# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- S4 PF01479.25 EAN30387.1 - 6.6e-07 28.9 0.0 1.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_L4 PF00573.22 EAN30388.1 - 0.0011 18.7 0.6 0.0018 18.0 0.4 1.4 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L2_C PF03947.18 EAN30389.1 - 1.2e-32 112.8 0.0 3.1e-32 111.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EAN30389.1 - 1.2e-05 25.2 1.0 1.2e-05 25.2 1.0 2.1 2 1 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Rpr2 PF04032.16 EAN30389.1 - 0.058 13.7 0.1 0.088 13.1 0.1 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_S19 PF00203.21 EAN30390.1 - 1.5e-05 24.8 0.1 1.7e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_S3_C PF00189.20 EAN30391.1 - 4.6e-17 62.3 0.1 7e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain Ribosomal_L16 PF00252.18 EAN30392.1 - 6.1e-28 97.5 0.7 7e-28 97.3 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L14 PF00238.19 EAN30394.1 - 1.2e-07 31.8 4.8 1.4e-07 31.6 4.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF1265 PF06887.14 EAN30396.1 - 0.063 13.2 2.9 3.8 7.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) Ribosomal_L5_C PF00673.21 EAN30396.1 - 0.072 13.3 0.1 0.11 12.7 0.1 1.4 1 1 0 1 1 1 0 ribosomal L5P family C-terminus Ribosomal_S8 PF00410.19 EAN30397.1 - 2.2e-09 37.3 0.4 2.7e-09 37.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S5 PF00333.20 EAN30399.1 - 1.1e-08 34.9 0.1 1.9e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_L36 PF00444.18 EAN30401.1 - 2.5e-10 40.4 12.4 2.8e-10 40.2 12.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosom_S12_S23 PF00164.25 EAN30403.1 - 7e-21 74.0 5.3 8.4e-21 73.7 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S7 PF00177.21 EAN30404.1 - 0.019 14.6 0.6 0.035 13.8 0.4 1.8 1 1 0 1 1 1 0 Ribosomal protein S7p/S5e GTP_EFTU PF00009.27 EAN30405.1 - 1.6e-51 174.6 1.9 2.7e-51 173.9 1.9 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EAN30405.1 - 1.5e-23 83.3 0.0 2.9e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EAN30405.1 - 2.8e-14 53.2 2.5 8.6e-14 51.7 2.5 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAN30405.1 - 1.8e-05 24.8 0.2 4.9e-05 23.4 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAN30405.1 - 0.0015 18.5 0.9 0.008 16.1 0.0 2.1 1 1 0 2 2 2 1 RsgA GTPase Ribosomal_L23 PF00276.20 EAN30406.1 - 0.075 13.4 0.3 0.15 12.4 0.3 1.6 1 1 0 1 1 1 0 Ribosomal protein L23 Suv3_N PF18114.1 EAN30408.1 - 0.049 13.7 2.8 0.058 13.5 1.8 1.7 1 1 1 2 2 2 0 Suv3 helical N-terminal domain DUF4976 PF16347.5 EAN30408.1 - 0.21 11.8 3.0 0.58 10.4 2.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4976) AAA_2 PF07724.14 EAN30409.1 - 1.4e-32 113.2 0.0 2.5e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EAN30409.1 - 5.1e-09 36.7 0.2 2.3e-08 34.5 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAN30409.1 - 2.3e-07 30.6 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EAN30409.1 - 3.5e-07 30.3 0.0 8.3e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EAN30409.1 - 0.0015 18.1 0.9 0.0092 15.5 0.0 2.5 1 1 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 EAN30409.1 - 0.0047 16.1 0.0 0.013 14.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EAN30409.1 - 0.0078 16.8 0.2 0.0078 16.8 0.2 2.7 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EAN30409.1 - 0.012 15.4 0.1 0.034 13.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EAN30409.1 - 0.037 13.3 0.0 0.23 10.7 0.0 2.3 1 1 1 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 EAN30409.1 - 0.059 12.8 0.0 0.19 11.1 0.0 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EAN30409.1 - 0.084 13.2 0.2 0.35 11.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EAN30409.1 - 0.098 12.4 0.1 0.32 10.7 0.0 1.9 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EAN30409.1 - 0.13 12.8 0.1 0.57 10.7 0.1 2.0 1 1 0 1 1 1 0 ABC transporter tRNA_edit PF04073.15 EAN30409.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain T2SSE PF00437.20 EAN30409.1 - 0.17 10.9 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 EAN30409.1 - 0.26 11.0 0.5 0.92 9.2 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase RNA_helicase PF00910.22 EAN30409.1 - 0.6 10.5 0.0 0.6 10.5 0.0 3.9 4 1 0 4 4 3 0 RNA helicase AAA_2 PF07724.14 EAN30410.1 - 4.2e-36 124.6 0.1 1.4e-35 122.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EAN30410.1 - 7e-11 42.3 0.0 1.6e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EAN30410.1 - 4.4e-09 36.3 0.0 8.1e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 EAN30410.1 - 2e-08 34.7 0.1 1.1e-07 32.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EAN30410.1 - 0.0053 17.1 2.7 0.0079 16.6 0.6 2.6 2 1 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EAN30410.1 - 0.0094 16.5 0.1 0.042 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAN30410.1 - 0.017 15.4 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 EAN30410.1 - 0.032 14.4 0.6 0.085 13.0 0.0 2.1 2 0 0 2 2 2 0 Torsin DUF815 PF05673.13 EAN30410.1 - 0.034 13.3 0.1 8 5.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF815) T2SSE PF00437.20 EAN30410.1 - 0.05 12.6 0.1 3.3 6.7 0.0 2.2 1 1 1 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 EAN30410.1 - 0.077 12.4 0.0 0.81 9.0 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EAN30410.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 EAN30410.1 - 0.098 13.0 0.0 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 EAN30410.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EAN30410.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNase_T PF00929.24 EAN30411.1 - 0.19 12.3 1.4 0.19 12.3 1.4 1.1 1 0 0 1 1 1 0 Exonuclease RNA_pol_Rpb2_6 PF00562.28 EAN30414.1 - 1.3e-54 185.8 0.0 2.4e-54 184.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 EAN30414.1 - 4.6e-12 45.9 0.0 1.1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 EAN30414.1 - 9.1e-09 35.6 0.2 5e-07 30.0 0.2 2.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb1_2 PF00623.20 EAN30415.1 - 1.1e-21 77.8 0.0 8.7e-14 52.1 0.0 2.8 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EAN30415.1 - 1.3e-08 34.6 3.8 1.1e-05 25.0 3.8 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Actin_micro PF17003.5 EAN30416.1 - 0.00022 20.6 7.1 0.00022 20.5 6.8 1.2 1 1 0 1 1 1 1 Putative actin-like family Shisa PF13908.6 EAN30419.1 - 0.67 10.2 2.4 0.64 10.2 2.4 1.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Actin_micro PF17003.5 EAN30424.1 - 0.0012 18.1 5.7 0.0017 17.6 5.7 1.2 1 0 0 1 1 1 1 Putative actin-like family Orthopox_B11R PF07033.11 EAN30424.1 - 0.32 10.8 3.2 0.65 9.8 3.2 1.5 1 0 0 1 1 1 0 Orthopoxvirus B11R protein WD40_alt PF14077.6 EAN30424.1 - 0.53 10.2 4.5 0.43 10.5 0.9 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif RNA_pol_Rpb1_5 PF04998.17 EAN30428.1 - 5e-22 78.6 0.0 7.2e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 DUF4921 PF16268.5 EAN30429.1 - 0.0084 15.0 0.3 0.012 14.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4921) Ribosomal_S2 PF00318.20 EAN30430.1 - 1.5e-27 96.3 3.1 1.6e-27 96.1 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 Helicase_C_3 PF13625.6 EAN30430.1 - 0.061 13.5 0.0 0.093 12.9 0.0 1.2 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF1430 PF07242.11 EAN30431.1 - 0.056 13.7 0.5 0.056 13.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) YusW PF14039.6 EAN30431.1 - 0.069 13.7 4.7 30 5.2 0.1 3.7 3 1 1 4 4 4 0 YusW-like protein DUF3349 PF11829.8 EAN30431.1 - 1.9 9.3 9.2 12 6.7 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) VWA_2 PF13519.6 EAN30431.1 - 8.5 7.1 8.4 9.9 6.9 0.8 2.4 1 1 1 2 2 2 0 von Willebrand factor type A domain DUF1430 PF07242.11 EAN30432.1 - 9.8 6.5 10.0 0.089 13.1 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1430) TBPIP PF07106.13 EAN30433.1 - 0.032 14.2 0.5 2.7 8.0 0.0 3.1 3 0 0 3 3 3 0 TBPIP/Hop2 winged helix domain ATP-cone PF03477.16 EAN30433.1 - 0.42 11.2 2.2 2.6 8.7 0.1 2.5 1 1 1 2 2 2 0 ATP cone domain MRVI1 PF05781.12 EAN30433.1 - 7.5 5.1 8.1 1.2 7.7 0.1 2.1 2 0 0 2 2 2 0 MRVI1 protein RuvC PF02075.17 EAN30434.1 - 0.028 14.3 4.3 0.06 13.2 4.3 1.5 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC DUF1664 PF07889.12 EAN30434.1 - 0.25 11.4 10.7 0.77 9.8 4.1 3.2 1 1 0 3 3 3 0 Protein of unknown function (DUF1664) CdvA PF18822.1 EAN30434.1 - 0.36 10.7 4.5 6.5 6.6 0.1 3.0 2 1 0 3 3 3 0 CdvA-like coiled-coil domain PIN_8 PF18476.1 EAN30434.1 - 0.51 10.2 5.6 0.14 12.0 2.4 1.7 2 0 0 2 2 2 0 PIN like domain SesA PF17107.5 EAN30434.1 - 0.53 10.5 6.5 1.2 9.3 4.8 2.4 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sipho_Gp157 PF05565.11 EAN30434.1 - 1.5 8.8 10.5 0.64 10.0 2.3 2.9 2 1 0 3 3 3 0 Siphovirus Gp157 GAS PF13851.6 EAN30434.1 - 2.8 7.2 9.9 0.31 10.4 2.3 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Sigma_reg_N PF13800.6 EAN30435.1 - 0.021 15.1 0.2 0.26 11.6 0.0 2.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Tweety PF04906.13 EAN30435.1 - 0.037 12.7 1.7 0.066 11.9 0.0 2.2 3 0 0 3 3 3 0 Tweety Baculo_PEP_C PF04513.12 EAN30435.1 - 0.95 9.5 5.9 0.57 10.2 0.1 2.9 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FadA PF09403.10 EAN30435.1 - 4.5 7.8 17.4 0.22 12.0 0.5 3.4 3 0 0 3 3 3 0 Adhesion protein FadA HNF-1_N PF04814.13 EAN30436.1 - 0.08 13.6 2.9 0.15 12.6 2.9 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF1430 PF07242.11 EAN30436.1 - 0.24 11.7 4.6 0.076 13.3 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Apolipoprotein PF01442.18 EAN30436.1 - 1.4 8.7 8.7 8.4 6.2 8.7 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain T7SS_ESX_EspC PF10824.8 EAN30436.1 - 7.8 7.0 8.5 1.4 9.4 1.8 2.5 2 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm TBPIP PF07106.13 EAN30438.1 - 0.017 15.1 0.1 1.8 8.6 0.0 2.8 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain DUF1430 PF07242.11 EAN30438.1 - 0.059 13.6 0.4 0.059 13.6 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Het-C PF07217.11 EAN30438.1 - 0.14 10.7 1.8 0.23 10.0 1.8 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C ATP-cone PF03477.16 EAN30438.1 - 0.33 11.6 1.8 2 9.1 0.1 2.5 1 1 1 2 2 2 0 ATP cone domain Apolipoprotein PF01442.18 EAN30438.1 - 0.94 9.3 11.5 3.8 7.3 10.7 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3810 PF12725.7 EAN30439.1 - 0.011 15.2 0.1 0.011 15.2 0.1 2.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3810) COG5 PF10392.9 EAN30439.1 - 0.028 14.6 0.2 0.054 13.7 0.2 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 ATP-cone PF03477.16 EAN30439.1 - 0.19 12.3 0.3 4.2 8.0 0.0 2.4 1 1 1 2 2 2 0 ATP cone domain GspL_C PF12693.7 EAN30439.1 - 0.23 11.3 2.1 0.5 10.2 1.7 1.7 1 1 0 2 2 2 0 GspL periplasmic domain DUF1430 PF07242.11 EAN30439.1 - 0.33 11.2 5.2 0.088 13.1 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF1430 PF07242.11 EAN30440.1 - 0.064 13.5 0.6 0.064 13.5 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF1430 PF07242.11 EAN30441.1 - 0.056 13.7 0.5 0.056 13.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) YusW PF14039.6 EAN30441.1 - 0.069 13.7 4.7 30 5.2 0.1 3.7 3 1 1 4 4 4 0 YusW-like protein DUF3349 PF11829.8 EAN30441.1 - 1.9 9.3 9.2 12 6.7 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) VWA_2 PF13519.6 EAN30441.1 - 8.5 7.1 8.4 9.9 6.9 0.8 2.4 1 1 1 2 2 2 0 von Willebrand factor type A domain DUF1430 PF07242.11 EAN30442.1 - 0.56 10.5 5.2 0.11 12.8 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF1430 PF07242.11 EAN30443.1 - 0.074 13.3 0.6 0.074 13.3 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF3349 PF11829.8 EAN30443.1 - 1.5 9.7 13.9 3.7 8.4 0.8 3.9 2 1 3 5 5 5 0 Protein of unknown function (DUF3349) Transcrip_act PF04949.13 EAN30444.1 - 0.052 13.4 0.1 0.31 10.9 0.0 2.0 1 1 1 2 2 2 0 Transcriptional activator DUF1430 PF07242.11 EAN30444.1 - 1.3 9.4 4.9 0.39 11.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF1430 PF07242.11 EAN30445.1 - 0.038 14.3 1.0 0.038 14.3 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Baculo_PEP_C PF04513.12 EAN30445.1 - 0.4 10.7 10.7 0.7 9.9 1.2 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3349 PF11829.8 EAN30445.1 - 0.43 11.4 11.0 15 6.4 0.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3349) HTH_57 PF18679.1 EAN30445.1 - 0.95 9.8 4.4 2.7 8.4 0.2 3.0 3 0 0 3 3 3 0 ThcOx helix turn helix domain SurA_N PF09312.11 EAN30445.1 - 1.7 8.8 5.6 0.33 11.0 1.1 2.1 3 0 0 3 3 3 0 SurA N-terminal domain Apolipoprotein PF01442.18 EAN30445.1 - 2.2 8.1 6.8 13 5.6 6.8 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HNF-1_N PF04814.13 EAN30446.1 - 0.08 13.6 2.9 0.15 12.6 2.9 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF1430 PF07242.11 EAN30446.1 - 0.24 11.7 4.6 0.076 13.3 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Apolipoprotein PF01442.18 EAN30446.1 - 1.4 8.7 8.7 8.4 6.2 8.7 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain T7SS_ESX_EspC PF10824.8 EAN30446.1 - 7.8 7.0 8.5 1.4 9.4 1.8 2.5 2 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Sigma_reg_N PF13800.6 EAN30447.1 - 0.021 15.1 0.2 0.26 11.6 0.0 2.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Tweety PF04906.13 EAN30447.1 - 0.037 12.7 1.7 0.066 11.9 0.0 2.2 3 0 0 3 3 3 0 Tweety Baculo_PEP_C PF04513.12 EAN30447.1 - 0.95 9.5 5.9 0.57 10.2 0.1 2.9 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FadA PF09403.10 EAN30447.1 - 4.5 7.8 17.4 0.22 12.0 0.5 3.4 3 0 0 3 3 3 0 Adhesion protein FadA RuvC PF02075.17 EAN30448.1 - 0.027 14.3 4.3 0.06 13.2 4.3 1.6 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC DUF1664 PF07889.12 EAN30448.1 - 0.25 11.4 10.7 0.77 9.8 4.1 3.2 1 1 0 3 3 3 0 Protein of unknown function (DUF1664) CdvA PF18822.1 EAN30448.1 - 0.36 10.7 4.5 6.5 6.6 0.1 3.0 2 1 0 3 3 3 0 CdvA-like coiled-coil domain PIN_8 PF18476.1 EAN30448.1 - 0.51 10.2 5.6 0.14 12.0 2.4 1.7 2 0 0 2 2 2 0 PIN like domain SesA PF17107.5 EAN30448.1 - 0.53 10.5 6.5 1.2 9.3 4.8 2.4 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sipho_Gp157 PF05565.11 EAN30448.1 - 1.5 8.8 10.5 0.64 10.0 2.3 2.9 2 1 0 3 3 3 0 Siphovirus Gp157 GAS PF13851.6 EAN30448.1 - 2.8 7.2 9.9 0.31 10.4 2.3 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1430 PF07242.11 EAN30449.1 - 0.53 10.6 4.7 0.11 12.7 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Sigma_reg_N PF13800.6 EAN30450.1 - 0.0002 21.6 0.8 0.0023 18.2 0.0 3.0 3 0 0 3 3 3 1 Sigma factor regulator N-terminal DUF2207 PF09972.9 EAN30450.1 - 0.0026 16.6 1.3 0.0026 16.6 1.3 3.5 1 1 2 4 4 4 2 Predicted membrane protein (DUF2207) DUF2130 PF09903.9 EAN30450.1 - 0.67 9.2 9.0 0.13 11.5 3.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) Syntaxin_2 PF14523.6 EAN30450.1 - 2.6 8.5 12.5 10 6.6 3.0 3.4 3 1 0 3 3 3 0 Syntaxin-like protein DUF948 PF06103.11 EAN30450.1 - 2.9 8.2 6.6 2.5 8.4 0.2 3.7 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Peptidase_M4_C PF02868.15 EAN30450.1 - 8.8 6.2 10.0 5.5 6.8 0.1 3.0 2 1 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain DUF1430 PF07242.11 EAN30451.1 - 0.053 13.8 0.4 0.053 13.8 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1430) HNF-1_N PF04814.13 EAN30451.1 - 0.67 10.5 4.8 0.52 10.9 3.1 1.6 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus TBPIP PF07106.13 EAN30452.1 - 2.6 8.0 4.0 70 3.5 0.0 3.8 4 1 0 4 4 4 0 TBPIP/Hop2 winged helix domain NACHT_N PF17100.5 EAN30452.1 - 5.9 6.7 5.8 0.73 9.7 0.8 1.9 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase DUF1430 PF07242.11 EAN30452.1 - 9.5 6.6 9.6 0.097 12.9 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1430) DUF1430 PF07242.11 EAN30453.1 - 0.32 11.3 3.5 0.12 12.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) RNase_J_C PF17770.1 EAN30453.1 - 0.65 11.1 2.5 47 5.1 0.1 3.3 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain DUF1430 PF07242.11 EAN30454.1 - 0.046 14.0 0.4 0.046 14.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) TBPIP PF07106.13 EAN30455.1 - 0.05 13.6 0.1 1.6 8.7 0.0 3.1 3 0 0 3 3 3 0 TBPIP/Hop2 winged helix domain FtsX PF02687.21 EAN30455.1 - 0.053 14.0 2.7 0.3 11.6 2.0 2.2 2 0 0 2 2 2 0 FtsX-like permease family T7SS_ESX_EspC PF10824.8 EAN30455.1 - 2.1 8.9 6.8 3.9 8.0 3.4 2.4 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Pex24p PF06398.11 EAN30455.1 - 2.5 7.0 3.9 0.41 9.6 0.1 1.5 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin PSK_trans_fac PF07704.11 EAN30455.1 - 5.9 7.7 8.0 20 6.0 2.2 2.7 2 1 1 3 3 3 0 Rv0623-like transcription factor DUF1430 PF07242.11 EAN30456.1 - 0.06 13.6 0.4 0.06 13.6 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) TBPIP PF07106.13 EAN30456.1 - 0.38 10.7 2.8 47 4.0 0.0 3.9 4 0 0 4 4 4 0 TBPIP/Hop2 winged helix domain DUF1430 PF07242.11 EAN30457.1 - 0.081 13.2 0.6 0.081 13.2 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) TBPIP PF07106.13 EAN30458.1 - 0.23 11.4 1.2 11 6.1 0.3 3.1 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain Sigma_reg_N PF13800.6 EAN30458.1 - 0.87 9.9 5.6 8.5 6.7 0.0 3.4 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Collectrin PF16959.5 EAN30458.1 - 1.4 8.7 6.5 17 5.2 4.0 2.5 2 0 0 2 2 2 0 Renal amino acid transporter Condensation PF00668.20 EAN30459.1 - 0.14 10.8 0.2 0.14 10.8 0.2 1.1 1 0 0 1 1 1 0 Condensation domain EMG1 PF03587.14 EAN30460.1 - 2.9e-28 98.8 0.9 4.6e-28 98.2 0.9 1.4 1 1 0 1 1 1 1 EMG1/NEP1 methyltransferase LRR_5 PF13306.6 EAN30460.1 - 0.0016 18.4 5.0 0.0038 17.2 5.0 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Plus-3 PF03126.18 EAN30461.1 - 0.062 13.8 0.2 5.7 7.5 0.0 3.1 2 1 0 2 2 2 0 Plus-3 domain ubiquitin PF00240.23 EAN30463.1 - 2.8e-07 30.2 0.4 6.9e-07 28.9 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EAN30463.1 - 0.00034 21.0 0.2 0.0019 18.6 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EAN30463.1 - 0.019 15.0 0.5 0.15 12.1 0.2 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain Rad60-SLD PF11976.8 EAN30463.1 - 0.075 12.9 0.7 0.3 10.9 0.7 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DHHC PF01529.20 EAN30464.1 - 5.3e-35 120.5 10.2 5.3e-35 120.5 10.2 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF4013 PF13197.6 EAN30464.1 - 0.00011 22.2 3.5 0.00011 22.2 3.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4013) DnaJ PF00226.31 EAN30466.1 - 1.1e-19 70.2 1.4 2.1e-12 47.0 0.3 2.3 1 1 0 2 2 2 2 DnaJ domain DUF3395 PF11875.8 EAN30467.1 - 3.6e-10 40.0 0.0 7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) IPK PF03770.16 EAN30468.1 - 1.7e-23 83.5 0.6 3.7e-23 82.4 0.6 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase DUF3847 PF12958.7 EAN30468.1 - 0.29 11.3 0.1 0.29 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Rib_5-P_isom_A PF06026.14 EAN30469.1 - 2e-52 177.3 0.0 3.6e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) ISG65-75 PF11727.8 EAN30469.1 - 0.00034 19.9 1.1 0.00055 19.3 1.1 1.2 1 0 0 1 1 1 1 Invariant surface glycoprotein DeoRC PF00455.22 EAN30469.1 - 0.0046 16.9 0.5 0.41 10.6 0.5 2.3 1 1 0 1 1 1 1 DeoR C terminal sensor domain Synaptobrevin PF00957.21 EAN30469.1 - 0.0061 16.3 0.2 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 Synaptobrevin DUF4140 PF13600.6 EAN30469.1 - 0.0074 16.7 0.6 0.3 11.5 0.0 2.7 3 0 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) Dynactin_p22 PF07426.11 EAN30469.1 - 0.015 15.2 0.8 0.03 14.2 0.8 1.5 1 0 0 1 1 1 0 Dynactin subunit p22 WEMBL PF05701.11 EAN30469.1 - 0.021 13.5 0.9 0.032 12.9 0.9 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light EzrA PF06160.12 EAN30469.1 - 0.051 11.8 1.3 0.073 11.2 1.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Laminin_II PF06009.12 EAN30469.1 - 0.1 12.6 1.4 0.4 10.7 0.3 2.2 1 1 1 2 2 2 0 Laminin Domain II SKA2 PF16740.5 EAN30469.1 - 0.11 12.3 0.7 0.31 10.8 0.4 1.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF4315 PF14193.6 EAN30469.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Fzo_mitofusin PF04799.13 EAN30469.1 - 0.38 10.3 3.4 8 6.0 0.2 2.4 1 1 1 2 2 2 0 fzo-like conserved region FlaC_arch PF05377.11 EAN30469.1 - 1.8 9.0 4.4 22 5.5 0.2 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) E3_UFM1_ligase PF09743.9 EAN30470.1 - 1.9e-69 234.4 1.0 3.5e-69 233.5 1.0 1.4 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 SRI PF08236.11 EAN30470.1 - 0.74 10.0 8.1 0.17 12.1 0.3 3.3 3 1 1 4 4 4 0 SRI (Set2 Rpb1 interacting) domain SGS PF05002.15 EAN30471.1 - 7.8e-05 22.7 0.7 0.00014 21.9 0.2 1.6 2 0 0 2 2 2 1 SGS domain CS PF04969.16 EAN30471.1 - 0.00017 22.5 0.9 0.00031 21.7 0.9 1.4 1 0 0 1 1 1 1 CS domain CTP_transf_like PF01467.26 EAN30472.1 - 2.3e-10 40.8 0.0 3.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like mRNA_cap_C PF03919.15 EAN30477.1 - 0.023 15.3 1.5 0.049 14.3 1.5 1.6 1 1 0 1 1 1 0 mRNA capping enzyme, C-terminal domain tRNA_synt_1c_R1 PF04558.15 EAN30477.1 - 0.082 12.9 0.6 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Colicin_immun PF09204.10 EAN30477.1 - 4.4 7.9 6.0 14 6.3 0.5 3.1 1 1 2 3 3 3 0 Bacterial self-protective colicin-like immunity partial_CstF PF15861.5 EAN30478.1 - 0.11 12.4 0.3 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain FAINT PF04385.15 EAN30479.1 - 0.029 14.4 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function, DUF529 BACK PF07707.15 EAN30481.1 - 9.9e-07 28.8 0.1 2.9e-06 27.3 0.1 1.8 1 1 0 1 1 1 1 BTB And C-terminal Kelch Sde2_N_Ubi PF13019.6 EAN30483.1 - 4.2e-18 65.7 1.3 5.8e-18 65.2 1.2 1.4 1 1 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain PRELI PF04707.14 EAN30484.1 - 1.8e-12 47.3 0.0 2.3e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Helicase_C_2 PF13307.6 EAN30485.1 - 2e-43 148.5 0.2 7.2e-43 146.7 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 EAN30485.1 - 2.8e-36 124.8 0.5 2.8e-36 124.8 0.5 2.4 3 0 0 3 3 3 1 DEAD_2 DEAD PF00270.29 EAN30485.1 - 0.00013 21.8 0.2 0.0039 17.0 0.1 3.0 3 1 0 3 3 3 1 DEAD/DEAH box helicase HBB PF06777.11 EAN30485.1 - 0.00033 20.4 1.2 0.0008 19.1 0.6 2.0 2 0 0 2 2 2 1 Helical and beta-bridge domain ResIII PF04851.15 EAN30485.1 - 0.013 15.5 0.3 4.1 7.4 0.0 3.1 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Synaptobrevin PF00957.21 EAN30486.1 - 1.2 9.0 6.0 0.37 10.6 2.3 2.0 1 1 1 2 2 2 0 Synaptobrevin YkyA PF10368.9 EAN30486.1 - 5.2 6.7 8.6 0.95 9.1 4.3 1.7 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein SAC3_GANP PF03399.16 EAN30487.1 - 3.3e-10 39.8 21.2 6.9e-07 28.9 21.2 3.1 1 1 0 1 1 1 1 SAC3/GANP family DUF4585 PF15232.6 EAN30487.1 - 0.072 13.2 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4585) CSN8_PSD8_EIF3K PF10075.9 EAN30487.1 - 0.19 11.7 5.3 0.32 11.0 0.0 2.8 2 1 0 2 2 2 0 CSN8/PSMD8/EIF3K family CC2-LZ PF16516.5 EAN30488.1 - 0.01 16.2 14.1 0.01 16.2 14.1 3.0 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ZapB PF06005.12 EAN30488.1 - 0.37 11.3 44.7 0.54 10.7 1.3 5.6 2 1 2 5 5 5 0 Cell division protein ZapB Integrase_DNA PF02920.15 EAN30488.1 - 0.99 9.2 4.9 24 4.7 1.9 2.8 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase ATG16 PF08614.11 EAN30488.1 - 3.2 7.9 40.2 4.9 7.3 35.8 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MOZART1 PF12554.8 EAN30489.1 - 4.1e-14 52.1 1.0 5.7e-14 51.6 1.0 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.7 EAN30489.1 - 0.027 14.1 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated CENP-H PF05837.12 EAN30490.1 - 0.19 12.2 0.1 0.19 12.2 0.1 4.1 4 1 1 5 5 5 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 EAN30490.1 - 0.2 11.0 11.4 0.14 11.4 1.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 EAN30490.1 - 0.87 9.3 5.4 2 8.2 0.1 2.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF4201 PF13870.6 EAN30490.1 - 3.9 7.2 28.5 0.09 12.5 18.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF948 PF06103.11 EAN30490.1 - 4.1 7.7 7.3 16 5.9 0.2 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) RRM_1 PF00076.22 EAN30491.1 - 2.1e-13 49.9 0.0 2.4e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAN30491.1 - 2.5e-05 24.2 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 EAN30491.1 - 0.036 14.1 0.1 0.069 13.2 0.1 1.5 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SH2_2 PF14633.6 EAN30492.1 - 1.1e-15 57.6 0.2 1.1e-15 57.6 0.2 3.4 4 0 0 4 4 4 2 SH2 domain HTH_44 PF14641.6 EAN30492.1 - 1e-07 32.4 0.8 5.5e-07 30.0 0.8 2.3 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EAN30492.1 - 4.9e-05 23.6 1.9 0.027 14.8 0.2 3.0 1 1 1 2 2 2 2 Helix-hairpin-helix motif AAA_11 PF13086.6 EAN30495.1 - 1.1e-42 146.6 0.0 9.8e-26 91.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 EAN30495.1 - 1.7e-42 145.3 0.8 1.8e-23 83.2 0.1 2.8 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 EAN30495.1 - 6.9e-11 42.7 0.0 1.6e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAN30495.1 - 5.5e-09 36.0 0.0 2.1e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EAN30495.1 - 3.4e-05 23.9 0.0 0.00011 22.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 EAN30495.1 - 9.5e-05 23.0 0.5 0.0043 17.7 0.0 3.3 3 0 0 3 3 3 1 Double-stranded RNA binding motif NACHT PF05729.12 EAN30495.1 - 0.0011 18.8 0.0 0.0043 17.0 0.0 2.0 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 EAN30495.1 - 0.0039 16.5 0.2 0.81 8.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EAN30495.1 - 0.012 15.1 0.0 0.27 10.7 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 EAN30495.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DEAD PF00270.29 EAN30495.1 - 0.049 13.4 0.0 0.17 11.6 0.0 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 EAN30495.1 - 0.052 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EAN30495.1 - 0.073 13.5 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAN30495.1 - 0.15 11.6 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Alba PF01918.21 EAN30496.1 - 3.9e-17 61.8 0.1 7.3e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 Alba Steroid_dh PF02544.16 EAN30497.1 - 1.1e-32 113.1 11.6 1.9e-32 112.3 11.6 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase YukD PF08817.10 EAN30497.1 - 0.12 13.1 0.0 0.18 12.5 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD zf-RanBP PF00641.18 EAN30499.1 - 6.5e-05 22.2 2.4 9.5e-05 21.6 2.4 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DOT1 PF08123.13 EAN30500.1 - 0.0011 18.5 0.1 0.0032 17.0 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 UDPG_MGDP_dh PF00984.19 EAN30500.1 - 0.03 14.5 0.2 0.071 13.3 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain PCMT PF01135.19 EAN30500.1 - 0.057 13.2 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FAINT PF04385.15 EAN30501.1 - 7.8e-29 99.6 26.5 5e-07 29.7 0.8 6.2 6 0 0 6 6 6 5 Domain of unknown function, DUF529 Cullin_Nedd8 PF10557.9 EAN30502.1 - 0.027 14.5 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Cullin protein neddylation domain MarR_2 PF12802.7 EAN30502.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 MarR family RQC PF09382.10 EAN30502.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 RQC domain Cullin PF00888.22 EAN30503.1 - 4.7e-25 88.3 16.2 8.9e-17 60.9 11.4 2.7 2 1 0 2 2 2 2 Cullin family I_LWEQ PF01608.17 EAN30505.1 - 0.0098 16.1 27.4 0.1 12.9 1.9 3.9 1 1 1 3 3 3 1 I/LWEQ domain HTH_37 PF13744.6 EAN30505.1 - 0.14 12.1 17.9 0.26 11.3 0.8 3.9 1 1 3 4 4 4 0 Helix-turn-helix domain MerR-DNA-bind PF09278.11 EAN30505.1 - 0.16 12.5 0.2 0.16 12.5 0.2 4.4 2 1 3 5 5 5 0 MerR, DNA binding GAS PF13851.6 EAN30505.1 - 0.17 11.2 28.2 0.16 11.3 18.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FlxA PF14282.6 EAN30505.1 - 0.17 11.9 23.4 0.36 10.8 3.3 2.8 1 1 2 3 3 3 0 FlxA-like protein ABC_tran_CTD PF16326.5 EAN30505.1 - 0.18 12.1 33.0 6.4 7.1 0.0 4.4 2 1 3 5 5 5 0 ABC transporter C-terminal domain YvrJ PF12841.7 EAN30505.1 - 0.47 10.0 0.1 0.47 10.0 0.1 3.2 5 0 0 5 5 5 0 YvrJ protein family DUF4061 PF13270.6 EAN30505.1 - 0.64 10.4 18.2 1.9 8.9 3.0 3.2 1 1 2 4 4 4 0 Domain of unknown function (DUF4061) DUF3584 PF12128.8 EAN30505.1 - 0.86 7.0 32.1 1.1 6.7 32.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.11 EAN30505.1 - 3.2 8.2 8.1 83 3.7 0.1 4.5 4 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Osmo_CC PF08946.10 EAN30505.1 - 3.3 8.0 5.5 5 7.4 0.0 3.1 4 0 0 4 4 4 0 Osmosensory transporter coiled coil Exonuc_VII_L PF02601.15 EAN30505.1 - 4.4 6.8 22.9 19 4.7 22.9 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4315 PF14193.6 EAN30505.1 - 9.4 6.3 28.3 5.8 7.0 1.0 4.4 1 1 2 4 4 4 0 Domain of unknown function (DUF4315) Rer1 PF03248.13 EAN30506.1 - 1.2e-57 194.3 13.1 1.6e-57 194.0 13.1 1.0 1 0 0 1 1 1 1 Rer1 family DC_STAMP PF07782.13 EAN30506.1 - 0.051 13.4 11.9 0.073 12.9 0.0 3.0 2 1 1 3 3 3 0 DC-STAMP-like protein DUF4229 PF14012.6 EAN30506.1 - 4.6 7.4 12.3 1 9.5 8.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF1430 PF07242.11 EAN30506.1 - 9.1 6.6 13.7 1.2 9.5 5.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Ras PF00071.22 EAN30507.1 - 5.9e-46 156.0 0.3 7.1e-46 155.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAN30507.1 - 3.2e-22 79.0 0.1 4.9e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAN30507.1 - 6.5e-09 35.5 0.0 7.4e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAN30507.1 - 0.00036 20.1 0.0 0.00074 19.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DEAD PF00270.29 EAN30508.1 - 1.2e-16 61.0 0.0 3.9e-16 59.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAN30508.1 - 5.5e-10 39.5 0.0 3.1e-09 37.1 0.0 2.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAN30508.1 - 6.2e-05 23.3 0.2 0.00043 20.6 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SICA_beta PF12878.7 EAN30508.1 - 0.094 12.9 0.8 0.35 11.0 0.8 2.0 1 0 0 1 1 1 0 SICA extracellular beta domain MFA1_2 PF17317.2 EAN30508.1 - 0.77 9.6 2.5 2.7 7.8 2.5 2.0 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 Chorein_N PF12624.7 EAN30509.1 - 4.4e-29 100.9 0.1 2.3e-28 98.6 0.1 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 EAN30509.1 - 1.1e-06 28.7 2.7 1.1e-06 28.7 2.7 3.1 3 1 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal ATG_C PF09333.11 EAN30510.1 - 8.6e-07 29.2 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EAN30510.1 - 1.5 8.6 6.9 32 4.2 0.0 3.7 4 0 0 4 4 4 0 Vacuolar-sorting-associated 13 protein C-terminal Cytomega_UL20A PF05984.12 EAN30512.1 - 0.034 14.5 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Pyr_redox_2 PF07992.14 EAN30513.1 - 6.9e-42 143.7 0.0 1e-41 143.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAN30513.1 - 2.5e-15 56.8 1.5 3.3e-13 50.0 0.5 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EAN30513.1 - 3.9e-15 55.6 0.0 9.7e-14 51.1 0.0 2.6 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Reductase_C PF14759.6 EAN30513.1 - 6.4e-09 36.3 0.0 6.4e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Reductase C-terminal Rieske_2 PF13806.6 EAN30513.1 - 1.6e-05 24.8 0.0 8.3e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.6 EAN30513.1 - 0.00011 21.5 0.8 0.00048 19.5 0.3 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAN30513.1 - 0.0019 17.3 0.6 0.22 10.5 0.0 3.2 2 1 1 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EAN30513.1 - 0.0048 16.9 0.3 0.045 13.7 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding ApbA PF02558.16 EAN30513.1 - 0.023 14.4 0.2 0.071 12.8 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EAN30513.1 - 0.11 12.8 0.6 2.9 8.2 0.2 3.0 2 1 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.12 EAN30513.1 - 0.15 11.1 0.1 4.9 6.1 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein Glyco_trans_4_5 PF16994.5 EAN30513.1 - 0.19 11.3 0.1 0.34 10.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl-transferase family 4 DUF3228 PF11539.8 EAN30514.1 - 1.1e-72 243.7 0.0 1.4e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) LYTB PF02401.18 EAN30515.1 - 1.2e-80 270.5 0.8 1.4e-80 270.3 0.8 1.0 1 0 0 1 1 1 1 LytB protein PCP PF02429.15 EAN30515.1 - 0.033 14.5 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein UCH PF00443.29 EAN30516.1 - 2.8e-28 99.1 3.7 2.8e-28 99.1 3.7 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAN30516.1 - 2.4e-10 40.5 15.1 1.3e-05 25.0 1.4 3.4 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase TAXi_N PF14543.6 EAN30517.1 - 1.4e-20 74.3 2.3 1.4e-20 74.3 2.3 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.23 EAN30517.1 - 1.7e-20 73.7 4.3 1.1e-19 71.0 4.3 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EAN30517.1 - 9.2e-05 22.3 0.1 0.0035 17.1 0.1 2.7 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal RCC1 PF00415.18 EAN30518.1 - 7.7e-38 128.9 6.7 7e-10 39.4 0.0 7.3 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAN30518.1 - 1.2e-16 60.0 26.0 2.7e-06 27.0 0.7 7.0 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat eIF2A PF08662.11 EAN30518.1 - 0.048 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A zf-RanBP PF00641.18 EAN30518.1 - 0.09 12.1 8.2 0.21 10.9 8.2 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others PQQ_3 PF13570.6 EAN30518.1 - 0.54 10.8 2.0 2.6 8.6 0.1 3.0 3 0 0 3 3 3 0 PQQ-like domain SurA_N_3 PF13624.6 EAN30519.1 - 0.0085 15.9 0.2 0.013 15.3 0.2 1.3 1 0 0 1 1 1 1 SurA N-terminal domain DUF1013 PF06242.11 EAN30519.1 - 0.075 13.1 2.5 0.14 12.2 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) Herpes_capsid PF06112.11 EAN30519.1 - 2.9 7.9 5.3 2.1 8.4 3.7 1.5 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein ATP-synt_E PF05680.12 EAN30519.1 - 3 8.3 7.8 5.9 7.3 7.8 1.4 1 0 0 1 1 1 0 ATP synthase E chain Got1 PF04178.12 EAN30520.1 - 5.4e-25 88.0 21.4 7.5e-25 87.5 21.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 EAN30520.1 - 2.1 6.5 15.2 3.1 6.0 15.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UPF0239 PF06783.11 EAN30521.1 - 0.019 15.1 0.1 0.038 14.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Tugs PF17840.1 EAN30521.1 - 0.032 14.4 0.2 0.057 13.6 0.2 1.3 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain CSN5_C PF18323.1 EAN30522.1 - 0.041 14.8 0.1 0.041 14.8 0.1 3.4 2 1 1 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain Bmp PF02608.14 EAN30522.1 - 0.076 12.0 5.2 0.026 13.5 1.8 1.8 2 0 0 2 2 2 0 ABC transporter substrate-binding protein PnrA-like ATP-cone PF03477.16 EAN30522.1 - 0.7 10.5 4.4 1.7 9.3 0.0 2.9 3 1 0 3 3 3 0 ATP cone domain HI0933_like PF03486.14 EAN30522.1 - 7.8 5.1 8.9 2.2 6.9 2.6 2.1 2 0 0 2 2 2 0 HI0933-like protein Paf1 PF03985.13 EAN30523.1 - 1.3e-09 37.6 9.1 1.6e-07 30.7 7.1 2.6 2 1 0 2 2 2 2 Paf1 Ribosomal_L23 PF00276.20 EAN30524.1 - 1e-13 51.4 0.3 1e-13 51.4 0.3 3.0 2 2 1 3 3 3 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 EAN30524.1 - 0.0002 21.5 15.5 0.00029 21.0 12.9 2.2 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Terminase_3C PF17288.2 EAN30524.1 - 0.014 15.8 1.1 0.018 15.5 1.1 1.2 1 0 0 1 1 1 0 Terminase RNAseH like domain Myc_N PF01056.18 EAN30524.1 - 0.065 13.1 1.3 0.074 12.9 1.3 1.0 1 0 0 1 1 1 0 Myc amino-terminal region DUF1189 PF06691.11 EAN30524.1 - 0.089 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) DUF1198 PF06711.11 EAN30524.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) Acetyltransf_1 PF00583.25 EAN30525.1 - 1.2e-09 38.5 0.0 1.4e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAN30525.1 - 0.0046 16.9 0.0 0.0057 16.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAN30525.1 - 0.015 15.7 0.0 0.02 15.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EAN30525.1 - 0.031 13.7 0.6 0.031 13.7 0.6 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase FR47 PF08445.10 EAN30525.1 - 0.047 13.7 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein V-ATPase_G PF03179.15 EAN30527.1 - 0.0013 19.3 0.9 0.0014 19.1 0.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit PDEase_I PF00233.19 EAN30527.1 - 0.082 12.6 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Vps52 PF04129.12 EAN30528.1 - 1.6e-11 43.6 3.7 2.6e-11 42.9 3.7 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family BST2 PF16716.5 EAN30528.1 - 0.0086 16.6 2.5 0.0086 16.6 2.5 2.2 1 1 1 2 2 2 1 Bone marrow stromal antigen 2 DUF5633 PF18656.1 EAN30528.1 - 0.014 15.3 0.0 0.059 13.3 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5633) PriC PF07445.12 EAN30528.1 - 0.024 14.6 1.3 0.024 14.6 1.3 1.6 2 0 0 2 2 2 0 Primosomal replication protein priC FHIPEP PF00771.20 EAN30528.1 - 0.034 12.6 0.6 0.042 12.3 0.6 1.1 1 0 0 1 1 1 0 FHIPEP family DUF2671 PF10877.8 EAN30528.1 - 0.061 13.1 1.4 0.17 11.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2671) Prominin PF05478.11 EAN30528.1 - 0.16 9.9 5.8 0.2 9.5 3.0 2.0 1 1 1 2 2 2 0 Prominin Sec20 PF03908.13 EAN30528.1 - 0.23 11.4 2.4 0.46 10.4 0.5 2.4 2 1 0 3 3 3 0 Sec20 DUF3552 PF12072.8 EAN30528.1 - 0.8 9.1 9.8 1.3 8.4 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF16 PF01519.16 EAN30528.1 - 2.3 8.7 9.7 0.3 11.6 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Med30 PF11315.8 EAN30528.1 - 2.5 8.3 8.2 50 4.1 8.1 2.3 1 1 1 2 2 2 0 Mediator complex subunit 30 Vps52 PF04129.12 EAN30529.1 - 6.7e-16 58.1 16.2 1e-15 57.5 16.2 1.3 1 0 0 1 1 1 1 Vps52 / Sac2 family DUF3273 PF11677.8 EAN30530.1 - 2.1e-104 348.5 8.8 2.4e-104 348.3 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) RRM_1 PF00076.22 EAN30532.1 - 6.4e-40 134.8 0.8 1.2e-13 50.7 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 EAN30532.1 - 1.4e-05 25.0 0.4 0.013 15.3 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF1866) RRM_3 PF08777.11 EAN30532.1 - 0.0029 17.6 7.0 0.2 11.7 0.3 3.8 4 1 1 5 5 5 2 RNA binding motif RRM_occluded PF16842.5 EAN30532.1 - 0.0038 17.0 0.1 7 6.6 0.0 3.5 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EAN30532.1 - 0.013 15.6 9.9 0.53 10.4 0.1 4.0 4 0 0 4 4 4 0 Limkain b1 Nup35_RRM_2 PF14605.6 EAN30532.1 - 0.044 13.8 0.2 48 4.1 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Topoisom_bac PF01131.20 EAN30533.1 - 1.7e-93 313.9 0.0 1.6e-69 234.9 0.0 2.1 1 1 1 2 2 2 2 DNA topoisomerase Toprim PF01751.22 EAN30533.1 - 1e-09 38.6 0.1 1.9e-08 34.4 0.1 2.7 2 1 0 2 2 2 1 Toprim domain TAF PF02969.17 EAN30534.1 - 1.3e-07 31.6 0.2 6.9e-06 26.1 0.2 2.6 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 EAN30534.1 - 7.6e-05 23.0 0.0 0.00025 21.3 0.0 1.9 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Paramyx_P_V_C PF03210.13 EAN30534.1 - 0.041 13.7 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Ham1p_like PF01725.16 EAN30536.1 - 4.5e-20 72.4 0.0 5e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Ham1 family Ribosomal_S3Ae PF01015.18 EAN30538.1 - 5e-87 290.7 1.1 6e-87 290.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family GTP_EFTU PF00009.27 EAN30539.1 - 6.6e-55 185.7 0.0 9.2e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EAN30539.1 - 1.2e-19 70.7 0.0 3.8e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EAN30539.1 - 4.9e-17 62.1 5.2 8.8e-17 61.3 5.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAN30539.1 - 5.8e-05 23.1 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAN30539.1 - 0.028 14.3 0.0 0.087 12.7 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 EAN30539.1 - 0.029 14.1 0.5 7.1 6.3 0.5 3.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EAN30539.1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Polyoma_lg_T_C PF06431.11 EAN30539.1 - 0.13 11.1 0.1 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus GTP_EFTU_D4 PF14578.6 EAN30539.1 - 0.18 11.7 2.9 0.46 10.4 2.9 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Pkinase PF00069.25 EAN30540.1 - 9.7e-06 25.1 0.2 1e-05 25.0 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EAN30540.1 - 0.021 14.2 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 EAN30540.1 - 0.026 13.8 0.2 0.028 13.7 0.2 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase SRP40_C PF05022.12 EAN30541.1 - 1.2e-18 67.7 2.6 1.2e-18 67.7 2.6 2.4 3 1 0 3 3 3 1 SRP40, C-terminal domain Phage_DsbA PF11126.8 EAN30541.1 - 0.26 11.5 5.9 0.58 10.4 0.8 2.4 2 1 0 2 2 2 0 Transcriptional regulator DsbA Pkinase PF00069.25 EAN30542.1 - 3.6e-39 134.7 11.0 1e-18 67.7 0.0 3.8 2 1 1 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 EAN30542.1 - 3.3e-15 56.1 6.3 1.8e-08 34.0 0.0 3.8 3 1 1 4 4 4 2 Protein tyrosine kinase Kdo PF06293.14 EAN30542.1 - 0.0067 15.8 0.1 0.014 14.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ins_P5_2-kin PF06090.12 EAN30543.1 - 5.7e-10 39.1 1.3 8.5e-10 38.6 1.3 1.4 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Calx-beta PF03160.14 EAN30543.1 - 0.016 15.4 0.0 0.048 13.8 0.0 1.8 1 0 0 1 1 1 0 Calx-beta domain DUF3523 PF12037.8 EAN30544.1 - 3.6e-90 301.9 25.9 4.7e-90 301.6 25.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 EAN30544.1 - 4.3e-23 82.2 0.0 1.1e-22 80.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAN30544.1 - 8.7e-06 25.6 0.0 3e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EAN30544.1 - 1.3e-05 25.6 1.4 0.015 15.7 0.0 3.1 3 1 1 4 4 3 2 AAA ATPase domain Mg_chelatase PF01078.21 EAN30544.1 - 0.0016 17.8 0.5 0.017 14.5 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EAN30544.1 - 0.0018 18.0 0.1 0.0018 18.0 0.1 2.0 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 EAN30544.1 - 0.0018 18.4 0.4 0.0059 16.7 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 EAN30544.1 - 0.0058 16.2 0.9 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EAN30544.1 - 0.0064 16.8 7.3 0.029 14.7 0.1 3.3 2 2 1 4 4 4 1 AAA domain AAA_33 PF13671.6 EAN30544.1 - 0.0074 16.5 0.3 0.026 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EAN30544.1 - 0.0079 15.9 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 EAN30544.1 - 0.01 15.2 0.0 0.01 15.2 0.0 2.7 4 0 0 4 4 4 1 KaiC AAA_lid_3 PF17862.1 EAN30544.1 - 0.011 15.6 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA+ lid domain RNA_helicase PF00910.22 EAN30544.1 - 0.014 15.8 0.0 0.055 13.9 0.0 2.2 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 EAN30544.1 - 0.024 14.6 6.0 0.028 14.4 0.5 3.5 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EAN30544.1 - 0.024 15.2 0.1 0.024 15.2 0.1 3.3 2 2 0 2 2 1 0 AAA domain Zot PF05707.12 EAN30544.1 - 0.058 13.0 0.0 0.058 13.0 0.0 3.2 2 2 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_25 PF13481.6 EAN30544.1 - 0.1 12.2 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EAN30544.1 - 0.18 11.8 0.0 0.18 11.8 0.0 2.3 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2909 PF11137.8 EAN30544.1 - 0.2 11.6 0.1 0.45 10.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) AAA_11 PF13086.6 EAN30544.1 - 0.59 9.9 0.0 0.59 9.9 0.0 3.3 2 1 1 3 3 3 0 AAA domain PYC_OADA PF02436.18 EAN30544.1 - 3 7.5 11.6 6.1 6.5 11.6 1.5 1 1 0 1 1 1 0 Conserved carboxylase domain Ribosomal_L28e PF01778.17 EAN30545.1 - 1.4e-30 106.4 0.6 1.4e-30 106.4 0.6 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EAN30545.1 - 3.9e-17 62.7 10.0 3.9e-17 62.7 10.0 1.6 2 0 0 2 2 2 1 Mak16 protein C-terminal region CinA_KH PF18146.1 EAN30545.1 - 0.024 14.8 0.1 0.055 13.6 0.1 1.6 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain DUF5595 PF18077.1 EAN30546.1 - 0.075 13.1 0.3 0.91 9.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) Met_10 PF02475.16 EAN30550.1 - 3.7e-41 141.1 3.5 1.2e-24 87.1 0.2 2.3 2 0 0 2 2 2 2 Met-10+ like-protein TRM PF02005.16 EAN30550.1 - 0.00093 18.5 0.2 0.0015 17.8 0.2 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.10 EAN30550.1 - 0.0014 18.3 0.1 0.0039 16.8 0.1 1.8 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.15 EAN30550.1 - 0.0017 18.1 0.1 0.0017 18.1 0.1 2.1 3 0 0 3 3 3 1 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.13 EAN30550.1 - 0.0038 16.7 0.0 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 EAN30550.1 - 0.019 14.6 0.0 0.054 13.1 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Ribosomal_S17e PF00833.18 EAN30551.1 - 1.4e-58 196.1 0.4 1.6e-58 195.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 Arm-DNA-bind_2 PF12167.8 EAN30551.1 - 0.044 13.7 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain DUF389 PF04087.14 EAN30552.1 - 0.55 10.3 10.4 0.92 9.5 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF389) PPTA PF01239.22 EAN30553.1 - 0.00026 20.6 0.9 0.00045 19.9 0.3 1.8 2 0 0 2 2 2 1 Protein prenyltransferase alpha subunit repeat YrvL PF14184.6 EAN30553.1 - 0.015 15.4 0.1 0.017 15.2 0.1 1.1 1 0 0 1 1 1 0 Regulatory protein YrvL DUF1951 PF09188.10 EAN30554.1 - 0.076 13.0 1.6 0.12 12.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1951) SWIRM PF04433.17 EAN30555.1 - 2.2e-26 92.0 1.2 4.2e-26 91.1 0.2 2.1 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EAN30555.1 - 1.8e-08 34.2 4.7 4.4e-08 33.0 4.7 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EAN30555.1 - 7.5e-08 32.4 0.0 2.1e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAN30555.1 - 0.003 17.8 0.0 0.0095 16.2 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAN30555.1 - 0.0039 17.1 0.0 0.0039 17.1 0.0 3.0 3 0 0 3 3 3 1 Myb DNA-binding like GDI PF00996.18 EAN30556.1 - 7.2e-180 598.1 0.1 8.4e-180 597.9 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor SH3_14 PF18343.1 EAN30556.1 - 0.066 13.3 0.0 0.62 10.2 0.0 2.5 3 0 0 3 3 3 0 Dda helicase SH3 domain Ribosomal_S19e PF01090.19 EAN30557.1 - 2.4e-49 166.5 0.0 2.9e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L7Ae PF01248.26 EAN30558.1 - 1.3e-21 76.1 0.1 1.9e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 EAN30558.1 - 0.047 14.0 0.0 0.076 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding eIF-5_eIF-2B PF01873.17 EAN30559.1 - 1.8e-35 121.4 0.0 3.3e-35 120.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EAN30559.1 - 2e-07 31.0 0.0 6e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon GAGA_bind PF06217.12 EAN30559.1 - 0.013 15.8 5.6 0.018 15.4 5.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.17 EAN30559.1 - 0.032 14.4 1.0 0.063 13.4 1.2 1.5 2 0 0 2 2 2 0 DDHD domain Neur_chan_memb PF02932.16 EAN30559.1 - 0.13 12.3 5.0 0.19 11.8 5.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.13 EAN30559.1 - 0.18 10.7 4.6 0.32 9.9 4.6 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF913 PF06025.12 EAN30559.1 - 0.25 10.3 4.2 0.33 9.9 4.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sec62 PF03839.16 EAN30559.1 - 0.25 10.8 3.2 0.32 10.5 3.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2387 PF09526.10 EAN30559.1 - 0.27 11.4 0.1 0.27 11.4 0.1 2.4 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Zip PF02535.22 EAN30559.1 - 0.54 9.4 4.7 0.69 9.1 4.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Eapp_C PF10238.9 EAN30559.1 - 0.92 9.6 6.1 1.1 9.3 4.9 1.7 2 0 0 2 2 2 0 E2F-associated phosphoprotein POX PF07526.11 EAN30559.1 - 1.4 9.5 8.2 3.5 8.2 8.2 1.7 1 1 0 1 1 1 0 Associated with HOX RNA_polI_A34 PF08208.11 EAN30559.1 - 1.5 8.9 21.9 3 7.9 21.9 1.4 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Membralin PF09746.9 EAN30559.1 - 3.4 6.6 5.0 4.8 6.1 5.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein SLC12 PF03522.15 EAN30559.1 - 4.8 6.1 10.4 6.9 5.6 10.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 EAN30559.1 - 6 5.5 10.3 8.1 5.1 10.3 1.1 1 0 0 1 1 1 0 Presenilin Mago-bind PF09282.10 EAN30560.1 - 6.1e-12 45.2 5.2 1.1e-11 44.3 5.2 1.5 1 0 0 1 1 1 1 Mago binding LAP1C PF05609.12 EAN30560.1 - 0.027 13.6 0.7 0.036 13.1 0.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 EAN30560.1 - 0.2 10.4 2.3 0.32 9.7 2.3 1.3 1 0 0 1 1 1 0 Presenilin HRG PF16954.5 EAN30560.1 - 4.7 7.7 5.5 0.39 11.1 0.2 2.0 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Oxidored_q2 PF00420.24 EAN30561.1 - 0.13 11.9 0.1 0.13 11.9 0.1 3.1 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Spc7 PF08317.11 EAN30563.1 - 0.00038 19.4 86.0 0.056 12.3 23.8 4.5 2 2 2 4 4 4 4 Spc7 kinetochore protein ERM PF00769.19 EAN30563.1 - 0.0039 17.0 11.4 0.0039 17.0 11.4 3.8 1 1 2 3 3 3 1 Ezrin/radixin/moesin family Fez1 PF06818.15 EAN30563.1 - 0.0094 16.4 23.2 0.0094 16.4 23.2 4.3 1 1 5 6 6 6 2 Fez1 AAA_13 PF13166.6 EAN30563.1 - 0.042 12.5 68.4 0.019 13.7 27.6 3.3 1 1 2 3 3 3 0 AAA domain TPR_MLP1_2 PF07926.12 EAN30563.1 - 1.7 8.7 82.3 0.75 9.9 18.5 5.6 2 2 4 6 6 6 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 EAN30563.1 - 3.8 7.9 42.7 0.37 11.2 11.8 4.8 2 2 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) Asp4 PF16996.5 EAN30563.1 - 4.2 7.2 6.6 1.5 8.6 1.4 2.7 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 Exonuc_VII_L PF02601.15 EAN30563.1 - 5.4 6.5 76.3 26 4.2 16.5 4.3 1 1 2 3 3 3 0 Exonuclease VII, large subunit FAM184 PF15665.5 EAN30563.1 - 8 6.2 78.2 0.45 10.3 21.1 3.8 2 1 1 4 4 4 0 Family with sequence similarity 184, A and B Cpn60_TCP1 PF00118.24 EAN30564.1 - 1.6e-144 482.2 2.0 1.9e-144 482.0 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_lid_5 PF17865.1 EAN30564.1 - 0.095 12.8 2.9 0.1 12.7 0.3 2.3 3 0 0 3 3 3 0 Midasin AAA lid domain RF-1 PF00472.20 EAN30565.1 - 8.6e-08 32.1 0.8 1.4e-07 31.4 0.1 1.6 1 1 1 2 2 2 1 RF-1 domain SCIMP PF15050.6 EAN30566.1 - 0.5 10.8 2.4 0.64 10.5 0.3 2.1 2 0 0 2 2 2 0 SCIMP protein Forkhead_N PF08430.12 EAN30568.1 - 0.022 15.4 22.2 0.027 15.1 22.2 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region Sporozoite_P67 PF05642.11 EAN30568.1 - 1.7 6.7 11.3 1.9 6.5 11.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VEFS-Box PF09733.9 EAN30569.1 - 4.1 7.2 6.5 1.1 9.1 0.2 2.5 2 0 0 2 2 2 0 VEFS-Box of polycomb protein DAO PF01266.24 EAN30571.1 - 1.4e-40 140.0 0.0 2e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EAN30571.1 - 2e-38 131.1 0.0 3.4e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EAN30571.1 - 1.5e-08 34.2 0.6 1.3e-05 24.5 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 EAN30571.1 - 2.8e-05 23.6 0.0 0.00049 19.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EAN30571.1 - 0.00034 19.9 0.0 0.0013 18.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAN30571.1 - 0.00064 19.2 0.1 0.0088 15.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EAN30571.1 - 0.0016 17.6 0.7 0.047 12.8 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EAN30571.1 - 0.0023 17.2 0.1 0.049 12.9 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EAN30571.1 - 0.0089 16.2 0.2 0.018 15.2 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAN30571.1 - 0.039 13.0 0.2 0.092 11.8 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EAN30571.1 - 0.064 12.5 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1962 PF09227.10 EAN30571.1 - 0.17 12.3 1.7 0.32 11.4 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1962) LSM PF01423.22 EAN30573.1 - 1.3e-17 63.2 0.2 1.6e-17 62.9 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EAN30573.1 - 0.15 12.2 0.1 0.46 10.6 0.0 1.8 2 0 0 2 2 2 0 RimP C-terminal SH3 domain zf-C2H2_4 PF13894.6 EAN30574.1 - 2.1e-08 34.3 11.3 0.00045 20.8 1.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EAN30574.1 - 5.1e-07 29.8 11.3 0.0051 17.2 1.4 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type Actin_micro PF17003.5 EAN30574.1 - 0.00075 18.8 3.0 0.00075 18.8 3.0 1.5 1 1 1 2 2 2 1 Putative actin-like family zf-C2H2_aberr PF17017.5 EAN30574.1 - 0.002 18.3 3.1 0.002 18.3 3.1 2.2 1 1 1 2 2 2 1 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 EAN30574.1 - 0.0033 17.7 2.7 0.0089 16.3 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding UPF0515 PF15135.6 EAN30574.1 - 0.0073 15.7 2.7 0.0085 15.5 0.6 1.8 1 1 0 2 2 2 1 Uncharacterised protein UPF0515 Corona_NS8 PF12093.8 EAN30574.1 - 0.0076 16.8 0.1 0.01 16.4 0.1 1.2 1 0 0 1 1 1 1 Coronavirus NS8 protein zf-MYST PF17772.1 EAN30574.1 - 0.01 15.4 1.0 0.026 14.1 0.4 2.1 2 1 1 3 3 3 0 MYST family zinc finger domain zf-C2H2_9 PF16293.5 EAN30574.1 - 0.018 14.9 0.7 0.42 10.5 0.2 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 EAN30574.1 - 0.031 14.7 1.9 0.075 13.5 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.15 EAN30574.1 - 0.037 14.1 0.1 0.037 14.1 0.1 2.2 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.7 EAN30574.1 - 0.07 13.5 3.4 0.2 12.0 3.2 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 EAN30574.1 - 0.12 10.9 0.1 0.12 10.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-DBF PF07535.12 EAN30574.1 - 0.2 11.8 2.3 2 8.6 0.3 2.6 2 0 0 2 2 2 0 DBF zinc finger FOXP-CC PF16159.5 EAN30574.1 - 0.39 11.4 2.7 6 7.6 0.4 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 EAN30574.1 - 0.55 10.8 0.3 0.55 10.8 0.3 4.2 4 1 0 4 4 4 0 Zinc-finger double domain zf-Di19 PF05605.12 EAN30574.1 - 0.64 10.4 8.5 0.24 11.7 0.7 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding WD40 PF00400.32 EAN30575.1 - 2e-33 113.8 21.7 1.9e-07 31.6 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN30575.1 - 2.5e-10 40.5 3.0 0.084 13.2 0.3 4.7 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAN30575.1 - 1.2e-07 31.0 8.6 0.0024 16.9 4.5 3.6 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PhnA_Zn_Ribbon PF08274.12 EAN30575.1 - 0.037 14.0 0.2 0.23 11.5 0.0 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon MPC PF03650.13 EAN30576.1 - 2.5e-33 114.5 0.2 2.8e-33 114.3 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers zf-Tim10_DDP PF02953.15 EAN30577.1 - 5.6e-15 54.7 1.2 8.1e-15 54.2 1.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RRM_1 PF00076.22 EAN30578.1 - 0.00072 19.3 1.0 0.0055 16.5 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-cone PF03477.16 EAN30578.1 - 1.3 9.6 0.0 1.3 9.6 0.0 3.7 6 0 0 6 6 6 0 ATP cone domain FAINT PF04385.15 EAN30579.1 - 1.6e-17 63.3 19.7 4.1e-08 33.2 0.9 5.3 5 0 0 5 5 5 3 Domain of unknown function, DUF529 Hydrolase_4 PF12146.8 EAN30579.1 - 1e-13 51.1 0.0 3.8e-11 42.7 0.0 3.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EAN30579.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 EAN30579.1 - 0.041 13.4 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 EAN30579.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold TMEM154 PF15102.6 EAN30581.1 - 0.23 11.4 0.5 9.7 6.1 0.3 2.5 2 0 0 2 2 2 0 TMEM154 protein family Uso1_p115_C PF04871.13 EAN30583.1 - 5.3e-06 26.8 4.3 8.7e-06 26.1 4.3 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Trimer_CC PF08954.11 EAN30583.1 - 0.00011 21.7 3.0 0.0033 16.9 0.9 2.5 2 0 0 2 2 2 1 Trimerisation motif Rab5-bind PF09311.11 EAN30583.1 - 0.00037 20.0 2.2 0.0007 19.1 2.2 1.4 1 0 0 1 1 1 1 Rabaptin-like protein ADIP PF11559.8 EAN30583.1 - 0.00046 20.3 4.5 0.00085 19.4 4.5 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Sec34 PF04136.15 EAN30583.1 - 0.00058 19.8 3.8 0.00058 19.8 3.8 2.0 2 0 0 2 2 2 1 Sec34-like family ATG16 PF08614.11 EAN30583.1 - 0.00067 19.9 3.4 0.00067 19.9 3.4 1.9 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.11 EAN30583.1 - 0.001 18.0 2.4 0.0015 17.5 2.4 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.6 EAN30583.1 - 0.001 18.5 0.4 0.0019 17.6 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Spc7 PF08317.11 EAN30583.1 - 0.0011 17.9 2.8 0.0011 17.9 2.8 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 EAN30583.1 - 0.0014 18.9 2.0 0.0014 18.9 2.0 1.9 2 1 1 3 3 2 1 JNK_SAPK-associated protein-1 Mod_r PF07200.13 EAN30583.1 - 0.0015 18.7 3.3 0.0015 18.7 3.3 2.0 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 EAN30583.1 - 0.0019 18.7 5.3 0.0019 18.7 5.3 1.7 2 0 0 2 2 1 1 Apg6 coiled-coil region AIP3 PF03915.13 EAN30583.1 - 0.0035 16.5 0.8 0.0044 16.2 0.2 1.4 2 0 0 2 2 1 1 Actin interacting protein 3 TMF_DNA_bd PF12329.8 EAN30583.1 - 0.0054 16.7 11.5 2.8 8.0 0.8 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 EAN30583.1 - 0.0056 16.5 8.1 0.037 13.9 3.3 2.3 1 1 1 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor FAM184 PF15665.5 EAN30583.1 - 0.0056 16.5 5.7 0.014 15.2 1.1 2.1 2 0 0 2 2 2 1 Family with sequence similarity 184, A and B CENP-H PF05837.12 EAN30583.1 - 0.007 16.8 3.4 0.014 15.8 3.4 1.5 1 0 0 1 1 1 1 Centromere protein H (CENP-H) DUF2968 PF11180.8 EAN30583.1 - 0.0083 15.8 1.5 0.013 15.1 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Filament PF00038.21 EAN30583.1 - 0.0095 15.5 3.2 0.12 11.9 2.9 2.0 2 0 0 2 2 2 1 Intermediate filament protein DUF3450 PF11932.8 EAN30583.1 - 0.012 14.9 0.6 0.02 14.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc29 PF17082.5 EAN30583.1 - 0.018 14.9 1.8 0.33 10.8 2.0 2.2 1 1 0 1 1 1 0 Spindle Pole Component 29 Fib_alpha PF08702.10 EAN30583.1 - 0.019 15.2 5.7 0.11 12.6 4.1 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 EAN30583.1 - 0.019 15.2 6.3 0.072 13.3 4.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 EAN30583.1 - 0.019 15.2 2.3 0.3 11.4 0.1 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 EAN30583.1 - 0.02 15.0 2.1 0.02 15.0 2.1 1.6 2 0 0 2 2 1 0 Tropomyosin like KapB PF08810.10 EAN30583.1 - 0.02 15.0 1.6 1.1 9.5 0.0 2.6 2 1 1 3 3 2 0 Kinase associated protein B Exonuc_VII_L PF02601.15 EAN30583.1 - 0.029 13.9 0.3 0.029 13.9 0.3 1.5 2 0 0 2 2 1 0 Exonuclease VII, large subunit COG6 PF06419.11 EAN30583.1 - 0.03 12.6 5.8 0.04 12.2 4.4 1.7 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 MAP65_ASE1 PF03999.12 EAN30583.1 - 0.032 13.0 4.1 0.15 10.7 3.5 1.9 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) KLRAQ PF10205.9 EAN30583.1 - 0.032 14.5 4.9 0.06 13.6 4.9 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Prominin PF05478.11 EAN30583.1 - 0.046 11.7 4.2 0.013 13.5 1.6 1.4 2 0 0 2 2 2 0 Prominin FapA PF03961.13 EAN30583.1 - 0.05 12.2 0.6 0.069 11.7 0.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 EAN30583.1 - 0.06 13.1 7.4 0.073 12.9 4.0 2.5 2 1 1 3 3 2 0 Septum formation initiator UPF0242 PF06785.11 EAN30583.1 - 0.062 13.4 5.4 0.27 11.3 3.4 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4710 PF15828.5 EAN30583.1 - 0.082 13.0 1.1 0.15 12.2 0.6 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4710) SpecificRecomb PF10136.9 EAN30583.1 - 0.097 11.0 0.1 0.14 10.4 0.1 1.2 1 0 0 1 1 1 0 Site-specific recombinase zf-C4H2 PF10146.9 EAN30583.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.5 2 0 0 2 2 1 0 Zinc finger-containing protein Tho2 PF11262.8 EAN30583.1 - 0.1 11.8 2.3 0.1 11.8 0.8 1.7 2 0 0 2 2 1 0 Transcription factor/nuclear export subunit protein 2 IFT57 PF10498.9 EAN30583.1 - 0.1 11.5 4.3 0.13 11.2 2.4 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 WD40_alt PF14077.6 EAN30583.1 - 0.1 12.5 0.6 3.7 7.5 0.0 3.0 3 0 0 3 3 2 0 Alternative WD40 repeat motif OmpH PF03938.14 EAN30583.1 - 0.11 12.9 4.7 0.053 13.9 1.9 1.7 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) DUF4795 PF16043.5 EAN30583.1 - 0.11 12.1 2.7 0.21 11.2 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_GP20 PF06810.11 EAN30583.1 - 0.11 12.3 7.5 0.35 10.6 4.7 2.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF1192 PF06698.11 EAN30583.1 - 0.11 12.6 0.6 0.42 10.7 0.0 2.2 3 0 0 3 3 1 0 Protein of unknown function (DUF1192) CENP-F_leu_zip PF10473.9 EAN30583.1 - 0.11 12.5 6.6 0.22 11.5 6.6 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EAN30583.1 - 0.12 12.4 7.4 0.15 12.1 4.0 2.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4763 PF15960.5 EAN30583.1 - 0.13 11.6 6.5 0.51 9.6 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) P4Ha_N PF08336.11 EAN30583.1 - 0.14 12.2 3.1 0.16 12.0 0.6 2.0 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF1664 PF07889.12 EAN30583.1 - 0.14 12.2 1.8 0.19 11.8 1.1 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EAN30583.1 - 0.15 12.6 4.9 0.21 12.1 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 FliJ PF02050.16 EAN30583.1 - 0.17 12.1 5.3 4.3 7.6 3.2 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein PAH PF02671.21 EAN30583.1 - 0.17 12.0 3.8 0.21 11.7 0.7 2.6 3 0 0 3 3 2 0 Paired amphipathic helix repeat CEP63 PF17045.5 EAN30583.1 - 0.19 11.6 5.8 0.26 11.1 4.0 1.8 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa DUF4201 PF13870.6 EAN30583.1 - 0.19 11.4 9.9 0.34 10.6 5.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Seryl_tRNA_N PF02403.22 EAN30583.1 - 0.2 11.9 5.2 0.26 11.5 4.0 1.7 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.15 EAN30583.1 - 0.2 12.1 5.9 0.59 10.6 6.0 1.7 1 1 0 1 1 1 0 Fez1 DUF3552 PF12072.8 EAN30583.1 - 0.22 10.9 7.4 2.3 7.6 6.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF5082 PF16888.5 EAN30583.1 - 0.23 11.7 3.8 1.1 9.5 3.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) BLOC1_2 PF10046.9 EAN30583.1 - 0.24 11.7 7.5 0.88 9.9 5.5 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lectin_N PF03954.14 EAN30583.1 - 0.27 11.0 4.6 0.28 10.9 2.3 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain TSNAXIP1_N PF15739.5 EAN30583.1 - 0.29 11.5 5.9 11 6.5 2.6 2.4 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF3510 PF12022.8 EAN30583.1 - 0.31 11.4 3.0 2.8 8.3 1.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) V_ATPase_I PF01496.19 EAN30583.1 - 0.33 8.8 2.7 0.42 8.5 2.2 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family JIP_LZII PF16471.5 EAN30583.1 - 0.35 11.1 5.2 8.8 6.6 0.1 2.8 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II SlyX PF04102.12 EAN30583.1 - 0.42 11.3 3.0 3.6 8.3 0.4 2.6 2 1 1 3 3 2 0 SlyX Mating_N PF12731.7 EAN30583.1 - 0.45 10.6 2.9 12 6.1 0.1 2.9 3 0 0 3 3 3 0 Mating-type protein beta 1 FadA PF09403.10 EAN30583.1 - 0.47 11.0 7.5 0.33 11.4 5.2 1.9 2 1 0 2 2 1 0 Adhesion protein FadA GAS PF13851.6 EAN30583.1 - 0.61 9.4 10.5 1.9 7.8 8.7 2.2 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 EAN30583.1 - 0.62 10.6 8.4 3.3 8.2 8.3 2.1 1 1 1 2 2 2 0 Cell division protein ZapB EzrA PF06160.12 EAN30583.1 - 0.65 8.1 7.5 0.13 10.4 3.7 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Macoilin PF09726.9 EAN30583.1 - 0.7 8.4 5.7 1.6 7.2 5.2 1.7 1 1 1 2 2 2 0 Macoilin family FtsX_ECD PF18075.1 EAN30583.1 - 0.75 10.5 3.1 35 5.1 0.1 2.9 2 1 1 3 3 3 0 FtsX extracellular domain DUF948 PF06103.11 EAN30583.1 - 1 9.7 2.5 2.9 8.2 1.6 2.1 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 EAN30583.1 - 1.2 9.5 9.0 5.1 7.4 5.3 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein FAM76 PF16046.5 EAN30583.1 - 1.5 8.1 3.9 1.2 8.4 2.3 1.5 2 0 0 2 2 2 0 FAM76 protein BST2 PF16716.5 EAN30583.1 - 1.6 9.4 6.8 11 6.7 3.2 2.5 2 1 1 3 3 2 0 Bone marrow stromal antigen 2 YabA PF06156.13 EAN30583.1 - 2.6 8.8 7.5 2.8 8.6 5.4 2.1 2 1 0 2 2 1 0 Initiation control protein YabA Spc24 PF08286.11 EAN30583.1 - 2.6 8.3 8.9 49 4.2 8.9 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 BRE1 PF08647.11 EAN30583.1 - 2.9 8.0 9.7 1.2 9.2 6.9 1.8 2 1 0 2 2 1 0 BRE1 E3 ubiquitin ligase XhlA PF10779.9 EAN30583.1 - 2.9 8.2 4.7 4.3 7.6 3.9 1.8 2 0 0 2 2 1 0 Haemolysin XhlA Cor1 PF04803.12 EAN30583.1 - 6.3 7.0 10.4 9.6 6.4 0.3 2.5 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region DivIVA PF05103.13 EAN30583.1 - 7.4 6.7 8.7 3.2 7.9 2.2 2.7 2 1 1 3 3 3 0 DivIVA protein CH PF00307.31 EAN30584.1 - 2.7e-09 37.2 2.5 3.2e-09 36.9 0.5 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain EB1 PF03271.17 EAN30584.1 - 1.9e-08 34.4 0.2 1.9e-08 34.4 0.2 2.6 2 0 0 2 2 2 1 EB1-like C-terminal motif FPP PF05911.11 EAN30584.1 - 0.004 15.4 2.8 0.004 15.4 2.8 1.6 1 1 0 2 2 2 1 Filament-like plant protein, long coiled-coil DnaB PF00772.21 EAN30584.1 - 0.0069 16.4 0.2 0.28 11.3 0.0 2.6 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain CH_2 PF06294.11 EAN30584.1 - 0.93 9.7 8.8 0.058 13.5 0.9 2.8 3 0 0 3 3 3 0 CH-like domain in sperm protein DUF5339 PF17274.2 EAN30584.1 - 2.3 9.1 6.8 1 10.3 2.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Ribosomal_L30 PF00327.20 EAN30585.1 - 7.2e-18 64.2 2.4 2.4e-17 62.6 2.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 EAN30585.1 - 1.5e-14 54.0 16.1 2.6e-14 53.2 16.1 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DNA_pol_B_exo1 PF03104.19 EAN30585.1 - 0.09 11.9 0.3 0.11 11.6 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain Radial_spoke_3 PF06098.11 EAN30585.1 - 1.2 8.4 7.9 1.6 8.0 7.9 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 Ribosom_S12_S23 PF00164.25 EAN30586.1 - 2.5e-49 165.6 0.4 3.4e-49 165.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 RNA_pol_Rpb2_6 PF00562.28 EAN30587.1 - 1.8e-125 419.0 0.3 2.5e-125 418.6 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EAN30587.1 - 2.1e-38 131.9 0.0 6.9e-22 78.0 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EAN30587.1 - 3.5e-30 104.2 0.1 1.1e-29 102.7 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EAN30587.1 - 2.9e-22 78.7 1.1 6e-22 77.7 1.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 EAN30587.1 - 1e-20 74.2 0.3 2.1e-20 73.2 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 EAN30587.1 - 1.5e-17 63.5 0.0 3e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EAN30587.1 - 5.6e-08 33.2 0.2 2.1e-07 31.4 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Sec63 PF02889.16 EAN30588.1 - 5.1e-127 422.4 13.3 2.6e-81 272.6 0.1 3.2 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 EAN30588.1 - 5.8e-36 123.9 7.8 9.9e-25 87.3 0.2 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EAN30588.1 - 6e-35 119.8 4.7 2.9e-34 117.6 4.7 2.4 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EAN30588.1 - 2.1e-14 53.9 1.5 5.1e-10 39.6 0.1 3.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAN30588.1 - 3.4e-05 24.1 14.8 4.9e-05 23.6 0.0 6.4 5 3 0 5 5 5 1 Helicase conserved C-terminal domain T2SSE PF00437.20 EAN30588.1 - 0.058 12.4 0.0 0.21 10.6 0.0 1.9 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 EAN30588.1 - 0.059 13.2 0.1 0.059 13.2 0.1 3.3 2 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EAN30588.1 - 0.07 13.5 0.1 0.34 11.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAN30588.1 - 0.28 11.4 2.1 48 4.2 0.0 3.9 4 0 0 4 4 4 0 AAA domain Oxidored_q2 PF00420.24 EAN30589.1 - 9.9 5.8 12.6 0.2 11.3 0.2 3.4 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L zf-HC5HC2H PF13771.6 EAN30591.1 - 6.6e-10 39.1 14.1 1.3e-08 35.0 5.8 2.6 2 0 0 2 2 2 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EAN30591.1 - 9.5e-08 32.2 5.9 9.5e-08 32.2 5.9 2.5 2 0 0 2 2 2 2 PHD-zinc-finger like domain PHD PF00628.29 EAN30591.1 - 3.6e-06 26.8 23.6 0.00011 22.0 11.9 3.3 2 1 1 3 3 3 2 PHD-finger PyrI_C PF02748.15 EAN30591.1 - 4.9 7.1 12.8 6.5 6.8 2.2 3.7 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FANCL_C PF11793.8 EAN30591.1 - 7.7 6.8 17.9 7.5 6.8 5.0 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 EAN30592.1 - 6.3e-09 36.0 7.8 6.3e-09 36.0 7.8 4.9 6 0 0 6 6 6 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EAN30592.1 - 6.9e-06 26.2 8.9 6.9e-06 26.2 8.9 5.1 4 2 2 6 6 6 1 PHD-like zinc-binding domain Rhomboid PF01694.22 EAN30594.1 - 1.3e-18 67.4 6.2 5.5e-11 42.7 2.0 2.3 2 0 0 2 2 2 2 Rhomboid family Ribosomal_L15e PF00827.17 EAN30596.1 - 5.2e-91 303.6 9.5 6e-91 303.4 9.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 Clat_adaptor_s PF01217.20 EAN30597.1 - 2.6e-10 40.4 4.6 0.00011 22.2 0.4 2.1 1 1 1 2 2 2 2 Clathrin adaptor complex small chain AAA_18 PF13238.6 EAN30597.1 - 0.14 12.7 0.8 8.7 6.9 0.8 2.2 1 1 0 1 1 1 0 AAA domain AP2 PF00847.20 EAN30598.1 - 6.8e-18 64.6 2.4 6.8e-18 64.6 2.4 1.7 2 0 0 2 2 2 1 AP2 domain DAO PF01266.24 EAN30599.1 - 0.0001 22.0 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAN30599.1 - 0.00021 20.7 0.1 0.0012 18.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF1837 PF08878.11 EAN30599.1 - 0.045 13.5 0.0 5.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1837) DUF1664 PF07889.12 EAN30601.1 - 0.084 12.9 4.7 0.22 11.5 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2312 PF10073.9 EAN30601.1 - 1.9 8.2 5.0 1.3 8.7 0.9 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) SUIM_assoc PF16619.5 EAN30602.1 - 0.036 14.1 0.1 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4294 PF14127.6 EAN30602.1 - 0.096 12.6 0.2 0.14 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) DUF1835 PF08874.10 EAN30602.1 - 0.16 12.2 0.1 0.24 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) SWIB PF02201.18 EAN30603.1 - 1.8e-07 30.9 0.2 9.4e-05 22.2 0.0 2.7 2 0 0 2 2 2 2 SWIB/MDM2 domain Y_Y_Y PF07495.13 EAN30603.1 - 0.00043 20.2 0.5 0.00043 20.2 0.5 2.1 2 0 0 2 2 2 1 Y_Y_Y domain DUF4539 PF15072.6 EAN30605.1 - 3.9e-09 36.4 0.3 6.5e-09 35.7 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Zip PF02535.22 EAN30606.1 - 8.7e-22 77.8 9.4 3.2e-21 75.9 9.4 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter NADH-G_4Fe-4S_3 PF10588.9 EAN30606.1 - 1.6 8.3 7.4 11 5.7 2.4 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NUDIX PF00293.28 EAN30607.1 - 1.5e-08 34.8 0.0 2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Dor1 PF04124.12 EAN30609.1 - 0.032 12.9 7.3 0.09 11.4 7.3 1.7 1 1 0 1 1 1 0 Dor1-like family HALZ PF02183.18 EAN30609.1 - 2.4 8.4 8.0 1.4 9.2 2.5 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper CPBP PF02517.16 EAN30611.1 - 2.4e-13 50.2 3.1 2.4e-13 50.2 3.1 2.0 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DEAD_2 PF06733.15 EAN30612.1 - 0.28 10.8 4.8 0.21 11.2 0.9 2.2 2 0 0 2 2 2 0 DEAD_2 CUE PF02845.16 EAN30613.1 - 0.046 13.4 1.1 0.082 12.6 1.1 1.4 1 0 0 1 1 1 0 CUE domain Lyase_1 PF00206.20 EAN30614.1 - 9.9e-37 127.0 0.0 1.4e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 EAN30614.1 - 1.5e-30 105.6 0.0 3e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Ras PF00071.22 EAN30616.1 - 8.3e-58 194.6 5.5 1.6e-57 193.6 5.5 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EAN30616.1 - 1.6e-31 109.0 0.6 3.9e-31 107.8 0.6 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAN30616.1 - 2.2e-14 53.3 0.8 3.2e-14 52.8 0.8 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAN30616.1 - 1.9e-05 24.3 3.3 0.00014 21.4 3.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAN30616.1 - 3.6e-05 23.2 1.4 5e-05 22.8 1.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAN30616.1 - 0.00062 19.8 0.5 0.0014 18.7 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAN30616.1 - 0.0017 18.2 3.6 0.85 9.5 0.7 2.3 2 1 0 2 2 2 2 RsgA GTPase Septin PF00735.18 EAN30616.1 - 0.0021 17.4 0.3 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Septin AAA_22 PF13401.6 EAN30616.1 - 0.0032 17.8 0.3 0.028 14.7 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 EAN30616.1 - 0.0033 17.2 2.8 0.0084 15.9 2.8 1.9 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 EAN30616.1 - 0.0049 16.7 0.3 0.021 14.6 0.1 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 EAN30616.1 - 0.0064 15.9 2.2 0.042 13.3 2.1 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAN30616.1 - 0.035 14.5 0.1 0.061 13.7 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EAN30616.1 - 0.083 12.9 0.0 0.33 11.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EAN30616.1 - 0.089 12.6 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 EAN30616.1 - 0.17 11.5 2.2 0.82 9.2 0.2 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CBS PF00571.28 EAN30617.1 - 1.4e-06 28.6 0.0 0.014 15.8 0.0 4.3 4 0 0 4 4 4 2 CBS domain Nup_retrotrp_bd PF10599.9 EAN30618.1 - 0.015 15.9 0.2 0.025 15.2 0.2 1.3 1 0 0 1 1 1 0 Retro-transposon transporting motif Isy1 PF06246.12 EAN30619.1 - 0.025 14.1 0.3 0.039 13.5 0.3 1.3 1 0 0 1 1 1 0 Isy1-like splicing family Ipi1_N PF12333.8 EAN30619.1 - 0.026 15.1 0.3 0.054 14.1 0.3 1.5 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Mersacidin PF16934.5 EAN30619.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) DASH_Dad3 PF08656.10 EAN30619.1 - 0.35 11.0 5.7 0.17 12.0 1.6 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 SIT PF15330.6 EAN30621.1 - 0.14 12.6 0.8 0.52 10.8 0.8 1.9 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT NUC153 PF08159.12 EAN30623.1 - 7.8e-08 32.0 1.1 7.8e-08 32.0 1.1 3.0 4 0 0 4 4 4 1 NUC153 domain Proteasom_PSMB PF10508.9 EAN30625.1 - 0.00018 20.2 1.8 0.0055 15.3 0.4 2.4 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit DUF4070 PF13282.6 EAN30625.1 - 0.0042 17.2 0.1 0.018 15.2 0.2 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4070) Patatin PF01734.22 EAN30627.1 - 1.1e-23 84.5 0.0 2.5e-23 83.3 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase SYCP2_ARLD PF18581.1 EAN30627.1 - 0.49 10.4 6.3 1.1 9.3 2.7 2.8 2 1 0 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain eIF-3_zeta PF05091.12 EAN30628.1 - 3.4e-163 544.4 4.5 4e-163 544.1 4.5 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hist_deacetyl PF00850.19 EAN30629.1 - 5.4e-103 344.7 0.0 9e-103 343.9 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain IPK PF03770.16 EAN30629.1 - 4.1e-39 134.5 0.5 4.1e-39 134.5 0.5 2.1 2 0 0 2 2 2 1 Inositol polyphosphate kinase UPF0137 PF03677.13 EAN30629.1 - 0.033 14.0 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0137) POP1 PF06978.11 EAN30630.1 - 9.3e-34 117.2 27.6 7.5e-19 68.5 2.8 2.9 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EAN30630.1 - 2.4e-18 66.3 0.0 8.2e-18 64.5 0.0 2.0 1 0 0 1 1 1 1 POPLD (NUC188) domain DEAD PF00270.29 EAN30631.1 - 6.2e-29 101.0 1.6 1.2e-28 100.1 0.2 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN30631.1 - 6.1e-15 55.5 4.4 3.7e-14 53.0 0.1 3.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN30631.1 - 0.00051 20.1 0.2 0.00051 20.1 0.2 3.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EAN30631.1 - 0.04 13.0 0.1 0.11 11.6 0.1 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoLip_ATPase_N PF16209.5 EAN30631.1 - 0.26 11.0 3.6 11 5.8 0.1 3.7 3 0 0 3 3 3 0 Phospholipid-translocating ATPase N-terminal Snf7 PF03357.21 EAN30632.1 - 6.5e-13 48.6 5.4 8.5e-13 48.3 5.4 1.2 1 0 0 1 1 1 1 Snf7 Spatacsin_C PF14649.6 EAN30632.1 - 0.016 14.3 0.8 0.026 13.6 0.6 1.4 1 1 0 1 1 1 0 Spatacsin C-terminus DUF3939 PF13075.6 EAN30632.1 - 0.14 12.2 3.2 0.43 10.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3939) SPC25 PF06703.11 EAN30633.1 - 1.7e-07 31.2 4.0 1.9e-07 31.0 4.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) dCMP_cyt_deam_1 PF00383.23 EAN30634.1 - 6.1e-17 61.3 1.0 7.8e-17 61.0 1.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EAN30634.1 - 3.2e-13 49.6 2.9 2e-12 47.0 2.9 1.8 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EAN30634.1 - 0.01 15.9 0.7 0.017 15.2 0.7 1.4 1 1 0 1 1 1 0 Bd3614-like deaminase SCAB_CC PF16712.5 EAN30634.1 - 0.051 13.4 0.7 0.066 13.0 0.7 1.1 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Kinase-PPPase PF03618.14 EAN30634.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Kinase/pyrophosphorylase Clathrin_lg_ch PF01086.17 EAN30634.1 - 0.17 12.0 0.1 0.22 11.6 0.1 1.1 1 0 0 1 1 1 0 Clathrin light chain DUF3144 PF11342.8 EAN30635.1 - 0.11 12.8 0.0 0.48 10.8 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) GTP1_OBG PF01018.22 EAN30636.1 - 1.5e-27 96.1 0.8 1.9e-27 95.8 0.8 1.1 1 0 0 1 1 1 1 GTP1/OBG OHA PF14418.6 EAN30637.1 - 1.3e-25 89.0 0.0 2.9e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 OST-HTH Associated domain OST-HTH PF12872.7 EAN30637.1 - 0.00023 20.9 0.1 0.00056 19.7 0.1 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain MACPF PF01823.19 EAN30639.1 - 2.2e-33 116.1 16.9 3.7e-33 115.4 16.9 1.3 1 0 0 1 1 1 1 MAC/Perforin domain MACPF PF01823.19 EAN30640.1 - 3.7e-48 164.4 9.0 5.5e-48 163.8 9.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain MACPF PF01823.19 EAN30642.1 - 1e-43 149.9 7.2 1.4e-43 149.5 7.2 1.2 1 0 0 1 1 1 1 MAC/Perforin domain UbiA PF01040.18 EAN30643.1 - 1.2e-44 152.6 8.7 1.5e-44 152.2 8.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2062 PF09835.9 EAN30643.1 - 0.0097 15.8 0.6 0.021 14.7 0.6 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) Drc1-Sld2 PF11719.8 EAN30644.1 - 0.0065 16.1 0.0 0.0083 15.7 0.0 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein Peptidase_S24 PF00717.23 EAN30645.1 - 1.1e-12 47.7 0.1 1.8e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like CPW_WPC PF09717.10 EAN30646.1 - 3.9e-19 69.4 42.7 5.3e-05 24.1 10.2 7.3 4 2 1 6 6 6 6 Plasmodium falciparum domain of unknown function (CPW_WPC) Gag_MA PF01140.19 EAN30646.1 - 1.3 8.8 4.6 0.95 9.2 0.3 2.6 2 1 0 2 2 2 0 Matrix protein (MA), p15 Porin_1 PF00267.21 EAN30649.1 - 0.022 14.2 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 Gram-negative porin Proteasome PF00227.26 EAN30650.1 - 1.4e-54 184.5 0.0 2.2e-54 183.8 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 EAN30650.1 - 9.4e-10 38.0 0.8 1.6e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature MACPF PF01823.19 EAN30651.1 - 5.8e-25 88.6 0.5 1.1e-24 87.8 0.5 1.4 1 0 0 1 1 1 1 MAC/Perforin domain Sec34 PF04136.15 EAN30655.1 - 0.024 14.5 1.0 0.026 14.4 1.0 1.1 1 0 0 1 1 1 0 Sec34-like family EbsA PF17255.2 EAN30656.1 - 0.048 14.0 0.4 0.075 13.4 0.4 1.3 1 0 0 1 1 1 0 EbsA-like protein GTP_EFTU PF00009.27 EAN30657.1 - 4.3e-55 186.3 0.0 7.6e-55 185.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EAN30657.1 - 2.9e-31 107.8 0.0 7.8e-31 106.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EAN30657.1 - 7.5e-31 106.1 0.4 2.2e-30 104.6 0.1 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 EAN30657.1 - 8.5e-26 89.8 0.5 1.9e-25 88.7 0.5 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EAN30657.1 - 1.9e-07 31.4 0.4 6.5e-07 29.6 0.4 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EAN30657.1 - 2.3e-05 24.2 0.0 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EAN30657.1 - 0.018 15.2 1.5 0.025 14.6 0.1 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase DnaA_N PF11638.8 EAN30657.1 - 0.038 13.7 0.1 10 6.0 0.0 2.7 2 0 0 2 2 2 0 DnaA N-terminal domain Vezatin PF12632.7 EAN30657.1 - 0.044 13.1 0.6 0.084 12.2 0.6 1.4 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes DUF1754 PF08555.10 EAN30659.1 - 1e-15 58.3 2.5 1e-15 58.3 2.5 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Golgin_A5 PF09787.9 EAN30659.1 - 0.0067 15.9 4.5 0.0086 15.6 4.5 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 TCTP PF00838.17 EAN30659.1 - 0.0071 16.7 4.3 0.009 16.4 4.3 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein Fez1 PF06818.15 EAN30659.1 - 0.031 14.7 3.7 0.037 14.5 3.7 1.1 1 0 0 1 1 1 0 Fez1 DUF2205 PF10224.9 EAN30659.1 - 0.1 12.6 4.3 2.2 8.4 0.4 2.3 1 1 1 2 2 2 0 Short coiled-coil protein GrpE PF01025.19 EAN30659.1 - 0.11 12.1 6.1 0.047 13.3 3.9 1.4 2 0 0 2 2 2 0 GrpE TMPIT PF07851.13 EAN30659.1 - 0.27 10.4 3.2 0.36 10.0 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein KMP11 PF03037.16 EAN30659.1 - 0.35 11.7 6.1 0.16 12.7 3.6 1.8 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 DUF1604 PF07713.13 EAN30660.1 - 8.3e-10 38.4 0.3 3e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) DUF241 PF03087.14 EAN30660.1 - 0.046 13.6 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Sin_N PF04801.13 EAN30660.1 - 0.053 12.7 0.1 0.054 12.7 0.1 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region Ribosomal_S8e PF01201.22 EAN30662.1 - 1.1e-47 161.6 4.7 1.1e-47 161.6 4.7 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e FAINT PF04385.15 EAN30663.1 - 2.9e-25 88.1 34.1 1.7e-11 44.0 4.5 5.6 5 0 0 5 5 5 5 Domain of unknown function, DUF529 Sld5 PF05916.11 EAN30664.1 - 2e-19 70.0 2.8 2.3e-19 69.9 0.2 2.4 3 0 0 3 3 3 1 GINS complex protein TRAP_alpha PF03896.16 EAN30664.1 - 0.038 13.2 0.9 0.065 12.4 0.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SAP18 PF06487.12 EAN30665.1 - 2.7e-07 30.9 1.5 2.7e-07 30.9 1.5 2.8 2 2 0 2 2 2 1 Sin3 associated polypeptide p18 (SAP18) YscJ_FliF_C PF08345.11 EAN30665.1 - 0.0021 18.4 2.5 0.0021 18.4 2.5 2.9 2 1 0 2 2 2 1 Flagellar M-ring protein C-terminal AP2 PF00847.20 EAN30666.1 - 0.0099 16.1 0.2 0.019 15.2 0.2 1.4 1 0 0 1 1 1 1 AP2 domain NOG1_N PF17835.1 EAN30666.1 - 0.049 13.6 0.1 0.089 12.8 0.1 1.5 1 0 0 1 1 1 0 NOG1 N-terminal helical domain NIF PF03031.18 EAN30667.1 - 2e-15 56.9 3.4 2e-15 56.9 3.4 2.6 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase Zip PF02535.22 EAN30667.1 - 1.9 7.6 7.0 4 6.5 7.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2981 PF11200.8 EAN30667.1 - 6.3 6.4 12.6 15 5.2 12.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Spt5-NGN PF03439.13 EAN30669.1 - 4.5e-22 77.8 0.0 9.2e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 EAN30669.1 - 8.2e-22 76.4 29.0 8.8e-06 25.5 0.0 8.5 8 0 0 8 8 8 7 KOW motif Myosin_N PF02736.19 EAN30669.1 - 0.0014 18.4 16.3 0.14 12.1 3.7 4.4 4 0 0 4 4 4 2 Myosin N-terminal SH3-like domain Spt5_N PF11942.8 EAN30669.1 - 0.0076 17.2 5.4 0.18 12.8 1.8 2.6 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal ProQ_C PF17516.2 EAN30669.1 - 0.081 12.4 2.7 6.4 6.3 0.2 3.3 3 0 0 3 3 3 0 ProQ C-terminal domain eIF2_C PF09173.11 EAN30669.1 - 0.13 12.5 1.1 6.3 7.1 0.1 3.4 3 0 0 3 3 3 0 Initiation factor eIF2 gamma, C terminal YajC PF02699.15 EAN30669.1 - 1.2 9.0 15.5 2.9 7.8 0.9 5.6 4 1 1 5 5 5 0 Preprotein translocase subunit SH3_15 PF18346.1 EAN30669.1 - 2.4 8.5 7.3 19 5.6 0.1 4.1 3 2 0 3 3 3 0 Mind bomb SH3 repeat domain HlyD PF00529.20 EAN30669.1 - 6.2 6.8 5.7 28 4.7 0.0 3.6 2 1 1 3 3 3 0 HlyD membrane-fusion protein of T1SS FAINT PF04385.15 EAN30670.1 - 7.2e-10 38.8 11.1 0.0014 18.6 0.2 4.5 4 1 0 4 4 4 3 Domain of unknown function, DUF529 ID PF18543.1 EAN30670.1 - 0.039 14.0 1.7 0.078 13.0 0.8 1.9 2 0 0 2 2 2 0 Intracellular delivery domain DEAD PF00270.29 EAN30671.1 - 2.4e-45 154.4 0.0 1.8e-44 151.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN30671.1 - 1.6e-29 102.5 0.1 1.2e-28 99.7 0.1 2.2 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN30671.1 - 0.0005 20.1 0.0 0.0014 18.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAN30671.1 - 0.0023 17.2 0.0 0.0035 16.6 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Keratin_2_head PF16208.5 EAN30671.1 - 0.16 12.1 9.6 0.32 11.1 9.6 1.4 1 0 0 1 1 1 0 Keratin type II head Polyketide_cyc PF03364.20 EAN30672.1 - 2.3e-13 50.5 0.0 2.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PhoU PF01895.19 EAN30675.1 - 5.1 7.6 9.5 10 6.6 5.4 3.2 2 1 0 2 2 2 0 PhoU domain FAINT PF04385.15 EAN30676.1 - 0.00016 21.7 14.1 0.048 13.7 0.4 3.5 3 0 0 3 3 3 2 Domain of unknown function, DUF529 DUF971 PF06155.12 EAN30676.1 - 0.0054 17.4 0.2 1.3 9.7 0.1 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF971) Laminin_N PF00055.17 EAN30676.1 - 0.027 14.1 2.1 3.2 7.3 0.1 2.4 1 1 1 2 2 2 0 Laminin N-terminal (Domain VI) BCNT PF07572.12 EAN30677.1 - 1.7e-11 44.0 0.7 1.7e-11 44.0 0.7 2.5 2 0 0 2 2 2 1 Bucentaur or craniofacial development COX17 PF05051.13 EAN30678.1 - 8.8e-18 64.4 10.1 8.8e-18 64.4 10.1 1.5 1 1 1 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) DUF3585 PF12130.8 EAN30681.1 - 0.048 13.8 3.6 2.6 8.2 0.8 2.5 2 0 0 2 2 2 0 Bivalent Mical/EHBP Rab binding domain ThiF PF00899.21 EAN30682.1 - 7.7e-08 32.0 0.0 9.3e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family Pkinase PF00069.25 EAN30683.1 - 7.6e-54 182.8 0.1 3.7e-53 180.6 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN30683.1 - 4.7e-27 94.9 0.0 4.1e-20 72.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 EAN30683.1 - 0.001 18.8 0.1 0.3 10.7 0.0 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EAN30683.1 - 0.0017 18.0 0.6 0.13 11.9 0.1 2.4 1 1 0 2 2 2 1 RIO1 family APH PF01636.23 EAN30683.1 - 0.0022 18.0 0.0 0.15 11.9 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAN30683.1 - 0.0027 16.5 0.1 0.0049 15.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAN30683.1 - 0.0059 16.0 0.3 0.0096 15.3 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 EAN30684.1 - 0.04 14.4 0.0 0.049 14.1 0.0 1.2 1 0 0 1 1 1 0 PH domain LURAP PF14854.6 EAN30685.1 - 0.043 13.8 0.3 0.053 13.5 0.3 1.1 1 0 0 1 1 1 0 Leucine rich adaptor protein CBFD_NFYB_HMF PF00808.23 EAN30686.1 - 1.3e-21 76.6 0.3 2.7e-21 75.6 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAN30686.1 - 0.0051 17.2 0.1 0.0051 17.2 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF1033 PF06279.11 EAN30686.1 - 0.021 15.0 0.1 0.021 15.0 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) CENP-T_C PF15511.6 EAN30686.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EAN30686.1 - 0.03 14.3 0.1 0.086 12.9 0.1 1.8 1 1 1 2 2 2 0 Bromodomain associated TFIID_20kDa PF03847.13 EAN30686.1 - 0.096 13.2 0.1 0.37 11.3 0.1 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Peptidase_C13 PF01650.18 EAN30687.1 - 3.8e-13 49.5 1.2 6.6e-13 48.8 1.2 1.4 1 0 0 1 1 1 1 Peptidase C13 family ParA PF10609.9 EAN30689.1 - 1.1e-60 205.1 0.2 8.3e-60 202.3 0.2 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EAN30689.1 - 8.8e-10 38.7 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EAN30689.1 - 6.7e-09 35.9 0.7 1.5e-08 34.8 0.7 1.7 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 EAN30689.1 - 1.9e-07 30.7 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EAN30689.1 - 5.4e-05 22.5 0.9 0.00034 19.9 0.0 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EAN30689.1 - 0.016 14.7 0.0 0.079 12.4 0.0 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ DUF4305 PF14146.6 EAN30689.1 - 0.02 15.1 0.2 0.039 14.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4305) VirC1 PF07015.11 EAN30689.1 - 0.025 13.9 0.1 0.05 12.9 0.1 1.5 1 0 0 1 1 1 0 VirC1 protein AAA_25 PF13481.6 EAN30689.1 - 0.077 12.6 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 AAA domain Dermcidin PF15291.6 EAN30690.1 - 0.06 13.9 1.1 0.14 12.8 1.1 1.5 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide UPF0242 PF06785.11 EAN30690.1 - 0.066 13.3 4.6 0.12 12.5 4.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Uds1 PF15456.6 EAN30690.1 - 0.18 12.0 5.3 0.33 11.1 5.3 1.3 1 0 0 1 1 1 0 Up-regulated During Septation CcmH PF03918.14 EAN30690.1 - 0.2 10.9 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein EMC3_TMCO1 PF01956.16 EAN30690.1 - 0.21 11.3 0.6 0.38 10.5 0.6 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Spindle_Spc25 PF08234.12 EAN30692.1 - 6.1e-10 39.2 0.0 2.5e-09 37.2 0.0 2.0 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 SYCE1 PF15233.6 EAN30692.1 - 0.0098 16.0 2.9 0.2 11.7 0.0 2.2 2 0 0 2 2 2 1 Synaptonemal complex central element protein 1 HOOK PF05622.12 EAN30692.1 - 0.014 13.6 5.1 0.016 13.4 5.1 1.0 1 0 0 1 1 1 0 HOOK protein DASH_Duo1 PF08651.10 EAN30692.1 - 0.015 15.1 3.8 0.015 15.1 3.8 1.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF4200 PF13863.6 EAN30692.1 - 0.03 14.7 2.0 0.047 14.1 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) NolX PF05819.11 EAN30692.1 - 0.084 12.2 3.3 0.11 11.8 3.3 1.1 1 0 0 1 1 1 0 NolX protein UPF0449 PF15136.6 EAN30692.1 - 0.084 13.4 4.4 1 9.9 1.0 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DHR10 PF18595.1 EAN30692.1 - 0.11 12.6 1.7 0.97 9.5 0.1 2.1 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Atg14 PF10186.9 EAN30692.1 - 0.15 11.1 6.5 0.21 10.7 6.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 EAN30692.1 - 2.1 8.4 6.1 10 6.2 5.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SecY PF00344.20 EAN30693.1 - 8.2e-70 235.5 8.0 8.2e-70 235.5 8.0 1.3 2 0 0 2 2 2 1 SecY translocase Plug_translocon PF10559.9 EAN30693.1 - 4.7e-17 61.5 1.8 7.8e-17 60.8 0.1 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p vATP-synt_E PF01991.18 EAN30694.1 - 2.1e-35 122.0 9.7 2.5e-35 121.7 9.7 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit UPF0004 PF00919.20 EAN30694.1 - 0.017 15.2 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 AP2 PF00847.20 EAN30695.1 - 1.4e-10 41.2 3.9 2.5e-10 40.4 3.9 1.4 1 0 0 1 1 1 1 AP2 domain TMPIT PF07851.13 EAN30696.1 - 0.63 9.2 3.8 0.94 8.7 3.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein FHA PF00498.26 EAN30697.1 - 0.02 15.3 0.2 0.52 10.7 0.0 3.0 2 0 0 2 2 2 0 FHA domain NigD_N PF12667.7 EAN30697.1 - 0.12 12.5 2.4 1.3 9.2 0.3 2.8 2 1 0 2 2 2 0 NigD-like N-terminal OB domain polyprenyl_synt PF00348.17 EAN30698.1 - 4.3e-73 245.5 0.3 5.6e-73 245.2 0.3 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase MgpC PF05220.12 EAN30698.1 - 0.014 14.7 0.2 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 MgpC protein precursor MBF1 PF08523.10 EAN30699.1 - 8.2e-19 67.8 0.3 8.2e-19 67.8 0.3 1.5 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EAN30699.1 - 3.9e-06 26.8 0.2 6.6e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EAN30699.1 - 5e-05 23.6 0.0 0.00088 19.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 EAN30699.1 - 7e-05 22.8 1.1 0.00017 21.6 0.5 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Adaptin_binding PF10199.9 EAN30699.1 - 0.055 14.1 0.3 0.069 13.8 0.3 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 HTH_25 PF13413.6 EAN30699.1 - 0.1 12.4 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TFIIF_beta PF02270.15 EAN30700.1 - 0.0036 17.4 0.1 0.0071 16.5 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Arf PF00025.21 EAN30701.1 - 4.4e-10 39.3 0.0 4.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAN30701.1 - 5e-06 26.1 0.0 6.7e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EAN30701.1 - 1.9e-05 24.9 0.0 2.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EAN30701.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.19 EAN30701.1 - 0.16 11.6 0.1 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_S7 PF00177.21 EAN30702.1 - 6.6e-39 132.9 1.6 8.3e-39 132.6 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e FAINT PF04385.15 EAN30703.1 - 8.1e-24 83.5 22.9 1.6e-07 31.3 0.2 7.2 8 0 0 8 8 8 4 Domain of unknown function, DUF529 PT PF04886.12 EAN30703.1 - 8e-08 31.7 32.7 8e-08 31.7 32.7 5.3 4 1 1 5 5 5 2 PT repeat YrhC PF14143.6 EAN30704.1 - 0.039 14.0 6.8 0.026 14.6 3.5 2.6 2 0 0 2 2 2 0 YrhC-like protein FAINT PF04385.15 EAN30705.1 - 9.6e-89 291.5 186.4 3.2e-08 33.5 1.8 18.9 18 0 0 18 18 18 18 Domain of unknown function, DUF529 B_lectin PF01453.24 EAN30705.1 - 0.11 13.0 6.7 5.7 7.5 0.1 5.4 5 0 0 5 5 5 0 D-mannose binding lectin ADAM_spacer1 PF05986.14 EAN30705.1 - 0.16 12.0 2.2 0.69 10.0 1.8 2.4 2 0 0 2 2 2 0 ADAM-TS Spacer 1 ABC_tran PF00005.27 EAN30706.1 - 1.6e-31 109.6 0.0 8.9e-18 65.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EAN30706.1 - 1.6e-06 28.1 1.1 0.04 13.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EAN30706.1 - 1.8e-06 27.4 0.2 0.057 12.7 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin MeaB PF03308.16 EAN30706.1 - 5.8e-06 25.5 0.2 0.0037 16.3 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 EAN30706.1 - 0.00056 19.6 1.2 0.72 9.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EAN30706.1 - 0.00066 20.1 0.0 1.3 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EAN30706.1 - 0.00089 19.8 0.0 2.2 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 EAN30706.1 - 0.0029 16.8 1.1 0.46 9.6 0.0 2.9 3 0 0 3 3 2 1 NB-ARC domain AAA_25 PF13481.6 EAN30706.1 - 0.0056 16.3 0.0 12 5.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EAN30706.1 - 0.0076 16.3 0.6 0.19 11.8 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 EAN30706.1 - 0.0078 16.2 0.2 3.3 7.6 0.0 2.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EAN30706.1 - 0.012 15.8 1.6 1.2 9.4 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_30 PF13604.6 EAN30706.1 - 0.013 15.2 0.3 0.51 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EAN30706.1 - 0.022 13.8 0.1 2 7.4 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 EAN30706.1 - 0.029 14.9 3.2 0.58 10.6 0.9 2.5 2 0 0 2 2 2 0 AAA domain VraX PF17412.2 EAN30706.1 - 0.032 13.9 1.2 0.21 11.3 0.0 2.9 4 0 0 4 4 3 0 Family of unknown function DUF815 PF05673.13 EAN30706.1 - 0.039 13.1 0.6 0.17 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 EAN30706.1 - 0.055 13.5 0.8 10 6.2 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EAN30706.1 - 0.06 13.3 1.2 11 5.9 0.0 3.3 3 0 0 3 3 3 0 NACHT domain cobW PF02492.19 EAN30706.1 - 0.11 12.0 1.4 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EAN30706.1 - 0.17 12.1 2.4 13 6.0 0.3 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAN30706.1 - 0.17 11.3 0.4 7.3 6.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein MobB PF03205.14 EAN30706.1 - 0.18 11.7 2.6 1.6 8.6 0.2 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.9 EAN30706.1 - 0.19 10.6 1.6 4.5 6.1 0.3 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 EAN30706.1 - 0.24 11.4 0.8 4 7.4 0.2 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EAN30706.1 - 0.25 11.1 3.8 1.1 9.0 0.3 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 EAN30706.1 - 0.31 11.0 1.8 21 5.0 0.1 2.4 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 EAN30706.1 - 0.92 9.6 2.9 0.43 10.6 0.2 1.9 2 0 0 2 2 1 0 Helicase HerA, central domain FAINT PF04385.15 EAN30707.1 - 2.5e-35 120.4 59.8 2.3e-08 34.0 0.3 7.6 7 0 0 7 7 7 7 Domain of unknown function, DUF529 BBS2_Mid PF14783.6 EAN30707.1 - 0.04 14.0 2.2 0.24 11.5 0.4 2.9 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region FAINT PF04385.15 EAN30708.1 - 2.4e-06 27.5 12.2 0.01 15.9 4.1 3.0 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF5626 PF18540.1 EAN30708.1 - 0.018 15.6 3.3 0.027 15.0 0.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5626) Myc_N PF01056.18 EAN30708.1 - 0.27 11.1 4.6 0.37 10.7 4.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 EAN30708.1 - 0.77 9.0 17.8 1.4 8.2 17.8 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EAN30708.1 - 0.77 10.2 21.5 2 8.9 21.5 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 EAN30708.1 - 0.84 7.8 14.7 0.97 7.6 14.7 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EAN30708.1 - 1 8.7 13.3 1.3 8.4 13.3 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 EAN30708.1 - 1.8 8.2 13.4 2.8 7.6 13.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 EAN30708.1 - 2.5 6.3 7.3 3.1 6.0 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Tash_PEST PF07708.11 EAN30709.1 - 3.8e-08 33.2 0.7 2.1e-07 30.9 0.7 2.4 1 0 0 1 1 1 1 Tash protein PEST motif FAINT PF04385.15 EAN30709.1 - 6.8e-05 22.8 7.1 0.00062 19.8 0.4 3.8 2 2 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30710.1 - 1.1e-06 28.6 7.5 0.0016 18.4 1.1 2.9 2 1 1 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30711.1 - 4.4e-11 42.7 7.3 1.1e-06 28.6 0.9 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 CHU_C PF13585.6 EAN30711.1 - 0.16 12.0 1.7 0.4 10.8 1.7 1.6 1 1 0 1 1 1 0 C-terminal domain of CHU protein family FAINT PF04385.15 EAN30712.1 - 1.8e-05 24.7 4.2 0.054 13.5 0.1 3.1 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30713.1 - 1.7 8.7 11.4 0.055 13.5 3.1 2.6 2 0 0 2 2 2 0 Domain of unknown function, DUF529 DUF4195 PF13836.6 EAN30714.1 - 0.26 11.4 1.7 0.49 10.5 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) Uteroglobin PF01099.17 EAN30714.1 - 0.52 10.7 6.3 6 7.3 1.0 2.6 2 0 0 2 2 2 0 Uteroglobin family Cwf_Cwc_15 PF04889.12 EAN30714.1 - 5.8 6.6 11.8 0.97 9.1 3.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAINT PF04385.15 EAN30715.1 - 0.082 13.0 16.0 0.19 11.8 3.9 3.0 2 1 0 2 2 2 0 Domain of unknown function, DUF529 GAGA_bind PF06217.12 EAN30715.1 - 3.8 7.7 7.5 11 6.2 7.5 1.7 1 0 0 1 1 1 0 GAGA binding protein-like family FAINT PF04385.15 EAN30716.1 - 0.0011 18.9 10.7 0.018 15.1 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DTHCT PF08070.11 EAN30716.1 - 0.67 10.7 6.3 0.44 11.3 2.2 2.4 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF3221 PF11518.8 EAN30716.1 - 2.5 8.5 5.2 1.4 9.3 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3221) FAINT PF04385.15 EAN30717.1 - 0.0025 17.8 0.3 0.0061 16.6 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Presenilin PF01080.17 EAN30717.1 - 0.011 14.6 0.4 0.011 14.6 0.4 2.5 2 1 0 2 2 2 0 Presenilin CDC45 PF02724.14 EAN30717.1 - 1.8 6.7 8.6 4.8 5.4 8.6 1.6 1 0 0 1 1 1 0 CDC45-like protein Synapsin PF02078.16 EAN30719.1 - 0.035 14.4 0.3 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Synapsin, N-terminal domain FAINT PF04385.15 EAN30719.1 - 0.036 14.1 0.8 0.036 14.1 0.8 5.0 3 2 3 6 6 6 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30720.1 - 0.082 13.0 16.0 0.19 11.8 3.9 3.0 2 1 0 2 2 2 0 Domain of unknown function, DUF529 Spore_GerQ PF09671.10 EAN30720.1 - 0.091 12.8 0.4 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) GAGA_bind PF06217.12 EAN30720.1 - 3.8 7.7 7.5 11 6.2 7.5 1.7 1 0 0 1 1 1 0 GAGA binding protein-like family FAINT PF04385.15 EAN30721.1 - 0.0011 18.9 10.7 0.018 15.1 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DTHCT PF08070.11 EAN30721.1 - 0.67 10.7 6.3 0.44 11.3 2.2 2.4 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF3221 PF11518.8 EAN30721.1 - 2.5 8.5 5.2 1.4 9.3 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3221) FAINT PF04385.15 EAN30722.1 - 0.0002 21.3 6.2 0.0078 16.2 0.3 2.7 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30723.1 - 8.3e-06 25.8 11.1 0.00025 21.0 0.8 3.0 1 1 2 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30724.1 - 0.00042 20.3 1.2 0.00042 20.3 1.2 3.5 3 1 1 4 4 4 1 Domain of unknown function, DUF529 Tir_receptor_C PF07489.11 EAN30724.1 - 0.083 12.9 2.2 0.19 11.7 2.2 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus FAINT PF04385.15 EAN30725.1 - 0.00041 20.3 7.8 0.0018 18.3 1.5 2.7 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30726.1 - 1.7 8.7 11.4 0.055 13.5 3.1 2.6 2 0 0 2 2 2 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30727.1 - 0.00062 19.8 10.9 0.0087 16.1 3.5 3.2 2 1 0 2 2 2 2 Domain of unknown function, DUF529 DUF4195 PF13836.6 EAN30727.1 - 0.33 11.1 1.8 0.64 10.1 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) Uteroglobin PF01099.17 EAN30727.1 - 0.74 10.2 6.4 7.1 7.0 1.0 2.6 2 0 0 2 2 2 0 Uteroglobin family FAINT PF04385.15 EAN30728.1 - 2.2e-05 24.4 10.9 6.4e-05 22.9 1.1 3.1 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30729.1 - 2.5e-10 40.3 7.8 6.4e-08 32.6 1.0 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN30731.1 - 2e-07 30.9 1.0 2e-07 30.9 1.0 3.0 4 0 0 4 4 4 1 Tash protein PEST motif FAINT PF04385.15 EAN30731.1 - 5.9e-06 26.2 0.8 5.9e-06 26.2 0.8 3.6 2 1 1 3 3 3 1 Domain of unknown function, DUF529 Cna_B PF05738.13 EAN30731.1 - 0.24 12.0 4.1 4 8.0 0.2 3.5 3 1 0 3 3 3 0 Cna protein B-type domain Tash_PEST PF07708.11 EAN30732.1 - 0.00017 21.6 7.4 0.00034 20.7 7.4 1.6 1 0 0 1 1 1 1 Tash protein PEST motif SpoIIIAH PF12685.7 EAN30733.1 - 0.062 13.1 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein FAINT PF04385.15 EAN30734.1 - 0.03 14.4 0.6 0.03 14.4 0.6 2.8 3 1 0 3 3 3 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30736.1 - 0.00047 20.2 0.4 0.00047 20.2 0.4 3.5 2 1 2 4 4 4 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30737.1 - 7.9e-06 25.9 4.2 2.4e-05 24.3 0.9 2.6 2 0 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30738.1 - 8.8e-05 22.5 2.0 8.8e-05 22.5 2.0 2.9 2 0 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30739.1 - 0.0019 18.2 2.5 0.0019 18.2 2.5 3.7 2 1 0 2 2 2 1 Domain of unknown function, DUF529 RsbU_N PF08673.10 EAN30739.1 - 0.12 12.5 4.0 10 6.3 0.0 3.3 3 0 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain Flu_B_M2 PF04772.12 EAN30739.1 - 3.6 7.9 5.4 13 6.1 2.4 2.7 3 1 0 3 3 3 0 Influenza B matrix protein 2 (BM2) FAINT PF04385.15 EAN30740.1 - 5.1e-09 36.1 7.7 9.6e-05 22.4 2.1 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30741.1 - 0.036 14.1 0.3 0.036 14.1 0.3 2.8 1 1 1 2 2 2 0 Domain of unknown function, DUF529 TFIIA PF03153.13 EAN30741.1 - 0.44 10.5 30.9 0.6 10.1 30.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1911 PF08929.10 EAN30741.1 - 2.1 9.2 6.6 1.5 9.6 4.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) FAINT PF04385.15 EAN30742.1 - 4.2e-09 36.4 16.2 5.6e-05 23.1 4.2 3.2 2 1 0 2 2 2 2 Domain of unknown function, DUF529 Putative_G5P PF17426.2 EAN30742.1 - 0.019 15.0 0.7 0.05 13.7 0.2 2.0 1 1 1 2 2 2 0 Putative Gamma DNA binding protein G5P ABC_tran PF00005.27 EAN30743.1 - 2.1e-32 112.5 0.0 1.5e-17 64.4 0.0 2.6 2 1 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EAN30743.1 - 1.6e-07 31.4 0.6 0.0078 16.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EAN30743.1 - 3e-06 26.7 0.1 0.011 15.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin MeaB PF03308.16 EAN30743.1 - 8.1e-05 21.7 0.2 0.0088 15.0 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 EAN30743.1 - 9e-05 22.1 1.8 0.1 12.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EAN30743.1 - 0.00029 20.8 1.3 1 9.1 0.3 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_10 PF12846.7 EAN30743.1 - 0.0013 17.7 0.5 1.4 7.7 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_30 PF13604.6 EAN30743.1 - 0.0019 18.0 0.2 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EAN30743.1 - 0.0023 17.9 0.1 1.4 8.8 0.0 2.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 EAN30743.1 - 0.0028 17.7 0.7 0.3 11.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAN30743.1 - 0.0031 17.9 0.0 2.6 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAN30743.1 - 0.0046 17.2 1.0 0.87 9.9 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA_23 PF13476.6 EAN30743.1 - 0.0057 17.2 6.7 0.65 10.5 1.2 3.0 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EAN30743.1 - 0.0067 15.5 0.5 0.92 8.5 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 EAN30743.1 - 0.0074 16.8 0.0 4.1 7.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 EAN30743.1 - 0.0088 15.0 0.6 2.7 6.8 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 EAN30743.1 - 0.01 16.0 5.1 0.46 10.5 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 EAN30743.1 - 0.023 14.3 2.0 1.8 8.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EAN30743.1 - 0.025 13.8 0.8 0.32 10.2 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 EAN30743.1 - 0.035 13.5 0.2 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 EAN30743.1 - 0.048 13.7 0.3 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EAN30743.1 - 0.048 13.6 3.1 8.4 6.3 0.1 3.2 3 0 0 3 3 3 0 NTPase Dynamin_N PF00350.23 EAN30743.1 - 0.09 12.8 1.6 0.72 9.9 0.4 2.7 2 0 0 2 2 2 0 Dynamin family MobB PF03205.14 EAN30743.1 - 0.11 12.4 2.1 1.8 8.5 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 EAN30743.1 - 0.16 12.3 0.6 27 5.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAN30743.1 - 0.18 11.3 0.0 14 5.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 EAN30743.1 - 0.21 11.5 3.5 14 5.6 0.0 3.2 4 0 0 4 4 3 0 NACHT domain SMC_N PF02463.19 EAN30743.1 - 0.26 10.7 5.0 0.098 12.1 0.5 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ATP_bind_1 PF03029.17 EAN30743.1 - 1.1 9.0 4.2 13 5.5 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Syndecan PF01034.20 EAN30744.1 - 0.12 12.3 0.4 0.33 10.9 0.4 1.8 1 0 0 1 1 1 0 Syndecan domain FAINT PF04385.15 EAN30745.1 - 3.8e-12 46.1 14.3 8.7e-06 25.7 5.3 2.8 2 1 1 3 3 3 2 Domain of unknown function, DUF529 Archease PF01951.16 EAN30746.1 - 4e-44 150.2 0.1 5.8e-44 149.7 0.1 1.2 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Ribosomal_L27A PF00828.19 EAN30747.1 - 1.5e-17 64.5 0.0 4.1e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF1798 PF08807.10 EAN30747.1 - 0.055 13.6 0.6 0.13 12.4 0.6 1.6 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Ribosomal_L17 PF01196.19 EAN30748.1 - 1.7e-21 76.9 1.0 2.3e-21 76.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 AFG1_ATPase PF03969.16 EAN30749.1 - 4.7e-67 226.4 0.1 1.6e-63 214.8 0.0 2.6 2 1 0 2 2 2 2 AFG1-like ATPase AAA PF00004.29 EAN30749.1 - 0.00063 20.2 0.0 0.0016 18.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAN30749.1 - 0.00068 19.9 0.3 0.003 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EAN30749.1 - 0.0033 17.4 0.7 0.0084 16.0 0.1 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EAN30749.1 - 0.0096 15.8 0.6 0.053 13.4 0.0 2.6 3 1 0 3 3 3 1 NACHT domain CobA_CobO_BtuR PF02572.15 EAN30749.1 - 0.032 14.5 1.4 0.11 12.7 1.4 1.9 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP CholecysA-Rec_N PF09193.10 EAN30749.1 - 0.12 12.4 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal ABC_tran PF00005.27 EAN30749.1 - 0.12 12.9 0.3 0.68 10.5 0.3 2.1 1 1 0 1 1 1 0 ABC transporter Bac_DnaA PF00308.18 EAN30749.1 - 0.72 9.7 9.0 2 8.2 0.2 3.1 3 1 1 4 4 4 0 Bacterial dnaA protein Chromo PF00385.24 EAN30750.1 - 7e-20 70.7 5.3 2.5e-14 52.9 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 EAN30750.1 - 4.7e-05 23.4 0.7 0.011 15.8 0.0 3.4 4 0 0 4 4 4 2 Chromo shadow domain LON_substr_bdg PF02190.16 EAN30751.1 - 3.3e-06 27.1 0.4 9e-06 25.7 0.1 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain DNA_RNApol_7kD PF03604.13 EAN30752.1 - 9e-18 63.7 3.9 1.2e-17 63.3 3.9 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 EAN30752.1 - 0.0008 19.4 0.2 0.00097 19.1 0.2 1.1 1 0 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.10 EAN30752.1 - 0.0012 18.9 0.4 0.0021 18.2 0.4 1.4 1 0 0 1 1 1 1 Zinc ribbon domain HypA PF01155.19 EAN30752.1 - 0.0017 18.4 0.2 0.002 18.2 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1451 PF07295.11 EAN30752.1 - 0.0034 17.4 0.1 0.0037 17.3 0.1 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain zinc_ribbon_10 PF10058.9 EAN30752.1 - 0.0084 15.8 0.2 0.27 11.0 0.0 2.1 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 EAN30752.1 - 0.012 15.1 0.7 3.3 7.3 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 EAN30752.1 - 0.012 15.0 2.1 0.04 13.3 2.2 1.8 1 1 0 1 1 1 0 zinc-ribbon domain GFA PF04828.14 EAN30752.1 - 0.012 15.9 0.4 2 8.8 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TackOD1 PF18551.1 EAN30752.1 - 0.019 14.7 0.2 0.021 14.5 0.2 1.0 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 OrfB_Zn_ribbon PF07282.11 EAN30752.1 - 0.02 14.8 0.8 0.023 14.6 0.8 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain TFIIS_C PF01096.18 EAN30752.1 - 0.031 14.1 0.3 7.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2688 PF10892.8 EAN30752.1 - 0.039 13.4 1.7 1.6 8.3 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) A2L_zn_ribbon PF08792.10 EAN30752.1 - 0.041 13.6 2.9 0.27 11.0 2.5 2.0 1 1 1 2 2 2 0 A2L zinc ribbon domain zf_UBZ PF18439.1 EAN30752.1 - 0.043 13.4 1.0 1.8 8.3 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Rubredoxin_2 PF18073.1 EAN30752.1 - 0.046 13.4 4.5 1.9 8.3 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc-ribbon_6 PF10005.9 EAN30752.1 - 0.05 14.3 0.2 0.063 14.0 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain HECT_2 PF09814.9 EAN30752.1 - 0.05 12.5 0.1 0.052 12.4 0.1 1.2 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Zn_ribbon_SprT PF17283.2 EAN30752.1 - 0.051 13.5 3.2 0.092 12.7 3.2 1.5 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-ISL3 PF14690.6 EAN30752.1 - 0.065 13.9 1.6 0.22 12.2 0.2 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Ribosomal_L32p PF01783.23 EAN30752.1 - 0.1 12.9 1.3 0.24 11.7 0.1 1.9 1 1 1 2 2 2 0 Ribosomal L32p protein family zinc_ribbon_2 PF13240.6 EAN30752.1 - 0.14 11.9 4.4 7.4 6.4 4.3 2.2 1 1 1 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 EAN30752.1 - 0.17 11.9 2.2 1.7 8.7 0.3 2.1 1 1 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_13 PF09855.9 EAN30752.1 - 0.18 12.0 2.0 0.26 11.5 0.1 1.9 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Zn_ribbon_recom PF13408.6 EAN30752.1 - 0.95 10.0 10.0 1.3 9.6 2.3 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain PhnA_Zn_Ribbon PF08274.12 EAN30752.1 - 1.1 9.2 4.1 5.3 7.1 1.1 2.4 1 1 1 2 2 2 0 PhnA Zinc-Ribbon zf-CCHC PF00098.23 EAN30752.1 - 9.7 6.5 9.6 2.4 8.4 0.5 2.2 2 0 0 2 2 2 0 Zinc knuckle PUB PF09409.10 EAN30753.1 - 4.2e-05 23.4 0.1 0.00014 21.7 0.1 1.9 1 0 0 1 1 1 1 PUB domain CODH_A_N PF18537.1 EAN30753.1 - 0.032 14.2 0.1 15 5.7 0.0 3.4 3 0 0 3 3 3 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain DUF1664 PF07889.12 EAN30755.1 - 0.049 13.7 4.6 0.28 11.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) WBS_methylT PF12589.8 EAN30756.1 - 2.4e-10 41.0 3.1 4e-10 40.3 3.1 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 EAN30756.1 - 1.1e-06 29.3 0.0 2.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAN30756.1 - 1.1e-06 29.1 0.0 2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 EAN30756.1 - 4.4e-05 23.3 2.0 0.033 13.9 0.0 2.2 2 0 0 2 2 2 2 DNA methylase Methyltransf_12 PF08242.12 EAN30756.1 - 7e-05 23.5 0.0 0.00014 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAN30756.1 - 0.00076 19.3 0.2 0.0022 17.8 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAN30756.1 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAN30756.1 - 0.06 12.7 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MOR2-PAG1_C PF14225.6 EAN30757.1 - 0.13 12.1 0.3 0.29 11.0 0.3 1.5 1 0 0 1 1 1 0 Cell morphogenesis C-terminal DUF2391 PF09622.10 EAN30757.1 - 8 5.7 8.4 1.1 8.5 4.0 1.7 2 0 0 2 2 2 0 Putative integral membrane protein (DUF2391) BRE1 PF08647.11 EAN30758.1 - 9.7e-07 28.8 9.7 0.032 14.3 1.0 4.0 1 1 2 4 4 4 4 BRE1 E3 ubiquitin ligase HrpB7 PF09486.10 EAN30758.1 - 3.9e-06 27.3 11.1 0.069 13.5 0.9 3.3 1 1 2 3 3 3 3 Bacterial type III secretion protein (HrpB7) DUF16 PF01519.16 EAN30758.1 - 1e-05 25.9 26.6 0.027 15.0 4.0 3.8 1 1 2 3 3 3 3 Protein of unknown function DUF16 XhlA PF10779.9 EAN30758.1 - 3.8e-05 23.8 22.2 0.037 14.2 2.6 4.4 1 1 5 6 6 6 3 Haemolysin XhlA Tropomyosin_1 PF12718.7 EAN30758.1 - 0.00025 21.2 26.1 0.053 13.7 5.7 4.0 1 1 2 3 3 3 3 Tropomyosin like CLZ PF16526.5 EAN30758.1 - 0.00062 20.1 1.0 2.9 8.3 0.1 3.9 1 1 4 5 5 5 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_13 PF13166.6 EAN30758.1 - 0.00083 18.1 20.7 0.0013 17.4 19.4 1.7 1 1 0 1 1 1 1 AAA domain DUF724 PF05266.14 EAN30758.1 - 0.0022 17.9 23.9 0.035 13.9 3.2 3.3 1 1 3 4 4 4 3 Protein of unknown function (DUF724) Tropomyosin PF00261.20 EAN30758.1 - 0.0025 17.2 24.9 0.012 15.0 3.4 3.1 1 1 2 3 3 3 2 Tropomyosin PI3K_P85_iSH2 PF16454.5 EAN30758.1 - 0.0026 17.4 14.0 0.3 10.7 1.7 3.4 1 1 2 3 3 3 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ERM PF00769.19 EAN30758.1 - 0.0059 16.5 13.9 0.0093 15.8 12.1 2.0 1 1 0 1 1 1 1 Ezrin/radixin/moesin family ATG16 PF08614.11 EAN30758.1 - 0.0062 16.8 3.8 0.0062 16.8 3.8 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) PEARLI-4 PF05278.12 EAN30758.1 - 0.0083 15.7 14.7 0.3 10.6 2.9 3.0 1 1 3 4 4 4 4 Arabidopsis phospholipase-like protein (PEARLI 4) DUF1664 PF07889.12 EAN30758.1 - 0.013 15.5 20.1 0.34 10.9 5.3 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 EAN30758.1 - 0.018 15.7 13.3 0.15 12.7 2.1 3.4 1 1 4 5 5 5 0 SlyX APG6_N PF17675.1 EAN30758.1 - 0.019 15.5 21.7 0.71 10.4 3.4 3.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Laminin_II PF06009.12 EAN30758.1 - 0.033 14.2 15.2 0.11 12.5 5.8 2.8 1 1 3 4 4 4 0 Laminin Domain II Nsp1_C PF05064.13 EAN30758.1 - 0.037 13.8 13.2 1.6 8.5 2.1 3.4 1 1 2 3 3 3 0 Nsp1-like C-terminal region DUF3251 PF11622.8 EAN30758.1 - 0.063 12.9 4.4 27 4.4 0.1 3.9 1 1 2 4 4 4 0 Protein of unknown function (DUF3251) CENP-F_leu_zip PF10473.9 EAN30758.1 - 0.072 13.1 20.6 0.54 10.3 5.3 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 EAN30758.1 - 0.074 13.4 29.4 0.96 9.9 5.6 4.9 1 1 4 5 5 5 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 EAN30758.1 - 0.088 13.1 40.4 5.9 7.2 2.6 6.4 1 1 6 7 7 7 0 ABC transporter C-terminal domain DUF2730 PF10805.8 EAN30758.1 - 0.11 12.6 11.0 3.3 7.9 1.2 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Fez1 PF06818.15 EAN30758.1 - 0.11 12.9 13.4 1.1 9.7 5.2 2.7 1 1 1 2 2 2 0 Fez1 FliJ PF02050.16 EAN30758.1 - 0.12 12.6 4.1 0.58 10.4 0.1 3.2 2 1 1 3 3 3 0 Flagellar FliJ protein DUF2552 PF10827.8 EAN30758.1 - 0.13 12.5 0.2 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) CCDC-167 PF15188.6 EAN30758.1 - 0.17 12.3 35.2 2.3 8.6 2.2 5.9 2 1 7 9 9 8 0 Coiled-coil domain-containing protein 167 DUF812 PF05667.11 EAN30758.1 - 0.23 10.3 24.2 0.13 11.1 13.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Lectin_N PF03954.14 EAN30758.1 - 0.23 11.2 1.7 50 3.6 0.0 3.9 1 1 3 4 4 4 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 EAN30758.1 - 0.3 11.3 24.3 1.6 8.9 3.9 4.0 2 1 2 4 4 3 0 Fibrinogen alpha/beta chain family Sigma54_AID PF00309.20 EAN30758.1 - 0.34 10.8 3.8 0.33 10.9 1.4 2.2 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) DUF2849 PF11011.8 EAN30758.1 - 0.38 11.4 10.5 11 6.8 0.4 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF2849) Cluap1 PF10234.9 EAN30758.1 - 0.54 9.6 16.3 1.5 8.2 2.1 3.3 1 1 2 3 3 3 0 Clusterin-associated protein-1 DUF4164 PF13747.6 EAN30758.1 - 0.76 10.1 10.4 6.1 7.2 3.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) PriC PF07445.12 EAN30758.1 - 1.7 8.6 8.3 22 4.9 0.3 3.1 1 1 2 3 3 3 0 Primosomal replication protein priC TMPIT PF07851.13 EAN30758.1 - 1.8 7.7 9.5 62 2.7 9.4 2.4 1 1 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 EAN30758.1 - 1.8 7.8 11.5 2.2 7.6 1.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DivIC PF04977.15 EAN30758.1 - 1.9 8.3 26.0 0.65 9.8 3.3 4.9 1 1 4 5 5 5 0 Septum formation initiator DUF4140 PF13600.6 EAN30758.1 - 3.1 8.3 19.3 4.6e+03 -1.9 0.1 4.2 1 1 1 2 2 0 0 N-terminal domain of unknown function (DUF4140) bZIP_2 PF07716.15 EAN30758.1 - 3.5 7.8 7.0 1.1e+02 3.0 0.4 4.2 1 1 5 6 6 6 0 Basic region leucine zipper BLOC1_2 PF10046.9 EAN30758.1 - 4.2 7.7 15.3 22 5.4 6.4 3.8 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ax_dynein_light PF10211.9 EAN30758.1 - 5.2 7.0 20.7 2.7 7.9 1.0 3.8 1 1 4 5 5 5 0 Axonemal dynein light chain Snapin_Pallidin PF14712.6 EAN30758.1 - 5.3 7.5 11.3 9.2 6.8 3.4 3.5 1 1 2 3 3 3 0 Snapin/Pallidin zf-C4H2 PF10146.9 EAN30758.1 - 5.3 7.3 26.0 2.8 8.2 12.2 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein DUF5082 PF16888.5 EAN30758.1 - 5.9 7.2 21.2 36 4.7 5.8 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) Atg14 PF10186.9 EAN30758.1 - 7.6 5.5 12.3 4.3 6.3 8.0 2.4 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 U3_assoc_6 PF08640.11 EAN30759.1 - 3.2e-14 52.8 1.1 8.1e-14 51.5 0.0 2.2 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 Suf PF05843.14 EAN30759.1 - 0.066 13.2 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NARP1 PF12569.8 EAN30760.1 - 0.19 10.6 2.1 0.23 10.3 2.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Flu_B_NS1 PF02942.14 EAN30760.1 - 0.46 9.5 4.0 0.52 9.3 4.0 1.1 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) UQ_con PF00179.26 EAN30761.1 - 5e-14 52.1 0.0 6e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAN30761.1 - 0.16 12.3 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain NIF PF03031.18 EAN30762.1 - 2.9e-53 179.8 0.0 3.8e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RNA_pol_L_2 PF13656.6 EAN30763.1 - 9.2e-22 76.6 0.0 1.2e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Viral_NABP PF05515.11 EAN30763.1 - 0.012 15.5 0.0 0.013 15.3 0.0 1.0 1 0 0 1 1 1 0 Viral nucleic acid binding RNA_pol_L PF01193.24 EAN30763.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain SH3_14 PF18343.1 EAN30764.1 - 0.033 14.3 1.9 0.05 13.7 0.2 2.2 2 0 0 2 2 2 0 Dda helicase SH3 domain HCMV_UL139 PF12507.8 EAN30764.1 - 0.11 12.9 0.4 0.22 11.9 0.4 1.5 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein Adaptin_binding PF10199.9 EAN30764.1 - 1.5 9.4 6.9 5.9 7.5 6.9 1.9 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 AP2 PF00847.20 EAN30768.1 - 2e-06 27.9 2.9 0.013 15.7 0.3 2.7 2 0 0 2 2 2 2 AP2 domain V-ATPase_H_N PF03224.14 EAN30769.1 - 1.3e-38 133.1 21.4 1.3e-38 133.1 21.4 2.1 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EAN30769.1 - 1e-31 109.5 4.4 1.8e-19 70.0 0.6 3.9 4 1 1 5 5 5 2 V-ATPase subunit H DUF3545 PF12065.8 EAN30770.1 - 0.0012 18.9 2.2 0.0031 17.5 2.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3545) RED_N PF07808.13 EAN30771.1 - 7.1e-12 45.4 0.0 8.7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 RED-like protein N-terminal region RRM_1 PF00076.22 EAN30772.1 - 1.5e-09 37.5 0.0 1.3e-05 24.9 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_6 PF15985.5 EAN30773.1 - 4.3e-05 23.8 0.1 7.1e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 KH domain Mlh1_C PF16413.5 EAN30774.1 - 0.02 14.3 3.4 0.13 11.6 1.0 2.6 3 0 0 3 3 3 0 DNA mismatch repair protein Mlh1 C-terminus APC1_C PF18122.1 EAN30774.1 - 0.05 13.6 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain CDC45 PF02724.14 EAN30774.1 - 2.8 6.2 6.3 3.9 5.6 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5041 PF16444.5 EAN30775.1 - 1.2 9.4 5.4 0.14 12.4 1.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5041) DUF2681 PF10883.8 EAN30775.1 - 3.4 8.1 13.8 2.4 8.6 6.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF489 PF04356.12 EAN30776.1 - 0.042 13.8 4.1 0.15 12.0 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF489) E7 PF00527.18 EAN30776.1 - 0.066 13.4 0.4 0.16 12.2 0.4 1.7 1 0 0 1 1 1 0 E7 protein, Early protein FAM176 PF14851.6 EAN30776.1 - 0.18 11.5 2.6 0.36 10.5 2.6 1.5 1 0 0 1 1 1 0 FAM176 family Serine_rich PF08824.10 EAN30776.1 - 0.26 11.3 1.7 1.5 8.8 0.1 2.1 2 0 0 2 2 2 0 Serine rich protein interaction domain RNA_polI_A34 PF08208.11 EAN30776.1 - 1.4 8.9 8.0 1.7 8.7 5.8 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 NOA36 PF06524.12 EAN30776.1 - 2.1 7.6 5.9 3.3 7.0 5.9 1.2 1 0 0 1 1 1 0 NOA36 protein MapZ_EC1 PF18041.1 EAN30776.1 - 3.4 7.9 9.6 1.2 9.4 1.4 2.8 2 1 0 2 2 2 0 MapZ extracellular domain 1 CENP-B_dimeris PF09026.10 EAN30776.1 - 3.8 8.0 10.0 9.3 6.7 10.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DASH_Spc19 PF08287.11 EAN30776.1 - 6.2 6.7 12.5 0.15 12.0 2.1 2.7 3 0 0 3 3 3 0 Spc19 Z1 PF10593.9 EAN30778.1 - 0.012 15.1 1.7 0.014 14.9 1.7 1.1 1 0 0 1 1 1 0 Z1 domain PET117 PF15786.5 EAN30778.1 - 0.085 13.1 2.2 0.12 12.7 2.2 1.4 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Trypan_PARP PF05887.11 EAN30778.1 - 0.35 10.9 12.6 2.9 7.9 5.5 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Arc_PepC_II PF06847.11 EAN30778.1 - 0.36 11.4 2.3 0.63 10.6 2.3 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Minor_tail_Z PF06763.11 EAN30778.1 - 0.37 10.6 2.3 0.61 9.9 1.7 1.6 1 1 0 1 1 1 0 Prophage minor tail protein Z (GPZ) COQ7 PF03232.13 EAN30778.1 - 0.38 10.5 6.5 0.55 10.0 6.5 1.3 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Goodbye PF17109.5 EAN30778.1 - 0.52 10.8 2.7 0.8 10.2 2.7 1.3 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Atrophin-1 PF03154.15 EAN30778.1 - 0.92 7.7 12.8 1.1 7.4 12.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.6 EAN30778.1 - 1.2 9.2 4.6 2.1 8.4 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) CDI PF02234.19 EAN30778.1 - 1.4 9.2 12.3 0.8 10.0 4.7 2.3 1 1 1 2 2 2 0 Cyclin-dependent kinase inhibitor MMtag PF10159.9 EAN30779.1 - 2.7e-20 72.4 2.3 3e-20 72.3 2.3 1.0 1 0 0 1 1 1 1 Multiple myeloma tumor-associated MSA-2c PF12238.8 EAN30779.1 - 0.12 12.4 0.8 0.14 12.2 0.8 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Hyr1 PF15789.5 EAN30780.1 - 0.12 12.0 1.9 0.32 10.6 0.4 2.2 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 CSN8_PSD8_EIF3K PF10075.9 EAN30782.1 - 2.4e-11 43.8 1.4 5.2e-11 42.7 0.5 2.0 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EAN30782.1 - 0.0029 17.1 1.8 0.0029 17.1 1.8 2.3 1 1 1 2 2 2 1 SAC3/GANP family UpxZ PF06603.11 EAN30782.1 - 0.022 15.0 1.2 0.066 13.5 1.2 1.8 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists RNase_3_N PF18497.1 EAN30782.1 - 0.027 14.7 1.1 0.027 14.7 1.1 2.2 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain Fzo_mitofusin PF04799.13 EAN30782.1 - 0.052 13.1 2.3 0.11 12.0 2.3 1.5 1 0 0 1 1 1 0 fzo-like conserved region Seryl_tRNA_N PF02403.22 EAN30782.1 - 1.4 9.2 6.3 0.64 10.3 2.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 EAN30783.1 - 1.5e-60 204.8 0.0 1.9e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN30783.1 - 5.4e-26 91.4 0.0 1.1e-16 60.9 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EAN30783.1 - 0.00053 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAN30783.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EAN30783.1 - 0.011 15.0 0.0 0.033 13.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 EAN30783.1 - 0.039 13.5 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 EAN30783.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC1 family CPSase_L_D2 PF02786.17 EAN30784.1 - 4.3e-92 307.4 0.1 9.2e-70 234.4 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EAN30784.1 - 3.9e-41 139.9 0.0 1.3e-40 138.2 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 EAN30784.1 - 3.5e-31 108.1 0.2 7.3e-31 107.1 0.2 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GATase PF00117.28 EAN30784.1 - 4.7e-29 101.5 0.0 2.2e-28 99.3 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I ATPgrasp_Ter PF15632.6 EAN30784.1 - 1.5e-11 44.2 0.4 9.2e-07 28.7 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 EAN30784.1 - 1.6e-10 40.8 0.0 5.1e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EAN30784.1 - 1.5e-09 37.7 0.3 1.5e-06 27.9 0.1 3.2 2 1 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 EAN30784.1 - 1.9e-06 28.0 0.1 4.2e-05 23.6 0.0 2.9 2 1 0 2 2 1 1 MGS-like domain DJ-1_PfpI PF01965.24 EAN30784.1 - 0.00064 19.6 0.0 0.041 13.7 0.0 2.7 2 0 0 2 2 2 1 DJ-1/PfpI family ATP-grasp_3 PF02655.14 EAN30784.1 - 0.0024 18.0 0.6 0.1 12.6 0.2 2.9 3 0 0 3 3 3 1 ATP-grasp domain Peptidase_C26 PF07722.13 EAN30784.1 - 0.011 15.5 2.6 0.21 11.3 0.2 2.9 2 1 0 2 2 2 0 Peptidase C26 DCP2 PF05026.13 EAN30785.1 - 3.3e-21 75.4 1.0 3.3e-21 75.4 1.0 1.9 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 EAN30785.1 - 8e-15 55.0 0.0 1.9e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Ribosomal_L24e PF01246.20 EAN30786.1 - 1.4e-23 82.9 2.6 1.4e-23 82.9 2.6 2.3 2 0 0 2 2 2 1 Ribosomal protein L24e SPAM PF02090.15 EAN30786.1 - 0.076 12.8 2.8 0.1 12.4 2.8 1.1 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein CENP-H PF05837.12 EAN30787.1 - 0.00074 19.9 1.7 0.00074 19.9 1.7 1.8 2 1 0 2 2 2 1 Centromere protein H (CENP-H) Taxilin PF09728.9 EAN30787.1 - 0.0057 15.9 0.4 0.006 15.8 0.4 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DivIC PF04977.15 EAN30787.1 - 0.033 14.0 1.8 0.073 12.9 1.8 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF4795 PF16043.5 EAN30787.1 - 0.034 13.7 0.7 0.075 12.6 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Phage_GP20 PF06810.11 EAN30787.1 - 0.046 13.5 0.5 0.088 12.6 0.5 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 YabA PF06156.13 EAN30787.1 - 0.1 13.2 0.8 0.18 12.5 0.3 1.7 2 0 0 2 2 2 0 Initiation control protein YabA Ribosomal_S27e PF01667.17 EAN30788.1 - 7.7e-24 83.2 5.4 9.4e-24 82.9 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 EAN30788.1 - 0.01 15.4 0.4 0.015 14.8 0.4 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding dsDNA_bind PF01984.20 EAN30789.1 - 3.3e-18 66.0 8.9 3.6e-18 65.9 8.9 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4332 PF14229.6 EAN30789.1 - 0.0019 18.4 0.7 0.0031 17.7 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4332) UPF0223 PF05256.12 EAN30790.1 - 0.027 14.8 0.6 1.9 8.9 0.1 3.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0223) BLYB PF05289.11 EAN30791.1 - 0.16 12.2 0.8 0.83 9.9 0.1 2.4 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein HAND PF09110.11 EAN30791.1 - 0.52 11.1 4.8 0.16 12.7 0.7 2.2 2 0 0 2 2 2 0 HAND Asp PF00026.23 EAN30792.1 - 8.5e-63 212.7 0.0 1.3e-62 212.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAN30792.1 - 7.2e-10 39.4 5.6 2.7e-09 37.5 0.3 3.6 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EAN30792.1 - 0.00018 21.3 0.0 0.0015 18.4 0.0 2.6 4 0 0 4 4 4 1 Xylanase inhibitor C-terminal DUF3403 PF11883.8 EAN30792.1 - 0.18 12.0 0.0 0.56 10.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3403) AFP_2 PF18815.1 EAN30792.1 - 0.29 11.4 1.6 1 9.6 0.6 2.3 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat IspD PF01128.19 EAN30793.1 - 3.7e-30 105.3 0.0 1.7e-26 93.4 0.0 2.5 3 0 0 3 3 3 2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 EAN30793.1 - 0.18 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain EF-hand_1 PF00036.32 EAN30794.1 - 1.4e-25 86.8 9.0 6.5e-08 31.6 0.6 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EAN30794.1 - 1.4e-22 80.0 2.6 7.2e-14 52.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAN30794.1 - 5.1e-21 72.8 2.6 2.2e-07 30.2 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EAN30794.1 - 1.5e-17 63.2 6.8 2.8e-08 33.5 0.6 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EAN30794.1 - 6.2e-15 53.9 6.8 2.5e-05 23.5 0.0 4.0 3 1 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EAN30794.1 - 4.2e-12 46.2 0.0 5.4e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 EAN30794.1 - 0.00057 19.9 0.1 0.053 13.6 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 EAN30794.1 - 0.0016 18.6 0.9 2.9 8.1 0.2 2.8 1 1 2 3 3 3 3 Dockerin type I domain EF-hand_4 PF12763.7 EAN30794.1 - 0.0017 18.2 2.0 3.7 7.6 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SurA_N_2 PF13623.6 EAN30794.1 - 0.0031 17.4 1.3 0.13 12.2 0.1 2.3 1 1 0 2 2 2 1 SurA N-terminal domain SurA_N_3 PF13624.6 EAN30794.1 - 0.0042 16.9 1.6 0.54 10.0 0.1 2.1 1 1 0 2 2 2 2 SurA N-terminal domain DUF853 PF05872.12 EAN30794.1 - 0.028 13.0 0.1 0.34 9.5 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) SPARC_Ca_bdg PF10591.9 EAN30794.1 - 0.041 14.2 0.1 9.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 EAN30794.1 - 0.046 14.1 0.3 5.7 7.4 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain zf-CW PF07496.15 EAN30795.1 - 4e-17 62.0 7.1 1e-16 60.6 7.1 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger DUF1878 PF08963.10 EAN30796.1 - 0.45 11.0 4.8 0.13 12.7 1.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) AARP2CN PF08142.12 EAN30797.1 - 3e-22 78.5 1.0 1.1e-21 76.7 0.0 2.5 3 0 0 3 3 3 1 AARP2CN (NUC121) domain RIBIOP_C PF04950.12 EAN30797.1 - 2.5e-08 33.7 0.2 4.9e-08 32.7 0.2 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal GTP_EFTU PF00009.27 EAN30797.1 - 0.00012 21.7 2.7 0.00022 20.8 0.1 2.5 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 EAN30797.1 - 0.009 16.0 0.1 0.009 16.0 0.1 2.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EAN30797.1 - 0.017 15.5 0.2 0.14 12.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 EAN30797.1 - 0.04 14.0 0.3 0.16 12.1 0.3 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EAN30797.1 - 0.05 14.0 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EAN30797.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RIBIOP_C PF04950.12 EAN30798.1 - 5e-43 147.6 0.1 5e-43 147.6 0.1 2.1 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Sugar_tr PF00083.24 EAN30799.1 - 7.8e-66 222.8 28.9 9.6e-66 222.5 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAN30799.1 - 5.4e-19 68.3 26.0 5.4e-19 68.3 26.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TM231 PF10149.9 EAN30799.1 - 0.83 8.9 6.3 1 8.7 0.5 2.9 3 0 0 3 3 3 0 Transmembrane protein 231 Sugar_tr PF00083.24 EAN30800.1 - 8.9e-67 225.9 29.0 1.2e-66 225.5 29.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAN30800.1 - 3.3e-19 69.0 27.4 3.3e-19 69.0 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1335 PF07056.11 EAN30800.1 - 0.061 13.4 0.3 0.34 11.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1335) PhoU PF01895.19 EAN30800.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoU domain DUF2407_C PF13373.6 EAN30800.1 - 1.5 9.0 5.3 0.38 10.9 0.8 2.2 2 0 0 2 2 2 0 DUF2407 C-terminal domain TM231 PF10149.9 EAN30800.1 - 2.7 7.3 7.2 3.1 7.1 0.7 2.9 3 0 0 3 3 3 0 Transmembrane protein 231 tRNA-synt_1e PF01406.19 EAN30801.1 - 1.1e-119 399.3 0.5 1.1e-119 399.3 0.5 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EAN30801.1 - 2.8e-08 32.9 0.7 0.0043 15.8 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EAN30801.1 - 0.00069 18.0 0.2 0.0021 16.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 EAN30801.1 - 0.097 11.6 1.5 0.15 10.9 0.0 2.1 2 1 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain RAP PF08373.10 EAN30802.1 - 1.8e-05 24.7 0.9 4.5e-05 23.5 0.9 1.7 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.15 EAN30802.1 - 0.047 13.6 0.6 2.2 8.3 0.1 3.7 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 zf-CCHC_4 PF14392.6 EAN30802.1 - 0.21 11.4 1.9 0.27 11.0 0.1 2.0 2 0 0 2 2 2 0 Zinc knuckle Alba PF01918.21 EAN30803.1 - 3.2e-08 33.3 0.3 4.1e-08 32.9 0.3 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 EAN30803.1 - 0.01 15.8 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Ycf70 PF17382.2 EAN30804.1 - 0.049 14.0 0.0 0.049 14.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized Ycf70-like NOT2_3_5 PF04153.18 EAN30805.1 - 5.9e-29 100.8 0.8 8.3e-29 100.3 0.8 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family IMP2_N PF18590.1 EAN30806.1 - 2e-27 95.5 0.5 3.5e-27 94.8 0.5 1.4 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain 4HBT PF03061.22 EAN30808.1 - 2.7e-06 27.6 0.1 5.7e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EAN30808.1 - 0.014 15.6 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 EAN30808.1 - 0.025 14.8 0.3 0.46 10.7 0.0 2.0 1 1 1 2 2 2 0 Thioesterase-like superfamily Pet191_N PF10203.9 EAN30811.1 - 0.12 12.7 3.7 0.32 11.3 3.7 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 EAN30811.1 - 0.13 12.4 4.6 1.4 9.1 4.6 2.4 1 1 0 1 1 1 0 CHCH domain UPF0203 PF05254.12 EAN30811.1 - 0.14 12.4 5.3 0.59 10.4 4.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) DUF536 PF04394.14 EAN30811.1 - 0.41 10.5 12.1 0.096 12.6 3.7 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF536 CS PF04969.16 EAN30812.1 - 1e-10 42.4 4.7 2.4e-10 41.3 4.7 1.6 1 1 0 1 1 1 1 CS domain DUF5343 PF17278.2 EAN30812.1 - 0.025 14.7 0.1 0.033 14.3 0.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5343) DUF3449 PF11931.8 EAN30813.1 - 1.4e-69 233.6 0.3 1.4e-69 233.6 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EAN30813.1 - 6.2e-20 71.5 1.2 6.2e-20 71.5 1.2 2.8 3 1 0 3 3 3 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EAN30813.1 - 0.0056 16.5 0.0 0.023 14.6 0.0 2.1 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 EAN30813.1 - 0.044 14.2 0.3 5.6 7.5 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2175 PF09943.9 EAN30813.1 - 0.37 11.1 5.7 12 6.2 1.0 3.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Pneumovirus_M2 PF06436.11 EAN30813.1 - 0.71 9.3 5.0 0.31 10.5 2.2 1.8 2 0 0 2 2 2 0 Pneumovirus matrix protein 2 (M2) Fumerase PF05681.14 EAN30814.1 - 2e-80 270.1 0.0 2.6e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 EAN30814.1 - 1.1e-79 266.5 0.0 1.7e-79 266.0 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus FAINT PF04385.15 EAN30816.1 - 0.0034 17.4 1.3 0.53 10.4 0.2 2.9 3 1 0 3 3 3 2 Domain of unknown function, DUF529 G-patch_2 PF12656.7 EAN30819.1 - 4.2e-17 62.0 0.2 1.7e-16 60.1 0.2 2.1 1 0 0 1 1 1 1 G-patch domain GCS PF03074.16 EAN30820.1 - 5.1e-86 289.3 0.2 2.9e-48 165.1 0.1 2.3 2 0 0 2 2 2 2 Glutamate-cysteine ligase Hormone_4 PF00220.17 EAN30820.1 - 0.36 10.9 1.4 1.2 9.3 1.4 1.9 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain DUF572 PF04502.13 EAN30821.1 - 7.2e-51 173.8 6.9 8.6e-51 173.5 6.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) TF_Zn_Ribbon PF08271.12 EAN30821.1 - 0.045 13.3 0.4 0.045 13.3 0.4 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding TarH PF02203.15 EAN30821.1 - 0.13 12.2 3.4 0.13 12.1 1.4 1.7 1 1 1 2 2 2 0 Tar ligand binding domain homologue zf-FCS PF06467.14 EAN30821.1 - 0.16 11.9 2.3 7.3 6.6 0.1 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Rubredoxin_2 PF18073.1 EAN30821.1 - 0.37 10.6 4.9 0.23 11.2 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain FAINT PF04385.15 EAN30822.1 - 3.5e-20 71.8 60.5 5.8e-06 26.3 8.8 6.6 6 0 0 6 6 6 6 Domain of unknown function, DUF529 PAPS_reduct PF01507.19 EAN30823.1 - 1.6e-21 77.1 0.0 1.5e-13 51.1 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.22 EAN30824.1 - 8.9e-18 63.9 0.1 2.4e-17 62.5 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EAN30824.1 - 0.1 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 RL domain CKS PF01111.19 EAN30825.1 - 4.8e-20 71.6 1.5 7.5e-20 71.0 1.5 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Flavodoxin_1 PF00258.25 EAN30827.1 - 2.5e-21 76.4 0.1 3.8e-21 75.8 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 EAN30827.1 - 5.5e-09 35.9 1.3 1.1e-08 35.0 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EAN30827.1 - 1.9e-06 28.5 0.0 1e-05 26.1 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain YozE_SAM_like PF06855.12 EAN30827.1 - 0.059 13.6 0.0 0.31 11.3 0.0 2.2 1 0 0 1 1 1 0 YozE SAM-like fold PAD_M PF08527.10 EAN30827.1 - 0.069 12.8 0.3 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain AP2 PF00847.20 EAN30828.1 - 5.8e-11 42.5 1.4 1.3e-10 41.3 1.4 1.6 1 0 0 1 1 1 1 AP2 domain Filamin PF00630.19 EAN30829.1 - 0.00025 21.8 0.0 0.00068 20.4 0.0 1.6 2 0 0 2 2 2 1 Filamin/ABP280 repeat RcsC PF09456.10 EAN30829.1 - 0.096 12.7 0.2 18 5.4 0.1 2.2 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) SKA2 PF16740.5 EAN30830.1 - 0.00025 20.8 6.8 0.0011 18.7 0.3 3.0 3 0 0 3 3 3 1 Spindle and kinetochore-associated protein 2 DUF5082 PF16888.5 EAN30830.1 - 0.0012 19.1 1.1 0.0012 19.1 1.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF5082) Spectrin PF00435.21 EAN30830.1 - 0.002 18.6 7.3 0.041 14.4 0.6 2.7 3 0 0 3 3 3 2 Spectrin repeat DUF1877 PF08974.10 EAN30830.1 - 0.018 15.1 2.4 0.018 15.1 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) DivIC PF04977.15 EAN30830.1 - 0.026 14.3 2.7 0.026 14.3 2.7 2.9 3 0 0 3 3 3 0 Septum formation initiator FapA PF03961.13 EAN30830.1 - 0.046 12.3 9.1 0.051 12.2 7.7 1.8 1 1 0 1 1 1 0 Flagellar Assembly Protein A Osmo_CC PF08946.10 EAN30830.1 - 0.064 13.5 4.0 0.2 11.9 4.0 1.8 1 0 0 1 1 1 0 Osmosensory transporter coiled coil TelA PF05816.11 EAN30830.1 - 0.08 12.0 12.0 0.036 13.1 9.1 1.8 2 1 0 2 2 2 0 Toxic anion resistance protein (TelA) DUF4407 PF14362.6 EAN30830.1 - 0.26 10.6 3.4 0.35 10.2 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EAN30830.1 - 0.65 10.3 10.7 0.22 11.8 5.7 2.1 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.22 EAN30830.1 - 1.7 8.9 9.5 2.1 8.6 3.9 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 EAN30830.1 - 2.1 8.6 8.2 13 6.2 2.0 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain Laminin_II PF06009.12 EAN30830.1 - 2.2 8.3 10.8 2.1 8.4 0.8 3.1 2 1 1 3 3 3 0 Laminin Domain II Occludin_ELL PF07303.13 EAN30830.1 - 2.3 9.0 11.4 0.97 10.2 4.4 2.9 2 1 0 3 3 3 0 Occludin homology domain GIT_CC PF16559.5 EAN30830.1 - 3.4 7.6 16.4 0.2 11.5 1.7 3.3 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 EAN30830.1 - 3.5 8.3 13.6 5.7 7.6 3.6 2.9 2 1 1 3 3 3 0 Initiation control protein YabA CENP-H PF05837.12 EAN30830.1 - 6.6 7.2 11.2 3.3 8.1 6.4 2.6 2 1 1 3 3 3 0 Centromere protein H (CENP-H) CRAL_TRIO_2 PF13716.6 EAN30831.1 - 5.2e-06 26.7 0.2 7.1e-06 26.2 0.2 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EAN30832.1 - 1.2e-13 51.5 2.0 3e-13 50.1 2.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 EAN30832.1 - 2.4e-09 37.2 1.9 2.5e-09 37.1 0.3 1.8 2 0 0 2 2 2 1 RhoGAP domain RIH_assoc PF08454.11 EAN30832.1 - 0.017 14.9 8.3 0.041 13.7 4.6 2.7 2 1 1 3 3 3 0 RyR and IP3R Homology associated PRD PF00874.20 EAN30832.1 - 0.026 14.8 1.8 2.3 8.6 0.1 2.4 2 0 0 2 2 2 0 PRD domain Presenilin PF01080.17 EAN30832.1 - 0.35 9.6 10.8 0.62 8.8 10.8 1.3 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EAN30832.1 - 1.3 8.1 4.4 2.1 7.5 4.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAINT PF04385.15 EAN30834.1 - 0.00035 20.6 3.6 0.062 13.4 2.9 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DJ-1_PfpI PF01965.24 EAN30835.1 - 2e-29 102.5 0.2 2.4e-29 102.3 0.2 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF2053 PF09767.9 EAN30836.1 - 3.5e-11 43.5 6.2 1.6e-07 31.6 2.2 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2053) zf-RING_2 PF13639.6 EAN30837.1 - 1e-11 44.9 4.5 2.5e-11 43.7 4.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAN30837.1 - 1.1e-09 37.9 3.7 2.5e-09 36.8 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAN30837.1 - 8.5e-09 35.6 2.6 2.3e-08 34.2 2.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EAN30837.1 - 1.9e-07 30.8 3.3 3.8e-07 29.8 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN30837.1 - 1.3e-06 28.3 2.0 3.1e-06 27.1 2.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAN30837.1 - 6.5e-06 26.0 3.9 1.4e-05 24.9 3.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EAN30837.1 - 1.2e-05 25.1 4.1 3.9e-05 23.4 4.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EAN30837.1 - 0.00022 21.2 0.5 0.00054 20.0 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EAN30837.1 - 0.0011 18.7 1.4 0.0027 17.4 1.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EAN30837.1 - 0.003 17.1 3.0 0.003 17.1 3.0 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EAN30837.1 - 0.0061 16.4 4.6 0.016 15.1 4.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zf_RING PF16744.5 EAN30837.1 - 0.11 12.6 2.5 0.32 11.2 2.5 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger FANCL_C PF11793.8 EAN30837.1 - 0.12 12.6 6.2 1.9 8.8 6.2 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.11 EAN30837.1 - 0.14 12.2 0.8 1.3 9.0 0.0 2.6 3 0 0 3 3 2 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.6 EAN30837.1 - 0.53 10.5 5.1 1.5 9.1 5.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EAN30837.1 - 0.55 10.1 2.6 1.9 8.3 2.6 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EAN30837.1 - 1.1 9.4 7.6 0.23 11.6 3.2 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING-like PF08746.11 EAN30837.1 - 1.9 8.9 4.1 4.9 7.6 4.1 1.7 1 0 0 1 1 1 0 RING-like domain zf-P11 PF03854.14 EAN30837.1 - 2.6 7.8 7.4 2.1 8.1 1.8 2.5 1 1 0 2 2 2 0 P-11 zinc finger Ribosomal_L18p PF00861.22 EAN30841.1 - 1.1e-20 74.1 0.4 8.2e-20 71.3 0.4 1.9 1 1 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast FAST_1 PF06743.15 EAN30842.1 - 0.011 15.6 0.3 5.7 7.0 0.0 3.8 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 DUF4806 PF16064.5 EAN30842.1 - 3 8.2 7.0 6 7.2 1.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) Sec1 PF00995.23 EAN30843.1 - 4.2e-91 306.9 8.1 6.2e-91 306.4 8.1 1.2 1 0 0 1 1 1 1 Sec1 family EIF4E-T PF10477.9 EAN30843.1 - 0.033 13.0 0.4 0.044 12.6 0.4 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DPPIV_rep PF18811.1 EAN30843.1 - 0.081 12.9 0.2 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region CelTOS PF18659.1 EAN30843.1 - 0.3 11.5 1.6 23 5.4 0.2 3.0 3 0 0 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites LMF1 PF06762.14 EAN30844.1 - 4.1e-117 392.0 14.1 4.1e-117 392.0 14.1 1.7 2 0 0 2 2 2 1 Lipase maturation factor Pyr_redox_2 PF07992.14 EAN30845.1 - 3.3e-42 144.7 0.0 3.7e-41 141.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EAN30845.1 - 9.4e-22 77.4 0.0 2.5e-21 76.0 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EAN30845.1 - 9.5e-16 58.1 3.2 5.4e-12 46.1 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAN30845.1 - 5.9e-07 28.9 1.6 4.9e-05 22.6 0.2 2.3 1 1 1 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EAN30845.1 - 7.3e-07 28.9 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAN30845.1 - 7.4e-07 28.6 0.0 1.4e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EAN30845.1 - 1.6e-06 27.7 0.2 0.0093 15.2 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EAN30845.1 - 6.3e-06 25.6 0.0 0.0018 17.6 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EAN30845.1 - 5.6e-05 22.0 0.1 0.00013 20.9 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EAN30845.1 - 0.0011 19.2 2.8 0.0057 16.8 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAN30845.1 - 0.0042 16.7 0.9 0.033 13.8 0.3 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Caudo_bapla_RBP PF08931.10 EAN30845.1 - 0.0064 16.0 0.0 0.022 14.2 0.0 1.8 2 0 0 2 2 2 1 Receptor-binding protein of phage tail base-plate Siphoviridae, head K_oxygenase PF13434.6 EAN30845.1 - 0.015 14.4 0.0 0.059 12.5 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EAN30845.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 EAN30845.1 - 0.058 12.6 0.3 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Cnd2 PF05786.14 EAN30846.1 - 1.2e-17 63.9 7.0 3.3e-12 45.9 4.6 3.1 2 1 0 2 2 2 2 Condensin complex subunit 2 CNDH2_N PF06278.11 EAN30846.1 - 0.0009 19.4 0.2 0.0025 18.0 0.2 1.7 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CPT_N PF16484.5 EAN30846.1 - 0.14 12.2 0.0 0.49 10.4 0.0 1.9 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus FANCI_S2 PF14676.6 EAN30847.1 - 1 9.6 7.9 0.5 10.7 1.3 2.9 2 1 0 2 2 2 0 FANCI solenoid 2 DUF4523 PF15023.6 EAN30847.1 - 5.3 6.8 12.0 3.3 7.5 5.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) FAINT PF04385.15 EAN30849.1 - 2.5e-79 261.3 122.6 3.4e-11 43.0 4.3 16.2 15 1 1 16 16 16 15 Domain of unknown function, DUF529 PS_Dcarbxylase PF02666.15 EAN30849.1 - 0.0011 18.6 0.0 0.0027 17.3 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Tfb5 PF06331.12 EAN30850.1 - 3e-09 36.7 0.3 3.1e-09 36.7 0.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 SRA1 PF07304.11 EAN30850.1 - 0.14 12.0 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Beta-lactamase PF00144.24 EAN30850.1 - 0.21 10.8 0.0 0.21 10.8 0.0 1.0 1 0 0 1 1 1 0 Beta-lactamase Arf PF00025.21 EAN30851.1 - 5.1e-05 22.8 0.0 5.5e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Arf PF00025.21 EAN30852.1 - 3.4e-55 186.2 4.0 3.7e-55 186.1 4.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAN30852.1 - 3.5e-14 53.1 0.6 4.7e-14 52.6 0.6 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EAN30852.1 - 1.6e-11 44.0 0.6 1.9e-11 43.8 0.6 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EAN30852.1 - 1.4e-10 41.0 0.9 1.5e-10 40.9 0.9 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EAN30852.1 - 1.5e-10 40.8 8.0 3.1e-06 26.6 3.3 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EAN30852.1 - 1.1e-08 34.8 0.2 1.3e-08 34.5 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAN30852.1 - 9.6e-08 32.1 0.2 1.5e-07 31.5 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EAN30852.1 - 0.0026 18.3 0.1 0.0043 17.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EAN30852.1 - 0.0042 16.7 0.6 0.11 12.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EAN30852.1 - 0.026 14.9 0.0 0.034 14.6 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EAN30852.1 - 0.054 13.5 0.5 0.12 12.4 0.5 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAN30852.1 - 0.071 13.6 1.0 0.099 13.2 1.0 1.5 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 EAN30852.1 - 0.11 12.2 0.1 0.83 9.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain T_cell_tran_alt PF15128.6 EAN30853.1 - 0.018 14.8 0.5 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF1098 PF06497.11 EAN30854.1 - 0.047 14.2 0.2 0.097 13.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) Mononeg_mRNAcap PF14318.6 EAN30854.1 - 0.8 8.9 5.7 0.31 10.3 2.8 1.7 1 1 1 2 2 2 0 Mononegavirales mRNA-capping region V zf-HIT PF04438.16 EAN30856.1 - 0.012 15.4 11.8 0.012 15.4 11.8 1.9 3 0 0 3 3 3 0 HIT zinc finger DUF5395 PF17373.2 EAN30856.1 - 0.069 13.8 0.1 0.21 12.2 0.1 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5395) CBF PF03914.17 EAN30857.1 - 0.42 10.6 5.3 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 CBF/Mak21 family SWC7 PF17330.2 EAN30858.1 - 0.042 13.9 0.4 0.042 13.9 0.4 2.2 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Transket_pyr PF02779.24 EAN30859.1 - 2.4e-48 164.2 0.0 3.4e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EAN30859.1 - 6.5e-41 139.6 0.0 1.1e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EAN30859.1 - 6.1e-38 130.5 0.1 9.7e-38 129.8 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 EAN30859.1 - 3.9e-06 26.3 0.8 3.9e-06 26.3 0.8 2.1 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus YHYH PF14240.6 EAN30859.1 - 0.092 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 YHYH protein HTH_22 PF13309.6 EAN30859.1 - 0.15 12.1 0.0 0.45 10.6 0.0 1.8 1 0 0 1 1 1 0 HTH domain Sec3-PIP2_bind PF15277.6 EAN30860.1 - 0.033 14.3 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH TFIIS_M PF07500.14 EAN30861.1 - 3.5e-14 53.2 1.1 3.5e-14 53.2 1.1 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Phage_term_sma PF07141.11 EAN30861.1 - 0.2 11.4 3.7 9 6.0 0.7 2.4 2 1 0 2 2 2 0 Putative bacteriophage terminase small subunit pRN1_helical PF13010.6 EAN30862.1 - 0.049 13.6 1.8 0.052 13.5 0.5 1.6 1 1 1 2 2 2 0 Primase helical domain SNF2_N PF00176.23 EAN30863.1 - 3.7e-35 121.3 0.2 1.4e-34 119.4 0.2 1.9 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAN30863.1 - 1.8e-20 73.4 0.4 1.1e-19 70.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain QLQ PF08880.11 EAN30863.1 - 0.032 14.0 0.6 0.067 13.0 0.6 1.5 1 0 0 1 1 1 0 QLQ APG12 PF04110.13 EAN30863.1 - 2.4 8.6 8.1 1.2 9.6 0.3 3.7 3 1 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 CRAL_TRIO PF00650.20 EAN30864.1 - 2.8e-36 124.6 0.3 4.3e-36 124.0 0.3 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EAN30864.1 - 4.6e-07 30.1 0.1 8e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain LisH PF08513.11 EAN30864.1 - 0.056 13.4 1.3 0.11 12.5 1.3 1.5 1 0 0 1 1 1 0 LisH Evr1_Alr PF04777.13 EAN30865.1 - 5.1e-09 36.5 0.3 7e-09 36.1 0.3 1.2 1 0 0 1 1 1 1 Erv1 / Alr family MMR_HSR1 PF01926.23 EAN30866.1 - 2.6e-11 43.6 0.1 6.3e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAN30866.1 - 8.4e-07 28.7 0.6 0.00014 21.5 0.5 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAN30866.1 - 4.2e-06 26.8 1.2 0.01 15.7 0.6 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EAN30866.1 - 0.00017 21.7 5.7 0.0026 17.9 0.2 2.9 2 1 1 3 3 3 2 Dynamin family RNA_helicase PF00910.22 EAN30866.1 - 0.051 14.0 0.0 0.28 11.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 EAN30866.1 - 0.076 12.6 0.8 4.7 6.8 0.1 2.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EAN30866.1 - 0.087 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EAN30866.1 - 0.16 12.4 6.8 0.96 9.9 6.3 2.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 EAN30866.1 - 0.3 11.1 4.5 0.25 11.4 2.3 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain XhlA PF10779.9 EAN30866.1 - 0.68 10.2 3.8 0.69 10.2 1.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Spc7 PF08317.11 EAN30871.1 - 0.13 11.1 5.4 0.15 10.9 5.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF702 PF05142.12 EAN30871.1 - 0.18 12.3 0.2 0.25 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) tRNA-synt_1g PF09334.11 EAN30872.1 - 8.1e-82 275.0 4.5 4.1e-38 131.1 0.7 3.2 2 1 1 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EAN30872.1 - 3.9e-39 134.4 5.4 6.1e-23 80.9 0.5 3.9 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EAN30872.1 - 1.3e-15 57.5 3.5 2.5e-07 30.4 0.1 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EAN30872.1 - 3.2e-05 23.0 0.0 0.0053 15.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 EAN30872.1 - 0.00047 20.2 0.1 0.0012 18.9 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.19 EAN30872.1 - 0.014 14.3 0.1 2.6 6.9 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (R) DUF5531 PF17671.1 EAN30872.1 - 0.082 12.8 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5531) DUF547 PF04784.14 EAN30873.1 - 0.04 14.0 0.1 0.085 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF547 BLOC1_2 PF10046.9 EAN30873.1 - 0.12 12.6 8.3 4.4 7.7 6.1 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 QueF_N PF14819.6 EAN30873.1 - 0.15 12.4 1.6 3.6 8.0 0.5 2.4 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term HSBP1 PF06825.12 EAN30873.1 - 0.24 11.3 6.7 2.7 7.9 0.2 3.1 3 1 1 4 4 4 0 Heat shock factor binding protein 1 FAM76 PF16046.5 EAN30873.1 - 0.37 10.1 4.9 0.49 9.7 4.9 1.3 1 0 0 1 1 1 0 FAM76 protein CCDC-167 PF15188.6 EAN30873.1 - 2.7 8.4 9.8 2.7 8.4 4.1 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Fib_alpha PF08702.10 EAN30873.1 - 4.5 7.5 12.6 1.5 9.0 5.8 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF1690 PF07956.11 EAN30873.1 - 6.1 7.3 9.6 2.9 8.3 1.8 2.5 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Pkinase PF00069.25 EAN30875.1 - 6.9e-61 205.9 0.0 3.7e-45 154.4 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAN30875.1 - 1.9e-26 92.9 0.0 4e-16 59.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EAN30875.1 - 0.00015 20.8 0.2 0.013 14.5 0.0 2.3 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 EAN30875.1 - 0.1 12.5 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Presenilin PF01080.17 EAN30875.1 - 0.3 9.8 0.5 0.43 9.3 0.5 1.2 1 0 0 1 1 1 0 Presenilin Arm PF00514.23 EAN30876.1 - 0.00039 20.4 0.0 0.14 12.3 0.0 3.0 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat ArsA_ATPase PF02374.15 EAN30877.1 - 3.8e-87 292.3 3.8 3.1e-80 269.6 0.4 2.1 1 1 1 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 EAN30877.1 - 2.5e-11 43.7 0.6 1.9e-10 40.9 0.6 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EAN30877.1 - 1.9e-10 41.0 0.3 3.8e-09 36.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 EAN30877.1 - 8.6e-06 25.4 0.0 4.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 EAN30877.1 - 1e-05 25.1 0.1 0.00051 19.6 0.0 2.2 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EAN30877.1 - 0.00028 20.4 0.0 0.00053 19.5 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EAN30877.1 - 0.00079 19.1 0.0 0.027 14.1 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 EAN30877.1 - 0.0034 16.6 0.0 0.0069 15.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain PIF1 PF05970.14 EAN30877.1 - 0.0056 15.9 0.1 0.03 13.5 0.0 2.1 2 1 1 3 3 3 1 PIF1-like helicase Zeta_toxin PF06414.12 EAN30877.1 - 0.0093 15.3 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin ATP_bind_1 PF03029.17 EAN30877.1 - 0.018 14.9 0.2 0.073 12.8 0.0 2.1 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EAN30877.1 - 0.043 14.4 0.1 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EAN30877.1 - 0.078 12.9 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 EAN30877.1 - 0.081 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.11 EAN30877.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 VirC1 protein AAA_25 PF13481.6 EAN30877.1 - 0.19 11.3 0.1 0.72 9.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF1611 PF07755.11 EAN30877.1 - 0.22 10.7 0.0 0.46 9.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain Nod1 PF17114.5 EAN30877.1 - 1.5 9.0 7.7 0.36 11.0 0.5 3.0 2 1 1 3 3 3 0 Gef2-related medial cortical node protein Nod1 Aquarius_N PF16399.5 EAN30879.1 - 3.5e-68 230.4 36.6 3.7e-40 137.8 13.3 4.0 2 2 0 2 2 2 2 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 EAN30879.1 - 2.3e-27 96.4 0.0 1.2e-26 94.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EAN30879.1 - 7.6e-27 94.2 0.0 7.6e-27 94.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EAN30879.1 - 9.2e-06 26.1 0.0 5.7e-05 23.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAN30879.1 - 0.0021 17.8 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EAN30879.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EAN30879.1 - 0.0057 16.4 0.0 4.9 6.8 0.0 3.8 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EAN30879.1 - 0.019 15.3 0.6 3.7 8.0 0.0 3.9 4 0 0 4 4 3 0 RNA helicase AAA_22 PF13401.6 EAN30879.1 - 0.062 13.6 0.0 0.38 11.0 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAN30879.1 - 0.072 13.5 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 EAN30879.1 - 0.078 13.0 0.6 1.1 9.2 0.0 3.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.29 EAN30879.1 - 0.11 12.9 0.0 0.45 10.9 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EAN30879.1 - 0.19 11.1 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EAN30879.1 - 0.24 11.0 0.0 0.44 10.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Synaptobrevin PF00957.21 EAN30880.1 - 4.6e-09 36.0 0.6 8.3e-09 35.1 0.6 1.4 1 0 0 1 1 1 1 Synaptobrevin tRNA-synt_1f PF01921.18 EAN30880.1 - 0.053 12.4 0.1 0.068 12.1 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) Longin PF13774.6 EAN30880.1 - 0.059 13.4 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain Adaptin_N PF01602.20 EAN30881.1 - 9.6e-49 166.3 12.3 4.2e-48 164.2 12.3 1.8 1 1 0 1 1 1 1 Adaptin N terminal region MIF4G PF02854.19 EAN30881.1 - 0.03 14.0 0.5 0.03 14.0 0.5 2.7 3 0 0 3 3 3 0 MIF4G domain FUSC PF04632.12 EAN30882.1 - 0.68 8.4 3.5 1.4 7.4 3.5 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF501 PF04417.12 EAN30882.1 - 7 6.5 11.9 0.82 9.5 5.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF501) FAINT PF04385.15 EAN30883.1 - 7.1e-30 102.9 28.7 5.2e-06 26.4 1.6 10.2 10 0 0 10 10 10 8 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30884.1 - 3.2e-05 23.9 1.9 3.2e-05 23.9 1.9 5.3 5 1 0 5 5 5 2 Domain of unknown function, DUF529 AMIN PF11741.8 EAN30884.1 - 0.0034 17.5 0.1 0.0083 16.2 0.1 1.6 1 0 0 1 1 1 1 AMIN domain CUB_2 PF02408.20 EAN30884.1 - 0.11 12.3 1.0 0.31 10.8 0.1 2.3 3 0 0 3 3 3 0 CUB-like domain RRM_3 PF08777.11 EAN30885.1 - 0.0035 17.4 0.0 0.0043 17.1 0.0 1.1 1 0 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 EAN30885.1 - 0.0058 16.4 0.1 0.0099 15.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_12 PF17901.1 EAN30885.1 - 0.13 12.8 0.1 3.8 8.0 0.1 2.1 2 0 0 2 2 2 0 EF-hand fold domain Histone PF00125.24 EAN30887.1 - 2.9e-51 173.3 1.7 3.2e-51 173.1 1.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EAN30887.1 - 3.7e-05 24.0 0.0 5.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EAN30887.1 - 0.00022 21.8 0.8 0.00026 21.6 0.8 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EAN30887.1 - 0.00041 20.4 0.5 0.00061 19.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EAN30887.1 - 0.028 14.7 0.8 0.043 14.1 0.0 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EAN30887.1 - 0.034 14.2 0.2 0.059 13.4 0.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Defensin_4 PF07936.12 EAN30888.1 - 0.17 11.8 1.6 0.58 10.1 1.6 1.9 1 0 0 1 1 1 0 Potassium-channel blocking toxin eIF3_subunit PF08597.10 EAN30890.1 - 3.1e-13 50.2 11.1 4e-13 49.8 11.1 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit GWT1 PF06423.12 EAN30892.1 - 3.2e-14 53.3 10.3 3.2e-14 53.3 10.3 2.4 2 0 0 2 2 2 1 GWT1 PDZ_3 PF17815.1 EAN30893.1 - 0.016 15.1 0.3 0.039 13.8 0.3 1.6 1 0 0 1 1 1 0 PDZ domain CelD_N PF02927.14 EAN30893.1 - 0.024 15.5 0.6 0.024 15.5 0.6 2.0 2 0 0 2 2 2 0 Cellulase N-terminal ig-like domain AdoHcyase PF05221.17 EAN30895.1 - 8.3e-75 251.7 0.0 1e-74 251.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EAN30895.1 - 1.3e-53 181.4 3.0 2.2e-53 180.7 3.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EAN30895.1 - 1.6e-05 24.3 0.2 3.7e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EAN30895.1 - 0.0011 18.5 0.1 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 EAN30895.1 - 0.0065 15.8 0.9 0.053 12.8 0.9 2.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HhH-GPD PF00730.25 EAN30897.1 - 2.4e-24 85.9 0.2 8.5e-24 84.1 0.0 2.0 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EAN30897.1 - 9e-08 31.6 0.0 3.1e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EAN30897.1 - 0.00012 22.6 1.0 0.17 12.5 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_8 PF14716.6 EAN30897.1 - 0.00054 20.3 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain SAM_KSR1 PF13543.6 EAN30897.1 - 0.03 14.5 0.4 0.03 14.5 0.4 1.9 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Cdd1 PF11731.8 EAN30897.1 - 0.091 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus Ribosomal_L19e PF01280.20 EAN30898.1 - 1.4e-59 200.3 4.9 1.4e-59 200.3 4.9 1.5 1 1 1 2 2 2 1 Ribosomal protein L19e HMw1_D2 PF18254.1 EAN30898.1 - 0.035 14.5 0.3 0.069 13.5 0.3 1.5 1 0 0 1 1 1 0 HMW1 domain 2 Fe_hyd_lg_C PF02906.14 EAN30899.1 - 4.5e-36 124.8 0.0 2.3e-18 66.8 0.0 4.0 2 2 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain ABC_tran PF00005.27 EAN30900.1 - 6.5e-23 81.8 0.0 8.4e-17 62.0 0.0 3.1 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAN30900.1 - 8.1e-11 42.1 15.2 8.1e-11 42.1 15.2 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region RsgA_GTPase PF03193.16 EAN30900.1 - 0.0006 19.8 0.2 0.0014 18.5 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EAN30900.1 - 0.0065 16.2 0.1 0.076 12.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EAN30900.1 - 0.0083 16.2 0.5 0.035 14.2 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 EAN30900.1 - 0.015 15.2 4.0 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 EAN30900.1 - 0.02 15.0 1.7 0.033 14.3 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 EAN30900.1 - 0.026 14.3 0.0 0.026 14.3 0.0 3.9 5 0 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 EAN30900.1 - 0.028 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 EAN30900.1 - 0.078 12.3 0.5 0.36 10.2 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family PPR_2 PF13041.6 EAN30901.1 - 0.13 12.4 0.6 0.6 10.4 0.3 2.0 2 0 0 2 2 2 0 PPR repeat family Ubiquitin_4 PF18036.1 EAN30901.1 - 0.51 10.4 5.3 0.12 12.5 1.3 2.0 2 1 1 3 3 3 0 Ubiquitin-like domain AKAP_110 PF05716.13 EAN30902.1 - 0.15 10.3 0.0 0.19 9.9 0.0 1.0 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) Ac76 PF05814.11 EAN30902.1 - 8.9 6.4 11.1 7.5 6.6 4.4 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) PepSY_like PF11396.8 EAN30903.1 - 1.1 9.8 4.2 13 6.4 0.2 3.9 4 0 0 4 4 4 0 Putative beta-lactamase-inhibitor-like, PepSY-like bZIP_1 PF00170.21 EAN30904.1 - 0.00029 20.9 4.1 0.00029 20.9 4.1 2.9 3 1 0 3 3 3 1 bZIP transcription factor TPR_MLP1_2 PF07926.12 EAN30904.1 - 0.00053 20.1 7.0 0.00063 19.8 1.5 2.3 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein MCC-bdg_PDZ PF10506.9 EAN30904.1 - 0.00053 19.9 0.4 0.00053 19.9 0.4 2.4 3 0 0 3 3 3 1 PDZ domain of MCC-2 bdg protein for Usher syndrome DivIC PF04977.15 EAN30904.1 - 0.027 14.2 0.5 0.099 12.4 0.5 1.9 1 0 0 1 1 1 0 Septum formation initiator Mto2_bdg PF12808.7 EAN30904.1 - 0.12 12.7 0.8 0.12 12.7 0.8 2.1 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region ZapB PF06005.12 EAN30904.1 - 0.27 11.7 7.1 0.2 12.1 3.7 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 EAN30904.1 - 0.35 11.1 5.2 0.13 12.6 1.5 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 RasGAP_C PF03836.15 EAN30904.1 - 0.39 10.9 9.2 0.38 10.9 3.2 3.0 2 2 1 3 3 3 0 RasGAP C-terminus Tropomyosin_1 PF12718.7 EAN30904.1 - 0.5 10.5 12.2 0.26 11.4 4.5 2.3 2 0 0 2 2 2 0 Tropomyosin like bZIP_2 PF07716.15 EAN30904.1 - 0.7 10.0 5.6 2.6 8.2 1.2 2.8 2 0 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.18 EAN30904.1 - 1.1 9.6 8.0 5 7.5 0.4 3.6 4 0 0 4 4 4 0 TSC-22/dip/bun family SecA_DEAD PF07517.14 EAN30905.1 - 0.038 13.3 0.4 0.095 12.0 0.1 1.8 2 0 0 2 2 2 0 SecA DEAD-like domain Beta-Casp PF10996.8 EAN30906.1 - 1.2e-22 80.2 0.0 3.3e-22 78.8 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 EAN30906.1 - 9.1e-19 67.2 0.1 1.7e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 EAN30906.1 - 1.7e-12 47.2 0.0 8.2e-12 45.0 0.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EAN30906.1 - 2e-07 31.2 0.6 0.0079 16.2 0.5 3.2 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAN30906.1 - 0.00043 19.8 0.3 0.012 15.2 0.0 2.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain FtsJ PF01728.19 EAN30907.1 - 3.2e-24 86.0 0.1 4.4e-08 33.4 0.0 4.0 3 1 1 4 4 4 3 FtsJ-like methyltransferase MarR_2 PF12802.7 EAN30908.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 MarR family SWIB PF02201.18 EAN30908.1 - 0.064 13.1 0.4 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 SWIB/MDM2 domain Big_4 PF07532.11 EAN30908.1 - 0.12 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) DUF4492 PF14899.6 EAN30910.1 - 0.00012 21.9 4.7 0.00012 21.9 4.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4492) Peptidase_M56 PF05569.11 EAN30910.1 - 0.0082 15.4 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 BlaR1 peptidase M56 Tetraspanin PF00335.20 EAN30910.1 - 0.018 14.8 0.7 0.034 13.9 0.7 1.4 1 0 0 1 1 1 0 Tetraspanin family CRPA PF05745.11 EAN30910.1 - 0.12 12.4 0.4 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Vpu PF00558.19 EAN30910.1 - 0.18 11.6 3.0 0.34 10.7 0.3 2.4 1 1 1 2 2 2 0 Vpu protein CAP_C PF08603.11 EAN30911.1 - 2.3e-38 131.3 8.5 2.5e-38 131.1 8.5 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EAN30911.1 - 0.058 13.1 7.3 0.18 11.5 7.1 1.7 1 1 0 1 1 1 0 Tubulin binding cofactor C SAP PF02037.27 EAN30913.1 - 5.8e-12 45.1 0.0 1.7e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 SAP domain DUF3581 PF12119.8 EAN30913.1 - 0.0089 15.5 0.1 0.019 14.3 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3581) DAG_kinase_N PF14513.6 EAN30913.1 - 0.1 12.8 4.9 0.13 12.5 4.9 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus RAP1 PF07218.11 EAN30913.1 - 0.77 8.0 13.9 0.8 7.9 13.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 EAN30913.1 - 7.6 5.0 12.8 7.7 4.9 12.8 1.0 1 0 0 1 1 1 0 Macoilin family PhoD PF09423.10 EAN30914.1 - 6.8e-13 48.3 0.0 5.7e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 PhoD-like phosphatase Ank_4 PF13637.6 EAN30915.1 - 1.7e-29 101.8 0.1 5.7e-12 45.9 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAN30915.1 - 3.6e-29 101.2 0.1 1.8e-15 57.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) RNA_GG_bind PF10258.9 EAN30915.1 - 5.6e-24 84.0 0.0 1.5e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 PHAX RNA-binding domain Ank_3 PF13606.6 EAN30915.1 - 5.9e-22 75.4 0.3 7.6e-05 22.8 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAN30915.1 - 7.6e-20 70.7 0.0 2.2e-07 31.0 0.0 4.7 1 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAN30915.1 - 4.8e-19 67.9 0.3 0.00083 19.7 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Noggin PF05806.12 EAN30915.1 - 1.1 9.1 3.9 0.5 10.2 0.1 2.2 2 0 0 2 2 2 0 Noggin FAINT PF04385.15 EAN30916.1 - 2.7e-15 56.2 32.2 4.3e-07 29.9 0.0 5.9 6 1 1 7 7 7 4 Domain of unknown function, DUF529 Retinal PF15449.6 EAN30916.1 - 1.7 6.3 13.5 2.3 5.9 13.5 1.0 1 0 0 1 1 1 0 Retinal protein Cpn60_TCP1 PF00118.24 EAN30918.1 - 1.1e-149 499.3 3.3 1.2e-149 499.1 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CDC50 PF03381.15 EAN30919.1 - 6.3e-22 78.4 4.3 1.6e-20 73.8 3.1 2.6 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RNA_pol_Rpb1_5 PF04998.17 EAN30920.1 - 1.1e-99 333.2 0.1 2e-99 332.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EAN30920.1 - 2.4e-98 329.3 0.4 2.4e-98 329.3 0.4 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EAN30920.1 - 3.7e-73 245.2 0.0 6.8e-73 244.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EAN30920.1 - 1.4e-49 168.6 0.7 2.7e-49 167.6 0.4 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EAN30920.1 - 4.8e-46 156.5 0.1 1.3e-45 155.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EAN30920.1 - 7e-37 125.7 0.1 1.6e-36 124.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 EAN30920.1 - 3.6e-36 124.1 0.0 7.2e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 Band_7 PF01145.25 EAN30921.1 - 9.6e-28 97.4 2.4 1.1e-27 97.1 0.0 2.0 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EAN30921.1 - 4.5e-16 58.6 3.5 6.2e-16 58.2 1.0 2.3 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 EAN30921.1 - 0.012 15.3 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF262 PF03235.14 EAN30921.1 - 0.16 12.1 2.4 0.23 11.6 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF1151 PF06625.11 EAN30921.1 - 0.31 11.0 3.3 0.54 10.2 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Phi-29_GP16_7 PF06720.11 EAN30922.1 - 0.065 13.1 0.6 0.11 12.3 0.6 1.4 1 1 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 Ribosomal_L18 PF17135.4 EAN30924.1 - 0.08 12.3 1.0 0.1 12.0 1.0 1.1 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L21p PF00829.21 EAN30926.1 - 4.6e-23 81.4 0.0 6.7e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein GTP_EFTU PF00009.27 EAN30927.1 - 3.3e-31 108.4 2.2 1.1e-29 103.4 2.2 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EAN30927.1 - 3.9e-09 36.6 1.2 2.6e-05 24.3 0.3 3.6 2 1 0 3 3 3 2 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EAN30927.1 - 1.4e-08 34.8 0.4 9.2e-08 32.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EAN30927.1 - 0.00016 21.5 0.2 0.0041 16.9 0.2 2.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EAN30927.1 - 0.00017 21.5 0.8 0.056 13.4 0.1 3.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EAN30927.1 - 0.0011 19.0 0.9 0.0051 16.8 0.1 2.7 3 0 0 3 3 3 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 EAN30927.1 - 0.017 15.2 2.1 0.083 12.9 0.1 3.2 2 1 0 2 2 2 0 Dynamin family FliG_M PF14841.6 EAN30927.1 - 0.13 12.5 0.2 15 5.9 0.0 3.1 3 0 0 3 3 3 0 FliG middle domain FAINT PF04385.15 EAN30928.1 - 5.5e-05 23.2 0.1 5.5e-05 23.2 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function, DUF529 E7 PF00527.18 EAN30928.1 - 0.099 12.8 3.4 1.6 9.0 0.2 2.8 3 0 0 3 3 3 0 E7 protein, Early protein FAINT PF04385.15 EAN30929.1 - 0.00076 19.5 0.0 0.00076 19.5 0.0 3.2 4 0 0 4 4 4 2 Domain of unknown function, DUF529 UPF0515 PF15135.6 EAN30929.1 - 0.024 14.0 0.9 0.024 14.0 0.9 1.7 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 Zn-ribbon_8 PF09723.10 EAN30929.1 - 2.5 8.3 6.2 0.96 9.6 2.6 2.0 2 0 0 2 2 2 0 Zinc ribbon domain DEAD PF00270.29 EAN30930.1 - 2.6e-43 147.8 0.0 6.5e-43 146.