domain Fibrillarin PF01269.17 ABX13288.1 - 6e-90 300.3 0.1 6.5e-90 300.2 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 ABX13288.1 - 0.00036 20.3 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 ABX13288.1 - 0.0027 17.5 0.0 0.0044 16.8 0.0 1.3 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4651 PF15513.6 ABX13288.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) Methyltr_RsmB-F PF01189.17 ABX13288.1 - 0.012 15.3 0.0 0.046 13.3 0.0 1.8 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ABX13288.1 - 0.098 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase RNase_HII PF01351.18 ABX13289.1 - 4.6e-44 150.6 0.2 5.2e-44 150.5 0.2 1.0 1 0 0 1 1 1 1 Ribonuclease HII TRM PF02005.16 ABX13290.1 - 1.7e-81 274.3 0.0 2e-81 274.1 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Rrf2 PF02082.20 ABX13290.1 - 0.0092 16.3 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator Met_10 PF02475.16 ABX13290.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein zf-C3HC4_3 PF13920.6 ABX13290.1 - 0.12 12.3 2.3 0.28 11.1 2.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LRV_FeS PF05484.11 ABX13290.1 - 0.29 11.2 1.5 0.73 9.9 1.5 1.6 1 0 0 1 1 1 0 LRV protein FeS4 cluster FtsJ PF01728.19 ABX13291.1 - 5.4e-50 170.0 0.0 6.1e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 ABX13291.1 - 5.7e-05 22.9 0.6 0.00036 20.3 0.6 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX13291.1 - 0.00016 22.3 0.1 0.00062 20.4 0.1 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABX13291.1 - 0.0058 16.5 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 ABX13291.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 ABX13291.1 - 0.046 13.0 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase RNA_pol_Rpc34 PF05158.12 ABX13292.1 - 1.4e-05 24.7 3.5 1.4e-05 24.7 3.5 2.4 1 1 1 2 2 2 1 RNA polymerase Rpc34 subunit MarR PF01047.22 ABX13292.1 - 0.004 17.1 0.2 0.0077 16.1 0.2 1.4 1 0 0 1 1 1 1 MarR family B-block_TFIIIC PF04182.12 ABX13292.1 - 0.092 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC PI3_PI4_kinase PF00454.27 ABX13292.1 - 0.77 9.5 0.0 0.77 9.5 0.0 2.6 1 1 1 2 2 2 0 Phosphatidylinositol 3- and 4-kinase Ndc1_Nup PF09531.10 ABX13292.1 - 1.4 7.5 18.9 1.4 7.5 18.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AAA_15 PF13175.6 ABX13294.1 - 2.1e-25 90.3 6.1 2.1e-25 90.3 6.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 ABX13294.1 - 3.2e-13 50.2 9.6 3.2e-13 50.2 2.8 3.3 2 2 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF2813 PF11398.8 ABX13294.1 - 0.001 18.4 0.6 0.62 9.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2813) ABC_tran PF00005.27 ABX13294.1 - 0.0047 17.4 2.4 0.0082 16.7 0.4 2.5 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 ABX13294.1 - 0.0051 16.5 0.3 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_27 PF13514.6 ABX13294.1 - 0.0093 15.6 0.1 0.044 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Glyco_hydro_42C PF08533.10 ABX13294.1 - 0.048 13.4 0.1 0.82 9.4 0.0 2.4 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain SMC_N PF02463.19 ABX13294.1 - 0.12 11.8 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABX13294.1 - 2.4 8.6 25.1 0.011 16.3 11.3 2.9 2 1 0 2 2 2 0 AAA domain MG2 PF01835.19 ABX13295.1 - 5.8e-23 81.2 0.1 5.3e-05 23.6 0.0 5.9 6 0 0 6 6 6 4 MG2 domain FlgD_ig PF13860.6 ABX13295.1 - 0.00031 20.5 4.1 0.96 9.4 0.1 6.0 6 1 1 7 7 7 1 FlgD Ig-like domain Big_6 PF17936.1 ABX13295.1 - 0.0059 16.9 7.5 0.073 13.4 0.0 4.7 7 0 0 7 7 7 1 Bacterial Ig domain DUF4397 PF14344.6 ABX13295.1 - 0.07 13.9 0.7 2.2 9.1 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4397) ChiW_Ig_like PF18683.1 ABX13295.1 - 0.34 11.2 4.8 13 6.1 0.3 2.7 2 0 0 2 2 2 0 Chitinase W immunoglobulin-like domain Pribosyltran PF00156.27 ABX13296.1 - 1.3e-18 67.0 0.0 1.6e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ABX13296.1 - 0.0021 17.6 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PNP_UDP_1 PF01048.20 ABX13297.1 - 2.2e-45 154.8 0.0 2.4e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily HlyD_2 PF12700.7 ABX13298.1 - 0.051 12.3 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein MRF_C2 PF13888.6 ABX13299.1 - 0.00058 19.8 0.1 0.00079 19.3 0.1 1.3 1 0 0 1 1 1 1 Myelin gene regulatory factor C-terminal domain 2 TrmB PF01978.19 ABX13300.1 - 0.00024 20.9 0.0 0.00043 20.1 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Ribosomal_S25 PF03297.15 ABX13300.1 - 0.086 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 S25 ribosomal protein RseC_MucC PF04246.12 ABX13302.1 - 0.041 13.8 0.3 0.062 13.2 0.3 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF2207 PF09972.9 ABX13302.1 - 0.1 11.4 0.6 0.13 11.0 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TP6A_N PF04406.14 ABX13303.1 - 1.2e-14 54.0 0.1 2.2e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Toprim PF01751.22 ABX13303.1 - 0.014 15.6 0.7 0.034 14.4 0.0 2.0 2 0 0 2 2 2 0 Toprim domain SIMPL PF04402.14 ABX13303.1 - 0.13 12.7 0.9 0.26 11.7 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Topo-VIb_trans PF09239.11 ABX13304.1 - 2.2e-55 186.9 0.0 4.2e-55 185.9 0.0 1.5 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c PF02518.26 ABX13304.1 - 9.1e-07 29.4 0.0 1.9e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ABX13304.1 - 0.00019 21.3 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase KH_1 PF00013.29 ABX13305.1 - 6.3e-10 38.7 5.2 0.00019 21.2 0.3 2.5 2 0 0 2 2 2 2 KH domain RIO1 PF01163.22 ABX13306.1 - 6.2e-54 182.5 0.0 8.2e-54 182.1 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ABX13306.1 - 0.0055 16.7 0.0 1.1 9.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ABX13306.1 - 0.0097 15.3 0.0 3 7.1 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Trigger_N PF05697.13 ABX13306.1 - 0.039 14.3 0.1 0.098 13.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) DUF424 PF04242.13 ABX13307.1 - 7e-24 83.9 0.1 8.1e-24 83.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF424) eIF-5_eIF-2B PF01873.17 ABX13308.1 - 2e-29 101.8 0.0 2.5e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.6 ABX13308.1 - 0.0016 18.7 0.3 0.0023 18.3 0.3 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 ABX13308.1 - 0.0028 17.1 0.6 0.005 16.3 0.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Elf1 PF05129.13 ABX13308.1 - 0.013 15.5 0.2 0.023 14.7 0.2 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PDCD2_C PF04194.13 ABX13308.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.3 1 1 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain zf-TFIIB PF13453.6 ABX13308.1 - 0.12 11.7 1.6 0.24 10.8 1.6 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger zinc_ribbon_2 PF13240.6 ABX13309.1 - 0.016 14.9 1.5 0.47 10.2 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 ABX13309.1 - 0.016 15.9 0.4 0.019 15.7 0.4 1.1 1 0 0 1 1 1 0 zinc-ribbon family DZR PF12773.7 ABX13309.1 - 0.027 14.5 1.9 0.05 13.6 1.9 1.4 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 ABX13309.1 - 0.034 14.1 0.4 0.038 14.0 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 ABX13309.1 - 0.052 13.1 2.1 1.1 8.9 0.2 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding DNA_ligase_ZBD PF03119.16 ABX13309.1 - 0.054 13.5 0.1 0.054 13.5 0.1 1.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn_ribbon_SprT PF17283.2 ABX13309.1 - 0.066 13.1 1.8 7.5 6.6 0.2 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain GFA PF04828.14 ABX13309.1 - 0.078 13.3 2.1 0.21 12.0 2.1 1.7 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.6 ABX13309.1 - 0.079 12.4 2.1 0.52 9.8 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 ABX13309.1 - 0.2 11.8 3.6 0.58 10.3 3.6 1.8 1 1 0 1 1 1 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 ABX13309.1 - 0.44 10.7 4.6 2 8.6 0.1 2.2 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Strumpellin PF10266.9 ABX13310.1 - 0.0035 15.2 0.9 0.0041 14.9 0.9 1.2 1 1 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin Styelin PF17562.2 ABX13310.1 - 0.24 11.8 1.2 3.7 8.0 0.2 2.3 2 0 0 2 2 2 0 Styelin DUF373 PF04123.13 ABX13311.1 - 1.8e-92 310.4 11.2 2.1e-92 310.1 11.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF373) DUF4984 PF16372.5 ABX13311.1 - 0.016 15.2 0.1 0.025 14.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4984) Prenyltransf PF01255.19 ABX13312.1 - 1.4e-69 234.1 0.0 1.6e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase NUDIX PF00293.28 ABX13313.1 - 2.5e-20 72.8 0.6 2.9e-20 72.6 0.6 1.0 1 0 0 1 1 1 1 NUDIX domain Metallophos_3 PF14582.6 ABX13313.1 - 0.031 13.6 0.1 0.35 10.1 0.0 1.9 1 1 1 2 2 2 0 Metallophosphoesterase, calcineurin superfamily DUF3139 PF11337.8 ABX13313.1 - 0.14 12.8 1.6 0.22 12.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) OMPdecase PF00215.24 ABX13314.1 - 3.4e-26 92.2 0.0 4.2e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Adenylsucc_synt PF00709.21 ABX13316.1 - 4.8e-85 286.0 1.6 1.6e-41 142.6 0.0 3.0 1 1 2 3 3 3 3 Adenylosuccinate synthetase Annexin PF00191.20 ABX13317.1 - 0.0093 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Annexin Iron_traffic PF04362.14 ABX13318.1 - 6.9e-07 28.9 1.9 9.2e-07 28.5 1.9 1.5 1 1 0 1 1 1 1 Bacterial Fe(2+) trafficking zf_UBZ PF18439.1 ABX13318.1 - 0.16 11.6 2.9 0.29 10.7 0.3 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 ABX13318.1 - 0.3 10.9 0.3 0.3 10.9 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 ABX13320.1 - 0.024 14.6 3.8 0.27 11.2 3.8 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_S27e PF01667.17 ABX13320.1 - 0.24 11.2 3.5 0.6 9.9 3.5 1.6 1 1 0 1 1 1 0 Ribosomal protein S27 zf_C2H2_10 PF18414.1 ABX13320.1 - 1.2 8.7 5.1 1.3 8.6 0.9 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-ACC PF17848.1 ABX13320.1 - 1.3 9.2 7.6 5.2 7.2 2.4 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF3021 PF11457.8 ABX13321.1 - 2 8.7 20.8 1.9 8.8 9.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) HTH_45 PF14947.6 ABX13322.1 - 2.3e-11 43.5 0.1 2.9e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.7 ABX13322.1 - 3.7e-08 33.1 0.0 4.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 ABX13322.1 - 3.2e-05 23.7 0.0 4.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ABX13322.1 - 4.6e-05 23.1 0.0 5.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.22 ABX13322.1 - 0.00039 20.3 0.0 0.00054 19.8 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABX13322.1 - 0.00063 20.2 0.0 0.00077 19.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4364 PF14277.6 ABX13322.1 - 0.0011 18.7 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_24 PF13412.6 ABX13322.1 - 0.0017 17.9 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding RQC PF09382.10 ABX13322.1 - 0.0017 18.1 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 RQC domain Dimerisation2 PF16864.5 ABX13322.1 - 0.0022 18.0 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Dimerisation domain DUF1495 PF07381.11 ABX13322.1 - 0.0024 17.6 0.0 0.0034 17.2 0.0 1.4 1 1 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) RP-C PF03428.13 ABX13322.1 - 0.0029 17.3 0.0 0.0034 17.1 0.0 1.1 1 0 0 1 1 1 1 Replication protein C N-terminal domain DUF4194 PF13835.6 ABX13322.1 - 0.007 16.1 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4194) Mrr_N PF14338.6 ABX13322.1 - 0.0096 16.0 0.0 0.013 15.6 0.0 1.3 1 1 0 1 1 1 1 Mrr N-terminal domain Linker_histone PF00538.19 ABX13322.1 - 0.01 16.2 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 0 linker histone H1 and H5 family HTH_20 PF12840.7 ABX13322.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 ABX13322.1 - 0.018 14.9 0.1 0.026 14.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Rrf2 PF02082.20 ABX13322.1 - 0.021 15.2 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_34 PF13601.6 ABX13322.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain PadR PF03551.14 ABX13322.1 - 0.026 14.5 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family RPA_C PF08784.11 ABX13322.1 - 0.029 15.0 0.0 0.04 14.6 0.0 1.2 1 0 0 1 1 1 0 Replication protein A C terminal Replic_Relax PF13814.6 ABX13322.1 - 0.029 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation Cdc6_C PF09079.11 ABX13322.1 - 0.041 13.9 0.1 0.061 13.3 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain B-block_TFIIIC PF04182.12 ABX13322.1 - 0.049 13.8 0.1 0.066 13.4 0.1 1.1 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Ribosomal_S25 PF03297.15 ABX13322.1 - 0.055 13.7 0.1 0.063 13.5 0.1 1.2 1 0 0 1 1 1 0 S25 ribosomal protein RNA_pol_Rpc34 PF05158.12 ABX13322.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit DUF2250 PF10007.9 ABX13322.1 - 0.13 12.4 0.1 0.25 11.4 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) GBP_repeat PF02526.14 ABX13322.1 - 0.16 11.7 0.0 0.63 9.8 0.0 1.8 2 0 0 2 2 2 0 Glycophorin-binding protein Sua5_yciO_yrdC PF01300.18 ABX13323.1 - 2.5e-48 163.9 0.0 2.9e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination Carbam_trans_C PF16861.5 ABX13323.1 - 0.0075 15.9 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 2 Carbamoyltransferase C-terminus THUMP PF02926.17 ABX13324.1 - 2e-14 53.9 2.7 2.5e-14 53.6 2.7 1.1 1 0 0 1 1 1 1 THUMP domain Rep_fac_C PF08542.11 ABX13324.1 - 0.12 12.9 0.4 0.25 11.8 0.3 1.7 2 0 0 2 2 2 0 Replication factor C C-terminal domain ThiS PF02597.20 ABX13325.1 - 4.8e-10 39.9 0.2 2.1e-09 37.9 0.1 2.0 2 0 0 2 2 2 1 ThiS family CGI-121 PF08617.10 ABX13325.1 - 5.7e-06 26.5 3.9 9.1e-06 25.9 3.9 1.3 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Urm1 PF09138.11 ABX13325.1 - 4e-05 23.9 0.4 0.00017 21.9 0.4 2.1 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) HPHLAWLY PF14925.6 ABX13325.1 - 0.0019 17.0 1.1 0.0023 16.7 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF436 PF04260.12 ABX13325.1 - 0.069 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF436) Ribosomal_S17e PF00833.18 ABX13326.1 - 8.1e-25 87.1 1.5 8.9e-25 87.0 1.5 1.0 1 0 0 1 1 1 1 Ribosomal S17 TatD_DNase PF01026.21 ABX13327.1 - 2.5e-45 154.8 0.0 2.9e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_1 PF01979.20 ABX13327.1 - 0.14 11.5 0.3 0.3 10.4 0.3 1.6 1 1 0 1 1 1 0 Amidohydrolase family CBFD_NFYB_HMF PF00808.23 ABX13328.1 - 5.7e-13 48.9 0.1 7.1e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 ABX13328.1 - 0.0001 22.6 0.0 0.00012 22.4 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ABX13328.1 - 0.00031 20.8 0.1 0.00034 20.7 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 ABX13328.1 - 0.0056 17.0 0.1 0.0064 16.9 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 ABX13328.1 - 0.0067 16.5 0.0 0.0082 16.2 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ABX13328.1 - 0.024 14.6 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Bromodomain associated MU2_FHA PF18221.1 ABX13328.1 - 0.057 13.5 0.0 0.063 13.3 0.0 1.1 1 0 0 1 1 1 0 Mutator 2 Fork head associated domain TFIID_20kDa PF03847.13 ABX13328.1 - 0.075 13.5 0.0 0.087 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF2888 PF11135.8 ABX13330.1 - 0.087 12.8 0.1 0.67 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2888) PD40 PF07676.12 ABX13332.1 - 8.9e-12 44.6 1.3 0.15 12.0 0.0 6.1 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 ABX13332.1 - 2e-06 26.8 0.4 0.00058 18.7 0.0 3.8 3 1 1 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region MG2 PF01835.19 ABX13332.1 - 0.00081 19.8 0.0 0.012 16.0 0.0 2.3 2 0 0 2 2 2 1 MG2 domain DUF3244 PF11589.8 ABX13332.1 - 0.0054 16.8 2.0 0.0065 16.5 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3244) ANAPC4_WD40 PF12894.7 ABX13332.1 - 0.011 16.0 0.0 0.73 10.2 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Kelch_4 PF13418.6 ABX13333.1 - 0.12 12.5 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Galactose oxidase, central domain Redoxin PF08534.10 ABX13334.1 - 1.1e-10 41.3 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ABX13334.1 - 2e-07 30.9 0.0 0.0036 17.2 0.0 2.1 2 0 0 2 2 2 2 AhpC/TSA family DUF899 PF05988.12 ABX13334.1 - 0.0027 17.3 0.0 0.0029 17.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Glyoxalase PF00903.25 ABX13335.1 - 2.1e-10 40.9 0.0 2.7e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ABX13335.1 - 0.00023 21.1 0.2 0.0017 18.3 0.2 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ABX13335.1 - 0.0022 18.3 0.0 0.0034 17.7 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HATPase_c PF02518.26 ABX13336.1 - 1.5e-17 64.1 0.1 4e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABX13336.1 - 6.6e-12 45.3 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 ABX13336.1 - 1.4e-05 24.9 0.5 5.6e-05 23.0 0.5 2.0 1 0 0 1 1 1 1 GHKL domain dCache_1 PF02743.18 ABX13336.1 - 0.0013 18.6 4.8 0.0037 17.1 2.9 2.5 2 1 0 2 2 2 1 Cache domain HATPase_c_3 PF13589.6 ABX13336.1 - 0.12 12.2 1.7 0.18 11.6 0.0 2.1 3 0 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABX13336.1 - 0.15 12.0 0.0 0.57 10.2 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Baculo_11_kDa PF06143.11 ABX13336.1 - 0.32 10.6 3.6 1.4 8.6 0.3 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF3671 PF12420.8 ABX13336.1 - 4.2 7.5 6.9 3.4 7.8 1.7 2.7 2 1 0 2 2 2 0 Protein of unknown function Sigma_reg_N PF13800.6 ABX13337.1 - 9.8 6.5 8.4 15 5.9 0.1 3.0 2 1 1 3 3 3 0 Sigma factor regulator N-terminal Copper-bind PF00127.20 ABX13339.1 - 2.9e-07 30.9 0.0 1.1e-06 29.0 0.0 1.8 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX13339.1 - 1.3e-05 25.3 0.0 3.8e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Cupredoxin-like domain AIPR PF10592.9 ABX13340.1 - 3.4e-63 214.0 6.4 3.4e-63 214.0 6.4 2.1 2 1 0 2 2 2 1 AIPR protein FAM221 PF14753.6 ABX13341.1 - 0.0041 16.7 2.6 0.006 16.2 2.6 1.2 1 0 0 1 1 1 1 Protein FAM221A/B HTH_45 PF14947.6 ABX13342.1 - 1.9e-16 59.8 0.2 2.2e-16 59.6 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.6 ABX13342.1 - 0.0003 20.6 0.0 0.00036 20.3 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_34 PF13601.6 ABX13342.1 - 0.0011 19.2 0.1 0.0014 18.7 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.20 ABX13342.1 - 0.0025 18.1 0.1 0.0045 17.3 0.0 1.4 2 0 0 2 2 1 1 Transcriptional regulator RNA_pol_Rpc34 PF05158.12 ABX13342.1 - 0.0033 16.9 0.0 0.0034 16.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_27 PF13463.6 ABX13342.1 - 0.0046 17.4 0.0 0.0063 17.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 ABX13342.1 - 0.009 15.9 0.1 0.017 15.1 0.0 1.5 2 0 0 2 2 2 1 MarR family DUF505 PF04458.12 ABX13342.1 - 0.0095 14.4 0.0 0.0095 14.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF505) Mrr_N PF14338.6 ABX13342.1 - 0.017 15.2 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Mrr N-terminal domain PadR PF03551.14 ABX13342.1 - 0.027 14.4 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family B-block_TFIIIC PF04182.12 ABX13342.1 - 0.034 14.3 0.1 0.04 14.1 0.1 1.2 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC RPA_C PF08784.11 ABX13342.1 - 0.051 14.2 0.0 0.07 13.8 0.0 1.2 1 0 0 1 1 1 0 Replication protein A C terminal TrmB PF01978.19 ABX13342.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Mannosyl_trans2 PF04188.13 ABX13342.1 - 0.092 12.0 0.0 0.1 11.9 0.0 1.0 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) Ribosomal_S19e PF01090.19 ABX13342.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S19e PGM_PMM_I PF02878.16 ABX13343.1 - 6.5e-23 81.0 0.0 4.7e-22 78.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ABX13343.1 - 5.8e-15 55.5 0.0 1.3e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ABX13343.1 - 3.6e-14 53.2 0.0 9.3e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ABX13343.1 - 1.2e-07 31.8 0.1 3.3e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Glyco_transf_41 PF13844.6 ABX13343.1 - 0.024 13.1 0.3 0.039 12.4 0.3 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 AIRS PF00586.24 ABX13344.1 - 1.1e-14 54.9 0.0 1.8e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 ABX13344.1 - 4.7e-05 23.6 0.0 8.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain DUF4034 PF13226.6 ABX13345.1 - 0.00029 20.3 0.0 0.00031 20.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4034) Ribosomal_S11 PF00411.19 ABX13346.1 - 3e-33 114.5 1.5 3.5e-33 114.3 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 ABX13346.1 - 0.006 16.8 0.1 0.008 16.4 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) dsDNA_bind PF01984.20 ABX13348.1 - 4e-13 49.6 1.3 4.9e-13 49.3 1.3 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.9 ABX13348.1 - 0.017 15.5 0.9 0.032 14.7 0.9 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region RtcB PF01139.17 ABX13349.1 - 1.4e-164 548.2 0.2 1.6e-164 548.0 0.2 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Complex1_LYR PF05347.15 ABX13349.1 - 0.016 15.2 0.1 0.038 14.1 0.1 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF3492 PF11997.8 ABX13349.1 - 0.043 13.6 0.1 0.068 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) MBF1 PF08523.10 ABX13350.1 - 0.43 11.1 11.0 0.55 10.7 11.0 1.2 1 0 0 1 1 1 0 Multiprotein bridging factor 1 NEMP PF10225.9 ABX13350.1 - 0.66 9.6 1.4 0.63 9.7 1.4 1.1 1 0 0 1 1 1 0 NEMP family YqfQ PF14181.6 ABX13350.1 - 3.4 7.8 9.6 3.5 7.8 9.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein Borrelia_P83 PF05262.11 ABX13350.1 - 6.6 5.1 14.2 7.7 4.9 14.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Lyase_1 PF00206.20 ABX13351.1 - 9.6e-48 163.2 1.4 1.3e-47 162.8 1.4 1.1 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 ABX13351.1 - 5.4e-14 52.5 0.0 1.3e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 ABX13351.1 - 0.087 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal DM13 PF10517.9 ABX13352.1 - 2.8e-19 69.6 0.2 1.2e-18 67.5 0.1 2.0 2 0 0 2 2 2 1 Electron transfer DM13 MG2 PF01835.19 ABX13352.1 - 0.00038 20.9 0.0 0.00066 20.1 0.0 1.4 1 0 0 1 1 1 1 MG2 domain DUF771 PF05595.11 ABX13352.1 - 0.019 14.9 0.1 8 6.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF771) DUF1569 PF07606.11 ABX13352.1 - 0.068 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) Methyltransf_31 PF13847.6 ABX13353.1 - 2.7e-37 127.9 0.1 4.5e-37 127.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABX13353.1 - 2.6e-21 76.1 0.0 6.5e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABX13353.1 - 3.5e-21 75.8 0.0 8.6e-21 74.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABX13353.1 - 9.7e-21 74.4 0.0 1.7e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABX13353.1 - 4.7e-20 72.0 0.0 9.7e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABX13353.1 - 3.5e-11 42.9 0.1 1.3e-10 41.1 0.1 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 ABX13353.1 - 1.2e-10 41.1 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ABX13353.1 - 3.8e-09 36.3 0.0 6.3e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 ABX13353.1 - 1.2e-08 34.9 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 ABX13353.1 - 5e-08 32.6 0.0 1.9e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 ABX13353.1 - 1.7e-07 30.8 0.0 2.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 ABX13353.1 - 7.2e-06 25.3 0.0 4e-05 22.9 0.0 1.9 1 1 1 2 2 2 1 DREV methyltransferase PrmA PF06325.13 ABX13353.1 - 8.4e-06 25.4 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 ABX13353.1 - 1.3e-05 24.9 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 ABX13353.1 - 1.7e-05 24.5 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 ABX13353.1 - 3.1e-05 24.0 0.0 5.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 ABX13353.1 - 4.2e-05 23.3 0.0 6.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit TehB PF03848.14 ABX13353.1 - 8.7e-05 22.0 0.1 0.00014 21.3 0.1 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.18 ABX13353.1 - 9.2e-05 22.0 0.0 0.064 12.7 0.1 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain GidB PF02527.15 ABX13353.