# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DNA_RNApol_7kD PF03604.13 AJA91819.1 - 7e-06 25.6 4.0 1.4e-05 24.6 4.0 1.5 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit TFIIS_C PF01096.18 AJA91819.1 - 0.07 13.0 0.4 0.07 13.0 0.4 1.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Lactococcin_972 PF09683.10 AJA91820.1 - 1 10.0 9.6 3.9 8.1 9.5 1.9 1 1 0 1 1 1 0 Bacteriocin (Lactococcin_972) DDRGK PF09756.9 AJA91820.1 - 6.7 6.3 23.9 8.1 6.0 23.9 1.1 1 0 0 1 1 1 0 DDRGK domain Lactamase_B_3 PF13483.6 AJA91821.1 - 3.2e-12 46.6 0.0 6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 AJA91821.1 - 0.00065 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AJA91821.1 - 0.018 15.0 0.1 0.031 14.3 0.1 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Sdh5 PF03937.16 AJA91821.1 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Glu-tRNAGln PF02686.15 AJA91822.1 - 0.00051 20.3 0.1 0.00081 19.6 0.1 1.5 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Peptidase_C23 PF05379.11 AJA91822.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Carlavirus endopeptidase MerC PF03203.14 AJA91824.1 - 0.058 13.8 1.5 0.064 13.7 1.5 1.0 1 0 0 1 1 1 0 MerC mercury resistance protein NifU_N PF01592.16 AJA91825.1 - 2.9e-26 92.1 0.0 3.5e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain SufE PF02657.15 AJA91825.1 - 0.0022 17.8 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Fe-S metabolism associated domain NTP_transferase PF00483.23 AJA91826.1 - 2.8e-56 190.9 0.0 3.7e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 AJA91826.1 - 1.2e-09 37.5 21.0 4.9e-06 26.1 6.7 3.9 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 AJA91826.1 - 2.7e-09 37.6 0.0 3.5e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 AJA91826.1 - 0.0056 16.4 13.1 0.0064 16.2 5.8 3.1 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 AJA91826.1 - 0.25 10.2 1.4 0.43 9.5 1.4 1.3 1 0 0 1 1 1 0 L-fucokinase Cpn60_TCP1 PF00118.24 AJA91827.1 - 1.8e-178 594.2 22.1 2.1e-178 594.0 22.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dak2 PF02734.17 AJA91827.1 - 4.5e-05 23.4 1.3 0.33 10.8 0.0 2.9 3 0 0 3 3 3 2 DAK2 domain UDG PF03167.19 AJA91828.1 - 1e-43 149.0 0.0 1.3e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Epimerase_2 PF02350.19 AJA91828.1 - 0.0005 19.0 0.0 0.00072 18.5 0.0 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF1053 PF06327.14 AJA91828.1 - 0.058 14.0 0.6 0.35 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) IDH PF03971.14 AJA91828.1 - 0.12 10.8 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase Fer4_9 PF13187.6 AJA91828.1 - 0.81 9.9 6.2 4.5 7.5 1.8 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain SBP_bac_5 PF00496.22 AJA91829.1 - 6e-26 91.3 11.7 9.9e-22 77.4 0.0 2.8 2 1 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 5 Middle SMC_ScpA PF02616.14 AJA91831.1 - 1.7e-07 31.5 2.6 0.00094 19.2 0.1 2.2 2 0 0 2 2 2 2 Segregation and condensation protein ScpA DUF2582 PF10771.9 AJA91831.1 - 0.011 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) CNDH2_C PF16858.5 AJA91831.1 - 0.014 15.2 0.1 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RuvX PF03652.15 AJA91832.1 - 0.00089 19.6 0.1 0.036 14.5 0.1 2.3 1 1 0 1 1 1 1 Holliday junction resolvase DUF460 PF04312.13 AJA91832.1 - 0.0037 17.0 0.1 0.0078 15.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF460) T2SSS_2 PF16549.5 AJA91832.1 - 0.085 12.9 0.1 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS) pilotin, S protein UPF0182 PF03699.13 AJA91833.1 - 3.6e-38 131.2 12.3 2.2e-37 128.7 12.3 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0182) RGS_DHEX PF18148.1 AJA91835.1 - 0.075 13.2 0.3 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain TMEM171 PF15471.6 AJA91835.1 - 1.2 8.1 2.8 1.8 7.5 2.8 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF3408 PF11888.8 AJA91835.1 - 1.4 9.0 6.6 0.98 9.6 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3408) UPF0052 PF01933.18 AJA91836.1 - 8.5e-55 186.1 0.0 1e-54 185.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Flavodoxin_1 PF00258.25 AJA91837.1 - 7.6e-22 78.1 0.0 8.9e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin ANAPC5 PF12862.7 AJA91837.1 - 0.074 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 RuvX PF03652.15 AJA91837.1 - 0.16 12.3 0.0 2 8.8 0.0 2.1 2 0 0 2 2 2 0 Holliday junction resolvase AAA PF00004.29 AJA91838.1 - 1.2e-38 132.5 0.0 3.3e-38 131.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AJA91838.1 - 5.9e-07 29.7 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 AJA91838.1 - 7e-07 29.2 0.0 2.5e-06 27.4 0.0 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 AJA91838.1 - 7e-06 26.4 0.1 0.0014 18.9 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 AJA91838.1 - 8.4e-06 26.3 0.0 0.0036 17.7 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 AJA91838.1 - 2.8e-05 23.8 0.0 8.7e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain MIT PF04212.18 AJA91838.1 - 3e-05 24.0 4.6 5.8e-05 23.1 4.6 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_5 PF07728.14 AJA91838.1 - 6.6e-05 22.9 0.1 0.0024 17.8 0.1 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AJA91838.1 - 6.8e-05 22.7 0.0 0.00033 20.4 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 AJA91838.1 - 0.00013 22.1 0.2 0.004 17.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 AJA91838.1 - 0.0019 17.8 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 AJA91838.1 - 0.0022 18.0 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AJA91838.1 - 0.004 16.9 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AJA91838.1 - 0.0043 17.0 0.0 3.3 7.6 0.0 2.6 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 AJA91838.1 - 0.0046 16.4 0.1 0.0098 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 AJA91838.1 - 0.0086 15.8 0.2 0.71 9.6 0.1 3.2 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.6 AJA91838.1 - 0.011 15.3 0.1 0.062 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 AJA91838.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 AJA91838.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 AJA91838.1 - 0.03 14.3 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain KAP_NTPase PF07693.14 AJA91838.1 - 0.04 13.1 0.0 0.17 11.1 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain AAA_11 PF13086.6 AJA91838.1 - 0.052 13.3 0.2 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain HTH_Tnp_Tc3_2 PF01498.18 AJA91838.1 - 0.061 13.6 0.1 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 Transposase RNA_helicase PF00910.22 AJA91838.1 - 0.062 13.7 0.1 0.37 11.2 0.0 2.3 2 1 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 AJA91838.1 - 0.076 12.2 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 AJA91838.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 AJA91838.1 - 0.11 11.7 0.0 0.61 9.3 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin ATPase PF06745.13 AJA91838.1 - 0.12 11.7 0.1 1.5 8.1 0.1 2.3 1 1 1 2 2 2 0 KaiC Tn7_Tnp_TnsA_C PF08721.11 AJA91838.1 - 0.15 12.7 0.1 3.7 8.3 0.0 2.8 3 0 0 3 3 3 0 TnsA endonuclease C terminal Zn_Tnp_IS1595 PF12760.7 AJA91839.1 - 0.067 13.2 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF4572 PF15139.6 AJA91839.1 - 0.12 12.2 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) HTH_20 PF12840.7 AJA91840.1 - 7.6e-10 38.7 0.6 2.1e-09 37.3 0.3 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 AJA91840.1 - 2.2e-06 27.4 1.0 2.2e-05 24.3 0.5 2.5 2 1 0 2 2 2 1 Bacterial regulatory protein, arsR family FUR PF01475.19 AJA91840.1 - 0.00029 21.0 2.1 0.0006 20.0 1.9 1.7 1 1 0 1 1 1 1 Ferric uptake regulator family AbiH PF14253.6 AJA91840.1 - 0.014 15.3 1.3 0.016 15.1 1.3 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH eIF3_N PF09440.10 AJA91840.1 - 0.022 15.2 6.6 0.023 15.1 1.1 2.1 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain DUF2240 PF09999.9 AJA91840.1 - 0.037 13.6 0.2 0.056 13.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) DUF4485 PF14846.6 AJA91840.1 - 0.048 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) SEA PF01390.20 AJA91840.1 - 0.061 13.4 0.5 0.13 12.3 0.5 1.7 1 0 0 1 1 1 0 SEA domain HTH_12 PF08461.10 AJA91840.1 - 0.067 13.2 0.4 0.2 11.7 0.4 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain ABC2_membrane_3 PF12698.7 AJA91840.1 - 0.16 11.0 1.1 0.18 10.9 1.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Lactamase_B_2 PF12706.7 AJA91841.1 - 2.9e-17 62.9 0.0 3.5e-08 33.2 0.0 2.1 1 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AJA91841.1 - 1.9e-08 34.6 0.0 1.1e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 AJA91841.1 - 6.9e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease DUF4130 PF13566.6 AJA91841.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 DUF4013 PF13197.6 AJA91842.1 - 0.0071 16.2 5.6 0.012 15.5 5.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4013) CPP1-like PF11833.8 AJA91842.1 - 0.011 15.4 0.2 0.014 15.1 0.2 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3397 PF11877.8 AJA91842.1 - 0.048 13.9 2.8 0.062 13.5 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) YrhC PF14143.6 AJA91842.1 - 1.2 9.3 3.8 7.7 6.7 2.0 2.0 1 1 1 2 2 2 0 YrhC-like protein PrgI PF12666.7 AJA91842.1 - 1.2 9.8 5.5 0.6 10.9 1.4 1.9 1 1 1 2 2 2 0 PrgI family protein Trm112p PF03966.16 AJA91843.1 - 6.4e-08 33.1 2.5 6.4e-08 33.1 2.5 1.8 2 1 0 2 2 2 1 Trm112p-like protein Elf1 PF05129.13 AJA91843.1 - 0.006 16.6 0.1 0.006 16.6 0.1 1.4 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like zf-RRPl_C4 PF17026.5 AJA91843.1 - 0.025 14.7 1.9 0.12 12.5 1.9 2.0 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Lar_restr_allev PF14354.6 AJA91843.1 - 0.086 13.2 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-C2H2_jaz PF12171.8 AJA91843.1 - 1.2 9.6 5.4 1.3 9.4 0.7 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HTH_3 PF01381.22 AJA91845.1 - 3.2e-05 23.9 0.2 0.00029 20.9 0.1 2.2 1 1 1 2 2 2 1 Helix-turn-helix Cro PF09048.10 AJA91845.1 - 0.042 13.9 0.0 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Cro HTH_19 PF12844.7 AJA91845.1 - 0.051 13.6 0.1 0.2 11.7 0.1 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AJA91845.1 - 0.059 13.2 0.0 0.35 10.8 0.0 2.3 2 1 1 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF2570 PF10828.8 AJA91845.1 - 0.077 12.8 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Fe_dep_repress PF01325.19 AJA91845.1 - 0.082 13.1 0.3 3.8 7.8 0.0 2.8 2 1 1 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain UPF0154 PF03672.13 AJA91845.1 - 0.1 12.6 0.5 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) F420_ligase PF01996.16 AJA91846.1 - 2.3e-55 187.6 1.9 2.9e-55 187.3 1.9 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase HpcH_HpaI PF03328.14 AJA91847.1 - 8e-46 155.9 0.0 9.5e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AJA91847.1 - 1e-12 47.9 0.5 3.4e-06 26.4 0.1 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 AJA91847.1 - 0.0048 15.8 0.7 0.008 15.1 0.7 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Exog_C PF18026.1 AJA91847.1 - 0.0083 16.2 1.4 0.24 11.5 0.7 2.8 2 0 0 2 2 2 1 Endo/exonuclease (EXOG) C-terminal domain Proteasome PF00227.26 AJA91848.1 - 1.4e-53 181.2 0.1 1.6e-53 181.0 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit DNA_methylase PF00145.17 AJA91849.1 - 7.3e-59 199.8 0.1 1.2e-58 199.1 0.1 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF3892 PF13031.6 AJA91851.1 - 9.1e-07 29.4 0.3 1.1e-06 29.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3892) ASCH PF04266.14 AJA91851.1 - 0.044 14.4 1.2 2.2 8.9 0.5 2.2 1 1 1 2 2 2 0 ASCH domain 2OG-FeII_Oxy_3 PF13640.6 AJA91852.1 - 1.2e-09 38.9 0.0 1.8e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 AJA91852.1 - 6.6e-06 26.5 0.0 1.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_4 PF13661.6 AJA91852.1 - 0.093 13.4 0.0 0.23 12.1 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NAD_binding_2 PF03446.15 AJA91853.1 - 1.5e-40 138.9 1.5 2.6e-40 138.2 1.5 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AJA91853.1 - 1.6e-20 73.5 0.1 3e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AJA91853.1 - 4.3e-08 33.6 0.2 1.2e-07 32.1 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AJA91853.1 - 1.7e-06 27.5 0.2 2.7e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 AJA91853.1 - 5.9e-06 26.4 0.2 1e-05 25.6 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 AJA91853.1 - 1.1e-05 25.1 0.2 2.1e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 AJA91853.1 - 0.0002 21.0 0.1 0.00034 20.3 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 AJA91853.1 - 0.0004 20.3 0.1 0.0012 18.7 0.1 1.8 1 1 1 2 2 2 1 Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 AJA91853.1 - 0.00073 19.6 0.2 0.017 15.1 0.2 2.4 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 AJA91853.1 - 0.0041 16.7 1.2 0.058 13.0 0.4 2.4 1 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 AJA91853.1 - 0.0045 16.9 2.2 0.0085 16.0 0.4 2.4 3 1 1 4 4 4 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 AJA91853.1 - 0.027 14.0 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 AJA91853.1 - 0.042 13.7 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding TrkA_N PF02254.18 AJA91853.1 - 0.058 13.6 0.2 0.17 12.2 0.2 1.9 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 AJA91853.1 - 0.083 13.3 0.3 0.16 12.4 0.3 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding GNAT_acetyltran PF12746.7 AJA91855.1 - 0.06 12.9 0.1 0.087 12.4 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase AraC_binding PF02311.19 AJA91855.1 - 0.091 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain HlyD_D23 PF16576.5 AJA91855.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Rib_5-P_isom_A PF06026.14 AJA91856.1 - 8.4e-52 175.3 0.1 1e-51 175.0 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 AJA91856.1 - 1.3e-05 25.2 0.2 0.017 15.1 0.1 2.8 2 1 0 3 3 3 2 DeoR C terminal sensor domain DUF4147 PF13660.6 AJA91856.1 - 0.035 13.6 0.2 0.048 13.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Tubulin PF00091.25 AJA91858.1 - 2.4e-16 60.5 3.9 6.6e-15 55.8 0.5 2.7 2 1 1 3 3 3 2 Tubulin/FtsZ family, GTPase domain Copper-bind PF00127.20 AJA91859.1 - 4.6e-08 33.4 0.1 0.016 15.7 0.0 4.0 4 2 0 4 4 4 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJA91859.1 - 2e-06 27.8 0.0 0.0052 16.9 0.0 3.5 3 0 0 3 3 3 2 Cupredoxin-like domain Gmad2 PF10648.9 AJA91859.1 - 0.16 12.2 0.1 0.16 12.2 0.1 3.4 3 1 1 4 4 4 0 Immunoglobulin-like domain of bacterial spore germination FlgD_ig PF13860.6 AJA91859.1 - 0.19 11.6 4.9 0.2 11.5 0.8 2.8 3 0 0 3 3 3 0 FlgD Ig-like domain CBM_2 PF00553.19 AJA91859.1 - 0.21 11.9 1.7 0.91 9.9 0.1 2.7 3 0 0 3 3 3 0 Cellulose binding domain PmbA_TldD PF01523.16 AJA91859.1 - 0.34 10.7 7.6 0.68 9.7 7.6 1.5 1 0 0 1 1 1 0 Putative modulator of DNA gyrase PPC PF04151.15 AJA91859.1 - 7.9 7.7 7.2 0.89 10.7 0.1 3.0 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain PAC2 PF09754.9 AJA91860.1 - 4.4e-25 89.0 0.0 5.2e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 PAC2 family MFS_1 PF07690.16 AJA91861.1 - 5.4e-25 88.1 42.0 1e-20 74.0 31.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AJA91861.1 - 0.022 13.6 34.1 0.72 8.6 33.4 2.3 1 1 0 1 1 1 0 MFS_1 like family Tail_VII PF17091.5 AJA91861.1 - 0.96 9.4 7.3 4.1 7.4 0.2 3.9 3 0 0 3 3 3 0 Inovirus G7P protein Metallophos PF00149.28 AJA91862.1 - 1.3e-10 42.2 1.9 6e-10 40.0 1.9 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AJA91862.1 - 4.2e-08 33.5 0.0 6.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.19 AJA91862.1 - 0.00083 18.3 0.1 0.0017 17.3 0.0 1.5 2 0 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase Exo_endo_phos_2 PF14529.6 AJA91862.1 - 0.077 12.9 1.6 0.16 11.8 1.6 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Epimerase PF01370.21 AJA91863.1 - 1.1e-19 70.8 0.0 1.4e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJA91863.1 - 4.1e-15 56.0 0.1 1.8e-14 53.9 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AJA91863.1 - 1.3e-10 40.7 0.3 6.7e-10 38.4 0.3 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AJA91863.1 - 5.1e-09 35.7 0.0 7.4e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AJA91863.1 - 4.9e-08 32.5 0.0 0.00051 19.3 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 AJA91863.1 - 0.0031 16.7 0.5 0.44 9.6 0.2 2.7 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 AJA91863.1 - 0.024 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 AJA91863.1 - 0.034 13.6 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 AJA91863.1 - 0.053 13.4 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Inos-1-P_synth PF01658.17 AJA91864.1 - 1.2e-27 96.3 0.0 2.1e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase TBP PF00352.21 AJA91865.1 - 6.4e-53 176.7 0.0 3.1e-26 91.1 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 AJA91865.1 - 3.6e-06 27.0 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Proton_antipo_M PF00361.20 AJA91866.1 - 4.9e-66 222.9 19.9 4.9e-66 222.9 19.9 2.4 2 1 1 3 3 3 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AJA91866.1 - 0.00021 21.3 0.1 0.0013 18.7 0.1 2.5 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus CopD PF05425.13 AJA91867.1 - 1.8e-13 50.8 4.3 1.4e-12 47.9 0.5 2.7 2 0 0 2 2 2 1 Copper resistance protein D CopC PF04234.12 AJA91867.1 - 7.8e-10 39.7 0.0 2e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 CopC domain SGL PF08450.12 AJA91867.1 - 1.5e-09 37.8 0.1 0.018 14.6 0.0 4.2 1 1 3 4 4 4 4 SMP-30/Gluconolactonase/LRE-like region YtkA PF13115.6 AJA91867.1 - 0.00071 20.1 0.1 0.025 15.2 0.0 2.6 2 0 0 2 2 2 1 YtkA-like DUF5074 PF16819.5 AJA91867.1 - 0.0052 16.8 0.1 0.087 12.9 0.0 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF5074) DUF4149 PF13664.6 AJA91867.1 - 0.011 16.1 1.7 0.011 16.1 1.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) PPC PF04151.15 AJA91867.1 - 0.018 16.1 1.6 0.075 14.1 1.6 2.0 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Reg_prop PF07494.11 AJA91867.1 - 0.025 14.7 10.8 2.6e+02 2.4 0.0 7.5 8 0 0 8 8 8 0 Two component regulator propeller TMEM173 PF15009.6 AJA91867.1 - 0.25 10.5 0.1 0.4 9.8 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 PKD PF00801.20 AJA91869.1 - 0.011 15.5 0.6 0.011 15.5 0.6 2.6 2 1 0 2 2 2 0 PKD domain ASH PF15780.5 AJA91869.1 - 0.019 15.1 0.0 0.066 13.4 0.0 1.8 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin NPAT_C PF15712.5 AJA91869.1 - 0.068 11.8 0.1 0.083 11.5 0.1 1.1 1 0 0 1 1 1 0 NPAT C terminus Carot_N PF09150.10 AJA91869.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal CdvA PF18822.1 AJA91870.1 - 1.6e-30 105.5 10.9 2.1e-30 105.1 10.9 1.2 1 0 0 1 1 1 1 CdvA-like coiled-coil domain PDDEXK_7 PF04411.12 AJA91870.1 - 0.0078 16.2 1.0 0.012 15.6 1.0 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF4775 PF16001.5 AJA91870.1 - 0.0088 15.5 13.2 0.013 15.0 13.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4775) YbaB_DNA_bd PF02575.16 AJA91870.1 - 0.13 12.5 3.0 0.26 11.5 2.7 1.7 1 1 0 1 1 1 0 YbaB/EbfC DNA-binding family ABC1 PF03109.16 AJA91871.1 - 3.1e-24 85.4 0.3 9.2e-24 83.9 0.0 1.9 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 AJA91871.1 - 0.0033 16.8 1.1 0.0091 15.4 1.1 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 AJA91871.1 - 0.0046 16.9 0.0 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 AJA91871.1 - 0.011 15.4 0.4 0.011 15.4 0.4 1.9 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF2207 PF09972.9 AJA91871.1 - 0.11 11.3 0.7 0.18 10.6 0.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ribosomal_L13 PF00572.18 AJA91872.1 - 3.1e-09 37.1 0.3 2.7e-07 30.9 0.1 2.6 1 1 1 2 2 2 1 Ribosomal protein L13 TRAF_BIRC3_bd PF16673.5 AJA91874.1 - 0.0054 16.5 0.4 0.01 15.6 0.4 1.4 1 0 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain Glycolytic PF00274.19 AJA91874.1 - 0.037 12.8 0.1 0.04 12.7 0.1 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Glyco_trans_1_2 PF13524.6 AJA91875.1 - 1.2e-05 25.6 0.0 1.9e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_3_5 PF16640.5 AJA91876.1 - 0.095 12.9 1.0 0.16 12.1 0.9 1.5 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 3) DUF4514 PF14986.6 AJA91876.1 - 2.1 8.4 5.3 6 6.9 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) 4HBT PF03061.22 AJA91877.1 - 2.1e-16 60.0 0.1 3.2e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 AJA91877.1 - 2.4e-05 23.9 0.3 3.3e-05 23.4 0.3 1.2 1 0 0 1 1 1 1 MaoC like domain DUF4442 PF14539.6 AJA91877.1 - 0.0053 16.9 0.2 0.019 15.1 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) DUF3426 PF11906.8 AJA91878.1 - 2.5e-15 56.9 0.1 2.1e-09 37.7 0.1 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF3426) DUF2393 PF09624.10 AJA91878.1 - 0.0013 18.8 5.6 0.35 10.8 0.9 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF2393) DUF3157 PF11355.8 AJA91878.1 - 0.022 14.4 0.3 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3157) Cadherin_4 PF17803.1 AJA91878.1 - 0.072 13.7 0.2 0.25 12.0 0.1 1.9 2 0 0 2 2 2 0 Bacterial cadherin-like domain Cadherin_5 PF17892.1 AJA91878.1 - 0.078 13.0 0.2 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Cadherin-like domain GbpC PF08363.10 AJA91878.1 - 0.093 12.2 2.5 0.32 10.4 0.1 2.0 2 0 0 2 2 2 0 Glucan-binding protein C DUF4352 PF11611.8 AJA91878.1 - 0.2 12.0 3.9 0.98 9.7 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4352) REPA_OB_2 PF16900.5 AJA91879.1 - 1.6e-05 24.7 0.6 1.9e-05 24.5 0.6 1.1 1 0 0 1 1 1 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 AJA91879.1 - 0.00027 20.9 0.2 0.00036 20.5 0.2 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain bPH_1 PF08000.11 AJA91879.1 - 0.038 14.1 0.1 0.047 13.8 0.1 1.1 1 0 0 1 1 1 0 Bacterial PH domain FKBP_C PF00254.28 AJA91880.1 - 1.5e-11 44.5 0.7 1.6e-10 41.2 0.2 2.6 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP26_C PF18046.1 AJA91880.1 - 5.2e-10 39.3 1.0 1.1e-09 38.2 1.0 1.6 1 0 0 1 1 1 1 FKBP26_C-terminal Ribosomal_S8e PF01201.22 AJA91881.1 - 4.2e-20 72.3 4.8 4.9e-20 72.1 4.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e zf-ribbon_3 PF13248.6 AJA91883.1 - 1.4 8.4 4.4 5.7 6.5 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 AJA91884.1 - 2.4e-06 27.7 6.7 0.00023 21.4 0.5 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 AJA91884.1 - 2.4e-06 27.9 7.9 0.0018 19.0 1.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-ribbon_3 PF13248.6 AJA91884.1 - 7.7e-05 22.0 0.6 0.31 10.5 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain zf-C2H2_11 PF16622.5 AJA91884.1 - 0.00012 21.8 4.7 0.26 11.1 3.6 2.9 2 1 0 2 2 2 2 zinc-finger C2H2-type zinc_ribbon_2 PF13240.6 AJA91884.1 - 0.00017 21.2 2.0 0.23 11.2 0.2 2.4 2 0 0 2 2 2 2 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AJA91884.1 - 0.00042 20.4 3.7 0.28 11.3 0.1 2.3 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 AJA91884.1 - 0.0015 18.0 2.0 1 8.9 0.1 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding zf-C2HC_2 PF13913.6 AJA91884.1 - 0.0015 18.3 2.9 0.0015 18.3 2.9 3.1 3 0 0 3 3 3 1 zinc-finger of a C2HC-type DUF2688 PF10892.8 AJA91884.1 - 0.0019 17.6 1.7 0.23 11.0 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2688) zf-HYPF PF07503.12 AJA91884.1 - 0.0054 16.5 5.0 0.3 10.9 1.3 2.2 2 0 0 2 2 2 2 HypF finger HypA PF01155.19 AJA91884.1 - 0.0055 16.7 5.2 0.32 11.0 0.7 2.0 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 AJA91884.1 - 0.0066 16.5 4.0 0.0094 16.0 4.0 1.4 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_4 PF13717.6 AJA91884.1 - 0.0074 16.2 0.5 0.0074 16.2 0.5 2.5 3 0 0 3 3 3 1 zinc-ribbon domain C1_1 PF00130.22 AJA91884.1 - 0.0083 16.0 1.9 0.023 14.6 1.9 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S27e PF01667.17 AJA91884.1 - 0.011 15.4 0.4 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 XPA_N PF01286.18 AJA91884.1 - 0.013 15.6 3.7 0.63 10.1 0.6 2.4 2 0 0 2 2 2 0 XPA protein N-terminal Ephrin_rec_like PF07699.13 AJA91884.1 - 0.013 15.3 1.6 0.53 10.1 0.1 2.1 2 0 0 2 2 2 0 Putative ephrin-receptor like RNA_POL_M_15KD PF02150.16 AJA91884.1 - 0.013 15.4 0.9 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit CpXC PF14353.6 AJA91884.1 - 0.018 15.1 2.7 0.41 10.7 2.8 2.0 1 1 1 2 2 2 0 CpXC protein DNA_RNApol_7kD PF03604.13 AJA91884.1 - 0.018 14.7 5.0 2.3 8.0 0.1 2.6 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf_UBZ PF18439.1 AJA91884.1 - 0.024 14.2 1.8 1.6 8.4 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 AJA91884.1 - 0.031 15.0 3.3 0.038 14.7 3.3 1.3 1 0 0 1 1 1 0 zinc-ribbon family Prok-RING_1 PF14446.6 AJA91884.1 - 0.035 14.0 5.5 1 9.3 1.2 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DUF35_N PF12172.8 AJA91884.1 - 0.057 13.3 1.1 6.7 6.7 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF983 PF06170.12 AJA91884.1 - 0.057 13.8 1.6 6.6 7.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zf-C2H2_8 PF15909.5 AJA91884.1 - 0.064 13.5 1.6 0.073 13.4 1.6 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon TFIIS_C PF01096.18 AJA91884.1 - 0.072 13.0 3.6 2.5 8.0 0.2 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.6 AJA91884.1 - 0.073 13.5 2.7 0.68 10.4 2.6 1.9 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf_C2H2_ZHX PF18387.1 AJA91884.1 - 0.092 12.4 1.4 6 6.6 0.2 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 AJA91884.1 - 0.13 12.6 4.9 2 8.8 0.2 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Rubredoxin_2 PF18073.1 AJA91884.1 - 0.18 11.6 3.4 4.9 7.0 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-BED PF02892.15 AJA91884.1 - 0.22 11.5 7.4 0.35 10.9 0.7 2.5 1 1 1 2 2 2 0 BED zinc finger OrfB_Zn_ribbon PF07282.11 AJA91884.1 - 0.25 11.3 8.8 0.29 11.1 6.9 1.9 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_5 PF13719.6 AJA91884.1 - 0.25 11.1 7.8 0.89 9.4 2.9 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 AJA91884.1 - 0.41 10.8 0.2 0.41 10.8 0.2 2.7 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-Mss51 PF13824.6 AJA91884.1 - 0.45 10.7 6.4 6.4 7.0 1.4 2.6 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_3 PF13878.6 AJA91884.1 - 0.54 10.1 9.9 1.7 8.5 0.3 2.8 2 1 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-IS66 PF13005.7 AJA91884.1 - 5.5 7.5 10.9 46 4.5 6.3 2.8 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 DBI_PRT PF02277.17 AJA91885.1 - 1.1e-13 51.1 0.0 1.5e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyltransferase EMG1 PF03587.14 AJA91886.1 - 1.7e-43 148.5 2.5 1.9e-43 148.4 2.5 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyco_transf_4 PF13439.6 AJA91886.1 - 0.2 11.6 0.0 0.3 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Methyltrn_RNA_3 PF02598.17 AJA91887.1 - 6e-46 157.2 0.0 6.8e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 AJA91887.1 - 0.042 14.0 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 SpoU rRNA Methylase family Methyltrn_RNA_4 PF09936.9 AJA91887.1 - 0.048 13.5 0.0 0.72 9.7 0.0 2.1 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase SIS_2 PF13580.6 AJA91888.1 - 3.4e-26 91.9 0.4 5.1e-26 91.3 0.4 1.2 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 AJA91888.1 - 2e-08 34.2 0.9 1.1e-05 25.2 0.1 2.2 1 1 0 2 2 2 2 SIS domain TPP_enzyme_M PF00205.22 AJA91888.1 - 0.04 13.7 0.1 0.074 12.8 0.1 1.6 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Fer4_12 PF13353.6 AJA91888.1 - 0.091 13.0 0.2 0.19 12.0 0.2 1.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain OmpA PF00691.20 AJA91888.1 - 0.1 13.0 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 OmpA family TBPIP PF07106.13 AJA91888.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain AAA_lid_6 PF17866.1 AJA91888.1 - 0.16 12.2 0.1 15 5.8 0.0 2.8 3 0 0 3 3 3 0 AAA lid domain Epimerase PF01370.21 AJA91889.1 - 1.3e-39 136.1 0.0 1.7e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJA91889.1 - 3.2e-29 102.4 0.1 4.3e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AJA91889.1 - 6.3e-28 97.7 0.0 8.2e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AJA91889.1 - 3.2e-19 69.0 2.0 4e-19 68.7 2.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AJA91889.1 - 2.7e-17 62.9 0.7 2.1e-16 59.9 0.7 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AJA91889.1 - 2.6e-11 43.2 0.0 4.9e-08 32.4 0.1 2.5 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 AJA91889.1 - 3.1e-06 27.2 0.0 4.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding O-FucT PF10250.9 AJA91889.1 - 0.0077 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Archaeal_AmoA PF12942.7 AJA91890.1 - 1.4e-92 308.5 11.7 1.6e-92 308.3 11.7 1.0 1 0 0 1 1 1 1 Archaeal ammonia monooxygenase subunit A (AmoA) Pho88 PF10032.9 AJA91891.1 - 0.064 12.5 0.1 0.086 12.1 0.1 1.2 1 0 0 1 1 1 0 Phosphate transport (Pho88) NeuB PF03102.14 AJA91891.1 - 0.074 12.5 0.6 0.17 11.3 0.1 1.6 1 1 1 2 2 2 0 NeuB family PPS_PS PF02006.16 AJA91892.1 - 1.1e-62 210.7 3.7 1.8e-62 210.0 3.7 1.3 1 0 0 1 1 1 1 Phosphopantothenate/pantothenate synthetase TPP_enzyme_M PF00205.22 AJA91892.1 - 0.018 14.8 0.3 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain CTP-dep_RFKase PF01982.16 AJA91893.1 - 9.9e-41 138.6 0.2 1.4e-40 138.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF120 HTH_20 PF12840.7 AJA91893.1 - 0.00043 20.3 0.0 0.00079 19.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 AJA91893.1 - 0.0011 18.9 0.2 0.0055 16.6 0.0 2.2 1 1 1 2 2 2 1 MarR family MarR_2 PF12802.7 AJA91893.1 - 0.0011 18.8 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_36 PF13730.6 AJA91893.1 - 0.002 18.0 0.1 0.055 13.4 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain DUF4364 PF14277.6 AJA91893.1 - 0.013 15.2 1.3 0.021 14.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) HTH_24 PF13412.6 AJA91893.1 - 0.016 14.8 0.0 0.052 13.1 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AJA91893.1 - 0.023 14.6 0.1 0.092 12.7 0.0 2.1 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AJA91893.1 - 0.031 14.2 0.1 0.06 13.3 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain RepL PF05732.11 AJA91893.1 - 0.033 13.6 1.6 0.078 12.4 0.1 2.0 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) LexA_DNA_bind PF01726.16 AJA91893.1 - 0.16 11.8 0.1 0.54 10.1 0.1 1.9 1 0 0 1 1 1 0 LexA DNA binding domain Na_Ca_ex PF01699.24 AJA91894.1 - 6.9e-40 136.5 44.7 5.1e-21 75.2 19.2 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Spore_YhaL PF14147.6 AJA91894.1 - 0.018 14.7 0.5 0.075 12.7 0.5 2.1 1 0 0 1 1 1 0 Sporulation protein YhaL Bmp PF02608.14 AJA91894.1 - 0.026 13.5 0.9 0.049 12.6 0.9 1.4 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like Ribosomal_L16 PF00252.18 AJA91895.1 - 9.1e-28 96.9 1.9 1.1e-27 96.7 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DeoC PF01791.9 AJA91896.1 - 2.3e-20 73.2 0.1 3.3e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase ThiG PF05690.14 AJA91896.1 - 0.0071 15.7 0.1 0.016 14.6 0.0 1.4 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG tRNA_bind PF01588.20 AJA91897.1 - 2.6e-23 81.9 0.0 2.9e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Putative tRNA binding domain DUF3990 PF13151.6 AJA91899.1 - 0.006 16.3 0.1 0.014 15.1 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3990) HpcH_HpaI PF03328.14 AJA91900.1 - 6.3e-06 25.5 0.0 8.4e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 AJA91900.1 - 1.1e-05 24.6 0.1 1.1e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain VAPB_antitox PF02697.14 AJA91900.1 - 0.021 15.6 0.2 0.021 15.6 0.2 2.4 3 2 0 3 3 3 0 Putative antitoxin PEPcase_2 PF14010.6 AJA91900.1 - 0.081 11.4 0.7 0.095 11.2 0.7 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DPRP PF04244.13 AJA91901.1 - 1.9e-79 266.7 2.9 1.9e-79 266.7 2.9 1.9 2 0 0 2 2 2 1 Deoxyribodipyrimidine photo-lyase-related protein NYN_YacP PF05991.11 AJA91901.1 - 0.0012 18.9 0.1 0.0025 17.8 0.1 1.5 1 0 0 1 1 1 1 YacP-like NYN domain IF4E PF01652.18 AJA91901.1 - 0.03 14.1 2.2 0.064 13.0 0.3 2.4 2 0 0 2 2 2 0 Eukaryotic initiation factor 4E RNA_pol_Rpb5_N PF03871.14 AJA91901.1 - 0.16 12.5 2.2 6.2 7.5 0.5 3.5 3 0 0 3 3 3 0 RNA polymerase Rpb5, N-terminal domain PEP_mutase PF13714.6 AJA91903.1 - 1.5e-51 175.2 0.0 1.7e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 AJA91903.1 - 2.8e-13 49.2 0.1 4.1e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Glycolytic PF00274.19 AJA91903.1 - 0.038 12.7 0.1 0.055 12.2 0.1 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I DUF1297 PF06973.12 AJA91905.1 - 6.8e-74 247.5 0.2 1.2e-73 246.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.12 AJA91905.1 - 2.6e-46 156.6 0.0 4.8e-46 155.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) DHquinase_I PF01487.15 AJA91906.1 - 1.8e-53 182.1 0.0 2.2e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Type I 3-dehydroquinase Gly_transf_sug PF04488.15 AJA91906.1 - 0.081 13.6 0.7 0.33 11.6 0.3 2.0 2 0 0 2 2 2 0 Glycosyltransferase sugar-binding region containing DXD motif NOP5NT PF08156.13 AJA91906.1 - 0.087 13.2 1.1 1.3 9.5 0.8 2.5 1 1 1 2 2 2 0 NOP5NT (NUC127) domain Ribosomal_S3_C PF00189.20 AJA91907.1 - 2e-20 73.1 0.4 4.4e-20 72.0 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AJA91907.1 - 1.4e-13 50.4 0.1 4e-13 49.0 0.1 1.8 1 0 0 1 1 1 1 KH domain KH_1 PF00013.29 AJA91907.1 - 0.071 12.9 2.2 2.1 8.2 0.1 3.2 3 0 0 3 3 3 0 KH domain CSN5_C PF18323.1 AJA91907.1 - 0.35 11.8 2.9 1.5 9.8 1.3 2.5 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain GTP_EFTU_D2 PF03144.25 AJA91908.1 - 5.3e-09 36.4 0.1 1.1e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 T2SSE PF00437.20 AJA91909.1 - 6.1e-14 51.7 0.0 8.7e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein KH_1 PF00013.29 AJA91909.1 - 2.2e-06 27.4 0.1 7.5e-06 25.7 0.0 2.0 2 0 0 2 2 1 1 KH domain AAA_16 PF13191.6 AJA91909.1 - 0.0003 21.2 0.0 0.00053 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 AJA91909.1 - 0.0023 17.2 0.0 0.0037 16.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_29 PF13555.6 AJA91909.1 - 0.004 16.9 0.0 0.0098 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 AJA91909.1 - 0.0051 16.1 0.1 0.02 14.2 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin MeaB PF03308.16 AJA91909.1 - 0.0055 15.7 0.0 0.0088 15.0 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 AJA91909.1 - 0.0061 17.1 0.0 0.017 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AJA91909.1 - 0.013 15.5 0.0 0.049 13.5 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 AJA91909.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain KH_2 PF07650.17 AJA91909.1 - 0.03 14.1 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 KH domain AAA_28 PF13521.6 AJA91909.1 - 0.031 14.5 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AJA91909.1 - 0.034 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 AJA91909.1 - 0.035 14.1 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 AJA91909.1 - 0.052 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 AJA91909.1 - 0.061 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 AJA91909.1 - 0.064 13.0 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 AJA91909.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 AJA91909.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 AJA91909.1 - 0.099 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 KH_4 PF13083.6 AJA91909.1 - 0.11 12.4 1.9 0.13 12.2 0.0 2.1 2 0 0 2 2 1 0 KH domain RuvB_N PF05496.12 AJA91909.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AJA91909.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AJA91909.1 - 0.17 12.0 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 AJA91909.1 - 0.22 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 AJA91909.1 - 0.22 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Nodulin_late PF07127.11 AJA91910.1 - 0.23 11.8 2.3 0.32 11.3 2.3 1.3 1 0 0 1 1 1 0 Late nodulin protein RVT_3 PF13456.6 AJA91911.1 - 8.9e-11 41.7 0.0 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 AJA91911.1 - 2.2e-10 40.9 0.0 2.3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 RNase H HAD_SAK_1 PF10307.9 AJA91911.1 - 0.033 14.0 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins SHS2_Rpb7-N PF03876.17 AJA91914.1 - 4e-15 55.9 0.0 8.7e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 AJA91914.1 - 1.2e-12 48.0 0.0 2.6e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.6 AJA91914.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 S1 domain BPL_C PF02237.17 AJA91914.1 - 0.037 13.9 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Spt5-NGN PF03439.13 AJA91915.1 - 7.7e-19 67.4 0.0 1.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 AJA91915.1 - 1.8e-06 27.7 0.4 3.6e-06 26.7 0.4 1.5 1 0 0 1 1 1 1 KOW motif Metallophos_2 PF12850.7 AJA91916.1 - 5.4e-12 46.2 0.0 8.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AJA91916.1 - 3.5e-11 44.0 0.3 8e-11 42.8 0.3 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase ABC_tran_CTD PF16326.5 AJA91916.1 - 0.53 10.6 5.6 4.6 7.6 2.5 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain AA_kinase PF00696.28 AJA91917.1 - 1.3e-29 103.5 0.5 2.7e-29 102.5 0.5 1.5 1 1 0 1 1 1 1 Amino acid kinase family DUF4116 PF13475.6 AJA91917.1 - 0.0086 15.8 0.7 0.024 14.4 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4116) DUF5039 PF16442.5 AJA91917.1 - 0.052 13.1 0.2 0.32 10.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5039) DUF3810 PF12725.7 AJA91917.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ACT PF01842.25 AJA91917.1 - 0.43 10.4 4.4 0.21 11.4 0.7 2.4 3 0 0 3 3 3 0 ACT domain tRNA-synt_1b PF00579.25 AJA91918.1 - 8e-28 97.6 0.0 1.6e-27 96.6 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 AJA91918.1 - 0.064 12.2 0.0 0.72 8.7 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (K) Thy1 PF02511.15 AJA91919.1 - 2.7e-32 112.1 1.7 3.4e-18 66.1 1.6 2.4 2 0 0 2 2 2 2 Thymidylate synthase complementing protein FadA PF09403.10 AJA91919.1 - 2.6 8.6 14.3 2.7 8.5 0.5 3.6 3 0 0 3 3 3 0 Adhesion protein FadA RimK PF08443.11 AJA91920.1 - 1.2e-30 106.5 0.0 1.5e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 AJA91920.1 - 1.5e-09 37.6 0.2 1.2e-05 24.7 0.0 2.8 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 AJA91920.1 - 2.3e-09 36.9 0.1 2.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 AJA91920.1 - 4.4e-09 36.6 0.2 1.1e-08 35.3 0.2 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AJA91920.1 - 5.6e-06 26.0 0.0 2.2e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 AJA91920.1 - 8.9e-05 21.9 0.0 0.33 10.2 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp CPSase_L_D2 PF02786.17 AJA91920.1 - 0.0025 17.4 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_5 PF13549.6 AJA91920.1 - 0.0033 16.9 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HNH_repeat PF18780.1 AJA91920.1 - 0.033 14.0 0.3 0.084 12.7 0.3 1.7 1 0 0 1 1 1 0 Homing endonuclease repeat CutA1 PF03091.15 AJA91921.1 - 6.3e-35 119.0 0.6 6.9e-35 118.9 0.6 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Aminotran_3 PF00202.21 AJA91922.1 - 1.2e-114 383.2 0.0 1.4e-114 382.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AJA91922.1 - 7.7e-05 22.0 0.0 0.00013 21.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AJA91922.1 - 0.036 13.0 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Ter PF05472.11 AJA91922.1 - 0.083 11.9 0.6 0.15 11.0 0.1 1.5 2 0 0 2 2 2 0 DNA replication terminus site-binding protein (Ter protein) IFRD PF05004.13 AJA91922.1 - 0.092 11.8 0.1 0.17 11.0 0.0 1.4 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Lentiviral_Tat PF02998.14 AJA91923.1 - 0.19 11.8 0.0 0.21 11.6 0.0 1.1 1 0 0 1 1 1 0 Lentiviral Tat protein PCNA_N PF00705.18 AJA91924.1 - 6.3e-20 71.2 0.1 3.1e-19 68.9 0.0 1.9 1 1 1 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 AJA91924.1 - 5.6e-19 68.6 0.2 4e-17 62.6 0.0 2.7 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 AJA91924.1 - 0.0027 17.2 0.0 0.0036 16.8 0.0 1.1 1 0 0 1 1 1 1 Rad9 Tnp_22_dsRBD PF17490.2 AJA91924.1 - 0.071 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain His_biosynth PF00977.21 AJA91925.1 - 1.3e-66 224.3 1.1 1.5e-66 224.1 1.1 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Trp_syntA PF00290.20 AJA91925.1 - 0.0057 15.5 0.6 0.11 11.3 0.1 2.1 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PcrB PF01884.17 AJA91925.1 - 0.011 15.2 0.6 0.25 10.8 0.1 2.1 2 0 0 2 2 2 0 PcrB family G3P_antiterm PF04309.12 AJA91925.1 - 0.011 15.1 0.5 0.82 9.1 0.1 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 AJA91925.1 - 0.021 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG NMO PF03060.15 AJA91925.1 - 0.023 14.1 0.1 0.1 12.0 0.0 1.8 1 1 0 2 2 2 0 Nitronate monooxygenase Dus PF01207.17 AJA91925.1 - 0.11 11.6 0.1 8.8 5.3 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Iron_traffic PF04362.14 AJA91926.1 - 2.6e-06 27.0 2.5 6.2e-06 25.8 2.5 1.8 1 1 0 1 1 1 1 Bacterial Fe(2+) trafficking FYVE PF01363.21 AJA91926.1 - 0.0086 16.2 1.2 0.012 15.7 1.2 1.2 1 0 0 1 1 1 1 FYVE zinc finger zf-RRPl_C4 PF17026.5 AJA91926.1 - 0.022 14.9 1.3 0.031 14.4 1.3 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf_UBZ PF18439.1 AJA91926.1 - 0.049 13.2 1.1 0.049 13.2 1.1 1.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger ZZ PF00569.17 AJA91926.1 - 0.083 12.7 1.1 0.19 11.6 1.1 1.6 1 1 0 1 1 1 0 Zinc finger, ZZ type DUF3039 PF11238.8 AJA91926.1 - 0.19 11.5 2.6 0.68 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) zinc_ribbon_2 PF13240.6 AJA91926.1 - 0.21 11.4 3.4 0.56 10.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain PAC2 PF09754.9 AJA91927.1 - 7.8e-43 147.0 0.0 9e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 PAC2 family LysE PF01810.18 AJA91928.1 - 7.7e-30 103.8 15.6 9e-30 103.6 15.6 1.0 1 0 0 1 1 1 1 LysE type translocator SIS PF01380.22 AJA91929.1 - 7.3e-47 158.5 1.4 3e-25 88.6 0.9 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 AJA91929.1 - 3.1e-21 76.0 0.0 5.5e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AJA91929.1 - 4e-16 59.0 0.1 1.4e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain SIS_2 PF13580.6 AJA91929.1 - 2.2e-06 27.7 1.3 0.00013 22.0 0.2 3.2 2 1 1 3 3 3 1 SIS domain GATase_4 PF13230.6 AJA91929.1 - 2.5e-05 23.3 0.0 5.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Asparaginase_2 PF01112.18 AJA91929.1 - 0.057 12.4 0.4 2.2 7.3 0.0 2.7 3 0 0 3 3 3 0 Asparaginase Glyco_trans_4_2 PF13477.6 AJA91930.1 - 0.0014 18.7 0.1 0.0029 17.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase 4-like UDPG_MGDP_dh_N PF03721.14 AJA91930.1 - 0.0015 18.1 0.0 0.4 10.2 0.0 2.5 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 AJA91930.1 - 0.19 12.0 0.0 0.66 10.2 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain ZnuA PF01297.17 AJA91931.1 - 3.9e-72 242.7 2.5 4.7e-72 242.5 2.5 1.1 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic DNA_pol_phi PF04931.13 AJA91931.1 - 0.18 9.9 15.0 0.27 9.3 15.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 AJA91931.1 - 0.19 10.0 3.4 0.22 9.8 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3915 PF13054.6 AJA91931.1 - 0.28 11.2 3.4 0.79 9.7 2.6 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3915) NOA36 PF06524.12 AJA91931.1 - 0.44 9.8 12.1 0.63 9.3 12.1 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 AJA91931.1 - 1.5 8.2 10.7 2.1 7.7 10.7 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 AJA91931.1 - 3.4 6.7 15.7 4.8 6.2 15.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 AJA91931.1 - 8.2 4.8 6.7 11 4.4 6.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ribosomal_S24e PF01282.19 AJA91932.1 - 5.4e-08 32.7 0.2 8.6e-08 32.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e THUMP PF02926.17 AJA91933.1 - 2e-10 40.9 2.1 2.8e-10 40.5 2.1 1.2 1 0 0 1 1 1 1 THUMP domain CDT1_C PF16679.5 AJA91933.1 - 0.0028 18.0 0.1 0.0054 17.1 0.1 1.4 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain KH_10 PF17905.1 AJA91933.1 - 0.014 15.8 0.9 0.027 14.9 0.9 1.4 1 0 0 1 1 1 0 GLD-3 KH domain 5 CENP-H PF05837.12 AJA91933.1 - 0.047 14.1 0.8 0.074 13.5 0.8 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CBM_4_9 PF02018.17 AJA91934.1 - 0.01 16.1 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain HEAT_2 PF13646.6 AJA91935.1 - 5.8e-20 71.5 0.0 3.1e-13 49.9 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 AJA91935.1 - 1.6e-14 52.7 0.4 0.011 15.9 0.0 4.3 4 0 0 4 4 4 3 HEAT repeat HEAT_PBS PF03130.16 AJA91935.1 - 3.9e-09 36.3 0.0 0.14 12.9 0.0 4.3 4 0 0 4 4 4 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 AJA91935.1 - 8.1e-09 35.8 0.0 0.011 16.2 0.0 4.1 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 AJA91935.1 - 1.6e-06 28.2 0.1 0.0032 17.5 0.0 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 AJA91935.1 - 0.00015 21.7 0.2 0.41 10.8 0.0 3.7 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 AJA91935.1 - 0.068 11.7 0.0 1.1 7.8 0.0 2.1 1 1 1 2 2 2 0 Adaptin N terminal region DUF4042 PF13251.6 AJA91935.1 - 0.2 11.3 0.0 25 4.5 0.0 2.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4042) HIT PF01230.23 AJA91936.1 - 1.5e-23 83.4 0.1 1.9e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AJA91936.1 - 1.5e-11 44.8 0.1 1.7e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA_26 PF13500.6 AJA91937.1 - 6.1e-40 137.2 0.0 7.5e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AJA91937.1 - 2.3e-07 30.9 0.0 3.7e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 AJA91937.1 - 0.001 18.4 0.4 0.025 13.8 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1611_C) P-loop domain PuR_N PF09182.10 AJA91937.1 - 0.12 12.3 0.3 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal PI3K_p85B PF02192.16 AJA91938.1 - 0.071 12.9 0.2 0.083 12.6 0.2 1.2 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain ADH_zinc_N PF00107.26 AJA91939.1 - 5.1e-26 91.2 0.0 9.4e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AJA91939.1 - 1.6e-22 79.5 0.1 2.5e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 AJA91939.1 - 5.9e-17 63.0 0.0 9.4e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1454 PF07305.12 AJA91940.1 - 0.068 12.6 0.1 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) VWA PF00092.28 AJA91942.1 - 1.3e-25 90.6 0.1 2.6e-25 89.6 0.1 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 AJA91942.1 - 2.1e-20 73.4 0.0 4e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain BatA PF07584.11 AJA91942.1 - 3e-10 40.3 1.2 3.2e-10 40.2 0.1 1.6 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal DUF1194 PF06707.11 AJA91942.1 - 0.0021 17.3 0.2 0.01 15.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1194) VWA_CoxE PF05762.14 AJA91942.1 - 0.0035 16.8 0.0 0.009 15.4 0.0 1.6 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein Ssl1 PF04056.14 AJA91942.1 - 0.01 15.7 0.0 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 Ssl1-like Ribosomal_L37e PF01907.19 AJA91943.1 - 1.2e-21 76.6 10.9 1.2e-21 76.5 10.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L37e OrfB_Zn_ribbon PF07282.11 AJA91943.1 - 0.0082 16.1 1.6 0.011 15.7 1.6 1.2 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HypA PF01155.19 AJA91943.1 - 0.01 15.8 0.5 0.011 15.7 0.5 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_RNApol_7kD PF03604.13 AJA91943.1 - 0.04 13.6 5.4 0.074 12.7 0.9 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Rubredoxin_2 PF18073.1 AJA91943.1 - 0.091 12.5 5.5 0.95 9.2 0.6 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain MraY_sig1 PF10555.9 AJA91943.1 - 0.2 11.3 0.7 0.36 10.4 0.7 1.5 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 zf-Mss51 PF13824.6 AJA91943.1 - 0.31 11.2 5.1 1.9 8.6 0.4 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.6 AJA91943.1 - 0.36 10.3 5.0 5.5 6.5 5.2 2.1 1 1 1 2 2 2 0 zinc-ribbon domain BPL_LplA_LipB PF03099.19 AJA91944.1 - 2.8e-19 69.3 0.0 6.8e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.12 AJA91944.1 - 1e-14 54.2 0.1 3.6e-14 52.4 0.1 2.0 1 0 0 1 1 1 1 HTH domain BPL_C PF02237.17 AJA91944.1 - 1.5e-10 40.8 0.7 2.9e-10 39.9 0.7 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain UPF0122 PF04297.14 AJA91944.1 - 0.03 14.6 0.9 0.062 13.6 0.1 1.9 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like BPL_LplA_LipB_2 PF16917.5 AJA91944.1 - 0.033 13.7 0.0 0.063 12.8 0.0 1.5 1 1 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Phage_X PF05155.15 AJA91944.1 - 0.04 14.3 0.1 6.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Phage X family Vert_IL3-reg_TF PF06529.11 AJA91945.1 - 0.01 15.0 1.0 0.012 14.8 1.0 1.0 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor KxDL PF10241.9 AJA91945.1 - 0.043 14.1 2.1 0.11 12.8 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein COMM_domain PF07258.14 AJA91945.1 - 0.087 12.9 2.5 0.95 9.6 0.2 2.3 2 0 0 2 2 2 0 COMM domain HTH_45 PF14947.6 AJA91946.1 - 1.8e-10 40.7 0.5 2.1e-10 40.4 0.5 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix Baculo_LEF5 PF04838.12 AJA91946.1 - 0.0098 15.9 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 HSP33 PF01430.19 AJA91946.1 - 0.013 14.9 0.1 0.019 14.4 0.0 1.3 1 1 0 1 1 1 0 Hsp33 protein FtsK_gamma PF09397.10 AJA91946.1 - 0.02 14.7 0.1 0.03 14.1 0.1 1.3 1 0 0 1 1 1 0 Ftsk gamma domain AUX_IAA PF02309.16 AJA91946.1 - 0.11 12.3 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 AUX/IAA family TFIIB PF00382.19 AJA91947.1 - 1.4e-30 105.1 6.7 7.8e-15 54.7 0.4 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJA91947.1 - 2.9e-09 36.3 1.0 4.9e-09 35.5 1.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_11 PF08279.12 AJA91947.1 - 0.0048 16.8 0.2 0.19 11.7 0.0 2.6 2 0 0 2 2 2 1 HTH domain Cyclin_N PF00134.23 AJA91947.1 - 0.0085 15.8 0.3 0.017 14.9 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sigma70_r4 PF04545.16 AJA91947.1 - 0.013 15.1 0.0 0.039 13.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AJA91947.1 - 0.021 14.5 0.3 0.29 10.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.6 AJA91947.1 - 0.032 14.1 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain zinc_ribbon_2 PF13240.6 AJA91947.1 - 0.037 13.7 2.0 0.067 12.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HTH_23 PF13384.6 AJA91947.1 - 0.05 13.4 0.5 0.54 10.1 0.0 2.7 3 0 0 3 3 3 0 Homeodomain-like domain RPW8 PF05659.11 AJA91947.1 - 0.067 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RB_B PF01857.20 AJA91947.1 - 0.078 13.0 0.1 0.14 12.2 0.1 1.5 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain Rep_fac-A_C PF08646.10 AJA91947.1 - 0.1 12.3 4.7 0.27 11.0 1.1 2.6 3 0 0 3 3 3 0 Replication factor-A C terminal domain RPA_interact_C PF14768.6 AJA91947.1 - 0.11 13.1 0.0 0.29 11.7 0.0 1.8 1 0 0 1 1 1 0 Replication protein A interacting C-terminal zf-piccolo PF05715.13 AJA91947.1 - 0.13 12.5 0.6 0.28 11.3 0.6 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger Phage_terminase PF10668.9 AJA91947.1 - 0.13 12.3 1.3 1.4 9.0 0.0 3.0 4 0 0 4 4 4 0 Phage terminase small subunit OrfB_Zn_ribbon PF07282.11 AJA91947.1 - 7 6.6 6.3 2 8.4 1.2 2.5 3 0 0 3 3 2 0 Putative transposase DNA-binding domain Mrr_cat PF04471.12 AJA91949.1 - 5.3e-05 23.2 0.0 9.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease ATP_bind_3 PF01171.20 AJA91950.1 - 8e-22 77.9 0.0 1.4e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 AJA91950.1 - 7e-06 25.1 0.0 1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 AJA91950.1 - 2.5e-05 23.6 0.0 3.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 NAD synthase PAPS_reduct PF01507.19 AJA91950.1 - 9.4e-05 22.5 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 AJA91950.1 - 0.013 15.0 0.1 0.042 13.3 0.1 2.0 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 AJA91950.1 - 0.025 14.1 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Glycos_transf_2 PF00535.26 AJA91951.1 - 5.7e-24 84.8 0.2 7.9e-24 84.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AJA91951.1 - 0.00022 21.2 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AJA91951.1 - 0.16 12.5 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Promethin PF16015.5 AJA91951.1 - 1.4 8.8 6.4 2.3 8.2 6.4 1.3 1 0 0 1 1 1 0 Promethin DUF202 PF02656.15 AJA91951.1 - 4.5 7.8 6.1 11 6.6 6.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) HEAT_2 PF13646.6 AJA91952.1 - 1.2e-12 48.1 0.1 1.4e-05 25.4 0.0 2.5 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 AJA91952.1 - 0.00018 21.5 0.0 1.5 9.3 0.0 4.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 AJA91952.1 - 0.00062 20.2 0.0 3.3 8.3 0.0 3.6 3 1 1 4 4 4 1 HEAT-like repeat ERAP1_C PF11838.8 AJA91952.1 - 0.0073 15.9 0.1 0.015 14.9 0.1 1.5 1 1 0 1 1 1 1 ERAP1-like C-terminal domain DUF1175 PF06672.11 AJA91952.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) DUF1495 PF07381.11 AJA91952.1 - 0.018 14.9 0.2 4.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) LpxI_N PF17930.1 AJA91952.1 - 0.063 13.2 1.2 0.7 9.8 0.1 2.5 3 0 0 3 3 3 0 LpxI N-terminal domain Sigma_reg_C PF13791.6 AJA91952.1 - 0.068 13.4 0.2 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 Sigma factor regulator C-terminal Vac14_Fab1_bd PF12755.7 AJA91952.1 - 0.079 13.6 0.1 2.3 8.8 0.0 3.0 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region DUF1059 PF06348.11 AJA91953.1 - 2.6e-19 69.2 1.0 2.9e-19 69.0 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) Sina PF03145.16 AJA91953.1 - 0.089 12.7 0.1 0.093 12.7 0.1 1.1 1 0 0 1 1 1 0 Seven in absentia protein family RNA_pol_Rpb5_C PF01191.19 AJA91955.1 - 5.8e-25 87.0 0.0 6.5e-25 86.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain zf-BED PF02892.15 AJA91956.1 - 0.00064 19.7 0.2 0.00085 19.3 0.2 1.3 1 0 0 1 1 1 1 BED zinc finger zf-C2H2 PF00096.26 AJA91956.1 - 0.0007 19.9 0.4 0.0007 19.9 0.4 1.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 AJA91956.1 - 0.0019 17.9 0.3 0.0031 17.2 0.3 1.3 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 AJA91956.1 - 0.0019 18.9 0.2 0.0019 18.9 0.2 1.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 AJA91956.1 - 0.011 15.6 2.9 0.015 15.2 0.0 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 AJA91956.1 - 0.014 15.2 0.0 0.014 15.2 0.0 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 AJA91956.1 - 0.021 15.2 0.0 0.023 15.0 0.0 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3 PF13878.6 AJA91956.1 - 0.026 14.3 0.9 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO RAG1_imp_bd PF12560.8 AJA91956.1 - 0.029 13.9 0.1 0.031 13.8 0.1 1.1 1 0 0 1 1 1 0 RAG1 importin binding DUF629 PF04780.12 AJA91956.1 - 0.2 10.2 0.0 0.2 10.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) THF_DHG_CYH_C PF02882.19 AJA91957.1 - 2.1e-58 196.2 1.7 3.3e-58 195.5 1.7 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 AJA91957.1 - 1.6e-38 131.5 0.5 2.7e-38 130.8 0.5 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IF2_N PF04760.15 AJA91957.1 - 0.0017 18.1 0.3 0.048 13.5 0.1 2.7 3 0 0 3 3 3 1 Translation initiation factor IF-2, N-terminal region Semialdhyde_dh PF01118.24 AJA91957.1 - 0.006 17.0 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Hydrolase PF00702.26 AJA91957.1 - 0.019 15.3 0.1 0.032 14.5 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AlaDh_PNT_C PF01262.21 AJA91957.1 - 0.028 13.7 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GTP_EFTU PF00009.27 AJA91958.1 - 1.7e-28 99.5 0.2 8e-28 97.3 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 AJA91958.1 - 3.4e-24 84.9 1.4 9.2e-24 83.5 0.1 2.4 3 0 0 3 3 3 1 Initiation factor eIF2 gamma, C terminal MMR_HSR1 PF01926.23 AJA91958.1 - 2e-05 24.7 0.0 3.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AJA91958.1 - 0.00017 21.9 0.8 0.00038 20.8 0.4 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 AJA91958.1 - 0.00059 19.8 1.6 0.009 15.9 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 AJA91958.1 - 0.015 15.3 0.1 0.035 14.1 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 AJA91958.1 - 0.052 13.1 0.8 4.7 6.7 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B HypA PF01155.19 AJA91958.1 - 0.095 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ILEI PF15711.5 AJA91958.1 - 0.097 13.2 0.0 0.78 10.3 0.0 2.4 2 0 0 2 2 2 0 Interleukin-like EMT inducer COX1 PF00115.20 AJA91959.1 - 1.5e-128 429.3 63.1 1.8e-128 429.1 63.1 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I P-II PF00543.22 AJA91961.1 - 4.9e-05 23.9 0.2 6.6e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II adh_short PF00106.25 AJA91962.1 - 3.9e-37 127.6 0.0 1.3e-31 109.6 0.0 3.1 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 AJA91962.1 - 6.7e-34 117.5 0.0 9.1e-25 87.6 0.0 3.7 3 1 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJA91962.1 - 4.1e-12 46.4 0.0 1.2e-09 38.3 0.0 2.7 2 1 1 3 3 3 1 KR domain Polysacc_synt_2 PF02719.15 AJA91962.1 - 0.0011 18.1 0.2 0.0025 17.0 0.2 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AJA91962.1 - 0.0023 17.4 0.0 0.0074 15.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJA91962.1 - 0.01 15.2 0.0 0.025 14.0 0.0 1.7 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Thioredoxin_15 PF18403.1 AJA91962.1 - 0.015 15.2 0.2 0.042 13.8 0.2 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain DUF4899 PF16240.5 AJA91962.1 - 0.026 13.7 1.6 0.19 10.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4899) 3HCDH_N PF02737.18 AJA91962.1 - 0.027 14.3 3.4 0.028 14.3 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 AJA91962.1 - 0.06 13.9 0.3 0.39 11.3 0.2 2.5 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PHB_acc_N PF07879.11 AJA91962.1 - 0.13 12.3 0.4 11 6.2 0.0 3.0 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain RNA_binding PF01877.17 AJA91963.1 - 1.1e-22 80.5 4.1 1.4e-22 80.2 4.1 1.1 1 0 0 1 1 1 1 RNA binding Phosphonate-bd PF12974.7 AJA91963.1 - 0.053 13.1 0.0 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Glyco_transf_7C PF02709.14 AJA91963.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase RMMBL PF07521.12 AJA91964.1 - 2.6e-15 56.1 0.1 6.4e-15 54.8 0.1 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 AJA91964.1 - 8.3e-14 51.8 0.0 1.5e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 AJA91964.1 - 1.9e-11 43.8 0.0 4.8e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 AJA91964.1 - 3.5e-11 43.5 0.0 2.7e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AJA91964.1 - 2.2e-07 30.6 0.0 4.6e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AJA91964.1 - 0.00027 20.8 0.0 0.001 19.0 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 AJA91964.1 - 0.0035 16.6 0.0 0.0077 15.5 0.0 1.6 1 1 0 1 1 1 1 Putative beta-lactamase-like family tRNA-synt_1e PF01406.19 AJA91965.1 - 2.2e-121 404.9 0.4 3.8e-121 404.1 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 AJA91965.1 - 1e-12 48.3 1.5 2.3e-12 47.2 0.3 2.3 2 1 1 3 3 3 1 DALR domain tRNA-synt_1g PF09334.11 AJA91965.1 - 3.2e-10 39.3 0.4 0.00021 20.1 0.4 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AJA91965.1 - 7.7e-08 31.0 1.3 8.6e-06 24.3 0.0 3.3 3 1 1 4 4 4 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 AJA91965.1 - 3.1e-07 29.6 0.3 0.0053 15.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) UVR PF02151.19 AJA91965.1 - 0.0025 17.5 0.5 0.016 14.9 0.5 2.4 1 0 0 1 1 1 1 UvrB/uvrC motif Lig_C PF18330.1 AJA91965.1 - 0.023 14.7 0.5 0.11 12.5 0.1 2.3 2 1 1 3 3 3 0 Ligase Pab1020 C-terminal region DNA_pol3_a_NII PF11490.8 AJA91965.1 - 0.21 11.5 5.8 0.99 9.3 0.1 2.6 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II AAA PF00004.29 AJA91966.1 - 1.8e-90 300.2 0.0 2.1e-48 164.1 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AJA91966.1 - 5.3e-30 103.0 2.3 1.8e-14 53.3 0.5 2.6 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 AJA91966.1 - 6.4e-26 90.4 1.4 2.1e-25 88.7 0.6 2.4 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 AJA91966.1 - 1.5e-15 57.3 0.0 1.2e-08 34.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 AJA91966.1 - 5.5e-13 49.4 0.0 2.8e-08 34.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AJA91966.1 - 1.7e-12 48.0 0.2 0.0018 18.7 0.0 4.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 AJA91966.1 - 4e-11 43.1 0.0 6.8e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 AJA91966.1 - 1.3e-10 41.6 0.0 0.00062 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 AJA91966.1 - 3.1e-10 40.5 0.2 0.0052 17.1 0.0 4.2 3 1 1 4 4 4 2 AAA domain AAA_5 PF07728.14 AJA91966.1 - 4.7e-10 39.6 0.3 0.00038 20.5 0.0 4.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 AJA91966.1 - 9.6e-10 38.8 0.1 0.00089 19.2 0.0 3.8 3 1 1 4 4 3 2 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AJA91966.1 - 2.2e-09 37.2 0.1 0.093 12.3 0.0 4.3 4 1 0 4 4 4 3 AAA domain RNA_helicase PF00910.22 AJA91966.1 - 4.4e-09 36.7 0.0 0.0017 18.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase CDC48_2 PF02933.17 AJA91966.1 - 1.1e-08 34.8 0.1 6.2e-08 32.3 0.1 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 ABC_tran PF00005.27 AJA91966.1 - 7.2e-08 33.0 0.3 0.0048 17.4 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_18 PF13238.6 AJA91966.1 - 1.9e-07 31.6 0.0 0.018 15.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 AJA91966.1 - 3.2e-07 30.7 0.0 0.033 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 AJA91966.1 - 4.7e-07 29.4 0.4 0.017 14.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AJA91966.1 - 5.3e-07 29.5 0.0 0.051 13.3 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 AJA91966.1 - 8.5e-07 29.1 0.7 0.056 13.4 0.0 3.8 2 2 2 4 4 4 2 Rad17 P-loop domain AAA_24 PF13479.6 AJA91966.1 - 1.4e-06 28.2 0.0 0.033 13.9 0.0 3.4 3 1 0 3 3 3 2 AAA domain NACHT PF05729.12 AJA91966.1 - 2.7e-06 27.4 0.2 0.23 11.4 0.1 3.4 3 0 0 3 3 3 2 NACHT domain Sigma54_activ_2 PF14532.6 AJA91966.1 - 4e-06 27.0 0.0 0.058 13.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain TIP49 PF06068.13 AJA91966.1 - 1.3e-05 24.6 0.1 0.07 12.3 0.0 3.2 3 1 0 3 3 3 2 TIP49 P-loop domain ATPase PF06745.13 AJA91966.1 - 2e-05 24.1 0.7 0.32 10.3 0.0 3.5 2 2 2 4 4 4 2 KaiC TsaE PF02367.17 AJA91966.1 - 5.3e-05 23.2 0.0 0.22 11.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 AJA91966.1 - 5.4e-05 22.6 0.0 0.043 13.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Viral_helicase1 PF01443.18 AJA91966.1 - 7.7e-05 22.5 0.0 0.1 12.3 0.0 2.8 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 AJA91966.1 - 0.00023 20.7 0.0 0.28 10.7 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_17 PF13207.6 AJA91966.1 - 0.00035 21.0 0.1 1.4 9.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 AJA91966.1 - 0.001 18.3 0.0 0.64 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 AJA91966.1 - 0.0014 18.3 0.0 1.7 8.3 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 AJA91966.1 - 0.0017 17.9 0.3 3.7 7.0 0.0 3.4 3 0 0 3 3 3 1 PhoH-like protein UFD1 PF03152.14 AJA91966.1 - 0.0022 17.5 0.1 0.011 15.2 0.2 1.9 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 Parvo_NS1 PF01057.17 AJA91966.1 - 0.0025 16.9 0.0 1.8 7.6 0.1 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 SRPRB PF09439.10 AJA91966.1 - 0.003 17.0 0.0 2 7.8 0.0 3.2 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_3 PF07726.11 AJA91966.1 - 0.0045 16.8 0.0 2.8 7.8 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 AJA91966.1 - 0.0048 16.1 0.1 2.1 7.5 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain KAP_NTPase PF07693.14 AJA91966.1 - 0.005 16.1 0.2 7.1 5.8 0.0 3.4 2 2 1 3 3 3 0 KAP family P-loop domain AAA_11 PF13086.6 AJA91966.1 - 0.0058 16.5 0.0 2.6 7.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain Vps4_C PF09336.10 AJA91966.1 - 0.013 15.5 0.1 1.8 8.6 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Adeno_IVa2 PF02456.15 AJA91966.1 - 0.017 13.9 0.2 6.2 5.5 0.0 2.6 3 0 0 3 3 3 0 Adenovirus IVa2 protein DUF2075 PF09848.9 AJA91966.1 - 0.05 12.8 0.0 2.2 7.4 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.9 AJA91966.1 - 0.053 13.3 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 AJA91966.1 - 0.23 11.8 0.8 28 5.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain tRNA-synt_His PF13393.6 AJA91968.1 - 7.3e-42 143.7 0.0 9.6e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 AJA91968.1 - 7.8e-12 45.5 5.3 2e-11 44.2 5.3 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AJA91968.1 - 8e-10 38.7 0.4 1.7e-09 37.7 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 AJA91968.1 - 0.0005 19.6 0.0 0.00085 18.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Ground-like PF04155.18 AJA91968.1 - 0.66 10.7 2.6 1.2 9.9 0.1 2.6 3 0 0 3 3 3 0 Ground-like domain TPR_2 PF07719.17 AJA91969.1 - 1.3e-06 28.0 0.6 5.8e-06 26.0 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 AJA91969.1 - 4e-06 26.4 3.4 1.6e-05 24.5 0.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 AJA91969.1 - 1.4e-05 24.9 0.4 1.4e-05 24.9 0.4 1.9 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 AJA91969.1 - 7.3e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Peptidase_M54 PF07998.11 AJA91969.1 - 8.8e-05 22.6 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_3 PF13582.6 AJA91969.1 - 0.00022 21.8 0.0 0.00051 20.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 AJA91969.1 - 0.00093 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 AJA91969.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 AJA91969.1 - 0.0018 17.3 0.4 0.0057 15.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase M66 Zincin_1 PF06262.11 AJA91969.1 - 0.0042 17.2 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 Zincin-like metallopeptidase TPR_11 PF13414.6 AJA91969.1 - 0.007 16.0 0.9 0.98 9.2 0.3 2.5 2 0 0 2 2 2 1 TPR repeat Reprolysin_2 PF13574.6 AJA91969.1 - 0.0071 16.3 0.1 0.021 14.8 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like DUF3744 PF12558.8 AJA91969.1 - 0.0078 17.0 0.2 0.019 15.7 0.2 1.6 1 0 0 1 1 1 1 ATP-binding cassette cobalt transporter Metallopep PF12044.8 AJA91969.1 - 0.019 13.6 0.1 0.1 11.2 0.0 1.9 2 0 0 2 2 2 0 Putative peptidase family Peptidase_M10 PF00413.24 AJA91969.1 - 0.04 13.8 0.1 0.096 12.5 0.1 1.8 1 1 0 1 1 1 0 Matrixin TPR_6 PF13174.6 AJA91969.1 - 0.067 13.9 0.1 0.29 11.9 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 AJA91969.1 - 0.14 12.0 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat OTCace_N PF02729.21 AJA91970.1 - 8e-53 178.4 0.0 1.3e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AJA91970.1 - 9.8e-51 171.9 0.3 1.6e-50 171.2 0.3 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain TctA PF01970.16 AJA91971.1 - 0.027 13.2 2.9 0.036 12.8 2.9 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family GTP-bdg_N PF13167.6 AJA91972.1 - 4.3e-17 62.6 0.7 1.1e-16 61.3 0.7 1.7 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 AJA91972.1 - 1e-15 57.8 1.4 1.5e-15 57.2 0.2 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_M PF16360.5 AJA91972.1 - 4.8e-15 55.9 3.9 4.8e-15 55.9 3.9 2.2 2 0 0 2 2 2 1 GTP-binding GTPase Middle Region RsgA_GTPase PF03193.16 AJA91972.1 - 9.7e-06 25.6 8.9 0.0017 18.3 0.2 3.0 3 0 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 AJA91972.1 - 2.8e-05 23.7 0.7 2.8e-05 23.7 0.7 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 AJA91972.1 - 0.0019 17.6 3.3 0.006 16.1 3.3 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 AJA91972.1 - 0.0035 16.8 1.3 0.008 15.6 1.3 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 AJA91972.1 - 0.0036 17.8 0.8 0.014 16.0 0.1 2.1 2 1 0 2 2 2 1 ABC transporter PduV-EutP PF10662.9 AJA91972.1 - 0.0038 17.0 2.4 0.11 12.3 2.4 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 AJA91972.1 - 0.0046 17.4 2.3 0.062 13.7 0.2 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 AJA91972.1 - 0.023 14.7 0.2 0.069 13.2 0.0 2.0 2 0 0 2 2 2 0 Dynamin family CHASE2 PF05226.11 AJA91972.1 - 0.042 13.5 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 CHASE2 domain DUF4200 PF13863.6 AJA91972.1 - 0.061 13.7 4.3 0.24 11.8 4.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) cobW PF02492.19 AJA91972.1 - 0.17 11.4 4.3 1.1 8.8 0.2 2.9 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 AJA91972.1 - 0.25 10.9 5.1 2.2 7.8 1.9 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 AJA91972.1 - 2.8 8.0 10.1 14 5.7 0.5 3.4 2 1 1 3 3 3 0 AAA domain TPR_1 PF00515.28 AJA91973.1 - 3.6e-16 58.2 10.8 4.5e-06 26.2 0.4 4.7 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 AJA91973.1 - 3e-12 45.6 6.5 0.0005 20.0 0.3 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 AJA91973.1 - 5.3e-09 35.8 10.8 0.00065 19.9 0.2 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 AJA91973.1 - 4e-08 32.8 5.2 0.051 13.8 0.1 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 AJA91973.1 - 4.9e-07 29.9 0.1 0.00042 20.5 0.1 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 AJA91973.1 - 7.3e-06 25.6 8.9 0.035 13.8 0.0 4.0 2 1 2 4 4 4 3 TPR repeat TPR_9 PF13371.6 AJA91973.1 - 6.2e-05 23.1 0.0 0.00028 21.0 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Peptidase_C39_2 PF13529.6 AJA91973.1 - 0.0003 21.4 0.0 0.0026 18.3 0.0 2.3 1 1 0 1 1 1 1 Peptidase_C39 like family TPR_14 PF13428.6 AJA91973.1 - 0.00046 20.8 0.0 4.2 8.4 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AJA91973.1 - 0.0026 18.3 0.9 1.9 9.0 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AJA91973.1 - 0.0048 16.8 0.8 0.22 11.7 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 AJA91973.1 - 0.0074 16.9 0.0 8.1 7.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 AJA91973.1 - 0.011 15.6 0.2 0.63 10.0 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Peptidase_C70 PF12385.8 AJA91973.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Beta-Casp PF10996.8 AJA91974.1 - 6.4e-24 84.4 0.0 1.2e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain KH_7 PF17214.3 AJA91974.1 - 9.7e-21 73.5 1.1 2.3e-20 72.3 1.1 1.7 1 0 0 1 1 1 1 KH domain RMMBL PF07521.12 AJA91974.1 - 8.3e-14 51.3 0.0 2.1e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 AJA91974.1 - 5.2e-13 48.9 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 AJA91974.1 - 6e-13 49.2 0.4 1.4e-11 44.7 0.4 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AJA91974.1 - 3.6e-11 43.0 0.0 1e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AJA91974.1 - 0.0028 17.6 0.0 0.018 15.0 0.1 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Aminotran_3 PF00202.21 AJA91975.1 - 2.7e-71 240.4 0.0 3.6e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AJA91975.1 - 9.3e-07 28.3 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF86 PF01934.17 AJA91976.1 - 0.022 14.6 0.3 0.035 14.0 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF86 ENTH PF01417.20 AJA91976.1 - 0.026 14.6 0.5 0.1 12.7 0.5 1.8 1 1 0 1 1 1 0 ENTH domain DUF4145 PF13643.6 AJA91976.1 - 0.048 13.8 0.3 0.077 13.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) 7tm_1 PF00001.21 AJA91978.1 - 0.053 12.8 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DNA_pol3_delta PF06144.13 AJA91980.1 - 0.018 14.9 0.1 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit PetG PF02529.15 AJA91981.1 - 0.054 13.3 0.2 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF108 PF01958.18 AJA91982.1 - 6.2e-32 109.8 0.1 1.4e-31 108.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 AJA91982.1 - 1.4e-14 54.7 0.1 2.5e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 AJA91982.1 - 0.00011 22.3 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 AJA91982.1 - 0.012 16.4 0.0 0.051 14.4 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 AJA91982.1 - 0.024 15.2 0.1 0.06 13.9 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 AJA91982.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PIG-L PF02585.17 AJA91983.1 - 1.8e-30 106.2 0.0 2.4e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase QueC PF06508.13 AJA91983.1 - 0.033 13.7 0.1 0.094 12.2 0.0 1.8 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC Glyco_trans_4_2 PF13477.6 AJA91983.1 - 0.053 13.5 0.5 0.55 10.3 0.1 2.2 1 1 1 2 2 2 0 Glycosyl transferase 4-like DUF3782 PF12644.7 AJA91983.1 - 0.22 11.7 0.6 2.8 8.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) SpoIISA_toxin PF14171.6 AJA91983.1 - 0.27 10.9 4.4 0.44 10.2 4.4 1.4 1 1 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system HTH_Crp_2 PF13545.6 AJA91985.1 - 0.00022 21.1 0.1 0.00052 19.9 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 AJA91985.1 - 0.00031 20.6 0.0 0.00072 19.4 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 AJA91985.1 - 0.0049 17.3 0.1 0.0079 16.7 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AJA91985.1 - 0.0074 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 MarR family DUF4330 PF14221.6 AJA91985.1 - 0.027 14.7 0.8 0.05 13.8 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4330) HTH_12 PF08461.10 AJA91985.1 - 0.041 13.8 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain MadM PF03818.13 AJA91985.1 - 0.084 12.8 1.3 0.15 11.9 1.3 1.4 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit Crp PF00325.20 AJA91985.1 - 0.091 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_20 PF12840.7 AJA91985.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain S10_plectin PF03501.15 AJA91985.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain MG2 PF01835.19 AJA91987.1 - 1.8e-18 66.7 0.0 4e-05 24.0 0.0 5.2 4 1 1 5 5 5 3 MG2 domain FlgD_ig PF13860.6 AJA91987.1 - 1.5e-06 27.9 6.6 0.45 10.4 0.0 6.3 6 0 0 6 6 6 3 FlgD Ig-like domain Gmad2 PF10648.9 AJA91987.1 - 0.00018 21.7 1.1 1.2 9.4 0.0 5.2 5 1 0 5 5 5 1 Immunoglobulin-like domain of bacterial spore germination Big_6 PF17936.1 AJA91987.1 - 0.00043 20.5 7.8 0.35 11.2 0.1 5.6 4 2 1 6 6 6 2 Bacterial Ig domain Big_1 PF02369.16 AJA91987.1 - 1.1 9.3 6.1 7.2 6.7 0.2 5.1 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 1) ABC_tran PF00005.27 AJA91988.1 - 7.4e-35 120.4 0.1 1.2e-34 119.7 0.1 1.4 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AJA91988.1 - 4.5e-05 23.9 0.0 0.00013 22.4 0.0 1.8 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region G-alpha PF00503.20 AJA91988.1 - 6.6e-05 22.2 0.9 8.5e-05 21.9 0.9 1.1 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.6 AJA91988.1 - 7.5e-05 23.2 0.0 0.00011 22.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AJA91988.1 - 9.3e-05 22.0 1.6 0.00019 21.0 1.6 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AJA91988.1 - 0.00012 22.3 0.9 0.0013 19.0 0.9 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AJA91988.1 - 0.00013 22.0 0.1 0.00031 20.7 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 AJA91988.1 - 0.00026 20.9 0.2 0.39 10.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AJA91988.1 - 0.00055 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 AJA91988.1 - 0.00089 18.0 1.8 0.076 11.7 0.2 2.1 1 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 AJA91988.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.17 AJA91988.1 - 0.0021 18.2 1.0 0.0051 16.9 0.4 2.0 1 1 1 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 AJA91988.1 - 0.0091 15.1 0.1 0.02 13.9 0.0 1.7 1 1 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.22 AJA91988.1 - 0.018 14.2 0.3 0.055 12.7 0.1 1.8 1 1 1 2 2 2 0 NB-ARC domain PRK PF00485.18 AJA91988.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 AJA91988.1 - 0.025 15.0 0.2 0.15 12.4 0.2 2.4 1 1 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 AJA91988.1 - 0.026 14.4 0.1 0.29 11.0 0.0 2.5 2 1 1 3 3 3 0 Adenylylsulphate kinase TniB PF05621.11 AJA91988.1 - 0.026 13.9 1.9 1.3 8.4 0.2 2.9 3 0 0 3 3 3 0 Bacterial TniB protein AAA_18 PF13238.6 AJA91988.1 - 0.043 14.4 0.1 0.19 12.3 0.1 2.0 1 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AJA91988.1 - 0.046 14.2 3.0 0.095 13.2 3.0 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 AJA91988.1 - 0.059 13.1 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF3987 PF13148.6 AJA91988.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_30 PF13604.6 AJA91988.1 - 0.089 12.5 0.2 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AJA91988.1 - 0.091 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 AJA91988.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) z-alpha PF02295.17 AJA91988.1 - 0.14 12.2 1.0 9.1 6.4 0.1 2.4 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain NTPase_1 PF03266.15 AJA91988.1 - 0.2 11.6 2.7 0.59 10.0 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA PF00004.29 AJA91988.1 - 0.21 12.0 3.4 2.5 8.5 3.4 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-synt_D PF01813.17 AJA91989.1 - 2.6e-45 154.7 4.0 3e-45 154.5 4.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit D PerC PF06069.11 AJA91989.1 - 0.013 15.7 0.4 0.053 13.8 0.0 2.2 2 1 1 3 3 3 0 PerC transcriptional activator Peptidase_M3_N PF08439.10 AJA91989.1 - 0.048 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Oligopeptidase F TFIIS_M PF07500.14 AJA91989.1 - 0.074 13.5 1.9 0.19 12.3 0.9 2.0 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain RNA_binding PF01877.17 AJA91989.1 - 0.22 11.8 4.8 2.1 8.6 0.7 2.2 2 0 0 2 2 2 0 RNA binding ATP-grasp PF02222.22 AJA91990.1 - 4.7e-61 205.3 0.3 8e-61 204.6 0.3 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 AJA91990.1 - 2.5e-13 49.5 0.1 5.3e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AJA91990.1 - 2.7e-08 33.6 0.7 7.7e-08 32.1 0.7 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 AJA91990.1 - 2.7e-05 23.8 0.3 5.5e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 AJA91990.1 - 3.5e-05 23.5 1.1 6.3e-05 22.6 0.8 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 AJA91990.1 - 0.00017 21.7 0.6 0.00032 20.8 0.6 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 AJA91990.1 - 0.00061 19.6 0.3 0.0013 18.5 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF1297 PF06973.12 AJA91990.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) TrkA_N PF02254.18 AJA91990.1 - 0.049 13.9 0.6 0.29 11.4 0.0 2.6 3 1 0 3 3 3 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 AJA91990.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PEP-utilizers_C PF02896.18 AJA91991.1 - 4e-83 278.9 0.2 7.9e-83 277.9 0.2 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 AJA91991.1 - 1.3e-55 189.0 0.3 2.6e-32 112.4 0.0 3.7 2 1 2 4 4 4 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 AJA91991.1 - 2.2e-23 81.8 0.1 6.4e-23 80.3 0.1 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain DUF968 PF06147.11 AJA91991.1 - 0.029 14.6 0.1 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF968) PEARLI-4 PF05278.12 AJA91991.1 - 0.041 13.5 0.3 0.041 13.5 0.3 2.5 3 0 0 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) EF-hand_12 PF17901.1 AJA91991.1 - 0.13 12.8 0.0 0.69 10.4 0.0 2.2 2 0 0 2 2 2 0 EF-hand fold domain GCR1_C PF12550.8 AJA91991.1 - 0.19 12.0 4.3 8.7 6.7 0.0 4.2 4 0 0 4 4 4 0 Transcriptional activator of glycolytic enzymes TGT PF01702.18 AJA91993.1 - 9.3e-64 215.8 0.0 1.3e-63 215.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF5591 PF17884.1 AJA91993.1 - 6.1e-10 39.2 1.2 1.3e-09 38.1 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5591) Ribosomal_S2 PF00318.20 AJA91994.1 - 2.2e-21 76.1 0.1 6.6e-12 45.1 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein S2 RecR PF02132.15 AJA91995.1 - 0.026 14.1 0.3 0.052 13.1 0.3 1.6 1 0 0 1 1 1 0 RecR protein TFIIS_C PF01096.18 AJA91996.1 - 3.1e-18 65.3 6.4 3.1e-18 65.3 6.4 2.9 2 1 1 3 3 3 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 AJA91996.1 - 0.0054 16.6 8.8 0.17 11.8 5.7 3.0 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit OrfB_Zn_ribbon PF07282.11 AJA91996.1 - 0.012 15.5 1.8 0.012 15.5 1.8 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_4 PF13717.6 AJA91996.1 - 0.027 14.4 1.4 0.027 14.4 1.4 3.7 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 AJA91996.1 - 0.029 14.4 1.4 0.029 14.4 1.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf_C2H2_10 PF18414.1 AJA91996.1 - 0.079 12.5 0.3 0.079 12.5 0.3 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger Zn_ribbon_17 PF17120.5 AJA91996.1 - 0.11 12.1 3.7 4.4 7.0 0.8 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C4pol PF14260.6 AJA91996.1 - 0.12 12.8 5.7 0.082 13.4 2.3 2.2 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta IBR PF01485.21 AJA91996.1 - 0.12 12.6 11.8 0.16 12.2 2.3 2.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-TFIIB PF13453.6 AJA91996.1 - 0.35 10.2 7.1 5.4 6.4 3.6 3.0 2 1 1 3 3 3 0 Transcription factor zinc-finger Baculo_LEF5_C PF11792.8 AJA91996.1 - 0.41 10.4 4.4 0.31 10.7 0.6 2.3 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-C3HC4_4 PF15227.6 AJA91996.1 - 0.61 10.3 10.7 0.16 12.1 1.8 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Nudix_N_2 PF14803.6 AJA91996.1 - 1.6 8.7 6.9 49 4.0 3.7 3.1 2 1 0 2 2 2 0 Nudix N-terminal zinc_ribbon_10 PF10058.9 AJA91996.1 - 2.4 7.9 8.9 9.1 6.1 2.3 2.7 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Auto_anti-p27 PF06677.12 AJA91996.1 - 3.8 7.7 7.6 0.78 9.9 3.2 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) C1_4 PF07975.12 AJA91996.1 - 4.5 7.6 14.5 3.3 8.0 1.6 3.5 2 2 1 3 3 3 0 TFIIH C1-like domain HypA PF01155.19 AJA91996.1 - 4.9 7.2 8.4 1.6 8.7 1.0 2.3 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 AJA91996.1 - 5.1 7.1 13.6 7.3 6.7 3.2 3.0 2 2 1 3 3 3 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AJA91996.1 - 6.4 6.4 14.2 1.6 8.3 4.5 3.1 2 2 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 AJA91996.1 - 6.5 6.3 10.0 4.1 7.0 0.1 3.4 4 0 0 4 4 4 0 zinc-ribbon domain Asn_synthase PF00733.21 AJA91997.1 - 9.3e-34 117.6 0.0 1.2e-33 117.3 0.0 1.0 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 AJA91997.1 - 2.4e-07 30.1 0.1 4.7e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 AJA91997.1 - 0.00025 20.9 0.0 0.00043 20.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 AJA91997.1 - 0.0014 17.5 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 AJA91997.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Peptidase_M50 PF02163.22 AJA91998.1 - 8.2e-12 44.9 15.4 6.4e-07 28.9 0.6 2.8 1 1 1 2 2 2 2 Peptidase family M50 DUF5056 PF16479.5 AJA91998.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) DUF3698 PF12479.8 AJA91998.1 - 0.12 12.9 0.1 0.21 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) DUF371 PF04027.13 AJA91999.1 - 3.5e-44 150.0 0.1 3.9e-44 149.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF371) Sua5_yciO_yrdC PF01300.18 AJA92000.1 - 2.3e-43 147.8 0.0 2.6e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination CPSase_L_D2 PF02786.17 AJA92001.1 - 1.3e-69 233.9 0.1 2e-69 233.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AJA92001.1 - 7.1e-46 155.3 0.0 1.3e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AJA92001.1 - 1.6e-33 115.1 0.0 3.2e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.22 AJA92001.1 - 4.9e-11 42.5 0.1 1.2e-10 41.3 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AJA92001.1 - 3.6e-09 36.5 0.2 1.1e-08 34.9 0.2 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AJA92001.1 - 8e-08 32.5 0.1 2e-07 31.2 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 AJA92001.1 - 1.5e-07 31.2 0.0 7.6e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 AJA92001.1 - 0.00022 20.9 0.1 0.00042 19.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AJA92001.1 - 0.027 13.7 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 AJA92001.1 - 0.045 13.5 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF3182 PF11379.8 AJA92001.1 - 0.051 12.5 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) GARS_A PF01071.19 AJA92001.1 - 0.098 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GNAT_acetyltran PF12746.7 AJA92002.1 - 0.006 16.2 0.2 0.0066 16.0 0.2 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase FISNA PF14484.6 AJA92002.1 - 0.067 13.4 0.5 0.098 12.9 0.5 1.2 1 0 0 1 1 1 0 Fish-specific NACHT associated domain DUF4330 PF14221.6 AJA92002.1 - 0.22 11.7 1.1 0.7 10.1 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4330) MM_CoA_mutase PF01642.22 AJA92003.1 - 5e-215 714.9 0.9 5.7e-215 714.7 0.9 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase Met_asp_mut_E PF06368.11 AJA92003.1 - 0.038 12.5 0.3 0.056 11.9 0.3 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) HigB_toxin PF09907.9 AJA92003.1 - 0.081 13.2 0.0 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system DUF2628 PF10947.8 AJA92004.1 - 0.017 15.4 2.5 0.02 15.