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN30930.1 - 3.8e-27 94.8 0.9 1.9e-26 92.6 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EAN30930.1 - 0.076 13.3 0.0 5.9 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain FAINT PF04385.15 EAN30931.1 - 7.5e-08 32.3 3.1 2.1e-06 27.7 2.9 5.8 4 3 1 5 5 5 3 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30932.1 - 1.3e-28 98.9 21.6 4.4e-13 49.1 1.2 5.6 5 0 0 5 5 5 4 Domain of unknown function, DUF529 BRCT PF00533.26 EAN30932.1 - 0.003 17.9 4.2 1.1 9.7 0.0 3.6 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RNA_pol_A_bac PF01000.26 EAN30934.1 - 2.9e-05 24.4 0.4 0.0002 21.7 0.0 2.4 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EAN30934.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain FAINT PF04385.15 EAN30935.1 - 2.6e-21 75.5 20.6 2.4e-09 37.1 0.4 5.1 5 1 0 5 5 5 3 Domain of unknown function, DUF529 Hydrolase_4 PF12146.8 EAN30935.1 - 2.6e-21 76.0 0.0 1.6e-14 53.8 0.0 2.8 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAN30935.1 - 3.9e-06 26.7 0.0 0.0013 18.4 0.2 2.6 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAN30935.1 - 0.00043 21.0 0.0 0.0019 18.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EAN30935.1 - 0.00077 19.5 0.0 0.0047 17.0 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein LIDHydrolase PF10230.9 EAN30935.1 - 0.0031 17.1 0.0 0.007 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Pyrid_oxidase_2 PF13883.6 EAN30935.1 - 0.089 12.8 0.9 0.21 11.5 0.9 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase RRM_1 PF00076.22 EAN30936.1 - 5.3e-10 39.0 0.3 0.00055 19.7 0.0 4.8 4 2 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAN30936.1 - 0.023 14.5 0.0 6.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Msg2_C PF12373.8 EAN30936.1 - 0.054 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal DNA_pol_B PF00136.21 EAN30937.1 - 1.2e-98 330.8 4.1 8.7e-97 324.7 4.1 2.4 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EAN30937.1 - 1e-22 80.8 7.6 3.1e-22 79.2 7.6 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EAN30937.1 - 2.2e-10 40.5 6.5 5.1e-10 39.3 6.5 1.7 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal YnfE PF17452.2 EAN30937.1 - 0.017 15.4 0.2 0.068 13.5 0.2 2.0 1 0 0 1 1 1 0 Uncharacterized YnfE-like SPT6_acidic PF14632.6 EAN30937.1 - 0.47 11.1 7.5 1.1 9.9 7.5 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 WD40 PF00400.32 EAN30938.1 - 1.3e-20 73.3 12.4 2.1e-05 25.2 0.1 8.1 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN30938.1 - 2.5e-12 46.9 0.1 0.013 15.8 0.0 5.6 4 1 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAN30938.1 - 0.0056 15.7 0.1 0.25 10.3 0.0 3.0 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EAN30938.1 - 0.071 13.1 1.5 6.2 6.9 0.2 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF3206 PF11472.8 EAN30939.1 - 0.0089 16.0 5.4 0.056 13.4 1.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3206) Thioredoxin PF00085.20 EAN30939.1 - 0.022 14.7 0.0 0.064 13.3 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin NTP_transf_2 PF01909.23 EAN30940.1 - 7.4e-07 29.4 0.0 1.9e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EAN30940.1 - 0.013 15.5 0.1 0.1 12.7 0.0 2.5 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase PAP_assoc PF03828.19 EAN30940.1 - 0.014 15.6 0.2 0.065 13.5 0.2 2.2 1 0 0 1 1 1 0 Cid1 family poly A polymerase Cpn60_TCP1 PF00118.24 EAN30941.1 - 2e-80 270.8 2.7 8.5e-80 268.7 2.7 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FMO-like PF00743.19 EAN30941.1 - 0.038 12.4 0.3 0.17 10.2 0.1 1.9 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like DUF572 PF04502.13 EAN30943.1 - 4e-40 138.5 16.0 1.3e-39 136.8 16.0 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF572) T6PP_N PF18572.1 EAN30943.1 - 2.2 8.2 10.0 0.76 9.6 1.8 2.4 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Cpn60_TCP1 PF00118.24 EAN30945.1 - 1e-143 479.6 8.5 1.2e-143 479.3 8.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SF3b1 PF08920.10 EAN30947.1 - 2.3e-27 95.9 4.4 2.3e-27 95.9 4.4 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 EAN30947.1 - 6e-13 49.0 0.7 0.061 13.7 0.0 7.9 5 2 2 8 8 8 3 HEAT repeats HEAT PF02985.22 EAN30947.1 - 1e-10 40.9 6.2 0.013 15.7 0.0 8.4 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.6 EAN30947.1 - 1.1e-10 41.8 0.1 0.27 11.8 0.0 7.8 8 1 1 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.20 EAN30947.1 - 2.3e-05 23.2 1.4 0.004 15.8 1.4 3.2 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAN30947.1 - 6.1e-05 23.1 2.4 1.2 9.1 0.0 5.3 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EAN30947.1 - 9.8e-05 22.0 0.4 0.75 9.3 0.0 3.6 3 0 0 3 3 3 1 CLASP N terminal Arm PF00514.23 EAN30947.1 - 0.0008 19.4 1.1 28 4.9 0.1 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat ParcG PF10274.9 EAN30947.1 - 0.00083 19.5 1.7 2 8.5 0.0 4.7 2 1 2 4 4 4 1 Parkin co-regulated protein UME PF08064.13 EAN30947.1 - 0.00098 19.0 4.1 4.7 7.2 0.0 5.9 5 2 2 7 7 7 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 EAN30947.1 - 0.018 15.6 0.4 1.6 9.4 0.0 3.7 4 0 0 4 4 2 0 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EAN30947.1 - 0.026 13.6 0.0 7.8 5.5 0.0 4.0 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal TetR_C_23 PF17931.1 EAN30947.1 - 0.026 14.6 0.1 0.091 12.9 0.1 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NUC173 PF08161.12 EAN30947.1 - 0.045 13.4 0.0 3.8 7.1 0.0 3.6 3 0 0 3 3 3 0 NUC173 domain FAINT PF04385.15 EAN30948.1 - 5.5e-54 180.2 60.2 3.3e-08 33.5 0.6 11.3 11 0 0 11 11 11 10 Domain of unknown function, DUF529 Uteroglobin PF01099.17 EAN30949.1 - 0.006 16.9 0.6 0.006 16.9 0.6 1.9 2 0 0 2 2 2 1 Uteroglobin family NleF_casp_inhib PF16809.5 EAN30949.1 - 0.02 14.8 4.4 0.031 14.2 4.4 1.4 1 0 0 1 1 1 0 NleF caspase inhibitor Tropomyosin_1 PF12718.7 EAN30949.1 - 0.05 13.7 2.2 0.096 12.8 2.2 1.4 1 0 0 1 1 1 0 Tropomyosin like PCRF PF03462.18 EAN30949.1 - 0.072 12.9 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 PCRF domain KELK PF15796.5 EAN30949.1 - 0.12 12.9 0.9 0.9 10.0 0.1 2.3 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Prp19 PF08606.11 EAN30950.1 - 1.1e-29 102.2 1.6 2e-29 101.4 1.0 1.7 1 1 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 EAN30950.1 - 5e-22 77.8 9.9 2.7e-06 28.0 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN30950.1 - 2.1e-09 37.5 0.0 0.1 12.9 0.0 5.1 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 EAN30950.1 - 1.5e-05 25.1 0.0 4.3e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 U-box domain Hira PF07569.11 EAN30950.1 - 0.061 13.0 0.1 2.3 7.9 0.0 2.5 1 1 1 2 2 2 0 TUP1-like enhancer of split DEAD PF00270.29 EAN30951.1 - 3.3e-29 101.9 0.1 6.6e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN30951.1 - 5.2e-22 78.3 0.8 3e-21 75.8 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN30951.1 - 6.8e-08 32.7 0.1 1.4e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EAN30951.1 - 0.0017 17.3 0.2 0.058 12.2 0.1 2.2 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 EAN30951.1 - 0.026 14.8 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP-grasp_6 PF18419.1 EAN30951.1 - 0.034 13.8 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 ATP-grasp-like domain FAINT PF04385.15 EAN30952.1 - 0.12 12.4 0.1 0.21 11.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN30953.1 - 5e-14 52.1 19.2 2.1e-07 30.9 5.1 2.8 3 0 0 3 3 3 2 Domain of unknown function, DUF529 DUF5617 PF18493.1 EAN30953.1 - 0.014 15.5 0.6 0.025 14.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) FAINT PF04385.15 EAN30954.1 - 1.9e-08 34.2 11.0 1.5e-05 25.0 5.2 2.6 2 1 0 2 2 2 2 Domain of unknown function, DUF529 IMPDH PF00478.25 EAN30955.1 - 3.8e-122 407.6 0.7 4.5e-122 407.4 0.7 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EAN30955.1 - 1.5e-11 44.3 0.0 4.8e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase CBS PF00571.28 EAN30955.1 - 1.6e-10 41.2 0.7 0.00059 20.2 0.0 3.8 4 0 0 4 4 3 2 CBS domain FMN_dh PF01070.18 EAN30955.1 - 3.6e-08 32.8 3.5 1.1e-07 31.2 3.0 2.0 2 1 0 2 2 2 1 FMN-dependent dehydrogenase ThiG PF05690.14 EAN30955.1 - 0.00027 20.3 0.2 0.00054 19.4 0.2 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EAN30955.1 - 0.00051 19.6 0.7 0.088 12.3 0.1 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein Aldolase PF01081.19 EAN30955.1 - 0.0012 18.3 0.6 0.01 15.3 0.2 2.3 2 0 0 2 2 2 1 KDPG and KHG aldolase Glu_synthase PF01645.17 EAN30955.1 - 0.0015 17.7 0.3 0.0033 16.6 0.3 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EAN30955.1 - 0.0016 17.7 1.1 0.0026 17.0 0.2 1.8 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase NanE PF04131.14 EAN30955.1 - 0.013 14.7 0.7 0.2 10.8 0.5 2.4 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase B12-binding PF02310.19 EAN30955.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain Dus PF01207.17 EAN30955.1 - 0.13 11.3 0.1 12 4.9 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) SYF2 PF08231.12 EAN30956.1 - 2.2e-32 112.7 10.6 2.4e-32 112.5 10.6 1.0 1 0 0 1 1 1 1 SYF2 splicing factor DUF4479 PF14794.6 EAN30956.1 - 0.048 13.5 0.6 0.17 11.8 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4479) Rhamno_transf PF11316.8 EAN30956.1 - 0.13 11.6 1.2 0.32 10.3 1.2 1.7 1 1 0 1 1 1 0 Putative rhamnosyl transferase Pro_isomerase PF00160.21 EAN30957.1 - 1.9e-18 67.2 0.0 3.5e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L24e PF01246.20 EAN30958.1 - 1e-31 109.0 3.6 1e-31 109.0 3.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 EAN30958.1 - 0.14 12.1 4.6 0.076 13.0 2.2 1.9 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif MIOX PF05153.15 EAN30959.1 - 0.0023 17.5 0.6 0.0039 16.8 0.6 1.3 1 0 0 1 1 1 1 Myo-inositol oxygenase TetR_C_10 PF16295.5 EAN30959.1 - 0.31 11.3 3.0 0.69 10.2 1.5 2.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Skp1 PF01466.19 EAN30960.1 - 4.8e-21 74.6 0.1 4.8e-21 74.6 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EAN30960.1 - 2.6e-18 65.9 1.6 5.1e-18 65.0 1.6 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Myb_DNA-binding PF00249.31 EAN30960.1 - 0.1 12.8 0.4 11 6.3 0.0 3.1 3 0 0 3 3 3 0 Myb-like DNA-binding domain SCAN PF02023.17 EAN30960.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.5 1 1 0 1 1 1 0 SCAN domain RRM_1 PF00076.22 EAN30961.1 - 8.6e-20 70.3 0.0 1.2e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAN30961.1 - 2.9e-06 26.9 0.0 3.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAN30961.1 - 0.00056 19.7 0.0 0.00075 19.3 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Pyr_redox_2 PF07992.14 EAN30962.1 - 2.8e-60 204.1 0.5 3.7e-60 203.6 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EAN30962.1 - 9.1e-32 109.6 0.0 2.1e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EAN30962.1 - 2.3e-21 76.2 3.3 1.5e-17 63.9 0.3 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAN30962.1 - 1.5e-10 41.1 0.9 2.4e-05 24.4 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EAN30962.1 - 5e-10 39.1 5.2 5e-05 22.7 0.6 3.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAN30962.1 - 4e-09 35.7 5.2 0.0013 17.5 0.1 3.9 3 1 1 4 4 4 3 HI0933-like protein FAD_oxidored PF12831.7 EAN30962.1 - 3.4e-08 33.3 0.4 8e-08 32.0 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EAN30962.1 - 4.6e-08 32.6 1.0 7.8e-05 21.9 0.2 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.24 EAN30962.1 - 5e-08 32.9 2.7 0.046 13.3 0.0 4.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAN30962.1 - 5.7e-08 32.3 6.5 8.8e-06 25.0 0.3 3.6 3 1 1 4 4 4 2 FAD binding domain Thi4 PF01946.17 EAN30962.1 - 1.4e-05 24.5 0.0 0.00068 19.0 0.0 2.5 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EAN30962.1 - 7.3e-05 22.2 0.1 0.0049 16.2 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EAN30962.1 - 0.00022 21.2 1.3 0.045 13.6 0.1 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EAN30962.1 - 0.0016 17.5 0.6 0.1 11.6 0.2 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 EAN30962.1 - 0.0044 16.2 0.1 1.7 7.7 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EAN30962.1 - 0.011 15.0 6.0 0.22 10.7 0.3 3.1 2 1 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 EAN30962.1 - 0.013 15.4 0.2 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.6 EAN30962.1 - 0.021 15.3 0.0 6.6 7.3 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 EAN30962.1 - 0.036 13.4 0.0 0.65 9.3 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 EAN30962.1 - 0.14 11.4 1.0 1.5 8.0 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase PhaC_N PF07167.13 EAN30962.1 - 0.14 11.8 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Ribosomal_L27 PF01016.19 EAN30963.1 - 3.7e-25 87.8 0.3 4.9e-25 87.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein FAD_binding_2 PF00890.24 EAN30965.1 - 2.1e-110 369.7 0.4 1.3e-109 367.1 0.2 2.2 2 1 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 EAN30965.1 - 7.2e-38 129.5 0.2 1.2e-37 128.7 0.2 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EAN30965.1 - 0.0019 17.4 0.5 0.18 10.9 0.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EAN30965.1 - 0.0055 16.0 0.2 0.019 14.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAN30965.1 - 0.0067 15.7 0.1 0.0067 15.7 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EAN30965.1 - 0.037 13.3 2.4 3.1 7.0 0.0 3.4 2 1 0 3 3 3 0 Thi4 family Lycopene_cycl PF05834.12 EAN30965.1 - 0.081 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein RTC PF01137.21 EAN30966.1 - 2.6e-16 59.5 0.0 9.3e-16 57.7 0.0 1.8 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EAN30966.1 - 6.4e-09 36.3 0.0 4.8e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain FAINT PF04385.15 EAN30967.1 - 4.9e-06 26.5 13.8 0.00072 19.6 0.2 3.6 3 0 0 3 3 3 2 Domain of unknown function, DUF529 Tubulin PF00091.25 EAN30968.1 - 6e-69 232.2 0.2 1.3e-68 231.1 0.2 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAN30968.1 - 5.9e-27 94.3 1.3 6.4e-26 91.0 0.6 2.4 2 1 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EAN30968.1 - 4.8e-07 30.1 0.0 1.6e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain CEBP1_N PF16368.5 EAN30968.1 - 1.7 8.1 4.7 0.61 9.6 0.7 2.0 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus DUF900 PF05990.12 EAN30970.1 - 1.1e-23 84.0 0.0 2.1e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) MCM PF00493.23 EAN30971.1 - 8.2e-92 306.3 0.6 1.7e-91 305.3 0.1 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_lid PF17855.1 EAN30971.1 - 1.7e-18 66.8 0.5 5e-18 65.3 0.5 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 EAN30971.1 - 3.7e-12 46.2 0.5 8.4e-10 38.6 0.3 2.4 2 0 0 2 2 2 1 MCM OB domain Mg_chelatase PF01078.21 EAN30971.1 - 2e-09 37.1 0.1 4.4e-06 26.2 0.0 2.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAN30971.1 - 9.2e-09 35.4 0.0 3.1e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EAN30971.1 - 2.6e-06 27.3 0.0 1.4e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAN30971.1 - 0.00032 20.5 0.1 0.0018 18.0 0.0 2.2 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 EAN30971.1 - 0.0047 17.3 0.3 0.36 11.2 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain BDM PF10684.9 EAN30971.1 - 0.013 15.8 0.0 0.048 14.0 0.0 1.9 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein RP-C_C PF11800.8 EAN30971.1 - 0.59 10.2 3.3 1.2 9.2 3.3 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region AAA_2 PF07724.14 EAN30971.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.3 3 1 1 4 4 4 0 AAA domain (Cdc48 subfamily) FH2 PF02181.23 EAN30972.1 - 3.8e-30 105.3 12.6 2.9e-29 102.3 12.7 2.2 1 1 0 1 1 1 1 Formin Homology 2 Domain PTEN_C2 PF10409.9 EAN30972.1 - 5.3e-07 29.5 0.2 2e-06 27.6 0.2 2.1 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein KIND PF16474.5 EAN30972.1 - 7.3 6.4 7.3 1.2 9.0 0.2 2.7 3 0 0 3 3 3 0 Kinase non-catalytic C-lobe domain polyprenyl_synt PF00348.17 EAN30973.1 - 5.1e-47 160.1 0.0 7.8e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase Sec34 PF04136.15 EAN30974.1 - 0.0002 21.3 18.2 0.00035 20.5 16.8 2.2 1 1 0 1 1 1 1 Sec34-like family zf-HIT PF04438.16 EAN30975.1 - 2.1e-07 30.7 12.5 4.3e-07 29.7 12.5 1.6 1 0 0 1 1 1 1 HIT zinc finger MMU163 PF17119.5 EAN30975.1 - 0.065 12.4 0.4 0.13 11.4 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Sulfatase_C PF14707.6 EAN30975.1 - 0.17 12.6 1.4 3.9 8.2 0.0 2.8 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase Guanylate_cyc PF00211.20 EAN30976.1 - 1.6e-15 57.2 1.8 2.1e-06 27.5 0.1 3.7 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain FAINT PF04385.15 EAN30977.1 - 6.5e-53 176.7 128.1 2.8e-08 33.7 6.3 14.1 12 2 2 14 14 14 12 Domain of unknown function, DUF529 Gal-bind_lectin PF00337.22 EAN30977.1 - 0.031 13.8 0.0 10 5.7 0.0 3.9 3 2 0 3 3 3 0 Galactoside-binding lectin FAINT PF04385.15 EAN30978.1 - 2.7e-71 235.6 160.0 2.1e-07 30.9 4.9 17.4 17 1 0 17 17 17 15 Domain of unknown function, DUF529 DUF3139 PF11337.8 EAN30978.1 - 0.3 11.8 20.9 0.076 13.7 0.7 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3139) SDA1 PF05285.12 EAN30979.1 - 0.01 15.3 17.9 0.02 14.4 17.9 1.4 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 EAN30979.1 - 0.058 13.1 16.7 0.17 11.6 16.7 1.8 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EAN30979.1 - 0.069 11.4 22.9 0.0058 14.9 17.2 1.9 2 0 0 2 2 2 0 Nop14-like family tRNA-Thr_ED PF08915.11 EAN30979.1 - 0.26 11.3 6.3 0.13 12.4 1.2 3.1 3 0 0 3 3 3 0 Archaea-specific editing domain of threonyl-tRNA synthetase Drc1-Sld2 PF11719.8 EAN30979.1 - 0.57 9.7 11.6 1.3 8.5 11.6 1.6 1 0 0 1 1 1 0 DNA replication and checkpoint protein Sporozoite_P67 PF05642.11 EAN30979.1 - 5.6 4.9 10.6 14 3.6 10.6 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UPF0184 PF03670.13 EAN30983.1 - 0.23 11.9 0.3 0.23 11.9 0.3 4.2 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) DegS PF05384.11 EAN30983.1 - 0.81 9.2 8.0 0.046 13.2 0.9 2.4 2 0 0 2 2 2 0 Sensor protein DegS GRASP55_65 PF04495.14 EAN30984.1 - 9e-51 171.8 1.7 3.5e-44 150.5 0.1 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 EAN30984.1 - 0.00034 20.9 0.0 0.5 10.7 0.0 3.1 2 1 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EAN30984.1 - 0.2 11.5 0.2 1.6 8.6 0.0 2.6 3 0 0 3 3 3 0 PDZ domain ATAD4 PF15321.6 EAN30984.1 - 3.6 9.0 5.1 1 10.8 0.6 2.2 1 1 1 2 2 2 0 ATPase family AAA domain containing 4 PI3K_1B_p101 PF10486.9 EAN30984.1 - 3.9 5.1 9.3 5.2 4.7 9.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ECH_2 PF16113.5 EAN30985.1 - 4.9e-18 65.7 0.0 6e-15 55.6 0.0 2.7 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EAN30985.1 - 0.056 12.7 0.0 1.5 8.1 0.0 2.6 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase DEAD PF00270.29 EAN30986.1 - 5.7e-15 55.5 0.0 2.4e-14 53.5 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 EAN30986.1 - 0.0019 18.2 0.0 0.0075 16.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAN30986.1 - 0.005 17.2 0.1 0.022 15.1 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ependymin PF00811.18 EAN30986.1 - 0.042 14.1 0.0 0.17 12.1 0.0 2.1 1 1 0 1 1 1 0 Ependymin AAA_22 PF13401.6 EAN30986.1 - 0.13 12.6 0.0 0.5 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain TBP PF00352.21 EAN30987.1 - 8.9e-16 57.6 1.7 3.3e-07 30.2 0.1 3.0 2 1 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EAN30987.1 - 0.039 14.1 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) GYR PF02756.14 EAN30987.1 - 3.3 7.5 4.7 5.7 6.8 4.7 1.4 1 0 0 1 1 1 0 GYR motif ATP_bind_1 PF03029.17 EAN30989.1 - 3e-52 177.8 0.2 1.7e-37 129.5 0.1 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EAN30989.1 - 0.00023 21.0 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 EAN30989.1 - 0.0014 19.1 1.6 0.0054 17.3 0.1 2.5 2 2 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EAN30989.1 - 0.0097 15.9 0.0 0.035 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EAN30989.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_16 PF13191.6 EAN30989.1 - 0.078 13.4 0.0 2.4 8.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EAN30989.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EAN30989.1 - 0.12 12.8 0.1 0.43 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EAN30989.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EAN30989.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain MTCP1 PF08991.10 EAN30991.1 - 0.0085 16.3 3.5 0.013 15.7 3.5 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Acatn PF13000.7 EAN30993.1 - 3.7e-77 260.1 24.5 3.4e-65 220.6 8.8 3.7 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 ATP_bind_3 PF01171.20 EAN30994.1 - 1.4e-11 44.5 1.0 0.0016 18.3 0.1 3.2 3 0 0 3 3 3 3 PP-loop family ATP_bind_3 PF01171.20 EAN30995.1 - 1.2e-07 31.7 0.5 2.5e-07 30.6 0.5 1.5 1 0 0 1 1 1 1 PP-loop family DUF2007 PF09413.10 EAN30995.1 - 0.029 14.5 0.0 0.065 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein Autophagy_act_C PF03987.15 EAN30996.1 - 1.3e-13 51.3 0.3 6.5e-13 49.1 0.0 2.2 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_N PF03986.13 EAN30996.1 - 4.7e-11 42.8 0.1 6.4e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain RabGAP-TBC PF00566.18 EAN30997.1 - 1.7e-44 152.0 0.7 2.6e-44 151.5 0.7 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Erp_C PF06780.11 EAN30997.1 - 0.023 14.7 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 Erp protein C-terminus FAINT PF04385.15 EAN30998.1 - 0.0024 17.9 18.6 0.0027 17.7 0.5 5.3 4 1 1 5 5 5 3 Domain of unknown function, DUF529 S1-P1_nuclease PF02265.16 EAN30999.1 - 4.2e-11 43.2 0.0 1.1e-08 35.3 0.0 2.1 2 0 0 2 2 2 2 S1/P1 Nuclease DUF986 PF06173.12 EAN30999.1 - 0.011 15.8 2.2 0.023 14.8 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF986) S-methyl_trans PF02574.16 EAN31000.1 - 0.037 13.8 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Homocysteine S-methyltransferase CKS PF01111.19 EAN31001.1 - 2.5e-21 75.7 0.1 4.8e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PRP38 PF03371.15 EAN31002.1 - 7.8e-58 195.2 0.1 8.9e-58 195.0 0.1 1.0 1 0 0 1 1 1 1 PRP38 family s48_45 PF07422.13 EAN31003.1 - 4.1e-18 65.9 6.3 1.3e-14 54.6 0.1 3.7 3 0 0 3 3 3 2 Sexual stage antigen s48/45 domain DUF913 PF06025.12 EAN31003.1 - 1.1 8.1 3.4 2.1 7.2 3.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ribosomal_L2_C PF03947.18 EAN31004.1 - 3.1e-42 143.8 0.1 4.7e-42 143.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EAN31004.1 - 7.3e-27 93.1 0.1 1.8e-26 91.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain tRNA_anti-codon PF01336.25 EAN31006.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Sec34 PF04136.15 EAN31008.1 - 0.0061 16.4 0.3 0.0079 16.1 0.3 1.1 1 0 0 1 1 1 1 Sec34-like family APG17 PF04108.12 EAN31008.1 - 0.028 13.5 0.4 0.034 13.3 0.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 ORC4_C PF14629.6 EAN31008.1 - 0.029 13.8 0.3 0.031 13.6 0.3 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Transposase_mut PF00872.18 EAN31008.1 - 0.038 12.9 0.2 0.043 12.7 0.2 1.0 1 0 0 1 1 1 0 Transposase, Mutator family Fib_alpha PF08702.10 EAN31008.1 - 0.046 13.9 0.1 0.057 13.6 0.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4509 PF14970.6 EAN31008.1 - 0.055 13.4 0.1 0.06 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Suf PF05843.14 EAN31008.1 - 0.062 13.3 0.4 0.072 13.1 0.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PLU-1 PF08429.11 EAN31008.1 - 0.065 12.4 0.1 0.071 12.3 0.1 1.0 1 0 0 1 1 1 0 PLU-1-like protein Retrotrans_gag PF03732.17 EAN31008.1 - 0.087 13.1 0.2 0.36 11.1 0.1 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein TMF_TATA_bd PF12325.8 EAN31008.1 - 0.1 12.8 0.1 0.17 12.1 0.1 1.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding RPW8 PF05659.11 EAN31008.1 - 0.12 12.1 0.7 7.8 6.2 0.1 2.0 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 WD40 PF00400.32 EAN31010.1 - 8.1e-06 26.5 6.1 11 7.0 0.1 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.11 EAN31010.1 - 0.014 15.2 0.0 12 5.7 0.0 3.5 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A MIF4G PF02854.19 EAN31011.1 - 1.2e-28 100.2 4.5 1.6e-28 99.8 4.5 1.2 1 0 0 1 1 1 1 MIF4G domain HigB_toxin PF09907.9 EAN31011.1 - 0.044 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system ATP-synt_Eps PF04627.13 EAN31013.1 - 6.6e-16 58.0 0.1 7.2e-16 57.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain GTP_EFTU PF00009.27 EAN31014.1 - 2.9e-45 154.2 0.4 8.6e-45 152.7 0.1 1.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EAN31014.1 - 2e-13 50.2 0.2 5e-13 48.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 EAN31014.1 - 1.4e-05 25.1 0.1 4.1e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EAN31014.1 - 7.2e-05 22.8 0.0 0.00019 21.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II Septin PF00735.18 EAN31014.1 - 0.0032 16.8 0.1 0.0083 15.4 0.1 1.6 1 0 0 1 1 1 1 Septin FeoB_N PF02421.18 EAN31014.1 - 0.0053 16.3 0.2 0.028 13.9 0.2 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 EAN31014.1 - 0.015 14.8 0.1 0.041 13.3 0.1 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 EAN31014.1 - 0.017 15.5 0.6 0.059 13.8 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Ras PF00071.22 EAN31014.1 - 0.029 14.0 0.2 0.076 12.6 0.0 1.8 2 0 0 2 2 2 0 Ras family DUF5025 PF16428.5 EAN31014.1 - 0.043 14.0 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5025) Peptidase_C1 PF00112.23 EAN31015.1 - 3.9e-58 197.1 1.5 5.6e-58 196.6 1.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAN31015.1 - 2.9e-07 30.8 5.9 6.2e-07 29.8 5.9 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAN31015.1 - 2.7e-05 23.2 0.1 0.0002 20.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EAN31016.1 - 7.1e-36 124.3 0.0 7.1e-36 124.3 0.0 1.8 3 0 0 3 3 3 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAN31016.1 - 0.0013 19.2 6.9 0.0035 17.7 6.9 1.9 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) NUC130_3NT PF08158.12 EAN31016.1 - 0.04 14.3 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 NUC130/3NT domain Borrelia_P83 PF05262.11 EAN31016.1 - 0.34 9.4 11.1 0.12 10.8 6.9 2.0 2 0 0 2 2 2 0 Borrelia P83/100 protein Eisosome1 PF12757.7 EAN31016.1 - 0.69 10.2 12.4 9.8 6.5 12.3 2.4 2 0 0 2 2 2 0 Eisosome protein 1 Peptidase_C1 PF00112.23 EAN31017.1 - 2.9e-52 177.9 0.3 4.4e-52 177.3 0.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAN31017.1 - 2.8e-08 34.1 0.5 6.2e-08 33.0 0.5 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAN31017.1 - 0.00064 18.6 0.2 0.00064 18.6 0.2 2.2 3 0 0 3 3 3 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EAN31018.1 - 4.5e-57 193.6 0.1 8.4e-57 192.8 0.0 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAN31018.1 - 1.8e-10 41.1 2.4 3.3e-10 40.3 2.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAN31018.1 - 6.4e-06 25.2 0.4 0.00011 21.1 0.1 2.1 2 0 0 2 2 2 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EAN31019.1 - 3e-51 174.6 0.1 4e-51 174.2 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAN31019.1 - 6.9e-08 32.8 1.7 1.6e-07 31.7 1.7 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAN31019.1 - 0.0027 16.5 0.1 0.014 14.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EAN31020.1 - 5e-60 203.3 3.9 7e-60 202.8 3.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAN31020.1 - 8.1e-09 35.8 3.4 1.5e-07 31.7 1.7 2.5 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAN31020.1 - 1.4e-07 30.7 3.3 2.8e-05 23.1 0.5 2.6 2 1 1 3 3 3 2 Peptidase C1-like family BolA PF01722.18 EAN31021.1 - 0.0015 18.7 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein Sporozoite_P67 PF05642.11 EAN31022.1 - 8.5e-302 1002.7 43.4 2e-221 737.0 0.5 3.1 1 1 2 3 3 3 3 Sporozoite P67 surface antigen MMR_HSR1 PF01926.23 EAN31023.1 - 1.3e-21 76.8 0.3 3.4e-20 72.2 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase KH_dom-like PF14714.6 EAN31023.1 - 2e-20 72.9 0.4 8.8e-20 70.8 0.0 2.4 3 0 0 3 3 3 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal AIG1 PF04548.16 EAN31023.1 - 2.8e-06 26.8 0.0 5.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 EAN31023.1 - 4e-06 26.4 0.0 1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EAN31023.1 - 5.4e-05 22.8 0.0 0.0039 16.8 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAN31023.1 - 0.00035 20.5 0.1 0.0064 16.4 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 EAN31023.1 - 0.0089 15.3 0.3 0.075 12.3 0.1 2.6 2 1 0 2 2 2 1 Septin AAA_22 PF13401.6 EAN31023.1 - 0.029 14.6 0.0 0.26 11.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 EAN31023.1 - 0.12 12.6 0.1 0.58 10.4 0.1 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 EAN31024.1 - 6.7e-12 46.0 0.0 1.2e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sarcoglycan_1 PF04790.13 EAN31024.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein DUF3540 PF12059.8 EAN31024.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) MRNIP PF15749.5 EAN31025.1 - 0.4 11.4 3.5 0.35 11.6 1.3 1.9 2 0 0 2 2 2 0 MRN-interacting protein EamA PF00892.20 EAN31026.1 - 1.2e-08 35.2 4.7 1.9e-08 34.6 4.7 1.3 1 0 0 1 1 1 1 EamA-like transporter family PUNUT PF16913.5 EAN31026.1 - 0.015 14.5 1.2 0.016 14.5 1.2 1.1 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport PROCN PF08083.11 EAN31027.1 - 5.4e-227 753.2 7.1 8.1e-227 752.7 7.1 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EAN31027.1 - 2.9e-123 409.9 0.6 4.9e-123 409.2 0.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EAN31027.1 - 4.6e-88 293.2 4.2 5.4e-88 292.9 2.7 2.0 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EAN31027.1 - 2.3e-83 277.6 3.1 2.3e-83 277.6 3.1 2.1 2 0 0 2 2 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EAN31027.1 - 5.7e-71 236.8 0.2 1.1e-70 235.9 0.2 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EAN31027.1 - 4e-43 145.7 0.2 9.7e-43 144.4 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EAN31027.1 - 1.4e-27 96.1 1.6 3.6e-26 91.5 1.6 2.5 1 1 0 1 1 1 1 PROCT (NUC072) domain Transformer PF06495.11 EAN31027.1 - 0.0059 16.7 23.6 0.024 14.8 23.6 2.0 1 0 0 1 1 1 1 Fruit fly transformer protein Collagen PF01391.18 EAN31027.1 - 0.062 13.1 0.3 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF4778 PF16008.5 EAN31027.1 - 1.2 9.2 14.0 2.5 8.1 11.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) Astro_capsid_N PF03115.14 EAN31027.1 - 1.9 7.1 9.2 3.4 6.2 9.2 1.4 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Proteasome PF00227.26 EAN31028.1 - 2e-31 109.0 0.2 7.2e-31 107.2 0.2 1.9 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAN31028.1 - 2.6e-14 52.6 0.1 7.3e-14 51.1 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-CCCH PF00642.24 EAN31029.1 - 1.1e-10 41.1 13.8 1.6e-05 24.7 4.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAN31029.1 - 2.4e-06 27.4 13.9 0.0021 18.0 5.3 2.7 2 1 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EAN31029.1 - 5e-05 24.0 3.1 0.21 12.3 0.4 2.4 2 0 0 2 2 2 2 Torus domain Stealth_CR3 PF17102.5 EAN31029.1 - 0.00046 20.0 0.8 0.00046 20.0 0.8 2.0 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 zf-CCCH_3 PF15663.5 EAN31029.1 - 0.02 15.1 3.6 3.1 8.1 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger containing family RRM_1 PF00076.22 EAN31029.1 - 0.021 14.6 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EAN31029.1 - 0.059 13.2 0.4 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) zf-CCCH_4 PF18044.1 EAN31029.1 - 0.17 11.7 15.2 0.86 9.5 6.5 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger Strep_SA_rep PF06696.11 EAN31030.1 - 0.13 12.3 0.4 0.27 11.3 0.4 1.5 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Sec20 PF03908.13 EAN31030.1 - 0.19 11.7 2.2 0.3 11.0 0.7 2.1 2 0 0 2 2 2 0 Sec20 Pkinase PF00069.25 EAN31031.1 - 4.3e-32 111.5 0.0 3.9e-15 55.9 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EAN31031.1 - 4.7e-20 72.0 0.0 3.7e-18 65.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAN31031.1 - 0.054 13.4 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FAM25 PF15825.5 EAN31031.1 - 0.81 10.1 5.3 2.1 8.8 5.3 1.7 1 0 0 1 1 1 0 FAM25 family AAA_lid_10 PF17872.1 EAN31031.1 - 1.8 8.7 6.7 1.8 8.7 0.8 2.9 2 0 0 2 2 2 0 AAA lid domain FAINT PF04385.15 EAN31032.1 - 5.6e-31 106.4 34.4 3.5e-09 36.6 1.3 4.4 4 0 0 4 4 4 4 Domain of unknown function, DUF529 UDPGT PF00201.18 EAN31032.1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.4 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase SLD5_C PF16922.5 EAN31033.1 - 0.17 12.1 0.5 8.2 6.7 0.0 2.9 3 0 0 3 3 3 0 DNA replication complex GINS protein SLD5 C-terminus SEP PF08059.13 EAN31035.1 - 4.3e-14 52.8 0.0 7.5e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EAN31035.1 - 0.00017 21.7 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain Ubiquitin_4 PF18036.1 EAN31035.1 - 0.0048 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Ribosomal_S6 PF01250.17 EAN31036.1 - 1.7e-08 34.6 0.0 2.3e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 RF-1 PF00472.20 EAN31037.1 - 1.4e-15 57.2 1.3 2.9e-15 56.2 1.3 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.18 EAN31037.1 - 9.1e-15 55.0 1.9 5.6e-13 49.2 1.9 2.2 1 1 0 1 1 1 1 PCRF domain SF-assemblin PF06705.11 EAN31037.1 - 0.025 13.9 0.2 0.04 13.3 0.2 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin IFN-gamma PF00714.17 EAN31037.1 - 0.036 13.9 0.4 0.084 12.7 0.4 1.7 1 0 0 1 1 1 0 Interferon gamma COG2 PF06148.11 EAN31037.1 - 0.092 12.8 1.0 0.26 11.4 0.5 1.9 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Arv1 PF04161.13 EAN31039.1 - 1e-22 81.4 0.4 1e-22 81.4 0.4 2.6 2 1 0 2 2 2 2 Arv1-like family Vpu PF00558.19 EAN31039.1 - 0.035 13.9 3.5 0.21 11.4 2.5 2.8 1 1 1 2 2 2 0 Vpu protein zf-CHY PF05495.12 EAN31040.1 - 0.04 14.4 0.9 0.085 13.4 0.9 1.5 1 0 0 1 1 1 0 CHY zinc finger Rubredoxin_2 PF18073.1 EAN31040.1 - 7 6.5 9.4 14 5.5 0.4 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain Asp PF00026.23 EAN31041.1 - 2.3e-38 132.4 0.1 1.1e-20 74.3 0.0 3.0 2 1 1 3 3 3 3 Eukaryotic aspartyl protease Asp PF00026.23 EAN31042.1 - 0.00039 19.9 0.1 0.00059 19.4 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Peptidase_S55 PF05580.12 EAN31042.1 - 0.063 13.2 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 SpoIVB peptidase S55 Elong-fact-P_C PF09285.11 EAN31043.1 - 6e-09 35.5 0.8 1.7e-08 34.0 0.2 2.2 2 1 0 2 2 2 1 Elongation factor P, C-terminal EFP_N PF08207.12 EAN31043.1 - 1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Minor_capsid_1 PF10665.9 EAN31043.1 - 0.032 14.4 0.5 0.075 13.2 0.5 1.6 1 0 0 1 1 1 0 Minor capsid protein Methyltransf_8 PF05148.15 EAN31044.1 - 1.7e-68 230.7 0.0 2.1e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EAN31044.1 - 0.031 14.9 0.0 0.19 12.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EAN31044.1 - 0.11 12.1 0.0 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain SMC_hinge PF06470.13 EAN31046.1 - 2.9e-34 117.9 0.3 7.5e-34 116.5 0.3 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 EAN31046.1 - 4.8e-17 62.1 4.2 4.8e-17 62.1 4.2 2.9 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EAN31046.1 - 4.6e-10 39.8 47.0 3.1e-09 37.0 9.4 3.9 1 1 3 4 4 4 2 AAA ATPase domain AAA_21 PF13304.6 EAN31046.1 - 0.00041 20.3 1.2 0.00041 20.3 1.2 2.8 2 2 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAN31046.1 - 0.00057 20.5 32.6 0.00057 20.5 32.6 6.1 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 EAN31046.1 - 0.0021 17.8 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMN PF06003.12 EAN31046.1 - 0.39 9.9 1.5 3.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) SMC_N PF02463.19 EAN31047.1 - 7.1e-16 58.3 0.0 8e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAN31047.1 - 8.3e-05 22.5 0.1 8.7e-05 22.5 0.1 1.0 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system DEAD PF00270.29 EAN31047.1 - 0.049 13.4 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase ApoM PF11032.8 EAN31049.1 - 0.14 11.9 1.2 3.8 7.1 0.0 2.8 2 1 1 3 3 3 0 ApoM domain Pkinase PF00069.25 EAN31050.1 - 2.1e-28 99.4 0.0 2.7e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN31050.1 - 5.2e-17 62.0 0.0 6.4e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAN31050.1 - 8e-09 34.8 0.1 1.1e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAN31050.1 - 8.2e-05 22.6 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EAN31050.1 - 0.015 14.3 0.2 0.015 14.3 0.2 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 EAN31050.1 - 0.36 9.7 1.7 0.9 8.4 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain FAINT PF04385.15 EAN31051.1 - 1.1e-27 95.9 36.5 1.9e-06 27.8 2.3 6.8 6 0 0 6 6 6 6 Domain of unknown function, DUF529 RRM_1 PF00076.22 EAN31051.1 - 9.9e-05 22.1 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Citrate_synt PF00285.21 EAN31052.1 - 4.3e-15 55.7 0.2 1.6e-14 53.7 0.2 1.7 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain Aldo_ket_red PF00248.21 EAN31053.1 - 1.4e-49 168.9 0.0 3e-49 167.8 0.0 1.5 2 0 0 2 2 2 1 Aldo/keto reductase family TxDE PF18711.1 EAN31053.1 - 0.096 12.8 0.0 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 Toxoflavin-degrading enzyme Mrx7 PF10906.8 EAN31054.1 - 0.037 14.3 0.0 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 MIOREX complex component 7 FAINT PF04385.15 EAN31054.1 - 0.085 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Biotin_lipoyl PF00364.22 EAN31055.1 - 3.4e-12 46.0 0.0 5.7e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme S36_mt PF10937.8 EAN31055.1 - 0.016 16.8 0.0 0.027 16.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial Shugoshin_C PF07557.11 EAN31055.1 - 0.11 12.3 0.5 20 5.1 0.1 2.6 2 0 0 2 2 2 0 Shugoshin C terminus GCV_H PF01597.19 EAN31055.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein DnaJ PF00226.31 EAN31056.1 - 0.00033 20.7 0.7 0.00097 19.2 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain Muted PF14942.6 EAN31057.1 - 0.025 14.9 16.3 0.051 13.9 3.0 2.9 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein Gp-FAR-1 PF05823.12 EAN31057.1 - 0.19 12.0 7.4 0.14 12.5 2.9 2.7 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SPARC_Ca_bdg PF10591.9 EAN31057.1 - 0.51 10.7 3.4 0.52 10.6 0.3 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region CS PF04969.16 EAN31059.1 - 8.7e-07 29.9 0.2 9.1e-07 29.8 0.2 1.1 1 0 0 1 1 1 1 CS domain NtCtMGAM_N PF16863.5 EAN31059.1 - 0.041 14.1 0.1 0.044 14.0 0.1 1.0 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Enterotoxin_a PF01375.17 EAN31060.1 - 0.14 11.8 0.0 0.15 11.7 0.0 1.0 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain DUF3959 PF13105.6 EAN31061.1 - 0.13 11.7 2.0 0.16 11.5 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) NOA36 PF06524.12 EAN31061.1 - 5.1 6.3 12.3 5.3 6.3 12.3 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4407 PF14362.6 EAN31061.1 - 8.1 5.7 8.3 9 5.6 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1803 PF08820.10 EAN31062.1 - 0.041 13.9 0.5 0.26 11.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) ER PF01133.17 EAN31062.1 - 0.18 11.9 2.0 0.55 10.3 0.1 2.9 4 0 0 4 4 4 0 Enhancer of rudimentary Ribosomal_L12_N PF16320.5 EAN31063.1 - 8.6e-13 47.8 0.9 1.6e-12 47.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_L12 PF00542.19 EAN31063.1 - 0.00044 20.5 1.1 0.00044 20.5 1.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain CENP-R PF06729.12 EAN31063.1 - 0.26 11.2 3.7 3 7.8 0.2 2.3 1 1 1 2 2 2 0 Kinetochore component, CENP-R Laminin_II PF06009.12 EAN31064.1 - 4.6 7.2 20.6 0.26 11.3 7.1 3.3 3 0 0 3 3 3 0 Laminin Domain II BORCS7 PF16088.5 EAN31064.1 - 8.4 6.7 18.0 0.17 12.2 8.7 2.8 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 7 GAS PF13851.6 EAN31064.1 - 9 5.6 26.9 0.18 11.2 10.7 2.9 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Fmp27 PF10344.9 EAN31065.1 - 0.014 13.5 1.8 0.021 13.0 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF3432 PF11914.8 EAN31065.1 - 0.031 14.5 1.8 0.031 14.5 1.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3432) Cornifin PF02389.15 EAN31065.1 - 0.056 13.6 7.7 0.065 13.4 3.6 2.5 2 0 0 2 2 2 0 Cornifin (SPRR) family PHM7_cyt PF14703.6 EAN31066.1 - 0.00041 20.6 0.2 0.032 14.4 0.2 2.3 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Nudc_N PF14050.6 EAN31067.1 - 2.8e-19 68.8 2.2 5e-19 68.1 2.2 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 EAN31067.1 - 3.2e-12 47.3 1.1 6e-12 46.4 1.1 1.5 1 0 0 1 1 1 1 CS domain Ubiquitin_3 PF14836.6 EAN31067.1 - 0.02 14.9 0.5 0.044 13.8 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain UQ_con PF00179.26 EAN31068.1 - 1.2e-23 83.4 0.0 1.2e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAN31068.1 - 0.032 14.5 0.1 0.034 14.4 0.1 1.3 1 1 0 1 1 1 0 RWD domain RRM_1 PF00076.22 EAN31069.1 - 2.9e-15 55.8 0.1 5.4e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Uso1_p115_head PF04869.14 EAN31071.1 - 0.056 12.6 0.0 0.056 12.6 0.0 2.3 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, head region MFS_1 PF07690.16 EAN31072.1 - 2.6e-18 66.1 22.6 2.6e-18 66.1 22.6 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EAN31072.1 - 3.7e-07 29.8 0.8 3.7e-07 29.8 0.8 2.1 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EAN31072.1 - 0.0018 16.7 33.8 0.039 12.2 1.9 4.3 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 EAN31073.1 - 3.5e-22 78.8 17.5 3.5e-22 78.8 17.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAN31073.1 - 1.3e-12 47.4 3.2 1.3e-12 47.4 3.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EAN31073.1 - 2 6.6 36.8 0.044 12.1 17.4 4.0 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 EAN31074.1 - 1.4e-26 93.3 13.3 1.4e-26 93.3 13.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAN31074.1 - 5.8e-11 41.9 16.1 5.8e-11 41.9 16.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EAN31074.1 - 0.006 14.9 35.7 0.062 11.6 14.1 4.1 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 EAN31075.1 - 1.2e-20 73.8 19.9 1.2e-20 73.8 19.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EAN31076.1 - 9.9e-27 93.8 2.6 9.9e-27 93.8 2.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAN31076.1 - 6.9e-14 51.5 21.5 9.4e-14 51.1 5.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 EAN31076.1 - 0.00037 18.9 30.9 0.004 15.5 10.4 4.0 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family DUF2374 PF09574.10 EAN31076.1 - 0.044 13.6 0.2 0.044 13.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) MFS_1 PF07690.16 EAN31077.1 - 4e-20 72.0 15.3 4e-20 72.0 15.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAN31077.1 - 7.3e-10 38.3 9.2 7.3e-10 38.3 9.2 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EAN31078.1 - 5.4e-21 74.9 23.5 5.4e-21 74.9 23.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAN31078.1 - 8.5e-12 44.7 7.0 8.5e-12 44.7 7.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1057 PF06342.12 EAN31078.1 - 0.027 13.5 0.1 0.042 12.9 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) OATP PF03137.20 EAN31078.1 - 0.15 10.3 36.3 0.016 13.6 14.5 4.2 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family CLTH PF10607.9 EAN31079.1 - 1.9e-24 86.2 2.2 1.9e-24 86.2 2.2 2.7 3 0 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain TniQ PF06527.11 EAN31079.1 - 0.012 16.3 0.0 0.03 15.1 0.0 1.7 1 0 0 1 1 1 0 TniQ 7TMR-HDED PF07697.11 EAN31079.1 - 0.018 15.1 1.8 0.04 14.0 1.9 1.6 1 1 0 1 1 1 0 7TM-HD extracellular SAM_LFY PF01698.16 EAN31079.1 - 0.041 13.8 0.2 3.1 7.8 0.2 2.8 2 1 0 2 2 2 0 Floricaula / Leafy protein SAM domain Baculo_PEP_C PF04513.12 EAN31079.1 - 0.075 13.1 0.6 0.075 13.1 0.6 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BST2 PF16716.5 EAN31079.1 - 2.3 8.9 5.2 28 5.4 1.1 3.4 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 LOH1CR12 PF10158.9 EAN31079.1 - 2.4 8.2 7.1 1.2 9.1 1.8 3.0 3 0 0 3 3 3 0 Tumour suppressor protein XhlA PF10779.9 EAN31079.1 - 3.3 8.0 13.6 2.9 8.2 3.1 3.2 2 1 1 3 3 3 0 Haemolysin XhlA ER_lumen_recept PF00810.18 EAN31080.1 - 2.4e-35 122.5 9.3 2.4e-35 122.5 9.3 2.3 3 0 0 3 3 3 1 ER lumen protein retaining receptor PIG-U PF06728.13 EAN31081.1 - 2.2e-07 30.3 27.5 3.1e-07 29.8 25.6 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U WGG PF10273.9 EAN31081.1 - 4.7e-05 24.0 0.0 9.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 EAN31081.1 - 0.022 14.9 0.3 0.039 14.1 0.3 1.3 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain PGI PF00342.19 EAN31082.1 - 7.5e-160 532.7 0.0 9.2e-160 532.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF676 PF05057.14 EAN31083.1 - 1.9e-07 30.8 0.0 5.9e-06 25.9 0.0 2.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EAN31083.1 - 0.0093 15.7 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 EAN31083.1 - 0.015 15.1 0.0 0.063 13.1 0.0 2.0 2 1 1 3 3 3 0 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EAN31083.1 - 0.025 14.2 0.0 0.081 12.5 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold BT1 PF03092.16 EAN31084.1 - 5.8e-42 143.6 18.8 5.5e-24 84.3 2.6 2.1 1 1 1 2 2 2 2 BT1 family MFS_1 PF07690.16 EAN31084.1 - 3e-10 39.5 25.5 3e-10 39.5 25.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EAN31084.1 - 0.0001 21.3 17.7 0.0001 21.3 17.7 2.1 1 1 1 2 2 2 1 MFS_1 like family BT1 PF03092.16 EAN31085.1 - 1.6e-44 152.1 19.9 4e-24 84.7 2.3 2.1 2 0 0 2 2 2 2 BT1 family MFS_1 PF07690.16 EAN31085.1 - 8.8e-10 38.0 33.5 3.3e-06 26.3 8.9 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 EAN31085.1 - 2.9 6.3 37.4 0.012 14.2 7.5 3.7 1 1 2 3 3 3 0 MFS/sugar transport protein WD40 PF00400.32 EAN31086.1 - 8.3e-05 23.3 0.0 10 7.2 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Pro_isomerase PF00160.21 EAN31087.1 - 6.5e-49 166.2 0.1 7.4e-49 166.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AAA PF00004.29 EAN31088.1 - 1.5e-38 132.2 0.0 2.8e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EAN31088.1 - 1e-12 47.9 0.2 1.7e-10 40.7 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.18 EAN31088.1 - 1.3e-08 34.9 0.5 6.2e-08 32.7 0.5 2.0 1 1 0 1 1 1 1 Bacterial dnaA protein RuvB_N PF05496.12 EAN31088.1 - 1.3e-06 28.3 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAN31088.1 - 2e-06 28.2 0.1 0.0011 19.3 0.0 3.2 1 1 2 3 3 3 1 AAA domain AAA_18 PF13238.6 EAN31088.1 - 4.9e-06 27.1 1.0 4.2e-05 24.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain MIT PF04212.18 EAN31088.1 - 5.1e-06 26.5 0.6 9.5e-06 25.6 0.6 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain IstB_IS21 PF01695.17 EAN31088.1 - 5.3e-06 26.3 0.0 1.6e-05 24.8 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EAN31088.1 - 8.8e-06 25.1 0.0 3.2e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EAN31088.1 - 1.2e-05 25.3 1.3 6.9e-05 22.9 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAN31088.1 - 2.9e-05 24.5 0.0 0.0003 21.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Parvo_NS1 PF01057.17 EAN31088.1 - 8e-05 21.8 0.0 0.00019 20.6 0.0 1.7 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 EAN31088.1 - 8.7e-05 22.9 0.2 0.00052 20.4 0.0 2.4 2 1 0 2 2 2 1 RNA helicase TniB PF05621.11 EAN31088.1 - 0.00033 20.1 0.0 0.43 10.0 0.0 2.6 2 0 0 2 2 2 2 Bacterial TniB protein AAA_5 PF07728.14 EAN31088.1 - 0.00044 20.3 0.0 0.0039 17.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EAN31088.1 - 0.00082 19.1 0.0 0.002 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAN31088.1 - 0.00097 19.3 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EAN31088.1 - 0.0059 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EAN31088.1 - 0.006 17.0 0.0 0.024 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain PPV_E1_C PF00519.17 EAN31088.1 - 0.0065 15.4 0.1 0.011 14.6 0.1 1.3 1 0 0 1 1 1 1 Papillomavirus helicase AAA_7 PF12775.7 EAN31088.1 - 0.0069 15.9 0.1 0.025 14.1 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_2 PF07724.14 EAN31088.1 - 0.0075 16.4 0.0 0.03 14.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) KAP_NTPase PF07693.14 EAN31088.1 - 0.0098 15.2 0.1 0.25 10.5 0.0 2.3 1 1 1 2 2 2 1 KAP family P-loop domain TsaE PF02367.17 EAN31088.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ribosomal_L50 PF10501.9 EAN31088.1 - 0.017 15.3 0.1 0.05 13.7 0.1 1.8 1 0 0 1 1 1 0 Ribosomal subunit 39S T2SSE PF00437.20 EAN31088.1 - 0.022 13.8 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 EAN31088.1 - 0.022 14.2 0.0 0.065 12.6 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EAN31088.1 - 0.025 14.0 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 EAN31088.1 - 0.026 14.3 0.0 0.062 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EAN31088.1 - 0.069 13.1 0.0 0.72 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Guanylate_kin PF00625.21 EAN31088.1 - 0.079 12.6 0.0 0.86 9.3 0.0 2.4 1 1 1 2 2 2 0 Guanylate kinase DUF815 PF05673.13 EAN31088.1 - 0.088 12.0 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EAN31088.1 - 0.1 12.5 0.0 0.36 10.7 0.0 2.0 1 1 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 EAN31088.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EAN31088.1 - 0.14 11.4 0.0 0.42 9.9 0.0 1.7 1 1 0 1 1 1 0 KaiC AAA_25 PF13481.6 EAN31088.1 - 0.17 11.4 0.0 0.7 9.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUSP PF06337.12 EAN31088.1 - 3.1 8.5 7.6 0.36 11.5 0.3 2.7 2 2 0 2 2 2 0 DUSP domain DUF4375 PF14300.6 EAN31089.1 - 3.3 8.0 6.8 0.8 10.0 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) Ssu72 PF04722.13 EAN31093.1 - 0.025 14.2 0.1 0.03 13.9 0.1 1.1 1 0 0 1 1 1 0 Ssu72-like protein Peptidase_C1 PF00112.23 EAN31094.1 - 7.9e-29 101.3 0.7 3.4e-27 96.0 0.7 2.9 1 1 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 EAN31094.1 - 2.2e-07 31.2 0.9 7.1e-07 29.5 0.9 2.0 1 1 0 1 1 1 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.15 EAN31094.1 - 1.7e-05 23.8 0.3 0.00055 18.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Mito_carr PF00153.27 EAN31096.1 - 3.5e-61 203.1 4.5 8.8e-22 76.8 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SPG48 PF14764.6 EAN31097.1 - 0.068 13.6 1.9 0.32 11.5 0.1 2.6 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking LRR19-TM PF15176.6 EAN31097.1 - 0.25 11.4 2.6 1 9.4 2.6 2.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Hydrolase_4 PF12146.8 EAN31098.1 - 1e-10 41.3 0.0 7.8e-06 25.3 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAN31098.1 - 6.4e-08 32.5 2.9 3.6e-05 23.6 0.0 2.4 2 1 0 3 3 3 2 alpha/beta hydrolase fold DUF818 PF05677.12 EAN31098.1 - 1.6e-05 24.1 1.5 6.5e-05 22.0 0.8 2.0 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) DUF1057 PF06342.12 EAN31098.1 - 0.00022 20.4 0.6 0.0011 18.1 0.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S9 PF00326.21 EAN31098.1 - 0.00027 20.5 1.5 0.00049 19.6 0.0 2.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EAN31098.1 - 0.0018 18.1 0.1 0.0091 15.8 0.0 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase PBECR3 PF18812.1 EAN31098.1 - 0.009 16.0 0.2 0.13 12.2 0.0 2.3 2 0 0 2 2 2 1 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 Abhydrolase_6 PF12697.7 EAN31098.1 - 0.017 15.7 0.0 1.2 9.7 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EAN31098.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.13 EAN31098.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Asp2 PF16929.5 EAN31098.1 - 0.038 13.0 0.2 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Accessory Sec system GspB-transporter DLH PF01738.18 EAN31098.1 - 0.17 11.4 0.0 0.67 9.5 0.0 2.0 3 1 0 3 3 3 0 Dienelactone hydrolase family UBA_3 PF09288.10 EAN31099.1 - 0.18 11.7 1.3 9.4 6.1 0.0 2.7 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain YgbB PF02542.16 EAN31102.1 - 1e-54 185.0 0.3 2.2e-54 183.9 0.1 1.6 2 0 0 2 2 2 1 YgbB family NAD_kinase PF01513.21 EAN31103.1 - 2.3e-58 197.7 0.1 2.9e-58 197.4 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EAN31103.1 - 0.001 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF5055 PF16478.5 EAN31103.1 - 0.073 13.3 0.0 0.88 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5055) DASH_Duo1 PF08651.10 EAN31104.1 - 2.7 7.8 16.5 1 9.2 5.9 4.1 3 0 0 3 3 3 0 DASH complex subunit Duo1 FAINT PF04385.15 EAN31105.1 - 7.5e-10 38.7 3.2 2.9e-08 33.7 1.5 2.6 2 1 1 3 3 3 2 Domain of unknown function, DUF529 RHD_DNA_bind PF00554.22 EAN31105.1 - 0.1 12.6 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Rel homology DNA-binding domain SNF PF00209.18 EAN31106.1 - 1.6e-12 46.9 36.4 1.6e-12 46.9 36.4 2.1 2 0 0 2 2 2 1 Sodium:neurotransmitter symporter family SecE PF00584.20 EAN31107.1 - 5.5e-14 51.8 0.1 7.7e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Ribosomal_L37ae PF01780.19 EAN31108.1 - 4.8e-37 125.9 6.7 5.4e-37 125.8 6.7 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 EAN31108.1 - 0.00017 21.5 5.3 0.00025 20.9 5.3 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Sgf11 PF08209.11 EAN31108.1 - 0.0052 16.3 0.4 1.1 8.9 0.0 2.3 2 0 0 2 2 2 2 Sgf11 (transcriptional regulation protein) OrfB_Zn_ribbon PF07282.11 EAN31108.1 - 0.0054 16.6 1.2 0.0086 16.0 1.2 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.10 EAN31108.1 - 0.033 13.9 1.3 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Lar_restr_allev PF14354.6 EAN31108.1 - 0.043 14.2 1.9 0.065 13.6 1.9 1.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar Rep_fac-A_C PF08646.10 EAN31108.1 - 0.047 13.4 0.5 0.063 13.0 0.5 1.3 1 1 0 1 1 1 0 Replication factor-A C terminal domain Elf1 PF05129.13 EAN31108.1 - 0.06 13.4 2.6 0.11 12.6 2.6 1.6 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.6 EAN31108.1 - 0.22 11.5 6.8 2.8 7.9 0.9 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PITH PF06201.13 EAN31109.1 - 5.1e-26 91.7 0.3 6.9e-26 91.3 0.3 1.1 1 0 0 1 1 1 1 PITH domain DEAD PF00270.29 EAN31110.1 - 1e-36 126.3 0.0 1.6e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN31110.1 - 2.6e-26 92.2 0.3 1.6e-25 89.6 0.2 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN31110.1 - 0.00092 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EAN31110.1 - 0.0043 16.4 0.0 0.0086 15.4 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit PSP1 PF04468.12 EAN31110.1 - 0.11 12.8 2.1 0.22 11.8 0.9 2.1 2 0 0 2 2 2 0 PSP1 C-terminal conserved region MFS_1 PF07690.16 EAN31111.1 - 2.8e-15 56.1 25.0 4e-15 55.6 25.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 EAN31112.1 - 9.4e-19 67.6 0.2 1.9e-15 56.9 1.1 3.5 2 1 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 EAN31112.1 - 4.9e-15 56.4 0.0 2.3e-06 28.1 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EAN31112.1 - 0.0052 16.5 0.1 0.016 15.0 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAN31112.1 - 0.16 11.7 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus TFIIB PF00382.19 EAN31113.1 - 2.4e-25 88.3 0.0 2.1e-11 43.7 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EAN31113.1 - 1.5e-12 47.7 2.3 4e-12 46.4 1.9 1.9 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EAN31113.1 - 1.2e-07 31.1 1.0 2.5e-07 30.1 1.0 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 EAN31113.1 - 0.035 13.8 3.3 0.15 11.8 3.3 2.1 1 1 0 1 1 1 0 A2L zinc ribbon domain FliJ PF02050.16 EAN31113.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein zinc_ribbon_2 PF13240.6 EAN31113.1 - 0.37 10.6 2.3 18 5.2 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Tash_PEST PF07708.11 EAN31113.1 - 0.66 10.2 2.5 1.2 9.4 2.5 1.5 1 0 0 1 1 1 0 Tash protein PEST motif Xpo1 PF08389.12 EAN31114.1 - 0.00053 20.1 3.0 0.00053 20.1 3.0 5.0 5 0 0 5 5 5 1 Exportin 1-like protein DUF1825 PF08855.10 EAN31114.1 - 0.028 14.4 0.1 0.069 13.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) SPATA3 PF15662.5 EAN31115.1 - 0.062 13.9 0.0 0.077 13.6 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DUF2115 PF09888.9 EAN31116.1 - 0.053 14.0 0.3 0.5 10.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) SKICH PF17751.1 EAN31118.1 - 0.002 18.7 0.0 0.0075 16.8 0.0 2.0 1 0 0 1 1 1 1 SKICH domain HECW_N PF16562.5 EAN31118.1 - 0.89 9.4 3.7 0.63 9.8 0.1 2.6 3 0 0 3 3 3 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 EF-G-binding_N PF07299.11 EAN31119.1 - 0.02 15.4 5.8 0.021 15.4 3.9 2.0 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal NPHI_C PF08469.10 EAN31119.1 - 0.28 11.1 13.9 0.015 15.3 2.5 2.2 1 1 1 2 2 2 0 Nucleoside triphosphatase I C-terminal ERCC4 PF02732.15 EAN31120.1 - 6.9e-20 71.8 3.7 6.9e-20 71.8 3.7 2.5 3 0 0 3 3 3 1 ERCC4 domain HHH_8 PF14716.6 EAN31120.1 - 3.4e-05 24.1 0.0 0.00011 22.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF86 PF01934.17 EAN31120.1 - 0.011 15.5 0.5 0.049 13.5 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function DUF86 DNA_pol_A_exo1 PF01612.20 EAN31122.1 - 1.8e-41 141.8 0.9 3.6e-41 140.8 0.9 1.6 1 0 0 1 1 1 1 3'-5' exonuclease CooT PF10133.9 EAN31122.1 - 0.026 14.8 0.4 0.088 13.1 0.4 1.9 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT LSM PF01423.22 EAN31123.1 - 7.4e-15 54.4 0.1 9.8e-15 54.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EAN31123.1 - 0.02 14.5 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Hfq protein tRNA-synt_2 PF00152.20 EAN31124.1 - 4.8e-82 275.5 0.0 6.1e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAN31124.1 - 2.3e-11 43.5 0.0 4.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EAN31124.1 - 5.3e-10 39.2 0.1 1e-05 25.1 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) DUF4602 PF15375.6 EAN31125.1 - 2.8e-06 27.7 14.6 1.9e-05 25.0 14.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) CTD_bind PF04818.13 EAN31128.1 - 0.039 14.8 2.8 0.11 13.4 1.5 2.5 2 1 0 2 2 2 0 RNA polymerase II-binding domain. NUC173 PF08161.12 EAN31130.1 - 4.6e-07 29.7 0.1 2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 NUC173 domain FAM176 PF14851.6 EAN31130.1 - 1.5 8.5 9.2 0.73 9.5 2.0 2.4 2 0 0 2 2 2 0 FAM176 family HA2 PF04408.23 EAN31131.1 - 8.1e-20 71.1 0.0 2e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAN31131.1 - 1.7e-14 53.9 0.0 4.2e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAN31131.1 - 2.4e-11 43.9 0.0 7.8e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAN31131.1 - 3.7e-05 23.6 0.4 0.00017 21.4 0.4 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EAN31131.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAN31131.1 - 0.0019 18.5 0.5 0.0092 16.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 EAN31131.1 - 0.0076 16.3 0.0 6 6.8 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAN31131.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 EAN31131.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain T2SSE PF00437.20 EAN31131.1 - 0.027 13.5 0.1 0.074 12.1 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 EAN31131.1 - 0.028 13.8 0.1 0.078 12.3 0.1 1.8 1 0 0 1 1 1 0 KaiC SRP54 PF00448.22 EAN31131.1 - 0.038 13.6 0.1 0.13 11.9 0.0 2.0 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 EAN31131.1 - 0.11 12.7 0.4 5.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EAN31131.1 - 1.1 9.7 13.9 1.4 9.4 0.0 3.4 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 EAN31131.1 - 1.6 9.2 4.4 0.56 10.7 0.1 2.6 3 1 0 3 3 2 0 ABC transporter ERCC4 PF02732.15 EAN31132.1 - 6.9e-17 62.1 0.0 6.9e-17 62.1 0.0 3.3 2 1 0 2 2 2 1 ERCC4 domain Vps36_ESCRT-II PF11605.8 EAN31133.1 - 0.00096 19.3 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Gaa1 PF04114.14 EAN31134.1 - 5.1e-24 85.2 27.0 1.3e-21 77.3 11.2 3.8 3 1 0 3 3 3 2 Gaa1-like, GPI transamidase component SHR3_chaperone PF08229.11 EAN31134.1 - 0.062 12.3 2.8 0.72 8.8 0.0 2.9 3 0 0 3 3 3 0 ER membrane protein SH3 Brix PF04427.18 EAN31135.1 - 1.6e-26 93.6 0.3 2.5e-26 93.0 0.3 1.3 1 0 0 1 1 1 1 Brix domain FAINT PF04385.15 EAN31137.1 - 0.1 12.6 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function, DUF529 DUF2185 PF09951.9 EAN31138.1 - 0.01 15.6 0.7 0.024 14.4 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) Flavodoxin_1 PF00258.25 EAN31138.1 - 1.2 9.3 4.7 1 9.6 2.6 1.8 1 1 1 2 2 2 0 Flavodoxin Pap_E4 PF02711.14 EAN31138.1 - 2.1 9.3 5.0 2.5 9.1 0.7 2.5 2 1 1 3 3 3 0 E4 protein PPR_2 PF13041.6 EAN31139.1 - 1.2e-67 223.9 19.3 1.1e-16 60.7 0.0 8.1 2 1 6 8 8 8 8 PPR repeat family PPR_3 PF13812.6 EAN31139.1 - 7e-56 186.2 11.4 4.2e-16 58.8 0.2 6.0 3 1 4 7 7 7 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 EAN31139.1 - 2.3e-53 177.6 8.1 4.2e-10 39.2 0.0 9.0 10 0 0 10 10 10 8 PPR repeat PPR PF01535.20 EAN31139.1 - 7.1e-51 167.0 22.1 5e-08 32.7 0.0 10.2 10 0 0 10 10 10 7 PPR repeat PPR_long PF17177.4 EAN31139.1 - 7.4e-24 84.3 0.0 4.1e-15 55.7 0.0 4.9 3 2 2 5 5 5 5 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 EAN31139.1 - 2.6e-09 36.9 0.9 0.26 11.2 0.0 5.6 2 2 2 5 5 5 3 Mitochondrial ATPase expression RPM2 PF08579.11 EAN31139.1 - 0.0024 18.3 6.7 0.088 13.2 0.1 5.1 4 2 2 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 EAN31139.1 - 0.0075 15.2 1.8 0.36 9.7 0.0 3.7 4 1 1 5 5 5 1 Mitochondrial 28S ribosomal protein S27 COX5A PF02284.16 EAN31139.1 - 0.052 13.6 0.1 5.2 7.1 0.0 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Va MNE1 PF13762.6 EAN31139.1 - 0.81 9.7 7.9 24 4.9 0.4 4.8 3 3 1 4 4 4 0 Mitochondrial splicing apparatus component DUF1722 PF08349.11 EAN31140.1 - 0.0028 17.9 0.1 0.014 15.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1722) zf-HC3 PF16827.5 EAN31140.1 - 2 8.7 6.2 10 6.4 0.6 2.4 1 1 1 2 2 2 0 zinc-finger DUF3552 PF12072.8 EAN31140.1 - 4.3 6.7 6.3 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) YnfE PF17452.2 EAN31142.1 - 0.46 10.8 3.7 1 9.7 3.7 1.5 1 0 0 1 1 1 0 Uncharacterized YnfE-like TFIIA PF03153.13 EAN31142.1 - 5.5 6.9 35.8 0.19 11.7 25.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BT1 PF03092.16 EAN31143.1 - 5e-53 180.1 20.5 1.4e-35 122.5 8.2 2.1 2 0 0 2 2 2 2 BT1 family Band_7 PF01145.25 EAN31144.1 - 4.8e-25 88.6 0.3 8.4e-25 87.8 0.2 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EAN31144.1 - 0.00046 19.3 2.5 0.0006 19.0 2.5 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial 60KD_IMP PF02096.20 EAN31145.1 - 7.9e-11 42.1 0.6 7.9e-11 42.1 0.6 1.7 2 1 0 2 2 2 1 60Kd inner membrane protein Beach PF02138.18 EAN31146.1 - 8e-92 307.5 0.1 3.5e-91 305.4 0.1 1.9 1 1 0 1 1 1 1 Beige/BEACH domain Arm_3 PF16186.5 EAN31146.1 - 0.34 10.5 1.7 0.96 9.1 1.7 1.7 1 0 0 1 1 1 0 Atypical Arm repeat BBS2_Mid PF14783.6 EAN31147.1 - 0.015 15.3 0.0 0.041 13.9 0.0 1.7 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region ERO1 PF04137.15 EAN31148.1 - 9.2e-69 232.3 4.8 9.2e-69 232.3 4.8 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Tim17 PF02466.19 EAN31149.1 - 1.1e-05 25.8 0.1 1.4e-05 25.5 0.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PIG-F PF06699.11 EAN31149.1 - 0.059 13.5 0.2 0.45 10.7 0.0 1.9 1 1 1 2 2 2 0 GPI biosynthesis protein family Pig-F Methyltransf_11 PF08241.12 EAN31150.1 - 8.7e-14 52.0 0.0 1.1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAN31150.1 - 5.5e-12 46.2 0.0 7.2e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAN31150.1 - 4.4e-09 36.4 0.0 5.8e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAN31150.1 - 8.9e-08 31.8 0.0 1.1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EAN31150.1 - 3.3e-05 23.7 0.0 4.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAN31150.1 - 0.00061 20.5 0.0 0.00086 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EAN31150.1 - 0.083 12.7 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase ubiquitin PF00240.23 EAN31151.1 - 2.8e-21 75.0 0.0 5.1e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAN31151.1 - 1e-06 28.5 0.0 2.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAN31151.1 - 1.6e-06 28.5 0.2 1.6e-06 28.5 0.2 2.5 3 0 0 3 3 3 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EAN31151.1 - 0.00041 20.2 0.1 0.0014 18.5 0.1 1.9 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAN31151.1 - 0.011 15.8 0.1 0.042 13.9 0.0 2.1 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like tRNA-synt_1 PF00133.22 EAN31153.1 - 2.7e-34 118.4 9.1 4.9e-21 74.6 1.0 4.9 3 2 1 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EAN31153.1 - 9e-30 103.7 0.7 4.8e-19 68.4 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EAN31153.1 - 2.7e-09 37.2 0.8 8.1e-09 35.6 0.8 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EAN31153.1 - 0.0018 17.7 0.2 0.14 11.5 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain LSM PF01423.22 EAN31155.1 - 7.4e-16 57.6 0.0 8.6e-16 57.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain 2OG-FeII_Oxy_3 PF13640.6 EAN31156.1 - 1.6e-09 38.5 0.0 2.7e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Thioredoxin PF00085.20 EAN31157.1 - 3.1e-44 149.2 0.5 3.1e-27 94.6 0.1 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EAN31157.1 - 2e-27 96.3 7.7 5.8e-16 58.9 1.1 4.9 4 1 1 5 5 5 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAN31157.1 - 5.6e-11 42.6 6.1 0.00035 20.9 0.1 4.8 4 1 1 5 5 5 2 Thioredoxin-like OST3_OST6 PF04756.13 EAN31157.1 - 1.7e-10 40.8 3.5 3.6e-06 26.5 0.1 3.6 3 1 1 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EAN31157.1 - 1.8e-10 41.2 3.7 6.4e-06 26.6 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EAN31157.1 - 1e-09 38.5 0.2 0.00012 22.1 0.1 2.9 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EAN31157.1 - 1.2e-06 28.5 0.4 0.0012 18.8 0.0 3.0 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 EAN31157.1 - 0.011 15.5 0.7 0.38 10.5 0.1 2.7 3 0 0 3 3 3 0 Redoxin TraF PF13728.6 EAN31157.1 - 0.042 13.7 0.0 2.7 7.7 0.0 2.7 2 0 0 2 2 2 0 F plasmid transfer operon protein HyaE PF07449.11 EAN31157.1 - 0.047 13.7 0.0 0.73 9.8 0.0 2.8 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Prenyltransf PF01255.19 EAN31158.1 - 4.1e-61 206.4 0.0 5e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase FAINT PF04385.15 EAN31159.1 - 0.00058 19.9 18.7 0.0033 17.5 0.1 4.0 3 1 1 4 4 4 2 Domain of unknown function, DUF529 DNA_primase_lrg PF04104.14 EAN31161.1 - 6.9e-80 268.3 0.3 1.2e-79 267.5 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit ParA PF10609.9 EAN31162.1 - 1.3e-69 234.4 0.2 1.7e-69 234.0 0.2 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EAN31162.1 - 4.2e-12 46.2 0.0 7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EAN31162.1 - 3.8e-10 40.0 0.1 3e-09 37.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 EAN31162.1 - 7.5e-09 35.2 0.0 1.8e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EAN31162.1 - 8.4e-08 31.7 1.9 5.3e-05 22.5 0.1 3.0 1 1 2 3 3 3 2 Anion-transporting ATPase CBP_BcsQ PF06564.12 EAN31162.1 - 0.00023 20.8 0.1 0.0034 16.9 0.1 2.2 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 EAN31162.1 - 0.00061 19.7 0.1 0.0019 18.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EAN31162.1 - 0.0014 18.1 0.1 0.032 13.7 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 EAN31162.1 - 0.0018 17.3 0.1 0.0026 16.8 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB VirC1 PF07015.11 EAN31162.1 - 0.0039 16.5 0.0 0.01 15.2 0.0 1.7 2 1 1 3 3 3 1 VirC1 protein AAA_25 PF13481.6 EAN31162.1 - 0.0074 15.9 0.1 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 EAN31162.1 - 0.019 14.9 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 EAN31162.1 - 0.079 12.1 0.1 0.17 11.1 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain Hpr_kinase_C PF07475.12 EAN31162.1 - 0.12 11.9 0.1 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_30 PF13604.6 EAN31162.1 - 0.2 11.3 0.0 0.99 9.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EAN31162.1 - 0.23 12.0 0.4 0.53 10.8 0.1 1.8 2 1 0 2 2 2 0 AAA domain MORN PF02493.20 EAN31163.1 - 2.4e-06 27.1 10.0 0.00045 20.0 4.2 2.9 3 0 0 3 3 3 2 MORN repeat MORN PF02493.20 EAN31164.1 - 3.2e-11 42.4 12.6 0.001 18.8 2.8 4.4 4 0 0 4 4 4 4 MORN repeat Ribosomal_S28e PF01200.18 EAN31165.1 - 2.8e-32 110.5 1.0 3.1e-32 110.4 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S4 PF00163.19 EAN31166.1 - 5.6e-09 36.8 2.0 9e-09 36.1 1.9 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EAN31166.1 - 1.6e-08 34.1 0.0 4.8e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 S4 domain GTP_EFTU_D2 PF03144.25 EAN31166.1 - 0.025 15.0 0.0 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Mac-1 PF09028.10 EAN31166.1 - 0.032 13.3 0.1 0.041 12.9 0.1 1.1 1 0 0 1 1 1 0 Mac 1 RNase_T PF00929.24 EAN31166.1 - 0.051 14.1 2.3 1.1 9.8 0.1 2.2 2 0 0 2 2 2 0 Exonuclease RBFA PF02033.18 EAN31167.1 - 1.4e-13 51.2 0.5 6.8e-13 49.0 0.1 2.4 2 0 0 2 2 2 1 Ribosome-binding factor A Mito_carr PF00153.27 EAN31168.1 - 1.5e-27 95.3 1.6 1.7e-20 72.7 0.4 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Rep_fac_C PF08542.11 EAN31169.1 - 1e-18 67.5 0.1 3.2e-18 65.9 0.1 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EAN31169.1 - 3.9e-16 59.7 0.0 9.8e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EAN31169.1 - 3.4e-13 49.7 0.2 5.1e-11 42.6 0.5 2.4 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 EAN31169.1 - 6.8e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAN31169.1 - 2.1e-06 28.1 0.3 0.0024 18.1 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EAN31169.1 - 2.3e-06 28.1 0.1 0.00034 21.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EAN31169.1 - 4.1e-06 26.8 0.0 1.8e-05 24.7 0.0 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 EAN31169.1 - 9.8e-06 25.4 0.1 6.1e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EAN31169.1 - 2.2e-05 24.4 0.0 3.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EAN31169.1 - 4.1e-05 23.6 0.0 0.00012 22.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EAN31169.1 - 5.3e-05 22.8 0.0 9.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 EAN31169.1 - 6e-05 22.9 0.0 0.002 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAN31169.1 - 0.00012 22.5 0.1 0.00068 20.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EAN31169.1 - 0.00024 20.5 0.0 0.0028 17.0 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EAN31169.1 - 0.00047 20.7 0.0 0.0013 19.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 EAN31169.1 - 0.00052 19.8 0.0 0.0009 19.0 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_assoc_2 PF16193.5 EAN31169.1 - 0.0011 19.2 0.0 0.0038 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain NTPase_1 PF03266.15 EAN31169.1 - 0.0012 18.8 0.6 0.71 9.8 0.1 2.6 1 1 0 2 2 2 1 NTPase AAA_3 PF07726.11 EAN31169.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EAN31169.1 - 0.0023 17.3 0.0 0.2 11.1 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 EAN31169.1 - 0.0036 17.7 0.0 0.024 15.0 0.0 2.2 1 1 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 EAN31169.1 - 0.0048 16.5 0.1 0.018 14.6 0.1 1.9 1 1 0 2 2 2 1 AAA domain MCM PF00493.23 EAN31169.1 - 0.0052 15.9 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_30 PF13604.6 EAN31169.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EAN31169.1 - 0.0067 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DNA_pol3_delta PF06144.13 EAN31169.1 - 0.0069 16.2 0.3 0.012 15.4 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit IstB_IS21 PF01695.17 EAN31169.1 - 0.0075 16.0 0.0 0.018 14.7 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EAN31169.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DUF815 PF05673.13 EAN31169.1 - 0.013 14.7 0.0 0.03 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 EAN31169.1 - 0.015 15.5 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EAN31169.1 - 0.017 14.9 1.4 2.2 8.0 0.0 3.2 2 2 1 3 3 3 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 EAN31169.1 - 0.032 13.6 0.0 0.09 12.1 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.6 EAN31169.1 - 0.046 13.9 0.0 0.2 11.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain SRP54 PF00448.22 EAN31169.1 - 0.074 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 EAN31169.1 - 0.18 12.0 0.1 0.35 11.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EAN31170.1 - 1e-29 103.6 0.1 2.2e-29 102.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN31170.1 - 6.3e-19 68.4 0.0 2.5e-18 66.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN31170.1 - 8.8e-08 32.3 1.5 5.6e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAN31170.1 - 0.0046 17.2 0.6 0.044 14.1 0.2 2.7 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 EAN31170.1 - 0.046 13.6 0.1 0.099 12.6 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 EAN31170.1 - 0.52 10.0 0.0 0.52 10.0 0.0 2.9 2 2 1 3 3 3 0 AAA domain TPR_1 PF00515.28 EAN31171.1 - 3.7e-15 55.0 5.0 4e-06 26.4 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAN31171.1 - 4.7e-15 54.4 4.9 0.00013 21.8 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAN31171.1 - 5.5e-09 36.2 1.8 3.3e-07 30.5 0.2 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAN31171.1 - 6.5e-08 32.1 2.3 0.0036 17.0 0.1 3.6 3 0 0 3 3 3 3 TPR repeat TPR_8 PF13181.6 EAN31171.1 - 5.4e-06 26.2 6.4 0.25 11.7 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAN31171.1 - 5.2e-05 23.0 0.8 0.19 11.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat SPO22 PF08631.10 EAN31171.1 - 0.023 14.2 1.0 0.045 13.2 0.1 1.8 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 EAN31171.1 - 0.035 14.9 0.2 47 5.2 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EAN31171.1 - 0.038 14.1 1.2 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 EAN31171.1 - 0.15 12.2 0.1 0.99 9.6 0.1 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat Sel1 PF08238.12 EAN31171.1 - 0.17 12.6 0.1 0.49 11.1 0.1 1.8 1 0 0 1 1 1 0 Sel1 repeat DUF3597 PF12200.8 EAN31171.1 - 0.17 12.4 1.7 7.2 7.2 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3597) Mnd1 PF03962.15 EAN31172.1 - 6e-13 48.9 4.3 6.3e-13 48.8 0.1 2.2 2 0 0 2 2 2 1 Mnd1 HTH domain SpoOE-like PF09388.10 EAN31172.1 - 0.021 14.7 2.9 0.022 14.6 0.2 2.4 2 1 0 2 2 2 0 Spo0E like sporulation regulatory protein FtsL PF04999.13 EAN31172.1 - 0.042 13.8 0.7 0.083 12.9 0.5 1.5 1 1 0 1 1 1 0 Cell division protein FtsL EF-hand_3 PF09069.11 EAN31172.1 - 0.06 13.8 0.1 0.084 13.3 0.1 1.4 1 1 0 1 1 1 0 EF-hand DUF536 PF04394.14 EAN31172.1 - 0.35 10.8 6.5 0.9 9.4 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF536 YabA PF06156.13 EAN31172.1 - 1 10.0 7.0 3.2 8.5 3.1 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF382 PF04037.13 EAN31173.1 - 2.1e-52 176.6 3.2 2.1e-52 176.6 3.2 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 EAN31173.1 - 7.4e-22 77.0 4.2 1.9e-21 75.6 2.9 2.3 2 0 0 2 2 2 1 PSP UPF0172 PF03665.13 EAN31173.1 - 0.037 14.1 0.7 0.1 12.6 0.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF4298 PF14131.6 EAN31176.1 - 0.014 15.3 8.5 0.69 9.9 0.1 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4298) ADIP PF11559.8 EAN31176.1 - 0.58 10.2 5.6 2.4 8.2 1.1 3.4 4 1 0 4 4 4 0 Afadin- and alpha -actinin-Binding CHCH PF06747.13 EAN31177.1 - 0.019 15.1 1.6 0.03 14.5 1.6 1.4 1 0 0 1 1 1 0 CHCH domain Colipase-like PF15083.6 EAN31177.1 - 0.031 14.4 1.6 0.037 14.2 1.6 1.1 1 0 0 1 1 1 0 Colipase-like DUF1690 PF07956.11 EAN31177.1 - 0.18 12.2 3.2 0.21 12.0 3.2 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) TIP49 PF06068.13 EAN31180.1 - 7.5e-156 518.7 0.1 9.1e-156 518.4 0.1 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EAN31180.1 - 2.9e-20 72.1 1.7 5.2e-20 71.3 0.1 2.3 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EAN31180.1 - 3.4e-09 37.2 0.4 1.9e-06 28.3 0.1 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAN31180.1 - 1.8e-07 31.5 0.1 0.0067 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EAN31180.1 - 2.2e-07 30.8 0.5 0.00084 19.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EAN31180.1 - 6.8e-07 28.9 0.6 0.00016 21.2 0.2 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAN31180.1 - 1.7e-05 24.8 0.1 0.0028 17.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 EAN31180.1 - 2.5e-05 23.8 0.2 4.7e-05 22.9 0.1 1.5 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 EAN31180.1 - 4.1e-05 22.9 0.0 8.7e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.26 EAN31180.1 - 4.7e-05 23.2 0.1 0.11 12.2 0.1 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 EAN31180.1 - 0.00013 22.4 0.1 0.00043 20.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 EAN31180.1 - 0.0002 21.8 0.0 0.00072 20.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain CPT PF07931.12 EAN31180.1 - 0.00021 21.2 0.0 0.005 16.7 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 EAN31180.1 - 0.00036 20.9 1.2 0.015 15.7 1.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAN31180.1 - 0.00098 19.7 0.0 0.0026 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAN31180.1 - 0.0022 17.6 0.0 0.0077 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EAN31180.1 - 0.0025 17.5 0.4 0.47 10.2 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 EAN31180.1 - 0.015 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 EAN31180.1 - 0.018 14.6 0.1 0.14 11.7 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF2075 PF09848.9 EAN31180.1 - 0.019 14.2 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EAN31180.1 - 0.035 13.5 0.7 0.064 12.6 0.7 1.6 1 1 0 1 1 1 0 KaiC AAA_30 PF13604.6 EAN31180.1 - 0.051 13.3 0.3 2.7 7.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EAN31180.1 - 0.053 13.6 0.6 0.27 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EAN31180.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EAN31180.1 - 0.076 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase ResIII PF04851.15 EAN31180.1 - 0.076 13.0 0.1 3.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 EAN31180.1 - 0.078 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EAN31180.1 - 0.085 13.2 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 EAN31180.1 - 0.093 13.2 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EAN31180.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PIF1 PF05970.14 EAN31180.1 - 0.14 11.3 0.3 15 4.7 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase T2SSE PF00437.20 EAN31180.1 - 0.9 8.5 3.1 5 6.1 0.1 2.7 2 1 1 3 3 3 0 Type II/IV secretion system protein EMC3_TMCO1 PF01956.16 EAN31181.1 - 1.6e-25 89.8 0.2 2e-25 89.5 0.2 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SBP_bac_1 PF01547.25 EAN31181.1 - 0.22 11.4 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein PCNA_N PF00705.18 EAN31182.1 - 4.5e-43 146.0 2.1 4.5e-43 146.0 2.1 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EAN31182.1 - 3.8e-27 95.0 0.0 6.8e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain DNA_pol3_beta_2 PF02767.16 EAN31182.1 - 0.14 12.4 0.4 0.27 11.4 0.1 1.6 2 0 0 2 2 2 0 DNA polymerase III beta subunit, central domain Proteasome PF00227.26 EAN31183.1 - 6.6e-30 104.0 0.0 7.7e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit NAP PF00956.18 EAN31184.1 - 4.7e-62 209.6 10.6 1.7e-60 204.5 10.6 2.0 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) FCH PF00611.23 EAN31184.1 - 0.0068 16.7 0.1 0.016 15.5 0.1 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Mst1_SARAH PF11629.8 EAN31184.1 - 0.049 13.7 3.7 0.069 13.2 1.6 2.3 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 UQ_con PF00179.26 EAN31185.1 - 2.9e-54 182.5 0.1 3.3e-54 182.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAN31185.1 - 0.00019 21.2 0.0 0.00024 20.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EAN31185.1 - 0.012 15.9 0.1 0.014 15.6 0.1 1.3 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 EAN31185.1 - 0.018 14.9 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 UEV domain RNA_pol_Rpb1_1 PF04997.12 EAN31186.1 - 0.021 14.2 1.4 0.025 13.9 1.4 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 DUF262 PF03235.14 EAN31186.1 - 0.057 13.6 5.4 0.067 13.4 5.0 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF262 SipA_VBS PF17985.1 EAN31186.1 - 0.22 11.5 1.5 3.6 7.7 0.2 2.7 3 0 0 3 3 3 0 SipA vinculin binding site DUF726 PF05277.12 EAN31187.1 - 3.6e-68 230.0 0.5 2.9e-58 197.4 0.3 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF726) VirJ PF06057.11 EAN31187.1 - 0.045 13.6 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Cutinase PF01083.22 EAN31187.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Cutinase Myb_DNA-bind_7 PF15963.5 EAN31188.1 - 6.2e-23 80.5 1.7 6.2e-23 80.5 1.7 3.0 3 0 0 3 3 3 1 Myb DNA-binding like TA0956 PF11513.8 EAN31188.1 - 3.8 7.8 9.0 2.8 8.2 0.1 3.6 4 0 0 4 4 4 0 Thermoplasma acidophilum protein TA0956 TPR_1 PF00515.28 EAN31189.1 - 7.1e-10 38.3 0.0 0.0086 15.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAN31189.1 - 9.6e-10 37.8 0.1 0.045 13.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat SHNi-TPR PF10516.9 EAN31189.1 - 1.5e-08 34.0 0.6 5.4e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 EAN31189.1 - 2.2e-07 31.0 0.3 0.00055 20.2 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAN31189.1 - 9.6e-05 22.3 2.0 0.67 10.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAN31189.1 - 0.00062 19.9 1.1 0.05 13.8 0.1 3.1 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TBCC_N PF16752.5 EAN31189.1 - 0.00096 19.6 1.8 0.0038 17.6 1.8 2.1 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain TruD PF01142.18 EAN31189.1 - 0.001 18.0 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) TPR_MalT PF17874.1 EAN31189.1 - 0.0023 17.4 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_19 PF14559.6 EAN31189.1 - 0.099 13.2 0.5 7.9 7.1 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EAN31189.1 - 0.13 12.3 5.4 4 7.6 0.3 3.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain CactinC_cactus PF09732.9 EAN31190.1 - 4.8e-48 162.2 5.8 8.2e-48 161.5 5.8 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Lipase3_N PF03893.16 EAN31190.1 - 0.064 13.3 2.2 0.17 11.9 0.0 2.5 2 1 1 3 3 3 0 Lipase 3 N-terminal region Cactin_mid PF10312.9 EAN31191.1 - 0.00035 20.4 0.0 0.00035 20.4 0.0 2.4 1 1 1 2 2 2 1 Conserved mid region of cactin UPF0158 PF03682.13 EAN31191.1 - 0.057 13.4 3.3 0.065 13.2 2.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0158) YukC PF10140.9 EAN31192.1 - 0.015 14.2 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF1129 PF06570.11 EAN31192.1 - 0.38 10.2 1.8 0.82 9.1 0.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) dCMP_cyt_deam_1 PF00383.23 EAN31193.1 - 4.1e-12 45.9 1.1 8.2e-12 44.9 1.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EAN31193.1 - 3.9e-11 42.9 1.5 1.8e-10 40.7 1.5 2.0 1 1 0 1 1 1 1 MafB19-like deaminase FHA PF00498.26 EAN31197.1 - 6.8e-17 61.6 5.2 1.1e-08 35.2 0.5 3.3 4 0 0 4 4 3 2 FHA domain zf-C3HC4_4 PF15227.6 EAN31197.1 - 6.4e-09 35.8 11.0 1.3e-08 34.8 11.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EAN31197.1 - 1.4e-08 34.4 5.0 2.3e-08 33.7 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN31197.1 - 3.4e-08 33.4 4.9 3.4e-08 33.4 4.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAN31197.1 - 6.1e-08 32.4 8.9 1.1e-07 31.5 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAN31197.1 - 1.5e-06 28.5 8.2 3e-06 27.5 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAN31197.1 - 2e-06 27.6 8.1 3.9e-06 26.6 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAN31197.1 - 0.00018 21.3 6.0 0.00051 19.8 6.0 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EAN31197.1 - 0.00029 20.7 8.9 0.00056 19.8 8.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 EAN31197.1 - 0.0029 17.7 3.0 0.0066 16.6 3.0 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EAN31197.1 - 0.016 15.0 2.5 0.016 15.0 2.5 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EAN31197.1 - 0.079 13.3 6.6 0.24 11.7 6.7 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EAN31197.1 - 0.09 12.7 3.9 0.21 11.5 3.9 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 EAN31197.1 - 0.09 12.6 1.7 0.22 11.4 1.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Peptidase_M24 PF00557.24 EAN31203.1 - 2.5e-38 131.9 0.0 3.4e-18 66.1 0.0 2.3 2 1 0 2 2 2 2 Metallopeptidase family M24 YwpF PF14183.6 EAN31205.1 - 0.0087 16.1 2.1 0.011 15.7 0.5 1.9 2 0 0 2 2 2 1 YwpF-like protein Popeye PF04831.13 EAN31209.1 - 0.00099 19.3 0.1 0.0023 18.1 0.1 1.6 1 0 0 1 1 1 1 Popeye protein conserved region Rav1p_C PF12234.8 EAN31210.1 - 2e-22 79.4 7.4 3.1e-20 72.2 2.9 4.1 4 0 0 4 4 4 3 RAVE protein 1 C terminal IL12p40_C PF10420.9 EAN31210.1 - 8.3 7.0 9.6 11 6.6 0.0 3.9 4 0 0 4 4 4 0 Cytokine interleukin-12p40 C-terminus NFACT-R_1 PF05670.13 EAN31211.1 - 1.2e-28 100.0 0.0 1.2e-28 100.0 0.0 2.4 2 0 0 2 2 2 1 NFACT protein RNA binding domain FbpA PF05833.11 EAN31211.1 - 2e-23 82.9 20.2 1.9e-18 66.5 1.2 3.4 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 EAN31211.1 - 9.6e-15 54.4 0.0 9.6e-15 54.4 0.0 4.0 4 1 0 4 4 4 1 NFACT protein C-terminal domain 60KD_IMP PF02096.20 EAN31211.1 - 9.2 6.1 10.0 62 3.4 10.0 2.3 1 1 0 1 1 1 0 60Kd inner membrane protein TRAUB PF08164.12 EAN31212.1 - 5.1e-06 26.9 1.5 5.1e-06 26.9 1.5 2.0 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EAN31212.1 - 0.0053 17.4 0.7 0.0053 17.4 0.7 1.9 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor HeLo PF14479.6 EAN31212.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation HMG_box PF00505.19 EAN31213.1 - 2.2e-24 85.6 1.2 2.2e-24 85.6 1.2 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAN31213.1 - 2.3e-15 57.0 1.7 3.7e-15 56.3 1.7 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 EAN31213.1 - 0.024 14.6 1.6 0.034 14.1 0.9 1.8 1 1 0 1 1 1 0 HMG (high mobility group) box 5 DUF2582 PF10771.9 EAN31213.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) AAA_22 PF13401.6 EAN31214.1 - 1.4e-11 44.8 0.0 3.3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EAN31214.1 - 2e-11 44.4 0.0 1e-10 42.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAN31214.1 - 1.2e-07 32.2 0.0 4.6e-05 23.9 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_lid_10 PF17872.1 EAN31214.1 - 0.00022 21.3 0.1 0.0006 19.9 0.1 1.7 1 0 0 1 1 1 1 AAA lid domain Rad17 PF03215.15 EAN31214.1 - 0.001 19.0 0.0 0.0032 17.4 0.0 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain NACHT PF05729.12 EAN31214.1 - 0.0011 19.0 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 EAN31214.1 - 0.0039 17.2 0.2 0.018 15.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAN31214.1 - 0.01 16.2 0.6 0.12 12.7 0.6 2.2 2 0 0 2 2 2 1 AAA domain Lipase_bact_N PF12262.8 EAN31214.1 - 0.015 14.6 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal MeaB PF03308.16 EAN31214.1 - 0.023 13.7 0.2 0.041 12.9 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EAN31214.1 - 0.035 13.8 0.0 0.092 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain SRP14 PF02290.15 EAN31217.1 - 8.7e-13 48.5 0.0 1e-12 48.2 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Sua5_yciO_yrdC PF01300.18 EAN31218.1 - 6.3e-40 136.6 0.0 1e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EAN31218.1 - 0.0018 18.8 0.0 0.0033 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DZR PF12773.7 EAN31219.1 - 0.4 10.7 3.9 9.8 6.3 0.5 2.9 2 1 1 3 3 3 0 Double zinc ribbon HNH_5 PF14279.6 EAN31219.1 - 0.5 10.3 6.0 27 4.7 0.1 3.4 3 0 0 3 3 3 0 HNH endonuclease Med6 PF04934.14 EAN31220.1 - 7.7e-20 71.1 1.0 1.2e-19 70.4 1.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component FAINT PF04385.15 EAN31221.1 - 7.7e-05 22.7 0.7 0.29 11.2 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function, DUF529 DEAD PF00270.29 EAN31222.1 - 9.6e-48 162.3 0.0 2.1e-47 161.2 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN31222.1 - 1.1e-32 112.6 0.1 2e-31 108.6 0.1 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EAN31222.1 - 0.0019 17.4 0.1 0.0044 16.2 0.1 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Collagen PF01391.18 EAN31222.1 - 1.1 9.1 4.0 0.84 9.4 1.4 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) TraG-D_C PF12696.7 EAN31222.1 - 7.3 6.6 9.4 2 8.4 4.7 2.5 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG PhoLip_ATPase_C PF16212.5 EAN31223.1 - 1.7e-57 195.0 20.3 1.7e-57 195.0 20.3 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAN31223.1 - 6.2e-18 64.3 1.7 2.6e-17 62.2 1.7 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EAN31223.1 - 8.6e-05 22.1 0.0 0.0015 18.1 0.0 3.6 4 1 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 EAN31223.1 - 0.00018 21.9 0.0 0.023 15.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Clathrin PF00637.20 EAN31224.1 - 2.5e-114 377.5 94.2 4.5e-24 85.0 1.5 9.2 8 1 1 9 9 9 8 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EAN31224.1 - 2e-20 72.5 0.8 1.2e-19 70.0 0.2 2.7 3 0 0 3 3 3 1 Clathrin-H-link TPR_2 PF07719.17 EAN31224.1 - 4.8e-05 23.2 8.4 0.1 12.7 0.1 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat Clathrin_propel PF01394.20 EAN31224.1 - 6.1e-05 23.1 0.2 0.32 11.4 0.0 3.1 2 0 0 2 2 2 2 Clathrin propeller repeat TPR_1 PF00515.28 EAN31224.1 - 0.0016 18.1 13.4 1.1 9.2 0.1 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAN31224.1 - 0.007 16.5 15.0 1.2 9.5 0.1 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat Ovate PF04844.13 EAN31224.1 - 0.011 15.7 3.8 0.79 9.8 0.2 3.1 2 0 0 2 2 2 0 Transcriptional repressor, ovate Ssl1 PF04056.14 EAN31225.1 - 5.5e-46 156.8 0.0 3.3e-37 128.2 0.0 2.1 2 0 0 2 2 2 2 Ssl1-like VWA_2 PF13519.6 EAN31225.1 - 1.1e-09 38.9 0.0 1.8e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 EAN31225.1 - 0.001 19.3 16.6 0.001 19.3 16.6 3.2 2 2 1 3 3 3 1 TFIIH C1-like domain VWA PF00092.28 EAN31225.1 - 0.024 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain FAINT PF04385.15 EAN31229.1 - 1.3e-32 111.6 28.5 4.2e-09 36.3 0.6 6.1 6 0 0 6 6 6 5 Domain of unknown function, DUF529 Dicty_CAD PF05720.12 EAN31229.1 - 0.0095 15.9 0.5 2.6 8.1 0.0 3.4 3 0 0 3 3 3 1 Cell-cell adhesion domain UPF0182 PF03699.13 EAN31230.1 - 0.36 8.9 2.4 0.44 8.6 2.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Ribosomal_L34e PF01199.18 EAN31232.1 - 3.9e-39 132.8 7.0 3.9e-39 132.8 7.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L34e tRNA-synt_2 PF00152.20 EAN31233.1 - 1.2e-65 221.7 0.9 5e-65 219.6 0.9 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAN31233.1 - 1.4e-08 34.6 0.1 2.7e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EAN31233.1 - 0.0015 18.6 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EAN31233.1 - 0.0024 17.4 0.3 0.39 10.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) LCM PF04072.14 EAN31234.1 - 1.5e-06 28.3 0.0 2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase AAA PF00004.29 EAN31235.1 - 2.5e-90 299.7 0.0 2.1e-45 154.4 0.0 3.3 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAN31235.1 - 7.5e-29 99.3 1.2 5.4e-13 48.5 0.0 3.5 3 0 0 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 EAN31235.1 - 2.6e-14 53.3 0.0 1.3e-05 25.0 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EAN31235.1 - 2.7e-13 50.6 0.0 2.7e-05 24.6 0.0 3.7 3 2 0 3 3 2 2 AAA ATPase domain AAA_2 PF07724.14 EAN31235.1 - 8.1e-12 45.6 0.0 0.00015 22.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EAN31235.1 - 1.7e-11 44.5 0.0 5.3e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EAN31235.1 - 9.9e-11 41.8 0.0 0.00091 19.2 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EAN31235.1 - 5.7e-10 38.9 0.0 0.00081 18.7 0.0 3.1 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_14 PF13173.6 EAN31235.1 - 2.8e-09 37.1 0.0 0.0039 17.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EAN31235.1 - 3.4e-09 37.1 0.5 0.029 14.6 0.0 3.9 2 2 2 4 4 3 2 AAA domain AAA_18 PF13238.6 EAN31235.1 - 5.8e-08 33.4 0.0 0.021 15.4 0.0 3.3 3 0 0 3 3 2 2 AAA domain Viral_helicase1 PF01443.18 EAN31235.1 - 1.7e-07 31.2 0.0 0.0042 16.8 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 EAN31235.1 - 3e-07 30.3 0.0 0.029 14.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 EAN31235.1 - 3.3e-07 30.7 0.0 0.012 16.0 0.0 2.9 2 0 0 2 2 2 2 RNA helicase CDC48_N PF02359.18 EAN31235.1 - 1.4e-06 28.4 0.4 3.7e-06 27.0 0.4 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Mg_chelatase PF01078.21 EAN31235.1 - 1.9e-06 27.4 0.2 0.029 13.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EAN31235.1 - 3.1e-06 27.5 0.0 0.053 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EAN31235.1 - 3.9e-06 26.8 0.0 0.00027 20.9 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.6 EAN31235.1 - 4.2e-06 27.2 0.1 0.07 13.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 EAN31235.1 - 7.5e-06 26.5 0.1 0.26 11.8 0.1 2.8 2 1 0 2 2 2 2 ABC transporter TsaE PF02367.17 EAN31235.1 - 1.1e-05 25.4 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EAN31235.1 - 1.3e-05 25.2 0.0 0.25 11.2 0.0 2.9 2 0 0 2 2 2 2 NACHT domain Bac_DnaA PF00308.18 EAN31235.1 - 1.5e-05 24.9 0.2 0.3 10.9 0.0 3.7 4 0 0 4 4 4 2 Bacterial dnaA protein ATPase_2 PF01637.18 EAN31235.1 - 2.4e-05 24.4 0.3 0.29 11.0 0.0 3.3 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EAN31235.1 - 3.1e-05 23.4 0.0 0.063 12.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_7 PF12775.7 EAN31235.1 - 5.5e-05 22.8 0.0 0.15 11.5 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 EAN31235.1 - 6.6e-05 22.2 0.1 0.38 9.9 0.0 3.0 3 0 0 3 3 3 2 NB-ARC domain Sigma54_activ_2 PF14532.6 EAN31235.1 - 9.7e-05 22.5 0.0 0.64 10.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EAN31235.1 - 0.0002 20.5 0.1 0.034 13.3 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EAN31235.1 - 0.00025 20.8 0.0 1.3 8.7 0.0 3.0 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 EAN31235.1 - 0.00026 20.6 0.0 1.4 8.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 EAN31235.1 - 0.00037 20.4 0.0 0.97 9.3 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EAN31235.1 - 0.00044 19.6 0.0 0.28 10.4 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.6 EAN31235.1 - 0.00054 20.1 0.0 0.63 10.1 0.0 2.8 3 0 0 3 3 2 1 Cytidylate kinase-like family AAA_11 PF13086.6 EAN31235.1 - 0.00089 19.1 0.0 1.2 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 EAN31235.1 - 0.0018 17.7 0.4 4.7 6.5 0.0 3.3 2 1 0 3 3 3 0 KaiC AAA_24 PF13479.6 EAN31235.1 - 0.0018 18.0 0.0 1.9 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EAN31235.1 - 0.0019 18.2 0.0 0.56 10.2 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAN31235.1 - 0.0025 17.3 0.1 1.7 8.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Rad17 PF03215.15 EAN31235.1 - 0.0028 17.6 0.1 1.1 9.1 0.0 2.9 2 1 0 2 2 2 1 Rad17 P-loop domain DUF815 PF05673.13 EAN31235.1 - 0.0043 16.3 0.0 0.18 10.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 EAN31235.1 - 0.0047 16.7 0.2 0.78 9.4 0.0 2.7 3 0 0 3 3 2 1 Cytidylate kinase NTPase_1 PF03266.15 EAN31235.1 - 0.0068 16.3 0.2 18 5.2 0.0 3.8 3 1 1 4 4 3 0 NTPase AAA_19 PF13245.6 EAN31235.1 - 0.0086 16.4 0.2 4.2 7.7 0.2 2.8 2 1 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 EAN31235.1 - 0.014 15.7 5.9 0.24 11.6 0.0 3.7 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain AAA_30 PF13604.6 EAN31235.1 - 0.015 15.0 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EAN31235.1 - 0.026 14.1 0.1 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain SKI PF01202.22 EAN31235.1 - 0.035 14.2 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase DAP3 PF10236.9 EAN31235.1 - 0.057 12.6 0.0 13 4.8 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Torsin PF06309.11 EAN31235.1 - 0.074 13.2 0.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Torsin SRPRB PF09439.10 EAN31235.1 - 0.091 12.2 0.0 14 5.0 0.0 3.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAN31235.1 - 0.12 12.1 0.0 7.9 6.2 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Zot PF05707.12 EAN31235.1 - 0.14 11.8 0.1 1.6 8.3 0.0 2.5 2 1 1 3 3 2 0 Zonular occludens toxin (Zot) Haemadin PF09065.10 EAN31235.1 - 0.15 11.9 0.0 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 Haemadin DNA_mis_repair PF01119.19 EAN31236.1 - 3.5e-25 88.0 0.7 8.4e-25 86.8 0.4 1.8 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 EAN31236.1 - 1.5e-17 63.8 0.0 3.9e-15 55.9 0.0 2.8 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EAN31236.1 - 2.6e-09 37.0 1.4 4.1e-09 36.4 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EAN31236.1 - 1.3e-05 25.7 0.1 4.5e-05 23.9 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Myosin_tail_1 PF01576.19 EAN31237.1 - 0.14 9.9 5.2 0.2 9.4 5.2 1.1 1 0 0 1 1 1 0 Myosin tail USP7_C2 PF14533.6 EAN31238.1 - 1.1e-08 35.1 1.5 1.4e-08 34.7 0.4 1.8 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal Octopine_DH PF02317.17 EAN31238.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain UCH PF00443.29 EAN31239.1 - 5.7e-45 153.8 2.0 6.4e-45 153.7 0.5 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAN31239.1 - 2.9e-15 56.7 0.6 2.9e-08 33.7 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Methyltr_RsmB-F PF01189.17 EAN31241.1 - 6.5e-26 91.2 0.0 1.4e-25 90.2 0.0 1.5 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 EAN31241.1 - 4e-09 36.4 0.1 1.1e-08 35.0 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAN31241.1 - 0.0021 18.7 0.0 0.088 13.5 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAN31241.1 - 0.0053 16.6 0.0 0.1 12.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAN31241.1 - 0.12 13.1 0.0 36 5.2 0.0 3.2 3 0 0 3 3 3 0 Methyltransferase domain Vps51 PF08700.11 EAN31242.1 - 2.6e-18 65.9 1.4 6.9e-18 64.5 1.4 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 EAN31242.1 - 2.4e-05 24.5 1.9 0.00012 22.3 1.9 2.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF2153 PF09921.9 EAN31242.1 - 0.065 13.0 1.2 0.36 10.7 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) Flp_N PF03930.14 EAN31242.1 - 0.79 9.7 6.5 0.53 10.3 0.8 3.6 4 0 0 4 4 4 0 Recombinase Flp protein N-terminus FAINT PF04385.15 EAN31243.1 - 0.0019 18.3 0.7 0.18 11.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Prenyltrans PF00432.21 EAN31245.1 - 1.3e-37 127.2 8.5 3.6e-10 39.4 0.2 6.4 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EAN31245.1 - 0.01 14.9 0.0 9.5 5.2 0.0 3.1 3 0 0 3 3 3 0 Squalene-hopene cyclase N-terminal domain MMR_HSR1 PF01926.23 EAN31247.1 - 2.1e-42 143.8 0.7 8e-21 74.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 EAN31247.1 - 1.1e-26 93.0 0.1 2.8e-26 91.7 0.1 1.8 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 EAN31247.1 - 6.2e-19 68.0 0.1 7.8e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EAN31247.1 - 1.2e-12 47.8 0.6 5.7e-07 29.3 0.2 4.3 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EAN31247.1 - 1.1e-09 38.6 2.8 0.075 13.1 0.1 4.3 2 2 1 4 4 4 3 Dynamin family AIG1 PF04548.16 EAN31247.1 - 1.1e-08 34.6 2.3 0.00051 19.4 0.0 2.9 3 0 0 3 3 3 2 AIG1 family SRPRB PF09439.10 EAN31247.1 - 1.4e-07 31.2 1.3 0.00036 20.0 0.0 2.7 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.22 EAN31247.1 - 6.1e-07 29.2 1.0 0.0033 17.0 0.5 2.6 2 1 0 2 2 2 2 Ras family RsgA_GTPase PF03193.16 EAN31247.1 - 1.2e-06 28.5 0.6 0.58 10.0 0.0 4.0 2 1 1 3 3 3 3 RsgA GTPase Roc PF08477.13 EAN31247.1 - 9e-06 25.9 2.3 0.17 12.1 0.1 3.2 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EAN31247.1 - 0.0066 17.0 0.3 1.1 9.8 0.0 2.7 2 1 0 2 2 2 1 ABC transporter cobW PF02492.19 EAN31247.1 - 0.016 14.8 1.6 0.13 11.9 0.2 2.7 3 1 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EAN31247.1 - 0.052 13.8 0.0 0.4 10.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EAN31247.1 - 0.067 12.9 3.2 0.55 9.9 3.3 2.3 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 EAN31247.1 - 0.19 10.7 0.2 19 4.1 0.1 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB zf-CSL PF05207.13 EAN31248.1 - 7e-17 60.9 1.5 9.5e-17 60.5 1.5 1.2 1 0 0 1 1 1 1 CSL zinc finger YGGT PF02325.17 EAN31249.1 - 0.00024 21.5 4.7 0.00024 21.5 4.7 1.6 2 0 0 2 2 2 1 YGGT family ESCRT-II PF05871.12 EAN31250.1 - 1.2e-14 54.8 0.0 1.5e-13 51.2 0.0 2.1 1 1 0 1 1 1 1 ESCRT-II complex subunit DDRGK PF09756.9 EAN31251.1 - 8.1e-53 178.8 24.2 1e-52 178.5 24.2 1.1 1 0 0 1 1 1 1 DDRGK domain SID-1_RNA_chan PF13965.6 EAN31251.1 - 0.032 12.7 0.4 0.037 12.5 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1150 PF06620.11 EAN31251.1 - 0.091 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) NDUF_B6 PF09782.9 EAN31251.1 - 0.14 12.3 4.1 42 4.2 0.0 2.3 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Atg14 PF10186.9 EAN31251.1 - 0.16 11.0 10.7 0.22 10.6 10.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_S49_N PF08496.10 EAN31251.1 - 0.35 10.9 12.4 0.68 10.0 12.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4554 PF15091.6 EAN31251.1 - 0.93 8.3 5.3 1.4 7.7 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) PA26 PF04636.13 EAN31251.1 - 2.1 7.2 8.3 2.6 6.9 8.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) eIF3_subunit PF08597.10 EAN31251.1 - 2.7 7.8 22.3 3.9 7.3 22.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Cytochrom_C PF00034.21 EAN31251.1 - 3.1 9.0 4.7 41 5.4 4.7 2.5 1 1 0 1 1 1 0 Cytochrome c DUF5401 PF17380.2 EAN31251.1 - 3.6 5.5 26.9 5 5.1 26.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) CLN3 PF02487.17 EAN31251.1 - 5.4 5.9 4.7 5.1 6.0 0.0 2.0 1 1 1 2 2 2 0 CLN3 protein Sec62 PF03839.16 EAN31251.1 - 6.6 6.2 8.2 11 5.4 8.2 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 CENP-H PF05837.12 EAN31251.1 - 8.2 6.9 16.1 36 4.8 0.1 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) PolyA_pol PF01743.20 EAN31252.1 - 6.8e-27 94.4 0.1 1.8e-26 93.0 0.1 1.8 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EAN31252.1 - 1.8e-05 24.4 0.0 3.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Nudc_N PF14050.6 EAN31253.1 - 0.076 13.0 0.2 0.16 11.9 0.2 1.7 1 1 0 1 1 1 0 N-terminal conserved domain of Nudc. DHHC PF01529.20 EAN31255.1 - 6.1e-30 104.1 17.6 6.1e-30 104.1 17.6 2.9 2 1 1 3 3 3 1 DHHC palmitoyltransferase Pkinase PF00069.25 EAN31256.1 - 3.6e-61 206.8 0.0 9.5e-61 205.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 EAN31256.1 - 2.5e-60 200.5 0.6 8.1e-19 67.5 0.0 4.7 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EAN31256.1 - 2.3e-31 109.0 0.0 4.6e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAN31256.1 - 4.3e-06 26.3 0.2 9.2e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAN31256.1 - 0.00043 19.2 0.0 0.00096 18.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAN31256.1 - 0.0049 16.8 0.0 0.0092 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAN31256.1 - 0.0062 15.6 0.0 0.021 13.9 0.0 1.9 2 0 0 2 2 2 1 Seadornavirus VP7 Zip PF02535.22 EAN31258.1 - 1.1e-20 74.2 4.2 1.4e-20 73.8 4.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2852 PF11014.8 EAN31258.1 - 0.081 13.1 0.0 4.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Ribosomal_L3 PF00297.22 EAN31259.1 - 5.3e-13 48.7 5.0 5.7e-12 45.3 5.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 RRM_1 PF00076.22 EAN31260.1 - 1.1e-27 95.7 0.7 1.8e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAN31260.1 - 1.6e-06 28.1 3.2 0.037 14.1 0.0 3.1 4 0 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EAN31260.1 - 1.3e-05 25.1 0.4 0.037 14.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 EAN31260.1 - 0.025 14.5 0.2 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 RL domain CSD PF00313.22 EAN31260.1 - 1.4 8.9 3.4 26 4.8 0.3 2.6 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Dicty_REP PF05086.12 EAN31260.1 - 2.7 5.9 11.7 3.4 5.5 11.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_memb PF02932.16 EAN31260.1 - 3.1 7.8 4.5 5.5 7.0 4.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 EAN31260.1 - 5.2 5.7 6.6 7.7 5.2 6.6 1.2 1 0 0 1 1 1 0 Presenilin Mitofilin PF09731.9 EAN31260.1 - 5.9 5.6 13.6 7.9 5.2 13.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LSM PF01423.22 EAN31261.1 - 2.9e-15 55.7 0.0 4.6e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAN31261.1 - 0.0037 17.4 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain RAP PF08373.10 EAN31262.1 - 0.022 14.8 0.6 0.11 12.6 0.1 2.4 2 0 0 2 2 2 0 RAP domain Telomerase_RBD PF12009.8 EAN31264.1 - 4.3e-25 88.4 3.4 4.4e-25 88.3 0.4 2.8 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EAN31264.1 - 9.7e-13 48.1 0.3 3.4e-08 33.3 0.0 2.8 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) FAINT PF04385.15 EAN31265.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Macro PF01661.21 EAN31266.1 - 0.0012 18.9 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Macro domain DUF3343 PF11823.8 EAN31266.1 - 0.0016 17.9 0.0 0.017 14.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3343) Ribosomal_L19 PF01245.20 EAN31266.1 - 1.3 8.9 4.2 3.6 7.5 2.9 2.5 3 1 0 3 3 3 0 Ribosomal protein L19 FYVE PF01363.21 EAN31268.1 - 9.2e-06 25.7 0.4 1.3e-05 25.2 0.4 1.2 1 0 0 1 1 1 1 FYVE zinc finger DUF148 PF02520.17 EAN31268.1 - 0.011 15.8 0.3 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 C1_1 PF00130.22 EAN31268.1 - 0.014 15.3 5.7 0.025 14.4 5.7 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IBR PF01485.21 EAN31268.1 - 0.037 14.2 3.3 0.072 13.3 3.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-B_box PF00643.24 EAN31268.1 - 0.14 12.4 6.3 0.22 11.7 6.3 1.3 1 0 0 1 1 1 0 B-box zinc finger C1_2 PF03107.16 EAN31268.1 - 0.32 11.3 7.3 0.72 10.2 7.3 1.6 1 0 0 1 1 1 0 C1 domain zf-C2H2_6 PF13912.6 EAN31268.1 - 0.48 10.5 8.9 1.5 8.9 0.1 3.1 2 1 1 3 3 3 0 C2H2-type zinc finger zf-AN1 PF01428.16 EAN31268.1 - 6.8 6.9 11.2 50 4.2 11.2 2.0 1 1 1 2 2 2 0 AN1-like Zinc finger zf-met PF12874.7 EAN31268.1 - 7 7.2 10.2 1.8 9.1 5.6 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EAN31268.1 - 8.8 7.5 10.8 38 5.5 5.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger YhfH PF14149.6 EAN31269.1 - 0.021 14.8 0.3 0.096 12.7 0.3 2.2 1 0 0 1 1 1 0 YhfH-like protein DUF4839 PF16127.5 EAN31269.1 - 0.078 13.1 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4839) Sdh5 PF03937.16 EAN31270.1 - 0.0013 18.7 0.1 0.0022 17.9 0.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase AP2 PF00847.20 EAN31271.1 - 3.3e-37 126.5 23.1 2.6e-14 53.2 1.5 3.5 3 0 0 3 3 3 3 AP2 domain DUF1610 PF07754.11 EAN31272.1 - 7e-06 25.9 1.7 0.074 13.0 0.4 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1610) Nudix_N_2 PF14803.6 EAN31272.1 - 0.00084 19.2 0.7 0.13 12.2 0.0 2.3 2 0 0 2 2 2 1 Nudix N-terminal TF_Zn_Ribbon PF08271.12 EAN31272.1 - 0.0011 18.4 1.2 0.46 10.1 0.4 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.7 EAN31272.1 - 0.0012 18.8 1.2 0.19 11.7 0.1 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Auto_anti-p27 PF06677.12 EAN31272.1 - 0.0013 18.8 0.1 1.3 9.2 0.0 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rubredoxin PF00301.20 EAN31272.1 - 0.0056 16.7 4.6 0.81 9.8 4.6 2.3 1 1 0 1 1 1 1 Rubredoxin DUF35_N PF12172.8 EAN31272.1 - 0.019 14.9 6.4 0.062 13.2 0.4 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HypA PF01155.19 EAN31272.1 - 0.027 14.5 0.1 0.048 13.7 0.0 1.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Mss51 PF13824.6 EAN31272.1 - 0.028 14.5 3.2 1.6 8.8 0.3 2.6 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.6 EAN31272.1 - 0.032 13.6 4.7 0.42 10.1 0.7 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Headcase PF16002.5 EAN31272.1 - 0.04 13.4 0.6 0.078 12.4 0.6 1.4 1 0 0 1 1 1 0 Headcase protein zinc_ribbon_10 PF10058.9 EAN31272.1 - 0.041 13.6 0.9 8.9 6.1 0.1 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_2 PF13240.6 EAN31272.1 - 0.05 13.3 4.0 0.86 9.4 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EAN31272.1 - 0.055 13.6 7.5 0.071 13.2 4.3 2.4 2 2 0 2 2 2 0 Zinc ribbon domain CpXC PF14353.6 EAN31272.1 - 0.078 13.0 0.7 15 5.7 0.1 2.6 3 0 0 3 3 3 0 CpXC protein Zn_ribbon_SprT PF17283.2 EAN31272.1 - 0.1 12.5 3.3 2.2 8.2 0.3 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain TFIIS_C PF01096.18 EAN31272.1 - 0.1 12.4 2.0 10 6.0 0.2 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-H2C2_2 PF13465.6 EAN31272.1 - 0.11 13.0 1.8 18 6.0 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain GFA PF04828.14 EAN31272.1 - 0.17 12.2 4.7 0.35 11.2 0.1 2.6 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-IS66 PF13005.7 EAN31272.1 - 0.18 12.3 1.3 9.2 6.8 0.0 2.3 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 DZR PF12773.7 EAN31272.1 - 0.33 11.0 3.7 0.93 9.6 2.3 2.3 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_7 PF02591.15 EAN31272.1 - 1.1 9.5 3.9 2.4 8.4 0.1 2.9 3 0 0 3 3 3 0 C4-type zinc ribbon domain Rubredoxin_2 PF18073.1 EAN31272.1 - 9.5 6.1 10.0 6.1 6.7 1.0 3.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain Ribonuc_red_lgC PF02867.15 EAN31273.1 - 1.9e-186 620.7 0.0 2.7e-186 620.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EAN31273.1 - 5.2e-25 87.3 0.1 3.2e-24 84.7 0.0 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EAN31273.1 - 1e-10 42.0 0.0 2.2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain Hydrophob_seed PF14547.6 EAN31273.1 - 0.19 11.9 1.6 0.33 11.2 0.9 1.7 2 0 0 2 2 2 0 Hydrophobic seed protein Spo7 PF03907.13 EAN31275.1 - 0.09 12.2 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Spo7-like protein HIT PF01230.23 EAN31276.1 - 1.5e-21 76.9 0.0 2.2e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EAN31276.1 - 1.9e-05 25.1 0.1 3.5e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EAN31276.1 - 0.023 14.6 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 DEAD PF00270.29 EAN31277.1 - 2.4e-48 164.2 0.0 5.3e-48 163.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN31277.1 - 1.3e-27 96.3 0.0 4.3e-27 94.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN31277.1 - 0.0044 17.0 0.0 0.015 15.3 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RCC1 PF00415.18 EAN31279.1 - 8.8e-102 333.6 56.3 7.2e-12 45.7 0.1 15.9 15 3 0 15 15 15 13 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAN31279.1 - 2.5e-48 161.0 86.7 2.6e-08 33.5 0.4 13.8 14 1 0 14 14 14 10 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 EAN31279.1 - 0.032 13.9 0.4 4.2 7.0 0.0 3.5 4 0 0 4 4 4 0 TUP1-like enhancer of split PQQ_3 PF13570.6 EAN31279.1 - 4.1 8.0 8.9 17 6.1 0.3 3.9 3 0 0 3 3 3 0 PQQ-like domain RasGAP_C PF03836.15 EAN31280.1 - 0.092 12.9 1.1 0.2 11.8 1.1 1.5 1 0 0 1 1 1 0 RasGAP C-terminus TPT PF03151.16 EAN31281.1 - 3.7e-82 275.9 22.3 4.2e-82 275.7 22.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EAN31281.1 - 9.5e-06 25.8 30.4 0.0009 19.4 12.1 2.7 2 2 0 2 2 2 2 EamA-like transporter family DUF2183 PF09949.9 EAN31282.1 - 4.6e-05 23.7 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Ank_2 PF12796.7 EAN31283.1 - 1e-21 77.3 8.6 3e-14 53.4 1.4 3.6 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAN31283.1 - 7.1e-14 52.0 5.0 1.4e-07 31.9 0.4 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAN31283.1 - 3.5e-13 49.3 8.6 0.00021 21.6 0.4 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAN31283.1 - 3e-11 42.5 2.2 0.0007 19.9 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAN31283.1 - 3e-05 24.2 6.6 3.9e-05 23.8 1.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) SET PF00856.28 EAN31283.1 - 0.14 12.5 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 SET domain Pyr_redox_2 PF07992.14 EAN31284.1 - 5.5e-39 134.2 0.0 7.1e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAN31284.1 - 5e-08 33.4 0.0 4e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UQ_con PF00179.26 EAN31285.1 - 4.6e-42 143.0 0.0 5.2e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAN31285.1 - 0.016 14.9 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B MFS_1 PF07690.16 EAN31286.1 - 8.8e-17 61.1 19.9 1.6e-16 60.2 19.9 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EAN31286.1 - 0.22 10.0 26.6 0.0099 14.5 3.6 3.5 2 2 1 3 3 3 0 MFS/sugar transport protein OppC_N PF12911.7 EAN31286.1 - 0.65 10.0 4.5 3 7.9 0.7 3.4 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Sld5 PF05916.11 EAN31287.1 - 3.7e-08 33.8 0.0 6.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein MFS_1 PF07690.16 EAN31288.1 - 1.7e-16 60.1 11.1 2.8e-16 59.4 11.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Kelch_6 PF13964.6 EAN31288.1 - 0.12 12.7 0.8 0.68 10.3 0.0 2.7 3 0 0 3 3 3 0 Kelch motif MFS_1 PF07690.16 EAN31290.1 - 6.4e-10 38.5 19.0 6.4e-10 38.5 19.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TMEM138 PF14935.6 EAN31290.1 - 1.8 9.2 6.0 0.67 10.6 1.2 2.8 2 1 0 2 2 2 0 Transmembrane protein 138 Elf1 PF05129.13 EAN31292.1 - 3.1e-22 78.4 0.5 5.5e-22 77.6 0.5 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 EAN31292.1 - 0.092 12.9 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain PBS_linker_poly PF00427.21 EAN31293.1 - 0.076 13.1 0.4 31 4.6 0.0 3.3 3 0 0 3 3 3 0 Phycobilisome Linker polypeptide DNA_ligase_A_M PF01068.21 EAN31294.1 - 2.8e-55 187.1 0.1 7.2e-55 185.8 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EAN31294.1 - 4.5e-32 111.8 0.1 8.1e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EAN31294.1 - 3e-25 88.7 0.0 7.6e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EAN31294.1 - 2.1e-06 28.1 0.1 3.5e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 EAN31294.1 - 0.0042 16.9 0.4 0.11 12.2 0.4 2.7 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain ubiquitin PF00240.23 EAN31295.1 - 3.2 7.6 5.6 46 3.9 0.5 3.3 2 1 2 4 4 4 0 Ubiquitin family RLL PF10036.9 EAN31296.1 - 5.4e-17 62.5 5.7 7.9e-17 62.0 5.7 1.2 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein zf-C3HC4_2 PF13923.6 EAN31297.1 - 1.6e-06 27.8 10.2 2.9e-06 27.0 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAN31297.1 - 2.6e-05 24.0 9.5 5.4e-05 23.0 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN31297.1 - 4.8e-05 23.3 7.6 0.0001 22.2 7.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EAN31297.1 - 0.00093 19.5 8.9 0.0017 18.6 8.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EAN31297.1 - 0.0021 17.9 4.8 0.0037 17.1 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAN31297.1 - 0.019 15.1 9.1 0.035 14.3 9.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EAN31297.1 - 0.033 14.1 9.9 0.08 12.9 9.9 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 EAN31297.1 - 0.045 13.6 5.2 0.15 11.9 5.2 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Trm112p PF03966.16 EAN31297.1 - 0.18 12.4 2.4 0.58 10.8 2.4 1.9 1 0 0 1 1 1 0 Trm112p-like protein Prok-RING_4 PF14447.6 EAN31297.1 - 0.9 9.4 10.1 15 5.5 10.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SET PF00856.28 EAN31298.1 - 0.00024 21.6 6.8 0.00072 20.0 6.0 2.5 2 1 0 2 2 2 1 SET domain DUF5334 PF17268.2 EAN31300.1 - 0.85 10.0 3.2 2.6 8.4 3.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5334) DUF4372 PF14294.6 EAN31301.1 - 0.063 13.4 1.5 1.5 9.0 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4372) TFIIE_beta PF02186.15 EAN31302.1 - 0.0019 18.4 0.6 0.007 16.6 0.6 2.0 1 0 0 1 1 1 1 TFIIE beta subunit core domain HTH_12 PF08461.10 EAN31302.1 - 0.083 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain G6PD_C PF02781.16 EAN31303.1 - 4.6e-63 213.1 0.0 7.3e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EAN31303.1 - 3.6e-38 131.9 0.0 7.5e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glucosamine_iso PF01182.20 EAN31303.1 - 1.9e-37 129.4 0.0 3.1e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF410 PF04190.13 EAN31304.1 - 4.7e-49 167.5 0.8 6.3e-49 167.1 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) SNAP PF14938.6 EAN31304.1 - 5.3e-05 22.8 1.0 0.00034 20.1 0.1 2.1 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP Cdc6_C PF09079.11 EAN31304.1 - 0.092 12.7 0.3 0.25 11.3 0.1 1.9 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain TPR_2 PF07719.17 EAN31304.1 - 0.83 9.9 5.2 53 4.3 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Beta-Casp PF10996.8 EAN31305.1 - 5.5e-27 94.2 0.0 1.1e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 EAN31305.1 - 1e-18 67.0 0.0 2e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 EAN31305.1 - 5.5e-18 65.1 0.0 1.8e-17 63.4 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain CPSF73-100_C PF11718.8 EAN31305.1 - 2e-16 60.2 5.6 3.5e-16 59.4 5.6 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B PF00753.27 EAN31305.1 - 3.7e-15 56.4 0.0 4.1e-14 53.1 0.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Beta_lactamase3 PF17030.5 EAN31305.1 - 6.3e-06 25.6 0.0 2.7e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 Putative beta-lactamase-like family Lactamase_B_2 PF12706.7 EAN31305.1 - 7.4e-06 25.6 0.0 0.00042 19.9 0.0 3.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EAN31305.1 - 0.016 15.1 0.3 0.093 12.6 0.1 2.2 2 1 0 2 2 2 0 Beta-lactamase superfamily domain GpcrRhopsn4 PF10192.9 EAN31306.1 - 0.0026 17.2 18.7 0.0056 16.1 18.7 1.6 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Sigma_reg_N PF13800.6 EAN31307.1 - 0.072 13.4 0.8 5.8 7.3 0.0 3.4 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF3742 PF12553.8 EAN31307.1 - 0.57 10.3 3.2 10 6.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) Tetraspanin PF00335.20 EAN31307.1 - 1.3 8.6 10.2 0.93 9.1 0.1 3.4 3 0 0 3 3 3 0 Tetraspanin family Sigma_reg_N PF13800.6 EAN31308.1 - 0.059 13.7 3.7 1.6 9.1 0.1 3.4 3 0 0 3 3 3 0 Sigma factor regulator N-terminal RFC1 PF08519.12 EAN31310.1 - 3.5e-31 108.5 1.1 1.1e-30 106.8 1.1 2.0 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 EAN31310.1 - 7e-10 39.4 0.0 1.7e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 EAN31310.1 - 1.1e-07 32.1 3.8 2.3e-07 31.1 0.0 3.4 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain AAA_22 PF13401.6 EAN31310.1 - 2.9e-06 27.6 0.0 1.3e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EAN31310.1 - 2.9e-06 27.3 3.0 3.3e-06 27.2 0.1 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 EAN31310.1 - 0.00014 21.6 0.0 0.00052 19.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EAN31310.1 - 0.0028 17.7 0.5 0.02 14.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EAN31310.1 - 0.0087 16.4 4.4 1.1 9.6 0.2 3.5 2 1 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 EAN31310.1 - 0.0087 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 EAN31310.1 - 0.034 14.1 0.3 0.57 10.1 0.3 2.6 1 1 0 1 1 1 0 NTPase AAA_assoc_2 PF16193.5 EAN31310.1 - 0.036 14.4 0.0 0.18 12.1 0.0 2.3 1 0 0 1 1 1 0 AAA C-terminal domain AAA_5 PF07728.14 EAN31310.1 - 0.045 13.7 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EAN31310.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Erf4 PF10256.9 EAN31310.1 - 3.9 7.6 6.9 11 6.1 0.1 3.8 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family Ribosomal_S30 PF04758.14 EAN31311.1 - 8.8e-26 89.9 10.9 1e-25 89.7 10.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Sec1 PF00995.23 EAN31312.1 - 1.8e-105 354.4 24.9 2.1e-105 354.2 24.9 1.0 1 0 0 1 1 1 1 Sec1 family Uteroglobin PF01099.17 EAN31312.1 - 0.0087 16.4 0.3 0.03 14.6 0.3 1.9 1 0 0 1 1 1 1 Uteroglobin family Terpene_synth_C PF03936.16 EAN31313.1 - 0.00055 19.4 0.0 0.00066 19.1 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ABG_transport PF03806.13 EAN31313.1 - 0.2 9.9 0.0 0.23 9.6 0.0 1.0 1 0 0 1 1 1 0 AbgT putative transporter family ATP-synt_ab PF00006.25 EAN31314.1 - 6.8e-71 238.3 0.0 9.2e-71 237.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EAN31314.1 - 3.3e-43 147.0 0.9 4.9e-43 146.4 0.9 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EAN31314.1 - 2.5e-15 56.8 2.0 7e-15 55.3 2.0 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 EAN31314.1 - 0.0022 18.1 0.7 0.0053 16.9 0.7 1.6 1 0 0 1 1 1 1 HAS barrel domain CSD PF00313.22 EAN31315.1 - 5.8e-24 83.7 0.1 7.6e-24 83.4 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EAN31315.1 - 0.0018 17.9 0.1 0.0039 16.8 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.23 EAN31315.1 - 0.073 13.4 0.1 0.099 13.0 0.1 1.2 1 0 0 1 1 1 0 S1 RNA binding domain CECR6_TMEM121 PF14997.6 EAN31316.1 - 1.2e-12 48.1 11.2 1.2e-12 48.1 11.2 3.1 2 1 0 2 2 2 1 CECR6/TMEM121 family SMK-1 PF04802.15 EAN31318.1 - 9.8e-18 64.7 7.0 9.8e-18 64.7 7.0 2.2 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 RTP1_C2 PF10304.9 EAN31318.1 - 0.12 12.1 2.4 0.13 12.0 0.1 2.4 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 DNA_pol_E_B PF04042.16 EAN31319.1 - 0.0034 16.8 0.0 0.0041 16.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNTTIP1_dimer PF18192.1 EAN31319.1 - 0.064 13.6 0.4 0.14 12.5 0.4 1.6 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain BING4CT PF08149.11 EAN31321.1 - 4.2e-33 113.0 0.0 3.8e-31 106.7 0.0 3.1 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 EAN31321.1 - 0.00011 22.9 2.7 0.13 13.2 0.2 4.7 4 1 1 5 5 5 1 WD domain, G-beta repeat WD40_like PF17005.5 EAN31321.1 - 0.0011 18.3 0.4 0.041 13.2 0.1 2.4 2 0 0 2 2 2 1 WD40-like domain Cwf_Cwc_15 PF04889.12 EAN31322.1 - 1.1e-26 94.1 13.3 5e-13 49.3 0.7 2.0 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 EAN31322.1 - 0.016 15.0 6.6 0.022 14.6 6.6 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing MMR_HSR1 PF01926.23 EAN31323.1 - 5.7e-20 71.5 0.0 2.2e-19 69.6 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase YchF-GTPase_C PF06071.13 EAN31323.1 - 1.5e-10 41.1 0.0 4.9e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF933) FeoB_N PF02421.18 EAN31323.1 - 3.4e-05 23.4 0.0 8.1e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 EAN31323.1 - 0.0027 18.1 0.1 0.023 15.1 0.0 2.3 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) LAGLIDADG_1 PF00961.19 EAN31323.1 - 0.15 13.0 2.1 0.44 11.5 2.1 1.7 1 0 0 1 1 1 0 LAGLIDADG endonuclease ABC_tran PF00005.27 EAN31323.1 - 0.19 12.2 1.7 3.5 8.2 0.0 2.7 2 1 0 2 2 2 0 ABC transporter NuA4 PF09340.10 EAN31324.1 - 8.2e-06 25.6 0.2 3.1e-05 23.7 0.2 2.0 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Axin_b-cat_bind PF08833.10 EAN31324.1 - 4.5 7.5 10.9 1.6 8.9 1.1 3.9 2 2 2 4 4 4 0 Axin beta-catenin binding domain NADHdh_A3 PF14987.6 EAN31325.1 - 0.27 11.6 4.7 0.49 10.7 0.3 3.2 2 1 1 3 3 3 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 RE_HaeIII PF09556.10 EAN31326.1 - 0.067 12.3 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease FAINT PF04385.15 EAN31327.1 - 0.0067 16.5 1.6 0.027 14.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function, DUF529 DUF4024 PF13216.6 EAN31328.1 - 0.019 14.9 1.2 0.065 13.2 1.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) SSTK-IP PF15836.5 EAN31328.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein TGT PF01702.18 EAN31331.1 - 1.4e-26 93.5 0.0 2.8e-26 92.5 0.0 1.5 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase TPR_1 PF00515.28 EAN31332.1 - 2.8e-63 207.3 42.1 1.2e-08 34.4 0.8 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 EAN31332.1 - 1.4e-51 168.5 30.5 2.8e-06 27.0 0.5 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.6 EAN31332.1 - 5e-32 109.3 18.8 9.4e-09 34.8 0.6 8.5 6 2 2 8 8 8 6 TPR repeat TPR_8 PF13181.6 EAN31332.1 - 6.4e-30 100.8 30.1 7.2e-05 22.7 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 EAN31332.1 - 3.2e-23 81.8 9.6 9.5e-09 35.4 0.1 7.1 5 3 2 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 EAN31332.1 - 2.3e-21 76.0 11.5 5.7e-07 30.0 0.1 7.4 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 EAN31332.1 - 1.7e-20 71.8 25.4 0.0003 21.0 0.6 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat STI1 PF17830.1 EAN31332.1 - 5.9e-20 71.0 5.5 5.2e-15 55.1 0.5 3.2 2 0 0 2 2 2 2 STI1 domain TPR_14 PF13428.6 EAN31332.1 - 7.2e-20 70.0 0.1 0.76 10.8 0.0 8.6 6 2 2 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 EAN31332.1 - 2.1e-17 63.5 0.9 6.6e-05 23.5 0.1 5.9 3 3 5 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 EAN31332.1 - 4.8e-15 54.4 6.6 0.0033 17.3 0.1 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 EAN31332.1 - 5.1e-11 42.6 0.0 0.28 11.4 0.0 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EAN31332.1 - 2.9e-09 36.9 12.0 0.96 10.2 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAN31332.1 - 1.1e-06 28.3 9.3 4 7.5 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat NARP1 PF12569.8 EAN31332.1 - 2.4e-06 26.8 10.6 0.07 12.0 0.1 4.0 2 2 2 4 4 4 3 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 EAN31332.1 - 7.6e-06 25.9 25.3 0.44 10.7 0.1 8.3 9 1 1 10 10 10 4 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 EAN31332.1 - 9.3e-05 22.5 6.5 0.11 12.6 0.2 4.3 3 2 0 3 3 3 1 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 EAN31332.1 - 0.00011 22.3 17.8 0.0023 18.1 3.7 5.4 2 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 EAN31332.1 - 0.00038 19.9 5.2 29 4.2 0.0 6.4 6 0 0 6 6 6 0 SHNi-TPR TPR_15 PF13429.6 EAN31332.1 - 0.0005 19.4 2.6 2 7.6 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 EAN31332.1 - 0.00062 20.1 0.3 5.6 7.4 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Paf67 PF10255.9 EAN31332.1 - 0.0039 16.2 0.4 0.013 14.6 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 RPN7 PF10602.9 EAN31332.1 - 0.024 14.3 12.1 0.13 12.0 1.9 3.7 1 1 2 3 3 3 0 26S proteasome subunit RPN7 Alkyl_sulf_dimr PF14863.6 EAN31332.1 - 0.036 14.5 0.1 0.37 11.3 0.0 2.7 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation DUF1102 PF06510.11 EAN31332.1 - 0.05 13.8 0.0 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1102) PPR PF01535.20 EAN31332.1 - 0.067 13.5 7.8 17 5.9 0.1 5.9 5 1 1 6 6 6 0 PPR repeat TOM20_plant PF06552.12 EAN31332.1 - 0.083 12.6 3.4 9.2 6.0 0.0 4.3 4 0 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 SPO22 PF08631.10 EAN31332.1 - 0.2 11.1 3.7 9 5.7 0.2 3.9 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like XPC-binding PF09280.11 EAN31332.1 - 1 9.2 7.6 47 3.8 0.1 3.7 2 1 1 3 3 3 0 XPC-binding domain ChAPs PF09295.10 EAN31332.1 - 1.6 7.7 6.8 4.3 6.2 0.2 3.3 4 1 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.14 EAN31332.1 - 2.8 7.3 9.2 0.57 9.5 0.3 3.5 2 1 3 5 5 5 0 Coatomer epsilon subunit MIT PF04212.18 EAN31332.1 - 5.2 7.2 15.8 2.8 8.1 0.2 6.7 8 1 1 9 9 6 0 MIT (microtubule interacting and transport) domain Symplekin_C PF12295.8 EAN31335.1 - 0.081 13.0 0.3 0.35 11.0 0.1 2.2 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal DUF2681 PF10883.8 EAN31335.1 - 0.33 11.4 2.7 1.6 9.2 2.7 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) AAA_5 PF07728.14 EAN31336.1 - 3e-76 254.0 0.0 2e-19 69.9 0.0 5.6 5 0 0 5 5 5 5 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EAN31336.1 - 4.6e-20 71.8 0.0 5.7e-05 23.0 0.0 5.4 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EAN31336.1 - 3.7e-17 62.4 6.2 4.9e-05 22.9 0.1 6.4 6 0 0 6 6 6 3 P-loop containing dynein motor region AAA_16 PF13191.6 EAN31336.1 - 7.5e-15 55.7 0.0 0.0029 18.0 0.0 4.6 4 0 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 EAN31336.1 - 8.9e-15 55.3 0.1 0.0069 16.8 0.0 5.0 4 0 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 EAN31336.1 - 5.4e-14 51.9 4.6 0.0015 17.6 0.0 6.1 6 0 0 6 6 6 3 Hydrolytic ATP binding site of dynein motor region AAA_14 PF13173.6 EAN31336.1 - 1.4e-13 51.0 2.7 0.026 14.6 0.0 5.3 4 0 0 4 4 4 3 AAA domain TsaE PF02367.17 EAN31336.1 - 1.4e-11 44.4 0.1 0.087 12.8 0.0 4.5 4 0 0 4 4 4 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EAN31336.1 - 2.9e-11 43.2 0.0 8.2e-05 22.1 0.0 4.9 5 0 0 5 5 5 1 Magnesium chelatase, subunit ChlI AAA_lid_5 PF17865.1 EAN31336.1 - 8.1e-11 41.9 0.9 5.9e-10 39.2 0.1 3.0 3 0 0 3 3 1 1 Midasin AAA lid domain Sigma54_activat PF00158.26 EAN31336.1 - 5.9e-10 39.1 0.0 0.1 12.3 0.0 4.6 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_22 PF13401.6 EAN31336.1 - 2e-09 37.9 2.7 0.14 12.4 0.0 4.7 5 0 0 5 5 3 3 AAA domain Sigma54_activ_2 PF14532.6 EAN31336.1 - 5.7e-09 36.2 0.0 0.027 14.6 0.0 3.7 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_lid_7 PF17867.1 EAN31336.1 - 8.4e-09 35.6 0.1 2.8e-07 30.7 0.0 3.4 3 1 1 4 4 4 1 Midasin AAA lid domain MCM PF00493.23 EAN31336.1 - 9.6e-09 34.7 0.0 0.89 8.6 0.0 4.7 4 0 0 4 4 4 2 MCM P-loop domain Dynein_heavy PF03028.15 EAN31336.1 - 6.5e-08 32.7 1.0 0.2 11.8 0.0 5.7 5 1 0 5 5 5 2 Dynein heavy chain region D6 P-loop domain ABC_tran PF00005.27 EAN31336.1 - 9.9e-08 32.6 1.6 0.0061 17.1 0.0 4.1 4 0 0 4 4 3 2 ABC transporter NACHT PF05729.12 EAN31336.1 - 2.9e-07 30.6 7.4 0.14 12.1 0.1 4.6 5 0 0 5 5 4 3 NACHT domain T2SSE PF00437.20 EAN31336.1 - 3.3e-07 29.6 0.1 0.1 11.7 0.0 4.1 5 0 0 5 5 3 2 Type II/IV secretion system protein DUF815 PF05673.13 EAN31336.1 - 3.5e-07 29.6 0.0 0.66 9.1 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EAN31336.1 - 5.9e-07 29.4 0.0 1.4 8.6 0.0 4.7 5 0 0 5 5 4 2 IstB-like ATP binding protein TniB PF05621.11 EAN31336.1 - 1.8e-06 27.5 0.4 0.15 11.4 0.0 4.2 4 0 0 4 4 4 2 Bacterial TniB protein RsgA_GTPase PF03193.16 EAN31336.1 - 4.2e-06 26.8 0.4 0.39 10.6 0.0 3.8 4 0 0 4 4 3 2 RsgA GTPase Roc PF08477.13 EAN31336.1 - 6.7e-06 26.3 2.2 0.49 10.6 0.1 4.0 4 0 0 4 4 3 2 Ras of Complex, Roc, domain of DAPkinase RuvB_N PF05496.12 EAN31336.1 - 7.8e-06 25.7 0.1 0.13 12.0 0.0 4.2 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 EAN31336.1 - 8.3e-06 25.2 0.0 2.4 7.4 0.0 4.4 4 0 0 4 4 4 1 Zeta toxin RNA_helicase PF00910.22 EAN31336.1 - 8.8e-06 26.1 3.1 4 7.9 0.0 5.3 5 0 0 5 5 4 0 RNA helicase SRP54 PF00448.22 EAN31336.1 - 1.6e-05 24.7 4.8 1.4 8.5 0.1 3.7 4 0 0 4 4 3 3 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 EAN31336.1 - 1.7e-05 24.6 0.9 0.37 10.5 0.0 3.8 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 EAN31336.1 - 2e-05 24.6 1.7 0.72 9.7 0.0 5.6 6 0 0 6 6 5 1 Rad17 P-loop domain TIP49 PF06068.13 EAN31336.1 - 2.1e-05 23.9 0.1 0.5 9.5 0.0 3.8 4 0 0 4 4 4 2 TIP49 P-loop domain AAA_33 PF13671.6 EAN31336.1 - 5.6e-05 23.3 0.0 8.4 6.5 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 EAN31336.1 - 7.4e-05 22.4 0.0 1.3 8.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.6 EAN31336.1 - 7.5e-05 23.1 3.7 1.9 8.8 0.1 4.5 4 1 0 4 4 3 1 AAA domain AAA_24 PF13479.6 EAN31336.1 - 0.00012 21.9 2.2 1.4 8.6 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 EAN31336.1 - 0.00013 21.7 1.2 2.1 8.1 0.1 3.9 4 0 0 4 4 3 1 P-loop containing region of AAA domain AAA_8 PF12780.7 EAN31336.1 - 0.00015 21.2 4.3 0.5 9.6 0.1 3.9 3 1 0 3 3 3 2 P-loop containing dynein motor region D4 ResIII PF04851.15 EAN31336.1 - 0.00017 21.6 5.2 1.4 8.9 0.0 4.9 4 1 0 5 5 4 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EAN31336.1 - 0.00018 22.1 5.6 2.7 8.5 0.0 5.7 5 0 0 5 5 4 1 AAA domain DEAD PF00270.29 EAN31336.1 - 0.0002 21.2 0.7 0.36 10.6 0.0 3.7 4 1 0 5 5 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EAN31336.1 - 0.00055 19.7 0.0 3 7.5 0.0 3.7 5 0 0 5 5 3 1 AAA domain ATPase PF06745.13 EAN31336.1 - 0.0007 19.0 1.9 0.18 11.1 0.0 3.5 5 0 0 5 5 3 1 KaiC NB-ARC PF00931.22 EAN31336.1 - 0.0096 15.1 0.1 6.8 5.8 0.0 3.6 4 0 0 4 4 3 0 NB-ARC domain SRPRB PF09439.10 EAN31336.1 - 0.016 14.7 5.8 17 4.8 0.0 4.4 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 EAN31336.1 - 0.02 15.4 17.2 1.7 9.1 0.0 4.8 4 1 0 4 4 3 0 AAA domain ATP-synt_ab PF00006.25 EAN31336.1 - 0.027 14.1 0.0 1.1 8.9 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 EAN31336.1 - 0.038 13.9 10.0 2.6 7.9 0.3 4.1 4 0 0 4 4 3 0 NTPase Ras PF00071.22 EAN31336.1 - 0.048 13.3 0.9 6.6 6.3 0.1 2.8 2 0 0 2 2 2 0 Ras family FtsK_SpoIIIE PF01580.18 EAN31336.1 - 0.059 12.7 0.0 2.8 7.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EAN31336.1 - 0.069 13.2 1.5 33 4.6 0.1 3.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF87 PF01935.17 EAN31336.1 - 0.09 12.9 8.3 0.34 11.0 0.1 4.4 4 0 0 4 4 3 0 Helicase HerA, central domain PhoH PF02562.16 EAN31336.1 - 0.14 11.5 0.2 5.9 6.3 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein cobW PF02492.19 EAN31336.1 - 0.31 10.6 5.8 6.6 6.3 0.0 4.0 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.17 EAN31336.1 - 0.37 10.4 1.9 93 2.6 0.0 4.3 5 0 0 5 5 4 0 Thymidylate kinase TrwB_AAD_bind PF10412.9 EAN31336.1 - 0.42 9.5 1.3 14 4.4 0.1 2.6 3 0 0 3 3 2 0 Type IV secretion-system coupling protein DNA-binding domain MAM33 PF02330.16 EAN31337.1 - 1.4e-31 110.1 0.4 6.1e-31 108.0 0.4 1.8 1 1 0 1 1 1 1 Mitochondrial glycoprotein Peptidase_M24 PF00557.24 EAN31338.1 - 1.1e-41 142.8 0.0 1.4e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 COX15-CtaA PF02628.15 EAN31339.1 - 8.5e-81 271.5 0.7 1e-80 271.3 0.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein RNase_H2-Ydr279 PF09468.10 EAN31340.1 - 2.3e-07 31.1 1.0 4.2e-07 30.3 1.0 1.5 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Clathrin_lg_ch PF01086.17 EAN31341.1 - 0.00052 20.1 7.1 0.0006 19.9 7.1 1.2 1 0 0 1 1 1 1 Clathrin light chain Glyco_transf_92 PF01697.27 EAN31341.1 - 0.021 14.5 2.4 0.026 14.2 2.4 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 HNH_4 PF13395.6 EAN31341.1 - 0.025 14.5 1.4 0.077 12.9 1.4 1.9 1 1 0 1 1 1 0 HNH endonuclease HALZ PF02183.18 EAN31342.1 - 0.00069 19.8 3.3 0.00069 19.8 3.3 11.4 9 3 3 12 12 12 6 Homeobox associated leucine zipper BOP1NT PF08145.12 EAN31343.1 - 1.3e-84 284.2 7.1 1.9e-84 283.7 7.1 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain NRBF2 PF08961.10 EAN31345.1 - 0.0005 19.7 2.2 0.0006 19.5 2.2 1.2 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator AAA_18 PF13238.6 EAN31345.1 - 0.038 14.5 0.8 0.048 14.2 0.8 1.3 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.8 EAN31345.1 - 1.1 9.3 7.5 0.42 10.6 1.4 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding cobW PF02492.19 EAN31346.1 - 6.2e-41 139.9 0.1 9e-41 139.4 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EAN31346.1 - 0.0015 18.7 0.0 0.0085 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAN31346.1 - 0.0021 18.5 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 EAN31346.1 - 0.0021 17.1 0.1 0.82 8.6 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EAN31346.1 - 0.0044 16.9 0.7 0.0081 16.1 0.3 1.6 2 0 0 2 2 2 1 NTPase TsaE PF02367.17 EAN31346.1 - 0.0059 16.6 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EAN31346.1 - 0.0074 16.6 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain CobW_C PF07683.14 EAN31346.1 - 0.0096 15.8 0.0 0.022 14.7 0.0 1.7 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 EAN31346.1 - 0.021 14.7 0.2 0.054 13.4 0.2 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 EAN31346.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 EAN31346.1 - 0.033 14.6 0.1 0.066 13.6 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EAN31346.1 - 0.034 14.7 0.3 0.26 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAN31346.1 - 0.051 14.1 1.8 0.12 12.9 1.8 1.9 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EAN31346.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 EAN31346.1 - 0.06 13.2 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 EAN31346.1 - 0.089 12.8 0.9 0.26 11.3 0.1 2.2 3 0 0 3 3 2 0 AAA domain CHASE5 PF17149.4 EAN31346.1 - 0.097 12.6 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Periplasmic sensor domain found in signal transduction proteins AAA_7 PF12775.7 EAN31346.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EAN31346.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAN31346.1 - 0.2 12.0 0.2 0.47 10.8 0.1 1.6 2 0 0 2 2 2 0 AAA domain Porin_3 PF01459.22 EAN31347.1 - 7.2e-07 28.9 0.4 1.6e-06 27.8 0.4 1.6 1 1 0 1 1 1 1 Eukaryotic porin Ribosomal_L35Ae PF01247.18 EAN31348.1 - 8.5e-45 150.9 1.7 1e-44 150.6 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EAN31348.1 - 0.0017 18.6 0.4 0.47 10.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Ribosomal_L28e PF01778.17 EAN31349.1 - 2.4e-24 86.3 3.4 2.8e-24 86.1 3.4 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family Glycos_transf_1 PF00534.20 EAN31349.1 - 0.11 12.0 0.0 7.1 6.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 Ish1 PF10281.9 EAN31351.1 - 0.00025 21.3 0.8 0.012 15.9 0.1 2.3 2 0 0 2 2 2 2 Putative stress-responsive nuclear envelope protein Abhydrolase_4 PF08386.10 EAN31352.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DNA_III_psi PF03603.13 EAN31352.1 - 0.3 11.3 2.4 10 6.4 0.2 2.5 2 0 0 2 2 2 0 DNA polymerase III psi subunit EF-hand_7 PF13499.6 EAN31354.1 - 5.1e-24 84.5 2.2 7.1e-15 55.2 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAN31354.1 - 4.8e-23 78.9 4.3 7.7e-07 28.2 0.3 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EAN31354.1 - 3.8e-21 73.2 4.9 2.7e-07 30.0 0.0 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EAN31354.1 - 1.5e-16 59.9 8.0 1.7e-11 43.8 0.4 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EAN31354.1 - 1.4e-08 35.0 0.3 4.8e-05 23.6 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EAN31354.1 - 3.2e-07 29.5 6.0 0.00021 20.6 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_14 PF17959.1 EAN31354.1 - 2.8e-06 27.6 0.3 0.072 13.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EAN31354.1 - 0.004 17.1 1.6 0.058 13.4 0.5 2.7 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 EAN31354.1 - 0.013 16.4 0.2 0.24 12.3 0.1 2.2 1 1 1 2 2 2 0 EF-hand domain IF2_N PF04760.15 EAN31354.1 - 0.34 10.8 1.3 37 4.3 0.0 3.4 4 0 0 4 4 4 0 Translation initiation factor IF-2, N-terminal region Img2 PF05046.14 EAN31356.1 - 5.1e-11 42.7 0.5 9.4e-11 41.9 0.3 1.5 1 1 1 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) T_cell_tran_alt PF15128.6 EAN31356.1 - 0.0032 17.2 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 T-cell leukemia translocation-altered FeThRed_A PF02941.15 EAN31356.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase variable alpha chain Hist_deacetyl PF00850.19 EAN31357.1 - 4.3e-74 249.8 0.0 6.2e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Ank_4 PF13637.6 EAN31358.1 - 1.8e-07 31.6 0.2 0.025 15.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAN31358.1 - 0.0015 19.1 0.0 1.6 9.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAN31358.1 - 0.049 14.0 0.0 0.31 11.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAN31358.1 - 0.19 12.4 0.4 13 6.7 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat FAINT PF04385.15 EAN31360.1 - 0.0002 21.4 16.2 0.009 16.1 2.8 2.8 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31361.1 - 1.7e-05 24.7 11.5 0.00011 22.2 1.4 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31362.1 - 0.0035 17.4 15.1 0.01 15.9 3.5 3.1 3 0 0 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31364.1 - 3.9e-15 55.7 18.0 4.2e-10 39.5 6.9 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN31365.1 - 5.1e-11 42.3 4.7 6.8e-08 32.4 1.6 3.2 2 0 0 2 2 2 2 Tash protein PEST motif FAINT PF04385.15 EAN31366.1 - 3.3e-07 30.3 9.2 1.4e-06 28.3 3.4 2.7 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31367.1 - 4e-08 33.2 9.9 1.5e-07 31.4 2.0 2.7 2 1 0 2 2 2 2 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN31367.1 - 4.9e-06 26.5 1.6 4.9e-06 26.5 1.6 2.4 2 0 0 2 2 2 1 Tash protein PEST motif DUF2201_N PF13203.6 EAN31367.1 - 0.13 11.8 1.7 0.22 11.1 1.7 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Merozoite_SPAM PF07133.11 EAN31367.1 - 1.1 9.2 11.8 2.1 8.3 11.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) FAINT PF04385.15 EAN31368.1 - 2.2e-05 24.4 1.2 2.2e-05 24.4 1.2 3.3 4 1 0 4 4 4 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31369.1 - 3.6e-07 30.1 15.4 1.5e-06 28.1 0.8 3.5 4 0 0 4 4 4 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31370.1 - 0.67 10.0 16.5 0.19 11.8 0.8 3.9 2 1 2 4 4 4 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31371.1 - 1.1e-05 25.4 7.8 0.051 13.6 1.9 3.4 2 1 1 3 3 3 2 Domain of unknown function, DUF529 FAM183 PF14886.6 EAN31371.1 - 0.34 11.7 2.6 1.4 9.6 2.6 2.0 1 1 0 1 1 1 0 FAM183A and FAM183B related FAINT PF04385.15 EAN31372.1 - 2.4e-27 94.8 16.0 1.1e-07 31.8 0.4 5.8 5 0 0 5 5 5 5 Domain of unknown function, DUF529 EMA PF02488.15 EAN31372.1 - 0.0037 17.0 2.4 0.011 15.4 2.2 2.0 1 1 0 1 1 1 1 Merozoite Antigen SspH PF08141.12 EAN31372.1 - 0.14 12.3 0.1 27 5.0 0.1 3.3 3 0 0 3 3 3 0 Small acid-soluble spore protein H family SCVP PF17619.2 EAN31372.1 - 0.36 11.7 5.0 3.6 8.5 0.1 3.7 5 0 0 5 5 5 0 Secreted clade V proteins ABC_tran PF00005.27 EAN31373.1 - 5.3e-33 114.4 0.0 8.7e-18 65.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EAN31373.1 - 1.8e-06 28.0 0.9 0.018 14.9 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EAN31373.1 - 4.7e-05 22.7 0.1 0.063 12.6 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 EAN31373.1 - 6.1e-05 23.5 0.1 0.075 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 EAN31373.1 - 0.00012 21.1 0.1 0.012 14.7 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 EAN31373.1 - 0.00017 21.3 1.4 0.32 10.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EAN31373.1 - 0.0013 19.1 0.3 0.88 9.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EAN31373.1 - 0.0018 18.3 0.2 0.16 12.1 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EAN31373.1 - 0.0021 17.8 0.1 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EAN31373.1 - 0.0099 15.8 3.4 1.9 8.3 0.0 3.4 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 EAN31373.1 - 0.019 14.1 0.9 0.33 10.0 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 EAN31373.1 - 0.02 15.4 0.0 4.2 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAN31373.1 - 0.023 15.2 7.2 0.75 10.3 1.4 2.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EAN31373.1 - 0.026 14.3 3.0 0.82 9.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 EAN31373.1 - 0.027 14.9 0.3 5.8 7.4 0.0 3.3 3 0 0 3 3 2 0 RNA helicase NACHT PF05729.12 EAN31373.1 - 0.03 14.3 1.7 3.4 7.6 0.1 3.0 3 0 0 3 3 3 0 NACHT domain NTPase_1 PF03266.15 EAN31373.1 - 0.064 13.2 1.0 9 6.2 0.1 2.4 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 EAN31373.1 - 0.082 12.1 3.4 0.25 10.5 0.1 2.7 3 0 0 3 3 3 0 NB-ARC domain TrwB_AAD_bind PF10412.9 EAN31373.1 - 0.11 11.4 0.9 1.2 8.0 0.3 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SMC_N PF02463.19 EAN31373.1 - 0.15 11.5 3.4 0.43 10.0 0.5 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EAN31373.1 - 0.16 11.5 0.0 9.4 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EAN31373.1 - 0.18 10.9 0.3 0.98 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.14 EAN31373.1 - 0.19 11.6 1.8 1.3 9.0 0.3 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 EAN31373.1 - 0.24 11.8 0.6 7.4 7.0 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EAN31373.1 - 0.28 10.8 1.1 2.5 7.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 EAN31373.1 - 0.31 11.1 1.3 2 8.4 0.2 2.4 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 EAN31373.1 - 0.4 10.7 4.2 0.19 11.8 0.4 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain FAINT PF04385.15 EAN31374.1 - 8.1e-43 144.4 113.7 1.3e-11 44.4 6.0 10.6 9 1 0 9 9 9 9 Domain of unknown function, DUF529 NpwBP PF12622.7 EAN31374.1 - 0.15 12.8 5.5 9.3 7.1 0.1 3.3 3 0 0 3 3 3 0 mRNA biogenesis factor FAINT PF04385.15 EAN31375.1 - 5.5e-10 39.2 51.1 7.6e-05 22.7 5.8 5.2 5 0 0 5 5 5 4 Domain of unknown function, DUF529 EVI2A PF05399.11 EAN31375.1 - 0.011 15.4 2.3 0.039 13.6 0.6 2.4 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) DUF4366 PF14283.6 EAN31375.1 - 0.09 12.8 0.0 0.09 12.8 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) FAINT PF04385.15 EAN31376.1 - 0.00011 22.2 19.3 0.0043 17.1 3.9 3.5 2 2 2 4 4 4 2 Domain of unknown function, DUF529 DUF4458 PF14660.6 EAN31376.1 - 0.026 14.8 4.3 1.6 9.0 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4458) OppC_N PF12911.7 EAN31376.1 - 0.31 11.1 1.5 0.79 9.7 1.5 1.8 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF5383 PF17355.2 EAN31376.1 - 0.51 10.7 2.6 1.7 9.0 2.6 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5383) Sigma_reg_N PF13800.6 EAN31376.1 - 0.53 10.6 2.9 1.4 9.3 2.9 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Sod_Fe_C PF02777.18 EAN31377.1 - 9.8e-33 112.4 5.5 1.8e-32 111.5 1.2 2.5 2 1 1 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EAN31377.1 - 7e-11 42.4 11.2 5.6e-10 39.6 0.5 3.6 2 1 1 3 3 3 2 Iron/manganese superoxide dismutases, alpha-hairpin domain TrmE_N PF10396.9 EAN31378.1 - 3.1e-30 104.8 0.0 6.7e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 EAN31378.1 - 1.5e-21 77.5 0.7 2.2e-21 77.0 0.7 1.3 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 EAN31378.1 - 2.1e-17 63.2 1.0 7.6e-17 61.4 0.6 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAN31378.1 - 2.8e-06 27.5 1.7 5.6e-06 26.5 0.2 2.5 2 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 EAN31378.1 - 2.9e-05 23.6 0.2 2.9e-05 23.6 0.2 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF3848 PF12959.7 EAN31378.1 - 0.07 13.2 0.6 0.21 11.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) RsgA_GTPase PF03193.16 EAN31378.1 - 0.074 13.0 1.7 2.3 8.1 0.1 2.7 2 2 0 2 2 2 0 RsgA GTPase SNF2_N PF00176.23 EAN31379.1 - 7.5e-52 176.2 4.2 2e-45 155.1 0.5 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EAN31379.1 - 1.9e-20 73.3 6.9 6e-18 65.2 0.1 4.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN31379.1 - 0.00057 19.9 7.9 0.056 13.4 0.0 4.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EAN31379.1 - 0.0052 17.0 0.1 0.012 15.8 0.1 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain CEP44 PF15007.6 EAN31379.1 - 0.061 13.5 0.7 0.27 11.4 0.7 2.2 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 FAINT PF04385.15 EAN31381.1 - 0.0036 17.3 5.7 0.21 11.6 0.0 3.6 4 0 0 4 4 4 2 Domain of unknown function, DUF529 EF_assoc_2 PF08356.12 EAN31382.1 - 0.00077 19.4 1.6 0.11 12.4 0.1 2.6 2 0 0 2 2 2 2 EF hand associated WAC_Acf1_DNA_bd PF10537.9 EAN31382.1 - 0.079 13.5 0.1 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal FAINT PF04385.15 EAN31382.1 - 0.48 10.5 0.0 0.21 11.7 0.9 6.9 8 0 0 8 8 8 0 Domain of unknown function, DUF529 AAA PF00004.29 EAN31383.1 - 1.6e-44 151.5 0.0 4.1e-44 150.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAN31383.1 - 3.9e-10 39.4 0.1 8.8e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EAN31383.1 - 4.7e-08 32.9 0.1 3e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EAN31383.1 - 8.4e-08 32.5 0.0 2.1e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EAN31383.1 - 1.2e-07 31.8 0.2 6.7e-07 29.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAN31383.1 - 7.2e-07 29.7 0.2 0.0004 20.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 EAN31383.1 - 2.1e-05 25.1 0.0 0.0001 22.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 EAN31383.1 - 3.4e-05 24.2 0.7 0.0063 16.8 0.7 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EAN31383.1 - 5.4e-05 22.5 0.0 0.00014 21.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EAN31383.1 - 5.4e-05 23.0 0.0 0.00018 21.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EAN31383.1 - 0.00057 20.2 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 EAN31383.1 - 0.00077 19.4 0.0 0.21 11.5 0.0 3.1 3 0 0 3 3 3 1 NTPase IstB_IS21 PF01695.17 EAN31383.1 - 0.00088 19.1 0.0 0.0047 16.7 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EAN31383.1 - 0.0013 18.2 0.2 0.0047 16.3 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EAN31383.1 - 0.0018 18.5 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EAN31383.1 - 0.0033 17.1 0.1 0.066 12.9 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 EAN31383.1 - 0.0034 16.6 0.1 0.02 14.1 0.0 2.2 2 1 1 3 3 3 1 TIP49 P-loop domain AAA_24 PF13479.6 EAN31383.1 - 0.0045 16.7 0.1 0.013 15.2 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EAN31383.1 - 0.0082 16.2 0.1 0.025 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAN31383.1 - 0.011 16.0 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAN31383.1 - 0.012 15.6 0.2 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EAN31383.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EAN31383.1 - 0.014 14.9 0.0 0.056 12.9 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 EAN31383.1 - 0.015 15.1 0.0 0.055 13.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAN31383.1 - 0.017 14.7 0.2 0.043 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EAN31383.1 - 0.019 14.1 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 EAN31383.1 - 0.025 13.8 0.0 0.072 12.3 0.0 1.8 2 0 0 2 2 1 0 NB-ARC domain AAA_17 PF13207.6 EAN31383.1 - 0.041 14.3 0.1 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EAN31383.1 - 0.05 13.0 0.0 4.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 EAN31383.1 - 0.077 12.7 0.1 0.19 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAN31383.1 - 0.2 12.2 0.3 1.8 9.1 0.0 2.5 3 1 0 3 3 2 0 ABC transporter GvpG PF05120.12 EAN31383.1 - 1.5 8.9 3.9 1 9.4 0.8 2.2 3 0 0 3 3 2 0 Gas vesicle protein G Ribosomal_L30 PF00327.20 EAN31384.1 - 0.0072 16.2 0.1 0.02 14.8 0.1 1.9 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DNA_III_psi PF03603.13 EAN31384.1 - 0.059 13.6 0.0 0.097 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III psi subunit Adenylsucc_synt PF00709.21 EAN31385.1 - 7.3e-154 512.7 0.0 8.8e-154 512.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase PHD PF00628.29 EAN31386.1 - 6.1e-18 64.5 62.9 1.8e-08 34.1 12.8 4.5 2 1 2 4 4 4 3 PHD-finger PHD_2 PF13831.6 EAN31386.1 - 6.2e-06 25.7 18.1 8.5e-05 22.0 1.4 6.6 7 2 0 8 8 8 2 PHD-finger RRM_1 PF00076.22 EAN31387.1 - 1.2e-30 105.2 1.2 2.9e-15 55.9 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAN31387.1 - 3.5e-05 23.8 0.0 0.003 17.7 0.0 3.0 3 1 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 EAN31387.1 - 0.0028 17.5 0.0 1.7 8.5 0.0 4.0 4 2 0 4 4 4 1 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 EAN31387.1 - 0.05 13.4 0.0 8.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain AhpC-TSA PF00578.21 EAN31388.1 - 1.1e-35 122.3 0.0 1.4e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAN31388.1 - 2.5e-15 56.4 0.0 3.2e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EAN31388.1 - 8.9e-10 38.3 0.2 1.8e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EAN31388.1 - 0.018 14.9 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 SCO1/SenC GN3L_Grn1 PF08701.11 EAN31389.1 - 1.4e-09 37.9 13.8 1.4e-09 37.9 13.8 1.3 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase HRDC PF00570.23 EAN31389.1 - 0.031 14.3 0.7 0.092 12.7 0.3 1.8 1 1 1 2 2 2 0 HRDC domain Peripla_BP_4 PF13407.6 EAN31390.1 - 0.0024 17.5 0.0 0.0052 16.4 0.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein domain VCBS PF13517.6 EAN31391.1 - 1.1e-16 61.2 18.7 1.3e-06 28.9 0.1 6.1 5 2 2 7 7 7 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EAN31391.1 - 3.2e-12 46.4 11.0 0.016 15.4 1.5 5.4 5 0 0 5 5 5 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 EAN31391.1 - 0.044 13.2 2.0 16 4.8 0.0 4.6 3 1 2 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region HeLo PF14479.6 EAN31394.1 - 0.017 15.0 0.4 0.028 14.2 0.4 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF4795 PF16043.5 EAN31394.1 - 0.4 10.3 3.6 0.8 9.3 3.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF5344 PF17279.2 EAN31394.1 - 0.69 10.5 13.4 10 6.8 0.1 4.7 4 2 1 5 5 5 0 Family of unknown function (DUF5344) Pre-PUA PF17832.1 EAN31395.1 - 2.5e-23 82.6 0.1 5.9e-23 81.4 0.0 1.6 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 EAN31395.1 - 1.9e-14 53.4 0.0 2.7e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 PUA domain Hydrolase_4 PF12146.8 EAN31396.1 - 1.3e-19 70.4 0.1 6.7e-08 32.1 0.0 3.5 4 0 0 4 4 4 3 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAN31396.1 - 5e-06 26.3 0.1 0.00011 22.0 0.0 2.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold FAINT PF04385.15 EAN31396.1 - 3.5e-05 23.8 21.3 0.0017 18.3 3.9 5.1 4 1 0 4 4 4 2 Domain of unknown function, DUF529 Abhydrolase_6 PF12697.7 EAN31396.1 - 0.0036 17.9 0.0 0.032 14.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EAN31396.1 - 0.0052 16.4 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase APOBEC3 PF18771.1 EAN31396.1 - 0.032 14.3 2.2 3.7 7.7 0.0 3.1 3 0 0 3 3 3 0 APOBEC3 PGAP1 PF07819.13 EAN31396.1 - 0.05 13.3 0.1 0.24 11.1 0.0 2.2 3 0 0 3 3 3 0 PGAP1-like protein EAP30 PF04157.16 EAN31397.1 - 1.6e-32 112.7 0.0 1.9e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family EutK_C PF16365.5 EAN31397.1 - 0.041 13.9 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus DUF3485 PF11984.8 EAN31397.1 - 0.24 11.1 0.2 0.38 10.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) Ribosomal_L16 PF00252.18 EAN31398.1 - 4.4e-17 62.3 0.0 5.9e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CTP_transf_1 PF01148.20 EAN31400.1 - 1.7e-59 201.8 21.8 1.8e-56 191.9 10.3 2.1 2 0 0 2 2 2 2 Cytidylyltransferase family Fer2 PF00111.27 EAN31401.1 - 1.8e-15 56.6 1.2 3e-15 55.9 1.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ribosomal_S19 PF00203.21 EAN31402.1 - 3.5e-33 113.3 0.2 5e-33 112.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ctr PF04145.15 EAN31403.1 - 1.5e-09 38.6 19.0 2.7e-07 31.3 11.3 4.7 2 2 1 3 3 3 2 Ctr copper transporter family DUF485 PF04341.12 EAN31403.1 - 1.1 9.2 5.7 2.3 8.2 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Phage_holin_4_1 PF05105.12 EAN31403.1 - 2.6 8.2 5.2 3.9 7.7 5.2 1.1 1 0 0 1 1 1 0 Bacteriophage holin family ABC2_membrane_2 PF12679.7 EAN31403.1 - 3.3 6.9 5.8 5.5 6.2 5.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2070 PF09843.9 EAN31403.1 - 4.5 5.4 6.8 6.1 5.0 6.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ycf15 PF10705.9 EAN31405.1 - 0.04 14.1 0.1 0.073 13.2 0.1 1.5 1 1 0 1 1 1 0 Chloroplast protein precursor Ycf15 putative Tetraspanin PF00335.20 EAN31405.1 - 0.065 12.9 6.9 0.086 12.5 6.9 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF3681 PF12442.8 EAN31405.1 - 0.37 11.3 2.5 7 7.2 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3681) CBF PF03914.17 EAN31406.1 - 1.9e-15 57.3 1.3 5e-15 55.9 1.3 1.7 1 0 0 1 1 1 1 CBF/Mak21 family MCM PF00493.23 EAN31409.1 - 2e-78 262.5 0.1 3.6e-78 261.7 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EAN31409.1 - 4.5e-19 68.7 1.0 1.7e-18 66.8 1.0 2.1 1 1 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 EAN31409.1 - 1.5e-12 47.5 4.1 4.1e-11 42.8 4.1 2.6 1 1 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 EAN31409.1 - 2.8e-09 37.1 0.0 7.9e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EAN31409.1 - 1.4e-08 34.4 0.3 6.8e-07 28.9 0.3 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 EAN31409.1 - 3.1e-06 27.7 2.8 3.1e-06 27.7 2.8 2.6 2 2 0 2 2 2 1 MCM N-terminal domain AAA_3 PF07726.11 EAN31409.1 - 0.00095 19.0 0.0 0.0027 17.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAN31409.1 - 0.0022 17.7 0.0 0.017 14.9 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF2408 PF10303.9 EAN31409.1 - 0.0046 17.5 3.4 1.3 9.6 1.2 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2408) CRA PF06589.11 EAN31409.1 - 3.8 7.6 7.8 1.3 9.1 0.4 2.8 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) RRM_1 PF00076.22 EAN31411.1 - 4e-39 132.3 0.0 1.3e-19 69.8 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAN31411.1 - 0.011 15.3 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAN31411.1 - 0.013 15.5 0.1 0.39 10.8 0.0 2.3 2 1 0 2 2 2 0 Limkain b1 RRM_occluded PF16842.5 EAN31411.1 - 0.051 13.4 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif GDP_Man_Dehyd PF16363.5 EAN31411.1 - 0.083 12.3 0.1 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Auto_anti-p27 PF06677.12 EAN31412.1 - 2.8e-14 53.0 6.4 4.7e-14 52.3 6.4 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Thioredoxin PF00085.20 EAN31413.1 - 2.5e-12 46.7 0.1 4e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EAN31413.1 - 1.6e-08 33.9 0.1 2e-08 33.5 0.1 1.0 1 0 0 1 1 1 1 Phosducin tRNA_m1G_MT PF01746.21 EAN31414.1 - 8.6e-27 94.1 0.0 1.1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase CAF1 PF04857.20 EAN31414.1 - 0.048 12.8 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease Peptidase_M24 PF00557.24 EAN31415.1 - 1.4e-50 171.9 0.0 1.8e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EAN31415.1 - 7e-13 48.7 9.5 1.6e-12 47.5 9.5 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EAN31415.1 - 0.0014 18.6 5.6 0.0044 17.1 5.6 1.9 1 0 0 1 1 1 1 MYND finger DUF866 PF05907.13 EAN31415.1 - 0.072 13.0 0.8 0.13 12.2 0.8 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) ELYS PF13934.6 EAN31415.1 - 0.082 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex assembly Prok-RING_4 PF14447.6 EAN31415.1 - 0.2 11.5 5.0 0.07 13.0 1.6 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RMI1_N PF08585.12 EAN31416.1 - 1.9e-08 34.4 0.1 1.2e-07 31.8 0.0 2.1 1 1 1 2 2 2 1 RecQ mediated genome instability protein NBD94 PF16830.5 EAN31416.1 - 0.023 15.1 2.7 0.023 15.1 2.7 1.9 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH Sorting_nexin PF03700.13 EAN31416.1 - 0.05 14.2 0.9 0.096 13.2 0.9 1.5 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain NTP_transf_2 PF01909.23 EAN31417.1 - 1.2e-06 28.7 0.0 5.1e-06 26.7 0.0 2.2 1 1 1 2 2 2 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 EAN31417.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 EAN31417.1 - 0.02 15.0 0.1 0.23 11.6 0.0 2.8 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Cpn60_TCP1 PF00118.24 EAN31418.1 - 2.3e-94 316.8 10.4 3e-94 316.4 10.4 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_S5_C PF03719.15 EAN31419.1 - 1.3e-10 40.6 0.0 3e-09 36.2 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EAN31419.1 - 1.7e-06 27.9 1.2 0.002 18.1 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein S5, N-terminal domain Histone PF00125.24 EAN31423.1 - 1.5e-17 64.2 0.4 1.7e-17 64.0 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 EAN31423.1 - 0.004 17.6 0.0 0.0073 16.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EAN31423.1 - 0.02 15.1 0.2 0.04 14.2 0.0 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 EAN31423.1 - 0.13 12.3 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein PHD PF00628.29 EAN31424.1 - 1.8e-11 43.7 8.4 1.8e-11 43.7 8.4 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 EAN31424.1 - 9.5e-08 32.3 8.5 9.5e-08 32.3 8.5 2.7 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EAN31424.1 - 6.3e-07 29.6 4.3 6.3e-07 29.6 4.3 2.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAN31424.1 - 1.2e-06 28.3 9.3 1.2e-06 28.3 9.3 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAN31424.1 - 1.3e-06 28.2 6.6 1.3e-06 28.2 6.6 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAN31424.1 - 3.2e-06 26.9 6.9 3.2e-06 26.9 6.9 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAN31424.1 - 1.2e-05 25.1 7.0 1.2e-05 25.1 7.0 2.7 2 1 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EAN31424.1 - 1.8e-05 24.5 6.5 1.8e-05 24.5 6.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EAN31424.1 - 0.0029 17.6 1.8 0.0029 17.6 1.8 3.9 4 0 0 4 4 4 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EAN31424.1 - 0.014 15.4 1.3 0.014 15.4 1.3 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger CNDH2_M PF16869.5 EAN31424.1 - 0.024 15.3 0.5 0.024 15.3 0.5 5.6 4 1 0 5 5 3 0 PF16858 PHD_2 PF13831.6 EAN31424.1 - 0.25 10.9 3.0 0.79 9.3 3.0 1.9 1 0 0 1 1 1 0 PHD-finger zf-RING_6 PF14835.6 EAN31424.1 - 1.3 9.0 5.3 1.5 8.8 2.6 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-HC5HC2H PF13771.6 EAN31424.1 - 2.7 8.3 9.6 1.5 9.2 1.3 3.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EAN31424.1 - 6.9 6.9 10.7 3.4 7.9 2.0 3.1 2 1 0 2 2 2 0 PHD-zinc-finger like domain zf-RING_11 PF17123.5 EAN31424.1 - 8.1 6.3 18.9 0.2 11.4 7.3 3.2 3 0 0 3 3 3 0 RING-like zinc finger FANCI_S1-cap PF14674.6 EAN31425.1 - 0.047 13.8 0.8 0.13 12.3 0.8 1.8 1 0 0 1 1 1 0 FANCI solenoid 1 cap RrnaAD PF00398.20 EAN31426.1 - 4.2e-25 88.3 0.2 8.6e-22 77.5 0.0 2.1 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase WD40 PF00400.32 EAN31430.1 - 6.8e-07 29.9 6.7 0.001 19.8 0.0 4.9 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN31430.1 - 1.1e-06 28.8 0.3 0.29 11.4 0.0 3.9 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 EAN31431.1 - 4.9e-07 30.0 10.2 1.1e-06 28.9 10.2 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain GDI PF00996.18 EAN31432.1 - 4.2e-21 75.0 16.0 4.1e-10 38.8 0.1 4.7 4 1 0 4 4 4 3 GDP dissociation inhibitor Latarcin PF10279.9 EAN31433.1 - 0.029 14.8 0.0 5.1 7.6 3.1 3.0 3 2 0 3 3 3 0 Latarcin precursor Eaf7 PF07904.13 EAN31433.1 - 0.39 11.1 3.1 2.2 8.7 3.1 2.4 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 SNRNP27 PF08648.12 EAN31435.1 - 1.4e-25 89.1 1.1 1.4e-25 89.1 1.1 2.1 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins FAINT PF04385.15 EAN31436.1 - 2.5e-25 88.3 16.7 1.8e-07 31.1 0.2 6.4 5 1 1 6 6 6 5 Domain of unknown function, DUF529 T4_Gp59_C PF08994.10 EAN31437.1 - 0.045 14.4 0.3 0.19 12.3 0.1 2.0 2 0 0 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase C-term FAINT PF04385.15 EAN31437.1 - 0.074 13.1 0.2 0.96 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31438.1 - 0.00088 19.3 0.4 0.87 9.7 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 SNF2_N PF00176.23 EAN31440.1 - 2.4e-44 151.5 8.6 1.4e-36 126.0 0.9 3.0 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EAN31440.1 - 1.3e-16 60.9 2.6 2e-16 60.3 0.3 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN31440.1 - 0.00058 19.9 0.0 0.00058 19.9 0.0 3.1 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAN31440.1 - 0.00078 18.7 2.7 0.01 15.1 0.5 2.5 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EAN31440.1 - 0.0014 18.4 0.0 0.005 16.6 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAN31440.1 - 0.0093 16.2 0.2 0.055 13.7 0.0 2.4 3 0 0 3 3 3 1 AAA domain Snf7 PF03357.21 EAN31440.1 - 0.28 10.8 3.1 0.74 9.4 3.1 1.8 1 0 0 1 1 1 0 Snf7 Cpn60_TCP1 PF00118.24 EAN31441.1 - 1.5e-177 591.2 0.7 1.7e-177 591.0 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HTH_Mga PF08280.11 EAN31442.1 - 0.01 15.9 0.7 0.027 14.5 0.1 2.1 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Keratin_matx PF04579.12 EAN31442.1 - 0.029 14.7 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 Keratin, high-sulphur matrix protein IF2_N PF04760.15 EAN31442.1 - 0.1 12.4 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region NUMOD1 PF07453.13 EAN31442.1 - 0.12 12.6 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 NUMOD1 domain HTH_25 PF13413.6 EAN31442.1 - 0.2 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Tubulin PF00091.25 EAN31445.1 - 5.3e-67 225.9 0.0 8.8e-67 225.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAN31445.1 - 6.8e-50 168.5 0.5 1.1e-49 167.8 0.1 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EAN31445.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Ribosomal_L32e PF01655.18 EAN31446.1 - 8e-42 142.1 0.9 9.5e-42 141.8 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 CitT PF12431.8 EAN31446.1 - 0.17 12.3 0.5 14 6.2 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator FAINT PF04385.15 EAN31447.1 - 3.2e-06 27.1 0.5 5.6e-06 26.3 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 SH3_1 PF00018.28 EAN31447.1 - 0.0083 15.7 0.2 0.016 14.8 0.2 1.4 1 0 0 1 1 1 1 SH3 domain FAINT PF04385.15 EAN31448.1 - 3.5e-16 59.0 9.6 4.7e-09 36.2 1.1 2.6 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31449.1 - 5.4e-17 61.6 11.6 4.9e-09 36.1 3.8 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF4252 PF14060.6 EAN31449.1 - 0.29 11.0 7.5 1.3 8.9 0.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4252) FAINT PF04385.15 EAN31450.1 - 9.8e-05 22.3 2.9 9.8e-05 22.3 2.9 2.8 3 0 0 3 3 3 1 Domain of unknown function, DUF529 F420_ligase PF01996.16 EAN31450.1 - 0.16 11.3 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase FAINT PF04385.15 EAN31451.1 - 7.6e-11 41.9 11.2 9.8e-10 38.4 5.5 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 PH_16 PF17838.1 EAN31451.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 PH domain FAINT PF04385.15 EAN31452.1 - 1.5e-12 47.4 11.9 7.8e-07 29.1 0.7 3.2 3 1 0 3 3 3 2 Domain of unknown function, DUF529 LRR_8 PF13855.6 EAN31452.1 - 0.22 11.3 8.0 10 6.0 0.6 2.5 1 1 0 1 1 1 0 Leucine rich repeat LRR_4 PF12799.7 EAN31452.1 - 0.47 11.0 9.8 6.2 7.4 2.9 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) FAINT PF04385.15 EAN31453.1 - 2.7e-13 49.8 18.5 5.6e-08 32.7 8.7 2.5 2 1 0 2 2 2 2 Domain of unknown function, DUF529 Es2 PF09751.9 EAN31453.1 - 0.00015 21.6 7.8 0.00015 21.6 7.8 2.3 2 0 0 2 2 2 1 Nuclear protein Es2 IHABP4_N PF16174.5 EAN31453.1 - 0.0028 18.3 6.4 0.0035 18.0 0.1 2.6 2 1 0 2 2 2 1 Intracellular hyaluronan-binding protein 4 N-terminal DUF4252 PF14060.6 EAN31453.1 - 0.011 15.6 7.0 0.028 14.3 2.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4252) FAINT PF04385.15 EAN31454.1 - 2.9e-09 36.9 14.5 1.6e-05 24.9 7.0 2.7 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31455.1 - 4.5e-15 55.5 9.8 7.2e-08 32.4 0.6 2.7 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31456.1 - 5.4e-05 23.2 7.4 8.5e-05 22.5 7.0 1.7 1 1 0 1 1 1 1 Domain of unknown function, DUF529 DUF4330 PF14221.6 EAN31456.1 - 0.02 15.1 0.2 0.027 14.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) PHA_gran_rgn PF09650.10 EAN31456.1 - 0.2 12.0 1.8 5 7.5 1.2 2.6 1 1 1 2 2 2 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) RabGAP-TBC PF00566.18 EAN31457.1 - 4.6e-11 42.8 0.0 4.6e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4653 PF15546.6 EAN31457.1 - 0.1 12.2 11.5 1.4 8.5 5.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4653) Adaptin_N PF01602.20 EAN31458.1 - 2.8e-19 69.1 15.2 2.8e-19 69.1 15.2 2.3 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 EAN31458.1 - 0.0016 18.5 2.5 0.0016 18.5 2.5 3.4 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAN31458.1 - 0.0028 17.8 0.1 0.029 14.6 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat DUF2684 PF10885.8 EAN31458.1 - 0.43 10.7 3.1 2.6 8.2 0.