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_20 PF12147.8 ABX13353.1 - 0.00076 18.7 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.18 ABX13353.1 - 0.0032 17.2 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 ABX13353.1 - 0.0057 16.3 0.1 1.9 8.1 0.0 2.3 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase DUF938 PF06080.12 ABX13353.1 - 0.016 14.9 0.0 0.028 14.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Dimerisation2 PF16864.5 ABX13353.1 - 0.027 14.4 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain TPMT PF05724.11 ABX13353.1 - 0.027 14.1 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.7 ABX13353.1 - 0.03 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 ABX13353.1 - 0.033 13.1 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Spermine_synth PF01564.17 ABX13353.1 - 0.035 13.5 0.0 0.077 12.4 0.0 1.7 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Rrf2 PF02082.20 ABX13353.1 - 0.087 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator DUF5457 PF17540.2 ABX13353.1 - 0.099 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5457) Methyltransf_17 PF12692.7 ABX13353.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase DUF3139 PF11337.8 ABX13355.1 - 0.0077 16.9 0.1 0.014 16.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3139) Prominin PF05478.11 ABX13355.1 - 0.012 13.6 0.1 0.014 13.4 0.1 1.0 1 0 0 1 1 1 0 Prominin PPO1_DWL PF12142.8 ABX13355.1 - 0.082 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Trypan_PARP PF05887.11 ABX13357.1 - 0.036 14.0 0.3 0.058 13.4 0.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glyoxalase_6 PF18029.1 ABX13359.1 - 8e-05 23.4 0.0 0.00011 22.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 ABX13359.1 - 0.0013 19.0 0.1 0.0073 16.5 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zinc_ribbon_10 PF10058.9 ABX13360.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Asn_synthase PF00733.21 ABX13362.1 - 8.1e-26 91.5 0.0 2.8e-20 73.3 0.0 2.0 1 1 1 2 2 2 2 Asparagine synthase NAD_synthase PF02540.17 ABX13362.1 - 4.3e-05 22.7 0.2 0.00012 21.3 0.0 1.8 2 0 0 2 2 2 1 NAD synthase QueC PF06508.13 ABX13362.1 - 0.00035 20.1 0.0 0.00065 19.3 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 ABX13362.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.9 2 1 0 2 2 2 0 PP-loop family DnaB_bind PF10410.9 ABX13362.1 - 0.09 13.0 0.0 0.76 10.0 0.0 2.3 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase SNase PF00565.17 ABX13363.1 - 3.3e-10 40.4 0.0 6.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Excalibur PF05901.11 ABX13363.1 - 0.00064 20.3 0.7 0.0016 19.0 0.7 1.7 1 0 0 1 1 1 1 Excalibur calcium-binding domain Ly49 PF08391.10 ABX13363.1 - 0.1 13.0 0.2 0.19 12.1 0.2 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Pterin_4a PF01329.19 ABX13364.1 - 9.3e-31 105.9 0.0 1e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase PTPS PF01242.19 ABX13365.1 - 3.6e-19 68.9 0.5 4.2e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 6-pyruvoyl tetrahydropterin synthase Sigma70_r4_2 PF08281.12 ABX13366.1 - 0.0014 18.2 0.0 0.0046 16.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 UPF0122 PF04297.14 ABX13366.1 - 0.0022 18.2 0.1 0.0053 17.0 0.1 1.7 1 1 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_23 PF13384.6 ABX13366.1 - 0.0097 15.7 0.0 0.035 13.9 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain PPL4 PF18188.1 ABX13366.1 - 0.014 15.4 3.5 0.026 14.5 2.8 1.8 1 1 1 2 2 2 0 Prim-pol 4 Sigma70_r4 PF04545.16 ABX13366.1 - 0.025 14.1 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3399 PF11879.8 ABX13366.1 - 0.039 14.3 0.0 0.063 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) dCMP_cyt_deam_1 PF00383.23 ABX13367.1 - 2e-14 53.3 0.2 2.3e-14 53.1 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ABX13367.1 - 0.033 13.9 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 MafB19-like deaminase LmjF365940-deam PF14421.6 ABX13367.1 - 0.15 11.6 0.9 1 8.9 0.2 1.8 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases SNAD4 PF18750.1 ABX13367.1 - 0.16 12.1 0.1 0.23 11.6 0.1 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 HEAT_2 PF13646.6 ABX13368.1 - 4e-05 23.9 0.0 0.0043 17.4 0.0 3.1 1 1 1 2 2 2 1 HEAT repeats AAA_5 PF07728.14 ABX13368.1 - 0.00011 22.2 0.1 0.00044 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 ABX13368.1 - 0.00025 20.6 0.0 0.00056 19.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 ABX13368.1 - 0.00085 19.7 0.4 0.012 16.0 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF2161 PF09929.9 ABX13368.1 - 0.0051 16.9 0.3 0.014 15.5 0.1 1.9 2 0 0 2 2 2 1 Putative PD-(D/E)XK phosphodiesterase (DUF2161) ZapD PF07072.11 ABX13368.1 - 0.013 15.3 1.7 6.4 6.5 0.0 3.3 2 1 1 3 3 3 0 Cell division protein AAA_22 PF13401.6 ABX13368.1 - 0.024 14.9 0.1 0.16 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ABX13368.1 - 0.025 14.5 0.0 0.079 12.9 0.0 1.9 1 1 0 1 1 1 0 NACHT domain RNase_H2-Ydr279 PF09468.10 ABX13368.1 - 0.041 14.1 1.4 4 7.6 0.5 3.2 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain AAA_30 PF13604.6 ABX13368.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 ABX13368.1 - 0.08 13.0 0.3 0.08 13.0 0.3 3.9 4 0 0 4 4 4 0 Helicase HerA, central domain Imm32 PF15566.6 ABX13368.1 - 0.12 12.2 0.5 0.46 10.3 0.1 2.3 2 0 0 2 2 2 0 Immunity protein 32 AAA_24 PF13479.6 ABX13368.1 - 0.39 10.4 3.5 2.1 8.0 0.1 3.3 4 0 0 4 4 4 0 AAA domain DNA_methylase PF00145.17 ABX13369.1 - 3.3e-66 223.9 0.8 3.8e-66 223.7 0.8 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Cons_hypoth95 PF03602.15 ABX13369.1 - 3.6e-05 23.5 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 ABX13369.1 - 0.00043 19.9 0.1 0.00093 18.8 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Tox-HDC PF15656.6 ABX13369.1 - 0.026 14.7 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature PrmA PF06325.13 ABX13369.1 - 0.045 13.1 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Curto_V2 PF07325.11 ABX13369.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Curtovirus V2 protein ARL2_Bind_BART PF11527.8 ABX13370.1 - 0.15 12.2 3.3 0.28 11.3 2.2 2.1 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART RNA_helicase PF00910.22 ABX13371.1 - 0.00048 20.5 0.3 0.01 16.2 0.0 2.9 3 0 0 3 3 3 1 RNA helicase AAA_14 PF13173.6 ABX13371.1 - 0.016 15.3 1.1 0.26 11.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ABX13371.1 - 0.022 15.1 0.1 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ABX13371.1 - 0.034 14.4 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ABX13371.1 - 0.038 13.5 0.1 0.12 11.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 ABX13371.1 - 0.061 13.3 0.0 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRCR_2 PF15494.6 ABX13371.1 - 0.12 12.9 0.1 0.36 11.4 0.1 1.7 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain tRNA-synt_1 PF00133.22 ABX13373.1 - 6.9e-106 354.9 0.2 1.1e-104 350.8 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ABX13373.1 - 3.7e-33 114.6 5.0 4.3e-33 114.4 2.9 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ABX13373.1 - 2.4e-19 69.4 0.8 2.1e-09 36.7 0.0 3.5 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ABX13373.1 - 2.3e-05 24.0 0.7 0.0041 16.7 0.0 3.2 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 ABX13373.1 - 0.054 12.8 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain SNO PF01174.19 ABX13374.1 - 2e-47 161.5 0.2 2.3e-47 161.3 0.2 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase PF00117.28 ABX13374.1 - 1.3e-12 47.8 0.0 2.3e-12 47.1 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 ABX13374.1 - 8.1e-12 45.2 0.0 1.4e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 ABX13374.1 - 4.4e-06 26.6 0.2 8.3e-06 25.7 0.2 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 ABX13374.1 - 1.7e-05 24.5 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 Peptidase_C26 PF07722.13 ABX13374.1 - 0.00013 21.8 0.0 0.0015 18.3 0.0 2.2 2 1 0 2 2 2 1 Peptidase C26 BPL_N PF09825.9 ABX13374.1 - 0.0065 15.6 0.0 0.31 10.1 0.0 2.2 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal SOR_SNZ PF01680.17 ABX13375.1 - 2.6e-95 318.1 5.2 2.6e-95 318.1 5.2 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 ABX13375.1 - 2.3e-07 30.4 5.7 5.7e-06 25.8 0.9 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 ABX13375.1 - 0.00034 20.2 0.8 0.05 13.1 0.1 3.1 2 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 ABX13375.1 - 0.00063 19.2 4.8 0.037 13.4 0.2 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase Dus PF01207.17 ABX13375.1 - 0.0013 17.9 0.5 1.1 8.3 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.21 ABX13375.1 - 0.0021 17.3 0.0 0.065 12.4 0.0 2.4 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase OMPdecase PF00215.24 ABX13375.1 - 0.0089 15.6 1.5 0.65 9.6 0.1 2.5 2 1 1 3 3 3 2 Orotidine 5'-phosphate decarboxylase / HUMPS family NanE PF04131.14 ABX13375.1 - 0.052 12.7 2.9 0.52 9.5 0.0 3.0 2 2 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Peptidase_S66C PF17676.1 ABX13375.1 - 0.076 13.6 0.0 0.24 12.0 0.0 1.9 2 0 0 2 2 2 0 LD-carboxypeptidase C-terminal domain PA PF02225.22 ABX13375.1 - 0.14 12.2 0.5 5.6 7.1 0.1 2.4 2 0 0 2 2 2 0 PA domain AHD PF17793.1 ABX13376.1 - 0.009 15.8 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 ANC1 homology domain (AHD) TubC_N PF18563.1 ABX13376.1 - 0.12 12.4 0.7 0.27 11.3 0.2 1.8 2 0 0 2 2 2 0 TubC N-terminal docking domain CBS PF00571.28 ABX13377.1 - 2.2e-36 124.1 7.0 8.6e-10 38.9 0.1 4.2 4 0 0 4 4 4 4 CBS domain Peptidase_S7 PF00949.21 ABX13377.1 - 0.086 12.7 0.6 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Aconitase PF00330.20 ABX13378.1 - 5e-144 480.7 0.0 7e-144 480.3 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ABX13378.1 - 1.5e-37 128.9 0.1 6.8e-37 126.7 0.0 2.0 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF521 PF04412.13 ABX13378.1 - 0.054 12.2 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) F-box-like_2 PF13013.6 ABX13379.1 - 0.019 14.9 0.8 0.28 11.2 0.8 2.1 1 1 0 1 1 1 0 F-box-like domain COesterase PF00135.28 ABX13380.1 - 0.045 12.6 1.5 0.05 12.5 1.5 1.1 1 0 0 1 1 1 0 Carboxylesterase family AsnC_trans_reg PF01037.21 ABX13381.1 - 1.2e-10 41.2 0.0 1.4e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 ABX13381.1 - 0.0014 18.7 0.0 0.0016 18.5 0.0 1.1 1 0 0 1 1 1 1 NapD protein EVE PF01878.18 ABX13382.1 - 3.1e-40 137.5 0.6 3.5e-40 137.3 0.6 1.0 1 0 0 1 1 1 1 EVE domain HP1451_C PF18472.1 ABX13382.1 - 0.014 15.4 0.1 0.033 14.2 0.0 1.6 2 0 0 2 2 2 0 HP1451 C-terminal domain DUF1175 PF06672.11 ABX13382.1 - 0.061 13.0 0.1 0.25 11.0 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) Neurensin PF14927.6 ABX13383.1 - 0.00082 19.1 0.2 0.00099 18.8 0.2 1.0 1 0 0 1 1 1 1 Neurensin DUF308 PF03729.13 ABX13383.1 - 0.003 17.8 4.8 0.74 10.2 0.9 2.1 2 0 0 2 2 2 2 Short repeat of unknown function (DUF308) DUF3185 PF11381.8 ABX13383.1 - 0.017 15.1 6.7 0.19 11.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF2157 PF09925.9 ABX13383.1 - 0.16 11.7 1.3 7.1 6.4 0.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) PIRT PF15099.6 ABX13383.1 - 0.81 9.3 3.1 2.3 7.8 0.0 2.0 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family Saf_2TM PF18303.1 ABX13383.1 - 5 6.7 7.9 2.9 7.4 3.2 2.0 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF3899 PF13038.6 ABX13383.1 - 5.1 7.7 7.7 6.5 7.3 4.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) tRNA_synthFbeta PF17759.1 ABX13384.1 - 4.5e-39 134.1 0.0 2.6e-38 131.6 0.0 1.9 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 ABX13384.1 - 2.6e-18 66.1 0.0 7e-12 45.5 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetase B5 domain B3_4 PF03483.17 ABX13384.1 - 1.3e-13 51.0 0.7 2.7e-13 50.0 0.4 1.6 2 0 0 2 2 2 1 B3/4 domain AHJR-like PF18743.1 ABX13384.1 - 0.087 12.4 0.1 0.66 9.5 0.0 2.4 3 0 0 3 3 3 0 REase_AHJR-like tRNA-synt_2d PF01409.20 ABX13385.1 - 2.3e-83 279.4 0.0 2.9e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 ABX13385.1 - 1.2e-05 24.8 0.0 0.0013 18.2 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 ABX13385.1 - 0.0062 15.7 0.3 0.02 14.0 0.0 1.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 ABX13385.1 - 0.01 15.8 0.0 0.038 14.0 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) HTH_9 PF08221.11 ABX13385.1 - 0.027 14.5 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain tRNA-synt_1b PF00579.25 ABX13386.1 - 4.6e-30 104.9 0.0 8e-30 104.2 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 ABX13386.1 - 0.008 15.1 0.0 0.14 11.0 0.0 2.6 2 1 1 3 3 3 1 tRNA synthetases class I (K) CdAMP_rec PF06153.11 ABX13387.1 - 0.013 15.7 0.1 0.017 15.3 0.1 1.4 1 1 0 1 1 1 0 Cyclic-di-AMP receptor Sial-lect-inser PF09264.10 ABX13387.1 - 0.015 15.0 0.2 0.015 15.0 0.2 1.1 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion zf-UBR PF02207.20 ABX13388.1 - 8e-05 22.7 12.8 0.02 15.1 0.8 3.2 4 0 0 4 4 4 2 Putative zinc finger in N-recognin (UBR box) zf-RING_14 PF17978.1 ABX13388.1 - 0.0076 16.6 5.1 1.1 9.8 0.2 3.2 3 0 0 3 3 3 2 RING/Ubox like zinc-binding domain zinc_ribbon_6 PF14599.6 ABX13388.1 - 0.34 11.0 24.3 1.6 8.8 0.3 5.3 4 2 2 6 6 6 0 Zinc-ribbon DUF866 PF05907.13 ABX13388.1 - 2.3 8.1 6.4 14 5.6 0.4 2.9 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF866) OrfB_Zn_ribbon PF07282.11 ABX13388.1 - 6.7 6.7 14.1 33 4.5 1.8 3.8 3 0 0 3 3 3 0 Putative transposase DNA-binding domain CTP_transf_like PF01467.26 ABX13390.1 - 8.5e-14 51.9 0.0 1.2e-13 51.4 0.0 1.3 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 ABX13390.1 - 0.0029 17.5 0.0 0.008 16.1 0.0 1.7 2 0 0 2 2 2 1 FAD synthetase AhpC-TSA PF00578.21 ABX13392.1 - 2.5e-19 69.4 0.1 3.1e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ABX13392.1 - 7.4e-15 54.9 0.1 9.1e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 ABX13392.1 - 6.8e-06 26.3 0.1 1.1e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ABX13392.1 - 0.00071 20.0 0.2 0.0012 19.3 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 ABX13392.1 - 0.0022 18.0 0.4 0.092 12.8 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin domain T4_deiodinase PF00837.17 ABX13392.1 - 0.04 13.2 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase TraF PF13728.6 ABX13392.1 - 0.084 12.7 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein TPM_phosphatase PF04536.14 ABX13392.1 - 0.096 12.9 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 TPM domain B12-binding_2 PF02607.17 ABX13393.1 - 0.00017 22.0 0.0 0.00036 20.9 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain GntR PF00392.21 ABX13393.1 - 0.018 14.7 1.2 1.1 8.9 0.1 3.1 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ABX13393.1 - 0.027 14.0 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 ABX13393.1 - 0.042 13.9 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix CtsR_C PF17727.1 ABX13393.1 - 0.071 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain HTH_11 PF08279.12 ABX13393.1 - 0.073 13.0 0.5 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 HTH domain HTH_IclR PF09339.10 ABX13393.1 - 0.12 12.2 0.0 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain Lectin_like PF18560.1 ABX13394.1 - 0.0061 16.7 0.1 0.0076 16.4 0.1 1.1 1 0 0 1 1 1 1 Lectin like domain PI3K_P85_iSH2 PF16454.5 ABX13394.1 - 0.041 13.5 0.4 0.055 13.1 0.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain LOH1CR12 PF10158.9 ABX13394.1 - 0.076 13.0 0.3 0.24 11.4 0.3 1.9 1 1 1 2 2 2 0 Tumour suppressor protein MethyltransfD12 PF02086.15 ABX13395.1 - 4.3e-65 220.0 1.4 4.9e-65 219.8 1.4 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase DUF2089 PF09862.9 ABX13395.1 - 0.00053 20.0 0.1 0.0012 18.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) Cons_hypoth95 PF03602.15 ABX13395.1 - 0.075 12.7 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 DNA_photolyase PF00875.18 ABX13395.1 - 0.08 12.9 0.0 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 DNA photolyase Pico_P2A PF00947.19 ABX13395.1 - 0.086 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Picornavirus core protein 2A Archaeal_AmoA PF12942.7 ABX13396.1 - 5.5e-115 381.5 16.6 6.6e-115 381.2 16.6 1.1 1 0 0 1 1 1 1 Archaeal ammonia monooxygenase subunit A (AmoA) Gram_pos_anchor PF00746.21 ABX13397.1 - 5.2 7.1 5.2 14 5.7 0.9 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif AmoC PF04896.12 ABX13398.1 - 6.5e-13 48.5 6.4 8.3e-13 48.2 6.4 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C RTA1 PF04479.13 ABX13398.1 - 0.0051 16.4 0.3 0.0078 15.8 0.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Monooxygenase_B PF04744.12 ABX13399.1 - 6.9e-08 31.7 0.1 1.6e-07 30.5 0.1 1.6 1 1 0 1 1 1 1 Monooxygenase subunit B protein FixQ PF05545.11 ABX13402.1 - 0.058 13.4 1.5 0.093 12.7 1.5 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ LapA_dom PF06305.11 ABX13403.1 - 0.061 13.1 1.4 6.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Folate_carrier PF01770.18 ABX13403.1 - 0.54 8.9 1.2 2.7 6.6 1.2 1.8 1 1 0 1 1 1 0 Reduced folate carrier Ribosomal_S13_N PF08069.12 ABX13404.1 - 1.5e-26 92.2 0.4 2.8e-26 91.3 0.4 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 ABX13404.1 - 2.2e-10 40.6 0.3 3.5e-10 39.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Nnf1 PF03980.14 ABX13404.1 - 0.1 13.0 0.8 0.16 12.4 0.3 1.5 2 0 0 2 2 2 0 Nnf1 DHHA1 PF02272.19 ABX13405.1 - 7.5e-13 49.1 0.0 2e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 ABX13405.1 - 0.0087 16.3 0.1 0.018 15.3 0.1 1.5 1 0 0 1 1 1 1 DHH family Pcc1 PF09341.10 ABX13406.1 - 2.6e-06 27.5 0.0 3.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF4854 PF16146.5 ABX13406.1 - 0.00089 19.6 0.1 0.0011 19.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4854) DUF2806 PF10987.8 ABX13406.1 - 0.036 13.9 0.1 0.04 13.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) tRNA-synt_2b PF00587.25 ABX13407.1 - 7.5e-36 123.8 0.5 1.3e-35 122.9 0.5 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ABX13407.1 - 4.8e-26 91.1 6.5 9.3e-26 90.2 6.5 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 ABX13407.1 - 0.084 13.3 0.2 0.28 11.6 0.2 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TSP_NTD PF17804.1 ABX13407.1 - 0.9 9.8 6.3 0.45 10.7 3.1 2.1 2 0 0 2 2 2 0 Tail specific protease N-terminal domain APG6_N PF17675.1 ABX13407.1 - 2.6 8.6 8.6 1.8 9.1 3.3 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region M PF02370.16 ABX13407.1 - 7.7 7.5 8.1 12 6.8 1.8 3.4 2 1 1 3 3 3 0 M protein repeat Ribosomal_S3Ae PF01015.18 ABX13408.1 - 2.8e-61 206.6 3.3 3.2e-61 206.4 3.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family RNA_binding PF01877.17 ABX13409.1 - 9e-30 103.4 5.4 1.1e-29 103.1 5.4 1.1 1 0 0 1 1 1 1 RNA binding HD_3 PF13023.6 ABX13409.1 - 0.0066 16.4 1.1 0.01 15.8 0.5 1.6 1 1 1 2 2 2 1 HD domain FAD_binding_2 PF00890.24 ABX13410.1 - 5.5e-08 32.3 0.2 6.8e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 ABX13410.1 - 7.8e-06 25.5 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ABX13410.1 - 2.1e-05 23.6 0.3 0.002 17.1 0.2 2.1 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 ABX13410.1 - 4.6e-05 23.2 0.2 0.096 12.2 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABX13410.1 - 0.00017 20.9 0.3 0.002 17.4 0.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABX13410.1 - 0.0015 17.9 0.1 0.38 9.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 ABX13410.1 - 0.019 15.5 0.5 2.8 8.6 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABX13410.1 - 0.033 12.9 0.2 0.67 8.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 ABX13410.1 - 0.048 12.9 0.0 0.54 9.5 0.0 2.5 3 0 0 3 3 3 0 Thi4 family Lycopene_cycl PF05834.12 ABX13410.1 - 0.054 12.5 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 ABX13410.1 - 0.096 12.9 0.0 0.35 11.1 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GDI PF00996.18 ABX13410.1 - 0.099 11.1 0.0 0.25 9.8 0.0 1.6 2 0 0 2 2 2 0 GDP dissociation inhibitor AAA_5 PF07728.14 ABX13411.1 - 5.1e-23 81.6 0.0 8.1e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ABX13411.1 - 1.8e-12 47.2 0.0 2.6e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 ABX13411.1 - 1.9e-07 31.6 0.0 3.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ABX13411.1 - 1.6e-05 24.7 0.1 3.8e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 ABX13411.1 - 5.5e-05 23.6 0.4 0.0001 22.8 0.1 1.8 2 1 0 2 2 1 1 AAA ATPase domain AAA_6 PF12774.7 ABX13411.1 - 5.9e-05 22.2 0.0 0.00039 19.5 0.0 2.0 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_14 PF13173.6 ABX13411.1 - 0.0001 22.4 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ABX13411.1 - 0.00012 21.7 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region CbbQ_C PF08406.10 ABX13411.1 - 0.00045 20.4 0.0 0.00083 19.6 0.0 1.4 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal AAA_22 PF13401.6 ABX13411.1 - 0.0018 18.5 0.2 0.0035 17.6 0.2 1.6 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ABX13411.1 - 0.0023 17.9 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RuvB_N PF05496.12 ABX13411.1 - 0.0026 17.5 0.6 0.15 11.8 0.2 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 ABX13411.1 - 0.0028 17.8 0.0 0.0082 16.3 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 ABX13411.1 - 0.0037 16.7 0.0 0.74 9.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ABX13411.1 - 0.0071 16.3 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 ABX13411.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ABX13411.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 ABX13411.1 - 0.024 15.2 0.0 0.056 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABX13411.1 - 0.03 14.6 0.3 0.065 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 ABX13411.1 - 0.03 14.5 0.1 0.058 13.6 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 ABX13411.1 - 0.033 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 ABX13411.1 - 0.047 13.4 0.3 0.11 12.2 0.2 1.8 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 ABX13411.1 - 0.066 12.6 0.1 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 ABX13411.1 - 0.12 12.6 0.1 0.42 10.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABX13411.1 - 0.12 12.1 0.9 0.48 10.1 0.2 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ABX13411.1 - 0.16 12.5 0.3 0.23 12.0 0.3 1.8 1 1 0 1 1 1 0 ABC transporter VWA PF00092.28 ABX13412.1 - 9.4e-07 29.2 0.0 2.4e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 ABX13412.1 - 0.00087 19.3 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ABX13412.1 - 0.0019 18.8 0.0 0.005 17.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain PALP PF00291.25 ABX13413.1 - 1e-24 87.5 0.5 5.5e-22 78.5 0.1 3.4 2 1 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme TIP49 PF06068.13 ABX13413.1 - 0.0072 15.6 0.1 0.017 14.3 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain ASCH PF04266.14 ABX13414.1 - 1.6e-11 44.7 0.1 2.3e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 ASCH domain TBP PF00352.21 ABX13415.1 - 2.5e-54 181.2 0.1 1.8e-27 95.1 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 ABX13415.1 - 8.1e-06 25.9 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) PAS_11 PF14598.6 ABX13415.1 - 0.017 15.3 0.0 5.9 7.1 0.0 2.2 2 0 0 2 2 2 0 PAS domain NERD PF08378.11 ABX13417.1 - 0.031 14.7 2.0 0.26 11.8 0.2 2.2 1 1 0 2 2 2 0 Nuclease-related domain FlgD_ig PF13860.6 ABX13418.1 - 0.0044 16.9 0.4 0.019 14.8 0.4 1.9 1 1 0 1 1 1 1 FlgD Ig-like domain Pilin_N PF07790.11 ABX13418.1 - 0.17 12.8 3.3 0.69 10.9 3.3 2.0 1 1 0 1 1 1 0 Archaeal Type IV pilin, N-terminal P-II PF00543.22 ABX13419.1 - 1.9e-11 44.5 2.3 2.1e-11 44.3 2.3 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II AsnC_trans_reg PF01037.21 ABX13420.1 - 8.7e-13 48.0 0.0 1e-12 47.8 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 ABX13420.1 - 0.00054 20.0 0.1 0.00064 19.7 0.1 1.1 1 0 0 1 1 1 1 NapD protein Dus PF01207.17 ABX13421.1 - 6.2e-74 248.9 0.0 7.4e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 ABX13421.1 - 4.4e-07 29.4 0.0 8.5e-05 21.9 0.0 2.1 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.14 ABX13421.1 - 3e-05 23.3 0.0 0.00013 21.2 0.0 1.9 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Oxidored_FMN PF00724.20 ABX13421.1 - 0.00035 19.9 0.0 0.00054 19.3 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 ABX13421.1 - 0.0022 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein MR_MLE_C PF13378.6 ABX13421.1 - 0.011 15.3 0.0 0.04 13.5 0.0 1.8 1 1 1 2 2 2 0 Enolase C-terminal domain-like FMN_dh PF01070.18 ABX13421.1 - 0.05 12.6 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NIR_SIR_ferr PF03460.17 ABX13421.1 - 0.059 13.2 0.3 0.31 10.9 0.0 2.3 3 0 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain IMPDH PF00478.25 ABX13421.