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Glycophorin_A PF01102.18 AJA92004.1 - 0.042 14.1 0.0 0.049 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycophorin A Phage_holin_3_6 PF07332.11 AJA92004.1 - 0.064 13.3 3.4 0.075 13.1 3.4 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2427 PF10348.9 AJA92004.1 - 0.13 12.0 3.0 0.15 11.9 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF3149 PF11346.8 AJA92004.1 - 7.1 6.3 12.5 5.8 6.6 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Hydantoinase_A PF01968.18 AJA92005.1 - 1.6e-57 195.0 4.2 1.6e-57 195.0 4.2 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 AJA92005.1 - 3.2e-20 72.6 8.2 5e-19 68.7 4.5 2.8 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 AJA92005.1 - 1.6e-05 23.7 3.2 0.0029 16.3 0.5 2.3 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 AJA92005.1 - 0.00012 21.7 5.5 0.0031 17.0 1.7 2.9 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 AJA92005.1 - 0.00061 19.4 0.7 0.0023 17.6 0.7 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain GHMP_kinases_C PF08544.13 AJA92005.1 - 0.035 14.5 0.1 0.48 10.8 0.0 2.8 3 0 0 3 3 3 0 GHMP kinases C terminal CbiD PF01888.17 AJA92007.1 - 1.5e-90 302.9 4.2 2.3e-90 302.3 4.2 1.3 1 0 0 1 1 1 1 CbiD Ret2_MD PF18528.1 AJA92007.1 - 0.033 14.5 0.1 0.84 10.1 0.1 2.7 2 0 0 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain DUF3042 PF11240.8 AJA92007.1 - 0.061 13.3 2.2 0.29 11.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) RNase_PH PF01138.21 AJA92008.1 - 1e-36 126.3 0.0 1.4e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AJA92008.1 - 8.1e-13 48.2 0.1 1.8e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Kazal_3 PF18434.1 AJA92008.1 - 0.15 11.8 0.5 3.1 7.6 0.0 2.9 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain Arginase PF00491.21 AJA92009.1 - 1.7e-69 234.5 0.0 2.1e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family Ferritin PF00210.24 AJA92010.1 - 3.3e-19 69.2 4.1 4.2e-19 68.9 4.1 1.0 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.6 AJA92010.1 - 0.00037 20.7 0.7 0.00049 20.3 0.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 AJA92010.1 - 0.00067 20.1 5.4 0.0037 17.7 5.4 1.9 1 1 0 1 1 1 1 Rubrerythrin DUF4352 PF11611.8 AJA92011.1 - 0.07 13.4 0.0 0.32 11.3 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4352) GATase_3 PF07685.14 AJA92013.1 - 1.5e-43 148.7 0.0 2.2e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AJA92013.1 - 3e-19 69.4 0.2 1.5e-17 63.9 0.1 2.7 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AJA92013.1 - 6.5e-16 58.7 2.3 1.1e-09 38.4 0.0 3.4 3 1 1 4 4 4 2 AAA domain CTP_synth_N PF06418.14 AJA92013.1 - 0.011 15.0 0.1 0.025 13.9 0.1 1.5 1 0 0 1 1 1 0 CTP synthase N-terminus Fer4_NifH PF00142.18 AJA92013.1 - 0.02 14.4 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 AJA92013.1 - 0.082 12.5 0.8 0.28 10.8 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MobB PF03205.14 AJA92013.1 - 0.11 12.4 0.1 0.55 10.1 0.0 2.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Glycos_transf_1 PF00534.20 AJA92014.1 - 4.9e-27 94.5 0.3 1.6e-24 86.4 0.1 2.2 1 1 1 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AJA92014.1 - 1.7e-18 67.3 0.0 2.9e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AJA92014.1 - 2e-11 44.1 0.0 2.4e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AJA92014.1 - 6.6e-10 39.3 0.1 2.8e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AJA92014.1 - 5.1e-06 27.0 0.0 0.0032 17.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AJA92014.1 - 0.0012 18.9 0.1 0.0024 17.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Epimerase_2 PF02350.19 AJA92014.1 - 0.0071 15.2 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase eIF-6 PF01912.18 AJA92014.1 - 0.0079 15.6 0.6 0.033 13.6 0.2 1.8 1 1 0 1 1 1 1 eIF-6 family Helicase_IV_N PF12462.8 AJA92014.1 - 0.037 14.0 0.2 0.075 13.0 0.1 1.5 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal DUF4364 PF14277.6 AJA92015.1 - 0.0024 17.7 0.2 0.0037 17.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_45 PF14947.6 AJA92015.1 - 0.0041 17.1 0.4 0.0063 16.5 0.4 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix NAD_binding_8 PF13450.6 AJA92016.1 - 0.00011 22.4 0.7 0.00056 20.1 0.2 2.4 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AJA92016.1 - 0.00024 20.5 0.1 0.11 11.7 0.2 2.6 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 AJA92016.1 - 0.00058 19.2 0.2 0.9 8.7 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJA92016.1 - 0.00077 20.0 1.5 1.1 9.9 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Ntox1 PF15500.6 AJA92016.1 - 0.0013 19.0 0.2 0.0071 16.7 0.0 2.2 2 1 0 2 2 2 1 Putative RNase-like toxin, toxin_1 FAD_binding_2 PF00890.24 AJA92016.1 - 0.0019 17.4 0.8 0.0033 16.6 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AJA92016.1 - 0.0019 17.6 0.2 0.0076 15.6 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 AJA92016.1 - 0.003 17.2 1.3 0.034 13.7 0.9 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 AJA92016.1 - 0.0041 16.4 1.0 0.01 15.1 0.2 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 AJA92016.1 - 0.0095 14.7 0.1 0.02 13.6 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 AJA92016.1 - 0.023 13.8 0.0 2.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 AJA92016.1 - 0.039 12.8 0.9 3 6.6 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase SWI2_SNF2 PF18766.1 AJA92016.1 - 0.087 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Amino_oxidase PF01593.24 AJA92016.1 - 0.13 11.5 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase PALP PF00291.25 AJA92017.1 - 2.6e-47 161.7 0.0 3.9e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-ribbon_3 PF13248.6 AJA92017.1 - 0.37 10.3 1.8 0.43 10.1 0.4 1.9 2 0 0 2 2 2 0 zinc-ribbon domain ABC_tran PF00005.27 AJA92018.1 - 1.1e-27 97.2 0.0 2.5e-27 96.0 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AJA92018.1 - 1.8e-14 54.2 0.1 6.2e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AJA92018.1 - 8.5e-06 25.4 0.3 0.0095 15.4 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AJA92018.1 - 2.2e-05 25.1 2.4 6.3e-05 23.6 2.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AJA92018.1 - 0.00036 20.4 0.4 0.042 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 AJA92018.1 - 0.0004 20.8 0.4 0.43 11.0 0.1 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AJA92018.1 - 0.0021 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain TniB PF05621.11 AJA92018.1 - 0.0048 16.3 0.1 0.28 10.6 0.1 2.2 2 0 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 AJA92018.1 - 0.0057 16.4 0.1 0.77 9.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_27 PF13514.6 AJA92018.1 - 0.0057 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AJA92018.1 - 0.018 15.1 0.4 0.038 14.1 0.4 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 AJA92018.1 - 0.04 13.1 0.3 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 AJA92018.1 - 0.051 13.8 0.1 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AJA92018.1 - 0.068 13.4 0.0 3 8.2 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 AJA92018.1 - 0.09 12.8 0.2 6.9 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 AJA92018.1 - 0.14 11.8 0.1 0.14 11.8 0.1 1.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 AJA92018.1 - 0.15 12.5 0.0 0.68 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 AJA92018.1 - 0.4 9.2 5.8 0.65 8.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain Tautomerase PF01361.21 AJA92020.1 - 4.2e-18 65.0 0.1 4.4e-18 64.9 0.1 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.6 AJA92020.1 - 2.4e-09 37.2 0.0 2.5e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_3 PF14832.6 AJA92020.1 - 0.049 13.9 0.0 0.049 13.9 0.0 1.0 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme AsnC_trans_reg2 PF17805.1 AJA92021.1 - 3.2e-53 177.8 0.0 5.9e-30 103.3 0.0 2.7 3 0 0 3 3 3 2 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AJA92021.1 - 7.5e-10 38.5 0.0 4.4e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AJA92021.1 - 2e-05 24.1 0.4 0.0012 18.3 0.3 3.1 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AJA92021.1 - 0.0072 15.8 0.0 0.19 11.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 AsnC_trans_reg PF01037.21 AJA92021.1 - 0.023 14.7 0.0 7.1 6.7 0.0 3.3 2 1 0 2 2 2 0 Lrp/AsnC ligand binding domain LexA_DNA_bind PF01726.16 AJA92021.1 - 0.025 14.4 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 LexA DNA binding domain HTH_10 PF04967.12 AJA92021.1 - 0.044 13.6 0.0 4.9 7.0 0.0 2.7 2 0 0 2 2 2 0 HTH DNA binding domain DUF2250 PF10007.9 AJA92021.1 - 0.048 13.8 0.0 14 5.8 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DUF3791 PF12668.7 AJA92021.1 - 0.049 13.7 0.0 5.9 7.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) Sigma70_r4_2 PF08281.12 AJA92021.1 - 0.059 13.1 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 FeoC PF09012.10 AJA92021.1 - 0.075 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_Tnp_ISL3 PF13542.6 AJA92021.1 - 0.085 12.3 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 IF2_N PF04760.15 AJA92021.1 - 0.12 12.2 0.9 18 5.2 0.0 3.3 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Hexapep PF00132.24 AJA92022.1 - 1.7e-08 33.8 9.9 0.00012 21.7 4.6 3.8 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AJA92022.1 - 5.5e-07 29.2 6.7 0.005 16.6 4.7 3.6 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 AJA92023.1 - 1.1e-13 51.1 0.6 1.3e-13 50.9 0.6 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 AJA92023.1 - 2.1e-09 37.1 0.2 1.3e-07 31.2 0.2 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 AJA92023.1 - 9.5e-07 28.4 0.1 1.8e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 AJA92023.1 - 2.9e-06 27.0 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 AJA92023.1 - 2.7e-05 24.2 0.0 0.029 14.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.11 AJA92023.1 - 0.00014 21.6 0.7 0.00018 21.2 0.7 1.4 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 AJA92023.1 - 0.0032 16.3 0.1 0.0036 16.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 AJA92023.1 - 0.0069 15.7 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 AJA92023.1 - 0.032 13.8 0.1 0.078 12.6 0.1 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase Kinase-PolyVal PF18762.1 AJA92023.1 - 0.035 14.1 0.5 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins EcKinase PF02958.20 AJA92023.1 - 0.1 11.9 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase CxxCxxCC PF03692.15 AJA92024.1 - 8.2e-09 36.0 0.0 1.8e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain NUDIX PF00293.28 AJA92025.1 - 6.1e-13 48.9 0.0 8.6e-13 48.5 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain Ribosomal_S10 PF00338.22 AJA92026.1 - 3.4e-22 78.5 0.0 3.8e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CTX_RstB PF07459.11 AJA92026.1 - 0.14 12.4 0.0 0.19 12.0 0.0 1.1 1 0 0 1 1 1 0 CTX phage RstB protein DHBP_synthase PF00926.19 AJA92027.1 - 3.7e-59 199.5 0.0 4.2e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PAF-AH_p_II PF03403.13 AJA92027.1 - 0.00077 18.1 0.1 0.0013 17.3 0.0 1.4 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II NAC PF01849.18 AJA92029.1 - 2e-14 53.3 4.5 9.3e-14 51.2 3.8 1.9 2 0 0 2 2 2 1 NAC domain UBA_4 PF14555.6 AJA92029.1 - 0.0071 16.1 0.6 0.011 15.6 0.6 1.3 1 0 0 1 1 1 1 UBA-like domain DMA PF03474.14 AJA92029.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 DMRTA motif ScdA_N PF04405.14 AJA92029.1 - 0.12 12.1 0.9 9.6 6.0 0.0 2.7 2 1 1 3 3 3 0 Domain of Unknown function (DUF542) UBA PF00627.31 AJA92029.1 - 0.43 10.6 0.2 0.43 10.6 0.2 2.1 2 0 0 2 2 2 0 UBA/TS-N domain Na_H_Exchanger PF00999.21 AJA92030.1 - 3.1e-54 184.2 54.6 4e-54 183.9 54.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Spore_YabQ PF09578.10 AJA92030.1 - 0.037 14.2 0.2 0.037 14.2 0.2 4.7 5 2 0 5 5 5 0 Spore cortex protein YabQ (Spore_YabQ) DUF655 PF04919.12 AJA92031.1 - 3.8e-45 154.0 0.9 4.3e-45 153.9 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_3 PF12836.7 AJA92031.1 - 0.0042 17.3 0.6 0.075 13.3 0.1 2.7 3 1 0 3 3 3 1 Helix-hairpin-helix motif Transposase_20 PF02371.16 AJA92031.1 - 0.0073 16.6 0.0 0.14 12.5 0.0 2.2 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family Formyl_trans_N PF00551.19 AJA92032.1 - 6.4e-12 45.6 0.0 8.2e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 AJA92032.1 - 0.015 15.6 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain tRNA_int_endo PF01974.17 AJA92033.1 - 7.6e-18 64.4 0.1 1.6e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 AJA92033.1 - 5e-12 45.3 0.6 2.9e-09 36.5 0.1 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Ribosomal_60s PF00428.19 AJA92034.1 - 1.5e-14 54.3 18.1 1.7e-14 54.1 18.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PPR_long PF17177.4 AJA92034.1 - 0.072 12.4 4.1 0.082 12.3 4.1 1.1 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Ribosomal_S28e PF01200.18 AJA92034.1 - 0.08 12.9 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein S28e CPBP PF02517.16 AJA92035.1 - 8.2e-15 54.9 5.0 8.2e-15 54.9 5.0 2.7 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease NAD_binding_7 PF13241.6 AJA92036.1 - 1.1e-16 61.2 0.2 6e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 AJA92036.1 - 0.00053 20.1 0.7 0.00053 20.1 0.7 2.1 1 1 2 3 3 3 1 Shikimate / quinate 5-dehydrogenase Sirohm_synth_M PF14824.6 AJA92036.1 - 0.0012 18.2 0.7 0.0027 17.1 0.7 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central TrkA_N PF02254.18 AJA92036.1 - 0.0043 17.3 0.1 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 AJA92036.1 - 0.0099 15.2 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AJA92036.1 - 0.036 13.6 0.4 0.064 12.8 0.1 1.6 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox PF00070.27 AJA92036.1 - 0.1 13.2 1.1 2.7 8.6 0.0 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 AJA92036.1 - 0.12 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Peripla_BP_1 PF00532.21 AJA92036.1 - 0.16 11.3 1.9 2.7 7.3 0.1 2.6 2 1 1 3 3 3 0 Periplasmic binding proteins and sugar binding domain of LacI family DUF3793 PF12672.7 AJA92036.1 - 1.5 8.9 6.2 0.77 9.8 1.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3793) Cupredoxin_1 PF13473.6 AJA92037.1 - 0.0003 20.9 0.0 0.00081 19.5 0.0 1.8 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 AJA92037.1 - 0.0066 16.9 0.0 0.026 15.0 0.0 2.0 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family TFIIB PF00382.19 AJA92038.1 - 2.7e-20 72.2 5.1 9.4e-11 41.6 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJA92038.1 - 3e-05 23.4 1.9 3.8e-05 23.1 0.3 1.9 2 0 0 2 2 2 1 TFIIB zinc-binding Rrf2 PF02082.20 AJA92038.1 - 8.7e-05 22.8 0.6 0.031 14.6 0.1 2.6 1 1 0 2 2 2 1 Transcriptional regulator RB_B PF01857.20 AJA92038.1 - 0.0026 17.8 0.2 0.059 13.4 0.1 2.2 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain HTH_IclR PF09339.10 AJA92038.1 - 0.0027 17.5 0.0 0.065 13.1 0.0 2.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AJA92038.1 - 0.0093 15.5 0.6 3.7 7.2 0.1 2.6 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_6 PF01418.17 AJA92038.1 - 0.011 15.6 0.8 0.34 10.9 0.5 3.0 2 1 1 3 3 3 0 Helix-turn-helix domain, rpiR family Cyclin_N PF00134.23 AJA92038.1 - 0.012 15.4 0.4 0.06 13.1 0.1 2.1 2 0 0 2 2 2 0 Cyclin, N-terminal domain MarR_2 PF12802.7 AJA92038.1 - 0.017 15.0 0.1 8 6.4 0.0 2.4 2 0 0 2 2 2 0 MarR family TrmB PF01978.19 AJA92038.1 - 0.021 14.7 0.2 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.16 AJA92038.1 - 0.028 13.9 0.0 5.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 AJA92038.1 - 0.038 14.0 0.1 9.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_3 PF01381.22 AJA92038.1 - 0.067 13.3 0.4 8 6.6 0.1 2.9 3 0 0 3 3 2 0 Helix-turn-helix HTH_37 PF13744.6 AJA92038.1 - 0.085 12.8 0.3 0.72 9.9 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.6 AJA92038.1 - 0.14 12.7 0.5 20 5.7 0.0 2.8 2 1 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HypA PF01155.19 AJA92038.1 - 0.18 11.9 2.3 5.2 7.1 0.3 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S27e PF01667.17 AJA92038.1 - 0.41 10.4 2.3 0.8 9.5 2.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 HTH_11 PF08279.12 AJA92038.1 - 0.98 9.4 4.6 1.3 9.0 0.1 3.3 5 0 0 5 5 5 0 HTH domain ATP-synt_C PF00137.21 AJA92039.1 - 8.1e-16 58.1 17.4 8.1e-16 58.1 17.4 1.9 2 0 0 2 2 2 1 ATP synthase subunit C Trypan_PARP PF05887.11 AJA92039.1 - 0.28 11.1 0.6 0.38 10.7 0.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) 2-Hacid_dh_C PF02826.19 AJA92040.1 - 2.1e-62 209.6 0.1 3.2e-62 209.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AJA92040.1 - 1.5e-31 108.8 0.0 1.7e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AJA92040.1 - 6.5e-09 36.1 0.1 1e-08 35.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 AJA92040.1 - 4e-05 23.3 0.5 9.7e-05 22.0 0.2 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 AJA92040.1 - 0.00093 19.7 0.0 0.002 18.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 AJA92040.1 - 0.027 14.6 0.8 0.044 13.8 0.1 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 AJA92040.1 - 0.046 13.0 0.0 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Gp_dh_N PF00044.24 AJA92040.1 - 0.052 13.9 2.4 0.13 12.6 2.4 1.8 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Ribosomal_S8 PF00410.19 AJA92041.1 - 8.2e-23 80.7 0.1 9.6e-23 80.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 ATP_bind_1 PF03029.17 AJA92042.1 - 1.5e-53 182.1 0.1 1.7e-53 181.9 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein DUF2075 PF09848.9 AJA92042.1 - 0.0029 16.9 0.1 0.0042 16.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 AJA92042.1 - 0.003 18.0 0.0 0.0068 16.8 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 AJA92042.1 - 0.0056 17.2 0.0 0.0083 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 AJA92042.1 - 0.011 15.2 0.4 1.5 8.4 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain SRP54 PF00448.22 AJA92042.1 - 0.076 12.6 0.4 2.4 7.8 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 AJA92042.1 - 0.079 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PduV-EutP PF10662.9 AJA92042.1 - 0.079 12.7 0.9 11 5.7 0.0 3.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 AJA92042.1 - 0.091 13.0 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AJA92042.1 - 0.091 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AJA92042.1 - 0.12 12.2 0.5 12 5.8 0.0 3.2 3 1 0 3 3 3 0 RsgA GTPase AAA_24 PF13479.6 AJA92042.1 - 0.13 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AJA92042.1 - 0.17 11.8 0.2 0.75 9.7 0.1 2.0 2 0 0 2 2 2 0 NTPase DNA_primase_S PF01896.19 AJA92043.1 - 1.8e-17 63.9 0.1 8.9e-17 61.7 0.1 2.0 1 1 0 1 1 1 1 DNA primase small subunit MutS_IV PF05190.18 AJA92043.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV zf-Dof PF02701.15 AJA92043.1 - 0.094 12.9 0.5 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Dof domain, zinc finger HypA PF01155.19 AJA92043.1 - 0.35 10.9 4.8 0.59 10.2 4.3 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 AJA92043.1 - 1.4 8.9 3.6 0.66 10.0 0.8 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_6 PF14599.6 AJA92043.1 - 7.2 6.7 10.8 7.2 6.7 4.6 2.7 1 1 1 2 2 2 0 Zinc-ribbon zf-ribbon_3 PF13248.6 AJA92043.1 - 8 6.0 8.3 1.1 8.8 3.5 2.1 2 0 0 2 2 2 0 zinc-ribbon domain ALS_ss_C PF10369.9 AJA92044.1 - 2.4e-22 78.9 5.4 2.5e-21 75.6 0.4 2.3 2 1 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.25 AJA92044.1 - 3.5e-16 58.7 0.1 7.6e-16 57.6 0.1 1.6 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.6 AJA92044.1 - 2.1e-14 53.1 0.1 5.1e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AJA92044.1 - 2.3e-06 28.1 1.1 4.5e-06 27.2 1.1 1.4 1 0 0 1 1 1 1 ACT domain NIL PF09383.10 AJA92044.1 - 0.0058 16.5 0.1 0.018 14.9 0.1 1.8 2 0 0 2 2 2 1 NIL domain ComR_TPR PF18710.1 AJA92044.1 - 0.017 14.7 2.0 0.021 14.4 2.0 1.2 1 0 0 1 1 1 0 ComR tetratricopeptide CppA_C PF14507.6 AJA92044.1 - 0.093 13.5 0.4 0.15 12.8 0.4 1.2 1 0 0 1 1 1 0 CppA C-terminal DUF35_N PF12172.8 AJA92046.1 - 0.0022 17.8 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) ING PF12998.7 AJA92047.1 - 0.19 12.3 5.2 1 10.0 5.2 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Peptidase_M22 PF00814.25 AJA92048.1 - 2.6e-78 263.5 0.0 3.1e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family ACT_7 PF13840.6 AJA92050.1 - 0.029 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 ACT domain Aminotran_5 PF00266.19 AJA92051.1 - 9.5e-62 209.1 0.0 1.1e-61 208.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AJA92051.1 - 0.00088 18.5 0.0 0.0018 17.5 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Sld5 PF05916.11 AJA92053.1 - 6.1e-07 29.9 1.4 7.9e-07 29.5 1.4 1.1 1 0 0 1 1 1 1 GINS complex protein FimH_man-bind PF09160.10 AJA92054.1 - 0.068 12.9 0.4 0.077 12.7 0.4 1.1 1 0 0 1 1 1 0 FimH, mannose binding H_PPase PF03030.16 AJA92055.1 - 3e-218 726.6 47.7 3.6e-218 726.4 47.7 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Rieske PF00355.26 AJA92056.1 - 3.3e-17 62.2 0.0 3.8e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AJA92056.1 - 1.4e-09 37.8 0.0 1.7e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain PhoU PF01895.19 AJA92057.1 - 5e-11 42.9 3.9 2.1e-10 40.9 1.7 2.4 2 0 0 2 2 2 1 PhoU domain MazE_antitoxin PF04014.18 AJA92057.1 - 7.5e-06 25.8 0.1 1.9e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin DUF2080 PF09853.9 AJA92057.1 - 0.083 12.6 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) NAD_kinase PF01513.21 AJA92058.1 - 2.8e-33 115.4 0.3 3.9e-33 114.9 0.3 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AJA92058.1 - 0.005 16.4 0.0 0.0086 15.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain IF-2B PF01008.17 AJA92059.1 - 1.8e-88 296.4 1.2 2.1e-88 296.2 1.2 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family CARDB PF07705.11 AJA92060.1 - 7.1e-05 23.0 2.8 0.068 13.4 0.0 2.3 2 0 0 2 2 2 2 CARDB Lectin_like PF18560.1 AJA92062.1 - 0.01 16.0 0.2 0.026 14.7 0.2 1.6 1 1 1 2 2 2 0 Lectin like domain Acetyltransf_10 PF13673.7 AJA92063.1 - 8.1e-15 54.9 0.1 9.2e-15 54.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AJA92063.1 - 6.7e-08 32.8 0.1 8.2e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 AJA92063.1 - 1.8e-06 28.6 0.1 4.4e-06 27.3 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AJA92063.1 - 2.9e-06 27.6 0.1 4.4e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AJA92063.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Nitrate_red_del PF02613.15 AJA92063.1 - 0.062 13.3 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Nitrate reductase delta subunit Rad50_zn_hook PF04423.14 AJA92064.1 - 0.00076 19.3 0.7 0.00093 19.0 0.7 1.1 1 0 0 1 1 1 1 Rad50 zinc hook motif Zn_ribbon_SprT PF17283.2 AJA92064.1 - 0.022 14.6 0.6 0.028 14.3 0.6 1.2 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zinc_ribbon_2 PF13240.6 AJA92064.1 - 0.023 14.4 0.3 0.023 14.4 0.3 1.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF530 PF04409.12 AJA92064.1 - 0.11 10.8 0.4 0.11 10.8 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF530) Hydrolase_3 PF08282.12 AJA92067.1 - 7.2e-10 39.0 1.9 1.4e-09 38.1 0.8 1.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AJA92067.1 - 8.3e-09 36.0 0.7 9.8e-06 26.0 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AJA92067.1 - 8.2e-05 22.7 0.2 0.0026 17.8 0.2 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AJA92067.1 - 0.024 14.7 1.8 0.024 14.7 0.5 1.6 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase HA1 PF18239.1 AJA92067.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Hemagglutinin I HAD PF12710.7 AJA92067.1 - 0.11 12.9 0.0 2.6 8.4 0.0 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GATase PF00117.28 AJA92068.1 - 8.6e-53 178.9 0.1 9.6e-53 178.8 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJA92068.1 - 2.7e-10 40.4 0.2 4.5e-10 39.7 0.2 1.4 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AJA92068.1 - 0.00022 21.1 0.2 0.00051 19.9 0.2 1.7 1 1 0 1 1 1 1 SNO glutamine amidotransferase family DJ-1_PfpI PF01965.24 AJA92068.1 - 0.074 12.9 0.1 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 DJ-1/PfpI family RNase_PH PF01138.21 AJA92069.1 - 8.5e-23 81.3 0.0 1.9e-22 80.2 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AJA92069.1 - 1.4e-15 57.1 0.2 3.2e-15 55.9 0.2 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 AsnC_trans_reg PF01037.21 AJA92070.1 - 1.7e-10 40.7 0.1 1.9e-10 40.6 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GHMP_kinases_N PF00288.26 AJA92071.1 - 7.2e-10 39.0 0.9 1.2e-09 38.3 0.2 1.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AJA92071.1 - 0.0083 16.5 0.0 0.022 15.1 0.0 1.8 1 1 0 1 1 1 1 GHMP kinases C terminal ArlS_N PF18719.1 AJA92071.1 - 0.078 13.2 1.1 3.2 8.0 0.0 2.2 2 0 0 2 2 2 0 ArlS sensor domain Trans_coact PF16805.5 AJA92071.1 - 0.089 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Phage late-transcription coactivator B12-binding PF02310.19 AJA92072.1 - 1.6e-10 41.0 0.0 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 AJA92072.1 - 1.4e-07 31.8 0.0 2.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain OKR_DC_1_N PF03709.15 AJA92072.1 - 0.12 12.6 0.0 0.95 9.8 0.0 2.1 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain SAC3 PF12209.8 AJA92072.1 - 1.9 8.8 5.5 5.2 7.3 0.7 3.4 3 1 0 3 3 3 0 Leucine permease transcriptional regulator helical domain PALP PF00291.25 AJA92073.1 - 2.5e-21 76.3 0.1 3.9e-20 72.5 0.0 2.7 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme SecY PF00344.20 AJA92074.1 - 3.2e-60 204.0 16.3 3.9e-60 203.7 16.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 AJA92074.1 - 8.3e-12 44.7 1.9 2.6e-11 43.2 0.6 2.6 2 0 0 2 2 2 1 Plug domain of Sec61p Phage_holin_5_1 PF06946.11 AJA92074.1 - 0.08 13.3 4.0 0.95 9.9 0.1 2.9 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 Biotin_lipoyl PF00364.22 AJA92075.1 - 1.5e-16 60.0 5.1 1.5e-16 60.0 5.1 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AJA92075.1 - 3.3e-12 46.0 11.4 2.9e-08 33.4 0.2 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AJA92075.1 - 2.4e-05 23.7 0.5 0.098 11.9 0.1 2.2 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AJA92075.1 - 5.5e-05 23.8 1.3 0.34 11.6 0.1 2.8 2 1 1 3 3 3 2 HlyD family secretion protein QRPTase_N PF02749.16 AJA92075.1 - 0.00026 21.0 1.7 0.092 12.8 0.1 3.0 2 1 1 3 3 3 2 Quinolinate phosphoribosyl transferase, N-terminal domain GCV_H PF01597.19 AJA92075.1 - 0.0019 18.1 1.7 0.0019 18.1 1.7 2.4 2 1 0 2 2 2 1 Glycine cleavage H-protein PASTA PF03793.19 AJA92075.1 - 0.011 15.6 6.4 0.16 11.8 0.4 3.2 3 1 0 3 3 3 0 PASTA domain DUF2118 PF09891.9 AJA92075.1 - 0.029 14.3 0.2 0.029 14.3 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) PCC_BT PF18140.1 AJA92075.1 - 0.032 14.6 1.0 0.11 12.9 0.2 2.2 1 1 1 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain DUF3114 PF11311.8 AJA92075.1 - 0.054 13.0 0.6 0.081 12.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) Peptidase_M23 PF01551.22 AJA92075.1 - 0.42 10.8 2.9 13 6.1 0.0 3.1 2 2 1 3 3 3 0 Peptidase family M23 TP_methylase PF00590.20 AJA92076.1 - 2.1e-16 60.5 0.0 3.4e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF357 PF04010.13 AJA92076.1 - 4.7e-15 55.4 0.5 2.2e-14 53.3 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF357) EFP PF01132.20 AJA92076.1 - 0.1 12.7 0.2 0.33 11.0 0.2 1.8 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain Ala_racemase_C PF00842.21 AJA92076.1 - 0.11 12.3 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 Alanine racemase, C-terminal domain Antirestrict PF03230.13 AJA92076.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Antirestriction protein GatB_N PF02934.15 AJA92077.1 - 1.1e-89 300.5 0.0 1.6e-89 299.9 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 AJA92077.1 - 4.2e-31 107.8 8.3 6.6e-31 107.2 8.3 1.3 1 0 0 1 1 1 1 GatB domain GATase PF00117.28 AJA92080.1 - 4.7e-43 147.2 0.0 7e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 AJA92080.1 - 8e-34 115.6 0.1 2.6e-33 113.9 0.1 1.9 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.17 AJA92080.1 - 4.1e-12 45.7 0.2 2.8e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 AJA92080.1 - 1.1e-07 31.8 0.1 4e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 AJA92080.1 - 0.00041 19.2 0.0 0.0023 16.8 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 AJA92080.1 - 0.0014 18.3 0.0 0.033 13.8 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 AJA92080.1 - 0.029 14.4 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 AJA92080.1 - 0.21 11.1 0.0 4.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC HD PF01966.22 AJA92081.1 - 1.6e-16 60.6 0.2 3.8e-16 59.4 0.2 1.7 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 AJA92081.1 - 0.0041 16.9 0.9 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 HD containing hydrolase-like enzyme PDEase_I PF00233.19 AJA92081.1 - 0.0069 16.1 0.0 0.04 13.6 0.0 2.0 1 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HDOD PF08668.12 AJA92081.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 HDOD domain PIN_8 PF18476.1 AJA92081.1 - 0.032 14.1 0.4 0.032 14.1 0.4 2.1 2 1 1 3 3 3 0 PIN like domain NusA_N PF08529.11 AJA92081.1 - 0.076 13.4 5.6 3.8 7.9 0.5 2.8 1 1 1 2 2 2 0 NusA N-terminal domain Zn-ribbon_8 PF09723.10 AJA92082.1 - 0.039 14.1 4.3 0.11 12.6 4.3 1.7 1 1 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 AJA92082.1 - 0.12 12.5 1.0 0.15 12.1 1.0 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Iso_dh PF00180.20 AJA92083.1 - 1e-80 271.5 0.1 1.3e-80 271.2 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase OTCace_N PF02729.21 AJA92084.1 - 1.9e-42 144.8 0.0 3.5e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AJA92084.1 - 5.4e-30 104.5 0.0 8.6e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF2149 PF09919.9 AJA92084.1 - 0.016 15.4 0.4 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) SNARE_assoc PF09335.11 AJA92085.1 - 1.2e-21 77.5 6.7 1.2e-21 77.4 5.3 1.7 1 1 1 2 2 2 1 SNARE associated Golgi protein GDP_Man_Dehyd PF16363.5 AJA92086.1 - 5.8e-76 256.0 0.2 6.7e-76 255.8 0.2 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AJA92086.1 - 2.9e-55 187.4 0.0 3.8e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AJA92086.1 - 6e-19 68.1 0.5 7.9e-19 67.7 0.5 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AJA92086.1 - 7.2e-14 51.6 0.0 1.2e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AJA92086.1 - 4.5e-12 45.7 0.4 5.1e-11 42.2 0.4 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 AJA92086.1 - 6.6e-12 45.2 0.1 3.5e-11 42.8 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AJA92086.1 - 1.7e-05 24.8 0.0 0.00016 21.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 AJA92086.1 - 0.0012 19.2 0.4 0.0036 17.6 0.0 2.0 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 AJA92086.1 - 0.039 13.4 0.3 0.14 11.6 0.3 1.8 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 AJA92086.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 KR domain GrpE PF01025.19 AJA92087.1 - 4.5e-36 124.0 3.9 5.4e-36 123.8 3.9 1.0 1 0 0 1 1 1 1 GrpE Prominin PF05478.11 AJA92087.1 - 0.026 12.5 1.0 0.029 12.4 1.0 1.1 1 0 0 1 1 1 0 Prominin M PF02370.16 AJA92087.1 - 0.28 11.9 2.6 2.8 8.8 1.0 2.9 2 0 0 2 2 2 0 M protein repeat UPF0242 PF06785.11 AJA92087.1 - 0.34 11.0 4.6 0.41 10.7 4.2 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ATP-grasp_5 PF13549.6 AJA92089.1 - 1.2e-65 221.0 0.3 1.9e-65 220.4 0.3 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 AJA92089.1 - 1.7e-48 163.9 0.2 4.6e-48 162.5 0.2 1.8 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AJA92089.1 - 1.5e-25 90.0 0.2 6.7e-25 87.8 0.1 2.2 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.19 AJA92089.1 - 3.6e-09 37.2 0.2 1.5e-08 35.2 0.2 2.2 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 AJA92089.1 - 4e-07 29.8 2.6 4.5e-07 29.6 0.8 2.0 2 0 0 2 2 2 1 ATP-grasp domain TPP_enzyme_M PF00205.22 AJA92089.1 - 0.0014 18.4 1.1 0.93 9.2 0.0 3.8 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, central domain ATP-grasp PF02222.22 AJA92089.1 - 0.031 13.8 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Peripla_BP_4 PF13407.6 AJA92089.1 - 0.035 13.7 1.7 1.1 8.8 0.1 3.2 4 0 0 4 4 4 0 Periplasmic binding protein domain Hydantoinase_A PF01968.18 AJA92089.1 - 0.054 12.8 0.5 0.19 11.0 0.0 1.9 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase Sacchrp_dh_NADP PF03435.18 AJA92089.1 - 0.15 12.3 0.1 0.46 10.8 0.1 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADIP PF11559.8 AJA92091.1 - 0.0053 16.8 0.2 0.0059 16.7 0.2 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DivIC PF04977.15 AJA92091.1 - 0.021 14.6 0.8 0.038 13.8 0.8 1.5 1 1 0 1 1 1 0 Septum formation initiator CorA PF01544.18 AJA92091.1 - 0.033 13.5 0.1 0.033 13.5 0.1 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CCDC-167 PF15188.6 AJA92091.1 - 0.047 14.0 0.3 0.054 13.8 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 ABC_tran_CTD PF16326.5 AJA92091.1 - 0.074 13.3 0.1 0.087 13.1 0.1 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF1192 PF06698.11 AJA92091.1 - 0.08 13.0 2.4 0.17 11.9 2.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3375 PF11855.8 AJA92091.1 - 0.11 11.4 0.2 0.12 11.2 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Ribosomal_S27 PF01599.19 AJA92092.1 - 1.6e-20 73.0 5.9 1.8e-20 72.8 5.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27a Cytochrome_C7 PF14522.6 AJA92092.1 - 0.0044 17.0 1.7 0.0049 16.8 1.7 1.1 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c Nudix_N_2 PF14803.6 AJA92092.1 - 0.0044 16.9 1.9 1.7 8.6 0.1 2.2 2 0 0 2 2 2 2 Nudix N-terminal Ephrin_rec_like PF07699.13 AJA92092.1 - 0.0055 16.4 0.5 0.0083 15.9 0.5 1.2 1 0 0 1 1 1 1 Putative ephrin-receptor like DUF1451 PF07295.11 AJA92092.1 - 0.013 15.5 0.8 0.014 15.4 0.8 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain Ribosomal_L37e PF01907.19 AJA92092.1 - 0.015 15.5 2.9 0.025 14.7 2.9 1.4 1 0 0 1 1 1 0 Ribosomal protein L37e IBR PF01485.21 AJA92092.1 - 0.024 14.9 1.6 0.028 14.6 1.6 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain NCD3G PF07562.14 AJA92092.1 - 0.028 14.4 1.0 0.037 14.0 1.0 1.3 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR DZR PF12773.7 AJA92092.1 - 0.092 12.8 2.9 0.21 11.6 2.9 1.6 1 1 0 1 1 1 0 Double zinc ribbon PknG_rubred PF16919.5 AJA92092.1 - 1.5 9.0 7.1 4.3 7.5 7.0 1.7 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain YhfH PF14149.6 AJA92092.1 - 4.1 7.5 8.5 96 3.1 7.9 2.2 1 1 1 2 2 2 0 YhfH-like protein zf-C2H2_4 PF13894.6 AJA92093.1 - 0.0028 18.4 0.2 0.0036 18.0 0.2 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 AJA92093.1 - 0.0037 17.6 0.1 0.0041 17.4 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 AJA92093.1 - 0.037 14.3 0.1 0.047 14.0 0.1 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.12 AJA92093.1 - 0.042 12.4 0.0 0.042 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Actin_micro PF17003.5 AJA92093.1 - 0.073 12.2 0.1 0.073 12.2 0.1 1.0 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2 PF00096.26 AJA92093.1 - 0.082 13.4 0.2 0.12 12.9 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type PfkB PF00294.24 AJA92094.1 - 1.2e-09 37.9 0.0 1.8e-09 37.3 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase WD40_3 PF15911.5 AJA92094.1 - 0.1 12.6 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat Phos_pyr_kin PF08543.12 AJA92094.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase NIR_SIR PF01077.22 AJA92095.1 - 3.9e-41 140.2 0.0 3.4e-30 104.7 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AJA92095.1 - 9.6e-32 108.7 0.0 3.8e-16 58.7 0.0 2.8 2 1 1 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain CobD_Cbib PF03186.13 AJA92096.1 - 8.1e-87 290.9 0.0 1e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 CobD/Cbib protein DUF4199 PF13858.6 AJA92096.1 - 0.34 11.3 6.9 0.21 12.0 1.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) Cys_rich_CWC PF14375.6 AJA92097.1 - 0.026 14.9 12.1 0.11 13.0 12.1 1.9 1 1 0 1 1 1 0 Cysteine-rich CWC DM PF00751.18 AJA92097.1 - 0.027 14.4 0.6 0.027 14.4 0.6 2.3 2 0 0 2 2 2 0 DM DNA binding domain Flavi_propep PF01570.17 AJA92097.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.1 1 1 1 2 2 2 0 Flavivirus polyprotein propeptide Zn-ribbon_8 PF09723.10 AJA92097.1 - 6 7.1 9.4 1.5e+02 2.6 9.4 2.1 1 1 0 1 1 1 0 Zinc ribbon domain FeoB_N PF02421.18 AJA92099.1 - 5.3e-15 55.3 0.1 8.5e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 AJA92099.1 - 1.3e-13 51.0 0.3 2.3e-13 50.2 0.3 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gate PF07670.14 AJA92099.1 - 6.6e-07 29.6 19.9 1.2e-05 25.6 1.8 3.1 3 0 0 3 3 3 2 Nucleoside recognition AIG1 PF04548.16 AJA92099.1 - 1.2e-06 28.0 0.5 2.3e-06 27.1 0.5 1.4 1 1 0 1 1 1 1 AIG1 family PduV-EutP PF10662.9 AJA92099.1 - 0.0014 18.4 0.1 0.0023 17.7 0.1 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 AJA92099.1 - 0.0022 18.1 2.9 0.014 15.5 0.1 2.3 1 1 1 2 2 2 1 Dynamin family Roc PF08477.13 AJA92099.1 - 0.012 15.8 0.5 0.036 14.3 0.2 2.1 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AJA92099.1 - 0.035 13.5 0.1 0.068 12.6 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 AJA92099.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AJA92099.1 - 0.047 13.6 1.4 0.15 12.0 0.1 2.3 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 AJA92099.1 - 0.057 13.9 0.0 0.099 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Saf_2TM PF18303.1 AJA92099.1 - 0.06 12.9 1.1 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Ras PF00071.22 AJA92099.1 - 0.061 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Ras family AAA_24 PF13479.6 AJA92099.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain Cob_adeno_trans PF01923.18 AJA92100.1 - 3.9e-53 180.0 0.0 4.3e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase TFIIB PF00382.19 AJA92101.1 - 1.4e-19 69.9 1.8 8.4e-09 35.4 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJA92101.1 - 4.6e-05 22.9 5.0 4.6e-05 22.9 5.0 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_C PF02984.19 AJA92101.1 - 0.084 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Cyclin, C-terminal domain Zn_Tnp_IS91 PF14319.6 AJA92101.1 - 1.2 9.2 5.0 19 5.3 0.1 2.8 3 0 0 3 3 3 0 Transposase zinc-binding domain DZR PF12773.7 AJA92101.1 - 1.5 8.9 8.8 0.55 10.3 0.6 2.9 2 1 0 2 2 2 0 Double zinc ribbon Ribul_P_3_epim PF00834.19 AJA92102.1 - 8.7e-53 178.7 0.2 1.3e-52 178.1 0.2 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Transketolase_N PF00456.21 AJA92102.1 - 2.7e-44 151.5 0.5 5.3e-43 147.3 0.5 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 AJA92102.1 - 2.7e-06 26.8 0.0 0.00054 19.3 0.0 2.4 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 AJA92102.1 - 4.1e-05 22.7 0.0 7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 AJA92102.1 - 9.6e-05 22.2 0.0 0.00023 21.0 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 AJA92102.1 - 0.00013 21.0 0.7 0.00059 18.7 0.7 2.1 1 1 0 1 1 1 1 XFP N-terminal domain Acetyltransf_1 PF00583.25 AJA92103.1 - 1.4e-16 60.8 0.0 1.8e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AJA92103.1 - 3.3e-09 37.0 0.3 6.5e-09 36.1 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AJA92103.1 - 3.6e-09 36.6 0.3 5.9e-09 35.9 0.3 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AJA92103.1 - 1.9e-08 34.2 0.1 1.4e-07 31.4 0.0 2.0 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 AJA92103.1 - 0.01 15.5 0.0 0.061 13.0 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AJA92103.1 - 0.026 15.2 0.0 0.034 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AJA92103.1 - 0.031 14.4 0.0 0.06 13.4 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AJA92103.1 - 0.039 14.1 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 AJA92103.1 - 0.058 13.5 0.5 0.083 13.0 0.5 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1743 PF08489.11 AJA92104.1 - 1.4e-36 125.0 0.0 5.5e-36 123.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1743) C1_1 PF00130.22 AJA92104.1 - 0.0067 16.3 4.5 0.013 15.4 4.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) MCM_OB PF17207.3 AJA92104.1 - 0.12 12.2 2.0 0.52 10.2 2.0 2.0 1 1 0 1 1 1 0 MCM OB domain RNA_POL_M_15KD PF02150.16 AJA92104.1 - 0.62 10.0 3.2 1.3 9.0 3.2 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit PolC_DP2 PF03833.13 AJA92105.1 - 0 1023.8 0.0 0 1023.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.12 AJA92105.1 - 2 8.5 14.7 6.2 6.9 0.1 2.8 2 1 0 2 2 2 0 zinc-ribbons TusA PF01206.17 AJA92106.1 - 3.7e-21 74.7 0.0 4.1e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 AJA92106.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Ribosomal_L24e PF01246.20 AJA92107.1 - 6.1e-20 71.2 3.6 6.4e-20 71.2 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FLZ PF04570.14 AJA92107.1 - 0.0053 16.2 0.3 0.01 15.3 0.3 1.4 1 1 0 1 1 1 1 zinc-finger of the FCS-type, C2-C2 zf-FCS PF06467.14 AJA92107.1 - 0.0066 16.4 1.2 0.012 15.5 1.2 1.5 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif NosL PF05573.12 AJA92107.1 - 0.03 14.7 0.0 0.034 14.5 0.0 1.1 1 0 0 1 1 1 0 NosL DUF2256 PF10013.9 AJA92107.1 - 0.07 13.3 5.3 5.2 7.3 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Ribosomal_L31e PF01198.19 AJA92108.1 - 2.2e-16 59.9 0.4 5.1e-16 58.7 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L31e CTP_transf_like PF01467.26 AJA92109.1 - 5e-15 55.9 0.0 5.8e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 AJA92109.1 - 0.032 14.1 0.5 0.085 12.7 0.2 1.9 2 1 0 2 2 2 0 FAD synthetase DpaA_N PF16924.5 AJA92109.1 - 0.13 12.3 0.1 4.4 7.4 0.0 2.1 1 1 1 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain UvrB_inter PF17757.1 AJA92110.1 - 2.2e-29 101.5 3.5 2.3e-29 101.4 1.0 2.5 3 0 0 3 3 3 1 UvrB interaction domain UvrB PF12344.8 AJA92110.1 - 4.1e-21 74.5 4.9 1e-20 73.3 4.9 1.7 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 AJA92110.1 - 8.8e-19 67.9 0.8 4.3e-18 65.7 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AJA92110.1 - 1.2e-07 31.9 0.1 1.2e-07 31.9 0.1 3.0 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AJA92110.1 - 2.9e-07 30.4 0.4 9.6e-05 22.2 0.1 3.4 3 1 0 3 3 3 1 DEAD/DEAH box helicase UVR PF02151.19 AJA92110.1 - 2.9e-06 26.8 1.3 2.9e-06 26.8 1.3 2.7 2 0 0 2 2 2 1 UvrB/uvrC motif Microtub_bd PF16796.5 AJA92110.1 - 0.022 14.7 0.7 0.073 13.0 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding AAA PF00004.29 AJA92110.1 - 0.046 14.2 0.9 1.9 8.9 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AJA92110.1 - 0.058 13.1 0.0 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rhomboid_N PF12122.8 AJA92110.1 - 0.061 13.5 0.0 7.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease AAA_33 PF13671.6 AJA92110.1 - 0.093 12.9 0.0 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AJA92110.1 - 0.13 12.6 0.4 18 5.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF393 PF04134.12 AJA92111.1 - 0.11 13.8 0.0 0.16 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF393 Topo-VIb_trans PF09239.11 AJA92112.1 - 2.7e-57 193.0 0.0 4.4e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c PF02518.26 AJA92112.1 - 8e-10 39.2 0.0 1.7e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AJA92112.1 - 3.1e-05 23.8 0.0 7.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FbpA PF05833.11 AJA92112.1 - 0.0029 16.4 0.0 0.0071 15.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 AJA92112.1 - 0.0053 17.1 0.1 2 8.8 0.0 2.5 2 0 0 2 2 2 1 Ribosomal protein S13/S18 Lyase_1 PF00206.20 AJA92113.1 - 1.1e-84 284.5 0.3 1.4e-84 284.2 0.3 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AJA92113.1 - 4.3e-13 49.4 0.0 1.4e-12 47.8 0.0 2.0 1 0 0 1 1 1 1 Fumarase C C-terminus ToxN_toxin PF13958.6 AJA92113.1 - 0.12 12.6 1.9 0.12 12.6 0.2 1.9 2 0 0 2 2 2 0 Toxin ToxN, type III toxin-antitoxin system Chordopox_A30L PF06015.12 AJA92113.1 - 0.14 12.0 2.4 0.18 11.7 0.2 2.3 2 0 0 2 2 2 0 Chordopoxvirus A30L protein DUF3929 PF13066.6 AJA92113.1 - 0.14 12.2 0.2 0.51 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) PAPS_reduct PF01507.19 AJA92114.1 - 1.2e-39 136.1 0.0 1.5e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RNA_pol_N PF01194.17 AJA92115.1 - 2e-06 28.0 1.4 2e-06 28.0 1.4 1.4 2 0 0 2 2 2 1 RNA polymerases N / 8 kDa subunit Carbam_trans_N PF02543.15 AJA92116.1 - 2.7e-89 300.2 0.2 3.4e-89 299.8 0.2 1.1 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus Carbam_trans_C PF16861.5 AJA92116.1 - 2.4e-74 248.5 0.0 7.1e-74 247.0 0.0 1.7 2 0 0 2 2 2 1 Carbamoyltransferase C-terminus Peptidase_M22 PF00814.25 AJA92116.1 - 0.00053 19.8 0.0 0.046 13.4 0.0 2.3 2 0 0 2 2 2 2 Glycoprotease family Sua5_yciO_yrdC PF01300.18 AJA92116.1 - 0.0033 17.0 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination PepSY PF03413.19 AJA92118.1 - 0.0062 17.1 1.1 0.4 11.3 1.1 2.3 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain His_Phos_1 PF00300.22 AJA92119.1 - 1.6e-48 165.0 0.0 1.8e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Replicase PF03090.17 AJA92120.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Replicase family DUF4035 PF13227.6 AJA92120.1 - 0.17 11.7 0.1 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4035) Oxidored_q3 PF00499.20 AJA92121.1 - 2.6e-23 82.4 11.5 3.7e-23 81.9 11.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 YrhC PF14143.6 AJA92121.1 - 0.37 10.9 0.1 0.37 10.9 0.1 3.2 3 1 1 4 4 4 0 YrhC-like protein AAA_3 PF07726.11 AJA92122.1 - 2.7e-64 214.9 0.0 5.2e-64 214.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AJA92122.1 - 7.2e-21 73.8 0.1 1.4e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 AJA92122.1 - 1.7e-15 57.2 0.0 3.2e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AJA92122.1 - 6.6e-08 31.9 0.0 1.7e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 MCM P-loop domain RuvB_N PF05496.12 AJA92122.1 - 5.4e-06 26.2 0.3 8.7e-05 22.3 0.1 2.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 AJA92122.1 - 0.00016 21.5 0.1 0.0011 18.7 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 AJA92122.1 - 0.00031 20.2 0.3 0.018 14.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 AJA92122.1 - 0.00047 20.6 0.3 0.0024 18.3 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 AJA92122.1 - 0.055 13.8 1.9 8.6 6.7 0.3 3.2 2 1 1 3 3 3 0 AAA domain HTH_20 PF12840.7 AJA92123.1 - 0.00023 21.2 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AJA92123.1 - 0.00064 19.5 0.4 0.0019 18.1 0.1 1.9 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 AJA92123.1 - 0.0032 17.3 0.2 0.0038 17.1 0.2 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit DUF742 PF05331.11 AJA92123.1 - 0.0087 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF742) DUF3839 PF12943.7 AJA92123.1 - 0.021 14.3 0.3 0.027 13.9 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3839) DUF2806 PF10987.8 AJA92123.1 - 0.037 13.9 0.1 0.042 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) SdiA-regulated PF06977.11 AJA92123.1 - 0.098 11.9 0.0 0.1 11.8 0.0 1.0 1 0 0 1 1 1 0 SdiA-regulated Ribosomal_S19 PF00203.21 AJA92124.1 - 8.7e-28 96.0 0.2 1.2e-27 95.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Peptidase_M56 PF05569.11 AJA92124.1 - 0.18 11.0 0.1 0.22 10.7 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DALR_1 PF05746.15 AJA92125.1 - 7.8e-31 106.7 0.5 4.5e-29 101.0 0.0 2.4 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 AJA92125.1 - 3.9e-26 91.8 7.4 8.1e-20 71.1 2.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 AJA92125.1 - 7.8e-15 55.2 0.1 2.3e-14 53.7 0.1 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1f PF01921.18 AJA92125.1 - 0.0063 15.5 0.2 0.024 13.5 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 AJA92125.1 - 0.0079 15.6 0.8 0.022 14.1 0.2 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 AJA92125.1 - 0.031 13.0 2.6 0.15 10.8 0.1 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (M) DUF3800 PF12686.7 AJA92125.1 - 6 7.5 7.5 4.3 8.0 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) PMSR PF01625.21 AJA92126.1 - 5.5e-64 215.0 4.4 6.1e-64 214.8 4.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Vsr PF03852.15 AJA92126.1 - 0.097 12.5 0.1 1.5 8.8 0.3 2.2 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr HMA PF00403.26 AJA92126.1 - 0.12 12.8 0.1 1.5 9.4 0.0 2.5 3 0 0 3 3 3 0 Heavy-metal-associated domain Glycos_transf_2 PF00535.26 AJA92127.1 - 2.8e-29 102.1 0.0 3.8e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AJA92127.1 - 1.7e-17 64.1 0.0 2.4e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AJA92127.1 - 1.5e-12 47.3 0.0 2.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 AJA92127.1 - 6.3e-12 45.6 0.1 8.2e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AJA92127.1 - 0.00052 20.5 0.0 0.00092 19.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AJA92127.1 - 0.095 12.6 0.0 0.31 10.9 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family group 2 VasI PF11319.8 AJA92127.1 - 0.096 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 VIT1 PF01988.19 AJA92127.1 - 0.55 10.1 4.0 0.11 12.3 0.4 1.8 2 0 0 2 2 2 0 VIT family Sarcolipin PF05366.11 AJA92127.1 - 2.7 7.8 5.9 0.78 9.5 1.4 2.3 2 0 0 2 2 2 0 Sarcolipin HIT PF01230.23 AJA92128.1 - 3.3e-24 85.5 1.0 4e-24 85.2 1.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AJA92128.1 - 9.7e-15 55.1 0.8 1.3e-14 54.6 0.8 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 AJA92128.1 - 0.0025 17.7 0.2 0.0031 17.4 0.2 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 COX14 PF14880.6 AJA92129.1 - 0.0023 17.7 0.2 0.0031 17.3 0.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DHHA1 PF02272.19 AJA92130.1 - 4.2e-16 59.6 0.5 4.2e-16 59.6 0.5 2.0 3 0 0 3 3 3 1 DHHA1 domain DHH PF01368.20 AJA92130.1 - 0.00061 20.0 1.0 0.0012 19.0 1.0 1.5 1 0 0 1 1 1 1 DHH family Ribosomal_L7Ae PF01248.26 AJA92131.1 - 1.1e-25 89.1 0.1 1.4e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PAD PF03068.15 AJA92131.1 - 0.041 12.9 0.0 0.048 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Prok-JAB PF14464.6 AJA92133.1 - 5.1e-21 74.6 0.0 6.1e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RadC PF04002.15 AJA92133.1 - 0.00054 19.9 0.1 0.0009 19.2 0.1 1.4 1 1 0 1 1 1 1 RadC-like JAB domain JAB PF01398.21 AJA92133.1 - 0.00076 19.5 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Toxin-JAB1 PF15659.6 AJA92133.1 - 0.0081 16.5 0.2 0.015 15.6 0.2 1.4 1 0 0 1 1 1 1 JAB-like toxin 1 tRNA_bind_3 PF17176.4 AJA92133.1 - 0.048 14.0 0.0 0.067 13.5 0.0 1.3 1 0 0 1 1 1 0 tRNA-binding domain PhoU_div PF01865.16 AJA92134.1 - 2e-22 79.6 7.5 2.3e-22 79.4 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF47 AIP3 PF03915.13 AJA92134.1 - 0.0077 15.4 0.2 0.014 14.5 0.2 1.5 1 1 0 1 1 1 1 Actin interacting protein 3 DUF5406 PF17400.2 AJA92134.1 - 0.052 14.0 0.9 4.5 7.7 0.2 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5406) PUA PF01472.20 AJA92135.1 - 1e-17 63.9 0.0 1.7e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 AJA92135.1 - 0.0077 16.5 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain SH3_1 PF00018.28 AJA92135.1 - 5.1 6.8 7.6 32 4.3 0.6 3.3 3 0 0 3 3 3 0 SH3 domain CbiG_N PF11760.8 AJA92136.1 - 8.5e-33 112.2 0.2 1.5e-32 111.5 0.2 1.4 1 0 0 1 1 1 1 Cobalamin synthesis G N-terminal CbiG_C PF01890.16 AJA92136.1 - 1.3e-26 93.4 0.1 4.1e-26 91.8 0.0 1.8 2 0 0 2 2 2 1 Cobalamin synthesis G C-terminus CbiG_mid PF11761.8 AJA92136.1 - 4.6e-12 45.9 0.0 1.4e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Cobalamin biosynthesis central region SpoU_sub_bind PF08032.12 AJA92136.1 - 0.049 13.9 0.0 0.24 11.7 0.0 2.2 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding FAD_binding_2 PF00890.24 AJA92138.1 - 2.7e-05 23.4 0.0 0.0058 15.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 AJA92138.1 - 0.0034 16.7 0.9 1.9 7.7 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 AJA92138.1 - 0.0035 16.6 0.3 2.3 7.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AJA92138.1 - 0.0091 15.6 1.7 0.19 11.3 0.0 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.18 AJA92138.1 - 0.013 14.1 0.0 0.13 10.7 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor Trp_halogenase PF04820.14 AJA92138.1 - 0.023 13.6 0.0 0.26 10.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 AJA92138.1 - 2.4 7.4 5.0 24 4.1 5.0 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase Ephrin_rec_like PF07699.13 AJA92139.1 - 0.0025 17.6 4.7 0.0025 17.6 4.7 1.4 1 1 0 1 1 1 1 Putative ephrin-receptor like Polo_box_3 PF18544.1 AJA92140.1 - 0.046 14.4 0.7 0.053 14.2 0.7 1.1 1 0 0 1 1 1 0 Polo box domain AIRC PF00731.20 AJA92141.1 - 1.6e-57 193.3 0.2 2.2e-57 192.8 0.2 1.2 1 0 0 1 1 1 1 AIR carboxylase PrpR_N PF06506.11 AJA92141.1 - 0.0037 16.9 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 Propionate catabolism activator Asp_Glu_race PF01177.22 AJA92141.1 - 0.017 15.0 0.1 0.024 14.5 0.1 1.5 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase DUF521 PF04412.13 AJA92142.1 - 1.2e-112 376.6 0.0 1.4e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF2963 PF11178.8 AJA92142.1 - 0.0027 17.4 1.7 2.3 8.0 0.2 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF2963) TPR_1 PF00515.28 AJA92143.1 - 2.4e-11 42.9 0.2 0.0016 18.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AJA92143.1 - 1.7e-10 40.2 0.0 0.015 15.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 AJA92143.1 - 2.5e-08 34.3 0.3 5.5e-06 26.8 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 AJA92143.1 - 3.4e-08 33.1 0.5 0.087 13.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJA92143.1 - 6.6e-08 32.5 0.0 0.18 11.9 0.0 3.3 2 1 1 3 3 3 3 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 AJA92143.1 - 3.9e-07 30.3 0.1 0.00076 19.7 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AJA92143.1 - 4.8e-07 30.1 0.0 0.022 15.5 0.0 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 AJA92143.1 - 3e-06 27.2 0.3 0.18 12.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 AJA92143.1 - 4.3e-06 26.8 0.0 0.0099 16.0 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 AJA92143.1 - 0.00017 22.2 0.0 0.0072 17.0 0.0 2.2 1 1 0 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AJA92143.1 - 0.0027 18.2 0.1 1.4 9.4 0.0 2.4 1 1 1 2 2 2 1 Alkyl sulfatase dimerisation NARP1 PF12569.8 AJA92143.1 - 0.0056 15.7 0.1 0.26 10.2 0.0 2.0 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 Peptidase_C39 PF03412.15 AJA92143.1 - 0.017 14.9 0.2 0.11 12.3 0.0 2.1 1 1 1 2 2 2 0 Peptidase C39 family ANAPC3 PF12895.7 AJA92143.1 - 0.027 14.7 0.3 0.079 13.2 0.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4919 PF16266.5 AJA92143.1 - 0.097 12.6 0.1 0.097 12.6 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4919) TPR_20 PF14561.6 AJA92143.1 - 0.11 12.9 0.3 7.5 7.0 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1815 PF08844.10 AJA92144.1 - 0.042 13.8 0.1 0.049 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Lum_binding PF00677.17 AJA92144.1 - 0.051 13.6 0.0 0.051 13.6 0.0 1.1 1 0 0 1 1 1 0 Lumazine binding domain Bac_luciferase PF00296.20 AJA92145.1 - 5.9e-54 183.6 0.0 8.1e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SGL PF08450.12 AJA92146.1 - 0.00025 20.7 3.6 1.8 8.1 0.0 4.6 3 2 0 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 AJA92146.1 - 0.0087 16.1 0.1 0.72 10.0 0.0 3.1 2 0 0 2 2 2 1 NHL repeat Reg_prop PF07494.11 AJA92146.1 - 0.074 13.3 6.2 18 6.0 0.1 4.6 4 0 0 4 4 4 0 Two component regulator propeller FliD_N PF02465.18 AJA92146.1 - 0.076 13.7 1.1 0.17 12.6 1.1 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus KID PF02524.14 AJA92147.1 - 0.075 13.2 2.1 13 6.4 0.1 2.7 2 0 0 2 2 2 0 KID repeat tRNA-synt_2b PF00587.25 AJA92148.1 - 8.8e-39 133.3 0.9 8.8e-39 133.3 0.9 1.7 2 1 1 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AJA92148.1 - 1.4e-23 83.2 8.0 1.4e-23 83.2 8.0 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain FlgN PF05130.12 AJA92148.1 - 0.09 13.3 2.3 0.19 12.2 2.3 1.5 1 0 0 1 1 1 0 FlgN protein I_LWEQ PF01608.17 AJA92148.1 - 0.54 10.5 4.1 5 7.3 0.0 2.8 2 1 0 3 3 3 0 I/LWEQ domain BLOC1_2 PF10046.9 AJA92148.1 - 1 9.7 6.5 0.42 10.9 3.4 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_15 PF13175.6 AJA92149.1 - 3.5e-25 89.5 4.7 3.5e-25 89.5 4.7 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 AJA92149.1 - 3.2e-15 56.7 10.5 9.9e-15 55.1 6.5 3.0 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AJA92149.1 - 0.0023 18.2 0.4 0.41 10.9 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AJA92149.1 - 0.004 17.7 8.4 0.004 17.7 8.4 3.4 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 AJA92149.1 - 0.011 16.3 0.1 0.011 16.3 0.1 2.8 3 1 0 3 3 3 0 ABC transporter AAA_27 PF13514.6 AJA92149.1 - 0.013 15.1 0.1 0.098 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AJA92149.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 AJA92149.1 - 0.038 13.4 0.0 6 6.2 0.0 2.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF3980 PF13140.6 AJA92150.1 - 0.14 12.6 0.2 0.73 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) WDCP PF15390.6 AJA92152.1 - 0.48 8.8 13.6 0.53 8.6 13.6 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Etmic-2 PF06670.11 AJA92152.1 - 1.1 8.1 6.9 1.6 7.6 6.9 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 FUSC PF04632.12 AJA92152.1 - 2.7 6.4 5.5 3 6.3 5.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Allexi_40kDa PF05549.11 AJA92152.1 - 2.7 7.4 6.0 3.4 7.1 6.0 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF3482 PF11981.8 AJA92152.1 - 4.9 6.5 14.7 0.52 9.7 2.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3482) Methyltransf_23 PF13489.6 AJA92153.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Creatininase PF02633.14 AJA92154.1 - 2.1e-52 178.0 0.0 2.7e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase DUF4473 PF14747.6 AJA92154.1 - 0.016 15.7 0.1 0.036 14.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) GATase_5 PF13507.6 AJA92155.1 - 1.2e-41 142.5 0.0 2.7e-41 141.4 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 AJA92155.1 - 1.2e-08 34.8 0.0 3.7e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 AJA92155.1 - 3.3e-08 33.5 0.0 7.5e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 AJA92155.1 - 4.8e-07 29.7 0.0 7.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 AJA92155.1 - 0.0071 16.1 0.0 0.017 14.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase C26 CDT1 PF08839.11 AJA92157.1 - 0.025 14.9 2.4 0.062 13.6 2.4 1.7 1 0 0 1 1 1 0 DNA replication factor CDT1 like MRP-S23 PF10484.9 AJA92157.1 - 5 7.4 8.6 0.45 10.8 1.8 2.6 2 1 2 4 4 4 0 Mitochondrial ribosomal protein S23 CBFD_NFYB_HMF PF00808.23 AJA92158.1 - 2.3e-11 43.8 0.2 2.7e-11 43.6 0.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 AJA92158.1 - 5.6e-05 23.5 0.0 5.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 AJA92158.1 - 9.2e-05 22.5 0.1 0.0001 22.4 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 AJA92158.1 - 0.00011 22.6 0.1 0.00018 21.8 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 AJA92158.1 - 0.0043 17.1 0.0 0.005 16.9 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 AJA92158.1 - 0.015 15.3 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Bromodomain associated TAF PF02969.17 AJA92158.1 - 0.031 14.4 0.5 0.04 14.1 0.5 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TFIID-18kDa PF02269.16 AJA92158.1 - 0.032 14.3 0.0 0.033 14.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.13 AJA92158.1 - 0.12 12.9 0.1 0.15 12.6 0.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Helicase_C PF00271.31 AJA92159.1 - 5.8e-12 45.9 0.0 3.3e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 AJA92159.1 - 3.9e-08 33.2 0.0 4.1e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 AJA92159.1 - 0.00022 21.3 4.8 0.02 14.9 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit IcmF-related PF06761.12 AJA92159.1 - 0.11 11.9 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing DZR PF12773.7 AJA92159.1 - 0.22 11.6 5.8 0.86 9.7 1.2 2.6 2 0 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 AJA92159.1 - 0.38 10.9 10.5 3.5 7.8 0.3 3.9 3 1 0 3 3 3 0 Zinc ribbon domain Lar_restr_allev PF14354.6 AJA92159.1 - 0.76 10.2 5.7 8.4 6.9 0.7 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar RNHCP PF12647.7 AJA92159.1 - 1 9.4 3.9 25 4.9 0.4 3.4 3 1 1 4 4 4 0 RNHCP domain OrfB_Zn_ribbon PF07282.11 AJA92159.1 - 2 8.4 10.4 0.28 11.1 0.6 3.2 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.12 AJA92159.1 - 2.3 8.3 9.1 4.3 7.4 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbons zf-LITAF-like PF10601.9 AJA92159.1 - 3.1 8.1 7.7 0.2 12.0 0.4 2.5 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 AJA92159.1 - 3.7 7.6 7.4 6.6 6.8 0.3 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Pyr_redox_3 PF13738.6 AJA92161.1 - 5.6e-94 314.8 0.1 7.9e-94 314.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AJA92161.1 - 1.1e-15 57.7 0.2 3.1e-14 52.9 0.2 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AJA92161.1 - 1.7e-10 40.2 0.1 0.037 12.7 0.0 4.0 5 0 0 5 5 5 3 HI0933-like protein K_oxygenase PF13434.6 AJA92161.1 - 7.4e-10 38.5 0.0 2.5e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 AJA92161.1 - 2.6e-09 37.5 3.7 0.016 15.7 0.4 4.1 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AJA92161.1 - 1.1e-05 25.2 0.0 0.98 8.9 0.0 3.4 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AJA92161.1 - 1.3e-05 25.4 0.5 0.042 14.1 0.1 2.7 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AJA92161.1 - 3.1e-05 23.2 0.2 1.8 7.6 0.0 3.9 3 1 1 4 4 4 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AJA92161.1 - 3.7e-05 23.1 0.1 0.0011 18.3 0.3 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 AJA92161.1 - 4.9e-05 23.4 0.5 1 9.3 0.0 3.4 2 2 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 AJA92161.1 - 0.0021 17.2 0.0 7.5 5.5 0.0 3.3 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 AJA92161.1 - 0.0094 15.2 0.2 0.28 10.4 0.2 2.2 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 AJA92161.1 - 0.078 13.2 0.5 12 6.2 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain FAD_oxidored PF12831.7 AJA92161.1 - 0.094 12.0 0.1 14 4.9 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Chorismate_synt PF01264.21 AJA92162.1 - 9.8e-132 438.6 0.6 1.1e-131 438.4 0.6 1.0 1 0 0 1 1 1 1 Chorismate synthase BCIP PF13862.6 AJA92162.1 - 0.076 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 p21-C-terminal region-binding protein dsDNA_bind PF01984.20 AJA92163.1 - 8.4e-22 77.5 0.6 9e-22 77.5 0.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4503 PF14951.6 AJA92164.1 - 0.00017 20.2 0.5 0.00017 20.2 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) zinc_ribbon_4 PF13717.6 AJA92164.1 - 0.0018 18.2 4.1 0.023 14.6 4.1 2.1 1 1 0 1 1 1 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AJA92164.1 - 0.0024 17.9 1.7 0.033 14.3 0.6 2.1 2 0 0 2 2 2 1 Zinc ribbon domain zinc_ribbon_5 PF13719.6 AJA92164.1 - 0.0051 16.5 4.8 0.014 15.1 4.8 1.7 1 1 0 1 1 1 1 zinc-ribbon domain zf-RRN7 PF11781.8 AJA92164.1 - 0.013 15.1 0.5 0.025 14.2 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn_Tnp_IS1595 PF12760.7 AJA92164.1 - 0.014 15.4 2.5 0.018 15.0 2.5 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DNA_ligase_ZBD PF03119.16 AJA92164.1 - 0.02 14.9 3.0 0.02 14.9 3.0 2.0 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain UBZ_FAAP20 PF15750.5 AJA92164.1 - 0.029 14.3 0.2 0.035 14.0 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger HypA PF01155.19 AJA92164.1 - 0.04 13.9 1.6 0.079 13.0 1.7 1.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 AJA92164.1 - 0.051 13.1 3.0 0.09 12.3 3.0 1.5 1 1 0 1 1 1 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 AJA92164.1 - 0.076 12.9 1.4 0.076 13.0 1.4 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1451 PF07295.11 AJA92164.1 - 0.12 12.4 1.9 0.13 12.3 0.4 1.7 2 0 0 2 2 2 0 Zinc-ribbon containing domain zf-ribbon_3 PF13248.6 AJA92164.1 - 0.14 11.6 7.2 0.78 9.2 0.9 2.8 2 1 1 3 3 3 0 zinc-ribbon domain Tube PF17212.3 AJA92165.1 - 0.066 13.3 0.0 7.3 6.6 0.0 2.1 1 1 1 2 2 2 0 Tail tubular protein GlutR_N PF05201.15 AJA92166.1 - 9.4e-27 93.6 0.0 1.6e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 AJA92166.1 - 8.7e-19 68.0 0.7 1.6e-18 67.1 0.2 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 AJA92166.1 - 0.052 14.0 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF373 PF04123.13 AJA92168.1 - 8.6e-94 314.7 9.5 1e-93 314.5 9.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF373) SPC12 PF06645.13 AJA92168.1 - 0.068 13.3 0.4 0.35 11.0 0.4 2.2 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF4231 PF14015.6 AJA92168.1 - 2.2 8.8 6.3 3.6 8.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Aminotran_4 PF01063.19 AJA92169.1 - 2e-48 165.2 0.0 2.4e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Hemerythrin PF01814.23 AJA92170.1 - 1.8e-08 35.1 0.4 4.7e-08 33.7 0.1 1.7 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain SUIM_assoc PF16619.5 AJA92170.1 - 0.13 12.4 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Hexose_dehydrat PF03559.14 AJA92171.1 - 3.8e-66 222.4 0.0 4.5e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 NDP-hexose 2,3-dehydratase Cnd1 PF12717.7 AJA92171.1 - 0.018 15.1 0.8 0.026 14.6 0.8 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Helicase_C PF00271.31 AJA92172.1 - 2.3e-22 79.4 0.3 2.3e-22 79.4 0.3 2.4 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AJA92172.1 - 3.1e-22 79.4 0.0 6.7e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AJA92172.1 - 9.9e-18 64.5 0.6 6.1e-17 61.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 AJA92172.1 - 0.00017 21.6 0.0 0.00081 19.4 0.0 2.1 2 0 0 2 2 2 1 Flavivirus DEAD domain DUF3638 PF12340.8 AJA92172.1 - 0.0034 16.8 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) Helicase_C_2 PF13307.6 AJA92172.1 - 0.0044 17.2 0.0 0.059 13.5 0.1 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_19 PF13245.6 AJA92172.1 - 0.011 16.1 0.0 0.04 14.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 AJA92172.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 AJA92172.1 - 0.02 14.6 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_30 PF13604.6 AJA92172.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 AJA92172.1 - 0.044 13.6 0.0 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AJA92172.1 - 0.063 12.9 0.6 0.33 10.5 0.6 2.0 1 1 0 1 1 1 0 AAA domain TPR_2 PF07719.17 AJA92173.1 - 2.2e-14 52.3 2.2 4e-06 26.5 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 AJA92173.1 - 2.5e-12 46.1 4.8 3.9e-08 32.8 0.3 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 AJA92173.1 - 5.1e-12 45.3 2.5 0.068 13.6 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 AJA92173.1 - 1.6e-10 41.4 0.0 0.00089 19.7 0.0 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 AJA92173.1 - 1.2e-09 37.6 6.8 0.0022 18.1 0.2 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 AJA92173.1 - 4.1e-09 36.5 0.1 1.5 9.6 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJA92173.1 - 7.5e-08 32.3 0.5 0.04 14.0 0.0 4.1 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 AJA92173.1 - 5.5e-07 30.1 0.0 9.5e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 AJA92173.1 - 8.7e-07 29.3 0.0 0.62 11.0 0.0 4.2 1 1 4 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 AJA92173.1 - 2e-06 27.4 0.8 0.036 13.7 0.2 3.4 3 1 1 4 4 3 2 TPR repeat ANAPC3 PF12895.7 AJA92173.1 - 9.5e-05 22.6 2.0 0.0051 17.0 0.1 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 AJA92173.1 - 0.00028 19.9 0.8 0.076 11.9 0.1 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 DUF4919 PF16266.5 AJA92173.1 - 0.0029 17.6 0.9 0.57 10.1 0.2 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4919) TPR_7 PF13176.6 AJA92173.1 - 0.0036 17.2 0.0 3.7 7.8 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 AJA92173.1 - 0.0044 17.3 0.1 6.7 7.1 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AJA92173.1 - 0.011 16.2 0.0 0.11 12.9 0.0 2.1 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation Coatomer_E PF04733.14 AJA92173.1 - 0.013 15.0 1.0 0.36 10.2 0.0 2.0 1 1 0 2 2 2 0 Coatomer epsilon subunit TPR_10 PF13374.6 AJA92173.1 - 0.04 13.8 0.0 5.6 7.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Virulence_fact PF13769.6 AJA92173.1 - 0.096 12.9 0.0 6.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Virulence factor USP8_dimer PF08969.11 AJA92173.1 - 0.11 12.7 0.4 0.11 12.7 0.4 2.3 2 2 0 2 2 2 0 USP8 dimerisation domain TPR_9 PF13371.6 AJA92173.1 - 0.21 11.8 0.0 0.86 9.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat OMPdecase PF00215.24 AJA92174.1 - 3.8e-23 82.3 0.0 4.5e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TP_methylase PF00590.20 AJA92175.1 - 1.7e-53 181.7 0.0 1.9e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases tRNA_deacylase PF04414.12 AJA92176.1 - 1.2e-62 211.1 0.0 3.6e-62 209.5 0.0 1.6 2 0 0 2 2 2 1 D-aminoacyl-tRNA deacylase SRP54 PF00448.22 AJA92177.1 - 8.8e-70 234.3 1.9 1.2e-69 233.9 1.9 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 AJA92177.1 - 1.3e-10 41.3 3.8 4e-10 39.8 3.8 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 AJA92177.1 - 1.1e-07 31.8 0.1 1.6e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 AJA92177.1 - 3.2e-06 26.8 0.8 5.7e-06 26.0 0.8 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 AJA92177.1 - 5.2e-05 22.6 0.1 9.2e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin B12-binding PF02310.19 AJA92177.1 - 0.0002 21.4 0.7 0.0064 16.5 0.5 2.9 1 1 1 2 2 2 1 B12 binding domain AAA_22 PF13401.6 AJA92177.1 - 0.00022 21.5 0.0 0.00098 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AJA92177.1 - 0.0008 19.6 0.1 0.0018 18.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain KdpD PF02702.17 AJA92177.1 - 0.003 17.1 1.2 0.0034 16.9 0.1 1.5 2 0 0 2 2 2 1 Osmosensitive K+ channel His kinase sensor domain AAA_19 PF13245.6 AJA92177.1 - 0.0036 17.6 0.1 0.0062 16.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AJA92177.1 - 0.0043 17.0 1.0 0.23 11.4 1.0 2.4 1 1 0 1 1 1 1 NTPase TPP_enzyme_M PF00205.22 AJA92177.1 - 0.007 16.1 0.2 0.11 12.2 0.1 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain PIF1 PF05970.14 AJA92177.1 - 0.0073 15.5 0.2 0.011 14.9 0.2 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA PF00004.29 AJA92177.1 - 0.012 16.1 0.2 0.035 14.5 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CLP1_P PF16575.5 AJA92177.1 - 0.013 15.3 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Thymidylate_kin PF02223.17 AJA92177.1 - 0.014 15.0 0.0 0.072 12.8 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.6 AJA92177.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AJA92177.1 - 0.018 15.5 0.2 0.052 14.1 0.1 1.7 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 AJA92177.1 - 0.018 14.3 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 AJA92177.1 - 0.019 15.4 0.1 0.05 14.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AJA92177.1 - 0.023 14.2 0.2 0.08 12.5 0.2 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region TK PF00265.18 AJA92177.1 - 0.03 14.2 0.2 0.068 13.0 0.2 1.5 1 0 0 1 1 1 0 Thymidine kinase MobB PF03205.14 AJA92177.1 - 0.032 14.1 0.5 0.12 12.3 0.2 2.0 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 AJA92177.1 - 0.035 14.5 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 AJA92177.1 - 0.038 14.0 1.6 0.045 13.8 0.2 1.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.6 AJA92177.1 - 0.039 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AJA92177.1 - 0.041 13.1 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 AJA92177.1 - 0.046 13.4 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AJA92177.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase SPOUT_MTase PF02590.17 AJA92177.1 - 0.071 13.1 0.2 0.46 10.4 0.0 2.2 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase ResIII PF04851.15 AJA92177.1 - 0.11 12.5 0.9 0.28 11.1 0.9 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Trypan_PARP PF05887.11 AJA92177.1 - 0.12 12.4 104.1 0.15 12.0 56.6 2.5 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) MMR_HSR1 PF01926.23 AJA92177.1 - 0.42 10.7 3.2 0.38 10.9 0.8 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase FlgD_ig PF13860.6 AJA92178.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain Methyltransf_11 PF08241.12 AJA92179.1 - 1.6e-08 35.1 0.0 2.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AJA92179.1 - 2.9e-05 23.5 0.0 5.7e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 AJA92179.1 - 0.0011 18.8 0.0 0.0031 17.4 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.6 AJA92179.1 - 0.0017 19.0 0.0 0.0029 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJA92179.1 - 0.0078 16.1 0.0 0.023 14.6 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJA92179.1 - 0.053 14.3 0.0 0.096 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF192 PF02643.15 AJA92180.1 - 1e-28 99.3 0.0 1.4e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 Ph1570 PF09638.10 AJA92180.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Ph1570 protein Snf7 PF03357.21 AJA92181.1 - 0.029 14.0 12.4 0.056 13.0 12.4 1.5 1 1 0 1 1 1 0 Snf7 Exonuc_VII_L PF02601.15 AJA92181.1 - 0.032 13.8 0.9 0.043 13.4 0.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2026 PF09641.10 AJA92181.1 - 0.096 12.3 0.8 0.16 11.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) LSM PF01423.22 AJA92183.1 - 2.3e-17 62.4 2.1 2.6e-17 62.2 2.1 1.0 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.8 AJA92183.1 - 0.013 15.3 0.1 0.035 14.0 0.1 1.6 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Hfq PF17209.3 AJA92183.1 - 0.025 14.2 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Tim44 PF04280.15 AJA92183.1 - 0.071 13.2 0.1 0.072 13.2 0.1 1.0 1 0 0 1 1 1 0 Tim44-like domain HisG PF01634.18 AJA92184.1 - 2.7e-42 144.5 0.0 3.6e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 AJA92184.1 - 6.3e-16 58.3 0.0 1.6e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain PTCB-BRCT PF12738.7 AJA92184.1 - 0.066 13.2 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 twin BRCT domain F420_ligase PF01996.16 AJA92186.1 - 3.1e-44 151.2 0.1 4.6e-44 150.6 0.1 1.2 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase Ribosomal_L14 PF00238.19 AJA92187.1 - 4.7e-33 113.9 1.0 5.4e-33 113.7 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L32e PF01655.18 AJA92188.1 - 7.6e-33 113.2 0.1 9e-33 112.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 AA_permease_C PF13906.6 AJA92189.1 - 0.2 11.7 0.3 0.2 11.7 0.3 2.9 3 0 0 3 3 3 0 C-terminus of AA_permease NCE101 PF11654.8 AJA92189.1 - 1.1 9.0 3.1 0.59 9.9 0.2 2.0 2 0 0 2 2 2 0 Non-classical export protein 1 DUF2878 PF11086.8 AJA92189.1 - 2.2 8.5 8.8 0.35 11.1 1.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2878) Aminotran_1_2 PF00155.21 AJA92190.1 - 2.7e-57 194.6 0.0 3.3e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AJA92190.1 - 0.035 12.6 0.1 0.055 12.0 0.1 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme FbpA PF05833.11 AJA92191.1 - 3.2e-50 171.2 2.3 4.2e-50 170.8 2.3 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 AJA92191.1 - 1.4e-21 77.2 0.1 1.1e-20 74.3 0.0 2.3 2 0 0 2 2 2 1 NFACT protein RNA binding domain H2TH PF06831.14 AJA92191.1 - 1e-05 25.4 1.1 0.0023 17.9 0.0 3.1 3 0 0 3 3 3 2 Formamidopyrimidine-DNA glycosylase H2TH domain Fungal_KA1 PF16797.5 AJA92191.1 - 0.079 12.7 2.1 0.36 10.5 2.4 2.0 2 0 0 2 2 2 0 Fungal kinase associated-1 domain adh_short PF00106.25 AJA92192.1 - 6.1e-59 198.8 0.7 7.8e-59 198.4 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AJA92192.1 - 5e-42 144.1 0.2 6e-42 143.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJA92192.1 - 1.1e-18 67.7 0.3 1.5e-18 67.3 0.3 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 AJA92192.1 - 2.6e-06 26.8 0.4 4e-06 26.2 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 AJA92192.1 - 6.2e-05 23.3 0.1 0.0001 22.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DFP PF04127.15 AJA92192.1 - 0.0003 20.7 0.2 0.00054 19.8 0.2 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NAD_binding_10 PF13460.6 AJA92192.1 - 0.00056 19.8 0.3 0.002 18.1 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 AJA92192.1 - 0.0012 18.4 0.1 0.0016 17.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AJA92192.1 - 0.0015 18.0 0.0 0.0039 16.6 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 AJA92192.1 - 0.002 18.0 1.6 0.0033 17.3 1.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pox_J1 PF03338.15 AJA92192.1 - 0.03 14.2 0.6 0.068 13.0 0.3 1.6 2 0 0 2 2 2 0 Poxvirus J1 protein Shikimate_DH PF01488.20 AJA92192.1 - 0.032 14.3 1.1 0.058 13.5 1.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Adenylsucc_synt PF00709.21 AJA92192.1 - 0.049 12.6 0.2 0.067 12.1 0.2 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase GDP_Man_Dehyd PF16363.5 AJA92192.1 - 0.057 12.8 0.1 0.077 12.4 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 AJA92192.1 - 0.071 12.5 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AJA92192.1 - 0.11 12.9 1.5 0.22 12.0 0.9 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding TP_methylase PF00590.20 AJA92192.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Wax2_C PF12076.8 AJA92192.1 - 0.15 11.8 0.4 0.22 11.2 0.4 1.2 1 0 0 1 1 1 0 WAX2 C-terminal domain QRPTase_C PF01729.19 AJA92193.1 - 1.7e-52 177.6 2.8 1.7e-52 177.6 2.8 1.4 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AJA92193.1 - 1.3e-25 89.3 0.3 3.2e-25 88.0 0.2 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ufm1 PF03671.14 AJA92193.1 - 0.027 14.6 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein TMP-TENI PF02581.17 AJA92193.1 - 0.032 13.6 0.1 0.057 12.7 0.1 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase Polyketide_cyc2 PF10604.9 AJA92194.1 - 4.7e-11 43.1 0.0 5.2e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FbpA PF05833.11 AJA92194.1 - 0.021 13.6 0.1 0.021 13.6 0.1 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) AA_kinase PF00696.28 AJA92195.1 - 4.7e-28 98.4 0.0 5.4e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family Copper-bind PF00127.20 AJA92196.1 - 3.2e-06 27.5 0.0 5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJA92196.1 - 0.049 13.7 0.0 0.076 13.1 0.0 1.5 1 1 0 1 1 1 0 Cupredoxin-like domain DUF4448 PF14610.6 AJA92196.1 - 0.057 13.2 1.9 0.11 12.2 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Peptidase_M3 PF01432.20 AJA92197.1 - 5.4e-43 147.9 0.2 1.4e-42 146.5 0.2 1.7 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 AJA92197.1 - 0.00057 20.1 1.6 0.0073 16.6 0.0 3.3 2 1 2 4 4 4 1 Oligopeptidase F Peptidase_M78 PF06114.13 AJA92197.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain Tho1_MOS11_C PF18592.1 AJA92197.1 - 0.058 13.2 0.9 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain MIT PF04212.18 AJA92197.1 - 0.083 13.0 0.1 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ECH_1 PF00378.20 AJA92198.1 - 7.6e-69 231.8 0.8 8.6e-69 231.6 0.8 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AJA92198.1 - 8.7e-41 140.5 0.3 1.2e-39 136.7 0.3 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF4362 PF14275.6 AJA92198.1 - 0.016 15.4 0.1 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) GHMP_kinases_C PF08544.13 AJA92199.1 - 1.6e-09 38.0 0.0 3.7e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 AJA92199.1 - 1.7e-05 25.0 0.1 2.9e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF3861 PF12977.7 AJA92199.1 - 0.033 14.4 0.0 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) HEM4 PF02602.15 AJA92200.1 - 2.3e-44 151.5 0.0 2.6e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD LEA_2 PF03168.13 AJA92201.1 - 0.063 13.8 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 Late embryogenesis abundant protein GXGXG PF01493.19 AJA92201.1 - 0.12 11.9 0.2 5.2 6.6 0.0 2.1 2 0 0 2 2 2 0 GXGXG motif PBP PF01161.20 AJA92202.1 - 2.5e-28 99.0 0.0 3.5e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Methyltransf_31 PF13847.6 AJA92203.1 - 2.4e-10 40.4 0.0 3.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 AJA92203.1 - 4.7e-10 39.3 0.5 2.3e-08 33.8 0.5 2.1 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 AJA92203.1 - 5.3e-10 39.9 0.0 1e-09 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJA92203.1 - 1.5e-07 32.0 0.0 2.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 AJA92203.1 - 0.00017 21.1 0.1 0.00028 20.4 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 AJA92203.1 - 0.00018 21.0 0.1 0.00025 20.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 AJA92203.1 - 0.00041 21.1 0.0 0.00065 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AJA92203.1 - 0.0006 19.0 0.0 0.00074 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 AJA92203.1 - 0.00076 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rsm22 PF09243.10 AJA92203.1 - 0.0013 18.1 0.1 0.0018 17.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 TehB PF03848.14 AJA92203.1 - 0.0033 16.9 0.1 0.0056 16.1 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB GidB PF02527.15 AJA92203.1 - 0.0038 16.6 0.1 0.0053 16.1 0.1 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 AJA92203.1 - 0.018 14.6 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 AJA92203.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Spb1_C PF07780.12 AJA92203.1 - 0.044 13.4 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 Spb1 C-terminal domain Ubie_methyltran PF01209.18 AJA92203.1 - 0.052 12.9 0.1 0.076 12.3 0.1 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 AJA92203.1 - 0.081 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_23 PF13489.6 AJA92203.1 - 0.087 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF5362 PF17319.2 AJA92203.1 - 0.098 12.5 0.1 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5362) MG2 PF01835.19 AJA92204.1 - 2.6e-05 24.6 0.0 3.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 MG2 domain FlgD_ig PF13860.6 AJA92204.1 - 0.036 13.9 0.1 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 FlgD Ig-like domain Pentapeptide PF00805.22 AJA92205.1 - 2.4e-71 234.8 64.0 5.9e-13 48.2 2.9 11.9 3 3 6 13 13 13 13 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AJA92205.1 - 1.1e-46 156.9 38.5 1.2e-08 34.9 0.3 7.1 3 1 6 9 9 9 8 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AJA92205.1 - 2.1e-32 111.0 15.2 6.5e-06 26.2 0.1 10.8 4 4 6 10 10 10 8 Pentapeptide repeats (9 copies) Lipase_GDSL_2 PF13472.6 AJA92205.1 - 5.9e-05 23.5 0.0 0.0001 22.7 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SIN1 PF05422.12 AJA92205.1 - 0.046 14.3 0.7 34 5.0 0.0 3.4 3 0 0 3 3 3 0 Stress-activated map kinase interacting protein 1 (SIN1) Glycos_transf_2 PF00535.26 AJA92206.1 - 3.4e-25 88.8 0.1 1e-24 87.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AJA92206.1 - 5.2e-11 42.9 0.0 1.1e-10 41.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AJA92206.1 - 3.3e-06 26.8 0.5 5.6e-06 26.0 0.3 1.4 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AJA92206.1 - 0.0012 19.4 0.0 0.0033 17.9 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 2 ABC_tran PF00005.27 AJA92207.1 - 2.3e-19 70.3 0.0 4.1e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AJA92207.1 - 3.7e-10 39.6 0.6 2e-05 24.2 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AJA92207.1 - 4.6e-09 36.5 0.2 0.0011 18.9 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AJA92207.1 - 0.00092 18.9 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 AJA92207.1 - 0.002 18.3 0.0 0.003 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AJA92207.1 - 0.0088 16.3 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AJA92207.1 - 0.011 16.3 0.2 0.32 11.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AJA92207.1 - 0.011 15.5 0.2 1.7 8.3 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 AJA92207.1 - 0.018 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AJA92207.1 - 0.028 14.0 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 AJA92207.1 - 0.033 12.8 1.6 0.24 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 AJA92207.1 - 0.074 12.4 0.1 8.9 5.6 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 AJA92207.1 - 0.094 12.8 0.0 0.28 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AJA92207.1 - 0.094 13.2 1.9 0.1 13.1 0.3 1.8 2 1 0 2 2 2 0 AAA domain MutS_V PF00488.21 AJA92207.1 - 0.1 12.6 0.2 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 MutS domain V RsgA_GTPase PF03193.16 AJA92207.