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2684) SPC22 PF04573.12 EAN31460.1 - 2.7e-33 114.9 0.3 3.1e-33 114.7 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Prefoldin_2 PF01920.20 EAN31461.1 - 8e-07 29.0 4.3 1.1e-06 28.6 4.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Bac_DNA_binding PF00216.21 EAN31462.1 - 2.7e-19 69.1 0.1 4.4e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 EAN31462.1 - 3.5e-07 30.4 0.4 4.5e-07 30.0 0.4 1.2 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 EAN31462.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 CTP_transf_like PF01467.26 EAN31464.1 - 1.3e-05 25.4 0.2 4e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 Cytidylyltransferase-like zf-A20 PF01754.16 EAN31465.1 - 1.5e-10 40.8 12.6 1.5e-10 40.8 12.6 2.7 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 EAN31465.1 - 2.4e-09 37.2 5.9 2.4e-09 37.2 5.9 2.6 2 1 0 2 2 2 1 AN1-like Zinc finger SprA-related PF12118.8 EAN31465.1 - 0.017 14.3 2.1 0.021 14.0 2.1 1.1 1 0 0 1 1 1 0 SprA-related family C1_2 PF03107.16 EAN31465.1 - 0.22 11.8 13.9 0.075 13.4 2.3 2.4 2 0 0 2 2 2 0 C1 domain Ribosomal_L37ae PF01780.19 EAN31465.1 - 1.5 8.9 8.4 5.5 7.2 0.1 3.2 3 1 1 4 4 4 0 Ribosomal L37ae protein family FAINT PF04385.15 EAN31467.1 - 9.6e-08 32.0 3.7 0.005 16.9 0.6 2.9 2 1 1 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31468.1 - 9.9e-06 25.5 17.6 0.0049 16.9 0.9 4.1 4 0 0 4 4 4 3 Domain of unknown function, DUF529 CHASE9 PF17153.4 EAN31468.1 - 0.054 13.6 0.9 0.44 10.7 0.0 2.7 4 0 0 4 4 4 0 Periplasmic sensor domain, extracellular WD40 PF00400.32 EAN31469.1 - 2.5e-11 43.9 3.9 4.5e-05 24.1 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-A20 PF01754.16 EAN31469.1 - 3.9e-10 39.5 12.6 3.9e-10 39.5 12.6 2.7 3 0 0 3 3 3 1 A20-like zinc finger zf-AN1 PF01428.16 EAN31469.1 - 8.2e-09 35.5 6.0 8.2e-09 35.5 6.0 2.7 2 1 0 2 2 2 1 AN1-like Zinc finger SprA-related PF12118.8 EAN31469.1 - 0.024 13.8 2.3 0.039 13.1 2.3 1.3 1 0 0 1 1 1 0 SprA-related family C1_2 PF03107.16 EAN31469.1 - 0.45 10.9 12.7 0.22 11.8 2.3 2.7 2 0 0 2 2 2 0 C1 domain Ribosomal_L37ae PF01780.19 EAN31469.1 - 3.7 7.7 6.2 17 5.6 0.2 2.9 3 0 0 3 3 3 0 Ribosomal L37ae protein family WD40 PF00400.32 EAN31470.1 - 0.00067 20.4 5.9 0.22 12.5 0.4 4.7 5 1 0 5 5 5 2 WD domain, G-beta repeat Holin_SPP1 PF04688.13 EAN31471.1 - 1.1 9.5 7.4 0.27 11.4 0.7 2.5 2 0 0 2 2 2 0 SPP1 phage holin Pkinase PF00069.25 EAN31474.1 - 3e-69 233.3 0.1 3.9e-69 233.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN31474.1 - 2.9e-38 131.7 0.0 3.9e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAN31474.1 - 1.2e-10 41.2 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAN31474.1 - 0.00071 19.0 0.1 0.0015 17.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAN31474.1 - 0.0082 15.8 0.1 0.02 14.5 0.0 1.5 1 1 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EAN31474.1 - 0.017 14.7 0.3 0.26 10.9 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAN31474.1 - 0.046 12.5 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase AvrM_N PF18247.1 EAN31475.1 - 0.029 14.3 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain YejG PF13989.6 EAN31475.1 - 0.13 12.7 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 YejG-like protein ATP_bind_3 PF01171.20 EAN31476.1 - 0.0027 17.5 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 PP-loop family Nop14 PF04147.12 EAN31476.1 - 0.25 9.5 28.3 0.43 8.7 28.3 1.4 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L1 PF00687.21 EAN31477.1 - 4.5e-42 144.1 1.3 5.5e-42 143.8 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Tnp_22_trimer PF17489.2 EAN31477.1 - 0.037 14.0 0.3 0.41 10.7 0.1 2.3 2 0 0 2 2 2 0 L1 transposable element trimerization domain FAINT PF04385.15 EAN31478.1 - 0.00045 20.2 20.1 0.011 15.7 1.4 4.5 3 1 0 3 3 3 3 Domain of unknown function, DUF529 PDZ_assoc PF10600.9 EAN31479.1 - 2.1 9.2 5.7 8.5 7.3 1.0 2.5 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors FAINT PF04385.15 EAN31480.1 - 8.8e-06 25.7 0.8 8.8e-06 25.7 0.8 3.8 4 0 0 4 4 4 1 Domain of unknown function, DUF529 POB3_N PF17292.2 EAN31481.1 - 1.2e-26 92.9 5.9 8e-26 90.3 2.0 3.1 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 EAN31481.1 - 1.8e-22 79.5 2.0 7.5e-22 77.6 0.4 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 EAN31481.1 - 3.8e-17 62.0 0.2 3.6e-16 58.8 0.0 2.8 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) LCM PF04072.14 EAN31482.1 - 5e-13 49.4 0.0 6.1e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase LCM PF04072.14 EAN31484.1 - 3.1e-09 37.0 0.0 3.3e-09 37.0 0.0 1.0 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase LCM PF04072.14 EAN31486.1 - 1.3e-20 74.1 0.0 2.6e-20 73.1 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase LCM PF04072.14 EAN31487.1 - 4.8e-18 65.8 0.0 8.4e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase FAINT PF04385.15 EAN31488.1 - 0.0012 18.9 9.0 0.21 11.6 0.2 2.7 2 1 0 2 2 2 2 Domain of unknown function, DUF529 DUF1986 PF09342.11 EAN31488.1 - 0.012 16.0 0.1 0.018 15.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) PUF PF00806.19 EAN31489.1 - 1.7e-10 40.0 10.7 0.00088 18.8 0.1 5.6 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Abhydrolase_1 PF00561.20 EAN31490.1 - 5.5e-05 22.9 0.1 0.005 16.5 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAN31490.1 - 0.0032 18.1 0.0 0.0043 17.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAN31490.1 - 0.0034 16.7 0.0 0.99 8.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 EAN31490.1 - 0.13 11.0 0.0 0.31 9.7 0.0 1.6 2 0 0 2 2 2 0 Ndr family Pkinase PF00069.25 EAN31491.1 - 1.7e-48 165.3 0.1 1.3e-47 162.4 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN31491.1 - 8e-28 97.4 0.0 2.7e-27 95.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAN31491.1 - 1.9e-05 23.7 0.0 3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAN31491.1 - 0.0058 16.6 0.0 0.38 10.6 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family TF_Zn_Ribbon PF08271.12 EAN31491.1 - 0.022 14.3 0.1 0.068 12.7 0.1 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding Kinase-like PF14531.6 EAN31491.1 - 0.037 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EAN31491.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-ribbon_3 PF13248.6 EAN31491.1 - 0.11 11.9 1.2 0.25 10.8 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 EAN31491.1 - 0.33 10.7 2.8 3.4 7.5 0.2 2.7 2 0 0 2 2 2 0 A2L zinc ribbon domain C2 PF00168.30 EAN31492.1 - 1.1e-09 38.5 0.0 1.7e-05 25.0 0.0 3.0 2 0 0 2 2 2 2 C2 domain GIDA PF01134.22 EAN31493.1 - 1e-126 423.2 0.3 5.7e-126 420.8 0.3 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EAN31493.1 - 6.9e-34 117.9 2.7 3.7e-28 99.2 0.4 2.6 1 1 1 2 2 2 2 GidA associated domain FAD_oxidored PF12831.7 EAN31493.1 - 3.9e-06 26.5 0.6 7.2e-06 25.6 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAN31493.1 - 0.00073 18.9 0.0 0.003 16.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAN31493.1 - 0.0016 17.7 0.1 0.0091 15.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAN31493.1 - 0.0056 17.2 0.9 0.023 15.3 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAN31493.1 - 0.0084 15.2 0.6 0.014 14.5 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EAN31493.1 - 0.045 12.4 0.1 0.45 9.2 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EAN31493.1 - 0.061 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FPRL1_inhibitor PF16104.5 EAN31493.1 - 0.11 12.6 0.3 2.7 8.2 0.1 2.8 4 0 0 4 4 4 0 Formyl peptide receptor-like 1 inhibitory protein SUI1 PF01253.22 EAN31494.1 - 8.8e-24 83.8 0.6 1.1e-23 83.5 0.6 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 ssDNA_TraI_N PF18272.1 EAN31494.1 - 0.0085 16.1 0.0 0.9 9.6 0.0 2.1 2 0 0 2 2 2 2 single-stranded DNA binding TraI N-terminal subdomain Img2 PF05046.14 EAN31494.1 - 0.055 13.8 0.3 0.075 13.3 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Snf7 PF03357.21 EAN31495.1 - 5.4e-13 48.9 5.3 6.7e-13 48.6 5.3 1.1 1 0 0 1 1 1 1 Snf7 Med2 PF11214.8 EAN31495.1 - 0.094 12.9 4.1 0.071 13.3 2.0 1.9 1 1 1 2 2 2 0 Mediator complex subunit 2 HalX PF08663.10 EAN31495.1 - 0.11 12.8 3.0 0.13 12.6 0.4 2.0 2 0 0 2 2 2 0 HalX domain DUF1189 PF06691.11 EAN31496.1 - 2.4 7.7 6.5 4.7 6.7 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) FAINT PF04385.15 EAN31497.1 - 3.7e-59 196.7 69.8 1.3e-07 31.6 2.6 11.5 11 0 0 11 11 11 11 Domain of unknown function, DUF529 Hid1 PF12722.7 EAN31497.1 - 9.7 4.2 7.7 15 3.6 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein XPG_I PF00867.18 EAN31499.1 - 4e-22 78.4 3.4 1.7e-20 73.2 0.3 3.1 2 1 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EAN31499.1 - 4.6e-14 52.7 0.3 4.5e-13 49.5 0.3 2.6 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EAN31499.1 - 0.00012 21.7 0.0 0.00033 20.2 0.0 1.8 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.20 EAN31499.1 - 0.0014 19.1 5.2 0.0026 18.3 0.0 3.5 3 1 1 4 4 4 1 5'-3' exonuclease, C-terminal SAM fold R_equi_Vir PF05526.11 EAN31499.1 - 0.099 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein zf-met PF12874.7 EAN31500.1 - 1.2e-05 25.5 0.4 4.8e-05 23.6 0.4 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EAN31500.1 - 9.2e-05 22.6 0.9 0.00034 20.8 0.9 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding NUFIP1 PF10453.9 EAN31500.1 - 0.00011 21.9 0.5 0.00031 20.5 0.5 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_4 PF13894.6 EAN31500.1 - 0.0035 18.1 0.8 0.062 14.2 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger EF-hand_5 PF13202.6 EAN31500.1 - 0.092 12.3 0.3 0.22 11.1 0.3 1.7 1 0 0 1 1 1 0 EF hand Sec16 PF12932.7 EAN31500.1 - 0.13 12.9 0.1 0.37 11.4 0.0 1.8 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region zf-C2H2 PF00096.26 EAN31500.1 - 0.17 12.4 1.6 0.76 10.4 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF5106 PF17127.4 EAN31501.1 - 0.0053 17.0 0.2 0.076 13.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5106) P66_CC PF16563.5 EAN31501.1 - 0.063 12.9 0.1 0.22 11.2 0.1 1.9 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 ENTH PF01417.20 EAN31501.1 - 2.8 8.0 13.6 1.6 8.8 1.6 4.0 3 1 0 4 4 4 0 ENTH domain WD40 PF00400.32 EAN31503.1 - 2.5e-37 126.2 9.5 2.1e-06 28.3 0.0 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN31503.1 - 1.4e-11 44.6 0.5 0.0084 16.4 0.0 5.8 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAN31503.1 - 1.8e-08 34.1 1.5 3.9e-08 33.0 0.6 2.0 1 1 1 2 2 2 2 WD40-like domain AAA PF00004.29 EAN31504.1 - 6.2e-43 146.4 0.0 1.2e-42 145.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAN31504.1 - 1.7e-11 43.7 0.0 3.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EAN31504.1 - 2e-07 30.8 0.1 4.5e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EAN31504.1 - 7.6e-07 29.2 0.1 1.8e-05 24.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAN31504.1 - 7.8e-07 29.6 0.1 0.00041 20.8 0.0 2.6 2 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 EAN31504.1 - 8.5e-07 28.8 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EAN31504.1 - 1.7e-06 28.3 0.0 5.6e-06 26.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EAN31504.1 - 8.9e-05 22.8 0.1 0.0056 17.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAN31504.1 - 0.00032 21.3 0.0 0.0012 19.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain Med9 PF07544.13 EAN31504.1 - 0.00042 20.4 2.3 0.0038 17.3 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 TIP49 PF06068.13 EAN31504.1 - 0.00053 19.3 0.0 0.0012 18.1 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 EAN31504.1 - 0.00086 18.9 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EAN31504.1 - 0.00088 19.6 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.13 EAN31504.1 - 0.00092 18.4 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EAN31504.1 - 0.0012 19.0 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EAN31504.1 - 0.0016 18.5 0.0 0.006 16.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 EAN31504.1 - 0.0016 18.2 0.1 0.0047 16.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 EAN31504.1 - 0.0022 18.3 0.2 0.0072 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EAN31504.1 - 0.0033 17.2 0.0 0.0081 15.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EAN31504.1 - 0.0039 16.6 0.2 0.012 15.0 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EAN31504.1 - 0.006 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EAN31504.1 - 0.0094 15.8 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EAN31504.1 - 0.014 15.3 0.2 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Med4 PF10018.9 EAN31504.1 - 0.029 14.1 1.2 0.087 12.5 0.5 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Sigma54_activat PF00158.26 EAN31504.1 - 0.035 13.8 0.0 0.13 11.9 0.0 1.9 2 1 0 2 2 1 0 Sigma-54 interaction domain Type2_restr_D3 PF16902.5 EAN31504.1 - 0.035 14.0 0.6 0.1 12.5 0.6 1.7 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Parvo_NS1 PF01057.17 EAN31504.1 - 0.038 13.1 0.0 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Adeno_IVa2 PF02456.15 EAN31504.1 - 0.091 11.5 0.1 0.28 9.9 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATPase PF06745.13 EAN31504.1 - 0.093 12.1 0.9 0.25 10.7 0.0 2.1 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 EAN31504.1 - 0.11 12.1 0.4 0.24 10.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 EAN31504.1 - 0.14 12.7 0.2 1.7 9.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.6 EAN31504.1 - 0.14 12.2 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain LURAP PF14854.6 EAN31504.1 - 0.19 11.7 0.6 0.4 10.6 0.6 1.5 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF3287 PF11690.8 EAN31504.1 - 0.2 11.4 1.1 0.65 9.7 1.2 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF3287) SKI PF01202.22 EAN31504.1 - 0.23 11.6 1.2 0.58 10.3 0.0 2.2 2 1 1 3 3 2 0 Shikimate kinase PEARLI-4 PF05278.12 EAN31504.1 - 0.25 10.9 2.7 0.1 12.2 0.3 1.5 2 0 0 2 2 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) AAA_11 PF13086.6 EAN31504.1 - 0.26 11.1 2.7 0.59 9.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain DivIC PF04977.15 EAN31504.1 - 0.26 11.1 3.4 1.4 8.8 1.6 2.6 3 0 0 3 3 2 0 Septum formation initiator ATPase_2 PF01637.18 EAN31504.1 - 0.37 10.7 3.3 1.4 8.8 0.0 2.9 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea BLOC1_2 PF10046.9 EAN31504.1 - 0.56 10.5 4.5 0.45 10.8 0.6 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 VitD-bind_III PF09164.10 EAN31506.1 - 0.061 13.3 0.4 0.087 12.8 0.4 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III INCENP_ARK-bind PF03941.15 EAN31508.1 - 0.0011 18.9 0.4 0.012 15.5 0.0 2.5 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region SdpI PF13630.6 EAN31509.1 - 3.7 7.8 9.4 0.2 11.8 2.5 2.4 2 1 0 2 2 2 0 SdpI/YhfL protein family RBFA PF02033.18 EAN31510.1 - 3.6e-10 40.2 0.0 7.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Ribosome-binding factor A DUF5359 PF17313.2 EAN31510.1 - 5.8 7.0 12.3 0.12 12.3 3.8 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5359) MMR_HSR1 PF01926.23 EAN31511.1 - 1.4e-15 57.4 0.2 3e-15 56.3 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAN31511.1 - 8.6e-08 31.8 1.9 5.5e-07 29.1 0.1 2.6 3 0 0 3 3 3 1 AIG1 family FeoB_N PF02421.18 EAN31511.1 - 9.9e-07 28.4 0.3 2.2e-06 27.3 0.3 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAN31511.1 - 3.2e-06 27.2 1.5 7.5e-06 26.0 0.1 2.2 2 1 1 3 3 3 1 RsgA GTPase SRPRB PF09439.10 EAN31511.1 - 0.00015 21.3 0.1 0.0003 20.3 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EAN31511.1 - 0.00042 20.5 0.2 0.002 18.3 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EAN31511.1 - 0.003 17.6 8.0 0.03 14.4 0.2 3.2 2 2 1 3 3 3 2 Dynamin family Arf PF00025.21 EAN31511.1 - 0.036 13.5 0.4 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 EAN31511.1 - 0.04 14.5 2.8 0.52 10.9 0.8 3.1 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 EAN31511.1 - 0.043 13.4 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Ras family Acetyltransf_1 PF00583.25 EAN31513.1 - 6.2e-08 32.9 0.0 7.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EAN31513.1 - 1e-06 28.6 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EAN31513.1 - 0.00031 21.1 0.1 0.00042 20.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAN31513.1 - 0.0014 18.6 0.1 0.0015 18.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EAN31513.1 - 0.079 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S10 PF00338.22 EAN31514.1 - 1.2e-26 92.8 0.0 1.4e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 EAN31514.1 - 0.059 14.2 0.0 0.1 13.4 0.0 1.3 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain IMCp PF12314.8 EAN31515.1 - 5.7e-28 97.0 44.3 8.7e-27 93.3 34.7 2.2 1 1 1 2 2 2 2 Inner membrane complex protein Tash_PEST PF07708.11 EAN31516.1 - 1.5e-05 25.0 6.4 1.5e-05 25.0 6.4 3.3 3 0 0 3 3 3 1 Tash protein PEST motif FAINT PF04385.15 EAN31516.1 - 0.0094 16.0 0.3 0.0094 16.0 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function, DUF529 MKT1_C PF12246.8 EAN31517.1 - 5.7e-40 137.1 0.2 8.6e-40 136.5 0.2 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EAN31517.1 - 2.5e-20 72.6 0.1 3.7e-19 68.9 0.0 2.8 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 EAN31517.1 - 3.7e-06 27.2 0.0 1.1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EAN31517.1 - 0.012 16.1 0.0 0.04 14.4 0.0 1.9 1 0 0 1 1 1 0 XPG N-terminal domain GTP_EFTU PF00009.27 EAN31518.1 - 1e-36 126.3 0.0 1.7e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EAN31518.1 - 5.6e-21 74.4 0.0 1.5e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 EAN31518.1 - 3.6e-14 52.6 0.0 9.7e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFTUD2 PF16004.5 EAN31518.1 - 2.9e-10 40.8 11.8 8.1e-09 36.1 11.8 2.3 1 1 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus GTP_EFTU_D2 PF03144.25 EAN31518.1 - 8.9e-08 32.4 0.0 2.1e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EAN31518.1 - 4.3e-05 23.5 0.0 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EAN31518.1 - 0.00068 19.7 0.0 0.0018 18.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Laminin_G_3 PF13385.6 EAN31519.1 - 0.00094 19.4 0.0 0.014 15.6 0.0 2.1 1 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily CLP_protease PF00574.23 EAN31520.1 - 6.8e-67 224.9 0.1 8.3e-67 224.6 0.1 1.1 1 0 0 1 1 1 1 Clp protease HSP20 PF00011.21 EAN31521.1 - 1.9e-10 40.8 0.0 3.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EAN31521.1 - 0.0009 18.7 0.0 0.0059 16.1 0.0 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Thioredoxin_3 PF13192.6 EAN31521.1 - 0.072 13.2 0.8 0.5 10.4 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin domain ZapA PF05164.13 EAN31521.1 - 0.18 12.3 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Cell division protein ZapA Rad51 PF08423.11 EAN31522.1 - 6.6e-100 333.6 0.0 8.5e-100 333.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EAN31522.1 - 1.7e-08 34.3 0.0 5e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain RecA PF00154.21 EAN31522.1 - 2.2e-07 30.6 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 EAN31522.1 - 0.00015 21.2 1.5 0.00031 20.2 0.6 2.1 2 1 0 2 2 2 1 KaiC RNA_pol_A_CTD PF03118.15 EAN31522.1 - 0.0011 18.7 0.3 0.0029 17.3 0.3 1.7 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain AAA_22 PF13401.6 EAN31522.1 - 0.0036 17.6 0.1 0.0061 16.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EAN31522.1 - 0.0057 17.1 0.0 0.02 15.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HHH_5 PF14520.6 EAN31522.1 - 0.021 15.4 0.3 0.093 13.4 0.1 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain HEPN_RiboL-PSP PF18735.1 EAN31522.1 - 0.042 13.8 3.6 0.071 13.0 3.3 1.7 1 1 0 1 1 1 0 RiboL-PSP-HEPN Baculo_IE-1 PF05290.11 EAN31522.1 - 0.14 12.1 1.9 1.2 9.0 0.4 2.7 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Hydrolase_4 PF12146.8 EAN31524.1 - 3.5e-22 78.9 0.0 1.1e-19 70.7 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FAINT PF04385.15 EAN31524.1 - 2e-16 59.8 25.2 4.5e-08 33.0 0.3 4.8 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Abhydrolase_2 PF02230.16 EAN31524.1 - 6.1e-07 29.5 0.6 0.0078 16.0 0.1 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EAN31524.1 - 1.1e-05 25.3 0.2 0.0054 16.4 0.1 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAN31524.1 - 0.0018 18.9 0.0 0.0026 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 EAN31524.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.13 EAN31524.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Zip PF02535.22 EAN31524.1 - 0.87 8.7 5.0 0.14 11.4 1.0 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter Peptidase_C48 PF02902.19 EAN31525.1 - 2e-32 112.8 0.7 2e-32 112.8 0.7 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain LupA PF18242.1 EAN31525.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain U1snRNP70_N PF12220.8 EAN31525.1 - 0.11 13.1 0.1 0.26 11.9 0.1 1.6 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AAA_2 PF07724.14 EAN31526.1 - 1.5e-54 184.6 0.1 2.7e-52 177.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EAN31526.1 - 1.1e-32 112.1 1.0 1.1e-32 112.1 1.0 3.6 3 1 2 5 5 3 1 AAA lid domain AAA PF00004.29 EAN31526.1 - 3.3e-25 89.0 0.0 1.2e-13 51.6 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EAN31526.1 - 6.4e-25 87.0 3.1 1.2e-24 86.2 0.3 3.1 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 EAN31526.1 - 1.7e-18 66.5 0.0 1.1e-09 38.3 0.0 2.7 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 EAN31526.1 - 3.1e-16 59.6 0.1 3.9e-11 43.1 0.0 3.6 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EAN31526.1 - 9.4e-11 41.7 0.0 2.8e-07 30.4 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 EAN31526.1 - 2.4e-10 41.1 0.1 0.00075 19.9 0.0 3.7 2 2 1 4 4 3 2 AAA ATPase domain AAA_14 PF13173.6 EAN31526.1 - 1.5e-07 31.5 3.4 0.016 15.3 0.0 4.3 3 3 0 3 3 3 2 AAA domain Torsin PF06309.11 EAN31526.1 - 2.6e-07 30.8 0.0 1.9e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Torsin RuvB_N PF05496.12 EAN31526.1 - 4e-07 29.9 1.6 0.27 11.0 0.0 4.5 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EAN31526.1 - 7.9e-07 29.7 2.4 0.19 12.3 0.0 4.7 4 0 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 EAN31526.1 - 8.8e-07 28.8 0.0 0.048 13.4 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EAN31526.1 - 4.5e-06 26.2 0.0 0.35 10.2 0.0 3.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EAN31526.1 - 6.3e-05 22.6 0.0 0.069 12.7 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region Roc PF08477.13 EAN31526.1 - 7.6e-05 22.9 0.0 0.28 11.4 0.0 3.0 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EAN31526.1 - 0.00037 20.9 1.4 0.82 10.1 0.0 3.6 4 0 0 4 4 3 1 RNA helicase Zeta_toxin PF06414.12 EAN31526.1 - 0.00082 18.7 0.0 0.15 11.3 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 EAN31526.1 - 0.00096 19.4 9.0 0.36 11.1 0.0 4.8 5 2 0 5 5 3 2 AAA domain ATPase_2 PF01637.18 EAN31526.1 - 0.0011 19.0 13.7 2.2 8.1 0.0 5.8 4 3 1 6 6 6 2 ATPase domain predominantly from Archaea TsaE PF02367.17 EAN31526.1 - 0.0013 18.7 0.0 1.2 9.2 0.0 2.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EAN31526.1 - 0.0014 18.6 0.0 0.74 9.7 0.0 2.9 2 1 0 2 2 2 1 NACHT domain ResIII PF04851.15 EAN31526.1 - 0.002 18.1 9.8 0.0066 16.5 0.0 5.0 4 1 1 5 5 5 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 EAN31526.1 - 0.0021 18.6 0.8 0.18 12.3 0.0 3.5 3 0 0 3 3 3 1 ABC transporter AAA_24 PF13479.6 EAN31526.1 - 0.0063 16.3 0.0 1 9.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta2 PF13177.6 EAN31526.1 - 0.0087 15.8 0.0 0.63 9.8 0.0 3.3 2 1 0 2 2 2 1 DNA polymerase III, delta subunit RsgA_GTPase PF03193.16 EAN31526.1 - 0.0089 15.9 4.9 3 7.7 0.0 3.9 3 3 1 4 4 3 2 RsgA GTPase AAA_33 PF13671.6 EAN31526.1 - 0.014 15.6 0.0 2.8 8.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EAN31526.1 - 0.046 13.3 0.1 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EAN31526.1 - 0.046 13.6 0.9 14 5.5 0.0 3.7 4 0 0 4 4 3 0 NTPase PduV-EutP PF10662.9 EAN31526.1 - 0.05 13.4 0.2 1 9.1 0.0 3.1 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EAN31526.1 - 0.052 13.8 0.0 18 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EAN31526.1 - 0.1 12.9 0.0 4.7 7.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_3 PF07726.11 EAN31526.1 - 0.11 12.4 0.0 19 5.2 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) betaPIX_CC PF16523.5 EAN31526.1 - 0.29 11.0 7.0 0.044 13.6 2.1 2.2 2 0 0 2 2 1 0 betaPIX coiled coil DUF16 PF01519.16 EAN31526.1 - 7.2 7.2 12.1 0.55 10.7 3.0 3.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 AP2 PF00847.20 EAN31527.1 - 3.1e-15 56.1 0.0 6.3e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 AP2 domain Ank_4 PF13637.6 EAN31527.1 - 0.15 12.7 0.2 0.67 10.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Glutaredoxin PF00462.24 EAN31528.1 - 3.3e-15 56.1 0.2 1.7e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin DUF3258 PF11646.8 EAN31528.1 - 0.022 14.9 0.3 0.034 14.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF3258 DUF562 PF04763.12 EAN31528.1 - 0.09 12.2 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF562) Ribosomal_L7Ae PF01248.26 EAN31529.1 - 1.6e-16 59.8 0.1 2.8e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family E1_4HB PF16191.5 EAN31529.1 - 0.089 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle YrhC PF14143.6 EAN31530.1 - 0.47 10.6 6.2 0.18 11.9 0.3 3.4 3 0 0 3 3 3 0 YrhC-like protein TMEM154 PF15102.6 EAN31530.1 - 1.8 8.5 4.6 0.57 10.1 0.4 2.1 2 0 0 2 2 2 0 TMEM154 protein family Ran_BP1 PF00638.18 EAN31531.1 - 4.1e-37 127.2 1.2 4.1e-37 127.2 1.2 2.3 2 1 1 3 3 3 1 RanBP1 domain Apolipoprotein PF01442.18 EAN31531.1 - 4e-05 23.6 0.6 8.8e-05 22.5 0.6 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EAN31531.1 - 0.13 12.9 2.6 2.2 8.9 0.7 3.1 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) Synaptobrevin PF00957.21 EAN31531.1 - 0.17 11.7 1.2 5.3 6.9 0.0 3.3 3 0 0 3 3 3 0 Synaptobrevin Tape_meas_lam_C PF09718.10 EAN31531.1 - 0.29 11.3 4.1 6.9 6.9 0.9 3.5 2 1 2 4 4 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phasin_2 PF09361.10 EAN31531.1 - 0.4 11.0 8.2 0.12 12.7 1.3 3.1 3 1 1 4 4 4 0 Phasin protein DUF2884 PF11101.8 EAN31531.1 - 0.42 10.1 12.1 4.5 6.7 12.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) YtxH PF12732.7 EAN31531.1 - 0.44 11.1 20.8 6.1 7.5 7.4 4.4 2 1 1 3 3 3 0 YtxH-like protein Fib_alpha PF08702.10 EAN31531.1 - 0.78 9.9 11.0 2.6 8.2 2.2 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 EAN31531.1 - 1.1 7.1 8.3 3.9 5.3 8.1 1.8 1 1 0 1 1 1 0 Prominin Ntox50 PF15542.6 EAN31531.1 - 1.9 9.3 5.8 0.61 10.9 0.5 2.5 1 1 0 2 2 2 0 Bacterial toxin 50 Dak2 PF02734.17 EAN31531.1 - 2.4 8.0 9.2 2.7 7.9 1.5 2.4 1 1 0 2 2 2 0 DAK2 domain Phasin PF05597.11 EAN31531.1 - 2.7 8.0 10.9 0.97 9.4 3.1 2.5 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Laminin_II PF06009.12 EAN31531.1 - 7.4 6.6 14.5 8 6.5 2.8 2.8 1 1 0 2 2 2 0 Laminin Domain II DUF948 PF06103.11 EAN31531.1 - 9 6.6 20.7 25 5.2 2.2 3.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 EAN31532.1 - 0.0036 17.9 1.4 0.0064 17.1 1.1 1.5 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) DUF745 PF05335.13 EAN31532.1 - 0.019 14.7 3.5 0.022 14.5 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Apo-CIII PF05778.12 EAN31532.1 - 0.032 13.9 0.7 0.058 13.0 0.6 1.5 1 1 1 2 2 2 0 Apolipoprotein CIII (Apo-CIII) HrpB_C PF08482.10 EAN31532.1 - 0.032 14.6 0.5 0.056 13.8 0.3 1.4 1 1 0 1 1 1 0 ATP-dependent helicase C-terminal Herpes_IE1 PF07340.11 EAN31532.1 - 0.047 12.6 0.9 0.046 12.6 0.9 1.0 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein Tape_meas_lam_C PF09718.10 EAN31532.1 - 0.054 13.6 0.9 9 6.5 0.1 2.2 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) RecG_N PF17190.4 EAN31532.1 - 0.11 13.3 3.9 0.27 12.0 3.8 1.7 1 1 0 1 1 1 0 RecG N-terminal helical domain Arm-DNA-bind_2 PF12167.8 EAN31532.1 - 0.11 12.4 0.5 0.23 11.4 0.1 1.7 2 0 0 2 2 2 0 Arm DNA-binding domain RNase_J_C PF17770.1 EAN31532.1 - 0.28 12.3 3.4 1 10.5 3.4 1.8 1 1 0 1 1 1 0 Ribonuclease J C-terminal domain DUF4446 PF14584.6 EAN31532.1 - 0.31 11.0 4.5 0.35 10.8 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) YtxH PF12732.7 EAN31532.1 - 0.56 10.8 10.0 1.4 9.5 5.4 2.1 1 1 1 2 2 2 0 YtxH-like protein DUF948 PF06103.11 EAN31532.1 - 2 8.7 6.8 22 5.4 6.8 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MMS1_N PF10433.9 EAN31534.1 - 1.3e-142 475.9 0.3 2.5e-142 475.0 0.3 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EAN31534.1 - 1.9e-79 267.3 0.5 6e-79 265.7 0.4 1.9 2 0 0 2 2 2 1 CPSF A subunit region CPW_WPC PF09717.10 EAN31535.1 - 2.5e-55 185.3 74.5 6e-15 56.0 4.7 7.8 8 0 0 8 8 8 7 Plasmodium falciparum domain of unknown function (CPW_WPC) Pro-kuma_activ PF09286.11 EAN31536.1 - 0.077 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain CTP_transf_like PF01467.26 EAN31539.1 - 6.4e-39 133.4 0.0 2.9e-18 66.4 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 EAN31539.1 - 0.0042 17.0 1.6 1.3 8.9 0.1 3.5 3 1 0 3 3 3 2 FAD synthetase HIGH_NTase1 PF05636.11 EAN31539.1 - 0.0065 15.7 0.0 0.89 8.7 0.0 2.3 2 0 0 2 2 2 2 HIGH Nucleotidyl Transferase FAINT PF04385.15 EAN31540.1 - 0.0036 17.3 0.3 0.0067 16.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function, DUF529 DUF523 PF04463.12 EAN31540.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF523) CENP-Q PF13094.6 EAN31541.1 - 0.0032 17.7 0.2 0.0044 17.2 0.2 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit YcbB PF08664.10 EAN31541.1 - 0.038 14.0 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 YcbB domain Nbl1_Borealin_N PF10444.9 EAN31541.1 - 0.094 12.4 0.6 0.48 10.1 0.2 2.1 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal Tweety PF04906.13 EAN31541.1 - 0.13 11.0 0.0 0.15 10.7 0.0 1.0 1 0 0 1 1 1 0 Tweety APOC4 PF15119.6 EAN31541.1 - 0.14 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein C4 FAINT PF04385.15 EAN31542.1 - 0.011 15.8 1.6 0.013 15.5 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Glyco_H_20C_C PF18088.1 EAN31543.1 - 0.14 12.0 1.3 2 8.3 0.7 2.6 2 1 1 3 3 3 0 Glycoside Hydrolase 20C C-terminal domain FAINT PF04385.15 EAN31543.1 - 0.16 12.1 6.4 0.35 10.9 6.4 1.7 1 0 0 1 1 1 0 Domain of unknown function, DUF529 FAST_1 PF06743.15 EAN31544.1 - 0.018 15.0 0.3 1.4 9.0 0.1 2.1 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 DUF1421 PF07223.11 EAN31544.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) SF-assemblin PF06705.11 EAN31545.1 - 9.5e-39 133.2 27.2 1.4e-38 132.7 27.2 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin Nup54 PF13874.6 EAN31545.1 - 0.0098 16.0 7.0 0.0098 16.0 7.0 2.5 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 tRNA-synt_2c PF01411.19 EAN31545.1 - 0.012 14.2 0.7 0.012 14.2 0.7 2.2 1 1 1 2 2 2 0 tRNA synthetases class II (A) Allexi_40kDa PF05549.11 EAN31545.1 - 0.17 11.4 14.7 0.29 10.6 4.4 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein Baculo_PEP_C PF04513.12 EAN31545.1 - 0.19 11.7 18.1 0.65 10.0 7.5 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EAN31545.1 - 0.29 10.5 10.3 1.2 8.4 10.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF885 PF05960.11 EAN31545.1 - 0.31 10.6 3.9 0.51 9.9 0.6 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) DUF5601 PF18151.1 EAN31545.1 - 0.93 9.8 7.3 2.5 8.5 1.3 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5601) Erp_C PF06780.11 EAN31545.1 - 1.1 9.3 14.0 1.5 8.9 4.6 2.7 1 1 1 2 2 2 0 Erp protein C-terminus NPV_P10 PF05531.12 EAN31545.1 - 1.3 9.6 13.6 0.3 11.6 2.8 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4600 PF15372.6 EAN31545.1 - 1.5 9.3 23.0 0.92 9.9 0.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) OGG_N PF07934.12 EAN31545.1 - 2 8.6 7.7 1.6 8.8 5.4 2.0 1 1 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain LPP PF04728.13 EAN31545.1 - 2.8 8.4 7.4 1.5 9.3 0.5 3.4 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF148 PF02520.17 EAN31545.1 - 2.9 8.0 19.6 1.1 9.4 6.4 3.7 1 1 3 4 4 4 0 Domain of unknown function DUF148 DUF1870 PF08965.10 EAN31545.1 - 3.3 7.8 7.9 0.61 10.1 0.6 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF1870) Cor1 PF04803.12 EAN31545.1 - 4 7.7 24.9 1.6 8.9 6.7 3.4 1 1 2 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF1664 PF07889.12 EAN31545.1 - 5.5 7.1 16.8 8.6 6.4 4.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HLH PF00010.26 EAN31545.1 - 7.7 6.6 10.5 4.9 7.2 1.9 2.9 3 0 0 3 3 3 0 Helix-loop-helix DNA-binding domain WD40 PF00400.32 EAN31546.1 - 1.5e-23 82.6 13.7 0.00083 20.1 0.1 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN31546.1 - 0.00026 21.2 0.5 2.2 8.6 0.0 4.8 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain NAP PF00956.18 EAN31547.1 - 6.1e-27 94.5 1.4 9e-27 93.9 1.4 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) WD40 PF00400.32 EAN31548.1 - 7.6e-06 26.6 6.8 0.11 13.4 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EAN31548.1 - 0.055 12.4 0.4 4.8 6.1 0.0 2.9 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein U3snoRNP10 PF12397.8 EAN31549.1 - 0.053 13.9 0.9 0.48 10.8 0.9 2.0 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 Methyltransf_31 PF13847.6 EAN31550.1 - 1e-10 41.6 0.1 1.3e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAN31550.1 - 1.1e-09 38.8 0.0 1.6e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAN31550.1 - 1.2e-08 35.5 0.0 1.6e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAN31550.1 - 1.7e-08 35.1 0.1 2.8e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAN31550.1 - 2e-05 24.5 0.0 2.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAN31550.1 - 0.015 14.7 0.0 0.035 13.5 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.18 EAN31550.1 - 0.052 13.0 0.1 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain MetW PF07021.12 EAN31550.1 - 0.075 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 EAN31550.1 - 0.091 12.3 0.0 0.26 10.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 EAN31550.1 - 0.16 11.2 0.0 0.46 9.7 0.0 1.6 1 1 1 2 2 2 0 O-methyltransferase domain Extensin_2 PF04554.13 EAN31551.1 - 0.6 10.2 15.2 1.3 9.2 15.2 1.5 1 0 0 1 1 1 0 Extensin-like region DUF5489 PF17592.2 EAN31552.1 - 0.047 14.2 2.6 1.5 9.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5489) DUF2272 PF10030.9 EAN31552.1 - 0.22 11.2 0.1 0.47 10.2 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) HlyIII PF03006.20 EAN31553.1 - 4.9e-26 91.8 21.5 6.4e-26 91.5 21.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.20 EAN31554.1 - 1.1e-21 77.6 17.5 1.3e-21 77.4 17.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related Arm_3 PF16186.5 EAN31555.1 - 0.02 14.4 0.0 0.045 13.3 0.0 1.6 1 1 0 1 1 1 0 Atypical Arm repeat V-ATPase_H_C PF11698.8 EAN31556.1 - 0.00053 20.1 1.3 0.25 11.5 0.1 2.9 2 0 0 2 2 2 2 V-ATPase subunit H RICTOR_V PF14668.6 EAN31556.1 - 0.056 13.7 0.3 15 5.9 0.1 3.4 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.6 EAN31556.1 - 0.11 13.0 0.2 2.1 8.8 0.1 2.5 2 0 0 2 2 2 0 HEAT repeats DUF2019 PF09450.10 EAN31556.1 - 0.12 12.3 0.0 4.9 7.2 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2019) Arm PF00514.23 EAN31556.1 - 0.29 11.2 10.8 6 7.1 0.0 5.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Steroid_dh PF02544.16 EAN31560.1 - 5.5e-11 42.7 0.8 6.1e-11 42.5 0.8 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase LCCL PF03815.19 EAN31561.1 - 4.2e-18 65.3 0.3 4.2e-18 65.3 0.3 3.2 3 0 0 3 3 3 1 LCCL domain F5_F8_type_C PF00754.25 EAN31561.1 - 5.2e-08 33.1 0.2 1.5e-07 31.6 0.2 1.8 1 0 0 1 1 1 1 F5/8 type C domain Ricin_B_lectin PF00652.22 EAN31561.1 - 1.7e-07 31.5 10.3 0.00011 22.5 0.1 3.9 3 1 1 4 4 4 2 Ricin-type beta-trefoil lectin domain Spore_coat_CotO PF14153.6 EAN31561.1 - 0.36 10.7 19.1 0.69 9.8 19.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO TCTP PF00838.17 EAN31562.1 - 0.051 13.9 0.3 0.051 13.9 0.3 2.0 2 0 0 2 2 2 0 Translationally controlled tumour protein FadA PF09403.10 EAN31562.1 - 0.2 12.1 9.2 0.043 14.3 3.4 2.7 3 0 0 3 3 3 0 Adhesion protein FadA SKA2 PF16740.5 EAN31562.1 - 0.31 10.8 4.3 1.3 8.8 4.3 2.1 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 C2 PF00168.30 EAN31563.1 - 0.001 19.3 0.6 3.3 8.1 0.1 4.0 4 0 0 4 4 4 2 C2 domain Ferlin_C PF16165.5 EAN31564.1 - 0.0011 19.0 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Ferlin C-terminus C2 PF00168.30 EAN31564.1 - 0.0024 18.1 0.0 0.0048 17.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain Adaptin_N PF01602.20 EAN31565.1 - 3e-74 250.5 20.8 1.4e-71 241.7 16.6 2.2 2 0 0 2 2 2 2 Adaptin N terminal region Telomere_reg-2 PF10193.9 EAN31565.1 - 0.072 13.5 1.5 0.52 10.8 0.1 3.2 3 0 0 3 3 3 0 Telomere length regulation protein STAG PF08514.11 EAN31566.1 - 1.7e-05 24.7 0.1 1.7e-05 24.7 0.1 3.9 6 0 0 6 6 6 1 STAG domain TFIIF_alpha PF05793.12 EAN31566.1 - 0.019 13.6 6.7 0.04 12.5 6.7 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2666 PF10869.8 EAN31566.1 - 0.077 13.2 4.7 5.5 7.2 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2666) Ku_PK_bind PF08785.11 EAN31566.1 - 0.097 12.8 5.9 0.19 11.9 0.1 4.0 4 1 0 4 4 4 0 Ku C terminal domain like Ribosomal_L28 PF00830.19 EAN31567.1 - 0.15 12.2 0.3 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 Ribosomal L28 family H_PPase PF03030.16 EAN31568.1 - 1.1e-12 47.5 37.8 9.9e-07 27.8 6.6 3.5 3 1 0 3 3 3 3 Inorganic H+ pyrophosphatase Uds1 PF15456.6 EAN31568.1 - 5.6 7.1 8.9 1.2 9.3 3.8 2.3 2 0 0 2 2 2 0 Up-regulated During Septation Thioredoxin PF00085.20 EAN31569.1 - 3.7e-28 97.5 0.0 4.1e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAN31569.1 - 2.2e-08 34.3 0.2 1.7e-05 25.1 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin-like Phosducin PF02114.16 EAN31569.1 - 5.5e-06 25.5 0.0 6.2e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin_2 PF13098.6 EAN31569.1 - 1.1e-05 25.8 0.2 0.00011 22.7 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EAN31569.1 - 0.00016 21.2 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EAN31569.1 - 0.00019 21.4 0.1 0.00039 20.3 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EAN31569.1 - 0.00031 20.5 0.0 0.00036 20.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EAN31569.1 - 0.0031 17.2 0.0 0.016 14.9 0.0 1.8 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 EAN31569.1 - 0.019 15.2 0.1 0.024 14.8 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 EAN31569.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain HEAT_EZ PF13513.6 EAN31570.1 - 6.6e-09 36.1 0.0 2.9e-06 27.7 0.0 3.9 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 EAN31570.1 - 9.3e-07 28.6 4.8 1.6 9.2 0.0 7.4 9 0 0 9 9 9 2 HEAT repeat IBN_N PF03810.19 EAN31570.1 - 2.1e-06 27.6 1.2 2.1e-06 27.6 1.2 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain TAF6_C PF07571.13 EAN31570.1 - 0.018 15.3 0.1 0.25 11.7 0.0 3.1 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 EAN31570.1 - 0.025 15.2 0.3 3.2 8.4 0.0 4.1 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EAN31570.1 - 0.2 12.1 0.0 4 7.9 0.0 3.1 3 1 1 4 4 4 0 HEAT repeats AMP-binding PF00501.28 EAN31571.1 - 4.1e-88 295.8 0.0 4.9e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EAN31571.1 - 6.2e-20 70.9 2.7 1e-19 70.1 1.2 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EAN31571.1 - 4.6e-17 62.8 0.0 1.4e-16 61.2 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain zf-CCCH_2 PF14608.6 EAN31572.1 - 1.7e-10 40.9 20.5 2.5e-05 24.6 4.1 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EAN31572.1 - 2.4e-06 27.2 11.3 0.0063 16.3 2.3 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EAN31572.1 - 0.036 14.1 0.8 0.036 14.1 0.8 2.9 3 0 0 3 3 3 0 Zinc finger domain Fes1 PF08609.10 EAN31572.1 - 0.11 13.4 9.0 0.1 13.5 6.4 2.3 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 zf-CCCH PF00642.24 EAN31572.1 - 0.17 11.8 10.1 0.37 10.7 1.5 2.7 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) START PF01852.19 EAN31574.1 - 0.0066 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 START domain SPOUT_MTase PF02590.17 EAN31575.1 - 0.16 11.9 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Astro_capsid_p PF12226.8 EAN31576.1 - 0.21 10.7 4.7 0.36 9.9 4.7 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Mago_nashi PF02792.14 EAN31577.1 - 1e-69 233.1 1.5 1.2e-69 233.0 1.5 1.0 1 0 0 1 1 1 1 Mago nashi protein Bromodomain PF00439.25 EAN31579.1 - 1.9e-17 63.1 0.5 6.5e-17 61.4 0.1 2.2 2 0 0 2 2 2 1 Bromodomain MS_channel PF00924.18 EAN31580.1 - 1.4e-16 60.6 1.6 1.4e-16 60.6 1.6 1.9 2 0 0 2 2 2 1 Mechanosensitive ion channel Pescadillo_N PF06732.11 EAN31581.1 - 7.3e-80 268.4 0.0 1.3e-79 267.6 0.0 1.3 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 EAN31581.1 - 6.8e-08 32.8 0.0 1.7e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain ACDC PF14733.6 EAN31581.1 - 0.17 12.2 0.3 18 5.8 0.1 3.4 4 0 0 4 4 4 0 AP2-coincident C-terminal Rad51 PF08423.11 EAN31582.1 - 7.2e-116 385.9 0.0 1.2e-115 385.2 0.0 1.3 2 0 0 2 2 2 1 Rad51 RecA PF00154.21 EAN31582.1 - 2.4e-08 33.8 0.0 3.5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EAN31582.1 - 3.2e-07 30.1 0.0 5.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EAN31582.1 - 7.9e-05 22.1 0.6 0.00039 19.8 0.6 2.1 1 1 0 1 1 1 1 KaiC MS_channel PF00924.18 EAN31583.1 - 6.2e-11 42.2 5.2 1.6e-10 40.9 5.2 1.8 1 0 0 1 1 1 1 Mechanosensitive ion channel RPW8 PF05659.11 EAN31583.1 - 0.34 10.6 1.3 3.3 7.4 0.1 2.5 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Med26 PF08711.11 EAN31585.1 - 7.3e-07 29.1 0.3 7.9e-06 25.8 0.0 2.4 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Syntaxin PF00804.25 EAN31585.1 - 0.021 14.5 0.2 0.054 13.2 0.2 1.6 1 0 0 1 1 1 0 Syntaxin Nucleoporin_FG PF13634.6 EAN31586.1 - 2.7e-23 82.6 115.1 1.1e-07 32.6 28.2 4.8 1 1 3 4 4 4 4 Nucleoporin FG repeat region DnaJ PF00226.31 EAN31587.1 - 7.5e-17 61.2 2.7 7.5e-17 61.2 2.7 2.0 2 0 0 2 2 2 1 DnaJ domain PSD5 PF07637.11 EAN31587.1 - 0.014 15.7 0.1 0.96 9.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) Myb_DNA-bind_3 PF12776.7 EAN31587.1 - 0.3 12.1 4.6 3.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain MitMem_reg PF13012.6 EAN31588.1 - 9.6e-27 93.6 0.3 1.4e-26 93.1 0.3 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EAN31588.1 - 4.7e-26 91.1 0.1 1.3e-25 89.7 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2423 PF10338.9 EAN31589.1 - 0.00083 19.5 0.1 0.0022 18.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Ribosomal_L36e PF01158.18 EAN31590.1 - 9.1e-36 122.0 0.8 1.1e-35 121.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e Bystin PF05291.11 EAN31591.1 - 3.8e-95 318.5 0.3 3.8e-95 318.5 0.3 1.4 2 0 0 2 2 2 1 Bystin MIF4G PF02854.19 EAN31593.1 - 1.2e-25 90.4 3.5 5.6e-25 88.2 3.5 2.1 1 1 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EAN31593.1 - 0.0081 16.1 2.1 0.011 15.7 0.6 2.0 2 0 0 2 2 2 1 MA3 domain RF-1 PF00472.20 EAN31594.1 - 4.8e-29 100.6 1.5 7.5e-29 100.0 1.5 1.2 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.18 EAN31594.1 - 1.9e-23 83.4 0.0 2.1e-22 79.9 0.0 2.3 2 1 0 2 2 2 1 PCRF domain DUF4227 PF14004.6 EAN31594.1 - 0.11 12.5 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) Acid_PPase PF12689.7 EAN31595.1 - 8.3e-05 22.5 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Acid Phosphatase 5_nucleotid PF05761.14 EAN31595.1 - 0.085 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family zf-primase PF09329.11 EAN31596.1 - 7.9e-08 32.0 0.4 7.9e-08 32.0 0.4 2.0 2 0 0 2 2 2 1 Primase zinc finger zf-C3Hc3H PF13891.6 EAN31596.1 - 0.11 12.8 0.3 0.35 11.3 0.3 1.8 1 0 0 1 1 1 0 Potential DNA-binding domain CHDCT2 PF08074.11 EAN31596.1 - 3 8.0 8.0 0.45 10.7 3.3 2.0 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain DUF4400 PF14348.6 EAN31597.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) FAINT PF04385.15 EAN31598.1 - 4.6e-24 84.3 24.5 1.7e-07 31.2 2.0 6.5 6 0 0 6 6 6 5 Domain of unknown function, DUF529 TPK_B1_binding PF04265.14 EAN31598.1 - 0.019 14.7 0.0 0.072 12.8 0.0 2.0 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain FAINT PF04385.15 EAN31599.1 - 0.00043 20.3 12.9 0.015 15.3 0.3 4.6 4 1 0 4 4 4 2 Domain of unknown function, DUF529 NUC153 PF08159.12 EAN31600.1 - 0.0085 15.9 0.4 0.017 14.9 0.4 1.5 1 0 0 1 1 1 1 NUC153 domain RabGAP-TBC PF00566.18 EAN31601.1 - 4.4e-14 52.7 6.2 5.7e-13 49.0 6.2 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF1729 PF08354.10 EAN31601.1 - 0.0033 16.4 0.2 0.0041 16.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) DUF4618 PF15397.6 EAN31601.1 - 0.11 11.9 2.6 0.12 11.7 0.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) RabGAP-TBC PF00566.18 EAN31602.1 - 2.3e-08 34.0 0.8 4.6e-08 33.0 0.8 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sec1 PF00995.23 EAN31603.1 - 3.4e-94 317.1 9.5 4.4e-94 316.8 9.5 1.0 1 0 0 1 1 1 1 Sec1 family EF_TS PF00889.19 EAN31605.1 - 1.7e-20 73.6 0.1 1.6e-09 37.7 0.3 2.4 2 0 0 2 2 2 2 Elongation factor TS HOIP-UBA PF16678.5 EAN31605.1 - 0.0069 16.4 0.1 0.017 15.1 0.1 1.6 1 0 0 1 1 1 1 HOIP UBA domain pair Thioredoxin PF00085.20 EAN31606.1 - 0.00055 19.9 0.0 0.0009 19.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Sushi PF00084.20 EAN31607.1 - 0.084 13.5 0.4 0.97 10.1 0.0 2.8 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) AMMECR1 PF01871.17 EAN31609.1 - 2.1e-46 157.6 0.0 2.4e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 EcoRII-N PF09217.10 EAN31609.1 - 0.065 13.0 0.3 0.37 10.5 0.0 2.2 3 0 0 3 3 3 0 Restriction endonuclease EcoRII, N-terminal zf-C3HC4_2 PF13923.6 EAN31609.1 - 0.26 11.2 1.3 2.5 8.0 1.3 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRN3 PF05327.11 EAN31610.1 - 1.1e-55 189.2 25.0 2.6e-53 181.4 22.8 3.5 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF3223 PF11523.8 EAN31610.1 - 1.3e-11 45.2 0.2 8.1e-11 42.6 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3223) Nab2 PF11517.8 EAN31610.1 - 0.062 13.6 1.7 3.9 7.8 0.0 3.4 3 1 1 4 4 4 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) NAF PF03822.14 EAN31611.1 - 0.0081 16.3 0.3 0.027 14.7 0.1 1.8 2 0 0 2 2 2 1 NAF domain NPV_P10 PF05531.12 EAN31612.1 - 0.091 13.2 0.4 1.2 9.7 0.3 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CAF1 PF04857.20 EAN31613.1 - 1.4e-39 136.2 1.6 2e-22 79.8 0.1 2.0 1 1 1 2 2 2 2 CAF1 family ribonuclease PUF PF00806.19 EAN31615.1 - 1.3e-49 163.1 5.3 5.1e-08 32.2 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat WD40 PF00400.32 EAN31616.1 - 3.8e-24 84.5 11.4 5.1e-05 24.0 1.6 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN31616.1 - 6.3e-08 32.8 1.2 0.017 15.4 0.1 4.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EAN31616.1 - 0.0011 18.9 3.1 0.062 13.2 0.4 2.5 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term LisH_TPL PF17814.1 EAN31616.1 - 0.0042 16.7 0.2 0.01 15.5 0.2 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain LisH PF08513.11 EAN31616.1 - 0.033 14.1 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 LisH Ge1_WD40 PF16529.5 EAN31616.1 - 0.035 13.1 0.0 0.55 9.1 0.0 2.4 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EAN31616.1 - 0.065 12.6 1.0 5.7 6.2 0.0 3.2 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal DEAD PF00270.29 EAN31617.1 - 6.4e-48 162.8 0.0 1.2e-45 155.4 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN31617.1 - 5.5e-27 94.3 0.1 5.5e-27 94.3 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN31617.1 - 4.3e-05 23.6 0.0 0.00052 20.1 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Presenilin PF01080.17 EAN31617.1 - 1.5 7.5 8.5 2.5 6.8 8.5 1.3 1 0 0 1 1 1 0 Presenilin Ribosomal_S24e PF01282.19 EAN31618.1 - 1.5e-30 104.9 0.0 1.5e-30 104.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S24e DUF4051 PF13260.6 EAN31618.1 - 0.082 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) SAP30_Sin3_bdg PF13867.6 EAN31618.1 - 0.12 12.7 0.8 0.5 10.7 0.1 2.1 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 UbiA PF01040.18 EAN31619.1 - 4.9e-40 137.4 9.6 6.7e-40 137.0 9.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family eIF2A PF08662.11 EAN31620.1 - 2.8e-28 99.1 0.2 1.3e-22 80.7 0.9 4.2 3 2 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A MciZ PF13072.6 EAN31620.1 - 0.17 11.7 1.0 0.41 10.5 1.0 1.5 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ p25-alpha PF05517.12 EAN31621.1 - 2.3e-10 40.8 0.0 3e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 p25-alpha DCX PF03607.17 EAN31621.1 - 4.6e-07 29.9 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Doublecortin AP2 PF00847.20 EAN31622.1 - 2.4e-16 59.7 0.4 1.5e-09 38.0 0.0 2.4 2 0 0 2 2 2 2 AP2 domain zf-NOSIP PF15906.5 EAN31623.1 - 8.2e-05 22.7 0.2 0.0005 20.1 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_4 PF15227.6 EAN31623.1 - 0.0028 17.8 0.5 0.0078 16.3 0.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAN31623.1 - 0.0028 17.6 0.2 0.012 15.7 0.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAN31623.1 - 0.0083 16.0 0.3 0.017 15.0 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAN31623.1 - 0.0088 15.9 0.6 0.018 14.9 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAN31623.1 - 0.11 12.4 0.5 0.25 11.2 0.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 EAN31624.1 - 2.1e-16 59.8 16.4 3e-10 40.1 8.1 2.4 2 0 0 2 2 2 2 B-box zinc finger PARP PF00644.20 EAN31624.1 - 0.0059 16.2 0.0 0.021 14.5 0.0 2.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain IBR PF01485.21 EAN31624.1 - 0.55 10.5 10.3 2.5 8.4 0.7 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain PROCN PF08083.11 EAN31625.1 - 0.34 9.6 0.4 0.5 9.0 0.4 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain BolA PF01722.18 EAN31626.1 - 3.9e-19 68.7 0.0 9.9e-19 67.4 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein AF-4 PF05110.13 EAN31628.1 - 0.046 11.8 7.5 0.065 11.3 7.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF645 PF04875.12 EAN31628.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF645 DUF4692 PF15763.5 EAN31628.1 - 3.5 8.1 6.5 3.6 8.0 4.7 1.9 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Ribosomal_S11 PF00411.19 EAN31629.1 - 1.4e-46 157.5 1.1 1.9e-46 157.0 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.9 EAN31629.1 - 0.08 12.0 0.1 0.089 11.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) IF-2 PF11987.8 EAN31630.1 - 0.00045 20.3 0.1 0.00094 19.3 0.1 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 Pyr_redox PF00070.27 EAN31631.1 - 0.0083 16.7 0.1 0.021 15.4 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Yop-YscD_ppl PF16693.5 EAN31631.1 - 0.028 13.8 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain IF-2 PF11987.8 EAN31631.1 - 0.062 13.4 0.7 0.11 12.7 0.7 1.4 1 0 0 1 1 1 0 Translation-initiation factor 2 hSH3 PF14603.6 EAN31631.1 - 0.082 13.3 0.4 0.31 11.5 0.1 2.2 2 0 0 2 2 2 0 Helically-extended SH3 domain ELK PF03789.13 EAN31631.1 - 0.11 12.7 0.6 0.21 11.7 0.6 1.5 1 0 0 1 1 1 0 ELK domain DUF3776 PF12618.8 EAN31631.1 - 0.19 12.3 0.3 0.35 11.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) GTP_EFTU PF00009.27 EAN31632.1 - 1.7e-09 37.5 0.1 1.9e-08 34.1 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EAN31632.1 - 2.5e-07 30.8 2.5 2.9e-07 30.5 1.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EAN31632.1 - 4.1e-06 26.8 0.0 1.5e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EAN31632.1 - 4.9e-05 23.1 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D2 PF03144.25 EAN31632.1 - 0.015 15.7 0.1 5.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Dynamin_N PF00350.23 EAN31632.1 - 0.019 15.0 7.3 0.69 9.9 0.1 3.6 2 1 1 3 3 3 0 Dynamin family hSH3 PF14603.6 EAN31632.1 - 0.027 14.9 0.3 0.098 13.1 0.1 2.1 2 0 0 2 2 2 0 Helically-extended SH3 domain cpYpsA PF12694.7 EAN31632.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family Pyr_redox PF00070.27 EAN31632.1 - 0.065 13.8 0.7 0.2 12.3 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L11_N PF03946.14 EAN31634.1 - 1.3e-22 79.4 0.2 1.9e-22 78.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EAN31634.1 - 2.4e-14 53.6 0.2 4.1e-14 52.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Peptidase_A8 PF01252.18 EAN31635.1 - 0.017 15.4 1.3 0.025 14.8 1.3 1.2 1 0 0 1 1 1 0 Signal peptidase (SPase) II DUF2244 PF10003.9 EAN31635.1 - 1.3 8.7 4.6 1.8 8.2 4.6 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) FtsL PF04999.13 EAN31635.1 - 3.1 7.9 4.0 4 7.5 2.2 1.9 1 1 1 2 2 2 0 Cell division protein FtsL Phage_holin_3_6 PF07332.11 EAN31635.1 - 8.4 6.5 7.3 12 6.0 7.3 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III HTH_9 PF08221.11 EAN31636.1 - 6.7e-11 42.1 1.6 1.7e-09 37.6 0.1 3.1 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EAN31636.1 - 0.002 18.0 0.5 0.88 9.5 0.0 3.2 3 1 0 3 3 3 2 TFIIE alpha subunit ADPrib_exo_Tox PF03496.14 EAN31636.1 - 0.0058 16.0 3.4 0.072 12.4 1.0 2.5 1 1 1 2 2 2 2 ADP-ribosyltransferase exoenzyme WD40 PF00400.32 EAN31637.1 - 2.1e-60 199.3 26.8 1.1e-10 41.9 0.1 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN31637.1 - 2e-20 72.9 1.4 6.2e-05 23.2 0.0 5.9 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EAN31637.1 - 4.3e-05 23.9 0.4 9.7e-05 22.8 0.4 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EAN31637.1 - 5.6e-05 22.0 4.6 2.7 6.5 0.0 4.4 3 1 1 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EAN31637.1 - 0.00052 19.1 0.3 0.41 9.6 0.0 4.0 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Bac_RepA_C PF18008.1 EAN31637.1 - 0.0084 16.4 0.2 0.017 15.5 0.2 1.5 1 0 0 1 1 1 1 Replication initiator protein A C-terminal domain WD40_like PF17005.5 EAN31637.1 - 0.12 11.7 0.0 2 7.7 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain PD40 PF07676.12 EAN31637.1 - 0.13 12.3 4.4 2.2 8.3 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PDE4_UCR PF18100.1 EAN31638.1 - 0.035 14.8 0.6 0.089 13.4 0.6 1.7 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) RPAP1_C PF08620.10 EAN31639.1 - 3.6e-20 71.8 0.0 8e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EAN31639.1 - 0.00072 19.3 1.7 0.0011 18.6 0.1 2.2 2 0 0 2 2 2 1 RPAP1-like, N-terminal WD40 PF00400.32 EAN31640.1 - 5.1e-52 172.7 29.4 8.6e-11 42.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN31640.1 - 3.4e-14 52.9 2.8 0.033 14.5 0.0 5.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAN31640.1 - 3.6e-07 29.8 0.0 0.00014 21.3 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 EAN31640.1 - 4.7e-06 25.8 0.1 0.75 8.7 0.0 4.2 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EAN31640.1 - 0.0017 17.0 0.1 2.6 6.5 0.0 3.6 1 1 4 5 5 5 1 Cytochrome D1 heme domain SGL PF08450.12 EAN31640.1 - 0.0036 16.9 0.2 0.23 11.0 0.0 2.9 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 EAN31640.1 - 0.0064 16.4 1.1 5.3 7.1 0.1 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 EAN31640.1 - 0.008 16.6 1.1 0.15 12.5 0.0 3.2 3 0 0 3 3 3 1 PQQ-like domain Nup160 PF11715.8 EAN31640.1 - 0.018 13.7 8.9 1.9 7.0 0.1 4.2 2 1 2 5 5 5 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EAN31640.1 - 0.031 13.2 3.5 0.35 9.8 0.2 3.0 2 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Proteasome_A_N PF10584.9 EAN31640.1 - 0.12 12.0 1.7 11 5.8 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature LRR_4 PF12799.7 EAN31641.1 - 1.4e-20 73.1 25.6 2.1e-05 24.8 4.3 6.0 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAN31641.1 - 2.2e-14 53.0 20.2 8.6e-05 22.2 0.0 5.5 4 1 1 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 EAN31641.1 - 7.3e-13 48.4 11.3 0.00036 20.1 0.1 4.5 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 EAN31641.1 - 0.0006 20.0 14.8 1.1 10.1 0.0 6.4 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 EAN31641.1 - 8.1 6.8 21.0 10 6.5 0.0 6.4 7 1 1 8 8 8 0 Leucine Rich repeat SpoU_methylase PF00588.19 EAN31642.1 - 0.00013 22.2 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family PCI PF01399.27 EAN31644.1 - 9.1e-12 45.4 0.4 4.8e-11 43.1 0.1 2.4 2 1 0 2 2 2 1 PCI domain Peptidase_M22 PF00814.25 EAN31645.1 - 1.4e-75 254.5 0.0 1.7e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Myb_DNA-bind_6 PF13921.6 EAN31646.1 - 0.0033 17.6 0.2 0.029 14.6 0.1 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain NES_C_h PF18208.1 EAN31646.1 - 0.04 14.2 2.5 0.093 13.0 0.3 2.4 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain Dynamin_M PF01031.20 EAN31647.1 - 2e-77 260.3 0.1 2e-77 260.3 0.1 2.3 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 EAN31647.1 - 1.3e-45 155.5 1.8 3.1e-45 154.3 0.0 2.5 3 1 0 3 3 3 1 Dynamin family GED PF02212.18 EAN31647.1 - 3.8e-23 81.5 0.3 1e-22 80.1 0.3 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EAN31647.1 - 0.0003 20.8 0.1 0.0013 18.8 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase YwqJ-deaminase PF14431.6 EAN31647.1 - 0.041 14.1 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 YwqJ-like deaminase Adaptin_N PF01602.20 EAN31649.1 - 6.2e-64 216.4 9.5 1.1e-63 215.6 9.5 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_g_Cpla PF16381.5 EAN31649.1 - 2.2e-24 85.8 0.7 1.9e-23 82.8 0.2 2.5 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform COP-gamma_platf PF08752.10 EAN31649.1 - 9e-17 61.6 5.3 1.4e-16 61.0 3.9 2.1 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.6 EAN31649.1 - 3.1e-11 43.5 0.0 0.0018 18.6 0.0 5.4 3 1 1 5 5 5 1 HEAT repeats Cnd1 PF12717.7 EAN31649.1 - 1.8e-07 31.3 9.7 1.9e-07 31.3 0.2 5.0 5 2 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAN31649.1 - 0.00014 21.8 0.0 6.7 7.3 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat Coatomer_b_Cpla PF14806.6 EAN31649.1 - 0.00031 20.7 0.3 0.00031 20.7 0.3 2.2 3 0 0 3 3 3 1 Coatomer beta subunit appendage platform Seryl_tRNA_N PF02403.22 EAN31649.1 - 0.014 15.6 0.3 0.042 14.1 0.3 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RIX1 PF08167.12 EAN31649.1 - 0.063 13.0 2.0 1 9.1 0.1 3.0 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis DUF5069 PF16798.5 EAN31650.1 - 0.076 13.2 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) Ca_bind_SSO6904 PF18249.1 EAN31650.1 - 0.11 12.9 0.9 5.1 7.5 0.2 2.2 2 0 0 2 2 2 0 Calcium binding protein SSO6904 DUF2894 PF11445.8 EAN31651.1 - 0.021 15.3 7.2 0.029 14.8 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DHHC PF01529.20 EAN31652.1 - 3.2e-35 121.2 16.4 3.2e-35 121.2 16.4 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Imm72 PF15584.6 EAN31652.1 - 0.028 14.5 0.2 1.5 9.0 0.0 3.0 2 1 1 3 3 3 0 Immunity protein 72 zf-CDGSH PF09360.10 EAN31653.1 - 1e-10 41.6 0.8 2.3e-10 40.5 0.8 1.6 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type CDC73_C PF05179.14 EAN31654.1 - 5e-42 143.3 2.2 1e-41 142.3 2.2 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal NUDIX PF00293.28 EAN31655.1 - 8.4e-18 64.7 0.0 9.9e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain VWA PF00092.28 EAN31657.1 - 1.1e-23 84.4 2.2 4e-22 79.3 0.0 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EAN31657.1 - 2.9e-12 47.2 0.0 8.8e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EAN31657.1 - 3.8e-05 23.7 0.0 0.00012 22.0 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 EAN31657.1 - 0.0092 16.1 0.0 0.0092 16.1 0.0 2.0 2 0 0 2 2 2 1 vWA found in TerF C terminus TSP_1 PF00090.19 EAN31657.1 - 0.062 13.5 0.4 0.25 11.6 0.4 2.0 1 0 0 1 1 1 0 Thrombospondin type 1 domain Stm1_N PF09598.10 EAN31657.1 - 0.97 10.3 0.0 0.97 10.3 0.0 4.3 4 2 0 4 4 4 0 Stm1 Mitofilin PF09731.9 EAN31657.1 - 5.8 5.6 43.8 2.9 6.6 12.1 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein VWA PF00092.28 EAN31658.1 - 2.1e-25 89.9 0.0 3.3e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EAN31658.1 - 5.5e-10 39.9 0.0 2e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 EAN31658.1 - 3.2e-05 23.9 0.0 0.00012 22.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain TSP_1 PF00090.19 EAN31658.1 - 0.00018 21.6 1.9 0.00018 21.6 1.9 2.5 2 0 0 2 2 2 1 Thrombospondin type 1 domain DUF4366 PF14283.6 EAN31658.1 - 0.02 15.0 0.2 0.045 13.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Copine PF07002.16 EAN31658.1 - 0.082 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Copine FoP_duplication PF13865.6 EAN31660.1 - 7.1e-19 68.1 6.2 7.1e-19 68.1 6.2 2.6 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 S4 PF01479.25 EAN31661.1 - 8.2e-09 35.0 0.7 1.8e-08 34.0 0.1 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EAN31661.1 - 1e-06 29.5 1.6 1.1e-05 26.3 0.6 2.3 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain SPT16 PF08644.11 EAN31663.1 - 2.9e-47 160.6 0.4 2.9e-47 160.6 0.4 2.8 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 EAN31663.1 - 5.4e-24 85.0 0.0 9.4e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EAN31663.1 - 1.3e-13 51.2 0.0 3.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like FACT-Spt16_Nlob PF14826.6 EAN31664.1 - 2.2e-19 69.9 0.0 2.5e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Ribosomal_S2 PF00318.20 EAN31664.1 - 0.12 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 RRM_1 PF00076.22 EAN31665.1 - 3e-30 103.8 0.0 1.4e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAN31665.1 - 0.0019 18.0 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EAN31665.1 - 0.025 14.7 0.0 0.086 13.0 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif DUF2890 PF11081.8 EAN31666.1 - 0.07 13.3 2.4 1 9.4 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) Proteasome PF00227.26 EAN31667.1 - 1.6e-34 119.1 0.1 1.9e-34 118.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 EAN31668.1 - 3.4e-29 102.3 1.6 3.4e-29 102.3 1.6 2.5 3 1 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 EAN31668.1 - 5.4e-12 45.6 0.4 5.4e-12 45.6 0.4 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain ATP-synt_C PF00137.21 EAN31669.1 - 2e-13 50.5 11.3 2e-13 50.5 11.3 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DDDD PF10161.9 EAN31669.1 - 0.5 10.2 1.5 1.1 9.1 0.1 2.1 1 1 1 2 2 2 0 Putative mitochondrial precursor protein PIRT PF15099.6 EAN31669.1 - 3.1 7.4 6.3 0.75 9.4 1.9 1.8 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family PWI PF01480.17 EAN31670.1 - 3.4e-12 46.5 0.2 8.4e-12 45.2 0.2 1.6 1 0 0 1 1 1 1 PWI domain AIM3 PF17096.5 EAN31671.1 - 2.1 9.3 5.2 5.9 7.9 5.2 1.7 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 PTH2 PF01981.16 EAN31672.1 - 9e-15 55.0 0.0 1e-14 54.8 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 ApoM PF11032.8 EAN31672.1 - 0.0091 15.7 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 ApoM domain Histone PF00125.24 EAN31673.1 - 9.6e-53 178.0 1.1 1.1e-52 177.9 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EAN31673.1 - 0.00012 22.4 0.0 0.00019 21.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EAN31673.1 - 0.0003 20.9 0.4 0.00047 20.2 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAN31673.1 - 0.00036 21.1 1.3 0.00043 20.9 1.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EAN31673.1 - 0.071 13.4 0.6 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EAN31673.1 - 0.098 12.7 0.2 0.17 11.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone_H2A_C PF16211.5 EAN31674.1 - 3.4e-17 61.9 0.1 6.7e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EAN31674.1 - 1.2e-14 54.8 0.0 1.4e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAN31674.1 - 5.4e-05 23.4 0.0 9.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TPR_19 PF14559.6 EAN31675.1 - 1.4e-16 60.8 6.7 5.5e-09 36.4 0.3 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAN31675.1 - 9.2e-16 56.6 9.0 0.068 13.3 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 EAN31675.1 - 2.1e-14 52.5 7.6 0.029 14.5 0.1 8.1 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAN31675.1 - 1.6e-11 44.3 1.7 0.05 13.9 0.0 6.1 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAN31675.1 - 3.1e-11 42.6 8.2 0.052 13.4 0.2 6.3 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EAN31675.1 - 6.6e-07 29.5 10.3 0.12 12.6 0.0 4.9 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EAN31675.1 - 8.1e-07 29.3 9.9 0.76 10.5 0.0 7.2 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAN31675.1 - 9.9e-07 29.3 0.0 0.057 14.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAN31675.1 - 1e-06 28.3 1.3 3.2 8.0 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAN31675.1 - 1.7e-06 28.0 15.5 0.00016 21.8 0.1 7.7 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 EAN31675.1 - 2.5e-05 24.5 4.0 0.13 12.6 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAN31675.1 - 4e-05 24.1 0.1 11 7.1 0.0 5.5 3 2 2 5 5 5 0 Tetratricopeptide repeat DUF3808 PF10300.9 EAN31675.1 - 8.9e-05 21.4 13.3 0.0012 17.7 0.1 4.2 4 1 1 5 5 5 2 Protein of unknown function (DUF3808) TPR_10 PF13374.6 EAN31675.1 - 0.0006 19.6 3.6 1.1 9.3 0.2 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4220 PF13968.6 EAN31675.1 - 0.0032 16.9 0.0 0.0095 15.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4220) PPR PF01535.20 EAN31675.1 - 0.011 15.9 0.6 30 5.1 0.0 4.4 5 0 0 5 5 4 0 PPR repeat ATP13 PF12921.7 EAN31675.1 - 0.027 14.3 0.6 1.3 8.9 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial ATPase expression TPR_11 PF13414.6 EAN31675.1 - 0.037 13.7 1.9 22 4.9 0.0 5.1 5 0 0 5 5 5 0 TPR repeat PPR_1 PF12854.7 EAN31675.1 - 0.18 11.5 2.1 4.3 7.1 0.3 3.0 3 0 0 3 3 3 0 PPR repeat LUC7 PF03194.15 EAN31675.1 - 0.3 10.7 4.6 3.6 7.2 2.3 2.9 3 1 0 3 3 3 0 LUC7 N_terminus Ribosomal_L19 PF01245.20 EAN31676.1 - 8.4e-14 51.4 0.0 8.4e-14 51.4 0.0 2.6 3 0 0 3 3 3 1 Ribosomal protein L19 Slu7 PF11708.8 EAN31677.1 - 2.4e-58 198.0 10.7 2.2e-57 194.9 10.7 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EAN31677.1 - 0.035 13.9 0.3 0.09 12.5 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle NifU PF01106.17 EAN31677.1 - 0.15 12.3 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 NifU-like domain DUF349 PF03993.12 EAN31677.1 - 2.2 8.7 6.8 0.48 10.8 2.7 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Ureide_permease PF07168.11 EAN31677.1 - 10 4.8 5.3 1.1 7.9 0.5 1.7 2 0 0 2 2 2 0 Ureide permease DHHC PF01529.20 EAN31678.1 - 2.6e-37 127.9 6.5 2.6e-37 127.9 6.5 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF4271 PF14093.6 EAN31678.1 - 0.018 14.9 4.5 0.018 14.9 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF4282 PF14110.6 EAN31678.1 - 0.66 10.7 0.1 0.66 10.7 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4282) DUF202 PF02656.15 EAN31678.1 - 3.3 8.2 5.4 0.4 11.1 0.3 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Nore1-SARAH PF16517.5 EAN31679.1 - 0.13 12.2 1.6 0.45 10.5 1.6 2.0 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain BetaGal_dom3 PF13363.6 EAN31680.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 PLDc_2 PF13091.6 EAN31681.1 - 7.6e-36 122.9 0.0 3.1e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EAN31681.1 - 2.6e-12 46.4 1.6 5e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif FAM83 PF07894.12 EAN31681.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 FAM83 A-H TPR_MLP1_2 PF07926.12 EAN31682.1 - 0.057 13.5 10.3 0.46 10.6 1.7 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TEX13 PF15186.6 EAN31682.1 - 0.7 9.6 3.7 0.47 10.1 0.9 2.1 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family TMF_DNA_bd PF12329.8 EAN31682.1 - 1.2 9.1 9.6 9.5 6.3 1.5 3.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PRKG1_interact PF15898.5 EAN31682.1 - 1.8 9.5 7.9 39 5.2 1.0 3.6 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Cnn_1N PF07989.11 EAN31682.1 - 2.3 8.4 10.0 1.4 9.1 0.6 3.3 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 EAN31682.1 - 3.3 7.9 11.7 1 9.6 1.9 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3972 PF13118.6 EAN31682.1 - 5.4 7.5 10.4 2.2 8.7 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3972) Adap_comp_sub PF00928.21 EAN31684.1 - 0.00046 19.6 0.5 0.00052 19.5 0.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family partial_CstF PF15861.5 EAN31685.1 - 0.027 14.2 1.0 0.062 13.1 1.0 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain RNA_pol_Rpb2_6 PF00562.28 EAN31686.1 - 5.1e-116 387.9 0.3 7.2e-116 387.5 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EAN31686.1 - 8.7e-31 107.0 0.0 1.3e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EAN31686.1 - 4.8e-26 90.7 0.0 1.4e-25 89.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 EAN31686.1 - 3.4e-20 72.3 0.1 8.6e-20 70.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 EAN31686.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain zf-ribbon_3 PF13248.6 EAN31686.1 - 0.23 10.9 1.2 1.2 8.7 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain MACPF PF01823.19 EAN31687.1 - 6.2e-30 104.9 1.4 1.1e-29 104.0 1.4 1.4 1 0 0 1 1 1 1 MAC/Perforin domain MACPF PF01823.19 EAN31689.1 - 4.6e-46 157.6 1.5 6.5e-46 157.1 1.5 1.2 1 0 0 1 1 1 1 MAC/Perforin domain MRP-L47 PF06984.13 EAN31690.1 - 4.4e-23 81.2 2.5 2.1e-22 79.0 0.0 2.4 3 0 0 3 3 3 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Seryl_tRNA_N PF02403.22 EAN31690.1 - 0.034 14.4 1.4 0.058 13.6 1.4 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain UPF0767 PF15990.5 EAN31691.1 - 9.4 6.5 13.9 1.2 9.3 0.3 4.7 4 1 0 4 4 4 0 UPF0767 family RNA_pol_Rpb2_6 PF00562.28 EAN31692.1 - 1.3e-123 413.0 0.0 2.5e-123 412.0 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EAN31692.1 - 3.7e-56 189.9 0.0 5.3e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EAN31692.1 - 2.3e-34 117.6 0.2 5.1e-34 116.5 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EAN31692.1 - 6.7e-32 110.7 0.8 3.6e-30 105.0 0.8 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 EAN31692.1 - 9e-27 93.1 0.0 2.1e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EAN31692.1 - 7.8e-22 77.3 0.1 1.7e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EAN31692.1 - 3.4e-18 65.9 2.1 3.4e-18 65.9 2.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 VIT1 PF01988.19 EAN31694.1 - 2e-39 135.7 2.6 2.6e-39 135.3 2.6 1.1 1 0 0 1 1 1 1 VIT family Kelch_1 PF01344.25 EAN31695.1 - 5.4e-46 153.9 13.9 1e-09 37.8 0.0 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_4 PF13418.6 EAN31695.1 - 6.3e-35 118.9 13.8 5.8e-10 39.0 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EAN31695.1 - 1.7e-32 110.6 12.5 6.5e-06 26.2 0.3 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EAN31695.1 - 3.9e-30 102.7 16.6 8.5e-06 25.6 0.1 7.4 7 0 0 7 7 7 6 Kelch motif Kelch_5 PF13854.6 EAN31695.1 - 4.8e-28 96.6 16.2 2.2e-09 37.1 0.4 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 EAN31695.1 - 1.3e-23 82.7 27.3 1.8e-05 24.9 0.5 7.2 7 1 0 7 7 7 6 Galactose oxidase, central domain BTB PF00651.31 EAN31695.1 - 2.2e-20 73.0 0.2 2.1e-19 69.8 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 EAN31695.1 - 0.097 12.8 0.1 1 9.5 0.0 2.4 2 0 0 2 2 2 0 BTB And C-terminal Kelch HTH_Bact PF18768.1 EAN31695.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix bacterial domain APG6_N PF17675.1 EAN31696.1 - 0.0061 17.1 11.5 0.0061 17.1 11.5 7.9 5 2 5 10 10 10 3 Apg6 coiled-coil region FAST_1 PF06743.15 EAN31697.1 - 0.12 12.3 5.3 0.62 10.1 0.0 3.5 3 2 0 3 3 3 0 FAST kinase-like protein, subdomain 1 UCR_hinge PF02320.16 EAN31699.1 - 4.8e-12 45.9 2.8 7e-12 45.4 2.8 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein PRP3 PF08572.10 EAN31700.1 - 5.8e-48 163.6 27.5 5.8e-48 163.6 27.5 3.1 2 2 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EAN31700.1 - 1e-30 106.7 0.1 1e-30 106.7 0.1 4.1 4 1 0 4 4 4 1 Protein of unknown function (DUF1115) FAM176 PF14851.6 EAN31700.1 - 8.2 6.1 16.7 3.7 7.2 0.3 3.5 3 0 0 3 3 3 0 FAM176 family HORMA PF02301.18 EAN31701.1 - 1.6e-23 83.4 2.6 2.2e-23 82.9 2.6 1.3 1 1 0 1 1 1 1 HORMA domain Ribosomal_S25 PF03297.15 EAN31701.1 - 0.001 19.2 1.0 0.04 14.1 0.0 2.8 3 0 0 3 3 3 1 S25 ribosomal protein DUF758 PF05527.11 EAN31701.1 - 0.17 11.8 2.2 8.3 6.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF758) Gar1 PF04410.14 EAN31702.1 - 3e-37 127.8 0.6 3.7e-37 127.5 0.6 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region FtsJ PF01728.19 EAN31703.1 - 1.1e-55 188.5 0.0 1.3e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase MFS_1 PF07690.16 EAN31704.1 - 0.00013 21.0 30.1 0.00013 21.0 30.1 3.6 1 1 2 3 3 3 2 Major Facilitator Superfamily LigT_PEase PF02834.16 EAN31705.1 - 0.00076 19.6 0.0 1.1 9.4 0.0 2.9 2 1 1 3 3 3 2 LigT like Phosphoesterase tRNA_lig_CPD PF08302.11 EAN31705.1 - 0.0021 17.6 0.8 0.51 9.8 0.0 2.6 3 0 0 3 3 3 2 Fungal tRNA ligase phosphodiesterase domain TetR_C_10 PF16295.5 EAN31705.1 - 0.16 12.3 1.5 0.56 10.5 0.2 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF2014 PF09427.10 EAN31706.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) TPM_phosphatase PF04536.14 EAN31707.1 - 0.029 14.5 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 TPM domain FAST_1 PF06743.15 EAN31708.1 - 0.016 15.2 0.4 0.044 13.7 0.3 1.9 1 1 0 1 1 1 0 FAST kinase-like protein, subdomain 1 SVA PF05326.11 EAN31708.1 - 0.05 13.6 0.3 0.099 12.6 0.3 1.6 1 1 0 1 1 1 0 Seminal vesicle autoantigen (SVA) RINGv PF12906.7 EAN31709.1 - 1.4e-12 47.5 8.9 3.1e-12 46.4 8.9 1.6 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 EAN31709.1 - 8.8e-12 45.2 1.0 1.5e-10 41.2 0.7 2.6 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EAN31709.1 - 1.4e-09 38.1 0.0 1.2e-08 35.1 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 EAN31709.1 - 0.15 12.4 5.3 0.47 10.8 5.3 1.9 1 0 0 1 1 1 0 Ring finger domain LSM PF01423.22 EAN31710.1 - 2.9e-14 52.5 0.8 3.5e-14 52.3 0.8 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAN31710.1 - 0.003 17.7 0.1 0.0039 17.3 0.1 1.4 1 1 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EAN31710.1 - 0.052 13.7 0.1 0.33 11.1 0.1 2.1 1 1 0 1 1 1 0 Scd6-like Sm domain DUF2362 PF10154.9 EAN31711.1 - 1.4e-10 40.8 2.9 1.4e-10 40.8 2.9 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2362) ESSS PF10183.9 EAN31711.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFAP1 PF06991.11 EAN31712.1 - 4.4e-56 190.1 23.0 4.4e-56 190.1 23.0 2.1 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing DUF974 PF06159.13 EAN31713.1 - 1.6e-05 24.8 0.1 2.1e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DUF11 PF01345.18 EAN31713.1 - 2 8.8 4.3 33 4.9 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function DUF11 WD40 PF00400.32 EAN31714.1 - 7.1e-13 48.8 8.1 1.7e-05 25.5 0.1 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN31714.1 - 1.6e-05 25.1 0.5 15 5.9 0.0 5.5 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 EAN31714.1 - 0.00063 19.2 0.2 0.0023 17.4 0.2 1.8 1 1 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region PQQ_3 PF13570.6 EAN31714.1 - 0.0027 18.2 1.4 21 5.7 0.0 4.8 5 0 0 5 5 5 1 PQQ-like domain IBN_N PF03810.19 EAN31715.1 - 8.7e-07 28.8 0.1 4.3e-05 23.3 0.1 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain HSP90 PF00183.18 EAN31715.1 - 0.028 13.3 0.7 0.055 12.4 0.1 1.7 2 0 0 2 2 2 0 Hsp90 protein DSHCT PF08148.12 EAN31716.1 - 5.1e-47 159.6 0.0 1.3e-46 158.3 0.0 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EAN31716.1 - 2.1e-19 69.9 0.0 5.6e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN31716.1 - 5.5e-07 29.9 3.2 5.2e-06 26.8 0.2 3.4 3 1 0 3 3 3 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.6 EAN31716.1 - 1.6e-06 28.3 13.0 1.2e-05 25.4 8.6 3.2 2 1 0 2 2 2 1 rRNA-processing arch domain ResIII PF04851.15 EAN31716.1 - 1.9e-06 28.0 0.0 8.3e-06 25.9 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S9 PF00326.21 EAN31717.1 - 1.9e-26 92.9 0.0 3e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Proteasome PF00227.26 EAN31718.1 - 2.6e-26 92.3 0.1 5.9e-26 91.1 0.1 1.6 1 1 1 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 EAN31718.1 - 2.9e-13 49.2 0.0 5.1e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature tRNA-synt_1b PF00579.25 EAN31719.1 - 2.1e-49 168.5 0.0 2.6e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) VWA_2 PF13519.6 EAN31720.1 - 3.1e-12 47.1 0.4 1.3e-11 45.1 0.0 2.1 3 0 0 3 3 3 1 von Willebrand factor type A domain Glutaredoxin PF00462.24 EAN31720.1 - 0.047 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Effector_1 PF04518.12 EAN31720.1 - 0.17 11.0 1.5 0.69 9.0 0.0 2.3 3 0 0 3 3 3 0 Effector from type III secretion system XRN_N PF03159.18 EAN31721.1 - 2.3e-95 318.6 0.1 1.3e-94 316.2 0.0 2.4 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EAN31721.1 - 1.1e-91 308.0 17.7 1.3e-54 185.9 3.2 3.2 3 1 1 4 4 4 2 Xrn1 helical domain baeRF_family12 PF18856.1 EAN31721.1 - 0.36 11.4 1.8 1.4 9.5 1.8 2.0 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 Cnd1 PF12717.7 EAN31722.1 - 5.3e-25 88.3 0.6 5.3e-25 88.3 0.6 4.4 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.7 EAN31722.1 - 1.1e-05 25.5 2.8 0.069 13.1 0.0 5.3 3 1 0 3 3 3 1 Sister chromatid cohesion C-terminus HEAT PF02985.22 EAN31722.1 - 0.059 13.6 0.1 1.2 9.6 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat Vac14_Fab1_bd PF12755.7 EAN31722.1 - 0.12 13.0 0.4 5.5 7.7 0.0 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RBR PF17208.3 EAN31722.1 - 1.2 9.8 7.6 0.14 12.9 0.8 2.4 2 0 0 2 2 2 0 RNA binding Region Zip PF02535.22 EAN31723.1 - 0.079 12.2 9.6 0.094 11.9 9.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Membralin PF09746.9 EAN31723.1 - 0.15 11.0 8.3 0.2 10.7 8.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Ndc1_Nup PF09531.10 EAN31723.1 - 0.49 9.0 10.8 0.48 9.1 10.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dsh_C PF12316.8 EAN31723.1 - 0.55 10.6 11.0 0.75 10.2 11.0 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Pneumo_att_G PF05539.11 EAN31723.1 - 0.71 9.4 17.9 0.9 9.1 17.9 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SOBP PF15279.6 EAN31723.1 - 1.5 9.4 14.2 1.8 9.1 14.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GREB1 PF15782.5 EAN31723.1 - 4.5 4.3 14.6 4.6 4.2 14.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SWIRM-assoc_2 PF16496.5 EAN31723.1 - 6.9 5.4 28.9 8.6 5.1 28.9 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal SWI-SNF_Ssr4 PF08549.10 EAN31723.1 - 7.9 5.0 16.1 9.7 4.7 16.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Noggin PF05806.12 EAN31723.1 - 8 6.3 10.2 11 5.8 10.2 1.1 1 0 0 1 1 1 0 Noggin RR_TM4-6 PF06459.12 EAN31723.1 - 8.6 6.1 28.2 11 5.7 28.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Thioredoxin_8 PF13905.6 EAN31725.1 - 4.3e-31 107.1 0.4 2.7e-16 59.7 0.1 3.5 3 0 0 3 3 3 2 Thioredoxin-like RabGAP-TBC PF00566.18 EAN31726.1 - 1.2e-47 162.4 7.3 1.7e-47 161.9 7.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Nop16 PF09420.10 EAN31727.1 - 0.12 12.4 0.9 0.22 11.5 0.9 1.6 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 ScsC_N PF18312.1 EAN31727.1 - 0.19 11.6 0.4 0.39 10.6 0.4 1.5 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain ANAPC4_WD40 PF12894.7 EAN31728.1 - 0.0078 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAN31728.1 - 0.031 15.1 0.2 19 6.3 0.0 3.5 3 1 0 3 3 3 0 WD domain, G-beta repeat WD40 PF00400.32 EAN31729.1 - 0.012 16.5 0.0 2 9.4 0.0 4.0 3 0 0 3 3 3 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN31729.1 - 0.048 14.0 0.0 32 4.9 0.0 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CBFD_NFYB_HMF PF00808.23 EAN31731.1 - 0.00017 21.8 0.0 0.00028 21.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAN31731.1 - 0.00025 21.4 0.0 0.00041 20.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FAM76 PF16046.5 EAN31731.1 - 0.035 13.5 1.2 0.044 13.1 1.2 1.1 1 0 0 1 1 1 0 FAM76 protein DivIC PF04977.15 EAN31731.1 - 9.5 6.1 13.3 1.1 9.1 4.0 2.5 2 1 0 2 2 2 0 Septum formation initiator Rep_fac_C PF08542.11 EAN31732.1 - 3.5e-15 56.2 0.1 8.9e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EAN31732.1 - 4.6e-15 55.8 0.1 2.4e-13 50.2 0.1 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EAN31732.1 - 1.3e-13 51.5 0.0 2.3e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EAN31732.1 - 1.1e-08 35.3 0.0 2.2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EAN31732.1 - 8.5e-06 25.6 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EAN31732.1 - 9.8e-06 25.8 0.0 3.1e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 EAN31732.1 - 1.3e-05 25.5 0.4 0.00014 22.1 0.2 2.4 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EAN31732.1 - 2.6e-05 24.6 0.0 0.00091 19.6 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EAN31732.1 - 5e-05 23.1 0.1 0.00025 20.8 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EAN31732.1 - 0.00031 21.1 0.0 0.003 17.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EAN31732.1 - 0.00035 20.5 0.0 0.0013 18.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 EAN31732.1 - 0.00035 20.6 0.0 0.00078 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EAN31732.1 - 0.0028 17.4 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAN31732.1 - 0.0029 17.6 0.0 0.084 12.9 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 EAN31732.1 - 0.004 17.1 0.0 0.013 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 EAN31732.1 - 0.0045 16.8 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_23 PF13476.6 EAN31732.1 - 0.0057 17.2 0.1 0.015 15.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EAN31732.1 - 0.0084 15.9 0.2 0.18 11.5 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase Mg_chelatase PF01078.21 EAN31732.1 - 0.0092 15.4 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 EAN31732.1 - 0.0093 15.4 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein DUF2075 PF09848.9 EAN31732.1 - 0.02 14.2 0.0 0.047 12.9 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 EAN31732.1 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EAN31732.1 - 0.035 14.6 0.0 0.073 13.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter TIP49_C PF17856.1 EAN31732.1 - 0.086 13.0 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 TIP49 AAA-lid domain TK PF00265.18 EAN31732.1 - 0.096 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase Viral_helicase1 PF01443.18 EAN31732.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EAN31732.1 - 0.13 12.2 0.0 0.41 10.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAN31732.1 - 0.19 11.8 0.2 0.49 10.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAN31733.1 - 1.7e-11 44.6 0.2 1.5e-10 41.6 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EAN31733.1 - 0.0019 18.2 0.1 0.0019 18.2 0.1 2.7 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 EAN31733.1 - 0.012 15.5 0.0 0.15 12.0 0.0 2.6 2 1 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 EAN31733.1 - 0.022 15.3 7.9 0.38 11.2 0.1 2.7 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 EAN31733.1 - 0.053 14.1 1.7 0.16 12.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EAN31733.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 EAN31733.1 - 0.12 12.7 0.0 0.44 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EAN31733.1 - 0.14 12.7 0.3 0.36 11.3 0.0 1.9 3 0 0 3 3 3 0 ABC transporter DUF4795 PF16043.5 EAN31733.1 - 0.14 11.7 0.6 3.7 7.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) FapA PF03961.13 EAN31734.1 - 0.082 11.5 0.7 0.13 10.9 0.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Gp_dh_C PF02800.20 EAN31735.1 - 1.5e-66 222.9 0.1 2.1e-66 222.4 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EAN31735.1 - 2.5e-33 114.4 0.0 7.7e-33 112.9 0.0 1.9 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EAN31735.1 - 0.0012 18.8 0.1 0.006 16.6 0.1 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase DapB_N PF01113.20 EAN31735.1 - 0.03 14.4 0.5 0.1 12.7 0.2 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Cytochrom_C1 PF02167.15 EAN31736.1 - 2.4e-88 295.5 0.0 3.7e-88 294.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EAN31736.1 - 0.0057 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EAN31736.1 - 0.032 15.4 0.0 0.097 13.8 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c zf-met PF12874.7 EAN31737.1 - 3.6e-06 27.2 4.1 6.8e-06 26.3 4.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EAN31737.1 - 9.4e-06 25.8 4.1 2.3e-05 24.6 4.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 EAN31737.1 - 0.013 15.3 0.6 0.013 15.3 0.6 1.9 2 0 0 2 2 2 0 U1 zinc finger efThoc1 PF11957.8 EAN31737.1 - 0.036 12.7 9.5 0.049 12.3 9.5 1.2 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor zf-C2H2_2 PF12756.7 EAN31737.1 - 0.063 13.6 0.1 0.063 13.6 0.1 2.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) TPR_MLP1_2 PF07926.12 EAN31737.1 - 0.17 11.9 13.1 0.31 11.1 11.9 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FapA PF03961.13 EAN31737.1 - 0.51 8.9 7.5 0.58 8.7 7.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3552 PF12072.8 EAN31737.1 - 6.5 6.1 17.8 11 5.3 17.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) ALMT PF11744.8 EAN31737.1 - 9 5.0 8.6 11 4.7 8.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF5411 PF17424.2 EAN31738.1 - 0.02 14.8 1.3 0.86 9.6 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5411) COG2 PF06148.11 EAN31738.1 - 0.055 13.6 5.4 0.99 9.5 0.5 2.6 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SNARE PF05739.19 EAN31738.1 - 0.12 12.3 0.1 0.53 10.3 0.0 2.1 2 1 0 2 2 2 0 SNARE domain DUF4548 PF15081.6 EAN31738.1 - 0.41 10.5 3.3 0.65 9.8 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4548) Peptidase_S49_N PF08496.10 EAN31738.1 - 1.7 8.7 6.4 0.4 10.7 1.0 2.4 2 1 0 2 2 2 0 Peptidase family S49 N-terminal TMF_TATA_bd PF12325.8 EAN31738.1 - 3.6 7.8 9.6 0.13 12.5 2.5 2.2 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Ribosomal_L13 PF00572.18 EAN31739.1 - 1.9e-09 37.8 1.1 5.7e-08 33.1 0.1 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 PI3_PI4_kinase PF00454.27 EAN31740.1 - 3.3e-29 102.4 2.3 7.5e-28 98.0 2.3 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase tRNA-synt_1d PF00750.19 EAN31741.1 - 1.4e-112 376.1 4.4 6.1e-96 321.4 0.2 2.5 2 1 1 3 3 3 2 tRNA synthetases class I (R) DALR_1 PF05746.15 EAN31741.1 - 3.4e-27 95.0 0.3 5.7e-26 91.0 0.0 2.7 2 1 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EAN31741.1 - 1.6e-14 54.2 0.0 5.1e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain BBL5 PF07289.11 EAN31742.1 - 0.02 14.0 0.2 0.027 13.5 0.2 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein SLBP_RNA_bind PF15247.6 EAN31743.1 - 1.3e-16 60.5 6.5 1.7e-16 60.1 5.4 1.7 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain Ribosomal_L14 PF00238.19 EAN31744.1 - 1.1e-21 77.1 1.7 1.4e-21 76.9 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF2179 PF10035.9 EAN31744.1 - 0.019 14.7 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) RRM_1 PF00076.22 EAN31745.1 - 2.7e-18 65.6 0.0 4.5e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAN31745.1 - 0.025 14.6 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EAN31745.1 - 0.039 13.8 0.0 0.073 12.9 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif DUF5549 PF17703.1 EAN31745.1 - 5.1 6.7 6.3 7.8 6.1 6.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Ribosomal_L22e PF01776.17 EAN31746.1 - 2.4e-45 153.4 1.9 3e-45 153.1 1.9 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family AdoMet_Synthase PF01941.19 EAN31746.1 - 0.0026 16.6 0.2 0.003 16.4 0.2 1.1 1 0 0 1 1 1 1 S-adenosylmethionine synthetase (AdoMet synthetase) RPN7 PF10602.9 EAN31747.1 - 8.2e-53 178.7 2.1 8.2e-53 178.7 2.1 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EAN31747.1 - 5.8e-16 58.9 1.2 4.3e-15 56.1 0.2 2.6 3 0 0 3 3 3 1 PCI domain TPR_8 PF13181.6 EAN31747.1 - 0.0053 16.9 0.8 0.042 14.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAN31747.1 - 0.0074 16.1 0.4 0.034 14.0 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAN31747.1 - 0.07 13.3 0.0 8.2 6.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAN31747.1 - 0.088 12.9 0.0 0.88 9.7 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PCI PF01399.27 EAN31748.1 - 4.2e-16 59.3 0.5 4.2e-16 59.3 0.5 2.4 3 0 0 3 3 3 1 PCI domain Gag_p17 PF00540.18 EAN31748.1 - 0.0014 18.6 0.1 1.7 8.6 0.0 2.4 2 0 0 2 2 2 2 gag gene protein p17 (matrix protein) eIF3m_C_helix PF18005.1 EAN31748.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix COMM_domain PF07258.14 EAN31748.1 - 0.71 10.0 3.3 0.99 9.6 0.1 2.8 3 0 0 3 3 3 0 COMM domain NOT2_3_5 PF04153.18 EAN31749.1 - 4.8e-15 55.8 8.5 1.5e-14 54.2 8.5 2.0 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Symplekin_C PF12295.8 EAN31750.1 - 2.7e-27 96.1 4.0 2.7e-27 96.1 4.0 3.6 4 0 0 4 4 4 1 Symplekin tight junction protein C terminal U3snoRNP10 PF12397.8 EAN31750.1 - 0.00031 21.1 4.9 0.0011 19.3 0.2 3.7 3 1 1 4 4 4 1 U3 small nucleolar RNA-associated protein 10 DUF3854 PF12965.7 EAN31751.1 - 0.0097 15.9 0.2 5.6 7.0 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3854) RRM_1 PF00076.22 EAN31752.1 - 7.7e-56 185.8 16.9 7.3e-15 54.6 0.1 7.7 6 2 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAN31752.1 - 9.2e-08 31.7 0.2 3.7e-05 23.3 0.1 4.0 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EAN31752.1 - 0.00019 21.6 2.4 0.14 12.4 0.1 4.3 4 0 0 4 4 4 1 BRCA1-associated protein 2 RRM_occluded PF16842.5 EAN31752.1 - 0.01 15.7 0.1 0.23 11.4 0.0 3.1 2 1 0 2 2 2 1 Occluded RNA-recognition motif RRM_8 PF11835.8 EAN31752.1 - 0.048 13.9 0.0 33 4.8 0.0 3.5 3 0 0 3 3 3 0 RRM-like domain RRM_2 PF04059.12 EAN31752.1 - 1.8 8.9 8.1 0.87 9.8 1.1 3.8 3 1 0 3 3 3 0 RNA recognition motif 2 TP6A_N PF04406.14 EAN31753.1 - 4e-13 49.1 0.7 6.9e-13 48.4 0.7 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Myb_DNA-binding PF00249.31 EAN31754.1 - 3.5e-13 49.5 0.4 1.3e-06 28.5 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain DnaJ PF00226.31 EAN31754.1 - 1.1e-07 31.8 0.5 1.1e-07 31.8 0.5 4.0 4 1 0 4 4 4 1 DnaJ domain Myb_DNA-bind_6 PF13921.6 EAN31754.1 - 0.00042 20.5 0.0 0.017 15.3 0.0 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Histone PF00125.24 EAN31756.1 - 1.6e-15 57.6 0.1 1.9e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAN31756.1 - 4.6e-05 23.6 0.0 9.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EAN31756.1 - 0.026 15.0 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RP-C PF03428.13 EAN31756.1 - 0.1 12.2 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Replication protein C N-terminal domain FAINT PF04385.15 EAN31758.1 - 2e-07 30.9 3.9 7.5e-06 25.9 0.8 2.7 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31759.1 - 0.0016 18.4 24.8 0.051 13.6 1.6 4.5 3 1 1 4 4 4 3 Domain of unknown function, DUF529 DFRP_C PF16543.5 EAN31759.1 - 0.11 13.0 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 FAINT PF04385.15 EAN31760.1 - 2.6e-06 27.4 7.9 0.0003 20.8 0.9 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 SMC_N PF02463.19 EAN31761.1 - 2e-63 213.8 0.0 1.4e-62 211.1 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EAN31761.1 - 6.7e-12 45.7 0.1 1.1e-09 38.6 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EAN31761.1 - 3.8e-09 36.8 10.9 0.00022 21.2 2.1 3.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ATG16 PF08614.11 EAN31761.1 - 3.1e-07 30.8 78.1 0.0029 17.8 11.4 6.1 3 2 2 5 5 5 3 Autophagy protein 16 (ATG16) ERM PF00769.19 EAN31761.1 - 0.0049 16.7 0.5 0.0049 16.7 0.5 5.4 4 1 1 5 5 5 1 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 EAN31761.1 - 0.0069 17.0 10.0 0.0069 17.0 10.0 8.2 3 2 4 8 8 7 1 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_29 PF13555.6 EAN31761.1 - 0.013 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Spc7 PF08317.11 EAN31761.1 - 0.014 14.3 94.8 0.035 13.0 11.2 6.7 3 2 3 6 6 6 0 Spc7 kinetochore protein ABC_tran PF00005.27 EAN31761.1 - 0.014 15.9 0.1 0.014 15.9 0.1 6.0 3 1 1 5 5 4 0 ABC transporter Fez1 PF06818.15 EAN31761.1 - 0.31 11.5 81.4 0.088 13.3 14.3 5.7 3 2 2 5 5 5 0 Fez1 Myosin_tail_1 PF01576.19 EAN31761.1 - 0.39 8.5 84.5 0.034 12.0 27.7 3.9 3 1 0 3 3 3 0 Myosin tail AAA_15 PF13175.6 EAN31761.1 - 0.6 9.8 73.2 0.063 13.0 27.8 5.0 1 1 0 3 3 2 0 AAA ATPase domain AAA_13 PF13166.6 EAN31761.1 - 0.96 8.0 82.6 0.047 12.4 15.4 5.5 4 2 2 6 6 6 0 AAA domain APG6_N PF17675.1 EAN31761.1 - 2.9 8.4 94.8 0.14 12.7 10.1 7.7 4 2 2 6 6 6 0 Apg6 coiled-coil region DUF1843 PF08898.10 EAN31761.1 - 3.8 8.1 6.6 1 9.9 0.0 3.6 3 2 1 4 4 4 0 Domain of unknown function (DUF1843) PP2C PF00481.21 EAN31762.1 - 7.4e-37 127.4 0.0 9e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EAN31762.1 - 3.1e-05 23.7 0.0 7.2e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Pet127 PF08634.10 EAN31762.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial protein Pet127 Ydc2-catalyt PF09159.10 EAN31762.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 AHJR-like PF18743.1 EAN31764.1 - 0.0038 16.8 0.1 0.79 9.3 0.0 2.3 2 0 0 2 2 2 2 REase_AHJR-like COX6A PF02046.15 EAN31765.1 - 0.00013 22.4 0.2 0.0002 21.8 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Sld5 PF05916.11 EAN31766.1 - 0.033 14.6 0.3 0.22 12.0 0.1 2.5 3 0 0 3 3 3 0 GINS complex protein FXMR_C2 PF16098.5 EAN31767.1 - 0.021 15.3 0.1 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 Fragile X-related mental retardation protein C-terminal region 2 Lactamase_B_2 PF12706.7 EAN31768.1 - 3.2e-25 88.8 0.0 1.5e-19 70.3 0.1 2.6 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAN31768.1 - 5.5e-06 26.5 0.0 0.0022 18.1 0.2 2.6 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 EAN31768.1 - 1.5e-05 24.6 0.0 5.9e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_6 PF16661.5 EAN31768.1 - 0.0015 18.0 0.1 0.32 10.4 0.1 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily domain BK_channel_a PF03493.18 EAN31769.1 - 4.8e-15 55.5 0.1 1.2e-14 54.2 0.1 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EAN31769.1 - 0.00024 21.0 3.3 0.00024 21.0 3.3 3.2 3 2 1 4 4 4 1 Ion channel Chordopox_A33R PF05966.12 EAN31769.1 - 0.027 13.8 0.3 0.077 12.3 0.3 1.7 1 0 0 1 1 1 0 Chordopoxvirus A33R protein ISK_Channel PF02060.15 EAN31772.1 - 0.032 14.0 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 Slow voltage-gated potassium channel PEN-2 PF10251.9 EAN31772.1 - 0.033 14.6 0.1 0.084 13.3 0.1 1.6 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase DUF4834 PF16118.5 EAN31772.1 - 4 8.5 0.0 4 8.5 0.0 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Macoilin PF09726.9 EAN31772.1 - 5.5 5.4 25.5 0.35 9.4 20.0 1.7 2 1 0 2 2 2 0 Macoilin family Ribosomal_S3_C PF00189.20 EAN31773.1 - 4e-25 88.2 0.8 2e-24 85.9 2.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EAN31773.1 - 1.9e-09 37.2 0.0 3.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 EAN31773.1 - 0.02 15.4 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 EAN31773.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus Kelch_5 PF13854.6 EAN31775.1 - 7e-33 112.1 3.9 6.5e-08 32.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Metallophos PF00149.28 EAN31775.1 - 8.9e-31 108.0 0.0 2.2e-30 106.7 0.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_4 PF13418.6 EAN31775.1 - 2.2e-30 104.4 12.2 8.3e-13 48.1 0.4 6.5 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EAN31775.1 - 6.5e-29 99.6 14.0 1.3e-06 28.6 0.0 7.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EAN31775.1 - 8.3e-22 76.7 8.6 8.1e-05 22.8 0.1 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EAN31775.1 - 1.1e-21 75.9 4.8 1.6e-05 24.7 0.1 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EAN31775.1 - 8.2e-20 70.1 1.8 4.4e-05 23.0 0.0 6.4 6 0 0 6 6 6 3 Kelch motif RAG2 PF03089.14 EAN31775.1 - 0.00014 21.0 0.1 2.6 7.0 0.0 3.8 2 1 1 4 4 4 2 Recombination activating protein 2 PDDEXK_3 PF13366.6 EAN31775.1 - 0.0092 16.3 0.1 0.017 15.5 0.1 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily PC_rep PF01851.22 EAN31776.1 - 1.3e-25 88.5 9.8 3.5e-05 24.0 0.1 9.1 8 0 0 8 8 8 5 Proteasome/cyclosome repeat RPN2_C PF18004.1 EAN31776.1 - 3e-20 72.7 0.0 6e-19 68.5 0.0 2.2 1 1 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 EAN31776.1 - 6.4e-16 58.5 0.0 1.8e-11 44.2 0.0 4.3 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 EAN31776.1 - 8.7e-05 22.5 0.5 6.1 7.4 0.1 5.8 6 0 0 6 6 6 1 HEAT repeat ANAPC3 PF12895.7 EAN31776.1 - 0.35 11.1 6.8 3.6 7.9 0.9 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 FAINT PF04385.15 EAN31777.1 - 8.2e-12 45.0 11.6 2.6e-06 27.4 0.0 3.7 4 0 0 4 4 4 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN31778.1 - 5.9e-20 71.1 39.0 1.3e-05 25.1 1.0 7.8 8 1 0 8 8 8 5 Domain of unknown function, DUF529 PmoA PF14100.6 EAN31778.1 - 0.0021 17.6 0.0 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 Methane oxygenase PmoA FAINT PF04385.15 EAN31779.1 - 4e-21 74.9 30.5 4.8e-08 33.0 0.0 7.7 7 1 1 8 8 8 5 Domain of unknown function, DUF529 DUF2922 PF11148.8 EAN31779.1 - 0.011 15.4 0.1 0.48 10.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) Rhomboid_SP PF12595.8 EAN31779.1 - 0.076 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Rhomboid serine protease AP2 PF00847.20 EAN31780.1 - 5.4e-15 55.4 0.2 5.4e-15 55.4 0.2 2.1 2 0 0 2 2 2 1 AP2 domain RCDG1 PF15725.5 EAN31780.1 - 5.1 7.6 8.0 39 4.8 0.6 3.4 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein UPF0113_N PF17833.1 EAN31782.1 - 9e-34 115.9 1.4 1.5e-33 115.2 0.6 1.7 2 0 0 2 2 2 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EAN31782.1 - 2e-21 76.0 0.0 4.7e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain NOC3p PF07540.11 EAN31783.1 - 0.00047 20.5 1.0 0.0014 19.0 0.0 2.4 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 EAN31783.1 - 0.024 14.7 0.4 1.1 9.2 0.4 2.8 1 1 0 1 1 1 0 CBF/Mak21 family Pox_polyA_pol_N PF12630.7 EAN31784.1 - 0.0018 18.6 0.9 0.0018 18.6 0.9 2.2 2 0 0 2 2 1 1 Poxvirus poly(A) polymerase N-terminal domain Cep57_CLD_2 PF14197.6 EAN31784.1 - 0.0023 18.0 1.3 0.0023 18.0 1.3 4.3 3 1 1 4 4 4 3 Centrosome localisation domain of PPC89 TSC22 PF01166.18 EAN31784.1 - 0.011 16.1 13.5 0.8 10.1 3.2 4.2 3 0 0 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.21 EAN31784.1 - 0.015 15.4 0.8 0.015 15.4 0.8 4.2 4 0 0 4 4 3 0 bZIP transcription factor DUF3450 PF11932.8 EAN31784.1 - 0.016 14.5 14.7 0.47 9.7 6.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 EAN31784.1 - 0.027 14.8 19.6 0.86 10.0 6.3 4.6 2 1 2 4 4 4 0 Csm1 N-terminal domain WD40_alt PF14077.6 EAN31784.1 - 0.028 14.3 0.1 0.079 12.8 0.1 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF4140 PF13600.6 EAN31784.1 - 0.095 13.2 6.5 2.2 8.8 0.5 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 EAN31784.1 - 0.76 10.5 21.3 0.95 10.1 1.0 4.1 2 1 1 3 3 3 0 Initiation control protein YabA JIP_LZII PF16471.5 EAN31784.1 - 1.3 9.3 11.2 1.3 9.2 0.5 3.6 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II CENP-H PF05837.12 EAN31784.1 - 1.4 9.4 19.6 0.034 14.6 5.3 3.7 1 1 1 3 3 3 0 Centromere protein H (CENP-H) bZIP_2 PF07716.15 EAN31784.1 - 2.5 8.3 9.6 11 6.3 0.0 3.6 3 0 0 3 3 3 0 Basic region leucine zipper YL1 PF05764.13 EAN31786.1 - 1.3e-30 107.3 24.5 1.3e-30 107.3 24.5 1.9 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 EAN31786.1 - 2e-12 46.7 0.1 5.1e-12 45.3 0.1 1.8 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RBD-FIP PF09457.10 EAN31786.1 - 2.5 8.1 6.0 2.1 8.3 0.7 2.5 2 0 0 2 2 2 0 FIP domain PH PF00169.29 EAN31787.1 - 0.62 10.6 7.8 0.2 12.2 2.4 3.2 3 1 0 3 3 3 0 PH domain Pex24p PF06398.11 EAN31787.1 - 4 6.3 35.6 0.41 9.6 1.8 5.7 4 2 2 6 6 6 0 Integral peroxisomal membrane peroxin Csm2_III-A PF03750.13 EAN31787.1 - 4 8.3 6.5 48 4.8 0.0 4.1 4 0 0 4 4 4 0 Csm2 Type III-A vATP-synt_AC39 PF01992.16 EAN31788.1 - 1.3e-93 314.2 4.3 1.5e-93 314.0 4.3 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit FAINT PF04385.15 EAN31789.1 - 8.3e-15 54.6 4.3 0.0058 16.7 0.0 4.5 4 0 0 4 4 4 4 Domain of unknown function, DUF529 Rpn3_C PF08375.11 EAN31791.1 - 5.5e-19 68.4 0.1 1.9e-18 66.6 0.1 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EAN31791.1 - 2.8e-17 63.1 0.1 7.4e-17 61.8 0.1 1.8 1 0 0 1 1 1 1 PCI domain Phage_term_smal PF05944.12 EAN31791.1 - 0.075 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Phage small terminase subunit DUF4441 PF14536.6 EAN31791.1 - 0.093 12.9 0.2 0.3 11.3 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) CSN8_PSD8_EIF3K PF10075.9 EAN31791.1 - 0.11 12.5 0.5 0.79 9.7 0.0 2.4 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family TPR_2 PF07719.17 EAN31791.1 - 0.23 11.7 5.9 1 9.6 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAN31791.1 - 1.9 8.8 5.4 3 8.1 2.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CEP209_CC5 PF16574.5 EAN31792.1 - 0.001 19.2 8.3 0.001 19.2 8.3 5.2 3 1 0 5 5 5 2 Coiled-coil region of centrosome protein CE290 YtxH PF12732.7 EAN31792.1 - 5.4 7.6 20.5 1.7e+02 2.8 5.6 6.3 2 2 0 2 2 2 0 YtxH-like protein ATP-synt_ab PF00006.25 EAN31793.1 - 2.4e-65 220.2 0.0 3.2e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EAN31793.1 - 1.1e-11 45.1 1.3 1.8e-11 44.4 1.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain BRCT_2 PF16589.5 EAN31795.1 - 0.023 15.1 0.2 0.84 10.1 0.0 2.4 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain JAB PF01398.21 EAN31796.1 - 5.1e-09 36.1 0.1 8.4e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EAN31796.1 - 0.00084 19.7 0.7 0.0012 19.3 0.7 1.5 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function Cyclin_N PF00134.23 EAN31797.1 - 1.9e-05 24.4 1.0 7.3e-05 22.5 1.0 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 EAN31798.1 - 1.1e-33 116.7 0.3 1.5e-33 116.3 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN31798.1 - 7.3e-24 84.5 0.1 1e-23 83.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAN31798.1 - 0.018 14.4 0.3 0.082 12.2 0.3 1.9 1 1 0 1 1 1 0 Kinase-like zf-CCCH PF00642.24 EAN31799.1 - 3.1e-08 33.3 19.4 2.7e-05 24.0 1.9 4.1 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAN31799.1 - 1.5e-06 28.0 26.0 2.2e-06 27.5 5.2 4.3 4 0 0 4 4 4 2 Zinc finger domain Torus PF16131.5 EAN31799.1 - 0.001 19.8 17.4 0.031 15.0 2.2 3.3 1 1 2 3 3 3 3 Torus domain zf-CCCH_3 PF15663.5 EAN31799.1 - 0.0052 17.0 13.3 0.0086 16.3 9.0 2.3 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 EAN31799.1 - 0.041 13.7 2.2 0.041 13.7 2.2 4.4 4 0 0 4 4 4 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EAN31799.1 - 4.7 7.8 21.3 0.18 12.4 2.4 3.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger EF-hand_7 PF13499.6 EAN31800.1 - 0.0023 18.4 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair DUF1408 PF07193.11 EAN31801.1 - 0.17 12.0 0.2 0.58 10.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1408) Fumble PF03630.14 EAN31802.1 - 4.3e-23 82.0 0.3 4.3e-23 82.0 0.3 1.7 2 0 0 2 2 2 1 Fumble Pilin_GH PF16734.5 EAN31802.1 - 0.055 13.8 0.6 0.13 12.6 0.6 1.6 1 0 0 1 1 1 0 Type IV pilin-like G and H, putative PI3K_P85_iSH2 PF16454.5 EAN31802.1 - 8.3 6.0 8.3 58 3.2 5.8 2.6 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DIX PF00778.17 EAN31803.1 - 1.7e-09 37.3 0.0 2.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 DIX domain Rad51 PF08423.11 EAN31805.1 - 9.3e-28 97.2 0.0 1.3e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 EAN31805.1 - 1.4e-07 31.1 0.9 3.9e-07 29.7 0.9 1.7 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 EAN31805.1 - 2.6e-07 30.4 0.0 4.6e-07 29.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 EAN31805.1 - 1.1e-06 28.4 0.0 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 EAN31805.1 - 4.2e-06 26.3 0.5 1.3e-05 24.7 0.5 1.6 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 EAN31805.1 - 6.7e-06 26.0 0.5 1.4e-05 24.9 0.5 1.5 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EAN31805.1 - 8.6e-06 25.8 0.6 1.3e-05 25.3 0.6 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EAN31805.1 - 0.00018 22.0 0.1 0.00047 20.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAN31805.1 - 0.001 19.3 0.0 0.0026 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAN31805.1 - 0.0033 17.8 0.6 0.013 15.9 0.2 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PAXNEB PF05625.11 EAN31805.1 - 0.023 13.8 0.6 0.68 9.0 0.1 2.0 1 1 1 2 2 2 0 PAXNEB protein NACHT PF05729.12 EAN31805.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.5 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EAN31805.1 - 0.041 14.3 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.9 EAN31805.1 - 0.045 13.0 0.1 0.09 12.0 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 EAN31805.1 - 0.05 13.6 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EAN31805.1 - 0.093 12.5 0.1 0.55 9.9 0.0 2.2 1 1 2 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 EAN31805.1 - 0.15 12.2 0.1 0.23 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAN31805.1 - 0.24 11.9 0.7 0.45 11.0 0.7 1.7 1 1 0 1 1 1 0 ABC transporter TLD PF07534.16 EAN31806.1 - 1.1e-20 74.3 0.6 6.8e-20 71.7 0.1 2.7 2 0 0 2 2 2 1 TLD RabGAP-TBC PF00566.18 EAN31806.1 - 1.4e-08 34.6 3.3 2.8e-08 33.7 3.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IMCp PF12314.8 EAN31808.1 - 6.2e-26 90.5 104.7 2.1e-16 60.0 44.7 3.8 1 1 2 3 3 3 3 Inner membrane complex protein 2-oxoacid_dh PF00198.23 EAN31809.1 - 1.8e-63 214.1 0.1 2.5e-63 213.6 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EAN31809.1 - 1.1e-19 70.0 2.6 2.1e-19 69.1 2.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EAN31809.1 - 7.3e-05 22.5 0.1 0.00015 21.5 0.1 1.4 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_D23 PF16576.5 EAN31809.1 - 0.00019 20.7 0.1 0.00046 19.5 0.1 1.6 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 EAN31809.1 - 0.069 13.0 0.4 0.13 12.2 0.4 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein GCP_N_terminal PF17681.1 EAN31810.1 - 1.9e-15 57.3 0.5 3.8e-15 56.3 0.5 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EAN31810.1 - 1.9e-15 57.1 12.1 1.9e-15 57.1 12.1 2.2 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal Ank_2 PF12796.7 EAN31811.1 - 9.1e-24 83.9 0.1 1.7e-09 38.1 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DHHC PF01529.20 EAN31811.1 - 7e-23 81.2 15.3 7e-23 81.2 15.3 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 EAN31811.1 - 2.9e-20 72.4 1.1 7.5e-07 29.6 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAN31811.1 - 9.4e-16 57.7 1.6 3e-07 30.6 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAN31811.1 - 2.5e-14 52.0 0.4 0.0059 17.0 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EAN31811.1 - 6.7e-12 45.3 1.3 0.0023 18.3 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat IGFBP PF00219.18 EAN31811.1 - 0.38 11.4 6.5 0.85 10.3 6.5 1.5 1 0 0 1 1 1 0 Insulin-like growth factor binding protein LNS2 PF08235.13 EAN31812.1 - 1.4e-91 306.0 0.0 2e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EAN31812.1 - 1.4e-23 82.8 0.0 5e-23 81.0 0.0 1.9 1 1 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 EAN31812.1 - 3.2e-21 75.4 0.0 6.9e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Motile_Sperm PF00635.26 EAN31813.1 - 1e-23 83.2 0.1 1.9e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain RNA_pol_Rpb6 PF01192.22 EAN31813.1 - 5.2e-16 58.3 0.0 9.1e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 ASH PF15780.5 EAN31813.1 - 0.024 14.9 0.2 0.062 13.5 0.2 1.7 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Rad21_Rec8 PF04824.16 EAN31814.1 - 0.0093 15.2 0.1 0.019 14.2 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein CHIP_TPR_N PF18391.1 EAN31814.1 - 0.052 14.3 0.6 0.18 12.6 0.6 1.9 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain CLP1_P PF16575.5 EAN31815.1 - 5.7e-18 65.4 0.0 1.3e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop TIM PF00121.18 EAN31816.1 - 2.6e-84 282.4 0.0 2.9e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 EAN31816.1 - 0.079 12.4 0.1 0.13 11.7 0.1 1.4 1 1 0 1 1 1 0 CutC family Torus PF16131.5 EAN31817.1 - 6.3e-32 110.5 1.2 1.2e-31 109.6 0.3 1.9 2 0 0 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 EAN31817.1 - 0.0023 17.7 4.8 0.0057 16.4 4.8 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EAN31817.1 - 0.082 13.0 6.8 0.25 11.5 6.8 1.9 1 0 0 1 1 1 0 Zinc finger domain Pox_A22 PF04848.13 EAN31817.1 - 0.09 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A22 protein zf-CCCH PF00642.24 EAN31817.1 - 0.32 11.0 4.8 0.76 9.8 4.8 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GDPD PF03009.17 EAN31819.1 - 0.033 13.9 0.6 0.074 12.8 0.6 1.6 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Prefoldin_2 PF01920.20 EAN31821.1 - 1.6e-16 60.1 2.0 2.1e-16 59.8 2.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EAN31821.1 - 0.00055 19.8 0.6 0.0064 16.4 0.6 2.1 1 1 0 1 1 1 1 Prefoldin subunit Baculo_PEP_C PF04513.12 EAN31821.1 - 0.002 18.2 1.2 0.0039 17.3 1.2 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EAN31821.1 - 0.0032 17.7 0.6 0.62 10.4 0.1 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) CdvA PF18822.1 EAN31821.1 - 0.0049 16.7 0.6 0.0049 16.7 0.6 2.1 2 1 1 3 3 3 1 CdvA-like coiled-coil domain UPF0242 PF06785.11 EAN31821.1 - 0.0096 16.1 2.4 0.24 11.5 0.1 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus DUF4795 PF16043.5 EAN31821.1 - 0.013 15.1 5.2 0.031 13.9 5.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) EMP24_GP25L PF01105.24 EAN31821.1 - 0.014 15.3 0.0 0.018 15.0 0.0 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD THOC7 PF05615.13 EAN31821.1 - 0.014 15.6 1.0 1.9 8.8 0.1 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 TMF_TATA_bd PF12325.8 EAN31821.1 - 0.015 15.5 3.4 0.3 11.3 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CREPT PF16566.5 EAN31821.1 - 0.022 14.9 0.3 0.03 14.5 0.3 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF883 PF05957.13 EAN31821.1 - 0.036 14.7 1.5 0.08 13.5 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Seryl_tRNA_N PF02403.22 EAN31821.1 - 0.04 14.2 1.9 0.41 10.9 0.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.14 EAN31821.1 - 0.042 14.2 0.1 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Phage_GP20 PF06810.11 EAN31821.1 - 0.055 13.3 1.2 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 IL11 PF07400.11 EAN31821.1 - 0.056 13.1 1.0 0.07 12.8 1.0 1.1 1 0 0 1 1 1 0 Interleukin 11 APG6_N PF17675.1 EAN31821.1 - 0.068 13.7 2.3 0.14 12.7 2.3 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region RasGAP_C PF03836.15 EAN31821.1 - 0.13 12.5 2.3 2.4 8.3 0.3 2.2 1 1 0 2 2 2 0 RasGAP C-terminus TMF_DNA_bd PF12329.8 EAN31821.1 - 0.14 12.2 6.4 1.9 8.5 0.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 EAN31821.1 - 0.14 12.2 3.1 0.77 9.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HALZ PF02183.18 EAN31821.1 - 0.14 12.4 3.7 4.4 7.6 0.9 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 EAN31821.1 - 0.15 12.1 7.9 0.24 11.4 1.1 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EAN31821.1 - 0.17 12.0 3.9 0.47 10.5 0.5 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Val_tRNA-synt_C PF10458.9 EAN31821.1 - 0.27 11.5 4.0 7.6 6.9 0.3 2.6 2 2 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm bZIP_1 PF00170.21 EAN31821.1 - 0.31 11.2 5.3 0.97 9.6 0.3 2.9 2 1 1 3 3 3 0 bZIP transcription factor Spc24 PF08286.11 EAN31821.1 - 0.77 10.0 5.6 4.9 7.4 1.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 XhlA PF10779.9 EAN31821.1 - 2.2 8.5 5.1 14 6.0 0.7 2.5 2 1 0 2 2 2 0 Haemolysin XhlA tRNA-synt_2 PF00152.20 EAN31822.1 - 9.3e-50 169.5 0.4 1.3e-49 169.0 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EAN31822.1 - 1.9e-06 27.6 0.0 0.0026 17.3 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 EAN31822.1 - 0.0048 16.8 0.2 0.023 14.6 0.1 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RNA_pol_L_2 PF13656.6 EAN31823.1 - 6.1e-28 96.4 0.0 7.4e-28 96.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EAN31823.1 - 1.6e-07 30.6 0.0 2.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-B_box PF00643.24 EAN31824.1 - 8.7e-11 41.8 17.5 1.2e-05 25.3 4.7 2.4 2 0 0 2 2 2 2 B-box zinc finger DUF3781 PF12636.7 EAN31824.1 - 0.81 9.6 6.0 0.34 10.8 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) Peptidase_M16_C PF05193.21 EAN31825.1 - 7.6e-21 75.0 2.9 3.8e-09 36.8 0.1 5.0 3 2 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EAN31825.1 - 1e-15 58.0 0.6 2.7e-12 46.9 0.2 3.3 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) SHOCT PF09851.9 EAN31825.1 - 7.8 6.4 7.7 0.7 9.7 0.5 3.1 3 0 0 3 3 3 0 Short C-terminal domain HEAT PF02985.22 EAN31826.1 - 7.2e-25 84.9 17.4 0.026 14.8 0.0 11.1 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.6 EAN31826.1 - 6e-15 55.4 0.0 0.0045 17.3 0.0 5.9 4 2 1 5 5 5 4 HEAT repeats Vac14_Fab1_bd PF12755.7 EAN31826.1 - 3.5e-09 37.1 10.9 4e-07 30.5 0.7 4.9 3 1 4 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EAN31826.1 - 1.3e-07 31.8 11.9 0.00095 19.2 1.3 3.8 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EAN31826.1 - 7.5e-06 25.3 5.6 0.71 8.9 0.1 4.7 3 2 1 4 4 4 3 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 EAN31826.1 - 0.0008 19.9 5.3 20 5.8 0.0 6.3 8 0 0 8 8 8 1 HEAT-like repeat ACDC PF14733.6 EAN31826.1 - 0.11 12.8 4.7 2.5 8.5 0.2 4.3 4 0 0 4 4 4 0 AP2-coincident C-terminal RrnaAD PF00398.20 EAN31827.1 - 7.7e-58 195.6 0.0 1.1e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EAN31827.1 - 4.4e-10 40.1 0.0 7.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAN31827.1 - 6.4e-08 32.5 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAN31827.1 - 2.5e-06 28.1 0.0 4.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAN31827.1 - 4e-06 26.3 0.0 6.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EAN31827.1 - 1.3e-05 24.8 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 EAN31827.1 - 0.00041 20.2 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EAN31827.1 - 0.00059 19.6 0.0 0.0009 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EAN31827.1 - 0.0019 18.9 0.0 0.0032 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 EAN31827.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltr_RsmB-F PF01189.17 EAN31827.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F NodS PF05401.11 EAN31827.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) FtsJ PF01728.19 EAN31827.1 - 0.032 14.3 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.12 EAN31827.1 - 0.038 13.1 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase RHD3 PF05879.12 EAN31829.1 - 2.9e-104 349.8 11.8 3.9e-104 349.3 11.8 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 EAN31829.1 - 0.0044 17.1 0.2 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAN31829.1 - 0.011 15.8 0.2 0.036 14.1 0.2 1.9 1 0 0 1 1 1 0 Dynamin family PPDK_N PF01326.19 EAN31829.1 - 0.071 12.4 0.5 0.32 10.2 0.0 2.3 2 1 0 2 2 2 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Peptidase_C14 PF00656.22 EAN31830.1 - 1.2e-24 87.6 0.0 2.2e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Taxilin PF09728.9 EAN31831.1 - 0.0069 15.6 17.6 0.009 15.2 17.6 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Syntaxin-6_N PF09177.11 EAN31831.1 - 0.14 12.8 6.4 0.43 11.2 6.3 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PRD PF00874.20 EAN31831.1 - 0.61 10.4 10.9 4.4 7.7 1.1 2.3 1 1 1 2 2 2 0 PRD domain Csm1_N PF18504.1 EAN31831.1 - 1.4 9.3 10.9 3.2 8.2 6.3 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF4407 PF14362.6 EAN31831.1 - 3.7 6.8 7.7 4.4 6.6 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mit_KHE1 PF10173.9 EAN31831.1 - 4 7.5 9.1 12 5.9 9.0 1.7 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Mt_ATP-synt_D PF05873.12 EAN31831.1 - 8 6.3 16.1 7.4 6.4 4.6 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Rep_2 PF01719.17 EAN31832.1 - 0.0024 17.7 0.5 0.0029 17.4 0.5 1.1 1 0 0 1 1 1 1 Plasmid replication protein Ribosomal_L44 PF00935.19 EAN31833.1 - 7.1e-34 116.1 15.3 1.1e-33 115.5 15.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 ABA_GPCR PF12430.8 EAN31834.1 - 7.1e-16 58.5 13.2 7.1e-16 58.5 13.2 2.4 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor Arm PF00514.23 EAN31835.1 - 0.00014 21.8 0.0 0.0054 16.7 0.1 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat TPR_1 PF00515.28 EAN31835.1 - 0.016 15.0 0.6 1.8 8.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NACHT_N PF17100.5 EAN31835.1 - 0.043 13.7 1.0 0.48 10.2 0.1 2.7 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase UNC45-central PF11701.8 EAN31835.1 - 0.35 10.8 4.3 0.48 10.4 1.4 2.6 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central OHA PF14418.6 EAN31836.1 - 2.8e-23 81.5 0.0 6.8e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 OST-HTH Associated domain DUF3881 PF12997.7 EAN31836.1 - 0.018 14.3 0.2 0.034 13.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) WD40 PF00400.32 EAN31837.1 - 5.3e-33 112.5 18.4 2.3e-07 31.4 0.4 10.9 11 1 0 11 11 11 5 WD domain, G-beta repeat Utp12 PF04003.12 EAN31837.1 - 5.4e-16 58.8 1.6 1.3e-15 57.6 1.6 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EAN31837.1 - 1.8e-11 44.1 3.1 0.49 10.7 0.0 8.4 6 3 2 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAN31837.1 - 4.2e-07 29.3 1.3 0.013 14.5 0.0 5.1 5 1 1 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EAN31837.1 - 2.3e-06 27.7 6.4 0.0077 16.1 0.1 5.5 5 1 2 7 7 7 2 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 EAN31837.1 - 0.00037 19.7 0.4 1.6 7.8 0.1 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1513) Kelch_6 PF13964.6 EAN31837.1 - 0.023 15.0 0.1 1.5 9.2 0.0 3.2 2 0 0 2 2 2 0 Kelch motif Exonuc_VII_S PF02609.16 EAN31838.1 - 0.0064 16.5 3.4 0.0066 16.5 0.4 2.3 2 1 1 3 3 3 1 Exonuclease VII small subunit PFU PF09070.11 EAN31842.1 - 0.0048 17.1 0.0 0.0053 17.0 0.0 1.2 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) DUF150_C PF17384.2 EAN31842.1 - 0.0055 16.8 0.0 0.0076 16.4 0.0 1.2 1 0 0 1 1 1 1 RimP C-terminal SH3 domain SM-ATX PF14438.6 EAN31842.1 - 0.031 14.4 0.5 4.4 7.5 0.1 2.1 2 0 0 2 2 2 0 Ataxin 2 SM domain LSM PF01423.22 EAN31842.1 - 0.033 13.9 0.5 0.093 12.4 0.1 1.9 2 0 0 2 2 2 0 LSM domain NTS PF15447.6 EAN31842.1 - 0.16 12.5 0.1 0.27 11.8 0.1 1.3 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 SprT-like PF10263.9 EAN31843.1 - 3.9e-26 91.1 0.2 6.8e-26 90.4 0.1 1.5 2 0 0 2 2 2 1 SprT-like family Peptidase_M76 PF09768.9 EAN31843.1 - 0.081 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M76 family EF1G PF00647.19 EAN31844.1 - 1.5e-35 121.4 1.1 4e-35 120.1 0.4 2.0 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C_3 PF14497.6 EAN31844.1 - 3.1e-05 24.1 0.8 9.3e-05 22.6 0.2 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAN31844.1 - 0.00011 22.3 0.0 0.00027 21.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L6e PF01159.19 EAN31845.1 - 7.8e-28 97.2 3.8 1.6e-27 96.2 3.8 1.5 1 1 0 1 1 1 1 Ribosomal protein L6e Peptidase_M41 PF01434.18 EAN31846.1 - 1.1e-54 185.2 1.0 1.9e-54 184.4 1.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EAN31846.1 - 2.1e-40 138.2 0.0 9e-40 136.2 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EAN31846.1 - 6.3e-06 25.6 0.2 0.00022 20.6 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_lid_3 PF17862.1 EAN31846.1 - 8.3e-06 25.5 0.2 1.7e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EAN31846.1 - 2.9e-05 24.4 0.6 0.43 10.8 0.0 4.0 2 1 2 4 4 4 2 AAA domain RuvB_N PF05496.12 EAN31846.1 - 0.00045 20.0 0.0 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 EAN31846.1 - 0.0019 17.5 0.1 0.0047 16.2 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EAN31846.1 - 0.0019 18.7 0.2 0.013 16.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EAN31846.1 - 0.0021 18.5 0.2 0.027 14.8 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EAN31846.1 - 0.0044 17.3 0.1 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EAN31846.1 - 0.0091 16.0 0.0 0.06 13.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 EAN31846.1 - 0.013 15.5 0.0 0.078 13.0 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EAN31846.1 - 0.014 15.2 0.2 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 EAN31846.1 - 0.02 14.6 0.0 2.8 7.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 EAN31846.1 - 0.029 14.5 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EAN31846.1 - 0.03 14.5 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EAN31846.1 - 0.036 13.4 0.1 0.073 12.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 EAN31846.1 - 0.047 14.1 0.0 0.5 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EAN31846.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 EAN31846.1 - 0.072 12.9 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.6 EAN31846.1 - 0.093 12.3 0.8 1.7 8.2 0.3 2.3 1 1 1 2 2 2 0 AAA domain Reprolysin_3 PF13582.6 EAN31846.1 - 0.14 12.7 0.2 0.58 10.7 0.0 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like RRM_1 PF00076.22 EAN31847.1 - 0.00021 21.0 0.4 0.46 10.3 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kri1 PF05178.12 EAN31848.1 - 1.9e-13 50.9 5.3 1.9e-13 50.9 5.3 5.1 4 1 1 5 5 5 1 KRI1-like family Kri1_C PF12936.7 EAN31848.1 - 2.7e-12 46.7 3.5 2.7e-12 46.7 3.5 3.8 3 0 0 3 3 3 1 KRI1-like family C-terminal ZZ PF00569.17 EAN31848.1 - 0.00031 20.5 8.3 0.00031 20.5 6.7 1.8 2 0 0 2 2 2 1 Zinc finger, ZZ type C1_2 PF03107.16 EAN31848.1 - 0.0042 17.4 6.3 0.0098 16.2 6.3 1.7 1 0 0 1 1 1 1 C1 domain zf-UBR PF02207.20 EAN31848.1 - 0.19 11.9 7.1 0.36 11.0 7.1 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Pet191_N PF10203.9 EAN31849.1 - 2.6e-17 62.8 6.9 5e-17 62.0 6.9 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EAN31849.1 - 0.23 11.5 6.2 0.46 10.5 1.5 2.3 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EAN31849.1 - 0.28 11.2 7.2 3 7.9 1.5 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TRAP_alpha PF03896.16 EAN31850.1 - 0.0029 16.8 6.1 0.0037 16.5 6.1 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF4834 PF16118.5 EAN31850.1 - 0.003 18.5 0.0 0.0043 18.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) SID-1_RNA_chan PF13965.6 EAN31850.1 - 0.012 14.0 0.4 0.011 14.1 0.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RRN3 PF05327.11 EAN31850.1 - 0.045 12.3 10.1 0.048 12.2 10.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Afi1 PF07792.12 EAN31850.1 - 0.072 13.6 6.3 0.093 13.2 6.3 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking V_ATPase_I PF01496.19 EAN31850.1 - 0.074 11.0 1.7 0.086 10.8 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.7 EAN31850.1 - 0.077 11.1 3.1 0.084 11.0 3.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 EAN31850.1 - 0.095 11.7 1.1 0.093 11.7 1.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Connexin PF00029.19 EAN31850.1 - 0.14 11.9 0.8 0.16 11.7 0.8 1.3 1 0 0 1 1 1 0 Connexin DNA_pol_phi PF04931.13 EAN31850.1 - 0.29 9.2 21.2 0.33 9.0 21.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF4820 PF16091.5 EAN31850.1 - 0.36 10.2 4.4 0.45 9.8 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pannexin_like PF12534.8 EAN31850.1 - 0.4 9.7 2.2 0.48 9.4 2.2 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Nop14 PF04147.12 EAN31850.1 - 0.47 8.6 22.1 0.51 8.5 22.1 1.0 1 0 0 1 1 1 0 Nop14-like family DDRGK PF09756.9 EAN31850.1 - 0.5 9.9 14.0 0.62 9.6 14.0 1.1 1 0 0 1 1 1 0 DDRGK domain CDC45 PF02724.14 EAN31850.1 - 0.87 7.8 15.0 0.89 7.8 15.0 1.0 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 EAN31850.1 - 0.89 9.8 18.1 1.2 9.4 18.1 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RR_TM4-6 PF06459.12 EAN31850.1 - 1.2 8.9 11.6 1.4 8.7 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EAN31850.1 - 2.2 7.0 8.2 2.4 6.8 8.2 1.1 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 EAN31850.1 - 3.1 7.1 23.2 3.5 7.0 23.2 1.0 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 EAN31850.1 - 3.3 7.3 13.6 21 4.8 13.6 2.0 1 1 0 1 1 1 0 FAM176 family CobT PF06213.12 EAN31850.1 - 4.4 6.6 20.0 5.6 6.3 20.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.14 EAN31850.1 - 5 7.5 8.5 6.5 7.2 8.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 EAN31850.1 - 6.2 5.7 6.4 7.2 5.5 6.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Astro_capsid_p PF12226.8 EAN31850.1 - 6.5 5.8 12.1 8 5.5 12.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NPR3 PF03666.13 EAN31850.1 - 7.4 5.2 9.1 8.1 5.1 9.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.15 EAN31850.1 - 8.3 5.1 12.4 9.4 4.9 12.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MDM10 PF12519.8 EAN31850.1 - 9 5.0 8.0 11 4.8 8.0 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF1617 PF07761.12 EAN31851.1 - 0.017 15.2 0.4 0.026 14.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) PH PF00169.29 EAN31851.1 - 0.1 13.1 0.1 0.46 11.0 0.0 2.3 2 1 0 2 2 2 0 PH domain AAA_23 PF13476.6 EAN31852.1 - 3.1e-15 57.2 2.6 3.1e-15 57.2 2.6 5.1 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 EAN31852.1 - 0.00059 19.5 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EAN31852.1 - 0.0044 16.5 53.8 0.053 12.9 53.8 3.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAN31852.1 - 0.0067 16.3 1.9 0.0067 16.3 1.9 3.6 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Vac_Fusion PF02346.16 EAN31852.1 - 0.094 12.4 4.2 0.16 11.6 0.2 3.4 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DEAD PF00270.29 EAN31853.1 - 2.2e-20 73.1 0.0 4.1e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN31853.1 - 8.6e-20 71.2 0.0 6.6e-17 61.9 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.10 EAN31853.1 - 1.6e-16 60.1 0.0 3.7e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 EAN31853.1 - 1.6e-10 41.5 6.8 1.6e-10 41.5 6.8 2.5 3 0 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 EAN31853.1 - 3.6e-10 40.1 0.0 1e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit V-ATPase_G_2 PF16999.5 EAN31855.1 - 0.24 11.8 5.2 0.6 10.6 5.2 1.6 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Chal_sti_synt_N PF00195.19 EAN31855.1 - 0.81 9.1 4.8 2 7.7 0.9 2.3 2 0 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Cytochrom_C_2 PF01322.20 EAN31855.1 - 1.8 9.5 8.8 1.2 10.1 3.7 2.6 1 1 1 2 2 2 0 Cytochrome C' Thymidylat_synt PF00303.19 EAN31856.1 - 1.7e-111 371.6 0.0 2.3e-111 371.2 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 EAN31856.1 - 1.4e-22 80.1 0.0 1.1e-21 77.2 0.0 2.4 1 1 0 1 1 1 1 Dihydrofolate reductase LapA_dom PF06305.11 EAN31857.1 - 0.0034 17.2 0.1 0.0046 16.7 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Peptidase_M48_N PF16491.5 EAN31857.1 - 0.041 13.8 0.1 0.056 13.3 0.1 1.2 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices SieB PF14163.6 EAN31857.1 - 0.043 13.3 1.4 0.049 13.1 0.8 1.4 1 1 0 1 1 1 0 Super-infection exclusion protein B FeoB_associated PF12669.7 EAN31857.1 - 0.11 12.9 2.3 0.14 12.6 2.3 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Pkinase PF00069.25 EAN31858.1 - 1.3e-35 123.0 2.9 3.6e-35 121.6 0.5 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN31858.1 - 3.5e-28 98.6 0.4 1.6e-27 96.4 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Myb_DNA-binding PF00249.31 EAN31859.1 - 2.7e-10 40.3 1.3 0.0007 19.7 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAN31859.1 - 3.2e-05 24.1 2.9 0.05 13.9 0.1 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Hat1_N PF10394.9 EAN31860.1 - 1.4e-07 31.9 5.6 0.00017 21.9 5.6 2.9 1 1 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 EAN31860.1 - 0.047 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MCM PF00493.23 EAN31862.1 - 7.4e-43 146.2 0.2 1.3e-42 145.5 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EAN31862.1 - 7.4e-15 55.2 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EAN31862.1 - 2.2e-05 24.0 0.0 0.00096 18.6 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EAN31862.1 - 0.0089 16.4 0.1 0.017 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EAN31862.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM_OB PF17207.3 EAN31862.1 - 0.033 14.0 0.3 0.079 12.8 0.3 1.6 1 0 0 1 1 1 0 MCM OB domain RuvB_N PF05496.12 EAN31862.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RAP PF08373.10 EAN31864.1 - 1.9e-15 56.7 1.0 4.8e-15 55.4 1.0 1.7 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 EAN31864.1 - 0.012 15.7 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 REase_MTES_1575 DUF4368 PF14287.6 EAN31864.1 - 0.014 15.7 0.8 5.3 7.4 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4368) Ribosomal_L37 PF08561.10 EAN31865.1 - 5e-06 27.0 3.6 0.00032 21.2 2.6 2.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 GTP_EFTU PF00009.27 EAN31866.1 - 3.1e-44 150.8 0.0 3.6e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EAN31866.1 - 4.8e-22 78.4 0.0 2e-21 76.4 0.0 2.1 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EAN31866.1 - 2.7e-08 34.1 0.2 7.9e-08 32.6 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAN31866.1 - 0.0026 17.8 0.1 0.015 15.4 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.15 EAN31866.1 - 0.0031 17.1 0.3 0.0031 17.1 0.3 2.0 2 0 0 2 2 2 1 Ataxin-2 C-terminal region zf-C3HC4_2 PF13923.6 EAN31867.1 - 9.7e-12 44.5 10.9 2e-11 43.5 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAN31867.1 - 1.3e-08 34.6 12.1 2.8e-08 33.5 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAN31867.1 - 5e-08 32.7 6.7 8.8e-08 31.9 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAN31867.1 - 6.1e-08 32.9 10.7 6.1e-08 32.9 10.7 1.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EAN31867.1 - 1.3e-07 31.5 7.0 1.3e-07 31.5 7.0 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EAN31867.1 - 1.9e-07 31.1 12.7 4.8e-07 29.8 12.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EAN31867.1 - 1.1e-06 28.5 10.2 2.3e-06 27.5 10.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 EAN31867.1 - 1.4e-06 28.3 3.3 4.1e-06 26.8 3.3 1.8 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 EAN31867.1 - 5.5e-06 26.5 0.1 1e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 EAN31867.1 - 0.0011 18.7 13.7 0.0087 15.9 14.0 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EAN31867.1 - 0.0012 19.1 11.4 0.004 17.4 11.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EAN31867.1 - 0.0028 17.5 5.0 0.0055 16.6 5.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF1796 PF08795.10 EAN31867.1 - 0.025 14.5 0.9 0.04 13.9 0.3 1.6 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) zf-RING_4 PF14570.6 EAN31867.1 - 0.052 13.3 9.5 0.27 11.1 9.7 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EAN31867.1 - 0.11 12.3 9.4 0.23 11.3 9.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit LRR_4 PF12799.7 EAN31869.1 - 1.4e-09 38.0 15.2 0.0039 17.6 0.4 5.6 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAN31869.1 - 0.0029 17.3 10.4 3.4 7.5 0.3 5.1 3 2 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 EAN31869.1 - 0.0046 17.3 18.7 8.9 7.3 0.8 6.7 6 1 0 6 6 6 3 Leucine Rich Repeat DUF3770 PF12603.8 EAN31869.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) F-box-like PF12937.7 EAN31869.1 - 0.22 11.4 1.7 0.45 10.4 0.3 2.3 2 0 0 2 2 2 0 F-box-like Pkinase PF00069.25 EAN31870.1 - 1.7e-73 247.2 0.1 3.7e-73 246.1 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN31870.1 - 4.4e-39 134.3 0.0 7.5e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EAN31870.1 - 1.2e-11 45.1 0.1 1.2e-11 45.1 0.1 3.0 2 1 1 3 3 3 1 PH domain Kinase-like PF14531.6 EAN31870.1 - 1.6e-06 27.7 0.0 5.5e-06 25.9 0.0 1.9 1 1 0 2 2 2 1 Kinase-like EF-hand_6 PF13405.6 EAN31870.1 - 1.4e-05 24.7 11.5 0.0018 18.1 0.2 4.9 4 0 0 4 4 3 2 EF-hand domain RIO1 PF01163.22 EAN31870.1 - 5.1e-05 23.0 0.4 0.00016 21.3 0.4 1.8 1 0 0 1 1 1 1 RIO1 family EF-hand_8 PF13833.6 EAN31870.1 - 5.4e-05 23.0 6.4 0.0049 16.7 0.3 3.9 2 1 1 3 3 3 1 EF-hand domain pair Kdo PF06293.14 EAN31870.1 - 6.2e-05 22.4 0.1 0.00014 21.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_1 PF00036.32 EAN31870.1 - 8.7e-05 21.8 14.7 0.064 12.8 0.7 4.8 4 0 0 4 4 3 2 EF hand EF-hand_7 PF13499.6 EAN31870.1 - 0.00029 21.2 7.8 0.0055 17.1 0.8 4.8 3 1 2 5 5 5 3 EF-hand domain pair FTA2 PF13095.6 EAN31870.1 - 0.0045 16.6 0.2 0.21 11.2 0.0 2.5 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAN31870.1 - 0.013 15.5 0.0 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAN31870.1 - 0.017 14.0 0.0 0.017 14.0 0.0 2.7 4 0 0 4 4 4 0 Fungal protein kinase EF-hand_5 PF13202.6 EAN31870.1 - 0.34 10.5 8.4 1.4 8.6 0.1 3.3 3 0 0 3 3 2 0 EF hand zf-UBR PF02207.20 EAN31871.1 - 8.4e-10 38.7 15.5 8.4e-10 38.7 15.5 3.1 2 2 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_5 PF14634.6 EAN31871.1 - 0.0018 18.2 3.9 0.0018 18.2 3.9 3.5 4 0 0 4 4 4 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 EAN31871.1 - 0.013 15.7 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 EAN31871.1 - 0.03 14.7 1.1 0.03 14.7 1.1 3.9 3 1 0 3 3 3 0 Ring finger domain Ku_PK_bind PF08785.11 EAN31871.1 - 0.056 13.6 0.6 0.2 11.8 0.2 2.2 2 0 0 2 2 2 0 Ku C terminal domain like zf-RING_UBOX PF13445.6 EAN31871.1 - 3.4 7.8 11.9 0.096 12.7 0.5 4.0 3 1 1 4 4 4 0 RING-type zinc-finger zf-RING_11 PF17123.5 EAN31871.1 - 7.4 6.4 9.1 3 7.7 0.2 3.5 3 0 0 3 3 3 0 RING-like zinc finger SRP1_TIP1 PF00660.17 EAN31872.1 - 0.024 14.7 0.9 3.7 7.7 0.1 2.9 2 0 0 2 2 2 0 Seripauperin and TIP1 family zf-UBP PF02148.19 EAN31872.1 - 0.29 11.5 7.2 2 8.8 4.7 2.9 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Usher PF00577.20 EAN31874.1 - 0.052 12.4 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Outer membrane usher protein Spc42p PF11544.8 EAN31876.1 - 0.058 13.4 0.3 0.28 11.2 0.3 2.2 1 0 0 1 1 1 0 Spindle pole body component Spc42p Syntaxin_2 PF14523.6 EAN31876.1 - 0.39 11.1 6.6 0.63 10.4 2.6 2.6 2 0 0 2 2 2 0 Syntaxin-like protein Mannosyl_trans PF05007.13 EAN31877.1 - 2.8e-54 184.7 31.6 4.4e-54 184.1 31.6 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) GT87 PF09594.10 EAN31877.1 - 2.8e-05 23.9 2.9 2.8e-05 23.9 2.9 2.4 1 1 0 2 2 2 1 Glycosyltransferase family 87 PIG-U PF06728.13 EAN31877.1 - 0.00041 19.5 45.5 0.00063 18.9 45.5 1.3 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U UPF1_Zn_bind PF09416.10 EAN31878.1 - 0.012 15.6 0.1 2.6 8.0 0.2 2.2 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) TIR_3 PF18567.1 EAN31879.1 - 0.051 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain Kelch_3 PF13415.6 EAN31880.1 - 6.7e-18 64.5 8.9 2.3e-08 34.1 0.1 6.1 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EAN31880.1 - 9.8e-11 41.4 14.4 7.5e-05 22.6 0.1 6.2 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EAN31880.1 - 8.5e-10 38.1 0.4 2.5e-06 27.0 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 EAN31880.1 - 1.9e-07 31.0 17.4 2.1e-06 27.6 0.9 6.0 5 2 1 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EAN31880.1 - 3e-06 27.3 8.1 0.0032 17.7 0.1 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 EAN31880.1 - 0.0024 17.8 12.0 0.027 14.5 0.2 4.4 6 0 0 6 6 6 2 Kelch motif TFIIS_C PF01096.18 EAN31881.1 - 1.8e-19 69.3 2.9 1.8e-19 69.3 2.9 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 EAN31881.1 - 7.5e-05 22.6 6.3 0.00046 20.1 0.2 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EAN31881.1 - 0.0004 20.2 2.0 0.0004 20.2 2.0 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 EAN31881.1 - 0.031 13.8 0.8 0.031 13.8 0.8 3.1 2 1 0 2 2 2 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 EAN31881.1 - 0.063 13.2 5.5 0.67 10.0 0.1 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DUF2387 PF09526.10 EAN31881.1 - 0.47 10.6 6.0 1.7 8.8 0.6 2.3 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf_C2H2_10 PF18414.1 EAN31881.1 - 0.66 9.6 5.4 3.1 7.4 0.0 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger zf-Mss51 PF13824.6 EAN31881.1 - 1.1 9.4 9.3 1.6 8.9 2.4 2.6 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Tnp_zf-ribbon_2 PF13842.6 EAN31881.1 - 2.1 9.3 8.9 0.77 10.6 1.0 3.0 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon zf-RRN7 PF11781.8 EAN31881.1 - 3.2 7.5 6.8 7.9 6.3 0.1 3.4 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Nudix_N_2 PF14803.6 EAN31881.1 - 4.7 7.2 9.5 26 4.9 0.1 3.7 4 0 0 4 4 4 0 Nudix N-terminal zf-Dof PF02701.15 EAN31881.1 - 5.3 7.3 10.0 0.21 11.8 0.9 2.4 2 1 0 2 2 2 0 Dof domain, zinc finger XPG_I PF00867.18 EAN31882.1 - 1.5e-26 92.5 0.0 4.8e-26 90.9 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EAN31882.1 - 1.4e-17 64.0 0.0 7e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 EAN31882.1 - 0.00023 20.7 0.1 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.20 EAN31882.1 - 0.0058 17.2 0.0 0.025 15.2 0.0 2.1 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold zf-Tim10_DDP PF02953.15 EAN31883.1 - 6.7e-12 44.9 2.0 8e-12 44.6 2.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CDtoxinA PF03498.14 EAN31883.1 - 0.013 15.1 1.0 0.014 15.0 1.0 1.1 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain EF-hand_7 PF13499.6 EAN31884.1 - 0.0003 21.2 0.1 0.00073 19.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 EAN31884.1 - 0.023 15.0 0.0 0.46 10.8 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain EF-hand_6 PF13405.6 EAN31884.1 - 0.04 13.9 0.3 1.1 9.3 0.0 3.2 3 1 1 4 4 4 0 EF-hand domain EF-hand_1 PF00036.32 EAN31884.1 - 0.057 13.0 0.1 6.4 6.6 0.0 3.1 3 0 0 3 3 3 0 EF hand Lsm_interact PF05391.11 EAN31884.1 - 2.7 7.6 5.5 6.1 6.5 5.5 1.5 1 0 0 1 1 1 0 Lsm interaction motif YabA PF06156.13 EAN31885.1 - 0.0016 19.1 0.1 0.54 10.9 0.0 2.5 1 1 1 2 2 2 2 Initiation control protein YabA zf-C2H2_jaz PF12171.8 EAN31886.1 - 6.1e-08 32.7 2.6 1.3e-07 31.7 2.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EAN31886.1 - 0.00057 20.2 1.5 0.001 19.4 1.5 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) CENP-B_dimeris PF09026.10 EAN31886.1 - 0.0024 18.2 1.6 0.0033 17.8 1.6 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain AKAP95 PF04988.12 EAN31886.1 - 0.0053 17.0 4.2 0.0071 16.6 4.2 1.2 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) DUF1676 PF07898.13 EAN31886.1 - 0.034 14.2 3.2 0.041 13.9 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF2052 PF09747.9 EAN31886.1 - 0.035 14.2 5.3 0.044 13.9 5.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RRN3 PF05327.11 EAN31886.1 - 0.11 11.0 4.0 0.14 10.7 4.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 EAN31886.1 - 1.5 7.5 4.2 1.5 7.5 4.2 1.0 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 EAN31886.1 - 3.2 7.4 10.7 10 5.8 10.7 1.7 1 1 0 1 1 1 0 FAM176 family SURF1 PF02104.15 EAN31889.1 - 9.6e-31 107.4 0.0 1.4e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 SURF1 family zf-RING_5 PF14634.6 EAN31890.1 - 8.1e-08 32.1 8.2 1.7e-07 31.1 8.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EAN31890.1 - 1.7e-07 31.4 8.9 6.8e-07 29.5 8.9 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EAN31890.1 - 1.9e-07 31.0 7.6 2.2e-07 30.8 1.6 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAN31890.1 - 1.6e-06 27.9 10.3 2.7e-05 23.9 10.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAN31890.1 - 6.9e-06 25.8 5.4 2.8e-05 23.9 5.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAN31890.1 - 9.2e-06 25.4 7.8 0.00015 21.5 5.0 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EAN31890.1 - 0.00028 20.7 10.4 0.00036 20.3 4.6 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAN31890.1 - 0.00092 19.5 6.2 0.0024 18.1 5.6 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EAN31890.1 - 0.014 15.1 9.0 0.58 9.9 3.8 3.3 2 1 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EAN31890.1 - 0.023 14.9 9.0 0.028 14.6 5.1 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4121 PF13497.6 EAN31890.1 - 0.028 13.6 0.1 0.047 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) zf-RING_4 PF14570.6 EAN31890.1 - 0.033 14.0 6.8 0.2 11.5 7.1 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 EAN31890.1 - 0.19 12.0 6.4 0.75 10.1 6.4 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Lar_restr_allev PF14354.6 EAN31890.1 - 0.21 12.0 4.1 0.66 10.4 4.1 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar DPM3 PF08285.11 EAN31891.1 - 7.2e-07 29.3 0.4 8.1e-07 29.2 0.4 1.1 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4131 PF13567.6 EAN31891.1 - 0.036 13.7 0.7 0.038 13.6 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3989 PF13150.6 EAN31891.1 - 0.12 12.1 0.5 0.21 11.4 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3989) RRM_1 PF00076.22 EAN31892.1 - 3.3e-38 129.4 0.2 1.7e-19 69.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAN31892.1 - 0.00011 22.1 0.0 0.17 11.9 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 EAN31892.1 - 0.00043 20.2 0.0 4.9 7.2 0.0 3.4 3 0 0 3 3 3 2 DbpA RNA binding domain RRM_occluded PF16842.5 EAN31892.1 - 0.0079 16.0 0.0 4.5 7.2 0.0 3.3 3 1 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EAN31892.1 - 0.016 15.3 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif CAS_CSE1 PF03378.15 EAN31893.1 - 8.9e-46 156.3 7.6 2.2e-45 155.0 7.6 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EAN31893.1 - 6.7e-45 153.5 11.3 6.7e-45 153.5 11.3 2.1 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.19 EAN31893.1 - 0.00023 21.0 2.5 0.0089 15.9 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arf PF00025.21 EAN31894.1 - 1.4e-58 197.2 0.0 1.6e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAN31894.1 - 3.4e-09 36.8 0.0 4.8e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EAN31894.1 - 3.5e-09 36.9 0.0 9.6e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EAN31894.1 - 3.8e-09 36.2 0.1 1.5e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EAN31894.1 - 9.2e-09 35.0 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EAN31894.1 - 7.1e-08 32.2 0.0 2.8e-07 30.3 0.0 1.7 1 1 1 2 2 2 1 Ras family GTP_EFTU PF00009.27 EAN31894.1 - 2.8e-05 23.8 0.0 0.00055 19.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAN31894.1 - 0.00021 20.8 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAN31894.1 - 0.011 15.6 0.0 1.6 8.6 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase cobW PF02492.19 EAN31894.1 - 0.016 14.8 0.2 2.4 7.7 0.0 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EAN31894.1 - 0.078 13.3 0.0 0.17 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EAN31894.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Maf1 PF09174.10 EAN31897.1 - 1.3e-19 71.0 7.0 2.2e-19 70.3 7.0 1.4 1 1 0 1 1 1 1 Maf1 regulator DUF4802 PF16060.5 EAN31897.1 - 0.015 15.4 0.1 0.015 15.4 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4802) Band_7 PF01145.25 EAN31898.1 - 0.00018 21.5 0.1 0.00023 21.2 0.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family TAD2 PF18521.1 EAN31898.1 - 0.015 15.2 0.4 0.035 14.0 0.4 1.5 1 0 0 1 1 1 0 Transactivation domain 2 IF2_N PF04760.15 EAN31898.1 - 0.16 11.8 1.7 1.9 8.4 0.2 2.6 2 1 1 3 3 3 0 Translation initiation factor IF-2, N-terminal region zf-CDGSH PF09360.10 EAN31899.1 - 3.9e-08 33.4 0.2 5.7e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type CRAL_TRIO PF00650.20 EAN31900.1 - 2e-24 86.2 0.0 4e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EAN31900.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAN31900.1 - 0.055 13.7 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain LETM1 PF07766.13 EAN31901.1 - 2.3e-82 276.3 14.0 2.3e-82 276.3 14.0 2.4 2 1 0 2 2 2 1 LETM1-like protein SpoU_sub_bind PF08032.12 EAN31901.1 - 1.6 9.1 4.1 0.64 10.3 0.5 2.3 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Memo PF01875.17 EAN31902.1 - 3e-79 266.0 0.0 3.4e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein T7SS_ESX_EspC PF10824.8 EAN31902.1 - 0.00083 19.8 0.9 0.0019 18.6 0.4 1.8 2 0 0 2 2 2 1 Excreted virulence factor EspC, type VII ESX diderm Pkinase PF00069.25 EAN31903.1 - 1.2e-70 237.9 0.0 2e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN31903.1 - 2.1e-36 125.5 0.0 4.2e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAN31903.1 - 1.5e-05 24.2 2.6 2.6e-05 23.4 2.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAN31903.1 - 4.8e-05 22.8 0.0 8.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EAN31903.1 - 0.0017 18.0 0.2 0.003 17.2 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EAN31903.1 - 0.0053 16.1 0.3 0.0078 15.6 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAN31903.1 - 0.2 11.6 0.0 0.39 10.6 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mito_carr PF00153.27 EAN31904.1 - 5.8e-42 141.5 1.8 1.2e-15 57.1 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein BTB_2 PF02214.22 EAN31905.1 - 3e-15 56.3 0.7 2.9e-14 53.2 0.7 2.3 1 1 0 1 1 1 1 BTB/POZ domain Cse1 PF08506.10 EAN31906.1 - 0.0014 17.5 0.3 0.0016 17.4 0.3 1.1 1 0 0 1 1 1 1 Cse1 CO_dh PF02552.16 EAN31906.1 - 0.021 14.6 0.7 0.57 9.9 0.0 2.0 1 1 1 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit bZIP_1 PF00170.21 EAN31906.1 - 0.044 13.9 2.4 0.08 13.0 0.5 2.1 2 1 0 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 EAN31906.1 - 0.076 13.3 0.5 0.17 12.2 0.5 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family YedD PF13987.6 EAN31906.1 - 0.091 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 YedD-like protein Shugoshin_N PF07558.11 EAN31906.1 - 0.1 12.5 1.8 0.21 11.5 0.5 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 EAN31906.1 - 0.16 12.6 2.9 0.29 11.8 2.0 1.7 1 1 1 2 2 2 0 Initiation control protein YabA zf-RING_2 PF13639.6 EAN31907.1 - 1.1e-10 41.6 4.5 1.6e-10 41.1 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 EAN31907.1 - 2.6e-08 33.4 2.0 6.1e-08 32.2 2.0 1.6 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EAN31907.1 - 1.1e-07 31.6 3.8 1.9e-07 30.8 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAN31907.1 - 1.8e-07 30.9 2.2 2.5e-07 30.4 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN31907.1 - 3.6e-07 30.1 1.4 3.6e-07 30.1 1.4 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EAN31907.1 - 5.2e-07 29.9 4.7 1.4e-06 28.5 4.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAN31907.1 - 6e-07 29.2 4.1 1e-06 28.5 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAN31907.1 - 7.1e-06 25.7 1.2 1.9e-05 24.3 1.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EAN31907.1 - 8.4e-06 25.8 0.5 1.3e-05 25.2 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EAN31907.1 - 9.9e-06 25.3 3.0 2.5e-05 24.1 3.1 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EAN31907.1 - 1.9e-05 24.5 2.9 2.9e-05 23.9 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain RINGv PF12906.7 EAN31907.1 - 0.0015 18.6 1.1 0.0036 17.4 1.1 1.7 1 1 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 EAN31907.1 - 0.0016 18.6 6.3 0.016 15.3 6.3 2.4 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_6 PF14835.6 EAN31907.1 - 0.0039 17.0 1.1 0.0066 16.3 1.1 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_1 PF14446.6 EAN31907.1 - 0.0096 15.8 2.1 0.044 13.7 0.2 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 EAN31907.1 - 0.012 15.8 4.3 0.022 14.9 4.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 EAN31907.1 - 0.019 15.3 1.7 0.034 14.4 1.7 1.5 1 1 0 1 1 1 0 RING-like domain PHD PF00628.29 EAN31907.1 - 0.034 14.0 2.1 0.068 13.1 2.1 1.6 1 0 0 1 1 1 0 PHD-finger Rtf2 PF04641.12 EAN31907.1 - 0.039 13.3 0.1 0.046 13.1 0.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_4 PF14570.6 EAN31907.1 - 0.095 12.5 4.7 2.4 8.0 0.3 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 EAN31907.1 - 0.26 11.2 4.5 0.25 11.3 3.3 1.5 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) TH1 PF04858.13 EAN31908.1 - 4.6e-11 42.1 4.9 3.3e-07 29.3 0.8 3.3 3 0 0 3 3 3 3 TH1 protein FH2 PF02181.23 EAN31909.1 - 5.4e-65 219.9 1.8 5.4e-65 219.9 1.8 2.9 3 0 0 3 3 3 1 Formin Homology 2 Domain TPR_12 PF13424.6 EAN31909.1 - 1.1e-09 38.5 0.0 0.00027 21.2 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAN31909.1 - 5e-05 22.9 3.2 0.00026 20.6 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAN31909.1 - 7.5e-05 22.5 0.0 0.0099 15.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAN31909.1 - 0.093 12.9 5.1 0.36 11.1 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAN31909.1 - 0.23 11.8 0.8 32 5.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3987 PF13148.6 EAN31909.1 - 10 5.0 6.2 24 3.8 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CPW_WPC PF09717.10 EAN31910.1 - 1.7e-23 83.3 25.2 7.5e-14 52.4 7.1 2.2 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) SGS PF05002.15 EAN31911.1 - 3e-16 59.3 2.2 3.5e-16 59.1 2.2 1.2 1 0 0 1 1 1 1 SGS domain Carbpep_Y_N PF05388.11 EAN31911.1 - 0.03 14.8 0.6 0.037 14.6 0.6 1.2 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Fijivirus_P9-2 PF06837.11 EAN31911.1 - 0.09 12.2 0.9 0.1 12.0 0.9 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein Met_asp_mut_E PF06368.11 EAN31911.1 - 0.094 11.2 0.2 0.11 11.0 0.2 1.0 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) partial_CstF PF15861.5 EAN31912.1 - 9.6e-28 95.8 0.1 1.9e-27 94.8 0.1 1.5 1 0 0 1 1 1 1 Partial cleavage stimulation factor domain CSTF2_hinge PF14327.6 EAN31912.1 - 4.8e-15 55.8 0.1 4.8e-15 55.8 0.1 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Endostatin PF06482.11 EAN31912.1 - 0.57 9.6 6.6 0.89 9.0 6.6 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin FAM76 PF16046.5 EAN31912.1 - 1.3 8.3 7.5 1.9 7.8 7.5 1.2 1 0 0 1 1 1 0 FAM76 protein Zip PF02535.22 EAN31912.1 - 1.6 7.9 8.7 2 7.6 8.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.9 EAN31912.1 - 4.6 5.4 18.2 5.8 5.0 18.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3306 PF11748.8 EAN31912.1 - 5.1 8.0 8.2 12 6.8 8.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) Peptidase_M17 PF00883.21 EAN31913.1 - 1.6e-97 326.6 0.0 2.2e-97 326.1 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EAN31913.1 - 0.014 15.2 0.1 0.034 14.0 0.0 1.7 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DEAD PF00270.29 EAN31914.1 - 9.9e-48 162.2 0.0 1.6e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN31914.1 - 2.5e-31 108.3 0.0 8.6e-31 106.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN31914.1 - 0.00057 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAN31914.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HABP4_PAI-RBP1 PF04774.15 EAN31915.1 - 9.1e-18 65.2 4.3 1.8e-17 64.2 4.3 1.5 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family SPOC PF07744.13 EAN31917.1 - 2e-12 47.3 0.0 3.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 SPOC domain MTS PF05175.14 EAN31918.1 - 1.3e-08 34.6 0.0 2.5e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EAN31918.1 - 0.0032 17.3 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAN31918.1 - 0.026 15.3 0.0 0.044 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EAN31918.1 - 0.13 13.0 0.0 0.22 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 EAN31918.1 - 0.14 13.2 0.0 0.2 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EAN31918.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Sybindin PF04099.12 EAN31920.1 - 6.4e-33 113.7 0.3 7.3e-33 113.5 0.3 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EAN31920.1 - 0.00058 20.0 0.0 0.00077 19.6 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Spec3 PF15795.5 EAN31922.1 - 4.6e-05 23.9 16.9 0.0036 17.8 9.7 2.1 1 1 1 2 2 2 2 Ectodermal ciliogenesis protein PI3_PI4_kinase PF00454.27 EAN31923.1 - 6.7e-44 150.6 0.0 1.1e-43 149.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase tRNA-synt_1 PF00133.22 EAN31924.1 - 2.5e-44 151.5 3.1 5.7e-17 61.2 0.2 3.5 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EAN31924.1 - 1.7e-08 33.6 4.8 0.0012 17.6 0.0 4.4 3 2 1 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EAN31924.1 - 6.9e-07 29.3 0.2 1.6e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EAN31924.1 - 3.9e-05 23.1 0.1 0.2 11.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-HC5HC2H_2 PF13832.6 EAN31925.1 - 7.8e-30 103.3 80.1 2e-21 76.2 11.1 7.6 5 2 1 6 6 6 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EAN31925.1 - 2.6e-16 59.6 28.4 8.8e-11 41.9 6.6 9.1 4 3 5 9 9 9 4 PHD-like zinc-binding domain PHD_2 PF13831.6 EAN31925.1 - 1.3e-08 34.2 20.9 8.6e-06 25.2 6.5 6.6 6 1 0 6 6 6 2 PHD-finger PHD PF00628.29 EAN31925.1 - 0.00067 19.5 9.0 0.00067 19.5 9.0 9.8 9 2 0 9 9 9 2 PHD-finger HAP2-GCS1 PF10699.9 EAN31926.1 - 3.2e-18 65.4 0.1 7.8e-18 64.2 0.1 1.7 1 0 0 1 1 1 1 Male gamete fusion factor Ras PF00071.22 EAN31927.1 - 2.4e-42 144.3 0.2 3.1e-31 108.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EAN31927.1 - 4.7e-30 104.3 1.3 1.9e-18 66.8 0.2 3.0 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAN31927.1 - 7.5e-10 38.5 0.0 3.8e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAN31927.1 - 5.9e-07 29.2 0.5 1.1e-06 28.4 0.2 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAN31927.1 - 0.0082 16.1 1.6 1 9.3 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 EAN31927.1 - 0.075 13.6 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EAN31927.1 - 0.096 12.8 2.4 0.61 10.2 2.3 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Aminotran_1_2 PF00155.21 EAN31928.1 - 0.072 12.2 1.0 0.093 11.9 0.1 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II Cyclin_N PF00134.23 EAN31929.1 - 2.7e-10 40.1 1.1 6.6e-10 38.8 1.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EAN31929.1 - 0.0025 18.2 1.8 0.15 12.5 0.3 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Pox_F15 PF04596.12 EAN31929.1 - 0.031 14.1 2.3 0.44 10.3 2.3 2.4 1 1 0 1 1 1 0 Poxvirus protein F15 DUF2009 PF09418.10 EAN31930.1 - 6.2e-175 582.6 13.5 1.5e-112 377.0 3.4 3.0 1 1 0 2 2 2 2 Protein of unknown function (DUF2009) Ras_bdg_2 PF14847.6 EAN31930.1 - 0.046 14.1 0.3 0.38 11.1 0.0 2.6 4 0 0 4 4 4 0 Ras-binding domain of Byr2 DUF155 PF02582.14 EAN31930.1 - 0.08 13.0 0.4 0.2 11.7 0.4 1.7 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 CAF1 PF04857.20 EAN31932.1 - 2e-19 69.9 4.5 1.6e-10 40.7 0.0 2.8 1 1 1 3 3 3 2 CAF1 family ribonuclease S1 PF00575.23 EAN31939.1 - 0.0073 16.6 0.6 17 5.8 0.0 4.2 5 0 0 5 5 5 2 S1 RNA binding domain P4Ha_N PF08336.11 EAN31939.1 - 0.091 12.8 5.6 0.13 12.3 0.0 3.3 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region UPF0004 PF00919.20 EAN31940.1 - 9.3e-19 67.3 0.0 2.4e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 EAN31940.1 - 1.9e-17 64.1 0.9 4.7e-17 62.9 0.9 1.7 1 0 0 1 1 1 1 Radical SAM superfamily ECM11 PF15463.6 EAN31942.1 - 0.29 11.7 4.8 41 4.8 4.7 3.1 2 1 1 3 3 3 0 Extracellular mutant protein 11 tRNA-synt_1 PF00133.22 EAN31944.1 - 1.6e-41 142.2 4.6 2.2e-15 55.9 0.4 4.5 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EAN31944.1 - 5.4e-18 64.9 3.0 4.1e-08 32.4 0.1 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EAN31944.1 - 4.6e-12 46.1 3.0 1.3e-11 44.7 3.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EAN31944.1 - 3.5e-10 39.7 0.2 1.4e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EAN31944.1 - 0.36 9.7 4.8 0.39 9.6 0.1 3.1 3 1 1 4 4 4 0 tRNA synthetases class I (K) Mito_carr PF00153.27 EAN31945.1 - 1.6e-15 56.7 0.2 2.6e-07 30.5 0.1 2.2 1 1 1 2 2 2 2 Mitochondrial carrier protein Cullin PF00888.22 EAN31946.1 - 1e-39 136.7 37.0 1.4e-38 133.0 37.0 2.2 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EAN31946.1 - 4e-06 26.8 0.1 2.8e-05 24.0 0.1 2.5 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF5617 PF18493.1 EAN31946.1 - 0.1 12.7 2.6 0.42 10.7 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5617) Band_7 PF01145.25 EAN31946.1 - 0.9 9.5 2.8 2.2 8.2 2.1 1.9 1 1 0 1 1 1 0 SPFH domain / Band 7 family BLM10_mid PF16507.5 EAN31947.1 - 2.3e-22 79.3 17.1 4.6e-21 75.1 17.1 2.4 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EAN31947.1 - 0.067 13.1 0.1 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Fe-S_biosyn PF01521.20 EAN31949.1 - 5.5e-09 36.2 0.0 0.00015 22.0 0.0 2.0 1 1 1 2 2 2 2 Iron-sulphur cluster biosynthesis Peptidase_C1 PF00112.23 EAN31950.1 - 3.7e-15 56.6 1.2 8.4e-15 55.4 1.2 1.6 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EAN31950.1 - 0.0014 17.5 0.2 0.0022 16.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase C1-like family Tox-REase-5 PF15648.6 EAN31950.1 - 0.013 16.0 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 DUF3385 PF11865.8 EAN31952.1 - 0.7 9.8 9.4 5.3 6.9 4.1 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) UCR_UQCRX_QCR9 PF05365.12 EAN31953.1 - 3.4e-09 36.5 0.0 7.5e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF5381 PF17353.2 EAN31953.1 - 0.035 13.8 0.1 0.16 11.7 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5381) AP2 PF00847.20 EAN31954.1 - 3.8e-08 33.5 3.3 3.8e-08 33.5 3.3 1.7 2 0 0 2 2 2 1 AP2 domain XRN1_D1 PF18332.1 EAN31954.1 - 0.19 11.5 1.9 0.39 10.4 1.9 1.5 1 0 0 1 1 1 0 Exoribonuclease Xrn1 D1 domain RNase_PH PF01138.21 EAN31955.1 - 0.0022 18.5 0.0 0.0044 17.5 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 mRNA_triPase PF02940.15 EAN31955.1 - 0.029 14.1 0.1 0.057 13.1 0.1 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain RNase_PH_C PF03725.15 EAN31955.1 - 0.032 14.2 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 MRP-L46 PF11788.8 EAN31956.1 - 1.5e-07 32.1 2.8 1.2e-06 29.2 2.8 2.2 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 adh_short PF00106.25 EAN31957.1 - 4.3e-30 104.6 0.1 2.4e-25 89.1 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAN31957.1 - 6.1e-19 68.5 0.0 4.4e-16 59.2 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EAN31957.1 - 2.9e-06 26.9 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAN31957.1 - 2e-05 24.6 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EAN31957.1 - 0.00079 18.9 0.0 0.0014 18.1 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EAN31958.1 - 8.5e-34 116.7 0.0 7.7e-28 97.3 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAN31958.1 - 1.8e-16 60.4 0.0 4.1e-13 49.4 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EAN31958.1 - 3.8e-10 39.6 0.0 6.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAN31958.1 - 1.8e-07 31.2 0.0 2.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EAN31958.1 - 7.5e-06 25.6 0.0 2.1e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EAN31958.1 - 0.004 17.1 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAN31958.1 - 0.014 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.15 EAN31958.1 - 0.056 12.6 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PK PF00224.21 EAN31959.1 - 2.3e-139 464.1 2.2 3.4e-139 463.6 2.2 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EAN31959.1 - 6.7e-25 87.6 0.3 1.7e-24 86.3 0.3 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EAN31959.1 - 0.0067 15.6 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF3847 PF12958.7 EAN31959.1 - 0.094 12.8 0.1 0.7 10.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3847) Kelch_4 PF13418.6 EAN31960.1 - 7.9e-32 109.0 3.2 1.1e-10 41.4 0.0 5.4 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EAN31960.1 - 2.6e-26 91.3 10.1 1.9e-09 37.6 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EAN31960.1 - 1.8e-22 78.8 4.6 4.2e-08 33.2 0.1 4.5 3 1 1 4 4 4 4 Kelch motif Kelch_5 PF13854.6 EAN31960.1 - 6.8e-15 54.7 9.2 4.6e-07 29.7 0.4 5.8 5 1 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EAN31960.1 - 5.6e-10 38.6 8.1 0.0036 16.8 0.2 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EAN31960.1 - 4.2e-09 36.0 8.5 0.001 19.0 0.4 5.2 5 0 0 5 5 5 2 Kelch motif Ank_2 PF12796.7 EAN31961.1 - 6.7e-36 122.8 2.9 1.1e-15 58.0 0.2 5.5 2 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 EAN31961.1 - 4.4e-29 99.6 0.6 4.6e-07 30.0 0.0 7.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 EAN31961.1 - 1.6e-26 92.3 1.6 9.9e-10 38.8 0.0 7.2 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAN31961.1 - 1.8e-24 85.5 1.8 4e-09 36.6 0.1 6.6 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAN31961.1 - 1.5e-22 77.2 8.7 8.4e-05 22.7 0.1 9.4 10 0 0 10 10 10 5 Ankyrin repeat NifU PF01106.17 EAN31962.1 - 5.4e-24 84.1 0.1 7.7e-24 83.6 0.1 1.2 1 0 0 1 1 1 1 NifU-like domain Nop52 PF05997.12 EAN31963.1 - 1.3e-40 139.6 1.7 2.4e-40 138.7 1.7 1.5 1 0 0 1 1 1 1 Nucleolar protein,Nop52 GTP_EFTU PF00009.27 EAN31964.1 - 2.6e-28 98.9 0.0 3.7e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAN31964.1 - 0.0017 18.4 0.3 0.006 16.7 0.3 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase TFIIF_alpha PF05793.12 EAN31964.1 - 0.0037 15.9 3.0 0.0059 15.3 3.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Septin PF00735.18 EAN31964.1 - 0.022 14.1 0.4 0.073 12.3 0.4 1.8 1 1 0 1 1 1 0 Septin Dynamin_N PF00350.23 EAN31964.1 - 0.029 14.4 1.7 3.1 7.8 1.7 2.6 1 1 0 1 1 1 0 Dynamin family RsgA_GTPase PF03193.16 EAN31964.1 - 0.055 13.4 1.8 0.58 10.0 0.7 2.6 2 1 0 2 2 2 0 RsgA GTPase PBP1_TM PF14812.6 EAN31964.1 - 0.91 9.9 3.3 1.8 9.0 3.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SNF2_N PF00176.23 EAN31966.1 - 3.9e-50 170.5 1.3 3.9e-50 170.5 1.3 1.8 2 1 0 2 2 2 1 SNF2 family N-terminal domain PHD PF00628.29 EAN31966.1 - 5e-19 67.9 72.4 4.8e-11 42.4 7.9 7.0 6 1 0 6 6 6 4 PHD-finger Helicase_C PF00271.31 EAN31966.1 - 2.9e-16 59.8 0.0 1.4e-15 57.5 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN31966.1 - 2.7e-05 24.2 0.0 2.7e-05 24.2 0.0 3.6 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAN31966.1 - 0.00044 20.1 0.1 0.002 17.9 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase zf-PHD-like PF15446.6 EAN31966.1 - 0.0022 17.6 0.6 0.0022 17.6 0.6 7.3 6 1 1 7 7 7 4 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 EAN31966.1 - 0.0028 17.2 3.0 0.0028 17.2 3.0 8.7 9 0 0 9 9 9 2 PHD-finger Prok-RING_1 PF14446.6 EAN31966.1 - 0.0049 16.8 2.2 0.0049 16.8 2.2 6.9 8 1 0 8 8 8 2 Prokaryotic RING finger family 1 C1_1 PF00130.22 EAN31966.1 - 0.0094 15.8 1.1 0.0094 15.8 1.1 7.2 7 1 1 8 8 8 3 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_14 PF13173.6 EAN31966.1 - 0.02 14.9 0.0 0.094 12.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain PIG-L PF02585.17 EAN31967.1 - 3.4e-14 53.6 0.0 5.2e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Tmemb_14 PF03647.13 EAN31968.1 - 2.2e-05 25.1 6.9 3.2e-05 24.6 6.9 1.3 1 0 0 1 1 1 1 Transmembrane proteins 14C CPP1-like PF11833.8 EAN31968.1 - 0.015 15.0 2.7 0.019 14.6 2.7 1.3 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like EamA PF00892.20 EAN31968.1 - 0.015 15.5 9.8 0.015 15.5 9.8 1.8 1 1 1 2 2 2 0 EamA-like transporter family Intg_mem_TP0381 PF09529.10 EAN31968.1 - 0.022 14.3 12.6 0.025 14.1 12.6 1.0 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) MPC PF03650.13 EAN31968.1 - 0.068 13.3 0.2 0.09 12.9 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial pyruvate carriers UCH_C PF18031.1 EAN31968.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases DUF2070 PF09843.9 EAN31968.1 - 0.98 7.6 11.8 1.2 7.3 11.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF423 PF04241.15 EAN31968.1 - 7.1 6.9 8.4 19 5.6 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF423) FPP PF05911.11 EAN31969.1 - 0.0034 15.7 10.7 0.0039 15.5 10.7 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 EAN31969.1 - 0.0041 16.1 9.0 0.0071 15.3 9.0 1.4 1 1 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.21 EAN31969.1 - 0.01 15.5 8.5 0.011 15.4 7.5 1.5 1 1 0 1 1 1 0 Intermediate filament protein MscS_porin PF12795.7 EAN31969.1 - 0.019 14.5 4.9 0.099 12.2 1.8 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain YscO PF07321.12 EAN31969.1 - 0.02 14.8 0.4 0.062 13.3 0.0 1.7 1 1 1 2 2 2 0 Type III secretion protein YscO Baculo_PEP_C PF04513.12 EAN31969.1 - 0.026 14.6 0.2 0.049 13.7 0.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 EAN31969.1 - 0.028 14.6 6.8 0.057 13.6 6.8 1.6 1 0 0 1 1 1 0 Tropomyosin like PKcGMP_CC PF16808.5 EAN31969.1 - 0.039 13.8 7.2 0.11 12.4 0.7 3.2 4 1 0 4 4 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 EAN31969.1 - 0.04 14.5 7.9 0.86 10.3 0.1 3.5 3 1 1 4 4 3 0 SlyX T3SSipB PF16535.5 EAN31969.1 - 0.044 14.3 2.3 0.078 13.5 2.3 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB BST2 PF16716.5 EAN31969.1 - 0.049 14.2 1.1 0.049 14.2 1.1 2.4 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 YnfE PF17452.2 EAN31969.1 - 0.051 13.9 5.1 0.92 9.8 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized YnfE-like DUF724 PF05266.14 EAN31969.1 - 0.056 13.3 8.4 0.092 12.6 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CC2-LZ PF16516.5 EAN31969.1 - 0.065 13.6 0.6 0.065 13.6 0.6 2.8 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator NTR PF01759.21 EAN31969.1 - 0.12 12.2 1.6 0.44 10.4 0.2 2.1 2 0 0 2 2 2 0 UNC-6/NTR/C345C module Fez1 PF06818.15 EAN31969.1 - 0.14 12.6 8.3 0.1 13.0 6.7 1.6 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.6 EAN31969.1 - 0.14 11.5 1.8 0.16 11.3 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3552 PF12072.8 EAN31969.1 - 0.16 11.3 9.0 9.1 5.6 9.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF641 PF04859.12 EAN31969.1 - 0.2 12.0 6.7 0.34 11.3 0.4 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TolA_bind_tri PF16331.5 EAN31969.1 - 0.22 11.7 6.6 0.75 9.9 3.7 2.8 2 1 0 2 2 2 0 TolA binding protein trimerisation Macoilin PF09726.9 EAN31969.1 - 0.52 8.8 12.7 0.62 8.5 12.7 1.1 1 0 0 1 1 1 0 Macoilin family ATG16 PF08614.11 EAN31969.1 - 0.56 10.4 9.6 1.6 8.9 9.6 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 EAN31969.1 - 1.1 9.7 12.2 0.66 10.4 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HIP1_clath_bdg PF16515.5 EAN31969.1 - 1.3 9.7 7.7 0.66 10.6 1.4 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 EAN31969.1 - 1.7 8.7 6.9 0.42 10.7 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EAN31969.1 - 3 7.0 8.4 1.6 7.9 6.1 1.6 1 1 1 2 2 2 0 TMPIT-like protein Atg14 PF10186.9 EAN31969.1 - 3 6.8 14.5 0.31 10.1 8.