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.3 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF3198 PF11433.8 ABX13421.1 - 0.12 12.3 0.3 0.12 12.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) B12-binding PF02310.19 ABX13421.1 - 0.17 12.0 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain TSP_3 PF02412.18 ABX13422.1 - 1.2e-28 98.4 205.2 0.0021 17.7 2.7 26.1 25 7 1 27 27 27 16 Thrombospondin type 3 repeat DUF282 PF03380.14 ABX13422.1 - 0.097 12.6 18.7 44 4.1 0.0 9.4 9 0 0 9 9 9 0 Caenorhabditis protein of unknown function, DUF282 MRP-S26 PF14943.6 ABX13422.1 - 0.16 11.9 0.7 32 4.4 0.1 3.6 3 0 0 3 3 3 0 Mitochondrial ribosome subunit S26 DUF543 PF04418.12 ABX13422.1 - 0.33 11.0 0.8 98 3.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF543) TSP_3 PF02412.18 ABX13423.1 - 3.7e-39 132.1 193.5 0.00032 20.3 0.5 26.2 22 8 5 27 27 27 16 Thrombospondin type 3 repeat SAPI PF16560.5 ABX13423.1 - 0.0045 16.6 1.9 11 5.6 0.1 3.3 3 0 0 3 3 3 3 Putative mobile pathogenicity island TcdB_toxin_midN PF12256.8 ABX13423.1 - 9.5 5.6 10.6 42 3.4 0.0 6.0 6 1 1 7 7 7 0 Insecticide toxin TcdB middle/N-terminal region TSP_3 PF02412.18 ABX13424.1 - 1.3e-34 117.5 265.9 0.002 17.7 3.0 28.1 24 13 2 26 26 26 19 Thrombospondin type 3 repeat CBP PF12192.8 ABX13424.1 - 0.074 13.3 0.0 48 4.3 0.0 4.9 5 0 0 5 5 5 0 Fungal calcium binding protein DUF282 PF03380.14 ABX13424.1 - 3.1 7.8 22.5 5.4 7.0 0.2 8.0 10 0 0 10 10 10 0 Caenorhabditis protein of unknown function, DUF282 Wyosine_form PF08608.12 ABX13425.1 - 1.2e-19 70.4 0.1 8.1e-19 67.7 0.1 2.2 2 0 0 2 2 2 1 Wyosine base formation Radical_SAM PF04055.21 ABX13425.1 - 2.8e-18 66.8 0.0 1.3e-17 64.7 0.0 2.0 2 1 0 2 2 2 1 Radical SAM superfamily IMP_cyclohyd PF07826.11 ABX13425.1 - 0.004 16.8 0.0 0.0081 15.8 0.0 1.6 1 1 0 1 1 1 1 IMP cyclohydrolase-like protein Ham1p_like PF01725.16 ABX13426.1 - 8e-43 146.5 0.0 9e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family JLPA PF16668.5 ABX13426.1 - 0.0017 17.5 0.2 0.0028 16.8 0.2 1.4 1 1 0 1 1 1 1 Adhesin from Campylobacter Torsin PF06309.11 ABX13426.1 - 0.008 16.3 0.0 0.018 15.1 0.0 1.6 1 1 0 1 1 1 1 Torsin Pkinase PF00069.25 ABX13427.1 - 4.1e-10 39.5 1.6 5e-10 39.2 1.6 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 ABX13427.1 - 5e-10 39.3 0.1 6.9e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 ABX13427.1 - 5.9e-07 29.1 0.0 8.7e-06 25.2 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 ABX13427.1 - 1.6e-05 24.3 0.1 2.4e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ABX13427.1 - 6.4e-05 23.0 0.0 0.00059 19.8 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ABX13427.1 - 0.006 15.5 0.2 0.0093 14.9 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) WaaY PF06176.11 ABX13427.1 - 0.0078 15.9 0.2 0.015 14.9 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Peptidase_M22 PF00814.25 ABX13429.1 - 8.6e-74 248.6 0.0 1e-73 248.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family ATPgrasp_N PF18130.1 ABX13429.1 - 0.17 12.5 0.0 0.43 11.2 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp N-terminal domain MMR_HSR1_C PF08438.10 ABX13430.1 - 2.8e-28 98.7 0.0 7.1e-28 97.4 0.0 1.7 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 ABX13430.1 - 1.9e-20 73.0 0.1 5.4e-19 68.4 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 ABX13430.1 - 2.5e-10 40.2 0.1 6e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 ABX13430.1 - 6.4e-06 25.8 0.1 2.4e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B YchF-GTPase_C PF06071.13 ABX13430.1 - 0.002 18.3 0.0 0.0069 16.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) AAA_18 PF13238.6 ABX13431.1 - 4.5e-15 56.3 0.5 7.2e-15 55.7 0.5 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 ABX13431.1 - 2.4e-07 31.0 0.3 4.8e-06 26.8 0.3 2.2 1 1 0 1 1 1 1 Cytidylate kinase-like family SKI PF01202.22 ABX13431.1 - 5.8e-05 23.3 0.3 9.2e-05 22.6 0.3 1.6 1 1 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.6 ABX13431.1 - 0.00047 20.6 0.0 0.00085 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 ABX13431.1 - 0.00062 19.3 0.3 0.0011 18.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA PF00004.29 ABX13431.1 - 0.0016 18.9 0.0 0.0032 17.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ABX13431.1 - 0.0026 18.0 0.0 0.0055 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ABX13431.1 - 0.0078 16.2 0.3 0.056 13.5 0.3 2.1 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ABX13431.1 - 0.011 15.6 3.0 0.028 14.3 2.6 2.2 1 1 0 1 1 1 0 NTPase Cytidylate_kin PF02224.18 ABX13431.1 - 0.017 14.9 0.0 0.033 13.9 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase CoaE PF01121.20 ABX13431.1 - 0.022 14.4 0.1 0.077 12.7 0.0 1.9 1 1 1 2 2 2 0 Dephospho-CoA kinase AAA_33 PF13671.6 ABX13431.1 - 0.024 14.8 0.0 0.027 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ABX13431.1 - 0.052 13.8 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ABX13431.1 - 0.13 11.2 0.9 0.54 9.2 0.3 2.1 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TGT PF01702.18 ABX13432.1 - 2.5e-67 227.5 0.0 4.9e-67 226.5 0.0 1.4 2 0 0 2 2 2 1 Queuine tRNA-ribosyltransferase DUF5591 PF17884.1 ABX13432.1 - 3.1e-09 36.9 0.1 5.9e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5591) Fer4 PF00037.27 ABX13433.1 - 2e-11 43.2 10.3 7.8e-06 25.5 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 ABX13433.1 - 4.5e-09 36.7 3.2 6.5e-09 36.2 3.2 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABX13433.1 - 8.1e-09 35.2 7.3 7.8e-05 22.6 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 ABX13433.1 - 1.2e-08 34.9 1.5 1.7e-08 34.4 1.5 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 ABX13433.1 - 1.2e-06 28.2 8.3 0.0014 18.6 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 ABX13433.1 - 2.8e-06 27.8 4.5 0.0042 17.6 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_10 PF13237.6 ABX13433.1 - 1.2e-05 25.3 8.0 0.00027 21.0 8.6 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ABX13433.1 - 1.5e-05 25.0 4.6 8.9e-05 22.6 4.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 ABX13433.1 - 8.6e-05 22.7 7.5 0.022 15.2 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 ABX13433.1 - 0.00017 22.5 3.3 0.31 12.0 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 ABX13433.1 - 0.00099 19.9 2.5 0.43 11.4 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 ABX13433.1 - 0.0019 18.9 10.5 0.0072 17.0 2.6 2.3 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_8 PF13183.6 ABX13433.1 - 0.0019 18.6 5.4 0.02 15.4 5.5 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 ABX13433.1 - 0.0032 18.3 10.4 0.098 13.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 ABX13433.1 - 0.028 15.0 7.5 1.2 9.7 7.6 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 ABX13433.1 - 0.59 10.3 9.7 1.4 9.2 2.5 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain RMMBL PF07521.12 ABX13435.1 - 6e-16 58.1 0.0 1.4e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 ABX13435.1 - 6.3e-16 58.6 0.0 1.1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 ABX13435.1 - 1.6e-10 40.7 0.0 3.8e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 ABX13435.1 - 2.8e-10 40.1 0.0 5.3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ABX13435.1 - 1.3e-09 38.4 1.3 1.9e-08 34.6 1.0 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 ABX13435.1 - 4.9e-06 26.5 0.0 2.2e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 ABX13435.1 - 0.00056 19.2 0.0 0.0014 17.9 0.0 1.7 1 1 0 1 1 1 1 Putative beta-lactamase-like family HhH-GPD PF00730.25 ABX13436.1 - 4.5e-12 46.4 0.1 8e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein OGG_N PF07934.12 ABX13436.1 - 1.2e-09 38.3 1.9 0.00029 20.9 0.0 3.1 2 1 1 3 3 3 2 8-oxoguanine DNA glycosylase, N-terminal domain TraH PF06122.11 ABX13436.1 - 0.037 13.3 0.1 0.049 12.9 0.1 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein ILEI PF15711.5 ABX13436.1 - 0.079 13.5 0.4 0.31 11.5 0.3 2.0 1 1 0 1 1 1 0 Interleukin-like EMT inducer HHH PF00633.23 ABX13436.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4974 PF16344.5 ABX13436.1 - 0.14 12.1 7.3 1.6 8.8 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4974) DUF3579 PF12112.8 ABX13437.1 - 0.02 15.5 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) Copper-bind PF00127.20 ABX13438.1 - 7.6e-07 29.5 0.0 9.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family CbiM PF01891.16 ABX13438.1 - 0.028 14.2 0.6 0.036 13.9 0.6 1.1 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Cytochrome_B PF00033.19 ABX13439.1 - 4.1e-29 101.8 11.8 4.1e-29 101.8 11.8 2.8 3 1 0 3 3 3 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 ABX13439.1 - 1.2e-24 87.2 8.7 1.2e-24 87.2 8.7 3.1 3 1 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 ABX13439.1 - 2.2e-07 31.1 4.3 2.2e-07 31.1 4.3 3.3 5 0 0 5 5 5 1 Cytochrome b(C-terminal)/b6/petD DUF4405 PF14358.6 ABX13439.1 - 6.6e-05 23.4 3.5 6.6e-05 23.4 3.5 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF4405) S1FA PF04689.13 ABX13439.1 - 0.1 12.7 2.7 0.14 12.4 0.0 2.6 3 0 0 3 3 3 0 DNA binding protein S1FA DUF3899 PF13038.6 ABX13439.1 - 0.21 12.1 0.0 0.21 12.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) Tetraspanin PF00335.20 ABX13439.1 - 0.38 10.4 2.7 1.2 8.8 0.0 2.9 2 1 0 2 2 2 0 Tetraspanin family UPF0542 PF15086.6 ABX13439.1 - 0.73 9.8 2.8 0.5 10.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 OAD_gamma PF04277.13 ABX13439.1 - 1.6 9.4 0.0 1.6 9.4 0.0 4.2 3 1 1 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Rieske PF00355.26 ABX13440.1 - 7.2e-06 25.9 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain TAT_signal PF10518.9 ABX13440.1 - 3.2e-05 23.6 1.0 5.2e-05 22.9 1.0 1.3 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 ABX13440.1 - 0.0019 17.5 0.1 0.0043 16.4 0.1 1.6 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Peptidase_S8 PF00082.22 ABX13441.1 - 6.4e-33 114.3 0.0 1.6e-32 112.9 0.0 1.7 1 1 0 1 1 1 1 Subtilase family DUF916 PF06030.12 ABX13441.1 - 0.0054 16.8 0.5 0.37 10.9 0.0 3.7 4 0 0 4 4 4 1 Bacterial protein of unknown function (DUF916) fn3_5 PF06280.12 ABX13441.1 - 0.024 15.3 0.1 0.024 15.3 0.1 2.7 3 0 0 3 3 3 0 Fn3-like domain SpaA PF17802.1 ABX13442.1 - 0.02 15.2 1.1 0.08 13.3 0.1 2.3 2 0 0 2 2 2 0 Prealbumin-like fold domain Y_Y_Y PF07495.13 ABX13442.1 - 0.067 13.1 0.5 0.9 9.5 0.0 2.5 3 0 0 3 3 3 0 Y_Y_Y domain He_PIG PF05345.12 ABX13442.1 - 0.087 13.0 9.3 3.2 8.0 0.1 4.0 3 2 0 3 3 3 0 Putative Ig domain Flagellin_C PF00700.21 ABX13442.1 - 0.11 12.9 0.5 0.26 11.7 0.5 1.6 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region ThiF PF00899.21 ABX13444.1 - 1.3e-65 221.1 0.2 1.9e-65 220.6 0.2 1.1 1 0 0 1 1 1 1 ThiF family ThiS PF02597.20 ABX13444.1 - 6.8e-10 39.5 0.0 2.7e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 ThiS family Sacchrp_dh_NADP PF03435.18 ABX13444.1 - 5.2e-05 23.5 1.8 0.00019 21.7 1.8 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ABX13444.1 - 0.0019 18.2 0.2 0.0066 16.5 0.1 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ABX13444.1 - 0.0066 16.9 0.3 0.018 15.5 0.3 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.17 ABX13444.1 - 0.053 14.1 0.2 0.37 11.4 0.2 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ABX13444.1 - 0.096 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PALP PF00291.25 ABX13445.1 - 8.4e-68 228.9 0.2 9.8e-68 228.7 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACP_syn_III_C PF08541.10 ABX13445.1 - 0.094 12.9 0.6 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PRA-CH PF01502.18 ABX13447.1 - 6.2e-32 109.3 0.0 7.7e-32 109.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase His_biosynth PF00977.21 ABX13448.1 - 8.4e-84 280.6 1.5 9.7e-84 280.4 1.5 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 ABX13448.1 - 3.1e-08 33.1 0.0 0.00036 19.7 0.0 2.1 1 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 ABX13448.1 - 3.8e-07 29.8 0.1 0.0056 16.1 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase TMP-TENI PF02581.17 ABX13448.1 - 9.4e-05 21.8 0.3 0.23 10.7 0.0 2.3 2 0 0 2 2 2 2 Thiamine monophosphate synthase ThiG PF05690.14 ABX13448.1 - 0.0012 18.2 2.2 0.65 9.3 0.1 2.5 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 ABX13448.1 - 0.0047 16.2 0.0 0.035 13.3 0.0 2.0 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Trp_syntA PF00290.20 ABX13448.1 - 0.0079 15.1 0.1 0.013 14.4 0.1 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain G3P_antiterm PF04309.12 ABX13448.1 - 0.016 14.7 0.2 1.2 8.5 0.1 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 ABX13448.1 - 0.037 13.5 0.9 0.12 11.8 0.1 2.1 2 1 1 3 3 3 0 PcrB family TRI9 PF08195.11 ABX13448.1 - 0.081 12.8 0.0 15 5.6 0.0 2.4 2 0 0 2 2 2 0 TRI9 protein IMPDH PF00478.25 ABX13448.1 - 0.19 10.7 3.5 0.67 8.9 0.6 2.1 1 1 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 ABX13449.1 - 2e-71 240.1 1.1 2.3e-71 239.9 1.1 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.17 ABX13449.1 - 1.7e-06 27.7 0.9 0.028 13.9 0.1 2.1 2 0 0 2 2 2 2 PcrB family IGPS PF00218.21 ABX13449.1 - 4.7e-06 25.9 0.4 0.042 13.0 0.0 2.1 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase PRAI PF00697.22 ABX13449.1 - 0.0089 15.8 0.6 0.016 15.0 0.0 1.6 2 1 0 2 2 2 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase ThiG PF05690.14 ABX13449.1 - 0.01 15.2 0.1 0.53 9.5 0.0 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.15 ABX13449.1 - 0.01 15.2 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase Trp_syntA PF00290.20 ABX13449.1 - 0.012 14.5 0.3 0.68 8.7 0.0 2.5 3 0 0 3 3 3 0 Tryptophan synthase alpha chain G3P_antiterm PF04309.12 ABX13449.1 - 0.02 14.3 0.5 2.6 7.4 0.0 2.6 2 1 1 3 3 3 0 Glycerol-3-phosphate responsive antiterminator TMP-TENI PF02581.17 ABX13449.1 - 0.047 13.0 0.0 11 5.3 0.0 2.5 2 1 0 2 2 2 0 Thiamine monophosphate synthase Dus PF01207.17 ABX13449.1 - 0.061 12.4 0.1 8.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) IMPDH PF00478.25 ABX13449.1 - 0.11 11.5 0.3 4 6.4 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain GATase PF00117.28 ABX13450.1 - 8.1e-23 81.2 0.0 9.5e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 ABX13450.1 - 0.00015 21.7 0.0 0.0011 18.9 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 ABX13450.1 - 0.0002 21.2 1.0 0.02 14.7 1.0 2.8 1 1 0 1 1 1 1 Peptidase C26 IGPD PF00475.18 ABX13451.1 - 1.7e-46 158.1 1.1 2.2e-46 157.8 1.1 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF916 PF06030.12 ABX13451.1 - 0.025 14.7 0.1 0.069 13.2 0.0 1.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF916) Hydrolase PF00702.26 ABX13452.1 - 6.3e-11 43.0 0.0 3.6e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ABX13452.1 - 1.5e-10 41.5 3.9 9.4e-08 32.3 3.9 3.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ABX13452.1 - 0.0015 18.6 0.0 0.0042 17.1 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 ABX13452.1 - 0.048 13.8 0.1 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 ABX13452.1 - 0.064 13.7 0.0 1.3 9.4 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.21 ABX13453.1 - 4e-50 171.0 0.0 4.5e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 ABX13453.1 - 5.3e-07 28.8 0.0 7e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Allinase Aminotran_5 PF00266.19 ABX13453.1 - 0.015 14.3 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V HTH_22 PF13309.6 ABX13453.1 - 0.11 12.5 0.4 5.1 7.3 0.1 2.7 2 0 0 2 2 2 0 HTH domain Histidinol_dh PF00815.20 ABX13454.1 - 5.8e-135 450.4 0.5 6.6e-135 450.2 0.5 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase HTH_Tnp_IS630 PF01710.16 ABX13454.1 - 1 9.4 7.5 0.29 11.2 3.9 2.0 2 1 0 2 2 2 0 Transposase RFX5_N PF18326.1 ABX13454.1 - 1.3 8.9 7.4 2.1 8.2 0.6 2.7 2 0 0 2 2 2 0 RFX5 N-terminal domain HisG PF01634.18 ABX13455.1 - 8.5e-43 146.1 0.0 1.1e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 ABX13455.1 - 7.8e-15 54.8 0.0 2e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain HMG-CoA_red PF00368.18 ABX13456.1 - 8.2e-108 360.7 4.9 1e-107 360.4 4.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase PCI PF01399.27 ABX13456.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 PCI domain DUF4342 PF14242.6 ABX13456.1 - 0.15 12.1 1.7 1.3 9.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) SseC PF04888.12 ABX13456.1 - 0.2 11.2 13.0 0.22 11.1 0.2 3.2 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family GSDH PF07995.11 ABX13457.1 - 1e-85 288.0 0.0 1.4e-85 287.5 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 ABX13457.1 - 0.00016 21.5 0.5 8.9 6.9 0.0 4.1 3 0 0 3 3 3 1 Two component regulator propeller NHL PF01436.21 ABX13457.1 - 0.00095 19.1 0.0 4 7.7 0.0 3.5 3 0 0 3 3 3 2 NHL repeat PQQ_3 PF13570.6 ABX13457.1 - 0.0093 16.4 0.1 26 5.5 0.0 4.3 5 0 0 5 5 5 1 PQQ-like domain SGL PF08450.12 ABX13457.1 - 0.082 12.5 0.0 9 5.8 0.0 2.6 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region DUF5122 PF17164.4 ABX13457.1 - 0.29 11.5 3.8 1.4 9.3 0.3 3.8 5 1 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller DUF1743 PF08489.11 ABX13458.1 - 4e-37 126.8 0.0 2.3e-36 124.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1743) OrfB_Zn_ribbon PF07282.11 ABX13458.1 - 0.009 15.9 0.6 0.02 14.8 0.6 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain C1_1 PF00130.22 ABX13458.1 - 0.79 9.7 4.0 1.5 8.7 4.0 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Diphthamide_syn PF01866.17 ABX13459.1 - 6.8e-65 219.5 0.0 8e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPR_1 PF00515.28 ABX13460.1 - 3.5e-19 67.7 1.8 1.9e-07 30.6 0.8 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 ABX13460.1 - 2e-17 61.8 0.1 8.1e-06 25.6 0.3 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 ABX13460.1 - 1.9e-12 47.5 0.0 1.7e-07 31.6 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ABX13460.1 - 8.7e-12 44.3 5.6 1e-05 25.4 0.8 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ABX13460.1 - 1.8e-10 41.3 0.0 1.6e-08 35.1 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ABX13460.1 - 9e-10 38.6 0.0 0.094 13.4 0.2 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 ABX13460.1 - 1.5e-08 34.8 0.0 6.4e-05 23.2 0.3 3.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 ABX13460.1 - 2.7e-08 33.9 0.0 0.16 12.9 0.0 4.4 3 1 2 5 5 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ABX13460.1 - 5e-08 32.9 0.6 0.14 12.2 0.1 4.3 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 ABX13460.1 - 1.4e-06 27.9 0.6 0.16 12.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ABX13460.1 - 2e-06 27.8 6.4 0.0012 19.1 0.4 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ABX13460.1 - 2.7e-06 27.5 2.6 0.0014 18.8 0.8 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 ABX13460.1 - 6.6e-06 25.8 0.0 0.02 14.7 0.1 3.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 ABX13460.1 - 2.4e-05 23.9 2.5 0.001 18.7 0.7 3.1 3 1 1 4 4 4 1 TPR repeat TPR_9 PF13371.6 ABX13460.1 - 0.0012 18.9 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 ABX13460.1 - 0.0026 17.8 2.5 1.3 9.1 0.4 2.3 2 0 0 2 2 2 2 Putative TPR-like repeat DUF4919 PF16266.5 ABX13460.1 - 0.0059 16.6 0.1 0.018 15.0 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4919) TPR_3 PF07720.12 ABX13460.1 - 0.0064 16.5 2.1 0.15 12.1 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR PF01535.20 ABX13460.1 - 0.0069 16.6 0.6 8 7.0 0.0 3.7 4 0 0 4 4 4 1 PPR repeat ATP13 PF12921.7 ABX13460.1 - 0.052 13.4 0.1 0.68 9.8 0.1 2.6 1 1 2 3 3 3 0 Mitochondrial ATPase expression MIT PF04212.18 ABX13460.1 - 1.3 9.1 4.4 9.8 6.3 0.3 2.6 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain ADH_N PF08240.12 ABX13461.1 - 2.5e-25 88.5 0.3 4e-25 87.8 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABX13461.1 - 1.7e-24 86.2 0.0 2.8e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABX13461.1 - 6.1e-18 66.2 0.0 9.8e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.10 ABX13461.1 - 0.15 12.2 0.3 0.52 10.5 0.2 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal C1_2 PF03107.16 ABX13461.1 - 0.22 11.8 1.8 0.43 10.9 1.8 1.3 1 0 0 1 1 1 0 C1 domain ECR1_N PF14382.6 ABX13462.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 ABX13462.1 - 0.033 14.8 0.6 0.23 12.1 0.2 2.1 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 DNA_RNApol_7kD PF03604.13 ABX13462.1 - 2.1 8.1 7.4 29 4.5 7.4 2.4 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit PDT PF00800.18 ABX13463.1 - 4.3e-59 199.4 0.4 5.6e-59 199.0 0.4 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 ABX13463.1 - 0.00012 21.8 0.0 0.0003 20.5 0.0 1.7 2 0 0 2 2 2 1 ACT domain IMPDH PF00478.25 ABX13465.1 - 3.6e-147 489.9 9.5 4.1e-147 489.7 9.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 ABX13465.1 - 4.9e-25 87.7 1.5 8.2e-11 42.2 0.0 3.4 4 0 0 4 4 4 2 CBS domain NMO PF03060.15 ABX13465.1 - 2e-10 40.6 6.8 6.5e-06 25.8 3.9 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 ABX13465.1 - 1.4e-06 27.9 1.5 0.019 14.4 0.1 2.5 1 1 0 2 2 2 2 Histidine biosynthesis protein FMN_dh PF01070.18 ABX13465.1 - 4.2e-06 26.0 10.3 1.9e-05 23.8 10.3 2.2 1 1 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 ABX13465.1 - 0.00022 20.6 6.4 0.00068 18.9 1.2 2.5 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase NanE PF04131.14 ABX13465.1 - 0.0021 17.3 2.0 0.0021 17.3 2.0 2.2 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 ABX13465.1 - 0.047 13.0 2.1 0.078 12.3 0.7 2.1 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG Pterin_bind PF00809.22 ABX13466.1 - 2.2e-48 165.1 0.0 3.9e-48 164.3 0.0 1.4 1 1 0 1 1 1 1 Pterin binding enzyme MAF_flag10 PF01973.18 ABX13467.1 - 1e-41 142.5 0.4 1.7e-41 141.8 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF115 S6PP_C PF08472.10 ABX13467.1 - 0.03 14.2 0.4 0.36 10.7 0.0 2.4 2 1 1 3 3 3 0 Sucrose-6-phosphate phosphohydrolase C-terminal DUF4094 PF13334.6 ABX13468.1 - 0.13 12.7 0.5 0.13 12.7 0.5 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) GATase PF00117.28 ABX13469.1 - 5.6e-42 143.7 0.0 7.9e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 ABX13469.1 - 4.5e-34 116.4 0.0 9.5e-34 115.3 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 ABX13469.1 - 2.8e-10 39.7 0.2 1.3e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 ABX13469.1 - 8.6e-08 32.2 0.1 3.7e-07 30.1 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 ThiI PF02568.14 ABX13469.1 - 0.0001 22.0 0.0 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 ABX13469.1 - 0.00075 18.4 0.0 0.0046 15.8 0.0 2.0 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 ABX13469.1 - 0.031 13.8 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC DUF2024 PF09630.10 ABX13471.1 - 2.7e-35 120.1 2.2 2.9e-35 120.0 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) Ribonuc_red_sm PF00268.21 ABX13471.1 - 0.061 12.8 0.1 0.063 12.7 0.1 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain ROK PF00480.20 ABX13472.1 - 5.4e-71 239.5 0.0 6.1e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 ABX13472.1 - 7.2e-05 22.4 0.1 0.00073 19.1 0.1 2.2 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Glucokinase PF02685.16 ABX13472.1 - 0.035 13.1 1.2 0.1 11.6 1.2 1.7 1 1 0 1 1 1 0 Glucokinase Hydant_A_N PF05378.13 ABX13472.1 - 0.036 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Cpn60_TCP1 PF00118.24 ABX13473.1 - 3.3e-180 599.9 19.8 3.9e-180 599.7 19.