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 AJA92207.1 - 0.13 12.7 0.0 0.9 10.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 AJA92207.1 - 0.14 12.6 0.1 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF4083 PF13314.6 AJA92208.1 - 0.45 10.5 3.8 2.2 8.3 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) NTP_transferase PF00483.23 AJA92209.1 - 7.7e-31 107.5 0.1 1.2e-30 106.9 0.1 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AJA92209.1 - 3.6e-14 53.4 0.0 5e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AJA92209.1 - 0.0003 20.6 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 AJA92209.1 - 0.0026 17.7 0.1 0.0034 17.3 0.1 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Glycos_transf_2 PF00535.26 AJA92209.1 - 0.0041 16.9 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 AJA92209.1 - 0.19 12.2 0.0 0.31 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 FixP_N PF14715.6 AJA92210.1 - 6.3 6.6 8.0 4.7 7.0 0.5 2.3 1 1 1 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Cpn60_TCP1 PF00118.24 AJA92211.1 - 9.4e-178 591.8 20.1 1.1e-177 591.6 20.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ustilago_mating PF05722.12 AJA92211.1 - 0.023 14.3 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Dak2 PF02734.17 AJA92211.1 - 0.043 13.7 5.6 1.3 8.9 0.2 2.9 2 1 0 2 2 2 0 DAK2 domain YbaB_DNA_bd PF02575.16 AJA92211.1 - 0.33 11.2 6.8 0.74 10.1 0.9 3.7 2 2 2 4 4 4 0 YbaB/EbfC DNA-binding family Methyltransf_21 PF05050.12 AJA92212.1 - 2.6e-18 66.7 0.1 3.7e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain PCMT PF01135.19 AJA92212.1 - 4.7e-08 33.0 0.0 6.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 AJA92212.1 - 2.3e-07 30.8 0.1 3.7e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Fibrillarin PF01269.17 AJA92212.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Sial-lect-inser PF09264.10 AJA92212.1 - 0.016 15.0 0.5 0.023 14.4 0.5 1.2 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion PrmA PF06325.13 AJA92212.1 - 0.017 14.5 0.1 0.025 14.0 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltr_RsmB-F PF01189.17 AJA92212.1 - 0.032 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PMT_2 PF13231.6 AJA92213.1 - 2.4e-08 34.3 16.9 2.4e-08 34.3 16.9 3.2 2 1 2 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Zds_C PF08632.10 AJA92213.1 - 0.11 12.3 0.5 0.42 10.4 0.3 2.1 2 0 0 2 2 2 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term zinc_ribbon_15 PF17032.5 AJA92214.1 - 0.0043 17.8 1.0 0.0045 17.7 1.0 1.0 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 AJA92214.1 - 0.013 15.6 1.8 0.03 14.3 1.9 1.6 1 1 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.13 AJA92214.1 - 0.014 15.0 4.1 1.6 8.5 0.2 2.3 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 AJA92214.1 - 0.016 14.9 1.3 3 7.7 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf_C2HC_14 PF18574.1 AJA92214.1 - 0.033 14.0 4.6 1.8 8.4 0.3 2.1 2 0 0 2 2 2 0 C2HC Zing finger domain HypA PF01155.19 AJA92214.1 - 0.034 14.2 0.8 0.042 13.9 0.8 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GFA PF04828.14 AJA92214.1 - 0.075 13.4 2.2 0.39 11.1 2.2 1.9 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf_UBZ PF18439.1 AJA92214.1 - 0.91 9.2 3.2 12 5.6 0.4 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger NAD_binding_1 PF00175.21 AJA92215.1 - 3.5e-13 50.1 0.0 5.3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AJA92215.1 - 2e-08 34.5 0.0 3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Methyltransf_34 PF11312.8 AJA92215.1 - 0.2 10.9 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Radical_SAM PF04055.21 AJA92216.1 - 7.7e-08 32.9 0.2 8.7e-07 29.5 0.0 2.6 3 0 0 3 3 3 1 Radical SAM superfamily B12-binding PF02310.19 AJA92216.1 - 4.5e-06 26.7 0.0 8.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain MATH PF00917.26 AJA92216.1 - 0.04 14.1 0.5 0.75 10.0 0.0 2.8 2 0 0 2 2 2 0 MATH domain Ribosomal_S6e PF01092.19 AJA92217.1 - 2.5e-27 95.3 0.5 3.2e-27 95.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S6e SNF2_N PF00176.23 AJA92219.1 - 5.8e-38 130.5 0.0 8.5e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AJA92219.1 - 6.4e-12 45.8 2.7 6.3e-11 42.6 0.1 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 AJA92219.1 - 0.00025 20.9 0.0 0.0007 19.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF445 PF04286.12 AJA92219.1 - 6.9 6.4 9.1 2.7 7.7 4.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF445) DUF359 PF04019.12 AJA92220.1 - 2.9e-35 120.6 0.0 3.9e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF359) N6_N4_Mtase PF01555.18 AJA92221.1 - 1.2e-37 129.8 4.8 1.5e-37 129.5 4.8 1.1 1 0 0 1 1 1 1 DNA methylase N6_Mtase PF02384.16 AJA92221.1 - 4.3e-05 22.9 0.1 0.0034 16.7 0.2 2.1 2 0 0 2 2 2 2 N-6 DNA Methylase UPF0020 PF01170.18 AJA92221.1 - 0.0001 22.0 0.0 0.18 11.5 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 N6-adenineMlase PF10237.9 AJA92221.1 - 0.026 14.3 0.1 0.053 13.3 0.1 1.7 1 1 0 1 1 1 0 Probable N6-adenine methyltransferase MTS PF05175.14 AJA92221.1 - 0.067 12.7 0.0 0.71 9.4 0.1 2.1 1 1 1 2 2 2 0 Methyltransferase small domain Pyr_redox_2 PF07992.14 AJA92222.1 - 3.4e-47 161.1 0.0 4.1e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJA92222.1 - 8.1e-15 55.1 1.0 1.7e-10 41.3 1.5 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AJA92222.1 - 0.0026 17.4 0.0 1.4 8.4 0.0 3.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 AJA92222.1 - 0.011 14.8 0.0 1.1 8.2 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A LSM14 PF12701.7 AJA92222.1 - 0.075 13.1 0.6 0.16 12.1 0.1 1.9 2 0 0 2 2 2 0 Scd6-like Sm domain NAD_binding_8 PF13450.6 AJA92222.1 - 0.096 12.9 0.0 18 5.6 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 AJA92222.1 - 0.11 11.3 0.0 7.4 5.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 AJA92222.1 - 0.15 11.1 0.0 4.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein EF1_GNE PF00736.19 AJA92223.1 - 6.3e-16 58.3 0.5 7.1e-16 58.2 0.5 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain DUF948 PF06103.11 AJA92223.1 - 0.14 12.4 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PALP PF00291.25 AJA92224.1 - 7.9e-68 229.0 0.4 9.1e-68 228.8 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme C1_2 PF03107.16 AJA92224.1 - 0.16 12.3 1.9 0.34 11.3 1.9 1.6 1 0 0 1 1 1 0 C1 domain tRNA-synt_2b PF00587.25 AJA92225.1 - 5.6e-19 68.8 0.0 3e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AJA92225.1 - 3e-18 65.7 1.2 9.8e-18 64.1 1.2 1.9 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.11 AJA92225.1 - 1.8e-16 60.1 2.2 6.5e-16 58.3 0.7 2.4 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal Apolipoprotein PF01442.18 AJA92226.1 - 0.00069 19.5 7.0 0.00091 19.2 3.6 2.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 AJA92226.1 - 0.0063 16.7 22.8 0.56 10.5 5.3 5.1 2 2 3 5 5 5 1 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 AJA92226.1 - 0.0074 16.6 1.0 0.0074 16.6 1.0 5.0 1 1 3 4 4 4 2 Syntaxin-like protein Nup54 PF13874.6 AJA92226.1 - 0.0099 16.0 8.8 0.074 13.2 0.1 3.0 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.12 AJA92226.1 - 0.033 14.2 1.1 0.033 14.2 1.1 4.0 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus BRX_N PF13713.6 AJA92226.1 - 0.042 13.6 1.8 3.2 7.6 0.1 3.6 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain DUF1664 PF07889.12 AJA92226.1 - 0.043 13.9 31.0 0.17 11.9 4.6 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 AJA92226.1 - 0.047 13.5 28.5 0.15 11.9 4.3 3.9 1 1 3 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TolA_bind_tri PF16331.5 AJA92226.1 - 0.1 12.7 17.2 3.7 7.7 0.5 4.9 3 2 1 4 4 4 0 TolA binding protein trimerisation Syntaxin-6_N PF09177.11 AJA92226.1 - 0.4 11.3 15.4 0.74 10.4 0.8 4.2 1 1 3 4 4 4 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 AJA92226.1 - 0.51 10.4 22.6 10 6.2 0.9 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 AJA92226.1 - 0.68 10.1 34.9 0.033 14.4 2.9 3.7 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family Sec34 PF04136.15 AJA92226.1 - 1.2 9.1 22.4 2.2 8.1 0.4 5.1 1 1 5 7 7 7 0 Sec34-like family Laminin_II PF06009.12 AJA92226.1 - 1.3 9.1 31.6 0.054 13.5 5.3 4.2 1 1 3 4 4 4 0 Laminin Domain II PIN_8 PF18476.1 AJA92226.1 - 1.6 8.6 24.9 3.4 7.5 2.4 3.5 1 1 2 3 3 3 0 PIN like domain DUF3450 PF11932.8 AJA92226.1 - 1.7 7.9 25.3 0.54 9.5 0.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF1515 PF07439.11 AJA92226.1 - 1.8 8.6 19.4 0.62 10.1 1.1 4.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1515) SlyX PF04102.12 AJA92226.1 - 2.3 8.9 11.8 49 4.6 0.2 5.2 3 2 2 5 5 5 0 SlyX DUF2205 PF10224.9 AJA92226.1 - 6 6.9 12.0 1.8 8.6 0.5 4.2 1 1 2 4 4 4 0 Short coiled-coil protein eIF3_N PF09440.10 AJA92227.1 - 0.012 16.1 1.3 0.044 14.2 0.2 1.9 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Radial_spoke PF04712.12 AJA92227.1 - 0.072 12.0 0.5 0.087 11.8 0.5 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein DUF3445 PF11927.8 AJA92229.1 - 0.054 13.1 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) TetR_C_2 PF08361.11 AJA92229.1 - 0.094 12.8 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region DEAD PF00270.29 AJA92230.1 - 2.8e-37 128.2 0.1 6.1e-37 127.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AJA92230.1 - 9.1e-22 77.5 0.7 7e-19 68.2 0.1 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD_assoc PF08494.11 AJA92230.1 - 5.6e-19 68.7 0.0 3.6e-18 66.0 0.0 2.2 1 1 0 1 1 1 1 DEAD/H associated ResIII PF04851.15 AJA92230.1 - 7.1e-15 55.4 0.1 2.6e-14 53.6 0.1 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SpoU_sub_bind PF08032.12 AJA92230.1 - 0.00027 21.2 2.0 0.028 14.7 0.0 3.6 3 0 0 3 3 3 1 RNA 2'-O ribose methyltransferase substrate binding AAA_19 PF13245.6 AJA92230.1 - 0.00027 21.3 0.1 0.001 19.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.23 AJA92230.1 - 0.00044 19.1 0.0 0.00083 18.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 AJA92230.1 - 0.017 15.4 1.1 0.12 12.7 0.2 2.5 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 AJA92230.1 - 0.062 12.7 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein UvrD-helicase PF00580.21 AJA92230.1 - 0.16 11.4 4.8 0.1 12.1 0.7 2.7 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Clc-like PF07062.12 AJA92230.1 - 0.18 11.3 0.3 0.31 10.5 0.3 1.3 1 0 0 1 1 1 0 Clc-like DNA_pol_E_B PF04042.16 AJA92231.1 - 3.1e-22 79.0 0.0 5.4e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos PF00149.28 AJA92231.1 - 8.7e-13 49.2 0.1 1.7e-12 48.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AJA92231.1 - 1.8e-09 38.0 0.0 4.4e-08 33.5 0.0 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain tRNA_anti-codon PF01336.25 AJA92231.1 - 0.094 12.7 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Nitroreductase PF00881.24 AJA92232.1 - 2.2e-25 89.7 0.0 4.7e-25 88.6 0.0 1.5 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AJA92232.1 - 0.023 14.3 0.8 0.27 10.8 0.0 2.4 2 1 1 3 3 3 0 Putative TM nitroreductase Arginosuc_synth PF00764.19 AJA92233.1 - 2.1e-159 531.0 0.2 2.4e-159 530.8 0.2 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.21 AJA92233.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 AJA92233.1 - 0.00013 21.6 0.1 0.00029 20.4 0.1 1.6 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AJA92233.1 - 0.12 12.1 0.2 0.34 10.7 0.1 1.8 1 1 1 2 2 2 0 PP-loop family Nre_N PF04894.12 AJA92234.1 - 5.6e-87 292.0 0.0 7.9e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Archaeal Nre, N-terminal Nre_C PF04895.12 AJA92234.1 - 1.2e-34 118.5 0.0 2.1e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal Nre, C-terminal PRA-CH PF01502.18 AJA92235.1 - 6.2e-33 112.5 0.1 7.8e-33 112.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase FeS_assembly_P PF01883.19 AJA92236.1 - 1.7e-17 63.4 0.2 3.3e-17 62.4 0.2 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein PqqD PF05402.12 AJA92236.1 - 1.3e-09 38.2 0.0 2.3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) HemN_C PF06969.16 AJA92236.1 - 0.007 16.4 0.3 0.015 15.4 0.1 1.6 2 0 0 2 2 2 1 HemN C-terminal domain DUF4252 PF14060.6 AJA92236.1 - 0.0085 16.0 0.8 4 7.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4252) DUF4777 PF16007.5 AJA92236.1 - 0.071 13.4 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) NeuB PF03102.14 AJA92237.1 - 1.1e-77 260.8 0.2 1.3e-77 260.5 0.2 1.1 1 0 0 1 1 1 1 NeuB family TraF PF13728.6 AJA92237.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein PHP_C PF13263.6 AJA92238.1 - 8.7e-14 51.0 0.0 3.5e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 PHP-associated PHP PF02811.19 AJA92238.1 - 0.015 15.6 3.1 0.026 14.8 3.1 1.4 1 1 0 1 1 1 0 PHP domain DUF5621 PF18532.1 AJA92238.1 - 0.036 14.0 4.3 0.07 13.0 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) 7TM_GPCR_Sri PF10327.9 AJA92238.1 - 0.057 12.6 1.0 0.092 11.9 1.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Sigma70_r1_1 PF03979.14 AJA92238.1 - 0.17 12.0 2.5 11 6.2 0.2 3.0 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 Putative_PNPOx PF01243.20 AJA92239.1 - 1.1e-15 57.5 0.0 1.4e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.12 AJA92239.1 - 0.0073 16.1 0.0 0.0081 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Pyrid_ox_like PF16242.5 AJA92239.1 - 0.027 14.1 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like UvrC_HhH_N PF08459.11 AJA92240.1 - 5.2e-48 162.9 0.6 1.4e-47 161.4 0.0 2.0 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.24 AJA92240.1 - 4.4e-12 46.1 1.8 1.5e-11 44.4 1.8 2.0 1 0 0 1 1 1 1 GIY-YIG catalytic domain UVR PF02151.19 AJA92240.1 - 7.9e-10 38.2 0.8 3e-09 36.3 0.8 2.1 1 0 0 1 1 1 1 UvrB/uvrC motif DUF3067 PF11267.8 AJA92240.1 - 0.013 16.1 0.3 2 9.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) DUF1106 PF06523.11 AJA92240.1 - 0.17 12.0 1.1 5 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1106) PP-binding PF00550.25 AJA92241.1 - 8.3e-05 22.9 0.0 9.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF111 PF01969.17 AJA92242.1 - 1.8e-106 356.4 0.6 2e-106 356.2 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 Radical_SAM_C PF16199.5 AJA92243.1 - 4.4e-25 87.5 0.4 9.2e-25 86.5 0.4 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 AJA92243.1 - 1.9e-21 77.2 0.0 5.1e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_10 PF13673.7 AJA92243.1 - 5.9e-06 26.2 0.1 1.4e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AJA92243.1 - 0.0024 18.1 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AJA92243.1 - 0.015 15.7 0.0 0.037 14.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4777 PF16007.5 AJA92243.1 - 0.03 14.6 0.2 0.82 10.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) Copper-bind PF00127.20 AJA92244.1 - 1.4e-07 31.9 0.1 3.9e-07 30.4 0.1 1.8 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJA92244.1 - 0.00042 20.4 0.0 0.00059 19.9 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain DUF4884 PF16225.5 AJA92244.1 - 0.38 10.9 2.8 0.35 11.0 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4884) TP6A_N PF04406.14 AJA92245.1 - 1.2e-13 50.8 0.1 2.3e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Toprim PF01751.22 AJA92245.1 - 0.085 13.1 0.9 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Toprim domain SPATA48 PF15073.6 AJA92245.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 SLIDE PF09111.10 AJA92246.1 - 0.034 14.2 0.9 0.16 12.0 0.2 2.5 1 1 2 3 3 3 0 SLIDE HD PF01966.22 AJA92247.1 - 2.2e-13 50.5 0.9 2.7e-13 50.2 0.2 1.5 2 0 0 2 2 2 1 HD domain Prok_Ub PF14454.6 AJA92247.1 - 0.088 12.5 0.1 8.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic Ubiquitin Nuclease_act PF08133.11 AJA92247.1 - 0.14 12.4 1.2 0.4 10.9 0.1 2.4 2 0 0 2 2 2 0 Anticodon nuclease activator family DUF5636 PF18686.1 AJA92247.1 - 2.4 8.3 7.9 2.7 8.2 1.9 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5636) TPR_1 PF00515.28 AJA92248.1 - 5.9e-06 25.9 0.3 0.0066 16.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AJA92248.1 - 0.00016 21.5 0.2 0.44 10.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AJA92248.1 - 0.0029 18.1 0.0 0.69 10.5 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF4919 PF16266.5 AJA92248.1 - 0.016 15.2 0.6 1.3 8.9 0.2 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4919) Fis1_TPR_C PF14853.6 AJA92248.1 - 0.024 14.7 3.3 2.9 8.0 0.1 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF3638 PF12340.8 AJA92248.1 - 0.082 12.2 0.3 0.1 11.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) TPR_15 PF13429.6 AJA92248.1 - 0.095 11.9 0.0 0.21 10.8 0.0 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 AJA92248.1 - 0.16 12.9 0.0 54 5.0 0.0 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat Homoserine_dh PF00742.19 AJA92249.1 - 2.3e-52 177.4 0.3 3.5e-52 176.8 0.3 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase ELFV_dehydrog PF00208.21 AJA92249.1 - 1.7e-08 34.5 0.0 3.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_3 PF03447.16 AJA92249.1 - 6.1e-06 26.9 0.0 1.5e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain COX2 PF00116.20 AJA92250.1 - 1.8e-16 60.1 0.5 4.5e-13 49.1 0.0 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.6 AJA92250.1 - 1.1e-06 28.7 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain PRMT5_C PF17286.2 AJA92250.1 - 0.079 12.8 0.5 0.11 12.4 0.1 1.4 1 1 0 1 1 1 0 PRMT5 oligomerisation domain RNA_pol_Rpb6 PF01192.22 AJA92251.1 - 1.2e-10 41.1 0.0 2.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb6 Fib_alpha PF08702.10 AJA92252.1 - 0.019 15.1 1.7 0.051 13.8 1.8 1.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FliD_C PF07195.12 AJA92252.1 - 0.019 14.4 2.0 0.023 14.1 2.0 1.0 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF641 PF04859.12 AJA92252.1 - 0.02 15.2 0.5 0.026 14.9 0.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) GIT1_C PF12205.8 AJA92252.1 - 0.023 14.8 0.2 0.045 13.9 0.2 1.5 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Fe_dep_repress PF01325.19 AJA92253.1 - 7.6e-16 58.1 0.1 1.5e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.15 AJA92253.1 - 6.6e-15 54.9 0.0 1.2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain HTH_27 PF13463.6 AJA92253.1 - 5.3e-06 26.8 0.1 9.1e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 AJA92253.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AJA92253.1 - 1.2e-05 25.1 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AJA92253.1 - 8.4e-05 22.8 0.0 0.00035 20.9 0.1 1.9 2 0 0 2 2 2 1 Transcriptional regulator TrmB PF01978.19 AJA92253.1 - 0.0009 19.1 0.1 0.0014 18.5 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AJA92253.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 AJA92253.1 - 0.0039 17.0 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.7 AJA92253.1 - 0.025 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 AJA92253.1 - 0.035 14.0 0.1 0.093 12.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_45 PF14947.6 AJA92253.1 - 0.046 13.7 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DUF2250 PF10007.9 AJA92253.1 - 0.057 13.5 0.2 0.085 13.0 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) NLPC_P60 PF00877.19 AJA92253.1 - 0.17 11.9 0.0 0.71 9.9 0.0 1.8 2 0 0 2 2 2 0 NlpC/P60 family AHSA1 PF08327.11 AJA92254.1 - 1.2e-06 28.8 0.1 1.9e-06 28.1 0.0 1.4 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 AJA92254.1 - 1.3e-06 28.7 0.0 1.9e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AJA92254.1 - 1.8e-06 28.2 0.0 3.4e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport IGPD PF00475.18 AJA92255.1 - 7.5e-47 159.3 1.3 9.4e-47 158.9 1.3 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF916 PF06030.12 AJA92255.1 - 0.021 14.9 0.2 0.15 12.2 0.0 2.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF916) Histidinol_dh PF00815.20 AJA92256.1 - 4.6e-132 440.9 2.6 5.2e-132 440.7 2.6 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase T_Ag_DNA_bind PF02217.16 AJA92256.1 - 0.035 14.7 0.1 0.1 13.2 0.1 1.9 1 0 0 1 1 1 0 Origin of replication binding protein SLS PF14611.6 AJA92256.1 - 0.76 9.6 6.1 0.76 9.6 0.5 2.2 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Lipoprotein_20 PF13942.6 AJA92256.1 - 3.1 7.7 6.6 3.3 7.6 2.3 2.2 2 0 0 2 2 2 0 YfhG lipoprotein Aminotran_1_2 PF00155.21 AJA92257.1 - 4.9e-60 203.6 0.0 7e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II CM_2 PF01817.21 AJA92257.1 - 1.4e-10 41.3 1.1 3.3e-10 40.2 1.1 1.7 1 0 0 1 1 1 1 Chorismate mutase type II Aminotran_5 PF00266.19 AJA92257.1 - 5e-07 29.0 0.0 1.7e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AJA92257.1 - 9.9e-05 21.8 0.0 0.00032 20.1 0.0 1.8 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AJA92257.1 - 0.0004 19.0 0.0 0.00082 18.0 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AJA92257.1 - 0.017 14.4 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase bZIP_1 PF00170.21 AJA92257.1 - 3.8 7.7 5.3 2 8.5 0.7 2.7 2 0 0 2 2 2 0 bZIP transcription factor OrfB_Zn_ribbon PF07282.11 AJA92259.1 - 0.13 12.2 8.4 2.6 8.1 8.8 2.0 1 1 0 1 1 1 0 Putative transposase DNA-binding domain UvrA_inter PF17760.1 AJA92260.1 - 1.2e-34 118.7 1.0 4.3e-34 116.9 1.0 2.1 1 0 0 1 1 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 AJA92260.1 - 2.8e-34 117.8 0.6 4e-32 110.8 0.3 3.2 3 0 0 3 3 2 1 UvrA DNA-binding domain ABC_tran PF00005.27 AJA92260.1 - 3.1e-24 86.0 0.2 3.7e-10 40.5 0.0 4.5 3 1 0 3 3 3 3 ABC transporter SMC_N PF02463.19 AJA92260.1 - 1.1e-09 38.1 3.1 0.031 13.7 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AJA92260.1 - 1.9e-08 34.5 1.0 0.12 12.1 0.1 4.7 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AJA92260.1 - 1.2e-07 32.2 0.0 0.033 14.6 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 AJA92260.1 - 2.7e-07 30.2 0.5 0.039 13.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AJA92260.1 - 3e-06 27.2 3.2 0.043 13.7 0.1 3.3 4 0 0 4 4 3 2 RsgA GTPase AAA_14 PF13173.6 AJA92260.1 - 3.1e-05 24.0 0.0 0.19 11.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 AJA92260.1 - 0.00012 21.4 0.2 0.65 9.1 0.0 3.6 4 0 0 4 4 3 2 NB-ARC domain AAA_22 PF13401.6 AJA92260.1 - 0.00012 22.4 4.3 0.49 10.7 0.0 4.5 5 1 0 5 5 4 2 AAA domain AAA_33 PF13671.6 AJA92260.1 - 0.00013 22.2 0.2 0.55 10.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain APS_kinase PF01583.20 AJA92260.1 - 0.00014 21.8 0.3 0.77 9.6 0.1 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_18 PF13238.6 AJA92260.1 - 0.00017 22.1 1.1 1 9.9 0.1 4.0 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.6 AJA92260.1 - 0.00037 20.1 0.1 0.7 9.4 0.0 3.3 4 0 0 4 4 3 1 AAA domain Viral_helicase1 PF01443.18 AJA92260.1 - 0.00048 19.9 0.0 0.058 13.1 0.1 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 AJA92260.1 - 0.00064 19.1 0.1 0.55 9.5 0.0 2.8 2 0 0 2 2 2 2 KaiC T2SSE PF00437.20 AJA92260.1 - 0.001 18.2 0.1 1.1 8.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein cobW PF02492.19 AJA92260.1 - 0.0011 18.6 1.3 0.5 9.9 0.3 3.0 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 AJA92260.1 - 0.0014 18.5 0.1 1 9.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 AJA92260.1 - 0.0041 17.2 0.6 0.48 10.5 0.1 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 AJA92260.1 - 0.0078 16.1 4.6 0.83 9.5 0.5 3.6 3 1 0 3 3 2 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 AJA92260.1 - 0.009 15.3 0.9 2.9 7.0 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 AJA92260.1 - 0.015 14.6 0.1 4.1 6.6 0.0 3.1 4 0 0 4 4 4 0 Zeta toxin AAA_7 PF12775.7 AJA92260.1 - 0.016 14.7 0.2 3.5 7.1 0.1 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region RNA_helicase PF00910.22 AJA92260.1 - 0.017 15.5 0.1 7.2 7.1 0.0 3.2 3 0 0 3 3 2 0 RNA helicase DnaJ_CXXCXGXG PF00684.19 AJA92260.1 - 0.018 15.4 0.4 0.018 15.4 0.4 4.0 4 1 0 4 4 3 0 DnaJ central domain NTPase_1 PF03266.15 AJA92260.1 - 0.022 14.7 2.5 0.85 9.5 0.1 3.8 4 0 0 4 4 4 0 NTPase Ssu72 PF04722.13 AJA92260.1 - 0.023 14.3 0.3 0.34 10.4 0.0 2.3 2 0 0 2 2 2 0 Ssu72-like protein MeaB PF03308.16 AJA92260.1 - 0.033 13.2 0.0 1.2 8.1 0.0 2.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 AJA92260.1 - 0.055 13.2 0.1 17 5.0 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 AJA92260.1 - 0.066 13.7 0.1 0.066 13.7 0.1 3.9 4 1 0 4 4 3 0 AAA domain PRK PF00485.18 AJA92260.1 - 0.072 12.8 0.2 2.4 7.8 0.1 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 AJA92260.1 - 0.14 12.4 0.3 30 4.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AJA92260.1 - 0.14 11.8 15.5 0.15 11.8 0.3 4.5 4 1 0 4 4 4 0 AAA ATPase domain zinc_ribbon_2 PF13240.6 AJA92260.1 - 0.15 11.8 3.7 3.3 7.5 0.3 2.9 2 0 0 2 2 2 0 zinc-ribbon domain AAA_24 PF13479.6 AJA92260.1 - 0.18 11.5 4.8 26 4.5 0.0 4.1 4 0 0 4 4 4 0 AAA domain Amidohydro_1 PF01979.20 AJA92261.1 - 7.4e-19 68.3 0.1 1.9e-15 57.1 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 AJA92261.1 - 1.1e-14 54.9 0.0 1.5e-08 34.6 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family NAD_binding_1 PF00175.21 AJA92263.1 - 7e-10 39.5 0.0 2.5e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.9 AJA92263.1 - 5.3e-09 35.7 6.4 1.1e-08 34.7 6.4 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.24 AJA92263.1 - 0.0068 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_8 PF08022.12 AJA92263.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 FAD-binding domain AAA PF00004.29 AJA92264.1 - 7e-100 330.7 0.2 3.1e-49 166.8 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 AJA92264.1 - 1.6e-29 101.9 0.1 5.9e-29 100.1 0.1 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_lid_3 PF17862.1 AJA92264.1 - 1e-19 70.0 2.0 3.1e-11 42.9 0.0 3.3 2 1 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 AJA92264.1 - 4.6e-16 59.4 0.2 4e-07 30.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 AJA92264.1 - 4.3e-15 55.8 0.0 7.8e-09 35.5 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AJA92264.1 - 6e-15 56.0 0.1 7.4e-06 26.5 0.0 3.5 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 AJA92264.1 - 1e-10 41.4 0.1 0.00014 21.2 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 AJA92264.1 - 4.5e-10 39.9 0.4 0.0026 18.0 0.0 4.1 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.6 AJA92264.1 - 2.3e-09 37.6 0.0 0.002 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 AJA92264.1 - 2.8e-09 37.1 0.0 0.0013 18.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 AJA92264.1 - 3e-09 37.0 0.8 0.0012 18.8 0.1 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 AJA92264.1 - 9e-09 35.0 0.1 2.3e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 AJA92264.1 - 2.1e-07 30.8 0.0 0.0079 16.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 AJA92264.1 - 2.5e-07 30.6 0.1 0.052 13.2 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 AJA92264.1 - 1.3e-06 28.7 0.0 0.046 14.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ATPase PF06745.13 AJA92264.1 - 1.8e-06 27.5 1.3 0.11 11.8 0.0 3.7 3 1 1 4 4 3 2 KaiC AAA_7 PF12775.7 AJA92264.1 - 2.1e-06 27.4 0.0 0.036 13.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 AJA92264.1 - 3.2e-06 27.7 0.1 0.029 14.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain Bac_DnaA PF00308.18 AJA92264.1 - 3.4e-06 27.1 0.0 0.0014 18.5 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein TsaE PF02367.17 AJA92264.1 - 7.3e-06 26.0 0.1 0.19 11.7 0.0 2.7 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AJA92264.1 - 1.2e-05 25.1 0.0 0.036 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 AJA92264.1 - 1.4e-05 25.4 0.1 0.027 14.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AJA92264.1 - 1.7e-05 24.3 1.2 0.041 13.3 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI PhoH PF02562.16 AJA92264.1 - 5.8e-05 22.6 0.2 0.36 10.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Zeta_toxin PF06414.12 AJA92264.1 - 0.00011 21.5 0.1 0.15 11.3 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin ATPase_2 PF01637.18 AJA92264.1 - 0.00014 21.9 1.0 0.068 13.1 0.0 4.0 3 2 1 4 4 4 1 ATPase domain predominantly from Archaea NACHT PF05729.12 AJA92264.1 - 0.0002 21.3 0.1 1.7 8.5 0.0 3.5 4 0 0 4 4 4 2 NACHT domain DUF815 PF05673.13 AJA92264.1 - 0.00031 20.0 0.0 0.12 11.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 AJA92264.1 - 0.00031 21.3 0.0 0.83 10.2 0.0 2.6 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 AJA92264.1 - 0.00033 19.9 0.0 0.45 9.7 0.0 2.8 3 0 0 3 3 2 2 NB-ARC domain AAA_30 PF13604.6 AJA92264.1 - 0.00064 19.5 0.4 1.6 8.4 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 AJA92264.1 - 0.00071 19.4 0.0 0.53 10.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 AJA92264.1 - 0.001 18.8 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase DUF2075 PF09848.9 AJA92264.1 - 0.0016 17.8 0.3 0.4 9.9 0.0 2.6 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 AJA92264.1 - 0.0018 17.4 0.0 0.32 10.1 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 AJA92264.1 - 0.0042 16.9 0.8 0.71 9.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 AJA92264.1 - 0.0069 16.4 0.0 2.2 8.3 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 AJA92264.1 - 0.0073 16.4 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Guanylate_kin PF00625.21 AJA92264.1 - 0.0074 16.0 0.1 5.8 6.6 0.0 3.6 3 1 1 4 4 3 0 Guanylate kinase Vps4_C PF09336.10 AJA92264.1 - 0.011 15.7 2.5 3.9 7.6 0.5 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain NTPase_1 PF03266.15 AJA92264.1 - 0.012 15.5 0.4 10 6.0 0.0 3.8 2 1 1 3 3 3 0 NTPase AAA_25 PF13481.6 AJA92264.1 - 0.015 14.9 10.1 1.4 8.5 0.2 4.5 2 2 2 5 5 5 0 AAA domain AAA_17 PF13207.6 AJA92264.1 - 0.016 15.7 0.6 1.2 9.5 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 AJA92264.1 - 0.018 14.8 0.1 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain CPT PF07931.12 AJA92264.1 - 0.019 14.8 0.0 2.8 7.8 0.0 2.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 AJA92264.1 - 0.024 14.0 0.0 6.6 6.1 0.0 2.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 AJA92264.1 - 0.026 14.9 2.6 3.6 7.9 0.1 3.7 3 1 1 4 4 3 0 AAA domain Rad17 PF03215.15 AJA92264.1 - 0.03 14.2 0.0 11 5.9 0.0 3.1 2 1 1 3 3 3 0 Rad17 P-loop domain T2SSE PF00437.20 AJA92264.1 - 0.033 13.3 0.0 8 5.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.16 AJA92264.1 - 0.064 12.6 0.1 13 5.1 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase Viral_helicase1 PF01443.18 AJA92264.1 - 0.067 12.9 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AFG1_ATPase PF03969.16 AJA92264.1 - 0.077 11.9 0.0 12 4.6 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase ATP-synt_ab PF00006.25 AJA92264.1 - 0.083 12.5 0.0 6.4 6.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 AJA92264.1 - 0.16 11.7 0.0 23 4.7 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Torsin PF06309.11 AJA92264.1 - 0.21 11.7 0.1 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Torsin polyprenyl_synt PF00348.17 AJA92265.1 - 1.4e-71 240.5 0.2 1.8e-71 240.2 0.2 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 AJA92265.1 - 8e-05 22.1 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HEPPP_synt_1 PF07307.11 AJA92265.1 - 0.004 16.8 0.1 0.0071 16.0 0.1 1.4 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 TPR_1 PF00515.28 AJA92266.1 - 6.5e-52 171.3 15.0 3.4e-08 33.0 0.0 8.2 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.17 AJA92266.1 - 1.5e-47 155.9 6.8 6.4e-06 25.9 0.0 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 AJA92266.1 - 2.3e-37 124.1 9.2 0.00011 22.2 0.1 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 AJA92266.1 - 2.7e-36 121.3 11.9 2.6e-05 24.3 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 AJA92266.1 - 3.7e-34 116.9 6.9 6.4e-11 42.4 0.0 6.3 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 AJA92266.1 - 2e-33 113.8 11.6 5e-09 35.7 0.1 8.1 3 2 5 8 8 8 6 TPR repeat TPR_16 PF13432.6 AJA92266.1 - 2.7e-31 107.9 0.0 2.5e-10 40.8 0.0 5.1 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 AJA92266.1 - 3e-29 99.2 0.0 3.7e-05 24.2 0.1 7.8 1 1 7 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 AJA92266.1 - 1.2e-28 99.4 5.8 8e-09 35.9 0.3 5.1 3 1 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AJA92266.1 - 1.2e-23 83.1 7.6 1.6e-11 44.3 0.0 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 AJA92266.1 - 8.7e-22 75.5 0.1 0.0021 18.0 0.0 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 AJA92266.1 - 3.5e-21 74.4 1.2 0.065 13.9 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 AJA92266.1 - 3.8e-17 62.2 0.0 2.4e-06 27.6 0.0 4.8 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_20 PF14561.6 AJA92266.1 - 1e-13 51.4 7.7 0.0095 16.3 0.0 6.0 2 1 5 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 AJA92266.1 - 1.7e-12 46.8 4.5 0.00078 19.2 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat Coatomer_E PF04733.14 AJA92266.1 - 2.6e-10 40.2 9.0 0.0061 16.0 0.1 4.5 1 1 4 5 5 5 4 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 AJA92266.1 - 4.7e-10 39.4 9.0 0.0054 16.8 0.0 7.1 6 3 2 8 8 8 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 AJA92266.1 - 9.1e-09 34.8 0.8 3.2e-05 23.1 0.0 2.4 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 AJA92266.1 - 1.1e-06 28.1 1.1 0.00051 19.3 0.1 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AJA92266.1 - 2.1e-06 28.3 2.0 0.018 15.5 0.0 3.6 4 0 0 4 4 4 2 Alkyl sulfatase dimerisation DUF4919 PF16266.5 AJA92266.1 - 8.6e-06 25.8 14.0 1.5 8.8 0.0 5.3 1 1 4 5 5 5 2 Domain of unknown function (DUF4919) Rapsyn_N PF10579.9 AJA92266.1 - 1.4e-05 25.1 0.1 0.36 10.9 0.0 4.2 3 1 1 4 4 4 1 Rapsyn N-terminal myristoylation and linker region TPR_21 PF09976.9 AJA92266.1 - 3.3e-05 23.7 2.7 0.015 15.0 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 AJA92266.1 - 8e-05 23.1 0.0 0.012 16.1 0.0 3.0 1 1 3 4 4 4 2 Bacterial transcriptional activator domain DUF3856 PF12968.7 AJA92266.1 - 9.5e-05 22.5 0.2 3.4 7.7 0.0 4.5 3 1 2 5 5 4 1 Domain of Unknown Function (DUF3856) RPN6_N PF18055.1 AJA92266.1 - 0.00031 21.1 4.7 0.09 13.1 0.1 4.4 3 2 1 4 4 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_3 PF07720.12 AJA92266.1 - 0.00047 20.1 11.4 0.41 10.7 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_5 PF12688.7 AJA92266.1 - 0.00053 20.2 0.0 3.9 7.7 0.0 3.4 2 1 0 3 3 3 1 Tetratrico peptide repeat TPR_4 PF07721.14 AJA92266.1 - 0.0014 19.0 0.0 0.39 11.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Sel1 PF08238.12 AJA92266.1 - 0.0015 19.1 0.1 17 6.2 0.0 4.1 4 0 0 4 4 3 0 Sel1 repeat PknG_TPR PF16918.5 AJA92266.1 - 0.0038 16.0 0.0 1.2 7.8 0.0 2.7 2 1 2 4 4 4 1 Protein kinase G tetratricopeptide repeat TOM20_plant PF06552.12 AJA92266.1 - 0.017 14.9 11.9 4.6 6.9 0.1 5.1 2 1 2 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 SPO22 PF08631.10 AJA92266.1 - 0.021 14.3 3.0 12 5.2 0.0 4.3 4 1 1 5 5 5 0 Meiosis protein SPO22/ZIP4 like HrpB1_HrpK PF09613.10 AJA92266.1 - 0.051 13.2 0.0 1.9 8.2 0.0 2.8 2 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) COP23 PF14218.6 AJA92266.1 - 0.082 12.7 0.3 5.3 6.8 0.1 2.9 2 1 0 2 2 2 0 Circadian oscillating protein COP23 PPR PF01535.20 AJA92266.1 - 0.14 12.4 5.8 40 4.8 0.1 5.3 6 0 0 6 6 5 0 PPR repeat DUF2796 PF10986.8 AJA92266.1 - 0.77 9.7 13.4 0.52 10.2 11.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) Zip PF02535.22 AJA92266.1 - 1.1 8.4 2.8 1.4 8.1 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 AJA92266.1 - 1.3 8.4 12.0 2.2 7.6 12.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TPR_1 PF00515.28 AJA92267.1 - 7.4e-31 104.7 4.6 7.5e-10 38.2 0.0 4.0 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 AJA92267.1 - 2.6e-25 86.4 2.9 5.5e-07 29.2 0.0 4.0 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 AJA92267.1 - 1.7e-20 71.5 6.3 1.8e-05 24.6 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 AJA92267.1 - 5.3e-19 67.6 4.2 7.5e-08 31.9 0.0 3.2 2 1 1 3 3 3 3 TPR repeat TPR_17 PF13431.6 AJA92267.1 - 5.9e-17 60.8 1.1 1.2e-08 34.7 0.0 3.7 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AJA92267.1 - 2e-15 56.8 1.3 0.0031 17.7 0.0 3.9 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 AJA92267.1 - 1.1e-13 51.6 0.0 8.5e-07 29.5 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AJA92267.1 - 1.3e-12 46.8 0.6 0.0082 16.1 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 AJA92267.1 - 2.1e-12 47.4 0.7 1.3e-07 32.0 0.0 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 AJA92267.1 - 8.3e-10 38.7 0.1 9.9e-05 22.9 0.0 3.6 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 AJA92267.1 - 5.4e-07 29.3 0.5 0.082 12.8 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 AJA92267.1 - 3.2e-06 26.4 1.8 6.9e-05 21.9 0.1 2.0 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 AJA92267.1 - 3.4e-06 27.1 0.0 7.7e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 AJA92267.1 - 3.5e-06 27.3 0.5 4.7 8.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 AJA92267.1 - 1.2e-05 25.3 1.3 0.058 13.4 0.2 2.3 1 1 1 2 2 2 2 Putative TPR-like repeat ANAPC3 PF12895.7 AJA92267.1 - 4e-05 23.8 1.4 7.6e-05 22.9 0.6 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 AJA92267.1 - 8.4e-05 22.6 8.5 0.15 12.2 0.6 3.4 2 2 1 3 3 3 2 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 AJA92267.1 - 0.0054 16.2 0.4 4.7 6.7 0.1 3.2 3 0 0 3 3 3 1 SHNi-TPR Coatomer_E PF04733.14 AJA92267.1 - 0.0061 16.0 0.2 0.012 15.1 0.1 1.4 1 1 0 1 1 1 1 Coatomer epsilon subunit DUF3856 PF12968.7 AJA92267.1 - 0.0064 16.6 0.5 1.2 9.2 0.0 3.3 1 1 2 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_15 PF13429.6 AJA92267.1 - 0.013 14.8 0.3 0.028 13.6 0.3 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 AJA92267.1 - 0.02 15.1 1.7 0.61 10.3 0.0 3.2 1 1 3 4 4 4 0 MIT domain of nuclear receptor-binding factor 2 FAT PF02259.23 AJA92267.1 - 0.023 13.9 0.4 0.096 11.9 0.4 1.8 1 1 0 1 1 1 0 FAT domain DUF357 PF04010.13 AJA92267.1 - 0.025 14.7 1.7 0.47 10.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF357) SNAP PF14938.6 AJA92267.1 - 0.08 12.4 5.7 0.17 11.3 0.7 2.5 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP NSF PF02071.20 AJA92267.1 - 0.33 11.9 2.5 1.5e+02 3.9 0.1 3.9 3 1 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat Sdh_cyt PF01127.22 AJA92268.1 - 6.9e-08 32.6 2.3 9.3e-08 32.1 1.8 1.4 1 1 1 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ferric_reduct PF01794.19 AJA92268.1 - 0.0047 17.0 1.4 0.0052 16.9 1.4 1.3 1 1 0 1 1 1 1 Ferric reductase like transmembrane component DUF4134 PF13572.6 AJA92269.1 - 0.013 15.7 5.9 0.1 12.9 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4134) Colicin_V PF02674.16 AJA92269.1 - 0.7 9.9 8.3 0.12 12.4 1.7 2.1 2 0 0 2 2 2 0 Colicin V production protein Rhodanese PF00581.20 AJA92270.1 - 6.1e-38 129.6 0.1 2.4e-19 69.8 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain DUF3562 PF12085.8 AJA92270.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) Peptidase_M50 PF02163.22 AJA92272.1 - 4.4e-20 72.0 0.6 1.1e-18 67.4 0.6 2.3 1 1 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 AJA92272.1 - 1.2e-12 48.0 0.2 2e-12 47.3 0.2 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 AJA92272.1 - 7e-07 29.0 1.3 1.2e-06 28.2 1.3 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AJA92272.1 - 2.7e-06 27.6 0.5 6e-06 26.5 0.5 1.6 2 0 0 2 2 2 1 PDZ domain Ammonium_transp PF00909.21 AJA92273.1 - 5.8e-107 357.8 32.0 1.1e-106 357.0 32.0 1.4 1 1 0 1 1 1 1 Ammonium Transporter Family Ribosomal_L11_N PF03946.14 AJA92274.1 - 1.5e-23 82.4 0.5 3.3e-23 81.3 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AJA92274.1 - 2.1e-15 57.0 1.6 3.2e-15 56.4 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF2777 PF10949.8 AJA92275.1 - 0.049 13.3 0.2 0.053 13.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) DEAD PF00270.29 AJA92276.1 - 3.5e-23 82.3 0.2 1.2e-22 80.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AJA92276.1 - 3.1e-13 50.1 0.1 3.1e-13 50.1 0.1 2.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AJA92276.1 - 2e-08 34.5 1.8 7.9e-07 29.4 0.1 3.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain HHH_2 PF12826.7 AJA92276.1 - 1.8e-06 28.0 0.1 1.1e-05 25.4 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AJA92276.1 - 0.00055 20.5 0.7 0.0015 19.1 0.7 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain T2SSE PF00437.20 AJA92276.1 - 0.019 14.1 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DNA_pol_lambd_f PF10391.9 AJA92276.1 - 0.18 11.7 2.2 2.2 8.2 0.0 3.2 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda PUA PF01472.20 AJA92277.1 - 5.9e-08 32.6 0.0 8.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 PUA domain TGT_C2 PF14810.6 AJA92277.1 - 1.5e-07 31.4 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Patch-forming domain C2 of tRNA-guanine transglycosylase Zn-C2H2_12 PF18112.1 AJA92278.1 - 0.013 15.9 0.1 0.022 15.2 0.1 1.4 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain GHMP_kinases_N PF00288.26 AJA92279.1 - 5.7e-14 52.1 1.4 1.2e-13 51.0 1.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AJA92279.1 - 3.6e-11 43.3 0.0 9.1e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal DUF2674 PF10879.8 AJA92279.1 - 0.072 12.7 0.6 1.1 8.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2674) TatC PF00902.18 AJA92280.1 - 2.3e-49 168.1 16.3 2.7e-49 167.8 16.3 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) Radical_SAM PF04055.21 AJA92281.1 - 3.1e-19 69.9 0.7 4.8e-18 66.1 0.6 2.2 2 0 0 2 2 2 1 Radical SAM superfamily BATS PF06968.13 AJA92281.1 - 8.4e-12 45.1 0.0 2.4e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain FAD_binding_7 PF03441.14 AJA92283.1 - 1.4e-76 256.5 1.5 2.1e-76 255.9 1.5 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 AJA92283.1 - 2.4e-31 108.9 0.1 4.5e-31 108.1 0.0 1.4 2 0 0 2 2 2 1 DNA photolyase ECR1_N PF14382.6 AJA92284.1 - 7.9e-07 28.8 0.0 1.9e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region DUF5331 PF17265.2 AJA92284.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5331) DNA_RNApol_7kD PF03604.13 AJA92284.1 - 1.2 8.9 6.0 6.1 6.6 5.9 2.2 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit AAA_17 PF13207.6 AJA92285.1 - 1.1e-30 106.8 0.0 1.4e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AJA92285.1 - 8.3e-07 29.6 0.0 1.6e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AJA92285.1 - 1.5e-05 25.3 0.0 2.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 AJA92285.1 - 2.9e-05 23.8 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain NACHT PF05729.12 AJA92285.1 - 0.00031 20.7 0.0 0.00033 20.6 0.0 1.4 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 AJA92285.1 - 0.00046 20.5 0.0 0.00066 20.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 AJA92285.1 - 0.00054 20.2 0.0 0.00096 19.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 AJA92285.1 - 0.00087 19.4 0.3 0.0019 18.2 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase CLP1_P PF16575.5 AJA92285.1 - 0.0015 18.4 0.0 0.0038 17.1 0.0 1.6 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop KTI12 PF08433.10 AJA92285.1 - 0.0016 17.9 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA PF00004.29 AJA92285.1 - 0.0019 18.6 0.1 0.0048 17.3 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AJA92285.1 - 0.0025 18.2 0.0 0.0048 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AJA92285.1 - 0.0028 17.8 0.0 0.0045 17.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AJA92285.1 - 0.0028 17.4 1.0 0.045 13.5 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 AJA92285.1 - 0.0029 18.0 0.2 0.0074 16.6 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AJA92285.1 - 0.0035 17.3 0.0 0.006 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 AJA92285.1 - 0.0039 16.6 0.2 0.0087 15.4 0.1 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Ras PF00071.22 AJA92285.1 - 0.0065 16.1 1.2 0.036 13.7 0.2 2.2 1 1 1 2 2 2 1 Ras family AAA_30 PF13604.6 AJA92285.1 - 0.0068 16.1 0.1 0.013 15.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AJA92285.1 - 0.0097 16.4 0.1 0.014 15.9 0.1 1.5 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 AJA92285.1 - 0.01 15.0 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 AJA92285.1 - 0.017 15.0 1.3 0.029 14.3 0.2 1.9 2 1 0 2 2 1 0 NTPase cobW PF02492.19 AJA92285.1 - 0.024 14.2 0.8 0.037 13.6 0.2 1.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 AJA92285.1 - 0.032 14.0 0.2 0.089 12.6 0.1 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 AJA92285.1 - 0.034 13.6 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Mg_chelatase PF01078.21 AJA92285.1 - 0.038 13.4 0.0 0.076 12.4 0.0 1.5 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI 6PF2K PF01591.18 AJA92285.1 - 0.05 12.9 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase RsgA_GTPase PF03193.16 AJA92285.1 - 0.053 13.4 0.2 0.1 12.5 0.2 1.7 1 1 0 1 1 1 0 RsgA GTPase MobB PF03205.14 AJA92285.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 AJA92285.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 AJA92285.1 - 0.075 11.9 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RuvB_N PF05496.12 AJA92285.1 - 0.075 12.8 0.2 0.63 9.8 0.0 2.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 AJA92285.1 - 0.099 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 AJA92285.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain HTH_34 PF13601.6 AJA92286.1 - 0.0065 16.6 0.1 0.0099 16.0 0.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_45 PF14947.6 AJA92286.1 - 0.039 13.9 0.1 0.057 13.4 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix AphA_like PF14557.6 AJA92286.1 - 0.057 13.1 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator TrmB PF01978.19 AJA92286.1 - 0.12 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Cyclin PF08613.11 AJA92286.1 - 0.18 12.2 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 Cyclin ATP-synt_F PF01990.17 AJA92287.1 - 4.5e-13 49.3 0.0 5.2e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit LUD_dom PF02589.15 AJA92287.1 - 0.021 14.5 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 LUD domain KH_1 PF00013.29 AJA92288.1 - 3.8e-07 29.8 0.7 1e-06 28.4 0.2 2.0 2 0 0 2 2 2 1 KH domain KH_6 PF15985.5 AJA92288.1 - 0.0018 18.6 0.0 0.0035 17.7 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 AJA92288.1 - 0.0051 16.6 0.2 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 AJA92288.1 - 0.076 12.9 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 KH domain APS_kinase PF01583.20 AJA92289.1 - 3.6e-49 166.7 0.0 4.2e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 AJA92289.1 - 2.2e-06 27.9 0.0 4.4e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AJA92289.1 - 0.00014 22.3 0.0 0.00019 21.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AJA92289.1 - 0.00019 22.0 0.0 0.00031 21.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 AJA92289.1 - 0.0014 18.2 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 AJA92289.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 AJA92289.1 - 0.0018 18.5 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AJA92289.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NTPase DSPc PF00782.20 AJA92290.1 - 4.9e-19 68.5 0.0 5.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AJA92290.1 - 1.2e-10 41.3 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 AJA92290.1 - 2.5e-06 27.6 0.4 0.00068 19.7 0.0 2.8 1 1 1 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 AJA92290.1 - 1.4e-05 25.3 0.0 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 AJA92290.1 - 0.00026 20.6 0.0 0.00037 20.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 AJA92290.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) zf-C2H2_2 PF12756.7 AJA92290.1 - 0.069 13.5 0.6 0.13 12.6 0.6 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DSPn PF14671.6 AJA92290.1 - 0.11 12.9 0.1 0.15 12.5 0.1 1.3 1 1 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half ChuX_HutX PF06228.13 AJA92291.1 - 3e-07 30.3 0.1 3.6e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX HemS PF05171.12 AJA92291.1 - 5.1e-06 26.4 0.1 5.8e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Haemin-degrading HemS.ChuX domain Na_H_Exchanger PF00999.21 AJA92292.1 - 3.8e-36 124.7 52.8 5.1e-36 124.3 52.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Iso_dh PF00180.20 AJA92293.1 - 1.3e-100 337.0 0.2 1.4e-100 336.8 0.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 AJA92293.1 - 0.0032 16.9 0.1 0.0084 15.6 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal phosphate biosynthetic protein PdxA CDC37_M PF08565.11 AJA92293.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain DUF166 PF02593.14 AJA92293.1 - 0.62 9.6 2.9 3.1 7.3 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function Hemerythrin PF01814.23 AJA92294.1 - 7e-12 46.1 5.7 9.3e-11 42.5 2.5 2.5 1 1 1 2 2 2 1 Hemerythrin HHE cation binding domain RIG-I_C PF18119.1 AJA92294.1 - 0.0013 18.7 0.9 0.0031 17.5 0.3 1.9 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain DUF2972 PF11186.8 AJA92294.1 - 0.41 10.5 4.5 2.3 8.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) Trp_halogenase PF04820.14 AJA92295.1 - 3.8e-05 22.7 0.0 0.00016 20.7 0.0 1.8 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_2 PF03446.15 AJA92295.1 - 0.0018 18.5 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Toprim_Crpt PF13342.6 AJA92295.1 - 0.0078 16.2 0.1 0.35 10.9 0.0 2.4 2 0 0 2 2 2 1 C-terminal repeat of topoisomerase ApbA PF02558.16 AJA92295.1 - 0.043 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 AJA92295.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 AJA92295.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HTH_24 PF13412.6 AJA92297.1 - 1.5e-11 43.7 1.0 1.5e-06 27.6 0.1 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AJA92297.1 - 3.5e-06 26.8 0.1 0.095 12.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AJA92297.1 - 1.3e-05 24.9 0.0 0.0056 16.5 0.0 2.1 2 0 0 2 2 2 2 MarR family MarR PF01047.22 AJA92297.1 - 0.00019 21.3 0.1 0.0066 16.4 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_34 PF13601.6 AJA92297.1 - 0.00092 19.3 0.1 1.4 9.1 0.0 2.2 2 0 0 2 2 2 2 Winged helix DNA-binding domain TrmB PF01978.19 AJA92297.1 - 0.012 15.5 2.5 1.1 9.1 0.2 2.5 1 1 2 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 AJA92297.1 - 0.05 13.7 0.0 7.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 AJA92297.1 - 0.26 11.2 1.6 2.9 7.9 0.1 2.2 2 0 0 2 2 2 0 HTH domain Nsp1_C PF05064.13 AJA92300.1 - 0.0014 18.4 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF2854 PF11016.8 AJA92300.1 - 0.082 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) DMRL_synthase PF00885.19 AJA92301.1 - 4.6e-33 114.0 0.8 5.2e-33 113.8 0.8 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Metallophos_3 PF14582.6 AJA92301.1 - 0.0048 16.3 0.1 0.0091 15.3 0.1 1.5 1 1 1 2 2 2 1 Metallophosphoesterase, calcineurin superfamily EVE PF01878.18 AJA92302.1 - 2.5e-37 128.1 0.1 2.8e-37 128.0 0.1 1.0 1 0 0 1 1 1 1 EVE domain SWIB PF02201.18 AJA92302.1 - 0.073 13.0 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 SWIB/MDM2 domain vATP-synt_E PF01991.18 AJA92303.1 - 4.2e-22 78.5 10.9 1.1e-21 77.2 9.8 2.1 1 1 1 2 2 2 1 ATP synthase (E/31 kDa) subunit DivIVA PF05103.13 AJA92303.1 - 0.018 15.1 9.3 0.42 10.7 6.4 2.2 1 1 1 2 2 2 0 DivIVA protein NBD_C PF17042.5 AJA92303.1 - 0.042 14.3 2.1 0.45 11.0 0.1 2.1 1 1 1 2 2 2 0 Nucleotide-binding C-terminal domain HD_2 PF12917.7 AJA92303.1 - 0.062 13.1 2.5 0.092 12.5 2.5 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme KAsynt_C_assoc PF16197.5 AJA92303.1 - 0.07 13.6 1.4 0.12 12.8 0.5 1.8 1 1 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension LXG PF04740.12 AJA92303.1 - 0.13 12.0 8.3 0.073 12.8 6.4 1.5 1 1 1 2 2 2 0 LXG domain of WXG superfamily DHR10 PF18595.1 AJA92303.1 - 0.23 11.5 7.2 0.35 10.9 7.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF3450 PF11932.8 AJA92303.1 - 0.52 9.6 6.5 0.58 9.4 5.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) HGTP_anticodon PF03129.20 AJA92304.1 - 2.1e-16 59.9 0.3 6.4e-16 58.3 0.2 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AJA92304.1 - 3.4e-12 46.7 0.3 5.1e-11 42.9 0.2 2.6 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) zf-RRPl_C4 PF17026.5 AJA92304.1 - 0.012 15.7 0.7 0.1 12.7 0.1 2.6 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 AJA92304.1 - 0.094 12.8 0.2 22 5.3 0.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 AJA92304.1 - 0.11 13.2 0.8 0.38 11.5 0.6 2.0 1 1 0 1 1 1 0 zinc-ribbon family A2L_zn_ribbon PF08792.10 AJA92304.1 - 0.26 11.1 1.7 7.1 6.5 0.3 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain YokU PF14122.6 AJA92304.1 - 0.29 11.2 2.0 0.46 10.5 0.0 2.3 2 1 1 3 3 3 0 YokU-like protein, putative antitoxin zf-C2H2_4 PF13894.6 AJA92304.1 - 1.4 9.9 4.1 1.3e+02 3.8 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger NMT1_2 PF13379.6 AJA92305.1 - 2.6e-29 102.7 0.0 3.6e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AJA92305.1 - 5.4e-15 55.9 0.0 7.9e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AJA92305.1 - 7.8e-08 32.2 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AJA92305.1 - 0.0016 17.9 0.0 0.45 9.9 0.0 2.2 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 AJA92305.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family LigT_PEase PF02834.16 AJA92306.1 - 1.3e-24 86.2 0.0 9e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.9 AJA92306.1 - 1.3e-12 48.0 1.1 3.2e-12 46.8 1.1 1.6 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 AJA92306.1 - 5.3e-10 39.4 0.0 6.6e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily dCMP_cyt_deam_1 PF00383.23 AJA92307.1 - 2.3e-27 94.8 0.8 2.9e-27 94.5 0.8 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AJA92307.1 - 2e-13 50.3 0.1 2.7e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase TRM PF02005.16 AJA92309.1 - 2.1e-79 267.4 0.0 2.5e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase FYVE PF01363.21 AJA92309.1 - 0.0047 17.0 0.5 0.0089 16.1 0.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger HypA PF01155.19 AJA92309.1 - 0.077 13.0 0.7 0.22 11.6 0.7 1.7 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 AJA92309.1 - 0.081 13.0 0.7 0.17 11.9 0.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon RNA_POL_M_15KD PF02150.16 AJA92309.1 - 0.28 11.1 2.9 0.85 9.6 2.9 1.9 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit Translin PF01997.16 AJA92311.1 - 6.1e-09 36.2 1.3 2.5e-07 30.9 1.3 2.2 1 1 0 1 1 1 1 Translin family AsnC_trans_reg PF01037.21 AJA92312.1 - 1.7e-09 37.5 0.2 1.8e-09 37.4 0.2 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GYD PF08734.11 AJA92312.1 - 0.0053 16.7 0.1 0.0058 16.6 0.1 1.1 1 0 0 1 1 1 1 GYD domain DUF5615 PF18480.1 AJA92313.1 - 8.1e-08 31.9 0.1 1.4e-07 31.2 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5615) Mut7-C PF01927.16 AJA92313.1 - 0.00029 21.0 0.0 0.00029 21.0 0.0 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain AsnC_trans_reg PF01037.21 AJA92314.1 - 1.9e-11 43.8 0.0 2.2e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 AJA92314.1 - 0.00067 19.7 0.1 0.00079 19.4 0.1 1.1 1 0 0 1 1 1 1 NapD protein IlvN PF07991.12 AJA92315.1 - 6.3e-67 224.3 0.3 8.6e-67 223.8 0.3 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 AJA92315.1 - 9.5e-55 184.8 1.0 1.5e-54 184.2 1.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 AJA92315.1 - 1e-07 31.5 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AJA92315.1 - 9.6e-07 29.1 0.2 6.6e-06 26.4 0.1 2.2 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AJA92315.1 - 0.0004 20.9 0.1 0.00091 19.8 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 AJA92315.1 - 0.003 17.7 0.1 0.0063 16.6 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HTH_AsnC-type PF13404.6 AJA92316.1 - 4e-14 52.1 0.1 8.5e-14 51.1 0.1 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 AJA92316.1 - 2.7e-13 49.7 0.3 4.3e-13 49.0 0.3 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AJA92316.1 - 1.4e-12 46.9 1.9 1.8e-12 46.6 0.5 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AJA92316.1 - 0.00066 19.5 0.1 0.0016 18.3 0.0 1.6 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 AJA92316.1 - 0.00077 19.4 0.2 0.0018 18.2 0.2 1.6 1 0 0 1 1 1 1 HTH domain Sigma70_r4 PF04545.16 AJA92316.1 - 0.0008 18.9 0.0 0.002 17.6 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 NapD PF03927.13 AJA92316.1 - 0.001 19.1 0.4 0.002 18.1 0.4 1.6 1 1 0 1 1 1 1 NapD protein Mga PF05043.13 AJA92316.1 - 0.0034 18.0 0.5 0.012 16.2 0.1 1.9 2 0 0 2 2 2 1 Mga helix-turn-helix domain HTH_IclR PF09339.10 AJA92316.1 - 0.006 16.4 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 AJA92316.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_DeoR PF08220.12 AJA92316.1 - 0.011 15.4 0.4 0.025 14.3 0.1 1.7 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain ACT_4 PF13291.6 AJA92316.1 - 0.016 15.7 0.7 0.28 11.8 0.2 2.2 1 1 1 2 2 2 0 ACT domain HTH_Mga PF08280.11 AJA92316.1 - 0.033 14.2 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_Tnp_ISL3 PF13542.6 AJA92316.1 - 0.035 13.5 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 GYD PF08734.11 AJA92316.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.7 1 1 1 2 2 2 0 GYD domain HTH_20 PF12840.7 AJA92316.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HHH PF00633.23 AJA92316.1 - 0.065 13.1 0.1 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif MarR PF01047.22 AJA92316.1 - 0.069 13.1 1.2 0.098 12.6 0.1 1.8 2 0 0 2 2 2 0 MarR family HECT_2 PF09814.9 AJA92316.1 - 0.076 11.9 0.1 0.079 11.8 0.1 1.0 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding polyprenyl_synt PF00348.17 AJA92317.1 - 3.3e-46 157.4 0.0 4.4e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Hydrolase_3 PF08282.12 AJA92318.1 - 5.8e-32 111.4 2.0 6.6e-20 71.9 0.2 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AJA92318.1 - 4.1e-09 36.3 0.0 0.00012 21.7 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AJA92318.1 - 1.6e-05 25.3 0.7 0.0024 18.2 0.0 2.6 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AJA92318.1 - 0.00017 22.0 0.8 0.0095 16.3 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 AJA92318.1 - 0.0029 16.8 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_6 PF13344.6 AJA92318.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribosomal_S13_N PF08069.12 AJA92319.1 - 2.1e-25 88.5 0.2 4e-25 87.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 AJA92319.1 - 2.3e-09 37.3 0.9 3.7e-09 36.7 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 COMMD1_N PF17221.3 AJA92319.1 - 0.0067 16.7 0.1 1.1 9.6 0.1 2.1 2 0 0 2 2 2 2 COMMD1 N-terminal domain HhH-GPD PF00730.25 AJA92320.1 - 1.8e-18 67.0 0.0 3.7e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RIO1 PF01163.22 AJA92320.1 - 4e-07 29.8 0.1 8.4e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 AJA92320.1 - 6.9e-06 25.6 0.5 6.9e-06 25.6 0.5 1.8 2 0 0 2 2 2 1 Protein kinase domain Pox_H7 PF04787.12 AJA92320.1 - 0.019 15.5 0.9 0.8 10.2 0.1 2.8 2 0 0 2 2 2 0 Late protein H7 Choline_kinase PF01633.20 AJA92320.1 - 0.072 12.7 0.0 0.87 9.1 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase TMEM51 PF15345.6 AJA92321.1 - 0.00014 21.8 0.0 0.00016 21.6 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 Tetraspanin PF00335.20 AJA92321.1 - 0.029 14.1 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family ATP1G1_PLM_MAT8 PF02038.16 AJA92321.1 - 0.13 11.7 1.5 2.3 7.7 0.1 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Ribosomal_L44 PF00935.19 AJA92322.1 - 7.9e-24 83.9 8.8 7.9e-24 83.9 8.8 1.4 1 1 1 2 2 2 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.11 AJA92322.1 - 0.023 14.9 0.7 0.023 14.9 0.7 2.1 1 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-TFIIB PF13453.6 AJA92322.1 - 0.1 11.9 0.3 1.9 7.9 0.1 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger Ribosomal_S17e PF00833.18 AJA92323.1 - 1e-17 64.1 6.3 1.2e-17 64.0 6.2 1.2 1 1 0 1 1 1 1 Ribosomal S17 DUF4525 PF15027.6 AJA92323.1 - 0.097 12.4 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Mit_KHE1 PF10173.9 AJA92323.1 - 0.23 11.5 1.9 0.24 11.5 1.9 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Kin17_mid PF10357.9 AJA92323.1 - 2.7 7.9 9.2 1.6 8.7 0.1 2.6 1 1 2 3 3 3 0 Domain of Kin17 curved DNA-binding protein KH_2 PF07650.17 AJA92324.1 - 2.9e-18 65.5 6.4 2.7e-13 49.5 0.4 2.1 1 1 1 2 2 2 2 KH domain KH_4 PF13083.6 AJA92324.1 - 6e-11 42.1 2.1 0.00021 21.1 0.2 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 AJA92324.1 - 1.6e-09 37.7 0.9 1.6e-09 37.7 0.9 2.0 2 0 0 2 2 2 1 NusA-like KH domain KH_1 PF00013.29 AJA92324.1 - 0.00056 19.7 1.5 0.0042 16.9 0.4 2.3 2 0 0 2 2 2 1 KH domain Glyphos_transf PF04464.14 AJA92325.1 - 4.9e-09 35.6 1.1 1.8e-08 33.8 1.1 1.8 1 1 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase DUF1944 PF09175.10 AJA92325.1 - 0.0093 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1944) Ribosomal_L23 PF00276.20 AJA92326.1 - 1.5e-14 54.1 1.7 1.2e-13 51.3 1.7 1.9 1 1 0 1 1 1 1 Ribosomal protein L23 ALS2CR8 PF15299.6 AJA92326.1 - 0.14 12.1 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DUF2299 PF10061.9 AJA92328.1 - 2.6e-15 56.4 1.4 3.2e-15 56.1 1.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2299) zf-C4_Topoisom PF01396.19 AJA92329.1 - 9e-05 22.2 11.5 0.00052 19.7 2.3 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger OS-D PF03392.13 AJA92329.1 - 0.015 15.4 3.0 0.015 15.4 3.0 2.3 2 1 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D Ribosomal_S27e PF01667.17 AJA92329.1 - 0.082 12.6 0.6 0.082 12.6 0.6 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 DUF2614 PF11023.8 AJA92329.1 - 0.084 13.0 0.4 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Zinc-ribbon containing domain PADR1 PF08063.12 AJA92329.1 - 4.3 7.2 10.4 2.9 7.7 2.6 2.7 2 1 0 2 2 2 0 PADR1 (NUC008) domain Ribosomal_L37ae PF01780.19 AJA92330.1 - 8.1e-17 61.1 1.5 9e-17 60.9 1.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family TF_Zn_Ribbon PF08271.12 AJA92330.1 - 0.0014 18.1 1.2 0.0022 17.5 1.2 1.4 1 1 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 AJA92330.1 - 0.0015 17.9 1.9 0.21 11.0 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain C1_1 PF00130.22 AJA92330.1 - 0.0036 17.1 1.0 0.005 16.7 1.0 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.11 AJA92330.1 - 0.0097 15.8 1.0 0.017 15.0 1.0 1.7 1 1 0 1 1 1 1 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.10 AJA92330.1 - 0.011 15.5 0.2 0.017 14.8 0.2 1.3 1 0 0 1 1 1 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 AJA92330.1 - 0.012 15.5 2.0 0.012 15.5 2.0 1.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.7 AJA92330.1 - 0.013 15.5 0.9 0.026 14.6 0.8 1.4 1 1 0 1 1 1 0 Double zinc ribbon DNA_ligase_ZBD PF03119.16 AJA92330.1 - 0.013 15.5 2.9 0.019 14.9 2.9 1.4 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain ADK_lid PF05191.14 AJA92330.1 - 0.018 15.0 2.2 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_3 PF13878.6 AJA92330.1 - 0.023 14.5 0.5 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Zn-ribbon_8 PF09723.10 AJA92330.1 - 0.027 14.6 4.8 0.035 14.2 0.4 2.1 1 1 1 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 AJA92330.1 - 0.043 14.0 1.1 0.067 13.4 1.1 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rep_fac-A_C PF08646.10 AJA92330.1 - 0.079 12.7 0.4 0.081 12.7 0.4 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf_UBZ PF18439.1 AJA92330.1 - 0.098 12.3 0.4 9.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-tcix PF14952.6 AJA92330.1 - 0.1 12.2 5.5 0.99 9.1 0.9 2.4 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding YhfH PF14149.6 AJA92330.1 - 0.14 12.2 2.3 3.4 7.7 0.2 2.2 2 0 0 2 2 2 0 YhfH-like protein zf-C4_Topoisom PF01396.19 AJA92330.1 - 0.14 12.0 0.6 0.14 12.0 0.6 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_2 PF13240.6 AJA92330.1 - 0.26 11.1 4.4 5.4 6.9 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.6 AJA92330.1 - 0.78 9.9 3.4 1.6 8.9 0.4 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-IS66 PF13005.7 AJA92330.1 - 2.5 8.6 8.1 3.7 8.0 1.5 2.2 1 1 2 3 3 3 0 zinc-finger binding domain of transposase IS66 tRNA-synt_2c PF01411.19 AJA92332.1 - 1.6e-83 281.1 0.0 1.6e-83 281.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 AJA92332.1 - 1.2e-15 57.3 1.2 1.2e-15 57.3 1.2 2.2 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 AJA92332.1 - 1.7e-05 25.2 12.0 0.00039 20.8 12.0 2.6 1 1 0 1 1 1 1 DHHA1 domain tRNA-synt_2e PF02091.15 AJA92332.1 - 0.0052 16.1 0.7 0.01 15.1 0.1 1.7 2 0 0 2 2 2 1 Glycyl-tRNA synthetase alpha subunit CAF1 PF04857.20 AJA92332.1 - 1.6 7.8 5.3 7.5 5.6 5.2 1.8 1 1 0 1 1 1 0 CAF1 family ribonuclease UbiA PF01040.18 AJA92333.1 - 2.2e-29 102.5 16.5 3e-29 102.1 16.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3488 PF11992.8 AJA92333.1 - 0.76 8.7 8.2 0.029 13.3 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) Aconitase_C PF00694.19 AJA92335.1 - 8.9e-23 81.1 0.1 4.6e-22 78.7 0.0 2.1 2 1 0 2 2 2 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 AJA92335.1 - 0.0073 16.0 0.3 0.035 13.7 0.3 2.0 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus TrmB PF01978.19 AJA92336.1 - 4e-05 23.4 0.1 5.1e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 AJA92336.1 - 0.00019 21.3 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 HTH domain Fe_dep_repress PF01325.19 AJA92336.1 - 0.0017 18.5 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain FUR PF01475.19 AJA92336.1 - 0.0053 16.9 0.0 0.0069 16.5 0.0 1.3 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_20 PF12840.7 AJA92336.1 - 0.0054 16.8 0.0 0.0069 16.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AJA92336.1 - 0.014 15.3 0.1 0.022 14.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_7 PF02796.15 AJA92336.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Smg4_UPF3 PF03467.15 AJA92336.1 - 0.017 15.1 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Smg-4/UPF3 family HTH_30 PF13556.6 AJA92336.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.5 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AJA92336.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 MarR family TFIIE_alpha PF02002.17 AJA92336.1 - 0.027 14.3 0.1 0.033 14.1 0.1 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit PadR PF03551.14 AJA92336.1 - 0.039 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_23 PF13384.6 AJA92336.1 - 0.039 13.7 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AJA92336.1 - 0.053 13.2 0.1 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_34 PF13601.6 AJA92336.1 - 0.054 13.7 0.1 0.067 13.4 0.1 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain UPF0122 PF04297.14 AJA92336.1 - 0.057 13.7 0.3 0.13 12.5 0.3 1.7 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like DUF2250 PF10007.9 AJA92336.1 - 0.066 13.3 0.1 0.076 13.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_24 PF13412.6 AJA92336.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AJA92336.1 - 0.15 11.8 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain Oxidored_q6 PF01058.22 AJA92337.1 - 1.8e-24 86.0 0.1 2.5e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF309 PF03745.14 AJA92338.1 - 4.6e-19 67.9 0.2 8.7e-19 67.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF309) DUF4455 PF14643.6 AJA92338.1 - 0.0087 14.8 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) Calpain_inhib PF00748.19 AJA92338.1 - 0.066 13.7 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 Calpain inhibitor Sh_2 PF17512.2 AJA92338.1 - 0.098 12.4 0.5 0.44 10.3 0.1 2.0 1 1 1 2 2 2 0 Metapneumovirus Small hydrophobic protein GCD14 PF08704.10 AJA92339.1 - 6e-34 117.8 0.0 8.4e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 AJA92339.1 - 1.6e-11 44.2 0.0 2.5e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AJA92339.1 - 3.9e-10 39.8 0.1 5.5e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 AJA92339.1 - 2.5e-09 36.8 0.0 5.3e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AJA92339.1 - 1.1e-07 32.5 0.0 2.5e-07 31.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 AJA92339.1 - 1.1e-07 32.8 0.0 2.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJA92339.1 - 1.2e-05 25.9 0.0 2.5e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 AJA92339.1 - 0.00013 21.8 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 AJA92339.1 - 0.00015 22.5 0.0 0.00045 20.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 AJA92339.1 - 0.00015 21.5 0.1 0.00042 20.1 0.0 1.8 2 0 0 2 2 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_3 PF01596.17 AJA92339.1 - 0.00015 21.0 0.1 0.00022 20.5 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.7 AJA92339.1 - 0.00016 21.7 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AJA92339.1 - 0.00019 21.0 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 AJA92339.1 - 0.00022 21.2 0.0 0.00041 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AJA92339.1 - 0.00034 20.2 0.0 0.001 18.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 AJA92339.1 - 0.00055 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 AJA92339.1 - 0.0042 16.2 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.17 AJA92339.1 - 0.0073 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Met_10 PF02475.16 AJA92339.1 - 0.024 14.4 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.19 AJA92339.1 - 0.066 13.3 0.0 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PfkB PF00294.24 AJA92340.1 - 1.7e-24 86.6 0.3 2.9e-24 85.9 0.3 1.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AJA92340.1 - 0.0005 19.5 0.2 0.00097 18.6 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Ribosomal_S28e PF01200.18 AJA92343.1 - 3.1e-25 87.9 3.9 3.5e-25 87.7 3.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Peptidase_M1 PF01433.20 AJA92344.1 - 8.1e-90 300.2 1.6 8.1e-90 300.2 1.6 2.5 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 AJA92344.1 - 3.6e-60 204.2 3.0 4.6e-59 200.5 2.0 2.3 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 AJA92344.1 - 1.7e-49 168.6 3.0 2.5e-49 168.0 1.3 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 AJA92344.1 - 0.0028 17.1 2.8 0.0038 16.7 0.1 2.2 2 0 0 2 2 2 1 Putative aminopeptidase Med31 PF05669.12 AJA92344.1 - 3.6 7.7 8.6 0.6 10.1 3.0 2.6 2 1 1 3 3 3 0 SOH1 zinc_ribbon_2 PF13240.6 AJA92345.1 - 5.7e-08 32.2 5.0 8.7e-08 31.6 5.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AJA92345.1 - 7.3e-05 22.7 0.9 0.0001 22.2 0.9 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 AJA92345.1 - 0.00015 21.0 4.0 0.00027 20.2 4.0 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 AJA92345.1 - 0.0077 17.0 0.1 0.011 16.5 0.1 1.3 1 0 0 1 1 1 1 zinc-ribbon family DUF1610 PF07754.11 AJA92345.1 - 0.089 12.8 1.7 0.27 11.2 1.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1610) DUF35_N PF12172.8 AJA92345.1 - 0.28 11.1 2.1 0.51 10.3 2.1 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) YhfH PF14149.6 AJA92345.1 - 2.2 8.3 7.9 15 5.7 1.0 3.0 2 1 1 3 3 3 0 YhfH-like protein zf-dskA_traR PF01258.17 AJA92345.1 - 3.5 7.6 5.1 24 4.9 5.1 2.2 1 1 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger Nudix_N_2 PF14803.6 AJA92345.1 - 7.9 6.5 7.5 6.2 6.8 1.8 2.2 2 0 0 2 2 2 0 Nudix N-terminal Peptidase_M17 PF00883.21 AJA92346.1 - 1.1e-118 396.1 0.1 1.4e-118 395.7 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 AJA92346.1 - 1.2e-19 70.4 0.2 3.3e-19 69.0 0.2 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain RE_NgoFVII PF09565.10 AJA92346.1 - 0.12 11.7 3.2 0.14 11.4 0.7 2.0 1 1 0 2 2 2 0 NgoFVII restriction endonuclease SnoaL_3 PF13474.6 AJA92347.1 - 5.6e-05 23.4 0.0 7.2e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 AJA92347.1 - 0.0008 19.6 0.1 0.0018 18.4 0.1 1.7 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain AMMECR1 PF01871.17 AJA92347.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 AMMECR1 DUF4440 PF14534.6 AJA92347.1 - 0.02 15.3 0.0 0.023 15.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) LDcluster4 PF18306.1 AJA92348.1 - 5.8e-46 155.9 0.6 6.6e-46 155.8 0.6 1.0 1 0 0 1 1 1 1 SLOG cluster4 family Lysine_decarbox PF03641.14 AJA92348.1 - 0.00052 20.1 0.0 0.0013 18.8 0.0 1.7 1 1 0 1 1 1 1 Possible lysine decarboxylase LSDAT_prok PF18171.1 AJA92348.1 - 0.0041 16.4 0.1 0.012 14.9 0.0 1.7 2 0 0 2 2 2 1 SLOG in TRPM, prokaryote DNA_processg_A PF02481.15 AJA92348.1 - 0.0042 16.4 0.2 0.12 11.6 0.1 2.1 2 0 0 2 2 2 1 DNA recombination-mediator protein A DAGK_cat PF00781.24 AJA92348.1 - 0.1 12.2 3.6 0.34 10.5 0.1 2.4 1 1 1 2 2 2 0 Diacylglycerol kinase catalytic domain Sod_Fe_C PF02777.18 AJA92349.1 - 9.9e-39 131.6 0.1 1.6e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AJA92349.1 - 2.5e-29 101.6 1.0 3.9e-29 100.9 1.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DNA_gyraseB PF00204.25 AJA92349.1 - 0.0088 15.5 0.1 0.017 14.6 0.0 1.5 2 0 0 2 2 2 1 DNA gyrase B Ribosomal_L15e PF00827.17 AJA92350.1 - 1.3e-43 148.9 4.9 1.6e-43 148.6 4.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 KorB_C PF06613.11 AJA92350.1 - 0.09 12.8 0.6 4.6 7.3 0.0 2.3 1 1 1 2 2 2 0 KorB C-terminal beta-barrel domain Ribo_biogen_C PF04034.13 AJA92351.1 - 3.1e-35 120.7 0.0 4.2e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 AJA92351.1 - 9e-07 28.6 0.1 1.7e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Nif11 PF07862.11 AJA92351.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Nif11 domain Lyase_1 PF00206.20 AJA92352.1 - 1.8e-50 172.1 0.0 3.5e-50 171.2 0.0 1.5 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 AJA92352.1 - 2.2e-13 50.8 0.1 1.3e-12 48.3 0.0 2.3 2 1 0 2 2 2 1 Argininosuccinate lyase C-terminal FlaC_arch PF05377.11 AJA92352.1 - 0.32 11.4 2.7 3.4 8.1 0.4 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Aconitase PF00330.20 AJA92353.1 - 7.2e-93 312.1 3.5 9e-91 305.2 3.5 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) FBPase_3 PF01950.16 AJA92354.1 - 1e-147 492.1 0.1 1.2e-147 491.9 0.1 1.0 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase Ribosomal_L6 PF00347.23 AJA92355.1 - 3.3e-13 50.1 6.9 2.3e-07 31.4 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 FMN_red PF03358.15 AJA92356.1 - 1.3e-25 90.0 0.0 1.5e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AJA92356.1 - 5.9e-11 42.5 0.0 8.1e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold PS_pyruv_trans PF04230.13 AJA92356.1 - 0.044 13.7 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase HTH_44 PF14641.6 AJA92356.1 - 0.19 12.2 1.2 0.7 10.4 0.2 2.0 1 1 1 2 2 2 0 Helix-turn-helix DNA-binding domain of SPT6 Pentapeptide PF00805.22 AJA92357.1 - 8.1e-127 412.0 121.3 8.2e-13 47.7 0.9 14.0 2 2 16 19 19 19 19 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AJA92357.1 - 1.6e-66 220.4 24.3 2.2e-12 47.0 2.7 9.1 2 2 7 9 9 9 9 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AJA92357.1 - 3.7e-48 161.4 16.6 4.7e-06 26.6 0.4 12.6 3 3 7 11 11 11 10 Pentapeptide repeats (9 copies) CfAFP PF05264.11 AJA92357.1 - 3.1e-05 24.0 9.7 0.86 9.6 0.0 5.4 1 1 5 7 7 7 3 Choristoneura fumiferana antifreeze protein (CfAFP) Methyltransf_11 PF08241.12 AJA92357.1 - 0.13 12.9 2.0 29 5.4 0.0 4.5 3 2 3 6 6 6 0 Methyltransferase domain Cue1_U7BR PF18499.1 AJA92357.1 - 1.7 8.7 5.6 2.3 8.3 1.1 3.6 3 1 0 3 3 3 0 Ubc7p-binding region of Cue1 Peptidase_A4 PF01828.17 AJA92357.1 - 5.1 6.5 9.5 6.8 6.1 0.8 3.6 2 1 1 3 3 3 0 Peptidase A4 family DZR PF12773.7 AJA92358.1 - 5.1e-06 26.4 6.7 0.00018 21.5 1.9 2.3 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 AJA92358.1 - 2.1e-05 25.2 2.7 0.014 16.1 0.4 2.2 2 0 0 2 2 2 2 zinc-ribbon family zinc_ribbon_2 PF13240.6 AJA92358.1 - 8.5e-05 22.1 5.2 0.00021 20.9 5.2 1.7 1 0 0 1 1 1 1 zinc-ribbon domain PRC PF05239.16 AJA92358.1 - 0.00032 20.7 1.5 0.0014 18.7 1.4 1.9 1 1 0 1 1 1 1 PRC-barrel domain zf-ribbon_3 PF13248.6 AJA92358.1 - 0.0055 16.1 3.7 0.0055 16.1 3.7 2.4 3 0 0 3 3 3 1 zinc-ribbon domain zf-RanBP PF00641.18 AJA92358.1 - 0.015 14.6 3.7 0.015 14.6 3.7 2.3 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zinc-ribbons_6 PF07191.12 AJA92358.1 - 0.017 15.1 6.7 1.4 9.0 0.3 2.8 2 1 0 2 2 2 0 zinc-ribbons DUF2199 PF09965.9 AJA92358.1 - 0.15 12.1 0.3 0.33 11.0 0.3 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) zf-CHY PF05495.12 AJA92358.1 - 0.15 12.5 3.5 1.7 9.2 0.2 2.3 2 0 0 2 2 2 0 CHY zinc finger Gin PF10764.9 AJA92358.1 - 1.6 8.8 5.8 32 4.6 0.0 3.2 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin zf-dskA_traR PF01258.17 AJA92358.1 - 3.8 7.5 7.9 3.4 7.7 0.2 3.1 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger AhpC-TSA PF00578.21 AJA92359.1 - 7e-32 110.0 0.1 8e-32 109.8 0.1 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJA92359.1 - 5.9e-21 74.7 0.1 7.1e-21 74.5 0.1 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 AJA92359.1 - 0.0096 15.8 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Fer4 PF00037.27 AJA92360.1 - 7.6e-12 44.5 10.8 3.2e-09 36.2 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AJA92360.1 - 1.2e-08 34.9 16.4 9.9e-05 22.4 0.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AJA92360.1 - 1.7e-08 34.9 6.5 2.8e-08 34.2 6.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJA92360.1 - 1.8e-07 31.2 20.5 5.5e-05 23.2 11.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AJA92360.1 - 8.7e-07 29.3 1.2 0.0038 17.7 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJA92360.1 - 9.7e-07 28.9 7.0 2.2e-06 27.7 7.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AJA92360.1 - 7.8e-06 26.7 2.4 0.0032 18.4 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AJA92360.1 - 1e-05 25.3 9.8 0.0016 18.4 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AJA92360.1 - 1.9e-05 24.5 11.8 4.3e-05 23.4 1.7 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_4 PF12800.7 AJA92360.1 - 8.9e-05 22.7 8.0 0.012 16.0 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AJA92360.1 - 0.0013 19.2 9.8 0.028 15.0 0.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_15 PF13459.6 AJA92360.1 - 0.0014 19.3 4.4 0.16 12.8 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.6 AJA92360.1 - 0.0019 18.7 4.0 0.11 13.0 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 AJA92360.1 - 0.011 16.6 4.1 0.011 16.6 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 AJA92360.1 - 0.025 15.4 5.3 0.27 12.1 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AJA92360.1 - 0.12 12.6 8.9 0.4 10.9 1.2 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Cytochrome_B PF00033.19 AJA92361.1 - 8e-28 97.5 11.9 8e-28 97.5 11.9 2.3 3 0 0 3 3 3 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 AJA92361.1 - 6.3e-25 88.1 7.2 6.3e-25 88.1 7.2 3.1 2 1 1 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 AJA92361.1 - 1.4e-09 38.2 2.7 1.4e-09 38.2 2.7 3.5 4 0 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD DUF4405 PF14358.6 AJA92361.1 - 0.00022 21.7 2.8 0.00022 21.7 2.8 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4405) TPR_1 PF00515.28 AJA92363.1 - 1.2e-11 43.9 3.6 3.5e-05 23.4 0.3 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 AJA92363.1 - 2e-09 36.9 1.3 0.00018 21.4 0.2 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AJA92363.1 - 9.1e-09 34.8 0.1 0.01 15.9 0.0 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AJA92363.1 - 0.0029 17.8 0.1 0.016 15.4 0.1 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 AJA92363.1 - 0.031 14.8 0.0 0.57 10.7 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 AJA92363.1 - 0.041 14.2 0.0 1.8 8.9 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat SOXp PF12336.8 AJA92363.1 - 0.083 14.0 0.0 0.12 13.4 0.0 1.3 1 0 0 1 1 1 0 SOX transcription factor Ribosomal_S30 PF04758.14 AJA92364.1 - 4.1e-11 42.9 3.6 5.5e-11 42.5 3.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 AA_permease_2 PF13520.6 AJA92365.1 - 2.4e-43 148.5 53.3 3.9e-43 147.9 53.3 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AJA92365.1 - 1.4e-35 122.8 46.4 1.9e-35 122.4 46.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 AJA92365.1 - 2.1e-07 30.9 4.4 2.1e-07 30.9 4.4 3.6 5 0 0 5 5 5 1 C-terminus of AA_permease Usp PF00582.26 AJA92365.1 - 7.6e-06 26.5 0.0 0.003 18.1 0.0 2.3 2 0 0 2 2 2 2 Universal stress protein family DUF2560 PF10834.8 AJA92365.1 - 0.16 12.2 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) Spore_permease PF03845.13 AJA92365.1 - 5.1 5.8 26.9 0.019 13.8 6.9 3.4 2 1 0 2 2 2 0 Spore germination protein FGE-sulfatase PF03781.16 AJA92366.1 - 2.3e-45 155.2 2.0 3.3e-45 154.7 2.0 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 AJA92366.1 - 6.7e-11 42.8 0.3 2.6e-10 40.9 0.3 2.0 1 1 0 1 1 1 1 DinB superfamily CTP_transf_like PF01467.26 AJA92367.1 - 1.3e-13 51.4 0.2 7.6e-12 45.6 0.2 2.1 1 1 1 2 2 2 2 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 AJA92367.1 - 0.047 13.4 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain HIGH_NTase1 PF05636.11 AJA92367.1 - 0.05 12.8 0.2 5.6 6.1 0.0 2.2 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase HIGH_NTase1_ass PF16581.5 AJA92367.1 - 0.055 13.5 0.1 0.95 9.4 0.0 2.1 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region Peptidase_M20 PF01546.28 AJA92368.1 - 1e-30 107.0 0.0 1.4e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AJA92368.1 - 1.2e-18 67.0 0.0 2.3e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Latexin PF06907.12 AJA92368.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Latexin WG_beta_rep PF14903.6 AJA92368.1 - 0.41 11.0 3.7 1.7 9.0 0.2 3.1 3 0 0 3 3 3 0 WG containing repeat Aminotran_4 PF01063.19 AJA92369.1 - 5.1e-52 176.9 0.0 6.2e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Lipoprotein_Ltp PF07553.11 AJA92369.1 - 3.4 8.0 5.0 0.37 11.1 0.3 1.8 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein Radical_SAM PF04055.21 AJA92370.1 - 2.9e-12 47.3 0.0 6.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 AJA92370.1 - 0.071 13.1 0.1 0.19 11.8 0.1 1.8 1 1 0 1 1 1 0 B12 binding domain Aminotran_1_2 PF00155.21 AJA92371.1 - 1.4e-59 202.1 0.0 1.7e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AJA92371.1 - 3.2e-07 30.0 0.0 5.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AJA92371.1 - 7.1e-06 25.2 0.0 1.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AJA92371.1 - 1.1e-05 24.2 0.0 1.6e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF4116 PF13475.6 AJA92371.1 - 0.0044 16.7 0.6 0.84 9.4 0.1 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4116) Beta_elim_lyase PF01212.21 AJA92371.1 - 0.16 11.2 0.0 0.57 9.4 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase DUF2304 PF10066.9 AJA92372.1 - 0.012 15.9 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) LapA_dom PF06305.11 AJA92372.1 - 0.02 14.7 0.3 0.03 14.2 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CcmD PF04995.14 AJA92372.1 - 0.021 14.9 0.2 0.031 14.3 0.2 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) UreD PF01774.17 AJA92373.1 - 3e-40 138.4 0.0 3.6e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Cdc6_C PF09079.11 AJA92374.1 - 3.9e-17 62.0 0.3 8.7e-17 60.9 0.3 1.6 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 AJA92374.1 - 1.6e-12 47.9 0.0 4.2e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AJA92374.1 - 3.7e-10 40.3 0.9 1.4e-09 38.5 0.1 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AJA92374.1 - 7.2e-10 39.5 0.0 3.1e-09 37.4 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain TniB PF05621.11 AJA92374.1 - 4.9e-06 26.1 0.0 1.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 AJA92374.1 - 5.2e-06 26.5 0.1 1.4e-05 25.1 0.0 1.7 2 0 0 2 2 1 1 NACHT domain ATPase_2 PF01637.18 AJA92374.1 - 2.7e-05 24.2 1.6 0.0001 22.3 0.3 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 AJA92374.1 - 3.6e-05 23.2 0.3 0.17 11.1 0.0 2.3 1 1 0 2 2 2 2 KAP family P-loop domain DUF2075 PF09848.9 AJA92374.