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 EAN31969.1 - 3.6 7.8 12.9 6.8 6.9 6.6 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PRKG1_interact PF15898.5 EAN31969.1 - 4 8.4 11.0 0.41 11.6 4.9 2.3 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain KASH_CCD PF14662.6 EAN31969.1 - 4.7 7.0 14.6 1.8 8.4 11.1 2.1 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Proteasome PF00227.26 EAN31970.1 - 6.1e-42 143.3 0.0 6.9e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Terminase_4 PF05119.12 EAN31971.1 - 0.19 12.2 0.0 0.78 10.2 0.0 2.1 2 0 0 2 2 2 0 Phage terminase, small subunit Iso_dh PF00180.20 EAN31972.1 - 4.6e-64 216.8 0.0 5.6e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Mre11_DNA_bind PF04152.14 EAN31973.1 - 6.3e-23 81.9 0.2 2.4e-22 80.1 0.2 2.0 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EAN31973.1 - 4.7e-10 40.3 4.8 4.7e-10 40.3 4.8 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAN31973.1 - 4.6e-06 26.9 0.0 0.0045 17.2 0.0 2.8 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain GerPC PF10737.9 EAN31973.1 - 0.054 13.5 1.9 6.8 6.7 0.3 2.4 2 0 0 2 2 2 0 Spore germination protein GerPC tRNA-synt_2d PF01409.20 EAN31974.1 - 6e-77 258.4 0.0 8.4e-77 258.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EAN31974.1 - 1.1e-07 32.0 0.1 3.5e-07 30.4 0.1 1.9 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EAN31974.1 - 0.0063 16.0 0.0 0.045 13.2 0.0 2.0 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EAN31974.1 - 0.011 14.8 0.0 0.072 12.2 0.0 2.2 3 0 0 3 3 3 0 tRNA synthetases class II (D, K and N) RQC PF09382.10 EAN31974.1 - 0.12 12.1 0.3 0.61 9.9 0.1 2.1 2 0 0 2 2 2 0 RQC domain tRNA-synt_2b PF00587.25 EAN31974.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) TBCA PF02970.16 EAN31975.1 - 2.7e-18 66.1 3.5 5.5e-18 65.1 3.5 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor A Acetyltransf_10 PF13673.7 EAN31976.1 - 9.6e-14 51.4 0.0 1.1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAN31976.1 - 2.9e-13 50.1 0.0 3.5e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAN31976.1 - 1.7e-08 34.7 0.0 2.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAN31976.1 - 4.7e-06 26.5 0.0 7.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EAN31976.1 - 0.011 15.9 0.6 0.014 15.5 0.6 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NUDIX_2 PF13869.6 EAN31978.1 - 2.6e-62 209.7 0.0 3.1e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase LCCL PF03815.19 EAN31979.1 - 9.2e-05 22.5 1.3 0.0002 21.4 1.3 1.6 1 0 0 1 1 1 1 LCCL domain PA14 PF07691.12 EAN31980.1 - 2.3e-22 79.4 0.1 5e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 PA14 domain fn2 PF00040.19 EAN31980.1 - 0.00077 19.7 0.8 0.0022 18.3 0.8 1.9 1 0 0 1 1 1 1 Fibronectin type II domain PhoU PF01895.19 EAN31980.1 - 0.082 13.4 2.6 0.88 10.1 0.2 2.5 2 0 0 2 2 2 0 PhoU domain GLEYA PF10528.9 EAN31980.1 - 0.11 12.9 4.3 0.16 12.4 0.0 3.2 3 1 0 3 3 3 0 GLEYA domain Prefoldin_2 PF01920.20 EAN31980.1 - 0.22 11.5 5.7 0.62 10.0 5.7 1.8 1 0 0 1 1 1 0 Prefoldin subunit Mito_carr PF00153.27 EAN31982.1 - 1.1e-05 25.3 0.1 0.014 15.3 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein LAGLIDADG_2 PF03161.13 EAN31982.1 - 0.093 12.8 1.6 0.1 12.6 0.6 1.6 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family RRM_8 PF11835.8 EAN31982.1 - 0.19 11.9 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain PAP2_C PF14360.6 EAN31983.1 - 2.3e-17 63.3 12.9 2.3e-17 63.3 12.9 3.0 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 EAN31983.1 - 3.1e-09 36.7 6.8 3.1e-09 36.7 6.8 2.2 2 1 0 2 2 2 1 PAP2 superfamily ATP-synt_I PF03899.15 EAN31983.1 - 0.0081 16.5 18.7 0.032 14.6 0.5 3.4 3 0 0 3 3 3 2 ATP synthase I chain PAP2_3 PF14378.6 EAN31983.1 - 0.43 10.2 20.2 0.067 12.9 14.8 2.2 2 1 0 2 2 2 0 PAP2 superfamily PAP2_C PF14360.6 EAN31984.1 - 5.5e-13 49.3 7.8 5.5e-13 49.3 7.8 2.2 2 0 0 2 2 1 1 PAP2 superfamily C-terminal Rad17 PF03215.15 EAN31984.1 - 1.9e-09 37.7 0.1 1.9e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 EAN31984.1 - 3.6e-08 33.9 0.0 1.3e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAN31984.1 - 8e-05 23.1 0.0 0.00039 20.8 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EAN31984.1 - 0.00077 20.0 2.9 0.0032 18.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAN31984.1 - 0.0012 18.8 0.0 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase PAP2 PF01569.21 EAN31984.1 - 0.0015 18.3 5.2 0.0015 18.3 5.2 1.7 2 0 0 2 2 2 1 PAP2 superfamily RuvB_N PF05496.12 EAN31984.1 - 0.0018 18.0 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain PAP2_3 PF14378.6 EAN31984.1 - 0.002 17.8 3.7 0.0044 16.7 3.7 1.5 1 0 0 1 1 1 1 PAP2 superfamily AAA_14 PF13173.6 EAN31984.1 - 0.0033 17.4 0.1 0.042 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EAN31984.1 - 0.0072 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 EAN31984.1 - 0.0093 16.0 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EAN31984.1 - 0.024 14.5 2.4 1.4 8.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EAN31984.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAN31984.1 - 0.096 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EAN31984.1 - 0.1 11.8 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 EAN31984.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 EAN31984.1 - 0.11 12.6 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 EAN31984.1 - 0.18 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain OPA3 PF07047.12 EAN31986.1 - 3e-11 43.2 0.2 4.3e-11 42.7 0.2 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF3045 PF11243.8 EAN31987.1 - 0.011 15.9 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) Longin_2 PF18639.1 EAN31987.1 - 0.094 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Yeast longin domain Fe-S_biosyn PF01521.20 EAN31988.1 - 3.3e-11 43.4 0.1 4.6e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis D123 PF07065.14 EAN31989.1 - 3e-30 105.4 10.5 1.7e-28 99.7 10.5 2.1 1 1 0 1 1 1 1 D123 DUF4268 PF14088.6 EAN31990.1 - 0.037 13.9 0.0 0.038 13.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) Sec1 PF00995.23 EAN31991.1 - 3.4e-72 244.5 10.0 4.2e-72 244.2 10.0 1.1 1 0 0 1 1 1 1 Sec1 family PIG-P PF08510.12 EAN31992.1 - 7.8e-11 41.9 1.4 8.5e-11 41.8 1.4 1.0 1 0 0 1 1 1 1 PIG-P OTU PF02338.19 EAN31994.1 - 0.14 12.6 0.4 2 9.0 0.4 2.3 1 1 0 1 1 1 0 OTU-like cysteine protease GATA PF00320.27 EAN31995.1 - 4.3e-07 29.4 3.3 9e-07 28.4 3.3 1.6 1 0 0 1 1 1 1 GATA zinc finger ESAG1 PF03238.13 EAN31996.1 - 0.01 15.3 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 0 ESAG protein Pkinase PF00069.25 EAN31997.1 - 9.6e-37 126.8 0.0 5.5e-22 78.4 0.1 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAN31997.1 - 7.5e-10 38.5 0.0 0.0012 18.2 0.0 3.0 2 2 0 2 2 2 2 Protein tyrosine kinase HSP90 PF00183.18 EAN31998.1 - 1.2e-141 473.1 12.9 1.2e-141 473.1 12.9 2.6 2 1 0 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.6 EAN31998.1 - 1e-12 48.1 1.5 1.4e-11 44.3 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EAN31998.1 - 4.4e-09 36.8 0.0 2.5e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OS-D PF03392.13 EAN31999.1 - 0.068 13.3 0.1 0.37 10.9 0.0 2.3 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D RasGAP_C PF03836.15 EAN31999.1 - 0.35 11.0 3.6 0.29 11.3 1.1 2.1 2 0 0 2 2 2 0 RasGAP C-terminus RNA_pol_Rpb1_5 PF04998.17 EAN32000.1 - 1.4e-85 287.0 0.2 2.4e-85 286.2 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EAN32000.1 - 5.7e-79 265.7 4.6 5.7e-79 265.7 4.6 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EAN32000.1 - 4.5e-70 235.2 0.0 9.1e-70 234.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EAN32000.1 - 2.4e-32 112.1 0.0 2e-31 109.1 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EAN32000.1 - 1.3e-29 102.3 0.0 6.7e-29 100.0 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zinc_ribbon_15 PF17032.5 EAN32000.1 - 1.4 9.7 5.8 5.2 7.9 5.8 2.0 1 0 0 1 1 1 0 zinc-ribbon family Gpi16 PF04113.14 EAN32001.1 - 3.2e-17 62.2 0.3 5.2e-07 28.5 0.0 3.0 3 0 0 3 3 3 3 Gpi16 subunit, GPI transamidase component Ribosomal_S15 PF00312.22 EAN32002.1 - 1.5e-15 57.2 0.1 1.5e-15 57.2 0.1 2.3 2 1 0 2 2 2 1 Ribosomal protein S15 PNP_phzG_C PF10590.9 EAN32002.1 - 0.19 11.8 1.8 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region DUF2642 PF10842.8 EAN32003.1 - 0.054 13.4 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) GlutR_dimer PF00745.20 EAN32003.1 - 0.13 12.7 0.1 1.5 9.3 0.1 2.4 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Uteroglobin PF01099.17 EAN32003.1 - 5.2 7.5 9.7 2.9 8.3 0.3 4.0 2 2 3 5 5 5 0 Uteroglobin family TNFR_16_TM PF18422.1 EAN32004.1 - 3.8 7.6 6.3 1.9 8.5 0.4 2.4 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Helicase_C PF00271.31 EAN32005.1 - 1.3e-14 54.4 0.6 7.1e-14 52.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAN32005.1 - 2.6e-13 50.1 0.0 2e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 EAN32005.1 - 0.004 17.2 0.1 1.1 9.3 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit THP2 PF09432.10 EAN32005.1 - 0.95 9.5 4.8 1.4 9.0 0.3 3.3 3 1 1 4 4 4 0 Tho complex subunit THP2 MFS_1 PF07690.16 EAN32007.1 - 5.6e-05 22.2 2.7 0.0019 17.2 0.3 2.8 3 0 0 3 3 3 1 Major Facilitator Superfamily CdvA PF18822.1 EAN32007.1 - 0.0029 17.4 4.9 0.0029 17.4 4.9 2.3 2 0 0 2 2 2 1 CdvA-like coiled-coil domain DivIC PF04977.15 EAN32007.1 - 0.47 10.3 8.4 1.5 8.6 1.3 3.6 3 1 1 4 4 4 0 Septum formation initiator Baculo_PEP_C PF04513.12 EAN32007.1 - 0.58 10.2 6.3 0.28 11.2 3.6 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.9 EAN32007.1 - 0.96 10.2 5.4 2.2 9.0 1.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Phage_holin_1 PF04531.13 EAN32007.1 - 1 9.9 7.4 1.2 9.7 0.4 3.3 3 0 0 3 3 3 0 Bacteriophage holin DUF1664 PF07889.12 EAN32007.1 - 4.3 7.4 12.2 0.61 10.1 2.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Connexin PF00029.19 EAN32009.1 - 0.00098 18.9 0.2 0.00098 18.9 0.2 2.2 2 0 0 2 2 2 1 Connexin ABC_ATPase PF09818.9 EAN32011.1 - 3.4e-179 596.3 0.0 4.5e-179 595.9 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 EAN32011.1 - 0.00018 22.1 0.3 0.00049 20.7 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAN32011.1 - 0.041 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Lyase_aromatic PF00221.19 EAN32011.1 - 0.23 10.1 0.0 0.32 9.6 0.0 1.1 1 0 0 1 1 1 0 Aromatic amino acid lyase Pkinase PF00069.25 EAN32012.1 - 5.2e-67 226.0 0.8 6.8e-67 225.6 0.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32012.1 - 2.4e-24 86.0 0.0 3.5e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAN32012.1 - 1.7e-07 31.5 0.0 3.3e-06 27.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAN32012.1 - 0.004 16.0 0.1 0.012 14.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EAN32012.1 - 0.029 13.7 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aconitase_B_N PF11791.8 EAN32012.1 - 0.081 13.0 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Aconitate B N-terminal domain CoA_binding PF02629.19 EAN32013.1 - 5.6e-25 87.9 0.3 4.9e-24 84.8 0.0 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EAN32013.1 - 1.2e-20 73.9 0.4 1.8e-20 73.3 0.4 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EAN32013.1 - 9.6e-09 35.2 0.0 2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain SseB PF07179.12 EAN32013.1 - 0.096 13.0 0.0 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 SseB protein N-terminal domain RtcB PF01139.17 EAN32014.1 - 6.4e-144 480.2 0.0 7.3e-144 480.0 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Pinin_SDK_N PF04697.13 EAN32015.1 - 0.0068 17.1 0.7 0.015 15.9 0.6 1.6 1 1 0 1 1 1 1 pinin/SDK conserved region Marek_SORF3 PF07153.11 EAN32015.1 - 0.016 14.5 0.2 0.031 13.6 0.2 1.4 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein TIP49 PF06068.13 EAN32016.1 - 2.4e-143 477.6 0.5 1.3e-89 300.8 0.1 2.0 1 1 0 2 2 2 2 TIP49 P-loop domain AAA PF00004.29 EAN32016.1 - 4.8e-08 33.5 1.1 1.3e-05 25.7 0.1 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAN32016.1 - 2.3e-07 30.7 0.4 2.6e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAN32016.1 - 3.5e-05 24.1 0.0 0.32 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EAN32016.1 - 0.00015 21.2 0.2 0.0045 16.4 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EAN32016.1 - 0.00016 22.1 0.0 0.00024 21.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EAN32016.1 - 0.00032 20.7 0.1 0.0076 16.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 EAN32016.1 - 0.00064 19.1 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 EAN32016.1 - 0.00066 19.3 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EAN32016.1 - 0.0023 17.9 0.1 0.0046 16.9 0.1 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EAN32016.1 - 0.0029 17.5 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 EAN32016.1 - 0.0037 17.8 0.1 0.0067 16.9 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 EAN32016.1 - 0.0073 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EAN32016.1 - 0.0096 16.4 0.0 0.03 14.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 EAN32016.1 - 0.013 15.6 0.0 0.74 9.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 EAN32016.1 - 0.014 15.8 0.0 0.036 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EAN32016.1 - 0.015 14.8 0.1 0.036 13.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EAN32016.1 - 0.018 14.8 0.1 0.51 10.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EAN32016.1 - 0.024 13.9 0.1 0.039 13.2 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 EAN32016.1 - 0.03 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EAN32016.1 - 0.031 14.4 0.2 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 EAN32016.1 - 0.048 13.6 0.4 0.14 12.1 0.0 1.9 2 1 0 2 2 2 0 Rad17 P-loop domain ResIII PF04851.15 EAN32016.1 - 0.052 13.6 0.2 0.24 11.4 0.2 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit APS_kinase PF01583.20 EAN32016.1 - 0.069 13.0 0.1 0.21 11.5 0.1 1.9 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_29 PF13555.6 EAN32016.1 - 0.076 12.8 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EAN32016.1 - 0.1 12.9 1.8 0.92 9.8 1.8 2.3 1 1 0 1 1 1 0 AAA domain Peptidase_C2 PF00648.21 EAN32017.1 - 5.5e-29 101.1 0.0 2.2e-28 99.1 0.0 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EAN32017.1 - 0.0059 16.9 2.6 0.56 10.5 1.2 3.4 2 1 0 2 2 2 1 Calpain large subunit, domain III Urocanase_N PF17391.2 EAN32017.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Urocanase N-terminal domain Enterotoxin_ST PF02048.16 EAN32017.1 - 9.8 6.7 8.1 3.2 8.3 3.8 2.3 2 0 0 2 2 2 0 Heat-stable enterotoxin ST FAT PF02259.23 EAN32018.1 - 6.4e-11 42.1 3.8 6.4e-11 42.1 3.8 2.9 3 0 0 3 3 3 1 FAT domain WD40 PF00400.32 EAN32019.1 - 1.2e-40 136.7 25.8 1.4e-06 28.9 3.6 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN32019.1 - 6.1e-06 26.4 2.6 1 9.7 0.1 5.2 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAN32019.1 - 2.2e-05 23.3 4.8 0.43 9.2 0.0 3.5 1 1 2 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EAN32019.1 - 8.9e-05 22.0 0.4 0.17 11.2 0.1 3.0 1 1 2 3 3 3 2 WD40-like domain BBS2_Mid PF14783.6 EAN32019.1 - 0.01 15.8 1.3 11 6.1 0.0 3.8 4 2 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Hira PF07569.11 EAN32019.1 - 0.33 10.6 1.8 4.9 6.8 0.1 3.1 3 1 1 4 4 4 0 TUP1-like enhancer of split KH_1 PF00013.29 EAN32020.1 - 5.9e-10 38.8 0.0 3.9e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 KH domain Ses_B PF17046.5 EAN32020.1 - 0.02 14.8 1.5 2 8.5 0.4 3.0 3 0 0 3 3 3 0 SesB domain on fungal death-pathway protein Cas_Cas1 PF01867.16 EAN32020.1 - 0.023 13.8 0.1 0.054 12.6 0.0 1.6 2 0 0 2 2 2 0 CRISPR associated protein Cas1 SRP1_TIP1 PF00660.17 EAN32020.1 - 0.076 13.1 2.0 0.19 11.8 2.0 1.6 1 0 0 1 1 1 0 Seripauperin and TIP1 family HCNGP PF07818.13 EAN32020.1 - 0.099 13.3 0.9 1.3 9.8 0.0 2.8 2 1 1 3 3 3 0 HCNGP-like protein DUF1682 PF07946.14 EAN32021.1 - 1.1e-41 143.1 1.2 1.5e-41 142.7 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) zf-rbx1 PF12678.7 EAN32022.1 - 9.5e-25 86.7 13.2 1.2e-24 86.3 13.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAN32022.1 - 4.7e-13 49.0 13.0 2e-12 47.0 13.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EAN32022.1 - 5.1e-06 26.7 15.5 0.00096 19.4 15.5 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAN32022.1 - 5.3e-05 23.0 2.0 5.3e-05 23.0 2.0 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAN32022.1 - 0.00044 20.0 10.3 0.0057 16.5 10.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAN32022.1 - 0.002 17.8 1.3 0.002 17.8 1.3 2.5 2 1 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EAN32022.1 - 0.022 14.8 9.1 0.12 12.4 9.1 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EAN32022.1 - 0.035 14.1 11.3 0.49 10.4 11.4 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EAN32022.1 - 0.089 13.0 0.3 0.089 13.0 0.3 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EAN32022.1 - 0.25 11.6 8.9 1.7 8.9 9.2 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain CTV_P23 PF04808.12 EAN32022.1 - 0.34 10.4 1.0 1.2 8.7 1.2 1.7 1 1 0 1 1 1 0 Citrus tristeza virus (CTV) P23 protein zf-C3HC4_3 PF13920.6 EAN32022.1 - 0.38 10.6 10.7 8.7 6.3 0.3 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EAN32022.1 - 1.1 8.9 13.7 0.075 12.7 3.2 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EAN32023.1 - 9.5e-10 38.9 4.7 0.02 15.8 0.3 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN32023.1 - 1.4e-09 38.1 0.0 0.014 15.7 0.0 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain IBN_N PF03810.19 EAN32024.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Importin-beta N-terminal domain RAP PF08373.10 EAN32025.1 - 2e-06 27.8 0.1 7.8e-06 25.9 0.1 2.1 1 0 0 1 1 1 1 RAP domain DUF4976 PF16347.5 EAN32025.1 - 0.016 15.5 1.7 0.036 14.3 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4976) DUF3887 PF13026.6 EAN32025.1 - 0.25 12.2 4.6 0.59 11.0 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3887) EF-hand_1 PF00036.32 EAN32026.1 - 2.7e-09 35.9 0.1 4.6e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EAN32026.1 - 1.7e-08 33.7 0.5 2.7e-08 33.1 0.4 1.5 1 1 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EAN32026.1 - 3.3e-06 27.5 0.1 4.4e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EAN32026.1 - 9.3e-05 21.7 0.1 0.00021 20.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EAN32026.1 - 0.0007 19.4 0.2 0.003 17.4 0.1 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_14 PF17959.1 EAN32026.1 - 0.034 14.5 0.1 0.042 14.2 0.1 1.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_4 PF12763.7 EAN32026.1 - 0.18 11.7 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand CENP-T_C PF15511.6 EAN32028.1 - 2.2e-09 37.4 0.1 2.6e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EAN32028.1 - 6.6e-05 23.2 0.1 9.7e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EAN32028.1 - 0.00049 20.2 0.0 0.00065 19.8 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EAN32028.1 - 0.0017 18.6 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAN32028.1 - 0.012 16.0 0.1 0.012 15.9 0.1 1.3 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EAN32028.1 - 0.034 14.1 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 EAN32028.1 - 0.039 14.0 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TAFII28 PF04719.14 EAN32028.1 - 0.11 12.5 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region TIM PF00121.18 EAN32029.1 - 4.5e-35 121.2 0.1 9.8e-23 80.8 0.1 2.1 1 1 1 2 2 2 2 Triosephosphate isomerase CENP-T_C PF15511.6 EAN32030.1 - 2.2e-09 37.4 0.1 2.6e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EAN32030.1 - 6.6e-05 23.2 0.1 9.7e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EAN32030.1 - 0.00049 20.2 0.0 0.00065 19.8 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EAN32030.1 - 0.0017 18.6 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAN32030.1 - 0.012 16.0 0.1 0.012 15.9 0.1 1.3 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EAN32030.1 - 0.034 14.1 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 EAN32030.1 - 0.039 14.0 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TAFII28 PF04719.14 EAN32030.1 - 0.11 12.5 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Pkinase PF00069.25 EAN32031.1 - 5.3e-44 150.6 0.0 9.8e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32031.1 - 4.7e-16 58.8 0.0 8.3e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAN32031.1 - 5e-08 32.1 0.0 9.5e-08 31.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAN32031.1 - 4.8e-06 26.1 0.0 8.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAN32031.1 - 0.00097 19.1 0.0 0.01 15.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EAN32031.1 - 0.044 12.7 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 EAN32031.1 - 0.14 11.4 0.3 1.7 7.9 0.3 2.1 1 1 0 1 1 1 0 Kinase-like EF-hand_6 PF13405.6 EAN32032.1 - 5.9e-12 44.5 3.5 4.9e-07 29.2 0.3 4.1 3 1 1 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EAN32032.1 - 8.2e-12 45.4 10.5 7.2e-07 29.6 0.7 2.6 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EAN32032.1 - 2.8e-10 39.0 6.5 6.5e-07 28.5 0.7 4.1 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 EAN32032.1 - 2.9e-08 33.4 2.6 0.011 15.5 0.5 4.2 1 1 3 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EAN32032.1 - 0.00068 19.0 0.4 0.0031 16.9 0.4 2.3 1 0 0 1 1 1 1 EF hand Caleosin PF05042.13 EAN32032.1 - 0.051 13.5 0.3 8.1 6.3 0.0 2.8 1 1 2 3 3 3 0 Caleosin related protein Herpes_BLRF2 PF05812.12 EAN32032.1 - 0.056 13.6 0.2 0.13 12.4 0.1 1.7 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein TerB PF05099.13 EAN32032.1 - 0.095 12.7 0.1 0.9 9.5 0.2 2.0 1 1 1 2 2 2 0 Tellurite resistance protein TerB Cytochrom_C552 PF02335.15 EAN32032.1 - 0.13 11.2 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c552 Ribosomal_S4e PF00900.20 EAN32033.1 - 5.8e-29 99.8 0.7 9e-29 99.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 EAN32033.1 - 6e-21 73.8 0.0 9.9e-21 73.1 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EAN32033.1 - 3e-18 65.6 6.9 3e-18 65.6 6.9 2.0 2 0 0 2 2 2 1 RS4NT (NUC023) domain KOW PF00467.29 EAN32033.1 - 4.5e-07 29.6 4.4 5.2e-07 29.4 1.7 2.6 2 0 0 2 2 2 1 KOW motif S4 PF01479.25 EAN32033.1 - 3.7e-06 26.6 0.1 6.9e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 S4 domain MRP-S32 PF10210.9 EAN32033.1 - 0.043 14.4 0.1 0.54 10.8 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 Sipho_tail PF05709.11 EAN32033.1 - 0.077 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Phage tail protein EF-hand_7 PF13499.6 EAN32034.1 - 1.4e-27 95.9 12.3 3.1e-12 46.8 0.2 3.6 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EAN32034.1 - 7.3e-27 91.6 17.2 2.4e-06 26.8 0.3 5.6 5 0 0 5 5 5 5 EF hand EF-hand_1 PF00036.32 EAN32034.1 - 3.7e-25 85.6 18.3 8.5e-05 21.8 0.6 6.1 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 EAN32034.1 - 1e-23 81.2 16.0 3.7e-06 26.4 0.2 6.3 6 1 0 6 6 6 5 EF-hand domain SPARC_Ca_bdg PF10591.9 EAN32034.1 - 1.8e-12 47.5 5.5 0.00015 22.0 0.4 3.3 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EAN32034.1 - 2.1e-11 43.5 11.1 0.0031 17.3 0.0 5.3 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_10 PF14788.6 EAN32034.1 - 0.0012 18.7 3.3 5.1 7.0 0.2 3.8 3 0 0 3 3 3 2 EF hand EF-hand_11 PF08976.11 EAN32034.1 - 0.043 14.7 0.0 0.11 13.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain PMBR PF09373.10 EAN32034.1 - 0.084 13.1 0.7 99 3.4 0.1 3.8 3 0 0 3 3 3 0 Pseudomurein-binding repeat DHR10 PF18595.1 EAN32035.1 - 3.2 7.8 10.2 0.16 12.0 3.8 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain HSP70 PF00012.20 EAN32036.1 - 4.2e-243 807.9 10.4 4.9e-243 807.7 10.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAN32036.1 - 1.3e-20 73.5 2.5 3.3e-20 72.2 0.4 2.2 1 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EAN32036.1 - 0.00055 20.3 6.9 3.5 8.1 0.0 3.9 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 EAN32036.1 - 0.021 14.6 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain GLE1 PF07817.13 EAN32036.1 - 0.044 13.0 1.1 0.23 10.7 0.0 2.4 3 0 0 3 3 3 0 GLE1-like protein DDR PF08841.10 EAN32036.1 - 0.054 12.5 0.9 0.43 9.5 0.9 2.2 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 EAN32036.1 - 0.13 11.5 5.5 0.72 9.1 0.2 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF2706 PF10913.8 EAN32036.1 - 0.17 11.8 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) SpoIIAA-like PF11964.8 EAN32036.1 - 0.71 11.0 3.0 0.97 10.5 0.2 2.6 2 1 0 2 2 2 0 SpoIIAA-like DUF5339 PF17274.2 EAN32036.1 - 2 9.3 6.4 17 6.3 0.2 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5339) Fib_alpha PF08702.10 EAN32036.1 - 4.1 7.6 11.9 8.2 6.6 1.8 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1712 PF08217.11 EAN32038.1 - 3.3e-08 32.5 0.0 3.3e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) TraS PF10624.9 EAN32039.1 - 0.02 14.8 0.6 0.042 13.8 0.4 1.6 1 1 1 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS TPR_1 PF00515.28 EAN32040.1 - 0.0014 18.4 7.7 0.0041 16.9 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat SART-1 PF03343.13 EAN32040.1 - 0.0019 16.8 2.2 0.0029 16.2 2.2 1.2 1 0 0 1 1 1 1 SART-1 family TPR_2 PF07719.17 EAN32040.1 - 0.059 13.5 6.9 0.095 12.9 0.0 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.31 EAN32041.1 - 1.7e-22 79.3 1.3 1.7e-22 79.3 1.3 1.8 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 EAN32041.1 - 0.0037 17.2 0.2 0.01 15.8 0.2 1.7 1 0 0 1 1 1 1 Thioredoxin Acetyltransf_1 PF00583.25 EAN32042.1 - 5e-10 39.6 0.0 9.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAN32042.1 - 0.0021 18.5 0.1 0.008 16.6 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAN32042.1 - 0.0048 16.8 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EAN32042.1 - 0.0052 16.9 0.0 0.0094 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RNase_T PF00929.24 EAN32042.1 - 0.12 12.9 0.2 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 Exonuclease His_Phos_1 PF00300.22 EAN32043.1 - 6.7e-38 130.3 0.0 8.1e-31 107.2 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) TAF6_C PF07571.13 EAN32043.1 - 0.18 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain Hydrolase_4 PF12146.8 EAN32044.1 - 0.00013 21.3 0.5 0.0026 17.1 0.1 2.5 2 1 0 3 3 3 1 Serine aminopeptidase, S33 DUF818 PF05677.12 EAN32044.1 - 0.0012 17.9 0.7 0.0019 17.2 0.7 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_1 PF00561.20 EAN32044.1 - 0.0013 18.5 0.4 0.0024 17.6 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PPP1R32 PF15691.5 EAN32044.1 - 0.029 13.5 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 32 Abhydrolase_6 PF12697.7 EAN32044.1 - 0.033 14.8 0.0 0.059 14.0 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family LIP PF03583.14 EAN32044.1 - 0.094 12.0 0.1 0.23 10.7 0.0 1.6 1 1 0 1 1 1 0 Secretory lipase RecX PF02631.16 EAN32047.1 - 0.01 16.3 0.1 0.021 15.3 0.1 1.6 1 1 0 1 1 1 0 RecX family Fis1_TPR_N PF14852.6 EAN32047.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat Sel1 PF08238.12 EAN32048.1 - 3.3e-17 62.5 1.1 3e-05 24.5 0.0 5.7 5 0 0 5 5 5 4 Sel1 repeat SART-1 PF03343.13 EAN32049.1 - 4.4e-53 180.8 40.6 4.9e-33 114.6 32.4 3.0 1 1 1 2 2 2 2 SART-1 family DUF4256 PF14066.6 EAN32049.1 - 0.0043 16.8 0.5 0.0084 15.8 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4256) Op_neuropeptide PF08035.11 EAN32049.1 - 0.064 13.1 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Opioids neuropeptide BSD PF03909.17 EAN32050.1 - 0.0016 18.4 0.5 0.0016 18.4 0.5 3.0 3 0 0 3 3 3 1 BSD domain DUF2756 PF10956.8 EAN32051.1 - 0.0046 17.4 0.1 0.0056 17.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2756) TUDOR PF00567.24 EAN32052.1 - 0.00048 20.2 0.6 0.0014 18.7 0.0 2.1 2 2 1 3 3 3 1 Tudor domain SMN PF06003.12 EAN32052.1 - 0.055 12.7 0.2 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Enolase_C PF00113.22 EAN32053.1 - 2.5e-151 503.0 0.0 3.2e-151 502.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EAN32053.1 - 1.6e-53 180.4 0.1 3.3e-53 179.3 0.1 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EAN32053.1 - 7.4e-09 35.5 0.0 1.7e-08 34.3 0.0 1.6 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EAN32053.1 - 8.2e-07 28.4 0.1 1.3e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Dak1_2 PF13684.6 EAN32054.1 - 0.01 14.9 1.0 0.016 14.3 1.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Membralin PF09746.9 EAN32054.1 - 1.9 7.4 9.6 2.7 6.9 9.6 1.3 1 0 0 1 1 1 0 Tumour-associated protein B-block_TFIIIC PF04182.12 EAN32055.1 - 3e-05 24.1 0.0 8.5e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC DKNYY PF13644.6 EAN32055.1 - 0.047 14.5 0.5 0.057 14.2 0.5 1.2 1 0 0 1 1 1 0 DKNYY family B-block_TFIIIC PF04182.12 EAN32056.1 - 0.0025 17.9 0.2 0.12 12.5 0.1 3.2 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC GED PF02212.18 EAN32056.1 - 0.015 15.4 1.4 0.16 12.1 0.1 3.0 2 0 0 2 2 2 0 Dynamin GTPase effector domain Maf PF02545.14 EAN32058.1 - 2e-38 131.9 0.0 2.4e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein LytR_C PF13399.6 EAN32058.1 - 0.031 15.3 0.2 0.27 12.2 0.0 2.1 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator eIF3_p135 PF12807.7 EAN32059.1 - 1.9e-08 34.6 0.0 5.4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.6 EAN32059.1 - 7.7e-05 22.6 0.0 0.00023 21.0 0.0 1.8 1 0 0 1 1 1 1 Clustered mitochondria Thg1 PF04446.12 EAN32059.1 - 0.086 12.9 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 tRNAHis guanylyltransferase Claudin_2 PF13903.6 EAN32060.1 - 0.0092 15.7 17.7 0.25 11.0 3.6 4.7 5 0 0 5 5 5 3 PMP-22/EMP/MP20/Claudin tight junction Alpha_E2_glycop PF00943.19 EAN32060.1 - 0.14 10.8 0.4 1.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Alphavirus E2 glycoprotein DUF2207 PF09972.9 EAN32061.1 - 0.058 12.1 5.7 0.11 11.2 5.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DEAD PF00270.29 EAN32062.1 - 6.1e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sdh5 PF03937.16 EAN32062.1 - 0.032 14.2 0.0 0.084 12.8 0.0 1.7 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Helicase_C PF00271.31 EAN32063.1 - 0.0029 17.9 0.7 0.0081 16.5 0.7 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Ribosomal_60s PF00428.19 EAN32064.1 - 1.7e-23 83.0 9.0 2.3e-23 82.6 9.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein FANCI_S1-cap PF14674.6 EAN32064.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.7 1 1 0 1 1 1 0 FANCI solenoid 1 cap Cytomega_UL84 PF06284.11 EAN32064.1 - 4.4 5.7 9.3 4.2 5.7 8.4 1.4 1 1 1 2 2 2 0 Cytomegalovirus UL84 protein Cytochrom_C PF00034.21 EAN32065.1 - 1.2e-08 35.9 0.0 2.6e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EAN32065.1 - 0.00097 19.4 0.2 0.0013 19.0 0.2 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EAN32065.1 - 0.0014 18.3 0.0 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.15 EAN32065.1 - 0.045 13.5 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C1 family eIF2A PF08662.11 EAN32065.1 - 0.11 12.3 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A ATP-synt_ab PF00006.25 EAN32067.1 - 3.4e-98 327.5 0.0 4.8e-98 327.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EAN32067.1 - 2e-38 130.9 0.0 3.3e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EAN32067.1 - 1.6e-15 57.4 0.4 4.3e-15 56.0 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain GYF PF02213.16 EAN32068.1 - 0.00059 19.4 2.3 0.0015 18.1 2.3 1.8 1 0 0 1 1 1 1 GYF domain AAA_12 PF13087.6 EAN32069.1 - 5e-59 199.3 0.3 5e-59 199.3 0.3 2.2 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EAN32069.1 - 3.1e-58 197.6 3.5 2.7e-28 99.5 0.3 2.8 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EAN32069.1 - 4.9e-08 32.9 0.1 5.7e-05 22.9 0.0 2.9 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 EAN32069.1 - 7.1e-08 32.9 0.1 0.0045 17.3 0.4 3.1 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EAN32069.1 - 1.1e-05 25.3 0.1 0.0075 16.0 0.0 3.3 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 EAN32069.1 - 0.00091 19.8 2.9 0.0028 18.2 2.9 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EAN32069.1 - 0.031 14.0 0.0 0.16 11.7 0.0 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase Rad17 PF03215.15 EAN32069.1 - 0.033 14.1 1.4 0.17 11.8 1.4 2.2 1 1 1 2 2 2 0 Rad17 P-loop domain T2SSE PF00437.20 EAN32069.1 - 0.042 12.9 0.1 0.081 12.0 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 EAN32069.1 - 0.042 14.3 0.0 0.095 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EAN32069.1 - 0.085 12.6 0.3 0.24 11.2 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD_C_2 PF13538.6 EAN32069.1 - 0.19 11.6 0.1 30 4.5 0.0 2.5 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 EAN32069.1 - 0.22 11.5 5.8 0.58 10.1 2.9 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Acetyltransf_1 PF00583.25 EAN32070.1 - 0.021 15.1 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAN32070.1 - 0.046 13.7 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Med28 PF11594.8 EAN32071.1 - 0.051 13.7 3.8 0.081 13.0 0.2 2.3 2 1 1 3 3 3 0 Mediator complex subunit 28 APG17 PF04108.12 EAN32071.1 - 1 8.4 6.5 0.77 8.8 2.1 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 DASH_Duo1 PF08651.10 EAN32071.1 - 4 7.3 10.7 5.9 6.7 0.3 3.3 4 0 0 4 4 4 0 DASH complex subunit Duo1 Baculo_PEP_C PF04513.12 EAN32071.1 - 7.4 6.6 10.8 1.1 9.3 5.9 2.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus E1_dh PF00676.20 EAN32072.1 - 3e-80 269.4 0.2 6.2e-80 268.3 0.2 1.4 1 1 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EAN32072.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase RRM_1 PF00076.22 EAN32077.1 - 1.6e-11 43.9 0.1 1.8e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAN32077.1 - 0.091 12.6 0.0 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif SDF PF00375.18 EAN32078.1 - 2.7e-21 76.1 16.6 3.5e-21 75.7 16.6 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DEAD PF00270.29 EAN32080.1 - 5.1e-22 78.5 0.0 1.3e-21 77.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN32080.1 - 2.7e-20 72.8 0.3 1.8e-19 70.1 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN32080.1 - 2.4e-07 30.9 0.0 5.5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NAT PF04768.13 EAN32080.1 - 0.022 14.5 0.0 28 4.3 0.0 3.2 2 1 1 3 3 3 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase YEATS PF03366.16 EAN32081.1 - 5.6e-25 87.1 0.0 9.3e-25 86.4 0.0 1.4 1 0 0 1 1 1 1 YEATS family V_ATPase_I PF01496.19 EAN32084.1 - 3.4e-245 815.8 6.3 3.8e-245 815.7 6.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Fibrillarin PF01269.17 EAN32084.1 - 0.12 11.4 0.3 0.26 10.4 0.3 1.5 1 0 0 1 1 1 0 Fibrillarin MMR_HSR1 PF01926.23 EAN32085.1 - 2e-18 66.6 0.0 3.7e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAN32085.1 - 4.4e-06 26.9 2.5 0.066 13.3 0.0 2.9 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 EAN32085.1 - 3.7e-05 23.2 0.0 6.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 EAN32085.1 - 0.00022 20.6 0.0 0.00044 19.6 0.0 1.4 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 EAN32085.1 - 0.00043 19.9 0.0 0.0071 15.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EAN32085.1 - 0.001 18.6 0.0 0.0025 17.4 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EAN32085.1 - 0.0033 16.9 1.7 0.0084 15.6 0.0 2.3 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EAN32085.1 - 0.0035 17.3 0.5 0.016 15.1 0.0 2.3 3 0 0 3 3 3 1 RsgA GTPase AAA_15 PF13175.6 EAN32085.1 - 0.0067 16.2 3.9 0.051 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 EAN32085.1 - 0.0071 16.6 0.0 0.017 15.3 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF3629 PF12302.8 EAN32085.1 - 0.014 14.9 1.8 0.022 14.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3629) RNA_helicase PF00910.22 EAN32085.1 - 0.022 15.1 0.0 0.055 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EAN32085.1 - 0.034 13.6 0.8 0.14 11.7 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region Ras PF00071.22 EAN32085.1 - 0.071 12.7 0.9 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Ras family ATP_bind_1 PF03029.17 EAN32085.1 - 0.088 12.6 1.8 3.4 7.4 0.0 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Gly_acyl_tr_C PF08444.10 EAN32085.1 - 0.15 12.3 0.1 2.3 8.5 0.0 2.7 2 2 1 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF4477 PF14780.6 EAN32085.1 - 0.17 11.5 0.5 0.32 10.6 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Ribosomal_L3 PF00297.22 EAN32086.1 - 2.7e-10 39.8 5.1 8.4e-08 31.6 3.4 2.9 2 1 0 2 2 2 1 Ribosomal protein L3 CytadhesinP1 PF12378.8 EAN32087.1 - 0.0067 16.6 0.3 0.014 15.6 0.3 1.5 1 0 0 1 1 1 1 Trypsin-sensitive surface-exposed protein RRM_1 PF00076.22 EAN32087.1 - 0.088 12.6 0.1 0.77 9.6 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleoporin2 PF04096.14 EAN32088.1 - 1.7e-30 106.1 0.0 4e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EAN32088.1 - 6.6e-11 42.9 273.0 0.00069 20.4 45.0 8.8 2 2 5 7 7 7 3 Nucleoporin FG repeat region Ribosomal_S21e PF01249.18 EAN32089.1 - 3.2e-33 113.7 0.0 3.6e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Img2 PF05046.14 EAN32090.1 - 2.2e-21 75.9 0.0 2.9e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) GP41 PF00517.17 EAN32090.1 - 0.095 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Creatinase_N_2 PF16189.5 EAN32091.1 - 7.3e-45 153.0 0.3 3.8e-44 150.6 0.0 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EAN32091.1 - 1.2e-39 136.2 0.0 2.1e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EAN32091.1 - 2.2e-27 96.3 1.3 2.3e-23 83.3 0.0 2.7 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EAN32091.1 - 4.6e-19 68.2 0.1 1e-18 67.1 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 DRE2_N PF16803.5 EAN32091.1 - 0.011 16.0 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus eIF-3c_N PF05470.12 EAN32092.1 - 2.2e-95 320.2 45.4 1.4e-93 314.3 45.4 2.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EAN32092.1 - 7.6e-10 39.3 7.4 1.2e-09 38.6 0.1 3.5 4 0 0 4 4 4 1 PCI domain DUF924 PF06041.11 EAN32092.1 - 0.039 14.1 1.5 10 6.2 0.3 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF924) tRNA-synt_1 PF00133.22 EAN32093.1 - 3e-189 630.2 0.0 3.4e-188 626.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EAN32093.1 - 1.8e-38 131.9 0.1 3.5e-38 130.9 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EAN32093.1 - 1.9e-16 59.8 1.0 8.3e-07 28.1 0.0 4.2 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EAN32093.1 - 8.5e-08 31.9 0.1 4.4e-07 29.6 0.0 2.1 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 EAN32093.1 - 2.6e-06 27.6 0.5 6.1e-06 26.4 0.5 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1b PF00579.25 EAN32093.1 - 0.014 14.7 0.1 0.048 13.0 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 EAN32093.1 - 0.067 12.1 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (K) Rad9 PF04139.13 EAN32098.1 - 1.1e-18 67.6 1.0 1.1e-18 67.6 1.0 2.4 2 0 0 2 2 2 1 Rad9 RimM PF01782.18 EAN32098.1 - 4.7e-17 62.0 0.0 2.4e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 RimM N-terminal domain PCNA_N PF00705.18 EAN32098.1 - 0.0056 16.4 0.9 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain zf-met PF12874.7 EAN32098.1 - 0.032 14.6 1.4 0.085 13.3 1.4 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EAN32098.1 - 0.069 13.6 0.4 0.25 11.9 0.4 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type Peptidase_M1 PF01433.20 EAN32098.1 - 0.27 10.8 2.8 1.1 8.8 0.5 2.3 2 0 0 2 2 2 0 Peptidase family M1 domain zf-C2H2_jaz PF12171.8 EAN32098.1 - 1.1 9.6 7.5 1.2 9.5 5.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Phage_int_SAM_1 PF02899.17 EAN32099.1 - 0.11 12.8 0.0 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Cyclin_N PF00134.23 EAN32100.1 - 0.004 16.9 0.2 0.18 11.6 0.0 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAN32100.1 - 0.044 13.9 0.1 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 Cyclin, C-terminal domain Ribosomal_S2 PF00318.20 EAN32101.1 - 3.9e-29 101.4 0.3 7.5e-16 58.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Clathrin PF00637.20 EAN32101.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Region in Clathrin and VPS PPI_Ypi1 PF07491.11 EAN32102.1 - 6.7e-14 51.5 6.9 7e-14 51.4 6.2 1.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor DNA_photolyase PF00875.18 EAN32102.1 - 0.072 13.1 0.0 0.085 12.9 0.0 1.0 1 0 0 1 1 1 0 DNA photolyase Surp PF01805.20 EAN32104.1 - 7.8e-15 54.6 0.0 2.1e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 EAN32104.1 - 1.4e-13 50.5 0.0 2.7e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EAN32104.1 - 3.2e-08 34.3 1.2 1e-07 32.6 1.2 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 EAN32104.1 - 2.7e-05 24.2 2.1 7.1e-05 22.8 2.1 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Xpo1 PF08389.12 EAN32104.1 - 1.2 9.2 4.7 1.1 9.3 2.4 2.2 2 1 0 2 2 2 0 Exportin 1-like protein Put_DNA-bind_N PF06971.13 EAN32104.1 - 9.5 6.3 6.0 21 5.2 0.0 3.5 4 0 0 4 4 4 0 Putative DNA-binding protein N-terminus Ribosomal_S27 PF01599.19 EAN32105.1 - 2.5e-21 75.6 2.2 2.5e-21 75.6 2.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.23 EAN32105.1 - 0.017 14.8 0.2 0.042 13.6 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin family zf-U1 PF06220.12 EAN32106.1 - 4.4e-05 23.2 2.5 0.00011 21.9 2.5 1.7 1 0 0 1 1 1 1 U1 zinc finger WW PF00397.26 EAN32106.1 - 0.00026 21.0 0.6 0.0023 18.0 0.7 2.4 2 0 0 2 2 2 1 WW domain NUDIX PF00293.28 EAN32108.1 - 4.1e-09 36.6 0.0 7.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SAC3_GANP PF03399.16 EAN32109.1 - 2.6e-39 135.4 3.7 2.6e-39 135.4 3.7 3.2 2 1 0 2 2 2 1 SAC3/GANP family DUF2205 PF10224.9 EAN32109.1 - 0.025 14.6 0.2 0.19 11.8 0.0 2.6 2 0 0 2 2 2 0 Short coiled-coil protein DCP1 PF06058.13 EAN32110.1 - 1.3e-26 92.8 0.5 2.9e-26 91.7 0.1 1.8 2 0 0 2 2 2 1 Dcp1-like decapping family DUF1387 PF07139.11 EAN32110.1 - 0.052 13.3 10.2 0.083 12.6 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TFIIE-A_C PF11521.8 EAN32110.1 - 9 6.7 7.8 5.2 7.4 0.3 2.4 1 1 1 2 2 2 0 C-terminal general transcription factor TFIIE alpha NACHT PF05729.12 EAN32111.1 - 8.8e-05 22.5 0.1 0.0008 19.4 0.0 2.3 2 1 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 EAN32111.1 - 0.0006 19.4 1.0 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EAN32111.1 - 0.003 17.9 0.1 0.04 14.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 EAN32111.1 - 0.0033 17.4 0.1 0.034 14.0 0.0 2.4 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 EAN32111.1 - 0.0034 17.2 0.0 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EAN32111.1 - 0.011 16.3 0.1 0.06 13.9 0.0 2.2 3 0 0 3 3 3 0 ABC transporter TsaE PF02367.17 EAN32111.1 - 0.026 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EAN32111.1 - 0.026 14.9 0.0 0.088 13.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EAN32111.1 - 0.032 14.1 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.6 EAN32111.1 - 0.038 14.3 0.0 0.084 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAN32111.1 - 0.042 14.2 0.0 0.076 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EAN32111.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glycos_transf_1 PF00534.20 EAN32112.1 - 2e-28 99.1 0.0 2.8e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EAN32112.1 - 3.2e-22 79.4 0.0 5.9e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 PIGA PF08288.12 EAN32112.1 - 5.5e-14 52.5 2.5 6.8e-14 52.2 0.4 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EAN32112.1 - 1.1e-13 51.5 2.7 1e-09 38.6 0.2 2.7 2 1 1 3 3 3 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EAN32112.1 - 1.1e-07 32.4 0.1 5.4e-05 23.7 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EAN32112.1 - 0.0015 18.6 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EAN32112.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Imm8 PF15586.6 EAN32112.1 - 0.033 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 8 PCI PF01399.27 EAN32115.1 - 5.5e-18 65.4 2.5 6.1e-18 65.3 0.8 2.0 2 0 0 2 2 2 1 PCI domain RPN6_N PF18055.1 EAN32115.1 - 2.2e-09 37.7 0.1 7.1e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain DDRGK PF09756.9 EAN32115.1 - 0.015 14.9 0.2 0.037 13.6 0.2 1.6 1 0 0 1 1 1 0 DDRGK domain TFIID-31kDa PF02291.15 EAN32116.1 - 0.095 12.8 0.2 0.14 12.2 0.2 1.3 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DER1 PF04511.15 EAN32117.1 - 2e-34 119.2 13.9 2.4e-34 119.0 13.9 1.0 1 0 0 1 1 1 1 Der1-like family AzlD PF05437.12 EAN32117.1 - 0.0025 17.9 1.3 0.0025 17.9 1.3 2.0 3 0 0 3 3 3 1 Branched-chain amino acid transport protein (AzlD) DUF155 PF02582.14 EAN32118.1 - 3.5e-07 30.5 0.3 3.5e-07 30.5 0.3 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 RRM_1 PF00076.22 EAN32119.1 - 9.7e-28 95.8 0.3 9.4e-13 47.8 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAN32119.1 - 1.1e-07 31.9 0.1 0.0059 16.7 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM PF05172.13 EAN32119.1 - 0.073 13.0 0.1 7.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EAN32119.1 - 0.078 13.0 0.1 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Zip PF02535.22 EAN32119.1 - 1.8 7.7 7.2 2.9 7.0 7.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter UCH PF00443.29 EAN32120.1 - 2e-39 135.6 1.7 2.9e-39 135.1 1.7 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EAN32120.1 - 3.4e-09 36.3 0.0 1.1e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family UCH_1 PF13423.6 EAN32120.1 - 0.00037 20.2 10.1 0.0032 17.1 5.3 2.5 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-G-binding_N PF07299.11 EAN32121.1 - 0.065 13.8 0.6 0.079 13.5 0.6 1.1 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal CDC45 PF02724.14 EAN32122.1 - 0.38 9.0 6.4 0.39 9.0 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M24 PF00557.24 EAN32123.1 - 2.6e-35 122.0 0.0 3.3e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_L26 PF16906.5 EAN32124.1 - 5.2e-36 123.0 7.6 6.6e-36 122.6 7.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EAN32124.1 - 1.6e-07 31.0 0.6 3.5e-07 29.9 0.6 1.7 1 0 0 1 1 1 1 KOW motif DUF5301 PF17225.3 EAN32124.1 - 0.025 15.0 0.1 0.043 14.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5300) ANAPC4_WD40 PF12894.7 EAN32125.1 - 1.3e-05 25.3 0.1 0.00048 20.4 0.1 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAN32125.1 - 0.19 12.6 12.4 0.53 11.2 0.2 4.2 4 1 0 4 4 4 0 WD domain, G-beta repeat DEAD PF00270.29 EAN32127.1 - 1.5e-43 148.6 1.5 3.9e-43 147.3 0.3 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN32127.1 - 1.6e-09 38.1 8.5 0.007 16.7 0.0 4.2 2 2 1 4 4 4 3 Helicase conserved C-terminal domain AAA_22 PF13401.6 EAN32127.1 - 0.012 15.9 1.5 4.5 7.6 0.0 3.1 3 1 0 3 3 3 0 AAA domain DUF4318 PF14201.6 EAN32127.1 - 0.053 14.0 0.5 0.76 10.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4318) NEMP PF10225.9 EAN32127.1 - 0.3 10.7 4.0 0.6 9.7 4.0 1.5 1 0 0 1 1 1 0 NEMP family tRNA-synt_1b PF00579.25 EAN32129.1 - 4.9e-52 177.1 0.8 6.4e-52 176.7 0.8 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 EAN32129.1 - 0.083 11.8 0.2 0.56 9.1 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) G10 PF01125.17 EAN32130.1 - 0.14 11.9 6.4 0.29 10.9 0.6 2.8 2 1 0 2 2 2 0 G10 protein Pkinase PF00069.25 EAN32131.1 - 6e-52 176.6 0.0 1.2e-51 175.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32131.1 - 5.4e-27 94.7 0.0 7.4e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAN32131.1 - 1.6e-05 24.4 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SpoIIM PF01944.17 EAN32133.1 - 0.049 13.7 0.1 0.049 13.7 0.1 1.8 2 0 0 2 2 2 0 Stage II sporulation protein M DUF2883 PF11097.8 EAN32133.1 - 0.11 12.6 0.2 11 6.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2883) P63C PF10546.9 EAN32133.1 - 0.13 12.8 1.0 0.45 11.1 0.1 2.2 2 0 0 2 2 2 0 P63C domain Sid-5 PF17204.3 EAN32133.1 - 1.5 9.0 6.5 0.25 11.5 0.9 2.5 3 0 0 3 3 3 0 Sid-5 family RSN1_7TM PF02714.15 EAN32134.1 - 5.8e-15 55.3 21.3 9.8e-15 54.6 21.3 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate CC2-LZ PF16516.5 EAN32135.1 - 0.0039 17.5 9.5 0.092 13.1 4.2 2.1 2 0 0 2 2 2 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ADIP PF11559.8 EAN32135.1 - 0.01 15.9 8.3 0.045 13.8 2.8 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.9 EAN32135.1 - 0.013 15.8 4.9 0.013 15.8 4.9 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF641 PF04859.12 EAN32135.1 - 0.018 15.4 3.8 1.6 9.0 0.1 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Cep57_MT_bd PF06657.13 EAN32135.1 - 0.047 14.1 8.0 1.7 9.1 0.2 2.7 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.8 EAN32135.1 - 0.085 13.1 10.6 0.16 12.2 4.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 EAN32135.1 - 0.11 11.4 11.0 0.54 9.1 3.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein HAP1_N PF04849.13 EAN32135.1 - 0.17 11.0 9.6 0.28 10.3 2.1 2.0 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF16 PF01519.16 EAN32135.1 - 0.18 12.3 8.0 3 8.4 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 EAN32135.1 - 0.34 10.9 7.4 2.1 8.4 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 EAN32135.1 - 0.49 10.2 6.5 2.7 7.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) P4Ha_N PF08336.11 EAN32135.1 - 1 9.4 8.3 5.3 7.1 1.6 2.2 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region APG6_N PF17675.1 EAN32135.1 - 1.1 9.8 9.9 0.27 11.8 4.4 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region FlxA PF14282.6 EAN32135.1 - 1.9 8.5 10.5 0.51 10.4 4.1 2.3 2 1 0 2 2 2 0 FlxA-like protein FliD_N PF02465.18 EAN32135.1 - 2.3 8.9 6.3 7 7.4 1.8 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Atg14 PF10186.9 EAN32135.1 - 2.4 7.2 12.4 1.3 8.0 2.9 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Vps26 PF03643.15 EAN32136.1 - 7.3e-92 307.3 1.3 8.2e-92 307.1 1.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 ANAPC3 PF12895.7 EAN32137.1 - 0.0014 18.8 1.4 0.0056 16.9 1.4 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 EAN32137.1 - 0.0016 17.5 0.1 0.18 10.8 0.0 2.4 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.6 EAN32137.1 - 0.0071 16.7 1.4 0.024 15.0 0.2 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAN32137.1 - 0.012 15.6 0.2 1.4 9.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAN32137.1 - 0.097 12.5 1.5 1.1 9.2 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C_2 PF13307.6 EAN32138.1 - 7.4e-49 166.2 0.1 3.7e-48 163.9 0.0 2.3 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 EAN32138.1 - 6e-46 156.3 0.1 1.9e-45 154.6 0.0 1.9 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 EAN32138.1 - 2.2e-06 27.8 0.5 0.00078 19.5 0.1 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EAN32138.1 - 0.00051 19.9 0.5 0.0026 17.6 0.5 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 EAN32138.1 - 0.047 13.1 0.8 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein LsmAD PF06741.13 EAN32140.1 - 1.6e-09 38.2 0.4 1.6e-09 38.2 0.4 3.5 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.6 EAN32140.1 - 0.00032 20.8 0.0 0.00079 19.5 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 EAN32140.1 - 0.0012 18.4 0.0 0.0035 17.0 0.0 1.7 1 0 0 1 1 1 1 LSM domain PAM2 PF07145.15 EAN32140.1 - 0.014 15.1 0.5 0.014 15.1 0.5 2.1 2 0 0 2 2 2 0 Ataxin-2 C-terminal region AlphaC_C PF17480.2 EAN32140.1 - 0.15 12.1 2.1 0.37 10.8 2.1 1.6 1 0 0 1 1 1 0 AlphaC C-terminal MMR_HSR1 PF01926.23 EAN32141.1 - 4.7e-19 68.6 0.0 1.1e-18 67.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAN32141.1 - 2.6e-08 34.1 0.3 0.0015 18.6 0.6 2.4 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 EAN32141.1 - 8.2e-07 28.7 0.0 7.1e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EAN32141.1 - 1.7e-05 24.3 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 EAN32141.1 - 0.00027 20.5 0.0 1.8 8.0 0.0 3.1 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain Arf PF00025.21 EAN32141.1 - 0.00035 20.1 0.0 0.011 15.2 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAN32141.1 - 0.00053 19.9 0.3 1.4 8.8 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EAN32141.1 - 0.0034 16.6 0.2 1.7 7.7 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit cobW PF02492.19 EAN32141.1 - 0.0047 16.5 0.0 0.085 12.4 0.0 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EAN32141.1 - 0.059 13.6 0.0 0.49 10.6 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EAN32141.1 - 0.068 12.5 0.1 0.41 10.0 0.0 2.0 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAN32141.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.18 EAN32141.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ubiq_cyt_C_chap PF03981.12 EAN32142.1 - 0.0022 18.1 0.1 0.003 17.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone ACDC PF14733.6 EAN32143.1 - 1.5e-22 79.7 4.6 2.8e-22 78.8 4.6 1.5 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 EAN32143.1 - 4.9e-18 65.1 1.1 9.2e-18 64.2 1.1 1.5 1 0 0 1 1 1 1 AP2 domain Pkinase PF00069.25 EAN32144.1 - 3.1e-42 144.7 0.0 2.5e-40 138.5 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32144.1 - 1.1e-15 57.7 0.0 2e-12 47.0 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAN32144.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Trm112p PF03966.16 EAN32145.1 - 1.4e-12 48.0 0.1 1.9e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein DUF2067 PF09840.9 EAN32145.1 - 0.041 13.5 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) zf-UDP PF14569.6 EAN32145.1 - 0.042 14.0 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger DiS_P_DiS PF06750.13 EAN32145.1 - 0.066 13.3 0.3 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain PRP38 PF03371.15 EAN32146.1 - 2.5e-05 24.2 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 PRP38 family CDC45 PF02724.14 EAN32146.1 - 0.0015 16.9 6.8 0.0018 16.7 6.8 1.1 1 0 0 1 1 1 1 CDC45-like protein NPR3 PF03666.13 EAN32146.1 - 3.1 6.5 12.5 3.8 6.2 12.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 EAN32146.1 - 5.3 5.7 7.6 7.1 5.3 7.6 1.1 1 0 0 1 1 1 0 Presenilin PRP38 PF03371.15 EAN32147.1 - 4.1e-35 121.2 1.9 6.3e-35 120.6 1.9 1.3 1 0 0 1 1 1 1 PRP38 family AbiTii PF18864.1 EAN32147.1 - 0.1 12.7 0.4 0.14 12.3 0.4 1.3 1 0 0 1 1 1 0 AbiTii Prominin PF05478.11 EAN32148.1 - 0.025 12.6 9.7 0.42 8.5 5.0 2.1 2 0 0 2 2 2 0 Prominin PAPS_reduct PF01507.19 EAN32148.1 - 0.061 13.4 0.6 0.1 12.6 0.3 1.5 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Sec20 PF03908.13 EAN32148.1 - 0.085 12.8 5.8 0.13 12.2 0.6 3.0 1 1 2 3 3 3 0 Sec20 SNARE PF05739.19 EAN32148.1 - 0.55 10.3 4.1 2.4 8.2 4.1 2.2 1 1 0 1 1 1 0 SNARE domain Fibrillarin PF01269.17 EAN32149.1 - 6.5e-103 342.7 0.0 8.3e-103 342.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EAN32149.1 - 0.00024 20.9 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 EAN32149.1 - 0.013 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F LCCL PF03815.19 EAN32150.1 - 1.2e-85 281.8 10.2 2.1e-27 95.0 0.3 5.0 3 1 1 4 4 4 4 LCCL domain SRCR PF00530.18 EAN32150.1 - 7e-36 122.8 14.7 6.8e-18 65.0 3.0 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain PLAT PF01477.23 EAN32150.1 - 2.5e-14 53.9 1.4 4.7e-13 49.7 0.0 3.0 3 0 0 3 3 3 1 PLAT/LH2 domain Rxt3 PF08642.10 EAN32150.1 - 5.4e-11 43.4 0.3 0.0041 17.9 0.0 4.5 5 0 0 5 5 5 2 Histone deacetylation protein Rxt3 Laminin_G_3 PF13385.6 EAN32150.1 - 7.7e-05 22.9 0.0 0.00022 21.4 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SRCR_2 PF15494.6 EAN32150.1 - 0.00038 20.9 9.5 0.01 16.4 0.7 3.0 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 EAN32150.1 - 0.023 15.2 0.9 9.4 6.8 0.1 2.7 2 0 0 2 2 2 0 Hepsin, SRCR domain Radical_SAM PF04055.21 EAN32151.1 - 1.9e-10 41.4 0.0 2.6e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EAN32151.1 - 0.00031 20.9 0.0 0.00062 19.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 EAN32151.1 - 0.046 14.0 0.0 0.071 13.4 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF3273 PF11677.8 EAN32152.1 - 6.2e-109 363.4 5.4 7.6e-109 363.1 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Metallophos_2 PF12850.7 EAN32153.1 - 3.7e-18 66.3 0.0 4.7e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EAN32153.1 - 0.014 15.9 0.1 2.2 8.7 0.1 2.4 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase AAA_2 PF07724.14 EAN32154.1 - 5.5e-49 166.6 1.4 4.3e-48 163.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EAN32154.1 - 1.5e-23 82.7 0.2 5.3e-23 80.9 0.2 1.9 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 EAN32154.1 - 5e-23 82.0 0.0 1.1e-10 42.0 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAN32154.1 - 5.1e-19 68.6 0.0 2e-13 50.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 EAN32154.1 - 5.4e-17 61.6 0.2 1.7e-16 60.1 0.2 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 EAN32154.1 - 7.5e-14 52.2 0.2 4.4e-05 23.8 0.0 4.3 4 1 1 5 5 3 2 AAA domain Clp_N PF02861.20 EAN32154.1 - 6.3e-12 45.4 0.0 5.9e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 EAN32154.1 - 1.2e-10 42.1 0.5 0.00036 21.0 0.1 3.9 4 1 0 4 4 2 2 AAA ATPase domain Sigma54_activat PF00158.26 EAN32154.1 - 1.1e-08 34.9 0.0 8.9e-06 25.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 EAN32154.1 - 4.7e-07 29.5 0.0 0.017 14.7 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 EAN32154.1 - 6e-07 29.1 0.1 0.014 14.7 0.0 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EAN32154.1 - 1.2e-06 27.9 0.1 0.001 18.4 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin RuvB_N PF05496.12 EAN32154.1 - 2.9e-06 27.1 0.0 0.17 11.6 0.0 3.7 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EAN32154.1 - 6.7e-06 26.4 1.5 0.21 12.0 0.7 3.8 2 1 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 EAN32154.1 - 7e-06 26.6 0.0 0.0074 16.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EAN32154.1 - 4.1e-05 23.1 0.0 0.047 13.1 0.0 3.3 2 1 0 2 2 2 1 Bacterial TniB protein AAA_3 PF07726.11 EAN32154.1 - 7.1e-05 22.7 0.0 0.076 12.9 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAN32154.1 - 9.1e-05 22.6 0.0 0.076 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta2 PF13177.6 EAN32154.1 - 0.00012 22.0 0.2 0.91 9.3 0.0 3.6 3 0 0 3 3 3 2 DNA polymerase III, delta subunit IstB_IS21 PF01695.17 EAN32154.1 - 0.00015 21.6 0.0 0.33 10.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 EAN32154.1 - 0.00018 20.8 1.0 0.16 11.2 0.0 3.5 4 0 0 4 4 4 1 TIP49 P-loop domain AAA_30 PF13604.6 EAN32154.1 - 0.00049 19.9 0.0 2 8.1 0.1 3.4 3 1 0 3 3 3 2 AAA domain Torsin PF06309.11 EAN32154.1 - 0.0006 19.9 0.0 0.0041 17.2 0.0 2.2 2 0 0 2 2 2 1 Torsin MMR_HSR1 PF01926.23 EAN32154.1 - 0.0015 18.6 0.0 0.69 10.0 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase MCM PF00493.23 EAN32154.1 - 0.0015 17.7 0.5 3 6.9 0.0 3.5 3 1 0 3 3 3 1 MCM P-loop domain ABC_tran PF00005.27 EAN32154.1 - 0.0032 18.0 0.2 1.3 9.5 0.0 2.9 2 0 0 2 2 2 1 ABC transporter DUF815 PF05673.13 EAN32154.1 - 0.0034 16.6 0.2 1.4 8.1 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF815) ResIII PF04851.15 EAN32154.1 - 0.0037 17.3 0.4 1.1 9.2 0.0 3.9 3 1 1 4 4 3 1 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 EAN32154.1 - 0.0049 16.8 0.0 4 7.3 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase NTPase_1 PF03266.15 EAN32154.1 - 0.0056 16.6 0.1 1.9 8.4 0.0 3.4 3 0 0 3 3 3 1 NTPase AAA_19 PF13245.6 EAN32154.1 - 0.008 16.5 3.3 0.6 10.4 0.6 4.1 4 1 0 4 4 2 1 AAA domain AAA_29 PF13555.6 EAN32154.1 - 0.0092 15.7 0.0 6 6.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 EAN32154.1 - 0.013 15.8 0.0 3 8.1 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_11 PF13086.6 EAN32154.1 - 0.016 15.0 3.0 3.3 7.4 0.0 3.2 2 1 1 3 3 3 0 AAA domain KTI12 PF08433.10 EAN32154.1 - 0.02 14.3 0.0 0.27 10.7 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_24 PF13479.6 EAN32154.1 - 0.023 14.5 0.0 2.9 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EAN32154.1 - 0.028 14.4 0.0 1.8 8.6 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EAN32154.1 - 0.042 13.8 0.0 0.41 10.5 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 EAN32154.1 - 0.054 13.4 0.0 0.46 10.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 EAN32154.1 - 0.11 12.9 0.3 11 6.4 0.1 3.1 2 1 0 2 2 2 0 AAA domain PPR PF01535.20 EAN32155.1 - 1.6e-07 31.1 12.5 0.1 12.9 0.0 6.3 7 0 0 7 7 7 3 PPR repeat PPR_2 PF13041.6 EAN32155.1 - 1.2e-06 28.6 9.0 0.071 13.3 0.0 5.5 5 1 0 5 5 5 2 PPR repeat family PPR_long PF17177.4 EAN32155.1 - 4.1e-06 26.3 7.0 0.045 13.1 0.0 4.2 2 2 3 5 5 5 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EAN32155.1 - 0.00015 21.8 5.6 0.031 14.4 0.1 4.7 2 2 2 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 EAN32155.1 - 0.0064 16.2 0.1 0.37 10.5 0.0 3.2 3 0 0 3 3 3 1 PPR repeat FeS_assembly_P PF01883.19 EAN32156.1 - 1.7e-08 34.5 0.0 2.5e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein TPT PF03151.16 EAN32157.1 - 3.2e-09 36.5 12.8 4.3e-09 36.1 12.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EAN32157.1 - 2.3e-07 31.1 24.6 0.00054 20.1 6.5 2.6 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EAN32157.1 - 0.0024 17.2 21.0 0.0051 16.1 15.1 2.3 2 1 0 2 2 2 2 Purine nucleobase transmembrane transport Bromodomain PF00439.25 EAN32158.1 - 3.2e-10 40.0 0.4 1.4e-09 37.8 0.4 2.3 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 EAN32158.1 - 0.00028 20.7 88.5 0.0018 18.1 9.7 9.0 9 0 0 9 9 9 5 PHD-finger FYRN PF05964.14 EAN32158.1 - 0.0049 16.7 0.8 0.12 12.2 0.0 2.8 2 0 0 2 2 2 1 F/Y-rich N-terminus CutA1 PF03091.15 EAN32158.1 - 1.2 9.1 3.6 33 4.4 0.8 3.5 3 0 0 3 3 3 0 CutA1 divalent ion tolerance protein SET PF00856.28 EAN32159.1 - 9.4e-21 74.9 0.4 3.8e-20 73.0 0.4 1.9 1 1 0 1 1 1 1 SET domain AF0941-like PF14591.6 EAN32159.1 - 0.14 12.8 0.0 0.52 10.9 0.0 1.9 2 0 0 2 2 2 0 AF0941-like Ubie_methyltran PF01209.18 EAN32160.1 - 2.8e-77 259.2 0.3 1e-64 218.1 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EAN32160.1 - 5.1e-16 59.1 0.0 1.1e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAN32160.1 - 7.1e-16 58.7 0.0 8e-15 55.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAN32160.1 - 6.5e-10 39.0 0.0 2.1e-09 37.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAN32160.1 - 1.9e-09 38.1 0.0 4.4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAN32160.1 - 1.4e-05 25.0 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EAN32160.1 - 0.006 16.4 0.0 0.035 13.9 0.0 2.1 1 1 0 2 2 2 1 Hypothetical methyltransferase Peptidase_C78 PF07910.13 EAN32161.1 - 4.5e-44 150.5 2.0 7.8e-44 149.7 1.2 1.8 2 0 0 2 2 2 1 Peptidase family C78 Peptidase_C54 PF03416.19 EAN32161.1 - 0.0062 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C54 NARP1 PF12569.8 EAN32161.1 - 0.037 12.9 1.2 0.081 11.8 1.3 1.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 UPF0020 PF01170.18 EAN32162.1 - 3.3e-11 43.2 0.0 8.8e-11 41.8 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 DUF4205 PF13898.6 EAN32163.1 - 1.6e-54 185.1 0.4 2.8e-42 144.9 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4205) WD40 PF00400.32 EAN32164.1 - 3.2e-12 46.7 6.2 0.00033 21.4 0.2 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN32164.1 - 4.2e-12 46.2 0.2 0.0076 16.5 0.1 4.1 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EAN32164.1 - 7.1e-11 42.5 0.5 1.8e-10 41.2 0.5 1.8 1 0 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 EAN32164.1 - 1.8e-05 24.2 0.3 6.1e-05 22.5 0.1 2.1 1 1 0 1 1 1 1 WD40-like domain eIF2A PF08662.11 EAN32164.1 - 0.011 15.6 2.0 0.084 12.7 0.1 2.9 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EAN32164.1 - 0.06 12.7 0.1 0.21 10.9 0.0 1.9 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal SET PF00856.28 EAN32165.1 - 4.1e-21 76.1 6.0 1.3e-20 74.4 1.1 3.4 2 1 0 2 2 2 1 SET domain C1_1 PF00130.22 EAN32165.1 - 0.0039 17.0 6.2 0.0039 17.0 6.2 5.1 5 1 1 6 6 6 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AWS PF17907.1 EAN32165.1 - 0.014 15.4 8.4 0.014 15.4 8.4 3.5 5 0 0 5 5 5 0 AWS domain PolC_DP2 PF03833.13 EAN32166.1 - 0.082 10.8 4.1 0.1 10.5 4.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DNA_pol_B_exo1 PF03104.19 EAN32167.1 - 1.8e-47 162.1 5.6 5.9e-47 160.4 5.6 2.0 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EAN32167.1 - 6.2e-12 45.0 2.3 2.5e-08 33.1 0.1 3.0 3 0 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EAN32167.1 - 3.4e-07 30.2 0.6 2.3e-06 27.4 0.6 2.3 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EAN32167.1 - 6.9e-05 22.9 2.2 0.00016 21.7 0.1 2.9 3 1 0 3 3 3 1 RNase_H superfamily Fmp27_SW PF10305.9 EAN32167.1 - 0.43 11.3 5.6 0.12 13.1 0.3 2.9 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain Retrotrans_gag PF03732.17 EAN32167.1 - 0.98 9.7 6.6 0.12 12.7 0.5 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein DUF1744 PF08490.12 EAN32168.1 - 2.8e-19 69.0 0.9 4.9e-19 68.2 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) CPW_WPC PF09717.10 EAN32170.1 - 1.9e-26 92.8 15.6 6.7e-16 59.0 10.1 2.5 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) PRESAN PF09687.10 EAN32170.1 - 0.29 11.7 8.5 0.053 14.1 4.2 2.0 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Pkinase PF00069.25 EAN32172.1 - 6.1e-70 235.6 0.0 7.5e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32172.1 - 9.6e-35 120.1 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAN32172.1 - 5.6e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAN32172.1 - 6.5e-05 22.0 0.1 9e-05 21.6 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAN32172.1 - 0.0078 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAN32172.1 - 0.024 14.6 0.1 0.079 12.9 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family MAGP PF05507.11 EAN32172.1 - 0.042 14.3 0.3 0.081 13.3 0.3 1.3 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) 5_nucleotid PF05761.14 EAN32172.1 - 0.096 11.6 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 5' nucleotidase family FAINT PF04385.15 EAN32173.1 - 2.3e-08 34.0 38.8 0.00036 20.5 7.4 6.3 5 1 0 5 5 5 3 Domain of unknown function, DUF529 Sushi PF00084.20 EAN32173.1 - 0.09 13.4 0.2 0.86 10.3 0.0 2.5 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) FAINT PF04385.15 EAN32174.1 - 1.1e-20 73.4 26.0 9.5e-05 22.4 1.2 5.7 5 0 0 5 5 5 5 Domain of unknown function, DUF529 DEAD PF00270.29 EAN32175.1 - 1.5e-45 155.1 0.0 2.7e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN32175.1 - 8.7e-24 84.0 0.8 2.6e-23 82.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EAN32175.1 - 5e-18 65.1 0.4 1.2e-17 63.8 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EAN32175.1 - 0.004 17.2 0.4 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.12 EAN32175.1 - 0.01 15.7 0.4 0.031 14.2 0.0 2.1 2 1 0 2 2 2 0 NACHT domain OCRE PF17780.1 EAN32176.1 - 3.1e-07 30.3 0.6 6.3e-07 29.3 0.6 1.5 1 0 0 1 1 1 1 OCRE domain zf-RanBP PF00641.18 EAN32176.1 - 3.5e-06 26.2 1.1 7.2e-06 25.2 1.1 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others TackOD1 PF18551.1 EAN32176.1 - 0.051 13.2 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Vps36-NZF-N PF16988.5 EAN32176.1 - 2.6 7.5 7.6 0.94 8.9 2.1 3.0 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Tfb4 PF03850.14 EAN32177.1 - 4.6e-28 98.5 0.0 5.6e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 ER_lumen_recept PF00810.18 EAN32178.1 - 3.4e-47 161.0 13.4 5.6e-47 160.3 13.4 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EAN32178.1 - 0.22 11.3 0.2 0.22 11.3 0.2 4.3 3 1 2 5 5 5 0 PQ loop repeat Hydrolase_4 PF12146.8 EAN32179.1 - 7.3e-06 25.4 0.0 0.0019 17.5 0.0 2.9 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Romo1 PF10247.9 EAN32180.1 - 6.9e-17 61.6 8.0 1.1e-16 60.9 8.0 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Proteasome PF00227.26 EAN32181.1 - 2.8e-58 196.6 0.0 3.5e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAN32181.1 - 1.9e-13 49.8 0.2 3.4e-13 49.0 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ssl1 PF04056.14 EAN32181.1 - 0.02 14.7 0.1 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Ssl1-like Proteasome PF00227.26 EAN32182.1 - 1.7e-57 194.0 0.2 2.3e-57 193.5 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAN32182.1 - 4e-14 52.0 0.0 8.3e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-C3HC4_2 PF13923.6 EAN32183.1 - 2.3e-06 27.3 13.7 4.4e-06 26.4 13.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAN32183.1 - 4.2e-06 26.5 15.5 8.2e-06 25.6 15.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAN32183.1 - 5.1e-05 23.0 15.4 8.7e-05 22.3 15.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EAN32183.1 - 8.1e-05 22.4 11.0 0.00018 21.3 11.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 EAN32183.1 - 0.00053 20.3 15.0 0.00094 19.5 15.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EAN32183.1 - 0.019 14.9 15.9 0.041 13.8 15.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain APG12 PF04110.13 EAN32183.1 - 0.026 14.9 0.2 0.058 13.8 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 RE_Bpu10I PF09549.10 EAN32183.1 - 0.055 13.0 0.0 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 Bpu10I restriction endonuclease zf-rbx1 PF12678.7 EAN32183.1 - 0.31 11.4 8.8 0.8 10.0 8.8 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 EAN32183.1 - 0.31 10.9 8.6 0.21 11.5 6.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN32183.1 - 1.1 9.4 14.2 2.3 8.3 14.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 EAN32183.1 - 4.9 7.0 12.0 10 6.0 12.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SOGA PF11365.8 EAN32184.1 - 0.08 14.1 0.6 6 8.1 0.1 2.4 2 1 0 2 2 2 0 Protein SOGA TSC22 PF01166.18 EAN32184.1 - 0.15 12.4 1.5 0.44 10.9 0.9 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family SSP160 PF06933.11 EAN32184.1 - 0.16 10.1 7.7 0.19 9.9 7.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FtsJ PF01728.19 EAN32185.1 - 5.6e-57 192.7 0.4 1.4e-56 191.4 0.1 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Spb1_C PF07780.12 EAN32185.1 - 1.6e-40 139.1 16.5 1.6e-40 139.1 16.5 2.9 3 1 1 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.8 EAN32185.1 - 5.4e-35 120.6 8.1 5.4e-35 120.6 8.1 4.7 3 2 2 5 5 5 1 Domain of unknown function (DUF3381) ATP-synt_C PF00137.21 EAN32186.1 - 5.2e-28 97.2 25.8 2.3e-14 53.5 9.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C LANC_like PF05147.13 EAN32186.1 - 0.056 12.0 0.0 0.073 11.6 0.0 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein ING PF12998.7 EAN32187.1 - 0.0066 17.0 2.1 0.33 11.6 0.1 2.1 1 1 1 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding Spectrin_like PF18373.1 EAN32187.1 - 0.043 13.9 1.2 0.094 12.8 1.0 1.6 1 1 0 1 1 1 0 Spectrin like domain DNA_Packaging_2 PF11123.8 EAN32187.1 - 0.12 12.6 0.3 0.23 11.7 0.2 1.5 1 1 0 1 1 1 0 DNA packaging protein CtsR_C PF17727.1 EAN32188.1 - 0.012 15.7 2.6 0.024 14.8 0.1 2.7 3 0 0 3 3 3 0 CtsR C-terminal dimerization domain Acetyltransf_13 PF13880.6 EAN32188.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase KH_1 PF00013.29 EAN32189.1 - 0.14 12.0 0.1 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 KH domain Pentapeptide_4 PF13599.6 EAN32189.1 - 0.81 9.9 8.4 0.83 9.9 0.6 3.6 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) Excalibur PF05901.11 EAN32189.1 - 2.5 8.8 0.0 2.5 8.8 0.0 3.4 4 0 0 4 4 4 0 Excalibur calcium-binding domain S10_plectin PF03501.15 EAN32190.1 - 3.8e-41 139.1 0.2 4.5e-41 138.8 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Methyltransf_10 PF05971.12 EAN32191.1 - 1.3e-46 159.3 0.5 1.8e-38 132.6 0.0 4.4 3 1 0 3 3 3 3 RNA methyltransferase PrmA PF06325.13 EAN32191.1 - 1.8e-06 27.6 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EAN32191.1 - 5.7e-06 26.0 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EAN32191.1 - 0.0037 17.2 0.0 0.0078 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAN32191.1 - 0.08 13.7 0.0 0.23 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 EAN32191.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RRM_1 PF00076.22 EAN32192.1 - 6.1e-20 70.8 2.6 1.4e-19 69.6 0.0 2.9 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAN32192.1 - 0.0057 16.7 0.1 0.29 11.3 0.0 3.0 2 2 0 2 2 2 1 RNA recognition motif Mod_r PF07200.13 EAN32194.1 - 0.059 13.5 6.8 0.094 12.8 6.8 1.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CC2-LZ PF16516.5 EAN32194.1 - 0.1 13.0 5.4 0.21 12.0 5.4 1.6 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Phage_GPO PF05929.11 EAN32194.1 - 0.19 11.3 2.4 0.23 11.1 2.4 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DivIVA PF05103.13 EAN32195.1 - 0.0008 19.5 4.1 0.00091 19.3 4.1 1.2 1 0 0 1 1 1 1 DivIVA protein TMPIT PF07851.13 EAN32195.1 - 2.2 7.4 5.3 2.3 7.4 5.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein RsfS PF02410.15 EAN32197.1 - 4.5e-15 55.9 0.1 1e-14 54.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Ribosomal_S7e PF01251.18 EAN32198.1 - 8.8e-65 217.9 6.9 1e-64 217.7 6.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Glyco_transf_7N PF13733.6 EAN32198.1 - 0.088 12.4 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 SBF2 PF12335.8 EAN32199.1 - 8e-06 25.6 0.2 3.1e-05 23.7 0.3 1.9 2 0 0 2 2 2 1 Myotubularin protein FCH PF00611.23 EAN32199.1 - 8.3e-06 26.0 1.5 7.3e-05 23.0 0.5 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain FAM47 PF14642.6 EAN32199.1 - 0.0094 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 FAM47 family Baculo_PEP_C PF04513.12 EAN32199.1 - 0.025 14.6 1.8 0.29 11.2 0.3 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3666 PF12408.8 EAN32199.1 - 0.034 13.4 0.5 0.11 11.7 0.5 1.9 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Phage_HK97_TLTM PF06120.11 EAN32199.1 - 0.56 9.3 3.4 0.22 10.7 0.6 1.7 2 0 0 2 2 2 0 Tail length tape measure protein Lge1 PF11488.8 EAN32199.1 - 1.4 9.2 5.2 3 8.1 0.1 3.0 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 DnaJ PF00226.31 EAN32200.1 - 1.9e-06 27.9 0.1 5.6e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain HMG_box_2 PF09011.10 EAN32200.1 - 0.028 15.0 4.0 0.067 13.8 4.0 1.6 1 0 0 1 1 1 0 HMG-box domain RHD_DNA_bind PF00554.22 EAN32200.1 - 0.07 13.1 1.4 0.45 10.5 0.0 2.5 3 0 0 3 3 3 0 Rel homology DNA-binding domain LST1 PF05083.13 EAN32200.1 - 0.3 11.4 1.3 0.72 10.2 1.3 1.6 1 0 0 1 1 1 0 LST-1 protein V_ATPase_I PF01496.19 EAN32200.1 - 1.6 6.6 4.8 1.8 6.4 4.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L21p PF00829.21 EAN32201.1 - 1.2e-17 64.0 0.2 1.2e-17 64.0 0.2 1.6 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein DUF4265 PF14085.6 EAN32201.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) LA-virus_coat PF09220.10 EAN32201.1 - 0.14 10.8 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 L-A virus, major coat protein RIO1 PF01163.22 EAN32202.1 - 9.9e-43 145.9 0.9 9.9e-43 145.9 0.9 2.0 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 EAN32202.1 - 4.1e-31 107.0 0.1 1.4e-30 105.3 0.1 2.0 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EAN32202.1 - 5.7e-09 36.3 0.6 2.1e-05 24.6 0.6 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EAN32202.1 - 0.0001 21.8 0.1 0.11 11.9 0.1 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EAN32202.1 - 0.026 13.9 0.7 0.099 12.0 0.7 1.9 1 1 0 1 1 1 0 Protein kinase domain DUF2457 PF10446.9 EAN32202.1 - 1.1 8.3 22.2 1.5 7.9 22.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 EAN32202.1 - 6.6 4.9 16.2 11 4.2 16.2 1.2 1 0 0 1 1 1 0 CDC45-like protein PNRC PF15365.6 EAN32203.1 - 0.008 16.0 2.4 0.008 16.0 2.4 2.2 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif Dicty_REP PF05086.12 EAN32203.1 - 0.11 10.4 9.2 0.19 9.7 9.2 1.3 1 1 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UPF0160 PF03690.13 EAN32204.1 - 1.1e-93 314.3 1.5 1.4e-93 314.1 1.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Rad1 PF02144.16 EAN32205.1 - 0.00019 20.6 0.1 0.0006 19.0 0.1 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Peptidase_M22 PF00814.25 EAN32206.1 - 5.3e-43 147.7 0.0 9.3e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Glycoprotease family Ribosomal_S10 PF00338.22 EAN32208.1 - 2.3e-20 72.6 0.0 4.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ABC_tran PF00005.27 EAN32209.1 - 7.2e-35 120.5 0.0 4.9e-17 62.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 EAN32209.1 - 1e-12 47.7 5.5 2.5e-12 46.4 5.5 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 EAN32209.1 - 3.4e-10 40.2 10.6 0.012 15.5 0.0 4.3 2 2 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 EAN32209.1 - 1.1e-07 31.3 2.6 1.1e-07 31.3 2.6 2.3 3 0 0 3 3 2 1 4Fe-4S binding domain SMC_N PF02463.19 EAN32209.1 - 1.2e-07 31.5 3.8 0.082 12.3 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EAN32209.1 - 4e-06 27.3 0.0 0.017 15.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EAN32209.1 - 5.2e-06 26.4 0.0 0.08 12.6 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain Fer4_21 PF14697.6 EAN32209.1 - 3.3e-05 23.9 13.0 6.4e-05 23.0 13.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_22 PF13401.6 EAN32209.1 - 3.9e-05 23.9 0.0 0.0067 16.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAN32209.1 - 4.2e-05 23.5 0.1 0.14 12.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Fer4_6 PF12837.7 EAN32209.1 - 5.6e-05 23.0 2.4 5.6e-05 23.0 2.4 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 EAN32209.1 - 6.3e-05 22.6 0.4 0.37 10.6 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 EAN32209.1 - 7.2e-05 22.8 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA PF00004.29 EAN32209.1 - 9.3e-05 22.9 0.0 0.051 14.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EAN32209.1 - 0.00029 21.4 1.3 0.029 14.9 0.3 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAN32209.1 - 0.00033 20.6 1.3 0.034 14.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 EAN32209.1 - 0.00034 21.0 0.3 0.35 11.3 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_24 PF13479.6 EAN32209.1 - 0.00051 19.8 0.4 0.079 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EAN32209.1 - 0.00067 20.2 0.0 2 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EAN32209.1 - 0.0011 19.0 0.0 0.043 13.8 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EAN32209.1 - 0.0015 18.2 1.7 0.097 12.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_7 PF12838.7 EAN32209.1 - 0.0015 19.1 1.1 0.0015 19.1 1.1 2.7 2 1 2 4 4 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EAN32209.1 - 0.0044 17.0 0.8 0.0044 17.0 0.8 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain NB-ARC PF00931.22 EAN32209.1 - 0.0047 16.1 0.0 0.93 8.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Fer4_9 PF13187.6 EAN32209.1 - 0.0053 16.9 13.2 0.012 15.8 13.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_33 PF13671.6 EAN32209.1 - 0.0064 16.7 0.1 1.1 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 EAN32209.1 - 0.0071 16.4 1.4 0.0071 16.4 1.4 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_7 PF12775.7 EAN32209.1 - 0.0096 15.5 0.3 0.2 11.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region VirE PF05272.11 EAN32209.1 - 0.01 15.6 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_5 PF07728.14 EAN32209.1 - 0.013 15.5 0.5 0.58 10.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EAN32209.1 - 0.015 15.5 0.0 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EAN32209.1 - 0.017 14.9 0.1 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 EAN32209.1 - 0.018 14.7 1.0 5.5 6.6 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase AAA_28 PF13521.6 EAN32209.1 - 0.022 15.0 0.1 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EAN32209.1 - 0.022 14.7 1.0 0.97 9.3 0.0 2.6 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.23 EAN32209.1 - 0.041 14.0 0.8 8.6 6.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fer4_16 PF13484.6 EAN32209.1 - 0.044 14.7 0.9 0.044 14.7 0.9 2.7 2 1 1 3 3 2 0 4Fe-4S double cluster binding domain AAA_14 PF13173.6 EAN32209.1 - 0.085 12.9 0.0 5.5 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EAN32209.1 - 0.095 11.8 0.0 3.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.18 EAN32209.1 - 0.13 11.6 0.0 2 7.6 0.0 2.5 2 0 0 2 2 2 0 Septin Fer4_8 PF13183.6 EAN32209.1 - 0.16 12.5 0.2 0.16 12.5 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Roc PF08477.13 EAN32209.1 - 0.17 12.1 0.6 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Nucleotid_trans PF03407.16 EAN32209.1 - 0.2 11.6 0.0 5.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase Zeta_toxin PF06414.12 EAN32209.1 - 0.43 9.8 1.1 7.8 5.7 0.0 3.0 4 0 0 4 4 4 0 Zeta toxin Fer4_4 PF12800.7 EAN32209.1 - 0.98 10.1 14.7 0.28 11.8 2.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain PduV-EutP PF10662.9 EAN32209.1 - 1.5 8.6 3.3 2.9 7.6 0.1 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RRP36 PF06102.12 EAN32210.1 - 1.2e-28 100.1 24.3 1.2e-28 100.1 24.3 1.6 1 1 0 1 1 1 1 rRNA biogenesis protein RRP36 CPSase_L_D3 PF02787.19 EAN32210.1 - 1.4 9.3 7.7 17 5.8 7.6 2.3 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain RAP PF08373.10 EAN32212.1 - 3.9e-23 81.3 0.0 2.5e-22 78.7 0.0 2.2 2 0 0 2 2 2 1 RAP domain MTES_1575 PF18741.1 EAN32212.1 - 0.002 18.3 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 REase_MTES_1575 MMtag PF10159.9 EAN32212.1 - 0.033 14.5 2.0 0.17 12.2 0.1 2.2 2 0 0 2 2 2 0 Multiple myeloma tumor-associated Fer4_24 PF18109.1 EAN32213.1 - 0.01 16.1 0.0 0.033 14.5 0.0 1.9 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain FlaC_arch PF05377.11 EAN32213.1 - 4.9 7.6 9.7 6.9 7.1 4.8 3.0 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) SRP68 PF16969.5 EAN32214.1 - 7.2e-27 94.6 1.4 1e-26 94.1 1.4 1.2 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_2 PF07719.17 EAN32214.1 - 0.094 12.9 0.5 0.55 10.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Chordopox_A30L PF06015.12 EAN32215.1 - 0.008 16.0 0.4 0.015 15.1 0.1 1.6 1 1 1 2 2 2 1 Chordopoxvirus A30L protein MgrB PF13998.6 EAN32215.1 - 0.049 13.5 0.1 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 MgrB protein NAC PF01849.18 EAN32216.1 - 4.2e-20 71.5 0.2 7.6e-20 70.6 0.2 1.4 1 0 0 1 1 1 1 NAC domain Nrf1_DNA-bind PF10491.9 EAN32216.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Methyltrans_RNA PF04452.14 EAN32219.1 - 3.2e-40 137.9 0.0 4e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase FAST_1 PF06743.15 EAN32220.1 - 1.6e-09 37.6 7.1 0.0021 18.0 0.2 6.9 5 1 2 7 7 7 4 FAST kinase-like protein, subdomain 1 DUF3656 PF12392.8 EAN32220.1 - 0.14 12.8 0.5 1 10.0 0.1 2.5 2 0 0 2 2 2 0 Collagenase HEAT PF02985.22 EAN32222.1 - 0.00016 21.6 9.4 0.11 12.8 0.1 6.1 6 0 0 6 6 6 2 HEAT repeat MetJ PF01340.20 EAN32222.1 - 0.0083 16.1 0.1 0.11 12.5 0.1 2.6 2 0 0 2 2 2 1 Met Apo-repressor, MetJ TAF6_C PF07571.13 EAN32222.1 - 0.0096 16.2 3.2 4.3 7.7 0.0 5.6 6 1 0 6 6 6 1 TAF6 C-terminal HEAT repeat domain HEAT_2 PF13646.6 EAN32222.1 - 0.032 14.6 0.7 11 6.5 0.0 3.9 4 0 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 EAN32222.1 - 0.36 11.4 2.6 13 6.4 0.0 4.6 5 1 0 5 5 5 0 HEAT-like repeat C1_1 PF00130.22 EAN32223.1 - 0.0017 18.2 5.3 0.0017 18.2 5.3 1.9 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 EAN32223.1 - 0.066 12.8 5.5 0.12 12.0 5.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 EAN32223.1 - 1 9.5 6.4 0.22 11.6 0.6 1.6 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 EAN32223.1 - 1.1 9.7 11.1 0.072 13.4 5.7 1.9 2 0 0 2 2 2 0 C1 domain PHD PF00628.29 EAN32223.1 - 1.3 9.0 8.6 3.3 7.7 8.6 1.8 1 1 0 1 1 1 0 PHD-finger HEPN_Swt1 PF18731.1 EAN32224.1 - 7.5e-05 23.1 0.1 0.00021 21.6 0.0 1.8 2 0 0 2 2 2 1 Swt1-like HEPN tRNA_synthFbeta PF17759.1 EAN32225.1 - 1.2e-30 106.6 0.0 1.7e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 EAN32225.1 - 2.6e-22 79.3 0.0 4.1e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain PhetRS_B1 PF18262.1 EAN32225.1 - 4.7e-19 68.4 0.8 9.5e-17 61.0 0.4 2.8 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 EAN32225.1 - 1.1e-14 54.4 0.2 9e-12 45.1 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 EAN32225.1 - 0.012 15.2 0.0 0.049 13.1 0.0 1.9 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) AP2 PF00847.20 EAN32226.1 - 5.7e-13 48.9 0.6 9.9e-13 48.1 0.6 1.4 1 0 0 1 1 1 1 AP2 domain Como_SCP PF02248.16 EAN32226.1 - 0.057 13.0 1.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Small coat protein Wzz PF02706.15 EAN32226.1 - 0.15 12.4 1.3 2.1 8.7 0.0 2.9 3 0 0 3 3 3 0 Chain length determinant protein PPTA PF01239.22 EAN32227.1 - 1.5e-10 40.5 9.1 1.6e-05 24.5 0.2 4.5 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat LRR_4 PF12799.7 EAN32227.1 - 7.2e-06 26.3 2.4 7.2e-06 26.3 2.4 4.1 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAN32227.1 - 0.0026 17.5 10.4 0.0026 17.5 10.4 3.4 3 1 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 EAN32227.1 - 0.0073 16.3 6.6 4.5 7.6 0.4 4.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 EAN32227.1 - 0.52 11.1 13.7 1.7 9.5 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat Methyltransf_14 PF08484.11 EAN32228.1 - 0.13 12.1 0.1 0.19 11.5 0.0 1.3 1 1 0 1 1 1 0 C-methyltransferase C-terminal domain Sec7 PF01369.20 EAN32229.1 - 4.2e-61 205.8 8.0 4.2e-61 205.8 8.0 2.7 2 1 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 EAN32229.1 - 3.5e-18 66.0 10.2 3.5e-18 66.0 10.2 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DotA PF11388.8 EAN32229.1 - 1.2 9.4 5.8 0.35 11.1 1.4 2.3 2 0 0 2 2 2 0 Phagosome trafficking protein DotA EF_TS PF00889.19 EAN32231.1 - 0.00054 19.6 0.0 0.0014 18.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor TS Peptidase_C48 PF02902.19 EAN32232.1 - 8.1e-29 101.0 2.3 3.5e-28 98.9 1.3 2.3 1 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain PMI_typeI PF01238.21 EAN32233.1 - 2.4e-50 171.8 0.0 1.1e-48 166.3 0.0 2.5 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 EAN32233.1 - 0.0053 16.7 0.0 0.041 13.8 0.0 2.1 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 EAN32233.1 - 0.13 12.0 0.0 0.45 10.3 0.0 1.8 2 0 0 2 2 2 0 Cupin domain JmjC PF02373.22 EAN32233.1 - 0.16 12.4 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase Pkinase PF00069.25 EAN32234.1 - 7.2e-42 143.6 0.0 7e-36 123.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32234.1 - 3.2e-12 46.3 0.0 5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Gpi1 PF05024.15 EAN32235.1 - 2.8e-27 96.0 10.7 2.8e-27 96.0 10.7 2.2 1 1 1 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Amidohydro_2 PF04909.14 EAN32236.1 - 3e-06 27.2 0.0 4.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase DUF4187 PF13821.6 EAN32236.1 - 0.016 15.0 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) ELFV_dehydrog PF00208.21 EAN32237.1 - 5e-44 150.8 0.0 1.2e-43 149.7 0.0 1.7 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EAN32237.1 - 5.1e-18 64.1 0.0 6.9e-12 43.8 0.0 2.5 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase OAD_gamma PF04277.13 EAN32239.1 - 0.064 13.9 0.1 0.22 12.2 0.1 1.9 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Holin_SPP1 PF04688.13 EAN32239.1 - 0.84 9.8 0.1 0.84 9.8 0.1 2.9 3 0 0 3 3 3 0 SPP1 phage holin DUF4131 PF13567.6 EAN32239.1 - 9.6 5.8 7.2 4.9 6.8 1.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) SNF2_N PF00176.23 EAN32240.1 - 1.6e-26 92.9 0.3 1.6e-26 92.9 0.3 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAN32240.1 - 6.4e-09 36.1 0.1 5.9e-08 33.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN32240.1 - 1.8e-06 28.1 0.1 5.5e-05 23.2 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAN32240.1 - 0.0025 17.6 0.0 0.015 15.1 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase TK PF00265.18 EAN32240.1 - 0.0036 17.2 0.0 0.014 15.3 0.0 2.0 1 0 0 1 1 1 1 Thymidine kinase ERCC3_RAD25_C PF16203.5 EAN32240.1 - 0.07 12.3 0.1 0.07 12.3 0.1 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase FAINT PF04385.15 EAN32241.1 - 0.0037 17.3 0.2 0.0095 16.0 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function, DUF529 SF3A3 PF16837.5 EAN32243.1 - 3.1 8.4 8.8 0.81 10.2 0.6 2.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 S1 PF00575.23 EAN32244.1 - 1.4e-14 54.2 0.1 6e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 S1 RNA binding domain Fasciclin PF02469.22 EAN32245.1 - 1.5e-13 51.1 0.0 1.9e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain Ribosomal_L7Ae PF01248.26 EAN32246.1 - 1e-26 92.5 0.0 1.4e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EAN32246.1 - 0.00023 21.0 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 EAN32246.1 - 0.0013 18.8 0.0 0.0014 18.7 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Adenosine_kin PF04008.14 EAN32246.1 - 0.0023 17.7 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine specific kinase T3SSipB PF16535.5 EAN32246.1 - 0.0043 17.6 0.3 0.0056 17.2 0.3 1.2 1 0 0 1 1 1 1 Type III cell invasion protein SipB S-AdoMet_synt_C PF02773.16 EAN32247.1 - 1e-58 197.2 0.0 2e-58 196.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EAN32247.1 - 2.8e-43 147.0 0.0 5.7e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EAN32247.1 - 3e-38 130.5 0.5 6.7e-38 129.4 0.5 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidase PF01425.21 EAN32248.1 - 1.6e-61 208.7 0.1 3.1e-61 207.7 0.1 1.4 1 1 0 1 1 1 1 Amidase DeoC PF01791.9 EAN32248.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase RecG_N PF17190.4 EAN32248.1 - 1.2 9.9 5.8 0.27 12.0 1.2 2.3 2 0 0 2 2 2 0 RecG N-terminal helical domain zf-C3HC4_2 PF13923.6 EAN32249.1 - 7.2e-13 48.1 7.7 1.2e-12 47.4 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAN32249.1 - 1.8e-12 46.9 7.3 3.1e-12 46.1 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAN32249.1 - 1.2e-11 44.3 5.5 2.4e-11 43.3 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN32249.1 - 2.2e-10 40.4 2.4 2.2e-10 40.4 2.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAN32249.1 - 2.2e-10 40.3 6.8 4.2e-10 39.4 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EAN32249.1 - 1.9e-09 37.7 9.9 3.2e-09 37.0 9.9 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EAN32249.1 - 1.3e-08 34.6 6.2 2.3e-08 33.7 6.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EAN32249.1 - 3.8e-07 30.1 8.3 6.9e-07 29.3 8.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EAN32249.1 - 9.6e-05 22.6 7.5 0.00021 21.5 7.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Rtf2 PF04641.12 EAN32249.1 - 0.0024 17.3 0.6 0.0033 16.8 0.6 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-ANAPC11 PF12861.7 EAN32249.1 - 0.047 13.8 2.5 0.092 12.8 2.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EAN32249.1 - 0.079 12.6 4.7 0.14 11.8 4.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type U-box PF04564.15 EAN32249.1 - 0.094 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-RING_11 PF17123.5 EAN32249.1 - 0.11 12.3 9.3 0.13 12.1 4.5 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_6 PF14835.6 EAN32249.1 - 0.13 12.2 4.0 0.33 10.9 4.0 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EAN32249.1 - 0.31 10.9 7.4 1.2 9.0 7.4 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 EAN32249.1 - 3.3 8.0 8.7 11 6.3 8.8 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Elf1 PF05129.13 EAN32249.1 - 3.9 7.6 6.7 33 4.6 6.7 2.2 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF5331 PF17265.2 EAN32250.1 - 0.00033 20.3 2.8 0.99 9.2 0.1 3.4 2 1 1 3 3 3 2 Family of unknown function (DUF5331) OGFr_N PF04664.13 EAN32250.1 - 0.033 13.7 0.1 0.076 12.5 0.0 1.6 2 0 0 2 2 2 0 Opioid growth factor receptor (OGFr) conserved region Borrelia_orfD PF02999.14 EAN32250.1 - 0.056 13.8 10.5 4.5 7.6 0.1 5.2 5 1 1 6 6 6 0 Borrelia orf-D family DUF4313 PF14190.6 EAN32250.1 - 0.095 12.7 0.9 1.5 8.9 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4313) DUF1456 PF07308.13 EAN32250.1 - 0.099 13.0 3.9 12 6.3 0.1 4.6 3 2 1 4 4 4 0 Protein of unknown function (DUF1456) CHASE9 PF17153.4 EAN32250.1 - 0.18 12.0 11.4 12 6.1 0.0 5.1 5 2 1 6 6 6 0 Periplasmic sensor domain, extracellular DUF4363 PF14276.6 EAN32250.1 - 4.2 7.5 9.5 87 3.3 3.3 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4363) Patatin PF01734.22 EAN32251.1 - 0.0014 18.8 0.1 0.25 11.5 0.0 3.1 2 1 0 2 2 2 1 Patatin-like phospholipase AAA PF00004.29 EAN32252.1 - 5.2e-12 46.3 0.1 3.2e-11 43.8 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAN32252.1 - 0.002 18.5 0.0 0.0071 16.7 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EAN32252.1 - 0.0098 15.8 0.0 0.04 13.8 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 EAN32252.1 - 0.011 16.3 0.0 0.19 12.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EAN32252.1 - 0.074 13.1 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EAN32252.1 - 0.098 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EAN32252.1 - 0.099 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EAN32252.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EAN32252.1 - 0.14 12.4 0.1 0.77 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cnd1 PF12717.7 EAN32252.1 - 7.6 6.5 7.4 2 8.5 0.3 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CRAL_TRIO PF00650.20 EAN32253.1 - 9e-28 97.0 0.1 1.3e-27 96.5 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Yip1 PF04893.17 EAN32254.1 - 0.014 15.2 5.7 0.022 14.5 5.7 1.3 1 0 0 1 1 1 0 Yip1 domain Forkhead PF00250.18 EAN32255.1 - 0.08 13.2 0.3 1 9.6 0.1 2.9 2 0 0 2 2 2 0 Forkhead domain PBP_dimer PF03717.15 EAN32255.1 - 1.6 9.1 6.8 0.85 9.9 1.6 3.1 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain ANAPC4_WD40 PF12894.7 EAN32256.1 - 3.8e-06 27.1 0.2 0.02 15.2 0.0 3.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAN32256.1 - 0.00011 22.9 0.1 0.49 11.4 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat DsbC_N PF10411.9 EAN32256.1 - 0.074 12.5 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Na_trans_assoc PF06512.13 EAN32259.1 - 0.069 13.4 4.5 0.15 12.4 4.5 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated DUF5111 PF17138.4 EAN32259.1 - 0.13 12.2 0.1 7.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5111) Cwf_Cwc_15 PF04889.12 EAN32259.1 - 0.53 10.0 10.7 1.5 8.5 6.4 2.6 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Iwr1 PF08574.10 EAN32259.1 - 0.85 10.7 15.3 0.1 13.6 8.2 3.0 3 0 0 3 3 3 0 Transcription factor Iwr1 YL1 PF05764.13 EAN32259.1 - 7.1 6.7 7.9 13 5.8 7.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 EAN32259.1 - 9.8 5.4 8.2 17 4.6 8.2 1.3 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.22 EAN32260.1 - 2.5e-15 56.0 2.0 2.7e-10 39.9 0.1 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NRDE-2 PF08424.10 EAN32260.1 - 0.0031 16.7 2.7 0.65 9.1 0.0 3.4 2 2 2 4 4 4 2 NRDE-2, necessary for RNA interference Suf PF05843.14 EAN32260.1 - 0.007 16.4 0.1 3.1 7.7 0.0 2.6 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) GlutR_dimer PF00745.20 EAN32261.1 - 0.39 11.2 6.0 12 6.4 0.3 4.0 2 1 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain 7TMR-HDED PF07697.11 EAN32261.1 - 0.67 10.0 23.4 5.7 7.0 1.4 4.8 2 2 1 3 3 3 0 7TM-HD extracellular Arm PF00514.23 EAN32262.1 - 5.1e-83 270.9 8.2 3.3e-13 49.2 0.0 8.8 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EAN32262.1 - 2.8e-24 85.2 0.1 7.3e-08 32.8 0.1 5.3 4 2 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 EAN32262.1 - 1.1e-19 70.6 0.0 1.8e-07 31.4 0.1 5.2 1 1 3 5 5 5 4 HEAT repeats HEAT PF02985.22 EAN32262.1 - 7.4e-15 53.8 0.5 0.0022 18.1 0.0 7.2 7 0 0 7 7 7 3 HEAT repeat Arm_3 PF16186.5 EAN32262.1 - 9.9e-15 53.8 0.0 3.1e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 EAN32262.1 - 9.9e-11 41.9 1.8 3.3e-10 40.3 1.8 1.9 1 0 0 1 1 1 1 Importin beta binding domain RICTOR_V PF14668.6 EAN32262.1 - 9.2e-06 25.8 2.5 0.93 9.8 0.1 5.2 3 1 3 6 6 6 3 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 EAN32262.1 - 0.00011 21.8 0.0 1.5 8.2 0.0 4.2 1 1 0 3 3 3 2 Armadillo-like Adaptin_N PF01602.20 EAN32262.1 - 0.00049 18.8 0.1 0.058 11.9 0.0 2.9 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 EAN32262.1 - 0.00054 20.1 0.1 11 6.1 0.0 4.5 3 2 0 4 4 4 1 V-ATPase subunit H NopRA1 PF16201.5 EAN32262.1 - 0.00099 18.7 0.1 0.019 14.6 0.0 2.9 3 1 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 HEAT_PBS PF03130.16 EAN32262.1 - 0.0037 17.8 1.6 1.6 9.6 0.1 4.7 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 EAN32262.1 - 0.017 15.1 0.0 0.44 10.6 0.0 3.0 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Fe_dep_repr_C PF02742.15 EAN32262.1 - 0.056 13.5 0.0 14 5.9 0.0 3.7 4 0 0 4 4 4 0 Iron dependent repressor, metal binding and dimerisation domain NPL PF17800.1 EAN32263.1 - 1.9e-11 44.5 0.0 1.9e-11 44.5 0.0 1.5 2 0 0 2 2 2 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 EAN32263.1 - 0.0093 16.4 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain CDC45 PF02724.14 EAN32263.1 - 0.17 10.1 2.3 0.15 10.4 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 EAN32263.1 - 0.58 9.2 6.7 0.74 8.9 6.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 EAN32263.1 - 1.7 9.1 11.8 2.6 8.5 11.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EAN32263.1 - 3.9 6.7 7.2 4.2 6.6 7.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2040 PF09745.9 EAN32264.1 - 3.2e-13 49.8 19.0 2.1e-11 43.9 19.0 2.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) Ac110_PIF PF07280.11 EAN32264.1 - 0.054 13.3 0.4 0.13 12.1 0.4 1.6 1 0 0 1 1 1 0 Per os infectivity factor AC110 UPF0239 PF06783.11 EAN32264.1 - 0.23 11.7 0.1 0.23 11.7 0.1 3.2 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0239) RNA_pol_Rpb5_C PF01191.19 EAN32265.1 - 2.6e-33 113.7 0.3 5.1e-33 112.8 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EAN32265.1 - 1.9e-22 79.6 1.5 2.5e-22 79.2 0.7 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EAN32265.1 - 0.00043 20.3 0.0 0.0008 19.4 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Sof1 PF04158.14 EAN32265.1 - 0.014 15.6 0.2 0.014 15.6 0.2 2.3 2 1 0 2 2 2 0 Sof1-like domain YxiJ PF14176.6 EAN32265.1 - 0.066 13.7 2.0 0.21 12.1 0.2 2.3 2 1 0 2 2 2 0 YxiJ-like protein WD40 PF00400.32 EAN32266.1 - 3.7e-06 27.6 8.6 0.053 14.4 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat RPS31 PF17067.5 EAN32266.1 - 0.43 10.8 3.4 2.1 8.6 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein S31e Rieske PF00355.26 EAN32267.1 - 1.2e-12 47.6 0.0 2.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain ABC_tran PF00005.27 EAN32268.1 - 2e-30 106.1 0.0 3e-14 53.7 0.0 2.8 2 1 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EAN32268.1 - 5.4e-05 23.1 0.2 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_membrane PF00664.23 EAN32268.1 - 6.2e-05 22.8 20.7 6.2e-05 22.8 20.7 3.3 3 0 0 3 3 2 1 ABC transporter transmembrane region AAA_21 PF13304.6 EAN32268.1 - 0.00017 21.5 0.7 0.6 9.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAN32268.1 - 0.00038 20.1 0.5 0.36 10.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EAN32268.1 - 0.00052 20.3 1.9 0.31 11.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EAN32268.1 - 0.00082 19.9 0.0 0.65 10.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAN32268.1 - 0.002 18.5 0.0 2.7 8.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EAN32268.1 - 0.0021 18.6 4.4 0.44 11.0 0.4 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EAN32268.1 - 0.0043 17.4 0.2 0.25 11.7 0.0 3.3 3 0 0 3 3 2 1 RNA helicase AAA_30 PF13604.6 EAN32268.1 - 0.011 15.5 0.4 0.82 9.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 EAN32268.1 - 0.011 14.7 0.1 4.1 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain NB-ARC PF00931.22 EAN32268.1 - 0.027 13.7 0.9 0.48 9.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EAN32268.1 - 0.034 14.1 0.0 0.034 14.1 0.0 4.0 5 0 0 5 5 3 0 ATPase domain predominantly from Archaea AAA PF00004.29 EAN32268.1 - 0.036 14.5 0.2 1.4 9.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EAN32268.1 - 0.042 13.9 2.6 0.63 10.1 0.4 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 EAN32268.1 - 0.044 13.2 2.0 0.089 12.2 0.4 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 EAN32268.1 - 0.046 13.0 0.1 3.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 EAN32268.1 - 0.052 12.6 0.1 1.8 7.6 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.6 EAN32268.1 - 0.054 13.5 0.7 3.8 7.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EAN32268.1 - 0.074 13.0 0.4 4.6 7.1 0.1 2.4 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 EAN32268.1 - 0.074 13.0 0.6 13 5.6 0.1 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 EAN32268.1 - 0.079 12.5 0.9 1.7 8.2 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EAN32268.1 - 0.087 11.8 0.2 0.27 10.2 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 EAN32268.1 - 0.12 12.4 0.3 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EAN32268.1 - 0.17 11.5 0.1 6.6 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EAN32268.1 - 0.17 11.9 2.0 5.9 6.9 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AAA_19 PF13245.6 EAN32268.1 - 0.19 12.1 0.7 18 5.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EAN32268.1 - 0.19 11.5 0.1 0.55 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EAN32268.1 - 0.24 11.3 0.5 2.1 8.2 0.3 2.4 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 EAN32268.1 - 0.28 11.2 3.6 0.9 9.6 0.5 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain FAINT PF04385.15 EAN32270.1 - 0.0031 17.5 6.1 0.78 9.8 1.6 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Shisa PF13908.6 EAN32270.1 - 0.18 12.0 0.2 0.18 12.0 0.2 2.6 2 1 0 3 3 3 0 Wnt and FGF inhibitory regulator Tash_PEST PF07708.11 EAN32271.1 - 1.5e-08 34.5 3.8 8.5e-08 32.1 3.8 2.5 1 0 0 1 1 1 1 Tash protein PEST motif FAINT PF04385.15 EAN32271.1 - 4.7e-08 33.0 11.1 9.5e-08 32.0 3.6 2.8 2 1 0 2 2 2 1 Domain of unknown function, DUF529 DUF2118 PF09891.9 EAN32271.1 - 0.045 13.7 0.3 0.071 13.1 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Trypan_PARP PF05887.11 EAN32271.1 - 0.071 13.1 0.0 0.071 13.1 0.0 3.0 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) SUZ PF12752.7 EAN32271.1 - 0.59 10.9 10.1 1.5 9.6 0.7 3.2 2 1 0 2 2 2 0 SUZ domain DUF5643 PF18705.1 EAN32271.1 - 4.2 7.4 9.7 0.48 10.4 0.2 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5643) FAINT PF04385.15 EAN32272.1 - 1.2e-05 25.3 4.7 0.00027 21.0 0.0 3.0 2 2 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32273.1 - 1.1 9.3 9.1 0.087 12.9 0.6 3.3 3 1 0 3 3 3 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32274.1 - 2.9 8.0 21.5 1.1 9.4 7.6 3.3 3 1 0 3 3 3 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32275.1 - 0.0021 18.1 2.8 0.023 14.8 0.5 2.9 2 2 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32276.1 - 3.7e-10 39.7 4.5 3.7e-10 39.7 4.5 3.3 3 1 0 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32277.1 - 3.9e-06 26.8 2.8 3.9e-06 26.8 2.8 3.3 2 2 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32279.1 - 4.2e-138 449.7 183.4 4.7e-23 81.0 2.4 24.1 23 1 0 23 23 23 23 Domain of unknown function, DUF529 Rdx PF10262.9 EAN32279.1 - 0.049 13.8 0.0 8.7 6.6 0.0 3.9 3 0 0 3 3 3 0 Rdx family DUF1829 PF08862.10 EAN32279.1 - 0.56 10.7 13.0 0.55 10.8 0.1 4.8 5 0 0 5 5 5 0 Domain of unknown function DUF1829 FAINT PF04385.15 EAN32280.1 - 0.00048 20.1 0.4 0.00048 20.1 0.4 3.5 2 1 2 4 4 4 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32281.1 - 4.5e-06 26.6 2.8 3e-05 24.0 0.5 2.5 2 0 0 2 2 2 1 Domain of unknown function, DUF529 CDC45 PF02724.14 EAN32282.1 - 0.94 7.7 5.7 1.5 7.0 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein FAINT PF04385.15 EAN32284.1 - 2.7e-08 33.7 15.5 1.3e-06 28.3 2.3 2.8 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32285.1 - 0.0069 16.4 1.2 3.3 7.8 0.1 2.9 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32286.1 - 3.8e-07 30.1 14.4 1.2e-06 28.5 2.3 2.8 2 1 0 2 2 2 2 Domain of unknown function, DUF529 GbpC PF08363.10 EAN32286.1 - 0.022 14.2 0.8 0.23 10.9 0.0 2.2 1 1 0 2 2 2 0 Glucan-binding protein C FAINT PF04385.15 EAN32287.1 - 1.3e-25 89.2 37.8 4.4e-07 29.9 4.5 4.6 4 0 0 4 4 4 4 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32288.1 - 1.9e-36 123.9 64.7 5.5e-08 32.8 1.8 6.7 6 1 0 6 6 6 6 Domain of unknown function, DUF529 DUF4451 PF14616.6 EAN32288.1 - 0.022 14.9 0.8 3.5 7.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) ATF7IP_BD PF16788.5 EAN32288.1 - 7.7 6.5 7.2 15 5.6 7.2 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain FAINT PF04385.15 EAN32289.1 - 4.3e-15 55.5 10.6 2.7e-14 53.0 2.6 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Pep1_7 PF17232.2 EAN32289.1 - 0.061 13.8 0.2 0.14 12.6 0.2 1.5 1 0 0 1 1 1 0 Elicitor peptide 1-7 Mononeg_mRNAcap PF14318.6 EAN32290.1 - 0.25 10.6 1.1 0.44 9.8 1.1 1.3 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V FAINT PF04385.15 EAN32290.1 - 0.47 10.5 5.8 0.068 13.2 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32291.1 - 0.00015 21.8 5.5 0.0013 18.7 1.3 2.7 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32292.1 - 2.6e-05 24.2 5.8 0.082 13.0 0.8 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Mononeg_mRNAcap PF14318.6 EAN32292.1 - 0.25 10.6 1.1 0.45 9.7 1.1 1.3 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V FAINT PF04385.15 EAN32293.1 - 0.00065 19.7 3.7 0.014 15.4 0.5 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32294.1 - 1e-10 41.5 6.5 7.4e-05 22.7 0.7 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN32295.1 - 0.00011 22.2 8.8 0.0033 17.5 0.4 3.7 4 0 0 4 4 4 2 Tash protein PEST motif FAINT PF04385.15 EAN32296.1 - 0.001 19.1 0.3 0.001 19.1 0.3 3.1 3 1 0 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32297.1 - 1.1e-08 35.0 12.1 0.0001 22.3 4.7 3.5 2 1 0 2 2 2 2 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN32297.1 - 2.4e-07 30.7 8.3 6.2e-07 29.4 8.3 1.8 1 0 0 1 1 1 1 Tash protein PEST motif FAINT PF04385.15 EAN32298.1 - 9.6e-37 124.9 63.0 9.2e-10 38.5 3.1 7.5 7 0 0 7 7 7 7 Domain of unknown function, DUF529 B_lectin PF01453.24 EAN32298.1 - 0.13 12.8 1.8 89 3.7 0.0 4.5 5 0 0 5 5 5 0 D-mannose binding lectin FAINT PF04385.15 EAN32299.1 - 4.4e-13 49.1 11.8 1.7e-06 28.0 1.5 3.6 3 0 0 3 3 3 3 Domain of unknown function, DUF529 LYRIC PF15686.5 EAN32300.1 - 0.3 10.6 4.7 0.43 10.1 4.7 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family APOBEC3 PF18771.1 EAN32300.1 - 4.7 7.3 9.5 2.9 8.0 0.1 3.3 3 1 1 4 4 4 0 APOBEC3 ABC_tran PF00005.27 EAN32302.1 - 1e-30 107.0 0.0 8.8e-18 65.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.12 EAN32302.1 - 1e-06 28.2 0.1 0.04 13.2 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 EAN32302.1 - 2.2e-06 27.7 0.7 0.03 14.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 EAN32302.1 - 0.00045 19.3 0.0 0.06 12.3 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 EAN32302.1 - 0.00099 18.8 0.6 1.8 8.4 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EAN32302.1 - 0.0059 16.9 0.2 1.2 9.4 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_23 PF13476.6 EAN32302.1 - 0.0065 17.0 3.4 0.51 10.8 0.6 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EAN32302.1 - 0.0093 15.2 0.8 0.36 10.0 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain AAA_16 PF13191.6 EAN32302.1 - 0.0093 16.4 0.0 4 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 EAN32302.1 - 0.011 14.9 0.1 1.3 8.0 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EAN32302.1 - 0.012 15.6 0.1 3.4 7.5 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 EAN32302.1 - 0.014 15.4 0.7 0.22 11.6 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EAN32302.1 - 0.033 13.9 0.1 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EAN32302.1 - 0.034 14.1 0.1 9.1 6.2 0.0 3.2 3 0 0 3 3 3 0 NACHT domain TsaE PF02367.17 EAN32302.1 - 0.036 14.1 0.1 8.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EAN32302.1 - 0.067 12.7 0.4 1.7 8.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 EAN32302.1 - 0.074 12.5 0.0 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Rad17 PF03215.15 EAN32302.1 - 0.09 12.7 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain DUF815 PF05673.13 EAN32302.1 - 0.1 11.8 0.2 0.48 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) VraX PF17412.2 EAN32302.1 - 0.11 12.1 0.9 0.87 9.3 0.0 2.9 4 0 0 4 4 3 0 Family of unknown function AAA_18 PF13238.6 EAN32302.1 - 0.12 12.9 0.1 5 7.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EAN32302.1 - 0.16 11.7 2.8 1.2 8.9 0.3 2.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 EAN32302.1 - 0.23 11.4 1.0 23 4.8 0.1 2.5 2 0 0 2 2 2 0 NTPase MobB PF03205.14 EAN32302.1 - 0.23 11.3 1.7 1.8 8.5 0.2 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 EAN32302.1 - 0.24 11.4 0.3 5.3 7.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EAN32302.1 - 0.33 11.0 1.2 0.48 10.5 0.2 1.8 2 0 0 2 2 1 0 Helicase HerA, central domain ABC_tran PF00005.27 EAN32303.1 - 1.7e-30 106.3 0.0 3.4e-16 60.0 0.0 2.6 2 1 0 2 2 2 2 ABC transporter MeaB PF03308.16 EAN32303.1 - 3e-06 26.4 0.1 0.0017 17.4 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EAN32303.1 - 3.5e-06 26.4 0.1 0.048 12.9 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 EAN32303.1 - 5e-06 26.5 0.5 0.081 12.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EAN32303.1 - 4.5e-05 23.9 0.0 0.14 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EAN32303.1 - 0.00046 19.9 0.5 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ATPase_2 PF01637.18 EAN32303.1 - 0.0016 18.4 0.1 0.37 10.7 0.0 2.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 EAN32303.1 - 0.0031 17.6 0.5 0.16 12.1 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EAN32303.1 - 0.0055 17.0 0.5 1.1 9.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.6 EAN32303.1 - 0.0085 15.9 0.7 0.85 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EAN32303.1 - 0.011 16.3 0.2 5.7 7.5 0.1 2.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EAN32303.1 - 0.012 14.7 0.2 0.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 EAN32303.1 - 0.012 14.8 0.5 0.56 9.3 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 EAN32303.1 - 0.015 15.9 6.9 0.58 10.6 0.6 3.0 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 EAN32303.1 - 0.015 15.2 0.2 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EAN32303.1 - 0.017 14.9 0.3 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arch_flagellin PF01917.16 EAN32303.1 - 0.028 14.6 1.2 0.064 13.4 1.2 1.6 1 0 0 1 1 1 0 Archaebacterial flagellin RNA_helicase PF00910.22 EAN32303.1 - 0.036 14.4 0.2 9 6.7 0.0 3.3 3 0 0 3 3 2 0 RNA helicase KAP_NTPase PF07693.14 EAN32303.1 - 0.038 13.2 0.3 11 5.1 0.0 2.9 3 0 0 3 3 3 0 KAP family P-loop domain Viral_helicase1 PF01443.18 EAN32303.1 - 0.04 13.6 0.1 7.3 6.3 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EAN32303.1 - 0.075 13.0 0.3 20 5.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EAN32303.1 - 0.076 12.9 1.3 9.4 6.1 0.2 2.5 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.7 EAN32303.1 - 0.098 11.6 0.2 6.4 5.6 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.13 EAN32303.1 - 0.1 11.7 0.1 0.47 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.14 EAN32303.1 - 0.12 12.3 2.4 1.3 9.0 0.3 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EAN32303.1 - 0.13 11.9 1.8 2.6 7.6 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 EAN32303.1 - 0.13 11.2 1.8 1.9 7.3 0.5 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 EAN32303.1 - 0.14 11.9 0.1 13 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EAN32303.1 - 0.14 12.2 3.7 0.19 11.8 0.4 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_25 PF13481.6 EAN32303.1 - 0.16 11.5 0.0 11 5.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 EAN32303.1 - 0.35 10.9 2.4 8.8 6.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 EAN32303.1 - 0.77 10.0 2.7 16 5.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EAN32303.1 - 8.5 5.7 6.7 2.2 7.7 0.2 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain FAINT PF04385.15 EAN32304.1 - 1.2e-20 73.3 36.1 1.5e-08 34.5 4.2 3.8 3 1 0 3 3 3 3 Domain of unknown function, DUF529 TFIIA PF03153.13 EAN32304.1 - 0.014 15.4 13.0 0.019 15.0 13.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAINT PF04385.15 EAN32305.1 - 5.5e-57 189.8 93.3 3.2e-09 36.7 1.4 13.7 12 1 0 13 13 13 11 Domain of unknown function, DUF529 Telomere_reg-2 PF10193.9 EAN32306.1 - 0.0068 16.8 4.6 0.58 10.6 1.9 3.7 2 1 0 2 2 2 1 Telomere length regulation protein SNF5 PF04855.12 EAN32307.1 - 0.026 14.3 1.5 1.2 8.9 0.3 2.5 2 1 0 2 2 2 0 SNF5 / SMARCB1 / INI1 RPA_C PF08784.11 EAN32308.1 - 0.043 14.5 0.1 0.081 13.6 0.1 1.5 1 0 0 1 1 1 0 Replication protein A C terminal PH PF00169.29 EAN32309.1 - 0.0011 19.4 0.4 0.003 18.0 0.4 1.8 1 0 0 1 1 1 1 PH domain HECT PF00632.25 EAN32311.1 - 6.9e-94 314.8 1.0 1.3e-93 313.9 0.2 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF3944 PF13099.6 EAN32312.1 - 0.038 13.9 0.1 5.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) RsgA_GTPase PF03193.16 EAN32313.1 - 6.5e-06 26.2 0.5 1.5e-05 25.0 0.5 1.5 1 1 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EAN32313.1 - 2.3e-05 24.4 0.0 0.00014 21.9 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAN32313.1 - 0.0068 15.9 0.1 0.36 10.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Ras PF00071.22 EAN32313.1 - 0.022 14.3 0.0 0.9 9.1 0.0 2.2 2 0 0 2 2 2 0 Ras family Roc PF08477.13 EAN32313.1 - 0.034 14.4 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EAN32313.1 - 0.05 14.0 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EAN32313.1 - 0.055 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EAN32313.1 - 0.086 12.3 0.1 4.6 6.7 0.0 2.3 1 1 1 2 2 2 0 ADP-ribosylation factor family ArsR PF09824.9 EAN32314.1 - 0.045 13.4 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 ArsR transcriptional regulator TFIID-18kDa PF02269.16 EAN32315.1 - 0.081 13.0 0.1 1.9 8.6 0.0 3.2 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit FAINT PF04385.15 EAN32316.1 - 2.6e-07 30.6 8.0 2.6e-07 30.6 8.0 4.2 4 0 0 4 4 4 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32318.1 - 4.5e-09 36.2 39.0 1.1e-05 25.4 1.1 5.8 5 1 0 5 5 5 4 Domain of unknown function, DUF529 Phage_XkdX PF09693.10 EAN32318.1 - 0.064 13.3 1.9 3.9 7.6 0.1 3.0 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) BRCT_2 PF16589.5 EAN32319.1 - 0.00099 19.5 3.0 0.086 13.3 0.0 3.0 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain DUF3552 PF12072.8 EAN32319.1 - 0.067 12.6 0.4 0.11 11.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) NusB PF01029.18 EAN32319.1 - 0.13 12.5 0.3 0.45 10.8 0.2 2.0 2 0 0 2 2 2 0 NusB family V-ATPase_C PF03223.15 EAN32320.1 - 2.2e-83 280.7 7.1 2.6e-83 280.5 7.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Thioredoxin PF00085.20 EAN32321.1 - 2.9e-20 72.2 0.1 3.7e-20 71.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAN32321.1 - 0.00016 21.9 0.0 0.00029 21.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 EAN32321.1 - 0.0012 19.0 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin OST3_OST6 PF04756.13 EAN32321.1 - 0.0039 16.6 0.1 0.0047 16.3 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF953 PF06110.11 EAN32321.1 - 0.0067 16.0 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_3 PF13192.6 EAN32321.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.6 EAN32321.1 - 0.016 15.7 0.1 0.055 13.9 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.6 EAN32321.1 - 0.028 14.2 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EAN32321.1 - 0.061 13.5 0.2 0.091 13.0 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like Yippee-Mis18 PF03226.14 EAN32322.1 - 2.7e-14 53.2 0.0 6.9e-14 51.9 0.0 1.7 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_6 PF14599.6 EAN32322.1 - 0.00029 20.8 0.1 0.024 14.6 0.0 2.2 2 0 0 2 2 2 1 Zinc-ribbon Zn_ribbon_recom PF13408.6 EAN32322.1 - 0.022 15.3 0.1 7.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.6 EAN32322.1 - 0.044 14.2 0.0 0.45 10.9 0.0 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF2321 PF10083.9 EAN32322.1 - 0.059 13.0 0.0 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) MBA1 PF07961.11 EAN32323.1 - 0.042 12.9 0.2 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 MBA1-like protein DUF1871 PF08958.10 EAN32323.1 - 0.073 13.4 1.5 27 5.2 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1871) DUF445 PF04286.12 EAN32323.1 - 0.68 9.7 4.2 17 5.0 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF445) FAST_1 PF06743.15 EAN32323.1 - 3.1 7.8 6.7 6.3 6.8 0.3 3.8 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 FAINT PF04385.15 EAN32324.1 - 6.5e-06 26.1 7.2 6.4e-05 22.9 2.2 3.0 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Biotin_lipoyl PF00364.22 EAN32324.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme Hist_deacetyl PF00850.19 EAN32325.1 - 5.9e-80 269.0 1.0 6e-80 269.0 0.2 1.4 2 0 0 2 2 2 1 Histone deacetylase domain tRNA-synt_2b PF00587.25 EAN32326.1 - 1.9e-21 76.8 0.1 2.9e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EAN32326.1 - 1.9e-05 24.7 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Metallophos PF00149.28 EAN32328.1 - 5.9e-37 128.2 0.3 9.5e-37 127.5 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SLBP_RNA_bind PF15247.6 EAN32328.1 - 5.6e-06 26.4 0.5 1.3e-05 25.2 0.5 1.6 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain STPPase_N PF16891.5 EAN32328.1 - 8.4e-05 22.9 0.2 0.00025 21.4 0.2 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EAN32328.1 - 0.22 11.7 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain MBA1 PF07961.11 EAN32329.1 - 0.043 12.9 0.2 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 MBA1-like protein DUF1871 PF08958.10 EAN32329.1 - 0.073 13.4 1.5 28 5.2 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1871) DUF445 PF04286.12 EAN32329.1 - 1.4 8.6 5.3 31 4.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF445) FAST_1 PF06743.15 EAN32329.1 - 3.7 7.6 6.7 6.3 6.8 0.3 3.7 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 Histone PF00125.24 EAN32330.1 - 1.1e-19 71.1 0.5 1.1e-19 71.1 0.5 2.8 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EAN32330.1 - 0.12 12.6 0.1 0.4 10.9 0.1 1.9 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Dicty_REP PF05086.12 EAN32330.1 - 4 5.3 8.7 20 3.0 0.0 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein COX5B PF01215.19 EAN32331.1 - 2.3e-12 46.7 0.0 8.3e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Vb Aminotran_1_2 PF00155.21 EAN32332.1 - 9e-44 150.1 0.0 1.1e-43 149.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_TL5_C PF14693.6 EAN32333.1 - 0.0023 18.2 0.0 0.0047 17.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Pro_isomerase PF00160.21 EAN32334.1 - 5.4e-44 150.2 0.1 6.6e-44 150.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAINT PF04385.15 EAN32335.1 - 1.3e-16 60.4 25.3 2.7e-09 37.0 1.9 5.4 5 1 0 5 5 5 4 Domain of unknown function, DUF529 NTF2 PF02136.20 EAN32336.1 - 9.4e-28 97.2 0.1 1.1e-27 97.0 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain GATase PF00117.28 EAN32338.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I ABC2_membrane_3 PF12698.7 EAN32338.1 - 0.23 10.6 4.5 8.9 5.3 2.6 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein FAINT PF04385.15 EAN32339.1 - 5.9e-14 51.9 42.2 1.7e-11 44.0 2.1 6.8 5 2 1 6 6 6 4 Domain of unknown function, DUF529 DNA_gyraseA_C PF03989.13 EAN32339.1 - 0.035 13.6 1.3 0.67 9.5 0.0 2.7 3 0 0 3 3 3 0 DNA gyrase C-terminal domain, beta-propeller PIP5K PF01504.18 EAN32340.1 - 6.5e-37 127.2 2.1 8.5e-26 90.8 0.8 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Rtt106 PF08512.12 EAN32341.1 - 0.24 11.9 3.7 1.4 9.4 0.1 3.2 3 0 0 3 3 3 0 Histone chaperone Rttp106-like Actin PF00022.19 EAN32342.1 - 1.9e-105 352.8 0.0 1.9e-103 346.2 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EAN32342.1 - 9.9e-05 21.3 0.0 0.025 13.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein NMT PF01233.19 EAN32343.1 - 4.1e-71 238.0 0.0 6.6e-71 237.3 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 EAN32343.1 - 7.7e-58 195.5 2.2 1.1e-57 194.9 1.8 1.4 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 EAN32343.1 - 0.0013 19.0 0.0 0.004 17.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EAN32343.1 - 0.0042 17.2 0.0 0.019 15.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DS PF01916.17 EAN32344.1 - 4.6e-127 423.2 0.0 5.5e-127 422.9 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase AAA PF00004.29 EAN32345.1 - 1.6e-77 258.3 0.0 9.3e-42 142.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAN32345.1 - 4.8e-11 43.3 0.0 9.1e-05 22.9 0.0 4.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 EAN32345.1 - 9.3e-11 41.4 0.0 1e-07 31.6 0.0 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EAN32345.1 - 3.1e-10 40.2 0.0 1.9e-05 24.7 0.0 3.8 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAN32345.1 - 7.9e-10 39.1 0.6 1.4e-06 28.6 0.0 4.0 3 1 1 4 4 4 1 AAA domain AAA_2 PF07724.14 EAN32345.1 - 2e-08 34.5 0.0 0.0013 18.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EAN32345.1 - 2.8e-08 33.7 0.0 0.0048 16.7 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EAN32345.1 - 1.2e-07 32.1 0.0 0.011 16.1 0.0 3.7 3 1 1 4 4 3 2 RNA helicase AAA_14 PF13173.6 EAN32345.1 - 1.6e-07 31.4 0.0 0.0018 18.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.15 EAN32345.1 - 6.2e-07 29.5 1.9 0.0018 18.2 0.2 2.8 3 0 0 3 3 2 2 Rad17 P-loop domain Mg_chelatase PF01078.21 EAN32345.1 - 1e-06 28.3 0.0 0.0077 15.6 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EAN32345.1 - 1.2e-06 28.7 0.5 0.00015 21.8 0.4 3.0 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EAN32345.1 - 3.8e-06 26.5 0.0 0.032 13.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 EAN32345.1 - 1.1e-05 24.9 0.5 0.11 11.8 0.0 3.4 3 0 0 3 3 3 1 KaiC IstB_IS21 PF01695.17 EAN32345.1 - 6.4e-05 22.8 0.0 0.24 11.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 EAN32345.1 - 0.00012 21.4 0.2 0.21 10.7 0.0 3.6 3 1 1 4 4 3 1 TIP49 P-loop domain AAA_33 PF13671.6 EAN32345.1 - 0.00015 22.0 0.0 0.34 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 EAN32345.1 - 0.00015 21.8 0.0 0.084 13.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 EAN32345.1 - 0.00026 20.8 0.1 0.012 15.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 EAN32345.1 - 0.00033 20.6 0.1 0.025 14.5 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_18 PF13238.6 EAN32345.1 - 0.0006 20.4 0.4 0.12 13.0 0.0 3.5 4 0 0 4 4 3 1 AAA domain TsaE PF02367.17 EAN32345.1 - 0.00079 19.4 0.0 1.6 8.7 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 EAN32345.1 - 0.00089 18.4 0.0 0.25 10.4 0.0 2.5 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 EAN32345.1 - 0.00096 19.7 0.0 0.49 10.9 0.0 2.7 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 EAN32345.1 - 0.0012 18.6 0.0 0.63 9.7 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain NB-ARC PF00931.22 EAN32345.1 - 0.0013 17.9 0.0 0.25 10.5 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain Vps4_C PF09336.10 EAN32345.1 - 0.004 17.1 0.0 11 6.2 0.0 3.5 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 EAN32345.1 - 0.0074 15.9 0.1 0.57 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EAN32345.1 - 0.013 14.8 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SRPRB PF09439.10 EAN32345.1 - 0.014 14.9 0.0 0.23 10.9 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_17 PF13207.6 EAN32345.1 - 0.016 15.6 0.1 0.74 10.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 EAN32345.1 - 0.025 13.7 0.0 37 3.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 EAN32345.1 - 0.028 14.2 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EAN32345.1 - 0.038 13.8 0.0 13 5.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EAN32345.1 - 0.046 14.0 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ACDC PF14733.6 EAN32345.1 - 0.065 13.5 0.5 0.56 10.6 0.1 2.6 2 0 0 2 2 2 0 AP2-coincident C-terminal Viral_helicase1 PF01443.18 EAN32345.1 - 0.13 12.0 0.1 3.4 7.4 0.1 2.7 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 EAN32345.1 - 0.14 11.6 0.0 5.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 EAN32345.1 - 0.19 12.1 0.0 3.9 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pyrophosphatase PF00719.19 EAN32347.1 - 6.9e-41 139.7 0.0 9e-41 139.3 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Bac_rhamnosid_C PF17390.2 EAN32347.1 - 0.15 11.9 0.1 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain Nuf2 PF03800.14 EAN32349.1 - 2.2e-23 82.9 0.0 6.6e-23 81.4 0.0 1.9 1 0 0 1 1 1 1 Nuf2 family Ribosomal_L9_C PF03948.14 EAN32349.1 - 0.013 16.0 0.3 0.13 12.7 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain TPR_MLP1_2 PF07926.12 EAN32349.1 - 0.043 13.9 27.0 0.35 10.9 7.8 3.7 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein HTH_Crp_2 PF13545.6 EAN32349.1 - 0.065 13.2 0.5 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain RWP-RK PF02042.15 EAN32349.1 - 0.078 13.0 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 RWP-RK domain DUF948 PF06103.11 EAN32349.1 - 0.18 12.1 10.4 1.7 8.9 0.1 4.3 2 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Med9 PF07544.13 EAN32349.1 - 0.23 11.6 20.6 0.67 10.1 0.3 4.5 2 2 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.9 EAN32349.1 - 0.24 10.5 29.2 0.82 8.7 16.3 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 EAN32349.1 - 0.47 10.5 26.0 0.037 14.1 2.2 4.1 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 EAN32349.1 - 2.3 8.7 14.9 21 5.6 3.0 5.2 3 1 1 4 4 4 0 Lipoprotein leucine-zipper DUF5082 PF16888.5 EAN32349.1 - 4.7 7.5 29.3 0.51 10.6 0.1 4.6 2 2 1 4 4 4 0 Domain of unknown function (DUF5082) Jnk-SapK_ap_N PF09744.9 EAN32349.1 - 7.4 6.8 31.4 0.047 13.9 13.3 2.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 WXG100 PF06013.12 EAN32349.1 - 9.8 6.5 8.4 9.2 6.6 1.3 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Filament PF00038.21 EAN32349.1 - 10 5.6 36.0 0.047 13.3 11.0 2.9 1 1 2 3 3 3 0 Intermediate filament protein Ribosomal_S8 PF00410.19 EAN32350.1 - 9.5e-21 74.1 0.0 1.2e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Pox_polyA_pol PF03296.13 EAN32351.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain TB2_DP1_HVA22 PF03134.19 EAN32352.1 - 1.6e-18 66.4 9.7 3.4e-18 65.4 7.2 2.2 2 0 0 2 2 2 1 TB2/DP1, HVA22 family MFS_1 PF07690.16 EAN32352.1 - 0.0077 15.2 1.6 0.014 14.3 1.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily RRM_1 PF00076.22 EAN32353.1 - 2.4e-15 56.1 0.2 3.3e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAN32353.1 - 0.00046 20.2 0.1 0.00091 19.2 0.1 1.4 1 0 0 1 1 1 1 RNA binding motif FYVE PF01363.21 EAN32354.1 - 0.00016 21.8 10.0 0.00016 21.8 10.0 1.8 2 0 0 2 2 2 1 FYVE zinc finger CdvA PF18822.1 EAN32354.1 - 0.0067 16.3 3.9 0.0067 16.3 3.9 2.1 2 1 1 3 3 3 1 CdvA-like coiled-coil domain TPR_MLP1_2 PF07926.12 EAN32354.1 - 0.038 14.0 0.3 0.082 13.0 0.3 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Rho_Binding PF08912.11 EAN32354.1 - 0.049 14.4 6.3 2 9.3 0.0 2.6 2 1 1 3 3 2 0 Rho Binding SKA2 PF16740.5 EAN32354.1 - 0.095 12.5 1.9 0.86 9.4 0.8 2.8 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 TBCA PF02970.16 EAN32354.1 - 0.19 12.1 3.0 0.23 11.8 1.5 1.9 1 1 0 1 1 1 0 Tubulin binding cofactor A UPF0242 PF06785.11 EAN32354.1 - 0.19 11.8 3.2 0.11 12.6 0.5 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus C1_1 PF00130.22 EAN32354.1 - 0.36 10.7 10.9 0.064 13.2 7.0 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Takusan PF04822.13 EAN32354.1 - 0.49 10.3 10.1 0.31 10.9 6.0 2.7 3 1 0 3 3 3 0 Takusan GAS PF13851.6 EAN32354.1 - 1 8.7 9.0 0.098 12.0 4.6 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 EAN32354.1 - 1 9.4 9.9 0.36 10.8 6.7 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.11 EAN32354.1 - 8.7 4.9 10.1 4.2 6.0 0.9 2.6 2 1 1 3 3 3 0 Weak chloroplast movement under blue light BRE1 PF08647.11 EAN32355.1 - 4.5e-06 26.6 11.0 5.7e-06 26.3 11.0 1.2 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 EAN32355.1 - 1.5e-05 25.3 17.2 1.7e-05 25.1 17.2 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) PI3K_P85_iSH2 PF16454.5 EAN32355.1 - 3.7e-05 23.4 5.9 3.7e-05 23.4 5.9 1.8 1 1 1 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF2156 PF09924.9 EAN32355.1 - 0.00062 18.9 1.8 0.00069 18.7 1.8 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) UPF0242 PF06785.11 EAN32355.1 - 0.0031 17.7 10.2 0.0037 17.4 10.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 EAN32355.1 - 0.0038 17.3 13.2 0.0044 17.1 13.2 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 EAN32355.1 - 0.0048 17.4 9.2 0.0066 16.9 9.2 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF16 OmpH PF03938.14 EAN32355.1 - 0.0055 17.1 11.7 0.007 16.7 11.7 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) IFT57 PF10498.9 EAN32355.1 - 0.0065 15.5 9.4 0.008 15.2 9.4 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 APG6_N PF17675.1 EAN32355.1 - 0.013 16.1 13.8 0.016 15.8 13.8 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3584 PF12128.8 EAN32355.1 - 0.013 13.1 9.2 0.014 12.9 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Taxilin PF09728.9 EAN32355.1 - 0.021 14.0 12.3 0.025 13.8 12.3 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Spc7 PF08317.11 EAN32355.1 - 0.022 13.7 10.7 0.026 13.4 10.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FPP PF05911.11 EAN32355.1 - 0.023 12.9 11.2 0.026 12.8 11.2 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 EAN32355.1 - 0.025 14.6 5.6 0.047 13.7 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ERM PF00769.19 EAN32355.1 - 0.027 14.3 12.6 0.029 14.2 12.6 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TMPIT PF07851.13 EAN32355.1 - 0.033 13.5 5.7 0.035 13.3 5.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein CLZ PF16526.5 EAN32355.1 - 0.04 14.3 14.1 0.13 12.7 7.4 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAUS-augmin3 PF14932.6 EAN32355.1 - 0.041 13.5 10.5 0.064 12.8 10.5 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Laminin_II PF06009.12 EAN32355.1 - 0.044 13.8 8.1 0.057 13.4 8.1 1.2 1 0 0 1 1 1 0 Laminin Domain II YlqD PF11068.8 EAN32355.1 - 0.046 14.1 10.2 0.056 13.8 10.2 1.0 1 0 0 1 1 1 0 YlqD protein TPR_MLP1_2 PF07926.12 EAN32355.1 - 0.048 13.7 12.5 0.076 13.1 12.5 1.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 EAN32355.1 - 0.049 14.1 10.3 0.065 13.7 10.3 1.2 1 0 0 1 1 1 0 Fez1 DUF948 PF06103.11 EAN32355.1 - 0.059 13.6 3.9 0.078 13.2 3.9 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tweety PF04906.13 EAN32355.1 - 0.066 11.9 1.7 0.073 11.7 1.7 1.1 1 0 0 1 1 1 0 Tweety Phage_GP20 PF06810.11 EAN32355.1 - 0.07 12.9 8.8 0.22 11.3 8.8 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 COG2 PF06148.11 EAN32355.1 - 0.073 13.2 7.6 0.12 12.5 7.6 1.4 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 HrpB7 PF09486.10 EAN32355.1 - 0.086 13.2 10.2 0.84 10.0 3.3 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) BST2 PF16716.5 EAN32355.1 - 0.088 13.4 9.8 0.12 13.0 9.8 1.2 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DLP_helical PF18709.1 EAN32355.1 - 0.095 11.9 5.5 0.089 12.0 4.7 1.4 1 1 0 1 1 1 0 Dynamin-like helical domain CENP-F_leu_zip PF10473.9 EAN32355.1 - 0.11 12.5 13.9 0.17 11.9 13.9 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_Maf PF03131.17 EAN32355.1 - 0.12 12.9 12.9 0.15 12.6 5.2 2.4 1 1 1 2 2 2 0 bZIP Maf transcription factor GAS PF13851.6 EAN32355.1 - 0.12 11.7 15.8 0.15 11.4 15.8 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PEARLI-4 PF05278.12 EAN32355.1 - 0.13 11.8 8.6 0.16 11.6 8.6 1.2 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) LXG PF04740.12 EAN32355.1 - 0.14 11.9 4.9 0.18 11.5 4.9 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF4200 PF13863.6 EAN32355.1 - 0.15 12.5 14.8 1.3 9.4 14.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF812 PF05667.11 EAN32355.1 - 0.16 10.8 10.8 0.19 10.6 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) BLOC1_2 PF10046.9 EAN32355.1 - 0.16 12.3 8.5 2.1 8.7 8.5 2.0 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EAN32355.1 - 0.19 12.2 5.8 0.52 10.8 3.8 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein WXG100 PF06013.12 EAN32355.1 - 0.19 12.0 6.0 4.1 7.7 2.4 2.8 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Phage_GPO PF05929.11 EAN32355.1 - 0.2 11.3 4.8 0.21 11.2 4.8 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FapA PF03961.13 EAN32355.1 - 0.21 10.1 9.0 0.23 10.0 9.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 EAN32355.1 - 0.22 9.4 6.0 0.22 9.4 6.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Uso1_p115_C PF04871.13 EAN32355.1 - 0.26 11.7 12.4 2 8.8 6.5 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HIP1_clath_bdg PF16515.5 EAN32355.1 - 0.37 11.4 13.4 0.66 10.6 13.4 1.4 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Syntaxin-6_N PF09177.11 EAN32355.1 - 0.37 11.4 8.4 1.1 9.8 8.4 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 EAN32355.1 - 0.37 10.3 8.3 0.45 10.0 8.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fzo_mitofusin PF04799.13 EAN32355.1 - 0.38 10.3 8.6 0.097 12.2 3.1 1.9 1 1 1 2 2 2 0 fzo-like conserved region Med21 PF11221.8 EAN32355.1 - 0.41 10.9 14.6 0.56 10.5 5.2 2.0 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Spc24 PF08286.11 EAN32355.1 - 0.48 10.7 13.3 1.1 9.5 8.0 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Cnn_1N PF07989.11 EAN32355.1 - 0.5 10.5 13.6 0.14 12.3 6.1 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Het-C PF07217.11 EAN32355.1 - 0.57 8.7 4.1 0.65 8.5 4.1 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Prefoldin_2 PF01920.20 EAN32355.1 - 0.68 9.9 13.3 6.4 6.8 2.4 2.6 1 1 1 2 2 2 0 Prefoldin subunit Prominin PF05478.11 EAN32355.1 - 0.84 7.5 6.0 1 7.2 6.0 1.1 1 0 0 1 1 1 0 Prominin DUF2968 PF11180.8 EAN32355.1 - 1 9.0 11.2 1.3 8.6 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Macoilin PF09726.9 EAN32355.1 - 1.1 7.8 11.3 1.1 7.7 11.3 1.0 1 0 0 1 1 1 0 Macoilin family Swi5 PF07061.11 EAN32355.1 - 1.1 9.3 7.8 22 5.2 7.8 2.2 1 1 0 1 1 1 0 Swi5 Atg14 PF10186.9 EAN32355.1 - 1.2 8.2 10.7 1.4 8.0 10.7 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APC_N_CC PF16689.5 EAN32355.1 - 1.2 9.3 10.3 0.42 10.7 2.5 2.5 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain LMBR1 PF04791.16 EAN32355.1 - 1.4 7.7 6.1 1.5 7.6 6.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.8 EAN32355.1 - 1.6 7.9 11.4 3.4 6.9 11.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 EAN32355.1 - 1.7 9.4 11.1 1.9 9.2 8.5 1.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF745 PF05335.13 EAN32355.1 - 1.7 8.4 7.0 2.2 8.0 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF724 PF05266.14 EAN32355.1 - 1.7 8.4 10.1 1.9 8.3 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Tho2 PF11262.8 EAN32355.1 - 2.2 7.4 7.5 2.6 7.1 7.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 EAN32355.1 - 3.4 7.0 9.2 5.5 6.3 9.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 EAN32355.1 - 3.6 8.0 9.4 3.1 8.2 2.8 2.5 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) FAM76 PF16046.5 EAN32355.1 - 5.2 6.3 8.5 6.1 6.1 8.5 1.1 1 0 0 1 1 1 0 FAM76 protein DivIC PF04977.15 EAN32355.1 - 5.5 6.8 13.4 2.1 8.2 5.9 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF3552 PF12072.8 EAN32355.1 - 6.6 6.1 17.8 15 4.9 17.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) JIP_LZII PF16471.5 EAN32355.1 - 7.3 6.8 16.3 17 5.7 12.2 2.2 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Bap31_Bap29_C PF18035.1 EAN32356.1 - 0.00031 20.7 7.9 0.61 10.1 0.4 3.7 2 1 1 3 3 3 2 Bap31/Bap29 cytoplasmic coiled-coil domain HOOK PF05622.12 EAN32356.1 - 0.0039 15.4 22.0 0.0079 14.4 22.0 1.5 1 0 0 1 1 1 1 HOOK protein HALZ PF02183.18 EAN32356.1 - 0.0047 17.1 20.9 0.32 11.3 0.0 6.6 7 0 0 7 7 7 2 Homeobox associated leucine zipper Filament PF00038.21 EAN32356.1 - 0.0077 15.9 21.0 0.028 14.0 13.9 2.9 1 1 1 2 2 2 1 Intermediate filament protein DivIC PF04977.15 EAN32356.1 - 0.017 14.9 19.1 0.34 10.7 0.2 4.9 2 1 1 4 4 4 0 Septum formation initiator DUF1664 PF07889.12 EAN32356.1 - 0.032 14.3 12.3 0.19 11.8 4.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EAN32356.1 - 0.037 14.3 5.7 0.17 12.2 0.8 3.5 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.6 EAN32356.1 - 0.054 13.2 29.7 0.025 14.3 9.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) KASH_CCD PF14662.6 EAN32356.1 - 0.054 13.3 33.5 0.0091 15.8 22.3 3.2 2 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH Laminin_II PF06009.12 EAN32356.1 - 0.089 12.8 16.2 1.2 9.2 2.2 2.8 1 1 1 2 2 2 0 Laminin Domain II GAS PF13851.6 EAN32356.1 - 0.17 11.3 31.4 0.087 12.2 5.8 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 EAN32356.1 - 0.2 12.3 28.3 1.1 9.9 5.5 4.7 2 1 2 4 4 4 0 Initiation control protein YabA Shugoshin_N PF07558.11 EAN32356.1 - 0.35 10.8 8.6 16 5.4 0.1 4.6 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region TACC_C PF05010.14 EAN32356.1 - 0.38 10.5 29.9 0.57 9.9 7.4 2.8 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4407 PF14362.6 EAN32356.1 - 0.4 10.0 15.6 0.49 9.7 1.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MAD PF05557.13 EAN32356.1 - 1.3 7.3 33.2 0.21 9.9 27.3 2.2 2 1 1 3 3 3 0 Mitotic checkpoint protein DUF2730 PF10805.8 EAN32356.1 - 1.4 9.0 11.6 0.27 11.4 1.1 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) CCDC84 PF14968.6 EAN32356.1 - 1.6 8.3 11.2 0.38 10.3 7.8 1.7 2 0 0 2 2 1 0 Coiled coil protein 84 ATG16 PF08614.11 EAN32356.1 - 2 8.6 30.1 0.33 11.2 19.8 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) LPP PF04728.13 EAN32356.1 - 2.1 8.8 13.2 3.1 8.3 0.0 4.6 4 2 1 5 5 4 0 Lipoprotein leucine-zipper WXG100 PF06013.12 EAN32356.1 - 2.6 8.3 8.6 12 6.2 1.3 3.9 2 2 1 3 3 3 0 Proteins of 100 residues with WXG TPR_MLP1_2 PF07926.12 EAN32356.1 - 5.7 7.0 31.9 0.19 11.8 13.5 4.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 EAN32356.1 - 7.8 6.5 21.5 0.18 11.8 6.0 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMEM215 PF15746.5 EAN32357.1 - 0.045 13.2 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 TMEM215 family UPF0020 PF01170.18 EAN32358.1 - 0.0055 16.4 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Glycoprot_B_PH2 PF17417.2 EAN32358.1 - 0.053 13.9 8.8 7.9 6.9 0.0 4.0 3 0 0 3 3 3 0 Herpesvirus Glycoprotein B PH-like domain DXP_redisom_C PF08436.12 EAN32359.1 - 2.2e-34 117.4 0.0 4.9e-34 116.3 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXP_reductoisom PF02670.16 EAN32359.1 - 2.1e-31 109.3 0.0 3.6e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 EAN32359.1 - 6.1e-29 100.6 0.0 1.1e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain Kin17_mid PF10357.9 EAN32360.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Pep3_Vps18 PF05131.14 EAN32361.1 - 5.7e-16 58.7 0.1 1.1e-15 57.7 0.1 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family zf-RING_2 PF13639.6 EAN32361.1 - 2e-05 24.9 1.0 2e-05 24.9 1.0 2.2 2 0 0 2 2 2 1 Ring finger domain Vps39_2 PF10367.9 EAN32361.1 - 2.4e-05 24.7 0.4 2.4e-05 24.7 0.4 1.8 2 0 0 2 2 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 EAN32361.1 - 7.8e-05 22.4 1.1 7.8e-05 22.4 1.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN32361.1 - 9.1e-05 22.4 0.9 0.00034 20.6 0.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EAN32361.1 - 0.00038 20.1 4.8 0.00038 20.1 4.8 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EAN32361.1 - 0.009 16.3 0.2 0.009 16.3 0.2 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAN32361.1 - 0.016 15.1 0.5 0.016 15.1 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAN32361.1 - 0.022 14.7 1.1 0.022 14.7 1.1 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EAN32361.1 - 0.034 14.0 0.4 0.034 14.0 0.4 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAN32361.1 - 0.093 12.6 1.5 0.32 10.9 1.5 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EAN32361.1 - 0.35 10.5 3.7 0.15 11.7 0.8 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 EAN32361.1 - 0.61 10.2 2.3 0.44 10.7 0.2 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger Myb_DNA-bind_6 PF13921.6 EAN32362.1 - 0.00026 21.2 0.4 0.0007 19.8 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain IGR PF09597.10 EAN32362.1 - 0.0017 18.4 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 IGR protein motif SANT_DAMP1_like PF16282.5 EAN32362.1 - 0.0047 17.1 0.1 0.012 15.8 0.1 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 zf-SNAP50_C PF12251.8 EAN32363.1 - 1.8e-38 132.2 9.7 3.1e-38 131.5 9.7 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Ribosomal_L27e PF01777.18 EAN32364.1 - 2.2e-29 101.6 6.2 3.2e-29 101.1 6.2 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family C1-set PF07654.15 EAN32364.1 - 0.036 14.4 0.1 0.061 13.7 0.1 1.4 1 1 0 1 1 1 0 Immunoglobulin C1-set domain KOW PF00467.29 EAN32364.1 - 0.088 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 KOW motif NOP5NT PF08156.13 EAN32364.1 - 0.095 13.1 1.0 1 9.8 0.1 2.1 2 0 0 2 2 2 0 NOP5NT (NUC127) domain PAZ_siRNAbind PF12212.8 EAN32365.1 - 0.039 13.8 0.5 0.082 12.7 0.5 1.5 1 0 0 1 1 1 0 PAZ domain MRP-S34 PF16053.5 EAN32365.1 - 0.097 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 Endonuc_BglI PF14562.6 EAN32365.1 - 0.1 11.6 0.9 0.17 11.0 0.9 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglI Ribosomal_L29e PF01779.17 EAN32366.1 - 2e-21 76.0 9.9 2e-21 76.0 9.9 1.5 2 0 0 2 2 2 1 Ribosomal L29e protein family ECR1_N PF14382.6 EAN32367.1 - 6.2e-10 38.7 0.0 1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EAN32367.1 - 8.8e-09 35.6 0.1 2e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 EAN32367.1 - 0.061 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF5422 PF17459.2 EAN32367.1 - 0.11 12.6 0.1 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5422) Ribosomal_L5e PF17144.4 EAN32368.1 - 3.6e-82 274.2 1.1 5.6e-81 270.3 0.5 2.1 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EAN32368.1 - 9.1e-33 113.1 3.9 9.1e-33 113.1 3.9 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF1476 PF07345.11 EAN32368.1 - 0.065 13.6 0.1 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta EAL PF00563.20 EAN32368.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 EAL domain Ribosomal_L7Ae PF01248.26 EAN32369.1 - 1.4e-22 79.2 0.7 2.4e-22 78.4 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Las1 PF04031.13 EAN32371.1 - 0.00043 20.4 0.0 0.00051 20.2 0.0 1.1 1 0 0 1 1 1 1 Las1-like zf-CCCH PF00642.24 EAN32373.1 - 5.4e-10 38.9 8.2 1.7e-06 27.8 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAN32373.1 - 0.00066 19.7 16.3 0.17 12.0 5.7 3.1 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 EAN32373.1 - 0.00072 19.7 6.2 0.05 13.8 0.5 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 EAN32373.1 - 0.0039 17.6 0.9 0.0039 17.6 0.9 2.5 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EAN32373.1 - 0.018 15.8 7.8 0.53 11.0 1.6 2.5 1 1 1 2 2 2 0 Torus domain zf-CCCH_4 PF18044.1 EAN32373.1 - 0.03 14.1 13.6 0.49 10.3 2.4 2.6 2 1 0 2 2 2 0 CCCH-type zinc finger DUF2286 PF10051.9 EAN32373.1 - 0.065 13.0 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2286) rpo30_N PF12410.8 EAN32373.1 - 0.16 11.9 5.4 0.51 10.2 0.6 2.6 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit SF-assemblin PF06705.11 EAN32373.1 - 2.6 7.3 7.4 0.6 9.4 0.4 2.6 3 0 0 3 3 3 0 SF-assemblin/beta giardin zf-C3H1 PF10650.9 EAN32373.1 - 5.1 6.9 5.9 0.61 9.9 1.2 2.0 2 0 0 2 2 2 0 Putative zinc-finger domain PrmA PF06325.13 EAN32374.1 - 2.8e-10 40.1 0.0 4.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EAN32374.1 - 1.2e-09 38.7 0.0 3.5e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAN32374.1 - 6.3e-08 32.6 0.0 1.7e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAN32374.1 - 2.9e-07 31.0 0.0 8.8e-07 29.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAN32374.1 - 9.1e-07 28.9 0.0 2e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAN32374.1 - 5.5e-06 26.0 0.1 9.3e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EAN32374.1 - 5.6e-05 22.6 0.4 0.00017 21.1 0.1 1.9 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 EAN32374.1 - 8.2e-05 22.4 0.1 0.00014 21.6 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EAN32374.1 - 0.00017 22.3 0.0 0.00044 20.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EAN32374.1 - 0.00031 19.8 0.0 0.00051 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 EAN32374.1 - 0.0022 17.9 0.1 0.0044 16.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EAN32374.1 - 0.087 12.7 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Ribosomal_L21e PF01157.18 EAN32375.1 - 1.1e-43 147.1 4.9 1.1e-43 147.1 4.9 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e NAC PF01849.18 EAN32376.1 - 2.1e-18 66.0 0.0 4.3e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 NAC domain AAA_18 PF13238.6 EAN32376.1 - 0.14 12.7 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain WW PF00397.26 EAN32377.1 - 2e-08 34.1 2.9 3.8e-08 33.3 2.2 1.8 2 0 0 2 2 2 1 WW domain RPW8 PF05659.11 EAN32377.1 - 0.019 14.7 0.4 0.033 13.9 0.4 1.4 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Tektin PF03148.14 EAN32377.1 - 0.022 13.5 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Tektin family DUF4795 PF16043.5 EAN32377.1 - 0.042 13.4 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF573 PF04504.14 EAN32377.1 - 0.11 13.1 1.1 1.1 10.0 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF573 Sec5 PF15469.6 EAN32377.1 - 0.34 10.7 4.7 0.21 11.4 1.8 2.1 2 1 0 2 2 2 0 Exocyst complex component Sec5 Ribosomal_L16 PF00252.18 EAN32379.1 - 3.4e-41 140.3 0.1 4.6e-41 139.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e ribosomal_L24 PF17136.4 EAN32380.1 - 1.8e-13 50.7 0.0 3.3e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 EAN32380.1 - 9.1e-06 25.4 2.2 1.5e-05 24.8 2.2 1.4 1 0 0 1 1 1 1 KOW motif Rep_fac-A_C PF08646.10 EAN32381.1 - 2e-33 115.2 0.3 6.4e-33 113.5 0.3 1.9 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EAN32381.1 - 6e-19 67.8 1.8 6.7e-18 64.4 1.5 2.6 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 EAN32381.1 - 4.1e-11 42.7 2.6 4.7e-10 39.3 0.2 3.4 2 1 1 3 3 3 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EAN32381.1 - 0.00042 20.1 6.9 0.076 12.7 6.7 2.2 1 1 1 2 2 2 2 Cell division control protein 24, OB domain 3 His_Me_b4a2 PF18275.1 EAN32381.1 - 0.002 18.2 2.6 1.2 9.3 0.1 2.6 2 0 0 2 2 2 2 His-Me finger endonuclease beta4-alpha2 domain Prok-RING_1 PF14446.6 EAN32381.1 - 0.027 14.4 1.9 0.055 13.4 1.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 A2L_zn_ribbon PF08792.10 EAN32381.1 - 0.14 11.9 4.0 0.1 12.4 1.9 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain DnaJ_C PF01556.18 EAN32382.1 - 1.8e-34 118.9 0.0 2.6e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAN32382.1 - 1.7e-23 82.5 0.9 2.9e-23 81.7 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EAN32382.1 - 5.8e-11 42.6 13.9 1.3e-10 41.5 13.9 1.6 1 0 0 1 1 1 1 DnaJ central domain Transcrip_act PF04949.13 EAN32382.1 - 0.022 14.6 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Transcriptional activator Anti-TRAP PF15777.5 EAN32382.1 - 0.29 11.1 18.3 1.2 9.2 6.2 3.1 2 1 2 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EAN32382.1 - 7.5 6.6 9.2 2.9 8.0 1.1 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Peptidase_C1 PF00112.23 EAN32383.1 - 5.2e-50 170.6 3.2 5.2e-50 170.6 3.2 2.3 3 0 0 3 3 3 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAN32383.1 - 6e-11 42.6 6.7 6e-11 42.6 6.7 2.6 2 1 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAN32383.1 - 1.2e-05 24.3 0.2 0.00035 19.5 0.1 2.2 2 0 0 2 2 2 1 Peptidase C1-like family DUF3671 PF12420.8 EAN32383.1 - 0.0083 16.2 6.5 0.018 15.2 0.5 2.8 2 0 0 2 2 2 1 Protein of unknown function DUF4808 PF16066.5 EAN32383.1 - 0.27 11.8 0.0 0.27 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) Synaptobrevin PF00957.21 EAN32383.1 - 0.38 10.6 4.0 1.1 9.1 1.0 2.4 2 0 0 2 2 2 0 Synaptobrevin Peptidase_C1 PF00112.23 EAN32384.1 - 3.2e-47 161.4 6.3 6.2e-47 160.5 6.3 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAN32384.1 - 1.4e-08 35.0 3.1 5.2e-08 33.2 3.1 2.1 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAN32384.1 - 2.3e-06 26.7 1.2 3.4e-05 22.8 0.5 2.3 2 0 0 2 2 2 1 Peptidase C1-like family HRG PF16954.5 EAN32384.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene UPF0242 PF06785.11 EAN32384.1 - 5 7.2 6.9 2.9 7.9 3.9 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_C1 PF00112.23 EAN32385.1 - 9e-48 163.2 4.7 1.6e-47 162.4 4.7 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAN32385.1 - 1.1e-08 35.3 3.1 3.8e-08 33.7 3.1 2.0 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAN32385.1 - 9.3e-06 24.7 3.3 4.5e-05 22.4 0.5 2.4 2 1 0 2 2 2 1 Peptidase C1-like family Sigma_reg_N PF13800.6 EAN32385.1 - 0.00032 20.9 4.6 0.00048 20.4 3.2 2.0 2 0 0 2 2 2 1 Sigma factor regulator N-terminal DUF2207 PF09972.9 EAN32386.1 - 0.39 9.4 2.6 0.39 9.4 2.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 EAN32386.1 - 2.4 7.8 6.0 2.9 7.5 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) zf-C2H2_2 PF12756.7 EAN32387.1 - 6.2e-26 90.7 8.6 1.5e-22 79.8 6.2 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) HNH PF01844.23 EAN32387.1 - 0.032 14.4 4.6 0.08 13.1 1.8 2.5 2 0 0 2 2 2 0 HNH endonuclease zf-C2H2_jaz PF12171.8 EAN32387.1 - 0.062 13.6 13.2 0.17 12.2 3.8 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EAN32387.1 - 0.076 13.9 7.5 1.5 9.9 0.7 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger CWC25 PF12542.8 EAN32387.1 - 0.12 13.3 2.9 0.33 11.9 0.3 2.6 2 0 0 2 2 2 0 Pre-mRNA splicing factor FYVE PF01363.21 EAN32387.1 - 4.6 7.4 5.9 2.5 8.3 0.5 2.4 2 0 0 2 2 2 0 FYVE zinc finger DUF5606 PF18347.1 EAN32389.1 - 0.072 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5606) YIF1 PF03878.15 EAN32391.1 - 2.3e-06 27.3 0.1 4.4e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 YIF1 LSM PF01423.22 EAN32392.1 - 1.5e-14 53.4 1.0 1.8e-14 53.2 1.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EAN32392.1 - 0.0013 18.8 0.6 0.0032 17.6 0.6 1.6 1 1 0 1 1 1 1 RimP C-terminal SH3 domain RNase_H2_suC PF08615.11 EAN32392.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) AMP-binding PF00501.28 EAN32393.1 - 2e-63 214.4 0.0 2.9e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAN32393.1 - 0.00012 23.0 0.1 0.00024 22.0 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HUN PF08729.10 EAN32396.1 - 2.6e-10 40.1 2.2 7.1e-10 38.7 2.2 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UCH PF00443.29 EAN32397.1 - 2.8e-24 86.0 0.0 3.1e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAN32397.1 - 4.8e-11 42.8 0.2 8.5e-11 42.0 0.2 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MCM PF00493.23 EAN32399.1 - 2.7e-98 327.5 0.0 5.4e-98 326.5 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EAN32399.1 - 2.9e-34 117.6 2.4 5.4e-34 116.8 2.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EAN32399.1 - 1.2e-25 89.7 0.2 3.3e-25 88.3 0.2 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 EAN32399.1 - 3.8e-09 36.7 2.4 5.4e-09 36.2 0.4 2.3 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 EAN32399.1 - 1.8e-05 24.2 0.0 6.3e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAN32399.1 - 0.0025 17.8 0.1 0.013 15.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Zn-ribbon_8 PF09723.10 EAN32399.1 - 0.024 14.8 0.9 0.06 13.5 0.9 1.7 1 0 0 1 1 1 0 Zinc ribbon domain AAA_3 PF07726.11 EAN32399.1 - 0.032 14.1 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TF_Zn_Ribbon PF08271.12 EAN32399.1 - 0.087 12.3 0.2 0.4 10.2 0.2 2.1 1 0 0 1 1 1 0 TFIIB zinc-binding PIG-X PF08320.12 EAN32401.1 - 7.7e-08 32.5 0.3 0.00054 19.9 0.1 2.6 2 0 0 2 2 2 2 PIG-X / PBN1 SPG48 PF14764.6 EAN32401.1 - 0.012 16.1 0.2 0.032 14.7 0.2 1.8 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking SMC_N PF02463.19 EAN32403.1 - 3.6e-49 167.2 79.3 4.9e-48 163.5 79.3 3.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EAN32403.1 - 6e-22 78.2 0.0 1.6e-21 76.8 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EAN32403.1 - 3.5e-13 50.0 19.0 4.4e-07 30.0 0.0 4.4 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAN32403.1 - 1.2e-12 48.7 13.0 1.2e-12 48.7 13.0 8.2 2 2 2 5 5 3 1 AAA domain AAA_29 PF13555.6 EAN32403.1 - 1.5e-06 27.8 0.0 3.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Lebercilin PF15619.6 EAN32403.1 - 4.1e-05 23.3 30.3 4.1e-05 23.3 30.3 7.1 4 2 2 7 7 7 1 Ciliary protein causing Leber congenital amaurosis disease MscS_porin PF12795.7 EAN32403.1 - 0.0014 18.2 104.5 0.0071 15.9 5.7 7.1 5 3 1 6 6 5 4 Mechanosensitive ion channel porin domain AAA_13 PF13166.6 EAN32403.1 - 0.0014 17.4 24.1 0.0014 17.4 24.1 6.0 4 2 2 6 6 6 2 AAA domain GAS PF13851.6 EAN32403.1 - 0.0038 16.6 27.2 0.0038 16.6 27.2 8.2 3 2 4 7 7 7 2 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 EAN32403.1 - 0.05 14.1 0.0 0.05 14.1 0.0 7.1 4 2 0 4 4 2 0 ABC transporter TolA_bind_tri PF16331.5 EAN32403.1 - 0.11 12.6 0.1 0.11 12.6 0.1 9.6 8 2 2 11 11 10 0 TolA binding protein trimerisation AAA_16 PF13191.6 EAN32403.1 - 0.35 11.2 2.0 38 4.6 0.0 4.3 4 1 0 4 4 4 0 AAA ATPase domain ATG16 PF08614.11 EAN32403.1 - 2.3 8.4 101.0 0.14 12.4 14.4 7.3 3 2 3 6 6 5 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EAN32403.1 - 7.6 5.3 124.8 0.0058 15.5 14.5 7.4 3 2 5 8 8 8 0 Spc7 kinetochore protein RNA_pol_Rpc4 PF05132.14 EAN32404.1 - 6.4e-18 65.6 0.0 1.6e-16 61.1 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase III RPC4 Kelch_4 PF13418.6 EAN32405.1 - 3.1e-22 78.3 7.1 2.7e-08 33.7 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EAN32405.1 - 1e-16 60.7 1.3 1.4e-06 28.4 0.0 5.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EAN32405.1 - 5.2e-14 51.9 12.1 0.0011 19.0 0.3 6.9 7 1 0 7 7 7 4 Kelch motif Kelch_6 PF13964.6 EAN32405.1 - 1e-12 47.8 6.5 0.00011 22.3 0.0 5.0 5 0 0 5 5 5 3 Kelch motif HATPase_c_3 PF13589.6 EAN32405.1 - 2.8e-11 43.4 0.0 7.5e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_1 PF01344.25 EAN32405.1 - 2.5e-10 39.8 5.3 1.6e-05 24.4 0.1 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 EAN32405.1 - 9.2e-09 34.9 1.4 3.7e-05 23.5 0.1 3.3 3 0 0 3 3 3 2 Kelch motif HATPase_c PF02518.26 EAN32405.1 - 1.8e-06 28.4 0.0 4.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CCCH PF00642.24 EAN32406.1 - 0.00082 19.2 15.2 0.03 14.2 1.5 4.0 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAN32406.1 - 0.061 13.4 0.5 0.061 13.4 0.5 5.3 5 1 0 5 5 5 0 Zinc finger domain Fer4_20 PF14691.6 EAN32406.1 - 0.31 10.8 4.3 0.74 9.6 4.3 1.7 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster zf-CCCH_4 PF18044.1 EAN32406.1 - 1.8 8.4 16.4 0.72 9.7 0.3 4.2 4 1 0 4 4 4 0 CCCH-type zinc finger DER1 PF04511.15 EAN32407.1 - 3.7e-42 144.4 15.1 4.2e-42 144.2 15.1 1.0 1 0 0 1 1 1 1 Der1-like family CDC27 PF09507.10 EAN32408.1 - 4.3 6.6 28.9 5.3 6.3 28.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DEAD PF00270.29 EAN32409.1 - 2.3e-42 144.8 0.2 4.2e-42 143.9 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN32409.1 - 5e-32 110.5 0.6 2.2e-31 108.5 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN32409.1 - 1.2e-05 25.4 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EAN32409.1 - 0.00035 20.5 0.0 0.00063 19.6 0.0 1.3 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.6 EAN32409.1 - 0.00061 19.6 0.0 0.00094 19.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAN32409.1 - 0.0011 19.3 0.1 0.0026 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain tRNA-synt_1b PF00579.25 EAN32409.1 - 0.0046 16.3 0.3 0.0089 15.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) CMS1 PF14617.6 EAN32409.1 - 0.013 14.8 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit HTH_Tnp_1_2 PF13022.6 EAN32409.1 - 0.05 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase SWI2_SNF2 PF18766.1 EAN32409.1 - 0.1 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase tRNA_bind PF01588.20 EAN32410.1 - 2.1e-27 95.0 0.1 3.7e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 EAN32410.1 - 1.4e-09 38.0 0.0 3.4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAN32410.1 - 9e-08 32.2 0.2 2.9e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAN32410.1 - 0.00015 21.8 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EAN32410.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain OHA PF14418.6 EAN32411.1 - 1.5e-23 82.3 0.0 4e-23 81.0 0.0 1.7 1 0 0 1 1 1 1 OST-HTH Associated domain OST-HTH PF12872.7 EAN32411.1 - 6.2e-10 38.8 0.1 1.8e-09 37.3 0.1 1.8 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Tobravirus_2B PF05271.11 EAN32411.1 - 0.03 14.2 0.2 13 5.7 0.1 3.3 3 0 0 3 3 3 0 Tobravirus 2B protein SR-25 PF10500.9 EAN32411.1 - 0.29 10.7 3.7 0.43 10.1 3.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein His_Phos_1 PF00300.22 EAN32412.1 - 0.017 14.8 0.0 21 4.7 0.0 3.4 3 1 0 3 3 3 0 Histidine phosphatase superfamily (branch 1) DUF4655 PF15548.6 EAN32413.1 - 0.35 9.8 0.7 0.49 9.3 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) Asp_protease PF09668.10 EAN32415.1 - 2.1e-49 166.4 0.5 3.4e-49 165.7 0.5 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EAN32415.1 - 3.3e-21 75.6 0.2 7.6e-21 74.5 0.2 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EAN32415.1 - 2.7e-11 43.9 0.2 6e-11 42.8 0.2 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 EAN32415.1 - 3.6e-06 27.2 0.1 8.1e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease ubiquitin PF00240.23 EAN32415.1 - 6.3e-06 25.9 0.0 3e-05 23.7 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.11 EAN32415.1 - 9.3e-05 22.2 0.2 0.00021 21.1 0.2 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 EAN32415.1 - 0.00011 21.9 0.2 0.0002 21.0 0.2 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase Rad60-SLD PF11976.8 EAN32415.1 - 0.00079 19.2 0.0 0.0024 17.7 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 EAN32415.1 - 0.015 15.7 0.1 0.075 13.5 0.1 2.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 TBK1_ULD PF18396.1 EAN32415.1 - 0.071 13.1 0.0 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain FAST_1 PF06743.15 EAN32417.1 - 7e-06 25.9 9.7 0.28 11.2 0.0 4.7 3 1 0 4 4 4 4 FAST kinase-like protein, subdomain 1 WIYLD PF10440.9 EAN32417.1 - 0.079 12.8 0.2 0.43 10.4 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Mic1 PF07035.12 EAN32418.1 - 6.6e-11 42.2 6.3 1.3e-10 41.2 6.3 1.5 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like PK PF00224.21 EAN32420.1 - 2.3e-87 293.1 0.0 1e-48 166.0 0.1 2.2 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 EAN32420.1 - 0.0032 17.7 0.0 0.0081 16.4 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Hemocyanin_N PF03722.14 EAN32420.1 - 0.02 15.4 0.1 0.059 13.9 0.1 1.7 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain Pkinase PF00069.25 EAN32425.1 - 2e-61 207.7 0.0 2.8e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32425.1 - 5.8e-34 117.5 0.0 9.7e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAN32425.1 - 0.0017 17.7 0.0 0.019 14.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAN32425.1 - 0.085 12.8 0.1 3.2 7.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_C1 PF00112.23 EAN32426.1 - 1.3e-29 103.9 0.6 8.2e-29 101.2 0.0 2.2 2 1 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EAN32426.1 - 1.1e-09 38.6 14.4 2.4e-09 37.5 14.4 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EAN32426.1 - 4.1e-05 22.5 2.7 0.0003 19.7 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Mito_carr PF00153.27 EAN32427.1 - 4.7e-67 222.0 6.1 2.7e-24 84.9 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ubiquitin PF00240.23 EAN32428.1 - 4.4e-25 87.2 7.8 5.9e-25 86.8 2.7 2.2 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EAN32428.1 - 1.9e-17 62.8 2.4 3e-17 62.2 2.4 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EAN32428.1 - 4.2e-06 26.7 2.2 0.0072 16.3 1.6 2.7 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAN32428.1 - 0.00016 21.7 0.3 0.00093 19.3 0.2 2.2 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAN32428.1 - 0.004 17.6 0.8 0.016 15.6 0.8 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EAN32428.1 - 0.02 15.2 2.9 0.029 14.7 1.9 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 EAN32428.1 - 0.022 14.7 0.2 0.036 14.0 0.2 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain OapA PF04225.12 EAN32428.1 - 0.1 12.7 1.5 9.4 6.4 0.3 2.2 2 0 0 2 2 2 0 Opacity-associated protein A LysM-like domain Dynamin_M PF01031.20 EAN32429.1 - 1.7e-79 267.0 0.8 7.3e-79 265.0 0.8 2.1 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EAN32429.1 - 1.3e-48 165.2 0.0 3.3e-48 163.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EAN32429.1 - 6.9e-31 106.3 4.4 4.1e-30 103.8 4.6 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EAN32429.1 - 1.6e-05 25.0 0.0 7.3e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Condensin2nSMC PF12422.8 EAN32429.1 - 0.037 14.2 4.0 0.13 12.5 0.4 3.0 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit AAA_16 PF13191.6 EAN32429.1 - 0.19 12.1 0.0 0.58 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ERCC3_RAD25_C PF16203.5 EAN32430.1 - 1.7e-110 368.0 0.4 1.7e-110 368.0 0.4 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EAN32430.1 - 4e-28 98.1 0.0 9.9e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN32430.1 - 4.5e-17 62.6 1.0 8.4e-17 61.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAN32430.1 - 1.3e-11 44.8 0.5 1e-10 41.9 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EAN32430.1 - 4e-06 25.8 0.1 6.9e-06 25.0 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_34 PF13872.6 EAN32430.1 - 0.0086 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Cation_ATPase_N PF00690.26 EAN32430.1 - 0.16 11.7 0.2 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Radical_SAM_C PF16199.5 EAN32432.1 - 1.9e-20 72.6 0.1 3.9e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EAN32432.1 - 1.2e-15 58.3 0.1 2.8e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EAN32432.1 - 0.15 12.3 0.3 0.58 10.4 0.2 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family HSP70 PF00012.20 EAN32434.1 - 9.3e-255 846.4 7.3 1e-254 846.3 7.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAN32434.1 - 3.4e-16 59.0 0.2 8.8e-15 54.3 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EAN32434.1 - 0.00044 20.6 4.1 0.67 10.4 0.1 3.8 3 2 0 3 3 3 1 Cell division protein FtsA DDR PF08841.10 EAN32434.1 - 0.0023 17.0 0.8 0.12 11.3 0.4 2.4 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 EAN32434.1 - 0.059 12.6 2.1 0.27 10.4 0.7 2.6 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase APP_N PF02177.16 EAN32434.1 - 0.097 13.0 0.8 0.27 11.6 0.8 1.7 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding FGGY_C PF02782.16 EAN32434.1 - 0.15 11.7 0.0 0.53 10.0 0.0 1.9 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Mago_nashi PF02792.14 EAN32434.1 - 0.17 12.0 1.7 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Mago nashi protein zf-C3HC4_3 PF13920.6 EAN32435.1 - 3e-09 36.6 10.3 3e-09 36.6 10.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAN32435.1 - 5.3e-09 35.8 11.0 5.3e-09 35.8 11.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAN32435.1 - 1.2e-08 34.6 17.8 1.3e-08 34.6 12.2 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAN32435.1 - 1.7e-07 31.5 11.5 1.7e-07 31.5 11.5 2.7 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 EAN32435.1 - 2.5e-07 30.5 12.6 2.5e-07 30.5 12.6 2.8 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EAN32435.1 - 6.4e-07 29.1 10.0 2.3e-06 27.3 10.0 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EAN32435.1 - 8.8e-07 28.8 10.7 2.5e-06 27.4 10.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EAN32435.1 - 3.9e-05 23.7 8.0 3.9e-05 23.7 8.0 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EAN32435.1 - 0.00066 19.4 7.4 0.0024 17.6 7.4 2.1 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FPP PF05911.11 EAN32435.1 - 0.00073 17.9 37.4 0.00073 17.9 37.4 1.7 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil zf-rbx1 PF12678.7 EAN32435.1 - 0.001 19.3 7.6 0.005 17.1 7.6 2.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain Filament PF00038.21 EAN32435.1 - 0.042 13.4 28.1 0.19 11.3 23.4 3.2 1 1 1 2 2 2 0 Intermediate filament protein Hrs_helical PF12210.8 EAN32435.1 - 0.099 13.2 6.3 0.11 13.0 0.4 3.2 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate zf-RING_6 PF14835.6 EAN32435.1 - 0.11 12.3 4.2 0.34 10.8 4.2 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein EzrA PF06160.12 EAN32435.1 - 0.18 9.9 26.7 0.097 10.8 0.7 3.4 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA zf-UDP PF14569.6 EAN32435.1 - 0.33 11.1 8.6 0.063 13.4 4.0 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger Gp-FAR-1 PF05823.12 EAN32435.1 - 0.92 9.9 16.8 0.45 10.8 6.3 3.1 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Phosphoesterase PF04185.14 EAN32435.1 - 1.2 8.3 5.7 2.2 7.4 5.7 1.4 1 1 0 1 1 1 0 Phosphoesterase family zf-Nse PF11789.8 EAN32435.1 - 2.4 8.0 10.9 0.53 10.1 6.6 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF2605 PF10792.9 EAN32435.1 - 2.9 7.9 5.5 6 6.9 1.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2605) HALZ PF02183.18 EAN32435.1 - 4.2 7.7 13.3 13 6.1 1.3 4.