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Adenine_deam_C PF13382.6 ABX13474.1 - 1.2e-45 154.9 0.0 1.8e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 ABX13474.1 - 4.3e-17 62.5 0.0 4.8e-16 59.0 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABX13474.1 - 6.4e-09 35.8 0.0 0.00041 19.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Ribosomal_L44 PF00935.19 ABX13475.1 - 3.7e-24 85.0 9.0 3.7e-24 85.0 9.0 1.6 1 1 1 2 2 2 1 Ribosomal protein L44 Ribosomal_L33 PF00471.20 ABX13475.1 - 0.0074 16.7 5.2 0.22 12.0 1.7 2.6 2 0 0 2 2 2 2 Ribosomal protein L33 Ribosomal_S27e PF01667.17 ABX13476.1 - 4e-17 61.7 1.0 4.8e-17 61.4 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 zf-ribbon_3 PF13248.6 ABX13476.1 - 0.00094 18.5 1.6 0.8 9.2 0.2 2.2 2 0 0 2 2 2 2 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 ABX13476.1 - 0.00094 19.2 0.8 0.0011 19.0 0.8 1.1 1 0 0 1 1 1 1 Transposase zinc-binding domain TF_Zn_Ribbon PF08271.12 ABX13476.1 - 0.0054 16.2 0.3 0.0068 15.9 0.3 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding zf-dskA_traR PF01258.17 ABX13476.1 - 0.0081 16.1 0.3 2.4 8.1 0.0 2.2 2 0 0 2 2 2 2 Prokaryotic dksA/traR C4-type zinc finger zinc_ribbon_6 PF14599.6 ABX13476.1 - 0.0082 16.1 2.2 0.02 14.9 2.3 1.6 1 1 0 1 1 1 1 Zinc-ribbon ZZ PF00569.17 ABX13476.1 - 0.016 15.0 4.8 1.1 9.1 0.4 2.2 1 1 1 2 2 2 0 Zinc finger, ZZ type YhfH PF14149.6 ABX13476.1 - 0.021 14.8 1.1 2.1 8.4 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein HypA PF01155.19 ABX13476.1 - 0.028 14.4 0.8 0.033 14.2 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ACC PF17848.1 ABX13476.1 - 0.035 14.2 1.4 6.6 6.9 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Zn-ribbon_8 PF09723.10 ABX13476.1 - 0.055 13.6 1.1 0.1 12.7 1.1 1.5 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_7 PF15269.6 ABX13476.1 - 0.079 13.0 0.1 0.092 12.8 0.1 1.1 1 0 0 1 1 1 0 Zinc-finger HalOD2 PF18547.1 ABX13476.1 - 0.11 12.4 2.8 2.6 8.0 0.5 2.2 1 1 1 2 2 2 0 Halobacterial output domain 2 zf-BED PF02892.15 ABX13476.1 - 0.12 12.5 3.7 3.5 7.7 0.3 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_3 PF13878.6 ABX13476.1 - 5.4 6.9 6.9 3.6 7.5 1.3 2.2 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO NTP_transf_3 PF12804.7 ABX13477.1 - 1.3e-14 54.9 0.0 1.6e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 ABX13477.1 - 3.8e-08 33.3 0.0 5.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transferase PF00483.23 ABX13477.1 - 0.00016 21.4 0.0 0.0003 20.5 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase CTP_transf_3 PF02348.19 ABX13477.1 - 0.015 15.2 0.3 0.033 14.1 0.3 1.7 1 1 0 1 1 1 0 Cytidylyltransferase RMMBL PF07521.12 ABX13477.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain CobS PF02654.15 ABX13478.1 - 2.8e-41 142.0 18.2 3.2e-41 141.8 18.2 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase CobD_Cbib PF03186.13 ABX13479.1 - 7.3e-89 297.6 0.2 9.2e-89 297.3 0.2 1.2 1 0 0 1 1 1 1 CobD/Cbib protein DUF4199 PF13858.6 ABX13479.1 - 0.0086 16.5 7.9 0.34 11.3 0.0 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF4199) CbiA PF01656.23 ABX13480.1 - 1.4e-18 67.2 0.0 3.8e-18 65.8 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 ABX13480.1 - 6.3e-18 65.3 0.1 8.3e-17 61.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 ABX13480.1 - 0.003 17.4 0.1 0.14 12.1 0.0 2.7 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B CBP_BcsQ PF06564.12 ABX13480.1 - 0.011 15.2 0.0 0.37 10.2 0.0 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ ABC_tran PF00005.27 ABX13480.1 - 0.018 15.5 0.0 0.078 13.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter SelA PF03841.13 ABX13480.1 - 0.024 13.6 0.2 0.028 13.4 0.2 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase SRP54 PF00448.22 ABX13480.1 - 0.031 13.9 0.2 7 6.2 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 ABX13480.1 - 0.045 14.1 0.0 0.074 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 ABX13480.1 - 0.15 11.8 0.0 0.6 9.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.21 ABX13481.1 - 1.4e-50 172.5 0.0 1.6e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 ABX13481.1 - 1.8e-06 27.1 0.1 0.00091 18.2 0.0 2.3 2 0 0 2 2 2 2 Allinase Semialdhyde_dhC PF02774.18 ABX13482.1 - 1.9e-31 109.6 0.0 3.1e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ABX13482.1 - 2.4e-28 99.0 0.0 4.6e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ABX13482.1 - 0.029 14.5 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 ABX13482.1 - 0.051 14.3 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GFO_IDH_MocA PF01408.22 ABX13482.1 - 0.053 14.3 0.0 0.099 13.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold AsnC_trans_reg PF01037.21 ABX13483.1 - 4e-12 45.9 0.1 5.5e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain SAM_LFY PF01698.16 ABX13483.1 - 0.07 13.1 0.6 4.8 7.2 0.0 2.2 1 1 1 2 2 2 0 Floricaula / Leafy protein SAM domain B-block_TFIIIC PF04182.12 ABX13483.1 - 0.11 12.6 0.1 0.25 11.5 0.1 1.6 2 1 0 2 2 2 0 B-block binding subunit of TFIIIC UbiA PF01040.18 ABX13484.1 - 6e-37 127.3 23.1 7.9e-37 126.9 23.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family ApoLp-III PF07464.11 ABX13486.1 - 0.01 16.0 7.5 0.022 14.9 6.9 1.8 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) HEPN_Toprim_N PF18871.1 ABX13486.1 - 0.034 14.1 3.5 0.048 13.6 2.0 1.8 1 1 1 2 2 2 0 HEPN/Toprim N-terminal domain 1 CCDC106 PF15794.5 ABX13486.1 - 0.12 12.0 0.2 0.12 12.0 0.2 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 UPF0061 PF02696.14 ABX13486.1 - 0.16 10.7 4.6 0.2 10.4 4.6 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family TPR_11 PF13414.6 ABX13486.1 - 0.28 10.9 2.5 33 4.3 0.0 3.2 2 1 1 3 3 3 0 TPR repeat DUF3080 PF11279.8 ABX13486.1 - 0.44 9.7 8.9 0.086 12.1 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3080) RPAP3_C PF13877.6 ABX13486.1 - 0.54 10.8 5.6 13 6.4 5.6 2.9 1 1 0 1 1 1 0 Potential Monad-binding region of RPAP3 DUF5344 PF17279.2 ABX13486.1 - 1.7 9.3 6.8 1.1 9.9 1.3 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5344) CTK3_C PF12350.8 ABX13486.1 - 2.4 8.4 9.8 9.9 6.4 0.8 2.9 1 1 1 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus TCTP PF00838.17 ABX13486.1 - 3.1 8.1 8.3 0.55 10.6 1.3 2.2 1 1 0 2 2 2 0 Translationally controlled tumour protein DUF2680 PF10925.8 ABX13487.1 - 8.9e-07 28.8 46.5 0.76 9.8 0.3 9.9 11 1 1 12 12 12 6 Protein of unknown function (DUF2680) HSBP1 PF06825.12 ABX13487.1 - 4e-06 26.6 28.8 0.74 9.7 0.0 8.9 8 1 1 9 9 9 5 Heat shock factor binding protein 1 DUF3892 PF13031.6 ABX13487.1 - 0.00086 19.9 1.3 0.0015 19.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3892) DUF465 PF04325.13 ABX13487.1 - 0.0078 16.2 48.9 0.79 9.8 1.3 8.8 5 2 3 8 8 8 3 Protein of unknown function (DUF465) DASH_Dad1 PF08649.10 ABX13487.1 - 0.1 12.8 1.2 0.49 10.6 1.2 2.3 1 0 0 1 1 1 0 DASH complex subunit Dad1 HypA PF01155.19 ABX13487.1 - 0.11 12.5 3.4 0.22 11.6 3.4 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Noelin-1 PF12308.8 ABX13487.1 - 0.69 9.9 12.1 4.5 7.3 0.1 4.7 4 2 2 6 6 6 0 Neurogenesis glycoprotein CorA PF01544.18 ABX13487.1 - 2 7.6 31.1 2 7.6 1.2 5.1 4 2 1 5 5 5 0 CorA-like Mg2+ transporter protein FlxA PF14282.6 ABX13487.1 - 6.1 6.9 67.3 0.22 11.5 9.8 5.3 4 1 1 5 5 5 0 FlxA-like protein APG6_N PF17675.1 ABX13489.1 - 0.82 10.2 6.1 1.1 9.7 4.8 1.9 2 1 0 2 2 2 0 Apg6 coiled-coil region DDE_Tnp_ISL3 PF01610.17 ABX13491.1 - 0.00022 21.0 6.5 0.048 13.4 0.3 2.1 1 1 1 2 2 2 2 Transposase CDC37_C PF08564.10 ABX13491.1 - 0.0019 18.3 1.5 6.3 7.0 0.1 3.0 1 1 2 3 3 3 1 Cdc37 C terminal domain YkyA PF10368.9 ABX13491.1 - 0.0022 17.7 4.4 0.098 12.3 0.1 2.5 1 1 1 2 2 2 2 Putative cell-wall binding lipoprotein Spore_III_AB PF09548.10 ABX13491.1 - 0.0045 17.1 3.6 0.0057 16.8 3.6 1.1 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) SnoaL PF07366.12 ABX13491.1 - 0.0056 16.5 0.2 0.011 15.6 0.2 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF5486 PF17588.2 ABX13491.1 - 0.015 15.2 0.7 3.3 7.7 0.0 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5486) Phasin PF05597.11 ABX13491.1 - 0.03 14.3 0.5 0.061 13.3 0.2 1.6 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HNOB PF07700.15 ABX13491.1 - 0.03 14.3 2.3 0.038 13.9 1.8 1.4 1 1 0 1 1 1 0 Haem-NO-binding HBM PF16591.5 ABX13491.1 - 0.04 13.3 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Helical bimodular sensor domain Mating_N PF12731.7 ABX13491.1 - 0.049 13.7 4.9 0.13 12.4 0.9 3.0 1 1 1 2 2 2 0 Mating-type protein beta 1 ERp29 PF07749.12 ABX13491.1 - 0.085 13.8 1.2 12 6.9 0.1 2.3 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF3654 PF12376.8 ABX13491.1 - 0.24 11.6 1.8 0.27 11.4 1.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3654) DASH_Dad2 PF08654.10 ABX13491.1 - 0.27 11.7 6.9 0.25 11.8 0.8 2.6 1 1 1 2 2 2 0 DASH complex subunit Dad2 ECH_1 PF00378.20 ABX13491.1 - 0.27 10.5 4.0 0.41 9.9 1.4 1.9 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase DUF4446 PF14584.6 ABX13491.1 - 0.35 10.8 3.5 7.8 6.5 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) TipAS PF07739.13 ABX13491.1 - 0.69 10.5 9.7 1e+02 3.5 9.7 2.2 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain MbeD_MobD PF04899.12 ABX13491.1 - 2.7 8.2 11.8 0.053 13.7 2.8 2.6 2 1 0 2 2 2 0 MbeD/MobD like FAA_hydro_N_2 PF18288.1 ABX13491.1 - 3.1 8.3 6.4 2.6 8.6 0.8 2.8 1 1 2 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 DUF4298 PF14131.6 ABX13491.1 - 3.7 7.6 10.4 4.8 7.2 1.9 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4298) HMG_box_2 PF09011.10 ABX13491.1 - 9.7 6.9 16.4 0.37 11.4 1.9 3.2 1 1 2 3 3 3 0 HMG-box domain 4HBT PF03061.22 ABX13492.1 - 4.2e-14 52.7 0.1 6.2e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 ABX13492.1 - 0.00017 21.1 0.2 0.00041 19.9 0.1 1.6 1 1 1 2 2 2 1 MaoC like domain RlmM_FDX PF18125.1 ABX13492.1 - 0.1 13.1 0.0 0.55 10.7 0.0 1.9 1 1 1 2 2 2 0 RlmM ferredoxin-like domain UbiD PF01977.16 ABX13493.1 - 6.9e-95 318.3 0.1 7.8e-95 318.1 0.1 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase PAC4 PF16093.5 ABX13494.1 - 2.6e-05 24.3 0.1 3.4e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 DUF1108 PF06531.11 ABX13494.1 - 0.029 14.7 0.2 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1108) RPA_interact_C PF14768.6 ABX13495.1 - 0.12 13.0 5.7 4.9 7.8 5.7 2.7 1 1 0 1 1 1 0 Replication protein A interacting C-terminal FdhD-NarQ PF02634.15 ABX13495.1 - 0.28 10.8 2.6 0.36 10.5 2.6 1.1 1 0 0 1 1 1 0 FdhD/NarQ family Jas PF16135.5 ABX13495.1 - 0.3 11.3 7.1 3.4 7.9 2.2 2.3 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling C1_1 PF00130.22 ABX13495.1 - 0.31 11.0 12.0 0.48 10.3 1.6 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YyzF PF14116.6 ABX13495.1 - 3.4 7.8 6.9 14 5.8 4.5 2.8 2 1 0 2 2 2 0 YyzF-like protein zinc_ribbon_15 PF17032.5 ABX13495.1 - 5.8 7.7 14.0 8.4 7.2 4.0 2.3 2 0 0 2 2 2 0 zinc-ribbon family DUF460 PF04312.13 ABX13496.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) COG6 PF06419.11 ABX13497.1 - 0.0012 17.1 3.5 0.0016 16.8 3.5 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Apolipoprotein PF01442.18 ABX13497.1 - 0.01 15.7 6.7 0.016 15.1 6.7 1.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3723 PF12520.8 ABX13497.1 - 0.011 14.4 0.1 0.014 14.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) V-ATPase_G PF03179.15 ABX13497.1 - 0.013 16.0 7.1 0.017 15.6 7.1 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Hemagglutinin PF00509.18 ABX13497.1 - 0.03 12.7 1.4 0.033 12.6 1.4 1.1 1 0 0 1 1 1 0 Haemagglutinin CsoSCA PF08936.10 ABX13497.1 - 0.031 13.0 1.6 0.036 12.7 1.6 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase DUF4972 PF16342.5 ABX13497.1 - 0.052 13.2 0.8 0.052 13.2 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) Muted PF14942.6 ABX13497.1 - 0.062 13.6 6.7 0.86 9.9 6.1 1.7 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein V-ATPase_G_2 PF16999.5 ABX13497.1 - 0.1 13.0 10.9 0.96 9.9 10.9 2.2 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit YabA PF06156.13 ABX13497.1 - 0.11 13.1 2.6 0.16 12.6 2.6 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF2015 PF09435.10 ABX13497.1 - 0.12 12.3 2.3 0.59 10.0 1.1 2.0 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF2015) SlyX PF04102.12 ABX13497.1 - 0.12 13.0 1.3 0.21 12.2 0.9 1.8 1 1 0 1 1 1 0 SlyX Phage_Mu_Gam PF07352.12 ABX13497.1 - 0.13 12.2 8.2 1.2 9.1 0.2 2.0 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF883 PF05957.13 ABX13497.1 - 0.17 12.5 6.3 2 9.1 2.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Spc24 PF08286.11 ABX13497.1 - 0.28 11.5 6.6 2.3 8.5 6.6 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIVA PF05103.13 ABX13497.1 - 0.44 10.6 10.8 0.7 10.0 10.8 1.3 1 1 0 1 1 1 0 DivIVA protein NPV_P10 PF05531.12 ABX13497.1 - 1 9.8 5.8 7.7 7.1 5.8 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein YtxH PF12732.7 ABX13497.1 - 6.3 7.4 11.3 3 8.5 1.7 2.1 1 1 1 2 2 2 0 YtxH-like protein NAC PF01849.18 ABX13498.1 - 5.3e-15 55.1 1.6 7.7e-15 54.6 0.8 1.6 2 0 0 2 2 2 1 NAC domain UBA_4 PF14555.6 ABX13498.1 - 0.012 15.4 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 UBA-like domain PUA PF01472.20 ABX13499.1 - 6.1e-09 35.7 0.2 1.2e-08 34.8 0.2 1.5 1 0 0 1 1 1 1 PUA domain TGT_C2 PF14810.6 ABX13499.1 - 2.7e-08 33.8 0.0 4.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Patch-forming domain C2 of tRNA-guanine transglycosylase PhoU PF01895.19 ABX13500.1 - 1.3e-25 89.7 12.1 2.8e-17 62.9 0.6 2.5 2 0 0 2 2 2 2 PhoU domain MazE_antitoxin PF04014.18 ABX13500.1 - 2.2e-07 30.6 0.0 7.3e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin KMP11 PF03037.16 ABX13500.1 - 0.014 16.2 1.7 0.039 14.7 1.7 1.8 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 UBA PF00627.31 ABX13500.1 - 0.18 11.8 0.8 13 5.8 0.1 3.3 3 0 0 3 3 3 0 UBA/TS-N domain GTP-bdg_N PF13167.6 ABX13501.1 - 1.4e-18 67.4 0.1 3.1e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 ABX13501.1 - 1.9e-16 60.4 2.0 4.4e-16 59.2 2.0 1.6 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 ABX13501.1 - 2.4e-16 59.8 0.1 6.9e-16 58.4 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ABX13501.1 - 9.9e-10 38.2 0.2 1.7e-09 37.4 0.2 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ABX13501.1 - 5.7e-07 29.6 2.0 0.01 15.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ABX13501.1 - 1.3e-05 24.8 0.8 0.00051 19.6 0.8 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 ABX13501.1 - 0.00025 20.5 0.6 0.00065 19.2 0.6 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 ABX13501.1 - 0.00032 20.7 0.3 0.00086 19.3 0.3 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 ABX13501.1 - 0.002 18.6 0.1 0.0059 17.1 0.0 2.0 2 1 0 2 2 2 1 ABC transporter MnmE_helical PF12631.7 ABX13501.1 - 0.0064 16.7 0.7 0.01 16.0 0.1 1.5 2 0 0 2 2 2 1 MnmE helical domain Ras PF00071.22 ABX13501.1 - 0.0078 15.8 0.6 0.034 13.8 0.6 2.0 1 1 0 1 1 1 1 Ras family Trans_reg_C PF00486.28 ABX13501.1 - 0.025 14.6 0.3 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal cobW PF02492.19 ABX13501.1 - 0.031 13.8 1.1 4.6 6.8 0.1 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 ABX13501.1 - 0.092 13.0 0.2 0.97 9.7 0.1 2.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 ABX13501.1 - 0.32 10.7 4.6 4.7 7.0 2.5 3.3 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Trm56 PF01994.16 ABX13502.1 - 2.7e-49 166.0 0.1 3.6e-49 165.6 0.1 1.2 1 0 0 1 1 1 1 tRNA ribose 2'-O-methyltransferase, aTrm56 SpoU_methylase PF00588.19 ABX13502.1 - 4.7e-05 23.6 0.0 6.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SPOUT_MTase_2 PF14419.6 ABX13502.1 - 0.019 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP TFIIE_alpha PF02002.17 ABX13503.1 - 1.1e-15 57.3 1.3 1.1e-15 57.3 1.3 1.5 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 ABX13503.1 - 0.01 15.3 0.6 0.022 14.3 0.6 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding TrmB PF01978.19 ABX13503.1 - 0.069 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sigma70_r3 PF04539.16 ABX13503.1 - 0.071 13.2 0.7 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 DUF3834 PF12916.7 ABX13503.1 - 0.086 12.1 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) zf-ACC PF17848.1 ABX13503.1 - 0.088 12.9 0.2 0.25 11.4 0.2 1.8 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain IBR PF01485.21 ABX13503.1 - 0.099 12.9 0.9 0.16 12.2 0.9 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 ABX13503.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zf_CopZ PF18423.1 ABX13503.1 - 0.2 11.6 0.3 0.2 11.6 0.3 2.3 1 1 1 2 2 2 0 Zinc binding domain Zn_ribbon_recom PF13408.6 ABX13503.1 - 0.23 12.0 0.1 0.23 12.0 0.1 2.2 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain ORF11CD3 PF10549.9 ABX13503.1 - 0.96 9.6 4.6 7.2 6.8 0.1 3.1 4 0 0 4 4 4 0 ORF11CD3 domain Aldedh PF00171.22 ABX13504.1 - 1e-141 472.6 0.0 1.1e-141 472.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ABX13504.1 - 0.00026 20.2 0.0 0.00039 19.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) SNAD3 PF18749.1 ABX13504.1 - 0.0024 17.1 0.3 0.0041 16.3 0.3 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 3 CdiI_2 PF18593.1 ABX13505.1 - 0.073 13.7 0.8 0.27 11.9 0.0 1.9 1 1 1 2 2 2 0 CdiI immunity protein Hemerythrin PF01814.23 ABX13506.1 - 1e-12 48.8 3.2 1.1e-12 48.8 0.6 2.2 2 1 0 2 2 2 1 Hemerythrin HHE cation binding domain Prominin PF05478.11 ABX13506.1 - 0.00093 17.3 0.1 0.0013 16.8 0.1 1.2 1 0 0 1 1 1 1 Prominin DUF1043 PF06295.12 ABX13506.1 - 0.06 13.4 2.3 0.15 12.1 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) IZUMO PF15005.6 ABX13506.1 - 0.12 12.9 1.1 0.19 12.2 0.3 1.7 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated SWIB PF02201.18 ABX13507.1 - 0.0043 16.9 0.0 0.0077 16.1 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Peptidase_S49_N PF08496.10 ABX13507.1 - 7.9 6.5 7.3 9.7 6.2 7.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RibD_C PF01872.17 ABX13508.1 - 3.3e-48 164.2 0.1 3.7e-48 164.0 0.1 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Tex_YqgF PF16921.5 ABX13508.1 - 0.0077 16.7 0.6 1.7 9.1 0.0 2.2 1 1 1 2 2 2 2 Tex protein YqgF-like domain Mito_fiss_Elm1 PF06258.11 ABX13508.1 - 0.078 12.1 0.0 0.19 10.9 0.0 1.4 1 1 0 1 1 1 0 Mitochondrial fission ELM1 QRPTase_C PF01729.19 ABX13508.1 - 0.11 12.2 0.3 0.45 10.3 0.1 2.0 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Amidohydro_1 PF01979.20 ABX13509.1 - 8.5e-39 133.8 0.9 1.2e-38 133.4 0.9 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABX13509.1 - 5e-11 42.7 0.0 6.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family GCH_III PF05165.12 ABX13510.1 - 3.3e-48 164.1 0.0 4.2e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase III mCpol PF18182.1 ABX13510.1 - 1.3e-05 25.5 0.8 0.11 12.8 0.1 2.2 2 0 0 2 2 2 2 minimal CRISPR polymerase domain Guanylate_cyc PF00211.20 ABX13510.1 - 0.0066 16.1 0.4 0.012 15.2 0.1 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain F420H2_quin_red PF04075.14 ABX13510.1 - 0.017 15.2 0.0 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 F420H(2)-dependent quinone reductase YpsA PF06908.11 ABX13510.1 - 0.063 13.3 0.1 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 YspA SLOG family Ribosomal_L5 PF00281.19 ABX13510.1 - 0.077 13.3 0.1 0.61 10.5 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L5 NOG1 PF06858.14 ABX13510.1 - 0.084 12.7 0.5 0.29 11.0 0.1 2.1 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) GGDEF PF00990.21 ABX13510.1 - 0.1 12.3 0.1 8.9 6.0 0.0 2.7 2 2 0 2 2 2 0 Diguanylate cyclase, GGDEF domain DMRL_synthase PF00885.19 ABX13511.1 - 3.1e-32 111.3 0.8 3.6e-32 111.1 0.8 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase MapZ_EC1 PF18041.1 ABX13511.1 - 0.001 19.3 0.1 0.0014 18.8 0.1 1.2 1 0 0 1 1 1 1 MapZ extracellular domain 1 Phage_TAC_11 PF11836.8 ABX13511.1 - 0.11 12.7 0.2 1.7 8.8 0.0 2.0 1 1 0 2 2 2 0 Phage tail tube protein, GTA-gp10 DHBP_synthase PF00926.19 ABX13512.1 - 5.8e-61 205.4 0.0 6.7e-61 205.2 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PAF-AH_p_II PF03403.13 ABX13512.1 - 0.077 11.5 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Lum_binding PF00677.17 ABX13513.1 - 2.8e-45 152.2 7.8 7.2e-26 90.0 0.3 2.0 2 0 0 2 2 2 2 Lumazine binding domain TPR_1 PF00515.28 ABX13514.1 - 6.9e-26 89.0 7.9 1.9e-08 33.8 0.1 5.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 ABX13514.1 - 1.6e-20 71.5 3.3 2.7e-05 23.9 0.1 5.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 ABX13514.1 - 2.6e-17 62.9 0.8 1.8e-08 34.5 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 ABX13514.1 - 8.3e-17 59.9 2.6 0.002 18.0 0.0 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 ABX13514.1 - 2e-15 55.6 14.1 0.00012 22.0 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 ABX13514.1 - 3.7e-13 49.1 0.0 0.00054 20.6 0.0 5.3 2 1 4 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 ABX13514.1 - 1.1e-12 47.4 3.7 0.00013 22.1 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ABX13514.1 - 1.6e-12 47.7 0.7 3.3e-05 24.3 0.1 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 ABX13514.1 - 8.4e-11 41.4 0.9 0.00071 19.4 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ABX13514.1 - 4e-09 37.0 0.0 2.4e-06 28.1 0.0 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ABX13514.1 - 7.2e-09 35.8 11.0 0.00027 21.1 0.4 3.1 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 ABX13514.1 - 1.7e-08 34.0 4.3 7.5e-06 25.5 0.1 4.6 3 1 1 4 4 4 1 TPR repeat TPR_9 PF13371.6 ABX13514.1 - 3.4e-07 30.3 0.0 0.00014 21.9 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 ABX13514.1 - 4.3e-07 29.2 0.7 4.3e-07 29.2 0.7 2.1 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 DUF4919 PF16266.5 ABX13514.1 - 7.3e-07 29.3 3.1 0.048 13.6 0.1 3.2 1 1 2 3 3 3 3 Domain of unknown function (DUF4919) Fis1_TPR_C PF14853.6 ABX13514.1 - 2.5e-06 27.5 6.2 6.3 7.0 0.1 5.2 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 ABX13514.1 - 6.6e-06 25.5 0.4 1.8e-05 24.1 0.2 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 ABX13514.1 - 1e-05 25.8 0.8 2 9.2 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 ABX13514.1 - 0.00043 20.8 0.7 0.42 11.1 0.1 2.6 1 1 0 2 2 2 2 Alkyl sulfatase dimerisation BTAD PF03704.17 ABX13514.1 - 0.0015 19.0 0.1 0.0064 16.9 0.1 2.0 1 1 1 2 2 2 1 Bacterial transcriptional activator domain Rapsyn_N PF10579.9 ABX13514.1 - 0.0027 17.7 0.1 0.11 12.6 0.0 3.0 3 1 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region SRP_TPR_like PF17004.5 ABX13514.1 - 0.0028 17.7 9.4 0.0091 16.0 3.8 2.7 1 1 1 3 3 3 1 Putative TPR-like repeat Coatomer_E PF04733.14 ABX13514.1 - 0.0035 16.8 3.8 0.27 10.6 0.7 2.2 1 1 1 2 2 2 2 Coatomer epsilon subunit Cas_Cas02710 PF09670.10 ABX13514.1 - 0.0097 14.8 1.3 0.022 13.6 0.8 1.8 1 1 1 2 2 2 1 CRISPR-associated protein (Cas_Cas02710) MIT PF04212.18 ABX13514.1 - 0.014 15.5 15.1 2.3 8.3 0.0 4.2 3 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 ABX13514.1 - 0.017 15.5 0.2 2.1 8.7 0.2 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.20 ABX13514.1 - 0.029 14.3 11.7 0.12 12.2 8.4 2.5 1 1 3 4 4 4 0 Region in Clathrin and VPS PPTA PF01239.22 ABX13514.1 - 0.079 12.7 0.6 0.83 9.5 0.1 3.0 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat MSA-2c PF12238.8 ABX13514.1 - 0.98 9.4 5.8 0.91 9.5 2.4 2.1 1 1 1 2 2 2 0 Merozoite surface antigen 2c Response_reg PF00072.24 ABX13515.1 - 9e-21 74.2 0.4 9.9e-21 74.0 0.