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 AJA92374.1 - 0.0003 20.1 0.1 0.0011 18.2 0.0 1.9 3 0 0 3 3 3 1 PIF1-like helicase AAA_32 PF13654.6 AJA92374.1 - 0.0004 19.3 0.7 0.15 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 AJA92374.1 - 0.00083 18.9 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region NB-ARC PF00931.22 AJA92374.1 - 0.00098 18.4 0.4 0.0025 17.1 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_assoc_2 PF16193.5 AJA92374.1 - 0.00099 19.4 0.5 0.0027 18.0 0.5 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_19 PF13245.6 AJA92374.1 - 0.001 19.4 1.5 0.0031 17.8 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 AJA92374.1 - 0.0012 18.8 1.5 0.0092 16.0 0.4 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 AJA92374.1 - 0.0046 16.8 0.8 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 AJA92374.1 - 0.0048 16.8 2.6 0.073 13.0 2.7 2.5 1 1 1 2 2 2 1 NTPase DUF815 PF05673.13 AJA92374.1 - 0.0052 16.0 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Rad17 PF03215.15 AJA92374.1 - 0.0057 16.6 0.3 0.016 15.1 0.0 1.8 2 0 0 2 2 1 1 Rad17 P-loop domain AAA_lid_10 PF17872.1 AJA92374.1 - 0.01 15.9 0.2 0.03 14.5 0.2 1.9 1 0 0 1 1 1 0 AAA lid domain RNA_helicase PF00910.22 AJA92374.1 - 0.016 15.6 0.0 0.048 14.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 AJA92374.1 - 0.018 14.8 0.6 0.046 13.4 0.6 1.8 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 AJA92374.1 - 0.025 14.0 1.0 0.44 9.9 1.0 2.5 1 1 0 1 1 1 0 KaiC AAA_30 PF13604.6 AJA92374.1 - 0.027 14.2 0.0 0.074 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain Phage-MuB_C PF09077.11 AJA92374.1 - 0.034 14.0 1.0 0.091 12.6 0.4 2.0 2 0 0 2 2 2 0 Mu B transposition protein, C terminal TrwB_AAD_bind PF10412.9 AJA92374.1 - 0.038 12.9 0.1 0.097 11.6 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF359 PF04019.12 AJA92374.1 - 0.039 13.6 1.1 6.2 6.5 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF359) T2SSF PF00482.23 AJA92374.1 - 0.044 13.7 1.2 0.66 9.9 0.7 2.8 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F TsaE PF02367.17 AJA92374.1 - 0.054 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49_C PF17856.1 AJA92374.1 - 0.063 13.4 0.4 0.17 12.0 0.4 1.8 1 0 0 1 1 1 0 TIP49 AAA-lid domain Mg_chelatase PF01078.21 AJA92374.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_34 PF13872.6 AJA92374.1 - 0.11 11.3 0.2 0.53 9.1 0.1 2.0 2 1 1 3 3 3 0 P-loop containing NTP hydrolase pore-1 Complex1_30kDa PF00329.19 AJA92375.1 - 3.1e-32 111.8 0.0 4.1e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Rsa3 PF14615.6 AJA92375.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Ribosomal_L18 PF17135.4 AJA92377.1 - 7e-09 35.3 0.1 7.7e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 AJA92377.1 - 2e-06 28.5 3.4 4.4e-06 27.4 3.4 1.6 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HU-CCDC81_euk_1 PF14908.6 AJA92377.1 - 0.14 12.3 0.3 0.34 11.1 0.2 1.7 2 1 0 2 2 2 0 CCDC81 eukaryotic HU domain 1 Trypan_PARP PF05887.11 AJA92378.1 - 0.0027 17.7 3.1 0.0035 17.3 3.1 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TctB PF07331.11 AJA92378.1 - 0.0064 16.8 1.2 0.0096 16.2 1.2 1.2 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family DUF5379 PF17350.2 AJA92378.1 - 0.037 14.3 6.6 0.098 12.9 6.3 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5379) DUF4366 PF14283.6 AJA92378.1 - 0.04 14.0 1.7 0.068 13.2 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Rer1 PF03248.13 AJA92378.1 - 0.32 10.7 5.4 0.43 10.3 0.5 2.5 1 1 1 2 2 2 0 Rer1 family RseC_MucC PF04246.12 AJA92378.1 - 0.48 10.4 1.6 0.96 9.4 0.2 1.8 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Rib_recp_KP_reg PF05104.12 AJA92378.1 - 0.72 10.9 11.3 1 10.4 11.3 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region AIF-MLS PF14962.6 AJA92378.1 - 0.85 9.6 6.1 1.3 9.0 6.1 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence TIM PF00121.18 AJA92379.1 - 2.5e-10 40.1 3.2 9.3e-09 35.0 0.9 2.1 1 1 1 2 2 2 2 Triosephosphate isomerase IGPS PF00218.21 AJA92379.1 - 0.0011 18.1 0.1 0.0021 17.3 0.1 1.4 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase ThiG PF05690.14 AJA92379.1 - 0.0024 17.2 0.1 0.0057 16.0 0.1 1.6 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 AJA92379.1 - 0.0068 15.5 0.6 0.018 14.1 0.1 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DUF5081 PF16887.5 AJA92379.1 - 0.087 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) HTH_24 PF13412.6 AJA92380.1 - 6.4e-18 64.1 0.0 9.4e-11 41.1 0.1 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AJA92380.1 - 3.1e-10 39.8 0.0 3.4e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family MarR PF01047.22 AJA92380.1 - 3.2e-09 36.6 0.1 0.0009 19.1 0.0 2.2 2 0 0 2 2 2 2 MarR family TrmB PF01978.19 AJA92380.1 - 4.3e-09 36.1 0.3 1.6e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 AJA92380.1 - 1.3e-08 34.9 0.5 0.0015 18.7 0.0 2.2 2 0 0 2 2 2 2 Winged helix DNA-binding domain MarR_2 PF12802.7 AJA92380.1 - 5.6e-06 26.1 0.0 0.0037 17.1 0.0 2.3 2 0 0 2 2 2 2 MarR family HxlR PF01638.17 AJA92380.1 - 0.00021 21.1 0.1 0.017 14.9 0.1 2.2 1 1 1 2 2 2 1 HxlR-like helix-turn-helix HTH_45 PF14947.6 AJA92380.1 - 0.00029 20.8 0.3 0.11 12.5 0.0 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix HTH_IclR PF09339.10 AJA92380.1 - 0.00069 19.4 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain FaeA PF04703.12 AJA92380.1 - 0.0045 17.3 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 1 FaeA-like protein Rrf2 PF02082.20 AJA92380.1 - 0.0058 17.0 0.2 0.28 11.5 0.0 2.3 2 0 0 2 2 2 1 Transcriptional regulator HTH_27 PF13463.6 AJA92380.1 - 0.0083 16.6 0.0 0.1 13.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_20 PF12840.7 AJA92380.1 - 0.016 15.3 0.0 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain RPA_C PF08784.11 AJA92380.1 - 0.02 15.5 0.2 1.2 9.8 0.0 2.4 2 1 1 3 3 2 0 Replication protein A C terminal RNA_pol_Rpc34 PF05158.12 AJA92380.1 - 0.021 14.2 1.1 0.12 11.7 0.1 2.1 2 1 0 2 2 2 0 RNA polymerase Rpc34 subunit HTH_Crp_2 PF13545.6 AJA92380.1 - 0.026 14.5 0.1 9.2 6.3 0.0 2.6 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_40 PF14493.6 AJA92380.1 - 0.039 14.4 0.0 0.22 12.0 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain Penicillinase_R PF03965.16 AJA92380.1 - 0.047 14.1 1.1 1.7 9.0 0.1 2.5 1 1 1 2 2 2 0 Penicillinase repressor Fe_dep_repress PF01325.19 AJA92380.1 - 0.049 13.8 0.3 2 8.7 0.0 2.6 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain RP-C PF03428.13 AJA92380.1 - 0.082 12.6 0.0 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 Replication protein C N-terminal domain HTH_41 PF14502.6 AJA92380.1 - 0.16 11.7 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LPG_synthase_TM PF03706.13 AJA92381.1 - 2.2e-21 76.7 20.4 3.6e-21 76.0 20.4 1.3 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region DUF1218 PF06749.12 AJA92381.1 - 0.3 11.6 0.2 0.3 11.6 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) CcmD PF04995.14 AJA92381.1 - 9.3 6.4 10.5 2.2 8.4 0.3 2.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) CoA_binding PF02629.19 AJA92382.1 - 2.6e-22 79.3 3.0 3.9e-22 78.8 0.4 2.3 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 AJA92382.1 - 1.6e-09 37.7 0.2 2.9e-09 36.9 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 AJA92382.1 - 1.6e-06 27.9 0.1 2.6e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AJA92382.1 - 4.1e-05 24.1 0.0 6.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 AJA92382.1 - 0.00043 21.1 0.2 0.0012 19.7 0.1 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.12 AJA92382.1 - 0.00086 18.9 0.5 0.0016 18.0 0.5 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ribul_P_3_epim PF00834.19 AJA92382.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DapB_N PF01113.20 AJA92382.1 - 0.083 13.0 0.2 0.35 11.0 0.2 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus AsnC_trans_reg PF01037.21 AJA92383.1 - 9.8e-09 35.1 0.1 1.1e-08 34.9 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 AJA92383.1 - 0.021 14.9 0.9 0.054 13.6 0.9 1.6 1 1 0 1 1 1 0 NapD protein Ribosom_S12_S23 PF00164.25 AJA92384.1 - 3e-47 158.9 0.4 3.7e-47 158.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_23 PF13489.6 AJA92385.1 - 0.0094 15.8 0.0 0.016 15.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 AJA92385.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 AJA92385.1 - 0.056 12.8 0.1 0.091 12.2 0.1 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_25 PF13649.6 AJA92385.1 - 0.068 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TauE PF01925.19 AJA92386.1 - 9.3e-50 169.5 37.0 1.1e-49 169.2 37.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF2678 PF10856.8 AJA92386.1 - 0.073 13.0 0.5 0.073 13.0 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) S_4TM PF18159.1 AJA92386.1 - 0.12 11.6 0.4 0.27 10.5 0.4 1.6 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Glycos_transf_2 PF00535.26 AJA92387.1 - 1e-25 90.5 0.0 1.7e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AJA92387.1 - 2.4e-17 63.6 0.0 3.6e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AJA92387.1 - 0.00012 22.1 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_5 PF13712.6 AJA92387.1 - 0.00032 20.4 0.6 0.0023 17.6 0.6 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family Glyco_tranf_2_4 PF13704.6 AJA92387.1 - 0.15 12.6 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 AsnC_trans_reg PF01037.21 AJA92388.1 - 1.5e-11 44.1 0.0 2.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AJA92388.1 - 3.2e-11 42.6 1.9 7.5e-11 41.4 1.9 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AJA92388.1 - 6.9e-10 38.6 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 AJA92388.1 - 3.7e-06 26.8 0.2 5.5e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 AJA92388.1 - 0.00013 21.8 0.5 0.00029 20.7 0.5 1.6 1 0 0 1 1 1 1 HTH domain Ribosomal_S25 PF03297.15 AJA92388.1 - 0.0029 17.8 0.4 0.006 16.8 0.4 1.5 1 0 0 1 1 1 1 S25 ribosomal protein B-block_TFIIIC PF04182.12 AJA92388.1 - 0.0047 17.1 0.3 0.0089 16.2 0.3 1.5 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TrmB PF01978.19 AJA92388.1 - 0.023 14.5 0.9 0.059 13.3 0.2 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 AJA92388.1 - 0.026 14.6 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Mga PF05043.13 AJA92388.1 - 0.037 14.6 0.4 0.082 13.5 0.4 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain Rio2_N PF09202.11 AJA92388.1 - 0.043 14.0 0.2 0.1 12.9 0.2 1.7 1 1 0 1 1 1 0 Rio2, N-terminal HTH_34 PF13601.6 AJA92388.1 - 0.082 13.1 0.2 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR_2 PF12802.7 AJA92388.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 AJA92388.1 - 0.12 12.7 0.3 0.37 11.2 0.2 1.8 2 0 0 2 2 2 0 Transcriptional regulator BPD_transp_1 PF00528.22 AJA92389.1 - 3.5e-27 95.3 9.5 3.5e-27 95.3 9.5 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AJA92389.1 - 0.17 11.9 0.0 0.17 11.9 0.0 2.6 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C XPG_I PF00867.18 AJA92390.1 - 8.8e-23 80.5 0.0 2.6e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 AJA92390.1 - 2.1e-21 76.3 0.0 5.2e-21 75.0 0.0 1.6 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 AJA92390.1 - 0.001 19.6 0.0 0.0026 18.3 0.0 1.9 1 1 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF4878 PF12870.7 AJA92390.1 - 0.023 15.0 0.4 0.023 15.0 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) tRNA-synt_1g PF09334.11 AJA92392.1 - 3.7e-137 457.2 0.6 4.7e-137 456.9 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AJA92392.1 - 3.3e-20 71.9 1.0 4.2e-06 25.3 0.0 4.1 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AJA92392.1 - 5.7e-13 48.9 0.4 3.1e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 AJA92392.1 - 3.3e-08 33.6 0.3 9.5e-08 32.1 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 AJA92392.1 - 6.4e-06 25.3 0.1 0.01 14.8 0.0 3.2 3 0 0 3 3 3 1 tRNA synthetases class I (K) PolC_DP2 PF03833.13 AJA92392.1 - 0.018 12.9 1.1 0.025 12.5 1.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 FhuF PF06276.12 AJA92392.1 - 0.041 14.3 0.0 0.38 11.2 0.0 2.1 2 0 0 2 2 2 0 Ferric iron reductase FhuF-like transporter DUF3804 PF12707.7 AJA92392.1 - 0.078 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) DUF3010 PF11215.8 AJA92392.1 - 0.085 13.2 0.1 0.23 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) XhlA PF10779.9 AJA92392.1 - 0.12 12.5 0.2 0.33 11.2 0.2 1.7 1 0 0 1 1 1 0 Haemolysin XhlA Gene66 PF02053.15 AJA92392.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Gene 66 (IR5) protein zf-C3HC4_3 PF13920.6 AJA92392.1 - 0.84 9.6 8.1 1.4 8.8 0.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.12 AJA92392.1 - 1 9.9 6.9 3.2 8.3 6.7 1.9 1 1 0 1 1 1 0 CHY zinc finger zf-C2HC5 PF06221.13 AJA92392.1 - 1.1 9.3 9.1 2.7 8.1 1.5 2.4 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-Di19 PF05605.12 AJA92392.1 - 1.2 9.5 7.1 0.91 9.9 5.4 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 PF07191.12 AJA92392.1 - 1.2 9.1 7.2 4.1 7.5 7.0 1.8 1 1 0 1 1 1 0 zinc-ribbons DZR PF12773.7 AJA92392.1 - 2.8 8.0 10.6 4 7.5 6.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 AJA92392.1 - 5.9 6.9 7.5 8.1 6.5 0.4 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF424 PF04242.13 AJA92394.1 - 3.2e-20 72.2 0.1 3.6e-20 72.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF424) MethyltransfD12 PF02086.15 AJA92395.1 - 7e-65 219.3 2.6 8e-65 219.1 2.6 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase DUF2089 PF09862.9 AJA92395.1 - 0.039 14.0 0.1 0.096 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) ZnuA PF01297.17 AJA92395.1 - 0.12 11.8 0.3 0.18 11.2 0.0 1.4 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Sulfatase PF00884.23 AJA92396.1 - 5.1e-24 85.2 0.0 4.7e-23 82.1 0.0 2.4 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 AJA92396.1 - 7.1e-11 42.3 0.1 5.9e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 AJA92396.1 - 9e-05 22.7 0.7 0.00028 21.1 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Metalloenzyme PF01676.18 AJA92396.1 - 0.0019 17.6 0.0 0.0049 16.3 0.0 1.6 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF4994 PF16385.5 AJA92396.1 - 0.0037 17.2 2.7 0.0053 16.6 0.5 2.5 3 1 0 3 3 3 1 Domain of unknown function NUDIX PF00293.28 AJA92397.1 - 2.3e-10 40.6 0.0 2.7e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain CN_hydrolase PF00795.22 AJA92398.1 - 1.1e-54 185.6 0.0 1.2e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyoxalase_2 PF12681.7 AJA92399.1 - 1.9e-09 37.5 0.0 2.4e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 AJA92399.1 - 1.2e-08 35.2 0.0 2.1e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AJA92399.1 - 0.0015 19.3 0.0 0.0018 19.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AJA92399.1 - 0.015 15.6 0.0 4.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 AJA92399.1 - 0.15 12.2 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 CppA N-terminal PNP_UDP_1 PF01048.20 AJA92400.1 - 3.4e-46 157.4 0.0 3.9e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4368 PF14287.6 AJA92400.1 - 0.014 15.7 0.2 0.029 14.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) DUF1064 PF06356.11 AJA92400.1 - 0.17 12.3 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) ABC2_membrane PF01061.24 AJA92401.1 - 2.9e-32 111.8 20.7 2.9e-32 111.8 20.7 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AJA92401.1 - 1.3e-13 50.8 31.8 1.3e-13 50.8 31.8 1.2 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AJA92401.1 - 1.7e-06 27.6 28.1 5.1e-05 22.7 28.1 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein Acylphosphatase PF00708.18 AJA92403.1 - 1.1e-25 89.8 0.8 1.2e-25 89.7 0.8 1.0 1 0 0 1 1 1 1 Acylphosphatase SH3_13 PF18335.1 AJA92403.1 - 0.0068 16.2 0.6 0.01 15.6 0.6 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain DUF2871 PF11070.8 AJA92403.1 - 0.17 12.1 0.1 0.22 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2871) Big_3 PF07523.12 AJA92404.1 - 0.022 15.1 0.5 0.037 14.3 0.5 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) MBG_2 PF18676.1 AJA92404.1 - 0.065 13.9 0.2 4.4 8.0 0.1 2.4 2 0 0 2 2 2 0 MBG domain (YGX type) Metallophos PF00149.28 AJA92405.1 - 1.6e-17 64.7 0.6 2.4e-17 64.1 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AJA92405.1 - 1.5e-15 57.8 0.1 2.3e-15 57.2 0.1 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 AJA92405.1 - 3.4e-05 23.3 0.3 0.00013 21.4 0.2 2.0 1 1 1 3 3 3 1 Metallophosphoesterase, calcineurin superfamily DUF2124 PF09897.9 AJA92405.1 - 0.001 19.0 0.0 0.0024 17.8 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2124) MutL PF13941.6 AJA92405.1 - 0.078 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 MutL protein PBS_linker_poly PF00427.21 AJA92407.1 - 0.076 13.1 0.2 0.097 12.7 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Alba PF01918.21 AJA92408.1 - 8.7e-07 28.7 0.1 1.1e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Alba YycI PF09648.10 AJA92408.1 - 0.024 14.3 0.2 0.037 13.6 0.2 1.4 1 1 0 1 1 1 0 YycH protein MTS PF05175.14 AJA92408.1 - 0.062 12.8 0.1 0.083 12.4 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Band_7 PF01145.25 AJA92409.1 - 2.4e-24 86.3 5.9 3.8e-24 85.7 5.8 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family GFO_IDH_MocA PF01408.22 AJA92410.1 - 4.5e-20 72.7 0.0 7.6e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AJA92410.1 - 0.00089 19.3 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Rotamase_3 PF13616.6 AJA92411.1 - 1.8e-24 86.5 0.1 2.4e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AJA92411.1 - 2e-24 86.4 0.1 2.4e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AJA92411.1 - 2.8e-07 31.4 0.0 3.2e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain NTPase_I-T PF01931.18 AJA92411.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF84 UBA_2 PF08587.11 AJA92412.1 - 0.093 12.9 0.6 2.4 8.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Trm56 PF01994.16 AJA92413.1 - 1.7e-47 160.2 0.6 2.4e-47 159.8 0.6 1.2 1 0 0 1 1 1 1 tRNA ribose 2'-O-methyltransferase, aTrm56 SpoU_methylase PF00588.19 AJA92413.1 - 1.4e-05 25.2 0.1 2e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SPOUT_MTase_2 PF14419.6 AJA92413.1 - 0.0067 15.8 0.1 0.0081 15.5 0.1 1.3 1 1 0 1 1 1 1 AF2226-like SPOUT RNA Methylase fused to THUMP LSDAT_prok PF18171.1 AJA92413.1 - 0.022 14.0 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote DUF531 PF04407.12 AJA92413.1 - 0.09 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF531) WXG100 PF06013.12 AJA92413.1 - 0.18 12.0 0.0 0.56 10.5 0.0 1.8 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Trp_syntA PF00290.20 AJA92414.1 - 2.1e-81 272.6 1.1 2.3e-81 272.5 1.1 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 AJA92414.1 - 1.6e-07 31.0 0.7 2.1e-06 27.4 0.2 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 AJA92414.1 - 4.6e-06 25.9 0.3 4.1e-05 22.8 0.1 2.2 1 1 0 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 AJA92414.1 - 3.4e-05 23.2 4.2 5.7e-05 22.5 4.2 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Ribul_P_3_epim PF00834.19 AJA92414.1 - 4.5e-05 22.9 0.3 6.3e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family IGPS PF00218.21 AJA92414.1 - 0.00047 19.4 0.1 0.0028 16.9 0.1 2.0 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase IMPDH PF00478.25 AJA92414.1 - 0.0017 17.4 0.6 0.0053 15.8 0.5 1.8 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 AJA92414.1 - 0.011 15.0 0.6 0.024 14.0 0.6 1.6 1 1 0 1 1 1 0 Thiamine monophosphate synthase DUF871 PF05913.11 AJA92414.1 - 0.029 13.6 0.4 0.34 10.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF871) PucR PF07905.11 AJA92414.1 - 0.073 13.4 0.1 4.7 7.5 0.0 2.7 2 1 1 3 3 3 0 Purine catabolism regulatory protein-like family PcrB PF01884.17 AJA92414.1 - 0.13 11.7 3.1 0.47 9.9 0.9 2.7 2 1 1 3 3 3 0 PcrB family NeuB PF03102.14 AJA92415.1 - 4.9e-68 229.2 0.2 5.7e-68 229.0 0.2 1.0 1 0 0 1 1 1 1 NeuB family Ribonuc_red_lgC PF02867.15 AJA92416.1 - 3.6e-180 600.0 0.0 5.7e-180 599.3 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 AJA92416.1 - 1.2e-27 95.7 0.0 3.1e-27 94.4 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 AJA92416.1 - 1.1e-21 77.2 0.0 3e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain SecA_SW PF07516.13 AJA92416.1 - 0.16 12.0 0.7 0.92 9.5 0.0 2.4 3 0 0 3 3 3 0 SecA Wing and Scaffold domain HEPN_RES_NTD1 PF18870.1 AJA92416.1 - 0.31 11.2 1.5 5 7.3 0.0 3.4 4 0 0 4 4 4 0 HEPN/RES N-terminal domain 1 RNA_pol_A_bac PF01000.26 AJA92418.1 - 2e-22 79.6 0.0 4.6e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 AJA92418.1 - 3.1e-13 48.9 0.0 4e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Zip PF02535.22 AJA92419.1 - 4.2e-05 22.9 19.3 4.2e-05 22.9 19.3 2.3 1 1 1 2 2 2 1 ZIP Zinc transporter LapA_dom PF06305.11 AJA92419.1 - 0.0051 16.6 0.6 0.0051 16.6 0.6 5.1 5 2 2 7 7 7 1 Lipopolysaccharide assembly protein A domain Saccharop_dh_N PF04455.12 AJA92420.1 - 1e-32 112.5 0.3 4.5e-32 110.4 0.3 2.1 2 0 0 2 2 2 1 LOR/SDH bifunctional enzyme conserved region TPP_enzyme_M PF00205.22 AJA92420.1 - 0.0019 17.9 1.5 0.096 12.4 0.1 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Citrate_bind PF16114.5 AJA92420.1 - 0.003 17.1 0.2 0.0098 15.4 0.1 1.8 2 0 0 2 2 2 1 ATP citrate lyase citrate-binding DS PF01916.17 AJA92420.1 - 0.0085 15.4 2.5 0.048 12.9 0.5 2.6 1 1 1 3 3 3 1 Deoxyhypusine synthase Gar1 PF04410.14 AJA92422.1 - 7.3e-08 32.3 0.0 7.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF1668 PF07893.13 AJA92422.1 - 0.17 11.2 0.0 0.18 11.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) ThiC_Rad_SAM PF01964.18 AJA92423.1 - 8e-170 565.1 0.4 9.2e-170 564.9 0.4 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family Spore_GerAC PF05504.11 AJA92423.1 - 0.052 13.8 3.1 0.063 13.5 1.2 2.0 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal TP_methylase PF00590.20 AJA92424.1 - 7.8e-38 130.6 0.0 9.2e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases YdjM PF04307.14 AJA92425.1 - 0.00015 21.1 7.2 0.00018 20.9 6.3 1.7 1 1 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase FAM165 PF14981.6 AJA92426.1 - 0.0021 17.8 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 FAM165 family TMEM154 PF15102.6 AJA92426.1 - 0.1 12.5 0.1 0.11 12.4 0.1 1.0 1 0 0 1 1 1 0 TMEM154 protein family CDP-OH_P_transf PF01066.21 AJA92427.1 - 1.9e-10 41.4 0.8 1.9e-10 41.4 0.8 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ECSCR PF15820.5 AJA92427.1 - 0.19 11.6 2.1 0.35 10.7 2.1 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Gln-synt_C PF00120.24 AJA92428.1 - 1.9e-115 385.5 0.0 2.3e-115 385.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AJA92428.1 - 1e-27 95.7 0.1 2.4e-27 94.5 0.1 1.7 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF2527 PF10736.9 AJA92428.1 - 0.3 11.0 2.9 3 7.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) Ribosomal_S27e PF01667.17 AJA92429.1 - 1e-16 60.4 0.9 1.1e-16 60.2 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 AJA92429.1 - 1.3e-06 27.8 0.8 1.7e-06 27.4 0.8 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding Zn_Tnp_IS91 PF14319.6 AJA92429.1 - 0.00046 20.2 0.7 0.00047 20.1 0.7 1.1 1 0 0 1 1 1 1 Transposase zinc-binding domain DUF2318 PF10080.9 AJA92429.1 - 0.0024 17.9 0.4 0.0027 17.8 0.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) zf-RING_9 PF13901.6 AJA92429.1 - 0.0056 16.7 0.9 0.0056 16.7 0.9 1.1 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon ZZ PF00569.17 AJA92429.1 - 0.017 14.9 3.5 2.1 8.2 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type RNA_POL_M_15KD PF02150.16 AJA92429.1 - 0.027 14.4 0.4 7.4 6.5 0.0 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C2H2_7 PF15269.6 AJA92429.1 - 0.061 13.4 0.6 0.073 13.2 0.6 1.1 1 0 0 1 1 1 0 Zinc-finger A2L_zn_ribbon PF08792.10 AJA92429.1 - 0.12 12.1 5.6 0.24 11.2 5.6 1.4 1 1 0 1 1 1 0 A2L zinc ribbon domain zinc_ribbon_6 PF14599.6 AJA92429.1 - 0.14 12.2 4.4 0.53 10.4 4.5 1.7 1 1 1 2 2 2 0 Zinc-ribbon zinc_ribbon_9 PF14369.6 AJA92429.1 - 0.16 12.3 3.9 0.25 11.6 3.9 1.3 1 0 0 1 1 1 0 zinc-ribbon zf-BED PF02892.15 AJA92429.1 - 0.16 12.0 0.7 0.16 12.0 0.7 2.1 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_3 PF13878.6 AJA92429.1 - 2 8.3 5.8 2.2 8.2 1.4 2.2 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO Amidohydro_1 PF01979.20 AJA92430.1 - 7.8e-38 130.7 0.2 9.4e-38 130.4 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AJA92430.1 - 1.3e-11 44.7 0.0 7.6e-06 25.7 0.0 2.3 1 1 0 2 2 2 2 Amidohydrolase family RIO1 PF01163.22 AJA92431.1 - 5.4e-47 159.8 0.0 8.4e-47 159.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family RSB_motif PF16294.5 AJA92431.1 - 0.8 10.0 6.0 4.1 7.7 3.4 2.2 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif MerT PF02411.15 AJA92432.1 - 0.021 14.9 0.6 0.025 14.6 0.6 1.1 1 0 0 1 1 1 0 MerT mercuric transport protein HAD_2 PF13419.6 AJA92433.1 - 2.1e-11 44.2 0.1 9.9e-10 38.8 0.1 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PNK3P PF08645.11 AJA92433.1 - 1.2e-10 41.3 0.2 1.4e-10 41.2 0.2 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase_like PF13242.6 AJA92433.1 - 1.6e-10 40.9 0.0 2.5e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 AJA92433.1 - 7.3e-06 26.4 0.0 1e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AJA92433.1 - 0.00012 22.5 0.0 0.00015 22.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AJA92433.1 - 0.0031 17.6 0.1 0.0051 16.9 0.1 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AJA92433.1 - 0.012 15.3 3.6 0.09 12.5 0.2 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_SAK_2 PF18143.1 AJA92433.1 - 0.058 13.7 0.0 0.075 13.3 0.0 1.3 1 1 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins 5TM-5TMR_LYT PF07694.12 AJA92434.1 - 0.012 15.2 0.1 0.012 15.1 0.1 1.0 1 0 0 1 1 1 0 5TMR of 5TMR-LYT CobA_CobO_BtuR PF02572.15 AJA92435.1 - 4.7e-65 219.0 0.2 5.2e-65 218.9 0.2 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_14 PF13173.6 AJA92435.1 - 0.0049 16.9 0.5 0.0066 16.5 0.5 1.4 1 1 0 1 1 1 1 AAA domain DUF2938 PF11158.8 AJA92436.1 - 0.036 13.5 2.0 0.72 9.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2938) DUF3021 PF11457.8 AJA92436.1 - 0.082 13.2 4.3 0.63 10.4 4.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) Peptidase_M56 PF05569.11 AJA92436.1 - 0.14 11.4 1.5 0.16 11.1 1.5 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 FeoB_C PF07664.12 AJA92436.1 - 0.18 11.5 4.0 2.5 7.8 0.4 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus HTH_24 PF13412.6 AJA92437.1 - 6.4e-10 38.4 8.2 1.6e-05 24.4 2.7 2.9 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AJA92437.1 - 6.4e-08 32.3 1.3 7.1e-05 22.6 0.4 2.7 3 0 0 3 3 3 2 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 AJA92437.1 - 6e-05 22.8 0.8 0.011 15.5 0.0 2.7 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AJA92437.1 - 6.9e-05 22.7 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 2 MarR family HTH_41 PF14502.6 AJA92437.1 - 0.00014 21.5 0.3 0.012 15.3 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.22 AJA92437.1 - 0.0037 17.2 1.0 1.1 9.2 0.4 2.5 2 0 0 2 2 2 2 MarR family DUF1280 PF06918.14 AJA92437.1 - 0.0042 16.7 2.6 0.0057 16.3 0.8 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1280) TrmB PF01978.19 AJA92437.1 - 0.011 15.6 0.0 0.058 13.3 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 AJA92437.1 - 0.021 14.8 0.9 0.54 10.2 0.2 2.7 3 0 0 3 3 3 0 HTH domain Mga PF05043.13 AJA92437.1 - 0.033 14.8 0.3 0.093 13.3 0.3 1.9 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_36 PF13730.6 AJA92437.1 - 0.12 12.3 0.6 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain CbiX PF01903.17 AJA92437.1 - 0.15 12.4 0.0 4.3 7.7 0.0 2.4 2 0 0 2 2 2 0 CbiX GvpK PF05121.12 AJA92437.1 - 0.43 10.7 3.8 1.2 9.2 3.8 1.7 1 1 0 1 1 1 0 Gas vesicle protein K HTH_DeoR PF08220.12 AJA92437.1 - 2.3 8.0 4.8 0.52 10.1 0.3 2.3 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain vATP-synt_AC39 PF01992.16 AJA92438.1 - 1.7e-52 179.1 7.7 2.2e-52 178.7 7.7 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Rieske PF00355.26 AJA92439.1 - 9.6e-20 70.3 0.1 1.3e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AJA92439.1 - 7e-08 32.4 0.0 8.2e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain TFIIB PF00382.19 AJA92440.1 - 1.4e-37 127.5 2.6 3.3e-18 65.5 0.2 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJA92440.1 - 9.8e-12 44.2 0.4 1.6e-11 43.5 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 AJA92440.1 - 3.7e-05 23.5 0.1 0.0029 17.4 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ribosomal_S27e PF01667.17 AJA92440.1 - 0.0025 17.5 0.5 0.0052 16.5 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 zf-ribbon_3 PF13248.6 AJA92440.1 - 0.0027 17.0 2.6 0.02 14.3 2.6 2.2 1 1 0 1 1 1 1 zinc-ribbon domain HTH_Mga PF08280.11 AJA92440.1 - 0.0083 16.1 0.8 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain TFIIB_C_1 PF18542.1 AJA92440.1 - 0.01 15.9 1.2 0.023 14.7 0.5 1.9 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 RB_B PF01857.20 AJA92440.1 - 0.015 15.3 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain RPA_interact_C PF14768.6 AJA92440.1 - 0.022 15.3 0.2 0.044 14.4 0.2 1.7 1 1 0 1 1 1 0 Replication protein A interacting C-terminal HTH_11 PF08279.12 AJA92440.1 - 0.036 14.0 0.3 0.19 11.7 0.0 2.2 3 0 0 3 3 3 0 HTH domain Sigma70_r4 PF04545.16 AJA92440.1 - 0.055 13.0 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HMG_CoA_synt_C PF08540.10 AJA92440.1 - 0.074 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal Auto_anti-p27 PF06677.12 AJA92440.1 - 0.079 13.1 1.3 0.15 12.2 1.3 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MCPVI PF02993.14 AJA92440.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Cyclin_C PF02984.19 AJA92440.1 - 0.11 12.6 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain Sigma70_r4_2 PF08281.12 AJA92440.1 - 0.15 11.8 0.5 0.77 9.5 0.1 2.3 3 0 0 3 3 3 0 Sigma-70, region 4 Pyridox_ox_2 PF12900.7 AJA92441.1 - 1.4e-20 73.7 0.0 1.9e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 AJA92441.1 - 7.5e-10 38.9 0.0 1.7e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ParD_antitoxin PF03693.14 AJA92441.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH TPR_1 PF00515.28 AJA92442.1 - 1.8e-12 46.5 2.6 1.1e-05 25.0 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AJA92442.1 - 2.2e-11 43.0 0.4 0.00023 21.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Peptidase_M10 PF00413.24 AJA92442.1 - 5.1e-10 39.4 0.7 3.8e-09 36.6 0.7 2.1 1 1 0 1 1 1 1 Matrixin TPR_8 PF13181.6 AJA92442.1 - 4e-08 32.8 2.4 0.021 15.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Reprolysin_5 PF13688.6 AJA92442.1 - 4.2e-07 30.3 0.0 8.5e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 TPR_12 PF13424.6 AJA92442.1 - 4.4e-07 30.1 0.1 0.0084 16.4 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Peptidase_M57 PF12388.8 AJA92442.1 - 8.5e-07 28.8 0.1 1.7e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase TPR_11 PF13414.6 AJA92442.1 - 5e-06 26.1 0.5 0.011 15.4 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 AJA92442.1 - 8.6e-06 26.2 0.0 0.6 11.1 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AJA92442.1 - 1.7e-05 24.5 0.1 0.093 12.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJA92442.1 - 5.5e-05 23.2 0.4 0.26 11.4 0.0 2.8 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 AJA92442.1 - 0.00016 22.1 0.3 0.72 10.4 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 AJA92442.1 - 0.00075 20.1 0.0 0.11 13.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Peptidase_M54 PF07998.11 AJA92442.1 - 0.0064 16.5 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_3 PF13582.6 AJA92442.1 - 0.014 16.0 0.5 0.036 14.6 0.5 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Alkyl_sulf_dimr PF14863.6 AJA92442.1 - 0.021 15.3 0.0 0.053 14.0 0.0 1.6 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation TPR_17 PF13431.6 AJA92442.1 - 0.024 15.0 0.7 2.6 8.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 AJA92442.1 - 0.024 15.2 0.0 8.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AJA92442.1 - 0.035 14.3 1.8 2.7 8.3 0.0 2.6 2 1 1 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 AJA92442.1 - 0.093 12.6 0.2 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Reprolysin_2 PF13574.6 AJA92442.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like TPR_3 PF07720.12 AJA92442.1 - 0.17 11.9 6.4 0.5 10.4 0.2 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Peptidase_M66 PF10462.9 AJA92442.1 - 0.18 10.8 1.8 0.31 10.0 1.8 1.3 1 0 0 1 1 1 0 Peptidase M66 DNA_primase_lrg PF04104.14 AJA92443.1 - 1.3e-22 80.4 0.3 2.8e-22 79.4 0.3 1.6 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit adh_short PF00106.25 AJA92444.1 - 1.3e-65 220.5 1.6 1.6e-65 220.2 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AJA92444.1 - 1.9e-46 158.5 0.9 2.3e-46 158.3 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJA92444.1 - 6.9e-17 61.9 0.2 8.8e-17 61.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AJA92444.1 - 6.5e-05 22.5 0.9 0.00033 20.2 0.3 2.3 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AJA92444.1 - 0.00046 20.1 1.1 0.001 19.0 0.5 1.7 1 1 1 2 2 2 1 NAD(P)H-binding ClpB_D2-small PF10431.9 AJA92444.1 - 0.033 14.3 0.2 0.55 10.3 0.1 2.3 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein NmrA PF05368.13 AJA92444.1 - 0.096 12.2 1.1 0.3 10.6 0.3 1.9 2 0 0 2 2 2 0 NmrA-like family POR_N PF01855.19 AJA92445.1 - 1.7e-54 185.0 0.0 2.4e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 AJA92445.1 - 4.6e-32 111.5 0.2 8.2e-32 110.7 0.2 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 AJA92445.1 - 2.5e-14 53.4 0.0 6.1e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 AJA92445.1 - 1.6e-07 31.3 0.0 3.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_N PF02776.18 AJA92445.1 - 0.0014 18.3 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain PUL PF08324.11 AJA92445.1 - 0.13 11.5 0.5 0.22 10.7 0.5 1.3 1 0 0 1 1 1 0 PUL domain FAD_binding_2 PF00890.24 AJA92447.1 - 6.3e-99 331.9 0.2 7.8e-99 331.6 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AJA92447.1 - 2.1e-34 118.3 0.4 3.3e-34 117.6 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AJA92447.1 - 8.5e-07 28.5 0.0 1.6e-05 24.3 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AJA92447.1 - 0.0011 18.1 0.1 0.1 11.7 0.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 AJA92447.1 - 0.0022 16.8 1.1 0.86 8.2 0.6 2.5 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 AJA92447.1 - 0.0049 16.2 0.7 0.025 13.8 0.2 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 AJA92447.1 - 0.015 14.7 0.2 0.21 10.9 0.3 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AJA92447.1 - 0.074 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF5557 PF17712.1 AJA92448.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5557) DsbD PF02683.15 AJA92449.1 - 2.3e-48 164.9 19.7 2.6e-48 164.7 19.7 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region NadA PF02445.16 AJA92450.1 - 2.5e-113 378.2 5.0 2.9e-113 378.0 5.0 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein DegT_DnrJ_EryC1 PF01041.17 AJA92451.1 - 1.9e-103 346.6 0.0 2.2e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AJA92451.1 - 0.0015 17.9 0.2 0.011 15.0 0.2 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AJA92451.1 - 0.039 12.5 0.0 0.063 11.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PALP PF00291.25 AJA92451.1 - 0.14 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Pterin_4a PF01329.19 AJA92452.1 - 6.9e-28 96.7 0.1 7.6e-28 96.5 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.8 AJA92452.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Translation-initiation factor 2 ATP-synt_ab PF00006.25 AJA92453.1 - 1.9e-68 230.3 0.0 2.6e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AJA92453.1 - 8e-12 45.5 3.7 2.8e-11 43.8 3.1 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 AJA92453.1 - 0.00094 19.3 0.8 0.0031 17.6 0.8 1.9 1 0 0 1 1 1 1 HAS barrel domain DUF2779 PF11074.8 AJA92453.1 - 0.18 12.3 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) tRNA-synt_1f PF01921.18 AJA92454.1 - 1.3e-106 356.6 0.0 1.8e-106 356.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1g PF09334.11 AJA92454.1 - 0.011 14.5 1.1 0.083 11.6 0.0 2.4 1 1 2 3 3 3 0 tRNA synthetases class I (M) THUMP PF02926.17 AJA92454.1 - 0.042 13.9 0.8 6.4 6.9 0.1 2.8 2 1 0 2 2 2 0 THUMP domain tRNA-synt_1 PF00133.22 AJA92454.1 - 0.056 11.7 0.0 0.11 10.7 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) PolyA_pol_RNAbd PF12627.7 AJA92454.1 - 0.08 12.7 0.5 0.24 11.2 0.1 2.0 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A tRNA-synt_1e PF01406.19 AJA92454.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain UPF0047 PF01894.17 AJA92455.1 - 2.3e-37 127.7 0.0 2.6e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 RimK PF08443.11 AJA92456.1 - 2.1e-32 112.2 0.0 3.4e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 AJA92456.1 - 2.7e-06 26.9 0.0 3.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 AJA92456.1 - 4.1e-06 26.9 0.0 6.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AJA92456.1 - 8.6e-05 22.1 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.6 AJA92456.1 - 0.0024 17.2 0.1 0.14 11.4 0.0 2.8 1 1 2 3 3 3 1 Sugar-transfer associated ATP-grasp ATP-grasp PF02222.22 AJA92456.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain Synapsin_C PF02750.14 AJA92456.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Synapsin, ATP binding domain ATPgrasp_YheCD PF14398.6 AJA92456.1 - 0.021 14.1 0.0 0.52 9.5 0.0 2.4 1 1 2 3 3 3 0 YheC/D like ATP-grasp ATP-grasp_5 PF13549.6 AJA92456.1 - 0.096 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Methyltransf_25 PF13649.6 AJA92457.1 - 3.3e-16 59.8 0.0 9.3e-16 58.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJA92457.1 - 1.3e-15 57.6 0.0 1.7e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJA92457.1 - 1.4e-15 57.4 0.0 1.6e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJA92457.1 - 3.2e-14 53.4 0.0 5.3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJA92457.1 - 5.7e-12 46.2 0.0 8.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AJA92457.1 - 1.3e-08 34.2 0.1 2.8e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) NodS PF05401.11 AJA92457.1 - 2.7e-08 33.7 0.0 3.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 AJA92457.1 - 2.9e-08 33.4 0.0 9e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase CMAS PF02353.20 AJA92457.1 - 8.3e-08 31.8 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 AJA92457.1 - 4.3e-06 26.4 0.1 5.2e-05 22.9 0.1 2.0 1 1 1 2 2 2 1 Histone methylation protein DOT1 MTS PF05175.14 AJA92457.1 - 1.8e-05 24.4 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 AJA92457.1 - 5e-05 22.7 0.2 0.00024 20.5 0.0 1.9 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 AJA92457.1 - 6.2e-05 22.8 0.0 8.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 AJA92457.1 - 0.0001 22.0 0.0 0.00019 21.1 0.0 1.4 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 AJA92457.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 AJA92457.1 - 0.0018 17.5 0.1 0.0074 15.4 0.1 1.9 1 1 0 1 1 1 1 mRNA capping enzyme PrmA PF06325.13 AJA92457.1 - 0.0029 17.0 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 AJA92457.1 - 0.0031 17.5 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 AJA92457.1 - 0.0039 16.3 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase CheR PF01739.18 AJA92457.1 - 0.0078 15.7 0.0 1.2 8.6 0.0 2.5 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_5 PF01795.19 AJA92457.1 - 0.012 15.1 0.0 0.032 13.7 0.0 1.6 2 0 0 2 2 2 0 MraW methylase family RrnaAD PF00398.20 AJA92457.1 - 0.022 13.8 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase AdoMet_MTase PF07757.13 AJA92457.1 - 0.023 15.0 0.0 0.064 13.6 0.0 1.8 2 0 0 2 2 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_2 PF00891.18 AJA92457.1 - 0.028 13.7 0.0 0.49 9.6 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase domain TehB PF03848.14 AJA92457.1 - 0.079 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Formyl_trans_N PF00551.19 AJA92458.1 - 8e-52 175.6 0.1 9.3e-52 175.4 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase SWIM PF04434.17 AJA92461.1 - 0.0073 15.9 0.6 0.012 15.3 0.6 1.3 1 0 0 1 1 1 1 SWIM zinc finger tRNA-synt_1c_C PF03950.18 AJA92462.1 - 0.024 14.5 0.1 0.028 14.3 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Epimerase PF01370.21 AJA92463.1 - 1.5e-13 50.8 0.0 1.9e-11 43.9 0.0 2.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AJA92463.1 - 5.2e-09 35.5 2.4 8.7e-06 24.9 0.1 3.4 2 1 1 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AJA92463.1 - 6.7e-09 35.9 0.0 2.3e-07 30.9 0.0 2.1 1 1 1 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AJA92463.1 - 1.5e-08 34.2 0.5 0.0012 18.0 0.0 2.9 1 1 2 3 3 3 2 Male sterility protein RmlD_sub_bind PF04321.17 AJA92463.1 - 3.5e-06 26.3 0.0 0.00022 20.5 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 AJA92463.1 - 0.00048 19.8 0.0 0.0074 15.9 0.0 2.0 1 1 1 2 2 2 1 NmrA-like family MSV199 PF10553.9 AJA92463.1 - 0.034 14.4 2.2 0.045 14.0 0.3 2.2 2 1 0 2 2 2 0 MSV199 domain PAC2 PF09754.9 AJA92463.1 - 0.069 13.1 0.0 0.12 12.4 0.0 1.3 1 1 0 1 1 1 0 PAC2 family GDP_Man_Dehyd PF16363.5 AJA92463.1 - 0.092 12.1 0.1 0.39 10.1 0.0 1.9 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase NTP_transferase PF00483.23 AJA92464.1 - 2.3e-25 89.6 0.1 3.6e-25 89.0 0.1 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AJA92464.1 - 0.00027 21.3 0.0 0.00035 21.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Prot_ATP_ID_OB PF16450.5 AJA92464.1 - 0.17 11.9 0.1 0.44 10.5 0.1 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Ribosomal_S5 PF00333.20 AJA92465.1 - 3.6e-22 78.1 0.3 6.3e-22 77.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 AJA92465.1 - 1.1e-14 53.6 0.1 1.8e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DOMON PF03351.17 AJA92465.1 - 0.19 11.9 0.1 0.38 11.0 0.1 1.4 1 0 0 1 1 1 0 DOMON domain TDP43_N PF18694.1 AJA92466.1 - 0.13 12.1 0.0 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain NTP_transf_9 PF04248.12 AJA92467.1 - 4.2e-32 109.9 1.5 4.6e-32 109.8 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) ERCC4 PF02732.15 AJA92468.1 - 4.6e-24 85.4 0.0 8.2e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 AJA92468.1 - 4.7e-08 33.5 0.1 1.8e-07 31.7 0.1 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 AJA92468.1 - 0.0042 17.2 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 AJA92468.1 - 0.0048 16.7 0.9 4 7.5 0.2 3.0 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_3 PF12836.7 AJA92468.1 - 0.015 15.5 0.1 0.13 12.6 0.0 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 AJA92468.1 - 0.022 15.4 0.2 0.074 13.7 0.1 1.9 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold HHH_8 PF14716.6 AJA92468.1 - 0.072 13.5 0.1 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain HpaB_N PF11794.8 AJA92469.1 - 1.4e-94 316.8 0.0 2.3e-94 316.1 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 AJA92469.1 - 3.5e-73 245.0 0.7 5e-73 244.5 0.7 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal zf-Tim10_DDP PF02953.15 AJA92469.1 - 0.15 11.7 0.1 0.33 10.6 0.1 1.5 1 0 0 1 1 1 0 Tim10/DDP family zinc finger tRNA-synt_2 PF00152.20 AJA92470.1 - 6.5e-87 291.5 0.0 8.2e-87 291.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AJA92470.1 - 1.6e-12 47.2 0.2 3e-12 46.3 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AJA92470.1 - 0.00048 19.7 0.6 0.098 12.1 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Dysbindin PF04440.16 AJA92470.1 - 0.16 12.2 0.8 0.3 11.3 0.3 1.6 2 0 0 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) PdaC PF13739.6 AJA92471.1 - 0.074 14.0 0.3 0.12 13.3 0.1 1.5 2 0 0 2 2 2 0 Deacetylase PdaC DUF5343 PF17278.2 AJA92471.1 - 0.1 12.7 0.0 0.76 9.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5343) Glutaredoxin2_C PF04399.13 AJA92472.1 - 0.25 11.2 1.3 7.6 6.4 0.1 2.8 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain HTH_45 PF14947.6 AJA92473.1 - 2.4e-11 43.4 0.1 3e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.7 AJA92473.1 - 5.8e-06 26.1 0.0 7.4e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AJA92473.1 - 0.00026 21.4 0.0 0.00034 21.0 0.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4364 PF14277.6 AJA92473.1 - 0.0084 15.9 0.0 0.0093 15.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_20 PF12840.7 AJA92473.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 AJA92473.1 - 0.048 13.5 0.0 0.086 12.7 0.0 1.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Mrr_N PF14338.6 AJA92473.1 - 0.071 13.3 0.0 0.23 11.6 0.0 1.8 1 1 1 2 2 2 0 Mrr N-terminal domain Rrf2 PF02082.20 AJA92473.1 - 0.073 13.4 0.0 0.098 13.0 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator DUF1495 PF07381.11 AJA92473.1 - 0.09 12.6 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) ATP-sulfurylase PF01747.17 AJA92474.1 - 1.3e-84 282.9 0.2 2.5e-84 282.0 0.2 1.4 2 0 0 2 2 2 1 ATP-sulfurylase PUA_2 PF14306.6 AJA92474.1 - 9e-44 148.9 0.0 1.7e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain DUF1415 PF07209.12 AJA92474.1 - 0.091 12.5 0.1 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) EpsG PF14897.6 AJA92475.1 - 0.037 13.3 0.2 0.049 12.9 0.2 1.1 1 0 0 1 1 1 0 EpsG family ASH PF15780.5 AJA92475.1 - 0.063 13.5 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin RNase_HII PF01351.18 AJA92476.1 - 6.5e-42 143.6 0.6 7.5e-42 143.4 0.6 1.0 1 0 0 1 1 1 1 Ribonuclease HII Dioxygenase_N PF04444.14 AJA92477.1 - 0.21 11.5 0.1 0.71 9.8 0.1 1.8 2 0 0 2 2 2 0 Catechol dioxygenase N terminus Lactamase_B PF00753.27 AJA92478.1 - 6.2e-19 68.8 1.7 7.6e-18 65.2 1.7 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AJA92478.1 - 0.052 13.1 0.1 0.076 12.5 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Rhomboid PF01694.22 AJA92479.1 - 5.6e-32 110.8 21.8 5.6e-32 110.8 21.8 1.5 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 AJA92479.1 - 0.031 14.8 1.2 0.14 12.7 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Fer4 PF00037.27 AJA92480.1 - 1.6e-10 40.3 11.1 2.9e-05 23.7 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJA92480.1 - 4.9e-09 36.6 3.2 6.9e-09 36.2 3.2 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJA92480.1 - 1.7e-08 34.4 1.5 2.5e-08 33.9 1.5 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AJA92480.1 - 2.4e-07 30.5 9.9 0.00026 20.9 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AJA92480.1 - 5.9e-06 26.1 9.0 0.0023 17.9 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AJA92480.1 - 6.8e-06 26.5 4.5 0.0038 17.7 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_9 PF13187.6 AJA92480.1 - 1.2e-05 25.3 4.7 7.2e-05 22.9 5.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJA92480.1 - 1.4e-05 25.1 8.4 0.00018 21.6 9.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AJA92480.1 - 6.6e-05 23.1 7.1 0.019 15.4 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AJA92480.1 - 0.00071 20.5 5.5 0.27 12.2 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 AJA92480.1 - 0.0018 19.1 2.7 0.44 11.4 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AJA92480.1 - 0.002 18.5 6.6 0.015 15.8 6.6 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 AJA92480.1 - 0.0025 18.6 10.6 0.087 13.8 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 AJA92480.1 - 0.0038 17.9 10.4 0.0061 17.3 2.2 2.3 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_17 PF13534.6 AJA92480.1 - 0.015 15.9 7.2 0.42 11.2 7.1 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AJA92480.1 - 0.93 9.7 10.3 1.8 8.8 2.7 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Cas_Cmr5 PF09701.10 AJA92481.1 - 0.0049 17.2 0.1 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 CRISPR-associated protein (Cas_Cmr5) CAT_RBD PF03123.15 AJA92481.1 - 0.006 16.5 0.2 0.014 15.3 0.2 1.5 1 0 0 1 1 1 1 CAT RNA binding domain zf-RRN7 PF11781.8 AJA92482.1 - 0.49 10.1 5.1 0.41 10.4 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 CarboxypepD_reg PF13620.6 AJA92483.1 - 0.0029 17.8 0.0 0.0064 16.7 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Y_Y_Y PF07495.13 AJA92483.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Y_Y_Y domain Toprim_4 PF13662.6 AJA92485.1 - 2.5e-08 34.3 0.7 6e-08 33.0 0.3 2.0 2 0 0 2 2 2 1 Toprim domain Toprim_2 PF13155.6 AJA92485.1 - 7.6e-06 26.3 0.2 2.6e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Toprim-like Toprim PF01751.22 AJA92485.1 - 0.015 15.5 0.1 0.05 13.8 0.1 2.0 1 1 0 1 1 1 0 Toprim domain MIP PF00230.20 AJA92487.1 - 1.8e-38 132.5 18.5 2.2e-38 132.2 18.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein TruB_N PF01509.18 AJA92488.1 - 2.8e-25 89.4 0.3 2.1e-14 54.1 0.0 3.4 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AJA92488.1 - 8.8e-20 70.6 0.0 2.7e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 AJA92488.1 - 1.1e-13 50.9 0.1 2e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 PUA domain DKCLD PF08068.12 AJA92488.1 - 1.8e-12 47.1 0.0 5.4e-12 45.6 0.1 1.8 2 0 0 2 2 2 1 DKCLD (NUC011) domain Na_H_Exchanger PF00999.21 AJA92489.1 - 1.2e-59 202.1 49.7 1.5e-59 201.8 49.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Metallothio PF00131.20 AJA92490.1 - 0.0013 18.8 13.8 0.0013 18.8 13.8 2.0 1 1 1 2 2 2 1 Metallothionein AhpC-TSA PF00578.21 AJA92491.1 - 4.2e-35 120.4 0.2 4.8e-35 120.2 0.2 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJA92491.1 - 3.6e-25 88.4 0.1 4.4e-25 88.1 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 AJA92491.1 - 3.5e-07 30.3 0.0 4.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.6 AJA92491.1 - 0.00065 20.0 0.0 0.00082 19.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DUF899 PF05988.12 AJA92491.1 - 0.00093 18.8 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) SCO1-SenC PF02630.14 AJA92491.1 - 0.0015 18.4 0.0 0.0028 17.6 0.0 1.5 1 1 0 1 1 1 1 SCO1/SenC CUTL PF16557.5 AJA92491.1 - 0.014 15.6 0.9 1.6 9.0 0.0 2.5 3 0 0 3 3 3 0 CUT1-like DNA-binding domain of SATB DUF3986 PF13143.6 AJA92491.1 - 0.066 14.2 0.1 0.11 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3986) FtsQ PF03799.15 AJA92491.1 - 0.14 13.0 0.0 0.7 10.7 0.0 1.8 2 0 0 2 2 2 0 Cell division protein FtsQ zinc_ribbon_2 PF13240.6 AJA92492.1 - 1.5e-07 30.9 5.0 2.9e-07 30.0 5.0 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 AJA92492.1 - 6.8e-07 28.5 2.4 1e-06 27.9 2.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AJA92492.1 - 2.8e-06 27.2 1.4 4.1e-06 26.7 1.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 AJA92492.1 - 0.0017 19.1 1.3 0.0023 18.6 1.3 1.2 1 0 0 1 1 1 1 zinc-ribbon family GFA PF04828.14 AJA92492.1 - 0.0041 17.4 1.7 0.33 11.3 0.1 2.3 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 AJA92492.1 - 0.0058 16.5 4.5 1.1 9.3 0.3 2.4 2 0 0 2 2 2 2 Nudix N-terminal DHHC PF01529.20 AJA92492.1 - 0.014 15.5 0.7 0.021 14.9 0.7 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase zf-NADH-PPase PF09297.11 AJA92492.1 - 0.2 11.3 4.5 0.44 10.2 4.5 1.5 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain RNA_POL_M_15KD PF02150.16 AJA92492.1 - 0.28 11.1 5.6 6.1 6.8 0.3 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit UPF0547 PF10571.9 AJA92492.1 - 0.4 10.8 5.9 5.3 7.2 0.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF2321 PF10083.9 AJA92492.1 - 0.79 9.3 3.8 2.9 7.5 3.8 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) NOB1_Zn_bind PF08772.11 AJA92492.1 - 1.2 9.4 7.0 3.4 7.9 0.7 2.5 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like LSM PF01423.22 AJA92493.1 - 7.6e-24 83.2 0.2 8.5e-24 83.0 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 AJA92493.1 - 0.0037 17.4 0.1 0.0045 17.1 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 AJA92493.1 - 0.039 13.6 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Hfq protein RTBV_P12 PF06361.11 AJA92493.1 - 0.07 13.5 0.0 0.079 13.4 0.0 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein BPL_C PF02237.17 AJA92493.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.5 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain DUF150_C PF17384.2 AJA92493.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain HTH_24 PF13412.6 AJA92494.1 - 5.9e-10 38.6 3.7 2.9e-05 23.5 1.9 2.9 2 1 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AJA92494.1 - 2.6e-09 36.8 0.1 0.0026 17.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AJA92494.1 - 2.5e-05 24.1 0.0 0.087 12.7 0.0 2.1 2 0 0 2 2 2 2 MarR family TrmB PF01978.19 AJA92494.1 - 3e-05 23.8 0.7 0.034 14.0 0.0 2.2 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB RepL PF05732.11 AJA92494.1 - 8.9e-05 22.0 6.4 0.00011 21.6 6.1 1.4 1 1 0 1 1 1 1 Firmicute plasmid replication protein (RepL) MarR PF01047.22 AJA92494.1 - 0.00091 19.1 0.4 0.043 13.8 0.2 2.2 2 0 0 2 2 2 1 MarR family HTH_34 PF13601.6 AJA92494.1 - 0.0018 18.4 0.7 1.3 9.3 0.3 2.3 2 0 0 2 2 2 2 Winged helix DNA-binding domain Rrf2 PF02082.20 AJA92494.1 - 0.0048 17.2 0.7 2 8.8 0.1 2.4 2 0 0 2 2 2 2 Transcriptional regulator HTH_40 PF14493.6 AJA92494.1 - 0.0082 16.6 0.3 0.034 14.6 0.2 2.0 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AJA92494.1 - 0.01 15.8 0.1 0.022 14.7 0.1 1.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 AJA92494.1 - 0.013 15.2 0.0 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain PAX PF00292.18 AJA92494.1 - 0.022 14.7 0.1 0.04 13.8 0.1 1.6 1 1 0 1 1 1 0 'Paired box' domain FaeA PF04703.12 AJA92494.1 - 0.033 14.5 0.1 0.31 11.4 0.0 2.1 2 0 0 2 2 2 0 FaeA-like protein HTH_38 PF13936.6 AJA92494.1 - 0.036 13.8 0.5 0.12 12.1 0.1 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain Ribosomal_S25 PF03297.15 AJA92494.1 - 0.089 13.0 3.0 0.15 12.3 2.8 1.4 1 1 0 1 1 1 0 S25 ribosomal protein LexA_DNA_bind PF01726.16 AJA92494.1 - 0.094 12.5 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 LexA DNA binding domain HxlR PF01638.17 AJA92494.1 - 0.098 12.5 1.3 0.76 9.7 0.2 2.4 1 1 2 3 3 3 0 HxlR-like helix-turn-helix Fe_dep_repress PF01325.19 AJA92494.1 - 0.17 12.1 0.6 0.76 10.0 0.0 2.3 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain tRNA-synt_2d PF01409.20 AJA92495.1 - 1.9e-86 289.5 0.1 4.2e-86 288.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 AJA92495.1 - 2.9e-08 33.4 0.0 1.3e-06 28.1 0.0 2.8 2 1 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain HTH_24 PF13412.6 AJA92495.1 - 0.00014 21.3 0.2 0.0015 18.1 0.1 2.6 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding PheRS_DBD3 PF18553.1 AJA92495.1 - 0.00031 21.0 2.0 0.00064 20.0 0.3 2.5 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA-synt_2b PF00587.25 AJA92495.1 - 0.003 17.5 0.3 0.015 15.3 0.1 2.0 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 AJA92495.1 - 0.0062 15.7 0.0 0.022 13.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) HTH_9 PF08221.11 AJA92495.1 - 0.025 14.7 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain ABC2_membrane_3 PF12698.7 AJA92495.1 - 0.041 13.0 0.2 0.098 11.7 0.1 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein CBM_2 PF00553.19 AJA92495.1 - 0.18 12.1 0.8 0.44 10.9 0.2 1.9 2 0 0 2 2 2 0 Cellulose binding domain DUF1410 PF07198.11 AJA92496.1 - 0.028 14.9 0.2 0.028 14.9 0.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1410) CE2_N PF17996.1 AJA92496.1 - 0.041 13.9 0.0 0.4 10.7 0.0 2.2 2 1 0 2 2 2 0 Carbohydrate esterase 2 N-terminal DUF5640 PF18692.1 AJA92496.1 - 2.6 8.1 6.5 1.4 9.0 0.2 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5640) Diphthamide_syn PF01866.17 AJA92498.1 - 1.1e-62 212.3 0.0 1.2e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Archease PF01951.16 AJA92499.1 - 3.4e-30 105.1 1.6 3.7e-30 105.0 1.6 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) VitK2_biosynth PF02621.14 AJA92501.1 - 7.1e-77 258.5 0.0 8e-77 258.3 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis Imm26 PF15428.6 AJA92501.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 26 Prefoldin_2 PF01920.20 AJA92502.1 - 1.4e-19 70.0 24.0 1.7e-19 69.7 24.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit KIP1 PF07765.12 AJA92502.1 - 1.7 8.8 13.1 0.58 10.3 1.5 2.7 1 1 2 3 3 3 0 KIP1-like protein DUF1221 PF06760.11 AJA92502.1 - 2.1 7.8 9.3 0.34 10.4 4.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1221) DUF4809 PF16067.5 AJA92502.1 - 2.3 8.4 9.4 2.2 8.5 2.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4809) AAA_23 PF13476.6 AJA92502.1 - 2.3 8.7 17.0 3.2 8.2 17.0 1.2 1 0 0 1 1 1 0 AAA domain DIX PF00778.17 AJA92503.1 - 0.073 12.9 0.0 0.21 11.4 0.0 1.8 1 1 0 1 1 1 0 DIX domain GBS_Bsp-like PF08481.10 AJA92503.1 - 0.09 12.9 0.2 15 5.8 0.0 2.2 2 0 0 2 2 2 0 GBS Bsp-like repeat Ribosomal_L3 PF00297.22 AJA92504.1 - 1.8e-73 247.6 5.1 6.2e-73 245.9 5.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L3 OB_aCoA_assoc PF01796.17 AJA92505.1 - 5.4e-13 48.7 0.4 8.2e-13 48.1 0.4 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 AJA92505.1 - 6.2e-05 22.8 0.1 9.7e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 AJA92505.1 - 0.0074 16.0 1.5 0.012 15.3 1.5 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AJA92505.1 - 0.02 14.9 0.4 0.03 14.4 0.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 AJA92505.1 - 0.027 15.2 0.3 0.036 14.8 0.3 1.2 1 0 0 1 1 1 0 zinc-ribbon family TackOD1 PF18551.1 AJA92505.1 - 0.048 13.3 0.1 0.06 13.0 0.1 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 PHF5 PF03660.14 AJA92505.1 - 0.062 13.5 0.2 0.08 13.2 0.2 1.2 1 0 0 1 1 1 0 PHF5-like protein zinc_ribbon_5 PF13719.6 AJA92505.1 - 0.095 12.5 0.7 1 9.1 0.2 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-IS66 PF13005.7 AJA92505.1 - 0.14 12.6 0.7 5.3 7.5 0.0 2.3 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-ribbon_3 PF13248.6 AJA92505.1 - 0.16 11.4 3.8 7.4 6.1 0.4 2.1 1 1 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 AJA92505.1 - 0.19 11.8 4.0 0.32 11.1 0.1 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF1802 PF08819.11 AJA92506.1 - 1.4e-44 152.0 0.3 1.6e-44 151.8 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1802) PIN_6 PF17146.4 AJA92507.1 - 8.9e-15 55.0 0.2 1.6e-14 54.1 0.2 1.3 1 0 0 1 1 1 1 PIN domain of ribonuclease PIN PF01850.21 AJA92507.1 - 6.4e-05 23.5 0.2 9.8e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 PIN domain RecR PF02132.15 AJA92507.1 - 0.00091 18.7 0.2 0.0019 17.7 0.2 1.5 1 0 0 1 1 1 1 RecR protein PIN_5 PF08745.11 AJA92507.1 - 0.00093 18.7 0.7 0.02 14.3 0.1 2.1 1 1 1 2 2 2 1 PINc domain ribonuclease zinc-ribbons_6 PF07191.12 AJA92507.1 - 0.0012 18.8 0.1 0.0023 17.9 0.1 1.4 1 0 0 1 1 1 1 zinc-ribbons zinc_ribbon_11 PF11682.8 AJA92507.1 - 0.0024 17.9 0.9 0.022 14.7 0.7 2.0 1 1 1 2 2 2 1 Probable zinc-ribbon PIN_2 PF10130.9 AJA92507.1 - 0.0094 16.2 1.1 0.016 15.4 1.1 1.5 1 1 0 1 1 1 1 PIN domain DUF4411 PF14367.6 AJA92507.1 - 0.0095 15.9 0.9 0.016 15.2 0.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4411) zf-C3HC4_3 PF13920.6 AJA92507.1 - 0.018 14.9 0.9 0.029 14.2 0.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3134 PF11332.8 AJA92507.1 - 0.041 14.2 0.1 0.069 13.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3134) DZR PF12773.7 AJA92507.1 - 0.056 13.5 0.6 0.097 12.7 0.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon NOB1_Zn_bind PF08772.11 AJA92507.1 - 0.096 12.9 1.9 0.18 12.0 1.9 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-C3HC4_2 PF13923.6 AJA92507.1 - 0.097 12.5 2.4 0.21 11.4 2.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 AJA92507.1 - 0.1 12.7 2.1 0.3 11.2 2.1 1.8 1 1 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 AJA92507.1 - 0.11 12.5 3.1 0.26 11.3 3.1 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 AJA92507.1 - 0.13 11.8 5.4 1.7 8.1 5.4 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Prok-RING_1 PF14446.6 AJA92507.1 - 0.15 12.0 2.9 0.77 9.7 2.9 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C2H2_4 PF13894.6 AJA92507.1 - 0.23 12.4 3.6 3.2 8.8 0.3 2.6 1 1 1 2 2 2 0 C2H2-type zinc finger zf-RING_5 PF14634.6 AJA92507.1 - 0.25 11.3 2.5 0.48 10.4 2.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C2H2_6 PF13912.6 AJA92507.1 - 0.56 10.3 4.7 1.4 9.0 1.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 AJA92507.1 - 0.78 9.8 3.5 72 3.5 3.5 2.4 1 1 0 1 1 1 0 BED zinc finger zf-C2H2 PF00096.26 AJA92507.1 - 1 10.0 3.4 5 7.8 0.3 2.5 1 1 1 2 2 2 0 Zinc finger, C2H2 type Zn-C2H2_12 PF18112.1 AJA92507.1 - 1.2 9.6 6.0 2.5 8.7 1.0 2.3 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_2 PF13240.6 AJA92507.1 - 1.5 8.7 5.2 39 4.1 5.1 2.3 1 1 0 1 1 1 0 zinc-ribbon domain zf-C2H2_jaz PF12171.8 AJA92507.1 - 2.1 8.7 4.5 1.1 9.6 1.9 1.9 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Radical_SAM PF04055.21 AJA92509.1 - 1.6e-17 64.4 0.0 4.8e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily MATalpha_HMGbox PF04769.12 AJA92509.1 - 0.092 12.0 0.0 0.52 9.6 0.0 2.1 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 HMG-box 5-FTHF_cyc-lig PF01812.20 AJA92510.1 - 3.1e-39 134.8 0.0 3.5e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Sulfotransfer_2 PF03567.14 AJA92510.1 - 0.14 12.0 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family Haem_oxygenas_2 PF14518.6 AJA92511.1 - 6.1e-16 58.7 0.0 7.1e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing redox enzyme TENA_THI-4 PF03070.16 AJA92511.1 - 1.7e-15 57.4 0.1 2e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Gly_radical PF01228.21 AJA92511.1 - 0.14 12.7 0.1 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 Glycine radical NDK PF00334.19 AJA92512.1 - 4.4e-53 178.9 0.0 4.9e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase GtrA PF04138.14 AJA92513.1 - 9.1e-25 87.2 13.0 1e-24 87.0 13.0 1.0 1 0 0 1 1 1 1 GtrA-like protein DUF2715 PF10895.8 AJA92513.1 - 0.01 15.5 8.0 0.44 10.1 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2715) MqsR_toxin PF15723.5 AJA92513.1 - 0.026 14.9 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA AMP-binding PF00501.28 AJA92514.1 - 2.8e-94 316.1 0.0 3.4e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AJA92514.1 - 8.3e-25 87.6 0.0 1.8e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AJA92514.1 - 4e-15 55.5 4.4 1.1e-14 54.1 4.4 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF3201 PF11447.8 AJA92514.1 - 0.067 12.7 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) Cyclophil_like PF04126.13 AJA92515.1 - 5e-10 39.2 0.0 6.1e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 AJA92515.1 - 1.3e-06 28.3 0.0 2e-06 27.7 0.0 1.2 1 1 0 1 1 1 1 Cyclophilin-like family Ubie_methyltran PF01209.18 AJA92516.1 - 1.8e-21 76.6 0.0 2.1e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 AJA92516.1 - 4e-12 46.6 0.0 5.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJA92516.1 - 1.2e-11 45.2 0.0 1.7e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJA92516.1 - 2.4e-06 27.4 0.1 6e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJA92516.1 - 0.00016 21.6 0.0 0.00018 21.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJA92516.1 - 0.00057 20.6 0.0 0.0009 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 AJA92516.1 - 0.022 14.6 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase CMAS PF02353.20 AJA92516.1 - 0.043 13.1 0.0 0.07 12.4 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ribosomal_S4e PF00900.20 AJA92517.1 - 1.1e-15 57.3 1.6 3.1e-15 55.8 0.5 2.2 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.12 AJA92517.1 - 9.6e-08 32.0 0.6 1.8e-07 31.1 0.6 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 AJA92517.1 - 0.0019 17.9 0.1 0.0039 16.9 0.1 1.6 1 0 0 1 1 1 1 S4 domain CDC48_N PF02359.18 AJA92517.1 - 0.074 13.2 0.2 6.9 6.9 0.0 3.0 1 1 2 3 3 3 0 Cell division protein 48 (CDC48), N-terminal domain zf-BED PF02892.15 AJA92518.1 - 0.062 13.3 0.4 0.085 12.9 0.4 1.3 1 0 0 1 1 1 0 BED zinc finger dsDNA_bind PF01984.20 AJA92519.1 - 7.6e-06 26.2 0.1 9.3e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.9 AJA92519.1 - 0.041 14.3 2.6 0.079 13.4 2.6 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Pterin_bind PF00809.22 AJA92520.1 - 1e-47 162.9 0.0 2.1e-47 161.9 0.0 1.5 1 1 0 1 1 1 1 Pterin binding enzyme Med28 PF11594.8 AJA92520.1 - 0.09 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 28 DnaJ PF00226.31 AJA92521.1 - 5.1e-21 74.6 6.9 6.2e-21 74.3 5.6 1.9 2 0 0 2 2 2 1 DnaJ domain FtsX PF02687.21 AJA92521.1 - 0.44 11.0 2.8 0.23 12.0 0.4 1.7 2 0 0 2 2 2 0 FtsX-like permease family YMF19 PF02326.15 AJA92521.1 - 3.4 8.5 6.6 8.3 7.3 0.2 2.7 2 1 1 3 3 3 0 Plant ATP synthase F0 zinc_ribbon_6 PF14599.6 AJA92522.1 - 0.0071 16.3 17.6 1.7 8.7 0.5 4.0 2 2 2 4 4 4 4 Zinc-ribbon Molybdop_Fe4S4 PF04879.16 AJA92522.1 - 0.016 15.2 8.1 0.11 12.5 1.3 2.3 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain SCIFF PF13165.6 AJA92522.1 - 0.06 13.3 5.2 1.2 9.2 0.3 2.5 2 0 0 2 2 2 0 Six-cysteine peptide SCIFF LIM PF00412.22 AJA92522.1 - 9.8 6.5 15.4 10 6.5 3.4 2.4 2 0 0 2 2 2 0 LIM domain HTH_23 PF13384.6 AJA92524.1 - 0.0021 17.8 0.0 0.0048 16.7 0.0 1.8 1 1 0 1 1 1 1 Homeodomain-like domain TrmB PF01978.19 AJA92524.1 - 0.018 14.9 0.1 0.64 10.0 0.0 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB GntR PF00392.21 AJA92524.1 - 0.048 13.3 0.1 0.14 11.8 0.1 1.9 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_IclR PF09339.10 AJA92524.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain TPP_enzyme_N PF02776.18 AJA92525.1 - 4.7e-59 198.8 0.1 4.2e-58 195.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 AJA92525.1 - 1.4e-48 164.1 0.0 3.1e-48 163.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 AJA92525.1 - 2.9e-44 150.5 0.6 6.3e-44 149.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M_2 PF16582.5 AJA92525.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 1 0 1 1 1 0 Middle domain of thiamine pyrophosphate Putative_PNPOx PF01243.20 AJA92526.1 - 3.2e-15 56.1 0.0 4.3e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 AJA92526.1 - 0.01 15.8 0.0 0.013 15.5 0.0 1.3 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase ACPS PF01648.20 AJA92527.1 - 3.2e-16 59.5 1.5 3.8e-16 59.2 1.5 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 AJA92527.1 - 0.11 12.6 0.0 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain MTHFR PF02219.17 AJA92528.1 - 5.1e-08 32.6 0.0 4.1e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase RFX5_N PF18326.1 AJA92528.1 - 0.34 10.7 1.4 24 4.8 0.1 2.7 2 1 1 3 3 3 0 RFX5 N-terminal domain Aminotran_3 PF00202.21 AJA92529.1 - 2.1e-54 184.7 0.1 3.1e-54 184.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-III RL10P_insert PF17777.1 AJA92530.1 - 1.1e-18 66.9 0.0 2.8e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 AJA92530.1 - 1.7e-18 66.6 2.2 2.7e-18 65.9 0.9 2.0 2 1 1 3 3 3 1 Ribosomal protein L10 CbtB PF09489.10 AJA92531.1 - 1.8e-13 50.3 2.1 2.6e-13 49.9 2.1 1.3 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) SecE PF00584.20 AJA92531.1 - 0.014 15.3 1.9 0.02 14.8 1.9 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Methyltransf_31 PF13847.6 AJA92534.1 - 3.1e-22 79.0 0.2 5e-22 78.3 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJA92534.1 - 1.1e-20 74.1 0.0 1.8e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AJA92534.1 - 1.9e-20 73.2 0.8 1.9e-19 70.0 0.8 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 AJA92534.1 - 6.7e-19 68.3 0.0 1.2e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJA92534.1 - 1.2e-13 51.3 0.0 1.8e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJA92534.1 - 1.7e-12 47.9 0.0 3.3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AJA92534.1 - 1.7e-07 31.0 0.1 3.7e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 AJA92534.1 - 3.2e-06 26.9 0.0 4.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Fibrillarin PF01269.17 AJA92534.1 - 1e-05 24.8 0.0 1.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin CheR PF01739.18 AJA92534.1 - 1.3e-05 24.8 0.7 0.0061 16.1 0.1 2.6 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain PCMT PF01135.19 AJA92534.1 - 1.8e-05 24.6 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AJA92534.1 - 6.5e-05 22.1 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.20 AJA92534.1 - 0.00024 20.5 0.1 0.00031 20.1 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 AJA92534.1 - 0.00078 19.6 0.0 0.0014 18.8 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase DREV PF05219.12 AJA92534.1 - 0.0008 18.6 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase N6_N4_Mtase PF01555.18 AJA92534.1 - 0.0027 17.5 2.5 0.34 10.6 1.2 2.3 2 1 0 2 2 2 1 DNA methylase Methyltr_RsmB-F PF01189.17 AJA92534.1 - 0.0043 16.7 0.1 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_32 PF13679.6 AJA92534.1 - 0.0045 17.0 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain GidB PF02527.15 AJA92534.1 - 0.0068 15.7 0.1 0.019 14.3 0.1 1.8 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G Rsm22 PF09243.10 AJA92534.1 - 0.0099 15.2 0.0 0.027 13.7 0.0 1.6 1 1 1 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_3 PF01596.17 AJA92534.1 - 0.015 14.5 0.1 0.027 13.6 0.1 1.4 1 0 0 1 1 1 0 O-methyltransferase MetW PF07021.12 AJA92534.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 AJA92534.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SieB PF14163.6 AJA92534.1 - 0.022 14.2 0.3 0.077 12.5 0.1 2.0 2 0 0 2 2 2 0 Super-infection exclusion protein B GCD14 PF08704.10 AJA92534.1 - 0.055 13.1 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_2 PF00891.18 AJA92534.1 - 0.056 12.7 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain UPF0020 PF01170.18 AJA92534.1 - 0.11 12.1 0.1 6.1 6.5 0.1 2.8 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 ADH_zinc_N PF00107.26 AJA92534.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Rhodanese PF00581.20 AJA92535.1 - 6.3e-12 46.0 0.1 9.1e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF4147 PF13660.6 AJA92536.1 - 3.2e-62 210.1 0.0 4.9e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 AJA92536.1 - 7.9e-30 103.3 0.0 1.9e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 MOFRL family DUF3530 PF12048.8 AJA92536.1 - 0.19 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Peptidase_S8 PF00082.22 AJA92537.1 - 5.6e-39 134.2 0.0 1.2e-38 133.1 0.0 1.5 1 1 0 1 1 1 1 Subtilase family Big_3_3 PF13750.6 AJA92537.1 - 3.7e-06 26.7 3.0 0.046 13.4 0.2 3.6 4 0 0 4 4 4 2 Bacterial Ig-like domain (group 3) DUF916 PF06030.12 AJA92537.1 - 0.00014 21.9 0.3 0.07 13.2 0.1 3.2 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF916) fn3_5 PF06280.12 AJA92537.1 - 0.00024 21.8 2.6 0.00053 20.7 0.1 2.8 3 0 0 3 3 3 1 Fn3-like domain PurS PF02700.14 AJA92538.1 - 2.1e-15 56.6 0.2 2.4e-15 56.5 0.2 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase MMR_HSR1_C PF08438.10 AJA92539.1 - 1e-30 106.6 0.5 2.3e-30 105.4 0.5 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 AJA92539.1 - 5.5e-20 71.6 0.0 5.9e-19 68.2 0.0 2.5 2 1 1 3 3 3 1 50S ribosome-binding GTPase TGS PF02824.21 AJA92539.1 - 4e-13 49.2 0.1 9.8e-13 47.9 0.1 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 AJA92539.1 - 2.7e-06 27.0 0.3 1.2e-05 24.9 0.1 2.2 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AJA92539.1 - 0.0072 16.3 0.8 0.057 13.3 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase YchF-GTPase_C PF06071.13 AJA92539.1 - 0.014 15.5 0.2 0.052 13.8 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF933) Fe-ADH PF00465.19 AJA92540.1 - 5.5e-48 163.6 0.0 1.1e-47 162.7 0.0 1.4 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AJA92540.1 - 2.6e-17 63.4 0.0 3.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 AJA92540.1 - 3.3e-06 26.5 0.0 0.0037 16.5 0.0 2.2 2 0 0 2 2 2 2 3-dehydroquinate synthase PFK PF00365.20 AJA92540.1 - 0.0015 17.9 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphofructokinase DUF202 PF02656.15 AJA92541.1 - 0.16 12.5 14.6 0.82 10.2 1.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Phage_holin_3_6 PF07332.11 AJA92541.1 - 8.5 6.4 12.5 1.2 9.2 2.5 2.5 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1272 PF06906.11 AJA92542.1 - 0.17 12.0 10.0 0.044 13.9 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 AJA92542.1 - 0.23 11.5 11.2 1.9 8.6 11.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF2318 PF10080.9 AJA92542.1 - 1.6 8.9 8.4 3.9 7.6 8.4 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) DHODB_Fe-S_bind PF10418.9 AJA92542.1 - 1.8 8.4 6.9 0.44 10.4 1.5 2.4 2 1 1 3 3 3 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B ADK_lid PF05191.14 AJA92542.1 - 2.5 8.1 6.8 3.2 7.8 2.2 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid UPF0086 PF01868.16 AJA92543.1 - 1.2e-13 50.8 0.3 1.7e-13 50.3 0.3 1.3 1 1 0 1 1 1 1 Domain of unknown function UPF0086 Pur_DNA_glyco PF02245.16 AJA92544.1 - 1.8e-57 193.6 0.0 2.1e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) PheRS_DBD3 PF18553.1 AJA92544.1 - 0.0046 17.2 1.2 0.012 15.9 0.4 2.1 2 1 1 3 3 3 1 PheRS DNA binding domain 3 Phage_cap_E PF03864.15 AJA92544.1 - 0.049 12.8 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 Phage major capsid protein E SWIRM-assoc_3 PF16498.5 AJA92545.1 - 0.056 13.7 0.0 0.067 13.4 0.0 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal CBS PF00571.28 AJA92546.1 - 3.7e-14 52.9 0.2 4e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 CBS domain HTH_3 PF01381.22 AJA92546.1 - 2e-13 50.2 0.2 3.3e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AJA92546.1 - 1.7e-07 31.2 0.4 3.5e-07 30.1 0.2 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 AJA92546.1 - 1.8e-06 28.2 0.0 2.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AJA92546.1 - 0.0035 17.3 0.0 0.0084 16.1 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_25 PF13413.6 AJA92546.1 - 0.01 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 AJA92546.1 - 0.02 15.0 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Sigma70_r4 PF04545.16 AJA92546.1 - 0.045 13.3 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 LacI PF00356.21 AJA92546.1 - 0.11 12.3 0.1 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Pou PF00157.17 AJA92546.1 - 0.14 12.1 0.1 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain TMEM171 PF15471.6 AJA92547.1 - 0.044 12.8 1.6 0.49 9.3 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF202 PF02656.15 AJA92547.1 - 0.12 12.9 1.9 0.84 10.1 3.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Acetyltransf_1 PF00583.25 AJA92548.1 - 5.8e-11 42.7 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 AJA92548.1 - 0.00044 19.9 2.0 0.00064 19.4 0.1 2.0 2 0 0 2 2 2 1 GNAT acetyltransferase FR47 PF08445.10 AJA92548.1 - 0.00058 19.8 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 AJA92548.1 - 0.00071 19.7 0.7 0.0019 18.3 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AJA92548.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AJA92548.1 - 0.0047 17.3 0.0 0.0082 16.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AJA92548.1 - 0.0048 17.0 0.0 0.042 13.9 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AJA92548.1 - 0.031 14.9 0.0 0.063 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_tran_28_C PF04101.16 AJA92549.1 - 2.6e-14 53.5 0.0 6.9e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 AJA92549.1 - 3.7e-07 29.7 0.0 0.0079 15.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 CCDC117 PF15810.5 AJA92549.1 - 0.096 13.0 0.2 0.2 12.0 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 Glyco_trans_1_4 PF13692.6 AJA92549.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Pro_isomerase PF00160.21 AJA92550.1 - 4.5e-46 157.0 0.1 7.4e-46 156.3 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Snf7 PF03357.21 AJA92551.1 - 0.017 14.7 3.3 0.079 12.6 3.3 1.8 1 1 0 1 1 1 0 Snf7 DoxX PF07681.12 AJA92552.1 - 3.5e-13 49.9 7.6 3.5e-13 49.9 7.6 1.6 1 1 1 2 2 2 2 DoxX DoxD PF04173.13 AJA92552.1 - 4.8e-07 29.8 0.9 4.8e-07 29.8 0.9 1.5 2 0 0 2 2 2 1 TQO small subunit DoxD DoxX_2 PF13564.6 AJA92552.1 - 0.0038 17.3 5.5 0.0054 16.8 5.5 1.3 1 1 0 1 1 1 1 DoxX-like family GATase PF00117.28 AJA92553.1 - 8.8e-24 84.3 0.0 9.9e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJA92553.1 - 3.5e-06 26.9 0.0 5.6e-05 23.0 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AJA92553.1 - 4.3e-05 23.5 0.0 0.00023 21.1 0.0 1.9 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 AJA92553.1 - 0.005 16.5 0.0 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ParA PF10609.9 AJA92554.1 - 2.4e-99 331.8 0.2 3.1e-99 331.4 0.2 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 AJA92554.1 - 8.4e-18 64.3 0.7 3.6e-17 62.3 0.1 2.4 2 1 0 2 2 2 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 AJA92554.1 - 1.3e-13 51.1 0.0 8.9e-13 48.4 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AJA92554.1 - 4.5e-09 36.5 2.4 1.4e-07 31.6 2.4 2.2 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 AJA92554.1 - 2.8e-07 30.1 0.0 4.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 AJA92554.1 - 7.6e-07 29.1 0.8 0.0077 16.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain Fer4_NifH PF00142.18 AJA92554.1 - 5e-06 26.2 0.1 0.00079 19.0 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AJA92554.1 - 1.4e-05 24.5 1.7 3.4e-05 23.2 0.8 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 AJA92554.1 - 0.0033 16.8 0.4 0.008 15.5 0.2 1.7 1 1 0 1 1 1 1 VirC1 protein FTHFS PF01268.19 AJA92554.1 - 0.0036 15.6 0.0 0.0051 15.1 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase CBP_BcsQ PF06564.12 AJA92554.1 - 0.0045 16.5 0.2 0.016 14.7 0.2 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 AJA92554.1 - 0.013 14.5 0.2 0.021 13.8 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 AJA92554.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 AJA92554.1 - 0.017 14.7 0.7 0.037 13.6 0.7 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AJA92554.1 - 0.13 12.1 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2024 PF09630.10 AJA92555.1 - 4.6e-36 122.5 1.7 5.2e-36 122.4 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) AA_kinase PF00696.28 AJA92556.1 - 2e-48 165.1 0.3 2.9e-48 164.6 0.3 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 AJA92556.1 - 8.4e-14 51.1 1.9 1.3e-07 31.3 0.1 3.2 4 0 0 4 4 4 2 ACT domain ACT PF01842.25 AJA92556.1 - 9.4e-10 38.1 1.2 3.5e-05 23.5 0.1 3.1 3 0 0 3 3 3 2 ACT domain DUF771 PF05595.11 AJA92556.1 - 0.042 13.8 0.5 4 7.5 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF771) MMR_HSR1_C PF08438.10 AJA92557.1 - 3.4e-31 108.1 0.6 7.5e-31 107.0 0.1 1.8 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 AJA92557.1 - 5.1e-21 74.9 0.1 1.6e-19 70.0 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 AJA92557.1 - 3.6e-07 29.9 0.5 0.011 15.3 0.1 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain TGS PF02824.21 AJA92557.1 - 1.4e-06 28.3 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 AJA92557.1 - 1.6e-05 24.5 0.1 0.0003 20.4 0.2 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AJA92557.1 - 6.2e-05 23.1 1.3 0.15 12.1 0.0 3.3 1 1 2 3 3 3 2 Dynamin family YchF-GTPase_C PF06071.13 AJA92557.1 - 0.023 14.9 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF933) PduV-EutP PF10662.9 AJA92557.1 - 0.094 12.5 0.7 28 4.4 0.1 3.9 3 1 1 4 4 4 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 AJA92557.1 - 1.5 9.3 4.5 5.3 7.5 4.5 2.0 1 1 0 1 1 1 0 AAA domain Prok-JAB PF14464.6 AJA92558.1 - 2e-09 37.3 0.0 2.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RadC PF04002.15 AJA92558.1 - 0.015 15.3 0.1 0.033 14.2 0.0 1.5 2 0 0 2 2 2 0 RadC-like JAB domain S4 PF01479.25 AJA92559.1 - 5.8e-12 45.1 0.4 1.2e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 S4 domain NAD_binding_1 PF00175.21 AJA92561.1 - 1.2e-12 48.4 0.0 2.5e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AJA92561.1 - 2.4e-08 34.2 0.0 3.5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AJA92561.1 - 0.092 12.9 0.1 0.36 11.0 0.1 1.8 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Methyltransf_34 PF11312.8 AJA92561.1 - 0.095 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase F420_oxidored PF03807.17 AJA92562.1 - 4.5e-17 62.4 0.0 7.7e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 AJA92562.1 - 0.00057 20.3 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AJA92562.1 - 0.004 17.2 0.2 0.0065 16.5 0.2 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DapB_N PF01113.20 AJA92562.1 - 0.024 14.8 0.2 0.078 13.1 0.1 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ApbA PF02558.16 AJA92562.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PDH PF02153.17 AJA92562.1 - 0.027 13.5 0.2 0.047 12.7 0.2 1.6 1 1 0 1 1 1 0 Prephenate dehydrogenase ABC_tran PF00005.27 AJA92563.1 - 1.2e-33 116.5 0.2 2e-33 115.8 0.2 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AJA92563.1 - 5.6e-07 29.2 1.3 2e-06 27.4 1.3 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AJA92563.1 - 1.3e-05 24.8 0.2 2.9e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AJA92563.1 - 4.4e-05 23.9 0.1 5.9e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AJA92563.1 - 0.00012 22.0 0.8 0.00022 21.2 0.2 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 AJA92563.1 - 0.00034 20.4 0.1 0.0035 17.1 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 AJA92563.1 - 0.0018 17.9 0.1 0.081 12.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AJA92563.1 - 0.0028 18.2 0.1 0.0069 16.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 AJA92563.1 - 0.0033 16.8 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 KaiC G-alpha PF00503.20 AJA92563.1 - 0.0034 16.6 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_30 PF13604.6 AJA92563.1 - 0.005 16.6 0.4 0.2 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 AJA92563.1 - 0.0064 16.6 1.4 0.012 15.7 1.4 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 AJA92563.1 - 0.007 15.5 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 AJA92563.1 - 0.011 16.0 0.3 0.017 15.4 0.3 1.7 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AJA92563.1 - 0.014 14.8 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 AJA92563.1 - 0.014 14.6 0.2 0.045 13.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_21 PF13304.6 AJA92563.1 - 0.018 14.9 1.5 0.15 11.8 1.3 2.0 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 AJA92563.1 - 0.029 13.2 0.5 0.11 11.2 0.0 2.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class cobW PF02492.19 AJA92563.1 - 0.049 13.2 2.1 0.098 12.2 0.4 2.1 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Thioredox_DsbH PF03190.15 AJA92563.1 - 0.052 13.5 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 APS_kinase PF01583.20 AJA92563.1 - 0.053 13.4 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 AJA92563.1 - 0.074 13.2 0.8 0.14 12.3 0.8 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AJA92563.1 - 0.086 12.7 0.5 0.21 11.5 0.2 1.8 1 1 1 2 2 2 0 NACHT domain Dynamin_N PF00350.23 AJA92563.1 - 0.32 11.0 4.3 1.7 8.7 4.3 2.1 1 1 0 1 1 1 0 Dynamin family eRF1_2 PF03464.15 AJA92564.1 - 3e-30 105.2 0.0 6.2e-29 101.0 0.0 2.4 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.15 AJA92564.1 - 1.6e-17 64.0 3.7 3.7e-17 62.8 1.1 2.5 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 AJA92564.1 - 5.5e-11 42.6 0.1 1.9e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 1 acVLRF1 PF18859.1 AJA92564.1 - 5.1e-08 33.3 0.0 1.2e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 AJA92564.1 - 5.6e-07 29.9 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Ribosomal_L7Ae PF01248.26 AJA92564.1 - 0.0053 16.5 0.1 0.014 15.1 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Phage_integr_3 PF16795.5 AJA92564.1 - 0.06 13.2 1.3 6.6 6.6 0.1 2.5 2 1 0 2 2 2 0 Archaeal phage integrase zf-3CxxC PF13695.6 AJA92564.1 - 1.4 9.5 5.7 51 4.4 3.8 3.0 1 1 1 2 2 2 0 Zinc-binding domain DUF2341 PF10102.9 AJA92565.1 - 5.9e-09 36.4 0.3 2e-08 34.7 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2341) Ribosomal_L2_C PF03947.18 AJA92567.1 - 4.7e-34 117.3 2.2 8.3e-34 116.5 2.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AJA92567.1 - 4e-06 26.7 0.0 1.3e-05 25.0 0.0 2.0 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain NIL PF09383.10 AJA92567.1 - 0.15 11.9 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 NIL domain Pyr_redox_2 PF07992.14 AJA92568.1 - 9.2e-55 185.9 1.9 1.1e-54 185.7 1.9 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AJA92568.1 - 1.3e-24 87.0 6.6 2.1e-21 76.5 1.