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 EAN32435.1 - 4.4 7.5 6.6 2.7 8.1 0.1 3.6 3 0 0 3 3 3 0 Basic region leucine zipper Exonuc_VII_L PF02601.15 EAN32435.1 - 4.9 6.6 22.8 2.7 7.5 6.4 2.6 1 1 0 2 2 2 0 Exonuclease VII, large subunit zf-RING_11 PF17123.5 EAN32435.1 - 5.1 6.9 8.8 16 5.3 8.8 2.0 1 0 0 1 1 1 0 RING-like zinc finger bZIP_1 PF00170.21 EAN32435.1 - 5.4 7.2 20.1 7.6 6.7 0.1 5.3 4 2 4 8 8 7 0 bZIP transcription factor SKA2 PF16740.5 EAN32435.1 - 7.3 6.4 14.9 4.9 7.0 3.6 4.1 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 2 zf-ANAPC11 PF12861.7 EAN32435.1 - 9.7 6.3 9.0 0.81 9.8 3.7 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CPSF100_C PF13299.6 EAN32436.1 - 0.0084 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EAN32437.1 - 1.4e-06 28.5 0.1 2.4e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EAN32437.1 - 4.4e-06 26.3 0.0 8.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Chromadorea_ALT PF05535.12 EAN32437.1 - 0.1 12.8 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Chromadorea ALT protein ComC PF03047.14 EAN32438.1 - 0.15 11.9 2.1 0.17 11.7 0.4 2.1 2 0 0 2 2 2 0 COMC family UCH_C PF18031.1 EAN32438.1 - 0.72 9.8 5.5 1.7 8.6 5.5 1.6 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases AAA_23 PF13476.6 EAN32440.1 - 1.6e-16 61.4 78.8 0.0007 20.2 75.8 5.3 1 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 EAN32440.1 - 3.1e-15 56.2 16.2 2.2e-14 53.4 16.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EAN32440.1 - 1e-06 28.7 16.3 1e-06 28.7 16.3 4.4 1 1 2 3 3 1 1 AAA ATPase domain AAA_21 PF13304.6 EAN32440.1 - 8.8e-05 22.4 8.6 0.00077 19.3 0.4 3.3 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAN32440.1 - 0.00023 20.8 0.0 0.00059 19.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EAN32440.1 - 0.0037 17.4 0.0 0.013 15.7 0.0 1.9 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 EAN32440.1 - 0.0061 16.5 0.2 0.12 12.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_27 PF13514.6 EAN32440.1 - 0.011 15.3 2.5 0.02 14.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EAN32440.1 - 0.012 16.1 1.9 0.012 16.1 1.9 4.5 4 3 0 4 4 3 0 ABC transporter AAA_16 PF13191.6 EAN32440.1 - 0.014 15.8 0.5 0.11 12.9 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 EAN32440.1 - 0.045 13.7 1.0 0.25 11.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) CytoC_RC PF02276.18 EAN32440.1 - 0.11 11.9 0.4 0.38 10.1 0.1 1.9 2 0 0 2 2 2 0 Photosynthetic reaction centre cytochrome C subunit AAA_33 PF13671.6 EAN32440.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.6 EAN32440.1 - 0.53 10.6 0.0 0.53 10.6 0.0 3.9 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EAN32440.1 - 3.1 8.3 10.1 1.7 9.2 0.1 4.0 4 0 0 4 4 4 0 AAA domain NPR1_interact PF15699.5 EAN32441.1 - 0.0015 19.2 1.3 0.0015 19.1 0.3 1.5 2 0 0 2 2 2 1 NPR1 interacting UQ_con PF00179.26 EAN32442.1 - 5.2e-41 139.6 0.0 5.8e-41 139.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAN32442.1 - 0.016 15.5 0.2 0.035 14.4 0.1 1.6 2 0 0 2 2 2 0 RWD domain Coatomer_WDAD PF04053.14 EAN32443.1 - 2.9e-50 171.6 12.2 2.9e-50 171.6 12.2 2.6 3 1 0 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 EAN32443.1 - 4.2e-33 112.8 22.5 6.7e-08 33.1 0.2 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat COPI_C PF06957.11 EAN32443.1 - 9.1e-22 77.4 6.6 1.6e-21 76.6 6.6 1.3 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus ANAPC4_WD40 PF12894.7 EAN32443.1 - 0.011 16.0 0.1 3.2 8.1 0.0 4.3 3 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 EAN32443.1 - 0.21 11.8 1.5 2.2 8.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat AP2 PF00847.20 EAN32444.1 - 1.6e-07 31.4 4.3 0.00033 20.8 0.5 2.7 2 0 0 2 2 2 2 AP2 domain DUF3067 PF11267.8 EAN32445.1 - 0.043 14.4 0.4 4.1 8.1 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) XRN_N PF03159.18 EAN32446.1 - 1.1e-81 273.9 0.1 2.7e-80 269.3 0.0 2.9 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EAN32446.1 - 1.7e-55 188.8 10.3 8.8e-22 77.7 0.1 3.7 4 0 0 4 4 4 3 Xrn1 helical domain SH3_12 PF18129.1 EAN32446.1 - 8.4e-25 86.7 0.0 2.1e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D1 PF18332.1 EAN32446.1 - 0.00024 20.9 0.6 0.0034 17.2 0.1 2.9 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D1 domain MACPF PF01823.19 EAN32447.1 - 7.3e-47 160.2 2.9 7.3e-47 160.2 2.9 2.6 2 0 0 2 2 2 1 MAC/Perforin domain tRNA-synt_2d PF01409.20 EAN32448.1 - 4.1e-28 98.5 3.7 2.2e-13 50.2 1.8 4.4 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EAN32448.1 - 1.7e-19 70.0 0.3 6.7e-19 68.1 0.1 2.1 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 EAN32448.1 - 0.00011 21.4 0.1 0.37 9.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) Presenilin PF01080.17 EAN32449.1 - 8.2 5.1 11.2 13 4.4 11.2 1.3 1 0 0 1 1 1 0 Presenilin C2 PF00168.30 EAN32450.1 - 1.1e-10 41.8 0.1 3.1e-09 37.0 0.0 3.0 2 1 0 2 2 2 1 C2 domain DUF553 PF04473.12 EAN32450.1 - 0.048 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like domain DUF4597 PF15366.6 EAN32450.1 - 0.14 11.9 0.1 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) DHO_dh PF01180.21 EAN32452.1 - 3e-60 203.9 2.1 6.2e-51 173.3 0.0 2.0 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase AAA PF00004.29 EAN32453.1 - 1.2e-52 177.9 0.0 2.8e-38 131.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAN32453.1 - 3.5e-10 40.0 0.0 7.6e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAN32453.1 - 7.7e-10 39.4 1.4 0.0014 19.0 0.2 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EAN32453.1 - 8.6e-10 39.0 4.7 0.024 14.9 1.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 EAN32453.1 - 1.8e-09 37.3 0.0 3.6e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 EAN32453.1 - 1.7e-08 34.0 0.0 0.0021 17.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 EAN32453.1 - 2.1e-08 34.4 0.0 0.0042 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EAN32453.1 - 7.1e-08 32.7 0.0 2.8e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EAN32453.1 - 1.8e-07 31.1 0.3 0.0026 17.5 0.0 3.3 4 0 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 EAN32453.1 - 6.5e-07 29.5 0.1 0.19 11.6 0.0 4.1 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea TsaE PF02367.17 EAN32453.1 - 8.6e-07 29.0 0.1 0.065 13.2 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EAN32453.1 - 1.2e-06 29.1 0.0 0.006 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EAN32453.1 - 1.3e-06 27.9 0.1 0.0051 16.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EAN32453.1 - 5.8e-06 26.3 0.3 0.15 12.0 0.1 3.1 3 1 0 3 3 2 2 NACHT domain AAA_14 PF13173.6 EAN32453.1 - 2.5e-05 24.3 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EAN32453.1 - 2.6e-05 24.0 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 EAN32453.1 - 2.8e-05 23.7 0.1 0.0091 15.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EAN32453.1 - 3.1e-05 24.3 0.0 0.03 14.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 EAN32453.1 - 0.00013 21.2 0.2 0.74 9.0 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain AAA_24 PF13479.6 EAN32453.1 - 0.00015 21.6 0.0 0.032 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EAN32453.1 - 0.00077 19.2 0.0 0.43 10.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AFG1_ATPase PF03969.16 EAN32453.1 - 0.0011 17.9 0.0 0.63 8.9 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_25 PF13481.6 EAN32453.1 - 0.0013 18.4 2.4 0.33 10.5 0.0 3.2 3 1 1 4 4 3 1 AAA domain Parvo_NS1 PF01057.17 EAN32453.1 - 0.0014 17.8 0.0 0.036 13.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 TniB PF05621.11 EAN32453.1 - 0.0017 17.8 0.0 2 7.8 0.0 3.4 2 1 1 3 3 3 1 Bacterial TniB protein Rad17 PF03215.15 EAN32453.1 - 0.0038 17.2 0.1 0.21 11.5 0.0 2.9 2 1 1 3 3 3 1 Rad17 P-loop domain ATPase PF06745.13 EAN32453.1 - 0.0049 16.2 0.0 0.058 12.7 0.0 2.4 2 0 0 2 2 2 1 KaiC Cytidylate_kin PF02224.18 EAN32453.1 - 0.005 16.6 0.2 3.2 7.4 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase AAA_28 PF13521.6 EAN32453.1 - 0.0063 16.8 0.0 0.51 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAN32453.1 - 0.0073 16.0 0.1 0.75 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain DAP3 PF10236.9 EAN32453.1 - 0.0083 15.3 0.2 0.36 10.0 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 EAN32453.1 - 0.011 15.5 0.5 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EAN32453.1 - 0.014 15.9 0.1 3.1 8.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.16 EAN32453.1 - 0.016 14.7 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 EAN32453.1 - 0.019 14.7 0.2 0.44 10.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EAN32453.1 - 0.02 15.3 0.3 1.8 9.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 EAN32453.1 - 0.023 14.0 0.2 1.8 7.8 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_PrkA PF08298.11 EAN32453.1 - 0.03 13.2 0.0 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain DNA_pol3_delta2 PF13177.6 EAN32453.1 - 0.038 13.8 0.0 0.48 10.2 0.0 2.6 2 1 0 2 2 2 0 DNA polymerase III, delta subunit DUF2075 PF09848.9 EAN32453.1 - 0.044 13.0 0.2 0.42 9.8 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 EAN32453.1 - 0.045 12.9 0.1 7.5 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 EAN32453.1 - 0.053 13.9 0.0 0.55 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 EAN32453.1 - 0.094 12.8 0.0 22 5.2 0.0 2.5 2 0 0 2 2 2 0 Torsin CPT PF07931.12 EAN32453.1 - 0.2 11.5 0.1 2.4 8.0 0.0 2.4 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein CRM1_C PF08767.11 EAN32457.1 - 6.6e-11 42.0 0.3 8.4e-11 41.6 0.3 1.1 1 0 0 1 1 1 1 CRM1 C terminal TraE PF05309.11 EAN32457.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 TraE protein CRM1_C PF08767.11 EAN32458.1 - 2.2e-56 191.4 1.7 2.2e-56 191.4 1.7 3.1 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 EAN32458.1 - 6.9e-35 120.3 9.4 1.3e-34 119.4 1.6 3.7 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 EAN32458.1 - 3.6e-19 68.6 3.7 1.8e-18 66.4 0.1 3.4 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 EAN32458.1 - 4.6e-17 61.4 1.8 4.6e-17 61.4 1.8 2.9 3 0 0 3 3 3 1 CRM1 / Exportin repeat 2 IBN_N PF03810.19 EAN32458.1 - 2.6e-12 46.5 0.7 7.5e-12 45.0 0.3 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 EAN32458.1 - 3.6e-06 26.4 0.4 1.5e-05 24.4 0.4 2.2 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat DUF236 PF03057.14 EAN32458.1 - 0.0062 16.5 0.7 0.013 15.5 0.7 1.5 1 0 0 1 1 1 1 DUF236 repeat Sterile PF03015.19 EAN32458.1 - 0.017 15.3 1.7 3 8.1 0.1 3.3 2 0 0 2 2 2 0 Male sterility protein DUF3385 PF11865.8 EAN32458.1 - 0.021 14.7 0.8 0.18 11.7 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) Pkinase PF00069.25 EAN32459.1 - 2.3e-46 158.3 0.5 2.3e-46 158.3 0.5 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32459.1 - 1.1e-19 70.8 0.0 7.2e-19 68.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAN32459.1 - 0.014 14.2 0.0 0.027 13.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Apis_Csd PF11671.8 EAN32459.1 - 1.4 8.9 7.3 6.8 6.7 2.5 2.7 2 0 0 2 2 2 0 Complementary sex determiner protein ABC2_membrane_3 PF12698.7 EAN32459.1 - 1.9 7.5 8.3 0.15 11.2 2.7 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein TYW3 PF02676.14 EAN32460.1 - 8.8e-39 133.1 0.3 1.8e-38 132.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase TYW3 Met_10 PF02475.16 EAN32460.1 - 3.4e-20 72.7 4.1 2.2e-11 43.9 0.0 2.8 3 0 0 3 3 3 2 Met-10+ like-protein Kelch_4 PF13418.6 EAN32460.1 - 6.1e-12 45.4 1.6 0.0055 16.7 0.0 6.1 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EAN32460.1 - 9.3e-07 28.7 12.8 0.94 9.5 0.5 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 EAN32460.1 - 4.4e-05 23.6 2.5 0.67 10.3 0.0 5.7 6 0 0 6 6 6 1 Kelch motif MTS PF05175.14 EAN32460.1 - 5.9e-05 22.7 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Kelch_1 PF01344.25 EAN32460.1 - 0.00021 20.8 5.7 0.93 9.1 0.0 5.3 6 0 0 6 6 6 2 Kelch motif PrmA PF06325.13 EAN32460.1 - 0.0021 17.5 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EAN32460.1 - 0.0023 18.6 0.0 0.0061 17.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAN32460.1 - 0.0023 17.7 0.0 0.0084 15.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Kelch_2 PF07646.15 EAN32460.1 - 0.0065 16.4 2.7 22 5.2 0.0 4.7 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.6 EAN32460.1 - 0.0088 16.3 0.1 9.1 6.7 0.0 4.4 5 0 0 5 5 5 1 Galactose oxidase, central domain PHF5 PF03660.14 EAN32461.1 - 7.2e-49 164.3 15.3 8.7e-49 164.1 15.3 1.0 1 0 0 1 1 1 1 PHF5-like protein GTP_EFTU PF00009.27 EAN32462.1 - 2.5e-32 112.0 0.0 2.5e-32 112.0 0.0 3.3 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EAN32462.1 - 4.9e-17 62.0 2.7 1.2e-16 60.7 0.3 2.5 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 EAN32462.1 - 2.3e-12 46.7 0.0 5.8e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 EAN32462.1 - 1.3e-10 41.5 1.6 5.6e-07 29.9 0.3 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAN32462.1 - 7.2e-07 29.3 0.0 1.9e-05 24.7 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EAN32462.1 - 5.9e-05 23.3 0.0 0.00022 21.4 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EAN32462.1 - 0.0018 18.1 0.0 0.015 15.1 0.0 2.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EAN32462.1 - 1.5 9.1 6.5 2.3 8.5 0.0 3.9 3 2 1 4 4 4 0 AAA domain zf-RING_2 PF13639.6 EAN32463.1 - 1.3e-08 35.0 1.5 1.3e-08 35.0 1.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EAN32463.1 - 1.1e-06 28.8 1.9 3.7e-06 27.1 1.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EAN32463.1 - 1.2e-05 25.0 0.6 1.2e-05 25.0 0.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAN32463.1 - 5.1e-05 23.1 0.9 0.00012 21.8 0.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EAN32463.1 - 0.00018 21.3 2.1 0.00018 21.3 2.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EAN32463.1 - 0.00083 18.9 0.4 0.0022 17.6 0.4 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EAN32463.1 - 0.0026 17.8 0.8 0.0068 16.5 0.8 1.7 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.25 EAN32463.1 - 0.003 17.4 5.6 0.011 15.6 5.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAN32463.1 - 0.004 17.1 4.4 0.0075 16.2 3.6 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EAN32463.1 - 0.013 15.3 0.1 0.013 15.3 0.1 3.5 4 0 0 4 4 4 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EAN32463.1 - 0.02 14.9 2.0 0.025 14.6 0.6 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EAN32463.1 - 0.05 13.6 3.3 0.06 13.4 1.3 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 EAN32463.1 - 0.13 12.1 0.6 0.31 10.8 0.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 EAN32463.1 - 0.96 9.8 3.3 2.1 8.7 3.3 1.6 1 0 0 1 1 1 0 RING-like domain CTU2 PF10288.9 EAN32463.1 - 1.9 8.7 9.1 1.6 9.0 2.4 2.6 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Nop25 PF09805.9 EAN32463.1 - 6.5 7.2 9.3 7.5 7.0 1.0 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) EXS PF03124.14 EAN32464.1 - 2.8e-51 174.8 21.5 5e-51 174.0 21.5 1.4 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EAN32464.1 - 8.7e-13 48.9 19.0 1.1e-10 42.0 19.0 2.1 1 1 0 1 1 1 1 SPX domain Polysacc_synt PF01943.17 EAN32464.1 - 0.0037 16.7 0.6 0.0037 16.7 0.6 2.8 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Phage_sheath_1C PF17482.2 EAN32464.1 - 0.099 12.6 0.2 0.31 11.0 0.2 1.9 1 0 0 1 1 1 0 Phage tail sheath C-terminal domain DUF5592 PF17332.2 EAN32464.1 - 1.3 9.6 10.5 0.097 13.2 4.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5592) WD40 PF00400.32 EAN32465.1 - 0.00069 20.4 11.7 0.35 11.8 1.3 5.3 5 1 1 6 6 6 2 WD domain, G-beta repeat DUF4627 PF15425.6 EAN32465.1 - 0.092 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4627) GlcNAc-1_reg PF18440.1 EAN32466.1 - 0.041 14.1 0.1 0.13 12.5 0.1 1.8 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain Fzo_mitofusin PF04799.13 EAN32467.1 - 0.54 9.8 7.1 0.51 9.9 4.8 2.1 1 1 1 2 2 2 0 fzo-like conserved region GYF PF02213.16 EAN32468.1 - 2.3e-11 43.2 7.2 7.2e-11 41.6 7.2 1.9 1 0 0 1 1 1 1 GYF domain ribosomal_L24 PF17136.4 EAN32469.1 - 3.2e-12 46.6 0.1 6.7e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 EAN32469.1 - 2.5e-07 30.4 1.4 4.8e-07 29.5 1.4 1.5 1 0 0 1 1 1 1 KOW motif Gag_p10 PF02337.17 EAN32469.1 - 0.0094 15.9 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral GAG p10 protein Cyclin_N PF00134.23 EAN32471.1 - 0.00028 20.6 0.3 0.00049 19.8 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 EAN32472.1 - 1.8e-58 198.0 0.0 3.3e-41 141.4 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32472.1 - 1.8e-33 116.0 0.2 6.4e-26 91.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAN32472.1 - 0.00088 18.7 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EAN32472.1 - 0.048 13.0 0.1 0.087 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAN32472.1 - 0.056 12.4 0.4 0.096 11.6 0.4 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EAN32472.1 - 0.059 12.4 0.2 0.086 11.9 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glutaredoxin PF00462.24 EAN32477.1 - 4.2e-17 62.1 0.0 1.1e-16 60.7 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin TnpW PF14202.6 EAN32477.1 - 0.11 12.3 1.0 0.22 11.4 1.0 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpW GST_N_3 PF13417.6 EAN32477.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Methyltransf_23 PF13489.6 EAN32478.1 - 1.6e-22 80.1 0.0 2e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAN32478.1 - 1.6e-16 60.7 0.0 3.7e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAN32478.1 - 8.2e-16 58.2 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAN32478.1 - 3.1e-15 56.7 0.0 1.6e-14 54.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAN32478.1 - 2.6e-13 50.6 0.0 5.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAN32478.1 - 8.5e-10 38.4 0.1 2.9e-09 36.6 0.1 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EAN32478.1 - 1.6e-06 27.7 0.0 3e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 EAN32478.1 - 7.7e-06 25.4 0.2 0.00021 20.8 0.2 2.1 1 1 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 EAN32478.1 - 0.00016 21.1 0.0 0.00031 20.1 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 EAN32478.1 - 0.00017 21.2 0.3 0.00063 19.3 0.2 1.8 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 EAN32478.1 - 0.0002 21.4 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EAN32478.1 - 0.00045 19.9 0.0 0.0097 15.5 0.0 2.1 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 EAN32478.1 - 0.00068 18.6 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EAN32478.1 - 0.0029 17.2 0.0 0.0055 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 EAN32478.1 - 0.0045 16.1 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TPMT PF05724.11 EAN32478.1 - 0.0059 16.3 0.0 0.0087 15.7 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 EAN32478.1 - 0.0071 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Spermine_synth PF01564.17 EAN32478.1 - 0.0074 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_15 PF09445.10 EAN32478.1 - 0.019 14.6 0.3 0.049 13.2 0.2 1.8 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_PK PF05891.12 EAN32478.1 - 0.021 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MetW PF07021.12 EAN32478.1 - 0.12 11.9 0.2 0.29 10.7 0.2 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW PDCD2_C PF04194.13 EAN32479.1 - 7.3e-16 58.7 0.0 6.6e-14 52.4 0.0 2.3 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain YdjO PF14169.6 EAN32479.1 - 0.19 11.5 3.9 7.2 6.4 0.1 2.8 3 0 0 3 3 3 0 Cold-inducible protein YdjO Cwf_Cwc_15 PF04889.12 EAN32479.1 - 3.2 7.4 7.5 4.3 7.0 7.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Topoisom_I PF01028.20 EAN32480.1 - 3.4e-106 353.7 9.7 3.4e-106 353.7 9.7 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EAN32480.1 - 5.9e-74 248.2 6.2 5.9e-74 248.2 6.2 3.2 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EAN32480.1 - 1.8e-32 111.0 2.0 9.3e-32 108.8 2.0 2.4 1 0 0 1 1 1 1 C-terminal topoisomerase domain TC1 PF15063.6 EAN32480.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Thyroid cancer protein 1 SKA2 PF16740.5 EAN32480.1 - 0.58 10.0 7.7 0.45 10.3 1.7 3.2 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Bromodomain PF00439.25 EAN32481.1 - 8.4e-15 54.6 0.5 4.9e-14 52.2 0.1 2.5 2 0 0 2 2 2 1 Bromodomain PIP5K PF01504.18 EAN32482.1 - 2.3e-74 250.1 0.6 2.3e-74 250.1 0.6 2.3 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_1 PF00036.32 EAN32482.1 - 0.0015 17.9 1.6 0.012 15.2 0.4 3.0 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EAN32482.1 - 0.0018 18.7 0.1 0.45 11.0 0.0 3.2 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EAN32482.1 - 0.005 16.7 0.2 0.46 10.5 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain Baculo_PEP_C PF04513.12 EAN32482.1 - 0.0053 16.8 2.9 0.0053 16.8 2.9 1.9 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus NADPH_Ox PF08414.10 EAN32482.1 - 0.032 14.6 0.0 0.95 9.8 0.0 3.0 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase EF-hand_8 PF13833.6 EAN32482.1 - 0.11 12.4 0.8 0.89 9.4 0.8 2.6 1 1 0 1 1 1 0 EF-hand domain pair JAB PF01398.21 EAN32483.1 - 2.2e-31 108.3 0.0 4.9e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EAN32483.1 - 1.8e-09 38.0 0.3 3.7e-09 37.0 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EAN32483.1 - 2.9e-09 36.7 0.0 5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TFIIB PF00382.19 EAN32484.1 - 3.7e-15 55.7 0.1 2.7e-08 33.7 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EAN32484.1 - 1.4e-08 34.1 0.6 2.5e-08 33.3 0.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding CYTL1 PF15153.6 EAN32484.1 - 0.011 15.7 0.7 0.094 12.7 0.3 2.3 1 1 1 2 2 2 0 Cytokine-like protein 1 HTH_24 PF13412.6 EAN32484.1 - 0.025 14.2 0.1 0.18 11.4 0.0 2.5 3 1 1 4 4 4 0 Winged helix-turn-helix DNA-binding Ribosomal_S27e PF01667.17 EAN32484.1 - 0.098 12.4 1.2 0.22 11.2 1.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 HTH_36 PF13730.6 EAN32484.1 - 0.22 11.5 3.3 7.1 6.7 0.0 3.7 5 0 0 5 5 5 0 Helix-turn-helix domain zf-RING_9 PF13901.6 EAN32484.1 - 0.23 11.4 3.3 18 5.2 0.2 2.9 2 1 1 3 3 3 0 Putative zinc-RING and/or ribbon AAA_18 PF13238.6 EAN32485.1 - 4.8e-19 69.2 0.1 1.6e-18 67.5 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAN32485.1 - 1.9e-06 28.4 0.0 2.5e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EAN32485.1 - 6e-06 26.5 0.0 0.00085 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EAN32485.1 - 1.9e-05 25.1 0.0 6.5e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAN32485.1 - 0.00011 22.5 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EAN32485.1 - 0.00022 20.7 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_17 PF13207.6 EAN32485.1 - 0.00055 20.4 0.1 0.0033 17.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAN32485.1 - 0.0012 18.6 0.2 0.0031 17.3 0.0 1.7 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase Thymidylate_kin PF02223.17 EAN32485.1 - 0.0019 17.9 0.1 0.52 10.0 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase MMR_HSR1 PF01926.23 EAN32485.1 - 0.0023 18.0 0.0 0.0032 17.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 EAN32485.1 - 0.0025 17.0 0.1 0.0037 16.5 0.1 1.5 1 1 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.14 EAN32485.1 - 0.0027 17.7 0.0 0.0039 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Cas_DxTHG PF09455.10 EAN32485.1 - 0.0032 17.1 0.4 0.0035 17.0 0.4 1.2 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family RNA_helicase PF00910.22 EAN32485.1 - 0.0057 17.0 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 EAN32485.1 - 0.0065 17.0 0.0 0.011 16.2 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 EAN32485.1 - 0.0066 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 EAN32485.1 - 0.0068 16.3 0.1 0.042 13.8 0.0 2.2 3 0 0 3 3 2 1 NTPase CNOT1_TTP_bind PF16417.5 EAN32485.1 - 0.0069 15.6 3.9 0.65 9.1 0.0 2.1 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF815 PF05673.13 EAN32485.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 EAN32485.1 - 0.016 15.0 0.0 0.052 13.3 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AIG1 PF04548.16 EAN32485.1 - 0.017 14.5 0.1 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 AIG1 family AAA_28 PF13521.6 EAN32485.1 - 0.017 15.4 1.2 0.055 13.7 1.2 2.0 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EAN32485.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 EAN32485.1 - 0.028 14.5 0.2 0.11 12.5 0.2 2.1 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EAN32485.1 - 0.033 13.5 0.1 0.086 12.2 0.1 1.7 1 1 1 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EAN32485.1 - 0.036 13.3 0.0 0.084 12.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ADK PF00406.22 EAN32485.1 - 0.047 13.8 2.2 0.85 9.7 0.1 2.9 1 1 1 2 2 2 0 Adenylate kinase Mg_chelatase PF01078.21 EAN32485.1 - 0.058 12.8 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EAN32485.1 - 0.083 12.6 0.1 0.14 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EAN32485.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 EAN32485.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 EAN32485.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MCM PF00493.23 EAN32485.1 - 0.14 11.2 0.0 0.34 10.0 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 EAN32485.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 EAN32485.1 - 0.21 10.5 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Methyltr_RsmB-F PF01189.17 EAN32486.1 - 1.4e-28 99.9 0.0 2.5e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 EAN32486.1 - 3.9e-09 36.5 0.0 6.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAN32486.1 - 3.7e-08 33.0 0.0 6.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltr_RsmF_N PF17125.5 EAN32486.1 - 4.5e-07 30.3 0.0 1.6e-06 28.5 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_25 PF13649.6 EAN32486.1 - 1.4e-06 28.9 0.0 3.9e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAN32486.1 - 0.00014 21.5 0.0 0.00093 18.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 EAN32486.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EAN32486.1 - 0.021 15.6 0.0 0.04 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 EAN32486.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RNA_POL_M_15KD PF02150.16 EAN32487.1 - 1.8e-07 30.9 5.7 1.9e-07 30.8 2.6 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 EAN32487.1 - 2.3e-06 27.3 1.1 2.3e-06 27.3 1.1 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 EAN32487.1 - 0.012 15.6 2.4 0.16 12.0 1.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-ACC PF17848.1 EAN32487.1 - 0.2 11.8 0.4 0.2 11.8 0.4 3.2 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain HscB_4_cys PF18256.1 EAN32487.1 - 0.37 10.7 5.3 27 4.7 0.0 3.4 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif zinc_ribbon_10 PF10058.9 EAN32487.1 - 1.3 8.8 0.0 1.3 8.8 0.0 3.3 3 1 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein GFA PF04828.14 EAN32487.1 - 2.8 8.3 9.5 9.3 6.7 0.3 3.7 2 2 1 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme Evr1_Alr PF04777.13 EAN32488.1 - 1.9e-19 70.0 0.0 2.1e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family FAINT PF04385.15 EAN32490.1 - 0.00026 21.0 0.2 0.00026 21.0 0.2 1.4 2 0 0 2 2 2 1 Domain of unknown function, DUF529 Prefoldin_2 PF01920.20 EAN32491.1 - 1.9e-05 24.6 5.7 1.9e-05 24.6 5.7 1.6 2 0 0 2 2 1 1 Prefoldin subunit BLOC1_2 PF10046.9 EAN32491.1 - 0.0018 18.6 6.0 0.11 12.7 0.7 2.4 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL PF10241.9 EAN32491.1 - 0.024 14.9 5.6 0.92 9.8 0.8 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 EAN32491.1 - 0.045 13.8 3.5 2.8 8.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 EAN32491.1 - 0.051 13.7 1.6 5.8 7.0 0.2 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF745 PF05335.13 EAN32491.1 - 0.12 12.1 0.4 0.23 11.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) FadA PF09403.10 EAN32491.1 - 0.12 12.9 4.5 0.13 12.7 2.6 2.0 2 1 0 2 2 2 0 Adhesion protein FadA COG5 PF10392.9 EAN32491.1 - 0.13 12.4 5.1 3.2 7.9 0.1 2.8 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF4795 PF16043.5 EAN32491.1 - 0.14 11.8 4.1 0.87 9.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) XhlA PF10779.9 EAN32491.1 - 0.17 12.1 8.2 0.55 10.5 1.7 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Syntaxin-6_N PF09177.11 EAN32491.1 - 0.18 12.4 5.9 3 8.4 4.3 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TMPIT PF07851.13 EAN32491.1 - 0.23 10.7 4.1 0.44 9.7 4.2 1.4 1 1 0 1 1 1 0 TMPIT-like protein DUF2508 PF10704.9 EAN32491.1 - 0.46 10.7 9.1 7.8 6.7 1.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) CC2-LZ PF16516.5 EAN32491.1 - 0.89 10.0 7.4 8.9 6.8 0.5 2.7 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Fzo_mitofusin PF04799.13 EAN32491.1 - 2.2 7.8 5.9 3.7 7.1 1.1 2.3 1 1 1 2 2 2 0 fzo-like conserved region SAPIS-gp6 PF16722.5 EAN32491.1 - 2.9 8.3 8.8 0.68 10.4 0.7 3.1 3 1 0 3 3 3 0 Pathogenicity island protein gp6 in Staphylococcus FlaC_arch PF05377.11 EAN32491.1 - 3.8 8.0 8.2 2.6 8.5 0.2 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Vac_Fusion PF02346.16 EAN32491.1 - 3.9 7.2 6.5 12 5.6 0.3 3.2 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF16 PF01519.16 EAN32491.1 - 5.3 7.6 9.1 44 4.6 9.1 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 FAINT PF04385.15 EAN32492.1 - 3.3e-11 43.1 0.6 1.4e-06 28.2 1.3 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32493.1 - 9.1e-08 32.1 0.1 2.7e-05 24.1 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 Ig_2 PF13895.6 EAN32493.1 - 0.016 15.5 0.1 0.84 10.0 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain FAINT PF04385.15 EAN32494.1 - 1.1e-08 34.9 4.7 0.00011 22.2 0.4 2.8 2 1 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32495.1 - 6.5e-12 45.4 9.8 2.6e-08 33.8 0.3 3.1 3 0 0 3 3 3 2 Domain of unknown function, DUF529 Atg31 PF09795.9 EAN32495.1 - 0.0036 17.3 3.4 0.0046 17.0 0.7 2.4 2 0 0 2 2 2 1 Autophagy-related protein 31 FAINT PF04385.15 EAN32496.1 - 2.9e-11 43.2 0.2 3.9e-06 26.8 0.2 2.7 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32497.1 - 4e-10 39.6 5.2 9.5e-05 22.4 0.3 2.9 2 1 1 3 3 3 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32498.1 - 2.3e-12 46.8 0.7 2.3e-12 46.8 0.7 2.8 2 1 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN32499.1 - 0.00044 20.2 3.2 0.0065 16.5 0.1 3.9 4 1 0 4 4 4 2 Domain of unknown function, DUF529 Lectin_N PF03954.14 EAN32499.1 - 0.015 15.0 0.9 0.015 15.0 0.9 4.3 4 0 0 4 4 4 0 Hepatic lectin, N-terminal domain GIT_CC PF16559.5 EAN32499.1 - 0.13 12.1 21.1 0.059 13.3 4.0 4.0 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.12 EAN32499.1 - 5.5 7.7 24.1 12 6.6 0.3 5.8 4 1 1 5 5 5 0 SlyX G10 PF01125.17 EAN32500.1 - 3.9e-65 218.1 3.6 4.4e-65 217.9 3.6 1.0 1 0 0 1 1 1 1 G10 protein Peptidase_M16 PF00675.20 EAN32501.1 - 1.4e-27 96.5 1.0 2.6e-27 95.7 0.6 1.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EAN32501.1 - 1e-24 87.6 0.0 4.5e-24 85.5 0.0 2.2 3 0 0 3 3 3 1 Peptidase M16 inactive domain Ssl1 PF04056.14 EAN32501.1 - 0.041 13.7 1.1 0.14 12.0 0.0 2.2 3 0 0 3 3 3 0 Ssl1-like DnaJ-X PF14308.6 EAN32504.1 - 5.2e-46 156.7 0.0 8.5e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EAN32504.1 - 5.1e-21 74.6 0.9 1.3e-20 73.3 0.9 1.7 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.11 EAN32504.1 - 5.5e-05 23.4 0.0 0.00017 21.8 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Ribosomal_S14 PF00253.21 EAN32505.1 - 1.1e-12 47.5 3.2 1.3e-12 47.3 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e CAP PF00188.26 EAN32506.1 - 4.3e-05 24.3 0.1 5.1e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Antimicrobial12 PF08107.11 EAN32506.1 - 0.49 10.2 2.9 0.84 9.4 2.9 1.4 1 0 0 1 1 1 0 Pleurocidin family CRT-like PF08627.10 EAN32507.1 - 2.2e-44 151.8 29.7 2.8e-44 151.4 29.7 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like AP2 PF00847.20 EAN32509.1 - 8.3e-12 45.2 1.6 1.3e-11 44.5 1.6 1.3 1 0 0 1 1 1 1 AP2 domain WD40 PF00400.32 EAN32511.1 - 9.3e-07 29.5 0.7 3.6e-05 24.4 0.0 3.0 3 1 0 3 3 3 1 WD domain, G-beta repeat WD40_like PF17005.5 EAN32511.1 - 0.0037 16.6 0.0 0.0054 16.1 0.0 1.3 1 1 0 1 1 1 1 WD40-like domain ANAPC4_WD40 PF12894.7 EAN32511.1 - 0.0038 17.5 0.0 0.0078 16.5 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain MadL PF03817.13 EAN32512.1 - 0.084 12.9 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 Malonate transporter MadL subunit Syntaxin PF00804.25 EAN32513.1 - 5.4e-19 68.7 12.0 6.8e-19 68.3 12.0 1.1 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EAN32513.1 - 4.1e-09 36.3 0.2 1.7e-08 34.3 0.2 2.1 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 EAN32513.1 - 0.00011 22.5 5.7 0.00011 22.5 5.7 2.5 2 0 0 2 2 2 1 Syntaxin-like protein Mod_r PF07200.13 EAN32513.1 - 0.014 15.5 9.9 0.081 13.0 2.7 2.9 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein zf-C2HE PF16278.5 EAN32513.1 - 0.016 15.7 0.0 0.055 13.9 0.0 1.9 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger MCM_N PF14551.6 EAN32513.1 - 0.039 14.5 0.4 0.12 13.0 0.1 1.9 2 0 0 2 2 2 0 MCM N-terminal domain RNA_pol_Rpb1_5 PF04998.17 EAN32513.1 - 0.57 9.6 8.4 0.55 9.6 6.9 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Plk4_PB2 PF18409.1 EAN32513.1 - 1 10.1 8.5 2.2 9.0 1.5 3.0 1 1 2 3 3 3 0 Polo-like Kinase 4 Polo Box 2 IBN_N PF03810.19 EAN32514.1 - 2.5e-08 33.7 0.0 1.6e-07 31.2 0.0 2.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF4806 PF16064.5 EAN32514.1 - 0.054 13.8 1.3 5.3 7.4 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) Cnd1 PF12717.7 EAN32514.1 - 0.1 12.6 2.8 0.35 10.9 0.5 3.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF3487 PF11990.8 EAN32515.1 - 0.17 11.8 1.9 1.4 8.8 0.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) TENA_THI-4 PF03070.16 EAN32516.1 - 0.0059 16.4 0.0 6.8 6.4 0.0 3.2 3 0 0 3 3 3 2 TENA/THI-4/PQQC family GCV_H PF01597.19 EAN32517.1 - 2.9e-07 30.4 0.0 4.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein Ribosomal_L37e PF01907.19 EAN32518.1 - 2.7e-23 81.9 9.8 4.4e-23 81.2 9.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DUF3823 PF12866.7 EAN32519.1 - 0.12 12.7 0.2 0.27 11.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) N-terminal domain RNA_pol_N PF01194.17 EAN32520.1 - 3.2e-32 110.6 0.9 4e-32 110.3 0.9 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Nkap_C PF06047.11 EAN32521.1 - 1.8e-41 140.3 5.9 1.8e-41 140.3 5.9 1.7 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain TMEM237 PF15383.6 EAN32521.1 - 0.69 9.0 4.3 3.2 6.8 1.3 2.3 2 0 0 2 2 2 0 Transmembrane protein 237 FAST_1 PF06743.15 EAN32523.1 - 0.018 15.0 0.7 2 8.4 0.0 3.6 3 1 1 4 4 4 0 FAST kinase-like protein, subdomain 1 Pkinase PF00069.25 EAN32524.1 - 6.8e-08 32.2 0.1 8.6e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAN32524.1 - 3.5e-07 29.8 0.1 0.00017 21.0 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAN32524.1 - 3.6e-07 30.4 0.0 1.9e-05 24.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EAN32524.1 - 2.3e-06 27.1 0.1 2.8e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EAN32524.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 RIO1 family WaaY PF06176.11 EAN32524.1 - 0.0076 15.9 0.0 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) EcKinase PF02958.20 EAN32524.1 - 0.034 13.4 0.3 0.044 13.1 0.3 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 EAN32524.1 - 0.048 13.2 0.1 0.95 9.0 0.1 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase SCO1-SenC PF02630.14 EAN32525.1 - 1.6e-45 154.3 0.0 2.1e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EAN32525.1 - 9.4e-06 25.6 0.2 2.2e-05 24.4 0.2 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EAN32525.1 - 6.3e-05 23.2 0.1 0.00015 22.0 0.1 1.8 2 1 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 EAN32525.1 - 0.0013 18.5 0.2 0.01 15.6 0.2 2.0 1 1 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 EAN32525.1 - 0.042 14.3 0.2 0.076 13.5 0.2 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Npun_R1517 PF18068.1 EAN32525.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Npun R1517 HSP70 PF00012.20 EAN32526.1 - 8.2e-66 222.4 0.0 8.2e-66 222.4 0.0 3.9 3 1 1 4 4 4 2 Hsp70 protein DUF4768 PF15989.5 EAN32526.1 - 0.041 13.8 1.3 7.5 6.6 0.1 3.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4768) Baculo_PEP_C PF04513.12 EAN32526.1 - 0.14 12.2 6.6 0.1 12.6 1.2 2.7 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BUD22 PF09073.10 EAN32526.1 - 7.6 5.7 24.4 0.7 9.2 12.5 2.2 2 0 0 2 2 2 0 BUD22 HSP90 PF00183.18 EAN32527.1 - 4e-228 758.5 31.4 5.2e-228 758.1 31.4 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EAN32527.1 - 3.4e-14 53.3 0.0 7.1e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EAN32527.1 - 8.7e-11 41.8 0.1 2.7e-10 40.2 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4136 PF13590.6 EAN32527.1 - 0.023 15.3 0.3 0.11 13.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4136) LOH1CR12 PF10158.9 EAN32527.1 - 0.037 14.1 0.1 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 Tumour suppressor protein RNA_polI_A34 PF08208.11 EAN32527.1 - 0.73 9.9 16.9 1.7 8.7 16.9 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Arf PF00025.21 EAN32528.1 - 2.2e-73 245.4 0.0 2.6e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAN32528.1 - 8.4e-15 55.0 0.0 1.1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAN32528.1 - 7.2e-13 48.5 0.0 8.1e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EAN32528.1 - 9.3e-13 48.1 0.2 2.9e-07 30.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EAN32528.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAN32528.1 - 8.5e-10 38.4 0.0 1.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAN32528.1 - 0.00012 22.1 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EAN32528.1 - 0.0082 15.5 0.1 0.014 14.7 0.1 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Paf67 PF10255.9 EAN32530.1 - 2.2e-98 329.9 13.1 1e-73 248.7 9.0 2.1 2 0 0 2 2 2 2 RNA polymerase I-associated factor PAF67 NOG1_N PF17835.1 EAN32531.1 - 1.5e-46 158.3 0.6 1.5e-46 158.3 0.6 2.4 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 EAN32531.1 - 5.6e-25 86.9 0.1 3.4e-24 84.4 0.2 2.2 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 EAN32531.1 - 1.6e-23 82.4 0.2 3.5e-23 81.3 0.2 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 EAN32531.1 - 3.3e-16 59.4 0.0 1.3e-15 57.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAN32531.1 - 2.9e-09 36.6 0.1 1.4e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.6 EAN32531.1 - 0.048 14.2 0.0 0.58 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain LRR_4 PF12799.7 EAN32532.1 - 0.00073 19.9 6.2 0.015 15.8 4.1 2.8 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAN32532.1 - 0.0068 16.1 2.5 0.028 14.2 2.5 2.1 1 1 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 EAN32532.1 - 0.18 12.0 6.7 22 5.4 0.5 4.2 3 1 0 3 3 3 0 Leucine Rich repeat KASH_CCD PF14662.6 EAN32533.1 - 0.074 12.9 0.4 0.074 12.9 0.4 4.0 3 1 0 3 3 2 0 Coiled-coil region of CCDC155 or KASH ERM PF00769.19 EAN32533.1 - 0.091 12.6 29.2 0.055 13.3 17.8 2.7 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.11 EAN32533.1 - 0.091 11.6 32.3 0.21 10.4 17.8 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF4795 PF16043.5 EAN32533.1 - 0.14 11.8 19.6 0.037 13.6 7.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) DUF1284 PF06935.11 EAN32533.1 - 0.26 11.7 0.1 0.26 11.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1284) UPF0242 PF06785.11 EAN32533.1 - 0.27 11.3 28.7 2 8.4 12.7 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Methyltransf_31 PF13847.6 EAN32533.1 - 0.4 10.5 4.5 0.29 10.9 0.3 2.5 2 0 0 2 2 2 0 Methyltransferase domain CREPT PF16566.5 EAN32533.1 - 0.97 9.6 25.9 0.039 14.1 10.8 3.5 3 1 1 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 EAN32533.1 - 2.3 8.3 12.8 6 6.9 9.7 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus VPS11_C PF12451.8 EAN32533.1 - 3.6 7.9 6.7 2.2 8.6 2.2 3.2 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal FadA PF09403.10 EAN32533.1 - 4.4 7.8 29.7 2.7 8.5 10.9 3.9 3 1 0 3 3 3 0 Adhesion protein FadA Apolipoprotein PF01442.18 EAN32533.1 - 5.5 6.8 20.3 0.1 12.5 10.2 2.7 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain HMMR_N PF15905.5 EAN32533.1 - 8.9 5.7 35.4 0.09 12.2 18.4 3.2 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal GNAT_acetyltr_2 PF13718.6 EAN32534.1 - 8.1e-84 280.5 0.1 6.1e-83 277.7 0.0 2.1 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 EAN32534.1 - 7.2e-49 166.0 0.0 1.6e-48 164.9 0.0 1.6 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 EAN32534.1 - 1.9e-36 125.9 0.2 7.1e-36 124.1 0.0 2.0 2 0 0 2 2 2 1 Possible tRNA binding domain DUF1726 PF08351.11 EAN32534.1 - 1.5e-31 108.2 0.0 3.9e-31 106.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Recep_L_domain PF01030.24 EAN32535.1 - 0.0041 17.2 0.2 0.0048 17.0 0.2 1.1 1 0 0 1 1 1 1 Receptor L domain DUF4325 PF14213.6 EAN32535.1 - 0.12 12.0 1.3 0.31 10.8 1.3 1.7 1 1 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) ATP-synt_DE_N PF02823.16 EAN32536.1 - 7.3e-13 48.2 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF1456 PF07308.13 EAN32537.1 - 0.0039 17.5 0.6 0.2 12.0 0.3 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1456) Nodulin PF02451.15 EAN32539.1 - 0.021 14.3 0.1 0.023 14.2 0.1 1.0 1 0 0 1 1 1 0 Nodulin M16C_assoc PF08367.11 EAN32540.1 - 3.3e-26 91.9 3.9 7.5e-26 90.8 3.9 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EAN32540.1 - 3.4e-15 56.5 0.6 3.4e-15 56.5 0.6 4.6 5 1 0 5 5 5 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EAN32540.1 - 3.3e-05 23.9 0.5 3.3e-05 23.9 0.5 3.6 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) TBCA PF02970.16 EAN32540.1 - 0.011 16.1 3.1 0.013 15.9 0.1 2.7 2 0 0 2 2 2 0 Tubulin binding cofactor A DUF5357 PF17310.2 EAN32540.1 - 0.14 10.7 0.9 7.3 5.0 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5357) Ion_trans_2 PF07885.16 EAN32542.1 - 0.00043 20.2 0.4 0.00043 20.2 0.4 3.5 4 1 0 4 4 4 1 Ion channel BK_channel_a PF03493.18 EAN32542.1 - 0.027 14.7 0.1 0.059 13.6 0.1 1.6 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit Peptidase_A24 PF01478.18 EAN32542.1 - 0.08 13.4 0.9 0.15 12.4 0.9 1.4 1 0 0 1 1 1 0 Type IV leader peptidase family ArAE_1 PF06081.11 EAN32542.1 - 1.5 8.9 9.8 0.44 10.7 5.5 2.0 2 0 0 2 2 2 0 Aromatic acid exporter family member 1 M16C_assoc PF08367.11 EAN32543.1 - 2.4e-39 135.0 6.7 5.8e-39 133.7 6.7 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EAN32543.1 - 8.4e-22 78.1 4.9 2.6e-17 63.4 0.3 4.2 4 1 0 4 4 4 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EAN32543.1 - 5.6e-08 32.9 0.1 8.3e-05 22.6 0.0 2.9 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) zf-MIZ PF02891.20 EAN32544.1 - 1.1e-19 69.9 1.6 2.9e-19 68.5 1.6 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EAN32544.1 - 0.0008 19.2 1.1 0.0028 17.4 1.1 2.0 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PINIT PF14324.6 EAN32544.1 - 0.004 17.5 0.7 0.012 16.0 0.7 1.8 1 0 0 1 1 1 1 PINIT domain PHD PF00628.29 EAN32544.1 - 0.11 12.4 16.3 0.2 11.6 7.4 2.8 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 EAN32544.1 - 3 8.0 12.2 0.41 10.8 1.6 3.3 3 1 0 3 3 3 0 PHD-finger RRM_1 PF00076.22 EAN32547.1 - 4.3e-15 55.3 0.0 7.3e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF900 PF05990.12 EAN32549.1 - 3.6e-12 46.3 0.0 1.5e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) DUF2207 PF09972.9 EAN32550.1 - 0.098 11.4 1.2 0.16 10.7 1.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3800 PF12686.7 EAN32551.1 - 0.11 13.2 0.8 6.6 7.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3800) IGPS PF00218.21 EAN32552.1 - 3.9e-19 68.8 0.0 8e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase ThiG PF05690.14 EAN32552.1 - 0.093 12.0 0.7 0.17 11.2 0.7 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EAN32552.1 - 0.27 10.2 1.1 0.48 9.4 0.2 1.9 2 1 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain WD40 PF00400.32 EAN32553.1 - 8.1e-10 39.1 7.8 5.5e-05 23.9 0.5 5.0 5 1 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 EAN32553.1 - 3.7e-05 22.6 0.5 0.00056 18.7 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PUL PF08324.11 EAN32554.1 - 7.4e-09 35.2 2.0 8.1e-09 35.1 1.9 1.3 1 1 0 1 1 1 1 PUL domain Ribosomal_L9_N PF01281.19 EAN32555.1 - 2.5e-13 49.3 0.0 5.1e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DUF2439 PF10382.9 EAN32556.1 - 0.00018 21.7 0.0 0.00047 20.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) FAINT PF04385.15 EAN32557.1 - 3.9e-10 39.7 50.6 3.5e-05 23.8 7.3 6.5 7 0 0 7 7 7 4 Domain of unknown function, DUF529 DNA_pol_E_B PF04042.16 EAN32559.1 - 5.1e-20 71.7 0.0 1.5e-19 70.2 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B FAINT PF04385.15 EAN32559.1 - 9.2e-07 28.8 17.0 6.7e-05 22.9 7.1 8.1 8 0 0 8 8 8 3 Domain of unknown function, DUF529 DUF2738 PF10927.8 EAN32559.1 - 0.0061 15.7 0.1 0.012 14.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2738) PPK2 PF03976.14 EAN32561.1 - 0.039 13.5 0.2 0.072 12.6 0.2 1.4 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) BAR_3 PF16746.5 EAN32562.1 - 0.0079 15.9 2.5 0.051 13.3 0.3 2.5 2 1 0 2 2 2 1 BAR domain of APPL family Sif PF06767.11 EAN32562.1 - 0.021 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Sif protein FAA_hydrolase_N PF09298.11 EAN32562.1 - 0.034 14.3 0.1 0.95 9.7 0.0 2.6 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal Med28 PF11594.8 EAN32562.1 - 0.062 13.4 6.1 0.077 13.1 1.4 2.8 2 1 1 3 3 3 0 Mediator complex subunit 28 HHH_5 PF14520.6 EAN32562.1 - 0.12 13.0 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain ATPase_2 PF01637.18 EAN32563.1 - 0.0076 16.2 0.0 0.0076 16.2 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EAN32563.1 - 0.008 16.2 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain DnaJ_C PF01556.18 EAN32564.1 - 2.5e-20 73.1 1.5 6e-16 58.9 0.8 2.6 1 1 1 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EAN32564.1 - 2.4e-07 31.0 15.2 5.8e-07 29.8 15.2 1.7 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 EAN32564.1 - 2.9e-05 24.1 2.9 0.00025 21.1 2.9 2.3 1 1 0 1 1 1 1 DnaJ domain Anti-TRAP PF15777.5 EAN32564.1 - 1.5 8.8 7.1 1 9.4 1.5 2.7 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein TPR_6 PF13174.6 EAN32565.1 - 4.8e-07 30.0 0.8 0.00016 22.1 0.9 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAN32565.1 - 1.2e-06 28.1 0.5 9.8e-05 22.2 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAN32565.1 - 1.9e-06 27.8 2.7 8.9e-06 25.7 3.0 1.7 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EAN32565.1 - 4.2e-06 26.9 0.4 4.5e-06 26.8 0.4 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EAN32565.1 - 9.3e-06 26.1 0.0 1.1e-05 25.8 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAN32565.1 - 2.9e-05 24.3 0.6 0.00014 22.0 0.6 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAN32565.1 - 4.9e-05 23.0 1.3 0.00088 19.0 1.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAN32565.1 - 0.00025 21.0 1.7 0.0017 18.4 0.8 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAN32565.1 - 0.00038 21.0 0.0 0.00042 20.9 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAN32565.1 - 0.0068 16.4 0.6 0.2 11.8 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Paf67 PF10255.9 EAN32565.1 - 0.0092 15.0 0.3 0.0095 15.0 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 PPR PF01535.20 EAN32565.1 - 0.011 15.9 0.1 4.1 7.9 0.0 2.2 2 0 0 2 2 2 0 PPR repeat TPR_17 PF13431.6 EAN32565.1 - 0.02 15.3 0.2 0.047 14.1 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAN32565.1 - 0.023 15.5 0.2 2.8 9.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.9 EAN32565.1 - 0.025 13.3 0.1 0.027 13.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_10 PF13374.6 EAN32565.1 - 0.042 13.7 0.5 0.1 12.5 0.2 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Ribosomal_L39 PF00832.20 EAN32566.1 - 2.1e-21 75.3 11.9 2.8e-21 74.9 11.9 1.2 1 0 0 1 1 1 1 Ribosomal L39 protein DUF747 PF05346.11 EAN32568.1 - 5.4e-102 341.5 21.2 7.7e-102 341.0 21.2 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DEAD PF00270.29 EAN32569.1 - 1.5e-39 135.6 0.7 4.9e-39 133.9 0.6 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN32569.1 - 2.2e-23 82.7 0.2 1.8e-22 79.7 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EAN32569.1 - 0.0036 16.1 0.3 0.0062 15.3 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 EAN32569.1 - 0.012 15.8 0.5 0.21 11.8 0.2 2.9 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 EAN32569.1 - 0.018 15.0 2.2 0.025 14.6 0.0 2.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Exo_endo_phos PF03372.23 EAN32570.1 - 9.5e-13 48.2 0.0 2.1e-12 47.1 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DXP_redisom_C PF08436.12 EAN32570.1 - 0.08 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain UQ_con PF00179.26 EAN32571.1 - 1.7e-43 147.7 0.1 1.9e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAN32571.1 - 0.0033 17.7 0.0 0.005 17.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain Cpn60_TCP1 PF00118.24 EAN32572.1 - 2.1e-151 504.9 4.7 2.4e-151 504.7 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Synaptobrevin PF00957.21 EAN32573.1 - 1.1e-20 73.2 2.0 2.3e-20 72.2 2.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EAN32573.1 - 1.1e-17 63.8 0.1 2.3e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF948 PF06103.11 EAN32573.1 - 2.5 8.4 4.6 9.4 6.6 0.6 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) IPP-2 PF04979.14 EAN32574.1 - 4.8e-13 50.0 14.2 5.7e-12 46.5 14.2 2.0 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF2199 PF09965.9 EAN32574.1 - 0.01 15.9 0.5 0.015 15.4 0.3 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) SLATT_5 PF18160.1 EAN32574.1 - 0.33 10.3 2.3 0.5 9.7 2.3 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 HA2 PF04408.23 EAN32575.1 - 2.9e-17 62.9 0.0 6e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EAN32575.1 - 2.8e-15 56.6 0.2 1.1e-14 54.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAN32575.1 - 5.3e-09 36.1 1.1 1.5e-08 34.6 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAN32575.1 - 0.00015 22.1 0.1 0.0012 19.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 EAN32575.1 - 0.00015 22.0 0.0 0.00034 20.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold SRP54 PF00448.22 EAN32575.1 - 0.0022 17.6 0.0 0.0051 16.4 0.0 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 EAN32575.1 - 0.014 15.9 0.3 0.1 13.1 0.2 2.2 1 1 1 2 2 2 0 ABC transporter AAA_19 PF13245.6 EAN32575.1 - 0.015 15.6 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 EAN32575.1 - 0.024 14.5 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Helicase T2SSE PF00437.20 EAN32575.1 - 0.025 13.7 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 EAN32575.1 - 0.029 14.4 0.0 0.14 12.2 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EAN32575.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain MgtE_N PF03448.17 EAN32575.1 - 0.1 13.2 0.1 0.21 12.2 0.1 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain AAA_29 PF13555.6 EAN32575.1 - 0.16 11.7 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MFS_1 PF07690.16 EAN32576.1 - 2.3e-09 36.7 37.0 3.9e-09 35.9 36.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Vma12 PF11712.8 EAN32576.1 - 0.0013 18.8 2.9 0.014 15.5 0.2 2.5 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Sugar_tr PF00083.24 EAN32576.1 - 0.0021 17.0 33.8 0.006 15.5 33.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1754 PF08555.10 EAN32577.1 - 0.0015 19.3 5.5 0.0015 19.3 5.5 2.0 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Gp5_C PF06715.12 EAN32577.1 - 0.25 11.6 4.2 0.84 9.9 0.5 3.1 3 0 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) Ribosomal_S17_N PF16205.5 EAN32581.1 - 1.6e-28 98.9 0.4 2.8e-28 98.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EAN32581.1 - 4.1e-25 87.7 1.0 4.1e-25 87.7 1.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 Nas2_N PF18265.1 EAN32582.1 - 1e-28 99.0 0.4 1.5e-28 98.6 0.4 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain Spc7 PF08317.11 EAN32582.1 - 0.035 13.0 0.8 0.043 12.7 0.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DASH_Spc34 PF08657.10 EAN32582.1 - 0.048 13.4 0.6 0.071 12.9 0.6 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF1104 PF06518.11 EAN32582.1 - 0.094 13.1 2.1 8.3 6.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) RRM_1 PF00076.22 EAN32583.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoIIM PF01944.17 EAN32584.1 - 0.016 15.3 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein M COX4 PF02936.14 EAN32584.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV CSN8_PSD8_EIF3K PF10075.9 EAN32586.1 - 2.7e-20 72.8 0.0 5.3e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EAN32586.1 - 0.067 12.6 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 SAC3/GANP family SAP PF02037.27 EAN32586.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 SAP domain Adaptin_N PF01602.20 EAN32587.1 - 1.6e-118 396.6 16.5 2.1e-118 396.2 16.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAN32587.1 - 3.2e-54 183.4 8.5 3.4e-53 180.0 0.2 2.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAN32587.1 - 4.6e-12 46.2 0.1 0.00015 22.1 0.0 5.5 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.22 EAN32587.1 - 4.6e-11 42.0 0.2 0.013 15.7 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat B2-adapt-app_C PF09066.10 EAN32587.1 - 1.3e-08 35.0 0.0 3.6e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain RTP1_C1 PF10363.9 EAN32587.1 - 0.0012 19.0 0.1 0.049 13.8 0.0 2.9 1 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 EAN32587.1 - 0.0033 17.4 0.2 1.2 9.2 0.0 4.3 2 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain GUN4_N PF16416.5 EAN32587.1 - 0.18 11.8 0.4 8.4 6.5 0.0 2.6 2 0 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal Ribosomal_L7Ae PF01248.26 EAN32588.1 - 1.3e-22 79.4 0.0 1.5e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family JAB PF01398.21 EAN32590.1 - 5.3e-08 32.8 0.0 3e-06 27.2 0.0 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PHB_acc PF05233.13 EAN32590.1 - 6.5 6.9 6.0 2.1 8.4 0.1 2.8 2 1 1 3 3 3 0 PHB accumulation regulatory domain FAINT PF04385.15 EAN32592.1 - 7.3e-13 48.4 51.5 2e-06 27.7 3.4 6.2 6 0 0 6 6 6 4 Domain of unknown function, DUF529 tRNA-synt_1 PF00133.22 EAN32593.1 - 1.4e-207 690.7 0.0 2.5e-207 689.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EAN32593.1 - 2.5e-20 73.0 1.3 4.6e-20 72.1 0.4 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EAN32593.1 - 4.4e-14 52.0 5.0 0.0012 17.6 0.7 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EAN32593.1 - 0.016 14.6 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Tenui_PVC2 PF06656.11 EAN32593.1 - 0.017 13.1 2.8 0.033 12.1 2.8 1.4 1 0 0 1 1 1 0 Tenuivirus PVC2 protein Cpn10 PF00166.21 EAN32594.1 - 2.3e-30 104.5 0.0 4.2e-14 52.4 0.0 2.1 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit NTP_transf_2 PF01909.23 EAN32595.1 - 4.6e-07 30.0 0.0 1.5e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EAN32595.1 - 0.00076 19.6 0.2 0.0024 18.0 0.2 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 EAN32595.1 - 0.026 14.6 0.7 0.21 11.7 0.0 2.6 2 1 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Sedlin_N PF04628.13 EAN32596.1 - 5.2e-40 136.6 0.2 6.4e-40 136.3 0.2 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EAN32596.1 - 0.042 13.8 0.1 0.069 13.1 0.1 1.3 1 0 0 1 1 1 0 Sybindin-like family FAST_1 PF06743.15 EAN32598.1 - 0.00021 21.1 2.6 8.6 6.4 0.0 4.8 3 1 2 5 5 5 4 FAST kinase-like protein, subdomain 1 DEAD PF00270.29 EAN32599.1 - 1.7e-38 132.1 0.0 7.1e-38 130.1 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN32599.1 - 6.4e-32 110.2 0.0 2.6e-30 105.0 0.0 3.0 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EAN32599.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_L27A PF00828.19 EAN32600.1 - 9.2e-23 81.3 0.0 1.2e-22 81.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Nucleoporin_FG PF13634.6 EAN32601.1 - 5.8e-10 39.9 176.9 0.00028 21.7 31.5 6.0 2 1 3 5 5 5 3 Nucleoporin FG repeat region NUC130_3NT PF08158.12 EAN32601.1 - 0.2 12.0 0.8 4.4 7.7 0.0 2.5 2 0 0 2 2 2 0 NUC130/3NT domain Thymidylate_kin PF02223.17 EAN32602.1 - 2.3e-43 148.1 0.0 2.6e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase PRK PF00485.18 EAN32602.1 - 0.0039 17.0 0.0 0.048 13.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EAN32602.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EAN32602.1 - 0.022 14.2 0.0 0.043 13.3 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 EAN32602.1 - 0.11 13.0 0.1 0.3 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain PPK2 PF03976.14 EAN32602.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Pkinase PF00069.25 EAN32603.1 - 1.4e-35 123.0 0.0 4.2e-22 78.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32603.1 - 3.4e-14 52.8 0.0 6.2e-06 25.7 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase DUF4733 PF15878.5 EAN32604.1 - 0.076 13.5 0.1 0.24 11.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4733) tRNA-synt_1c PF00749.21 EAN32605.1 - 1.2e-101 339.8 0.0 1.7e-101 339.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EAN32605.1 - 1.1e-43 149.2 0.0 1.9e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_L14 PF00238.19 EAN32606.1 - 1.3e-34 118.9 0.0 1.5e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SNARE PF05739.19 EAN32607.1 - 2.7e-10 40.1 0.2 2.7e-10 40.1 0.2 2.9 5 0 0 5 5 5 1 SNARE domain EcsC PF12787.7 EAN32607.1 - 0.024 14.3 0.0 0.38 10.4 0.0 2.1 1 1 0 1 1 1 0 EcsC protein family Syntaxin PF00804.25 EAN32607.1 - 0.025 14.3 12.4 0.13 11.9 1.7 2.7 1 1 1 2 2 2 0 Syntaxin DUF957 PF06117.11 EAN32607.1 - 0.034 13.7 0.1 0.085 12.4 0.1 1.7 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) Ribosomal_S15 PF00312.22 EAN32607.1 - 0.44 10.8 4.4 1.2 9.4 0.1 2.9 3 0 0 3 3 3 0 Ribosomal protein S15 DUF3161 PF11362.8 EAN32608.1 - 5.1e-43 144.9 1.3 5.1e-43 144.9 1.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3161) Fra10Ac1 PF09725.9 EAN32608.1 - 1.3e-41 141.6 5.4 1.3e-41 141.6 5.4 2.0 2 0 0 2 2 2 1 Folate-sensitive fragile site protein Fra10Ac1 SKA1 PF07160.12 EAN32608.1 - 0.00016 21.6 1.6 0.046 13.6 0.1 3.1 1 1 2 3 3 3 2 Spindle and kinetochore-associated protein 1 SKA2 PF16740.5 EAN32608.1 - 0.00059 19.6 1.2 0.0015 18.3 1.2 1.6 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 DUF3450 PF11932.8 EAN32608.1 - 0.072 12.4 0.9 0.11 11.8 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) LCCL PF03815.19 EAN32609.1 - 2.7e-22 78.7 0.6 2.7e-22 78.7 0.6 2.9 3 0 0 3 3 3 1 LCCL domain F5_F8_type_C PF00754.25 EAN32609.1 - 2.8e-10 40.4 0.4 2.7e-05 24.3 0.1 3.3 4 0 0 4 4 4 2 F5/8 type C domain COLFI PF01410.18 EAN32609.1 - 8.5e-07 28.5 0.1 2.6e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Fibrinogen_C PF00147.18 EAN32609.1 - 0.0012 18.7 0.8 0.029 14.2 0.0 2.8 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain MoaF PF10703.9 EAN32609.1 - 0.14 12.1 0.2 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 MoaF N-terminal domain Lebercilin PF15619.6 EAN32609.1 - 0.15 11.8 0.9 1.3 8.6 0.3 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Rxt3 PF08642.10 EAN32609.1 - 0.5 11.1 0.0 0.5 11.1 0.0 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 FAINT PF04385.15 EAN32610.1 - 0.17 12.0 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Bromodomain PF00439.25 EAN32611.1 - 1e-15 57.6 3.1 2.4e-15 56.4 3.1 1.7 1 0 0 1 1 1 1 Bromodomain SAGA-Tad1 PF12767.7 EAN32611.1 - 0.42 10.3 3.4 11 5.7 0.2 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Pox_MCEL PF03291.16 EAN32612.1 - 1e-41 143.2 11.3 1.5e-41 142.7 11.1 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.6 EAN32612.1 - 4.4e-11 42.8 0.1 1.4e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAN32612.1 - 1.3e-10 41.8 0.0 4.6e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAN32612.1 - 6.9e-09 36.4 0.0 2.4e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAN32612.1 - 8e-08 32.8 0.0 1.7e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAN32612.1 - 1.4e-07 31.5 0.0 2.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain EMP24_GP25L PF01105.24 EAN32613.1 - 3.7e-17 62.9 0.1 4e-17 62.7 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dynamitin PF04912.14 EAN32613.1 - 0.087 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Dynamitin ThiF PF00899.21 EAN32614.1 - 1.7e-46 158.6 0.0 4.8e-39 134.2 0.0 3.3 1 1 2 3 3 3 3 ThiF family Shikimate_DH PF01488.20 EAN32614.1 - 2.7e-08 33.9 0.4 0.0056 16.7 0.1 2.7 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.9 EAN32614.1 - 3.9e-07 30.3 1.5 0.0062 16.5 0.3 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EAN32614.1 - 0.00057 20.3 0.0 1.9 9.0 0.0 3.0 2 0 0 2 2 2 2 Putative NAD(P)-binding Pyr_redox PF00070.27 EAN32614.1 - 0.024 15.2 0.1 0.15 12.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EAN32614.1 - 0.079 12.6 0.0 0.77 9.4 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DEAD PF00270.29 EAN32615.1 - 4.6e-37 127.5 0.0 3.6e-36 124.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN32615.1 - 1.5e-27 96.1 2.2 8.8e-27 93.7 0.0 3.1 4 1 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN32615.1 - 3.5e-06 27.1 0.0 1.7e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit eIF-6 PF01912.18 EAN32616.1 - 4.1e-74 248.2 1.2 5.5e-74 247.8 1.2 1.2 1 0 0 1 1 1 1 eIF-6 family TypeIII_RM_meth PF12564.8 EAN32616.1 - 0.12 12.5 0.1 0.54 10.4 0.1 2.2 1 1 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit AP_endonuc_2 PF01261.24 EAN32617.1 - 2.6e-34 118.5 0.0 5.8e-34 117.4 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel putAbiC PF16872.5 EAN32618.1 - 0.048 14.4 1.1 5 7.9 0.0 2.6 2 0 0 2 2 2 0 Putative phage abortive infection protein HTH_34 PF13601.6 EAN32618.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF2321 PF10083.9 EAN32619.1 - 0.018 14.7 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) ANAPC4_WD40 PF12894.7 EAN32620.1 - 4.5e-06 26.9 2.3 18 5.7 0.0 6.0 5 1 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAN32620.1 - 0.0013 19.5 16.0 0.17 12.8 0.1 6.8 7 0 0 7 7 7 2 WD domain, G-beta repeat ELYS-bb PF16687.5 EAN32620.1 - 0.0028 16.3 0.1 0.092 11.3 0.0 2.2 2 0 0 2 2 2 2 beta-propeller of ELYS nucleoporin Atg8 PF02991.16 EAN32621.1 - 6.1e-22 77.8 0.1 1e-21 77.0 0.1 1.3 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EAN32621.1 - 0.014 15.8 0.1 0.034 14.5 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 tRNA_Me_trans PF03054.16 EAN32622.1 - 1.8e-97 326.4 0.3 2.9e-97 325.6 0.0 1.4 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 EAN32622.1 - 7.6e-05 22.5 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase SufE PF02657.15 EAN32622.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Fe-S metabolism associated domain ThiI PF02568.14 EAN32622.1 - 0.00032 20.3 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 EAN32622.1 - 0.014 14.6 0.0 6.1 5.9 0.0 2.6 2 0 0 2 2 2 0 NAD synthase QueC PF06508.13 EAN32622.1 - 0.021 14.3 0.0 0.1 12.0 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC TetR_C_4 PF08359.11 EAN32622.1 - 0.088 13.0 0.3 7.8 6.7 0.0 2.8 2 1 0 2 2 2 0 YsiA-like protein, C-terminal region Diphthami_syn_2 PF01902.17 EAN32622.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Diphthamide synthase DUF4884 PF16225.5 EAN32624.1 - 0.12 12.5 1.0 0.16 12.0 1.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4884) Proteasom_Rpn13 PF04683.13 EAN32626.1 - 2.6e-07 31.1 0.0 3.2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor UCH PF00443.29 EAN32627.1 - 1.5e-36 126.2 5.6 1.5e-36 126.2 5.6 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAN32627.1 - 2.1e-22 80.1 3.5 2.1e-22 80.1 3.5 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SHS2_Rpb7-N PF03876.17 EAN32628.1 - 1.3e-10 41.5 0.0 1.8e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Nop53 PF07767.11 EAN32629.1 - 2.4e-08 33.8 0.2 2.9e-08 33.5 0.2 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) AIP3 PF03915.13 EAN32629.1 - 0.0028 16.8 1.2 0.0035 16.5 1.2 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 DUF5601 PF18151.1 EAN32629.1 - 0.05 13.9 0.3 0.098 13.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) LETM1 PF07766.13 EAN32629.1 - 0.065 12.6 0.8 0.076 12.3 0.8 1.1 1 0 0 1 1 1 0 LETM1-like protein Ribosomal_S9 PF00380.19 EAN32630.1 - 1.4e-29 103.1 0.7 2.6e-29 102.2 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Vpu PF00558.19 EAN32630.1 - 0.19 11.5 0.7 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Vpu protein DASH_Spc34 PF08657.10 EAN32631.1 - 0.014 15.2 7.9 0.017 14.9 7.4 1.3 1 1 0 1 1 1 0 DASH complex subunit Spc34 TTRAP PF14203.6 EAN32631.1 - 0.04 13.9 1.3 0.19 11.7 0.4 2.2 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Prefoldin PF02996.17 EAN32631.1 - 0.079 12.9 5.3 0.091 12.7 1.9 2.5 1 1 1 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 EAN32631.1 - 0.92 9.7 13.7 0.75 10.0 6.9 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HALZ PF02183.18 EAN32631.1 - 1.7 8.9 6.3 7 7.0 2.5 3.0 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF3450 PF11932.8 EAN32631.1 - 2.8 7.2 7.3 2.8 7.2 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 EAN32631.1 - 3.5 7.8 10.0 2 8.5 3.9 2.7 2 0 0 2 2 2 0 bZIP transcription factor BLOC1_2 PF10046.9 EAN32631.1 - 7.5 6.9 13.7 1.6 9.1 5.5 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-CCHC_2 PF13696.6 EAN32632.1 - 5.6e-08 32.5 5.7 5.6e-08 32.5 5.7 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_4 PF15227.6 EAN32632.1 - 0.00021 21.3 15.4 0.00021 21.3 15.4 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EAN32632.1 - 0.00032 21.0 13.2 0.00032 21.0 13.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EAN32632.1 - 0.0029 17.6 11.7 0.0029 17.6 11.7 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAN32632.1 - 0.011 15.6 13.8 0.011 15.6 13.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAN32632.1 - 0.013 15.5 14.4 0.013 15.5 14.4 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-CCHC PF00098.23 EAN32632.1 - 0.11 12.6 3.9 0.34 11.1 3.9 1.9 1 0 0 1 1 1 0 Zinc knuckle zf_UBZ PF18439.1 EAN32632.1 - 0.11 12.1 2.4 0.31 10.7 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C3HC4 PF00097.25 EAN32632.1 - 0.35 10.8 18.8 0.14 12.1 15.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAN32632.1 - 0.77 9.7 17.4 0.14 12.0 11.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Metallophos PF00149.28 EAN32633.1 - 8.4e-40 137.4 0.0 1.1e-39 137.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAN32633.1 - 9.5e-21 74.0 2.8 9.5e-21 74.0 2.8 2.1 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain ABC1 PF03109.16 EAN32634.1 - 2.9e-23 82.3 0.1 6.6e-23 81.1 0.1 1.6 1 0 0 1 1 1 1 ABC1 family Beta-lactamase PF00144.24 EAN32634.1 - 2.1e-18 66.7 0.0 1e-17 64.4 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase mRNA_cap_enzyme PF01331.19 EAN32635.1 - 5.2e-38 130.8 0.0 8.5e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EAN32635.1 - 8.1e-16 58.6 0.0 1.8e-15 57.5 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Thioredoxin PF00085.20 EAN32636.1 - 1.8e-08 34.3 0.1 2.4e-05 24.2 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EAN32636.1 - 7.4e-08 32.5 2.2 0.058 13.3 0.0 3.2 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAN32636.1 - 1.4e-06 28.5 0.8 0.0081 16.5 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 EAN32636.1 - 0.0026 17.2 0.1 0.0067 15.8 0.1 1.7 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EAN32636.1 - 0.0043 17.5 0.0 0.46 11.0 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain KaiB PF07689.12 EAN32636.1 - 0.096 12.4 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 KaiB domain Hydrolase_4 PF12146.8 EAN32637.1 - 7.9e-06 25.3 0.2 0.0024 17.2 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 LIP PF03583.14 EAN32637.1 - 0.00038 19.9 0.0 0.00089 18.7 0.0 1.5 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_2 PF02230.16 EAN32637.1 - 0.00071 19.4 0.1 0.0041 16.9 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EAN32637.1 - 0.004 16.7 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 EAN32637.1 - 0.018 14.7 0.0 0.043 13.5 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EAN32637.1 - 0.03 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PINIT PF14324.6 EAN32637.1 - 0.12 12.7 1.3 0.19 12.0 1.3 1.3 1 0 0 1 1 1 0 PINIT domain eRF1_1 PF03463.15 EAN32638.1 - 6e-30 103.9 0.9 9.2e-30 103.3 0.1 1.7 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.15 EAN32638.1 - 2.7e-17 63.3 0.1 5e-17 62.4 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EAN32638.1 - 3.4e-09 37.1 0.0 7.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 2 ydhR PF08803.11 EAN32638.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR Pam16 PF03656.13 EAN32639.1 - 7.8e-09 35.6 0.1 8.8e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EAN32639.1 - 2.1e-05 24.6 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain RRP7 PF12923.7 EAN32640.1 - 3e-07 30.6 0.0 4.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF5093 PF17011.5 EAN32640.1 - 0.0044 17.3 0.5 0.0077 16.5 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5093) DUF3939 PF13075.6 EAN32640.1 - 0.036 14.1 0.9 0.052 13.6 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3939) DUF1573 PF07610.11 EAN32640.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1573) PCI PF01399.27 EAN32641.1 - 5.6e-06 26.8 0.0 1.6e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 PCI domain RNA_pol_Rpb4 PF03874.16 EAN32642.1 - 1.7e-11 44.5 0.5 8.8e-11 42.2 0.3 1.8 1 1 1 2 2 2 1 RNA polymerase Rpb4 DUF2959 PF11172.8 EAN32642.1 - 0.12 12.5 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Nucleoporin_FG PF13634.6 EAN32643.1 - 3.9e-32 111.0 182.7 2.9e-09 37.6 25.7 10.3 2 2 9 11 11 11 10 Nucleoporin FG repeat region Nsp1_C PF05064.13 EAN32643.1 - 1.9e-07 30.9 5.5 5e-07 29.5 5.5 1.7 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF4164 PF13747.6 EAN32643.1 - 0.67 10.3 5.5 3.7 7.9 0.7 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4164) DUF745 PF05335.13 EAN32643.1 - 1.2 8.8 4.4 2.4 7.8 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Sec34 PF04136.15 EAN32643.1 - 1.5 8.7 9.0 5.5 6.9 1.4 2.5 1 1 1 2 2 2 0 Sec34-like family Fib_alpha PF08702.10 EAN32643.1 - 5.4 7.2 9.9 10 6.3 3.2 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Lon_C PF05362.13 EAN32644.1 - 5.2e-61 205.8 4.1 6e-53 179.4 0.4 2.8 3 0 0 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EAN32644.1 - 4.4e-31 108.4 0.0 9.9e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EAN32644.1 - 3.7e-20 72.7 0.0 2.7e-19 69.9 0.0 2.5 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAN32644.1 - 2.6e-07 30.7 0.0 6.1e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAN32644.1 - 8.8e-06 26.2 0.1 8.4e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain ChlI PF13541.6 EAN32644.1 - 1.1e-05 25.3 0.1 2.3e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 EAN32644.1 - 0.00029 21.1 0.1 0.0081 16.4 0.1 2.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAN32644.1 - 0.00032 20.5 0.0 0.00077 19.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EAN32644.1 - 0.00033 20.0 0.1 0.00033 20.0 0.1 1.7 2 0 0 2 2 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EAN32644.1 - 0.0004 20.9 1.8 0.019 15.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 EAN32644.1 - 0.00066 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 EAN32644.1 - 0.00088 19.0 0.0 0.0029 17.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EAN32644.1 - 0.0029 17.7 0.0 0.016 15.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EAN32644.1 - 0.014 15.1 0.1 0.15 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EAN32644.1 - 0.022 15.3 1.8 0.87 10.1 0.2 2.8 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 EAN32644.1 - 0.022 14.8 0.7 0.13 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EAN32644.1 - 0.036 14.4 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 EAN32644.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EAN32644.1 - 0.082 12.8 1.8 0.19 11.6 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase AAA_19 PF13245.6 EAN32644.1 - 0.085 13.2 0.1 0.31 11.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EAN32644.1 - 0.088 12.3 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 EAN32644.1 - 0.09 12.3 0.0 0.27 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EAN32644.1 - 0.12 11.9 0.2 0.95 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF1493 PF07377.12 EAN32644.1 - 0.32 11.5 1.8 2 8.9 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) AAA_11 PF13086.6 EAN32644.1 - 4.3 7.1 10.6 1 9.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain LSM PF01423.22 EAN32645.1 - 1.2e-19 69.7 0.3 1.6e-19 69.4 0.3 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EAN32645.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain SM-ATX PF14438.6 EAN32645.1 - 0.16 12.2 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain PI-PLC-X PF00388.19 EAN32646.1 - 0.035 13.7 0.4 0.54 9.8 0.1 2.9 2 1 1 3 3 3 0 Phosphatidylinositol-specific phospholipase C, X domain Diphthamide_syn PF01866.17 EAN32647.1 - 1.7e-100 336.4 0.1 2.3e-100 336.0 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein YTH PF04146.15 EAN32648.1 - 1.6e-17 64.0 0.0 1.2e-15 57.9 0.0 2.2 1 1 0 1 1 1 1 YT521-B-like domain PWI PF01480.17 EAN32649.1 - 1.3e-27 95.9 0.0 1.8e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 PWI domain DcpS_C PF11969.8 EAN32650.1 - 0.00035 21.0 0.0 0.0032 17.9 0.0 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding N2227 PF07942.12 EAN32651.1 - 2.7e-67 226.8 1.6 2.2e-37 128.7 3.7 2.3 1 1 1 2 2 2 2 N2227-like protein Ribosomal_L9_N PF01281.19 EAN32651.1 - 1.3e-12 47.1 0.0 2.7e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Methyltransf_12 PF08242.12 EAN32651.1 - 5.7e-05 23.8 0.0 0.00044 20.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAN32651.1 - 0.011 16.4 0.0 0.029 15.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L9_C PF03948.14 EAN32651.1 - 0.12 12.9 0.1 0.26 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain Methyltransf_25 PF13649.6 EAN32651.1 - 0.18 12.5 0.0 0.45 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2752 PF10825.8 EAN32651.1 - 1 9.5 3.3 1.2 9.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) DSPc PF00782.20 EAN32652.1 - 0.0016 18.3 0.2 0.0042 16.9 0.2 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Ribosomal_60s PF00428.19 EAN32653.1 - 4e-23 81.8 2.0 4.7e-23 81.6 2.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein UBA_6 PF18039.1 EAN32653.1 - 0.091 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain UMP1 PF05348.11 EAN32654.1 - 1.7e-13 50.8 0.1 2e-13 50.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Torus PF16131.5 EAN32655.1 - 1.1e-05 26.1 0.3 1.1e-05 26.1 0.3 2.2 1 1 1 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 EAN32655.1 - 1.6e-05 24.8 3.0 1.6e-05 24.8 3.0 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 EAN32655.1 - 0.00098 18.9 0.9 0.00098 18.9 0.9 2.5 2 1 0 2 2 2 1 CCCH-type zinc finger UDG PF03167.19 EAN32656.1 - 1.9e-22 80.0 0.0 3e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RRM_1 PF00076.22 EAN32657.1 - 1.3e-37 127.5 0.1 1.4e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAN32657.1 - 0.00024 20.7 0.0 0.35 10.5 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAN32657.1 - 0.0011 18.9 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EAN32657.1 - 0.0071 16.4 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif PCI PF01399.27 EAN32659.1 - 1.1e-10 41.9 0.5 1.1e-10 41.9 0.5 3.5 4 0 0 4 4 4 1 PCI domain eIF3_N PF09440.10 EAN32659.1 - 0.00031 21.2 1.1 0.00072 20.0 0.1 2.2 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain COX_ARM PF06481.14 EAN32659.1 - 0.035 14.0 0.4 0.66 9.9 0.0 2.4 2 0 0 2 2 2 0 COX Aromatic Rich Motif RRM_1 PF00076.22 EAN32660.1 - 2.1e-26 91.5 0.1 3.6e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAN32660.1 - 5.8e-06 25.9 0.1 0.0013 18.3 0.1 2.1 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAN32660.1 - 0.0011 18.7 0.1 0.032 14.1 0.0 2.5 2 1 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 EAN32660.1 - 0.049 13.9 0.1 12 6.0 0.0 2.7 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Pkinase PF00069.25 EAN32661.1 - 6.4e-64 215.9 0.0 7.6e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32661.1 - 5.7e-40 137.2 0.0 7.1e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAN32661.1 - 0.00037 19.9 0.0 0.0016 17.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 EAN32661.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL EF-hand_7 PF13499.6 EAN32662.1 - 5.7e-06 26.7 9.7 0.00026 21.4 0.5 4.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EAN32662.1 - 7.1e-05 22.6 1.5 0.37 10.7 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EAN32662.1 - 0.00018 21.2 0.3 0.042 13.8 0.1 3.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EAN32662.1 - 0.00019 20.7 1.2 0.23 11.1 0.0 3.8 4 0 0 4 4 4 2 EF hand zf-CCCH_7 PF18586.1 EAN32662.1 - 0.055 13.8 0.1 0.33 11.3 0.1 2.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 TruB_N PF01509.18 EAN32663.1 - 1.9e-30 106.2 0.0 3.3e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PHB_acc_N PF07879.11 EAN32663.1 - 0.028 14.5 0.0 4.4 7.5 0.0 2.6 2 0 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain TruB_C_2 PF16198.5 EAN32663.1 - 0.16 12.2 0.0 0.76 10.0 0.0 2.1 1 1 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain LSM14 PF12701.7 EAN32665.1 - 7.9e-27 93.2 0.0 1.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 EAN32665.1 - 1.9e-08 34.3 1.3 3.2e-08 33.6 0.1 1.9 2 0 0 2 2 2 1 Ataxin 2 SM domain Apc15p PF05841.11 EAN32665.1 - 0.022 15.6 0.3 0.022 15.6 0.3 2.1 1 1 1 2 2 2 0 Apc15p protein ANAPC4_WD40 PF12894.7 EAN32666.1 - 8.3e-12 45.3 0.3 0.028 14.7 0.0 4.6 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAN32666.1 - 8.5e-05 23.3 9.9 0.12 13.3 0.0 6.2 6 1 0 6 6 6 1 WD domain, G-beta repeat PD40 PF07676.12 EAN32666.1 - 0.23 11.4 1.7 14 5.8 0.1 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat YtxH PF12732.7 EAN32667.1 - 0.18 12.4 0.2 0.35 11.4 0.2 1.4 1 0 0 1 1 1 0 YtxH-like protein YCII PF03795.14 EAN32667.1 - 0.19 12.1 0.0 0.42 11.1 0.0 1.5 1 0 0 1 1 1 0 YCII-related domain rve_3 PF13683.6 EAN32669.1 - 0.15 11.9 0.9 17 5.2 0.0 3.3 3 0 0 3 3 3 0 Integrase core domain ABC_tran PF00005.27 EAN32671.1 - 5.7e-31 107.9 0.0 2.7e-16 60.3 0.0 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAN32671.1 - 3.5e-09 36.7 22.3 3.5e-09 36.7 22.3 3.7 5 1 0 5 5 3 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 EAN32671.1 - 2.3e-06 27.6 0.1 0.032 14.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EAN32671.1 - 4.7e-05 22.8 0.1 0.085 12.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 EAN32671.1 - 0.00033 21.1 0.0 0.5 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EAN32671.1 - 0.0015 18.3 0.3 1.5 8.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EAN32671.1 - 0.006 16.6 0.1 0.35 11.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EAN32671.1 - 0.01 16.1 0.2 0.93 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EAN32671.1 - 0.012 15.6 0.1 2.3 8.2 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EAN32671.1 - 0.014 15.1 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EAN32671.1 - 0.025 13.8 0.3 0.77 8.9 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 EAN32671.1 - 0.04 14.4 4.0 3.9 7.9 0.2 2.9 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 EAN32671.1 - 0.043 14.2 0.1 5 7.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 EAN32671.1 - 0.055 13.4 0.8 6 6.8 0.1 2.8 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EAN32671.1 - 0.071 13.5 0.2 6.4 7.2 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 EAN32671.1 - 0.099 11.5 0.1 5 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.6 EAN32671.1 - 0.1 12.1 0.0 18 4.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EAN32671.1 - 0.11 11.5 0.0 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein SMC_N PF02463.19 EAN32671.1 - 0.12 11.8 0.6 0.34 10.3 0.1 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 EAN32671.1 - 0.13 12.2 0.0 20 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 EAN32671.1 - 0.19 10.7 0.1 2.3 7.1 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 EAN32671.1 - 0.34 10.7 7.5 1.1 9.0 0.0 4.0 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system MobB PF03205.14 EAN32671.1 - 0.42 10.5 1.6 2.5 8.0 0.3 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRP21_like_P PF12230.8 EAN32672.1 - 1.8e-37 129.3 6.7 3.9e-37 128.2 6.7 1.5 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EAN32672.1 - 9.6e-36 121.6 4.1 8.3e-18 64.1 0.1 2.5 2 0 0 2 2 2 2 Surp module Stealth_CR1 PF17101.5 EAN32672.1 - 0.2 11.4 0.7 0.58 9.9 0.7 1.8 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 DUF3340 PF11818.8 EAN32672.1 - 0.45 10.7 9.1 0.16 12.1 0.5 3.2 4 0 0 4 4 4 0 C-terminal domain of tail specific protease (DUF3340) ABC_tran PF00005.27 EAN32673.1 - 1.6e-32 112.9 0.0 1.4e-16 61.2 0.0 2.7 2 1 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EAN32673.1 - 7.1e-06 26.0 0.5 0.031 14.2 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EAN32673.1 - 1.2e-05 25.8 0.0 0.14 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EAN32673.1 - 2.8e-05 23.8 2.3 0.17 11.7 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 EAN32673.1 - 0.00018 22.0 0.2 2 9.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 EAN32673.1 - 0.00024 21.1 0.1 0.27 11.1 0.0 2.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EAN32673.1 - 0.00055 19.3 0.0 0.087 12.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 EAN32673.1 - 0.001 19.3 0.2 1 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAN32673.1 - 0.0017 18.1 0.3 0.17 11.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EAN32673.1 - 0.0036 17.8 5.1 0.6 10.6 0.5 3.2 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 EAN32673.1 - 0.0037 17.3 0.1 0.19 11.8 0.1 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase 120_Rick_ant PF12574.8 EAN32673.1 - 0.0059 15.8 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 120 KDa Rickettsia surface antigen Rad17 PF03215.15 EAN32673.1 - 0.0063 16.5 0.0 0.33 10.8 0.0 2.8 2 0 0 2 2 2 1 Rad17 P-loop domain T2SSE PF00437.20 EAN32673.1 - 0.0064 15.6 0.1 1.1 8.2 0.2 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MeaB PF03308.16 EAN32673.1 - 0.0097 14.9 0.2 0.069 12.1 0.2 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 EAN32673.1 - 0.011 15.3 0.0 1.9 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 EAN32673.1 - 0.015 15.1 1.0 0.93 9.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 EAN32673.1 - 0.019 15.3 0.0 2.6 8.5 0.0 3.0 2 0 0 2 2 2 0 RNA helicase SMC_N PF02463.19 EAN32673.1 - 0.02 14.3 2.7 0.14 11.6 0.1 3.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 EAN32673.1 - 0.023 13.9 0.2 0.5 9.5 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 EAN32673.1 - 0.029 14.3 0.1 3.5 7.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 EAN32673.1 - 0.046 13.6 0.7 8.3 6.3 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA PF00004.29 EAN32673.1 - 0.047 14.1 0.1 1.7 9.1 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EAN32673.1 - 0.049 13.7 0.1 4.3 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EAN32673.1 - 0.053 13.1 0.6 2.1 7.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EAN32673.1 - 0.087 12.6 2.1 9.3 5.9 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.7 EAN32673.1 - 0.088 11.7 0.9 14 4.5 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain AAA_7 PF12775.7 EAN32673.1 - 0.099 12.2 0.8 6 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 EAN32673.1 - 0.1 11.7 0.6 6.5 5.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 EAN32673.1 - 0.11 12.2 0.1 13 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EAN32673.1 - 0.35 10.9 5.2 0.39 10.8 0.3 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain MobB PF03205.14 EAN32673.1 - 0.44 10.5 1.3 1.3 8.9 0.4 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 EAN32674.1 - 1.1e-32 113.4 0.0 1.1e-17 64.8 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAN32674.1 - 6.8e-09 35.8 16.4 6.8e-09 35.8 16.4 4.1 4 0 0 4 4 3 1 ABC transporter transmembrane region AAA_16 PF13191.6 EAN32674.1 - 7e-06 26.5 0.0 0.1 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EAN32674.1 - 8.7e-06 26.4 1.2 0.15 12.5 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EAN32674.1 - 2.2e-05 24.5 0.7 0.2 11.4 0.4 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAN32674.1 - 8.3e-05 22.1 2.5 0.031 13.7 0.0 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAN32674.1 - 8.7e-05 22.2 0.8 0.41 10.4 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EAN32674.1 - 9.8e-05 22.3 0.5 0.34 10.8 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase ATPase_2 PF01637.18 EAN32674.1 - 0.00011 22.3 0.3 0.24 11.3 0.0 3.1 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea T2SSE PF00437.20 EAN32674.1 - 0.00033 19.8 0.2 0.032 13.3 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 EAN32674.1 - 0.00036 19.9 0.0 0.16 11.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 EAN32674.1 - 0.0012 19.2 0.3 1.6 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 EAN32674.1 - 0.0027 17.0 0.3 0.044 13.0 0.1 2.5 2 0 0 2 2 2 1 NB-ARC domain MeaB PF03308.16 EAN32674.1 - 0.0045 16.0 0.0 0.075 12.0 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EAN32674.1 - 0.005 16.6 0.2 0.32 10.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAN32674.1 - 0.0055 16.6 0.3 1.5 8.7 0.2 2.7 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 EAN32674.1 - 0.018 15.4 0.1 1.5 9.3 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EAN32674.1 - 0.021 15.4 0.2 5.2 7.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAN32674.1 - 0.033 13.8 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EAN32674.1 - 0.033 14.3 0.4 2.1 8.5 0.3 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 EAN32674.1 - 0.054 13.5 0.2 4.8 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EAN32674.1 - 0.058 13.3 0.1 0.6 10.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain cobW PF02492.19 EAN32674.1 - 0.066 12.8 1.1 2.5 7.7 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EAN32674.1 - 0.068 13.6 1.0 5.1 7.5 0.0 3.1 3 0 0 3 3 2 0 RNA helicase ATP_bind_1 PF03029.17 EAN32674.1 - 0.075 12.8 0.3 13 5.5 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 EAN32674.1 - 0.077 12.9 1.9 7.1 6.5 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 EAN32674.1 - 0.077 13.0 0.1 5.9 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EAN32674.1 - 0.098 13.0 0.8 8.3 6.7 0.2 2.7 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 EAN32674.1 - 0.1 12.6 0.0 15 5.6 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EAN32674.1 - 0.12 12.1 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EAN32674.1 - 0.17 11.3 0.1 5 6.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF87 PF01935.17 EAN32674.1 - 0.35 10.9 4.4 0.34 11.0 1.1 2.6 2 1 1 3 3 3 0 Helicase HerA, central domain Ribosomal_L20 PF00453.18 EAN32675.1 - 3e-21 75.5 0.2 3.6e-21 75.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Sec62 PF03839.16 EAN32676.1 - 3.2e-30 105.3 3.9 4.6e-30 104.8 3.9 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 DUF1097 PF06496.11 EAN32676.1 - 0.74 9.9 9.3 1.3 9.2 9.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1097) INSC_LBD PF16748.5 EAN32676.1 - 1.5 8.4 4.7 2.7 7.5 2.0 2.3 2 0 0 2 2 2 0 Inscuteable LGN-binding domain MgtE PF01769.16 EAN32676.1 - 3.5 8.0 8.0 3.1 8.2 6.6 1.5 2 0 0 2 2 2 0 Divalent cation transporter ubiquitin PF00240.23 EAN32677.1 - 0.00098 18.8 5.1 0.17 11.7 0.7 3.3 2 1 0 2 2 2 2 Ubiquitin family TRAM_LAG1_CLN8 PF03798.16 EAN32678.1 - 5.1e-31 108.0 22.2 5.1e-31 108.0 22.2 1.5 2 0 0 2 2 2 1 TLC domain Cytochrom_C PF00034.21 EAN32679.1 - 5.2e-15 56.4 0.0 6.6e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EAN32679.1 - 2.4e-06 27.8 0.8 7.8e-06 26.1 0.8 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EAN32679.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 EAN32679.1 - 0.043 13.4 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 OB_NTP_bind PF07717.16 EAN32680.1 - 0.15 12.4 0.1 0.35 11.3 0.1 1.6 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold HOIP-UBA PF16678.5 EAN32681.1 - 0.00087 19.3 0.1 0.0017 18.4 0.1 1.4 1 0 0 1 1 1 1 HOIP UBA domain pair Macoilin PF09726.9 EAN32681.1 - 0.43 9.1 16.0 0.58 8.7 16.0 1.3 1 0 0 1 1 1 0 Macoilin family Utp14 PF04615.13 EAN32681.1 - 8 4.9 15.3 11 4.5 15.3 1.2 1 0 0 1 1 1 0 Utp14 protein Pkinase PF00069.25 EAN32682.1 - 5.4e-80 268.5 0.2 1.1e-79 267.5 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32682.1 - 1.6e-37 129.2 0.0 3.1e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EAN32682.1 - 1.5e-23 83.0 3.6 1.4e-12 47.9 3.3 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAN32682.1 - 8.9e-23 78.1 8.5 5.8e-06 25.5 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EAN32682.1 - 2.9e-19 67.3 3.2 2.4e-05 23.9 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EAN32682.1 - 7.1e-18 63.2 7.3 4.3e-05 22.8 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EAN32682.1 - 8.3e-15 54.4 5.4 1.6e-06 27.8 1.6 4.8 4 1 1 5 5 4 4 EF-hand domain pair EF-hand_4 PF12763.7 EAN32682.1 - 7e-06 25.9 0.4 0.066 13.2 0.0 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EAN32682.1 - 0.00041 20.6 0.3 1 9.7 0.0 3.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 EAN32682.1 - 0.0025 17.2 0.1 0.0062 15.9 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAN32682.1 - 0.023 14.6 0.4 0.082 12.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAN32682.1 - 0.025 14.1 0.0 0.025 14.1 0.0 2.8 3 0 0 3 3 3 0 Choline/ethanolamine kinase Oxysterol_BP PF01237.18 EAN32684.1 - 4.1e-122 407.6 0.5 8.8e-122 406.5 0.5 1.6 1 0 0 1 1 1 1 Oxysterol-binding protein AAA_16 PF13191.6 EAN32685.1 - 5.2e-07 30.2 0.0 1.4e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EAN32685.1 - 1.3e-05 25.2 0.3 2.3e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EAN32685.1 - 1.9e-05 25.0 0.2 3.8e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EAN32685.1 - 9.2e-05 22.4 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 EAN32685.1 - 0.00075 19.9 0.0 0.0028 18.1 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EAN32685.1 - 0.0021 17.5 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein T2SSE PF00437.20 EAN32685.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DpnI_C PF17726.1 EAN32685.1 - 0.035 14.2 2.3 9.4 6.4 0.2 3.5 3 0 0 3 3 3 0 Dam-replacing HTH domain AAA_33 PF13671.6 EAN32685.1 - 0.044 13.9 0.1 0.19 11.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAN32685.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.31 EAN32686.1 - 2.4e-07 30.8 0.0 6.9e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAN32686.1 - 1.6e-05 25.0 0.2 8.5e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4844 PF16133.5 EAN32686.1 - 0.0094 16.5 2.1 0.027 15.0 2.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4844) SID PF11778.8 EAN32686.1 - 0.51 10.4 5.5 2 8.6 2.0 2.5 2 0 0 2 2 2 0 Septation initiation Aha1_N PF09229.11 EAN32687.1 - 3.8e-23 82.2 0.1 3.8e-23 82.2 0.1 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal TPR_1 PF00515.28 EAN32687.1 - 1.3e-09 37.5 14.9 1.9e-05 24.2 0.9 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAN32687.1 - 7.2e-06 25.7 16.3 0.00069 19.5 0.7 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAN32687.1 - 1.8e-05 25.2 0.3 0.00027 21.4 0.6 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAN32687.1 - 4.1e-05 23.8 0.6 1.9 8.8 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAN32687.1 - 0.00012 22.6 0.7 0.00055 20.5 0.2 2.3 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 EAN32687.1 - 0.0047 17.0 0.4 0.056 13.5 0.4 2.5 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_14 PF13428.6 EAN32687.1 - 0.014 16.2 2.4 0.31 12.0 0.2 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EAN32687.1 - 0.014 15.7 0.9 0.014 15.7 0.9 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAN32687.1 - 0.019 15.2 3.2 0.05 13.8 1.9 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EAN32687.1 - 0.019 14.6 10.8 0.36 10.5 2.9 3.6 2 1 1 3 3 3 0 TPR repeat TPR_8 PF13181.6 EAN32687.1 - 0.023 14.9 0.5 0.023 14.9 0.5 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 EAN32687.1 - 0.027 14.8 0.1 0.084 13.2 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAN32687.1 - 0.027 14.6 0.1 0.065 13.4 0.0 1.7 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAN32687.1 - 0.11 13.2 1.3 21 6.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAN32687.1 - 0.69 10.0 7.5 0.31 11.1 0.5 3.1 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF357 PF04010.13 EAN32687.1 - 0.75 9.9 3.3 3.4 7.8 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DUF4407 PF14362.6 EAN32687.1 - 1.2 8.5 4.9 1.9 7.8 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RCC1 PF00415.18 EAN32688.1 - 2.8e-17 63.1 0.4 2.3e-06 28.1 0.2 4.3 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 EAN32688.1 - 1.1e-11 43.4 27.7 5.7e-05 22.6 0.2 6.8 7 0 0 7 7 7 5 IQ calmodulin-binding motif RCC1_2 PF13540.6 EAN32688.1 - 1.2e-09 37.7 14.8 2.2e-06 27.3 2.0 3.4 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat CwfJ_C_2 PF04676.14 EAN32689.1 - 1.2e-15 58.1 0.0 2.1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EAN32689.1 - 8.8e-11 41.7 0.1 3e-09 36.8 0.1 2.2 1 1 1 2 2 2 2 Protein similar to CwfJ C-terminus 1 FAINT PF04385.15 EAN32690.1 - 0.00011 22.2 15.3 0.045 13.8 6.1 3.2 2 1 0 2 2 2 2 Domain of unknown function, DUF529 Ribo_biogen_C PF04034.13 EAN32691.1 - 4.5e-43 146.0 0.0 6.7e-43 145.4 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EAN32691.1 - 9.9e-11 41.3 0.1 1.6e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI WD40 PF00400.32 EAN32692.1 - 8.8e-21 73.9 8.1 5.6e-05 23.8 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN32692.1 - 3.9e-06 27.1 0.1 0.27 11.6 0.0 4.6 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAN32692.1 - 0.00027 20.9 2.0 0.36 10.7 0.1 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAN32692.1 - 0.077 12.0 0.0 8.9 5.2 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EAN32692.1 - 0.1 12.2 0.2 1.8 8.1 0.0 3.0 3 1 0 3 3 3 0 PQQ-like domain MSG PF02349.15 EAN32692.1 - 0.22 11.8 1.4 0.47 10.7 1.4 1.5 1 0 0 1 1 1 0 Major surface glycoprotein Carb_anhydrase PF00194.21 EAN32695.1 - 1.8e-21 76.8 2.2 2.2e-16 60.2 0.2 3.4 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase CTNNBL PF08216.11 EAN32696.1 - 2.8e-21 75.7 1.7 1e-20 73.8 0.0 2.5 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear RICTOR_N PF14664.6 EAN32696.1 - 0.019 14.0 0.3 0.69 8.8 0.0 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term UNC45-central PF11701.8 EAN32696.1 - 0.032 14.2 0.0 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central PAP_central PF04928.17 EAN32696.1 - 0.22 10.4 0.9 0.45 9.4 0.9 1.4 1 0 0 1 1 1 0 Poly(A) polymerase central domain BLI1 PF17324.2 EAN32696.1 - 2.6 8.7 9.5 5.9 7.6 1.9 2.9 2 0 0 2 2 2 0 BLOC-1 interactor 1 DnaJ PF00226.31 EAN32697.1 - 1.3e-10 41.3 0.1 3.8e-10 39.8 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 EAN32697.1 - 3.5e-05 23.4 4.1 0.027 14.3 0.9 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAN32697.1 - 0.00097 19.1 5.5 0.031 14.4 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 EAN32697.1 - 0.005 16.9 0.2 0.031 14.4 0.1 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Apc15p PF05841.11 EAN32697.1 - 0.029 15.2 1.6 0.093 13.5 1.6 1.8 1 0 0 1 1 1 0 Apc15p protein Tropomyosin_1 PF12718.7 EAN32697.1 - 5.5 7.1 9.0 0.84 9.8 2.3 2.9 3 0 0 3 3 3 0 Tropomyosin like Clat_adaptor_s PF01217.20 EAN32699.1 - 1.4e-38 132.0 3.9 1.6e-38 131.8 3.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RelA_SpoT PF04607.17 EAN32699.1 - 0.11 12.8 0.3 0.17 12.2 0.3 1.4 1 0 0 1 1 1 0 Region found in RelA / SpoT proteins TPPK_C PF12555.8 EAN32702.1 - 0.31 11.1 0.0 0.31 11.1 0.0 3.0 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal DUF501 PF04417.12 EAN32704.1 - 6.5e-16 58.4 0.8 7.5e-09 35.5 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF501) Wax2_C PF12076.8 EAN32704.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain Zip PF02535.22 EAN32704.1 - 2.8 7.0 7.0 1.2 8.3 4.3 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter NDK PF00334.19 EAN32705.1 - 5.8e-51 172.0 0.0 6.6e-51 171.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SRP54 PF00448.22 EAN32706.1 - 3.3e-55 186.8 0.5 4.9e-55 186.2 0.5 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 EAN32706.1 - 3e-09 37.2 7.7 0.00022 21.3 0.1 2.2 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal AAA_30 PF13604.6 EAN32706.1 - 2.7e-05 24.0 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EAN32706.1 - 4.5e-05 22.6 0.7 0.00021 20.4 0.3 2.2 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EAN32706.1 - 0.00021 21.3 0.9 0.00047 20.2 0.4 2.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 EAN32706.1 - 0.00029 20.8 3.6 0.015 15.2 0.1 3.0 4 0 0 4 4 4 1 NTPase AAA_31 PF13614.6 EAN32706.1 - 0.0007 19.6 7.2 0.0053 16.7 0.1 3.2 2 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EAN32706.1 - 0.0011 19.3 0.0 0.005 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAN32706.1 - 0.0012 19.2 0.0 0.0028 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ArsA_ATPase PF02374.15 EAN32706.1 - 0.002 17.4 0.3 0.1 11.8 0.3 2.3 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 EAN32706.1 - 0.0036 16.8 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_17 PF13207.6 EAN32706.1 - 0.015 15.8 0.0 0.045 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAN32706.1 - 0.066 13.6 0.3 0.61 10.5 0.0 2.7 3 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAN32706.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAN32706.1 - 0.14 12.1 0.1 0.42 10.5 0.1 1.8 1 1 0 1 1 1 0 NACHT domain ORC6 PF05460.13 EAN32706.1 - 3.3 6.9 12.9 4.8 6.4 12.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Big_2 PF02368.18 EAN32707.1 - 0.27 11.2 5.8 4.5 7.2 1.8 2.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) SEP PF08059.13 EAN32708.1 - 3.6e-08 33.8 0.0 1.4e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EAN32708.1 - 0.0097 16.1 0.1 0.032 14.4 0.1 1.9 1 1 0 1 1 1 1 UBX domain Ubiquitin_4 PF18036.1 EAN32708.1 - 0.026 14.6 0.5 0.067 13.2 0.5 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain ubiquitin PF00240.23 EAN32708.1 - 0.61 9.9 6.9 0.66 9.8 0.2 3.0 3 0 0 3 3 3 0 Ubiquitin family I_LWEQ PF01608.17 EAN32708.1 - 2.8 8.2 5.7 6.8 6.9 5.7 1.6 1 0 0 1 1 1 0 I/LWEQ domain Sigma_reg_C PF13791.6 EAN32711.1 - 0.047 13.9 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 Sigma factor regulator C-terminal SUI1 PF01253.22 EAN32712.1 - 1.1e-17 64.3 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Peptidase_M41 PF01434.18 EAN32713.1 - 1.9e-59 200.7 0.5 8.5e-59 198.6 0.0 2.2 3 0 0 3 3 3 1 Peptidase family M41 AAA PF00004.29 EAN32713.1 - 3.3e-43 147.3 0.3 1.2e-42 145.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAN32713.1 - 3.7e-12 45.8 0.1 8.2e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EAN32713.1 - 1e-05 25.8 0.0 0.021 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EAN32713.1 - 0.00012 22.1 0.0 0.0005 20.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EAN32713.1 - 0.00022 20.5 0.0 0.00044 19.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 EAN32713.1 - 0.00028 20.7 0.0 0.00069 19.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EAN32713.1 - 0.003 17.7 0.0 0.015 15.4 0.0 2.2 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EAN32713.1 - 0.0036 17.7 0.1 0.039 14.3 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 EAN32713.1 - 0.0043 17.5 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain FtsH_ext PF06480.15 EAN32713.1 - 0.0059 17.0 0.4 0.0059 17.0 0.4 3.1 3 1 0 3 3 2 1 FtsH Extracellular IstB_IS21 PF01695.17 EAN32713.1 - 0.0062 16.3 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EAN32713.1 - 0.011 16.0 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAN32713.1 - 0.011 16.3 0.0 0.037 14.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EAN32713.1 - 0.021 14.2 0.1 0.047 13.1 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EAN32713.1 - 0.24 11.1 3.1 7.2 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cytochrom_NNT PF03264.14 EAN32713.1 - 0.27 10.9 0.7 0.51 10.0 0.7 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DEAD PF00270.29 EAN32714.1 - 1.7e-33 115.8 0.0 1.3e-31 109.7 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN32714.1 - 6e-21 74.9 0.1 3.3e-20 72.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EAN32714.1 - 4.8e-16 58.7 0.1 1.1e-15 57.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EAN32714.1 - 2.6e-05 24.3 0.1 2.6e-05 24.3 0.1 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAN32714.1 - 0.031 14.5 0.1 0.58 10.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain ThiF PF00899.21 EAN32716.1 - 1.4e-44 152.3 0.5 2.1e-44 151.8 0.5 1.2 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 EAN32716.1 - 0.0054 17.2 0.1 0.016 15.7 0.1 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EAN32716.1 - 0.0066 15.8 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PglD_N PF17836.1 EAN32716.1 - 0.026 15.2 0.0 0.056 14.1 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain Sacchrp_dh_NADP PF03435.18 EAN32716.1 - 0.028 14.7 3.2 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 EAN32716.1 - 0.043 13.1 0.8 0.076 12.2 0.8 1.4 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EAN32716.1 - 0.046 13.3 0.1 0.097 12.2 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EAN32716.1 - 0.12 12.0 0.2 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF4342 PF14242.6 EAN32716.1 - 0.46 10.5 1.9 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Phi_1 PF04674.12 EAN32717.1 - 0.083 12.2 0.8 0.16 11.2 0.1 1.7 2 0 0 2 2 2 0 Phosphate-induced protein 1 conserved region FlaC_arch PF05377.11 EAN32717.1 - 0.5 10.8 3.1 22 5.6 0.0 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) tRNA-synt_His PF13393.6 EAN32718.1 - 3e-37 128.5 0.0 4.2e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 EAN32718.1 - 0.00016 21.7 0.0 0.0002 21.4 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) MerR_1 PF13411.6 EAN32718.1 - 0.0094 16.0 0.1 0.043 13.9 0.0 2.2 2 0 0 2 2 2 1 MerR HTH family regulatory protein eIF2A PF08662.11 EAN32719.1 - 1.6e-53 181.5 2.3 7.7e-52 176.0 0.2 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_C1 PF02167.15 EAN32719.1 - 0.16 11.7 0.9 0.27 10.9 0.9 1.3 1 0 0 1 1 1 0 Cytochrome C1 family SpoVAC_SpoVAEB PF03862.13 EAN32719.1 - 0.19 12.0 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 SpoVAC/SpoVAEB sporulation membrane protein PNP_UDP_1 PF01048.20 EAN32720.1 - 2.7e-19 69.3 0.0 3.5e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.20 EAN32721.1 - 8.9e-21 74.2 0.0 9.8e-21 74.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.20 EAN32722.1 - 0.0091 15.3 0.0 0.013 14.8 0.0 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.20 EAN32723.1 - 2.8e-18 66.0 0.0 2.9e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Brix PF04427.18 EAN32724.1 - 8.2e-35 120.7 1.1 1.3e-34 120.0 1.1 1.2 1 0 0 1 1 1 1 Brix domain Rep_fac-A_C PF08646.10 EAN32726.1 - 1.2e-37 128.8 1.5 3.1e-37 127.6 1.5 1.7 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EAN32726.1 - 8.7e-13 48.0 0.5 7.4e-10 38.6 0.1 2.8 2 0 0 2 2 2 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 EAN32726.1 - 5.9e-10 39.0 0.1 1.3e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain DUF223 PF02721.14 EAN32726.1 - 2.3e-05 24.6 3.7 4.3e-05 23.7 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF223 DUF2318 PF10080.9 EAN32726.1 - 0.027 14.6 0.8 0.064 13.4 0.8 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) HU-DNA_bdg PF14848.6 EAN32726.1 - 0.077 13.0 1.0 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 DNA-binding domain Diphthami_syn_2 PF01902.17 EAN32727.1 - 3.7e-40 137.8 0.3 8.4e-40 136.6 0.3 1.5 1 1 0 1 1 1 1 Diphthamide synthase ATP-synt_F PF01990.17 EAN32728.1 - 5.1e-29 100.5 0.3 6e-29 100.2 0.3 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit eIF-5_eIF-2B PF01873.17 EAN32728.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain found in IF2B/IF5 DHHC PF01529.20 EAN32729.1 - 2.7e-35 121.4 20.3 9.1e-35 119.7 12.8 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase NinF PF05810.12 EAN32729.1 - 0.13 12.1 1.6 0.27 11.1 1.6 1.5 1 0 0 1 1 1 0 NinF protein ANAPC4_WD40 PF12894.7 EAN32731.1 - 5e-09 36.4 0.5 0.0061 16.8 0.1 3.9 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAN32731.1 - 0.31 12.0 14.1 4.8 8.2 0.8 6.0 5 2 1 6 6 6 0 WD domain, G-beta repeat CDT1 PF08839.11 EAN32732.1 - 7.9e-11 42.6 0.0 1.8e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like DUF4634 PF15465.6 EAN32732.1 - 0.48 10.7 3.8 3.5 7.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4634) Mito_carr PF00153.27 EAN32733.1 - 8.3e-53 176.3 0.9 1.6e-17 63.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP1_OBG PF01018.22 EAN32734.1 - 1.6e-21 76.5 0.2 2.2e-21 76.1 0.2 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 EAN32734.1 - 1.3e-12 47.8 0.0 2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAN32734.1 - 2.9e-08 33.4 0.0 4.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 EAN32734.1 - 8.9e-06 25.2 0.1 1.2e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAN32734.1 - 0.0022 17.5 0.1 0.0039 16.6 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EAN32734.1 - 0.0027 17.3 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.21 EAN32734.1 - 0.0034 16.9 0.0 0.0061 16.0 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 EAN32734.1 - 0.019 15.1 1.7 0.23 11.5 0.1 2.1 1 1 1 2 2 2 0 Dynamin family Ploopntkinase3 PF18751.1 EAN32734.1 - 0.058 13.3 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Ubiq_cyt_C_chap PF03981.12 EAN32735.1 - 4.2e-12 46.3 0.1 5.8e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone QueT PF06177.11 EAN32737.1 - 0.1 13.0 3.7 1.1 9.7 3.7 2.0 1 1 0 1 1 1 0 QueT transporter FAM104 PF15434.6 EAN32737.1 - 0.16 12.6 0.3 0.22 12.1 0.3 1.1 1 0 0 1 1 1 0 Family 104 DUF3007 PF11460.8 EAN32738.1 - 1.7 9.0 4.5 0.78 10.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) RNase_T PF00929.24 EAN32739.1 - 6.5e-14 52.8 0.0 9.4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EAN32739.1 - 0.028 14.2 0.2 0.078 12.7 0.1 1.7 2 0 0 2 2 2 0 3'-5' exonuclease Mon1 PF03164.14 EAN32741.1 - 6.8e-29 101.2 0.1 7.7e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Longin PF13774.6 EAN32741.1 - 0.033 14.2 0.1 0.057 13.5 0.1 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain Mon1 PF03164.14 EAN32742.1 - 0.0051 15.9 0.0 0.0051 15.9 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 ABC_tran PF00005.27 EAN32743.1 - 1.5e-34 119.5 0.0 3.8e-34 118.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EAN32743.1 - 4.6e-28 98.6 17.3 6.2e-28 98.2 17.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EAN32743.1 - 6.1e-07 29.1 0.0 0.00032 20.2 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAN32743.1 - 6.2e-05 22.9 0.3 0.053 13.3 0.4 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAN32743.1 - 0.0014 18.3 0.1 0.005 16.6 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EAN32743.1 - 0.0047 17.4 0.3 0.014 15.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EAN32743.1 - 0.016 14.9 0.3 0.058 13.1 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EAN32743.1 - 0.025 14.8 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EAN32743.1 - 0.027 14.5 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 EAN32743.1 - 0.039 13.9 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 EAN32743.1 - 0.043 13.5 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAN32743.1 - 0.045 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 EAN32743.1 - 0.059 12.5 0.0 0.14 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 EAN32743.1 - 0.071 13.2 1.3 0.12 12.5 0.0 2.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase RsbU_N PF08673.10 EAN32744.1 - 0.0025 17.9 0.4 0.033 14.3 0.1 2.7 2 0 0 2 2 2 1 Phosphoserine phosphatase RsbU, N-terminal domain Pkinase PF00069.25 EAN32745.1 - 1.9e-09 37.3 0.0 5.7e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Rcd1 PF04078.13 EAN32746.1 - 6.5e-113 376.3 2.0 9.9e-113 375.7 2.0 1.3 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Tubulin PF00091.25 EAN32747.1 - 3e-69 233.2 0.0 8.6e-69 231.7 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAN32747.1 - 2.5e-42 144.0 0.2 3.8e-42 143.4 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EAN32747.1 - 4.4e-05 23.8 0.0 0.00013 22.3 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EAN32747.1 - 0.0024 17.1 0.1 0.0082 15.4 0.0 1.8 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EAN32747.1 - 0.0036 17.0 0.0 0.0086 15.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain FHA PF00498.26 EAN32748.1 - 3.5e-17 62.5 0.0 7.5e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EAN32748.1 - 1.1e-09 38.5 0.0 2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain GAS PF13851.6 EAN32749.1 - 0.0055 16.1 6.7 0.0055 16.1 6.7 2.5 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF2353 PF09789.9 EAN32749.1 - 0.028 13.8 16.2 0.018 14.4 2.8 2.3 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DivIVA PF05103.13 EAN32749.1 - 0.03 14.4 11.7 0.043 13.9 0.3 3.3 2 1 1 3 3 3 0 DivIVA protein CCDC144C PF14915.6 EAN32749.1 - 0.074 12.2 21.2 0.13 11.4 5.0 2.7 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region GCV_H PF01597.19 EAN32749.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein Jnk-SapK_ap_N PF09744.9 EAN32749.1 - 0.37 11.0 18.1 0.13 12.5 5.7 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 EAN32749.1 - 0.79 9.7 22.5 0.3 11.1 8.9 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 EAN32749.1 - 1.3 9.5 15.8 0.25 11.8 5.4 3.0 2 0 0 2 2 2 0 Cell division protein ZapB PRKG1_interact PF15898.5 EAN32749.1 - 1.7 9.6 20.2 10 7.1 9.0 2.9 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4200 PF13863.6 EAN32749.1 - 2.1 8.8 16.1 1.8 9.0 7.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Csm1_N PF18504.1 EAN32749.1 - 4.1 7.8 19.4 2 8.8 2.9 3.6 2 1 0 3 3 3 0 Csm1 N-terminal domain HALZ PF02183.18 EAN32749.1 - 5.9 7.2 15.2 1.1 9.5 0.1 4.6 4 1 0 4 4 4 0 Homeobox associated leucine zipper LMBR1 PF04791.16 EAN32749.1 - 8.2 5.2 9.6 12 4.7 9.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein NYD-SP28_assoc PF14775.6 EAN32749.1 - 8.3 6.6 7.7 4.3 7.5 0.8 2.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain DNA_topoisoIV PF00521.20 EAN32750.1 - 1.7e-130 435.8 3.6 1.7e-130 435.8 3.6 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EAN32750.1 - 1e-45 155.1 7.5 1e-45 155.1 7.5 3.4 4 0 0 4 4 4 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EAN32750.1 - 6e-23 81.2 5.5 1e-22 80.5 3.0 2.4 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 EAN32750.1 - 2.4e-09 37.7 0.1 1.4e-07 32.0 0.0 3.2 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EAN32750.1 - 8.8e-09 35.5 0.0 3e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 Toprim domain Phage_int_SAM_5 PF13102.6 EAN32751.1 - 0.015 15.7 2.3 0.1 12.9 0.1 3.2 2 0 0 2 2 2 0 Phage integrase SAM-like domain DNA_pol_D_N PF18018.1 EAN32752.1 - 5.1e-30 104.3 0.3 7.7e-30 103.7 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 EAN32752.1 - 5.7e-14 52.0 1.6 1.5e-11 44.1 0.6 3.8 3 1 0 3 3 3 1 DNA polymerase alpha/epsilon subunit B Mito_morph_reg PF14972.6 EAN32752.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator Rootletin PF15035.6 EAN32753.1 - 0.014 15.4 4.4 0.014 15.4 4.4 1.6 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cupin_8 PF13621.6 EAN32754.1 - 2.4e-34 119.2 0.0 3.1e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EAN32754.1 - 1.4e-05 24.8 0.0 5.8e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EAN32754.1 - 0.047 14.1 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Asp_Arg_Hydrox PF05118.15 EAN32754.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase YusW PF14039.6 EAN32755.1 - 0.041 14.4 0.2 0.14 12.7 0.1 2.0 2 0 0 2 2 2 0 YusW-like protein Ribosomal_S8 PF00410.19 EAN32755.1 - 0.043 13.8 0.1 0.46 10.4 0.0 2.2 1 1 1 2 2 2 0 Ribosomal protein S8 7kD_DNA_binding PF02294.18 EAN32755.1 - 0.12 12.5 0.3 0.12 12.5 0.3 1.9 2 0 0 2 2 2 0 7kD DNA-binding domain DUF406 PF04175.12 EAN32755.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF406) RAMP4 PF06624.12 EAN32756.1 - 2.1 8.5 7.0 4.7 7.4 0.0 2.1 1 1 1 2 2 2 0 Ribosome associated membrane protein RAMP4 TMEM43 PF07787.12 EAN32757.1 - 8.6e-12 45.0 0.3 4.6e-11 42.6 0.0 1.8 1 1 1 2 2 2 1 Transmembrane protein 43 DAGK_acc PF00609.19 EAN32758.1 - 4.3e-16 59.7 0.0 2e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 EAN32758.1 - 1.5e-10 40.8 0.0 5.2e-09 35.8 0.0 2.9 2 1 0 2 2 2 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EAN32758.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase TarS_C1 PF18674.1 EAN32758.1 - 0.048 13.6 0.1 0.072 13.0 0.1 1.2 1 0 0 1 1 1 0 TarS beta-glycosyltransferase C-terminal domain 1 TPR_14 PF13428.6 EAN32759.1 - 7.9e-19 66.8 0.0 0.0011 19.6 0.1 9.2 7 2 4 11 11 10 4 Tetratricopeptide repeat HAT PF02184.16 EAN32759.1 - 4.8e-15 55.2 38.9 0.00043 20.2 0.5 9.9 12 0 0 12 12 11 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 EAN32759.1 - 3.5e-14 53.1 0.0 2.4e-06 28.0 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAN32759.1 - 2.3e-10 40.1 10.5 0.26 11.7 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat Suf PF05843.14 EAN32759.1 - 5.8e-10 39.6 33.1 0.00018 21.6 1.5 5.9 2 2 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_8 PF13181.6 EAN32759.1 - 3.6e-09 36.1 9.0 1.1 9.6 0.0 8.4 8 1 0 8 8 8 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EAN32759.1 - 2.4e-08 34.0 18.6 0.0076 16.2 3.1 6.3 5 1 1 6 6 6 4 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 EAN32759.1 - 1.3e-07 31.2 14.1 0.17 12.1 0.0 8.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAN32759.1 - 1.6e-06 28.4 0.4 54 4.7 0.0 7.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 EAN32759.1 - 1.6e-05 24.2 7.0 0.036 13.3 0.4 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAN32759.1 - 2e-05 24.3 3.4 1.4 9.1 0.0 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EAN32759.1 - 0.00032 19.9 18.7 0.0021 17.2 0.2 5.3 3 2 1 4 4 4 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 EAN32759.1 - 0.00038 21.0 0.1 1.3 9.7 0.0 3.5 3 1 1 4 4 2 2 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EAN32759.1 - 0.00065 19.7 24.7 0.013 15.6 0.4 7.1 5 2 3 8 8 8 3 U3 small nucleolar RNA-associated protein 6 TPR_9 PF13371.6 EAN32759.1 - 0.0032 17.6 0.6 0.59 10.3 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAN32759.1 - 0.004 17.4 0.5 36 4.7 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAN32759.1 - 0.13 12.5 3.4 3.2 8.0 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 F-box-like_2 PF13013.6 EAN32759.1 - 0.23 11.4 2.4 3.5 7.6 0.5 3.0 2 0 0 2 2 2 0 F-box-like domain TPR_1 PF00515.28 EAN32759.1 - 2.4 8.2 5.7 9.5 6.2 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAN32759.1 - 8.3 6.4 7.1 65 3.6 0.2 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Med14 PF08638.11 EAN32762.1 - 2.8e-07 30.2 1.5 4.5e-07 29.5 1.5 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 SF3b10 PF07189.11 EAN32763.1 - 3.2e-32 110.5 0.1 3.8e-32 110.2 0.1 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) P22_AR_C PF10548.9 EAN32763.1 - 0.12 12.6 0.0 2.5 8.3 0.0 2.1 1 1 1 2 2 2 0 P22AR C-terminal domain RPAP1_N PF08621.10 EAN32765.1 - 0.0067 16.2 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal RRM_occluded PF16842.5 EAN32765.1 - 0.07 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif NDUF_B4 PF07225.12 EAN32765.1 - 0.081 12.8 0.5 0.46 10.4 0.1 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Leo1 PF04004.13 EAN32766.1 - 1.9e-06 27.9 0.4 1.9e-06 27.9 0.4 1.7 2 0 0 2 2 2 1 Leo1-like protein Mod_r PF07200.13 EAN32767.1 - 0.0099 16.0 6.3 0.0099 16.0 6.3 2.2 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein QWRF PF04484.12 EAN32767.1 - 0.023 14.5 0.1 0.023 14.5 0.1 2.6 3 0 0 3 3 3 0 QWRF family BORCS7 PF16088.5 EAN32767.1 - 0.093 13.0 5.2 0.44 10.8 3.0 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF948 PF06103.11 EAN32767.1 - 0.19 12.0 4.0 0.31 11.3 3.5 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 EAN32767.1 - 0.25 11.8 6.8 0.61 10.6 6.8 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 EAN32767.1 - 1 9.5 10.9 0.55 10.4 7.7 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 EAN32767.1 - 1.1 9.5 11.6 0.36 11.1 8.1 1.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 EAN32767.1 - 2.9 8.2 11.7 5.4 7.4 4.4 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EAN32767.1 - 4.7 7.7 9.3 2.8 8.5 5.4 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EAN32767.1 - 5.4 7.1 6.6 3.4 7.7 4.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 EAN32767.1 - 7 6.2 8.5 10 5.6 0.2 2.2 2 0 0 2 2 2 0 fzo-like conserved region RAP PF08373.10 EAN32768.1 - 9.5e-06 25.6 0.0 3.3e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 RAP domain XkdW PF09636.10 EAN32768.1 - 0.022 14.9 0.1 0.28 11.3 0.0 2.4 2 0 0 2 2 2 0 XkdW protein CS PF04969.16 EAN32769.1 - 0.0019 19.2 0.1 0.0027 18.7 0.1 1.3 1 0 0 1 1 1 1 CS domain Ribosomal_S6e PF01092.19 EAN32770.1 - 3.5e-54 182.1 1.2 3.6e-54 182.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e ATP-synt_D PF01813.17 EAN32771.1 - 1.1e-56 191.8 0.7 1.3e-56 191.6 0.7 1.0 1 0 0 1 1 1 1 ATP synthase subunit D MINDY_DUB PF04424.13 EAN32772.1 - 2.7e-14 53.2 0.0 7.8e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 MINDY deubiquitinase DnaJ PF00226.31 EAN32773.1 - 3.2e-20 72.0 0.2 1e-19 70.4 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 EAN32773.1 - 4.2e-20 72.0 2.8 3.9e-19 68.8 2.8 2.1 1 1 0 1 1 1 1 Sec63 Brl domain Xylo_C PF12529.8 EAN32773.1 - 0.0092 15.6 0.1 0.028 14.0 0.1 1.8 1 0 0 1 1 1 1 Xylosyltransferase C terminal TMF_DNA_bd PF12329.8 EAN32774.1 - 0.0014 18.6 0.4 0.0014 18.6 0.4 5.1 3 1 2 5 5 5 2 TATA element modulatory factor 1 DNA binding DUF3037 PF11236.8 EAN32774.1 - 0.076 13.5 6.0 10 6.6 0.5 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3037) SlyX PF04102.12 EAN32774.1 - 1 10.0 12.3 6.2 7.5 0.1 3.9 2 1 1 3 3 3 0 SlyX HrpB7 PF09486.10 EAN32774.1 - 1.5 9.2 5.6 7.4 6.9 0.2 3.0 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Lectin_N PF03954.14 EAN32774.1 - 3.4 7.4 16.9 0.21 11.3 0.8 3.7 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain UNC-79 PF14776.6 EAN32775.1 - 0.00084 18.2 0.1 0.012 14.5 0.0 2.1 1 1 0 2 2 2 1 Cation-channel complex subunit UNC-79 MitMem_reg PF13012.6 EAN32775.1 - 0.12 12.9 2.4 5.4 7.5 0.1 2.9 2 1 1 3 3 3 0 Maintenance of mitochondrial structure and function MnmE_helical PF12631.7 EAN32775.1 - 0.18 11.9 0.9 0.99 9.5 0.1 1.9 1 1 1 2 2 2 0 MnmE helical domain Solute_trans_a PF03619.16 EAN32776.1 - 6.4e-51 173.4 23.3 8.1e-51 173.1 23.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha cNMP_binding PF00027.29 EAN32777.1 - 3.9e-39 132.6 0.0 4.7e-25 87.5 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 EAN32777.1 - 0.099 12.4 0.2 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Cupin domain T6PP_N PF18572.1 EAN32778.1 - 0.089 12.6 0.2 0.75 9.7 0.0 2.4 3 0 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Roughex PF06020.11 EAN32779.1 - 2 7.5 6.2 1.6 7.7 5.4 1.3 1 1 0 1 1 1 0 Drosophila roughex protein AP2 PF00847.20 EAN32780.1 - 1.3e-07 31.7 0.8 2.9e-07 30.6 0.8 1.5 1 0 0 1 1 1 1 AP2 domain DEAD PF00270.29 EAN32781.1 - 2e-39 135.2 0.0 2.3e-38 131.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN32781.1 - 2.1e-24 86.0 0.2 8.2e-24 84.1 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN32781.1 - 3.2e-09 37.0 1.6 8e-08 32.5 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAN32781.1 - 2.5e-05 23.6 0.0 2.5e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DUF4217 PF13959.6 EAN32781.1 - 0.00044 20.4 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 EAN32781.1 - 0.021 15.1 0.0 0.088 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAN32781.1 - 0.045 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain CAF1A PF12253.8 EAN32782.1 - 5.2e-05 23.3 7.8 0.00018 21.6 7.8 1.9 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A PHO4 PF01384.20 EAN32783.1 - 2e-98 329.6 0.7 2.6e-98 329.2 0.7 1.2 1 0 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.10 EAN32783.1 - 0.04 13.7 0.8 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 IclR helix-turn-helix domain TrbC PF04956.13 EAN32783.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.7 3 1 0 3 3 3 0 TrbC/VIRB2 family DUF4677 PF15726.5 EAN32783.1 - 1.7 8.7 4.4 3.8 7.6 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) Eno-Rase_FAD_bd PF07055.12 EAN32785.1 - 0.0083 16.5 0.3 0.037 14.5 0.0 2.0 1 1 1 2 2 2 1 Enoyl reductase FAD binding domain Tup_N PF08581.10 EAN32785.1 - 0.018 15.3 2.4 0.053 13.8 0.1 2.3 1 1 1 2 2 2 0 Tup N-terminal Lipoprotein_20 PF13942.6 EAN32785.1 - 0.024 14.6 1.5 0.028 14.4 1.5 1.1 1 0 0 1 1 1 0 YfhG lipoprotein Pox_A_type_inc PF04508.12 EAN32785.1 - 0.26 11.2 3.5 0.3 11.0 0.3 2.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF3763 PF12592.8 EAN32785.1 - 0.35 11.0 2.9 0.8 9.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3763) cNMP_binding PF00027.29 EAN32786.1 - 5.9e-18 64.7 0.1 8.5e-08 32.2 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain HSA PF07529.13 EAN32787.1 - 0.0004 20.7 0.2 0.00095 19.4 0.2 1.7 1 0 0 1 1 1 1 HSA Peptidase_C54 PF03416.19 EAN32788.1 - 1.3e-18 67.4 0.0 1.6e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 EAN32788.1 - 0.0056 16.2 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 DUF3819 PF12842.7 EAN32789.1 - 8.7e-31 106.8 0.1 2e-30 105.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Not1 PF04054.15 EAN32789.1 - 5.5e-30 104.5 8.5 1.2e-29 103.3 8.5 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EAN32789.1 - 7e-28 97.6 4.6 3.1e-27 95.4 4.6 2.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DKCLD PF08068.12 EAN32791.1 - 9.6e-32 108.9 0.5 3.3e-31 107.1 0.4 1.9 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 EAN32791.1 - 1.5e-24 87.1 0.2 1.6e-21 77.2 0.2 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EAN32791.1 - 2.9e-21 75.4 0.2 5.3e-21 74.5 0.2 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EAN32791.1 - 2.5e-19 69.0 2.4 5.8e-19 67.8 2.4 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EAN32791.1 - 0.025 14.9 0.0 0.1 12.9 0.0 2.1 1 1 1 2 2 2 0 UPF0113 PUA domain PseudoU_synth_2 PF00849.22 EAN32791.1 - 0.052 13.6 0.1 0.09 12.9 0.1 1.4 1 0 0 1 1 1 0 RNA pseudouridylate synthase DEAD PF00270.29 EAN32792.1 - 6.5e-17 61.9 0.0 1.7e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN32792.1 - 1.9e-13 50.7 0.2 5.6e-12 46.0 0.2 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EAN32792.1 - 5.5e-10 39.8 0.3 2e-09 38.0 0.3 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 EAN32792.1 - 5.9e-08 32.9 0.0 1.9e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DTC PF18102.1 EAN32793.1 - 8.4e-27 93.9 0.0 1.6e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Deltex C-terminal domain zf-RING_2 PF13639.6 EAN32793.1 - 6.5e-06 26.4 7.3 6.5e-06 26.4 7.3 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAN32793.1 - 0.0021 17.9 8.1 0.0046 16.8 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN32793.1 - 0.0024 17.8 6.5 0.0056 16.7 6.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAN32793.1 - 0.0093 15.9 7.9 0.025 14.5 7.9 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EAN32793.1 - 0.0098 15.7 8.0 0.0098 15.7 8.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EAN32793.1 - 0.074 13.1 3.0 0.17 12.0 2.7 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EAN32793.1 - 0.14 11.9 7.4 0.35 10.7 7.4 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 EAN32793.1 - 0.95 9.8 10.2 0.45 10.9 6.4 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain PHD PF00628.29 EAN32793.1 - 2.8 7.9 7.3 4.9 7.1 7.3 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 EAN32793.1 - 4 7.1 9.6 1.8 8.2 6.8 2.0 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Di19 PF05605.12 EAN32793.1 - 4.1 7.8 7.2 8.7 6.7 0.1 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding SKIP_SNW PF02731.15 EAN32794.1 - 3.3e-64 215.4 6.0 3.3e-64 215.4 6.0 2.8 3 0 0 3 3 3 1 SKIP/SNW domain GBP PF02263.19 EAN32795.1 - 1.7e-12 47.2 0.2 5.2e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EAN32795.1 - 0.088 12.9 0.1 0.35 11.0 0.1 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase DnaJ-X PF14308.6 EAN32797.1 - 7.8e-41 139.8 0.5 1.3e-40 139.1 0.5 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EAN32797.1 - 1.1e-24 86.3 1.8 2.6e-24 85.1 1.8 1.7 1 0 0 1 1 1 1 DnaJ domain DUF410 PF04190.13 EAN32797.1 - 0.029 14.2 1.4 0.15 11.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF410) Glyco_tran_28_C PF04101.16 EAN32798.1 - 5.9e-21 75.2 0.0 7.8e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PBP_like_2 PF12849.7 EAN32798.1 - 0.1 12.2 0.0 0.73 9.4 0.0 2.0 1 1 0 1 1 1 0 PBP superfamily domain UPF0114 PF03350.16 EAN32798.1 - 0.14 12.3 0.1 6.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 LUC7 PF03194.15 EAN32799.1 - 3.3e-70 236.6 8.0 3.3e-70 236.6 8.0 1.5 2 0 0 2 2 2 1 LUC7 N_terminus DSHCT PF08148.12 EAN32800.1 - 2.4e-42 144.4 0.8 9.1e-42 142.5 0.0 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 EAN32800.1 - 1.3e-41 143.3 7.1 2.4e-41 142.5 7.1 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EAN32800.1 - 5.9e-18 65.2 0.1 6.4e-17 61.9 0.0 2.9 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN32800.1 - 1.1e-07 32.1 0.2 9.1e-07 29.2 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN32800.1 - 0.00013 22.1 0.7 0.00048 20.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAN32800.1 - 0.0049 17.1 1.0 0.71 10.1 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EAN32800.1 - 0.022 14.8 0.4 2.5 8.1 0.0 4.3 4 2 1 5 5 5 0 AAA domain DUF4268 PF14088.6 EAN32800.1 - 0.3 11.0 2.2 4.7 7.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4268) Exonuc_VII_L PF02601.15 EAN32800.1 - 1 8.9 4.5 1.1 8.7 1.0 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Sec2p PF06428.11 EAN32800.1 - 4.1 7.4 6.7 2.2 8.3 0.6 3.0 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Swi5 PF07061.11 EAN32800.1 - 6.5 6.9 6.4 9 6.5 0.0 3.6 3 0 0 3 3 3 0 Swi5 MAT1 PF06391.13 EAN32803.1 - 5.9e-12 45.8 12.5 9.6e-12 45.2 12.5 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_2 PF13639.6 EAN32803.1 - 6.5e-06 26.4 6.4 1.5e-05 25.2 6.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAN32803.1 - 0.00016 21.4 7.3 0.00041 20.1 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAN32803.1 - 0.00098 19.0 8.7 0.0019 18.1 8.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAN32803.1 - 0.0012 18.8 4.4 0.0022 18.0 3.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_5 PF17121.5 EAN32803.1 - 0.0058 16.5 5.0 0.012 15.5 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PDDEXK_10 PF07788.11 EAN32803.1 - 0.056 13.4 2.4 0.061 13.3 0.2 2.1 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily zf-ANAPC11 PF12861.7 EAN32803.1 - 0.084 12.9 5.0 0.16 12.1 5.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EAN32803.1 - 0.23 11.2 7.9 0.1 12.4 1.6 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 EAN32803.1 - 2 8.3 13.6 0.15 12.0 7.7 2.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAN32803.1 - 2.4 8.1 14.0 2.8 7.9 7.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 C2 PF00168.30 EAN32804.1 - 0.0016 18.7 0.0 0.0019 18.5 0.0 1.1 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 EAN32805.1 - 2.8e-17 62.9 0.3 0.0059 16.9 0.0 5.1 5 0 0 5 5 5 4 C2 domain Ferlin_C PF16165.5 EAN32805.1 - 0.0032 17.4 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Ferlin C-terminus E1-E2_ATPase PF00122.20 EAN32807.1 - 1.2e-50 171.6 1.3 1.2e-50 171.6 1.3 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAN32807.1 - 2.9e-47 160.7 3.2 2.9e-47 160.7 3.2 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EAN32807.1 - 1.6e-19 71.1 0.0 5.5e-07 30.1 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAN32807.1 - 3.5e-09 36.6 0.0 1.9e-08 34.2 0.0 2.3 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EAN32807.1 - 8.2e-09 35.0 0.0 2.4e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAN32807.1 - 0.0017 18.2 1.6 0.0017 18.2 1.6 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAN32807.1 - 0.0021 18.5 0.0 0.052 13.9 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PAP_central PF04928.17 EAN32807.1 - 0.025 13.6 0.2 0.2 10.6 0.2 2.2 1 1 0 1 1 1 0 Poly(A) polymerase central domain Virul_fac_BrkB PF03631.15 EAN32807.1 - 1.1 8.8 5.7 0.3 10.7 0.5 2.5 3 0 0 3 3 3 0 Virulence factor BrkB TRM PF02005.16 EAN32808.1 - 9.2e-95 318.0 0.0 9.3e-57 192.9 0.0 3.2 2 1 1 3 3 3 3 N2,N2-dimethylguanosine tRNA methyltransferase DUF2067 PF09840.9 EAN32808.1 - 0.00015 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) DUF2387 PF09526.10 EAN32809.1 - 0.15 12.2 0.3 0.74 10.0 0.0 2.3 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) FAINT PF04385.15 EAN32810.1 - 1.6e-07 31.3 12.7 1.1e-05 25.4 2.7 3.6 3 0 0 3 3 3 2 Domain of unknown function, DUF529 Stevor PF17410.2 EAN32811.1 - 0.1 12.2 0.2 8.5 5.8 0.1 2.5 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF2208 PF09973.9 EAN32812.1 - 0.0025 17.5 3.7 0.0029 17.3 3.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) UFD1 PF03152.14 EAN32813.1 - 7.2e-66 220.9 0.0 9.1e-66 220.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CX9C PF16860.5 EAN32814.1 - 1.5e-07 31.3 11.0 2e-06 27.7 2.7 3.2 1 1 1 3 3 3 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EAN32814.1 - 0.0051 16.9 8.7 0.0081 16.3 0.8 3.1 1 1 2 3 3 3 1 CHCH domain NDUF_B7 PF05676.13 EAN32814.1 - 0.011 15.4 8.9 0.38 10.5 0.9 3.0 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.17 EAN32814.1 - 0.21 11.8 9.6 1.6 9.0 6.9 2.5 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 EAN32814.1 - 0.39 10.8 8.9 0.078 13.0 3.0 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like MCM PF00493.23 EAN32815.1 - 1.8e-88 295.4 0.0 1e-80 270.0 0.0 2.3 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 EAN32815.1 - 7.3e-31 106.6 0.0 1.7e-30 105.4 0.0 1.7 2 0 0 2 2 1 1 MCM OB domain MCM_lid PF17855.1 EAN32815.1 - 8.4e-20 71.0 0.7 2e-19 69.8 0.2 2.0 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_N PF14551.6 EAN32815.1 - 7.4e-09 36.1 0.3 3.8e-08 33.9 0.1 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EAN32815.1 - 2.4e-08 33.6 0.1 1.5e-05 24.5 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAN32815.1 - 1.4e-06 28.4 0.0 4.1e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EAN32815.1 - 1.3e-05 25.0 0.0 4.3e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 EAN32815.1 - 0.0027 18.1 0.0 0.011 16.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAN32815.1 - 0.012 16.0 0.1 0.041 14.3 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_3 PF07726.11 EAN32815.1 - 0.019 14.8 0.0 0.066 13.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4844 PF16133.5 EAN32815.1 - 0.071 13.7 0.2 0.24 12.0 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) MMR_HSR1 PF01926.23 EAN32815.1 - 0.083 13.0 0.0 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase DEK_C PF08766.11 EAN32816.1 - 7.3e-06 25.8 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain 5_3_exonuc_N PF02739.16 EAN32820.1 - 1.2e-30 106.5 0.0 8.1e-25 87.6 0.0 2.4 2 0 0 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 EAN32820.1 - 5.6e-19 68.6 0.5 1.1e-18 67.5 0.0 1.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_lambd_f PF10391.9 EAN32820.1 - 0.0049 16.7 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_2 PF12826.7 EAN32820.1 - 0.016 15.3 0.0 0.096 12.8 0.0 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 EAN32820.1 - 0.047 14.3 0.0 0.094 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain HTH_36 PF13730.6 EAN32820.1 - 0.07 13.1 0.3 0.23 11.5 0.3 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Sel1 PF08238.12 EAN32821.1 - 2.2e-14 53.5 6.7 0.0004 21.0 0.2 6.1 6 0 0 6 6 6 4 Sel1 repeat RRM_1 PF00076.22 EAN32822.1 - 1.5e-14 53.5 0.2 3e-14 52.6 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAN32822.1 - 1.4e-05 24.7 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5603 PF18231.1 EAN32822.1 - 0.098 13.0 0.1 0.15 12.4 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5603) tRNA-synt_1 PF00133.22 EAN32824.1 - 2.7e-74 250.5 6.3 2.4e-48 164.8 3.1 4.5 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EAN32824.1 - 4e-17 62.1 5.5 1.7e-07 30.3 0.0 4.7 5 0 0 5 5 5 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EAN32824.1 - 7.4e-17 61.7 0.0 2.3e-16 60.1 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA CENP_C_N PF15622.6 EAN32824.1 - 0.0031 17.0 0.0 0.01 15.3 0.0 1.8 1 0 0 1 1 1 1 Kinetochore assembly subunit CENP-C N-terminal tRNA-synt_1_2 PF13603.6 EAN32824.1 - 0.025 14.1 0.4 0.21 11.1 0.0 2.3 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 MPC PF03650.13 EAN32825.1 - 1.9e-30 105.2 0.3 4e-30 104.2 0.3 1.5 1 1 0 1 1 1 1 Mitochondrial pyruvate carriers RRM_1 PF00076.22 EAN32827.1 - 6.3e-20 70.8 0.1 1e-19 70.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 EAN32827.1 - 2e-18 66.8 3.0 4.4e-18 65.7 3.0 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_7 PF16367.5 EAN32827.1 - 0.0051 16.9 0.0 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EAN32827.1 - 0.021 14.4 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 EAN32827.1 - 0.24 11.6 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain NAD_binding_1 PF00175.21 EAN32828.1 - 5.3e-12 46.3 0.0 9.1e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EAN32828.1 - 2.3e-05 24.7 0.0 5.7e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EAN32828.1 - 0.12 12.5 0.1 1 9.5 0.1 2.2 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Ras PF00071.22 EAN32829.1 - 6.9e-11 42.0 0.0 5.9e-09 35.7 0.1 2.2 2 0 0 2 2 2 2 Ras family PduV-EutP PF10662.9 EAN32829.1 - 0.00063 19.5 0.0 0.34 10.7 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EAN32829.1 - 0.0051 16.4 0.1 0.7 9.4 0.1 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 EAN32829.1 - 0.14 12.4 0.0 3.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TAFII55_N PF04658.13 EAN32830.1 - 1.7e-22 79.8 0.0 3.3e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region DBR1 PF05011.13 EAN32831.1 - 1.1e-15 58.3 0.2 1.9e-15 57.5 0.2 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EAN32831.1 - 5.4e-09 36.8 1.4 8.8e-09 36.2 0.6 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 EAN32831.1 - 0.00055 19.3 0.0 0.0012 18.2 0.0 1.6 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Metallophos_2 PF12850.7 EAN32831.1 - 0.055 13.7 0.0 0.16 12.1 0.0 2.0 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain SIP1 PF04938.12 EAN32832.1 - 0.0041 16.9 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Nop PF01798.18 EAN32833.1 - 2.8e-80 269.1 0.1 3.9e-80 268.6 0.1 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EAN32833.1 - 7.7e-17 61.4 0.4 2e-16 60.1 0.4 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain SecE PF00584.20 EAN32834.1 - 0.013 15.4 6.6 0.027 14.4 6.6 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex TMEM154 PF15102.6 EAN32834.1 - 0.019 14.8 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family RAMP4 PF06624.12 EAN32834.1 - 0.023 14.7 0.7 0.046 13.8 0.7 1.4 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 DUF4448 PF14610.6 EAN32834.1 - 0.03 14.1 1.2 0.037 13.8 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3119 PF11317.8 EAN32835.1 - 0.035 14.4 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3119) ETRAMP PF09716.10 EAN32836.1 - 0.0023 17.9 0.0 0.0078 16.2 0.0 1.9 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Rax2 PF12768.7 EAN32836.1 - 0.078 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Sulfate_transp PF00916.20 EAN32837.1 - 1.9e-24 86.1 30.3 1.7e-23 83.0 30.3 2.3 1 1 0 1 1 1 1 Sulfate permease family Herpes_U55 PF06501.11 EAN32837.1 - 0.00018 20.4 0.1 0.00032 19.6 0.1 1.3 1 0 0 1 1 1 1 Human herpesvirus U55 protein STAS PF01740.21 EAN32837.1 - 0.0089 15.7 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF21 PF01595.20 EAN32839.1 - 3.5e-34 118.0 3.4 7.1e-34 117.0 3.4 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EAN32839.1 - 0.00018 21.9 0.2 0.67 10.4 0.0 2.7 2 0 0 2 2 2 2 CBS domain Profilin PF00235.19 EAN32840.1 - 3.5e-20 72.6 0.0 4.6e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Profilin Methyltr_RsmB-F PF01189.17 EAN32841.1 - 5.2e-67 225.4 0.0 7.5e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EAN32841.1 - 1.8e-09 38.0 0.0 3.2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EAN32841.1 - 9.4e-05 22.6 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ras PF00071.22 EAN32842.1 - 7e-50 168.8 0.1 8.6e-50 168.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAN32842.1 - 1e-28 100.0 0.0 1.5e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAN32842.1 - 9.6e-17 61.0 0.0 1.3e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAN32842.1 - 7.6e-07 28.9 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAN32842.1 - 0.0005 19.5 0.0 0.00063 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAN32842.1 - 0.001 19.2 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Proteasome PF00227.26 EAN32843.1 - 6.3e-41 140.0 0.2 1.8e-20 73.2 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit RRM_9 PF18444.1 EAN32843.1 - 0.082 12.8 0.0 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif Rhomboid PF01694.22 EAN32845.1 - 2.2e-23 82.9 14.0 2.2e-23 82.9 14.0 1.6 2 0 0 2 2 2 1 Rhomboid family NPL4 PF05021.15 EAN32846.1 - 3.8e-32 111.9 0.1 6.8e-30 104.5 0.1 3.0 1 1 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.8 EAN32846.1 - 8.2e-27 93.5 1.3 8.2e-27 93.5 1.3 1.9 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 zf-NPL4 PF05020.15 EAN32846.1 - 7.3e-05 23.0 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region ubiquitin PF00240.23 EAN32846.1 - 0.00024 20.8 0.5 0.00065 19.4 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin family SRR PF07709.11 EAN32847.1 - 0.00046 20.1 11.1 11 6.9 0.2 4.9 4 0 0 4 4 4 3 Seven Residue Repeat DUF148 PF02520.17 EAN32847.1 - 0.021 14.9 7.2 0.3 11.2 1.3 3.2 2 1 1 3 3 3 0 Domain of unknown function DUF148 DUF5344 PF17279.2 EAN32847.1 - 0.045 14.3 9.1 0.17 12.5 2.3 3.5 2 2 2 4 4 4 0 Family of unknown function (DUF5344) SKA2 PF16740.5 EAN32847.1 - 0.19 11.5 3.3 2.2 8.1 0.3 3.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Cas_Cmr5 PF09701.10 EAN32847.1 - 0.76 10.1 6.1 0.28 11.5 2.4 2.2 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) Tup_N PF08581.10 EAN32847.1 - 0.76 10.1 2.8 1.8 8.9 0.4 2.7 2 2 1 3 3 3 0 Tup N-terminal PhaP_Bmeg PF09602.10 EAN32847.1 - 3.5 7.5 8.4 1.1 9.1 1.8 2.8 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Cytochrom_C_2 PF01322.20 EAN32847.1 - 3.9 8.4 13.5 0.19 12.6 1.6 3.6 1 1 1 3 3 3 0 Cytochrome C' 5_3_exonuc PF01367.20 EAN32847.1 - 4.3 8.0 7.2 1.5 9.5 0.4 3.0 2 1 2 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold Ala_racemase_N PF01168.20 EAN32848.1 - 1.1e-12 48.1 0.0 1.4e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Rhomboid PF01694.22 EAN32850.1 - 8.2e-17 61.6 7.5 8.2e-17 61.6 7.5 1.6 2 0 0 2 2 2 1 Rhomboid family Ribosomal_L4 PF00573.22 EAN32851.1 - 1.8e-39 135.4 0.4 3e-39 134.7 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EAN32851.1 - 0.0015 18.6 0.5 0.0068 16.4 0.2 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Streptin-Immun PF11083.8 EAN32854.1 - 0.032 14.6 0.3 0.12 12.8 0.3 2.0 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein Xpo1 PF08389.12 EAN32855.1 - 0.0001 22.4 6.8 0.0001 22.4 6.8 4.8 3 3 0 3 3 3 2 Exportin 1-like protein RhoGAP PF00620.27 EAN32855.1 - 0.0022 17.9 3.9 1.6 8.5 0.0 3.7 3 0 0 3 3 3 2 RhoGAP domain CRIC_ras_sig PF10534.9 EAN32855.1 - 0.058 13.6 1.8 0.19 11.9 0.6 2.6 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras STAT_alpha PF01017.20 EAN32856.1 - 0.033 14.1 0.7 0.04 13.8 0.7 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain Guanylate_kin PF00625.21 EAN32859.1 - 6.1e-44 149.9 0.0 7.2e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 EAN32859.1 - 9e-05 22.7 0.0 0.0021 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAN32859.1 - 0.00012 22.3 0.0 0.00022 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EAN32859.1 - 0.00068 20.2 0.0 0.00083 19.9 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 EAN32859.1 - 0.0013 19.3 0.1 0.0027 18.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EAN32859.1 - 0.0046 16.4 0.0 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EAN32859.1 - 0.007 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAN32859.1 - 0.01 16.2 0.0 0.017 15.5 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 EAN32859.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 EAN32859.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EAN32859.1 - 0.011 16.0 0.0 0.023 14.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EAN32859.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 EAN32859.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 EAN32859.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 EAN32859.1 - 0.033 14.4 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 EAN32859.1 - 0.037 13.9 0.0 0.066 13.1 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 EAN32859.1 - 0.041 13.6 0.1 0.092 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.6 EAN32859.1 - 0.053 13.9 0.0 0.19 12.1 0.0 1.9 2 1 1 3 3 2 0 AAA domain AAA_23 PF13476.6 EAN32859.1 - 0.063 13.8 0.1 0.063 13.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EAN32859.1 - 0.079 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 EAN32859.1 - 0.079 13.3 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EAN32859.1 - 0.096 12.4 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EAN32859.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 EAN32859.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAN32859.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EAN32859.1 - 0.19 10.7 0.0 0.76 8.8 0.0 1.9 3 0 0 3 3 3 0 Type II/IV secretion system protein PFK PF00365.20 EAN32860.1 - 1.7e-59 201.5 0.0 1.7e-37 129.3 0.0 3.1 4 0 0 4 4 4 2 Phosphofructokinase FAINT PF04385.15 EAN32861.1 - 1.5e-06 28.1 20.7 1.3e-05 25.1 4.6 5.0 4 2 1 5 5 5 3 Domain of unknown function, DUF529 SSP160 PF06933.11 EAN32862.1 - 3 5.9 12.0 0.11 10.6 2.7 2.2 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Pro_isomerase PF00160.21 EAN32863.1 - 5e-46 156.8 0.0 8.5e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 EAN32863.1 - 1.3e-06 28.0 0.4 4.6e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Rtf2 RING-finger zf-Nse PF11789.8 EAN32863.1 - 0.014 15.2 0.1 0.086 12.7 0.1 2.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SSP160 PF06933.11 EAN32864.1 - 9.9 4.2 9.4 15 3.6 9.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF2666 PF10869.8 EAN32865.1 - 0.023 14.9 0.2 0.075 13.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) CK_II_beta PF01214.18 EAN32867.1 - 3.5e-60 202.9 0.0 4.4e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Zn_Tnp_IS1 PF03811.13 EAN32867.1 - 0.097 12.4 2.4 0.15 11.9 0.2 2.2 2 0 0 2 2 2 0 InsA N-terminal domain PseudoU_synth_2 PF00849.22 EAN32869.1 - 0.0032 17.6 0.0 0.0051 16.9 0.0 1.3 1 1 0 1 1 1 1 RNA pseudouridylate synthase RNase_H2_suC PF08615.11 EAN32870.1 - 1.9e-07 31.3 0.0 6.7e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TLD PF07534.16 EAN32873.1 - 8e-34 116.8 2.9 2.3e-33 115.4 2.9 1.8 1 0 0 1 1 1 1 TLD Lig_chan PF00060.26 EAN32874.1 - 8.8 6.2 8.1 3.9 7.3 0.3 3.3 3 0 0 3 3 3 0 Ligand-gated ion channel Zip PF02535.22 EAN32875.1 - 0.009 15.3 2.2 0.009 15.3 2.2 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter PPP4R2 PF09184.11 EAN32877.1 - 0.016 14.8 14.4 0.098 12.2 14.4 2.6 1 1 0 1 1 1 0 PPP4R2 ATG16 PF08614.11 EAN32877.1 - 0.059 13.6 0.6 0.44 10.8 0.4 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) BACK PF07707.15 EAN32877.1 - 0.076 13.1 0.2 5.9 7.0 0.0 2.3 2 0 0 2 2 2 0 BTB And C-terminal Kelch RAP PF08373.10 EAN32878.1 - 0.0076 16.3 2.9 0.011 15.9 0.4 2.7 2 0 0 2 2 2 1 RAP domain Myb_DNA-bind_3 PF12776.7 EAN32878.1 - 0.043 14.8 0.4 0.56 11.2 0.1 3.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAN32878.1 - 0.25 11.6 2.0 0.81 10.0 0.1 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Nop PF01798.18 EAN32879.1 - 5.7e-60 202.7 0.4 5.7e-60 202.7 0.4 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EAN32879.1 - 5.9e-32 111.1 1.5 7.7e-32 110.7 0.5 1.7 2 0 0 2 2 2 1 Prp31 C terminal domain ubiquitin PF00240.23 EAN32880.1 - 1.7e-21 75.8 0.1 1.8e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAN32880.1 - 6.9e-14 51.4 0.1 7.6e-14 51.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EAN32880.1 - 7.4e-05 22.8 0.0 0.00027 21.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAN32880.1 - 0.0005 20.6 0.0 0.00058 20.4 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 EAN32880.1 - 0.0007 20.0 0.1 0.0021 18.5 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EAN32880.1 - 0.011 16.1 0.0 0.012 16.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Pro_isomerase PF00160.21 EAN32881.1 - 1.7e-44 151.9 0.0 2.8e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MNNL PF07657.13 EAN32881.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 N terminus of Notch ligand CDC45 PF02724.14 EAN32881.1 - 10 4.3 13.5 13 3.9 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein LRR_4 PF12799.7 EAN32882.1 - 6.6e-07 29.6 49.3 0.0014 19.0 5.9 6.6 5 2 1 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAN32882.1 - 1.1e-05 25.1 26.7 0.012 15.3 10.4 4.8 3 2 1 4 4 4 3 Leucine rich repeat Ubiquitin_2 PF14560.6 EAN32882.1 - 1.9e-05 25.0 0.2 6.6e-05 23.3 0.2 2.0 1 0 0 1 1 1 1 Ubiquitin-like domain PCNA_N PF00705.18 EAN32883.1 - 3.6e-25 88.1 1.1 5.6e-25 87.5 0.7 1.6 1 1 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EAN32883.1 - 2e-18 66.8 0.2 3e-17 63.0 0.1 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EAN32883.1 - 1.4e-07 31.3 0.4 1.1e-06 28.2 0.4 2.1 1 1 0 1 1 1 1 Rad9 Thioredoxin PF00085.20 EAN32885.1 - 3.6e-26 91.2 0.0 5.1e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAN32885.1 - 3.5e-05 24.2 0.2 0.00062 20.2 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EAN32885.1 - 0.00031 20.2 0.1 0.00063 19.2 0.1 1.6 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 EAN32885.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EAN32885.1 - 0.0031 17.4 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 EAN32885.1 - 0.0043 17.3 0.0 0.1 13.0 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EAN32885.1 - 0.021 15.0 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 EAN32885.1 - 0.052 13.6 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain ERp29_N PF07912.13 EAN32885.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 ERp29, N-terminal domain AhpC-TSA PF00578.21 EAN32885.1 - 0.16 11.9 0.1 0.34 10.8 0.1 1.5 1 1 0 1 1 1 0 AhpC/TSA family MMR_HSR1 PF01926.23 EAN32886.1 - 6.1e-08 32.7 2.0 3.3e-07 30.4 1.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAN32886.1 - 2.2e-05 24.4 1.0 8.4e-05 22.5 1.0 2.0 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 EAN32886.1 - 0.002 17.7 0.6 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAN32886.1 - 0.01 15.2 0.1 0.033 13.6 0.1 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 EAN32886.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EAN32886.1 - 0.034 14.6 0.5 0.1 13.1 0.0 2.0 2 0 0 2 2 1 0 ABC transporter Dynamin_N PF00350.23 EAN32886.1 - 0.035 14.2 4.7 0.35 10.9 0.1 3.8 3 1 1 4 4 4 0 Dynamin family T2SSE PF00437.20 EAN32886.1 - 0.036 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.9 EAN32886.1 - 0.038 13.8 0.4 1.2 8.9 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EAN32886.1 - 0.05 13.9 0.1 0.16 12.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 EAN32886.1 - 0.059 13.8 0.3 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 EAN32886.1 - 0.063 12.8 0.2 0.16 11.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Arf PF00025.21 EAN32886.1 - 0.079 12.4 0.3 8.5 5.8 0.1 2.6 1 1 1 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.6 EAN32886.1 - 0.19 12.1 0.0 0.53 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 EAN32886.1 - 0.32 10.9 0.0 0.32 10.9 0.0 2.3 2 1 1 3 3 2 0 ATPase domain predominantly from Archaea PRCC PF10253.9 EAN32887.1 - 1.8e-13 51.8 3.3 2.3e-13 51.5 3.3 1.4 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Mito_carr PF00153.27 EAN32888.1 - 7.7e-59 195.6 0.4 1.3e-23 82.7 0.1 3.1 1 1 2 3 3 3 3 Mitochondrial carrier protein DUF4203 PF13886.6 EAN32888.1 - 0.031 13.9 0.5 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) 14-3-3 PF00244.20 EAN32890.1 - 1.1e-98 329.2 9.8 1.2e-98 329.0 9.8 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.6 EAN32890.1 - 0.074 12.5 0.5 0.14 11.6 0.4 1.6 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3106 PF11304.8 EAN32890.1 - 0.71 10.4 3.2 7.5 7.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) TPR_8 PF13181.6 EAN32890.1 - 0.82 10.0 4.7 2.7 8.4 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat FAINT PF04385.15 EAN32891.1 - 5.9e-21 74.3 17.6 2e-06 27.8 1.0 4.3 4 0 0 4 4 4 4 Domain of unknown function, DUF529 Fcf1 PF04900.12 EAN32892.1 - 4e-33 113.8 1.2 6.5e-33 113.1 1.2 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EAN32892.1 - 8.6e-09 35.7 0.6 6.4e-08 32.9 0.6 2.2 1 1 0 1 1 1 1 PIN like domain DUF842 PF05811.13 EAN32893.1 - 3e-25 88.4 15.6 9.9e-25 86.7 15.6 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Bin3 PF06859.12 EAN32893.1 - 0.0054 17.3 0.1 0.015 15.9 0.1 1.7 1 1 1 2 2 2 1 Bicoid-interacting protein 3 (Bin3) DUF745 PF05335.13 EAN32893.1 - 0.042 13.6 1.5 0.067 12.9 1.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Baculo_PEP_C PF04513.12 EAN32893.1 - 0.042 13.9 0.9 0.084 12.9 0.3 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 EAN32893.1 - 0.045 13.1 2.5 0.54 9.6 0.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding OmpH PF03938.14 EAN32893.1 - 0.069 13.5 0.4 0.57 10.5 0.2 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CLZ PF16526.5 EAN32893.1 - 0.076 13.4 0.4 12 6.4 0.1 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Methyltransf_25 PF13649.6 EAN32893.1 - 0.14 12.9 0.2 29 5.5 0.0 2.4 1 1 2 3 3 3 0 Methyltransferase domain DUF725 PF05267.12 EAN32893.1 - 0.57 10.2 13.8 0.44 10.5 12.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF725) Histone PF00125.24 EAN32894.1 - 3.8e-18 66.1 0.0 4.8e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAN32894.1 - 1.5e-11 43.8 0.1 2.8e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAN32894.1 - 0.00011 22.4 0.0 0.00015 22.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hairpins PF04877.12 EAN32894.1 - 0.53 9.9 4.5 0.66 9.6 4.5 1.1 1 0 0 1 1 1 0 HrpZ TRAPP PF04051.16 EAN32895.1 - 1.5e-31 109.1 0.2 1.8e-31 108.8 0.2 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DEAD PF00270.29 EAN32896.1 - 3.2e-44 150.8 0.1 4.3e-44 150.4 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN32896.1 - 2.1e-27 95.6 0.4 6.9e-27 94.0 0.3 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EAN32896.1 - 0.0065 15.7 0.1 0.01 15.0 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EAN32896.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit zf-RING_2 PF13639.6 EAN32898.1 - 1.3e-12 47.8 7.7 1.3e-12 47.8 7.7 3.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAN32898.1 - 1.5e-10 40.7 6.1 1.5e-10 40.7 6.1 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAN32898.1 - 1.9e-10 40.3 2.2 1.3e-09 37.6 2.2 2.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EAN32898.1 - 2.5e-08 34.1 4.5 2.5e-08 34.1 4.5 3.5 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAN32898.1 - 3.2e-07 30.1 7.1 3.2e-07 30.1 7.1 3.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN32898.1 - 5.4e-07 29.5 1.7 5.4e-07 29.5 1.7 3.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAN32898.1 - 2e-06 27.6 6.3 2e-06 27.6 6.3 2.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EAN32898.1 - 0.00042 20.1 4.0 0.002 17.9 4.0 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TSP_1 PF00090.19 EAN32898.1 - 0.002 18.3 2.1 0.0048 17.1 0.6 2.5 2 0 0 2 2 2 1 Thrombospondin type 1 domain zf-ANAPC11 PF12861.7 EAN32898.1 - 0.0081 16.2 1.7 0.0081 16.2 1.7 3.1 4 0 0 4 4 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EAN32898.1 - 0.048 13.5 9.0 0.016 15.0 4.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 EAN32898.1 - 0.067 13.2 2.4 0.34 11.0 2.4 2.3 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 EAN32898.1 - 0.091 12.4 3.6 0.4 10.3 3.6 2.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EAN32898.1 - 0.3 11.4 5.7 1.7 9.0 5.7 2.5 1 0 0 1 1 1 0 RING-like domain Sporozoite_P67 PF05642.11 EAN32898.1 - 8.2 4.4 9.3 9.4 4.2 0.0 2.9 3 0 0 3 3 3 0 Sporozoite P67 surface antigen BUD22 PF09073.10 EAN32901.1 - 0.15 11.4 11.7 0.21 10.9 11.7 1.2 1 0 0 1 1 1 0 BUD22 Gly-zipper_YMGG PF13441.6 EAN32902.1 - 0.53 10.1 5.5 0.22 11.3 2.5 1.9 2 1 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 EAN32902.1 - 8.6 6.4 10.3 5.4 7.1 6.8 2.4 2 1 0 2 2 2 0 Glycine zipper TSP_1 PF00090.19 EAN32905.1 - 0.0029 17.8 3.9 0.0056 16.9 2.5 2.3 2 0 0 2 2 2 1 Thrombospondin type 1 domain DUF4531 PF15041.6 EAN32905.1 - 0.06 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) PDZ_4 PF17816.1 EAN32905.1 - 0.19 12.1 0.4 0.73 10.3 0.1 2.1 2 0 0 2 2 2 0 PDZ domain NinD PF17466.2 EAN32907.1 - 0.073 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function DnaJ_C PF01556.18 EAN32908.1 - 1.6e-41 141.9 0.2 2.1e-41 141.4 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAN32908.1 - 7.9e-27 93.2 1.0 1.3e-26 92.4 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain ABM PF03992.16 EAN32909.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Leu_Phe_trans PF03588.14 EAN32910.1 - 9.4e-20 70.8 0.3 6.8e-08 32.2 0.0 3.2 2 1 1 3 3 3 3 Leucyl/phenylalanyl-tRNA protein transferase OS-D PF03392.13 EAN32911.1 - 0.3 11.2 0.1 0.3 11.2 0.1 3.3 3 0 0 3 3 3 0 Insect pheromone-binding family, A10/OS-D s48_45 PF07422.13 EAN32912.1 - 3.7e-16 59.6 3.2 4.8e-10 40.0 0.0 4.1 4 1 0 4 4 4 2 Sexual stage antigen s48/45 domain Pkinase PF00069.25 EAN32913.1 - 1e-38 133.2 0.0 2.2e-38 132.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32913.1 - 1.4e-14 54.0 0.0 3.8e-14 52.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAN32913.1 - 0.00042 19.7 0.0 0.02 14.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like KH_8 PF17903.1 EAN32914.1 - 3.4e-32 110.4 0.0 3.4e-32 110.4 0.0 2.0 3 0 0 3 3 3 1 Krr1 KH1 domain KH_1 PF00013.29 EAN32914.1 - 0.0051 16.6 0.3 0.011 15.5 0.3 1.6 1 0 0 1 1 1 1 KH domain Syntaxin PF00804.25 EAN32915.1 - 0.013 15.2 3.3 0.24 11.0 0.0 2.5 1 1 1 2 2 2 0 Syntaxin NPV_P10 PF05531.12 EAN32915.1 - 0.046 14.2 5.2 0.24 11.9 0.1 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.11 EAN32915.1 - 0.056 13.2 4.5 0.27 11.0 0.0 2.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 CorA PF01544.18 EAN32915.1 - 0.11 11.8 5.8 0.069 12.4 3.2 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Yuri_gagarin PF15934.5 EAN32915.1 - 0.17 11.7 6.7 2.9 7.7 3.3 2.2 1 1 1 2 2 2 0 Yuri gagarin TMF_TATA_bd PF12325.8 EAN32915.1 - 0.23 11.7 4.4 4.6 7.5 3.2 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 EAN32915.1 - 4.8 7.3 7.8 12 6.1 0.5 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ribosomal_L22 PF00237.19 EAN32916.1 - 3.6e-12 46.4 0.1 7.4e-12 45.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Na_H_Exchanger PF00999.21 EAN32917.1 - 5.3e-31 107.8 39.2 7.2e-31 107.3 39.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NAPRTase_N PF17767.1 EAN32917.1 - 0.18 12.2 1.7 0.48 10.8 0.4 2.3 3 0 0 3 3 3 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF3342 PF11822.8 EAN32918.1 - 0.023 14.9 2.2 0.028 14.6 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3342) SF3A2 PF16835.5 EAN32919.1 - 7.6e-32 109.6 0.0 1.3e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EAN32919.1 - 1.7e-06 28.2 1.0 3.4e-06 27.3 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EAN32919.1 - 0.00073 19.5 1.1 0.0013 18.6 1.1 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein FAINT PF04385.15 EAN32920.1 - 6.9e-21 74.1 31.9 1.4e-06 28.2 0.6 4.7 4 1 0 4 4 4 4 Domain of unknown function, DUF529 DnaJ PF00226.31 EAN32921.1 - 3.6e-13 49.4 3.1 5e-13 49.0 0.6 2.5 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 EAN32921.1 - 6e-06 26.2 0.4 0.00064 19.7 0.0 3.5 2 2 1 3 3 3 1 Thioredoxin NTP_transferase PF00483.23 EAN32922.1 - 2.2e-51 174.9 0.0 2.7e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EAN32922.1 - 3.3e-10 40.6 0.0 3.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EAN32922.1 - 2.6e-09 36.4 10.9 1.3e-08 34.2 6.7 3.0 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EAN32922.1 - 0.0039 16.9 9.2 0.0039 16.9 9.2 2.4 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EAN32922.1 - 0.021 13.8 2.5 0.22 10.4 1.4 2.3 2 1 0 2 2 2 0 L-fucokinase CTP_transf_3 PF02348.19 EAN32922.1 - 0.13 12.1 0.6 0.22 11.4 0.1 1.7 2 1 0 2 2 2 0 Cytidylyltransferase UQ_con PF00179.26 EAN32923.1 - 5.3e-21 74.7 0.6 1.1e-20 73.7 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAN32923.1 - 0.00026 20.7 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EAN32923.1 - 0.0083 16.0 0.3 0.016 15.1 0.3 1.6 1 0 0 1 1 1 1 UEV domain MACPF PF01823.19 EAN32924.1 - 4.7e-12 46.4 4.3 9.8e-08 32.3 0.2 2.0 1 1 1 2 2 2 2 MAC/Perforin domain DUF1923 PF09083.10 EAN32924.1 - 0.00027 20.6 0.1 0.0029 17.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1923) Raftlin PF15250.6 EAN32924.1 - 0.032 13.0 0.0 0.039 12.7 0.0 1.0 1 0 0 1 1 1 0 Raftlin Adap_comp_sub PF00928.21 EAN32925.1 - 1.4e-18 67.3 5.5 2.8e-18 66.3 5.5 1.5 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Tudor_FRX1 PF18336.1 EAN32928.1 - 0.67 9.9 2.9 6.7 6.7 0.0 2.8 3 0 0 3 3 3 0 Fragile X mental retardation Tudor domain RNA_pol_A_CTD PF03118.15 EAN32929.1 - 0.012 15.4 0.3 0.025 14.3 0.3 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain DUF1904 PF08921.11 EAN32929.1 - 0.093 13.0 1.1 0.53 10.6 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1904) DUF1279 PF06916.13 EAN32930.1 - 2e-08 34.6 1.2 4.7e-08 33.5 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3395 PF11875.8 EAN32931.1 - 7.3e-17 61.7 0.0 6.1e-16 58.7 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EAN32931.1 - 3.6e-14 52.6 3.4 7.7e-14 51.6 3.4 1.6 1 0 0 1 1 1 1 DnaJ domain FPL PF09758.9 EAN32932.1 - 0.0014 18.7 1.0 0.0014 18.7 1.0 3.5 3 0 0 3 3 3 1 Uncharacterised conserved protein Ribosomal_L27 PF01016.19 EAN32934.1 - 1.8e-11 43.9 0.5 1.7e-10 40.8 0.5 2.0 1 1 0 1 1 1 1 Ribosomal L27 protein Hydrolase_4 PF12146.8 EAN32935.1 - 3.8e-17 62.3 0.0 1.4e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAN32935.1 - 1.4e-15 57.6 0.0 1.6e-11 44.3 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAN32935.1 - 2e-09 38.4 0.0 6.8e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EAN32935.1 - 0.00055 19.7 0.0 2.3 7.8 0.0 3.1 3 0 0 3 3 3 2 Serine hydrolase (FSH1) Ndr PF03096.14 EAN32935.1 - 0.0042 15.8 0.1 0.015 14.1 0.1 1.9 1 1 0 1 1 1 1 Ndr family DUF1057 PF06342.12 EAN32935.1 - 0.02 13.9 0.0 0.065 12.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.10 EAN32935.1 - 0.024 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF5600 PF18150.1 EAN32936.1 - 0.086 13.4 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5600) Choline_kinase PF01633.20 EAN32938.1 - 1.2e-33 116.5 1.2 1.6e-33 116.1 1.2 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAN32938.1 - 6.6e-09 36.0 0.0 9.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EAN32938.1 - 0.013 14.9 1.0 0.02 14.2 1.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 EAN32939.1 - 1.6e-31 109.6 0.7 2.2e-31 109.1 0.7 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAN32939.1 - 6.4e-08 32.8 0.0 8.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAN32940.1 - 2.2e-31 109.1 0.4 3.4e-31 108.5 0.4 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAN32940.1 - 1.1e-08 35.3 0.0 1.4e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAN32941.1 - 3.6e-32 111.7 1.1 6.9e-32 110.8 1.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAN32941.1 - 2.6e-07 30.8 0.0 3.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2777 PF10949.8 EAN32941.1 - 0.44 10.2 7.6 0.22 11.2 4.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2777) Choline_kinase PF01633.20 EAN32942.1 - 5.2e-32 111.2 1.4 9.1e-32 110.4 1.4 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAN32942.1 - 5.6e-07 29.7 0.0 7.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAN32943.1 - 8e-30 104.0 1.1 1.3e-29 103.3 1.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAN32943.1 - 1.6e-07 31.5 0.0 2.2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2777 PF10949.8 EAN32943.1 - 0.018 14.7 3.4 0.041 13.5 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) WD40 PF00400.32 EAN32944.1 - 1.3e-16 60.6 14.0 0.0036 18.1 0.6 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN32944.1 - 2.8e-12 46.8 0.0 0.00073 19.8 0.0 4.5 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAN32944.1 - 0.013 15.4 0.1 0.37 10.6 0.0 3.0 1 1 3 4 4 4 0 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EAN32944.1 - 0.083 12.2 0.1 0.48 9.7 0.0 2.3 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Utp13 PF08625.11 EAN32945.1 - 5.5e-22 78.2 6.4 1.1e-21 77.3 6.4 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 EAN32945.1 - 7.2e-14 52.0 18.8 0.0035 18.1 0.2 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat BBS2_Mid PF14783.6 EAN32945.1 - 0.017 15.2 1.8 1.3 9.1 0.1 4.2 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 EAN32946.1 - 1.4e-11 44.7 2.8 0.0023 18.7 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN32946.1 - 6.1e-06 26.4 0.2 1.9 8.8 0.0 4.0 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 EAN32946.1 - 0.042 13.1 0.2 0.23 10.8 0.0 2.0 1 1 0 2 2 2 0 CPSF A subunit region Pkinase PF00069.25 EAN32947.1 - 1.4e-55 188.5 1.1 6.4e-43 147.0 0.2 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32947.1 - 4.1e-37 127.9 0.0 1e-27 97.1 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAN32947.1 - 7e-05 21.8 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EAN32947.1 - 0.0048 16.5 1.5 0.1 12.2 0.1 2.7 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAN32947.1 - 0.0095 15.3 0.1 0.021 14.2 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAN32947.1 - 0.047 13.0 0.0 0.092 12.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF1985 PF09331.11 EAN32947.1 - 0.13 12.3 1.5 0.21 11.6 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) tRNA-synt_His PF13393.6 EAN32947.1 - 0.16 11.2 0.2 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Snf7 PF03357.21 EAN32948.1 - 3e-17 62.7 15.6 3e-17 62.7 15.6 1.5 1 1 1 2 2 2 1 Snf7 NPC1_N PF16414.5 EAN32948.1 - 0.0064 16.1 0.7 0.0082 15.7 0.7 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Citrate_synt PF00285.21 EAN32949.1 - 9.6e-95 317.7 0.0 1.3e-94 317.2 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain GcpE PF04551.14 EAN32950.1 - 8.6e-154 511.8 0.0 1.8e-153 510.8 0.0 1.5 1 1 0 1 1 1 1 GcpE protein Nnf1 PF03980.14 EAN32950.1 - 0.2 12.0 0.4 0.64 10.4 0.4 1.8 1 0 0 1 1 1 0 Nnf1 Acyltransferase PF01553.21 EAN32951.1 - 3.6e-11 42.8 0.0 7.2e-11 41.8 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase VPS9 PF02204.18 EAN32952.1 - 1.1e-24 86.7 1.0 3.5e-24 85.0 0.5 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain His_kinase PF06580.13 EAN32952.1 - 0.27 11.6 4.5 1 9.7 1.7 3.0 3 0 0 3 3 3 0 Histidine kinase RGCC PF15151.6 EAN32952.1 - 1.3 9.3 4.8 3.8 7.7 0.1 2.6 2 0 0 2 2 2 0 Response gene to complement 32 protein family DUF5344 PF17279.2 EAN32952.1 - 9.2 6.9 11.3 1.5 9.4 2.3 3.4 3 1 1 4 4 4 0 Family of unknown function (DUF5344) CAF1C_H4-bd PF12265.8 EAN32953.1 - 7.7e-13 48.5 0.2 2.8e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EAN32953.1 - 6.6e-12 45.8 16.8 0.005 17.7 3.