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Pyr_redox PF00070.27 ABX13515.1 - 0.0043 17.6 0.0 7.1 7.3 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ABX13515.1 - 0.04 13.2 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2608 PF11019.8 ABX13515.1 - 0.067 12.7 0.9 0.64 9.5 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2608) TrkA_N PF02254.18 ABX13515.1 - 0.15 12.3 2.9 2.1 8.6 2.9 2.7 1 1 0 1 1 1 0 TrkA-N domain TrmB PF01978.19 ABX13516.1 - 0.05 13.5 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HpcH_HpaI PF03328.14 ABX13517.1 - 4.3e-49 166.6 0.0 5.3e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ABX13517.1 - 1.2e-16 60.8 1.0 1.9e-08 33.9 0.2 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 ABX13517.1 - 5.4e-05 22.2 1.5 7.5e-05 21.8 1.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Exog_C PF18026.1 ABX13517.1 - 0.0032 17.5 0.8 0.089 12.9 0.5 2.7 2 0 0 2 2 2 1 Endo/exonuclease (EXOG) C-terminal domain ADH_zinc_N PF00107.26 ABX13518.1 - 4.9e-26 91.2 0.0 8e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABX13518.1 - 1.4e-20 73.2 0.1 2.2e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ABX13518.1 - 3.3e-17 63.8 0.1 5.7e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ABX13518.1 - 0.018 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ACP_syn_III_C PF08541.10 ABX13518.1 - 0.16 12.2 0.3 0.49 10.6 0.1 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal dsDNA_bind PF01984.20 ABX13519.1 - 6.2e-25 87.6 0.9 6.9e-25 87.5 0.9 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Ribosomal_S19e PF01090.19 ABX13520.1 - 3.2e-48 162.9 0.0 3.7e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e EMG1 PF03587.14 ABX13521.1 - 1.8e-37 128.9 0.3 2e-37 128.7 0.3 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyco_transf_4 PF13439.6 ABX13521.1 - 0.058 13.4 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DUF3258 PF11646.8 ABX13521.1 - 0.3 11.3 2.7 0.4 10.8 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF3258 Glyco_hydro_42 PF02449.15 ABX13522.1 - 6e-05 22.5 0.0 0.0049 16.2 0.0 2.1 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.19 ABX13522.1 - 6.8e-05 22.6 0.1 0.0099 15.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Phage_Arf PF17585.2 ABX13522.1 - 0.02 14.8 0.4 4.3 7.4 0.0 2.7 2 0 0 2 2 2 0 Accessory recombination function protein End_beta_barrel PF12195.8 ABX13522.1 - 0.13 12.3 0.1 5.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase Ribonuc_red_lgC PF02867.15 ABX13523.1 - 4.9e-182 606.1 0.0 7.3e-182 605.5 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 ABX13523.1 - 1.6e-32 111.4 0.0 3.8e-32 110.1 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 ABX13523.1 - 2.4e-21 76.1 0.6 9.3e-21 74.2 0.6 2.1 1 0 0 1 1 1 1 ATP cone domain HEPN_RES_NTD1 PF18870.1 ABX13523.1 - 0.36 11.0 2.5 14 5.9 0.0 3.7 4 0 0 4 4 4 0 HEPN/RES N-terminal domain 1 NRDD PF13597.6 ABX13524.1 - 1e-27 97.2 0.0 2.2e-20 73.0 0.0 2.3 2 0 0 2 2 2 2 Anaerobic ribonucleoside-triphosphate reductase HTH_20 PF12840.7 ABX13524.1 - 5.4e-10 39.2 0.0 1.3e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain ATP-cone PF03477.16 ABX13524.1 - 5.6e-06 26.9 1.9 1.3e-05 25.6 0.0 2.6 3 0 0 3 3 3 1 ATP cone domain Lig_C PF18330.1 ABX13524.1 - 0.005 16.8 1.0 0.33 11.0 0.0 3.2 3 0 0 3 3 3 1 Ligase Pab1020 C-terminal region TackOD1 PF18551.1 ABX13524.1 - 0.26 10.9 1.6 0.38 10.4 0.2 1.9 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 ABX13525.1 - 0.00019 21.4 0.5 0.00025 21.0 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 ABX13525.1 - 0.00027 20.5 2.9 0.14 11.9 0.3 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 ABX13525.1 - 0.00055 19.2 3.0 0.096 12.1 0.3 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zf-LITAF-like PF10601.9 ABX13525.1 - 0.00085 19.5 0.2 1.1 9.6 0.0 2.2 2 0 0 2 2 2 2 LITAF-like zinc ribbon domain TF_Zn_Ribbon PF08271.12 ABX13525.1 - 0.002 17.6 1.6 0.22 11.1 0.2 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding HypA PF01155.19 ABX13525.1 - 0.0028 17.7 0.2 0.003 17.6 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 ABX13525.1 - 0.0028 17.2 1.0 1.4 8.6 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 ABX13525.1 - 0.0036 17.6 1.7 0.17 12.2 0.3 1.9 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Chordopox_RPO7 PF05864.12 ABX13525.1 - 0.0053 17.0 0.5 0.032 14.5 0.5 2.1 1 1 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zf-TFIIB PF13453.6 ABX13525.1 - 0.0078 15.5 1.0 0.035 13.4 0.2 2.0 2 0 0 2 2 2 1 Transcription factor zinc-finger FANCL_C PF11793.8 ABX13525.1 - 0.0088 16.2 1.5 0.049 13.8 1.4 1.9 1 1 1 2 2 2 1 FANCL C-terminal domain zf-C4_Topoisom PF01396.19 ABX13525.1 - 0.011 15.5 3.4 0.29 10.9 0.3 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_4 PF13717.6 ABX13525.1 - 0.011 15.6 2.6 0.53 10.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 ABX13525.1 - 0.014 15.5 1.8 0.057 13.6 1.8 1.8 1 1 0 1 1 1 0 Zinc ribbon domain DUF4428 PF14471.6 ABX13525.1 - 0.015 15.3 4.5 1.2 9.1 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-ACC PF17848.1 ABX13525.1 - 0.016 15.2 2.3 0.28 11.3 0.2 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain YhfH PF14149.6 ABX13525.1 - 0.019 14.9 4.5 2.3 8.3 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein DiS_P_DiS PF06750.13 ABX13525.1 - 0.02 15.0 0.9 0.11 12.6 0.9 1.8 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Sgf11 PF08209.11 ABX13525.1 - 0.027 14.0 0.7 2.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF983 PF06170.12 ABX13525.1 - 0.027 14.9 0.1 9.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) LIM PF00412.22 ABX13525.1 - 0.028 14.7 0.1 0.056 13.7 0.1 1.5 1 1 0 1 1 1 0 LIM domain DUF4796 PF16044.5 ABX13525.1 - 0.037 13.6 0.5 0.77 9.3 0.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4796) zf-DNA_Pol PF08996.10 ABX13525.1 - 0.049 13.4 0.5 0.05 13.3 0.5 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-C2HC5 PF06221.13 ABX13525.1 - 0.053 13.5 2.5 0.16 12.0 2.5 1.7 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_5 PF13719.6 ABX13525.1 - 0.056 13.2 2.0 1.9 8.3 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 ABX13525.1 - 0.058 13.4 1.4 1.2 9.2 1.5 2.1 1 1 0 1 1 1 0 zinc-ribbons zf-dskA_traR PF01258.17 ABX13525.1 - 0.058 13.3 0.6 6.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-ISL3 PF14690.6 ABX13525.1 - 0.065 13.9 0.5 7.1 7.4 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2 PF00096.26 ABX13525.1 - 0.13 12.7 2.4 5.4 7.7 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Rubredoxin_2 PF18073.1 ABX13525.1 - 0.2 11.4 5.1 0.21 11.3 0.8 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain Cript PF10235.9 ABX13525.1 - 0.2 12.3 4.1 0.48 11.0 4.1 1.6 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT TFIIS_C PF01096.18 ABX13525.1 - 0.22 11.4 3.2 7.7 6.5 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_ribbon_SprT PF17283.2 ABX13525.1 - 0.29 11.1 3.0 2.2 8.3 0.1 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain CpXC PF14353.6 ABX13525.1 - 0.34 10.9 2.9 7.4 6.7 0.2 2.1 1 1 1 2 2 2 0 CpXC protein zf-NADH-PPase PF09297.11 ABX13525.1 - 0.38 10.5 4.3 5.6 6.7 0.3 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain OrfB_Zn_ribbon PF07282.11 ABX13525.1 - 0.49 10.4 4.7 1.6 8.7 0.4 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain ADK_lid PF05191.14 ABX13525.1 - 0.99 9.4 5.3 9.1 6.4 5.2 2.0 1 1 1 2 2 2 0 Adenylate kinase, active site lid OB_aCoA_assoc PF01796.17 ABX13526.1 - 2.7e-08 33.7 0.2 3.8e-08 33.2 0.2 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 ABX13526.1 - 2.1e-05 24.3 0.2 2.9e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 ABX13526.1 - 0.00026 20.6 3.4 0.00043 19.9 3.4 1.4 1 0 0 1 1 1 1 zinc-ribbon domain PHF5 PF03660.14 ABX13526.1 - 0.008 16.4 0.7 0.011 16.0 0.7 1.2 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.7 ABX13526.1 - 0.0082 16.1 1.5 0.013 15.5 1.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon TackOD1 PF18551.1 ABX13526.1 - 0.011 15.4 1.3 0.015 14.9 1.3 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zinc_ribbon_15 PF17032.5 ABX13526.1 - 0.077 13.8 2.1 0.11 13.3 2.1 1.2 1 0 0 1 1 1 0 zinc-ribbon family RNHCP PF12647.7 ABX13526.1 - 0.21 11.6 0.4 0.21 11.6 0.4 1.8 1 1 1 2 2 2 0 RNHCP domain CpXC PF14353.6 ABX13526.1 - 0.29 11.2 1.8 0.65 10.1 1.8 1.6 1 1 0 1 1 1 0 CpXC protein zf-C2H2_11 PF16622.5 ABX13526.1 - 0.3 10.9 2.9 4.3 7.2 0.3 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Rubredoxin_2 PF18073.1 ABX13526.1 - 0.39 10.5 5.2 4.1 7.2 5.4 2.1 1 1 1 2 2 2 0 Rubredoxin metal binding domain Thiolase_N PF00108.23 ABX13527.1 - 1.1e-20 74.2 0.0 3e-20 72.7 0.0 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABX13527.1 - 9.9e-12 44.6 1.3 9.1e-10 38.2 0.0 3.2 2 2 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ABX13527.1 - 3.4e-05 23.6 0.1 0.05 13.2 0.0 3.0 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ABX13527.1 - 0.057 13.4 1.0 2.5 8.1 0.1 3.3 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain zf-C4_Topoisom PF01396.19 ABX13528.1 - 1.3e-06 28.1 10.2 5e-06 26.2 1.1 2.8 2 1 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger Ogr_Delta PF04606.12 ABX13528.1 - 0.02 14.9 11.1 1 9.4 1.8 3.5 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger Zn_ribbon_recom PF13408.6 ABX13528.1 - 0.32 11.5 7.2 0.93 10.1 0.5 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain CN_hydrolase PF00795.22 ABX13529.1 - 1.6e-56 191.6 0.0 1.8e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BRCT_2 PF16589.5 ABX13529.1 - 0.05 14.0 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain DUF5304 PF17230.2 ABX13529.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5304) Tautomerase PF01361.21 ABX13530.1 - 5.2e-15 55.1 0.0 5.5e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.6 ABX13530.1 - 8.1e-07 29.1 0.0 8.4e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_3 PF14832.6 ABX13530.1 - 0.026 14.8 0.0 0.027 14.7 0.0 1.0 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme Rhomboid PF01694.22 ABX13531.1 - 2.1e-35 122.0 19.6 2.1e-35 122.0 19.6 1.6 2 0 0 2 2 2 1 Rhomboid family Copper-bind PF00127.20 ABX13533.1 - 1.5e-06 28.5 0.0 5.9e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX13533.1 - 0.00014 21.9 0.0 0.00097 19.2 0.0 2.4 2 0 0 2 2 2 1 Cupredoxin-like domain DUF87 PF01935.17 ABX13535.1 - 0.094 12.8 1.7 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain DUF2663 PF10864.8 ABX13536.1 - 0.021 15.2 1.0 0.081 13.3 1.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2663) Ets PF00178.22 ABX13536.1 - 0.18 12.3 1.3 0.33 11.4 0.6 1.8 2 0 0 2 2 2 0 Ets-domain DUF4381 PF14316.6 ABX13536.1 - 0.18 12.0 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF5638 PF18688.1 ABX13536.1 - 1.9 8.8 6.9 7.4 6.9 2.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5638) VWA PF00092.28 ABX13537.1 - 6.3e-22 78.7 0.1 8e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ABX13537.1 - 3e-21 76.1 0.0 4.8e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain BatA PF07584.11 ABX13537.1 - 2.8e-07 30.8 0.1 2.8e-07 30.8 0.1 1.7 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal Ssl1 PF04056.14 ABX13537.1 - 0.00021 21.1 0.0 0.0099 15.7 0.0 2.1 2 0 0 2 2 2 1 Ssl1-like VWA_3 PF13768.6 ABX13537.1 - 0.00022 21.2 0.0 0.00055 19.9 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 ABX13537.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DUF1194 PF06707.11 ABX13537.1 - 0.04 13.1 0.1 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) DUF58 PF01882.18 ABX13538.1 - 7.7e-23 80.6 0.0 1.3e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF58 VWA_2 PF13519.6 ABX13538.1 - 5.9e-10 39.8 0.1 1.5e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain PPIP5K2_N PF18086.1 ABX13538.1 - 0.062 13.5 0.3 0.15 12.2 0.3 1.6 1 0 0 1 1 1 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Suppressor_P21 PF11479.8 ABX13538.1 - 0.45 10.7 4.7 0.28 11.4 0.3 2.9 4 0 0 4 4 4 0 RNA silencing suppressor P21 C-terminal domain AAA_3 PF07726.11 ABX13539.1 - 1.3e-62 209.4 0.1 2.4e-62 208.6 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 ABX13539.1 - 4.2e-20 71.4 0.0 1.4e-19 69.7 0.0 1.8 2 0 0 2 2 2 1 AAA lid domain AAA_5 PF07728.14 ABX13539.1 - 4.5e-11 42.9 0.0 9.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 ABX13539.1 - 1.5e-05 24.2 0.0 2.9e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 ABX13539.1 - 9.4e-05 22.2 0.0 0.00028 20.6 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 ABX13539.1 - 0.0019 18.0 0.3 0.025 14.3 0.1 2.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 ABX13539.1 - 0.0033 17.8 0.2 0.018 15.5 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ABX13539.1 - 0.0048 16.3 2.2 0.048 13.0 0.1 2.6 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI Lgl_C PF08596.10 ABX13539.1 - 0.071 11.8 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal DUF2393 PF09624.10 ABX13540.1 - 0.22 11.5 2.0 0.45 10.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2393) HTH_24 PF13412.6 ABX13541.1 - 1.3e-17 63.1 0.2 1.5e-08 34.0 0.1 2.5 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 ABX13541.1 - 5.9e-12 45.3 0.1 5.8e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 ABX13541.1 - 8e-09 35.3 0.1 9e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 MarR family TrmB PF01978.19 ABX13541.1 - 3.9e-08 33.0 0.2 0.00011 22.0 0.2 2.3 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 ABX13541.1 - 3.2e-07 30.2 0.0 0.0048 16.8 0.0 2.4 2 0 0 2 2 2 2 MarR family HTH_45 PF14947.6 ABX13541.1 - 1.1e-06 28.6 0.0 0.06 13.3 0.0 2.2 2 0 0 2 2 2 2 Winged helix-turn-helix HTH_20 PF12840.7 ABX13541.1 - 3e-06 27.2 0.0 0.001 19.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Rrf2 PF02082.20 ABX13541.1 - 5e-06 26.8 0.1 0.019 15.3 0.0 2.3 2 0 0 2 2 2 2 Transcriptional regulator HTH_IclR PF09339.10 ABX13541.1 - 6.2e-06 25.9 0.0 0.022 14.5 0.0 2.2 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_34 PF13601.6 ABX13541.1 - 0.00012 22.2 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 2 Winged helix DNA-binding domain LexA_DNA_bind PF01726.16 ABX13541.1 - 0.00093 18.9 0.1 0.068 13.0 0.0 2.6 2 1 0 2 2 2 1 LexA DNA binding domain HTH_Crp_2 PF13545.6 ABX13541.1 - 0.0018 18.2 0.1 0.37 10.8 0.0 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain B-block_TFIIIC PF04182.12 ABX13541.1 - 0.0052 16.9 0.1 0.31 11.2 0.1 2.2 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC Penicillinase_R PF03965.16 ABX13541.1 - 0.008 16.5 0.0 2.4 8.5 0.1 2.6 1 1 1 2 2 2 1 Penicillinase repressor Fe_dep_repress PF01325.19 ABX13541.1 - 0.01 16.0 0.2 0.048 13.9 0.1 1.9 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_40 PF14493.6 ABX13541.1 - 0.011 16.1 0.0 0.55 10.7 0.0 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain ANAPC2 PF08672.11 ABX13541.1 - 0.016 15.7 0.2 3.5 8.2 0.0 3.1 2 1 1 3 3 3 0 Anaphase promoting complex (APC) subunit 2 Cdc6_C PF09079.11 ABX13541.1 - 0.025 14.5 0.0 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain RPA_C PF08784.11 ABX13541.1 - 0.027 15.1 0.0 11 6.7 0.0 2.3 2 0 0 2 2 2 0 Replication protein A C terminal DUF2250 PF10007.9 ABX13541.1 - 0.028 14.5 0.3 1.7 8.8 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Mnd1 PF03962.15 ABX13541.1 - 0.061 13.6 7.1 0.56 10.5 0.2 4.0 2 2 2 4 4 4 0 Mnd1 HTH domain RP-C PF03428.13 ABX13541.1 - 0.062 13.0 0.0 0.35 10.5 0.0 1.9 2 0 0 2 2 2 0 Replication protein C N-terminal domain DprA_WH PF17782.1 ABX13541.1 - 0.07 13.3 0.0 5.7 7.1 0.1 2.4 2 1 0 2 2 2 0 DprA winged helix domain PCI PF01399.27 ABX13541.1 - 0.089 13.3 0.0 0.16 12.5 0.0 1.6 1 1 0 1 1 1 0 PCI domain RNA_pol_Rpc34 PF05158.12 ABX13541.1 - 0.11 11.8 0.4 0.54 9.6 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpc34 subunit EIIC-GAT PF03611.14 ABX13542.1 - 0.034 13.2 4.2 0.037 13.1 4.2 1.1 1 0 0 1 1 1 0 PTS system sugar-specific permease component NVEALA PF14055.6 ABX13542.1 - 0.051 13.6 0.8 0.063 13.3 0.0 1.5 2 0 0 2 2 2 0 NVEALA protein PTS_EIIC_2 PF13303.6 ABX13542.1 - 0.066 12.2 4.1 0.071 12.1 4.1 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC GOLD_2 PF13897.6 ABX13543.1 - 0.084 13.4 4.1 1.6 9.2 0.2 3.1 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking ABC2_membrane PF01061.24 ABX13545.1 - 0.049 13.0 0.4 0.13 11.6 0.1 1.8 2 0 0 2 2 2 0 ABC-2 type transporter Cupredoxin_1 PF13473.6 ABX13546.1 - 4e-05 23.7 0.0 0.00022 21.3 0.0 2.2 2 1 0 2 2 2 1 Cupredoxin-like domain Copper-bind PF00127.20 ABX13546.1 - 0.036 14.5 0.1 0.11 13.0 0.0 1.9 2 1 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family SGL PF08450.12 ABX13548.1 - 2.2e-14 53.6 0.5 0.08 12.5 0.0 5.2 2 1 3 5 5 5 4 SMP-30/Gluconolactonase/LRE-like region CopD PF05425.13 ABX13548.1 - 3.8e-13 49.7 0.6 3.8e-13 49.7 0.6 2.6 2 1 1 3 3 3 1 Copper resistance protein D CopC PF04234.12 ABX13548.1 - 7.1e-09 36.6 0.0 1.6e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 CopC domain DUF5074 PF16819.5 ABX13548.1 - 2.8e-06 27.3 4.6 0.28 11.3 0.1 4.9 4 1 1 5 5 5 3 Domain of unknown function (DUF5074) Reg_prop PF07494.11 ABX13548.1 - 0.0029 17.6 16.3 5.8 7.5 0.0 7.3 8 0 0 8 8 8 2 Two component regulator propeller DUF4149 PF13664.6 ABX13548.1 - 0.022 15.1 1.9 0.022 15.1 1.9 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) PPC PF04151.15 ABX13548.1 - 0.046 14.8 3.2 0.078 14.1 1.0 2.5 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Phytase-like PF13449.6 ABX13548.1 - 0.084 12.8 0.6 5.7 6.8 0.4 3.0 1 1 1 2 2 2 0 Esterase-like activity of phytase Y_Y_Y PF07495.13 ABX13548.1 - 0.22 11.5 0.7 0.94 9.5 0.1 2.4 2 0 0 2 2 2 0 Y_Y_Y domain ABC-3 PF00950.17 ABX13549.1 - 2.2e-62 210.9 37.1 2.7e-62 210.6 37.1 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 ABX13549.1 - 3.6e-06 26.2 35.6 9.2e-06 24.9 35.4 1.7 1 1 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 ABX13550.1 - 1.4e-33 116.3 0.0 4.2e-33 114.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ABX13550.1 - 2.4e-11 44.0 2.8 2.4e-05 24.3 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ABX13550.1 - 8.1e-07 29.7 0.9 1.4e-06 29.0 0.9 1.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 ABX13550.1 - 2.9e-06 26.9 1.2 5.1e-05 22.8 1.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABX13550.1 - 4e-05 23.3 0.0 7.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 ABX13550.1 - 7e-05 22.6 0.2 0.13 12.0 0.0 2.8 2 1 1 3 3 3 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ABX13550.1 - 0.0051 16.7 0.0 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 ABX13550.1 - 0.0085 16.4 0.1 0.02 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 ABX13550.1 - 0.025 14.8 0.0 0.89 9.8 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 ABX13550.1 - 0.048 13.2 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ABX13550.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_13 PF13166.6 ABX13550.1 - 0.091 11.4 2.8 0.82 8.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ABX13550.1 - 0.095 12.9 0.0 0.38 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ABX13550.1 - 0.11 12.8 0.0 0.42 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 ABX13550.1 - 0.13 12.0 4.1 0.25 11.0 4.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ZnuA PF01297.17 ABX13551.1 - 3.7e-70 236.3 1.6 4.2e-70 236.1 1.6 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic NikR_C PF08753.11 ABX13552.1 - 2.3e-11 43.7 2.3 3.5e-11 43.1 2.3 1.3 1 0 0 1 1 1 1 NikR C terminal nickel binding domain RHH_1 PF01402.21 ABX13552.1 - 7.3e-06 25.7 0.1 1.3e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family VapB_antitoxin PF09957.9 ABX13552.1 - 0.0035 17.2 0.0 0.0077 16.1 0.0 1.6 1 1 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB DUF3920 PF13058.6 ABX13552.1 - 0.043 14.0 0.1 0.051 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) Tsc35 PF15079.6 ABX13553.1 - 0.046 13.3 4.8 0.056 13.0 4.8 1.0 1 0 0 1 1 1 0 Testis-specific protein 35 TMEM72 PF16054.5 ABX13553.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein family 72 RRF PF01765.19 ABX13553.1 - 0.13 12.2 0.4 0.15 12.0 0.4 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Thioredoxin_4 PF13462.6 ABX13554.1 - 2.6e-36 125.3 0.0 3.4e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ABX13554.1 - 4.6e-19 69.0 0.1 2.1e-12 47.2 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ABX13554.1 - 9.2e-09 35.7 0.2 3.8e-08 33.8 0.1 2.0 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 ABX13554.1 - 2.6e-05 24.0 0.1 6e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin DUF929 PF06053.11 ABX13554.1 - 0.019 14.3 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Thioredoxin_3 PF13192.6 ABX13554.1 - 0.064 13.3 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin domain SurA_N_3 PF13624.6 ABX13554.1 - 0.073 12.9 0.3 0.14 11.9 0.2 1.5 2 0 0 2 2 2 0 SurA N-terminal domain ADP_PFK_GK PF04587.15 ABX13554.1 - 0.15 10.6 0.1 0.4 9.2 0.0 1.6 2 0 0 2 2 2 0 ADP-specific Phosphofructokinase/Glucokinase conserved region zf-H2C2_2 PF13465.6 ABX13554.1 - 0.19 12.2 1.1 0.42 11.1 1.1 1.5 1 0 0 1 1 1 0 Zinc-finger double domain Usp PF00582.26 ABX13555.1 - 1.4e-27 96.9 0.0 1.7e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family DUF4055 PF13264.6 ABX13555.1 - 0.15 12.2 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Sortilin-Vps10 PF15902.5 ABX13556.1 - 6.2e-15 54.9 0.0 1.5e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, PSII_BNR PF14870.6 ABX13556.1 - 2.9e-06 26.8 9.2 0.018 14.3 0.7 3.9 1 1 2 3 3 3 2 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 ABX13556.1 - 0.0015 18.3 18.0 1.3 9.3 0.1 5.7 5 0 0 5 5 5 3 BNR/Asp-box repeat SGL PF08450.12 ABX13556.1 - 0.0027 17.3 0.1 0.035 13.7 0.0 2.5 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PrgH PF09480.10 ABX13556.1 - 0.014 14.7 0.0 4.3 6.5 0.0 2.1 2 0 0 2 2 2 0 Type III secretion system protein PrgH-EprH (PrgH) DUF5643 PF18705.1 ABX13556.1 - 0.042 13.8 0.7 0.58 10.1 0.0 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5643) PD40 PF07676.12 ABX13556.1 - 0.05 13.6 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat HxlR PF01638.17 ABX13557.1 - 3.4e-22 78.1 0.0 4.3e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 ABX13557.1 - 5e-05 23.2 0.1 7.6e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 ABX13557.1 - 0.00057 19.8 0.0 0.00095 19.0 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 ABX13557.1 - 0.0034 16.9 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_12 PF08461.10 ABX13557.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_20 PF12840.7 ABX13557.1 - 0.023 14.7 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_45 PF14947.6 ABX13557.1 - 0.04 13.9 0.1 0.067 13.2 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_34 PF13601.6 ABX13557.1 - 0.081 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Replic_Relax PF13814.6 ABX13557.1 - 0.081 13.0 0.0 0.087 12.9 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation HTH_Crp_2 PF13545.6 ABX13557.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Zip PF02535.22 ABX13558.1 - 0.00059 19.1 15.5 0.00059 19.1 15.5 3.0 1 1 1 2 2 2 1 ZIP Zinc transporter PIRT PF15099.6 ABX13558.1 - 0.034 13.7 5.3 0.15 11.7 0.2 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Cu-oxidase_3 PF07732.15 ABX13559.1 - 2.5e-24 85.6 3.3 7e-20 71.2 0.3 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ABX13559.1 - 5.3e-22 78.0 7.0 3.6e-11 42.9 0.2 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 ABX13559.1 - 0.11 12.6 0.0 23 5.2 0.0 2.8 3 0 0 3 3 3 0 Cupredoxin-like domain Fe_dep_repress PF01325.19 ABX13560.1 - 8.9e-22 77.1 0.2 1.8e-21 76.1 0.2 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.15 ABX13560.1 - 2.7e-13 49.8 0.0 5.7e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain MarR_2 PF12802.7 ABX13560.1 - 5.6e-05 22.9 0.0 9.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ABX13560.1 - 0.00012 21.9 0.0 0.00033 20.5 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 ABX13560.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_45 PF14947.6 ABX13560.1 - 0.0014 18.5 0.2 0.0035 17.3 0.1 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix LexA_DNA_bind PF01726.16 ABX13560.