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJA92568.1 - 1e-19 70.8 1.3 2.2e-18 66.6 0.1 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AJA92568.1 - 1.2e-05 24.6 2.5 0.00028 20.1 0.1 3.1 2 1 2 4 4 4 1 FAD binding domain Thi4 PF01946.17 AJA92568.1 - 3e-05 23.4 0.1 0.01 15.1 0.1 2.7 2 1 0 2 2 2 2 Thi4 family K_oxygenase PF13434.6 AJA92568.1 - 5.4e-05 22.5 0.3 0.17 11.0 0.0 3.2 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 AJA92568.1 - 0.00036 19.7 7.8 0.012 14.7 0.0 4.2 3 1 1 5 5 5 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 AJA92568.1 - 0.00043 19.8 2.2 0.0073 15.7 0.2 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AJA92568.1 - 0.00064 19.1 0.3 0.12 11.6 0.1 2.9 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.24 AJA92568.1 - 0.0015 18.2 7.8 0.11 12.0 0.0 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AJA92568.1 - 0.0017 18.4 1.9 0.58 10.1 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 AJA92568.1 - 0.0019 17.0 2.9 0.016 13.9 0.1 3.2 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_8 PF13450.6 AJA92568.1 - 0.019 15.2 0.1 0.07 13.4 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 AJA92568.1 - 0.027 14.9 0.3 0.13 12.7 0.0 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding MAF_flag10 PF01973.18 AJA92568.1 - 0.04 13.6 0.0 11 5.6 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function DUF115 Trp_halogenase PF04820.14 AJA92568.1 - 0.082 11.7 0.4 0.65 8.8 0.1 2.4 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 AJA92568.1 - 0.26 10.3 1.0 4.6 6.2 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein P-II PF00543.22 AJA92569.1 - 6.6e-12 45.9 0.4 8e-12 45.7 0.4 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Ribosomal_L5e PF17144.4 AJA92570.1 - 1.5e-15 57.5 2.4 5.1e-13 49.3 0.6 2.5 1 1 1 2 2 2 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18p PF00861.22 AJA92570.1 - 0.00069 20.0 0.4 0.001 19.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast TK PF00265.18 AJA92571.1 - 0.1 12.4 1.2 5.8 6.7 0.6 2.1 1 1 1 2 2 2 0 Thymidine kinase NPCBM_assoc PF10633.9 AJA92572.1 - 0.00088 19.5 0.1 2.1 8.6 0.0 4.1 3 2 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase FixG_C PF11614.8 AJA92572.1 - 0.0015 18.7 1.0 0.16 12.2 0.3 3.4 3 1 0 4 4 4 1 IG-like fold at C-terminal of FixG, putative oxidoreductase EPSP_synthase PF00275.20 AJA92572.1 - 0.0058 15.4 0.0 0.0092 14.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DUF11 PF01345.18 AJA92572.1 - 0.0067 16.7 2.7 2.9 8.2 0.9 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF11 CARDB PF07705.11 AJA92572.1 - 0.034 14.4 8.0 4.2 7.7 4.6 3.8 2 1 1 3 3 3 0 CARDB Sec23_BS PF08033.12 AJA92572.1 - 0.046 14.4 0.1 0.14 12.9 0.1 1.8 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain eIF-5a PF01287.20 AJA92573.1 - 3.7e-06 27.0 2.3 5.1e-06 26.5 2.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 AJA92573.1 - 0.016 15.2 0.3 0.3 11.1 0.0 2.7 3 0 0 3 3 3 0 Elongation factor P (EF-P) KOW-like domain Glycos_transf_1 PF00534.20 AJA92574.1 - 3.1e-24 85.4 0.0 8.1e-24 84.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AJA92574.1 - 3.5e-22 79.3 0.0 5.9e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AJA92574.1 - 3.7e-06 27.2 0.0 9.5e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AJA92574.1 - 0.022 14.8 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Pox_A22 PF04848.13 AJA92574.1 - 0.09 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A22 protein NAD_binding_10 PF13460.6 AJA92575.1 - 2.2e-14 53.8 0.1 3.8e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AJA92575.1 - 3.3e-13 49.7 0.1 5e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 AJA92575.1 - 8.2e-13 48.4 0.1 2.4e-12 46.9 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AJA92575.1 - 7.6e-07 28.4 0.0 1.7e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AJA92575.1 - 4e-05 23.2 0.3 7.1e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AJA92575.1 - 0.00086 18.5 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 AJA92575.1 - 0.0015 18.1 0.0 0.0035 16.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 AJA92575.1 - 0.0071 15.5 0.1 0.016 14.4 0.1 1.6 1 0 0 1 1 1 1 Male sterility protein 2-Hacid_dh_C PF02826.19 AJA92575.1 - 0.018 14.4 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AJA92575.1 - 0.045 13.9 0.1 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase PAC2 PF09754.9 AJA92575.1 - 0.056 13.4 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 PAC2 family KR PF08659.10 AJA92575.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 KR domain NRDD PF13597.6 AJA92575.1 - 0.076 11.8 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Polysacc_synt_2 PF02719.15 AJA92575.1 - 0.084 12.0 0.2 0.27 10.3 0.2 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ThiS PF02597.20 AJA92576.1 - 1.3e-08 35.3 0.2 5e-08 33.5 0.0 2.1 3 0 0 3 3 3 1 ThiS family CGI-121 PF08617.10 AJA92576.1 - 8.5e-07 29.2 4.6 1.4e-06 28.5 4.6 1.4 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Urm1 PF09138.11 AJA92576.1 - 0.017 15.5 0.2 0.077 13.4 0.2 2.3 1 1 0 1 1 1 0 Urm1 (Ubiquitin related modifier) TGS PF02824.21 AJA92576.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 TGS domain Endotoxin_C PF03944.14 AJA92576.1 - 0.24 11.8 5.6 0.056 13.8 1.9 1.8 2 0 0 2 2 2 0 delta endotoxin SIN1_PH PF16979.5 AJA92576.1 - 0.97 9.7 4.9 2.8 8.3 4.9 1.9 1 1 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PDEase_I PF00233.19 AJA92577.1 - 0.037 13.8 1.5 0.055 13.2 0.3 1.8 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase Peptidase_M24 PF00557.24 AJA92578.1 - 1.7e-58 197.8 0.0 2.4e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 AJA92578.1 - 1.8e-09 38.4 0.0 3.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DnaJ PF00226.31 AJA92579.1 - 2e-18 66.2 4.4 5.9e-18 64.8 4.4 1.8 1 0 0 1 1 1 1 DnaJ domain Fer4_13 PF13370.6 AJA92579.1 - 2.2e-09 37.7 1.9 2.2e-09 37.7 1.9 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AJA92579.1 - 1.2e-07 32.3 2.8 4.4e-07 30.6 2.8 1.9 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 AJA92579.1 - 0.0079 16.3 2.1 0.02 15.0 2.1 1.7 1 1 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4 PF00037.27 AJA92579.1 - 0.074 12.9 9.3 0.24 11.3 4.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 AJA92579.1 - 3.6 8.5 8.5 0.34 11.8 0.8 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain GatB_N PF02934.15 AJA92581.1 - 5.3e-62 209.7 0.0 7.5e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 AJA92581.1 - 1.3e-18 67.3 9.5 1.3e-18 67.3 9.5 2.5 3 0 0 3 3 3 1 GatB domain GAD PF02938.14 AJA92581.1 - 4.1e-07 30.1 0.8 2.1e-06 27.9 0.5 2.4 2 0 0 2 2 2 1 GAD domain YqeY PF09424.10 AJA92581.1 - 0.0012 18.9 4.1 0.0012 18.9 4.1 2.2 2 0 0 2 2 2 1 Yqey-like protein SurA_N PF09312.11 AJA92581.1 - 0.022 14.9 2.5 6.4 6.9 0.0 2.6 2 0 0 2 2 2 0 SurA N-terminal domain DUF5301 PF17225.3 AJA92582.1 - 0.047 14.1 0.4 0.066 13.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) FumaraseC_C PF10415.9 AJA92582.1 - 0.15 12.5 0.8 0.35 11.3 0.4 1.7 2 0 0 2 2 2 0 Fumarase C C-terminus SpoIIM PF01944.17 AJA92583.1 - 3.7e-09 36.8 11.8 4.6e-09 36.5 11.8 1.0 1 0 0 1 1 1 1 Stage II sporulation protein M EI24 PF07264.11 AJA92583.1 - 0.031 14.5 5.1 0.082 13.2 4.7 1.9 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) YpmT PF17431.2 AJA92583.1 - 0.061 13.4 0.4 3.6 7.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized YmpT-like SprT-like PF10263.9 AJA92584.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Nop PF01798.18 AJA92585.1 - 1e-63 214.9 0.1 1.5e-63 214.4 0.1 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin DUF2481 PF10654.9 AJA92585.1 - 0.053 13.5 1.8 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2481) DUF4079 PF13301.6 AJA92586.1 - 0.0045 17.2 0.5 0.011 15.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4079) NADH-u_ox-rdase PF10785.9 AJA92586.1 - 1.1 10.0 5.6 2.4 8.9 0.7 3.0 2 2 1 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Usp PF00582.26 AJA92587.1 - 1.3e-25 90.5 0.0 1.5e-25 90.4 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family AA_kinase PF00696.28 AJA92588.1 - 1e-38 133.3 3.6 1.1e-38 133.2 3.6 1.0 1 0 0 1 1 1 1 Amino acid kinase family MeaB PF03308.16 AJA92590.1 - 6.8e-70 235.1 4.8 8.2e-70 234.8 4.8 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 AJA92590.1 - 2.2e-06 27.4 0.1 6.2e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 AJA92590.1 - 4.8e-06 26.5 0.2 0.0024 17.7 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.14 AJA92590.1 - 5.4e-06 25.9 1.2 1.4e-05 24.5 1.1 1.8 1 1 0 1 1 1 1 KAP family P-loop domain RsgA_GTPase PF03193.16 AJA92590.1 - 1.8e-05 24.7 2.9 0.0015 18.5 0.1 2.7 3 0 0 3 3 2 1 RsgA GTPase AAA_22 PF13401.6 AJA92590.1 - 0.00031 21.0 0.5 0.0046 17.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain MnmE_helical PF12631.7 AJA92590.1 - 0.0013 19.0 2.8 0.0064 16.7 3.7 1.3 1 1 0 1 1 1 1 MnmE helical domain IIGP PF05049.13 AJA92590.1 - 0.0015 17.7 5.8 0.03 13.4 0.1 2.4 3 0 0 3 3 2 2 Interferon-inducible GTPase (IIGP) PRK PF00485.18 AJA92590.1 - 0.0021 17.8 0.4 0.0044 16.8 0.1 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 AJA92590.1 - 0.0029 18.0 0.4 0.013 15.9 0.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 AJA92590.1 - 0.0048 17.0 3.6 0.026 14.6 3.6 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 AJA92590.1 - 0.0049 17.4 0.7 0.016 15.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 AJA92590.1 - 0.0063 17.0 0.2 0.0063 17.0 0.2 2.2 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 AJA92590.1 - 0.013 15.5 0.8 0.05 13.5 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 AJA92590.1 - 0.015 15.0 0.3 0.034 13.9 0.3 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AJA92590.1 - 0.021 14.7 0.1 0.077 12.9 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase Virul_Fac PF10139.9 AJA92590.1 - 0.022 13.0 2.1 0.059 11.6 0.1 1.9 2 0 0 2 2 2 0 Putative bacterial virulence factor AAA_23 PF13476.6 AJA92590.1 - 0.023 15.2 13.4 0.58 10.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 AJA92590.1 - 0.025 14.7 3.2 2.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 AJA92590.1 - 0.026 14.4 0.6 0.085 12.8 0.0 2.1 2 1 0 2 2 2 0 NTPase GTP_EFTU PF00009.27 AJA92590.1 - 0.028 13.9 0.5 5.9 6.4 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_35 PF14516.6 AJA92590.1 - 0.031 13.1 2.0 0.076 11.8 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.22 AJA92590.1 - 0.043 14.2 0.4 0.24 11.8 0.0 2.4 2 1 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 AJA92590.1 - 0.057 12.9 0.1 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 AJA92590.1 - 0.061 13.1 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 AJA92590.1 - 0.063 12.5 2.3 0.07 12.3 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 AJA92590.1 - 0.064 13.0 2.3 0.14 11.9 0.0 2.4 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AJA92590.1 - 0.084 13.2 0.2 0.17 12.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain Flagellin_N PF00669.20 AJA92590.1 - 0.097 12.8 4.3 9.7 6.3 1.6 2.9 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region PPR_3 PF13812.6 AJA92590.1 - 0.31 11.1 1.6 13 5.9 0.0 3.2 3 0 0 3 3 3 0 Pentatricopeptide repeat domain DUF1053 PF06327.14 AJA92590.1 - 0.43 11.2 3.6 0.74 10.4 3.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) DUF4191 PF13829.6 AJA92591.1 - 0.19 11.1 4.3 0.19 11.0 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2207 PF09972.9 AJA92591.1 - 0.33 9.7 8.2 0.35 9.6 8.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PhoR PF11808.8 AJA92591.1 - 0.34 11.4 1.3 0.46 10.9 1.3 1.4 1 1 0 1 1 1 0 Phosphate regulon sensor protein PhoR Phage_holin_2_4 PF16082.5 AJA92591.1 - 0.52 10.1 1.8 0.61 9.8 1.8 1.2 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like SLATT_5 PF18160.1 AJA92591.1 - 0.55 9.5 3.7 0.6 9.4 3.7 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Mg-por_mtran_C PF07109.11 AJA92592.1 - 0.71 10.3 3.9 9.8 6.6 0.2 3.2 2 1 0 2 2 2 0 Magnesium-protoporphyrin IX methyltransferase C-terminus Guanylate_cyc PF00211.20 AJA92593.1 - 7.8e-13 48.4 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain UbiD PF01977.16 AJA92594.1 - 8.1e-91 304.9 0.0 9.2e-91 304.7 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Epimerase PF01370.21 AJA92595.1 - 2.8e-45 154.7 0.0 3.6e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJA92595.1 - 2e-29 103.1 0.0 4.9e-29 101.8 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AJA92595.1 - 1.6e-19 70.0 0.2 2.2e-19 69.6 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AJA92595.1 - 2.6e-06 27.4 0.0 7.1e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AJA92595.1 - 0.00056 19.1 0.1 0.0023 17.1 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AJA92595.1 - 0.00087 18.5 0.0 0.04 13.1 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.25 AJA92595.1 - 0.0016 18.0 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase VF530 PF09905.9 AJA92595.1 - 0.084 13.1 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 DNA-binding protein VF530 TP_methylase PF00590.20 AJA92597.1 - 7.3e-32 111.0 0.0 8.4e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Transglut_core2 PF13369.6 AJA92598.1 - 1e-41 142.1 0.0 1.7e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 AJA92598.1 - 9.6e-11 41.7 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 AJA92598.1 - 0.00037 20.2 0.5 0.002 17.8 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJA92598.1 - 0.00086 19.3 3.1 0.0024 17.9 0.3 2.6 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 AJA92598.1 - 0.0017 18.5 1.7 0.0055 16.8 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 AJA92598.1 - 0.0045 17.0 0.2 0.014 15.4 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 AJA92598.1 - 0.017 15.6 0.1 0.038 14.5 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat LAM_C PF12544.8 AJA92598.1 - 0.2 11.9 0.3 0.95 9.6 0.0 2.0 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Penicillinase_R PF03965.16 AJA92599.1 - 0.00082 19.7 0.0 0.0011 19.4 0.0 1.2 1 0 0 1 1 1 1 Penicillinase repressor Carboxyl_trans PF01039.22 AJA92600.1 - 2e-182 607.3 0.2 2.3e-182 607.1 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AJA92600.1 - 2.2e-06 27.4 0.1 5.5e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) Radical_SAM PF04055.21 AJA92601.1 - 9e-12 45.7 0.1 2.5e-11 44.3 0.1 1.8 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 AJA92601.1 - 3.8e-07 30.2 0.0 1.4e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 B12 binding domain DUF3791 PF12668.7 AJA92601.1 - 0.013 15.6 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) CbiX PF01903.17 AJA92602.1 - 1.1e-32 112.5 0.0 2e-15 57.0 0.0 2.1 2 0 0 2 2 2 2 CbiX CbiK PF06180.11 AJA92602.1 - 6.1e-06 25.7 0.8 8.4e-06 25.3 0.8 1.2 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Ferrochelatase PF00762.19 AJA92602.1 - 1.3e-05 24.5 0.0 0.0026 16.9 0.0 2.0 2 0 0 2 2 2 2 Ferrochelatase GTP_EFTU PF00009.27 AJA92603.1 - 1.1e-31 110.0 0.0 5.8e-31 107.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 AJA92603.1 - 1.6e-23 82.8 0.9 1.2e-21 76.8 0.3 2.6 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 AJA92603.1 - 2.6e-21 75.3 0.1 9.1e-21 73.6 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 AJA92603.1 - 5.7e-08 32.8 0.1 3.1e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AJA92603.1 - 6.2e-06 26.5 0.1 0.00028 21.2 0.0 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Roc PF08477.13 AJA92603.1 - 0.00031 20.9 0.0 0.0031 17.7 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 AJA92603.1 - 0.0006 19.9 0.2 0.057 13.5 0.1 3.0 2 0 0 2 2 2 1 Dynamin family ATP_bind_1 PF03029.17 AJA92603.1 - 0.00065 19.6 0.0 0.0028 17.5 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 AJA92603.1 - 0.0099 15.8 2.8 0.31 10.9 0.1 3.4 2 1 1 3 3 3 1 RsgA GTPase Ras PF00071.22 AJA92603.1 - 0.017 14.7 0.0 0.097 12.3 0.0 2.3 1 1 0 1 1 1 0 Ras family PhoU PF01895.19 AJA92604.1 - 4.8e-26 91.0 12.8 2.4e-19 69.6 1.0 2.3 2 0 0 2 2 2 2 PhoU domain MazE_antitoxin PF04014.18 AJA92604.1 - 8.3e-08 32.0 0.1 1.3e-06 28.2 0.0 2.8 2 1 1 3 3 3 1 Antidote-toxin recognition MazE, bacterial antitoxin DUF1905 PF08922.11 AJA92604.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) HD_4 PF13328.6 AJA92605.1 - 5.8e-16 58.6 0.1 8.9e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 HD domain HD PF01966.22 AJA92605.1 - 0.0008 19.6 0.1 0.002 18.3 0.1 1.6 1 1 0 1 1 1 1 HD domain NAD_binding_6 PF08030.12 AJA92605.1 - 0.013 15.6 1.5 0.017 15.2 1.5 1.2 1 0 0 1 1 1 0 Ferric reductase NAD binding domain ILVD_EDD PF00920.21 AJA92606.1 - 1.8e-209 696.7 4.5 2e-209 696.5 4.5 1.0 1 0 0 1 1 1 1 Dehydratase family Ribosomal_L5_C PF00673.21 AJA92607.1 - 6.6e-22 77.5 0.0 1.2e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AJA92607.1 - 1.8e-13 50.6 0.2 3.4e-13 49.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Rad51 PF08423.11 AJA92608.1 - 2.2e-90 302.4 0.1 2.7e-90 302.1 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 AJA92608.1 - 1.4e-10 41.1 0.2 2e-10 40.6 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 AJA92608.1 - 4.9e-09 35.9 0.3 9.7e-09 34.9 0.3 1.5 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 AJA92608.1 - 3.9e-05 23.3 0.0 6.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 AJA92608.1 - 0.00013 22.5 0.1 0.00045 20.8 0.1 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 AJA92608.1 - 0.016 14.9 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AJA92608.1 - 0.029 14.9 0.0 0.06 13.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_pol_RpbG PF16992.5 AJA92608.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase, subunit G AAA_22 PF13401.6 AJA92608.1 - 0.055 13.8 0.1 0.11 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain DNA_pol_lambd_f PF10391.9 AJA92608.1 - 0.07 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda RNA_helicase PF00910.22 AJA92608.1 - 0.085 13.3 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 AJA92608.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 AJA92608.1 - 0.13 12.1 0.0 0.74 9.7 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ABC2_membrane PF01061.24 AJA92609.1 - 2.4e-21 76.1 23.3 2.4e-21 76.1 23.3 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AJA92609.1 - 1.9e-14 53.6 39.2 3.9e-14 52.5 28.0 2.0 1 1 1 2 2 2 2 ABC-2 family transporter protein DUF3493 PF11998.8 AJA92609.1 - 0.21 11.8 0.0 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 ABC2_membrane_4 PF12730.7 AJA92609.1 - 0.56 10.1 17.7 0.04 13.9 10.3 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Thioredox_DsbH PF03190.15 AJA92610.1 - 1.2e-74 249.7 0.1 2.4e-74 248.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 AJA92610.1 - 3.9e-10 39.8 0.0 7.5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.13 AJA92610.1 - 2.3e-07 30.5 6.5 0.00025 20.6 0.4 3.9 3 1 1 4 4 4 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 AJA92610.1 - 8.6e-07 27.8 1.1 4.9e-05 22.0 0.3 2.8 2 1 1 3 3 3 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 AJA92610.1 - 0.00049 19.3 1.5 0.33 10.0 0.0 2.9 2 2 0 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 AJA92610.1 - 0.0051 16.4 2.0 0.016 14.8 0.5 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Thioredoxin_2 PF13098.6 AJA92610.1 - 0.0064 16.9 0.0 0.023 15.1 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin-like domain GlcNAc_2-epim PF07221.11 AJA92610.1 - 0.028 13.7 0.2 0.25 10.6 0.1 2.3 2 1 1 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Pec_lyase PF09492.10 AJA92610.1 - 0.03 13.7 1.8 0.95 8.7 0.6 2.3 2 0 0 2 2 2 0 Pectic acid lyase DAO PF01266.24 AJA92611.1 - 7.4e-37 127.7 0.0 9.6e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 AJA92611.1 - 2.8e-07 29.5 0.1 0.012 14.2 0.0 2.4 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 AJA92611.1 - 0.00044 19.6 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AJA92611.1 - 0.0013 18.0 0.0 0.0062 15.8 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Sda PF08970.10 AJA92611.1 - 0.022 14.5 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 Sporulation inhibitor A DUF5107 PF17128.4 AJA92611.1 - 0.022 13.9 1.1 0.47 9.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5107) HI0933_like PF03486.14 AJA92611.1 - 0.037 12.7 0.0 0.18 10.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein DUF1398 PF07166.11 AJA92611.1 - 0.049 13.7 0.2 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) Trp_halogenase PF04820.14 AJA92611.1 - 0.11 11.4 0.6 0.49 9.2 0.6 1.9 1 1 0 1 1 1 0 Tryptophan halogenase DUF900 PF05990.12 AJA92613.1 - 3.2e-14 53.0 0.1 4.8e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF726 PF05277.12 AJA92613.1 - 5.1e-10 38.8 0.0 7.3e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.22 AJA92613.1 - 2.5e-06 27.6 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 AJA92613.1 - 4e-06 26.8 0.1 6.4e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 AJA92613.1 - 1.6e-05 24.6 3.0 3e-05 23.6 3.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 AJA92613.1 - 6.5e-05 22.6 0.1 8.8e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_8 PF06259.12 AJA92613.1 - 0.00039 20.1 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Hydrolase_4 PF12146.8 AJA92613.1 - 0.0025 17.1 0.0 0.0032 16.8 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Lipase PF00151.19 AJA92613.1 - 0.0051 16.2 0.4 0.0069 15.7 0.1 1.4 2 0 0 2 2 2 1 Lipase DUF1749 PF08538.10 AJA92613.1 - 0.015 14.4 0.1 0.026 13.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) VirJ PF06057.11 AJA92613.1 - 0.038 13.9 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) LCAT PF02450.15 AJA92613.1 - 0.044 13.0 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 AJA92613.1 - 0.19 11.8 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF4295 PF14128.6 AJA92613.1 - 0.58 10.0 3.7 0.75 9.7 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4295) PKD PF00801.20 AJA92614.1 - 0.011 15.5 0.6 0.011 15.5 0.6 2.6 2 1 0 2 2 2 0 PKD domain ASH PF15780.5 AJA92614.1 - 0.019 15.1 0.0 0.066 13.4 0.0 1.8 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin NPAT_C PF15712.5 AJA92614.1 - 0.068 11.8 0.1 0.083 11.5 0.1 1.1 1 0 0 1 1 1 0 NPAT C terminus Carot_N PF09150.10 AJA92614.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal GHMP_kinases_N PF00288.26 AJA92615.1 - 2.8e-16 59.5 1.5 5.6e-16 58.5 1.0 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AJA92615.1 - 6.1e-12 45.7 0.0 1.8e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DUF3091 PF11291.8 AJA92615.1 - 0.028 14.6 2.1 0.028 14.6 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) DUF2666 PF10869.8 AJA92615.1 - 0.15 12.3 5.3 0.063 13.5 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) HD_3 PF13023.6 AJA92616.1 - 1.9e-36 125.5 0.3 2.1e-36 125.3 0.3 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 AJA92616.1 - 1e-15 58.0 0.3 1.3e-15 57.6 0.3 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 AJA92616.1 - 0.00023 21.4 0.0 0.00054 20.2 0.0 1.6 1 1 0 1 1 1 1 HD domain Cas_Cas4 PF01930.17 AJA92617.1 - 0.0012 19.0 0.3 0.0015 18.7 0.3 1.3 1 1 0 1 1 1 1 Domain of unknown function DUF83 AsnC_trans_reg PF01037.21 AJA92619.1 - 8.2e-07 28.9 0.4 1.1e-06 28.5 0.4 1.2 1 1 0 1 1 1 1 Lrp/AsnC ligand binding domain PepSY_TM_like_2 PF16357.5 AJA92620.1 - 0.00048 20.2 0.1 0.00074 19.6 0.1 1.3 1 0 0 1 1 1 1 Putative PepSY_TM-like Diphthami_syn_2 PF01902.17 AJA92622.1 - 3.2e-57 193.6 0.0 3.7e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Diphthamide synthase QueC PF06508.13 AJA92622.1 - 0.015 14.8 0.0 0.042 13.3 0.0 1.8 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 AJA92622.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family zinc_ribbon_15 PF17032.5 AJA92623.1 - 0.00037 21.2 1.9 0.0017 19.1 1.9 2.0 1 1 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 AJA92623.1 - 0.00066 19.7 1.3 0.00087 19.3 0.4 1.7 2 0 0 2 2 2 1 Double zinc ribbon HypA PF01155.19 AJA92623.1 - 0.031 14.3 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 AJA92623.1 - 0.16 11.7 2.6 0.23 11.2 0.9 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 AJA92623.1 - 1.8 8.1 4.9 5.3 6.6 4.9 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 AJA92623.1 - 2.4 7.9 5.7 7.3 6.3 0.2 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain TrmB PF01978.19 AJA92625.1 - 0.0026 17.6 0.0 0.0048 16.7 0.0 1.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB DUF4947 PF16305.5 AJA92625.1 - 0.037 14.0 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4947) Asp_Glu_race PF01177.22 AJA92626.1 - 2.2e-11 44.0 0.0 3.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase ToxS PF17323.2 AJA92626.1 - 0.013 15.1 0.6 0.048 13.3 0.2 1.9 2 0 0 2 2 2 0 Trans-membrane regulatory protein ToxS Lipase_GDSL PF00657.22 AJA92626.1 - 0.022 14.7 1.3 0.21 11.5 1.1 2.2 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Pyr_redox PF00070.27 AJA92626.1 - 0.12 13.0 0.5 1.8 9.1 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FTR1 PF03239.14 AJA92627.1 - 1.9e-18 66.7 19.2 2.5e-17 63.0 18.6 2.4 1 1 0 1 1 1 1 Iron permease FTR1 family Atthog PF18800.1 AJA92627.1 - 0.18 11.7 3.0 0.54 10.1 2.8 2.0 1 1 0 1 1 1 0 Attenuator of Hedgehog DUF4363 PF14276.6 AJA92627.1 - 0.31 11.2 3.6 0.6 10.2 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) DUF1211 PF06736.11 AJA92627.1 - 1.8 9.1 6.2 89 3.6 1.8 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1211) GATase PF00117.28 AJA92628.1 - 8.1e-22 77.9 0.0 9e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJA92628.1 - 3.6e-10 40.0 0.1 0.00035 20.4 0.1 2.2 1 1 1 2 2 2 2 Peptidase C26 SNO PF01174.19 AJA92628.1 - 0.0057 16.5 0.0 0.077 12.8 0.0 2.0 2 0 0 2 2 2 1 SNO glutamine amidotransferase family DUF3473 PF11959.8 AJA92629.1 - 3.1e-33 114.6 0.0 4.7e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3473) Polysacc_deac_1 PF01522.21 AJA92629.1 - 8e-12 45.1 0.0 9.4e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase DapB_N PF01113.20 AJA92630.1 - 1.7e-07 31.4 0.0 4.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.20 AJA92630.1 - 0.0028 17.2 0.2 0.034 13.8 0.1 2.6 1 1 1 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AJA92630.1 - 0.0044 17.3 0.1 0.036 14.4 0.0 2.5 2 1 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 AJA92630.1 - 0.0055 17.3 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 AJA92630.1 - 0.0092 16.4 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Spc7 PF08317.11 AJA92631.1 - 0.0027 16.6 7.5 0.0031 16.5 7.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF848 PF05852.11 AJA92631.1 - 0.065 13.4 5.9 0.071 13.2 5.9 1.0 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DASH_Spc34 PF08657.10 AJA92631.1 - 0.098 12.4 8.2 0.17 11.6 0.1 2.0 1 1 1 2 2 2 0 DASH complex subunit Spc34 BST2 PF16716.5 AJA92631.1 - 0.12 13.0 4.1 0.19 12.3 4.1 1.4 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 Fib_alpha PF08702.10 AJA92631.1 - 0.23 11.6 5.5 2.1 8.5 5.5 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 AJA92631.1 - 0.24 11.9 6.8 0.48 10.9 6.8 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 Atg14 PF10186.9 AJA92631.1 - 0.28 10.2 5.0 0.32 10.1 5.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 AJA92631.1 - 0.34 11.6 3.7 0.65 10.7 3.3 1.6 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 AJA92631.1 - 0.34 10.7 7.3 3 7.7 2.0 2.1 2 0 0 2 2 2 0 Septum formation initiator Iron_permease PF04120.12 AJA92631.1 - 0.36 10.6 3.1 0.39 10.5 3.1 1.1 1 0 0 1 1 1 0 Low affinity iron permease Prefoldin_2 PF01920.20 AJA92631.1 - 0.41 10.6 12.4 2.2 8.3 5.4 2.0 1 1 1 2 2 2 0 Prefoldin subunit GPHR_N PF12537.8 AJA92631.1 - 0.57 10.3 2.0 2 8.5 0.4 2.0 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Spc29 PF17082.5 AJA92631.1 - 0.7 9.7 4.9 0.74 9.6 4.9 1.0 1 0 0 1 1 1 0 Spindle Pole Component 29 FapA PF03961.13 AJA92631.1 - 0.83 8.2 9.2 0.86 8.1 9.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TPD52 PF04201.15 AJA92631.1 - 1.8 8.1 7.3 0.59 9.7 2.2 1.9 1 1 1 2 2 2 0 Tumour protein D52 family SecE PF00584.20 AJA92632.1 - 9e-05 22.3 0.4 9.2e-05 22.3 0.4 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Met_10 PF02475.16 AJA92634.1 - 2.4e-56 190.6 0.0 3.1e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 AJA92634.1 - 1.9e-05 24.2 0.1 2.9e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 AJA92634.1 - 9e-05 22.2 0.0 0.00019 21.1 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 AJA92634.1 - 0.00027 20.7 0.1 0.00056 19.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 AJA92634.1 - 0.00063 19.4 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRM PF02005.16 AJA92634.1 - 0.0013 18.0 0.1 0.0017 17.6 0.1 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.14 AJA92634.1 - 0.0038 16.8 0.2 0.011 15.3 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N PF00107.26 AJA92634.1 - 0.0044 17.0 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 AJA92634.1 - 0.0082 16.8 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJA92634.1 - 0.025 15.2 0.0 0.055 14.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF4717 PF15838.5 AJA92635.1 - 0.12 12.4 0.3 4.4 7.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4717) ADH_N PF08240.12 AJA92636.1 - 2e-30 104.9 0.6 3.8e-30 104.0 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AJA92636.1 - 6.3e-17 61.8 0.5 1e-16 61.1 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AJA92636.1 - 0.00035 19.9 0.6 0.00076 18.8 0.6 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 AJA92636.1 - 0.0015 17.9 0.7 0.0032 16.9 0.6 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 AJA92636.1 - 0.0033 17.2 0.1 0.0068 16.2 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 AJA92636.1 - 0.0049 17.9 0.1 0.0083 17.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 AJA92636.1 - 0.0064 16.2 0.9 0.017 14.9 0.3 1.8 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 AJA92636.1 - 0.01 16.1 0.1 0.02 15.1 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 AJA92636.1 - 0.011 16.5 0.3 0.15 12.9 0.1 2.4 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 AJA92636.1 - 0.033 13.9 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA S1-like PF14444.6 AJA92636.1 - 0.039 13.9 0.8 0.3 11.0 0.1 2.7 2 1 1 3 3 3 0 S1-like CoA_binding PF02629.19 AJA92636.1 - 0.061 14.0 5.0 0.12 13.1 2.2 2.8 2 1 0 2 2 2 0 CoA binding domain DOT1 PF08123.13 AJA92636.1 - 0.066 12.7 2.5 0.37 10.3 2.5 1.9 1 1 0 1 1 1 0 Histone methylation protein DOT1 NAD_binding_7 PF13241.6 AJA92636.1 - 0.12 12.9 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UbiA PF01040.18 AJA92637.1 - 1.5e-51 175.1 21.6 2e-51 174.7 21.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FA_desaturase PF00487.24 AJA92637.1 - 0.28 11.0 0.0 0.28 11.0 0.0 3.5 1 1 2 4 4 4 0 Fatty acid desaturase Sbt_1 PF05982.12 AJA92638.1 - 1.1e-101 340.2 23.4 1.2e-101 340.0 23.4 1.0 1 0 0 1 1 1 1 Na+-dependent bicarbonate transporter superfamily DUF1772 PF08592.11 AJA92638.1 - 0.0014 19.0 4.6 0.037 14.3 1.5 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) SMC_N PF02463.19 AJA92639.1 - 2.8e-15 56.4 25.4 3.4e-09 36.5 0.6 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AJA92639.1 - 1.8e-09 38.4 81.4 7.8e-06 26.5 62.0 4.3 1 1 1 2 2 1 1 AAA domain AAA_29 PF13555.6 AJA92639.1 - 2.5e-09 36.8 0.2 4.8e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AJA92639.1 - 2.6e-09 37.3 13.5 0.00013 21.9 1.9 3.0 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AJA92639.1 - 1.4e-08 34.8 57.4 1.3e-05 25.1 29.6 2.3 1 1 1 2 2 2 2 AAA ATPase domain AAA_27 PF13514.6 AJA92639.1 - 4e-07 29.8 0.9 4e-07 29.8 0.9 2.9 2 1 1 3 3 3 1 AAA domain SbcCD_C PF13558.6 AJA92639.1 - 1.6e-05 25.0 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 AJA92639.1 - 0.01 16.3 0.0 0.01 16.3 0.0 4.8 2 1 0 2 2 1 0 ABC transporter RsgA_GTPase PF03193.16 AJA92639.1 - 0.012 15.6 7.2 0.013 15.5 0.0 3.5 3 0 0 3 3 3 0 RsgA GTPase Snapin_Pallidin PF14712.6 AJA92639.1 - 0.017 15.5 7.2 0.017 15.5 7.2 6.2 4 2 2 6 6 4 0 Snapin/Pallidin AAA_16 PF13191.6 AJA92639.1 - 0.57 10.5 2.7 2.3 8.6 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain MukB PF04310.12 AJA92639.1 - 3.9 7.2 12.8 0.61 9.9 0.1 3.7 3 1 0 4 4 4 0 MukB N-terminal MMR_HSR1 PF01926.23 AJA92639.1 - 4.5 7.4 8.5 0.24 11.5 0.1 3.1 2 1 1 3 3 3 0 50S ribosome-binding GTPase AAA_19 PF13245.6 AJA92639.1 - 7 7.0 8.4 3.1 8.1 0.6 3.2 3 1 0 3 3 3 0 AAA domain Adenine_deam_C PF13382.6 AJA92641.1 - 1.3e-43 148.3 0.0 5.1e-43 146.3 0.0 1.9 2 0 0 2 2 2 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 AJA92641.1 - 1.5e-13 50.8 0.0 1e-12 48.0 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AJA92641.1 - 7.5e-06 25.7 1.2 0.0063 16.0 0.3 2.1 2 0 0 2 2 2 2 Amidohydrolase family DUF2099 PF09872.9 AJA92641.1 - 0.0042 16.3 2.1 0.24 10.6 0.0 3.2 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2099) IF-2B PF01008.17 AJA92641.1 - 0.044 13.0 0.1 0.094 11.9 0.1 1.5 1 0 0 1 1 1 0 Initiation factor 2 subunit family DUF1059 PF06348.11 AJA92642.1 - 1.3e-08 34.9 0.1 1.5e-08 34.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) HMG-CoA_red PF00368.18 AJA92643.1 - 5.9e-104 348.0 7.5 6.7e-104 347.8 7.5 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Lipase_GDSL PF00657.22 AJA92644.1 - 5.8e-06 26.4 0.2 1.3e-05 25.3 0.2 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 AJA92644.1 - 9.4e-06 26.1 0.0 1.5e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_42 PF02449.15 AJA92645.1 - 0.002 17.6 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase Phage_int_SAM_6 PF18644.1 AJA92645.1 - 0.073 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Phage integrase SAM-like domain Thiolase_N PF00108.23 AJA92646.1 - 1.1e-12 47.9 0.3 3.3e-11 43.1 0.3 2.3 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AJA92646.1 - 1.5e-12 47.2 0.1 2.6e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AJA92646.1 - 0.002 17.7 0.5 0.0048 16.5 0.0 1.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AJA92646.1 - 0.03 14.3 1.4 3.5 7.7 0.0 3.1 2 1 1 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain RT_RNaseH_2 PF17919.1 AJA92646.1 - 0.043 13.8 0.1 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase 3HCDH_N PF02737.18 AJA92647.1 - 3.8e-66 222.4 2.3 3.8e-66 222.4 2.3 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AJA92647.1 - 2.8e-37 127.2 0.2 8.8e-26 90.4 0.0 3.3 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 AJA92647.1 - 2.9e-06 27.5 0.1 7e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AJA92647.1 - 3.1e-06 27.2 1.2 7e-06 26.1 1.2 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 AJA92647.1 - 0.0007 20.1 0.5 0.0033 18.0 0.5 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1803 PF08820.10 AJA92647.1 - 0.0058 16.6 0.1 0.017 15.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1803) DUF4078 PF13300.6 AJA92647.1 - 0.011 16.1 0.5 0.021 15.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) UDPG_MGDP_dh_N PF03721.14 AJA92647.1 - 0.045 13.3 0.2 0.085 12.4 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 AJA92647.1 - 0.12 12.8 0.6 0.32 11.4 0.6 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain adh_short_C2 PF13561.6 AJA92647.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase AlaDh_PNT_C PF01262.21 AJA92647.1 - 0.14 11.5 0.7 0.26 10.5 0.2 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 AJA92647.1 - 0.14 11.4 0.1 0.24 10.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 AJA92647.1 - 1.2 8.7 4.5 54 3.3 4.5 2.4 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lar_restr_allev PF14354.6 AJA92648.1 - 0.24 11.8 4.1 1.9 8.9 4.1 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-CHY PF05495.12 AJA92648.1 - 2.4 8.7 10.5 0.73 10.4 4.8 2.2 2 0 0 2 2 2 0 CHY zinc finger CofC PF01983.16 AJA92649.1 - 1.2e-25 90.0 5.5 1.4e-25 89.8 5.5 1.0 1 0 0 1 1 1 1 Guanylyl transferase CofC like NTP_transf_3 PF12804.7 AJA92649.1 - 1.5e-07 31.9 0.0 1.9e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 AJA92649.1 - 0.0011 18.9 0.7 0.0017 18.3 0.7 1.3 1 0 0 1 1 1 1 Cytidylyltransferase GatB_Yqey PF02637.18 AJA92649.1 - 0.044 13.7 1.9 0.081 12.8 1.9 1.4 1 0 0 1 1 1 0 GatB domain Pantoate_transf PF02548.15 AJA92650.1 - 8e-98 327.0 1.4 9e-98 326.8 1.4 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 AJA92650.1 - 0.00022 20.8 3.1 0.016 14.7 0.3 1.8 1 1 1 2 2 2 2 Phosphoenolpyruvate phosphomutase ATP-grasp_2 PF08442.10 AJA92652.1 - 1.4e-46 158.6 0.6 2.9e-46 157.6 0.6 1.5 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 AJA92652.1 - 6.4e-17 61.8 0.5 1.7e-16 60.4 0.5 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 AJA92652.1 - 5.8e-15 55.3 0.1 1.6e-14 53.9 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AJA92652.1 - 1.2e-06 28.1 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 AJA92652.1 - 0.0003 20.4 0.0 0.00083 19.0 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain DUF4152 PF13680.6 AJA92652.1 - 0.087 12.2 0.5 0.77 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4152) Dus PF01207.17 AJA92653.1 - 5.2e-76 255.7 0.0 5.8e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.20 AJA92653.1 - 0.0058 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NanE PF04131.14 AJA92653.1 - 0.0058 15.8 0.1 0.038 13.2 0.0 2.1 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase SOR_SNZ PF01680.17 AJA92653.1 - 0.0083 15.9 0.0 0.2 11.4 0.0 2.4 1 1 1 2 2 2 1 SOR/SNZ family TMP-TENI PF02581.17 AJA92653.1 - 0.073 12.4 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase His_biosynth PF00977.21 AJA92653.1 - 0.096 12.1 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein Prefoldin PF02996.17 AJA92654.1 - 6.3e-21 74.5 4.5 6.3e-21 74.5 4.5 1.7 1 1 1 2 2 2 1 Prefoldin subunit DHR10 PF18595.1 AJA92654.1 - 0.0004 20.4 13.9 0.017 15.2 3.0 2.0 2 0 0 2 2 2 2 Designed helical repeat protein 10 domain Prefoldin_2 PF01920.20 AJA92654.1 - 0.0005 20.0 12.6 0.0052 16.7 2.7 2.1 2 0 0 2 2 2 2 Prefoldin subunit RF-1 PF00472.20 AJA92654.1 - 0.0056 16.6 1.2 0.0056 16.6 1.2 2.0 2 0 0 2 2 2 1 RF-1 domain Laminin_II PF06009.12 AJA92654.1 - 0.016 15.2 8.5 0.31 11.0 0.8 2.2 2 0 0 2 2 2 0 Laminin Domain II kleA_kleC PF17383.2 AJA92654.1 - 0.019 15.3 3.5 0.5 10.7 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A DASH_Dad2 PF08654.10 AJA92654.1 - 0.028 14.8 1.0 0.028 14.8 1.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad2 Phage_HK97_TLTM PF06120.11 AJA92654.1 - 0.036 13.3 10.8 0.045 13.0 10.8 1.0 1 0 0 1 1 1 0 Tail length tape measure protein 5_3_exonuc PF01367.20 AJA92654.1 - 0.045 14.4 3.9 0.078 13.6 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold PhoQ_Sensor PF08918.10 AJA92654.1 - 0.051 13.4 0.3 0.051 13.4 0.3 1.9 1 1 1 2 2 2 0 PhoQ Sensor DUF3848 PF12959.7 AJA92654.1 - 0.069 13.2 0.6 0.069 13.2 0.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3848) Mod_r PF07200.13 AJA92654.1 - 0.069 13.2 10.1 0.14 12.3 10.1 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein RasGAP_C PF03836.15 AJA92654.1 - 0.079 13.1 10.2 0.11 12.6 0.4 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Sec20 PF03908.13 AJA92654.1 - 0.17 11.8 9.2 2.3 8.2 3.1 2.4 2 0 0 2 2 2 0 Sec20 DEDD_Tnp_IS110 PF01548.17 AJA92654.1 - 0.45 10.4 2.9 0.42 10.5 0.3 1.9 2 0 0 2 2 2 0 Transposase WXG100 PF06013.12 AJA92654.1 - 0.46 10.7 13.1 0.75 10.1 3.4 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG SecD-TM1 PF13721.6 AJA92654.1 - 0.49 10.9 6.0 0.39 11.2 0.9 2.1 2 0 0 2 2 2 0 SecD export protein N-terminal TM region DUF1664 PF07889.12 AJA92654.1 - 0.94 9.5 10.3 0.86 9.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 AJA92654.1 - 2.3 8.6 21.2 0.63 10.4 6.3 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Flagellar_rod PF05149.12 AJA92654.1 - 2.6 7.4 12.5 0.16 11.4 3.6 2.0 2 0 0 2 2 2 0 Paraflagellar rod protein FlaC_arch PF05377.11 AJA92654.1 - 2.6 8.5 11.2 0.78 10.2 2.1 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2120 PF09893.9 AJA92654.1 - 2.7 8.1 7.2 1.5 8.9 0.9 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Seryl_tRNA_N PF02403.22 AJA92654.1 - 3 8.1 13.1 0.75 10.0 2.7 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain KIP1 PF07765.12 AJA92654.1 - 3 8.0 8.1 2 8.6 1.7 2.3 2 0 0 2 2 2 0 KIP1-like protein TRPM_tetra PF16519.5 AJA92654.1 - 3.3 7.9 8.8 0.46 10.6 2.4 2.6 2 2 0 2 2 2 0 Tetramerisation domain of TRPM SKA1 PF07160.12 AJA92654.1 - 3.3 7.5 12.8 0.64 9.8 3.6 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 PilO PF04350.13 AJA92654.1 - 4.6 7.4 12.5 0.55 10.4 5.2 2.1 2 0 0 2 2 2 0 Pilus assembly protein, PilO DUF745 PF05335.13 AJA92654.1 - 5.3 6.7 14.6 6.7 6.4 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) CLZ PF16526.5 AJA92654.1 - 6.3 7.2 11.3 5.5 7.4 2.8 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 AJA92654.1 - 6.5 5.5 16.5 1.2 7.9 5.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Med10 PF09748.9 AJA92654.1 - 7.2 6.6 10.7 1.9 8.5 1.3 2.2 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex BLOC1_2 PF10046.9 AJA92654.1 - 7.5 6.9 13.3 4.9 7.5 2.7 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 AJA92654.1 - 8.5 6.2 12.9 2.2 8.1 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Spc24 PF08286.11 AJA92654.1 - 9.5 6.5 14.2 11 6.3 2.7 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ADH_zinc_N PF00107.26 AJA92655.1 - 2.1e-25 89.2 0.0 3.4e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AJA92655.1 - 5.5e-20 71.3 0.1 8.9e-20 70.6 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 AJA92655.1 - 9.6e-19 68.7 0.1 1.5e-18 68.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AJA92655.1 - 0.037 13.3 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ACP_syn_III_C PF08541.10 AJA92655.1 - 0.27 11.4 0.8 0.73 10.0 0.4 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Sigma70_r1_1 PF03979.14 AJA92656.1 - 2.3 8.3 5.7 1.5 8.9 0.2 2.5 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 RGP PF03214.13 AJA92657.1 - 6.3e-25 88.0 0.1 8.4e-25 87.7 0.1 1.2 1 0 0 1 1 1 1 Reversibly glycosylated polypeptide TetR_C_28 PF17937.1 AJA92658.1 - 0.01 16.3 0.1 0.028 14.9 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Collagen PF01391.18 AJA92659.1 - 5.1e-43 144.7 162.7 5e-10 39.0 28.4 5.3 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) DsbD PF02683.15 AJA92660.1 - 1.6e-57 194.8 16.3 1.4e-45 155.8 10.3 2.1 2 0 0 2 2 2 2 Cytochrome C biogenesis protein transmembrane region AhpC-TSA PF00578.21 AJA92660.1 - 1.4e-10 41.1 0.0 2.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJA92660.1 - 6e-10 39.0 0.0 9.8e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin DsbD_2 PF13386.6 AJA92660.1 - 3.3e-08 33.7 15.2 1.2e-07 31.9 12.8 2.0 2 0 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin_8 PF13905.6 AJA92660.1 - 1.6e-07 31.6 0.0 3.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like SfLAP PF11139.8 AJA92660.1 - 0.0017 17.8 9.0 0.004 16.6 7.4 1.9 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein Thioredoxin PF00085.20 AJA92660.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin TMEM43 PF07787.12 AJA92660.1 - 0.55 9.6 9.4 0.17 11.3 0.2 2.9 1 1 1 3 3 3 0 Transmembrane protein 43 CPSase_L_D2 PF02786.17 AJA92661.1 - 9.1e-102 339.0 0.1 2.5e-74 249.4 0.2 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 AJA92661.1 - 2.2e-36 124.9 0.0 5.3e-36 123.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 AJA92661.1 - 1.3e-19 70.4 0.3 1.3e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AJA92661.1 - 1.8e-15 57.1 4.1 1.1e-07 31.6 0.0 2.7 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus MGS PF02142.22 AJA92661.1 - 2.7e-14 53.1 0.1 2.7e-13 49.9 0.0 2.9 3 0 0 3 3 3 1 MGS-like domain ATPgrasp_Ter PF15632.6 AJA92661.1 - 1.2e-11 44.5 0.0 7.6e-06 25.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 AJA92661.1 - 5.9e-11 42.5 0.6 7.4e-05 22.6 0.0 2.6 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 AJA92661.1 - 2.8e-07 30.7 0.6 0.0027 17.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 AJA92661.1 - 2e-06 27.5 1.7 0.035 13.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_2 PF08442.10 AJA92661.1 - 0.0064 16.1 0.1 0.035 13.6 0.1 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.6 AJA92661.1 - 0.019 14.5 0.0 0.46 9.9 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain TrkA_N PF02254.18 AJA92661.1 - 0.045 14.0 0.0 0.33 11.2 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain GARS_A PF01071.19 AJA92662.1 - 1.6e-76 256.4 0.3 2.2e-76 256.0 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 AJA92662.1 - 5.9e-32 110.3 0.1 1.2e-31 109.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 AJA92662.1 - 3.7e-30 104.0 0.0 8.4e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 AJA92662.1 - 3.8e-07 29.8 0.0 6.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AJA92662.1 - 7.3e-07 29.0 0.1 1.6e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 AJA92662.1 - 9.8e-07 29.0 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AJA92662.1 - 7.6e-06 25.6 0.1 1.3e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.10 AJA92662.1 - 0.00018 21.1 0.1 0.0003 20.4 0.1 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AJA92662.1 - 0.00053 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AJA92662.1 - 0.00091 18.5 0.2 0.002 17.4 0.2 1.6 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 AJA92662.1 - 0.029 13.9 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF448 PF04296.13 AJA92662.1 - 0.075 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF448) MS_channel PF00924.18 AJA92663.1 - 6.6e-29 100.9 0.1 1.3e-28 100.0 0.1 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel Sulf_transp PF04143.14 AJA92663.1 - 0.23 11.0 5.5 0.48 9.9 1.5 2.1 2 0 0 2 2 2 0 Sulphur transport Radical_SAM PF04055.21 AJA92664.1 - 2.9e-15 57.0 0.2 2.9e-15 57.0 0.2 2.5 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_14 PF13394.6 AJA92664.1 - 2.2e-06 27.8 0.0 2.2e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AJA92664.1 - 4.1e-06 27.1 0.0 1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain DegT_DnrJ_EryC1 PF01041.17 AJA92665.1 - 8.1e-96 321.5 0.0 9.8e-96 321.2 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AJA92665.1 - 1.7e-08 34.1 0.0 3.3e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AJA92665.1 - 9.1e-07 28.4 0.0 1.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 AJA92665.1 - 5.3e-05 22.1 0.2 6.2e-05 21.8 0.2 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Cys_Met_Meta_PP PF01053.20 AJA92665.1 - 0.00028 19.5 0.0 0.00044 18.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Surfac_D-trimer PF09006.11 AJA92665.1 - 0.025 14.4 0.0 0.73 9.8 0.0 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Aminotran_5 PF00266.19 AJA92665.1 - 0.027 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V OKR_DC_1 PF01276.20 AJA92665.1 - 0.034 12.9 0.0 0.073 11.8 0.0 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DUF2201_N PF13203.6 AJA92666.1 - 0.018 14.6 0.0 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Toprim_N PF08275.11 AJA92666.1 - 0.037 14.1 0.3 0.2 11.7 0.3 2.1 1 1 0 1 1 1 0 DNA primase catalytic core, N-terminal domain Abhydrolase_7 PF12715.7 AJA92667.1 - 4.6e-18 65.6 0.0 4e-17 62.6 0.0 2.0 1 1 0 1 1 1 1 Abhydrolase family Hydrolase_4 PF12146.8 AJA92667.1 - 4.5e-05 22.8 0.0 0.00013 21.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF5062 PF16691.5 AJA92667.1 - 0.086 13.0 0.0 5.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5062) DUF3139 PF11337.8 AJA92667.1 - 0.48 11.1 6.8 1 10.1 5.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) Fer4 PF00037.27 AJA92669.1 - 1e-07 31.4 15.7 0.00023 20.8 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJA92669.1 - 4.8e-06 27.1 4.8 1.3e-05 25.7 5.0 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJA92669.1 - 5.5e-05 23.2 5.6 0.00012 22.1 5.5 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJA92669.1 - 8.9e-05 22.6 4.0 0.00017 21.6 4.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJA92669.1 - 0.00011 22.3 5.1 0.00018 21.6 5.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AJA92669.1 - 0.0018 18.7 1.6 0.0045 17.4 1.6 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain ETF_QO PF05187.13 AJA92669.1 - 0.0022 18.1 0.5 0.0047 17.0 0.5 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Tenui_PVC2 PF06656.11 AJA92669.1 - 0.018 13.0 0.1 0.025 12.5 0.1 1.2 1 0 0 1 1 1 0 Tenuivirus PVC2 protein Fer4_16 PF13484.6 AJA92669.1 - 0.039 14.9 8.6 4 8.4 2.7 2.9 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain GLTSCR1 PF15249.6 AJA92669.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein Fer4_2 PF12797.7 AJA92669.1 - 0.43 10.8 10.1 0.52 10.5 0.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AJA92669.1 - 0.74 10.9 13.7 1.7 9.7 4.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AJA92669.1 - 1.1 9.5 14.3 0.3 11.2 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 AJA92669.1 - 2.4 8.9 6.6 8.1 7.2 0.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 AJA92669.1 - 3.6 8.2 6.7 23 5.6 2.1 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain HMGL-like PF00682.19 AJA92670.1 - 6.4e-89 298.0 0.1 1.3e-88 297.0 0.1 1.5 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AJA92670.1 - 1.5e-27 96.1 1.8 2.6e-27 95.3 1.8 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain AP_endonuc_2 PF01261.24 AJA92670.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Trypan_PARP PF05887.11 AJA92671.1 - 0.00012 22.1 10.6 0.00018 21.5 10.6 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Cuticle_1 PF08140.11 AJA92671.1 - 0.14 12.3 0.8 11 6.1 0.0 3.4 3 0 0 3 3 3 0 Crustacean cuticle protein repeat TonB_N PF16031.5 AJA92671.1 - 0.41 11.2 22.3 0.84 10.2 22.3 1.4 1 0 0 1 1 1 0 TonB polyproline region RtcB PF01139.17 AJA92673.1 - 1.5e-166 554.7 0.2 1.7e-166 554.5 0.2 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB DUF3492 PF11997.8 AJA92673.1 - 0.021 14.6 0.1 0.034 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Complex1_LYR PF05347.15 AJA92673.1 - 0.042 13.9 0.2 0.23 11.6 0.1 2.0 2 0 0 2 2 2 0 Complex 1 protein (LYR family) SepF PF04472.12 AJA92674.1 - 4.9e-11 42.7 0.3 5.6e-11 42.6 0.3 1.1 1 0 0 1 1 1 1 Cell division protein SepF Herpes_IE68 PF02479.16 AJA92674.1 - 0.0025 17.4 0.0 0.0027 17.3 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus immediate early protein H_kinase_N PF12282.8 AJA92674.1 - 0.008 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Signal transduction histidine kinase DRTGG PF07085.12 AJA92674.1 - 0.08 12.7 0.1 0.26 11.1 0.1 1.7 1 1 1 2 2 2 0 DRTGG domain Proteasome PF00227.26 AJA92675.1 - 1.3e-51 174.8 0.8 1.6e-51 174.5 0.8 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AJA92675.1 - 2.4e-11 43.1 0.8 1.7e-10 40.4 0.2 2.5 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Cupin_2 PF07883.11 AJA92676.1 - 2.2e-06 27.3 0.0 1.7e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Cupin domain Auxin_BP PF02041.16 AJA92676.1 - 3.9e-06 26.6 0.0 4.5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Auxin binding protein Cupin_1 PF00190.22 AJA92676.1 - 9.4e-06 25.3 0.0 1.1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Cupin SIMPL PF04402.14 AJA92677.1 - 3.3e-39 135.4 3.5 4.3e-39 135.1 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF4307 PF14155.6 AJA92677.1 - 0.11 12.3 0.2 0.29 11.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Glycos_transf_3 PF00591.21 AJA92678.1 - 4.7e-78 262.3 0.1 6e-78 261.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AJA92678.1 - 4.6e-08 32.8 0.2 1.6e-07 31.1 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Snf7 PF03357.21 AJA92678.1 - 1.4 8.5 6.1 0.57 9.8 1.8 2.2 2 0 0 2 2 2 0 Snf7 ABC_tran PF00005.27 AJA92680.1 - 5e-31 108.0 0.0 1.1e-30 106.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AJA92680.1 - 7.2e-10 39.2 0.7 1.3e-05 25.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 AJA92680.1 - 1.1e-06 29.3 1.2 1.1e-06 29.3 1.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 AJA92680.1 - 4e-05 23.5 4.6 0.0085 15.8 0.2 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 AJA92680.1 - 0.00073 20.1 5.4 0.0024 18.4 5.4 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AJA92680.1 - 0.0012 18.4 1.9 0.0012 18.3 0.2 1.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AJA92680.1 - 0.004 16.9 0.2 0.0093 15.7 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MukB PF04310.12 AJA92680.1 - 0.11 12.3 1.9 0.38 10.5 0.1 2.2 2 0 0 2 2 2 0 MukB N-terminal MMR_HSR1 PF01926.23 AJA92680.1 - 0.7 10.0 2.9 19 5.4 0.1 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase Helicase_C_2 PF13307.6 AJA92681.1 - 1.3e-18 67.7 0.5 1.7e-17 64.1 0.0 2.4 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 AJA92681.1 - 5.2e-12 46.1 2.7 7.8e-12 45.5 0.3 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 AJA92681.1 - 3.3e-05 23.6 5.5 0.00019 21.1 1.3 2.4 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 AJA92681.1 - 8.7e-05 22.3 1.8 0.12 12.2 0.0 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase AAA PF00004.29 AJA92681.1 - 0.0011 19.3 0.1 0.0085 16.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF4978 PF16349.5 AJA92681.1 - 0.019 14.6 0.2 0.054 13.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4978) AAA_22 PF13401.6 AJA92681.1 - 0.023 15.0 0.7 8.6 6.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 AJA92681.1 - 0.033 14.6 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 AJA92681.1 - 0.083 12.3 0.2 1.9 7.9 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein DUF4883 PF16224.5 AJA92682.1 - 0.0041 17.4 0.3 5.2 7.4 0.1 3.0 2 0 0 2 2 2 2 DOmain of unknown function (DUF4883) DUF4366 PF14283.6 AJA92682.1 - 0.0042 17.2 0.0 0.0094 16.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) ACT_4 PF13291.6 AJA92682.1 - 0.05 14.2 0.4 0.18 12.4 0.4 1.9 1 0 0 1 1 1 0 ACT domain Stk19 PF10494.9 AJA92682.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 MTS PF05175.14 AJA92683.1 - 3.5e-09 36.4 0.0 1e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 AJA92683.1 - 5.7e-07 29.5 0.0 1.1e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJA92683.1 - 6e-07 30.0 0.0 9.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJA92683.1 - 2.5e-06 28.1 0.1 4.4e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJA92683.1 - 5.6e-06 26.2 1.4 1.3e-05 25.0 1.4 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AJA92683.1 - 5.8e-05 22.2 0.0 6.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 AJA92683.1 - 0.00018 22.2 0.2 0.00037 21.2 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 AJA92683.1 - 0.00043 19.5 0.0 0.0006 19.0 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.19 AJA92683.1 - 0.0027 17.5 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 AJA92683.1 - 0.0033 17.4 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AJA92683.1 - 0.0074 15.7 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 AJA92683.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase AdoMet_MTase PF07757.13 AJA92683.1 - 0.1 12.9 0.1 0.41 11.0 0.0 1.9 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase RrnaAD PF00398.20 AJA92683.1 - 0.11 11.5 0.2 0.29 10.1 0.0 1.7 2 1 0 2 2 2 0 Ribosomal RNA adenine dimethylase NodS PF05401.11 AJA92683.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) UPF0020 PF01170.18 AJA92683.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 dUTPase_2 PF08761.11 AJA92684.1 - 6.8e-19 68.6 6.0 1.8e-14 54.2 0.4 2.0 1 1 1 2 2 2 2 dUTPase PRA-PH PF01503.17 AJA92684.1 - 9.5e-05 22.8 0.1 0.00012 22.5 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase DUF469 PF04320.14 AJA92684.1 - 0.073 13.9 0.1 0.095 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein with unknown function (DUF469) Epimerase_2 PF02350.19 AJA92685.1 - 2.4e-05 23.4 0.0 3.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Metallophos_2 PF12850.7 AJA92686.1 - 8.7e-28 97.6 0.2 9.8e-28 97.4 0.2 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AJA92686.1 - 5.6e-09 36.8 3.7 1.7e-07 32.0 1.1 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase SpoIIP PF07454.11 AJA92686.1 - 0.043 13.3 0.1 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Radical_SAM PF04055.21 AJA92687.1 - 1.2e-17 64.8 0.0 2e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 AJA92687.1 - 6.2e-15 55.0 0.1 6.2e-15 55.0 0.1 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 AJA92687.1 - 0.00078 19.4 0.1 0.002 18.1 0.1 1.7 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 AJA92687.1 - 0.0025 18.0 0.6 0.01 16.0 0.0 2.4 3 0 0 3 3 3 1 TRAM domain zf-PARP PF00645.18 AJA92687.1 - 0.0071 17.2 0.5 0.019 15.8 0.5 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF1059 PF06348.11 AJA92688.1 - 2.3e-09 37.3 0.0 2.5e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) Alba PF01918.21 AJA92689.1 - 3e-08 33.3 0.2 4.4e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 Alba Trypan_PARP PF05887.11 AJA92689.1 - 6.5e-05 22.9 17.1 8.5e-05 22.6 17.1 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Pex14_N PF04695.13 AJA92689.1 - 0.07 13.8 8.1 0.089 13.5 8.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Roughex PF06020.11 AJA92689.1 - 0.14 11.2 4.6 0.16 11.0 4.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein UPF0524 PF15823.5 AJA92689.1 - 0.37 10.2 0.1 0.37 10.2 0.1 1.7 2 0 0 2 2 2 0 UPF0524 of C3orf70 DUF3408 PF11888.8 AJA92689.1 - 0.55 10.4 3.6 0.84 9.8 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF4366 PF14283.6 AJA92689.1 - 0.94 9.5 3.4 1.4 9.0 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CCDC53 PF10152.9 AJA92689.1 - 1.9 8.9 7.4 2.8 8.3 7.4 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Neisseria_TspB PF05616.13 AJA92689.1 - 4.3 5.7 7.1 5.9 5.3 7.1 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein ROK PF00480.20 AJA92690.1 - 1.5e-69 234.7 0.2 1.7e-69 234.6 0.2 1.0 1 0 0 1 1 1 1 ROK family Hydant_A_N PF05378.13 AJA92690.1 - 0.00012 21.8 0.1 0.0002 21.1 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 AJA92690.1 - 0.0021 17.6 0.1 0.0098 15.4 0.1 2.0 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Glucokinase PF02685.16 AJA92690.1 - 0.012 14.6 1.2 0.052 12.5 1.2 1.9 1 1 0 1 1 1 0 Glucokinase DEDD_Tnp_IS110 PF01548.17 AJA92690.1 - 0.16 11.8 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Transposase Peptidase_M24 PF00557.24 AJA92691.1 - 3.5e-31 108.6 0.1 4e-31 108.3 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 GIT1_C PF12205.8 AJA92691.1 - 0.049 13.8 0.1 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term CTP_synth_N PF06418.14 AJA92691.1 - 0.057 12.7 0.1 0.086 12.1 0.1 1.3 1 0 0 1 1 1 0 CTP synthase N-terminus HSR PF03172.13 AJA92691.1 - 0.062 13.5 0.0 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 HSR domain DUF2070 PF09843.9 AJA92692.1 - 8.2e-121 404.0 0.5 1.1e-120 403.7 0.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) RseC_MucC PF04246.12 AJA92692.1 - 3 7.8 5.3 4 7.4 0.4 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Hexapep PF00132.24 AJA92693.1 - 4.9e-24 83.1 20.6 7.7e-10 38.1 0.3 4.1 3 1 1 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AJA92693.1 - 3.4e-16 58.7 11.8 1.8e-09 37.1 3.8 4.5 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase UPF0051 PF01458.17 AJA92694.1 - 4.7e-59 199.7 1.3 7e-59 199.1 1.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) zf-C4H2 PF10146.9 AJA92694.1 - 3.7 7.8 5.4 1.5 9.1 1.3 2.2 2 1 0 2 2 2 0 Zinc finger-containing protein SNase PF00565.17 AJA92696.1 - 2.6e-05 24.6 0.0 3.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue P-II PF00543.22 AJA92698.1 - 0.045 14.4 0.1 0.092 13.4 0.1 1.5 1 1 0 1 1 1 0 Nitrogen regulatory protein P-II Peptidase_S8 PF00082.22 AJA92699.1 - 5.7e-57 193.2 0.2 8.6e-57 192.7 0.2 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 AJA92699.1 - 1.8e-12 47.1 0.2 9.2e-12 44.8 0.0 2.3 3 0 0 3 3 3 1 PA domain Ham1p_like PF01725.16 AJA92700.1 - 1.3e-41 142.6 0.0 1.5e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family ETM PF17577.2 AJA92700.1 - 0.0088 16.6 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 1 ECORI-T site AA_kinase PF00696.28 AJA92701.1 - 4.3e-30 105.1 0.9 7.2e-30 104.3 0.9 1.3 1 1 0 1 1 1 1 Amino acid kinase family Citrate_synt PF00285.21 AJA92702.1 - 2.8e-126 421.4 0.0 3.2e-126 421.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF2811 PF10929.8 AJA92702.1 - 0.15 12.4 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) GTP_cyclohydroI PF01227.22 AJA92703.1 - 6.4e-66 221.2 0.2 7.2e-66 221.0 0.2 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 AJA92703.1 - 0.0046 17.1 0.0 0.01 16.0 0.0 1.6 2 0 0 2 2 2 1 QueF-like protein Fe-ADH_2 PF13685.6 AJA92704.1 - 1e-71 241.6 0.6 1.3e-71 241.2 0.6 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AJA92704.1 - 6.5e-23 81.1 0.2 6.8e-22 77.8 0.2 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 AJA92704.1 - 6.5e-06 25.5 0.3 0.0002 20.6 0.3 2.7 1 1 0 1 1 1 1 3-dehydroquinate synthase PASTA PF03793.19 AJA92704.1 - 0.0082 16.0 0.1 0.03 14.2 0.1 2.0 1 1 1 2 2 2 1 PASTA domain AIRC PF00731.20 AJA92704.1 - 0.012 15.2 2.4 0.015 14.8 0.4 2.1 2 0 0 2 2 2 0 AIR carboxylase DUF531 PF04407.12 AJA92704.1 - 0.055 13.6 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF531) Radical_SAM PF04055.21 AJA92705.1 - 2.8e-20 73.4 0.0 5.2e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 AJA92705.1 - 8.8e-19 67.6 0.1 2.1e-18 66.4 0.1 1.7 1 0 0 1 1 1 1 Wyosine base formation Fer4_14 PF13394.6 AJA92705.1 - 0.013 15.7 0.4 0.58 10.3 0.4 2.9 1 1 0 1 1 1 0 4Fe-4S single cluster domain LPG_synthase_TM PF03706.13 AJA92706.1 - 5.1e-33 114.9 17.0 6.1e-33 114.6 17.0 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region Sdh_cyt PF01127.22 AJA92707.1 - 1.2e-10 41.5 1.5 1.8e-10 40.9 1.5 1.3 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit tRNA-synt_1 PF00133.22 AJA92708.1 - 5.7e-62 209.8 3.2 7.1e-61 206.2 3.2 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AJA92708.1 - 6.2e-24 84.7 1.2 1.5e-23 83.4 1.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AJA92708.1 - 2.1e-23 82.7 0.2 2.1e-11 43.2 0.1 2.7 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AJA92708.1 - 2.5e-12 46.7 0.0 6.4e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 AJA92708.1 - 1.2e-10 41.2 5.8 4e-07 29.7 0.1 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain DUF659 PF04937.15 AJA92708.1 - 0.029 14.2 1.2 0.068 13.0 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Poty_PP PF08440.10 AJA92708.1 - 0.17 10.9 1.8 0.33 10.0 1.8 1.4 1 0 0 1 1 1 0 Potyviridae polyprotein DeoC PF01791.9 AJA92710.1 - 4.4e-49 167.2 0.0 5.2e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase PEP_mutase PF13714.6 AJA92710.1 - 0.063 12.7 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase YjgF_endoribonc PF14588.6 AJA92711.1 - 3e-33 115.1 0.0 3.3e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 AJA92711.1 - 1.1e-18 67.3 0.0 1.7e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Proton_antipo_M PF00361.20 AJA92712.1 - 5.8e-60 203.0 33.3 2.8e-54 184.3 27.9 2.9 3 0 0 3 3 3 2 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AJA92712.1 - 1.4e-12 47.5 1.8 1.4e-12 47.5 1.8 3.0 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_C PF01010.19 AJA92712.1 - 0.0017 18.0 0.1 0.35 10.5 0.0 2.4 1 1 1 2 2 2 2 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Oxidored_q2 PF00420.24 AJA92712.1 - 0.035 13.7 6.8 0.084 12.5 0.1 4.0 3 1 1 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ApoL PF05461.11 AJA92712.1 - 0.65 9.3 2.6 0.63 9.3 0.4 1.9 2 0 0 2 2 2 0 Apolipoprotein L HhH-GPD PF00730.25 AJA92713.1 - 2.4e-25 89.1 0.1 3.5e-25 88.6 0.1 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AJA92713.1 - 5.9e-09 35.4 0.0 1.7e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif AGOG PF09171.10 AJA92713.1 - 0.0015 17.9 1.4 0.0046 16.3 1.4 1.8 1 1 0 1 1 1 1 N-glycosylase/DNA lyase HHH_5 PF14520.6 AJA92713.1 - 0.0023 18.5 0.6 1 10.0 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain DUF2400 PF09674.10 AJA92713.1 - 0.0054 16.7 0.0 0.018 15.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2400) DUF5092 PF17010.5 AJA92713.1 - 0.043 13.7 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5092) HHH_2 PF12826.7 AJA92713.1 - 0.088 12.9 0.0 7.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AJA92713.1 - 0.26 11.7 3.4 0.44 10.9 3.4 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III KH_1 PF00013.29 AJA92714.1 - 1.5e-10 40.8 9.2 6.3e-06 25.9 2.6 2.3 2 0 0 2 2 2 2 KH domain Pox_M2 PF04887.12 AJA92714.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus M2 protein KH_2 PF07650.17 AJA92714.1 - 0.22 11.3 4.5 0.37 10.6 0.6 2.4 2 0 0 2 2 2 0 KH domain Pribosyltran PF00156.27 AJA92715.1 - 1.2e-08 34.6 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_3 PF15610.6 AJA92715.1 - 5.8e-05 22.5 0.1 7.9e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 PRTase ComF-like PRTase_2 PF15609.6 AJA92715.1 - 0.00012 21.7 0.1 0.00018 21.1 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.6 AJA92715.1 - 0.0091 15.5 0.1 0.015 14.7 0.1 1.5 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_S26e PF01283.19 AJA92716.1 - 1.3e-22 80.2 2.4 1.6e-22 80.0 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zinc_ribbon_11 PF11682.8 AJA92716.1 - 0.03 14.3 1.9 0.18 11.9 0.1 2.0 1 1 1 2 2 2 0 Probable zinc-ribbon zf-dskA_traR PF01258.17 AJA92716.1 - 0.053 13.5 0.1 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Lar_restr_allev PF14354.6 AJA92716.1 - 0.064 13.6 0.3 0.97 9.9 0.1 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar ADH_N PF08240.12 AJA92717.1 - 3.8e-31 107.2 0.5 5.9e-31 106.6 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AJA92717.1 - 6.4e-28 97.3 0.1 9.5e-28 96.8 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AJA92717.1 - 1.8e-11 45.2 0.0 2.9e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AJA92717.1 - 8.1e-08 32.0 0.1 2.7e-07 30.3 0.1 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Urocanase PF01175.18 AJA92717.1 - 0.00023 20.9 0.1 0.00043 20.0 0.1 1.3 1 0 0 1 1 1 1 Urocanase Rossmann-like domain PglD_N PF17836.1 AJA92717.1 - 0.013 16.2 0.4 0.044 14.4 0.4 2.0 1 0 0 1 1 1 0 PglD N-terminal domain AlaDh_PNT_C PF01262.21 AJA92717.1 - 0.019 14.3 0.2 0.029 13.7 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 AJA92717.1 - 0.053 13.1 0.2 0.08 12.5 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_16 PF10294.9 AJA92717.1 - 0.06 13.1 0.2 0.091 12.5 0.2 1.2 1 0 0 1 1 1 0 Lysine methyltransferase NAD_binding_2 PF03446.15 AJA92717.1 - 0.077 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MTS PF05175.14 AJA92717.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SIS PF01380.22 AJA92717.1 - 0.13 12.2 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 SIS domain Herpes_UL21 PF03252.13 AJA92718.1 - 0.036 12.8 0.0 0.041 12.6 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL21 Yopt PF09467.10 AJA92719.1 - 0.0094 16.0 0.1 0.028 14.5 0.1 1.8 1 0 0 1 1 1 1 Hypothetical protein Yopt KH_8 PF17903.1 AJA92719.1 - 0.13 12.4 2.1 0.49 10.5 0.1 2.6 2 0 0 2 2 2 0 Krr1 KH1 domain ATP-grasp_5 PF13549.6 AJA92720.1 - 1.2e-78 263.6 0.6 2.1e-78 262.8 0.6 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 AJA92720.1 - 2.7e-53 179.5 0.6 6e-53 178.4 0.6 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AJA92720.1 - 7.9e-23 81.2 0.4 3.9e-22 78.9 0.1 2.3 2 1 1 3 3 3 1 CoA binding domain ATP-grasp_2 PF08442.10 AJA92720.1 - 1.3e-06 28.2 2.2 2.8e-06 27.0 2.2 1.6 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.19 AJA92720.1 - 2.8e-06 27.9 0.7 1.6e-05 25.5 0.7 2.4 1 0 0 1 1 1 1 CoA binding domain Dak1_2 PF13684.6 AJA92720.1 - 0.00072 18.7 0.1 0.002 17.3 0.1 1.7 1 0 0 1 1 1 1 Dihydroxyacetone kinase family ATP-grasp PF02222.22 AJA92720.1 - 0.13 11.8 0.4 1.1 8.8 0.1 2.2 1 1 1 2 2 2 0 ATP-grasp domain DUF2540 PF10802.8 AJA92720.1 - 0.23 11.6 4.0 0.62 10.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2540) Aconitase_C PF00694.19 AJA92721.1 - 2.7e-35 121.5 0.0 4.3e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 AJA92721.1 - 0.014 15.1 0.0 0.25 10.9 0.0 2.1 1 1 0 1 1 1 0 Aconitate hydratase 2 N-terminus Synaptobrevin PF00957.21 AJA92721.1 - 0.21 11.4 2.0 0.31 10.8 0.2 1.9 2 0 0 2 2 2 0 Synaptobrevin HAD PF12710.7 AJA92722.1 - 1.6e-12 48.2 0.0 3.1e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AJA92722.1 - 9.8e-10 39.1 0.2 1.7e-08 35.0 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AJA92722.1 - 3e-07 30.4 0.3 4.2e-05 23.4 0.1 2.6 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AJA92722.1 - 0.00098 18.7 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Rpr2 PF04032.16 AJA92723.1 - 0.00021 21.5 0.2 0.00035 20.8 0.0 1.5 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain TF_Zn_Ribbon PF08271.12 AJA92723.1 - 0.00075 19.0 0.2 0.15 11.6 0.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding zf-C2H2_12 PF18658.1 AJA92723.1 - 0.03 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger C2H2-type TFIIS_C PF01096.18 AJA92723.1 - 0.04 13.8 0.6 5.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Ribosomal_L32p PF01783.23 AJA92723.1 - 0.045 14.0 0.8 0.25 11.7 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L32p protein family Lipase_GDSL_2 PF13472.6 AJA92724.1 - 9.6e-08 32.6 0.1 2.2e-07 31.4 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AJA92724.1 - 0.0012 18.8 1.6 0.029 14.3 1.6 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF2779 PF11074.8 AJA92724.1 - 0.059 13.8 2.0 0.077 13.5 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) Phage_holin_3_3 PF16083.5 AJA92725.1 - 0.085 13.0 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III Dak2 PF02734.17 AJA92726.1 - 0.04 13.8 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 DAK2 domain LANC_like PF05147.13 AJA92726.1 - 0.057 12.0 0.1 0.068 11.7 0.1 1.0 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Alba PF01918.21 AJA92727.1 - 0.042 13.7 0.2 0.095 12.5 0.0 1.7 2 0 0 2 2 2 0 Alba QueC PF06508.13 AJA92728.1 - 2.6e-09 36.9 0.6 3.2e-08 33.3 0.1 2.5 2 1 1 3 3 3 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AJA92728.1 - 2.9e-09 37.0 0.0 4.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.16 AJA92728.1 - 2.3e-08 33.3 0.2 2.3e-05 23.3 0.2 2.2 2 0 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 AJA92728.1 - 6.6e-08 32.0 0.0 1.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 AJA92728.1 - 9.4e-05 22.2 0.3 0.0027 17.5 0.3 2.2 1 1 0 1 1 1 1 PP-loop family ThiI PF02568.14 AJA92728.1 - 0.017 14.7 0.1 0.062 12.9 0.1 2.0 1 1 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 AJA92728.1 - 0.018 14.3 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase Asparaginase PF00710.20 AJA92729.1 - 9e-55 185.2 0.1 1.3e-54 184.7 0.1 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 AJA92729.1 - 1.9e-27 95.7 0.0 4.7e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain GatD_N PF18195.1 AJA92729.1 - 6.5e-21 73.4 4.6 9.6e-21 72.9 3.6 1.9 2 0 0 2 2 2 1 GatD N-terminal domain Thi4 PF01946.17 AJA92730.1 - 2.8e-65 219.8 0.0 3.3e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 AJA92730.1 - 9.7e-13 48.0 0.3 6.1e-06 25.6 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 AJA92730.1 - 3e-08 33.4 0.0 8.4e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AJA92730.1 - 8.3e-08 32.3 0.0 1.6e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AJA92730.1 - 6.2e-07 28.9 0.0 8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AJA92730.1 - 2.2e-06 27.2 0.0 3.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AJA92730.1 - 3.3e-06 26.1 0.0 4.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 AJA92730.1 - 4.3e-06 26.5 0.5 0.00021 21.0 0.2 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AJA92730.1 - 8.3e-05 22.0 0.1 0.00012 21.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AJA92730.1 - 0.00023 20.3 0.2 0.0071 15.4 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 AJA92730.1 - 0.0015 17.7 0.1 0.0022 17.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 AJA92730.1 - 0.018 13.9 0.0 1.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 AJA92730.1 - 0.024 14.9 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GDI PF00996.18 AJA92730.1 - 0.031 12.8 0.0 0.047 12.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.27 AJA92730.1 - 0.044 14.4 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AJA92730.1 - 0.064 12.6 0.0 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4366 PF14283.6 AJA92731.1 - 0.00053 20.0 1.4 0.001 19.1 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Podoplanin PF05808.11 AJA92731.1 - 0.0087 16.2 2.2 0.013 15.6 2.2 1.2 1 0 0 1 1 1 1 Podoplanin Ureide_permease PF07168.11 AJA92731.1 - 0.043 12.6 1.1 0.062 12.0 1.1 1.1 1 0 0 1 1 1 0 Ureide permease PMP22_Claudin PF00822.20 AJA92731.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Band_3_cyto PF07565.13 AJA92731.1 - 2.5 7.8 7.7 3.5 7.3 7.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ribosomal_L39 PF00832.20 AJA92732.1 - 2.3e-18 65.5 6.9 2.6e-18 65.3 6.9 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Ter PF05472.11 AJA92732.1 - 0.0047 16.0 1.2 0.0048 16.0 1.2 1.0 1 0 0 1 1 1 1 DNA replication terminus site-binding protein (Ter protein) PhosphMutase PF10143.9 AJA92733.1 - 2.2e-42 144.8 0.0 3.3e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 AJA92733.1 - 3.9e-30 105.0 0.5 4.8e-30 104.7 0.5 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 AJA92733.1 - 0.0006 19.5 0.0 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Rad51 PF08423.11 AJA92734.1 - 4.1e-28 98.3 0.3 7.1e-28 97.6 0.3 1.5 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 AJA92734.1 - 5.1e-11 42.4 2.0 5e-10 39.1 2.0 2.1 1 1 0 1 1 1 1 KaiC RecA PF00154.21 AJA92734.1 - 1e-05 25.1 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_14 PF13173.6 AJA92734.1 - 0.00032 20.7 1.7 0.00065 19.7 0.5 2.1 1 1 1 2 2 2 1 AAA domain Zot PF05707.12 AJA92734.1 - 0.00043 20.0 0.1 0.00056 19.6 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_24 PF13479.6 AJA92734.1 - 0.00066 19.5 0.1 0.0013 18.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 AJA92734.1 - 0.0018 17.7 0.4 0.0055 16.1 0.1 1.8 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 AJA92734.1 - 0.0043 17.3 0.2 0.0079 16.5 0.0 1.5 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 AJA92734.1 - 0.0052 16.5 0.2 0.072 12.8 0.1 2.5 1 1 1 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 AJA92734.1 - 0.0079 15.7 0.1 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 PhoH-like protein AAA_18 PF13238.6 AJA92734.1 - 0.011 16.3 0.6 0.026 15.1 0.6 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 AJA92734.1 - 0.011 15.2 0.2 0.021 14.2 0.2 1.5 1 1 0 1 1 1 0 Bacterial TniB protein AAA PF00004.29 AJA92734.1 - 0.013 16.0 0.4 0.024 15.0 0.4 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 AJA92734.1 - 0.015 14.8 0.0 0.09 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain Palm_thioest PF02089.15 AJA92734.1 - 0.065 13.1 1.6 0.065 13.1 1.6 1.3 1 1 0 1 1 1 0 Palmitoyl protein thioesterase AAA_33 PF13671.6 AJA92734.1 - 0.07 13.3 0.4 0.56 10.4 0.4 2.4 1 1 0 1 1 1 0 AAA domain TBP PF00352.21 AJA92735.1 - 2.6e-55 184.3 0.0 4.5e-27 93.8 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 AJA92735.1 - 8.6e-08 32.2 0.0 0.0018 18.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) AAA_5 PF07728.14 AJA92736.1 - 4.4e-25 88.3 0.1 6.1e-25 87.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 AJA92736.1 - 3.8e-13 49.4 0.0 5.4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 AJA92736.1 - 3.2e-08 34.1 0.0 5.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AJA92736.1 - 3.3e-07 30.4 0.1 6.5e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 AJA92736.1 - 4.5e-06 26.3 0.0 7.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 AJA92736.1 - 8.9e-06 26.2 0.1 1.8e-05 25.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 AJA92736.1 - 3.7e-05 23.5 0.1 7.2e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 Sigma-54 interaction domain ATPase_2 PF01637.18 AJA92736.1 - 5.6e-05 23.2 0.3 0.00014 21.8 0.1 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 AJA92736.1 - 9.9e-05 22.9 0.0 0.00023 21.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 AJA92736.1 - 0.00022 21.2 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 AJA92736.1 - 0.00025 21.3 0.1 0.00046 20.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain CbbQ_C PF08406.10 AJA92736.1 - 0.0004 20.6 0.0 0.00073 19.7 0.0 1.4 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal MCM PF00493.23 AJA92736.1 - 0.00073 18.7 0.0 0.0013 17.8 0.0 1.4 1 1 0 1 1 1 1 MCM P-loop domain AAA_11 PF13086.6 AJA92736.1 - 0.00079 19.3 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 AJA92736.1 - 0.0008 19.5 0.0 0.0017 18.5 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 AJA92736.1 - 0.00081 19.2 0.3 0.018 14.8 0.3 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 AJA92736.1 - 0.0017 18.5 0.1 0.0033 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 AJA92736.1 - 0.0039 16.6 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.6 AJA92736.1 - 0.004 17.4 0.0 0.013 15.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_6 PF12774.7 AJA92736.1 - 0.0043 16.1 0.0 0.022 13.7 0.0 2.0 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region NB-ARC PF00931.22 AJA92736.1 - 0.0044 16.2 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Mg_chelatase PF01078.21 AJA92736.1 - 0.0049 16.3 0.1 2.2 7.6 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 AJA92736.1 - 0.0056 16.4 0.5 0.036 13.8 0.5 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AJA92736.1 - 0.0076 16.8 0.6 0.035 14.6 0.1 2.1 2 1 1 3 3 2 1 ABC transporter TsaE PF02367.17 AJA92736.1 - 0.0088 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 AJA92736.1 - 0.011 15.2 0.0 0.027 13.9 0.0 1.6 2 0 0 2 2 1 0 Bacterial TniB protein AAA_24 PF13479.6 AJA92736.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 AJA92736.1 - 0.015 15.5 0.1 0.028 14.6 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_2 PF07724.14 AJA92736.1 - 0.016 15.3 0.6 0.059 13.5 0.6 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_29 PF13555.6 AJA92736.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 AJA92736.1 - 0.024 14.4 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 AJA92736.1 - 0.028 14.3 0.0 0.073 13.0 0.0 1.6 2 0 0 2 2 1 0 RsgA GTPase cobW PF02492.19 AJA92736.1 - 0.032 13.8 0.1 0.058 13.0 0.1 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 AJA92736.1 - 0.034 13.4 0.7 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Septin KAP_NTPase PF07693.14 AJA92736.1 - 0.035 13.4 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain NACHT PF05729.12 AJA92736.1 - 0.037 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 AJA92736.1 - 0.037 14.4 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_32 PF13654.6 AJA92736.1 - 0.053 12.3 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AJA92736.1 - 0.083 11.9 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 AJA92736.1 - 0.084 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 AJA92736.1 - 0.1 12.9 0.2 0.3 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.9 AJA92736.1 - 0.12 12.1 0.0 0.45 10.3 0.0 1.9 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 AJA92736.1 - 0.15 11.6 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.21 AJA92737.1 - 1.2e-52 179.0 0.2 1.3e-52 178.8 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ATP-synt_ab PF00006.25 AJA92738.1 - 7.6e-93 310.0 0.0 1e-92 309.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 AJA92738.1 - 2.4e-43 146.9 0.0 4.1e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 AJA92738.1 - 5.9e-14 52.3 0.2 1.5e-13 51.0 0.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.6 AJA92738.1 - 0.051 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.12 AJA92738.1 - 0.11 11.1 0.2 0.17 10.5 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RnfC_N PF13375.6 AJA92738.1 - 0.19 11.7 0.7 9.8 6.2 0.2 3.0 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain HTH_Tnp_Tc5 PF03221.16 AJA92739.1 - 0.049 13.7 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DUF58 PF01882.18 AJA92740.1 - 2e-21 76.1 0.0 3.4e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF58 VWA_2 PF13519.6 AJA92740.1 - 9.1e-07 29.5 0.1 5e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF3047 PF11249.8 AJA92740.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) DUF5104 PF17117.5 AJA92740.1 - 0.23 11.9 1.8 2.8 8.4 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5104) Ribosomal_L19e PF01280.20 AJA92741.1 - 1.4e-39 135.4 9.8 1.6e-39 135.3 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e EF-hand_8 PF13833.6 AJA92741.1 - 0.12 12.2 0.2 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair CelTOS PF18659.1 AJA92741.1 - 0.14 12.6 0.7 0.39 11.2 0.1 1.8 2 0 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites PPR_2 PF13041.6 AJA92742.1 - 0.087 13.0 0.8 7.2 6.9 0.0 2.3 2 0 0 2 2 2 0 PPR repeat family DUF1297 PF06973.12 AJA92743.1 - 1e-73 246.9 0.2 1.4e-73 246.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.12 AJA92743.1 - 6.4e-48 161.8 0.0 1.1e-47 161.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) ATP-grasp_3 PF02655.14 AJA92743.1 - 0.01 15.9 0.0 0.028 14.4 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain SCAN PF02023.17 AJA92743.1 - 0.14 12.0 0.3 0.29 11.0 0.3 1.4 1 0 0 1 1 1 0 SCAN domain DMPK_coil PF08826.10 AJA92744.1 - 0.2 11.8 6.0 0.09 12.9 3.2 1.9 2 0 0 2 2 2 0 DMPK coiled coil domain like DER1 PF04511.15 AJA92747.1 - 0.0065 16.4 3.0 0.0068 16.4 2.2 1.4 1 1 0 1 1 1 1 Der1-like family MerC PF03203.14 AJA92747.1 - 0.04 14.4 4.2 0.056 13.9 4.2 1.3 1 0 0 1 1 1 0 MerC mercury resistance protein 7TMR-DISM_7TM PF07695.11 AJA92747.1 - 0.05 13.5 12.7 0.072 13.0 12.7 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF5373 PF17343.2 AJA92747.1 - 2.3 8.0 12.7 2.9 7.7 12.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5373) DUF2070 PF09843.9 AJA92747.1 - 7.7 4.7 13.0 8.9 4.5 13.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Rhodanese PF00581.20 AJA92748.1 - 7.4e-40 135.8 0.1 2.8e-19 69.6 0.0 2.0 2 0 0 2 2 2 2 Rhodanese-like domain Ribosomal_S3Ae PF01015.18 AJA92749.1 - 5.4e-57 192.6 8.7 6.2e-57 192.5 8.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF1481 PF07356.12 AJA92749.1 - 0.01 15.6 0.2 0.015 15.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) TPR_1 PF00515.28 AJA92750.1 - 1.1e-21 75.7 8.1 7.3e-05 22.4 0.0 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 AJA92750.1 - 1.9e-19 68.1 3.1 0.0047 16.9 0.0 5.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 AJA92750.1 - 9.5e-14 51.5 0.0 0.00093 19.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 AJA92750.1 - 1e-13 50.6 4.5 0.00031 20.9 0.1 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 AJA92750.1 - 1.4e-12 47.9 2.4 3.8e-06 27.3 0.2 3.4 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 AJA92750.1 - 2.3e-12 46.1 4.2 0.046 13.9 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 AJA92750.1 - 3.5e-12 46.0 0.1 0.0047 17.6 0.0 5.0 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 AJA92750.1 - 7.4e-12 44.8 2.9 0.0001 21.9 0.0 3.8 3 1 1 4 4 4 3 TPR repeat TPR_7 PF13176.6 AJA92750.1 - 2.4e-11 42.8 0.7 0.099 12.7 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 AJA92750.1 - 5.7e-11 41.9 0.3 0.5 10.3 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 AJA92750.1 - 1.2e-07 32.2 0.0 0.084 13.5 0.0 3.3 2 1 2 4 4 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJA92750.1 - 1.5e-07 31.3 3.3 0.13 12.4 0.0 4.8 3 2 2 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 AJA92750.1 - 5.5e-07 29.7 0.0 0.051 13.7 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AJA92750.1 - 1e-06 28.9 4.9 0.00046 20.4 0.4 2.8 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 AJA92750.1 - 2.4e-06 27.7 0.1 1 9.4 0.0 4.2 2 1 0 3 3 3 2 Domain of Unknown Function (DUF3856) Coatomer_E PF04733.14 AJA92750.1 - 1.7e-05 24.4 4.7 0.036 13.5 0.4 3.0 1 1 2 3 3 3 2 Coatomer epsilon subunit TPR_20 PF14561.6 AJA92750.1 - 3.2e-05 24.2 3.3 0.014 15.7 0.1 3.4 2 1 2 4 4 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AJA92750.1 - 0.00086 19.8 0.6 1.4 9.3 0.1 3.1 1 1 1 2 2 2 1 Alkyl sulfatase dimerisation DUF4919 PF16266.5 AJA92750.1 - 0.0018 18.2 1.5 0.025 14.5 0.1 2.7 1 1 2 3 3 3 1 Domain of unknown function (DUF4919) TPR_6 PF13174.6 AJA92750.1 - 0.0026 18.3 3.6 5.2 7.9 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 AJA92750.1 - 0.0034 17.4 1.1 0.39 10.8 0.0 3.8 3 1 0 3 3 3 1 MIT (microtubule interacting and transport) domain BTAD PF03704.17 AJA92750.1 - 0.0089 16.5 0.1 11 6.5 0.0 3.3 1 1 3 4 4 4 0 Bacterial transcriptional activator domain COPI_C PF06957.11 AJA92750.1 - 0.015 14.1 0.1 0.039 12.7 0.1 1.6 1 1 1 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Fibrillarin PF01269.17 AJA92751.1 - 2e-85 285.5 0.1 2.4e-85 285.3 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 AJA92751.1 - 0.00075 19.3 0.0 0.00092 19.