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN32953.1 - 0.00012 22.3 2.4 0.18 12.1 0.1 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAN32953.1 - 0.022 14.1 0.4 0.044 13.1 0.1 1.6 2 0 0 2 2 2 0 WD40-like domain PX PF00787.24 EAN32954.1 - 2.2e-08 34.0 0.1 5.1e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 PX domain WD40 PF00400.32 EAN32954.1 - 6e-05 23.7 0.1 0.075 13.9 0.1 4.6 4 1 0 4 4 4 1 WD domain, G-beta repeat MFS_1 PF07690.16 EAN32955.1 - 1.8e-06 27.1 33.1 2.4e-06 26.7 27.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EAN32956.1 - 1e-12 47.7 5.7 1e-12 47.7 5.7 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EAN32957.1 - 7.6e-11 41.5 18.6 7.6e-11 41.5 18.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Leader_Erm PF08253.11 EAN32957.1 - 0.15 12.4 2.5 9.9 6.7 0.3 3.3 2 0 0 2 2 2 0 Erm Leader peptide GCP_N_terminal PF17681.1 EAN32958.1 - 7.2e-15 55.4 2.2 3.4e-14 53.2 0.4 2.6 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF535 PF04393.13 EAN32958.1 - 0.091 12.0 1.5 0.11 11.8 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF535) CAF1 PF04857.20 EAN32959.1 - 4.2e-76 256.1 0.8 5.5e-76 255.8 0.8 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 EAN32959.1 - 3e-07 30.4 1.3 8.2e-07 29.0 1.3 1.8 1 0 0 1 1 1 1 RNA binding domain R3H PF01424.22 EAN32959.1 - 1.4e-05 24.9 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 R3H domain DNA_pol_A_exo1 PF01612.20 EAN32959.1 - 0.012 15.3 0.6 0.54 9.9 0.0 3.4 4 0 0 4 4 4 0 3'-5' exonuclease RNase_T PF00929.24 EAN32959.1 - 0.031 14.8 2.4 4.4 7.8 0.1 4.1 5 0 0 5 5 5 0 Exonuclease DUF5320 PF17253.2 EAN32959.1 - 0.037 15.1 0.2 0.094 13.8 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF5595 PF18077.1 EAN32959.1 - 0.067 13.3 1.5 0.3 11.2 1.5 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) TIG_2 PF18020.1 EAN32959.1 - 0.29 11.8 2.1 4.5 8.0 0.1 3.1 3 0 0 3 3 3 0 TIG domain found in plexin DFRP_C PF16543.5 EAN32960.1 - 4e-16 59.3 4.1 4e-16 59.3 4.1 3.7 2 1 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Pfg27 PF09216.10 EAN32960.1 - 0.013 15.3 4.4 0.019 14.8 3.6 1.7 1 1 0 1 1 1 0 Pfg27 PMT2_N PF17987.1 EAN32960.1 - 0.017 15.3 0.2 0.088 13.0 0.0 2.2 3 1 0 3 3 3 0 Phosphoethanolamine N-methyltransferase 2 N-terminal eIF-5_eIF-2B PF01873.17 EAN32961.1 - 1e-35 122.2 0.0 1.5e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-RanBP PF00641.18 EAN32961.1 - 0.06 12.7 1.8 4.4 6.7 0.1 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Ribosomal_L28 PF00830.19 EAN32963.1 - 8.3e-13 48.3 2.1 8.3e-13 48.3 2.1 2.3 3 0 0 3 3 3 1 Ribosomal L28 family GHMP_kinases_C PF08544.13 EAN32964.1 - 0.00018 21.8 0.0 0.0041 17.5 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EAN32964.1 - 0.0022 18.2 0.4 0.0053 17.0 0.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain LPD29 PF18847.1 EAN32964.1 - 0.048 14.6 0.3 0.11 13.5 0.3 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 29 PPR_2 PF13041.6 EAN32965.1 - 0.022 15.0 0.1 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 PPR repeat family ATPase_2 PF01637.18 EAN32966.1 - 1.7e-06 28.1 1.5 1.7e-06 28.1 1.5 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EAN32966.1 - 3.3e-06 27.4 0.0 1e-05 25.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EAN32966.1 - 2.2e-05 24.9 0.8 0.00027 21.4 0.8 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAN32966.1 - 9.9e-05 22.8 0.0 0.00024 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EAN32966.1 - 0.019 15.5 0.1 0.098 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EAN32966.1 - 0.03 13.8 0.3 0.074 12.6 0.3 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Hen1_Lam_C PF18441.1 EAN32966.1 - 0.4 10.5 5.1 4 7.3 0.1 3.1 2 1 0 3 3 3 0 Hen1 La-motif C-terminal domain DUF5121 PF17165.4 EAN32966.1 - 0.6 10.6 2.5 2.6 8.5 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5121) Kinesin PF00225.23 EAN32968.1 - 2.3e-79 266.7 0.6 2.3e-79 266.7 0.6 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EAN32968.1 - 6.1e-16 58.7 2.6 4.6e-15 55.8 0.2 2.6 2 0 0 2 2 2 1 Microtubule binding TatD_DNase PF01026.21 EAN32969.1 - 1.8e-43 148.8 0.0 2.3e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Vac14_Fab1_bd PF12755.7 EAN32971.1 - 5.9e-36 123.0 8.9 5e-32 110.4 1.2 4.3 3 1 1 4 4 4 3 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.8 EAN32971.1 - 1.3e-25 90.1 7.2 1.3e-25 90.1 7.2 2.5 2 1 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.22 EAN32971.1 - 2.5e-06 27.3 0.2 0.16 12.3 0.0 4.3 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 EAN32971.1 - 5e-06 26.9 0.1 0.097 13.2 0.0 4.3 6 0 0 6 6 6 2 HEAT-like repeat Cnd1 PF12717.7 EAN32971.1 - 0.032 14.3 8.6 0.046 13.8 2.6 3.1 1 1 2 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EAN32971.1 - 0.16 12.1 2.8 13 6.0 0.0 3.4 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 EAN32971.1 - 2.8 7.8 6.0 5.9 6.8 1.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) ThiF PF00899.21 EAN32972.1 - 5.1e-85 284.7 0.0 3.2e-62 210.1 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EAN32972.1 - 3.6e-58 197.4 0.1 5.5e-58 196.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EAN32972.1 - 5.8e-24 84.1 0.2 1.4e-23 82.9 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EAN32972.1 - 4e-19 69.1 0.0 1e-18 67.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain Shikimate_DH PF01488.20 EAN32972.1 - 0.0001 22.4 1.0 0.069 13.2 0.5 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase E1_4HB PF16191.5 EAN32972.1 - 0.004 17.3 0.0 0.0099 16.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Pyr_redox_2 PF07992.14 EAN32972.1 - 0.041 13.1 0.0 0.38 10.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAN32972.1 - 0.049 14.2 2.6 1.4 9.5 0.2 3.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EAN32972.1 - 0.098 12.0 0.1 13 5.1 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EAN32972.1 - 0.12 12.6 0.1 3 8.1 0.1 2.9 3 0 0 3 3 3 0 TrkA-N domain ADK PF00406.22 EAN32973.1 - 2.7e-28 98.9 0.0 3.4e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAN32973.1 - 8.3e-21 74.8 0.0 1.3e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAN32973.1 - 2.1e-09 38.0 0.0 3.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAN32973.1 - 8.4e-06 26.0 0.0 4.7e-05 23.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain dNK PF01712.19 EAN32973.1 - 0.0037 17.1 0.1 1.9 8.3 0.1 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase Zeta_toxin PF06414.12 EAN32973.1 - 0.018 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin 6PF2K PF01591.18 EAN32973.1 - 0.034 13.5 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 6-phosphofructo-2-kinase APS_kinase PF01583.20 EAN32973.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.10 EAN32973.1 - 0.051 13.0 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CoaE PF01121.20 EAN32973.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase FAINT PF04385.15 EAN32974.1 - 2.4e-36 123.7 18.1 9.7e-09 35.2 0.1 6.3 6 0 0 6 6 6 6 Domain of unknown function, DUF529 Glyoxal_oxid_N PF07250.11 EAN32975.1 - 0.0066 15.7 0.1 0.0094 15.2 0.1 1.3 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus ABC2_membrane_3 PF12698.7 EAN32975.1 - 0.028 13.5 3.3 0.034 13.2 3.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1629 PF07791.11 EAN32975.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) RabGAP-TBC PF00566.18 EAN32976.1 - 5.6e-26 91.5 1.7 2.5e-24 86.2 1.7 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain EBV-NA1 PF02905.14 EAN32976.1 - 0.021 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain CDC50 PF03381.15 EAN32977.1 - 0.024 14.1 1.7 0.03 13.8 1.7 1.1 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family IFT20 PF14931.6 EAN32977.1 - 0.04 14.1 4.4 0.061 13.5 4.4 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF3342 PF11822.8 EAN32978.1 - 0.013 15.7 0.6 0.019 15.1 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3342) OrfA PF17495.2 EAN32978.1 - 0.032 14.4 0.8 0.058 13.6 0.2 1.7 2 0 0 2 2 2 0 Vpr-like OrfA VGPC1_C PF16799.5 EAN32979.1 - 0.19 11.7 0.0 0.19 11.7 0.0 4.9 4 1 1 5 5 5 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Pkinase PF00069.25 EAN32980.1 - 4.4e-63 213.1 0.0 6.6e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN32980.1 - 5.3e-29 101.3 0.2 1.2e-28 100.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EAN32980.1 - 1.4e-09 38.2 0.6 0.033 14.6 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 EAN32980.1 - 2e-08 33.5 0.3 0.28 11.2 0.0 4.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EAN32980.1 - 6.9e-08 32.2 5.3 0.002 17.9 0.0 4.5 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 EAN32980.1 - 3.2e-07 29.4 3.0 0.018 14.6 0.3 4.1 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 EAN32980.1 - 1.5e-05 24.2 0.2 0.16 11.6 0.1 3.1 2 0 0 2 2 2 2 EF hand APH PF01636.23 EAN32980.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family N-Term_TEN PF11474.8 EAN32980.1 - 0.032 13.9 0.3 0.073 12.7 0.3 1.6 1 0 0 1 1 1 0 Telomerase reverse transcriptase TEN domain FTA2 PF13095.6 EAN32980.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EAN32980.1 - 0.062 12.6 0.0 5.5 6.2 0.0 2.9 3 0 0 3 3 3 0 Kinase-like BCAS2 PF05700.11 EAN32981.1 - 3.5e-15 56.2 4.9 3e-14 53.2 4.9 1.9 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Topoisom_I_N PF02919.15 EAN32981.1 - 0.011 15.3 0.1 0.022 14.3 0.0 1.5 1 1 1 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment UPF0121 PF03661.13 EAN32982.1 - 8.9e-16 58.0 9.9 1.2e-15 57.6 9.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) CMV_1a PF12467.8 EAN32982.1 - 0.039 14.3 0.2 0.039 14.3 0.2 1.7 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family LSM PF01423.22 EAN32983.1 - 5.6e-14 51.6 0.6 7.4e-14 51.2 0.6 1.2 1 0 0 1 1 1 1 LSM domain Sec23_trunk PF04811.15 EAN32984.1 - 5.7e-62 209.4 0.0 9.9e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EAN32984.1 - 3.3e-34 117.5 0.1 7.8e-34 116.3 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EAN32984.1 - 1.1e-21 76.6 0.2 2.7e-21 75.3 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 EAN32984.1 - 2.8e-13 49.6 0.1 5.9e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 EAN32984.1 - 7.1e-11 42.0 1.8 1.6e-10 40.9 1.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Flt3_lig PF02947.14 EAN32986.1 - 0.051 13.8 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 flt3 ligand Serglycin PF04360.12 EAN32986.1 - 0.087 12.8 2.9 0.22 11.5 2.9 1.6 1 0 0 1 1 1 0 Serglycin MucBP PF06458.12 EAN32986.1 - 0.52 11.4 8.0 6.4 7.9 2.7 4.1 3 0 0 3 3 3 0 MucBP domain FAINT PF04385.15 EAN32987.1 - 5.2e-12 45.7 24.4 0.00011 22.2 1.0 4.2 4 0 0 4 4 4 3 Domain of unknown function, DUF529 DUF4330 PF14221.6 EAN32988.1 - 0.065 13.4 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) DUF5325 PF17259.2 EAN32988.1 - 0.081 12.8 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5325) Actin PF00022.19 EAN32990.1 - 2.2e-77 260.4 0.0 8e-77 258.5 0.0 1.8 1 1 0 1 1 1 1 Actin DUF4359 PF14271.6 EAN32990.1 - 0.031 15.0 0.6 0.071 13.9 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4359) HSP70 PF00012.20 EAN32990.1 - 0.12 10.6 0.0 0.16 10.1 0.0 1.3 1 0 0 1 1 1 0 Hsp70 protein MreB_Mbl PF06723.13 EAN32990.1 - 0.17 10.7 0.0 0.45 9.3 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein PP-binding PF00550.25 EAN32991.1 - 4.6e-09 36.5 0.0 6.2e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EAN32991.1 - 0.0038 17.4 0.3 0.0076 16.5 0.3 1.5 1 1 0 1 1 1 1 Acyl-carrier Hemagglutinin PF00509.18 EAN32991.1 - 0.14 10.5 0.1 0.16 10.3 0.1 1.0 1 0 0 1 1 1 0 Haemagglutinin NGP1NT PF08153.12 EAN32992.1 - 1.1e-33 116.1 1.0 2.2e-33 115.2 1.0 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EAN32992.1 - 2.1e-16 60.0 0.1 8.9e-14 51.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EAN32992.1 - 1e-06 28.4 0.1 9e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAN32992.1 - 7.2e-06 26.0 0.0 2.2e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EAN32992.1 - 0.00047 19.7 0.1 0.73 9.3 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAN32992.1 - 0.0014 18.2 0.4 0.31 10.5 0.1 3.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF3388 PF11868.8 EAN32992.1 - 0.035 13.4 3.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3388) Dynamin_N PF00350.23 EAN32992.1 - 0.18 11.8 7.4 1.2 9.2 0.1 3.8 3 1 1 4 4 4 0 Dynamin family SHS2_Rpb7-N PF03876.17 EAN32993.1 - 3e-09 37.1 0.0 6.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RRF PF01765.19 EAN32994.1 - 0.018 15.0 0.7 0.084 12.8 0.8 1.7 1 1 1 2 2 2 0 Ribosome recycling factor PBC PF03792.13 EAN32995.1 - 0.042 13.6 0.1 0.054 13.3 0.1 1.2 1 0 0 1 1 1 0 PBC domain DUF2633 PF11119.8 EAN32995.1 - 0.71 9.8 5.6 1.6 8.7 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF866 PF05907.13 EAN32998.1 - 2.7e-30 105.3 0.1 3e-30 105.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) GNT-I PF03071.15 EAN32998.1 - 0.078 11.7 0.1 0.099 11.4 0.1 1.1 1 0 0 1 1 1 0 GNT-I family IP_trans PF02121.18 EAN32999.1 - 1.8e-30 106.3 0.1 2.8e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein PH PF00169.29 EAN32999.1 - 7.5e-12 45.7 0.8 7.5e-12 45.7 0.8 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 EAN32999.1 - 0.027 14.8 0.2 0.081 13.3 0.2 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain EF-hand_1 PF00036.32 EAN33001.1 - 9.5e-40 131.2 9.7 8.1e-10 37.6 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAN33001.1 - 1.4e-34 118.4 2.3 4.1e-17 62.4 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAN33001.1 - 1.7e-29 101.5 8.9 8.2e-15 54.4 0.7 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EAN33001.1 - 1.7e-29 99.1 5.9 3.8e-09 35.8 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EAN33001.1 - 4.9e-28 95.4 9.1 7.5e-07 28.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EAN33001.1 - 9e-14 51.5 0.0 1e-07 32.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EAN33001.1 - 8.8e-09 35.7 0.1 0.0013 19.1 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EAN33001.1 - 2.5e-08 34.7 0.0 4.2e-05 24.3 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EAN33001.1 - 2.8e-08 33.6 0.8 0.00022 21.1 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EAN33001.1 - 1.1e-06 28.8 2.3 0.0068 16.6 0.3 2.8 2 2 1 3 3 3 2 Dockerin type I domain UPF0154 PF03672.13 EAN33001.1 - 1.9e-05 24.6 0.0 0.02 14.9 0.0 2.7 3 0 0 3 3 2 2 Uncharacterised protein family (UPF0154) TerB PF05099.13 EAN33001.1 - 0.00041 20.3 0.1 0.19 11.7 0.0 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 EAN33001.1 - 0.00062 20.5 0.4 0.57 11.0 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.16 EAN33001.1 - 0.00081 19.7 0.6 0.6 10.5 0.1 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb4 Caleosin PF05042.13 EAN33001.1 - 0.001 19.0 0.4 1 9.2 0.0 3.2 1 1 3 4 4 4 1 Caleosin related protein EFhand_Ca_insen PF08726.10 EAN33001.1 - 0.0021 18.1 0.5 0.011 15.8 0.0 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand DUF5580 PF17743.1 EAN33001.1 - 0.0076 14.8 0.0 0.0079 14.8 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF1103 PF06513.11 EAN33001.1 - 0.011 15.3 0.6 0.012 15.2 0.6 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 EAN33001.1 - 0.032 14.1 0.4 3.2 7.6 0.1 2.3 2 0 0 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 EAN33001.1 - 0.062 13.7 0.2 13 6.2 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain DUF853 PF05872.12 EAN33001.1 - 0.068 11.7 0.1 2.2 6.8 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) YqeY PF09424.10 EAN33001.1 - 0.078 13.0 0.2 1.1 9.3 0.1 2.1 1 1 1 2 2 2 0 Yqey-like protein Fe_hyd_lg_C PF02906.14 EAN33001.1 - 0.14 11.8 0.5 0.38 10.4 0.5 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain HMG_CoA_synt_N PF01154.17 EAN33002.1 - 0.15 12.0 0.2 0.24 11.2 0.2 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal STIMATE PF12400.8 EAN33003.1 - 8.4e-21 74.8 7.8 5.8e-15 56.0 5.3 2.2 2 0 0 2 2 2 2 STIMATE family Ribosomal_L22 PF00237.19 EAN33004.1 - 1.6e-33 115.0 0.0 2.2e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e OST-HTH PF12872.7 EAN33005.1 - 0.00042 20.1 1.3 0.0057 16.4 0.2 3.4 3 1 0 3 3 3 1 OST-HTH/LOTUS domain WIYLD PF10440.9 EAN33005.1 - 0.097 12.5 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain ArgoN PF16486.5 EAN33006.1 - 0.033 14.8 0.1 0.042 14.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain of argonaute IMCp PF12314.8 EAN33008.1 - 3.6e-21 75.2 51.9 9.1e-21 74.0 37.9 4.6 1 1 2 4 4 4 3 Inner membrane complex protein FGGY_N PF00370.21 EAN33009.1 - 7.7e-54 182.8 0.0 1.1e-53 182.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EAN33009.1 - 4.7e-43 147.2 0.0 8.5e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Glyco_tran_WecB PF03808.13 EAN33009.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Ibs_toxin PF13956.6 EAN33010.1 - 0.93 9.6 7.9 2.5 8.2 0.4 2.4 2 0 0 2 2 2 0 Toxin Ibs, type I toxin-antitoxin system Pkinase PF00069.25 EAN33011.1 - 2.2e-59 201.0 0.0 2.2e-58 197.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN33011.1 - 7e-32 110.7 0.0 4.7e-31 108.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAN33011.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DrrA_P4M PF14860.6 EAN33011.1 - 0.15 11.9 1.5 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain DEAD PF00270.29 EAN33012.1 - 3.3e-46 157.3 0.3 6e-46 156.4 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN33012.1 - 1.1e-27 96.6 0.1 4.4e-27 94.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SPOB_a PF14689.6 EAN33012.1 - 0.049 13.4 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF4082 PF13313.6 EAN33012.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) LSM PF01423.22 EAN33013.1 - 1.7e-16 59.6 0.6 2.2e-16 59.3 0.6 1.2 1 0 0 1 1 1 1 LSM domain zf-C3H2C3 PF17122.5 EAN33014.1 - 6.2e-08 32.6 13.6 6.2e-08 32.6 13.6 2.6 3 0 0 3 3 3 1 Zinc-finger zf_C2H2_10 PF18414.1 EAN33014.1 - 0.07 12.7 0.6 0.17 11.4 0.6 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger zf-C3HC4_2 PF13923.6 EAN33014.1 - 0.49 10.3 9.6 0.98 9.3 9.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HR_lesion PF05514.11 EAN33016.1 - 0.068 13.3 2.1 0.15 12.2 1.3 1.9 2 0 0 2 2 2 0 HR-like lesion-inducing MatE PF01554.18 EAN33016.1 - 5.2 6.7 7.0 0.69 9.6 2.6 1.9 2 1 0 2 2 2 0 MatE WD40 PF00400.32 EAN33018.1 - 0.11 13.5 0.3 0.75 10.8 0.1 2.0 2 0 0 2 2 2 0 WD domain, G-beta repeat IF4E PF01652.18 EAN33019.1 - 6.8e-20 71.5 0.2 1.4e-19 70.5 0.2 1.5 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E Ank_4 PF13637.6 EAN33020.1 - 1.1e-25 89.7 1.0 5e-15 55.7 0.1 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAN33020.1 - 2.3e-24 85.8 2.1 2.4e-17 63.3 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EAN33020.1 - 7.2e-23 80.0 2.4 1.7e-07 31.4 0.1 4.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EAN33020.1 - 1e-21 74.6 2.6 2.4e-06 27.4 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAN33020.1 - 1.4e-20 73.0 1.3 8.3e-07 29.2 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) ABC_tran PF00005.27 EAN33021.1 - 3.4e-36 124.8 0.0 6.3e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EAN33021.1 - 3.5e-33 115.4 20.8 4.9e-33 114.9 20.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EAN33021.1 - 1.5e-07 31.1 1.2 8.2e-06 25.4 1.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DEAD PF00270.29 EAN33021.1 - 1.4e-05 25.0 0.2 4.6e-05 23.3 0.2 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.29 EAN33021.1 - 8.5e-05 23.0 0.6 0.0012 19.2 0.6 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAN33021.1 - 0.00054 20.2 0.1 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EAN33021.1 - 0.00084 19.4 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EAN33021.1 - 0.0029 18.1 3.5 0.011 16.2 3.5 2.1 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 EAN33021.1 - 0.0037 17.4 0.3 0.072 13.2 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 EAN33021.1 - 0.0054 16.5 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EAN33021.1 - 0.018 14.6 0.4 0.058 12.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_21 PF13304.6 EAN33021.1 - 0.027 14.3 0.1 0.27 11.0 0.0 2.5 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TniB PF05621.11 EAN33021.1 - 0.031 13.7 0.0 0.84 9.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 EAN33021.1 - 0.032 14.6 0.0 0.06 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 EAN33021.1 - 0.038 14.0 0.1 0.12 12.4 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ISK_Channel PF02060.15 EAN33021.1 - 0.042 13.6 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Slow voltage-gated potassium channel IstB_IS21 PF01695.17 EAN33021.1 - 0.048 13.4 0.0 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 EAN33021.1 - 0.071 12.9 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EAN33021.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein WD40 PF00400.32 EAN33022.1 - 5.9e-10 39.6 9.1 0.0039 18.0 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN33022.1 - 0.0016 18.7 2.6 1.4 9.3 0.1 4.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3552 PF12072.8 EAN33024.1 - 1.8e-06 27.5 23.8 3.2e-06 26.7 13.9 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.15 EAN33024.1 - 0.019 14.5 12.0 0.029 14.0 12.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF390 PF04094.14 EAN33024.1 - 0.037 12.4 0.4 0.045 12.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) APG6_N PF17675.1 EAN33024.1 - 0.38 11.3 31.2 0.19 12.3 28.4 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 EAN33024.1 - 0.43 9.9 7.9 0.6 9.4 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EAN33024.1 - 0.76 8.6 23.6 1.6 7.6 21.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.6 EAN33024.1 - 3.3 8.1 30.6 0.26 11.7 8.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.19 EAN33024.1 - 3.4 5.5 11.3 4 5.2 11.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF745 PF05335.13 EAN33024.1 - 3.6 7.3 10.0 0.92 9.2 6.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Atg14 PF10186.9 EAN33024.1 - 4.9 6.1 18.9 6.6 5.7 18.5 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EAN33024.1 - 9 5.4 14.5 1.1 8.5 9.6 1.8 1 1 0 1 1 1 0 TMPIT-like protein DUF641 PF04859.12 EAN33024.1 - 9.7 6.5 20.4 17 5.8 8.2 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Glycos_transf_2 PF00535.26 EAN33025.1 - 2.8e-28 98.9 0.4 3.1e-18 66.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EAN33025.1 - 3.9e-06 26.9 0.0 0.0023 17.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EAN33025.1 - 9.9e-05 21.9 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 EAN33025.1 - 0.0022 17.5 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DUF3827 PF12877.7 EAN33025.1 - 0.056 11.8 0.6 0.075 11.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) OTU PF02338.19 EAN33026.1 - 3.1e-08 34.2 1.3 1.8e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EAN33026.1 - 0.00086 18.8 0.6 0.019 14.5 0.6 2.3 1 1 0 1 1 1 1 Peptidase C65 Otubain DUF2203 PF09969.9 EAN33026.1 - 0.026 15.3 0.9 0.042 14.6 0.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) T2SSM PF04612.12 EAN33026.1 - 0.055 13.5 0.2 0.076 13.1 0.2 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M FlxA PF14282.6 EAN33026.1 - 0.22 11.5 9.8 0.52 10.3 9.8 1.6 2 0 0 2 2 2 0 FlxA-like protein ACR_tran PF00873.19 EAN33026.1 - 0.29 8.7 0.3 0.33 8.6 0.3 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family EELM2 PF15863.5 EAN33027.1 - 2.7e-70 236.0 11.2 8.6e-70 234.3 11.2 1.8 1 1 0 1 1 1 1 Extended EGL-27 and MTA1 homology domain Methyltransf_16 PF10294.9 EAN33028.1 - 5.4e-27 94.6 0.2 1.1e-26 93.6 0.2 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Ank_2 PF12796.7 EAN33028.1 - 1.1e-10 42.0 0.8 1.1e-08 35.6 0.5 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAN33028.1 - 8.7e-09 35.5 0.9 1.7e-07 31.3 0.8 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAN33028.1 - 2.6e-08 34.2 0.2 0.00035 21.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAN33028.1 - 1.1e-07 31.5 0.3 0.0021 18.4 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EAN33028.1 - 2.3e-05 24.6 0.1 0.21 12.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat MTS PF05175.14 EAN33028.1 - 0.0015 18.1 0.0 0.003 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EAN33028.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF16 PF01519.16 EAN33029.1 - 0.002 18.6 5.1 0.16 12.4 2.1 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF16 UPF0242 PF06785.11 EAN33029.1 - 0.005 17.0 5.7 0.03 14.4 1.7 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 EAN33029.1 - 0.0064 16.3 4.1 0.14 12.0 2.9 2.7 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase XhlA PF10779.9 EAN33029.1 - 0.0078 16.4 7.2 0.17 12.1 1.7 2.3 2 0 0 2 2 2 1 Haemolysin XhlA LXG PF04740.12 EAN33029.1 - 0.011 15.5 3.2 1.8 8.3 0.7 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily BLOC1_2 PF10046.9 EAN33029.1 - 0.012 15.9 5.5 0.18 12.1 1.3 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 EAN33029.1 - 0.013 16.0 3.8 0.018 15.5 3.8 1.1 1 0 0 1 1 1 0 Fez1 LPP PF04728.13 EAN33029.1 - 0.014 15.7 2.9 0.26 11.7 0.1 2.8 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DivIC PF04977.15 EAN33029.1 - 0.018 14.8 1.7 0.018 14.8 1.7 1.8 2 0 0 2 2 2 0 Septum formation initiator PHM7_cyt PF14703.6 EAN33029.1 - 0.022 15.0 1.5 0.03 14.6 1.5 1.3 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter ABC_tran_CTD PF16326.5 EAN33029.1 - 0.03 14.6 6.1 1.1 9.5 4.5 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain JAKMIP_CC3 PF16034.5 EAN33029.1 - 0.055 13.4 6.8 0.16 11.9 6.8 1.7 1 1 0 1 1 1 0 JAKMIP CC3 domain NPV_P10 PF05531.12 EAN33029.1 - 0.063 13.8 1.0 4 8.0 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2802 PF10975.8 EAN33029.1 - 0.064 13.4 1.3 0.45 10.7 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) ING PF12998.7 EAN33029.1 - 0.069 13.7 10.4 0.082 13.5 7.8 2.2 2 1 0 2 2 1 0 Inhibitor of growth proteins N-terminal histone-binding CLZ PF16526.5 EAN33029.1 - 0.072 13.5 4.3 1.1 9.7 1.3 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Translin PF01997.16 EAN33029.1 - 0.09 12.7 5.1 1.2 9.1 1.8 2.1 1 1 0 2 2 2 0 Translin family DUF5082 PF16888.5 EAN33029.1 - 0.13 12.5 7.4 2.8 8.2 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) BRI3BP PF14965.6 EAN33029.1 - 0.14 11.7 0.7 0.35 10.3 0.2 1.9 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Occludin_ELL PF07303.13 EAN33029.1 - 0.14 12.9 6.7 3.9 8.2 2.3 2.2 1 1 1 2 2 2 0 Occludin homology domain Uds1 PF15456.6 EAN33029.1 - 0.15 12.2 3.7 1.8 8.7 3.8 2.2 1 1 1 2 2 2 0 Up-regulated During Septation BST2 PF16716.5 EAN33029.1 - 0.2 12.3 6.5 0.14 12.8 3.7 1.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 HSBP1 PF06825.12 EAN33029.1 - 0.21 11.5 2.6 1.4 8.8 0.7 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Streptin-Immun PF11083.8 EAN33029.1 - 0.23 11.9 6.2 1.7 9.1 0.3 2.4 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Swi5 PF07061.11 EAN33029.1 - 0.24 11.5 5.1 1.4 9.0 1.7 2.3 2 0 0 2 2 2 0 Swi5 Fib_alpha PF08702.10 EAN33029.1 - 0.32 11.2 4.1 8 6.6 1.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Med21 PF11221.8 EAN33029.1 - 0.36 11.1 6.9 0.54 10.5 4.5 2.0 2 0 0 2 2 2 0 Subunit 21 of Mediator complex SlyX PF04102.12 EAN33029.1 - 0.36 11.5 6.2 1.7 9.3 3.5 2.3 2 0 0 2 2 2 0 SlyX TMF_DNA_bd PF12329.8 EAN33029.1 - 0.51 10.4 11.7 1.9 8.5 5.7 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 EAN33029.1 - 0.77 10.2 9.3 1.8 9.0 1.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4795 PF16043.5 EAN33029.1 - 0.77 9.3 8.0 0.83 9.2 3.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Paralemmin PF03285.15 EAN33029.1 - 3 7.3 6.7 1.2 8.6 2.4 2.0 2 0 0 2 2 2 0 Paralemmin ZapB PF06005.12 EAN33029.1 - 8.4 6.9 21.0 1.3 9.5 0.4 2.9 2 1 2 4 4 3 0 Cell division protein ZapB APG6_N PF17675.1 EAN33030.1 - 0.034 14.7 10.6 0.026 15.0 8.9 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region SOGA PF11365.8 EAN33030.1 - 0.1 13.7 6.5 2.7 9.2 6.5 2.7 1 1 0 1 1 1 0 Protein SOGA Paramyx_P_V_C PF03210.13 EAN33030.1 - 0.22 11.3 1.7 7.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal MRPL52 PF18699.1 EAN33030.1 - 0.28 11.4 1.7 0.89 9.8 0.4 2.4 2 1 0 2 2 2 0 Mitoribosomal protein mL52 tRNA-synt_2 PF00152.20 EAN33031.1 - 2e-75 253.8 3.2 2.3e-64 217.4 0.5 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAN33031.1 - 2.1e-07 30.8 0.0 6e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EAN33031.1 - 0.026 14.0 0.2 0.12 11.9 0.1 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF4611 PF15387.6 EAN33031.1 - 0.1 12.9 2.0 0.38 11.0 2.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Rhomboid_N PF12122.8 EAN33031.1 - 0.1 12.8 0.0 0.42 10.8 0.0 2.0 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease GAF PF01590.26 EAN33032.1 - 1.9e-08 35.0 0.0 0.0025 18.5 0.0 3.0 2 1 0 2 2 2 2 GAF domain GAF_2 PF13185.6 EAN33032.1 - 6.8e-05 23.2 0.0 0.0019 18.5 0.0 2.5 3 0 0 3 3 3 1 GAF domain CtsR_C PF17727.1 EAN33032.1 - 0.095 12.8 1.7 8.4 6.6 0.1 3.5 3 0 0 3 3 3 0 CtsR C-terminal dimerization domain PAS_8 PF13188.7 EAN33032.1 - 0.11 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 PAS domain CPSF_A PF03178.15 EAN33033.1 - 5.7e-13 48.9 7.6 3.5e-10 39.7 0.7 3.0 4 0 0 4 4 4 2 CPSF A subunit region Tfb5 PF06331.12 EAN33033.1 - 0.57 10.2 2.8 20 5.3 0.2 3.0 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 eRF1_2 PF03464.15 EAN33034.1 - 1.1e-45 155.1 0.0 2.2e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EAN33034.1 - 6.4e-34 116.8 0.1 1.5e-33 115.7 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EAN33034.1 - 8.9e-19 67.8 0.0 1.8e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EAN33034.1 - 9.9e-09 35.6 0.0 2.7e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EAN33034.1 - 1.9e-08 34.6 0.0 2.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF5643 PF18705.1 EAN33034.1 - 0.033 14.2 0.8 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5643) HTH_16 PF12645.7 EAN33036.1 - 0.0055 16.7 0.1 0.058 13.5 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain DUF4116 PF13475.6 EAN33036.1 - 0.93 9.3 8.5 0.099 12.4 0.6 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4116) HSP70 PF00012.20 EAN33037.1 - 2.3e-267 888.1 10.5 2.7e-267 887.9 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAN33037.1 - 3.6e-16 58.9 3.5 6e-15 54.9 0.7 2.6 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EAN33037.1 - 0.00023 21.0 0.0 0.00058 19.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EAN33037.1 - 0.009 16.4 2.8 6.2 7.3 0.1 3.6 3 2 0 3 3 3 2 Cell division protein FtsA Syntaxin-6_N PF09177.11 EAN33037.1 - 1.1 9.8 8.5 1.5 9.4 6.2 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF261 PF03196.13 EAN33038.1 - 0.26 11.4 2.3 0.28 11.3 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF261 Bromo_TP_like PF17027.5 EAN33039.1 - 0.0023 18.0 0.1 0.0044 17.2 0.1 1.4 1 0 0 1 1 1 1 Histone-fold protein SUB1_ProdP9 PF18213.1 EAN33040.1 - 0.036 13.9 4.4 1.4 8.8 0.3 2.3 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 FAINT PF04385.15 EAN33042.1 - 2.2e-08 34.0 13.9 0.046 13.8 1.1 6.1 5 2 0 5 5 5 3 Domain of unknown function, DUF529 DUF4097 PF13349.6 EAN33042.1 - 0.011 15.0 0.1 0.1 11.9 0.2 2.1 1 1 1 2 2 2 0 Putative adhesin Vma12 PF11712.8 EAN33043.1 - 8.6 6.4 8.1 47 4.0 0.2 3.5 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase FAINT PF04385.15 EAN33044.1 - 6.1e-05 23.0 36.3 0.17 11.9 0.5 9.2 9 0 0 9 9 9 4 Domain of unknown function, DUF529 Toxin_24 PF08094.11 EAN33044.1 - 0.013 15.3 1.8 12 5.8 0.1 3.2 3 0 0 3 3 3 0 Conotoxin TVIIA/GS family WWE PF02825.20 EAN33044.1 - 0.25 11.9 6.4 84 3.9 0.0 5.2 5 0 0 5 5 5 0 WWE domain DUF3024 PF11225.8 EAN33044.1 - 0.61 10.4 12.1 5.9 7.2 0.5 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3024) FAINT PF04385.15 EAN33045.1 - 4.3e-12 45.9 50.2 1.6e-06 28.0 2.7 9.3 10 0 0 10 10 10 5 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33046.1 - 6e-18 64.7 69.5 4.1e-05 23.5 4.1 12.9 12 1 0 12 12 12 7 Domain of unknown function, DUF529 RSS_P20 PF11757.8 EAN33046.1 - 0.0048 17.3 0.8 0.058 13.8 0.4 3.0 2 0 0 2 2 2 1 Suppressor of RNA silencing P21-like N-terminal domain FAINT PF04385.15 EAN33047.1 - 3e-20 72.1 8.8 0.00084 19.3 1.8 7.0 6 0 0 6 6 6 6 Domain of unknown function, DUF529 ANAPC4_WD40 PF12894.7 EAN33048.1 - 4.7e-07 30.0 0.0 0.00033 20.9 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 EAN33048.1 - 0.12 12.3 0.2 1.5 8.8 0.0 2.7 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal RNA_pol_A_bac PF01000.26 EAN33050.1 - 1.3e-27 96.4 0.0 3.4e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EAN33050.1 - 2.8e-18 65.1 0.0 4.2e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Inhibitor_I29 PF08246.12 EAN33050.1 - 0.68 10.4 3.9 1.5 9.3 3.9 1.5 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) eIF-1a PF01176.19 EAN33051.1 - 1.2e-21 76.2 0.0 1.7e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PCI PF01399.27 EAN33052.1 - 4.5e-11 43.2 4.0 4.5e-11 43.2 4.0 2.3 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EAN33052.1 - 4.3e-10 39.5 4.3 1.8e-09 37.6 4.3 2.1 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Brr6_like_C_C PF10104.9 EAN33053.1 - 4.1e-29 101.0 12.4 6.9e-29 100.3 12.4 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Baculo_11_kDa PF06143.11 EAN33053.1 - 0.0086 15.6 10.4 0.25 10.9 0.4 2.5 2 0 0 2 2 2 2 Baculovirus 11 kDa family 7TM_GPCR_Srd PF10317.9 EAN33053.1 - 0.017 14.3 2.3 0.017 14.3 2.3 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd PMT_4TMC PF16192.5 EAN33053.1 - 0.079 12.5 3.8 0.94 9.0 0.0 2.2 1 1 1 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase EphA2_TM PF14575.6 EAN33053.1 - 0.088 13.7 0.6 24 5.9 0.3 2.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4181 PF13789.6 EAN33053.1 - 1.7 8.9 14.0 2.2 8.6 5.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Sigma_reg_N PF13800.6 EAN33053.1 - 2.3 8.6 15.3 3.9 7.8 2.0 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal OAD_gamma PF04277.13 EAN33053.1 - 2.5 8.7 6.2 9.5 6.9 0.9 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Mid2 PF04478.12 EAN33054.1 - 0.0089 15.9 0.1 0.023 14.5 0.1 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DNA_topoisoIV PF00521.20 EAN33055.1 - 3.7e-110 368.8 15.2 1.7e-109 366.6 15.2 2.0 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 EAN33055.1 - 0.078 12.5 2.8 0.33 10.4 0.0 3.4 4 0 0 4 4 4 0 DNA gyrase C-terminal domain, beta-propeller PhoLip_ATPase_C PF16212.5 EAN33056.1 - 3.4e-41 141.7 21.7 3.4e-41 141.7 21.7 3.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAN33056.1 - 3.9e-12 45.7 3.0 1.4e-11 43.9 3.0 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EAN33056.1 - 2.4e-11 44.3 0.0 0.0021 18.4 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EAN33056.1 - 5.9e-08 32.4 3.4 0.00011 21.8 0.0 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 EAN33056.1 - 1.1e-05 25.5 0.0 3.3e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAN33056.1 - 0.0078 16.0 0.1 0.0078 16.0 0.1 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Prok-RING_4 PF14447.6 EAN33058.1 - 2.3 8.2 4.5 0.6 10.0 0.9 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Ribosomal_L12 PF00542.19 EAN33059.1 - 6.2e-19 68.1 9.1 5.9e-16 58.6 4.2 2.9 3 0 0 3 3 3 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EAN33059.1 - 0.007 16.0 0.3 0.007 16.0 0.3 2.1 3 0 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Mononeg_mRNAcap PF14318.6 EAN33059.1 - 0.035 13.4 0.1 0.076 12.3 0.0 1.4 2 0 0 2 2 2 0 Mononegavirales mRNA-capping region V Salp15 PF12115.8 EAN33060.1 - 0.019 15.4 0.9 0.084 13.3 0.9 2.1 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DHHC PF01529.20 EAN33061.1 - 2.6e-35 121.4 16.5 2.6e-35 121.4 16.5 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase FA_desaturase PF00487.24 EAN33061.1 - 4.6 7.0 8.3 0.71 9.6 1.6 2.0 2 0 0 2 2 2 0 Fatty acid desaturase FAINT PF04385.15 EAN33062.1 - 4.1e-13 49.2 11.7 0.00092 19.2 0.8 4.5 4 1 0 4 4 4 3 Domain of unknown function, DUF529 DUF3389 PF11869.8 EAN33063.1 - 0.058 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3389) Toast_rack_N PF17115.5 EAN33063.1 - 0.12 12.7 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of toast_rack, DUF2154 Ribosomal_S5 PF00333.20 EAN33064.1 - 1.8e-27 95.1 0.9 3.6e-27 94.1 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EAN33064.1 - 1.2e-22 79.2 0.0 2e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain CRAL_TRIO PF00650.20 EAN33065.1 - 2.6e-28 98.7 0.2 3.9e-28 98.2 0.2 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAN33065.1 - 9.6e-05 22.5 1.0 0.00021 21.4 1.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EAN33065.1 - 0.00041 20.5 0.2 0.00099 19.3 0.2 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain FAINT PF04385.15 EAN33066.1 - 9.7e-61 201.8 96.9 1.5e-07 31.4 6.6 11.6 11 0 0 11 11 11 11 Domain of unknown function, DUF529 NLPC_P60 PF00877.19 EAN33066.1 - 0.0065 16.5 2.4 3.8 7.6 0.1 4.7 6 0 0 6 6 6 1 NlpC/P60 family Isy1 PF06246.12 EAN33067.1 - 1.8e-56 191.5 3.3 2e-56 191.4 3.3 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Cyto_heme_lyase PF01265.17 EAN33068.1 - 8.7e-47 160.1 11.1 4.2e-46 157.9 11.1 1.8 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase FAINT PF04385.15 EAN33069.1 - 5.2e-12 45.7 39.0 8.7e-05 22.5 0.8 7.0 7 0 0 7 7 7 5 Domain of unknown function, DUF529 ASF1_hist_chap PF04729.13 EAN33070.1 - 1.9e-58 196.8 0.1 3e-58 196.1 0.1 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone PI3_PI4_kinase PF00454.27 EAN33071.1 - 1.2e-23 84.2 0.0 5.2e-23 82.1 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EAN33071.1 - 5.5e-06 26.1 0.0 1.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 FATC domain FAINT PF04385.15 EAN33072.1 - 7.7e-12 45.1 60.4 3.2e-06 27.1 0.2 8.4 6 1 2 8 8 8 5 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33073.1 - 7.4e-06 25.9 1.5 0.017 15.2 0.9 2.4 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FHA PF00498.26 EAN33074.1 - 6.4e-18 64.9 0.3 1.1e-17 64.1 0.3 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EAN33074.1 - 6e-07 29.7 0.0 1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FUN14 PF04930.15 EAN33076.1 - 1.6e-10 41.2 0.9 3.3e-10 40.2 0.7 1.6 1 1 0 1 1 1 1 FUN14 family DUF4497 PF14924.6 EAN33076.1 - 0.073 13.5 0.0 0.099 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) BORCS8 PF10167.9 EAN33077.1 - 0.1 12.5 1.2 0.96 9.4 0.2 2.8 2 1 1 3 3 3 0 BLOC-1-related complex sub-unit 8 VHS PF00790.19 EAN33078.1 - 0.033 14.0 0.1 0.08 12.8 0.1 1.6 1 0 0 1 1 1 0 VHS domain zf-CCCH_4 PF18044.1 EAN33080.1 - 6.2e-05 22.7 3.1 6.2e-05 22.7 3.1 2.8 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EAN33080.1 - 0.0003 20.8 14.8 0.022 14.8 2.4 3.8 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 EAN33080.1 - 0.0013 18.6 1.6 0.0013 18.6 1.6 4.2 5 0 0 5 5 5 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EAN33080.1 - 0.0079 16.6 6.6 0.0079 16.6 6.6 3.4 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EAN33080.1 - 5.5 7.7 11.9 12 6.6 2.0 3.8 4 1 0 4 4 4 0 Torus domain VPS13_C PF16909.5 EAN33081.1 - 1.9e-05 24.5 1.1 1.9e-05 24.5 1.1 3.6 3 1 1 4 4 4 1 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EAN33081.1 - 2.9e-05 24.1 0.1 0.00028 21.0 0.0 2.8 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATP_bind_3 PF01171.20 EAN33082.1 - 4.6e-17 62.4 0.0 6.9e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family CTU2 PF10288.9 EAN33082.1 - 0.0014 18.8 0.0 0.0069 16.6 0.0 2.1 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 tRNA_Me_trans PF03054.16 EAN33082.1 - 0.0027 16.6 0.0 0.0054 15.6 0.0 1.6 1 0 0 1 1 1 1 tRNA methyl transferase zn-ribbon_14 PF16503.5 EAN33082.1 - 0.0084 15.6 1.0 0.0084 15.6 1.0 2.8 3 0 0 3 3 3 1 Zinc-ribbon PAPS_reduct PF01507.19 EAN33082.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family NAD_synthase PF02540.17 EAN33082.1 - 0.083 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase VWA_N2 PF16164.5 EAN33082.1 - 0.11 12.7 2.2 0.11 12.6 0.5 1.9 2 0 0 2 2 2 0 VWA N-terminal Ras PF00071.22 EAN33083.1 - 3.6e-57 192.5 0.4 4.3e-57 192.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAN33083.1 - 1.3e-35 122.2 0.2 1.9e-35 121.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAN33083.1 - 6.8e-18 64.7 0.2 9e-18 64.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAN33083.1 - 1.2e-10 41.2 0.1 1.5e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAN33083.1 - 2.9e-07 30.2 0.2 5e-06 26.2 0.1 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAN33083.1 - 7.2e-07 28.8 0.0 1.3e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAN33083.1 - 0.00017 21.6 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAN33083.1 - 0.0009 18.8 0.1 0.0043 16.6 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAN33083.1 - 0.013 15.4 0.1 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EAN33083.1 - 0.02 14.6 0.0 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EAN33083.1 - 0.039 13.4 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Dynamin_N PF00350.23 EAN33083.1 - 0.043 13.9 0.0 0.76 9.8 0.0 2.3 1 1 0 2 2 2 0 Dynamin family AAA_16 PF13191.6 EAN33083.1 - 0.094 13.1 0.0 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TetR_C_16 PF17920.1 EAN33083.1 - 0.1 12.9 0.0 0.43 10.8 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TIC20 PF16166.5 EAN33084.1 - 2.6e-12 46.9 1.6 3.4e-12 46.5 1.6 1.1 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like Ribosomal_L18 PF17135.4 EAN33085.1 - 2e-78 262.1 5.6 2.3e-78 261.9 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EAN33085.1 - 0.025 15.2 0.1 0.062 14.0 0.1 1.8 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A FAINT PF04385.15 EAN33086.1 - 1.9e-80 265.0 128.6 3.5e-08 33.4 3.8 15.7 15 1 0 15 15 15 15 Domain of unknown function, DUF529 Ribosomal_L18A PF01775.17 EAN33087.1 - 1.4e-53 180.1 0.2 1.9e-53 179.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A ATP-synt_C PF00137.21 EAN33088.1 - 8.2e-08 32.5 9.1 1.7e-07 31.5 9.1 1.5 1 0 0 1 1 1 1 ATP synthase subunit C fragilysinNterm PF16376.5 EAN33089.1 - 0.025 14.3 1.4 0.037 13.8 1.4 1.3 1 0 0 1 1 1 0 N-terminal domain of fragilysin MerC PF03203.14 EAN33090.1 - 2.2e-14 53.9 7.0 2.9e-14 53.5 7.0 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein DUF4834 PF16118.5 EAN33090.1 - 0.014 16.3 0.3 0.014 16.3 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) YrhC PF14143.6 EAN33090.1 - 0.58 10.3 3.6 0.34 11.0 1.3 1.8 1 1 1 2 2 2 0 YrhC-like protein DUF5090 PF17009.5 EAN33090.1 - 0.64 10.0 7.6 0.85 9.6 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DUF202 PF02656.15 EAN33090.1 - 1.9 9.0 5.1 14 6.2 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF202) RRM_1 PF00076.22 EAN33091.1 - 1e-32 111.8 0.2 5.4e-15 55.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAN33091.1 - 1.1e-07 31.7 0.0 0.00016 21.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EAN33091.1 - 8.6e-07 29.0 0.4 0.012 15.6 0.1 3.0 2 1 0 2 2 2 2 Limkain b1 RRM_3 PF08777.11 EAN33091.1 - 0.0011 18.9 0.0 0.098 12.7 0.0 3.0 2 0 0 2 2 2 1 RNA binding motif PHM7_cyt PF14703.6 EAN33091.1 - 0.0063 16.8 0.2 0.0063 16.8 0.2 3.6 3 1 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter DUF4325 PF14213.6 EAN33092.1 - 0.079 12.7 0.4 0.53 10.0 0.1 2.2 2 0 0 2 2 2 0 STAS-like domain of unknown function (DUF4325) TTL PF03133.15 EAN33094.1 - 1.5e-41 142.5 0.7 4.7e-41 140.8 0.7 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EAN33094.1 - 9.8e-10 38.1 0.0 5.1e-05 22.6 0.0 3.2 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EAN33094.1 - 2e-05 24.0 0.0 0.078 12.2 0.0 2.5 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Ribosomal_L27e PF01777.18 EAN33094.1 - 0.046 14.1 2.1 0.37 11.2 0.4 2.6 2 0 0 2 2 2 0 Ribosomal L27e protein family Prenyltrans PF00432.21 EAN33095.1 - 1.7e-32 110.8 8.2 2e-08 33.8 0.1 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Tantalus PF15386.6 EAN33095.1 - 0.13 12.3 0.3 0.32 11.1 0.3 1.6 1 0 0 1 1 1 0 Drosophila Tantalus-like EF-hand_1 PF00036.32 EAN33097.1 - 0.0016 17.9 9.5 0.016 14.7 2.3 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EAN33097.1 - 0.0027 18.1 11.4 0.2 12.1 0.6 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EAN33097.1 - 0.037 14.0 8.1 0.19 11.7 1.5 3.4 2 1 1 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 EAN33097.1 - 0.11 12.4 10.6 0.51 10.2 2.0 3.6 3 1 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 EAN33097.1 - 0.3 10.7 7.7 0.033 13.7 2.4 2.3 2 0 0 2 2 2 0 EF hand PITH PF06201.13 EAN33098.1 - 8.7e-23 81.2 0.0 1.1e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain PPR_2 PF13041.6 EAN33102.1 - 6.8e-28 96.6 15.9 8.1e-11 41.9 0.1 7.7 4 1 4 8 8 8 6 PPR repeat family PPR PF01535.20 EAN33102.1 - 1e-17 63.0 15.8 0.00057 20.0 0.0 7.2 7 0 0 7 7 7 4 PPR repeat PPR_3 PF13812.6 EAN33102.1 - 6.3e-15 55.0 16.4 0.0013 18.7 0.2 6.2 5 1 1 6 6 6 4 Pentatricopeptide repeat domain PPR_long PF17177.4 EAN33102.1 - 2.2e-12 46.8 3.6 2.2e-06 27.2 0.7 3.1 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EAN33102.1 - 2.7e-10 39.7 11.8 0.0061 16.2 0.0 6.0 7 0 0 7 7 7 3 PPR repeat TPR_19 PF14559.6 EAN33102.1 - 0.013 16.0 0.0 4.6 7.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Phage_ABA_S PF18066.1 EAN33102.1 - 0.19 12.5 0.2 52 4.6 0.0 3.3 2 1 2 4 4 4 0 Phage ABA sandwich domain FAINT PF04385.15 EAN33103.1 - 9.3e-19 67.3 34.0 7.3e-06 26.0 10.1 5.2 4 2 1 5 5 5 4 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33104.1 - 1.1e-07 31.8 20.3 1.1e-05 25.4 3.7 3.9 5 0 0 5 5 5 2 Domain of unknown function, DUF529 KCT2 PF17818.1 EAN33104.1 - 0.16 12.0 8.2 0.26 11.4 8.2 1.2 1 0 0 1 1 1 0 Keratinocyte-associated gene product DUF5640 PF18692.1 EAN33104.1 - 2.9 8.0 8.3 0.24 11.5 1.5 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5640) RRM_1 PF00076.22 EAN33105.1 - 0.0002 21.1 0.0 0.00041 20.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UCH PF00443.29 EAN33106.1 - 2.3e-26 92.9 0.2 2.7e-26 92.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EAN33106.1 - 6e-10 39.3 5.2 6e-10 39.3 5.2 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Ndc1_Nup PF09531.10 EAN33106.1 - 2.2 6.8 6.4 3.2 6.3 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup OmpH PF03938.14 EAN33109.1 - 0.036 14.4 7.5 0.053 13.9 7.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RecQ_Zn_bind PF16124.5 EAN33109.1 - 0.15 12.8 4.3 0.35 11.6 1.2 2.5 2 1 0 2 2 2 0 RecQ zinc-binding RE_AlwI PF09491.10 EAN33109.1 - 0.16 10.7 13.5 2.5 6.8 13.4 2.0 1 1 1 2 2 2 0 AlwI restriction endonuclease LMBR1 PF04791.16 EAN33109.1 - 3.9 6.3 5.4 4.4 6.1 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Curto_V3 PF07436.11 EAN33110.1 - 0.012 16.0 2.6 0.019 15.4 0.5 2.3 1 1 1 2 2 2 0 Curtovirus V3 protein Sec20 PF03908.13 EAN33110.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.8 2 1 1 3 3 3 0 Sec20 CxC4 PF18717.1 EAN33110.1 - 0.32 10.9 2.9 9 6.1 0.7 2.2 1 1 1 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases CTP_transf_like PF01467.26 EAN33111.1 - 3.5e-51 173.2 1.2 5.2e-27 94.8 0.3 2.4 2 1 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 EAN33111.1 - 0.024 14.5 0.5 0.51 10.2 0.1 2.8 3 0 0 3 3 3 0 FAD synthetase WW PF00397.26 EAN33112.1 - 2.7e-18 65.7 19.8 5.6e-11 42.3 3.0 3.5 3 0 0 3 3 3 2 WW domain FF PF01846.19 EAN33112.1 - 2.8e-13 49.8 6.5 2.1e-10 40.6 0.3 4.0 4 0 0 4 4 4 2 FF domain Glyco_hyd_101C PF17451.2 EAN33112.1 - 0.13 12.6 12.8 1.7 8.9 0.1 3.7 2 2 2 4 4 4 0 Glycosyl hydrolase 101 beta sandwich domain SNAP PF14938.6 EAN33113.1 - 3.6e-49 167.7 2.1 4.3e-49 167.5 2.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EAN33113.1 - 0.00038 20.7 0.7 0.063 13.6 0.1 1.7 1 1 1 2 2 2 2 Tetratricopeptide repeat MraZ PF02381.18 EAN33113.1 - 0.011 15.7 0.0 0.033 14.2 0.0 1.8 1 1 0 1 1 1 0 MraZ protein, putative antitoxin-like TPR_1 PF00515.28 EAN33113.1 - 0.025 14.4 0.4 0.13 12.2 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAN33113.1 - 0.062 13.6 1.9 1.4 9.3 0.8 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAN33113.1 - 0.11 12.7 0.3 0.41 10.9 0.3 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAN33113.1 - 0.15 12.8 1.5 22 6.0 0.4 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 EAN33114.1 - 8.2e-19 68.1 0.2 8.6e-19 68.0 0.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 EAN33114.1 - 0.00038 20.3 2.5 0.00058 19.8 1.8 1.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAN33114.1 - 0.011 16.0 0.3 0.056 13.7 0.3 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Terpene_synth_C PF03936.16 EAN33114.1 - 0.014 14.8 0.1 0.015 14.7 0.1 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain RPN7 PF10602.9 EAN33114.1 - 0.016 14.9 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TRAPPC9-Trs120 PF08626.11 EAN33114.1 - 0.025 12.0 0.0 0.029 11.7 0.0 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Syja_N PF02383.18 EAN33114.1 - 0.042 13.1 0.1 0.044 13.1 0.1 1.0 1 0 0 1 1 1 0 SacI homology domain TPR_11 PF13414.6 EAN33114.1 - 0.083 12.6 1.7 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 EAN33114.1 - 0.34 10.8 3.7 0.46 10.4 2.9 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat CDP-OH_P_transf PF01066.21 EAN33115.1 - 2.2e-12 47.5 0.0 2.2e-12 47.5 0.0 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GCD14 PF08704.10 EAN33116.1 - 8.4e-57 192.7 0.2 1.7e-56 191.7 0.1 1.5 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 EAN33116.1 - 2.1e-10 40.6 0.0 7e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EAN33116.1 - 1.3e-06 27.8 0.0 5.4e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase PCMT PF01135.19 EAN33116.1 - 2.6e-05 24.1 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EAN33116.1 - 0.00095 19.8 0.0 0.0019 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EAN33116.1 - 0.0028 18.6 0.0 0.0046 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EAN33116.1 - 0.0035 16.8 0.0 0.0074 15.8 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EAN33116.1 - 0.016 14.7 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 EAN33116.1 - 0.019 14.8 0.0 0.058 13.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 EAN33116.1 - 0.034 13.3 0.0 0.067 12.3 0.0 1.4 1 1 0 1 1 1 0 Fibrillarin PrmA PF06325.13 EAN33116.1 - 0.044 13.2 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EAN33116.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-binding PF00249.31 EAN33117.1 - 5.9e-16 58.4 0.2 1.2e-06 28.6 0.0 3.9 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAN33117.1 - 5.1e-15 55.5 0.1 6.6e-06 26.3 0.0 4.2 3 1 1 4 4 4 3 Myb-like DNA-binding domain Bunya_NS-S PF01104.17 EAN33117.1 - 0.58 10.0 3.0 1.5 8.7 0.2 2.9 3 0 0 3 3 3 0 Bunyavirus non-structural protein NS-s Pkinase PF00069.25 EAN33118.1 - 7.1e-08 32.1 0.0 8.1e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN33118.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAN33118.1 - 0.0039 16.6 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EAN33118.1 - 0.035 13.1 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 EAN33118.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Arf PF00025.21 EAN33120.1 - 2.5e-12 46.6 0.0 4.3e-11 42.6 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAN33120.1 - 2.1e-05 24.0 0.1 0.00043 19.8 0.1 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAN33120.1 - 0.00045 20.3 0.2 0.0049 16.9 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EAN33120.1 - 0.024 13.8 0.4 0.16 11.1 0.0 2.1 2 1 0 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 EAN33120.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF815 PF05673.13 EAN33120.1 - 0.093 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 EAN33120.1 - 0.1 12.7 0.2 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAN33120.1 - 0.2 12.0 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SSB PF00436.25 EAN33121.1 - 9.1e-07 28.9 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Single-strand binding protein family DNA_primase_S PF01896.19 EAN33122.1 - 6.7e-51 172.8 1.2 7.8e-50 169.4 1.4 2.0 2 0 0 2 2 2 1 DNA primase small subunit CTP_synth_N PF06418.14 EAN33123.1 - 2e-113 378.1 0.1 2.6e-113 377.7 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EAN33123.1 - 1.1e-37 129.7 0.1 1.8e-35 122.4 0.1 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EAN33123.1 - 7e-05 22.7 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 EAN33123.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PA28_beta PF02252.18 EAN33124.1 - 4.2e-50 169.2 1.1 7.2e-50 168.4 1.1 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 EAN33124.1 - 0.015 15.4 1.5 0.015 15.3 0.1 1.8 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit phage_tail_N PF08400.10 EAN33125.1 - 0.15 12.1 0.5 0.24 11.4 0.5 1.2 1 0 0 1 1 1 0 Prophage tail fibre N-terminal MMR_HSR1 PF01926.23 EAN33127.1 - 9e-13 48.3 0.2 4.3e-12 46.1 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase NOG1 PF06858.14 EAN33127.1 - 2.5e-10 40.0 0.0 9.8e-10 38.1 0.0 2.0 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) FeoB_N PF02421.18 EAN33127.1 - 0.0025 17.4 0.8 0.084 12.4 0.1 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EAN33127.1 - 0.003 17.1 0.2 0.0092 15.5 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAN33127.1 - 0.0065 15.9 0.1 0.017 14.5 0.1 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EAN33127.1 - 0.018 14.9 0.1 0.062 13.2 0.1 1.8 1 1 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 EAN33127.1 - 0.024 14.7 0.1 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Ras PF00071.22 EAN33127.1 - 0.053 13.1 0.9 8.1 6.0 0.0 3.2 3 0 0 3 3 3 0 Ras family CBF PF03914.17 EAN33128.1 - 0.0082 16.2 0.9 0.0082 16.2 0.9 2.2 2 2 0 2 2 2 1 CBF/Mak21 family Holin_SPP1 PF04688.13 EAN33128.1 - 0.029 14.5 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 SPP1 phage holin DUF1348 PF07080.11 EAN33128.1 - 0.064 13.2 1.6 4.2 7.3 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1348) TFIIA PF03153.13 EAN33128.1 - 2.1 8.3 9.3 3.4 7.6 9.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dev_Cell_Death PF10539.9 EAN33130.1 - 0.087 12.7 0.8 0.11 12.4 0.8 1.1 1 0 0 1 1 1 0 Development and cell death domain WD40 PF00400.32 EAN33131.1 - 0.048 14.5 0.2 2.6 9.1 0.1 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF1951 PF09188.10 EAN33131.1 - 0.19 11.7 5.8 0.15 12.1 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1951) ELMO_CED12 PF04727.13 EAN33132.1 - 8.6e-24 84.6 3.9 9.9e-24 84.4 3.4 1.3 1 1 0 1 1 1 1 ELMO/CED-12 family Guanylate_cyc PF00211.20 EAN33133.1 - 2.5e-80 268.4 7.6 2.8e-40 137.9 2.5 3.4 3 1 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 EAN33133.1 - 3.4e-33 115.4 31.5 3.4e-33 115.4 31.5 7.1 6 1 1 7 7 7 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 EAN33133.1 - 2.1e-08 33.9 0.0 2.1e-08 33.9 0.0 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EAN33133.1 - 2.5e-06 27.5 0.1 8.1e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EAN33133.1 - 3.2e-06 27.6 0.0 0.14 12.5 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EAN33133.1 - 0.00043 20.1 0.7 0.00043 20.1 0.7 3.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Spc7 PF08317.11 EAN33135.1 - 0.0093 14.9 2.1 0.013 14.4 2.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Syntaxin PF00804.25 EAN33135.1 - 0.013 15.2 1.1 0.018 14.7 1.1 1.2 1 0 0 1 1 1 0 Syntaxin HJURP_C PF12347.8 EAN33135.1 - 0.026 14.6 0.2 0.066 13.3 0.0 1.8 1 1 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Mod_r PF07200.13 EAN33135.1 - 0.028 14.5 2.0 0.044 13.9 2.0 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein SRR PF07709.11 EAN33135.1 - 0.033 14.5 4.5 0.66 10.6 0.6 3.4 2 1 1 3 3 3 0 Seven Residue Repeat SAM_Exu PF18609.1 EAN33135.1 - 0.095 12.8 2.4 6.2 7.0 0.3 3.0 1 1 2 3 3 3 0 Exuperantia SAM-like domain Fez1 PF06818.15 EAN33135.1 - 0.11 12.9 3.5 0.33 11.4 2.0 1.9 1 1 1 2 2 2 0 Fez1 Urm1 PF09138.11 EAN33137.1 - 8.5e-27 93.4 0.2 1.3e-26 92.8 0.2 1.2 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EAN33137.1 - 0.002 18.7 0.0 0.0039 17.8 0.0 1.6 1 1 0 1 1 1 1 ThiS family S4_2 PF13275.6 EAN33137.1 - 0.044 13.6 0.1 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 S4 domain Metallophos PF00149.28 EAN33138.1 - 1.8e-36 126.5 0.1 2.9e-36 125.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAN33138.1 - 0.0032 17.9 0.2 0.0071 16.8 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EAN33138.1 - 0.022 14.9 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain FAINT PF04385.15 EAN33139.1 - 2.7e-08 33.7 17.2 0.011 15.7 0.0 5.5 4 2 0 4 4 4 4 Domain of unknown function, DUF529 Mucin PF01456.17 EAN33139.1 - 0.0048 16.9 6.8 0.0071 16.3 6.8 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein YTH PF04146.15 EAN33139.1 - 0.14 12.1 1.5 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 YT521-B-like domain FAINT PF04385.15 EAN33140.1 - 5.4e-18 64.8 37.4 8.6e-06 25.7 1.8 7.0 6 0 0 6 6 6 5 Domain of unknown function, DUF529 F-112 PF09645.10 EAN33140.1 - 0.031 14.4 0.2 0.084 13.0 0.2 1.7 1 0 0 1 1 1 0 F-112 protein FAINT PF04385.15 EAN33141.1 - 4.3e-23 81.2 34.9 1.6e-08 34.5 7.1 4.5 4 1 0 4 4 4 4 Domain of unknown function, DUF529 DUF4252 PF14060.6 EAN33141.1 - 0.064 13.2 14.5 0.12 12.2 0.2 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4252) FAINT PF04385.15 EAN33142.1 - 2.5e-07 30.6 0.3 2.5e-07 30.6 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function, DUF529 Mucin PF01456.17 EAN33142.1 - 1 9.3 21.8 0.93 9.5 10.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Gp_dh_C PF02800.20 EAN33143.1 - 3.4e-47 160.0 0.0 4.4e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EAN33143.1 - 7e-29 100.1 0.0 1.6e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EAN33143.1 - 0.0021 18.1 0.0 0.0083 16.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DapB_N PF01113.20 EAN33143.1 - 0.016 15.3 0.2 0.082 13.0 0.1 2.3 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 EAN33143.1 - 0.12 13.0 0.0 0.34 11.6 0.0 1.8 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain V_ATPase_I PF01496.19 EAN33144.1 - 0.0089 14.0 1.9 0.018 13.0 1.9 1.5 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family BLOC1S3 PF15753.5 EAN33144.1 - 0.17 12.0 5.3 0.056 13.6 0.7 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 PIG-F PF06699.11 EAN33145.1 - 0.0042 17.3 13.6 0.038 14.2 13.6 2.1 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F HPS3_Mid PF14762.6 EAN33145.1 - 0.027 13.2 0.9 0.038 12.8 0.9 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region DUF261 PF03196.13 EAN33145.1 - 0.05 13.7 0.8 0.05 13.7 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF261 PP2C PF00481.21 EAN33146.1 - 4.9e-57 193.5 1.9 1.2e-48 166.0 0.7 2.5 3 0 0 3 3 3 2 Protein phosphatase 2C DUF1837 PF08878.11 EAN33146.1 - 0.16 11.8 2.0 0.29 10.9 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) FAINT PF04385.15 EAN33147.1 - 3.1e-05 23.9 0.2 5.5e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Collagen PF01391.18 EAN33147.1 - 0.023 14.5 13.5 0.048 13.4 13.5 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DNA_pol_phi PF04931.13 EAN33147.1 - 0.36 8.9 5.5 0.44 8.6 5.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Hydrolase_3 PF08282.12 EAN33149.1 - 4.6e-36 124.9 0.1 1.8e-35 122.9 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAN33149.1 - 9.6e-09 35.1 0.0 0.00012 21.7 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase FAINT PF04385.15 EAN33149.1 - 0.00023 21.2 1.7 0.0013 18.8 0.5 2.9 2 1 1 3 3 3 1 Domain of unknown function, DUF529 Sushi_2 PF09014.10 EAN33149.1 - 0.071 13.0 0.6 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Hydrolase PF00702.26 EAN33149.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAN33149.1 - 0.1 12.7 0.4 0.74 9.9 0.0 2.3 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase FAINT PF04385.15 EAN33150.1 - 0.026 14.6 0.1 9.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function, DUF529 Ribosomal_S14 PF00253.21 EAN33152.1 - 9.9e-14 50.8 0.0 1.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e TRAPPC10 PF12584.8 EAN33153.1 - 8.3e-06 25.6 0.0 2.7e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 NAD_binding_8 PF13450.6 EAN33154.1 - 4.3e-05 23.7 0.0 9.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EAN33154.1 - 0.082 12.1 0.0 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Csm1_N PF18504.1 EAN33156.1 - 0.00094 19.5 6.8 0.00094 19.5 6.8 2.2 2 1 1 3 3 3 1 Csm1 N-terminal domain DUF2046 PF09755.9 EAN33156.1 - 0.012 14.9 16.0 0.011 15.0 9.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) zf-ZPR1 PF03367.13 EAN33156.1 - 0.019 14.8 2.4 0.026 14.4 2.4 1.3 1 0 0 1 1 1 0 ZPR1 zinc-finger domain SHE3 PF17078.5 EAN33156.1 - 0.022 14.5 15.5 0.027 14.2 15.5 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Fez1 PF06818.15 EAN33156.1 - 0.033 14.6 7.2 0.048 14.1 7.2 1.4 1 1 0 1 1 1 0 Fez1 Atg14 PF10186.9 EAN33156.1 - 0.087 11.9 8.3 0.11 11.6 8.2 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1147 PF06615.11 EAN33156.1 - 0.097 12.7 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) TPR_MLP1_2 PF07926.12 EAN33156.1 - 0.18 11.8 10.2 0.088 12.9 5.6 2.4 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 EAN33156.1 - 0.32 11.5 13.4 0.73 10.3 8.9 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 LPP PF04728.13 EAN33156.1 - 0.36 11.3 0.1 0.36 11.3 0.1 2.5 2 1 1 3 3 2 0 Lipoprotein leucine-zipper DivIC PF04977.15 EAN33156.1 - 0.42 10.4 6.7 0.33 10.8 3.4 2.4 2 1 0 2 2 2 0 Septum formation initiator Rootletin PF15035.6 EAN33156.1 - 0.96 9.4 9.9 0.65 10.0 7.4 1.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Seryl_tRNA_N PF02403.22 EAN33156.1 - 1.1 9.6 14.0 3 8.1 8.9 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2570 PF10828.8 EAN33156.1 - 1.1 9.1 8.4 0.5 10.2 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF1664 PF07889.12 EAN33156.1 - 2.4 8.2 7.8 8.2 6.5 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 EAN33156.1 - 5.5 7.5 11.6 5 7.7 9.8 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region FAINT PF04385.15 EAN33157.1 - 0.055 13.5 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, DUF529 VPR PF00522.18 EAN33158.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 VPR/VPX protein Mod_r PF07200.13 EAN33160.1 - 2.8 8.1 6.6 12 5.9 5.1 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF5344 PF17279.2 EAN33160.1 - 8.6 7.0 11.4 3.4 8.3 2.1 3.9 3 1 1 4 4 4 0 Family of unknown function (DUF5344) FAINT PF04385.15 EAN33161.1 - 3.5e-95 312.2 158.6 3.8e-08 33.3 0.4 20.3 19 2 0 20 20 20 19 Domain of unknown function, DUF529 ANAPC4_WD40 PF12894.7 EAN33161.1 - 0.06 13.7 0.3 24 5.3 0.0 4.4 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain SCVP PF17619.2 EAN33161.1 - 7.2 7.5 7.4 1.4 9.8 0.1 3.7 5 0 0 5 5 5 0 Secreted clade V proteins MalF_P2 PF14785.6 EAN33162.1 - 0.21 11.6 2.0 0.24 11.4 0.2 1.9 2 1 0 2 2 2 0 Maltose transport system permease protein MalF P2 domain DUF4844 PF16133.5 EAN33162.1 - 1.2 9.7 7.8 0.98 10.0 2.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4844) FAINT PF04385.15 EAN33163.1 - 1.5e-12 47.4 9.5 6e-08 32.6 3.1 2.9 1 1 2 3 3 3 2 Domain of unknown function, DUF529 GH43_C2 PF17851.1 EAN33163.1 - 0.019 14.7 1.8 0.023 14.4 0.3 1.9 1 1 1 2 2 2 0 Beta xylosidase C-terminal Concanavalin A-like domain LAP1C PF05609.12 EAN33163.1 - 0.2 10.7 16.8 0.27 10.3 16.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SAPS PF04499.15 EAN33163.1 - 1.9 7.1 15.2 2.6 6.7 15.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 EAN33163.1 - 2.4 7.9 21.6 3.4 7.4 21.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4045 PF13254.6 EAN33163.1 - 3 7.4 21.1 3.9 7.0 21.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SOBP PF15279.6 EAN33163.1 - 4.6 7.8 11.8 6 7.4 11.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PA26 PF04636.13 EAN33163.1 - 4.7 6.0 12.6 6.7 5.5 12.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) UPF0242 PF06785.11 EAN33163.1 - 6.6 6.8 12.2 10 6.2 12.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Arf PF00025.21 EAN33164.1 - 5.4e-11 42.3 1.6 7.6e-11 41.8 1.6 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAN33164.1 - 1.5e-10 40.8 6.2 4e-10 39.4 6.2 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EAN33164.1 - 4.8e-07 29.5 1.3 1.5e-06 27.9 1.2 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EAN33164.1 - 2.9e-05 24.2 0.3 0.00015 22.0 0.3 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAN33164.1 - 7.3e-05 22.8 0.7 0.00035 20.6 0.7 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 EAN33164.1 - 0.00024 21.1 0.2 0.00046 20.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 EAN33164.1 - 0.012 15.2 1.1 0.049 13.2 0.1 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EAN33164.1 - 0.016 15.1 0.4 0.031 14.2 0.3 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 EAN33164.1 - 0.078 12.5 1.1 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EAN33164.1 - 0.097 12.4 1.7 2.9 7.7 0.0 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bud13 PF09736.9 EAN33166.1 - 3.9e-36 124.6 6.7 3.9e-36 124.6 6.7 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex zf_CCCH_4 PF18345.1 EAN33167.1 - 3.7e-07 30.0 1.3 8e-07 28.9 1.3 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EAN33167.1 - 8.1e-06 25.6 2.2 8.7e-06 25.5 0.6 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EAN33167.1 - 5.9e-05 23.7 0.0 0.00011 22.9 0.0 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 EAN33167.1 - 0.00024 20.8 0.9 0.0005 19.8 0.9 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EAN33167.1 - 0.0034 17.8 0.4 0.0098 16.3 0.4 1.9 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EAN33167.1 - 0.017 15.3 0.1 0.017 15.3 0.1 1.8 2 1 0 2 2 2 0 Zinc-finger containing family FYVE PF01363.21 EAN33167.1 - 3.2 7.9 8.0 0.86 9.8 4.3 2.2 2 1 0 2 2 2 0 FYVE zinc finger Peptidase_C1 PF00112.23 EAN33168.1 - 1.9e-30 106.6 4.1 3.6e-30 105.7 4.1 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EAN33168.1 - 0.024 13.4 3.2 0.052 12.3 1.0 2.2 2 0 0 2 2 2 0 Peptidase C1-like family Tho2 PF11262.8 EAN33169.1 - 1e-99 333.5 9.2 2.1e-99 332.5 9.2 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EAN33169.1 - 2.4e-05 24.3 0.2 2.4e-05 24.3 0.2 3.4 3 0 0 3 3 3 1 Transcription- and export-related complex subunit THOC2_N PF16134.5 EAN33170.1 - 1.1e-09 37.5 10.1 7.5e-09 34.8 10.1 2.2 1 1 0 1 1 1 1 THO complex subunit 2 N-terminus PP2C PF00481.21 EAN33171.1 - 4.6e-34 118.2 0.0 1.5e-30 106.7 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C THUMP PF02926.17 EAN33172.1 - 5.8e-07 29.7 3.9 0.00022 21.3 0.6 2.8 3 0 0 3 3 3 2 THUMP domain PDDEXK_9 PF08011.11 EAN33172.1 - 0.49 10.3 3.2 0.19 11.7 0.4 1.9 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily FAINT PF04385.15 EAN33173.1 - 1.2e-07 31.7 1.1 0.00024 21.1 0.0 2.9 2 1 1 3 3 3 2 Domain of unknown function, DUF529 DUF5476 PF17570.2 EAN33173.1 - 0.073 13.5 0.7 0.17 12.3 0.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5476) FAINT PF04385.15 EAN33174.1 - 0.054 13.5 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33175.1 - 7.5e-07 29.1 0.6 1.4e-06 28.2 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function, DUF529 VIR_N PF15912.5 EAN33175.1 - 7 6.2 11.9 12 5.4 11.9 1.4 1 1 0 1 1 1 0 Virilizer, N-terminal FAINT PF04385.15 EAN33176.1 - 0.00013 21.9 0.5 0.00027 20.9 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN33177.1 - 0.0013 18.8 9.1 0.0029 17.7 9.1 1.6 1 0 0 1 1 1 1 Tash protein PEST motif AAA PF00004.29 EAN33178.1 - 8.9e-43 145.9 0.0 2.1e-42 144.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAN33178.1 - 5.6e-14 51.7 0.1 1.1e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EAN33178.1 - 1.3e-06 28.7 0.0 2.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EAN33178.1 - 2.4e-06 27.6 0.0 1e-05 25.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAN33178.1 - 3.3e-06 27.6 0.1 4.4e-05 23.9 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EAN33178.1 - 1.8e-05 24.6 0.3 5.2e-05 23.1 0.3 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 EAN33178.1 - 7.8e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAN33178.1 - 0.00017 21.9 1.0 0.01 16.1 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_18 PF13238.6 EAN33178.1 - 0.00045 20.8 0.0 0.013 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAN33178.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EAN33178.1 - 0.0019 17.5 0.0 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EAN33178.1 - 0.0033 17.2 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EAN33178.1 - 0.0093 15.8 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EAN33178.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EAN33178.1 - 0.011 15.1 0.1 0.025 14.0 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EAN33178.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EAN33178.1 - 0.017 15.5 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EAN33178.1 - 0.021 14.2 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 EAN33178.1 - 0.027 13.9 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 EAN33178.1 - 0.028 14.1 0.0 0.088 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EAN33178.1 - 0.031 14.0 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EAN33178.1 - 0.032 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 EAN33178.1 - 0.043 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 EAN33178.1 - 0.053 12.6 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 EAN33178.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAN33178.1 - 0.065 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EAN33178.1 - 0.12 12.1 0.3 0.24 11.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 EAN33178.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 EAN33178.1 - 0.15 12.6 0.1 0.53 10.8 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_30 PF13604.6 EAN33178.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain FAINT PF04385.15 EAN33179.1 - 0.021 14.9 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33180.1 - 0.03 14.4 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Collagen PF01391.18 EAN33180.1 - 0.079 12.7 79.6 1.8e+04 -33.2 79.6 3.8 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Tfb5 PF06331.12 EAN33182.1 - 0.044 13.8 0.1 0.17 11.9 0.1 2.0 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 CHIP_TPR_N PF18391.1 EAN33183.1 - 0.04 14.7 5.2 5.7 7.8 0.1 3.9 3 0 0 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain Med9 PF07544.13 EAN33183.1 - 0.049 13.7 2.6 28 4.9 0.0 4.8 4 1 1 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 BCDHK_Adom3 PF10436.9 EAN33183.1 - 0.13 12.1 4.2 1.2 8.9 0.0 3.4 3 1 1 4 4 4 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Vps54 PF07928.12 EAN33183.1 - 2.3 8.7 7.7 19 5.7 1.3 5.0 3 2 1 4 4 4 0 Vps54-like protein Pro_isomerase PF00160.21 EAN33186.1 - 1.7e-46 158.4 0.9 3.2e-46 157.5 0.9 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 EAN33186.1 - 5.6e-31 106.7 0.0 1.3e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 EAN33186.1 - 1.6e-08 34.0 4.3 0.017 15.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAN33186.1 - 2.1e-08 33.6 3.3 0.034 14.3 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAN33186.1 - 2.9e-07 30.0 2.5 0.0042 16.7 0.1 3.5 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.6 EAN33186.1 - 1e-05 26.0 0.0 0.00025 21.6 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 EAN33186.1 - 0.00041 20.4 0.2 0.0046 17.0 0.1 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EAN33186.1 - 0.0058 16.8 2.5 3.2 8.2 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAN33186.1 - 0.016 15.5 0.1 0.29 11.5 0.1 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAN33186.1 - 0.017 15.1 0.2 8 6.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAN33186.1 - 0.018 15.1 0.1 0.03 14.5 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAN33186.1 - 0.029 15.2 0.1 2.6 9.1 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAN33186.1 - 0.036 14.6 0.9 2.3 8.8 0.1 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAN33186.1 - 0.096 13.4 0.4 0.93 10.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EAN33186.1 - 0.17 12.3 2.8 32 5.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PIG-S PF10510.9 EAN33187.1 - 2e-12 46.7 13.4 4.3e-12 45.7 13.4 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Actin PF00022.19 EAN33188.1 - 8.7e-144 479.1 0.0 5.3e-143 476.5 0.0 1.8 1 1 0 1 1 1 1 Actin FAD_binding_3 PF01494.19 EAN33191.1 - 7.1e-50 170.2 0.0 8.1e-32 110.8 0.0 2.9 2 1 1 3 3 3 3 FAD binding domain Pec_lyase PF09492.10 EAN33192.1 - 0.03 13.7 1.7 0.043 13.1 0.5 1.7 2 0 0 2 2 2 0 Pectic acid lyase RNase_P_p30 PF01876.16 EAN33194.1 - 2.9e-16 59.6 0.0 7.3e-16 58.3 0.0 1.6 1 1 0 1 1 1 1 RNase P subunit p30 WHEP-TRS PF00458.20 EAN33195.1 - 0.075 13.2 2.6 0.22 11.7 2.5 1.9 1 1 0 1 1 1 0 WHEP-TRS domain DnaJ PF00226.31 EAN33196.1 - 0.00047 20.2 0.0 0.0009 19.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain APP_Cu_bd PF12924.7 EAN33196.1 - 0.0038 17.9 2.2 0.6 10.9 2.2 2.8 1 1 0 1 1 1 1 Copper-binding of amyloid precursor, CuBD XPG_N PF00752.17 EAN33197.1 - 1e-27 96.6 0.0 1.2e-26 93.1 0.0 2.7 3 0 0 3 3 3 1 XPG N-terminal domain XPG_I PF00867.18 EAN33197.1 - 5.7e-27 93.9 0.2 5.7e-27 93.9 0.2 2.4 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 EAN33197.1 - 7.3e-05 23.3 2.6 0.0001 22.9 0.0 2.6 3 1 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 EAN33197.1 - 0.00016 21.6 0.0 0.00059 19.8 0.0 1.9 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_5 PF14520.6 EAN33197.1 - 0.025 15.2 0.0 0.15 12.7 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain PLDc_2 PF13091.6 EAN33197.1 - 0.072 13.0 0.4 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 PLD-like domain HHH PF00633.23 EAN33197.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_2 PF12826.7 EAN33197.1 - 0.13 12.3 0.0 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-RanBP PF00641.18 EAN33198.1 - 0.072 12.4 9.0 1.2 8.5 4.1 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others WHEP-TRS PF00458.20 EAN33199.1 - 0.075 13.2 2.6 0.22 11.7 2.5 1.9 1 1 0 1 1 1 0 WHEP-TRS domain DnaJ PF00226.31 EAN33200.1 - 0.00047 20.2 0.0 0.0009 19.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain APP_Cu_bd PF12924.7 EAN33200.1 - 0.0038 17.9 2.2 0.6 10.9 2.2 2.8 1 1 0 1 1 1 1 Copper-binding of amyloid precursor, CuBD GBP PF02263.19 EAN33201.1 - 8.7e-09 35.0 0.3 8.7e-09 35.0 0.3 2.9 3 0 0 3 3 3 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EAN33201.1 - 0.059 13.5 0.0 0.24 11.5 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase PF06745.13 EAN33201.1 - 0.11 11.9 0.4 0.33 10.3 0.4 1.8 1 0 0 1 1 1 0 KaiC Flavi_NS4B PF01349.17 EAN33201.1 - 0.18 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B SieB PF14163.6 EAN33201.1 - 0.35 10.4 5.9 0.087 12.3 0.2 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B DUF489 PF04356.12 EAN33201.1 - 1.3 9.0 5.1 2.6 8.0 2.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF489) Baculo_PEP_C PF04513.12 EAN33201.1 - 1.3 9.0 9.0 1 9.4 4.0 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA PF00004.29 EAN33202.1 - 6.4e-36 123.7 0.0 1.2e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EAN33202.1 - 7.6e-06 26.1 0.0 1.9e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EAN33202.1 - 2.4e-05 24.2 0.0 5.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EAN33202.1 - 0.00011 22.2 0.1 0.0013 18.7 0.0 2.8 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAN33202.1 - 0.00069 19.9 0.2 0.006 16.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 EAN33202.1 - 0.001 18.8 0.0 0.0025 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 EAN33202.1 - 0.0027 17.7 0.0 0.0081 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAN33202.1 - 0.0063 17.1 1.4 0.014 16.0 0.1 2.4 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 EAN33202.1 - 0.0072 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 EAN33202.1 - 0.011 15.3 0.2 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EAN33202.1 - 0.013 15.2 0.4 0.069 12.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAN33202.1 - 0.035 14.5 0.1 0.15 12.4 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 EAN33202.1 - 0.039 13.3 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EAN33202.1 - 0.066 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EAN33202.1 - 0.081 13.4 0.1 0.33 11.5 0.0 1.9 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EAN33202.1 - 0.081 13.2 0.0 0.35 11.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain MCM PF00493.23 EAN33202.1 - 0.085 11.9 0.1 0.16 11.0 0.1 1.5 1 0 0 1 1 1 0 MCM P-loop domain SKI PF01202.22 EAN33202.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_33 PF13671.6 EAN33202.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAN33202.1 - 0.14 12.4 0.2 0.42 10.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAN33202.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAN33202.1 - 0.2 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Form_Nir_trans PF01226.17 EAN33203.1 - 3.4e-55 186.9 20.3 4e-55 186.7 20.3 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter zf-RING_2 PF13639.6 EAN33204.1 - 5.3e-06 26.7 8.9 5.3e-06 26.7 8.9 2.4 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 EAN33204.1 - 3.6e-05 23.9 6.2 0.00015 21.8 6.2 2.2 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EAN33204.1 - 0.0028 17.9 7.9 0.0028 17.9 7.9 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAN33204.1 - 0.0081 16.2 2.6 0.0081 16.2 2.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EAN33204.1 - 0.03 14.2 10.2 0.13 12.1 10.2 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mrx7 PF10906.8 EAN33204.1 - 0.054 13.7 0.2 0.29 11.4 0.2 2.3 1 0 0 1 1 1 0 MIOREX complex component 7 DUF3361 PF11841.8 EAN33204.1 - 0.13 12.2 3.6 0.16 11.9 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Zn_ribbon_17 PF17120.5 EAN33204.1 - 0.15 11.7 9.3 0.24 11.0 6.0 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EAN33204.1 - 0.33 11.0 7.0 0.81 9.8 7.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.11 EAN33204.1 - 0.53 10.6 8.3 1.3 9.3 8.3 1.8 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.22 EAN33204.1 - 0.89 9.5 9.9 0.9 9.5 7.7 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Nse PF11789.8 EAN33204.1 - 2.6 7.9 5.1 8.7 6.3 5.1 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 EAN33204.1 - 3.4 7.6 15.0 0.22 11.4 9.4 2.1 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EAN33204.1 - 3.6 7.5 7.9 15 5.5 7.9 2.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Bax1-I PF01027.20 EAN33205.1 - 9.9e-31 107.2 29.4 1.1e-30 107.0 29.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 TruD PF01142.18 EAN33207.1 - 2.3e-56 191.4 0.8 9.7e-53 179.5 0.2 3.7 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) Synaptobrevin PF00957.21 EAN33208.1 - 5.4e-07 29.3 0.3 8e-07 28.8 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EAN33208.1 - 3.5e-05 23.8 0.1 6.2e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain GIT1_C PF12205.8 EAN33208.1 - 0.05 13.7 0.1 0.07 13.2 0.1 1.2 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term IMS PF00817.20 EAN33209.1 - 6.5e-20 71.7 0.0 1.3e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family DUF4223 PF13978.6 EAN33209.1 - 0.042 13.8 0.5 0.11 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Peptidase_S74 PF13884.6 EAN33209.1 - 0.075 13.4 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Chaperone of endosialidase PGM_PMM_I PF02878.16 EAN33210.1 - 3.6e-08 33.2 0.0 1.8e-06 27.7 0.0 2.6 2 1 1 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EAN33210.1 - 8e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Peptidase_M48_N PF16491.5 EAN33211.1 - 6e-19 68.6 9.0 6e-19 68.6 9.0 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EAN33211.1 - 1.2e-09 38.2 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF2715 PF10895.8 EAN33211.1 - 0.028 14.1 0.2 0.045 13.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2715) Phage_holin_3_6 PF07332.11 EAN33211.1 - 0.24 11.5 3.3 0.14 12.3 0.6 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Proteasome PF00227.26 EAN33212.1 - 4.3e-44 150.3 0.3 5.1e-44 150.0 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAN33212.1 - 1.3e-12 47.1 0.0 2.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RL11D PF11088.8 EAN33212.1 - 0.0056 16.9 0.2 0.23 11.8 0.1 2.4 2 0 0 2 2 2 1 Glycoprotein encoding membrane proteins RL5A and RL6 Peptidase_M48_N PF16491.5 EAN33213.1 - 1.3e-55 188.1 10.3 1.3e-55 188.1 10.3 2.2 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EAN33213.1 - 2.4e-36 125.4 0.0 4.4e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EAN33213.1 - 0.0079 15.4 1.3 0.063 12.5 0.2 2.1 2 0 0 2 2 2 1 BlaR1 peptidase M56 Arm_3 PF16186.5 EAN33213.1 - 0.017 14.7 0.4 0.032 13.8 0.4 1.4 1 0 0 1 1 1 0 Atypical Arm repeat MgtE PF01769.16 EAN33213.1 - 0.13 12.6 2.6 1 9.8 0.6 2.3 2 0 0 2 2 2 0 Divalent cation transporter Peptidase_M48_N PF16491.5 EAN33214.1 - 9.8e-24 84.2 9.4 2.7e-23 82.8 9.4 1.7 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EAN33214.1 - 3.7e-05 23.6 0.0 7.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Asp-Al_Ex PF06826.12 EAN33214.1 - 0.94 9.3 5.4 2.6 7.9 0.8 2.3 2 0 0 2 2 2 0 Predicted Permease Membrane Region Proteasome PF00227.26 EAN33215.1 - 4.3e-44 150.3 0.3 5.1e-44 150.0 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAN33215.1 - 1.3e-12 47.1 0.0 2.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RL11D PF11088.8 EAN33215.1 - 0.0056 16.9 0.2 0.23 11.8 0.1 2.4 2 0 0 2 2 2 1 Glycoprotein encoding membrane proteins RL5A and RL6 VWD PF00094.25 EAN33216.1 - 0.0086 16.4 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain Cgr1 PF03879.14 EAN33217.1 - 1.4e-07 31.9 20.8 1.9e-07 31.4 20.8 1.2 1 0 0 1 1 1 1 Cgr1 family DUF3347 PF11827.8 EAN33217.1 - 0.014 15.6 6.3 0.018 15.2 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DUF883 PF05957.13 EAN33217.1 - 0.19 12.4 3.9 0.34 11.5 3.8 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Folliculin PF11704.8 EAN33217.1 - 0.84 9.5 5.0 1.2 9.0 5.0 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport TMPIT PF07851.13 EAN33217.1 - 3.8 6.7 8.4 5 6.3 8.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein RRM_1 PF00076.22 EAN33218.1 - 3.1e-32 110.2 13.8 7.9e-16 57.7 0.7 5.3 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAN33218.1 - 0.00012 21.6 0.2 0.0072 15.9 0.1 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1681 PF07933.14 EAN33218.1 - 0.0015 18.2 0.2 0.0045 16.7 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Phage_TAC_13 PF16459.5 EAN33218.1 - 0.041 14.3 1.8 3.6 8.1 0.1 3.0 3 0 0 3 3 3 0 Phage tail assembly chaperone, TAC RRM_7 PF16367.5 EAN33218.1 - 0.083 13.0 0.6 35 4.6 0.1 3.8 3 2 0 3 3 3 0 RNA recognition motif Hepatitis_core PF00906.20 EAN33218.1 - 0.1 12.1 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Hepatitis core antigen LPP20 PF02169.16 EAN33218.1 - 4.2 7.8 8.1 0.56 10.6 0.2 3.1 2 0 0 2 2 2 0 LPP20 lipoprotein EF-hand_4 PF12763.7 EAN33219.1 - 2.3e-20 72.5 1.7 5.4e-09 35.9 0.0 3.0 3 1 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EAN33219.1 - 1.1e-05 24.6 0.1 0.017 14.6 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EAN33219.1 - 1.5e-05 24.8 2.1 0.0039 17.0 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EAN33219.1 - 0.0014 19.0 9.4 0.0015 18.9 0.9 3.2 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EAN33219.1 - 0.0029 17.4 0.7 0.83 9.8 0.1 3.5 3 0 0 3 3 3 1 EF-hand domain PI3K_P85_iSH2 PF16454.5 EAN33219.1 - 0.048 13.3 30.6 0.011 15.3 25.5 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Occludin_ELL PF07303.13 EAN33219.1 - 0.23 12.2 14.1 0.32 11.7 1.4 2.6 2 0 0 2 2 2 0 Occludin homology domain COG2 PF06148.11 EAN33219.1 - 0.51 10.4 23.0 0.95 9.5 4.0 3.4 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Topoisom_I_N PF02919.15 EAN33219.1 - 0.53 9.8 5.3 0.44 10.0 3.6 1.6 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Syntaxin-6_N PF09177.11 EAN33219.1 - 2.4 8.8 16.6 0.13 12.8 4.5 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DHR10 PF18595.1 EAN33219.1 - 5.4 7.1 28.7 0.24 11.5 3.2 3.1 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain ApoO PF09769.9 EAN33219.1 - 8.2 6.4 6.1 41 4.1 0.1 3.3 3 0 0 3 3 3 0 Apolipoprotein O Fez1 PF06818.15 EAN33219.1 - 8.9 6.7 26.4 4.9 7.5 10.9 2.2 1 1 1 2 2 2 0 Fez1 SIS PF01380.22 EAN33220.1 - 1.8e-30 105.5 2.7 2.2e-15 56.7 0.4 2.6 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EAN33220.1 - 1e-13 51.6 0.1 1.3e-08 35.1 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase domain GATase_7 PF13537.6 EAN33220.1 - 1.7e-05 24.7 0.0 0.048 13.6 0.0 2.5 2 0 0 2 2 2 2 Glutamine amidotransferase domain GATase_4 PF13230.6 EAN33220.1 - 0.025 13.5 0.0 0.05 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Cpn60_TCP1 PF00118.24 EAN33222.1 - 6.8e-159 529.6 0.1 7.8e-159 529.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3638 PF12340.8 EAN33223.1 - 7.3e-23 81.1 0.1 3.2e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EAN33223.1 - 5.6e-14 51.2 0.0 1.5e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_7 PF13499.6 EAN33223.1 - 0.00011 22.5 0.1 0.0013 19.1 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair Vps62 PF06101.11 EAN33223.1 - 0.00017 20.1 0.0 0.00032 19.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 EF-hand_6 PF13405.6 EAN33223.1 - 0.00032 20.4 0.3 0.0035 17.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EAN33223.1 - 0.012 15.1 0.2 0.012 15.1 0.2 2.6 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 EAN33223.1 - 0.16 11.5 1.1 0.35 10.5 0.1 2.2 2 0 0 2 2 2 0 EF hand DUF3994 PF13159.6 EAN33223.1 - 5.8 7.5 6.0 6.3 7.4 1.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) FAINT PF04385.15 EAN33224.1 - 7.7e-12 45.1 23.7 9.9e-05 22.3 1.7 3.8 3 1 0 3 3 3 3 Domain of unknown function, DUF529 Cadherin_5 PF17892.1 EAN33224.1 - 0.045 13.7 1.7 3.3 7.8 0.1 2.8 2 0 0 2 2 2 0 Cadherin-like domain ABC_tran PF00005.27 EAN33225.1 - 9.8e-35 120.1 0.0 6.7e-19 68.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAN33225.1 - 6.7e-11 42.3 14.1 6.7e-11 42.3 14.1 3.5 4 1 0 4 4 2 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 EAN33225.1 - 8.4e-07 29.0 0.3 0.0086 16.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EAN33225.1 - 1e-05 25.2 0.6 0.037 13.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EAN33225.1 - 2e-05 23.9 0.2 0.037 13.3 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin MeaB PF03308.16 EAN33225.1 - 0.00033 19.7 0.2 0.006 15.6 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 EAN33225.1 - 0.00049 20.0 3.1 0.85 9.4 0.1 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EAN33225.1 - 0.00062 19.5 0.2 0.048 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAN33225.1 - 0.0009 19.5 0.7 0.65 10.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EAN33225.1 - 0.00093 19.6 0.1 0.63 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 EAN33225.1 - 0.0012 18.0 0.1 0.15 11.1 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EAN33225.1 - 0.0021 18.1 0.3 0.24 11.5 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EAN33225.1 - 0.0051 17.3 5.6 0.64 10.5 1.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.7 EAN33225.1 - 0.012 14.6 1.2 2.1 7.2 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain KAP_NTPase PF07693.14 EAN33225.1 - 0.013 14.7 0.1 2.3 7.3 0.0 3.0 3 0 0 3 3 3 0 KAP family P-loop domain ATP_bind_1 PF03029.17 EAN33225.1 - 0.014 15.1 1.5 2.7 7.7 0.1 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 EAN33225.1 - 0.02 13.8 0.9 1.3 7.9 0.3 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATPase_2 PF01637.18 EAN33225.1 - 0.024 14.5 0.2 7.2 6.4 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EAN33225.1 - 0.028 14.8 0.4 24 5.4 0.0 3.8 4 0 0 4 4 3 0 RNA helicase NB-ARC PF00931.22 EAN33225.1 - 0.032 13.4 1.1 0.24 10.5 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 EAN33225.1 - 0.044 13.4 1.5 2.2 7.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EAN33225.1 - 0.046 14.3 0.1 5.6 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EAN33225.1 - 0.051 13.6 2.1 0.69 10.0 0.2 3.1 3 0 0 3 3 3 0 Dynamin family SMC_N PF02463.19 EAN33225.1 - 0.07 12.6 3.5 0.11 11.9 0.3 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EAN33225.1 - 0.077 12.9 2.4 5 7.0 0.1 3.0 3 0 0 3 3 3 0 NACHT domain NTPase_1 PF03266.15 EAN33225.1 - 0.089 12.7 2.8 5.5 6.9 0.1 2.8 3 0 0 3 3 2 0 NTPase FtsK_SpoIIIE PF01580.18 EAN33225.1 - 0.099 12.0 0.2 7.1 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family RA PF00788.23 EAN33225.1 - 0.13 12.9 0.2 28 5.5 0.1 2.5 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain DUF815 PF05673.13 EAN33225.1 - 0.13 11.4 0.4 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EAN33225.1 - 0.21 11.1 0.0 14 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EAN33225.1 - 0.21 11.5 2.6 1.3 8.9 0.4 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 EAN33225.1 - 0.27 11.6 0.7 21 5.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EAN33225.1 - 0.31 11.1 5.5 0.51 10.4 0.4 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain UL45 PF05473.12 EAN33225.1 - 0.5 10.0 5.8 6.3 6.4 0.1 3.4 3 0 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like Aldo_ket_red PF00248.21 EAN33226.1 - 8.4e-53 179.5 0.0 1.3e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Arm-DNA-bind_1 PF09003.10 EAN33226.1 - 0.021 14.9 0.1 0.081 13.1 0.1 2.0 1 0 0 1 1 1 0 Bacteriophage lambda integrase, Arm DNA-binding domain SRTM1 PF15872.5 EAN33227.1 - 0.074 13.2 4.1 0.16 12.2 4.1 1.6 1 1 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 NIF PF03031.18 EAN33228.1 - 1.9e-22 79.7 1.3 4.1e-22 78.6 1.3 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Metallophos PF00149.28 EAN33229.1 - 2.4e-28 100.0 0.2 4.3e-28 99.2 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EAN33229.1 - 8.7e-13 48.4 0.1 2.1e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 EAN33229.1 - 3e-12 45.8 1.0 0.00013 21.6 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAN33229.1 - 9.3e-11 41.0 0.6 0.00037 20.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAN33229.1 - 4.5e-05 23.0 0.0 0.052 13.2 0.1 2.8 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 EAN33229.1 - 0.0029 17.7 0.8 1.4 9.3 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Phosducin PF02114.16 EAN33230.1 - 1.4e-06 27.5 0.1 1.7e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EAN33230.1 - 2.3e-06 27.5 0.0 3.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin WASH_WAHD PF11945.8 EAN33231.1 - 0.11 12.0 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 WAHD domain of WASH complex Ribosomal_S8e PF01201.22 EAN33233.1 - 1.1e-54 184.3 0.0 1.3e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e FAINT PF04385.15 EAN33234.1 - 5.2e-13 48.9 24.5 1.5e-05 24.9 4.6 4.8 4 2 1 5 5 5 3 Domain of unknown function, DUF529 ABC_tran PF00005.27 EAN33235.2 - 2.3e-31 109.2 0.0 8.7e-17 61.9 0.0 2.7 2 1 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EAN33235.2 - 1.9e-06 27.9 0.6 0.058 13.3 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 EAN33235.2 - 4.1e-06 26.0 0.1 0.0016 17.5 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EAN33235.2 - 1.2e-05 24.6 0.3 0.041 13.2 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 EAN33235.2 - 0.00032 21.1 0.0 0.3 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EAN33235.2 - 0.00088 19.0 1.0 1.6 8.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EAN33235.2 - 0.0054 16.6 2.0 0.6 9.9 0.1 3.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EAN33235.2 - 0.0065 16.5 0.4 0.29 11.2 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EAN33235.2 - 0.0067 16.7 0.7 1.1 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EAN33235.2 - 0.0075 16.2 0.2 1.3 8.9 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_10 PF12846.7 EAN33235.2 - 0.0076 15.2 0.1 2.5 6.9 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_30 PF13604.6 EAN33235.2 - 0.0099 15.6 0.4 0.17 11.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EAN33235.2 - 0.014 15.9 0.0 3.9 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EAN33235.2 - 0.031 13.2 2.0 1.8 7.4 0.7 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.14 EAN33235.2 - 0.032 14.1 1.1 1.1 9.1 0.4 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.6 EAN33235.2 - 0.033 14.7 5.7 0.66 10.4 0.9 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EAN33235.2 - 0.036 14.5 0.1 7.5 7.0 0.0 3.1 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 EAN33235.2 - 0.039 13.9 1.2 3.2 7.6 0.1 2.7 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 EAN33235.2 - 0.061 12.5 1.0 0.6 9.2 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 EAN33235.2 - 0.095 12.3 0.0 5.6 6.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EAN33235.2 - 0.097 11.7 0.3 1.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF815 PF05673.13 EAN33235.2 - 0.13 11.4 0.3 0.88 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 EAN33235.2 - 0.17 11.4 2.7 2.6 7.6 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EAN33235.2 - 0.27 11.1 3.0 10 6.0 0.2 2.4 2 0 0 2 2 2 0 NTPase SMC_N PF02463.19 EAN33235.2 - 0.37 10.2 4.2 0.56 9.6 0.4 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EAN33235.2 - 2.8 8.0 8.3 0.27 11.3 0.3 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain Apocytochr_F_C PF01333.19 EAN33236.1 - 0.0097 15.9 0.8 0.085 12.9 0.7 2.3 2 0 0 2 2 2 1 Apocytochrome F, C-terminal FAINT PF04385.15 EAN33237.1 - 0.00056 19.9 8.2 0.00056 19.9 8.2 2.4 2 1 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33238.1 - 3.1e-06 27.1 2.6 0.0001 22.3 0.3 2.7 2 1 1 3 3 3 2 Domain of unknown function, DUF529 CD4-extracel PF09191.10 EAN33238.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 CD4, extracellular Josephin PF02099.17 EAN33238.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Josephin Tash_PEST PF07708.11 EAN33239.1 - 1.7e-05 24.8 3.5 7.3e-05 22.8 3.5 2.1 1 0 0 1 1 1 1 Tash protein PEST motif FAINT PF04385.15 EAN33239.1 - 3.2 7.9 12.0 0.11 12.6 2.6 2.7 2 0 0 2 2 2 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33240.1 - 1.1e-10 41.4 3.9 1.5e-05 24.9 0.6 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 S100PBPR PF15427.6 EAN33240.1 - 0.085 12.1 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 S100P-binding protein Tash_PEST PF07708.11 EAN33242.1 - 9.8e-07 28.7 1.2 9.8e-07 28.7 1.2 2.3 2 0 0 2 2 2 1 Tash protein PEST motif FAINT PF04385.15 EAN33242.1 - 0.089 12.9 3.6 1.1 9.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33243.1 - 7.5e-07 29.1 10.9 2.3e-05 24.3 2.0 2.8 2 0 0 2 2 2 2 Domain of unknown function, DUF529 DUF4734 PF15881.5 EAN33243.1 - 0.089 13.0 1.3 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) Taeniidae_ag PF05596.11 EAN33243.1 - 0.15 12.1 0.0 3.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Taeniidae antigen FAINT PF04385.15 EAN33244.1 - 0.00064 19.7 10.5 0.00079 19.4 1.2 3.8 3 1 1 4 4 4 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33245.1 - 5.4e-22 77.6 39.9 7.4e-07 29.1 3.6 4.6 4 1 0 4 4 4 4 Domain of unknown function, DUF529 Pan3_PK PF18101.1 EAN33245.1 - 0.012 15.6 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 Pan3 Pseudokinase domain FAINT PF04385.15 EAN33246.1 - 4.8e-21 74.6 19.7 1.5e-08 34.5 4.4 3.7 3 0 0 3 3 3 3 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33247.1 - 8.9e-157 509.5 228.8 1.1e-09 38.2 1.9 32.0 31 0 0 31 31 31 31 Domain of unknown function, DUF529 GrlR PF16518.5 EAN33247.1 - 5.9e-06 26.2 7.3 2.5 8.1 0.0 8.0 9 0 0 9 9 9 3 T3SS negative regulator,GrlR BBS2_Mid PF14783.6 EAN33247.1 - 0.13 12.4 14.0 2.7 8.1 0.3 6.1 7 0 0 7 7 7 0 Ciliary BBSome complex subunit 2, middle region DUF1640 PF07798.11 EAN33248.1 - 0.0012 18.9 1.5 0.16 12.0 0.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) ADIP PF11559.8 EAN33248.1 - 0.02 15.0 1.9 0.035 14.2 1.9 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HAP1_N PF04849.13 EAN33248.1 - 0.022 14.0 1.9 0.047 12.9 1.9 1.5 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Allexi_40kDa PF05549.11 EAN33248.1 - 0.028 13.9 0.9 0.047 13.2 0.9 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein OmpH PF03938.14 EAN33248.1 - 0.031 14.6 2.0 0.031 14.6 2.0 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CLZ PF16526.5 EAN33248.1 - 0.036 14.4 0.6 0.073 13.4 0.6 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BST2 PF16716.5 EAN33248.1 - 0.049 14.2 3.0 0.11 13.1 3.0 1.6 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 ABC_tran_CTD PF16326.5 EAN33248.1 - 0.085 13.1 2.9 0.23 11.7 2.9 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF4407 PF14362.6 EAN33248.1 - 0.1 12.0 2.8 0.13 11.6 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 EAN33248.1 - 0.13 10.9 1.3 0.19 10.3 1.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A FAINT PF04385.15 EAN33248.1 - 0.14 12.2 0.4 0.34 11.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Lge1 PF11488.8 EAN33248.1 - 0.19 11.9 3.7 0.89 9.8 3.4 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Spc24 PF08286.11 EAN33248.1 - 0.3 11.4 1.9 0.36 11.1 0.7 1.7 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 AATF-Che1 PF13339.6 EAN33248.1 - 1.4 9.6 5.8 0.4 11.3 1.3 2.0 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor bZIP_2 PF07716.15 EAN33248.1 - 5.9 7.0 6.5 12 6.0 6.5 1.5 1 0 0 1 1 1 0 Basic region leucine zipper FAINT PF04385.15 EAN33249.1 - 1.8e-05 24.7 1.6 1.8e-05 24.7 1.6 2.7 2 1 0 2 2 2 1 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN33250.1 - 9.3e-09 35.2 2.0 2.7e-08 33.7 2.0 1.9 1 0 0 1 1 1 1 Tash protein PEST motif FAINT PF04385.15 EAN33250.1 - 0.27 11.3 8.2 13 6.0 3.6 3.3 2 1 0 2 2 2 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33251.1 - 3.5e-05 23.8 5.3 0.087 12.9 1.1 2.7 2 0 0 2 2 2 2 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33253.1 - 0.00011 22.2 10.2 0.033 14.3 0.9 3.2 2 1 0 2 2 2 2 Domain of unknown function, DUF529 ABC_tran PF00005.27 EAN33255.1 - 4.1e-31 108.3 0.0 1e-17 64.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EAN33255.1 - 3e-06 27.2 1.0 0.035 14.0 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EAN33255.1 - 4.2e-06 26.2 0.1 0.044 13.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 EAN33255.1 - 0.00043 20.0 1.1 0.69 9.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MeaB PF03308.16 EAN33255.1 - 0.00068 18.7 0.0 0.089 11.8 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EAN33255.1 - 0.016 15.5 0.3 1.3 9.2 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 EAN33255.1 - 0.021 15.2 0.0 4.1 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EAN33255.1 - 0.028 14.1 0.0 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAN33255.1 - 0.032 14.7 3.5 0.51 10.8 0.6 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EAN33255.1 - 0.034 13.1 0.4 2.2 7.1 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_21 PF13304.6 EAN33255.1 - 0.035 13.9 1.2 0.96 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EAN33255.1 - 0.036 14.2 0.1 0.45 10.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.13 EAN33255.1 - 0.057 12.6 0.3 0.16 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 EAN33255.1 - 0.064 13.2 0.1 6.5 6.6 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EAN33255.1 - 0.07 12.7 0.0 12 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 EAN33255.1 - 0.076 13.0 0.2 16 5.5 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE VraX PF17412.2 EAN33255.1 - 0.076 12.7 0.9 0.54 9.9 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function NB-ARC PF00931.22 EAN33255.1 - 0.077 12.2 0.5 0.57 9.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 EAN33255.1 - 0.088 12.7 0.2 6.3 6.7 0.0 2.9 3 0 0 3 3 3 0 NACHT domain MobB PF03205.14 EAN33255.1 - 0.25 11.2 1.2 2.1 8.2 0.2 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 EAN33255.1 - 0.89 9.6 3.1 0.69 10.0 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 EAN33255.1 - 1.7 8.5 3.3 25 4.7 0.0 2.6 3 0 0 3 3 3 0 NTPase HIT PF01230.23 EAN33256.1 - 1.8e-21 76.7 0.0 4.3e-21 75.5 0.0 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EAN33256.1 - 3e-19 69.6 0.1 4.4e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding RNase_PH PF01138.21 EAN33257.1 - 1.2e-18 67.9 0.0 1.6e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF2152 PF10222.9 EAN33257.1 - 0.08 11.3 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) DUF2116 PF09889.9 EAN33258.1 - 0.057 13.4 0.5 3.5 7.7 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RIBIOP_C PF04950.12 EAN33259.1 - 7.4e-94 314.4 0.0 1.1e-93 313.8 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EAN33259.1 - 5e-13 49.0 0.0 1.2e-11 44.5 0.0 2.7 2 0 0 2 2 2 1 AARP2CN (NUC121) domain Sortilin-Vps10 PF15902.5 EAN33260.1 - 1.3e-101 340.7 2.7 1.1e-52 179.4 0.1 2.7 2 1 1 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EAN33260.1 - 3.1e-38 131.8 0.8 4.7e-38 131.2 0.8 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR_3 PF13859.6 EAN33260.1 - 0.011 15.1 0.8 0.45 9.7 0.2 2.9 3 0 0 3 3 3 0 BNR repeat-like domain UCR_UQCRX_QCR9 PF05365.12 EAN33260.1 - 0.07 13.1 1.3 0.17 11.9 0.0 2.4 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like BNR PF02012.20 EAN33260.1 - 0.15 12.2 19.4 1.6 9.0 0.0 7.4 8 0 0 8 8 8 0 BNR/Asp-box repeat preSET_CXC PF18264.1 EAN33260.1 - 0.83 10.2 5.7 9.4 6.8 2.9 2.5 2 0 0 2 2 2 0 CXC domain PA14 PF07691.12 EAN33261.1 - 3.7e-23 81.9 0.0 6.9e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain fn2 PF00040.19 EAN33261.1 - 0.0052 17.0 1.3 0.0052 17.0 1.3 1.9 2 0 0 2 2 2 1 Fibronectin type II domain GLEYA PF10528.9 EAN33261.1 - 0.016 15.6 0.0 0.058 13.8 0.0 2.0 2 0 0 2 2 2 0 GLEYA domain Tup_N PF08581.10 EAN33261.1 - 0.13 12.6 0.6 1.1 9.6 0.3 2.3 2 0 0 2 2 2 0 Tup N-terminal cwf18 PF08315.12 EAN33262.1 - 1.2e-17 64.9 0.4 1.6e-17 64.4 0.4 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor RelB_N PF18506.1 EAN33262.1 - 0.13 12.0 0.8 0.45 10.4 0.1 2.2 2 1 0 2 2 2 0 RelB Antitoxin alpha helical domain CNOT1_TTP_bind PF16417.5 EAN33264.1 - 0.26 10.4 4.9 0.081 12.1 0.6 2.1 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 TTP binding domain WSD PF15613.6 EAN33265.1 - 0.046 14.2 15.2 0.056 13.9 0.0 4.9 5 1 0 5 5 5 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DNMT1-RFD PF12047.8 EAN33266.1 - 0.0015 18.6 0.0 0.005 16.9 0.0 2.0 1 1 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain SspB PF04386.13 EAN33267.1 - 0.02 14.8 0.3 0.024 14.5 0.3 1.4 1 1 0 1 1 1 0 Stringent starvation protein B Aminotran_5 PF00266.19 EAN33268.1 - 1.1e-85 287.9 0.0 1.4e-85 287.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EAN33268.1 - 4.4e-07 29.5 0.0 1.3e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EAN33268.1 - 0.00092 18.0 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EAN33268.1 - 0.0031 16.9 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EAN33268.1 - 0.085 11.4 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CS PF04969.16 EAN33269.1 - 8.5e-10 39.5 0.1 2.3e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 CS domain DNA_pol_B_exo2 PF10108.9 EAN33269.1 - 0.052 13.2 0.1 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB CD99L2 PF12301.8 EAN33269.1 - 4.1 7.7 7.4 0.13 12.6 0.7 1.8 2 0 0 2 2 2 0 CD99 antigen like protein 2 Peptidase_A25 PF03418.14 EAN33271.1 - 0.018 14.0 0.0 0.02 13.8 0.0 1.0 1 0 0 1 1 1 0 Germination protease Cytokin_check_N PF10407.9 EAN33271.1 - 0.14 12.1 0.9 0.83 9.6 0.5 2.1 1 1 1 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Dus PF01207.17 EAN33272.1 - 7.7e-46 156.6 0.0 1.8e-44 152.1 0.0 2.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) RNA_pol_A_bac PF01000.26 EAN33273.1 - 4.7e-23 81.7 0.0 1.2e-22 80.4 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EAN33273.1 - 3.8e-18 64.7 0.0 5.2e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_21 PF14697.6 EAN33273.1 - 0.011 15.9 0.6 0.011 15.9 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain 2OG-FeII_Oxy_2 PF13532.6 EAN33274.1 - 5.4e-16 59.4 0.0 7.6e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GatB_N PF02934.15 EAN33275.1 - 9.8e-52 176.0 0.0 6.7e-47 160.2 0.0 2.2 1 1 0 2 2 2 2 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EAN33275.1 - 0.0041 17.0 0.0 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 GatB domain Cas_Csd1 PF09709.10 EAN33278.1 - 0.0061 15.3 0.0 0.013 14.2 0.0 1.6 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csd1) Rep_Org_C PF06926.11 EAN33278.1 - 0.019 15.2 1.2 0.081 13.2 1.2 2.0 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus DUF1505 PF07403.11 EAN33278.1 - 0.077 13.2 1.2 0.14 12.3 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1505) DnaJ_C PF01556.18 EAN33279.1 - 1.3e-35 122.6 0.1 1.7e-35 122.3 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAN33279.1 - 1.9e-23 82.3 0.3 3.1e-23 81.7 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EAN33279.1 - 0.0089 16.4 4.8 0.019 15.3 4.8 1.5 1 0 0 1 1 1 1 DnaJ central domain TB PF00683.17 EAN33279.1 - 0.11 12.3 0.6 0.27 11.0 0.6 1.7 1 0 0 1 1 1 0 TB domain ORC2 PF04084.14 EAN33280.1 - 2.8e-25 88.9 1.7 9.7e-18 64.2 0.1 2.0 1 1 1 2 2 2 2 Origin recognition complex subunit 2 TBCC PF07986.12 EAN33280.1 - 0.11 12.2 0.2 0.21 11.3 0.2 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor C PAP_central PF04928.17 EAN33281.1 - 6.2e-99 330.0 0.0 8e-99 329.6 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EAN33281.1 - 1.1e-17 64.1 2.0 3.9e-08 33.1 0.1 2.4 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EAN33281.1 - 1.2e-07 31.9 0.0 3.8e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 EAN33281.1 - 0.026 14.8 1.0 0.47 10.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4269) Polbeta PF18765.1 EAN33281.1 - 0.075 13.1 1.2 0.18 11.9 0.0 2.3 3 0 0 3 3 3 0 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 EAN33281.1 - 0.54 10.0 3.1 0.63 9.8 0.1 2.6 3 1 0 3 3 3 0 Nrap protein PAP/OAS-like domain Carm_PH PF17888.1 EAN33282.1 - 0.19 12.1 0.0 0.6 10.5 0.0 1.8 2 0 0 2 2 2 0 Carmil pleckstrin homology domain Brix PF04427.18 EAN33283.1 - 1.8e-33 116.3 0.5 2.6e-33 115.7 0.5 1.2 1 0 0 1 1 1 1 Brix domain Exo5 PF09810.9 EAN33284.1 - 7.8e-49 167.1 19.8 6.5e-28 98.3 4.8 3.1 1 1 2 3 3 3 3 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EAN33284.1 - 4.1e-07 30.2 0.9 4.1e-07 30.2 0.9 1.5 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily TetR_C_2 PF08361.11 EAN33284.1 - 0.01 16.0 0.1 0.17 12.0 0.0 2.9 3 0 0 3 3 3 0 MAATS-type transcriptional repressor, C-terminal region RNase_HII PF01351.18 EAN33285.1 - 1.2e-50 172.1 0.0 1.5e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII AKAP7_NLS PF10469.9 EAN33286.1 - 1.6e-07 31.4 8.0 1.1e-06 28.7 7.9 2.2 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 EAN33286.1 - 0.1 12.8 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 LigT like Phosphoesterase Hexokinase_1 PF00349.21 EAN33287.1 - 3.9e-54 183.6 0.0 5.1e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EAN33287.1 - 4.5e-46 157.2 0.0 6.5e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EAN33289.1 - 2.1e-54 184.4 0.0 2.8e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EAN33289.1 - 9.9e-46 156.1 0.0 1.4e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Surp PF01805.20 EAN33290.1 - 3.1e-06 27.1 0.8 5.5e-06 26.3 0.2 1.7 1 1 1 2 2 2 1 Surp module CPW_WPC PF09717.10 EAN33291.1 - 6.6e-05 23.8 0.3 0.00012 23.0 0.1 1.5 1 1 1 2 2 2 1 Plasmodium falciparum domain of unknown function (CPW_WPC) DUF3567 PF12091.8 EAN33292.1 - 0.11 12.6 0.1 2.6 8.2 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3567) Kelch_4 PF13418.6 EAN33293.1 - 4.2e-09 36.3 3.6 0.0003 20.7 0.3 2.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EAN33293.1 - 4e-06 26.3 2.3 0.00019 21.0 0.1 2.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 EAN33293.1 - 4.5e-06 26.8 0.9 0.026 14.8 0.2 2.3 1 1 1 2 2 2 2 Kelch motif Kelch_5 PF13854.6 EAN33293.1 - 1.9e-05 24.5 0.3 0.064 13.3 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 EAN33293.1 - 0.00029 21.0 4.5 0.0032 17.7 0.1 2.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 EAN33293.1 - 0.00032 20.6 2.0 0.029 14.4 0.1 2.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 EAN33294.1 - 4.4e-09 36.2 3.3 0.0022 18.0 0.0 3.3 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EAN33294.1 - 1.7e-08 34.3 8.3 0.00026 20.9 0.1 3.3 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 EAN33294.1 - 4.6e-07 29.6 2.3 0.51 10.4 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 EAN33294.1 - 1.4e-05 24.5 3.5 0.00057 19.4 0.6 2.6 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 EAN33294.1 - 8.8e-05 22.7 4.7 0.14 12.5 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 EAN33294.1 - 0.00043 20.5 3.1 0.032 14.5 0.1 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain EGF_2 PF07974.13 EAN33294.1 - 3.7 8.0 17.7 0.43 11.0 13.1 1.9 2 0 0 2 2 2 0 EGF-like domain Sin_N PF04801.13 EAN33295.1 - 5.1e-32 111.6 0.5 2.4e-23 83.0 0.0 3.2 3 0 0 3 3 3 3 Sin-like protein conserved region DUF1160 PF06648.11 EAN33295.1 - 0.025 14.6 1.1 0.079 13.0 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1160) Sod_Ni PF09055.11 EAN33295.1 - 0.087 13.4 0.3 0.19 12.3 0.3 1.5 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase CENP-F_leu_zip PF10473.9 EAN33296.1 - 0.053 13.5 12.2 0.15 12.1 12.2 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 EAN33296.1 - 0.22 11.7 12.4 0.77 9.9 12.4 2.0 1 0 0 1 1 1 0 Tropomyosin like TMF_TATA_bd PF12325.8 EAN33296.1 - 1.7 8.9 13.2 0.1 12.8 5.2 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4094 PF13334.6 EAN33296.1 - 2 8.9 5.6 0.68 10.4 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) CENP-H PF05837.12 EAN33296.1 - 3.2 8.2 12.2 0.42 11.0 6.0 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) OPA3 PF07047.12 EAN33297.1 - 4.3e-33 113.8 0.0 5.4e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) TANGO2 PF05742.12 EAN33298.1 - 0.0028 17.7 0.3 0.0028 17.7 0.3 1.5 2 0 0 2 2 2 1 Transport and Golgi organisation 2 DEAD PF00270.29 EAN33299.1 - 9.9e-31 106.8 0.1 2.3e-30 105.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN33299.1 - 7e-24 84.3 0.0 1.7e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN33299.1 - 0.0014 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAN33299.1 - 0.025 14.9 0.1 0.14 12.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain TPR_2 PF07719.17 EAN33303.1 - 1.6e-08 34.0 0.1 2.8 8.3 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAN33303.1 - 5.2e-06 26.9 0.0 0.31 11.6 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAN33303.1 - 0.00062 20.2 0.6 0.19 12.4 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAN33303.1 - 0.0024 18.5 0.0 31 5.7 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAN33303.1 - 0.0033 17.5 2.4 9.2 6.8 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat Adaptin_binding PF10199.9 EAN33303.1 - 0.01 16.4 1.8 0.023 15.3 0.4 2.1 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 TPR_1 PF00515.28 EAN33303.1 - 0.025 14.4 0.1 5 7.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAN33304.1 - 0.0079 16.3 0.8 0.043 14.0 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 EAN33304.1 - 0.094 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Tetratrico peptide repeat RAP PF08373.10 EAN33305.1 - 0.00017 21.6 1.1 0.0016 18.5 0.1 2.5 2 0 0 2 2 2 1 RAP domain NifU PF01106.17 EAN33306.1 - 8.9e-19 67.4 0.0 1.3e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 NifU-like domain HEPN_Apea PF18739.1 EAN33307.1 - 3.8 8.0 7.1 0.29 11.6 0.5 2.3 2 1 0 2 2 2 0 Apea-like HEPN PP2C PF00481.21 EAN33308.1 - 5.1e-38 131.2 0.0 6.8e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EAN33308.1 - 0.044 13.4 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C YbfN PF13982.6 EAN33308.1 - 0.047 14.0 0.0 4.3 7.7 0.0 2.7 3 0 0 3 3 3 0 YbfN-like lipoprotein ABC1 PF03109.16 EAN33309.1 - 1.8e-31 108.7 0.0 4e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EAN33309.1 - 0.015 15.2 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L33 PF00471.20 EAN33310.1 - 3.7e-19 68.9 2.2 4.7e-19 68.6 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 ACBP PF00887.19 EAN33311.1 - 5.6e-30 103.4 1.0 6.1e-30 103.3 1.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein AP2 PF00847.20 EAN33312.1 - 2.3e-14 53.4 2.9 2.3e-14 53.4 2.9 2.3 2 0 0 2 2 2 1 AP2 domain Gal4_dimer PF03902.13 EAN33312.1 - 0.19 11.9 1.4 0.71 10.1 0.3 2.6 2 0 0 2 2 2 0 Gal4-like dimerisation domain JmjN PF02375.17 EAN33313.1 - 2.7e-09 36.8 0.1 5.3e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 jmjN domain JmjC PF02373.22 EAN33314.1 - 8.7e-13 48.7 0.0 1.9e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 EAN33314.1 - 2.7e-09 37.2 9.2 1e-08 35.4 9.2 2.1 1 0 0 1 1 1 1 C5HC2 zinc finger IRF-2BP1_2 PF11261.8 EAN33314.1 - 0.023 14.3 3.5 0.27 10.8 4.0 2.3 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger HEAT PF02985.22 EAN33316.1 - 3e-12 45.7 0.0 0.0012 18.9 0.0 5.2 3 0 0 3 3 3 3 HEAT repeat HEAT_EZ PF13513.6 EAN33316.1 - 4.1e-09 36.8 0.6 6.3e-06 26.6 0.0 5.2 6 0 0 6 6 6 1 HEAT-like repeat IBN_N PF03810.19 EAN33316.1 - 0.00012 21.9 0.3 0.0016 18.3 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF577 PF04510.12 EAN33316.1 - 0.00093 19.1 1.5 0.11 12.4 0.0 3.1 3 0 0 3 3 3 1 Family of unknown function (DUF577) HEAT_2 PF13646.6 EAN33316.1 - 0.0019 18.5 0.0 0.18 12.2 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats TIP120 PF08623.10 EAN33316.1 - 0.035 13.9 0.1 1 9.1 0.0 3.2 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.7 EAN33316.1 - 0.075 13.1 5.4 0.78 9.8 0.1 3.1 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EAN33316.1 - 0.11 12.6 1.8 2.3 8.4 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Pribosyltran PF00156.27 EAN33317.1 - 3.5e-08 33.1 0.0 4.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 EAN33317.1 - 0.068 12.7 0.0 0.089 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase UPRTase PF14681.6 EAN33317.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF2958 PF11171.8 EAN33319.1 - 0.046 14.0 0.0 0.058 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) Methyltr_RsmB-F PF01189.17 EAN33320.1 - 3.5e-36 124.8 0.0 8.5e-35 120.2 0.0 2.7 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F RST PF12174.8 EAN33320.1 - 0.1 12.5 0.1 0.35 10.8 0.1 1.9 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain HECT PF00632.25 EAN33322.1 - 3.8e-68 230.2 1.0 3.8e-68 230.2 1.0 3.0 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) PmrD PF11183.8 EAN33324.1 - 0.039 14.1 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD zf-NPL4 PF05020.15 EAN33325.1 - 0.042 14.0 0.1 0.086 13.0 0.1 1.5 1 0 0 1 1 1 0 NPL4 family, putative zinc binding region DUF2420 PF10336.9 EAN33326.1 - 0.039 14.0 0.5 0.069 13.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) DUF1281 PF06924.11 EAN33326.1 - 0.17 11.4 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) IMP2_N PF18590.1 EAN33327.1 - 1.9e-26 92.4 1.0 1.9e-26 92.4 1.0 2.4 3 1 0 3 3 3 1 Immune Mapped Protein 2 (IMP2) N-terminal domain B56 PF01603.20 EAN33328.1 - 2.7e-144 481.2 14.4 3.6e-144 480.8 14.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) V-SNARE_C PF12352.8 EAN33329.1 - 0.0011 19.2 0.8 0.053 13.8 0.0 3.2 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 EAN33329.1 - 0.0019 18.6 2.0 0.0019 18.6 2.0 2.2 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus EFP PF01132.20 EAN33329.1 - 0.15 12.1 0.0 24 5.1 0.0 2.7 3 0 0 3 3 3 0 Elongation factor P (EF-P) OB domain RRM_1 PF00076.22 EAN33330.1 - 5.2e-14 51.8 0.0 6.3e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 EAN33330.1 - 3e-10 40.0 4.1 6.9e-10 38.8 4.1 1.6 1 0 0 1 1 1 1 WW domain Nup35_RRM_2 PF14605.6 EAN33330.1 - 0.03 14.3 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TPR_14 PF13428.6 EAN33331.1 - 1.5e-05 25.4 4.4 64 4.8 0.0 8.3 7 2 2 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAN33331.1 - 2.4e-05 24.5 3.5 0.81 10.0 0.0 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAN33331.1 - 6.3e-05 22.9 13.4 0.21 11.9 0.1 7.8 9 0 0 9 9 9 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EAN33331.1 - 0.0043 17.0 15.0 0.0056 16.7 0.2 6.1 6 2 0 6 6 6 1 Mad3/BUB1 homology region 1 B PF02216.16 EAN33331.1 - 0.0053 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 B domain TPR_MalT PF17874.1 EAN33331.1 - 0.065 12.6 0.0 0.44 9.9 0.0 2.3 2 0 0 2 2 2 0 MalT-like TPR region Polyketide_cyc PF03364.20 EAN33331.1 - 0.07 13.3 1.1 0.14 12.4 0.3 1.9 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport 3H PF02829.14 EAN33331.1 - 0.12 12.7 0.1 0.43 10.9 0.1 1.9 1 0 0 1 1 1 0 3H domain TPR_2 PF07719.17 EAN33331.1 - 0.36 11.1 0.0 0.36 11.1 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Suf PF05843.14 EAN33331.1 - 3.2 7.7 15.2 3.8 7.4 1.1 4.5 5 0 0 5 5 5 0 Suppressor of forked protein (Suf) FAINT PF04385.15 EAN33332.1 - 2.9e-22 78.5 54.0 1.5e-07 31.3 1.3 6.8 6 0 0 6 6 6 6 Domain of unknown function, DUF529 MAPKK1_Int PF08923.10 EAN33333.1 - 0.046 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting COG5 PF10392.9 EAN33334.1 - 0.022 15.0 0.6 0.022 15.0 0.6 2.4 2 1 0 2 2 2 0 Golgi transport complex subunit 5 LEDGF PF11467.8 EAN33334.1 - 0.24 11.0 3.4 0.4 10.3 0.1 2.5 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) Peptidase_S66C PF17676.1 EAN33334.1 - 0.52 10.8 3.6 4.4 7.9 0.1 3.5 2 1 2 4 4 4 0 LD-carboxypeptidase C-terminal domain PNK3P PF08645.11 EAN33335.1 - 2.5e-54 183.3 0.0 3.2e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase DUF2729 PF10870.8 EAN33335.1 - 0.061 13.2 1.7 0.11 12.4 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2729) PXA PF02194.15 EAN33336.1 - 0.097 12.6 2.2 0.22 11.5 0.2 2.6 2 0 0 2 2 2 0 PXA domain COX2 PF00116.20 EAN33337.1 - 0.0021 17.9 0.3 0.0051 16.7 0.3 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Fe-S_assembly PF04384.13 EAN33338.1 - 7.5e-23 80.9 0.4 9.5e-23 80.6 0.4 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster assembly DUF3409 PF11889.8 EAN33339.1 - 0.08 12.9 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3409) Use1 PF09753.9 EAN33340.1 - 1.3e-05 25.1 6.0 5.1e-05 23.1 6.0 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF4795 PF16043.5 EAN33340.1 - 0.94 9.0 7.9 1.7 8.2 5.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Hydrolase_3 PF08282.12 EAN33342.1 - 6.8 6.4 9.0 10 5.8 7.7 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Sec23_trunk PF04811.15 EAN33343.1 - 9.2e-46 156.4 0.4 1.8e-45 155.4 0.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EAN33343.1 - 1.5e-19 70.5 0.5 6.6e-19 68.4 0.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EAN33343.1 - 2.4e-14 53.1 5.3 2.4e-14 53.1 5.3 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 EAN33343.1 - 0.00013 21.7 0.2 0.0003 20.6 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 EAN33343.1 - 0.00024 20.9 0.1 0.00063 19.6 0.1 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EAN33343.1 - 0.06 12.8 0.1 0.23 10.9 0.1 2.0 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA PF00092.28 EAN33343.1 - 0.062 13.6 0.1 16 5.7 0.1 3.0 3 0 0 3 3 3 0 von Willebrand factor type A domain FYVE_2 PF02318.16 EAN33343.1 - 0.73 10.1 4.5 0.54 10.5 0.4 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger PRMT5 PF05185.16 EAN33344.1 - 9.4e-54 181.9 0.0 4e-53 179.8 0.0 2.0 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EAN33344.1 - 9e-47 159.2 5.6 1.7e-46 158.3 5.6 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 EAN33344.1 - 2e-46 158.3 3.2 3e-46 157.7 2.4 1.7 2 0 0 2 2 2 1 PRMT5 TIM barrel domain Glycolytic PF00274.19 EAN33345.1 - 1.1e-152 507.8 0.4 1.3e-152 507.6 0.4 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I MutS_III PF05192.18 EAN33345.1 - 0.049 13.8 0.5 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 MutS domain III Prefoldin PF02996.17 EAN33346.1 - 4.4e-26 91.1 4.2 6e-26 90.7 4.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF4600 PF15372.6 EAN33346.1 - 0.0083 16.6 2.6 0.013 16.0 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4600) NPV_P10 PF05531.12 EAN33346.1 - 0.016 15.7 1.9 0.057 13.9 0.7 2.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5364 PF17322.2 EAN33346.1 - 0.025 14.9 1.0 0.043 14.1 1.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5364) ABC_tran_CTD PF16326.5 EAN33346.1 - 0.04 14.2 10.4 0.18 12.1 5.4 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 EAN33346.1 - 0.063 13.4 6.0 1 9.5 3.9 2.2 2 0 0 2 2 2 0 Tropomyosin like Prefoldin_2 PF01920.20 EAN33346.1 - 0.12 12.3 9.6 4.7 7.2 9.0 2.6 1 1 0 1 1 1 0 Prefoldin subunit DUF4635 PF15466.6 EAN33346.1 - 0.18 11.3 2.9 0.17 11.4 1.2 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4635) Trimer_CC PF08954.11 EAN33346.1 - 0.34 10.5 4.4 7.2 6.3 1.8 2.9 2 1 0 2 2 2 0 Trimerisation motif DUF5082 PF16888.5 EAN33346.1 - 0.45 10.8 6.5 8.4 6.7 6.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 EAN33346.1 - 1 9.6 6.6 7 6.8 1.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 EAN33346.1 - 1.6 9.2 7.6 2.9 8.4 3.3 2.1 1 1 0 2 2 2 0 Protein of unknown function DUF16 S6OS1 PF15676.5 EAN33346.1 - 2.1 6.7 6.6 0.42 9.0 2.6 1.7 2 0 0 2 2 2 0 Six6 opposite strand transcript 1 family GIT_CC PF16559.5 EAN33346.1 - 2.4 8.1 8.3 9.2 6.2 0.5 3.2 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.12 EAN33346.1 - 5.9 7.6 8.1 1.5 9.5 2.9 2.3 2 1 0 2 2 2 0 SlyX Cep57_MT_bd PF06657.13 EAN33346.1 - 9.9 6.7 13.2 19 5.8 0.4 3.2 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 HA2 PF04408.23 EAN33347.1 - 2.9e-11 43.6 0.0 5.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAN33347.1 - 9.6e-10 38.7 0.0 2.4e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAN33347.1 - 0.075 13.4 2.3 0.22 11.9 0.1 2.9 3 1 0 3 3 3 0 Helicase conserved C-terminal domain CtaG_Cox11 PF04442.14 EAN33348.1 - 9.3e-53 178.3 0.3 1.4e-52 177.7 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Synaptobrevin PF00957.21 EAN33349.1 - 6.3e-05 22.7 0.4 9.7e-05 22.1 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Mid2 PF04478.12 EAN33349.1 - 0.011 15.5 0.2 0.044 13.6 0.1 1.9 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor BP28CT PF08146.12 EAN33349.1 - 0.084 12.7 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 BP28CT (NUC211) domain DUF573 PF04504.14 EAN33350.1 - 0.3 11.8 2.0 0.45 11.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Kin17_mid PF10357.9 EAN33351.1 - 1.8e-44 150.6 3.0 4.6e-44 149.4 3.0 1.7 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 EAN33351.1 - 0.0026 17.9 0.1 0.0069 16.5 0.1 1.7 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain KOW PF00467.29 EAN33351.1 - 0.0037 17.2 0.1 0.01 15.7 0.1 1.8 1 0 0 1 1 1 1 KOW motif zf-met PF12874.7 EAN33351.1 - 0.0099 16.2 3.4 0.029 14.8 3.4 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EAN33351.1 - 0.014 15.7 5.0 0.046 14.0 5.0 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PTEN_C2 PF10409.9 EAN33351.1 - 0.02 14.6 0.3 0.039 13.7 0.3 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Ribonuc_red_2_N PF08471.10 EAN33351.1 - 0.057 13.6 1.5 0.16 12.2 1.3 1.8 1 1 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase DUF2540 PF10802.8 EAN33351.1 - 0.088 12.9 4.2 0.14 12.3 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) MDH PF02315.16 EAN33351.1 - 0.17 12.0 1.9 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit TetR_C_19 PF17924.1 EAN33351.1 - 0.18 12.4 4.7 0.18 12.4 0.2 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ISP3_C PF18045.1 EAN33352.1 - 4.4e-42 142.4 0.8 5.3e-42 142.1 0.8 1.1 1 0 0 1 1 1 1 ISP3 C-terminal ISP1_C PF18161.1 EAN33352.1 - 2.4e-37 127.2 0.7 3e-37 126.9 0.7 1.1 1 0 0 1 1 1 1 ISP1 C-terminal RBD-FIP PF09457.10 EAN33352.1 - 0.069 13.1 1.0 0.16 11.9 1.0 1.6 1 0 0 1 1 1 0 FIP domain TPR_8 PF13181.6 EAN33353.1 - 0.00027 20.9 0.1 0.43 10.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAN33353.1 - 0.0045 17.5 0.1 0.14 12.7 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAN33353.1 - 0.0052 16.8 0.0 21 5.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAN33353.1 - 0.0075 16.5 0.0 3.7 7.9 0.0 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAN33353.1 - 0.09 12.8 0.6 1.5 9.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SPOC PF07744.13 EAN33354.1 - 6e-10 39.2 0.0 1.7e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 EAN33354.1 - 9.3e-07 28.6 0.5 0.0087 15.9 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3848 PF12959.7 EAN33355.1 - 0.00055 20.0 2.9 0.17 11.9 0.2 3.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3848) PAC4 PF16093.5 EAN33356.1 - 5.6e-11 42.5 0.0 7.8e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 hnRNP_Q_AcD PF18360.1 EAN33356.1 - 0.02 14.9 0.1 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Methyltransf_5 PF01795.19 EAN33357.1 - 6.7e-68 229.5 0.0 3.2e-67 227.2 0.0 1.8 1 1 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 EAN33357.1 - 2.7e-05 24.0 0.0 0.0058 16.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Sec15 PF04091.12 EAN33357.1 - 0.019 14.4 0.5 4.9 6.5 0.1 2.2 2 0 0 2 2 2 0 Exocyst complex subunit Sec15-like PCMT PF01135.19 EAN33357.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EAN33357.1 - 0.035 14.8 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EAN33357.1 - 0.13 11.8 0.0 0.76 9.3 0.0 2.1 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Rotamase PF00639.21 EAN33358.1 - 3.7e-20 72.7 0.0 4.1e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EAN33358.1 - 1.6e-17 64.1 0.0 1.8e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EAN33358.1 - 1.6e-05 25.7 0.0 1.8e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain TAP42 PF04177.12 EAN33359.1 - 9e-27 94.0 8.0 1.2e-26 93.6 8.0 1.2 1 0 0 1 1 1 1 TAP42-like family Peptidase_M99_C PF17129.4 EAN33359.1 - 0.00022 21.4 0.3 0.002 18.3 0.1 2.5 2 1 0 2 2 2 1 C-terminal domain of metallo-carboxypeptidase Lactamase_B PF00753.27 EAN33361.1 - 6.5e-08 32.8 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAN33361.1 - 6.3e-07 29.1 0.0 9e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Glycos_transf_4 PF00953.21 EAN33362.1 - 1.8e-31 109.3 12.3 1.8e-31 109.3 12.3 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 4 Pigment_DH PF06324.11 EAN33362.1 - 0.11 12.6 0.6 0.67 10.2 0.6 2.4 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) AMP-binding PF00501.28 EAN33363.1 - 5.1e-72 242.8 0.0 7.4e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAN33363.1 - 8.7e-06 26.6 0.0 1.8e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SMC_N PF02463.19 EAN33364.1 - 5.8e-14 52.1 0.0 7.2e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAN33364.1 - 4.1e-12 47.0 0.1 5.2e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EAN33364.1 - 6.2e-05 22.9 0.7 6.7e-05 22.8 0.7 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EAN33364.1 - 0.00092 19.1 0.2 0.0013 18.6 0.2 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAN33364.1 - 0.0021 17.8 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EAN33364.1 - 0.0045 16.6 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain MNE1 PF13762.6 EAN33364.1 - 0.033 14.2 0.3 0.086 12.8 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component ABC_tran PF00005.27 EAN33364.1 - 0.043 14.3 0.0 0.061 13.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_13 PF13166.6 EAN33364.1 - 0.05 12.2 0.1 0.062 12.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 EAN33365.1 - 9.9e-05 21.4 22.2 0.024 13.6 8.4 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein DHR10 PF18595.1 EAN33365.1 - 0.0015 18.5 20.2 0.018 15.1 6.3 2.1 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain HrpB7 PF09486.10 EAN33365.1 - 0.0018 18.7 1.6 0.0043 17.5 1.5 1.5 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) SlyX PF04102.12 EAN33365.1 - 0.0021 18.7 5.9 0.022 15.4 0.6 2.4 2 1 0 2 2 2 1 SlyX LPP PF04728.13 EAN33365.1 - 0.0021 18.4 6.8 0.078 13.4 0.6 2.7 3 0 0 3 3 2 1 Lipoprotein leucine-zipper Sec2p PF06428.11 EAN33365.1 - 0.003 17.5 4.9 0.003 17.5 4.9 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Tektin PF03148.14 EAN33365.1 - 0.0043 15.9 7.5 0.0043 15.9 7.5 2.2 1 1 1 2 2 2 1 Tektin family Filament PF00038.21 EAN33365.1 - 0.0052 16.4 18.1 0.033 13.8 7.7 2.0 1 1 1 2 2 2 1 Intermediate filament protein ATG16 PF08614.11 EAN33365.1 - 0.0053 17.0 16.7 0.011 16.0 6.5 2.0 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF3573 PF12097.8 EAN33365.1 - 0.0072 15.2 8.2 0.098 11.5 1.5 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3573) Exonuc_VII_L PF02601.15 EAN33365.1 - 0.0094 15.5 11.4 0.012 15.3 11.4 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF3584 PF12128.8 EAN33365.1 - 0.01 13.4 16.3 0.011 13.3 16.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FliD_N PF02465.18 EAN33365.1 - 0.012 16.3 16.6 0.11 13.2 7.3 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus MscS_porin PF12795.7 EAN33365.1 - 0.013 15.1 13.8 0.015 14.9 13.8 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.9 EAN33365.1 - 0.014 15.4 24.9 0.069 13.2 22.4 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EAN33365.1 - 0.02 14.9 24.1 0.11 12.6 5.8 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 EAN33365.1 - 0.021 15.2 6.0 0.021 15.2 6.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Gon7 PF08738.10 EAN33365.1 - 0.026 14.6 4.3 0.026 14.6 4.3 2.2 1 1 1 2 2 2 0 Gon7 family Fez1 PF06818.15 EAN33365.1 - 0.026 15.0 18.6 0.2 12.1 16.0 2.0 1 1 1 2 2 2 0 Fez1 GAS PF13851.6 EAN33365.1 - 0.037 13.4 23.4 0.79 9.0 12.4 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 EAN33365.1 - 0.044 14.1 15.7 0.27 11.6 2.3 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MDM31_MDM32 PF08118.11 EAN33365.1 - 0.05 12.3 5.1 0.061 12.0 5.1 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins PspA_IM30 PF04012.12 EAN33365.1 - 0.052 13.1 14.0 0.28 10.7 3.2 2.2 1 1 0 2 2 2 0 PspA/IM30 family TolA_bind_tri PF16331.5 EAN33365.1 - 0.056 13.5 3.6 0.2 11.8 0.5 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation NPV_P10 PF05531.12 EAN33365.1 - 0.065 13.7 6.5 1.4 9.4 1.1 2.6 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 EAN33365.1 - 0.073 13.2 21.7 0.095 12.8 21.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF948 PF06103.11 EAN33365.1 - 0.12 12.6 2.4 0.4 11.0 0.9 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_7 PF13176.6 EAN33365.1 - 0.13 12.4 0.6 2.5 8.3 0.4 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat YlqD PF11068.8 EAN33365.1 - 0.13 12.6 14.7 0.22 11.9 1.2 2.3 1 1 1 2 2 2 0 YlqD protein MCPsignal PF00015.21 EAN33365.1 - 0.14 12.0 4.8 0.25 11.2 2.0 1.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FemAB PF02388.16 EAN33365.1 - 0.16 10.8 19.0 0.14 11.0 5.7 2.0 1 1 1 2 2 2 0 FemAB family Snapin_Pallidin PF14712.6 EAN33365.1 - 0.16 12.4 12.3 1.1 9.7 0.7 2.4 1 1 0 2 2 2 0 Snapin/Pallidin Atg14 PF10186.9 EAN33365.1 - 0.19 10.8 20.5 0.036 13.1 11.3 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Vir_act_alpha_C PF10400.9 EAN33365.1 - 0.21 12.3 4.0 7.7 7.3 1.1 2.6 2 1 0 2 2 2 0 Virulence activator alpha C-term DUF745 PF05335.13 EAN33365.1 - 0.27 10.9 10.8 0.37 10.5 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) CENP-Q PF13094.6 EAN33365.1 - 0.28 11.4 16.4 0.35 11.1 16.4 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4140 PF13600.6 EAN33365.1 - 0.36 11.3 10.9 2.8 8.4 1.9 3.1 2 2 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CorA PF01544.18 EAN33365.1 - 0.37 10.1 5.7 0.48 9.7 5.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2802 PF10975.8 EAN33365.1 - 0.4 10.8 5.9 2.5 8.3 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Cob_adeno_trans PF01923.18 EAN33365.1 - 0.42 10.7 7.5 1.4 9.1 0.9 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Spc24 PF08286.11 EAN33365.1 - 0.44 10.8 18.1 1.2 9.5 4.7 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DASH_Hsk3 PF08227.11 EAN33365.1 - 0.47 10.9 4.8 4.9 7.6 0.2 2.7 3 0 0 3 3 2 0 DASH complex subunit Hsk3 like DivIC PF04977.15 EAN33365.1 - 0.48 10.2 15.8 0.23 11.2 2.6 3.1 1 1 3 4 4 4 0 Septum formation initiator Uds1 PF15456.6 EAN33365.1 - 0.51 10.5 13.3 0.37 10.9 11.3 1.7 1 1 1 2 2 2 0 Up-regulated During Septation YvrJ PF12841.7 EAN33365.1 - 0.52 9.9 5.6 7.6 6.2 0.8 2.7 2 0 0 2 2 2 0 YvrJ protein family MIP-T3_C PF17749.1 EAN33365.1 - 0.57 10.1 15.1 1.8 8.5 13.7 2.1 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region V_ATPase_I PF01496.19 EAN33365.1 - 0.61 7.9 13.6 0.84 7.5 13.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family HemX PF04375.14 EAN33365.1 - 0.64 9.3 14.9 1.4 8.2 2.5 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase MPS2 PF17060.5 EAN33365.1 - 0.65 9.2 15.4 2.6 7.2 15.5 1.7 1 1 0 1 1 1 0 Monopolar spindle protein 2 PI3K_P85_iSH2 PF16454.5 EAN33365.1 - 0.69 9.5 17.8 0.94 9.1 17.8 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 EAN33365.1 - 0.76 9.8 9.9 9.3 6.3 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 EAN33365.1 - 0.8 9.4 21.5 3.7 7.3 9.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Tropomyosin_1 PF12718.7 EAN33365.1 - 0.97 9.6 24.5 0.44 10.7 8.8 2.3 1 1 1 2 2 2 0 Tropomyosin like Csm1_N PF18504.1 EAN33365.1 - 1.2 9.5 17.3 0.85 10.0 3.2 3.1 1 1 1 2 2 2 0 Csm1 N-terminal domain Jnk-SapK_ap_N PF09744.9 EAN33365.1 - 1.2 9.3 23.0 3 8.1 7.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4976 PF16347.5 EAN33365.1 - 1.3 9.3 7.6 0.33 11.2 3.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4976) Oxidored-like PF09791.9 EAN33365.1 - 1.3 8.7 3.4 17 5.2 0.3 2.4 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal MctB PF11382.8 EAN33365.1 - 1.4 8.6 4.3 6 6.5 0.4 2.1 1 1 0 2 2 2 0 Copper transport outer membrane protein, MctB GrpE PF01025.19 EAN33365.1 - 1.5 8.4 19.4 1.2 8.7 6.7 2.4 1 1 1 2 2 2 0 GrpE FlaC_arch PF05377.11 EAN33365.1 - 1.6 9.2 15.2 0.48 10.9 2.9 3.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) HXXSHH PF07586.11 EAN33365.1 - 1.7 8.2 6.6 12 5.4 6.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1552) DUF2564 PF10819.8 EAN33365.1 - 1.7 9.0 9.3 2.3 8.7 1.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF2564) Swi5 PF07061.11 EAN33365.1 - 1.9 8.6 20.2 0.13 12.3 3.4 3.2 1 1 2 3 3 3 0 Swi5 DUF349 PF03993.12 EAN33365.1 - 2 8.8 14.9 0.11 12.9 2.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Glutaredoxin2_C PF04399.13 EAN33365.1 - 2.6 7.9 9.9 1.1 9.1 3.0 2.1 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain DUF4349 PF14257.6 EAN33365.1 - 2.7 7.4 7.9 6.6 6.1 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Fib_alpha PF08702.10 EAN33365.1 - 2.8 8.1 14.8 2.2 8.5 13.1 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 EAN33365.1 - 2.9 8.1 19.5 1.6 9.0 5.0 2.2 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2203 PF09969.9 EAN33365.1 - 3.4 8.4 10.9 3.4 8.4 2.9 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FlxA PF14282.6 EAN33365.1 - 3.7 7.6 18.6 4.4 7.3 4.4 2.6 1 1 1 2 2 2 0 FlxA-like protein DUF4404 PF14357.6 EAN33365.1 - 4.1 8.1 13.1 7.7 7.2 4.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) JIP_LZII PF16471.5 EAN33365.1 - 4.1 7.7 16.4 1.5 9.0 1.8 2.9 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II DUF4407 PF14362.6 EAN33365.1 - 4.7 6.5 11.8 0.95 8.8 3.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Laminin_II PF06009.12 EAN33365.1 - 4.7 7.2 12.8 5.1 7.1 3.4 2.2 1 1 0 2 2 2 0 Laminin Domain II Prominin PF05478.11 EAN33365.1 - 5 4.9 13.5 7.9 4.3 13.5 1.4 1 1 0 1 1 1 0 Prominin MRP-L28 PF09812.9 EAN33365.1 - 6 7.0 15.4 7.2 6.7 15.4 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Prefoldin PF02996.17 EAN33365.1 - 7.5 6.5 19.4 0.86 9.5 1.6 3.7 1 1 2 4 4 4 0 Prefoldin subunit DUF2570 PF10828.8 EAN33365.1 - 9.4 6.1 11.7 3.8 7.4 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) APG6_N PF17675.1 EAN33366.1 - 0.0094 16.5 3.4 0.0094 16.5 3.4 4.3 3 1 1 4 4 4 1 Apg6 coiled-coil region DUF1732 PF08340.11 EAN33366.1 - 0.017 15.1 1.3 0.017 15.1 1.3 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1732) Sec34 PF04136.15 EAN33366.1 - 0.021 14.7 1.3 0.021 14.7 1.3 5.5 4 1 3 7 7 7 0 Sec34-like family FlaC_arch PF05377.11 EAN33366.1 - 0.033 14.6 1.9 0.033 14.6 1.9 6.5 6 1 1 8 8 8 0 Flagella accessory protein C (FlaC) OmpH PF03938.14 EAN33366.1 - 0.035 14.4 0.7 0.035 14.4 0.7 4.8 2 1 3 5 5 5 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.11 EAN33366.1 - 0.042 14.4 1.5 0.042 14.4 1.5 5.6 2 1 2 4 4 4 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 EAN33366.1 - 0.06 13.4 41.4 0.56 10.3 11.0 5.2 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein PI3K_P85_iSH2 PF16454.5 EAN33366.1 - 0.45 10.1 39.7 0.071 12.7 10.5 4.4 2 1 3 5 5 5 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain WXG100 PF06013.12 EAN33366.1 - 0.66 10.2 6.3 68 3.8 0.2 5.2 3 1 2 5 5 5 0 Proteins of 100 residues with WXG Myosin_tail_1 PF01576.19 EAN33366.1 - 1 7.1 33.7 0.37 8.6 0.5 2.7 2 1 0 2 2 2 0 Myosin tail DUF883 PF05957.13 EAN33366.1 - 1.4 9.6 10.5 5.1 7.8 0.3 4.6 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF883) Spc7 PF08317.11 EAN33366.1 - 3.7 6.3 44.4 0.17 10.7 2.3 4.2 2 1 2 4 4 4 0 Spc7 kinetochore protein TMPIT PF07851.13 EAN33366.1 - 6 6.0 32.5 0.31 10.2 0.2 4.4 2 1 3 5 5 5 0 TMPIT-like protein zf-C4H2 PF10146.9 EAN33366.1 - 6.9 6.9 39.3 0.077 13.3 16.3 3.8 2 1 1 3 3 3 0 Zinc finger-containing protein SMC_N PF02463.19 EAN33367.1 - 0.0018 17.7 0.1 0.0018 17.7 0.1 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Wyosine_form PF08608.12 EAN33369.1 - 3.5e-24 84.9 0.1 6.5e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 EAN33369.1 - 2.3e-18 67.1 0.1 4.6e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily RNA_pol_A_bac PF01000.26 EAN33370.1 - 2.6e-07 31.0 0.0 1e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EAN33370.1 - 0.00047 19.5 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_CTD PF03118.15 EAN33370.1 - 0.0053 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain ThiF PF00899.21 EAN33371.1 - 3.2e-61 206.8 0.0 4.5e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EAN33371.1 - 6.5e-13 49.1 0.7 1.6e-12 47.9 0.7 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EAN33371.1 - 2.4e-09 37.5 0.0 0.00012 22.1 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 EAN33371.1 - 0.00021 21.4 0.0 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EAN33371.1 - 0.00064 20.1 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 EAN33371.1 - 0.048 14.2 0.1 0.2 12.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EAN33371.1 - 0.082 13.2 0.1 0.31 11.3 0.1 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FG-GAP PF01839.23 EAN33371.1 - 0.095 12.9 0.9 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 FG-GAP repeat TrkA_N PF02254.18 EAN33371.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 EAN33371.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Myb_DNA-binding PF00249.31 EAN33372.1 - 2.5e-10 40.4 0.0 6.6e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAN33372.1 - 7.2e-07 29.4 0.0 2.3e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EAN33372.1 - 0.0014 18.4 15.3 0.0027 17.5 15.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Thioredoxin PF00085.20 EAN33373.1 - 8.8e-14 51.3 0.0 1e-11 44.8 0.0 3.6 3 1 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 EAN33373.1 - 1e-13 51.6 4.2 0.00015 21.8 2.3 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain Glutaredoxin PF00462.24 EAN33373.1 - 0.00085 19.5 0.0 0.0048 17.1 0.0 2.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 EAN33373.1 - 0.0019 18.3 0.0 0.007 16.5 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EAN33373.1 - 0.0051 16.7 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 EAN33373.1 - 0.034 13.8 0.0 0.93 9.2 0.0 2.3 2 0 0 2 2 2 0 Redoxin Thioredoxin_2 PF13098.6 EAN33373.1 - 0.051 14.0 0.0 0.16 12.4 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like domain FBA_2 PF07735.17 EAN33373.1 - 3.2 7.9 6.3 3.9 7.7 0.1 3.7 4 0 0 4 4 4 0 F-box associated Suf PF05843.14 EAN33374.1 - 1.2e-07 32.1 16.8 4e-06 27.0 5.5 4.0 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_8 PF13181.6 EAN33374.1 - 0.02 15.1 3.0 0.37 11.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAN33374.1 - 0.094 13.2 0.4 34 5.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAN33374.1 - 0.12 12.6 7.1 0.44 10.8 0.1 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3800 PF12686.7 EAN33374.1 - 0.13 12.8 0.2 2.2 8.9 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) TPR_14 PF13428.6 EAN33374.1 - 0.2 12.6 3.7 1.6e+02 3.6 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAN33374.1 - 0.65 10.3 7.4 15 6.0 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF760 PF05542.11 EAN33375.1 - 2.3e-24 85.6 0.9 3.1e-11 43.5 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF760) FAINT PF04385.15 EAN33377.1 - 1.2e-06 28.5 0.4 1.2e-06 28.5 0.4 4.1 4 1 0 4 4 4 2 Domain of unknown function, DUF529 Tmemb_cc2 PF10267.9 EAN33377.1 - 0.0057 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein ArdA PF07275.11 EAN33377.1 - 0.035 14.7 6.8 0.078 13.6 6.3 1.8 1 1 1 2 2 2 0 Antirestriction protein (ArdA) ArfGap PF01412.18 EAN33380.1 - 5.1e-37 126.5 0.1 2.2e-36 124.4 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf IMCp PF12314.8 EAN33381.1 - 7.1e-19 67.9 54.1 5.3e-14 52.3 28.1 2.1 1 1 1 2 2 2 2 Inner membrane complex protein Ribosomal_L32p PF01783.23 EAN33382.1 - 0.0071 16.6 6.6 0.014 15.7 6.6 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family SpoU_methylase PF00588.19 EAN33383.1 - 1e-05 25.7 0.0 1.8e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family WD40 PF00400.32 EAN33384.1 - 1.5e-09 38.3 14.3 0.023 15.6 0.1 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40_like PF17005.5 EAN33384.1 - 0.028 13.8 0.0 0.47 9.7 0.1 2.1 2 0 0 2 2 2 0 WD40-like domain CAF1C_H4-bd PF12265.8 EAN33385.1 - 9e-13 48.3 0.2 1.7e-12 47.4 0.2 1.4 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EAN33386.1 - 2.9e-07 31.1 2.5 0.17 12.8 0.0 3.6 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF4488 PF14869.6 EAN33387.1 - 0.024 14.5 0.1 0.072 13.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) tRNA-synt_His PF13393.6 EAN33389.1 - 1.8e-43 149.0 0.0 3.7e-43 147.9 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EAN33389.1 - 6.7e-12 45.4 0.0 2e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EAN33389.1 - 1.5e-07 31.2 0.1 3e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 EAN33389.1 - 0.0016 17.6 0.2 0.0085 15.2 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EAN33389.1 - 0.014 14.8 0.0 0.037 13.5 0.0 1.6 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) QIL1 PF15884.5 EAN33389.1 - 1.1 10.0 3.0 7.5 7.2 0.1 3.4 2 1 1 3 3 3 0 MICOS complex subunit MIC13, QIL1 DEAD PF00270.29 EAN33390.1 - 1.8e-33 115.7 0.1 4.9e-33 114.3 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN33390.1 - 8.3e-24 84.1 2.2 2.4e-22 79.4 0.4 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain OMS28_porin PF03532.13 EAN33390.1 - 0.041 13.1 0.5 0.11 11.8 0.5 1.6 1 0 0 1 1 1 0 OMS28 porin FSH1 PF03959.13 EAN33391.1 - 2.8e-47 161.1 0.0 5.1e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EAN33391.1 - 0.0091 15.8 0.1 0.093 12.5 0.0 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EAN33391.1 - 0.039 13.6 0.0 1.6 8.3 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold DAP3 PF10236.9 EAN33392.1 - 4e-24 85.3 0.0 6e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EAN33392.1 - 3.2e-05 24.4 0.0 5.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EAN33392.1 - 0.019 14.9 0.0 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 EAN33392.1 - 0.021 14.8 0.6 9.9 6.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EAN33392.1 - 0.13 12.6 0.0 1.4 9.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 EAN33393.1 - 2.2e-42 145.2 0.1 3.1e-42 144.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN33393.1 - 1.5e-19 70.3 0.0 2.5e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M16 PF00675.20 EAN33395.1 - 2.9e-44 150.7 0.0 4.9e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EAN33395.1 - 1.6e-23 83.7 1.3 6.4e-22 78.4 0.4 3.3 2 2 0 2 2 2 1 Peptidase M16 inactive domain CHCH PF06747.13 EAN33395.1 - 0.21 11.7 1.2 0.7 10.1 0.3 2.2 2 0 0 2 2 2 0 CHCH domain GCP_N_terminal PF17681.1 EAN33396.1 - 8.3e-19 68.3 2.8 1.8e-18 67.2 2.8 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Rho_GDI PF02115.17 EAN33396.1 - 0.013 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor Spc7 PF08317.11 EAN33397.1 - 0.00084 18.3 16.9 0.00084 18.3 16.9 4.3 1 1 4 5 5 5 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EAN33397.1 - 0.0066 16.5 15.5 0.0066 16.5 15.5 4.5 3 1 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 EAN33397.1 - 0.017 14.5 56.8 0.33 10.3 13.9 4.0 2 2 2 4 4 4 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 EAN33397.1 - 0.23 10.5 40.1 4.6 6.2 15.1 3.9 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4164 PF13747.6 EAN33397.1 - 1.2 9.4 22.4 0.76 10.1 1.6 4.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) ZapB PF06005.12 EAN33397.1 - 3 8.3 68.6 2.7 8.5 6.6 8.2 4 2 3 7 7 7 0 Cell division protein ZapB Cep57_MT_bd PF06657.13 EAN33397.1 - 3.9 8.0 18.2 0.39 11.2 2.4 4.4 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 FliJ PF02050.16 EAN33397.1 - 5.4 7.2 18.3 0.77 10.0 0.6 3.4 3 1 0 3 3 3 0 Flagellar FliJ protein SlyX PF04102.12 EAN33397.1 - 6 7.6 25.4 0.071 13.7 1.1 5.8 5 2 2 7 7 7 0 SlyX Helicase_C_2 PF13307.6 EAN33399.1 - 2.6e-40 138.4 0.0 6.6e-40 137.1 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EAN33399.1 - 2.1e-33 115.4 7.6 1.9e-29 102.5 2.6 3.8 1 1 1 2 2 2 2 DEAD_2 HBB PF06777.11 EAN33399.1 - 3e-25 89.0 0.8 2.8e-19 69.5 0.1 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 EAN33399.1 - 4e-10 39.9 0.0 6.6e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EAN33399.1 - 0.016 15.0 0.2 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase UBX PF00789.20 EAN33400.1 - 1.3e-16 60.6 0.1 2.6e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 UBX domain Glyco_transf_15 PF01793.16 EAN33400.1 - 0.025 13.9 2.6 0.04 13.2 2.6 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF4047 PF13256.6 EAN33400.1 - 0.23 11.7 5.6 2.7 8.2 5.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4047) DUF5511 PF17630.2 EAN33400.1 - 0.38 11.0 3.5 1.9 8.7 0.1 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5511) DUF4160 PF13711.6 EAN33400.1 - 2.9 8.3 6.0 1.6 9.1 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4160) ARID PF01388.21 EAN33401.1 - 2.1e-07 31.5 0.2 3.3e-06 27.7 0.0 2.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain MORN PF02493.20 EAN33402.1 - 1.1e-75 245.2 87.1 2.9e-07 30.0 1.4 12.1 12 0 0 12 12 12 12 MORN repeat Peptidase_S55 PF05580.12 EAN33402.1 - 0.07 13.1 4.6 4.4 7.2 0.1 3.9 3 2 2 5 5 5 0 SpoIVB peptidase S55 TetR_C_23 PF17931.1 EAN33403.1 - 0.0099 16.0 0.4 0.014 15.5 0.4 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF4062 PF13271.6 EAN33403.1 - 0.068 13.5 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) HCBP_related PF06594.11 EAN33403.1 - 1.3 9.0 4.0 1.4 8.9 0.2 2.5 2 1 0 2 2 2 0 Haemolysin-type calcium binding protein related domain Mpp10 PF04006.12 EAN33404.1 - 2.2e-37 128.8 47.4 3.9e-36 124.7 47.4 2.6 1 1 0 1 1 1 1 Mpp10 protein M157 PF11624.8 EAN33404.1 - 0.013 14.8 1.8 0.025 13.9 1.8 1.4 1 0 0 1 1 1 0 MHC class I-like protein M157 tRNA-synt_2b PF00587.25 EAN33405.1 - 2e-18 67.0 0.0 3.4e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EAN33405.1 - 0.016 15.5 0.2 0.031 14.5 0.2 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Pox_A_type_inc PF04508.12 EAN33405.1 - 0.15 11.9 0.2 0.56 10.1 0.2 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SRP19 PF01922.17 EAN33407.1 - 7.7e-30 103.7 0.3 7.7e-30 103.7 0.3 1.4 2 0 0 2 2 2 1 SRP19 protein Peptidase_C74 PF12387.8 EAN33407.1 - 0.032 13.7 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Pestivirus NS2 peptidase PNGaseA PF12222.8 EAN33407.1 - 0.056 12.3 0.2 0.067 12.0 0.2 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A MACPF PF01823.19 EAN33408.1 - 8.8e-50 169.7 2.1 2.1e-49 168.5 2.1 1.7 1 0 0 1 1 1 1 MAC/Perforin domain tRNA_edit PF04073.15 EAN33410.1 - 3.2e-23 82.1 0.0 5.2e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.25 EAN33410.1 - 4.5e-23 82.1 0.0 1e-22 81.0 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EAN33410.1 - 1.2e-20 73.4 0.0 3.6e-20 71.9 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain GhoS PF11080.8 EAN33410.1 - 0.062 13.3 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 0 Endoribonuclease GhoS CpcD PF01383.21 EAN33410.1 - 0.097 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain Hexapep PF00132.24 EAN33411.1 - 0.0002 21.0 17.9 0.0066 16.1 2.8 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) TCP PF03634.13 EAN33411.1 - 0.084 13.4 0.7 4 8.0 0.1 2.5 2 0 0 2 2 2 0 TCP family transcription factor W2 PF02020.18 EAN33411.1 - 0.27 11.4 3.5 0.22 11.7 0.6 2.2 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Fucokinase PF07959.12 EAN33411.1 - 0.31 10.0 6.1 0.052 12.5 2.0 1.8 2 0 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 EAN33411.1 - 1.9 6.5 12.6 0.041 12.0 5.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EAN33411.1 - 3.7 7.4 15.9 1.4 8.7 5.2 3.4 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase BCNT PF07572.12 EAN33412.1 - 0.029 14.4 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 Bucentaur or craniofacial development Emaravirus_P4 PF16505.5 EAN33412.1 - 0.05 12.6 0.4 0.062 12.3 0.4 1.1 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily SpoVAC_SpoVAEB PF03862.13 EAN33413.1 - 0.015 15.6 0.1 0.024 14.9 0.1 1.3 1 0 0 1 1 1 0 SpoVAC/SpoVAEB sporulation membrane protein Phosphodiest PF01663.22 EAN33414.1 - 0.00045 19.9 0.0 0.00068 19.3 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF5601 PF18151.1 EAN33414.1 - 0.031 14.6 0.2 0.096 13.0 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) Sulfatase PF00884.23 EAN33414.1 - 0.095 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Sulfatase Prenyltrans PF00432.21 EAN33415.1 - 2e-20 72.2 0.8 4.8e-05 23.0 0.0 5.5 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat LON_substr_bdg PF02190.16 EAN33415.1 - 0.047 13.6 0.0 0.26 11.1 0.0 1.9 1 1 1 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain TRF PF08558.10 EAN33416.1 - 0.0051 16.4 0.0 0.0061 16.2 0.0 1.0 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Fer2 PF00111.27 EAN33417.1 - 7e-10 38.7 1.5 9.8e-10 38.3 1.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NifU PF01106.17 EAN33417.1 - 0.17 12.1 0.8 0.5 10.6 0.1 2.0 2 0 0 2 2 2 0 NifU-like domain MCR PF18509.1 EAN33417.1 - 0.72 9.5 5.3 0.34 10.5 2.5 1.9 1 1 1 2 2 2 0 Magnetochrome domain ETRAMP PF09716.10 EAN33419.1 - 0.079 13.0 3.0 0.23 11.5 3.0 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TauE PF01925.19 EAN33420.1 - 0.00071 19.3 7.1 0.00071 19.3 7.1 1.4 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE PSII PF00421.19 EAN33420.1 - 0.22 10.2 4.6 0.61 8.7 3.4 1.8 1 1 1 2 2 2 0 Photosystem II protein Phage_holin_5_2 PF16079.5 EAN33420.1 - 0.24 11.7 0.0 0.24 11.7 0.0 3.3 1 1 3 4 4 4 0 Phage holin family Hol44, in holin superfamily V DUF1072 PF06380.11 EAN33420.1 - 0.56 10.1 3.9 1.2 9.0 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) DUF4233 PF14017.6 EAN33420.1 - 0.66 10.3 6.3 0.1 13.0 0.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4233) Polysacc_synt_C PF14667.6 EAN33420.1 - 0.71 9.9 15.1 0.45 10.6 2.6 2.4 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Gram_pos_anchor PF00746.21 EAN33420.1 - 3.4 7.7 0.0 3.4 7.7 0.0 3.5 5 0 0 5 5 5 0 LPXTG cell wall anchor motif GNVR PF13807.6 EAN33420.1 - 5.5 7.0 5.2 1.9 8.4 0.1 2.9 3 1 1 4 4 4 0 G-rich domain on putative tyrosine kinase AhpC-TSA PF00578.21 EAN33421.1 - 2.8e-29 101.6 0.0 3.9e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAN33421.1 - 1.2e-13 51.1 0.0 1.7e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EAN33421.1 - 1.3e-11 44.1 1.0 1.7e-11 43.7 0.2 1.6 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin FAINT PF04385.15 EAN33422.1 - 1.1e-15 57.4 0.2 1.5e-06 28.2 0.8 3.2 2 0 0 2 2 2 2 Domain of unknown function, DUF529 LegC3_N PF18654.1 EAN33422.1 - 0.8 8.9 5.9 1.4 8.1 5.9 1.3 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain HTH_Tnp_Mu_1 PF02316.16 EAN33423.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Mu DNA-binding domain Ribosomal_S11 PF00411.19 EAN33424.1 - 0.00051 20.4 0.1 0.00077 19.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L18p PF00861.22 EAN33424.1 - 0.00088 19.6 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Utp12 PF04003.12 EAN33425.1 - 8.7e-17 61.4 0.5 1.2e-16 60.9 0.5 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF1951 PF09188.10 EAN33425.1 - 0.049 13.6 0.0 0.16 11.9 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1951) CLTH PF10607.9 EAN33426.1 - 2.3e-23 82.7 6.8 2.3e-23 82.7 6.8 1.4 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Utp11 PF03998.13 EAN33427.1 - 2.4e-25 89.9 21.9 3.6e-25 89.3 21.9 1.3 1 1 0 1 1 1 1 Utp11 protein tRNA_int_endo PF01974.17 EAN33428.1 - 2.3e-11 43.6 0.1 2.6e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain MutS_V PF00488.21 EAN33429.1 - 2.4e-69 233.1 0.8 4.6e-69 232.2 0.8 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EAN33429.1 - 1.6e-35 123.1 0.2 7e-35 121.0 0.1 2.2 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EAN33429.1 - 9.5e-30 103.1 0.0 2.6e-29 101.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain I AAA_23 PF13476.6 EAN33429.1 - 0.041 14.4 0.4 0.041 14.4 0.4 2.6 2 2 0 2 2 2 0 AAA domain TPR_19 PF14559.6 EAN33430.1 - 1.7e-08 34.8 0.4 0.078 13.5 0.0 6.0 5 2 0 6 6 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EAN33430.1 - 1e-07 32.0 12.6 0.00055 19.9 0.4 5.1 4 1 1 5 5 5 3 Putative TPR-like repeat TPR_14 PF13428.6 EAN33430.1 - 7.4e-06 26.4 0.1 8.3 7.5 0.0 5.1 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAN33430.1 - 8.5e-06 25.9 25.7 0.58 10.4 1.9 6.3 6 1 1 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EAN33430.1 - 0.0077 16.2 5.4 3.7 7.8 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAN33430.1 - 0.011 16.1 7.5 14 6.0 0.0 6.0 7 1 1 8 8 8 0 Tetratricopeptide repeat DUF2225 PF09986.9 EAN33430.1 - 0.028 14.1 3.6 0.36 10.5 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.17 EAN33430.1 - 0.041 14.0 22.1 5.9 7.3 0.1 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAN33430.1 - 0.097 13.4 8.1 40 5.2 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAN33430.1 - 1.2 9.1 13.9 18 5.3 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAN33430.1 - 2.4 8.6 19.1 56 4.3 0.1 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat Proteasome PF00227.26 EAN33431.1 - 8.2e-36 123.3 0.0 1e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Band_7 PF01145.25 EAN33432.1 - 1.4e-23 83.8 1.4 2e-23 83.3 0.4 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EAN33432.1 - 0.0055 15.8 0.9 0.0072 15.4 0.9 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Antigen_C PF16364.5 EAN33432.1 - 0.0072 16.7 0.4 0.011 16.2 0.4 1.2 1 0 0 1 1 1 1 Cell surface antigen C-terminus Lactamase_B_2 PF12706.7 EAN33433.1 - 2.1e-14 53.5 0.0 2.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EAN33433.1 - 7.7e-11 42.1 0.0 1.1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Cpn10 PF00166.21 EAN33434.1 - 7.4e-28 96.5 0.1 8.1e-28 96.3 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pro_isomerase PF00160.21 EAN33435.1 - 3e-19 69.9 0.0 4e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NifU_N PF01592.16 EAN33436.1 - 1.2e-48 164.5 0.3 1.9e-48 163.8 0.3 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain RNase_P_Rpp14 PF01900.19 EAN33436.1 - 1e-12 48.1 0.0 3.6e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Rpp14/Pop5 family 6PGD PF00393.19 EAN33437.1 - 4e-44 151.1 0.0 6.6e-24 84.8 0.0 2.1 1 1 1 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EAN33437.1 - 1.8e-31 109.4 0.0 2.9e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EAN33437.1 - 0.00014 21.9 0.0 0.00084 19.3 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 EAN33437.1 - 0.0055 16.8 0.0 0.015 15.3 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EAN33437.1 - 0.0078 16.1 0.0 0.018 14.9 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EAN33437.1 - 0.0091 15.4 0.0 0.03 13.7 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAZ_siRNAbind PF12212.8 EAN33437.1 - 0.011 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 PAZ domain ApbA PF02558.16 EAN33437.1 - 0.016 14.8 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EAN33437.1 - 0.05 14.2 0.0 0.089 13.4 0.0 1.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Actin PF00022.19 EAN33438.1 - 2.3e-47 161.5 0.0 8.7e-47 159.6 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EAN33438.1 - 0.00048 19.1 0.1 0.0014 17.6 0.1 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EAN33438.1 - 0.0067 16.8 0.5 0.027 14.9 0.2 2.1 2 1 0 2 2 2 1 Cell division protein FtsA Spem1 PF15670.5 EAN33440.1 - 1.2 8.7 8.3 2 7.9 8.3 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF4551 PF15087.6 EAN33440.1 - 3.4 6.4 14.4 5.5 5.7 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ALMT PF11744.8 EAN33440.1 - 3.9 6.2 9.0 8.1 5.2 9.0 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter MMR_HSR1 PF01926.23 EAN33441.1 - 1.6e-16 60.4 0.0 2.5e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAN33441.1 - 7.2e-09 35.4 0.0 0.0001 21.9 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAN33441.1 - 6.6e-07 29.4 0.0 0.0024 17.8 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAN33441.1 - 2.3e-05 24.1 0.0 0.00064 19.3 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EAN33441.1 - 7.6e-05 22.8 0.1 0.15 12.1 0.3 2.3 1 1 1 2 2 2 2 Dynamin family Septin PF00735.18 EAN33441.1 - 0.0038 16.6 0.0 0.072 12.4 0.0 2.1 2 0 0 2 2 2 1 Septin AIG1 PF04548.16 EAN33441.1 - 0.16 11.3 0.1 0.25 10.6 0.1 1.7 1 1 0 1 1 1 0 AIG1 family Roc PF08477.13 EAN33441.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RasGAP PF00616.19 EAN33442.1 - 0.092 12.4 6.7 0.15 11.7 6.8 1.5 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Ribosomal_L13e PF01294.18 EAN33443.1 - 5.9e-61 205.4 4.7 7.2e-61 205.2 4.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.19 EAN33444.1 - 4.1e-29 101.6 0.2 4.7e-29 101.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 ATP-synt PF00231.19 EAN33445.1 - 1.1e-81 274.7 4.1 1.2e-81 274.5 4.1 1.0 1 0 0 1 1 1 1 ATP synthase Cyc-maltodext_C PF10438.9 EAN33445.1 - 0.11 12.5 0.4 0.36 10.9 0.1 1.9 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain WD40 PF00400.32 EAN33446.1 - 9.9e-26 89.5 9.4 3.8e-07 30.7 0.1 5.9 5 1 0 5 5 5 4 WD domain, G-beta repeat LisH_TPL PF17814.1 EAN33446.1 - 6.6e-11 41.7 0.1 1.7e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 LisH-like dimerisation domain ANAPC4_WD40 PF12894.7 EAN33446.1 - 2.2e-09 37.5 0.1 0.00033 20.9 0.1 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAN33446.1 - 2.4e-06 26.8 1.0 0.066 12.2 0.0 4.1 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EAN33446.1 - 7.8e-05 21.5 0.4 0.021 13.5 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EAN33446.1 - 8.6e-05 22.5 0.1 0.071 13.0 0.0 3.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EAN33446.1 - 0.052 13.5 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 LisH Vps16_N PF04841.13 EAN33446.1 - 0.065 12.0 0.0 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 Vps16, N-terminal region RrnaAD PF00398.20 EAN33446.1 - 0.11 11.6 0.2 13 4.8 0.0 3.0 3 0 0 3 3 3 0 Ribosomal RNA adenine dimethylase Ndc80_HEC PF03801.13 EAN33447.1 - 1.5e-18 66.9 1.2 1.9e-18 66.6 1.2 1.1 1 0 0 1 1 1 1 HEC/Ndc80p family DUF4201 PF13870.6 EAN33448.1 - 0.013 15.3 2.1 0.015 15.1 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) CwfJ_C_2 PF04676.14 EAN33448.1 - 0.038 14.9 0.1 0.044 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 SNARE PF05739.19 EAN33449.1 - 0.16 12.0 1.0 0.49 10.4 0.2 2.0 2 0 0 2 2 2 0 SNARE domain DUF883 PF05957.13 EAN33449.1 - 0.53 10.9 2.8 0.45 11.1 0.8 1.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) MamL-1 PF09596.10 EAN33450.1 - 0.15 12.4 1.7 0.29 11.4 0.5 2.2 2 0 0 2 2 2 0 MamL-1 domain DUF1674 PF07896.12 EAN33451.1 - 3.5e-05 24.2 0.0 6.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) zf-C2HC PF01530.18 EAN33452.1 - 0.25 11.6 0.2 0.5 10.6 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2HC type Bromodomain PF00439.25 EAN33453.1 - 1.1e-16 60.6 2.3 3.2e-16 59.2 0.1 2.8 3 0 0 3 3 3 1 Bromodomain Fer2_3 PF13085.6 EAN33454.1 - 1e-34 118.8 0.0 1.8e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EAN33454.1 - 4e-10 40.1 4.9 4e-10 40.1 4.9 2.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EAN33454.1 - 1.2e-07 31.7 2.9 1.2e-07 31.7 2.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EAN33454.1 - 3.1e-07 30.7 23.7 1.4e-06 28.6 8.2 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 EAN33454.1 - 0.0019 18.1 0.3 0.0019 18.1 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 EAN33454.1 - 0.002 18.3 0.7 0.38 11.0 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EAN33454.1 - 0.011 16.3 8.5 0.011 16.3 8.5 3.0 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EAN33454.1 - 0.25 11.5 13.2 0.12 12.5 8.0 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 EAN33454.1 - 1.3 10.0 13.7 2.8 8.9 9.3 2.9 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain Spermine_synth PF01564.17 EAN33455.1 - 0.028 13.8 0.0 0.084 12.3 0.0 1.7 1 1 1 2 2 2 0 Spermine/spermidine synthase domain DEAD PF00270.29 EAN33456.1 - 7e-20 71.5 0.0 5.2e-09 36.1 0.0 2.6 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN33456.1 - 2.7e-15 56.7 1.5 5.3e-15 55.7 0.4 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN33456.1 - 0.00011 22.3 1.6 0.0026 17.8 0.1 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Methyltransf_11 PF08241.12 EAN33456.1 - 0.0016 19.1 0.0 0.0049 17.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAN33456.1 - 0.0034 18.1 0.0 0.01 16.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAN33456.1 - 0.0059 16.4 0.1 0.042 13.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAN33456.1 - 0.01 15.7 0.0 0.7 9.7 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 EAN33456.1 - 0.016 15.9 0.0 0.078 13.7 0.0 2.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EAN33456.1 - 0.034 14.1 1.2 0.073 13.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MgtE_N PF03448.17 EAN33456.1 - 0.27 11.8 2.1 0.48 11.1 0.3 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain RF-1 PF00472.20 EAN33457.1 - 6.2e-19 68.0 4.4 9e-19 67.5 4.4 1.2 1 0 0 1 1 1 1 RF-1 domain Ly49 PF08391.10 EAN33457.1 - 4.1 7.8 9.0 25 5.2 0.1 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region BCIP PF13862.6 EAN33458.1 - 1.6e-43 148.9 3.4 2.2e-43 148.4 3.4 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Pkinase PF00069.25 EAN33460.1 - 0.0013 18.2 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN33460.1 - 0.033 13.5 0.1 0.038 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4116 PF13475.6 EAN33460.1 - 0.069 12.9 0.6 0.57 9.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4116) DUF2717 PF10911.8 EAN33460.1 - 0.16 11.7 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) CNH PF00780.22 EAN33461.1 - 1.7e-06 27.8 0.2 3.6e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.9 EAN33462.1 - 3.6e-09 37.1 1.8 7.3e-09 36.1 0.0 2.3 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 EAN33462.1 - 6.2e-07 29.4 1.7 1.9e-05 24.5 1.5 2.6 1 1 0 1 1 1 1 Region in Clathrin and VPS YodL PF14191.6 EAN33462.1 - 0.051 14.4 0.1 0.16 12.9 0.0 2.0 2 0 0 2 2 2 0 YodL-like EF-hand_7 PF13499.6 EAN33463.1 - 6.6e-28 97.0 8.7 3.9e-11 43.2 1.1 4.6 3 1 1 4 4 4 3 EF-hand domain pair Metallophos PF00149.28 EAN33463.1 - 4.5e-24 86.1 0.3 1.4e-23 84.5 0.1 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.6 EAN33463.1 - 5.5e-17 60.2 6.9 0.016 15.1 0.3 6.5 6 0 0 6 6 6 5 EF-hand domain EF-hand_1 PF00036.32 EAN33463.1 - 3.4e-16 57.5 4.0 0.024 14.1 0.1 6.8 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.6 EAN33463.1 - 6.3e-11 42.0 7.6 0.002 17.9 0.1 5.4 4 2 2 6 6 6 4 EF-hand domain pair CAP_GLY PF01302.25 EAN33463.1 - 1e-06 28.7 0.1 2.7e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 CAP-Gly domain IQ PF00612.27 EAN33463.1 - 0.0028 17.3 0.3 0.0066 16.1 0.3 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_5 PF13202.6 EAN33463.1 - 0.0089 15.5 2.7 3 7.5 0.1 3.9 4 0 0 4 4 4 2 EF hand Utp21 PF04192.12 EAN33463.1 - 0.019 14.5 1.5 0.075 12.5 1.0 2.0 1 1 1 2 2 2 0 Utp21 specific WD40 associated putative domain TMEM208_SND2 PF05620.11 EAN33464.1 - 2.3e-09 37.2 1.5 5.6e-07 29.5 1.5 2.2 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 TPR_2 PF07719.17 EAN33465.1 - 2.2e-08 33.6 0.3 0.13 12.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAN33465.1 - 9.5e-08 31.6 2.7 0.0073 16.