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 LexA DNA binding domain HTH_micro PF17007.5 ABX13560.1 - 0.0021 17.0 0.1 0.0028 16.6 0.1 1.3 1 1 0 1 1 1 1 HTH-like DUF2250 PF10007.9 ABX13560.1 - 0.047 13.8 1.9 0.18 12.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_6 PF01418.17 ABX13560.1 - 0.056 13.4 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_27 PF13463.6 ABX13560.1 - 0.057 13.9 0.0 0.19 12.2 0.0 2.0 2 1 0 2 2 2 0 Winged helix DNA-binding domain TrmB PF01978.19 ABX13560.1 - 0.066 13.1 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HipN PF18253.1 ABX13560.1 - 0.071 12.8 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain Copper-bind PF00127.20 ABX13561.1 - 1.7e-08 34.8 0.0 3.1e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX13561.1 - 0.00015 21.9 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain Kelch_1 PF01344.25 ABX13562.1 - 1.2e-47 159.2 1.1 9.9e-10 37.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 ABX13562.1 - 5.2e-37 124.9 10.2 5.1e-09 36.1 0.1 6.9 3 2 4 7 7 7 6 Kelch motif Kelch_2 PF07646.15 ABX13562.1 - 1.1e-31 107.6 0.5 1.1e-05 25.2 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 ABX13562.1 - 3.3e-28 97.2 2.4 7.8e-05 22.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 ABX13562.1 - 3.8e-24 84.4 12.7 1.8e-06 28.1 0.0 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 ABX13562.1 - 4.1e-23 81.1 9.3 2.8e-05 24.0 0.1 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain PQQ_3 PF13570.6 ABX13562.1 - 0.003 18.0 0.3 31 5.2 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Head_binding PF09008.10 ABX13562.1 - 0.0089 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Head binding Cu-oxidase_3 PF07732.15 ABX13563.1 - 7.1e-12 45.4 1.6 9.1e-10 38.6 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase PHINT_rpt PF14882.6 ABX13564.1 - 9.9e-12 44.9 9.7 0.0018 18.5 0.2 3.4 3 0 0 3 3 3 3 Phage-integrase repeat unit DUF2717 PF10911.8 ABX13564.1 - 0.00099 18.8 0.1 4.2 7.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2717) DUF3757 PF12582.8 ABX13564.1 - 0.0052 17.2 2.2 0.29 11.6 0.1 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3757) DUF4131 PF13567.6 ABX13565.1 - 0.021 14.5 1.4 0.6 9.7 0.1 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) TPR_21 PF09976.9 ABX13565.1 - 0.044 13.5 0.1 0.078 12.7 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain YtkA PF13115.6 ABX13565.1 - 0.15 12.6 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 YtkA-like UPF0697 PF15117.6 ABX13565.1 - 0.66 10.1 3.1 1.6 8.8 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 Thioredoxin_4 PF13462.6 ABX13566.1 - 1.6e-40 138.9 0.0 2.1e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ABX13566.1 - 6.2e-19 68.5 0.2 6.2e-11 42.4 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ABX13566.1 - 2.3e-09 37.7 0.7 5.7e-09 36.4 0.7 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 ABX13566.1 - 0.0042 16.8 0.1 0.0058 16.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin DUF929 PF06053.11 ABX13566.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF309 PF03745.14 ABX13566.1 - 0.19 11.5 1.0 3.5 7.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF309) SGL PF08450.12 ABX13567.1 - 8.2e-09 35.4 0.6 0.39 10.3 0.1 4.6 2 2 2 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 ABX13567.1 - 0.00033 20.5 1.5 0.031 14.3 0.1 3.6 4 0 0 4 4 4 1 NHL repeat Phytase-like PF13449.6 ABX13567.1 - 0.0019 18.2 0.0 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 Esterase-like activity of phytase Reg_prop PF07494.11 ABX13567.1 - 0.0062 16.6 6.8 49 4.6 0.2 6.1 6 0 0 6 6 6 0 Two component regulator propeller FixG_C PF11614.8 ABX13567.1 - 0.073 13.3 0.6 0.2 11.9 0.6 1.8 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Trypsin_2 PF13365.6 ABX13569.1 - 7.8e-33 114.5 0.7 1.2e-32 113.9 0.7 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 ABX13569.1 - 6.2e-13 48.9 1.8 1.1e-12 48.0 0.5 2.1 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 ABX13569.1 - 2.8e-12 46.9 0.7 7.5e-12 45.5 0.7 1.7 1 1 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 ABX13569.1 - 0.00034 20.4 1.3 0.028 14.2 0.3 2.9 3 0 0 3 3 3 1 PDZ domain Peptidase_S29 PF02907.15 ABX13569.1 - 0.00043 20.0 0.1 0.00075 19.3 0.1 1.4 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Tricorn_PDZ PF14685.6 ABX13569.1 - 0.07 13.1 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 ABX13569.1 - 0.082 11.5 2.0 0.14 10.8 0.3 1.8 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S32 PF05579.13 ABX13569.1 - 0.087 12.0 4.9 1.7 7.8 0.1 2.4 2 1 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 PDZ PF00595.24 ABX13569.1 - 0.18 12.2 5.2 24 5.4 3.3 3.3 2 1 0 2 2 2 0 PDZ domain HTH_24 PF13412.6 ABX13570.1 - 6.5e-16 57.6 0.3 1.7e-08 33.9 0.0 3.5 3 0 0 3 3 3 3 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABX13570.1 - 1.5e-11 44.0 0.0 0.00086 19.1 0.0 3.5 3 1 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ABX13570.1 - 1.3e-09 37.7 0.0 0.00036 20.3 0.0 3.2 3 0 0 3 3 3 3 IclR helix-turn-helix domain HTH_5 PF01022.20 ABX13570.1 - 5e-08 32.7 0.1 0.13 12.1 0.0 3.3 3 0 0 3 3 3 3 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABX13570.1 - 3.3e-07 30.3 0.0 0.019 15.0 0.0 3.2 3 0 0 3 3 3 2 Helix-turn-helix domain MarR_2 PF12802.7 ABX13570.1 - 8.7e-07 28.7 0.0 0.04 13.8 0.0 2.5 3 0 0 3 3 2 2 MarR family MarR PF01047.22 ABX13570.1 - 2.8e-05 24.0 1.0 0.43 10.5 0.0 3.4 3 0 0 3 3 3 2 MarR family HTH_34 PF13601.6 ABX13570.1 - 0.00055 20.1 0.1 2.6 8.3 0.0 3.1 3 0 0 3 3 3 2 Winged helix DNA-binding domain FUR PF01475.19 ABX13570.1 - 0.017 15.2 0.1 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Ferric uptake regulator family HTH_36 PF13730.6 ABX13570.1 - 0.02 14.8 1.0 1.9 8.5 0.1 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain Rrf2 PF02082.20 ABX13570.1 - 0.02 15.2 0.3 18 5.8 0.0 3.1 3 0 0 3 3 3 0 Transcriptional regulator DUF4423 PF14394.6 ABX13570.1 - 0.057 13.1 0.1 0.75 9.5 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4423) HTH_11 PF08279.12 ABX13570.1 - 0.068 13.1 0.1 0.24 11.4 0.1 2.0 2 0 0 2 2 2 0 HTH domain DUF742 PF05331.11 ABX13570.1 - 0.093 12.6 0.0 0.51 10.2 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF742) HTH_23 PF13384.6 ABX13570.1 - 0.1 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain 7TMR-DISM_7TM PF07695.11 ABX13571.1 - 0.11 12.4 11.7 0.19 11.6 11.7 1.4 1 1 0 1 1 1 0 7TM diverse intracellular signalling YpmT PF17431.2 ABX13571.1 - 0.16 12.0 0.3 0.16 12.0 0.3 2.5 3 0 0 3 3 3 0 Uncharacterized YmpT-like DUF5373 PF17343.2 ABX13571.1 - 0.72 9.7 9.5 0.51 10.2 7.7 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5373) TssN PF17555.2 ABX13571.1 - 3.4 7.0 11.3 4.9 6.4 11.3 1.3 1 1 0 1 1 1 0 Type VI secretion system, TssN DUF4231 PF14015.6 ABX13571.1 - 4.2 7.9 6.7 1.3 9.6 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) hSac2 PF12456.8 ABX13573.1 - 0.027 14.2 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Inositol phosphatase MHYT PF03707.16 ABX13573.1 - 0.054 13.7 0.1 0.087 13.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Copper-bind PF00127.20 ABX13574.1 - 3.1e-07 30.7 0.0 7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 ABX13574.1 - 0.1 12.7 0.0 0.71 10.0 0.0 2.4 1 1 0 1 1 1 0 Cupredoxin-like domain EamA PF00892.20 ABX13576.1 - 2.9e-40 137.6 42.6 2.1e-21 76.5 14.6 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 ABX13576.1 - 3.2e-05 23.4 23.0 0.0023 17.3 12.0 2.5 1 1 2 3 3 3 2 Triose-phosphate Transporter family DUF3272 PF11676.8 ABX13576.1 - 0.094 13.0 1.9 0.29 11.4 0.3 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3272) TCR_zetazeta PF11628.8 ABX13576.1 - 1.1 9.0 7.6 27 4.6 0.0 3.7 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 zeta chain TMEM234 PF10639.9 ABX13576.1 - 3.1 7.9 13.2 2.5 8.1 1.8 2.6 2 1 0 2 2 2 0 Putative transmembrane family 234 UPF0060 PF02694.15 ABX13577.1 - 3.9e-40 136.4 8.9 4.6e-40 136.2 8.9 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family EamA PF00892.20 ABX13577.1 - 0.00091 19.4 11.8 0.0051 17.0 11.8 2.1 1 1 0 1 1 1 1 EamA-like transporter family Phage_holin_2_4 PF16082.5 ABX13577.1 - 0.013 15.2 0.8 0.013 15.2 0.8 1.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like BaxI_1 PF12811.7 ABX13577.1 - 0.035 13.7 4.0 0.045 13.3 4.0 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF2631 PF10939.8 ABX13577.1 - 0.058 13.3 0.3 0.17 11.8 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) MFS_1 PF07690.16 ABX13577.1 - 0.088 11.7 12.0 0.79 8.6 12.0 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF3611 PF12263.8 ABX13577.1 - 3.5 7.5 7.0 4.4 7.2 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) DUF3784 PF12650.7 ABX13577.1 - 6.8 7.0 11.4 0.42 10.8 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) UPF0060 PF02694.15 ABX13578.1 - 6.9e-37 126.0 7.5 7.8e-37 125.8 7.5 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family MFS_1 PF07690.16 ABX13578.1 - 0.00035 19.6 4.4 0.0048 15.9 0.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EamA PF00892.20 ABX13578.1 - 0.0018 18.4 3.3 0.0035 17.5 3.3 1.5 1 1 0 1 1 1 1 EamA-like transporter family 7TMR-DISM_7TM PF07695.11 ABX13578.1 - 0.0024 17.8 3.4 0.006 16.5 3.4 1.7 1 1 0 1 1 1 1 7TM diverse intracellular signalling COX14 PF14880.6 ABX13578.1 - 1.6 8.6 7.5 0.25 11.2 1.0 2.6 2 1 0 2 2 2 0 Cytochrome oxidase c assembly AAA PF00004.29 ABX13579.1 - 1.1e-07 32.4 0.0 2.8e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 ABX13579.1 - 2.6e-07 30.5 0.0 1.2e-06 28.3 0.0 2.1 2 0 0 2 2 1 1 CDC6, C terminal winged helix domain AAA_16 PF13191.6 ABX13579.1 - 8.5e-06 26.3 0.2 0.00024 21.5 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ABX13579.1 - 2.1e-05 24.8 0.0 4.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ABX13579.1 - 0.0026 18.3 0.1 0.0094 16.5 0.1 2.2 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 ABX13579.1 - 0.0026 17.0 0.0 0.0046 16.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain DUF815 PF05673.13 ABX13579.1 - 0.0028 16.9 0.0 0.013 14.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.6 ABX13579.1 - 0.0028 18.2 1.6 0.012 16.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 ABX13579.1 - 0.014 15.3 5.6 0.15 11.9 3.3 2.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ABX13579.1 - 0.016 15.6 0.1 0.3 11.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 ABX13579.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ABX13579.1 - 0.031 14.0 0.1 0.072 12.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 ABX13579.1 - 0.031 14.3 0.1 0.076 13.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 ABX13579.1 - 0.039 14.3 0.1 0.092 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA C-terminal domain NTPase_1 PF03266.15 ABX13579.1 - 0.059 13.3 0.0 0.29 11.0 0.0 2.1 3 0 0 3 3 2 0 NTPase NACHT PF05729.12 ABX13579.1 - 0.076 12.9 0.1 0.35 10.8 0.0 2.2 2 1 0 2 2 2 0 NACHT domain Phage-MuB_C PF09077.11 ABX13579.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Mu B transposition protein, C terminal Rrf2 PF02082.20 ABX13579.1 - 0.14 12.5 0.1 0.54 10.6 0.0 2.1 2 0 0 2 2 1 0 Transcriptional regulator RsgA_GTPase PF03193.16 ABX13579.1 - 0.14 12.0 0.5 1.3 8.9 0.1 2.6 2 1 1 3 3 3 0 RsgA GTPase LON_substr_bdg PF02190.16 ABX13581.1 - 2.3e-07 30.9 0.0 3.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DUF1002 PF06207.11 ABX13581.1 - 0.059 12.9 0.1 0.083 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) SLBP_RNA_bind PF15247.6 ABX13581.1 - 0.089 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain OTCace_N PF02729.21 ABX13582.1 - 1.4e-41 142.0 0.0 2e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 ABX13582.1 - 2.4e-28 99.2 0.0 3.5e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PyrI PF01948.18 ABX13583.1 - 1e-31 109.0 3.7 1.5e-31 108.5 3.7 1.3 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.15 ABX13583.1 - 1.2e-13 50.7 1.3 1.2e-13 50.7 1.3 1.6 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF1936 PF09151.10 ABX13583.1 - 0.044 13.7 0.4 0.096 12.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) ATP-synt_C PF00137.21 ABX13584.1 - 1.9e-16 60.1 16.3 1.9e-16 60.1 16.3 1.9 2 0 0 2 2 2 1 ATP synthase subunit C ATP-synt_D PF01813.17 ABX13585.1 - 2.8e-47 161.1 6.5 3.1e-47 160.9 6.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit D ATP-synt_ab PF00006.25 ABX13586.1 - 3.8e-70 235.9 0.0 5.3e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ABX13586.1 - 1.1e-11 45.1 1.3 2.7e-11 43.8 1.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 ABX13586.1 - 0.0011 19.1 0.8 0.0048 17.0 0.5 2.3 2 0 0 2 2 2 1 HAS barrel domain ATP-synt_ab PF00006.25 ABX13587.1 - 5e-94 313.9 0.0 6.9e-94 313.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 ABX13587.1 - 3.5e-42 143.1 0.0 6.7e-42 142.2 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 ABX13587.1 - 4.8e-14 52.6 0.4 1.3e-13 51.2 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Biotin_lipoyl PF00364.22 ABX13587.1 - 0.014 15.2 0.4 3.6 7.5 0.0 2.8 2 0 0 2 2 2 0 Biotin-requiring enzyme AAA_22 PF13401.6 ABX13587.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.12 ABX13587.1 - 0.084 11.4 0.2 0.18 10.4 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RnfC_N PF13375.6 ABX13587.1 - 0.22 11.5 0.8 30 4.6 0.2 2.7 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain vATP-synt_E PF01991.18 ABX13588.1 - 2.4e-21 76.1 7.6 7.4e-21 74.5 7.4 1.9 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit OSCP PF00213.18 ABX13588.1 - 0.0018 18.4 6.3 0.0032 17.6 6.3 1.5 1 1 0 1 1 1 1 ATP synthase delta (OSCP) subunit RHD3 PF05879.12 ABX13588.1 - 0.024 12.8 2.7 0.024 12.8 2.7 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Ribosomal_L17 PF01196.19 ABX13588.1 - 0.031 15.2 1.0 0.069 14.0 0.2 1.9 1 1 1 2 2 2 0 Ribosomal protein L17 Cluap1 PF10234.9 ABX13588.1 - 0.032 13.6 2.6 0.051 13.0 2.6 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 Muted PF14942.6 ABX13588.1 - 0.034 14.5 3.2 0.061 13.7 3.2 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein MukF_M PF17192.4 ABX13588.1 - 0.042 13.6 1.5 0.066 13.0 1.5 1.3 1 0 0 1 1 1 0 MukF middle domain DASH_Spc19 PF08287.11 ABX13588.1 - 0.053 13.4 2.3 0.12 12.2 2.2 1.6 1 1 0 1 1 1 0 Spc19 Perilipin PF03036.16 ABX13588.1 - 0.11 11.5 3.2 0.15 11.0 2.7 1.6 1 1 0 1 1 1 0 Perilipin family YkyA PF10368.9 ABX13588.1 - 0.15 11.8 7.9 0.23 11.1 7.9 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein HrpE PF06188.12 ABX13588.1 - 0.15 11.9 1.8 7.1 6.5 0.1 2.2 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E Prominin PF05478.11 ABX13588.1 - 0.19 9.7 2.6 0.23 9.4 2.6 1.1 1 0 0 1 1 1 0 Prominin HAUS-augmin3 PF14932.6 ABX13588.1 - 0.31 10.6 3.9 0.39 10.3 3.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 ABX13588.1 - 0.37 10.1 4.2 0.5 9.7 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ParB PF08775.10 ABX13588.1 - 0.67 10.4 4.8 0.48 10.9 2.5 2.0 1 1 1 2 2 2 0 ParB family Ribosomal_S30AE PF02482.19 ABX13588.1 - 0.74 10.6 4.3 29 5.5 2.2 3.0 2 2 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein V_ATPase_I PF01496.19 ABX13589.1 - 5.6e-26 90.8 10.2 6.9e-21 73.9 0.0 3.2 3 0 0 3 3 3 3 V-type ATPase 116kDa subunit family HHH_9 PF17674.1 ABX13589.1 - 0.86 10.6 2.7 0.89 10.5 0.4 2.2 2 0 0 2 2 2 0 HHH domain APG6_N PF17675.1 ABX13589.1 - 3.7 8.1 6.4 15 6.2 1.0 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region GAF_2 PF13185.6 ABX13591.1 - 6.1e-17 62.2 0.0 1e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ABX13591.1 - 6.1e-11 43.1 0.0 1e-10 42.4 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 ABX13591.1 - 7.2e-07 29.6 0.0 1.2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 GAF domain HTH_12 PF08461.10 ABX13591.1 - 0.00027 20.8 0.2 0.0006 19.7 0.2 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_WhiA PF02650.14 ABX13591.1 - 0.0019 18.5 0.7 0.99 9.8 0.0 2.6 2 0 0 2 2 2 2 WhiA C-terminal HTH domain HTH_AsnC-type PF13404.6 ABX13591.1 - 0.0041 16.9 0.7 0.028 14.2 1.3 2.1 2 1 0 2 2 2 1 AsnC-type helix-turn-helix domain DUF3658 PF12395.8 ABX13591.1 - 0.0059 16.5 0.6 0.098 12.6 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function Gp_dh_C PF02800.20 ABX13591.1 - 0.0082 15.7 0.0 0.027 14.1 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain BAR_3 PF16746.5 ABX13591.1 - 0.036 13.8 1.9 0.038 13.7 0.9 1.7 2 0 0 2 2 2 0 BAR domain of APPL family HTH_24 PF13412.6 ABX13591.1 - 0.054 13.1 2.7 0.75 9.4 2.7 2.6 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding Nitroreductase PF00881.24 ABX13592.1 - 4.6e-37 127.7 0.0 5.5e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABX13592.1 - 7.8e-10 38.7 0.1 3.1e-05 23.6 0.0 3.0 2 1 1 3 3 3 3 Putative TM nitroreductase Rhodanese PF00581.20 ABX13593.1 - 1.1e-39 135.3 0.0 4.3e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain APP_N PF02177.16 ABX13593.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Ammonium_transp PF00909.21 ABX13594.1 - 4.8e-107 358.1 35.6 1.3e-106 356.7 35.6 1.6 1 1 0 1 1 1 1 Ammonium Transporter Family LegC3_N PF18654.1 ABX13595.1 - 0.017 14.4 1.2 0.017 14.4 1.2 1.5 1 1 0 1 1 1 0 LegC3 N-terminal coiled-coil domain OSCP PF00213.18 ABX13595.1 - 0.098 12.8 3.3 0.13 12.3 3.3 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit vATP-synt_AC39 PF01992.16 ABX13596.1 - 2e-52 178.8 5.0 2.5e-52 178.4 5.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Poly_export PF02563.16 ABX13596.1 - 0.075 13.3 0.2 4.5 7.6 0.0 2.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein Fibritin_C PF07921.12 ABX13596.1 - 0.094 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Fibritin C-terminal region Cas_Cas4 PF01930.17 ABX13597.1 - 9.1e-05 22.6 0.7 0.00014 22.0 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 ABX13597.1 - 0.21 11.5 2.3 5.7 6.8 0.4 2.1 1 1 1 2 2 2 0 PD-(D/E)XK nuclease superfamily LGT PF01790.18 ABX13598.1 - 0.031 13.5 0.6 0.031 13.5 0.6 1.0 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase Myco_arth_vir_N PF09610.10 ABX13599.1 - 0.11 12.6 0.5 0.11 12.6 0.5 1.7 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Glyco_trans_1_2 PF13524.6 ABX13600.1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferases group 1 AA_kinase PF00696.28 ABX13601.1 - 2.4e-29 102.7 1.0 3.5e-29 102.1 1.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family DUF5567 PF17722.1 ABX13601.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5567) HD PF01966.22 ABX13602.1 - 1.2e-17 64.2 0.8 2.8e-17 63.1 0.4 1.9 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 ABX13602.1 - 0.051 13.1 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 HDOD domain Thymidylate_kin PF02223.17 ABX13603.1 - 2.3e-37 128.5 1.5 2.5e-37 128.3 1.5 1.0 1 0 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 ABX13603.1 - 0.022 14.6 5.7 0.38 10.6 5.7 2.3 1 1 0 1 1 1 0 Deoxynucleoside kinase PutA_N PF18083.1 ABX13603.1 - 0.08 13.0 0.4 0.2 11.7 0.0 1.9 2 1 0 2 2 2 0 Proline utilization A N-terminal domain 6PF2K PF01591.18 ABX13603.1 - 0.086 12.1 3.2 0.19 11.0 0.0 2.3 2 2 0 2 2 2 0 6-phosphofructo-2-kinase TIMP PF00965.17 ABX13603.1 - 0.13 12.1 0.6 0.26 11.1 0.6 1.4 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase DUF3619 PF12279.8 ABX13603.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Imm26 PF15428.6 ABX13603.1 - 0.18 12.0 3.5 0.85 9.9 0.8 2.2 2 0 0 2 2 2 0 Immunity protein 26 DUF2634 PF10934.8 ABX13603.1 - 0.22 11.7 0.2 0.22 11.7 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2634) DUF2183 PF09949.9 ABX13603.1 - 0.49 10.8 4.3 0.57 10.5 0.9 2.5 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2183) RNase_J_C PF17770.1 ABX13603.1 - 0.86 10.7 5.3 6.4 7.9 2.3 2.4 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain HSP20 PF00011.21 ABX13604.1 - 2.6e-12 46.8 0.3 3.2e-12 46.5 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ABX13604.1 - 1e-08 34.6 0.2 4.6e-08 32.5 0.1 2.2 1 1 1 2 2 2 1 HSP20-like domain found in ArsA TubC_N PF18563.1 ABX13604.1 - 0.0023 17.9 0.4 0.011 15.7 0.1 2.0 2 0 0 2 2 2 1 TubC N-terminal docking domain ABC1 PF03109.16 ABX13605.1 - 4e-25 88.3 0.3 1.8e-24 86.2 0.0 2.0 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 ABX13605.1 - 0.021 14.2 0.5 0.04 13.3 0.5 1.4 1 0 0 1 1 1 0 Protein kinase domain DUF4795 PF16043.5 ABX13605.1 - 0.021 14.4 0.1 0.021 14.4 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) APH PF01636.23 ABX13605.1 - 0.036 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2207 PF09972.9 ABX13605.1 - 0.074 11.8 2.4 0.095 11.4 0.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF483 PF04467.12 ABX13605.1 - 0.1 12.6 0.1 0.56 10.2 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF483) USP8_dimer PF08969.11 ABX13605.1 - 0.1 12.8 3.0 5.5 7.2 0.2 2.8 2 0 0 2 2 2 0 USP8 dimerisation domain DUF1282 PF06930.12 ABX13606.1 - 0.071 12.9 0.0 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) AgrD PF05931.11 ABX13606.1 - 0.11 12.5 0.7 0.35 10.9 0.3 2.0 2 0 0 2 2 2 0 Staphylococcal AgrD protein HemX PF04375.14 ABX13607.1 - 0.0032 16.8 3.4 0.0038 16.6 3.4 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF1043 PF06295.12 ABX13607.1 - 0.004 17.1 4.9 0.028 14.4 1.8 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1043) End3 PF12761.7 ABX13607.1 - 0.0053 17.0 8.6 0.0058 16.8 8.6 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 THUMP PF02926.17 ABX13607.1 - 0.0079 16.3 1.3 0.0096 16.0 1.3 1.2 1 0 0 1 1 1 1 THUMP domain DUF4709 PF15821.5 ABX13607.1 - 0.011 16.0 3.8 0.014 15.7 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) Baculo_p24 PF05073.12 ABX13607.1 - 0.013 15.2 4.0 0.016 15.0 4.0 1.1 1 0 0 1 1 1 0 Baculovirus P24 capsid protein RAC_head PF16717.5 ABX13607.1 - 0.014 16.4 4.6 0.019 15.9 4.6 1.2 1 0 0 1 1 1 0 Ribosome-associated complex head domain MitMem_reg PF13012.6 ABX13607.1 - 0.015 15.7 2.2 0.02 15.3 2.2 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function CorA PF01544.18 ABX13607.1 - 0.017 14.5 2.0 0.02 14.2 2.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Spc7 PF08317.11 ABX13607.1 - 0.019 13.8 11.7 0.023 13.6 11.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein BMFP PF04380.13 ABX13607.1 - 0.02 15.4 3.6 0.031 14.8 3.6 1.4 1 0 0 1 1 1 0 Membrane fusogenic activity Allexi_40kDa PF05549.11 ABX13607.1 - 0.025 14.1 4.1 0.028 14.0 4.1 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Mrpl_C PF18502.1 ABX13607.1 - 0.03 14.6 3.3 0.042 14.1 3.3 1.3 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain Ax_dynein_light PF10211.9 ABX13607.1 - 0.047 13.6 8.0 0.056 13.4 8.0 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain IATP PF04568.12 ABX13607.1 - 0.058 13.8 0.8 0.08 13.4 0.8 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP SOAR PF16533.5 ABX13607.1 - 0.071 13.1 3.3 0.092 12.7 3.3 1.2 1 0 0 1 1 1 0 STIM1 Orai1-activating region KxDL PF10241.9 ABX13607.1 - 0.08 13.2 6.6 0.33 11.3 1.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein Exonuc_VII_L PF02601.15 ABX13607.1 - 0.1 12.1 3.2 0.12 11.9 3.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2935 PF11155.8 ABX13607.1 - 0.11 12.8 3.1 0.15 12.4 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Peptidase_M24_C PF16188.5 ABX13607.1 - 0.12 12.5 1.8 0.17 12.0 1.3 1.7 2 1 0 2 2 1 0 C-terminal region of peptidase_M24 AI-2E_transport PF01594.16 ABX13607.1 - 0.17 11.0 1.1 0.19 10.9 1.1 1.2 1 0 0 1 1 1 0 AI-2E family transporter TMPIT PF07851.13 ABX13607.1 - 0.18 11.0 4.7 0.22 10.7 4.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Arch_flagellin PF01917.16 ABX13607.1 - 0.18 11.9 3.4 6.4 6.9 0.5 2.1 1 1 0 2 2 2 0 Archaebacterial flagellin DUF3040 PF11239.8 ABX13607.1 - 0.23 11.8 1.5 12 6.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DASH_Duo1 PF08651.10 ABX13607.1 - 0.26 11.1 8.5 0.44 10.3 2.2 2.2 1 1 1 2 2 2 0 DASH complex subunit Duo1 ABC2_membrane_3 PF12698.7 ABX13607.1 - 0.28 10.3 1.7 0.31 10.1 1.