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 AJA92751.1 - 0.0036 17.1 0.0 0.0056 16.5 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Disulph_isomer PF06491.11 AJA92751.1 - 0.0076 16.4 0.1 0.012 15.7 0.1 1.2 1 0 0 1 1 1 1 Disulphide isomerase eIF-6 PF01912.18 AJA92752.1 - 2.8e-57 193.3 2.5 3.4e-57 193.0 2.5 1.0 1 0 0 1 1 1 1 eIF-6 family HlyD_2 PF12700.7 AJA92752.1 - 0.044 12.5 0.1 0.44 9.2 0.0 1.8 1 1 1 2 2 2 0 HlyD family secretion protein MBA1 PF07961.11 AJA92752.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 MBA1-like protein YjeF_N PF03853.15 AJA92753.1 - 4.2e-45 153.7 0.0 4.9e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus Thiolase_N PF00108.23 AJA92753.1 - 0.094 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain MEDS PF14417.6 AJA92754.1 - 6.5e-09 35.8 0.0 8.7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF1828 PF08861.10 AJA92754.1 - 0.066 13.5 1.0 0.28 11.5 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function DUF1828 EPSP_synthase PF00275.20 AJA92755.1 - 1.6e-101 340.1 0.1 1.9e-101 339.8 0.1 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) vATP-synt_E PF01991.18 AJA92755.1 - 0.041 13.3 0.1 0.077 12.4 0.1 1.4 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Clp_N PF02861.20 AJA92755.1 - 0.053 13.7 0.2 33 4.7 0.0 3.4 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component NMT1_3 PF16868.5 AJA92755.1 - 0.13 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family eRF1_1 PF03463.15 AJA92756.1 - 5.5e-20 71.7 1.2 9.8e-20 70.9 1.2 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 AJA92756.1 - 2.8e-10 40.6 0.7 1.5e-09 38.3 0.2 2.3 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_2 PF03464.15 AJA92756.1 - 0.00015 22.1 0.1 0.0004 20.7 0.0 1.8 1 1 0 1 1 1 1 eRF1 domain 2 DprA_WH PF17782.1 AJA92757.1 - 0.0018 18.3 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 DprA winged helix domain TFIIE_alpha PF02002.17 AJA92757.1 - 0.0037 17.1 0.9 0.0059 16.5 0.9 1.5 1 1 0 1 1 1 1 TFIIE alpha subunit Rrf2 PF02082.20 AJA92757.1 - 0.0043 17.4 0.0 0.0076 16.6 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator DUF4423 PF14394.6 AJA92757.1 - 0.0058 16.3 0.1 0.0083 15.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_34 PF13601.6 AJA92757.1 - 0.0062 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 AJA92757.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 AJA92757.1 - 0.051 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC DUF1676 PF07898.13 AJA92757.1 - 0.062 13.3 0.2 0.07 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Fe_dep_repress PF01325.19 AJA92757.1 - 0.067 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain CLZ PF16526.5 AJA92757.1 - 0.091 13.1 4.0 0.59 10.5 0.7 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLACT_WH PF17778.1 AJA92757.1 - 0.13 12.3 0.5 0.22 11.6 0.5 1.4 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain Myb_DNA-bind_4 PF13837.6 AJA92757.1 - 0.14 12.6 1.5 0.21 12.0 1.3 1.4 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Chordopox_L2 PF05803.12 AJA92757.1 - 0.18 11.7 0.5 4.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus L2 protein DUF1351 PF07083.11 AJA92758.1 - 0.034 13.9 0.6 0.053 13.3 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) PolC_DP2 PF03833.13 AJA92761.1 - 0.0085 14.0 0.2 0.0085 14.0 0.2 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 AJA92761.1 - 0.028 14.7 3.8 0.04 14.2 3.8 1.2 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-ribbon_3 PF13248.6 AJA92761.1 - 0.029 13.8 2.4 2.4 7.7 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 AJA92761.1 - 0.036 14.1 1.7 0.044 13.8 1.7 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NRDD PF13597.6 AJA92761.1 - 0.096 11.4 0.3 0.081 11.7 0.3 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase DUF3565 PF12088.8 AJA92761.1 - 0.22 11.5 2.5 0.54 10.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3565) PhnA_Zn_Ribbon PF08274.12 AJA92761.1 - 0.51 10.3 4.2 6.9 6.7 0.8 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-ACC PF17848.1 AJA92761.1 - 0.85 9.7 9.2 3.6 7.8 0.9 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Zn-ribbon_8 PF09723.10 AJA92761.1 - 2.5 8.3 6.6 13 6.0 6.6 1.9 1 1 0 1 1 1 0 Zinc ribbon domain Cupin_2 PF07883.11 AJA92762.1 - 2.3e-10 40.1 0.0 3.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 AJA92762.1 - 1.3e-06 28.1 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 AJA92762.1 - 8.7e-06 25.7 0.0 9.2e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 AJA92762.1 - 2.5e-05 24.2 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain GPI PF06560.11 AJA92762.1 - 0.0019 17.5 0.1 0.0034 16.7 0.1 1.4 1 1 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Ectoine_synth PF06339.12 AJA92762.1 - 0.0048 17.1 0.0 0.0053 16.9 0.0 1.1 1 0 0 1 1 1 1 Ectoine synthase Auxin_BP PF02041.16 AJA92762.1 - 0.055 13.1 0.0 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 Auxin binding protein CENP-C_C PF11699.8 AJA92762.1 - 0.086 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like Cupin_5 PF06172.11 AJA92762.1 - 0.11 12.6 0.0 0.48 10.6 0.0 2.1 1 1 0 1 1 1 0 Cupin superfamily (DUF985) MG2 PF01835.19 AJA92764.1 - 0.027 14.9 0.0 0.057 13.9 0.0 1.5 1 1 0 1 1 1 0 MG2 domain EMP24_GP25L PF01105.24 AJA92764.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Cadherin-like PF12733.7 AJA92764.1 - 0.23 12.0 2.2 0.32 11.6 0.6 1.8 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain DegT_DnrJ_EryC1 PF01041.17 AJA92765.1 - 1.5e-52 179.1 0.0 1.2e-35 123.6 0.0 2.0 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family CoA_binding_2 PF13380.6 AJA92766.1 - 3.5e-40 137.1 0.1 4.1e-40 136.9 0.1 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 AJA92766.1 - 1.5e-06 28.8 0.0 2.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain Glyco_hydro_57 PF03065.15 AJA92766.1 - 0.018 14.3 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 GFO_IDH_MocA PF01408.22 AJA92766.1 - 0.14 13.0 0.2 0.62 10.9 0.1 2.0 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold GATase_2 PF00310.21 AJA92767.1 - 0.12 11.0 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II DUF1771 PF08590.10 AJA92768.1 - 0.0021 18.4 8.1 0.32 11.4 0.0 3.5 4 0 0 4 4 4 2 Domain of unknown function (DUF1771) DLP_helical PF18709.1 AJA92768.1 - 0.01 15.1 0.1 0.02 14.1 0.1 1.5 1 0 0 1 1 1 0 Dynamin-like helical domain DEC-1_N PF04625.13 AJA92768.1 - 0.013 14.5 2.0 0.022 13.8 2.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CAP_N PF01213.19 AJA92768.1 - 0.014 14.9 0.4 0.028 13.9 0.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal OATP PF03137.20 AJA92768.1 - 0.13 10.5 0.0 0.22 9.8 0.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family LON_substr_bdg PF02190.16 AJA92770.1 - 7.2e-08 32.6 0.0 7.9e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DUF1002 PF06207.11 AJA92770.1 - 0.1 12.1 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Asn_synthase PF00733.21 AJA92771.1 - 2.5e-36 126.1 0.0 1.8e-22 80.5 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase zinc_ribbon_2 PF13240.6 AJA92771.1 - 0.00011 21.8 3.3 0.0002 21.0 3.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AJA92771.1 - 0.00025 21.0 2.9 0.00025 21.0 2.9 1.6 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 AJA92771.1 - 0.003 18.3 2.8 0.0058 17.4 2.8 1.5 1 0 0 1 1 1 1 zinc-ribbon family UPF0547 PF10571.9 AJA92771.1 - 0.0047 17.0 1.2 0.0047 17.0 1.2 1.9 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 NAD_synthase PF02540.17 AJA92771.1 - 0.022 13.9 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD synthase ATP_bind_3 PF01171.20 AJA92771.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 PP-loop family QueC PF06508.13 AJA92771.1 - 0.077 12.5 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 AJA92771.1 - 0.097 11.4 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.19 AJA92771.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family zf-ribbon_3 PF13248.6 AJA92771.1 - 0.35 10.4 2.4 0.69 9.4 2.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Formyl_trans_N PF00551.19 AJA92772.1 - 1.7e-46 158.2 0.1 2.4e-46 157.8 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase ACT_6 PF13740.6 AJA92772.1 - 3.1e-06 27.1 0.1 1.1e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 ACT domain Streptin-Immun PF11083.8 AJA92772.1 - 0.14 12.6 1.1 9 6.8 0.1 2.4 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein CotE PF10628.9 AJA92772.1 - 0.16 11.6 2.0 1 9.0 0.2 2.2 1 1 0 2 2 2 0 Outer spore coat protein E (CotE) ACT_4 PF13291.6 AJA92772.1 - 0.43 11.2 2.4 0.69 10.5 0.1 2.5 3 1 0 3 3 3 0 ACT domain M PF02370.16 AJA92773.1 - 0.04 14.5 2.3 0.04 14.5 2.3 2.9 3 0 0 3 3 3 0 M protein repeat CCDC53 PF10152.9 AJA92773.1 - 0.77 10.2 19.5 0.17 12.3 10.3 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Striatin PF08232.12 AJA92773.1 - 1.4 9.5 10.4 0.54 10.8 2.4 2.2 2 0 0 2 2 2 0 Striatin family UPF0126 PF03458.13 AJA92774.1 - 2.2e-41 139.6 25.7 6.7e-22 77.2 4.9 2.4 3 0 0 3 3 3 2 UPF0126 domain ThrE PF06738.12 AJA92774.1 - 9.7 5.5 18.3 1.7 8.0 1.9 2.2 1 1 1 2 2 2 0 Putative threonine/serine exporter RNA_pol_Rpb2_6 PF00562.28 AJA92775.1 - 9.5e-127 423.3 0.6 1.3e-126 422.8 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 AJA92775.1 - 1.7e-47 161.6 0.0 3e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 AJA92775.1 - 6e-29 100.3 0.0 1.3e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 AJA92775.1 - 1.7e-28 98.6 0.1 4.4e-28 97.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 AJA92775.1 - 5.6e-25 88.1 0.0 1.2e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 AJA92775.1 - 9.4e-18 64.3 0.2 2.1e-17 63.1 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 AJA92775.1 - 7.9e-08 32.7 1.2 4.8e-07 30.3 1.2 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF2318 PF10080.9 AJA92775.1 - 0.017 15.2 0.1 0.037 14.1 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) OrfB_Zn_ribbon PF07282.11 AJA92775.1 - 0.12 12.3 1.3 0.51 10.3 1.3 2.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_L37e PF01907.19 AJA92775.1 - 0.21 11.8 0.5 0.46 10.7 0.5 1.5 1 0 0 1 1 1 0 Ribosomal protein L37e SMC_N PF02463.19 AJA92776.1 - 2.2e-51 174.4 23.8 7.2e-30 104.1 0.1 4.3 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AJA92776.1 - 1.6e-18 67.9 11.6 1.6e-18 67.9 11.6 6.5 2 2 2 5 5 5 1 AAA domain SMC_hinge PF06470.13 AJA92776.1 - 1.1e-16 61.2 0.1 6.3e-16 58.7 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 AJA92776.1 - 4e-08 33.4 22.9 9e-06 25.7 0.7 4.4 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AJA92776.1 - 1e-07 32.0 15.0 1e-07 32.0 15.0 4.4 2 2 2 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 AJA92776.1 - 5.3e-06 26.1 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain KELK PF15796.5 AJA92776.1 - 0.0086 16.5 5.0 0.0086 16.5 5.0 8.8 5 3 3 8 8 8 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_16 PF13191.6 AJA92776.1 - 0.031 14.7 0.8 0.16 12.4 0.1 2.7 2 2 0 2 2 2 0 AAA ATPase domain APG6_N PF17675.1 AJA92776.1 - 0.95 10.0 94.4 0.036 14.6 3.4 8.0 3 2 5 8 8 8 0 Apg6 coiled-coil region ATG16 PF08614.11 AJA92776.1 - 1.2 9.4 86.7 2.3 8.4 7.2 6.8 2 2 4 6 6 6 0 Autophagy protein 16 (ATG16) DNase-RNase PF02577.14 AJA92777.1 - 1.8e-08 34.1 0.0 2.3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease Skp1_POZ PF03931.15 AJA92777.1 - 0.12 12.6 0.4 1.4 9.1 0.4 2.3 1 1 0 1 1 1 0 Skp1 family, tetramerisation domain Chorismate_bind PF00425.18 AJA92778.1 - 3.7e-97 324.9 0.1 5.8e-95 317.7 0.0 2.6 2 1 1 3 3 3 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 AJA92778.1 - 2.8e-23 82.7 0.5 5.2e-20 72.1 0.1 2.7 2 1 1 3 3 3 2 Anthranilate synthase component I, N terminal region DUF3090 PF11290.8 AJA92778.1 - 0.024 14.4 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) Usp PF00582.26 AJA92779.1 - 2.9e-28 99.1 0.0 3.5e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family CobS PF02654.15 AJA92780.1 - 1.8e-41 142.6 12.6 2e-41 142.4 12.6 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase GlutR_N PF05201.15 AJA92781.1 - 1.1e-37 129.0 0.0 2.2e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 AJA92781.1 - 2.9e-29 101.9 0.1 6.6e-29 100.7 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 AJA92781.1 - 9.1e-20 70.9 1.2 2.6e-19 69.5 1.2 1.8 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 AJA92781.1 - 0.00077 20.0 0.0 0.0023 18.5 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AJA92781.1 - 0.0085 15.5 0.0 0.027 13.8 0.0 1.9 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-cone PF03477.16 AJA92781.1 - 0.023 15.2 1.2 13 6.4 0.0 3.7 3 0 0 3 3 3 0 ATP cone domain Copper-bind PF00127.20 AJA92782.1 - 0.0021 18.4 0.0 0.0077 16.6 0.0 1.8 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJA92782.1 - 0.0031 17.6 0.0 0.0049 17.0 0.0 1.4 1 0 0 1 1 1 1 Cupredoxin-like domain PTPS_related PF10131.9 AJA92782.1 - 0.059 11.7 2.6 0.074 11.4 2.6 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DUF998 PF06197.13 AJA92782.1 - 9.4 5.8 16.7 89 2.6 16.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Glycos_transf_1 PF00534.20 AJA92783.1 - 1.8e-21 76.4 0.1 7.6e-21 74.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AJA92783.1 - 5.3e-18 65.8 0.0 1.5e-17 64.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AJA92783.1 - 4.7e-09 36.5 0.0 8.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 AJA92783.1 - 0.0004 19.3 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 2 UDP-N-acetylglucosamine 2-epimerase Glyco_transf_4 PF13439.6 AJA92783.1 - 0.0015 18.5 0.0 0.005 16.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 AJA92783.1 - 0.022 14.8 0.0 0.13 12.2 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferase 4-like Exosortase_EpsH PF09721.10 AJA92784.1 - 3.9e-06 26.6 26.5 6.4e-06 25.9 26.5 1.4 1 1 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) DUF998 PF06197.13 AJA92784.1 - 0.0072 15.9 5.9 0.0072 15.9 5.9 3.1 2 1 0 3 3 3 1 Protein of unknown function (DUF998) SdpI PF13630.6 AJA92784.1 - 3.3 7.9 0.0 3.3 7.9 0.0 4.5 3 1 1 4 4 4 0 SdpI/YhfL protein family PALP PF00291.25 AJA92785.1 - 1.1e-84 284.3 0.3 1.3e-84 284.1 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT_4 PF13291.6 AJA92785.1 - 0.00053 20.5 1.1 0.0025 18.4 0.8 2.1 2 0 0 2 2 2 1 ACT domain Thr_dehydrat_C PF00585.18 AJA92785.1 - 0.091 12.5 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase RNA_pol_Rpb4 PF03874.16 AJA92786.1 - 6.9e-09 36.1 4.4 9.3e-09 35.7 4.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Mrr_N PF14338.6 AJA92786.1 - 0.0087 16.2 0.6 1.6 8.9 0.2 2.2 1 1 1 2 2 2 2 Mrr N-terminal domain DUF421 PF04239.12 AJA92786.1 - 0.015 15.1 0.4 0.015 15.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF421) Blo-t-5 PF11642.8 AJA92786.1 - 0.018 15.0 0.6 0.026 14.5 0.4 1.5 1 1 0 1 1 1 0 Mite allergen Blo t 5 Integrase_Zn PF02022.19 AJA92786.1 - 0.038 14.0 0.3 0.22 11.5 0.1 2.0 2 0 0 2 2 2 0 Integrase Zinc binding domain DUF3895 PF13034.6 AJA92786.1 - 0.04 13.9 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) CdAMP_rec PF06153.11 AJA92787.1 - 0.01 16.0 0.3 0.017 15.3 0.3 1.5 1 1 0 1 1 1 0 Cyclic-di-AMP receptor NAT PF04768.13 AJA92787.1 - 0.063 12.9 0.6 0.078 12.6 0.6 1.2 1 0 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase OGG_N PF07934.12 AJA92788.1 - 1.3e-12 47.9 3.3 6.6e-07 29.5 0.1 2.9 2 1 1 3 3 3 2 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 AJA92788.1 - 8.5e-11 42.3 0.0 1.4e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AJA92788.1 - 0.0012 18.6 0.0 0.013 15.3 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AJA92788.1 - 0.049 14.3 0.0 1.5 9.5 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain Terminase_2 PF03592.16 AJA92788.1 - 0.051 14.0 0.2 0.26 11.7 0.0 2.1 3 0 0 3 3 3 0 Terminase small subunit PYRIN PF02758.16 AJA92788.1 - 0.16 12.2 0.7 16 5.7 0.0 2.7 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain Transket_pyr PF02779.24 AJA92789.1 - 3.1e-33 114.9 0.0 4.2e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AJA92789.1 - 5.3e-31 107.1 0.0 9.6e-31 106.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 AJA92789.1 - 0.0023 18.2 0.0 0.0052 17.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF2291 PF10054.9 AJA92790.1 - 0.096 12.4 0.4 0.16 11.6 0.4 1.3 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) PriA_3primeBD PF17764.1 AJA92790.1 - 0.11 12.4 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 3′ DNA-binding domain (3′BD) TF_Zn_Ribbon PF08271.12 AJA92790.1 - 0.13 11.8 5.5 0.47 10.0 1.3 3.1 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 AJA92790.1 - 0.21 11.7 9.2 0.13 12.4 0.5 3.2 3 0 0 3 3 3 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 AJA92790.1 - 1.3 9.0 6.1 14 5.7 5.6 2.7 1 1 0 1 1 1 0 Putative transposase DNA-binding domain HypA PF01155.19 AJA92790.1 - 3.9 7.5 10.0 0.96 9.5 1.4 3.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RecR PF02132.15 AJA92790.1 - 4.4 7.0 9.5 3.5 7.3 1.5 3.3 3 0 0 3 3 3 0 RecR protein Zn_Tnp_IS1595 PF12760.7 AJA92790.1 - 6 6.9 10.2 3.1e+02 1.5 10.2 2.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF4131 PF13567.6 AJA92791.1 - 0.037 13.7 4.7 0.5 10.0 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Pox_A28 PF04584.14 AJA92791.1 - 0.076 13.2 4.1 1.9 8.7 0.0 3.3 3 0 0 3 3 3 0 Poxvirus A28 family EptA_B_N PF08019.12 AJA92791.1 - 0.2 11.5 8.7 0.076 12.9 2.5 2.3 1 1 1 2 2 2 0 Phosphoethanolamine transferase EptA/EptB Tetraspanin PF00335.20 AJA92791.1 - 0.37 10.5 5.1 0.61 9.8 5.1 1.3 1 0 0 1 1 1 0 Tetraspanin family PhoU_div PF01865.16 AJA92792.1 - 4.3e-16 58.9 9.4 5.1e-16 58.7 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 WD40_alt PF14077.6 AJA92792.1 - 0.0067 16.3 0.5 0.028 14.3 0.1 2.2 2 0 0 2 2 2 1 Alternative WD40 repeat motif TSA PF03249.13 AJA92792.1 - 0.037 12.8 0.5 0.059 12.1 0.1 1.7 2 0 0 2 2 2 0 Type specific antigen TSC22 PF01166.18 AJA92792.1 - 0.21 11.9 3.9 0.41 11.0 0.1 3.2 3 1 0 3 3 3 0 TSC-22/dip/bun family Syntaxin_2 PF14523.6 AJA92792.1 - 0.21 11.9 6.1 2.3 8.6 0.4 2.6 1 1 0 2 2 2 0 Syntaxin-like protein MYO10_CC PF16735.5 AJA92792.1 - 0.51 10.5 5.1 0.93 9.6 0.4 3.0 3 0 0 3 3 3 0 Unconventional myosin-X coiled coil domain MCPsignal PF00015.21 AJA92792.1 - 0.8 9.5 7.4 5.2 6.8 0.3 2.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Cnn_1N PF07989.11 AJA92792.1 - 1.2 9.4 6.7 2.1 8.5 0.4 2.8 2 2 0 2 2 2 0 Centrosomin N-terminal motif 1 zf-C4H2 PF10146.9 AJA92792.1 - 1.6 9.0 9.8 13 6.0 4.3 2.4 1 1 0 2 2 2 0 Zinc finger-containing protein S6OS1 PF15676.5 AJA92792.1 - 2.3 6.6 7.9 0.29 9.5 3.3 1.7 2 1 0 2 2 2 0 Six6 opposite strand transcript 1 family DUF1192 PF06698.11 AJA92792.1 - 3.3 7.8 9.9 6.7 6.9 0.3 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) BST2 PF16716.5 AJA92792.1 - 7.6 7.2 6.6 12 6.6 0.6 3.0 2 2 0 2 2 2 0 Bone marrow stromal antigen 2 DUF3098 PF11297.8 AJA92793.1 - 0.013 15.0 0.3 0.014 15.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) RNA_pol_L_2 PF13656.6 AJA92794.1 - 3.7e-11 42.6 0.1 4.1e-11 42.5 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF3201 PF11447.8 AJA92794.1 - 0.15 11.6 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) Pcc1 PF09341.10 AJA92795.1 - 5e-05 23.3 0.0 6.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 IQ_SEC7_PH PF16453.5 AJA92795.1 - 0.039 13.9 0.1 0.039 13.9 0.1 1.1 1 0 0 1 1 1 0 PH domain ABC_tran PF00005.27 AJA92797.1 - 4.3e-39 134.2 1.0 2.5e-19 70.1 0.2 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 AJA92797.1 - 7.3e-11 41.9 1.4 0.00025 20.5 0.1 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 AJA92797.1 - 1.1e-10 41.2 2.8 1.1e-10 41.2 2.8 1.8 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 AJA92797.1 - 3.2e-09 36.2 12.0 8.2e-09 34.9 6.2 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 AJA92797.1 - 1.1e-08 34.8 13.7 1.7e-07 31.0 5.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AJA92797.1 - 2.4e-06 27.3 2.2 2.4e-06 27.3 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 AJA92797.1 - 5.5e-06 26.4 12.6 9.3e-06 25.7 12.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_21 PF13304.6 AJA92797.1 - 5.7e-06 26.3 4.3 0.78 9.5 0.4 4.4 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Fer4_10 PF13237.6 AJA92797.1 - 1.7e-05 24.8 11.9 3.4e-05 23.9 1.1 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AJA92797.1 - 2.7e-05 24.7 10.0 5.5e-05 23.7 10.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_15 PF13175.6 AJA92797.1 - 0.00016 21.5 1.4 0.17 11.6 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AJA92797.1 - 0.00081 19.1 0.1 0.14 11.9 0.0 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain NB-ARC PF00931.22 AJA92797.1 - 0.0023 17.1 0.5 0.55 9.4 0.1 2.5 2 0 0 2 2 2 1 NB-ARC domain Fer4_16 PF13484.6 AJA92797.1 - 0.0025 18.7 9.6 0.0055 17.6 1.0 2.7 1 1 1 2 2 2 1 4Fe-4S double cluster binding domain RsgA_GTPase PF03193.16 AJA92797.1 - 0.0041 17.0 0.4 0.087 12.7 0.0 2.6 3 0 0 3 3 2 1 RsgA GTPase His_Phos_1 PF00300.22 AJA92797.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_16 PF13191.6 AJA92797.1 - 0.0081 16.6 0.2 1.1 9.6 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain Fer4_9 PF13187.6 AJA92797.1 - 0.019 15.1 10.4 0.057 13.6 10.6 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain MMR_HSR1 PF01926.23 AJA92797.1 - 0.019 15.0 0.0 0.68 10.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 AJA92797.1 - 0.025 14.8 0.4 14 6.0 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_4 PF12800.7 AJA92797.1 - 0.029 14.9 1.8 0.029 14.9 1.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain RE_XcyI PF09571.10 AJA92797.1 - 0.03 13.6 0.1 0.081 12.2 0.1 1.7 1 0 0 1 1 1 0 XcyI restriction endonuclease Fer4_3 PF12798.7 AJA92797.1 - 0.031 15.2 4.9 0.031 15.2 4.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain DLIC PF05783.11 AJA92797.1 - 0.033 13.0 0.6 0.78 8.5 0.1 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Rad17 PF03215.15 AJA92797.1 - 0.085 12.8 0.1 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 AJA92797.1 - 0.33 11.4 7.0 3.4 8.1 1.3 3.2 2 2 0 2 2 2 0 AAA domain Fer4_17 PF13534.6 AJA92797.1 - 1.3 9.6 8.4 0.2 12.3 1.0 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AJA92797.1 - 2.2 8.8 7.9 0.4 11.2 1.1 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AJA92797.1 - 7.3 7.4 11.5 0.57 11.0 4.0 2.6 1 1 0 1 1 1 0 4Fe-4S single cluster domain Pentapeptide_4 PF13599.6 AJA92798.1 - 0.16 12.1 2.1 0.42 10.8 2.1 1.7 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) SRP54 PF00448.22 AJA92800.1 - 4.5e-69 232.0 0.3 9.4e-69 231.0 0.3 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 AJA92800.1 - 1.2e-25 89.9 2.9 1.2e-25 89.9 2.9 2.5 3 0 0 3 3 1 1 Signal peptide binding domain SRP54_N PF02881.19 AJA92800.1 - 2.3e-18 66.1 3.8 3.9e-18 65.4 0.8 2.7 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 AJA92800.1 - 6.3e-06 26.3 0.0 1.9e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 AJA92800.1 - 7.7e-05 23.1 0.6 0.00028 21.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 AJA92800.1 - 0.0001 21.4 0.2 0.00054 19.0 0.2 2.1 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB 6PF2K PF01591.18 AJA92800.1 - 0.0003 20.2 0.0 0.0006 19.2 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_31 PF13614.6 AJA92800.1 - 0.00037 20.5 0.3 0.0019 18.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 AJA92800.1 - 0.00037 20.4 0.5 0.0014 18.5 0.2 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.9 AJA92800.1 - 0.00073 19.3 0.8 0.59 9.9 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MipZ PF09140.11 AJA92800.1 - 0.00094 18.5 0.8 0.13 11.5 0.8 2.3 1 1 0 1 1 1 1 ATPase MipZ ParA PF10609.9 AJA92800.1 - 0.0016 18.0 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase APS_kinase PF01583.20 AJA92800.1 - 0.0018 18.2 0.2 0.005 16.7 0.0 1.7 2 0 0 2 2 1 1 Adenylylsulphate kinase MMR_HSR1 PF01926.23 AJA92800.1 - 0.0025 17.9 0.5 0.011 15.8 0.5 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 AJA92800.1 - 0.0026 17.9 0.0 0.0058 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 AJA92800.1 - 0.0027 17.3 0.9 0.0069 16.0 0.9 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 AJA92800.1 - 0.003 18.1 0.1 0.016 15.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AJA92800.1 - 0.0033 16.7 0.0 0.0057 15.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin VirC1 PF07015.11 AJA92800.1 - 0.0072 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 VirC1 protein NTPase_1 PF03266.15 AJA92800.1 - 0.01 15.8 0.8 0.032 14.1 0.7 2.0 1 1 0 1 1 1 0 NTPase DUF4317 PF14199.6 AJA92800.1 - 0.013 14.7 0.6 0.42 9.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4317) G-alpha PF00503.20 AJA92800.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.14 AJA92800.1 - 0.014 15.4 0.2 0.078 13.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 AJA92800.1 - 0.015 14.8 0.8 0.039 13.4 0.1 2.1 2 1 0 2 2 2 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 AJA92800.1 - 0.015 15.0 0.6 0.05 13.3 0.2 2.1 2 0 0 2 2 1 0 Thymidylate kinase AAA PF00004.29 AJA92800.1 - 0.016 15.7 1.2 0.16 12.4 0.1 3.0 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AJA92800.1 - 0.016 14.9 0.1 0.045 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 AJA92800.1 - 0.018 14.5 0.2 0.12 11.9 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family CLP1_P PF16575.5 AJA92800.1 - 0.028 14.2 0.2 2.5 7.9 0.2 2.7 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRPRB PF09439.10 AJA92800.1 - 0.032 13.7 0.6 2.6 7.4 0.2 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 AJA92800.1 - 0.034 14.5 0.1 0.073 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 AJA92800.1 - 0.052 13.1 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 AJA92800.1 - 0.053 13.8 0.1 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AJA92800.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain LytR_C PF13399.6 AJA92800.1 - 0.067 14.2 0.0 0.29 12.1 0.1 2.1 2 0 0 2 2 1 0 LytR cell envelope-related transcriptional attenuator ABC_tran PF00005.27 AJA92800.1 - 0.076 13.5 0.9 0.29 11.6 0.1 2.1 2 0 0 2 2 2 0 ABC transporter AAA_26 PF13500.6 AJA92800.1 - 0.12 12.2 0.6 2.1 8.1 0.6 2.6 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 AJA92800.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain CaM_bdg_C0 PF10562.9 AJA92800.1 - 0.19 11.8 0.4 0.53 10.4 0.4 1.8 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit ArsA_ATPase PF02374.15 AJA92800.1 - 0.34 10.1 5.7 2.2 7.4 0.4 3.2 3 0 0 3 3 3 0 Anion-transporting ATPase DNA_pol3_delta2 PF13177.6 AJA92801.1 - 4.5e-17 62.3 1.1 1.9e-12 47.2 0.5 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 AJA92801.1 - 2.5e-12 47.3 0.1 5.7e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 AJA92801.1 - 3.9e-08 33.6 0.3 1.6e-07 31.6 0.2 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain RuvB_N PF05496.12 AJA92801.1 - 1.8e-07 31.1 0.0 6.9e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 AJA92801.1 - 1.7e-05 24.9 0.3 4.6e-05 23.4 0.1 1.8 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 AJA92801.1 - 0.00013 22.4 0.3 0.00093 19.6 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 AJA92801.1 - 0.00023 21.2 0.2 0.00055 20.0 0.2 1.8 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 AJA92801.1 - 0.00026 21.3 0.1 0.00064 20.0 0.1 1.7 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 AJA92801.1 - 0.0009 19.1 0.6 0.0019 18.0 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 AJA92801.1 - 0.0026 17.6 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AJA92801.1 - 0.0047 16.3 0.0 0.21 10.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MAP PF03642.13 AJA92801.1 - 0.0089 16.3 0.2 0.041 14.2 0.2 2.1 1 0 0 1 1 1 1 MAP domain AAA_22 PF13401.6 AJA92801.1 - 0.011 16.1 2.5 0.91 9.8 0.1 2.9 2 1 1 3 3 3 0 AAA domain PhoH PF02562.16 AJA92801.1 - 0.011 15.2 0.1 2.4 7.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_5 PF07728.14 AJA92801.1 - 0.014 15.4 0.4 0.11 12.5 0.4 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 AJA92801.1 - 0.02 13.9 0.1 0.3 9.9 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 AJA92801.1 - 0.023 14.5 0.6 0.62 9.8 0.1 2.6 1 1 0 2 2 2 0 DEAD/DEAH box helicase Sigma54_activat PF00158.26 AJA92801.1 - 0.024 14.3 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SSE PF00437.20 AJA92801.1 - 0.025 13.6 0.0 0.052 12.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PTPlike_phytase PF14566.6 AJA92801.1 - 0.027 14.6 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Shikimate_dh_N PF08501.11 AJA92801.1 - 0.036 14.3 0.0 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Shikimate dehydrogenase substrate binding domain Ribosomal_S6e PF01092.19 AJA92801.1 - 0.041 13.9 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S6e NACHT PF05729.12 AJA92801.1 - 0.046 13.6 0.5 3 7.7 0.2 2.6 2 1 1 3 3 2 0 NACHT domain Arc_PepC PF06819.11 AJA92801.1 - 0.047 13.8 7.0 2.1 8.5 0.1 3.5 3 1 1 4 4 4 0 Archaeal Peptidase A24 C-terminal Domain ResIII PF04851.15 AJA92801.1 - 0.058 13.4 0.3 1.3 9.0 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 AJA92801.1 - 0.074 12.9 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 AJA92801.1 - 0.079 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 AJA92801.1 - 0.082 12.3 0.2 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 AJA92801.1 - 0.13 12.6 0.7 2.3 8.5 0.1 2.6 2 2 0 2 2 2 0 AAA domain Inositol_P PF00459.25 AJA92802.1 - 2.7e-49 168.1 0.4 3.5e-49 167.7 0.4 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Snf7 PF03357.21 AJA92803.1 - 3.9e-06 26.6 6.2 5.8e-06 26.0 6.2 1.3 1 0 0 1 1 1 1 Snf7 Prominin PF05478.11 AJA92803.1 - 0.012 13.7 3.5 0.49 8.3 0.0 2.0 1 1 1 2 2 2 0 Prominin Serine_rich PF08824.10 AJA92803.1 - 0.02 14.9 0.6 0.045 13.8 0.6 1.6 1 0 0 1 1 1 0 Serine rich protein interaction domain DASH_Duo1 PF08651.10 AJA92803.1 - 0.02 14.7 2.2 0.3 10.9 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 SesA PF17107.5 AJA92803.1 - 0.032 14.4 0.3 0.62 10.3 0.3 2.4 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Flagellin_C PF00700.21 AJA92803.1 - 0.042 14.2 6.0 0.53 10.7 2.0 2.6 2 2 0 2 2 2 0 Bacterial flagellin C-terminal helical region DASH_Dad4 PF08650.10 AJA92803.1 - 0.11 12.5 1.1 1.9 8.5 0.6 2.5 1 1 1 2 2 2 0 DASH complex subunit Dad4 OmpH PF03938.14 AJA92803.1 - 0.11 12.8 4.2 0.48 10.8 2.0 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Rx_N PF18052.1 AJA92803.1 - 0.21 11.9 1.5 2.2 8.6 0.1 2.5 1 1 1 2 2 2 0 Rx N-terminal domain NPV_P10 PF05531.12 AJA92803.1 - 0.27 11.7 6.3 7.4 7.1 2.1 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 AJA92803.1 - 0.75 10.1 8.4 8.2 6.8 0.5 3.5 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) AIRS_C PF02769.22 AJA92804.1 - 1.4e-46 158.5 0.1 3.3e-26 92.3 0.2 2.2 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AJA92804.1 - 3.7e-38 130.1 0.3 1.2e-18 67.6 0.4 2.4 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain FGAR-AT_linker PF18072.1 AJA92804.1 - 3.4e-08 33.9 1.6 1.3e-07 32.0 1.7 2.1 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain TPP_enzyme_M PF00205.22 AJA92804.1 - 0.071 12.9 0.0 8.4 6.1 0.0 3.1 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain Polyketide_cyc PF03364.20 AJA92805.1 - 6e-06 26.5 0.0 7.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AJA92805.1 - 1.8e-05 25.0 0.0 2.1e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Enolase_C PF00113.22 AJA92807.1 - 9.4e-59 199.1 1.1 1.3e-58 198.6 1.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 AJA92807.1 - 3.3e-20 72.6 0.2 1.1e-19 70.9 0.2 2.0 1 1 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 AJA92807.1 - 6.8e-06 25.8 0.0 1.9e-05 24.3 0.0 1.7 2 1 0 2 2 2 1 Enolase C-terminal domain-like tRNA-synt_1 PF00133.22 AJA92809.1 - 5e-106 355.3 0.3 6.9e-105 351.6 0.3 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AJA92809.1 - 8.1e-32 110.3 3.4 1.9e-31 109.1 1.1 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AJA92809.1 - 7.4e-22 77.6 2.8 4.1e-13 48.8 0.0 3.6 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AJA92809.1 - 0.0016 18.0 0.0 0.089 12.3 0.0 2.8 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 DUF1773 PF08593.10 AJA92809.1 - 0.1 13.7 0.2 1.5 9.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function Ferritin PF00210.24 AJA92810.1 - 6.4e-30 103.9 1.3 8e-30 103.6 1.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 AJA92810.1 - 0.00016 22.1 0.5 0.00028 21.3 0.5 1.5 1 1 0 1 1 1 1 Rubrerythrin ANAPC8 PF04049.13 AJA92810.1 - 0.063 13.3 0.0 0.1 12.7 0.0 1.3 1 1 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 ZapB PF06005.12 AJA92811.1 - 0.18 12.3 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Pribosyltran_N PF13793.6 AJA92813.1 - 2.8e-24 85.3 0.3 1.1e-23 83.4 0.0 2.1 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 AJA92813.1 - 2.7e-14 53.6 6.3 1.2e-13 51.6 1.6 2.9 1 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AJA92813.1 - 5.7e-14 51.9 1.2 5.7e-14 51.9 1.2 2.4 2 1 1 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AJA92813.1 - 1.3e-05 24.7 0.0 2.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AJA92813.1 - 0.003 17.1 0.1 0.0055 16.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase Asp_Glu_race PF01177.22 AJA92813.1 - 0.0035 17.2 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Thiolase_N PF00108.23 AJA92814.1 - 1e-20 74.2 0.0 2.4e-20 73.0 0.0 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AJA92814.1 - 2.2e-11 43.5 0.6 1.1e-10 41.3 0.1 2.4 2 2 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AJA92814.1 - 8.1e-05 22.3 0.8 0.03 13.9 0.4 2.9 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AJA92814.1 - 0.0079 16.0 0.0 0.39 10.6 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 AJA92814.1 - 0.15 12.1 1.2 1.4 9.0 0.6 2.7 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain SUI1 PF01253.22 AJA92815.1 - 6.1e-18 65.1 0.1 8.1e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF3877 PF12993.7 AJA92815.1 - 0.058 13.3 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) PG_binding_2 PF08823.11 AJA92815.1 - 0.068 13.5 0.1 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Img2 PF05046.14 AJA92815.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) BNR_2 PF13088.6 AJA92816.1 - 1.9e-11 43.8 0.0 1.7e-10 40.7 0.0 2.2 1 1 0 1 1 1 1 BNR repeat-like domain BNR_4 PF15892.5 AJA92816.1 - 0.01 15.2 0.5 0.01 15.2 0.5 2.8 1 1 0 2 2 2 0 BNR repeat-containing family member BNR PF02012.20 AJA92816.1 - 1.3 9.3 20.0 0.83 9.9 0.3 6.3 6 0 0 6 6 6 0 BNR/Asp-box repeat Ribosomal_S14 PF00253.21 AJA92817.1 - 0.014 15.2 0.4 7.7 6.4 0.0 3.1 2 1 0 2 2 2 0 Ribosomal protein S14p/S29e Prok-RING_4 PF14447.6 AJA92817.1 - 0.16 11.9 0.7 0.16 11.9 0.7 4.6 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 PHD_4 PF16866.5 AJA92817.1 - 0.29 11.2 14.9 4 7.6 1.9 3.3 2 1 1 3 3 3 0 PHD-finger Radical_SAM PF04055.21 AJA92819.1 - 6.4e-16 59.2 0.0 1.2e-15 58.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DUF2714 PF10896.8 AJA92820.1 - 0.011 15.8 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2714) Aminotran_3 PF00202.21 AJA92821.1 - 6.6e-92 308.3 0.0 8.2e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AJA92821.1 - 5.7e-05 22.5 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2183 PF09949.9 AJA92821.1 - 0.052 13.9 0.0 3.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) Inositol_P PF00459.25 AJA92823.1 - 4e-27 95.4 0.0 4.8e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AJA92823.1 - 0.0021 17.6 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain RNA_pol_Rpb1_1 PF04997.12 AJA92825.1 - 3.1e-93 312.5 0.0 6.3e-93 311.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 AJA92825.1 - 3.5e-83 279.1 2.4 5.8e-83 278.4 1.8 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 AJA92825.1 - 6.3e-72 241.2 0.0 1.2e-71 240.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AJA92825.1 - 1.8e-33 115.7 0.2 5e-33 114.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AJA92825.1 - 1.1e-23 83.3 0.1 1.1e-23 83.3 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Peptidase_C34 PF05413.11 AJA92825.1 - 0.0047 17.2 0.3 0.62 10.4 0.1 3.3 4 0 0 4 4 4 1 Putative closterovirus papain-like endopeptidase DUF5339 PF17274.2 AJA92826.1 - 1.7 9.6 17.6 1.1 10.1 2.1 4.3 4 0 0 4 4 4 0 Family of unknown function (DUF5339) Adenylsucc_synt PF00709.21 AJA92827.1 - 2.3e-81 273.9 0.3 1.5e-39 136.1 0.0 3.0 1 1 2 3 3 3 3 Adenylosuccinate synthetase GFO_IDH_MocA PF01408.22 AJA92829.1 - 1.6e-26 93.5 0.0 2.6e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AJA92829.1 - 7.1e-07 29.2 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 AJA92829.1 - 0.054 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AJA92829.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TylF PF05711.11 AJA92830.1 - 1.8e-22 79.9 0.1 2.3e-22 79.6 0.1 1.0 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 AJA92830.1 - 1.5e-08 35.6 0.0 2.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DS PF01916.17 AJA92831.1 - 1.8e-78 263.7 0.0 2.2e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Capsule_synth PF05159.14 AJA92832.1 - 1.7e-07 31.0 0.1 2.9e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein ALAD PF00490.21 AJA92834.1 - 1.2e-137 458.3 0.9 1.4e-137 458.1 0.9 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase FtsJ PF01728.19 AJA92835.1 - 7.2e-51 172.8 0.0 8.3e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 AJA92835.1 - 0.00022 21.1 0.0 0.00028 20.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJA92835.1 - 0.00046 20.0 0.1 0.004 17.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 AJA92835.1 - 0.0018 17.9 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 AJA92835.1 - 0.002 18.8 0.1 0.0053 17.4 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Radical_SAM PF04055.21 AJA92836.1 - 8.9e-19 68.5 0.2 2.7e-18 66.9 0.2 1.9 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 AJA92836.1 - 7.4e-05 22.9 0.0 0.00021 21.4 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AJA92836.1 - 0.0099 16.2 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Peptidase_C71 PF12386.8 AJA92836.1 - 0.027 14.1 0.1 1.1 8.8 0.0 2.9 2 1 0 2 2 2 0 Pseudomurein endo-isopeptidase Pei Rpr2 PF04032.16 AJA92837.1 - 1.4e-14 54.1 0.2 1.7e-14 53.8 0.2 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain C1_1 PF00130.22 AJA92837.1 - 0.008 16.0 0.6 0.013 15.4 0.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PRESAN PF09687.10 AJA92837.1 - 0.053 14.1 0.3 0.081 13.5 0.3 1.3 1 0 0 1 1 1 0 Plasmodium RESA N-terminal zf-ribbon_3 PF13248.6 AJA92837.1 - 0.086 12.3 0.9 4.6 6.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_10 PF16588.5 AJA92837.1 - 1.4 8.7 9.0 0.24 11.1 1.4 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger DUF21 PF01595.20 AJA92838.1 - 4.7e-49 166.5 0.2 7.2e-49 165.9 0.2 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AJA92838.1 - 1e-17 63.9 1.9 2.3e-17 62.8 0.4 2.1 1 1 1 2 2 2 1 Transporter associated domain CBS PF00571.28 AJA92838.1 - 5.7e-16 58.7 0.5 6.6e-07 29.7 0.1 2.7 2 0 0 2 2 2 2 CBS domain DUF2889 PF11136.8 AJA92838.1 - 0.18 12.1 0.1 0.76 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2889) Ribosomal_L27A PF00828.19 AJA92839.1 - 4.8e-15 56.4 0.6 7.2e-15 55.8 0.6 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TAF4 PF05236.14 AJA92840.1 - 0.046 13.5 10.5 0.061 13.1 10.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family APG6_N PF17675.1 AJA92840.1 - 0.19 12.2 0.1 0.19 12.2 0.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region FbpA PF05833.11 AJA92840.1 - 0.7 8.6 0.0 0.7 8.6 0.0 2.1 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) HisKA_3 PF07730.13 AJA92840.1 - 1.2 9.7 4.6 38 4.9 0.0 2.6 2 1 0 2 2 2 0 Histidine kinase DUF3892 PF13031.6 AJA92841.1 - 7.3e-07 29.7 0.2 7.3e-07 29.7 0.2 3.3 4 1 0 4 4 4 1 Protein of unknown function (DUF3892) ECF_trnsprt PF12822.7 AJA92843.1 - 0.004 17.3 3.3 0.0043 17.2 3.3 1.0 1 0 0 1 1 1 1 ECF transporter, substrate-specific component DUF3169 PF11368.8 AJA92843.1 - 0.058 12.9 2.0 0.062 12.8 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF378 PF04070.12 AJA92843.1 - 0.13 12.2 3.4 0.14 12.0 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF378) Heliorhodopsin PF18761.1 AJA92843.1 - 0.3 10.4 3.8 0.35 10.2 3.8 1.0 1 0 0 1 1 1 0 Heliorhodopsin Amidase PF01425.21 AJA92844.1 - 4.3e-139 464.3 0.1 4.9e-139 464.2 0.1 1.0 1 0 0 1 1 1 1 Amidase RrnaAD PF00398.20 AJA92846.1 - 1.2e-39 136.1 4.8 1.5e-39 135.7 4.8 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 AJA92846.1 - 7.2e-06 25.9 0.0 2.1e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 AJA92846.1 - 0.011 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.6 AJA92846.1 - 0.034 14.9 0.0 0.087 13.5 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 AJA92846.1 - 0.11 13.2 0.0 0.25 12.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CTP_synth_N PF06418.14 AJA92847.1 - 3.1e-117 390.6 0.8 4.2e-117 390.2 0.8 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 AJA92847.1 - 7.9e-51 172.5 0.0 1.3e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJA92847.1 - 3.4e-11 43.3 0.0 7.8e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 AJA92847.1 - 0.0056 16.7 0.0 0.027 14.5 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DJ-1_PfpI PF01965.24 AJA92847.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Polysacc_synt_2 PF02719.15 AJA92848.1 - 2.2e-97 325.8 0.1 2.7e-97 325.5 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AJA92848.1 - 1.1e-25 90.5 0.0 9.3e-25 87.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AJA92848.1 - 5.3e-20 71.6 0.0 4.1e-17 62.1 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AJA92848.1 - 1e-16 61.3 0.0 9e-15 54.9 0.0 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AJA92848.1 - 7.3e-13 48.2 0.0 4.1e-11 42.5 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AJA92848.1 - 8.3e-12 45.4 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AJA92848.1 - 2.1e-09 36.9 0.4 7.8e-06 25.2 0.1 3.1 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 AJA92848.1 - 1.1e-05 25.0 0.0 2.3e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 AJA92848.1 - 0.00012 21.7 0.0 0.00033 20.3 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Shikimate_DH PF01488.20 AJA92848.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AJA92848.1 - 0.00018 22.0 0.0 0.00075 20.0 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 AJA92848.1 - 0.00023 21.2 0.0 0.00052 20.0 0.0 1.6 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 AJA92848.1 - 0.0047 17.3 0.0 0.065 13.7 0.0 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_syn_2C PF08485.10 AJA92848.1 - 0.01 15.5 0.2 0.025 14.3 0.2 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal PMT_2 PF13231.6 AJA92849.1 - 7.5e-13 49.0 15.3 7.5e-13 49.0 15.3 3.0 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2723 PF11028.8 AJA92849.1 - 0.0085 16.0 9.2 0.0085 16.0 9.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) DUF2973 PF11189.8 AJA92849.1 - 0.019 15.0 0.3 0.071 13.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Peptidase_M60 PF13402.6 AJA92849.1 - 0.12 11.8 0.8 0.17 11.4 0.1 1.6 2 0 0 2 2 2 0 Peptidase M60, enhancin and enhancin-like Holin_SPP1 PF04688.13 AJA92849.1 - 7 6.9 7.6 4 7.7 0.3 3.3 3 0 0 3 3 3 0 SPP1 phage holin DnaJ PF00226.31 AJA92850.1 - 4.2e-20 71.6 1.5 7.9e-20 70.8 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain UBA_2 PF08587.11 AJA92850.1 - 0.069 13.3 0.1 17 5.6 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) DUF1673 PF07895.11 AJA92850.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) AKNA PF12443.8 AJA92850.1 - 0.25 12.0 2.8 0.58 10.8 1.6 2.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor CAP_assoc_N PF14504.6 AJA92851.1 - 0.03 14.1 0.4 0.069 12.9 0.2 1.6 1 1 0 1 1 1 0 CAP-associated N-terminal PDT PF00800.18 AJA92852.1 - 2.9e-54 183.7 0.3 6.3e-54 182.6 0.2 1.6 2 0 0 2 2 2 1 Prephenate dehydratase ACT PF01842.25 AJA92852.1 - 4.7e-07 29.5 0.0 8.9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AJA92852.1 - 0.096 13.3 0.1 0.26 11.9 0.1 1.8 1 0 0 1 1 1 0 ACT domain SAICAR_synt PF01259.18 AJA92853.1 - 6.5e-71 238.9 0.0 7.8e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase HMG_CoA_synt_C PF08540.10 AJA92854.1 - 1.3e-34 120.1 0.3 2.4e-34 119.3 0.3 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 AJA92854.1 - 8.9e-28 97.3 0.1 1.5e-27 96.5 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF1726 PF08351.11 AJA92854.1 - 0.027 14.4 0.0 0.18 11.8 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1726) Ribosomal_S14 PF00253.21 AJA92855.1 - 7.2e-05 22.5 4.9 0.00015 21.5 5.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S14p/S29e NikR_C PF08753.11 AJA92856.1 - 6.4e-14 51.9 0.6 1e-13 51.2 0.6 1.3 1 0 0 1 1 1 1 NikR C terminal nickel binding domain RHH_1 PF01402.21 AJA92856.1 - 1.9e-05 24.4 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family DUF1387 PF07139.11 AJA92856.1 - 0.072 12.8 0.1 0.52 10.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1387) Ribosomal_S11 PF00411.19 AJA92857.1 - 2.2e-42 143.9 2.0 3.2e-42 143.4 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 DUF3898 PF13037.6 AJA92857.1 - 0.002 18.2 0.1 0.0028 17.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3898) CBM_25 PF03423.13 AJA92857.1 - 0.0098 16.1 0.1 0.018 15.3 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) DivIVA PF05103.13 AJA92858.1 - 0.0023 18.0 7.8 0.0031 17.6 7.8 1.2 1 0 0 1 1 1 1 DivIVA protein Gp58 PF07902.11 AJA92858.1 - 0.011 14.0 5.2 0.013 13.8 5.2 1.0 1 0 0 1 1 1 0 gp58-like protein FAM184 PF15665.5 AJA92858.1 - 0.022 14.6 1.5 0.022 14.6 1.5 2.0 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Phage_Mu_Gam PF07352.12 AJA92858.1 - 0.025 14.5 8.0 0.57 10.1 0.4 2.0 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF883 PF05957.13 AJA92858.1 - 0.026 15.1 4.9 0.056 14.1 1.5 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Muted PF14942.6 AJA92858.1 - 0.027 14.8 5.6 0.034 14.5 5.6 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Phasin PF05597.11 AJA92858.1 - 0.031 14.3 5.7 0.048 13.7 4.1 1.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) V-ATPase_G_2 PF16999.5 AJA92858.1 - 0.045 14.2 8.3 0.24 11.8 8.3 2.3 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit YabA PF06156.13 AJA92858.1 - 0.1 13.2 3.4 0.15 12.7 3.4 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Het-C PF07217.11 AJA92858.1 - 0.16 10.5 5.4 0.17 10.4 5.4 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Baculo_PEP_C PF04513.12 AJA92858.1 - 0.17 11.9 5.3 0.32 11.1 1.2 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 AJA92858.1 - 0.21 11.9 3.1 2.1 8.6 3.1 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ApoLp-III PF07464.11 AJA92858.1 - 0.22 11.6 10.2 0.67 10.0 10.2 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) RNase_J_C PF17770.1 AJA92858.1 - 0.23 12.5 4.2 0.24 12.5 1.6 2.0 1 1 2 3 3 3 0 Ribonuclease J C-terminal domain Spc24 PF08286.11 AJA92858.1 - 0.24 11.6 9.6 2.2 8.6 9.6 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 ATP-synt_B PF00430.18 AJA92858.1 - 0.25 11.5 6.8 0.39 10.8 6.8 1.4 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2863 PF11062.8 AJA92858.1 - 0.25 9.7 3.0 0.26 9.6 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) YtxH PF12732.7 AJA92858.1 - 0.89 10.1 8.3 4 8.1 8.3 2.0 1 1 0 1 1 1 0 YtxH-like protein TMPIT PF07851.13 AJA92858.1 - 1 8.6 6.1 1.1 8.4 6.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 AJA92858.1 - 1.6 8.8 6.8 2.2 8.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sox_N PF12444.8 AJA92858.1 - 1.8 9.8 7.0 3 9.0 7.0 1.6 1 1 0 1 1 1 0 Sox developmental protein N terminal FlaC_arch PF05377.11 AJA92858.1 - 3.6 8.0 10.2 0.41 11.1 2.7 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Pigment_DH PF06324.11 AJA92859.1 - 0.15 12.2 0.1 0.34 11.1 0.1 1.5 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) DUF915 PF06028.11 AJA92861.1 - 0.0056 16.1 0.1 0.009 15.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) CbiA PF01656.23 AJA92862.1 - 1.5e-20 73.5 0.0 2.3e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AJA92862.1 - 3.6e-19 69.4 0.1 1.2e-17 64.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 AJA92862.1 - 0.006 16.5 0.0 0.043 13.7 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SelA PF03841.13 AJA92862.1 - 0.0096 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase TPR_1 PF00515.28 AJA92863.1 - 3.3e-17 61.5 7.1 1.2e-06 28.1 0.0 4.9 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 AJA92863.1 - 1.1e-13 50.6 0.1 4.9e-05 22.9 0.0 3.5 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.17 AJA92863.1 - 1.1e-12 47.0 5.0 0.0043 17.1 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 AJA92863.1 - 5.1e-11 41.9 7.8 0.0067 16.6 0.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 AJA92863.1 - 4.9e-10 39.5 1.0 0.0014 18.9 0.0 3.9 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 AJA92863.1 - 9.4e-09 35.7 2.0 0.0043 17.5 0.0 3.5 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 AJA92863.1 - 6e-08 32.6 0.8 0.85 10.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AJA92863.1 - 8.3e-08 32.4 0.0 2.2 9.3 0.0 4.2 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 AJA92863.1 - 2.7e-06 27.0 2.0 2.2 8.5 0.0 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 AJA92863.1 - 1.2e-05 25.8 0.0 0.16 12.7 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 AJA92863.1 - 3.7e-05 23.7 3.1 1.6 8.9 0.5 3.7 3 1 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 AJA92863.1 - 0.00013 22.0 0.0 0.074 13.2 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 AJA92863.1 - 0.00018 21.9 1.3 11 6.9 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AJA92863.1 - 0.00039 20.6 0.8 0.0014 18.8 0.1 2.1 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 AJA92863.1 - 0.0013 17.7 0.4 0.23 10.3 0.0 2.1 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.6 AJA92863.1 - 0.0023 18.4 0.7 0.02 15.4 0.1 2.0 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation PknG_TPR PF16918.5 AJA92863.1 - 0.0044 15.8 0.0 0.0055 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_10 PF13374.6 AJA92863.1 - 0.012 15.4 0.0 38 4.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJA92863.1 - 0.072 13.2 0.6 31 4.7 0.0 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 AJA92863.1 - 0.76 9.3 0.0 0.76 9.3 0.0 3.4 4 1 0 4 4 4 0 SHNi-TPR NIF PF03031.18 AJA92864.1 - 6e-05 22.9 0.1 0.00021 21.1 0.0 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Acetyltransf_1 PF00583.25 AJA92864.1 - 0.00045 20.4 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acid_PPase PF12689.7 AJA92864.1 - 0.00089 19.1 5.1 0.0014 18.5 1.3 2.7 2 1 0 2 2 2 1 Acid Phosphatase FR47 PF08445.10 AJA92864.1 - 0.0098 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 AJA92864.1 - 0.011 15.9 0.9 0.033 14.3 0.1 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RMI1_C PF16099.5 AJA92864.1 - 0.065 13.1 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Acetyltransf_7 PF13508.7 AJA92864.1 - 0.088 13.2 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MAF_flag10 PF01973.18 AJA92865.1 - 1.8e-35 122.1 0.7 2.5e-35 121.7 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF115 Guanylin PF02058.15 AJA92865.1 - 0.01 16.3 0.0 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Guanylin precursor TPK_catalytic PF04263.16 AJA92865.1 - 0.056 13.5 0.1 0.099 12.7 0.1 1.6 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain THF_DHG_CYH_C PF02882.19 AJA92865.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TPR_1 PF00515.28 AJA92866.1 - 7.2e-18 63.6 0.3 1.7e-11 43.4 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 AJA92866.1 - 2e-16 58.7 0.1 2e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 AJA92866.1 - 5.1e-13 48.5 0.1 4.1e-06 26.4 0.0 2.1 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 AJA92866.1 - 1.1e-11 43.9 0.1 8.1e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 AJA92866.1 - 1.7e-10 41.3 0.0 1.9e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 AJA92866.1 - 2.4e-09 36.9 0.3 2.2e-06 27.6 0.0 2.4 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 AJA92866.1 - 4.7e-09 35.6 0.1 0.0034 17.3 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 AJA92866.1 - 9.5e-09 35.4 0.1 2.8e-08 33.9 0.1 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 AJA92866.1 - 1.1e-08 35.0 0.0 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 AJA92866.1 - 1.8e-07 31.7 0.0 2.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 AJA92866.1 - 3.6e-07 30.4 0.2 0.028 15.2 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 AJA92866.1 - 2.1e-05 24.2 0.4 0.012 15.5 0.1 2.3 2 1 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 AJA92866.1 - 0.00036 20.5 0.0 0.31 11.1 0.0 2.1 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 AJA92866.1 - 0.0061 15.5 0.0 0.0071 15.3 0.0 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 SHNi-TPR PF10516.9 AJA92866.1 - 0.01 15.3 1.7 0.46 10.0 0.7 2.4 2 1 0 2 2 2 1 SHNi-TPR Coatomer_E PF04733.14 AJA92866.1 - 0.017 14.5 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit DUF3856 PF12968.7 AJA92866.1 - 0.024 14.7 0.0 0.053 13.6 0.0 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 AJA92866.1 - 0.038 14.1 0.2 5.7 7.1 0.0 2.6 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat PHO4 PF01384.20 AJA92867.1 - 6.5e-80 268.7 32.7 3.5e-79 266.3 32.7 1.8 1 1 0 1 1 1 1 Phosphate transporter family Lum_binding PF00677.17 AJA92868.1 - 2e-43 146.2 4.9 1.2e-22 79.7 0.1 2.0 2 0 0 2 2 2 2 Lumazine binding domain GCH_III PF05165.12 AJA92869.1 - 1.6e-51 174.9 0.0 2e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase III mCpol PF18182.1 AJA92869.1 - 3.3e-05 24.2 0.8 0.016 15.5 0.0 2.3 2 0 0 2 2 2 2 minimal CRISPR polymerase domain Guanylate_cyc PF00211.20 AJA92869.1 - 0.0022 17.7 1.8 0.0032 17.1 0.6 1.9 2 1 1 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain IFT20 PF14931.6 AJA92869.1 - 0.035 14.3 0.4 0.13 12.4 0.1 2.0 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 NOG1 PF06858.14 AJA92869.1 - 0.097 12.5 0.4 0.57 10.0 0.2 2.4 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) ARL2_Bind_BART PF11527.8 AJA92869.1 - 0.4 10.8 4.9 0.64 10.1 0.0 2.9 2 1 0 2 2 2 0 The ARF-like 2 binding protein BART Proteasome PF00227.26 AJA92870.1 - 1.3e-51 174.9 0.4 1.7e-51 174.5 0.4 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AJA92870.1 - 1.8e-13 49.9 0.1 1.8e-13 49.9 0.1 2.9 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature adh_short PF00106.25 AJA92871.1 - 5.4e-51 172.8 0.0 6.9e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AJA92871.1 - 3.8e-38 131.4 0.0 5.9e-38 130.7 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJA92871.1 - 6.9e-07 29.4 0.0 1.4e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 AJA92871.1 - 4e-06 26.4 0.0 0.00015 21.2 0.0 2.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RseC_MucC PF04246.12 AJA92872.1 - 0.0081 16.1 1.4 0.0097 15.9 0.6 1.5 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC DUF2207 PF09972.9 AJA92872.1 - 0.094 11.5 0.3 0.11 11.2 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GvpH PF05455.11 AJA92872.1 - 0.17 11.9 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpH Ribosomal_L22 PF00237.19 AJA92873.1 - 1.1e-22 80.2 0.4 1.4e-22 79.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RelB PF04221.12 AJA92873.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RelB antitoxin HTH_ParB PF17762.1 AJA92873.1 - 0.18 11.7 2.9 0.83 9.5 2.9 2.0 1 1 0 1 1 1 0 HTH domain found in ParB protein Fer4_14 PF13394.6 AJA92874.1 - 2e-15 56.9 3.0 5e-15 55.7 0.3 2.3 1 1 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AJA92874.1 - 5.8e-12 46.0 0.9 1.5e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 AJA92874.1 - 3.1e-11 43.9 0.0 5.5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Lipocalin_4 PF13648.6 AJA92874.1 - 0.099 13.6 0.7 0.099 13.6 0.7 1.9 2 0 0 2 2 2 0 Lipocalin-like domain F420H2_quin_red PF04075.14 AJA92875.1 - 8.4e-08 32.4 0.0 1.2e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 F420H(2)-dependent quinone reductase DUF2255 PF10012.9 AJA92875.1 - 0.015 15.5 0.1 0.016 15.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) AhpC-TSA PF00578.21 AJA92876.1 - 4.8e-26 91.1 0.3 6e-26 90.8 0.3 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJA92876.1 - 2.7e-13 49.9 0.3 3.4e-13 49.5 0.3 1.1 1 0 0 1 1 1 1 Redoxin ELFV_dehydrog PF00208.21 AJA92878.1 - 1.5e-64 218.0 0.6 2.4e-64 217.4 0.6 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 AJA92878.1 - 1.3e-47 160.9 0.0 2.4e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF1374 PF07118.11 AJA92879.1 - 0.1 13.1 6.3 0.42 11.1 1.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1374) LD_cluster3 PF18180.1 AJA92879.1 - 1.5 8.5 3.7 2.9 7.5 0.0 2.5 3 0 0 3 3 3 0 SLOG cluster3 family FdtA PF05523.11 AJA92880.1 - 1.6e-18 66.7 0.2 2e-18 66.4 0.2 1.0 1 0 0 1 1 1 1 WxcM-like, C-terminal Cupin_2 PF07883.11 AJA92880.1 - 0.0056 16.4 0.0 0.0094 15.6 0.0 1.5 1 1 0 1 1 1 1 Cupin domain Methyltransf_31 PF13847.6 AJA92882.1 - 5.3e-18 65.3 0.0 7.9e-18 64.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJA92882.1 - 2e-17 63.5 0.0 2.9e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJA92882.1 - 1.5e-16 60.9 0.0 3.5e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJA92882.1 - 5.3e-16 59.2 0.0 1e-15 58.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJA92882.1 - 6.7e-15 55.5 0.0 1.3e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AJA92882.1 - 7.8e-10 38.5 0.0 3.4e-09 36.5 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase small domain DREV PF05219.12 AJA92882.1 - 8.7e-09 34.9 0.0 1.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 AJA92882.1 - 9.8e-09 34.9 0.0 2.8e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 AJA92882.1 - 8.6e-08 31.5 0.0 1.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 AJA92882.1 - 1.3e-07 31.4 0.0 7.9e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 AJA92882.1 - 5.9e-06 26.0 0.0 9.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 AJA92882.1 - 7.1e-06 25.6 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 AJA92882.1 - 2.6e-05 23.8 0.1 4.8e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 AJA92882.1 - 0.00044 20.3 0.1 0.00073 19.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AJA92882.1 - 0.0016 17.9 0.1 0.0044 16.4 0.1 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 AJA92882.1 - 0.0041 16.5 0.0 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain TPMT PF05724.11 AJA92882.1 - 0.0092 15.7 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 AJA92882.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.13 AJA92882.1 - 0.016 15.5 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase POR PF01558.18 AJA92882.1 - 0.03 14.4 0.0 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Methyltransf_8 PF05148.15 AJA92882.1 - 0.059 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase N2227 PF07942.12 AJA92882.1 - 0.079 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Methyltransf_4 PF02390.17 AJA92882.1 - 0.087 12.3 0.0 0.37 10.2 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase CheR PF01739.18 AJA92882.1 - 0.088 12.3 0.0 12 5.3 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Spectrin_like PF18373.1 AJA92883.1 - 0.034 14.2 0.1 0.049 13.7 0.1 1.4 1 1 0 1 1 1 0 Spectrin like domain CorA PF01544.18 AJA92884.1 - 8.3e-28 97.5 4.6 1.1e-27 97.1 4.6 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FA_desaturase PF00487.24 AJA92884.1 - 0.0072 16.2 0.1 0.01 15.7 0.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase PMC2NT PF08066.12 AJA92884.1 - 0.096 13.4 2.1 0.41 11.4 0.4 2.5 2 1 0 2 2 2 0 PMC2NT (NUC016) domain Prok-RING_4 PF14447.6 AJA92885.1 - 0.0018 18.1 0.5 0.0023 17.8 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 AJA92885.1 - 0.0019 18.0 2.0 0.0028 17.5 2.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 AJA92885.1 - 0.047 13.7 0.2 0.051 13.6 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 AJA92885.1 - 0.41 10.2 5.7 0.96 9.0 0.5 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding SOR_SNZ PF01680.17 AJA92886.1 - 4.2e-97 323.9 3.1 5.3e-97 323.6 3.1 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 AJA92886.1 - 6.2e-07 29.0 3.6 1.5e-05 24.4 0.3 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 AJA92886.1 - 1e-06 28.4 0.4 0.0026 17.2 0.0 3.2 2 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 AJA92886.1 - 0.00037 20.0 3.1 0.086 12.2 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase IGPS PF00218.21 AJA92886.1 - 0.00089 18.5 0.0 0.022 13.9 0.0 2.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase Dus PF01207.17 AJA92886.1 - 0.0025 16.9 1.0 0.6 9.2 0.3 2.3 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 AJA92886.1 - 0.0069 15.6 2.3 0.11 11.7 0.0 3.0 2 2 1 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase Phos_pyr_kin PF08543.12 AJA92886.1 - 0.015 14.7 0.4 0.025 14.0 0.4 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase OMPdecase PF00215.24 AJA92886.1 - 0.06 12.9 1.1 1.3 8.5 0.2 2.6 2 1 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Thymidylate_kin PF02223.17 AJA92887.1 - 1e-34 119.9 0.1 1.1e-34 119.7 0.1 1.0 1 0 0 1 1 1 1 Thymidylate kinase HPHLAWLY PF14925.6 AJA92887.1 - 0.0033 16.2 4.3 0.53 8.9 0.7 2.5 1 1 1 3 3 3 2 Domain of unknown function tRNA_anti-codon PF01336.25 AJA92888.1 - 2.5e-10 40.2 0.1 0.026 14.5 0.0 3.4 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 AJA92888.1 - 9.2e-06 25.5 0.1 0.04 13.6 0.0 2.4 2 0 0 2 2 2 2 Cell division control protein 24, OB domain 3 POT1PC PF16686.5 AJA92888.1 - 0.0015 18.4 0.0 1.6 8.6 0.0 2.8 3 0 0 3 3 3 2 ssDNA-binding domain of telomere protection protein PadR PF03551.14 AJA92889.1 - 3.7e-11 42.8 0.0 7.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.6 AJA92889.1 - 0.00016 21.6 0.7 0.00042 20.2 0.1 2.0 2 1 0 2 2 2 1 Winged helix-turn-helix Mrr_N PF14338.6 AJA92889.1 - 0.00053 20.1 0.1 0.0048 17.0 0.0 2.3 2 0 0 2 2 2 1 Mrr N-terminal domain Hemocyanin_M PF00372.19 AJA92889.1 - 0.00076 18.7 2.0 0.0012 18.1 2.0 1.3 1 0 0 1 1 1 1 Hemocyanin, copper containing domain RTP PF02334.16 AJA92889.1 - 0.0022 18.6 0.7 0.03 15.0 0.0 2.3 1 1 0 2 2 2 1 Replication terminator protein DUF4364 PF14277.6 AJA92889.1 - 0.03 14.1 1.1 0.071 12.9 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4364) AphA_like PF14557.6 AJA92889.1 - 0.032 13.9 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Copper-bind PF00127.20 AJA92890.1 - 8.6e-16 58.2 0.1 1.5e-07 31.8 0.0 2.3 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu-oxidase_3 PF07732.15 AJA92890.1 - 1.1e-12 48.0 0.4 1.9e-05 24.7 0.0 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 AJA92890.1 - 4.8e-10 39.5 0.0 0.00095 19.2 0.0 2.4 2 0 0 2 2 2 2 Cupredoxin-like domain SoxE PF06525.11 AJA92890.1 - 1.1e-07 31.5 1.4 0.015 14.8 0.1 3.1 2 2 0 2 2 2 2 Sulfocyanin (SoxE) domain Cu-oxidase_2 PF07731.14 AJA92890.1 - 6.1e-07 29.3 0.0 0.012 15.3 0.0 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu_bind_like PF02298.17 AJA92890.1 - 5.1e-05 23.2 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 2 Plastocyanin-like domain CHU_C PF13585.6 AJA92890.1 - 0.058 13.4 0.1 12 6.1 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of CHU protein family DUF5599 PF18141.1 AJA92890.1 - 0.22 11.8 0.0 14 6.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5599) PPC PF04151.15 AJA92890.1 - 0.86 10.7 7.7 2.5 9.3 0.5 3.0 2 1 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Dioxygenase_N PF04444.14 AJA92891.1 - 0.0081 16.0 0.1 4 7.4 0.0 2.3 2 0 0 2 2 2 2 Catechol dioxygenase N terminus Glyco_hydro_2 PF00703.21 AJA92891.1 - 0.11 13.2 0.1 0.26 12.0 0.1 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 CTP_transf_like PF01467.26 AJA92893.1 - 7.6e-14 52.1 0.0 1e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 AJA92893.1 - 0.011 15.6 0.2 0.032 14.1 0.1 1.7 1 1 1 2 2 2 0 FAD synthetase Pantoate_ligase PF02569.15 AJA92893.1 - 0.072 12.3 0.0 6.2 6.0 0.0 2.1 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase Glyco_tran_WecB PF03808.13 AJA92893.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Aldo_ket_red PF00248.21 AJA92894.1 - 5.7e-52 176.7 0.0 6.4e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AIRS PF00586.24 AJA92895.1 - 1.5e-13 51.2 0.0 2.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain SHMT PF00464.19 AJA92896.1 - 5.2e-75 252.5 0.1 7.2e-75 252.1 0.1 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 AJA92896.1 - 6.9e-09 35.4 0.0 1.3e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AJA92896.1 - 2.6e-07 30.1 0.0 6.2e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AJA92896.1 - 8.4e-05 21.7 0.3 0.00018 20.6 0.3 1.7 1 1 0 1 1 1 1 Aminotransferase class-V SelA PF03841.13 AJA92896.1 - 0.00047 19.3 0.0 0.00074 18.6 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase CaMKII_AD PF08332.10 AJA92897.1 - 1.7e-10 41.1 0.2 3.5e-10 40.1 0.2 1.5 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 AJA92897.1 - 2.1e-09 37.7 0.0 3e-09 37.2 0.0 1.2 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AJA92897.1 - 6.6e-09 36.1 0.0 7.4e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 AJA92897.1 - 0.0004 21.0 0.0 0.00047 20.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 AJA92897.1 - 0.001 19.6 0.0 0.0012 19.4 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.6 AJA92897.1 - 0.016 15.3 0.1 0.37 10.9 0.1 2.0 1 1 0 1 1 1 0 SnoaL-like domain DUF3225 PF11533.8 AJA92897.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3225) MRP-L28 PF09812.9 AJA92898.1 - 0.023 14.8 7.5 0.025 14.7 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Dak1 PF02733.17 AJA92898.1 - 0.049 12.5 0.5 0.082 11.8 0.1 1.5 1 1 1 2 2 2 0 Dak1 domain Glycoprotein_G PF00802.19 AJA92898.1 - 0.066 12.6 9.8 0.065 12.6 9.8 1.1 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G AIM3 PF17096.5 AJA92898.1 - 0.2 12.6 8.3 0.23 12.4 8.3 1.1 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DUF87 PF01935.17 AJA92899.1 - 4.8e-38 131.5 0.5 1.4e-37 130.0 0.5 1.8 1 0 0 1 1 1 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 AJA92899.1 - 0.0014 18.1 0.2 0.038 13.4 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF853 PF05872.12 AJA92899.1 - 0.0024 16.5 0.0 0.3 9.6 0.0 2.3 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) HAS-barrel PF09378.10 AJA92899.1 - 0.004 17.3 0.5 0.013 15.6 0.5 1.9 1 0 0 1 1 1 1 HAS barrel domain ABC_tran PF00005.27 AJA92899.1 - 0.021 15.3 0.1 0.053 14.0 0.1 1.8 1 1 0 1 1 1 0 ABC transporter zf-4CXXC_R1 PF10497.9 AJA92901.1 - 0.05 13.8 6.2 0.052 13.8 6.2 1.1 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Zf_RING PF16744.5 AJA92901.1 - 0.11 12.6 5.4 0.13 12.4 5.4 1.1 1 0 0 1 1 1 0 KIAA1045 RING finger DUF2039 PF10217.9 AJA92901.1 - 0.47 10.8 11.9 0.22 11.9 9.7 1.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF2797 PF10977.8 AJA92901.1 - 0.85 9.5 5.9 0.87 9.4 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Rieske PF00355.26 AJA92902.1 - 4.3e-16 58.6 0.0 4.7e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AJA92902.1 - 9.8e-12 44.7 0.0 1.1e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Peptidase_M20 PF01546.28 AJA92903.1 - 2.5e-29 102.5 0.2 4.7e-29 101.6 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AJA92903.1 - 5.4e-15 55.2 1.6 6.2e-14 51.8 0.2 2.2 1 1 1 2 2 2 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 AJA92903.1 - 1.4e-05 24.3 0.7 0.084 11.9 0.0 2.4 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 AJA92903.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 SusF_SusE PF16411.5 AJA92904.1 - 0.05 14.1 0.5 0.76 10.3 0.2 2.1 1 1 1 2 2 2 0 Outer membrane protein SusF_SusE Peptidase_M1_N PF17900.1 AJA92904.1 - 0.056 13.6 0.1 0.078 13.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase M1 N-terminal domain ABC2_membrane_3 PF12698.7 AJA92904.1 - 0.076 12.1 4.0 0.16 11.1 4.0 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Thump_like PF18096.1 AJA92904.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 THUMP domain-like Gram_pos_anchor PF00746.21 AJA92904.1 - 0.23 11.4 4.9 0.88 9.6 1.1 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Saf_2TM PF18303.1 AJA92904.1 - 2 8.0 5.4 2.5 7.7 0.5 2.3 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF4352 PF11611.8 AJA92905.1 - 8e-08 32.6 0.6 1.4e-07 31.8 0.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4352) Chlor_dismutase PF06778.12 AJA92906.1 - 1.8e-55 187.5 0.3 2.3e-55 187.2 0.3 1.0 1 0 0 1 1 1 1 Chlorite dismutase Baculo_PEP_C PF04513.12 AJA92907.1 - 0.0057 16.7 9.7 0.18 11.8 0.9 2.9 2 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 AJA92907.1 - 0.013 15.7 15.5 0.013 15.7 15.5 4.0 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DASH_Duo1 PF08651.10 AJA92907.1 - 0.039 13.7 10.5 0.27 11.1 0.4 3.5 2 2 0 2 2 2 0 DASH complex subunit Duo1 DUF745 PF05335.13 AJA92907.1 - 0.048 13.4 26.5 0.037 13.8 10.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) UPF0184 PF03670.13 AJA92907.1 - 0.11 12.9 3.2 15 6.1 0.2 3.4 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) Virulence_fact PF13769.6 AJA92907.1 - 0.14 12.4 3.9 0.15 12.3 1.0 2.5 2 1 0 2 2 2 0 Virulence factor VWA_2 PF13519.6 AJA92907.1 - 0.28 11.9 6.6 0.3 11.8 1.4 2.8 1 1 1 2 2 2 0 von Willebrand factor type A domain MtrB PF05440.12 AJA92907.1 - 0.31 11.5 2.3 41 4.7 0.1 3.0 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF812 PF05667.11 AJA92907.1 - 1.1 8.1 41.4 1.4 7.7 41.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3300 PF11737.8 AJA92907.1 - 1.2 8.7 6.0 0.58 9.7 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3300) ACP_PD PF04336.12 AJA92907.1 - 1.7 9.1 4.5 2.1 8.8 0.2 2.9 2 2 0 2 2 2 0 Acyl carrier protein phosphodiesterase PSDC PF12588.8 AJA92907.1 - 2.6 8.0 7.5 0.7 9.9 2.4 2.5 2 1 1 3 3 3 0 Phophatidylserine decarboxylase CENP-Q PF13094.6 AJA92907.1 - 2.8 8.1 23.5 0.86 9.8 13.9 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FCH PF00611.23 AJA92907.1 - 2.9 8.3 21.4 3.7 7.9 9.3 4.0 2 2 1 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain Spc7 PF08317.11 AJA92907.1 - 3 6.7 41.1 0.057 12.3 18.7 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF2333 PF10095.9 AJA92907.1 - 3.2 6.7 13.0 0.24 10.3 3.4 2.2 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) Phage_GP20 PF06810.11 AJA92907.1 - 3.4 7.5 36.6 0.19 11.5 7.7 3.4 1 1 2 3 3 3 0 Phage minor structural protein GP20 DegS PF05384.11 AJA92907.1 - 3.7 7.0 29.9 0.22 11.0 10.8 3.2 1 1 2 3 3 3 0 Sensor protein DegS DUF948 PF06103.11 AJA92907.1 - 3.8 7.8 10.0 5.5 7.3 0.5 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MtrG PF04210.13 AJA92907.1 - 3.8 7.4 6.6 1.9 8.4 0.3 3.4 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G AAA_13 PF13166.6 AJA92907.1 - 5.4 5.5 37.0 3.8 6.0 25.7 2.0 1 1 1 2 2 2 0 AAA domain Jnk-SapK_ap_N PF09744.9 AJA92907.1 - 5.5 7.2 33.3 0.63 10.2 12.5 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.9 AJA92907.1 - 6.7 6.1 34.0 7.4 5.9 13.1 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 AJA92907.1 - 9.6 6.2 33.8 2.3 8.3 13.6 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cyclase PF04199.13 AJA92908.1 - 3.8e-36 124.3 0.0 4.7e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase TrmB PF01978.19 AJA92909.1 - 1.9e-21 75.7 0.0 4.1e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 AJA92909.1 - 3.9e-07 29.5 0.0 5.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_IclR PF09339.10 AJA92909.1 - 5.9e-05 22.8 0.0 0.00016 21.4 0.0 1.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AJA92909.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 AJA92909.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Penicillinase_R PF03965.16 AJA92909.1 - 0.0092 16.3 0.0 0.066 13.6 0.0 2.1 2 0 0 2 2 2 1 Penicillinase repressor HTH_27 PF13463.6 AJA92909.1 - 0.013 16.0 0.0 0.033 14.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.20 AJA92909.1 - 0.019 15.3 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator PadR PF03551.14 AJA92909.1 - 0.032 14.2 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PGM_PMM_I PF02878.16 AJA92910.1 - 5.2e-40 136.4 0.0 9.6e-40 135.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AJA92910.1 - 7.6e-25 87.5 0.0 1.7e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AJA92910.1 - 1.1e-20 73.9 0.0 2.7e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AJA92910.1 - 5e-08 33.0 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain CHASE5 PF17149.4 AJA92910.1 - 0.03 14.3 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Periplasmic sensor domain found in signal transduction proteins NADHdh PF00146.21 AJA92911.1 - 4e-95 318.6 16.8 5.8e-95 318.0 16.8 1.2 1 0 0 1 1 1 1 NADH dehydrogenase NDUF_B12 PF08122.12 AJA92911.1 - 0.8 9.8 2.9 1.2 9.2 0.3 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Methyltransf_25 PF13649.6 AJA92912.1 - 2.6e-13 50.5 0.0 4.7e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJA92912.1 - 1.2e-09 38.1 0.0 1.9e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJA92912.1 - 5.8e-08 33.4 0.0 1.1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 AJA92912.1 - 1.1e-06 28.7 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AJA92912.1 - 1.4e-06 27.8 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 AJA92912.1 - 2.1e-06 27.1 0.0 2.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_11 PF08241.12 AJA92912.1 - 4.1e-06 27.4 0.0 8.8e-06 26.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 AJA92912.1 - 0.00014 21.4 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 AJA92912.1 - 0.00014 21.3 0.0 0.0009 18.7 0.0 2.0 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.6 AJA92912.1 - 0.00065 19.6 0.0 0.00097 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 AJA92912.1 - 0.00069 19.0 0.0 0.00096 18.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DREV PF05219.12 AJA92912.1 - 0.0069 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase DOT1 PF08123.13 AJA92912.1 - 0.013 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_PK PF05891.12 AJA92912.1 - 0.065 12.7 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase TPMT PF05724.11 AJA92912.1 - 0.074 12.7 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_16 PF10294.9 AJA92912.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase RST PF12174.8 AJA92912.1 - 0.13 12.2 0.0 0.41 10.6 0.0 1.9 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain TPR_1 PF00515.28 AJA92913.1 - 4.3e-35 118.1 13.3 9.1e-08 31.6 0.1 6.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 AJA92913.1 - 1.9e-31 105.6 6.6 2.8e-06 27.0 0.3 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 AJA92913.1 - 8e-25 87.2 0.0 1.3e-06 28.9 0.1 4.0 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 AJA92913.1 - 9.9e-25 85.1 4.4 0.00017 21.7 0.1 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 AJA92913.1 - 3.7e-24 82.9 7.8 0.00044 20.3 0.4 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 AJA92913.1 - 1.1e-22 79.4 7.3 6.4e-05 22.6 0.0 5.8 3 2 4 7 7 7 4 TPR repeat TPR_14 PF13428.6 AJA92913.1 - 1.2e-21 75.5 0.2 0.0037 17.9 0.0 7.0 1 1 6 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 AJA92913.1 - 1.6e-20 73.4 2.3 9e-07 29.3 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 AJA92913.1 - 6.2e-20 70.4 0.7 0.01 16.4 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 AJA92913.1 - 1.8e-17 63.3 0.1 1.9e-07 31.2 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 AJA92913.1 - 3.1e-17 62.6 1.6 2e-07 31.2 0.5 5.6 2 1 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 AJA92913.1 - 7.4e-13 48.5 0.0 1.6e-06 28.2 0.0 4.1 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 AJA92913.1 - 1.6e-10 40.3 0.0 0.053 13.6 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.8 AJA92913.1 - 3.7e-08 32.7 4.6 0.005 15.8 0.2 3.3 1 1 2 3 3 3 3 NMDA receptor-regulated protein 1 PknG_TPR PF16918.5 AJA92913.1 - 1.4e-07 30.6 0.0 0.00069 18.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase G tetratricopeptide repeat TPR_10 PF13374.6 AJA92913.1 - 1.5e-07 31.0 4.3 0.0004 20.1 0.3 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 AJA92913.1 - 7.6e-06 26.2 3.9 1.4 9.3 0.8 4.5 2 2 3 5 5 5 2 Tetratricopeptide repeat Paf67 PF10255.9 AJA92913.1 - 0.00023 20.3 0.0 0.047 12.7 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase I-associated factor PAF67 TPR_15 PF13429.6 AJA92913.1 - 0.00025 20.3 0.6 0.013 14.8 0.1 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat Thioredoxin_6 PF13848.6 AJA92913.1 - 0.00029 20.8 1.2 0.022 14.7 0.4 3.1 2 2 0 2 2 2 1 Thioredoxin-like domain PPR PF01535.20 AJA92913.1 - 0.001 19.2 7.2 24 5.4 0.0 6.3 7 0 0 7 7 7 0 PPR repeat TPR_21 PF09976.9 AJA92913.1 - 0.0011 18.7 3.2 0.018 14.7 0.4 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat-like domain Coatomer_E PF04733.14 AJA92913.1 - 0.0014 18.2 4.7 0.18 11.2 1.0 2.9 2 1 1 3 3 3 1 Coatomer epsilon subunit DUF3856 PF12968.7 AJA92913.1 - 0.0055 16.8 0.4 12 6.0 0.0 4.1 2 2 2 4 4 4 0 Domain of Unknown Function (DUF3856) Ribosomal_S7 PF00177.21 AJA92913.1 - 0.0066 16.1 1.5 2.2 7.9 0.0 3.4 2 1 1 4 4 4 1 Ribosomal protein S7p/S5e Alkyl_sulf_dimr PF14863.6 AJA92913.1 - 0.023 15.1 2.6 2.3 8.7 0.0 3.1 1 1 0 3 3 3 0 Alkyl sulfatase dimerisation Rapsyn_N PF10579.9 AJA92913.1 - 0.05 13.7 0.1 17 5.6 0.0 3.9 3 2 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region MIT PF04212.18 AJA92913.1 - 0.28 11.3 8.8 3.6 7.7 0.2 5.0 4 2 2 6 6 5 0 MIT (microtubule interacting and transport) domain Proteasome PF00227.26 AJA92914.1 - 2.7e-46 157.5 0.0 3.3e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sec61_beta PF03911.16 AJA92915.1 - 3e-14 52.7 0.3 3.5e-14 52.5 0.3 1.1 1 0 0 1 1 1 1 Sec61beta family Ribosomal_S7 PF00177.21 AJA92916.1 - 1.3e-35 122.3 0.2 2e-35 121.6 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein S7p/S5e ABC_tran PF00005.27 AJA92917.1 - 1.8e-31 109.5 0.0 3.4e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AJA92917.1 - 1.6e-09 38.1 0.0 0.0005 20.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AJA92917.1 - 0.00063 20.2 0.3 0.0066 16.9 0.3 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 AJA92917.1 - 0.0014 18.5 0.0 0.052 13.3 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 AJA92917.1 - 0.0014 18.6 0.1 0.0044 17.0 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain SMC_N PF02463.19 AJA92917.1 - 0.0018 17.7 0.3 0.59 9.5 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AJA92917.1 - 0.0041 17.1 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 AJA92917.1 - 0.0088 16.6 0.2 0.014 15.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AJA92917.1 - 0.0099 15.6 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AJA92917.1 - 0.011 16.0 0.1 0.034 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AJA92917.1 - 0.011 16.1 0.0 0.029 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 AJA92917.1 - 0.011 14.5 0.4 0.75 8.5 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 AJA92917.1 - 0.012 16.0 0.1 0.093 13.1 0.0 2.3 2 1 1 3 3 3 0 RNA helicase AAA_5 PF07728.14 AJA92917.1 - 0.018 15.0 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AJA92917.1 - 0.023 15.3 0.1 0.046 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AJA92917.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 AJA92917.1 - 0.035 14.4 0.0 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AJA92917.1 - 0.039 14.1 0.1 0.048 13.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AJA92917.1 - 0.043 13.6 0.4 0.91 9.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 AJA92917.1 - 0.044 13.5 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 AJA92917.1 - 0.051 12.4 0.0 0.81 8.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein MMR_HSR1 PF01926.23 AJA92917.1 - 0.059 13.4 0.1 0.17 12.0 0.0 1.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 AJA92917.1 - 0.069 13.0 0.1 0.24 11.3 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 AJA92917.1 - 0.087 12.5 0.1 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AJA92917.1 - 0.14 11.7 0.1 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain adh_short_C2 PF13561.6 AJA92918.1 - 4.4e-17 62.4 0.0 7e-16 58.5 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AJA92918.1 - 2.1e-16 60.0 0.0 5.2e-11 42.4 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 AJA92918.1 - 0.0039 16.5 0.0 0.0098 15.2 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 AJA92918.1 - 0.073 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Fer4 PF00037.27 AJA92919.1 - 1.9e-10 40.1 14.2 6.1e-05 22.7 3.0 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJA92919.1 - 2.3e-08 34.5 26.2 4.1e-06 27.3 8.8 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 AJA92919.1 - 4.5e-08 33.9 14.6 6.4e-06 27.0 6.1 2.5 2 1 1 3 3 3 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AJA92919.1 - 5e-08 32.9 14.4 5.5e-07 29.6 4.7 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AJA92919.1 - 4.1e-07 30.4 1.3 0.01 16.3 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJA92919.1 - 1.8e-06 28.0 7.7 1.8e-05 24.8 8.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJA92919.1 - 7.6e-06 26.0 3.7 0.0033 17.5 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AJA92919.1 - 1.8e-05 25.2 0.4 0.11 13.0 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 AJA92919.1 - 0.00016 21.8 4.3 0.00016 21.8 4.3 1.9 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AJA92919.1 - 0.00025 21.0 12.7 0.041 14.0 4.6 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AJA92919.1 - 0.0015 19.0 8.6 0.32 11.6 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 AJA92919.1 - 0.0054 17.6 0.6 3 8.7 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AJA92919.1 - 0.011 16.2 10.5 0.019 15.4 1.0 2.7 3 1 0 3 3 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AJA92919.1 - 0.024 15.5 16.7 0.15 13.0 6.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 AJA92919.1 - 0.061 13.4 14.4 0.079 13.1 3.0 2.7 3 0 0 3 3 2 0 4Fe-4S binding domain Adhesin_P1_N PF18652.1 AJA92919.1 - 0.18 11.8 2.3 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain Fer4_15 PF13459.6 AJA92919.1 - 3.9 8.3 13.5 2.8 8.8 3.6 2.5 1 1 1 2 2 2 0 4Fe-4S single cluster domain 2-Hacid_dh_C PF02826.19 AJA92920.1 - 2.5e-61 206.1 0.0 3.9e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AJA92920.1 - 7.2e-31 106.6 0.1 8.2e-31 106.4 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AJA92920.1 - 0.003 17.7 0.7 0.019 15.1 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase LXG PF04740.12 AJA92920.1 - 0.018 14.7 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily UDPG_MGDP_dh_N PF03721.14 AJA92921.1 - 5.3e-48 163.1 1.2 6e-48 162.9 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AJA92921.1 - 2.2e-35 120.7 1.8 4.8e-35 119.7 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AJA92921.1 - 3.1e-26 91.8 0.7 1.9e-25 89.3 0.5 2.3 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain F420_oxidored PF03807.17 AJA92921.1 - 7.5e-07 29.6 1.9 0.0038 17.8 0.1 4.0 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AJA92921.1 - 3.9e-06 27.1 0.1 0.00022 21.4 0.0 2.