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAN33465.1 - 2.1e-06 27.7 3.5 0.0025 17.8 0.5 2.4 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 EAN33465.1 - 1e-05 25.3 2.9 0.039 14.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAN33465.1 - 0.00024 20.7 0.1 0.013 15.1 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 EAN33465.1 - 0.0027 18.2 0.0 0.0054 17.2 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Acyltransferase PF01553.21 EAN33466.1 - 7.5e-16 58.0 0.0 3e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase RseC_MucC PF04246.12 EAN33466.1 - 1.7 8.6 4.8 1.2 9.1 0.1 2.6 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Rsm22 PF09243.10 EAN33467.1 - 5.6e-43 147.2 0.4 3.5e-35 121.6 0.1 2.3 1 1 1 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 AhpC-TSA PF00578.21 EAN33468.1 - 3.5e-18 65.7 0.0 4.3e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAN33468.1 - 1.5e-13 50.7 0.0 1.8e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin SHS2_Rpb7-N PF03876.17 EAN33469.1 - 6.5e-16 58.5 0.0 1.1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EAN33469.1 - 8.6e-11 42.0 0.0 1.4e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF3783 PF12646.7 EAN33469.1 - 0.11 12.4 0.0 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) EF-hand_1 PF00036.32 EAN33471.1 - 2.2e-18 64.4 12.9 1.3e-05 24.4 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAN33471.1 - 5.2e-18 65.3 9.7 2.5e-11 43.8 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAN33471.1 - 1.8e-15 55.4 9.9 1.9e-05 24.2 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EAN33471.1 - 1e-10 41.3 15.0 7.3e-06 25.7 0.3 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EAN33471.1 - 2e-06 28.0 0.2 0.0045 17.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EAN33471.1 - 0.0011 18.4 7.9 9.1 6.0 0.1 4.7 4 1 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 EAN33471.1 - 0.0032 17.4 4.5 0.13 12.2 0.1 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand HTH_40 PF14493.6 EAN33471.1 - 0.011 16.1 0.2 1.1 9.7 0.1 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain SurA_N_3 PF13624.6 EAN33471.1 - 0.048 13.4 0.2 0.087 12.6 0.1 1.5 2 0 0 2 2 2 0 SurA N-terminal domain SurA_N_2 PF13623.6 EAN33471.1 - 0.058 13.2 0.2 0.39 10.6 0.1 2.1 2 1 0 2 2 2 0 SurA N-terminal domain Caleosin PF05042.13 EAN33471.1 - 0.069 13.1 1.6 6.8 6.6 0.0 3.0 1 1 3 4 4 4 0 Caleosin related protein NUFIP2 PF15293.6 EAN33471.1 - 0.07 12.0 0.1 0.076 11.9 0.1 1.1 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 EF-hand_14 PF17959.1 EAN33471.1 - 0.084 13.2 2.4 7.6 7.0 0.2 2.4 2 1 0 2 2 2 0 EF-hand domain Tubulin_3 PF14881.6 EAN33471.1 - 0.24 11.0 1.4 0.36 10.5 1.4 1.4 1 0 0 1 1 1 0 Tubulin domain DUF3911 PF13050.6 EAN33471.1 - 0.32 11.1 3.2 1.4 9.1 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3911) DUF908 PF06012.12 EAN33472.1 - 1.1e-17 64.5 6.5 7.2e-16 58.5 6.5 2.1 1 1 0 1 1 1 1 Domain of Unknown Function (DUF908) HECT PF00632.25 EAN33473.1 - 9.3e-90 301.2 0.1 1.9e-89 300.2 0.1 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 EAN33473.1 - 1.5e-44 152.5 0.1 1.5e-44 152.5 0.1 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) UBM PF14377.6 EAN33473.1 - 4.4e-11 41.8 1.5 0.00012 21.4 0.2 4.1 3 0 0 3 3 3 3 Ubiquitin binding region GAGA_bind PF06217.12 EAN33474.1 - 0.088 13.1 9.9 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Sof1 PF04158.14 EAN33475.1 - 1.2e-25 89.6 6.8 1.9e-25 89.0 6.8 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EAN33475.1 - 9.9e-20 70.5 6.9 0.00078 20.2 0.2 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN33475.1 - 0.0012 19.1 0.0 8.8 6.7 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Str_synth PF03088.16 EAN33475.1 - 0.15 12.2 0.5 0.97 9.6 0.0 2.5 4 0 0 4 4 4 0 Strictosidine synthase CelTOS PF18659.1 EAN33476.1 - 4.8e-50 169.1 0.6 6.2e-50 168.7 0.6 1.1 1 0 0 1 1 1 1 Cell-traversal protein for ookinetes and sporozoites ATP-synt_E_2 PF08112.11 EAN33476.1 - 0.012 15.9 1.6 0.023 14.9 1.6 1.5 1 0 0 1 1 1 0 ATP synthase epsilon subunit DNA_pol_phi PF04931.13 EAN33476.1 - 0.075 11.1 3.6 2.4 6.2 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase phi RNA_pol_Rpb8 PF03870.15 EAN33477.1 - 2.1e-37 128.4 0.3 2.4e-37 128.2 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EAN33477.1 - 7.7e-05 22.7 0.1 0.0012 18.8 0.1 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase, subunit G RBB1NT PF08169.11 EAN33477.1 - 0.035 14.2 0.1 0.097 12.8 0.1 1.7 2 0 0 2 2 2 0 RBB1NT (NUC162) domain Dynein_light PF01221.18 EAN33478.1 - 8.5e-37 125.3 2.2 9.6e-37 125.2 2.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 PCI PF01399.27 EAN33479.1 - 3.8e-05 24.2 0.0 3.8e-05 24.2 0.0 3.8 4 3 1 5 5 5 1 PCI domain Caldesmon PF02029.15 EAN33479.1 - 0.00021 20.2 14.3 0.00021 20.2 14.3 3.2 2 1 1 3 3 3 1 Caldesmon S1 PF00575.23 EAN33480.1 - 2.7e-15 56.5 5.6 1.5e-05 25.2 0.0 6.4 6 1 0 6 6 6 5 S1 RNA binding domain TPR_19 PF14559.6 EAN33481.1 - 8.4e-08 32.6 0.0 0.0034 17.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAN33481.1 - 8.8e-06 26.1 0.0 0.067 14.0 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAN33481.1 - 7.7e-05 22.6 0.9 0.9 9.9 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 EAN33481.1 - 0.00015 21.9 18.2 0.0024 17.9 0.7 3.7 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_15 PF13429.6 EAN33481.1 - 0.00086 18.6 0.1 0.66 9.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat NRDE-2 PF08424.10 EAN33481.1 - 0.0023 17.1 9.0 0.026 13.7 1.3 3.6 1 1 1 3 3 3 1 NRDE-2, necessary for RNA interference PKcGMP_CC PF16808.5 EAN33481.1 - 0.014 15.2 2.3 0.075 12.9 2.3 2.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TPR_1 PF00515.28 EAN33481.1 - 0.026 14.3 0.1 0.65 9.9 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 EAN33481.1 - 1.7 9.0 4.4 3.6 8.1 0.1 3.5 4 0 0 4 4 4 0 PPR repeat RRM_1 PF00076.22 EAN33482.1 - 4.5e-15 55.2 0.0 7.9e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAN33482.1 - 0.002 18.2 0.0 0.0055 16.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif CagY_I PF14585.6 EAN33482.1 - 0.7 10.0 7.1 1.3 9.1 7.1 1.4 1 0 0 1 1 1 0 CagY type 1 repeat EIF4E-T PF10477.9 EAN33482.1 - 1.3 7.7 30.3 1.8 7.3 30.3 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E zf-CCCH_4 PF18044.1 EAN33484.1 - 1.7e-07 30.9 0.7 4.7e-07 29.4 0.7 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EAN33484.1 - 3.6e-05 23.6 0.2 0.00012 21.9 0.2 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAN33484.1 - 0.00025 21.0 3.2 0.00025 21.0 3.2 2.1 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 EAN33484.1 - 0.008 16.9 0.4 0.018 15.7 0.4 1.5 1 0 0 1 1 1 1 Torus domain WD40 PF00400.32 EAN33484.1 - 0.016 16.0 9.1 5 8.2 1.2 5.1 5 1 0 5 5 5 0 WD domain, G-beta repeat zf-CCCH_2 PF14608.6 EAN33484.1 - 0.046 14.2 2.5 0.046 14.2 2.5 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RAB3GAP2_N PF14655.6 EAN33484.1 - 0.046 13.0 0.2 0.15 11.3 0.1 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cpn60_TCP1 PF00118.24 EAN33485.1 - 5.6e-151 503.5 18.4 6.4e-151 503.3 18.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Utp21 PF04192.12 EAN33486.1 - 8e-44 149.9 11.2 1.3e-43 149.2 11.2 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 EAN33486.1 - 4e-09 36.6 0.3 0.29 11.4 0.0 5.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAN33486.1 - 0.0074 17.1 3.1 32 5.6 0.1 5.5 5 0 0 5 5 5 0 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 EAN33486.1 - 0.0083 15.4 2.0 1.3 8.2 0.1 3.7 3 1 1 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Lgl_C PF08596.10 EAN33486.1 - 0.014 14.2 0.4 0.041 12.6 0.1 1.9 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal BBS1 PF14779.6 EAN33486.1 - 0.037 13.5 0.4 0.27 10.6 0.0 2.5 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 1 AF0941-like PF14591.6 EAN33486.1 - 0.32 11.6 1.9 11 6.7 0.2 2.8 2 0 0 2 2 2 0 AF0941-like CPSF_A PF03178.15 EAN33487.1 - 3.6e-32 111.9 9.3 2.2e-24 86.3 2.0 3.5 3 0 0 3 3 3 3 CPSF A subunit region MMS1_N PF10433.9 EAN33487.1 - 1.2e-18 67.1 8.2 5.9e-13 48.3 1.4 4.1 3 1 0 3 3 3 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pro_isomerase PF00160.21 EAN33488.1 - 2.7e-48 164.2 0.2 3.8e-48 163.7 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD mRNA_triPase PF02940.15 EAN33489.1 - 2.9e-56 190.6 0.9 5.6e-56 189.7 0.9 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain DUF371 PF04027.13 EAN33489.1 - 0.15 12.0 0.1 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF371) BRE1 PF08647.11 EAN33490.1 - 0.0031 17.6 4.1 0.0031 17.6 4.1 6.9 4 1 4 8 8 8 2 BRE1 E3 ubiquitin ligase DUF2312 PF10073.9 EAN33490.1 - 0.16 11.6 4.7 1.4 8.6 0.1 4.2 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2312) HSBP1 PF06825.12 EAN33490.1 - 6.7 6.6 10.4 8.2 6.4 0.6 4.8 5 0 0 5 5 5 0 Heat shock factor binding protein 1 MBOAT PF03062.19 EAN33491.1 - 1.1e-19 71.1 20.0 1.1e-19 71.1 20.0 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EAN33491.1 - 0.0077 16.5 1.3 0.0077 16.5 1.3 3.0 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family Thg1 PF04446.12 EAN33492.1 - 6.1e-40 136.1 0.3 1.3e-38 131.9 0.3 2.3 1 1 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EAN33492.1 - 2.5e-37 127.7 4.8 5.2e-37 126.7 4.8 1.6 1 1 0 1 1 1 1 Thg1 C terminal domain Laminin_G_3 PF13385.6 EAN33494.1 - 1.1e-12 48.4 0.1 2.9e-12 47.0 0.1 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_C62 PF12380.8 EAN33494.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase DUF1080 PF06439.11 EAN33494.1 - 0.14 12.2 0.1 0.42 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) Rgp1 PF08737.10 EAN33495.1 - 1.3e-05 24.6 0.5 0.001 18.4 0.3 2.3 2 0 0 2 2 2 2 Rgp1 Arrestin_N PF00339.29 EAN33495.1 - 0.058 13.4 1.9 0.94 9.5 0.4 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain ABC_tran PF00005.27 EAN33496.1 - 1.1e-34 119.9 0.1 2.3e-34 118.9 0.1 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EAN33496.1 - 1.5e-31 110.1 7.8 2.4e-31 109.4 7.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 EAN33496.1 - 7.8e-07 29.2 1.8 0.037 13.8 0.1 2.8 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 EAN33496.1 - 8.7e-06 24.7 0.0 0.0034 16.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EAN33496.1 - 1.2e-05 24.9 4.1 0.00019 21.0 4.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EAN33496.1 - 0.0064 17.0 0.0 0.017 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAN33496.1 - 0.0089 16.3 0.5 0.037 14.3 0.5 2.1 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EAN33496.1 - 0.0091 16.0 0.1 0.71 9.9 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EAN33496.1 - 0.018 15.0 3.0 3 7.7 0.5 3.3 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.6 EAN33496.1 - 0.033 14.4 0.0 0.081 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAN33496.1 - 0.036 13.8 0.2 0.094 12.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 EAN33496.1 - 0.039 13.7 0.0 0.45 10.2 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EAN33496.1 - 0.04 13.8 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 EAN33496.1 - 0.044 13.5 2.4 4.1 7.1 0.0 2.5 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.29 EAN33496.1 - 0.064 13.7 2.5 0.5 10.8 2.5 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EAN33496.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EAN33496.1 - 0.093 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 EAN33496.1 - 0.094 13.1 0.0 2.2 8.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 EAN33496.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EAN33496.1 - 0.12 12.1 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAN33496.1 - 0.18 12.2 0.0 0.4 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EAN33496.1 - 0.23 12.0 2.3 0.57 10.6 1.9 1.9 1 1 0 1 1 1 0 AAA domain DUF2909 PF11137.8 EAN33497.1 - 0.016 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) FAINT PF04385.15 EAN33500.1 - 3.8e-44 148.6 75.3 1.7e-07 31.2 2.0 9.4 9 0 0 9 9 9 9 Domain of unknown function, DUF529 Rdx PF10262.9 EAN33500.1 - 0.056 13.6 0.0 28 5.0 0.0 3.6 3 0 0 3 3 3 0 Rdx family FAINT PF04385.15 EAN33501.1 - 1.6e-89 294.1 146.5 1.5e-07 31.4 0.1 20.5 20 1 0 20 20 20 18 Domain of unknown function, DUF529 PsaD PF02531.16 EAN33501.1 - 0.015 14.8 0.0 0.062 12.8 0.0 2.1 1 0 0 1 1 1 0 PsaD Cupredoxin_1 PF13473.6 EAN33501.1 - 0.12 12.5 1.5 5.5 7.2 0.1 3.7 2 0 0 2 2 2 0 Cupredoxin-like domain Hepatitis_core PF00906.20 EAN33502.1 - 0.12 12.0 0.0 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Hepatitis core antigen zf-RING_11 PF17123.5 EAN33504.1 - 0.011 15.4 1.0 0.047 13.4 1.0 2.1 1 0 0 1 1 1 0 RING-like zinc finger WD40 PF00400.32 EAN33504.1 - 0.016 16.1 1.8 0.16 12.9 0.1 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-C3H2C3 PF17122.5 EAN33504.1 - 0.022 14.8 4.2 0.087 12.9 4.2 2.1 1 0 0 1 1 1 0 Zinc-finger ANAPC4_WD40 PF12894.7 EAN33504.1 - 0.11 12.8 0.0 3 8.2 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain YafO_toxin PF13957.6 EAN33504.1 - 0.17 11.9 0.4 0.46 10.5 0.4 1.7 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system zf-C3HC4_2 PF13923.6 EAN33504.1 - 0.73 9.7 8.9 0.082 12.8 3.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3276 PF11680.8 EAN33504.1 - 3.6 7.7 6.3 5.5 7.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3276) 2-oxoacid_dh PF00198.23 EAN33506.1 - 1.4e-78 263.6 0.1 1.8e-78 263.2 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EAN33506.1 - 1.6e-18 66.3 0.3 2.7e-18 65.6 0.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EAN33506.1 - 0.081 12.8 0.2 2.9 7.8 0.1 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like RnfC_N PF13375.6 EAN33506.1 - 0.14 12.2 0.1 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF5488 PF17590.2 EAN33506.1 - 0.21 11.4 1.1 1.5 8.6 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5488) GSH_synth_ATP PF03917.17 EAN33508.1 - 4.2e-55 187.0 0.0 6e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EAN33508.1 - 6.5e-20 71.5 1.7 1.1e-19 70.8 0.1 2.2 3 0 0 3 3 3 1 Eukaryotic glutathione synthase RanGAP1_C PF07834.11 EAN33508.1 - 0.0063 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 RanGAP1 C-terminal domain GSH_synth_ATP PF03917.17 EAN33509.1 - 5.7e-51 173.4 0.0 1.4e-50 172.2 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EAN33509.1 - 3.6e-14 53.1 0.0 1e-13 51.6 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic glutathione synthase LPD39 PF18858.1 EAN33509.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 DUF4964 PF16334.5 EAN33510.1 - 0.0026 17.3 0.1 0.1 12.2 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4964) Gal_Lectin PF02140.18 EAN33510.1 - 0.011 16.1 6.6 0.21 12.1 0.1 3.9 4 0 0 4 4 4 0 Galactose binding lectin domain Prefoldin_2 PF01920.20 EAN33511.1 - 2.4e-15 56.4 10.3 2.8e-15 56.2 10.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 EAN33511.1 - 0.00019 21.4 2.9 0.00045 20.2 2.9 1.7 1 1 0 1 1 1 1 Prefoldin subunit DUF4201 PF13870.6 EAN33511.1 - 0.00056 19.7 4.1 0.003 17.3 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) XhlA PF10779.9 EAN33511.1 - 0.032 14.4 3.1 0.032 14.4 3.1 2.0 2 1 0 2 2 2 0 Haemolysin XhlA Prefoldin PF02996.17 EAN33511.1 - 0.038 13.9 2.6 0.038 13.9 2.6 2.0 1 1 1 2 2 2 0 Prefoldin subunit FliD_C PF07195.12 EAN33511.1 - 0.039 13.4 4.4 0.067 12.6 4.4 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus COG5 PF10392.9 EAN33511.1 - 0.046 13.9 0.7 0.046 13.9 0.7 1.8 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF1664 PF07889.12 EAN33511.1 - 0.048 13.7 0.7 0.048 13.7 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 EAN33511.1 - 0.054 13.6 2.9 0.051 13.7 1.5 1.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Osmo_CC PF08946.10 EAN33511.1 - 0.15 12.4 4.0 0.43 10.9 0.5 2.4 2 1 0 2 2 2 0 Osmosensory transporter coiled coil PLAC9 PF15205.6 EAN33511.1 - 0.15 12.5 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Placenta-specific protein 9 Fib_alpha PF08702.10 EAN33511.1 - 0.16 12.2 7.1 0.29 11.3 7.1 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PspA_IM30 PF04012.12 EAN33511.1 - 0.19 11.3 7.8 0.12 11.9 1.2 2.0 2 0 0 2 2 2 0 PspA/IM30 family Cortex-I_coil PF09304.10 EAN33511.1 - 0.22 11.7 5.3 0.38 11.0 0.4 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil End3 PF12761.7 EAN33511.1 - 0.23 11.6 4.9 0.35 11.0 4.9 1.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF4665 PF15679.5 EAN33511.1 - 0.37 11.4 5.7 0.099 13.3 2.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Spc7 PF08317.11 EAN33511.1 - 1 8.2 10.4 3.8 6.3 10.4 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.12 EAN33511.1 - 1.1 9.7 6.1 1.1 9.8 2.6 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 EAN33511.1 - 1.2 9.4 8.6 51 4.2 8.7 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 EAN33511.1 - 1.7 9.1 5.5 0.46 10.9 1.3 2.3 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) Muted PF14942.6 EAN33511.1 - 1.8 8.9 8.5 0.89 9.9 4.8 1.8 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Atg14 PF10186.9 EAN33511.1 - 3.3 6.7 9.4 4.8 6.2 9.4 1.2 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 EAN33511.1 - 8.2 6.7 10.0 5.1 7.4 1.1 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 CENP-H PF05837.12 EAN33512.1 - 0.063 13.7 0.9 0.1 13.0 0.9 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Dus PF01207.17 EAN33513.1 - 1.6e-68 231.1 0.0 1.9e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EAN33513.1 - 2.1e-05 24.1 0.0 5.2e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 EAN33513.1 - 0.00058 19.2 0.0 0.00089 18.6 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 EAN33513.1 - 0.0007 19.0 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 EAN33513.1 - 0.0023 17.4 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase TMP-TENI PF02581.17 EAN33513.1 - 0.003 16.9 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase IMPDH PF00478.25 EAN33513.1 - 0.0095 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EAN33513.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DHO_dh PF01180.21 EAN33513.1 - 0.063 12.5 0.1 0.25 10.5 0.0 1.9 1 1 0 2 2 2 0 Dihydroorotate dehydrogenase NanE PF04131.14 EAN33513.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Hom_end PF05204.14 EAN33513.1 - 0.12 12.5 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Homing endonuclease CsgA PF17334.2 EAN33514.1 - 0.03 15.1 1.1 0.063 14.0 1.1 1.5 1 0 0 1 1 1 0 Minor curli fiber component A FAST_1 PF06743.15 EAN33515.1 - 4.5e-05 23.3 3.8 0.0024 17.8 0.1 3.9 3 0 0 3 3 3 2 FAST kinase-like protein, subdomain 1 CGI-121 PF08617.10 EAN33516.1 - 5.8e-19 68.8 0.4 7.5e-19 68.4 0.4 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 MORN PF02493.20 EAN33517.1 - 1.1e-20 72.2 37.7 0.00015 21.4 0.9 9.1 9 0 0 9 9 9 7 MORN repeat Avl9 PF09794.9 EAN33518.1 - 0.0031 16.3 0.0 0.0057 15.4 0.0 1.4 1 0 0 1 1 1 1 Transport protein Avl9 MORN PF02493.20 EAN33518.1 - 0.013 15.4 0.2 0.83 9.7 0.0 2.6 2 0 0 2 2 2 0 MORN repeat BUD22 PF09073.10 EAN33518.1 - 0.098 12.0 26.7 0.14 11.5 26.7 1.1 1 0 0 1 1 1 0 BUD22 CDC27 PF09507.10 EAN33518.1 - 1.4 8.3 30.3 2.9 7.2 30.3 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Neur_chan_memb PF02932.16 EAN33518.1 - 1.4 8.9 7.3 1.4 8.9 1.3 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Avl9 PF09794.9 EAN33519.1 - 4.1e-10 38.9 0.8 5.9e-06 25.2 0.2 2.2 2 0 0 2 2 2 2 Transport protein Avl9 TCTP PF00838.17 EAN33520.1 - 8.8e-51 172.5 2.5 9.9e-51 172.4 2.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Big_3 PF07523.12 EAN33520.1 - 0.058 13.7 0.5 0.17 12.2 0.1 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) HIT PF01230.23 EAN33520.1 - 0.085 13.6 0.0 0.14 13.0 0.0 1.4 1 0 0 1 1 1 0 HIT domain zf-MYND PF01753.18 EAN33521.1 - 1.5e-11 44.1 12.9 2.7e-11 43.4 12.9 1.4 1 0 0 1 1 1 1 MYND finger HARP PF07443.13 EAN33521.1 - 0.038 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 HepA-related protein (HARP) GTP_EFTU PF00009.27 EAN33522.1 - 4.7e-56 189.4 0.1 7.2e-56 188.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EAN33522.1 - 3.4e-38 130.1 0.1 7.1e-38 129.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EAN33522.1 - 4.3e-28 97.2 0.1 1.9e-27 95.1 0.1 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 EAN33522.1 - 5.6e-28 96.8 0.0 1.4e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EAN33522.1 - 2.9e-17 62.8 0.1 6.7e-17 61.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF2111 PF09884.9 EAN33522.1 - 0.037 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) RSV_NS2 PF03113.14 EAN33522.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 RF3_C PF16658.5 EAN33522.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EAN33522.1 - 0.09 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EAN33523.1 - 1.3e-42 144.1 0.2 2.1e-42 143.5 0.2 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EAN33523.1 - 5.7e-23 81.2 0.0 1.3e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EAN33523.1 - 1.1e-20 73.5 0.0 2.2e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EAN33523.1 - 4.2e-12 45.9 0.0 9.5e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EAN33523.1 - 3.9e-06 27.0 0.2 0.03 14.4 0.0 2.3 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 EAN33523.1 - 0.00094 18.2 0.2 0.0023 17.0 0.1 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 EAN33523.1 - 0.003 16.9 0.1 0.0041 16.5 0.1 1.2 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 EAN33523.1 - 0.031 13.8 0.5 25 4.3 0.0 3.8 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAN33523.1 - 0.063 12.7 0.1 0.14 11.6 0.1 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TFIID_30kDa PF03540.13 EAN33524.1 - 0.0081 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit DUF223 PF02721.14 EAN33524.1 - 0.04 14.2 0.1 0.059 13.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF223 SET PF00856.28 EAN33525.1 - 8.1e-13 49.1 0.1 1.2e-11 45.3 0.1 2.9 1 1 0 1 1 1 1 SET domain DUF2963 PF11178.8 EAN33525.1 - 0.055 13.2 4.8 0.28 10.9 0.4 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) HEAT PF02985.22 EAN33527.1 - 1.8e-16 58.8 0.3 0.027 14.7 0.0 7.9 8 0 0 8 8 8 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EAN33527.1 - 6.7e-14 52.3 0.7 0.015 15.9 0.0 6.5 3 1 3 6 6 6 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EAN33527.1 - 1.4e-12 47.8 0.0 0.00021 21.6 0.0 6.1 5 2 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 EAN33527.1 - 1.3e-10 41.5 0.0 0.00062 20.2 0.0 6.2 5 1 1 6 6 6 2 HEAT-like repeat Importin_rep_4 PF18808.1 EAN33527.1 - 2e-10 40.8 1.7 3.5e-08 33.6 0.0 3.9 4 0 0 4 4 4 1 Importin repeat DUF3385 PF11865.8 EAN33527.1 - 4.6e-06 26.6 7.8 0.012 15.6 0.0 5.6 6 1 0 7 7 7 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 EAN33527.1 - 0.00065 19.8 1.8 0.67 10.0 0.0 4.1 3 3 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EAN33527.1 - 0.0019 18.2 2.1 2 8.6 0.0 6.1 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EAN33527.1 - 0.0023 18.1 4.2 0.52 10.5 0.1 5.4 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 RRM_1 PF00076.22 EAN33529.1 - 7.8e-10 38.4 0.0 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAN33529.1 - 0.099 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif SMC_N PF02463.19 EAN33530.1 - 2.4e-49 167.7 0.0 5.6e-49 166.5 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EAN33530.1 - 3.9e-25 88.4 0.1 1.2e-24 86.9 0.1 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EAN33530.1 - 1.8e-11 44.4 14.0 1.1e-08 35.3 2.3 3.7 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAN33530.1 - 3.1e-07 30.0 0.0 6.5e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EAN33530.1 - 6.7e-06 26.7 27.3 6.7e-06 26.7 27.3 7.0 1 1 2 3 3 1 1 AAA domain AAA_13 PF13166.6 EAN33530.1 - 0.00093 18.0 82.2 0.022 13.4 2.6 6.3 3 2 3 7 7 7 5 AAA domain AAA_15 PF13175.6 EAN33530.1 - 0.0011 18.8 35.2 0.0011 18.8 35.2 5.1 1 1 2 4 4 1 1 AAA ATPase domain Filament PF00038.21 EAN33530.1 - 0.0013 18.4 25.1 0.0013 18.4 25.1 5.9 2 2 1 4 4 4 2 Intermediate filament protein PI3K_P85_iSH2 PF16454.5 EAN33530.1 - 0.0025 17.4 3.6 0.0025 17.4 3.6 6.6 2 2 5 7 7 7 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.11 EAN33530.1 - 0.0033 16.4 91.2 0.004 16.1 11.7 6.8 4 2 2 7 7 7 4 Spc7 kinetochore protein HrpB7 PF09486.10 EAN33530.1 - 0.067 13.6 10.6 3.7 7.9 1.1 5.0 5 1 0 5 5 5 0 Bacterial type III secretion protein (HrpB7) ABC_tran PF00005.27 EAN33530.1 - 0.068 13.7 0.0 0.068 13.7 0.0 5.7 4 3 0 4 4 2 0 ABC transporter CENP-F_leu_zip PF10473.9 EAN33530.1 - 0.07 13.1 100.1 0.33 11.0 6.4 8.5 4 2 3 8 8 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.7 EAN33530.1 - 0.12 11.9 70.1 0.091 12.3 12.9 6.4 5 2 2 7 7 6 0 Mechanosensitive ion channel porin domain APG6_N PF17675.1 EAN33530.1 - 0.27 11.7 97.3 0.54 10.8 1.8 8.2 5 3 2 7 7 7 0 Apg6 coiled-coil region FUSC PF04632.12 EAN33530.1 - 0.31 9.5 2.0 19 3.6 0.0 3.2 4 0 0 4 4 4 0 Fusaric acid resistance protein family DUF4407 PF14362.6 EAN33530.1 - 0.31 10.4 33.9 2.3 7.5 7.1 5.0 3 2 1 4 4 4 0 Domain of unknown function (DUF4407) DUF211 PF02680.14 EAN33530.1 - 0.42 10.8 5.3 17 5.6 0.0 4.6 4 1 1 5 5 5 0 Uncharacterized ArCR, COG1888 PspA_IM30 PF04012.12 EAN33530.1 - 1.4 8.4 44.8 0.57 9.7 5.5 6.7 4 1 2 7 7 7 0 PspA/IM30 family DUF1664 PF07889.12 EAN33530.1 - 4.1 7.5 55.4 3.3 7.7 5.6 8.3 4 2 6 10 10 10 0 Protein of unknown function (DUF1664) HiaBD2 PF15403.6 EAN33530.1 - 6.2 7.3 16.5 4.4 7.8 0.1 4.8 4 0 0 4 4 4 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) KfrA_N PF11740.8 EAN33530.1 - 9 7.0 6.6 15 6.3 0.9 3.4 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term Ufm1 PF03671.14 EAN33531.1 - 3e-41 139.4 0.1 3.4e-41 139.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein FAINT PF04385.15 EAN33532.1 - 4.7e-24 84.2 64.1 1.1e-06 28.5 4.3 7.7 5 3 1 7 7 7 6 Domain of unknown function, DUF529 DUF3510 PF12022.8 EAN33533.1 - 3.2e-11 43.7 1.7 8.2e-11 42.4 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3510) AAA PF00004.29 EAN33534.1 - 5.2e-41 140.2 0.0 1.1e-40 139.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EAN33534.1 - 1.1e-18 66.9 0.1 2.8e-18 65.6 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EAN33534.1 - 5.7e-11 42.1 0.1 1.3e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EAN33534.1 - 1.8e-06 28.0 0.2 1.8e-05 24.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EAN33534.1 - 2.3e-05 24.6 0.6 8.4e-05 22.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EAN33534.1 - 2.3e-05 24.9 0.2 0.0043 17.5 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EAN33534.1 - 5.4e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAN33534.1 - 0.0004 20.7 1.7 0.032 14.5 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 EAN33534.1 - 0.00061 20.0 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EAN33534.1 - 0.0018 17.7 0.1 0.02 14.2 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EAN33534.1 - 0.026 14.0 1.0 0.7 9.4 0.1 2.5 2 1 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 EAN33534.1 - 0.026 14.0 0.4 0.052 13.0 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 EAN33534.1 - 0.03 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 EAN33534.1 - 0.031 14.3 0.0 0.085 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EAN33534.1 - 0.032 14.0 1.6 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EAN33534.1 - 0.041 13.6 0.2 0.34 10.6 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 EAN33534.1 - 0.075 12.2 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.12 EAN33534.1 - 0.082 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 EAN33534.1 - 0.092 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 EAN33534.1 - 0.15 11.8 2.4 0.36 10.6 1.7 2.0 1 1 0 1 1 1 0 Septum formation initiator ATPase PF06745.13 EAN33534.1 - 0.27 10.5 3.0 0.32 10.3 0.0 2.4 3 0 0 3 3 3 0 KaiC DUF2981 PF11200.8 EAN33535.1 - 2.4e-73 247.8 2.2 2.4e-72 244.5 2.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2981) Macoilin PF09726.9 EAN33535.1 - 3 6.3 4.5 3.6 6.0 4.5 1.1 1 0 0 1 1 1 0 Macoilin family HAGH_C PF16123.5 EAN33536.1 - 3.5e-21 75.5 0.2 6.1e-21 74.7 0.2 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EAN33536.1 - 1.8e-06 28.1 0.1 0.0002 21.4 0.1 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Ribosomal_L38e PF01781.18 EAN33537.1 - 6.7e-23 80.6 1.5 7.6e-23 80.4 1.5 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family RL10P_insert PF17777.1 EAN33538.1 - 2.5e-21 75.4 0.2 5.4e-21 74.4 0.2 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EAN33538.1 - 3.5e-18 65.6 0.2 8.2e-18 64.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 EAN33538.1 - 3e-14 53.4 0.5 6.2e-14 52.4 0.5 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein UPF0242 PF06785.11 EAN33539.1 - 0.046 13.8 24.3 0.098 12.8 12.9 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus COG5 PF10392.9 EAN33539.1 - 0.075 13.2 12.7 0.13 12.4 0.6 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 ATG16 PF08614.11 EAN33539.1 - 0.19 11.9 20.0 0.68 10.1 19.7 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EAN33539.1 - 0.53 10.3 28.2 0.3 11.1 14.1 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tup_N PF08581.10 EAN33539.1 - 0.95 9.8 19.1 0.35 11.2 0.9 3.8 2 2 1 3 3 3 0 Tup N-terminal DUF1664 PF07889.12 EAN33539.1 - 0.96 9.5 11.5 2.5 8.2 2.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) GAS PF13851.6 EAN33539.1 - 1.1 8.5 26.4 0.22 10.9 3.2 3.0 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF489 PF04356.12 EAN33539.1 - 1.3 9.0 11.2 11 6.0 0.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF489) DUF148 PF02520.17 EAN33539.1 - 1.4 9.0 9.9 0.83 9.8 5.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF148 zf-C4H2 PF10146.9 EAN33539.1 - 1.4 9.2 14.2 1.2 9.4 7.5 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Myosin_tail_1 PF01576.19 EAN33539.1 - 1.5 6.5 22.7 0.83 7.4 1.1 2.3 2 1 0 2 2 2 0 Myosin tail CdvA PF18822.1 EAN33539.1 - 2.1 8.2 20.4 0.7 9.7 11.2 3.1 2 2 1 3 3 3 0 CdvA-like coiled-coil domain YabA PF06156.13 EAN33539.1 - 2.4 8.8 25.6 0.12 13.0 1.8 3.5 1 1 2 3 3 3 0 Initiation control protein YabA CC2-LZ PF16516.5 EAN33539.1 - 2.5 8.5 20.4 4.6 7.7 2.8 3.4 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator COG2 PF06148.11 EAN33539.1 - 2.8 8.0 11.8 17 5.5 6.7 3.2 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 EAN33539.1 - 4.4 6.1 23.5 1.5 7.6 14.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.11 EAN33539.1 - 6.6 5.5 20.4 39 2.9 12.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Occludin_ELL PF07303.13 EAN33539.1 - 8.1 7.2 16.4 0.14 12.9 0.9 3.5 2 1 1 3 3 3 0 Occludin homology domain TMF_TATA_bd PF12325.8 EAN33539.1 - 8.4 6.7 27.6 6.9 6.9 3.9 3.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YlqD PF11068.8 EAN33539.1 - 9 6.7 16.2 4.2 7.8 5.4 2.6 2 1 1 3 3 3 0 YlqD protein DUF1131 PF06572.12 EAN33540.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) TRAPP PF04051.16 EAN33540.1 - 2 8.1 6.3 2.7 7.7 4.3 2.3 2 1 0 2 2 2 0 Transport protein particle (TRAPP) component APG6_N PF17675.1 EAN33540.1 - 5 7.7 12.5 15 6.1 0.5 2.4 1 1 0 2 2 2 0 Apg6 coiled-coil region DUF4598 PF15370.6 EAN33541.1 - 0.038 14.5 0.1 0.11 13.0 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4598) MMR_HSR1 PF01926.23 EAN33543.1 - 3.8e-23 81.7 0.2 1.6e-21 76.5 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF1967 PF09269.11 EAN33543.1 - 5.7e-15 55.0 0.0 3.3e-14 52.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1967) FeoB_N PF02421.18 EAN33543.1 - 4.7e-10 39.2 0.1 5.1e-07 29.3 0.0 2.6 2 1 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 EAN33543.1 - 1.9e-07 31.3 0.1 3.6e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 EAN33543.1 - 0.00014 21.8 0.0 0.054 13.4 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 EAN33543.1 - 0.0066 16.2 0.1 0.55 10.0 0.1 2.6 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 EAN33543.1 - 0.012 15.6 0.2 0.054 13.5 0.1 2.1 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain cobW PF02492.19 EAN33543.1 - 0.03 13.9 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EAN33543.1 - 0.052 13.9 0.0 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EAN33543.1 - 0.11 13.0 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain GTP1_OBG PF01018.22 EAN33544.1 - 9.8e-28 96.7 4.1 1.6e-27 96.0 4.1 1.3 1 0 0 1 1 1 1 GTP1/OBG Baculo_PEP_C PF04513.12 EAN33544.1 - 0.00011 22.2 22.1 0.00023 21.2 22.1 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 EAN33544.1 - 0.0049 14.9 9.2 0.0068 14.4 9.2 1.2 1 0 0 1 1 1 1 Prominin Phasin PF05597.11 EAN33544.1 - 0.029 14.4 4.7 1.4 8.9 0.6 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Allexi_40kDa PF05549.11 EAN33544.1 - 0.048 13.2 9.1 0.085 12.4 9.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF842 PF05811.13 EAN33544.1 - 0.1 12.3 0.9 0.29 10.8 1.0 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) COG5 PF10392.9 EAN33544.1 - 0.12 12.6 4.8 0.24 11.6 4.8 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 NPV_P10 PF05531.12 EAN33544.1 - 0.14 12.6 14.5 0.78 10.2 7.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HsbA PF12296.8 EAN33544.1 - 0.2 12.1 23.8 1.5 9.3 5.2 2.8 1 1 1 2 2 2 0 Hydrophobic surface binding protein A ApoO PF09769.9 EAN33544.1 - 0.28 11.2 9.6 0.56 10.2 3.5 2.3 1 1 1 2 2 2 0 Apolipoprotein O DUF1664 PF07889.12 EAN33544.1 - 0.37 10.8 6.8 0.85 9.7 6.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AIP3 PF03915.13 EAN33544.1 - 0.38 9.8 2.9 0.59 9.2 2.9 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 FlaG PF03646.15 EAN33544.1 - 0.61 10.3 9.6 3.7 7.8 5.9 2.3 1 1 1 2 2 2 0 FlaG protein DUF2884 PF11101.8 EAN33544.1 - 0.67 9.4 5.1 1.6 8.2 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Cache_3-Cache_2 PF17201.4 EAN33544.1 - 1.2 8.3 13.4 5.2 6.3 0.8 2.1 1 1 1 2 2 2 0 Cache 3/Cache 2 fusion domain SF-assemblin PF06705.11 EAN33544.1 - 1.3 8.3 9.8 2.9 7.2 9.8 1.5 1 1 0 1 1 1 0 SF-assemblin/beta giardin Macoilin PF09726.9 EAN33544.1 - 2.3 6.7 13.0 2.6 6.5 13.0 1.1 1 0 0 1 1 1 0 Macoilin family Fib_alpha PF08702.10 EAN33544.1 - 2.3 8.4 9.0 6.4 7.0 8.6 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 EAN33544.1 - 8.5 6.7 18.2 1.4e+03 -0.4 18.2 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) U-box PF04564.15 EAN33545.1 - 1.3e-21 76.5 0.0 3.8e-21 75.0 0.0 1.8 2 0 0 2 2 2 1 U-box domain TPR_1 PF00515.28 EAN33545.1 - 9.3e-11 41.1 7.6 0.00068 19.4 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAN33545.1 - 9.3e-10 37.9 5.6 0.00059 19.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAN33545.1 - 4.5e-09 35.8 5.3 0.00043 19.9 0.2 2.7 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.6 EAN33545.1 - 2.8e-07 30.5 6.2 0.00035 20.8 0.4 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAN33545.1 - 4.9e-06 26.7 1.4 1.3e-05 25.3 1.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EAN33545.1 - 8.7e-05 23.1 0.0 0.032 14.9 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAN33545.1 - 0.00073 20.0 0.3 0.059 13.9 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAN33545.1 - 0.0014 18.7 2.9 0.19 12.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAN33545.1 - 0.0051 17.1 0.9 0.29 11.4 0.6 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAN33545.1 - 0.0067 17.0 0.2 7.2 7.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAN33545.1 - 0.0095 16.7 0.0 0.66 11.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 EAN33545.1 - 0.011 15.9 0.1 0.026 14.7 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF5113 PF17140.4 EAN33545.1 - 0.027 14.3 5.1 0.059 13.2 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5113) STb_secrete PF09075.10 EAN33545.1 - 0.23 11.5 0.4 4.6 7.4 0.0 3.0 3 0 0 3 3 3 0 Heat-stable enterotoxin B, secretory NAD_Gly3P_dh_N PF01210.23 EAN33546.1 - 7.6e-44 149.4 0.1 1.3e-43 148.7 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EAN33546.1 - 2.2e-42 144.7 0.1 4.7e-42 143.6 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 EAN33546.1 - 0.0098 15.3 0.0 0.36 10.2 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EAN33546.1 - 0.048 13.2 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pkinase PF00069.25 EAN33547.1 - 9.4e-48 162.9 0.2 2.1e-47 161.7 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN33547.1 - 1.3e-22 80.3 0.2 3.3e-22 79.0 0.2 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EAN33547.1 - 0.16 11.5 0.0 0.16 11.5 0.0 4.1 5 0 0 5 5 5 0 RIO1 family DUF1773 PF08593.10 EAN33547.1 - 3.5 8.7 7.1 9 7.4 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function Rieske_2 PF13806.6 EAN33548.1 - 0.09 12.7 0.1 0.16 11.9 0.1 1.4 1 1 0 1 1 1 0 Rieske-like [2Fe-2S] domain TRAPPC9-Trs120 PF08626.11 EAN33550.1 - 2.3e-06 25.3 0.9 4.7e-06 24.3 0.9 1.4 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ECR1_N PF14382.6 EAN33552.1 - 1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 EAN33552.1 - 4.6e-06 27.2 0.2 0.061 13.9 0.0 2.5 2 1 1 3 3 3 2 Exosome component EXOSC1/CSL4 RRM_1 PF00076.22 EAN33553.1 - 4.2e-05 23.3 0.0 0.0051 16.6 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bPH_5 PF10882.8 EAN33553.1 - 0.0089 16.1 3.2 0.33 11.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial PH domain DnaJ PF00226.31 EAN33554.1 - 4.1e-18 65.3 1.0 5.7e-18 64.8 1.0 1.2 1 0 0 1 1 1 1 DnaJ domain ELM2 PF01448.24 EAN33556.1 - 2.9e-05 24.7 1.9 7.7e-05 23.4 1.9 2.1 1 1 0 1 1 1 1 ELM2 domain DUF4744 PF15918.5 EAN33556.1 - 1.4 9.8 6.4 1.3 9.9 3.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4744) RRM_1 PF00076.22 EAN33558.1 - 7.4e-16 57.7 0.0 1.8e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 EAN33558.1 - 2.2e-11 44.2 0.9 4.7e-11 43.2 0.3 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G PRESAN PF09687.10 EAN33558.1 - 0.98 10.0 5.5 2 9.0 0.1 3.0 4 0 0 4 4 4 0 Plasmodium RESA N-terminal ubiquitin PF00240.23 EAN33559.1 - 3.6e-06 26.6 0.1 6.7e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UCH PF00443.29 EAN33560.1 - 1.7e-32 113.0 0.0 1.6e-31 109.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EAN33560.1 - 2.3e-13 49.7 0.0 7.9e-13 48.0 0.0 2.0 1 0 0 1 1 1 1 Variant UBP zinc finger UCH_1 PF13423.6 EAN33560.1 - 9.5e-09 35.3 8.1 7.2e-07 29.1 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L10 PF00466.20 EAN33561.1 - 2.3e-13 50.1 0.1 4.3e-13 49.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L10 PDZ_3 PF17815.1 EAN33562.1 - 4e-46 156.5 1.0 1.1e-45 155.1 0.2 1.9 2 0 0 2 2 2 1 PDZ domain Trypsin_2 PF13365.6 EAN33562.1 - 4.7e-12 47.0 0.0 1.3e-11 45.6 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EAN33562.1 - 4.6e-08 33.1 0.0 7.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EAN33562.1 - 3.5e-05 24.0 0.1 0.00047 20.4 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EAN33562.1 - 0.0003 20.6 0.8 0.043 13.7 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EAN33562.1 - 0.012 16.0 1.8 1.8 8.9 0.2 2.5 2 0 0 2 2 2 0 PDZ domain Trypsin PF00089.26 EAN33563.1 - 1.5e-05 25.0 0.1 3.2e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EAN33563.1 - 0.0076 17.2 1.2 0.025 15.5 0.0 2.1 2 1 0 2 2 2 1 Trypsin-like peptidase domain Glutaredoxin PF00462.24 EAN33564.1 - 1.9e-17 63.2 0.0 2.8e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 EAN33564.1 - 9.7e-05 22.8 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 EAN33564.1 - 0.00017 22.0 0.0 0.00025 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 EAN33564.1 - 0.0046 17.0 0.0 0.011 15.7 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin domain DSBA PF01323.20 EAN33564.1 - 0.0068 16.2 1.4 0.13 12.0 0.1 2.7 2 1 1 3 3 3 1 DSBA-like thioredoxin domain Redoxin PF08534.10 EAN33564.1 - 0.011 15.4 0.7 0.02 14.6 0.5 1.5 1 1 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 EAN33564.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 EAN33564.1 - 0.015 15.5 0.4 1.6 8.9 0.3 2.1 1 1 1 2 2 2 0 Thioredoxin GST_N_2 PF13409.6 EAN33564.1 - 0.015 15.5 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TraF PF13728.6 EAN33564.1 - 0.039 13.8 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein GST_N_3 PF13417.6 EAN33564.1 - 0.061 13.7 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Pim PF16765.5 EAN33565.1 - 0.3 11.3 1.1 0.78 9.9 1.1 1.6 1 0 0 1 1 1 0 Pesticin immunity protein UcrQ PF02939.16 EAN33567.1 - 0.0032 17.4 0.4 0.0048 16.8 0.4 1.3 1 0 0 1 1 1 1 UcrQ family DUF2730 PF10805.8 EAN33567.1 - 0.027 14.6 0.6 0.042 14.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Tubulin PF00091.25 EAN33568.1 - 4.4e-63 213.0 0.0 6.1e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAN33568.1 - 2.6e-42 143.9 1.8 1.1e-21 77.3 0.0 2.4 2 0 0 2 2 2 2 Tubulin C-terminal domain Dynein_attach_N PF15867.5 EAN33569.1 - 0.24 11.4 1.6 1.6 8.7 0.5 2.6 2 0 0 2 2 2 0 Dynein attachment factor N-terminus EMP24_GP25L PF01105.24 EAN33570.1 - 1.1e-25 90.6 0.5 1.7e-25 90.0 0.5 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3591 PF12157.8 EAN33571.1 - 2e-31 109.2 5.2 6.7e-18 64.6 1.1 3.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3591) Bromodomain PF00439.25 EAN33571.1 - 1.3e-14 54.0 1.2 5.3e-14 52.0 1.2 2.1 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.6 EAN33571.1 - 0.00041 20.1 0.7 0.00081 19.2 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EAN33571.1 - 0.0016 18.4 0.8 0.0031 17.5 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF573 PF04504.14 EAN33571.1 - 0.8 10.4 4.4 1.5 9.6 0.2 3.5 2 1 0 2 2 2 0 Protein of unknown function, DUF573 UPF0054 PF02130.17 EAN33572.1 - 8.3e-15 54.7 0.0 1.5e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 DUF3139 PF11337.8 EAN33572.1 - 0.11 13.2 0.6 0.26 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) MOLO1 PF17175.4 EAN33574.1 - 1.1e-25 90.1 0.2 1.9e-25 89.3 0.1 1.5 2 0 0 2 2 2 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 EAN33574.1 - 8.9e-08 32.3 0.0 5.2e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 TPM domain PIN_6 PF17146.4 EAN33575.1 - 3.2e-21 75.6 0.0 1.3e-20 73.7 0.0 2.1 2 0 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EAN33575.1 - 1.1e-20 73.6 1.3 2.6e-20 72.3 1.3 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF2321 PF10083.9 EAN33575.1 - 0.0065 16.1 0.3 0.015 15.0 0.3 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2321) TRAPP PF04051.16 EAN33576.1 - 6.9e-30 103.7 0.2 8.1e-30 103.5 0.2 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Phi-29_GP3 PF05435.11 EAN33576.1 - 0.024 14.1 0.5 0.14 11.6 0.1 2.1 2 0 0 2 2 2 0 Phi-29 DNA terminal protein GP3 DUF211 PF02680.14 EAN33576.1 - 0.12 12.5 0.3 5.4 7.2 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 zinc_ribbon_5 PF13719.6 EAN33578.1 - 0.14 12.0 0.9 0.37 10.6 0.9 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DUF883 PF05957.13 EAN33578.1 - 0.26 11.9 0.9 12 6.6 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) eIF2_C PF09173.11 EAN33579.1 - 1.1e-35 121.8 0.2 3.4e-35 120.1 0.2 1.9 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EAN33579.1 - 1e-23 83.9 0.4 1.4e-22 80.2 0.3 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EAN33579.1 - 1.3e-09 38.3 0.8 1.3e-09 38.3 0.8 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAN33579.1 - 0.00045 20.3 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAN33579.1 - 0.0058 16.6 1.5 0.083 12.8 0.1 2.5 3 0 0 3 3 3 1 RsgA GTPase FAINT PF04385.15 EAN33580.1 - 2e-117 383.4 298.3 2.9e-08 33.7 3.5 33.0 32 0 0 32 32 32 31 Domain of unknown function, DUF529 DnaB_2 PF07261.11 EAN33581.1 - 0.32 10.8 3.3 3.2 7.6 2.0 2.3 2 0 0 2 2 2 0 Replication initiation and membrane attachment TB2_DP1_HVA22 PF03134.19 EAN33582.1 - 5.1e-12 45.6 1.9 5.1e-12 45.6 1.9 2.0 2 0 0 2 2 2 1 TB2/DP1, HVA22 family BESS PF02944.20 EAN33582.1 - 0.016 15.0 0.1 0.016 15.0 0.1 1.7 2 0 0 2 2 2 0 BESS motif AMPK1_CBM PF16561.5 EAN33583.1 - 1.1e-12 48.0 0.9 2e-12 47.1 0.9 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase RRM_1 PF00076.22 EAN33584.1 - 1.3e-18 66.6 0.2 1.4e-18 66.4 0.2 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAN33584.1 - 0.00016 21.6 0.1 0.00026 20.9 0.0 1.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EAN33584.1 - 0.00073 19.1 0.0 0.00082 19.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAN33584.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif US30 PF17624.2 EAN33584.1 - 0.0018 17.4 0.0 0.0019 17.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function RRM_occluded PF16842.5 EAN33584.1 - 0.0019 18.0 0.0 0.0034 17.2 0.0 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM PF05172.13 EAN33584.1 - 0.058 13.4 0.1 0.082 12.9 0.1 1.4 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DHHC PF01529.20 EAN33585.1 - 5e-31 107.6 20.4 5e-31 107.6 20.4 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase Cons_hypoth95 PF03602.15 EAN33587.1 - 3.4e-37 127.9 0.0 4.9e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 EAN33587.1 - 7.8e-06 25.6 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 EAN33587.1 - 1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EAN33587.1 - 7.5e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAN33587.1 - 0.0008 20.1 0.0 0.0014 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAN33587.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zf-ZPR1 PF03367.13 EAN33588.1 - 8.9e-75 249.9 6.6 4.8e-37 127.3 0.2 3.4 2 1 0 2 2 2 2 ZPR1 zinc-finger domain BLOC1_2 PF10046.9 EAN33588.1 - 0.61 10.4 6.7 0.13 12.6 1.6 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-H2C2_2 PF13465.6 EAN33588.1 - 4.7 7.8 8.3 81 3.9 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-RING_4 PF14570.6 EAN33589.1 - 2.2e-20 72.1 11.3 4.2e-20 71.3 11.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EAN33589.1 - 6.4e-09 35.5 7.5 1.1e-08 34.8 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 EAN33589.1 - 1.6e-06 27.8 0.0 4.4e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.12 EAN33589.1 - 0.00019 20.9 3.0 0.00019 20.9 3.0 2.2 2 0 0 2 2 2 1 Rtf2 RING-finger zf-UDP PF14569.6 EAN33589.1 - 0.0028 17.7 4.1 0.0064 16.6 4.1 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_2 PF13639.6 EAN33589.1 - 0.0085 16.4 10.2 0.0085 16.4 10.2 1.8 2 0 0 2 2 2 1 Ring finger domain Nup35_RRM_2 PF14605.6 EAN33589.1 - 0.015 15.3 0.2 0.039 14.0 0.2 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4 PF00097.25 EAN33589.1 - 0.026 14.4 10.1 0.065 13.1 10.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAN33589.1 - 0.11 12.4 7.8 3.1 7.7 7.8 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Mucin PF01456.17 EAN33589.1 - 0.15 12.0 11.4 0.49 10.4 7.3 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-C3HC4_4 PF15227.6 EAN33589.1 - 0.47 10.6 10.3 1.3 9.2 8.9 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EAN33589.1 - 0.74 9.7 10.6 1.6 8.6 10.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SBDS_C PF09377.10 EAN33591.1 - 2.4e-30 104.9 0.2 5.9e-30 103.7 0.2 1.7 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EAN33591.1 - 2.5e-18 65.9 2.0 2.5e-18 65.9 2.0 3.2 3 1 0 3 3 3 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF4711 PF15829.5 EAN33591.1 - 0.0054 16.7 1.4 0.011 15.7 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4711) ING PF12998.7 EAN33592.1 - 7.2e-08 32.9 5.7 7.2e-08 32.9 5.7 2.3 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding RalF_SCD PF18248.1 EAN33592.1 - 0.016 15.1 0.2 0.028 14.4 0.2 1.4 1 0 0 1 1 1 0 RalF C-terminal Sec-7 capping domain DUF5090 PF17009.5 EAN33592.1 - 0.018 15.0 2.1 0.03 14.3 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) HALZ PF02183.18 EAN33592.1 - 0.13 12.5 0.4 0.13 12.5 0.4 2.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper RAP PF08373.10 EAN33593.1 - 6.4e-16 58.2 3.7 6.4e-16 58.2 3.7 3.2 2 0 0 2 2 2 1 RAP domain zf-CCCH_7 PF18586.1 EAN33593.1 - 0.59 10.5 7.8 0.27 11.6 0.9 2.9 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Ribosomal_S13 PF00416.22 EAN33595.1 - 3.5e-49 166.4 1.1 4.1e-49 166.2 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EAN33595.1 - 0.0026 16.6 0.0 0.0034 16.2 0.0 1.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_L5_C PF00673.21 EAN33596.1 - 2.2e-22 79.0 0.0 3e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EAN33596.1 - 9.5e-18 64.3 0.0 1.7e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Picorna_P3A PF06363.11 EAN33596.1 - 0.049 13.5 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Picornaviridae P3A protein ACT_5 PF13710.6 EAN33596.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 ACT domain TM231 PF10149.9 EAN33597.1 - 0.016 14.6 0.2 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 231 Actin PF00022.19 EAN33600.1 - 4.2e-59 200.2 0.0 6.2e-57 193.0 0.0 2.4 1 1 0 1 1 1 1 Actin Actino_peptide PF14408.6 EAN33600.1 - 2.7 8.2 0.0 2.7 8.2 0.0 2.6 3 0 0 3 3 3 0 Ribosomally synthesised peptide in actinomycetes Med21 PF11221.8 EAN33601.1 - 4.2e-05 23.8 4.9 5.2e-05 23.5 4.9 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex FAP206 PF12018.8 EAN33601.1 - 0.01 15.3 0.4 0.01 15.3 0.4 1.9 1 1 0 2 2 2 0 Domain of unknown function Sigma70_r1_1 PF03979.14 EAN33601.1 - 0.11 12.5 6.3 0.79 9.8 0.1 2.6 1 1 1 2 2 2 0 Sigma-70 factor, region 1.1 zf-C4H2 PF10146.9 EAN33601.1 - 0.43 10.8 2.9 0.32 11.3 1.1 1.7 1 1 1 2 2 2 0 Zinc finger-containing protein WD40 PF00400.32 EAN33602.1 - 0.0023 18.7 6.2 8 7.5 0.4 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Pkinase PF00069.25 EAN33603.1 - 4.9e-58 196.6 0.0 2.4e-37 128.8 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EAN33603.1 - 4.8e-28 98.2 0.0 1.4e-23 83.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EAN33603.1 - 0.027 13.8 0.2 0.27 10.6 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAN33603.1 - 0.43 9.8 2.5 0.81 8.9 0.0 2.5 3 0 0 3 3 3 0 Kinase-like RabGAP-TBC PF00566.18 EAN33604.1 - 7.7e-51 172.8 4.6 1.1e-50 172.2 4.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RAP PF08373.10 EAN33606.1 - 3.3e-07 30.3 0.9 3.3e-07 30.3 0.9 2.3 2 0 0 2 2 2 1 RAP domain Peptidase_C71 PF12386.8 EAN33606.1 - 0.0059 16.3 0.6 0.018 14.7 0.6 1.8 1 1 0 1 1 1 1 Pseudomurein endo-isopeptidase Pei IMPDH PF00478.25 EAN33607.1 - 3.5e-63 213.7 0.2 2.6e-62 210.9 0.2 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EAN33607.1 - 4.6e-07 29.2 1.7 1.3e-06 27.7 1.2 1.8 1 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 EAN33607.1 - 0.019 14.4 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 EAN33607.1 - 0.027 13.9 0.3 2 7.8 0.1 2.9 3 1 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.14 EAN33607.1 - 0.092 12.0 0.8 1.5 8.0 0.1 2.5 2 1 0 3 3 3 0 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 EAN33607.1 - 0.14 11.2 0.1 0.26 10.4 0.1 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase Peptidase_M24 PF00557.24 EAN33608.1 - 1.1e-28 100.3 0.1 1.5e-28 99.9 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AAA_32 PF13654.6 EAN33608.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain VASP_tetra PF08776.11 EAN33609.1 - 0.22 11.1 3.4 0.43 10.2 3.4 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain BHD_1 PF10403.9 EAN33610.1 - 2.7e-09 36.7 0.2 6.8e-09 35.4 0.2 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.9 EAN33610.1 - 0.00019 21.8 0.0 0.00058 20.2 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Methyltrn_RNA_3 PF02598.17 EAN33612.1 - 2.6e-81 273.3 0.0 3.6e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase Ribosomal_L13 PF00572.18 EAN33613.1 - 1.5e-37 128.6 0.1 2.1e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 DUF5638 PF18688.1 EAN33614.1 - 0.25 11.7 4.4 0.17 12.2 1.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5638) Unpaired PF15972.5 EAN33614.1 - 1.4 8.4 8.7 0.61 9.6 1.2 2.3 2 0 0 2 2 2 0 Unpaired protein ABC2_membrane_3 PF12698.7 EAN33614.1 - 1.7 7.7 11.4 1.5e+02 1.3 11.4 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein Mvb12 PF09452.10 EAN33614.1 - 5.8 7.4 8.2 2.3 8.7 0.3 3.5 3 1 0 3 3 3 0 ESCRT-I subunit Mvb12 Sec23_BS PF08033.12 EAN33617.1 - 8.1e-16 58.6 0.2 8.1e-16 58.6 0.2 2.5 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 EAN33617.1 - 7.3e-10 38.8 0.0 1.3e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EAN33617.1 - 5.5e-09 35.8 0.0 1.5e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EAN33617.1 - 8.2e-09 35.4 3.7 1.4e-08 34.7 2.3 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EAN33617.1 - 0.019 14.8 0.0 0.061 13.2 0.0 1.8 1 0 0 1 1 1 0 Gelsolin repeat Helicase_C PF00271.31 EAN33618.1 - 3e-17 62.9 0.1 3e-17 62.9 0.1 2.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAN33618.1 - 9.8e-16 58.0 0.0 2.2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2096 PF09869.9 EAN33618.1 - 0.022 14.8 0.2 0.022 14.8 0.2 2.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2096) LSM PF01423.22 EAN33620.1 - 6.7e-20 70.6 0.0 7.6e-20 70.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAN33620.1 - 0.00026 21.0 0.0 0.00032 20.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 EAN33620.1 - 0.074 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Hfq protein RNA_POL_M_15KD PF02150.16 EAN33620.1 - 0.12 12.2 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Methyltransf_4 PF02390.17 EAN33621.1 - 5.2e-40 136.7 0.0 6.9e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 EAN33621.1 - 0.022 14.6 0.0 0.18 11.7 0.0 2.2 1 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EAN33621.1 - 0.027 14.0 0.0 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EAN33621.1 - 0.19 12.4 0.0 0.3 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF3742 PF12553.8 EAN33622.1 - 3.5 7.8 7.3 2.9 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) FAINT PF04385.15 EAN33623.1 - 2.5e-05 24.2 1.1 4.9e-05 23.3 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function, DUF529 BBS2_Mid PF14783.6 EAN33623.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region OAD_gamma PF04277.13 EAN33624.1 - 7.5 7.2 0.0 7.5 7.2 0.0 12.2 3 1 2 5 5 5 0 Oxaloacetate decarboxylase, gamma chain dUTPase PF00692.19 EAN33625.1 - 5.1e-16 58.5 0.0 1.4e-15 57.1 0.0 1.6 1 1 0 1 1 1 1 dUTPase Lac_bphage_repr PF06543.12 EAN33625.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor Rhomboid PF01694.22 EAN33627.1 - 0.00017 21.6 7.5 0.00017 21.6 7.5 1.3 1 1 0 1 1 1 1 Rhomboid family DNA_pol_A PF00476.20 EAN33630.1 - 5.6e-85 285.7 2.7 8.9e-85 285.0 2.7 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EAN33630.1 - 1.1e-25 90.4 0.2 3e-25 89.0 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease AAA_25 PF13481.6 EAN33630.1 - 1.4e-22 80.2 0.0 2.3e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EAN33630.1 - 0.00014 21.3 0.0 0.00064 19.1 0.0 2.1 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.15 EAN33630.1 - 0.00028 20.3 1.7 0.0015 17.9 0.0 2.8 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain Toprim_2 PF13155.6 EAN33630.1 - 0.00058 20.2 0.0 0.0025 18.2 0.0 2.2 1 0 0 1 1 1 1 Toprim-like AAA_22 PF13401.6 EAN33630.1 - 0.006 16.9 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAN33630.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RNase_H_2 PF13482.6 EAN33630.1 - 0.014 15.4 0.0 0.041 13.9 0.0 1.9 1 0 0 1 1 1 0 RNase_H superfamily Toprim_4 PF13662.6 EAN33630.1 - 0.018 15.5 0.0 0.071 13.6 0.0 2.1 1 0 0 1 1 1 0 Toprim domain T2SSE PF00437.20 EAN33630.1 - 0.058 12.4 0.8 0.12 11.4 0.8 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 EAN33630.1 - 0.1 13.1 3.9 0.31 11.6 0.1 3.0 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 EAN33630.1 - 0.13 12.0 0.4 0.45 10.3 0.4 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3490 PF11995.8 EAN33630.1 - 0.15 11.9 2.3 0.47 10.3 2.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Mucin PF01456.17 EAN33630.1 - 2.1 8.4 18.5 8 6.4 18.5 1.9 1 0 0 1 1 1 0 Mucin-like glycoprotein DNA_pol_phi PF04931.13 EAN33631.1 - 3.6 5.6 20.0 6.8 4.7 20.0 1.4 1 0 0 1 1 1 0 DNA polymerase phi MIF4G PF02854.19 EAN33632.1 - 0.00025 20.8 12.9 0.00025 20.8 12.9 2.7 2 2 0 2 2 2 1 MIF4G domain ATP-synt_ab PF00006.25 EAN33633.1 - 2.6e-63 213.5 0.0 5.7e-63 212.4 0.0 1.6 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EAN33633.1 - 2.5e-18 66.3 0.0 5.3e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 EAN33633.1 - 0.019 14.2 0.2 0.042 13.0 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EAN33633.1 - 0.025 14.5 0.0 0.064 13.2 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EAN33633.1 - 0.026 14.4 0.4 0.052 13.4 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 EAN33633.1 - 0.054 12.8 0.5 0.094 12.0 0.5 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 EAN33633.1 - 0.062 13.2 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 EAN33633.1 - 0.063 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EAN33633.1 - 0.12 12.9 0.6 3.6 8.0 0.2 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EAN33633.1 - 0.14 12.5 0.2 0.37 11.1 0.2 1.7 1 0 0 1 1 1 0 AAA domain SHMT PF00464.19 EAN33634.1 - 6.7e-170 565.0 0.0 8.1e-170 564.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EAN33634.1 - 0.051 12.7 0.0 0.12 11.6 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class I and II Med26 PF08711.11 EAN33635.1 - 1.7e-11 44.0 0.3 4.9e-11 42.5 0.3 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF240 PF03086.14 EAN33635.1 - 2.4 8.1 7.1 1.1 9.2 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF240) DUF3810 PF12725.7 EAN33636.1 - 0.025 13.9 1.1 0.19 11.0 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) YL1 PF05764.13 EAN33636.1 - 0.046 13.8 6.0 0.059 13.5 6.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 EAN33636.1 - 0.16 10.2 9.1 0.17 10.1 9.1 1.2 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EAN33636.1 - 3.2 6.2 6.8 3.7 6.0 6.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ribosomal_L35p PF01632.19 EAN33637.1 - 1.8e-08 34.7 10.1 1.8e-08 34.7 10.1 1.7 1 1 1 2 2 2 1 Ribosomal protein L35 Coatomer_WDAD PF04053.14 EAN33638.1 - 1.1e-90 304.8 2.6 3e-90 303.4 0.7 2.2 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EAN33638.1 - 2.4e-26 91.5 13.0 1.9e-07 31.7 0.2 8.1 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN33638.1 - 0.024 14.9 0.0 2.2 8.6 0.0 3.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DciA PF05258.12 EAN33639.1 - 0.098 13.1 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA RNB PF00773.19 EAN33640.1 - 3.3e-111 371.8 3.7 5.5e-111 371.0 3.7 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EAN33640.1 - 4.8e-08 32.9 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EAN33640.1 - 0.00031 20.9 0.0 0.001 19.2 0.0 1.9 1 0 0 1 1 1 1 Cold shock domain SF1-HH PF16275.5 EAN33640.1 - 0.078 13.3 0.1 0.29 11.5 0.1 2.0 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain SSP160 PF06933.11 EAN33640.1 - 1.9 6.6 9.2 3.3 5.8 9.2 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3458_C PF17432.2 EAN33641.1 - 6.3e-84 282.1 0.1 8.7e-84 281.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 EAN33641.1 - 1.6e-49 168.4 0.1 2.7e-49 167.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 EAN33641.1 - 2.4e-24 85.6 0.0 5.6e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 EAN33641.1 - 8e-14 52.3 0.0 1.6e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 EAN33641.1 - 0.054 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 M61 glycyl aminopeptidase RNase_PH PF01138.21 EAN33642.1 - 4.4e-13 49.9 0.1 7.8e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 LRR_9 PF14580.6 EAN33643.1 - 1e-12 47.9 0.2 2e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EAN33643.1 - 3.1e-08 33.8 5.2 1.5e-05 25.3 0.3 3.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAN33643.1 - 1.1e-05 25.0 3.7 0.0087 15.8 2.0 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 EAN33643.1 - 0.0075 16.2 0.0 4.6 7.5 0.0 3.7 4 0 0 4 4 4 1 Leucine Rich repeat SDA1 PF05285.12 EAN33643.1 - 0.19 11.1 17.9 0.27 10.6 17.9 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EAN33643.1 - 8.3 5.6 17.3 11 5.2 17.3 1.2 1 0 0 1 1 1 0 BUD22 Wbp11 PF09429.10 EAN33644.1 - 3e-09 37.1 15.5 5.2e-09 36.4 14.5 1.9 1 1 0 1 1 1 1 WW domain binding protein 11 GvpG PF05120.12 EAN33644.1 - 0.0072 16.3 2.1 0.014 15.4 2.1 1.5 1 0 0 1 1 1 1 Gas vesicle protein G T3SchapCesA PF11439.8 EAN33644.1 - 0.2 11.8 5.0 0.39 10.9 5.0 1.4 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA Nop25 PF09805.9 EAN33644.1 - 0.28 11.6 12.9 0.48 10.9 12.9 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SLX9 PF15341.6 EAN33644.1 - 1.9 8.9 13.9 0.31 11.4 10.0 1.7 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 RA PF00788.23 EAN33645.1 - 0.063 13.9 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Mto2_bdg PF12808.7 EAN33645.1 - 0.12 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region M16C_assoc PF08367.11 EAN33646.1 - 0.0067 15.6 0.1 0.008 15.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase M16C associated p31comet PF06581.12 EAN33646.1 - 0.076 12.2 0.1 0.08 12.1 0.1 1.0 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding MFS_1 PF07690.16 EAN33647.1 - 2.8e-20 72.5 22.0 1.8e-17 63.3 18.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 EAN33647.1 - 4.2e-05 22.4 0.8 4.2e-05 22.4 0.8 3.1 2 1 2 4 4 4 2 Vacuole effluxer Atg22 like Asn_synthase PF00733.21 EAN33649.1 - 0.0011 18.8 0.6 0.093 12.4 0.1 2.3 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EAN33649.1 - 0.0019 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain HEAT PF02985.22 EAN33650.1 - 0.026 14.8 0.1 8.8 6.9 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat DASH_Dad2 PF08654.10 EAN33650.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 Ecl1 PF12855.7 EAN33650.1 - 5.7 8.1 10.6 8.5 7.5 2.4 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins HMD PF03201.16 EAN33651.1 - 0.074 13.3 0.3 0.28 11.4 0.3 2.0 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase FAINT PF04385.15 EAN33652.1 - 4.3e-24 84.4 37.1 8.3e-05 22.6 1.7 7.9 7 0 0 7 7 7 6 Domain of unknown function, DUF529 Imm27 PF15590.6 EAN33652.1 - 0.13 12.0 1.8 1.7 8.5 0.1 3.0 2 0 0 2 2 2 0 Immunity protein 27 Snapin_Pallidin PF14712.6 EAN33652.1 - 2.9 8.4 8.0 4 7.9 1.1 2.7 2 0 0 2 2 2 0 Snapin/Pallidin DUF966 PF06136.13 EAN33652.1 - 5.8 6.5 13.4 11 5.6 13.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF3970 PF13113.6 EAN33655.1 - 0.037 14.2 0.8 0.052 13.8 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3970) DUF2985 PF11204.8 EAN33656.1 - 0.12 12.5 0.2 0.21 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) Ribosomal_L6 PF00347.23 EAN33657.1 - 1.7e-22 79.9 0.9 1.2e-11 45.1 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S15 PF00312.22 EAN33658.1 - 2.5e-20 72.5 0.8 3.7e-20 71.9 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 GAIN_A PF18619.1 EAN33658.1 - 0.21 11.8 2.6 0.23 11.7 1.0 1.9 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A TPR_2 PF07719.17 EAN33661.1 - 1.2e-18 65.6 0.0 1.5e-06 27.8 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAN33661.1 - 2.9e-17 61.7 0.1 7e-07 28.8 0.2 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAN33661.1 - 2.4e-15 55.4 1.6 0.00032 20.7 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAN33661.1 - 3.6e-10 40.2 0.3 0.00088 19.7 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAN33661.1 - 4.3e-10 39.1 0.0 0.0009 18.9 0.2 2.7 1 1 1 2 2 2 2 TPR repeat Fis1_TPR_C PF14853.6 EAN33661.1 - 1.2e-07 31.7 0.0 0.0031 17.5 0.0 3.2 3 0 0 3 3 2 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EAN33661.1 - 3.8e-07 30.2 3.9 1.9e-05 24.8 0.1 3.3 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EAN33661.1 - 1.2e-06 28.7 0.0 0.15 12.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAN33661.1 - 1.1e-05 25.9 0.0 0.67 10.9 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAN33661.1 - 8.1e-05 23.2 0.0 0.054 14.2 0.0 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAN33661.1 - 8.2e-05 22.4 0.2 0.0078 16.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAN33661.1 - 9.9e-05 22.5 0.4 0.065 13.6 0.0 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAN33661.1 - 0.00011 22.4 0.1 0.026 14.8 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAN33661.1 - 0.0032 17.6 0.0 1.6 8.9 0.0 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EAN33661.1 - 0.0065 15.6 1.6 0.0065 15.6 1.6 2.8 2 1 1 3 3 3 1 NRDE-2, necessary for RNA interference TPR_10 PF13374.6 EAN33661.1 - 0.015 15.2 0.1 0.18 11.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RhoGAP-FF1 PF16512.5 EAN33661.1 - 0.018 15.7 0.7 0.14 12.9 0.0 2.8 3 0 0 3 3 2 0 p190-A and -B Rho GAPs FF domain YfiO PF13525.6 EAN33661.1 - 0.025 14.3 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein T5orf172 PF10544.9 EAN33661.1 - 0.04 14.5 0.1 0.61 10.7 0.0 2.3 2 0 0 2 2 2 0 T5orf172 domain DUF627 PF04781.12 EAN33661.1 - 0.06 13.4 0.0 3.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF627) DUF4070 PF13282.6 EAN33661.1 - 0.13 12.4 0.2 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) DnaI_N PF07319.11 EAN33664.1 - 0.017 15.8 1.3 0.049 14.3 0.7 2.1 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus RWD PF05773.22 EAN33665.1 - 4.5e-08 33.4 1.7 1.2e-07 32.0 0.1 2.8 2 0 0 2 2 2 1 RWD domain Pkinase PF00069.25 EAN33665.1 - 5.8e-07 29.1 3.4 2.9e-06 26.9 0.6 2.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN33665.1 - 0.0068 15.7 1.4 0.019 14.3 1.4 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase UQ_con PF00179.26 EAN33665.1 - 0.027 14.1 0.4 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme RNA_pol_N PF01194.17 EAN33665.1 - 0.51 10.7 2.5 0.73 10.2 0.8 2.1 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit RF-1 PF00472.20 EAN33666.1 - 4.2e-30 104.1 0.2 6.2e-30 103.5 0.2 1.2 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.18 EAN33666.1 - 1.1e-07 31.9 1.3 2.8e-07 30.6 0.3 1.9 2 0 0 2 2 2 1 PCRF domain TBP PF00352.21 EAN33668.1 - 3.8e-05 23.6 0.1 0.0029 17.5 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) UFC1 PF08694.11 EAN33669.1 - 4.9e-71 237.4 1.1 2e-70 235.4 1.1 1.7 1 1 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 EAN33669.1 - 0.014 15.0 0.0 0.033 13.8 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme RWD PF05773.22 EAN33669.1 - 0.078 13.3 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain putAbiC PF16872.5 EAN33670.1 - 9 7.1 9.9 18 6.1 2.1 3.9 3 2 0 3 3 3 0 Putative phage abortive infection protein Phage_min_cap2 PF06152.11 EAN33673.1 - 0.017 14.1 2.0 0.033 13.1 2.0 1.5 1 0 0 1 1 1 0 Phage minor capsid protein 2 HisKA_2 PF07568.12 EAN33673.1 - 0.079 13.1 1.0 0.35 11.0 0.1 2.6 2 1 0 2 2 2 0 Histidine kinase DarA_N PF18788.1 EAN33673.1 - 1.5 8.9 7.9 3.5 7.8 3.3 3.4 2 1 0 2 2 2 0 Defence against restriction A N-terminal MIF4G_like_2 PF09090.11 EAN33674.1 - 0.00015 21.3 2.7 0.00015 21.3 2.7 1.9 2 0 0 2 2 2 1 MIF4G like MA3 PF02847.17 EAN33674.1 - 0.18 11.8 2.2 0.87 9.6 0.5 2.9 3 0 0 3 3 3 0 MA3 domain LRR_9 PF14580.6 EAN33676.1 - 2.5e-57 193.2 1.2 2.8e-57 193.0 1.2 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EAN33676.1 - 2.2e-10 40.6 20.9 2.4e-06 27.8 2.2 3.8 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAN33676.1 - 8.2e-08 31.9 8.5 1.5e-07 31.0 2.4 3.3 2 1 1 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 EAN33676.1 - 1.7 8.9 12.9 6.9 7.0 0.4 4.8 6 0 0 6 6 6 0 Leucine Rich repeat Ephrin_rec_like PF07699.13 EAN33677.1 - 1.4e-32 111.2 104.3 6.4e-12 45.1 1.4 12.5 13 0 0 13 13 13 8 Putative ephrin-receptor like DUF4972 PF16342.5 EAN33677.1 - 0.036 13.8 0.5 0.092 12.4 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) He_PIG PF05345.12 EAN33677.1 - 0.49 10.6 1.7 1.1 9.5 1.7 1.5 1 0 0 1 1 1 0 Putative Ig domain Snapin_Pallidin PF14712.6 EAN33677.1 - 1 9.9 5.1 2.2 8.8 5.1 1.5 1 0 0 1 1 1 0 Snapin/Pallidin Dynactin_p22 PF07426.11 EAN33677.1 - 1.7 8.5 9.9 0.69 9.8 6.8 1.8 2 0 0 2 2 2 0 Dynactin subunit p22 Sec3-PIP2_bind PF15277.6 EAN33679.1 - 0.0016 18.5 0.2 0.0022 18.1 0.2 1.2 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Ephrin_rec_like PF07699.13 EAN33681.1 - 3.1e-23 81.3 57.0 2e-10 40.3 3.4 6.9 6 0 0 6 6 6 5 Putative ephrin-receptor like DUF4355 PF14265.6 EAN33681.1 - 0.022 15.0 2.1 0.049 13.9 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Ephrin_rec_like PF07699.13 EAN33682.1 - 1.2e-16 60.2 54.0 5.5e-06 26.0 1.7 5.6 4 1 1 5 5 5 4 Putative ephrin-receptor like Tau95 PF09734.9 EAN33683.1 - 1.9e-10 41.7 2.0 6e-09 36.8 0.1 2.5 1 1 1 2 2 2 2 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EAN33683.1 - 0.0024 18.0 0.0 0.17 12.0 0.0 2.3 1 1 1 2 2 2 2 Tau95 Triple barrel domain Mur_ligase_M PF08245.12 EAN33684.1 - 9e-06 25.8 0.0 1.7e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Dynactin PF12455.8 EAN33685.1 - 0.0096 15.2 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Dynein associated protein DUF4781 PF16013.5 EAN33685.1 - 0.051 12.4 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) KKLCAg1 PF15204.6 EAN33686.1 - 0.0022 18.0 0.9 0.075 13.1 0.1 3.0 2 0 0 2 2 2 1 Kita-kyushu lung cancer antigen 1 HEAT PF02985.22 EAN33686.1 - 0.018 15.2 0.0 1.8 9.0 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat FAS_N PF17828.1 EAN33686.1 - 1.7 8.7 7.2 0.37 10.8 1.3 3.0 3 0 0 3 3 3 0 N-terminal domain in fatty acid synthase subunit beta PRESAN PF09687.10 EAN33687.1 - 0.0087 16.6 5.8 6.6 7.3 0.2 3.2 2 1 1 3 3 3 3 Plasmodium RESA N-terminal IPPT PF01715.17 EAN33689.1 - 1.7e-59 201.4 0.0 2.3e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 EAN33689.1 - 0.00023 20.6 0.1 0.00093 18.7 0.0 2.0 3 0 0 3 3 3 1 Isopentenyl transferase AAA_33 PF13671.6 EAN33689.1 - 0.0014 18.8 0.0 0.0042 17.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EAN33689.1 - 0.0069 15.9 0.1 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Ins_P5_2-kin PF06090.12 EAN33689.1 - 0.045 13.2 0.3 0.29 10.5 0.0 2.0 1 1 0 2 2 2 0 Inositol-pentakisphosphate 2-kinase AAA_18 PF13238.6 EAN33689.1 - 0.071 13.7 0.5 11 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.22 EAN33690.1 - 1.7e-10 40.6 0.0 2.2e-08 33.8 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAST_1 PF06743.15 EAN33691.1 - 0.58 10.1 0.0 0.58 10.1 0.0 3.9 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 MutS_V PF00488.21 EAN33693.1 - 1.2e-73 247.2 0.1 2.9e-73 245.9 0.1 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EAN33693.1 - 2.7e-26 93.0 0.7 6.7e-26 91.7 0.7 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 EAN33693.1 - 3.9e-06 27.2 0.1 1.3e-05 25.5 0.1 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EAN33693.1 - 0.0022 18.3 2.9 0.0029 17.9 0.4 2.6 3 0 0 3 3 3 1 MutS family domain IV PI3K_P85_iSH2 PF16454.5 EAN33693.1 - 0.29 10.7 7.2 0.2 11.3 0.3 2.8 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AAA_23 PF13476.6 EAN33693.1 - 0.67 10.4 5.2 7.1 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Colicin_immun PF09204.10 EAN33694.1 - 0.018 15.5 0.0 0.028 14.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity GyrB_insert PF18053.1 EAN33695.1 - 2.8 7.8 7.7 0.39 10.6 1.0 2.6 2 1 1 3 3 3 0 DNA gyrase B subunit insert domain zf-DNL PF05180.12 EAN33696.1 - 3.7e-27 94.0 1.3 5.9e-27 93.4 1.3 1.3 1 0 0 1 1 1 1 DNL zinc finger HGTP_anticodon PF03129.20 EAN33697.1 - 5.4e-24 84.2 0.0 1.7e-23 82.6 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EAN33697.1 - 8.3e-07 29.1 0.1 5.5e-06 26.5 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) FlaC_arch PF05377.11 EAN33697.1 - 0.0097 16.3 0.5 0.0097 16.3 0.5 2.4 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) ABC1 PF03109.16 EAN33697.1 - 0.079 13.1 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 ABC1 family Mucin PF01456.17 EAN33697.1 - 9 6.3 13.0 0.23 11.4 3.4 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein CIAPIN1 PF05093.13 EAN33698.1 - 2.4e-27 95.4 2.6 4.5e-27 94.5 2.6 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis PMG PF05287.12 EAN33698.1 - 0.0015 18.6 1.7 0.0015 18.6 1.7 2.0 2 0 0 2 2 2 1 PMG protein FAINT PF04385.15 EAN33700.1 - 1.5e-17 63.4 49.0 9.3e-06 25.6 0.8 6.9 6 1 1 7 7 7 4 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33701.1 - 4.6e-21 74.7 57.7 1.5e-07 31.4 1.4 6.9 6 1 0 6 6 6 5 Domain of unknown function, DUF529 Bromodomain PF00439.25 EAN33702.1 - 3.6e-21 75.0 0.6 1e-20 73.6 0.6 1.8 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EAN33702.1 - 7.7e-12 45.5 0.1 1.9e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAN33702.1 - 1.5e-07 31.4 0.1 3.3e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAN33702.1 - 4.9e-07 30.1 0.7 1.1e-06 29.0 0.7 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAN33702.1 - 0.0051 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EAN33702.1 - 0.042 13.9 0.0 0.24 11.5 0.0 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EAN33702.1 - 0.15 12.2 1.0 0.38 10.9 0.3 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Dopey_N PF04118.14 EAN33703.1 - 8.6e-87 291.1 3.3 3.3e-86 289.2 3.3 2.1 1 0 0 1 1 1 1 Dopey, N-terminal Plasmod_dom_1 PF09715.10 EAN33703.1 - 0.061 13.4 1.0 1.3 9.2 0.1 3.6 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) DUF3552 PF12072.8 EAN33703.1 - 0.32 10.4 5.8 0.23 10.8 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) IFT57 PF10498.9 EAN33703.1 - 9.6 5.1 14.1 0.089 11.7 3.5 2.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 IMCp PF12314.8 EAN33704.1 - 8.4e-13 48.4 48.4 7e-11 42.3 21.0 2.6 1 1 1 2 2 2 2 Inner membrane complex protein Mus7 PF09462.10 EAN33705.1 - 0.022 13.7 0.5 0.22 10.3 0.4 2.0 2 0 0 2 2 2 0 Mus7/MMS22 family Rhomboid PF01694.22 EAN33707.1 - 1.9e-13 50.7 6.5 2.7e-13 50.2 6.5 1.2 1 0 0 1 1 1 1 Rhomboid family Thioredoxin PF00085.20 EAN33708.1 - 1.6e-19 69.8 0.0 3.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAN33708.1 - 3.1e-06 27.4 0.1 1e-05 25.8 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EAN33708.1 - 1.3e-05 25.3 0.0 3.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EAN33708.1 - 2e-05 25.0 0.0 5.9e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EAN33708.1 - 0.00052 19.5 0.0 0.00081 18.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EAN33708.1 - 0.0025 17.7 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family KaiB PF07689.12 EAN33708.1 - 0.0031 17.2 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 KaiB domain Redoxin PF08534.10 EAN33708.1 - 0.047 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Redoxin DUF836 PF05768.14 EAN33708.1 - 0.063 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) zf-RING_2 PF13639.6 EAN33709.1 - 0.0033 17.7 5.1 0.046 14.1 4.9 2.1 1 1 1 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EAN33709.1 - 0.015 15.5 4.3 0.052 13.9 4.3 1.8 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAN33709.1 - 0.016 15.2 0.4 0.021 14.9 0.4 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HMG_box_2 PF09011.10 EAN33709.1 - 0.032 14.8 0.0 0.041 14.5 0.0 1.1 1 0 0 1 1 1 0 HMG-box domain zf-C3HC4 PF00097.25 EAN33709.1 - 0.061 13.2 4.7 0.12 12.3 4.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAN33709.1 - 0.087 12.6 0.8 0.087 12.6 0.8 2.1 2 1 1 3 3 3 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EAN33709.1 - 0.29 11.3 4.0 0.34 11.1 3.3 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EAN33709.1 - 0.45 10.4 4.7 4.6 7.2 5.1 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN33709.1 - 0.46 10.6 4.0 0.79 9.8 4.0 1.6 1 1 0 1 1 1 0 RING-type zinc-finger HVSL PF09749.9 EAN33710.1 - 4.1e-25 88.6 0.2 5.1e-25 88.3 0.2 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein PITH PF06201.13 EAN33712.1 - 7e-30 104.3 0.0 8.1e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 PITH domain OTCace_N PF02729.21 EAN33713.1 - 8e-45 152.5 0.0 1.2e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EAN33713.1 - 7.8e-36 123.5 0.0 1.1e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF4046 PF13255.6 EAN33713.1 - 0.07 13.7 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4046) FHA PF00498.26 EAN33715.1 - 1.5e-13 50.9 0.2 2.1e-11 44.0 0.1 2.7 2 0 0 2 2 2 2 FHA domain RINGv PF12906.7 EAN33715.1 - 1.1e-08 35.0 2.6 1.1e-08 35.0 2.6 2.3 2 0 0 2 2 2 1 RING-variant domain Yop-YscD_cpl PF16697.5 EAN33715.1 - 0.00012 22.3 0.0 0.00085 19.6 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain HSP70 PF00012.20 EAN33716.1 - 2e-47 161.7 39.4 2.9e-40 138.1 33.9 4.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EAN33716.1 - 0.0027 16.6 0.0 0.0083 15.0 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein GCV_T PF01571.21 EAN33717.1 - 3.2e-20 72.6 0.0 6.7e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EAN33717.1 - 1.8e-07 31.0 0.0 4.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain HEPN_AbiA_CTD PF18732.1 EAN33717.1 - 0.04 13.9 0.8 0.04 13.9 0.8 2.0 2 0 0 2 2 2 0 HEPN like, Abia C-terminal domain WD40 PF00400.32 EAN33720.1 - 1.6e-24 85.7 14.7 0.00075 20.3 0.0 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN33720.1 - 1.9e-13 50.5 0.0 0.00021 21.5 0.0 5.6 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 EAN33720.1 - 9.9e-12 44.2 1.2 1.7e-11 43.4 1.2 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DUF374 PF04028.13 EAN33720.1 - 0.11 12.1 0.1 0.69 9.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF374) Chorein_N PF12624.7 EAN33721.1 - 4.4e-21 75.2 0.2 2e-20 73.1 0.2 2.3 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 EAN33721.1 - 1.2e-07 31.8 1.7 3.3e-07 30.3 0.1 2.6 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal WhiA_N PF10298.9 EAN33722.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain VPS13_C PF16909.5 EAN33723.1 - 6e-14 52.2 0.0 1.5e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Kelch_1 PF01344.25 EAN33725.1 - 5.4e-55 182.7 1.6 4.1e-10 39.1 0.0 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 EAN33725.1 - 5.5e-29 99.5 0.3 9.1e-06 25.8 0.0 6.3 3 1 3 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EAN33725.1 - 3.8e-25 87.6 0.5 4.2e-05 23.5 0.0 6.2 5 1 2 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EAN33725.1 - 7.2e-21 74.0 0.3 0.0038 17.5 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB_2 PF02214.22 EAN33725.1 - 7.1e-18 64.7 0.0 2.3e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 EAN33725.1 - 3.3e-13 49.0 1.8 0.41 10.7 0.0 6.9 7 0 0 7 7 7 4 Kelch motif Kelch_5 PF13854.6 EAN33725.1 - 3e-08 33.5 2.5 0.95 9.5 0.1 6.3 7 0 0 7 7 7 3 Kelch motif DUF501 PF04417.12 EAN33725.1 - 0.0017 18.2 0.7 0.0017 18.2 0.7 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF501) HALZ PF02183.18 EAN33725.1 - 0.17 12.1 4.7 0.68 10.2 0.8 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Atg14 PF10186.9 EAN33725.1 - 0.37 9.8 8.1 0.6 9.2 8.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 JIP_LZII PF16471.5 EAN33725.1 - 0.59 10.3 10.0 0.059 13.5 2.9 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Exonuc_VII_L PF02601.15 EAN33725.1 - 2.8 7.4 9.9 4.2 6.9 9.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 EAN33725.1 - 5.2 6.2 11.6 0.19 11.0 1.4 2.1 1 1 1 2 2 2 0 TMPIT-like protein UDPGP PF01704.18 EAN33726.1 - 1.4e-12 47.0 0.0 7.5e-12 44.6 0.0 1.8 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EAN33726.1 - 5.1e-06 26.9 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF192 PF02643.15 EAN33727.1 - 0.025 14.7 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 GSu_C4xC__C2xCH PF09698.10 EAN33727.1 - 0.11 13.3 0.1 0.23 12.2 0.1 1.4 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) AP2 PF00847.20 EAN33728.1 - 2.6e-10 40.3 0.9 2.1e-05 24.6 0.1 2.4 2 0 0 2 2 2 2 AP2 domain Endomucin PF07010.12 EAN33728.1 - 0.0073 16.3 0.7 0.0073 16.3 0.7 1.7 2 0 0 2 2 2 1 Endomucin AP2 PF00847.20 EAN33729.1 - 4.5e-05 23.6 0.0 0.0038 17.4 0.0 2.1 2 0 0 2 2 2 2 AP2 domain DUF3258 PF11646.8 EAN33731.1 - 0.045 13.9 0.2 0.13 12.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF3258 Fucose_iso_N1 PF07881.12 EAN33731.1 - 0.23 11.3 1.9 14 5.5 0.1 2.8 1 1 1 2 2 2 0 L-fucose isomerase, first N-terminal domain PEPCK_ATP PF01293.20 EAN33732.1 - 8.2e-196 651.2 0.0 9.8e-196 650.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 EAN33732.1 - 0.027 14.9 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EAN33732.1 - 0.059 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAN33732.1 - 0.12 12.1 0.3 0.29 10.9 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNB PF00773.19 EAN33733.1 - 9.2e-88 294.7 5.0 1.1e-55 189.3 0.2 2.2 1 1 1 2 2 2 2 RNB domain OB_Dis3 PF17849.1 EAN33733.1 - 9.6e-16 57.6 0.0 2e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EAN33733.1 - 1.2e-08 35.0 0.0 5.3e-07 29.7 0.0 2.7 2 0 0 2 2 2 1 Cold shock domain PIN_4 PF13638.6 EAN33733.1 - 3.5e-06 27.3 0.0 1.3e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 PIN domain Rrp44_CSD1 PF17216.3 EAN33733.1 - 0.0045 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain RRM_1 PF00076.22 EAN33734.1 - 1.7e-58 194.3 1.2 8.7e-20 70.3 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 EAN33734.1 - 1.3e-10 41.2 2.7 3.1e-10 39.9 2.7 1.7 1 0 0 1 1 1 1 WW domain RNA_bind PF08675.11 EAN33734.1 - 2.1e-10 40.4 0.0 0.0046 16.9 0.0 3.8 3 1 0 3 3 3 3 RNA binding domain RRM_5 PF13893.6 EAN33734.1 - 8.4e-10 38.3 0.4 0.0027 17.3 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAN33734.1 - 2.1e-07 30.9 0.0 0.1 12.7 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif PHM7_cyt PF14703.6 EAN33734.1 - 0.00039 20.7 1.5 4.2 7.6 0.0 4.3 3 1 1 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 EAN33734.1 - 0.0038 17.3 0.5 0.21 11.7 0.1 2.8 2 0 0 2 2 2 1 Limkain b1 Glyco_hyd_101C PF17451.2 EAN33734.1 - 0.01 16.2 0.2 0.01 16.2 0.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase 101 beta sandwich domain Nup35_RRM_2 PF14605.6 EAN33734.1 - 0.021 14.8 0.1 3.3 7.8 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EAN33734.1 - 0.024 14.5 0.0 5.5 6.9 0.0 2.8 3 0 0 3 3 3 0 Occluded RNA-recognition motif Exo_endo_phos PF03372.23 EAN33735.1 - 2.1e-12 47.1 0.0 4.2e-11 42.8 0.0 2.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2433 PF10360.9 EAN33736.1 - 0.051 13.7 1.1 0.25 11.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) DUF3450 PF11932.8 EAN33736.1 - 0.079 12.2 0.3 0.12 11.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Sec2p PF06428.11 EAN33736.1 - 0.11 12.5 1.5 0.24 11.4 0.8 1.9 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p PI_PP_I PF18363.1 EAN33736.1 - 0.56 10.4 6.3 1.1 9.5 3.1 2.6 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Myosin_head PF00063.21 EAN33737.1 - 1.4e-182 608.5 0.8 1.8e-182 608.2 0.8 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) RsgA_GTPase PF03193.16 EAN33737.1 - 0.065 13.1 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EAN33737.1 - 0.076 13.4 0.3 0.28 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EAN33737.1 - 0.14 12.4 0.1 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain CBFD_NFYB_HMF PF00808.23 EAN33738.1 - 0.0036 17.5 1.1 0.0048 17.2 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_S13_N PF08069.12 EAN33739.1 - 1.6e-26 92.1 0.5 2.8e-26 91.3 0.5 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EAN33739.1 - 3.6e-14 52.7 1.5 6.9e-14 51.8 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein S15 Flavokinase PF01687.17 EAN33740.1 - 4e-19 69.0 0.0 7.6e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Riboflavin kinase zf-Tim10_DDP PF02953.15 EAN33740.1 - 0.15 11.7 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Tim10/DDP family zinc finger HSP70 PF00012.20 EAN33741.1 - 5.3e-23 81.1 0.8 7.1e-10 37.7 0.0 3.1 2 1 1 3 3 3 3 Hsp70 protein TPR_1 PF00515.28 EAN33741.1 - 1.1e-08 34.5 7.0 8.1e-05 22.3 0.4 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAN33741.1 - 1e-06 28.4 3.6 0.00073 19.5 0.3 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAN33741.1 - 6.1e-06 26.0 1.7 0.016 15.4 0.1 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAN33741.1 - 0.00053 19.6 1.6 0.71 9.6 0.0 3.2 2 1 1 3 3 3 2 TPR repeat NARP1 PF12569.8 EAN33741.1 - 0.0023 16.9 0.7 0.0048 15.9 0.7 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 EAN33741.1 - 0.0042 17.1 0.1 1.2 9.2 0.1 2.9 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 EAN33741.1 - 0.011 16.1 0.0 0.041 14.3 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat SPO22 PF08631.10 EAN33741.1 - 0.019 14.5 0.8 1.1 8.7 0.1 2.7 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 EAN33741.1 - 0.025 15.1 0.5 0.17 12.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAN33741.1 - 0.13 13.0 0.0 9.2 7.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosom_S12_S23 PF00164.25 EAN33742.1 - 1.9e-26 91.9 0.4 3.1e-26 91.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 EMP24_GP25L PF01105.24 EAN33743.1 - 3.1e-42 144.6 1.8 3.6e-42 144.4 1.8 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.9 EAN33743.1 - 0.053 14.0 0.6 0.053 14.0 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) MCM PF00493.23 EAN33744.1 - 1.4e-80 269.6 0.1 2.1e-72 242.9 0.1 2.4 2 0 0 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 EAN33744.1 - 1.3e-21 76.8 0.0 4e-21 75.2 0.0 1.9 1 1 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EAN33744.1 - 4.4e-16 59.1 4.6 3e-15 56.4 4.6 2.4 1 1 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EAN33744.1 - 2.2e-08 33.7 0.2 0.002 17.5 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAN33744.1 - 1e-06 28.8 0.0 3.2e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EAN33744.1 - 2.6e-05 24.1 0.0 8.5e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EAN33744.1 - 6.2e-05 23.4 0.0 0.00019 21.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAN33744.1 - 0.0055 17.0 0.1 0.2 11.9 0.0 3.1 1 1 1 2 2 2 1 AAA domain YL1 PF05764.13 EAN33744.1 - 0.008 16.3 7.2 0.024 14.8 7.2 1.8 1 0 0 1 1 1 1 YL1 nuclear protein AAA_16 PF13191.6 EAN33744.1 - 0.0088 16.4 0.1 0.077 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 EAN33744.1 - 0.013 15.2 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF3987 PF13148.6 EAN33744.1 - 0.069 12.1 0.3 13 4.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) ABC_tran PF00005.27 EAN33744.1 - 0.12 12.9 2.3 0.37 11.3 0.0 3.0 3 1 0 3 3 3 0 ABC transporter AAA_lid_2 PF17863.1 EAN33744.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA lid domain ALMT PF11744.8 EAN33744.1 - 0.54 9.0 3.9 1.6 7.4 3.9 1.8 1 0 0 1 1 1 0 Aluminium activated malate transporter UQ_con PF00179.26 EAN33745.1 - 3.7e-45 153.0 0.0 4.2e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAN33745.1 - 0.011 15.5 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 EAN33745.1 - 0.022 14.6 0.1 0.041 13.7 0.1 1.5 1 1 0 1 1 1 0 UEV domain Nicastrin PF05450.15 EAN33746.1 - 0.0052 16.3 0.3 0.011 15.3 0.3 1.5 1 0 0 1 1 1 1 Nicastrin VLPT PF07122.11 EAN33747.1 - 0.0016 18.1 1.2 0.0035 17.0 1.2 1.6 1 0 0 1 1 1 1 Variable length PCR target protein (VLPT) Nbl1_Borealin_N PF10444.9 EAN33747.1 - 0.063 12.9 8.8 0.077 12.7 0.1 3.5 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal PAS_2 PF08446.11 EAN33747.1 - 0.42 11.3 3.6 3.6 8.3 2.7 2.8 1 1 1 2 2 2 0 PAS fold PIN_8 PF18476.1 EAN33747.1 - 0.46 10.3 18.1 0.18 11.6 9.4 2.1 1 1 1 2 2 2 0 PIN like domain DUF883 PF05957.13 EAN33747.1 - 0.53 10.9 3.5 6.6 7.4 0.7 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TetR_C_13 PF16925.5 EAN33747.1 - 0.67 9.9 4.6 2.4 8.1 0.2 2.7 2 2 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain KxDL PF10241.9 EAN33747.1 - 1.4 9.3 16.2 1.1 9.6 0.9 4.1 1 1 3 4 4 4 0 Uncharacterized conserved protein PHD PF00628.29 EAN33748.1 - 0.00038 20.3 0.7 0.00038 20.3 0.7 3.2 3 0 0 3 3 3 1 PHD-finger zf-RING_2 PF13639.6 EAN33748.1 - 0.1 13.0 2.9 0.5 10.7 0.6 2.8 2 0 0 2 2 2 0 Ring finger domain Ank_2 PF12796.7 EAN33751.1 - 1.2e-32 112.3 7.2 1.7e-14 54.1 1.0 3.7 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAN33751.1 - 1.9e-27 92.2 4.8 3.6e-07 30.0 0.1 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EAN33751.1 - 5.5e-27 93.8 6.4 1.3e-11 44.7 0.1 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAN33751.1 - 1.8e-23 82.3 3.7 2.8e-06 27.5 0.0 5.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAN33751.1 - 2.6e-22 78.2 8.0 1e-05 25.7 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat TPR_11 PF13414.6 EAN33751.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.28 EAN33751.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_M3 PF01432.20 EAN33752.1 - 1.6e-41 143.0 10.4 3e-41 142.2 10.4 1.3 1 0 0 1 1 1 1 Peptidase family M3 DXP_synthase_N PF13292.6 EAN33753.1 - 4.3e-64 216.4 0.1 1.1e-36 126.4 0.0 3.4 2 1 1 3 3 3 3 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 EAN33753.1 - 5e-30 104.5 0.0 1.8e-29 102.7 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EAN33753.1 - 8.7e-18 64.4 0.0 2e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 EAN33753.1 - 0.13 11.2 0.2 2.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 EAN33753.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component zf-C2HC5 PF06221.13 EAN33754.1 - 8.3e-06 25.7 7.5 1.3e-05 25.1 7.5 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type tRNA-synt_1b PF00579.25 EAN33755.1 - 7.2e-30 104.3 0.0 1.1e-29 103.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF4455 PF14643.6 EAN33755.1 - 0.0064 15.2 0.5 0.011 14.5 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) CS PF04969.16 EAN33756.1 - 3e-16 60.2 3.4 8.3e-16 58.8 3.4 1.8 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 EAN33756.1 - 1.2e-12 47.6 0.0 3.6e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. SMYLE_N PF18615.1 EAN33756.1 - 8.6 5.8 13.8 28 4.1 13.3 1.8 1 1 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain AMP-binding PF00501.28 EAN33757.1 - 1.4e-67 228.2 0.0 2e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAN33757.1 - 0.025 15.6 0.0 0.065 14.2 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain RRT14 PF17075.5 EAN33757.1 - 0.67 10.0 4.8 1.1 9.4 4.8 1.3 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 GCV_T PF01571.21 EAN33758.1 - 1.1e-06 28.2 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain RsgI_N PF12791.7 EAN33758.1 - 0.1 12.5 0.3 0.52 10.3 0.1 2.3 2 0 0 2 2 2 0 Anti-sigma factor N-terminus DER1 PF04511.15 EAN33759.1 - 0.00049 20.1 6.2 0.00059 19.8 6.2 1.1 1 0 0 1 1 1 1 Der1-like family DUF2243 PF10002.9 EAN33759.1 - 0.097 12.8 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2243) CelTOS PF18659.1 EAN33760.1 - 0.035 14.5 3.6 1.7 9.1 3.6 2.4 1 1 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites CDC37_N PF03234.14 EAN33762.1 - 0.00028 21.8 4.5 0.0009 20.2 4.6 1.9 1 1 0 1 1 1 1 Cdc37 N terminal kinase binding V-SNARE_C PF12352.8 EAN33763.1 - 3e-07 30.6 3.3 4.9e-07 29.9 1.9 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DP PF08781.10 EAN33763.1 - 0.0088 15.9 2.1 0.025 14.5 2.1 1.8 1 0 0 1 1 1 1 Transcription factor DP DUF5089 PF17002.5 EAN33763.1 - 0.027 14.4 1.2 0.027 14.4 1.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) Sec20 PF03908.13 EAN33763.1 - 0.049 13.5 0.4 0.049 13.5 0.4 2.5 3 1 0 3 3 3 0 Sec20 Sid-5 PF17204.3 EAN33763.1 - 0.052 13.7 0.6 0.094 12.9 0.6 1.4 1 0 0 1 1 1 0 Sid-5 family DASH_Duo1 PF08651.10 EAN33763.1 - 0.054 13.3 1.9 0.077 12.8 0.3 2.1 2 0 0 2 2 2 0 DASH complex subunit Duo1 KxDL PF10241.9 EAN33763.1 - 0.33 11.2 5.7 1.2 9.4 1.7 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein PRKCSH-like PF12999.7 EAN33763.1 - 1.3 8.8 5.4 1.3 8.8 1.4 2.3 2 1 1 3 3 3 0 Glucosidase II beta subunit-like Prominin PF05478.11 EAN33763.1 - 2.2 6.1 10.4 0.25 9.2 2.5 1.9 1 1 1 2 2 2 0 Prominin SIR2 PF02146.17 EAN33764.1 - 7.7e-27 94.3 0.0 1e-17 64.7 0.0 3.1 2 0 0 2 2 2 2 Sir2 family GTP_EFTU PF00009.27 EAN33766.1 - 1.7e-64 216.9 0.1 2.5e-64 216.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EAN33766.1 - 2.3e-32 111.3 0.0 9.9e-32 109.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EAN33766.1 - 2.3e-22 78.8 0.0 4.5e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EAN33766.1 - 4.8e-14 52.2 0.0 8.9e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EAN33766.1 - 2.8e-13 50.0 0.1 8.8e-13 48.5 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAN33766.1 - 0.0014 18.7 0.1 0.0028 17.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 EAN33766.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain cwf21 PF08312.12 EAN33767.1 - 1.1e-07 31.8 9.1 2e-07 31.1 9.1 1.4 1 0 0 1 1 1 1 cwf21 domain Apolipoprotein PF01442.18 EAN33770.1 - 2e-16 60.4 0.5 3e-06 27.3 0.0 4.2 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 EAN33770.1 - 6e-08 32.8 50.6 0.0011 18.9 4.0 7.2 1 1 5 7 7 7 5 Protein of unknown function (DUF1664) DHR10 PF18595.1 EAN33770.1 - 3.5e-07 30.3 2.9 3e-05 24.0 0.0 3.9 2 2 1 3 3 3 1 Designed helical repeat protein 10 domain Spc7 PF08317.11 EAN33770.1 - 1.8e-06 27.1 0.7 1.8e-06 27.1 0.7 4.2 1 1 2 4 4 3 3 Spc7 kinetochore protein Filament PF00038.21 EAN33770.1 - 7.1e-06 25.8 27.7 0.00093 18.9 0.6 3.7 1 1 2 3 3 3 3 Intermediate filament protein Prominin PF05478.11 EAN33770.1 - 2.4e-05 22.5 43.2 6e-05 21.2 14.8 3.3 1 1 2 3 3 3 2 Prominin Tropomyosin PF00261.20 EAN33770.1 - 0.00021 20.7 21.7 0.002 17.5 1.4 4.0 2 2 0 3 3 3 2 Tropomyosin ABC_tran_CTD PF16326.5 EAN33770.1 - 0.00048 20.3 0.0 1.4 9.3 0.0 4.7 2 2 3 5 5 5 1 ABC transporter C-terminal domain IFT57 PF10498.9 EAN33770.1 - 0.00054 19.0 44.7 0.014 14.4 7.0 5.7 2 1 1 4 4 4 3 Intra-flagellar transport protein 57 Tweety PF04906.13 EAN33770.1 - 0.00075 18.3 8.2 0.00075 18.3 8.2 6.8 1 1 5 7 7 7 1 Tweety DUF4164 PF13747.6 EAN33770.1 - 0.001 19.3 1.7 0.001 19.3 1.7 6.2 2 2 2 6 6 6 1 Domain of unknown function (DUF4164) WXG100 PF06013.12 EAN33770.1 - 0.0014 18.8 4.4 4.4 7.6 0.1 6.1 2 2 3 5 5 5 0 Proteins of 100 residues with WXG SesA PF17107.5 EAN33770.1 - 0.0025 18.0 11.7 0.41 10.9 0.1 5.0 1 1 3 5 5 4 1 N-terminal domain on NACHT_NTPase and P-loop NTPases COG2 PF06148.11 EAN33770.1 - 0.0051 16.9 39.4 0.26 11.4 2.0 7.5 1 1 7 8 8 8 3 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 EAN33770.1 - 0.0059 17.0 0.1 0.0059 17.0 0.1 9.5 1 1 5 6 6 5 2 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 EAN33770.1 - 0.0074 16.5 9.5 0.0074 16.5 9.5 6.3 1 1 3 5 5 4 3 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 EAN33770.1 - 0.0096 16.0 10.0 0.0096 16.0 10.0 9.2 1 1 7 9 9 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 EAN33770.1 - 0.0097 16.5 5.7 0.81 10.4 0.0 5.4 3 2 2 5 5 5 1 SlyX Tropomyosin_1 PF12718.7 EAN33770.1 - 0.011 15.9 0.2 0.011 15.9 0.2 5.2 3 1 2 5 5 3 0 Tropomyosin like Muted PF14942.6 EAN33770.1 - 0.012 16.0 50.9 0.045 14.1 2.8 6.6 2 1 4 6 6 6 0 Organelle biogenesis, Muted-like protein XhlA PF10779.9 EAN33770.1 - 0.025 14.8 0.1 0.025 14.8 0.1 9.4 6 3 5 11 11 11 0 Haemolysin XhlA Prefoldin PF02996.17 EAN33770.1 - 0.062 13.2 21.4 2.2 8.2 0.1 7.5 4 3 6 10 10 9 0 Prefoldin subunit Occludin_ELL PF07303.13 EAN33770.1 - 0.064 14.0 7.5 12 6.7 0.0 5.5 3 2 3 6 6 5 0 Occludin homology domain EzrA PF06160.12 EAN33770.1 - 0.11 10.6 53.3 0.0048 15.2 7.1 3.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF1043 PF06295.12 EAN33770.1 - 0.15 12.1 17.9 0.61 10.1 9.3 4.6 2 1 3 5 5 5 0 Protein of unknown function (DUF1043) DUF3450 PF11932.8 EAN33770.1 - 0.15 11.3 14.4 1 8.6 0.1 4.3 2 1 4 6 6 5 0 Protein of unknown function (DUF3450) TMP_2 PF06791.13 EAN33770.1 - 0.24 11.0 1.9 0.7 9.5 0.8 2.2 1 1 0 1 1 1 0 Prophage tail length tape measure protein Transcrip_act PF04949.13 EAN33770.1 - 0.25 11.2 20.4 0.17 11.8 0.1 4.7 2 2 1 4 4 3 0 Transcriptional activator TMPIT PF07851.13 EAN33770.1 - 0.26 10.5 32.4 0.056 12.7 5.4 4.6 1 1 3 5 5 5 0 TMPIT-like protein Nup54 PF13874.6 EAN33770.1 - 0.26 11.4 11.7 3.8 7.6 0.1 4.9 2 1 3 5 5 4 0 Nucleoporin complex subunit 54 YtxH PF12732.7 EAN33770.1 - 0.35 11.4 15.7 24 5.5 1.1 6.9 3 3 0 3 3 3 0 YtxH-like protein DUF3375 PF11855.8 EAN33770.1 - 0.46 9.4 1.9 4.3 6.2 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3375) Fez1 PF06818.15 EAN33770.1 - 0.54 10.7 21.4 0.56 10.6 2.2 4.3 1 1 2 3 3 2 0 Fez1 FlaC_arch PF05377.11 EAN33770.1 - 0.68 10.4 51.9 0.81 10.1 3.7 10.0 2 1 5 8 8 8 0 Flagella accessory protein C (FlaC) GARP PF16731.5 EAN33770.1 - 0.86 9.3 5.5 0.37 10.5 1.2 2.5 2 2 1 4 4 3 0 Glutamic acid/alanine-rich protein of Trypanosoma T7SS_ESX_EspC PF10824.8 EAN33770.1 - 1 9.9 5.2 40 4.8 0.0 4.0 2 1 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm MCPsignal PF00015.21 EAN33770.1 - 1.2 9.0 38.4 0.63 9.8 11.2 5.0 1 1 4 5 5 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain V-SNARE PF05008.15 EAN33770.1 - 1.3 9.5 0.0 1.3 9.5 0.0 4.6 4 2 2 6 6 4 0 Vesicle transport v-SNARE protein N-terminus DUF1515 PF07439.11 EAN33770.1 - 1.9 8.6 12.0 11 6.2 0.3 5.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1515) DUF745 PF05335.13 EAN33770.1 - 2.1 8.0 21.6 1.1 9.0 1.7 5.0 2 1 2 5 5 5 0 Protein of unknown function (DUF745) Spectrin PF00435.21 EAN33770.1 - 2.5 8.6 11.1 1.2 9.6 0.1 4.9 3 2 2 6 6 5 0 Spectrin repeat Phasin PF05597.11 EAN33770.1 - 4.1 7.4 29.3 1.5 8.8 1.1 6.5 2 1 4 6 6 6 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Vac_Fusion PF02346.16 EAN33770.1 - 5.5 6.7 12.5 2 8.1 0.2 5.0 5 2 1 7 7 4 0 Chordopoxvirus multifunctional envelope protein A27 Bax1-I PF01027.20 EAN33771.1 - 2.2e-29 102.8 29.7 2.5e-29 102.6 29.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2443 PF10398.9 EAN33771.1 - 0.0099 15.9 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2443) DpnI PF06044.12 EAN33771.1 - 0.045 13.4 0.1 0.076 12.6 0.1 1.3 1 0 0 1 1 1 0 Dam-replacing family Herpes_LMP1 PF05297.11 EAN33771.1 - 6.6 5.8 19.4 8.2 5.5 19.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Bax1-I PF01027.20 EAN33772.1 - 4e-25 88.9 36.5 4.7e-25 88.7 36.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 EAN33772.1 - 5.1 5.3 27.9 6.2 5.0 27.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3464 PF11947.8 EAN33772.1 - 7.2 6.4 7.0 0.38 10.5 0.7 1.9 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 OAF PF14941.6 EAN33773.1 - 0.011 15.2 0.4 0.022 14.2 0.4 1.4 1 0 0 1 1 1 0 Transcriptional regulator, Out at first CDC45 PF02724.14 EAN33773.1 - 0.03 12.6 2.6 0.039 12.2 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PDDEXK_6 PF04720.12 EAN33773.1 - 0.77 9.7 6.4 1.4 8.8 6.4 1.4 1 0 0 1 1 1 0 PDDEXK-like family of unknown function EspB PF05802.11 EAN33773.1 - 2 8.4 5.6 3.1 7.7 5.6 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein Glycos_transf_4 PF00953.21 EAN33774.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 4 PI3_PI4_kinase PF00454.27 EAN33775.1 - 3e-05 24.0 6.1 0.00015 21.7 1.9 3.6 2 1 1 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FAINT PF04385.15 EAN33776.1 - 7.1e-73 240.7 128.2 3.3e-09 36.7 4.8 15.7 15 0 0 15 15 15 14 Domain of unknown function, DUF529 ANAPC4_WD40 PF12894.7 EAN33776.1 - 0.00016 21.9 3.1 4.8 7.5 0.0 6.6 8 0 0 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain FAINT PF04385.15 EAN33777.1 - 6.3e-17 61.4 32.2 7.9e-08 32.3 6.0 4.7 4 0 0 4 4 4 3 Domain of unknown function, DUF529 GLE1 PF07817.13 EAN33779.1 - 4.4e-15 55.6 1.0 7.9e-15 54.8 1.0 1.4 1 0 0 1 1 1 1 GLE1-like protein DUF3540 PF12059.8 EAN33779.1 - 0.0037 17.1 0.4 0.01 15.7 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3540) Spt4 PF06093.13 EAN33780.1 - 6.9e-27 93.4 0.3 9.3e-27 92.9 0.3 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Ribosom_S12_S23 PF00164.25 EAN33780.1 - 0.031 13.9 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S12/S23 SelP_N PF04592.14 EAN33780.1 - 0.16 11.4 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HA2 PF04408.23 EAN33781.1 - 7.5e-26 90.5 0.0 1.5e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAN33781.1 - 3.6e-22 78.5 0.0 8e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAN33781.1 - 3.3e-10 40.3 1.8 6e-09 36.2 0.5 3.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAN33781.1 - 0.00031 20.6 3.3 0.013 15.2 3.3 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAN33781.1 - 0.00031 21.0 0.1 0.0071 16.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EAN33781.1 - 0.0025 17.7 0.2 0.099 12.5 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EAN33781.1 - 0.0094 15.5 0.1 0.026 14.0 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 EAN33781.1 - 0.0096 15.9 0.1 6.5 6.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 EAN33781.1 - 0.028 13.8 0.0 0.065 12.6 0.0 1.6 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 EAN33781.1 - 0.096 12.1 0.0 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 EAN33781.1 - 3.1 8.1 5.3 0.51 10.7 0.2 2.4 2 1 0 2 2 2 0 AAA domain ANAPC4_WD40 PF12894.7 EAN33782.1 - 0.0059 16.9 0.2 2 8.8 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain ASTN_2_hairpin PF18577.1 EAN33782.1 - 0.13 12.4 2.7 0.32 11.2 2.7 1.6 1 0 0 1 1 1 0 Astrotactin-2 C-terminal beta-hairpin domain WD40 PF00400.32 EAN33782.1 - 0.18 12.7 7.4 0.69 10.9 0.1 5.1 6 0 0 6 6 6 0 WD domain, G-beta repeat Choline_kinase PF01633.20 EAN33783.1 - 1.8e-37 129.0 6.4 3.3e-34 118.4 6.4 2.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAN33783.1 - 5.7e-07 29.7 0.0 7.5e-05 22.8 0.3 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 EAN33783.1 - 0.00029 20.2 1.3 0.00077 18.9 1.3 1.7 1 0 0 1 1 1 1 Ecdysteroid kinase EAV_GP5 PF15981.5 EAN33785.1 - 0.049 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Envelope glycoprotein GP 5 of equine arteritis virus DUF417 PF04224.12 EAN33786.1 - 4.2e-05 23.2 1.3 0.00017 21.2 1.3 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF417 DUF3429 PF11911.8 EAN33786.1 - 0.015 15.6 0.6 0.03 14.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) FAINT PF04385.15 EAN33787.1 - 1.3e-08 34.8 36.5 0.00047 20.2 1.0 6.6 5 1 0 5 5 5 4 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33788.1 - 0.0021 18.1 0.1 0.0021 18.1 0.1 5.9 5 1 0 5 5 5 4 Domain of unknown function, DUF529 TFIIS_C PF01096.18 EAN33789.1 - 8.5e-19 67.1 4.8 1.8e-18 66.1 4.8 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.14 EAN33789.1 - 5.2e-18 65.6 1.6 1.2e-17 64.4 1.6 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 EAN33789.1 - 1.4e-08 34.6 2.2 1.8e-08 34.3 0.4 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain HypA PF01155.19 EAN33789.1 - 0.057 13.4 0.6 0.12 12.4 0.6 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Elf1 PF05129.13 EAN33789.1 - 0.14 12.2 2.1 0.41 10.7 2.1 1.9 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Ephrin_rec_like PF07699.13 EAN33789.1 - 0.16 11.7 1.4 0.57 10.0 0.1 2.4 2 0 0 2 2 2 0 Putative ephrin-receptor like Rep_fac-A_C PF08646.10 EAN33789.1 - 0.19 11.4 7.0 0.2 11.4 3.4 2.4 2 1 0 2 2 2 0 Replication factor-A C terminal domain zinc_ribbon_4 PF13717.6 EAN33789.1 - 1.2 9.2 3.7 26 4.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF4837 PF16125.5 EAN33791.1 - 0.035 13.1 0.1 0.049 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) EMG1 PF03587.14 EAN33792.1 - 2.6e-25 89.2 1.9 3e-25 89.0 1.9 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF1394 PF07159.12 EAN33793.1 - 0.0083 15.4 1.9 0.33 10.1 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF1394) ENTH PF01417.20 EAN33794.1 - 6.9e-25 87.5 0.0 1.1e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 ENTH domain PAP1 PF08601.10 EAN33794.1 - 1.2 8.8 14.3 1.7 8.3 14.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 EAN33794.1 - 9.1 4.7 14.9 13 4.1 14.9 1.1 1 0 0 1 1 1 0 Macoilin family LAP1C PF05609.12 EAN33795.1 - 2.7 7.0 19.5 3.2 6.7 19.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ribosomal_L3 PF00297.22 EAN33796.1 - 3.8e-164 546.0 3.8 4.3e-164 545.9 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF1599 PF07659.11 EAN33797.1 - 0.038 14.5 0.1 0.14 12.6 0.1 2.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 1 DUF3391 PF11871.8 EAN33797.1 - 0.21 12.1 0.0 0.21 12.1 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3391) KilA-N PF04383.13 EAN33797.1 - 0.42 10.5 0.0 0.42 10.5 0.0 3.1 2 1 0 2 2 2 0 KilA-N domain DUF948 PF06103.11 EAN33797.1 - 0.75 10.1 4.0 4.2 7.7 0.0 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF5412 PF17428.2 EAN33799.1 - 0.034 14.0 2.7 1.2 9.0 0.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5412) Peptidase_M54 PF07998.11 EAN33800.1 - 0.048 13.6 0.2 0.079 12.9 0.2 1.3 1 1 0 1 1 1 0 Peptidase family M54 DUF2624 PF11116.8 EAN33800.1 - 0.055 14.4 1.1 1.2 10.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2624) Josephin PF02099.17 EAN33801.1 - 2.6e-11 43.9 0.2 7.7e-11 42.4 0.1 1.8 2 0 0 2 2 2 1 Josephin UBX PF00789.20 EAN33801.1 - 2.1e-05 24.6 0.6 4.3e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 UBX domain Brix PF04427.18 EAN33802.1 - 6.6e-30 104.6 2.1 8.8e-30 104.2 2.1 1.2 1 0 0 1 1 1 1 Brix domain Ebp2 PF05890.12 EAN33803.1 - 3.3e-22 79.3 16.1 4e-22 79.0 16.1 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Aida_N PF08910.10 EAN33803.1 - 0.015 15.7 2.0 0.03 14.7 2.0 1.5 1 0 0 1 1 1 0 Aida N-terminus Acyl-CoA_ox_N PF14749.6 EAN33803.1 - 0.041 14.4 4.8 0.064 13.8 0.0 2.4 2 1 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Methyltransf_11 PF08241.12 EAN33804.1 - 1.6e-14 54.3 0.1 7e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAN33804.1 - 1.6e-13 51.2 0.0 3.9e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAN33804.1 - 6.1e-10 39.1 0.0 8.1e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAN33804.1 - 2.3e-08 33.7 0.0 3.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EAN33804.1 - 5.7e-06 26.3 0.0 8.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAN33804.1 - 0.00031 21.4 0.0 0.00076 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EAN33804.1 - 0.0021 17.7 0.1 0.0039 16.8 0.1 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 EAN33804.1 - 0.0056 16.1 0.5 0.018 14.5 0.5 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 EAN33804.1 - 0.017 14.6 0.1 0.057 12.9 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.19 EAN33804.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EAN33804.1 - 0.096 12.7 0.1 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain DHHC PF01529.20 EAN33805.1 - 5.5e-10 39.5 12.8 3.1e-09 37.0 12.8 2.1 1 1 0 1 1 1 1 DHHC palmitoyltransferase zf-CCHC PF00098.23 EAN33806.1 - 1.6e-07 31.0 10.7 6.8e-06 25.9 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EAN33806.1 - 0.0059 16.3 6.7 0.13 12.1 0.2 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EAN33806.1 - 0.0061 16.4 0.3 0.0061 16.4 0.3 2.7 3 0 0 3 3 3 1 Zinc knuckle zf-CCCH PF00642.24 EAN33808.1 - 0.0073 16.2 0.9 0.0073 16.2 0.9 3.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAN33808.1 - 4.3 7.5 14.7 0.15 12.2 1.9 3.2 3 0 0 3 3 3 0 Zinc finger domain RRM_1 PF00076.22 EAN33813.1 - 1.7e-15 56.6 0.0 3.1e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 EAN33813.1 - 0.001 19.5 0.3 0.0025 18.2 0.3 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RAP PF08373.10 EAN33814.1 - 2.9e-17 62.5 6.3 3.6e-17 62.2 4.5 2.2 2 0 0 2 2 2 1 RAP domain AAA_lid_7 PF17867.1 EAN33814.1 - 0.0056 16.9 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Midasin AAA lid domain MTES_1575 PF18741.1 EAN33814.1 - 0.0062 16.7 0.7 0.0062 16.7 0.7 2.1 2 0 0 2 2 2 1 REase_MTES_1575 Init_tRNA_PT PF04179.12 EAN33814.1 - 0.028 14.7 0.1 0.06 13.6 0.1 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Proteasome PF00227.26 EAN33815.1 - 5.2e-51 172.8 0.1 7.1e-51 172.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAN33815.1 - 2.1e-12 46.5 0.0 3.7e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature LRR_2 PF07723.13 EAN33815.1 - 0.011 16.3 0.0 0.032 14.9 0.0 1.8 1 0 0 1 1 1 0 Leucine Rich Repeat PS_pyruv_trans PF04230.13 EAN33815.1 - 0.21 11.5 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase zf-CRD PF17979.1 EAN33817.1 - 0.13 12.4 2.1 0.77 9.8 0.5 2.8 2 1 1 3 3 3 0 Cysteine rich domain with multizinc binding regions Chordopox_L2 PF05803.12 EAN33817.1 - 0.65 9.9 5.0 1.6 8.6 0.8 2.6 2 0 0 2 2 2 0 Chordopoxvirus L2 protein 7tm_1 PF00001.21 EAN33818.1 - 0.014 14.7 0.0 0.03 13.7 0.0 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Syntaxin_2 PF14523.6 EAN33818.1 - 0.17 12.3 2.5 0.3 11.5 0.8 2.2 2 0 0 2 2 2 0 Syntaxin-like protein Sad1_UNC PF07738.13 EAN33819.1 - 4.1e-15 56.0 0.0 9e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal FtsH_ext PF06480.15 EAN33819.1 - 0.26 11.6 3.9 0.15 12.4 0.8 2.2 2 0 0 2 2 2 0 FtsH Extracellular Sec63 PF02889.16 EAN33820.1 - 4.2e-63 212.9 15.1 6.1e-35 120.6 5.3 3.1 2 2 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EAN33820.1 - 4.3e-48 163.4 0.0 2.5e-25 89.3 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 EAN33820.1 - 2.1e-25 89.7 0.1 1.8e-12 47.6 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAN33820.1 - 1.6e-22 80.0 0.1 2.9e-10 40.5 0.1 3.7 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EAN33820.1 - 1.2e-07 32.1 0.2 0.044 14.1 0.0 3.7 3 1 0 3 3 3 2 AAA domain T2SSE PF00437.20 EAN33820.1 - 0.0009 18.4 0.0 1.5 7.8 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 EAN33820.1 - 0.0054 17.1 0.0 1.4 9.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 EAN33820.1 - 0.015 15.2 0.1 1.6 8.6 0.0 3.1 2 0 0 2 2 2 0 Rad17 P-loop domain PhoH PF02562.16 EAN33820.1 - 0.052 13.0 0.1 14 5.0 0.0 2.6 3 0 0 3 3 3 0 PhoH-like protein AAA_16 PF13191.6 EAN33820.1 - 0.075 13.4 0.0 8.6 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 EAN33820.1 - 0.1 12.4 0.1 0.73 9.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain DUF4817 PF16087.5 EAN33821.1 - 0.12 12.2 0.0 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) CBFD_NFYB_HMF PF00808.23 EAN33822.1 - 3.8e-18 65.5 0.3 5.7e-18 65.0 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAN33822.1 - 4.4e-18 65.9 0.1 6.6e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EAN33822.1 - 0.0044 17.2 0.2 0.01 16.0 0.1 1.6 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) TetR_C_8 PF14278.6 EAN33823.1 - 0.17 12.0 6.8 4 7.6 1.7 3.0 2 1 0 2 2 2 0 Transcriptional regulator C-terminal region Pkinase PF00069.25 EAN33824.1 - 3e-31 108.7 1.0 1.8e-17 63.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAN33824.1 - 3.5e-13 49.4 0.1 2.6e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAN33824.1 - 0.00011 21.6 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like CNDH2_M PF16869.5 EAN33825.1 - 0.26 11.9 2.2 0.19 12.4 0.3 1.7 2 0 0 2 2 2 0 PF16858 Ribosomal_L7Ae PF01248.26 EAN33827.1 - 1.3e-06 28.1 0.1 1.6e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EAN33827.1 - 0.0012 18.9 0.0 0.0014 18.7 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 GpcrRhopsn4 PF10192.9 EAN33828.1 - 8.1 5.8 17.7 1.1 8.6 1.6 3.0 2 2 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain RRM_1 PF00076.22 EAN33829.1 - 1.1e-10 41.1 0.1 0.00066 19.4 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hexapep PF00132.24 EAN33830.1 - 0.022 14.5 0.6 0.069 12.9 0.6 1.9 1 1 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EAN33830.1 - 0.031 13.2 1.1 0.032 13.2 1.1 1.0 1 0 0 1 1 1 0 L-fucokinase NTP_transferase PF00483.23 EAN33831.1 - 5.5e-10 39.2 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EAN33831.1 - 0.00035 21.0 0.0 0.00058 20.2 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain FAST_1 PF06743.15 EAN33832.1 - 0.16 12.0 5.5 0.3 11.1 0.2 3.7 2 2 2 4 4 4 0 FAST kinase-like protein, subdomain 1 OGG_N PF07934.12 EAN33832.1 - 1 9.5 0.0 1 9.5 0.0 3.2 2 1 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain Glyco_transf_20 PF00982.21 EAN33833.1 - 7.9e-96 321.6 3.7 1.5e-94 317.4 3.8 2.1 1 1 1 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EAN33833.1 - 1.4e-33 115.9 0.0 3.4e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.19 EAN33833.1 - 1.2e-10 41.2 0.0 2.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain Hydrolase_3 PF08282.12 EAN33833.1 - 0.14 11.8 1.9 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ISP3_C PF18045.1 EAN33834.1 - 0.004 17.0 0.3 0.0059 16.5 0.3 1.3 1 0 0 1 1 1 1 ISP3 C-terminal DUF4930 PF16284.5 EAN33834.1 - 0.026 14.5 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4930) eIF-1a PF01176.19 EAN33835.1 - 8.4e-11 41.5 0.1 1.2e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CoxIIa PF08113.11 EAN33835.1 - 3.3 7.6 6.6 0.27 11.1 1.4 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family DUF3546 PF12066.8 EAN33836.1 - 8.9e-09 35.5 2.9 2.2e-08 34.3 1.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 EAN33836.1 - 0.00083 19.8 5.8 0.0018 18.7 5.8 1.6 1 1 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 EAN33836.1 - 0.00083 19.1 0.2 0.0023 17.7 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_4 PF13894.6 EAN33836.1 - 0.054 14.4 3.4 0.085 13.7 2.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EAN33836.1 - 0.12 12.9 1.3 0.29 11.7 1.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type COG4 PF08318.12 EAN33837.1 - 4.7e-20 71.9 7.8 1e-19 70.9 7.8 1.6 1 1 0 1 1 1 1 COG4 transport protein ThiF PF00899.21 EAN33839.1 - 3e-41 141.4 0.0 4.1e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EAN33839.1 - 0.021 14.9 0.0 0.24 11.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase E2_bind PF08825.10 EAN33839.1 - 0.026 14.6 0.2 0.05 13.7 0.2 1.4 1 0 0 1 1 1 0 E2 binding domain TrkA_N PF02254.18 EAN33839.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain FAINT PF04385.15 EAN33840.1 - 2.3e-06 27.5 7.4 0.36 10.9 0.0 4.6 4 0 0 4 4 4 3 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN33840.1 - 0.013 15.6 7.8 0.013 15.6 7.8 6.1 7 0 0 7 7 7 0 Tash protein PEST motif Tash_PEST PF07708.11 EAN33841.1 - 6.2e-05 23.0 5.4 0.00014 21.9 5.4 1.7 1 0 0 1 1 1 1 Tash protein PEST motif Autophagy_act_C PF03987.15 EAN33841.1 - 0.096 13.3 0.6 0.93 10.1 0.1 2.5 2 0 0 2 2 2 0 Autophagocytosis associated protein, active-site domain Tash_PEST PF07708.11 EAN33842.1 - 0.00019 21.4 14.4 0.00044 20.3 3.4 3.8 3 0 0 3 3 3 2 Tash protein PEST motif TFIIA PF03153.13 EAN33842.1 - 3 7.7 31.2 4.5 7.2 31.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAINT PF04385.15 EAN33843.1 - 0.0056 16.7 1.5 0.16 12.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN33843.1 - 0.017 15.2 2.5 0.017 15.2 2.5 3.6 3 0 0 3 3 3 0 Tash protein PEST motif Ig_Tie2_1 PF10430.9 EAN33843.1 - 0.12 12.8 0.1 0.41 11.1 0.0 1.9 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 FAINT PF04385.15 EAN33844.1 - 0.013 15.6 0.3 0.013 15.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function, DUF529 PTPS PF01242.19 EAN33844.1 - 0.16 12.0 1.2 0.27 11.2 1.2 1.5 1 1 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase PBP1_TM PF14812.6 EAN33844.1 - 5 7.6 13.6 2.6 8.5 6.7 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAINT PF04385.15 EAN33845.1 - 0.0061 16.6 1.4 0.0094 16.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN33845.1 - 0.018 15.2 12.9 1.2 9.3 5.1 3.8 4 0 0 4 4 4 0 Tash protein PEST motif FAINT PF04385.15 EAN33846.1 - 1e-06 28.7 3.7 2.7e-06 27.4 3.7 1.8 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN33846.1 - 5.4e-05 23.2 1.4 5.4e-05 23.2 1.4 5.7 6 0 0 6 6 6 3 Tash protein PEST motif Spore_III_AF PF09581.10 EAN33846.1 - 9.7 6.2 11.9 1.5 8.8 7.1 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Tash_PEST PF07708.11 EAN33847.1 - 0.011 15.9 4.0 0.019 15.1 4.0 1.4 1 0 0 1 1 1 0 Tash protein PEST motif POT1 PF02765.17 EAN33847.1 - 0.045 13.6 1.2 0.16 11.8 1.1 1.9 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 ExbD PF02472.16 EAN33847.1 - 2.2 8.5 8.5 3.9 7.6 8.4 1.6 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Tash_PEST PF07708.11 EAN33848.1 - 0.018 15.2 2.4 0.018 15.2 2.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif Tash_PEST PF07708.11 EAN33849.1 - 3.1e-06 27.1 16.7 0.00019 21.5 0.6 3.1 3 0 0 3 3 3 2 Tash protein PEST motif FAINT PF04385.15 EAN33849.1 - 0.013 15.5 0.1 0.013 15.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function, DUF529 POX PF07526.11 EAN33849.1 - 0.071 13.7 3.9 0.16 12.5 3.9 1.6 1 0 0 1 1 1 0 Associated with HOX Tash_PEST PF07708.11 EAN33850.1 - 7.2e-07 29.2 15.1 1.1e-05 25.4 4.8 2.5 2 0 0 2 2 2 2 Tash protein PEST motif FAINT PF04385.15 EAN33850.1 - 0.00082 19.4 3.8 0.00082 19.4 3.8 2.2 1 1 0 2 2 2 1 Domain of unknown function, DUF529 BUD22 PF09073.10 EAN33850.1 - 0.06 12.7 25.6 0.078 12.3 25.6 1.1 1 0 0 1 1 1 0 BUD22 Neur_chan_memb PF02932.16 EAN33850.1 - 8.6 6.3 8.4 14 5.6 8.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tash_PEST PF07708.11 EAN33851.1 - 0.00016 21.7 0.1 0.00016 21.7 0.1 3.9 4 0 0 4 4 4 1 Tash protein PEST motif DUF2299 PF10061.9 EAN33853.1 - 0.00012 21.8 16.8 0.28 10.9 0.6 3.8 3 1 0 3 3 3 3 Uncharacterized conserved protein (DUF2299) IL4 PF00727.18 EAN33853.1 - 0.0032 17.7 12.8 2.7 8.3 0.4 3.5 3 0 0 3 3 3 3 Interleukin 4 Nipped-B_C PF12830.7 EAN33853.1 - 0.04 13.9 9.5 5.6 6.8 0.2 3.2 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus DUF3038 PF11237.8 EAN33853.1 - 0.58 10.2 8.9 26 4.8 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3038) Wbp11 PF09429.10 EAN33853.1 - 0.96 9.9 39.2 0.55 10.7 3.8 4.6 4 1 0 4 4 4 0 WW domain binding protein 11 SMODS PF18144.1 EAN33853.1 - 2.2 8.4 26.4 7.6 6.7 1.1 5.4 2 1 4 6 6 6 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Ku_C PF03730.14 EAN33853.1 - 2.5 8.8 44.7 2.8 8.7 6.9 4.6 4 0 0 4 4 4 0 Ku70/Ku80 C-terminal arm AnfG_VnfG PF03139.15 EAN33853.1 - 4 7.6 13.5 24 5.1 0.3 4.0 4 0 0 4 4 4 0 Vanadium/alternative nitrogenase delta subunit Plasmid_stab_B PF10784.9 EAN33853.1 - 4.2 7.3 5.2 1.1e+02 2.8 0.1 3.3 3 0 0 3 3 3 0 Plasmid stability protein Tash_PEST PF07708.11 EAN33854.1 - 5.3e-08 32.8 28.9 0.00022 21.3 0.9 4.3 4 0 0 4 4 4 3 Tash protein PEST motif PsbU PF06514.11 EAN33854.1 - 0.0026 17.7 0.0 0.0094 15.9 0.0 1.9 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) FAINT PF04385.15 EAN33855.1 - 1.5e-07 31.4 2.0 1.9e-07 31.0 0.3 2.1 1 1 1 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33856.1 - 0.0019 18.2 0.3 0.006 16.6 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN33856.1 - 0.13 12.5 0.1 0.13 12.5 0.1 3.0 2 1 0 2 2 2 0 Tash protein PEST motif FAINT PF04385.15 EAN33857.1 - 0.00021 21.3 0.2 0.00021 21.3 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN33858.1 - 7.9e-11 41.9 16.9 0.011 15.8 0.1 5.1 4 0 0 4 4 4 4 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN33858.1 - 0.0056 16.8 14.3 0.01 15.9 5.9 3.6 2 0 0 2 2 2 1 Tash protein PEST motif CODH_A_N PF18537.1 EAN33858.1 - 0.07 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain FAINT PF04385.15 EAN33859.1 - 4.7e-14 52.2 24.3 3.6e-06 27.0 0.5 5.7 5 2 0 5 5 5 4 Domain of unknown function, DUF529 bZIP_C PF12498.8 EAN33859.1 - 2.7 9.0 9.2 0.4 11.7 0.9 2.5 2 0 0 2 2 2 0 Basic leucine-zipper C terminal ANAPC4_WD40 PF12894.7 EAN33860.1 - 0.017 15.4 0.1 0.23 11.8 0.0 2.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAN33860.1 - 0.046 14.6 0.0 7 7.7 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Wtap PF17098.5 EAN33862.1 - 1e-18 67.8 10.5 1.8e-18 66.9 10.5 1.4 1 0 0 1 1 1 1 WTAP/Mum2p family TSC22 PF01166.18 EAN33862.1 - 0.047 14.0 10.3 0.06 13.7 1.0 3.8 3 0 0 3 3 3 0 TSC-22/dip/bun family Herpes_BLRF2 PF05812.12 EAN33862.1 - 0.056 13.6 0.2 0.056 13.6 0.2 3.8 2 1 2 4 4 4 0 Herpesvirus BLRF2 protein UPF0449 PF15136.6 EAN33863.1 - 0.12 12.8 3.0 0.14 12.6 3.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Ribosomal_S17e PF00833.18 EAN33865.1 - 0.04 13.8 0.1 4.9 7.1 0.0 2.3 1 1 1 2 2 2 0 Ribosomal S17 MIF4G PF02854.19 EAN33866.1 - 1.6e-17 63.9 5.3 7.1e-11 42.1 4.9 2.4 2 0 0 2 2 2 2 MIF4G domain DAG_kinase_N PF14513.6 EAN33866.1 - 2.3 8.4 5.8 1.4 9.1 0.5 2.5 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus TBP PF00352.21 EAN33868.1 - 1.5e-54 181.9 0.9 3.6e-27 94.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) KaiB PF07689.12 EAN33869.1 - 0.15 11.8 0.1 0.39 10.5 0.1 1.6 1 0 0 1 1 1 0 KaiB domain zf-C2H2_4 PF13894.6 EAN33870.1 - 9.7e-06 26.0 3.4 0.0035 18.0 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAN33870.1 - 0.0013 19.0 5.8 0.54 10.6 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EAN33870.1 - 0.0023 18.2 2.9 0.06 13.7 0.4 2.5 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 EAN33870.1 - 0.0025 18.2 3.0 0.04 14.4 0.1 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type CpXC PF14353.6 EAN33870.1 - 0.021 14.9 0.7 0.54 10.3 0.2 2.3 1 1 1 2 2 2 0 CpXC protein zf-C2H2_6 PF13912.6 EAN33870.1 - 0.023 14.7 0.7 0.28 11.2 0.3 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger zf-4CXXC_R1 PF10497.9 EAN33870.1 - 0.058 13.6 0.5 0.13 12.5 0.5 1.6 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Secretin PF00263.21 EAN33870.1 - 0.085 12.5 5.9 0.16 11.6 5.9 1.4 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein zf-met PF12874.7 EAN33870.1 - 0.11 12.9 0.8 21 5.7 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ADK PF00406.22 EAN33871.1 - 4.3e-54 182.7 0.0 5.5e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAN33871.1 - 4.7e-22 78.9 0.0 9.5e-22 77.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EAN33871.1 - 3.5e-16 58.9 0.0 8.3e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 EAN33871.1 - 0.00014 22.0 0.0 0.00027 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 EAN33871.1 - 0.00032 21.1 0.0 0.72 10.1 0.0 2.2 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 EAN33871.1 - 0.035 14.6 0.2 0.34 11.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain TP_methylase PF00590.20 EAN33872.1 - 2.5e-21 76.6 0.0 3.8e-21 76.0 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases UPF0020 PF01170.18 EAN33873.1 - 1.3e-10 41.3 0.0 7.9e-09 35.5 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EAN33873.1 - 0.0012 18.6 2.5 1.1 8.9 0.1 2.9 3 1 0 3 3 3 2 DNA methylase N6_Mtase PF02384.16 EAN33873.1 - 0.0024 17.2 0.1 0.0074 15.6 0.1 1.7 1 1 0 1 1 1 1 N-6 DNA Methylase AviRa PF11599.8 EAN33873.1 - 0.043 13.3 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 RRNA methyltransferase AviRa CDC73_N PF16050.5 EAN33873.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal DUF1764 PF08576.10 EAN33874.1 - 6.8e-08 33.3 7.2 1.1e-07 32.7 7.2 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) RRM_1 PF00076.22 EAN33874.1 - 0.028 14.2 0.2 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EFP PF01132.20 EAN33876.1 - 1.4e-05 25.0 0.2 1.9e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Ras PF00071.22 EAN33877.1 - 2.4e-41 141.1 0.5 6.8e-41 139.6 0.5 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EAN33877.1 - 3.7e-31 107.8 0.0 5.7e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAN33877.1 - 2.4e-11 43.4 0.1 1.8e-10 40.6 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAN33877.1 - 0.0058 16.7 0.0 0.011 15.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FAINT PF04385.15 EAN33878.1 - 1.1e-89 294.5 113.7 7.9e-08 32.3 5.4 15.8 15 0 0 15 15 15 15 Domain of unknown function, DUF529 OB_NTP_bind PF07717.16 EAN33879.1 - 7.7e-21 74.2 0.3 1.9e-20 73.0 0.3 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EAN33879.1 - 8.5e-17 61.4 0.0 3.6e-16 59.4 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EAN33879.1 - 1.5e-13 51.1 0.5 5.3e-13 49.3 0.0 2.3 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAN33879.1 - 5e-06 26.4 0.3 1.7e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAN33879.1 - 6.3e-06 26.5 0.2 0.00023 21.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EAN33879.1 - 0.00038 19.6 0.1 0.00068 18.8 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EAN33879.1 - 0.0016 18.8 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EAN33879.1 - 0.0022 17.5 0.1 0.006 16.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 EAN33879.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAN33879.1 - 0.13 12.4 0.1 1 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 EAN33879.1 - 0.13 12.1 0.2 2.3 8.1 0.0 2.8 3 0 0 3 3 3 0 Helicase ResIII PF04851.15 EAN33879.1 - 0.3 11.1 4.0 8.6 6.3 0.3 3.3 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit DIM1 PF02966.16 EAN33880.1 - 2.1e-66 221.7 0.3 2.4e-66 221.5 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EAN33880.1 - 0.056 13.4 0.1 0.076 13.0 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin FAM76 PF16046.5 EAN33881.1 - 1.8e-16 60.4 40.6 2.5e-16 59.9 40.6 1.3 1 0 0 1 1 1 1 FAM76 protein HU-CCDC81_euk_1 PF14908.6 EAN33883.1 - 0.085 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 ABC_tran PF00005.27 EAN33884.1 - 2.5e-19 70.1 0.0 4.5e-19 69.3 0.0 1.4 1 1 0 1 1 1 1 ABC transporter MeaB PF03308.16 EAN33884.1 - 0.00029 19.9 0.2 0.00045 19.3 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EAN33884.1 - 0.0054 16.6 0.1 0.0099 15.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase VraX PF17412.2 EAN33884.1 - 0.0063 16.1 0.2 0.12 12.0 0.0 2.9 3 0 0 3 3 3 1 Family of unknown function Zeta_toxin PF06414.12 EAN33884.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 EAN33884.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EAN33884.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EAN33884.1 - 0.028 14.7 0.0 0.086 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EAN33884.1 - 0.029 13.6 0.1 0.079 12.1 0.1 1.7 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.17 EAN33884.1 - 0.032 14.3 0.3 0.064 13.4 0.3 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 EAN33884.1 - 0.039 14.3 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EAN33884.1 - 0.04 13.9 0.1 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 EAN33884.1 - 0.043 14.3 0.6 0.08 13.4 0.6 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EAN33884.1 - 0.058 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MobB PF03205.14 EAN33884.1 - 0.1 12.5 0.4 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 EAN33884.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EAN33884.1 - 0.12 12.2 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EAN33884.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CoaE PF01121.20 EAN33884.1 - 0.15 11.7 0.0 5 6.8 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase cobW PF02492.19 EAN33884.1 - 0.16 11.5 0.1 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 EAN33884.1 - 0.2 10.5 0.5 0.3 9.9 0.5 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FAINT PF04385.15 EAN33885.1 - 5.4e-62 205.8 149.8 1.3e-08 34.8 4.5 16.5 16 0 0 16 16 16 14 Domain of unknown function, DUF529 Chordopox_A13L PF05961.11 EAN33886.1 - 0.14 12.4 0.1 0.49 10.7 0.1 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein CDC50 PF03381.15 EAN33887.1 - 4.9e-23 82.0 4.8 6.7e-23 81.6 4.8 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family AMA-1 PF02430.15 EAN33888.1 - 1e-178 595.2 16.4 4.2e-178 593.1 16.4 1.8 1 1 0 1 1 1 1 Apical membrane antigen 1 Sigma_reg_N PF13800.6 EAN33888.1 - 0.092 13.0 0.1 0.28 11.5 0.1 1.9 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Spore_YpjB PF09577.10 EAN33888.1 - 0.12 12.1 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) ETRAMP PF09716.10 EAN33888.1 - 1.5 8.9 7.1 0.45 10.6 0.1 3.2 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) RNA_pol_Rpc34 PF05158.12 EAN33890.1 - 8.4e-34 117.4 8.2 5.9e-28 98.2 0.3 2.9 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit IclR PF01614.18 EAN33890.1 - 0.21 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial transcriptional regulator Ribosomal_S25 PF03297.15 EAN33891.1 - 1.3e-38 131.3 3.5 1.4e-38 131.1 3.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Fe_dep_repress PF01325.19 EAN33891.1 - 0.031 14.5 0.2 0.049 13.8 0.2 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 EAN33891.1 - 0.05 13.5 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 EAN33891.1 - 0.1 12.2 0.4 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GntR PF00392.21 EAN33891.1 - 0.12 12.0 0.4 0.25 11.0 0.4 1.6 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family zf-RING_2 PF13639.6 EAN33893.1 - 8.7e-09 35.6 7.9 8.7e-09 35.6 7.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAN33893.1 - 2.2e-08 33.8 6.5 4.9e-08 32.7 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAN33893.1 - 1e-07 31.7 7.4 2.6e-07 30.4 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAN33893.1 - 2.9e-06 27.5 11.5 1.6e-05 25.1 11.5 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EAN33893.1 - 0.00012 21.7 2.8 0.00033 20.3 2.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EAN33893.1 - 0.00023 21.1 7.1 0.00053 19.9 7.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EAN33893.1 - 0.00036 20.0 0.8 0.00063 19.2 0.8 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 EAN33893.1 - 0.00065 19.5 7.0 0.00065 19.5 7.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EAN33893.1 - 0.00068 19.2 5.3 0.0016 18.0 5.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type ETRAMP PF09716.10 EAN33893.1 - 0.0014 18.6 0.0 0.051 13.7 0.0 2.9 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Prok-RING_4 PF14447.6 EAN33893.1 - 0.0037 17.1 8.4 0.0057 16.5 6.6 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EAN33893.1 - 0.023 14.7 9.4 0.05 13.6 7.9 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 EAN33893.1 - 0.028 14.5 4.2 0.09 12.8 4.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EAN33893.1 - 0.034 14.3 4.5 0.099 12.8 4.3 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 EAN33893.1 - 0.32 11.3 9.3 0.39 11.1 7.3 2.1 2 0 0 2 2 2 0 RING-like domain adh_short PF00106.25 EAN33895.1 - 4.8e-30 104.5 0.0 4.6e-22 78.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAN33895.1 - 1.2e-15 57.7 0.0 2.7e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EAN33895.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Dynamin_N PF00350.23 EAN33896.1 - 1.1e-11 45.1 1.7 1.9e-10 41.0 0.1 2.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EAN33896.1 - 0.006 16.7 0.0 0.035 14.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GDPD PF03009.17 EAN33897.1 - 2.4e-17 63.5 0.0 2.3e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Radical_SAM PF04055.21 EAN33897.1 - 0.0086 16.5 0.0 0.74 10.2 0.0 2.8 4 0 0 4 4 4 1 Radical SAM superfamily Adap_comp_sub PF00928.21 EAN33898.1 - 1.9e-50 171.7 1.4 2.2e-50 171.5 1.4 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EAN33898.1 - 0.14 12.1 0.5 0.3 11.0 0.5 1.6 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Methyltransf_15 PF09445.10 EAN33899.1 - 6.6e-27 94.1 0.6 1.5e-26 92.9 0.6 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RNA_GG_bind PF10258.9 EAN33899.1 - 0.0033 17.4 0.1 0.01 15.9 0.1 1.9 1 0 0 1 1 1 1 PHAX RNA-binding domain DUF1690 PF07956.11 EAN33899.1 - 0.1 13.0 5.5 0.28 11.6 5.5 1.7 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Ribosomal_S18 PF01084.20 EAN33901.1 - 8.2e-16 58.0 0.2 2.1e-15 56.6 0.2 1.8 1 0 0 1 1 1 1 Ribosomal protein S18 PDEase_I PF00233.19 EAN33902.1 - 1.5e-55 188.5 1.0 1.5e-55 188.5 1.0 1.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Phage_tail_T PF06223.12 EAN33902.1 - 0.14 12.7 0.0 3.9 8.1 0.0 2.6 2 0 0 2 2 2 0 Minor tail protein T DnaJ PF00226.31 EAN33903.1 - 1.1e-27 96.0 4.4 1.6e-27 95.4 4.4 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EAN33903.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein MCM PF00493.23 EAN33904.1 - 1.5e-40 138.7 0.5 5.7e-22 77.9 0.3 2.4 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 EAN33904.1 - 1.6e-12 47.4 0.7 2.8e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 MCM OB domain Mg_chelatase PF01078.21 EAN33904.1 - 6.2e-06 25.7 0.3 0.0052 16.2 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_lid PF17855.1 EAN33904.1 - 8.7e-05 22.9 0.1 0.00058 20.2 0.1 2.3 1 1 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 EAN33904.1 - 0.0027 17.7 0.4 0.18 11.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EAN33904.1 - 0.023 14.4 0.1 0.087 12.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF5547 PF17701.1 EAN33904.1 - 0.03 14.2 0.2 0.089 12.7 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5547) AAA_16 PF13191.6 EAN33904.1 - 0.033 14.6 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EAN33904.1 - 1.1 9.9 4.3 0.69 10.5 0.3 2.8 3 0 0 3 3 3 0 AAA domain HCNGP PF07818.13 EAN33904.1 - 3.5 8.3 6.6 4 8.1 0.2 3.2 3 0 0 3 3 3 0 HCNGP-like protein Hydrolase_4 PF12146.8 EAN33905.1 - 1.4e-23 83.4 0.0 1.1e-12 47.8 0.0 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EAN33905.1 - 0.006 16.4 0.0 0.69 9.7 0.0 2.6 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase VID27_PH PF17747.1 EAN33907.1 - 0.009 16.3 1.1 0.009 16.3 1.1 2.0 2 0 0 2 2 2 1 VID27 PH-like domain CAMSAP_CKK PF08683.11 EAN33909.1 - 0.0018 18.4 0.2 0.0093 16.1 0.0 2.3 2 0 0 2 2 2 1 Microtubule-binding calmodulin-regulated spectrin-associated Rtf2 PF04641.12 EAN33910.1 - 2.9e-46 158.0 0.0 5.8e-46 157.0 0.0 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 EAN33910.1 - 0.00017 21.7 0.2 0.00058 19.9 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EAN33910.1 - 0.00085 19.1 4.9 0.49 10.2 4.9 2.3 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EAN33910.1 - 0.0067 16.2 3.1 0.011 15.5 3.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Ribosomal_L37ae PF01780.19 EAN33910.1 - 0.049 13.7 0.3 0.1 12.7 0.3 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family zinc_ribbon_5 PF13719.6 EAN33910.1 - 0.067 13.0 0.1 0.067 13.0 0.1 2.4 3 0 0 3 3 3 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 EAN33910.1 - 0.3 11.0 2.9 4.7 7.2 0.1 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Nop10p PF04135.12 EAN33911.1 - 4.1e-23 81.2 0.2 4.6e-23 81.0 0.2 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF773 PF05600.12 EAN33912.1 - 2.7e-23 82.5 25.0 2.2e-17 63.0 7.1 2.8 2 1 1 3 3 3 2 CDK5 regulatory subunit-associated protein 3 Syntaxin PF00804.25 EAN33912.1 - 0.0017 18.0 22.2 0.0038 16.9 4.9 3.7 2 1 1 3 3 3 2 Syntaxin Spc42p PF11544.8 EAN33912.1 - 0.0039 17.2 0.6 0.0039 17.2 0.6 4.5 4 1 0 4 4 4 1 Spindle pole body component Spc42p DIX PF00778.17 EAN33912.1 - 0.055 13.3 0.3 2.7 7.9 0.1 2.7 2 0 0 2 2 2 0 DIX domain Lipase_GDSL PF00657.22 EAN33912.1 - 2.7 7.9 7.9 0.25 11.3 0.7 2.9 3 2 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase OmpH PF03938.14 EAN33912.1 - 2.7 8.3 14.8 0.046 14.1 0.9 4.0 4 1 1 5 5 5 0 Outer membrane protein (OmpH-like) Ribosomal_L14e PF01929.17 EAN33913.1 - 4.1e-23 81.7 6.2 5.1e-23 81.4 6.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 RVP PF00077.20 EAN33913.1 - 0.0099 16.2 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease SF-assemblin PF06705.11 EAN33914.1 - 6.3e-10 38.8 22.7 8.4e-10 38.4 22.7 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF1465 PF07323.12 EAN33914.1 - 0.021 14.7 1.7 0.036 13.9 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) Matrilin_ccoil PF10393.9 EAN33914.1 - 0.21 11.5 3.8 2.4 8.1 0.2 3.4 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin T3SchapCesA PF11439.8 EAN33914.1 - 0.21 11.7 6.6 0.66 10.2 0.4 2.9 2 1 1 3 3 3 0 Type III secretion system filament chaperone CesA CLZ PF16526.5 EAN33914.1 - 0.31 11.4 7.7 0.16 12.3 2.1 3.2 2 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cluap1 PF10234.9 EAN33914.1 - 0.56 9.6 13.3 0.026 13.9 7.1 1.8 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF1515 PF07439.11 EAN33914.1 - 0.9 9.6 5.2 2.7 8.1 0.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) SlyX PF04102.12 EAN33914.1 - 1.5 9.5 5.6 14 6.4 0.1 3.1 1 1 1 2 2 2 0 SlyX LOH1CR12 PF10158.9 EAN33914.1 - 1.9 8.5 9.4 1.1 9.3 1.5 3.0 1 1 1 3 3 3 0 Tumour suppressor protein DUF1664 PF07889.12 EAN33914.1 - 2.3 8.3 11.4 0.23 11.5 2.5 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CREPT PF16566.5 EAN33914.1 - 2.6 8.2 14.5 0.57 10.3 9.7 2.2 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PMC2NT PF08066.12 EAN33914.1 - 3.6 8.3 9.8 9.8 7.0 0.5 3.0 2 1 0 3 3 3 0 PMC2NT (NUC016) domain DUF16 PF01519.16 EAN33914.1 - 7.7 7.1 15.4 4.2 7.9 6.2 3.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 ATP-grasp_2 PF08442.10 EAN33915.1 - 6.9e-56 189.0 0.1 1.1e-55 188.4 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EAN33915.1 - 1.8e-20 73.3 0.0 3.3e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EAN33915.1 - 0.00068 19.1 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EAN33915.1 - 0.00083 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain HU-CCDC81_euk_1 PF14908.6 EAN33915.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 Pkinase PF00069.25 EAN33916.1 - 2e-67 227.3 0.0 2.9e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN33916.1 - 4.6e-29 101.5 0.0 7.9e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAN33916.1 - 1.8e-06 27.1 1.0 6.3e-06 25.4 1.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAN33916.1 - 0.011 15.0 0.2 0.083 12.2 0.1 2.5 1 1 1 2 2 2 0 Kinase-like Kdo PF06293.14 EAN33916.1 - 0.02 14.3 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAN33916.1 - 0.067 13.1 0.1 6.4 6.6 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FAINT PF04385.15 EAN33918.1 - 0.14 12.2 1.0 8 6.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function, DUF529 MMR_HSR1 PF01926.23 EAN33919.1 - 6.4e-17 61.7 0.3 6.3e-14 52.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EAN33919.1 - 5e-07 29.4 0.2 1.9e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAN33919.1 - 6.2e-07 29.5 0.1 0.015 15.2 0.0 2.6 1 1 1 2 2 2 2 RsgA GTPase Roc PF08477.13 EAN33919.1 - 0.0024 18.1 0.2 2.1 8.6 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EAN33919.1 - 0.01 16.4 0.0 0.01 16.4 0.0 2.7 2 1 0 2 2 2 0 ABC transporter rpo132 PF12415.8 EAN33919.1 - 0.1 11.9 0.3 1.1 8.6 0.0 2.6 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase AAA_16 PF13191.6 EAN33919.1 - 0.13 12.6 0.2 1.9 8.8 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain Ribosomal_L17 PF01196.19 EAN33920.1 - 2.9e-16 60.1 0.0 5.7e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 COX2 PF00116.20 EAN33921.1 - 2.6e-42 143.5 0.0 3.2e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain CCDC53 PF10152.9 EAN33922.1 - 0.0098 16.3 2.1 0.049 14.1 1.4 2.1 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex FAM76 PF16046.5 EAN33922.1 - 0.015 14.7 3.9 0.025 14.0 3.9 1.3 1 0 0 1 1 1 0 FAM76 protein DUF16 PF01519.16 EAN33922.1 - 0.79 10.2 6.3 0.66 10.5 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function DUF16 ISG65-75 PF11727.8 EAN33922.1 - 0.83 8.8 3.1 0.89 8.7 1.0 1.8 2 0 0 2 2 2 0 Invariant surface glycoprotein FAINT PF04385.15 EAN33923.1 - 3.6e-31 107.1 23.8 3.9e-08 33.2 0.1 6.2 6 0 0 6 6 6 5 Domain of unknown function, DUF529 Diphthamide_syn PF01866.17 EAN33924.1 - 2.4e-27 96.2 0.2 3.5e-27 95.6 0.2 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ribosomal_L27A PF00828.19 EAN33924.1 - 1.4e-11 45.2 0.3 4.7e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Proteasom_PSMB PF10508.9 EAN33924.1 - 0.019 13.5 0.1 0.033 12.7 0.1 1.3 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Osmo_CC PF08946.10 EAN33924.1 - 0.76 10.1 3.8 27 5.1 0.0 2.6 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Adaptin_N PF01602.20 EAN33925.1 - 5.3e-45 154.0 21.5 1e-44 153.0 21.1 1.5 1 1 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 EAN33925.1 - 2.9e-25 88.7 0.4 1.6e-24 86.3 0.1 2.5 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EAN33925.1 - 1.1e-17 64.3 0.7 2.8e-17 62.9 0.7 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region RTP1_C1 PF10363.9 EAN33925.1 - 0.0012 19.0 0.1 0.02 15.1 0.0 2.9 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EAN33925.1 - 0.013 15.5 13.3 0.014 15.5 0.1 3.5 2 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAN33925.1 - 0.04 14.2 0.2 10 6.7 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Fmp27_WPPW PF10359.9 EAN33925.1 - 0.051 12.4 0.2 0.086 11.7 0.2 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mei5_like PF17021.5 EAN33925.1 - 0.27 11.3 5.3 4.6 7.3 0.1 3.8 4 0 0 4 4 4 0 Putative double-strand recombination repair-like ParcG PF10274.9 EAN33925.1 - 0.49 10.5 10.8 4.2 7.4 1.2 4.0 2 1 2 4 4 4 0 Parkin co-regulated protein Mrx7 PF10906.8 EAN33926.1 - 0.0099 16.1 0.4 0.039 14.2 0.4 2.0 1 0 0 1 1 1 1 MIOREX complex component 7 FAST_1 PF06743.15 EAN33926.1 - 0.059 13.3 10.5 0.1 12.6 0.0 5.2 5 1 1 6 6 6 0 FAST kinase-like protein, subdomain 1 DUF445 PF04286.12 EAN33926.1 - 0.14 11.9 3.6 3.6 7.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) VPS28 PF03997.12 EAN33929.1 - 4.4e-33 114.5 0.3 5.1e-33 114.3 0.3 1.0 1 0 0 1 1 1 1 VPS28 protein Asp PF00026.23 EAN33930.1 - 6.3e-55 186.8 2.3 8.5e-55 186.4 2.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAN33930.1 - 6.5e-15 55.8 5.6 1.6e-09 38.3 0.1 2.4 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal His_Phos_2 PF00328.22 EAN33932.1 - 2.9e-45 155.3 2.2 4.5e-31 108.6 0.0 3.4 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EAN33932.1 - 1.2e-31 108.7 0.1 3e-31 107.4 0.1 1.8 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EAN33932.1 - 0.00037 20.1 0.0 0.00094 18.8 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain CK2S PF15011.6 EAN33932.1 - 0.2 11.5 0.7 4.1 7.3 0.3 2.6 2 0 0 2 2 2 0 Casein Kinase 2 substrate PTPA PF03095.15 EAN33933.1 - 1.2e-52 179.3 0.7 1.6e-52 178.9 0.7 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Herpes_LMP1 PF05297.11 EAN33934.1 - 8.6 5.4 11.2 11 5.0 11.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) zf-RING_11 PF17123.5 EAN33935.1 - 3.5e-11 42.6 3.9 5.3e-10 38.9 4.0 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 EAN33935.1 - 2.1e-10 40.7 8.4 2.1e-10 40.7 8.4 2.6 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 EAN33935.1 - 1e-07 32.1 7.9 5.8e-07 29.7 7.9 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAN33935.1 - 1.5e-07 31.2 2.5 1.5e-07 31.2 2.5 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAN33935.1 - 5.8e-07 29.2 8.2 5.8e-07 29.2 8.2 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN33935.1 - 4.9e-06 26.5 4.3 5.7e-06 26.3 1.7 2.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAN33935.1 - 9.7e-05 22.3 9.8 0.0001 22.2 5.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain PagP PF07017.11 EAN33935.1 - 0.011 15.1 0.4 0.18 11.2 0.1 2.1 1 1 0 2 2 2 0 Antimicrobial peptide resistance and lipid A acylation protein PagP zf-ANAPC11 PF12861.7 EAN33935.1 - 0.061 13.4 6.4 0.27 11.3 6.4 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EAN33935.1 - 0.088 12.7 9.7 0.073 12.9 6.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 EAN33936.1 - 3.5e-12 46.6 0.1 1.9e-10 41.0 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 EAN33936.1 - 7.1e-06 26.3 0.0 2.4e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 EAN33936.1 - 1e-05 25.4 0.0 7.5e-05 22.6 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAN33936.1 - 4.9e-05 23.6 0.0 0.00029 21.1 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAN33936.1 - 0.00028 21.2 0.0 0.00094 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EAN33936.1 - 0.0014 18.0 0.5 0.004 16.5 0.1 1.9 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 EAN33936.1 - 0.011 15.2 1.3 0.38 10.2 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 EAN33936.1 - 0.013 14.6 0.0 0.038 13.0 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EAN33936.1 - 0.015 15.0 0.0 0.046 13.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pentapeptide_2 PF01469.18 EAN33936.1 - 0.02 14.8 12.7 0.042 13.7 12.7 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) PhoH PF02562.16 EAN33936.1 - 0.025 14.0 1.2 0.063 12.7 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 EAN33936.1 - 0.035 13.8 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EAN33936.1 - 0.22 12.0 0.0 0.22 12.0 0.0 4.3 4 0 0 4 4 4 0 AAA domain AAA_11 PF13086.6 EAN33936.1 - 5.8 6.6 10.0 7.3 6.3 0.0 4.1 4 0 0 4 4 4 0 AAA domain Treacle PF03546.14 EAN33937.1 - 0.025 13.4 1.2 0.025 13.4 1.2 1.0 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle U79_P34 PF03064.16 EAN33937.1 - 0.042 13.2 1.6 0.043 13.2 1.6 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RAP-1 PF03085.15 EAN33938.1 - 3e-104 348.0 21.1 2.7e-77 259.8 3.4 2.2 2 0 0 2 2 2 2 Rhoptry-associated protein 1 (RAP-1) Cornifin PF02389.15 EAN33938.1 - 0.0096 16.1 1.7 0.017 15.3 1.7 1.4 1 0 0 1 1 1 1 Cornifin (SPRR) family RAP-1 PF03085.15 EAN33939.1 - 4.7e-124 412.8 15.3 2.3e-104 348.4 7.0 3.0 2 1 0 2 2 2 2 Rhoptry-associated protein 1 (RAP-1) PXA PF02194.15 EAN33939.1 - 0.031 14.2 1.2 0.057 13.4 0.0 2.1 2 0 0 2 2 2 0 PXA domain DUF3484 PF11983.8 EAN33939.1 - 1.1 10.4 6.4 0.13 13.4 1.2 2.2 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch OmpH PF03938.14 EAN33939.1 - 1.1 9.6 14.9 3.7 7.9 14.9 1.9 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1690 PF07956.11 EAN33939.1 - 6.7 7.1 16.7 1.2 9.5 12.5 1.9 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) RAP-1 PF03085.15 EAN33940.1 - 9.5e-15 55.0 2.6 1.9e-14 54.0 2.6 1.5 1 1 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) RAP-1 PF03085.15 EAN33941.1 - 1.9e-09 37.6 14.7 0.00054 19.7 4.2 3.3 3 1 0 3 3 3 3 Rhoptry-associated protein 1 (RAP-1) RAP-1 PF03085.15 EAN33942.1 - 8.2e-138 457.9 46.2 8.1e-70 235.3 16.1 3.1 1 1 2 3 3 3 3 Rhoptry-associated protein 1 (RAP-1) C4bp_oligo PF18453.1 EAN33942.1 - 0.083 13.1 0.2 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Oligomerization domain of C4b-binding protein alpha Imm5 PF14423.6 EAN33942.1 - 0.67 10.2 3.0 9.6 6.4 0.1 3.0 3 0 0 3 3 3 0 Immunity protein Imm5 DUF4806 PF16064.5 EAN33942.1 - 1.3 9.4 6.2 9.6 6.6 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4806) HEAT_2 PF13646.6 EAN33943.1 - 1.6e-18 66.8 0.1 8.6e-10 38.9 0.0 2.6 2 0 0 2 2 2 2 HEAT repeats HEAT_PBS PF03130.16 EAN33943.1 - 1.3e-10 40.9 0.1 0.013 16.1 0.0 5.8 6 0 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT PF02985.22 EAN33943.1 - 6.2e-08 32.2 4.7 2.3 8.7 0.0 5.3 5 0 0 5 5 5 4 HEAT repeat Cnd1 PF12717.7 EAN33943.1 - 2.5e-05 24.4 0.3 0.071 13.2 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF2274 PF10038.9 EAN33943.1 - 0.029 14.8 0.0 0.093 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) HEAT_EZ PF13513.6 EAN33943.1 - 0.059 13.9 0.1 11 6.6 0.0 3.4 3 1 1 4 4 4 0 HEAT-like repeat DnaJ_C PF01556.18 EAN33944.1 - 1.4e-38 132.3 0.1 1.9e-38 131.9 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAN33944.1 - 6.6e-24 83.8 2.1 1.1e-23 83.1 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EAN33944.1 - 7.6e-14 51.8 18.1 7.6e-14 51.8 18.1 1.7 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 EAN33944.1 - 3.6e-05 23.6 7.7 0.00021 21.2 1.3 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein CBP_BcsR PF10945.8 EAN33944.1 - 0.25 10.8 0.4 0.5 9.9 0.4 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR HypA PF01155.19 EAN33944.1 - 0.51 10.4 9.6 5.7 7.0 0.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Tnp_zf-ribbon_2 PF13842.6 EAN33944.1 - 1.3 9.9 15.2 17 6.3 0.2 3.6 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon DZR PF12773.7 EAN33944.1 - 6.2 6.9 11.6 56 3.9 11.6 2.2 1 1 0 1 1 1 0 Double zinc ribbon eIF2A PF08662.11 EAN33945.1 - 4.9e-71 238.6 0.5 1.6e-70 237.0 0.1 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RPN1_RPN2_N PF17781.1 EAN33947.1 - 2.8e-40 138.6 1.0 1.5e-39 136.2 1.0 2.0 1 1 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EAN33947.1 - 4.8e-20 71.3 0.2 1.2e-19 70.1 0.2 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EAN33947.1 - 1.5e-14 53.5 9.5 0.00012 22.4 0.1 6.7 7 0 0 7 7 7 3 Proteasome/cyclosome repeat DDHD PF02862.17 EAN33947.1 - 2.2 8.4 8.7 0.22 11.6 1.0 2.6 3 0 0 3 3 3 0 DDHD domain DUF966 PF06136.13 EAN33947.1 - 6 6.5 12.2 0.3 10.8 6.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF966) RIFIN PF02009.16 EAN33947.1 - 9.9 5.9 9.7 23 4.7 9.7 1.5 1 0 0 1 1 1 0 Rifin zf-Tim10_DDP PF02953.15 EAN33948.1 - 0.02 14.6 0.6 0.072 12.8 0.6 2.1 1 0 0 1 1 1 0 Tim10/DDP family zinc finger bVLRF1 PF18826.1 EAN33948.1 - 0.23 11.3 0.4 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 bacteroidetes VLRF1 release factor CRR7 PF12095.8 EAN33948.1 - 0.28 11.7 3.3 2.7 8.5 0.7 3.8 2 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 AAA PF00004.29 EAN33949.1 - 1e-40 139.2 0.0 2e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAN33949.1 - 1.3e-09 37.7 0.1 3.8e-09 36.2 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EAN33949.1 - 1.8e-05 25.0 0.1 0.0097 16.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EAN33949.1 - 3.1e-05 24.0 0.0 0.0001 22.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAN33949.1 - 5.1e-05 23.7 0.1 0.00092 19.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 EAN33949.1 - 6.2e-05 23.2 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EAN33949.1 - 0.00064 19.5 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EAN33949.1 - 0.0025 17.0 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EAN33949.1 - 0.008 15.7 0.0 0.027 14.0 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EAN33949.1 - 0.0089 16.6 0.0 0.02 15.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 EAN33949.1 - 0.013 15.7 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAN33949.1 - 0.02 15.0 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EAN33949.1 - 0.03 14.1 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAN33949.1 - 0.042 13.6 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EAN33949.1 - 0.043 14.2 0.0 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 EAN33949.1 - 0.062 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EAN33949.1 - 0.096 12.0 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 EAN33949.1 - 0.16 11.9 0.0 8.2 6.3 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EAN33949.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EAN33949.1 - 0.17 11.6 0.0 0.5 10.1 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Adap_comp_sub PF00928.21 EAN33950.1 - 2.8e-77 259.6 0.6 3.6e-77 259.3 0.6 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EAN33950.1 - 8.1e-07 29.1 1.3 1.5e-06 28.2 0.6 1.8 2 0 0 2 2 2 1 Clathrin adaptor complex small chain EcoEI_R_C PF08463.10 EAN33951.1 - 0.081 13.0 0.7 0.3 11.2 0.2 2.1 2 0 0 2 2 2 0 EcoEI R protein C-terminal DUF4822 PF16103.5 EAN33951.1 - 0.092 13.0 2.8 0.091 13.0 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4822) DUF4268 PF14088.6 EAN33951.1 - 0.12 12.2 1.6 6.7 6.6 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4268) FAST_1 PF06743.15 EAN33951.1 - 0.46 10.5 5.3 6.8 6.7 0.6 3.4 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 TPT PF03151.16 EAN33953.1 - 6e-29 101.3 10.7 1.2e-28 100.3 10.7 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EAN33953.1 - 6.8e-05 23.1 9.1 0.019 15.1 0.7 3.0 3 0 0 3 3 3 2 EamA-like transporter family Flavi_NS4A PF01350.17 EAN33953.1 - 0.9 9.5 3.8 13 5.7 0.2 2.4 1 1 1 2 2 2 0 Flavivirus non-structural protein NS4A Ribosomal_S16 PF00886.19 EAN33954.1 - 1.3e-11 44.4 0.0 6e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S16 Secretin PF00263.21 EAN33955.1 - 0.24 11.0 5.0 0.39 10.3 1.9 2.3 2 0 0 2 2 2 0 Bacterial type II and III secretion system protein MID_MedPIWI PF18296.1 EAN33957.1 - 0.51 10.1 5.9 0.068 12.9 1.9 1.5 2 0 0 2 2 2 0 MID domain of medPIWI E1-E2_ATPase PF00122.20 EAN33958.1 - 2.1e-48 164.2 5.1 2.1e-48 164.2 5.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAN33958.1 - 6.4e-34 117.2 0.0 6.4e-34 117.2 0.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EAN33958.1 - 2.9e-20 73.4 0.4 4e-15 56.7 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAN33958.1 - 1.9e-17 62.7 0.0 3.8e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EAN33958.1 - 3.9e-14 52.5 0.1 1.2e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAN33958.1 - 0.003 17.3 1.7 0.067 12.9 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FliMN_C PF01052.20 EAN33958.1 - 0.012 15.6 2.6 0.018 15.0 1.1 2.1 3 0 0 3 3 3 0 Type III flagellar switch regulator (C-ring) FliN C-term DUF5362 PF17319.2 EAN33958.1 - 0.036 13.9 0.4 0.036 13.9 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5362) DUF565 PF04483.12 EAN33958.1 - 0.058 13.9 0.1 0.2 12.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF565) Flu_M2 PF00599.17 EAN33958.1 - 0.066 13.3 0.7 5.6 7.1 0.0 2.7 2 0 0 2 2 2 0 Influenza Matrix protein (M2) SpoIIM PF01944.17 EAN33958.1 - 0.18 11.8 0.0 0.18 11.8 0.0 3.9 5 0 0 5 5 5 0 Stage II sporulation protein M ubiquitin PF00240.23 EAN33959.1 - 6.9e-71 234.0 4.2 1.1e-34 117.9 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EAN33959.1 - 9.3e-35 118.3 4.6 1.2e-16 60.3 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAN33959.1 - 6.2e-14 52.2 0.8 3.1e-05 24.3 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 EAN33959.1 - 1.8e-08 34.2 0.3 0.0068 16.3 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAN33959.1 - 5.5e-08 33.1 0.3 0.013 15.8 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAN33959.1 - 5.9e-08 32.8 0.3 0.019 15.0 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAN33959.1 - 7e-06 26.6 0.0 0.17 12.4 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EAN33959.1 - 4.8e-05 23.3 6.8 9.2 6.4 0.0 4.0 4 0 0 4 4 4 2 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 EAN33959.1 - 0.00022 21.1 0.0 0.64 9.8 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain DUF2870 PF11069.8 EAN33959.1 - 0.013 15.9 0.1 11 6.5 0.0 2.8 2 2 2 4 4 4 0 Protein of unknown function (DUF2870) RBD PF02196.15 EAN33959.1 - 0.028 14.5 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Raf-like Ras-binding domain FERM_f0 PF16511.5 EAN33959.1 - 0.045 14.0 2.0 32 4.9 0.1 3.7 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM DUF3861 PF12977.7 EAN33959.1 - 0.046 13.9 0.1 11 6.2 0.0 2.2 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) FlgD_ig PF13860.6 EAN33959.1 - 0.11 12.4 0.5 21 5.1 0.1 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain TmoB PF06234.12 EAN33959.1 - 0.11 12.6 0.3 25 5.0 0.0 2.7 2 2 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 EAN33959.1 - 0.14 12.3 0.5 1.6 8.9 0.0 2.4 3 0 0 3 3 3 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EAN33959.1 - 0.16 11.4 0.0 6.4 6.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF969) MCM PF00493.23 EAN33960.1 - 2.9e-93 311.1 0.7 6.9e-93 309.9 0.1 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EAN33960.1 - 1.8e-27 95.7 4.5 2.1e-27 95.4 2.1 2.1 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 EAN33960.1 - 2.4e-26 92.0 2.2 5.5e-26 90.8 2.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EAN33960.1 - 3.9e-06 26.4 0.0 1.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EAN33960.1 - 0.0032 17.2 0.1 0.009 15.7 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 EAN33960.1 - 0.0067 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAN33960.1 - 0.011 15.7 0.0 0.033 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Amino_oxidase PF01593.24 EAN33961.1 - 2.2e-37 129.4 0.0 4.2e-27 95.5 0.0 2.7 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase zf-HC5HC2H_2 PF13832.6 EAN33961.1 - 6.7e-12 45.5 35.5 1.2e-05 25.4 2.6 6.5 6 0 0 6 6 6 4 PHD-zinc-finger like domain NAD_binding_8 PF13450.6 EAN33961.1 - 3.8e-10 39.8 0.0 9.5e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-HC5HC2H PF13771.6 EAN33961.1 - 1.2e-08 35.1 39.5 0.00052 20.2 0.4 6.7 6 1 0 6 6 6 5 PHD-like zinc-binding domain PHD PF00628.29 EAN33961.1 - 1.7e-05 24.6 18.8 0.00019 21.3 2.0 5.7 5 0 0 5 5 5 2 PHD-finger Pyr_redox_2 PF07992.14 EAN33961.1 - 3.4e-05 23.2 0.0 6.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PHD_2 PF13831.6 EAN33961.1 - 0.00017 21.0 1.0 0.00017 21.0 1.0 4.7 4 1 0 4 4 4 1 PHD-finger Thi4 PF01946.17 EAN33961.1 - 0.00036 19.9 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EAN33961.1 - 0.0039 16.8 0.2 0.0068 16.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAN33961.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EAN33961.1 - 0.082 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF5456 PF17539.2 EAN33961.1 - 7.3 6.4 7.6 1.1 9.1 0.6 3.1 4 0 0 4 4 4 0 Family of unknown function (DUF5456) MutS_I PF01624.20 EAN33962.1 - 1.5e-07 31.6 0.0 5e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 MutS domain I GIY-YIG PF01541.24 EAN33962.1 - 0.0052 17.0 1.5 0.04 14.2 0.1 2.7 2 0 0 2 2 2 1 GIY-YIG catalytic domain ALS2CR8 PF15299.6 EAN33962.1 - 0.015 15.2 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Iron_traffic PF04362.14 EAN33962.1 - 0.054 13.2 0.3 0.31 10.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking Ribonuc_red_sm PF00268.21 EAN33963.1 - 7.4e-113 376.6 2.5 8.6e-113 376.4 2.5 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NMT PF01233.19 EAN33963.1 - 0.0014 18.5 0.2 0.003 17.4 0.2 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain EF1G PF00647.19 EAN33963.1 - 0.072 13.1 2.9 0.61 10.2 0.1 2.4 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain DUF4744 PF15918.5 EAN33963.1 - 0.21 12.4 0.0 0.45 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) GTP_EFTU PF00009.27 EAN33964.1 - 1.1e-52 178.4 0.0 1.5e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EAN33964.1 - 5.1e-40 136.3 0.5 2e-39 134.4 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EAN33964.1 - 1.8e-12 47.5 0.5 5.8e-12 45.8 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAN33964.1 - 0.00022 21.3 0.6 0.008 16.2 0.1 3.0 2 2 0 2 2 2 1 50S ribosome-binding GTPase tRNA-synt_1c PF00749.21 EAN33965.1 - 3.5e-61 206.8 0.7 1.4e-38 132.6 0.0 2.4 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain Pkinase PF00069.25 EAN33966.1 - 2.9e-78 262.9 0.0 3.3e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN33966.1 - 1.9e-34 119.1 0.0 2.4e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAN33966.1 - 0.00068 18.7 0.0 0.0033 16.4 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAN33966.1 - 0.0031 16.9 0.0 0.01 15.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EAN33966.1 - 0.004 16.5 0.1 0.011 15.1 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAN33966.1 - 0.013 15.4 0.1 0.024 14.6 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EAN33966.1 - 0.037 13.6 0.0 0.23 11.0 0.0 2.0 1 1 1 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 EAN33966.1 - 0.15 11.1 0.0 0.32 10.0 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 DnaJ PF00226.31 EAN33967.1 - 1.2e-22 79.8 2.6 2.7e-22 78.6 2.6 1.6 1 0 0 1 1 1 1 DnaJ domain GLTSCR1 PF15249.6 EAN33967.1 - 0.0045 17.4 1.9 0.011 16.2 1.9 1.7 1 1 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein RCC1 PF00415.18 EAN33968.1 - 5.1e-27 94.3 13.5 6.7e-11 42.6 0.1 8.1 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAN33968.1 - 1.3e-23 82.2 22.1 6.9e-09 35.3 0.2 6.4 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 EAN33968.1 - 0.0092 15.9 0.6 6.2 7.0 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Pkinase PF00069.25 EAN33969.1 - 1.6e-09 37.5 13.6 2.2e-05 24.0 2.7 5.0 6 1 0 6 6 6 3 Protein kinase domain Pkinase_Tyr PF07714.17 EAN33969.1 - 4.7e-05 22.8 0.9 0.4 9.9 0.2 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase UQ_con PF00179.26 EAN33970.1 - 1.4e-50 170.6 0.1 1.6e-50 170.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAN33970.1 - 8.1e-05 22.9 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EAN33970.1 - 0.00026 20.7 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Tim17 PF02466.19 EAN33971.1 - 1.5e-16 60.8 2.4 2.1e-16 60.3 2.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UEV PF05743.13 EAN33972.1 - 4.7e-28 97.5 0.7 8.1e-28 96.7 0.0 1.7 2 0 0 2 2 2 1 UEV domain UQ_con PF00179.26 EAN33972.1 - 0.00015 21.4 0.4 0.00039 20.1 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Glutaredoxin PF00462.24 EAN33973.1 - 9.9e-15 54.5 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Exonuc_VII_L PF02601.15 EAN33974.1 - 0.0084 15.7 24.1 0.0084 15.7 24.1 3.4 3 1 1 4 4 4 2 Exonuclease VII, large subunit Sas10 PF09368.10 EAN33977.1 - 1.7e-21 76.5 7.4 1.7e-21 76.5 7.4 2.7 2 1 0 2 2 2 1 Sas10 C-terminal domain DUF3106 PF11304.8 EAN33977.1 - 0.22 12.0 6.1 2 8.9 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) EF-1_beta_acid PF10587.9 EAN33977.1 - 1.6 9.2 8.0 1 9.9 2.5 2.7 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region DUF4407 PF14362.6 EAN33977.1 - 2.5 7.3 4.6 3 7.1 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sas10_Utp3 PF04000.15 EAN33978.1 - 4.5e-14 52.8 0.7 4.5e-14 52.8 0.7 3.6 2 1 1 3 3 3 1 Sas10/Utp3/C1D family GARP PF16731.5 EAN33978.1 - 0.073 12.7 8.1 2.7 7.6 3.4 2.3 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Filamin PF00630.19 EAN33979.1 - 2.2e-16 60.5 0.1 3.1e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 Filamin/ABP280 repeat Chordopox_A15 PF05846.12 EAN33979.1 - 1.8 8.8 4.7 6.8 7.0 0.1 3.8 4 1 0 4 4 4 0 Chordopoxvirus A15 protein tRNA_anti-codon PF01336.25 EAN33982.1 - 0.072 13.1 0.0 0.2 11.7 0.0 1.7 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain ACBP PF00887.19 EAN33983.1 - 4.8e-16 58.7 0.3 6.5e-16 58.3 0.3 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein RE_TaqI PF09573.10 EAN33983.1 - 0.047 13.5 0.3 0.063 13.1 0.3 1.2 1 0 0 1 1 1 0 TaqI restriction endonuclease Nop PF01798.18 EAN33985.1 - 5.9e-78 261.5 0.0 5.9e-78 261.5 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EAN33985.1 - 4.1e-19 68.7 0.0 4.1e-19 68.7 0.0 3.3 4 0 0 4 4 4 1 NOP5NT (NUC127) domain BCDHK_Adom3 PF10436.9 EAN33985.1 - 0.056 13.3 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase GIT_SHD PF08518.11 EAN33986.1 - 0.059 13.0 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT PRANC PF09372.10 EAN33986.1 - 0.087 13.2 0.0 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 PRANC domain MOZ_SAS PF01853.18 EAN33987.1 - 7.8e-72 240.7 0.2 1.1e-71 240.2 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EAN33987.1 - 6.4e-21 73.7 1.7 1.6e-20 72.5 1.7 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EAN33987.1 - 4.2e-10 39.3 0.2 9.3e-10 38.2 0.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain FliT PF05400.13 EAN33989.1 - 0.094 13.5 0.1 0.64 10.9 0.2 1.9 2 0 0 2 2 2 0 Flagellar protein FliT Peptidase_M16_C PF05193.21 EAN33990.1 - 2.7e-14 53.6 1.7 2.6e-09 37.3 0.2 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EAN33990.1 - 4.4e-10 39.7 0.1 5.5e-08 32.9 0.0 2.8 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) HSP90 PF00183.18 EAN33991.1 - 7.2e-102 341.9 18.2 3.5e-99 333.0 14.3 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 EAN33991.1 - 1.8e-10 40.8 0.0 3.9e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EAN33991.1 - 4.4e-08 33.6 0.0 9.9e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1840 PF08895.11 EAN33991.1 - 0.084 13.2 0.2 6.2 7.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) TFIID_NTD2 PF04494.15 EAN33991.1 - 3.4 7.9 8.8 7.1 6.9 0.2 3.7 4 0 0 4 4 4 0 WD40 associated region in TFIID subunit, NTD2 domain DUF4473 PF14747.6 EAN33991.1 - 5.7 7.6 7.4 7.8 7.1 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) Clat_adaptor_s PF01217.20 EAN33992.1 - 8.3e-46 155.5 4.7 9.4e-46 155.3 4.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DNA_mis_repair PF01119.19 EAN33994.1 - 1.9e-19 69.5 1.8 1.9e-19 69.5 1.8 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain Mlh1_C PF16413.5 EAN33994.1 - 3.1e-15 56.3 4.9 2.5e-13 50.0 4.9 2.7 1 1 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus HATPase_c_3 PF13589.6 EAN33994.1 - 4.9e-12 45.8 0.0 1.4e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EAN33994.1 - 0.00015 22.2 0.3 0.00056 20.4 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ras PF00071.22 EAN33995.1 - 4.9e-49 166.0 0.0 5.9e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAN33995.1 - 5.1e-31 107.4 0.0 1e-30 106.4 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAN33995.1 - 2e-12 46.9 0.0 2.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAN33995.1 - 2.4e-05 24.4 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EAN33995.1 - 0.0012 19.2 0.1 0.0053 17.1 0.1 1.9 1 1 0 1 1 1 1 RNA helicase RsgA_GTPase PF03193.16 EAN33995.1 - 0.0025 17.7 0.0 0.41 10.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 EAN33995.1 - 0.0051 16.2 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EAN33995.1 - 0.0077 16.6 0.1 0.012 16.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain ArgoMid PF16487.5 EAN33995.1 - 0.011 16.0 0.1 0.024 14.9 0.1 1.6 1 1 0 1 1 1 0 Mid domain of argonaute AAA_7 PF12775.7 EAN33995.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 EAN33995.1 - 0.016 14.7 0.4 0.15 11.5 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EAN33995.1 - 0.042 13.0 0.5 1.4 8.0 0.2 2.7 2 1 1 3 3 3 0 G-protein alpha subunit NB-ARC PF00931.22 EAN33995.1 - 0.046 12.9 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 EAN33995.1 - 0.073 13.6 0.1 0.91 10.0 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Septin PF00735.18 EAN33995.1 - 0.095 12.0 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin TniB PF05621.11 EAN33995.1 - 0.12 11.8 0.0 0.47 9.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 EAN33995.1 - 0.13 12.6 0.0 0.47 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EAN33995.1 - 0.15 12.0 0.1 0.38 10.7 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 EAN33995.1 - 0.15 12.0 0.1 0.42 10.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EAN33995.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EAN33995.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbtB PF09489.10 EAN33996.