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein HIP1_clath_bdg PF16515.5 ABX13607.1 - 0.51 11.0 9.2 1.5 9.5 9.2 1.7 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-C4H2 PF10146.9 ABX13607.1 - 0.52 10.6 10.2 0.68 10.2 10.2 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein YojJ PF10372.9 ABX13607.1 - 0.78 9.9 7.9 9.2 6.4 3.5 3.0 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus Fib_alpha PF08702.10 ABX13607.1 - 1 9.5 10.0 1.3 9.2 10.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Tho2 PF11262.8 ABX13607.1 - 1.4 8.0 8.2 1.7 7.8 8.2 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 O-antigen_lig PF13425.6 ABX13607.1 - 1.7 7.3 5.5 1.8 7.2 5.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3450 PF11932.8 ABX13607.1 - 4 6.7 12.2 16 4.7 12.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Gal4_dimer PF03902.13 ABX13607.1 - 4.4 7.6 5.9 3.8 7.8 2.7 2.5 2 1 0 2 2 2 0 Gal4-like dimerisation domain SlyX PF04102.12 ABX13607.1 - 4.4 8.0 8.9 3.4 8.3 7.0 1.8 1 1 1 2 2 2 0 SlyX DUF1664 PF07889.12 ABX13607.1 - 6.5 6.8 9.3 3.5 7.7 7.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) NPCBM_assoc PF10633.9 ABX13608.1 - 0.00035 20.7 0.9 1.2 9.4 0.0 3.9 3 1 1 4 4 4 2 NPCBM-associated, NEW3 domain of alpha-galactosidase EPSP_synthase PF00275.20 ABX13608.1 - 0.0014 17.4 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DUF11 PF01345.18 ABX13608.1 - 0.016 15.5 3.1 2.5 8.5 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF11 ABC_tran PF00005.27 ABX13609.1 - 5.2e-33 114.5 0.2 8e-33 113.9 0.2 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ABX13609.1 - 1.4e-05 24.7 5.0 0.00037 20.0 5.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ABX13609.1 - 1.6e-05 24.9 1.2 0.024 14.4 0.9 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABX13609.1 - 3e-05 23.7 0.4 0.00014 21.5 0.3 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ABX13609.1 - 5.3e-05 23.7 0.2 0.00015 22.2 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ABX13609.1 - 0.0004 20.7 0.4 0.0072 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 ABX13609.1 - 0.00058 19.7 0.6 0.0063 16.3 0.2 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 ABX13609.1 - 0.0008 18.2 0.5 0.038 12.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ABX13609.1 - 0.00081 19.3 1.4 0.001 19.0 0.1 1.9 3 0 0 3 3 2 1 RsgA GTPase G-alpha PF00503.20 ABX13609.1 - 0.0021 17.3 0.0 0.0025 17.1 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit ATPase_2 PF01637.18 ABX13609.1 - 0.0071 16.3 0.2 0.04 13.8 0.0 2.0 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 ABX13609.1 - 0.0077 15.1 1.1 0.043 12.6 0.1 2.2 2 1 0 2 2 2 1 Predicted ATPase of the ABC class DNA_gyraseA_C PF03989.13 ABX13609.1 - 0.0087 15.5 0.2 0.016 14.7 0.2 1.5 1 0 0 1 1 1 1 DNA gyrase C-terminal domain, beta-propeller AAA_23 PF13476.6 ABX13609.1 - 0.01 16.4 2.3 0.016 15.7 2.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 ABX13609.1 - 0.011 14.7 0.2 0.028 13.3 0.1 1.6 1 1 1 2 2 2 0 AAA-like domain Zeta_toxin PF06414.12 ABX13609.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 ABX13609.1 - 0.015 14.9 0.6 0.088 12.4 0.1 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 ABX13609.1 - 0.015 15.2 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 ABX13609.1 - 0.022 14.8 1.8 0.046 13.8 1.8 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ABX13609.1 - 0.023 14.4 0.9 0.039 13.7 0.2 1.8 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 ABX13609.1 - 0.024 14.0 0.4 0.84 8.9 0.1 2.2 2 0 0 2 2 2 0 KaiC Dynamin_N PF00350.23 ABX13609.1 - 0.03 14.4 1.2 0.24 11.5 0.2 2.1 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 ABX13609.1 - 0.03 13.7 1.6 0.062 12.6 0.3 2.0 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 ABX13609.1 - 0.046 13.9 1.0 0.071 13.3 1.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ABX13609.1 - 0.056 13.0 0.2 0.71 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ABX13609.1 - 0.057 12.5 0.6 0.08 12.0 0.1 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 ABX13609.1 - 0.058 13.1 0.6 0.53 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ABX13609.1 - 0.062 13.2 0.6 0.15 11.9 0.2 1.9 2 1 1 3 3 2 0 NACHT domain AAA_14 PF13173.6 ABX13609.1 - 0.086 12.9 0.1 0.19 11.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 ABX13609.1 - 0.088 13.2 0.0 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase CRISPR_Cas9_WED PF18061.1 ABX13609.1 - 0.13 12.3 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain MacB_PCD PF12704.7 ABX13610.1 - 1.2e-16 61.7 2.3 1.9e-16 61.0 2.3 1.3 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.21 ABX13610.1 - 2.1e-14 53.8 1.4 2.1e-14 53.8 1.4 2.2 2 0 0 2 2 2 1 FtsX-like permease family DUF4064 PF13273.6 ABX13610.1 - 2.6 8.4 16.7 1.4 9.2 2.0 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF4064) HTH_24 PF13412.6 ABX13611.1 - 2.9e-21 74.7 5.5 3.3e-11 42.6 0.4 2.7 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ABX13611.1 - 1.8e-19 69.3 0.4 6.9e-11 41.8 0.1 2.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 ABX13611.1 - 1.6e-07 31.2 0.4 0.018 15.0 0.0 2.9 2 0 0 2 2 2 2 HTH domain MarR_2 PF12802.7 ABX13611.1 - 4.1e-07 29.8 0.0 0.031 14.2 0.0 2.3 2 0 0 2 2 2 2 MarR family TrmB PF01978.19 ABX13611.1 - 4.5e-06 26.5 0.0 0.032 14.1 0.0 2.4 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_Mga PF08280.11 ABX13611.1 - 5.4e-06 26.4 7.7 0.0031 17.5 1.2 4.3 4 0 0 4 4 4 1 M protein trans-acting positive regulator (MGA) HTH domain MarR PF01047.22 ABX13611.1 - 1.3e-05 25.0 2.3 0.0068 16.3 0.2 2.9 3 0 0 3 3 3 2 MarR family HTH_23 PF13384.6 ABX13611.1 - 7.4e-05 22.4 0.0 0.044 13.6 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain GerE PF00196.19 ABX13611.1 - 0.00013 21.5 0.3 0.27 10.8 0.4 2.9 2 0 0 2 2 2 2 Bacterial regulatory proteins, luxR family Mga PF05043.13 ABX13611.1 - 0.00013 22.5 2.6 0.023 15.3 0.3 3.3 3 1 1 4 4 3 1 Mga helix-turn-helix domain HTH_5 PF01022.20 ABX13611.1 - 0.0002 21.2 0.4 0.38 10.7 0.1 2.6 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family RepL PF05732.11 ABX13611.1 - 0.00066 19.1 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 1 Firmicute plasmid replication protein (RepL) Trp_repressor PF01371.19 ABX13611.1 - 0.0023 18.0 0.5 0.034 14.3 0.1 2.7 2 1 0 2 2 2 1 Trp repressor protein HTH_7 PF02796.15 ABX13611.1 - 0.0048 17.0 0.6 0.053 13.6 0.2 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 ABX13611.1 - 0.0076 16.3 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_DeoR PF08220.12 ABX13611.1 - 0.024 14.4 0.5 1.6 8.6 0.1 2.7 3 0 0 3 3 2 0 DeoR-like helix-turn-helix domain Sigma70_r4 PF04545.16 ABX13611.1 - 0.025 14.1 0.3 0.13 11.8 0.1 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_6 PF01418.17 ABX13611.1 - 0.058 13.4 0.1 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_40 PF14493.6 ABX13611.1 - 0.059 13.8 0.1 0.24 11.9 0.1 2.0 2 0 0 2 2 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 ABX13611.1 - 0.073 12.9 1.3 4.4 7.2 0.0 3.0 3 0 0 3 3 3 0 TFIIE alpha subunit Rnk_N PF14760.6 ABX13611.1 - 0.074 13.6 0.2 8.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Rnk N-terminus DUF1563 PF07599.11 ABX13611.1 - 0.088 12.9 1.6 0.11 12.6 0.1 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1563) HTH_27 PF13463.6 ABX13611.1 - 0.092 13.2 0.1 3.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_29 PF13551.6 ABX13611.1 - 0.1 12.6 0.0 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix HTH_50 PF18024.1 ABX13611.1 - 0.11 12.2 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain RuvB_C PF05491.13 ABX13611.1 - 0.8 9.6 3.1 2.1 8.3 0.3 3.0 3 1 0 3 3 3 0 RuvB C-terminal winged helix domain NUDIX PF00293.28 ABX13612.1 - 3.7e-18 65.8 0.0 4.9e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain PhoU PF01895.19 ABX13613.1 - 4.3e-10 39.9 4.5 2.5e-07 31.1 2.1 2.8 2 0 0 2 2 2 2 PhoU domain MazE_antitoxin PF04014.18 ABX13613.1 - 9e-05 22.3 0.1 0.0002 21.2 0.1 1.6 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin GHMP_kinases_N PF00288.26 ABX13614.1 - 1e-11 44.9 0.3 1.8e-11 44.1 0.3 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain ACT_7 PF13840.6 ABX13614.1 - 0.044 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 ACT domain GHMP_kinases_C PF08544.13 ABX13614.1 - 0.048 14.0 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 GHMP kinases C terminal PPS_PS PF02006.16 ABX13615.1 - 1.8e-72 242.6 5.6 2.3e-72 242.2 5.6 1.1 1 0 0 1 1 1 1 Phosphopantothenate/pantothenate synthetase Orexin_rec2 PF03827.13 ABX13615.1 - 0.018 15.0 2.3 3.9 7.6 0.1 2.7 2 1 1 3 3 3 0 Orexin receptor type 2 TPP_enzyme_M PF00205.22 ABX13615.1 - 0.034 13.9 0.9 0.085 12.6 0.2 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain HicB_lk_antitox PF15919.5 ABX13615.1 - 0.089 12.9 0.8 0.18 11.9 0.3 1.8 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system MatP_C PF17414.2 ABX13615.1 - 0.48 10.7 3.6 4.2 7.6 1.0 2.6 1 1 1 2 2 2 0 MatP C-terminal ribbon-helix-helix domain Pantoate_transf PF02548.15 ABX13616.1 - 7.8e-107 356.5 3.7 8.8e-107 356.3 3.7 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 ABX13616.1 - 0.00048 19.7 0.5 0.0014 18.1 0.2 1.8 1 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DFP PF04127.15 ABX13617.1 - 1.6e-60 204.2 5.8 1.3e-58 197.9 3.4 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 ABX13617.1 - 1.5e-36 125.6 2.1 5e-36 123.8 0.1 2.3 2 1 0 2 2 2 1 Flavoprotein NAD_binding_7 PF13241.6 ABX13617.1 - 0.00019 21.8 1.4 0.11 13.0 0.1 3.1 2 1 0 2 2 2 2 Putative NAD(P)-binding YjeF_N PF03853.15 ABX13617.1 - 0.0048 16.8 0.5 1.7 8.5 0.0 2.9 2 1 0 2 2 2 2 YjeF-related protein N-terminus BRCT PF00533.26 ABX13617.1 - 0.087 13.2 3.0 0.85 10.0 0.0 3.2 3 1 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Methyltransf_25 PF13649.6 ABX13618.1 - 8.2e-18 64.9 0.0 1.5e-16 60.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABX13618.1 - 3.8e-17 62.5 0.0 6.2e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABX13618.1 - 5.2e-17 62.3 0.0 1.3e-15 57.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABX13618.1 - 6e-16 58.5 0.1 4e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ABX13618.1 - 1e-09 38.5 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABX13618.1 - 4e-09 37.1 0.0 8.7e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ABX13618.1 - 7.4e-07 29.1 0.0 1.9e-06 27.8 0.0 1.6 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ABX13618.1 - 5.2e-06 26.1 0.1 1e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 ABX13618.1 - 5.5e-06 26.1 0.0 7.8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 ABX13618.1 - 4.7e-05 22.6 0.2 0.00022 20.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase CheR PF01739.18 ABX13618.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CMAS PF02353.20 ABX13618.1 - 0.006 15.9 0.0 0.0086 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 ABX13618.1 - 0.0071 15.8 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 ABX13618.1 - 0.0083 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Fibrillarin PF01269.17 ABX13618.1 - 0.042 12.9 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin MetW PF07021.12 ABX13618.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Asparaginase_2 PF01112.18 ABX13618.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Asparaginase YebF PF13995.6 ABX13619.1 - 0.0024 17.8 0.9 0.0038 17.2 0.9 1.3 1 0 0 1 1 1 1 YebF-like protein Peptidase_M24 PF00557.24 ABX13620.1 - 5e-57 193.0 0.0 6.3e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ABX13620.1 - 1e-14 55.3 0.0 1.7e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DYW_deaminase PF14432.6 ABX13620.1 - 0.035 14.0 0.9 6.4 6.7 0.1 3.1 3 0 0 3 3 3 0 DYW family of nucleic acid deaminases DrrA_P4M PF14860.6 ABX13620.1 - 0.24 11.3 4.4 0.68 9.8 1.3 2.5 2 1 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain NFACT-R_2 PF18297.1 ABX13621.1 - 5.3e-24 84.4 0.1 9.4e-24 83.6 0.1 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain ThiI PF02568.14 ABX13621.1 - 4.9e-12 45.9 0.0 9.3e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 ABX13621.1 - 4.1e-09 35.7 0.0 1.6e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 ABX13621.1 - 0.014 14.9 0.1 0.035 13.6 0.1 1.6 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NFACT-R_1 PF05670.13 ABX13621.1 - 0.019 15.6 0.0 0.042 14.5 0.0 1.6 1 0 0 1 1 1 0 NFACT protein RNA binding domain Asn_synthase PF00733.21 ABX13621.1 - 0.092 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase SepF PF04472.12 ABX13622.1 - 1.4e-11 44.5 0.9 1.6e-11 44.3 0.9 1.1 1 0 0 1 1 1 1 Cell division protein SepF Herpes_IE68 PF02479.16 ABX13622.1 - 0.012 15.2 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus immediate early protein H_kinase_N PF12282.8 ABX13622.1 - 0.016 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Signal transduction histidine kinase SporV_AA PF12164.8 ABX13622.1 - 0.055 13.8 0.8 0.077 13.4 0.8 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AA Beta-Casp PF10996.8 ABX13623.1 - 1.1e-22 80.4 0.0 2.2e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain KH_7 PF17214.3 ABX13623.1 - 5e-22 77.6 1.5 8.2e-21 73.7 0.7 2.9 3 0 0 3 3 3 1 KH domain RMMBL PF07521.12 ABX13623.1 - 2e-15 56.4 0.0 4.4e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 ABX13623.1 - 8.9e-13 48.1 0.0 1.8e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 ABX13623.1 - 1.1e-12 48.4 0.1 2.5e-11 44.0 0.1 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ABX13623.1 - 7.5e-11 41.9 0.0 2.7e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ABX13623.1 - 0.027 14.4 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Proteasome PF00227.26 ABX13624.1 - 1.7e-52 177.6 0.3 2e-52 177.5 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Fe-ADH_2 PF13685.6 ABX13625.1 - 2.2e-71 240.5 0.5 2.9e-71 240.1 0.5 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 ABX13625.1 - 6.8e-24 84.3 0.2 1.4e-22 80.0 0.2 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 ABX13625.1 - 5e-06 25.9 0.1 0.00015 21.0 0.1 2.7 1 1 0 1 1 1 1 3-dehydroquinate synthase MSV199 PF10553.9 ABX13625.1 - 0.048 13.9 0.3 0.099 12.9 0.3 1.5 1 0 0 1 1 1 0 MSV199 domain FKBP26_C PF18046.1 ABX13626.1 - 2.4e-12 46.7 1.0 6.3e-12 45.4 1.0 1.7 1 0 0 1 1 1 1 FKBP26_C-terminal FKBP_C PF00254.28 ABX13626.1 - 7.5e-12 45.4 0.3 4.1e-11 43.1 0.1 2.1 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase CAP_GLY PF01302.25 ABX13626.1 - 0.0045 17.0 0.0 0.0089 16.0 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Aminotran_5 PF00266.19 ABX13627.1 - 9.4e-39 133.4 0.0 1.2e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ABX13627.1 - 9.1e-05 21.1 0.3 0.00014 20.5 0.3 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fiji_64_capsid PF05880.11 ABX13627.1 - 0.027 13.1 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein CTP_transf_like PF01467.26 ABX13628.1 - 2e-13 50.8 0.0 3.3e-13 50.0 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase-like RTC PF01137.21 ABX13629.1 - 1.5e-75 253.3 0.0 1.6e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase CopD PF05425.13 ABX13630.1 - 6.3e-14 52.3 1.3 6.3e-14 52.3 1.3 1.7 2 0 0 2 2 2 1 Copper resistance protein D DUF2269 PF10027.9 ABX13630.1 - 0.00047 20.2 7.8 0.00061 19.9 7.8 1.1 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) UPF0093 PF03653.13 ABX13630.1 - 0.0024 18.1 9.2 0.0061 16.8 9.2 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0093) Ytp1 PF10355.9 ABX13630.1 - 0.012 14.8 1.7 0.015 14.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) SieB PF14163.6 ABX13630.1 - 0.013 14.9 10.2 0.02 14.4 3.9 2.4 2 1 0 2 2 2 0 Super-infection exclusion protein B Urate_ox_N PF06181.11 ABX13630.1 - 0.031 13.6 0.8 0.031 13.6 0.8 1.8 1 1 0 1 1 1 0 Urate oxidase N-terminal DUF1772 PF08592.11 ABX13630.1 - 0.051 13.9 0.3 0.079 13.3 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF3278 PF11683.8 ABX13630.1 - 0.057 13.5 2.7 0.12 12.5 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) AGP PF06376.12 ABX13630.1 - 0.078 12.8 1.4 0.078 12.8 1.4 2.3 3 1 0 3 3 3 0 Arabinogalactan peptide Aa_trans PF01490.18 ABX13630.1 - 0.18 10.5 9.0 0.036 12.8 2.5 2.0 1 1 1 2 2 2 0 Transmembrane amino acid transporter protein DUF4149 PF13664.6 ABX13630.1 - 0.38 11.1 7.6 0.15 12.4 3.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DHHC PF01529.20 ABX13630.1 - 2.1 8.4 5.4 2 8.5 0.7 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase Brr6_like_C_C PF10104.9 ABX13630.1 - 3.4 7.5 6.2 0.49 10.2 1.3 2.1 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain LEA_2 PF03168.13 ABX13631.1 - 0.15 12.6 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein Nitroreductase PF00881.24 ABX13632.1 - 6e-26 91.5 0.0 9.8e-26 90.8 0.0 1.3 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABX13632.1 - 0.00042 19.9 0.6 0.18 11.3 0.0 3.0 2 1 1 3 3 3 3 Putative TM nitroreductase FMN_red PF03358.15 ABX13633.1 - 1e-24 87.0 0.0 1.3e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ABX13633.1 - 5.3e-09 36.1 0.0 7.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF2951 PF11166.8 ABX13633.1 - 0.12 12.6 0.9 0.7 10.1 0.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2951) UPF0242 PF06785.11 ABX13634.1 - 0.00013 22.2 1.1 0.00016 21.8 1.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Yuri_gagarin PF15934.5 ABX13634.1 - 0.00069 19.5 2.5 0.00077 19.4 2.5 1.1 1 0 0 1 1 1 1 Yuri gagarin Kei1 PF08552.11 ABX13634.1 - 0.0036 17.2 0.7 0.0043 16.9 0.7 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF3450 PF11932.8 ABX13634.1 - 0.0039 16.5 2.6 0.0051 16.2 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF2730 PF10805.8 ABX13634.1 - 0.0054 16.8 2.5 0.0054 16.8 2.5 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF2730) SPC25 PF06703.11 ABX13634.1 - 0.0096 15.7 0.5 0.013 15.3 0.5 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) YflT PF11181.8 ABX13634.1 - 0.011 16.2 1.5 0.016 15.7 1.5 1.2 1 0 0 1 1 1 0 Heat induced stress protein YflT SID-1_RNA_chan PF13965.6 ABX13634.1 - 0.015 13.8 1.0 0.017 13.6 1.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Fzo_mitofusin PF04799.13 ABX13634.1 - 0.049 13.2 6.0 0.065 12.8 6.0 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF641 PF04859.12 ABX13634.1 - 0.055 13.8 5.9 0.13 12.6 5.9 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Tnp_22_trimer PF17489.2 ABX13634.1 - 0.06 13.3 0.4 0.19 11.7 0.3 1.8 2 0 0 2 2 2 0 L1 transposable element trimerization domain ATG16 PF08614.11 ABX13634.1 - 0.086 13.1 10.7 0.1 12.8 10.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Cluap1 PF10234.9 ABX13634.1 - 0.088 12.2 7.2 0.11 11.9 7.2 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 MLANA PF14991.6 ABX13634.1 - 0.11 12.7 0.2 0.18 12.1 0.2 1.5 1 1 0 1 1 1 0 Protein melan-A HrpB7 PF09486.10 ABX13634.1 - 0.18 12.2 1.3 0.4 11.1 1.3 1.5 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 ABX13634.1 - 0.3 11.1 5.0 0.44 10.6 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SPG4 PF17325.2 ABX13634.1 - 0.34 12.0 3.9 0.5 11.5 3.9 1.1 1 0 0 1 1 1 0 Stationary phase protein 4 FlaC_arch PF05377.11 ABX13634.1 - 0.34 11.3 8.3 1.6 9.1 1.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YbbR PF07949.12 ABX13634.1 - 0.35 11.2 3.1 0.73 10.2 2.9 1.6 1 1 0 1 1 1 0 YbbR-like protein CheY-binding PF09078.11 ABX13634.1 - 0.47 10.6 5.0 2.5 8.3 0.6 3.1 1 1 2 3 3 3 0 CheY binding Fib_alpha PF08702.10 ABX13634.1 - 0.6 10.3 9.4 0.92 9.7 9.4 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Med9 PF07544.13 ABX13634.1 - 0.81 9.8 7.4 1.2 9.3 6.3 1.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Peptidase_U4 PF03419.13 ABX13634.1 - 1.1 8.5 4.6 1.1 8.5 0.4 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DUF1192 PF06698.11 ABX13634.1 - 1.6 8.8 4.0 3.3 7.9 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DivIC PF04977.15 ABX13634.1 - 2.3 8.1 10.2 13 5.6 2.4 2.9 1 1 2 3 3 3 0 Septum formation initiator FAM76 PF16046.5 ABX13634.1 - 4.2 6.6 12.8 8 5.7 12.8 1.5 1 1 0 1 1 1 0 FAM76 protein HTH_23 PF13384.6 ABX13635.1 - 0.0067 16.2 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.10 ABX13635.1 - 0.02 14.7 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain CC190 PF15768.5 ABX13635.1 - 0.028 14.5 0.1 0.029 14.4 0.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 DUF5388 PF17363.2 ABX13635.1 - 0.061 13.5 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5388) GntR PF00392.21 ABX13635.1 - 0.092 12.4 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family Pro_isomerase PF00160.21 ABX13636.1 - 9.3e-52 175.5 0.1 1e-51 175.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AHJR-like PF18743.1 ABX13639.1 - 0.036 13.6 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 REase_AHJR-like DUF4695 PF15766.5 ABX13639.1 - 0.084 13.1 0.2 0.14 12.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) DUF3712 PF12505.8 ABX13640.1 - 0.087 13.1 0.2 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3712) PfkB PF00294.24 ABX13641.1 - 1.5e-25 90.1 0.1 2.3e-25 89.5 0.1 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ABX13641.1 - 7.8e-05 22.2 0.1 0.00017 21.0 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 ABX13641.1 - 0.00044 19.8 0.1 0.33 10.4 0.1 2.4 2 1 0 2 2 2 2 Carbohydrate kinase dUTPase_2 PF08761.11 ABX13642.1 - 7.2e-19 68.6 6.2 8.8e-14 52.0 0.3 2.0 1 1 1 2 2 2 2 dUTPase PRA-PH PF01503.17 ABX13642.1 - 0.00046 20.6 0.0 0.0006 20.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MtrA PF04208.14 ABX13643.1 - 3.4e-27 95.2 0.0 4.2e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit A FAINT PF04385.15 ABX13643.1 - 0.019 15.0 0.5 0.041 13.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function, DUF529 DegT_DnrJ_EryC1 PF01041.17 ABX13644.1 - 5.6e-114 381.2 0.0 6.3e-114 381.0 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ABX13644.1 - 6.8e-10 38.4 0.3 1e-09 37.9 0.3 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ABX13644.1 - 2.5e-09 36.8 0.0 4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ABX13644.1 - 1e-06 27.5 0.6 2.1e-06 26.6 0.6 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 ABX13644.1 - 0.00022 20.6 0.0 0.00092 18.6 0.0 2.1 1 1 0 1 1 1 1 Beta-eliminating lyase ComK PF06338.11 ABX13644.1 - 0.0074 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 ComK protein PseudoU_synth_2 PF00849.22 ABX13644.1 - 0.077 13.1 0.0 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 RNA pseudouridylate synthase DHQ_synthase PF01761.20 ABX13646.1 - 0.023 13.9 0.1 0.027 13.7 0.1 1.0 1 0 0 1 1 1 0 3-dehydroquinate synthase ACP_PD PF04336.12 ABX13646.1 - 0.023 15.1 0.0 0.025 15.0 0.0 1.0 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase tRNA-synt_1b PF00579.25 ABX13647.1 - 5.5e-41 140.8 0.3 7.1e-41 140.4 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TP_methylase PF00590.20 ABX13648.1 - 4.3e-37 128.1 0.0 5.2e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF1522 PF07482.11 ABX13648.1 - 0.14 12.5 0.1 0.49 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) RVT_3 PF13456.6 ABX13649.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like PD40 PF07676.12 ABX13649.1 - 0.03 14.3 3.8 8.2 6.5 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat NTP_transferase PF00483.23 ABX13649.1 - 0.095 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase AA_kinase PF00696.28 ABX13650.1 - 1.1e-52 179.0 0.6 1.1e-52 179.0 0.6 1.7 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.6 ABX13650.1 - 7.5e-20 70.5 3.8 1.5e-11 43.9 0.3 2.7 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 ABX13650.1 - 1.6e-17 62.9 0.4 2.4e-09 36.8 0.0 2.6 2 0 0 2 2 2 2 ACT domain PEX11 PF05648.14 ABX13650.1 - 0.0076 15.7 0.6 0.013 15.0 0.6 1.3 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ACT_6 PF13740.6 ABX13650.1 - 0.048 13.7 0.6 0.54 10.3 0.1 2.8 3 0 0 3 3 3 0 ACT domain Phasin PF05597.11 ABX13650.1 - 0.38 10.8 3.7 3.4 7.7 0.7 3.1 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PCNA_N PF00705.18 ABX13651.1 - 2.2e-19 69.4 0.0 4.4e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 ABX13651.1 - 3e-16 59.8 0.6 1.1e-14 54.7 0.0 2.7 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 ABX13651.1 - 8.1e-08 31.6 0.0 0.00042 19.5 0.0 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 ABX13651.1 - 0.053 13.0 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Rad9 Receptor_2B4 PF11465.8 ABX13651.1 - 0.058 13.6 0.1 0.13 12.4 0.1 1.