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 AJA92921.1 - 0.00072 19.5 0.1 0.0045 16.9 0.0 2.4 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 AJA92921.1 - 0.003 17.8 0.0 0.01 16.1 0.0 2.0 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 AJA92921.1 - 0.0038 16.6 1.9 0.87 8.9 0.1 3.1 2 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar-bind PF04198.13 AJA92921.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain CRAL_TRIO_2 PF13716.6 AJA92921.1 - 0.013 15.7 6.0 0.17 12.1 0.2 2.8 2 1 1 3 3 3 0 Divergent CRAL/TRIO domain Pyr_redox_2 PF07992.14 AJA92921.1 - 0.016 14.4 0.1 0.18 11.0 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 AJA92921.1 - 0.036 14.0 0.6 0.47 10.4 0.1 3.0 3 1 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AAA_17 PF13207.6 AJA92923.1 - 2.5e-14 53.9 0.5 4.2e-14 53.1 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AJA92923.1 - 3.8e-10 40.4 0.1 6.3e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AJA92923.1 - 8e-05 22.6 0.7 0.0012 18.7 0.1 2.5 2 1 1 3 3 3 1 NTPase AAA_28 PF13521.6 AJA92923.1 - 0.00026 21.3 0.1 0.00071 19.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain ADK PF00406.22 AJA92923.1 - 0.00037 20.6 0.4 0.0006 19.9 0.2 1.5 1 1 0 1 1 1 1 Adenylate kinase AAA PF00004.29 AJA92923.1 - 0.00041 20.8 0.3 0.001 19.5 0.3 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 AJA92923.1 - 0.00041 19.4 0.1 0.00089 18.3 0.1 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 AJA92923.1 - 0.00043 20.0 0.0 0.00066 19.4 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain APS_kinase PF01583.20 AJA92923.1 - 0.00066 19.6 0.0 0.0079 16.1 0.0 2.2 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 AJA92923.1 - 0.00098 19.3 0.2 0.0029 17.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AJA92923.1 - 0.012 16.0 0.3 0.025 15.0 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 AJA92923.1 - 0.014 14.6 0.1 0.026 13.7 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 AJA92923.1 - 0.014 15.1 0.1 0.021 14.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AJA92923.1 - 0.018 15.3 0.7 0.078 13.2 0.7 2.0 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AJA92923.1 - 0.018 14.3 0.3 0.048 12.9 0.0 1.8 2 1 1 3 3 3 0 Zeta toxin AAA_14 PF13173.6 AJA92923.1 - 0.026 14.6 0.0 0.084 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 AJA92923.1 - 0.033 13.6 0.8 0.081 12.4 0.1 2.0 2 1 0 2 2 2 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 AJA92923.1 - 0.037 14.1 0.4 0.066 13.3 0.4 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 AJA92923.1 - 0.041 13.6 0.1 0.059 13.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AJA92923.1 - 0.053 13.5 0.7 0.26 11.3 0.6 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 AJA92923.1 - 0.072 13.0 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 CoaE PF01121.20 AJA92923.1 - 0.078 12.6 0.3 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_25 PF13481.6 AJA92923.1 - 0.095 12.3 0.6 5.4 6.5 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AJA92923.1 - 0.096 12.4 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 AJA92923.1 - 0.096 12.4 0.1 0.16 11.7 0.1 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 AJA92923.1 - 0.17 11.8 0.1 0.93 9.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Cu-oxidase_3 PF07732.15 AJA92924.1 - 2.7e-05 24.2 0.2 9.1e-05 22.5 0.2 1.9 1 0 0 1 1 1 1 Multicopper oxidase BPD_transp_1 PF00528.22 AJA92927.1 - 4.9e-40 137.2 17.2 4.9e-40 137.2 17.2 1.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component MerE PF05052.12 AJA92927.1 - 0.46 10.5 3.4 7.3 6.6 0.0 2.8 3 0 0 3 3 3 0 MerE protein FtsX PF02687.21 AJA92927.1 - 5.1 7.6 23.4 0.15 12.6 5.6 3.1 3 0 0 3 3 3 0 FtsX-like permease family MarR PF01047.22 AJA92928.1 - 0.0036 17.2 0.2 0.0079 16.1 0.2 1.6 1 0 0 1 1 1 1 MarR family B-block_TFIIIC PF04182.12 AJA92928.1 - 0.004 17.3 0.2 0.0078 16.4 0.2 1.5 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC CDC27 PF09507.10 AJA92928.1 - 0.11 11.8 42.1 0.13 11.6 42.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RPA_C PF08784.11 AJA92928.1 - 0.79 10.4 2.9 5.8 7.6 2.9 2.2 1 1 0 1 1 1 0 Replication protein A C terminal PARM PF17061.5 AJA92928.1 - 1.3 9.1 7.3 1.6 8.8 7.3 1.1 1 0 0 1 1 1 0 PARM DUF3558 PF12079.8 AJA92928.1 - 2.2 8.2 6.0 22 5.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3558) SOBP PF15279.6 AJA92928.1 - 3.7 8.1 14.8 4.8 7.7 14.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.9 AJA92928.1 - 6.8 4.8 19.1 8.3 4.5 19.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 AJA92928.1 - 7.6 5.1 16.5 8.6 4.9 16.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aminotran_1_2 PF00155.21 AJA92929.1 - 8.1e-49 166.7 0.0 9.5e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AJA92929.1 - 0.0003 19.4 0.1 0.00047 18.8 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AJA92929.1 - 0.0023 17.3 0.3 0.012 14.9 0.3 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AJA92929.1 - 0.0055 15.7 0.6 0.0091 15.0 0.6 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Epimerase PF01370.21 AJA92930.1 - 2.2e-58 197.6 0.0 2.6e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJA92930.1 - 8.2e-54 183.2 0.6 4.5e-53 180.8 0.6 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AJA92930.1 - 6.7e-27 94.2 0.2 9.8e-27 93.7 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AJA92930.1 - 1.2e-21 77.1 0.1 6.3e-21 74.8 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AJA92930.1 - 3.6e-21 75.5 0.0 3.9e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AJA92930.1 - 1.9e-14 53.5 0.1 3e-09 36.5 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein KR PF08659.10 AJA92930.1 - 6.4e-08 32.7 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AJA92930.1 - 7.3e-07 29.3 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 AJA92930.1 - 2.8e-05 24.4 0.1 5.1e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 AJA92930.1 - 0.00024 20.6 0.0 0.00041 19.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 AJA92930.1 - 0.0019 17.8 0.1 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 AJA92930.1 - 0.014 15.5 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 AJA92930.1 - 0.022 14.3 0.1 0.043 13.4 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 AJA92930.1 - 0.039 14.2 0.1 0.2 12.0 0.0 2.2 3 0 0 3 3 3 0 TrkA-N domain 3HCDH_N PF02737.18 AJA92930.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4369 PF14289.6 AJA92931.1 - 0.063 13.8 0.6 0.12 12.9 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) SGS PF05002.15 AJA92931.1 - 0.17 12.0 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 SGS domain HNH_5 PF14279.6 AJA92932.1 - 0.00099 18.9 0.2 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 HNH endonuclease Prim_Zn_Ribbon PF08273.12 AJA92932.1 - 0.011 16.1 1.0 0.17 12.2 0.1 2.7 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase A2L_zn_ribbon PF08792.10 AJA92932.1 - 0.025 14.3 3.1 0.16 11.7 0.2 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Gin PF10764.9 AJA92932.1 - 0.025 14.5 0.8 0.13 12.2 0.2 2.1 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin Zn_ribbon_SprT PF17283.2 AJA92932.1 - 0.03 14.2 0.1 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain SAP30_Sin3_bdg PF13867.6 AJA92932.1 - 0.032 14.6 0.0 0.045 14.1 0.0 1.3 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 zf_UBZ PF18439.1 AJA92932.1 - 0.044 13.4 2.6 0.73 9.5 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-LITAF-like PF10601.9 AJA92932.1 - 0.055 13.7 1.0 10 6.4 0.1 2.2 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain TF_Zn_Ribbon PF08271.12 AJA92932.1 - 0.11 12.0 1.0 0.71 9.4 1.0 2.1 1 1 0 1 1 1 0 TFIIB zinc-binding SR1P PF13790.6 AJA92932.1 - 0.24 11.6 2.4 0.4 10.8 0.2 2.1 2 0 0 2 2 2 0 SR1 protein zf-RRN7 PF11781.8 AJA92932.1 - 0.34 10.6 3.0 1.6 8.5 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DegT_DnrJ_EryC1 PF01041.17 AJA92933.1 - 2.9e-121 405.2 0.0 3.3e-121 405.0 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AJA92933.1 - 9.8e-11 41.4 0.2 1.7e-10 40.6 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AJA92933.1 - 2.8e-06 26.6 0.4 5.7e-06 25.5 0.4 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AJA92933.1 - 2.5e-05 23.0 0.6 3.8e-05 22.4 0.6 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Surfac_D-trimer PF09006.11 AJA92933.1 - 0.021 14.7 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation DUF1967 PF09269.11 AJA92933.1 - 0.034 14.1 0.1 0.95 9.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) Auto_anti-p27 PF06677.12 AJA92934.1 - 2.5e-10 40.4 1.7 3.7e-10 39.8 1.7 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.12 AJA92934.1 - 0.072 12.6 2.0 0.14 11.7 2.0 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 AJA92934.1 - 0.47 9.9 4.9 1.8 8.1 4.7 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 AJA92934.1 - 0.9 9.9 3.6 16 5.9 0.0 2.3 1 1 1 2 2 2 0 zinc-ribbon SBDS PF01172.18 AJA92936.1 - 1.3e-20 73.2 0.7 2.5e-20 72.3 0.7 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 AJA92936.1 - 1.7e-16 60.2 0.5 2.6e-16 59.7 0.1 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain EFG_C PF00679.24 AJA92936.1 - 0.007 16.4 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Big_3_2 PF12245.8 AJA92936.1 - 0.042 14.1 0.0 10 6.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain Radical_SAM PF04055.21 AJA92938.1 - 0.00018 21.9 0.1 0.011 16.1 0.1 2.3 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 AJA92938.1 - 0.0028 17.9 0.0 0.0058 16.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AJA92938.1 - 0.0084 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain EMC3_TMCO1 PF01956.16 AJA92940.1 - 2.7e-14 53.3 12.2 7.3e-14 51.9 12.2 1.6 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Orf78 PF06024.12 AJA92940.1 - 0.12 12.6 0.4 0.18 12.1 0.4 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Ets PF00178.22 AJA92940.1 - 0.16 12.4 1.5 0.28 11.7 1.5 1.4 1 0 0 1 1 1 0 Ets-domain Phage_HK97_TLTM PF06120.11 AJA92941.1 - 0.035 13.3 0.3 0.086 12.0 0.2 1.6 1 1 1 2 2 2 0 Tail length tape measure protein Coiled-coil_56 PF09813.9 AJA92941.1 - 0.093 12.8 0.2 0.25 11.4 0.1 1.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 56 EMC3_TMCO1 PF01956.16 AJA92941.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PAP2 PF01569.21 AJA92943.1 - 9.4e-24 83.7 1.1 1.5e-23 83.1 1.1 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 AJA92943.1 - 3.9e-12 46.2 5.3 1.1e-11 44.8 5.3 1.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 AJA92943.1 - 7.5e-06 26.4 0.8 7.5e-06 26.4 0.8 2.0 2 0 0 2 2 2 1 PAP2 superfamily C-terminal DUF1097 PF06496.11 AJA92943.1 - 0.017 15.2 1.6 0.16 12.0 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) OppC_N PF12911.7 AJA92943.1 - 1.4 8.9 0.0 1.4 8.9 0.0 2.8 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C DUF2198 PF09964.9 AJA92943.1 - 2 8.6 6.6 0.74 9.9 3.4 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) RibD_C PF01872.17 AJA92945.1 - 3.4e-48 164.1 0.2 3.8e-48 164.0 0.2 1.0 1 0 0 1 1 1 1 RibD C-terminal domain DUF2067 PF09840.9 AJA92945.1 - 0.018 14.6 0.3 0.027 14.0 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Semenogelin PF05474.11 AJA92945.1 - 0.056 12.0 0.0 0.07 11.7 0.0 1.1 1 0 0 1 1 1 0 Semenogelin Polyketide_cyc2 PF10604.9 AJA92947.1 - 3.6e-09 37.0 0.0 4.1e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AJA92947.1 - 2.6e-07 30.9 0.0 6.2e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport GHMP_kinases_N PF00288.26 AJA92948.1 - 1.2e-09 38.2 0.5 2.2e-09 37.4 0.5 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain SASP PF00269.20 AJA92948.1 - 0.095 12.7 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type HMMR_N PF15905.5 AJA92949.1 - 0.0001 21.9 7.5 0.00013 21.6 7.5 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 AJA92949.1 - 0.00013 21.0 6.8 0.00016 20.7 6.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 AJA92949.1 - 0.00025 21.2 12.0 0.00085 19.5 9.0 2.0 1 1 1 2 2 2 1 Tropomyosin like AAA_13 PF13166.6 AJA92949.1 - 0.0003 19.6 4.2 0.00037 19.3 4.2 1.0 1 0 0 1 1 1 1 AAA domain DUF3450 PF11932.8 AJA92949.1 - 0.00068 19.0 1.5 0.00086 18.7 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF16 PF01519.16 AJA92949.1 - 0.0012 19.3 4.0 0.08 13.4 2.6 2.2 1 1 1 2 2 2 2 Protein of unknown function DUF16 DUF1664 PF07889.12 AJA92949.1 - 0.0016 18.5 4.8 0.028 14.4 1.7 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) ATG16 PF08614.11 AJA92949.1 - 0.0087 16.3 1.0 0.011 15.9 1.0 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Atg14 PF10186.9 AJA92949.1 - 0.019 14.1 1.8 0.022 13.9 1.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 AJA92949.1 - 0.024 14.5 5.8 0.039 13.8 5.7 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FemAB PF02388.16 AJA92949.1 - 0.026 13.4 1.8 0.032 13.1 1.8 1.2 1 0 0 1 1 1 0 FemAB family CENP-Q PF13094.6 AJA92949.1 - 0.026 14.7 1.7 0.039 14.1 1.7 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF724 PF05266.14 AJA92949.1 - 0.034 14.0 7.3 0.068 13.0 7.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Spectrin PF00435.21 AJA92949.1 - 0.083 13.4 2.8 0.18 12.3 2.9 1.6 1 1 0 1 1 1 0 Spectrin repeat OmpH PF03938.14 AJA92949.1 - 0.087 13.2 3.0 0.15 12.4 3.0 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Prefoldin PF02996.17 AJA92949.1 - 0.096 12.6 4.2 1 9.3 3.2 2.3 1 1 1 2 2 2 0 Prefoldin subunit GAS PF13851.6 AJA92949.1 - 0.097 12.0 6.7 0.094 12.1 5.3 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3552 PF12072.8 AJA92949.1 - 0.097 12.1 7.9 0.19 11.2 7.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) FadA PF09403.10 AJA92949.1 - 0.12 12.8 6.0 1.8 9.1 2.5 2.7 1 1 1 2 2 2 0 Adhesion protein FadA TMPIT PF07851.13 AJA92949.1 - 0.31 10.2 2.0 0.41 9.8 2.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein MIP-T3_C PF17749.1 AJA92949.1 - 0.34 10.9 7.1 2 8.4 2.6 2.4 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Mei5 PF10376.9 AJA92949.1 - 0.36 10.6 7.5 0.69 9.7 7.0 1.9 1 1 0 1 1 1 0 Double-strand recombination repair protein Fib_alpha PF08702.10 AJA92949.1 - 0.37 11.0 4.6 2.6 8.2 4.3 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 AJA92949.1 - 0.43 9.9 3.1 0.49 9.7 3.1 1.2 1 0 0 1 1 1 0 FAM76 protein Nas2_N PF18265.1 AJA92949.1 - 0.78 9.7 8.3 15 5.6 0.1 3.2 2 1 1 3 3 3 0 Nas2 N_terminal domain FlaC_arch PF05377.11 AJA92949.1 - 0.82 10.1 9.6 5.9 7.4 3.1 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 AJA92949.1 - 0.87 9.7 6.4 1.6 8.8 6.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 AJA92949.1 - 0.94 10.2 4.0 3.8 8.2 4.0 1.9 1 1 0 1 1 1 0 Initiation control protein YabA XhlA PF10779.9 AJA92949.1 - 2 8.7 8.8 5.5 7.3 3.1 2.3 1 1 0 2 2 2 0 Haemolysin XhlA DivIC PF04977.15 AJA92949.1 - 6.2 6.7 7.1 12 5.7 5.5 2.2 1 1 0 1 1 1 0 Septum formation initiator ABC_tran_CTD PF16326.5 AJA92949.1 - 7 7.0 10.3 3.1 8.1 5.4 2.5 2 1 1 3 3 3 0 ABC transporter C-terminal domain His_biosynth PF00977.21 AJA92950.1 - 2e-83 279.3 0.9 2.4e-83 279.1 0.9 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AJA92950.1 - 1.6e-07 30.8 0.1 9.3e-05 21.7 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 AJA92950.1 - 1.2e-05 24.9 0.1 0.03 13.7 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.14 AJA92950.1 - 7.7e-05 22.1 0.4 0.033 13.5 0.0 2.4 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 AJA92950.1 - 0.0011 18.3 0.1 0.28 10.5 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase Trp_syntA PF00290.20 AJA92950.1 - 0.0027 16.6 0.1 0.0045 15.9 0.1 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain DHO_dh PF01180.21 AJA92950.1 - 0.0084 15.3 0.1 0.35 10.0 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase PcrB PF01884.17 AJA92950.1 - 0.023 14.2 0.2 0.051 13.0 0.1 1.6 2 0 0 2 2 2 0 PcrB family G3P_antiterm PF04309.12 AJA92950.1 - 0.027 13.9 0.7 1.3 8.5 0.1 2.5 2 1 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Rieske PF00355.26 AJA92951.1 - 8.2e-07 28.9 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Oxidored_q2 PF00420.24 AJA92952.1 - 2.1e-21 75.5 4.8 2.7e-21 75.1 4.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DoxX PF07681.12 AJA92952.1 - 0.045 14.3 2.6 0.059 14.0 2.6 1.2 1 0 0 1 1 1 0 DoxX DUF5423 PF17461.2 AJA92952.1 - 0.21 10.4 0.4 0.22 10.3 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) DUF3165 PF11364.8 AJA92952.1 - 0.37 11.2 3.6 10 6.6 3.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3165) Pcc1 PF09341.10 AJA92953.1 - 7.6e-09 35.6 0.0 8.4e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Ribosomal_S17 PF00366.20 AJA92954.1 - 1.2e-18 66.9 1.9 2.1e-18 66.1 1.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 AJA92954.1 - 0.0046 17.3 0.5 0.0085 16.5 0.1 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Pribosyltran PF00156.27 AJA92955.1 - 1.6e-14 53.7 0.1 2e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AJA92955.1 - 0.0078 15.7 0.0 0.0096 15.4 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase tRNA-synt_2 PF00152.20 AJA92956.1 - 8.3e-80 268.2 0.0 1e-79 267.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AJA92956.1 - 2e-10 40.5 1.1 3.7e-10 39.7 0.5 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AJA92956.1 - 0.081 12.4 0.1 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DraK_HK_N PF18092.1 AJA92956.1 - 0.1 13.0 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 DraK Histidine Kinase N-terminal domain PurL_C PF16904.5 AJA92957.1 - 0.074 13.4 1.7 13 6.1 0.1 2.8 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine synthase II C-terminus Aminotran_1_2 PF00155.21 AJA92959.1 - 3.1e-43 148.3 0.0 3.7e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AJA92959.1 - 3.2e-05 23.0 0.0 4.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Allinase UbiD PF01977.16 AJA92960.1 - 2.4e-146 487.7 0.2 2.9e-146 487.5 0.2 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HTH_23 PF13384.6 AJA92961.1 - 0.00011 21.8 0.0 0.00046 19.9 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_11 PF08279.12 AJA92961.1 - 0.00055 19.8 0.1 0.0015 18.5 0.1 1.8 1 0 0 1 1 1 1 HTH domain B12-binding_2 PF02607.17 AJA92961.1 - 0.00057 20.3 0.0 0.00093 19.6 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain HTH_24 PF13412.6 AJA92961.1 - 0.00076 19.0 0.1 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Mga PF08280.11 AJA92961.1 - 0.0018 18.2 0.1 0.4 10.7 0.0 3.0 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_Crp_2 PF13545.6 AJA92961.1 - 0.0031 17.5 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 AJA92961.1 - 0.031 14.2 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 MarR family Mnd1 PF03962.15 AJA92961.1 - 0.051 13.9 0.6 1.9 8.9 0.0 3.0 3 0 0 3 3 3 0 Mnd1 HTH domain HTH_29 PF13551.6 AJA92961.1 - 0.052 13.6 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix PAX PF00292.18 AJA92961.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain HTH_10 PF04967.12 AJA92961.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain NAD_synthase PF02540.17 AJA92962.1 - 7.8e-75 251.1 0.1 9e-75 250.9 0.1 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 AJA92962.1 - 1.6e-05 23.9 0.0 0.0046 15.8 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 AJA92962.1 - 0.0013 18.3 0.0 0.0061 16.1 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AJA92962.1 - 0.0083 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase HTH_25 PF13413.6 AJA92962.1 - 0.016 15.1 0.5 11 5.9 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain ATP_bind_3 PF01171.20 AJA92962.1 - 0.021 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 PP-loop family ThiI PF02568.14 AJA92962.1 - 0.069 12.7 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Oxidored_q4 PF00507.19 AJA92964.1 - 1.1e-18 67.3 0.7 1.3e-18 66.9 0.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 MPS-4 PF17523.2 AJA92964.1 - 0.04 14.0 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Gram_pos_anchor PF00746.21 AJA92964.1 - 0.54 10.2 0.1 0.54 10.2 0.1 2.1 3 0 0 3 3 3 0 LPXTG cell wall anchor motif PGM_PMM_I PF02878.16 AJA92965.1 - 1.1e-23 83.5 0.0 2.8e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AJA92965.1 - 5.7e-16 58.7 0.2 2.2e-15 56.8 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AJA92965.1 - 1.2e-11 45.1 0.0 2.5e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AJA92965.1 - 3.8e-06 27.0 0.0 7.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PELOTA_1 PF15608.6 AJA92965.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 PELOTA RNA binding domain SirA PF10747.9 AJA92965.1 - 0.32 11.3 2.9 0.66 10.3 2.9 1.5 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA AhpC-TSA PF00578.21 AJA92966.1 - 5.4e-22 78.0 0.2 6.9e-22 77.7 0.2 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJA92966.1 - 3.6e-15 56.0 0.1 4.6e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 AJA92966.1 - 1.8e-05 25.0 0.1 3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AJA92966.1 - 0.0003 21.2 0.1 0.0005 20.5 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain GSHPx PF00255.19 AJA92966.1 - 0.0089 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase Thioredoxin PF00085.20 AJA92966.1 - 0.026 14.5 0.2 0.31 11.0 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.6 AJA92966.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 F plasmid transfer operon protein SCO1-SenC PF02630.14 AJA92966.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC T4_deiodinase PF00837.17 AJA92966.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase tRNA_int_endo PF01974.17 AJA92967.1 - 1.4e-30 105.2 0.1 2.9e-30 104.2 0.0 1.5 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 AJA92967.1 - 1.7e-16 59.6 0.1 2.7e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain AIPR PF10592.9 AJA92968.1 - 1.3e-47 162.9 10.4 1.3e-47 162.9 10.4 1.8 2 0 0 2 2 2 1 AIPR protein MFS_1 PF07690.16 AJA92970.1 - 0.00076 18.5 2.8 0.001 18.1 2.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2955 PF11168.8 AJA92970.1 - 0.15 11.9 4.3 0.068 13.0 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) DUF3098 PF11297.8 AJA92970.1 - 0.52 9.9 9.7 0.57 9.8 0.9 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3098) Monooxygenase_B PF04744.12 AJA92971.1 - 5.2e-09 35.4 1.1 2.7e-08 33.1 0.2 2.3 1 1 1 2 2 2 1 Monooxygenase subunit B protein tRNA_NucTransf2 PF09249.11 AJA92973.1 - 4.9e-35 120.2 0.1 1e-34 119.2 0.1 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain NTP_transf_2 PF01909.23 AJA92973.1 - 2.7e-12 46.8 0.3 7.8e-12 45.3 0.3 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AJA92973.1 - 0.0002 21.3 0.6 0.00085 19.4 0.1 2.2 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase SMODS PF18144.1 AJA92973.1 - 0.00038 20.7 0.6 0.001 19.3 0.6 1.7 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain DNA_pol_B_palm PF14792.6 AJA92973.1 - 0.088 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm Asparaginase_2 PF01112.18 AJA92973.1 - 0.13 11.3 0.1 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Asparaginase HIT PF01230.23 AJA92974.1 - 2.3e-07 31.5 0.0 0.0057 17.4 0.0 2.3 2 0 0 2 2 2 2 HIT domain GalP_UDP_transf PF01087.22 AJA92974.1 - 3.3e-05 24.4 0.1 7.3e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 AJA92974.1 - 0.00031 20.5 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.8 AJA92974.1 - 0.0026 18.2 0.0 0.12 12.8 0.0 2.3 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Aldo_ket_red PF00248.21 AJA92975.1 - 8.3e-26 90.9 0.2 7e-22 78.0 0.1 2.5 1 1 1 2 2 2 2 Aldo/keto reductase family Aconitase PF00330.20 AJA92976.1 - 3.7e-149 497.7 0.0 4.1e-149 497.5 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 AJA92976.1 - 0.0055 15.5 0.0 0.0079 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) THUMP PF02926.17 AJA92976.1 - 0.14 12.3 0.0 0.85 9.7 0.0 2.0 2 0 0 2 2 2 0 THUMP domain Fer2_3 PF13085.6 AJA92977.1 - 1.7e-30 105.2 0.1 3.6e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 AJA92977.1 - 1.6e-11 44.4 2.7 1.6e-11 44.4 2.7 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJA92977.1 - 2.5e-10 40.3 2.9 2.5e-10 40.3 2.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AJA92977.1 - 1.9e-08 34.8 3.4 1.9e-08 34.8 3.4 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJA92977.1 - 6.2e-08 32.7 5.6 1e-07 32.0 2.7 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AJA92977.1 - 7.2e-08 33.3 3.2 7.2e-08 33.3 3.2 2.1 2 0 0 2 2 1 1 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AJA92977.1 - 5.8e-07 30.0 4.1 5.8e-07 30.0 4.1 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AJA92977.1 - 1.3e-05 24.8 0.8 1.3e-05 24.8 0.8 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer2 PF00111.27 AJA92977.1 - 4.1e-05 23.4 1.0 7.6e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 AJA92977.1 - 0.00014 22.0 6.2 0.08 13.1 0.1 2.8 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AJA92977.1 - 0.002 18.2 1.8 0.002 18.2 1.8 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_2 PF12797.7 AJA92977.1 - 0.024 14.7 1.8 0.024 14.7 1.8 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_4 PF12800.7 AJA92977.1 - 0.11 13.0 1.3 0.11 13.0 1.3 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain NADH_4Fe-4S PF10589.9 AJA92977.1 - 0.32 11.1 3.0 12 6.0 0.7 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Fer4_21 PF14697.6 AJA92977.1 - 0.35 11.0 14.5 0.03 14.4 6.8 2.8 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AJA92977.1 - 0.97 10.5 21.4 0.39 11.8 4.6 3.2 3 1 0 3 3 3 0 4Fe-4S binding domain tRNA-synt_1 PF00133.22 AJA92978.1 - 1e-133 446.8 6.0 1.5e-133 446.2 6.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AJA92978.1 - 4e-29 101.6 2.0 1.2e-28 100.0 2.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AJA92978.1 - 8.6e-25 87.3 2.0 8.3e-10 38.0 0.1 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AJA92978.1 - 2.1e-07 30.6 0.0 1.5e-05 24.5 0.0 2.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AJA92978.1 - 7.8e-06 25.0 0.0 6.8e-05 21.9 0.1 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) DHHA1 PF02272.19 AJA92979.1 - 1.4e-10 41.7 0.0 4.2e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 AJA92979.1 - 0.0066 16.7 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 DHH family TMEMspv1-c74-12 PF11044.8 AJA92982.1 - 0.0076 16.2 3.5 0.018 15.0 3.5 1.6 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein PPC PF04151.15 AJA92982.1 - 0.024 15.7 0.1 0.09 13.9 0.1 2.0 1 1 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain NurA PF09376.10 AJA92983.1 - 3.9e-19 69.3 0.3 1.1e-18 67.8 0.1 1.8 2 1 0 2 2 2 1 NurA domain DUF2608 PF11019.8 AJA92983.1 - 0.015 14.8 0.1 0.02 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Copper-bind PF00127.20 AJA92984.1 - 2.2e-06 28.0 0.0 6.2e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJA92984.1 - 0.00078 19.5 0.0 0.0023 18.0 0.0 1.7 2 0 0 2 2 2 1 Cupredoxin-like domain zf-C2H2 PF00096.26 AJA92985.1 - 6.1e-11 42.1 4.4 8.7e-05 22.8 0.2 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 AJA92985.1 - 3.3e-09 36.8 3.8 0.00027 21.5 0.4 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 AJA92985.1 - 3.4e-07 30.4 3.0 0.0078 16.5 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 AJA92985.1 - 4.3e-07 29.6 0.4 0.00033 20.3 0.0 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 AJA92985.1 - 6.7e-06 26.0 6.2 0.015 15.3 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 AJA92985.1 - 4.5e-05 23.7 1.8 0.056 13.8 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.15 AJA92985.1 - 5.9e-05 23.0 2.8 0.0044 17.0 0.8 2.3 1 1 1 2 2 2 1 BED zinc finger DUF629 PF04780.12 AJA92985.1 - 7.8e-05 21.4 5.3 0.023 13.3 0.5 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF629) Actin_micro PF17003.5 AJA92985.1 - 0.00016 21.0 6.8 0.011 14.9 0.7 2.0 1 1 1 2 2 2 2 Putative actin-like family zf_ZIC PF18366.1 AJA92985.1 - 0.00022 21.3 1.2 0.19 11.9 0.1 2.1 2 0 0 2 2 2 2 Zic proteins zinc finger domain zf_UBZ PF18439.1 AJA92985.1 - 0.00045 19.7 3.4 0.38 10.4 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 AJA92985.1 - 0.00052 20.3 6.8 0.059 13.7 1.2 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 AJA92985.1 - 0.00056 20.6 0.8 1 10.0 0.0 2.0 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 AJA92985.1 - 0.0019 18.4 1.3 0.39 11.1 0.1 2.0 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 AJA92985.1 - 0.0023 18.3 11.7 0.0028 18.0 0.1 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2HE PF16278.5 AJA92985.1 - 0.0024 18.3 7.8 0.0093 16.4 7.8 1.8 1 1 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_aberr PF17017.5 AJA92985.1 - 0.0088 16.2 4.1 0.019 15.1 4.1 1.5 1 1 0 1 1 1 1 Aberrant zinc-finger FOXP-CC PF16159.5 AJA92985.1 - 0.0099 16.5 3.1 2.4 8.8 0.3 2.1 2 0 0 2 2 2 2 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 AJA92985.1 - 0.012 15.2 0.9 4 7.1 0.1 2.1 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 AJA92985.1 - 0.016 15.5 4.6 0.033 14.5 4.4 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 AJA92985.1 - 0.046 13.9 2.7 0.69 10.1 0.1 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger zinc_ribbon_5 PF13719.6 AJA92985.1 - 0.061 13.1 0.9 0.61 9.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 AJA92985.1 - 0.07 13.0 0.7 3.1 7.7 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 AJA92985.1 - 0.13 12.4 5.9 0.14 12.3 0.5 2.1 1 1 1 2 2 2 0 Zinc ribbon domain Evr1_Alr PF04777.13 AJA92985.1 - 0.14 12.7 4.4 0.31 11.6 0.8 2.0 1 1 1 2 2 2 0 Erv1 / Alr family OrsD PF12013.8 AJA92985.1 - 0.14 12.6 2.7 2.4 8.7 0.2 2.0 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D YhfH PF14149.6 AJA92985.1 - 0.18 11.8 5.6 0.21 11.6 0.2 2.4 2 0 0 2 2 2 0 YhfH-like protein DUF983 PF06170.12 AJA92985.1 - 0.18 12.2 0.6 8.4 6.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) PDDEXK_1 PF12705.7 AJA92986.1 - 1.1e-07 32.0 0.0 1.8e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Dna2 PF08696.11 AJA92986.1 - 0.0047 16.7 0.1 0.23 11.3 0.0 2.2 1 1 1 2 2 2 1 DNA replication factor Dna2 DciA PF05258.12 AJA92986.1 - 0.019 15.3 0.0 0.4 11.1 0.0 2.4 2 0 0 2 2 2 0 Dna[CI] antecedent, DciA DUF1281_C PF18406.1 AJA92986.1 - 0.12 12.1 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Ferredoxin-like domain in Api92-like protein Proton_antipo_M PF00361.20 AJA92987.1 - 1.7e-67 227.7 23.3 1.7e-67 227.7 23.3 2.5 1 1 1 2 2 2 1 Proton-conducting membrane transporter Thioredoxin PF00085.20 AJA92989.1 - 1.3e-29 102.2 0.0 1.5e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AJA92989.1 - 5.4e-10 39.5 0.1 1.9e-06 28.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 AJA92989.1 - 6.5e-09 36.2 0.1 1.3e-08 35.3 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AJA92989.1 - 5.5e-06 26.5 0.1 8.3e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 AJA92989.1 - 5.7e-06 26.3 0.0 6.8e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJA92989.1 - 8.5e-05 22.3 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_3 PF13192.6 AJA92989.1 - 0.00021 21.3 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 AJA92989.1 - 0.00028 20.7 0.0 0.00031 20.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 AJA92989.1 - 0.0013 18.1 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 AJA92989.1 - 0.0014 18.5 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.11 AJA92989.1 - 0.0086 16.0 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE DUF953 PF06110.11 AJA92989.1 - 0.024 14.3 0.2 0.066 12.8 0.2 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_6 PF13848.6 AJA92989.1 - 0.025 14.5 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.24 AJA92989.1 - 0.065 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Ribosomal_L7Ae PF01248.26 AJA92990.1 - 1.5e-10 40.7 0.4 1.7e-10 40.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Trans_coact PF16805.5 AJA92990.1 - 0.011 15.8 1.8 2.3 8.4 0.1 2.2 2 0 0 2 2 2 0 Phage late-transcription coactivator DEAD PF00270.29 AJA92991.1 - 1.9e-49 167.8 0.2 6.3e-48 162.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AJA92991.1 - 2.5e-28 98.6 0.8 1.3e-27 96.3 0.4 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AJA92991.1 - 2.3e-05 24.4 0.0 6.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 AJA92991.1 - 0.00014 21.2 0.3 0.00019 20.7 0.3 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 AJA92991.1 - 0.00038 19.9 0.2 0.0036 16.7 0.0 2.3 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 AJA92991.1 - 0.0055 16.4 0.1 0.014 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 AJA92991.1 - 0.012 15.4 0.1 0.036 13.9 0.0 1.7 2 0 0 2 2 2 0 Helicase SecA_DEAD PF07517.14 AJA92991.1 - 0.074 12.3 0.2 0.14 11.4 0.2 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain DUF4839 PF16127.5 AJA92991.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4839) AAA_19 PF13245.6 AJA92991.1 - 0.14 12.5 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain CBS PF00571.28 AJA92992.1 - 4.9e-26 90.9 0.5 5.1e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 CBS domain DUF2920 PF11144.8 AJA92993.1 - 0.12 11.6 0.1 0.13 11.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Beach PF02138.18 AJA92994.1 - 0.02 14.3 0.2 0.029 13.8 0.2 1.3 1 1 0 1 1 1 0 Beige/BEACH domain DUF2408 PF10303.9 AJA92994.1 - 0.05 14.2 0.7 0.069 13.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF2203 PF09969.9 AJA92995.1 - 6.3e-37 127.0 0.5 7.1e-37 126.8 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) CbiC PF02570.15 AJA92996.1 - 2.7e-73 245.8 0.1 3e-73 245.7 0.1 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase tRNA-Thr_ED PF08915.11 AJA92998.1 - 1.6e-42 144.8 0.0 3.8e-42 143.6 0.0 1.7 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase HGTP_anticodon PF03129.20 AJA92998.1 - 7.4e-24 83.7 1.0 1.6e-23 82.7 1.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AJA92998.1 - 9.1e-17 61.6 0.1 2.3e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FeoB_associated PF12669.7 AJA92999.1 - 0.054 13.9 1.1 3.3 8.2 0.1 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Voltage_CLC PF00654.20 AJA92999.1 - 0.096 11.9 1.0 0.12 11.6 1.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel Retrotrans_gag PF03732.17 AJA92999.1 - 0.17 12.2 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein BRF1 PF07741.13 AJA93000.1 - 0.049 14.0 0.0 0.068 13.5 0.0 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4539 PF15072.6 AJA93000.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Glycos_transf_4 PF00953.21 AJA93001.1 - 1.5e-27 96.5 16.2 1.5e-27 96.5 16.2 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 4 DUF2254 PF10011.9 AJA93001.1 - 0.94 8.2 5.7 0.12 11.2 0.9 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) SPC25 PF06703.11 AJA93001.1 - 1 9.2 4.6 2.2 8.1 0.2 2.7 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) TruD PF01142.18 AJA93002.1 - 3.2e-79 266.7 0.1 1.2e-78 264.9 0.1 1.7 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Flavoprotein PF02441.19 AJA93003.1 - 1.8e-27 96.1 0.7 2.1e-27 95.8 0.7 1.0 1 0 0 1 1 1 1 Flavoprotein Y_phosphatase PF00102.27 AJA93003.1 - 0.034 13.7 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF2730 PF10805.8 AJA93004.1 - 0.052 13.6 1.8 0.25 11.5 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) CLN3 PF02487.17 AJA93004.1 - 0.058 12.4 0.0 0.069 12.2 0.0 1.0 1 0 0 1 1 1 0 CLN3 protein TipE PF16972.5 AJA93004.1 - 0.073 12.2 0.4 0.089 12.0 0.4 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE DUF2254 PF10011.9 AJA93004.1 - 0.12 11.1 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) TPP_enzyme_C PF02775.21 AJA93005.1 - 3.7e-29 101.5 0.2 6e-29 100.8 0.2 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 AJA93005.1 - 4.1e-14 52.5 2.7 3e-12 46.5 2.7 2.5 1 1 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Cu-oxidase_3 PF07732.15 AJA93006.1 - 6.5e-26 90.7 5.0 2.9e-22 78.9 0.2 2.2 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 AJA93006.1 - 8.5e-21 74.1 9.9 2.6e-10 40.2 1.4 3.1 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 AJA93006.1 - 0.008 16.3 0.0 0.19 11.8 0.0 2.6 3 0 0 3 3 3 1 Cupredoxin-like domain CHB_HEX_C_1 PF13290.6 AJA93006.1 - 0.062 13.3 0.1 3.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain Acetyltransf_4 PF13420.7 AJA93007.1 - 2.5e-15 56.9 2.4 2.9e-15 56.7 2.4 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AJA93007.1 - 5.3e-15 56.3 0.1 6.5e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AJA93007.1 - 3.4e-05 24.1 0.0 4.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ribosomal_L4 PF00573.22 AJA93008.1 - 3.3e-43 147.6 0.7 3.8e-43 147.4 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ferritin PF00210.24 AJA93009.1 - 0.0064 16.4 0.3 0.0064 16.4 0.3 1.0 1 0 0 1 1 1 1 Ferritin-like domain Glyoxalase_4 PF13669.6 AJA93010.1 - 5.1e-21 75.0 0.0 5.9e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 AJA93010.1 - 2.9e-08 33.9 0.0 3.2e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AJA93010.1 - 1.1e-06 28.9 0.0 1.3e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AJA93010.1 - 0.033 15.0 0.0 0.039 14.7 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain DUF126 PF01989.16 AJA93011.1 - 2.6e-27 94.4 0.1 3.9e-27 93.8 0.1 1.3 1 0 0 1 1 1 1 Aconitase X swivel domain Ribosomal_S19e PF01090.19 AJA93012.1 - 2.7e-47 159.9 0.0 3.1e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Hjc PF01870.18 AJA93013.1 - 0.015 15.3 0.0 0.029 14.3 0.0 1.5 1 1 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) Carb_kinase PF01256.17 AJA93014.1 - 3.4e-44 151.2 0.1 4e-44 150.9 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 AJA93014.1 - 2.2e-07 30.5 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 AJA93014.1 - 4e-05 23.1 0.1 0.00011 21.6 0.1 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase Crystallin PF00525.18 AJA93014.1 - 0.11 12.7 0.0 0.49 10.6 0.0 2.1 3 0 0 3 3 3 0 Alpha crystallin A chain, N terminal Ribosomal_L26 PF16906.5 AJA93015.1 - 8.5e-16 58.2 0.1 1.5e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 AJA93015.1 - 0.0099 15.8 0.3 0.025 14.5 0.3 1.7 1 0 0 1 1 1 1 KOW motif Jak1_Phl PF17887.1 AJA93015.1 - 0.061 13.3 3.7 0.11 12.4 3.7 1.5 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain HTH_45 PF14947.6 AJA93016.1 - 1.9e-11 43.8 1.0 2.5e-11 43.4 1.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.7 AJA93016.1 - 3.9e-05 23.4 0.0 5.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AJA93016.1 - 9.8e-05 22.2 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 AJA93016.1 - 0.00051 20.5 0.0 0.00065 20.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rio2_N PF09202.11 AJA93016.1 - 0.00062 19.9 0.1 0.00075 19.7 0.1 1.1 1 0 0 1 1 1 1 Rio2, N-terminal DUF4364 PF14277.6 AJA93016.1 - 0.00068 19.4 0.4 0.00084 19.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) MarR PF01047.22 AJA93016.1 - 0.0041 17.0 0.2 0.0061 16.5 0.2 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AJA93016.1 - 0.0042 17.4 0.2 0.0054 17.1 0.2 1.2 1 0 0 1 1 1 1 Transcriptional regulator Penicillinase_R PF03965.16 AJA93016.1 - 0.0066 16.8 0.0 0.0077 16.6 0.0 1.1 1 0 0 1 1 1 1 Penicillinase repressor HTH_IclR PF09339.10 AJA93016.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain Cdc6_C PF09079.11 AJA93016.1 - 0.013 15.5 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain HTH_24 PF13412.6 AJA93016.1 - 0.014 15.0 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding RNA_pol_Rpc34 PF05158.12 AJA93016.1 - 0.014 14.8 0.1 0.015 14.7 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit DUF2250 PF10007.9 AJA93016.1 - 0.018 15.1 0.1 0.049 13.7 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Mrr_N PF14338.6 AJA93016.1 - 0.02 15.0 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Mrr N-terminal domain FtsK_gamma PF09397.10 AJA93016.1 - 0.025 14.4 0.1 0.033 14.0 0.1 1.2 1 0 0 1 1 1 0 Ftsk gamma domain DUF2513 PF10711.9 AJA93016.1 - 0.029 14.7 0.2 0.037 14.3 0.2 1.1 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_46 PF15977.5 AJA93016.1 - 0.066 13.2 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding RQC PF09382.10 AJA93016.1 - 0.085 12.6 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 RQC domain Mga PF05043.13 AJA93016.1 - 0.1 13.2 0.9 0.19 12.3 0.4 1.7 1 1 1 2 2 2 0 Mga helix-turn-helix domain Dimerisation2 PF16864.5 AJA93016.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Dimerisation domain PadR PF03551.14 AJA93016.1 - 0.13 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family CbtA PF09490.10 AJA93018.1 - 2.7e-46 158.3 5.2 3.3e-46 158.0 5.2 1.0 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) Peptidase_M50 PF02163.22 AJA93018.1 - 0.36 10.1 2.5 2.5 7.3 2.5 2.1 1 1 0 1 1 1 0 Peptidase family M50 NUDIX PF00293.28 AJA93019.1 - 5.1e-20 71.8 0.2 5.8e-20 71.7 0.2 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 AJA93019.1 - 0.024 14.2 0.0 0.037 13.6 0.0 1.3 1 1 0 1 1 1 0 Nucleotide hydrolase DHO_dh PF01180.21 AJA93020.1 - 2.9e-53 181.0 0.9 3.3e-53 180.8 0.9 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.17 AJA93020.1 - 1.2e-05 24.6 0.2 0.0036 16.4 0.1 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AJA93020.1 - 1.7e-05 24.4 0.1 0.02 14.3 0.0 2.3 2 0 0 2 2 2 2 Histidine biosynthesis protein IMPDH PF00478.25 AJA93020.1 - 0.00057 19.0 3.5 0.0011 18.0 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 AJA93020.1 - 0.0045 16.4 1.3 0.017 14.5 1.3 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase DUF561 PF04481.12 AJA93020.1 - 0.068 12.3 7.9 0.57 9.3 4.9 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF561) UPF0051 PF01458.17 AJA93021.1 - 7.1e-72 241.6 0.3 9.7e-72 241.2 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) STT3 PF02516.14 AJA93022.1 - 5.2e-37 127.9 37.2 1.3e-36 126.5 37.2 1.7 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DUF2774 PF11242.8 AJA93023.1 - 0.056 13.6 0.8 6.1 7.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) MttA_Hcf106 PF02416.16 AJA93024.1 - 7.3e-10 38.0 3.0 1.2e-09 37.4 3.0 1.4 1 1 0 1 1 1 1 mttA/Hcf106 family Sulfotransfer_1 PF00685.27 AJA93025.1 - 4.2e-16 59.2 2.3 4.7e-16 59.1 2.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 AJA93025.1 - 9e-12 45.8 0.6 1.7e-08 35.1 0.6 2.9 1 1 0 1 1 1 1 Sulfotransferase family Y_phosphatase PF00102.27 AJA93025.1 - 0.003 17.1 0.4 0.005 16.4 0.4 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Sulfotransfer_4 PF17784.1 AJA93025.1 - 0.0072 16.2 0.1 0.015 15.1 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase domain CSD PF00313.22 AJA93026.1 - 1.2e-22 79.5 3.4 1.4e-22 79.3 3.4 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AJA93026.1 - 1.4e-07 31.1 0.5 1.4e-07 31.1 0.5 1.1 1 0 0 1 1 1 1 Ribonuclease B OB domain TPR_1 PF00515.28 AJA93027.1 - 9.7e-22 75.8 0.3 1.3e-05 24.7 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 AJA93027.1 - 1.5e-17 62.2 0.0 3.1e-05 23.7 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 AJA93027.1 - 3.1e-16 58.1 0.7 0.00043 20.3 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.6 AJA93027.1 - 9.7e-12 44.7 0.0 0.0093 16.6 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 AJA93027.1 - 2.7e-11 43.0 0.1 0.0027 17.3 0.0 4.2 1 1 3 4 4 4 3 TPR repeat TPR_17 PF13431.6 AJA93027.1 - 4e-11 42.5 0.0 1.7e-05 24.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AJA93027.1 - 3e-09 37.0 0.0 4.3e-06 26.9 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 AJA93027.1 - 3.5e-09 36.7 0.0 7.7e-05 23.2 0.0 3.8 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 AJA93027.1 - 4.8e-09 36.6 0.0 0.0008 19.9 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 AJA93027.1 - 5.9e-09 36.4 0.0 0.03 14.9 0.0 3.1 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AJA93027.1 - 2.5e-08 33.4 0.0 0.014 15.4 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AJA93027.1 - 6.3e-08 32.8 0.0 0.0033 17.7 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJA93027.1 - 1.8e-05 24.7 0.1 0.51 10.5 0.0 3.9 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 AJA93027.1 - 0.00031 20.8 0.0 0.21 11.8 0.0 2.6 1 1 1 3 3 3 2 Tetratricopeptide repeat PPR PF01535.20 AJA93027.1 - 0.0014 18.7 0.4 2.7 8.5 0.0 3.8 3 0 0 3 3 3 1 PPR repeat TPR_20 PF14561.6 AJA93027.1 - 0.0053 17.1 0.0 3.2 8.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AJA93027.1 - 0.075 13.5 0.0 8.1 6.9 0.0 2.3 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_15 PF13429.6 AJA93027.1 - 0.11 11.7 0.0 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DS PF01916.17 AJA93028.1 - 7.8e-99 330.5 0.1 8.8e-99 330.4 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF5001 PF16392.5 AJA93028.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Ig-like domain Hpre_diP_synt_I PF07456.11 AJA93028.1 - 0.2 11.7 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase component I TFIIE_alpha PF02002.17 AJA93029.1 - 4.8e-17 61.7 0.9 4.8e-17 61.7 0.9 1.6 2 0 0 2 2 2 1 TFIIE alpha subunit zf-ACC PF17848.1 AJA93029.1 - 0.0019 18.2 0.2 0.0053 16.8 0.0 1.9 2 0 0 2 2 2 1 Acetyl-coA carboxylase zinc finger domain TrmB PF01978.19 AJA93029.1 - 0.0023 17.7 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB zf-ribbon_3 PF13248.6 AJA93029.1 - 0.0086 15.5 1.4 0.013 14.9 0.1 1.9 2 0 0 2 2 2 1 zinc-ribbon domain HTH_Crp_2 PF13545.6 AJA93029.1 - 0.012 15.6 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AJA93029.1 - 0.083 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator zf-C2H2_4 PF13894.6 AJA93029.1 - 0.085 13.7 1.3 0.14 13.1 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Sigma70_r3 PF04539.16 AJA93029.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 AIRC PF00731.20 AJA93030.1 - 8.1e-17 61.2 4.6 1.2e-16 60.6 4.6 1.3 1 0 0 1 1 1 1 AIR carboxylase NFACT-R_1 PF05670.13 AJA93030.1 - 0.0082 16.8 0.1 0.016 15.9 0.1 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF835 PF05763.12 AJA93030.1 - 0.051 13.3 0.9 1.5 8.6 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF835) AF0941-like PF14591.6 AJA93030.1 - 0.26 11.8 3.4 2.3 8.8 1.6 2.2 1 1 1 2 2 2 0 AF0941-like Shikimate_dh_N PF08501.11 AJA93031.1 - 6.7e-28 96.8 0.1 1.9e-27 95.3 0.0 1.8 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 AJA93031.1 - 1.9e-11 43.5 0.0 3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 AJA93031.1 - 8.3e-10 38.9 0.1 1.4e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AJA93031.1 - 0.00015 22.0 0.0 0.00026 21.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 AJA93031.1 - 0.03 14.9 0.1 0.051 14.2 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent COX15-CtaA PF02628.15 AJA93032.1 - 8.8e-19 67.7 15.8 1.6e-14 53.8 8.9 2.0 1 1 1 2 2 2 2 Cytochrome oxidase assembly protein PseudoU_synth_2 PF00849.22 AJA93032.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA pseudouridylate synthase SLATT_fungal PF18142.1 AJA93032.1 - 5.4 7.0 6.2 0.72 9.9 0.4 2.2 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Ribosomal_S13 PF00416.22 AJA93033.1 - 2.1e-37 128.4 0.1 2.5e-37 128.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 H2TH PF06831.14 AJA93033.1 - 0.0091 16.0 0.0 0.028 14.4 0.0 1.7 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain RMMBL PF07521.12 AJA93034.1 - 2.8e-05 24.0 0.0 0.00014 21.7 0.0 2.0 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain DRMBL PF07522.14 AJA93034.1 - 0.013 15.6 0.1 0.033 14.4 0.1 1.6 1 1 0 1 1 1 0 DNA repair metallo-beta-lactamase SRP19 PF01922.17 AJA93035.1 - 3e-14 53.7 0.2 3.7e-14 53.4 0.2 1.1 1 0 0 1 1 1 1 SRP19 protein MFS_1 PF07690.16 AJA93036.1 - 1.6e-35 122.7 42.8 1e-24 87.1 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AJA93036.1 - 4.1e-15 56.0 15.6 5.4e-15 55.5 15.6 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 AJA93036.1 - 0.00039 19.0 8.5 0.00057 18.4 8.5 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector PUCC PF03209.15 AJA93036.1 - 0.0088 15.1 17.0 0.61 9.0 16.1 2.7 1 1 1 2 2 2 1 PUCC protein OATP PF03137.20 AJA93036.1 - 0.067 11.5 12.6 0.033 12.5 3.9 3.0 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MASE2 PF05230.11 AJA93036.1 - 0.19 11.8 4.0 0.89 9.7 0.0 3.5 3 1 0 3 3 3 0 MASE2 domain GDP_Man_Dehyd PF16363.5 AJA93037.1 - 1.3e-66 225.3 0.0 1.6e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AJA93037.1 - 4.1e-55 186.9 0.0 4.8e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AJA93037.1 - 1.3e-16 60.6 0.0 1.1e-15 57.5 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AJA93037.1 - 6.4e-14 51.6 0.0 1.1e-13 50.9 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AJA93037.1 - 7.5e-09 35.1 0.0 9.5e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AJA93037.1 - 6e-08 32.8 0.0 1.2e-07 31.8 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AJA93037.1 - 9.6e-08 31.5 0.1 0.00012 21.3 0.1 2.4 2 1 0 2 2 2 2 Male sterility protein NmrA PF05368.13 AJA93037.1 - 0.0056 16.3 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 AJA93037.1 - 0.0075 15.7 0.0 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Bac_luciferase PF00296.20 AJA93038.1 - 6.3e-56 190.1 0.0 7.6e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase AAA PF00004.29 AJA93039.1 - 1.2e-12 48.4 0.0 5.6e-12 46.2 0.0 2.0 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AJA93039.1 - 1.7e-07 31.1 0.0 2.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 AJA93039.1 - 1.3e-05 25.3 0.0 5e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AJA93039.1 - 0.00021 21.6 0.2 0.063 13.5 0.1 2.9 2 1 1 3 3 3 1 AAA domain Rad17 PF03215.15 AJA93039.1 - 0.0013 18.6 0.0 0.0039 17.1 0.0 1.9 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 AJA93039.1 - 0.0029 18.0 0.0 0.0065 16.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 AJA93039.1 - 0.0032 17.0 0.0 0.0058 16.2 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_2 PF07724.14 AJA93039.1 - 0.0077 16.4 0.0 0.032 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_8 PF12780.7 AJA93039.1 - 0.012 15.0 0.0 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 RFC1 PF08519.12 AJA93039.1 - 0.014 15.6 1.3 0.055 13.6 0.0 2.6 3 0 0 3 3 3 0 Replication factor RFC1 C terminal domain AAA_18 PF13238.6 AJA93039.1 - 0.017 15.7 0.0 0.055 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 AJA93039.1 - 0.035 13.5 0.2 9 5.7 0.0 3.0 2 1 1 3 3 3 0 Bacterial TniB protein AAA_17 PF13207.6 AJA93039.1 - 0.051 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AJA93039.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AJA93039.1 - 0.061 13.3 0.1 0.26 11.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2067 PF09840.9 AJA93039.1 - 0.078 12.5 1.0 0.2 11.2 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) TIP49 PF06068.13 AJA93039.1 - 0.11 11.7 0.0 0.32 10.1 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain IstB_IS21 PF01695.17 AJA93039.1 - 0.11 12.2 0.1 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 AJA93039.1 - 0.18 11.7 0.5 0.93 9.4 0.1 2.2 1 1 1 2 2 2 0 NTPase ThiF PF00899.21 AJA93041.1 - 9.7e-67 224.9 0.2 1.4e-66 224.3 0.2 1.2 1 0 0 1 1 1 1 ThiF family ThiS PF02597.20 AJA93041.1 - 2.7e-10 40.8 0.0 1e-09 38.9 0.0 2.0 2 0 0 2 2 2 1 ThiS family Sacchrp_dh_NADP PF03435.18 AJA93041.1 - 2.8e-05 24.4 2.9 0.00038 20.7 2.9 2.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AJA93041.1 - 0.0035 17.4 0.2 0.015 15.4 0.1 2.0 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 AJA93041.1 - 0.0055 17.1 0.2 0.016 15.7 0.2 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 AJA93041.1 - 0.017 14.7 0.2 0.32 10.6 0.1 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 AJA93041.1 - 0.052 12.9 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.25 AJA93042.1 - 7.9e-15 55.1 0.0 9.2e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AJA93042.1 - 1e-13 51.3 0.0 1.2e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AJA93042.1 - 4.8e-10 39.7 0.1 7.4e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AJA93042.1 - 4.2e-05 23.6 0.0 6.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AJA93042.1 - 0.00045 20.3 0.0 0.00056 20.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AJA93042.1 - 0.00059 19.7 0.1 0.002 18.0 0.1 1.8 1 1 0 1 1 1 1 FR47-like protein Nop10p PF04135.12 AJA93043.1 - 2.4e-23 81.9 3.8 2.5e-23 81.8 3.8 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PolC_DP2 PF03833.13 AJA93043.1 - 0.00031 18.8 0.7 0.00031 18.8 0.7 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 RecR PF02132.15 AJA93043.1 - 0.013 15.1 1.5 0.016 14.8 1.5 1.2 1 0 0 1 1 1 0 RecR protein zf-C2H2 PF00096.26 AJA93043.1 - 4.8 7.8 7.1 5.2 7.7 1.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type THOC7 PF05615.13 AJA93044.1 - 0.0049 17.2 5.0 0.0049 17.2 5.0 4.0 1 1 2 3 3 2 1 Tho complex subunit 7 DUF4407 PF14362.6 AJA93044.1 - 0.079 12.3 22.1 1 8.7 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FliJ PF02050.16 AJA93044.1 - 0.29 11.4 24.6 0.55 10.5 7.5 3.4 1 1 3 4 4 4 0 Flagellar FliJ protein DUF745 PF05335.13 AJA93044.1 - 0.5 10.1 21.9 0.58 9.9 14.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF745) T2SSM PF04612.12 AJA93044.1 - 0.52 10.4 4.1 17 5.5 0.1 2.6 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M OmpH PF03938.14 AJA93044.1 - 0.56 10.5 38.8 19 5.6 16.6 3.0 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) ERM PF00769.19 AJA93044.1 - 0.94 9.2 39.8 1.9 8.2 26.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Corona_S2 PF01601.16 AJA93044.1 - 1.3 7.4 7.2 0.92 7.9 1.3 2.6 2 1 1 3 3 3 0 Coronavirus S2 glycoprotein CorA PF01544.18 AJA93044.1 - 2.2 7.5 22.6 0.78 9.0 8.5 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein TolA_bind_tri PF16331.5 AJA93044.1 - 2.8 8.1 15.8 0.86 9.7 0.5 3.2 2 1 1 3 3 3 0 TolA binding protein trimerisation HIP1_clath_bdg PF16515.5 AJA93044.1 - 4.1 8.1 38.6 6.2 7.5 5.9 4.0 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Muted PF14942.6 AJA93044.1 - 4.6 7.6 42.6 0.93 9.8 15.5 3.1 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein ATG16 PF08614.11 AJA93044.1 - 4.7 7.4 32.4 0.31 11.2 15.2 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.20 AJA93044.1 - 4.8 7.2 48.6 0.13 12.2 5.6 4.8 2 1 3 5 5 5 0 Prefoldin subunit RNase_H PF00075.24 AJA93044.1 - 6.5 6.9 11.5 3.6 7.8 3.8 2.8 1 1 1 2 2 2 0 RNase H Fez1 PF06818.15 AJA93044.1 - 6.5 7.2 37.2 1.5 9.2 25.9 2.2 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 AJA93044.1 - 7.2 6.7 30.4 1.1 9.4 8.8 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 AJA93044.1 - 9 3.7 36.3 18 2.7 36.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) LTD PF00932.19 AJA93045.1 - 7.5e-14 52.0 0.2 7.5e-14 52.0 0.2 3.6 3 1 0 3 3 3 1 Lamin Tail Domain Arrestin_C PF02752.22 AJA93045.1 - 4e-07 30.6 1.5 1.1 9.7 0.0 5.0 5 0 0 5 5 5 3 Arrestin (or S-antigen), C-terminal domain MG2 PF01835.19 AJA93045.1 - 0.00028 21.3 1.5 2.1 8.9 0.0 5.9 5 2 0 5 5 5 1 MG2 domain A2M_BRD PF07703.14 AJA93045.1 - 0.0003 21.2 0.1 0.49 10.7 0.0 3.8 4 1 0 4 4 4 2 Alpha-2-macroglobulin bait region domain FNIP_C PF14638.6 AJA93045.1 - 0.094 12.3 0.1 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Folliculin-interacting protein C-terminus Semialdhyde_dhC PF02774.18 AJA93046.1 - 2.8e-32 112.3 0.0 5e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AJA93046.1 - 4.1e-28 98.2 0.1 1e-27 96.9 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 AJA93046.1 - 0.037 14.7 0.0 0.089 13.5 0.0 1.6 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 AJA93046.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.20 AJA93046.1 - 0.1 12.2 0.3 1.9 8.1 0.0 2.4 3 0 0 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DNA_binding_1 PF01035.20 AJA93048.1 - 8.1e-30 102.8 0.0 9.2e-30 102.6 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain SprT-like PF10263.9 AJA93049.1 - 0.00018 21.3 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_M76 PF09768.9 AJA93049.1 - 0.0045 16.8 0.0 0.0054 16.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family DUF45 PF01863.17 AJA93049.1 - 0.005 16.9 0.0 0.0077 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 Tox-MPTase5 PF15641.6 AJA93049.1 - 0.057 13.5 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 5 Aminopep PF10023.9 AJA93049.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative aminopeptidase MCM PF00493.23 AJA93051.1 - 8.7e-95 316.1 0.0 1.3e-94 315.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 AJA93051.1 - 4e-34 117.2 0.0 7.1e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 AJA93051.1 - 1.2e-22 80.1 0.8 2.5e-22 79.1 0.8 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 AJA93051.1 - 2.2e-09 37.9 0.4 2.2e-09 37.9 0.4 2.7 4 0 0 4 4 4 1 MCM N-terminal domain AAA_5 PF07728.14 AJA93051.1 - 1.3e-05 25.2 0.0 0.00058 19.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AJA93051.1 - 1.8e-05 24.2 0.0 0.0008 18.8 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AJA93051.1 - 0.0077 16.1 0.1 0.029 14.2 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AJA93051.1 - 0.028 14.1 1.2 0.2 11.3 0.3 2.6 2 0 0 2 2 2 0 AAA domain DALR_1 PF05746.15 AJA93051.1 - 0.61 10.3 2.7 8.1 6.7 0.0 3.2 3 0 0 3 3 3 0 DALR anticodon binding domain ABC-3 PF00950.17 AJA93052.1 - 4.7e-67 226.2 37.2 5.3e-67 226.0 37.2 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AJA93052.1 - 3.1e-06 26.4 35.0 3.1e-06 26.4 35.0 1.9 1 1 1 2 2 2 1 FecCD transport family zf-C2H2 PF00096.26 AJA93054.1 - 0.00037 20.8 0.4 0.0006 20.1 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type Actin_micro PF17003.5 AJA93054.1 - 0.00077 18.7 0.1 0.00082 18.7 0.1 1.0 1 0 0 1 1 1 1 Putative actin-like family zf-C2H2_4 PF13894.6 AJA93054.1 - 0.0036 18.0 0.3 0.0056 17.4 0.3 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-BED PF02892.15 AJA93054.1 - 0.0053 16.8 1.4 0.0091 16.0 1.4 1.4 1 1 0 1 1 1 1 BED zinc finger DUF629 PF04780.12 AJA93054.1 - 0.0062 15.1 0.1 0.0066 15.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 AJA93054.1 - 0.023 15.0 0.1 0.024 15.0 0.1 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3 PF13878.6 AJA93054.1 - 0.05 13.4 0.1 0.078 12.8 0.1 1.3 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_11 PF16622.5 AJA93054.1 - 0.061 13.1 1.1 0.11 12.3 1.1 1.4 1 1 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 AJA93054.1 - 0.078 13.7 0.0 0.084 13.6 0.0 1.1 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats LapA_dom PF06305.11 AJA93055.1 - 0.0029 17.4 1.9 1.2 9.0 0.1 2.1 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain DUF2749 PF10907.8 AJA93055.1 - 0.043 14.0 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Topoisom_I PF01028.20 AJA93056.1 - 6.8e-66 221.8 8.3 6.8e-66 221.8 8.3 2.5 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 AJA93056.1 - 2.2e-63 213.6 9.6 2.2e-63 213.6 9.6 2.5 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 AJA93056.1 - 1.8e-19 69.5 1.7 1.8e-19 69.5 1.7 3.9 3 0 0 3 3 3 1 C-terminal topoisomerase domain DUF2524 PF10732.9 AJA93056.1 - 0.023 15.0 1.9 0.12 12.7 1.9 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) DUF3137 PF11335.8 AJA93056.1 - 0.046 13.7 5.6 0.036 14.0 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) LMBR1 PF04791.16 AJA93056.1 - 0.72 8.7 5.0 1.2 7.9 5.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 AJA93056.1 - 4.3 6.6 12.8 19 4.5 8.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Glyco_tranf_2_3 PF13641.6 AJA93057.1 - 7.9e-24 84.8 0.0 1.2e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AJA93057.1 - 6.9e-19 68.5 0.2 1.5e-18 67.5 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 AJA93057.1 - 7e-18 65.0 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AJA93057.1 - 2.3e-13 50.0 0.1 4.4e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 AJA93057.1 - 0.0026 16.3 1.8 0.0031 16.1 0.3 1.8 2 0 0 2 2 2 1 Cellulose synthase HlyIII PF03006.20 AJA93057.1 - 0.012 15.4 0.2 0.11 12.1 0.0 2.6 2 1 0 2 2 2 0 Haemolysin-III related CytochromB561_N PF09786.9 AJA93057.1 - 0.1 11.6 0.3 0.23 10.4 0.3 1.5 1 0 0 1 1 1 0 Cytochrome B561, N terminal PyrI PF01948.18 AJA93058.1 - 5e-31 106.8 0.8 7.6e-31 106.2 0.8 1.3 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.15 AJA93058.1 - 4e-16 58.7 1.6 6.2e-16 58.0 1.6 1.3 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-RING_7 PF02591.15 AJA93058.1 - 0.011 15.9 1.0 0.034 14.3 0.1 2.3 3 0 0 3 3 3 0 C4-type zinc ribbon domain DUF1936 PF09151.10 AJA93058.1 - 0.099 12.6 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) TP_methylase PF00590.20 AJA93059.1 - 6.6e-46 156.9 0.1 7.8e-46 156.7 0.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.21 AJA93059.1 - 0.00036 20.9 0.1 0.00064 20.1 0.1 1.4 1 1 0 1 1 1 1 Radical SAM superfamily Aldolase PF01081.19 AJA93059.1 - 0.011 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 KDPG and KHG aldolase Asp_Glu_race PF01177.22 AJA93059.1 - 0.047 13.5 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase HSP70 PF00012.20 AJA93060.1 - 6.8e-217 721.4 22.0 1.8e-195 650.6 19.3 2.2 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 AJA93060.1 - 3.5e-19 68.8 6.9 3.5e-19 68.8 6.9 2.7 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 AJA93060.1 - 0.03 14.0 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4376 PF14301.6 AJA93060.1 - 0.18 12.2 3.3 2.1 8.8 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4376) FtsA PF14450.6 AJA93060.1 - 2.8 8.4 8.9 18 5.8 1.9 3.5 3 1 0 3 3 3 0 Cell division protein FtsA Spt4 PF06093.13 AJA93061.1 - 4.4e-13 49.1 0.7 5.5e-13 48.8 0.7 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RecR PF02132.15 AJA93061.1 - 0.019 14.5 5.3 0.025 14.1 5.3 1.2 1 0 0 1 1 1 0 RecR protein zf-RRN7 PF11781.8 AJA93061.1 - 0.62 9.8 7.0 1.1 9.0 0.2 2.1 1 1 1 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 NAD_kinase PF01513.21 AJA93063.1 - 8.5e-30 103.9 0.1 1.2e-29 103.4 0.1 1.2 1 0 0 1 1 1 1 ATP-NAD kinase HTH_24 PF13412.6 AJA93063.1 - 0.00016 21.2 0.7 0.00078 18.9 0.0 2.5 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AJA93063.1 - 0.00086 19.2 0.7 0.0081 16.1 0.1 2.5 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AJA93063.1 - 0.0017 18.8 0.1 0.0039 17.6 0.1 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 AJA93063.1 - 0.0028 17.5 0.9 0.019 14.8 0.6 2.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB TPALS PF18178.1 AJA93063.1 - 0.023 14.2 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family RNA_pol_Rpc34 PF05158.12 AJA93063.1 - 0.035 13.5 2.3 0.055 12.8 2.3 1.3 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit Penicillinase_R PF03965.16 AJA93063.1 - 0.088 13.2 0.4 0.26 11.6 0.2 1.9 2 0 0 2 2 2 0 Penicillinase repressor Response_reg PF00072.24 AJA93064.1 - 0.033 14.4 0.2 0.077 13.2 0.0 1.8 2 1 0 2 2 2 0 Response regulator receiver domain Cas_DxTHG PF09455.10 AJA93064.1 - 0.046 13.3 5.1 0.052 13.1 5.1 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family OrfB_IS605 PF01385.19 AJA93064.1 - 0.16 12.2 0.9 0.55 10.5 0.2 1.8 2 0 0 2 2 2 0 Probable transposase PDH PF02153.17 AJA93065.1 - 2.2e-26 92.5 0.3 2.8e-26 92.1 0.3 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 AJA93065.1 - 6.1e-07 29.7 0.2 3.2e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AJA93065.1 - 1.1e-05 26.0 0.5 3.8e-05 24.2 0.0 2.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AJA93065.1 - 0.00011 21.7 0.1 0.00025 20.5 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 AJA93065.1 - 0.0015 18.2 0.1 0.0078 15.9 0.1 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA CoA_binding_2 PF13380.6 AJA93065.1 - 0.0016 18.9 0.0 0.025 15.1 0.0 2.5 2 0 0 2 2 2 1 CoA binding domain 3HCDH_N PF02737.18 AJA93065.1 - 0.0026 17.7 0.2 0.0075 16.2 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 AJA93065.1 - 0.0077 16.7 1.2 1.1 9.7 0.2 3.3 2 2 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF1392 PF07154.11 AJA93065.1 - 0.013 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1392) DpaA_N PF16924.5 AJA93065.1 - 0.015 15.4 0.2 0.061 13.4 0.0 2.2 2 1 1 3 3 3 0 Dipicolinate synthase subunit A N-terminal domain Epimerase PF01370.21 AJA93065.1 - 0.017 14.6 0.0 0.092 12.2 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.23 AJA93065.1 - 0.028 14.4 1.2 0.83 9.6 0.1 2.6 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short PF00106.25 AJA93065.1 - 0.06 12.8 0.2 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase CUTL PF16557.5 AJA93065.1 - 0.097 12.9 0.6 0.25 11.6 0.1 1.9 1 1 0 1 1 1 0 CUT1-like DNA-binding domain of SATB Cas_Csa5 PF09702.10 AJA93065.1 - 0.12 12.6 1.5 3.2 8.1 0.2 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) Ldh_1_N PF00056.23 AJA93066.1 - 2.9e-38 131.1 0.6 5.4e-38 130.3 0.6 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AJA93066.1 - 8.1e-27 94.2 0.1 1.2e-26 93.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 AJA93066.1 - 0.023 14.3 0.7 0.61 9.6 0.0 2.5 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase zinc_ribbon_4 PF13717.6 AJA93067.1 - 0.00021 21.2 0.3 0.54 10.2 0.0 2.1 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AJA93067.1 - 0.00029 20.3 1.3 0.0004 19.9 1.3 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding RNA_POL_M_15KD PF02150.16 AJA93067.1 - 0.002 18.0 1.0 0.003 17.4 1.0 1.3 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.6 AJA93067.1 - 0.0028 18.0 1.0 0.0032 17.8 1.0 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar DNA_RNApol_7kD PF03604.13 AJA93067.1 - 0.0044 16.7 3.1 0.16 11.7 0.2 2.4 2 1 1 3 3 3 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.6 AJA93067.1 - 0.015 15.0 0.3 0.032 14.0 0.3 1.6 1 1 1 2 2 2 0 zinc-ribbon domain HypA PF01155.19 AJA93067.1 - 0.017 15.1 0.6 0.019 15.0 0.6 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_recom PF13408.6 AJA93067.1 - 0.029 14.9 0.1 0.83 10.2 0.0 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Ogr_Delta PF04606.12 AJA93067.1 - 0.031 14.3 0.2 1.4 9.0 0.2 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zinc-ribbons_6 PF07191.12 AJA93067.1 - 0.039 13.9 0.3 0.052 13.5 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-HYPF PF07503.12 AJA93067.1 - 0.041 13.7 2.4 0.63 9.9 2.4 2.1 1 1 0 1 1 1 0 HypF finger Elf1 PF05129.13 AJA93067.1 - 0.076 13.1 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 AJA93067.1 - 0.077 13.1 0.5 5.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Prok-RING_1 PF14446.6 AJA93067.1 - 0.12 12.3 4.1 0.22 11.5 4.1 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 AJA93067.1 - 0.13 11.9 1.3 3.6 7.3 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 AJA93067.1 - 0.17 12.7 1.2 1.1 10.1 0.0 2.0 1 1 1 2 2 2 0 zinc-ribbon family PTH2 PF01981.16 AJA93068.1 - 8.5e-39 132.5 0.0 9.4e-39 132.3 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 zinc_ribbon_4 PF13717.6 AJA93069.1 - 2.2e-08 33.9 3.8 2.7e-05 24.0 1.3 2.1 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.6 AJA93069.1 - 9e-07 28.6 3.0 0.00021 21.0 0.8 2.0 1 1 1 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 AJA93069.1 - 6.5e-05 22.2 1.0 0.18 11.3 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 AJA93069.1 - 0.0002 21.2 0.7 0.00025 20.9 0.7 1.2 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit Prok-RING_1 PF14446.6 AJA93069.1 - 0.00022 21.1 3.8 0.00073 19.4 3.8 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 AJA93069.1 - 0.0003 20.3 1.3 0.14 11.8 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-IS66 PF13005.7 AJA93069.1 - 0.00037 20.8 1.1 0.27 11.7 0.1 2.2 1 1 1 2 2 2 2 zinc-finger binding domain of transposase IS66 TF_Zn_Ribbon PF08271.12 AJA93069.1 - 0.0006 19.3 1.7 0.00074 19.0 1.7 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding UPF0547 PF10571.9 AJA93069.1 - 0.00096 19.2 3.1 0.4 10.8 0.2 2.2 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 zf-RING_7 PF02591.15 AJA93069.1 - 0.0011 19.2 4.9 0.0063 16.7 0.4 2.5 2 1 0 2 2 2 1 C4-type zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 AJA93069.1 - 0.002 18.0 5.5 0.052 13.5 2.8 2.0 1 1 1 2 2 2 2 PhnA Zinc-Ribbon zf-C4_Topoisom PF01396.19 AJA93069.1 - 0.0023 17.7 1.7 0.67 9.8 0.1 2.1 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger IBR PF01485.21 AJA93069.1 - 0.0026 17.9 0.7 0.0034 17.6 0.7 1.1 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain YacG PF03884.14 AJA93069.1 - 0.0031 17.2 0.9 0.38 10.5 0.0 2.2 2 0 0 2 2 2 1 DNA gyrase inhibitor YacG Ogr_Delta PF04606.12 AJA93069.1 - 0.0037 17.2 2.3 1 9.4 0.2 2.1 2 0 0 2 2 2 2 Ogr/Delta-like zinc finger zf-TFIIB PF13453.6 AJA93069.1 - 0.0038 16.5 2.4 0.066 12.5 3.8 1.9 1 1 1 2 2 2 2 Transcription factor zinc-finger DNA_ligase_ZBD PF03119.16 AJA93069.1 - 0.005 16.8 1.2 0.94 9.6 0.1 2.3 2 0 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain BssC_TutF PF08201.11 AJA93069.1 - 0.008 16.2 1.2 0.26 11.3 0.2 2.0 2 0 0 2 2 2 1 BssC/TutF protein DZR PF12773.7 AJA93069.1 - 0.0099 15.9 1.1 0.016 15.2 1.1 1.5 1 1 0 1 1 1 1 Double zinc ribbon zinc-ribbons_6 PF07191.12 AJA93069.1 - 0.014 15.4 0.9 0.038 14.0 0.9 1.7 1 1 0 1 1 1 0 zinc-ribbons A2L_zn_ribbon PF08792.10 AJA93069.1 - 0.015 15.0 2.2 0.17 11.7 0.2 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.10 AJA93069.1 - 0.016 15.3 5.0 0.78 9.9 0.4 2.2 1 1 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 AJA93069.1 - 0.017 15.1 0.2 0.023 14.6 0.2 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain HypA PF01155.19 AJA93069.1 - 0.017 15.1 0.3 0.018 15.0 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_6 PF13912.6 AJA93069.1 - 0.018 15.1 1.3 0.7 10.0 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 AJA93069.1 - 0.04 14.2 4.4 0.28 11.5 4.4 2.0 1 1 0 1 1 1 0 zinc-ribbon CpXC PF14353.6 AJA93069.1 - 0.047 13.7 2.6 0.88 9.6 0.2 2.1 1 1 1 2 2 2 0 CpXC protein Zn_Tnp_IS1595 PF12760.7 AJA93069.1 - 0.047 13.7 0.1 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cys_rich_CPXG PF14255.6 AJA93069.1 - 0.051 13.5 0.9 3.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Cysteine-rich CPXCG DNA_RNApol_7kD PF03604.13 AJA93069.1 - 0.051 13.3 2.5 0.16 11.7 2.5 1.7 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit PriA_CRR PF18319.1 AJA93069.1 - 0.061 13.3 1.2 1.2 9.2 0.2 2.1 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain PADR1 PF08063.12 AJA93069.1 - 0.067 13.0 3.0 0.73 9.7 0.1 2.1 1 1 1 2 2 2 0 PADR1 (NUC008) domain ADK_lid PF05191.14 AJA93069.1 - 0.068 13.2 0.3 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-H2C2_2 PF13465.6 AJA93069.1 - 0.074 13.5 1.4 1.8 9.2 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 AJA93069.1 - 0.1 13.5 0.4 3.3 8.8 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2HC_14 PF18574.1 AJA93069.1 - 0.1 12.4 0.2 8.3 6.3 0.0 2.1 2 0 0 2 2 2 0 C2HC Zing finger domain zf-HYPF PF07503.12 AJA93069.1 - 0.16 11.8 4.6 1.7 8.5 4.5 2.0 1 1 0 1 1 1 0 HypF finger TerY_C PF15616.6 AJA93069.1 - 0.16 12.1 0.9 0.79 9.8 0.9 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain Lar_restr_allev PF14354.6 AJA93069.1 - 0.16 12.4 2.1 0.2 12.1 2.1 1.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-ACC PF17848.1 AJA93069.1 - 0.19 11.9 4.7 6.1 7.0 0.4 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Zn_ribbon_recom PF13408.6 AJA93069.1 - 0.21 12.1 0.4 7.8 7.1 0.0 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF1451 PF07295.11 AJA93069.1 - 0.25 11.4 0.8 0.32 11.0 0.8 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zinc_ribbon_2 PF13240.6 AJA93069.1 - 0.3 10.8 4.8 7.6 6.4 4.8 2.5 1 1 0 1 1 1 0 zinc-ribbon domain zf-C2H2 PF00096.26 AJA93069.1 - 0.33 11.5 1.1 3.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Anti-TRAP PF15777.5 AJA93069.1 - 0.36 10.8 3.3 0.55 10.2 3.3 1.4 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF3797 PF12677.7 AJA93069.1 - 1.7 8.6 5.7 4.3 7.3 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) SNO PF01174.19 AJA93070.1 - 4.1e-49 167.0 0.3 4.7e-49 166.8 0.3 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 AJA93070.1 - 4.4e-12 46.0 0.0 7e-12 45.4 0.0 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 AJA93070.1 - 7.8e-11 42.1 0.0 1.2e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJA93070.1 - 1.8e-06 27.9 0.3 0.00013 21.8 0.2 2.7 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 AJA93070.1 - 1.8e-05 24.6 0.1 3.9e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 AJA93070.1 - 6e-05 22.8 0.2 8.7e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase family S51 BPL_N PF09825.9 AJA93070.1 - 9.2e-05 21.7 0.0 0.36 9.9 0.0 2.2 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal ChlI PF13541.6 AJA93070.1 - 0.025 14.4 0.3 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase CopD PF05425.13 AJA93071.1 - 9.3e-17 61.4 2.2 9.3e-17 61.4 2.2 1.4 2 0 0 2 2 2 1 Copper resistance protein D DUF4149 PF13664.6 AJA93071.1 - 0.00015 22.0 2.6 0.00015 22.0 2.6 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4149) UPF0093 PF03653.13 AJA93071.1 - 0.0091 16.2 11.0 0.03 14.5 11.0 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0093) DUF3278 PF11683.8 AJA93071.1 - 0.025 14.7 3.8 0.044 13.9 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Brr6_like_C_C PF10104.9 AJA93071.1 - 0.34 10.7 2.5 0.3 10.9 0.5 2.0 1 1 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain FeS_assembly_P PF01883.19 AJA93072.1 - 9e-16 57.8 0.1 1.2e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein SelR PF01641.18 AJA93073.1 - 3e-53 179.0 0.4 3.5e-53 178.8 0.4 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 AJA93073.1 - 0.0016 18.6 0.1 0.0035 17.5 0.1 1.6 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2757 PF10955.8 AJA93073.1 - 0.0018 18.5 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2757) DUF983 PF06170.12 AJA93073.1 - 0.0031 17.9 0.6 0.35 11.3 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF983) Zn-ribbon_8 PF09723.10 AJA93073.1 - 0.041 14.0 0.4 9.5 6.4 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-HIT PF04438.16 AJA93073.1 - 0.077 12.9 3.2 1.2 9.1 0.3 2.4 2 0 0 2 2 2 0 HIT zinc finger zf-C2HC5 PF06221.13 AJA93073.1 - 0.11 12.6 0.6 3.4 7.7 0.1 2.3 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.6 AJA93073.1 - 0.21 11.1 2.3 8.2 6.0 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain CPBP PF02517.16 AJA93074.1 - 0.0065 16.8 3.8 0.0065 16.8 3.8 3.0 2 1 1 3 3 3 1 CPBP intramembrane metalloprotease NADH_oxidored PF08040.11 AJA93074.1 - 0.27 11.0 0.1 0.27 11.0 0.1 1.9 2 0 0 2 2 2 0 MNLL subunit UPF0147 PF03685.13 AJA93075.1 - 4.7e-27 93.9 0.7 5.3e-27 93.7 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) UPF0253 PF06786.12 AJA93075.1 - 0.0037 17.5 0.0 1.1 9.6 0.0 2.2 1 1 0 2 2 2 2 Uncharacterised protein family (UPF0253) DUF3783 PF12646.7 AJA93075.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3783) DUF2497 PF10691.9 AJA93075.1 - 0.11 13.0 0.7 0.31 11.5 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Presenilin PF01080.17 AJA93076.1 - 0.22 10.2 5.8 0.31 9.7 5.8 1.2 1 0 0 1 1 1 0 Presenilin TMCCDC2 PF15844.5 AJA93076.1 - 0.33 10.9 0.1 0.33 10.9 0.1 2.3 2 2 1 3 3 3 0 Transmembrane and coiled-coil domain-containing protein 2 DUF2070 PF09843.9 AJA93076.1 - 1.7 6.9 11.3 2 6.6 11.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4131 PF13567.6 AJA93076.1 - 2.5 7.7 5.3 4.6 6.9 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) AsnC_trans_reg PF01037.21 AJA93077.1 - 9.2e-14 51.2 0.0 1.3e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AJA93077.1 - 8.3e-11 41.3 1.5 1.3e-10 40.7 1.5 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AJA93077.1 - 9.6e-08 31.7 0.2 1.6e-07 31.0 0.2 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 AJA93077.1 - 0.00043 20.2 0.4 0.00085 19.2 0.4 1.5 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 AJA93077.1 - 0.00054 19.8 0.2 0.00098 19.0 0.2 1.4 1 0 0 1 1 1 1 MarR family B-block_TFIIIC PF04182.12 AJA93077.1 - 0.004 17.3 0.2 0.0059 16.7 0.2 1.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Mga PF05043.13 AJA93077.1 - 0.012 16.2 0.6 0.02 15.4 0.6 1.3 1 0 0 1 1 1 0 Mga helix-turn-helix domain Ribosomal_S25 PF03297.15 AJA93077.1 - 0.025 14.8 0.4 0.042 14.0 0.4 1.3 1 0 0 1 1 1 0 S25 ribosomal protein IMCp PF12314.8 AJA93077.1 - 0.081 13.2 1.0 1.5 9.2 0.0 2.5 3 0 0 3 3 3 0 Inner membrane complex protein Cadherin_2 PF08266.12 AJA93077.1 - 0.1 12.5 0.2 0.49 10.3 0.1 2.0 2 0 0 2 2 2 0 Cadherin-like AsnC_trans_reg PF01037.21 AJA93078.1 - 4.9e-09 36.0 0.0 5.5e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain FtsX_ECD PF18075.1 AJA93078.1 - 0.064 13.9 0.1 0.096 13.3 0.1 1.4 1 1 0 1 1 1 0 FtsX extracellular domain DUF2935 PF11155.8 AJA93081.1 - 0.068 13.5 2.4 0.71 10.2 2.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Styelin PF17562.2 AJA93081.1 - 0.079 13.3 0.4 0.44 10.9 0.1 2.1 2 0 0 2 2 2 0 Styelin 7TMR-DISM_7TM PF07695.11 AJA93082.1 - 0.012 15.5 9.0 0.014 15.3 9.0 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling YtpI PF14007.6 AJA93082.1 - 0.018 15.2 2.8 0.018 15.2 2.8 2.6 2 1 1 3 3 3 0 YtpI-like protein Cation_ATPase_C PF00689.21 AJA93082.1 - 0.09 12.5 8.6 0.094 12.4 5.3 1.9 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Bac_export_2 PF01312.19 AJA93082.1 - 1.5 7.9 9.3 3.6 6.7 0.4 2.0 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family DnaJ_C PF01556.18 AJA93083.1 - 2.2e-36 125.2 0.0 3.8e-36 124.4 0.0 1.4 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AJA93083.1 - 2.7e-25 88.3 1.0 4.4e-25 87.6 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AJA93083.1 - 7e-12 45.5 18.9 1.2e-11 44.7 18.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AJA93083.1 - 8.4 6.5 20.9 6 6.9 4.3 2.6 1 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF354 PF04007.12 AJA93084.1 - 1.6e-42 145.8 2.3 2e-42 145.5 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF354) Epimerase_2 PF02350.19 AJA93084.1 - 0.0032 16.4 0.1 0.0043 15.9 0.1 1.2 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase RTT107_BRCT_6 PF16771.5 AJA93084.1 - 0.027 14.7 1.2 0.027 14.7 1.2 2.4 2 1 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Cupredoxin_1 PF13473.6 AJA93085.1 - 1.7e-07 31.3 0.0 2e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 Cupredoxin-like domain Copper-bind PF00127.20 AJA93085.1 - 8.7e-06 26.1 0.1 8.7e-06 26.1 0.1 2.9 2 2 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family HC2 PF07382.11 AJA93085.1 - 0.00014 22.0 28.3 0.00021 21.4 28.3 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 V-set PF07686.17 AJA93085.1 - 0.0042 17.2 0.1 1.7 8.9 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin V-set domain RR_TM4-6 PF06459.12 AJA93085.1 - 0.3 10.9 4.0 0.39 10.5 4.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LPMO_10 PF03067.15 AJA93085.1 - 1.7 9.2 6.3 4.5 7.9 6.3 1.7 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading RNA_pol_Rpc4 PF05132.14 AJA93085.1 - 8.4 6.8 7.1 1.3 9.4 2.8 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 CTP_transf_3 PF02348.19 AJA93086.1 - 1.8e-32 113.0 0.4 2.3e-32 112.7 0.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AJA93086.1 - 0.0086 16.5 0.0 0.028 14.8 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain IMS PF00817.20 AJA93087.1 - 1.9e-40 138.3 0.1 7.1e-40 136.4 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 AJA93087.1 - 2.6e-09 37.8 0.1 5.2e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AJA93087.1 - 1.3e-07 31.5 0.0 4.7e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 IMS family HHH motif Cdd1 PF11731.8 AJA93087.1 - 0.0012 19.0 0.0 0.011 15.9 0.0 2.5 1 1 2 3 3 3 1 Pathogenicity locus Methyltransf_33 PF10017.9 AJA93088.1 - 2.6e-100 335.6 1.8 3e-100 335.4 1.8 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DUF1825 PF08855.10 AJA93088.1 - 0.0037 17.2 0.7 0.3 11.0 0.2 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF1825) DZR PF12773.7 AJA93089.1 - 0.00019 21.4 0.2 0.00024 21.1 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon DpnI PF06044.12 AJA93089.1 - 0.0076 15.9 0.1 0.01 15.5 0.1 1.2 1 0 0 1 1 1 1 Dam-replacing family DUF35_N PF12172.8 AJA93089.1 - 0.0085 15.9 1.6 0.94 9.4 0.0 2.4 2 1 0 2 2 2 1 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn-ribbon_8 PF09723.10 AJA93089.1 - 0.0093 16.1 0.1 0.41 10.8 0.0 2.2 2 0 0 2 2 2 1 Zinc ribbon domain C1_4 PF07975.12 AJA93089.1 - 0.022 15.0 1.6 0.95 9.7 2.3 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain DNA_RNApol_7kD PF03604.13 AJA93089.1 - 0.052 13.2 2.4 1.3 8.7 0.6 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2 PF00096.26 AJA93089.1 - 0.055 13.9 1.0 0.77 10.3 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 AJA93089.1 - 0.087 12.7 1.6 7.8 6.5 0.2 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-HYPF PF07503.12 AJA93089.1 - 0.098 12.4 2.3 3.2 7.6 0.4 2.4 2 0 0 2 2 2 0 HypF finger zf-IS66 PF13005.7 AJA93089.1 - 0.19 12.1 4.4 0.36 11.3 0.2 2.5 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-C2H2_4 PF13894.6 AJA93089.1 - 0.24 12.3 1.2 3.4 8.7 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 AJA93089.1 - 0.39 10.7 3.5 3.7 7.5 3.6 2.2 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-RING_4 PF14570.6 AJA93090.1 - 0.00055 19.7 0.5 0.17 11.7 0.0 2.1 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 AJA93090.1 - 0.0013 18.5 1.1 0.11 12.4 0.1 2.2 2 0 0 2 2 2 1 Rad50 zinc hook motif Prok-RING_4 PF14447.6 AJA93090.1 - 0.013 15.4 0.5 3.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zinc_ribbon_4 PF13717.6 AJA93090.1 - 0.025 14.5 0.6 0.97 9.4 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AJA93090.1 - 0.028 14.4 0.2 0.034 14.1 0.2 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_9 PF14369.6 AJA93090.1 - 0.033 14.4 2.3 1.1 9.5 0.4 2.1 1 1 1 2 2 2 0 zinc-ribbon zf-H2C2_2 PF13465.6 AJA93090.1 - 0.044 14.2 0.7 2.3 8.8 0.0 2.2 2 1 0 2 2 2 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.15 AJA93090.1 - 0.058 13.4 1.3 0.38 10.8 1.4 1.9 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C3HC4_3 PF13920.6 AJA93090.1 - 0.067 13.1 3.6 0.81 9.6 0.3 2.1 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 AJA93090.1 - 0.13 12.6 2.6 5.5 7.4 0.1 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF4451 PF14616.6 AJA93090.1 - 0.2 11.9 2.0 1.1 9.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) PhnA_Zn_Ribbon PF08274.12 AJA93090.1 - 0.21 11.6 2.1 5.6 7.0 0.2 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn-C2H2_12 PF18112.1 AJA93090.1 - 2.2 8.8 5.7 8.9 6.9 1.4 2.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Nitroreductase PF00881.24 AJA93091.1 - 5.3e-26 91.7 0.2 9.9e-14 51.7 0.0 2.1 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 AJA93091.1 - 2.1e-09 37.3 0.3 0.0004 20.0 0.0 2.8 2 1 0 2 2 2 2 Putative TM nitroreductase ABC_tran PF00005.27 AJA93092.1 - 2.5e-26 92.8 0.1 3.4e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AJA93092.1 - 1.1e-18 67.5 0.1 1.9e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AJA93092.1 - 5.7e-05 23.1 0.8 0.00043 20.2 0.0 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AJA93092.1 - 9.9e-05 21.9 2.3 0.00018 21.0 2.3 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain PRK PF00485.18 AJA93092.1 - 0.0019 18.0 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 AJA93092.1 - 0.061 13.0 0.0 0.1 12.2 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NAD_binding_1 PF00175.21 AJA93093.1 - 3.1e-12 47.1 0.0 5.1e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AJA93093.1 - 4.6e-08 33.3 0.0 7.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Methyltransf_34 PF11312.8 AJA93093.1 - 0.0084 15.4 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase NAD_binding_6 PF08030.12 AJA93093.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain NUDIX PF00293.28 AJA93094.1 - 2.8e-18 66.2 0.0 3.6e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain HTH_micro PF17007.5 AJA93095.1 - 0.00095 18.1 0.5 0.0013 17.7 0.5 1.1 1 0 0 1 1 1 1 HTH-like HTH_24 PF13412.6 AJA93095.1 - 0.0041 16.6 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AJA93095.1 - 0.0044 16.9 0.1 0.01 15.7 0.1 1.6 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AJA93095.1 - 0.031 14.2 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 MarR family MttA_Hcf106 PF02416.16 AJA93096.1 - 1.1e-10 40.7 0.3 1.5e-10 40.3 0.0 1.4 2 0 0 2 2 2 1 mttA/Hcf106 family AI-2E_transport PF01594.16 AJA93096.1 - 0.0048 16.1 0.0 0.006 15.8 0.0 1.0 1 0 0 1 1 1 1 AI-2E family transporter Lip_A_acyltrans PF03279.13 AJA93096.1 - 0.022 13.9 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Trypan_glycop PF00913.19 AJA93096.1 - 0.032 13.5 2.3 0.038 13.3 2.3 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) OAD_gamma PF04277.13 AJA93096.1 - 0.053 14.1 0.7 0.076 13.6 0.6 1.