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Cadherin-like PF12733.7 EAN33997.1 - 1e-05 26.0 0.2 0.00026 21.4 0.0 3.1 2 1 0 2 2 2 1 Cadherin-like beta sandwich domain P53_tetramer PF07710.11 EAN33997.1 - 0.17 11.3 2.0 6.6 6.2 1.0 2.5 2 0 0 2 2 2 0 P53 tetramerisation motif tRNA-synt_1b PF00579.25 EAN33998.1 - 4.1e-35 121.5 0.0 1.4e-33 116.5 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3273 PF11677.8 EAN33999.1 - 6.5e-96 320.7 16.2 8.3e-96 320.4 16.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Clat_adaptor_s PF01217.20 EAN34001.1 - 1.1e-39 135.6 2.6 1.2e-39 135.4 2.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 EAN34001.1 - 0.039 14.0 0.1 0.049 13.6 0.1 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DEAD PF00270.29 EAN34003.1 - 7.5e-44 149.6 0.3 2e-43 148.2 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN34003.1 - 5.6e-34 116.8 0.1 1.3e-32 112.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN34003.1 - 2.2e-06 27.8 0.0 5.6e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EAN34003.1 - 0.00092 19.0 0.0 0.0016 18.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAN34003.1 - 0.013 15.9 0.1 0.029 14.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 EAN34003.1 - 0.034 13.5 0.1 0.1 11.9 0.1 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PhoH PF02562.16 EAN34003.1 - 0.046 13.2 0.1 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 EAN34003.1 - 0.082 12.7 0.2 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 EAN34003.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase TFB6 PF17110.5 EAN34005.1 - 0.0048 16.7 0.6 0.0093 15.7 0.1 1.7 2 0 0 2 2 2 1 Subunit 11 of the general transcription factor TFIIH HI0933_like PF03486.14 EAN34006.1 - 0.044 12.5 0.2 0.046 12.4 0.2 1.0 1 0 0 1 1 1 0 HI0933-like protein CTD PF12815.7 EAN34008.1 - 2.6 8.7 4.6 5.1 7.7 3.3 2.0 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Glutaredoxin2_C PF04399.13 EAN34009.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain CAF1C_H4-bd PF12265.8 EAN34010.1 - 5.6e-18 65.0 0.5 2.6e-17 62.8 0.0 2.4 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EAN34010.1 - 4.1e-09 36.9 16.5 0.033 15.1 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN34010.1 - 3.7e-06 27.1 1.0 0.096 13.0 0.0 4.4 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAN34010.1 - 0.001 18.5 3.1 0.58 9.4 0.3 2.7 2 1 0 2 2 2 2 WD40-like domain CPSF_A PF03178.15 EAN34010.1 - 0.0038 16.6 0.7 0.047 13.0 0.6 2.3 2 0 0 2 2 2 1 CPSF A subunit region RAB3GAP2_N PF14655.6 EAN34010.1 - 0.018 14.4 0.1 0.033 13.4 0.1 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2415 PF10313.9 EAN34010.1 - 0.056 13.4 0.2 1.4 8.9 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) BBS2_Mid PF14783.6 EAN34010.1 - 0.11 12.5 0.5 4.1 7.5 0.2 3.2 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 EAN34011.1 - 5.4e-06 27.0 3.8 0.81 10.7 0.0 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN34011.1 - 5e-05 23.5 0.1 0.58 10.5 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EAN34011.1 - 0.0088 15.3 0.1 0.17 11.1 0.1 2.2 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Paralemmin PF03285.15 EAN34011.1 - 0.099 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Paralemmin Myosin_head PF00063.21 EAN34012.1 - 1.1e-185 618.7 18.6 1.9e-185 618.0 18.6 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 EAN34012.1 - 1.2e-18 65.0 15.9 7.7e-05 22.2 0.2 5.6 5 0 0 5 5 5 4 IQ calmodulin-binding motif AAA_16 PF13191.6 EAN34012.1 - 0.0037 17.7 0.8 0.045 14.1 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EAN34012.1 - 0.01 16.1 2.2 0.036 14.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain Myosin_N PF02736.19 EAN34012.1 - 0.014 15.2 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain JAKMIP_CC3 PF16034.5 EAN34012.1 - 0.05 13.5 13.9 0.057 13.4 10.8 2.6 2 0 0 2 2 2 0 JAKMIP CC3 domain DUF3037 PF11236.8 EAN34012.1 - 0.58 10.6 4.2 3.6 8.0 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3037) PI-PLC-X PF00388.19 EAN34013.1 - 2.3e-39 134.3 0.0 4.7e-39 133.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EAN34013.1 - 1.1e-21 77.3 0.0 3.4e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EAN34013.1 - 8.7e-12 45.2 0.1 2.7e-11 43.7 0.1 1.8 2 0 0 2 2 2 1 C2 domain Mcp5_PH PF12814.7 EAN34013.1 - 0.0056 16.8 0.1 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Pox_E10 PF04805.12 EAN34014.1 - 0.24 11.3 5.4 0.86 9.5 1.8 2.9 2 0 0 2 2 2 0 E10-like protein conserved region Utp14 PF04615.13 EAN34015.1 - 9.1e-24 84.1 8.8 1.6e-23 83.2 8.8 1.3 1 1 0 1 1 1 1 Utp14 protein Utp14 PF04615.13 EAN34016.1 - 1.6e-30 106.4 51.8 5.5e-24 84.8 23.7 3.0 1 1 2 3 3 3 2 Utp14 protein AP2 PF00847.20 EAN34018.1 - 3.3e-05 24.0 0.9 0.00013 22.1 0.7 2.0 2 0 0 2 2 2 1 AP2 domain Pkinase PF00069.25 EAN34019.1 - 4.5e-64 216.4 0.0 7.9e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN34019.1 - 1.2e-27 96.9 0.9 8.7e-27 94.0 0.9 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAN34019.1 - 6.6e-05 22.0 0.4 9.3e-05 21.5 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAN34019.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CLTH PF10607.9 EAN34020.1 - 8.3e-16 58.2 1.2 1.4e-15 57.5 1.2 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EAN34020.1 - 2.6e-12 46.9 1.4 8.2e-12 45.3 1.4 1.8 1 1 0 1 1 1 1 SPRY domain LisH PF08513.11 EAN34020.1 - 1e-06 28.4 0.1 2.5e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 LisH Ubie_methyltran PF01209.18 EAN34020.1 - 0.062 12.6 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Zn-ribbon_8 PF09723.10 EAN34021.1 - 0.092 12.9 0.7 0.23 11.6 0.2 1.8 2 0 0 2 2 2 0 Zinc ribbon domain Ank_2 PF12796.7 EAN34022.1 - 1.2e-32 112.3 3.1 1.1e-13 51.5 0.1 3.9 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAN34022.1 - 4.8e-21 74.9 1.2 3.5e-11 43.4 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Bromodomain PF00439.25 EAN34022.1 - 4.6e-20 71.5 0.1 1.1e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Ank_3 PF13606.6 EAN34022.1 - 2e-16 58.4 0.0 0.00017 21.7 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAN34022.1 - 7.8e-15 54.7 2.4 4.4e-06 26.9 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAN34022.1 - 2.9e-10 40.1 0.1 0.0011 19.3 0.0 5.5 5 1 1 6 6 6 2 Ankyrin repeat EnY2 PF10163.9 EAN34022.1 - 0.32 11.4 1.8 4.9 7.6 0.1 3.1 2 1 0 2 2 2 0 Transcription factor e(y)2 Ntox28 PF15605.6 EAN34022.1 - 0.7 10.2 3.5 1.2 9.4 0.6 2.6 2 0 0 2 2 2 0 Bacterial toxin 28 PMM PF03332.13 EAN34023.1 - 4.8e-84 281.5 3.5 3.1e-82 275.6 3.5 2.0 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EAN34023.1 - 8.5e-12 45.3 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAN34023.1 - 0.0051 16.4 0.0 0.29 10.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Yip1 PF04893.17 EAN34024.1 - 0.00038 20.2 17.2 0.00057 19.6 17.2 1.3 1 0 0 1 1 1 1 Yip1 domain Gcd10p PF04189.13 EAN34025.1 - 4.7e-29 101.5 6.8 5.9e-20 71.6 3.5 2.0 1 1 1 2 2 2 2 Gcd10p family SurA_N_3 PF13624.6 EAN34025.1 - 0.0015 18.4 1.2 0.0021 17.9 1.2 1.3 1 1 0 1 1 1 1 SurA N-terminal domain DUF3475 PF11961.8 EAN34025.1 - 0.063 13.4 0.1 0.16 12.1 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3475) Ribosomal_L11 PF00298.19 EAN34026.1 - 2.2e-21 76.2 0.2 4.2e-21 75.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EAN34026.1 - 3.1e-21 75.0 0.0 6.3e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Actin PF00022.19 EAN34027.1 - 7.3e-81 271.8 0.0 9.2e-80 268.2 0.0 1.9 1 1 0 1 1 1 1 Actin Es2 PF09751.9 EAN34028.1 - 4.2e-19 69.6 16.5 8.6e-09 35.6 0.2 3.4 2 1 0 2 2 2 2 Nuclear protein Es2 Methyltr_RsmB-F PF01189.17 EAN34029.1 - 1.1e-31 110.0 0.2 3.2e-26 92.2 0.0 2.2 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 EAN34029.1 - 0.023 14.5 0.1 0.054 13.3 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 EAN34029.1 - 0.043 13.9 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase E1_UFD PF09358.10 EAN34029.1 - 0.36 11.6 1.5 4 8.2 0.0 2.9 3 1 0 3 3 3 0 Ubiquitin fold domain Vps35 PF03635.17 EAN34032.1 - 3.4e-179 597.8 21.3 3.9e-179 597.6 21.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 YMF19 PF02326.15 EAN34034.1 - 0.046 14.5 0.7 0.057 14.2 0.2 1.4 2 0 0 2 2 2 0 Plant ATP synthase F0 TspO_MBR PF03073.15 EAN34034.1 - 0.16 12.1 0.0 0.16 12.0 0.0 1.0 1 0 0 1 1 1 0 TspO/MBR family PRP1_N PF06424.12 EAN34035.1 - 9.5e-32 110.4 13.3 9.5e-32 110.4 13.3 3.4 2 1 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EAN34035.1 - 1.1e-25 88.1 11.5 0.0028 18.3 0.0 13.5 9 4 6 15 15 15 4 Tetratricopeptide repeat TPR_19 PF14559.6 EAN34035.1 - 6e-24 84.3 9.1 0.00036 21.0 0.1 10.0 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EAN34035.1 - 5.7e-07 30.1 0.3 0.058 14.1 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAN34035.1 - 2e-05 24.4 24.3 0.045 13.9 0.4 10.2 11 1 0 11 11 11 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAN34035.1 - 4.2e-05 23.1 1.9 1.7 8.4 0.0 6.4 7 0 0 7 7 6 1 TPR repeat NRDE-2 PF08424.10 EAN34035.1 - 0.00018 20.8 25.0 0.02 14.0 1.0 5.3 1 1 3 5 5 5 2 NRDE-2, necessary for RNA interference TPR_1 PF00515.28 EAN34035.1 - 0.00035 20.3 8.8 0.013 15.3 0.5 5.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAN34035.1 - 0.00053 20.2 2.0 33 5.2 0.0 7.7 9 1 0 10 10 9 0 Tetratricopeptide repeat TPR_21 PF09976.9 EAN34035.1 - 0.00071 19.3 8.8 0.44 10.2 0.2 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 EAN34035.1 - 0.0015 18.6 17.3 0.71 10.2 0.0 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 EAN34035.1 - 0.0017 17.6 16.4 1 8.5 0.5 5.6 4 2 1 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAN34035.1 - 0.0061 16.8 11.0 0.13 12.5 0.6 4.9 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 EAN34035.1 - 0.0094 15.7 11.8 2.2 8.0 0.1 4.8 2 1 2 4 4 4 2 26S proteasome subunit RPN7 TPR_10 PF13374.6 EAN34035.1 - 0.037 13.9 2.2 10 6.2 0.2 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAN34035.1 - 0.042 14.2 15.6 0.21 11.9 0.1 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAN34035.1 - 0.16 12.0 0.1 0.16 12.0 0.1 4.1 4 1 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat EntA_Immun PF08951.10 EAN34035.1 - 5.1 7.5 17.0 4.5 7.7 0.3 5.2 5 0 0 5 5 5 0 Enterocin A Immunity zf-Tim10_DDP PF02953.15 EAN34037.1 - 6.6e-19 67.3 2.6 8.7e-19 66.9 2.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FAST_1 PF06743.15 EAN34038.1 - 0.0017 18.3 20.9 0.15 12.0 0.7 6.7 5 2 1 6 6 6 3 FAST kinase-like protein, subdomain 1 MRP-S26 PF14943.6 EAN34038.1 - 0.064 13.2 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Asp PF00026.23 EAN34040.1 - 5.6e-13 49.0 0.1 8.6e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAN34040.1 - 0.044 14.0 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Asp PF00026.23 EAN34041.1 - 2.9e-05 23.7 0.1 5.8e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease ERCC4 PF02732.15 EAN34041.1 - 0.018 15.3 0.1 0.023 14.9 0.1 1.3 1 0 0 1 1 1 0 ERCC4 domain SNO PF01174.19 EAN34041.1 - 0.032 14.1 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family UQ_con PF00179.26 EAN34042.1 - 3.9e-37 127.0 0.0 4.8e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAN34042.1 - 0.049 13.3 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B SNF2_N PF00176.23 EAN34043.1 - 3.5e-52 177.3 0.0 6.3e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAN34043.1 - 6.7e-16 58.6 0.0 2.7e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN34043.1 - 1.6e-09 38.0 0.0 1e-08 35.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EAN34043.1 - 5.6e-06 25.7 0.0 3.6e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EAN34043.1 - 0.0002 21.2 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EAN34043.1 - 0.01 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 EAN34043.1 - 0.017 14.4 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EAN34043.1 - 0.021 15.1 0.0 0.084 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.7 EAN34043.1 - 0.031 14.2 0.0 0.083 12.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like DIE2_ALG10 PF04922.12 EAN34043.1 - 0.2 10.9 0.2 0.42 9.8 0.0 1.5 2 0 0 2 2 2 0 DIE2/ALG10 family DBI_PRT PF02277.17 EAN34043.1 - 0.25 10.5 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase LSM PF01423.22 EAN34044.1 - 2.1e-21 75.3 0.1 2.4e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAN34044.1 - 0.024 14.8 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Ufd2P_core PF10408.9 EAN34046.1 - 7.2e-139 464.3 19.2 1e-138 463.7 19.2 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EAN34046.1 - 2e-24 85.6 1.3 6.5e-24 83.9 1.3 1.9 1 0 0 1 1 1 1 U-box domain BRE1 PF08647.11 EAN34046.1 - 0.029 14.4 0.3 0.12 12.4 0.3 2.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Qua1 PF16274.5 EAN34046.1 - 0.035 13.9 0.2 0.2 11.5 0.1 2.5 2 0 0 2 2 2 0 Qua1 domain RNA_pol_Rpb1_5 PF04998.17 EAN34047.1 - 9.4e-88 294.1 0.0 2.9e-87 292.5 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EAN34047.1 - 2.2e-62 210.2 0.1 5.2e-62 209.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EAN34047.1 - 2.3e-30 105.6 0.0 6.6e-30 104.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EAN34047.1 - 1.8e-20 73.5 12.3 1e-19 71.1 6.0 2.7 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EAN34047.1 - 4.1e-14 52.4 4.1 6.7e-14 51.7 0.2 3.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 ECSCR PF15820.5 EAN34047.1 - 0.13 12.1 0.2 0.34 10.8 0.2 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator ArfGap PF01412.18 EAN34048.1 - 4.6e-30 104.1 0.0 4.6e-30 104.1 0.0 2.0 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf CoaE PF01121.20 EAN34049.1 - 1.4e-31 109.5 0.0 1.8e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase DUF2701 PF10857.8 EAN34049.1 - 2.7 8.1 6.4 0.54 10.3 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2701) zf-CCCH PF00642.24 EAN34050.1 - 1.6e-09 37.4 2.7 3.3e-09 36.4 2.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 EAN34050.1 - 8.2e-07 28.9 9.5 8.2e-07 28.9 9.5 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAN34050.1 - 5.6e-06 26.3 4.8 1.5e-05 24.9 4.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 EAN34050.1 - 1.2e-05 25.2 4.4 3e-05 23.9 4.4 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 EAN34050.1 - 4.3e-05 23.6 9.2 5.3e-05 23.3 7.4 2.1 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 EAN34050.1 - 0.0001 22.1 11.8 0.00028 20.7 11.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAN34050.1 - 0.00011 21.9 9.4 0.00029 20.6 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAN34050.1 - 0.00085 19.1 6.0 0.00085 19.1 6.0 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EAN34050.1 - 0.0021 17.9 12.9 0.0021 17.9 12.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAN34050.1 - 0.0022 18.3 11.9 0.0084 16.4 11.9 2.0 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EAN34050.1 - 0.0024 18.1 8.8 0.0079 16.5 8.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-CCCH_4 PF18044.1 EAN34050.1 - 0.0037 17.0 2.8 0.0037 17.0 2.8 2.0 2 0 0 2 2 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 EAN34050.1 - 0.031 14.4 12.4 0.11 12.6 10.7 2.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 EAN34050.1 - 0.47 10.1 10.6 1.3 8.8 10.6 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 EAN34050.1 - 0.86 9.4 15.7 0.43 10.4 11.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DNA_pol_phi PF04931.13 EAN34050.1 - 3.3 5.7 15.0 5.2 5.0 15.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF1168 PF06658.12 EAN34050.1 - 7.4 6.4 16.4 0.27 11.0 9.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) TIP49 PF06068.13 EAN34051.1 - 0.028 13.6 0.8 0.038 13.2 0.1 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain DUF2951 PF11166.8 EAN34051.1 - 2.3 8.5 6.2 1.2 9.4 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) zf-CCCH_4 PF18044.1 EAN34052.1 - 1.1e-05 25.0 11.7 0.0041 16.9 0.1 4.6 4 0 0 4 4 4 2 CCCH-type zinc finger zf-CCCH PF00642.24 EAN34052.1 - 0.0016 18.3 1.6 0.0016 18.3 1.6 5.5 6 0 0 6 6 6 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAN34052.1 - 0.0031 17.5 0.6 0.0031 17.5 0.6 5.1 5 0 0 5 5 5 2 Zinc finger domain EKAL PF17986.1 EAN34052.1 - 0.082 13.0 1.4 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 EMP3-KAHRP-like N-terminal domain Pro_isomerase PF00160.21 EAN34053.1 - 6.2e-48 163.0 0.2 1.3e-47 162.0 0.2 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EAN34053.1 - 1.7e-06 28.6 0.6 0.18 12.7 0.1 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EAN34053.1 - 0.0012 17.9 0.0 0.11 11.4 0.0 2.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EAN34053.1 - 0.052 13.8 0.1 0.68 10.3 0.0 2.8 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Thioredoxin_3 PF13192.6 EAN34053.1 - 0.11 12.6 0.1 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin domain 5_3_exonuc PF01367.20 EAN34054.1 - 0.016 15.8 0.1 0.053 14.1 0.1 1.9 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TauE PF01925.19 EAN34055.1 - 1.6e-23 83.6 3.0 5.6e-14 52.3 0.2 2.2 1 1 0 2 2 2 2 Sulfite exporter TauE/SafE DUF2207 PF09972.9 EAN34055.1 - 4 6.1 8.0 1.5 7.5 0.4 2.9 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) tRNA-synt_2 PF00152.20 EAN34056.1 - 1.1e-66 225.1 0.1 1.6e-66 224.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAN34056.1 - 2.9e-08 33.6 0.0 6.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.7 EAN34056.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 tRNA_anti-like tRNA-synt_2d PF01409.20 EAN34056.1 - 0.034 13.6 0.0 0.76 9.2 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Phage_T7_tail PF03906.14 EAN34056.1 - 0.035 13.8 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Phage T7 tail fibre protein PI3_PI4_kinase PF00454.27 EAN34058.1 - 1.6e-30 106.7 0.1 6.3e-23 81.9 0.1 2.9 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EAN34058.1 - 9.4e-12 44.7 0.5 6.6e-10 38.7 0.3 2.4 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Nse4_C PF08743.10 EAN34059.1 - 1.2e-05 25.4 0.1 0.00016 21.9 0.0 2.4 2 0 0 2 2 2 1 Nse4 C-terminal DEAD PF00270.29 EAN34060.1 - 6.4e-42 143.3 0.1 1.2e-41 142.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN34060.1 - 3e-24 85.5 4.8 1.4e-22 80.1 1.1 3.7 3 1 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EAN34060.1 - 6.5e-11 42.3 0.0 1.6e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EAN34060.1 - 5.8e-05 23.1 0.1 0.00018 21.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EAN34060.1 - 0.017 14.9 0.1 0.017 14.9 0.1 2.6 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EAN34060.1 - 0.049 14.0 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain OHCU_decarbox PF09349.10 EAN34061.1 - 0.33 11.4 7.1 2.1 8.8 5.6 2.6 2 1 1 3 3 3 0 OHCU decarboxylase Calsarcin PF05556.11 EAN34061.1 - 0.4 10.2 16.7 6.1e+02 -0.2 16.6 3.9 1 1 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) Pkinase PF00069.25 EAN34062.1 - 3.2e-10 39.8 1.5 1.6e-05 24.4 0.6 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAN34062.1 - 6e-08 32.3 0.5 1.2e-05 24.8 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAN34062.1 - 0.0015 17.9 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RabGAP-TBC PF00566.18 EAN34062.1 - 0.041 13.5 8.1 0.019 14.6 4.1 2.6 2 1 0 2 2 2 0 Rab-GTPase-TBC domain Rhodanese PF00581.20 EAN34063.1 - 2.1e-05 25.0 0.0 5.4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain RRM_1 PF00076.22 EAN34064.1 - 4.1e-10 39.3 0.1 4.9e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EAN34064.1 - 0.00069 19.8 0.5 0.0048 17.1 0.1 2.1 1 1 1 2 2 2 1 BRCA1-associated protein 2 RFC1 PF08519.12 EAN34064.1 - 0.16 12.1 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain SRP9-21 PF05486.12 EAN34065.1 - 1.1e-05 25.8 0.5 0.00097 19.5 0.5 2.3 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) NMD3 PF04981.13 EAN34066.1 - 4.8e-63 212.9 14.4 4.8e-63 212.9 14.4 1.6 2 0 0 2 2 2 1 NMD3 family RRT14 PF17075.5 EAN34066.1 - 0.0092 16.1 7.7 0.0092 16.1 7.7 2.1 2 0 0 2 2 2 1 Regular of rDNA transcription protein 14 DZR PF12773.7 EAN34066.1 - 0.034 14.2 2.2 0.034 14.2 2.2 2.7 3 0 0 3 3 3 0 Double zinc ribbon Brix PF04427.18 EAN34067.1 - 1e-31 110.6 0.2 1.6e-31 109.9 0.2 1.2 1 0 0 1 1 1 1 Brix domain FtsJ PF01728.19 EAN34068.1 - 1.2e-56 191.6 0.0 1.7e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Adaptin_N PF01602.20 EAN34070.1 - 3.7e-61 207.3 10.8 4.5e-61 207.0 10.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAN34070.1 - 6.9e-24 84.7 11.6 8.1e-24 84.5 1.0 3.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAN34070.1 - 0.0028 18.0 0.0 0.12 12.7 0.0 3.1 3 0 0 3 3 3 1 HEAT repeats API5 PF05918.11 EAN34070.1 - 0.068 12.0 0.2 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) HEAT PF02985.22 EAN34070.1 - 0.07 13.4 0.1 6.2 7.4 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat DUF3713 PF12506.8 EAN34070.1 - 0.077 13.3 0.3 0.23 11.7 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) MT PF12777.7 EAN34072.1 - 6.9e-23 81.2 13.0 6.9e-23 81.2 13.0 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EAN34072.1 - 4e-11 43.0 0.3 2.1e-10 40.7 0.3 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EAN34072.1 - 4.3e-10 39.7 0.1 1.7e-09 37.8 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Jnk-SapK_ap_N PF09744.9 EAN34072.1 - 0.011 15.9 8.9 0.011 15.9 8.9 3.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FOXP-CC PF16159.5 EAN34072.1 - 0.47 11.1 2.6 9.2 7.0 0.1 3.0 2 0 0 2 2 2 0 FOXP coiled-coil domain Spc7 PF08317.11 EAN34072.1 - 1.5 7.6 36.4 0.006 15.5 12.3 3.6 4 0 0 4 4 4 0 Spc7 kinetochore protein SlyX PF04102.12 EAN34072.1 - 3.4 8.4 13.3 8.8 7.0 3.7 3.8 3 0 0 3 3 3 0 SlyX OmpH PF03938.14 EAN34072.1 - 4.7 7.6 20.0 0.79 10.1 7.1 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) AAA_6 PF12774.7 EAN34073.1 - 9.9e-58 195.6 0.2 3e-57 194.1 0.2 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EAN34073.1 - 7.5e-22 78.0 2.4 7.5e-22 78.0 2.4 2.9 2 1 0 2 2 1 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 EAN34073.1 - 3.8e-11 43.1 0.0 5.3e-05 23.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EAN34073.1 - 1.9e-06 27.5 1.6 0.1 12.1 0.1 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_22 PF13401.6 EAN34073.1 - 3.5e-06 27.3 0.0 0.077 13.3 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 EAN34073.1 - 0.00015 22.2 0.2 0.34 11.3 0.0 5.0 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAN34073.1 - 0.00082 19.8 0.0 0.61 10.4 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 EAN34073.1 - 0.0022 18.4 0.1 2.7 8.4 0.0 4.4 3 0 0 3 3 3 1 RNA helicase DUF959 PF06121.14 EAN34073.1 - 0.018 15.3 0.1 0.029 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) ABC_tran PF00005.27 EAN34073.1 - 0.033 14.7 0.7 1.3 9.5 0.0 3.5 3 0 0 3 3 3 0 ABC transporter AAA_30 PF13604.6 EAN34073.1 - 0.043 13.5 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain SPX PF03105.19 EAN34073.1 - 0.072 13.0 5.2 0.12 12.3 5.2 1.3 1 0 0 1 1 1 0 SPX domain Zeta_toxin PF06414.12 EAN34073.1 - 0.08 12.2 0.0 0.99 8.6 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin DUF1643 PF07799.12 EAN34073.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) FtsK_SpoIIIE PF01580.18 EAN34073.1 - 0.13 11.6 0.1 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF4351 PF14261.6 EAN34073.1 - 0.14 12.3 0.1 0.63 10.1 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4351) AAA_29 PF13555.6 EAN34073.1 - 0.29 10.9 1.4 12 5.7 0.1 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain Prok-RING_4 PF14447.6 EAN34074.1 - 3e-05 23.8 4.5 7.1e-05 22.6 4.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EAN34074.1 - 3.2e-05 23.8 2.5 0.0001 22.3 2.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAN34074.1 - 4.2e-05 23.4 4.3 0.00011 22.1 4.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EAN34074.1 - 0.00013 22.1 1.7 0.00031 20.8 1.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EAN34074.1 - 0.00056 19.7 4.2 0.0011 18.8 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAN34074.1 - 0.0038 17.5 4.7 0.01 16.2 4.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAN34074.1 - 0.016 15.0 5.7 0.046 13.6 5.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAN34074.1 - 0.068 13.0 5.1 0.2 11.5 5.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EAN34074.1 - 0.1 12.8 3.1 0.26 11.5 3.1 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EAN34074.1 - 0.21 11.4 3.5 0.38 10.6 2.4 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DASH_Spc19 PF08287.11 EAN34074.1 - 2.8 7.8 7.9 0.092 12.6 0.8 2.1 2 0 0 2 2 2 0 Spc19 Flavodoxin_1 PF00258.25 EAN34076.1 - 1.4e-18 67.4 0.0 2.4e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 EAN34076.1 - 4.9e-14 52.4 0.0 6.9e-13 48.7 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Ole-e-6 PF09253.10 EAN34077.1 - 0.095 12.7 3.2 0.41 10.6 0.2 2.4 2 0 0 2 2 2 0 Pollen allergen ole e 6 PepSY_like PF11396.8 EAN34078.1 - 4.2 8.0 5.7 0.99 10.0 0.3 2.8 3 0 0 3 3 3 0 Putative beta-lactamase-inhibitor-like, PepSY-like tRNA_int_endo PF01974.17 EAN34079.1 - 1.4e-16 60.3 0.0 1.7e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain XRN_N PF03159.18 EAN34080.1 - 2.5e-60 203.9 0.1 3.9e-60 203.3 0.1 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EAN34080.1 - 5.5e-26 91.5 9.8 1e-15 57.7 0.5 3.2 2 1 1 3 3 3 3 Xrn1 helical domain Sterile PF03015.19 EAN34080.1 - 0.01 16.1 2.0 0.022 15.0 1.0 2.1 1 1 1 2 2 2 1 Male sterility protein Nup54 PF13874.6 EAN34081.1 - 0.022 14.9 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 UQ_con PF00179.26 EAN34082.1 - 2.4e-25 88.8 0.1 3.3e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EAN34082.1 - 0.0027 17.6 0.2 0.006 16.4 0.1 1.6 2 0 0 2 2 2 1 UEV domain RWD PF05773.22 EAN34082.1 - 0.011 16.1 0.4 0.015 15.6 0.3 1.4 1 1 0 1 1 1 0 RWD domain AAA PF00004.29 EAN34083.1 - 1.4e-43 148.5 0.3 3.7e-43 147.1 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EAN34083.1 - 5.2e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EAN34083.1 - 2.5e-10 40.0 0.4 5e-10 39.0 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EAN34083.1 - 1.9e-06 28.1 0.0 4.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EAN34083.1 - 2.8e-06 27.7 0.2 0.0094 16.2 0.1 2.7 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 EAN34083.1 - 1.6e-05 24.9 0.3 0.00013 22.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EAN34083.1 - 2.1e-05 24.3 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EAN34083.1 - 2.8e-05 24.2 0.1 0.01 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EAN34083.1 - 3e-05 23.3 0.0 6.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EAN34083.1 - 5.3e-05 23.7 0.1 0.00089 19.7 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EAN34083.1 - 0.0016 18.2 0.0 0.005 16.6 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein NTPase_1 PF03266.15 EAN34083.1 - 0.0021 18.0 1.2 0.25 11.2 0.0 3.0 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.22 EAN34083.1 - 0.0042 17.5 0.0 0.0095 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EAN34083.1 - 0.0045 17.5 0.0 0.009 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EAN34083.1 - 0.0045 16.2 0.0 0.0095 15.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EAN34083.1 - 0.0049 17.0 0.0 0.0088 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cas_St_Csn2 PF16813.5 EAN34083.1 - 0.0072 15.5 0.2 0.012 14.7 0.2 1.2 1 0 0 1 1 1 1 CRISPR-associated protein Csn2 subfamily St AAA_28 PF13521.6 EAN34083.1 - 0.0077 16.5 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EAN34083.1 - 0.014 14.8 0.1 0.03 13.7 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EAN34083.1 - 0.016 14.6 0.2 0.11 11.9 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 EAN34083.1 - 0.018 15.0 0.1 0.44 10.5 0.0 2.7 2 1 1 3 3 3 0 NACHT domain AAA_24 PF13479.6 EAN34083.1 - 0.026 14.2 1.4 0.11 12.2 1.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EAN34083.1 - 0.029 14.2 0.0 0.098 12.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EAN34083.1 - 0.043 13.7 0.8 1.7 8.5 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EAN34083.1 - 0.047 13.2 0.0 0.13 11.7 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 EAN34083.1 - 0.073 13.5 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EAN34083.1 - 0.08 12.1 0.1 0.41 9.8 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 EAN34083.1 - 0.096 12.4 0.1 0.74 9.5 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 EAN34083.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EAN34083.1 - 0.11 12.2 0.2 0.26 11.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EAN34083.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 EAN34083.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 EAN34083.1 - 0.15 12.5 0.1 0.33 11.5 0.1 1.9 1 1 0 1 1 1 0 ABC transporter Syntaxin-6_N PF09177.11 EAN34084.1 - 2.7e-14 53.5 5.9 5.1e-14 52.6 0.1 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal ArsR PF09824.9 EAN34084.1 - 0.031 13.9 4.8 0.19 11.3 1.4 2.3 1 1 1 2 2 2 0 ArsR transcriptional regulator Fez1 PF06818.15 EAN34084.1 - 0.046 14.2 9.1 0.018 15.5 6.1 1.6 1 1 1 2 2 2 0 Fez1 Exonuc_VII_L PF02601.15 EAN34084.1 - 0.27 10.7 7.9 0.37 10.3 7.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cortex-I_coil PF09304.10 EAN34084.1 - 0.41 10.9 5.4 1.3 9.3 0.4 2.8 1 1 1 2 2 2 0 Cortexillin I, coiled coil DHR10 PF18595.1 EAN34084.1 - 0.77 9.8 15.2 1 9.5 0.2 3.6 2 2 1 3 3 3 0 Designed helical repeat protein 10 domain FAD-SLDH PF12318.8 EAN34086.1 - 0.085 12.9 2.7 1.8 8.6 0.1 3.6 2 2 3 5 5 5 0 Membrane bound FAD containing D-sorbitol dehydrogenase mTERF PF02536.14 EAN34087.1 - 1.2e-19 70.4 2.9 1.6e-19 70.0 0.4 2.2 2 0 0 2 2 2 1 mTERF IF3_N PF05198.16 EAN34087.1 - 9.1e-07 29.1 0.0 2.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 EAN34087.1 - 0.0072 16.3 0.3 0.039 13.9 0.3 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain XPG_N PF00752.17 EAN34088.1 - 0.00068 20.1 0.1 0.0019 18.6 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 EAN34088.1 - 0.0032 17.8 0.0 0.0072 16.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region KH_1 PF00013.29 EAN34089.1 - 5e-07 29.5 0.1 0.02 14.7 0.0 2.3 2 0 0 2 2 2 2 KH domain RIH_assoc PF08454.11 EAN34089.1 - 0.02 14.8 0.2 0.042 13.7 0.2 1.5 1 0 0 1 1 1 0 RyR and IP3R Homology associated KH_2 PF07650.17 EAN34089.1 - 0.066 13.0 0.2 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 KH domain SRP54 PF00448.22 EAN34090.1 - 3e-77 258.7 0.0 5.6e-77 257.8 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EAN34090.1 - 1.7e-28 99.1 0.5 1.7e-28 99.1 0.5 2.9 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 EAN34090.1 - 2.4e-18 66.1 3.2 7.4e-18 64.5 3.2 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EAN34090.1 - 1.8e-05 24.4 0.0 6.6e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EAN34090.1 - 0.00012 21.1 0.0 0.00051 19.1 0.0 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EAN34090.1 - 0.00013 22.4 0.0 0.00033 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EAN34090.1 - 0.0015 18.7 0.0 0.004 17.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain Fe-ADH PF00465.19 EAN34090.1 - 0.0021 17.0 0.1 0.0044 15.9 0.0 1.6 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase CbiA PF01656.23 EAN34090.1 - 0.0075 16.3 0.0 0.018 15.1 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 EAN34090.1 - 0.0091 16.3 0.0 0.037 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EAN34090.1 - 0.0092 16.0 0.6 0.048 13.7 0.2 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit APS_kinase PF01583.20 EAN34090.1 - 0.011 15.6 0.2 0.053 13.4 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_30 PF13604.6 EAN34090.1 - 0.011 15.4 0.1 0.034 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EAN34090.1 - 0.013 14.9 0.9 0.093 12.1 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_17 PF13207.6 EAN34090.1 - 0.035 14.5 0.1 0.035 14.5 0.1 2.7 3 2 1 4 4 4 0 AAA domain VirE PF05272.11 EAN34090.1 - 0.039 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E PduV-EutP PF10662.9 EAN34090.1 - 0.052 13.3 0.3 7.2 6.4 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EAN34090.1 - 0.061 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Methyltransf_24 PF13578.6 EAN34090.1 - 0.072 14.1 0.0 0.17 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Zeta_toxin PF06414.12 EAN34090.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.14 EAN34090.1 - 0.089 12.7 0.1 0.41 10.6 0.0 2.2 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 EAN34090.1 - 0.14 12.1 1.4 2.2 8.1 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.6 EAN34090.1 - 0.18 11.4 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EAN34090.1 - 0.38 11.3 1.5 2.2 8.8 0.3 2.8 2 1 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 EAN34090.1 - 0.84 8.8 0.0 0.84 8.8 0.0 3.7 4 1 0 5 5 5 0 Anion-transporting ATPase EIF_2_alpha PF07541.12 EAN34091.1 - 1.2e-24 86.6 0.0 2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EAN34091.1 - 1.9e-10 40.9 0.2 4.5e-10 39.7 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EcKinase PF02958.20 EAN34091.1 - 0.029 13.7 0.2 0.075 12.3 0.0 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase EXOSC1 PF10447.9 EAN34091.1 - 0.085 13.5 0.2 0.27 11.9 0.1 2.0 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 DUF1059 PF06348.11 EAN34091.1 - 0.43 10.9 2.7 8.5 6.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) TPR_12 PF13424.6 EAN34092.1 - 5.7e-10 39.4 0.0 7.8e-09 35.7 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAN34092.1 - 0.00034 20.4 0.0 0.0027 17.5 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAN34092.1 - 0.0016 18.5 2.1 0.62 10.4 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Peptidase_Mx1 PF15890.5 EAN34092.1 - 0.056 12.9 1.3 0.069 12.6 1.3 1.1 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase G-patch PF01585.23 EAN34094.1 - 1.1e-12 47.6 1.7 2e-12 46.8 1.7 1.4 1 0 0 1 1 1 1 G-patch domain Phage_DsbA PF11126.8 EAN34094.1 - 0.0034 17.6 0.1 0.0079 16.4 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator DsbA KdgM PF06178.13 EAN34094.1 - 0.012 15.3 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) G-patch_2 PF12656.7 EAN34094.1 - 0.12 12.5 0.8 0.38 10.9 0.8 1.8 1 0 0 1 1 1 0 G-patch domain Gar1 PF04410.14 EAN34095.1 - 7.7e-18 64.7 0.5 1.9e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region TFIIS_C PF01096.18 EAN34096.1 - 8.8e-13 47.9 1.4 8.8e-13 47.9 1.4 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Ribosomal_L44 PF00935.19 EAN34096.1 - 0.0017 18.8 2.4 0.037 14.5 0.1 3.1 3 0 0 3 3 3 1 Ribosomal protein L44 Baculo_LEF5_C PF11792.8 EAN34096.1 - 0.0045 16.6 1.4 0.0045 16.6 1.4 2.1 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain HypA PF01155.19 EAN34096.1 - 0.016 15.2 1.7 1.2 9.1 0.3 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EAN34096.1 - 0.15 12.1 6.5 1.8 8.7 1.5 3.0 2 2 0 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 EAN34096.1 - 0.22 12.3 9.3 9.8 7.0 0.3 3.5 2 2 1 3 3 3 0 zinc-ribbon family PHD PF00628.29 EAN34096.1 - 0.38 10.7 8.8 1.1 9.2 1.4 2.9 3 0 0 3 3 3 0 PHD-finger PHD_4 PF16866.5 EAN34096.1 - 0.48 10.6 6.8 5 7.3 0.5 2.7 2 1 0 2 2 2 0 PHD-finger Stc1 PF12898.7 EAN34096.1 - 0.58 10.7 6.6 0.91 10.1 0.9 2.6 2 1 0 2 2 2 0 Stc1 domain RNA_POL_M_15KD PF02150.16 EAN34096.1 - 0.67 9.9 8.9 29 4.7 0.4 4.3 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit Zn-ribbon_8 PF09723.10 EAN34096.1 - 0.68 10.1 11.1 9.5 6.4 3.6 3.8 3 1 0 3 3 3 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 EAN34096.1 - 0.99 9.1 12.5 14 5.4 0.2 4.2 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit C1_4 PF07975.12 EAN34096.1 - 1.3 9.3 11.5 2.1 8.6 0.1 3.5 3 1 1 4 4 3 0 TFIIH C1-like domain zf-H2C2_2 PF13465.6 EAN34096.1 - 1.5 9.4 8.6 16 6.1 0.9 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Rpr2 PF04032.16 EAN34096.1 - 2.7 8.3 6.3 3.5 8.0 0.7 3.3 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2757 PF10955.8 EAN34096.1 - 3.5 8.0 8.2 42 4.5 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2757) zinc_ribbon_10 PF10058.9 EAN34096.1 - 4.2 7.2 7.7 9 6.1 0.1 3.6 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-DNL PF05180.12 EAN34096.1 - 5.3 7.1 9.9 0.22 11.5 2.7 2.3 3 0 0 3 3 3 0 DNL zinc finger DUF951 PF06107.11 EAN34096.1 - 5.7 6.9 6.4 52 3.9 0.2 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF951) Zn_Tnp_IS91 PF14319.6 EAN34096.1 - 6.4 6.9 7.8 4.3 7.4 3.1 2.9 3 1 0 3 3 3 0 Transposase zinc-binding domain PTH2 PF01981.16 EAN34097.1 - 7.6e-29 100.4 0.3 1.8e-17 63.7 0.0 2.1 1 1 1 2 2 2 2 Peptidyl-tRNA hydrolase PTH2 UCR_14kD PF02271.16 EAN34098.1 - 2.3e-17 62.8 0.0 3.4e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Hydrolase_3 PF08282.12 EAN34099.1 - 1.7e-36 126.3 0.0 2.2e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAN34099.1 - 0.00023 20.8 0.0 0.024 14.2 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EAN34099.1 - 0.014 15.7 0.0 0.016 15.5 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAN34099.1 - 0.063 13.4 0.2 0.16 12.1 0.2 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase GMP_synt_C PF00958.22 EAN34100.1 - 7.6e-32 109.2 1.1 1.3e-31 108.5 0.3 1.8 2 0 0 2 2 2 1 GMP synthase C terminal domain GATase PF00117.28 EAN34100.1 - 1.5e-17 64.0 0.0 2.6e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EAN34100.1 - 8.4e-08 31.6 0.0 1.5e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 NAD synthase PAPS_reduct PF01507.19 EAN34100.1 - 0.0017 18.4 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.16 EAN34100.1 - 0.0026 16.6 0.1 0.0045 15.8 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 EAN34100.1 - 0.062 12.9 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase ThiI PF02568.14 EAN34100.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 EAN34100.1 - 0.11 12.0 0.0 0.41 10.1 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Thioredoxin PF00085.20 EAN34101.1 - 3.9e-42 142.4 3.1 1.3e-28 99.0 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 EAN34101.1 - 4.9e-17 62.4 1.9 5.5e-09 36.2 0.0 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EAN34101.1 - 8.5e-08 31.9 0.8 0.00056 19.3 0.0 2.5 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EAN34101.1 - 1.6e-06 28.5 3.8 0.0097 16.3 0.1 4.6 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAN34101.1 - 2e-06 28.1 8.0 0.13 12.6 2.1 5.0 4 2 2 6 6 6 3 Thioredoxin-like TraF PF13728.6 EAN34101.1 - 1.6e-05 24.8 0.1 0.067 13.0 0.0 3.0 3 1 0 3 3 3 2 F plasmid transfer operon protein ERp29_N PF07912.13 EAN34101.1 - 4.1e-05 23.7 6.7 0.033 14.3 3.7 3.7 4 1 0 4 4 4 2 ERp29, N-terminal domain Thioredoxin_3 PF13192.6 EAN34101.1 - 0.00077 19.5 0.2 0.12 12.5 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.11 EAN34101.1 - 0.0074 16.2 0.0 1.8 8.6 0.0 2.8 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 EAN34101.1 - 0.011 15.4 1.2 5.9 6.5 0.0 3.5 2 2 0 3 3 3 0 Thioredoxin DUF2586 PF10758.9 EAN34101.1 - 0.019 14.2 0.1 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2586) Thioredoxin_7 PF13899.6 EAN34101.1 - 0.028 14.6 0.7 0.24 11.6 0.1 2.6 2 1 0 2 2 2 0 Thioredoxin-like CwfJ_C_1 PF04677.15 EAN34101.1 - 0.038 13.8 0.8 0.089 12.7 0.8 1.6 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Thioredoxin_4 PF13462.6 EAN34101.1 - 0.26 11.4 2.6 16 5.6 0.1 2.9 2 2 1 3 3 3 0 Thioredoxin zf-3CxxC PF13695.6 EAN34101.1 - 0.39 11.2 3.9 0.69 10.4 0.7 2.5 1 1 0 2 2 2 0 Zinc-binding domain RRM_1 PF00076.22 EAN34103.1 - 2.8e-32 110.4 0.0 1.1e-17 63.6 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAN34103.1 - 3.1e-05 23.9 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 EAN34103.1 - 0.00066 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EAN34103.1 - 0.0032 17.5 0.1 0.011 15.8 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 EAN34103.1 - 0.0085 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif SNF2_N PF00176.23 EAN34104.1 - 2.1e-59 201.0 0.2 2.1e-59 201.0 0.2 3.1 3 1 1 4 4 4 1 SNF2 family N-terminal domain Chromo PF00385.24 EAN34104.1 - 1.1e-24 86.0 4.6 1.5e-13 50.4 0.2 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EAN34104.1 - 5.2e-21 75.1 0.0 1.8e-20 73.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EAN34104.1 - 4.8e-11 42.4 0.2 1.4e-10 40.9 0.2 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EAN34104.1 - 2.3e-09 37.5 0.0 6.3e-08 32.8 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAN34104.1 - 9.2e-06 25.5 0.1 8.7e-05 22.4 0.0 2.7 2 1 1 3 3 3 1 DEAD/DEAH box helicase Tubulin PF00091.25 EAN34105.1 - 9.8e-43 146.6 0.4 1.8e-42 145.8 0.4 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain RnaseA PF00074.20 EAN34105.1 - 0.028 14.9 1.1 8.8 6.8 0.4 2.9 2 1 1 3 3 3 0 Pancreatic ribonuclease DUF1091 PF06477.13 EAN34105.1 - 0.038 14.5 0.4 0.038 14.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) DUF5412 PF17428.2 EAN34108.1 - 0.43 10.4 3.1 0.55 10.1 1.8 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5412) UBA PF00627.31 EAN34109.1 - 6.4e-23 80.3 6.8 3.6e-11 42.7 0.2 2.8 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 EAN34109.1 - 3.7e-18 65.0 11.6 8.8e-18 63.8 11.6 1.7 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 EAN34109.1 - 2.2e-13 49.7 0.8 3.8e-13 49.0 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EAN34109.1 - 1.1e-05 26.0 0.1 1.9e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAN34109.1 - 0.00018 21.8 0.2 0.00039 20.7 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 EAN34109.1 - 0.0042 16.9 1.5 0.0078 16.0 1.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EAN34109.1 - 0.0043 17.1 0.1 0.0081 16.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SOG2 PF10428.9 EAN34109.1 - 0.015 14.6 4.4 0.017 14.4 4.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TetR_C_11 PF16859.5 EAN34109.1 - 0.02 15.2 0.1 0.082 13.2 0.0 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1631 PF07793.11 EAN34109.1 - 0.044 12.2 1.9 0.056 11.9 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) SbcD_C PF12320.8 EAN34109.1 - 0.13 12.6 0.2 0.58 10.5 0.0 2.0 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Ubiquitin_4 PF18036.1 EAN34109.1 - 0.14 12.2 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain BCA_ABC_TP_C PF12399.8 EAN34109.1 - 0.3 11.0 0.8 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter CUE PF02845.16 EAN34109.1 - 4.5 7.1 8.4 3 7.7 0.1 4.0 4 0 0 4 4 4 0 CUE domain KH_1 PF00013.29 EAN34110.1 - 5.8e-09 35.7 0.0 2.1e-05 24.2 0.0 4.6 5 0 0 5 5 5 1 KH domain SLS PF14611.6 EAN34110.1 - 0.00057 19.8 0.2 0.00057 19.8 0.2 3.6 2 2 2 4 4 4 1 Mitochondrial inner-membrane-bound regulator DNA_pol3_beta_3 PF02768.15 EAN34110.1 - 0.34 10.8 4.3 21 5.0 0.0 4.1 5 0 0 5 5 5 0 DNA polymerase III beta subunit, C-terminal domain Proteasome PF00227.26 EAN34112.1 - 3.1e-46 157.3 0.1 3.9e-46 156.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit FAST_1 PF06743.15 EAN34113.1 - 0.17 11.8 11.6 1.9 8.5 1.8 4.3 4 2 1 5 5 5 0 FAST kinase-like protein, subdomain 1 Forkhead PF00250.18 EAN34113.1 - 0.18 12.1 1.8 0.54 10.6 0.0 2.6 2 1 1 3 3 3 0 Forkhead domain VirE2 PF07229.12 EAN34114.1 - 0.049 12.3 0.3 0.056 12.1 0.3 1.0 1 0 0 1 1 1 0 VirE2 Use1 PF09753.9 EAN34114.1 - 0.07 12.8 0.4 0.086 12.5 0.4 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 DotU PF09850.9 EAN34114.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system protein DotU DUF2207 PF09972.9 EAN34114.1 - 0.11 11.2 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) WEMBL PF05701.11 EAN34114.1 - 0.14 10.8 0.2 0.17 10.6 0.2 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Ras PF00071.22 EAN34115.1 - 2.4e-58 196.3 0.0 2.9e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAN34115.1 - 8.6e-34 116.3 0.0 1.2e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAN34115.1 - 5.2e-12 45.6 0.0 7.6e-12 45.0 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAN34115.1 - 3.8e-06 27.0 0.0 6.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAN34115.1 - 8.1e-05 22.2 0.0 0.00073 19.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAN34115.1 - 0.00025 20.5 0.0 0.00031 20.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAN34115.1 - 0.0064 16.4 0.1 0.79 9.6 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase DNA_pol_E_B PF04042.16 EAN34115.1 - 0.0066 15.8 0.0 0.0089 15.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B AAA_22 PF13401.6 EAN34115.1 - 0.025 14.8 0.0 0.049 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain YbbR PF07949.12 EAN34116.1 - 0.084 13.2 0.3 8.1 6.9 0.1 2.3 1 1 1 2 2 2 0 YbbR-like protein RRM_1 PF00076.22 EAN34117.1 - 8e-31 105.7 0.1 1e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAN34117.1 - 8e-10 38.7 0.2 0.00062 19.8 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif RL PF17797.1 EAN34117.1 - 0.00096 19.1 0.1 2.8 8.0 0.0 2.9 2 2 1 3 3 3 2 RL domain Nup35_RRM_2 PF14605.6 EAN34117.1 - 0.001 19.0 0.4 1.2 9.2 0.2 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EAN34117.1 - 0.0018 18.3 0.1 0.35 10.9 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif OB_RNB PF08206.11 EAN34117.1 - 0.088 12.5 0.0 9.4 6.0 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF1509 PF07420.11 EAN34117.1 - 5.1 5.9 11.5 6.9 5.5 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) RIO1 PF01163.22 EAN34118.1 - 4.2e-60 202.6 0.2 1.2e-59 201.1 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EAN34118.1 - 0.008 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EAN34118.1 - 0.08 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein tyrosine kinase CK_II_beta PF01214.18 EAN34119.1 - 1.1e-65 220.9 0.9 1.4e-65 220.6 0.9 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit UPF0228 PF05727.11 EAN34119.1 - 0.0076 16.1 1.0 0.0076 16.1 1.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0228) TRAP-delta PF05404.12 EAN34119.1 - 0.017 14.7 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) PBP1_TM PF14812.6 EAN34119.1 - 0.036 14.4 0.7 0.37 11.2 0.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal IBR PF01485.21 EAN34119.1 - 0.055 13.7 0.5 0.13 12.5 0.5 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ADK_lid PF05191.14 EAN34119.1 - 0.056 13.4 0.7 0.13 12.3 0.7 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid AAA_22 PF13401.6 EAN34120.1 - 0.0016 18.7 0.0 0.0048 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EAN34120.1 - 0.0048 16.7 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EAN34120.1 - 0.049 12.8 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 EAN34120.1 - 0.22 11.7 0.0 0.36 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAN34120.1 - 0.28 11.7 0.9 0.46 11.0 0.9 1.5 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.15 EAN34121.1 - 0.042 13.8 0.1 3.9 7.3 0.1 2.7 1 1 1 2 2 2 0 Rad17 P-loop domain DUF2046 PF09755.9 EAN34121.1 - 0.073 12.3 0.3 0.13 11.5 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) BTB PF00651.31 EAN34121.1 - 0.099 12.9 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 BTB/POZ domain eIF-5a PF01287.20 EAN34122.1 - 3e-26 91.3 0.3 4.3e-26 90.8 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EAN34122.1 - 2.9e-05 24.0 0.1 4.9e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Cu-oxidase PF00394.22 EAN34122.1 - 0.069 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Multicopper oxidase zf-Tim10_DDP PF02953.15 EAN34123.1 - 1e-12 47.5 0.2 1.2e-12 47.3 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cyto_heme_lyase PF01265.17 EAN34124.1 - 1.6e-35 123.1 1.7 1.2e-34 120.3 1.7 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF4925 PF16272.5 EAN34124.1 - 0.053 13.0 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4925) KH_1 PF00013.29 EAN34125.1 - 7.1e-05 22.6 0.5 0.00016 21.5 0.5 1.6 1 0 0 1 1 1 1 KH domain FlhE PF06366.13 EAN34125.1 - 0.087 12.8 0.0 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Flagellar protein FlhE Reticulon PF02453.17 EAN34126.1 - 4.3e-07 30.0 8.0 6.6e-07 29.4 8.0 1.3 1 0 0 1 1 1 1 Reticulon DUF639 PF04842.12 EAN34126.1 - 2 7.8 8.4 0.13 11.6 3.4 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Med7 PF05983.11 EAN34129.1 - 8.4e-12 45.6 1.1 1.1e-11 45.2 1.1 1.1 1 0 0 1 1 1 1 MED7 protein Ribosomal_L4 PF00573.22 EAN34130.1 - 1.7e-51 174.6 0.0 2.3e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Sec61_beta PF03911.16 EAN34131.1 - 0.0065 16.5 0.0 0.008 16.2 0.0 1.2 1 0 0 1 1 1 1 Sec61beta family CLP1_P PF16575.5 EAN34133.1 - 4.5e-23 82.0 0.2 1.3e-21 77.3 0.1 2.1 1 1 1 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EAN34133.1 - 4.7e-12 46.0 0.0 9.9e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CbiA PF01656.23 EAN34133.1 - 0.00073 19.6 0.0 0.0018 18.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain 5_3_exonuc_N PF02739.16 EAN34133.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain AAA_24 PF13479.6 EAN34133.1 - 0.06 13.1 0.0 0.2 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNase_PH PF01138.21 EAN34136.1 - 4.3e-05 24.0 0.0 5.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DNA_pol_B PF00136.21 EAN34137.1 - 1.3e-129 432.9 4.1 1.9e-129 432.4 4.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EAN34137.1 - 2.5e-69 234.0 7.2 2.5e-69 234.0 7.2 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EAN34137.1 - 6.8e-15 55.3 11.5 2.5e-14 53.5 11.5 2.1 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF1672 PF07901.11 EAN34137.1 - 0.06 12.7 0.5 0.43 9.9 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1672) Noc2 PF03715.13 EAN34138.1 - 2.5e-67 227.2 4.3 4.2e-67 226.5 4.3 1.4 1 0 0 1 1 1 1 Noc2p family SDA1 PF05285.12 EAN34138.1 - 4.5 6.6 19.1 2.8 7.3 15.7 2.0 2 0 0 2 2 2 0 SDA1 CwfJ_C_1 PF04677.15 EAN34139.1 - 3.1e-15 56.1 3.2 5.7e-14 52.0 3.2 2.3 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.22 EAN34139.1 - 3.1e-07 30.1 0.0 9.3e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CHCH PF06747.13 EAN34140.1 - 5e-05 23.3 0.4 5e-05 23.3 0.4 3.2 4 0 0 4 4 4 1 CHCH domain Syja_N PF02383.18 EAN34142.1 - 2.6e-62 211.0 0.1 6.6e-62 209.7 0.1 1.6 1 0 0 1 1 1 1 SacI homology domain Cyclin_N PF00134.23 EAN34143.1 - 0.0014 18.3 0.9 0.045 13.5 0.9 2.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain s48_45 PF07422.13 EAN34144.1 - 0.012 16.2 0.4 0.016 15.8 0.4 1.2 1 0 0 1 1 1 0 Sexual stage antigen s48/45 domain RNase_PH PF01138.21 EAN34145.1 - 0.00083 19.9 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Proteasome PF00227.26 EAN34146.1 - 1.2e-48 165.1 0.1 1.6e-48 164.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-RING_5 PF14634.6 EAN34147.1 - 0.00089 19.2 10.8 0.00089 19.2 10.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EAN34147.1 - 0.002 17.9 9.1 0.0041 17.0 9.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF1258 PF06869.12 EAN34147.1 - 0.002 17.6 1.5 0.0027 17.2 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) zf-C3HC4_2 PF13923.6 EAN34147.1 - 0.0021 17.8 7.8 0.0021 17.8 7.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN34147.1 - 0.0057 16.7 8.3 0.012 15.6 8.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger AAA_12 PF13087.6 EAN34147.1 - 0.011 15.4 0.5 0.078 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Lipase_GDSL_3 PF14606.6 EAN34147.1 - 0.013 15.6 0.1 0.018 15.2 0.1 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family zf_Hakai PF18408.1 EAN34147.1 - 0.014 15.1 0.1 0.014 15.1 0.1 1.8 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-C3HC4 PF00097.25 EAN34147.1 - 0.016 15.1 12.3 0.034 14.0 12.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAN34147.1 - 0.021 15.2 11.4 0.021 15.2 11.4 1.8 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 EAN34147.1 - 0.063 13.4 7.4 0.12 12.5 6.4 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 EAN34147.1 - 0.27 11.2 9.0 0.55 10.2 4.0 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BRCA-2_OB1 PF09103.10 EAN34148.1 - 0.05 13.6 0.0 1.5 8.7 0.0 2.9 1 1 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 NAD_binding_7 PF13241.6 EAN34148.1 - 0.15 12.5 0.0 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding DnaB_2 PF07261.11 EAN34150.1 - 0.033 13.9 0.2 0.056 13.2 0.1 1.6 1 1 0 1 1 1 0 Replication initiation and membrane attachment Aconitase PF00330.20 EAN34151.1 - 0.054 12.5 0.0 0.073 12.1 0.0 1.0 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) Rpr2 PF04032.16 EAN34154.1 - 2.7e-15 56.4 0.7 3.9e-15 55.9 0.7 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2935 PF11155.8 EAN34154.1 - 0.017 15.4 0.4 0.36 11.2 0.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) WD40 PF00400.32 EAN34156.1 - 3.6 8.6 8.7 0.98 10.4 0.6 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat YWFCY PF14293.6 EAN34157.1 - 4.1 7.8 8.2 8.4 6.8 0.7 3.3 2 0 0 2 2 2 0 YWFCY protein E1-E2_ATPase PF00122.20 EAN34160.1 - 9.6e-19 67.6 0.0 3.5e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EAN34160.1 - 9.4e-12 45.7 0.0 1.3e-07 32.1 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAN34160.1 - 7.2e-05 22.4 0.0 0.00024 20.7 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Ytp1 PF10355.9 EAN34160.1 - 0.0033 16.7 0.4 0.0065 15.7 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DEAD PF00270.29 EAN34161.1 - 5.7e-24 84.8 0.1 1.7e-23 83.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN34161.1 - 4.4e-19 68.9 1.5 8.8e-19 67.9 0.7 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN34161.1 - 1.3e-05 25.3 0.1 3.7e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YafO_toxin PF13957.6 EAN34161.1 - 0.065 13.3 0.2 0.14 12.3 0.2 1.4 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system AAA_14 PF13173.6 EAN34161.1 - 0.079 13.0 1.1 0.2 11.7 0.1 2.1 1 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EAN34161.1 - 0.15 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_L31e PF01198.19 EAN34162.1 - 4.1e-38 129.5 1.8 5.1e-38 129.2 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Cnd1 PF12717.7 EAN34163.1 - 2.6e-10 40.6 0.3 4.6e-07 30.0 0.0 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAN34163.1 - 1.6e-09 37.2 0.0 0.093 13.0 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat CLASP_N PF12348.8 EAN34163.1 - 0.00011 21.8 0.1 0.00033 20.3 0.0 1.7 1 1 1 2 2 2 2 CLASP N terminal Adaptin_N PF01602.20 EAN34163.1 - 0.00025 19.7 2.6 0.0094 14.6 0.0 2.9 1 1 2 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EAN34163.1 - 0.0035 17.9 0.6 0.66 10.6 0.1 3.8 3 1 2 5 5 5 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EAN34163.1 - 0.004 17.3 0.0 0.053 13.7 0.0 2.6 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 EAN34163.1 - 0.022 15.1 0.0 1.1 9.7 0.0 2.8 3 0 0 3 3 3 0 HEAT repeats DUF4042 PF13251.6 EAN34163.1 - 0.032 13.9 0.0 5.3 6.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 EAN34163.1 - 0.23 12.0 0.0 88 3.8 0.0 3.8 4 1 1 5 5 5 0 HEAT-like repeat Cofilin_ADF PF00241.20 EAN34164.1 - 4.5e-14 52.3 0.0 5.7e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Thymosin PF01290.20 EAN34164.1 - 0.022 14.5 0.6 0.022 14.5 0.6 1.6 2 0 0 2 2 2 0 Thymosin beta-4 family DUF348 PF03990.14 EAN34164.1 - 0.08 12.7 0.9 0.28 11.0 0.1 2.3 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain Prefoldin PF02996.17 EAN34165.1 - 5.5e-21 74.7 0.2 8.2e-21 74.1 0.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit APG17 PF04108.12 EAN34165.1 - 0.069 12.3 1.6 0.44 9.6 0.5 2.0 2 0 0 2 2 2 0 Autophagy protein Apg17 Tsi6 PF18660.1 EAN34165.1 - 0.099 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Tsi6 DUF4878 PF12870.7 EAN34165.1 - 0.14 12.5 2.4 0.44 10.9 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4878) Hrs_helical PF12210.8 EAN34165.1 - 0.19 12.3 1.6 0.2 12.2 0.4 1.6 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate KxDL PF10241.9 EAN34165.1 - 0.23 11.8 3.0 12 6.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein Osmo_CC PF08946.10 EAN34165.1 - 1.3 9.4 6.6 0.19 12.0 1.1 2.4 3 0 0 3 3 3 0 Osmosensory transporter coiled coil p25-alpha PF05517.12 EAN34166.1 - 2e-14 54.1 0.0 2.4e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 p25-alpha OSCP PF00213.18 EAN34167.1 - 6.4e-41 140.3 0.0 7.4e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PUB PF09409.10 EAN34167.1 - 0.12 12.3 0.7 0.49 10.4 0.0 2.4 3 0 0 3 3 3 0 PUB domain Myb_DNA-binding PF00249.31 EAN34168.1 - 0.00095 19.3 0.0 0.021 15.0 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain UIM PF02809.20 EAN34168.1 - 0.69 10.0 2.1 2 8.5 2.1 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif FAM222A PF15258.6 EAN34168.1 - 1.1 8.3 19.7 0.014 14.6 10.5 2.2 3 0 0 3 3 3 0 Protein family of FAM222A ATP_synt_H PF05493.13 EAN34170.1 - 0.27 11.7 1.5 0.42 11.1 0.5 1.8 2 0 0 2 2 2 0 ATP synthase subunit H TRAPPC-Trs85 PF12739.7 EAN34171.1 - 0.00013 21.1 1.0 0.00052 19.1 0.0 2.1 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit HSP90 PF00183.18 EAN34172.1 - 5.3e-117 391.9 70.8 4.8e-112 375.5 42.2 5.5 1 1 3 4 4 4 3 Hsp90 protein HATPase_c_3 PF13589.6 EAN34172.1 - 2.6e-08 33.8 0.0 2.6e-08 33.8 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EAN34172.1 - 2.4e-07 31.2 0.0 5.2e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF913 PF06025.12 EAN34172.1 - 0.0017 17.4 1.9 0.0017 17.4 1.9 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) Fumble PF03630.14 EAN34173.1 - 8e-14 51.6 0.1 2.4e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 Fumble SNF2_N PF00176.23 EAN34174.1 - 2.3e-62 210.7 0.0 8e-62 209.0 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 EAN34174.1 - 4.3e-28 97.6 1.0 1.3e-27 96.1 1.0 1.9 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.31 EAN34174.1 - 1.2e-17 64.3 0.1 6.4e-17 61.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAN34174.1 - 1.8e-08 34.6 0.3 1.3e-07 31.7 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRR1 PF07985.12 EAN34174.1 - 3.4e-05 23.8 0.1 9.1e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 SRR1 DEAD PF00270.29 EAN34174.1 - 0.0053 16.5 0.0 0.025 14.3 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EAN34174.1 - 0.0093 15.7 0.0 0.066 12.9 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_14 PF13173.6 EAN34174.1 - 0.078 13.0 0.7 0.35 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAN34175.1 - 1e-94 313.9 0.0 3.2e-46 157.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAN34175.1 - 3e-24 84.6 0.7 1.1e-10 41.1 0.0 2.9 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EAN34175.1 - 4.5e-20 71.6 0.1 1.2e-19 70.2 0.1 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EAN34175.1 - 3.5e-13 49.6 0.0 1.3e-05 25.0 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EAN34175.1 - 9.7e-13 48.9 0.3 0.00023 21.6 0.0 4.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EAN34175.1 - 2.1e-11 44.2 0.0 2.3e-06 27.8 0.0 3.0 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EAN34175.1 - 3.7e-11 43.4 0.1 2.6e-05 24.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 EAN34175.1 - 1.6e-10 41.1 0.1 1.6e-05 24.9 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAN34175.1 - 2e-08 34.6 0.3 0.028 14.7 0.0 3.9 2 2 1 3 3 2 2 AAA domain CDC48_2 PF02933.17 EAN34175.1 - 2.1e-08 33.8 0.0 4.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.13 EAN34175.1 - 4.2e-08 32.8 0.0 0.0012 18.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 EAN34175.1 - 1.2e-07 32.3 0.0 0.027 15.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EAN34175.1 - 4.3e-07 30.0 0.0 0.012 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EAN34175.1 - 7.8e-07 28.7 0.2 0.036 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EAN34175.1 - 9.8e-07 29.1 0.0 0.021 15.2 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 EAN34175.1 - 1.2e-06 28.2 0.3 0.79 9.3 0.0 4.0 3 1 0 4 4 4 2 AAA domain Vps4_C PF09336.10 EAN34175.1 - 8.2e-06 25.7 0.6 0.00056 19.9 0.0 3.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 EAN34175.1 - 1e-05 25.3 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 EAN34175.1 - 2.3e-05 24.4 0.0 0.79 9.6 0.0 3.4 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea NACHT PF05729.12 EAN34175.1 - 4.3e-05 23.5 0.0 0.53 10.2 0.0 3.8 4 1 1 5 5 3 2 NACHT domain ABC_tran PF00005.27 EAN34175.1 - 4.4e-05 24.0 0.0 0.33 11.5 0.0 3.5 2 1 0 2 2 2 2 ABC transporter ATPase PF06745.13 EAN34175.1 - 4.9e-05 22.8 0.1 2.4 7.5 0.0 3.3 3 0 0 3 3 3 1 KaiC AAA_28 PF13521.6 EAN34175.1 - 6.3e-05 23.3 0.0 0.33 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EAN34175.1 - 7.7e-05 22.3 0.0 0.36 10.3 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EAN34175.1 - 8.7e-05 22.4 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 EAN34175.1 - 8.8e-05 22.3 0.0 0.16 11.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EAN34175.1 - 0.0001 22.8 0.0 0.31 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EAN34175.1 - 0.00015 21.8 0.0 0.66 10.0 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 EAN34175.1 - 0.00024 20.3 0.0 0.46 9.5 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EAN34175.1 - 0.00047 19.9 0.0 1.1 9.0 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 EAN34175.1 - 0.00055 19.2 0.0 0.9 8.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.12 EAN34175.1 - 0.001 18.4 0.0 0.75 9.0 0.0 2.6 3 0 0 3 3 2 1 Zeta toxin Bac_DnaA PF00308.18 EAN34175.1 - 0.0012 18.7 0.0 0.58 9.9 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein DUF815 PF05673.13 EAN34175.1 - 0.002 17.3 0.0 0.57 9.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.16 EAN34175.1 - 0.0023 17.4 0.1 1.9 7.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 EAN34175.1 - 0.0033 16.7 0.0 0.72 9.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 EAN34175.1 - 0.0039 17.0 0.0 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EAN34175.1 - 0.0051 16.8 0.0 0.93 9.4 0.0 2.9 2 1 0 2 2 2 1 Rad17 P-loop domain ResIII PF04851.15 EAN34175.1 - 0.0057 16.7 0.0 0.33 10.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 EAN34175.1 - 0.0067 16.5 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 EAN34175.1 - 0.012 15.9 0.1 5.9 7.2 0.1 3.0 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EAN34175.1 - 0.018 15.0 0.7 7.6 6.4 0.0 3.7 4 0 0 4 4 3 0 NTPase SRPRB PF09439.10 EAN34175.1 - 0.023 14.2 0.0 39 3.6 0.0 3.4 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_30 PF13604.6 EAN34175.1 - 0.024 14.4 0.1 7.8 6.2 0.1 2.6 3 0 0 3 3 2 0 AAA domain Cytidylate_kin2 PF13189.6 EAN34175.1 - 0.029 14.5 0.0 15 5.7 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_11 PF13086.6 EAN34175.1 - 0.038 13.8 1.2 9.9 5.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 EAN34175.1 - 0.044 13.5 0.1 7.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_29 PF13555.6 EAN34175.1 - 0.047 13.4 0.0 5.9 6.7 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain SKI PF01202.22 EAN34175.1 - 0.058 13.5 0.1 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase eIF-1a PF01176.19 EAN34175.1 - 0.13 12.1 0.1 0.5 10.2 0.1 2.0 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 RMI1_N PF08585.12 EAN34175.1 - 0.14 11.9 0.2 0.28 10.9 0.2 1.4 1 0 0 1 1 1 0 RecQ mediated genome instability protein Hydin_ADK PF17213.3 EAN34175.1 - 1.7 8.9 3.8 65 3.7 0.1 3.5 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain F-box PF00646.33 EAN34176.1 - 0.028 14.3 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 F-box domain IES5 PF17335.2 EAN34177.1 - 0.028 14.7 1.2 0.028 14.7 1.2 2.1 2 1 0 2 2 2 0 Ino80 complex subunit 5 DUF5339 PF17274.2 EAN34177.1 - 0.091 13.6 3.4 0.26 12.1 0.7 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5339) 4HB_MCP_1 PF12729.7 EAN34177.1 - 0.14 11.7 14.0 0.061 12.9 3.0 2.5 1 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction NusB PF01029.18 EAN34177.1 - 0.27 11.5 2.6 1.2 9.3 0.1 2.6 2 1 0 2 2 2 0 NusB family SMC_ScpA PF02616.14 EAN34177.1 - 0.34 10.8 6.5 1.5 8.7 0.2 2.5 2 1 0 2 2 2 0 Segregation and condensation protein ScpA Syntaxin_2 PF14523.6 EAN34177.1 - 0.77 10.2 6.4 6.4 7.2 0.1 3.3 3 1 0 3 3 3 0 Syntaxin-like protein LSM PF01423.22 EAN34178.1 - 9.4e-12 44.5 0.0 1.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAN34178.1 - 0.13 12.4 0.0 0.3 11.3 0.0 1.6 2 0 0 2 2 2 0 Ataxin 2 SM domain GREB1 PF15782.5 EAN34179.1 - 5.9 3.9 15.0 7.7 3.5 15.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Choline_kinase PF01633.20 EAN34180.1 - 5.3e-47 160.2 0.0 9.1e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAN34180.1 - 3.5e-12 46.8 0.0 5.5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EAN34180.1 - 4.7e-05 22.9 0.1 9.6e-05 21.8 0.1 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 EAN34180.1 - 0.0027 17.1 2.6 0.79 9.0 0.1 2.8 2 1 0 2 2 2 2 Protein kinase domain DUF1679 PF07914.11 EAN34180.1 - 0.071 12.0 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 EAN34181.1 - 1.2e-50 172.4 0.0 1.7e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN34181.1 - 1.5e-34 119.5 0.0 2.2e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAN34181.1 - 0.00012 21.2 0.2 0.00012 21.2 0.2 1.4 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EAN34181.1 - 0.0017 17.2 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAN34181.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ku_C PF03730.14 EAN34182.1 - 0.021 15.5 0.4 0.072 13.8 0.1 2.1 1 1 0 1 1 1 0 Ku70/Ku80 C-terminal arm DUF3037 PF11236.8 EAN34182.1 - 0.028 14.8 0.4 0.074 13.5 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) ZapA PF05164.13 EAN34182.1 - 0.036 14.5 0.9 0.1 13.1 0.9 1.7 1 0 0 1 1 1 0 Cell division protein ZapA Sigma70_ner PF04546.13 EAN34182.1 - 0.086 12.7 6.0 0.17 11.7 6.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF885 PF05960.11 EAN34182.1 - 0.2 11.2 1.3 0.3 10.7 0.8 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) PCRF PF03462.18 EAN34182.1 - 0.32 10.8 3.2 0.61 9.9 3.2 1.5 1 0 0 1 1 1 0 PCRF domain DUF4363 PF14276.6 EAN34182.1 - 4 7.6 7.8 2.7 8.2 5.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) RRM_1 PF00076.22 EAN34183.1 - 2.8e-76 251.3 0.8 7.2e-21 73.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EAN34183.1 - 9.1e-28 96.2 0.3 1.9e-25 88.8 0.8 3.2 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 EAN34183.1 - 3.9e-07 30.0 0.6 0.56 10.2 0.0 4.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EAN34183.1 - 3.5e-05 23.8 0.2 3.1 7.9 0.1 4.0 3 1 0 4 4 4 2 RNA binding motif RRM_7 PF16367.5 EAN34183.1 - 9e-05 22.5 0.1 3.8 7.7 0.0 4.3 4 1 0 4 4 4 2 RNA recognition motif DUF4523 PF15023.6 EAN34183.1 - 0.00012 22.0 0.0 3.1 7.6 0.0 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF4523) RNA_bind PF08675.11 EAN34183.1 - 0.023 14.7 0.0 0.82 9.7 0.0 3.1 4 0 0 4 4 4 0 RNA binding domain Limkain-b1 PF11608.8 EAN34183.1 - 0.13 12.3 0.0 20 5.3 0.0 3.3 2 1 1 3 3 3 0 Limkain b1 RRS1 PF04939.12 EAN34184.1 - 3e-45 154.0 1.1 5.1e-45 153.3 1.1 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DUF4435 PF14491.6 EAN34184.1 - 0.042 13.7 1.7 0.061 13.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) DUF883 PF05957.13 EAN34184.1 - 0.043 14.4 1.3 0.07 13.7 1.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) GrpE PF01025.19 EAN34185.1 - 1.2e-43 148.6 13.8 5.1e-43 146.6 13.8 1.8 1 1 0 1 1 1 1 GrpE UPF0449 PF15136.6 EAN34185.1 - 0.27 11.7 7.1 0.56 10.7 7.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF4407 PF14362.6 EAN34185.1 - 0.55 9.5 3.1 0.81 9.0 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 EAN34185.1 - 2.9 8.5 10.5 3.1 8.4 8.7 2.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal LSM PF01423.22 EAN34187.1 - 5.6e-15 54.8 1.5 7.6e-15 54.4 1.5 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAN34187.1 - 0.056 13.6 0.2 0.074 13.2 0.2 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Tim44 PF04280.15 EAN34188.1 - 1.8e-33 115.7 0.0 3.6e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Tim44-like domain DUF3818 PF12825.7 EAN34188.1 - 0.032 13.2 3.0 0.043 12.8 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) STI1 PF17830.1 EAN34188.1 - 0.074 13.0 0.1 3.1 7.8 0.0 2.6 2 1 0 2 2 2 0 STI1 domain TBPIP PF07106.13 EAN34188.1 - 0.086 12.8 0.0 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain DUF2400 PF09674.10 EAN34188.1 - 0.087 12.8 4.7 0.038 14.0 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) SesA PF17107.5 EAN34188.1 - 0.39 10.9 4.2 1.7 8.8 4.2 2.0 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases LMBR1 PF04791.16 EAN34188.1 - 0.67 8.8 2.3 0.87 8.4 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Tim17 PF02466.19 EAN34189.1 - 1.2e-25 90.0 5.0 1.5e-25 89.7 5.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 EAN34189.1 - 0.018 15.1 4.1 0.35 11.0 0.2 2.4 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III ATP-synt_E_2 PF08112.11 EAN34189.1 - 0.091 13.0 0.1 0.51 10.7 0.2 2.0 2 0 0 2 2 2 0 ATP synthase epsilon subunit MMS19_N PF14500.6 EAN34190.1 - 1.1e-28 100.5 1.9 5.7e-28 98.2 0.5 2.6 2 1 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II PhyH PF05721.13 EAN34192.1 - 3e-06 27.6 0.0 7.4e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MOLO1 PF17175.4 EAN34193.1 - 2.8e-06 27.4 2.4 0.00017 21.7 0.1 2.6 2 1 1 3 3 3 2 Modulator of levamisole receptor-1 Transket_pyr PF02779.24 EAN34194.1 - 1.2e-40 139.0 0.1 2e-40 138.3 0.0 1.4 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EAN34194.1 - 1.3e-36 125.2 0.0 2.2e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EAN34194.1 - 0.0024 18.2 0.0 0.0048 17.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II tRNA-synt_2b PF00587.25 EAN34195.1 - 1.2e-31 110.1 0.0 2.3e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EAN34195.1 - 4.6e-19 68.4 0.0 2e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 EAN34195.1 - 9.4e-08 32.0 0.0 2.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Prenylcys_lyase PF07156.14 EAN34195.1 - 0.016 14.3 0.9 0.064 12.3 0.0 2.1 2 1 1 3 3 3 0 Prenylcysteine lyase ThiF PF00899.21 EAN34196.1 - 2.1e-27 96.0 0.1 3.3e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 EAN34196.1 - 1.3e-10 41.4 3.0 1.9e-10 40.9 3.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 EAN34196.1 - 0.0043 17.1 0.1 4.1 7.5 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EAN34196.1 - 0.079 13.4 0.1 0.62 10.5 0.1 2.3 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 EAN34196.1 - 0.19 12.0 0.0 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain PLU-1 PF08429.11 EAN34197.1 - 1.4e-58 198.7 20.0 1.4e-58 198.7 20.0 2.4 2 1 0 2 2 2 2 PLU-1-like protein Spem1 PF15670.5 EAN34197.1 - 0.86 9.1 9.1 0.095 12.3 3.2 2.5 3 1 0 3 3 3 0 Spermatid maturation protein 1 EGF_3 PF12947.7 EAN34198.1 - 0.00029 21.0 32.2 0.0067 16.6 8.8 3.6 3 0 0 3 3 3 3 EGF domain hEGF PF12661.7 EAN34198.1 - 0.0094 16.6 2.5 0.0094 16.6 2.5 3.8 3 0 0 3 3 3 2 Human growth factor-like EGF FXa_inhibition PF14670.6 EAN34198.1 - 0.033 14.5 5.9 0.033 14.5 5.9 3.5 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site FOG_N PF15888.5 EAN34198.1 - 0.49 10.8 4.0 0.43 11.0 0.2 2.7 3 0 0 3 3 3 0 Folded gastrulation N-terminus EGF_2 PF07974.13 EAN34198.1 - 3.5 8.1 24.6 3.1 8.2 1.5 4.0 3 2 0 3 3 3 0 EGF-like domain ABC_tran PF00005.27 EAN34199.1 - 7.1e-38 130.2 6.5 1.6e-16 61.0 0.1 5.1 3 2 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EAN34199.1 - 2.8e-17 63.5 13.5 4.3e-08 33.3 7.2 4.2 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAN34199.1 - 1.8e-12 47.1 0.8 1.2e-06 28.2 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAN34199.1 - 4.7e-08 32.6 0.1 0.0028 17.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EAN34199.1 - 2.2e-07 31.4 0.0 0.022 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Roc PF08477.13 EAN34199.1 - 5e-06 26.7 0.1 0.088 13.0 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EAN34199.1 - 1.8e-05 24.6 0.3 0.13 12.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EAN34199.1 - 2.2e-05 24.5 0.3 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase RNA_helicase PF00910.22 EAN34199.1 - 6.9e-05 23.2 0.9 2.2 8.7 0.0 4.1 3 0 0 3 3 3 1 RNA helicase MMR_HSR1 PF01926.23 EAN34199.1 - 8.4e-05 22.6 0.2 0.26 11.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase KAP_NTPase PF07693.14 EAN34199.1 - 0.00017 21.0 0.8 0.18 11.0 0.0 3.0 3 0 0 3 3 3 2 KAP family P-loop domain AAA_7 PF12775.7 EAN34199.1 - 0.00026 20.6 0.9 1.1 8.7 0.1 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_22 PF13401.6 EAN34199.1 - 0.0004 20.7 0.0 0.34 11.2 0.0 3.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EAN34199.1 - 0.00044 19.5 0.1 0.23 10.6 0.0 2.9 3 0 0 3 3 2 1 NB-ARC domain DUF5082 PF16888.5 EAN34199.1 - 0.00055 20.2 3.2 0.0014 18.9 3.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) NACHT PF05729.12 EAN34199.1 - 0.00069 19.6 0.0 0.076 12.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 EAN34199.1 - 0.00073 20.1 0.1 1.9 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EAN34199.1 - 0.00085 19.9 22.8 0.34 11.4 0.0 3.9 4 1 0 4 4 2 2 AAA domain Septin PF00735.18 EAN34199.1 - 0.0011 18.3 0.2 0.26 10.5 0.0 2.5 2 0 0 2 2 2 1 Septin SKA2 PF16740.5 EAN34199.1 - 0.0033 17.2 2.7 0.013 15.3 0.4 2.7 3 0 0 3 3 2 1 Spindle and kinetochore-associated protein 2 AAA_5 PF07728.14 EAN34199.1 - 0.0043 17.1 0.1 2.8 7.9 0.2 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EAN34199.1 - 0.0054 16.8 0.5 1.3 9.0 0.0 3.7 3 0 0 3 3 2 1 AAA domain Seryl_tRNA_N PF02403.22 EAN34199.1 - 0.0066 16.7 1.5 0.0066 16.7 1.5 1.9 2 0 0 2 2 1 1 Seryl-tRNA synthetase N-terminal domain Sigma54_activat PF00158.26 EAN34199.1 - 0.0072 16.0 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 EAN34199.1 - 0.0074 16.7 0.0 1.5 9.3 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 EAN34199.1 - 0.016 14.8 0.0 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Ras family NTPase_1 PF03266.15 EAN34199.1 - 0.044 13.7 0.2 12 5.7 0.1 2.8 2 0 0 2 2 2 0 NTPase ATP-synt_ab PF00006.25 EAN34199.1 - 0.053 13.2 0.0 7.5 6.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 EAN34199.1 - 0.095 12.7 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3584 PF12128.8 EAN34199.1 - 0.095 10.2 4.1 1.2 6.5 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) VirE PF05272.11 EAN34199.1 - 0.1 12.3 0.7 4.4 7.0 0.2 3.0 3 0 0 3 3 3 0 Virulence-associated protein E AAA_32 PF13654.6 EAN34199.1 - 0.25 10.1 4.0 0.61 8.8 0.5 3.0 4 0 0 4 4 4 0 AAA domain FlxA PF14282.6 EAN34199.1 - 0.56 10.2 3.7 1.4 9.0 3.7 1.6 1 0 0 1 1 1 0 FlxA-like protein eIF-4B PF06273.11 EAN34199.1 - 0.85 8.6 2.8 1.5 7.8 2.8 1.3 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B EAP30 PF04157.16 EAN34200.1 - 4.9e-11 42.4 0.7 7.5e-11 41.8 0.7 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family MitMem_reg PF13012.6 EAN34200.1 - 0.034 14.6 0.5 0.079 13.4 0.5 1.6 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function PUB PF09409.10 EAN34200.1 - 0.1 12.5 1.1 14 5.7 0.1 2.7 2 0 0 2 2 2 0 PUB domain RRM_1 PF00076.22 EAN34201.1 - 9.4e-12 44.6 0.0 1.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAN34201.1 - 0.028 14.3 0.0 0.093 12.6 0.0 1.9 2 1 0 2 2 2 0 Occluded RNA-recognition motif Ribosomal_L29 PF00831.23 EAN34202.1 - 5.9e-16 58.2 1.3 5.9e-16 58.2 1.3 2.6 2 1 0 2 2 2 1 Ribosomal L29 protein DUF4541 PF15074.6 EAN34202.1 - 0.03 14.9 0.7 0.044 14.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) PGK PF00162.19 EAN34203.1 - 4.5e-143 476.8 0.0 5.1e-143 476.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.11 EAN34203.1 - 0.16 11.5 0.0 6.8 6.2 0.0 2.6 2 1 1 3 3 3 0 Propionate catabolism activator FAINT PF04385.15 EAN34204.1 - 6.9e-11 42.1 12.2 4.4e-06 26.7 3.4 3.6 3 0 0 3 3 3 3 Domain of unknown function, DUF529 OGG_N PF07934.12 EAN34206.1 - 3.1e-17 62.8 0.1 8.8e-17 61.3 0.1 1.8 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EAN34206.1 - 9.2e-13 48.6 0.0 1.4e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EAN34206.1 - 0.00015 21.4 0.0 0.0026 17.6 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EAN34206.1 - 0.14 12.7 0.0 1.4 9.6 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.7 EAN34206.1 - 0.17 12.0 0.0 26 5.0 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif ClpS PF02617.17 EAN34207.1 - 3.1e-14 52.5 0.0 5.9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Peptidase_S26 PF10502.9 EAN34208.1 - 5.7e-05 22.9 0.0 0.0012 18.6 0.0 2.0 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 EAN34208.1 - 0.044 13.7 0.2 0.096 12.7 0.2 1.6 1 1 0 1 1 1 0 Peptidase S24-like FAINT PF04385.15 EAN34210.1 - 2.3e-16 59.6 0.2 5.3e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function, DUF529 SH3_1 PF00018.28 EAN34210.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 SH3 domain zf-C3HC4_3 PF13920.6 EAN34211.1 - 0.0042 16.9 4.8 0.0042 16.9 4.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAN34211.1 - 2.2 8.2 8.8 0.32 10.9 4.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RNA_pol PF00940.19 EAN34213.1 - 5.7e-137 456.9 2.6 7.3e-135 450.0 1.9 3.3 2 1 0 2 2 2 2 DNA-dependent RNA polymerase RPOL_N PF14700.6 EAN34213.1 - 7.5e-18 65.0 1.4 8.8e-09 35.2 0.0 3.1 1 1 0 2 2 2 2 DNA-directed RNA polymerase N-terminal HrpE PF06188.12 EAN34214.1 - 0.071 13.0 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E AGOG PF09171.10 EAN34214.1 - 0.079 12.3 2.2 0.34 10.2 2.5 1.8 2 0 0 2 2 2 0 N-glycosylase/DNA lyase DUF445 PF04286.12 EAN34214.1 - 0.12 12.1 3.2 0.21 11.4 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) ubiquitin PF00240.23 EAN34215.1 - 6.2e-06 25.9 0.1 8e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family FTH PF01827.27 EAN34215.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 FTH domain PDR_CDR PF06422.12 EAN34215.1 - 0.027 14.4 0.9 0.046 13.6 0.9 1.3 1 0 0 1 1 1 0 CDR ABC transporter Rad60-SLD_2 PF13881.6 EAN34215.1 - 0.027 14.5 0.0 0.063 13.4 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DNA_pol3_delta2 PF13177.6 EAN34216.1 - 4e-14 52.7 0.1 2.9e-13 49.9 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EAN34216.1 - 8.3e-12 45.7 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EAN34216.1 - 3e-10 40.3 0.0 6.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_30 PF13604.6 EAN34216.1 - 8.7e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAN34216.1 - 4.8e-06 26.6 0.0 6.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EAN34216.1 - 7.8e-06 25.9 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_19 PF13245.6 EAN34216.1 - 6.6e-05 23.3 0.1 0.00021 21.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAN34216.1 - 0.00011 22.5 0.0 0.00044 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EAN34216.1 - 0.00022 21.5 0.0 0.00085 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 EAN34216.1 - 0.00023 21.0 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.14 EAN34216.1 - 0.00029 20.9 0.0 0.00055 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EAN34216.1 - 0.0011 18.8 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EAN34216.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DEAD PF00270.29 EAN34216.1 - 0.0023 17.7 0.2 1 9.1 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.6 EAN34216.1 - 0.0099 16.3 0.0 0.05 14.0 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 EAN34216.1 - 0.016 14.7 0.5 0.15 11.4 0.0 2.1 1 1 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 EAN34216.1 - 0.017 15.1 0.1 0.57 10.2 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EAN34216.1 - 0.017 14.8 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein TIP49 PF06068.13 EAN34216.1 - 0.019 14.2 0.2 0.071 12.3 0.0 1.9 2 1 1 3 3 3 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EAN34216.1 - 0.019 14.3 0.1 0.25 10.7 0.0 2.4 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI Hydin_ADK PF17213.3 EAN34216.1 - 0.036 14.3 0.1 0.062 13.6 0.1 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_25 PF13481.6 EAN34216.1 - 0.037 13.6 0.0 0.072 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EAN34216.1 - 0.046 13.0 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 EAN34216.1 - 0.05 12.3 0.0 0.07 11.8 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_33 PF13671.6 EAN34216.1 - 0.065 13.4 0.1 0.12 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EAN34216.1 - 0.13 12.0 0.0 0.81 9.4 0.0 2.1 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 EAN34216.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_6 PF13174.6 EAN34216.1 - 0.28 11.9 0.9 6.1 7.7 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Ribosomal_S26e PF01283.19 EAN34218.1 - 7.8e-48 161.4 9.9 8.8e-48 161.2 9.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e SRP19 PF01922.17 EAN34218.1 - 0.014 16.4 0.5 0.028 15.3 0.5 1.6 1 1 0 1 1 1 0 SRP19 protein Eapp_C PF10238.9 EAN34219.1 - 3.9e-23 82.2 7.7 1.1e-21 77.5 7.7 2.0 1 1 0 1 1 1 1 E2F-associated phosphoprotein Pkinase PF00069.25 EAN34221.1 - 1.5e-77 260.5 0.0 2.4e-77 259.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN34221.1 - 4.2e-40 137.7 0.0 9.9e-40 136.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EAN34221.1 - 8.9e-27 90.6 6.7 3.3e-06 26.3 1.6 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAN34221.1 - 2.6e-23 82.3 2.7 2.6e-11 43.8 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EAN34221.1 - 7e-23 79.1 8.2 5.3e-06 25.7 0.8 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EAN34221.1 - 4.9e-21 72.8 5.9 0.00016 21.3 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EAN34221.1 - 2.7e-14 52.7 6.4 0.01 15.6 0.2 4.7 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EAN34221.1 - 4.7e-09 36.5 1.4 0.0062 16.8 0.0 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 EAN34221.1 - 2.6e-06 27.0 0.0 5.9e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAN34221.1 - 3.7e-05 22.7 0.0 6.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_4 PF12763.7 EAN34221.1 - 0.0009 19.2 3.9 0.21 11.5 0.1 3.4 1 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 EAN34221.1 - 0.0034 16.8 0.0 0.007 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DEK_C PF08766.11 EAN34221.1 - 0.0098 15.8 0.4 0.12 12.3 0.3 2.5 2 0 0 2 2 2 1 DEK C terminal domain FTA2 PF13095.6 EAN34221.1 - 0.037 13.7 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAN34221.1 - 0.055 13.4 0.0 0.16 11.8 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Dockerin_1 PF00404.18 EAN34221.1 - 2.5 8.4 6.6 6.4 7.0 0.4 3.7 3 2 1 4 4 3 0 Dockerin type I domain TSP_1 PF00090.19 EAN34222.1 - 3.3e-06 27.2 2.9 5.9e-06 26.4 1.3 2.4 2 0 0 2 2 2 1 Thrombospondin type 1 domain WD40 PF00400.32 EAN34224.1 - 1.8e-09 38.1 12.0 7.1e-05 23.5 1.0 6.3 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN34224.1 - 4.4e-06 26.9 0.0 0.1 12.9 0.0 3.8 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAN34224.1 - 0.00018 21.5 0.5 0.83 9.5 0.2 3.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A SGL PF08450.12 EAN34224.1 - 0.075 12.6 0.4 6.8 6.2 0.1 2.5 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region FAINT PF04385.15 EAN34225.1 - 2.8e-15 56.1 11.7 4e-06 26.8 0.2 5.9 5 0 0 5 5 5 3 Domain of unknown function, DUF529 Filamin PF00630.19 EAN34225.1 - 0.15 12.9 0.4 1.9 9.3 0.1 2.9 3 0 0 3 3 3 0 Filamin/ABP280 repeat Complex1_LYR_2 PF13233.6 EAN34225.1 - 1.2 9.9 5.9 2.9 8.7 5.9 1.6 1 0 0 1 1 1 0 Complex1_LYR-like Macoilin PF09726.9 EAN34225.1 - 1.9 6.9 15.0 2.9 6.4 15.0 1.1 1 0 0 1 1 1 0 Macoilin family Protocadherin PF08374.11 EAN34225.1 - 3.4 7.6 5.7 6.3 6.7 5.7 1.3 1 0 0 1 1 1 0 Protocadherin VSG_B PF13206.6 EAN34225.1 - 6.4 5.9 8.5 10 5.3 8.5 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain Tfb2 PF03849.14 EAN34226.1 - 8.5e-20 71.0 6.3 3.6e-19 69.0 6.3 1.8 1 1 0 1 1 1 1 Transcription factor Tfb2 Tfb2 PF03849.14 EAN34227.1 - 4.2e-39 134.5 1.1 6.8e-39 133.8 1.1 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EAN34227.1 - 0.0026 18.1 0.6 0.0065 16.9 0.6 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EAN34227.1 - 0.0055 16.9 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PH PF00169.29 EAN34228.1 - 0.0058 17.1 0.6 0.012 16.1 0.2 1.7 1 1 1 2 2 2 1 PH domain Synaptobrevin PF00957.21 EAN34229.1 - 4.8e-07 29.5 0.9 9e-07 28.6 0.9 1.5 1 0 0 1 1 1 1 Synaptobrevin I_LWEQ PF01608.17 EAN34229.1 - 0.0076 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 I/LWEQ domain LSM PF01423.22 EAN34230.1 - 4.6e-16 58.3 0.0 5e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAN34230.1 - 0.04 14.0 0.0 0.045 13.9 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Pribosyltran_N PF13793.6 EAN34232.1 - 4.7e-36 123.2 0.0 3.6e-35 120.4 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EAN34232.1 - 8.9e-25 87.8 2.6 4.1e-24 85.6 0.2 2.6 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EAN34232.1 - 2.3e-10 40.2 0.8 5.9e-10 38.9 0.8 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EAN34232.1 - 0.0025 17.3 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HHH_5 PF14520.6 EAN34235.1 - 1.3e-05 25.7 0.0 1.6e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain BORCS8 PF10167.9 EAN34236.1 - 0.032 14.2 2.9 0.056 13.4 2.9 1.5 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 Allexi_40kDa PF05549.11 EAN34236.1 - 0.057 12.9 2.3 0.07 12.6 2.3 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1664 PF07889.12 EAN34236.1 - 0.18 11.9 5.7 0.27 11.3 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 EAN34236.1 - 0.5 10.8 4.5 3.4 8.2 1.0 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 EAN34236.1 - 0.51 11.0 5.4 2.8 8.6 0.8 2.5 1 1 1 2 2 2 0 SlyX DUF4510 PF14971.6 EAN34236.1 - 0.78 10.1 3.1 14 6.0 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4510) DUF641 PF04859.12 EAN34236.1 - 0.8 10.0 7.1 0.3 11.4 0.8 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF5320 PF17253.2 EAN34236.1 - 1.2 10.2 6.7 1.7 9.8 0.9 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF1192 PF06698.11 EAN34236.1 - 2.2 8.4 5.1 23 5.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) zf-C4H2 PF10146.9 EAN34238.1 - 0.063 13.6 0.2 0.063 13.6 0.2 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein APG6_N PF17675.1 EAN34238.1 - 1.9 9.0 18.1 0.22 12.1 11.4 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Rop PF01815.16 EAN34239.1 - 0.11 12.4 0.7 2.9 7.8 0.0 2.8 2 0 0 2 2 2 0 Rop protein NFACT-R_1 PF05670.13 EAN34240.1 - 1.9e-09 38.1 0.7 3.8e-09 37.2 0.7 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 EAN34240.1 - 3.1e-09 37.0 0.1 7.5e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain tRNA-synt_2c PF01411.19 EAN34242.1 - 1.3e-183 611.5 0.0 1.9e-183 610.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EAN34242.1 - 4.9e-12 45.7 1.3 1.9e-11 43.8 0.6 2.4 3 0 0 3 3 3 1 Threonyl and Alanyl tRNA synthetase second additional domain Vps53_N PF04100.12 EAN34243.1 - 2.6e-42 145.2 7.2 3.1e-42 144.9 7.2 1.0 1 0 0 1 1 1 1 Vps53-like, N-terminal GLTP PF08718.11 EAN34243.1 - 0.028 14.7 0.3 0.028 14.7 0.3 2.0 2 1 0 2 2 2 0 Glycolipid transfer protein (GLTP) COG5 PF10392.9 EAN34243.1 - 0.046 13.9 11.3 0.44 10.7 2.8 3.6 3 1 0 3 3 3 0 Golgi transport complex subunit 5 Vps53_N PF04100.12 EAN34244.1 - 0.0003 19.9 0.4 0.0028 16.7 0.0 2.4 2 1 0 2 2 2 1 Vps53-like, N-terminal DRE2_N PF16803.5 EAN34244.1 - 0.029 14.6 0.5 0.24 11.6 0.1 2.5 3 0 0 3 3 3 0 Fe-S cluster assembly protein DRE2 N-terminus Cullin_binding PF03556.15 EAN34244.1 - 0.11 13.0 0.4 0.4 11.1 0.1 2.1 2 1 0 2 2 2 0 Cullin binding NIF PF03031.18 EAN34245.1 - 1.8e-35 122.0 0.4 3.1e-35 121.2 0.4 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Presenilin PF01080.17 EAN34245.1 - 0.054 12.2 1.5 0.073 11.8 1.5 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EAN34245.1 - 0.087 12.0 0.3 0.12 11.6 0.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DWNN PF08783.11 EAN34246.1 - 1.3e-09 38.2 1.1 3.6e-09 36.8 0.1 2.4 2 0 0 2 2 2 1 DWNN domain zf-RING_UBOX PF13445.6 EAN34246.1 - 0.57 10.3 14.7 2.4 8.2 8.5 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAN34246.1 - 5.6 6.9 15.5 19 5.2 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PseudoU_synth_2 PF00849.22 EAN34247.1 - 1.8e-25 89.9 0.0 2.8e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Meiosis_expr PF15163.6 EAN34247.1 - 0.077 13.7 0.2 3.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Meiosis-expressed Tcf25 PF04910.14 EAN34248.1 - 9.9e-27 93.9 0.7 5.7e-26 91.4 0.1 2.0 1 1 1 2 2 2 1 Transcriptional repressor TCF25 Actin PF00022.19 EAN34250.1 - 1.1e-50 172.5 0.0 9.7e-50 169.4 0.0 1.9 1 1 0 1 1 1 1 Actin MtN3_slv PF03083.16 EAN34251.1 - 2.7e-24 85.0 17.7 4.3e-13 49.1 2.8 2.9 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange LAB_N PF07578.11 EAN34251.1 - 0.011 15.8 3.8 2.3 8.4 0.3 2.7 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain SNAPc_SNAP43 PF09808.9 EAN34252.1 - 5.2e-09 36.3 2.3 6.5e-09 36.0 2.3 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Lig_chan PF00060.26 EAN34252.1 - 0.015 15.2 0.2 0.017 15.0 0.2 1.2 1 0 0 1 1 1 0 Ligand-gated ion channel ATP_bind_1 PF03029.17 EAN34253.1 - 4.2e-65 219.9 0.2 4.8e-65 219.7 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EAN34253.1 - 0.00037 20.3 0.0 0.0015 18.3 0.0 1.9 1 1 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_31 PF13614.6 EAN34253.1 - 0.00052 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAN34253.1 - 0.0007 19.9 0.0 0.0025 18.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EAN34253.1 - 0.00073 19.1 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 EAN34253.1 - 0.006 16.7 0.0 0.038 14.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.14 EAN34253.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MeaB PF03308.16 EAN34253.1 - 0.0068 15.4 0.0 0.0099 14.9 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EAN34253.1 - 0.0073 16.7 0.0 0.01 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 EAN34253.1 - 0.009 16.4 0.1 0.023 15.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAN34253.1 - 0.0093 16.5 0.1 0.02 15.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain CbiA PF01656.23 EAN34253.1 - 0.015 15.3 0.0 0.02 14.9 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 EAN34253.1 - 0.03 14.7 0.0 0.081 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EAN34253.1 - 0.033 13.7 0.0 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 EAN34253.1 - 0.038 13.6 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArsA_ATPase PF02374.15 EAN34253.1 - 0.041 13.1 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_29 PF13555.6 EAN34253.1 - 0.042 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EAN34253.1 - 0.047 13.8 0.0 0.088 13.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EAN34253.1 - 0.055 13.5 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 EAN34253.1 - 0.066 12.7 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Zeta_toxin PF06414.12 EAN34253.1 - 0.098 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ADK PF00406.22 EAN34253.1 - 0.18 11.9 0.1 0.96 9.5 0.1 2.0 2 1 0 2 2 2 0 Adenylate kinase AAA_24 PF13479.6 EAN34253.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAN34253.1 - 0.21 11.3 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ThiF PF00899.21 EAN34255.1 - 2.7e-46 157.9 0.1 4.7e-46 157.1 0.1 1.3 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EAN34255.1 - 2.8e-05 24.6 0.0 0.00012 22.6 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 EAN34255.1 - 0.022 14.8 0.0 0.1 12.7 0.0 1.9 1 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ntox35 PF15534.6 EAN34256.1 - 0.00046 20.6 0.0 0.029 14.8 0.0 2.7 2 0 0 2 2 2 1 Bacterial toxin 35 DnaJ PF00226.31 EAN34256.1 - 0.035 14.2 0.2 0.095 12.8 0.2 1.8 1 0 0 1 1 1 0 DnaJ domain HA2 PF04408.23 EAN34257.1 - 1.6e-20 73.4 0.0 3.4e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAN34257.1 - 2.5e-18 66.2 0.3 1.3e-17 63.9 0.1 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAN34257.1 - 2.8e-12 47.0 0.0 6.5e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAN34257.1 - 5.1e-08 32.9 1.3 9.8e-08 32.0 1.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAN34257.1 - 1.7e-06 28.4 0.2 3.6e-05 24.0 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAN34257.1 - 8.1e-05 23.0 1.1 0.00015 22.1 1.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAN34257.1 - 8.5e-05 22.6 0.3 0.0022 18.0 0.3 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EAN34257.1 - 0.00014 21.6 0.3 0.00026 20.8 0.3 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EAN34257.1 - 0.0033 17.4 0.3 0.0062 16.5 0.3 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_7 PF12775.7 EAN34257.1 - 0.0093 15.5 0.0 0.029 13.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 EAN34257.1 - 0.0098 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 EAN34257.1 - 0.011 15.5 0.5 1.5 8.5 0.0 2.3 1 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EAN34257.1 - 0.013 15.0 0.2 0.041 13.3 0.1 1.9 3 0 0 3 3 3 0 PhoH-like protein SRP54 PF00448.22 EAN34257.1 - 0.015 14.9 0.2 0.026 14.1 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EAN34257.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAN34257.1 - 0.023 14.3 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EAN34257.1 - 0.043 14.3 0.0 0.083 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAN34257.1 - 0.06 13.9 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 EAN34257.1 - 0.066 13.3 0.3 2.2 8.3 0.4 2.8 2 1 0 2 2 1 0 AAA domain Helicase_RecD PF05127.14 EAN34257.1 - 0.077 12.8 0.3 0.45 10.4 0.1 2.0 2 0 0 2 2 2 0 Helicase ATPase PF06745.13 EAN34257.1 - 0.082 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 KaiC Cue1_U7BR PF18499.1 EAN34257.1 - 0.15 12.1 0.1 0.45 10.6 0.1 1.8 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 NACHT PF05729.12 EAN34257.1 - 0.16 11.8 0.5 0.38 10.6 0.2 1.8 2 0 0 2 2 1 0 NACHT domain DUF2207 PF09972.9 EAN34258.1 - 0.39 9.4 5.7 3.8 6.2 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1980 PF09323.10 EAN34258.1 - 0.51 10.2 4.2 0.17 11.8 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) zf-C3HC4_3 PF13920.6 EAN34260.1 - 4.5e-13 48.8 5.0 9.1e-13 47.9 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAN34260.1 - 4.9e-08 32.7 5.5 4.9e-08 32.7 5.5 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EAN34260.1 - 3.1e-06 27.0 7.1 8.2e-06 25.6 7.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAN34260.1 - 1.1e-05 25.6 7.9 1.1e-05 25.6 7.9 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAN34260.1 - 0.00012 21.8 7.4 0.00031 20.5 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAN34260.1 - 0.00013 21.9 7.1 0.00029 20.7 6.5 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAN34260.1 - 0.098 12.7 8.1 0.28 11.2 5.1 2.8 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EAN34260.1 - 0.13 12.4 5.9 1.1 9.5 6.1 2.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 EAN34260.1 - 0.16 11.9 0.3 0.39 10.6 0.3 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 EAN34260.1 - 0.69 9.8 5.7 1.6 8.6 5.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RL10P_insert PF17777.1 EAN34261.1 - 1.9e-22 79.1 0.0 3.3e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EAN34261.1 - 9.8e-13 48.1 0.8 2.3e-12 46.9 0.8 1.5 1 1 0 1 1 1 1 Ribosomal protein L10 tRNA-synt_1d PF00750.19 EAN34262.1 - 6.1e-46 157.0 5.8 3.4e-25 88.8 2.5 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 EAN34262.1 - 3.8e-20 72.3 0.0 7.7e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Bromo_TP_like PF17027.5 EAN34262.1 - 0.25 11.5 5.5 0.3 11.2 0.2 3.2 3 0 0 3 3 3 0 Histone-fold protein DUF3660 PF12398.8 EAN34264.1 - 0.11 12.6 0.2 0.28 11.3 0.2 1.7 1 0 0 1 1 1 0 Receptor serine/threonine kinase UTP15_C PF09384.10 EAN34265.1 - 2.3e-19 69.6 1.6 2.5e-15 56.4 0.7 2.4 2 0 0 2 2 2 2 UTP15 C terminal WD40 PF00400.32 EAN34265.1 - 1.8e-11 44.4 13.1 0.00069 20.4 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN34265.1 - 1.1e-05 25.6 0.0 1.4 9.3 0.0 4.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAN34265.1 - 0.18 10.8 1.1 3.2 6.6 0.0 3.0 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 EAN34266.1 - 4e-35 121.5 0.4 4.7e-35 121.2 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN34266.1 - 7.2e-14 51.7 0.1 8.6e-14 51.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase AsnC_trans_reg PF01037.21 EAN34266.1 - 0.0055 16.7 0.2 0.036 14.0 0.2 2.0 1 1 0 1 1 1 1 Lrp/AsnC ligand binding domain Kinase-like PF14531.6 EAN34266.1 - 0.015 14.6 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.32 EAN34268.1 - 1.6e-05 25.5 1.3 1.9 9.5 0.1 5.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN34268.1 - 0.006 16.9 0.6 3.4 8.0 0.0 3.8 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Colicin_immun PF09204.10 EAN34268.1 - 0.058 13.9 0.1 0.25 11.9 0.1 2.1 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity AAR2 PF05282.11 EAN34269.1 - 3e-68 230.8 3.0 3.9e-68 230.5 3.0 1.1 1 0 0 1 1 1 1 AAR2 protein RRM_1 PF00076.22 EAN34270.1 - 7.7e-23 80.1 0.2 1.8e-22 78.9 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAN34270.1 - 0.00011 21.8 0.6 0.00022 20.8 0.6 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAN34270.1 - 0.00034 20.7 0.1 0.0011 19.1 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 EAN34270.1 - 0.0018 18.1 0.8 0.0061 16.4 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF4564 PF15169.6 EAN34270.1 - 0.014 15.1 3.0 0.023 14.4 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) RL PF17797.1 EAN34270.1 - 0.027 14.4 0.1 0.069 13.1 0.1 1.7 1 0 0 1 1 1 0 RL domain Thr_dehydrat_C PF00585.18 EAN34270.1 - 0.029 14.1 1.4 0.29 10.9 0.1 2.3 2 0 0 2 2 2 0 C-terminal regulatory domain of Threonine dehydratase Lipoprotein_18 PF06804.11 EAN34270.1 - 0.036 13.1 0.5 0.45 9.5 0.1 2.1 1 1 1 2 2 2 0 NlpB/DapX lipoprotein Peripla_BP_4 PF13407.6 EAN34270.1 - 0.042 13.4 0.0 0.098 12.2 0.0 1.6 1 1 1 2 2 2 0 Periplasmic binding protein domain PHM7_cyt PF14703.6 EAN34270.1 - 0.049 13.9 8.4 99 3.1 8.4 3.2 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter ZinT PF09223.11 EAN34270.1 - 0.15 11.9 3.1 0.28 11.0 0.3 2.6 1 1 2 3 3 3 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment NPV_P10 PF05531.12 EAN34270.1 - 0.27 11.7 2.4 8.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.8 EAN34270.1 - 0.57 10.2 11.1 2.5 8.2 4.4 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Rad50_zn_hook PF04423.14 EAN34270.1 - 1 9.3 4.3 8.9 6.2 2.2 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Organ_specific PF10950.8 EAN34270.1 - 4.5 8.0 6.5 0.77 10.5 2.2 1.8 2 0 0 2 2 2 0 Organ specific protein WD40 PF00400.32 EAN34271.1 - 0.028 15.3 2.9 69 4.6 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Hira PF07569.11 EAN34271.1 - 0.087 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split HEPN PF05168.14 EAN34272.1 - 0.0017 18.5 0.3 0.086 13.0 0.0 2.5 2 1 0 2 2 2 1 HEPN domain YlbD_coat PF14071.6 EAN34272.1 - 0.01 16.1 5.9 0.058 13.7 4.8 2.6 1 1 0 2 2 2 0 Putative coat protein KIX_2 PF16987.5 EAN34272.1 - 0.022 14.7 2.3 0.16 12.0 0.2 2.4 2 1 0 2 2 2 0 KIX domain LigA PF07746.11 EAN34272.1 - 0.22 11.7 0.9 2.9 8.1 0.2 2.3 2 0 0 2 2 2 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit DUF1759 PF03564.15 EAN34272.1 - 0.42 10.6 5.5 3.8 7.4 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) BLOC1_2 PF10046.9 EAN34272.1 - 0.76 10.1 7.1 0.72 10.2 5.3 1.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myb_DNA-binding PF00249.31 EAN34273.1 - 9.1e-08 32.2 2.3 0.00021 21.4 0.3 4.1 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAN34273.1 - 3.3e-06 27.2 0.8 3.3e-06 27.2 0.8 4.3 6 0 0 6 6 6 1 Myb-like DNA-binding domain Med9 PF07544.13 EAN34273.1 - 0.012 15.7 0.4 0.25 11.4 0.2 2.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2680 PF10925.8 EAN34273.1 - 0.019 14.9 0.4 0.5 10.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) 7TMR-HDED PF07697.11 EAN34273.1 - 0.03 14.4 2.1 0.09 12.9 1.1 1.9 2 1 0 2 2 2 0 7TM-HD extracellular RAP PF08373.10 EAN34274.1 - 5.8e-15 55.1 6.7 7.1e-14 51.6 1.0 3.1 2 0 0 2 2 2 2 RAP domain DUF559 PF04480.12 EAN34274.1 - 0.054 13.4 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF559) v110 PF01639.17 EAN34274.1 - 0.1 12.5 1.2 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 Viral family 110 ThylakoidFormat PF11264.8 EAN34275.1 - 0.021 14.5 5.5 0.044 13.5 5.5 1.6 1 0 0 1 1 1 0 Thylakoid formation protein Hormone_1 PF00103.20 EAN34275.1 - 0.17 11.6 5.9 0.027 14.2 2.0 1.6 2 0 0 2 2 2 0 Somatotropin hormone family Laminin_II PF06009.12 EAN34275.1 - 0.17 11.9 4.8 0.34 10.9 4.8 1.4 1 0 0 1 1 1 0 Laminin Domain II GLE1 PF07817.13 EAN34275.1 - 0.27 10.4 2.5 0.49 9.6 2.5 1.4 1 0 0 1 1 1 0 GLE1-like protein DUF4407 PF14362.6 EAN34275.1 - 0.32 10.3 0.9 0.49 9.7 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) U3_assoc_6 PF08640.11 EAN34275.1 - 0.34 11.0 7.7 1.4 9.0 7.7 2.1 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 OmpH PF03938.14 EAN34275.1 - 0.67 10.3 8.6 1.2 9.5 8.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3810 PF12725.7 EAN34275.1 - 1.4 8.2 3.8 2.5 7.4 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) FapA PF03961.13 EAN34275.1 - 2.5 6.6 6.5 3.4 6.2 6.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rho_Binding PF08912.11 EAN34275.1 - 4.8 8.1 15.8 0.9 10.4 5.9 2.6 1 1 1 2 2 2 0 Rho Binding TMPIT PF07851.13 EAN34275.1 - 5 6.3 8.0 11 5.1 8.0 1.5 1 0 0 1 1 1 0 TMPIT-like protein Nipped-B_C PF12830.7 EAN34277.1 - 0.0066 16.4 2.7 0.076 12.9 0.1 3.3 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Rad60-SLD PF11976.8 EAN34278.1 - 5e-24 83.9 0.0 6.6e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAN34278.1 - 7.4e-12 44.8 0.0 9.9e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.20 EAN34278.1 - 0.02 15.1 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 UBX domain CLP_protease PF00574.23 EAN34279.1 - 4.8e-60 202.6 0.0 5.3e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Clp protease Ephrin_rec_like PF07699.13 EAN34280.1 - 4.4e-34 116.0 118.4 5e-08 32.6 9.1 11.8 11 1 1 12 12 12 10 Putative ephrin-receptor like Orthopox_B11R PF07033.11 EAN34280.1 - 0.0057 16.4 1.8 0.049 13.4 1.8 2.7 1 0 0 1 1 1 1 Orthopoxvirus B11R protein PDR_assoc PF08370.11 EAN34280.1 - 1.5 8.7 8.4 0.96 9.2 3.8 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Ephrin_rec_like PF07699.13 EAN34281.1 - 8.1e-37 124.7 132.7 6e-09 35.5 9.2 12.1 11 1 2 13 13 12 10 Putative ephrin-receptor like ZapB PF06005.12 EAN34281.1 - 0.0053 17.2 7.0 0.011 16.1 7.0 1.6 1 0 0 1 1 1 1 Cell division protein ZapB APG6_N PF17675.1 EAN34281.1 - 0.0068 16.9 7.7 0.018 15.5 7.7 1.7 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF3450 PF11932.8 EAN34281.1 - 0.032 13.5 6.4 0.056 12.7 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0184 PF03670.13 EAN34281.1 - 0.048 14.0 1.7 0.14 12.6 1.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) UPF0242 PF06785.11 EAN34281.1 - 0.063 13.4 9.7 0.32 11.1 9.7 2.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SKA2 PF16740.5 EAN34281.1 - 0.16 11.7 3.1 0.33 10.7 3.1 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 EAN34281.1 - 0.47 10.3 8.5 0.48 10.2 6.0 2.4 1 1 1 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 EAN34281.1 - 0.73 10.1 5.9 2.1 8.7 5.9 1.8 1 1 0 1 1 1 0 ABC transporter C-terminal domain CCM2_C PF16545.5 EAN34281.1 - 0.79 10.3 3.8 0.59 10.7 0.4 2.4 2 0 0 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology FlaC_arch PF05377.11 EAN34281.1 - 0.95 9.9 5.6 4.2 7.8 5.6 2.1 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 EAN34281.1 - 0.95 9.4 9.5 0.34 10.9 5.8 2.2 1 1 1 2 2 2 0 Prefoldin subunit DUF4337 PF14235.6 EAN34281.1 - 2.2 8.4 6.3 5.4 7.1 6.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FliJ PF02050.16 EAN34281.1 - 5.3 7.3 13.1 3.6 7.8 6.6 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein DUF16 PF01519.16 EAN34281.1 - 5.9 7.4 8.7 0.42 11.1 3.2 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 Spc24 PF08286.11 EAN34281.1 - 6.1 7.2 12.8 0.24 11.6 5.4 2.6 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 RANK_CRD_2 PF18278.1 EAN34281.1 - 6.3 7.0 33.9 0.59 10.3 1.1 7.8 9 0 0 9 9 8 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Uds1 PF15456.6 EAN34281.1 - 9.6 6.4 7.7 6.4 7.0 0.5 1.8 1 1 1 2 2 2 0 Up-regulated During Septation GTP_EFTU PF00009.27 EAN34283.1 - 1e-39 136.1 0.7 1.9e-39 135.3 0.7 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EAN34283.1 - 1.8e-33 114.9 0.3 6.7e-33 113.1 0.4 1.9 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EAN34283.1 - 3.1e-20 72.0 0.0 1.1e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EAN34283.1 - 4.5e-10 39.8 0.3 1.3e-09 38.3 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EAN34283.1 - 2.8e-06 27.3 0.0 1.1e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 Elongation Factor G, domain II Porin_3 PF01459.22 EAN34284.1 - 3.1e-21 76.0 0.0 9e-21 74.5 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic porin Cas_Cas6 PF01881.16 EAN34284.1 - 0.073 13.6 0.4 0.18 12.3 0.3 1.7 1 1 0 1 1 1 0 CRISPR associated protein Cas6 Patatin PF01734.22 EAN34287.1 - 1.1e-08 35.5 0.1 1.5e-05 25.3 0.0 2.2 2 0 0 2 2 2 2 Patatin-like phospholipase Aconitase PF00330.20 EAN34288.1 - 2.3e-168 561.0 0.0 3e-168 560.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EAN34288.1 - 4.3e-42 143.5 0.0 7.4e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L2_C PF03947.18 EAN34289.1 - 4.4e-44 149.7 3.2 9.1e-44 148.7 3.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EAN34289.1 - 1.2e-17 63.6 0.5 3.5e-17 62.1 0.2 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain LBP_C PF17386.2 EAN34289.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase C-terminal domain RNase_PH PF01138.21 EAN34290.1 - 1.4e-16 61.2 0.0 2.2e-16 60.6 0.0 1.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 tRNA-synt_1c PF00749.21 EAN34291.1 - 2e-106 355.4 0.1 2.8e-106 355.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EAN34291.1 - 3.2e-29 102.0 2.9 6.4e-29 101.0 0.3 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 EAN34291.1 - 0.017 14.5 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain CDC14 PF08045.11 EAN34292.1 - 0.0074 15.4 0.2 0.014 14.5 0.2 1.4 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Aspzincin_M35 PF14521.6 EAN34293.1 - 0.047 14.2 0.1 0.076 13.6 0.1 1.3 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase EMA PF02488.15 EAN34294.1 - 9.3e-156 516.8 22.2 1.1e-155 516.6 22.2 1.0 1 0 0 1 1 1 1 Merozoite Antigen Orthopox_B11R PF07033.11 EAN34295.1 - 0.019 14.8 0.3 0.036 13.9 0.3 1.4 1 0 0 1 1 1 0 Orthopoxvirus B11R protein Myb_Cef PF11831.8 EAN34297.1 - 7.4e-29 101.0 8.4 7.4e-29 101.0 8.4 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EAN34297.1 - 2.5e-19 69.2 5.8 5.4e-11 42.5 1.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAN34297.1 - 1.8e-15 56.9 7.5 3e-11 43.4 2.8 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EAN34297.1 - 0.081 13.1 2.2 0.18 12.0 0.4 2.6 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 PRC2_HTH_1 PF18118.1 EAN34297.1 - 7.6 7.4 7.5 1.3 9.9 1.3 2.6 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain RAP PF08373.10 EAN34298.1 - 1.1e-15 57.4 1.9 2.5e-15 56.3 1.9 1.6 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 EAN34298.1 - 0.00023 21.3 0.0 0.00037 20.6 0.0 1.3 1 0 0 1 1 1 1 REase_MTES_1575 DUF2107 PF09880.9 EAN34298.1 - 0.16 12.1 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) Lpp-LpqN PF10738.9 EAN34299.1 - 0.14 11.7 0.0 8.3 5.8 0.0 2.2 1 1 1 2 2 2 0 Probable lipoprotein LpqN DNA_pol3_delta2 PF13177.6 EAN34300.1 - 1e-08 35.1 0.7 8.7e-07 28.9 0.1 2.6 3 0 0 3 3 3 2 DNA polymerase III, delta subunit AAA_16 PF13191.6 EAN34300.1 - 0.032 14.6 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain CNOT1_CAF1_bind PF16415.5 EAN34301.1 - 9.2e-75 250.9 3.3 2.3e-74 249.6 3.3 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 EAN34301.1 - 4e-41 140.3 4.4 1.2e-40 138.8 0.4 3.5 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 EAN34301.1 - 4.1e-37 127.3 4.9 1.7e-36 125.4 4.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Not1 PF04054.15 EAN34301.1 - 9e-28 97.2 5.7 5e-23 81.6 0.1 3.2 3 0 0 3 3 3 2 CCR4-Not complex component, Not1 Bacillus_HBL PF05791.11 EAN34303.1 - 0.011 15.6 0.4 0.045 13.6 0.4 2.0 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2977 PF11192.8 EAN34303.1 - 0.046 13.9 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2977) XhlA PF10779.9 EAN34303.1 - 0.059 13.6 0.3 0.2 11.9 0.3 1.9 1 0 0 1 1 1 0 Haemolysin XhlA Focal_AT PF03623.13 EAN34303.1 - 0.12 12.4 0.6 1.1 9.2 0.1 2.6 2 0 0 2 2 2 0 Focal adhesion targeting region DMPK_coil PF08826.10 EAN34303.1 - 0.17 12.0 1.7 0.73 10.0 1.7 2.2 1 0 0 1 1 1 0 DMPK coiled coil domain like Baculo_PEP_C PF04513.12 EAN34303.1 - 0.18 11.9 5.9 3.4 7.7 0.9 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HR1 PF02185.16 EAN34303.1 - 0.94 9.6 4.6 18 5.5 1.6 3.2 2 1 1 3 3 3 0 Hr1 repeat DnaJ PF00226.31 EAN34304.1 - 0.0092 16.1 0.3 0.12 12.6 0.3 2.2 1 1 0 1 1 1 1 DnaJ domain Gp-FAR-1 PF05823.12 EAN34304.1 - 0.1 12.9 0.1 17 5.8 0.0 2.4 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SNARE_assoc PF09335.11 EAN34305.1 - 1e-26 93.8 9.9 1e-26 93.8 9.9 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein Sugar_tr PF00083.24 EAN34307.1 - 3.3e-59 201.0 28.0 3.9e-59 200.7 28.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAN34307.1 - 5.3e-19 68.4 26.7 5.3e-19 68.4 26.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily ubiquitin PF00240.23 EAN34308.1 - 5.7e-35 118.9 0.3 7.4e-35 118.5 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 EAN34308.1 - 1.2e-30 105.2 11.0 1.8e-30 104.6 11.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EAN34308.1 - 5.9e-17 61.3 0.4 7.9e-17 60.9 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAN34308.1 - 6e-06 26.6 0.1 2.1e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EAN34308.1 - 0.0036 17.2 0.0 0.0048 16.8 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAN34308.1 - 0.0054 16.8 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EAN34308.1 - 0.0067 16.8 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EAN34308.1 - 0.024 14.7 0.7 6.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 EAN34308.1 - 0.059 13.9 0.0 0.069 13.7 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.6 EAN34308.1 - 1.5 8.8 5.0 74 3.4 4.1 2.5 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain HTH_20 PF12840.7 EAN34309.1 - 0.0011 19.0 1.5 0.0012 18.9 0.3 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 EAN34309.1 - 0.081 12.5 0.3 0.15 11.6 0.3 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GntR PF00392.21 EAN34309.1 - 0.092 12.4 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_5 PF01022.20 EAN34309.1 - 0.24 11.3 1.9 0.39 10.6 0.1 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family TGT PF01702.18 EAN34310.1 - 1.1e-132 442.4 0.0 1.4e-132 442.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Arm-DNA-bind_2 PF12167.8 EAN34310.1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain Pkinase PF00069.25 EAN34311.1 - 1.9e-78 263.4 1.1 2.6e-78 263.1 1.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAN34311.1 - 3.3e-41 141.3 0.0 4.5e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EAN34311.1 - 1.3e-26 90.1 9.0 7e-07 28.3 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAN34311.1 - 7.2e-24 84.0 9.7 2.1e-11 44.1 0.6 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EAN34311.1 - 1.3e-21 74.6 10.5 5.4e-05 22.8 0.1 4.9 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EAN34311.1 - 1.9e-19 69.2 11.7 1.7e-06 27.8 0.3 5.1 3 1 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 EAN34311.1 - 1.3e-18 65.6 7.9 8.9e-05 21.8 0.1 4.5 4 0 0 4 4 4 4 EF hand Kinase-like PF14531.6 EAN34311.1 - 2.8e-06 26.9 0.1 2e-05 24.0 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAN34311.1 - 3e-05 23.0 0.1 6.4e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAN34311.1 - 0.0006 19.2 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.9 EAN34311.1 - 0.0024 18.1 1.6 2 8.7 0.1 3.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region FTA2 PF13095.6 EAN34311.1 - 0.0089 15.7 0.5 0.88 9.2 0.1 2.4 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAN34311.1 - 0.021 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family EF-hand_4 PF12763.7 EAN34311.1 - 0.077 13.0 3.1 11 6.0 0.3 4.0 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Hydrolase_3 PF08282.12 EAN34312.1 - 4.8e-31 108.4 0.0 6.5e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAN34312.1 - 3.1e-06 26.9 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EAN34312.1 - 0.024 14.9 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase AcMNPV_Ac109 PF05054.12 EAN34312.1 - 0.073 12.1 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Hydrolase_3 PF08282.12 EAN34313.1 - 1.5e-30 106.8 1.8 5.8e-30 104.9 1.8 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAN34313.1 - 3.2e-06 26.8 0.0 0.013 15.0 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EAN34313.1 - 0.00061 20.1 0.0 0.026 14.8 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAN34313.1 - 0.0037 17.4 0.1 0.017 15.3 0.1 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EAN34313.1 - 0.069 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EAN34314.1 - 6.4e-34 117.8 0.5 1e-33 117.2 0.5 1.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAN34314.1 - 3.1e-07 30.2 0.0 0.0027 17.3 0.0 2.3 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EAN34314.1 - 2.5e-05 24.7 0.0 0.006 16.9 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EAN34314.1 - 0.0015 18.6 0.1 0.055 13.6 0.0 2.8 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Asp1 PF16993.5 EAN34314.1 - 0.025 13.8 0.5 0.034 13.4 0.5 1.2 1 0 0 1 1 1 0 Accessory Sec system protein Asp1 Hydrolase_3 PF08282.12 EAN34315.1 - 1.3e-34 120.2 3.9 2.2e-34 119.4 3.9 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAN34315.1 - 5.7e-07 29.3 0.0 0.00057 19.5 0.0 2.3 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EAN34315.1 - 7.5e-06 26.4 0.0 0.00026 21.4 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAN34315.1 - 0.00091 19.4 0.1 0.0031 17.6 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EAN34315.1 - 0.0023 18.0 0.2 0.043 13.9 0.0 2.7 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Asp1 PF16993.5 EAN34315.1 - 0.008 15.5 1.1 0.011 15.0 1.1 1.2 1 0 0 1 1 1 1 Accessory Sec system protein Asp1 Hydrolase_like PF13242.6 EAN34315.1 - 0.075 13.1 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_3 PF08282.12 EAN34316.1 - 2.7e-35 122.3 4.2 3.8e-35 121.9 4.2 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAN34316.1 - 4e-06 26.5 0.0 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EAN34316.1 - 0.054 13.8 0.0 7.4 6.8 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EAN34319.1 - 6.2e-32 111.3 1.9 2.3e-31 109.4 1.9 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAN34319.1 - 4.9e-07 29.5 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EAN34319.1 - 5.8e-05 23.5 0.0 0.0023 18.2 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAN34319.1 - 0.0031 17.6 0.1 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EAN34319.1 - 0.074 13.2 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EAN34320.1 - 2.3e-25 89.8 1.9 4e-25 89.0 1.9 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAN34320.1 - 6.3e-05 22.6 0.0 0.0085 15.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_6 PF13344.6 EAN34320.1 - 0.033 14.3 0.1 0.066 13.3 0.1 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAN34320.1 - 0.15 12.3 0.0 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EAN34321.1 - 7e-39 134.1 1.2 8.9e-39 133.7 1.2 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EAN34321.1 - 2.4e-05 24.0 0.0 0.027 14.0 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EAN34321.1 - 0.00022 21.6 0.0 0.029 14.6 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase LANC_like PF05147.13 EAN34321.1 - 0.046 12.3 0.1 0.065 11.8 0.1 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein HAD_2 PF13419.6 EAN34321.1 - 0.078 13.1 0.3 0.8 9.8 0.0 2.5 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase NAP PF00956.18 EAN34323.1 - 3.9e-12 45.9 2.2 3.4e-05 23.2 0.0 2.7 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.8 EAN34323.1 - 0.00037 20.5 1.2 0.0012 18.9 1.2 1.9 1 1 0 1 1 1 1 C terminal SARAH domain of Mst1 Ins_P5_2-kin PF06090.12 EAN34323.1 - 0.0068 15.9 0.0 0.0079 15.7 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Gal-3-0_sulfotr PF06990.11 EAN34325.1 - 0.099 11.5 0.2 0.12 11.2 0.2 1.2 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase GTP_EFTU PF00009.27 EAN34326.1 - 8.7e-56 188.5 0.1 1.7e-55 187.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EAN34326.1 - 1.1e-16 60.6 0.0 3.5e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 EAN34326.1 - 1e-07 32.0 0.0 2.5e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EAN34326.1 - 1.8e-05 25.1 0.0 4.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAN34326.1 - 0.016 15.3 0.0 0.065 13.3 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 EAN34326.1 - 0.017 14.3 0.1 0.017 14.3 0.1 3.3 3 0 0 3 3 3 0 G-protein alpha subunit EFG_IV PF03764.18 EAN34326.1 - 0.081 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G, domain IV Cir_N PF10197.9 EAN34327.1 - 1.5e-05 25.1 19.1 1.5e-05 25.1 19.1 2.8 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Slu7 PF11708.8 EAN34327.1 - 0.052 13.3 24.4 0.029 14.1 14.6 2.9 2 1 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor Borrelia_P83 PF05262.11 EAN34327.1 - 0.078 11.5 11.2 0.11 11.0 11.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Mem_trans PF03547.18 EAN34327.1 - 0.089 11.2 1.0 0.11 10.9 1.0 1.1 1 0 0 1 1 1 0 Membrane transport protein SID-1_RNA_chan PF13965.6 EAN34327.1 - 0.22 9.9 0.3 0.29 9.5 0.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Phage_Gp23 PF10669.9 EAN34327.1 - 3.4 8.0 19.2 0.14 12.5 12.3 2.2 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF4407 PF14362.6 EAN34327.1 - 9.1 5.5 8.3 12 5.2 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PDCD2_C PF04194.13 EAN34328.1 - 3.5e-29 102.1 4.0 5.3e-28 98.3 0.5 2.2 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain PhnA_Zn_Ribbon PF08274.12 EAN34328.1 - 1.3e-05 25.0 2.8 0.0015 18.4 0.6 3.3 2 1 0 2 2 2 2 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.10 EAN34328.1 - 1 9.5 7.8 11 6.2 0.0 4.1 4 0 0 4 4 4 0 Zinc ribbon domain Cyclin_C PF02984.19 EAN34329.1 - 0.034 14.2 1.3 2 8.5 0.4 2.5 2 0 0 2 2 2 0 Cyclin, C-terminal domain CSTF2_hinge PF14327.6 EAN34329.1 - 0.089 13.3 0.1 0.23 11.9 0.1 1.7 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 DUF4776 PF16003.5 EAN34329.1 - 0.19 10.7 6.1 0.38 9.7 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) WD40 PF00400.32 EAN34330.1 - 1.1e-19 70.4 11.0 0.0039 18.0 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN34330.1 - 2e-10 40.8 0.2 0.028 14.7 0.0 4.6 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EAN34330.1 - 0.012 15.3 0.1 0.036 13.6 0.0 1.9 2 1 0 2 2 2 0 PQQ-like domain Ge1_WD40 PF16529.5 EAN34330.1 - 0.15 10.9 0.8 0.97 8.3 0.3 2.2 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Aminotran_5 PF00266.19 EAN34332.1 - 6.5e-99 331.4 0.0 8e-99 331.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EAN34332.1 - 3.6e-10 39.6 0.0 6.9e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II SHMT PF00464.19 EAN34332.1 - 0.0026 16.4 0.0 0.004 15.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 EAN34332.1 - 0.0043 16.4 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EAN34332.1 - 0.0069 15.7 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase NVEALA PF14055.6 EAN34332.1 - 0.33 11.0 1.5 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 NVEALA protein NAD_kinase PF01513.21 EAN34333.1 - 5.3e-07 29.1 0.0 0.0081 15.4 0.0 2.7 3 0 0 3 3 3 2 ATP-NAD kinase DUF1077 PF06417.12 EAN34333.1 - 0.037 14.0 0.1 0.072 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) DAGK_cat PF00781.24 EAN34333.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain EF1_GNE PF00736.19 EAN34334.1 - 1.1e-28 99.2 1.1 1.1e-28 99.2 1.1 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain DNA_pol3_a_NII PF11490.8 EAN34334.1 - 3.9 7.4 8.9 0.45 10.4 4.4 1.6 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Kinesin PF00225.23 EAN34335.1 - 3.1e-85 286.0 6.7 3.1e-85 286.0 6.7 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EAN34335.1 - 3.3e-20 72.5 0.2 2.5e-19 69.7 0.2 2.7 1 1 0 1 1 1 1 Microtubule binding Fe_hyd_SSU PF02256.17 EAN34335.1 - 0.2 11.7 2.5 11 6.2 0.1 2.8 2 0 0 2 2 2 0 Iron hydrogenase small subunit TFIIA PF03153.13 EAN34336.1 - 8.2e-09 36.0 1.9 9.9e-09 35.7 1.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit UPF0160 PF03690.13 EAN34336.1 - 0.11 12.2 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Fe-S_assembly PF04384.13 EAN34336.1 - 0.3 11.7 0.0 0.3 11.7 0.0 2.4 3 0 0 3 3 3 0 Iron-sulphur cluster assembly Pro_isomerase PF00160.21 EAN34337.1 - 2.1e-38 132.1 0.0 2.3e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Mito_carr PF00153.27 EAN34338.1 - 3.4e-33 113.4 7.7 9e-18 64.0 0.3 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP_bind_1 PF03029.17 EAN34339.1 - 8.8e-70 235.2 1.4 1.5e-69 234.4 1.4 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein SRP54 PF00448.22 EAN34339.1 - 4.2e-05 23.3 0.1 0.00081 19.1 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_31 PF13614.6 EAN34339.1 - 5.4e-05 23.2 0.5 0.00013 21.9 0.5 1.5 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 EAN34339.1 - 0.00064 19.2 0.1 0.0012 18.4 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein MeaB PF03308.16 EAN34339.1 - 0.0008 18.5 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 EAN34339.1 - 0.001 18.9 0.1 0.0016 18.3 0.1 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 EAN34339.1 - 0.0014 18.6 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EAN34339.1 - 0.0019 18.4 0.0 0.0032 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 EAN34339.1 - 0.0037 17.2 0.1 0.0094 15.8 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 EAN34339.1 - 0.0041 17.1 0.0 0.006 16.5 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 EAN34339.1 - 0.0046 16.7 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EAN34339.1 - 0.0069 15.9 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 NTPase_1 PF03266.15 EAN34339.1 - 0.007 16.3 0.3 0.083 12.8 0.3 2.2 1 1 0 1 1 1 1 NTPase AAA_16 PF13191.6 EAN34339.1 - 0.0078 16.6 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 EAN34339.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 EAN34339.1 - 0.013 15.0 0.1 0.029 13.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EAN34339.1 - 0.017 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 EAN34339.1 - 0.02 15.2 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EAN34339.1 - 0.02 14.5 0.3 0.083 12.5 0.3 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Sec34 PF04136.15 EAN34339.1 - 0.027 14.4 1.5 0.17 11.8 0.6 2.3 1 1 1 2 2 2 0 Sec34-like family PIF1 PF05970.14 EAN34339.1 - 0.029 13.6 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF87 PF01935.17 EAN34339.1 - 0.044 13.9 0.1 0.15 12.2 0.0 1.8 1 1 1 2 2 2 0 Helicase HerA, central domain MipZ PF09140.11 EAN34339.1 - 0.048 12.9 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ AAA_14 PF13173.6 EAN34339.1 - 0.049 13.7 0.2 0.14 12.2 0.1 1.9 1 1 1 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EAN34339.1 - 0.054 13.2 0.2 0.17 11.6 0.1 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Roc PF08477.13 EAN34339.1 - 0.058 13.6 0.1 0.16 12.2 0.1 1.9 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAN34339.1 - 0.065 12.8 0.3 4.1 7.0 0.1 2.2 1 1 1 2 2 2 0 Ras family DUF1987 PF09345.10 EAN34339.1 - 0.086 12.5 1.4 0.35 10.5 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1987) AAA_19 PF13245.6 EAN34339.1 - 0.088 13.1 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAN34339.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EAN34339.1 - 0.15 11.3 0.0 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family PseudoU_synth_1 PF01416.20 EAN34340.1 - 4.7e-12 46.3 0.0 2.1e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 EAN34340.1 - 0.063 13.1 0.1 0.15 11.9 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Pro_isomerase PF00160.21 EAN34341.1 - 5.8e-38 130.6 0.0 8.1e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ArfGap PF01412.18 EAN34342.1 - 1.9e-28 98.9 0.0 4e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3899 PF13038.6 EAN34344.1 - 2.4 8.7 4.8 2.5 8.7 0.6 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF3899) Myosin_head PF00063.21 EAN34345.1 - 1.8e-176 588.3 20.6 2.8e-176 587.7 20.6 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) RCC1 PF00415.18 EAN34345.1 - 1.8e-21 76.5 6.1 6.9e-10 39.4 0.2 5.6 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAN34345.1 - 6.6e-16 57.6 15.3 3e-09 36.4 0.3 4.8 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 EAN34345.1 - 8.6e-13 46.9 15.3 0.0015 18.1 0.0 5.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif Myosin_N PF02736.19 EAN34345.1 - 0.0087 15.9 3.5 0.022 14.6 3.5 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Hit1_C PF18268.1 EAN34345.1 - 0.013 15.6 0.7 5.8 7.1 0.4 2.9 2 0 0 2 2 2 0 Hit1 C-terminal AAA_22 PF13401.6 EAN34345.1 - 0.022 15.0 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAN34345.1 - 0.16 12.3 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PqiA PF04403.13 EAN34346.1 - 7.2e-09 35.7 13.5 5.3e-05 23.1 4.6 3.1 3 0 0 3 3 3 2 Paraquat-inducible protein A zf-C3HC4_3 PF13920.6 EAN34348.1 - 1.1e-13 50.8 11.6 2.1e-13 49.9 11.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAN34348.1 - 1.5e-08 34.4 11.9 1.7e-07 31.0 12.6 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EAN34348.1 - 2.8e-05 24.3 12.8 6.5e-05 23.2 12.8 1.6 1 0 0 1 1 1 1 Ring finger domain DUF1644 PF07800.12 EAN34348.1 - 0.011 15.8 7.8 0.19 11.8 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_5 PF14634.6 EAN34348.1 - 0.013 15.4 11.6 0.013 15.4 11.6 1.7 2 0 0 2 2 2 0 zinc-RING finger domain Rubredoxin_2 PF18073.1 EAN34348.1 - 0.083 12.6 3.1 0.26 11.0 0.9 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-C3HC4_2 PF13923.6 EAN34348.1 - 0.12 12.2 12.9 0.21 11.5 12.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAN34348.1 - 0.2 11.4 7.4 0.11 12.2 4.3 2.3 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 EAN34348.1 - 1.5 8.9 10.7 1.3 9.1 8.5 2.1 1 1 1 2 2 2 0 RING-type zinc-finger Minor_tail_Z PF06763.11 EAN34349.1 - 0.81 9.4 2.2 1.6 8.5 0.2 2.1 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) Cpn60_TCP1 PF00118.24 EAN34351.1 - 2.1e-155 518.1 10.0 2.3e-155 517.9 10.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RPAP2_Rtr1 PF04181.13 EAN34352.1 - 1.4e-16 60.6 3.6 3.6e-16 59.2 3.6 1.8 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_3 PF08239.11 EAN34355.1 - 0.0006 20.0 0.9 0.0012 19.1 0.9 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain PL48 PF15903.5 EAN34356.1 - 0.0099 14.9 0.1 0.02 13.9 0.1 1.4 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 Ribosomal_L1 PF00687.21 EAN34357.1 - 5.8e-18 65.4 3.7 6.4e-18 65.2 2.5 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family LZ3wCH PF18517.1 EAN34357.1 - 0.006 16.7 3.4 0.006 16.7 3.4 2.4 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Swi5 PF07061.11 EAN34357.1 - 0.022 14.9 1.0 0.06 13.4 1.0 1.8 1 0 0 1 1 1 0 Swi5 PFK PF00365.20 EAN34357.1 - 0.082 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Phosphofructokinase PhetRS_B1 PF18262.1 EAN34357.1 - 0.15 12.3 1.2 0.51 10.6 1.2 2.0 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain WD40 PF00400.32 EAN34358.1 - 2.7e-25 88.1 10.3 0.00021 22.0 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAN34358.1 - 7.9e-13 48.5 0.0 0.013 15.8 0.3 6.1 2 2 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAN34358.1 - 1.9e-07 31.2 3.7 0.00024 21.0 0.1 3.9 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAN34358.1 - 0.015 14.3 0.0 4.7 6.1 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sarcoglycan_1 PF04790.13 EAN34358.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein DUF2480 PF10652.9 EAN34358.1 - 0.14 12.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2480) Vps16_N PF04841.13 EAN34359.1 - 7.3e-14 51.3 0.3 8.4e-06 24.8 0.2 2.3 2 0 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.12 EAN34359.1 - 9.8e-13 47.8 2.7 2.5e-06 26.7 0.1 2.5 2 0 0 2 2 2 2 Vps16, C-terminal region Peptidase_M41 PF01434.18 EAN34360.1 - 6.3e-53 179.5 0.1 1.2e-52 178.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EAN34360.1 - 8.5e-43 145.9 0.0 3.3e-42 144.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAN34360.1 - 4e-12 45.7 0.0 9.8e-12 44.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EAN34360.1 - 8.6e-07 28.8 0.0 2.7e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EAN34360.1 - 2.1e-05 23.9 0.0 4.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EAN34360.1 - 4e-05 23.6 0.0 0.00014 21.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAN34360.1 - 5.9e-05 23.5 0.2 0.003 18.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAN34360.1 - 8.1e-05 22.9 0.4 0.0082 16.4 0.1 3.1 1 1 2 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EAN34360.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EAN34360.1 - 0.0016 17.8 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EAN34360.1 - 0.0016 18.7 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EAN34360.1 - 0.0022 18.1 0.0 0.0071 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EAN34360.1 - 0.0026 18.0 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EAN34360.1 - 0.0057 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EAN34360.1 - 0.0096 16.3 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EAN34360.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAN34360.1 - 0.012 16.2 0.2 0.044 14.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 EAN34360.1 - 0.026 13.7 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EAN34360.1 - 0.043 13.1 0.1 0.1 11.9 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 EAN34360.1 - 0.052 13.1 0.1 0.12 11.9 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EAN34360.1 - 0.058 13.4 0.1 0.36 10.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 EAN34360.1 - 0.094 12.3 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAN34360.1 - 0.1 12.5 0.4 0.25 11.2 0.4 1.6 1 0 0 1 1 1 0 NACHT domain IPT PF01745.16 EAN34360.1 - 0.15 11.4 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase HK PF02110.15 EAN34362.1 - 2.3e-05 23.9 0.0 2.6e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family DNA_gyraseB PF00204.25 EAN34363.1 - 1.2e-44 151.9 0.6 2.3e-44 150.9 0.6 1.6 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 EAN34363.1 - 1.1e-23 83.1 0.1 2.3e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus Toprim PF01751.22 EAN34363.1 - 9.1e-18 64.4 0.1 1.2e-16 60.7 0.0 3.0 3 0 0 3 3 3 1 Toprim domain HATPase_c PF02518.26 EAN34363.1 - 3.4e-14 53.3 0.1 4.1e-13 49.8 0.0 2.9 3 1 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ACDC PF14733.6 EAN34364.1 - 1.9e-15 57.0 0.4 1.9e-15 57.0 0.4 2.0 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.20 EAN34364.1 - 9.5e-11 41.8 1.8 2e-10 40.7 1.8 1.6 1 0 0 1 1 1 1 AP2 domain Ribosomal_L23 PF00276.20 EAN34365.1 - 2.8e-13 50.0 0.1 6.3e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 AsnC_trans_reg PF01037.21 EAN34366.1 - 0.079 12.9 0.0 0.77 9.8 0.0 2.4 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain DUF5344 PF17279.2 EAN34366.1 - 1.1 9.8 5.8 2 9.0 4.3 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5344) PLDc_2 PF13091.6 EAN34368.1 - 6e-15 55.3 0.0 9.5e-07 28.8 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EAN34368.1 - 0.14 12.4 8.3 0.38 11.0 0.1 3.9 3 1 0 3 3 3 0 Phospholipase D Active site motif HeLo PF14479.6 EAN34369.1 - 1.2 9.0 4.9 0.33 10.7 1.3 1.7 1 1 0 2 2 2 0 Prion-inhibition and propagation SNF2_N PF00176.23 EAN34370.1 - 1.3e-64 218.1 1.2 1.3e-64 218.1 1.2 2.8 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAN34370.1 - 2.6e-20 72.8 0.2 7.8e-19 68.1 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DicB PF05358.11 EAN34370.1 - 0.047 13.9 1.4 0.23 11.6 0.2 2.9 2 1 0 2 2 2 0 DicB protein OMPdecase PF00215.24 EAN34371.1 - 6.4e-18 65.2 0.0 1.2e-17 64.3 0.0 1.6 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF4240 PF14024.6 EAN34371.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) PRORP PF16953.5 EAN34372.1 - 1.2e-13 51.2 0.4 3e-09 36.8 0.2 2.4 2 0 0 2 2 2 2 Protein-only RNase P RNase_Zc3h12a PF11977.8 EAN34372.1 - 1.6e-09 37.7 0.2 9e-08 32.0 0.0 2.6 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain UFD1 PF03152.14 EAN34373.1 - 0.026 14.0 0.0 0.085 12.3 0.0 1.8 2 1 0 2 2 2 0 Ubiquitin fusion degradation protein UFD1 UAA PF08449.11 EAN34374.1 - 3.2e-40 138.2 24.3 2.9e-39 135.1 17.9 2.0 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 EAN34374.1 - 1.6e-10 41.3 11.3 1.6e-10 41.3 11.3 3.1 3 1 0 3 3 3 2 EamA-like transporter family OppC_N PF12911.7 EAN34374.1 - 0.3 11.1 2.2 6.2 6.9 0.0 3.6 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C ubiquitin PF00240.23 EAN34375.1 - 2.4e-21 75.3 0.0 5e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAN34375.1 - 1.1e-10 41.1 0.0 1.9e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 EAN34375.1 - 2e-07 30.8 0.1 5.3e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 EAN34375.1 - 0.0034 17.4 0.1 0.014 15.4 0.1 2.0 2 0 0 2 2 2 1 HOIP UBA domain pair DUF2407 PF10302.9 EAN34375.1 - 0.0077 16.8 0.0 0.024 15.2 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain STI1 PF17830.1 EAN34375.1 - 0.011 15.6 4.4 0.19 11.7 0.0 3.1 2 1 0 2 2 2 0 STI1 domain Rad60-SLD_2 PF13881.6 EAN34375.1 - 0.02 15.0 0.2 0.067 13.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 EAN34375.1 - 0.038 13.7 0.9 0.19 11.5 0.0 2.4 2 0 0 2 2 2 0 CUE domain Ubiquitin_2 PF14560.6 EAN34375.1 - 0.087 13.3 0.0 0.25 11.8 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain UBA_5 PF16577.5 EAN34375.1 - 0.092 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 UBA domain FliT PF05400.13 EAN34375.1 - 2.8 8.8 5.1 0.57 11.0 0.2 2.4 3 1 0 3 3 3 0 Flagellar protein FliT TPR_2 PF07719.17 EAN34376.1 - 1.6e-07 30.9 0.0 0.0048 16.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAN34376.1 - 8.4e-07 28.6 0.1 0.015 15.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAN34376.1 - 8.6e-06 26.2 0.1 2.6e-05 24.6 0.1 1.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAN34376.1 - 0.00047 20.4 0.1 0.054 13.8 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAN34376.1 - 0.0017 18.4 0.5 0.016 15.3 0.0 2.1 1 1 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 EAN34376.1 - 0.0053 17.5 0.0 0.041 14.7 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAN34376.1 - 0.0056 16.8 0.2 0.46 10.8 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Med9 PF07544.13 EAN34376.1 - 0.028 14.5 1.6 0.62 10.2 1.5 2.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TPR_6 PF13174.6 EAN34376.1 - 0.032 14.9 0.0 0.98 10.2 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat EF-G-binding_N PF07299.11 EAN34376.1 - 0.049 14.2 3.8 0.2 12.2 0.9 2.2 1 1 1 2 2 2 0 Elongation factor G-binding protein, N-terminal Laminin_II PF06009.12 EAN34376.1 - 0.066 13.2 1.9 0.11 12.5 1.9 1.3 1 1 0 1 1 1 0 Laminin Domain II AP2 PF00847.20 EAN34377.1 - 1.1e-07 32.0 1.9 3.8e-06 27.0 0.2 2.5 2 0 0 2 2 2 1 AP2 domain CNDH2_C PF16858.5 EAN34377.1 - 0.0053 16.7 0.5 0.0053 16.7 0.5 2.2 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Iron_permease PF04120.12 EAN34377.1 - 0.96 9.2 3.9 0.28 10.9 0.7 1.7 2 0 0 2 2 2 0 Low affinity iron permease DSPc PF00782.20 EAN34378.1 - 1.2e-08 34.9 0.0 1.9e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAN34378.1 - 0.00078 19.1 0.0 0.00096 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EAN34378.1 - 0.0015 18.2 0.3 0.0053 16.4 0.2 1.8 1 1 1 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Acylphosphatase PF00708.18 EAN34379.1 - 4e-23 81.6 0.1 4.5e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase DUF1433 PF07252.11 EAN34379.1 - 0.057 13.7 0.2 0.094 13.0 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1433) DNA_ligase_A_M PF01068.21 EAN34380.1 - 0.00067 19.4 0.1 0.0015 18.2 0.1 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain mRNA_cap_enzyme PF01331.19 EAN34380.1 - 0.0011 18.9 0.2 0.0036 17.2 0.2 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain STAR_dimer PF16544.5 EAN34380.1 - 0.0033 17.0 0.0 0.0095 15.5 0.0 1.8 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein Exo_endo_phos PF03372.23 EAN34381.1 - 0.028 13.9 0.0 0.1 12.1 0.0 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF3799 PF12684.7 EAN34383.1 - 0.056 13.2 0.4 0.072 12.8 0.4 1.2 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) Ribosomal_L18_c PF14204.6 EAN34383.1 - 0.23 12.4 1.5 1.2 10.1 0.2 2.2 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Pcc1 PF09341.10 EAN34384.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription factor Pcc1 GPI2 PF06432.11 EAN34385.1 - 1.6e-09 37.6 6.5 1.9e-09 37.4 6.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Pex24p PF06398.11 EAN34385.1 - 0.21 10.5 8.4 0.24 10.3 8.4 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DEAD PF00270.29 EAN34386.1 - 2.4e-16 60.0 0.0 2.8e-14 53.3 0.0 2.8 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAN34386.1 - 8.4e-13 48.6 1.4 4.4e-12 46.3 1.4 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain APS_kinase PF01583.20 EAN34386.1 - 0.12 12.3 0.0 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase HTH_45 PF14947.6 EAN34386.1 - 9.5 6.3 8.0 10 6.2 0.5 3.4 3 0 0 3 3 3 0 Winged helix-turn-helix Syja_N PF02383.18 EAN34387.1 - 1.4e-60 205.3 4.7 2.5e-60 204.5 4.7 1.4 1 0 0 1 1 1 1 SacI homology domain Synaphin PF05835.12 EAN34387.1 - 0.031 14.6 0.1 0.059 13.6 0.1 1.4 1 0 0 1 1 1 0 Synaphin protein Peptidase_M18 PF02127.15 EAN34388.1 - 6.4e-122 407.4 0.0 7.4e-122 407.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EAN34388.1 - 0.0006 18.9 0.0 0.028 13.4 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase CLPTM1 PF05602.12 EAN34389.1 - 3.1e-66 224.2 26.9 1.7e-52 178.9 13.1 2.3 2 0 0 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EAN34389.1 - 6.7e-05 22.6 10.9 0.019 14.8 0.2 3.6 4 0 0 4 4 4 2 PQ loop repeat RTA1 PF04479.13 EAN34389.1 - 1.4 8.5 8.1 2.5 7.6 0.5 2.9 3 0 0 3 3 3 0 RTA1 like protein DnaJ PF00226.31 EAN34390.1 - 1.9e-21 76.0 1.4 1.9e-21 76.0 1.4 2.1 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.11 EAN34390.1 - 5.1e-08 33.1 3.4 1.5e-07 31.6 3.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 EAN34390.1 - 0.074 13.2 0.0 0.39 10.9 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1771 PF08590.10 EAN34390.1 - 0.36 11.2 2.6 0.23 11.8 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) stn_TNFRSF12A PF12191.8 EAN34391.1 - 0.011 15.9 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain RAP PF08373.10 EAN34392.1 - 0.017 15.2 0.2 0.017 15.2 0.2 2.8 3 1 0 3 3 3 0 RAP domain ARS2 PF04959.13 EAN34392.1 - 0.023 15.1 0.6 0.032 14.6 0.6 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 PHtD_u1 PF16645.5 EAN34393.1 - 0.62 10.5 7.9 0.21 12.0 4.9 1.9 2 0 0 2 2 2 0 Unstructured region on Pneumococcal histidine triad protein Sod_Fe_C PF02777.18 EAN34394.1 - 1.9e-37 127.5 3.0 2.5e-37 127.1 0.0 2.3 2 1 1 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EAN34394.1 - 1.8e-29 102.0 0.8 1.8e-29 102.0 0.8 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DDHD PF02862.17 EAN34395.1 - 4e-37 128.6 0.6 7.4e-37 127.7 0.6 1.5 1 0 0 1 1 1 1 DDHD domain DUF676 PF05057.14 EAN34395.1 - 0.022 14.3 0.6 0.12 11.9 0.0 2.3 3 0 0 3 3 3 0 Putative serine esterase (DUF676) RNA_pol_Rpb1_6 PF04992.14 EAN34395.1 - 0.074 12.9 0.0 0.074 12.9 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb1, domain 6 Abhydrolase_2 PF02230.16 EAN34395.1 - 0.15 11.9 0.1 3.1 7.5 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Lipase_2 PF01674.18 EAN34395.1 - 0.85 9.1 4.5 0.86 9.1 0.0 2.6 3 0 0 3 3 3 0 Lipase (class 2) AAA PF00004.29 EAN34396.1 - 1.5e-82 274.6 0.2 1.1e-42 145.6 0.0 3.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAN34396.1 - 2e-21 75.5 0.0 8.7e-12 44.7 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 EAN34396.1 - 1.4e-14 54.3 0.0 1.9e-05 24.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAN34396.1 - 6.2e-13 49.5 0.7 0.001 19.4 0.0 4.3 2 2 2 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 EAN34396.1 - 1.6e-12 47.4 0.1 2.4e-05 24.1 0.0 3.4 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAN34396.1 - 1.3e-10 41.7 0.2 0.00076 19.8 0.0 3.7 2 1 1 3 3 3 2 AAA domain AAA_2 PF07724.14 EAN34396.1 - 3e-10 40.5 0.0 0.0026 17.9 0.0 3.9 4 0 0 4 4 4 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EAN34396.1 - 2.5e-09 36.8 0.0 0.00014 21.2 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 EAN34396.1 - 8.7e-09 36.0 0.0 0.0093 16.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EAN34396.1 - 1.8e-08 34.7 0.0 0.0003 21.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 EAN34396.1 - 7.8e-08 32.2 0.1 0.091 12.5 0.1 3.7 2 2 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EAN34396.1 - 1.4e-07 31.4 0.0 0.022 14.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_3 PF07726.11 EAN34396.1 - 1.6e-07 31.3 0.0 0.00087 19.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EAN34396.1 - 2.2e-07 31.2 0.1 0.0081 16.5 0.0 3.4 3 1 0 3 3 3 2 RNA helicase AAA_14 PF13173.6 EAN34396.1 - 2.7e-07 30.7 0.0 0.0087 16.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 EAN34396.1 - 2.7e-07 31.2 0.1 0.02 15.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Mg_chelatase PF01078.21 EAN34396.1 - 1.1e-06 28.2 1.9 0.02 14.3 0.1 2.9 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EAN34396.1 - 1.5e-06 28.6 0.1 0.008 16.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EAN34396.1 - 1.9e-05 24.6 0.1 0.28 11.1 0.0 2.8 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 EAN34396.1 - 2.5e-05 24.3 1.3 0.4 10.6 0.0 4.3 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EAN34396.1 - 3e-05 23.4 0.0 0.19 11.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TsaE PF02367.17 EAN34396.1 - 3.2e-05 23.9 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Vps4_C PF09336.10 EAN34396.1 - 4e-05 23.5 0.1 0.00035 20.5 0.1 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain NB-ARC PF00931.22 EAN34396.1 - 4.2e-05 22.9 0.0 0.078 12.2 0.0 2.9 2 1 0 2 2 2 2 NB-ARC domain AAA_17 PF13207.6 EAN34396.1 - 5.6e-05 23.6 0.2 0.32 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EAN34396.1 - 7.1e-05 22.5 1.0 1.5 8.3 0.0 3.5 3 1 1 4 4 3 1 AAA domain Parvo_NS1 PF01057.17 EAN34396.1 - 0.0001 21.5 0.1 0.47 9.5 0.0 2.5 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 EAN34396.1 - 0.00014 21.6 0.0 0.19 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EAN34396.1 - 0.00023 20.7 0.0 0.15 11.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_11 PF13086.6 EAN34396.1 - 0.00037 20.4 0.5 0.22 11.3 0.0 2.9 4 0 0 4 4 3 1 AAA domain CPT PF07931.12 EAN34396.1 - 0.00065 19.6 0.0 0.095 12.5 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.13 EAN34396.1 - 0.00065 18.9 0.0 0.45 9.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EAN34396.1 - 0.00094 19.1 2.1 0.46 10.4 0.0 3.6 4 0 0 4 4 4 1 NTPase SKI PF01202.22 EAN34396.1 - 0.0015 18.6 0.1 4 7.5 0.0 3.2 3 0 0 3 3 3 0 Shikimate kinase Viral_helicase1 PF01443.18 EAN34396.1 - 0.0016 18.3 0.0 1 9.0 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 EAN34396.1 - 0.0076 16.0 0.0 2.8 7.7 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 EAN34396.1 - 0.012 16.0 0.8 5.5 7.3 0.3 3.0 3 1 0 3 3 2 0 AAA domain Sigma54_activ_2 PF14532.6 EAN34396.1 - 0.018 15.2 0.0 4.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SSE PF00437.20 EAN34396.1 - 0.021 13.9 0.0 4 6.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 EAN34396.1 - 0.023 14.1 0.6 9.4 5.6 0.0 3.1 2 1 0 2 2 2 0 PhoH-like protein TniB PF05621.11 EAN34396.1 - 0.024 14.1 1.2 11 5.3 0.0 4.1 4 0 0 4 4 4 0 Bacterial TniB protein Bac_DnaA PF00308.18 EAN34396.1 - 0.024 14.5 0.8 2 8.2 0.0 2.9 3 0 0 3 3 2 0 Bacterial dnaA protein Nucleolin_bd PF16725.5 EAN34396.1 - 0.024 14.3 0.0 0.063 12.9 0.0 1.7 1 0 0 1 1 1 0 Nucleolin binding domain AAA_29 PF13555.6 EAN34396.1 - 0.026 14.3 0.1 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 EAN34396.1 - 0.033 14.1 6.4 1.2 9.0 0.1 4.3 3 2 2 5 5 4 0 Rad17 P-loop domain DUF2075 PF09848.9 EAN34396.1 - 0.038 13.2 0.0 5 6.3 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EAN34396.1 - 0.039 13.7 0.1 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EAN34396.1 - 0.043 13.3 0.1 11 5.3 0.0 3.3 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Hydin_ADK PF17213.3 EAN34396.1 - 0.045 14.0 0.2 4.4 7.5 0.0 2.6 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain Zot PF05707.12 EAN34396.1 - 0.061 13.0 0.0 1.5 8.5 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 EAN34396.1 - 0.07 12.9 0.1 9.8 5.8 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase ATPase PF06745.13 EAN34396.1 - 0.087 12.2 4.7 2.2 7.6 0.0 3.6 4 1 0 4 4 2 0 KaiC P5-ATPase PF12409.8 EAN34396.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 P5-type ATPase cation transporter AAA_23 PF13476.6 EAN34396.1 - 0.5 10.8 7.8 7.4 7.0 0.0 3.5 2 1 0 3 3 2 0 AAA domain Helicase_C PF00271.31 EAN34398.1 - 6e-05 23.3 0.5 6e-05 23.3 0.5 3.6 3 1 1 4 4 4 1 Helicase conserved C-terminal domain GATase PF00117.28 EAN34400.1 - 1.8e-13 50.7 0.0 1.1e-11 44.9 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EAN34400.1 - 0.00027 20.8 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase C26 MFS_1 PF07690.16 EAN34401.1 - 1.6e-10 40.5 10.5 1.6e-10 40.5 10.5 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Helicase_C PF00271.31 EAN34403.1 - 2e-13 50.7 0.0 6.3e-13 49.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 EAN34403.1 - 4.2e-11 42.6 0.1 9.6e-11 41.4 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal TSR PF18487.1 EAN34403.1 - 5.7 7.2 7.4 1.4 9.2 0.5 2.9 3 0 0 3 3 3 0 Thrombospondin type 1 repeat SF1-HH PF16275.5 EAN34404.1 - 6.7e-29 100.5 0.0 6.7e-29 100.5 0.0 2.6 3 0 0 3 3 3 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 EAN34404.1 - 1.5e-07 31.2 0.1 3.2e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 EAN34404.1 - 1.7e-06 27.8 7.2 0.012 15.7 0.1 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 EAN34404.1 - 0.00034 20.5 2.5 0.091 12.7 0.4 2.4 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EAN34404.1 - 0.027 14.2 4.7 1.6 8.5 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle FmdA_AmdA PF03069.15 EAN34404.1 - 0.12 11.2 0.9 0.17 10.7 0.9 1.2 1 0 0 1 1 1 0 Acetamidase/Formamidase family zf-CCHC_6 PF15288.6 EAN34404.1 - 1 9.3 7.6 9.3 6.2 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 EAN34405.1 - 1.9e-37 129.1 0.0 3e-28 98.9 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAN34405.1 - 5.2e-21 75.1 0.0 1.5e-15 57.2 0.1 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EAN34405.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EAN34405.1 - 0.041 13.2 0.0 0.12 11.7 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sde2_N_Ubi PF13019.6 EAN34405.1 - 0.074 12.9 0.7 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain DUF4381 PF14316.6 EAN34405.1 - 0.13 12.5 1.0 0.29 11.4 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zf-U1 PF06220.12 EAN34406.1 - 5.6e-19 67.6 1.1 7.9e-19 67.2 1.1 1.2 1 0 0 1 1 1 1 U1 zinc finger Tom22 PF04281.13 EAN34407.1 - 0.00044 20.1 0.1 0.0005 19.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CDP-OH_P_transf PF01066.21 EAN34409.1 - 2.2e-08 34.7 0.1 2.2e-08 34.7 0.1 3.7 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Spo12 PF05032.12 EAN34409.1 - 0.25 11.3 2.9 0.13 12.2 0.6 1.7 2 0 0 2 2 2 0 Spo12 family SANT_DAMP1_like PF16282.5 EAN34411.1 - 5e-23 81.1 2.2 5e-23 81.1 2.2 2.4 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EAN34411.1 - 0.45 10.8 3.6 0.25 11.6 0.3 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain UPF0086 PF01868.16 EAN34412.1 - 1.5e-21 76.1 0.1 2.6e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Chlorosome_CsmC PF11098.8 EAN34412.1 - 0.065 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C HECT PF00632.25 EAN34413.1 - 4.2e-42 144.7 0.0 1.2e-41 143.2 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 EAN34413.1 - 3.1e-08 34.1 0.1 1.5e-07 31.9 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAN34413.1 - 5.7e-05 23.6 0.4 1.2 9.9 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAN34413.1 - 0.00021 21.5 2.9 0.58 10.9 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EAN34413.1 - 0.00059 20.2 1.0 0.12 12.9 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAN34413.1 - 0.003 17.8 0.2 0.57 10.6 0.0 3.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) SPRY PF00622.28 EAN34413.1 - 0.13 12.4 0.4 5.5 7.1 0.0 2.6 2 0 0 2 2 2 0 SPRY domain EGF PF00008.27 EAN34416.1 - 0.0086 16.4 14.3 0.012 15.8 2.6 2.7 2 1 0 2 2 2 2 EGF-like domain hEGF PF12661.7 EAN34416.1 - 0.02 15.5 2.1 0.22 12.2 2.1 2.9 1 1 0 1 1 1 0 Human growth factor-like EGF EB PF01683.18 EAN34416.1 - 0.021 15.1 5.7 0.021 15.1 5.7 2.2 1 1 1 2 2 2 0 EB module NAD_binding_1 PF00175.21 EAN34418.1 - 2.7e-15 56.9 0.0 5.7e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EAN34418.1 - 1.5e-06 28.4 0.0 3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EAN34418.1 - 0.00022 21.4 0.6 0.0018 18.4 0.1 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_1 PF00667.20 EAN34418.1 - 0.026 14.1 0.0 0.37 10.3 0.0 2.1 1 1 0 2 2 2 0 FAD binding domain DUF1168 PF06658.12 EAN34419.1 - 1.3e-20 73.6 15.6 2.3e-20 72.8 15.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) Trypan_PARP PF05887.11 EAN34419.1 - 0.13 12.3 6.8 0.23 11.4 6.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Exonuc_VII_L PF02601.15 EAN34419.1 - 0.18 11.3 6.7 0.21 11.1 6.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5523 PF17661.1 EAN34419.1 - 0.3 10.7 19.5 0.38 10.4 19.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Ldh_1_C PF02866.18 EAN34420.1 - 1.9e-29 102.8 0.0 4.4e-29 101.5 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EAN34420.1 - 2.4e-29 102.2 1.0 3.7e-29 101.6 1.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 EAN34420.1 - 1.1e-06 28.4 0.1 2.5e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Glyco_hydro_3_C PF01915.22 EAN34420.1 - 0.052 13.5 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Hydantoinase_A PF01968.18 EAN34420.1 - 0.067 12.4 0.5 1.4 8.1 0.0 2.2 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase DUF2179 PF10035.9 EAN34420.1 - 0.13 12.0 1.1 0.98 9.2 0.4 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) Prp18 PF02840.15 EAN34421.1 - 4.4e-55 185.7 1.9 4.4e-55 185.7 1.9 2.1 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EAN34421.1 - 1.2e-10 40.7 0.8 2.4e-10 39.8 0.8 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like NARP1 PF12569.8 EAN34422.1 - 3.5e-31 108.7 7.5 1.1e-15 57.6 0.3 3.5 3 0 0 3 3 3 3 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EAN34422.1 - 2.5e-14 52.2 0.5 4.9e-05 23.1 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAN34422.1 - 1.5e-10 40.4 4.4 5.4e-07 29.2 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAN34422.1 - 8.5e-08 32.4 0.0 1.9 9.5 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAN34422.1 - 1.2e-07 31.9 0.4 0.51 10.7 0.1 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAN34422.1 - 2.3e-07 30.5 0.2 0.047 13.9 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAN34422.1 - 1.6e-05 25.0 7.9 0.077 13.2 1.5 4.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EAN34422.1 - 6.3e-05 23.4 0.3 8.6 7.2 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAN34422.1 - 0.00073 20.0 0.0 38 4.9 0.0 4.9 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAN34422.1 - 0.0015 18.4 0.0 0.31 11.2 0.0 3.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAN34422.1 - 0.0048 17.2 0.5 20 5.8 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAN34422.1 - 0.0063 16.2 0.0 15 5.4 0.0 3.6 3 0 0 3 3 3 0 TPR repeat Fis1_TPR_C PF14853.6 EAN34422.1 - 0.011 15.8 0.2 10 6.3 0.0 3.7 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 EAN34422.1 - 0.083 12.1 0.0 10 5.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EAN34422.1 - 0.3 11.2 3.8 2.4 8.3 0.0 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 FAINT PF04385.15 EAN34423.1 - 9.4e-06 25.6 5.1 0.017 15.2 0.0 4.1 4 0 0 4 4 4 2 Domain of unknown function, DUF529 Hydrolase_4 PF12146.8 EAN34423.1 - 2.7e-05 23.6 0.1 0.00022 20.6 0.0 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EAN34423.1 - 0.038 13.8 0.0 0.34 10.7 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EAN34423.1 - 0.053 14.1 0.0 0.23 12.0 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EAN34424.1 - 0.2 11.8 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 TAP-like protein zf-B_box PF00643.24 EAN34425.1 - 0.0027 17.8 4.2 0.0027 17.8 4.2 3.2 4 0 0 4 4 4 2 B-box zinc finger MLD PF11647.8 EAN34425.1 - 0.02 15.2 2.0 0.063 13.6 2.0 1.8 1 0 0 1 1 1 0 Membrane Localization Domain Siva PF05458.12 EAN34425.1 - 0.051 13.2 3.4 0.14 11.8 3.4 1.7 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF1652 PF07865.11 EAN34425.1 - 0.12 12.3 0.5 0.26 11.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) CEBP_ZZ PF16366.5 EAN34425.1 - 0.29 11.4 7.2 0.85 9.9 7.2 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain GTP_EFTU PF00009.27 EAN34426.1 - 5e-13 49.0 0.1 1.1e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EAN34426.1 - 1.3e-10 41.3 0.0 3.7e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 CKS PF01111.19 EAN34427.1 - 1.3e-20 73.4 0.0 2.7e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit CWC25 PF12542.8 EAN34428.1 - 7.7e-10 39.6 0.1 7.7e-10 39.6 0.1 3.4 3 1 0 3 3 3 1 Pre-mRNA splicing factor RCC1_2 PF13540.6 EAN34429.1 - 3.5e-06 26.7 0.3 0.00035 20.3 0.1 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EAN34429.1 - 0.00045 20.8 0.4 0.048 14.3 0.0 3.7 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat SBBP PF06739.11 EAN34429.1 - 0.0063 16.5 0.2 3 7.9 0.0 2.5 2 0 0 2 2 2 2 Beta-propeller repeat Lip_prot_lig_C PF10437.9 EAN34430.1 - 5e-09 36.0 0.1 3.4e-08 33.4 0.0 2.4 3 0 0 3 3 3 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.19 EAN34430.1 - 1.6e-07 31.3 0.0 5e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF5601 PF18151.1 EAN34430.1 - 0.22 11.9 1.6 0.84 10.0 0.1 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5601) Pinin_SDK_memA PF04696.13 EAN34431.1 - 1.9e-19 70.0 7.9 1.9e-19 70.0 7.9 1.8 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region TBCC PF07986.12 EAN34432.1 - 3.4e-30 104.3 0.3 6.4e-30 103.4 0.3 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C EMP24_GP25L PF01105.24 EAN34433.1 - 2.2e-31 109.2 1.2 2.7e-31 108.9 1.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribonuc_red_sm PF00268.21 EAN34434.1 - 1.1e-60 205.4 7.4 1.1e-59 202.2 7.4 1.9 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain RisS_PPD PF16524.5 EAN34434.1 - 0.15 12.3 1.1 0.44 10.8 0.1 2.3 3 1 1 4 4 4 0 Periplasmic domain of Sensor histidine kinase RisS AIP3 PF03915.13 EAN34436.1 - 0.0097 15.0 0.8 0.71 8.9 0.4 2.0 2 0 0 2 2 2 2 Actin interacting protein 3 Exo_endo_phos PF03372.23 EAN34437.1 - 3.1e-12 46.5 0.0 4.2e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PDEase_I PF00233.19 EAN34438.1 - 2.2e-64 217.4 0.3 4.1e-64 216.6 0.3 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EAN34438.1 - 0.21 11.8 0.0 0.49 10.6 0.0 1.5 1 0 0 1 1 1 0 HD domain RRM_1 PF00076.22 EAN34439.1 - 6.7e-36 121.9 0.1 1.1e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 EAN34439.1 - 6.6e-10 38.9 2.7 1.3e-09 37.9 2.7 1.5 1 0 0 1 1 1 1 WW domain Nup35_RRM PF05172.13 EAN34439.1 - 1.3e-08 34.7 0.6 0.00025 21.0 0.1 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EAN34439.1 - 5.4e-07 29.7 0.1 0.00065 19.8 0.0 2.8 2 2 0 2 2 2 2 RNA recognition motif RNA_bind PF08675.11 EAN34439.1 - 4.9e-05 23.3 0.3 0.0032 17.5 0.2 2.9 2 1 0 2 2 2 1 RNA binding domain DUF1866 PF08952.11 EAN34439.1 - 0.0015 18.4 0.0 0.73 9.7 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.6 EAN34439.1 - 0.0028 17.6 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EAN34439.1 - 0.011 16.0 0.2 0.24 11.6 0.1 2.7 2 2 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter BRAP2 PF07576.12 EAN34439.1 - 0.019 15.2 0.0 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 BRCA1-associated protein 2 RRM_5 PF13893.6 EAN34439.1 - 0.022 14.4 0.1 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EAN34439.1 - 0.074 13.0 0.0 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 RL domain RRM_occluded PF16842.5 EAN34439.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 EAN34439.1 - 0.17 11.9 0.0 0.86 9.7 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif MA3 PF02847.17 EAN34440.1 - 7.2e-21 74.3 4.8 7.2e-21 74.3 4.8 2.3 2 0 0 2 2 2 1 MA3 domain Herpes_U30 PF04523.13 EAN34440.1 - 0.00085 17.3 0.2 0.0012 16.9 0.2 1.2 1 0 0 1 1 1 1 Herpes virus tegument protein U30 Cnd1 PF12717.7 EAN34440.1 - 0.011 15.8 0.1 0.037 14.1 0.1 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 CSG2 PF16965.5 EAN34440.1 - 0.079 11.9 0.6 0.42 9.5 0.0 2.1 1 1 0 2 2 2 0 Ceramide synthase regulator Ribosomal_S8 PF00410.19 EAN34441.1 - 1.2e-16 60.8 0.0 1.4e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ras PF00071.22 EAN34442.1 - 7.7e-57 191.4 0.3 9.7e-57 191.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAN34442.1 - 8.3e-35 119.6 0.7 1.2e-34 119.1 0.2 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAN34442.1 - 5.8e-13 48.7 0.1 1.1e-12 47.8 0.1 1.4 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAN34442.1 - 4.8e-08 33.1 0.4 7.4e-08 32.5 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAN34442.1 - 0.00028 20.5 0.0 0.026 14.1 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAN34442.1 - 0.0025 17.8 0.2 0.72 9.7 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EAN34442.1 - 0.0039 16.6 0.1 0.012 15.0 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAN34442.1 - 0.02 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EAN34442.1 - 0.021 14.3 0.1 0.055 13.0 0.1 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 EAN34442.1 - 0.07 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Peptidase_C97 PF05903.14 EAN34443.1 - 2.4e-20 72.9 0.9 4e-20 72.2 0.9 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Peptidase_C97 PF05903.14 EAN34444.1 - 9.4e-06 25.5 0.1 1.3e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 PPPDE putative peptidase domain RRM_1 PF00076.22 EAN34445.1 - 8.1e-29 99.3 0.1 1.5e-13 50.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAN34445.1 - 5.3e-05 22.8 0.0 0.43 10.2 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAN34445.1 - 0.00031 20.8 0.0 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EAN34445.1 - 0.074 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif LuxT_C PF18285.1 EAN34446.1 - 0.054 14.0 0.2 0.86 10.2 0.0 2.2 2 0 0 2 2 2 0 Tetracycline repressor LuxT C-terminal domain DpnII PF04556.12 EAN34447.1 - 0.11 11.8 1.9 0.26 10.6 0.4 1.9 1 1 1 2 2 2 0 DpnII restriction endonuclease Mito_carr PF00153.27 EAN34448.1 - 2.2e-08 33.9 0.3 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein PTSIIB_sorb PF03830.15 EAN34448.1 - 0.063 13.5 0.1 0.096 12.9 0.1 1.2 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component Peptidase_M29 PF02073.15 EAN34449.1 - 0.067 12.0 0.1 0.77 8.5 0.1 2.0 2 0 0 2 2 2 0 Thermophilic metalloprotease (M29) SRP_SPB PF02978.19 EAN34449.1 - 0.079 13.6 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Signal peptide binding domain tRNA-synt_1g PF09334.11 EAN34450.1 - 6.7e-74 249.0 0.4 1.1e-40 139.6 0.1 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EAN34450.1 - 1.3e-11 43.5 1.3 9.6e-06 24.1 0.1 3.5 2 2 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EAN34450.1 - 1.4e-09 37.8 0.0 1.9e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EAN34450.1 - 6.4e-07 29.4 0.1 1.4e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DALR_1 PF05746.15 EAN34450.1 - 0.17 12.1 0.8 1.4 9.1 0.1 2.4 2 1 1 3 3 3 0 DALR anticodon binding domain DUF1796 PF08795.10 EAN34450.1 - 0.21 11.5 1.7 4.9 7.1 0.4 2.4 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) UTP25 PF06862.12 EAN34451.1 - 2e-138 462.1 11.3 2.5e-138 461.8 11.3 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 zf-RING_2 PF13639.6 EAN34452.1 - 2.2e-12 47.1 7.5 2.2e-12 47.1 7.5 1.9 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAN34452.1 - 8e-09 35.2 5.5 2.2e-08 33.8 5.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAN34452.1 - 6.3e-08 32.2 2.8 6.3e-08 32.2 2.8 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EAN34452.1 - 1.1e-07 32.1 9.0 1.1e-07 32.1 9.0 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAN34452.1 - 1.7e-05 24.6 5.5 1.7e-05 24.6 5.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAN34452.1 - 2.8e-05 24.0 1.9 2.8e-05 24.0 1.9 2.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EAN34452.1 - 9.3e-05 22.4 4.1 0.00023 21.1 4.1 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EAN34452.1 - 0.00014 21.7 4.8 0.00014 21.7 4.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EAN34452.1 - 0.0031 17.3 3.3 0.0031 17.3 3.3 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EAN34452.1 - 0.0057 16.8 5.7 0.0057 16.8 5.7 2.4 2 1 0 2 2 2 1 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 EAN34452.1 - 0.032 14.4 2.1 0.032 14.4 2.1 1.9 2 0 0 2 2 2 0 PHD-zinc-finger like domain DZR PF12773.7 EAN34452.1 - 0.086 12.9 6.7 0.43 10.6 0.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-Nse PF11789.8 EAN34452.1 - 0.1 12.4 2.2 0.21 11.4 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_9 PF14369.6 EAN34452.1 - 2.2 8.6 10.1 2.4 8.5 4.3 3.3 3 1 0 3 3 3 0 zinc-ribbon zf-CHY PF05495.12 EAN34452.1 - 2.7 8.5 9.6 0.36 11.3 0.4 2.7 2 1 1 3 3 3 0 CHY zinc finger zf-HC5HC2H PF13771.6 EAN34452.1 - 3.3 8.0 9.5 0.083 13.2 1.4 2.3 2 1 0 2 2 2 0 PHD-like zinc-binding domain Prok-RING_4 PF14447.6 EAN34452.1 - 7.9 6.4 11.9 2.4 8.1 6.6 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 MCM6_C PF18263.1 EAN34453.1 - 1.8e-05 24.9 0.0 2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain Cyclin_N PF00134.23 EAN34454.1 - 1.3e-07 31.4 2.7 1.5e-07 31.2 0.3 2.1 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAN34454.1 - 0.0032 17.6 0.7 0.0086 16.2 0.2 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 EAN34454.1 - 0.034 14.5 0.0 0.063 13.7 0.0 1.7 1 1 0 1 1 1 0 Cyclin C-terminal domain TFIIB PF00382.19 EAN34454.1 - 0.13 12.3 0.8 0.86 9.7 0.1 2.2 2 0 0 2 2 2 0 Transcription factor TFIIB repeat FAINT PF04385.15 EAN34455.1 - 1.6e-05 24.9 0.1 4.2e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function, DUF529 FAINT PF04385.15 EAN34456.1 - 1.1e-07 31.8 0.9 1.7e-07 31.2 0.4 1.6 1 1 0 1 1 1 1 Domain of unknown function, DUF529 PS_Dcarbxylase PF02666.15 EAN34457.1 - 2.3e-31 108.9 0.9 1.7e-30 106.1 0.9 1.9 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 EAN34457.1 - 0.0003 20.5 0.2 1.3 8.9 0.0 3.5 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 EAN34457.1 - 0.0017 18.1 0.2 16 5.4 0.0 3.3 3 0 0 3 3 3 1 Biotin-requiring enzyme HlyD_3 PF13437.6 EAN34457.1 - 0.036 14.8 0.0 8.2 7.2 0.0 3.1 3 0 0 3 3 3 0 HlyD family secretion protein RnfC_N PF13375.6 EAN34457.1 - 0.041 13.8 1.9 7 6.7 0.0 3.3 1 1 3 4 4 4 0 RnfC Barrel sandwich hybrid domain DUF4131 PF13567.6 EAN34457.1 - 0.043 13.5 0.0 0.091 12.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_M23 PF01551.22 EAN34457.1 - 0.064 13.5 0.2 5 7.4 0.0 2.8 1 1 2 3 3 3 0 Peptidase family M23 FAINT PF04385.15 EAN34459.1 - 1.2e-81 268.8 121.9 3.6e-08 33.3 3.8 15.7 15 1 0 15 15 15 15 Domain of unknown function, DUF529 FAINT PF04385.15 EAN34460.1 - 2.8e-34 117.0 45.5 5.6e-07 29.5 0.3 8.0 7 1 1 8 8 8 6 Domain of unknown function, DUF529 FAINT PF04385.15 EAN34461.1 - 7.5e-60 199.0 77.9 2.1e-07 30.9 1.8 11.3 11 0 0 11 11 11 11 Domain of unknown function, DUF529 ANAPC4_WD40 PF12894.7 EAN34461.1 - 0.005 17.1 0.5 0.3 11.4 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SPX PF03105.19 EAN34461.1 - 1.8 8.4 16.1 22 4.8 0.0 2.2 2 0 0 2 2 2 0 SPX domain FAINT PF04385.15 EAN34462.1 - 4.1e-10 39.6 6.6 1.2e-05 25.3 0.1 3.9 3 1 0 3 3 3 3 Domain of unknown function, DUF529 FAINT PF04385.15 EAN34463.1 - 0.066 13.3 10.6 1.5 8.9 0.7 3.0 2 0 0 2 2 2 0 Domain of unknown function, DUF529 FAINT PF04385.15 EAN34464.1 - 7.5e-06 25.9 16.4 7.2e-05 22.8 2.8 2.8 3 0 0 3 3 3 2 Domain of unknown function, DUF529 Tash_PEST PF07708.11 EAN34465.1 - 0.0025 17.9 4.5 0.0081 16.3 4.5 2.0 1 0 0 1 1 1 1 Tash protein PEST motif # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Theileria_parva-ASM16536v1/GCA_000165365.1_ASM16536v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Theileria_parva-ASM16536v1/GCA_000165365.1_ASM16536v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Theileria_parva-ASM16536v1/GCA_000165365.1_ASM16536v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Theileria_parva-ASM16536v1/GCA_000165365.1_ASM16536v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 01:28:02 2019 # [ok]