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 TFIIS_C PF01096.18 ABX13652.1 - 4.6e-20 71.2 6.8 4.6e-20 71.2 6.8 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ABX13652.1 - 4.8e-06 26.3 13.8 0.005 16.7 6.3 4.0 3 1 0 3 3 3 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 ABX13652.1 - 0.00036 20.5 10.6 0.011 15.8 2.0 2.5 2 1 0 2 2 2 2 Double zinc ribbon zinc_ribbon_4 PF13717.6 ABX13652.1 - 0.0017 18.3 15.5 0.37 10.8 0.4 4.0 3 1 0 3 3 3 2 zinc-ribbon domain Elf1 PF05129.13 ABX13652.1 - 0.0044 17.0 4.6 0.56 10.3 0.1 2.3 2 0 0 2 2 2 2 Transcription elongation factor Elf1 like UPF0547 PF10571.9 ABX13652.1 - 0.057 13.5 14.0 0.69 10.1 4.6 3.7 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.10 ABX13652.1 - 0.06 13.5 11.2 4.1 7.6 0.0 4.1 4 0 0 4 4 4 0 Zinc ribbon domain Baculo_LEF5_C PF11792.8 ABX13652.1 - 0.068 12.9 1.1 0.068 12.9 1.1 3.3 3 1 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain C1_1 PF00130.22 ABX13652.1 - 0.08 12.8 12.7 0.13 12.1 2.5 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.6 ABX13652.1 - 0.15 11.8 17.6 6.4 6.6 7.7 4.0 3 1 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 ABX13652.1 - 0.2 11.9 13.3 0.77 10.0 2.5 3.2 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain Ribosomal_L44 PF00935.19 ABX13652.1 - 0.3 11.6 8.9 7.6 7.1 1.9 3.3 3 1 0 3 3 3 0 Ribosomal protein L44 OrfB_Zn_ribbon PF07282.11 ABX13652.1 - 0.35 10.8 14.3 0.31 11.0 1.9 3.0 1 1 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 ABX13652.1 - 0.36 10.8 14.7 3.8 7.6 4.3 3.0 2 2 0 2 2 2 0 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.12 ABX13652.1 - 0.38 10.8 13.4 3.6e+02 1.2 13.4 2.8 1 1 0 1 1 1 0 zinc-ribbons zf-Mss51 PF13824.6 ABX13652.1 - 0.43 10.7 12.7 0.25 11.5 1.7 3.0 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2387 PF09526.10 ABX13652.1 - 0.71 10.1 18.5 1.7 8.8 6.3 3.7 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Cytochrom_CIII PF02085.16 ABX13652.1 - 1 9.7 9.0 4.4 7.7 5.2 2.2 1 1 1 2 2 2 0 Class III cytochrome C family TackOD1 PF18551.1 ABX13652.1 - 1.3 8.7 10.6 12 5.6 10.6 2.4 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 Nudix_N_2 PF14803.6 ABX13652.1 - 1.4 8.9 12.3 18 5.4 0.4 4.0 3 1 0 3 3 3 0 Nudix N-terminal zf-ribbon_3 PF13248.6 ABX13652.1 - 1.8 8.1 13.6 3.1 7.3 0.2 3.9 4 0 0 4 4 4 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 ABX13652.1 - 3.3 7.5 16.4 13 5.6 4.6 4.0 3 1 0 3 3 3 0 A2L zinc ribbon domain zf-NADH-PPase PF09297.11 ABX13652.1 - 6.4 6.5 12.4 3.2 7.5 3.1 3.5 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 ABX13652.1 - 7.2 6.7 12.9 1.2e+03 -0.5 13.0 2.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3795 PF12675.7 ABX13652.1 - 7.5 7.1 13.4 1.1 9.8 8.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) zinc_ribbon_15 PF17032.5 ABX13652.1 - 8 7.3 17.6 9.6e+02 0.6 17.6 2.9 1 1 0 1 1 1 0 zinc-ribbon family zf-TFIIB PF13453.6 ABX13652.1 - 9.8 5.6 10.4 4.8 6.6 2.2 3.2 3 1 0 3 3 3 0 Transcription factor zinc-finger C1_2 PF03107.16 ABX13652.1 - 9.8 6.6 14.8 24 5.3 1.8 3.0 2 1 0 2 2 2 0 C1 domain RNA_pol_L_2 PF13656.6 ABX13653.1 - 1.5e-13 50.3 0.1 1.8e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DSPc PF00782.20 ABX13656.1 - 5.9e-17 61.7 0.0 7.9e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ABX13656.1 - 7e-09 35.6 0.1 2.7e-08 33.7 0.0 1.7 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ABX13656.1 - 4.7e-08 33.3 0.0 6.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 ABX13656.1 - 0.001 18.7 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 ABX13656.1 - 0.0037 17.3 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 ABX13656.1 - 0.0068 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family GDH_N PF12466.8 ABX13656.1 - 0.027 14.7 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal UDPG_MGDP_dh_N PF03721.14 ABX13656.1 - 0.1 12.2 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cyclase PF04199.13 ABX13657.1 - 4e-32 111.3 0.0 5.1e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase AsnC_trans_reg PF01037.21 ABX13658.1 - 2.5e-07 30.6 0.4 2.6e-07 30.5 0.4 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain phage_tail_N PF08400.10 ABX13658.1 - 0.055 13.5 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Aminotran_5 PF00266.19 ABX13659.1 - 5.5e-66 223.0 0.0 6.5e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ABX13659.1 - 4.1e-09 36.1 0.0 6.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ABX13659.1 - 0.022 14.1 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase SEO_C PF14577.6 ABX13660.1 - 0.031 13.7 0.3 0.043 13.2 0.3 1.3 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Elong_Iki1 PF10483.9 ABX13660.1 - 0.071 12.6 0.1 0.089 12.3 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 Fer4 PF00037.27 ABX13661.1 - 2e-11 43.2 10.6 5.1e-07 29.3 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 ABX13661.1 - 6.9e-09 36.2 3.7 9.8e-09 35.7 3.7 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABX13661.1 - 3.5e-08 33.2 8.1 0.0013 18.7 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 ABX13661.1 - 4.5e-08 33.1 1.8 6.4e-08 32.6 1.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 ABX13661.1 - 4.4e-06 26.8 4.1 1.8e-05 24.8 4.2 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 ABX13661.1 - 1.5e-05 24.8 7.8 0.018 15.1 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 ABX13661.1 - 7.5e-05 23.2 4.2 0.12 12.9 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_10 PF13237.6 ABX13661.1 - 0.00016 21.7 8.4 0.0055 16.8 9.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 ABX13661.1 - 0.00025 21.3 6.9 0.081 13.5 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 ABX13661.1 - 0.00027 21.8 5.4 0.076 14.0 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 ABX13661.1 - 0.00094 20.0 2.9 0.3 12.0 0.9 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 ABX13661.1 - 0.0013 19.5 11.2 0.097 13.7 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 ABX13661.1 - 0.0052 17.2 5.8 0.048 14.1 5.8 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 ABX13661.1 - 0.027 15.0 6.5 0.89 10.1 6.6 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 ABX13661.1 - 0.077 13.7 10.7 0.51 11.1 2.1 2.9 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 ABX13661.1 - 0.7 10.1 10.3 1.8 8.8 3.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Guanylate_cyc PF00211.20 ABX13662.1 - 2.9e-15 56.4 0.1 5.1e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HAMP PF00672.25 ABX13662.1 - 5.5e-13 49.1 0.1 1e-12 48.2 0.1 1.5 1 0 0 1 1 1 1 HAMP domain dCache_1 PF02743.18 ABX13662.1 - 3.3e-09 36.9 0.1 6.5e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Cache domain DnaJ PF00226.31 ABX13663.1 - 6.5e-11 42.2 0.0 1.5e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain CooT PF10133.9 ABX13663.1 - 0.21 11.9 1.7 1.1 9.6 0.1 2.9 2 1 1 3 3 3 0 CO dehydrogenase accessory protein CooT Usp PF00582.26 ABX13664.1 - 2.2e-30 106.0 0.0 2.6e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF3880 PF12996.7 ABX13664.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) AA_permease_2 PF13520.6 ABX13665.1 - 6.6e-46 157.0 59.1 8.6e-46 156.6 59.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABX13665.1 - 2.2e-41 142.0 50.4 3.3e-41 141.4 50.4 1.3 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 ABX13665.1 - 6.3e-09 35.1 26.3 6.3e-09 35.1 26.3 2.8 1 1 1 3 3 3 1 Spore germination protein AA_permease_C PF13906.6 ABX13665.1 - 0.06 13.4 0.6 0.06 13.4 0.6 4.5 5 1 0 5 5 5 0 C-terminus of AA_permease Gln-synt_C PF00120.24 ABX13667.1 - 2.3e-116 388.6 0.0 3.1e-116 388.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ABX13667.1 - 1.5e-23 82.3 0.1 2.8e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Fer4_14 PF13394.6 ABX13668.1 - 3.6e-05 23.9 0.0 9.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 ABX13668.1 - 0.00017 21.8 0.0 0.0003 21.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 ABX13668.1 - 0.001 19.5 0.0 0.0026 18.1 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily RVT_connect PF06815.13 ABX13668.1 - 0.012 15.9 0.1 0.59 10.4 0.0 2.6 2 1 0 2 2 2 0 Reverse transcriptase connection domain MS_channel PF00924.18 ABX13669.1 - 1.7e-29 102.8 0.3 3.1e-29 102.0 0.3 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Pribosyltran_N PF13793.6 ABX13670.1 - 8.2e-27 93.5 0.6 7.6e-25 87.1 0.0 2.2 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ABX13670.1 - 1.8e-17 63.3 0.6 3.7e-17 62.3 0.6 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 ABX13670.1 - 1.1e-12 48.4 5.9 4.3e-12 46.5 1.0 3.1 2 2 1 3 3 3 1 Phosphoribosyl synthetase-associated domain UPRTase PF14681.6 ABX13670.1 - 0.00036 20.0 0.0 0.00061 19.3 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 ABX13670.1 - 0.001 18.6 0.1 0.0024 17.4 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase Asp_Glu_race PF01177.22 ABX13670.1 - 0.0021 18.0 0.2 0.0035 17.2 0.2 1.3 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase SRI PF08236.11 ABX13670.1 - 2 8.6 9.2 4.5 7.5 0.1 3.2 3 0 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain UPF0020 PF01170.18 ABX13671.1 - 2e-22 79.8 0.2 1.9e-21 76.7 0.2 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 ABX13671.1 - 1.1e-11 44.7 0.0 2.4e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 ABX13671.1 - 3.9e-11 43.1 0.0 1.9e-10 40.9 0.0 2.1 2 1 0 2 2 2 1 DNA methylase Methyltransf_25 PF13649.6 ABX13671.1 - 2.2e-09 37.9 0.0 4.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ABX13671.1 - 1.9e-07 30.9 0.0 3.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 ABX13671.1 - 4.9e-06 26.2 0.0 9.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 ABX13671.1 - 2.3e-05 23.8 0.1 4.4e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ABX13671.1 - 3.2e-05 24.5 0.0 6.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 ABX13671.1 - 6.8e-05 22.3 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase PrmA PF06325.13 ABX13671.1 - 0.00011 21.7 0.0 0.00026 20.5 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 ABX13671.1 - 0.00021 20.7 0.0 0.00041 19.7 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase AviRa PF11599.8 ABX13671.1 - 0.00029 20.4 0.1 0.21 11.0 0.0 2.3 1 1 1 2 2 2 2 RRNA methyltransferase AviRa Methyltransf_5 PF01795.19 ABX13671.1 - 0.00036 20.1 0.0 0.00072 19.2 0.0 1.4 1 0 0 1 1 1 1 MraW methylase family MethyltransfD12 PF02086.15 ABX13671.1 - 0.00075 19.3 0.1 0.0018 18.0 0.0 1.8 1 1 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_15 PF09445.10 ABX13671.1 - 0.00097 18.8 0.2 0.074 12.6 0.0 2.4 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase THUMP PF02926.17 ABX13671.1 - 0.004 17.2 0.4 0.013 15.6 0.0 2.0 2 1 0 2 2 2 1 THUMP domain PCMT PF01135.19 ABX13671.1 - 0.0068 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF43 PF01861.16 ABX13671.1 - 0.012 14.9 0.0 0.029 13.6 0.0 1.6 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_23 PF13489.6 ABX13671.1 - 0.02 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S8e PF01201.22 ABX13671.1 - 0.044 13.9 0.2 1 9.5 0.0 2.5 2 1 0 2 2 2 0 Ribosomal protein S8e Met_10 PF02475.16 ABX13671.1 - 0.056 13.2 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.12 ABX13671.1 - 0.092 13.5 0.0 0.24 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Lactamase_B_2 PF12706.7 ABX13672.1 - 1.8e-15 57.0 0.0 2.6e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ABX13672.1 - 1.3e-07 31.8 0.0 6e-07 29.7 0.0 2.1 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 ABX13672.1 - 0.012 15.3 0.0 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 tRNase Z endonuclease NAD_binding_10 PF13460.6 ABX13672.1 - 0.074 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Cucumo_coat PF00760.18 ABX13672.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Cucumovirus coat protein SIR2 PF02146.17 ABX13673.1 - 3.4e-54 183.4 0.0 4.4e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 ABX13673.1 - 0.00032 20.4 0.0 0.052 13.3 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Sec34 PF04136.15 ABX13674.1 - 0.034 14.0 1.4 0.066 13.1 1.4 1.5 1 0 0 1 1 1 0 Sec34-like family Med2 PF11214.8 ABX13674.1 - 0.051 13.7 1.3 0.11 12.7 0.7 1.8 1 1 0 1 1 1 0 Mediator complex subunit 2 Phage_min_cap2 PF06152.11 ABX13674.1 - 0.38 9.6 2.7 1.1 8.0 2.7 1.7 1 1 0 1 1 1 0 Phage minor capsid protein 2 Spo0A_C PF08769.11 ABX13674.1 - 0.96 9.6 3.3 2.4 8.3 0.4 2.4 2 1 1 3 3 3 0 Sporulation initiation factor Spo0A C terminal RNA_binding PF01877.17 ABX13675.1 - 8.5e-12 45.4 0.2 1.5e-11 44.6 0.2 1.4 1 1 0 1 1 1 1 RNA binding AAA_17 PF13207.6 ABX13676.1 - 2.8e-14 53.7 0.1 3.6e-14 53.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ABX13676.1 - 1.2e-12 48.5 0.1 1.7e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ABX13676.1 - 2.7e-06 27.6 0.0 4.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ABX13676.1 - 0.0029 17.9 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ABX13676.1 - 0.0083 16.1 0.3 0.42 10.5 0.1 2.3 1 1 1 2 2 2 1 NTPase CoaE PF01121.20 ABX13676.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 Dephospho-CoA kinase APS_kinase PF01583.20 ABX13676.1 - 0.015 15.2 0.0 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase MeaB PF03308.16 ABX13676.1 - 0.017 14.1 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cytidylate_kin2 PF13189.6 ABX13676.1 - 0.019 15.1 0.1 7.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family Zeta_toxin PF06414.12 ABX13676.1 - 0.022 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 ABX13676.1 - 0.024 13.8 0.1 0.043 13.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 ABX13676.1 - 0.044 14.2 0.3 0.11 12.9 0.3 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABX13676.1 - 0.054 13.8 0.3 0.14 12.5 0.3 1.8 1 1 0 1 1 1 0 AAA domain ADK PF00406.22 ABX13676.1 - 0.065 13.3 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase KTI12 PF08433.10 ABX13676.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 ABX13676.1 - 0.088 12.6 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0180 PF03698.13 ABX13676.1 - 0.12 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) AAA_16 PF13191.6 ABX13676.1 - 0.12 12.7 0.2 0.21 12.0 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 ABX13676.1 - 0.13 12.7 2.5 0.29 11.6 2.5 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABX13676.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain LigT_PEase PF02834.16 ABX13677.1 - 1.3e-25 89.4 0.0 2e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.9 ABX13677.1 - 1.1e-14 54.8 0.3 1.6e-14 54.3 0.3 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 ABX13677.1 - 4.6e-10 39.6 0.0 5.8e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily YPEB PF14620.6 ABX13677.1 - 0.0064 15.9 0.2 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 YpeB sporulation tRNA_NucTransf2 PF09249.11 ABX13678.1 - 5e-38 129.8 0.1 1e-37 128.8 0.1 1.5 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain NTP_transf_2 PF01909.23 ABX13678.1 - 2e-10 40.8 0.5 6.4e-10 39.2 0.5 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ABX13678.1 - 0.00026 21.0 0.2 0.00077 19.5 0.2 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase SMODS PF18144.1 ABX13678.1 - 0.012 15.8 0.2 0.021 15.0 0.2 1.6 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain RIO1 PF01163.22 ABX13679.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 ABX13679.1 - 1.8e-05 24.3 1.6 1.8e-05 24.3 1.6 1.7 1 1 1 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 ABX13679.1 - 0.01 15.4 0.1 0.24 11.0 0.0 2.4 2 1 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 ABX13679.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family His_Me_b4a2 PF18275.1 ABX13680.1 - 0.00085 19.3 3.6 0.0016 18.5 3.6 1.7 1 1 0 1 1 1 1 His-Me finger endonuclease beta4-alpha2 domain Pyr_redox_2 PF07992.14 ABX13681.1 - 2.3e-25 89.5 0.0 5.6e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABX13681.1 - 3.9e-06 27.3 2.7 0.029 14.9 0.1 3.5 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABX13681.1 - 0.0035 17.5 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ABX13681.1 - 0.0037 17.3 0.0 0.075 13.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 ABX13681.1 - 0.015 14.9 0.0 0.041 13.5 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ABX13681.1 - 0.042 12.7 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 ABX13681.1 - 0.25 10.4 0.0 5.1 6.1 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain adh_short PF00106.25 ABX13682.1 - 2.9e-62 209.6 0.6 3.7e-62 209.3 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABX13682.1 - 1.1e-46 159.3 1.2 1.3e-46 159.1 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABX13682.1 - 8.9e-14 51.8 0.2 1.3e-13 51.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABX13682.1 - 0.00064 19.2 0.5 0.15 11.5 0.5 2.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ABX13682.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.15 ABX13682.1 - 0.027 14.3 0.2 0.069 13.0 0.2 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.8 ABX13682.1 - 0.15 11.8 1.2 0.35 10.6 1.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-AN1 PF01428.16 ABX13683.1 - 6.1e-12 45.5 8.1 8.2e-12 45.1 8.1 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger RecR PF02132.15 ABX13683.1 - 0.03 13.9 1.1 0.055 13.0 1.1 1.5 1 0 0 1 1 1 0 RecR protein PSI_integrin PF17205.3 ABX13683.1 - 0.06 13.1 5.9 4.6 7.1 5.9 2.2 1 1 0 1 1 1 0 Integrin plexin domain Transp_Tc5_C PF04236.15 ABX13683.1 - 0.15 12.4 4.8 0.38 11.1 4.8 1.7 1 1 0 1 1 1 0 Tc5 transposase C-terminal domain zf-C2H2_4 PF13894.6 ABX13683.1 - 1.6 9.8 7.2 0.68 10.9 2.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger CLN6 PF15156.6 ABX13684.1 - 0.004 16.5 0.4 0.0045 16.3 0.4 1.1 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 B12D PF06522.11 ABX13684.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Npun_R1517 PF18068.1 ABX13685.1 - 0.023 15.0 1.1 0.051 13.9 0.4 1.9 1 1 0 2 2 2 0 Npun R1517 Bac_DNA_binding PF00216.21 ABX13685.1 - 0.041 14.1 0.2 0.093 13.0 0.2 1.5 1 0 0 1 1 1 0 Bacterial DNA-binding protein Kin17_mid PF10357.9 ABX13685.1 - 0.077 12.9 2.3 1.6 8.7 0.3 2.4 1 1 1 2 2 2 0 Domain of Kin17 curved DNA-binding protein Ca_bind_SSO6904 PF18249.1 ABX13685.1 - 0.13 12.6 2.8 0.64 10.4 0.3 2.3 1 1 1 2 2 2 0 Calcium binding protein SSO6904 Gln-synt_C PF00120.24 ABX13686.1 - 1.9e-114 382.3 0.0 2.2e-114 382.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ABX13686.1 - 1.3e-26 92.2 0.0 2.6e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RseC_MucC PF04246.12 ABX13687.1 - 0.43 10.5 3.1 0.37 10.7 2.4 1.3 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Cpn60_TCP1 PF00118.24 ABX13688.1 - 7.2e-184 612.0 19.3 8.2e-184 611.8 19.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dak2 PF02734.17 ABX13688.1 - 0.0074 16.2 1.2 2.4 8.0 0.4 2.5 2 0 0 2 2 2 2 DAK2 domain SHMT PF00464.19 ABX13689.1 - 6.6e-76 255.5 0.1 8.3e-76 255.1 0.1 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 ABX13689.1 - 4e-08 32.8 0.1 1.8e-07 30.7 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ABX13689.1 - 1.3e-07 31.3 0.0 2.2e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ABX13689.1 - 7.2e-05 21.9 0.1 0.00012 21.2 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class-V SelA PF03841.13 ABX13689.1 - 0.0027 16.8 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Myb_DNA-bind_3 PF12776.7 ABX13689.1 - 0.53 11.3 0.1 0.53 11.3 0.1 2.1 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain PolC_DP2 PF03833.13 ABX13690.1 - 0 1060.7 0.0 0 1060.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.12 ABX13690.1 - 0.36 10.9 13.2 2.6 8.1 9.4 2.6 2 0 0 2 2 2 0 zinc-ribbons HypA PF01155.19 ABX13690.1 - 8.2 6.5 11.0 6 6.9 4.3 3.4 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PcrB PF01884.17 ABX13691.1 - 2.3e-53 181.0 0.1 2.9e-53 180.6 0.1 1.0 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.21 ABX13691.1 - 5.8e-08 32.5 0.2 6.3e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein IMPDH PF00478.25 ABX13691.1 - 1.2e-07 31.0 0.0 1.6e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain B12-binding PF02310.19 ABX13691.1 - 0.00036 20.6 0.4 1 9.4 0.0 3.4 3 1 1 4 4 4 1 B12 binding domain Dus PF01207.17 ABX13691.1 - 0.0058 15.8 0.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 ABX13691.1 - 0.0077 15.6 0.1 0.068 12.5 0.0 2.1 2 0 0 2 2 2 1 Thiamine monophosphate synthase Ribul_P_3_epim PF00834.19 ABX13691.1 - 0.009 15.4 0.2 0.033 13.6 0.1 1.8 2 0 0 2 2 2 1 Ribulose-phosphate 3 epimerase family Trp_syntA PF00290.20 ABX13691.1 - 0.011 14.6 1.1 0.085 11.7 0.1 2.4 2 1 1 3 3 3 0 Tryptophan synthase alpha chain DHO_dh PF01180.21 ABX13691.1 - 0.018 14.2 1.2 0.029 13.6 0.2 1.7 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase ThiG PF05690.14 ABX13691.1 - 0.022 14.1 0.5 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG NanE PF04131.14 ABX13691.1 - 0.023 13.9 1.9 0.9 8.7 0.1 2.5 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 ABX13691.1 - 0.044 12.9 0.3 0.61 9.2 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase DpaA_N PF16924.5 ABX13691.1 - 0.048 13.7 0.6 0.41 10.8 0.1 2.2 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain FMN_dh PF01070.18 ABX13691.1 - 0.068 12.2 0.0 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 FMN-dependent dehydrogenase G3P_antiterm PF04309.12 ABX13691.1 - 0.12 11.8 1.5 0.32 10.4 0.1 2.2 2 1 1 3 3 3 0 Glycerol-3-phosphate responsive antiterminator PA PF02225.22 ABX13691.1 - 0.3 11.1 2.0 24 5.0 0.1 2.6 2 1 0 3 3 3 0 PA domain HTH_27 PF13463.6 ABX13693.1 - 1.4e-06 28.7 0.1 2.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 ABX13693.1 - 0.00011 22.0 0.5 0.00025 20.8 0.1 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Replic_Relax PF13814.6 ABX13693.1 - 0.0035 17.4 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 Replication-relaxation Ribosomal_L27e PF01777.18 ABX13693.1 - 0.0037 17.6 0.8 0.0037 17.6 0.8 2.2 2 1 1 3 3 3 1 Ribosomal L27e protein family HTH_Crp_2 PF13545.6 ABX13693.1 - 0.023 14.6 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 ABX13693.1 - 0.027 14.4 0.2 0.086 12.8 0.2 1.8 1 0 0 1 1 1 0 MarR family HTH_45 PF14947.6 ABX13693.1 - 0.028 14.4 1.2 0.092 12.7 0.3 2.2 2 1 0 2 2 2 0 Winged helix-turn-helix DUF1495 PF07381.11 ABX13693.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) Rrf2 PF02082.20 ABX13693.1 - 0.078 13.3 1.4 0.58 10.6 0.1 2.4 2 1 0 2 2 2 0 Transcriptional regulator MazE_antitoxin PF04014.18 ABX13694.1 - 2.9e-07 30.3 0.1 3.5e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin Rubredoxin_C PF18267.1 ABX13694.1 - 0.0056 16.6 0.1 0.0075 16.2 0.1 1.1 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain eIF-1a PF01176.19 ABX13694.1 - 0.081 12.7 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Translation initiation factor 1A / IF-1 Penicillinase_R PF03965.16 ABX13695.1 - 0.00074 19.9 0.0 0.001 19.4 0.0 1.2 1 0 0 1 1 1 1 Penicillinase repressor HTH_ABP1_N PF18107.1 ABX13695.1 - 0.1 12.3 0.5 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Nitrosopumilus_maritimus_SCM1-ASM1846v1/GCA_000018465.1_ASM1846v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Nitrosopumilus_maritimus_SCM1-ASM1846v1/GCA_000018465.1_ASM1846v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Nitrosopumilus_maritimus_SCM1-ASM1846v1/GCA_000018465.1_ASM1846v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Nitrosopumilus_maritimus_SCM1-ASM1846v1/GCA_000018465.1_ASM1846v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 16:21:15 2019 # [ok]