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Porphobil_deam PF01379.20 AJA93097.1 - 4.9e-72 241.7 0.0 6.2e-72 241.4 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 AJA93097.1 - 7.8e-16 58.2 0.0 2.2e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Fer4 PF00037.27 AJA93099.1 - 9e-10 38.0 12.0 2e-06 27.3 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJA93099.1 - 8.3e-09 35.9 3.7 1.1e-08 35.5 3.7 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJA93099.1 - 1e-07 31.9 1.6 1.5e-07 31.4 1.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJA93099.1 - 3.5e-06 27.1 3.9 1.2e-05 25.4 4.1 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AJA93099.1 - 8.4e-06 25.6 10.0 0.0086 16.1 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AJA93099.1 - 3.4e-05 23.7 7.7 0.016 15.3 1.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AJA93099.1 - 0.00017 21.6 8.0 0.0041 17.2 9.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AJA93099.1 - 0.00021 21.5 6.5 0.075 13.6 1.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AJA93099.1 - 0.00028 21.4 4.4 0.12 12.9 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_16 PF13484.6 AJA93099.1 - 0.00062 20.7 6.2 0.057 14.4 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 AJA93099.1 - 0.00078 20.2 2.8 0.13 13.2 0.6 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AJA93099.1 - 0.0013 19.6 11.5 0.089 13.8 3.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AJA93099.1 - 0.0024 18.3 5.8 0.018 15.4 5.8 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AJA93099.1 - 0.01 16.3 5.8 0.27 11.8 5.8 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AJA93099.1 - 0.19 12.5 10.9 1e+02 3.7 10.9 2.9 1 1 0 1 1 1 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 AJA93099.1 - 1.1 9.5 10.6 2.1 8.6 2.9 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain HalOD2 PF18547.1 AJA93100.1 - 0.084 12.8 1.2 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 Halobacterial output domain 2 RbpA PF13397.6 AJA93100.1 - 0.14 12.8 0.1 14 6.4 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase-binding protein Aconitase PF00330.20 AJA93101.1 - 6.5e-145 483.7 0.0 8.9e-145 483.2 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 AJA93101.1 - 9e-37 126.3 0.0 1.9e-36 125.3 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 AJA93101.1 - 0.13 11.0 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) DUF4412 PF14371.6 AJA93102.1 - 0.043 13.6 2.4 0.042 13.6 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) CEBP_ZZ PF16366.5 AJA93102.1 - 0.052 13.8 6.9 0.053 13.8 6.9 1.1 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain PolC_DP2 PF03833.13 AJA93102.1 - 0.76 7.6 4.7 0.69 7.7 4.7 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF983 PF06170.12 AJA93102.1 - 3.2 8.2 4.6 13 6.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Semialdhyde_dh PF01118.24 AJA93104.1 - 1.7e-34 118.8 0.0 3.1e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AJA93104.1 - 2.6e-18 66.7 0.0 3.8e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 AJA93104.1 - 0.00025 21.2 0.0 0.00054 20.1 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 AJA93104.1 - 0.00038 21.3 0.0 0.00069 20.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 AJA93104.1 - 0.00085 19.6 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 AJA93104.1 - 0.0049 17.4 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 AJA93104.1 - 0.037 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SGP PF17228.2 AJA93104.1 - 0.074 13.9 0.0 0.17 12.7 0.0 1.6 1 0 0 1 1 1 0 Sulphur globule protein NAD_binding_10 PF13460.6 AJA93104.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding Mgr1 PF08602.10 AJA93104.1 - 0.2 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit V_ATPase_I PF01496.19 AJA93105.1 - 3.4e-26 91.4 17.5 2.1e-22 78.9 1.4 3.2 3 0 0 3 3 3 3 V-type ATPase 116kDa subunit family DUF5380 PF17351.2 AJA93105.1 - 0.03 14.2 0.3 0.074 12.9 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5380) DUF948 PF06103.11 AJA93105.1 - 0.096 13.0 5.4 3.4 8.0 0.3 4.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF624 PF04854.14 AJA93105.1 - 0.33 11.1 2.7 1.1 9.5 2.7 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF624 DivIVA PF05103.13 AJA93105.1 - 0.98 9.5 9.3 1.3 9.1 1.3 2.5 2 0 0 2 2 2 0 DivIVA protein DUF1351 PF07083.11 AJA93105.1 - 2.7 7.7 17.2 1.2 8.8 1.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1351) Peptidase_S46 PF10459.9 AJA93105.1 - 3.1 6.3 5.9 3.8 6.0 0.2 1.9 1 1 0 2 2 2 0 Peptidase S46 Trypsin_2 PF13365.6 AJA93106.1 - 2.6e-34 119.3 0.2 4.8e-34 118.4 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AJA93106.1 - 9.4e-18 64.8 0.2 3e-17 63.2 0.2 1.8 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 AJA93106.1 - 8.7e-13 48.4 0.8 3.1e-12 46.7 0.1 2.3 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 AJA93106.1 - 1.5e-06 28.0 2.3 0.023 14.5 0.2 3.0 3 0 0 3 3 3 2 PDZ domain Peptidase_S46 PF10459.9 AJA93106.1 - 5.8e-05 22.0 0.6 0.011 14.4 0.5 2.1 2 0 0 2 2 2 2 Peptidase S46 PDZ PF00595.24 AJA93106.1 - 0.00025 21.3 2.4 0.62 10.5 0.3 3.6 3 0 0 3 3 3 2 PDZ domain Peptidase_S29 PF02907.15 AJA93106.1 - 0.0039 16.9 0.2 0.0099 15.6 0.1 1.8 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Peptidase_S32 PF05579.13 AJA93106.1 - 0.0059 15.8 0.7 0.85 8.8 0.2 2.4 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 Tricorn_PDZ PF14685.6 AJA93106.1 - 0.049 13.6 0.2 0.46 10.5 0.0 2.6 2 1 0 2 2 2 0 Tricorn protease PDZ domain Peptidase_S7 PF00949.21 AJA93106.1 - 0.074 12.9 0.3 0.15 11.9 0.3 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease FAM163 PF15069.6 AJA93107.1 - 0.077 13.4 0.8 0.078 13.4 0.8 1.1 1 0 0 1 1 1 0 FAM163 family Hydrolase PF00702.26 AJA93109.1 - 8.5e-05 22.9 0.0 0.00089 19.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AJA93109.1 - 0.00093 19.3 3.7 0.19 11.8 3.7 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Phage_Nu1 PF07471.12 AJA93109.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Asn_synthase PF00733.21 AJA93111.1 - 4.7e-29 102.2 0.0 3.7e-22 79.5 0.0 2.0 1 1 1 2 2 2 2 Asparagine synthase QueC PF06508.13 AJA93111.1 - 1.2e-06 28.2 0.0 2.3e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 AJA93111.1 - 8.2e-06 25.1 0.4 2e-05 23.8 0.1 1.8 2 1 0 2 2 2 1 NAD synthase tRNA_Me_trans PF03054.16 AJA93111.1 - 0.00064 18.6 0.0 0.0015 17.4 0.0 1.7 1 1 0 1 1 1 1 tRNA methyl transferase ATP_bind_3 PF01171.20 AJA93111.1 - 0.0031 17.3 0.0 0.045 13.5 0.0 2.3 2 1 0 2 2 2 1 PP-loop family ABM PF03992.16 AJA93112.1 - 6.5e-07 29.4 0.0 8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 AJA93112.1 - 0.0023 18.2 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) Putative_PNPOx PF01243.20 AJA93113.1 - 3.2e-16 59.3 0.0 5.6e-16 58.5 0.0 1.4 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 AJA93113.1 - 7e-11 42.3 0.0 9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 AJA93113.1 - 0.00099 18.7 0.1 0.0011 18.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Ribosomal_L34e PF01199.18 AJA93113.1 - 0.014 15.7 0.5 0.021 15.1 0.5 1.2 1 0 0 1 1 1 0 Ribosomal protein L34e LapA_dom PF06305.11 AJA93114.1 - 0.0026 17.5 1.2 0.0037 17.0 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Saf_2TM PF18303.1 AJA93114.1 - 0.0034 17.0 0.4 0.0034 17.0 0.4 1.5 1 1 1 2 2 2 1 SAVED-fused 2TM effector domain DUF308 PF03729.13 AJA93114.1 - 0.12 12.7 8.4 2.1 8.7 8.2 2.0 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Tetraspanin PF00335.20 AJA93114.1 - 0.21 11.3 1.7 0.22 11.2 1.7 1.1 1 0 0 1 1 1 0 Tetraspanin family SPC25 PF06703.11 AJA93114.1 - 0.22 11.3 2.7 0.25 11.1 2.7 1.0 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DNA_pol_B PF00136.21 AJA93115.1 - 4.7e-54 183.8 2.8 8.3e-54 183.0 2.8 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 AJA93115.1 - 7.1e-35 120.7 5.6 1.3e-34 119.9 5.6 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.6 AJA93115.1 - 5.8e-08 32.9 0.5 1.3e-07 31.7 0.5 1.6 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 AJA93115.1 - 1.1e-06 28.5 0.8 5.8e-06 26.1 0.5 2.3 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB E3_UbLigase_RBR PF18091.1 AJA93116.1 - 0.024 14.7 0.1 0.026 14.6 0.1 1.2 1 0 0 1 1 1 0 E3 Ubiquitin Ligase RBR C-terminal domain Amino_oxidase PF01593.24 AJA93117.1 - 4.6e-32 111.9 0.0 1.5e-31 110.2 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AJA93117.1 - 1.2e-12 47.8 0.0 2.3e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AJA93117.1 - 1.4e-08 34.7 0.0 0.00068 19.3 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 AJA93117.1 - 2.3e-07 31.3 1.5 0.0011 19.5 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AJA93117.1 - 1.1e-06 28.2 0.1 0.011 15.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AJA93117.1 - 1.1e-05 24.7 0.2 0.01 15.0 0.5 2.1 2 0 0 2 2 2 2 FAD binding domain MCRA PF06100.11 AJA93117.1 - 3.9e-05 22.6 0.0 9.2e-05 21.4 0.0 1.5 1 1 0 1 1 1 1 MCRA family HI0933_like PF03486.14 AJA93117.1 - 0.00021 20.1 0.0 0.34 9.5 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein GDI PF00996.18 AJA93117.1 - 0.001 17.7 0.5 0.056 12.0 0.1 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor FAD_oxidored PF12831.7 AJA93117.1 - 0.0028 17.0 0.0 0.6 9.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 AJA93117.1 - 0.0093 15.1 0.4 1.4 7.9 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A 3HCDH_N PF02737.18 AJA93117.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 AJA93117.1 - 0.046 12.1 0.0 0.058 11.8 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Thi4 PF01946.17 AJA93117.1 - 0.061 12.5 0.4 0.76 9.0 0.1 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 AJA93117.1 - 0.18 11.8 0.2 0.45 10.5 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding HSP20 PF00011.21 AJA93118.1 - 6.7e-06 26.2 1.1 0.0002 21.5 1.1 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AJA93118.1 - 5.9e-05 22.5 0.0 8.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 AJA93118.1 - 0.00056 20.3 0.0 0.00077 19.8 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain GvpH PF05455.11 AJA93118.1 - 0.035 14.2 0.2 0.042 13.9 0.2 1.2 1 0 0 1 1 1 0 GvpH LMWPc PF01451.21 AJA93119.1 - 3.4e-22 79.4 0.4 1.1e-21 77.7 0.4 1.7 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase LepB_N PF18640.1 AJA93119.1 - 0.034 13.8 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 LepB N-terminal domain Tir_receptor_M PF03549.14 AJA93119.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain Cupin_2 PF07883.11 AJA93120.1 - 6.7e-13 48.2 0.0 8.4e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 Cupin domain CENP-C_C PF11699.8 AJA93120.1 - 6.9e-09 35.8 0.2 9.2e-09 35.4 0.2 1.1 1 0 0 1 1 1 1 Mif2/CENP-C like ARD PF03079.14 AJA93120.1 - 2e-05 24.8 0.0 0.00053 20.2 0.0 2.0 2 0 0 2 2 2 1 ARD/ARD' family AraC_binding PF02311.19 AJA93120.1 - 0.00018 21.4 0.0 0.00027 20.8 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 AJA93120.1 - 0.00058 19.5 0.0 0.00078 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 AJA93120.1 - 0.00067 19.5 0.0 0.0008 19.2 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ DMSP_lyase PF16867.5 AJA93120.1 - 0.0022 17.7 0.0 0.0027 17.4 0.0 1.1 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase Ectoine_synth PF06339.12 AJA93120.1 - 0.017 15.3 0.0 0.023 14.9 0.0 1.3 1 1 0 1 1 1 0 Ectoine synthase Cupin_1 PF00190.22 AJA93120.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Cupin 3-HAO PF06052.12 AJA93120.1 - 0.12 12.0 0.1 0.18 11.5 0.0 1.3 1 1 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Methyltransf_32 PF13679.6 AJA93121.1 - 0.09 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RHH_3 PF12651.7 AJA93121.1 - 0.099 12.6 0.1 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Ribbon-helix-helix domain Methyltransf_25 PF13649.6 AJA93121.1 - 0.17 12.6 0.0 0.32 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain tRNA_synthFbeta PF17759.1 AJA93122.1 - 3.7e-36 124.6 0.1 6.1e-36 123.9 0.1 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 AJA93122.1 - 1.9e-15 56.9 0.1 1.4e-10 41.3 0.0 3.3 3 1 0 3 3 3 2 tRNA synthetase B5 domain B3_4 PF03483.17 AJA93122.1 - 6.1e-14 52.1 0.4 1.1e-13 51.2 0.4 1.4 1 0 0 1 1 1 1 B3/4 domain AIRS_C PF02769.22 AJA93123.1 - 1.8e-23 83.4 0.0 3.5e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AJA93123.1 - 1.4e-15 57.8 0.8 2.6e-15 56.9 0.8 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain CcmH PF03918.14 AJA93124.1 - 0.097 12.0 0.8 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Lyase_1 PF00206.20 AJA93125.1 - 3.6e-45 154.7 0.5 5.6e-45 154.1 0.5 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 AJA93125.1 - 2e-12 47.5 0.0 5.4e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 AJA93125.1 - 0.00046 20.3 0.1 0.0012 19.0 0.1 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal B12-binding PF02310.19 AJA93126.1 - 5.3e-20 71.7 0.1 6.6e-20 71.4 0.1 1.0 1 0 0 1 1 1 1 B12 binding domain IMPDH PF00478.25 AJA93126.1 - 0.0098 14.9 0.1 0.011 14.7 0.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Ocnus PF05005.15 AJA93126.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) Glycos_transf_2 PF00535.26 AJA93127.1 - 6.9e-26 91.1 0.0 9e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AJA93127.1 - 2.7e-10 40.5 0.0 4e-10 40.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AJA93127.1 - 9.2e-05 22.0 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF166 PF02593.14 AJA93127.1 - 0.0013 18.3 0.2 0.0026 17.4 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function CAP59_mtransfer PF11735.8 AJA93127.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 MT-A70 PF05063.14 AJA93127.1 - 0.019 14.9 0.2 0.081 12.8 0.0 2.0 2 0 0 2 2 2 0 MT-A70 RVT_3 PF13456.6 AJA93127.1 - 0.055 13.3 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase-like Ribul_P_3_epim PF00834.19 AJA93127.1 - 0.074 12.4 0.0 0.48 9.8 0.0 2.0 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family Glyco_tranf_2_4 PF13704.6 AJA93127.1 - 0.13 12.8 0.0 0.22 12.0 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 AAA_18 PF13238.6 AJA93128.1 - 3.3e-11 43.8 0.0 5.3e-11 43.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AJA93128.1 - 6.6e-09 36.3 0.0 1.3e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AJA93128.1 - 1.2e-07 32.0 0.1 8.1e-07 29.3 0.1 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family Cytidylate_kin PF02224.18 AJA93128.1 - 9.4e-07 28.8 0.0 0.00023 21.0 0.0 2.2 1 1 1 2 2 2 1 Cytidylate kinase ADK PF00406.22 AJA93128.1 - 2.8e-05 24.3 0.3 9.4e-05 22.6 0.0 2.0 4 0 0 4 4 3 1 Adenylate kinase SKI PF01202.22 AJA93128.1 - 6.6e-05 23.1 0.2 0.00029 21.0 0.2 1.9 1 1 0 1 1 1 1 Shikimate kinase AAA PF00004.29 AJA93128.1 - 0.00012 22.5 0.1 0.00039 20.8 0.2 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AJA93128.1 - 0.00054 20.2 0.0 0.00079 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 AJA93128.1 - 0.00066 20.0 0.0 0.0007 19.9 0.0 1.3 1 1 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 AJA93128.1 - 0.0013 18.9 0.0 0.0024 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 AJA93128.1 - 0.0029 17.1 0.8 0.063 12.7 0.1 2.1 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_24 PF13479.6 AJA93128.1 - 0.0042 16.8 0.0 0.008 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AJA93128.1 - 0.0058 17.0 0.0 0.0095 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase dNK PF01712.19 AJA93128.1 - 0.01 15.7 0.1 0.23 11.3 0.0 2.4 2 1 0 2 2 2 0 Deoxynucleoside kinase RuvB_N PF05496.12 AJA93128.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AJA93128.1 - 0.013 15.8 0.0 0.019 15.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 AJA93128.1 - 0.014 15.3 0.2 0.063 13.2 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 AJA93128.1 - 0.049 12.9 0.1 0.86 8.8 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 AJA93128.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AJA93128.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.21 AJA93128.1 - 0.11 11.8 0.0 9.9 5.5 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Polyketide_cyc2 PF10604.9 AJA93129.1 - 0.089 13.1 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Ribosomal_L30 PF00327.20 AJA93130.1 - 6.7e-11 41.9 0.1 1e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e VPS28 PF03997.12 AJA93130.1 - 0.096 12.4 0.1 11 5.6 0.0 2.1 1 1 1 2 2 2 0 VPS28 protein Ribosomal_S9 PF00380.19 AJA93133.1 - 1.9e-31 109.1 0.2 2.2e-31 108.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L29 PF00831.23 AJA93134.1 - 3.5e-12 46.1 7.8 4.3e-12 45.8 7.8 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein DUF1192 PF06698.11 AJA93134.1 - 0.0054 16.8 4.1 0.028 14.4 0.6 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.6 AJA93134.1 - 0.0069 16.8 5.4 0.0082 16.5 5.4 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Ran-binding PF05508.11 AJA93134.1 - 0.026 13.5 2.7 0.029 13.4 2.7 1.0 1 0 0 1 1 1 0 RanGTP-binding protein PilJ PF13675.6 AJA93134.1 - 0.028 14.4 0.1 0.028 14.4 0.1 1.0 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term FemAB PF02388.16 AJA93134.1 - 0.16 10.8 3.2 0.17 10.8 3.2 1.0 1 0 0 1 1 1 0 FemAB family GTP-bdg_M PF16360.5 AJA93134.1 - 0.49 11.0 7.9 0.5 11.0 1.5 2.1 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region Tetraspanin PF00335.20 AJA93136.1 - 0.0057 16.4 0.3 0.0064 16.2 0.3 1.0 1 0 0 1 1 1 1 Tetraspanin family YtpI PF14007.6 AJA93136.1 - 0.011 15.9 2.3 0.15 12.2 0.4 2.1 2 0 0 2 2 2 0 YtpI-like protein DUF3784 PF12650.7 AJA93136.1 - 0.047 13.9 5.2 2.4 8.4 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Neurensin PF14927.6 AJA93136.1 - 0.07 12.8 0.2 0.12 12.1 0.2 1.4 1 1 0 1 1 1 0 Neurensin DUF3185 PF11381.8 AJA93136.1 - 0.38 10.8 4.7 3 7.9 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) Saf_2TM PF18303.1 AJA93136.1 - 2.1 7.9 5.3 3 7.4 1.6 2.0 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain TatD_DNase PF01026.21 AJA93137.1 - 5.1e-45 153.8 0.0 5.8e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_1 PF01979.20 AJA93137.1 - 0.032 13.6 0.0 0.4 9.9 0.0 2.0 1 1 0 1 1 1 0 Amidohydrolase family NTP_transf_3 PF12804.7 AJA93138.1 - 1.5e-16 61.1 0.0 1.8e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AJA93138.1 - 1.4e-10 41.3 0.0 1.9e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transferase PF00483.23 AJA93138.1 - 0.00035 20.2 0.1 0.0006 19.5 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase CTP_transf_3 PF02348.19 AJA93138.1 - 0.00084 19.3 0.2 0.0038 17.2 0.2 2.0 1 1 0 1 1 1 1 Cytidylyltransferase CofC PF01983.16 AJA93138.1 - 0.0042 16.3 0.8 0.0042 16.3 0.8 1.6 2 0 0 2 2 2 1 Guanylyl transferase CofC like DUF4851 PF16143.5 AJA93138.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4851) IMPDH PF00478.25 AJA93140.1 - 6.4e-146 485.8 7.3 7.3e-146 485.6 7.3 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 AJA93140.1 - 7.9e-22 77.5 2.1 9.1e-11 42.0 0.2 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 AJA93140.1 - 4.6e-10 39.4 5.7 7e-06 25.6 3.6 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 AJA93140.1 - 4.7e-06 25.9 7.2 9.1e-06 24.9 7.2 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 AJA93140.1 - 1.9e-05 24.3 3.7 0.0043 16.5 0.1 3.0 1 1 2 3 3 3 2 Histidine biosynthesis protein DHO_dh PF01180.21 AJA93140.1 - 0.00028 20.2 0.6 0.00028 20.2 0.6 2.0 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 AJA93140.1 - 0.017 14.5 3.1 0.018 14.3 0.2 2.2 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 AJA93140.1 - 0.048 12.8 4.0 0.088 11.9 4.0 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase PEP_mutase PF13714.6 AJA93140.1 - 0.069 12.6 0.5 0.15 11.5 0.2 1.7 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase MMR_HSR1_Xtn PF16897.5 AJA93141.1 - 8.5e-29 99.7 2.9 1.8e-28 98.6 2.9 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 AJA93141.1 - 4e-23 81.7 0.0 1.3e-22 80.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 AJA93141.1 - 2.9e-21 75.3 0.1 1.1e-20 73.5 0.0 2.0 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 AJA93141.1 - 2e-16 59.9 4.4 9.5e-14 51.2 0.2 2.6 3 0 0 3 3 3 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AJA93141.1 - 2.7e-07 30.6 3.2 0.00069 19.6 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 AJA93141.1 - 0.00023 21.2 4.4 0.089 12.8 0.4 3.1 2 1 0 3 3 3 2 Dynamin family Arf PF00025.21 AJA93141.1 - 0.0019 17.7 1.6 0.12 11.9 0.1 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 AJA93141.1 - 0.0065 15.9 0.1 0.0065 15.9 0.1 2.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.22 AJA93141.1 - 0.0074 15.9 6.3 0.082 12.5 0.4 2.7 3 0 0 3 3 3 2 Ras family MeaB PF03308.16 AJA93141.1 - 0.022 13.7 0.5 0.13 11.2 0.3 2.2 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 AJA93141.1 - 0.033 14.4 0.5 0.18 12.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 AJA93141.1 - 0.079 13.2 0.5 0.28 11.4 0.0 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 AJA93141.1 - 0.087 13.1 0.3 0.087 13.1 0.3 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AJA93141.1 - 0.11 12.8 0.4 0.61 10.5 0.1 2.3 2 1 0 3 3 2 0 AAA ATPase domain GSHPx PF00255.19 AJA93141.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase Epimerase PF01370.21 AJA93142.1 - 2.3e-30 105.8 0.0 3e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJA93142.1 - 2.7e-24 86.2 0.1 1.2e-23 84.1 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AJA93142.1 - 1.3e-18 67.1 0.0 1.8e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AJA93142.1 - 1.9e-15 56.8 0.1 2.7e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AJA93142.1 - 8.3e-14 51.2 0.1 1.2e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AJA93142.1 - 5.8e-07 29.6 0.0 8.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 AJA93142.1 - 2.9e-06 27.6 0.0 8.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 AJA93142.1 - 2.6e-05 23.5 0.5 0.00086 18.6 0.5 2.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 AJA93142.1 - 0.00016 21.6 0.0 0.00054 19.9 0.0 1.8 1 1 0 1 1 1 1 KR domain Mesothelin PF06060.12 AJA93142.1 - 0.0036 15.6 0.0 0.005 15.1 0.0 1.1 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) NmrA PF05368.13 AJA93142.1 - 0.0096 15.5 0.0 0.016 14.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 AJA93142.1 - 0.018 15.1 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 AJA93142.1 - 0.038 14.7 0.0 0.28 11.9 0.0 2.4 3 0 0 3 3 2 0 Methyltransferase domain adh_short PF00106.25 AJA93142.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Ribosomal_S25 PF03297.15 AJA93143.1 - 1.5e-09 38.0 5.9 1.6e-09 37.9 5.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR PF01047.22 AJA93143.1 - 0.0041 17.0 0.1 0.0041 17.0 0.1 1.8 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 AJA93143.1 - 0.0046 16.5 0.1 0.0062 16.1 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding LacI PF00356.21 AJA93143.1 - 0.0082 15.9 0.1 0.016 15.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family TrmB PF01978.19 AJA93143.1 - 0.013 15.3 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SID-1_RNA_chan PF13965.6 AJA93143.1 - 0.033 12.6 2.8 0.035 12.5 2.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF977 PF06163.11 AJA93143.1 - 0.047 13.6 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) MarR_2 PF12802.7 AJA93143.1 - 0.097 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 MarR family RVT_3 PF13456.6 AJA93144.1 - 0.054 13.3 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like UDPG_MGDP_dh_N PF03721.14 AJA93145.1 - 1.4e-40 138.9 0.3 3.3e-40 137.7 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 AJA93145.1 - 3.9e-22 78.7 0.0 2.2e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 AJA93145.1 - 3.4e-21 75.2 0.1 6.6e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 2-Hacid_dh_C PF02826.19 AJA93145.1 - 2.8e-06 26.8 0.1 0.081 12.3 0.0 3.2 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AJA93145.1 - 0.00012 22.3 0.0 0.00047 20.4 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AJA93145.1 - 0.00036 20.5 0.1 0.01 15.8 0.0 2.9 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DpaA_N PF16924.5 AJA93145.1 - 0.0032 17.5 0.8 4.6 7.4 0.1 3.2 3 0 0 3 3 3 2 Dipicolinate synthase subunit A N-terminal domain 3HCDH_N PF02737.18 AJA93145.1 - 0.0036 17.2 0.0 0.0094 15.8 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 AJA93145.1 - 0.0054 17.0 0.2 0.011 16.0 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ApbA PF02558.16 AJA93145.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 AJA93145.1 - 0.072 13.4 0.2 1.1 9.6 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain ThiF PF00899.21 AJA93145.1 - 0.082 12.3 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 ThiF family Peptidase_S24 PF00717.23 AJA93146.1 - 6.1e-07 29.3 0.3 6.1e-07 29.3 0.3 2.0 2 0 0 2 2 2 1 Peptidase S24-like TrbC PF04956.13 AJA93146.1 - 0.0091 16.2 4.9 0.028 14.6 0.8 2.2 2 0 0 2 2 2 1 TrbC/VIRB2 family MscL PF01741.18 AJA93146.1 - 0.012 15.9 0.5 0.028 14.7 0.0 1.9 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL Ureide_permease PF07168.11 AJA93146.1 - 0.023 13.5 0.1 0.034 12.9 0.1 1.2 1 0 0 1 1 1 0 Ureide permease Sigma_reg_N PF13800.6 AJA93146.1 - 0.14 12.4 2.1 0.59 10.5 0.1 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal SID-1_RNA_chan PF13965.6 AJA93146.1 - 0.17 10.2 0.4 0.23 9.8 0.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 AJA93146.1 - 0.29 12.1 5.8 0.25 12.3 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) GTP_EFTU PF00009.27 AJA93147.1 - 1.1e-59 201.2 0.6 1.9e-59 200.5 0.6 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AJA93147.1 - 2.9e-22 78.5 0.0 1e-21 76.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 AJA93147.1 - 8e-21 73.9 0.7 1.9e-20 72.7 0.7 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 AJA93147.1 - 1.7e-18 66.5 0.0 1.3e-17 63.7 0.0 2.4 1 1 1 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 AJA93147.1 - 1.3e-13 51.1 0.2 3.9e-13 49.6 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AJA93147.1 - 0.00098 19.2 0.0 0.0026 17.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase E3_UbLigase_EDD PF11547.8 AJA93147.1 - 0.16 11.7 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD Fe-S_biosyn PF01521.20 AJA93148.1 - 1.2e-22 80.2 0.0 1.6e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis GTP_EFTU PF00009.27 AJA93149.1 - 5.1e-46 156.7 0.0 7e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AJA93149.1 - 4e-35 120.5 0.1 8.6e-35 119.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AJA93149.1 - 1.5e-16 60.5 0.2 6.2e-16 58.5 0.2 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 AJA93149.1 - 1.5e-05 24.8 0.8 4e-05 23.4 0.8 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 NIF3 PF01784.18 AJA93149.1 - 0.013 15.1 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) MMR_HSR1 PF01926.23 AJA93149.1 - 0.082 13.0 0.0 0.4 10.8 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase DHQS PF01959.16 AJA93150.1 - 1.1e-104 350.2 1.9 1.2e-104 350.0 1.9 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase II HSDR_N PF04313.14 AJA93151.1 - 0.031 14.2 0.8 0.035 14.0 0.8 1.0 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF1874 PF08960.10 AJA93151.1 - 0.036 14.2 0.6 0.041 14.0 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) AF0941-like PF14591.6 AJA93151.1 - 0.044 14.3 2.5 0.049 14.2 2.5 1.1 1 0 0 1 1 1 0 AF0941-like zf-AN1 PF01428.16 AJA93153.1 - 3e-11 43.3 6.7 4.5e-11 42.7 6.7 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 AJA93153.1 - 0.29 11.5 4.6 1.4 9.3 4.6 1.9 1 1 0 1 1 1 0 Tc5 transposase C-terminal domain zf-C2H2_4 PF13894.6 AJA93153.1 - 0.47 11.4 5.3 0.52 11.3 1.8 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger PSI_integrin PF17205.3 AJA93153.1 - 0.71 9.7 6.2 0.71 9.7 0.9 2.1 1 1 1 2 2 2 0 Integrin plexin domain DFP PF04127.15 AJA93154.1 - 3e-57 193.5 5.1 8.4e-56 188.7 5.4 2.3 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 AJA93154.1 - 5.7e-34 117.1 0.3 5.7e-34 117.1 0.3 2.2 2 1 0 2 2 2 1 Flavoprotein NAD_binding_7 PF13241.6 AJA93154.1 - 0.0017 18.7 1.3 0.079 13.4 0.2 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_10 PF13460.6 AJA93154.1 - 0.075 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Glyco_trans_4_5 PF16994.5 AJA93154.1 - 0.077 12.6 1.3 0.21 11.2 0.3 2.2 2 1 0 2 2 2 0 Glycosyl-transferase family 4 Ribosomal_L1 PF00687.21 AJA93155.1 - 2.5e-41 141.7 0.9 3e-41 141.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family IGPD PF00475.18 AJA93155.1 - 0.095 13.0 0.1 0.44 10.8 0.0 2.0 1 1 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase PTPS PF01242.19 AJA93156.1 - 2.1e-24 85.8 0.0 2.3e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase CAAP1 PF15335.6 AJA93156.1 - 0.067 13.8 0.2 0.12 12.9 0.2 1.4 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 VWA PF00092.28 AJA93157.1 - 8.5e-05 22.9 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain GerPC PF10737.9 AJA93157.1 - 0.02 15.0 0.4 0.043 13.9 0.4 1.5 1 0 0 1 1 1 0 Spore germination protein GerPC Myb_DNA-bind_2 PF08914.11 AJA93157.1 - 0.024 14.8 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 Rap1 Myb domain VWA_3 PF13768.6 AJA93157.1 - 0.04 13.9 0.0 0.12 12.3 0.0 1.8 3 0 0 3 3 3 0 von Willebrand factor type A domain vWA-TerF-like PF10138.9 AJA93157.1 - 0.056 13.6 0.2 2.1 8.4 0.0 2.9 2 1 0 2 2 2 0 vWA found in TerF C terminus DUF1418 PF07214.12 AJA93159.1 - 0.54 10.2 2.6 1.7 8.5 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) DUF4118 PF13493.6 AJA93159.1 - 7.2 6.5 11.3 0.91 9.4 6.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) DUF2383 PF09537.10 AJA93160.1 - 0.004 17.5 0.0 0.0074 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) AMO PF02461.16 AJA93160.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Ammonia monooxygenase TSC22 PF01166.18 AJA93160.1 - 0.15 12.3 1.8 0.31 11.4 1.8 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family ADH_N PF08240.12 AJA93161.1 - 1.4e-21 76.4 1.9 3e-21 75.3 1.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AJA93161.1 - 1.6e-18 66.9 0.1 2.4e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AJA93161.1 - 2.6e-13 50.0 0.2 4.2e-13 49.3 0.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 AJA93161.1 - 7.7e-06 27.0 0.2 1.4e-05 26.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TMEM154 PF15102.6 AJA93162.1 - 0.019 14.9 1.0 0.03 14.2 1.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF1664 PF07889.12 AJA93162.1 - 0.2 11.7 0.2 0.6 10.2 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AmoC PF04896.12 AJA93163.1 - 1.1e-12 47.8 6.6 1.4e-12 47.5 6.6 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C RTA1 PF04479.13 AJA93163.1 - 0.0051 16.4 0.3 0.0075 15.9 0.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Pro_isomerase PF00160.21 AJA93164.1 - 2.7e-51 174.0 0.0 3e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AAA_18 PF13238.6 AJA93165.1 - 1.7e-10 41.5 0.5 2.8e-10 40.8 0.1 1.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 AJA93165.1 - 0.035 14.2 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 AJA93165.1 - 0.038 13.9 0.1 0.26 11.2 0.0 2.1 2 1 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 AJA93165.1 - 0.042 13.6 0.1 0.088 12.5 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 AJA93165.1 - 0.061 13.7 0.4 0.2 12.1 0.4 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AJA93165.1 - 0.088 13.1 0.0 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 AJA93165.1 - 0.09 12.5 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain NHL PF01436.21 AJA93166.1 - 0.014 15.4 0.1 0.055 13.5 0.1 2.0 2 0 0 2 2 2 0 NHL repeat PDZ PF00595.24 AJA93166.1 - 0.071 13.5 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Cupredoxin_1 PF13473.6 AJA93166.1 - 0.085 13.0 0.0 0.33 11.1 0.0 2.0 2 1 0 2 2 2 0 Cupredoxin-like domain Copper-bind PF00127.20 AJA93166.1 - 0.095 13.2 0.0 0.62 10.5 0.0 2.2 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Sulfotransfer_1 PF00685.27 AJA93168.1 - 3.5e-22 79.2 1.9 4.5e-22 78.8 1.9 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 AJA93168.1 - 2.8e-10 41.0 0.0 2.6e-07 31.2 0.0 2.9 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 AJA93168.1 - 0.00026 21.0 1.6 0.00065 19.7 1.6 1.6 1 1 0 1 1 1 1 Sulfotransferase family SRPRB PF09439.10 AJA93168.1 - 0.017 14.6 0.0 0.041 13.3 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 AJA93168.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Radical_SAM PF04055.21 AJA93169.1 - 2.9e-19 70.0 0.0 2.9e-18 66.8 0.0 2.2 2 1 0 2 2 2 1 Radical SAM superfamily BKACE PF05853.12 AJA93169.1 - 0.00074 18.9 0.0 0.044 13.1 0.0 2.3 2 1 0 2 2 2 2 beta-keto acid cleavage enzyme Fer4_14 PF13394.6 AJA93169.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain Thioredoxin_4 PF13462.6 AJA93170.1 - 3.2e-31 108.7 0.1 4.1e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AJA93170.1 - 7.5e-17 61.7 0.1 1.5e-15 57.5 0.1 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJA93170.1 - 1.8e-14 54.1 0.1 2.9e-14 53.4 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 AJA93170.1 - 3.9e-06 26.7 0.1 8e-06 25.7 0.0 1.5 1 1 1 2 2 2 1 Thioredoxin Thioredoxin PF00085.20 AJA93170.1 - 0.02 14.9 0.0 0.85 9.6 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_8 PF13905.6 AJA93170.1 - 0.14 12.5 0.9 1.7 9.1 0.6 2.3 2 1 0 2 2 2 0 Thioredoxin-like Ammonium_transp PF00909.21 AJA93171.1 - 3.6e-111 371.7 31.4 4e-111 371.5 31.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Thioredoxin PF00085.20 AJA93172.1 - 2.3e-31 107.9 0.1 3.2e-31 107.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AJA93172.1 - 2.1e-08 34.4 0.6 2.9e-06 27.5 0.0 2.6 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.6 AJA93172.1 - 3.7e-08 33.2 0.4 4.6e-08 32.9 0.4 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AJA93172.1 - 5.3e-08 33.3 0.2 2.4e-07 31.2 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 AJA93172.1 - 1.5e-06 27.8 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 AJA93172.1 - 4e-05 23.6 0.2 0.00016 21.7 0.0 2.0 2 1 1 3 3 3 1 Thioredoxin domain Phosducin PF02114.16 AJA93172.1 - 0.00017 20.6 0.0 0.0002 20.4 0.0 1.0 1 0 0 1 1 1 1 Phosducin Redoxin PF08534.10 AJA93172.1 - 0.0002 21.1 0.1 0.00075 19.2 0.1 1.7 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 AJA93172.1 - 0.00082 19.3 0.1 0.0024 17.8 0.1 1.8 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 AJA93172.1 - 0.0017 18.2 0.1 0.0028 17.5 0.1 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 AJA93172.1 - 0.013 15.7 0.3 0.031 14.4 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 AJA93172.1 - 0.038 14.0 0.1 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DUF836 PF05768.14 AJA93172.1 - 0.039 14.4 0.1 0.21 12.0 0.0 2.0 1 1 1 2 2 2 0 Glutaredoxin-like domain (DUF836) Pribosyltran PF00156.27 AJA93173.1 - 4.3e-12 45.8 0.3 5.9e-12 45.4 0.3 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 AJA93173.1 - 0.05 13.1 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Thioredoxin_4 PF13462.6 AJA93174.1 - 4.5e-29 101.8 0.0 5.4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AJA93174.1 - 2e-09 37.5 0.3 8.7e-08 32.2 0.3 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJA93174.1 - 3.3e-07 30.7 0.0 5.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 AJA93174.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 AJA93174.1 - 0.031 14.6 0.0 2.1 8.7 0.0 2.3 1 1 0 1 1 1 0 Thioredoxin-like Autophagy_N PF03986.13 AJA93174.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain PIN_9 PF18477.1 AJA93176.1 - 2.3e-14 53.7 0.2 2.8e-14 53.4 0.2 1.0 1 0 0 1 1 1 1 PIN like domain Fcf1 PF04900.12 AJA93176.1 - 1.3e-05 25.5 0.0 1.7e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Fcf1 PIN_4 PF13638.6 AJA93176.1 - 0.044 14.1 2.5 0.074 13.3 2.5 1.4 1 1 0 1 1 1 0 PIN domain HypA PF01155.19 AJA93176.1 - 0.053 13.5 0.0 0.083 12.9 0.0 1.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF5615 PF18480.1 AJA93176.1 - 0.082 12.7 0.2 0.15 11.8 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5615) Imm43 PF15570.6 AJA93176.1 - 0.11 12.5 1.1 0.88 9.6 0.2 2.2 1 1 1 2 2 2 0 Immunity protein 43 AhpC-TSA PF00578.21 AJA93177.1 - 6.8e-06 26.0 0.1 0.00094 19.1 0.0 2.5 2 1 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 AJA93177.1 - 7e-06 25.8 0.0 0.0055 16.4 0.0 2.3 1 1 1 2 2 2 2 Redoxin Thioredoxin_8 PF13905.6 AJA93177.1 - 0.015 15.6 0.0 5.4 7.4 0.0 2.6 2 1 0 2 2 2 0 Thioredoxin-like DZR PF12773.7 AJA93178.1 - 0.00021 21.2 0.5 0.00026 21.0 0.5 1.1 1 0 0 1 1 1 1 Double zinc ribbon zf_UBZ PF18439.1 AJA93178.1 - 0.00066 19.2 1.2 0.69 9.6 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-TFIIB PF13453.6 AJA93178.1 - 0.0013 18.0 0.8 0.0071 15.6 0.2 2.0 2 0 0 2 2 2 1 Transcription factor zinc-finger Chordopox_RPO7 PF05864.12 AJA93178.1 - 0.0016 18.7 1.9 0.0039 17.4 1.8 1.7 1 1 1 2 2 2 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) TF_Zn_Ribbon PF08271.12 AJA93178.1 - 0.0021 17.5 1.1 0.098 12.2 0.1 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 AJA93178.1 - 0.0025 17.1 3.2 0.77 9.3 0.4 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zf-LITAF-like PF10601.9 AJA93178.1 - 0.0046 17.2 3.0 0.29 11.4 0.5 2.1 1 1 1 2 2 2 1 LITAF-like zinc ribbon domain zf-ACC PF17848.1 AJA93178.1 - 0.0049 16.9 3.9 0.022 14.8 0.1 2.5 3 0 0 3 3 3 1 Acetyl-coA carboxylase zinc finger domain LIM PF00412.22 AJA93178.1 - 0.008 16.4 0.2 0.012 15.9 0.2 1.3 1 1 0 1 1 1 1 LIM domain HypA PF01155.19 AJA93178.1 - 0.013 15.5 0.4 0.014 15.4 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 AJA93178.1 - 0.025 14.3 3.8 1.5 8.6 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 AJA93178.1 - 0.027 14.4 1.6 10 6.2 0.1 2.0 1 1 0 1 1 1 0 zinc-ribbons DUF4428 PF14471.6 AJA93178.1 - 0.029 14.3 3.2 0.15 12.0 1.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) Zn-ribbon_8 PF09723.10 AJA93178.1 - 0.032 14.3 1.3 0.087 13.0 1.3 1.7 1 1 0 1 1 1 0 Zinc ribbon domain SR1P PF13790.6 AJA93178.1 - 0.033 14.3 0.5 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 SR1 protein zf-C3HC4_3 PF13920.6 AJA93178.1 - 0.058 13.3 2.9 0.42 10.5 2.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 AJA93178.1 - 0.075 13.1 2.0 0.47 10.6 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-Di19 PF05605.12 AJA93178.1 - 0.076 13.3 1.3 1.5 9.1 0.1 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DiS_P_DiS PF06750.13 AJA93178.1 - 0.13 12.4 1.9 4.9 7.3 0.3 2.0 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-C2HC5 PF06221.13 AJA93178.1 - 0.16 11.9 3.8 0.46 10.5 3.8 1.7 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-BED PF02892.15 AJA93178.1 - 0.21 11.6 5.0 1.6 8.8 2.5 2.1 1 1 1 2 2 2 0 BED zinc finger zf-C2H2 PF00096.26 AJA93178.1 - 0.23 12.0 4.0 3.8 8.2 0.2 2.3 2 1 0 2 2 2 0 Zinc finger, C2H2 type YhfH PF14149.6 AJA93178.1 - 0.25 11.4 4.2 4.5 7.3 0.8 2.3 2 0 0 2 2 2 0 YhfH-like protein zf-C2H2_4 PF13894.6 AJA93178.1 - 0.33 11.9 4.8 3.8 8.6 0.5 2.7 1 1 1 2 2 2 0 C2H2-type zinc finger Minor_capsid_2 PF11114.8 AJA93179.1 - 0.043 13.8 0.7 0.1 12.6 0.7 1.6 1 0 0 1 1 1 0 Minor capsid protein Polysacc_synt_C PF14667.6 AJA93180.1 - 0.0002 21.5 11.1 0.0002 21.5 11.1 4.4 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Polysacc_synt_3 PF13440.6 AJA93180.1 - 0.75 8.9 35.9 1.7 7.8 18.0 2.8 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 AJA93180.1 - 0.76 9.1 46.0 0.17 11.3 25.2 2.9 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein SNARE_assoc PF09335.11 AJA93181.1 - 1e-14 55.0 3.6 1e-14 55.0 3.6 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein Glycophorin_A PF01102.18 AJA93181.1 - 0.11 12.8 1.6 0.64 10.3 0.2 2.1 2 0 0 2 2 2 0 Glycophorin A IBR PF01485.21 AJA93183.1 - 0.0017 18.6 1.5 0.0017 18.6 1.5 1.4 2 0 0 2 2 1 1 IBR domain, a half RING-finger domain CpXC PF14353.6 AJA93183.1 - 0.0039 17.2 2.6 0.059 13.4 0.2 2.0 1 1 1 2 2 2 1 CpXC protein Auto_anti-p27 PF06677.12 AJA93183.1 - 0.0075 16.4 2.5 0.013 15.6 2.5 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HypA PF01155.19 AJA93183.1 - 0.015 15.3 0.5 0.016 15.2 0.5 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS91 PF14319.6 AJA93183.1 - 0.016 15.3 0.3 0.017 15.1 0.3 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain zinc_ribbon_4 PF13717.6 AJA93183.1 - 0.018 15.0 5.4 0.65 10.0 5.4 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 AJA93183.1 - 0.019 14.4 2.1 2.5 7.6 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_S27e PF01667.17 AJA93183.1 - 0.02 14.6 2.0 0.069 12.9 1.8 1.8 1 1 1 2 2 2 0 Ribosomal protein S27 zf-DNL PF05180.12 AJA93183.1 - 0.028 14.4 0.8 5.1 7.1 0.1 2.0 1 1 1 2 2 2 0 DNL zinc finger Anti-TRAP PF15777.5 AJA93183.1 - 0.03 14.3 0.3 0.046 13.7 0.3 1.2 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein OrfB_Zn_ribbon PF07282.11 AJA93183.1 - 0.033 14.1 1.6 0.046 13.6 1.6 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain YacG PF03884.14 AJA93183.1 - 0.04 13.6 1.1 3.4 7.5 0.1 2.2 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-RING_7 PF02591.15 AJA93183.1 - 0.067 13.4 2.8 1.5 9.0 0.1 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain DUF2614 PF11023.8 AJA93183.1 - 0.067 13.3 0.5 0.074 13.1 0.5 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain PhnA_Zn_Ribbon PF08274.12 AJA93183.1 - 0.095 12.7 2.3 1.4 9.0 0.1 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-ISL3 PF14690.6 AJA93183.1 - 0.11 13.2 4.6 4.2 8.1 0.5 2.1 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.7 AJA93183.1 - 0.11 12.4 5.6 0.43 10.6 0.5 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.6 AJA93183.1 - 0.12 12.1 2.8 0.25 11.1 2.8 1.5 1 1 0 1 1 1 0 zinc-ribbon domain DUF4830 PF16112.5 AJA93183.1 - 0.13 12.8 0.0 0.16 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4830) tRNA-synt_1g PF09334.11 AJA93183.1 - 0.13 11.0 0.4 0.15 10.8 0.4 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) Ogr_Delta PF04606.12 AJA93183.1 - 0.17 11.9 2.8 3.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Thioredoxin_3 PF13192.6 AJA93183.1 - 0.21 11.7 2.4 9.5 6.3 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin domain DUF3797 PF12677.7 AJA93183.1 - 0.27 11.2 5.6 1.9 8.4 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) Zn-ribbon_8 PF09723.10 AJA93183.1 - 0.45 10.7 6.0 3.5 7.8 6.1 2.0 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 AJA93183.1 - 0.61 10.4 5.9 1.2 9.5 0.4 2.2 1 1 1 2 2 2 0 zinc-ribbon Aminotran_5 PF00266.19 AJA93184.1 - 9.9e-153 508.5 0.2 1.1e-152 508.3 0.2 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AJA93184.1 - 0.00034 19.3 0.1 0.00061 18.4 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AJA93184.1 - 0.0014 18.0 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.13 AJA93184.1 - 0.0057 15.7 0.0 0.0093 15.0 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Prenyltransf PF01255.19 AJA93185.1 - 1.2e-70 237.6 0.1 1.3e-70 237.4 0.1 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Seryl_tRNA_N PF02403.22 AJA93185.1 - 0.062 13.5 0.5 0.12 12.6 0.4 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PIN_12 PF16289.5 AJA93185.1 - 0.076 13.5 2.3 0.14 12.6 0.8 1.9 1 1 1 2 2 2 0 PIN domain Cob_adeno_trans PF01923.18 AJA93185.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF1899 PF08953.11 AJA93186.1 - 0.077 12.9 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) TAL_FSA PF00923.19 AJA93187.1 - 1.5e-58 198.5 0.1 1.4e-57 195.3 0.1 2.2 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase FMN_dh PF01070.18 AJA93187.1 - 0.0013 17.8 0.1 0.0014 17.8 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TGT PF01702.18 AJA93187.1 - 0.053 12.7 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase Glyoxalase_4 PF13669.6 AJA93188.1 - 3e-24 85.4 0.0 3.4e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 AJA93188.1 - 1.7e-12 47.6 0.0 1.8e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AJA93188.1 - 7.2e-10 39.2 0.0 7.5e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AJA93188.1 - 0.00072 20.3 0.0 0.00093 20.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain DDE_Tnp_ISL3 PF01610.17 AJA93188.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Transposase DUF5305 PF17231.2 AJA93189.1 - 0.041 13.3 0.4 1.4 8.2 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Trypan_PARP PF05887.11 AJA93189.1 - 0.11 12.5 7.6 0.19 11.7 7.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_ligase_A_M PF01068.21 AJA93190.1 - 5.8e-57 192.6 2.0 5.8e-57 192.6 2.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 AJA93190.1 - 1.3e-39 136.2 1.5 1.3e-39 136.2 1.5 2.2 2 1 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 AJA93190.1 - 1e-20 74.1 0.0 2e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 AJA93190.1 - 2.8e-09 37.5 0.2 5.1e-09 36.6 0.2 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 AJA93190.1 - 0.085 12.9 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 DNA ligase OB-like domain SIS_2 PF13580.6 AJA93191.1 - 3.6e-20 72.4 0.1 4.7e-20 72.0 0.1 1.1 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 AJA93191.1 - 2.4e-11 43.6 0.2 1.6e-09 37.7 0.1 2.2 2 0 0 2 2 2 2 SIS domain Hydrolase_6 PF13344.6 AJA93191.1 - 0.0043 17.1 0.2 0.38 10.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase MAF_flag10 PF01973.18 AJA93191.1 - 0.029 14.1 0.1 0.4 10.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF115 PhoU PF01895.19 AJA93192.1 - 2.2e-18 66.5 10.5 6.3e-17 61.8 1.1 2.6 2 0 0 2 2 2 2 PhoU domain MazE_antitoxin PF04014.18 AJA93192.1 - 2.5e-06 27.3 0.0 7.9e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin Syntaxin_2 PF14523.6 AJA93192.1 - 0.31 11.4 5.7 9 6.7 4.1 3.4 2 1 0 2 2 2 0 Syntaxin-like protein Aminotran_5 PF00266.19 AJA93193.1 - 1.5e-31 109.7 0.0 1.9e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AJA93193.1 - 0.025 13.1 0.1 0.037 12.6 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Radical_SAM PF04055.21 AJA93194.1 - 1.2e-10 42.0 0.0 2.6e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily PGK PF00162.19 AJA93195.1 - 1e-100 337.3 0.8 1.2e-100 337.1 0.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Fe_dep_repress PF01325.19 AJA93196.1 - 5.8e-18 64.8 1.4 7.4e-18 64.5 0.7 1.6 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.15 AJA93196.1 - 1e-17 63.9 0.2 2.4e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain HTH_6 PF01418.17 AJA93196.1 - 3.6e-05 23.7 0.0 0.0015 18.4 0.0 2.4 1 1 1 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_27 PF13463.6 AJA93196.1 - 0.00017 22.0 0.0 0.0014 19.1 0.0 2.2 2 0 0 2 2 2 1 Winged helix DNA-binding domain LexA_DNA_bind PF01726.16 AJA93196.1 - 0.00018 21.2 0.0 0.0037 17.0 0.0 2.7 3 1 0 3 3 3 1 LexA DNA binding domain MarR_2 PF12802.7 AJA93196.1 - 0.00027 20.8 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AJA93196.1 - 0.00041 20.2 0.0 0.00082 19.3 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_12 PF08461.10 AJA93196.1 - 0.0026 17.7 0.0 0.006 16.5 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain TrmB PF01978.19 AJA93196.1 - 0.0029 17.5 0.1 0.0054 16.6 0.1 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF2683 PF10884.8 AJA93196.1 - 0.0048 17.1 1.6 0.15 12.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2683) DUF2250 PF10007.9 AJA93196.1 - 0.0049 17.0 0.1 0.0084 16.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_45 PF14947.6 AJA93196.1 - 0.005 16.8 0.4 0.0089 16.0 0.4 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_Crp_2 PF13545.6 AJA93196.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DUF2624 PF11116.8 AJA93196.1 - 0.0087 16.9 0.2 0.033 15.1 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2624) WYL_3 PF18488.1 AJA93196.1 - 0.041 14.2 0.6 0.37 11.2 0.2 2.3 2 0 0 2 2 2 0 WYL domain TRM PF02005.16 AJA93196.1 - 0.069 12.3 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase HTH_5 PF01022.20 AJA93196.1 - 0.085 12.7 0.1 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Methyltransf_31 PF13847.6 AJA93197.1 - 2.3e-16 59.9 0.1 3.2e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AJA93197.1 - 6.3e-14 52.2 0.4 7.9e-14 51.9 0.4 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 AJA93197.1 - 1.5e-11 44.8 0.0 3.1e-11 43.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AJA93197.1 - 5.8e-11 42.3 2.0 7.6e-11 41.9 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 AJA93197.1 - 1.9e-10 40.5 0.2 3.5e-10 39.6 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 AJA93197.1 - 5.6e-09 36.1 0.7 7.4e-09 35.7 0.7 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJA93197.1 - 3e-08 34.3 0.1 6.9e-08 33.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 AJA93197.1 - 5.5e-08 32.5 0.0 9.5e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 AJA93197.1 - 9.1e-08 31.7 0.1 1.3e-07 31.2 0.1 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 AJA93197.1 - 1e-07 32.5 0.0 1.9e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 AJA93197.1 - 3.2e-07 29.7 0.1 3.8e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Cons_hypoth95 PF03602.15 AJA93197.1 - 6.7e-07 29.1 0.0 1.1e-06 28.5 0.0 1.5 1 1 1 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 AJA93197.1 - 7e-07 28.9 0.1 1.8e-06 27.6 0.1 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.6 AJA93197.1 - 1.6e-06 28.1 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 AJA93197.1 - 1.9e-05 24.3 0.2 4e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.6 AJA93197.1 - 3.1e-05 24.9 0.0 4.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AJA93197.1 - 4.8e-05 23.1 0.1 0.00086 19.0 0.0 2.1 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F UPF0020 PF01170.18 AJA93197.1 - 4.9e-05 23.1 0.1 0.0004 20.1 0.1 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 GCD14 PF08704.10 AJA93197.1 - 0.00015 21.6 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 AJA93197.1 - 0.00018 21.6 0.0 0.0019 18.3 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.16 AJA93197.1 - 0.00023 21.0 0.0 0.00027 20.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_32 PF13679.6 AJA93197.1 - 0.00047 20.2 0.0 0.00059 19.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 AJA93197.1 - 0.00049 19.6 0.0 0.00071 19.1 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa N6_N4_Mtase PF01555.18 AJA93197.1 - 0.0014 18.4 0.2 0.0025 17.5 0.0 1.5 2 0 0 2 2 2 1 DNA methylase Methyltransf_5 PF01795.19 AJA93197.1 - 0.0014 18.2 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 MraW methylase family GidB PF02527.15 AJA93197.1 - 0.002 17.5 0.1 0.0032 16.8 0.1 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G DOT1 PF08123.13 AJA93197.1 - 0.0025 17.4 0.2 0.0041 16.7 0.2 1.6 1 1 0 1 1 1 1 Histone methylation protein DOT1 Spermine_synth PF01564.17 AJA93197.1 - 0.0028 17.1 0.1 0.0042 16.5 0.1 1.4 1 1 0 1 1 1 1 Spermine/spermidine synthase domain NodS PF05401.11 AJA93197.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 AJA93197.1 - 0.016 15.0 0.2 0.027 14.2 0.2 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_9 PF08003.11 AJA93197.1 - 0.024 13.5 0.0 0.037 12.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) TRM PF02005.16 AJA93197.1 - 0.037 13.2 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase FmrO PF07091.11 AJA93197.1 - 0.04 13.5 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) RrnaAD PF00398.20 AJA93197.1 - 0.068 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase N6_Mtase PF02384.16 AJA93197.1 - 0.075 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase CheR PF01739.18 AJA93197.1 - 0.085 12.3 0.0 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain EIF_2_alpha PF07541.12 AJA93198.1 - 1.3e-15 57.5 2.1 1.7e-15 57.1 0.1 2.1 1 1 2 3 3 3 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 AJA93198.1 - 6e-14 52.1 0.6 1.2e-13 51.2 0.6 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.9 AJA93198.1 - 0.0058 17.2 0.9 0.029 15.0 0.2 2.3 1 1 1 2 2 2 1 Exosome component EXOSC1/CSL4 S1_2 PF13509.6 AJA93198.1 - 0.014 15.5 0.1 0.07 13.2 0.0 2.3 2 0 0 2 2 2 0 S1 domain COG5 PF10392.9 AJA93198.1 - 0.5 10.6 4.8 0.24 11.5 1.2 2.1 2 1 0 2 2 2 0 Golgi transport complex subunit 5 PEPCK_ATP PF01293.20 AJA93200.1 - 1.6e-218 726.1 0.0 1.8e-218 725.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Glycos_transf_1 PF00534.20 AJA93201.1 - 2.1e-37 128.3 0.0 4.6e-37 127.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AJA93201.1 - 5.8e-22 78.6 0.0 1.1e-21 77.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AJA93201.1 - 9.7e-14 51.7 0.0 3.2e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AJA93201.1 - 2.8e-07 30.8 0.0 1e-06 29.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AJA93201.1 - 6.9e-07 29.4 1.0 1.9e-06 28.0 0.4 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_4_4 PF13579.6 AJA93201.1 - 0.0077 16.7 0.0 0.014 15.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain eIF-5_eIF-2B PF01873.17 AJA93202.1 - 8.2e-30 103.1 0.0 1e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.6 AJA93202.1 - 0.002 18.5 0.8 0.0027 18.0 0.8 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 AJA93202.1 - 0.0039 16.7 1.3 0.0072 15.8 1.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Elf1 PF05129.13 AJA93202.1 - 0.0068 16.4 0.4 0.011 15.7 0.4 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-TFIIB PF13453.6 AJA93202.1 - 0.18 11.2 2.5 0.3 10.5 2.5 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.6 AJA93202.1 - 0.21 11.6 2.4 30 4.6 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DUF1512 PF07431.12 AJA93203.1 - 3.3e-121 404.6 3.2 3.7e-121 404.5 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1512) ANAPC2 PF08672.11 AJA93203.1 - 0.12 12.8 0.5 0.37 11.3 0.1 1.9 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 TPR_2 PF07719.17 AJA93204.1 - 3.6e-19 67.2 0.0 3.7e-05 23.5 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 AJA93204.1 - 7.8e-16 57.2 0.7 0.0043 16.8 0.2 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 AJA93204.1 - 7.1e-11 42.6 0.0 6e-06 26.8 0.0 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 AJA93204.1 - 7.6e-11 41.3 1.6 0.0042 17.2 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 AJA93204.1 - 1.1e-10 41.0 0.1 0.083 12.6 0.0 4.3 2 1 2 4 4 4 3 TPR repeat TPR_17 PF13431.6 AJA93204.1 - 2.3e-10 40.1 0.7 0.0008 19.6 0.0 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 AJA93204.1 - 4.7e-10 39.8 0.1 5.5e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AJA93204.1 - 3.7e-09 36.6 0.1 0.0052 17.5 0.0 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 AJA93204.1 - 7.9e-07 29.3 0.3 0.0056 17.2 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 AJA93204.1 - 8.1e-06 26.0 0.0 0.11 12.8 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 AJA93204.1 - 1.6e-05 25.0 0.0 0.011 15.9 0.0 2.7 2 1 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AJA93204.1 - 3.4e-05 24.0 0.1 5.6e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 AJA93204.1 - 0.00076 19.5 0.0 0.22 11.6 0.0 3.2 1 1 2 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 AJA93204.1 - 0.025 14.9 0.2 4.1 7.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 AJA93204.1 - 0.034 14.2 0.1 51 4.2 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat YfiO PF13525.6 AJA93204.1 - 0.14 11.9 0.6 1.9 8.2 0.0 2.5 2 1 1 3 3 3 0 Outer membrane lipoprotein PcrB PF01884.17 AJA93205.1 - 1.2e-53 181.9 0.1 1.5e-53 181.5 0.1 1.0 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.21 AJA93205.1 - 2.4e-09 37.0 0.2 1.7e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein IMPDH PF00478.25 AJA93205.1 - 9e-06 24.9 0.5 3e-05 23.2 0.5 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DpaA_N PF16924.5 AJA93205.1 - 0.0005 20.1 0.3 0.011 15.9 0.1 2.2 2 0 0 2 2 2 1 Dipicolinate synthase subunit A N-terminal domain Dus PF01207.17 AJA93205.1 - 0.00071 18.8 0.0 0.48 9.5 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) ThiG PF05690.14 AJA93205.1 - 0.0077 15.6 1.0 0.27 10.5 0.1 2.1 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Trp_syntA PF00290.20 AJA93205.1 - 0.0077 15.1 0.2 0.065 12.1 0.1 2.0 2 0 0 2 2 2 1 Tryptophan synthase alpha chain IGPS PF00218.21 AJA93205.1 - 0.0083 15.3 0.2 0.089 12.0 0.0 2.3 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.17 AJA93205.1 - 0.01 15.1 0.1 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase NanE PF04131.14 AJA93205.1 - 0.027 13.7 1.9 1.3 8.1 0.0 2.7 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 AJA93205.1 - 0.076 12.4 3.6 3.8 6.8 0.3 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase G3P_antiterm PF04309.12 AJA93205.1 - 0.15 11.4 0.9 0.67 9.3 0.1 2.2 2 1 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PepSY PF03413.19 AJA93208.1 - 3.6e-07 30.6 0.0 9.1e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain DUF3106 PF11304.8 AJA93208.1 - 0.00048 20.5 9.5 0.00093 19.6 9.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3106) DHR10 PF18595.1 AJA93209.1 - 0.0027 17.8 6.4 0.0027 17.8 6.4 3.1 3 1 0 3 3 2 1 Designed helical repeat protein 10 domain Mod_r PF07200.13 AJA93209.1 - 0.036 14.2 19.5 0.18 11.9 8.5 2.8 3 0 0 3 3 2 0 Modifier of rudimentary (Mod(r)) protein SLX9 PF15341.6 AJA93209.1 - 0.047 14.1 8.7 1.6 9.2 1.8 2.5 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 DUF1664 PF07889.12 AJA93209.1 - 0.076 13.1 19.3 0.18 11.9 1.6 4.5 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) Uds1 PF15456.6 AJA93209.1 - 0.1 12.8 0.2 0.1 12.8 0.2 2.5 2 0 0 2 2 2 0 Up-regulated During Septation Bacillus_HBL PF05791.11 AJA93209.1 - 0.13 12.0 10.9 0.12 12.2 3.1 2.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FlgM PF04316.13 AJA93209.1 - 0.19 12.1 1.0 38 4.7 0.0 3.4 4 0 0 4 4 2 0 Anti-sigma-28 factor, FlgM Med15_fungi PF05397.12 AJA93209.1 - 0.23 11.8 2.2 2.3 8.5 0.1 3.3 2 1 1 3 3 3 0 Mediator complex subunit 15 EzrA PF06160.12 AJA93209.1 - 0.39 8.8 23.9 1.1 7.3 4.7 2.4 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA ADIP PF11559.8 AJA93209.1 - 0.55 10.3 16.6 1.9 8.5 7.0 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding SAM_KSR1 PF13543.6 AJA93209.1 - 0.67 10.1 5.6 13 5.9 0.1 2.6 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 DUF438 PF04282.13 AJA93209.1 - 0.69 9.9 7.5 0.36 10.8 0.5 3.9 3 0 0 3 3 3 0 Family of unknown function (DUF438) Exonuc_VII_L PF02601.15 AJA93209.1 - 1.2 8.7 11.7 1.3 8.5 4.2 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit Fez1 PF06818.15 AJA93209.1 - 1.5 9.3 20.0 1.5 9.2 8.1 3.0 2 1 1 3 3 3 0 Fez1 Arc_PepC_II PF06847.11 AJA93209.1 - 1.6 9.3 6.0 1.6 9.3 0.4 3.2 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II STAT_alpha PF01017.20 AJA93209.1 - 1.9 8.4 13.7 1.1 9.2 1.8 3.2 2 1 0 2 2 2 0 STAT protein, all-alpha domain SesA PF17107.5 AJA93209.1 - 1.9 8.7 10.2 1.2 9.3 2.4 3.4 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DivIC PF04977.15 AJA93209.1 - 3.4 7.5 5.7 2.2 8.1 1.7 2.9 2 0 0 2 2 2 0 Septum formation initiator DASH_Dam1 PF08653.10 AJA93209.1 - 4.1 7.3 8.3 0.52 10.2 0.9 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 TMPIT PF07851.13 AJA93209.1 - 4.1 6.6 17.0 4.6 6.4 2.5 2.8 2 1 0 2 2 2 0 TMPIT-like protein DUF2203 PF09969.9 AJA93209.1 - 4.8 7.9 12.4 6.7 7.4 2.9 3.3 2 1 1 4 4 3 0 Uncharacterized conserved protein (DUF2203) DUF489 PF04356.12 AJA93209.1 - 4.9 7.1 5.7 5.6 6.9 0.9 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF489) YtxH PF12732.7 AJA93209.1 - 5.5 7.6 8.4 2.5 8.7 1.3 3.5 2 2 0 2 2 2 0 YtxH-like protein DUF641 PF04859.12 AJA93209.1 - 6.4 7.1 13.7 1.5 9.1 3.5 3.4 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) FliD_N PF02465.18 AJA93209.1 - 6.5 7.5 14.2 1.4e+04 -3.2 13.5 3.5 1 1 0 1 1 0 0 Flagellar hook-associated protein 2 N-terminus YozE_SAM_like PF06855.12 AJA93211.1 - 0.4 10.9 3.5 0.46 10.7 0.1 2.8 3 0 0 3 3 3 0 YozE SAM-like fold YpjP PF14005.6 AJA93211.1 - 3.3 7.8 5.9 27 4.8 0.1 3.7 3 2 0 3 3 3 0 YpjP-like protein GATase_6 PF13522.6 AJA93212.1 - 6.7e-12 45.8 0.0 1.3e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AJA93212.1 - 8.1e-12 45.1 0.0 1.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 AJA93212.1 - 8.7e-08 31.8 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 AJA93212.1 - 0.0004 19.4 0.0 0.00082 18.4 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 AJA93212.1 - 0.0094 14.7 0.0 0.054 12.2 0.0 2.2 3 0 0 3 3 3 1 Glutamine amidotransferases class-II Ribosomal_L40e PF01020.17 AJA93213.1 - 9.5e-07 28.6 5.9 1.1e-06 28.4 5.9 1.1 1 0 0 1 1 1 1 Ribosomal L40e family DZR PF12773.7 AJA93213.1 - 0.0012 18.9 0.6 0.0013 18.7 0.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 AJA93213.1 - 0.0032 17.1 0.1 0.0048 16.6 0.1 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-AD PF07776.15 AJA93213.1 - 0.0032 17.7 1.2 0.0035 17.5 1.2 1.1 1 0 0 1 1 1 1 Zinc-finger associated domain (zf-AD) zinc_ribbon_15 PF17032.5 AJA93213.1 - 0.014 16.2 0.3 0.015 16.0 0.3 1.1 1 0 0 1 1 1 0 zinc-ribbon family HypA PF01155.19 AJA93213.1 - 0.02 14.9 0.4 0.021 14.9 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_3 PF13920.6 AJA93213.1 - 0.04 13.8 2.5 0.046 13.6 2.5 1.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 AJA93213.1 - 0.072 12.5 0.7 0.1 12.0 0.7 1.3 1 0 0 1 1 1 0 zinc-ribbon domain CTV_P23 PF04808.12 AJA93213.1 - 0.13 11.8 0.5 0.13 11.8 0.5 1.0 1 0 0 1 1 1 0 Citrus tristeza virus (CTV) P23 protein zf-trcl PF13451.6 AJA93213.1 - 9.5 6.2 8.3 1.2 9.1 2.8 2.0 1 1 1 2 2 2 0 Probable zinc-ribbon domain Phos_pyr_kin PF08543.12 AJA93214.1 - 2.4e-72 243.3 3.6 3.9e-72 242.6 3.6 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ThiP_synth PF10120.9 AJA93214.1 - 1.2e-50 171.3 0.0 2.3e-50 170.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine-phosphate synthase PfkB PF00294.24 AJA93214.1 - 4.9e-07 29.4 0.0 8.5e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 AJA93214.1 - 5.2e-06 26.1 0.4 1e-05 25.2 0.4 1.5 1 0 0 1 1 1 1 Carbohydrate kinase Goodbye PF17109.5 AJA93214.1 - 0.047 14.1 0.1 0.14 12.6 0.1 1.8 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain GerE PF00196.19 AJA93214.1 - 0.065 12.8 0.3 0.2 11.2 0.3 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF973 PF06157.11 AJA93216.1 - 0.014 14.5 7.4 0.016 14.3 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) RDD PF06271.12 AJA93216.1 - 0.04 14.1 2.0 0.046 13.9 2.0 1.0 1 0 0 1 1 1 0 RDD family DUF3149 PF11346.8 AJA93216.1 - 0.075 12.7 2.3 0.075 12.7 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3149) YndJ PF14158.6 AJA93216.1 - 0.2 11.0 0.9 0.34 10.2 0.5 1.6 1 1 1 2 2 2 0 YndJ-like protein Pox_A14 PF05767.12 AJA93216.1 - 0.31 11.2 2.9 0.51 10.5 2.9 1.3 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF3185 PF11381.8 AJA93216.1 - 0.47 10.5 7.7 4.6 7.3 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Neurensin PF14927.6 AJA93216.1 - 1.4 8.7 4.8 2.9 7.6 4.8 1.8 1 1 0 1 1 1 0 Neurensin UL41A PF17591.2 AJA93216.1 - 1.6 8.9 3.9 1.1 9.5 0.3 2.0 2 0 0 2 2 2 0 Herpesvirus UL41A DUF2371 PF10177.9 AJA93216.1 - 5.2 7.3 5.7 0.8 9.9 0.8 1.8 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) HIGH_NTase1_ass PF16581.5 AJA93217.1 - 0.0024 17.9 2.2 0.0024 17.9 2.2 1.5 1 1 0 1 1 1 1 Cytidyltransferase-related C-terminal region Leptin PF02024.15 AJA93217.1 - 0.0026 17.5 2.4 0.0045 16.8 2.4 1.3 1 0 0 1 1 1 1 Leptin YqgF PF14639.6 AJA93217.1 - 0.023 14.5 2.4 0.52 10.1 0.5 2.2 1 1 1 2 2 2 0 Holliday-junction resolvase-like of SPT6 DUF3161 PF11362.8 AJA93217.1 - 0.036 14.0 0.3 0.077 13.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) DSPn PF14671.6 AJA93217.1 - 0.039 14.4 0.1 0.051 14.0 0.1 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half FeoB_Cyto PF17910.1 AJA93217.1 - 1.8 9.2 6.4 1.1 9.8 1.2 2.6 1 1 1 2 2 2 0 FeoB cytosolic helical domain NUDIX PF00293.28 AJA93218.1 - 2.1e-18 66.6 0.0 3.2e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain UbiA PF01040.18 AJA93219.1 - 1.8e-36 125.7 21.0 2.4e-36 125.3 21.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family ATP1G1_PLM_MAT8 PF02038.16 AJA93219.1 - 0.13 11.7 1.4 18 4.9 0.0 3.3 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family DUF2070 PF09843.9 AJA93219.1 - 6.6 4.9 11.5 5.1 5.3 10.1 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) MIP PF00230.20 AJA93220.1 - 3.1e-51 174.3 17.4 3.6e-51 174.0 17.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein FtsX PF02687.21 AJA93221.1 - 5.3e-18 65.3 2.3 1.9e-17 63.5 0.7 2.3 2 0 0 2 2 2 1 FtsX-like permease family MacB_PCD PF12704.7 AJA93221.1 - 8.1e-15 55.7 1.0 1.3e-14 55.0 1.0 1.3 1 0 0 1 1 1 1 MacB-like periplasmic core domain DUF4064 PF13273.6 AJA93221.1 - 0.26 11.6 12.0 5.6 7.3 8.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) AdoHcyase PF05221.17 AJA93222.1 - 7.2e-59 199.4 0.0 5.2e-30 104.6 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AJA93222.1 - 2.1e-50 170.9 0.3 2.1e-50 170.9 0.3 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 AJA93222.1 - 1.6e-07 30.9 0.1 4.6e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AJA93222.1 - 6.9e-06 25.7 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 AJA93222.1 - 0.00092 19.5 0.3 0.0034 17.6 0.1 2.1 3 0 0 3 3 3 1 TrkA-N domain AlaDh_PNT_C PF01262.21 AJA93222.1 - 0.077 12.3 8.9 0.093 12.0 3.3 3.0 3 1 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AJA93222.1 - 0.13 12.1 0.6 0.39 10.6 0.6 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Guanylate_cyc_2 PF09778.9 AJA93223.1 - 0.067 12.5 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Guanylylate cyclase MaoC_dehydratas PF01575.19 AJA93223.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain PvlArgDC PF01862.16 AJA93224.1 - 4.4e-57 192.4 0.0 5e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) GSDH PF07995.11 AJA93225.1 - 6.9e-77 259.0 0.0 9.4e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 AJA93225.1 - 0.015 15.5 0.1 9.1 6.9 0.0 3.1 2 0 0 2 2 2 0 Two component regulator propeller DUF5122 PF17164.4 AJA93225.1 - 0.1 12.9 0.7 0.51 10.7 0.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller Med30 PF11315.8 AJA93226.1 - 0.00036 20.8 1.2 0.00041 20.6 1.2 1.2 1 0 0 1 1 1 1 Mediator complex subunit 30 Glyco_hydro_99 PF16317.5 AJA93226.1 - 0.0055 15.9 0.2 0.0055 15.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Prominin PF05478.11 AJA93226.1 - 0.011 13.8 0.4 0.012 13.6 0.4 1.0 1 0 0 1 1 1 0 Prominin ALIX_LYPXL_bnd PF13949.6 AJA93226.1 - 0.017 14.5 2.4 0.02 14.2 2.4 1.0 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Fib_alpha PF08702.10 AJA93226.1 - 0.044 14.0 2.3 0.05 13.8 1.8 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FapA PF03961.13 AJA93226.1 - 0.26 9.9 3.8 0.27 9.8 3.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Med15 PF09606.10 AJA93229.1 - 0.026 13.2 1.9 0.033 12.9 1.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2613 PF11021.8 AJA93229.1 - 0.11 12.6 0.4 0.33 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF2407_C PF13373.6 AJA93229.1 - 0.16 12.1 0.4 0.29 11.3 0.4 1.5 1 1 0 1 1 1 0 DUF2407 C-terminal domain RNA_pol_Rpc4 PF05132.14 AJA93229.1 - 0.28 11.6 2.1 0.38 11.2 2.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 ABC_tran PF00005.27 AJA93231.1 - 2.6e-29 102.5 0.0 6.1e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AJA93231.1 - 3.3e-11 43.6 1.4 2.7e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 AJA93231.1 - 1.3e-06 29.0 0.7 4.6e-06 27.3 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 AJA93231.1 - 1.2e-05 25.3 0.5 0.0098 15.6 0.4 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AJA93231.1 - 8.4e-05 23.2 0.1 0.00014 22.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AJA93231.1 - 0.00035 20.2 0.2 0.00072 19.2 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.7 AJA93231.1 - 0.012 14.5 0.7 0.065 12.1 0.1 1.9 1 1 0 2 2 2 0 AAA-like domain MeaB PF03308.16 AJA93231.1 - 0.017 14.1 0.1 0.031 13.2 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 AJA93231.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.21 AJA93231.1 - 0.034 13.5 0.1 0.072 12.5 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 AJA93231.1 - 0.043 13.3 1.5 2.7 7.4 0.1 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AJA93231.1 - 0.057 13.7 0.3 0.29 11.4 0.2 2.2 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AJA93231.1 - 0.075 12.9 0.3 0.17 11.8 0.3 1.6 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 AJA93231.1 - 0.095 12.9 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 AJA93231.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaJ PF00226.31 AJA93232.1 - 4.4e-09 36.3 0.0 9.1e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain HTH_45 PF14947.6 AJA93233.1 - 3.9e-16 58.8 0.2 4.5e-16 58.6 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix Rrf2 PF02082.20 AJA93233.1 - 0.00029 21.1 0.1 0.00041 20.6 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator RNA_pol_Rpc34 PF05158.12 AJA93233.1 - 0.00061 19.3 0.0 0.00074 19.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Mrr_N PF14338.6 AJA93233.1 - 0.0016 18.5 0.1 0.0021 18.1 0.1 1.3 1 0 0 1 1 1 1 Mrr N-terminal domain DUF4364 PF14277.6 AJA93233.1 - 0.0027 17.5 0.1 0.0032 17.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_34 PF13601.6 AJA93233.1 - 0.0069 16.5 0.2 0.01 16.0 0.2 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF505 PF04458.12 AJA93233.1 - 0.033 12.6 0.1 0.033 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) HTH_27 PF13463.6 AJA93233.1 - 0.043 14.3 0.1 0.059 13.9 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain RPA_C PF08784.11 AJA93233.1 - 0.046 14.4 0.0 0.062 14.0 0.0 1.1 1 0 0 1 1 1 0 Replication protein A C terminal Mannosyl_trans2 PF04188.13 AJA93233.1 - 0.082 12.2 0.0 0.085 12.1 0.0 1.0 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) TrmB PF01978.19 AJA93233.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Ferritin PF00210.24 AJA93234.1 - 3.9e-20 72.2 0.0 5.6e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain FAA_hydrolase PF01557.18 AJA93235.1 - 1.7e-69 233.8 0.0 2.1e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 AJA93235.1 - 0.042 14.7 0.0 0.12 13.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) JmjN PF02375.17 AJA93236.1 - 0.038 14.0 2.3 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 jmjN domain HYR PF02494.16 AJA93237.1 - 9.7e-59 195.7 64.5 1e-06 29.0 1.8 12.6 12 0 0 12 12 12 11 HYR domain NHL PF01436.21 AJA93237.1 - 9.9e-30 101.1 6.1 6.3e-05 22.8 0.2 6.9 6 0 0 6 6 6 6 NHL repeat HemolysinCabind PF00353.19 AJA93237.1 - 3e-12 46.3 44.1 5.5e-07 29.4 16.4 4.2 2 1 2 4 4 4 3 RTX calcium-binding nonapeptide repeat (4 copies) DUF5011 PF16403.5 AJA93237.1 - 9.1e-12 44.9 6.7 3.4 7.9 0.3 9.3 10 0 0 10 10 10 4 Domain of unknown function (DUF5011) Big_3_4 PF13754.6 AJA93237.1 - 1.6e-11 43.9 0.5 3.9 7.3 0.1 9.0 8 1 3 11 11 11 3 Domain of unknown function DUF5128 PF17170.4 AJA93237.1 - 2.7e-11 43.2 14.3 3.5e-07 29.7 2.4 3.2 3 0 0 3 3 3 2 6-bladed beta-propeller SGL PF08450.12 AJA93237.1 - 3.4e-07 30.1 0.3 0.032 13.8 0.0 4.3 3 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region REJ PF02010.15 AJA93237.1 - 3.8e-07 29.3 28.4 0.38 9.5 0.1 7.3 5 2 1 8 8 8 6 REJ domain TolB_like PF15869.5 AJA93237.1 - 8.5e-07 28.5 0.9 0.00039 19.8 0.1 2.5 2 1 0 2 2 2 2 TolB-like 6-blade propeller-like ChitinaseA_N PF08329.10 AJA93237.1 - 0.0048 16.6 16.1 17 5.1 0.3 7.5 7 1 1 8 8 8 0 Chitinase A, N-terminal domain Phytase-like PF13449.6 AJA93237.1 - 0.037 14.0 1.6 6.6 6.6 0.1 4.1 3 2 0 5 5 5 0 Esterase-like activity of phytase SBBP PF06739.11 AJA93237.1 - 0.53 10.3 0.0 0.53 10.3 0.0 8.1 12 0 0 12 12 12 0 Beta-propeller repeat Big_3_3 PF13750.6 AJA93237.1 - 3.3 7.4 56.8 0.38 10.4 0.6 10.4 6 4 4 12 12 12 0 Bacterial Ig-like domain (group 3) Peripla_BP_2 PF01497.18 AJA93238.1 - 5.5e-23 81.8 0.0 7.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Fis1_TPR_N PF14852.6 AJA93238.1 - 0.046 13.4 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat V-ATPase_H_C PF11698.8 AJA93238.1 - 0.14 12.3 0.1 0.46 10.6 0.1 2.0 1 0 0 1 1 1 0 V-ATPase subunit H Mis14 PF08641.12 AJA93238.1 - 0.18 12.1 0.9 0.39 11.0 0.1 1.9 2 0 0 2 2 2 0 Kinetochore protein Mis14 like eIF-1a PF01176.19 AJA93239.1 - 4.7e-19 67.9 1.5 6.3e-19 67.5 1.5 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myosin_N PF02736.19 AJA93239.1 - 0.098 12.5 1.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain MCM6_C PF18263.1 AJA93239.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain QueC PF06508.13 AJA93240.1 - 6.7e-51 172.8 0.1 7.7e-51 172.6 0.1 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AJA93240.1 - 2.1e-06 27.6 0.0 3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.19 AJA93240.1 - 0.0016 17.8 0.1 0.0021 17.4 0.1 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase ThiI PF02568.14 AJA93240.1 - 0.0039 16.8 0.1 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 AJA93240.1 - 0.019 14.1 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 NAD synthase DUF1737 PF08410.10 AJA93240.1 - 0.06 13.2 0.1 3.2 7.7 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1737) ATP_bind_3 PF01171.20 AJA93240.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 PP-loop family PAC2 PF09754.9 AJA93241.1 - 5.1e-28 98.6 0.0 5.8e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 PAC2 family tRNA-synt_1b PF00579.25 AJA93242.1 - 3.8e-42 144.6 0.0 5.2e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Complex1_49kDa PF00346.19 AJA93243.1 - 1.4e-74 250.6 0.0 2.9e-58 197.1 0.0 2.1 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit BPD_transp_1 PF00528.22 AJA93244.1 - 3.9e-23 82.1 15.5 3.9e-23 82.1 15.5 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component bact-PGI_C PF10432.9 AJA93245.1 - 5.8e-34 117.3 0.0 9.7e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal SIS domain SIS PF01380.22 AJA93245.1 - 1.7e-06 27.9 0.3 3.2e-06 27.0 0.1 1.6 2 0 0 2 2 2 1 SIS domain ECH_2 PF16113.5 AJA93245.1 - 0.14 11.7 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase GSDH PF07995.11 AJA93247.1 - 1.7e-83 280.7 0.1 2.1e-83 280.4 0.1 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase DUF5122 PF17164.4 AJA93247.1 - 0.034 14.5 0.1 3.2 8.1 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller S-AdoMet_synt_C PF02773.16 AJA93248.1 - 3.1e-71 237.8 0.2 5.8e-71 236.9 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 AJA93248.1 - 5.5e-47 158.9 0.0 2.2e-46 157.0 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 AJA93248.1 - 9.5e-41 138.5 0.9 3.1e-40 136.8 0.1 2.2 2 1 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 AJA93248.1 - 0.15 10.9 1.1 0.98 8.1 0.2 2.3 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) tRNA-synt_1c PF00749.21 AJA93249.1 - 1.4e-75 254.1 0.0 2.2e-75 253.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 AJA93249.1 - 7.5e-27 94.3 0.7 6.8e-26 91.2 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain HU-CCDC81_bac_2 PF18175.1 AJA93249.1 - 0.12 12.3 10.1 4.3 7.3 0.2 4.2 4 0 0 4 4 4 0 CCDC81-like prokaryotic HU domain 2 PP2C_C PF07830.13 AJA93249.1 - 5.7 7.5 7.9 41 4.7 2.3 3.4 3 1 1 4 4 4 0 Protein serine/threonine phosphatase 2C, C-terminal domain SRC-1 PF08832.10 AJA93251.1 - 0.11 13.5 0.9 1.4 10.0 0.2 2.3 2 0 0 2 2 2 0 Steroid receptor coactivator PALP PF00291.25 AJA93252.1 - 3.7e-47 161.1 1.0 4.4e-47 160.9 1.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1610 PF07754.11 AJA93253.1 - 0.00012 22.0 4.6 0.00012 22.0 4.6 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1610) C1_2 PF03107.16 AJA93253.1 - 0.00049 20.3 8.0 0.06 13.7 0.2 2.1 1 1 1 2 2 2 2 C1 domain zf-CHY PF05495.12 AJA93253.1 - 0.00089 19.7 3.9 0.0012 19.3 3.9 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-B_box PF00643.24 AJA93253.1 - 0.57 10.4 9.7 3.2 8.0 5.5 2.8 2 1 0 2 2 2 0 B-box zinc finger zinc_ribbon_10 PF10058.9 AJA93253.1 - 1.8 8.3 15.7 53 3.6 0.3 3.7 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein ZZ PF00569.17 AJA93253.1 - 3 7.8 9.9 4 7.3 0.6 3.0 2 1 1 3 3 3 0 Zinc finger, ZZ type zf-AN1 PF01428.16 AJA93253.1 - 4.4 7.6 11.2 6.1 7.1 2.5 2.5 2 1 0 2 2 2 0 AN1-like Zinc finger Gin PF10764.9 AJA93253.1 - 6.7 6.8 8.9 1.7 8.6 0.1 3.0 2 2 1 3 3 3 0 Inhibitor of sigma-G Gin Nudix_N_2 PF14803.6 AJA93253.1 - 9.5 6.2 12.8 1.1 9.2 2.0 3.4 3 1 0 3 3 3 0 Nudix N-terminal Ribosomal_L21e PF01157.18 AJA93254.1 - 3.4e-19 68.6 1.9 4.4e-19 68.2 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L21e AP_endonuc_2 PF01261.24 AJA93255.1 - 4.7e-35 120.9 0.0 1.1e-34 119.7 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF5537 PF17690.1 AJA93255.1 - 0.016 14.9 0.2 0.18 11.5 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5537) ACC_central PF08326.12 AJA93255.1 - 0.018 13.3 0.0 0.026 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region Ala_racemase_N PF01168.20 AJA93255.1 - 0.14 11.8 0.0 1.6 8.3 0.0 2.0 1 1 1 2 2 2 0 Alanine racemase, N-terminal domain ASCH PF04266.14 AJA93256.1 - 1.2e-12 48.4 0.1 1.8e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 ASCH domain Phage_integr_3 PF16795.5 AJA93256.1 - 0.087 12.7 1.2 0.25 11.3 0.7 2.0 1 1 1 2 2 2 0 Archaeal phage integrase Nitr_red_bet_C PF14711.6 AJA93256.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal zinc_ribbon_4 PF13717.6 AJA93257.1 - 0.0049 16.7 4.4 0.058 13.3 4.4 2.1 1 1 0 1 1 1 1 zinc-ribbon domain Lar_restr_allev PF14354.6 AJA93257.1 - 0.022 15.1 2.0 0.048 14.0 2.0 1.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar DZR PF12773.7 AJA93257.1 - 0.05 13.6 0.9 0.073 13.1 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 AJA93257.1 - 0.063 13.3 0.4 0.075 13.1 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S27e PF01667.17 AJA93257.1 - 0.066 12.9 3.4 0.2 11.4 3.4 1.7 1 1 0 1 1 1 0 Ribosomal protein S27 zinc_ribbon_6 PF14599.6 AJA93257.1 - 0.098 12.7 0.7 0.14 12.2 0.7 1.2 1 0 0 1 1 1 0 Zinc-ribbon CpXC PF14353.6 AJA93257.1 - 0.13 12.3 1.6 2.8 8.0 0.2 2.0 1 1 1 2 2 2 0 CpXC protein zf-Mss51 PF13824.6 AJA93257.1 - 0.16 12.1 1.8 0.23 11.6 1.8 1.4 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.6 AJA93257.1 - 0.24 10.9 5.2 8.8 5.9 5.2 2.2 1 1 0 1 1 1 0 zinc-ribbon domain TFIIS_C PF01096.18 AJA93257.1 - 0.31 10.9 3.3 9 6.2 0.7 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Sgf11 PF08209.11 AJA93257.1 - 0.51 9.9 4.3 3.2 7.4 0.5 2.5 2 1 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF983 PF06170.12 AJA93257.1 - 2 8.9 3.0 20 5.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF983) zf-C2H2_3 PF13878.6 AJA93257.1 - 9.8 6.1 6.8 3.2 7.7 0.9 2.3 2 1 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C2H2 PF00096.26 AJA93258.1 - 0.0078 16.6 0.6 0.014 15.9 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 AJA93258.1 - 0.01 16.6 0.8 0.018 15.8 0.6 1.5 2 0 0 2 2 2 0 C2H2-type zinc finger Tnp_zf-ribbon_2 PF13842.6 AJA93258.1 - 0.016 16.0 0.9 0.026 15.3 0.9 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-C2H2_2 PF12756.7 AJA93258.1 - 0.017 15.4 0.5 0.019 15.3 0.5 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 AJA93258.1 - 0.049 12.8 0.4 0.053 12.7 0.4 1.0 1 0 0 1 1 1 0 Putative actin-like family zf-BED PF02892.15 AJA93258.1 - 0.063 13.3 2.3 0.11 12.5 2.3 1.5 1 1 0 1 1 1 0 BED zinc finger Thioredoxin_4 PF13462.6 AJA93259.1 - 7.7e-30 104.2 0.1 1.5e-29 103.3 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AJA93259.1 - 3.7e-15 56.2 2.2 9.1e-14 51.7 2.2 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJA93259.1 - 1.1e-06 29.1 0.1 2.5e-06 27.9 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 AJA93259.1 - 0.039 13.8 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein FAD_oxidored PF12831.7 AJA93260.1 - 5.2e-15 55.7 0.4 1.3e-14 54.5 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AJA93260.1 - 5.4e-15 55.5 0.1 2.5e-14 53.3 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 AJA93260.1 - 6.3e-14 52.3 1.3 4.1e-07 29.9 0.9 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AJA93260.1 - 1.1e-13 51.1 2.0 2.3e-08 33.5 0.4 2.1 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 AJA93260.1 - 1.6e-10 40.4 0.9 0.00015 20.7 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 AJA93260.1 - 3.3e-09 36.0 1.9 4.3e-08 32.3 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 AJA93260.1 - 1.7e-08 33.9 0.0 2.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 AJA93260.1 - 2.6e-08 33.4 1.5 6.5e-08 32.2 1.5 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AJA93260.1 - 2.5e-07 30.1 1.4 4e-07 29.5 0.3 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AJA93260.1 - 2.6e-05 24.4 0.2 5.2e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AJA93260.1 - 4.1e-05 24.0 1.1 0.0031 18.1 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 AJA93260.1 - 6.6e-05 22.4 0.4 0.0032 16.9 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Thi4 PF01946.17 AJA93260.1 - 0.00012 21.4 0.6 0.00036 19.8 0.1 1.9 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 AJA93260.1 - 0.00012 21.4 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 AJA93260.1 - 0.00047 19.5 1.0 0.00087 18.6 1.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AJA93260.1 - 0.0023 17.9 0.1 0.0042 17.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 AJA93260.1 - 0.0048 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 AJA93260.1 - 0.0083 16.6 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding XdhC_C PF13478.6 AJA93260.1 - 0.061 13.8 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain SMC_ScpB PF04079.16 AJA93261.1 - 1.2e-34 119.2 0.3 1.5e-34 118.9 0.3 1.1 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB HTH_20 PF12840.7 AJA93261.1 - 0.015 15.3 0.1 0.74 9.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF5013 PF16405.5 AJA93261.1 - 0.019 15.3 0.1 0.023 15.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5013) TBPIP PF07106.13 AJA93261.1 - 0.02 14.8 0.1 1.5 8.8 0.0 2.5 2 1 0 2 2 2 0 TBPIP/Hop2 winged helix domain Y_Y_Y PF07495.13 AJA93261.1 - 0.033 14.1 0.1 0.089 12.8 0.1 1.7 1 0 0 1 1 1 0 Y_Y_Y domain PadR PF03551.14 AJA93261.1 - 0.043 13.8 0.4 0.24 11.4 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DNase-RNase PF02577.14 AJA93261.1 - 0.096 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Bifunctional nuclease Acetyltransf_3 PF13302.7 AJA93262.1 - 2.7e-19 70.2 0.0 3.2e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AJA93262.1 - 1.3e-11 44.9 1.8 1.5e-11 44.7 1.8 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AJA93262.1 - 1.2e-10 41.7 0.1 1.4e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AJA93262.1 - 2.9e-06 27.0 0.0 1.3e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AJA93262.1 - 3.1e-05 23.9 0.2 4e-05 23.5 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AJA93262.1 - 0.0035 17.7 0.3 0.0054 17.1 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain YmdB PF13277.6 AJA93262.1 - 0.056 12.8 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 YmdB-like protein Pox_polyA_pol_N PF12630.7 AJA93262.1 - 0.07 13.5 1.7 0.15 12.4 1.7 1.6 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain MtN3_slv PF03083.16 AJA93263.1 - 4.3e-11 42.7 3.4 5.1e-11 42.5 3.4 1.0 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 AJA93263.1 - 7.5e-06 25.6 0.4 7.5e-06 25.6 0.4 1.5 2 0 0 2 2 2 1 PQ loop repeat DUF996 PF06195.13 AJA93263.1 - 0.011 16.0 2.3 0.011 16.0 2.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF996) MASE3 PF17159.4 AJA93263.1 - 0.032 13.9 1.8 0.037 13.7 1.8 1.1 1 0 0 1 1 1 0 Membrane-associated sensor domain DUF1211 PF06736.11 AJA93263.1 - 0.042 14.3 2.4 0.6 10.6 3.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) DUF3784 PF12650.7 AJA93263.1 - 0.056 13.6 7.9 0.61 10.3 7.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) DUF2583 PF10762.9 AJA93263.1 - 1.2 9.6 5.5 0.29 11.6 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Candidatus_Nitrosopelagicus_brevis-ASM81218v1/GCA_000812185.1_ASM81218v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Candidatus_Nitrosopelagicus_brevis-ASM81218v1/GCA_000812185.1_ASM81218v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Candidatus_Nitrosopelagicus_brevis-ASM81218v1/GCA_000812185.1_ASM81218v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Candidatus_Nitrosopelagicus_brevis-ASM81218v1/GCA_000812185.1_ASM81218v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 16:13:20 2019 # [ok]